Bowdichine, a new diaza-adamantane alkaloid from Bowdichia virgilioides.
A novel alkaloid named bowdichine (1), only the third with a diaza-adamantane skeleton containing an unusual N-acetyl enamine moiety, and the known alkaloids acosmine (2), ormosanine (3) and podopetaline (4) have been isolated from the stem bark of Bowdichia virgilioides. The structures were elucidated on the basis of spectral data, mainly 1D and 2D NMR of the diaza-adamantane alkaloids 1 and 2.
Laboratório de Tecnologia Farmacêutica, Universidade Federal da Paraíba, C.P 5009, 58051-970, João Pessoa, PB, Brazil. jbarbosa@ltf.ufpb.br
José Maria
JM
Barbosa-Filho
Jackson Roberto Guedes
JR
Da Silva Almeida
Vicente Carlos
VC
De Oliveira Costa
Emídio Vasconcelos Leitão
EV
Da-Cunha
Marcelo Sobral
MS
Da Silva
Raimundo
R
Braz-Filho
D000218:Adamantane / Q000031:analogs & derivatives / Q000737:chemistry* / Q000302:isolation & purification*; D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification; D001372:Aza Compounds / Q000737:chemistry* / Q000302:isolation & purification*; D007887:Fabaceae / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy
D000470:Alkaloids; D001372:Aza Compounds; C485254:bowdichine; D000218:Adamantane