title: Efficient resolution of 2,2'-dihydroxy-1,1'-binaphthyl by inclusion complexation with chiral N-(3-chloro-2-hydroxypropyl)-N,N,N-trimethylammonium chloride.
abstract: The complete resolution of 2,2[prime or minute]-dihydroxy-1,1[prime or minute]-binaphthyl into its enantiomers by inclusion complexation with a commercially available derivative of choline, is reported. The two enantiomers are recovered in >99% ee from the inclusion complexes by simple dissolution in a diethyl ether-water medium and the resolving agent can be recycled.
authors.affiliation: Department of Chemistry, Faculty of Science, Okayama University of Science, Okayama 700-0005, Japan. toda@chem.ous.ac.jp
authors.forename: Fumio
authors.initials: F
authors.lastname: Toda
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yoshizawa
authors.forename: Shunji
authors.initials: S
authors.lastname: Hyoda
authors.forename: Shinji
authors.initials: S
authors.lastname: Toyota
authors.forename: Spyros
authors.initials: S
authors.lastname: Chatziefthimiou
authors.forename: Irene M
authors.initials: IM
authors.lastname: Mavridis