Apoptosis induced by staurosporine in ECV304 cells requires cell shrinkage and upregulation of Cl- conductance.
D017209:Apoptosis / Q000187:drug effects*; D048429:Cell Size / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D018118:Chloride Channels / Q000037:antagonists & inhibitors / Q000378:metabolism; D002713:Chlorine / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D018408:Patch-Clamp Techniques; D015221:Potassium Channels / Q000378:metabolism; D019311:Staurosporine / Q000494:pharmacology*
D018118:Chloride Channels; D004791:Enzyme Inhibitors; D015221:Potassium Channels; D002713:Chlorine; D019311:Staurosporine