[Potentialities of calcium dependent lectin receptors of antigen presenting cells for the immunotherapeutic preparation development].
Publications on C-lectin receptors, multifunctional surface molecules of antigen presenting cells are updated. The study of C-lectin receptors is stipulated by their role in antimicrobial protection. The importance of C-lectin receptors of dendrite cells in the system of the recognition of microbial carbohydrate as well as their properties of the targeted supply of tumor cell and other antigens to dendrite cells with the purpose of the formation of immunity against faintly immunogenic antigens is considered. Suggestion is made on the potential of their use as experimental preparations for immunotherapy.
Del'vig
A A
AA
Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia.
Semenov
B F
BF
D000818:Animals; D017951:Antigen Presentation; D000938:Antigen-Presenting Cells / Q000276:immunology* / Q000378:metabolism; D000951:Antigens, Neoplasm / Q000276:immunology / Q000378:metabolism; D002118:Calcium; D002454:Cell Differentiation; D002465:Cell Movement; D003713:Dendritic Cells / Q000276:immunology* / Q000378:metabolism; D006801:Humans; D007167:Immunotherapy; D037181:Lectins, C-Type / Q000502:physiology* / Q000627:therapeutic use; D011135:Polysaccharides, Bacterial / Q000276:immunology / Q000378:metabolism; D011971:Receptors, Immunologic / Q000502:physiology / Q000627:therapeutic use
D000951:Antigens, Neoplasm; D037181:Lectins, C-Type; D011135:Polysaccharides, Bacterial; D011971:Receptors, Immunologic; D002118:Calcium