Butenolides from a cultured microfungus, Acremonium sp.
Two related butenolides have been isolated from a culture broth of a strain of the fungus, Acremonium sp. Although the lactone acid (3) is a known compound, the structure of the lactone diacid (4), deduced by spectroscopic analysis, is assigned for the first time. This compound appears to be identical to a partly characterised metabolite isolated, along with 3, from Chaetomium indicum in 1953.
Chemistry, School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia. elg@chem.uwa.edu.au
Emilio L
EL
Ghisalberti
Jaih R
JR
Hargreaves
Elena
E
McConville
D015107:4-Butyrolactone / Q000031:analogs & derivatives; D000164:Acremonium / Q000737:chemistry*; D005663:Furans / Q000737:chemistry* / Q000302:isolation & purification*; D007166:Immunosuppressive Agents / Q000737:chemistry* / Q000302:isolation & purification*; D007783:Lactones / Q000737:chemistry; D013057:Spectrum Analysis
D005663:Furans; D007166:Immunosuppressive Agents; D007783:Lactones; C004511:butenolide; D015107:4-Butyrolactone