title: Pulmonary injury from transfusion-related acute lung injury.
abstract: Transfusion-related acute lung injury (TRALI) can be a life-threatening complication of transfusion. In its severe form, it is clinically indistinguishable from acute respiratory distress syndrome. Symptoms typically begin within 4 hours of transfusion. TRALI has been reported after transfusion of all plasma-containing blood components. TRALI is associated with antibodies to white blood cells and biologically active lipids in trans-fused blood components.
authors.affiliation: BloodSource, Sacramento, CA 95816, USA.
authors.forename: Patricia M
authors.initials: PM
authors.lastname: Kopko
authors.forename: Mark A
authors.initials: MA
authors.lastname: Popovsky
mesh_terms: D003937:Diagnosis, Differential; D006098:Granulocytes / Q000276:immunology; D000949:Histocompatibility Antigens Class II / Q000276:immunology; D006801:Humans; D007518:Isoantibodies / Q000032:analysis; D007962:Leukocytes / Q000276:immunology; D009000:Monocytes / Q000276:immunology; D012128:Respiratory Distress Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000503:physiopathology; D065227:Transfusion Reaction
chemical_list: D000949:Histocompatibility Antigens Class II; D007518:Isoantibodies