The CD20 calcium channel is localized to microvilli and constitutively associated with membrane rafts: antibody binding increases the affinity of the association through an epitope-dependent cross-linking-independent mechanism.
D000199:Actins / Q000737:chemistry; D000255:Adenosine Triphosphate / Q000737:chemistry; D018951:Antigens, CD20 / Q000378:metabolism*; D018957:CD59 Antigens / Q000096:biosynthesis; D045744:Cell Line, Tumor; D002462:Cell Membrane / Q000378:metabolism; D003432:Cross-Linking Reagents / Q000494:pharmacology; D015638:Cytochalasin D / Q000494:pharmacology; D003902:Detergents / Q000494:pharmacology; D000939:Epitopes / Q000737:chemistry; D005434:Flow Cytometry; D006801:Humans; D021962:Membrane Microdomains / Q000378:metabolism*; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence; D008871:Microvilli / Q000378:metabolism*; D008956:Models, Chemical; D017830:Octoxynol / Q000494:pharmacology; D011487:Protein Conformation; D013997:Time Factors; D014162:Transfection
D000199:Actins; D018951:Antigens, CD20; D018957:CD59 Antigens; D003432:Cross-Linking Reagents; D003902:Detergents; D000939:Epitopes; D015638:Cytochalasin D; D000255:Adenosine Triphosphate; D017830:Octoxynol