T-cell rich B-cell lymphoma--a case report.
T-Cell-Rich B-Cell lymphoma (TCRBCL) is a recently described variant of diffuse large B-cell lymphoma characterized by a predominance of reactive T-cells and a minority of neoplastic large cells which may resemble the Reed-Sternberg cell or its variants. TCRBCL is a notorious mimicker of both lymphocyte predominance Hodgkin's disease (LPHD) and peripheral T-cell lymphoma (PTCL). Immunohistochemistry is mandatory for a definitive diagnosis. We report a case of TCRBCL which was mistaken for HD both on fine needle aspiration cytology and histopathology due to the presence of RS like cells. Immunohistochemistry resolved the diagnostic dilemma.
Pai
Radha Ramachandra
RR
Department of Pathology, Kasturba Medical College, Mangalore, Karnataka. pairadharam@yahoo.co.in
Khadilkar
Urmila Niranjan
UN
Pai
Muktha Ramesh
MR
Dinesh
M
M
D000328:Adult; D015703:Antigens, CD / Q000378:metabolism; D003937:Diagnosis, Differential; D006689:Hodgkin Disease / Q000175:diagnosis; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology / Q000473:pathology*
D015703:Antigens, CD