The mean pulse rate pressure (mPRP) is an accurate parameter to assist in the efficacy of management of cerebrovascular disease cases with hypertension.
1121 cases of patients with cerebrovascular disease (CVD) and non-CVD (NCVD) were evaluated by sex and age groups for the clinical differences between mean arterial blood pressure (MAP) and it's double product, mean pulse rate pressure (mPRP = MAP x pulse rate). Two treatment arms were also compared. One group were given antihypertensive agent therapy (AHA), while the others were given lifestyle modification (LSM). In the AHA group, the mean values of blood pressure upper limit (UL) calculated by MAP and the UL and lower limit (LL) calculated by the mPRP in the females and older (> or = 60 years) age groups were significantly lower compared to those in the LSM arm of therapy. The same results were found in the UL calculated by mPRP in males and the younger (< 60 years) age group. The threshold indexes (TI) calculated by MAP and mPRP were never below 1.4 and 2.0 respectively. We conclude that in managing patients suffering from CVD with hypertension, the mPRP produced more detailed information in comparison to the MAP.
Lau
Alan H C
AH
Hypertensive Care Unit, Kyusyu Rosai Hospital, Japan.
D000367:Age Factors; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory; D002561:Cerebrovascular Disorders / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology* / Q000628:therapy*; D008019:Life Style; D008297:Male; D008875:Middle Aged; D012737:Sex Factors
D000959:Antihypertensive Agents