Analysis of an agmatine deiminase gene cluster in Streptococcus mutans UA159.
An operon encoding enzymes of the agmatine deiminase system (AgDS) has been identified in the cariogenic bacterium Streptococcus mutans UA159. The AgDS is regulated by agmatine induction and carbohydrate catabolite repression. Ammonia is produced from agmatine at low pH, suggesting that the AgDS could augment acid tolerance.
Department of Oral Biology, University of Florida, Gainesville, Florida 32610, USA.
Ann R
AR
Griswold
Yi-Ywan M
YY
Chen
Robert A
RA
Burne
D000376:Agmatine / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D006867:Hydrolases / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D005810:Multigene Family; D017422:Sequence Analysis, DNA; D013295:Streptococcus mutans / Q000201:enzymology* / Q000254:growth & development
D000376:Agmatine; D006867:Hydrolases; C019626:agmatine deiminase