title: Hand-assisted laparoscopic colectomy vs open colectomy: a prospective randomized study.
abstract: BACKGROUND
  We compared the perioperative parameters and outcomes achieved with hand-assisted laparoscopic colectomy (HALC) vs open colectomy (OC) for the management of benign and malignant colorectal disease, including cancer patients treated with curative intent.
  
  
  METHODS
  Sixty eligible patients were randomized to either HALC (n = 30) or OC (n = 30) treatment groups. We used Pearson's chi-square and two-sample t-tests to compare the differences in demographics and perioperative parameters.
  
  
  RESULTS
  There were no significant differences in age, gender distribution, disease pattern, operative procedure, comorbidity, or history of abdominal surgery. The HALC patients had significantly shorter hospital stays and incision lengths, faster recovery of gastrointestinal function, less analgesic use and blood loss, and lower pain scores on postoperative days 1, 3, and 14. There were no significant differences in operative time, complications, or time to return to normal activity.
  
  
  CONCLUSIONS
  Hand-assisted laparoscopic colectomy (HALC) is safe and produces better therapeutic results in terms of perioperative parameters than OC.
authors.affiliation: Division of Colorectal Surgery, Tri-Service General Hospital, National Defense Medical Center, 325 Section 2, Cheng-Kong Road, Nei-Hu Dis 114, Taipei, Taiwan, ROC.
authors.forename: J-C
authors.initials: JC
authors.lastname: Kang
authors.forename: M-H
authors.initials: MH
authors.lastname: Chung
authors.forename: P-C
authors.initials: PC
authors.lastname: Chao
authors.forename: C-C
authors.initials: CC
authors.lastname: Yeh
authors.forename: C-W
authors.initials: CW
authors.lastname: Hsiao
authors.forename: T-Y
authors.initials: TY
authors.lastname: Lee
authors.forename: S-W
authors.initials: SW
authors.lastname: Jao
mesh_terms: D000328:Adult; D000368:Aged; D000700:Analgesics / Q000627:therapeutic use; D016063:Blood Loss, Surgical; D003082:Colectomy / Q000379:methods* / Q000706:statistics & numerical data; D003108:Colonic Diseases / Q000601:surgery*; D015179:Colorectal Neoplasms / Q000601:surgery*; D017558:Elective Surgical Procedures / Q000706:statistics & numerical data; D005260:Female; D006225:Hand; D006801:Humans; D010535:Laparoscopy / Q000379:methods* / Q000706:statistics & numerical data; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy / Q000453:epidemiology; D011446:Prospective Studies; D020127:Recovery of Function; D012002:Rectal Diseases / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D000700:Analgesics