Successful CABG in a patient with paroxysmal nocturnal hemoglobinuria.
Paroxysmal nocturnal hemoglobinuria (PNH) is an uncommon acquired disorder of blood cells characterized by intravascular hemolysis due to an inordinate sensitivity to complement-mediated membrane damage. This report documents coronary artery revascularization in a patient with PNH, which has not been described in the literature so far. We used the on-pump procedure in the present patient and successfully performed revascularization by taking prophylactic measures against hemolysis.
Naito
Yuji
Y
Department of Cardiovascular Surgery, Yamanashi Central Hospital, 1-1-1, Fujimi, Kofu-shi, Yamanashi 400-0027, Japan. ujinaito@aol.com
Nakajima
Masato
M
Inoue
Hidenori
H
Tsuchiya
Koji
K
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D003911:Dextrans / Q000627:therapeutic use; D017707:Erythrocyte Transfusion; D006242:Haptoglobins / Q000627:therapeutic use; D006457:Hemoglobinuria, Paroxysmal / Q000150:complications*; D006461:Hemolysis; D006801:Humans; D007262:Infusions, Intravenous; D007387:Internal Mammary-Coronary Artery Anastomosis / Q000379:methods*; D008297:Male; D009204:Myocardial Revascularization
D000305:Adrenal Cortex Hormones; D000925:Anticoagulants; D003911:Dextrans; D006242:Haptoglobins