title: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and nuclear magnetic resonance analyses of end-functionalized saccharidic polymers: an example of a useful analytical technique combination.
abstract: The living cationic polymerization of a saccharidic monomer (1,2:3,4-di-O-isopropylidene-6-O-(2-vinyloxyethyl)-D-galactopyranose, GVE) gives rise to aldehyde end-capped polymers (PGVE--CHO) of low molar masses (<10 000 Da) and low molar mass distribution (<1.2). These polymers were derivatized by selective introduction of either hexamethylenediamine (PGVE-NH2) or 9-fluorenylmethyl carbazate (PGVE-Fmoc) end groups. The resulting polymers were fully characterized by complementary use of nuclear magnetic resonance (1H NMR) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS). The expected structure according to the polymerization mechanism, the occurrence of side reactions and the success of the post-functionalization reactions were confirmed.
authors.affiliation: LCPP CPE/CNRS 43 boulevard du 11 novembre 1918, Bat 308F, BP2077 69 616, Villeurbanne, France.
authors.forename: F
authors.initials: F
authors.lastname: D'Agosto
authors.forename: M T
authors.initials: MT
authors.lastname: Charreyre
authors.forename: C
authors.initials: C
authors.lastname: Pichot
authors.forename: G
authors.initials: G
authors.lastname: Dessalces
authors.forename: F
authors.initials: F
authors.lastname: Delolme
mesh_terms: D002623:Chemistry Techniques, Analytical / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D011134:Polysaccharides / Q000032:analysis*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*
chemical_list: D011134:Polysaccharides