Interactions of HIV-1 proteins gp120 and Nef with cellular partners define a novel allosteric paradigm.
D000494:Allosteric Regulation; D000495:Allosteric Site; D000818:Animals; D015704:CD4 Antigens / Q000378:metabolism; D002152:Calorimetry, Differential Scanning; D015195:Drug Design; D015693:Gene Products, nef / Q000737:chemistry* / Q000378:metabolism*; D015699:HIV Envelope Protein gp120 / Q000737:chemistry* / Q000378:metabolism*; D015658:HIV Infections / Q000188:drug therapy; D015497:HIV-1 / Q000187:drug effects / Q000378:metabolism*; D006801:Humans; D013696:Temperature; D013816:Thermodynamics; D054311:nef Gene Products, Human Immunodeficiency Virus; D018909:src Homology Domains / Q000502:physiology
D015704:CD4 Antigens; D015693:Gene Products, nef; D015699:HIV Envelope Protein gp120; D054311:nef Gene Products, Human Immunodeficiency Virus