BAG-1 proteins protect cardiac myocytes from simulated ischemia/reperfusion-induced apoptosis via an alternate mechanism of cell survival independent of the proteasome.
D000818:Animals; D000831:Animals, Newborn; D017209:Apoptosis / Q000502:physiology*; D001483:Base Sequence; D002352:Carrier Proteins / Q000502:physiology*; D002470:Cell Survival / Q000502:physiology*; D003546:Cysteine Endopeptidases / Q000378:metabolism*; D017931:DNA Primers; D004268:DNA-Binding Proteins; D006801:Humans; D066298:In Vitro Techniques; D009097:Multienzyme Complexes / Q000378:metabolism*; D032342:Muscle Cells / Q000166:cytology / Q000502:physiology*; D015425:Myocardial Reperfusion; D015428:Myocardial Reperfusion Injury / Q000473:pathology / Q000517:prevention & control*; D046988:Proteasome Endopeptidase Complex; D051381:Rats; D017207:Rats, Sprague-Dawley; D011994:Recombinant Proteins / Q000378:metabolism; D014157:Transcription Factors
C091732:BCL2-associated athanogene 1 protein; D002352:Carrier Proteins; D017931:DNA Primers; D004268:DNA-Binding Proteins; D009097:Multienzyme Complexes; D011994:Recombinant Proteins; D014157:Transcription Factors; D003546:Cysteine Endopeptidases; D046988:Proteasome Endopeptidase Complex