Activation of Syk in neutrophils by antineutrophil cytoplasm antibodies occurs via Fcgamma receptors and CD18.
D019268:Antibodies, Antineutrophil Cytoplasmic / Q000276:immunology*; D018821:CD18 Antigens / Q000187:drug effects / Q000276:immunology*; D002118:Calcium / Q000378:metabolism; D004792:Enzyme Precursors / Q000276:immunology* / Q000378:metabolism; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D018375:Neutrophil Activation / Q000276:immunology*; D010766:Phosphorylation / Q000187:drug effects; D011505:Protein-Tyrosine Kinases / Q000276:immunology* / Q000378:metabolism; D011743:Pyrimidines / Q000494:pharmacology; D017452:Receptors, IgG / Q000276:immunology*; D000072377:Syk Kinase; D019061:src-Family Kinases / Q000502:physiology
C412373:AG 1879; D019268:Antibodies, Antineutrophil Cytoplasmic; D018821:CD18 Antigens; D004792:Enzyme Precursors; D047908:Intracellular Signaling Peptides and Proteins; D011743:Pyrimidines; D017452:Receptors, IgG; D011505:Protein-Tyrosine Kinases; C000606896:SYK protein, human; D000072377:Syk Kinase; D019061:src-Family Kinases; D002118:Calcium