Oligonucleotides blocking glucosylceramide synthase expression selectively reverse drug resistance in cancer cells.
D017209:Apoptosis / Q000187:drug effects; D001943:Breast Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000473:pathology; D045744:Cell Line, Tumor; D019008:Drug Resistance, Neoplasm / Q000187:drug effects*; D005786:Gene Expression Regulation / Q000187:drug effects*; D005964:Glucosyltransferases / Q000096:biosynthesis* / Q000235:genetics*; D006801:Humans; D020319:Oligodeoxyribonucleotides, Antisense / Q000235:genetics / Q000378:metabolism / Q000494:pharmacology*; D020112:Rhodamine 123 / Q000378:metabolism; D013379:Substrate Specificity
D020319:Oligodeoxyribonucleotides, Antisense; D020112:Rhodamine 123; D005964:Glucosyltransferases; C023246:ceramide glucosyltransferase