The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis.
D000818:Animals; D015139:Blotting, Southern; D001853:Bone Marrow; D016723:Bone Remodeling / Q000502:physiology*; D001862:Bone Resorption; D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism*; D002452:Cell Count; D002478:Cells, Cultured; D024202:Electrophoretic Mobility Shift Assay; D004622:Embryo, Mammalian; D004797:Enzyme-Linked Immunosorbent Assay; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism; D015870:Gene Expression / Q000502:physiology; D006023:Glycoproteins / Q000235:genetics / Q000502:physiology*; D006416:Hematoxylin / Q000378:metabolism; D051550:I-kappa B Kinase; D017874:Immediate-Early Proteins / Q000235:genetics / Q000378:metabolism*; D015151:Immunoblotting; D015850:Interleukin-6 / Q000097:blood; D016173:Macrophage Colony-Stimulating Factor / Q000494:pharmacology; D008264:Macrophages / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D016328:NF-kappa B / Q000378:metabolism; D010010:Osteoclasts / Q000378:metabolism; D010012:Osteogenesis / Q000502:physiology*; D053244:Osteoprotegerin; D044162:Parathyroid Hormone-Related Protein / Q000378:metabolism; D011233:Precipitin Tests; D011493:Protein Kinase C / Q000235:genetics / Q000378:metabolism*; D051744:Protein Kinase C-epsilon; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D018160:Receptors, Cytoplasmic and Nuclear / Q000235:genetics / Q000502:physiology*; D018124:Receptors, Tumor Necrosis Factor; D048029:TNF Receptor-Associated Factor 6; D013997:Time Factors; D051758:Transcription Factor TFIIH; D014157:Transcription Factors
D002352:Carrier Proteins; D006023:Glycoproteins; C490981:Gtf2h1 protein, mouse; D017874:Immediate-Early Proteins; D015850:Interleukin-6; D016328:NF-kappa B; D053244:Osteoprotegerin; D044162:Parathyroid Hormone-Related Protein; D011506:Proteins; D018160:Receptors, Cytoplasmic and Nuclear; D018124:Receptors, Tumor Necrosis Factor; D048029:TNF Receptor-Associated Factor 6; C506031:Tnfrsf11b protein, mouse; D014157:Transcription Factors; D051758:Transcription Factor TFIIH; D016173:Macrophage Colony-Stimulating Factor; C497256:Prkce protein, mouse; D017346:Protein Serine-Threonine Kinases; C496564:Chuk protein, mouse; D051550:I-kappa B Kinase; C496562:Ikbkb protein, mouse; C496566:Ikbke protein, mouse; D011493:Protein Kinase C; D051744:Protein Kinase C-epsilon; D006416:Hematoxylin