title: Stromal invasion of the prostate following a complete response to bacillus Calmette-Guerin instillation therapy for carcinoma in situ of the ureter and the bladder.
abstract: Bacillus Calmette-Guerin (BCG) instillation therapy is now a standard therapy for high-risk superficial bladder cancer patients. Although the complete response rate is approximately 70%, extra-vesical progression is sometimes observed. In particular, those patients who present a positive urinary cytology even after complete response from bladder lesion should be thoroughly examined. We present two cases of stromal invasion of the prostate after complete remission by BCG therapy of carcinoma in situ of the ureter and bladder found by transrectal prostate biopsy.
authors.affiliation: Division of Urology, Kobe University Graduate School of Medicine, Kobe, Japan. hara@med.kobe-u.ac.jp
authors.forename: Isao
authors.initials: I
authors.lastname: Hara
authors.forename: Akihisa
authors.initials: A
authors.lastname: Yao
authors.forename: Mototsugu
authors.initials: M
authors.lastname: Muramaki
authors.forename: Satoko
authors.initials: S
authors.lastname: Hikosaka
authors.forename: Yuji
authors.initials: Y
authors.lastname: Yamada
authors.forename: Gaku
authors.initials: G
authors.lastname: Kawabata
authors.forename: Sadao
authors.initials: S
authors.lastname: Kamidono
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000368:Aged; D001500:BCG Vaccine / Q000627:therapeutic use; D002278:Carcinoma in Situ / Q000473:pathology* / Q000628:therapy; D015653:Cystectomy; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000556:secondary* / Q000601:surgery; D017154:Stromal Cells / Q000473:pathology*; D014516:Ureteral Neoplasms / Q000473:pathology* / Q000628:therapy; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000628:therapy
chemical_list: D000276:Adjuvants, Immunologic; D001500:BCG Vaccine