title: Gab1 contributes to cytoskeletal reorganization and chemotaxis in response to platelet-derived growth factor.
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D000077214:Becaplermin; D015153:Blotting, Western; D019556:COS Cells; D002478:Cells, Cultured; D002633:Chemotaxis; D003599:Cytoskeleton / Q000737:chemistry* / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004789:Enzyme Activation; D005347:Fibroblasts / Q000378:metabolism; D005786:Gene Expression Regulation; D005799:Genes, Dominant; D005982:Glutathione Transferase / Q000378:metabolism; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D051379:Mice; D008856:Microscopy, Fluorescence; D009596:Nitrophenols / Q000737:chemistry; D009943:Organophosphorus Compounds / Q000737:chemistry; D010750:Phosphoproteins / Q000502:physiology*; D010766:Phosphorylation; D010982:Platelet-Derived Growth Factor / Q000737:chemistry* / Q000378:metabolism; D011233:Precipitin Tests; D011485:Protein Binding; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; D017027:Protein Tyrosine Phosphatases / Q000378:metabolism; D020574:Proto-Oncogene Proteins c-sis; D020797:Receptor, Platelet-Derived Growth Factor beta / Q000378:metabolism; D050796:STAT3 Transcription Factor; D015398:Signal Transduction; D013552:Swine; D013997:Time Factors; D015534:Trans-Activators / Q000378:metabolism; D014162:Transfection
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D004268:DNA-Binding Proteins; C098587:GAB1 protein, human; C490897:Gab1 protein, mouse; D047908:Intracellular Signaling Peptides and Proteins; D009596:Nitrophenols; D009943:Organophosphorus Compounds; D010750:Phosphoproteins; D010982:Platelet-Derived Growth Factor; D020574:Proto-Oncogene Proteins c-sis; D050796:STAT3 Transcription Factor; C494086:STAT3 protein, human; C494087:Stat3 protein, mouse; D015534:Trans-Activators; D000077214:Becaplermin; C008644:nitrophenylphosphate; D005982:Glutathione Transferase; D020797:Receptor, Platelet-Derived Growth Factor beta; C516724:PTPN11 protein, human; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; D017027:Protein Tyrosine Phosphatases; C516725:Ptpn11 protein, mouse