Incidence, timing and site of infections among pancreas transplant recipients.
The incidence, timing and site of infections among the different categories of pancreas transplant recipients were investigated. Patients were divided into three groups: pancreas transplant alone (PTA), pancreas after kidney transplant (PAK), or simultaneous pancreas and kidney (SPK) transplants. Length of follow-up, time to death, pancreas graft survival, incidence, timing and site of bacterial infections were noted. Our study showed that at least 75% of pancreas transplant recipients experienced at least one infection (range from 77.8% in the PTA group to 86.7% in the PAK group). The SPK group presented the highest rate of infections with 35.1 infections per 1000/patient-days. Symptomatic urinary tract infections were the most common cause of infection in all patients. The incidence of infections was higher during the first month after transplantation, except for the SPK transplant group, where infections occurred over a longer time period.
Department of Internal Medicine, Yale University School of Medicine and Yale New Haven Hospital, New Haven, CT 06510, USA. mattba@tin.it
M
M
Bassetti
P R O
PR
Salvalaggio
J
J
Topal
M I
MI
Lorber
A L
AL
Friedman
V T
VT
Andriole
G P
GP
Basadonna
D000328:Adult; D001424:Bacterial Infections / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D015994:Incidence; D016030:Kidney Transplantation / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D016035:Pancreas Transplantation / Q000009:adverse effects*; D013997:Time Factors