[Preliminary study on arsenic trioxide induced Tca8113 cell apoptosis].
OBJECTIVE
To explore the possibility of arsenic trioxide inducing the apoptosis in the treatment of oral squamous cell carcinoma.


METHODS
Human tongue squamous cell carcinoma cell line Tca8113 was used for in vitro studies. The effect of arsenic trioxide on oral squamous cell carcinoma was studied by using flow cytometry, fluoroscope and electric microscope.


RESULTS
Arsenic trioxide induced Tca8113 cell apoptosis, while inhibiting the growth and survival.


CONCLUSIONS
Arsenic trioxide might be one drug of inducing apoptosis in the treatment of oral squamous cell carcinoma.
Department of Oral & Maxillofacial Surgery, Ninth People's Hospital, Shanghai Second Medical University, Shanghai 200001, China.
Yue-ping
YP
Wang
Han-guang
HG
Zhu
Zhi-yuan
ZY
Zhang