Triterpenoid saponin from the bark of Guaiacum officinale L.
A new triterpenoid saponin, guaianin R (1) was isolated from the n-BuOH extract of bark of Guaiacum officinale L. It was characterized as akebonic acid-3-O-[alpha-L-rhamnopyranosyl-(1 --> 3)-beta-D-glucopyranosyl-(1 --> 3)-alpha-L-rhamnopyranosyl-(1 --> 2)-alpha-L-arabinopyranoside]-28-O-[beta-D-glucopyranosyl]-ester. The structure was established with the help of a comparative study of 1D and 2D 1H- 13C NMR methods. A number of other saponins were isolated and reported from the same species.
H.E.J. Research Institute of Chemistry, International Centre for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan. vuahmad@cyber.net.pk
Viqar Uddin
VU
Ahmad
Nikhat
N
Saba
Khalid Mohammed
KM
Khan
D032441:Guaiacum / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D024301:Plant Bark / Q000737:chemistry; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification*
D012503:Saponins; C486119:akebonic acid-3-O-(rhamnopyranosyl-1-3-glucupyranosyl-1-3-rhamnopyranosyl-1-2-arabinopyranoside)-28-O-glucopyranosyl ester