title: [Analysis of anthraquinones in serum and urine after oral administration of semen Cassiae].
abstract: OBJECTIVE
  To analysie the anthraquinones absorbed into serum by different animals (or human beings) after oral administration of Semen Cassiae.
  
  
  METHODS
  Anthraquinones in serum and urine of rats and urine of healthy men after taking Semen Cassiae orally were detected with HPLC.
  
  
  RESULTS
  Only some of the anthraquinones were absorbed into serum. There were differences in absorption and metabolism of anthraquinones between rats and men and some new anthraquinones were produced in the process.
  
  
  CONCLUSIONS
  Anthraquinones absorbed into serum by the experimental animals or men should become target for researching into active compounds of anthraquinones in Semen Cassiae.
authors.affiliation: College of Life Science of South China Normal University, Guangzhou 510631, Guangdong, China. lixue@scnu.edu.cn
authors.forename: Xu-e
authors.initials: XE
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Ma
authors.forename: Bao-jiang
authors.initials: BJ
authors.lastname: Guo
authors.forename: Zhi
authors.initials: Z
authors.lastname: Zeng
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000880:Anthraquinones / Q000097:blood* / Q000652:urine; D002366:Cassia / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000302:isolation & purification / Q000493:pharmacokinetics*; D006801:Humans; D008297:Male; D010946:Plants, Medicinal / Q000737:chemistry; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D012639:Seeds / Q000737:chemistry; D013045:Species Specificity
chemical_list: D000880:Anthraquinones; D004365:Drugs, Chinese Herbal