[Infiltrating mucinous carcinoma developed on chronic anal fistula; diagnostic and surgical difficulties].
Anal carcinoma is rare; fistula-in-ano is sometimes mentioned among other premalignant conditions. Chronic anal fistula is associated with malignant transformation to mucinous adenocarcinoma, difficult to diagnose in the anal region and associated to a poor prognosis. Malignant transformation to infiltrating colloid carcinoma was surprised during a one year period, in a patient with long-standing perianal fistula (24 years). Inflammatory changes of the perineal region and other peculiar characteristics (such as neoplastic spread following supurative pathways) were responsible for diagnostic and surgical difficulties.
Mateş
I N
IN
Spital Clinic Sfânta Maria, Clinica Chirurgie, bd. Ion Mihalache nr. 37-39, sector 1, Bucureşti, 78218.
Dinu
Daniela
D
Rădulescu
Georgeta
G
Iosif
Cristina
C
D002288:Adenocarcinoma, Mucinous / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D001005:Anus Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D002908:Chronic Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D012003:Rectal Fistula / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D016896:Treatment Outcome