A polymorphic autoregulatory hormone response element in the human estrogen-related receptor alpha (ERRalpha) promoter dictates peroxisome proliferator-activated receptor gamma coactivator-1alpha control of ERRalpha expression.
D002170:Canada / Q000453:epidemiology; D004252:DNA Mutational Analysis; D025461:Feedback, Physiological / Q000235:genetics*; D005260:Female; D018628:Gene Dosage; D005820:Genetic Testing; D006360:Heat-Shock Proteins / Q000502:physiology*; D006728:Hormones / Q000502:physiology; D006801:Humans; D000071248:Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic / Q000235:genetics*; D018160:Receptors, Cytoplasmic and Nuclear / Q000096:biosynthesis / Q000235:genetics* / Q000378:metabolism; D011960:Receptors, Estrogen / Q000096:biosynthesis / Q000235:genetics* / Q000378:metabolism; D020218:Response Elements / Q000235:genetics*; D014157:Transcription Factors / Q000378:metabolism / Q000502:physiology*; D000097983:ERRalpha Estrogen-Related Receptor
D006360:Heat-Shock Proteins; D006728:Hormones; D000071248:Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; D018160:Receptors, Cytoplasmic and Nuclear; D011960:Receptors, Estrogen; D014157:Transcription Factors; D000097983:ERRalpha Estrogen-Related Receptor; C486497:PPARGC1A protein, human; C111264:peroxisome-proliferator-activated receptor-gamma coactivator-1