[Bcl-2 apoptosis regulating proteins in mouse tissues after exposure to 20 cGy of gamma-radiation].
A pronounced increase of Bcl-2 content was observed in thymus of mice exposed to 20 cGy of gamma-radiation 1 and 24 hours after the exposure; six days after the exposure the bcl-2 content lowered to the control one. No changes in bcl-2 level were revealed in mice liver during the period of observation. A level of Bax protein was stable in mice thymus during 60 days of observation.
Pushkareva
N B
NB
State Research Center-Institute of Biphysics, Ministry of Public Health of Russian Federation, Moscow, 123182 Russia.
Sorokina
N I
NI
Koterov
A N
AN
Nikol'skiĭ
A V
AV
Filippovich
I V
IV
D000818:Animals; D017209:Apoptosis / Q000528:radiation effects*; D005720:Gamma Rays; D015151:Immunoblotting; D008099:Liver / Q000378:metabolism / Q000528:radiation effects*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011518:Proto-Oncogene Proteins / Q000032:analysis / Q000378:metabolism; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000032:analysis* / Q000378:metabolism; D011829:Radiation Dosage; D011839:Radiation, Ionizing; D013950:Thymus Gland / Q000378:metabolism / Q000528:radiation effects*; D013997:Time Factors; D051028:bcl-2-Associated X Protein
C494827:Bax protein, mouse; D011518:Proto-Oncogene Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D051028:bcl-2-Associated X Protein