Use of nesiritide (human B-type natriuretic peptide) in infants following cardiac surgery.
We report the use of nesiritide in two infants following cardiac surgery. Both infants had increased intracardiac filling pressures postoperatively, despite traditional afterload reduction and diuretics. Both infants demonstrated clinical improvement with nesiritide therapy. There is currently limited data available describing the use of nesiritide in infants.
Simsic
J M
JM
Sibley Heart Center Cardiology, Children's Healthcare of Atlanta, Emory University, Atlanta, GA 30329, USA. simsicj@kidsheart.com
Reddy
V S
VS
Kanter
K R
KR
Kirshbom
P M
PM
Forbess
J M
JM
D001017:Aortic Coarctation / Q000601:surgery; D001024:Aortic Valve Stenosis / Q000151:congenital / Q000601:surgery; D001794:Blood Pressure / Q000187:drug effects; D006348:Cardiac Surgical Procedures / Q000009:adverse effects; D006345:Heart Septal Defects, Ventricular / Q000601:surgery; D006801:Humans; D007223:Infant; D008944:Mitral Valve Insufficiency / Q000151:congenital / Q000601:surgery; D045283:Natriuretic Agents / Q000627:therapeutic use*; D020097:Natriuretic Peptide, Brain / Q000627:therapeutic use*; D013318:Stroke Volume / Q000187:drug effects; D017725:Ventricular Pressure / Q000187:drug effects
D045283:Natriuretic Agents; D020097:Natriuretic Peptide, Brain