A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway.
D000818:Animals; D000831:Animals, Newborn; D019703:Calcineurin / Q000502:physiology*; D065095:Calcineurin Inhibitors; D006332:Cardiomegaly / Q000235:genetics*; D002460:Cell Line; D002478:Cells, Cultured; D004268:DNA-Binding Proteins; D005786:Gene Expression Regulation / Q000235:genetics*; D006321:Heart / Q000502:physiology*; D047908:Intracellular Signaling Peptides and Proteins; D008954:Models, Biological; D009124:Muscle Proteins / Q000235:genetics*; D020411:Oligonucleotide Array Sequence Analysis; D051381:Rats; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012701:Serotonin / Q000494:pharmacology; D015398:Signal Transduction; D014158:Transcription, Genetic; D014162:Transfection
D065095:Calcineurin Inhibitors; D004268:DNA-Binding Proteins; D047908:Intracellular Signaling Peptides and Proteins; D009124:Muscle Proteins; C108612:RCAN1 protein, human; D012701:Serotonin; D019703:Calcineurin