Exceptionally high protection of photocarcinogenesis by topical application of (--)-epigallocatechin-3-gallate in hydrophilic cream in SKH-1 hairless mouse model: relationship to inhibition of UVB-induced global DNA hypomethylation.
D044503:5-Methylcytosine / Q000276:immunology; D000287:Administration, Topical; D000818:Animals; D000911:Antibodies, Monoclonal; D001823:Body Composition / Q000187:drug effects; D002277:Carcinoma / Q000473:pathology / Q000517:prevention & control; D002392:Catechin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D002471:Cell Transformation, Neoplastic / Q000187:drug effects / Q000473:pathology; D019175:DNA Methylation / Q000187:drug effects*; D015254:DNA Modification Methylases / Q000032:analysis / Q000276:immunology; D005260:Female; D008055:Lipids; D051379:Mice; D008812:Mice, Hairless; D009381:Neoplasms, Radiation-Induced / Q000473:pathology / Q000517:prevention & control*; D009823:Ointment Bases / Q000737:chemistry; D010212:Papilloma / Q000473:pathology / Q000517:prevention & control; D011837:Radiation-Protective Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D012878:Skin Neoplasms / Q000473:pathology / Q000517:prevention & control*; D013997:Time Factors; D014466:Ultraviolet Rays / Q000009:adverse effects
D000911:Antibodies, Monoclonal; D008055:Lipids; D009823:Ointment Bases; D011837:Radiation-Protective Agents; D044503:5-Methylcytosine; D002392:Catechin; C045651:epigallocatechin gallate; D015254:DNA Modification Methylases