[Phanerogenetic retrocochlear low frequency hearing loss].
OBJECTIVE
To study the pathogenisis of retrocochlear low frequency hearing loss.


METHODS
Clinical and audiologic findings [auditory brainstem response (ABR), evoked otoacoustic emission (EOAE), et al] of 29 cases with retrocochlear low frequency hearing loss were studied.


RESULTS
The head injury, acoustic neuroma, peripheral neurophathy, hereditary hear loss, multiple sclerosis and brainstem disease can cause retrocochlear low frequency hearing loss. The typical clinical manifestations of retrocochlear low frequency hearing loss were normal EOAE which cannot be suppressed by contralateral white noise, but with abnormal ABR as well as with no acoustic reflex and -SP/AP > 0.44.


CONCLUSIONS
The results suggest that phanerogenetic retrocochlear low frequency hearing loss should be a syndrome rather than a disease called "auditory neuropathy". The main lesions of the disease are brainstem, cochlear nuclei and auditory nerve.
Han
Wei-ju
WJ
Department of Otorhinolaryngology and Head & Neck Surgery, General Hospital of PLA, Beijing 100853, China.
Gu
Rui
R
Yu
Li-ming
LM
Zheng
Jie-fu
JF
Zhou
Na
N
Cao
Ju-yang
JY
Wang
Li
L
D000293:Adolescent; D000328:Adult; D020295:Brain Stem Neoplasms / Q000150:complications / Q000175:diagnosis; D002648:Child; D003390:Cranial Nerve Neoplasms / Q000150:complications* / Q000175:diagnosis; D006259:Craniocerebral Trauma / Q000150:complications / Q000175:diagnosis; D003937:Diagnosis, Differential; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000145:classification* / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000150:complications* / Q000175:diagnosis; D017084:Otoacoustic Emissions, Spontaneous; D010523:Peripheral Nervous System Diseases / Q000150:complications / Q000175:diagnosis; D014725:Vestibular Nerve