Recurrent subependymoma treated with radiosurgery.
OBJECTIVE
Subependymomas are rare, slow-growing intracranial neoplasms of the subependymal matrix. We document a successful case of radiosurgical treatment of a multiply recurrent subependymoma.


METHODS
A nineteen-year-old male developed a recurrent fourth ventricular subependymoma after 6 resections, fractionated radiation therapy (50.4 Gy) and chemotherapy. In addition, a lesion consistent with a cavernous malformation (CM) was noted adjacent to the tumor within the previously irradiated region.


RESULTS
Stereotactic radiosurgery was performed covering both the subependymoma and the presumed CM. Fifty-four months after radiosurgery, both lesions had decreased in size and the patient remained neurologically unchanged.


CONCLUSIONS
Subependymoma may be added to the list of primary glial neoplasms that have been successfully managed with stereotactic radiosurgery. Also, we add a case of presumed CM following radiation therapy to the literature.
Department of Neurological Surgery, Mayo Clinic and Foundation, Rochester, MN, USA.
Robert D
RD
Ecker
Bruce E
BE
Pollock
D000328:Adult; D001932:Brain Neoplasms / Q000601:surgery*; D018315:Glioma, Subependymal / Q000601:surgery*; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D016634:Radiosurgery / Q000379:methods*