High-dose antioxidant supplementation and cataract risk.
In a recent clinical trial, supplementation with high-dose antioxidants lowered the progression of lens opacities. These results differ from those of several other larger trials, in which no benefit to high-dose antioxidant supplementation was observed. Although a large body of observational evidence suggests that supplement use is associated with lower risk for cataract, there is insufficient evidence that high-dose antioxidants slow the progression of cataracts beyond that provided by multivitamins or healthful diets.
Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, Wisconsin 53705-2397, USA.
Julie A
JA
Mares
D000975:Antioxidants / Q000627:therapeutic use*; D002386:Cataract / Q000517:prevention & control*; D019587:Dietary Supplements; D018450:Disease Progression; D004305:Dose-Response Relationship, Drug; D006801:Humans
D000975:Antioxidants