Long-term treatment with cyclosporine decreases aquaporins and urea transporters in the rat kidney.
D000818:Animals; D020346:Aquaporins / Q000032:analysis / Q000096:biosynthesis* / Q000494:pharmacology; D016572:Cyclosporine / Q000008:administration & dosage / Q000009:adverse effects* / Q000494:pharmacology*; D004334:Drug Administration Schedule; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000494:pharmacology*; D020287:In Situ Nick-End Labeling; D007668:Kidney / Q000187:drug effects / Q000502:physiology*; D008297:Male; D026901:Membrane Transport Proteins / Q000032:analysis / Q000096:biosynthesis* / Q000494:pharmacology; D051381:Rats; D017207:Rats, Sprague-Dawley; D000254:Sodium-Potassium-Exchanging ATPase / Q000494:pharmacology; D014667:Vasopressins / Q000097:blood; D000096982:Urea Transporters
D020346:Aquaporins; D016572:Cyclosporine; D007166:Immunosuppressive Agents; D026901:Membrane Transport Proteins; D000254:Sodium-Potassium-Exchanging ATPase; D014667:Vasopressins; D000096982:Urea Transporters