title: SARS: hospital infection control and admission strategies.
abstract: Nosocomial clustering with transmission to health care workers, patients and visitors is a prominent feature of severe acute respiratory syndrome (SARS). Hospital outbreaks of SARS typically occurred within the first week after admission of the very first SARS cases when the disease was not recognized and before isolation measures were implemented. In the majority of nosocomial infections, there was a history of close contact with a SARS patient, and transmission occurred via large droplets, direct contact with infectious material or by contact with fomites contaminated by infectious material. In a few instances, potential airborne transmission was reported in association with endotracheal intubation, nebulised medications and non-invasive positive pressure ventilation of SARS patients. In all SARS-affected countries, nosocomial transmission of the disease was effectively halted by enforcement of routine standard, contact and droplet precautions in all clinical areas and additional airborne precautions in the high-risk areas. In Hong Kong, where there are few private rooms for patient isolation, some hospitals have obtained good outcome by having designated SARS teams and separate wards for patient triage, confirmed SARS cases and step-down of patients in whom SARS had been ruled out. In conclusion, SARS represents one of the new challenges for those who are involved in hospital infection control. As SARS might re-emerge, all hospitals should take advantage of the current SARS-free interval to review their infection control programmes, alert mechanisms, response capability and to repair any identified inadequacies.
authors.affiliation: Department of Microbiology, Queen Mary Hospital, University of Hong Kong, Hong Kong, China.
authors.forename: Pak-Leung
authors.initials: PL
authors.lastname: Ho
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Tang
authors.forename: Wing-Hong
authors.initials: WH
authors.lastname: Seto
mesh_terms: D000465:Algorithms; D003428:Cross Infection / Q000517:prevention & control*; D006723:Hong Kong; D006801:Humans; D017053:Infection Control / Q000379:methods*; D010343:Patient Admission; D045169:Severe Acute Respiratory Syndrome / Q000517:prevention & control*; D014218:Triage