Bowdichine, a new diaza-adamantane alkaloid from Bowdichia virgilioides.
A novel alkaloid named bowdichine (1), only the third with a diaza-adamantane skeleton containing an unusual N-acetyl enamine moiety, and the known alkaloids acosmine (2), ormosanine (3) and podopetaline (4) have been isolated from the stem bark of Bowdichia virgilioides. The structures were elucidated on the basis of spectral data, mainly 1D and 2D NMR of the diaza-adamantane alkaloids 1 and 2.
Barbosa-Filho
José Maria
JM
Laboratório de Tecnologia Farmacêutica, Universidade Federal da Paraíba, C.P 5009, 58051-970, João Pessoa, PB, Brazil. jbarbosa@ltf.ufpb.br
Da Silva Almeida
Jackson Roberto Guedes
JR
De Oliveira Costa
Vicente Carlos
VC
Da-Cunha
Emídio Vasconcelos Leitão
EV
Da Silva
Marcelo Sobral
MS
Braz-Filho
Raimundo
R
D000218:Adamantane / Q000031:analogs & derivatives / Q000737:chemistry* / Q000302:isolation & purification*; D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification; D001372:Aza Compounds / Q000737:chemistry* / Q000302:isolation & purification*; D007887:Fabaceae / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy
D000470:Alkaloids; D001372:Aza Compounds; C485254:bowdichine; D000218:Adamantane