title: Hypolipidemic activity of seeds of Cassia tora Linn.
abstract: Ethanolic extract of seeds of Cassia tora L. and its fractions were investigated for hypolipidemic activity on triton induced hyperlipidemic profile. Ethanolic extract and its ether soluble and water soluble fraction decreased serum level of total cholesterol by 42.07, 40.77 and 71.25%, respectively. On the other hand ethanolic extract, ether soluble fraction and water soluble fraction increased the serum HDL-cholesterol level by 6.72, 17.20 and 19.18%, respectively. Ethanolic extract, ether fraction and water fraction decreased triglyceride level by 26.84, 35.74 and 38.46%, respectively. The reduction in LDL-cholesterol level by ethanolic extract, ether soluble fraction and water soluble fraction were 69.25, 72.06 and 76.12%, respectively.
authors.affiliation: Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar 470003, MP, India.
authors.forename: Umesh K
authors.initials: UK
authors.lastname: Patil
authors.forename: S
authors.initials: S
authors.lastname: Saraf
authors.forename: V K
authors.initials: VK
authors.lastname: Dixit
mesh_terms: D000818:Animals; D002366:Cassia / Q000737:chemistry; D005260:Female; D006949:Hyperlipidemias / Q000097:blood / Q000139:chemically induced / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000302:isolation & purification / Q000627:therapeutic use*; D008297:Male; D008517:Phytotherapy / Q000379:methods; D010936:Plant Extracts / Q000302:isolation & purification / Q000627:therapeutic use; D011092:Polyethylene Glycols / Q000633:toxicity; D051381:Rats; D017208:Rats, Wistar; D012639:Seeds / Q000737:chemistry
chemical_list: D000960:Hypolipidemic Agents; D010936:Plant Extracts; D011092:Polyethylene Glycols; C016811:tyloxapol