Modulation of taste peripheral signal through interpapillar inhibition in hamsters.
Single taste buds from fungiform papillae were iontophoretically stimulated with chemicals filling glass microelectrodes while a single unit was recorded in the taste pore of a neighbor papilla. High signal-to-noise ratio responses were observed in the recorded papilla as antidromic action potentials. These responses were possibly modulated by the simultaneous stimulation of another adjacent papilla. A decrease in the frequency of firing and/or both decrementing spikes were observed during such dual papillae stimulations. These inhibitory effects were not modified by the section of the chordo-lingual nerve, suggesting the tongue is able to process the gustatory information thanks to interpapillar negative feedback, prior to transmitting the signal to the central nervous system. Branched chorda tympani fibers can account for responses observed for single papillae stimulations; inhibitions and decrementing spikes may suggest the contribution of another mechanism of interaction between two different single fibers.
Vandenbeuch
Aurélie
A
CNRS, Laboratoire de Neurobiologie Sensorielle, Physiologie de la Manducation, Université Paris 7, 1 avenue des Olympiades, 91744 Massy Cedex, France. vandenbe@ccr.jussieu.fr
Pillias
Anne-Marie
AM
Faurion
Annick
A
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D002814:Chorda Tympani Nerve / Q000502:physiology; D006224:Cricetinae; D008036:Lingual Nerve / Q000502:physiology; D008297:Male; D009433:Neural Inhibition / Q000502:physiology*; D010525:Peripheral Nerves / Q000502:physiology*; D013649:Taste / Q000502:physiology; D013650:Taste Buds / Q000502:physiology*