Possible contribution of C-reactive protein within coronary plaque to increasing its own plasma levels across coronary circulation.
C-reactive protein (CRP) mRNA was detected in coronary plaque. Plasma CRP levels across the coronary circulation were increased much more in patients with unstable angina pectoris and somewhat more in those with stable angina pectoris compared with controls whose coronary arteries were angiographically normal. Thus, CRP within coronary plaque might contribute to increased plasma CRP levels across coronary circulation, particularly among patients with unstable angina pectoris.
First Department of Internal Medicine, Miyazaki Medical College, Kiyotake, Miyazaki, Japan.
Tetsunori
T
Ishikawa
Takuroh
T
Imamura
Kinta
K
Hatakeyama
Haruhiko
H
Date
Toshiro
T
Nagoshi
Riichirou
R
Kawamoto
Akihiko
A
Matsuyama
Yujiro
Y
Asada
Tanenao
T
Eto
D000368:Aged; D000789:Angina, Unstable / Q000097:blood* / Q000209:etiology / Q000601:surgery; D017225:Atherectomy, Coronary; D002097:C-Reactive Protein / Q000235:genetics / Q000378:metabolism*; D003324:Coronary Artery Disease / Q000150:complications / Q000378:metabolism* / Q000601:surgery*; D003331:Coronary Vessels / Q000378:metabolism* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012333:RNA, Messenger / Q000235:genetics
D012333:RNA, Messenger; D002097:C-Reactive Protein