PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress.
D000818:Animals; D017209:Apoptosis; D015152:Blotting, Northern; D015139:Blotting, Southern; D002470:Cell Survival; D002478:Cells, Cultured; D046508:Culture Techniques; D004268:DNA-Binding Proteins / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D005347:Fibroblasts / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D015151:Immunoblotting; D051379:Mice; D008856:Microscopy, Fluorescence; D051267:NF-E2-Related Factor 2; D010084:Oxidation-Reduction; D018384:Oxidative Stress; D010957:Plasmids / Q000378:metabolism; D011233:Precipitin Tests; D017510:Protein Folding; D017382:Reactive Oxygen Species; D015398:Signal Transduction; D013347:Subcellular Fractions; D013997:Time Factors; D015534:Trans-Activators / Q000378:metabolism*; D014162:Transfection; D019892:eIF-2 Kinase / Q000378:metabolism*
D004268:DNA-Binding Proteins; D005947:Glucose; D005978:Glutathione; D051267:NF-E2-Related Factor 2; D017382:Reactive Oxygen Species; D015534:Trans-Activators; D019892:eIF-2 Kinase; C495636:Nfe2l2 protein, mouse