2-O-(beta-D-Glucopyranosyl)ascorbic acid, a novel ascorbic acid analogue isolated from Lycium fruit.
A novel stable precursor of ascorbic acid (vitamin C), 2-O-(beta-D-glucopyranosyl)ascorbic acid, was isolated from both the ripe fresh fruit and dried fruit of Lycium barbarum L., a plant of the Solanaceae family. The chemical structure was inferred by instrumental analyses and confirmed by chemical synthesis. The dried fruit of Lycium barbarum L. contained ca. 0.5% of it, which is comparable to the ascorbic acid content of fresh lemons. It increased the blood ascorbic acid by oral administration to rats, and it was also detected in blood from the portal vein.
Toyoda-Ono
Yoshiko
Y
Health Care Science Laboratory, Institute for Food & Beverage, Technological Development Center, Suntory Ltd., 5-2-5, Yamazaki, Shimamoto-cho, Mishima-gun, Osaka 618-0001, Japan.
Maeda
Mitsuru
M
Nakao
Masahiro
M
Yoshimura
Makiko
M
Sugiura-Tomimori
Namino
N
Fukami
Harukazu
H
D000818:Animals; D001205:Ascorbic Acid / Q000031:analogs & derivatives / Q000097:blood / Q000302:isolation & purification* / Q000493:pharmacokinetics; D002851:Chromatography, High Pressure Liquid; D005638:Fruit / Q000737:chemistry*; D007408:Intestinal Absorption; D032305:Lycium / Q000737:chemistry*; D015394:Molecular Structure; D051381:Rats
C484753:2-O-(beta-D-glucopyranosyl)ascorbic acid; D001205:Ascorbic Acid