title: Rapid evolution in conformational space: a study of loop regions in a ubiquitous GTP binding domain.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites / Q000235:genetics; D015852:Eukaryotic Initiation Factor-2 / Q000737:chemistry / Q000235:genetics; D019143:Evolution, Molecular; D019205:GTP-Binding Protein alpha Subunits, Gs / Q000737:chemistry / Q000235:genetics; D019204:GTP-Binding Proteins / Q000737:chemistry* / Q000235:genetics; D017353:Gene Deletion; D006801:Humans; D008957:Models, Genetic; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016254:Mutagenesis, Insertional; D010802:Phylogeny; D011487:Protein Conformation; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry / Q000235:genetics; D016283:Proto-Oncogene Proteins p21(ras) / Q000737:chemistry / Q000235:genetics; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry / Q000235:genetics; D016415:Sequence Alignment; D013269:Stochastic Processes; D040681:Structural Homology, Protein; D020691:rab GTP-Binding Proteins / Q000737:chemistry / Q000235:genetics
chemical_list: D015852:Eukaryotic Initiation Factor-2; C490287:GBP1 protein, human; D011506:Proteins; D029701:Saccharomyces cerevisiae Proteins; D019204:GTP-Binding Proteins; C086866:VPS21 protein, S cerevisiae; D019205:GTP-Binding Protein alpha Subunits, Gs; C501009:HRAS protein, human; D016283:Proto-Oncogene Proteins p21(ras); D020691:rab GTP-Binding Proteins