Mycosis fungoides mimicking inflammatory linear verrucous epidermal nevus.
We experienced an unusual case of mycosis fungoides with the clinical and histological features mimicking inflammatory linear verrucous epidermal nevus (ILVEN) in an 11-year-old boy. Localized linear multiple pruritic verrucous confluent papules and plaques appeared on the his left elbow, forearm and hand for 7 months. Skin biopsies showed characteristic findings of mycosis fungoides (e.g. Pautrier's microabscesses, follicular epitheliotropism, wiry bundles of collagen, etc.). T-cell receptor gene rearrangement analysis in the lesional skin demonstrated rearrangement of the gamma chain. RePUVA (systemic PUVA with retinoic acid) therapy improved his skin lesions and pruritus, but these progressed after discontinuation of treatment. Thus, lesions mimicking ILVEN can be an unusual and potentially misleading presentation of mycosis fungoides.
Jang
J-G
JG
Department of Dermatology, Kosin Medical College, 34 Amnam-Dong, Seo-ku, Busan 602-702, South Korea.
Sim
H-J
HJ
Kim
S-H
SH
Doh
K-S
KS
Jang
M-S
MS
Suh
K-S
KS
Kim
S-T
ST
D002648:Child; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D009182:Mycosis Fungoides / Q000175:diagnosis* / Q000473:pathology; D009506:Nevus / Q000175:diagnosis* / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014860:Warts / Q000175:diagnosis / Q000473:pathology