Role of CO(2) pneumoperitoneum-induced acidosis in CO(2) pneumoperitoneum-enhanced adhesion formation in mice.
The effect of assisted ventilation and CO(2) pneumoperitoneum during laparoscopic surgery upon blood gases and adhesion formation were evaluated in mice. We confirmed that the CO(2) pneumoperitoneum induces acidosis and enhances adhesion formation, and an association between both effects was demonstrated, together with its modulation by the assisted ventilation.
Molinas
Carlos Roger
CR
Tjwa
Marc
M
Vanacker
Bernard
B
Binda
Maria Mercedes
MM
Elkelani
Osama
O
Koninckx
Philippe Robert
PR
D000138:Acidosis / Q000139:chemically induced* / Q000150:complications*; D000818:Animals; D002245:Carbon Dioxide / Q000009:adverse effects*; D005260:Female; D051379:Mice; D011027:Pneumoperitoneum; D000267:Tissue Adhesions / Q000209:etiology*
D002245:Carbon Dioxide