[Coronary stenting in patients with acute coronary syndrome and renal dysfunction].
OBJECTIVE
To evaluate the immediate and mid-term efficacy of coronary stenting in patients with acute coronary syndrome (ACS) and renal dysfunction.


METHODS
Sixty-three ACS patients with renal dysfunction were included (RD group) and 63 contemporaneous ACS patients with normal renal function served as a control group. The clinical characteristics, stenting procedure and follow-up information were compared between the two groups.


RESULTS
Patients in the RD group had higher basic serum creatinine levels [(177 +/- 31) micro mol/L vs (98 +/- 21) micro mol/L, P < 0.001], lower left ventricular ejection fraction (0.45 +/- 0.10 vs 0.50 +/- 0.09, P < 0.05) and increased prevalence of multivessel coronary artery disease (84% vs 65%, P < 0.05) as well as > 50% renal artery stenosis (27% vs 8%, P < 0.05). There was no statistical difference in procedural success rate and major adverse cardiac events occurrence during a mean follow up time of 27 months (13% vs 8%, P = 0.38). In the RD group, the mean level of serum creatinine was significantly decreased [(177 +/- 31) micro mol/L vs (147 +/- 11) micro mol/L, P < 0.05] and 9 (69%) patients with renal artery stent implantation had normal creatinine levels during follow-up.


CONCLUSIONS
Coronary stenting is a safe and effective therapy for ACS patients complicated with renal dysfunction, two thirds of patients receiving renal stent implantation had normal serum creatinine during follow-up.
Zhang
Qi
Q
Department of Cardiology, Shanghai Ruijin Hospital, Shanghai 200025, China.
Shen
Wei-feng
WF
Zhang
Jian-sheng
JS
Zhang
Rui-yan
RY
Hu
Jian
J
Zhang
Xian
X
D000328:Adult; D000368:Aged; D017023:Coronary Angiography; D003327:Coronary Disease / Q000150:complications / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D051437:Renal Insufficiency / Q000628:therapy*; D015607:Stents