Clinical evaluation of the vector algorithm for neonatal hearing screening using automated auditory brainstem response.
A novel auditory brainstem response (ABR) detection and scoring algorithm, entitled the Vector algorithm is described. An independent clinical evaluation of the algorithm using 464 tests (120 non-stimulated and 344 stimulated tests) on 60 infants, with a mean age of approximately 6.5 weeks, estimated test sensitivity greater than 0.99 and test specificity at 0.87 for one test. Specificity was estimated to be greater than 0.95 for a two stage screen. Test times were of the order of 1.5 minutes per ear for detection of an ABR and 4.5 minutes per ear in the absence of a clear response. The Vector algorithm is commercially available for both automated screening and threshold estimation in hearing screening devices.
Keohane
Bernie M
BM
Clinical Research Department, SLE Ltd., Croydon, Surrey, UK. bkeohane@sle.co.uk
Mason
Steve M
SM
Baguley
David M
DM
D000465:Algorithms; D001330:Electronic Data Processing; D016057:Evoked Potentials, Auditory, Brain Stem; D006320:Hearing Tests / Q000379:methods*; D006801:Humans; D007231:Infant, Newborn; D015997:Neonatal Screening / Q000379:methods*; D012680:Sensitivity and Specificity