title: Role of CO(2) pneumoperitoneum-induced acidosis in CO(2) pneumoperitoneum-enhanced adhesion formation in mice.
abstract: The effect of assisted ventilation and CO(2) pneumoperitoneum during laparoscopic surgery upon blood gases and adhesion formation were evaluated in mice. We confirmed that the CO(2) pneumoperitoneum induces acidosis and enhances adhesion formation, and an association between both effects was demonstrated, together with its modulation by the assisted ventilation.
authors.forename: Carlos Roger
authors.initials: CR
authors.lastname: Molinas
authors.forename: Marc
authors.initials: M
authors.lastname: Tjwa
authors.forename: Bernard
authors.initials: B
authors.lastname: Vanacker
authors.forename: Maria Mercedes
authors.initials: MM
authors.lastname: Binda
authors.forename: Osama
authors.initials: O
authors.lastname: Elkelani
authors.forename: Philippe Robert
authors.initials: PR
authors.lastname: Koninckx
mesh_terms: D000138:Acidosis / Q000139:chemically induced* / Q000150:complications*; D000818:Animals; D002245:Carbon Dioxide / Q000009:adverse effects*; D005260:Female; D051379:Mice; D011027:Pneumoperitoneum; D000267:Tissue Adhesions / Q000209:etiology*
chemical_list: D002245:Carbon Dioxide