title: Polarographic determination of diazepam with its parallel catalytic wave in the presence of persulfate.
abstract: A new method for the determination of diazepam was proposed based on its polarographic catalytic wave in the presence of persulfate. In 0.20 M NaAc-HAc (pH 4.7)-1.0 x 10(-2) M K(2)S(2)O(8) supporting electrolyte, the reduction wave of diazepam with peak potential -0.89 V (versus SCE) was catalyzed, producing a parallel catalytic wave. The peak current of the catalytic wave was 15 times higher than that of the corresponding reduction wave for 4.0 x 10(-6) M diazepam, and was rectilinear to diazepam concentration in the range of 5.6 x 10(-8) to 8.9 x 10(-6) and 8.8 x 10(-6) to 2.0 x 10(-4) M. The detection limit was 9.6 x 10(-9) M. The mechanism of the parallel catalytic wave of diazepam was discussed.
authors.affiliation: Department of Chemistry, Northwest University, Xi'an 710069, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Guo
authors.forename: Hong
authors.initials: H
authors.lastname: Lin
authors.forename: Limin
authors.initials: L
authors.lastname: Liu
authors.forename: Junfeng
authors.initials: J
authors.lastname: Song
mesh_terms: D002021:Buffers; D002384:Catalysis; D003975:Diazepam / Q000032:analysis* / Q000737:chemistry; D004563:Electrochemistry; D006863:Hydrogen-Ion Concentration; D016877:Oxidants / Q000737:chemistry; D011048:Polarography / Q000379:methods*; D017680:Potassium Compounds / Q000032:analysis* / Q000737:chemistry; D013431:Sulfates / Q000032:analysis* / Q000737:chemistry
chemical_list: D002021:Buffers; D016877:Oxidants; D017680:Potassium Compounds; D013431:Sulfates; C009007:potassium persulfate; D003975:Diazepam