Chorea and contraceptives: case report with pet study and review of the literature.
Chorea is a well-recognized but rare complication of oral contraceptive use. A 27-year-old woman developed right hemichorea while taking an oral contraceptive (OC). No other causes of chorea were found. A positron emission tomography (PET) study with (18)F-fluorodeoxyglucose demonstrated a dense focus of increased glucose metabolism involving the body of the left caudate nucleus. To our knowledge, this is the first report of a PET study in a patient with OC-induced chorea in the absence of systemic lupus erythematosus or antiphospholipid antibodies.
Vela
L
L
Department of Neurology, University of Miami, School of Medicine, Miami, Florida 33136, USA.
Sfakianakis
G N
GN
Heros
D
D
Koller
W
W
Singer
C
C
D000328:Adult; D002421:Caudate Nucleus / Q000378:metabolism; D002819:Chorea / Q000139:chemically induced*; D003276:Contraceptives, Oral / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D005947:Glucose / Q000378:metabolism; D006801:Humans; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D014055:Tomography, Emission-Computed
D003276:Contraceptives, Oral; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D005947:Glucose