[A research on the correlation of oral mucosal patches  stria diseases and epithelial dysplasia].
OBJECTIVE
The aim of the present study was to elucidate the relationship between oral mucosal patches-stria diseases and epithelial dysplasia.


METHODS
Three hundred and six cases were studied, including one hundred and forty cases of leukoplakia, one hundred and twenty cases of lichen planus,forty four cases of discoid lupus erythematosus and two cases of erythroplakia. The incidence of epithelial dysplasia in each kind of mucosal patches stria diseases were analyzed and compared. The developing tendency of 30 cases which underwent biopsy more than two times were analyzed and observed.


RESULTS
In the common mucosal patches-stria diseases,the incidence of epithelial dysplasia in leukoplakia was 56.43%,lichen planus was 20.83%, discoid lupus erythematosus was 13.64%, erythroplakia was 100%. The incidence of epithelial dysplasia were detected significantly more often in leukoplakia and erythroplakia than in lichen planus and discoid lupus erythematosus (P<0.05).


CONCLUSIONS
Leukoplakia and erythroplakia belong to premalignant lesion,whether lichen planus belongs to premalignant lesion or not is controversial.
Department of Oral Medicine, Shanghai Second Medical University, Shanghai 200011, China.
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