Physiological oxidants induce apoptosis and cell cycle arrest in a multidrug-resistant natural killer cell line, NK-YS.
D017209:Apoptosis; D015153:Blotting, Western; D020169:Caspases / Q000378:metabolism; D002453:Cell Cycle / Q000187:drug effects; D016923:Cell Death; D002455:Cell Division; D045744:Cell Line, Tumor; D002470:Cell Survival; D002700:Chloramines / Q000494:pharmacology; D004247:DNA / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D018432:Drug Resistance, Multiple; D019008:Drug Resistance, Neoplasm; D004789:Enzyme Activation; D006801:Humans; D006861:Hydrogen Peroxide / Q000494:pharmacology; D007376:Interleukin-2 / Q000378:metabolism; D007694:Killer Cells, Natural / Q000166:cytology*; D016877:Oxidants / Q000378:metabolism / Q000494:pharmacology*; D010766:Phosphorylation; D015375:Receptors, Interleukin-2 / Q000096:biosynthesis; D011994:Recombinant Proteins / Q000737:chemistry; D016160:Retinoblastoma Protein / Q000378:metabolism; D012694:Serine / Q000737:chemistry; D015398:Signal Transduction; D012973:Sodium Hypochlorite / Q000494:pharmacology; D013997:Time Factors; D014443:Tyrosine / Q000378:metabolism
D002700:Chloramines; D007376:Interleukin-2; D016877:Oxidants; D015375:Receptors, Interleukin-2; D011994:Recombinant Proteins; D016160:Retinoblastoma Protein; D014443:Tyrosine; D012694:Serine; D004247:DNA; D006861:Hydrogen Peroxide; D012973:Sodium Hypochlorite; D020169:Caspases; C030816:chloramine