title: Use of autologous fibrin-platelet glue and bone fragments in maxillofacial surgery.
abstract: The use of autologous cryo-platelet gel and bone fragments in maxillofacial surgery is described. Cryo-platelet gel has been used successfully in 5 patients who underwent surgery for maxillary or mandibular problems. The level of improvement was scored, arbitrarily, from 0 to 4. Very favourable results were seen in our 5 patients. The glue preparation is very easy and inexpensive and the glue creates excellent and stable hemostasis. From a general point of view, we add additional anecdotal evidence supporting the utility of fibrin-platelet glue in terms of reduced infections and length of hospital stay, which suggest the need for well planned and controlled trials to show if there is benefit and when and this treatment modality should be used in maxillofacial surgery.
authors.affiliation: Department of Immunohematology and Blood Transfusion, San Martino University Hospital, Largo Rosanna Benzi 10, 16132 Genoa, Italy. gabriella.giannini@hsanmartino.liguria.it
authors.forename: Gabriella
authors.initials: G
authors.lastname: Giannini
authors.forename: Valbonesi
authors.initials: V
authors.lastname: Mauro
authors.forename: Tel
authors.initials: T
authors.lastname: Agostino
authors.forename: Bindi
authors.initials: B
authors.lastname: Gianfranco
mesh_terms: D000328:Adult; D000368:Aged; D001771:Blood Banks; D001792:Blood Platelets / Q000737:chemistry* / Q000378:metabolism; D001853:Bone Marrow / Q000378:metabolism; D016025:Bone Transplantation / Q000379:methods; D001842:Bone and Bones / Q000737:chemistry*; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D007568:Jaw; D008297:Male; D008334:Mandible; D008875:Middle Aged; D019647:Oral Surgical Procedures / Q000379:methods; D010983:Plateletpheresis; D019651:Plastic Surgery Procedures; D013515:Surgery, Oral / Q000295:instrumentation* / Q000379:methods*; D013997:Time Factors; D014014:Tissue Adhesives / Q000737:chemistry; D014945:Wound Healing
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives