title: T-cell rich B-cell lymphoma--a case report.
abstract: T-Cell-Rich B-Cell lymphoma (TCRBCL) is a recently described variant of diffuse large B-cell lymphoma characterized by a predominance of reactive T-cells and a minority of neoplastic large cells which may resemble the Reed-Sternberg cell or its variants. TCRBCL is a notorious mimicker of both lymphocyte predominance Hodgkin's disease (LPHD) and peripheral T-cell lymphoma (PTCL). Immunohistochemistry is mandatory for a definitive diagnosis. We report a case of TCRBCL which was mistaken for HD both on fine needle aspiration cytology and histopathology due to the presence of RS like cells. Immunohistochemistry resolved the diagnostic dilemma.
authors.affiliation: Department of Pathology, Kasturba Medical College, Mangalore, Karnataka. pairadharam@yahoo.co.in
authors.forename: Radha Ramachandra
authors.initials: RR
authors.lastname: Pai
authors.forename: Urmila Niranjan
authors.initials: UN
authors.lastname: Khadilkar
authors.forename: Muktha Ramesh
authors.initials: MR
authors.lastname: Pai
authors.forename: M
authors.initials: M
authors.lastname: Dinesh
mesh_terms: D000328:Adult; D015703:Antigens, CD / Q000378:metabolism; D003937:Diagnosis, Differential; D006689:Hodgkin Disease / Q000175:diagnosis; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology / Q000473:pathology*
chemical_list: D015703:Antigens, CD