Molecular mechanisms of epithelial polarity: about shapes, forces, and orientation problems.
In a variety of organs, epithelial cells assemble into networks of cysts and tubules. Such structures can be reproduced in vitro. Here the importance of plasma membrane compartmentalization and forces that drive morphogenetic events during cystogenesis are discussed.
Kroschewski
Ruth
R
Institute of Biochemistry, Swiss Federal Institute of Technology Zürich, 8093 Zürich, Switzerland.
D000818:Animals; D002451:Cell Compartmentation / Q000502:physiology*; D016764:Cell Polarity / Q000502:physiology*; D004847:Epithelial Cells / Q000166:cytology* / Q000502:physiology*; D006801:Humans