title: Expression of galectin 4 in the rat small intestine during postnatal development.
abstract: We determined the expression of an endogenous lectin, galectin 4, in the rat small intestine during postnatal development. The mRNA levels of galectin 4 did not change significantly between birth and adulthood. In contrast, the protein was present at higher levels after than before weaning, and the potential ligands for galectin 4 were more highly represented in the enterocyte microvilli of weaned than of suckling rats. These results suggest possible differences either in galectin 4 mRNA stability, in its translation regulation or in the protein stability.
authors.affiliation: Département de Biochimie, Faculté de Médecine Lyon-Sud, Unité Inserm 189, alliée CNRS, BP 12, 69600 Oullins, France.
authors.forename: Elodie
authors.initials: E
authors.lastname: Niepceron
authors.forename: Fabienne
authors.initials: F
authors.lastname: Simian
authors.forename: Pierre
authors.initials: P
authors.lastname: Louisot
authors.forename: Marie-Claire
authors.initials: MC
authors.lastname: Biol-N'garagba
mesh_terms: D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D000833:Animals, Suckling; D037541:Galectin 4 / Q000032:analysis / Q000096:biosynthesis* / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental; D007413:Intestinal Mucosa / Q000737:chemistry; D007421:Intestine, Small / Q000737:chemistry / Q000254:growth & development* / Q000378:metabolism*; D008297:Male; D008871:Microvilli / Q000737:chemistry; D012333:RNA, Messenger / Q000032:analysis / Q000096:biosynthesis; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D037541:Galectin 4; D012333:RNA, Messenger