title: Glycosylation-independent targeting enhances enzyme delivery to lysosomes and decreases storage in mucopolysaccharidosis type VII mice.
mesh_terms: D000818:Animals; D016466:CHO Cells; D006224:Cricetinae; D004195:Disease Models, Animal; D057487:Enzyme Therapy; D004798:Enzymes / Q000235:genetics; D015316:Genetic Therapy; D005966:Glucuronidase / Q000235:genetics / Q000627:therapeutic use*; D006801:Humans; D007335:Insulin-Like Growth Factor II / Q000235:genetics*; D008247:Lysosomes / Q000201:enzymology*; D051379:Mice; D016538:Mucopolysaccharidosis VII / Q000188:drug therapy*; D016254:Mutagenesis, Insertional; D011994:Recombinant Proteins / Q000378:metabolism; D014162:Transfection
chemical_list: D004798:Enzymes; D011994:Recombinant Proteins; D007335:Insulin-Like Growth Factor II; D005966:Glucuronidase