title: Clinically significant autoantibodies--a case report.
abstract: Auto antiA1 and anti H was found in the serum of a patient admitted in this hospital for intracardiac repair of Ventricular Septal defect (VSD). Blood was grouped as A1 positive with discrepant cell and serum grouping due to auto anti A1 and anti H. No blood units were compatible for the patient. 17 A1, 3 A2 and 8 O group blood units were crossmatched and found incompatible at 37 degrees C and A2 and O at 25 degrees C--as the patient required surgery at hypothermia. Surgery was postponed. Antibody status was reviewed after 4 months. The thermal amplitude of auto anti H had changed by then but there was no change in auto anti A1. Surgery was done using A2 group blood.
authors.affiliation: Division of Blood Transfusion Services, Sree Chitra Tirunal Instt for Medical Sciences and Technology, Thiruvananthapuram, Kerala.
authors.forename: P V
authors.initials: PV
authors.lastname: Sulochana
authors.forename: S
authors.initials: S
authors.lastname: Sathyabhama
authors.forename: Jaisy
authors.initials: J
authors.lastname: Mathai
authors.forename: K S Sheela
authors.initials: KS
authors.lastname: Devi
mesh_terms: D000017:ABO Blood-Group System / Q000276:immunology*; D000293:Adolescent; D001323:Autoantibodies / Q000097:blood*; D001788:Blood Grouping and Crossmatching; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000276:immunology / Q000601:surgery; D006801:Humans; D013696:Temperature
chemical_list: D000017:ABO Blood-Group System; D001323:Autoantibodies