title: Progressive supranuclear palsy: new disease or variant of postencephalitic parkinsonism?
abstract: We review the etiological importance of the epidemic encephalitis for progressive supranuclear palsy (PSP) and addresses the question of whether the explosion of PSP literature in the mid-20th century reflects the appearance of a new disease. We examined 2,000 studies on Parkinson's disease from 1861 to 1963 and found PSP-like cases in the past, before the epidemic encephalitis era. It can be assumed that PSP is neither a new disease nor a variant of postencephalitic parkinsonism.
authors.affiliation: Galliera Hospital, Genoa, Italy. adolfobrusa@virgilio.it
authors.forename: Adolfo
authors.initials: A
authors.lastname: Brusa
authors.forename: Rolf
authors.initials: R
authors.lastname: Stoehr
authors.forename: Peter P
authors.initials: PP
authors.lastname: Pramstaller
mesh_terms: D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D008297:Male; D008875:Middle Aged; D010301:Parkinson Disease, Postencephalitic / Q000175:diagnosis* / Q000266:history; D013494:Supranuclear Palsy, Progressive / Q000175:diagnosis* / Q000266:history