Array-A-Lizer: a serial DNA microarray quality analyzer.
BACKGROUND
The proliferate nature of DNA microarray results have made it necessary to implement a uniform and quick quality control of experimental results to ensure the consistency of data across multiple experiments prior to actual data analysis.


RESULTS
Array-A-Lizer is a small and convenient stand-alone tool providing the necessary initial analysis of hybridization quality of an unlimited number of microarray experiments. The experiments are analyzed for even hybridization across the slide and between fluorescent dyes in two-color experiments in spotted DNA microarrays.


CONCLUSIONS
Array-A-Lizer allows the expedient determination of the quality of multiple DNA microarray experiments allowing for a rapid initial screening of results before progressing to further data analysis. Array-A-Lizer is directed towards speed and ease-of-use allowing both the expert and non-expert microarray researcher to rapidly assess the quality of multiple microarray hybridizations. Array-A-Lizer is available from the Internet as both source code and as a binary installation package.
Petri
Andreas
A
Department of Molecular Genetics, Novo Nordisk A/S, Bagsvaerd, 2880, Denmark. andp@novonordisk.com
Fleckner
Jan
J
Matthiessen
Mads Wichmann
MW
D003196:Computer Graphics / Q000706:statistics & numerical data; D020869:Gene Expression Profiling / Q000592:standards*; D020411:Oligonucleotide Array Sequence Analysis / Q000592:standards*; D011786:Quality Control; D012984:Software / Q000592:standards*; D014584:User-Computer Interface