The contribution of MRI to the diagnosis of diffuse meningeal lesions.
We analysed MRI findings in patients in whom a diffuse abnormality of the meninges was revealed by MRI. We looked at T1 and T2-weighted spin-echo or fast spin-echo images and contrast-enhanced T1-weighted images. There were 15 patients with abnormalities on MRI, clinically suspected in ten. Four had meningoencephalitis, one meningeal and subcortical sarcoidosis nodules, four meningeal malignancies--one disseminated oligodendroglioma, one with meningeal infiltration around an adenocarcinoma, three meningeal infiltration by a haematological malignancy, and one a chronic subdural haematoma without a history of injury. We excluded patients with primary meningeal tumours and typical injury-related meningeal bleeding. The relatively small number of patients is due to both the infrequency of diffuse meningeal disease and to the low frequency of suspected meningeal pathology as an indication for MRI. The latter's diagnostic contribution is greatest in infectious disease and neoplastic infiltration, and less obvious in haematological malignancies. Contrast-enhanced T1-weighted images are most useful.
Department of Diagnostic Radiology, Faculty Hospital Pilsen, Alej Svobody 80, 30460 Pilsen, Czech Republic. KREUZBERG@fnplzen.cz
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Kreuzberg
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Kastner
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Ferda
D000230:Adenocarcinoma / Q000175:diagnosis; D000293:Adolescent; D000328:Adult; D002493:Central Nervous System Diseases / Q000175:diagnosis*; D002675:Child, Preschool; D005260:Female; D019337:Hematologic Neoplasms / Q000175:diagnosis; D006408:Hematoma, Subdural / Q000175:diagnosis; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis; D008578:Meninges / Q000473:pathology*; D008590:Meningoencephalitis / Q000175:diagnosis; D008875:Middle Aged; D009837:Oligodendroglioma / Q000175:diagnosis; D012507:Sarcoidosis / Q000175:diagnosis