[Plasma lipid profile and lipid peroxidation in overweight or obese children and adolescents].
OBJECTIVE
To study the plasma lipid profile and lipid peroxidation in overweight or obese children and adolescents receiving care at the pediatric endocrinology clinic in HOSPED/UFRN, a university hospital.


METHODS
Three groups were studied: overweight (n = 15), obese (n = 30) and control (n = 21) children and adolescents. To evaluate plasma lipid profile, total cholesterol, LDL-cholesterol, HDL-cholesterol and triglyceride levels were measured. Lipid peroxidation was determined by measuring malondialdehyde concentration. Data were analyzed using Student's t test, Tukey test, ANOVA and Pearson's correlation.


RESULTS
Altered levels of total and LDL-cholesterol were observed mainly in overweight or obese males. HDL-cholesterol was borderline in the overweight and obese groups of both sexes. Obese females had the highest levels of triglycerides. Increased plasma lipid peroxidation was observed mainly in obese males.


CONCLUSIONS
In the present population, the greatest alterations in lipid profile were observed in obese and overweight males. Plasma lipid peroxidation was more evident in obese males and females.
Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN, Brazil. scarla@samnet.com.br
Severina C V C
SC
Lima
Ricardo F
RF
Arrais
Maria G
MG
Almeida
Zélia M
ZM
Souza
Lúcia F C
LF
Pedrosa
D000293:Adolescent; D015992:Body Mass Index; D001835:Body Weight; D016022:Case-Control Studies; D002648:Child; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation; D008055:Lipids / Q000097:blood*; D008297:Male; D009765:Obesity / Q000097:blood* / Q000378:metabolism; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol