title: Rectal inflammation as first manifestation of graft-vs-host disease: radiologic-pathologic findings.
abstract: Graft-vs-host disease (GVHD) is a common, life-threatening complication of bone marrow transplantation that frequently involves the gastrointestinal tract. Since symptoms are typically nonspecific, radiologic examination is often performed to reach a diagnosis. To the best of our knowledge, this is the first reported radiologic description of a case of rectal involvement as the first manifestation of GVHD. The differential diagnosis of segmental rectal wall thickening in a patient following bone marrow transplantation should include GVHD.
authors.affiliation: Division of Abdominal Imaging and Intervention, Department of Radiology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
authors.forename: Vito
authors.initials: V
authors.lastname: Cantisani
authors.forename: Koenraad J
authors.initials: KJ
authors.lastname: Mortele
authors.forename: Salvatore G
authors.initials: SG
authors.lastname: Viscomi
authors.forename: Jonathan
authors.initials: J
authors.lastname: Glickman
authors.forename: Stuart G
authors.initials: SG
authors.lastname: Silverman
authors.forename: Pablo R
authors.initials: PR
authors.lastname: Ros
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D016026:Bone Marrow Transplantation / Q000009:adverse effects / Q000379:methods; D016572:Cyclosporine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006086:Graft vs Host Disease / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D009190:Myelodysplastic Syndromes / Q000175:diagnosis / Q000628:therapy; D011239:Prednisolone / Q000008:administration & dosage; D011349:Proctitis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology*; D012007:Rectum; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D016572:Cyclosporine; D011239:Prednisolone