A convenient procedure for bismuth-mediated Barbier-type allylation of aldehydes in water containing fluoride ions.
A new and convenient procedure for synthesis of homoallylic alcohols in generally good to excellent yields has been developed. The bismuth-mediated Barbier-type allylation of aldehydes (aromatic, aliphatic, alicyclic and heterocyclic) with allyl bromide has been carried out smoothly in water in the presence of fluoride ions.
Smith
Keith
K
Centre for Clean Chemistry, Department of Chemistry, University of Wales Swansea, Singleton Park, Swansea, UK SA2 8PP.
Lock
Sandra
S
El-Hiti
Gamal A
GA
Wada
Makoto
M
Miyoshi
Norikazu
N