Evaluation of hearing and auditory nerve function by combining ABR, DPOAE and eABR tests into a single recording session.
In this article, we describe an efficient method for testing both auditory receptor and auditory nerve function in a single recording session. Auditory receptor function is tested in response to pure tone, tone burst and click acoustic stimuli (i.e. distortion products of otoacoustic emissions, DPOAE; and auditory-evoked brainstem responses, ABR). The function of the auditory neurons and nerve is measured in response to direct electric current stimulation (i.e. electrically evoked auditory brainstem responses, eABR). All measurements were obtained from anesthetized laboratory rats during single recording sessions using hardware and software stimulation and analysis programs developed by Intelligent Hearing Systems, Miami, FL.
Department of Otolaryngology, Cochlear Implant Research Program, University of Miami Ear Institute, 1600 NW 10th Avenue, RMSB 3160, Miami, FL 33136, USA.
Marek
M
Polak
Adrien A
AA
Eshraghi
Omar
O
Nehme
Syed
S
Ahsan
Jose
J
Guzman
Rafael E
RE
Delgado
Jiao
J
He
Fred F
FF
Telischi
Thomas J
TJ
Balkany
Thomas R
TR
Van De Water
D000161:Acoustic Stimulation / Q000379:methods; D000818:Animals; D001307:Auditory Perception / Q000502:physiology*; D001309:Auditory Threshold / Q000502:physiology / Q000528:radiation effects; D003056:Cochlear Nerve / Q000502:physiology*; D004307:Dose-Response Relationship, Radiation; D004558:Electric Stimulation / Q000379:methods; D004566:Electrodes; D005072:Evoked Potentials, Auditory / Q000502:physiology* / Q000528:radiation effects; D006309:Hearing / Q000502:physiology*; D006320:Hearing Tests / Q000379:methods*; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology* / Q000528:radiation effects; D051381:Rats; D011916:Rats, Inbred F344