Tumour vaccine associated lymphadenopathy and false positive positron emission tomography scan changes.
A patient receiving intradermal injections of vaccine directed towards carcinoembryonic antigen-bearing metastases from colorectal cancer showed uptake of 18F-fluorodeoxyglucose in local draining lymph nodes during the course of treatment. This appearance should be considered as a possible false positive in patients undergoing such treatment who are being investigated with PET scans.
Gastrointestinal Department, Royal Marsden Hospital, Down's Road, Sutton, Surrey SM2 5PT, UK.
R L
RL
Jones
D
D
Cunningham
G
G
Cook
P J
PJ
Ell
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001365:Axilla; D019496:Cancer Vaccines / Q000009:adverse effects*; D002272:Carcinoembryonic Antigen / Q000378:metabolism; D015179:Colorectal Neoplasms; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary; D008206:Lymphatic Diseases / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D014055:Tomography, Emission-Computed
D019496:Cancer Vaccines; D002272:Carcinoembryonic Antigen