[Anti-lipid peroxidaton of the water extract from cornu cervi pantotrichum].
OBJECTIVE
To investigate the anti-lipid peroxidation of the water extract from Cornu Cervi Pantotrichum (WECCP) in vitro.


METHODS
The lipid peroxidation (malondialdehyde formation) in microsomes of rat brain, liver and kidney induced by NADPH-Vit C and cyctein-Fe2+, and the superoxide anion radical production (reduced cytochrome c formation) in xanthine-xanthine oxidase system in vitro were evaluated.


RESULTS
The lipid peroxidation (MDA formation) in microsomes of rat brain, liver and kidney induced by NADPH-Vit C and cyctein-Fe2+, O2 production(reduced cytochrome c formation) in xanthine-xanthine oxidase system were significantly inhibited by WECCP.


CONCLUSIONS
WECCP exhibits an antioxidant activity.
Chen
Xiaoguang
X
Academy of Traditional Chinese Medicine and Materia Medica of Jilin Province, Changchun 130021.
Jin
Shuli
S
Di
Lin
L
Liu
Xinyu
X
Song
Haipeng
H
D000818:Animals; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology*; D001921:Brain / Q000378:metabolism; D003670:Deer; D066298:In Vitro Techniques; D007668:Kidney / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D008419:Materia Medica / Q000302:isolation & purification / Q000494:pharmacology*; D051379:Mice; D008861:Microsomes / Q000187:drug effects / Q000378:metabolism; D008862:Microsomes, Liver / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D014969:Xanthine Oxidase / Q000378:metabolism
D000975:Antioxidants; D008419:Materia Medica; D008315:Malondialdehyde; D014969:Xanthine Oxidase