[Diagnosis and treatment of juvenile recurrent laryngeal papillomatosis].
OBJECTIVE
To evaluate some perplexing problems in the diagnosis and treatment of juvenil recurrent laryngeal papillomatosis (JRLP) and the relationship between juvenile onset recurrent respiratory papillomatosis(JORRP) and infantile laryngeal condyloma accuminatum (ILCA).


METHODS
A group of 44 cases with JRLP were analyzed retrospectively from March, 1994 to March, 2002 in the light of literature review.


RESULTS
The average age of first visit was 1.6 years. Average 5.3 operations had been performed per patient. There was an interval of average 2.4 months between two surgical excisions. Of 233 operations, the total incidence rate of all the complications was 3.9%. At present, the laryngeal lesion of 18 cases have withered away for over 1 year. 11 cases have being followed up. 10 cases have lost follow-up and 5 cases have died (11.4%). Combined laryngeal lesion excision with tracheotomy aiming at prolonging operative interval or Chinese traditional medicine has received more satisfactory effect than other therapies. There is an extensive similarity between JORRP and ILCA.


CONCLUSIONS
To demondrate further whether JORRP and ILCA are the same identical disease has important significance in both theoretical study and clinic practice. The treatment for JRLP is still difficult. The tracheotomy for laryngeal obstruction resulted from the laryngeal lesion of JRLP should be avoided as far as possible. Combined laryngeal lesion excision with tracheotomy aiming at prolonging opertive interval or Chinese traditional medicine shows optimistic prospect.
Wang
Hui-ge
HG
Department of Otorhinolaryngology-Head and Neck Surgery, First Affiliated Hospital of Shantou University Medical College, Shantou 515041, China. hgwang@stu.edu.cn
Lin
Xin-qiang
XQ
D002648:Child; D002675:Child, Preschool; D003218:Condylomata Acuminata / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007370:Interferon Type I / Q000627:therapeutic use; D007818:Laryngeal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D008297:Male; D010212:Papilloma / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D008517:Phytotherapy; D012008:Recurrence; D012189:Retrospective Studies
D004365:Drugs, Chinese Herbal; D007370:Interferon Type I