Antimicrobial susceptibility and mechanisms of resistance to quinolones and beta-lactams in Acinetobacter genospecies 3.
Antimicrobial susceptibility was determined in 15 epidemiologically unrelated clinical isolates of Acinetobacter genospecies 3. Moreover, the mechanisms of resistance to some beta-lactam antibiotics may be associated with the presence of a chromosomal cephalosporinase, AmpC, and the resistance to quinolones related to mutations in the gyrA and parC genes.
Ribera
A
A
Servei de Microbiologia, Institut Clínic Infeccions i Immunologia, IDIBAPS, Hospital Clínic, 08036 Barcelona, Spain.
Fernández-Cuenca
F
F
Beceiro
A
A
Bou
G
G
Martínez-Martínez
L
L
Pascual
A
A
Cisneros
J M
JM
Rodríguez-Baño
J
J
Pachón
J
J
Vila
J
J
D000150:Acinetobacter / Q000187:drug effects* / Q000235:genetics*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000494:pharmacology*; D005798:Genes, Bacterial / Q000235:genetics; D008826:Microbial Sensitivity Tests; D015363:Quinolones / Q000494:pharmacology*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D047090:beta-Lactams / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D015363:Quinolones; D047090:beta-Lactams