Decreased immunodensities of micro-opioid receptors, receptor kinases GRK 2/6 and beta-arrestin-2 in postmortem brains of opiate addicts.
D000328:Adult; D019390:Arrestins / Q000378:metabolism*; D016022:Case-Control Studies; D017868:Cyclic AMP-Dependent Protein Kinases / Q000378:metabolism*; D005260:Female; D054768:G-Protein-Coupled Receptor Kinases; D006801:Humans; D015151:Immunoblotting / Q000379:methods; D008297:Male; D008691:Methadone / Q000009:adverse effects; D008875:Middle Aged; D009293:Opioid-Related Disorders / Q000378:metabolism*; D011180:Postmortem Changes; D017397:Prefrontal Cortex / Q000187:drug effects / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D017450:Receptors, Opioid, mu / Q000378:metabolism*; D051552:beta-Adrenergic Receptor Kinases; D000071560:beta-Arrestin 2; D000071557:beta-Arrestins
C000605254:ARRB2 protein, human; D019390:Arrestins; D017450:Receptors, Opioid, mu; D000071560:beta-Arrestin 2; D000071557:beta-Arrestins; D017346:Protein Serine-Threonine Kinases; D017868:Cyclic AMP-Dependent Protein Kinases; D051552:beta-Adrenergic Receptor Kinases; D054768:G-Protein-Coupled Receptor Kinases; C089176:G-protein-coupled receptor kinase 6; D008691:Methadone