title: [Clinical study on treatment of 405 cases of irregular menstruation by tiaojing zhixue granules].
abstract: OBJECTIVE
  To provide scientific and objective basis for Tiaojing zhixue granules treating irregular menstruation of clinical effect.
  
  
  METHODS
  Choose 405 cases suffering from irregular menstruation and make a systematic study 304 patients were treated with Tiaojing Zhixue granules, 101 patients received Fuxuening treatment.
  
  
  RESULTS
  After treatment, the obvious effective rate of Tiaojing Zhixue granules was 78.3% and the total effective rate 97.4%, granule cure rate of Fuxuening was 38.6% and the total effective rate 87.1%. Comparison showed significant difference (P < 0.001). Safety spithetical observation did not discover harmful effects and toxicity and side effects antagonize common symptoms 26 entries of clinical studying, the 7 entry are: weary and tired, short breaths, sore loins, weak knees, insomnia and eccessive dreaming, rapid and thready pulse, colliquative, distending pain in the lower abdomen and hypochondria. Among them, the comparison showed significant difference about treatments(P < 0.01-0.001).
  
  
  CONCLUSIONS
  Tiaojing Zhixue granules treatment irregular menstruation are scientific and effective.
authors.affiliation: Department of Education Management, China Academy of Traditional Chinese Medicine, Beijing 100700, China.
authors.forename: Kun
authors.initials: K
authors.lastname: Ma
authors.forename: Li-hua
authors.initials: LH
authors.lastname: Sun
authors.forename: Qing-hua
authors.initials: QH
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D027885:Astragalus propinquus / Q000737:chemistry; D029745:Codonopsis / Q000737:chemistry; D003937:Diagnosis, Differential; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008516:Medicine, Chinese Traditional; D008599:Menstruation Disturbances / Q000175:diagnosis / Q000188:drug therapy*; D008875:Middle Aged; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal