The centromeric region of chromosome 7 from MRL mice (Lmb3) is an epistatic modifier of Fas for autoimmune disease expression.
D000818:Animals; D001323:Autoantibodies / Q000096:biosynthesis; D002503:Centromere / Q000276:immunology*; D004843:Epistasis, Genetic; D005260:Female; D005819:Genetic Markers / Q000276:immunology*; D020022:Genetic Predisposition to Disease; D016130:Immunophenotyping; D008180:Lupus Erythematosus, Systemic / Q000235:genetics* / Q000276:immunology* / Q000473:pathology; D008181:Lupus Nephritis / Q000235:genetics / Q000276:immunology / Q000473:pathology; D016131:Lymphocyte Subsets / Q000473:pathology; D008297:Male; D051379:Mice; D020297:Mice, Congenic; D008810:Mice, Inbred C57BL; D019463:Mice, Inbred MRL lpr; D010641:Phenotype; D019014:fas Receptor / Q000235:genetics*
D001323:Autoantibodies; D005819:Genetic Markers; D019014:fas Receptor