Cerebrovascular disorders in children.
Cerebrovascular disorders are an important cause of mortality and chronic morbidity in children. International incidence rates for childhood stroke (ie, from 30 days to 18 years of age) have ranged from 1.3 to 13 per 100,000 children. Ischemic stroke is probably more common than hemorrhagic stroke in children. The clinical presentation of stroke in children varies according to age and location of the stroke. Over 100 risk factors for stroke in children have been reported, but in up to one third of cases no cause is identified. The management and prevention of stroke in children is not well studied and current recommendations are based on adult studies, nonrandomized trials, or expert opinion. Over half of children with stroke will develop lifelong cognitive or motor disability and up to one third will have a recurrent stroke. This review briefly describes the epidemiology, risk factors, evaluation, treatment, and outcome of stroke in children.
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, NIH/DHHS, Building 10, Room 5S220, 10 Center Drive, MSC 1447, Bethesda, MD 20892-1447, USA. lynchj@ninds.nih.gov
John Kylan
JK
Lynch
D000293:Adolescent; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D020300:Intracranial Hemorrhages / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D020767:Intracranial Thrombosis / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D012307:Risk Factors; D020521:Stroke / Q000453:epidemiology / Q000503:physiopathology; D016896:Treatment Outcome