[Intravitreal injection of triamcinolone acetonide for cystoid macular edema resistant to vitreous surgery].
OBJECTIVE
To report the efficacy of intravitreal injection of triamcinolone acetonide(TA) for cystoid macular edema remaining after vitreous surgery.


METHODS
Eight eyes of 7 patients aged from 32 to 84 years old were studied. The original diseases that caused macular edema were central retinal vein occlusion in 2 eyes, branch retinal vein occlusion in one eye, Irvine-Gass syndrome in 2 eyes, and diabetic retinopathy in 3 eyes. 4 mg of TA was injected intravitreally and visual acuity and foveal thickness measured by optical coherence tomography(OCT) were evaluated in before and after the surgery.


RESULTS
Macular edema resolved rapidly after injection of TA in all cases and cysts were extinguished or diminished. The foveal thickness in OCT was reduced significantly from preoperative 495 +/- 116 (mean +/- standard deviation) microns to 267 +/- 117 microns after one week, and 246 +/- 81 microns after one month. The effect persisted for three months. Visual improvement of more than two Snellen lines was seen in 4 eyes. No side effects were observed except a temporary increase of intraocular pressure in one eye.


CONCLUSIONS
Intravitreal injection of TA is effective in a short-term for cystoid macular edema remaining after vitrectomy.
Inoue
Makoto
M
Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Nagai
Norihiro
N
Shinoda
Hajime
H
Shinoda
Kei
K
Kitamura
Shizuaki
S
Oguchi
Yoshihisa
Y
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008269:Macular Edema / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D014222:Triamcinolone Acetonide / Q000008:administration & dosage / Q000627:therapeutic use*; D014821:Vitrectomy; D014822:Vitreous Body
D014222:Triamcinolone Acetonide