Argininosuccinate synthase expression is required to maintain nitric oxide production and cell viability in aortic endothelial cells.
D000818:Animals; D001011:Aorta; D017209:Apoptosis; D001120:Arginine / Q000378:metabolism; D001124:Argininosuccinate Synthase / Q000096:biosynthesis / Q000502:physiology*; D002417:Cattle; D002470:Cell Survival; D002956:Citrulline / Q000378:metabolism; D004730:Endothelium, Vascular / Q000166:cytology*; D020868:Gene Silencing; D009569:Nitric Oxide / Q000096:biosynthesis*; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000032:analysis; D034741:RNA, Small Interfering / Q000494:pharmacology
D019253:Proto-Oncogene Proteins c-bcl-2; D034741:RNA, Small Interfering; D002956:Citrulline; D009569:Nitric Oxide; D001120:Arginine; D001124:Argininosuccinate Synthase