Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signalling.
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D019556:COS Cells; D002522:Chlorocebus aethiops; D005260:Female; D005347:Fibroblasts / Q000378:metabolism; D037502:Galectin 3 / Q000096:biosynthesis* / Q000235:genetics; D005837:Genitalia, Male / Q000378:metabolism / Q000473:pathology; D007249:Inflammation / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D008297:Male; D008565:Membrane Proteins / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D051379:Mice; D018345:Mice, Knockout; D009206:Myocardium / Q000378:metabolism; D016328:NF-kappa B / Q000037:antagonists & inhibitors*; D009928:Organ Specificity; D010053:Ovary / Q000378:metabolism; D025941:Protein Interaction Mapping; D012333:RNA, Messenger / Q000096:biosynthesis; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D013737:Testis / Q000378:metabolism; D014158:Transcription, Genetic; D014162:Transfection; D020798:Two-Hybrid System Techniques
D037502:Galectin 3; D008565:Membrane Proteins; D016328:NF-kappa B; D012333:RNA, Messenger; D011993:Recombinant Fusion Proteins; C483107:Uaca protein, mouse