In vitro and in vivo cytotoxic activities of recombinant immunotoxin 8H9(Fv)-PE38 against breast cancer, osteosarcoma, and neuroblastoma.
D036002:ADP Ribose Transferases / Q000097:blood / Q000627:therapeutic use*; D000818:Animals; D000911:Antibodies, Monoclonal / Q000097:blood / Q000627:therapeutic use*; D001427:Bacterial Toxins / Q000097:blood / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy*; D001943:Breast Neoplasms / Q000188:drug therapy*; D045744:Cell Line, Tumor; D005098:Exotoxins / Q000097:blood / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007128:Immunoglobulin Fragments / Q000627:therapeutic use*; D000922:Immunotoxins / Q000097:blood / Q000627:therapeutic use*; D008252:Macaca fascicularis; D051379:Mice; D016513:Mice, SCID; D009447:Neuroblastoma / Q000188:drug therapy*; D012516:Osteosarcoma / Q000188:drug therapy*; D011993:Recombinant Fusion Proteins / Q000097:blood / Q000627:therapeutic use*; D037521:Virulence Factors / Q000097:blood / Q000627:therapeutic use*; D000097668:Pseudomonas aeruginosa Exotoxin A
D036002:ADP Ribose Transferases; D000911:Antibodies, Monoclonal; D001427:Bacterial Toxins; D005098:Exotoxins; D007128:Immunoglobulin Fragments; D000922:Immunotoxins; D011993:Recombinant Fusion Proteins; D037521:Virulence Factors; D000097668:Pseudomonas aeruginosa Exotoxin A; C055966:immunoglobulin Fv