Determination of urea, glucose, and phosphate in dialysate with Fourier transform infrared spectroscopy.
Individual control and quantification of phosphate removal is desirable in dialysis treatment. Currently, no on-line method exists to quantify phosphate removal. We demonstrate that a multivariate calibration model based on infrared transmission spectra is capable of predicting phosphate, urea, and glucose concentrations at clinically relevant levels. The on-line monitoring of these components by infrared spectroscopy is therefore feasible.
Jensen
Peter Snoer
PS
Department of Physics, Lund Institute of Technology, Lund, Sweden. peter.snoer.jensen@risoe.dk
Bak
Jimmy
J
Ladefoged
Søren
S
Andersson-Engels
Stefan
S
D000368:Aged; D002138:Calibration; D005947:Glucose / Q000032:analysis*; D006801:Humans; D007259:Infrared Rays; D007668:Kidney / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000032:analysis*; D006435:Renal Dialysis; D013053:Spectrophotometry; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods*; D013997:Time Factors; D014508:Urea / Q000032:analysis*
D010710:Phosphates; D014508:Urea; D005947:Glucose