[Analysis of the mutagenic activity examplified by interaction of DNA bases with nitrous acid].
Chromatography and spectrophotometry techniques were designed to evaluate both qualitatively and quantitatively a degree of DNA-base deamination provoked by nitric acid. A possibility is shown of how to apply the above method in studying the mutagene activity of deaminating agents.
Gaeva
E B
EB
Narezhnaia
E V
EV
Kornienko
I V
IV
D000225:Adenine / Q000737:chemistry; D002855:Chromatography, Thin Layer; D003596:Cytosine / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D019271:Hypoxanthine / Q000737:chemistry; D009152:Mutagenicity Tests / Q000379:methods*; D009608:Nitrous Acid / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D014498:Uracil / Q000737:chemistry
D019271:Hypoxanthine; D014498:Uracil; D003596:Cytosine; D004247:DNA; D000225:Adenine; D009608:Nitrous Acid