title: Rhythmic ryanodine receptor Ca2+ releases during diastolic depolarization of sinoatrial pacemaker cells do not require membrane depolarization.
mesh_terms: D000200:Action Potentials; D000818:Animals; D020013:Calcium Signaling / Q000502:physiology*; D002463:Cell Membrane Permeability / Q000187:drug effects; D003198:Computer Simulation; D003971:Diastole / Q000502:physiology*; D018613:Microscopy, Confocal; D008955:Models, Cardiovascular; D009124:Muscle Proteins / Q000502:physiology*; D009200:Myocardial Contraction / Q000502:physiology*; D010507:Periodicity; D011817:Rabbits; D019837:Ryanodine Receptor Calcium Release Channel / Q000502:physiology*; D012503:Saponins / Q000494:pharmacology; D012508:Sarcolemma / Q000502:physiology; D012849:Sinoatrial Node / Q000502:physiology*
chemical_list: D009124:Muscle Proteins; D019837:Ryanodine Receptor Calcium Release Channel; D012503:Saponins