title: [Ivermectin use in tropical medicine].
abstract: Ivermectin is a major breakthrough for the treatment of onchocerciasis, strongyloidosis, scabies and cutaneous larva migrans. Combined with albendazole, ivermectin is highly efficient for treating lymphatic filariasis and intestinal worms. Ivermectin shows very few side-effects but its use in children below 5 and during pregnancy is discussed. Ivermectin tolerance could be related to mdr1 gene expression. Additional studies are needed to assess its efficiency for pediculosis.
authors.affiliation: Service de parasitologie-mycologie, CHU Cochin, AP-HP, 27, rue du Faubourg Saint-Jacques, 75014 Paris, France. jean.dupouy-camet@cch.ap-hop-paris.fr
authors.forename: J
authors.initials: J
authors.lastname: Dupouy-Camet
authors.forename: H
authors.initials: H
authors.lastname: Yera
authors.forename: C
authors.initials: C
authors.lastname: Tourte-Schaefer
mesh_terms: D000977:Antiparasitic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D006801:Humans; D007559:Ivermectin / Q000494:pharmacology / Q000627:therapeutic use*; D014330:Tropical Medicine
chemical_list: D000977:Antiparasitic Agents; D007559:Ivermectin