Swim posture of mice does not affect performance in the water maze.
We quantified swim postures of mice in relation to their cognitive performance. After training in a water maze, young (5-6 months) and aged (14-16 months) female apolipoprotein E-knockout (apoE0/0) mice and wild type controls were video taped while swimming. Subsequently, angles of body points with the water surface were calculated. Mice with a more horizontal swim posture (young and aged apoE0/0, aged wild type mice) also showed an increased body weight. However, swim posture was not related to cognitive performance.
Enthoven
L
L
Division of Medical Pharmacology, Leiden/Amsterdam Center for Drug Research and Leiden University Medical Center, Leiden University, PO Box 9502, 2300 RA Leiden, The Netherlands. l.enthoven@lacdr.leidenuniv.nl
Dalm
S
S
de Kloet
E R
ER
Oitzl
M S
MS
D000375:Aging / Q000502:physiology*; D000818:Animals; D001057:Apolipoproteins E / Q000172:deficiency / Q000235:genetics; D005260:Female; D018782:Maze Learning / Q000502:physiology*; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D011187:Posture / Q000502:physiology*; D013550:Swimming / Q000502:physiology*
D001057:Apolipoproteins E