title: [Hepatitis C in hemophiliacs].
abstract: Hepatitis C virus (HCV) infection is an important cause of morbidity and mortality in patients with hereditary bleeding disorders treated with non virus inactivated clotting factor concentrates during the 1970s. In this article, we briefly report the actual knowledge about HCV infection in hemophiliacs, by analyzing the prevalence of HCV infection, the genotype distribution, the natural history of the infection and the most important factors involved in the progression of chronic hepatitis into liver cirrhosis, hepatic decompensation and hepatocellular carcinoma. Finally, we describe the main advances in the treatment of HCV infection.
authors.forename: Massimo
authors.initials: M
authors.lastname: Franchini
authors.forename: Franco
authors.initials: F
authors.lastname: Capra
authors.forename: Dino
authors.initials: D
authors.lastname: Veneri
authors.forename: Giuliana
authors.initials: G
authors.lastname: Lo Cascio
authors.forename: Elena
authors.initials: E
authors.lastname: de Maria
authors.forename: Franco
authors.initials: F
authors.lastname: Manzato
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Lippi
authors.forename: Giorgio
authors.initials: G
authors.lastname: Gandini
mesh_terms: D006467:Hemophilia A / Q000150:complications*; D006526:Hepatitis C / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D012307:Risk Factors