Leiomyosarcoma of the maxillary sinuses: report of two cases.
Leiomyosarcoma is a malignant smooth-muscle tumor that has a predilection for the gastrointestinal tract and the female genital tract. It is locally fast-spreading and highly aggressive, and the prognosis is poor. We report two cases of leiomyosarcoma of the maxilla in patients who sought treatment for maxillary swelling, nasal obstruction, and epistaxis; one patient also had orbital involvement and cervical lymph node metastasis. Both patients underwent radical surgery followed by chemo- and/or radiotherapy. The patient with orbital involvement died shortly thereafter, but the other was disease-free at 18 months.
Prasad
Kishore Chandra
KC
Department of Otolaryngology, Kasturba Medical College, Mangalore, India. kishorecprasad@yahoo.com
Alva
Thokur Bhasker
TB
Khadilkar
Urmila
U
Madhu
Damodara
D
D000328:Adult; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis* / Q000503:physiopathology; D008198:Lymph Nodes / Q000473:pathology / Q000503:physiopathology; D008444:Maxillary Sinus Neoplasms / Q000175:diagnosis* / Q000503:physiopathology; D009362:Neoplasm Metastasis / Q000503:physiopathology; D011379:Prognosis; D018235:Smooth Muscle Tumor / Q000175:diagnosis / Q000503:physiopathology