title: Cochlioquinones and epi-cochlioquinones: antagonists of the human chemokine receptor CCR5 from Bipolaris brizae and Stachybotrys chartarum.
authors.affiliation: MerLion Pharmaceuticals, 59A Science Park Drive, The Fleming, Singapore Science Park, Singapore, 118240. yoga@merlionpharma.com
authors.forename: K
authors.initials: K
authors.lastname: Yoganathan
authors.forename: Lay-kien
authors.initials: LK
authors.lastname: Yang
authors.forename: Christine
authors.initials: C
authors.lastname: Rossant
authors.forename: Yicun
authors.initials: Y
authors.lastname: Huang
authors.forename: Siewbee
authors.initials: S
authors.lastname: Ng
authors.forename: Mark S
authors.initials: MS
authors.lastname: Butler
authors.forename: Antony D
authors.initials: AD
authors.lastname: Buss
mesh_terms: D000818:Animals; D001203:Ascomycota / Q000737:chemistry* / Q000378:metabolism; D016227:Benzoquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism / Q000494:pharmacology*; D001667:Binding, Competitive; D065100:CCR5 Receptor Antagonists; D016466:CHO Cells; D054407:Chemokine CCL4; D006224:Cricetinae; D005285:Fermentation; D006801:Humans; D020128:Inhibitory Concentration 50; D019402:Macrophage Inflammatory Proteins / Q000378:metabolism; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D019713:Receptors, CCR5 / Q000378:metabolism; D021241:Spectrometry, Mass, Electrospray Ionization; D013191:Stachybotrys / Q000737:chemistry* / Q000378:metabolism
chemical_list: D016227:Benzoquinones; D065100:CCR5 Receptor Antagonists; D054407:Chemokine CCL4; D019402:Macrophage Inflammatory Proteins; D019713:Receptors, CCR5; C066134:cochlioquinone A