title: UniProt archive.
abstract: UniProt Archive (UniParc) is the most comprehensive, non-redundant protein sequence database available. Its protein sequences are retrieved from predominant, publicly accessible resources. All new and updated protein sequences are collected and loaded daily into UniParc for full coverage. To avoid redundancy, each unique sequence is stored only once with a stable protein identifier, which can be used later in UniParc to identify the same protein in all source databases. When proteins are loaded into the database, database cross-references are created to link them to the origins of the sequences. As a result, performing a sequence search against UniParc is equivalent to performing the same search against all databases cross-referenced by UniParc. UniParc contains only protein sequences and database cross-references; all other information must be retrieved from the source databases.
authors.affiliation: EMBL Outstation, The European Bioinformatics Institute (EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
authors.forename: Rasko
authors.initials: R
authors.lastname: Leinonen
authors.forename: Federico Garcia
authors.initials: FG
authors.lastname: Diez
authors.forename: David
authors.initials: D
authors.lastname: Binns
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Fleischmann
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Lopez
authors.forename: Rolf
authors.initials: R
authors.lastname: Apweiler
mesh_terms: D000595:Amino Acid Sequence; D003195:Computer Communication Networks; D003628:Database Management Systems; D030562:Databases, Protein; D004282:Documentation / Q000379:methods*; D033181:Information Dissemination / Q000379:methods; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet; D008969:Molecular Sequence Data; D011506:Proteins / Q000737:chemistry* / Q000145:classification; D020539:Sequence Analysis, Protein / Q000379:methods*; D018511:Systems Integration
chemical_list: D011506:Proteins