A new synthetic route to nucleosides: dissymmetric construction of a cyclopentene system by double [3,3]-sigmatropic rearrangement and double ring-closing metathesis.
[reaction: see text] The dissymmetric synthesis of a carbocyclic nucleoside was achieved by a novel double [3,3]-sigmatropic rearrangement/double ring-closing metathesis strategy with a high stereoselectivity.
Fang
Zhe
Z
College of Pharmacy, Chosun University, Kwangju 501-759, Republic of Korea.
Hong
Joon Hee
JH
D003517:Cyclopentanes / Q000737:chemistry*; D007202:Indicators and Reagents; D015394:Molecular Structure; D009705:Nucleosides / Q000138:chemical synthesis*
D003517:Cyclopentanes; D007202:Indicators and Reagents; D009705:Nucleosides