title: Pharmacokinetic/pharmacodynamic modeling can help guide targeted antimicrobial therapy for nosocomial gram-negative infections in critically ill patients.
mesh_terms: D018806:APACHE; D000890:Anti-Infective Agents / Q000493:pharmacokinetics / Q000494:pharmacology*; D016638:Critical Illness / Q000628:therapy*; D003428:Cross Infection / Q000188:drug therapy / Q000378:metabolism; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy* / Q000378:metabolism*; D006801:Humans; D008954:Models, Biological; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000378:metabolism; D011550:Pseudomonas aeruginosa / Q000254:growth & development*
chemical_list: D000890:Anti-Infective Agents