Donepezil for alcohol-related dementia: a case report.
A 75-year old man with a 40-year history of alcoholism was admitted to the hospital for intoxication and inability to care for himself. He had been admitted frequently in the past for detoxification and rehabilitation. The patient had no family history of Alzheimer's disease, no history of head injury, and single-photon emission computed tomography showed no typical findings of Alzheimer's disease. His cognitive function was impaired. He was treated with donepezil for alcohol-related dementia, and 3 months later, his cognitive function had improved. More research is needed to confirm donepezil's role in treating alcohol-related dementia.
Kim
Kye Y
KY
Extended Care Psychiatry Program, Salem Veterans Affairs Medical Center, Salem, Virginia 24153, USA. kye.kim@med.va.gov
Ke
Victoria
V
Adkins
Laurie M
LM
D000368:Aged; D019973:Alcohol-Related Disorders / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D003072:Cognition Disorders / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D000077265:Donepezil; D004334:Drug Administration Schedule; D006801:Humans; D007189:Indans / Q000627:therapeutic use*; D007267:Injections; D008297:Male; D010880:Piperidines / Q000627:therapeutic use*; D013997:Time Factors; D016896:Treatment Outcome; D014805:Vitamin B 12 / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use; D014806:Vitamin B 12 Deficiency / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy
D007189:Indans; D010880:Piperidines; D000077265:Donepezil; D014805:Vitamin B 12