Effect of alkyl-beta,d-glucopyranosides on hypertonic haemolysis of erythrocytes.
The effect of temperature (5-20 degrees C) and treatment with phenylhydrazine on the hypertonic lysis of erythrocytes in the presence of alkyl-beta,d-glucopyranosides was studied. The results highlight an important role for the cytoskeleton-membrane complex, which allows the cells to both withstand hypertonic stress within the temperature range studied and facilitate the protective effect of alkylglucopyranosides at low temperatures (5 degrees C).
Synchykova
Olga P
OP
Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of the Ukraine, Kharkov, Ukraine. cryo@online.kharkov
Shpakova
Natalia M
NM
Bondarenko
Valerij A
VA
D003599:Cytoskeleton / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004912:Erythrocytes / Q000187:drug effects* / Q000502:physiology; D005947:Glucose / Q000494:pharmacology*; D006461:Hemolysis / Q000187:drug effects*; D006801:Humans; D006982:Hypertonic Solutions / Q000494:pharmacology; D009996:Osmotic Fragility / Q000187:drug effects; D010659:Phenylhydrazines / Q000494:pharmacology; D012965:Sodium Chloride; D013696:Temperature
D006982:Hypertonic Solutions; D010659:Phenylhydrazines; C030299:phenylhydrazine; D012965:Sodium Chloride; D005947:Glucose