Structure-activity relationships of small phosphopeptides, inhibitors of Grb2 SH2 domain, and their prodrugs.
D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001667:Binding, Competitive; D045744:Cell Line, Tumor; D002471:Cell Transformation, Neoplastic; D004952:Esters / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D051380:GRB2 Adaptor Protein; D006801:Humans; D051379:Mice; D018716:Molecular Mimicry; D041681:NIH 3T3 Cells; D010748:Phosphopeptides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D019000:Phosphotyrosine / Q000737:chemistry*; D011355:Prodrugs / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011506:Proteins / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000378:metabolism*; D013329:Structure-Activity Relationship; D018909:src Homology Domains
D048868:Adaptor Proteins, Signal Transducing; D000970:Antineoplastic Agents; D004952:Esters; D051380:GRB2 Adaptor Protein; D010748:Phosphopeptides; D019000:Phosphotyrosine; D011355:Prodrugs; D011506:Proteins; D018719:Erb-b2 Receptor Tyrosine Kinases; C495948:GRB2 protein, human; C495949:Grb2 protein, mouse