The neuropeptide secretoneurin acts as a direct angiogenic cytokine in vitro and in vivo.
D043925:Angiogenesis Inducing Agents / Q000494:pharmacology*; D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D002455:Cell Division; D002478:Cells, Cultured; D003315:Cornea / Q000033:anatomy & histology / Q000098:blood supply; D016207:Cytokines / Q000494:pharmacology; D004730:Endothelium, Vascular / Q000166:cytology / Q000187:drug effects / Q000201:enzymology; D006801:Humans; D051379:Mice; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism; D009479:Neuropeptides / Q000494:pharmacology*; D017346:Protein Serine-Threonine Kinases; D011518:Proto-Oncogene Proteins / Q000378:metabolism; D051057:Proto-Oncogene Proteins c-akt; D053381:Secretogranin II; D015398:Signal Transduction
D043925:Angiogenesis Inducing Agents; D016207:Cytokines; D009479:Neuropeptides; D011518:Proto-Oncogene Proteins; D053381:Secretogranin II; C081159:secretoneurin; C494918:AKT1 protein, human; D017346:Protein Serine-Threonine Kinases; D051057:Proto-Oncogene Proteins c-akt; D020928:Mitogen-Activated Protein Kinases