Intracellular expression of engineered RNase P ribozymes effectively blocks gene expression and replication of human cytomegalovirus.
D003587:Cytomegalovirus / Q000201:enzymology / Q000235:genetics* / Q000378:metabolism; D010450:Endopeptidases / Q000096:biosynthesis / Q000235:genetics; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics; D015967:Gene Expression Regulation, Viral; D005818:Genetic Engineering; D006801:Humans; D016337:RNA, Catalytic / Q000235:genetics* / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism; D043262:Ribonuclease P / Q000235:genetics* / Q000378:metabolism; D014764:Viral Proteins / Q000096:biosynthesis / Q000235:genetics
D016337:RNA, Catalytic; D012333:RNA, Messenger; D014764:Viral Proteins; C058313:assembly protein, Cytomegalovirus; D043262:Ribonuclease P; D010450:Endopeptidases