[Influence of Scutellaria barbata on calcium beaconage of cervix cancer cells].
To study the influence of Scutellaria barbata D. Don on cytoplasmatic free Ca2+ concentration of cervix cancer cells and its mechanism on anti-cancer. Fluorochrome Fura-2 could combine with free Ca2+ and then give off fluorescent under the condition of stimulating by some wavelength light. The changes of free Ca2+ were tested according to the intensity of fluorescent. The results showed that Scutellaria barbata D. Don could stimulate the cytoplasmatic store-calcium out-flow and extracellular Ca2+ inflow, and could obviously improve the concentration of cytoplasmatic free Ca2+.
Gao
Dong
D
Fujian College of Traditional Chinese Medicine, Fuzhou 350003.
Gao
Yonglin
Y
Bai
Ping
P
D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism*; D015220:Calcium Channels / Q000187:drug effects; D020013:Calcium Signaling / Q000187:drug effects* / Q000502:physiology; D002455:Cell Division / Q000187:drug effects; D003600:Cytosol / Q000378:metabolism; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D016257:Fura-2; D006367:HeLa Cells; D006801:Humans; D031363:Scutellaria / Q000737:chemistry; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D015220:Calcium Channels; D004365:Drugs, Chinese Herbal; D002118:Calcium; D016257:Fura-2