Introductory lecture: from biomolecules to biodiagnostics: spectroscopy does it all.
Optical spectroscopy and imaging have been used in medicine since medicine was first practised. However, the more sophisticated instrumental methods now under development have made little impact on clinical medicine. In this paper a brief overview of the development of optical diagnostics is presented, highlighted by some successful pre-clinical applications. The reasons for the slow penetration of optical diagnostics into clinical practice are discussed.
Jackson
Michael
M
Institute for Biodiagnostics, National Research Council Canada, 435 Ellice Ave., Winnipeg, Manitoba, Canada R3B 1 Y6.
D003933:Diagnosis; D003952:Diagnostic Imaging / Q000266:history / Q000639:trends*; D049669:History, 16th Century; D049670:History, 17th Century; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology; D013057:Spectrum Analysis / Q000266:history / Q000639:trends*