Pemphigus: current therapy.
Pemphigus is an autoimmune skin disease that can present in a variety of forms and can be a challenging disease to manage and treat. An overview of the different forms of pemphigus and diagnostics are discussed including pemphigus foliaceus (PF), pemphigus erythematosus (PE), panepidermal pustular pemphigus (PPP), pemphigus vulgaris (PV) and paraneoplastic pemphigus (PNP). Emphasis on therapy is presented. Included are the most current commonly used therapeutics (glucocorticoids, azathioprine, chlorambucil and tetracycline and niacinamide); current alternative therapeutics (cyclosporin and tacrolimus and mycophenolate mofetil) and additional alternative therapeutics (cyclophosphamide, chrysotherapy, dapsone, sulfasalazine and intravenous immunoglobulin (IVIG) therapy).
Rosenkrantz
Wayne S
WS
Animal Dermatology Clinic, Tustin, CA 92780, USA. AnDerm1@aol.com
D000818:Animals; D018501:Antirheumatic Agents / Q000008:administration & dosage; D001379:Azathioprine / Q000008:administration & dosage; D002699:Chlorambucil / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage; D016572:Cyclosporine / Q000008:administration & dosage; D003622:Dapsone / Q000008:administration & dosage; D004283:Dog Diseases / Q000175:diagnosis* / Q000188:drug therapy*; D004285:Dogs; D005938:Glucocorticoids / Q000008:administration & dosage; D016756:Immunoglobulins, Intravenous; D009173:Mycophenolic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives*; D009536:Niacinamide / Q000008:administration & dosage; D050607:Organogold Compounds; D010392:Pemphigus / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D012460:Sulfasalazine / Q000008:administration & dosage; D016559:Tacrolimus / Q000008:administration & dosage; D013752:Tetracycline / Q000008:administration & dosage
D018501:Antirheumatic Agents; D005938:Glucocorticoids; D016756:Immunoglobulins, Intravenous; D050607:Organogold Compounds; D002699:Chlorambucil; D009536:Niacinamide; D012460:Sulfasalazine; D016572:Cyclosporine; D003520:Cyclophosphamide; D003622:Dapsone; D013752:Tetracycline; D009173:Mycophenolic Acid; D001379:Azathioprine; D016559:Tacrolimus