title: [Prevention of nephrolithiasis. Established strategies and new concepts].
abstract: During the last 2 decades in Germany, only minor efforts were expended for the prevention of urinary stones. Substantial technical progress simplified the treatment of existing calculi; thus, it was more convenient to treat a new stone than to prevent its recurrence. But times change! In these days of financial squeeze in the medical system, prevention becomes more attractive. Nevertheless, strategies for kidney stone prevention developed. Established concepts for dietary advice were rejected due to the results of new randomized studies. Moreover, new pharmacological substances were introduced for metaphyalxis. The new concepts are feasible for the daily routine. For some treatment modalities in stone prevention, there is valid evidence from the literature, which should encourage us to adopt these modalities in the future. A number of drugs are used as "good common practice" without any proof from a randomized trial. Often prospective and valid studies are not available. The present paper intends to describe the status quo of nephrolithiasis prevention in Germany, focussing on confirmed data and unsolved problems.
authors.affiliation: Abteilung Urologie und Kinderurologie, Arbeitsgruppe Harnsteine, Universitätsklinikum Ulm. michael.straub@medizin.uni-ulm.de
authors.forename: M
authors.initials: M
authors.lastname: Straub
authors.forename: R E
authors.initials: RE
authors.lastname: Hautmann
mesh_terms: D002216:Captopril / Q000627:therapeutic use; D002951:Citrates / Q000627:therapeutic use*; D019317:Evidence-Based Medicine / Q000379:methods* / Q000639:trends*; D005858:Germany; D006801:Humans; D007669:Kidney Calculi / Q000517:prevention & control*; D010346:Patient Care Management / Q000379:methods* / Q000639:trends*; D012076:Renal Agents / Q000627:therapeutic use*
chemical_list: D002951:Citrates; D012076:Renal Agents; D002216:Captopril