Inactivation of class II transactivator by DNA methylation and histone deacetylation associated with absence of HLA-DR induction by interferon-gamma in haematopoietic tumour cells.
D000107:Acetylation; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002470:Cell Survival; D019175:DNA Methylation; D005434:Flow Cytometry; D015972:Gene Expression Regulation, Neoplastic; D005802:Genes, MHC Class II; D006684:HLA-DR Antigens / Q000096:biosynthesis* / Q000276:immunology; D019337:Hematologic Neoplasms / Q000235:genetics* / Q000473:pathology*; D006657:Histones / Q000378:metabolism; D006801:Humans; D007371:Interferon-gamma / Q000494:pharmacology*; D009687:Nuclear Proteins / Q000378:metabolism*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D015534:Trans-Activators / Q000378:metabolism*; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D006684:HLA-DR Antigens; D006657:Histones; C083728:MHC class II transactivator protein; D009687:Nuclear Proteins; D015534:Trans-Activators; D007371:Interferon-gamma