Can the clock be turned back on ovarian aging?
A basic tenet of reproductive biology is that female mammals are born with a set number of germ cells (oocytes). A new study by Johnson et al. challenges these beliefs by demonstrating that the postnatal mouse ovary contains actively dividing germ cells. These findings have implications for prolonging the reproductive life span of women.
Hoyer
Patricia B
PB
Department of Physiology, University of Arizona, Tucson, AZ 85721, USA. hoyer@u.arizona.edu
D000375:Aging / Q000502:physiology*; D000818:Animals; D005260:Female; D006801:Humans; D008593:Menopause / Q000502:physiology; D051379:Mice; D009865:Oocytes / Q000254:growth & development; D006080:Ovarian Follicle / Q000502:physiology; D010053:Ovary / Q000502:physiology*; D012098:Reproduction / Q000502:physiology