Retinal vasculitis due to secondary syphilis.
BACKGROUND
Retinal vasculitis is one of the manifestations of ocular syphilis.


METHODS
A 29-year-old man was referred to our hospital with the complaint of sudden visual loss in the left eye lasting more than three weeks.


METHODS
Ophthalmoscopic examination showed retinal hemorrhages, edema, and sheathing of large retinal arteries and veins. Fluorescein angiography revealed extensive occlusion of the affected retinal arteries, veins, and capillaries. Little evidence of uveitis or vitritis was observed. The fluorescent treponemal antibody-absorption test was positive, and the Treponema pallidum hemagglutination titer was 1:10,240. The treatment with penicillin was effective, leading to resolution of the retinal hemorrhages and edema, although occlusion of the retinal vessels persisted.


CONCLUSIONS
Vascular occlusion occurred simultaneously in large retinal arteries, arterioles, and capillaries as well as in segments of retinal veins, resulting in irreversible changes in the vascular walls.
Yokoi
Masahiko
M
Department of Ophthalmology, Teine Keijin-kai Hospital, Sapporo, Japan.
Kase
Manabu
M
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D015818:Eye Infections, Bacterial / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005451:Fluorescein Angiography; D016508:Fluorescent Treponemal Antibody-Absorption Test; D006801:Humans; D008297:Male; D010211:Papilledema / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D010400:Penicillin G / Q000627:therapeutic use; D012161:Retinal Artery / Q000473:pathology; D012166:Retinal Hemorrhage / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D031300:Retinal Vasculitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D012169:Retinal Vein / Q000473:pathology; D013587:Syphilis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D010400:Penicillin G