title: [Experimental study on effect of the water extract of dogwood fruits on the liver and testis in rats model of kidney-yang deficiency].
abstract: OBJECTIVE
  To explore the effect of Dogwood fruits on tonifying kidney-yang.
  
  
  METHODS
  The effect of the water extract of Dogwood fruits on rats model of kidney-yang deficiency with the hydrocortisone was observed.
  
  
  RESULTS
  The water extract of Dogwood fruits could make normal the liver weight, and mitigate hepatocyte pathologic changes, increase the heptocellular levels of RNA and hepatin, and decrease the malondialdehyde (MDA) in rats model of kidney-yang deficiency. It could also make the viscera quotiety return to normal way and increase the levels of RNA in the interstitial cells of testicle in rats model of kidney-yang deficiency.
  
  
  CONCLUSIONS
  Water extract of Dogwood fruits can protect and improve the functions of the liver and testicle in rats model of kidney-yang deficiency.
authors.affiliation: Xiyuan Hospital, China Academy of TCM, Beijing 100091, China.
authors.forename: Chun-sheng
authors.initials: CS
authors.lastname: Li
authors.forename: Guo-xi
authors.initials: GX
authors.lastname: Zhang
authors.forename: Ti-ren
authors.initials: TR
authors.lastname: Shi
authors.forename: Xiao-xia
authors.initials: XX
authors.lastname: Dong
authors.forename: Pi
authors.initials: P
authors.lastname: Sun
authors.forename: Dian-dong
authors.initials: DD
authors.lastname: Li
authors.forename: Hong-zhang
authors.initials: HZ
authors.lastname: Xu
authors.forename: Ke-ji
authors.initials: KJ
authors.lastname: Chen
mesh_terms: D000818:Animals; D029768:Cornus / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry; D006854:Hydrocortisone; D007674:Kidney Diseases / Q000139:chemically induced / Q000378:metabolism / Q000473:pathology*; D008099:Liver / Q000378:metabolism / Q000473:pathology*; D008112:Liver Glycogen / Q000378:metabolism; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D010946:Plants, Medicinal / Q000737:chemistry; D012313:RNA / Q000378:metabolism; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D013737:Testis / Q000378:metabolism / Q000473:pathology*; D016711:Yang Deficiency / Q000139:chemically induced / Q000378:metabolism / Q000473:pathology*
chemical_list: D004365:Drugs, Chinese Herbal; D008112:Liver Glycogen; D008315:Malondialdehyde; D012313:RNA; D006854:Hydrocortisone