title: Human exposure to polychlorinated diphenyl ethers through the diet in Catalonia, Spain.
abstract: Although polychlorinated diphenyl ethers (PCDEs) are recognized environmental pollutants, information concerning human exposure to these organic substances is very scarce. For the present study the concentrations of PCDEs in a number of foodstuffs acquired in Catalonia, Spain, were determined. The dietary intake of PCDEs was estimated for various age groups of the general population living in this Spanish region. With the exception of fish and shellfish, PCDE concentrations were under the limit of detection in the 10 remaining food groups analyzed. For an adult (20-65 years old) male of 70 kg average body weight, the estimated total dietary intake of PCDEs was 41 ng/day. It was assumed that if a PCDE congener was below the detection limit, the concentration was equal to half of the limit of detection. The highest exposure to PCDEs through the diet corresponded to the group aged 51-65 years, whereas the lowest intake corresponded to the youngest group (4-9 years). With the exception of the group aged >65 years, PCDE intake was always higher in males than in females. The results of this study should be of interest for future assessments of time trends in human exposure to PCDEs through the diet.
authors.affiliation: Laboratory of Toxicology and Environmental Health, School of Medicine, "Rovira i Virgili" University, San Lorenzo 21, 43201 Reus, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Bocio
authors.forename: Juan M
authors.initials: JM
authors.lastname: Llobet
authors.forename: Jose L
authors.initials: JL
authors.lastname: Domingo
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D002648:Child; D002675:Child, Preschool; D004032:Diet; D004781:Environmental Exposure; D005260:Female; D005399:Fishes; D055768:Halogenated Diphenyl Ethers; D006801:Humans; D008297:Male; D008875:Middle Aged; D010647:Phenyl Ethers / Q000008:administration & dosage*; D012758:Shellfish / Q000032:analysis; D013030:Spain
chemical_list: D055768:Halogenated Diphenyl Ethers; D010647:Phenyl Ethers; C021244:polychlorinated diphenyl ethers