title: Using Caenorhabditis elegans to probe toxicity of 1-alkyl-3-methylimidazolium chloride based ionic liquids.
abstract: Ionic liquids are gaining attention as new solvents within the green chemistry community; however this attention has quickly outstripped current environmental and toxicological data available. In the present communication, we establish the use of Caenorhabditis elegans as a model organism for inexpensively and quickly exploring toxicological effects of 1-alkyl-3-methylimidazolium chloride ionic liquids.
authors.affiliation: Department of Chemistry and Center for Green Manufacturing, The University of Alabama, Tuscaloosa, 35487, USA.
authors.forename: Richard P
authors.initials: RP
authors.lastname: Swatloski
authors.forename: John D
authors.initials: JD
authors.lastname: Holbrey
authors.forename: Shermeen B
authors.initials: SB
authors.lastname: Memon
authors.forename: Guy A
authors.initials: GA
authors.lastname: Caldwell
authors.forename: Kim A
authors.initials: KA
authors.lastname: Caldwell
authors.forename: Robin D
authors.initials: RD
authors.lastname: Rogers
mesh_terms: D000818:Animals; D001681:Biological Assay / Q000379:methods*; D017173:Caenorhabditis elegans / Q000187:drug effects* / Q000502:physiology; D007093:Imidazoles / Q000633:toxicity*; D007477:Ions / Q000633:toxicity*; D009348:Nematoda / Q000187:drug effects / Q000502:physiology; D012997:Solvents / Q000633:toxicity*; D018675:Toxicity Tests / Q000379:methods*
chemical_list: D007093:Imidazoles; D007477:Ions; D012997:Solvents