[Study on process of removing impurity from water-extraction of gutianquan-capsule].
OBJECTIVE
To study the result of removing impurity from water-extraction of Gutianquan-capsule with macro-reticular absorbing resin, chitosans clarification, water-extraction and alcohol-precipitation methods.


METHODS
Coefficient of Unguent of macro-reticular absorbing resin, chitosans clarification method, water-extraction and alcohol-precipitation methods were compared, and qualitative assay of Ginsenoside Rg1, Re, and snide measurement of Ginsenoside Rg1, Ferulic acid, and stability experiment were made.


RESULTS
Coefficient of Unguent of water-extraction and alcohol-precipitation method was 17.2%, Coefficient of Unguent of chitosans clarification method was 12.8%, and macro-reticular absorbing resin method was 3.1%. They could clarify liquor of water-extraction.


CONCLUSIONS
Chitosans clarification method is suitable for process of Gutianquan-capsule.
Guo
Sheng-wei
SW
Nanjing University of TCM, Nanjing 210029, Jiangsu, China.
Cai
Bao-chang
BC
Li
Dan
D
Wang
Tian-shan
TS
D000818:Animals; D002214:Capsules; D002686:Chitin / Q000031:analogs & derivatives*; D048271:Chitosan; D003373:Coumaric Acids / Q000032:analysis*; D004338:Drug Combinations; D004340:Drug Contamination; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000737:chemistry* / Q000302:isolation & purification; D036145:Ginsenosides / Q000032:analysis*; D020050:Mantodea / Q000737:chemistry; D008419:Materia Medica / Q000008:administration & dosage / Q000737:chemistry* / Q000302:isolation & purification; D005894:Panax / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*
D002214:Capsules; D003373:Coumaric Acids; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D036145:Ginsenosides; D008419:Materia Medica; D002686:Chitin; D048271:Chitosan; C004999:ferulic acid; C035054:ginsenoside Rg1