title: Enhanced rat Hershberger assay appears reliable for detection of not only (anti-)androgenic chemicals but also thyroid hormone modulators.
mesh_terms: D000284:Administration, Oral; D000726:Androgen Antagonists / Q000737:chemistry*; D000818:Animals; D013956:Antithyroid Agents / Q000737:chemistry*; D001835:Body Weight / Q000187:drug effects; D002369:Castration / Q000379:methods; D003633:Dichlorodiphenyl Dichloroethylene / Q000008:administration & dosage / Q000493:pharmacokinetics; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D004435:Eating / Q000187:drug effects; D007279:Injections, Subcutaneous; D008297:Male; D009929:Organ Size / Q000187:drug effects; D010634:Phenobarbital / Q000008:administration & dosage / Q000493:pharmacokinetics; D011441:Propylthiouracil / Q000008:administration & dosage / Q000493:pharmacokinetics; D051381:Rats; D011919:Rats, Inbred Strains; D015203:Reproducibility of Results; D043343:Testosterone Propionate / Q000008:administration & dosage / Q000493:pharmacokinetics; D013961:Thyroid Gland / Q000187:drug effects / Q000473:pathology; D013972:Thyrotropin / Q000097:blood / Q000187:drug effects; D013974:Thyroxine / Q000097:blood / Q000187:drug effects; D014284:Triiodothyronine / Q000097:blood / Q000187:drug effects
chemical_list: D000726:Androgen Antagonists; D013956:Antithyroid Agents; D014284:Triiodothyronine; D003633:Dichlorodiphenyl Dichloroethylene; D011441:Propylthiouracil; D013972:Thyrotropin; D013974:Thyroxine; D043343:Testosterone Propionate; D010634:Phenobarbital