Image enhancement by acoustic conditioning of ultrasound contrast agents.
A novel contrast imaging technique has been developed for use with microbubble contrast agents. It employs two acoustic fields: there is an excitation field for conditioning microbubbles and an imaging field for detecting microbubbles. The maximum increases (due to microbubble conditioning) in scattered first and second harmonic signals were 14.5 and 16 dB, respectively. This technique is unique for effectively enhancing the blood-to-tissue image contrast.
Shi
William T
WT
Department of Radiology, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Forsberg
Flemming
F
Bautista
Ronald
R
Vecchio
Chris
C
Bernardi
Richard
R
Goldberg
Barry B
BB
D000418:Albumins; D003287:Contrast Media; D005290:Ferric Compounds; D005466:Fluorocarbons; D007089:Image Enhancement / Q000379:methods*; D007501:Iron; D045423:Microbubbles; D010087:Oxides; D019047:Phantoms, Imaging; D011134:Polysaccharides; D014463:Ultrasonography / Q000379:methods*
D000418:Albumins; D003287:Contrast Media; C099458:FS 069; D005290:Ferric Compounds; D005466:Fluorocarbons; D010087:Oxides; D011134:Polysaccharides; C069727:Sonazoid; C059891:SHU 508; D007501:Iron