Neurobiology: New connections between integrins and axon guidance.
Axon guidance molecules such as netrins, semaphorins, Slits and ephrins provide the cues required for accurate patterning of axonal projections in the nervous system. Recent reports have described multiple paradigms by which these molecules interact with integrin adhesion receptors in and outside the neuronal tissues.
Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Tetsuya
T
Nakamoto
Kristin H
KH
Kain
Mark H
MH
Ginsberg
D001369:Axons / Q000502:physiology*; D002465:Cell Movement / Q000502:physiology*; D029721:Drosophila Proteins; D036342:Ephrins / Q000378:metabolism; D016023:Integrins / Q000378:metabolism / Q000502:physiology*; D009414:Nerve Growth Factors / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000378:metabolism; D000075388:Netrin-1; D039961:Semaphorins / Q000378:metabolism* / Q000502:physiology; D025521:Tumor Suppressor Proteins
D029721:Drosophila Proteins; D036342:Ephrins; D016023:Integrins; D009414:Nerve Growth Factors; D009419:Nerve Tissue Proteins; D039961:Semaphorins; D025521:Tumor Suppressor Proteins; C066819:sli protein, Drosophila; D000075388:Netrin-1