title: A role for sorting nexin 2 in epidermal growth factor receptor down-regulation: evidence for distinct functions of sorting nexin 1 and 2 in protein trafficking.
mesh_terms: D015536:Down-Regulation; D011992:Endosomes / Q000378:metabolism; D066246:ErbB Receptors / Q000235:genetics / Q000378:metabolism*; D017353:Gene Deletion; D015870:Gene Expression; D020868:Gene Silencing; D006367:HeLa Cells; D006801:Humans; D047468:Immunoprecipitation; D008247:Lysosomes / Q000378:metabolism; D018613:Microscopy, Confocal; D009687:Nuclear Proteins / Q000378:metabolism; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D017354:Point Mutation / Q000235:genetics; D011485:Protein Binding; D025941:Protein Interaction Mapping; D017434:Protein Structure, Tertiary; D021381:Protein Transport / Q000235:genetics; D034741:RNA, Small Interfering / Q000235:genetics; D058305:Sorting Nexins; D035361:Transcription Factor TFIIIB; D033921:Vesicular Transport Proteins / Q000502:physiology*; D020696:rab5 GTP-Binding Proteins / Q000378:metabolism
chemical_list: C427472:BDP1 protein, human; D009687:Nuclear Proteins; D034741:RNA, Small Interfering; C513979:SNX2 protein, human; D058305:Sorting Nexins; D035361:Transcription Factor TFIIIB; D033921:Vesicular Transport Proteins; D019869:Phosphatidylinositol 3-Kinases; D066246:ErbB Receptors; D020696:rab5 GTP-Binding Proteins