[Experimental study on effect of the water extract of dogwood fruits on the liver and testis in rats model of kidney-yang deficiency].
OBJECTIVE
To explore the effect of Dogwood fruits on tonifying kidney-yang.


METHODS
The effect of the water extract of Dogwood fruits on rats model of kidney-yang deficiency with the hydrocortisone was observed.


RESULTS
The water extract of Dogwood fruits could make normal the liver weight, and mitigate hepatocyte pathologic changes, increase the heptocellular levels of RNA and hepatin, and decrease the malondialdehyde (MDA) in rats model of kidney-yang deficiency. It could also make the viscera quotiety return to normal way and increase the levels of RNA in the interstitial cells of testicle in rats model of kidney-yang deficiency.


CONCLUSIONS
Water extract of Dogwood fruits can protect and improve the functions of the liver and testicle in rats model of kidney-yang deficiency.
Li
Chun-sheng
CS
Xiyuan Hospital, China Academy of TCM, Beijing 100091, China.
Zhang
Guo-xi
GX
Shi
Ti-ren
TR
Dong
Xiao-xia
XX
Sun
Pi
P
Li
Dian-dong
DD
Xu
Hong-zhang
HZ
Chen
Ke-ji
KJ
D000818:Animals; D029768:Cornus / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry; D006854:Hydrocortisone; D007674:Kidney Diseases / Q000139:chemically induced / Q000378:metabolism / Q000473:pathology*; D008099:Liver / Q000378:metabolism / Q000473:pathology*; D008112:Liver Glycogen / Q000378:metabolism; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D010946:Plants, Medicinal / Q000737:chemistry; D012313:RNA / Q000378:metabolism; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D013737:Testis / Q000378:metabolism / Q000473:pathology*; D016711:Yang Deficiency / Q000139:chemically induced / Q000378:metabolism / Q000473:pathology*
D004365:Drugs, Chinese Herbal; D008112:Liver Glycogen; D008315:Malondialdehyde; D012313:RNA; D006854:Hydrocortisone