A covalently linked recombinant albumin dimer is more rapidly cleared in vivo than are wild-type and mutant C34A albumin.
D000409:Alanine; D019943:Amino Acid Substitution; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D003545:Cysteine; D017931:DNA Primers; D019281:Dimerization; D008657:Metabolic Clearance Rate; D016297:Mutagenesis, Site-Directed; D010843:Pichia / Q000235:genetics; D010957:Plasmids; D016133:Polymerase Chain Reaction; D011817:Rabbits; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012709:Serum Albumin / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism
D017931:DNA Primers; D011994:Recombinant Proteins; D012709:Serum Albumin; D003545:Cysteine; D000409:Alanine