Nonlinear viscoelasticity in rabbit medial collateral ligament.
The goal of this study was to characterize the viscoelastic behavior of the rabbit medial collateral ligament (MCL) at multiple levels of strain (between 0% and approximately 5%) and their corresponding stresses (between 0 and approximately 55 MPa) for stress relaxation and creep, respectively. We hypothesized that in the rabbit MCL the rate of stress relaxation would be strain dependent and the rate of creep would be stress dependent. Thirty MCLs from 15 rabbits were tested ex vivo for this study. Results show that within the physiologically relevant region of ligament behavior, the rate of stress relaxation is strain dependent in the rabbit MCL, with the rate of relaxation decreasing with increasing tissue strain. The rate of creep is stress dependent in the rabbit MCL, with the rate of creep decreasing with increasing stress. These results support our hypothesis, with the greatest nonlinearities in a physiologically relevant region of loading. As such, these nonlinearities should be considered when quantifying ligament viscoelastic behavior with a rabbit model.
Orthopedic Research Laboratories, Department of Orthopedics and Rehabilitation, University of Wisconsin, Madison, Wisconsin 53792, USA.
Rittu V
RV
Hingorani
Paolo P
PP
Provenzano
Roderic S
RS
Lakes
Anthony
A
Escarcega
Ray
R
Vanderby
D000818:Animals; D003198:Computer Simulation; D046508:Culture Techniques; D004548:Elasticity; D017888:Medial Collateral Ligament, Knee / Q000502:physiology*; D008954:Models, Biological; D017711:Nonlinear Dynamics; D010812:Physical Stimulation / Q000379:methods*; D011817:Rabbits; D013314:Stress, Mechanical; D014783:Viscosity