[A case of carcinomatous lymphangitis of the lungs due to stomach cancer responding to TS-1].
We report a case of carcinomatous lymphangitis of the lungs due to and stomach cancer showing remarkable response to TS-1. The patient was a 51-year-old man whose chest x-ray and computed tomography (CT) revealed lymphangitis, and endoscopic examination showed stomach cancer on posterior wall of stomach body. Bone marrow metastasis was suspected because platelet count was 50/microliter, and myelocytes and metamyelocytes emerged in peripheral blood. TS-1 80 mg/day was administered orally for 28 days as 1 course. After 4 courses of TS-1, chest x-ray showed remarkable improvement, and platelet count was normalized. The patient survived for 10 months after the first visit. We suggest that TS-1 is an effective therapy for carcinomatous lymphangitis of the lungs due to stomach cancer.
Dept. of Internal Medicine, Matsuyama City Hospital.
Kazuyuki
K
Akesaka
Norihiko
N
Nakanishi
Nobuo
N
Ueda
Tomonori
T
Moritaka
Takushi
T
Kitajima
Tomoya
T
Katsuta
Keizo
K
Furuya
D000230:Adenocarcinoma / Q000150:complications / Q000556:secondary; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D018279:Carcinoma, Signet Ring Cell / Q000150:complications / Q000556:secondary; D004334:Drug Administration Schedule; D004338:Drug Combinations; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008205:Lymphangitis / Q000188:drug therapy* / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D010094:Oxonic Acid / Q000627:therapeutic use*; D011725:Pyridines / Q000627:therapeutic use*; D013274:Stomach Neoplasms / Q000150:complications* / Q000473:pathology / Q000556:secondary; D005641:Tegafur / Q000627:therapeutic use*
D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid