[Clinical-parasitological response to treatment with quinine associated to doxycycline in uncomplicated falciparum malaria].
The response of patients with uncomplicated falciparum malaria to quinine plus doxycycline was studied in an open clinical trial. The majority (76.2%; n = 16) had plasmodia sensitive to the treatment and 23.8% (n = 5) were resistant. This therapeutic scheme appears to be a good option in uncomplicated falciparum malaria.
Leal
Osvaldo
O
Hospital Dr. Manoel Marinho Monte (Plácido de Castro, AC) da Secretaria de Estado de Saúde do Acre, Rio Branco, AC. ms.osvaldo@ac.gov.br
Leal
Elaine Azevedo Soares
EA
Borges Júnior
Franklin Roberto Pereira
FR
Paez
Maria Luiza Torres
ML
Teodósio
Sebastião
S
Tavares-Neto
José
J
D000293:Adolescent; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D002648:Child; D004318:Doxycycline / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D016778:Malaria, Falciparum / Q000188:drug therapy*; D010963:Plasmodium falciparum / Q000187:drug effects; D011803:Quinine / Q000627:therapeutic use*; D016896:Treatment Outcome
D000962:Antimalarials; D011803:Quinine; D004318:Doxycycline