Protease inhibitors modulate apoptosis in mesangial cells derived from a mouse model of HIVAN.
D016263:AIDS-Associated Nephropathy / Q000188:drug therapy* / Q000473:pathology*; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects; D002478:Cells, Cultured; D004195:Disease Models, Animal; D016166:Free Radical Scavengers / Q000494:pharmacology; D015870:Gene Expression / Q000187:drug effects; D005920:Glomerular Mesangium / Q000166:cytology / Q000187:drug effects / Q000201:enzymology; D017320:HIV Protease Inhibitors / Q000494:pharmacology*; D015497:HIV-1 / Q000235:genetics*; D006419:Heme Oxygenase (Decyclizing) / Q000235:genetics / Q000378:metabolism; D051547:Heme Oxygenase-1; D006861:Hydrogen Peroxide / Q000378:metabolism; D008297:Male; D008565:Membrane Proteins; D051379:Mice; D008815:Mice, Inbred Strains; D008822:Mice, Transgenic; D009020:Morphine / Q000494:pharmacology; D019255:NADPH Oxidases / Q000378:metabolism; D009294:Narcotics / Q000494:pharmacology; D018384:Oxidative Stress / Q000187:drug effects; D019258:Saquinavir / Q000494:pharmacology*; D013482:Superoxide Dismutase / Q000378:metabolism; D013481:Superoxides / Q000378:metabolism
D000975:Antioxidants; D016166:Free Radical Scavengers; D017320:HIV Protease Inhibitors; D008565:Membrane Proteins; D009294:Narcotics; D013481:Superoxides; D009020:Morphine; D006861:Hydrogen Peroxide; D006419:Heme Oxygenase (Decyclizing); D051547:Heme Oxygenase-1; C496542:Hmox1 protein, mouse; D013482:Superoxide Dismutase; D019255:NADPH Oxidases; D019258:Saquinavir