Formins coming into focus.
Two new crystal structures published in Cell and Molecular Cell provide the first clues about how fascinating proteins called formins interact with actin filaments.
Pollard
Thomas D
TD
Departments of Molecular, Cellular & Developmental Biology, Cell Biology, and Molecular Biophysics & Biochemistry, Yale University, New Haven, CT 06520, USA.
D008841:Actin Cytoskeleton / Q000378:metabolism*; D000818:Animals; D005326:Fetal Proteins / Q000737:chemistry* / Q000378:metabolism; D000080865:Formins; D005656:Fungal Proteins / Q000737:chemistry; D008840:Microfilament Proteins; D008958:Models, Molecular; D009687:Nuclear Proteins / Q000737:chemistry* / Q000378:metabolism; D011485:Protein Binding; D017434:Protein Structure, Tertiary / Q000502:physiology; D015003:Yeasts / Q000737:chemistry
D005326:Fetal Proteins; D000080865:Formins; D005656:Fungal Proteins; D008840:Microfilament Proteins; D009687:Nuclear Proteins