title: System for the automated photothermal treatment of cutaneous vascular lesions.
abstract: It is well known that the use of tightly focused continuous wave lasers can be an effective treatment of common telangiactasia. In general, the technique requires the skills of a highly dexterous surgeon using the aid of optical magnification. Due to the nature of this approach, it has proven to be largely impractical. To overcome this, we have developed an automated system that alleviates the strain on the user associated with the manual tracing method. The device makes use of high contrast illumination, simple monochromatic imaging, and machine vision to determine the location of blood vessels in the area of interest. The vessel coordinates are then used as input to a two-dimensional laser scanner via a near real-time feedback loop to target, track, and treat. Such mechanization should result in increased overall treatment success, and decreased patient morbidity. Additionally, this approach enables the use of laser systems that are considerably smaller than those currently used, and consequently the potential for significant cost savings. Here we present an overview of a proof-of-principle system, and results using examples involving in vivo imaging of human skin.
authors.affiliation: Lumenis, Inc., 2400 Condensa Street, Santa Clara, California 95051, USA. dandersen@lumenis.com
authors.forename: Dan E
authors.initials: DE
authors.lastname: Andersen
authors.forename: Marek A
authors.initials: MA
authors.lastname: Niczyporuk
authors.forename: Michael W
authors.initials: MW
authors.lastname: Wiltberger
authors.forename: David G
authors.initials: DG
authors.lastname: Angeley
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D001331:Automation; D003199:Computer Systems; D004867:Equipment Design; D006801:Humans; D006979:Hyperthermia, Induced / Q000295:instrumentation; D053685:Laser Therapy; D007834:Lasers; D008962:Models, Theoretical; D010789:Phototherapy / Q000295:instrumentation; D012867:Skin / Q000098:blood supply*; D014652:Vascular Diseases / Q000175:diagnosis / Q000532:radiotherapy*