Identification and analysis of phosphopeptides.
Reversible phosphorylation of serine, threonine and tyrosine residues in proteins is one of the key events in signal transduction. To understand the process of signal transduction on a molecular level, it is imperative to identify phosphorylation sites in proteins. In this review, we offer an overview of the different methods/technologies currently available to identify protein phosphorylation sites.
Chalmers
Michael J
MJ
Ion Cyclotron Resonance Program, National High Magnetic Field Laboratory, Tallahassee, FL 32310-3706, USA.
Kolch
Walter
W
Emmett
Mark R
MR
Marshall
Alan G
AG
Mischak
Harald
H
D005583:Fourier Analysis; D013058:Mass Spectrometry / Q000379:methods; D010748:Phosphopeptides / Q000032:analysis*
D010748:Phosphopeptides