title: Contribution for an African autosomic STR database (AmpF/STR Identifiler and Powerplex 16 System) and a report on genotypic variations.
abstract: Allele frequencies, together with some parameters of forensic interest, for 17 STRs included in the AmpF/STR Identifiler (CSF1PO, D2S1338, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, FGA, TH01, TPO and VWA) and Powerplex 16 System (CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, Penta D, Penta E, TH01, TPO and VWA) were estimated from a sample of 135-144 unrelated individuals from Mozambique. No deviations from Hardy-Weinberg equilibrium were observed with the exception of the FGA locus (using the Bonferroni correction for the number of loci analysed, the departure observed at this locus was not significant). Comparative analyses between our population data and other African databases, namely Promega's African-Americans, AB Applied Biosystems African-Americans and two other population samples from Mozambique and Guiné Bissau, are presented and discussed. Genotype inconsistencies between both commercial kits (for D16S539 and D8S1179) and other genotypic variations (three-banded allele patterns for TPO) are also reported.
authors.affiliation: Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal. calves@ipatimup.pt
authors.forename: Cíntia
authors.initials: C
authors.lastname: Alves
authors.forename: Leonor
authors.initials: L
authors.lastname: Gusmão
authors.forename: Albertino
authors.initials: A
authors.lastname: Damasceno
authors.forename: Benilde
authors.initials: B
authors.lastname: Soares
authors.forename: António
authors.initials: A
authors.lastname: Amorim
mesh_terms: D044383:Black People / Q000235:genetics*; D016172:DNA Fingerprinting / Q000379:methods; D005787:Gene Frequency; D014644:Genetic Variation; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D009073:Mozambique; D016133:Polymerase Chain Reaction / Q000379:methods*; D020080:Tandem Repeat Sequences; D001741:Black or African American