September 2003: a 79-year-old female with right frontal lobe mass.
The September2003 COM. A 79-year-old woman with prior history of breast cancer and meningioma presented with headache, memory changes and sleep disturbance for four months. CT and MRI revealed a large cystic mass in the right frontal lobe with heterogeneity and an enhancing border. She had a craniotomy and resection of tumor. The tumor was histologically consistent with gliosarcoma. Gliosarcomas exhibit clinical features and genetic profiles similar to primary (de novo) glioblastoma. Gliosarcomas have the same as prognosis as glioblastoma multiforme.
Paueksakon
Paisit
P
Department of Pathology, Baylor College of Medicine and The Methodist Hospital, Houston, Tex, USA.
Blacklock
Jerry B
JB
Powell
Suzanne Z
SZ
Goodman
J Clay
JC
D000368:Aged; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005625:Frontal Lobe / Q000378:metabolism / Q000473:pathology*; D018316:Gliosarcoma / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008579:Meningioma / Q000473:pathology