title: The virus-associated human immunodeficiency virus type 1 Gag-Pol carrying an active protease domain in the matrix region is severely defective both in autoprocessing and in trans processing of gag particles.
mesh_terms: D020134:Catalytic Domain / Q000235:genetics; D045744:Cell Line, Tumor; D015685:Fusion Proteins, gag-pol / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D015683:Gene Products, gag / Q000235:genetics; D016333:HIV Protease / Q000737:chemistry / Q000235:genetics*; D015497:HIV-1 / Q000235:genetics / Q000502:physiology*; D006801:Humans; D011498:Protein Precursors / Q000235:genetics; D012194:RNA-Directed DNA Polymerase / Q000502:physiology; D011995:Recombination, Genetic; D019065:Virus Assembly
chemical_list: D015685:Fusion Proteins, gag-pol; D015683:Gene Products, gag; D011498:Protein Precursors; C059767:p55 gag precursor protein, Human immunodeficiency virus 1; D012194:RNA-Directed DNA Polymerase; D016333:HIV Protease