title: Surgical orthodontic correction of acromegaly with mandibular prognathism.
abstract: A male (30 years five months) who complained of mandibular prominence and masticatory dysfunction was diagnosed as a mandibular prognathic with acromegaly after cephalometric and endocrine examinations. The level of growth hormone (GH) subsequent to a transsphenoidal hypophysectomy had been controlled by medicines for about five years. Surgical orthodontic correction improved his occlusion and profile, but magnetic resonance imaging detected a recurrent adenoma in the cranial base during the retention period. The recurrence resulted in slight prognathic changes of the patient with a high level of GH. This is a case report of the treatment of an acromegalic patient discussing growth considerations that could influence the orthodontic treatment plan and long-term stability.
authors.affiliation: Department of Orthodontics, Graduate School of Dentistry, Osaka University, Osaka, Japan. tyagi@dent.osaka-u.ac.jp
authors.forename: Takakaza
authors.initials: T
authors.lastname: Yagi
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Kawakami
authors.forename: Kenji
authors.initials: K
authors.lastname: Takada
mesh_terms: D000172:Acromegaly / Q000601:surgery*; D000236:Adenoma / Q000175:diagnosis / Q000601:surgery; D000328:Adult; D005500:Follow-Up Studies; D006801:Humans; D007016:Hypophysectomy; D008279:Magnetic Resonance Imaging; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D009971:Orthodontics, Corrective; D010911:Pituitary Neoplasms / Q000601:surgery; D011378:Prognathism / Q000601:surgery*; D012888:Skull Neoplasms / Q000175:diagnosis; D016896:Treatment Outcome