[How to investigate....A darkened skin lesion during pregnancy. A difficult task for the clinician].
Cancers rarely coexist with pregnancy. Cutaneous melanoma, however, is one of the most frequently encountered neoplasms during pregnancy. Gestation may also be a period during which the aspect of some melanocytic naevi can change eventhough the tumor remains benign. Distinction between a benign and a malignant lesion may then be a dilemma. Clinical morphometry, dermoscopy, skin surface biopsy, conventional histology and immunohistochemistry are valuable means that can be used to secure maximum diagnostic confidence.
Uhoda
I
I
CHU du Sart Timan, Service de Dermatopathologie.
Piérard-Franchimont
C
C
Arrese
J E
JE
Quatresooz
P
P
Cornil
F
F
Deleixhe-Mauhin
F
F
Piérard
G E
GE
D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008545:Melanoma / Q000175:diagnosis*; D008853:Microscopy; D009508:Nevus, Pigmented / Q000175:diagnosis*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis*