Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase.
D000577:Amides / Q000627:therapeutic use; D000818:Animals; D006332:Cardiomegaly / Q000503:physiopathology; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D006400:Hematocrit; D006976:Hypertension, Pulmonary / Q000517:prevention & control*; D000860:Hypoxia; D066298:In Vitro Techniques; D047908:Intracellular Signaling Peptides and Proteins; D008168:Lung / Q000187:drug effects / Q000502:physiology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D010477:Perfusion; D017346:Protein Serine-Threonine Kinases / Q000037:antagonists & inhibitors*; D011652:Pulmonary Circulation / Q000187:drug effects / Q000502:physiology*; D011725:Pyridines / Q000627:therapeutic use; D014661:Vasoconstriction / Q000187:drug effects*; D018497:Ventricular Dysfunction, Right / Q000473:pathology / Q000503:physiopathology; D016278:Ventricular Function, Right / Q000187:drug effects / Q000502:physiology; D054460:rho-Associated Kinases
D000577:Amides; D004791:Enzyme Inhibitors; D047908:Intracellular Signaling Peptides and Proteins; D011725:Pyridines; C108830:Y 27632; D017346:Protein Serine-Threonine Kinases; D054460:rho-Associated Kinases