Anterior cingulum abnormalities in male patients with schizophrenia determined through diffusion tensor imaging.
OBJECTIVE
This study used diffusion tensor imaging to examine fractional anisotropy in the anterior cingulum and posterior cingulum bundles in patients with schizophrenia.


METHODS
Twenty-one male patients and 20 healthy comparison men were studied.


RESULTS
Reduced fractional anisotropy was seen for both sides of the anterior cingulum in the schizophrenia patients, who also exhibited less left-greater-than-right asymmetry in the anterior cingulum than was seen in the comparison subjects.


CONCLUSIONS
The findings suggest structural disconnections in the anterior cingulum in patients with schizophrenia.
Wang
Fei
F
Institute of Mental Health, Peking University, Beijing, China.
Sun
Zhiguo
Z
Cui
Liwei
L
Du
Xiangke
X
Wang
Xilin
X
Zhang
Hongyan
H
Cong
Zhong
Z
Hong
Nan
N
Zhang
Dai
D
D000704:Analysis of Variance; D016880:Anisotropy; D038524:Diffusion Magnetic Resonance Imaging; D004292:Dominance, Cerebral / Q000502:physiology; D006179:Gyrus Cinguli / Q000002:abnormalities* / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D009415:Nerve Net / Q000002:abnormalities / Q000473:pathology; D012016:Reference Values; D012559:Schizophrenia / Q000175:diagnosis* / Q000503:physiopathology; D012565:Schizophrenic Psychology