Ganglioneurocytoma of the third ventricle.
We present a very rare case of an intracranial ganglioneurocytoma. This 57-year-old female patient noticed some concentration difficulties for about 5 months. Visual acuity was 80% on both sides. CT and MRI of her head demonstrated a 3 x 2.5 x 2.8 cm3 lesion within the third ventricle with inhomogenous enhancement of contrast medium. After a right pterional approach the tumor could be removed completely. Postoperatively there was a paresis of the oculomotor nerve on the right side and psychological changes. Histological examination revealed neuronal differentiation with neurocytes and small ganglionic cells and the tumor was graded as a ganglioneurocytoma (WHO grade II). Follow-up examination 6 months after the operation showed improvement of her third nerve paresis and of her neuropsychological deficits. MRI showed no recurrence.
Buhl
Ralf
R
Department of Neurosurgery, University of Kiel, Kiel, Germany. buhlr@nch.uni-kiel.de
Huang
Hongguang
H
Hugo
Heinz H
HH
Mehdorn
Hubertus M
HM
D014408:Biomarkers, Tumor / Q000032:analysis; D002551:Cerebral Ventricle Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D005260:Female; D005729:Ganglioneuroma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D020542:Third Ventricle / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed
D014408:Biomarkers, Tumor