title: A rapid presentation event-related functional magnetic resonance imaging study of response inhibition in macaque monkeys.
abstract: Rapid presentation event-related functional magnetic resonance imaging was applied to macaque monkeys performing a symmetrically rewarded go/no-go task, to investigate neural correlate of response inhibition. Sensorimotor activation related to the task performance was observed predominantly in the hemisphere contralateral to the response forelimb. Furthermore, no-go dominant activation possibly related to response inhibition, was observed in the ventral prefrontal cortex, in accordance with previous electrophysiological studies. These results show the feasibility of rapid presentation event-related functional magnetic resonance imaging in behaving monkeys.
authors.affiliation: Department of Physiology, The University of Tokyo School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
authors.forename: Masahito
authors.initials: M
authors.lastname: Morita
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Nakahara
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Hayashi
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D001931:Brain Mapping; D005071:Evoked Potentials / Q000502:physiology*; D007839:Functional Laterality; D008251:Macaca; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009433:Neural Inhibition / Q000502:physiology*; D010100:Oxygen / Q000097:blood; D017397:Prefrontal Cortex / Q000098:blood supply / Q000502:physiology; D011597:Psychomotor Performance / Q000502:physiology; D012201:Reward; D013997:Time Factors
chemical_list: D010100:Oxygen