[Immunological rapid urease test].
Immunological rapid urease test for detection of Helicobacter pylori infection, composed of a solid-phase tip coated with monoclonal antibody against H. pylori's urease and ion-sensitive field transistor (ISFT)-based pH sensor system, was developed. The monoclonal antibody against H. pylori's urease was useful to avoid the contamination of urease activity in other bacteria. Because ISFTT had high ability to detect pH change, the sensitivity and specificity of immunological rapid urease test was significantly improved comparing with that of conventional rapid urease test. The utility of immunological rapid urease test was evaluated in some clinical studies.
Kato
Mototsugu
M
Department of Endoscopy, Hokkaido University Hospital.
Nakagawa
Soichi
S
Shimizu
Yuichi
Y
Yuki
Satoshi
S
Fuse
Nozomu
N
Takei
Masaaki
M
Furukawa
Shigeru
S
Perez-Aldana
L A
LA
Rinan
Zheng
Z
Komatsu
Yoshito
Y
Saito
Nagahito
N
Takeda
Hiroshi
H
Sugiyama
Toshiro
T
Asaka
Masahiro
M
D000911:Antibodies, Monoclonal; D005750:Gastric Juice; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000201:enzymology*; D006801:Humans; D012680:Sensitivity and Specificity; D014510:Urease / Q000276:immunology*
D000911:Antibodies, Monoclonal; D014510:Urease