Central pontine myelinolysis induced by hypophosphatemia following Wernicke's encephalopathy.
A 62-year-old woman, after a resection and ileostomy for multiple perforations of the terminal ileum and prolonged postoperative parenteral nutrition, developed thiamine deficiency with clinical and magnetic resonance imaging features of Wernicke's disease. Later on the patient developed central pontine myelinolysis. For this condition, a pathogenetic role of a transient hypophosphatemia was suggested by both laboratory data and course of the disease.
Falcone
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Belcolle Hospital, Viterbo, Italy.
Compagnoni
A
A
Meschini
C
C
Perrone
C
C
Nappo
A
A
D004573:Electrolytes / Q000097:blood; D005260:Female; D006801:Humans; D017674:Hypophosphatemia / Q000150:complications* / Q000601:surgery; D007081:Ileostomy / Q000379:methods; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D017590:Myelinolysis, Central Pontine / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D013832:Thiamine Deficiency; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014899:Wernicke Encephalopathy / Q000209:etiology* / Q000473:pathology / Q000601:surgery
D004573:Electrolytes