Tumor growth suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via lipid peroxidation.
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology; D017209:Apoptosis; D053148:Caspase 3; D020169:Caspases / Q000378:metabolism; D002455:Cell Division; D002849:Chromatography, Gas; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000473:pathology; D004247:DNA / Q000737:chemistry; D053938:DNA Fragmentation; D004305:Dose-Response Relationship, Drug; D005227:Fatty Acids / Q000378:metabolism; D006801:Humans; D006861:Hydrogen Peroxide / Q000737:chemistry; D008042:Linolenic Acids / Q000494:pharmacology*; D015227:Lipid Peroxidation; D008297:Male; D051379:Mice; D008819:Mice, Nude; D008956:Models, Chemical; D009368:Neoplasm Transplantation; D018384:Oxidative Stress; D010743:Phospholipids / Q000378:metabolism; D012313:RNA / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017392:Thiobarbituric Acid Reactive Substances; D017962:alpha-Linolenic Acid / Q000737:chemistry*; D024502:alpha-Tocopherol / Q000378:metabolism
D000970:Antineoplastic Agents; D000975:Antioxidants; D005227:Fatty Acids; D008042:Linolenic Acids; D010743:Phospholipids; D012333:RNA, Messenger; D017392:Thiobarbituric Acid Reactive Substances; D017962:alpha-Linolenic Acid; C004934:eleostearic acid; D012313:RNA; D004247:DNA; D006861:Hydrogen Peroxide; C505407:CASP3 protein, human; C505409:Casp3 protein, mouse; D053148:Caspase 3; D020169:Caspases; D024502:alpha-Tocopherol