Arsenite induces p70S6K1 activation and HIF-1alpha expression in prostate cancer cells.
D018053:Arsenites / Q000494:pharmacology*; D051784:Aryl Hydrocarbon Receptor Nuclear Translocator; D045744:Cell Line, Tumor; D004268:DNA-Binding Proteins; D004789:Enzyme Activation / Q000187:drug effects; D006801:Humans; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D008297:Male; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D010766:Phosphorylation / Q000187:drug effects; D011471:Prostatic Neoplasms / Q000378:metabolism; D011494:Protein Kinases / Q000378:metabolism; D018336:Receptors, Aryl Hydrocarbon / Q000096:biosynthesis*; D038762:Ribosomal Protein S6 Kinases, 70-kDa / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects*; D020123:Sirolimus / Q000494:pharmacology; D058570:TOR Serine-Threonine Kinases; D013723:Teratogens / Q000494:pharmacology*; D014157:Transcription Factors / Q000096:biosynthesis*
D018053:Arsenites; D051784:Aryl Hydrocarbon Receptor Nuclear Translocator; D004268:DNA-Binding Proteins; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D019869:Phosphatidylinositol 3-Kinases; D011494:Protein Kinases; D018336:Receptors, Aryl Hydrocarbon; D038762:Ribosomal Protein S6 Kinases, 70-kDa; D020123:Sirolimus; D058570:TOR Serine-Threonine Kinases; D013723:Teratogens; D014157:Transcription Factors; C497396:ARNT protein, human; C497442:HIF1A protein, human; C546842:MTOR protein, human; C448959:ribosomal protein S6 kinase, 70kD, polypeptide 2; C015001:arsenite