Long-term dynamics of blood pressure in intact and sympathectomized post-suspension rats.
Low-frequency dynamics of mean arterial pressure (MAP) and pulse interval (PI) was studied in intact and sympathectomized rats after 2-week tail suspension. Correlation properties of long-term (f<0.8 Hz) MAP fluctuations were analyzed using R/S Hurst method. It was shown that time series of successive increments in MAP level display power-law fractal anticorrelations in wide range of time scales. After sympathectomy and/or suspension averaged Hurst exponents were more close to the value for uncorrelated random process (H=0.5), indicating deterioration of regulatory feedbacks. Besides, a decrease of coherence between MAP and PI in low-frequency range was observed after suspension in both intact and sympathectomized rats, indicating alteration of non-sympathetic cardiovascular control mechanisms.
Space Biomedical Center for Training and Research, Moscow, Russia.
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A
Borovik
O
O
Tarasova
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I
Figourina
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V
Golubinskaya
O
O
Vinogradova