title: [Pharmacobezoar in a patient operated on for pyloric stenosis].
abstract: Bezoars are concretions made up of a variety of partially digested materials seen in several portions of the gastrointestinal tract; they may result in gastrointestinal obstruction. Bezoar types described in the scientific literature include bezoars resulting from drugs. Their development is usually associated with some predisposing risk factor. The case of a patient is described, who was admitted to the hospitaĺs Emergency Department because of a clinical event suggesting a gastrointestinal bleeding episode. After admission, endoscopy demonstrated the presence of a bezoar whose components included a great number of Adalat Oros tablets. A review of the drugs that induced bezoar formation is made, and associated risk factors, formation mechanisms, bezoar appearance, and treatments used are all described.
authors.affiliation: Servicio de Farmacia, Complejo Hospitalario de Jaén. marina20@supercable.es
authors.forename: J F
authors.initials: JF
authors.lastname: Marín Pozo
authors.forename: M
authors.initials: M
authors.lastname: Soriano Martínez
authors.forename: I
authors.initials: I
authors.lastname: Caba Porras
authors.forename: G
authors.initials: G
authors.lastname: Rodríguez Torné
authors.forename: A
authors.initials: A
authors.lastname: Castelo Luque
mesh_terms: D000368:Aged; D000863:Antacids / Q000009:adverse effects / Q000737:chemistry; D001630:Bezoars / Q000139:chemically induced*; D001803:Blood Transfusion; D002400:Cathartics / Q000009:adverse effects / Q000737:chemistry; D002482:Cellulose / Q000031:analogs & derivatives* / Q000737:chemistry; D003692:Delayed-Action Preparations / Q000009:adverse effects / Q000737:chemistry; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced*; D005773:Gastroscopy; D006801:Humans; D008297:Male; D009543:Nifedipine / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D011183:Postoperative Complications / Q000139:chemically induced*; D011707:Pyloric Stenosis / Q000601:surgery*; D012995:Solubility; D013270:Stomach; D013392:Sucralfate / Q000009:adverse effects / Q000737:chemistry; D013607:Tablets
chemical_list: D000863:Antacids; D002400:Cathartics; D003692:Delayed-Action Preparations; D013607:Tablets; C005062:acetylcellulose; D013392:Sucralfate; D002482:Cellulose; D009543:Nifedipine