Partitioning the work-sparing effects of partial ventilatory support in airflow obstruction.
Sweeping conclusions regarding the utility or nonutility of elevating expiratory pressure are not warranted. The effects of manipulating airway pressure in the setting of airflow obstruction depend heavily on the nature and severity of disease, as well as on the presence of airflow limitation during tidal breathing.
Marini
John J
JJ
University of Minnesota, USA. john.j.marini@healthpartners.com
D000818:Animals; D001986:Bronchial Spasm / Q000139:chemically induced / Q000628:therapy*; D004285:Dogs; D006801:Humans; D023421:Models, Animal; D011175:Positive-Pressure Respiration; D015656:Respiratory Mechanics / Q000502:physiology*; D014939:Work of Breathing / Q000502:physiology*