IVIg-mediated amelioration of murine ITP via FcgammaRIIb is not necessarily independent of SHIP-1 and SHP-1 activity.
D020816:Amino Acid Motifs; D000818:Animals; D015703:Antigens, CD / Q000502:physiology*; D007136:Immunoglobulins / Q000627:therapeutic use*; D007262:Infusions, Intravenous; D000072181:Inositol Polyphosphate 5-Phosphatases; D047908:Intracellular Signaling Peptides and Proteins; D051379:Mice; D000072183:Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; D010744:Phosphoric Monoester Hydrolases / Q000502:physiology; D017434:Protein Structure, Tertiary; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; D053824:Protein Tyrosine Phosphatase, Non-Receptor Type 6; D017027:Protein Tyrosine Phosphatases / Q000502:physiology; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000473:pathology*; D017452:Receptors, IgG / Q000502:physiology*; D015398:Signal Transduction; D014443:Tyrosine / Q000737:chemistry
D015703:Antigens, CD; C080571:Fc gamma receptor IIB; D007136:Immunoglobulins; D047908:Intracellular Signaling Peptides and Proteins; D017452:Receptors, IgG; D014443:Tyrosine; D010744:Phosphoric Monoester Hydrolases; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; D053824:Protein Tyrosine Phosphatase, Non-Receptor Type 6; D017027:Protein Tyrosine Phosphatases; C516725:Ptpn11 protein, mouse; C509248:Ptpn6 protein, mouse; D000072181:Inositol Polyphosphate 5-Phosphatases; C000606433:Inpp5d protein, mouse; D000072183:Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases