Peritoneal carcinomatosis in refractory seminoma.
Intraperitoneal metastasis from a testicular germ cell tumor is very rare. We report a case in a 33-year-old man who was referred to Hokkaido University Hospital, Hokkaido, Japan, for further therapy for refractory seminoma. Physical examination revealed abdominal distension as a result of ascites, and cytology of the ascites showed seminoma cells. Although the ascites completely disappeared after treatment with a novel regimen of irinotecan-based chemotherapy, the patient had a recurrence of ascites and died of progressive disease 5 months after the start of the therapy.
Departments of Urology Surgical Pathology, Hokkaido University School of Medicine Department of Urology, Sapporo City General Hospital, Sapporo, Japan. takataka@rf6.so-net.ne.jp
Takashige
T
Abe
Nobuo
N
Shinohara
Tohru
T
Harabayashi
Kunihiko
K
Tsuchiya
Shin
S
Suzuki
Tomoo
T
Itoh
Toshimori
T
Seki
Masaki
M
Togashi
Karsuya
K
Nonomura
Tomohiko
T
Koyanagi
D000328:Adult; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D010534:Peritoneal Neoplasms / Q000556:secondary*; D018239:Seminoma / Q000556:secondary*; D013736:Testicular Neoplasms / Q000473:pathology*