[Red blood cell system in albino rats exposed to long-term nitrite intoxication].
The long-term intake of nitrates at a concentration of 0.2 g/l in animals affects erythrocytic parameters. The nature of this effect depends on the duration of intoxication. There are three-phase changes in the concentrations of red blood cells and hemoglobin, which accompany the substantial changes of the functional characteristics of erythrocytic membranes. The intensification of erythropoiesis developing under such conditions is based on erythroidal hyperplasia of the red bone marrow and spleen and it is of compensatory significance, by ensuring the recovery of the parameters of the erythrocytic composition by the end of the experiment.
Ivanova
A S
AS
Pakhrova
O A
OA
Nazarov
S B
SB
D000818:Animals; D004912:Erythrocytes / Q000378:metabolism*; D004920:Erythropoiesis / Q000187:drug effects; D005260:Female; D009573:Nitrites / Q000097:blood* / Q000633:toxicity*; D051381:Rats; D013997:Time Factors
D009573:Nitrites