[Alterations in cholesterol, triglyceride and total phospholipid levels in plasma of Callithrix jacchus (sagüi) reinfected by Schistosoma mansoni].
Little information is available on the lipid changes caused by Schistosoma mansoni reinfection. In this work it was evaluated alteration in the plasma lipids due to one reinfection by Schistosoma mansoni in the non human primate Callithrix jacchus (sagüi). Blood samples from C. jacchus, prior and after 60 days infection and reinfection, were collected by intravenous puncture, anticoagulated with EDTA (1mg/mL) and centrifuged at 2,500 xg, in order to obtain the plasma. Total cholesterol, cholesteryl ester, total phospholipid and triglyceride levels were determined by spectrophotometer methods. The results showed that there are significant reduction in cholesterol total, cholesteryl ester, total phospholipid and triglyceride concentrations in plasma of animals reinfected by Schistosoma mansoni, in comparison to the same animals prior and after one infection. This study showed that a second infection of Callithrix jacchus by Schistosoma mansoni causes plasma lipid alterations, which are more significant than after a single infection.
Ramos
Thadzia Maria de Brito
TM
Laboratório de Química e Metabolismo de Lipídeos e Lipoproteínas, Centro de Ciências Biológicas, Universidade Federal de Pernambuco, Recife, PE, Brasil. vlml@ufpe.br
de Vasconcelos
Amanda Soares
AS
de Carvalho
Vera Cristina Oliveira
VC
Lima
Vera Lúcia de Menezes
VL
D000818:Animals; D002144:Callithrix / Q000097:blood* / Q000469:parasitology; D002784:Cholesterol / Q000097:blood*; D008297:Male; D010743:Phospholipids / Q000097:blood*; D012008:Recurrence; D012555:Schistosomiasis mansoni / Q000097:blood*; D013053:Spectrophotometry; D014280:Triglycerides / Q000097:blood*
D010743:Phospholipids; D014280:Triglycerides; D002784:Cholesterol