Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stress.
D000447:Aldehydes / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology; D001980:Bronchi / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D004848:Epithelium / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D005721:Glutamate-Cysteine Ligase / Q000187:drug effects / Q000378:metabolism*; D005978:Glutathione / Q000096:biosynthesis* / Q000187:drug effects; D006801:Humans; D006873:Hydroquinones / Q000494:pharmacology; D009285:Naphthoquinones / Q000494:pharmacology; D018384:Oxidative Stress / Q000187:drug effects / Q000502:physiology*
D000447:Aldehydes; D000975:Antioxidants; D006873:Hydroquinones; D009285:Naphthoquinones; C462359:tert-4-hydroxy-2-nonenal; C063002:2,3-dimethoxy-1,4-naphthoquinone; C018855:2-tert-butylhydroquinone; D005721:Glutamate-Cysteine Ligase; D005978:Glutathione