Positron emission tomography imaging of the aging brain.
PET imaging provides a vital means to study the human brain in vivo in aging and early disease states. PET studies using selective markers for brain metabolism and neurotransmitter function have uncovered a wealth of information on healthy and pathologic brain aging, and its relationship to behavior and mood states. Recognition of inherent potential confounds in the use of PET in aging studies is essential to the proper interpretation of these data.
Meltzer
Carolyn Cidis
CC
Department of Radiology, University of Pittsburgh School of Medicine, CHP MT 3972, 200 Lothrop Street, Pittsburgh, PA 15213-2582, USA. meltzercc@msx.upmc.edu
Becker
James T
JT
Price
Julie C
JC
Moses-Kolko
Eydie
E
D000339:Affect; D000375:Aging / Q000378:metabolism; D001519:Behavior; D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000503:physiopathology; D001931:Brain Mapping; D002560:Cerebrovascular Circulation; D006801:Humans; D019636:Neurodegenerative Diseases / Q000000981:diagnostic imaging; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D017981:Receptors, Neurotransmitter / Q000378:metabolism*; D014055:Tomography, Emission-Computed
D019275:Radiopharmaceuticals; D017981:Receptors, Neurotransmitter