title: Betuligenol derivative with growth inhibition and antifeedant activity.
abstract: The title chiral amine, 3-(4-methoxyphenyl)-1-methylpropylamine 5 has been synthesized from naturally abundant betuligenol 1 in three steps and also in good yield. Furthermore, the versatile intermediate 3 could be manipulated for the preparation of chiral disulphide 7. The amine derivative 5 prepared from (-)-betuligenol showed significant growth inhibition and antifeedant activity.
authors.affiliation: Central Institute of Medicinal and Aromatic Plants, PO CIMAP, Lucknow-226 015, India. sk.chattopadhyay@cimap.res.in
authors.forename: Sunil K
authors.initials: SK
authors.lastname: Chattopadhyay
authors.forename: Sachin
authors.initials: S
authors.lastname: Srivastava
authors.forename: Koneni V
authors.initials: KV
authors.lastname: Sashidhara
authors.forename: Arun K
authors.initials: AK
authors.lastname: Tripathi
authors.forename: Asish K
authors.initials: AK
authors.lastname: Bhattacharya
authors.forename: Arvind S
authors.initials: AS
authors.lastname: Negi
mesh_terms: D000818:Animals; D002074:Butanones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D005247:Feeding Behavior / Q000187:drug effects* / Q000502:physiology; D006131:Growth Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D007313:Insecta; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018515:Plant Leaves; D020946:Taxus
chemical_list: D002074:Butanones; D006131:Growth Inhibitors; D010936:Plant Extracts; C035522:raspberry ketone