[Increase of TNF-alpha in subjects occupationally exposed to lead].
Occupational exposure at low doses of lead induces a significant increase of TNF-alpha plasma levels. Recently has been showed the crucial role on atherosclerosis origin of this pro-inflammatory cytokine. It is assumable a contribution of lead in atherosclerosis course in exposed subjects.
Santarelli
L
L
Clinica di Medicina del Lavoro Università Politecnica delle Marche, Ancona.
Valentino
M
M
Bracci
M
M
Rapisarda
V
V
Mocchegiani
E
E
Cassano
F
F
Di Lorenzo
L
L
Soleo
L
L
D000328:Adult; D006801:Humans; D007854:Lead / Q000633:toxicity*; D016273:Occupational Exposure / Q000009:adverse effects*; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis*
D014409:Tumor Necrosis Factor-alpha; D007854:Lead