Phosphoinositide 3-kinase signaling is essential for ABL oncogene-mediated transformation of B-lineage cells.
D000818:Animals; D001402:B-Lymphocytes / Q000502:physiology*; D002455:Cell Division / Q000276:immunology; D019070:Cell Lineage / Q000276:immunology; D002471:Cell Transformation, Neoplastic / Q000378:metabolism*; D005260:Female; D000071161:Forkhead Box Protein O1; D051858:Forkhead Transcription Factors; D007938:Leukemia / Q000503:physiopathology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D019869:Phosphatidylinositol 3-Kinases / Q000235:genetics / Q000378:metabolism*; D011247:Pregnancy; D011494:Protein Kinases / Q000378:metabolism; D016315:Proto-Oncogene Proteins c-abl / Q000235:genetics*; D015398:Signal Transduction / Q000502:physiology*; D058570:TOR Serine-Threonine Kinases; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism
D000071161:Forkhead Box Protein O1; D051858:Forkhead Transcription Factors; D019869:Phosphatidylinositol 3-Kinases; D011494:Protein Kinases; D016315:Proto-Oncogene Proteins c-abl; D058570:TOR Serine-Threonine Kinases; D014157:Transcription Factors; C467200:Foxo1 protein, mouse; C546842:MTOR protein, human; C546843:mTOR protein, mouse