title: Native aortic valve vegetative endocarditis with Cunninghamella.
abstract: Cunninghamella bertholletiae is a rare Mucor species that is seldom the cause for endocarditis of prosthetic heart valves. It is even a more uncommon cause of endocarditis of native heart valves. We present a case of Cunninghamella endocarditis of a native aortic valve in an immuno-compromised patient, diagnosed from tissue culture obtained at the time of surgery. There have only been two other reported cases of native valve endocarditis with a Mucor species, and in those cases, the diagnoses were made post-mortem.
authors.affiliation: Hospital of the University of Pennsylvania, 3400 Spruce Street, 9 Gates Pavilion, Philadelphia, PA 19103, USA.
authors.forename: Nehal Nikhilesh
authors.initials: NN
authors.lastname: Mehta
authors.forename: Jeanine
authors.initials: J
authors.lastname: Romanelli
authors.forename: Martin Graham St John
authors.initials: MG
authors.lastname: Sutton
mesh_terms: D000328:Adult; D001011:Aorta / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000601:surgery; D001022:Aortic Valve Insufficiency / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery; D020093:Cunninghamella; D018450:Disease Progression; D004452:Echocardiography; D017548:Echocardiography, Transesophageal; D004562:Electrocardiography; D004696:Endocarditis / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D006333:Heart Failure / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery; D009091:Mucormycosis / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D014057:Tomography, X-Ray Computed