Staphylococcus aureus isolates with reduced susceptibility to glycopeptides belong to accessory gene regulator group I or II.
We used multiplex PCR to determine the agr group membership of 18 European glycopeptide heterointermediate and intermediate-resistant Staphylococcus aureus strains. Of the 15 agr group I strains, 13 were resistant and 2 were susceptible to methicillin. The remaining three strains, like the United States and Japanese control strains, belonged to agr group II.
Verdier
Isabelle
I
National Reference Laboratory for Staphylococci, INSERM E0230, IFR62, Faculté de Médecine Laennec, Lyon, France.
Reverdy
Marie-Elisabeth
ME
Etienne
Jerome
J
Lina
Gérard
G
Bes
Michèle
M
Vandenesch
François
F
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004591:Electrophoresis, Polyacrylamide Gel; D015964:Gene Expression Regulation, Bacterial / Q000235:genetics*; D005798:Genes, Bacterial / Q000235:genetics*; D006020:Glycopeptides / Q000494:pharmacology*; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics*
D000900:Anti-Bacterial Agents; D006020:Glycopeptides