title: C-reactive proteins as an indicator of sub-clinical infection in cases of premature rupture of membranes.
abstract: The present study was conducted on 25 cases of preterm, premature rupture of membranes and 25 patients preterm with intact membranes, between 28-36 weeks of gestation, admitted in the maternity ward of Obstetrics and Gynecology, PGIMS, Rohtak. The sensitivity and specificity of CRP determination was found to be 80% each as an early predictor of subclinical chorioamnionitis. TLC had a low sensitivity of 20% and specificity of 60% in detecting histopathological chorioamnionitis. So CRP estimation is a reliable marker for detection of early choriamnionitis, at the same time, it is quite affordable and reasonably simple.
authors.affiliation: Department of Microbiology, Postgraduate Institute of Medical Sciences, Rohtak, Haryana.
authors.forename: Santosh
authors.initials: S
authors.lastname: Saini
authors.forename: Nidhi
authors.initials: N
authors.lastname: Goel
authors.forename: Madhu
authors.initials: M
authors.lastname: Sharma
authors.forename: B
authors.initials: B
authors.lastname: Arora
authors.forename: Nidhi
authors.initials: N
authors.lastname: Garg
mesh_terms: D002097:C-Reactive Protein / Q000032:analysis*; D002821:Chorioamnionitis / Q000097:blood / Q000150:complications / Q000175:diagnosis; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000097:blood* / Q000150:complications*; D006801:Humans; D011237:Predictive Value of Tests; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood* / Q000175:diagnosis; D012680:Sensitivity and Specificity
chemical_list: D002097:C-Reactive Protein