Sulfamethoxazole-imprinted polymer for selective determination of sulfamethoxazole in tablets.
A sulfamethoxazole (SMO)-imprinted polymer (MIP) was prepared in acetonitrile using the mixture of acrylamide and 4-vinylpyridine as functional monomers. The molecular recognition properties of the polymer was evaluated in both acetonitrile and aqueous acetonitrile mobile phases. SMO contents in two kinds of tablets were determined satisfactorily using the MIP packed HPLC column with aqueous mobile phase.
Zheng
Ning
N
Laboratory Bioorganic & Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University Beijing 100871, China.
Li
Yuan-Zong
YZ
Wen
Mei-Juan
MJ
D000890:Anti-Infective Agents / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D011108:Polymers / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D013420:Sulfamethoxazole / Q000032:analysis* / Q000737:chemistry*; D013607:Tablets / Q000737:chemistry*
D000890:Anti-Infective Agents; D011108:Polymers; D013607:Tablets; D013420:Sulfamethoxazole