Porphyrin traps its terminator! Concerted and stepwise porphyrin degradation mechanisms induced by heme-oxygenase and cytochrome p450.
Sharma
Pankaz K
PK
Department of Organic Chemistry and the Lise Meitner-Minerva Center for Computational Quantum Chemistry, The Hebrew University of Jerusalem, 91904 Jerusalem, Israel.
Kevorkiants
Rouslan
R
de Visser
Sam P
SP
Kumar
Devesh
D
Shaik
Sason
S
D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D006418:Heme / Q000737:chemistry* / Q000378:metabolism; D006419:Heme Oxygenase (Decyclizing) / Q000737:chemistry / Q000378:metabolism*; D006900:Hydroxylation; D008956:Models, Chemical; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D011166:Porphyrins / Q000737:chemistry* / Q000378:metabolism; D014867:Water / Q000737:chemistry
D011166:Porphyrins; D014867:Water; D006418:Heme; D003577:Cytochrome P-450 Enzyme System; D006419:Heme Oxygenase (Decyclizing); D010100:Oxygen