title: Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis.
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D017209:Apoptosis / Q000187:drug effects* / Q000502:physiology; D001647:Bile Acids and Salts / Q000009:adverse effects*; D001973:Bromodeoxyuridine / Q000378:metabolism; D053453:Caspase 9; D020169:Caspases / Q000187:drug effects / Q000378:metabolism; D002453:Cell Cycle / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D002463:Cell Membrane Permeability / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects* / Q000502:physiology; D002635:Chenodeoxycholic Acid / Q000494:pharmacology; D002843:Chromatin / Q000187:drug effects / Q000378:metabolism; D045304:Cytochromes c / Q000187:drug effects / Q000378:metabolism; D004247:DNA / Q000096:biosynthesis / Q000187:drug effects; D053938:DNA Fragmentation; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D006801:Humans; D028361:Mitochondrial Diseases / Q000503:physiopathology*; D009336:Necrosis; D011065:Poly(ADP-ribose) Polymerases / Q000187:drug effects / Q000378:metabolism; D013655:Taurochenodeoxycholic Acid / Q000494:pharmacology; D013997:Time Factors; D014404:Tubulin / Q000187:drug effects / Q000378:metabolism; D014580:Ursodeoxycholic Acid / Q000494:pharmacology
chemical_list: D001647:Bile Acids and Salts; D002843:Chromatin; D014404:Tubulin; D002635:Chenodeoxycholic Acid; D013655:Taurochenodeoxycholic Acid; C031655:ursodoxicoltaurine; D014580:Ursodeoxycholic Acid; D000255:Adenosine Triphosphate; D045304:Cytochromes c; D004247:DNA; D011065:Poly(ADP-ribose) Polymerases; C506433:CASP9 protein, human; D053453:Caspase 9; D020169:Caspases; D001973:Bromodeoxyuridine