[Report on difficulty in blood group identification due to anti-H antibody in three cases].
Anti-H antibody belongs to IgM type cold antibody, which often induces the unconformity of positive and reverse typing and leads to the difficulty in clinical blood typing. Anti-H antibody was found during identification of the counter blood group in 3 cases. The antibody was found to be active at 37 degrees C, room temperature and 4 degrees C when determined by blood group serology, and was finally analyzed to be IgM. It is suggested that not to give erythrocytes of O group unreasoningly to blood recipient of AB group during emergent moment, but instead, to give same type of blood. If there was no same type of blood during urgent events, O type erythrocytes could be employed after being matched by saline centrifuging with host side coincidence and screened by incomplete method. In this case, anti-H antibody leading to adverse-reaction in blood transfusion should be prevented.
Xiao
Rui-Qing
RQ
Department of Blood Transfusion, Southwest Hospital, The Third Military Medical University, Chongqing 400038, China.
Lin
Wu-Cun
WC
Liu
Jia
J
Jiang
Tian-Lun
TL
Chen
Han-Mei
HM
Zeng
Jie
J
Zhao
Shu-Ming
SM
D000017:ABO Blood-Group System / Q000276:immunology*; D000328:Adult; D001788:Blood Grouping and Crossmatching; D005260:Female; D006801:Humans; D007518:Isoantibodies / Q000097:blood*; D008297:Male; D008875:Middle Aged
D000017:ABO Blood-Group System; D007518:Isoantibodies