Congenital infantile hepatic hemangioendothelioma type II treated with orthotopic liver transplantation.
The authors describe a 10-week-old girl with infantile hepatic hemangioendothelioma who initially presented with difficulty feeding, hepatomegaly, and multiple hemangiomas of the skin. Six weeks of steroid therapy and 2 weeks of chemotherapy failed to produce clinical improvement. The patient underwent split liver transplantation. A definitive diagnosis of hemangioendothelioma type II was made. Imaging studies cannot differentiate between hemangioendothelioma and angiosarcoma. Treatment modalities for this condition remain unclear. The patient continues to do well.
Walsh
Rowan
R
Department of Pediatrics, Children's Hospital at Westchester Medical Center, New York Medical College, Valhalla, New York, USA.
Harrington
John
J
Beneck
Debra
D
Ozkaynak
M Fevzi
MF
D005260:Female; D006390:Hemangioendothelioma / Q000151:congenital* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000151:congenital* / Q000473:pathology / Q000601:surgery*; D016031:Liver Transplantation; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome