Best evidence topic report. Amiodarone or flecainide for cardioversion in acute onset atrial fibrillation.
A short cut review was carried out to establish whether amiodarone is better than flecainide at restoring sinus rhythm in patients with atrial fibrillation. Altogether 42 papers were found using the reported search, of which four presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results, and study weaknesses of these best papers are tabulated. A clinical bottom line is stated.
Department of Emergency Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.
Jon
J
Argall
Ian
I
Crawford
D000638:Amiodarone / Q000627:therapeutic use*; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000188:drug therapy*; D005260:Female; D005424:Flecainide / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged
D000889:Anti-Arrhythmia Agents; D005424:Flecainide; D000638:Amiodarone