Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3.
D000818:Animals; D001035:Aphakia / Q000196:embryology / Q000235:genetics; D001522:Behavior, Animal; D004298:Dopamine / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental; D005801:Genes, Homeobox; D018398:Homeodomain Proteins / Q000235:genetics*; D017403:In Situ Hybridization; D008636:Mesencephalon / Q000196:embryology; D051379:Mice; D008810:Mice, Inbred C57BL; D008817:Mice, Mutant Strains; D009474:Neurons / Q000166:cytology / Q000378:metabolism; D016548:Prosencephalon / Q000196:embryology; D013378:Substantia Nigra / Q000196:embryology*; D014157:Transcription Factors / Q000172:deficiency* / Q000235:genetics*
D018398:Homeodomain Proteins; D014157:Transcription Factors; C433629:homeobox protein PITX3; D004298:Dopamine