title: [Studies on the constituents from the herb of Vernonia patula].
abstract: OBJECTIVE
  To isolate and elucidate the chemical constituents of the whole plant of Vernonia patula, and to provide samples for biological activity screening.
  
  
  METHODS
  The chromatography on silica gel was used and the structures were determined by IR, NMR and MS spectra analysis and physicochemical property comparion.
  
  
  RESULTS
  Four triterpenoids were isolated and identified as bauerenyl acetate(I), friedelin(II), epifriedelanol(III), 20(30)-taraxastene-3 beta, 21 alpha-diol(IV).
  
  
  CONCLUSIONS
  Compounds I and IV were isolated from genus Vernonia for the first time and compounds II and III were isolated from the whole plant of V. patula for the first time. The four compounds show no inhibitory effect on the growing of PC-12 cells.
authors.affiliation: Nanjing Normal University, Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu, China. liangqiaoli@sohu.com
authors.forename: Qiao-li
authors.initials: QL
authors.lastname: Liang
authors.forename: Zhi-da
authors.initials: ZD
authors.lastname: Min
mesh_terms: D000818:Animals; D002455:Cell Division / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D016716:PC12 Cells; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D035741:Vernonia / Q000737:chemistry*; D000094042:Lupanes
chemical_list: D004365:Drugs, Chinese Herbal; D009828:Oleanolic Acid; D014315:Triterpenes; C477171:bauerenyl acetate; C055670:friedelinol; C060796:friedelin; D000094042:Lupanes