Effect of angiotensin-converting enzyme inhibitors, beta blockers, statins, and aspirin on C-reactive protein levels in outpatients with heart failure.
C-reactive protein (CRP) levels were measured in a cohort of 96 outpatients with heart failure. Baseline angiotensin-converting enzyme inhibitor plus beta-blocker use were associated with lower levels of CRP; no relation was found between CRP levels and aspirin or statin use.
Joynt
Karen E
KE
Department of Medicine/Division of Cardiology, Duke University Medical Center, Durham, North Carolina 27710, USA. oconn002@mc.duke.edu
Gattis
Wendy A
WA
Hasselblad
Vic
V
Fuzaylov
Sergey Y
SY
Serebruany
Victor L
VL
Gurbel
Paul A
PA
Gaulden
Laura H
LH
Felker
G Michael
GM
Whellan
David J
DJ
O'Connor
Christopher M
CM
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D000368:Aged; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D001241:Aspirin / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D002097:C-Reactive Protein / Q000187:drug effects*; D005260:Female; D006333:Heart Failure / Q000097:blood / Q000188:drug therapy* / Q000453:epidemiology / Q000401:mortality*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009657:North Carolina / Q000453:epidemiology; D010865:Pilot Projects; D011446:Prospective Studies
D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D002097:C-Reactive Protein; D001241:Aspirin