[Pim-1 induced by hypoxia is involved in drug resistance and tumorigenesis of solid tumor cells].
Teh
Beng-gwan
BG
Hokkaido University Graduate School of Dental Medicine, Sapporo 060-8586, Japan.
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D017209:Apoptosis; D015687:Cell Hypoxia / Q000502:physiology; D045744:Cell Line, Tumor; D002945:Cisplatin / Q000494:pharmacology; D003110:Colonic Neoplasms / Q000473:pathology; D004268:DNA-Binding Proteins; D019008:Drug Resistance, Neoplasm; D051793:Hypoxia-Inducible Factor 1; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D008113:Liver Neoplasms / Q000473:pathology; D051379:Mice; D016513:Mice, SCID; D009687:Nuclear Proteins; D010100:Oxygen / Q000378:metabolism; D010190:Pancreatic Neoplasms / Q000378:metabolism / Q000473:pathology*; D017346:Protein Serine-Threonine Kinases / Q000096:biosynthesis*; D011518:Proto-Oncogene Proteins / Q000096:biosynthesis*; D051573:Proto-Oncogene Proteins c-pim-1; D014157:Transcription Factors
D000970:Antineoplastic Agents; D004268:DNA-Binding Proteins; C497443:Hif1a protein, mouse; D051793:Hypoxia-Inducible Factor 1; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D009687:Nuclear Proteins; D011518:Proto-Oncogene Proteins; D014157:Transcription Factors; C496636:Pim1 protein, mouse; D017346:Protein Serine-Threonine Kinases; D051573:Proto-Oncogene Proteins c-pim-1; D002945:Cisplatin; D010100:Oxygen