[Sleep disorders with antipsychotic drugs: based on one case with clozapine].
Clozapine is a widely used atypical neuroleptic in the treatment of schizophrenia; its effects on sleep have been poorly studied, sedation being one of its side effects. We present the case of hypersomnia and marked reduction of REM sleep secondary to treatment with clozapine and review existing scientific literature on the action of neuroleptics on sleep.
Pérez Bravo
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Unidad de Salud Mental, Hospital Xeral de Vigo. avelina.perez@ya.com
Puñal
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MA
D000328:Adult; D003024:Clozapine / Q000009:adverse effects*; D006970:Disorders of Excessive Somnolence / Q000139:chemically induced*; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000188:drug therapy*; D012702:Serotonin Antagonists / Q000009:adverse effects*; D012895:Sleep, REM / Q000187:drug effects*
D012702:Serotonin Antagonists; D003024:Clozapine