Cell volume regulation in response to hypotonicity is impaired in HeLa cells expressing a protein kinase Calpha mutant lacking kinase activity.
D015153:Blotting, Western; D002118:Calcium / Q000378:metabolism; D000252:Calcium-Transporting ATPases / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism; D048429:Cell Size; D002614:Chelating Agents / Q000494:pharmacology; D003599:Cytoskeleton / Q000378:metabolism; D003600:Cytosol / Q000378:metabolism; D015536:Down-Regulation; D004533:Egtazic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology; D004721:Endoplasmic Reticulum / Q000378:metabolism; D005799:Genes, Dominant; D049452:Green Fluorescent Proteins; D006367:HeLa Cells; D006801:Humans; D007527:Isoenzymes; D008164:Luminescent Proteins / Q000378:metabolism; D009154:Mutation; D011493:Protein Kinase C / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D051571:Protein Kinase C-alpha; D021381:Protein Transport; D013347:Subcellular Fractions / Q000378:metabolism; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D019284:Thapsigargin / Q000494:pharmacology; D013997:Time Factors; D014162:Transfection; D000099221:Protein Kinase C zeta
D002118:Calcium; D000252:Calcium-Transporting ATPases; D002614:Chelating Agents; D004533:Egtazic Acid; D049452:Green Fluorescent Proteins; D007527:Isoenzymes; D008164:Luminescent Proteins; D011493:Protein Kinase C; D051571:Protein Kinase C-alpha; D013755:Tetradecanoylphorbol Acetate; D019284:Thapsigargin; D000099221:Protein Kinase C zeta; C070379:1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester; C496628:PRKCA protein, human