title: [The in vitro comparison of platelet induced ACC-M cell adhesion with and without Aspirin]
abstract: ObJECTIVE:Observation the affection of aspirin to adhesion of highly metastatic salivary adenoid cystic carcinoma(ACC-M) cell induced by platelet.METHODS:Adhesive ratios of ACC-M cell induced by platelet with or without aspirin were measured.RESULTS:After the addition of platelet rich plasma(PRP),adhesive ratio of ACC-M cell increased significantly (P<0.01). The treatment with aspirin after addition of PRP led to a nonsignificant increase of adhesive ratio (P>0.05).The reduction of adhesive ratio by aspirin was found dosage independent within concentration  range of 0.01-0.25g/L of aspirin. CONCLUSION:Adhesion of ACC-M cell was raised by added platelet.Addition of aspirin,platelet induced adhesion of ACC-M cell was inhibited significantly.
authors.affiliation: Department of Oral & Maxillofacial Surgery,School of Stomatology,Shanghai Second Medical University. Shanghai 200011,China.
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Gu
authors.forename: W L
authors.initials: WL
authors.lastname: Qiu
authors.forename: R G
authors.initials: RG
authors.lastname: He
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Zhang
authors.forename: X J
authors.initials: XJ
authors.lastname: Zhou