Initial and follow-up results of the European Seaquence coronary stent registry.
The primary objective of the present study was to assess the feasibility and the safety of the Seaquence stent (CathNet-Science) deployment for the treatment of coronary artery disease and the event-free survival of patients treated with this coronary stent. The study was conducted as a multicenter, prospective, observational registry. Patients with stable or unstable angina pectoris who were candidates for percutaneous coronary intervention with elective stenting of one single de novo lesion in a native coronary artery > or =3 mm in diameter were included in the study. Clinical follow-up was performed at 1 month and 9 months. Major adverse coronary events (MACE), that is, cardiac death, myocardial infarction, and target vessel revascularization (re-PTCA or CABG), were recorded over a period of 9 months. Using this stent, a 99% in-hospital success rate was achieved. A total of 17 patients presented MACE (8.7%) during the whole follow-up period and target lesion revascularization was needed for 14 (7.1%) patients. Using multivariate analysis only some clinical parameters (patients treated for unstable angina, with a history of CABG or of female gender) were found as independent predictors of MACE after coronary stenting. Procedural related factors, angiographic characteristics, or reference diameter were not found to influence clinical outcome. Because the study was performed in patients with a high proportion of complex lesions (relative high-risk nonselected population with nearly one third calcified lesions, many long and type B2 and C lesions) we can conclude that the coronary Seaquence stent can be considered as a stent of reference in routine practice.
Service des Maladies du Coeur et des Vaisseaux, Avenue Côte de Nacre, CHU de Caen, 14-033 Caen Cedex, France. hamon.m@chu-caen.fr
Martial
M
Hamon
Virgil
V
Petrescu
Philippe
P
Rossi
Phillipe
P
Commeau
Olivier
O
Wittenberg
Bernard
B
Jouve
Philippe
P
Brunel
Antoine
A
Gommeau
Carlos
C
Macaya
Amedeo
A
Betriu
Antonio
A
Serra
Maurizio
M
Viecca
Alessandro
A
Bortone
Antonio
A
Marzocchi
Ulrich
U
Bush
Eberhard
E
Grube
Heiner
H
Blanke
Eckart
E
Fleck
Gilles
G
Grollier
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000789:Angina, Unstable / Q000145:classification / Q000401:mortality / Q000628:therapy; D015906:Angioplasty, Balloon, Coronary; D019917:Blood Vessel Prosthesis Implantation; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D020878:Device Removal; D018572:Disease-Free Survival; D004869:Equipment Safety; D005060:Europe; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality / Q000601:surgery; D011446:Prospective Studies; D012008:Recurrence; D012042:Registries; D012086:Reoperation; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome