EEG patterns in persons exposed to ionizing radiation as a result of the chernobyl accident. Part 2: quantitative EEG analysis in patients who had acute radiation sickness.
Cross-sectional quantitative electroencephalogram (qEEG) study (1996-2001) among Chernobyl accident survivors, who had confirmed acute radiation sickness and were irradiated in dose of 1-5 Gy, revealed the neurophysiological markers of ionizing radiation. Neuropsychological markers were: left fronto-temporal dominant frequency reduction; absolute delta-power lateralization to the left (dominant) hemisphere; relative delta-power increase in the fronto-temporal areas; absolute theta-power decrease in the left temporal region; absolute and relative alpha-power diffusive decrease, which may reflect cortico-limbic dysfunction lateralized to the left, dominant hemisphere, with the fronto-temporal cortical and hippocampal damage. Quantitative electroencephalogram proposed for differentiation of radiation and nonradiation brain damages and as a new biological dosymetry method. High radiosensitivity of the brain, neocortex, and dominant hemisphere higher radiosensitivity are discussed.
Loganovsky
Konstantin N
KN
Department of Radiation Psychoneurology, Instiute of Clinical Radiology, Scientific Center for Radiation Medicine of Academy of Medical Sciences of Ukraine, Kiev. logan@rcrm.kiev.ua
Yuryev
Konstantin L
KL
D001931:Brain Mapping; D002540:Cerebral Cortex / Q000002:abnormalities / Q000503:physiopathology / Q000528:radiation effects*; D003430:Cross-Sectional Studies; D004307:Dose-Response Relationship, Radiation; D004569:Electroencephalography; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D011832:Radiation Injuries / Q000453:epidemiology / Q000503:physiopathology*; D011839:Radiation, Ionizing; D018788:Radioactive Hazard Release; D012426:Russia