title: [Prostatic cancer in a young adult: a report of 2 cases].
abstract: Patients younger than 45 years with prostate cancer are rare. Between 1999 and 2002, we studied two cases of prostate cancer in men aged under 45 years. Case 1; a 45-year-old man admitted with the chief complaint of urination disorder. Serum level of prostate-specific antigen (PSA) was 5,000 ng/ml or higher. Transrectal needle biopsy of the prostate revealed moderately differentiated adenocarcinoma. Computed tomography (CT) and bone scan showed para-aorta lymph node metastasis and bone metastasis. Hormone therapy was performed. Case 2; a 37-year-old man admitted with the chief complaint of pollakisuria and sense of residual urine. Serum level of prostate-specific antigen (PSA) was 24 ng/ml. Magnetic resonance imaging (MRI) showed that the prostate tumor invaded the bladder wall. Transrectal needle biopsy revealed poorly differentiated adenocarcinoma. Hormone therapy and radiation therapy were performed. Twenty-one cases reported in Japan in addition to the present cases are reviewed.
authors.affiliation: Department of Urology, Jikei University School of Medicine.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sasaki
authors.forename: Jyun
authors.initials: J
authors.lastname: Miki
authors.forename: Tarou
authors.initials: T
authors.lastname: Hasegawa
authors.forename: Norio
authors.initials: N
authors.lastname: Hasegawa
authors.forename: Isao
authors.initials: I
authors.lastname: Ikemoto
authors.forename: Yukihiko
authors.initials: Y
authors.lastname: Ohishi
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D000328:Adult; D000367:Age Factors; D014408:Biomarkers, Tumor / Q000097:blood; D003131:Combined Modality Therapy; D003952:Diagnostic Imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy
chemical_list: D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen