Charcot-Marie-Tooth disease: extensive cranial nerve involvement on CT and MR imaging.
We report a case of genetically verified Charcot-Marie-Tooth disease in which the patient had cranial nerve symptoms. CT and MR imaging demonstrated enlargement of several cranial nerves, as well as their skull-base foramina, with faint contrast material enhancement identified.
Aho
Todd R
TR
Section of Neuroradiology, St. Joseph's Hospital and Medical Center, Barrow Neurologic Institute, 350 W. Thomas Road, Phoenix, AZ 85013, USA.
Wallace
Robert C
RC
Pitt
Alan M
AM
Sivakumar
Kumaraswamy
K
D002607:Charcot-Marie-Tooth Disease / Q000175:diagnosis* / Q000235:genetics; D002872:Chromosome Deletion; D003056:Cochlear Nerve / Q000473:pathology; D003389:Cranial Nerve Diseases / Q000175:diagnosis* / Q000235:genetics*; D003638:Deafness / Q000175:diagnosis / Q000235:genetics; D005154:Facial Nerve / Q000473:pathology; D006801:Humans; D006984:Hypertrophy; D008279:Magnetic Resonance Imaging; D008297:Male; D008416:Mastoid / Q000473:pathology; D008565:Membrane Proteins / Q000235:genetics; D008875:Middle Aged; D010375:Pedigree; D014057:Tomography, X-Ray Computed; D014276:Trigeminal Nerve / Q000473:pathology; D014277:Trigeminal Neuralgia / Q000175:diagnosis / Q000235:genetics
D008565:Membrane Proteins; C489785:PXMP2 protein, human