title: Heterogeneous patterns of FLT3 Asp(835) mutations in relapsed de novo acute myeloid leukemia: a comparative analysis of 120 paired diagnostic and relapse bone marrow samples.
mesh_terms: D000328:Adult; D000483:Alleles; D001224:Aspartic Acid / Q000235:genetics* / Q000378:metabolism; D001854:Bone Marrow Cells; D003062:Codon; D004247:DNA / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005091:Exons; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009154:Mutation; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D012333:RNA, Messenger / Q000378:metabolism; D020794:Receptor Protein-Tyrosine Kinases / Q000235:genetics*; D012008:Recurrence; D012680:Sensitivity and Specificity; D017422:Sequence Analysis, DNA; D013997:Time Factors; D051941:fms-Like Tyrosine Kinase 3
chemical_list: D003062:Codon; D011518:Proto-Oncogene Proteins; D012333:RNA, Messenger; D001224:Aspartic Acid; D004247:DNA; C497970:FLT3 protein, human; D020794:Receptor Protein-Tyrosine Kinases; D051941:fms-Like Tyrosine Kinase 3