Formulations and use of androgens in women.
The physiology of normal androgen production in women has been poorly understood. Defining an androgen insufficiency state in women, in the absence of adrenal suppression and/or bilateral oophorectomy, has been difficult. Nevertheless, beneficial effects of androgen on many organ systems, including bone and the brain, are well documented. This review discusses the definition of androgen insufficiency, anticipated effects of androgen treatment on several factors of health, and treatment options for women with androgen insufficiency.
Chu
Micheline C
MC
Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, 622 W 168th St, PH 16-77, New York, NY 10032, USA. ral35@columbia.edu
Lobo
Rogerio A
RA
D000465:Algorithms; D000728:Androgens / Q000737:chemistry / Q000172:deficiency / Q000502:physiology / Q000627:therapeutic use; D001682:Biological Availability; D002626:Chemistry, Pharmaceutical; D003663:Decision Trees; D016903:Drug Monitoring; D015914:Estrogen Replacement Therapy / Q000379:methods; D005260:Female; D020249:Hormone Replacement Therapy / Q000379:methods; D006801:Humans; D018579:Patient Selection; D017698:Postmenopause / Q000187:drug effects / Q000502:physiology; D012449:Safety; D012738:Sex Hormone-Binding Globulin / Q000378:metabolism; D013739:Testosterone / Q000737:chemistry / Q000502:physiology / Q000627:therapeutic use; D016387:Women's Health
D000728:Androgens; D012738:Sex Hormone-Binding Globulin; D013739:Testosterone