title: Therapeutic efficacy of laparoscopic cholecystectomy in the treatment of biliary dyskinesia.
abstract: BACKGROUND
  The outcome of laparoscopic cholecystectomy for patients who present with "classic" biliary colic without evidence of cholelithiasis or acute inflammation (biliary dyskinesia) is not well documented. This study evaluates whether a cholecystokinin dimethyl iminodiacetic acid (CCK-HIDA) scan can predict relief of symptoms in this group of patients.
  
  
  METHODS
  Patients who underwent laparoscopic cholecystectomy after a normal ultrasound and with an abnormal dimethyl iminodiacetic acid scan were retrospectively reviewed. Symptomatic improvement was correlated with degree of dyskinesia, histologic findings, sex, and age.
  
  
  RESULTS
  One hundred seventy-six patients were studied and 69% were available for followup at a mean interval of 16 months. One hundred fourteen patients (94%) had complete or partial relief of symptoms. No correlation was found between degree of relief and degree of impaired ejection (31% to 50% versus <30%), the histologic findings, sex, or age.
  
  
  CONCLUSIONS
  Abnormal cholecystokinin dimethyl iminodiacetic acid scan effectively predicts relief of symptoms in patients undergoing laparoscopic cholecystectomy for biliary dyskinesia.
authors.affiliation: Department of Surgery, Allegheny General Hospital, Pittsburgh, PA, USA.
authors.forename: Nilesh A
authors.initials: NA
authors.lastname: Patel
authors.forename: Jason J
authors.initials: JJ
authors.lastname: Lamb
authors.forename: Nancy J
authors.initials: NJ
authors.lastname: Hogle
authors.forename: Dennis L
authors.initials: DL
authors.lastname: Fowler
mesh_terms: D001657:Biliary Dyskinesia / Q000000981:diagnostic imaging* / Q000601:surgery*; D017081:Cholecystectomy, Laparoscopic; D002766:Cholecystokinin; D005260:Female; D005765:Gastrointestinal Agents; D006801:Humans; D007098:Imino Acids; D008297:Male; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D005765:Gastrointestinal Agents; D007098:Imino Acids; D019275:Radiopharmaceuticals; D002766:Cholecystokinin; C008109:iminodiacetic acid