Myocardial viability: breath-hold 3D MR imaging of delayed hyperenhancement with variable sampling in time.
A method for visualizing myocardial infarction with a three-dimensional (3D) breath-hold gated acquisition was examined. By using variable sampling in time, whole heart coverage with a single volume acquisition was achieved in 24 heart beats. In a study of 35 patients, in whom 3D volume acquisition was compared with a two-dimensional (2D) acquisition, all regions of myocardial infarction were correctly identified at 3D examination. The mean imaging time for 12 section locations was 8.0 minutes +/- 3.0 with a 2D approach compared with 22 seconds +/- 4 with a 3D approach (P <.001). Advantages were also noted for infarct contrast-to-noise ratio: 60 +/- 37 for 3D versus 33 +/- 20 for 2D imaging (P <.001). No significant differences (P >.05) were noted at qualitative assessment of myocardial suppression, endocardial border visualization, respiratory and cardiac motion artifacts, or confidence of transmurality of the infarct.
Applied Science Laboratory, GE Medical Systems, Baltimore, MD, USA. thomas.foo@med.ge.com
Thomas K F
TK
Foo
David W
DW
Stanley
Ernesto
E
Castillo
Carlos E
CE
Rochitte
Yi
Y
Wang
João A C
JA
Lima
David A
DA
Bluemke
Katherine C
KC
Wu
D000368:Aged; D016477:Artifacts; D003287:Contrast Media / Q000008:administration & dosage / Q000493:pharmacokinetics; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis*; D009206:Myocardium / Q000473:pathology; D010865:Pilot Projects; D012680:Sensitivity and Specificity; D013997:Time Factors
D003287:Contrast Media