Characterization of TP53 microsatellite locus among selected ethnic populations of India.
A total of 253 individuals belonging to five ethnic populations of India were analyzed for pentanucleotide microsatellite TP53. These included Konkanasthas and Marathas (from Maharashtra, western India) representing Indo-Aryan lineage and Ezhavas, Nairs and Muslims (from Kerala, southwest India) representing Indo-Dravidian lineage. To the best of our knowledge, allele frequency data at TP53 microsatellite locus exists only for German Caucasians (1,2), Northern Portuguese (3) and West African from S. Tomé e Príncipe (4); the present study is the first report on Asian populations.
Low level Radiation Studies Section, Bio-Science Group, Bhabha Atomic Research Center, Trombay, Mumbai-400 085, India.
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D000328:Adult; D016172:DNA Fingerprinting / Q000379:methods; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D007194:India; D018895:Microsatellite Repeats; D016133:Polymerase Chain Reaction