Human CD8+ T cells store RANTES in a unique secretory compartment and release it rapidly after TcR stimulation.
D018414:CD8-Positive T-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D002478:Cells, Cultured; D018946:Chemokine CCL5 / Q000378:metabolism*; D003513:Cycloheximide / Q000494:pharmacology; D005434:Flow Cytometry; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects / Q000276:immunology*; D018613:Microscopy, Confocal; D008856:Microscopy, Fluorescence; D016253:Microscopy, Immunoelectron; D011500:Protein Synthesis Inhibitors / Q000494:pharmacology; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D022142:Secretory Vesicles / Q000378:metabolism* / Q000648:ultrastructure
D018946:Chemokine CCL5; D011500:Protein Synthesis Inhibitors; D011948:Receptors, Antigen, T-Cell; D003513:Cycloheximide