title: Frequent loss of the AXIN1 locus but absence of AXIN1 gene mutations in adenocarcinomas of the gastro-oesophageal junction with nuclear beta-catenin expression.
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics* / Q000503:physiopathology; D060466:Axin Protein; D015820:Cadherins; D003598:Cytoskeletal Proteins / Q000096:biosynthesis*; D004252:DNA Mutational Analysis; D004938:Esophageal Neoplasms / Q000235:genetics* / Q000503:physiopathology; D018628:Gene Dosage; D006801:Humans; D007150:Immunohistochemistry; D019656:Loss of Heterozygosity; D011505:Protein-Tyrosine Kinases / Q000494:pharmacology; D011518:Proto-Oncogene Proteins / Q000494:pharmacology; D012097:Repressor Proteins / Q000096:biosynthesis / Q000235:genetics*; D015398:Signal Transduction; D013274:Stomach Neoplasms / Q000235:genetics* / Q000503:physiopathology; D015534:Trans-Activators / Q000096:biosynthesis*; D014407:Tumor Cells, Cultured; D051153:Wnt Proteins; D029961:Zebrafish Proteins; D051176:beta Catenin
chemical_list: C555451:AXIN1 protein, human; D060466:Axin Protein; C495270:CTNNB1 protein, human; D015820:Cadherins; D003598:Cytoskeletal Proteins; D011518:Proto-Oncogene Proteins; D012097:Repressor Proteins; D015534:Trans-Activators; D051153:Wnt Proteins; D029961:Zebrafish Proteins; D051176:beta Catenin; D011505:Protein-Tyrosine Kinases