Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia).
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D000924:Anticholesteremic Agents / Q000378:metabolism* / Q000493:pharmacokinetics; D001384:Azetidines / Q000378:metabolism* / Q000493:pharmacokinetics; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid; D018076:DNA, Complementary / Q000378:metabolism; D004008:Diclofenac / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000494:pharmacology; D000069438:Ezetimibe; D020719:Glucuronides / Q000378:metabolism; D014453:Glucuronosyltransferase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006801:Humans; D006868:Hydrolysis; D066298:In Vitro Techniques; D007527:Isoenzymes / Q000378:metabolism; D007583:Jejunum / Q000201:enzymology; D013058:Mass Spectrometry; D008861:Microsomes / Q000201:enzymology; D008862:Microsomes, Liver / Q000201:enzymology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000924:Anticholesteremic Agents; D001384:Azetidines; D018076:DNA, Complementary; D004791:Enzyme Inhibitors; D020719:Glucuronides; D007527:Isoenzymes; D004008:Diclofenac; D014453:Glucuronosyltransferase; D000069438:Ezetimibe