Lipid metabolism: ceramide transfer protein adds a new dimension.
Just as non-lipidologists were becoming reconciled to the complexities of networks of ceramide metabolism and the diverse roles of ceramide in cell regulation and membrane structure, a new study reveals a new layer of regulation of ceramide through the actions of a ceramide binding/transfer protein.
Hannun
Yusuf A
YA
Department of Biochemistry and Molecular Biology, Medical University of South Carolina, 173 Ashley Ave, Charleston, South Carolina 29425, USA. hannun@musc.edu
Luberto
Chiara
C
D002518:Ceramides / Q000378:metabolism*; D050356:Lipid Metabolism; D008958:Models, Molecular; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D015398:Signal Transduction; D013107:Sphingolipids / Q000378:metabolism
D002518:Ceramides; D013107:Sphingolipids; C119090:CERT1 protein, human; D017346:Protein Serine-Threonine Kinases