A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor.
D000803:Angiotensin I / Q000037:antagonists & inhibitors; D000804:Angiotensin II / Q000037:antagonists & inhibitors; D000818:Animals; D001667:Binding, Competitive; D001681:Biological Assay; D002465:Cell Movement / Q000187:drug effects*; D002478:Cells, Cultured; D002642:Chick Embryo; D016384:Consensus Sequence; D042783:Endothelial Cells / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D020929:Mitogen-Activated Protein Kinase Kinases / Q000378:metabolism; D018919:Neovascularization, Physiologic / Q000187:drug effects*; D009842:Oligopeptides / Q000737:chemistry / Q000494:pharmacology*; D019151:Peptide Library; D042787:Receptor, TIE-2 / Q000037:antagonists & inhibitors*; D015398:Signal Transduction / Q000187:drug effects*; D014471:Umbilical Veins / Q000166:cytology; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism
D004791:Enzyme Inhibitors; D009842:Oligopeptides; D019151:Peptide Library; D042461:Vascular Endothelial Growth Factor A; C493332:norleucyl-leucyl-leucyl-methionyl-alanyl-alanyl-serine; D000804:Angiotensin II; D000803:Angiotensin I; D042787:Receptor, TIE-2; D020929:Mitogen-Activated Protein Kinase Kinases