Positron emission tomography in central nervous system drug discovery and development.
Genetics, neuroscience, and imaging science have advanced greatly in the last few years. These advances can be brought together and applied in creative new ways to make available better drugs for treating neuropsychiatric disorders and for getting candidate drugs through the development process faster. One particular approach, built around [18F]fluordeoxyglucose positron emission tomography, is described.
Cooper
Malcolm
M
Department of Radiology, University of Chicago, 2843 West Rascher, Chicago, IL 60625, USA.
Metz
John
J
D000818:Animals; D002490:Central Nervous System / Q000000981:diagnostic imaging* / Q000187:drug effects*; D002491:Central Nervous System Agents / Q000494:pharmacology*; D015195:Drug Design; D006801:Humans; D014055:Tomography, Emission-Computed
D002491:Central Nervous System Agents