title: [The diagnostic value of stress dobutamine echocardiography in stable coronary artery diseases].
abstract: The relation of stress dobutamine echocardiography test results to angiographic features was assessed in 551 patients with chest pain regarded as definite or probable stable angina pectoris. The indications for catheterization in each patient were determined at the discretion of the attending physician. All patients underwent diagnostic coronary angiography (clinically important coronary artery disease was defined as > 50 per cent narrowing of the diameter of at least one major vessel or > or = 50 per cent of the left main coronary artery) and stress dobutamine echocardiography (DSE): Ischemia was defined as new or worsening wall motion abnormalities using a 16-segment model. Sensitivity and specificity of DSE was calculated: 85% and 69% respectively for the entire group, 79% and 71% in women, 87% and 66% in men and compared with diagnostic value of the electrocardiographic exercise test (EE) in the same population. Sensitivity and specificity of the EE was respectively: 93% and 21% for the entire group, 91% and 16% in women, 94% and 27% in men.
  
  
  CONCLUSIONS
  1. DSE has comparable sensitivity but significantly higher specificity than EE. 2. Variables determining false positive result of DSE are as follows: mean maximal heart rate, reached % of the target heart rate and wall motion abnormalities present in single segment. 3. Variables determining false negative results are: sex (male) and one vessel disease. 4. Treatment with beta-adrenolytic agents increases incidence of nondiagnostic results of DSE.
authors.affiliation: Klinika Choroby Wieńcowej Instytutu Kardiologii w Warszawie.
authors.forename: Michał
authors.initials: M
authors.lastname: Lewandowski
authors.forename: Hanna
authors.initials: H
authors.lastname: Szwed
authors.forename: Ilona
authors.initials: I
authors.lastname: Kowalik
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Gasior
authors.forename: Andrzej
authors.initials: A
authors.lastname: Gackowski
authors.forename: Jarosław
authors.initials: J
authors.lastname: Kasprzak
authors.forename: Adam
authors.initials: A
authors.lastname: Spring
authors.forename: Edyta
authors.initials: E
authors.lastname: Płońska
authors.forename: Edmund
authors.initials: E
authors.lastname: Nartowicz
authors.forename: Andrzej
authors.initials: A
authors.lastname: Szyszka
authors.forename: Marek
authors.initials: M
authors.lastname: Michalski
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Krzymińska-Stasiuk
authors.forename: Jacek
authors.initials: J
authors.lastname: Górski
authors.forename: Krystyna
authors.initials: K
authors.lastname: Jaworska
authors.forename: Marianna
authors.initials: M
authors.lastname: Janion
authors.forename: Marek
authors.initials: M
authors.lastname: Demczuk
authors.forename: Andrzej
authors.initials: A
authors.lastname: Kleinrok
mesh_terms: D000787:Angina Pectoris / Q000000981:diagnostic imaging*; D017023:Coronary Angiography; D003937:Diagnosis, Differential; D025401:Echocardiography, Stress; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity