Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD.
D000375:Aging / Q000502:physiology; D000595:Amino Acid Sequence; D000818:Animals; D002478:Cells, Cultured; D004705:Endocytosis / Q000187:drug effects*; D006624:Hippocampus / Q000166:cytology / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D007328:Insulin / Q000494:pharmacology*; D036881:Long-Term Synaptic Depression; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics; D009474:Neurons / Q000378:metabolism; D010766:Phosphorylation; D019000:Phosphotyrosine / Q000378:metabolism*; D021122:Protein Subunits / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D018091:Receptors, AMPA / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D016415:Sequence Alignment; D009435:Synaptic Transmission; D013997:Time Factors
D007328:Insulin; D021122:Protein Subunits; D018091:Receptors, AMPA; D019000:Phosphotyrosine