title: Role of active-site residues Thr81, Ser82, Thr85, Gln157, and Tyr158 in yeast cystathionine beta-synthase catalysis and reaction specificity.
mesh_terms: D000409:Alanine / Q000235:genetics; D019943:Amino Acid Substitution / Q000235:genetics; D001665:Binding Sites / Q000235:genetics; D002384:Catalysis; D002846:Chromatography, Affinity; D003541:Cystathionine beta-Synthase / Q000737:chemistry* / Q000235:genetics; D005973:Glutamine / Q000737:chemistry* / Q000235:genetics; D007700:Kinetics; D008956:Models, Chemical; D016297:Mutagenesis, Site-Directed; D009532:Nickel; D010649:Phenylalanine / Q000235:genetics; D019289:Pyruvic Acid / Q000737:chemistry; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry* / Q000235:genetics; D012694:Serine / Q000737:chemistry* / Q000235:genetics; D013379:Substrate Specificity / Q000235:genetics; D013912:Threonine / Q000737:chemistry* / Q000235:genetics; D014443:Tyrosine / Q000737:chemistry* / Q000235:genetics
chemical_list: D029701:Saccharomyces cerevisiae Proteins; D005973:Glutamine; D013912:Threonine; D014443:Tyrosine; D012694:Serine; D010649:Phenylalanine; D009532:Nickel; D019289:Pyruvic Acid; D003541:Cystathionine beta-Synthase; D000409:Alanine