Structure of human translin at 2.2 A resolution.
The structure of human translin at 2.2 A resolution is reported in space group C222(1). Translin forms a tetramer in the asymmetric unit. Although the monomer structure is almost the same as the crystal structure of murine translin in space group P2(1)2(1)2, the relative positions of the tetramers differ between the human and murine translins. This suggests that the multimerization of translin is flexible; the flexibility may be related to the binding to DNA/RNA.
Sugiura
Ikuko
I
ZoeGene, 1000 Kamoshida, Aobaku, Yokohama 227-8502, Japan.
Sasaki
Chiduko
C
Hasegawa
Tsukasa
T
Kohno
Toshiyuki
T
Sugio
Shigetoshi
S
Moriyama
Hideaki
H
Kasai
Masataka
M
Matsuzaki
Takao
T
D003460:Crystallization; D018360:Crystallography, X-Ray; D004268:DNA-Binding Proteins / Q000737:chemistry*; D019281:Dimerization; D006801:Humans; D008958:Models, Molecular; D015394:Molecular Structure; D011487:Protein Conformation
D004268:DNA-Binding Proteins; C095563:TSN protein, human