[Basic research and clinical application of cartilage-derived retinoic acid-sensitive protein].
OBJECTIVE
To know the basic research and the clinical application of cartilage-derived retinoic acid-sensitive protein (CD-RAP) in orthopedic and in other clinical fields.


METHODS
The literature related to CD-RAP in basic research and clinical application were extensively reviewed.


RESULTS
CD-RAP, as a protein, which is cartilage-specific, could be a marker of the joint diseases. It also can be used to monitor metastasis of melanoma.


CONCLUSIONS
CD-RAP test provides a new way to study repair of cartilage and metastasis of melanoma.
Liu
Yang
Y
Department of Orthopedics, West China Hospital, Sichuan University, Chegndu, Sichuan, P. R. China 610041.
Yang
Tian-fu
TF
D015415:Biomarkers; D002358:Cartilage, Articular / Q000378:metabolism; D007124:Immunoenzyme Techniques; D008545:Melanoma / Q000378:metabolism; D014176:Protein Biosynthesis; D011506:Proteins / Q000032:analysis / Q000235:genetics
D015415:Biomarkers; D011506:Proteins