Severity of ovarian hyperstimulation syndrome: its relation to number of conceptuses.
OBJECTIVE
To assess the possibility that number of days of hospital stay increases with an increasing number of conceptuses in patients with ovarian hyperstimulation syndrome (OHSS).


METHODS
We reviewed 100 OHSS patients who were treated with a conservative therapeutic approach; 15 patients conceived but experienced spontaneous abortion by 8 weeks' gestation (SA group), 24 patients conceived a single fetus (singleton group), 16 patients conceived 2 fetuses (n = 14) or 3 fetuses (n = 2) (multiple group), and 45 patients did not conceive (NC group). The number of days of hospital stay, number of days of albumin supplementation, and hospital days when patients exhibited a urine volume of > or = 1200 mL/day and a hematocrit of > 40% were compared among the four groups.


RESULTS
The number (SD) of days of hospital stay was 23.6 (9.0) days for the multiple group, 16.5 (7.7) days for the singleton group, 13.9 (7.6) days for the SA group, and 11.6 (4.8) days for the NC group. The orders of the other three variables were the same as that of the number of days of hospital stay, in that a larger number of days was observed with an increasing number of conceptuses.


CONCLUSIONS
Pregnant women sustained OHSS for a longer time with an increasing number of conceived fetuses.
Koike
Toshimitsu
T
Department of Obstetrics and Gynecology, Jichi Medical School, Minamikawachi-machi, Tochigi, Japan.
Minakami
Hisanori
H
Araki
Shigeo
S
Sayama
Masaaki
M
Matsubara
Shigeki
S
Suzuki
Mitsuaki
M
D000022:Abortion, Spontaneous / Q000139:chemically induced / Q000453:epidemiology; D000328:Adult; D000704:Analysis of Variance; D005260:Female; D005306:Fertilization; D006801:Humans; D007564:Japan / Q000453:epidemiology; D007902:Length of Stay / Q000706:statistics & numerical data*; D016471:Ovarian Hyperstimulation Syndrome / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology*; D010062:Ovulation Induction / Q000009:adverse effects* / Q000706:statistics & numerical data; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D013997:Time Factors