A new hypotensive polyunsaturated fatty acid dietary combination regulates oleic acid accumulation by suppression of stearoyl CoA desaturase 1 gene expression in the SHR model of genetic hypertension.
D000284:Administration, Oral; D000818:Animals; D001794:Blood Pressure; D005227:Fatty Acids / Q000032:analysis; D005231:Fatty Acids, Unsaturated / Q000008:administration & dosage / Q000032:analysis / Q000494:pharmacology*; D015971:Gene Expression Regulation, Enzymologic; D022781:Hepatocytes / Q000378:metabolism; D006973:Hypertension / Q000201:enzymology / Q000235:genetics / Q000378:metabolism*; D008055:Lipids / Q000737:chemistry; D008954:Models, Biological; D019301:Oleic Acid / Q000378:metabolism*; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY; D013230:Stearoyl-CoA Desaturase / Q000235:genetics / Q000378:metabolism*; D014280:Triglycerides / Q000097:blood / Q000737:chemistry
D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; D008055:Lipids; D014280:Triglycerides; D019301:Oleic Acid; D013230:Stearoyl-CoA Desaturase