Mycobacterial purified protein derivatives stimulate innate immunity: Malawians show enhanced tumor necrosis factor alpha, interleukin-1beta (IL-1beta), and IL-10 responses compared to those of adolescents in the United Kingdom.
D000222:Adaptation, Physiological; D000293:Adolescent; D000328:Adult; D001500:BCG Vaccine / Q000008:administration & dosage*; D002648:Child; D006801:Humans; D007113:Immunity, Innate; D007375:Interleukin-1 / Q000096:biosynthesis*; D016753:Interleukin-10 / Q000096:biosynthesis*; D008070:Lipopolysaccharides / Q000008:administration & dosage / Q000302:isolation & purification; D008295:Malawi; D014373:Tuberculin / Q000008:administration & dosage* / Q000302:isolation & purification; D014376:Tuberculosis / Q000276:immunology / Q000517:prevention & control; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis*; D006113:United Kingdom
D001500:BCG Vaccine; D007375:Interleukin-1; D008070:Lipopolysaccharides; D014373:Tuberculin; D014409:Tumor Necrosis Factor-alpha; C050016:lipoarabinomannan; D016753:Interleukin-10