title: Remifentanil by bolus injection: a safety, pharmacokinetic, pharmacodynamic, and age effect investigation in human volunteers.
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging / Q000097:blood; D000701:Analgesics, Opioid / Q000009:adverse effects / Q000097:blood / Q000494:pharmacology*; D018686:Anesthetics, Intravenous / Q000009:adverse effects / Q000097:blood / Q000494:pharmacology*; D003198:Computer Simulation; D018592:Cross-Over Studies; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D010880:Piperidines / Q000009:adverse effects / Q000097:blood / Q000494:pharmacology*; D000077208:Remifentanil; D012131:Respiratory Insufficiency / Q000139:chemically induced
chemical_list: D000701:Analgesics, Opioid; D018686:Anesthetics, Intravenous; D010880:Piperidines; D000077208:Remifentanil