title: Relation between pulse pressure and survival in patients with decompensated heart failure.
abstract: Elevated pulse pressure (PP), an indicator of increased arterial stiffness, has been shown to predict adverse outcome in patients with stable heart failure. However, the dependence of PP on hemodynamic factors, such as stroke volume and peak aortic blood flow, suggests that the relation between PP and outcome may depend on the clinical setting. We evaluated the relation between PP and all-cause mortality in 489 patients with decompensated heart failure. We found that the association of PP with outcome in this setting is reversed, with low PP being an independent predictor of mortality.
authors.affiliation: Division of Cardiology, Rambam Medical Center, Haifa, Israel.
authors.forename: Doron
authors.initials: D
authors.lastname: Aronson
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Burger
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers; D001794:Blood Pressure; D018572:Disease-Free Survival; D005260:Female; D006333:Heart Failure / Q000401:mortality* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008404:Massachusetts / Q000453:epidemiology; D008875:Middle Aged; D011237:Predictive Value of Tests; D016016:Proportional Hazards Models; D016032:Randomized Controlled Trials as Topic; D016019:Survival Analysis
chemical_list: D015415:Biomarkers