[Cardiovascular disease in HIV-infected patients on highly active antiretroviral therapy].
OBJECTIVE
Our goal was to assess the main characteristics of cardiovascular disease in HIV-infected patients on highly active antiretroviral therapy (HAART).


METHODS
Retrospective analysis of the clinico-epidemiological characteristics of 16 HIV-infected patients treated with HAART who had suffered a cardiovascular event from a 1,459 patients' cohort.


RESULTS
Clinical presentation of cardiovascular disease was an acute coronary syndrome in 12 cases, ischemic stroke in 2 and peripheral vascular disease in 2. Patients included in the study had a mean of 3.2 cardiovascular risk factors, smoking and low HDL levels being the more prevalent risk factors. Eight (50%, 95% CI, 25-75%) patients fulfilled the criteria of metabolic syndrome. The mean CD4 count was 548 x 10(6)/l.


CONCLUSIONS
HIV-infected patients on HAART ha-ve a high cardiovascular risk. A strict management of modifiable risk factors must be warranted in these patients.
Jericó
Carlos
C
Servicio de Medicina Interna-Enfermedades Infecciosas, Hospital del Mar, Universidad Autónoma de Barcelona, Spain.
Knobel
Hernando
H
Carmona
Alexia
A
Sorli
M Luisa
ML
López-Colomés
José Luis
JL
Pedro-Botet
Juan
J
D000328:Adult; D000368:Aged; D023241:Antiretroviral Therapy, Highly Active; D002318:Cardiovascular Diseases / Q000150:complications* / Q000517:prevention & control; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D015497:HIV-1; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors