Bioactive peptides from marine sources: pharmacological properties and isolation procedures.
Marine organisms represent a valuable source of new compounds. The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited resource of new active substances in the field of the development of bioactive products. In this paper, the molecular diversity of different marine peptides is described as well as information about their biological properties and mechanisms of action is provided. Moreover, a short review about isolation procedures of selected bioactive marine peptides is offered. Novel peptides from sponges, ascidians, mollusks, sea anemones and seaweeds are presented in association with their pharmacological properties and obtainment methods.
Aneiros
Abel
A
Centre of Marine Bioactive Substances (CEBIMAR), Ministry of Science Technology and Environment, PO Box 10600, Loma y 37, Alturas del Vedado, Ciudad, Habana, Cuba. cebimar@infomed.sld.cu
Garateix
Anoland
A
D000595:Amino Acid Sequence; D000818:Animals; D008386:Marine Biology; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D017386:Sequence Homology, Amino Acid
D010455:Peptides