Rasmussen encephalitis with active inflammation and delayed seizures onset.
Severe focal epilepsy is regarded as a clinical hallmark of Rasmussen encephalitis (RE). The authors report two children with progressive hemiparesis, contralateral hemispheric atrophy, and pathologic features characteristic for RE. At histologic diagnosis and over several months, neither patient experienced seizures. The report enlarges the clinical spectrum of RE and suggests that seizures are not an obligatory presenting symptom of the disorder.
Korn-Lubetzki
I
I
Neurological Service, Department of Pediatrics, Bikur Cholim Hospital, Jerusalem, Israel. ikl@md.huji.ac.il
Bien
C G
CG
Bauer
J
J
Gomori
M
M
Wiendl
H
H
Trajo
L
L
Ovadia
H
H
Wilken
B
B
Hans
V H
VH
Elger
C E
CE
Hurvitz
H
H
Steiner
I
I
D017668:Age of Onset; D001284:Atrophy / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D001706:Biopsy; D002648:Child; D018450:Disease Progression; D004569:Electroencephalography; D004660:Encephalitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D007839:Functional Laterality; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D066298:In Vitro Techniques; D008279:Magnetic Resonance Imaging; D008297:Male; D018908:Muscle Weakness / Q000209:etiology; D010291:Paresis / Q000188:drug therapy / Q000209:etiology; D012640:Seizures / Q000209:etiology*
D016756:Immunoglobulins, Intravenous