Complement function in mAb-mediated cancer immunotherapy.
Gelderman
Kyra A
KA
Department of Pathology L1-Q, Leiden University Medical Center, Postbox 9600, 2300 RC Leiden, The Netherlands.
Tomlinson
Stephen
S
Ross
Gordon D
GD
Gorter
Arko
A
D000276:Adjuvants, Immunologic / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology* / Q000627:therapeutic use; D000920:Antibody-Dependent Cell Cytotoxicity; D003167:Complement Activation / Q000187:drug effects; D003179:Complement C3b / Q000502:physiology; D015938:Complement Membrane Attack Complex / Q000502:physiology; D003165:Complement System Proteins / Q000502:physiology*; D003602:Cytotoxicity, Immunologic / Q000187:drug effects; D015195:Drug Design; D005936:Glucans / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D007167:Immunotherapy; D016177:Macrophage-1 Antigen / Q000276:immunology; D008565:Membrane Proteins / Q000037:antagonists & inhibitors / Q000502:physiology; D051379:Mice; D018448:Models, Immunological; D009363:Neoplasm Proteins / Q000037:antagonists & inhibitors / Q000502:physiology; D009369:Neoplasms / Q000276:immunology / Q000628:therapy*; D009374:Neoplasms, Experimental / Q000276:immunology / Q000628:therapy; D047071:beta-Glucans
D000276:Adjuvants, Immunologic; D000911:Antibodies, Monoclonal; D015938:Complement Membrane Attack Complex; D005936:Glucans; D016177:Macrophage-1 Antigen; D008565:Membrane Proteins; D009363:Neoplasm Proteins; D047071:beta-Glucans; D003179:Complement C3b; D003165:Complement System Proteins; C033363:beta-1,3-glucan