The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis.
D000818:Animals; D000843:Ankle Joint / Q000000981:diagnostic imaging / Q000473:pathology; D015703:Antigens, CD / Q000235:genetics*; D001172:Arthritis, Rheumatoid / Q000235:genetics* / Q000276:immunology* / Q000473:pathology; D050822:Cytokine Receptor gp130; D004195:Disease Models, Animal; D005434:Flow Cytometry; D016355:Genes, pX / Q000235:genetics* / Q000276:immunology; D015368:Human T-lymphotropic virus 1 / Q000235:genetics* / Q000276:immunology; D015850:Interleukin-6 / Q000276:immunology; D008198:Lymph Nodes / Q000166:cytology; D008562:Membrane Glycoproteins / Q000235:genetics*; D051379:Mice; D008810:Mice, Inbred C57BL; D022423:Myeloid Cells / Q000276:immunology; D017354:Point Mutation / Q000235:genetics / Q000276:immunology; D011859:Radiography; D013154:Spleen / Q000166:cytology; D016176:T-Lymphocyte Subsets / Q000276:immunology; D014443:Tyrosine / Q000235:genetics
D015703:Antigens, CD; C494200:Il6st protein, mouse; D015850:Interleukin-6; D008562:Membrane Glycoproteins; D050822:Cytokine Receptor gp130; D014443:Tyrosine