title: Malignant peripheral nerve sheath tumor arising from an adrenal ganglioneuroma in a 6-year-old boy.
abstract: This report describes the youngest patient to develop a malignant peripheral nerve sheath tumor arising from a ganglioneuroma (MPNST ex Ganglioneuroma). The patient, a 6-year-old boy, was never irradiated and had no history or stigmata of neurofibromatosis. The report also includes a review of the previously published related cases, and an analysis of the immunohistochemistry and electron microscopy data available to date on the subject.
authors.affiliation: Department of Pathology and Laboratory Medicine, St. Christopher's Hospital for Children, and Drexel University College of Medicine, Philadelphia, PA 19134, USA. jd37@drexel.edu
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: de Chadarévian
authors.forename: Judy
authors.initials: J
authors.lastname: MaePascasio
authors.forename: Gregory E
authors.initials: GE
authors.lastname: Halligan
authors.forename: Douglas A
authors.initials: DA
authors.lastname: Katz
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Locono
authors.forename: Stephen
authors.initials: S
authors.lastname: Kimmel
authors.forename: Christos D
authors.initials: CD
authors.lastname: Katsetos
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000473:pathology* / Q000628:therapy / Q000652:urine; D000315:Adrenalectomy; D000971:Antineoplastic Combined Chemotherapy Protocols; D002648:Child; D005729:Ganglioneuroma / Q000473:pathology* / Q000628:therapy / Q000652:urine; D006719:Homovanillic Acid / Q000652:urine; D006801:Humans; D008297:Male; D018317:Nerve Sheath Neoplasms / Q000473:pathology* / Q000628:therapy / Q000652:urine; D014642:Vanilmandelic Acid / Q000652:urine
chemical_list: D014642:Vanilmandelic Acid; D006719:Homovanillic Acid