Transcription factor tonicity-responsive enhancer-binding protein (TonEBP) which transactivates osmoprotective genes is expressed and upregulated following acute systemic hypertonicity in neurons in brain.
D000818:Animals; D002540:Cerebral Cortex / Q000166:cytology / Q000502:physiology*; D004326:Drinking / Q000502:physiology; D015870:Gene Expression / Q000502:physiology; D006624:Hippocampus / Q000166:cytology / Q000502:physiology*; D006955:Hypernatremia / Q000503:physiopathology; D006982:Hypertonic Solutions / Q000494:pharmacology; D007150:Immunohistochemistry; D008297:Male; D009474:Neurons / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013395:Sucrose / Q000494:pharmacology; D015534:Trans-Activators / Q000378:metabolism*; D014157:Transcription Factors; D014868:Water Deprivation / Q000502:physiology; D014869:Water Intoxication / Q000503:physiopathology; D014882:Water-Electrolyte Balance / Q000502:physiology*
D006982:Hypertonic Solutions; C492199:Nfat5 protein, rat; D015534:Trans-Activators; D014157:Transcription Factors; D013395:Sucrose