Devic disease and thymoma with anti-central nervous system and antithymus antibodies.
A patient with myasthenia gravis and thymoma developed neuromyelitis optica (NMO) and necrotizing myositis 4 months after treatment of the tumor. Antibodies reacting with the CNS and thymic epithelial cells were detected in the serum during the acute phase of NMO, suggesting that the NMO was linked to the thymoma.
Antoine
J C
JC
Service de Neurologie and EA 3062, Etablissement Français du Sang and EA 3062, France.
Camdessanché
J P
JP
Absi
L
L
Lassablière
F
F
Féasson
L
L
D000818:Animals; D001323:Autoantibodies / Q000097:blood*; D002490:Central Nervous System / Q000276:immunology*; D002531:Cerebellum / Q000276:immunology; D006801:Humans; D007150:Immunohistochemistry; D007159:Immunologic Tests; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications / Q000175:diagnosis / Q000276:immunology; D009220:Myositis / Q000150:complications / Q000175:diagnosis / Q000276:immunology; D009471:Neuromyelitis Optica / Q000150:complications / Q000175:diagnosis / Q000276:immunology*; D010951:Plasma Exchange; D051381:Rats; D013116:Spinal Cord / Q000276:immunology; D013945:Thymoma / Q000150:complications / Q000175:diagnosis / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology* / Q000473:pathology; D013953:Thymus Neoplasms / Q000150:complications / Q000175:diagnosis / Q000276:immunology*
D001323:Autoantibodies