PKC activates BKCa channels in rat pulmonary arterial smooth muscle via cGMP-dependent protein kinase.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D002273:Carcinogens / Q000494:pharmacology; D017869:Cyclic GMP-Dependent Protein Kinases / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D007527:Isoenzymes / Q000037:antagonists & inhibitors / Q000378:metabolism*; D051036:Large-Conductance Calcium-Activated Potassium Channels; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000378:metabolism*; D018408:Patch-Clamp Techniques; D010703:Phorbol Esters / Q000494:pharmacology; D024681:Potassium Channels, Calcium-Activated / Q000378:metabolism*; D011493:Protein Kinase C / Q000037:antagonists & inhibitors / Q000378:metabolism*; D011651:Pulmonary Artery / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013755:Tetradecanoylphorbol Acetate / Q000031:analogs & derivatives* / Q000494:pharmacology; D014661:Vasoconstriction / Q000187:drug effects / Q000502:physiology
D002273:Carcinogens; D004791:Enzyme Inhibitors; D007527:Isoenzymes; D051036:Large-Conductance Calcium-Activated Potassium Channels; D010703:Phorbol Esters; D024681:Potassium Channels, Calcium-Activated; C016658:phorbolol myristate acetate; C080287:thymeleatoxin; D017869:Cyclic GMP-Dependent Protein Kinases; D011493:Protein Kinase C; D013755:Tetradecanoylphorbol Acetate; D002118:Calcium