title: Facile quantification of enantiomeric excess and concentration with indicator-displacement assays: an example in the analyses of alpha-hydroxyacids.
abstract: An enantioselective indicator-displacement assay was developed to determine enantiomeric excess (ee) and concentration of alpha-hydroxyacid samples with two independent absorption measurements. The inherent relationship between the absorbance of the indicator-displacement ensemble and the overall concentration and ee of the analyte was established through solution equilibria.
authors.affiliation: Department of Chemistry and Biochemistry, The University of Texas at Austin, Austin, Texas 78712, USA.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhu
authors.forename: Eric V
authors.initials: EV
authors.lastname: Anslyn
mesh_terms: D002384:Catalysis; D006880:Hydroxy Acids / Q000737:chemistry*; D007700:Kinetics; D008956:Models, Chemical; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D006880:Hydroxy Acids