Problems in identification of Francisella philomiragia associated with fatal bacteremia in a patient with chronic granulomatous disease.
Francisella philomiragia is a rare gram-negative, halophilic coccobacillus with bizarre spherical forms on primary isolation. A case of F. philomiragia bacteremia in a 24-year-old patient with chronic granulomatous disease is reported. Identification of F. philomiragia was problematic with conventional tests but was done correctly and rapidly by kit 16S ribosomal DNA sequencing.
Friis-Møller
A
A
Department of Clinical Microbiology, Hvidovre Hospital, Denmark. alice.friis-moeller@hh.hosp.dk
Lemming
L E
LE
Valerius
N H
NH
Bruun
B
B
D000328:Adult; D016470:Bacteremia / Q000382:microbiology*; D015373:Bacterial Typing Techniques; D001483:Base Sequence; D004275:DNA, Ribosomal / Q000032:analysis; D017809:Fatal Outcome; D005603:Francisella / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology*; D006105:Granulomatous Disease, Chronic / Q000382:microbiology*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA
D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S