Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia.
D000818:Animals; D001692:Biological Transport; D002460:Cell Line; D002462:Cell Membrane / Q000502:physiology; D003001:Cloning, Molecular; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology / Q000235:genetics*; D007473:Ion Channels / Q000235:genetics* / Q000502:physiology; D007700:Kinetics; D008275:Magnesium Deficiency / Q000235:genetics*; D008345:Manganese / Q000378:metabolism; D008564:Membrane Potentials / Q000502:physiology; D008565:Membrane Proteins / Q000235:genetics* / Q000502:physiology; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics*; D009865:Oocytes / Q000502:physiology; D011494:Protein Kinases / Q000235:genetics* / Q000502:physiology; D017346:Protein Serine-Threonine Kinases; D011994:Recombinant Proteins / Q000378:metabolism; D050053:TRPM Cation Channels; D014982:Xenopus laevis
D007473:Ion Channels; D008565:Membrane Proteins; D011994:Recombinant Proteins; D050053:TRPM Cation Channels; C459082:TRPM6 protein, human; D008345:Manganese; D011494:Protein Kinases; D017346:Protein Serine-Threonine Kinases; C486583:TRPM7 protein, human