Determining variables for repeat prostate biopsy.
During the evaluation of prostate cancer, men who have undergone transrectal ultrasound-guided biopsy with negative results present a dilemma as to what further follow-up is required. Multiple variables have been proposed throughout the literature to improve cancer detection rates not only in initial biopsy results, but also on repeat evaluation. These variables include prostate-specific antigen (PSA) velocity, PSA density, free-percent PSA, and histological findings, each of which may singly or collectively dictate the need for further biopsy. After performing a Medline literature search using specific Medical Subject Headings (prostate biopsy, repeat prostate biopsy, PSA velocity, PSA density, free-percent PSA, prostate inflammation), we critically evaluated pertinent articles. Using this accumulated data and information, we composed an algorithm to assist in the decision process for repeat biopsy.
Busby
J E
JE
Department of Urology, University of California, Davis, Sacramento, California 95817, USA.
Evans
C P
CP
D000465:Algorithms; D001706:Biopsy / Q000379:methods; D003657:Decision Making; D006801:Humans; D007249:Inflammation; D008297:Male; D017430:Prostate-Specific Antigen / Q000032:analysis*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D012007:Rectum / Q000000981:diagnostic imaging; D013997:Time Factors; D018084:Ultrasonography, Interventional
D017430:Prostate-Specific Antigen