Pathogenic Escherichia coli.
Few microorganisms are as versatile as Escherichia coli. An important member of the normal intestinal microflora of humans and other mammals, E. coli has also been widely exploited as a cloning host in recombinant DNA technology. But E. coli is more than just a laboratory workhorse or harmless intestinal inhabitant; it can also be a highly versatile, and frequently deadly, pathogen. Several different E. coli strains cause diverse intestinal and extraintestinal diseases by means of virulence factors that affect a wide range of cellular processes.
Kaper
James B
JB
Center for Vaccine Development, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. jkaper@umaryland.edu
Nataro
James P
JP
Mobley
Harry L
HL
D000818:Animals; D001422:Bacterial Adhesion; D003967:Diarrhea / Q000209:etiology; D004926:Escherichia coli / Q000235:genetics / Q000472:pathogenicity*; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D016920:Meningitis, Bacterial / Q000209:etiology; D022603:Shiga Toxins / Q000633:toxicity; D014552:Urinary Tract Infections / Q000209:etiology; D037521:Virulence Factors
D022603:Shiga Toxins; D037521:Virulence Factors