Myocardial viability: breath-hold 3D MR imaging of delayed hyperenhancement with variable sampling in time.
A method for visualizing myocardial infarction with a three-dimensional (3D) breath-hold gated acquisition was examined. By using variable sampling in time, whole heart coverage with a single volume acquisition was achieved in 24 heart beats. In a study of 35 patients, in whom 3D volume acquisition was compared with a two-dimensional (2D) acquisition, all regions of myocardial infarction were correctly identified at 3D examination. The mean imaging time for 12 section locations was 8.0 minutes +/- 3.0 with a 2D approach compared with 22 seconds +/- 4 with a 3D approach (P <.001). Advantages were also noted for infarct contrast-to-noise ratio: 60 +/- 37 for 3D versus 33 +/- 20 for 2D imaging (P <.001). No significant differences (P >.05) were noted at qualitative assessment of myocardial suppression, endocardial border visualization, respiratory and cardiac motion artifacts, or confidence of transmurality of the infarct.
Foo
Thomas K F
TK
Applied Science Laboratory, GE Medical Systems, Baltimore, MD, USA. thomas.foo@med.ge.com
Stanley
David W
DW
Castillo
Ernesto
E
Rochitte
Carlos E
CE
Wang
Yi
Y
Lima
João A C
JA
Bluemke
David A
DA
Wu
Katherine C
KC
D000368:Aged; D016477:Artifacts; D003287:Contrast Media / Q000008:administration & dosage / Q000493:pharmacokinetics; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis*; D009206:Myocardium / Q000473:pathology; D010865:Pilot Projects; D012680:Sensitivity and Specificity; D013997:Time Factors
D003287:Contrast Media