title: Causes of death within 1 year of resection for lung cancer. Early mortality after resection.
abstract: OBJECTIVE
  Some of the lung cancer patients who are treated surgically with curative intent ultimately die in the early postoperative period. The aim of this study is to analyze the causes of death within 1 year of resection for lung cancer in our patients.
  
  
  METHODS
  Six hundred and twenty patients, who underwent resection for lung cancer with a curative intent were reviewed retrospectively. Eighteen patients (2.9%) died due to postoperative complications or within the first month and 51 (8.4%) patients (group 1) died within the first year after operation. Fifty-one patients (group 1) were compared with the survivors (group 2) in terms of age, gender, preoperative FEV 1, pathological tumor node metastasis (TNM), histopathological subtypes, type of resection, completeness of the resection, preoperative Karnofsky performance status and application of postoperative radiotherapy.
  
  
  RESULTS
  Pathological TNM (P<0.001) type of resection (P<0.01) histopathological subtype (P<0.001) completeness of the resection (P<0.05) and postoperative radiotherapy (P<0.001) were determined to be significant factors in mortality within 1 year after resection for lung cancer.
  
  
  CONCLUSIONS
  The patients with pathological stage 3 disease, with large cell histology or who had undergone pneumonectomy have a higher risk of mortality within 1 year. These patients require detailed preoperative work up in terms of metastatic disease and cardiopulmonary physiological status.
authors.affiliation: Department of Thoracic Surgery, Istanbul Medical School, Istanbul University, Istanbul, Turkey.
authors.forename: Alper
authors.initials: A
authors.lastname: Toker
authors.forename: Sukru
authors.initials: S
authors.lastname: Dilege
authors.forename: Sedat
authors.initials: S
authors.lastname: Ziyade
authors.forename: Osman
authors.initials: O
authors.lastname: Eroglu
authors.forename: Serhan
authors.initials: S
authors.lastname: Tanju
authors.forename: Dilek
authors.initials: D
authors.lastname: Yilmazbayhan
authors.forename: Zeki
authors.initials: Z
authors.lastname: Kilicarslan
authors.forename: Goksel
authors.initials: G
authors.lastname: Kalayci
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality* / Q000532:radiotherapy / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011013:Pneumonectomy / Q000379:methods; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis; D016896:Treatment Outcome