Development and cross-validation of a prediction equation for estimating resting energy expenditure in healthy African-American and European-American women.
OBJECTIVE
To develop, validate, and cross-validate a formula for predicting resting energy expenditure (REE) in African-American and European-American women.


METHODS
A cross-sectional study of REE in women. Participants were randomly assigned to one of two groups. One group served to develop and validate a new equation for predicting REE while the second was used to cross-validate the prediction equation. The accuracy of the equation was compared to several existing formulae.


METHODS
University metabolic laboratory, Memphis, TN, USA.


METHODS
Healthy, premenopausal African-American and European-American women between 18 and 39 y of age. The validation sample included 239 women (age: 28.4 y, wt: 70.7 kg, body mass index (BMI): 25.2 kg/m(2), REE: 5840 kJ/day), while the cross-validation sample consisted of 232 women (age: 27.5 y, wt: 70.7 kg, BMI: 25.2 kg/m(2), REE: 5784 kJ/day).


RESULTS
The prediction equation derived from the current sample, which included adjustments for ethnicity, was the only formula that demonstrated a high level of accuracy for predicting REE in both African-American and European-American women. The mean difference between REE predicted from the new formula and measured REE was 28 kJ/day (s.d.=668) for European-American women and 142 kJ/day (s.d.=584) for African-American women.


CONCLUSIONS
Previous equations for predicting energy needs may not be appropriate for both African-American and European-American women due to ethnic differences in REE. A new equation that makes adjustments in predicted REE based on ethnicity is recommended for determining energy needs in these groups (Predicted REE (kJ/day)=616.93-14.9 (AGE (y))+35.12 (WT (kg))+19.83 (HT (cm))-271.88 (ETHNICITY: 1=African American; 0=European American)).


BACKGROUND
Support for this study was provided by Grant #HL53261 from the National Heart, Lung, and Blood Institute.
Vander Weg
M W
MW
The University of Memphis Center for Community Health, Memphis, TN 38157, USA. mvandrwg@memphis.edu
Watson
J M
JM
Klesges
R C
RC
Eck Clemens
L H
LH
Slawson
D L
DL
McClanahan
B S
BS
D000293:Adolescent; D000328:Adult; D001741:Black or African American; D001481:Basal Metabolism / Q000502:physiology*; D044383:Black People; D001823:Body Composition; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D004734:Energy Metabolism / Q000502:physiology*; D005260:Female; D006801:Humans; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014481:United States; D044465:White People