title: [Integrated methods for assessing auditory nerve-auditory pathway integrity].
abstract: OBJECTIVE
  To evaluate the feasibility and value of integrated methods to assess auditory pathway integrity.
  
  
  METHODS
  Twenty-four cases of bilateral profoundly-deafened individuals who were considered as the candidates of cochlear implantation were included in this study. Auditory pathway integrity from these candidates of cochlear implantation were assessed with the integrated methods established by our team, which consist of 5 categories including 1. audiological test; 2. radiological imaging study; 3. ear-canal electric audiometry; 4. response to sound in daily life; and 5. speech development.
  
  
  RESULTS
  Twenty-three candidates who meet the criteria of auditory nerve-auditory pathway integrity received cochlear implantation with improved hearing and speech development postoperatively. The remainder one of the 24 candidates was diagnosed as bilateral absence of auditory nerve. The fault of cochlear implantation was avoided.
  
  
  CONCLUSIONS
  The integrated methods for assessing auditory pathway integrity is feasible and valuable. Auditory nerve-auditory pathway integrity should be considered and included as one of the most important criteria for cochlear implantation candidate.
authors.affiliation: Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022.
authors.forename: Weijia
authors.initials: W
authors.lastname: Kong
authors.forename: Jianxin
authors.initials: J
authors.lastname: Yue
authors.forename: Xin'gao
authors.initials: X
authors.lastname: Xiong
authors.forename: Lixin
authors.initials: L
authors.lastname: Zhu
authors.forename: Xiangquan
authors.initials: X
authors.lastname: Kong
authors.forename: Ping
authors.initials: P
authors.lastname: Han
authors.forename: Hui
authors.initials: H
authors.lastname: Ma
authors.forename: Jiade
authors.initials: J
authors.lastname: Duan
authors.forename: Chenkai
authors.initials: C
authors.lastname: Dai
authors.forename: Huamao
authors.initials: H
authors.lastname: Cheng
mesh_terms: D000161:Acoustic Stimulation; D000293:Adolescent; D001299:Audiometry / Q000379:methods; D001306:Auditory Pathways / Q000503:physiopathology*; D001309:Auditory Threshold; D002648:Child; D002675:Child, Preschool; D019929:Cochlear Implantation; D003056:Cochlear Nerve / Q000503:physiopathology*; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology; D005260:Female; D006312:Hearing Loss, Bilateral / Q000503:physiopathology; D006319:Hearing Loss, Sensorineural / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D007223:Infant; D008297:Male