Synthesis of [323]-p-octiphenyls: orthogonal functionalization along a rigid-rod scaffold for refined supramolecular architecture.
[structure: see text] The synthesis of p-octiphenyls carrying orthogonal tert-butyl esters in the peripheral positions 1(2), 2(2), 3(3), 6(2), 7(3), and 8(2) and either p-methoxybenzyl or benzyl ester substituents in the central positions 4(2) and 5(3) is described. Resolution-enhanced HSQC/HMBC two-dimensional NMR spectroscopy is implemented as an attractive method for the complete characterization of complex p-oligophenyl scaffolds.
Ronan
Dawn
D
Department of Organic Chemistry, University of Geneva, Geneva, Switzerland.
Baudry
Yoann
Y
Jeannerat
Damien
D
Matile
Stefan
S