Pure red cell aplasia associated with parvovirus B19 infection occurring late after allogeneic bone marrow transplantation.
Differential diagnosis for anemia late after allogeneic stem cell transplantation is broad. In this report, we describe a case of severe anemia secondary to pure red cell aplasia associated with human parvovirus B19 infection over 8 years after allogeneic bone marrow transplantation. Characteristics of parvovirus B19 infection and the immunosuppressed state after allogeneic stem cell transplantation are reviewed.
Hayes-Lattin
Brandon
B
Adult Bone Marrow Transplant Program, Division of Hematology and Medical Oncology, Oregon Health and Science University, The OHSU Cancer Institute, Portland, Oregon 97239, USA. hayeslat@ohsu.edu
Seipel
Timothy J
TJ
Gatter
Ken
K
Heinrich
Michael C
MC
Maziarz
Richard T
RT
D000740:Anemia / Q000175:diagnosis / Q000209:etiology / Q000276:immunology / Q000821:virology; D001856:Bone Marrow Examination; D016026:Bone Marrow Transplantation / Q000009:adverse effects* / Q000276:immunology; D003937:Diagnosis, Differential; D006086:Graft vs Host Disease / Q000150:complications / Q000276:immunology / Q000821:virology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010322:Parvoviridae Infections / Q000150:complications* / Q000276:immunology / Q000821:virology; D016732:Parvovirus B19, Human; D012010:Red-Cell Aplasia, Pure / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000821:virology; D014184:Transplantation, Homologous