Possible central nervous system infection by SARS coronavirus.
On day 22 of illness, generalized tonic-clonic convulsion developed in a 32-year-old woman with severe acute respiratory syndrome (SARS). Cerebrospinal fluid tested positive for SARS coronavirus (SARS-CoV) by reverse transcriptase-polymerase chain reaction. SARS-CoV may have caused an infection in the central nervous system in this patient.
Lau
Kwok-Kwong
KK
Department of Medicine and Geriatrics, Princess Margaret Hospital, Kwai Chung, Hong Kong Special Administrative Region, China. dominickklau@hotmail.com
Yu
Wai-Cho
WC
Chu
Chung-Ming
CM
Lau
Suet-Ting
ST
Sheng
Bun
B
Yuen
Kwok-Yuen
KY
D058186:Acute Kidney Injury / Q000150:complications; D000328:Adult; D002494:Central Nervous System Infections / Q000150:complications* / Q000175:diagnosis / Q000821:virology; D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000821:virology; D020133:Reverse Transcriptase Polymerase Chain Reaction; D045473:Severe acute respiratory syndrome-related coronavirus / Q000235:genetics / Q000302:isolation & purification; D045169:Severe Acute Respiratory Syndrome / Q000150:complications* / Q000821:virology