title: Crohn's-associated chronic recurrent multifocal osteomyelitis responsive to infliximab.
abstract: We report a case of chronic recurrent clavicular osteomyelitis in association with Crohn disease. Steroid therapy resulted in partial remission; however, intractable shoulder pain and an enlarging clavicular mass subsequently recurred. Infliximab therapy resulted in significant improvement in the degree of bone pain and resolution of the large sclerotic clavicular lesion.
authors.affiliation: Inflammatory Bowel Disease Program, Section of Gastroenterology, The Children's Mercy Hospital and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA.
authors.forename: Ellen
authors.initials: E
authors.lastname: Carpenter
authors.forename: Mary Anne
authors.initials: MA
authors.lastname: Jackson
authors.forename: Craig A
authors.initials: CA
authors.lastname: Friesen
authors.forename: Marc
authors.initials: M
authors.lastname: Scarbrough
authors.forename: Charles C
authors.initials: CC
authors.lastname: Roberts
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D002648:Child; D002908:Chronic Disease; D002968:Clavicle; D003424:Crohn Disease / Q000150:complications / Q000188:drug therapy*; D005260:Female; D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D006801:Humans; D000069285:Infliximab; D010019:Osteomyelitis / Q000150:complications / Q000188:drug therapy*; D010146:Pain / Q000188:drug therapy / Q000209:etiology
chemical_list: D000911:Antibodies, Monoclonal; D005765:Gastrointestinal Agents; D000069285:Infliximab