Single-site modifications and their effect on the folding stability of m-phenylene ethynylene oligomers.
[reaction: see text] The folded structure of a m-phenylene ethynylene oligomer is tolerant to single-site modifications to both the backbone sequence and end groups. The helical structure is reinforced by multiple noncovalent interactions, allowing the oligomer sequence to be customized without a significant change in stability in most cases. The small changes that are observed are consistent with the expected behavior of pi-stacked systems and demonstrate subtle control over folding through single-site modifications.
Goto
Hirofumi
H
Department of Chemistry and Materials Science & Engineering, 600 South Mathews Avenue, The University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Heemstra
Jennifer M
JM
Hill
David J
DJ
Moore
Jeffrey S
JS