Current treatment options in squamous cell carcinoma of the oral cavity.
Oral cavity SCC remains a significant health problem and requires a multidisciplinary approach. Treatment with surgery alone or in combination with adjuvant radiotherapy for more advanced lesions is the standard of care. Major advances have been made in surgical approaches,reconstructive options, and the rehabilitation of patients who have oral cavity SCC. These advances have significantly improved disease-specific outcome and quality of life. The future may lie in the development of treatment regimes that combine early detection with organ preservation and result in improved cure rates and quality of life.
Palme
Carsten E
CE
Department of Otolaryngology, University of Toronto, 610 University Avenue, Toronto, ON M5G 2M9, Canada.
Gullane
Patrick J
PJ
Gilbert
Ralph W
RW
D001918:Brachytherapy; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D006258:Head and Neck Neoplasms / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008048:Lip Neoplasms / Q000601:surgery; D008207:Lymphatic Metastasis; D008339:Mandibular Neoplasms / Q000175:diagnosis / Q000601:surgery; D009062:Mouth Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D009367:Neoplasm Staging; D011379:Prognosis; D019651:Plastic Surgery Procedures; D014062:Tongue Neoplasms / Q000532:radiotherapy / Q000601:surgery