title: Body mass index. An additional prognostic factor in ICU patients.
abstract: OBJECTIVE
  To examine the association between body mass index (BMI) and mortality in adult intensive care unit (ICU) patients. DESIGN. A prospective multi-center study.
  
  
  METHODS
  None.
  
  
  METHODS
  A cohort study (yielding the OUTCOMEREA database) was conducted over 2 years in 6 medical-surgical ICUs. In each participating ICU, the following were collected daily: demographic information, admission height and weight, comorbidities, severity scores (SAPS II, LOD, and SOFA), ICU and hospital lengths of stay, and ICU and hospital mortality rates.
  
  
  RESULTS
  A total of 1,698 patients were examined and divided into 4 groups based on BMI: <18.5, 18.5-24.9, 25-29.9, and >30 kg/m(2). These groups differed significantly for age, gender, admission category (medical, scheduled surgery, unscheduled surgery), ICU and hospital lengths of stay, and comorbidities. Severity at admission and within the first 2 days was similar in the 4 groups, except for the SOFA score. Overall hospital mortality was 31.3% (532 out of 1,698 patients). By multivariate analysis, a BMI below 18.5 kg/m(2) was independently associated with increased mortality (odds ratio 1.63; 95% confidence intervals 1.11-2.39). None of the other BMI categories were associated with higher mortality and even a BMI>30 kg/m(2) was protective of mortality (odds ratio 0.60, 95% confidence intervals 0.40-0.88).
  
  
  CONCLUSIONS
  A low BMI was independently associated with higher mortality and a high BMI with lower mortality in this large cohort of critically ill patients. Since BMI is absent from currently available scoring systems, further studies are needed to determine whether adding BMI would improve the effectiveness of scores in predicting mortality.
authors.affiliation: Service de Réanimation Polyvalente, Hôpital Saint Joseph, 185 rue Raymond Losserand, 75014 Paris, France. mgarrouste@hopital-saint-joseph.org
authors.forename: Maité
authors.initials: M
authors.lastname: Garrouste-Orgeas
authors.forename: Gilles
authors.initials: G
authors.lastname: Troché
authors.forename: Elie
authors.initials: E
authors.lastname: Azoulay
authors.forename: Antoine
authors.initials: A
authors.lastname: Caubel
authors.forename: Arnaud
authors.initials: A
authors.lastname: de Lassence
authors.forename: Christine
authors.initials: C
authors.lastname: Cheval
authors.forename: Laurent
authors.initials: L
authors.lastname: Montesino
authors.forename: Marie
authors.initials: M
authors.lastname: Thuong
authors.forename: François
authors.initials: F
authors.lastname: Vincent
authors.forename: Yves
authors.initials: Y
authors.lastname: Cohen
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Timsit
mesh_terms: D000368:Aged; D015992:Body Mass Index; D005260:Female; D005602:France / Q000453:epidemiology; D006305:Health Status Indicators; D017052:Hospital Mortality; D006801:Humans; D007362:Intensive Care Units; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011446:Prospective Studies; D012306:Risk