Role of therapeutic vaccines in the control of HIV-1.
The recent success of highly active antiretroviral therapy (HAART) has altered the prognosis of patients living with HIV-1 infection. However, there are still many challenges to be addressed if we want to develop long-term therapeutic strategies for patients, in both the Western world and resource-poor countries. In this review, the potential role for HIV-1 therapeutic vaccines in the era of HAART will be discussed in the light of the present efforts at developing immune-based therapies to complement antiviral treatment and minimize the duration of exposure to antiviral drugs.
Kinloch-de Loes
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Department of HIV/Thoracic Medicine, The Royal Free Centre for HIV Medicine, Royal Free Campus, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK. sabine@kinloch.u-net.com
D016915:AIDS Vaccines / Q000494:pharmacology* / Q000627:therapeutic use*; D000818:Animals; D015658:HIV Infections / Q000276:immunology / Q000517:prevention & control*; D015497:HIV-1 / Q000187:drug effects* / Q000276:immunology; D006801:Humans
D016915:AIDS Vaccines