title: Synthesis of phosphaisocoumarins via iodocyclization.
abstract: 4-Iodophosphaisocoumarins can be prepared in good yield and with high regioselectivity under mild conditions by the reaction of o-(1-alkynyl)phenylphosphonates with I(2) or ICl. The present reaction represents the first example of a phosphonate iodocyclization onto a C-C triple bond. The resulting iodides can be further elaborated using palladium-catalyzed coupling reactions.
authors.affiliation: Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China.
authors.forename: Ai-Yun
authors.initials: AY
authors.lastname: Peng
authors.forename: Yi-Xiang
authors.initials: YX
authors.lastname: Ding