[Interleukin 2 receptor--the structure, function and clinical significance in malignant diseases of adults and children].
The paper summarizes the up-to-date knowledge on structure, source, biological function and clinical significance of Interleukin-2 receptor measurements in patients suffering from neoplastic diseases. The authors review the role and clinical usefulness of soluble IL-2R alpha in neoplasms' diagnostics, prognosis and treatment monitoring both in adult patients and in children.
Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii Akademii Medycznej w Gdańsku. ebien@amedec.amg.gda.pl
Ewa
E
Bień
Anna
A
Balcerska
D000328:Adult; D014408:Biomarkers, Tumor / Q000378:metabolism*; D002648:Child; D006801:Humans; D053645:Interleukin-2 Receptor alpha Subunit; D009369:Neoplasms / Q000378:metabolism*; D011379:Prognosis; D018123:Receptors, Interleukin / Q000378:metabolism*; D015375:Receptors, Interleukin-2 / Q000737:chemistry / Q000378:metabolism*
D014408:Biomarkers, Tumor; C508017:IL2RA protein, human; D053645:Interleukin-2 Receptor alpha Subunit; D018123:Receptors, Interleukin; D015375:Receptors, Interleukin-2