Platinum(II)-bis(9-methyladenine) complexes; N1-->N6 migration of Pt(II)vs deamination of coordinated methyladenine.
Stepwise migration of coordinated Pt(II) from the endocyclic N1 site to the exocyclic amino group occurs in the bis(9-methyladenine-N1) complex of cis-Pt(II)(NH(3))(2) in basic solution, whereafter deamination of the 9-methyladenine still coordinated at N-1 competes with a second migration step.
Klika
Karel D
KD
Department of Chemistry, University of Turku, FIN-20014 Turku, Finland. karel.klika@utu.fi
Arpalahti
Jorma
J
D000225:Adenine / Q000031:analogs & derivatives* / Q000737:chemistry*; D003641:Deamination; D015394:Molecular Structure; D009944:Organoplatinum Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010984:Platinum / Q000737:chemistry*
D009944:Organoplatinum Compounds; D010984:Platinum; C013115:9-methyladenine; D000225:Adenine