title: Single-site modifications and their effect on the folding stability of m-phenylene ethynylene oligomers.
abstract: [reaction: see text] The folded structure of a m-phenylene ethynylene oligomer is tolerant to single-site modifications to both the backbone sequence and end groups. The helical structure is reinforced by multiple noncovalent interactions, allowing the oligomer sequence to be customized without a significant change in stability in most cases. The small changes that are observed are consistent with the expected behavior of pi-stacked systems and demonstrate subtle control over folding through single-site modifications.
authors.affiliation: Department of Chemistry and Materials Science & Engineering, 600 South Mathews Avenue, The University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Goto
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: Heemstra
authors.forename: David J
authors.initials: DJ
authors.lastname: Hill
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Moore