title: Effectiveness of cardiac surgery in trisomies 13 and 18 (from the Pediatric Cardiac Care Consortium).
abstract: Because of severely reduced lifespan in children with trisomies 13 and 18, surgical repair of congenital heart lesions has rarely been offered. With data from a multicenter registry, we report 35 cases of cardiac surgery in infants and children with trisomy 13 or 18 with a 91% hospital survival rate. Those patients without an extended preoperative ventilatory requirement did not require prolonged mechanical ventilation after surgery.
authors.affiliation: Division of Pediatric Cardiology, Charleston, South Carolina 29425, USA. atzam@musc.edu
authors.forename: Eric M
authors.initials: EM
authors.lastname: Graham
authors.forename: Scott M
authors.initials: SM
authors.lastname: Bradley
authors.forename: Girish S
authors.initials: GS
authors.lastname: Shirali
authors.forename: Christine B
authors.initials: CB
authors.lastname: Hills
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Atz
mesh_terms: D002170:Canada / Q000453:epidemiology; D006348:Cardiac Surgical Procedures / Q000706:statistics & numerical data; D002648:Child; D002675:Child, Preschool; D002882:Chromosomes, Human, Pair 13; D002887:Chromosomes, Human, Pair 18; D005060:Europe / Q000453:epidemiology; D005260:Female; D006330:Heart Defects, Congenital / Q000401:mortality* / Q000601:surgery*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011183:Postoperative Complications; D012042:Registries; D012121:Respiration, Artificial; D012189:Retrospective Studies; D016019:Survival Analysis; D014314:Trisomy; D014481:United States / Q000453:epidemiology