title: Assessing past treatment history: test-retest reliability of the Treatment Response to Antidepressant Questionnaire.
abstract: A reliable and valid instrument has yet to be developed that elicits antidepressant treatment history via patient interview. The goal of the present study was to establish the test-retest reliability of the Treatment Response to Antidepressant Questionnaire (TRAQ). The TRAQ is a semistructured interview that was designed to collect systematically information regarding previous antidepressant treatment, adequacy of trials, and nature of response. Fifty subjects who sought outpatient treatment as part of the Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) project participated in the study. Patients were interviewed initially by a psychologist, who administered the TRAQ. An average of 5 to 6 days later, a psychiatrist who was blind to the results of the initial evaluation readministered the TRAQ to each of these patients. Reliability of recall of antidepressant trials, trial adequacy, and nature of response were evaluated using the kappa statistic. The mean duration of the TRAQ interviews was 3.30 minutes (SD=2.03 minutes). The reliability of recall of antidepressant trials ranged from 0.81 to 0.95, with an overall kappa of 0.91. The kappa for trial adequacy, depending on the definition used, ranged from 0.72 to 0.84. The kappa for determining positive versus negative response was 0.72. Thus, the test-retest reliability of the TRAQ was found to be in the good to excellent range for each of the principal outcome measures. The TRAQ can be administered by non-MDs as a reliable measure for collecting standardized information regarding antidepressant treatment history via patient interview.
authors.affiliation: Department of Psychiatry and Human Behavior, Brown University School of Medicine, Rhode Island Hospital, Providence, USA.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Posternak
authors.forename: Diane
authors.initials: D
authors.lastname: Young
authors.forename: Thomas
authors.initials: T
authors.lastname: Sheeran
authors.forename: Iwona
authors.initials: I
authors.lastname: Chelminski
authors.forename: C Laurel
authors.initials: CL
authors.lastname: Franklin
authors.forename: Mark
authors.initials: M
authors.lastname: Zimmerman
mesh_terms: D000328:Adult; D000368:Aged; D000928:Antidepressive Agents / Q000145:classification / Q000627:therapeutic use*; D002986:Clinical Trials as Topic / Q000706:statistics & numerical data; D015331:Cohort Studies; D003866:Depressive Disorder / Q000188:drug therapy* / Q000453:epidemiology; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D008297:Male; D008605:Mental Health Services / Q000592:standards; D008875:Middle Aged; D015588:Observer Variation; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents