Antigenic secreted proteins from Haemophilus paragallinarum. A 110-kDa putative RTX protein.
Haemophilus paragallinarum is the causal agent of infectious coryza, an economically important disease for the poultry industry. This bacterium secreted proteins of 25-110 kDa during its growth in brain heart infusion, tryptic soy broth, or Luria-Bertani glucose phosphate media, all lacking serum. Some of these proteins were recognized by sera from chickens experimentally infected with H. paragallinarum. A 110-kDa protein was recognized by a serum pool from convalescent-phase pigs naturally infected with Actinobacillus pleuropneumoniae, and also by a rabbit polyclonal serum against Apx I as well as a rabbit serum against Mannheimia haemolytica leukotoxin, suggesting the presence of an RTX-like protein in H. paragallinarum. H. paragallinarum secreted proteins could be important immunogens in the control of infectious coryza.
Mena-Rojas
Erika
E
Centro de Investigaciones en Ciencias Microbiológicas, BUAP, Apdo. Postal 1622, Puebla 72560, Mexico.
Vázquez Cruz
Candelario
C
Vaca Pacheco
Sergio
S
García González
Octavio
O
Pérez-Márquez
Víctor M
VM
Pérez-Méndez
Alma
A
Ibarra-Caballero
Jorge
J
de la Garza
Mireya
M
Zenteno
Edgar
E
Negrete-Abascal
Erasmo
E
D000189:Actinobacillus Infections / Q000276:immunology / Q000382:microbiology / Q000662:veterinary; D016977:Actinobacillus pleuropneumoniae / Q000276:immunology; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D000942:Antigens, Bacterial / Q000276:immunology* / Q000378:metabolism; D001426:Bacterial Proteins / Q000276:immunology* / Q000378:metabolism; D015153:Blotting, Western; D002645:Chickens / Q000276:immunology; D003429:Cross Reactions; D003470:Culture Media; D005098:Exotoxins / Q000276:immunology; D006192:Haemophilus Infections / Q000276:immunology / Q000382:microbiology / Q000662:veterinary; D044134:Haemophilus paragallinarum / Q000254:growth & development / Q000276:immunology* / Q000378:metabolism*; D016978:Mannheimia haemolytica / Q000276:immunology; D008970:Molecular Weight; D016871:Pasteurellaceae Infections / Q000276:immunology / Q000662:veterinary; D011201:Poultry Diseases / Q000276:immunology; D011817:Rabbits / Q000276:immunology; D013552:Swine / Q000276:immunology; D013553:Swine Diseases / Q000276:immunology
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D003470:Culture Media; D005098:Exotoxins; C018579:leukotoxin