Arginase induction promotes Trypanosoma cruzi intracellular replication in Cruzipain-treated J774 cells through the activation of multiple signaling pathways.
D000818:Animals; D001119:Arginase / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D001120:Arginine / Q000031:analogs & derivatives* / Q000494:pharmacology; D002227:Carbazoles / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects*; D017868:Cyclic AMP-Dependent Protein Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism; D003546:Cysteine Endopeptidases / Q000494:pharmacology; D004790:Enzyme Induction / Q000502:physiology*; D019833:Genistein / Q000494:pharmacology; D006131:Growth Inhibitors / Q000494:pharmacology; D007093:Imidazoles / Q000494:pharmacology; D007211:Indoles / Q000494:pharmacology; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism; D015800:Protozoan Proteins; D011725:Pyridines / Q000494:pharmacology; D011758:Pyrroles / Q000494:pharmacology; D015398:Signal Transduction / Q000187:drug effects; D014349:Trypanosoma cruzi / Q000187:drug effects / Q000201:enzymology* / Q000254:growth & development; D048051:p38 Mitogen-Activated Protein Kinases
D002227:Carbazoles; D006131:Growth Inhibitors; D007093:Imidazoles; D007211:Indoles; D015800:Protozoan Proteins; D011725:Pyridines; D011758:Pyrroles; C068309:N(omega)-hydroxyarginine; C057416:KT 5720; D001120:Arginine; D019833:Genistein; D011505:Protein-Tyrosine Kinases; D017868:Cyclic AMP-Dependent Protein Kinases; D020928:Mitogen-Activated Protein Kinases; D048051:p38 Mitogen-Activated Protein Kinases; D003546:Cysteine Endopeptidases; C063214:cruzipain; D001119:Arginase; C093642:SB 203580