title: Estimation of doses to personnel and patients during endovascular brachytherapy applications.
abstract: In the last few years coronary endovascular brachytherapy using gamma- and beta-emitting radionuclides has been established as a standard treatment procedure to prevent restenosis after percutaneous coronary interventions. Direct measurements and calculations were made to determine personnel doses and organ doses of patients due to gamma rays of 192Ir and beta rays of 90Sr/90Y and 32P sources. In general, our results show that the dose levels are low compared with the X-ray exposure from angiography. The dose rate from bremsstrahlung at 1 m distance from a device containing a 90Sr/90Y source of 2.3 GBq is 4 micro Sv h(-1). The skin dose from beta rays during source transfer into and from the patient was estimated with the directional dose equivalent H'(0.07) of 10 micro Sv at 1 m distance from the catheter. By maintaining safe distances, the dose levels can be kept well within annual dose limits.
authors.affiliation: Department of Radiotherapy and Radiobiology, Medical University of Vienna, AKH Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria. christian.kirisits@meduniwien.ac.at
authors.forename: Christian
authors.initials: C
authors.lastname: Kirisits
authors.forename: Alfred
authors.initials: A
authors.lastname: Hefner
authors.forename: Paul
authors.initials: P
authors.lastname: Wexberg
authors.forename: Boris
authors.initials: B
authors.lastname: Pokrajac
authors.forename: Dietmar
authors.initials: D
authors.lastname: Glogar
authors.forename: Richard
authors.initials: R
authors.lastname: Pötter
authors.forename: Dietmar
authors.initials: D
authors.lastname: Georg
mesh_terms: D001610:Beta Particles; D001822:Body Burden; D001918:Brachytherapy / Q000009:adverse effects / Q000379:methods*; D005720:Gamma Rays; D006083:Graft Occlusion, Vascular / Q000517:prevention & control*; D006801:Humans; D009684:Nuclear Medicine Department, Hospital; D016273:Occupational Exposure / Q000032:analysis*; D009928:Organ Specificity; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000209:etiology / Q000517:prevention & control; D011835:Radiation Protection / Q000379:methods; D011868:Radioisotopes / Q000032:analysis* / Q000627:therapeutic use*; D011874:Radiometry / Q000379:methods*; D019275:Radiopharmaceuticals / Q000032:analysis / Q000627:therapeutic use; D011879:Radiotherapy Dosage; D018570:Risk Assessment / Q000379:methods*
chemical_list: D011868:Radioisotopes; D019275:Radiopharmaceuticals