title: Use of hypertonic saline in the treatment of cerebral edema in diabetic ketoacidosis (DKA).
abstract: Cerebral edema is the primary cause of morbidity and mortality in children and adolescents with diabetic ketoacidosis (DKA). We report a case of an adolescent female with life-threatening DKA-related cerebral edema who responded to a combination of mannitol and hypertonic saline. This is the first report of the use of hypertonic saline in the treatment of cerebral edema due to DKA.
authors.affiliation: Department of Pediatrics, Division of Endocrinology, The Hospital for Sick Children, The University of Toronto, Toronto, Ontario, Canada. Jacqueline.curtis@sickkids.on.ca
authors.forename: J R
authors.initials: JR
authors.lastname: Curtis
authors.forename: D
authors.initials: D
authors.lastname: Bohn
authors.forename: D
authors.initials: D
authors.lastname: Daneman