Comparison of the lipid profile, blood pressure, and dietary habits of adolescents and children descended from hypertensive and normotensive individuals.
OBJECTIVE
To compare blood pressure, lipid profile, food intake, and anthropometric data of adolescents with or without a familial history of hypertension.


METHODS
Forty-three adolescents from both sexes were assessed, with ages ranging from 11 to 18 years old. Twenty had hypertensive parents, and 23 had normotensive parents. The following variables were examined: blood pressure, food intake, anthropometric data, lipid profile, and the results of following dietary guidelines (American Heart Association).


RESULTS
The offspring of hypertensive parents had greater baseline systolic blood pressure (109 +/- 3 vs. 99 +/- 2 mm Hg, P=0.01), diastolic blood pressure (68 +/- 2 vs. 62 +/- 2 mm Hg, p=0.04), greater TC/HDL-C ratio (4.1 +/- 0.3 vs. 3.2 +/- 0.2, P<0.01), and greater LDL/HDL-C (2.7 +/- 0.2 vs. 1.9 +/- 0.1, P<0.01), and smaller values of HDL-C (43 +/- 2 vs.53 +/- 2 mg/dL, P<0.005). Dietary intake and anthropometric measures assessed did not differ between the groups. Even though dietary intervention resulted in reductions in body mass index (21.0+/- 1.2 vs. 20.1 +/- 1.1 kg/m(2), P<0.01), it did not change dyslipidemia present in the offspring of hypertensive individuals.


CONCLUSIONS
Increased blood pressure levels and less favorable lipid profiles are found among offspring of hypertensive parents, where low levels of HDL-C were the most relevant finding regardless of anthropometric or nutritional variables.
Elias
Maria Cristina
MC
Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.
Bolívar
Max Samuel Mattos
MS
Fonseca
Francisco Antonio Helfenstein
FA
Martinez
Tania Leme da Rocha
TL
Angelini
Japy
J
Ferreira
Celso
C
Kasinski
Nelson
N
de Paola
Angelo Amato Vincenzo
AA
Carvalho
Antonio Carlos Camargo
AC
D000293:Adolescent; D000367:Age Factors; D000886:Anthropometry; D001794:Blood Pressure / Q000502:physiology*; D002648:Child; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D006973:Hypertension / Q000235:genetics* / Q000378:metabolism / Q000503:physiopathology; D008055:Lipids / Q000097:blood*; D012307:Risk Factors
D008055:Lipids