title: The cell equator - more than poles apart.
abstract: Cytokinesis is the last ritual of a dividing cell. Determining the position and horizon of the cell furrow is important for equal distribution of cytoplasmic content between the two daughter cells. The traditional view promotes a classical sequence of bipolar spindle formation followed by cytokinesis. However, a new understanding has recently emerged that uncouples these events. The cell-furrow formation seems to ignore spindle polarity and is instead dependent on the stability and dynamics of cortical microtubules.
authors.affiliation: Systems Biology Group, Bioinformatics Institute, Matrix, 138671, Singapore. pk@bii-sg.org
authors.forename: Pawan
authors.initials: P
authors.lastname: Dhar
mesh_terms: D000705:Anaphase / Q000187:drug effects / Q000502:physiology; D000818:Animals; D000906:Antibodies / Q000494:pharmacology; D002352:Carrier Proteins / Q000276:immunology; D018797:Cell Cycle Proteins; D002460:Cell Line; D048750:Cell Nucleus Division / Q000502:physiology; D018385:Centrosome / Q000187:drug effects / Q000502:physiology; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism; D048749:Cytokinesis / Q000187:drug effects / Q000502:physiology*; D007734:Kymography; D008394:Marsupialia; D008870:Microtubules / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D009687:Nuclear Proteins; D011743:Pyrimidines / Q000494:pharmacology; D008941:Spindle Apparatus / Q000187:drug effects / Q000502:physiology*; D014404:Tubulin / Q000187:drug effects / Q000378:metabolism
chemical_list: D000906:Antibodies; D002352:Carrier Proteins; D018797:Cell Cycle Proteins; D002868:Chromosomal Proteins, Non-Histone; D009687:Nuclear Proteins; D011743:Pyrimidines; D014404:Tubulin