title: [Renal and tissue fibrinolysis dysfunction in secondary pyelonephritis in children before and after the surgery].
abstract: Indexes of fibrinolytic and proteolytic blood and urine activity in secondary pyelonephritis in children up to and after operative treatment for obstructive pyelonephritis were studied. The simulating method of hydronephrosis and secondary pyelonephritis was elaborated, changes of the tissues fibrinolytic activity of pyelourethral segment region in conditions of experiment and in operated children were studied. After the operation the conditions for urodynamics disorder occurrence are creating, in particular, lowering of activity of urine urokinase, disorder of tissues enzymatic fibrinolysis of pyelourethral segment with activation of general hemocoagulative potential, what promotes the urolythic disease and hydronephrosis occurrence and necessity for according correction.
authors.forename: B M
authors.initials: BM
authors.lastname: Bodnar
authors.forename: A V
authors.initials: AV
authors.lastname: Irynchyn
authors.forename: V L
authors.initials: VL
authors.lastname: Brozhyk
authors.forename: H B
authors.initials: HB
authors.lastname: Bodnar
authors.forename: O I
authors.initials: OI
authors.lastname: Khomko
mesh_terms: D000818:Animals; D002648:Child; D004285:Dogs; D005342:Fibrinolysis / Q000502:physiology*; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis* / Q000503:physiopathology*; D010447:Peptide Hydrolases / Q000097:blood / Q000652:urine; D011182:Postoperative Care; D011184:Postoperative Period; D011300:Preoperative Care; D011704:Pyelonephritis / Q000503:physiopathology* / Q000601:surgery*; D014522:Urethral Diseases / Q000503:physiopathology*; D014568:Urokinase-Type Plasminogen Activator / Q000652:urine
chemical_list: D010447:Peptide Hydrolases; D014568:Urokinase-Type Plasminogen Activator