Novel estrogen receptor coregulators and signaling molecules in human diseases.
The steroid hormone estrogen and signaling from its receptors are increasingly recognized as critical mediators of a variety of organ-specific biological processes. Recent advances in the identification and functional characterization of novel estrogen receptor interacting proteins clearly show the complexity of hormonal signaling regulation, but may also contribute to our understanding of the roles of estrogen signaling in normal physiology and the pathobiology of human disease.
Barnes
C J
CJ
Department of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, Texas 77030, USA.
Vadlamudi
R K
RK
Kumar
R
R
D001842:Bone and Bones / Q000502:physiology; D002320:Cardiovascular Physiological Phenomena; D002843:Chromatin / Q000378:metabolism; D004967:Estrogens / Q000378:metabolism; D006801:Humans; D009369:Neoplasms / Q000378:metabolism; D018696:Neuroprotective Agents / Q000378:metabolism; D009687:Nuclear Proteins / Q000378:metabolism; D011960:Receptors, Estrogen / Q000378:metabolism*; D012097:Repressor Proteins / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology*
D002843:Chromatin; D004967:Estrogens; D018696:Neuroprotective Agents; D009687:Nuclear Proteins; D011960:Receptors, Estrogen; D012097:Repressor Proteins