[Effects of millimeter wave combined with gamma-ray radiation on human tongue squamous cell carcinoma cell].
OBJECTIVE
To observe the effects of millimeter wave combined with (60)Co gamma-ray radiation on human tongue squamous cell carcinoma cell(Tca8113).


METHODS
Using mm-wave combined with (60)Co gamma-ray to irradiate Tca8113 cell suspensions. The colony forming inhibition efficiency was observed three weeks later. 24 hours after radiation, the samples were observed under electron microscope.


RESULTS
The study showed that the radiation could result in significant decrease of the colony forming efficiency (P<0.001). The inhibition efficiency was higher when the samples were exposed to high power density mm-wave or for a long duration (P<0.05 or P<0.01). The inhibiting effect in combined groups was more obvious than in singly radiated group (P<0.001 or P<0.05). There was no difference between 'R+HL' group and 'HL+R' group (P>0.05). Electron microscopy showed the cells' suprastructures had some injuries and regressive changes. And more serious changes existed in 'H' group.


CONCLUSIONS
It could be concluded that mm-wave radiation could efficiently inhibit the colony forming capability of Tca8113 cell. And mm-wave radiation could lead to morphological changes of exterior or interior ultrastructures of Tca8113 cell.
Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, Shanghai Second Medical University, Shanghai 200011, China. tangyj@online.sh.cn
Y J
YJ
Tang
Z H
ZH
Wang
X J
XJ
Zhou
R G
RG
He