Detection of acute Epstein Barr virus cerebellitis using sequential brain HMPAO-SPECT imaging.
We used Technetium-99m hexamethyl propylene amine oxime single-photon emission computed tomography (HMPAO-SPECT) and magnetic resonance imaging (MRI) to evaluate a 30-year-old woman who developed cerebellar dysfunction after infection with Epstein Barr virus. Although no abnormal findings were evident from a brain MRI, the HMPAO-SPECT revealed increased perfusion in both cerebellar hemispheres. The patient improved without specific treatment. Two sequential HMPAO-SPECTs showed gradually reduced hyperperfusion in the cerebellum, which was correlated with her clinical recovery. We suggest that brain HMPAO-SPECT may thus be useful for identifying acute cerebellitis and predicting its clinical outcome.
Department of Neurology, College of Medicine, The Catholic University of Korea, South Korea. pjw516@catholic.ac.kr
Jeong Wook
JW
Park
Young Bin
YB
Choi
Kwang Soo
KS
Lee
D000328:Adult; D002526:Cerebellar Diseases / Q000000981:diagnostic imaging*; D002531:Cerebellum / Q000098:blood supply / Q000000981:diagnostic imaging; D002540:Cerebral Cortex / Q000098:blood supply / Q000000981:diagnostic imaging; D004292:Dominance, Cerebral / Q000502:physiology; D018792:Encephalitis, Viral / Q000000981:diagnostic imaging*; D020031:Epstein-Barr Virus Infections / Q000000981:diagnostic imaging*; D005260:Female; D005500:Follow-Up Studies; D020234:Gait Ataxia / Q000000981:diagnostic imaging; D006801:Humans; D006940:Hyperemia / Q000000981:diagnostic imaging; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D009460:Neurologic Examination; D012039:Regional Blood Flow / Q000502:physiology; D012075:Remission, Spontaneous; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
D019690:Technetium Tc 99m Exametazime