[Teutschländer disease. A rare benign differential diagnosis of proliferative space-occupying lesions in the periarticular soft tissue].
The tumoral calcinosis (synonym: Teutschländer disease) is a very rare benign metabolic dysfunction of unknown etiology. It manifests principally as massive subcutaneous soft tissue deposits of calcium phosphate near the large joints and is also characterized by slow progressive growth. Causally, a disturbance of the calcium and phosphate metabolism/balance with, among others, autosomal dominant heredity is suspected. It appears frequently in the black African population in all age groups, but preferentially in the 1st and 2nd decades of life. Medical help is most frequently sought because of increasing tumor size causing displacement and consecutive pain as well as decreased joint play. We present here a case of Teutschländer disease in a 50-year-old woman on long-term hemodialysis and describe the clinical, radiological, and pathological signs of this rare disease. Subsequently, speculative etiology, differential diagnostic considerations as well as the therapeutic interventions for tumoral calcinosis are discussed taking into consideration the current literature.
Mumme
T
T
Orthopädische Klinik, Universitätsklinikum Aachen. torsten.mumme@gmx.de
Griefingholt
H
H
Schmidt-Rohlfing
B
B
Müller-Rath
R
R
Kochs
A
A
D002114:Calcinosis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003238:Connective Tissue / Q000473:pathology / Q000601:surgery; D003560:Cysts / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D007677:Kidney Function Tests; D008875:Middle Aged; D010489:Periarthritis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006435:Renal Dialysis; D012307:Risk Factors; D012782:Shoulder / Q000473:pathology / Q000601:surgery