Pulmonary cryptococcosis with a solitary focal ground-glass opacity on high-resolution computed tomography.
We report a 74-year-old woman with cervical cancer who developed pulmonary cryptococcosis which presented as a solitary focal ground-glass opacity (GGO) on high-resolution computed tomography (HRCT). Serial HRCT showed the progression from the GGO to a discrete solid nodule. We hypothesize that the initial GGO may correspond pathologically to partial filling of air spaces with cryptococcal organisms and inflammatory cells. To our knowledge, this is the first report of pulmonary cryptococcosis with a solitary focal GGO on HRCT in the literature.
Sato
Mitsuo
M
Department of Respiratory Disease, Yokkaichi Municipal Hospital, Yokkaichi.
Okamoto
Masakazu
M
Takagi
Yasuyuki
Y
Ikeda
Takuya
T
Niimi
Takao
T
Fukatsu
Eriko
E
Maruyama
Kunihiro
K
Nara
Yoshiharu
Y
Shimokata
Kaoru
K
Hasegawa
Yoshinori
Y
D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D003453:Cryptococcosis / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D018450:Disease Progression; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D008172:Lung Diseases, Fungal / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D020775:Thoracic Surgery, Video-Assisted; D014057:Tomography, X-Ray Computed / Q000379:methods; D002583:Uterine Cervical Neoplasms / Q000150:complications
D000935:Antifungal Agents; D015725:Fluconazole