Efforts to understand the molecular basis of hypertension through drug:membrane interactions.
D000596:Amino Acids / Q000737:chemistry / Q000378:metabolism; D047228:Angiotensin II Type 1 Receptor Blockers; D000959:Antihypertensive Agents / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D001665:Binding Sites; D001713:Biphenyl Compounds / Q000737:chemistry / Q000494:pharmacology; D002152:Calorimetry, Differential Scanning; D002462:Cell Membrane / Q000737:chemistry / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology; D007093:Imidazoles / Q000737:chemistry / Q000494:pharmacology; D000077405:Irbesartan; D019808:Losartan / Q000737:chemistry / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D044140:Receptor, Angiotensin, Type 1 / Q000737:chemistry; D013777:Tetrazoles / Q000737:chemistry / Q000494:pharmacology; D014961:X-Ray Diffraction
D000596:Amino Acids; D047228:Angiotensin II Type 1 Receptor Blockers; D000959:Antihypertensive Agents; D001713:Biphenyl Compounds; D007093:Imidazoles; D044140:Receptor, Angiotensin, Type 1; D013777:Tetrazoles; C066026:losartan carboxylic acid; D000077405:Irbesartan; D019808:Losartan