[A case of endobronchial mucormycosis with peculiar bronchoscopic findings].
Small cell lung cancer was diagnosed in a 54-year-old man in 1997. He had received 5 cycles of systemic chemotherapy and thoracic irradiation since 1997, and a favorable response had been achieved. In August 2001, pro-GRP was again elevated, and he was readmitted. Bronchoscopic findings revealed a white dendritic endobronchial mass on a cheese-like plug obstructing the left upper bronchus division. Numerous mucor hyphe and cancer cells were detected by transbronchial biopsy, and a fungal culture disclosed mucor. Although no antifungal drug was administered, the bronchial lesion disappeared after removal with biopsy forceps and 2 cycles of systemic anticancer chemotherapy. Endobronchial involvement of mucormycosis is rare and this case is unique because of the peculiar bronchoscopic finding with the endobronchial lesion.
Dept. of Respiratory Medicine, Fujigaoka Hospital of Showa University School of Medicine, Fujigaoka 1-30, Aobaku, Yokohama 227-8501.
Shougo
S
Tomita
Norikazu
N
Takeda
Makoto
M
Hasumoto
Nao
N
Kagiyama
Ryouzou
R
Yano
Takayuki
T
Nakamura
Hirotake
H
Kijima
Fumiko
F
Iwaku
Hiroshi
H
Kuraishi
Toshiki
T
Kikuchi
Hidehiko
H
Otsuka
Michiaki
M
Narushima
Hajime
H
Suzuki
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy / Q000379:methods; D001982:Bronchial Diseases / Q000209:etiology* / Q000473:pathology* / Q000628:therapy; D001999:Bronchoscopy; D018288:Carcinoma, Small Cell / Q000150:complications* / Q000628:therapy; D002945:Cisplatin / Q000008:administration & dosage; D006801:Humans; D016867:Immunocompromised Host; D008175:Lung Neoplasms / Q000150:complications* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000209:etiology* / Q000473:pathology* / Q000628:therapy; D017239:Paclitaxel / Q000008:administration & dosage; D020103:Rhizomucor; D013525:Surgical Instruments; D016896:Treatment Outcome
D017239:Paclitaxel; D002945:Cisplatin