The inhibitory role of lactacystin and beta-lactacystin on T-cell activation and proliferation.
D000111:Acetylcysteine / Q000031:analogs & derivatives* / Q000494:pharmacology*; D015703:Antigens, CD / Q000096:biosynthesis; D000945:Antigens, Differentiation, T-Lymphocyte / Q000096:biosynthesis; D017252:CD3 Complex / Q000096:biosynthesis; D002455:Cell Division; D015853:Cysteine Proteinase Inhibitors / Q000494:pharmacology; D015536:Down-Regulation; D005434:Flow Cytometry; D006801:Humans; D007376:Interleukin-2 / Q000378:metabolism; D037181:Lectins, C-Type; D007963:Leukocytes, Mononuclear / Q000378:metabolism; D008213:Lymphocyte Activation; D009124:Muscle Proteins / Q000378:metabolism; D046988:Proteasome Endopeptidase Complex; D011506:Proteins / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism; D015375:Receptors, Interleukin-2 / Q000096:biosynthesis / Q000737:chemistry; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013601:T-Lymphocytes / Q000378:metabolism*; D013997:Time Factors; D000099192:CD69 Antigens
D000111:Acetylcysteine; D015703:Antigens, CD; D000945:Antigens, Differentiation, T-Lymphocyte; D017252:CD3 Complex; D015853:Cysteine Proteinase Inhibitors; D007376:Interleukin-2; D037181:Lectins, C-Type; D009124:Muscle Proteins; D046988:Proteasome Endopeptidase Complex; D011506:Proteins; D012333:RNA, Messenger; D015375:Receptors, Interleukin-2; D000099192:CD69 Antigens; C085047:PSME1 protein, human; C488643:lactacystin beta-lactone; C067713:lactacystin