Redox state-dependent and sorbitol accumulation-independent diabetic albuminuria in mice with transgene-derived human aldose reductase and sorbitol dehydrogenase deficiency.
D000419:Albuminuria; D000449:Aldehyde Reductase / Q000235:genetics* / Q000378:metabolism; D000818:Animals; D003928:Diabetic Nephropathies / Q000652:urine*; D006801:Humans; D007064:L-Iditol 2-Dehydrogenase / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D010084:Oxidation-Reduction; D013012:Sorbitol / Q000378:metabolism*
D013012:Sorbitol; D007064:L-Iditol 2-Dehydrogenase; D000449:Aldehyde Reductase