title: Positive selection at reproductive ADAM genes with potential intercellular binding activity.
mesh_terms: D051722:ADAM Proteins; D000072197:ADAM10 Protein; D053829:Amyloid Precursor Protein Secretases; D000818:Animals; D001665:Binding Sites; D019070:Cell Lineage; D002462:Cell Membrane / Q000378:metabolism; D003062:Codon; D003545:Cysteine / Q000737:chemistry; D003600:Cytosol / Q000378:metabolism; D019483:Disintegrins / Q000737:chemistry; D005306:Fertilization; D006801:Humans; D008024:Ligands; D008562:Membrane Glycoproteins / Q000235:genetics; D008565:Membrane Proteins / Q000235:genetics* / Q000378:metabolism*; D008666:Metalloendopeptidases / Q000235:genetics / Q000378:metabolism; D051379:Mice; D008957:Models, Genetic; D005810:Multigene Family; D010802:Phylogeny; D011485:Protein Binding; D011506:Proteins / Q000235:genetics; D012641:Selection, Genetic; D013091:Spermatogenesis; D014018:Tissue Distribution
chemical_list: D003062:Codon; D019483:Disintegrins; D008024:Ligands; D008562:Membrane Glycoproteins; D008565:Membrane Proteins; D011506:Proteins; D053829:Amyloid Precursor Protein Secretases; D051722:ADAM Proteins; C484643:ADAM18 protein, human; C438783:ADAM7 protein, human; D008666:Metalloendopeptidases; D000072197:ADAM10 Protein; C491236:ADAM10 protein, human; D003545:Cysteine