title: [Clinical usefulness of thallium-201 single-photon emission CT in the patient with hypertrophic cranial pachymeningitis].
abstract: We report a 54-year-old female with rheumatoid factor-positive hypertrophic cranial pachymeningitis. At age of 51 years she developed headache, hearing loss, right vagal nerve palsy, and right accessory nerve palsy. MRI revealed thickening and gadolinium-enhancement of the cranial dura mater. The initial symptoms significantly improved with corticosteroid therapy. Two years later, she presented with severe headache and neck pain. Although gadolinium-enhanced MR images failed to show any change compared with those before recurrence, 201Tl single-photon emission CT (SPECT) showed a remarkable accumulation of thallium-201 in the dura mater. Furthermore, the abnormal uptake of thallium-201 returned to normal after treatment with corticosteroid. 201T1-SPECT was a useful tool for the evaluation of disease activity in the patient with hypertrophic pachymeningitis.
authors.affiliation: Department of Neurology, Tokyo Metropolitan Neurological Hospital, 2-6-1 Musashidai, Fuchu, Tokyo 183-0042, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Suzuki
authors.forename: Reiji
authors.initials: R
authors.lastname: Koide
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Kagamihara
authors.forename: Akira
authors.initials: A
authors.lastname: Yagishita
authors.forename: Hideaki
authors.initials: H
authors.lastname: Hayashi
mesh_terms: D004388:Dura Mater / Q000473:pathology*; D005260:Female; D006801:Humans; D006984:Hypertrophy; D008279:Magnetic Resonance Imaging; D008581:Meningitis / Q000000981:diagnostic imaging*; D008875:Middle Aged; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D013794:Thallium Radioisotopes