Detection and characterization of HIV type 2 in Calcutta, India.
Since the first report of HIV/AIDS in India in 1986, continuous serosurveillance has been undertaken in all Indian states. Recently, five cases of HIV-2 infection have been detected in Calcutta, situated in the eastern part of India. The full-length envelope gene (2.5 kb) of one of the strains was amplified, cloned, and sequenced. Phylogenetic analysis of the Calcutta HIV-2 envelope revealed a close relatedness to the HIV-2 Rod sequence isolated in offshore Senegal. This strain, however, showed a genetic diversity of 13.5% to other Indian HIV-2 isolates.
National Institute of Cholera and Enteric Diseases, Calcutta, India.
Payel
P
Bhanja
Dibya Kanti
DK
Mandal
S
S
Jana
S K
SK
Bhattacharya
S
S
Chakrabarti
D000328:Adult; D000595:Amino Acid Sequence; D015699:HIV Envelope Protein gp120 / Q000737:chemistry* / Q000235:genetics*; D015658:HIV Infections / Q000453:epidemiology / Q000821:virology*; D015498:HIV-2 / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA
D015699:HIV Envelope Protein gp120