EEG patterns in persons exposed to ionizing radiation as a result of the chernobyl accident. Part 2: quantitative EEG analysis in patients who had acute radiation sickness.
Cross-sectional quantitative electroencephalogram (qEEG) study (1996-2001) among Chernobyl accident survivors, who had confirmed acute radiation sickness and were irradiated in dose of 1-5 Gy, revealed the neurophysiological markers of ionizing radiation. Neuropsychological markers were: left fronto-temporal dominant frequency reduction; absolute delta-power lateralization to the left (dominant) hemisphere; relative delta-power increase in the fronto-temporal areas; absolute theta-power decrease in the left temporal region; absolute and relative alpha-power diffusive decrease, which may reflect cortico-limbic dysfunction lateralized to the left, dominant hemisphere, with the fronto-temporal cortical and hippocampal damage. Quantitative electroencephalogram proposed for differentiation of radiation and nonradiation brain damages and as a new biological dosymetry method. High radiosensitivity of the brain, neocortex, and dominant hemisphere higher radiosensitivity are discussed.
Department of Radiation Psychoneurology, Instiute of Clinical Radiology, Scientific Center for Radiation Medicine of Academy of Medical Sciences of Ukraine, Kiev. logan@rcrm.kiev.ua
Konstantin N
KN
Loganovsky
Konstantin L
KL
Yuryev
D001931:Brain Mapping; D002540:Cerebral Cortex / Q000002:abnormalities / Q000503:physiopathology / Q000528:radiation effects*; D003430:Cross-Sectional Studies; D004307:Dose-Response Relationship, Radiation; D004569:Electroencephalography; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D011832:Radiation Injuries / Q000453:epidemiology / Q000503:physiopathology*; D011839:Radiation, Ionizing; D018788:Radioactive Hazard Release; D012426:Russia