[Postoperative results of non-penetrating trabeculectomy for primary open-angle glaucoma].
OBJECTIVE
To estimate the postoperative results of non-penetrating trabeculectomy(NPT), the success rate of postoperative intraocular pressure(IOP) and the clinical factors affecting postoperative IOP were evaluated.


METHODS
32 eyes of 32 primary open-angle glaucoma(POAG) patients who underwent NPT as the first filtering surgery were enrolled in the study. We evaluated postoperative IOP using the Kaplan-Meier method, a proportional hazard model, and multiple logistic analysis.


RESULTS
53.2% of all patients had an IOP of less than 16 mmHg without antiglaucoma medication, and 63.8% had an IOP of less than 16 mmHg with antiglaucoma medication 36 months postoperatively. The performance of Nd:YAG trabeculopuncture(YLT) was indicated as a significant factor affecting postoperative IOP by the proportional hazard model(p = 0.037). 72.2% of patients who did not undergo YLT had an IOP of less than 16 mmHg without antiglaucoma medication, and 36.5% who underwent YLT had a postoperative IOP of less than 16 mmHg. There was significant difference between the both groups(log rank test, p = 0.045). Preoperative IOP with antiglaucoma medication was indicated as a significant factor affecting performance of YLT by multiple logistic analysis.


CONCLUSIONS
These results suggest that NPT may be useful to reduce the use of antiglaucoma medication in patients with POAG whose preoperative IOP is controllable with antiglaucoma medication.
Kawashima
Miwako
M
Department of Ophthalmology, Nihon University School of Medicine, 30-1 Oyaguchikami-machi, Itabashiku-ku, Tokyo 173-8610, Japan.
Yamazaki
Yoshio
Y
Mizuki
Kenji
K
Hayamizu
Fukuko
F
Nakagami
Takako
T
Tanaka
Chizuru
C
D000328:Adult; D005260:Female; D005902:Glaucoma, Open-Angle / Q000503:physiopathology* / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D011184:Postoperative Period; D011379:Prognosis; D016016:Proportional Hazards Models; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome
D016685:Mitomycin