Statin-associated rhabdomyolysis triggered by grapefruit consumption.
Dreier
Jens P
JP
Department of Neurology, Charité Hospital, University Medicine Berlin, Germany. jens.dreier@charite.de
Endres
Matthias
M
D000328:Adult; D000924:Anticholesteremic Agents / Q000009:adverse effects* / Q000493:pharmacokinetics; D032083:Citrus paradisi / Q000009:adverse effects*; D051544:Cytochrome P-450 CYP3A; D065607:Cytochrome P-450 Enzyme Inhibitors; D004791:Enzyme Inhibitors / Q000009:adverse effects / Q000494:pharmacology; D005260:Female; D011564:Furocoumarins / Q000009:adverse effects / Q000494:pharmacology; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000188:drug therapy; D008658:Inactivation, Metabolic; D012206:Rhabdomyolysis / Q000139:chemically induced*; D019821:Simvastatin / Q000009:adverse effects* / Q000493:pharmacokinetics
D000924:Anticholesteremic Agents; D065607:Cytochrome P-450 Enzyme Inhibitors; D004791:Enzyme Inhibitors; D011564:Furocoumarins; D019821:Simvastatin; C104464:CYP3A protein, human; D051544:Cytochrome P-450 CYP3A