Synthesis of 2,2'-bipyrroles and 2,2'-thienylpyrroles from donor-acceptor cyclopropanes and 2-cyanoheteroles.
[reaction: see text] Two new series of 2,2'-bipyrroles and 2,2'-thienylpyrroles have been prepared by trimethylsilyl trifluoromethanesulfonate (TMSOTf)-mediated reaction of donor-acceptor cyclopropanes with 2-cyanopyrroles and 2-cyanothiophene, respectively. This method opens the door toward a wide variety of unsymmetrical bipyrroles and thienylpyrroles.
Yu
Ming
M
Department of Chemistry and Biochemistry, The University of Texas at Austin, Austin, Texas 78712, USA.
Pantos
G Dan
GD
Sessler
Jonathan L
JL
Pagenkopf
Brian L
BL
D003521:Cyclopropanes / Q000737:chemistry*; D015394:Molecular Structure; D011758:Pyrroles / Q000138:chemical synthesis*
D003521:Cyclopropanes; D011758:Pyrroles; C030797:cyclopropane