title: Susceptibility testing of Singapore strains of Mycoplasma hominis to tetracycline, gatifloxacin, moxifloxacin, ciprofloxacin, clindamycin, and azithromycin by the Etest method.
abstract: The minimal inhibitory concentrations of tetracycline, gatifloxacin, moxifloxacin, ciprofloxacin, clindamycin and azithromycin for 28 Singapore clinical Mycoplasma hominis strains were studied using the Etest method. Different incubation conditions did not affect susceptibility categories, except for tetracycline intermediate-susceptibility strains. Tetracycline-susceptibility was only 35.7%. All strains were susceptible to the fluoroquinolones and clindamycin but resistant to azithromycin.
authors.affiliation: Department of Pathology, Singapore General Hospital, Singapore 169608, Singapore. gptncl@sgh.com.sg
authors.forename: Cecilia C L
authors.initials: CC
authors.lastname: Ngan
authors.forename: Tongying
authors.initials: T
authors.lastname: Lim
authors.forename: Chin-Mun
authors.initials: CM
authors.lastname: Choo
authors.forename: Grace L-X
authors.initials: GL
authors.lastname: Toh
authors.forename: Yok-Seng
authors.initials: YS
authors.lastname: Lim
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001372:Aza Compounds / Q000494:pharmacology; D017963:Azithromycin / Q000494:pharmacology; D002939:Ciprofloxacin / Q000494:pharmacology; D002981:Clindamycin / Q000494:pharmacology; D024901:Drug Resistance, Multiple, Bacterial; D024841:Fluoroquinolones / Q000494:pharmacology*; D000077734:Gatifloxacin; D006801:Humans; D008826:Microbial Sensitivity Tests; D000077266:Moxifloxacin; D019535:Mycoplasma hominis / Q000145:classification / Q000187:drug effects*; D011804:Quinolines / Q000494:pharmacology; D012494:Sampling Studies; D012680:Sensitivity and Specificity; D012846:Singapore; D013752:Tetracycline / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D001372:Aza Compounds; D024841:Fluoroquinolones; D011804:Quinolines; D002981:Clindamycin; D002939:Ciprofloxacin; D017963:Azithromycin; D013752:Tetracycline; D000077734:Gatifloxacin; D000077266:Moxifloxacin