[Role of the structural changes of lungs in thanatogenesis of cranio-cerebral complicated trauma].
The lungs of 27 persons, who died of severe craniocerebral and combined trauma, were histologically examined. A deformation of the bronchi is registered in 15-60 min after craniocerebral trauma; desquamated epithelium and mucinous contents are found in their lumens. Erythrocytes and macrophages are detected in the alveolar lumens. The capillary alveolar septums are full-blooded; the alveolar septums are edematous with signs of hemorrhages and clusters of lymphoid cells. The venules are enlarged and full-blooded. Regions of the emphysema alternate with dystelectases and atelectases. The interstitial edema set on and the alveolar edema aggravates in 2-8 hours after trauma. There is an aggregation of erythrocytes. The leukocytic infiltration worsens. Hyaline membranes take shape. Similar changes are observed in the lungs in case of combined trauma; at the same time, the morphological changes are faster in the latter trauma variation. The detected structural impairments are typical of an acute pulmonary lesion and are crucial in thanatogenesis in craniocerebral and combined trauma.
Golubev
A M
AM
Sundukov
D V
DV
D000328:Adult; D006259:Craniocerebral Trauma / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D008168:Lung / Q000098:blood supply / Q000473:pathology*; D008875:Middle Aged; D009104:Multiple Trauma / Q000473:pathology* / Q000503:physiopathology; D011180:Postmortem Changes; D011652:Pulmonary Circulation / Q000502:physiology