The eutD gene of Salmonella enterica encodes a protein with phosphotransacetylase enzyme activity.
The EutD protein of Salmonella enterica is homologous to the catalytic domain of the phosphotransacetylase (Pta) enzyme. The Pta-like activity level of the EutD enzyme compared favorably to that of other Pta enzymes. High-pressure liquid chromatography and mass spectrometry verified that acetyl-coenzyme A was the product of the reaction. The EutD protein restored growth of an S. enterica pta strain on acetate as the source of carbon and energy.
Brinsmade
Shaun R
SR
Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin 53726, USA.
Escalante-Semerena
Jorge C
JC
D000085:Acetates / Q000378:metabolism; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D003470:Culture Media; D013058:Mass Spectrometry; D010709:Phosphate Acetyltransferase / Q000235:genetics* / Q000378:metabolism*; D019779:Salmonella enterica / Q000201:enzymology / Q000235:genetics* / Q000254:growth & development
D000085:Acetates; D001426:Bacterial Proteins; D003470:Culture Media; D010709:Phosphate Acetyltransferase