Role of afferent control in maintaining structural and metabolic characteristics of stretched soleus in rats exposed to hindlimb suspension.
It is known that gravitational unloading (GU) induces atrophy of skeletal muscles and slow-to-fast muscle fiber (MF) transformation. Stretching of m. soleus prevents those changes, probably afferent information from the stretched muscle acting as triggering mechanism. It was shown that EMG of suspended animals or of stretched muscle is similar to that of control animals. Our study was aimed at revealing contribution of the afferent information from stretched m.soleus exposed to GU in maintenance of cross-sectional area (CSA) of MF and of myosine heavy chains and oxidative potential of skeletal muscles.
Lomonosov Moscow State University, Faculty of Basic Medicine.
T L
TL
Nemirovskaya
B S
BS
Shenkman
A
A
Muchina
Y
Y
Volodkovich
M
M
Sayapina
O
O
Larina
E
E
Bratcseva