Redox cycling of beta-lapachone and structural analogues in microsomal and cytosol liver preparations.
Fernández Villamil
Silvia
S
Bioenergetics Research Centre, National Research Council, School of Medicine, University of Buenos Aires, Argentine.
Stoppani
Andrés O M
AO
Dubin
Marta
M
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use; D003600:Cytosol / Q000201:enzymology / Q000378:metabolism*; D004578:Electron Spin Resonance Spectroscopy; D006801:Humans; D008110:Liver Extracts / Q000378:metabolism*; D008861:Microsomes / Q000201:enzymology / Q000378:metabolism*; D015394:Molecular Structure; D009249:NADP / Q000378:metabolism; D009251:NADPH-Ferrihemoprotein Reductase / Q000378:metabolism; D009285:Naphthoquinones / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D009369:Neoplasms / Q000188:drug therapy / Q000378:metabolism; D010084:Oxidation-Reduction; D017382:Reactive Oxygen Species / Q000378:metabolism* / Q000633:toxicity
D000970:Antineoplastic Agents; D008110:Liver Extracts; D009285:Naphthoquinones; D017382:Reactive Oxygen Species; D009249:NADP; C014638:beta-lapachone; C040756:1,2-naphthoquinone; D009251:NADPH-Ferrihemoprotein Reductase