title: Patent foramen ovale and recurrent stroke: closure is the best option: no.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006348:Cardiac Surgical Procedures / Q000009:adverse effects; D015984:Causality; D002986:Clinical Trials as Topic / Q000592:standards; D015897:Comorbidity; D006344:Heart Septal Defects, Atrial / Q000453:epidemiology / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D012306:Risk; D055502:Secondary Prevention; D020521:Stroke / Q000453:epidemiology / Q000517:prevention & control*; D016896:Treatment Outcome