Idiopathic hypertrophic pyloric stenosis in identical twins.
Idiopathic hypertrophic pyloric stenosis (IHPS) was thought to be a congenital disease traditionally, even though several published reports assumed IHPS was an acquired disease. The pathogenesis and inheritance patterns of IHPS are not fully understood. Except for the familial recurrence of IHPS, concordance of IHPS in monozygotic or dizygotic twins was also noted, but occurrence in female twins is rare. From July 1992 through June 2000, 130 patients were diagnosed with IHPS in our hospital including one pair of female twins. We present the finding in the twins and review the associated articles about the pathogenesis and inheritance patterns of IHPS.
Department of Pediatrics, Chang Gung Memorial Hospital, Chiayi, Taiwan, ROC. irishcorners@yahoo.com.tw
Ju-Bei
JB
Yen
Man-Shan
MS
Kong
Wan-Jao
WJ
Wu
Chen-Sheng
CS
Huang
Kuei-Wen
KW
Chang
D004200:Diseases in Twins; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011707:Pyloric Stenosis / Q000151:congenital*