[Spatio-temporal changes in the metabolic processes in the blood-tissue system in the terminal states of the organism].
The role of synergism in diffusion of oxygen from erythrocyte into interstitial liquid and water filtration through the capillary wall was studied on the model using the following parameters: hydrostatic pressure on arterial and venous ends of the capillary (Pa and Pb), oncotic blood and tissue pressure (Pob and Pot), pore radius in the capillary (r), the number of pores in the capillary (n) per m2, amount of the liquid released from the capillary (q(x)), gas diffusion coefficient (D), time of erythrocyte movement in the capillary (T), speed of oxygen consumption (V), maximal distance with adequate V (Xmax), characteristic time of diffusion (Topt). It is shown that diffuse and convective components of the metabolic process have their own contribution and in changed conditions they redistribute. In increased number and diameter of hydravlic pores the greatest role in tissue saturation with oxygen belongs to convective metabolism, but in this situation tissues contain areas lacking oxygen.
Kozlova
E K
EK
Fomina
U A
UA
Moroz
V V
VV
Bogushevich
M S
MS
Chernysh
A M
AM
D002196:Capillaries / Q000378:metabolism / Q000502:physiology*; D004058:Diffusion; D045604:Extracellular Fluid / Q000502:physiology; D005374:Filtration; D006801:Humans; D008954:Models, Biological; D010100:Oxygen / Q000378:metabolism*; D019452:Terminally Ill
D010100:Oxygen