[Study on supercritical CO2 extraction of lecithin from radix Polygoni Multiflori Preparata by orthogonal design].
OBJECTIVE
To find out the optimal supercritical CO2 fluid extraction process for Radix Polygoni Multiflori Preparata, the extraction process was studied by orthogonal design with the yield of lectithin as index.


METHODS
Four factors were chosen in this experiment, including extractor pressure, extractor temperature, separator I pressure and separator I temperature. The ultraviolet visible spectrophotometry was applied for the determination of lecithin in all different experimental conditions.


RESULTS
The optimal supercritical CO2 fluid extraction process was: extractor pressure 32 MPa, extractor temperature 50 degrees C, separator I pressure 6 MPa and separator I temperature 55 degrees C.


CONCLUSIONS
Compared with the traditional extraction methods, SFE-CO2 process has the predominance of saving solvent and shortening the technology process, which is exactly suitable for industralization manufacture.
Bai
Yan
Y
Guangdong College of Pharmacy, Guangzhou 510224.
Ge
Fahuan
F
D000704:Analysis of Variance; D002245:Carbon Dioxide; D025924:Chromatography, Supercritical Fluid; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification*; D010713:Phosphatidylcholines / Q000032:analysis / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D019664:Polygonaceae / Q000737:chemistry*; D011312:Pressure; D013678:Technology, Pharmaceutical / Q000379:methods; D013696:Temperature
D004365:Drugs, Chinese Herbal; D010713:Phosphatidylcholines; D002245:Carbon Dioxide