Mutations in the extracellular loop of alpha-rENaC alter sensitivity to amiloride and reactive species.
D000584:Amiloride / Q000494:pharmacology*; D000818:Animals; D004232:Diuretics / Q000494:pharmacology*; D053503:Epithelial Sodium Channels; D008981:Molsidomine / Q000031:analogs & derivatives / Q000378:metabolism; D009154:Mutation / Q000502:physiology*; D009865:Oocytes / Q000378:metabolism; D018408:Patch-Clamp Techniques; D030421:Peroxynitrous Acid / Q000378:metabolism; D012333:RNA, Messenger / Q000096:biosynthesis; D017382:Reactive Oxygen Species / Q000378:metabolism*; D015222:Sodium Channels / Q000235:genetics*; D014982:Xenopus laevis
D004232:Diuretics; D053503:Epithelial Sodium Channels; D012333:RNA, Messenger; D017382:Reactive Oxygen Species; D015222:Sodium Channels; D030421:Peroxynitrous Acid; C002385:linsidomine; D000584:Amiloride; D008981:Molsidomine