Asynchronous delivery of twins and triplets with an interval period ranging from 48 hours to 19 weeks.
OBJECTIVE
To improve perinatal survival rates by prolonging the rest of the pregnancy after an abortion or extremely premature birth of one fetus in multiple pregnancies, especially in women with low fertility potential.


METHODS
Following the expulsion of one fetus a cervical cerclage was applied to all patients. The placenta of the expelled fetus including a small portion of its cord after it was ligated close to the external os, was left in situ. The patients were invariably kept on bed rest until the pregnancy was completed under close observation, tocolysis and preventive antibiosis. After the 24th week of gestation corticosteroids were administered.


RESULTS
The delivery interval achieved ranged between two and 135 days, the longest reported. Although the survival rate was relatively low (40%) all but one of the women (83%) managed eventually to have a live child, one with twins.


CONCLUSIONS
In selected multiple pregnancies the attempt to prolong the rest or the pregnancy, following the abortion or the extremely premature birth of one fetus, seems efficacious and justified especially in women with a history of long-term infertility.
2nd University Department of Obstetrics and Gynaecology, Aristotle University, Hippokrateio Hospital, Thessaloniki, Greece.
J M
JM
Tzafettas
G
G
Farmakides
D
D
Delkos
G
G
Kalogiros
F
F
Gkoutzioulis
A
A
Psarra
M
M
Gaitani
M
M
Mamopoulos
D000022:Abortion, Spontaneous / Q000517:prevention & control*; D000328:Adult; D023802:Cerclage, Cervical; D005260:Female; D005313:Fetal Death; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D019102:Infant, Very Low Birth Weight; D011247:Pregnancy; D011272:Pregnancy, Multiple; D014310:Triplets; D014427:Twins