A role for Toll-like receptor 4 in dendritic cell activation and cytolytic CD8+ T cell differentiation in response to a recombinant heat shock fusion protein.
D000818:Animals; D001426:Bacterial Proteins / Q000008:administration & dosage / Q000502:physiology*; D002454:Cell Differentiation / Q000276:immunology; D018834:Chaperonin 60; D018833:Chaperonins / Q000008:administration & dosage / Q000502:physiology*; D003602:Cytotoxicity, Immunologic / Q000235:genetics; D003713:Dendritic Cells / Q000187:drug effects / Q000276:immunology* / Q000378:metabolism*; D004306:Dose-Response Relationship, Immunologic; D019286:Endopeptidase K / Q000494:pharmacology; D020869:Gene Expression Profiling; D008070:Lipopolysaccharides / Q000008:administration & dosage; D008213:Lymphocyte Activation / Q000235:genetics / Q000276:immunology; D008562:Membrane Glycoproteins / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D051379:Mice; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D020411:Oligonucleotide Array Sequence Analysis; D011112:Polymyxin B / Q000494:pharmacology; D011956:Receptors, Cell Surface / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D011993:Recombinant Fusion Proteins / Q000008:administration & dosage / Q000502:physiology*; D013602:T-Lymphocytes, Cytotoxic / Q000166:cytology / Q000276:immunology* / Q000378:metabolism*; D051197:Toll-Like Receptor 4; D051193:Toll-Like Receptors; D015854:Up-Regulation / Q000235:genetics / Q000276:immunology
D001426:Bacterial Proteins; D018834:Chaperonin 60; D008070:Lipopolysaccharides; D008562:Membrane Glycoproteins; D011956:Receptors, Cell Surface; D011993:Recombinant Fusion Proteins; D051197:Toll-Like Receptor 4; D051193:Toll-Like Receptors; C074119:heat-shock protein 65, Mycobacterium; D019286:Endopeptidase K; D018833:Chaperonins; D011112:Polymyxin B