Basic fibroblast growth factor mediates transduction of mechanical signals when articular cartilage is loaded.
D000818:Animals; D015153:Blotting, Western; D002358:Cartilage, Articular / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D019902:Chondrocytes / Q000187:drug effects / Q000378:metabolism; D016222:Fibroblast Growth Factor 2 / Q000378:metabolism*; D066298:In Vitro Techniques; D020928:Mitogen-Activated Protein Kinases / Q000096:biosynthesis; D011743:Pyrimidines / Q000494:pharmacology; D017468:Receptors, Fibroblast Growth Factor / Q000037:antagonists & inhibitors; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology*; D013264:Stifle / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D013314:Stress, Mechanical; D013552:Swine; D019715:Tissue Inhibitor of Metalloproteinase-1 / Q000096:biosynthesis / Q000378:metabolism; D016474:Weight-Bearing
C115711:PD 173074; D011743:Pyrimidines; D017468:Receptors, Fibroblast Growth Factor; D019715:Tissue Inhibitor of Metalloproteinase-1; D016222:Fibroblast Growth Factor 2; D020928:Mitogen-Activated Protein Kinases