title: Evaluation of a new continuous cardiac output monitor in off-pump coronary artery surgery.
abstract: We evaluated a new, ultra-fast response continuous cardiac output monitor in 34 adult patients undergoing off-pump coronary artery bypass graft surgery. Cardiac output was measured with the TruCCOMS continuous cardiac output monitor (Aortech International plc, Lanarkshire, UK), using triplicate cold bolus thermodilution as the criterion standard, at fixed time points during surgery and during dobutamine infusion. The two techniques were compared using linear regression and Bland-Altman analysis. Overall, the study device displayed a bias of 0.4 l.min(-1) with limits of agreement of +2.5 l.min(-1) and -1.7 l.min(-1). The study device failed to detect the change in cardiac output caused by dobutamine accurately (y = 0.18x + 0.45; r(2) = 0.13), with an error linearly related to the magnitude of the change measured. We conclude that the device's failure to detect changes in cardiac output could be a major limitation in its clinical use in its current form.
authors.affiliation: Department of Anaesthesiology, University Hospitals, Katholieke Universiteit Leuven, Herestraat 49, B-3000 Leuven, Belgium.
authors.forename: H A
authors.initials: HA
authors.lastname: Leather
authors.forename: A
authors.initials: A
authors.lastname: Vuylsteke
authors.forename: C
authors.initials: C
authors.lastname: Bert
authors.forename: W
authors.initials: W
authors.lastname: M'Fam
authors.forename: P
authors.initials: P
authors.lastname: Segers
authors.forename: P
authors.initials: P
authors.lastname: Sergeant
authors.forename: E
authors.initials: E
authors.lastname: Vandermeersch
authors.forename: P F
authors.initials: PF
authors.lastname: Wouters
mesh_terms: D000368:Aged; D002302:Cardiac Output / Q000187:drug effects; D002315:Cardiopulmonary Bypass; D002316:Cardiotonic Agents / Q000494:pharmacology; D001026:Coronary Artery Bypass / Q000379:methods*; D004280:Dobutamine / Q000494:pharmacology; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000295:instrumentation*; D015203:Reproducibility of Results; D013815:Thermodilution
chemical_list: D002316:Cardiotonic Agents; D004280:Dobutamine