title: Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression.
mesh_terms: D001189:Aryl Hydrocarbon Hydroxylases / Q000096:biosynthesis / Q000235:genetics; D018938:Caco-2 Cells; D002460:Cell Line; D003001:Cloning, Molecular; D051544:Cytochrome P-450 CYP3A; D017931:DNA Primers; D004347:Drug Interactions; D004790:Enzyme Induction / Q000187:drug effects; D015971:Gene Expression Regulation, Enzymologic / Q000235:genetics / Q000502:physiology*; D014453:Glucuronosyltransferase / Q000096:biosynthesis* / Q000235:genetics*; D006801:Humans; D007422:Intestines / Q000201:enzymology; D007527:Isoenzymes / Q000096:biosynthesis / Q000235:genetics; D008099:Liver / Q000201:enzymology; D010957:Plasmids / Q000235:genetics; D000077297:Pregnane X Receptor; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics; D018160:Receptors, Cytoplasmic and Nuclear / Q000235:genetics* / Q000378:metabolism*; D011987:Receptors, Steroid / Q000235:genetics* / Q000378:metabolism*; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: D017931:DNA Primers; D007527:Isoenzymes; D000077297:Pregnane X Receptor; D012333:RNA, Messenger; D018160:Receptors, Cytoplasmic and Nuclear; D011987:Receptors, Steroid; D001189:Aryl Hydrocarbon Hydroxylases; C103123:CYP3A7 protein, human; D051544:Cytochrome P-450 CYP3A; D014453:Glucuronosyltransferase