A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D019208:Brain-Derived Neurotrophic Factor / Q000008:administration & dosage / Q000494:pharmacology*; D003042:Cocaine / Q000009:adverse effects*; D019970:Cocaine-Related Disorders / Q000503:physiopathology*; D003216:Conditioning, Operant / Q000187:drug effects; D003463:Cues; D004195:Disease Models, Animal; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005108:Extinction, Psychological / Q000187:drug effects; D007263:Infusions, Parenteral; D008297:Male; D020932:Nerve Growth Factor / Q000008:administration & dosage / Q000494:pharmacology; D051381:Rats; D020318:Rats, Long-Evans; D013375:Substance Withdrawal Syndrome / Q000503:physiopathology*; D013378:Substantia Nigra / Q000187:drug effects; D013997:Time Factors; D017557:Ventral Tegmental Area / Q000187:drug effects* / Q000503:physiopathology
D019208:Brain-Derived Neurotrophic Factor; D004791:Enzyme Inhibitors; D020932:Nerve Growth Factor; D003042:Cocaine