Behçet's disease with relapsing cutaneous polyarteritis-nodosa-like lesions, responsive to oral cyclosporine therapy.
Cutaneous polyarteritis-nodosa-like lesions are rarely described in Behcet's disease. We report a case of recurrent cutaneous polyarteritis-nodosa-like (C-PAN-like) lesions in Behcet's disease with multiple deep vein thromboses as part of systemic vasculitis. The mucocutaneous manifestations responded to prednisolone; however, C-PAN-like lesions were refractory and responded to oral cyclosporine. We conclude that C-PAN-like lesions may be marker of severe disease and require intense immunosuppressive therapy.
Vikas
Agarwal
A
Department of General Medicine and Pathology, Government Medical College and Hospital, Chandigarh, India. vikasagr@yahoo.com
Atul
Sachdev
S
Singh
R
R
Sarbmeet
Lehl
L
Mohan
Harsh
H
D000293:Adolescent; D000925:Anticoagulants / Q000627:therapeutic use; D001379:Azathioprine / Q000627:therapeutic use; D001528:Behcet Syndrome / Q000150:complications* / Q000188:drug therapy; D003078:Colchicine / Q000627:therapeutic use; D016572:Cyclosporine / Q000627:therapeutic use*; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D010488:Polyarteritis Nodosa / Q000150:complications* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D013924:Thrombophlebitis / Q000209:etiology; D014859:Warfarin / Q000627:therapeutic use
D000925:Anticoagulants; D007166:Immunosuppressive Agents; D014859:Warfarin; D016572:Cyclosporine; D006493:Heparin; D001379:Azathioprine; D003078:Colchicine; D011241:Prednisone; D008727:Methotrexate