[Sentinel lymph-node biopsy in breast cancer: five years' experience].
The authors report on their experience with sentinel lymph-node biopsy in breast cancer. Sentinel lymph-node biopsy was performed in 91 patients with T1-T2 N0 M0 breast cancer using radiocolloid (99mTC radiolabelled colloidal human albumin microaggregate) injected perilesionally in 56 cases and by Blu Patent V alone in 35 cases. The sentinel lymph nodes identified were located in the axilla in 88 cases, in the internal mammary nodes in 2 cases and in a subclavicular site in 1 case. The histological examination was negative in 62 cases and positive in 29; Axillary lymph-node dissection was carried out in node-positive cases. No recurrences were observed in any of the cases treated. Lymphatic mapping and sentinel lymphadenectomy in primary breast cancer is now a feasible and useful method of avoiding routine axillary lymphadenectomy. However, the role of micro- or macrometastases in sentinel lymph nodes and the significance of identification of tumour mRNA have yet to be defined.
Gioffrè Florio
Maria Antonietta
MA
Cattedra di Chirurgia Generale dell'Università degli Studi di Messina.
Famà
Fausto
F
Gullo
Grazia
G
Pollicino
Andrea
A
Scarfò
Paola
P
D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D021701:Sentinel Lymph Node Biopsy; D013997:Time Factors