A genome-wide screen in Saccharomyces cerevisiae reveals altered transport as a mechanism of resistance to the anticancer drug bleomycin.
D026905:Amino Acid Transport Systems / Q000096:biosynthesis / Q000235:genetics; D000964:Antimetabolites, Antineoplastic / Q000493:pharmacokinetics / Q000494:pharmacology*; D001692:Biological Transport; D001761:Bleomycin / Q000493:pharmacokinetics / Q000494:pharmacology*; D004249:DNA Damage; D019008:Drug Resistance, Neoplasm; D016681:Genome, Fungal; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins / Q000096:biosynthesis / Q000235:genetics; D027981:Symporters / Q000096:biosynthesis / Q000235:genetics
C402286:Agp2 protein, S cerevisiae; D026905:Amino Acid Transport Systems; D000964:Antimetabolites, Antineoplastic; D029701:Saccharomyces cerevisiae Proteins; D027981:Symporters; D001761:Bleomycin