Osteoarthritis in hemodialysis patients: relationships with bone mineral density and other clinical and laboratory parameters.
OBJECTIVE
The aim of this study was to determine the role that hemodialysis (HD) plays in radiologically assessed osteoarthritis (OA) of the hand, knee, and hip.


METHODS
Eighty patients who had been on regular HD for at least 2 years were included. Anterior-posterior radiographs of the pelvis, weight-bearing knees, and hands and wrists of each patient were examined. Bone mineral density (BMD) of spine, femur, and forearm was measured.


RESULTS
Radiologic assessment of the 80 patients' hands showed that 41 individuals had osteopenia, 12 had midphalangeal subperiosteal resorption, 11 had cystic bone lesions, eight had bone erosion, four had osteophytic lesions, and three had subchondral sclerosis. Bone erosion in the hands was significantly associated with HD duration, forearm T score, and serum parathyroid hormone level. Radiologically, OA was demonstrated in eight knee and ten hip joints. Minimum joint space in the tibiofemoral compartment correlated with body mass index, and minimum joint space in the hip correlated with age. The mean BMD measurements at all three sites studied in the HD patients were low. Only the duration of HD significantly correlated with forearm BMD.


CONCLUSIONS
Osteoarticular complications are common in HD patients.
Rheumatology Division, Baskent University Faculty of Medicine, Fevzi cakmak cad. 10.sok, Bahcelievler, Ankara, Turkey 06490. hhamide@hotmail.com
Hamide
H
Kart-Köseoglu
A E
AE
Yucel
E A
EA
Niron
H
H
Köseoglu
I
I
Isiklar
F N
FN
Ozdemir
D000328:Adult; D000368:Aged; D001175:Arthrography; D015519:Bone Density / Q000502:physiology; D001847:Bone Diseases / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000209:etiology; D001851:Bone Diseases, Metabolic / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology; D001862:Bone Resorption / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology; D001842:Bone and Bones / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007596:Joints / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000150:complications / Q000453:epidemiology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000209:etiology; D020370:Osteoarthritis, Knee / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000209:etiology; D015995:Prevalence; D006435:Renal Dialysis / Q000009:adverse effects*; D012307:Risk Factors; D014421:Turkey / Q000453:epidemiology