[The behavior of superoxide dismutase (SOD) in serum of cows with abomasal displacement (DA)].
After surgical reposition of displaced organs (abomasum, uterus, intestines) restoration of blood flow and oxygen supply generates oxygen radicals and other reactive oxygen species. SOD indicates radical stress of the organism. Subject of the study was the question if SOD can be detected in blood serum samples of cows and if there are differences in SOD activity between healthy cows and cows with Dislocatio abomasi (DA). We also wanted to investigate the influence of breed "Schwarzbunte" with DA (16 left/5 rights). The samples were drawn before and 1, 3 and 24 post op. Ten healthy cows of the same breed were also examined (2 weeks and 4-6 weeks after calving). There are no significant differences between the SOD activity of healthy cows and cows with DA, but the SOD activity of cows with left DA is significant lower than the activity of cows with right DA. Post op. SOD activity decreases; 24 h after surgery cows with left but not with right DA show an increase of SOD activity similar to values before surgery. There is a close positive correlation between SOD activity and protein concentration as well as negative correlation to concentration of free fatty acids after surgery. The behaviour of SOD activity shows that the surgical replacement of the displaced abomasum can generate a depression of the antioxidative capacity of the organism.
Medizinische Tierklinik, Veterinärmedizinischen Fakultät Leipzig. mfuerll@rz.uni-leipzig.de
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D000018:Abomasum / Q000002:abnormalities* / Q000601:surgery*; D000818:Animals; D001947:Breeding; D002417:Cattle / Q000097:blood*; D005260:Female; D017382:Reactive Oxygen Species; D013482:Superoxide Dismutase / Q000097:blood*
D017382:Reactive Oxygen Species; D013482:Superoxide Dismutase