Dissemination of a clone of unusual phenotype of pandrug-resistant Acinetobacter baumannii at a university hospital in Taiwan.
From December 2002 to February 2003, 15 isolates of pandrug-resistant unidentified Acinetobacter species were recovered from seven patients treated on different wards or intensive care units. Both 16S-23S rRNA intergenic spacer PCR-restriction fragment length polymorphism profiles and sequence analysis of these isolates identified them as Acinetobacter baumannii. This pandrug-resistant A. baumannii strain with an unusual phenotype could persist in humans for long periods and was widely disseminated throughout the hospital.
Kuo
Lu-Cheng
LC
Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
Teng
Lee-Jene
LJ
Yu
Chong-Jen
CJ
Ho
Shen-Wu
SW
Hsueh
Po-Ren
PR
D000151:Acinetobacter Infections / Q000382:microbiology / Q000635:transmission*; D040981:Acinetobacter baumannii / Q000145:classification / Q000187:drug effects / Q000235:genetics*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003428:Cross Infection / Q000382:microbiology / Q000635:transmission*; D021903:DNA, Ribosomal Spacer; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D005260:Female; D006785:Hospitals, University; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012338:RNA, Ribosomal, 23S / Q000235:genetics; D017422:Sequence Analysis, DNA; D013624:Taiwan / Q000453:epidemiology
D021903:DNA, Ribosomal Spacer; D012336:RNA, Ribosomal, 16S; D012338:RNA, Ribosomal, 23S