title: Combined PET/CT with iodine-124 in diagnosis of spread metastatic thyroid carcinoma: a case report.
abstract: Iodine-124 positron emission tomography (PET) is a useful 3D imaging technique for diagnosis and management of thyroid diseases. The difficulty in interpretation of the PET scans with highly selective tracers, such as iodine-124, is the lack of identifiable anatomical structures, so an accurate anatomical localization of foci presenting abnormal uptake is problematic. Consequently, a combined PET/CT scanner can resolve these difficulties by co-registering PET and CT data in a single session allowing a correlation of functional and morphologic imaging. A case is presented where iodine-124 produced by a clinical cyclotron and FDG were used to acquire images with a combined PET/CT scanner for clinical staging. On the basis of the PET/CT exams the treatment of the patient was modified.
authors.affiliation: Clinic and Policlinic for Nuclear Medicine, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany. l.freudenberg@t-online.de
authors.forename: L S
authors.initials: LS
authors.lastname: Freudenberg
authors.forename: G
authors.initials: G
authors.lastname: Antoch
authors.forename: R
authors.initials: R
authors.lastname: Görges
authors.forename: J
authors.initials: J
authors.lastname: Knust
authors.forename: R
authors.initials: R
authors.lastname: Pink
authors.forename: W
authors.initials: W
authors.lastname: Jentzen
authors.forename: J F
authors.initials: JF
authors.lastname: Debatin
authors.forename: W
authors.initials: W
authors.lastname: Brandau
authors.forename: A
authors.initials: A
authors.lastname: Bockisch
authors.forename: J
authors.initials: J
authors.lastname: Stattaus
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000000981:diagnostic imaging* / Q000556:secondary*; D000368:Aged; D006801:Humans; D007457:Iodine Radioisotopes; D008207:Lymphatic Metastasis; D008297:Male; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D014055:Tomography, Emission-Computed / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D007457:Iodine Radioisotopes