title: Magnetic resonance microscopy of biofilm structure and impact on transport in a capillary bioreactor.
abstract: Microorganisms that colonize surfaces, biofilms, are of significant importance due to their role in medical infections, subsurface contaminant remediation, and industrial processing. Spatially resolved data on the distribution of biomass within a capillary bioreactor, the heterogeneity of the biofilm itself and the impact on transport dynamics for a Staphylococcus epidermidis biofilm in the natural growth state are presented. The data demonstrate the ability of magnetic resonance microscopy to study spatially resolved processes in bacterial biofilms, thus providing a basis for future studies of spatially resolved metabolism and in vivo clinical detection.
authors.affiliation: Department of Chemical and Biological Engineering and Center for Biofilm Engineering, Montana State University, Bozeman, MT, USA. jseymour@coe.montana.edu
authors.forename: Joseph D
authors.initials: JD
authors.lastname: Seymour
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Codd
authors.forename: Erica L
authors.initials: EL
authors.lastname: Gjersing
authors.forename: Philip S
authors.initials: PS
authors.lastname: Stewart
mesh_terms: D018441:Biofilms / Q000254:growth & development*; D001693:Biological Transport, Active / Q000502:physiology; D019149:Bioreactors / Q000382:microbiology*; D002197:Capillary Action; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008853:Microscopy / Q000379:methods; D012212:Rheology / Q000379:methods*; D013212:Staphylococcus epidermidis / Q000166:cytology* / Q000502:physiology*; D014867:Water / Q000378:metabolism*
chemical_list: D014867:Water