A founder mutation of the MSH2 gene and hereditary nonpolyposis colorectal cancer in the United States.
D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000453:epidemiology* / Q000235:genetics*; D004252:DNA Mutational Analysis; D004268:DNA-Binding Proteins; D005260:Female; D018703:Founder Effect; D017353:Gene Deletion; D005820:Genetic Testing; D006239:Haplotypes; D006801:Humans; D008297:Male; D051718:MutS Homolog 2 Protein; D009154:Mutation; D010375:Pedigree; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D014481:United States / Q000453:epidemiology; D044465:White People / Q000235:genetics
D004268:DNA-Binding Proteins; D011518:Proto-Oncogene Proteins; C497172:MSH2 protein, human; D051718:MutS Homolog 2 Protein