[Dimephosphon in complex therapy of acute edematous pancreatitis].
Clinical investigations of 120 patients have shown that Dimephosphon included in complex treatment of acute edematous pancreatitis facilitates more rapid arrest of the symptoms. An important effect of the drug is its ability to decrease the level of endogenous intoxication by both the hydrophilic and hydrophobic components. It was established that one of the mechanisms of favorable action of the drug is its ability to inhibit LPO, to decrease activity of phospholipase A2. The drug possessing the cytoprotecting effect promotes rapid restoration of the functional state of the liver, in particular its detoxicating, albumin synthesizing ability that is not least of the factors of optimization of the complex therapy.
A I
AI
Vlasov
V A
VA
Berezin
A V
AV
Gerasimenko
L M
LM
Mosina
I V
IV
Saushev
D000208:Acute Disease; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004487:Edema / Q000209:etiology*; D006801:Humans; D009943:Organophosphorus Compounds / Q000627:therapeutic use*; D010182:Pancreatic Diseases; D010195:Pancreatitis / Q000150:complications* / Q000188:drug therapy* / Q000601:surgery
D000894:Anti-Inflammatory Agents, Non-Steroidal; D009943:Organophosphorus Compounds; C049638:dimephosphon