title: Proliferative vitreoretinopathy--at what risk is the fellow eye?
abstract: OBJECTIVE
  To find out if patients with proliferative vitreoretinopathy (PVR) due to complicated retinal detachment are at risk to acquire the same disease or other vision-threatening retinal abnormalities in the fellow eye. To furthermore assess in what time-period they appear and if subgroups of patients have special risks.
  
  
  METHODS
  100 consecutive PVR-patients were studied retrospectively. 21 patients with PVR graded lower than C3, traumatic PVR, diabetic retinopathy or congenital vitreoretinal diseases were excluded. Age, gender, best-corrected visual acuity at the first and last visit, refraction, ocular disease in both eyes and observation-time were recorded.
  
  
  RESULTS
  After a mean follow-up of 8.5 years, 42 of 79 patients (53.4%) showed vision-threatening abnormalities in their fellow eyes: among them, 9 patients (11.4%) had PVR, 13 (16%) simple retinal detachments and 14 (17.3%) retinal breaks. Abnormalities in the fellow eye did not develop after a certain time following surgery of the primary eye; 71.4% appeared within 5 years. Aphakic and pseudophakic patients had retinal breaks significantly more often (p = 0.011) than phakic patients. Myopia did not increase the risk for any abnormality. Men developed retinal detachment (p = 0.037) and PVR (p = 0.025) significantly more often than women.
  
  
  CONCLUSIONS
  Patients with PVR have a greater than 50% risk of developing vision-threatening retinal abnormalities in their fellow eye. Because of this increased risk, these patients need regularly-scheduled long-term follow-up.
  
  
  CONCLUSIONS
  Patients with PVR have a greater than 50% risk of developing vision-threatening retinal abnormalities in their fellow eye and a 37% risk to develop PVR from rhegmatogenous retinal detachment. More than two thirds of abnormalities in the fellow eye developed within five years of surgery of the primary eye.
authors.affiliation: Department of Ophthalmology, University of Vienna, Vienna General Hospital, Vienna, Austria.
authors.forename: Sibylla
authors.initials: S
authors.lastname: Richter-Mueksch
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Kiss
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Radner
authors.forename: Susanne
authors.initials: S
authors.lastname: Binder
authors.forename: Michaela
authors.initials: M
authors.lastname: Velikay-Parel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008432:Mathematical Computing; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D012008:Recurrence; D012086:Reoperation / Q000706:statistics & numerical data; D012163:Retinal Detachment / Q000150:complications / Q000601:surgery; D012167:Retinal Perforations / Q000150:complications / Q000601:surgery; D012189:Retrospective Studies; D012306:Risk; D018630:Vitreoretinopathy, Proliferative / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery