title: Lead optimization of antifungal peptides with 3D NMR structures analysis.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000935:Antifungal Agents / Q000737:chemistry* / Q000494:pharmacology; D023181:Antimicrobial Cationic Peptides / Q000737:chemistry* / Q000235:genetics / Q000494:pharmacology; D001232:Aspergillus fumigatus / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D003001:Cloning, Molecular; D003455:Cryptococcus neoformans / Q000187:drug effects; D015195:Drug Design; D005670:Fusarium / Q000187:drug effects; D006458:Hemolymph / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D019476:Insect Proteins / Q000737:chemistry / Q000302:isolation & purification; D007814:Larva / Q000737:chemistry; D007915:Lepidoptera / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed / Q000235:genetics; D019906:Nuclear Magnetic Resonance, Biomolecular; D011487:Protein Conformation; D017433:Protein Structure, Secondary; D011994:Recombinant Proteins / Q000235:genetics / Q000302:isolation & purification / Q000494:pharmacology; D021681:Scedosporium / Q000187:drug effects; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D055672:Static Electricity; D040681:Structural Homology, Protein; D013329:Structure-Activity Relationship; D013499:Surface Properties
chemical_list: D000935:Antifungal Agents; D023181:Antimicrobial Cationic Peptides; D019476:Insect Proteins; D011994:Recombinant Proteins