Pharmacobezoar complicating treatment with sodium alginate.
We encountered a gastric bezoar that had developed in a 9-year-old girl treated with sodium alginate (Alloid G) for acute gastritis associated with systemic lupus erythematosus. A hard mass palpated in the left upper abdomen proved, upon gastric endoscopy, to be an intragastric foreign body. Sodium alginate was detected in an analysis of a sample from this bezoar. In an in vitro simulation, sodium alginate solidified when mixed with the patient's other medicines. The bezoar caused no complications, and disappeared spontaneously after discontinuation of the medications. This case indicates that this sodium alginate preparation, Alloid G, can be a cause of pharmacobezoar.
Kaneko
Hiroaki
H
Department of Pediatrics, Gunma University School of Medicine, 3-39-15 Showa-machi, Maebashi 371-8511, Japan.
Tomomasa
Takeshi
T
Kubota
Yumi
Y
Todokoro
Makoto
M
Kato
Masahiko
M
Miyazawa
Reiko
R
Suzuki
Tomoko
T
Hatori
Yukie
Y
Kunimoto
Fumio
F
Yamamoto
Koujirou
K
Morikawa
Akihiro
A
D000464:Alginates / Q000009:adverse effects* / Q000627:therapeutic use; D001630:Bezoars; D002648:Child; D005260:Female; D005756:Gastritis / Q000188:drug therapy; D020723:Glucuronic Acid / Q000009:adverse effects* / Q000627:therapeutic use; D006490:Hemostatics / Q000009:adverse effects* / Q000627:therapeutic use; D006603:Hexuronic Acids / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D013270:Stomach
D000464:Alginates; D006490:Hemostatics; D006603:Hexuronic Acids; D020723:Glucuronic Acid