Insertional oncogenesis in gene therapy: how much of a risk?
Sadelain
M
M
1Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
D000818:Animals; D002986:Clinical Trials as Topic; D005786:Gene Expression Regulation; D015316:Genetic Therapy / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000209:etiology; D051379:Mice; D023421:Models, Animal; D016254:Mutagenesis, Insertional; D009857:Oncogenes; D018570:Risk Assessment; D016511:Severe Combined Immunodeficiency / Q000628:therapy