Functional neuroimaging of social cognition in pervasive developmental disorders: a brief review.
An emerging literature on the neuroanatomical correlates of social cognition in pervasive developmental disorders is reviewed. Studies conducted with high-functioning adults with autism or Asperger's syndrome highlight patterns of decreased activation in ventromedial prefrontal cortex, temporo-parietal junction, amygdala, and periamygdaloid cortex, along with aberrantly increased activation in primary sensory cortices. Future studies should extend these important initial results to younger and more severely affected subjects.
Di Martino
Adriana
A
New York University Child Study Center, 577 First Avenue, New York, NY 10016, USA.
Castellanos
F Xavier
FX
D000328:Adult; D001921:Brain / Q000002:abnormalities / Q000098:blood supply / Q000378:metabolism; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000523:psychology*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012938:Social Perception; D014055:Tomography, Emission-Computed