Therapeutic efficacy of laparoscopic cholecystectomy in the treatment of biliary dyskinesia.
BACKGROUND
The outcome of laparoscopic cholecystectomy for patients who present with "classic" biliary colic without evidence of cholelithiasis or acute inflammation (biliary dyskinesia) is not well documented. This study evaluates whether a cholecystokinin dimethyl iminodiacetic acid (CCK-HIDA) scan can predict relief of symptoms in this group of patients.


METHODS
Patients who underwent laparoscopic cholecystectomy after a normal ultrasound and with an abnormal dimethyl iminodiacetic acid scan were retrospectively reviewed. Symptomatic improvement was correlated with degree of dyskinesia, histologic findings, sex, and age.


RESULTS
One hundred seventy-six patients were studied and 69% were available for followup at a mean interval of 16 months. One hundred fourteen patients (94%) had complete or partial relief of symptoms. No correlation was found between degree of relief and degree of impaired ejection (31% to 50% versus <30%), the histologic findings, sex, or age.


CONCLUSIONS
Abnormal cholecystokinin dimethyl iminodiacetic acid scan effectively predicts relief of symptoms in patients undergoing laparoscopic cholecystectomy for biliary dyskinesia.
Patel
Nilesh A
NA
Department of Surgery, Allegheny General Hospital, Pittsburgh, PA, USA.
Lamb
Jason J
JJ
Hogle
Nancy J
NJ
Fowler
Dennis L
DL
D001657:Biliary Dyskinesia / Q000000981:diagnostic imaging* / Q000601:surgery*; D017081:Cholecystectomy, Laparoscopic; D002766:Cholecystokinin; D005260:Female; D005765:Gastrointestinal Agents; D006801:Humans; D007098:Imino Acids; D008297:Male; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D016896:Treatment Outcome
D005765:Gastrointestinal Agents; D007098:Imino Acids; D019275:Radiopharmaceuticals; D002766:Cholecystokinin; C008109:iminodiacetic acid