title: [Rho-kinase inhibitor].
authors.affiliation: Department of Geriatric Medicine, Graduate School of Medical Sciences, Kyushu University.
authors.forename: Keizo
authors.initials: K
authors.lastname: Ohnaka
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Takayanagi
mesh_terms: D019307:1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D000577:Amides / Q000494:pharmacology / Q000627:therapeutic use; D015195:Drug Design; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D010012:Osteogenesis / Q000187:drug effects; D010024:Osteoporosis / Q000188:drug therapy / Q000209:etiology; D017346:Protein Serine-Threonine Kinases / Q000037:antagonists & inhibitors* / Q000502:physiology; D011725:Pyridines / Q000494:pharmacology / Q000627:therapeutic use; D054460:rho-Associated Kinases
chemical_list: D000577:Amides; D047908:Intracellular Signaling Peptides and Proteins; D011725:Pyridines; C431085:hydroxyfasudil; C108830:Y 27632; D019307:1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; D017346:Protein Serine-Threonine Kinases; D054460:rho-Associated Kinases; C049347:fasudil