Computed tomography (CT) evaluation of breast cancer patients with osteolytic bone metastases undergoing palliative radiotherapy--a feasibility study.
Twenty-five patients with osteolytic metastases had computed tomography (CT) scans before and 3 months after palliative radiotherapy. The median % density change following single 8Gy, 20Gy/5#, 30Gy/10# were: 128 (range 98-255), 141 (79-342), and 145 (65-235), respectively. It is feasible to evaluate remineralization of osteolytic lesions with palliative radiotherapy.
Chow
Edward
E
Rapid Response Radiotherapy Program and Bone Metastases Site Group, Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5.
Holden
Lori
L
Rubenstein
Joel
J
Christakis
Monique
M
Sixel
Katharina
K
Vidmar
Marjan
M
Finkelstein
Joel
J
Hayter
Charles
C
Loblaw
Andrew
A
Wong
Rebecca
R
Szumacher
Ewa
E
Danjoux
Cyril
C
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy / Q000556:secondary*; D001943:Breast Neoplasms / Q000473:pathology*; D005240:Feasibility Studies; D006801:Humans; D008875:Middle Aged; D010014:Osteolysis / Q000000981:diagnostic imaging; D010166:Palliative Care; D011879:Radiotherapy Dosage; D014057:Tomography, X-Ray Computed