Use of potentiated antibiotics in wound management.
Prevention or resolution of microbial colonization of wounds is critical to rapid and uneventful healing. The use and misuse of antimicrobial agents continues to support the evolution of multidrug resistant organisms that can cause severe or life-threatening infections. Chelating agents have been shown to potentiate the effects of antimicrobial compounds. The third generation chelating agent. Tricide has been shown to be effective against many multidrug resistant pathogens, prevents pathogens from development resistance to the antimicrobials with which it is mixed and substantially reduces the amount of antimicrobials needed to kill bacteria and fungi.
Ritchie
Branson W
BW
Departments of Small Animal Medicine and Medical Microbiology and Parasitology, University of Georgia, College of Veterinary Medicine, Athens, GA 30602, USA. britchie@vet.uga.edu
Wooley
Richard E
RE
Kemp
Douglas T
DT
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D004357:Drug Synergism; D017192:Skin Diseases, Bacterial / Q000517:prevention & control / Q000662:veterinary*; D014945:Wound Healing; D014947:Wounds and Injuries / Q000628:therapy / Q000662:veterinary*
D000900:Anti-Bacterial Agents