title: Synthesis of 4-hydroxy-7,8-dimethoxyisochroman-3-one and its plant growth-regulating properties on tobacco (Nicotiana tabacum cv. Petit Havana).
abstract: The synthesis of 6,7-dimethoxy-4-hydroxyisochroman-3-one 10 from 2,3-dimethoxytoluene (11) via glyoxylate 12 is reported. Compound 10 strongly inhibited vegetative growth of tobacco plants, whereas developmental patterns (protein levels, protein profile, pigments, and chlorophylls) were not affected. Morphological changes were observed in the leaves of the treated plants.
authors.affiliation: Instituto de Química Orgánica de Síntesis (CONICET-UNR), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, S2002LRK Rosario, República Argentina.
authors.forename: Darío A
authors.initials: DA
authors.lastname: Bianchi
authors.forename: Nicolás E
authors.initials: NE
authors.lastname: Blanco
authors.forename: Néstor
authors.initials: N
authors.lastname: Carrillo
authors.forename: Teodoro S
authors.initials: TS
authors.lastname: Kaufman
mesh_terms: D002839:Chromans / Q000138:chemical synthesis* / Q000494:pharmacology*; D010937:Plant Growth Regulators / Q000138:chemical synthesis* / Q000494:pharmacology*; D018515:Plant Leaves / Q000187:drug effects / Q000648:ultrastructure; D014026:Nicotiana / Q000187:drug effects* / Q000254:growth & development*
chemical_list: C484749:4-hydroxy-7,8-dimethoxyisochroman-3-one; D002839:Chromans; D010937:Plant Growth Regulators