title: Lead-induced cytotoxicity and transcriptional activation of stress genes in human liver carcinoma (HepG2) cells.
mesh_terms: D019677:Artificial Gene Fusion; D002455:Cell Division / Q000187:drug effects; D015500:Chloramphenicol O-Acetyltransferase / Q000235:genetics / Q000378:metabolism; D000091342:Endoplasmic Reticulum Chaperone BiP; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects*; D006801:Humans; D007854:Lead / Q000378:metabolism / Q000494:pharmacology* / Q000633:toxicity*; D008113:Liver Neoplasms / Q000235:genetics / Q000378:metabolism; D009566:Nitrates / Q000494:pharmacology*; D011401:Promoter Regions, Genetic / Q000235:genetics; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects; D015533:Transcriptional Activation / Q000187:drug effects*; D014407:Tumor Cells, Cultured
chemical_list: D000091342:Endoplasmic Reticulum Chaperone BiP; C000717247:HSPA5 protein, human; D009566:Nitrates; D011994:Recombinant Proteins; D007854:Lead; C017461:lead nitrate; D015500:Chloramphenicol O-Acetyltransferase