Divergent consequences arise from metallothionein overexpression in astrocytes: zinc buffering and oxidant-induced zinc release.
D000818:Animals; D001253:Astrocytes / Q000187:drug effects* / Q000378:metabolism*; D015687:Cell Hypoxia / Q000187:drug effects / Q000502:physiology; D002478:Cells, Cultured; D005786:Gene Expression Regulation / Q000502:physiology; D008668:Metallothionein / Q000096:biosynthesis* / Q000235:genetics / Q000494:pharmacology; D016877:Oxidants / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D015032:Zinc / Q000378:metabolism*
D016877:Oxidants; D008668:Metallothionein; D015032:Zinc