Identifying transcriptional targets.
Identifying the targets of transcription factors is important for understanding cellular processes. We review how targets have previously been isolated and outline new technologies that are being developed to identify novel direct targets, including chromatin immunoprecipitation combined with microarray screening and bioinformatic approaches.
Wellcome Trust/Cancer Research UK Gurdon Institute and Department of Zoology, University of Cambridge, Cambridge CB2 1QR, UK.
Nicola V
NV
Taverner
James C
JC
Smith
Fiona C
FC
Wardle
D000818:Animals; D001665:Binding Sites / Q000235:genetics; D004247:DNA / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D014157:Transcription Factors / Q000235:genetics* / Q000378:metabolism
D014157:Transcription Factors; D004247:DNA