title: A mechanism for the development of subepithelial deposits in a patient with type III membranoproliferative glomerulonephritis.
abstract: We report on a patient with membranoproliferative glomerulonephritis (MPGN) type III, whose repeated renal biopsies show evolution from a type I-like pattern to a type III pattern of immune complex formation over a 1-year period. Based on the development of experimental in situ immune complex glomerulonephritis, we discuss possible mechanisms for the formation of subepithelial deposits in type III MPGN with reference to an experimental in situ immune complex model of glomerulonephritis.
authors.affiliation: The First Department of Medicine, Hamamatsu University School of Medicine, Handayama, Hamamatsu, Japan. yf0516@hama-med.ac.jp
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Fujigaki
authors.forename: Naro
authors.initials: N
authors.lastname: Ohashi
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Yonemura
authors.forename: Taiki
authors.initials: T
authors.lastname: Fujimoto
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Fukasawa
authors.forename: Akashi
authors.initials: A
authors.lastname: Togawa
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Suzuki
authors.forename: Hideo
authors.initials: H
authors.lastname: Yasuda
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Akira
authors.initials: A
authors.lastname: Hishida
mesh_terms: D000328:Adult; D000936:Antigen-Antibody Complex; D002196:Capillaries / Q000473:pathology; D004848:Epithelium / Q000276:immunology / Q000473:pathology; D005260:Female; D015432:Glomerulonephritis, Membranoproliferative / Q000276:immunology* / Q000473:pathology*; D006801:Humans; D007668:Kidney / Q000098:blood supply / Q000276:immunology / Q000473:pathology
chemical_list: D000936:Antigen-Antibody Complex