Comparison of LCx with other current viral load assays for detecting and quantifying human immunodeficiency virus type 1 RNA in patients infected with the circulating recombinant form A/G (CRF02).
LCx was compared to other assays in measuring human immunodeficiency virus type 1 (HIV-1) CRF02 viremia. LCx showed significant but low correlation with the other methods. Values of <2.60 log(10) cp/ml were observed in 29.6% of specimens with LCx and in only 14.8% with bDNA and PCR, suggesting suboptimal performance of LCx with CRF02.
Amendola
Alessandra
A
National Institute for Infectious Diseases "Lazzaro Spallanzani," Rome, Italy.
Bordi
Licia
L
Angeletti
Claudio
C
Girardi
Enrico
E
Ippolito
Giuseppe
G
Capobianchi
Maria R
MR
D000163:Acquired Immunodeficiency Syndrome / Q000097:blood* / Q000175:diagnosis; D015497:HIV-1 / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D012367:RNA, Viral / Q000097:blood* / Q000302:isolation & purification; D019562:Viral Load; D014766:Viremia / Q000097:blood / Q000175:diagnosis; D014773:Virology / Q000379:methods
D012367:RNA, Viral