Stromal invasion of the prostate following a complete response to bacillus Calmette-Guerin instillation therapy for carcinoma in situ of the ureter and the bladder.
Bacillus Calmette-Guerin (BCG) instillation therapy is now a standard therapy for high-risk superficial bladder cancer patients. Although the complete response rate is approximately 70%, extra-vesical progression is sometimes observed. In particular, those patients who present a positive urinary cytology even after complete response from bladder lesion should be thoroughly examined. We present two cases of stromal invasion of the prostate after complete remission by BCG therapy of carcinoma in situ of the ureter and bladder found by transrectal prostate biopsy.
Hara
Isao
I
Division of Urology, Kobe University Graduate School of Medicine, Kobe, Japan. hara@med.kobe-u.ac.jp
Yao
Akihisa
A
Muramaki
Mototsugu
M
Hikosaka
Satoko
S
Yamada
Yuji
Y
Kawabata
Gaku
G
Kamidono
Sadao
S
D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000368:Aged; D001500:BCG Vaccine / Q000627:therapeutic use; D002278:Carcinoma in Situ / Q000473:pathology* / Q000628:therapy; D015653:Cystectomy; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000556:secondary* / Q000601:surgery; D017154:Stromal Cells / Q000473:pathology*; D014516:Ureteral Neoplasms / Q000473:pathology* / Q000628:therapy; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000628:therapy
D000276:Adjuvants, Immunologic; D001500:BCG Vaccine