N-(2-Fluoroethyl)-3beta-(4-iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2alpha-carboxamide: a new cocaine derivative with equatorially attached ligands.
In the title compound, C(17)H(22)FIN(2)O, both the amide and the iodophenyl substituents of the tropane ring lie in equatorial positions. The crystal packing is determined by N-H.O and C-H.F intermolecular hydrogen-bonding interactions.
Krebs
Birte
B
Institut für Nuklearchemie (INC), Forschungszentrum Jülich, D-52425 Jülich, Germany.
Flörke
Ulrich
U
D003042:Cocaine / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000378:metabolism; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D008024:Ligands; D011849:Radioactive Tracers
D008024:Ligands; C487159:N-(2-fluoroethyl)-3beta-(4-iodophenyl)-8-methyl-8-azabicyclo(3.2.1)octane-2alpha-carboxamide; D011849:Radioactive Tracers; D003042:Cocaine