title: [Cardiovascular disease in HIV-infected patients on highly active antiretroviral therapy].
abstract: OBJECTIVE
  Our goal was to assess the main characteristics of cardiovascular disease in HIV-infected patients on highly active antiretroviral therapy (HAART).
  
  
  METHODS
  Retrospective analysis of the clinico-epidemiological characteristics of 16 HIV-infected patients treated with HAART who had suffered a cardiovascular event from a 1,459 patients' cohort.
  
  
  RESULTS
  Clinical presentation of cardiovascular disease was an acute coronary syndrome in 12 cases, ischemic stroke in 2 and peripheral vascular disease in 2. Patients included in the study had a mean of 3.2 cardiovascular risk factors, smoking and low HDL levels being the more prevalent risk factors. Eight (50%, 95% CI, 25-75%) patients fulfilled the criteria of metabolic syndrome. The mean CD4 count was 548 x 10(6)/l.
  
  
  CONCLUSIONS
  HIV-infected patients on HAART ha-ve a high cardiovascular risk. A strict management of modifiable risk factors must be warranted in these patients.
authors.affiliation: Servicio de Medicina Interna-Enfermedades Infecciosas, Hospital del Mar, Universidad Autónoma de Barcelona, Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: Jericó
authors.forename: Hernando
authors.initials: H
authors.lastname: Knobel
authors.forename: Alexia
authors.initials: A
authors.lastname: Carmona
authors.forename: M Luisa
authors.initials: ML
authors.lastname: Sorli
authors.forename: José Luis
authors.initials: JL
authors.lastname: López-Colomés
authors.forename: Juan
authors.initials: J
authors.lastname: Pedro-Botet
mesh_terms: D000328:Adult; D000368:Aged; D023241:Antiretroviral Therapy, Highly Active; D002318:Cardiovascular Diseases / Q000150:complications* / Q000517:prevention & control; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D015497:HIV-1; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors