Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation.
D000818:Animals; D000942:Antigens, Bacterial / Q000378:metabolism / Q000502:physiology*; D001426:Bacterial Proteins / Q000378:metabolism / Q000502:physiology*; D019556:COS Cells; D002460:Cell Line; D018076:DNA, Complementary / Q000378:metabolism; D004789:Enzyme Activation; D005822:Genetic Vectors; D016480:Helicobacter pylori / Q000378:metabolism*; D006801:Humans; D015151:Immunoblotting; D047908:Intracellular Signaling Peptides and Proteins; D018715:Microscopy, Video; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism; D010641:Phenotype; D010766:Phosphorylation; D011233:Precipitin Tests; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; D017027:Protein Tyrosine Phosphatases / Q000378:metabolism*; D034622:RNA Interference; D034741:RNA, Small Interfering / Q000378:metabolism; D054593:SH2 Domain-Containing Protein Tyrosine Phosphatases; D013270:Stomach / Q000382:microbiology / Q000473:pathology; D013997:Time Factors; D014162:Transfection; D014443:Tyrosine / Q000737:chemistry / Q000378:metabolism; D018631:ras Proteins / Q000378:metabolism
D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D018076:DNA, Complementary; D047908:Intracellular Signaling Peptides and Proteins; D034741:RNA, Small Interfering; C080866:cagA protein, Helicobacter pylori; D014443:Tyrosine; D020928:Mitogen-Activated Protein Kinases; C516724:PTPN11 protein, human; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; D017027:Protein Tyrosine Phosphatases; D054593:SH2 Domain-Containing Protein Tyrosine Phosphatases; D018631:ras Proteins