Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA.
D015152:Blotting, Northern; D018797:Cell Cycle Proteins; D005838:Genotype; D006801:Humans; D010957:Plasmids; D021122:Protein Subunits; D012313:RNA / Q000235:genetics / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics; D019098:Telomerase / Q000037:antagonists & inhibitors* / Q000172:deficiency; D025521:Tumor Suppressor Proteins / Q000235:genetics / Q000378:metabolism*
D018797:Cell Cycle Proteins; C440808:PINX1 protein, human; D021122:Protein Subunits; D029701:Saccharomyces cerevisiae Proteins; D025521:Tumor Suppressor Proteins; D012313:RNA; D019098:Telomerase