Diastereospecific synthesis of phosphinidene-capped cyclodextrins leading to "introverted" ligands.
alpha-Cyclodextrins (alpha-CDs) containing "PPh" units which cap the primary face of the CD were obtained in high yield by reaction of Li(2)PPh with A,B- or A,C-dimesylated and A,B,D,E-tetramesylated precursors; the resulting phosphines are diastereomerically pure and constitute valuable precursors for the synthesis of metallo-cavitands.
Engeldinger
Eric
E
Laboratoire de Chimie Inorganique Moléculaire, UMR 7513, Université Louis Pasteur, 1 rue Blaise Pascal, F-67008 Strasbourg cedex, France.
Poorters
Laurent
L
Armspach
Dominique
D
Matt
Dominique
D
Toupet
Loïc
L
D002236:Carbohydrate Conformation; D003505:Cyclodextrins / Q000138:chemical synthesis*; D004988:Ethers, Cyclic / Q000138:chemical synthesis; D008024:Ligands; D008958:Models, Molecular; D010720:Phosphines / Q000138:chemical synthesis / Q000737:chemistry*; D012118:Resorcinols / Q000138:chemical synthesis; D013237:Stereoisomerism
D003505:Cyclodextrins; D004988:Ethers, Cyclic; D008024:Ligands; D010720:Phosphines; D012118:Resorcinols; C442939:cavitand