Mechanism-based inactivation of cytochrome P450 3A4 by 4-ipomeanol.
D065609:Cytochrome P-450 CYP1A2 Inhibitors; D051544:Cytochrome P-450 CYP3A; D065607:Cytochrome P-450 Enzyme Inhibitors; D004305:Dose-Response Relationship, Drug; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology; D009249:NADP / Q000494:pharmacology; D013379:Substrate Specificity; D013729:Terpenes / Q000494:pharmacology*
D065609:Cytochrome P-450 CYP1A2 Inhibitors; D065607:Cytochrome P-450 Enzyme Inhibitors; D004791:Enzyme Inhibitors; D013729:Terpenes; D009249:NADP; C104464:CYP3A protein, human; D051544:Cytochrome P-450 CYP3A; C001470:4-ipomeanol