Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes.
D000103:Acetyl-CoA Carboxylase / Q000378:metabolism; D002001:Adipose Tissue, Brown / Q000187:drug effects / Q000503:physiopathology; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D003920:Diabetes Mellitus / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology*; D004032:Diet; D005346:Fibroblast Growth Factors / Q000494:pharmacology*; D015870:Gene Expression / Q000187:drug effects; D006801:Humans; D020738:Leptin / Q000172:deficiency*; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008660:Metabolism / Q000187:drug effects; D051379:Mice; D008822:Mice, Transgenic; D009765:Obesity; D011956:Receptors, Cell Surface / Q000378:metabolism; D054411:Receptors, Leptin; D011994:Recombinant Proteins / Q000494:pharmacology*
C117476:FGF19 protein, human; C515448:LEPR protein, human; D020738:Leptin; D011956:Receptors, Cell Surface; D054411:Receptors, Leptin; D011994:Recombinant Proteins; C515447:leptin receptor, mouse; D005346:Fibroblast Growth Factors; D000103:Acetyl-CoA Carboxylase