title: Positron emission tomography in central nervous system drug discovery and development.
abstract: Genetics, neuroscience, and imaging science have advanced greatly in the last few years. These advances can be brought together and applied in creative new ways to make available better drugs for treating neuropsychiatric disorders and for getting candidate drugs through the development process faster. One particular approach, built around [18F]fluordeoxyglucose positron emission tomography, is described.
authors.affiliation: Department of Radiology, University of Chicago, 2843 West Rascher, Chicago, IL 60625, USA.
authors.forename: Malcolm
authors.initials: M
authors.lastname: Cooper
authors.forename: John
authors.initials: J
authors.lastname: Metz
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000000981:diagnostic imaging* / Q000187:drug effects*; D002491:Central Nervous System Agents / Q000494:pharmacology*; D015195:Drug Design; D006801:Humans; D014055:Tomography, Emission-Computed
chemical_list: D002491:Central Nervous System Agents