title: [Acquired lymphangiectasias or mammary dermolytic blisters with spontaneous resolution].
abstract: BACKGROUND
  Spontaneous occurrence of hemorrhagic blisters on the lower side of the breasts is an unusual clinical presentation of acquired lymphangiectasia.
  
  
  METHODS
  A 64 Year-old and a 85 Year-old woman had developed recurrent bleeding blisters in the sub-mammary region for several Months. Histological, immunohistochemical and electron microscopic examination revealed a subpapillary dermal bullous dehiscence, parallel to the epidermis, which was connected to lymphangiectasias of the superficial dermis. Their extreme dilatation and rupture were probably responsible for the clinical inflammatory and bleeding aspect of the lesions, which have not recurred after 1 and 3 Years, respectively.
  
  
  CONCLUSIONS
  The presence of subpapillary inflammatory lymphangiectasias might be responsible for recurrent dermal blister formation. The reason for the presence of these hemorrhagic lymphangiectasias, restricted to the sub-mammary location and their spontaneous regression after several flare-ups, remain unclear. The unusual clinical presentation of the lesions observed in these two women constitutes a differential diagnosis of acquired dermolytic blisters.
authors.affiliation: Service de Dermatologie, Centre Hospitalier Universitaire Saint-Pierre de Bruxelles, Belgique.
authors.forename: U
authors.initials: U
authors.lastname: Sass
authors.forename: J
authors.initials: J
authors.lastname: André
authors.forename: E
authors.initials: E
authors.lastname: Heid
authors.forename: E
authors.initials: E
authors.lastname: Grosshans
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001768:Blister / Q000150:complications* / Q000473:pathology; D001941:Breast Diseases / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008200:Lymphangiectasis / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D012075:Remission, Spontaneous