High expression of activation-induced cytidine deaminase (AID) mRNA is associated with unmutated IGVH gene status and unfavourable cytogenetic aberrations in patients with chronic lymphocytic leukaemia.
D015415:Biomarkers / Q000032:analysis; D002869:Chromosome Aberrations; D003564:Cytidine Deaminase / Q000096:biosynthesis / Q000235:genetics*; D018450:Disease Progression; D005260:Female; D006801:Humans; D007135:Immunoglobulin Variable Region / Q000235:genetics*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D016133:Polymerase Chain Reaction / Q000379:methods; D011379:Prognosis; D012333:RNA, Messenger / Q000032:analysis / Q000096:biosynthesis; D012334:RNA, Neoplasm / Q000032:analysis*; D027041:Somatic Hypermutation, Immunoglobulin; D000098830:AICDA (Activation-Induced Cytidine Deaminase)
D015415:Biomarkers; D007135:Immunoglobulin Variable Region; D012333:RNA, Messenger; D012334:RNA, Neoplasm; D000098830:AICDA (Activation-Induced Cytidine Deaminase); D003564:Cytidine Deaminase