Exposure of mouse preimplantation embryos to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters the methylation status of imprinted genes H19 and Igf2.
D000818:Animals; D001483:Base Sequence; D001755:Blastocyst / Q000187:drug effects* / Q000378:metabolism*; D004247:DNA / Q000737:chemistry / Q000235:genetics; D019175:DNA Methylation / Q000187:drug effects; D047108:Embryonic Development / Q000187:drug effects; D004785:Environmental Pollutants / Q000633:toxicity*; D005260:Female; D015870:Gene Expression; D018392:Genomic Imprinting; D007335:Insulin-Like Growth Factor II / Q000235:genetics*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D000072317:Polychlorinated Dibenzodioxins / Q000633:toxicity*; D011247:Pregnancy; D062085:RNA, Long Noncoding; D022661:RNA, Untranslated / Q000235:genetics*
D004785:Environmental Pollutants; C094335:H19 long non-coding RNA; D000072317:Polychlorinated Dibenzodioxins; D062085:RNA, Long Noncoding; D022661:RNA, Untranslated; D007335:Insulin-Like Growth Factor II; D004247:DNA