Mechanisms of gastroprotection by lansoprazole pretreatment against experimentally induced injury in rats: role of mucosal oxidative damage and sulfhydryl compounds.
D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000818:Animals; D000897:Anti-Ulcer Agents / Q000494:pharmacology*; D051545:Cyclooxygenase 1; D051546:Cyclooxygenase 2; D015237:Dinoprost / Q000031:analogs & derivatives* / Q000378:metabolism; D000431:Ethanol / Q000008:administration & dosage; D005750:Gastric Juice / Q000378:metabolism; D005753:Gastric Mucosa / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism / Q000473:pathology; D006851:Hydrochloric Acid / Q000008:administration & dosage; D007527:Isoenzymes / Q000378:metabolism; D064747:Lansoprazole; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D008565:Membrane Proteins; D009336:Necrosis; D009853:Omeprazole / Q000031:analogs & derivatives* / Q000494:pharmacology*; D018384:Oxidative Stress / Q000187:drug effects*; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013276:Stomach Ulcer / Q000517:prevention & control; D013438:Sulfhydryl Compounds / Q000378:metabolism*
D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000897:Anti-Ulcer Agents; D007527:Isoenzymes; D008565:Membrane Proteins; D013438:Sulfhydryl Compounds; D064747:Lansoprazole; C075750:8-epi-prostaglandin F2alpha; D000431:Ethanol; D008315:Malondialdehyde; D015237:Dinoprost; D051545:Cyclooxygenase 1; D051546:Cyclooxygenase 2; D011451:Prostaglandin-Endoperoxide Synthases; C496513:Ptgs1 protein, rat; D009853:Omeprazole; D006851:Hydrochloric Acid