Anterior cingulum abnormalities in male patients with schizophrenia determined through diffusion tensor imaging.
OBJECTIVE
This study used diffusion tensor imaging to examine fractional anisotropy in the anterior cingulum and posterior cingulum bundles in patients with schizophrenia.


METHODS
Twenty-one male patients and 20 healthy comparison men were studied.


RESULTS
Reduced fractional anisotropy was seen for both sides of the anterior cingulum in the schizophrenia patients, who also exhibited less left-greater-than-right asymmetry in the anterior cingulum than was seen in the comparison subjects.


CONCLUSIONS
The findings suggest structural disconnections in the anterior cingulum in patients with schizophrenia.
Institute of Mental Health, Peking University, Beijing, China.
Fei
F
Wang
Zhiguo
Z
Sun
Liwei
L
Cui
Xiangke
X
Du
Xilin
X
Wang
Hongyan
H
Zhang
Zhong
Z
Cong
Nan
N
Hong
Dai
D
Zhang
D000704:Analysis of Variance; D016880:Anisotropy; D038524:Diffusion Magnetic Resonance Imaging; D004292:Dominance, Cerebral / Q000502:physiology; D006179:Gyrus Cinguli / Q000002:abnormalities* / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D009415:Nerve Net / Q000002:abnormalities / Q000473:pathology; D012016:Reference Values; D012559:Schizophrenia / Q000175:diagnosis* / Q000503:physiopathology; D012565:Schizophrenic Psychology