Prognostic value of neopterin levels in treated patients with hypertension and chest pain but without obstructive coronary artery disease.
We sought to assess the relation between circulating levels of inflammation markers, such as neopterin and C-reactive protein, and the development of adverse cardiovascular events in patients with hypertension but without obstructive coronary artery disease. We observed that patients who developed adverse events during follow-up had significantly higher neopterin levels compared with patients without events.
Coronary Artery Disease Research Unit, Department of Cardiological Sciences, St. George's Hospital Medical School, London, United Kingdom.
Pablo
P
Avanzas
Ramón
R
Arroyo-Espliguero
Juan
J
Cosin-Sales
Juan
J
Quiles
Emmanouil
E
Zouridakis
Juan Carlos
JC
Kaski
D000368:Aged; D000787:Angina Pectoris / Q000097:blood* / Q000150:complications; D002097:C-Reactive Protein / Q000378:metabolism*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000150:complications; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology; D019798:Neopterin / Q000097:blood*; D011237:Predictive Value of Tests; D011379:Prognosis; D015203:Reproducibility of Results; D012307:Risk Factors; D012720:Severity of Illness Index
D019798:Neopterin; D002097:C-Reactive Protein