[Surface modification of poly methyl methacrylate intraocular lens by alpha-allyl glucoside].
A method for improving the biocompatibility of the intraocular lens (IOL) and reducing the cell attachment was adopted in this study. The alpha-Allyl glucoside was used for the surface modification of the poly methyl methacrylate (PMMA) IOL by way of plasma-induced in situ polymerization. The surfaces of the control and treatment IOLs were characterized by contact angle estimation and ESCA techniques. The resolution, diopter and anti-fatigue of loops were determined by physical and optical methods. Cell attachment on the surfaces was examined by light microscopy. The results indicated that all of the treatment groups had excellent physical and optical properties. The modification with the use of alpha-Allyl glucoside could improve the hydrophilicity of the anterior surface of the PMMA IOLs and reduce the cell attachment.
Qu
Chao
C
Eye Center, Second Affiliated Hospital, Medical College of Zhejiang University, Hangzhou 310009, China.
Yao
Ke
K
Kou
Ruiqiang
R
Xu
Zhikang
Z
D000498:Allyl Compounds / Q000737:chemistry*; D001672:Biocompatible Materials; D005960:Glucosides / Q000737:chemistry*; D007910:Lenses, Intraocular; D008422:Materials Testing; D058105:Polymerization; D019904:Polymethyl Methacrylate / Q000737:chemistry*; D013499:Surface Properties
D000498:Allyl Compounds; D001672:Biocompatible Materials; D005960:Glucosides; D019904:Polymethyl Methacrylate