Single-stranded breaks in DNA but not oxidative DNA base damages block transcriptional elongation by RNA polymerase II in HeLa cell nuclear extracts.
D002457:Cell Extracts; D002467:Cell Nucleus; D003596:Cytosine / Q000031:analogs & derivatives*; D004249:DNA Damage; D004260:DNA Repair; D003853:Deoxyribonucleosides / Q000378:metabolism*; D006147:Guanine / Q000031:analogs & derivatives*; D006367:HeLa Cells; D006801:Humans; D010084:Oxidation-Reduction; D011740:Pyrimidine Dimers; D012319:RNA Polymerase II / Q000378:metabolism*; D013698:Templates, Genetic; D013941:Thymine / Q000031:analogs & derivatives*; D014158:Transcription, Genetic
D002457:Cell Extracts; D003853:Deoxyribonucleosides; D011740:Pyrimidine Dimers; C029389:thymine glycol; C024829:8-hydroxyguanine; D006147:Guanine; C017400:5-hydroxycytosine; D003596:Cytosine; D012319:RNA Polymerase II; D013941:Thymine