The eutD gene of Salmonella enterica encodes a protein with phosphotransacetylase enzyme activity.
The EutD protein of Salmonella enterica is homologous to the catalytic domain of the phosphotransacetylase (Pta) enzyme. The Pta-like activity level of the EutD enzyme compared favorably to that of other Pta enzymes. High-pressure liquid chromatography and mass spectrometry verified that acetyl-coenzyme A was the product of the reaction. The EutD protein restored growth of an S. enterica pta strain on acetate as the source of carbon and energy.
Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin 53726, USA.
Shaun R
SR
Brinsmade
Jorge C
JC
Escalante-Semerena
D000085:Acetates / Q000378:metabolism; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D003470:Culture Media; D013058:Mass Spectrometry; D010709:Phosphate Acetyltransferase / Q000235:genetics* / Q000378:metabolism*; D019779:Salmonella enterica / Q000201:enzymology / Q000235:genetics* / Q000254:growth & development
D000085:Acetates; D001426:Bacterial Proteins; D003470:Culture Media; D010709:Phosphate Acetyltransferase