[The advantages of bovine jugular vein tanned with hydrophilia crosslinking agent].
The bovine jugular veins were divided into two groups and treated with 4% EX-313 and 0.5% glutaraldehyde respectively, and then they were examined with naked-eye, microscope and scanning electron microscope. Biomechnics test and dorsal implantation in rats were performed. The aquired data were processed and subjected to t-test. The EX-313 fixed material was more pliable than the glutaraldehyde treated material, and the former had higher anticalcification than the latter. In conclusion, the hydrophilia crosslinking agent EX-313 is superior to glutaraldehyde in treating biomaterials, and the bovine jugular vein tanned with EX-313 should be a promising material for repairing in cardiovascular surgery.
Chen
En
E
Shanghai Research Institute of Congenital Heart Disease for Children, Shanghai 200127, China.
Ding
Wenxiang
W
Lu
Yanan
Y
Jian
Zhuming
Z
Yu
Xiaoqing
X
Zhou
Wenyan
W
D000818:Animals; D001705:Bioprosthesis; D001807:Blood Vessel Prosthesis; D002417:Cattle; D003432:Cross-Linking Reagents / Q000494:pharmacology*; D005976:Glutaral / Q000494:pharmacology; D007601:Jugular Veins / Q000187:drug effects; D008422:Materials Testing; D051381:Rats; D017207:Rats, Sprague-Dawley; D023822:Tissue Engineering
D003432:Cross-Linking Reagents; D005976:Glutaral