Coagulation defects in trauma patients: etiology, recognition, and therapy.
Trauma patients have many reasons to have defects in coagulation. These can be caused by the trauma or because of pre-existing disorders. Trauma patients who are at risk for coagulation defects should be screened with the basic tests (aPTT, INR/PT, platelet counts, hematocrit, and fibrinogen), with therapy based on the results. Attention also should be paid to any other correctable factors such as hypothermia. Finally, pre-existing disorders can influence the patient's hemostasis greatly and may require specific therapies.
DeLoughery
Thomas G
TG
Division of Medical Oncology, L586 Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97201-3098, USA. delought@ohsu.edu
D001778:Blood Coagulation Disorders / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006801:Humans; D007035:Hypothermia / Q000150:complications*; D017713:Platelet Transfusion; D065227:Transfusion Reaction; D014947:Wounds and Injuries / Q000150:complications* / Q000628:therapy