[Increase of TNF-alpha in subjects occupationally exposed to lead].
Occupational exposure at low doses of lead induces a significant increase of TNF-alpha plasma levels. Recently has been showed the crucial role on atherosclerosis origin of this pro-inflammatory cytokine. It is assumable a contribution of lead in atherosclerosis course in exposed subjects.
Clinica di Medicina del Lavoro Università Politecnica delle Marche, Ancona.
L
L
Santarelli
M
M
Valentino
M
M
Bracci
V
V
Rapisarda
E
E
Mocchegiani
F
F
Cassano
L
L
Di Lorenzo
L
L
Soleo
D000328:Adult; D006801:Humans; D007854:Lead / Q000633:toxicity*; D016273:Occupational Exposure / Q000009:adverse effects*; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis*
D014409:Tumor Necrosis Factor-alpha; D007854:Lead