Full orthogonality between Dde and Fmoc: the direct synthesis of PNA--peptide conjugates.
New deprotection conditions for the Dde amine protecting group that are fully orthogonal to Fmoc are described and successfully applied to the dual synthesis of PNA-peptide conjugates.
Díaz-Mochón
Juan Jose
JJ
School of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.
Bialy
Laurent
L
Bradley
Mark
M