Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease.
D000236:Adenoma / Q000378:metabolism / Q000473:pathology; D000483:Alleles; D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology / Q000378:metabolism; D016026:Bone Marrow Transplantation; D002478:Cells, Cultured; D015972:Gene Expression Regulation, Neoplastic; D011905:Genes, ras; D006412:Hematopoietic Stem Cells / Q000378:metabolism; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000378:metabolism; D051379:Mice; D008815:Mice, Inbred Strains; D008822:Mice, Transgenic; D009196:Myeloproliferative Disorders / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D009369:Neoplasms / Q000378:metabolism / Q000473:pathology; D010212:Papilloma / Q000378:metabolism / Q000473:pathology; D010641:Phenotype; D011401:Promoter Regions, Genetic