Neuronal gelsolin prevents apoptosis by enhancing actin depolymerization.
D008841:Actin Cytoskeleton / Q000378:metabolism*; D000818:Animals; D017209:Apoptosis / Q000187:drug effects / Q000502:physiology*; D001388:Aziridines / Q000494:pharmacology; D015220:Calcium Channels / Q000187:drug effects / Q000378:metabolism; D020013:Calcium Signaling / Q000187:drug effects / Q000502:physiology; D053148:Caspase 3; D020169:Caspases / Q000187:drug effects / Q000378:metabolism; D002478:Cells, Cultured; D002794:Choline / Q000031:analogs & derivatives* / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005260:Female; D005333:Fetus; D018260:Gelsolin / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D008297:Male; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D051379:Mice; D018345:Mice, Knockout; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism; D009410:Nerve Degeneration / Q000378:metabolism* / Q000503:physiopathology; D009474:Neurons / Q000187:drug effects / Q000378:metabolism*; D009498:Neurotoxins / Q000494:pharmacology; D011108:Polymers / Q000378:metabolism
D001388:Aziridines; D015220:Calcium Channels; D004791:Enzyme Inhibitors; D018260:Gelsolin; D009498:Neurotoxins; D011108:Polymers; C044894:ethylcholine aziridinium; C505409:Casp3 protein, mouse; D053148:Caspase 3; D020169:Caspases; D002794:Choline