[Mass spectrum and uniformity of decomposition of certain 2-substituted 9-(o-chlorbenzyl)-8-azahypoxanthines].
The regularities of mass spectrometric fragmentation under electron impact of new 9-(o-chlorobenzyl)-8-azahypoxantines with (N-aryl)amidocarbonylmethylthiomethyl substituents in position 2 were studied. The main fragmentation pathways are the elimination of Ar-NH+ and o-chlorobenzyl ions and cleavage of C-S bonds, characteristic of organic sulfides. During the fragmentations, some rearrangements occur, consisting in the transfer of labile hydrogen atoms from the alpha-positions to ions being eliminated. Fragmentation of 8-azapurine parts of the molecules does not prevail. Peaks of molecular ions are clearly visible in the mass spectra of all the substances studied. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2004, vol. 30, no. 1; see also http://www.maik.ru.
Kuleshov
K V
KV
Mendeleev University of Chemical Technology, Miusskaya pl. 9, Moscow, 125047 Russia.
Adamov
A V
AV
Belokon'
A I
AI
Rodin
O G
OG
Perevalov
V P
VP
El'man
A R
AR
D019271:Hypoxanthine / Q000737:chemistry*; D013058:Mass Spectrometry / Q000379:methods*; D015394:Molecular Structure
D019271:Hypoxanthine