99mTc-Depreotide chest SPECT demonstrates pulmonary metastases from renal cell carcinoma.
99mTc-Depreotide has been used on single pulmonary nodules to identify somatostatin receptor-positive lung cancer. We report that pulmonary metastases of a 78-y-old man with postradical nephrectomy for renal cell carcinoma were detected by (99m)Tc-depreotide chest SPECT. Thus, (99m)Tc-depreotide chest SPECT can be used to diagnose secondary lung cancer, such as pulmonary metastases from renal cell carcinoma with somatostatin receptor-positive tumor, other than primary lung cancer. Depending on whether the (99m)Tc-depreotide was positive for pulmonary metastases, the patient underwent an appropriate therapy without further invasive procedures.
Nuclear Medicine Service, VA Medical Center, Lexington, Kentucky, USA. wshih0@uky.edu
Wei-Jen
WJ
Shih
Ramon A L
RA
Romero
Mullet
M
Timothy
Primo P
PP
Milan
D000368:Aged; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging* / Q000556:secondary*; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D008297:Male; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D013004:Somatostatin / Q000031:analogs & derivatives*; D015899:Tomography, Emission-Computed, Single-Photon
D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D013004:Somatostatin; C444119:technetium Tc 99m depreotide