Identification of the substrate-binding exosites of two snake venom serine proteinases: molecular basis for the partition of two essential functions of thrombin.
D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D017837:Bothrops; D003435:Crotalid Venoms / Q000737:chemistry* / Q000201:enzymology* / Q000378:metabolism*; D019143:Evolution, Molecular; D005340:Fibrinogen / Q000737:chemistry / Q000378:metabolism; D046911:Macromolecular Substances; D008958:Models, Molecular; D008969:Molecular Sequence Data; D018583:Pliability; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D020539:Sequence Analysis, Protein; D012697:Serine Endopeptidases / Q000737:chemistry* / Q000378:metabolism*; D015842:Serine Proteinase Inhibitors / Q000737:chemistry / Q000378:metabolism; D055672:Static Electricity; D013329:Structure-Activity Relationship; D013379:Substrate Specificity; D013917:Thrombin / Q000737:chemistry / Q000378:metabolism
D003435:Crotalid Venoms; D046911:Macromolecular Substances; D015842:Serine Proteinase Inhibitors; D005340:Fibrinogen; C038929:Bothrops jararaca protease A; D012697:Serine Endopeptidases; C086027:bothrombin; D013917:Thrombin; C019948:crotalase