title: The potential danger of COX-2 inhibitors.
abstract: Cyclooxygenase (COX)-2 inhibitors have a major effect on ovulation and may impair fertilization, decidualization, implantation, and parturition, as well as female fertility. Women attempting to become pregnant need to pay more attention to their use of COX-2 inhibitors.
authors.affiliation: Department of Obstetrics and Gynecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia, Australia. robert.norman@adelaide.edu.au
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Norman
authors.forename: Ruijin
authors.initials: R
authors.lastname: Wu
mesh_terms: D000818:Animals; D051546:Cyclooxygenase 2; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors*; D008565:Membrane Proteins; D010060:Ovulation / Q000187:drug effects; D011448:Prostaglandin Antagonists / Q000009:adverse effects; D011451:Prostaglandin-Endoperoxide Synthases
chemical_list: D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D007527:Isoenzymes; D008565:Membrane Proteins; D011448:Prostaglandin Antagonists; D051546:Cyclooxygenase 2; C496540:PTGS2 protein, human; D011451:Prostaglandin-Endoperoxide Synthases