Microwave-assisted amination from aryl triflates without base and catalyst.
[reaction: see text] Aryl triflates are effectively converted to the corresponding anilines under microwave irradiation in 1-methyl-2-pyridone (NMP) without base and catalyst. Aryl triflates substituted with both electron-poor and electron-rich groups give good to excellent yields. It is noteworthy that the halogenated aryl triflates can chemoselectively react with amines to afford halogenated anilines.
Xu
Gang
G
Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. China.
Wang
Yan-Guang
YG