Glutathione is involved in the antimalarial action of chloroquine and its modulation affects drug sensitivity of human and murine species of Plasmodium.
D000111:Acetylcysteine / Q000494:pharmacology; D000655:Amodiaquine / Q000494:pharmacology; D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D002738:Chloroquine / Q000494:pharmacology*; D004351:Drug Resistance; D005978:Glutathione / Q000378:metabolism*; D006427:Hemin / Q000378:metabolism; D006801:Humans; D008288:Malaria / Q000188:drug therapy; D051379:Mice; D010961:Plasmodium / Q000187:drug effects*
D000962:Antimalarials; D000655:Amodiaquine; D006427:Hemin; D002738:Chloroquine; D005978:Glutathione; D000111:Acetylcysteine