Modulating Toll-like receptor mediated signaling by (1-->3)-beta-D-glucan rapidly induces cardioprotection.
D000818:Animals; D017209:Apoptosis; D002316:Cardiotonic Agents / Q000627:therapeutic use*; D005936:Glucans / Q000627:therapeutic use*; D008297:Male; D008562:Membrane Glycoproteins / Q000378:metabolism*; D017202:Myocardial Ischemia / Q000188:drug therapy* / Q000473:pathology; D009206:Myocardium / Q000378:metabolism / Q000473:pathology; D016328:NF-kappa B / Q000378:metabolism*; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D011956:Receptors, Cell Surface / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects*; D051197:Toll-Like Receptor 4; D051193:Toll-Like Receptors; D047071:beta-Glucans
D002316:Cardiotonic Agents; D005936:Glucans; D008562:Membrane Glycoproteins; D016328:NF-kappa B; D011956:Receptors, Cell Surface; C495347:Tlr4 protein, rat; D051197:Toll-Like Receptor 4; D051193:Toll-Like Receptors; D047071:beta-Glucans; C033363:beta-1,3-glucan; D019869:Phosphatidylinositol 3-Kinases