The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions.
D000595:Amino Acid Sequence; D000818:Animals; D001667:Binding, Competitive; D002453:Cell Cycle; D018797:Cell Cycle Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D045744:Cell Line, Tumor; D002642:Chick Embryo; D004247:DNA / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D024202:Electrophoretic Mobility Shift Assay; D016222:Fibroblast Growth Factor 2 / Q000235:genetics / Q000378:metabolism; D064248:Geminin; D018507:Gene Expression Regulation, Developmental; D018398:Homeodomain Proteins / Q000037:antagonists & inhibitors* / Q000235:genetics* / Q000378:metabolism; D051379:Mice; D008969:Molecular Sequence Data; D009687:Nuclear Proteins; D015513:Oncogene Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D063146:Polycomb-Group Proteins; D011485:Protein Binding; D012097:Repressor Proteins / Q000235:genetics* / Q000378:metabolism*; D020218:Response Elements / Q000235:genetics; D014158:Transcription, Genetic / Q000235:genetics
D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; D064248:Geminin; C577997:Gmnn protein, mouse; C491257:HOXB9 protein, human; D018398:Homeodomain Proteins; C104161:Hoxb9 protein, mouse; D009687:Nuclear Proteins; D015513:Oncogene Proteins; D063146:Polycomb-Group Proteins; D012097:Repressor Proteins; C487378:Tlx1 protein, mouse; D016222:Fibroblast Growth Factor 2; D004247:DNA