[99mTc-N-NOET myocardial perfusion imaging during exercise for diagnosis of coronary artery disease].
OBJECTIVE
To investigate the value of (99m)Tc-N-NOET(NOET) myocardial perfusion imaging during exercise in the diagnosis of coronary artery disease (CAD), and the relationship between exercise NOET lung/heart ratio and left ventricular diastolic function.


METHODS
Exercise-delayed NOET myocardial perfusion imaging was performed in 49 patients undergoing coronary angiography, among whom 29 had coronary stenosis>or=50% and 20 normal coronary artery.


RESULTS
The sensitivity and specificity of exercise NOET myocardial perfusion imaging were 86.2% and 95.0%, respectively, in the detection of CAD. The NOET lung/heart ratio of CAD patients with multiple branch involvement (0.76+/-0.13) was significantly higher than those of patients with single branch lesion (0.62+/-0.06) and with normal coronary artery (0.58+/-0.13, F=18.04, P=0.002- 0.001). When the lung/heart ratio was over 0.70, the sensitivity and specificity of the imaging for detecting the presence of multiple branch involvement were 93.5% and 83.3%, respectively. NOET lung/heart ratio showed a significant correlation with E/A ratio (r=-0.771, P<0.000 1).


CONCLUSIONS
Exercise NOET lung/heart ratios has diagnostic values for multiple branch lesions and left ventricular diastolic function abnormalities in patients with CAD.
Ouyang
Wei
W
Department of Nuclear Medicine, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China. oyw88@163.net
He
Guo-rong
GR
Liu
Jin-hua
JH
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D005080:Exercise Test; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D013859:Thiocarbamates
D015609:Organotechnetium Compounds; D013859:Thiocarbamates; C093922:technetium Tc 99m, bis(N-ethoxy-N-ethyldithiocarbamato)nitrido-