Membrane fusion: caught in a trap.
SNAREs are small coiled-coil proteins required for specific membrane fusion events in eukaryotic cells. Recent evidence points to the existence of an inhibitory class of SNAREs, i-SNAREs, which prevent incorrect fusions from occurring, adding a further layer of regulation to the process of membrane docking and fusion.
Short
Benjamin
B
Department of Cell Biology, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18, Martinsried, 82152 Germany. short@biochem.mpg.de
Barr
Francis A
FA
D006056:Golgi Apparatus / Q000378:metabolism; D008081:Liposomes / Q000378:metabolism; D008561:Membrane Fusion / Q000502:physiology*; D008565:Membrane Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism* / Q000502:physiology; D050600:SNARE Proteins; D033921:Vesicular Transport Proteins; D020691:rab GTP-Binding Proteins / Q000378:metabolism
D008081:Liposomes; D008565:Membrane Proteins; D050600:SNARE Proteins; D033921:Vesicular Transport Proteins; D020691:rab GTP-Binding Proteins