title: Microwave-assisted synthesis of allylic amines: considerable rate acceleration in the hydrozirconation-transmetalation-aldimine addition sequence.
abstract: The hydrozirconation of alkynes with zirconocene hydrochloride and the dimethylzinc-mediated addition of alkenylzirconocenes to diphenylphosphinoyl imines can be greatly accelerated with microwave irradiation, resulting in a convenient and rapid one-pot process for the preparation of synthetically useful allylic amines.
authors.affiliation: Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA. pwipf@pitt.edu
authors.forename: Peter
authors.initials: P
authors.lastname: Wipf
authors.forename: Jelena
authors.initials: J
authors.lastname: Janjic
authors.forename: Corey R J
authors.initials: CR
authors.lastname: Stephenson
mesh_terms: D000498:Allyl Compounds / Q000138:chemical synthesis*; D000588:Amines / Q000138:chemical synthesis*; D006859:Hydrogen / Q000737:chemistry*; D007097:Imines / Q000737:chemistry*; D008872:Microwaves; D015394:Molecular Structure; D017640:Silicates / Q000737:chemistry*; D015040:Zirconium / Q000737:chemistry*
chemical_list: D000498:Allyl Compounds; D000588:Amines; D007097:Imines; D017640:Silicates; C003784:zircon; D006859:Hydrogen; D015040:Zirconium