title: [Effect of yirong oral liquid on the reperfusion injury in rats with cerebral infarction undergoing thrombolysis].
abstract: OBJECTIVE
  To observe the effect of Yirong Oral Liquid (YROL) on reperfusion injury in rats with cerebral infarction undergoing thrombolysis.
  
  
  METHODS
  Clinical reperfusion under thrombolysis was simulated by applying thrombolysis on reversible local cerebral ischemic rat model. In the rat model, effect of YROL on parameters concerning anti-oxidation capability, cerebral edema and ultrastructure of brain were observed.
  
  
  RESULTS
  YROL could alleviate the cerebral edema after reperfusion, markedly increase the activity of superoxide dismutase in blood plasma, decrease the content of malonyldialdehyde, inhibit the post-reperfusion lipid peroxidation, and significantly reduce the ischemia/reperfusion injury of nerve cells in brain of rat.
  
  
  CONCLUSIONS
  YROL has definite protecting effect on brain.
authors.affiliation: Beijing Hospital of the Integrated Traditional and Western Medicine, Beijing 100039.
authors.forename: Xue-gong
authors.initials: XG
authors.lastname: Feng
authors.forename: Mao-cai
authors.initials: MC
authors.lastname: Liu
authors.forename: Jing-bo
authors.initials: JB
authors.lastname: Sun
mesh_terms: D000818:Animals; D002544:Cerebral Infarction / Q000188:drug therapy* / Q000473:pathology; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D018696:Neuroprotective Agents / Q000627:therapeutic use; D008517:Phytotherapy; D051381:Rats; D017207:Rats, Sprague-Dawley; D015427:Reperfusion Injury / Q000517:prevention & control*; D013482:Superoxide Dismutase / Q000097:blood; D015912:Thrombolytic Therapy; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use
chemical_list: D004365:Drugs, Chinese Herbal; D018696:Neuroprotective Agents; D008315:Malondialdehyde; D013482:Superoxide Dismutase; D014568:Urokinase-Type Plasminogen Activator