Suramin has adjuvant properties and promotes expansion of antigen-specific Th1 and Th2 cells in vivo.
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000536:Aluminum Hydroxide / Q000494:pharmacology; D000818:Animals; D005260:Female; D005620:Freund's Adjuvant / Q000494:pharmacology; D019204:GTP-Binding Proteins / Q000819:agonists / Q000037:antagonists & inhibitors*; D006084:Graft Rejection / Q000276:immunology; D007114:Immunization; D066298:In Vitro Techniques; D018664:Interleukin-12 / Q000378:metabolism; D015850:Interleukin-6 / Q000378:metabolism; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009113:Muramidase / Q000276:immunology; D058919:Purinergic P2 Receptor Antagonists; D016038:Skin Transplantation / Q000276:immunology; D013498:Suramin / Q000494:pharmacology*; D018417:Th1 Cells / Q000166:cytology / Q000187:drug effects* / Q000276:immunology; D018418:Th2 Cells / Q000166:cytology / Q000187:drug effects* / Q000276:immunology
D000276:Adjuvants, Immunologic; D015850:Interleukin-6; D058919:Purinergic P2 Receptor Antagonists; D018664:Interleukin-12; D000536:Aluminum Hydroxide; D013498:Suramin; D005620:Freund's Adjuvant; C421864:hen egg lysozyme; D009113:Muramidase; D019204:GTP-Binding Proteins