[Infiltrating mucinous carcinoma developed on chronic anal fistula; diagnostic and surgical difficulties].
Anal carcinoma is rare; fistula-in-ano is sometimes mentioned among other premalignant conditions. Chronic anal fistula is associated with malignant transformation to mucinous adenocarcinoma, difficult to diagnose in the anal region and associated to a poor prognosis. Malignant transformation to infiltrating colloid carcinoma was surprised during a one year period, in a patient with long-standing perianal fistula (24 years). Inflammatory changes of the perineal region and other peculiar characteristics (such as neoplastic spread following supurative pathways) were responsible for diagnostic and surgical difficulties.
Spital Clinic Sfânta Maria, Clinica Chirurgie, bd. Ion Mihalache nr. 37-39, sector 1, Bucureşti, 78218.
I N
IN
Mateş
Daniela
D
Dinu
Georgeta
G
Rădulescu
Cristina
C
Iosif
D002288:Adenocarcinoma, Mucinous / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D001005:Anus Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D002908:Chronic Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D012003:Rectal Fistula / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D016896:Treatment Outcome