[Modern principles of the pathogenetic therapy of the burn shock].
The article is devoted to the review of main directions of anti-shock therapy improvement for patients with severe burns. It is shown that the treatment efficiency can be considerably increased both by optimization of infusion volume and by the use of modern infusion drugs with anti-hypoxic and anti-oxidant effects. The use of anti-hypoxic and anti-oxidant drugs permits to change the burn shock course and to decrease its duration. Decrease in severity of tissue hypoxia, prevention of cellular membrane injury interrupt one of the circuits of burn disease pathogenesis and create the favorable conditions for realization of acute adaptation mechanisms in terms of traumatic disease conception. The modern schemes of anti-shock therapy approved at the department of thermal injuries were used in the treatment of casualties with combined burns after the armed conflict in the territory of Chechnia (1999-2001).
Sidel'nikov
V O
VO
Batkin
A A
AA
Paramonov
B A
BA
Matveenko
A V
AV
Klimov
A G
AG
Tarasenko
M Iu
MIu
Kallistov
D B
DB
Zinov'ev
E V
EV
Admakin
A L
AL
Petrachkov
S A
SA
D000700:Analgesics / Q000008:administration & dosage / Q000627:therapeutic use*; D000975:Antioxidants / Q000008:administration & dosage / Q000627:therapeutic use*; D002056:Burns / Q000150:complications / Q000378:metabolism / Q000628:therapy*; D005440:Fluid Therapy; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D012774:Shock, Traumatic / Q000209:etiology / Q000378:metabolism / Q000628:therapy*
D000700:Analgesics; D000975:Antioxidants