title: Myeloma with predominant phalangeal involvement.
abstract: A case of plasma cell myeloma involving the middle phalanx of the ring finger is reported. This was a case of a non-secretory myeloma; however, monoclonal immunoglobulins were demonstrated by immunohistochemical studies. Plasma cell myeloma with phalangeal involvement is extremely rare: our literature search disclosed only two well-documented cases. Plasma cell myeloma may occur in the hand, so it should be considered in the pre-biopsy differential diagnosis when bone lesions radiologically consistent with myeloma are encountered.
authors.affiliation: Department of Orthopaedic Surgery, Letterkenny General Hospital, Ireland. nabeel@esatclear.ie
authors.forename: Nabeel
authors.initials: N
authors.lastname: Dastgir
authors.forename: Gerry
authors.initials: G
authors.lastname: O'Dowd
authors.forename: Peter
authors.initials: P
authors.lastname: O'Rourke
mesh_terms: D001707:Biopsy, Needle; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008662:Metacarpophalangeal Joint / Q000000981:diagnostic imaging* / Q000473:pathology*; D008875:Middle Aged; D009101:Multiple Myeloma / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology*; D011859:Radiography; D035583:Rare Diseases; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine