title: The effect of duodenogastric reflux on Helicobacter pylori presence and gastric histopathologic changes.
abstract: OBJECTIVE
  In this study, we investigated the presence of Helicobacter pylori infection and gastric histological changes in unoperated patients with and without duodenogastric reflux.
  
  
  METHODS
  Twenty-two women and 15 men, mean age of 51.17 years, who had duodenogastric reflux during endoscopy were included. Thirty-seven age-and gender-matched patients without duodenogastric reflux served as controls. The Helicobacter pylori infection was detected by histology. The Helicobacter pylori density and gastric histology according to the modified Sydney system were evaluated with specimens from antrum, corpus and fundus.
  
  
  RESULTS
  The presence of Helicobacter pylori, Helicobacter pylori density, chronic inflammation score, lymphoid follicles, atrophy, and intestinal metaplasia were similar in patients with and without duodenogastric reflux (p>0.05). Acute inflammation was found to be lower in the antrum (p<0.05) in the duodenogastric reflux-positive group.
  
  
  CONCLUSIONS
  Duodenogastric reflux does not affect the presence of Helicobacter pylori and gastric histopathologic changes.
authors.affiliation: Antalya State Hospital, Department of Gastroenterology, Antalya, Turkey. vildant2000@yahoo.com
authors.forename: Vildan
authors.initials: V
authors.lastname: Taşkin
authors.forename: Murat
authors.initials: M
authors.lastname: Sedele
authors.forename: Osman
authors.initials: O
authors.lastname: Saka
authors.forename: Bülent
authors.initials: B
authors.lastname: Kantarçeken
mesh_terms: D001284:Atrophy; D016022:Case-Control Studies; D004383:Duodenogastric Reflux / Q000150:complications* / Q000175:diagnosis / Q000473:pathology*; D016145:Endoscopy, Digestive System; D005260:Female; D005756:Gastritis / Q000382:microbiology* / Q000473:pathology; D016481:Helicobacter Infections / Q000382:microbiology* / Q000473:pathology; D016480:Helicobacter pylori; D006801:Humans; D007249:Inflammation; D008297:Male; D008679:Metaplasia; D008875:Middle Aged; D012720:Severity of Illness Index; D013270:Stomach / Q000473:pathology*