Mice with reduced brain-derived neurotrophic factor expression show decreased choline acetyltransferase activity, but regular brain monoamine levels and unaltered emotional behavior.
D000324:Adrenocorticotropic Hormone / Q000097:blood; D000704:Analysis of Variance; D000818:Animals; D001007:Anxiety; D015306:Biogenic Monoamines / Q000378:metabolism*; D001921:Brain / Q000033:anatomy & histology / Q000201:enzymology* / Q000378:metabolism; D001923:Brain Chemistry; D019208:Brain-Derived Neurotrophic Factor / Q000235:genetics / Q000378:metabolism*; D002795:Choline O-Acetyltransferase / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D003214:Conditioning, Classical / Q000502:physiology; D004563:Electrochemistry / Q000379:methods; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005106:Exploratory Behavior / Q000502:physiology; D005239:Fear / Q000502:physiology; D008297:Male; D018782:Maze Learning / Q000502:physiology; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D009043:Motor Activity / Q000502:physiology; D020932:Nerve Growth Factor / Q000032:analysis; D011597:Psychomotor Performance / Q000502:physiology*; D011930:Reaction Time; D013312:Stress, Physiological
D015306:Biogenic Monoamines; D019208:Brain-Derived Neurotrophic Factor; D000324:Adrenocorticotropic Hormone; D020932:Nerve Growth Factor; D002795:Choline O-Acetyltransferase