title: Monitoring the antioxidant activity of extracts originated from various Serratula species and isolation of flavonoids from Serratula coronata.
abstract: The antioxidant effect of aqueous methanolic herb extracts of Serratula coronata, S. wolffii and S. tinctoria was investigated using both enzyme-dependent and enzyme-independent systems. The extracts displayed concentration-dependent inhibition of lipid peroxidation. Flavonoids and ecdysteroids present in the extracts were evaluated as antioxidant components. The flavonoid-containing fraction of the herb extract of S. coronata was more effective in lipid peroxidation than the ecdysteroid-containing fraction. This paper also reports the isolation of quercetin 3-O-methyl ether, apigenin, luteolin, quercetin, luteolin 4'beta-D-glucoside and quercetin 4'beta-D-glucoside from S. coronata.
authors.affiliation: Department of Pharmacognosy, University of Szeged, Eötvös u. 6, Szeged 6720, Hungary. bathori@pharma.szote.u-szeged.hu
authors.forename: Mária
authors.initials: M
authors.lastname: Báthori
authors.forename: István
authors.initials: I
authors.lastname: Zupkó
authors.forename: Attila
authors.initials: A
authors.lastname: Hunyadi
authors.forename: Eszter
authors.initials: E
authors.lastname: Gácsné-Baitz
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Dinya
authors.forename: Péter
authors.initials: P
authors.lastname: Forgó
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D029748:Caryophyllaceae; D004305:Dose-Response Relationship, Drug; D005419:Flavonoids / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D015227:Lipid Peroxidation / Q000187:drug effects*; D008862:Microsomes, Liver / Q000187:drug effects; D008517:Phytotherapy; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D010936:Plant Extracts