title: Combined occurrence of von Willebrand's disease and factor XIII deficiency: a case report.
abstract: We report the case of a three year old female child with combined occurrence of von Willebrand's disease and factor XIII deficiency, an extremely rare combination. The patient presented with prolonged bleeding following cuts and wounds. Clot solubility test using 5M urea was positive. Platelet aggregation using ristocetin was reduced, which corrected on adding normal plasma. Aggregation with other agonists was normal. We discuss the clinico- hematological profile of the case. Only one such case has been reported in literature in the past to the best of our knowledge.
authors.affiliation: Department of Hematology, All India Institute of Medical Sciences, New Delhi. vvbatraa@2rediffmail.com
authors.forename: Vineeta Vijay
authors.initials: VV
authors.lastname: Batra
authors.forename: Renu
authors.initials: R
authors.lastname: Saxena
authors.forename: Lalit Mohan
authors.initials: LM
authors.lastname: Sharma
authors.forename: Rajesh
authors.initials: R
authors.lastname: Kashyap
authors.forename: Ved Prakash
authors.initials: VP
authors.lastname: Chaudhry
mesh_terms: D002675:Child, Preschool; D005177:Factor XIII Deficiency / Q000097:blood / Q000150:complications*; D005260:Female; D006801:Humans; D010641:Phenotype; D014842:von Willebrand Diseases / Q000097:blood / Q000150:complications*