Rho-regulatory proteins in breast cancer cell motility and invasion.
The importance of the Rho-GTPases in cancer progression, particularly in the area of metastasis, is becoming increasingly evident. This review will provide an overview of the role of the Rho-regulatory proteins in breast cancer metastatis.
Lin
Min
M
Department of Internal Medicine, The University of Michigan Comprehensive Cancer Center, Ann Arbor, MI 48109-0948, USA.
van Golen
Kenneth L
KL
D001943:Breast Neoplasms / Q000201:enzymology / Q000473:pathology*; D002465:Cell Movement / Q000502:physiology; D005260:Female; D020690:GTPase-Activating Proteins / Q000378:metabolism; D020730:Guanine Nucleotide Dissociation Inhibitors / Q000378:metabolism; D020662:Guanine Nucleotide Exchange Factors / Q000378:metabolism; D006801:Humans; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D020741:rho GTP-Binding Proteins / Q000096:biosynthesis / Q000502:physiology*; D062947:rho-Specific Guanine Nucleotide Dissociation Inhibitors
D020690:GTPase-Activating Proteins; D020730:Guanine Nucleotide Dissociation Inhibitors; D020662:Guanine Nucleotide Exchange Factors; D062947:rho-Specific Guanine Nucleotide Dissociation Inhibitors; D020741:rho GTP-Binding Proteins