[A case of endobronchial mucormycosis with peculiar bronchoscopic findings].
Small cell lung cancer was diagnosed in a 54-year-old man in 1997. He had received 5 cycles of systemic chemotherapy and thoracic irradiation since 1997, and a favorable response had been achieved. In August 2001, pro-GRP was again elevated, and he was readmitted. Bronchoscopic findings revealed a white dendritic endobronchial mass on a cheese-like plug obstructing the left upper bronchus division. Numerous mucor hyphe and cancer cells were detected by transbronchial biopsy, and a fungal culture disclosed mucor. Although no antifungal drug was administered, the bronchial lesion disappeared after removal with biopsy forceps and 2 cycles of systemic anticancer chemotherapy. Endobronchial involvement of mucormycosis is rare and this case is unique because of the peculiar bronchoscopic finding with the endobronchial lesion.
Tomita
Shougo
S
Dept. of Respiratory Medicine, Fujigaoka Hospital of Showa University School of Medicine, Fujigaoka 1-30, Aobaku, Yokohama 227-8501.
Takeda
Norikazu
N
Hasumoto
Makoto
M
Kagiyama
Nao
N
Yano
Ryouzou
R
Nakamura
Takayuki
T
Kijima
Hirotake
H
Iwaku
Fumiko
F
Kuraishi
Hiroshi
H
Kikuchi
Toshiki
T
Otsuka
Hidehiko
H
Narushima
Michiaki
M
Suzuki
Hajime
H
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy / Q000379:methods; D001982:Bronchial Diseases / Q000209:etiology* / Q000473:pathology* / Q000628:therapy; D001999:Bronchoscopy; D018288:Carcinoma, Small Cell / Q000150:complications* / Q000628:therapy; D002945:Cisplatin / Q000008:administration & dosage; D006801:Humans; D016867:Immunocompromised Host; D008175:Lung Neoplasms / Q000150:complications* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000209:etiology* / Q000473:pathology* / Q000628:therapy; D017239:Paclitaxel / Q000008:administration & dosage; D020103:Rhizomucor; D013525:Surgical Instruments; D016896:Treatment Outcome
D017239:Paclitaxel; D002945:Cisplatin