A pilot trial of quetiapine for the treatment of patients with delirium.
Twenty-two Korean inpatients with delirium were administered prospectively a flexible dose of quetiapine. The delirium rating scale-revised-severity 98 (DRS-R-98) and clinical global impression scale-severity (CGI-s) scores were assessed at the time of pre- and post-treatment. The DRS-R-98 and CGI-s scores were significantly reduced by 57.3% and 55.1%, respectively. Quetiapine was effective and safe for the treatment of patients with delirium, and could be a useful alternative agent to classical antipsychotics in the treatment of delirium.
Pae
Chi-Un
CU
Department of Psychiatry, Kangnam St Mary's Hospital, The Catholic University of Korea College of Medicine, Banpo-Dong, Seocho-Gu, Seoul, South Korea.
Lee
Soo-Jung
SJ
Lee
Chang-Uk
CU
Lee
Chul
C
Paik
In-Ho
IH
D000368:Aged; D000369:Aged, 80 and over; D003693:Delirium / Q000188:drug therapy* / Q000523:psychology; D003987:Dibenzothiazepines / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011446:Prospective Studies; D000069348:Quetiapine Fumarate; D018709:Statistics, Nonparametric
D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate