TIAF1 and p53 functionally interact in mediating apoptosis and silencing of TIAF1 abolishes nuclear translocation of serine 15-phosphorylated p53.
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D051017:Apoptosis Regulatory Proteins; D002352:Carrier Proteins / Q000378:metabolism*; D002455:Cell Division; D002467:Cell Nucleus / Q000378:metabolism*; D020868:Gene Silencing; D006801:Humans; D007739:L Cells; D051379:Mice; D018995:Myosin Heavy Chains / Q000378:metabolism*; D009218:Myosins / Q000378:metabolism*; D009687:Nuclear Proteins; D010766:Phosphorylation; D010768:Phosphoserine / Q000378:metabolism; D021381:Protein Transport; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D014162:Transfection; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism*; D020298:U937 Cells
D051017:Apoptosis Regulatory Proteins; D002352:Carrier Proteins; D018995:Myosin Heavy Chains; D009218:Myosins; D009687:Nuclear Proteins; D010768:Phosphoserine; D011993:Recombinant Fusion Proteins; D016159:Tumor Suppressor Protein p53; C407101:Myo18a protein, mouse; C407152:MYO18A protein, human