Challenges for clinical genetic DNA testing.
DNA testing was first used in the late 1970s. Today, the indications for a DNA test have expanded to include predicting the development of genetic disorders, screening populations, confirming clinical diagnoses, prenatal testing and DNA testing to individualize medical treatment. Apart from the wide range of indications, the next few years will see a great expansion in the number of DNA tests. This will be driven by information generated from the Human Genome Project. Improved technology will make DNA testing more accessible. In this climate, the challenges will be considerable, particularly in relation to education. The avoidance of ethical, legal and social dilemmas will require informed and wise input from professionals and the community.
Trent
Ronald J A
RJ
Department of Molecular and Clinical Genetics, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050, Australia. rtrent@med.usyd.edu.au
Yu
Bing
B
Caramins
Melody
M
D019295:Computational Biology; D005817:Genetic Counseling; D005820:Genetic Testing / Q000941:ethics / Q000379:methods; D005826:Genetics, Medical; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000706:statistics & numerical data; D019095:Point-of-Care Systems