Transfer standard for beta decay radionuclides in radiotherapy.
The measurement of the activity of therapeutic radiopharmaceuticals prior to the administration to patients is normally achieved via the use of radionuclide calibrators. An accurate measurement of the activity of pure beta-emitters is complex. Calibration problems can be solved by combining a primary calibration with a 90Y reference solution and a 90Sr/90Y transfer standard with a solid source, simulating geometric effects caused by high energetic beta radiation. The recent development of a 90Sr/90Y transfer standard for this purpose is reported.
AEA Technology QSA GmbH, Gieselweg 1, Braunschweig 38110, Germany. klaus.thieme@de.aeat.com
Klaus
K
Thieme
Uwe
U
Beinlich
Eberhard
E
Fritz
D001610:Beta Particles; D002138:Calibration / Q000592:standards; D011786:Quality Control; D011868:Radioisotopes / Q000032:analysis* / Q000592:standards* / Q000627:therapeutic use; D011874:Radiometry / Q000295:instrumentation* / Q000379:methods / Q000592:standards*; D019275:Radiopharmaceuticals / Q000032:analysis / Q000592:standards / Q000627:therapeutic use; D011879:Radiotherapy Dosage / Q000592:standards*; D012015:Reference Standards; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012996:Solutions; D013048:Specimen Handling / Q000295:instrumentation* / Q000379:methods / Q000592:standards*; D013594:Syringes / Q000592:standards*; D014481:United States
D011868:Radioisotopes; D019275:Radiopharmaceuticals; D012996:Solutions