title: [Study on supercritical CO2 extraction of lecithin from radix Polygoni Multiflori Preparata by orthogonal design].
abstract: OBJECTIVE
  To find out the optimal supercritical CO2 fluid extraction process for Radix Polygoni Multiflori Preparata, the extraction process was studied by orthogonal design with the yield of lectithin as index.
  
  
  METHODS
  Four factors were chosen in this experiment, including extractor pressure, extractor temperature, separator I pressure and separator I temperature. The ultraviolet visible spectrophotometry was applied for the determination of lecithin in all different experimental conditions.
  
  
  RESULTS
  The optimal supercritical CO2 fluid extraction process was: extractor pressure 32 MPa, extractor temperature 50 degrees C, separator I pressure 6 MPa and separator I temperature 55 degrees C.
  
  
  CONCLUSIONS
  Compared with the traditional extraction methods, SFE-CO2 process has the predominance of saving solvent and shortening the technology process, which is exactly suitable for industralization manufacture.
authors.affiliation: Guangdong College of Pharmacy, Guangzhou 510224.
authors.forename: Yan
authors.initials: Y
authors.lastname: Bai
authors.forename: Fahuan
authors.initials: F
authors.lastname: Ge
mesh_terms: D000704:Analysis of Variance; D002245:Carbon Dioxide; D025924:Chromatography, Supercritical Fluid; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification*; D010713:Phosphatidylcholines / Q000032:analysis / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D019664:Polygonaceae / Q000737:chemistry*; D011312:Pressure; D013678:Technology, Pharmaceutical / Q000379:methods; D013696:Temperature
chemical_list: D004365:Drugs, Chinese Herbal; D010713:Phosphatidylcholines; D002245:Carbon Dioxide