Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair.
D000818:Animals; D020137:Base Pair Mismatch; D001665:Binding Sites; D001921:Brain / Q000378:metabolism; D019951:DNA Polymerase beta / Q000378:metabolism*; D004260:DNA Repair; D043603:DNA-(Apurinic or Apyrimidinic Site) Lyase / Q000172:deficiency* / Q000235:genetics; D006239:Haplotypes; D006579:Heterozygote; D008099:Liver / Q000378:metabolism; D008297:Male; D051379:Mice; D018345:Mice, Knockout; D009928:Organ Specificity; D010084:Oxidation-Reduction; D013737:Testis / Q000378:metabolism
D019951:DNA Polymerase beta; C486216:Apex1 protein, mouse; D043603:DNA-(Apurinic or Apyrimidinic Site) Lyase