title: Regioselective oxidation of 2-amino-3-aroyl-4,5-dialkylthiophenes by DMSO.
abstract: Solutions of 2-amino-3-aroyl-4,5-dialkylthiophenes in DMSO (dimethyl sulfoxide) undergo regioselective oxidation of benzylic carbon under mild conditions. We describe three examples and propose a mechanism for oxidation.
authors.affiliation: Department of Chemistry, University of Virginia, Charlottesville, VA 22901, USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Joshi
authors.forename: Mahendra D
authors.initials: MD
authors.lastname: Chordia
authors.forename: Timothy L
authors.initials: TL
authors.lastname: Macdonald
authors.forename: Joel
authors.initials: J
authors.lastname: Linden
authors.forename: Ray
authors.initials: R
authors.lastname: Olsson
mesh_terms: D004121:Dimethyl Sulfoxide / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013876:Thiophenes / Q000737:chemistry*
chemical_list: C490859:ATL-525; C490858:ATL-527; D013876:Thiophenes; C075004:PD 81723; D004121:Dimethyl Sulfoxide