Anti-diabetic effects of DA-11004, a synthetic IDPc inhibitor in high fat high sucrose diet-fed C57BL/6J mice.
D000273:Adipose Tissue / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D001786:Blood Glucose / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D003921:Diabetes Mellitus, Experimental / Q000503:physiopathology; D004041:Dietary Fats / Q000008:administration & dosage / Q000009:adverse effects*; D019422:Dietary Sucrose / Q000008:administration & dosage / Q000009:adverse effects*; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D004822:Epididymis; D005230:Fatty Acids, Nonesterified / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000097:blood; D007004:Hypoglycemic Agents / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D007521:Isocitrate Dehydrogenase / Q000037:antagonists & inhibitors* / Q000378:metabolism / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008820:Mice, Obese; D009285:Naphthoquinones / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D010537:Peritoneum; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
C492688:4-aminomethyl-1,2-naphthoquinone; D001786:Blood Glucose; D004041:Dietary Fats; D019422:Dietary Sucrose; D005230:Fatty Acids, Nonesterified; D007004:Hypoglycemic Agents; D009285:Naphthoquinones; D014280:Triglycerides; D007521:Isocitrate Dehydrogenase