Endoproteolytic activation of alpha(v) integrin by proprotein convertase PC5 is required for vascular smooth muscle cell adhesion to vitronectin and integrin-dependent signaling.
D000818:Animals; D002340:Carotid Artery Diseases / Q000201:enzymology / Q000473:pathology; D002448:Cell Adhesion; D002465:Cell Movement; D002478:Cells, Cultured; D039564:Integrin alphaV / Q000378:metabolism*; D016023:Integrins / Q000378:metabolism*; D009131:Muscle, Smooth, Vascular / Q000166:cytology / Q000201:enzymology / Q000502:physiology*; D045702:Proprotein Convertase 5 / Q000378:metabolism / Q000502:physiology*; D051381:Rats; D015398:Signal Transduction; D019096:Vitronectin / Q000378:metabolism*
D039564:Integrin alphaV; D016023:Integrins; D019096:Vitronectin; D045702:Proprotein Convertase 5; C473807:propeptide convertase 5, rat