title: [Immunological rapid urease test].
abstract: Immunological rapid urease test for detection of Helicobacter pylori infection, composed of a solid-phase tip coated with monoclonal antibody against H. pylori's urease and ion-sensitive field transistor (ISFT)-based pH sensor system, was developed. The monoclonal antibody against H. pylori's urease was useful to avoid the contamination of urease activity in other bacteria. Because ISFTT had high ability to detect pH change, the sensitivity and specificity of immunological rapid urease test was significantly improved comparing with that of conventional rapid urease test. The utility of immunological rapid urease test was evaluated in some clinical studies.
authors.affiliation: Department of Endoscopy, Hokkaido University Hospital.
authors.forename: Mototsugu
authors.initials: M
authors.lastname: Kato
authors.forename: Soichi
authors.initials: S
authors.lastname: Nakagawa
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Shimizu
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yuki
authors.forename: Nozomu
authors.initials: N
authors.lastname: Fuse
authors.forename: Masaaki
authors.initials: M
authors.lastname: Takei
authors.forename: Shigeru
authors.initials: S
authors.lastname: Furukawa
authors.forename: L A
authors.initials: LA
authors.lastname: Perez-Aldana
authors.forename: Zheng
authors.initials: Z
authors.lastname: Rinan
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Komatsu
authors.forename: Nagahito
authors.initials: N
authors.lastname: Saito
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takeda
authors.forename: Toshiro
authors.initials: T
authors.lastname: Sugiyama
authors.forename: Masahiro
authors.initials: M
authors.lastname: Asaka
mesh_terms: D000911:Antibodies, Monoclonal; D005750:Gastric Juice; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000201:enzymology*; D006801:Humans; D012680:Sensitivity and Specificity; D014510:Urease / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D014510:Urease