The ceramide analog, B13, induces apoptosis in prostate cancer cell lines and inhibits tumor growth in prostate cancer xenografts.
D000577:Amides / Q000627:therapeutic use / Q000633:toxicity*; D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use; D017209:Apoptosis / Q000187:drug effects*; D016923:Cell Death / Q000187:drug effects; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D008297:Male; D051379:Mice; D008819:Mice, Nude; D011412:Propanolamines / Q000627:therapeutic use / Q000633:toxicity*; D011471:Prostatic Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D014183:Transplantation, Heterologous
D000577:Amides; D000970:Antineoplastic Agents; C421619:N-(1-(4-nitrophenyl)-1,3-dihydroxyprop-2-yl)tetradecanamide; D011412:Propanolamines