Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis.
D000690:Amyotrophic Lateral Sclerosis / Q000276:immunology* / Q000473:pathology / Q000503:physiopathology*; D000818:Animals; D001369:Axons / Q000473:pathology; D001921:Brain / Q000378:metabolism / Q000473:pathology; D004195:Disease Models, Animal; D018450:Disease Progression; D015870:Gene Expression / Q000276:immunology; D007113:Immunity, Innate / Q000276:immunology*; D007114:Immunization / Q000379:methods*; D008070:Lipopolysaccharides / Q000276:immunology; D008562:Membrane Glycoproteins / Q000235:genetics; D051379:Mice; D008810:Mice, Inbred C57BL; D008818:Mice, Neurologic Mutants; D017628:Microglia / Q000276:immunology; D009046:Motor Neurons / Q000473:pathology; D012333:RNA, Messenger / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000235:genetics; D013116:Spinal Cord / Q000378:metabolism / Q000473:pathology; D013126:Spinal Nerve Roots / Q000378:metabolism / Q000473:pathology; D013482:Superoxide Dismutase / Q000235:genetics / Q000378:metabolism; D015996:Survival Rate; D051195:Toll-Like Receptor 2; D051193:Toll-Like Receptors
D008070:Lipopolysaccharides; D008562:Membrane Glycoproteins; D012333:RNA, Messenger; D011956:Receptors, Cell Surface; D051195:Toll-Like Receptor 2; D051193:Toll-Like Receptors; C470429:SOD1 G37R protein, mouse; D013482:Superoxide Dismutase