title: A phase I vaccine safety and chemotherapy dose-finding trial of an allogeneic GM-CSF-secreting breast cancer vaccine given in a specifically timed sequence with immunomodulatory doses of cyclophosphamide and doxorubicin.
authors.affiliation: Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21231-2410, USA. emensle@jhmi.edu
authors.forename: Leisha A
authors.initials: LA
authors.lastname: Emens
authors.forename: Deborah
authors.initials: D
authors.lastname: Armstrong
authors.forename: Barbara
authors.initials: B
authors.lastname: Biedrzycki
authors.forename: Nancy
authors.initials: N
authors.lastname: Davidson
authors.forename: Janice
authors.initials: J
authors.lastname: Davis-Sproul
authors.forename: John
authors.initials: J
authors.lastname: Fetting
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Jaffee
authors.forename: Beth
authors.initials: B
authors.lastname: Onners
authors.forename: Steve
authors.initials: S
authors.lastname: Piantadosi
authors.forename: Richard T
authors.initials: RT
authors.lastname: Reilly
authors.forename: Vered
authors.initials: V
authors.lastname: Stearns
authors.forename: Irena
authors.initials: I
authors.lastname: Tartakovsky
authors.forename: Kala
authors.initials: K
authors.lastname: Visvanathan
authors.forename: Antonio
authors.initials: A
authors.lastname: Wolff
mesh_terms: D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000276:immunology / Q000628:therapy*; D019496:Cancer Vaccines / Q000009:adverse effects* / Q000235:genetics / Q000276:immunology; D045744:Cell Line, Tumor; D002985:Clinical Protocols; D017321:Clinical Trials, Phase I as Topic / Q000379:methods*; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage* / Q000627:therapeutic use; D004317:Doxorubicin / Q000008:administration & dosage* / Q000627:therapeutic use; D004334:Drug Administration Schedule; D005260:Female; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000235:genetics* / Q000276:immunology / Q000378:metabolism; D006801:Humans; D051379:Mice
chemical_list: D019496:Cancer Vaccines; D004317:Doxorubicin; D016178:Granulocyte-Macrophage Colony-Stimulating Factor; D003520:Cyclophosphamide