title: Effect of alkyl-beta,d-glucopyranosides on hypertonic haemolysis of erythrocytes.
abstract: The effect of temperature (5-20 degrees C) and treatment with phenylhydrazine on the hypertonic lysis of erythrocytes in the presence of alkyl-beta,d-glucopyranosides was studied. The results highlight an important role for the cytoskeleton-membrane complex, which allows the cells to both withstand hypertonic stress within the temperature range studied and facilitate the protective effect of alkylglucopyranosides at low temperatures (5 degrees C).
authors.affiliation: Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of the Ukraine, Kharkov, Ukraine. cryo@online.kharkov
authors.forename: Olga P
authors.initials: OP
authors.lastname: Synchykova
authors.forename: Natalia M
authors.initials: NM
authors.lastname: Shpakova
authors.forename: Valerij A
authors.initials: VA
authors.lastname: Bondarenko
mesh_terms: D003599:Cytoskeleton / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004912:Erythrocytes / Q000187:drug effects* / Q000502:physiology; D005947:Glucose / Q000494:pharmacology*; D006461:Hemolysis / Q000187:drug effects*; D006801:Humans; D006982:Hypertonic Solutions / Q000494:pharmacology; D009996:Osmotic Fragility / Q000187:drug effects; D010659:Phenylhydrazines / Q000494:pharmacology; D012965:Sodium Chloride; D013696:Temperature
chemical_list: D006982:Hypertonic Solutions; D010659:Phenylhydrazines; C030299:phenylhydrazine; D012965:Sodium Chloride; D005947:Glucose