[Homologous vein transplantation in cruropedal arterial reconstruction].
Allogenic venous transplantation represents an alternative procedure for preventing leg amputation. This study reviewed the question of whether immunologic monitoring and immunosuppressive therapy provide results close to those of autologous reconstructions. Twenty-eight patients received 31 homologous venous transplants. The average age in this group of 15 women and 13 men was 64.5 years. Limbs in danger of amputation could be kept longer in two thirds of them. These promising results show the superiority of this method over the use of alloplastic material in regions with cruropedal vessels. Therefore, it can be recommended in acute leg ischemia with lack of autologous vascularity. Improving guidelines for indication will be an interesting research field, and more contributions are needed.
Klinik für Gefässchirurgie und Nierentransplantation, Universitätsklinikum Düsseldorf. luther@med.uni-duesseldorf.de
B
B
Luther
K M
KM
Balzer
P
P
Reinecke
R
R
Wassmuth
W
W
Sandmann
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D001157:Arterial Occlusive Diseases / Q000601:surgery*; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D005528:Foot / Q000098:blood supply*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007511:Ischemia / Q000601:surgery*; D023821:Limb Salvage; D008297:Male; D008875:Middle Aged; D014184:Transplantation, Homologous; D014680:Veins / Q000637:transplantation*
D007166:Immunosuppressive Agents