Susceptibility testing of Singapore strains of Mycoplasma hominis to tetracycline, gatifloxacin, moxifloxacin, ciprofloxacin, clindamycin, and azithromycin by the Etest method.
The minimal inhibitory concentrations of tetracycline, gatifloxacin, moxifloxacin, ciprofloxacin, clindamycin and azithromycin for 28 Singapore clinical Mycoplasma hominis strains were studied using the Etest method. Different incubation conditions did not affect susceptibility categories, except for tetracycline intermediate-susceptibility strains. Tetracycline-susceptibility was only 35.7%. All strains were susceptible to the fluoroquinolones and clindamycin but resistant to azithromycin.
Ngan
Cecilia C L
CC
Department of Pathology, Singapore General Hospital, Singapore 169608, Singapore. gptncl@sgh.com.sg
Lim
Tongying
T
Choo
Chin-Mun
CM
Toh
Grace L-X
GL
Lim
Yok-Seng
YS
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001372:Aza Compounds / Q000494:pharmacology; D017963:Azithromycin / Q000494:pharmacology; D002939:Ciprofloxacin / Q000494:pharmacology; D002981:Clindamycin / Q000494:pharmacology; D024901:Drug Resistance, Multiple, Bacterial; D024841:Fluoroquinolones / Q000494:pharmacology*; D000077734:Gatifloxacin; D006801:Humans; D008826:Microbial Sensitivity Tests; D000077266:Moxifloxacin; D019535:Mycoplasma hominis / Q000145:classification / Q000187:drug effects*; D011804:Quinolines / Q000494:pharmacology; D012494:Sampling Studies; D012680:Sensitivity and Specificity; D012846:Singapore; D013752:Tetracycline / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D001372:Aza Compounds; D024841:Fluoroquinolones; D011804:Quinolines; D002981:Clindamycin; D002939:Ciprofloxacin; D017963:Azithromycin; D013752:Tetracycline; D000077734:Gatifloxacin; D000077266:Moxifloxacin