title: Unusual metastatic features in a patient with concomitant malignant orbital melanoma and prostate carcinoma.
abstract: A 73-year-old man with a history of malignant orbital melanoma and prostate carcinoma was admitted for progressive visual disturbance. Brain magnetic resonance imaging showed a suprasellar enhancing nodular lesion with major impingement on the anterior optical ways and sellar invasion. The extensive imaging work-up could not demonstrate with certainty its origin. Surprisingly, the transphenoidal biopsy of this patient revealed a prostate cancer metastasis outlining the importance of a histopathological diagnosis of cerebral metastases in patients with multiple malignancies when there is a doubt about the nature of the lesion.
authors.affiliation: Medical Oncology Unit, Centre du Cancer, Université Catholique de Louvain, Brussels, Belgium.
authors.forename: Catherine
authors.initials: C
authors.lastname: Ars
authors.forename: Lionel
authors.initials: L
authors.lastname: Duck
authors.forename: Jean-Francois
authors.initials: JF
authors.lastname: Baurain
authors.forename: Pierre
authors.initials: P
authors.lastname: Moulin
authors.forename: Thierry
authors.initials: T
authors.lastname: Duprez
authors.forename: Jean-Pascal
authors.initials: JP
authors.lastname: Machiels
mesh_terms: D000230:Adenocarcinoma / Q000737:chemistry / Q000556:secondary*; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001932:Brain Neoplasms / Q000737:chemistry / Q000556:secondary; D006801:Humans; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging; D008297:Male; D008545:Melanoma / Q000737:chemistry / Q000556:secondary*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009918:Orbital Neoplasms / Q000737:chemistry / Q000473:pathology*; D010911:Pituitary Neoplasms / Q000737:chemistry / Q000556:secondary*; D011471:Prostatic Neoplasms / Q000737:chemistry / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor