Interface of unloaded titanium implants in the iliac crest, fibula, and scapula: a histomorphometric and biomechanical study in the pig.
OBJECTIVE
Prefabrication of free vascularized fibular flaps is a 2-stage procedure for the reconstruction of maxillary and mandibular defects. The delay between prefabrication and flap transfer is 6 weeks and depends on biomechanical stability and osseointegration of the implants. The purpose of this animal study was to evaluate implant stability by measuring the removal torque values (RTVs) at 3, 6, and 12 weeks and to compare the results with interface strength of the bone-implant surface in the fibula, the scapula, and the iliac crest under unloaded conditions.


METHODS
ITI implants (n = 108) with a sandblasted and acid-etched surface were placed in the fibula, the scapula, and the iliac crest of 6 Yorkshire pigs. Biomechanical, histologic, and histomorphometric results were collected at 3, 6, and 12 weeks, respectively.


RESULTS
Bicortical anchored 8-mm implants in the fibula (63.7 to 101.8 Ncm) showed RTVs similar to those of monocortical anchored 12-mm implants in the scapula (62.3 to 99.7 Ncm). The RTVs of monocortical anchored 8-mm and 10-mm implants in the iliac crest (19.1 to 44.3 Ncm) and the scapula (27.2 to 55.3 Ncm) were significantly lower. The bone-to-implant contact in the fibula at 3, 6, and 12 weeks (35.2%, 44.4%, and 46.8%, respectively) was similar to that in the iliac crest (24.2%, 44.2%, and 52.5%, respectively), but significantly lower than in the scapula (63.7%, 73.8%, and 74.2%, respectively).


CONCLUSIONS
Bicortical anchorage determined implant stability in the fibula, whereas interfacial strength seemed to define stability in the scapula. The quality and type of bone determined the bone's response in terms of biomechanical press fit or biologic interface strength.
Rohner
Dennis
D
Department of Plastic Surgery, Singapore General Hospital, Singapore. dennis.rohner@hirslanden.ch
Tay
Andrew
A
Chung
Sew Meng
SM
Hutmacher
Dietmar W
DW
D000818:Animals; D001696:Biomechanical Phenomena; D016025:Bone Transplantation / Q000502:physiology*; D001842:Bone and Bones / Q000502:physiology*; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D003799:Dental Stress Analysis; D020878:Device Removal; D005260:Female; D005360:Fibula / Q000502:physiology; D007085:Ilium / Q000502:physiology; D020007:Implants, Experimental; D016348:Osseointegration / Q000502:physiology*; D012540:Scapula / Q000502:physiology; D013499:Surface Properties; D013524:Surgical Flaps / Q000502:physiology*; D013552:Swine; D019415:Torque
D015921:Dental Implants