Technical aspects in cerebrospinal irradiation.
BACKGROUND
Craniospinal irradiation (CSI) is commonly used for medulloblastoma patients and some others; for example, those with ependymoma. It is a complex technique where accuracy of field placement and choice of irradiation source and energy can play a major role in determining success or failure.


METHODS
A literature review of the techniques used and reported by treatment centers was undertaken.


RESULTS
Great variability was found in methods and practices. This is striking because many hospitals treat fewer than five patients per year.


CONCLUSIONS
Standardized techniques with strict central review for quality control before therapy is initiated should become the norm. Standardization is especially important when clinical trials are planned. Valid outcome data depend on CSI uniformity.
Bernier
Valérie
V
Department of Radiation Oncology, Centre Alexis Vautrin, Vandoeuvre-les-Nancy, France. v.bernier@nancy.fnclcc.fr
D002528:Cerebellar Neoplasms / Q000532:radiotherapy*; D002648:Child; D016371:Cranial Irradiation / Q000379:methods*; D006801:Humans; D008527:Medulloblastoma / Q000532:radiotherapy*; D008722:Methods; D011187:Posture; D011874:Radiometry