IL-12 inhibits thymic involution by enhancing IL-7- and IL-2-induced thymocyte proliferation.
D000276:Adjuvants, Immunologic / Q000096:biosynthesis / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D000375:Aging / Q000235:genetics / Q000276:immunology; D000818:Animals; D017209:Apoptosis / Q000235:genetics / Q000276:immunology; D002455:Cell Division / Q000276:immunology; D002478:Cells, Cultured; D004357:Drug Synergism; D005260:Female; D018664:Interleukin-12 / Q000096:biosynthesis / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D053762:Interleukin-12 Subunit p40; D007376:Interleukin-2 / Q000494:pharmacology*; D015851:Interleukin-7 / Q000494:pharmacology*; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D021122:Protein Subunits / Q000172:deficiency / Q000235:genetics / Q000502:physiology; D015398:Signal Transduction / Q000235:genetics / Q000276:immunology; D016176:T-Lymphocyte Subsets / Q000166:cytology* / Q000276:immunology* / Q000473:pathology; D013950:Thymus Gland / Q000166:cytology / Q000276:immunology* / Q000473:pathology*
D000276:Adjuvants, Immunologic; D053762:Interleukin-12 Subunit p40; D007376:Interleukin-2; D015851:Interleukin-7; D021122:Protein Subunits; D018664:Interleukin-12