Carbachol regulation of rabbit ileal brush border Na+-H+ exchanger 3 (NHE3) occurs through changes in NHE3 trafficking and complex formation and is Src dependent.
D000185:Actinin / Q000378:metabolism*; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D015153:Blotting, Western; D000081247:CSK Tyrosine-Protein Kinase; D002217:Carbachol / Q000494:pharmacology*; D011992:Endosomes / Q000737:chemistry; D004847:Epithelial Cells / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D007082:Ileum / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D047468:Immunoprecipitation; D008297:Male; D008856:Microscopy, Fluorescence; D008871:Microvilli / Q000187:drug effects / Q000378:metabolism; D010766:Phosphorylation; D011485:Protein Binding / Q000187:drug effects; D021381:Protein Transport / Q000187:drug effects; D011505:Protein-Tyrosine Kinases / Q000032:analysis / Q000378:metabolism; D011743:Pyrimidines / Q000494:pharmacology; D011817:Rabbits; D000074083:Sodium-Hydrogen Exchanger 3; D017923:Sodium-Hydrogen Exchangers / Q000378:metabolism / Q000502:physiology*; D014867:Water / Q000032:analysis / Q000378:metabolism; D019061:src-Family Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000502:physiology*
C412373:AG 1879; D011743:Pyrimidines; D000074083:Sodium-Hydrogen Exchanger 3; D017923:Sodium-Hydrogen Exchangers; D014867:Water; D000185:Actinin; D002217:Carbachol; D011505:Protein-Tyrosine Kinases; D000081247:CSK Tyrosine-Protein Kinase; D019061:src-Family Kinases