title: Peliosis hepatis presenting as a multifocal hepatic pseudotumor: MR findings in two cases.
abstract: Two cases of pseudotumoral peliosis hepatis are presented with emphasis on MRI findings. One patient had four individual lesions, the other had two. Image characteristics in both were: heterogeneic signal intensity on T1-weighted images (T1WI) with areas of high-, intermediate, and low signal intensity; heterogeneic signal intensity on T2WI with presence of numerous intralesional "cystic" hyperintense areas with a hypointense border. Signal intensities on T1WI were iso- to hypointense in one case and mild central hyperintensities were demonstrated in the other case, probably due to intra-lesional hemorrhage or diffuse accumulation of fresh clotting within the sinusoids. One case demonstrated early enhancement of the peripheral borders in the arterial phase, and both demonstrated enhancement in the portovenous and late phases. One case was studied with Gd-BOPTA and iron oxides and demonstrated enhancement with both products, suggestive for the presence of hepatocytes and Kupffer cells. This is the first report of the use of hepato-specific contrast agents in this entity. Spontaneous regression of the lesions was demonstrated on a follow-up MR examination in one case.
authors.affiliation: Department of Radiology, Ziekenhuis Oost Limburg, Campus St. Jan, Schiepse Bos 6, 3600 Genk, Belgium. geert_verswijvel@hotmail.com
authors.forename: G
authors.initials: G
authors.lastname: Verswijvel
authors.forename: F
authors.initials: F
authors.lastname: Janssens
authors.forename: P
authors.initials: P
authors.lastname: Colla
authors.forename: S
authors.initials: S
authors.lastname: Mampaey
authors.forename: H
authors.initials: H
authors.lastname: Verhelst
authors.forename: P
authors.initials: P
authors.lastname: Van Eycken
authors.forename: W
authors.initials: W
authors.lastname: Erven
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D019786:Gadolinium DTPA; D006104:Granuloma, Plasma Cell / Q000175:diagnosis*; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D010382:Peliosis Hepatis / Q000175:diagnosis*; D018570:Risk Assessment; D012680:Sensitivity and Specificity
chemical_list: D019786:Gadolinium DTPA