Diallyl disulfide (DADS) increases histone acetylation and p21(waf1/cip1) expression in human colon tumor cell lines.
D000107:Acetylation / Q000187:drug effects; D000498:Allyl Compounds / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000494:pharmacology*; D018938:Caco-2 Cells; D003110:Colonic Neoplasms / Q000188:drug therapy*; D050759:Cyclin-Dependent Kinase Inhibitor p21; D016213:Cyclins / Q000096:biosynthesis / Q000187:drug effects* / Q000235:genetics; D004220:Disulfides / Q000494:pharmacology*; D016195:G2 Phase / Q000187:drug effects; D006367:HeLa Cells; D006657:Histones / Q000187:drug effects*; D006801:Humans; D012333:RNA, Messenger / Q000187:drug effects / Q000378:metabolism
D000498:Allyl Compounds; D000970:Antineoplastic Agents; C493956:CDKN1A protein, human; D050759:Cyclin-Dependent Kinase Inhibitor p21; D016213:Cyclins; D004220:Disulfides; D006657:Histones; D012333:RNA, Messenger; C028009:diallyl disulfide