A comparison of chromatographic separation of selected nicotinic acid derivatives by TLC and HPLC techniques.
The separations of nicotinic acid and its derivatives analyzed by adsorption and reversed phase TLC and HPLC were compared. Results were presented as the dependencies of chromatographic retention parameters of studied compounds on the volume composition [%] of mobile phases. It was shown that there exists the possibility of the separation of compounds into specified groups (adsorption TLC and HPLC) and particular substances within individual groups (reversed phase TLC).
Silesian Academy of Medicine, Faculty of Pharmacy, Department of Analytical Chemistry, 4 Jagiellońska Str., 41-200 Sosnowiec, Poland.
Alina
A
Pyka
Józef
J
Sliwiok
Anna
A
Niestrój
D002626:Chemistry, Pharmaceutical; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D002855:Chromatography, Thin Layer / Q000379:methods; D009525:Niacin / Q000032:analysis* / Q000737:chemistry; D012997:Solvents
D012997:Solvents; D009525:Niacin