Antifungal activities of four fatty acids against plant pathogenic fungi.
The effect of the fatty acids linolenic acid, linoleic acid, erucic acid and oleic acid on the growth of the plant pathogenic fungi Rhizoctonia solani, Pythium ultimum, Pyrenophora avenae and Crinipellis perniciosa were examined in in vitro studies. Linolenic and linoleic acids exhibited activity against all of the fungi. However, whereas linolenic acid reduced mycelial growth of R. solani and C. perniciosa at 100 microM, the concentration had to be increased to 1000 microM before any effect on mycelial growth of P. ultimum and P. avenae was observed. Linoleic acid only reduced mycelial growth of R. solani, P. ultimum and P. avenae at 1000 microM, but led to a significant reduction in growth of C. perniciosa at 100 microM. In contrast, oleic acid had no significant effect on growth of R. solani or P. avenae, but gave significant reductions in mycelial growth of P. ultimum at 100 microM and reduced growth of C. perniciosa significantly at 1000 microM. All of the fatty acids reduced biomass production by all of the fungi significantly in liquid culture when added to the media at 100 microM. Erucic acid had no effect on fungal growth at any concentration examined. The antifungal activities exhibited by linolenic, linoleic and oleic acids may be useful in the search for alternative approaches to controlling important plant pathogens, such as those examined in this study.
Department of Plant Biology, Scottish Agricultural College, Ayr Campus, Auchincruive Estate, Ayr KA6 5HW, UK. d.walters@au.sac.ac.uk
Dale
D
Walters
Lynda
L
Raynor
Anne
A
Mitchell
Robin
R
Walker
Kerr
K
Walker
D001203:Ascomycota / Q000187:drug effects* / Q000254:growth & development; D001487:Basidiomycota / Q000187:drug effects* / Q000254:growth & development; D004883:Erucic Acids / Q000494:pharmacology; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology*; D019787:Linoleic Acid / Q000494:pharmacology; D019301:Oleic Acid / Q000494:pharmacology; D010935:Plant Diseases / Q000382:microbiology*; D011775:Pythium / Q000187:drug effects* / Q000254:growth & development; D012232:Rhizoctonia / Q000187:drug effects* / Q000254:growth & development; D017962:alpha-Linolenic Acid / Q000494:pharmacology
D004883:Erucic Acids; D005231:Fatty Acids, Unsaturated; C049811:erucic acid; D017962:alpha-Linolenic Acid; D019301:Oleic Acid; D019787:Linoleic Acid