Aged skin: detection of alterations of major collagen types ratio by image processing of electron-optical data.
Automated algorithms are developed in this paper based on digital signal processing to correlate electron-optical data from skin collagen fibrils with known sequence data. In particular, they detect alterations on the ratio of major collagen types in skin upon age.
Tzaphlidou
Margaret
M
Laboratory of Medical Physics, Medical School, University of Ioannina, P.O. Box 1186, Ioannina 45110, Greece. mtzaphli@cc.uoi.gr
Zervakis
Michalis
M
D000465:Algorithms; D000818:Animals; D001331:Automation; D003094:Collagen / Q000032:analysis*; D005260:Female; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008854:Microscopy, Electron; D008962:Models, Theoretical; D020033:Protein Isoforms / Q000032:analysis*; D051381:Rats; D012867:Skin / Q000737:chemistry / Q000648:ultrastructure; D015595:Skin Aging / Q000473:pathology*
D020033:Protein Isoforms; D003094:Collagen