[Histomorphometric osseointegration evaluation of hydroxyapatite-coated and non-coated implants in dogs].
OBJECTIVE
Some reports showed the benefits of dental implants coated with hydroxyapatite, while some other studies found no significant difference between HA-coated implants and non-coated implants. The present study was to examine the osseointegration of HA-coated and non-coated implants in dogs.


METHODS
Twelve implants, 6 HA-coated and 6 non-coated were placed into mandibles of six dogs after teeth extraction. Animals were sacrificed after 1, 3, 6 months, respectively. Initial healing and the bone-implant interface were histomorphometrically assessed using light microscopy.


RESULTS
All implants osseointegrated; however, the ingrowth and development of new bone tissue onto HA-coated implants surface were sooner than that of non-coated ones. The index of bone osseointegration of HA-coated implants was higher than that of non-coated ones. After 1,3,6 months the osseointegration of HA-coated implants were 71.68%, 86.81%, 90.19%; While the non-coated ones'were 53.26%, 66.16%, 68.72%. The differences of them were very significant.


CONCLUSIONS
HA-coated implants enhanced initial bone tissue ingrowth and development and thus benefited the osseointegration of implants.
He
Yong-xin
YX
Department of Dentistry, The Traditional Chinese Medical Hospital of Jiading District, Shanghai 201821, China. heyongxin@yahoo.com
Gu
Yun-feng
YF
Cao
Hai-ping
HP
Chang
Cheng-kang
CK
Mao
Da-li
DL