[Studies on the new triterpenoid saponin of the aerial part of Cimicifuga foetida].
OBJECTIVE
To find new active constituents from the aerial part of Cimicifuga foetida.


METHODS
Various column chromatographic techniques were used for the isolation and purification of the principles. The structures were elucidated on the basis of spectral data and chemical evidences.


RESULTS
Four 9,19-cycloartane triterpenoid saponins were obtained and identified as Cimifoetiside III (25-anhydrocimigenol-3-O-beta-D-galactopyranoside, 1), 25-O-acetyl-cimigenol xylopyranoside (2), 25-O-acetyl-cimigenol galactopyranoside (3), 7 beta-hydrocimigenol xylopyranoside (4).


CONCLUSIONS
Compound 1 is new and compound 4 was isolated from this plant for the first time.
Pan
Rui-le
RL
Institute of Medicinal Plant, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100094, China.
Chen
Di-hua
DH
Si
Jian-yong
JY
Zhao
Xiao-hong
XH
Shen
Lian-gang
LG
D031885:Cimicifuga / Q000737:chemistry*; D005697:Galactosides / Q000737:chemistry / Q000302:isolation & purification*; D007810:Lanosterol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification
C487684:7 beta-hydrocimigenol xylopyranoside; D005697:Galactosides; D012503:Saponins; D014315:Triterpenes; C487683:cimifoetiside III; D007810:Lanosterol