Organ injury and cytokine release caused by peptidoglycan are dependent on the structural integrity of the glycan chain.
D000192:Actinomycetales / Q000737:chemistry / Q000472:pathogenicity; D000818:Animals; D001412:Bacillus subtilis / Q000737:chemistry / Q000472:pathogenicity; D016207:Cytokines / Q000096:biosynthesis* / Q000097:blood; D006801:Humans; D006868:Hydrolysis; D066298:In Vitro Techniques; D018836:Inflammation Mediators / Q000097:blood; D008297:Male; D015394:Molecular Structure; D009102:Multiple Organ Failure / Q000209:etiology*; D010455:Peptides / Q000737:chemistry; D010457:Peptidoglycan / Q000737:chemistry* / Q000633:toxicity*; D011134:Polysaccharides / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D013211:Staphylococcus aureus / Q000737:chemistry / Q000472:pathogenicity
D016207:Cytokines; D018836:Inflammation Mediators; D010455:Peptides; D010457:Peptidoglycan; D011134:Polysaccharides