An outbreak of neurofilariosis in young goats.
An outbreak of cerebrospinal microfilariosis in 23 kids, representing a whole kid crop, occurred on a farm in Qassim, Central Saudi Arabia. The morbidity and mortality rates were 100%. Clinical signs, in kids from the fourth to sixth week of age, manifested as weakness in the hind legs followed by incoordination of movement and feet dragging. Seven to ten days later, the hind legs were completely paralyzed, and within a week the front legs were also paralyzed. The animals continued to feed, drink and suckle normally, and were in good health. Paralyzed kids were helped to suckle by the farm attendants. With time, loss of control of motor functions occurred and the ability to hold the head in upright position was lost, ability to eat or drink was lost. The infected kids health deteriorated and they eventually died. Two dead kids were postmortemed. With the exception of a meningeal haemorrhage seen in one kid, no obvious macroscopic lesions were seen in any of the autopsied animals. Histopathological examination of the spinal cord and brain showed different microfilaria of different sizes between the meninges and the nervous tissue. This indicated that development of the parasite occurred in the nervous tissue. The larger microfilaria contained black deposits, most likely to be digested blood, in their guts. It is likely that the parasites are haematophagus. The main lesions caused by the microfilaria were migratory traumatic haemorrhagic tracts in the spinal cord and the brain. These sometimes contained parts of the microfilariae. In the brain malacic lesions and sporadic aggregates of lymphocytes were also noted.
Mahmoud
O M
OM
Department of Veterinary Medicine, King Saud University, P.O. Box 1482, Buraydah, Qassim, Saudi Arabia. qagrvit@ksu.edu.sa
Haroun
E M
EM
Omer
O H
OH
D000818:Animals; D004196:Disease Outbreaks; D005368:Filariasis / Q000453:epidemiology / Q000469:parasitology / Q000662:veterinary*; D015511:Goat Diseases / Q000453:epidemiology / Q000469:parasitology*; D006041:Goats; D008842:Microfilariae / Q000254:growth & development*; D009422:Nervous System Diseases / Q000453:epidemiology / Q000469:parasitology / Q000662:veterinary*