Barley beta-glucan lowers serum cholesterol based on the up-regulation of cholesterol 7alpha-hydroxylase activity and mRNA abundance in cholesterol-fed rats.
D000818:Animals; D000924:Anticholesteremic Agents / Q000008:administration & dosage / Q000494:pharmacology; D001647:Bile Acids and Salts / Q000378:metabolism; D002784:Cholesterol / Q000097:blood*; D002790:Cholesterol 7-alpha-Hydroxylase / Q000235:genetics* / Q000378:metabolism*; D002791:Cholesterol, Dietary / Q000008:administration & dosage*; D008078:Cholesterol, LDL / Q000097:blood; D004032:Diet; D005243:Feces / Q000737:chemistry; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects; D005936:Glucans / Q000008:administration & dosage / Q000494:pharmacology*; D001467:Hordeum / Q000737:chemistry*; D008099:Liver / Q000201:enzymology; D008297:Male; D012333:RNA, Messenger / Q000032:analysis; D051381:Rats; D017207:Rats, Sprague-Dawley
D000924:Anticholesteremic Agents; D001647:Bile Acids and Salts; D002791:Cholesterol, Dietary; D008078:Cholesterol, LDL; D005936:Glucans; D012333:RNA, Messenger; D002784:Cholesterol; D002790:Cholesterol 7-alpha-Hydroxylase