[Studies on saponin constituents in roots of Panax quinquefolium].
OBJECTIVE
To examine the saponins constituents in roots of Panax quinquefolium cultivated in China.


METHODS
The methanol extract from roots of P. quinquefolium cultivated in Jiling province of China was extracted by chloroform and n-butanol successively. Ten pure saponins were isolated from the n-butanol extract by silica gel and RP-8 reversed-phase column chromatography. Their structures were identified by means of spectral methods and compared with known compounds.


RESULTS
Ten saponins were isolated from P. quinquefolium. They were identified as ginsenoside Rg1(2), Re(5), Rd(7), Rc(8), Rb1(9), Rb2(10), 24(R)-ginsenoside Rg3(3), 24(R)-pseudoginsenoside RT5(1), F11(4) and notoginsenoside K(6), respectively.


CONCLUSIONS
This work has elucidated the saponins constituents of P. quinquefolium cultivated in Jilin province of China and has shown that compound 1 was isolated from this plant for the first time.
Su
Jian
J
Yunnan Institute for Drug Control, Kunming 650011, Yunnan, China. sujian-km@163.com
Li
Hai-Zhou
HZ
Yang
Chong-Ren
CR
D002681:China; D036145:Ginsenosides / Q000737:chemistry / Q000302:isolation & purification; D005894:Panax / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*
D036145:Ginsenosides; D012503:Saponins; C442759:ginsenoside Rb1; C487714:pseudoginsenoside RT5; C035054:ginsenoside Rg1