[Validation of the Spanish version of the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ)].
OBJECTIVE
Validate the questionnaire Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) in conditions of regular clinical practice.


METHODS
Two hundred and eighty four adult patients with a diagnosis of rhinoconjunctivitis (RC) cared in 37 centers of specialized health care in allergy or otorhinolaryngology services in Spain were analyzed. Patients with RC were included in two groups: clinically non-stable patients who received treatment with an oral second generation antihistaminic (group A), and clinically stable patients (group B). Sociodemographic and clinical variables were collected and the questionnaires RQLQ and EQ-5D were administered in the initial visit and in the second visit 15 days after. Feasibility, validity, reliability and sensitivity related to the change of the RQLQ were analyzed.


RESULTS
The mean period (standard deviation) of administration was 9.67 (6.25) minutes and 85.6% of patients needed assistance in order to fill the RQLQ, especially the selection of the characteristics (62.5%). The dimensions of the RQLQ showed a greater association with the dimensions of the EQ-5D that assessed similar aspects and the symptoms in which a greater relation was expected. The alpha Cronbach coefficient of the scorings of the RQLQ fluctuated between 0.85 and 0.96 and the intraclass correlation coefficient fluctuated between 0.68 and 0.89. The sensitivity to the change of the dimensions of the RQLQ, evaluated through the magnitude of the effect between the two visits, ranged between 0.76 and 1.46.


CONCLUSIONS
The Spanish version of the RQLQ proved to be a valid instrument for assessing the Health-Related Quality of Life (HRQL) in adult patients with seasonal or perennial RC.
Soler
R
R
Hospital Son Dureta, Mallorca.
de la Hoz
B
B
Badia
X
X
Mercadal
J
J
Lozano
R
R
Benavides
A
A
Roset
M
M
D000203:Activities of Daily Living; D000293:Adolescent; D000328:Adult; D003231:Conjunctivitis / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D011788:Quality of Life; D015203:Reproducibility of Results; D012220:Rhinitis / Q000523:psychology*; D018434:Sickness Impact Profile; D012959:Socioeconomic Factors; D013030:Spain; D011795:Surveys and Questionnaires; D014177:Translations