title: Pure red cell aplasia--report of 11 cases from eastern Nepal.
abstract: There were eleven cases of pure red cell aplasia diagnosed over a period of 2 years (January 2000-December 2001). All the patients had anemia with pallor and weakness being the presenting complaints. Hematological profile depicted normocytic normochromic anemia, reticulocytopenia and marked paucity of erythroid precursors on bone marrow aspiration and biopsy studies. In the present study, one case was of congenital pure red cell aplasia, in one other case of pyrexia of unknown origin, no definitive diagnosis could be made. Other associated diseases seen with pure red cell aplasia were thymoma, septicemia, protein energy malnutrition, non-Hodgkin's lymphoma, juvenile rheumatoid arthritis, acute myeloid leukemia, tuberculosis and hepatitis C. The association of pure red cell aplasia with haematologic malignancies is rare. There are very few case reports on pure red cell aplasia with hepatitis C.
authors.affiliation: Department of Pathology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal. arvindak1969@yahoo.com
authors.forename: Arvind Kumar
authors.initials: AK
authors.lastname: Sinha
authors.forename: Anshoo
authors.initials: A
authors.lastname: Agarwal
authors.forename: Mamta
authors.initials: M
authors.lastname: Lakhey
authors.forename: Javed
authors.initials: J
authors.lastname: Ansari
authors.forename: Sudha
authors.initials: S
authors.lastname: Rani
mesh_terms: D000293:Adolescent; D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006526:Hepatitis C / Q000150:complications; D006801:Humans; D007231:Infant, Newborn; D008228:Lymphoma, Non-Hodgkin / Q000150:complications; D008297:Male; D008875:Middle Aged; D009390:Nepal; D012010:Red-Cell Aplasia, Pure / Q000150:complications / Q000151:congenital / Q000175:diagnosis*; D013945:Thymoma / Q000150:complications; D013953:Thymus Neoplasms / Q000473:pathology