title: Cholesterol 7alpha-hydroxylase deficiency in mice on an APOE*3-Leiden background impairs very-low-density lipoprotein production.
mesh_terms: D000217:Acyltransferases / Q000378:metabolism; D000818:Animals; D053318:Apolipoprotein E3; D001055:Apolipoproteins B / Q000378:metabolism; D001057:Apolipoproteins E / Q000235:genetics*; D001647:Bile Acids and Salts / Q000378:metabolism*; D002790:Cholesterol 7-alpha-Hydroxylase / Q000172:deficiency* / Q000235:genetics / Q000502:physiology; D002788:Cholesterol Esters / Q000378:metabolism; D003433:Crosses, Genetic; D051048:Diacylglycerol O-Acyltransferase; D004036:Diet, Atherogenic; D005243:Feces; D005260:Female; D006952:Hyperlipoproteinemia Type III / Q000235:genetics / Q000378:metabolism; D007657:Ketone Bodies / Q000378:metabolism; D050356:Lipid Metabolism; D008066:Lipolysis; D008079:Lipoproteins, VLDL / Q000096:biosynthesis* / Q000097:blood; D008099:Liver / Q000378:metabolism; D008297:Male; D051379:Mice; D018345:Mice, Knockout; D012333:RNA, Messenger / Q000096:biosynthesis; D013261:Sterols / Q000378:metabolism; D014280:Triglycerides / Q000378:metabolism; D014801:Vitamin A / Q000378:metabolism; D014810:Vitamin E / Q000378:metabolism
chemical_list: D053318:Apolipoprotein E3; D001055:Apolipoproteins B; D001057:Apolipoproteins E; D001647:Bile Acids and Salts; D002788:Cholesterol Esters; D007657:Ketone Bodies; D008079:Lipoproteins, VLDL; D012333:RNA, Messenger; D013261:Sterols; D014280:Triglycerides; C052720:apolipoprotein E3 (Leidein); D014801:Vitamin A; D014810:Vitamin E; D002790:Cholesterol 7-alpha-Hydroxylase; D000217:Acyltransferases; C494882:Dgat1 protein, mouse; D051048:Diacylglycerol O-Acyltransferase