title: [An experiment to study the treatment of sarcomas by electroporation].
abstract: In this paper is reported a new approach for the treatment of sarcoma--electroporation therapy. Electroporation can accelerate pharmacal molecules into cytoplasm by transient electromagnetic pulses. We have utilized the phenomenon of electroporation treating the S-180 sarcomas in the hind legs of the Kunming mice by intratumoral injection of anti-tumor agent at low dose. From the experiment, we learned that this approach can bring about remarkable effect. The technical procedure is easy to do and easy to control. Especially, it is useful in curing the flat tumor and has little untoward side effect. It deserves to be recommended as a new approach to treating the tumor in clinics.
authors.affiliation: School of Electronic Engineering and Information, Sichuan University, Chengdu 610064, China. scu.zh@sohu.com
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
authors.forename: Baoyi
authors.initials: B
authors.lastname: Wang
authors.forename: Haichuan
authors.initials: H
authors.lastname: Chen
authors.forename: Zishu
authors.initials: Z
authors.lastname: Wang
authors.forename: Kong
authors.initials: K
authors.lastname: Yang
authors.forename: Jingru
authors.initials: J
authors.lastname: Sun
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use; D017209:Apoptosis / Q000187:drug effects; D045744:Cell Line, Tumor; D003520:Cyclophosphamide / Q000627:therapeutic use; D053672:Electrochemotherapy / Q000379:methods*; D051379:Mice; D009368:Neoplasm Transplantation; D012510:Sarcoma 180 / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents; D003520:Cyclophosphamide