Influence of colon degradation of polysaccharide on the oral bioavailability of theophylline from controlled release hydrophilic matrices.
D000328:Adult; D001993:Bronchodilator Agents / Q000008:administration & dosage / Q000493:pharmacokinetics*; D003106:Colon / Q000378:metabolism* / Q000382:microbiology; D003692:Delayed-Action Preparations; D005753:Gastric Mucosa / Q000378:metabolism; D006801:Humans; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000378:metabolism; D011134:Polysaccharides / Q000378:metabolism* / Q000494:pharmacology*; D012995:Solubility; D013806:Theophylline / Q000008:administration & dosage / Q000493:pharmacokinetics*
D001993:Bronchodilator Agents; D003692:Delayed-Action Preparations; D011134:Polysaccharides; D013806:Theophylline