[A revised classification of hypoxic conditions].
The precised classification of circulatory hypoxia described in the paper is principally different from those published earlier by that it discriminates between hypoxia preconditioned by impaired cardiac-muscle constriction, on the one hand, and hypoxia due to malfunctions of smooth muscles (SM), on the other hand. The genesis of SM malfunctions is predetermined by impaired interactions of serotonin with SM serotonin receptors. The clinical use of serotonin adipinat reduces the local organic and total-tissue hypoxia in different pathologies and provides for better treatment results. The mentioned precised classification can be used to gain more data on the tissue-hypoxia pathogenesis and to schedule the clinical-and-experimental research on the purpose-oriented basis.
Simonenkov
A P
AP
Fedorov
V D
VD
Kliuzhev
V M
VM
Ardashev
V N
VN
Vrublevskiĭ
O Iu
OIu
Karpun
N A
NA
Gorpinich
A B
AB
Chernov
M Iu
MIu
Korotchenko
S V
SV
D000272:Adipates / Q000494:pharmacology* / Q000627:therapeutic use; D000368:Aged; D000369:Aged, 80 and over; D015687:Cell Hypoxia / Q000187:drug effects / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009131:Muscle, Smooth, Vascular / Q000187:drug effects* / Q000503:physiopathology; D017202:Myocardial Ischemia / Q000145:classification* / Q000378:metabolism / Q000503:physiopathology*; D012701:Serotonin / Q000031:analogs & derivatives* / Q000494:pharmacology* / Q000627:therapeutic use
D000272:Adipates; C059902:serotonin adipinate; D012701:Serotonin