title: No-D NMR (no-deuterium proton NMR) spectroscopy: a simple yet powerful method for analyzing reaction and reagent solutions.
abstract: [reaction: see text] The title technique is a convenient and powerful method for directly monitoring or assaying any reaction mixture or reagent solution. Examples of some common processes (Fischer esterification, lithiation, butyllithium/THF compatibility, olefin metathesis, and a quantification assay), each interrogated in its native solvent, are presented. The spectral data are easy to acquire, and the information content makes a compelling case for routine use of No-D NMR spectroscopy.
authors.affiliation: Department of Chemistry, University of Minnesota, 207 Pleasant St., SE, Minneapolis, Minnesota 55455, USA. hoye@chem.umn.edu
authors.forename: Thomas R
authors.initials: TR
authors.lastname: Hoye
authors.forename: Brian M
authors.initials: BM
authors.lastname: Eklov
authors.forename: Troy D
authors.initials: TD
authors.lastname: Ryba
authors.forename: Mikhail
authors.initials: M
authors.lastname: Voloshin
authors.forename: Letitia J
authors.initials: LJ
authors.lastname: Yao
mesh_terms: D003903:Deuterium; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D011522:Protons; D012996:Solutions
chemical_list: D007202:Indicators and Reagents; D011522:Protons; D012996:Solutions; D003903:Deuterium