Selecting cryopreserved semen for assisted reproductive techniques based on the level of sperm nuclear DNA fragmentation resulted in pregnancy.
A cryopreserved sperm sample with a low level of DNA fragmentation was used for intracytoplasmic sperm injection and resulted in a twin birth from a couple with a 10-year history of idiopathic infertility.
Alvarez
Juan G
JG
Ollero
Mario
M
Larson-Cook
Kjersten L
KL
Evenson
Donald P
DP
D002467:Cell Nucleus / Q000502:physiology; D015925:Cryopreservation; D053938:DNA Fragmentation; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D027724:Reproductive Techniques, Assisted; D012661:Semen; D013094:Spermatozoa / Q000502:physiology*