title: Neuronal nitric oxide synthase immunoreactivity in ependymal cells during early postnatal development.
abstract: Neuronal nitric oxide synthase (nNOS) immunoreactivity was observed in ependymal cell layer of the central canal of spinal cord of neonatal rats (2-20 days old). Neuronal nitric oxide synthase immunoreactivity was present in postnatal day 2 and this immunoreactivity gradually disappeared by postnatal day 16. The progressive decrease in nNOS staining with the increasing postnatal age may suggest that nNOS staining paralleled the maturation of the central canal and may also suggest that nNOS activity plays a role in the development of the ependymal cells.
authors.affiliation: Yüzüncü Yil Universitesi, Veteriner Fakültesi, Anatomi Anabilim Dali, Van, Turkey. zsoyguder@hotmail.com
authors.forename: Zafer
authors.initials: Z
authors.lastname: Soygüder
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Karadağ
authors.forename: Mümtaz
authors.initials: M
authors.lastname: Nazli
mesh_terms: D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D004805:Ependyma / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism*; D005260:Female; D008297:Male; D019001:Nitric Oxide Synthase / Q000378:metabolism*; D052248:Nitric Oxide Synthase Type I; D051381:Rats; D017208:Rats, Wistar; D013116:Spinal Cord / Q000378:metabolism
chemical_list: D019001:Nitric Oxide Synthase; D052248:Nitric Oxide Synthase Type I; C496322:Nos1 protein, rat