Conjugation of amino-containing drugs to polysaccharides by tosylation: amphotericin B-arabinogalactan conjugates.
D000596:Amino Acids / Q000008:administration & dosage / Q000737:chemistry / Q000633:toxicity; D000666:Amphotericin B / Q000008:administration & dosage* / Q000737:chemistry* / Q000633:toxicity; D000818:Animals; D000935:Antifungal Agents / Q000008:administration & dosage / Q000737:chemistry / Q000633:toxicity; D000981:Antiprotozoal Agents / Q000008:administration & dosage / Q000737:chemistry / Q000633:toxicity; D002176:Candida albicans / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D016503:Drug Delivery Systems / Q000379:methods*; D004341:Drug Evaluation; D004355:Drug Stability; D005685:Galactans / Q000008:administration & dosage* / Q000737:chemistry* / Q000633:toxicity; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D018320:Leishmania major / Q000187:drug effects*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008968:Molecular Conformation; D014677:Pharmaceutical Vehicles; D011134:Polysaccharides / Q000008:administration & dosage / Q000737:chemistry / Q000633:toxicity; D012756:Sheep; D012995:Solubility; D013534:Survival; D014867:Water / Q000737:chemistry
D000596:Amino Acids; D000935:Antifungal Agents; D000981:Antiprotozoal Agents; D005685:Galactans; D014677:Pharmaceutical Vehicles; D011134:Polysaccharides; D014867:Water; D000666:Amphotericin B; C005653:arabinogalactan