Angiotensin type-1 receptor blockade increases ACE 2 expression in the heart.
Carey
Robert M
RM
D000803:Angiotensin I / Q000096:biosynthesis; D047228:Angiotensin II Type 1 Receptor Blockers; D000085962:Angiotensin-Converting Enzyme 2; D000818:Animals; D002268:Carboxypeptidases / Q000096:biosynthesis* / Q000235:genetics; D015536:Down-Regulation; D004790:Enzyme Induction / Q000187:drug effects; D006321:Heart / Q000187:drug effects*; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology / Q000627:therapeutic use; D019808:Losartan / Q000494:pharmacology / Q000627:therapeutic use; D051379:Mice; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy; D009206:Myocardium / Q000201:enzymology*; D000068557:Olmesartan Medoxomil; D010446:Peptide Fragments / Q000096:biosynthesis; D007703:Peptidyl-Dipeptidase A; D011725:Pyridines / Q000494:pharmacology; D051381:Rats; D011917:Rats, Inbred Lew; D013777:Tetrazoles / Q000494:pharmacology / Q000627:therapeutic use
D047228:Angiotensin II Type 1 Receptor Blockers; D007093:Imidazoles; D010446:Peptide Fragments; D011725:Pyridines; D013777:Tetrazoles; C073402:PD 123319; D000068557:Olmesartan Medoxomil; D000803:Angiotensin I; D002268:Carboxypeptidases; D007703:Peptidyl-Dipeptidase A; C000705307:ACE2 protein, human; C000705328:Ace2 protein, mouse; C000705329:Ace2 protein, rat; D000085962:Angiotensin-Converting Enzyme 2; C118790:angiotensin I (1-7); D019808:Losartan