[Bacterial adherence in pathogenesis of urinary tract infectious].
The possibility of a colonization and later urinary infection is due to a first contact among a series of structures of the bacterium, denominated adhesins (fimbrica or no-fimbrica) and some receivers or ligands of the surface of the urinary epitelium. The bacterial fimbriae of Escherichia coli, of those that have been studied up to seven different types, are protean structures coded by the chromosomal DNA, being the most important those of type 1, in connection with the colonization of the low roads, and the type P, with the cystitis and pyelonephritis. They are studied with detail their different protean components and the very complex genetic regulation of their production, made of great interest in the pathogeny of these infections and in the possibility of their prevention. The receivers of each fimbriae type are also chemically different, and their knowledge would explain important clinical data.
Piédrola Angulo
Gonzalo
G
D018829:Adhesins, Bacterial / Q000235:genetics / Q000502:physiology; D001422:Bacterial Adhesion / Q000502:physiology; D010861:Fimbriae, Bacterial / Q000235:genetics / Q000502:physiology; D006801:Humans; D014552:Urinary Tract Infections / Q000382:microbiology*
D018829:Adhesins, Bacterial