Multiple lymphomatous polyposis of the colon originating from T-cells: a case report.
Multiple lymphomatous polyposis is an unusual form of non-Hodgkin's lymphoma characterised by myriad polyps throughout the alimentary tract. Most multiple lymphomatous polyposis cases are derived from B-cell, and there has been little information on multiple lymphomatous polyposis of T-cell origin. A 67-year-old Japanese man presented with lower abdominal pain and diarrhoea of 4-week duration. Colonoscopy revealed numerous small umbilicated polyps and several raised erosions in the colorectum. Biopsy specimens showed diffuse proliferation of lymphoma cells negative for B-cell markers but positive for T-cell markers. Polymerase chain reaction using extracted chromosomal deoxyribonucleic acid from paraffin-embedded samples identified T-cell receptor gamma and delta gene recombination. The patient was treated with combined chemotherapy, leading to complete resolution of the lesions.
Isomoto
H
H
Department of Endoscopy, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki 852-8102, Japan. hajimei2002@yahoo.co.jp
Maeda
T
T
Akashi
T
T
Tsuchiya
T
T
Kawaguchi
Y
Y
Sawayama
Y
Y
Koida
S
S
Ohnita
K
K
Kohno
S
S
Tomonaga
M
M
D000368:Aged; D003111:Colonic Polyps / Q000473:pathology*; D015179:Colorectal Neoplasms / Q000473:pathology*; D006801:Humans; D016399:Lymphoma, T-Cell / Q000473:pathology*; D008297:Male; D013601:T-Lymphocytes / Q000473:pathology