Respiratory syncytial virus-related pneumonia after stem cell transplantation successfully treated with palivizumab and steroid therapy.
A case is reported of a 56-y-old woman with a second relapse of Hodgkin's disease who early developed after autologous stem cell transplantation (ASCT) a severe RSV-related interstitial pneumonia successfully treated with 1-d intravenous palivizumab 8 mg/kg plus low-dose systemic steroid therapy. B-cells suppression with CMV antigenaemia were then observed and required treatment with ganciclovir and liposomal amfotericine B.
Banna
Giuseppe Luigi
GL
Medical Oncology, University Hospital of Padova, Padova, Italy. gbanna@yahoo.com
Aversa
Savina Maria Luciana
SM
Cattelan
Anna Maria
AM
Crivellari
Gino
G
Monfardini
Silvio
S
D000284:Administration, Oral; D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D061067:Antibodies, Monoclonal, Humanized; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006689:Hodgkin Disease / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007262:Infusions, Intravenous; D008875:Middle Aged; D000069455:Palivizumab; D011024:Pneumonia, Viral / Q000188:drug therapy* / Q000821:virology; D012008:Recurrence; D018357:Respiratory Syncytial Virus Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology*; D012720:Severity of Illness Index; D033581:Stem Cell Transplantation / Q000009:adverse effects* / Q000379:methods; D013256:Steroids / Q000008:administration & dosage*; D016896:Treatment Outcome
D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D013256:Steroids; D000069455:Palivizumab