Microchip countercurrent electroseparation.
We report a microchip-based method for separating charged molecules according to electrophoretic mobility. The method is based on opposed electroosmotic, electrophoretic and convective forces. Similar to isoelectric focusing, solute can be accumulated into stationary zones, but without use of ampholytes. The method of "microchip countercurrent electroseparation" described here has potential application in the design of microfluidic separation chips.
Ista
Linnea K
LK
Department of Chemical and Nuclear Engineering, University of New Mexico, Albuquerque 87131, USA.
Lopez
Gabriel P
GP
Ivory
Cornelius F
CF
Ortiz
Moises J
MJ
Schifani
Thomas A
TA
Schwappach
Christopher D
CD
Sibbett
Scott S
SS