title: [Neonatal thrombosis of the jugular veins: long-term repercussions on cerebral development (two cases)].
abstract: Bilateral obstruction of the internal jugular veins is rare in the neonatal period and no long-term follow-up has been reported yet. We report two cases. The first developped an extensive thrombosis of superior veina cava related to a central veinous line, the second an unilateral thrombosis of the transverse-sigmoid sinus associated to a constitutional hypoplasia of the contralateral jugular vein. In the latter case, no cause or risk factor was noticeable, except for a forceps delivery. In both cases the clinical course was dominated by the development of a prominent collateral network of cervico-facial veins and by a progressive macrocrania. According to MRImaging, the latter was not related to a dilation of CSF spaces, but to a macro-encephaly, either by inflation of the vascular veinous compartment inside the parenchyma or by genuine brain's overgrowth. Long-term follow-up showed a grossly normal course, both from the neurological and the scholar point of view. However, slight neuropsychological anomalies were noticed, bringing some shade on the prognosis.
authors.affiliation: Service de Pédiatrie à Orientation Neurologique, CHU Paris sud Bicêtre, Le Kremlin Bicêtre.
authors.forename: M
authors.initials: M
authors.lastname: N'Diaye
authors.forename: P
authors.initials: P
authors.lastname: Lasjaunias
authors.forename: B
authors.initials: B
authors.lastname: Husson
authors.forename: N
authors.initials: N
authors.lastname: Seibel
authors.forename: P
authors.initials: P
authors.lastname: Landrieu
mesh_terms: D001921:Brain / Q000254:growth & development*; D001927:Brain Diseases / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007601:Jugular Veins; D008297:Male; D013997:Time Factors; D020246:Venous Thrombosis / Q000150:complications*