Stereotyped behaviors or punding after quetiapine administration in Parkinson's disease.
Quetiapine has been suggested to be useful for the treatment of psychosis in patients with Parkinson's disease without prominent deterioration of motor functions. We present two patients with Parkinson's disease in whom administration of quetiapine for drug-induced psychosis caused characteristic stereotyped behaviors or punding. Since stereotyped behaviors are usually associated with excessive dopaminergic activity, it is clinically important to note that stereotyped behaviors or punding may be induced by an atypical antipsychotic drug for the treatment of psychosis in patients with Parkinson's disease.
Miwa
Hideto
H
Department of Neurology, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, Wakayama 641-8510, Japan. h-miwa@wakayama-med.ac.jp
Morita
Shuhei
S
Nakanishi
Ichiro
I
Kondo
Tomoyoshi
T
D000368:Aged; D003987:Dibenzothiazepines / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D000069348:Quetiapine Fumarate; D013239:Stereotyped Behavior / Q000187:drug effects* / Q000502:physiology
D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate