title: Positron emission tomography/computed tomography of a rare xanthogranulomatous process: Erdheim-Chester disease.
abstract: Erdheim-Chester disease (ECD) is a disseminated xanthogranulomatous infiltrative disease of unknown etiology due to infiltration of different organs and bones by foamy histiocytes. A 37-year-old male with cerebral and periorbital lesions was diagnosed with this rare disease and was evaluated with magnetic resonance imaging (MRI) and 2-deoxy-2-[(18)F]fluoro-D-glucose (FDG) with positron emission tomography/computed tomography (PET/CT) imaging at baseline and following therapy. FDG-PET imaging allowed accurate evaluation of the extent of the disease at baseline, as well as assessment of response to therapy.
authors.affiliation: Department of Radiology, Vanderbilt University Medical Center, Nashville, TN, USA.
authors.forename: Carlos Cunha
authors.initials: CC
authors.lastname: Pereira Neto
authors.forename: Chris
authors.initials: C
authors.lastname: Roman
authors.forename: Mahlon
authors.initials: M
authors.lastname: Johnson
authors.forename: Madan
authors.initials: M
authors.lastname: Jagasia
authors.forename: William H
authors.initials: WH
authors.lastname: Martin
authors.forename: Dominique
authors.initials: D
authors.lastname: Delbeke
mesh_terms: D000328:Adult; D031249:Erdheim-Chester Disease / Q000175:diagnosis / Q000000981:diagnostic imaging*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011379:Prognosis; D014055:Tomography, Emission-Computed; D014973:Xanthomatosis / Q000000981:diagnostic imaging
chemical_list: D019788:Fluorodeoxyglucose F18