title: [A case of primary squamous cell carcinoma of the lung with a metastatic thyroid tumor improved following chemotherapy].
abstract: Metastatic thyroid tumor is rarely diagnosed clinically. We report here a case of a 59-year-old male of a primary squamous cell carcinoma of the lung with metastatic thyroid tumor diagnosed by an ultrasonography-guided aspiration cytology. A squamous cell carcinoma of the lung (c-T4N3M1 stage IV) was diagnosed in March 2001, and so chemotherapy using carboplatin and paclitaxel was tried initially. A partial response was obtained. Then, he was re-admitted to our hospital because his thyroid gland was swollen. Ultrasonography-guided aspiration cytology of the thyroid tumor was performed and revealed a metastatic squamous cell carcinoma from the lung cancer. The patient was given chemotherapy using gemcitabine and docetaxel as second line chemotherapy. This reduced the thyroid tumor size and improved the symptoms.
authors.affiliation: Department of Respiratory Medicine, Juntendo University School of Medicine, 2-1-1, Hongo, Bukyo-ku, Tokyo, 113-8421, Japan.
authors.forename: Michihiro
authors.initials: M
authors.lastname: Hirama
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Takahashi
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Takagi
authors.forename: Rina
authors.initials: R
authors.lastname: Ohhashi
authors.forename: Koji
authors.initials: K
authors.lastname: Suzuki
authors.forename: Koichi
authors.initials: K
authors.lastname: Sato
authors.forename: Kuniaki
authors.initials: K
authors.lastname: Seyama
authors.forename: Toshimasa
authors.initials: T
authors.lastname: Uekusa
authors.forename: Yoshinosuke
authors.initials: Y
authors.lastname: Fukuchi
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000556:secondary*; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D000077143:Docetaxel; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D043823:Taxoids / Q000008:administration & dosage; D013964:Thyroid Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D000093542:Gemcitabine
chemical_list: D000964:Antimetabolites, Antineoplastic; D000972:Antineoplastic Agents, Phytogenic; D043823:Taxoids; D003841:Deoxycytidine; D000077143:Docetaxel; D000093542:Gemcitabine