title: [Livedoid vasculopathy with heterozygous factor V Leiden mutation and sticky platelet syndrome].
abstract: A 64-year-old male patient presented with painful ulcerations and livedo racemosa of both lower limbs. He had a history of cerebral and myocardial infarctions. Dermatohistologic findings and laboratory tests of the patient's coagulation system revealed the diagnosis of livedoid vasculopathy with heterozygous factor V Leiden mutation and sticky platelet syndrome type II. Systemic treatment with acetylsalicylic acid and heparin as well as topical therapy with disinfectant and granulation-inducing agents resulted in improvement of the skin lesions.
authors.affiliation: Hautklinik, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: V
authors.initials: V
authors.lastname: Lewerenz
authors.forename: T
authors.initials: T
authors.lastname: Burchardt
authors.forename: A
authors.initials: A
authors.lastname: Büchau
authors.forename: T
authors.initials: T
authors.lastname: Ruzicka
authors.forename: M
authors.initials: M
authors.lastname: Megahed
mesh_terms: D020016:Activated Protein C Resistance; D000925:Anticoagulants / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D001792:Blood Platelets; D005165:Factor V / Q000235:genetics*; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006493:Heparin / Q000627:therapeutic use; D006579:Heterozygote; D006801:Humans; D007871:Leg Ulcer / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D017354:Point Mutation; D012867:Skin / Q000473:pathology; D017445:Skin Diseases, Vascular / Q000188:drug therapy / Q000473:pathology; D013577:Syndrome
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors; C095381:factor V Leiden; D005165:Factor V; D006493:Heparin; D001241:Aspirin