title: Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease.
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D001370:Axonal Transport; D001369:Axons / Q000502:physiology*; D003593:Cytoplasm / Q000502:physiology; D004195:Disease Models, Animal; D004331:Drosophila melanogaster / Q000254:growth & development / Q000502:physiology*; D004596:Electroretinography; D006801:Humans; D000071058:Huntingtin Protein; D006816:Huntington Disease; D007814:Larva; D018482:Muscle, Skeletal / Q000502:physiology; D009410:Nerve Degeneration / Q000235:genetics; D009419:Nerve Tissue Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D009474:Neurons / Q000166:cytology / Q000473:pathology / Q000502:physiology; D009687:Nuclear Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D010455:Peptides
chemical_list: C086055:HTT protein, human; D000071058:Huntingtin Protein; D009419:Nerve Tissue Proteins; D009687:Nuclear Proteins; D010455:Peptides; C097188:polyglutamine