title: Sol-gel preparation and in vitro test of fluorapatite/hydroxyapatite films.
abstract: Fluorapatite/hydroxyapatite (FA/HA) films have been demonstrated to be a good alternative to pure hydroxyapatite (HA) ones in medical applications because of their bioactivity and relatively low solubility. In this study, Ca(NO(3))(2), P(2)O(5), and HPF(6) were used to prepare FA/HA films on Ti6Al4V substrate with the use of a sol-gel method. The F contents in the films could be tailored by adjusting the amount of HPF(6) added. The in vitro evaluation of the films was carried out in both SBF9# solution and TRIS buffer solution. The films with appropriate F contents showed a better ability to induce calcium phosphate deposition on their surfaces than either pure HA film and FA/HA films with even higher F content, as well as smaller dissolution amounts than HA film in TRIS buffer solution. Hence, the FA/HA films obtained in this work integrate both good bioactivity and stability, and could be a better choice for bioactive film on titanium alloys to produce high-quality implants.
authors.affiliation: Department of Material Science and Engineering, Zhejiang University Hangzhou, 310027, China.
authors.forename: Kui
authors.initials: K
authors.lastname: Cheng
authors.forename: Wenjian
authors.initials: W
authors.lastname: Weng
authors.forename: Haibo
authors.initials: H
authors.lastname: Qu
authors.forename: Piyi
authors.initials: P
authors.lastname: Du
authors.forename: Ge
authors.initials: G
authors.lastname: Shen
authors.forename: Gaorong
authors.initials: G
authors.lastname: Han
authors.forename: Juan
authors.initials: J
authors.lastname: Yang
authors.forename: J M F
authors.initials: JM
authors.lastname: Ferreira
mesh_terms: D001031:Apatites / Q000737:chemistry*; D001672:Biocompatible Materials / Q000737:chemistry*; D002021:Buffers; D017886:Durapatite / Q000737:chemistry*; D005782:Gels / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D044367:Phase Transition; D012995:Solubility; D013997:Time Factors
chemical_list: D001031:Apatites; D001672:Biocompatible Materials; D002021:Buffers; D005782:Gels; D017886:Durapatite; C025105:fluorapatite