Isolated ACTH deficiency with Graves' disease: a case report.
A 60-year-old man was hospitalized with complaints of general malaise and weight loss. On admission, ACTH and cortisol levels were low, and thyroid function tests revealed hyperthyroidism. These findings and further examination led to a diagnosis of isolated ACTH deficiency (IAD) with Graves' disease. It is known that IAD is frequently associated with thyroid disease, but its association with Graves' disease is rare. The present case is worth noting, because some reports indicate that aggravation of associated Graves' disease may concomitantly aggravate adrenal insufficiency in patients with IAD.
Department of Internal Medicine, Uwajima Municipal Hospital, Ehime, Japan.
Shozo
S
Miyauchi
Yoshimasa
Y
Yamashita
Bunzo
B
Matsuura
Morikazu
M
Onji
D000324:Adrenocorticotropic Hormone / Q000097:blood / Q000172:deficiency*; D003348:Cortisone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006111:Graves Disease / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008875:Middle Aged; D013960:Thyroid Function Tests
D000324:Adrenocorticotropic Hormone; D003348:Cortisone; D006854:Hydrocortisone