title: Unusual skeletal metastases from myxoid liposarcoma only detectable by MR imaging.
abstract: We present two cases of skeletal metastases from myxoid liposarcoma, occurring several years after treatment of the primary tumors in the lower limb. The present two case reports have unusual radiological features only detectable by MR imaging and not by plain radiographs or bone scans. From the present two cases, we found that a negative plain radiograph of the spine or a negative bone scan could not exclude skeletal metastases from myxoid liposarcoma, and MRI was a more sensitive screening procedure for their detection, especially in T1-weighted images. Unusual radiological features of skeletal metastases from myxoid liposarcoma are not well documented and only a few cases have been previously reported. Our aim is to document two more patients exhibiting the unusual radiological features of skeletal metastases from myxoid liposarcoma to improve their early detection and management.
authors.affiliation: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamada-Oka, Suita, 565-0871 Osaka, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Ishii
authors.forename: Takafumi
authors.initials: T
authors.lastname: Ueda
authors.forename: Akira
authors.initials: A
authors.lastname: Myoui
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Tamai
authors.forename: Noboru
authors.initials: N
authors.lastname: Hosono
authors.forename: Hideki
authors.initials: H
authors.lastname: Yoshikawa
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D003131:Combined Modality Therapy; D003287:Contrast Media / Q000494:pharmacology; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D018208:Liposarcoma, Myxoid / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D035002:Lower Extremity; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009367:Neoplasm Staging; D018570:Risk Assessment; D012983:Soft Tissue Neoplasms / Q000473:pathology* / Q000628:therapy; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media