Microbial glycosylation of four free anthraquinones by Absidia coerulea.
Absidia coerulea transformed four anthraquinones from rhubarb, chrysophanol, physcion, emodin and aloe-emodin to their corresponding glycosylated metabolites. The structures of the products were characterized as chrysophanol 8-O-beta-D-glucoside, physcion 8-O-beta-D-glucoside, emodin 6-O-beta-D-glucoside, and aloe-emodin 1-O-beta-D-glucoside, respectively.
The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xueyuan Road #38, Beijing 100083, PR China.
Wei
W
Zhang
Min
M
Ye
Jixun
J
Zhan
Yingjie
Y
Chen
Dean
D
Guo
D020095:Absidia / Q000378:metabolism*; D000880:Anthraquinones / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D004642:Emodin / Q000031:analogs & derivatives* / Q000737:chemistry; D006031:Glycosylation; D012250:Rheum / Q000737:chemistry*
D000880:Anthraquinones; D004365:Drugs, Chinese Herbal; C518327:aloe emodin; C008905:physcione; D004642:Emodin; C027113:chrysophanic acid