[Clinical study of effect of tianzhi granule on senile vascular demetia].
OBJECTIVE
To investigate the clinical effect of Tianzhi Granule (TZK) on senile vascular dementia (VaD), which is classified as sthenia of liver-yang.


METHODS
Two hundred VaD patients were treated with TZK (0.5 g/bag), which was taken one bag each, three times a day. The treatment course was one month and they were treated for rwo courses.


RESULTS
TZK could remarkably increase gnosia and activity, with no striking difference from that of positive control group (P > 0.05). Simultaneously, TZK could significantly improve the clinical syndrome of traditional Chinese medicine and viability. It could also drastically reduce the whole blood and plasma viscosity and improve erythrodegeneration and abnormality of aggregation index in the abnormal blood viscosity patients.


CONCLUSIONS
TMC has certain effects on senile VaD.
Du
Gui-you
GY
Inst. of CMM, China Academy of CTM, Beijing 100700, China.
Zhu
Xin-cheng
XC
Zhao
Jian-jun
JJ
Wang
Jian
J
Tian
Jin-zhou
JZ
Liu
Xian-feng
XF
Zhi
Hui-ping
HP
Zhao
Yong
Y
Cao
Chun-yu
CY
Cui
Hai-feng
HF
Wang
Xiu-rong
XR
Zhang
Chun-ying
CY
D000368:Aged; D001809:Blood Viscosity / Q000187:drug effects; D015140:Dementia, Vascular / Q000097:blood / Q000188:drug therapy*; D004311:Double-Blind Method; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000627:therapeutic use*; D004903:Erythrocyte Aggregation / Q000187:drug effects; D004907:Erythrocyte Deformability / Q000187:drug effects; D006801:Humans; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D021641:Recognition, Psychology / Q000187:drug effects
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal