Growth factor deprivation induces an alternative non-apoptotic death mechanism that is inhibited by Bcl2 in cells derived from neural precursor cells.
D000225:Adenine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000590:Amino Acid Chloromethyl Ketones / Q000494:pharmacology; D000818:Animals; D017209:Apoptosis / Q000187:drug effects / Q000502:physiology; D051017:Apoptosis Regulatory Proteins; D001343:Autophagy / Q000187:drug effects / Q000502:physiology; D000071186:Beclin-1; D061945:Caspase Inhibitors; D016923:Cell Death / Q000187:drug effects / Q000502:physiology; D002454:Cell Differentiation / Q000187:drug effects / Q000502:physiology; D002470:Cell Survival / Q000187:drug effects / Q000502:physiology; D002867:Chromones / Q000494:pharmacology; D003513:Cycloheximide / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000494:pharmacology; D004815:Epidermal Growth Factor / Q000494:pharmacology; D016222:Fibroblast Growth Factor 2 / Q000172:deficiency / Q000494:pharmacology / Q000502:physiology*; D005786:Gene Expression Regulation / Q000235:genetics; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D049452:Green Fluorescent Proteins; D007150:Immunohistochemistry; D007381:Intermediate Filament Proteins / Q000032:analysis; D008164:Luminescent Proteins / Q000235:genetics; D008636:Mesencephalon / Q000166:cytology; D051379:Mice; D008854:Microscopy, Electron; D009025:Morpholines / Q000494:pharmacology; D009419:Nerve Tissue Proteins / Q000032:analysis; D064231:Nestin; D009474:Neurons / Q000166:cytology* / Q000187:drug effects / Q000502:physiology; D011506:Proteins / Q000235:genetics; D011518:Proto-Oncogene Proteins / Q000235:genetics / Q000502:physiology*; D019253:Proto-Oncogene Proteins c-bcl-2; D013234:Stem Cells / Q000166:cytology* / Q000187:drug effects / Q000502:physiology; D014170:Transformation, Genetic / Q000235:genetics; D014404:Tubulin / Q000032:analysis; D014617:Vacuoles / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure
D000590:Amino Acid Chloromethyl Ketones; D051017:Apoptosis Regulatory Proteins; D000071186:Beclin-1; C115010:Becn1 protein, mouse; D061945:Caspase Inhibitors; D002867:Chromones; D004791:Enzyme Inhibitors; D005904:Glial Fibrillary Acidic Protein; D007381:Intermediate Filament Proteins; D008164:Luminescent Proteins; D009025:Morpholines; D009419:Nerve Tissue Proteins; C577485:Nes protein, mouse; D064231:Nestin; D011506:Proteins; D011518:Proto-Oncogene Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D014404:Tubulin; C096713:benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone; D016222:Fibroblast Growth Factor 2; C052617:Bcl2 protein, mouse; D049452:Green Fluorescent Proteins; C085911:2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one; C025946:3-methyladenine; D004815:Epidermal Growth Factor; D003513:Cycloheximide; D000225:Adenine