[Isolation and elucidation of chemical constituents with antiviral action from yinqiaosan on influenza virus].
OBJECTIVE
To study the chemical constituents with antiviral action from Yinqiaosan on influenza virus.


METHODS
Constituents were isolated by different kinds of column chromatography and their structures were elucidated with chemical and spectral methods.


RESULTS
Eleven chemical constituents were isolated and elucidated as arctiin, phillyrin, forsythiaside, liquiritigenin, liquiritin, genistein, formononetin, daidzein, glycitrin, 3,3',4-tri-omethlellagic acid and chlorogenic acid.


CONCLUSIONS
Genistein, daidzein, glycitrin and 3,3',4-tri-omethlellagic acid were isolated from Yinqiaosan for the first time.
Shi
Yue
Y
School of Life Sciences and Engineering, Tsinghua University, Beijing 100084, China. shiyue1029@hotmail.com
Shi
Ren-bing
RB
Liu
Bin
B
Lu
Yun-ru
YR
Du
Li-jun
LJ
D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification*; D031170:Arctium / Q000737:chemistry; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D031657:Forsythia / Q000737:chemistry; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification; D019833:Genistein / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification; D007529:Isoflavones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*
D000998:Antiviral Agents; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D005663:Furans; D005960:Glucosides; D006027:Glycosides; D007529:Isoflavones; C004742:daidzein; D019833:Genistein; C058049:forsythiaside; C077992:arctiin; C075528:phillyrin