Granulocytic sarcoma of the testis.
Granulocytic sarcoma is a rare tumor composed of neoplastic blood cells, typically occurring during the course of, or before the onset of, acute nonlymphoblastic leukemia. We present a case of a 37-year-old man with acute testicular pain who was found to have a testicular mass diagnosed as granulocytic sarcoma (GS). Because GS virtually always progresses to leukemia, he underwent postoperative radiotherapy and chemotherapy. He was free of disease 6 months after treatment. This case highlights a rare hematologic cancer that urologists and pathologists should be aware of because it can present as a testicular mass.
Eggener
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Department of Urology, Northwestern University School of Medicine, Chicago, Illinois 60611, USA.
Abrahams
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Keeler
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D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D002466:Cell Nucleolus / Q000648:ultrastructure; D017024:Chemotherapy, Adjuvant; D002843:Chromatin / Q000648:ultrastructure; D003131:Combined Modality Therapy; D003561:Cytarabine / Q000008:administration & dosage; D003630:Daunorubicin / Q000008:administration & dosage; D018450:Disease Progression; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000517:prevention & control; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D009919:Orchiectomy; D018714:Radiotherapy, Adjuvant; D023981:Sarcoma, Myeloid / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery
D014408:Biomarkers, Tumor; D002843:Chromatin; D003561:Cytarabine; D008727:Methotrexate; D003630:Daunorubicin