Morphogenesis: shroom in to close the neural tube.
A novel actin-binding protein, Shroom, localises to precisely those cells that will constrict during cranial neural tube closure and appears pivotal in regulating the apical constrictions that drive epithelial foldings in vertebrate embryos.
Martin
Paul
P
Department of Physiology, School of Medical Sciences, University of Bristol, University Walk, UK. paul.martin@bristol.ac.uk
D000199:Actins / Q000378:metabolism; D000818:Animals; D002490:Central Nervous System / Q000196:embryology* / Q000378:metabolism; D004848:Epithelium / Q000196:embryology; D005786:Gene Expression Regulation; D051379:Mice / Q000196:embryology*; D008840:Microfilament Proteins / Q000235:genetics / Q000378:metabolism*; D009024:Morphogenesis / Q000235:genetics
D000199:Actins; D008840:Microfilament Proteins; C402112:Shrm protein, mouse