Expression of constitutively active Notch4 (Int-3) modulates myeloid proliferation and differentiation and promotes expansion of hematopoietic progenitors.
D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D002455:Cell Division; D002460:Cell Line; D018922:HL-60 Cells; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D022423:Myeloid Cells; D038042:Myelopoiesis; D010703:Phorbol Esters / Q000494:pharmacology; D017434:Protein Structure, Tertiary; D011518:Proto-Oncogene Proteins / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D000074562:Receptor, Notch4; D011956:Receptors, Cell Surface; D051880:Receptors, Notch; D014162:Transfection; D014212:Tretinoin / Q000494:pharmacology
C106075:NOTCH4 protein, human; D010703:Phorbol Esters; D011518:Proto-Oncogene Proteins; D000074562:Receptor, Notch4; D011956:Receptors, Cell Surface; D051880:Receptors, Notch; D014212:Tretinoin