[The relationship between the protection of ginsenoside for spinal cell and nitric oxide].
OBJECTIVE
To study the relationship between the protection of Ginsenoside(GS) for spinal cells and nitric oxide (NO).


METHODS
Spinal cells were cultured in vitro, the model of peripheral nerve was established by scarifying the cells, and NO was measured by Griess method.


RESULTS
NO in injury group was high than that in noninjury group and NO in group cultured by GS was less than that in group cultured by common medium.


CONCLUSIONS
NO increases when peripheral nerve is injuried, and the protective effect of GS on spinal cells may be through inhibiting NO release.
Pan
Shu-yi
SY
Center of Army Hyperbaric Oxygen, General Navy Hospital, Beijing 100037, China.
Pan
Xiao-wen
XW
Wang
Su-ping
SP
D000818:Animals; D002478:Cells, Cultured; D005333:Fetus; D036145:Ginsenosides / Q000302:isolation & purification / Q000494:pharmacology*; D009046:Motor Neurons / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D009475:Neurons, Afferent / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D018696:Neuroprotective Agents / Q000494:pharmacology*; D009569:Nitric Oxide / Q000378:metabolism*; D005894:Panax / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D017207:Rats, Sprague-Dawley; D013116:Spinal Cord / Q000166:cytology / Q000378:metabolism*
D036145:Ginsenosides; D018696:Neuroprotective Agents; D009569:Nitric Oxide; C035054:ginsenoside Rg1