title: Influenza A virus-associated acute necrotizing encephalopathy in the United States.
abstract: During the past several years, influenza-associated acute necrotizing encephalopathy has been well-recognized in Asia but has not yet been reported in the United States. We describe a 28-month-old patient who displayed the classical clinical features of acute necrotizing encephalopathy in association with a documented influenza A infection. This disease is characterized by fever, a rapid alteration in consciousness and seizures, with radiologic involvement of the bilateral thalami and cerebellum.
authors.affiliation: Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232-2581, USA.
authors.forename: Joern-Hendrik
authors.initials: JH
authors.lastname: Weitkamp
authors.forename: Michelle Donna
authors.initials: MD
authors.lastname: Spring
authors.forename: Terrance
authors.initials: T
authors.lastname: Brogan
authors.forename: Harold
authors.initials: H
authors.lastname: Moses
authors.forename: Karen C
authors.initials: KC
authors.lastname: Bloch
authors.forename: Peter Farnum
authors.initials: PF
authors.lastname: Wright
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001927:Brain Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000821:virology*; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009980:Influenza A virus; D007251:Influenza, Human / Q000150:complications* / Q000453:epidemiology; D014481:United States / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents