Tumor suppressor von Hippel-Lindau (VHL) stabilization of Jade-1 protein occurs through plant homeodomains and is VHL mutation dependent.
D000595:Amino Acid Sequence; D002460:Cell Line; D018398:Homeodomain Proteins / Q000737:chemistry*; D006801:Humans; D007680:Kidney Neoplasms / Q000209:etiology; D008969:Molecular Sequence Data; D009154:Mutation; D025521:Tumor Suppressor Proteins / Q000235:genetics / Q000502:physiology*; D044767:Ubiquitin-Protein Ligases / Q000235:genetics / Q000502:physiology*; D051794:Von Hippel-Lindau Tumor Suppressor Protein; D016335:Zinc Fingers
D018398:Homeodomain Proteins; C469360:JADE1 protein, human; D025521:Tumor Suppressor Proteins; D044767:Ubiquitin-Protein Ligases; D051794:Von Hippel-Lindau Tumor Suppressor Protein; C497446:VHL protein, human