RNA conformational classes.
RNA exhibits a large diversity of conformations. Three thousand nucleotides of 23S and 5S ribosomal RNA from a structure of the large ribosomal subunit were analyzed in order to classify their conformations. Fourier averaging of the six 3D distributions of torsion angles and analyses of the resulting pseudo electron maps, followed by clustering of the preferred combinations of torsion angles were performed on this dataset. Eighteen non-A-type conformations and 14 A-RNA related conformations were discovered and their torsion angles were determined; their Cartesian coordinates are available.
Schneider
Bohdan
B
Center for Complex Molecular Systems and Biomolecules and Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo n.2, CZ-16610 Prague, Czech Republic. bohdan@uochb.cas.cz
Morávek
Zdenek
Z
Berman
Helen M
HM
D008958:Models, Molecular; D015394:Molecular Structure; D009690:Nucleic Acid Conformation; D012335:RNA, Ribosomal / Q000737:chemistry* / Q000145:classification; D012338:RNA, Ribosomal, 23S / Q000737:chemistry; D012341:RNA, Ribosomal, 5S / Q000737:chemistry
D012335:RNA, Ribosomal; D012338:RNA, Ribosomal, 23S; D012341:RNA, Ribosomal, 5S