[The analysis of histopathology of conjunctivochalasis].
OBJECTIVE
To observe the histopathological change of conjunctivochalasis.


METHODS
Conjunctival tissue was collected from 17 patients with conjunctivochalasis and 15 simple cataract patients. By HE/Verhoeff elastic fiber staining, the histopathological changes of conjunctival tissues in the patients were compared with those of simple cataract patients.


RESULTS
The pathologic changes in conjunctivochalasis patients were characterized with hyperplasia of squamous epithelium with parakeratosis, pigmentation with different level in basal cell, hemorrhage, edema of stroma, infiltration of lymphocyte and plasmocyte. The elastic fiber layer was decreased.


CONCLUSIONS
There was hyperplasia of conjunctival epithelium, decrease of elastic fiber and chronic inflammation in patients with conjunctivochalasis. The decrease of elastic fiber should be considered as major cause of the changes of conjunctiva.
Zhang
Xing-ru
XR
Department of Ophthalmology, Affiliated Pu-tuo Hospital to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China. zhangxingru@china.com
Cai
Rui-xia
RX
Wang
Bao-hua
BH
Li
Qing-song
QS
Liu
Ye-xiang
YX
Xu
Yan
Y
D000368:Aged; D003229:Conjunctival Diseases / Q000473:pathology*; D005141:Eyelid Diseases / Q000473:pathology; D005143:Eyelids / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000473:pathology