Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells.
D000818:Animals; D000963:Antimetabolites / Q000494:pharmacology; D001854:Bone Marrow Cells / Q000166:cytology / Q000187:drug effects / Q000502:physiology; D002452:Cell Count; D002455:Cell Division / Q000502:physiology; D005260:Female; D016332:Fetal Tissue Transplantation; D005472:Fluorouracil / Q000494:pharmacology; D018507:Gene Expression Regulation, Developmental; D006410:Hematopoiesis / Q000502:physiology*; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000187:drug effects / Q000502:physiology*; D022781:Hepatocytes / Q000166:cytology / Q000637:transplantation; D018398:Homeodomain Proteins / Q000235:genetics*; D008099:Liver / Q000166:cytology / Q000196:embryology / Q000502:physiology; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D023421:Models, Animal; D011247:Pregnancy; D014157:Transcription Factors / Q000235:genetics*
D000963:Antimetabolites; D018398:Homeodomain Proteins; C513262:Hoxb4 protein, mouse; D014157:Transcription Factors; D005472:Fluorouracil