The role of semantic knowledge on the cognitive estimation task--evidence from Alzheimer's disease and healthy adult aging.
The current study investigated the role of semantic knowledge on the Cognitive Estimation Task (CET). In an initial experiment, the CET performance of 21 patients with frontal lobe lesions was compared with 21 healthy controls. The CET was found to be sensitive to the effects of frontal lobe lesions. In Experiment 2, 175 participants aged between 18 and 87 years performed the CET to examine the effects of healthy adult aging on the task. No significant age effects were evident. In Experiment 3, 27 patients with Alzheimer's disease (AD) were compared with 27 healthy controls on the CET. AD patients produced significantly more extreme cognitive estimates than the controls. A significant correlation was found between CET performance and performance on the General Knowledge of the World Task, a task intended to assess semantic knowledge. The hypothesis is put forward that healthy older adults are able to use their intact semantic knowledge to compensate for problem-solving deficits when generating cognitive estimates. In contrast, owing to degradation in semantic abilities, AD patients are unable to benefit from semantic knowledge and instead tend to produce bizarre cognitive estimates.
Psychology Department, University of Aberdeen, Scotland, UK.
Sergio
S
Della Sala
Sarah E
SE
MacPherson
Louise H
LH
Phillips
Leonardo
L
Sacco
Hans
H
Spinnler
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology; D000544:Alzheimer Disease / Q000150:complications / Q000503:physiopathology / Q000523:psychology*; D003071:Cognition / Q000502:physiology; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology / Q000523:psychology*; D005260:Female; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis / Q000209:etiology / Q000523:psychology; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D011237:Predictive Value of Tests; D012016:Reference Values; D015203:Reproducibility of Results; D012660:Semantics; D012680:Sensitivity and Specificity; D014705:Verbal Behavior / Q000502:physiology