Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation.
D000818:Animals; D000924:Anticholesteremic Agents / Q000494:pharmacology; D000069059:Atorvastatin; D002465:Cell Movement / Q000187:drug effects / Q000235:genetics / Q000502:physiology*; D054377:Chemokine CXCL12; D019743:Chemokines, CXC / Q000378:metabolism; D004224:Diterpenes / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D004625:Embryo, Nonmammalian / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005204:Farnesol / Q000494:pharmacology; D005854:Germ Cells / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D006538:Heptanoic Acids / Q000494:pharmacology; D006903:Hydroxymethylglutaryl CoA Reductases / Q000235:genetics / Q000502:physiology*; D008798:Mevalonic Acid / Q000494:pharmacology; D008845:Microinjections / Q000379:methods; D009025:Morpholines / Q000494:pharmacology; D017368:Protein Prenylation / Q000502:physiology*; D011758:Pyrroles / Q000494:pharmacology; D012333:RNA, Messenger / Q000378:metabolism; D016601:RNA-Binding Proteins; D019170:Somites / Q000187:drug effects; D013997:Time Factors; D015027:Zebrafish; D029961:Zebrafish Proteins / Q000378:metabolism; D005723:gamma-Glutamyltransferase / Q000378:metabolism
D000924:Anticholesteremic Agents; D054377:Chemokine CXCL12; D019743:Chemokines, CXC; D004224:Diterpenes; D004791:Enzyme Inhibitors; D006538:Heptanoic Acids; D009025:Morpholines; D011758:Pyrroles; D012333:RNA, Messenger; D016601:RNA-Binding Proteins; D029961:Zebrafish Proteins; C440015:nanos3 protein, zebrafish; D005204:Farnesol; D000069059:Atorvastatin; C017338:geranylgeraniol; D006903:Hydroxymethylglutaryl CoA Reductases; C069812:gamma-glutamyltransferase related enzyme; D005723:gamma-Glutamyltransferase; D008798:Mevalonic Acid