Dietary fish oil up-regulates cholesterol 7alpha-hydroxylase mRNA in mouse liver leading to an increase in bile acid and cholesterol excretion.
D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism*; D002784:Cholesterol / Q000378:metabolism*; D002790:Cholesterol 7-alpha-Hydroxylase / Q000235:genetics*; D004268:DNA-Binding Proteins; D004042:Dietary Fats, Unsaturated / Q000494:pharmacology*; D005395:Fish Oils / Q000494:pharmacology*; D008099:Liver / Q000201:enzymology / Q000378:metabolism; D000071518:Liver X Receptors; D051379:Mice; D009419:Nerve Tissue Proteins / Q000096:biosynthesis; D057093:Orphan Nuclear Receptors; D012333:RNA, Messenger / Q000096:biosynthesis; D016601:RNA-Binding Proteins / Q000096:biosynthesis; D018160:Receptors, Cytoplasmic and Nuclear / Q000096:biosynthesis; D015854:Up-Regulation / Q000187:drug effects
D001647:Bile Acids and Salts; D004268:DNA-Binding Proteins; D004042:Dietary Fats, Unsaturated; C467045:Drb1 protein, mouse; D005395:Fish Oils; D000071518:Liver X Receptors; D009419:Nerve Tissue Proteins; C000605214:Nr1h3 protein, mouse; D057093:Orphan Nuclear Receptors; D012333:RNA, Messenger; D016601:RNA-Binding Proteins; D018160:Receptors, Cytoplasmic and Nuclear; D002784:Cholesterol; D002790:Cholesterol 7-alpha-Hydroxylase