Topical vitamin D analogs.
Calcipotriene offers a safe and effective option in the treatment of plaque psoriasis. It helps regulate the abnormal growth and production of keratinocytes, as well as has a number of effects on inflammation seen with psoriasis. When used as monotherapy or in combination with corticosteroids, it may help reduce the adverse effects seen with chronic steroid use. Calcipotriene is currently only indicated for plaque psoriasis; however, it has shown promise for use in a wide range of dermatologic conditions.
Kieffer
Michael A
MA
D000279:Administration, Cutaneous; D002117:Calcitriol / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D015603:Keratinocytes / Q000187:drug effects / Q000502:physiology; D008010:Lichen Planus / Q000188:drug therapy; D009824:Ointments; D010353:Patient Education as Topic; D018579:Patient Selection; D011565:Psoriasis / Q000188:drug therapy*; D012594:Scleroderma, Localized / Q000188:drug therapy; D014481:United States; D014486:United States Food and Drug Administration; D014807:Vitamin D / Q000031:analogs & derivatives*; D014820:Vitiligo / Q000188:drug therapy
D003879:Dermatologic Agents; D009824:Ointments; D014807:Vitamin D; C055085:calcipotriene; D002117:Calcitriol