Oxidative rearrangement of imidazoles with dimethyldioxirane.
Tetrahydrobenzimidazoles, on treatment with dimethyldioxirane, rearrange to provide 5-imidazolones exclusively. These rearrangements proceed with a broad range of substrates and with good to excellent levels of diastereoselectivity. [reaction: see text]
Department of Chemistry and Biochemistry, The University of Texas at Arlington, Arlington, TX 76019, USA. lovely@uta.edu
Carl J
CJ
Lovely
Hongwang
H
Du
Yong
Y
He
H V
HV
Rasika Dias