Levetiracetam in progressive myoclonic epilepsy: an exploratory study in 9 patients.
The authors conducted an open study of levetiracetam as add-on therapy in nine patients with well-defined progressive myoclonic epilepsies and refractory myoclonus. Myoclonus was evaluated semiquantitatively (territory, intensity, daily living activities). Five patients had improvement of their myoclonus score. Levetiracetam may benefit myoclonus in progressive myoclonic epilepsy.
Unité d'Epileptologie, Hôpital de la Pitié-Salpêtrière, Paris, France.
C
C
Crest
S
S
Dupont
E
E
Leguern
C
C
Adam
M
M
Baulac
D000203:Activities of Daily Living; D000293:Adolescent; D000927:Anticonvulsants / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D000077287:Levetiracetam; D017243:MERRF Syndrome / Q000188:drug therapy*; D008297:Male; D010889:Piracetam / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D016896:Treatment Outcome; D020194:Unverricht-Lundborg Syndrome / Q000188:drug therapy*
D000927:Anticonvulsants; D000077287:Levetiracetam; D010889:Piracetam