Partial reconstruction of in vitro gluconeogenesis arising from mitochondrial l-lactate uptake/metabolism and oxaloacetate export via novel L-lactate translocators.
D000818:Animals; D000968:Antimycin A / Q000494:pharmacology; D001692:Biological Transport / Q000187:drug effects; D002259:Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone / Q000494:pharmacology; D002474:Cell-Free System; D003486:Cyanides / Q000494:pharmacology; D005943:Gluconeogenesis; D005986:Glyceraldehyde 3-Phosphate / Q000096:biosynthesis; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D019344:Lactic Acid / Q000378:metabolism*; D008293:Malates / Q000378:metabolism; D008297:Male; D008930:Mitochondria, Liver / Q000378:metabolism*; D008954:Models, Biological; D027501:Monocarboxylic Acid Transporters / Q000378:metabolism*; D009997:Osmotic Pressure; D062907:Oxaloacetic Acid / Q000378:metabolism*; D010084:Oxidation-Reduction; D010619:Phenazines / Q000494:pharmacology; D011522:Protons; D019289:Pyruvic Acid / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D012402:Rotenone / Q000494:pharmacology; D013386:Succinates / Q000494:pharmacology; D013772:Tetramethylphenylenediamine / Q000494:pharmacology; D014475:Uncoupling Agents / Q000494:pharmacology
D003486:Cyanides; D008293:Malates; D027501:Monocarboxylic Acid Transporters; D010619:Phenazines; D011522:Protons; D013386:Succinates; D014475:Uncoupling Agents; D012402:Rotenone; D005986:Glyceraldehyde 3-Phosphate; D062907:Oxaloacetic Acid; D019344:Lactic Acid; D002259:Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; C017625:2-phenylsuccinate; D000968:Antimycin A; C030298:malic acid; D019289:Pyruvic Acid; D007770:L-Lactate Dehydrogenase; D013772:Tetramethylphenylenediamine; C009195:safranine T