title: Down-regulation of the Trk-B signal pathway: the possible pathogenesis of major depression.
mesh_terms: D001921:Brain / Q000378:metabolism*; D019208:Brain-Derived Neurotrophic Factor / Q000378:metabolism*; D003865:Major Depressive Disorder / Q000378:metabolism*; D015536:Down-Regulation; D006801:Humans; D008954:Models, Biological; D020794:Receptor Protein-Tyrosine Kinases / Q000378:metabolism*; D020813:Receptor, trkB / Q000378:metabolism*; D015398:Signal Transduction; D013312:Stress, Physiological / Q000150:complications / Q000378:metabolism*
chemical_list: D019208:Brain-Derived Neurotrophic Factor; D020794:Receptor Protein-Tyrosine Kinases; D020813:Receptor, trkB