Application of the mouse exo utero development system in the study of developmental biology and teratology.
The mouse exo utero development system is useful for analyzing the roles of molecules or interactions between tissues in the histogenesis of organs after the mid-gestational period. In the article presented here, we review the mouse exo utero development system and its specific modifications depending on different purposes as well as its advantages over and limitations compared to other systems in the study of developmental biology and teratology.
Department of Anatomy, Faculty of Medicine, Shimane University, Izumo, Japan. thatta@med.shimane-u.ac.jp
Toshihisa
T
Hatta
Akihiro
A
Matsumoto
Hiroki
H
Otani
D000818:Animals; D002540:Cerebral Cortex / Q000196:embryology / Q000502:physiology; D015509:Developmental Biology / Q000379:methods*; D033041:Embryo Research; D005121:Extremities / Q000196:embryology / Q000502:physiology; D005260:Female; D047109:Fetal Development / Q000502:physiology; D016222:Fibroblast Growth Factor 2 / Q000378:metabolism; D008297:Male; D051379:Mice; D018600:Teratology / Q000379:methods*
D016222:Fibroblast Growth Factor 2