Tumor-induced rickets: usefulness of MR gradient echo recall imaging for tumor localization.
An 11-year-old boy presented with a femur fracture, bone hypomineralization, and hypophosphatemia, suggesting tumor-induced rickets. Conventional radiologic techniques including magnetic resonance skeletal survey did not identify a tumor. Magnetic resonance gradient echo recall imaging demonstrated a 3-cm iliac tumor, the resection of which rapidly reversed metabolic abnormalities. This technique may be useful in identifying elusive tumors associated with tumor-induced rickets.
Shulman
Dorothy I
DI
Departments of Pediatrics, Orthopedics, Radiology, and Pathology, All Children's Hospital, St Petersburg, Florida USA.
Hahn
Gregory
G
Benator
Richard
R
Washington
Kenneth
K
White
Kenneth E
KE
Farber
Joshua
J
Econs
Michael J
MJ
D001859:Bone Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D002648:Child; D000089703:Fibroblast Growth Factor-23; D005346:Fibroblast Growth Factors / Q000032:analysis* / Q000097:blood; D006393:Hemangiopericytoma / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D006801:Humans; D007085:Ilium; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012279:Rickets / Q000209:etiology
D005346:Fibroblast Growth Factors; D000089703:Fibroblast Growth Factor-23