[Effect of TCTS on experimental endometriosis of rats].
OBJECTIVE
To study the effect of TCTS on endometriosis rats.


METHODS
On the model of surgical induced rat endometriosis, weight and pathological changes of endometrial transplant and serum hormones were observed.


RESULTS
Weight of endometrial transplants was reduced by TCTS 11.2 g.kg-1 and 22.5 g.kg-1 and transplants of TCTS treated rat showed poorly developed epithelium, thinner stroma, fewer stromal cells and glands. At the same time elevated serum E2, FSH and LH were reduced by TCTS.


CONCLUSIONS
TCTS can inhibit the growth of endometrial transplants, which is related with serum hormone, especially E2.
Hong
Min
M
National Standard Lab of Pharmacology for Chinese Materia Medica, Nanjing 210029, Jiangsu, China.
Hua
Yong-qing
YQ
Yu
Li
L
Sun
Xiao-yu
XY
Li
Xiao-dong
XD
Zhu
Quan
Q
D000818:Animals; D002935:Cinnamomum zeylanicum / Q000737:chemistry; D030024:Curcuma / Q000737:chemistry; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D004715:Endometriosis / Q000097:blood / Q000473:pathology*; D004717:Endometrium / Q000473:pathology*; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D007986:Luteinizing Hormone / Q000097:blood; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D031347:Prunella / Q000737:chemistry; D051381:Rats; D017207:Rats, Sprague-Dawley; D014591:Uterine Diseases / Q000097:blood / Q000473:pathology*
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone