The higher expression of alpha and beta isoforms of the human glucocorticoid receptor in leukemic B-progenitors compared to normal CD10+ BM cells does not correlate with methylprednisolone-induced apoptosis.
D017209:Apoptosis / Q000187:drug effects*; D001402:B-Lymphocytes / Q000187:drug effects / Q000473:pathology; D001854:Bone Marrow Cells / Q000187:drug effects; D016022:Case-Control Studies; D006801:Humans; D008775:Methylprednisolone / Q000494:pharmacology*; D014411:Neoplastic Stem Cells / Q000187:drug effects / Q000473:pathology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000473:pathology*; D011379:Prognosis; D020033:Protein Isoforms / Q000032:analysis; D011965:Receptors, Glucocorticoid / Q000032:analysis*; D014407:Tumor Cells, Cultured
D020033:Protein Isoforms; D011965:Receptors, Glucocorticoid; D008775:Methylprednisolone