Motor protein with nonequilibrium potential: Its thermodynamics and efficiency.
A nonequilibrium potential function is introduced for a motor protein modeled by a rectified Brownian motion. This result provides a concrete case for a class of nonequilibrium systems in steady state with dissipation which possess a potential function. The potential micro is a natural generalization of the chemical potential for isothermal chemical species and micro=const if and only if the system is in an equilibrium. The steady-state flux J proportional, variant - nabla micro, and the total heat dissipation h(d) equals a surface integral integral microJ.dS, representing the energy input. In terms of micro and h(d) the thermodynamic energy conservation in the mesoscopic stochastic system can be rigorously established and various types of motor efficiency are elucidated.
Department of Applied Mathematics, University of Washington, Seattle, Washington 98195, USA.
Hong
H
Qian
D000244:Adenosine Diphosphate / Q000737:chemistry; D000255:Adenosine Triphosphate / Q000737:chemistry* / Q000378:metabolism*; D003198:Computer Simulation; D004735:Energy Transfer / Q000502:physiology*; D008954:Models, Biological; D008956:Models, Chemical; D020409:Molecular Motor Proteins / Q000737:chemistry* / Q000502:physiology*; D009038:Motion; D011506:Proteins / Q000737:chemistry* / Q000502:physiology*; D013816:Thermodynamics
D020409:Molecular Motor Proteins; D011506:Proteins; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate