[Effect sandostatin on functional and structural recovery of the central nervous system after clinical death].
A behavior examination set was used to reveal a decreased anxiety as well as increased locomotor and exploratory activities and changes in resuscitated animals undergoing different learning tests. A single injection of sandostatin--an analogue of regulatory peptide somatostatin--was found to improve the structural and functional recovery of the central nervous system after a 12-minute cardiac arrest.
Volkov
A V
AV
Gorenkova
N A
NA
Nazarenko
I V
IV
Avrushchenko
M Sh
MSh
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects* / Q000502:physiology; D001921:Brain / Q000187:drug effects* / Q000503:physiopathology; D016887:Cardiopulmonary Resuscitation; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology; D004195:Disease Models, Animal; D004924:Escape Reaction / Q000187:drug effects / Q000502:physiology; D006323:Heart Arrest / Q000503:physiopathology* / Q000628:therapy; D008297:Male; D018782:Maze Learning / Q000187:drug effects / Q000502:physiology; D009043:Motor Activity / Q000187:drug effects; D015282:Octreotide / Q000627:therapeutic use*; D011689:Purkinje Cells / Q000187:drug effects / Q000473:pathology; D051381:Rats
D015282:Octreotide