Mice deficient for soluble adenylyl cyclase are infertile because of a severe sperm-motility defect.
D000262:Adenylyl Cyclases / Q000172:deficiency* / Q000235:genetics*; D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism; D017931:DNA Primers; D005260:Female; D005306:Fertilization / Q000235:genetics; D005307:Fertilization in Vitro; D017930:Genes, Reporter; D007248:Infertility, Male / Q000235:genetics*; D008297:Male; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D009865:Oocytes / Q000502:physiology; D016133:Polymerase Chain Reaction; D013081:Sperm Motility / Q000235:genetics*; D013094:Spermatozoa / Q000201:enzymology; D013737:Testis / Q000201:enzymology; D001616:beta-Galactosidase / Q000235:genetics
D017931:DNA Primers; D000242:Cyclic AMP; D001616:beta-Galactosidase; D000262:Adenylyl Cyclases