Splenectomy in cytoreductive surgery for advanced ovarian cancer.
METHODS
To evaluate the series of advanced ovarian cancer patients who underwent splenectomy as part of their surgery, a retrospective file review of 258 ovarian cancer cases were examined.


RESULTS
There were 13 cases that underwent splenectomy. These patients constitute 5% of all and 8.8% of the advanced ovarian cancer patients. Seven cases had splenectomy as part of their initial cytoreductive surgery while 6 had surgery for recurrent disease. Splenectomy was performed to resect hilar and/or capsular involvement in 9 (69%) cases, while in 3 cases (23%) splenic injury during adjacent tumoral resection required splenectomy. One patient had splenectomy for infarcts and died after the surgery with systemic complications nonrelated to the surgery. No other serious morbidity was detected. Median survival of the patients was 34 months (1-120 months) from the initial diagnosis. Median survival was 18 months (1-78 months) after the splenectomy. Three patients were still alive with no evidence of disease 2, 5 and 6.5 years after the splenectomy.


CONCLUSIONS
Splenectomy is a feasible and safe procedure. However, it should be reserved for patients in whom optimal cytoreductive results could be achieved.
Bilgin
Tufan
T
Department Of Obstetrics and Gynecology, Faculty Of Medicine, Uludağ University, Kadin Hastaliklari ve Doğum A.D., 16059 Bursa, Turkey. tbilgin@uludag.edu.tr
Ozerkan
Kemal
K
Ozan
Hakan
H
D000328:Adult; D000368:Aged; D018293:Cystadenoma, Serous / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D013156:Splenectomy / Q000379:methods*; D016019:Survival Analysis; D016896:Treatment Outcome