(Z)-3-(1-Methyl-1H-indol-3-yl)-2-(thiophen-3-yl)acrylonitrile.
The title compound, C16H12N2S, has been synthesized by base-catalyzed condensation of 1-methylindole-3-carboxaldehyde with thiophene-3-acetonitrile. The product assumes an approximately planar Z configuration. The molecule has a thienyl-ring flip disorder.
Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536, USA.
Vijayakumar N
VN
Sonar
Sean
S
Parkin
Peter A
PA
Crooks
D000181:Acrylonitrile / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry*; D000995:Antitubercular Agents / Q000737:chemistry; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D007211:Indoles / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D013237:Stereoisomerism; D013876:Thiophenes / Q000138:chemical synthesis / Q000737:chemistry*
C496846:3-(1-methyl-1H-indol-3-yl)-2-(thiophen-3-yl)acrylonitrile; D000995:Antitubercular Agents; D007211:Indoles; D013876:Thiophenes; D000181:Acrylonitrile