Co-isolation of Trichosporon inkin and Candida parapsilosis from a scalp white piedra case.
White piedra is a rare fungal infection of the hair shaft characterized by small, firm, irregular white-brown nodules. The infection is caused by basidiomycetous yeasts in the genus Trichosporon. We report a case of a 28-year-old female patient who acquired the infection in Qatar. In this case, the scalp was the only site affected, but infection at that site was extensive. The hair had a Saccharomyces-like yeast odor and appeared to be beaded, with light-brown nodules of varying sizes up to 2 mm long. Trichosporon sp. accompanied by Candida parapsilosis grew out along hair shafts planted in primary isolation media. Molecular identification of the Trichosporon carried out by analyzing the 26S ribosomal gene gave a 100% match with Trichosporon inkin, a major cause of pubic white piedra. The patient was treated with daily applications of ketoconazole shampoo followed by econazole shampoo and cream, and was considered clinically and mycologically cured after 2 months. Novel findings in the present case are the first identification of T. inkin as an agent of scalp white piedra, and the heavy outgrowth of C. parapsilosis from the concretions, although in the latter case it is not clear if the co-occurring yeast was etiologically contributory to the pathogenesis of the white piedra.
Taj-Aldeen
Saad J
SJ
Department of Laboratory Medicine and Pathology, Division of Microbiology, Hamad Medical Corporation, Doha, Qatar. stajaldeen@hmc.org.qa
Al-Ansari
Hamda I
HI
Boekhout
Teun
T
Theelen
Bart
B
D000328:Adult; D002175:Candida / Q000302:isolation & purification*; D005260:Female; D006201:Hair Diseases / Q000382:microbiology*; D006801:Humans; D012536:Scalp Dermatoses / Q000382:microbiology*; D014250:Trichosporon / Q000235:genetics / Q000302:isolation & purification*