Placental site trophoblastic tumor of the uterine cervix occurring from undetermined antecedent pregnancy.
A cervical polyp complicated by severe hemorrhage was removed from a 43-year-old Japanese woman (gravida 0), who had undergone tubectomy on the right side 10 years previously. The polyp was diagnosed by immunohistochemical studies as placental site trophoblastic tumor of the cervix, but no metastatic foci were found in any other uterine site. The tumor was further demonstrated by PCR polymorphisms to possess two genomic DNA of the patient and her husband. Serum beta-hCG and urinary hCG titers were both low, which rapidly fell to 0.8 mIU/mL after a total hysterectomy and remained 0.2 mIU/mL after dismission. She has been uneventful for 3 years.
Josai Hospital, Ibaraki, Japan. somahr99@bj8.so-net.ne.jp
Hiroaki
H
Soma
Takahiko
T
Okada
Tsutomu
T
Yoshinari
Atsuo
A
Furuno
Seiichi
S
Yaguchi
Kazuo
K
Tokoro
Hidenori
H
Kato
D000328:Adult; D004247:DNA / Q000032:analysis; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D010920:Placenta; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011247:Pregnancy; D014328:Trophoblastic Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000601:surgery; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000601:surgery
D004247:DNA