Identification of palytoxin as a principle which causes morphological changes in rat 3Y1 cells in the zoanthid Palythoa aff. margaritae.
A very potent cell-bursting principle was isolated from the extract of the zoanthid Palythoa aff. margaritae. The compound was identified as palytoxin by comparing the spectral data and HPLC profile with those of an authentic sample.
Oku
Naoya
N
Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Sata
Noriko U
NU
Matsunaga
Shigeki
S
Uchida
Hiro'omi
H
Fusetani
Nobuhiro
N
D000178:Acrylamides / Q000302:isolation & purification* / Q000633:toxicity*; D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D002478:Cells, Cultured; D002851:Chromatography, High Pressure Liquid; D003064:Cnidarian Venoms / Q000302:isolation & purification* / Q000633:toxicity*; D005347:Fibroblasts / Q000187:drug effects*; D051381:Rats; D000095702:Polyether Toxins
D000178:Acrylamides; D003064:Cnidarian Venoms; C010272:palytoxin; D000095702:Polyether Toxins