[Expression changes of tau protein and microtubule-associated proteins in testis intersitium of rats].
OBJECTIVE
To examine the expression of the tau protein and microtubule-associated proteins in the testis interstitium of aged and young rats.


METHODS
Sprague-Dawley male rats were divided into a young group(6 months, n = 10) and an aged group(28 months, n = 10). The two steps immunohistochemistry method with the antibody against tau protein and MAP alpha was performed on the testis tissues of the rats.


RESULTS
The results showed that the immunoreactive cells of tau protein of the testis interstilial of the aged rats obviously increased(P < 0.001) than those of the young, while the immunoreactive cells of the microtubule-associated proteins decreased(P < 0.01) in the aged.


CONCLUSIONS
The changes in the expression of the tau protein and microtubule-associated proteins may be related to the aging process of the testis.
Family Planning Institute, Tongji Medical College of Huazhong Science and Technology University, Wuhan, Hubei 430030, China.
Zilong
Z
Liu
Gang
G
Wang
Wanhong
W
Zhang
Shenghong
S
Liu
Xiaoli
X
Wang
Fang
F
Wang
Xuejun
X
Kang
D000375:Aging / Q000378:metabolism*; D000818:Animals; D007150:Immunohistochemistry; D008297:Male; D008869:Microtubule-Associated Proteins / Q000032:analysis*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013737:Testis / Q000737:chemistry*; D016875:tau Proteins / Q000032:analysis*
D008869:Microtubule-Associated Proteins; D016875:tau Proteins