The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies.
D042702:Angiopoietin-2 / Q000235:genetics / Q000378:metabolism*; D002273:Carcinogens / Q000494:pharmacology; D002478:Cells, Cultured; D004730:Endothelium, Vascular / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D015870:Gene Expression; D006801:Humans; D008024:Ligands; D009131:Muscle, Smooth, Vascular / Q000166:cytology; D019007:P-Selectin / Q000378:metabolism; D042787:Receptor, TIE-2 / Q000378:metabolism*; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D014469:Umbilical Arteries / Q000166:cytology; D014471:Umbilical Veins / Q000166:cytology; D020302:Weibel-Palade Bodies / Q000378:metabolism*
D042702:Angiopoietin-2; D002273:Carcinogens; D008024:Ligands; D019007:P-Selectin; D042787:Receptor, TIE-2; D013755:Tetradecanoylphorbol Acetate