Expression failure of the Notch signaling system is associated with the pathogenesis of maturation arrest in male infertility patients.
The receptor or ligand of the Notch signaling system fails to express in the germ cells of maturation arrest patients, indicating that this signaling system is associated with for the pathogenesis of maturation arrest.
Hayashi
Tetsuo
T
Yamada
Takumi
T
Kageyama
Yukio
Y
Negishi
Takeharu
T
Kihara
Kazunori
K
D000328:Adult; D000368:Aged; D016922:Cellular Senescence; D006801:Humans; D007248:Infertility, Male / Q000503:physiopathology*; D008297:Male; D008565:Membrane Proteins / Q000172:deficiency* / Q000378:metabolism; D008875:Middle Aged; D051880:Receptors, Notch; D015398:Signal Transduction; D013094:Spermatozoa
D008565:Membrane Proteins; D051880:Receptors, Notch