Multiple labelled nanoparticles for bio detection.
Remote nanoparticle detection is required for the development of in situ biological probes. Here we describe the labelling of silver nanoparticles to produce multiply coded particles which can be detected by surface enhanced resonance Raman scattering (SERRS). There is a potential for thousands of codes to be written and read without the need for spatial resolution of components of the code. The use of these systems in bioanlaysis and in situ detection is discussed.
Department of Pure and Applied Chemistry, University of Strathclyde, Cathedral Street, Glasgow, UK G1 1XL.
Frances T
FT
Docherty
Maureen
M
Clark
Graeme
G
McNay
Duncan
D
Graham
W Ewen
WE
Smith
D002021:Buffers; D003102:Colloids; D017931:DNA Primers; D005456:Fluorescent Dyes; D008863:Microspheres; D009841:Oligonucleotides / Q000737:chemistry*; D012542:Scattering, Radiation; D013059:Spectrum Analysis, Raman
D002021:Buffers; D003102:Colloids; D017931:DNA Primers; D005456:Fluorescent Dyes; D009841:Oligonucleotides