title: [Studies on crosslinkable coatings for biomedical application].
abstract: A novel crosslinkable coating for biomedical device was prepared by copolymerization of the constituent monomers via a free radical method. 1H-NMR and IR results indicated it had desirable structure. Surface characterization revealed that surface reorganization occurred in aqueous environment and a polyethylene oxied (PEO) enrichment surface was developed on coated surface. The in-vitro platelet-adhesion test and the plasma recalcification time(PRT) determination showed that the coated surface could resist the blood coagulation effectively.
authors.affiliation: Department of Polymer Science and Composite Materials, Zhejiang University, Hangzhou 310027, China. jianji@mail.hz.zj.cn
authors.forename: Jian
authors.initials: J
authors.lastname: Ji
authors.forename: Weidong
authors.initials: W
authors.lastname: Chen
authors.forename: Jianping
authors.initials: J
authors.lastname: Xu
authors.forename: Jiacong
authors.initials: J
authors.lastname: Shen
authors.forename: Dezeng
authors.initials: D
authors.lastname: Fang
authors.forename: Fuyu
authors.initials: F
authors.lastname: Sun
mesh_terms: D001777:Blood Coagulation; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D003432:Cross-Linking Reagents / Q000737:chemistry*; D008422:Materials Testing; D010973:Platelet Adhesiveness; D011092:Polyethylene Glycols / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D020099:Coated Materials, Biocompatible; D003432:Cross-Linking Reagents; D011092:Polyethylene Glycols