Development of the zebrafish lateral line.
The lateral line system is simple (comprising six cell types), its sense organs form according to a defined and reproducible pattern, and its neurons are easily visualized. In the zebrafish, these advantages can be combined with a wealth of genetic tools, making this system ideally suited to a combined molecular, cellular and genetic analysis. Recent progress has taken advantage of these various qualities to elucidate the mechanism that drives the migration from head to tail of the sense organ precursor cells, and to approach the questions surrounding axonal guidance and target recognition.
Ghysen
Alain
A
Lab. Neurogenetics, INSERM E343, cc103 Université Montpellier II, Place E. Bataillon, 34095 Montpellier, France. aghysen@univ-montp2.fr
Dambly-Chaudière
Christine
C
D000818:Animals; D002465:Cell Movement / Q000502:physiology; D004627:Embryonic Induction / Q000502:physiology; D007839:Functional Laterality / Q000502:physiology*; D009420:Nervous System / Q000166:cytology / Q000196:embryology* / Q000254:growth & development; D012679:Sense Organs / Q000166:cytology / Q000196:embryology / Q000254:growth & development; D015027:Zebrafish / Q000196:embryology* / Q000254:growth & development