Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro.
D019883:Alkyl and Aryl Transferases / Q000037:antagonists & inhibitors; D002455:Cell Division / Q000187:drug effects*; D004164:Diphosphonates / Q000494:pharmacology*; D051228:Geranyltranstransferase; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology*; D066298:In Vitro Techniques; D008213:Lymphocyte Activation / Q000187:drug effects*; D008798:Mevalonic Acid / Q000494:pharmacology; D017368:Protein Prenylation; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000032:analysis*; D013601:T-Lymphocytes / Q000166:cytology / Q000187:drug effects* / Q000201:enzymology / Q000276:immunology
D004164:Diphosphonates; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D016692:Receptors, Antigen, T-Cell, gamma-delta; D019883:Alkyl and Aryl Transferases; D051228:Geranyltranstransferase; D008798:Mevalonic Acid