title: Melanocins A, B and C, new melanin synthesis inhibitors produced by Eupenicillium shearii. II. Physico-chemical properties and structure elucidation.
abstract: New melanin synthesis inhibitors, melanocins A, B and C, were isolated from the fermentation broth and extract of mycelium of Eupenicillium shearii F80695. The structures of melanocins were established by spectroscopic methods. They are formamide compounds. In particular, melanocin A has an isocyanide group.
authors.affiliation: Korea Research Institute of Bioscience and Biotechnology, Yuseong, Daejeon 305-600, Korea.
authors.forename: Jong-Pyung
authors.initials: JP
authors.lastname: Kim
authors.forename: Byoung-Kwon
authors.initials: BK
authors.lastname: Kim
authors.forename: Bong-Sik
authors.initials: BS
authors.lastname: Yun
authors.forename: In-Ja
authors.initials: IJ
authors.lastname: Ryoo
authors.forename: In-Kyoung
authors.initials: IK
authors.lastname: Lee
authors.forename: Won-Gon
authors.initials: WG
authors.lastname: Kim
authors.forename: Yu-Ryang
authors.initials: YR
authors.lastname: Pyun
authors.forename: Ick-Dong
authors.initials: ID
authors.lastname: Yoo
mesh_terms: D002074:Butanones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D003486:Cyanides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D005559:Formamides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008543:Melanins / Q000037:antagonists & inhibitors* / Q000096:biosynthesis; D015394:Molecular Structure; D010407:Penicillium / Q000378:metabolism*
chemical_list: D002074:Butanones; D003486:Cyanides; D005559:Formamides; D008543:Melanins; C484096:melanocin A; C484095:melanocin B; C484097:melanocin C