Histoplasmosis presenting as addisonian crisis in an immunocompetent host.
A 71-year-old man with presumptively treated pulmonary tuberculosis ten years earlier and previous alcoholism presented with adrenal insufficiency. HIV serology was negative. A computerized tomography scan of the abdomen showed enlarged right adrenal. He recovered after emergency treatment with hydrocortisone IV. Right adrenalectomy was performed. Histoplasmosis was diagnosed and the patient was treated with itraconazole, corticosteroid replacement, and discharged with good health.
Chedid
Marcio Fernandes
MF
Serviço de Transplante Hepático Adulto, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
Chedid
Aljamir Duarte
AD
Geyer
Geraldo Resin
GR
Chedid
Maria Bernadete Fernandes
MB
Severo
Luiz Carlos
LC
D000224:Addison Disease / Q000188:drug therapy / Q000382:microbiology*; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D002908:Chronic Disease; D006658:Histoplasma / Q000302:isolation & purification; D006660:Histoplasmosis / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D016867:Immunocompromised Host; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male
D000935:Antifungal Agents; D017964:Itraconazole; D006854:Hydrocortisone