title: Mechanism of activation of human heparanase investigated by protein engineering.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D015153:Blotting, Western; D019556:COS Cells; D002522:Chlorocebus aethiops; D003001:Cloning, Molecular; D016384:Consensus Sequence; D010450:Endopeptidases / Q000737:chemistry / Q000235:genetics; D004789:Enzyme Activation / Q000235:genetics; D005822:Genetic Vectors; D005966:Glucuronidase / Q000737:chemistry* / Q000235:genetics*; D006801:Humans; D006868:Hydrolysis; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D017800:Potyvirus / Q000201:enzymology / Q000235:genetics; D017510:Protein Folding; D017433:Protein Structure, Secondary; D017386:Sequence Homology, Amino Acid; D018411:Spodoptera / Q000235:genetics; D014162:Transfection; D014305:Triose-Phosphate Isomerase / Q000737:chemistry; D000099175:Heparanase
chemical_list: D010450:Endopeptidases; D005966:Glucuronidase; D014305:Triose-Phosphate Isomerase; D000099175:Heparanase; C099488:TEV protease