Specification of chemosensory neuron subtype identities in Caenorhabditis elegans.
Cellular diversity in the nervous system arises from the presence of multiple neuronal subtypes, each of which is specialized to perform a unique function. Work in Caenorhabditis elegans has begun to reveal the pathways that are essential for the specification of identities of neuronal subtypes in its chemosensory system. The functions of each chemosensory neuron subtype are specified by distinct developmental cascades, using molecules from well-conserved transcription factor families. Additional cellular complexity is generated by novel mechanisms that further diversify the identities of the left and right members of a bilateral sensory neuron pair.
Lanjuin
Anne
A
Department of Biology, Brandeis University, MS008, 415 South Street, Waltham, MA 02454, USA.
Sengupta
Piali
P
D000818:Animals; D017173:Caenorhabditis elegans / Q000166:cytology* / Q000502:physiology; D029742:Caenorhabditis elegans Proteins / Q000502:physiology; D002628:Chemoreceptor Cells / Q000166:cytology* / Q000502:physiology; D006801:Humans; D009046:Motor Neurons / Q000166:cytology / Q000502:physiology; D009475:Neurons, Afferent / Q000166:cytology* / Q000502:physiology; D014157:Transcription Factors / Q000502:physiology
D029742:Caenorhabditis elegans Proteins; D014157:Transcription Factors