title: Pharmacobezoar complicating treatment with sodium alginate.
abstract: We encountered a gastric bezoar that had developed in a 9-year-old girl treated with sodium alginate (Alloid G) for acute gastritis associated with systemic lupus erythematosus. A hard mass palpated in the left upper abdomen proved, upon gastric endoscopy, to be an intragastric foreign body. Sodium alginate was detected in an analysis of a sample from this bezoar. In an in vitro simulation, sodium alginate solidified when mixed with the patient's other medicines. The bezoar caused no complications, and disappeared spontaneously after discontinuation of the medications. This case indicates that this sodium alginate preparation, Alloid G, can be a cause of pharmacobezoar.
authors.affiliation: Department of Pediatrics, Gunma University School of Medicine, 3-39-15 Showa-machi, Maebashi 371-8511, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kaneko
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tomomasa
authors.forename: Yumi
authors.initials: Y
authors.lastname: Kubota
authors.forename: Makoto
authors.initials: M
authors.lastname: Todokoro
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kato
authors.forename: Reiko
authors.initials: R
authors.lastname: Miyazawa
authors.forename: Tomoko
authors.initials: T
authors.lastname: Suzuki
authors.forename: Yukie
authors.initials: Y
authors.lastname: Hatori
authors.forename: Fumio
authors.initials: F
authors.lastname: Kunimoto
authors.forename: Koujirou
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Akihiro
authors.initials: A
authors.lastname: Morikawa
mesh_terms: D000464:Alginates / Q000009:adverse effects* / Q000627:therapeutic use; D001630:Bezoars; D002648:Child; D005260:Female; D005756:Gastritis / Q000188:drug therapy; D020723:Glucuronic Acid / Q000009:adverse effects* / Q000627:therapeutic use; D006490:Hemostatics / Q000009:adverse effects* / Q000627:therapeutic use; D006603:Hexuronic Acids / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D013270:Stomach
chemical_list: D000464:Alginates; D006490:Hemostatics; D006603:Hexuronic Acids; D020723:Glucuronic Acid