Functional and molecular characterization of naturally occurring mutations in the oocyte-secreted factors bone morphogenetic protein-15 and growth and differentiation factor-9.
D000818:Animals; D055430:Bone Morphogenetic Protein 15; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D005260:Female; D055429:Growth Differentiation Factor 9; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D015151:Immunoblotting; D036341:Intercellular Signaling Peptides and Proteins / Q000235:genetics* / Q000502:physiology*; D009154:Mutation; D009865:Oocytes / Q000378:metabolism*; D010053:Ovary / Q000378:metabolism; D010957:Plasmids / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D011994:Recombinant Proteins / Q000737:chemistry; D012756:Sheep; D014162:Transfection
C525901:BMP15 protein, human; C525904:Bmp15 protein, rat; D055430:Bone Morphogenetic Protein 15; C525897:GDF9 protein, human; C525899:Gdf9 protein, rat; D055429:Growth Differentiation Factor 9; D036341:Intercellular Signaling Peptides and Proteins; D011994:Recombinant Proteins