title: Toxicokinetic and genomic analysis of chronic arsenic exposure in multidrug-resistance mdr1a/1b(-/-) double knockout mice.
mesh_terms: D018435:ATP Binding Cassette Transporter, Subfamily B / Q000235:genetics* / Q000378:metabolism; D018528:ATP-Binding Cassette Transporters / Q000235:genetics* / Q000378:metabolism; D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001151:Arsenic / Q000493:pharmacokinetics* / Q000633:toxicity*; D001692:Biological Transport / Q000235:genetics; D018432:Drug Resistance, Multiple / Q000187:drug effects / Q000235:genetics / Q000502:physiology; D005786:Gene Expression Regulation / Q000187:drug effects; D005978:Glutathione / Q000187:drug effects / Q000378:metabolism; D005980:Glutathione Reductase / Q000378:metabolism; D007668:Kidney / Q000293:injuries / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000293:injuries / Q000378:metabolism / Q000473:pathology; D051379:Mice; D018345:Mice, Knockout; D009584:Nitrogen / Q000652:urine; D020411:Oligonucleotide Array Sequence Analysis; D000097202:ATP-Binding Cassette Sub-Family B Member 4
chemical_list: D018435:ATP Binding Cassette Transporter, Subfamily B; D018528:ATP-Binding Cassette Transporters; D000410:Alanine Transaminase; D001151:Arsenic; D005978:Glutathione; D005980:Glutathione Reductase; D009584:Nitrogen; D000097202:ATP-Binding Cassette Sub-Family B Member 4; C095122:multidrug resistance protein 3