Prevalence of hyperinsulinemia and clinical correlates in overweight children referred for lifestyle intervention.
Although not well documented in the literature, there is growing evidence that overweight children may develop hyperinsulinemia. Children (n=171) with a body mass index greater than the 85th percentile for age using the Centers for Disease Control and Prevention growth charts for children were recruited through primary care physician offices for a lifestyle change intervention. Laboratory measurements were obtained. About 30% of these children were identified as hyperinsulinemic, using an insulin-to-glucose ratio of > or =33% or a serum insulin > or =25 microU/mL. When compared with non-hyperinsulinemic children, there were significant differences in cardiovascular risk factors. Dietetics professionals providing medical nutrition therapy to overweight children need to be aware of dietary and physical activity recommendations for individuals with marked hyperinsulinemia.
Department of Family Medicine, Brody School of Medicine at East Carolina University, 600 Moye Boulevard, Greenville, NC 27858, USA.
Catherine S
CS
Sullivan
Janalynn
J
Beste
Doyle M
DM
Cummings
Virginia H
VH
Hester
Tate
T
Holbrook
Kathryn M
KM
Kolasa
Susan
S
Morrissey
John M
JM
Olsson
James P
JP
Gutai
D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002648:Child; D002669:Child Welfare; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006946:Hyperinsulinism / Q000150:complications / Q000453:epidemiology* / Q000517:prevention & control*; D008019:Life Style; D008297:Male; D009765:Obesity / Q000150:complications*; D015995:Prevalence; D012017:Referral and Consultation / Q000706:statistics & numerical data; D014481:United States / Q000453:epidemiology