title: Epstein-Barr virus-associated smooth muscle tumor of the basal ganglia in an HIV+ child: case report and review of the literature.
abstract: We describe the clinicopathologic features of an Epstein-Barr virus (EBV)-associated smooth muscle tumor arising in the basal ganglia of a 10-year-old human immunodeficiency virus (HIV)-positive child. Only a few cases of intracranial smooth muscle tumors are reported in the literature and virtually all of these have been extra-axial, involving the dura or sinuses in HIV+ adults. Our case underscores the need to include an EBV-associated smooth muscle tumor in the differential diagnosis when evaluating intracranial mass lesions in immunodeficient children.
authors.affiliation: Department of Anatomic Pathology, Suite 1620, Children's National Medical Center, 111 Michigan Avenue N.W., Washington, DC 20010, USA. skumar@cnmc.org
authors.forename: Shimareet
authors.initials: S
authors.lastname: Kumar
authors.forename: Mariarita
authors.initials: M
authors.lastname: Santi
authors.forename: Gilbert
authors.initials: G
authors.lastname: Vezina
authors.forename: Tena
authors.initials: T
authors.lastname: Rosser
authors.forename: Roma S
authors.initials: RS
authors.lastname: Chandra
authors.forename: Robert
authors.initials: R
authors.lastname: Keating
mesh_terms: D001479:Basal Ganglia / Q000473:pathology* / Q000821:virology; D001932:Brain Neoplasms / Q000473:pathology* / Q000821:virology; D002648:Child; D003937:Diagnosis, Differential; D020031:Epstein-Barr Virus Infections / Q000276:immunology*; D015658:HIV Infections / Q000150:complications*; D004854:Herpesvirus 4, Human; D006801:Humans; D016867:Immunocompromised Host; D008279:Magnetic Resonance Imaging; D008297:Male; D018235:Smooth Muscle Tumor / Q000473:pathology* / Q000821:virology