title: Relationships between diurnal blood pressure variation, physical activity, and health-related QOL.
abstract: The aim of this study is to clarify the associations between diurnal blood pressure variation, physical activity and health-related quality of life (HRQOL). Ninety-seven volunteers, including 52 hypertensive patients and 45 healthy subjects (average age, 48 years) participated in this study. Twenty-four hour ambulatory blood pressure and heart rate variability were measured using TM2425 (A&D Co). Physical activity was measured using actigraphy, and HRQOL was assessed by a Medical Outcome Study Short-Forum 36-Item Health Survey (SF-36). Awake mean physical activity positively correlated with the nocturnal dip in systolic blood pressure (SBP) (r = 0.242, p < 0.02) and diastolic blood pressure (DBP) (r = 0.219, p < 0.04). The score of physical functioning positively correlated with awake mean physical activity (r = 0.265, p < 0.02). The score of role-emotional also correlated with awake mean physical activity (r = 0.269, p = 0.01). Using multiple regression analysis, the nocturnal dip in SBP was found to be correlated with awake and sleep mean physical activities (p < 0.05, p < 0.05, respectively). In conclusion, physical activity is associated with the nocturnal dip in blood pressure. Moreover, physical activity correlates with some of the factors of HRQOL.
authors.affiliation: Second Department of Internal Medicine, Yokohama City University School of Medicine, Yokohama City, Japan.
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Okano
authors.forename: Nobuhito
authors.initials: N
authors.lastname: Hirawa
authors.forename: Osamu
authors.initials: O
authors.lastname: Tochikubo
authors.forename: Shunsaku
authors.initials: S
authors.lastname: Mizushima
authors.forename: Shunichi
authors.initials: S
authors.lastname: Fukuhara
authors.forename: Minoru
authors.initials: M
authors.lastname: Kihara
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Toya
authors.forename: Satoshi
authors.initials: S
authors.lastname: Umemura
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000502:physiology; D018660:Blood Pressure Monitoring, Ambulatory; D016022:Case-Control Studies; D002940:Circadian Rhythm; D003971:Diastole; D005260:Female; D006304:Health Status; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D011788:Quality of Life; D013599:Systole