Effects of Alzheimer disease on memory for verbal emotional information.
In healthy young and older adults, emotional information is often better remembered than neutral information. It is an open question, however, whether emotional memory enhancement is blunted or preserved in Alzheimer disease (AD). Prior studies of emotional memory in AD have included small samples of patients. In addition, studies that failed to find an enhancement effect in AD used stimuli lacking semantic coherence (e.g. lists of unrelated words, some that were emotional and others that were neutral). To circumvent these limitations, the present study examined a large number of AD patients (N=80) and investigated whether AD patients would show better memory for a verbal description of an emotional event as compared to a neutral one. AD patients were equivalent to young and older control participants in rating the emotional descriptions for valence and arousal. Unlike the control groups, however, memory in AD patients did not benefit from the emotional narratives. We conclude that AD disrupts memory enhancement for at least some types of verbal emotional information.
Kensinger
Elizabeth A
EA
Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, MIT Building NE20-392, 77 Massachusetts Avenue, Cambridge, MA 02138, USA. ekensing@alum.mit.edu
Anderson
Alberta
A
Growdon
John H
JH
Corkin
Suzanne
S
D000328:Adult; D000339:Affect / Q000502:physiology*; D000368:Aged; D000375:Aging / Q000502:physiology*; D000544:Alzheimer Disease / Q000503:physiopathology*; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology*; D008875:Middle Aged; D012016:Reference Values; D014706:Verbal Learning / Q000502:physiology*