The role of intrauterine bacteria in brain injury.
Organisms appear to be present in human fetal membranes without any apparent impact on pregnancy maintenance or the fetal brain. A clear link between chorioamnionitis and fetal brain damage suggests that tissue responses at the feto-maternal interface may be the key determinant of whether preterm labour and brain damage occur.
Sullivan
M H F
MH
Department of Obstetrics & Gynaecology, Imperial College of Science, Technology & Medicine, Institute of Reproductive & Developmental Biology, Hammersmith Hospital, DuCane Road, London, UK.
Steel
J
J
Kennea
N
N
Feldman
R G
RG
Edwards
A D
AD
D001424:Bacterial Infections / Q000150:complications*; D001930:Brain Injuries / Q000209:etiology* / Q000378:metabolism; D015331:Cohort Studies; D005321:Extraembryonic Membranes / Q000382:microbiology; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D017493:Leukocyte Common Antigens / Q000378:metabolism; D007752:Obstetric Labor, Premature / Q000209:etiology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology; D014599:Uterus / Q000382:microbiology*
D017493:Leukocyte Common Antigens