Altered calcium handling is critically involved in the cardiotoxic effects of chronic beta-adrenergic stimulation.
D000818:Animals; D002118:Calcium / Q000378:metabolism / Q000502:physiology; D020013:Calcium Signaling; D002135:Calcium-Binding Proteins / Q000235:genetics; D006332:Cardiomegaly / Q000473:pathology; D002311:Cardiomyopathy, Dilated / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D005355:Fibrosis; D006801:Humans; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D009200:Myocardial Contraction; D009206:Myocardium / Q000378:metabolism / Q000473:pathology; D011654:Pulmonary Edema / Q000473:pathology; D012333:RNA, Messenger / Q000378:metabolism; D018342:Receptors, Adrenergic, beta-1 / Q000235:genetics / Q000378:metabolism*; D016019:Survival Analysis; D016277:Ventricular Function, Left; D000099211:Phospholamban
D002118:Calcium; D002135:Calcium-Binding Proteins; D012333:RNA, Messenger; D018342:Receptors, Adrenergic, beta-1; D000099211:Phospholamban