title: Proteasomal degradation of the nuclear targeting growth factor midkine.
mesh_terms: D000818:Animals; D019556:COS Cells; D002352:Carrier Proteins / Q000378:metabolism*; D002467:Cell Nucleus / Q000378:metabolism*; D002478:Cells, Cultured; D003546:Cysteine Endopeptidases / Q000378:metabolism*; D016207:Cytokines; D003600:Cytosol / Q000378:metabolism; D004705:Endocytosis; D005347:Fibroblasts / Q000378:metabolism; D019084:Fluorescent Antibody Technique, Indirect; D006133:Growth Substances / Q000378:metabolism; D006801:Humans; D007700:Kinetics; D008247:Lysosomes / Q000378:metabolism; D051379:Mice; D000078792:Midkine; D009097:Multienzyme Complexes / Q000378:metabolism*; D010957:Plasmids / Q000378:metabolism; D046988:Proteasome Endopeptidase Complex; D017434:Protein Structure, Tertiary; D015398:Signal Transduction; D013997:Time Factors; D014162:Transfection; D025801:Ubiquitin / Q000378:metabolism
chemical_list: D002352:Carrier Proteins; D016207:Cytokines; D006133:Growth Substances; D009097:Multienzyme Complexes; D025801:Ubiquitin; D000078792:Midkine; D003546:Cysteine Endopeptidases; D046988:Proteasome Endopeptidase Complex