Mössbauer spectroscopy in biomedical research.
This work discusses the main directions and results of the application of Mössbauer spectroscopy of iron containing species in biomedical research. These studies demonstrate the wide possibilities of Mössbauer spectroscopy to obtain physical parameters and information about the iron electronic structure in normal and pathological biomolecules, model compounds and pharmaceutical samples as well as about qualitative and quantitative changes of iron containing biomolecules during pathological processes or the effect of environmental factors. The results obtained may be useful for further understanding of the molecular nature of diseases and pathological processes.
Oshtrakh
Mlichael I
MI
Division of Applied Biophysics, Faculty of Physical Techniques and Devices for Quality Control, Ural State Technical University-UPI, Ekaterinburg 620002, Russian Federation. oshtrakh@mail.utnet.ru
D000328:Adult; D000465:Algorithms; D035843:Biomedical Research; D001798:Blood Proteins / Q000032:analysis; D004912:Erythrocytes / Q000737:chemistry*; D005293:Ferritins / Q000737:chemistry; D006801:Humans; D007231:Infant, Newborn; D007501:Iron / Q000097:blood / Q000378:metabolism; D007505:Iron-Dextran Complex / Q000737:chemistry; D010108:Oxyhemoglobins / Q000032:analysis*; D015204:Spectroscopy, Mossbauer
D001798:Blood Proteins; D010108:Oxyhemoglobins; D007505:Iron-Dextran Complex; D005293:Ferritins; D007501:Iron