Postmenopausal hormone therapy: the pros and cons.
The use of postmenopausal hormone therapy (HT) has recently generated much debate following the results of various large randomised controlled trials. This has challenged physicians to reassess the use of HT in each individual woman within the realm of her symptomatology and risk profile for long-term illnesses. There are several areas of definite benefit or risk and many areas of uncertainty. The results of recent randomised controlled trials pertain to the specific HT regimens used and the characteristics of the study groups, such that the conclusions cannot be extrapolated to the use of HT in general.
Rivera-Woll
L M
LM
The Jean Hailes Foundation, National Health and Medical Research Council Centre of Clinical Research Excellence, Department of Obstetrics and Gynaecology, Monash University, Melbourne, Victoria, Australia.
Davis
S R
SR
D001943:Breast Neoplasms / Q000209:etiology; D002318:Cardiovascular Diseases / Q000517:prevention & control; D003704:Dementia / Q000517:prevention & control; D015914:Estrogen Replacement Therapy / Q000009:adverse effects; D005260:Female; D006620:Hip Fractures / Q000517:prevention & control; D006801:Humans; D010051:Ovarian Neoplasms / Q000517:prevention & control; D011788:Quality of Life; D020521:Stroke / Q000517:prevention & control; D013923:Thromboembolism / Q000517:prevention & control; D020246:Venous Thrombosis / Q000517:prevention & control