Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids.
D000818:Animals; D001667:Binding, Competitive; D027682:Cation Transport Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D003110:Colonic Neoplasms / Q000378:metabolism* / Q000503:physiopathology*; D015536:Down-Regulation; D004563:Electrochemistry; D005232:Fatty Acids, Volatile / Q000378:metabolism*; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007454:Iodides / Q000378:metabolism; D008564:Membrane Potentials / Q000502:physiology; D027501:Monocarboxylic Acid Transporters; D009865:Oocytes / Q000502:physiology; D018408:Patch-Clamp Techniques; D012333:RNA, Messenger / Q000032:analysis; D012964:Sodium / Q000378:metabolism; D014981:Xenopus
D027682:Cation Transport Proteins; D005232:Fatty Acids, Volatile; D007454:Iodides; D027501:Monocarboxylic Acid Transporters; D012333:RNA, Messenger; C476760:SLC5A8 protein, human; D012964:Sodium