A canine parvovirus mutant is spreading in Italy.
By antigenic and genetic characterization of canine parvovirus type 2 (CPV-2) strains collected in 2001 and 2002 in Italy, it was possible to observe the spread of viruses with an unusual mutation, Glu-426, affecting a major antigenic epitope of CPV-2. Out of 67 strains analyzed, 49 (73.13%) were characterized as CPV-2a, 6 (8.95%) were characterized as CPV-2b, and 12 (17.91%) were characterized as the Glu-426 mutant.
Martella
Vito
V
Department of Animal Health and Wellbeing, University of Bari, Bari, Italy. v.martella@veterinaria.uniba.it
Cavalli
Alessandra
A
Pratelli
Annamaria
A
Bozzo
Giancarlo
G
Camero
Michele
M
Buonavoglia
Domenico
D
Narcisi
Donato
D
Tempesta
Maria
M
Buonavoglia
Canio
C
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D002335:Carnivora; D004283:Dog Diseases / Q000821:virology*; D004285:Dogs; D005843:Geography; D006385:Hemagglutination Inhibition Tests / Q000662:veterinary; D007558:Italy / Q000453:epidemiology; D008907:Mink; D010322:Parvoviridae Infections / Q000453:epidemiology / Q000635:transmission / Q000662:veterinary*; D017992:Parvovirus / Q000302:isolation & purification*; D017993:Parvovirus, Canine / Q000302:isolation & purification*; D019596:Wolves
D000956:Antigens, Viral