How do neutrophils and pathogens interact?
Many pathogens can manipulate macrophages after phagocytosis yet are efficiently killed by neutrophils. This poses the question of whether neutrophils have mechanisms that enable them to specifically recognise pathogens and have pathogens evolved mechanisms to modulate neutrophil function? Here, we review recent work on neutrophils and their interaction with four different bacteria: Staphylococcus aureus, Helicobacter pylori, Anaplasma phagocytophilum and members of the Enterobacteriae family.
Mayer-Scholl
Anne
A
Department for Cellular Microbiology, Max-Planck Institute for Infection Biology, Schumannstr. 21/22, 10117 Berlin, Germany. zychlinsky@mpiib-berlin.mpg.de
Averhoff
Petra
P
Zychlinsky
Arturo
A
D000818:Animals; D004755:Enterobacteriaceae / Q000276:immunology*; D004756:Enterobacteriaceae Infections / Q000276:immunology* / Q000382:microbiology*; D006790:Host-Parasite Interactions / Q000276:immunology; D006801:Humans; D009504:Neutrophils / Q000276:immunology* / Q000382:microbiology*