Estimation of a change point in a hazard function based on censored data.
The hazard function plays an important role in reliability or survival studies since it describes the instantaneous risk of failure of items at a time point, given that they have not failed before. In some real life applications, abrupt changes in the hazard function are observed due to overhauls, major operations or specific maintenance activities. In such situations it is of interest to detect the location where such a change occurs and estimate the size of the change. In this paper we consider the problem of estimating a single change point in a piecewise constant hazard function when the observed variables are subject to random censoring. We suggest an estimation procedure that is based on certain structural properties and on least squares ideas. A simulation study is carried out to compare the performance of this estimator with two estimators available in the literature: an estimator based on a functional of the Nelson-Aalen estimator and a maximum likelihood estimator. The proposed least squares estimator tums out to be less biased than the other two estimators, but has a larger variance. We illustrate the estimation method on some real data sets.
Université Catholique de Louvain, Belgium. gijbels@stat.ucl.ac.be
Irène
I
Gijbels
Ulkü
U
Gürler
D015982:Bias; D003627:Data Interpretation, Statistical; D006801:Humans; D016018:Least-Squares Analysis; D016013:Likelihood Functions; D008432:Mathematical Computing; D016016:Proportional Hazards Models; D011897:Random Allocation; D016019:Survival Analysis; D013997:Time Factors