Corticosteroid treatment in meconium aspiration syndrome: a solution for better outcome?
Corticosteroid treatment in severe meconium aspiration syndrome may afford, especially if started early, some improvement in oxygenation, lung function and pulmonary haemodynamics during the acute phase of the disorder. Still, the effects of corticosteroids on lung tissue perturbations and outcome of diseased infants remain unclear.


CONCLUSIONS
Further research is needed to determine the clinical significance and optimal timing and dosing of corticosteroid treatment in severe meconium aspiration syndrome.
Research Centre of Applied and Preventive Cardiovascular Medicine, Department of Paediatrics, University of Turku, Turku, Finland. kape@utu.fi
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Kääpä
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000818:Animals; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008471:Meconium Aspiration Syndrome / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D013552:Swine
D000305:Adrenal Cortex Hormones