Spleen volume and platelet number changes after living donor liver transplantation in adults.
OBJECTIVE
The purpose of the present study was to examine the changes of spleen volume and platelet numbers after living donor liver transplantation in adults.


METHODS
The spleen volume was measured by computed tomography preoperatively and 1, 6, and 12 months in 19 patients after liver transplantation. The platelet numbers were followed on the same time schedule.


RESULTS
The preoperative average spleen volume was 451+/-276 mL, which decreased gradually after liver transplantation. The preoperative averaged platelet number was 15.4+/-9.0x10(4)/mL, which did not change significantly during the observation period.


CONCLUSIONS
The changes in spleen volume in the present study were consistent with the previous data, suggesting that living donor liver transplantation effectively reduced hypersplenism for adult patients.
Kaneko
Junichi
J
Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan.
Sugawara
Yasuhiko
Y
Akamatsu
Nobuhisa
N
Kokudo
Norihiro
N
Makuuchi
Masatoshi
M
D000328:Adult; D015209:Cholangitis, Sclerosing / Q000601:surgery; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D011184:Postoperative Period; D013163:Splenomegaly / Q000097:blood