Accumulation of 8-oxo-2'-deoxyguanosine (as a biomarker of oxidative DNA damage) in the tissues of aged hamsters and change in antioxidant enzyme activities after single administration of N-nitrosobis(2-oxopropyl) amine.
D000080242:8-Hydroxy-2'-Deoxyguanosine; D000367:Age Factors; D000818:Animals; D015415:Biomarkers / Q000032:analysis; D002374:Catalase / Q000378:metabolism; D006224:Cricetinae; D003849:Deoxyguanosine / Q000031:analogs & derivatives* / Q000378:metabolism*; D005260:Female; D005979:Glutathione Peroxidase / Q000378:metabolism; D007279:Injections, Subcutaneous; D008647:Mesocricetus; D009153:Mutagens / Q000493:pharmacokinetics*; D009602:Nitrosamines / Q000493:pharmacokinetics*; D013482:Superoxide Dismutase / Q000378:metabolism; D014018:Tissue Distribution
D015415:Biomarkers; D009153:Mutagens; D009602:Nitrosamines; C013622:nitrosobis(2-oxopropyl)amine; D000080242:8-Hydroxy-2'-Deoxyguanosine; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D003849:Deoxyguanosine