Y-STR polymorphism in Central Anatolian Region of Turkey.
Eight Y-chromosome specific STR (Y-STR) loci including DYS19, DYS388, DYS389I, DYS389II, DYS390, DYS391, DYS392 and DYS393 were investigated in a group of males from Central Anatolian Region of Turkey. Healthy 59 males living in this region for at least three generations were included in the study. PCR analysis was carried out with Y-STR specific primers on genomic DNA obtained from peripheral blood samples and size determination of PCR products was performed by silver staining following 6% polyacrylamide gel electrophoresis (PAGE). DYS388 was found to be the locus with lowest diversity (D) whereas DYS389II was the locus with highest diversity. The current study presented a framework of variation for the eight Y-STR loci in Central Anatolian population.
Rustamov
Aydin
A
Department of Medical Biology, Ankara University School of Medicine, Ankara, Turkey. arustamov@yahoo.com
Gümüş
Güvem
G
Karabulut
Halil Gürhan
HG
Elhan
Atilla Halil
AH
Kadikiran
Ahmet
A
Bökesoy
Işik
I
D041322:Chromosomes, Human, Y; D016172:DNA Fingerprinting / Q000379:methods; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences; D014421:Turkey