Genetic analysis of chromatin remodeling using budding yeast as a model.
Novel discoveries result from genetic analyses of transcription and chromatin remodeling because these methods identify activities in an unbiased manner. By describing our genetic approaches to identify regulators of PHO5 transcription and chromatin remodeling, we hope to encourage others to apply similar strategies to their genes of interest.
Steger
David J
DJ
Howard Hughes Medical Institute, University of California, San Francisco, Department of Biochemistry and Biophysics, San Francisco, California 94143-2240, USA.
O'Shea
Erin K
EK
D002843:Chromatin / Q000235:genetics* / Q000648:ultrastructure; D042002:Chromatin Assembly and Disassembly / Q000235:genetics*; D017353:Gene Deletion; D006238:Haploidy; D008957:Models, Genetic; D009154:Mutation; D028061:Phosphate Transport Proteins / Q000235:genetics; D004718:Saccharomycetales / Q000235:genetics*
D002843:Chromatin; D028061:Phosphate Transport Proteins; C055831:phosphate permease