Management of drug-induced hyperthermia.
OBJECTIVE
To review the current literature describing drug-induced hyperthermia and its treatment. Specifically, five syndromes will be discussed: malignant hyperthermia, neuroleptic malignant syndrome, anticholinergic poisoning, sympathomimetic poisoning, and serotonin syndrome.


RESULTS
The most recent findings in the literature are the recognition of previously undescribed drugs or drug combinations that have lead to hyperthermia. Recent literature also attests to the potential morbidity and mortality of drug-induced hyperthermia.


CONCLUSIONS
Although the recognition of causative agents is increasing, the treatment of drug-induced hyperthermia remains unchanged and continues to be primarily supportive.
Halloran
Lindara L
LL
Department of Pediatrics, University of Alabama School of Medicine, Birmingham, Alabama 35233, USA. lhalloran@peds.uab.edu
Bernard
David W
DW
D002648:Child; D018680:Cholinergic Antagonists / Q000506:poisoning; D005334:Fever / Q000139:chemically induced*; D006801:Humans; D008305:Malignant Hyperthermia / Q000209:etiology; D009459:Neuroleptic Malignant Syndrome / Q000209:etiology; D012701:Serotonin / Q000506:poisoning; D013566:Sympathomimetics / Q000506:poisoning
D018680:Cholinergic Antagonists; D013566:Sympathomimetics; D012701:Serotonin