In vitro sulfoxidation of thioether compounds by human cytochrome P450 and flavin-containing monooxygenase isoforms with particular reference to the CYP2C subfamily.
D001189:Aryl Hydrocarbon Hydroxylases / Q000037:antagonists & inhibitors; D002384:Catalysis; D002851:Chromatography, High Pressure Liquid; D065731:Cytochrome P-450 CYP2C19; D065729:Cytochrome P-450 CYP2C9; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D007527:Isoenzymes / Q000378:metabolism; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors; D008995:Monoamine Oxidase / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet; D013329:Structure-Activity Relationship; D013426:Sulfaphenazole / Q000494:pharmacology; D013440:Sulfides / Q000378:metabolism*; D013454:Sulfoxides / Q000378:metabolism*; D013988:Ticlopidine / Q000494:pharmacology
D004791:Enzyme Inhibitors; D007527:Isoenzymes; D013440:Sulfides; D013454:Sulfoxides; C400322:cytochrome P-450 CYP2C subfamily; D013426:Sulfaphenazole; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; C450260:CYP2C9 protein, human; D065729:Cytochrome P-450 CYP2C9; D001189:Aryl Hydrocarbon Hydroxylases; C045793:CYP2C19 protein, human; D065731:Cytochrome P-450 CYP2C19; D008995:Monoamine Oxidase; D013988:Ticlopidine