Endocytic recycling.
After endocytosis, most membrane proteins and lipids return to the cell surface, but some membrane components are delivered to late endosomes or the Golgi. We now understand that the pathways taken by internalized molecules that eventually recycle to the cell surface can be surprisingly complex and can involve a series of sorting events that occur in several organelles. The molecular basis for many of these sorting processes is only partly understood.
Maxfield
Frederick R
FR
Department of Biochemistry, Weill Medical College of Cornell University, 1300 York Avenue, New York, New York 10021, USA. frmaxfie@med.cornell.edu
McGraw
Timothy E
TE
D000818:Animals; D001692:Biological Transport / Q000502:physiology; D002462:Cell Membrane / Q000378:metabolism*; D022163:Clathrin-Coated Vesicles / Q000378:metabolism; D004705:Endocytosis; D011992:Endosomes / Q000378:metabolism; D050356:Lipid Metabolism; D015388:Organelles / Q000378:metabolism; D021381:Protein Transport; D020691:rab GTP-Binding Proteins / Q000378:metabolism
D020691:rab GTP-Binding Proteins