Integrins regulate survival of pre-B-ALL cells through differential IAP and caspase-7 ubiquitination and degradation.
D017209:Apoptosis; D053179:Caspase 7; D020169:Caspases / Q000032:analysis / Q000378:metabolism*; D002470:Cell Survival; D006801:Humans; D051034:Inhibitor of Apoptosis Proteins; D016023:Integrins / Q000502:physiology*; D007700:Kinetics; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology*; D011506:Proteins / Q000032:analysis / Q000378:metabolism*; D025801:Ubiquitin / Q000378:metabolism; D051636:X-Linked Inhibitor of Apoptosis Protein
D051034:Inhibitor of Apoptosis Proteins; D016023:Integrins; D011506:Proteins; D025801:Ubiquitin; D051636:X-Linked Inhibitor of Apoptosis Protein; C496866:XIAP protein, human; C505520:CASP7 protein, human; D053179:Caspase 7; D020169:Caspases