Elimination of microbubbles from the extracorporeal circuit: dynamic bubble trap versus arterial filter.
BACKGROUND
Open heart surgery is associated with important risk of cerebral and peripheral organ dysfunction, attributed in part to microbubbles generated in or not eliminated from the ECC. For elimination of microbubbles, a dynamic bubble trap (DBT) was developed for the arterial line of ECCs.


METHODS
Bubble eliminating properties of an arterial filter were evaluated in four CABG patients and compared to the performance of the DBT in four patients. One patient received both devices.


RESULTS
Elimination of bubbles between 40-120 microm was significantly higher with the DBT (88% vs. 57% with arterial filter, p=0.034). Reduction of bubbles below 40 microm was equivalent in both groups. The combination of both devices was most effective (94% for bubbles >40 microm).


CONCLUSIONS
Arterial filter and DBT are equally effective in elimination of smaller gas bubbles. However, bigger bubbles possibly causing cerebral and peripheral organ damage are eliminated to a greater degree by the DBT.
Martens
S
S
Department for Thoracic and Cardiovascular Surgery, University Hospital J.W. Goethe, Frankfurt am Main, Germany. martens.herz@gmx.de
Dietrich
M
M
Pietrzyk
R
R
Graubitz
K
K
Keller
H
H
Moritz
A
A
D001026:Coronary Artery Bypass / Q000379:methods; D004618:Embolism, Air / Q000209:etiology / Q000517:prevention & control*; D005112:Extracorporeal Circulation / Q000009:adverse effects*; D005374:Filtration; D006801:Humans