[Characteristics of nitric oxide profile in new cases of focal infiltrative pulmonary tuberculosis].
Nitric oxide (NO) is the molecule that is one of the main elements of the antipathogenic activity of phagocytes that are involved in the provision of the body's resistance to the penetration and development of infections, including tuberculous one. The levels of final NO metabolites (nitrites and nitrates) in the blood, bronchoalveolar lavage fluid, and cultured alveolar macrophageal supernatant were measured during examination of 74 patients with focal and infiltrative pulmonary tuberculosis. There were decreased levels of final NO metabolites in all biological fluids in the examinees as compared with healthy individuals. The degree of the decreases in NO concentrations correlated with the severity and extent of a specific pulmonary process; it was the least in focal tuberculosis and the greatest in the infiltrative process with decay.
Ratnikov
V I
VI
Bubochkin
B P
BP
Potapov
I V
IV
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009569:Nitric Oxide / Q000378:metabolism*; D014397:Tuberculosis, Pulmonary / Q000097:blood / Q000378:metabolism* / Q000473:pathology
D009569:Nitric Oxide