Using Caenorhabditis elegans to probe toxicity of 1-alkyl-3-methylimidazolium chloride based ionic liquids.
Ionic liquids are gaining attention as new solvents within the green chemistry community; however this attention has quickly outstripped current environmental and toxicological data available. In the present communication, we establish the use of Caenorhabditis elegans as a model organism for inexpensively and quickly exploring toxicological effects of 1-alkyl-3-methylimidazolium chloride ionic liquids.
Swatloski
Richard P
RP
Department of Chemistry and Center for Green Manufacturing, The University of Alabama, Tuscaloosa, 35487, USA.
Holbrey
John D
JD
Memon
Shermeen B
SB
Caldwell
Guy A
GA
Caldwell
Kim A
KA
Rogers
Robin D
RD
D000818:Animals; D001681:Biological Assay / Q000379:methods*; D017173:Caenorhabditis elegans / Q000187:drug effects* / Q000502:physiology; D007093:Imidazoles / Q000633:toxicity*; D007477:Ions / Q000633:toxicity*; D009348:Nematoda / Q000187:drug effects / Q000502:physiology; D012997:Solvents / Q000633:toxicity*; D018675:Toxicity Tests / Q000379:methods*
D007093:Imidazoles; D007477:Ions; D012997:Solvents