Reduced MGMT activity in human colorectal adenomas is associated with K-ras GC->AT transition mutations in a population exposed to methylating agents.
D000236:Adenoma / Q000201:enzymology*; D019883:Alkyl and Aryl Transferases / Q000378:metabolism*; D015179:Colorectal Neoplasms / Q000201:enzymology*; D019175:DNA Methylation; D011905:Genes, ras; D006147:Guanine / Q000031:analogs & derivatives / Q000378:metabolism; D006801:Humans; D009154:Mutation
D006147:Guanine; C008450:7-methylguanine; D019883:Alkyl and Aryl Transferases; C050956:DNA alkyltransferase