title: [Tourette syndrome: an analysis of its comorbidity and specific treatment].
abstract: METHODS
  Tic disorders can be severe enough to be incapacitating, but in most cases the observation of tics should alert the clinician to the possible presence of other conditions that may be more impairing even if less directly observable. The comorbid diagnoses that are best documented are obsessive compulsive disorder and attention deficit/hyperactivity disorder (ADHD).
  
  
  CONCLUSIONS
  Treatment of Tourette syndrome combined with ADHD is often challenging. Alpha 2 agonists, such as guanfacine, or non stimulant options such as atomoxetine, where available, are worth considering, although many individuals with Tourette syndrome and ADHD can be successfully treated with judicious doses of stimulant medications.
authors.affiliation: Institute of Pediatric Neuroscience, NYU Child Study Center, New York NY 10016-6404, USA.
authors.forename: F X
authors.initials: FX
authors.lastname: Castellanos
authors.forename: M T
authors.initials: MT
authors.lastname: Acosta
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000627:therapeutic use; D000069445:Atomoxetine Hydrochloride; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D015897:Comorbidity; D016316:Guanfacine / Q000627:therapeutic use*; D006801:Humans; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy / Q000503:physiopathology; D011437:Propylamines / Q000627:therapeutic use*; D005879:Tourette Syndrome / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D000316:Adrenergic alpha-Agonists; D014150:Antipsychotic Agents; D011437:Propylamines; D016316:Guanfacine; D000069445:Atomoxetine Hydrochloride