title: [Expression of testosterone in the rapid growing rat condylar cartilage and the expression changes after the function mandibular advancement].
abstract: OBJECTIVE
  To investigate the expressions of Testosterone in the condylar cartilage of rapid growing rats.
  
  
  METHODS
  The mimic functional appliances were used in experiment groups and rats were killed after 3 days, 1 week, 2 weeks, 3 weeks and 4 weeks. Immunohistochemical technique was used to detect the expression of T.
  
  
  RESULTS
  T was expressed throughout the condylar cartilage. The Highest expressions were in mature layers of both experiment and control groups. Along with the maturation, the expressions of T in the condylar cartilage were changed respectively, and the immunostain levels in the mature layer of experiment groups 2 and 3 weeks were higher than those of control groups (P < 0.05).
  
  
  CONCLUSIONS
  1. T is a member of cartilage growth and development control system. 2. The orthopedic mechanism of functional appliance may be conducted by T.
authors.affiliation: Dept. of Orthodontics, West China College of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: Xiao-bin
authors.initials: XB
authors.lastname: Li
authors.forename: Kai-yun
authors.initials: KY
authors.lastname: Chen
authors.forename: Zheng
authors.initials: Z
authors.lastname: Zhou
authors.forename: Song-jiao
authors.initials: SJ
authors.lastname: Luo
mesh_terms: D000818:Animals; D002356:Cartilage / Q000254:growth & development / Q000378:metabolism*; D008297:Male; D019186:Mandibular Advancement; D008335:Mandibular Condyle / Q000254:growth & development / Q000378:metabolism*; D017289:Orthodontic Appliances, Functional; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013739:Testosterone / Q000378:metabolism*
chemical_list: D013739:Testosterone