[Histomorphometric osseointegration evaluation of hydroxyapatite-coated and non-coated implants in dogs].
OBJECTIVE
Some reports showed the benefits of dental implants coated with hydroxyapatite, while some other studies found no significant difference between HA-coated implants and non-coated implants. The present study was to examine the osseointegration of HA-coated and non-coated implants in dogs.


METHODS
Twelve implants, 6 HA-coated and 6 non-coated were placed into mandibles of six dogs after teeth extraction. Animals were sacrificed after 1, 3, 6 months, respectively. Initial healing and the bone-implant interface were histomorphometrically assessed using light microscopy.


RESULTS
All implants osseointegrated; however, the ingrowth and development of new bone tissue onto HA-coated implants surface were sooner than that of non-coated ones. The index of bone osseointegration of HA-coated implants was higher than that of non-coated ones. After 1,3,6 months the osseointegration of HA-coated implants were 71.68%, 86.81%, 90.19%; While the non-coated ones'were 53.26%, 66.16%, 68.72%. The differences of them were very significant.


CONCLUSIONS
HA-coated implants enhanced initial bone tissue ingrowth and development and thus benefited the osseointegration of implants.
Department of Dentistry, The Traditional Chinese Medical Hospital of Jiading District, Shanghai 201821, China. heyongxin@yahoo.com
Yong-xin
YX
He
Yun-feng
YF
Gu
Hai-ping
HP
Cao
Cheng-kang
CK
Chang
Da-li
DL
Mao