Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism.
D000818:Animals; D002118:Calcium / Q000097:blood; D005260:Female; D005269:Femur / Q000166:cytology / Q000378:metabolism / Q000473:pathology; D000089703:Fibroblast Growth Factor-23; D005346:Fibroblast Growth Factors / Q000235:genetics / Q000378:metabolism*; D018390:Gene Targeting; D007684:Kidney Tubules / Q000166:cytology / Q000378:metabolism; D008297:Male; D051379:Mice; D018345:Mice, Knockout; D010281:Parathyroid Hormone / Q000097:blood; D010710:Phosphates / Q000097:blood*; D014807:Vitamin D / Q000097:blood*
C000717428:Fgf23 protein, mouse; D010281:Parathyroid Hormone; D010710:Phosphates; D014807:Vitamin D; D005346:Fibroblast Growth Factors; D000089703:Fibroblast Growth Factor-23; D002118:Calcium