The primary ligand-binding interaction at the GLP-1 receptor is via the putative helix of the peptide agonists.
D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D002460:Cell Line; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D000077270:Exenatide; D005934:Glucagon / Q000737:chemistry* / Q000494:pharmacology*; D052216:Glucagon-Like Peptide 1; D000067757:Glucagon-Like Peptide-1 Receptor; D006801:Humans; D020128:Inhibitory Concentration 50; D008024:Ligands; D008954:Models, Biological; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000737:chemistry* / Q000494:pharmacology*; D010455:Peptides / Q000737:chemistry* / Q000494:pharmacology*; D011498:Protein Precursors / Q000737:chemistry* / Q000494:pharmacology*; D051381:Rats; D018027:Receptors, Glucagon / Q000819:agonists* / Q000737:chemistry* / Q000378:metabolism; D014688:Venoms / Q000737:chemistry* / Q000494:pharmacology*
C000593833:GLP1R protein, human; C000593835:Glp1r protein, rat; D000067757:Glucagon-Like Peptide-1 Receptor; D008024:Ligands; D010446:Peptide Fragments; D010455:Peptides; D011498:Protein Precursors; D018027:Receptors, Glucagon; D014688:Venoms; D052216:Glucagon-Like Peptide 1; D005934:Glucagon; D000077270:Exenatide