title: [Localization of NADPH diaphorase in central nervous system of the chiton Leptochiton assimilis in normal conditions and during hypoxia].
abstract: By light and electron microscope histochemical and cytochemical methods, the localization and activity of NADPH-diaphorase (NADPH-d) were studied in the central nervous system (CNS) of the chiton in control and after hypoxia. After acute hypoxia, the enzymatic activity increased in all regions of CNS. At a chronic hypoxia, the activity of NADPH-d decreased to remain, however, higher than in control. Ultrastructural studies confirmed the availability of structural changes in neurons, and shifts in the activity of NADPH-d in control and in experimental mollusks. The elevated enzymatic activity revealed in this study may be due to the fact that these mollusks have been evolutionary adapted to a periodical oxygen deficiency.
authors.affiliation: Institute of Marine Biology, Far East Department of the RAS, Vladivostok. inmarbio@mail.primorye.ru
authors.forename: E P
authors.initials: EP
authors.lastname: Kotsiuba
mesh_terms: D000693:Anaerobiosis; D000818:Animals; D002490:Central Nervous System / Q000201:enzymology / Q000648:ultrastructure; D006651:Histocytochemistry; D008974:Mollusca / Q000201:enzymology* / Q000648:ultrastructure; D009252:NADPH Dehydrogenase / Q000032:analysis / Q000378:metabolism*; D015854:Up-Regulation
chemical_list: D009252:NADPH Dehydrogenase