Role of strategic cysteine residues in oxidative damage to the yeast plasma membrane H(+)-ATPase caused by Fe- and Cu-containing Fenton reagents.
D019943:Amino Acid Substitution; D002462:Cell Membrane / Q000187:drug effects / Q000201:enzymology; D003300:Copper; D003545:Cysteine / Q000378:metabolism; D005609:Free Radicals; D006861:Hydrogen Peroxide / Q000494:pharmacology*; D007501:Iron / Q000494:pharmacology*; D009154:Mutation; D018384:Oxidative Stress / Q000187:drug effects*; D006180:Proton-Translocating ATPases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000737:chemistry / Q000187:drug effects / Q000201:enzymology*; D013329:Structure-Activity Relationship
C045076:Fenton's reagent; D005609:Free Radicals; D003300:Copper; D006861:Hydrogen Peroxide; D007501:Iron; D006180:Proton-Translocating ATPases; D003545:Cysteine