Differentiated thyroid carcinomas from children and adolescents express IGF-I and the IGF-I receptor (IGF-I-R). Cancers with the most intense IGF-I-R expression may be more aggressive.
D018263:Adenocarcinoma, Follicular / Q000378:metabolism / Q000473:pathology; D000293:Adolescent; D000328:Adult; D002291:Carcinoma, Papillary / Q000378:metabolism / Q000473:pathology; D002648:Child; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D008297:Male; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D017526:Receptor, IGF Type 1 / Q000378:metabolism*; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology*
D007334:Insulin-Like Growth Factor I; D017526:Receptor, IGF Type 1