[Multiple cerebral tuberculomas resistant to conventional therapy in an immunocompromised subject].
A 33 years old immunocompromised woman was admitted for a fever of unknown origin during the last five months. She referred a body temperature up to 38.3 degrees C, headache, weakness. The physical examination revealed right homonymous hemianopia, hyperreflexia and Babinski on her right side. A TC scan and a following bioptic specimen showed multiple cerebral tuberculomas. A conventional therapy was started but no significative improvement was observed. She was finally treated with interferon gamma and GM-CSF in addition to the therapy with an important regression of the lesions and significative improvement of the fever and neurological findings.
A
A
Picardi
F
F
Navajas
E M
EM
Zardi
S
S
Scarlata
S
S
Spoto
U
U
Vespasiani Gentilucci
L
L
De Galasso
E
E
Sgambato
S
S
Costantino
D000328:Adult; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D016862:Tuberculoma, Intracranial / Q000188:drug therapy* / Q000276:immunology