Effect of FK506 on donor T-cell functions that are responsible for graft-versus-host disease and graft-versus-leukemia effect.
D000818:Animals; D000943:Antigens, Differentiation / Q000235:genetics; D002455:Cell Division / Q000187:drug effects; D010450:Endopeptidases / Q000235:genetics; D053222:Fas Ligand Protein; D006086:Graft vs Host Disease / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D020544:Graft vs Leukemia Effect / Q000187:drug effects / Q000502:physiology*; D053804:Granzymes; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D008562:Membrane Glycoproteins / Q000235:genetics; D051379:Mice; D008815:Mice, Inbred Strains; D012333:RNA, Messenger / Q000378:metabolism; D013601:T-Lymphocytes / Q000166:cytology / Q000187:drug effects* / Q000502:physiology*; D016559:Tacrolimus / Q000494:pharmacology*; D014019:Tissue Donors; D015854:Up-Regulation
D000943:Antigens, Differentiation; C505661:FASLG protein, human; D053222:Fas Ligand Protein; C505658:Fasl protein, mouse; D007166:Immunosuppressive Agents; D008562:Membrane Glycoproteins; D012333:RNA, Messenger; D010450:Endopeptidases; C509213:GZMB protein, human; D053804:Granzymes; C509214:Gzmb protein, mouse; D016559:Tacrolimus