Clostridium innocuum bacteremia secondary to infected hematoma with gas formation in a kidney transplant recipient.
Clostridium innocuum is a relatively antimicrobial resistant, frequently misidentified anaerobe that has only rarely been associated with bacteremia. A 38-year-old female with chronic hepatitis C underwent a second kidney transplant operation. Two weeks after surgery a computed tomography scan of the abdomen showed a heterogeneous hematoma with pockets of gas adjacent to the allograft, which extended into the pelvis and left abdominal wall, associated with low-grade fever. An anaerobic blood culture grew a Clostridium initially identified as C. subterminale and later re-identified as C. innocuum. At abdominal exploration liquefied blood was evacuated, and the patient completed a course of antibiotics and recovered. C. innocuum should be considered as a cause of gas-producing anaerobic infection in transplant patients. Because C. innocuum is frequently misidentified by the use of commercial anaerobic identification kits, its true incidence in serious infections is likely underestimated.
Department of Surgery, University of Pittsburgh Medical Center, The Thomas E. Starzl Transplantation Institute, Pittsburgh, Pennsylvania 15213, USA.
B
B
Castiglioni
A
A
Gautam
D M
DM
Citron
W
W
Pasculle
E J C
EJ
Goldstein
D
D
Strollo
M
M
Jordan
S
S
Kusne
D000328:Adult; D016470:Bacteremia / Q000209:etiology*; D003013:Clostridium / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000209:etiology*; D005260:Female; D006406:Hematoma / Q000150:complications*; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D014184:Transplantation, Homologous