title: Foetal intralobar lung sequestration: antenatal diagnosis and management.
abstract: OBJECTIVE
  The objectives of this study are to discuss the use of ultrasonography for the diagnosis of foetal intralobar sequestration (FILS) antenatally and the management options available for these pregnancies.
  
  
  METHODS
  This is a retrospective review of six cases of FILS diagnosed antenatally by two dimensional (2D) and colour Doppler ultrasonography out of a total of 31,508 deliveries over a two-year period at the KK Women's and Children's Hospital.
  
  
  RESULTS
  The incidence of FILS in this hospital was 1 in 5,251 deliveries. 2D ultrasonography showed an echogenic lung in all cases. FILS was confirmed by the demonstration of a systemic vessel leading to the affected lung on colour Doppler examination. After counselling, four terminated their pregnancies during mid-trimester, while two continued their pregnancies to term. Confirmation of the terminated cases was by post-mortem. In the two pregnancies that continued, regular growth scans were done to monitor the progression of the condition. Computed tomography confirmed the diagnosis post-delivery. Both were well but one had a resection of the sequestrated lung although he was asymptomatic. Histology also confirmed the diagnosis.
  
  
  CONCLUSIONS
  FILS is a rare anomaly. 2D and colour Doppler ultrasonography are used to diagnose the condition antenatally. Termination of the pregnancy is not always indicated, as there are favourable outcomes from FILS.
authors.affiliation: Department of Maternal-Foetal Medicine, KK Women's and Children's Hospital (KKWCH), 100 Bukit Timah Road, Singapore 229899. jeanchensc@yahoo.co.uk
authors.forename: J S C
authors.initials: JS
authors.lastname: Chen
authors.forename: N
authors.initials: N
authors.lastname: Walford
authors.forename: Y L
authors.initials: YL
authors.lastname: Yan
authors.forename: C L
authors.initials: CL
authors.lastname: Ong
authors.forename: G S H
authors.initials: GS
authors.lastname: Yeo
mesh_terms: D000328:Adult; D001998:Bronchopulmonary Sequestration / Q000000981:diagnostic imaging* / Q000628:therapy*; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000628:therapy*; D006801:Humans; D008297:Male; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012189:Retrospective Studies; D014463:Ultrasonography