A new insecticidal protolimonoid from Aegle marmelos.
Bioassay-directed fractionation of the ethyl acetate extracts of the stem bark of Aegle marmelos Correa (Rutaceae) afforded a new compound, named skimmiarepin C, along with skimmiarepin A. The latter is a known compound but isolation from A. marmelos is new. The new compound is a senecioate ester analogue of the latter. Full identification of the new compound was achieved using spectroscopic methods on the separated mono-acetate derivatives. Skimmiarepins A and C exhibit moderate insecticidal activity against Phaedon cochleariae and Musca domestica in comparison with natural pyrethrum extract. The two epimeric acetates of skimmiarepin C are both less active.
Biological Chemistry Division, Rothamsted Research, Harpenden, Hertfordshire AL5 2JQ, UK.
J K R Radhika
JK
Samarasekera
Bhupinder P S
BP
Khambay
K Patrick
KP
Hemalal
D045471:Aegle / Q000737:chemistry*; D000818:Animals; D001681:Biological Assay; D001517:Coleoptera; D006793:Houseflies; D007306:Insecticides / Q000494:pharmacology; D036701:Limonins; D024301:Plant Bark / Q000737:chemistry; D013057:Spectrum Analysis; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D007306:Insecticides; D036701:Limonins; D014315:Triterpenes; C486120:skimmiarepin C