title: Body composition characteristics and fat distribution patterns in young infertile women.
abstract: OBJECTIVE
  To document body composition and fat patterning characteristics in normal and underweight infertile women.
  
  
  METHODS
  Status quo method.
  
  
  METHODS
  University clinics.
  
  
  METHODS
  Fifteen amenorrheic women with anorexia nervosa, 16 women with polycystic ovary syndrome (PCO2), 10 women with primary amenorrhea and 19 healthy controls.
  
  
  METHODS
  None.
  
  
  METHODS
  Determination of body mass index, body composition parameters such as fat mass, lean body mass, bone mass using dual-energy x-ray absorptiometry (DEXA), fat distribution patterns, 17beta-estradiol, FSH, LH, prolactin, progesterone, testosterone, DHEA-S, and androstenedione levels.
  
  
  RESULTS
  A statistically significant difference was found comparing all proband groups with healthy controls for the majority of body fat and bone mineral content parameters but not for lean body mass. Infertile women of normal weight, with PCOS, and with primary amenorrhea exhibited an extraordinarily high amount of fat tissue and a tendency toward android fat patterning. In contrast, patients with anorexia nervosa and the healthy controls showed predominantly gynoid fat patterning. According to logistic regression analyses, anorexia nervosa was characterized by reduced fat tissue and PCOS was characterized by android fat patterning and an increased fat percentage. Patients with primary amenorrhea were characterized by reduced bone mass.
  
  
  CONCLUSIONS
  Infertile young women showed characteristic differences in body composition and fat distribution patterns when compared with healthy, fertile, age-matched counterparts.
authors.affiliation: University for Clinic Gynecology and Obstetrics, Department of Endocrinology, University of Vienna Medical School, Vienna, Austria. sylvia.kirchengast@univie.ac.at
authors.forename: Sylvia
authors.initials: S
authors.lastname: Kirchengast
authors.forename: Johannes
authors.initials: J
authors.lastname: Huber
mesh_terms: D000273:Adipose Tissue / Q000473:pathology*; D000328:Adult; D000568:Amenorrhea / Q000150:complications / Q000378:metabolism / Q000473:pathology; D000856:Anorexia Nervosa / Q000150:complications / Q000378:metabolism / Q000473:pathology; D001823:Body Composition; D019521:Body Patterning; D015519:Bone Density; D016022:Case-Control Studies; D005260:Female; D006728:Hormones / Q000097:blood; D006801:Humans; D007247:Infertility, Female / Q000378:metabolism / Q000473:pathology*; D016015:Logistic Models; D011085:Polycystic Ovary Syndrome / Q000378:metabolism / Q000473:pathology
chemical_list: D006728:Hormones