The need for trial identifiers.
The medical literature is distorted by publication bias, duplicate publication and under-reporting of clinical trials. This can create problems in systematic numbering systems. The inclusion of trial identifiers reviews and meta-analysis which are increasingly used as the basis for evidence-based guidelines and therefore for treatment decisions. Various schemes for identifying trials and their associated publications are reviewed. These include trial registers and trial in all publications could greatly enhance the value of the medical literature and increase the robustness of systematic reviews and meta-analyses.
Wager
Elizabeth
E
Sideview, Princes Risborough, UK. liz@sideview.demon.co.uk
D002986:Clinical Trials as Topic; D015713:Duplicate Publications as Topic; D032984:Ethics, Research; D019317:Evidence-Based Medicine; D006801:Humans; D007391:International Cooperation; D017594:Publication Bias; D011643:Publishing