Assessing residual neuromuscular blockade using acceleromyography can be deceptive in postoperative awake patients.
Postoperative awake patients may have significant residual neuromuscular block. In awake patients, the results of accelerometry are affected by extra movements to which the thumb may be subject. In this study, we evaluated the repeatability of train-of-four (TOF) ratio using acceleromyography in 253 patients recovering from anesthesia. Immediately after arrival in the postanesthesia care unit, the ulnar nerve was stimulated with TOF stimulation. The evoked response at the thumb was measured by the TOF-Watch apparatus. The current intensity was 30 mA. Two TOF stimulations were applied and recorded at 30-s intervals. A Bland-Altman test was used. The Kappa (kappa) test for clinical agreement between the two measurements was also calculated according to the presence or absence of a residual neuromuscular blockade, defined as a TOF ratio <0.9. According to the presence of a residual neuromuscular blockade, the paired TOF ratios were discordant in 61 patients (24%; 95% confidence interval, 21%-27%). The kappa test indicated a moderate agreement (k = 0.47). We demonstrated that accelerometry as used in this study is not always accurate. Two isolated acceleromyograph TOF ratios are not an accurate representation of the neuromuscular status of the patient recovering from anesthesia.


CONCLUSIONS
Clinicians should be aware that acceleromyography as used in this study does not always provide precise train-of-four ratio measurements. Two isolated acceleromyograph train-of-four ratios are not an accurate representation of the neuromuscular status of the patient recovering from anesthesia.
Department of Anesthesiology and Intensive Care, Avicenne Hospital, Bobigny, France. christophe.baillard@avc.ap-hop-paris.fr
Christophe
C
Baillard
Sylvie
S
Bourdiau
Philippe
P
Le Toumelin
Farid
F
Ait Kaci
Bruno
B
Riou
Michel
M
Cupa
C Marc
CM
Samama
D000328:Adult; D000368:Aged; D000762:Anesthesia Recovery Period; D004558:Electric Stimulation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009213:Myography / Q000379:methods*; D019148:Neuromuscular Blockade; D003473:Neuromuscular Nondepolarizing Agents; D011184:Postoperative Period; D015203:Reproducibility of Results; D014459:Ulnar Nerve / Q000502:physiology; D014851:Wakefulness
D003473:Neuromuscular Nondepolarizing Agents