title: Micro-geographical differentiation in Northern Iberia revealed by Y-chromosomal DNA analysis.
abstract: Y-chromosome diversity has been analyzed at a micro-geographical level, examining 10 binary polymorphisms and 7 short tandem repeats (STRs) in 443 samples belonging to 11 populations from two regions of Northern Spain, Galicia and Cantabria. Both regions, as a whole, cluster with other Iberian populations. However, some individual populations, particularly that from the Pas Valley in Cantabria, depart markedly from this general pattern, with higher genetic distances and reduced diversity. This unusual population is even more distinct than the Basques from their Iberian neighbors. Genetic drift in a small isolated population could explain this special behavior, and in addition to its anthropological interest, this finding has important forensic implications.
authors.affiliation: Institute of Legal Medicine, University of Santiago de Compostela, San Francisco s/n., 15782 Santiago de Compostela, Spain.
authors.forename: María
authors.initials: M
authors.lastname: Brion
authors.forename: Bea
authors.initials: B
authors.lastname: Quintans
authors.forename: Maite
authors.initials: M
authors.lastname: Zarrabeitia
authors.forename: Anna
authors.initials: A
authors.lastname: Gonzalez-Neira
authors.forename: Antonio
authors.initials: A
authors.lastname: Salas
authors.forename: Victoria
authors.initials: V
authors.lastname: Lareu
authors.forename: Chris
authors.initials: C
authors.lastname: Tyler-Smith
authors.forename: Angel
authors.initials: A
authors.lastname: Carracedo
mesh_terms: D041322:Chromosomes, Human, Y / Q000235:genetics*; D004247:DNA / Q000032:analysis*; D005819:Genetic Markers / Q000235:genetics; D014644:Genetic Variation; D005828:Genetics, Population; D005843:Geography; D006239:Haplotypes; D006801:Humans; D008297:Male; D010802:Phylogeny; D013030:Spain
chemical_list: D005819:Genetic Markers; D004247:DNA