title: The value of comparison.
abstract: With the number of published microbial genomes now in excess of 100, any new genome that is sequenced is likely to have a close relative available for comparison. Indeed, it is increasingly difficult to perform any genomic analysis that is not comparative. This should, however, not be seen as a drawback; it is often the case that a large amount of information can be drawn from these comparisons, especially between closely related organisms. Several genome sequences published recently indicate the value of comparisons at the genomic level.
authors.affiliation: Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
authors.forename: Nicholas
authors.initials: N
authors.lastname: Thomson
authors.forename: Mohammed
authors.initials: M
authors.lastname: Sebaihia
authors.forename: Ana
authors.initials: A
authors.lastname: Cerdeño-Tárraga
authors.forename: Stephen
authors.initials: S
authors.lastname: Bentley
authors.forename: Lisa
authors.initials: L
authors.lastname: Crossman
authors.forename: Julian
authors.initials: J
authors.lastname: Parkhill
mesh_terms: D001419:Bacteria / Q000235:genetics* / Q000472:pathogenicity; D018407:Bacterial Physiological Phenomena; D016123:Campylobacter jejuni / Q000235:genetics; D003352:Corynebacterium / Q000235:genetics; D016680:Genome, Bacterial; D044923:Helicobacter hepaticus / Q000235:genetics; D016480:Helicobacter pylori / Q000235:genetics; D009163:Mycobacterium bovis / Q000235:genetics; D009169:Mycobacterium tuberculosis / Q000235:genetics; D013297:Streptococcus pyogenes / Q000235:genetics; D014774:Virulence