title: A case of sectorial benign flecked retina.
abstract: OBJECTIVE
  A case of sectorial benign flecked retina not associated with an RDH5 gene mutation is reported.
  
  
  METHODS
  A 51-year-old woman showed multiple yellow-white flecks in both eyes similar to those of benign flecked retina but in only the upper half of the retina. We carried out clinical, electrophysiological, and molecular genetic examinations of the patient.
  
  
  RESULTS
  Visual acuity was 20/20 OD and 20/20 OS. Fluorescein angiography showed diffuse irregular hypofluorescence that did not correspond to the flecked lesions. A Goldmann-Weeker adaptometer test revealed that the visual threshold of the upper retina was approximately 0.6 to 0.8 log units higher than that of the lower retina. No mutations of the RDH5 gene were detected in exons 2-5 or in the flanking intron sequences.
  
  
  CONCLUSIONS
  To our knowledge, this is the first report of sectorial benign flecked retina, and the flecks may not be caused by an RDH5 gene mutation.
authors.affiliation: Department of Ophthalmology, Hamamatsu University School of Medicine, Hamamatsu, Japan.
authors.forename: Takako
authors.initials: T
authors.lastname: Tsuchiya
authors.forename: Masaru
authors.initials: M
authors.lastname: Kato
authors.forename: Natsuyo
authors.initials: N
authors.lastname: Tomita
authors.forename: Kenro
authors.initials: K
authors.lastname: Koide
authors.forename: Norimasa
authors.initials: N
authors.lastname: Hata
authors.forename: Miho
authors.initials: M
authors.lastname: Sato
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Hotta
authors.forename: Makoto
authors.initials: M
authors.lastname: Ueno
authors.forename: Makoto
authors.initials: M
authors.lastname: Nakamura
authors.forename: Yozo
authors.initials: Y
authors.lastname: Miyake
mesh_terms: D000429:Alcohol Oxidoreductases / Q000235:genetics; D003623:Dark Adaptation; D004596:Electroretinography; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008875:Middle Aged; D012164:Retinal Diseases / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D014792:Visual Acuity
chemical_list: D000429:Alcohol Oxidoreductases; C022520:retinol dehydrogenase