Nephrotic syndrome as a result of membranous nephropathy caused by renal cell carcinoma.
A 77-year-old woman was admitted for a renal biopsy to evaluate a case of nephrotic syndrome. In the course of the examination, a right renal tumor was incidentally found. We performed a right radical nephrectomy in advance of the renal biopsy. Histologically, the tumor was diagnosed as a renal cell carcinoma (clear cell carcinoma) and the non-neoplastic renal cell tissue showed membranous nephropathy (MN). After surgery, the nephrotic syndrome remitted without any further medical treatment and the MN was considered to be a malignancy associated syndrome. There have been few case reports in the literature regarding this association and we wish to describe another case.
Kuroda
Isao
I
Department of Urology, Biomedical Research Center, Saitama Medical School, Saitama, Japan.
Ueno
Munehisa
M
Okada
Hirokazu
H
Shimada
Shiho
S
Akita
Masumi
M
Tsukamoto
Takuji
T
Deguchi
Nobuhiro
N
D000368:Aged; D002292:Carcinoma, Renal Cell / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D005260:Female; D015433:Glomerulonephritis, Membranous / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D009392:Nephrectomy; D009404:Nephrotic Syndrome / Q000209:etiology* / Q000601:surgery