[Experimental studies on the diel rhythm changes of blood cAMP in growthing rats after mandibular retraction].
OBJECTIVE
To document the effect of orthopedic therapy on the metabolism of rats.


METHODS
Exerting backwards force on rats mandible and measuring concentration of rats' blood cAMP in three groups with radio-immunity. Drawing the time-concentration curve and making cosine analysis.


RESULTS
In natural state, there was a diel rhythm change of concentration of cAMP in rats' blood(P<0.05); After being imposed orthopedic forces to inhibit mandibular growth, the normal diel rhythm of cAMP in blood still existed(P<0.05). The results of parameter-comparison among groups were more complicated.


CONCLUSIONS
Further research is needed to clarify the mechanism whether local orthopedic forces influence the body metabolism.
Lou
X H
XH
Department of Dentistry, Shanghai Seventh People's Hospital, Shanghai 200137, China.
Chen
Y X
YX
Chen
J H
JH
Ye
L
L