Systemic inflammatory diseases and silicone breast prostheses: report of a case of adult still disease and review of the literature.
There has been a debate about the possibility of a link between silicone breast implants and the onset of systemic connective tissue diseases (eg, scleroderma, systemic lupus erythematosus, rheumatoid arthritis) and other inflammatory pathologies, such as silicone implant associated syndrome and adult Still disease. We report a case of adult Still disease in a patient with a silicone gel breast implant. The disease regressed with steroidal treatment, and the patient is now no longer steroid-dependent, although the implant is still in place.
Montalto
Massimo
M
Institute of Internal Medicine, Catholic University, Rome, Italy. mmontalto@rm.unicatt.it
Vastola
Monica
M
Santoro
Luca
L
La Regina
Micaela
M
Curigliano
Valentina
V
Manna
Raffaele
R
Gasbarrini
Giovanni
G
D000328:Adult; D018427:Breast Implants / Q000009:adverse effects*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use; D020034:Silicone Gels / Q000009:adverse effects*; D016706:Still's Disease, Adult-Onset / Q000188:drug therapy / Q000209:etiology*
D005938:Glucocorticoids; D020034:Silicone Gels; D008775:Methylprednisolone