title: Spectroscopic investigation of interactions between dipeptides and vanadate(V) in solution.
abstract: The reaction of vanadate(V) with a series of dipeptides (Val-Gln, Ala-Gln, Gly-Gln, Gly-Glu, and Ala-Gly) was investigated by UV-visible spectroscopy and multinuclear ((51)V, (14)N, (13)C) NMR spectroscopy in solution. It was possible to evaluate the formation constants of the corresponding complexes for which a molecular structure was proposed. Complex formation is favored by the presence of a functionalized or a sterically demanding side chain. The Val-Gln dipeptide which combines both properties exhibits one of the highest formation constant reported so far for dipeptides.
authors.affiliation: Laboratoire Chimie de la Matière Condensée, UMR CNRS 7574, Tour 54 E5, Université Pierre et Marie Curie (Paris 6), 4 place Jussieu, 75252 Paris Cedex 05, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Durupthy
authors.forename: Aurélie
authors.initials: A
authors.lastname: Coupé
authors.forename: Lawrence
authors.initials: L
authors.lastname: Tache
authors.forename: Marie-Noëlle
authors.initials: MN
authors.lastname: Rager
authors.forename: Jocelyne
authors.initials: J
authors.lastname: Maquet
authors.forename: Thibaud
authors.initials: T
authors.lastname: Coradin
authors.forename: Nathalie
authors.initials: N
authors.lastname: Steunou
authors.forename: Jacques
authors.initials: J
authors.lastname: Livage
mesh_terms: D004151:Dipeptides / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012996:Solutions / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D014638:Vanadates / Q000737:chemistry*
chemical_list: D004151:Dipeptides; D012996:Solutions; D014638:Vanadates