Mass spectra of N-substituted cantharidinimides.
The mass spectra of a series of N-substituted cantharidinimides were examined. The feature of this series compounds is a sequential double hydrogen transfer from the oxabicycloheptane unit to either the carbonyl group of the succinimide unit or the nitrogen atom of the pyridyl or thiazolyl substituent through space. The ability of the N-substituent to accept a hydrogen atom possibly leads to the different fragmentation pathway.
School of Pharmacy, Taipei Medical University, 110 Taipei, Taiwan.
Pen-Y
PY
Lin
Shaw-T
ST
Lin
David W-M
DW
Liang
D002193:Cantharidin / Q000031:analogs & derivatives* / Q000032:analysis*; D007509:Irritants / Q000032:analysis*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*
D007509:Irritants; D002193:Cantharidin