Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol.
D000970:Antineoplastic Agents / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D002455:Cell Division / Q000187:drug effects; D045744:Cell Line, Tumor; D002722:Chlorobenzenes / Q000494:pharmacology*; D015536:Down-Regulation / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D004983:Ethanolamines / Q000494:pharmacology*; D005347:Fibroblasts / Q000187:drug effects; D006801:Humans; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000096:biosynthesis* / Q000235:genetics; D014162:Transfection; D051020:bcl-X Protein
C483320:2-((3-(2,3-dichlorophenoxy)propyl)amino)ethanol; D000970:Antineoplastic Agents; C494811:BCL2L1 protein, human; D002722:Chlorobenzenes; D004983:Ethanolamines; D019253:Proto-Oncogene Proteins c-bcl-2; D051020:bcl-X Protein