Occult hepatitis B virus (HBV) infection in healthy blood donors.
Blood transfusion is an important route of transmission of hepatitis B virus (HBV). Occult HBV infection can exist in the absence of HBsAg and can be detected by determining HBV DNA. To determine the occult HBV infection in healthy blood donors. One hundred adult healthy blood donors, negative for HBsAg, anti HCV, HIV-1 and other risk factors were screened for HBV DNA by PCR. All the healthy blood donors were negative for HBV DNA by PCR. Occult HBV infection does not occur in the healthy blood donors in the population studied.
Duseja
Ajay
A
Department of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh. ajayduseja@hotmail.com
Sharma
Sanjeev
S
Subramanian
P G
PG
Agnihotri
S K
SK
Chakraborti
Anuradha
A
Chawla
Y
Y
D000328:Adult; D001782:Blood Donors; D004279:DNA, Viral / Q000097:blood / Q000235:genetics; D006509:Hepatitis B / Q000453:epidemiology* / Q000635:transmission; D006515:Hepatitis B virus / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D065227:Transfusion Reaction
D004279:DNA, Viral