title: [Allergy to house dust mites: allergy independent symptoms dominate].
abstract: A sensitisation to allergens has not always a clinical relevance. Therefore, the history has an uppermost importance for defining the relevance of a sensitisation. In contrast to the history in seasonal rhino-conjunctivitis, which causes typical complains in a restricted time period patients with house dust mite allergy seem to have less defined complaints. To define the most relevant symptoms of this frequent allergy, we evaluated 35 patients with clearly defined house dust mite allergy by a questionnaire and evaluated the same questionnaire also in a control group of 18 patients without sensitisation or asthma. The symptoms described in the patient group confirm that symptoms of house dust mite allergy are frequently not related to a direct allergen exposure. Some patients complained about itchy red eyes in the morning, but the majority of symptoms occurred independent from allergen exposure. These are blocked nose as well as exercise induced asthma. These symptoms are present all year around and are not only restricted to mite exposed areas. They are probably related to the underling eosinophilic inflammation. Thus exercise induced asthma and blocked nose are symptoms, which may indicate a mite allergy, particular in younger patients.
authors.affiliation: Allergologisch-Immunologische Poliklinik, Klinik für Rheumatologie, Klinische Immunologie/Allergologie, Inselspital Bern.
authors.forename: L M
authors.initials: LM
authors.lastname: Herwig
authors.forename: A
authors.initials: A
authors.lastname: Helbling
authors.forename: W J
authors.initials: WJ
authors.lastname: Pichler
authors.forename: C E
authors.initials: CE
authors.lastname: Pichler
mesh_terms: D000293:Adolescent; D000328:Adult; D039741:Antigens, Dermatophagoides / Q000276:immunology; D001249:Asthma / Q000175:diagnosis* / Q000276:immunology; D002648:Child; D003233:Conjunctivitis, Allergic / Q000175:diagnosis* / Q000276:immunology; D003876:Dermatitis, Atopic / Q000175:diagnosis* / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007428:Intradermal Tests; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D039981:Pyroglyphidae / Q000276:immunology*; D012221:Rhinitis, Allergic, Perennial / Q000175:diagnosis* / Q000276:immunology
chemical_list: D039741:Antigens, Dermatophagoides; D007073:Immunoglobulin E