title: Nine-year incidence of lens opacities in the Barbados Eye Studies.
abstract: OBJECTIVE
  To provide 9-year cumulative incidence of age-related lens opacities in a predominantly black population.
  
  
  METHODS
  Population-based cohort study, after 9 years of follow-up (n = 2793; 81% participation).
  
  
  METHODS
  Nine-year cumulative incidence and progression of lens opacities, by type, based on the Lens Opacities Classification System II at the slit lamp.
  
  
  RESULTS
  Black participants had a higher 9-year incidence of overall lens changes than white participants (age- and gender-adjusted relative risk [RR], 1.8; 95% confidence interval [CI], 1.2-2.8), as well as of cortical opacities (RR, 3.2; 95% CI, 1.7-6.2). In black participants, incidence rates of any cortical and any nuclear opacities were 33.8% and 42.0%, respectively, and higher than for any posterior subcapsular (PSC) opacities (6.3%). The incidence increased with age for all 3 types, and women had a higher risk of cortical and nuclear opacities (P<0.05). Single cortical opacities were the most frequent type to develop by the 9-year follow-up (23.2%), followed by nuclear-only opacities (17.1%) and mixed opacities (15.3%). Progression rates of pre-existing opacities were 22.0% for cortical, 17.8% for nuclear, and 25.8% for PSC opacities.
  
  
  CONCLUSIONS
  The 9-year follow-up of this cohort indicated a high incidence and progression of cortical and nuclear opacities, highlighting the public health importance of cataract in black populations.
authors.affiliation: Department of Preventive Medicine, School of Medicine, Stony Brook University, HSC L3 Room 086, Stony Brook, NY 11794-8036, USA. cleske@notes.cc.sunysb.edu
authors.forename: M Cristina
authors.initials: MC
authors.lastname: Leske
authors.forename: Suh-Yuh
authors.initials: SY
authors.lastname: Wu
authors.forename: Barbara
authors.initials: B
authors.lastname: Nemesure
authors.forename: Ling
authors.initials: L
authors.lastname: Yang
authors.forename: Anselm
authors.initials: A
authors.lastname: Hennis
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D001460:Barbados / Q000453:epidemiology; D044383:Black People; D002386:Cataract / Q000208:ethnology* / Q000503:physiopathology; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007908:Lens, Crystalline / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D017678:Sex Distribution; D044465:White People