Susceptibility pattern and molecular type of species-specific Candida in oropharyngeal lesions of Indian human immunodeficiency virus-positive patients.
A study of oropharyngeal candidiasis (OPC) in Indian human immunodeficiency virus (HIV)/AIDS patients was conducted over a period of 15 months. This study revealed that 75% of the HIV/AIDS patients had OPC. MIC testing revealed that 5% of the Candida isolates were fluconazole resistant. A correlation between CD4(+)-T-cell counts and development of OPC in HIV/AIDS patients was also observed. Molecular typing of C. albicans isolates showed that all were genetically unrelated.
School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
Ali Abdul
AA
Lattif
Uma
U
Banerjee
Rajendra
R
Prasad
Ashutosh
A
Biswas
Naveet
N
Wig
Neeraj
N
Sharma
Absarul
A
Haque
Nivedita
N
Gupta
Najma Z
NZ
Baquer
Gauranga
G
Mukhopadhyay
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D018791:CD4 Lymphocyte Count; D002175:Candida / Q000187:drug effects* / Q000302:isolation & purification*; D002180:Candidiasis, Oral / Q000175:diagnosis* / Q000276:immunology; D016172:DNA Fingerprinting; D004271:DNA, Fungal / Q000235:genetics / Q000302:isolation & purification; D025141:Drug Resistance, Fungal; D015725:Fluconazole / Q000494:pharmacology; D006679:HIV Seropositivity / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests
D004271:DNA, Fungal; D015725:Fluconazole