title: Systemic inflammatory diseases and silicone breast prostheses: report of a case of adult still disease and review of the literature.
abstract: There has been a debate about the possibility of a link between silicone breast implants and the onset of systemic connective tissue diseases (eg, scleroderma, systemic lupus erythematosus, rheumatoid arthritis) and other inflammatory pathologies, such as silicone implant associated syndrome and adult Still disease. We report a case of adult Still disease in a patient with a silicone gel breast implant. The disease regressed with steroidal treatment, and the patient is now no longer steroid-dependent, although the implant is still in place.
authors.affiliation: Institute of Internal Medicine, Catholic University, Rome, Italy. mmontalto@rm.unicatt.it
authors.forename: Massimo
authors.initials: M
authors.lastname: Montalto
authors.forename: Monica
authors.initials: M
authors.lastname: Vastola
authors.forename: Luca
authors.initials: L
authors.lastname: Santoro
authors.forename: Micaela
authors.initials: M
authors.lastname: La Regina
authors.forename: Valentina
authors.initials: V
authors.lastname: Curigliano
authors.forename: Raffaele
authors.initials: R
authors.lastname: Manna
authors.forename: Giovanni
authors.initials: G
authors.lastname: Gasbarrini
mesh_terms: D000328:Adult; D018427:Breast Implants / Q000009:adverse effects*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use; D020034:Silicone Gels / Q000009:adverse effects*; D016706:Still's Disease, Adult-Onset / Q000188:drug therapy / Q000209:etiology*
chemical_list: D005938:Glucocorticoids; D020034:Silicone Gels; D008775:Methylprednisolone