General anesthesia of infant mice by isoflurane inhalation for medium-duration surgery.
In this report we describe a means of general anesthesia for medium-duration (i.e., 20 to 60 min) surgery of infant mice. We tested isoflurane inhalation (2.0% isoflurane in air or oxygen during induction, and 1.5% after surgical anesthesia) anesthesia of 6-to 10-day-old C57BL/6JJcl mice and obtained safe, effective, and reproducible results.
Model Animals Laboratory, Molecular Biology and Immunology Department, National Institute of Agrobiological Sciences, Kannondai, Tsukuba, Ibaraki, Japan.
Hideo
H
Gotoh
Yukiko
Y
Matsumoto
Kenkichi
K
Imamura
D000768:Anesthesia, General / Q000662:veterinary*; D018685:Anesthetics, Inhalation / Q000008:administration & dosage*; D000818:Animals; D000831:Animals, Newborn; D007530:Isoflurane / Q000008:administration & dosage*; D051379:Mice; D010100:Oxygen
D018685:Anesthetics, Inhalation; D007530:Isoflurane; D010100:Oxygen