Microtubule depolymerization by vincristine causes cell death after transition from C mitosis to interphase.
Novichkova
E A
EA
Moscow State University, Vorob'evy gory, Moscow, 119899 Russia.
Onishchenko
G E
GE
Shtil
A A
AA
D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology; D017209:Apoptosis; D016923:Cell Death; D045744:Cell Line, Tumor; D002467:Cell Nucleus / Q000648:ultrastructure; D002843:Chromatin / Q000378:metabolism; D004396:Coloring Agents / Q000494:pharmacology; D003599:Cytoskeleton / Q000378:metabolism; D005434:Flow Cytometry; D006056:Golgi Apparatus / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D007399:Interphase; D008870:Microtubules / Q000737:chemistry* / Q000648:ultrastructure; D008938:Mitosis; D011003:Ploidies; D013778:Tetrazolium Salts / Q000494:pharmacology; D013844:Thiazoles / Q000494:pharmacology; D013997:Time Factors; D014750:Vincristine / Q000494:pharmacology*
D000972:Antineoplastic Agents, Phytogenic; D002843:Chromatin; D004396:Coloring Agents; D013778:Tetrazolium Salts; D013844:Thiazoles; D014750:Vincristine; C022616:thiazolyl blue