Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands.
D000409:Alanine / Q000737:chemistry; D000595:Amino Acid Sequence; D000818:Animals; D001426:Bacterial Proteins; D001665:Binding Sites; D018360:Crystallography, X-Ray; D003523:Cycloserine / Q000737:chemistry; D019992:Databases as Topic; D004926:Escherichia coli / Q000378:metabolism; D018691:Excitatory Amino Acid Antagonists / Q000737:chemistry / Q000494:pharmacology; D005998:Glycine / Q000737:chemistry; D006801:Humans; D006860:Hydrogen Bonding; D007211:Indoles / Q000737:chemistry; D007736:Kynurenic Acid / Q000031:analogs & derivatives* / Q000737:chemistry; D008024:Ligands; D051379:Mice; D008956:Models, Chemical; D008958:Models, Molecular; D008969:Molecular Sequence Data; D015221:Potassium Channels / Q000737:chemistry; D011392:Proline / Q000737:chemistry; D011485:Protein Binding; D011487:Protein Conformation; D020033:Protein Isoforms; D017434:Protein Structure, Tertiary; D051381:Rats; D018091:Receptors, AMPA / Q000737:chemistry; D017470:Receptors, Glutamate / Q000737:chemistry; D016194:Receptors, N-Methyl-D-Aspartate / Q000819:agonists* / Q000037:antagonists & inhibitors* / Q000737:chemistry*; D017386:Sequence Homology, Amino Acid; D012694:Serine / Q000737:chemistry; D013912:Threonine / Q000737:chemistry; D014364:Tryptophan / Q000737:chemistry; D014867:Water / Q000737:chemistry
D001426:Bacterial Proteins; D018691:Excitatory Amino Acid Antagonists; D007211:Indoles; D008024:Ligands; C101788:MDL 105519; D015221:Potassium Channels; D020033:Protein Isoforms; D018091:Receptors, AMPA; D017470:Receptors, Glutamate; D016194:Receptors, N-Methyl-D-Aspartate; C115953:glutamate receptor type B; D014867:Water; D013912:Threonine; D012694:Serine; D014364:Tryptophan; D003523:Cycloserine; D011392:Proline; D007736:Kynurenic Acid; D000409:Alanine; C066192:5,7-dichlorokynurenic acid; D005998:Glycine