Changes in potassium currents of vascular smooth muscle cells from hindquarter arteries of 4-wk simulated weightlessness rats.
It has been reported by Delp et al and Ma J et al that the vasoreactivity of hindquarter vessels from simulated weightless rats decreased. Many factors may contribute to the depressed vasoreactivity. Because the potassium channels play an important role in regulating the resting potential and contribute to the action of some vasoactive substances, we speculated that the changes of potassium channels may be an electro-physiological mechanism involved in the depressed vasoreactivity of hindquarter vessels due to simulated weightlessness.
Department of Aerospace Physiology, the Fourth Military Medical University, Xi'an, P.R. China.
Zhao-Jun
ZJ
Fu
Hong-Wei
HW
Cheng
Li-Fan
LF
Zhang
Jin
J
Ma