title: Stainless and shape memory alloy coronary stents: a computational study on the interaction with the vascular wall.
abstract: Balloon-expandable and self-expandable stents are the two types of coronary stents available. Basically, they differ in the modality of expansion. The present study analyses the stress state induced on the vascular wall, by the expansion of balloon- and self-expandable stents, using the finite element method. Indeed, modified mechanical stress state is in part responsible in the restenosis process. The balloon-expandable stents herein investigated are assumed to be made of stainless steel, while the self-expandable stents are made of a shape memory alloy. The effects of the severity of the coronary stenosis, the atherosclerotic plaque stiffness and the stent design are investigated. Comparing the self-expandable stent with the balloon-expandable one, the former induces fewer stresses and lower damage to the vessel, but, on the other hand, its lower stiffness induces a lower capability to restore vasal lumen and to contrast arterial elastic recoil.
authors.affiliation: Dipartimento di Bioingegneria, Politecnico di Milano, Milan, Italy. francesco.migliavacca@polimi.it
authors.forename: Francesco
authors.initials: F
authors.lastname: Migliavacca
authors.forename: Lorenza
authors.initials: L
authors.lastname: Petrini
authors.forename: Paolo
authors.initials: P
authors.lastname: Massarotti
authors.forename: Silvia
authors.initials: S
authors.lastname: Schievano
authors.forename: Ferdinando
authors.initials: F
authors.lastname: Auricchio
authors.forename: Gabriele
authors.initials: G
authors.lastname: Dubini
mesh_terms: D000497:Alloys; D001158:Arteries / Q000503:physiopathology / Q000601:surgery; D001807:Blood Vessel Prosthesis; D003198:Computer Simulation; D017076:Computer-Aided Design; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery*; D003331:Coronary Vessels / Q000503:physiopathology / Q000601:surgery; D003936:Diagnosis, Computer-Assisted / Q000379:methods; D004548:Elasticity; D019544:Equipment Failure Analysis / Q000379:methods*; D006801:Humans; D008422:Materials Testing; D008955:Models, Cardiovascular; D011474:Prosthesis Design / Q000379:methods; D013193:Stainless Steel; D015607:Stents; D013314:Stress, Mechanical; D025321:Surgery, Computer-Assisted / Q000379:methods
chemical_list: D000497:Alloys; D013193:Stainless Steel