The c-SRC1 gene visualized by in situ hybridization on Xenopus laevis chromosomes.
Fluorescent in situ hybridization followed by tyramide signal amplification was used to map the site of the c-SRC1 gene on XENOPUS LAEVIS chromosomes. Positive results were obtained with a cDNA probe of about 1 kb. The c-SRC1 gene is located in the subcentromeric region in the long arm of one of the acrocentric chromosomes of the G category (classified according to Graf and Kobel, 1991). The c-SRC1 gene and the XENOPUS major histocompatibility complex (MHC) 1b locus, which consists of 20 tandemly arranged gene copies, are situated on different chromosomes of the G category.
Department of Physiology and Developmental Biology, Faculty of Science, Charles University, Prague, Czech Republic.
V
V
Krylov
J
J
Mácha
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T
Tlapáková
M
M
Takác
J
J
Jonák
D000818:Animals; D030801:Animals, Genetically Modified; D002874:Chromosome Mapping; D016391:Genes, src; D017404:In Situ Hybridization, Fluorescence; D016392:Proto-Oncogene Proteins pp60(c-src) / Q000235:genetics*; D029867:Xenopus Proteins / Q000235:genetics*; D014982:Xenopus laevis / Q000235:genetics*
D029867:Xenopus Proteins; D016392:Proto-Oncogene Proteins pp60(c-src)