Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors.
D000818:Animals; D004625:Embryo, Nonmammalian / Q000502:physiology; D018507:Gene Expression Regulation, Developmental; D036341:Intercellular Signaling Peptides and Proteins / Q000235:genetics*; D008969:Molecular Sequence Data; D018125:Receptors, Transforming Growth Factor beta / Q000235:genetics*; D016212:Transforming Growth Factor beta / Q000235:genetics*; D014981:Xenopus / Q000196:embryology; D029867:Xenopus Proteins / Q000235:genetics
C491268:CFC1 protein, human; D036341:Intercellular Signaling Peptides and Proteins; D018125:Receptors, Transforming Growth Factor beta; D016212:Transforming Growth Factor beta; D029867:Xenopus Proteins