title: A new nucleophilic addition/ring-closure sequence. Enantioselective synthesis of 3-deoxy-8-oxatropanes.
abstract: [reaction: see text] A study of new nucleophilic addition/ring-closure (NARC) sequences has resulted in the development of a stereoselective synthetic route to 3-deoxy-8-oxatropanes. The new sequences consisted of either a syn or anti aldol addition, employing an omega-alkenoyl sultam, followed by two-step bicyclic ring construction involving, consecutively, ring-closing metathesis and intramolecular oxymercuration.
authors.affiliation: School of Chemistry, Monash University, PO Box 23, Victoria 3800, Australia. patrick.perlmutter@sci.monash.edu.au
authors.forename: Giang
authors.initials: G
authors.lastname: Nguyen
authors.forename: Patrick
authors.initials: P
authors.lastname: Perlmutter
authors.forename: Mark L
authors.initials: ML
authors.lastname: Rose
authors.forename: Filisaty
authors.initials: F
authors.lastname: Vounatsos