Some pyridazinone and phthalazinone derivatives and their vasodilator activities.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D001795:Blood Pressure Determination / Q000295:instrumentation / Q000379:methods; D002339:Carotid Arteries / Q000166:cytology / Q000187:drug effects; D003000:Clonidine / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005260:Female; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology; D010793:Phthalazines / Q000008:administration & dosage* / Q000138:chemical synthesis* / Q000737:chemistry; D011189:Potassium Chloride / Q000037:antagonists & inhibitors / Q000494:pharmacology; D011724:Pyridazines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats; D012756:Sheep; D014661:Vasoconstriction / Q000187:drug effects; D014664:Vasodilation / Q000502:physiology*; D014665:Vasodilator Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*
D007093:Imidazoles; D010793:Phthalazines; D011724:Pyridazines; D014665:Vasodilator Agents; D011189:Potassium Chloride; D003000:Clonidine