Combined occurrence of von Willebrand's disease and factor XIII deficiency: a case report.
We report the case of a three year old female child with combined occurrence of von Willebrand's disease and factor XIII deficiency, an extremely rare combination. The patient presented with prolonged bleeding following cuts and wounds. Clot solubility test using 5M urea was positive. Platelet aggregation using ristocetin was reduced, which corrected on adding normal plasma. Aggregation with other agonists was normal. We discuss the clinico- hematological profile of the case. Only one such case has been reported in literature in the past to the best of our knowledge.
Batra
Vineeta Vijay
VV
Department of Hematology, All India Institute of Medical Sciences, New Delhi. vvbatraa@2rediffmail.com
Saxena
Renu
R
Sharma
Lalit Mohan
LM
Kashyap
Rajesh
R
Chaudhry
Ved Prakash
VP
D002675:Child, Preschool; D005177:Factor XIII Deficiency / Q000097:blood / Q000150:complications*; D005260:Female; D006801:Humans; D010641:Phenotype; D014842:von Willebrand Diseases / Q000097:blood / Q000150:complications*