title: Uncertainties in radiation therapy: target definition in carcinoma of the uterine cervix.
abstract: In treatment of patients with carcinoma of the cervix, as in any other malignant tumor, accurate identification of target volumes is critical to enhance precision of radiation therapy planning and delivery. These results in improved locoregional tumor control lead to lower incidence of distant metastases and improved survival. Also, radiation therapy morbidity is decreased, enhancing quality of life. Various imaging techniques are available to achieve better target delineation and this can be enhanced with image fusion. Available innovative treatment techniques to optimize the use of radiation therapy for these patients are illustrated.
authors.affiliation: Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO 63108, USA.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Perez
authors.forename: Perry W
authors.initials: PW
authors.lastname: Grigsby
authors.forename: Inram
authors.initials: I
authors.lastname: Zoberi
mesh_terms: D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D010388:Pelvis; D011785:Quality Assurance, Health Care; D011880:Radiotherapy Planning, Computer-Assisted / Q000592:standards; D020266:Radiotherapy, Conformal / Q000592:standards; D014055:Tomography, Emission-Computed; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy*