Human models of inherited immunoglobulin class switch recombination and somatic hypermutation defects (hyper-IgM syndromes).
D000917:Antibody Formation; D001402:B-Lymphocytes / Q000276:immunology*; D019013:CD40 Antigens / Q000276:immunology; D023201:CD40 Ligand / Q000276:immunology; D006801:Humans; D017578:Immunoglobulin Class Switching; D007134:Immunoglobulin Switch Region; D008213:Lymphocyte Activation / Q000276:immunology; D018448:Models, Immunological; D027041:Somatic Hypermutation, Immunoglobulin
D019013:CD40 Antigens; D023201:CD40 Ligand