title: Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.
mesh_terms: D000581:Amidohydrolases / Q000037:antagonists & inhibitors*; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000627:therapeutic use; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017963:Azithromycin / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D004791:Enzyme Inhibitors / Q000493:pharmacokinetics* / Q000494:pharmacology*; D007700:Kinetics; D051379:Mice; D008813:Mice, Inbred ICR; D008826:Microbial Sensitivity Tests; D018482:Muscle, Skeletal / Q000378:metabolism; D009135:Muscular Diseases / Q000188:drug therapy / Q000382:microbiology; D009503:Neutropenia / Q000382:microbiology; D010538:Peritonitis / Q000188:drug therapy; D010879:Piperazines / Q000493:pharmacokinetics* / Q000494:pharmacology*; D011008:Pneumococcal Infections / Q000188:drug therapy / Q000382:microbiology; D011014:Pneumonia / Q000382:microbiology; D013296:Streptococcus pneumoniae / Q000187:drug effects*; D014018:Tissue Distribution
chemical_list: D000900:Anti-Bacterial Agents; C484905:BB81384; D004791:Enzyme Inhibitors; D010879:Piperazines; D019980:Amoxicillin-Potassium Clavulanate Combination; D017963:Azithromycin; D000581:Amidohydrolases; C084507:peptide deformylase