title: Bioactivation and resistance to mitomycin C.
authors.affiliation: Department of Pharmacology and Developmental Therapeutics Program, Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
authors.forename: Helen A
authors.initials: HA
authors.lastname: Seow
authors.forename: Philip G
authors.initials: PG
authors.lastname: Penketh
authors.forename: Raymond P
authors.initials: RP
authors.lastname: Baumann
authors.forename: Alan C
authors.initials: AC
authors.lastname: Sartorelli
mesh_terms: D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000378:metabolism; D001711:Biotransformation; D019008:Drug Resistance, Neoplasm; D006801:Humans; D016685:Mitomycin / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism
chemical_list: D000903:Antibiotics, Antineoplastic; D001426:Bacterial Proteins; D016685:Mitomycin; D010088:Oxidoreductases; C088145:mcrA protein, Streptomyces lavendulae