Escherichia coli proton-translocating F0F1-ATP synthase and its association with solute secondary transporters and/or enzymes of anaerobic oxidation-reduction under fermentation.
The Escherichia coli proton-translocating F0F1-ATP synthase has a priority in H+ circulation through the membrane in maintaining proton-motive force in the context of ATP synthesis and hydrolysis. Recent advances in the study of this complex under fermentative growth have led to hypothesis that, in the absence of oxidative phosphorylation, F0F1 is implicated as an essential part of H+ movement and ATP hydrolysis, associated with solute secondary transporters and/or enzymes of anaerobic oxidation-reduction. These associations can result from a protein-protein interaction by dithiol-disulfide interchange. In such associations F0F1 has novel functions in bacterial cell physiology.
Trchounian
Armen
A
Department of Biophysics of the Biological Faculty, Yerevan State University, 1 A. Manoukian Street, 375049 Yerevan, Armenia. Trchounian@ysu.am
D000332:Aerobiosis; D000693:Anaerobiosis; D001386:Azides / Q000494:pharmacology; D002352:Carrier Proteins / Q000378:metabolism*; D003593:Cytoplasm / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000494:pharmacology; D004926:Escherichia coli / Q000201:enzymology* / Q000254:growth & development / Q000378:metabolism; D029968:Escherichia coli Proteins / Q000378:metabolism; D005285:Fermentation; D005560:Formate Dehydrogenases / Q000378:metabolism; D006864:Hydrogenase / Q000378:metabolism; D017136:Ion Transport; D007700:Kinetics; D009097:Multienzyme Complexes / Q000378:metabolism; D010084:Oxidation-Reduction; D011188:Potassium / Q000378:metabolism; D021122:Protein Subunits; D018892:Proton-Motive Force; D006180:Proton-Translocating ATPases / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000378:metabolism*
D001386:Azides; D002352:Carrier Proteins; D004791:Enzyme Inhibitors; D029968:Escherichia coli Proteins; D009097:Multienzyme Complexes; D021122:Protein Subunits; D006864:Hydrogenase; D005560:Formate Dehydrogenases; C054017:formate hydrogenlyase; D006180:Proton-Translocating ATPases; D011188:Potassium