title: Function-blocking integrin alphavbeta6 monoclonal antibodies: distinct ligand-mimetic and nonligand-mimetic classes.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000911:Antibodies, Monoclonal / Q000378:metabolism; D000951:Antigens, Neoplasm / Q000737:chemistry* / Q000276:immunology; D001667:Binding, Competitive; D002412:Cations; D002448:Cell Adhesion; D018076:DNA, Complementary / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D000939:Epitopes / Q000737:chemistry; D005353:Fibronectins / Q000737:chemistry / Q000378:metabolism; D005434:Flow Cytometry; D006801:Humans; D007118:Immunoassay; D020128:Inhibitory Concentration 50; D016023:Integrins / Q000737:chemistry* / Q000276:immunology; D007700:Kinetics; D008024:Ligands; D051379:Mice; D008822:Mice, Transgenic; D008969:Molecular Sequence Data; D041681:NIH 3T3 Cells; D009842:Oligopeptides / Q000737:chemistry; D010455:Peptides / Q000737:chemistry; D010974:Platelet Aggregation; D011485:Protein Binding; D011994:Recombinant Proteins / Q000737:chemistry; D017386:Sequence Homology, Amino Acid; D014162:Transfection; D016212:Transforming Growth Factor beta / Q000378:metabolism; D053773:Transforming Growth Factor beta1
chemical_list: D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D002412:Cations; D018076:DNA, Complementary; D000939:Epitopes; D005353:Fibronectins; D016023:Integrins; D008024:Ligands; D009842:Oligopeptides; D010455:Peptides; D011994:Recombinant Proteins; C508960:TGFB1 protein, human; C508961:Tgfb1 protein, mouse; D016212:Transforming Growth Factor beta; D053773:Transforming Growth Factor beta1; C073878:integrin alphavbeta6; C047981:arginyl-glycyl-aspartic acid