title: [Clinical study of effect of tianzhi granule on senile vascular demetia].
abstract: OBJECTIVE
  To investigate the clinical effect of Tianzhi Granule (TZK) on senile vascular dementia (VaD), which is classified as sthenia of liver-yang.
  
  
  METHODS
  Two hundred VaD patients were treated with TZK (0.5 g/bag), which was taken one bag each, three times a day. The treatment course was one month and they were treated for rwo courses.
  
  
  RESULTS
  TZK could remarkably increase gnosia and activity, with no striking difference from that of positive control group (P > 0.05). Simultaneously, TZK could significantly improve the clinical syndrome of traditional Chinese medicine and viability. It could also drastically reduce the whole blood and plasma viscosity and improve erythrodegeneration and abnormality of aggregation index in the abnormal blood viscosity patients.
  
  
  CONCLUSIONS
  TMC has certain effects on senile VaD.
authors.affiliation: Inst. of CMM, China Academy of CTM, Beijing 100700, China.
authors.forename: Gui-you
authors.initials: GY
authors.lastname: Du
authors.forename: Xin-cheng
authors.initials: XC
authors.lastname: Zhu
authors.forename: Jian-jun
authors.initials: JJ
authors.lastname: Zhao
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.forename: Jin-zhou
authors.initials: JZ
authors.lastname: Tian
authors.forename: Xian-feng
authors.initials: XF
authors.lastname: Liu
authors.forename: Hui-ping
authors.initials: HP
authors.lastname: Zhi
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhao
authors.forename: Chun-yu
authors.initials: CY
authors.lastname: Cao
authors.forename: Hai-feng
authors.initials: HF
authors.lastname: Cui
authors.forename: Xiu-rong
authors.initials: XR
authors.lastname: Wang
authors.forename: Chun-ying
authors.initials: CY
authors.lastname: Zhang
mesh_terms: D000368:Aged; D001809:Blood Viscosity / Q000187:drug effects; D015140:Dementia, Vascular / Q000097:blood / Q000188:drug therapy*; D004311:Double-Blind Method; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000627:therapeutic use*; D004903:Erythrocyte Aggregation / Q000187:drug effects; D004907:Erythrocyte Deformability / Q000187:drug effects; D006801:Humans; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D021641:Recognition, Psychology / Q000187:drug effects
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal