title: Morphometric ultrastructural analysis of satellite cells in denervated rat soleus muscle.
abstract: Morphometric analysis of the ultrastructural changes of satellite cells (SCs) of rat soleus muscle 7, 14, and 36 days post denervation was performed. Denervation caused decrease of surface area cross-section of SCs and their nuclei, volume fractions of nucleus and Golgi complex elements and ribosomes number. In contrast, the increase of surface area/volume ratio of SCs and nucleus, volume fraction and number of endosome/lysosome-like structures, and number of caveolae-like structures was noticed. Ultrastructural changes of SCs in denervated muscles strongly suggest decline of cell activity accompanied by increased processes of degradation of material of endo-, and/or egzogenous origin.
authors.affiliation: Department of Histology and Embryology, Center of Biostructure Research, 02-004 Warsaw, Poland. mkujawa@ib.amwaw.edu.pl
authors.forename: Marek
authors.initials: M
authors.lastname: Kujawa
authors.forename: Wojciech
authors.initials: W
authors.lastname: Baran
authors.forename: Ewa
authors.initials: E
authors.lastname: Jankowska-Steifer
mesh_terms: D000818:Animals; D005260:Female; D007091:Image Processing, Computer-Assisted; D008854:Microscopy, Electron; D009121:Muscle Denervation; D018482:Muscle, Skeletal / Q000166:cytology* / Q000294:innervation / Q000648:ultrastructure; D051381:Rats; D032496:Satellite Cells, Skeletal Muscle / Q000648:ultrastructure*