Ultrasonic device for the noninvasive diagnosis of compartment syndrome.
An ultrasonic device for the diagnosis of acute compartment syndrome is described and results on six human cadaveric legs are presented. The ultrasonic device uses a pulsed phase locked loop (PPLL) to measure sub-micrometer displacements of the fascia wall. These displacements occur as a result of volume expansion of the muscle compartment of the lower leg and are related to changes in intramuscular pressure (IMP). In the cadaveric tests, the PPLL detected changes in compartment diameter resulting from IMP changes of 1 mmHg and from infusions of 0.25 ml saline increments. Based on these results, the ultrasonic PPLL appears to have the potential to become a low-cost, portable and noninvasive alternative to current methods for diagnosing acute compartment syndrome.
Luna Innovations, Inc., 130 Research Drive, Hampton, VA 23666, USA. lyncht@lunainnovations.com
John E
JE
Lynch
Joseph S
JS
Heyman
Alan R
AR
Hargens
D000208:Acute Disease; D002102:Cadaver; D003161:Compartment Syndromes / Q000000981:diagnostic imaging* / Q000473:pathology; D003936:Diagnosis, Computer-Assisted; D006801:Humans; D011312:Pressure; D014465:Ultrasonics; D014463:Ultrasonography