[Mastalgia treatment with tamoxifen].
OBJECTIVE
To evaluate efficacy and side effects of mastalgia treatment with tamoxifen.


METHODS
Women with moderate to severe mastalgia were elected. Age, relation of mastalgia with menses, tamoxifen doses, months of treatment, side effects and pain control with tamoxifen were analyzed for all cases.


RESULTS
One hundred and forty-one cases were evaluated. Patients between 41 and 50 years old (45.3%), with moderated (67.3%) and non cyclical mastalgia (70%) were the most frequent. Two to four moths were the usual time of treatment (78%) for pain control; 64 patients (45%) showed side effects (10 mg 9.7% and 20 mg 41.6%, p < 0.001), dizziness and cephalalgia were the most frequent, but only eight (5.6%) stopped treatment. Tamoxifen achieved pain control in 67% of patients.


CONCLUSIONS
Our results suggest that tamoxifen is an effective treatment to control moderate to severe mastalgia.
Servicio de Clínica de Mama, Hospital General Tacuba del ISSSTE.
Carlos Manuel
CM
Ortíz-Mendoza
Mario Alberto
MA
Lucas Flores
Enrique de Gaspe Domville
Ede G
Domville
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001941:Breast Diseases / Q000188:drug therapy*; D002648:Child; D005260:Female; D006801:Humans; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy*; D011446:Prospective Studies; D020845:Selective Estrogen Receptor Modulators / Q000627:therapeutic use*; D012720:Severity of Illness Index; D013629:Tamoxifen / Q000627:therapeutic use*
D020845:Selective Estrogen Receptor Modulators; D013629:Tamoxifen