title: The Toll-like receptor 4 Asp299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome.
authors.affiliation: University Medical Center Nijmegen, Nijmegen, The Netherlands.
authors.forename: Timothy R D J
authors.initials: TR
authors.lastname: Radstake
authors.forename: Barbara
authors.initials: B
authors.lastname: Franke
authors.forename: Suzanne
authors.initials: S
authors.lastname: Hanssen
authors.forename: Mihai G
authors.initials: MG
authors.lastname: Netea
authors.forename: Paco
authors.initials: P
authors.lastname: Welsing
authors.forename: Pilar
authors.initials: P
authors.lastname: Barrera
authors.forename: Leo A B
authors.initials: LA
authors.lastname: Joosten
authors.forename: Piet L C M
authors.initials: PL
authors.lastname: van Riel
authors.forename: Wim B
authors.initials: WB
authors.lastname: van den Berg
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging / Q000235:genetics* / Q000503:physiopathology*; D001224:Aspartic Acid / Q000235:genetics; D016022:Case-Control Studies; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D014644:Genetic Variation; D005838:Genotype; D005998:Glycine / Q000235:genetics; D006801:Humans; D008297:Male; D008562:Membrane Glycoproteins / Q000235:genetics*; D008875:Middle Aged; D010641:Phenotype; D011110:Polymorphism, Genetic; D011859:Radiography; D011956:Receptors, Cell Surface / Q000235:genetics*; D012720:Severity of Illness Index; D051197:Toll-Like Receptor 4; D051193:Toll-Like Receptors
chemical_list: D008562:Membrane Glycoproteins; D011956:Receptors, Cell Surface; C495345:TLR4 protein, human; D051197:Toll-Like Receptor 4; D051193:Toll-Like Receptors; D001224:Aspartic Acid; D005998:Glycine