[Acute thrombotic and hemorragic complications in cancer].
Acute hemorragic and thrombotic complications in cancer are often life threatening. Hemorragic disease are frequent (10%) and sometimes revealed the cancer. In more than 50% thrombocytopenia is involved. Bleeding is related to a vessel wound in 30% of the hemorragic complications either by a tumoral diffusion or by the tumor itself. In less than 10%, the bleeding is linked to disseminated intravascular coagulation. Very rarely coagulation factor deficit is found. Thrombotic manifestations are also frequent (15% of cancer patients). Venous system are usually involved. Clinicians must be aware of these complications to favor the best treatment early as possible to prevent fatal complications.
Service d'hématologie clinique, hôpital Lariboisière, 75010 Paris. jean-marc.zini@lrb.ap-hop-paris.fr
Jean-Marc
JM
Zini
D006470:Hemorrhage / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D009369:Neoplasms / Q000150:complications*; D012307:Risk Factors; D013927:Thrombosis / Q000209:etiology* / Q000628:therapy*