[Biological activity of the isothiazole derivatives].
The isothiazole ring was first synthesized in 1956 by Adams and Slack. It was known earlier in condensed structures such as benzisothiazole (saccharin for example). The first found natural origin isothiazole derivative was brassilexin--a phytoalexin from Brassica juncea. In this review diverse biological activity of isothiazole derivatives and their application has been presented.
Instytut Immunologii i Terapii Doświadczalnej PAN im. Ludwika Hirszfelda we Wrocławiu. mbrodzki@iitd.pan.wroc.pl
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D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000977:Antiparasitic Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000998:Antiviral Agents / Q000138:chemical synthesis / Q000494:pharmacology; D013844:Thiazoles / Q000737:chemistry* / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D000970:Antineoplastic Agents; D000977:Antiparasitic Agents; D000998:Antiviral Agents; D013844:Thiazoles