title: Disclosing new inhibitors by finding similarities in three-dimensional active-site architectures of polynuclear zinc phospholipases and aminopeptidases.
authors.affiliation: RUBAM, Department of Biological Organic Chemistry (IIQAB-CSIC), Jordi Girona 18-26, 08034-Barcelona, Spain.
authors.forename: Albert
authors.initials: A
authors.lastname: González-Roura
authors.forename: Isabel
authors.initials: I
authors.lastname: Navarro
authors.forename: Antonio
authors.initials: A
authors.lastname: Delgado
authors.forename: Amadeu
authors.initials: A
authors.lastname: Llebaria
authors.forename: Josefina
authors.initials: J
authors.lastname: Casas
mesh_terms: D000626:Aminopeptidases / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000378:metabolism; D001665:Binding Sites; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D007700:Kinetics; D008666:Metalloendopeptidases / Q000737:chemistry / Q000378:metabolism; D008958:Models, Molecular; D010740:Phospholipases / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000378:metabolism; D011487:Protein Conformation; D013379:Substrate Specificity; D015032:Zinc / Q000737:chemistry*
chemical_list: D004791:Enzyme Inhibitors; D010740:Phospholipases; D000626:Aminopeptidases; D008666:Metalloendopeptidases; D015032:Zinc