Cortical bases of speech perception: evidence from functional lesion studies.
Functional lesion studies have yielded new information about the cortical organization of speech perception in the human brain. We will review a number of recent findings, focusing on studies of speech perception that use the techniques of electrocortical mapping by cortical stimulation and hemispheric anesthetization by intracarotid amobarbital. Implications for recent developments in neuroimaging studies of speech perception will be discussed. This discussion will provide the framework for a developing model of the cortical circuitry critical for speech perception.
Boatman
Dana
D
Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA. dboatma@jhmi.edu
D000654:Amobarbital / Q000008:administration & dosage / Q000494:pharmacology; D001303:Auditory Cortex / Q000187:drug effects / Q000503:physiopathology*; D001931:Brain Mapping / Q000295:instrumentation; D004827:Epilepsy / Q000503:physiopathology*; D007839:Functional Laterality / Q000502:physiology; D018757:GABA Modulators / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D013067:Speech Perception / Q000187:drug effects / Q000502:physiology*
D018757:GABA Modulators; D000654:Amobarbital