title: Loss of the tumor suppressor PML in human cancers of multiple histologic origins.
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics; D000306:Adrenal Cortex Neoplasms / Q000235:genetics; D015152:Blotting, Northern; D001943:Breast Neoplasms / Q000235:genetics; D002277:Carcinoma / Q000235:genetics* / Q000473:pathology; D016543:Central Nervous System Neoplasms / Q000235:genetics; D003110:Colonic Neoplasms / Q000235:genetics; D017931:DNA Primers; D005260:Female; D005455:Fluorescent Antibody Technique; D015972:Gene Expression Regulation, Neoplastic; D018237:Germinoma / Q000235:genetics; D006801:Humans; D019656:Loss of Heterozygosity; D008175:Lung Neoplasms / Q000235:genetics; D008297:Male; D009154:Mutation; D009363:Neoplasm Proteins / Q000235:genetics*; D009367:Neoplasm Staging; D009687:Nuclear Proteins; D016133:Polymerase Chain Reaction; D000071156:Promyelocytic Leukemia Protein; D011471:Prostatic Neoplasms / Q000235:genetics; D040081:Protein Array Analysis; D012333:RNA, Messenger / Q000378:metabolism; D018168:Receptors, Retinoic Acid / Q000235:genetics*; D000072482:Retinoic Acid Receptor alpha; D013964:Thyroid Neoplasms / Q000235:genetics; D014157:Transcription Factors / Q000235:genetics*; D025521:Tumor Suppressor Proteins
chemical_list: D017931:DNA Primers; D009363:Neoplasm Proteins; D009687:Nuclear Proteins; D000071156:Promyelocytic Leukemia Protein; C000607071:RARA protein, human; D012333:RNA, Messenger; D018168:Receptors, Retinoic Acid; D000072482:Retinoic Acid Receptor alpha; D014157:Transcription Factors; D025521:Tumor Suppressor Proteins; C070576:PML protein, human