title: Simultaneous minimizing monitor units and number of segments without leaf end abutment for segmental intensity modulated radiation therapy delivery.
abstract: Leaf end abutment is seldom studied when delivering segmental intensity modulated radiation therapy (IMRT) fields. We developed an efficient leaf sequencing method to eliminate leaf end abutment for segmental IMRT delivery. Our method uses simple matrix and sorting operations to obtain a solution that simultaneously minimizes total monitor units and number of segments without leaf end abutment between segments. We implemented and demonstrated our method for multiple clinical cases. We compared the results of our method with the results from exhaustive search method. We found that our solution without leaf end abutment produced equivalent results to the unconstrained solutions in terms of minimum total monitor units and minimum number of leaf segments. We conclude that the leaf end abutment fields can be avoided without affecting the efficiency of segmental IMRT delivery. The major strength of our method is its simplicity and high computing speed. This potentially provides a useful means for generating segmental IMRT fields that require high spatial resolution or complex intensity distributions.
authors.affiliation: Department of Radiation Oncology, University of Maryland, School of Medicine, Baltimore, Maryland 21201, USA.
authors.forename: Kaile
authors.initials: K
authors.lastname: Li
authors.forename: Jianrong
authors.initials: J
authors.lastname: Dai
authors.forename: Lijun
authors.initials: L
authors.lastname: Ma
mesh_terms: D000465:Algorithms; D006801:Humans; D008962:Models, Theoretical; D010315:Particle Accelerators; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D020266:Radiotherapy, Conformal / Q000295:instrumentation* / Q000379:methods*; D013997:Time Factors