Biliverdin, a natural product of heme catabolism, induces tolerance to cardiac allografts.
D000818:Animals; D001664:Biliverdine / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D002465:Cell Movement / Q000187:drug effects; D004268:DNA-Binding Proteins / Q000037:antagonists & inhibitors; D006085:Graft Survival / Q000276:immunology; D016027:Heart Transplantation / Q000276:immunology / Q000473:pathology; D006418:Heme / Q000378:metabolism; D007376:Interleukin-2 / Q000096:biosynthesis; D007519:Isoantigens / Q000276:immunology; D008213:Lymphocyte Activation / Q000187:drug effects; D051379:Mice; D016328:NF-kappa B / Q000037:antagonists & inhibitors; D050778:NFATC Transcription Factors; D009687:Nuclear Proteins; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D014157:Transcription Factors / Q000037:antagonists & inhibitors; D023001:Transplantation Tolerance
D004268:DNA-Binding Proteins; D007376:Interleukin-2; D007519:Isoantigens; D016328:NF-kappa B; D050778:NFATC Transcription Factors; D009687:Nuclear Proteins; D014157:Transcription Factors; D006418:Heme; D001664:Biliverdine