Opioid-induced cardioprotection occurs via glycogen synthase kinase beta inhibition during reperfusion in intact rat hearts.
D000627:Aminophenols / Q000494:pharmacology; D000730:Androstadienes / Q000494:pharmacology; D000818:Animals; D001549:Benzamides / Q000494:pharmacology*; D002316:Cardiotonic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002867:Chromones / Q000494:pharmacology; D038362:Glycogen Synthase Kinase 3 / Q000037:antagonists & inhibitors* / Q000502:physiology; D000071679:Glycogen Synthase Kinase 3 beta; D007211:Indoles / Q000494:pharmacology; D008297:Male; D008301:Maleimides / Q000494:pharmacology; D009020:Morphine / Q000494:pharmacology*; D009025:Morpholines / Q000494:pharmacology; D009203:Myocardial Infarction / Q000378:metabolism / Q000473:pathology*; D009292:Narcotic Antagonists / Q000494:pharmacology; D057132:Nuclear Receptor Subfamily 1, Group F, Member 3; D019869:Phosphatidylinositol 3-Kinases / Q000502:physiology; D000081082:Phosphoinositide-3 Kinase Inhibitors; D010879:Piperazines / Q000494:pharmacology*; D011292:Premedication; D051381:Rats; D017207:Rats, Sprague-Dawley; D017465:Receptors, Opioid, delta / Q000187:drug effects; D018168:Receptors, Retinoic Acid / Q000037:antagonists & inhibitors / Q000502:physiology; D011988:Receptors, Thyroid Hormone / Q000037:antagonists & inhibitors / Q000502:physiology; D015398:Signal Transduction / Q000187:drug effects; D020123:Sirolimus / Q000494:pharmacology; D000077191:Wortmannin
D000627:Aminophenols; D000730:Androstadienes; D001549:Benzamides; D002316:Cardiotonic Agents; D002867:Chromones; D038362:Glycogen Synthase Kinase 3; D000071679:Glycogen Synthase Kinase 3 beta; D007211:Indoles; D008301:Maleimides; D009020:Morphine; D009025:Morpholines; D009292:Narcotic Antagonists; D057132:Nuclear Receptor Subfamily 1, Group F, Member 3; D019869:Phosphatidylinositol 3-Kinases; D000081082:Phosphoinositide-3 Kinase Inhibitors; D010879:Piperazines; D017465:Receptors, Opioid, delta; D018168:Receptors, Retinoic Acid; D011988:Receptors, Thyroid Hormone; D020123:Sirolimus; D000077191:Wortmannin; C417520:3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione; C539902:Rorc protein, rat; C417521:SB 216763; C083877:BW 373U86; C085911:2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one