Lewis acid-mediated cycloaddition of methylenecyclopropanes with aldehydes and imines: a facile access to indene, THF, and pyrrolidine skeletons via homoallylic rearrangement protocol.
Methylenecyclopropanes (MCPs) 1 can react with aldehydes and aldimines to give the corresponding indene, THF, and pyrrolidine cycloaddition products in the presence of BF(3).OEt(2) under mild reaction conditions.
Shi
Min
M
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China. mshi@pub.sioc.ac.cn
Xu
Bo
B
Huang
Jin-Wen
JW