Lacrimal location of sinus histiocytosis (Rosai-Dorfman-Destombes disease).
A 7-year-old West African male patient presented with recurrence of multiple cervical lymphadenopathy. Cervical node biopsy disclosed a sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman-Destombes disease). During follow-up, the patient developed a left orbital mass corresponding to an enlarged lacrimal gland shown by CT. The histologic features of the gland were consistent with the diagnosis, and with steroid treatment, the gland decreased in size. Although rare, the diagnosis of sinus histiocytosis with massive lymphadenopathy has to be considered in cases of lacrimal gland enlargement.
Azoulay
Robin
R
Department of Pediatric Radiology, Hôpital St-Vincent-de Paul, Institut Curie, 82 Avenue Denfert-Rochereau, 75674 Paris, France.
Brisse
Hervé
H
Fréneaux
Paul
P
Ferey
Solène
S
Kalifa
Gabriel
G
Adamsbaum
Catherine
C
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D001706:Biopsy; D002648:Child; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D015618:Histiocytosis, Sinus / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D006984:Hypertrophy / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D007765:Lacrimal Apparatus / Q000000981:diagnostic imaging* / Q000473:pathology; D007766:Lacrimal Apparatus Diseases / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D008297:Male; D012008:Recurrence; D014057:Tomography, X-Ray Computed
D000305:Adrenal Cortex Hormones