Structural elucidation of fritillahupehin from bulbs of Fritillaria hupehensis Hsiao et K.C. Hsia.
A novel diterpenoid ester, fritillahupehin (1) and three known fatty acids, palmitic acid (2), lignoceric acid (3) and azelaric acid (4), have been isolated from the bulbs of Fritillaria hupehensis Hsiao et K.C. Hsia. The structure of fritillahupehin has been established to be ent-kauran-16beta-yl lignocerate by means of spectroscopic and chemical evidence. Compounds 2-4 were isolated from Fritillaria sp. for the first time.
Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China.
Yong-Hui
YH
Zhang
Han-Li
HL
Ruan
Hui-Fang
HF
Pi
Ji-Zhou
JZ
Wu
Han-Dong
HD
Sun
Tetsuro
T
Fujita
D004224:Diterpenes; D004952:Esters; D005227:Fatty Acids / Q000302:isolation & purification; D031410:Fritillaria / Q000737:chemistry*; D019308:Palmitic Acid / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry; D013057:Spectrum Analysis
D004224:Diterpenes; D004952:Esters; D005227:Fatty Acids; C485255:fritillahupehin; D019308:Palmitic Acid; C010210:lignoceric acid