title: [Role of stabilizing and splitting selection in evolution of of viruses from the Parvoviridae and Astroviridae families].
abstract: We had previously collected and analyzed, by phylogenetic methods, all genetic data available now for the Parvoviridae and Astroviridae families, which made it possible to define the evolutionary relations between the viruses as well as to depict a variety of events in the evolutionary history of the two families. The offered case study is dedicated to investigating the stabilizing and splitting selection types in the evolution of the discussed viral families. We analyzed the number of synonymous and non-synonymous nucleotide substitutions in the coding genomes' regions of the viruses. Finally, the stabilizing selection was shown to be a key factor in the evolution of parvoviruses and astroviruses.
authors.forename: V V
authors.initials: VV
authors.lastname: Lukashov
authors.forename: J
authors.initials: J
authors.lastname: Goudsmit
mesh_terms: D000818:Animals; D019200:Astroviridae / Q000145:classification / Q000235:genetics*; D005075:Biological Evolution; D017992:Parvovirus / Q000145:classification / Q000235:genetics*