Activation of aPKC is required for vanadate-induced phosphorylation of protein kinase B (Akt), but not p70S6k in mouse epidermal JB6 cells.
D000818:Animals; D002460:Cell Line; D004789:Enzyme Activation / Q000187:drug effects; D004817:Epidermis / Q000201:enzymology; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects; D051379:Mice; D010766:Phosphorylation / Q000187:drug effects; D011493:Protein Kinase C / Q000235:genetics / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D011518:Proto-Oncogene Proteins / Q000378:metabolism*; D051057:Proto-Oncogene Proteins c-akt; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism; D038762:Ribosomal Protein S6 Kinases, 70-kDa / Q000378:metabolism*; D014638:Vanadates / Q000494:pharmacology*
D011518:Proto-Oncogene Proteins; D011994:Recombinant Proteins; D014638:Vanadates; D017346:Protein Serine-Threonine Kinases; D051057:Proto-Oncogene Proteins c-akt; D038762:Ribosomal Protein S6 Kinases, 70-kDa; C115015:PKC-3 protein; D011493:Protein Kinase C