Protective effects of endogenous adrenomedullin on cardiac hypertrophy, fibrosis, and renal damage.
D053607:Adrenomedullin; D000804:Angiotensin II / Q000633:toxicity; D000808:Angiotensinogen / Q000096:biosynthesis / Q000235:genetics; D000818:Animals; D001012:Aorta, Abdominal; D006332:Cardiomegaly / Q000209:etiology / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology; D024042:Collagen Type I / Q000096:biosynthesis / Q000235:genetics; D003250:Constriction; D004789:Enzyme Activation; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005347:Fibroblasts / Q000473:pathology; D005355:Fibrosis; D005786:Gene Expression Regulation; D005804:Genes, Lethal; D016762:Genes, fos; D005923:Glomerulosclerosis, Focal Segmental / Q000209:etiology / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology; D006579:Heterozygote; D020935:MAP Kinase Signaling System / Q000187:drug effects; D008297:Male; D051379:Mice; D018345:Mice, Knockout; D019950:Mitogen-Activated Protein Kinase 1 / Q000378:metabolism; D048052:Mitogen-Activated Protein Kinase 3; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism; D032383:Myocytes, Cardiac / Q000378:metabolism / Q000473:pathology; D020097:Natriuretic Peptide, Brain / Q000096:biosynthesis / Q000235:genetics; D010455:Peptides / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D007703:Peptidyl-Dipeptidase A / Q000096:biosynthesis / Q000235:genetics; D011493:Protein Kinase C / Q000037:antagonists & inhibitors; D016760:Proto-Oncogene Proteins c-fos / Q000096:biosynthesis; D016212:Transforming Growth Factor beta / Q000096:biosynthesis / Q000235:genetics; D020257:Ventricular Remodeling / Q000502:physiology
D024042:Collagen Type I; D004791:Enzyme Inhibitors; D010455:Peptides; D016760:Proto-Oncogene Proteins c-fos; D016212:Transforming Growth Factor beta; D000808:Angiotensinogen; D000804:Angiotensin II; D020097:Natriuretic Peptide, Brain; D053607:Adrenomedullin; D011493:Protein Kinase C; D019950:Mitogen-Activated Protein Kinase 1; D048052:Mitogen-Activated Protein Kinase 3; D020928:Mitogen-Activated Protein Kinases; D007703:Peptidyl-Dipeptidase A