Recent insights into mammalian circadian rhythms.
This short review highlights recent progress in understanding the mammalian circadian clock. Advances in the understanding of the neuroanatomy of circadian rhythms, the molecular biology of the core clock mechanism, mechanisms of light entrainment of the circadian clock, clock synchronization among multiple tissues, and recent work on the relationship of the mouse circadian clock and cancer are discussed. This review is intended as an overview of recent research activity for the interested sleep disorders clinician or researcher.
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA. vangelder@vision.wustl.edu
Russell N
RN
Van Gelder
D000818:Animals; D002909:Chronobiology Phenomena; D002940:Circadian Rhythm / Q000502:physiology*; D006801:Humans; D008027:Light; D008322:Mammals