title: Comparison of the lipid profile, blood pressure, and dietary habits of adolescents and children descended from hypertensive and normotensive individuals.
abstract: OBJECTIVE
  To compare blood pressure, lipid profile, food intake, and anthropometric data of adolescents with or without a familial history of hypertension.
  
  
  METHODS
  Forty-three adolescents from both sexes were assessed, with ages ranging from 11 to 18 years old. Twenty had hypertensive parents, and 23 had normotensive parents. The following variables were examined: blood pressure, food intake, anthropometric data, lipid profile, and the results of following dietary guidelines (American Heart Association).
  
  
  RESULTS
  The offspring of hypertensive parents had greater baseline systolic blood pressure (109 +/- 3 vs. 99 +/- 2 mm Hg, P=0.01), diastolic blood pressure (68 +/- 2 vs. 62 +/- 2 mm Hg, p=0.04), greater TC/HDL-C ratio (4.1 +/- 0.3 vs. 3.2 +/- 0.2, P<0.01), and greater LDL/HDL-C (2.7 +/- 0.2 vs. 1.9 +/- 0.1, P<0.01), and smaller values of HDL-C (43 +/- 2 vs.53 +/- 2 mg/dL, P<0.005). Dietary intake and anthropometric measures assessed did not differ between the groups. Even though dietary intervention resulted in reductions in body mass index (21.0+/- 1.2 vs. 20.1 +/- 1.1 kg/m(2), P<0.01), it did not change dyslipidemia present in the offspring of hypertensive individuals.
  
  
  CONCLUSIONS
  Increased blood pressure levels and less favorable lipid profiles are found among offspring of hypertensive parents, where low levels of HDL-C were the most relevant finding regardless of anthropometric or nutritional variables.
authors.affiliation: Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Elias
authors.forename: Max Samuel Mattos
authors.initials: MS
authors.lastname: Bolívar
authors.forename: Francisco Antonio Helfenstein
authors.initials: FA
authors.lastname: Fonseca
authors.forename: Tania Leme da Rocha
authors.initials: TL
authors.lastname: Martinez
authors.forename: Japy
authors.initials: J
authors.lastname: Angelini
authors.forename: Celso
authors.initials: C
authors.lastname: Ferreira
authors.forename: Nelson
authors.initials: N
authors.lastname: Kasinski
authors.forename: Angelo Amato Vincenzo
authors.initials: AA
authors.lastname: de Paola
authors.forename: Antonio Carlos Camargo
authors.initials: AC
authors.lastname: Carvalho
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000886:Anthropometry; D001794:Blood Pressure / Q000502:physiology*; D002648:Child; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D006973:Hypertension / Q000235:genetics* / Q000378:metabolism / Q000503:physiopathology; D008055:Lipids / Q000097:blood*; D012307:Risk Factors
chemical_list: D008055:Lipids