Ectopic expression of the catalytic subunit of telomerase protects against brain injury resulting from ischemia and NMDA-induced neurotoxicity.
D000818:Animals; D020208:Brain Injury, Chronic / Q000139:chemically induced / Q000235:genetics / Q000517:prevention & control*; D002545:Brain Ischemia / Q000235:genetics / Q000628:therapy*; D002118:Calcium / Q000378:metabolism; D002478:Cells, Cultured; D018920:Coculture Techniques; D004268:DNA-Binding Proteins; D004195:Disease Models, Animal; D018690:Excitatory Amino Acid Agonists; D005456:Fluorescent Dyes; D005786:Gene Expression Regulation; D020925:Hypoxia-Ischemia, Brain / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control; D008564:Membrane Potentials / Q000187:drug effects / Q000235:genetics; D051379:Mice; D008822:Mice, Transgenic; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism; D016202:N-Methylaspartate; D009457:Neuroglia / Q000166:cytology; D009474:Neurons / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D020258:Neurotoxicity Syndromes / Q000209:etiology / Q000517:prevention & control*; D009498:Neurotoxins; D012333:RNA, Messenger / Q000096:biosynthesis; D019098:Telomerase / Q000096:biosynthesis* / Q000235:genetics
D004268:DNA-Binding Proteins; D018690:Excitatory Amino Acid Agonists; D005456:Fluorescent Dyes; D009498:Neurotoxins; D012333:RNA, Messenger; D016202:N-Methylaspartate; D019098:Telomerase; C509187:Tert protein, mouse; D002118:Calcium