Susceptibility pattern and molecular type of species-specific Candida in oropharyngeal lesions of Indian human immunodeficiency virus-positive patients.
A study of oropharyngeal candidiasis (OPC) in Indian human immunodeficiency virus (HIV)/AIDS patients was conducted over a period of 15 months. This study revealed that 75% of the HIV/AIDS patients had OPC. MIC testing revealed that 5% of the Candida isolates were fluconazole resistant. A correlation between CD4(+)-T-cell counts and development of OPC in HIV/AIDS patients was also observed. Molecular typing of C. albicans isolates showed that all were genetically unrelated.
Lattif
Ali Abdul
AA
School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
Banerjee
Uma
U
Prasad
Rajendra
R
Biswas
Ashutosh
A
Wig
Naveet
N
Sharma
Neeraj
N
Haque
Absarul
A
Gupta
Nivedita
N
Baquer
Najma Z
NZ
Mukhopadhyay
Gauranga
G
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D018791:CD4 Lymphocyte Count; D002175:Candida / Q000187:drug effects* / Q000302:isolation & purification*; D002180:Candidiasis, Oral / Q000175:diagnosis* / Q000276:immunology; D016172:DNA Fingerprinting; D004271:DNA, Fungal / Q000235:genetics / Q000302:isolation & purification; D025141:Drug Resistance, Fungal; D015725:Fluconazole / Q000494:pharmacology; D006679:HIV Seropositivity / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests
D004271:DNA, Fungal; D015725:Fluconazole