SARS-related virus predating SARS outbreak, Hong Kong.
Using immunofluorescence and neutralization assays, we detected antibodies to human severe acute respiratory syndrome-associated coronavirus (SARS-CoV) and/or animal SARS-CoV-like virus in 17 (1.8%) of 938 adults recruited in 2001. This finding suggests that a small proportion of healthy persons in Hong Kong had been exposed to SARS-related viruses at least 2 years before the recent SARS outbreak.
Zheng
Bo Jian
BJ
University of Hong Kong, Hong Kong Special Administration Region, People's Republic of China.
Wong
Ka Hing
KH
Zhou
Jie
J
Wong
Kin Ling
KL
Young
Betty Wan Y
BW
Lu
Li Wei
LW
Lee
Shui Shan
SS
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D004196:Disease Outbreaks; D005260:Female; D005455:Fluorescent Antibody Technique; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009500:Neutralization Tests; D045473:Severe acute respiratory syndrome-related coronavirus / Q000276:immunology*; D045169:Severe Acute Respiratory Syndrome / Q000453:epidemiology* / Q000276:immunology / Q000821:virology*
D000914:Antibodies, Viral