26th Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, USA, 3-6 December 2003: update on preclinical and translational research.
The San Antonio Breast Cancer Symposium is the largest annual meeting devoted solely to breast cancer research. The late William L McGuire's vision for this meeting was to stimulate 'translational research', many years before this term became popular. In this way, the San Antonio Breast Cancer Symposium represents a forum in which basic and clinical researchers present their research side by side. Each year sees the continued evolution of our understanding of the basic mechanisms of breast cancer initiation and progression, and the clinical application of this knowledge. Major topics of discussion at the symposium this year were the cell cycle, new evolving concepts of estrogen receptor action, breast cancer stem cells, new predictive and prognostic markers (including microarray studies), and continued exploration of the mechanisms of drug resistance. This report will summarize preclinical and translational highlights from the meeting.
Lee
Adrian V
AV
Breast Center, Baylor College of Medicine and the Methodist Hospital, Houston, Texas, USA. avlee@breastcenter.tmc.edu
Chamness
Gary
G
Oesterreich
Steffi
S
D001943:Breast Neoplasms / Q000235:genetics*; D002453:Cell Cycle / Q000235:genetics; D019008:Drug Resistance, Neoplasm / Q000235:genetics; D020869:Gene Expression Profiling / Q000379:methods; D015972:Gene Expression Regulation, Neoplastic / Q000235:genetics; D019398:Genes, BRCA1; D052138:Genes, Neoplasm / Q000235:genetics; D005819:Genetic Markers / Q000235:genetics; D006801:Humans; D014411:Neoplastic Stem Cells / Q000737:chemistry / Q000378:metabolism; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods; D011237:Predictive Value of Tests; D011379:Prognosis; D011960:Receptors, Estrogen / Q000235:genetics; D017978:Receptors, Growth Factor / Q000235:genetics; D013781:Texas
D005819:Genetic Markers; D011960:Receptors, Estrogen; D017978:Receptors, Growth Factor