[Acute thrombotic and hemorragic complications in cancer].
Acute hemorragic and thrombotic complications in cancer are often life threatening. Hemorragic disease are frequent (10%) and sometimes revealed the cancer. In more than 50% thrombocytopenia is involved. Bleeding is related to a vessel wound in 30% of the hemorragic complications either by a tumoral diffusion or by the tumor itself. In less than 10%, the bleeding is linked to disseminated intravascular coagulation. Very rarely coagulation factor deficit is found. Thrombotic manifestations are also frequent (15% of cancer patients). Venous system are usually involved. Clinicians must be aware of these complications to favor the best treatment early as possible to prevent fatal complications.
Zini
Jean-Marc
JM
Service d'hématologie clinique, hôpital Lariboisière, 75010 Paris. jean-marc.zini@lrb.ap-hop-paris.fr
D006470:Hemorrhage / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D009369:Neoplasms / Q000150:complications*; D012307:Risk Factors; D013927:Thrombosis / Q000209:etiology* / Q000628:therapy*