title: Enhanced antidepressant efficacy of sigma1 receptor agonists in rats after chronic intracerebroventricular infusion of beta-amyloid-(1-40) protein.
mesh_terms: D000544:Alzheimer Disease / Q000139:chemically induced / Q000378:metabolism / Q000523:psychology; D016229:Amyloid beta-Peptides / Q000008:administration & dosage; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D002934:Cinnamates / Q000494:pharmacology*; D003213:Conditioning, Psychological / Q000187:drug effects; D003521:Cyclopropanes / Q000494:pharmacology*; D003687:Dehydroepiandrosterone / Q000378:metabolism / Q000494:pharmacology*; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005239:Fear / Q000187:drug effects / Q000523:psychology; D007276:Injections, Intraventricular; D008297:Male; D010446:Peptide Fragments / Q000008:administration & dosage; D010620:Phenazocine / Q000031:analogs & derivatives* / Q000494:pharmacology*; D011284:Pregnenolone / Q000378:metabolism; D011374:Progesterone / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D017480:Receptors, sigma / Q000819:agonists*; D013315:Stress, Psychological / Q000378:metabolism / Q000523:psychology; D000097605:Sigma-1 Receptor
chemical_list: D016229:Amyloid beta-Peptides; D000928:Antidepressive Agents; D002934:Cinnamates; D003521:Cyclopropanes; D003687:Dehydroepiandrosterone; D010446:Peptide Fragments; D010620:Phenazocine; D011284:Pregnenolone; D011374:Progesterone; D017480:Receptors, sigma; D000097605:Sigma-1 Receptor; C078592:amyloid beta-protein (1-40); C012134:SK&F 10047; C065310:igmesine