Dynamics of brain activity in motor and frontal cortical areas during music listening: a magnetoencephalographic study.
There are formidable problems in studying how 'real' music engages the brain over wide ranges of temporal scales extending from milliseconds to a lifetime. In this work, we recorded the magnetoencephalographic signal while subjects listened to music as it unfolded over long periods of time (seconds), and we developed and applied methods to correlate the time course of the regional brain activations with the dynamic aspects of the musical sound. We showed that frontal areas generally respond with slow time constants to the music, reflecting their more integrative mode; motor-related areas showed transient-mode responses to fine temporal scale structures of the sound. The study combined novel analysis techniques designed to capture and quantify fine temporal sequencing from the authentic musical piece (characterized by a clearly defined rhythm and melodic structure) with the extraction of relevant features from the dynamics of the regional brain activations. The results demonstrated that activity in motor-related structures, specifically in lateral premotor areas, supplementary motor areas, and somatomotor areas, correlated with measures of rhythmicity derived from the music. These correlations showed distinct laterality depending on how the musical performance deviated from the strict tempo of the music score, that is, depending on the musical expression.
Popescu
Mihai
M
Laboratory for Human Brain Dynamics, Brain Science Institute, RIKEN, Wako, Saitama 351-0198, Japan.
Otsuka
Asuka
A
Ioannides
Andreas A
AA
D000328:Adult; D000465:Algorithms; D001143:Arousal / Q000502:physiology; D001288:Attention / Q000502:physiology; D001303:Auditory Cortex / Q000502:physiology; D001307:Auditory Perception / Q000502:physiology*; D001931:Brain Mapping; D002531:Cerebellum / Q000502:physiology; D004292:Dominance, Cerebral / Q000502:physiology; D005583:Fourier Analysis; D005625:Frontal Lobe / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D015225:Magnetoencephalography; D008297:Male; D009044:Motor Cortex / Q000502:physiology*; D009146:Music; D009415:Nerve Net / Q000502:physiology; D009434:Neural Pathways / Q000502:physiology; D009474:Neurons / Q000502:physiology; D010898:Pitch Perception / Q000502:physiology; D017397:Prefrontal Cortex / Q000502:physiology; D013003:Somatosensory Cortex / Q000502:physiology; D013018:Sound Spectrography; D013223:Statistics as Topic; D013702:Temporal Lobe / Q000502:physiology; D013998:Time Perception / Q000502:physiology