Motor overflow in schizophrenia.
The occurrence of motor dysfunction as a sign of schizophrenia, in addition to being a side effect of medication, has received considerable support in recent years. The current study aimed to systematically investigate both the presence and pattern of one such motor dysfunction, motor overflow. It was hypothesised that patients with schizophrenia would show significantly greater motor overflow than controls, and that the pattern of motor overflow occurrence would also vary significantly between the groups. A finger flexion task was used to examine the presence and pattern of motor overflow. Subjects were asked to maintain target forces, using either their index or small finger, representing 25, 50 or 75% of the maximum strength capacity for whichever finger was performing the task. Patients were found to exhibit significantly greater motor overflow than controls. There were also significant findings with respect to the patterns of motor overflow produced, specifically in regards to fine motor control and performance variability. In summary, patients differed significantly from controls in both the degree and pattern of overflow exhibited.
Hoy
Kate E
KE
Experimental Neuropsychology Research Unit, Psychology Department, Monash University, Clayton 3800, Victoria, Australia. Kate.Hoy@med.monash.edu.au
Fitzgerald
Paul B
PB
Bradshaw
John L
JL
Farrow
Maree
M
Brown
Timothy L
TL
Armatas
Christine A
CA
Georgiou-Karistianis
Nellie
N
D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006225:Hand / Q000503:physiopathology; D006801:Humans; D008297:Male; D011596:Psychomotor Disorders / Q000453:epidemiology* / Q000503:physiopathology; D012559:Schizophrenia / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D011795:Surveys and Questionnaires
D014150:Antipsychotic Agents