title: Laparoscopic versus conventional open resection of rectal carcinoma: A clinical comparative study.
abstract: OBJECTIVE
  To evaluate the feasibility of laparoscopic resection of rectal carcinoma and to compare the short-term outcome of laparoscopic procedure with conventional open surgery for rectal cancer.
  
  
  METHODS
  Thirty-eight patients with rectal cancer were included in a prospective non-randomized study. The patients were assigned to laparoscopic (n=18) or open (n=18) colorectal resection. Case selection, surgical technique, and clinical and pathological results were reviewed.
  
  
  RESULTS
  The operative time was longer in laparoscopic resection group (LAP) than in open resection group (189+/-18 min vs 146+/-22 min, P<0.05). Intraoperative blood loss and postoperative complications were less in LAP resection group than in open resection group. An earlier return of bowel motility was observed after laparoscopic surgery. The overall postoperative morbidity was 5.6% in the LAP resection group and 27.8% in open resection group (P<0.05). No anastomotic leakage was found in both groups. The pathologic examination showed that the length of the resected specimen, the mean number of harvested lymph nodes in laparoscopic resection group were comparable to those in open resection group.
  
  
  CONCLUSIONS
  Laparoscopic total mesorectal excision (TME) for rectal cancer is a feasible but technically demanding procedure. The present study demonstrates the safety of the procedure, while oncologic results are comparable to the open surgery, with a favorable short-term outcome.
authors.affiliation: Department of Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanijng 210029, Jiangsu Province, China. wuwenxi@yahoo.com
authors.forename: Wen-Xi
authors.initials: WX
authors.lastname: Wu
authors.forename: Yao-Min
authors.initials: YM
authors.lastname: Sun
authors.forename: Yi-Bin
authors.initials: YB
authors.lastname: Hua
authors.forename: Li-Zong
authors.initials: LZ
authors.lastname: Shen
mesh_terms: D005240:Feasibility Studies; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality; D011446:Prospective Studies; D012004:Rectal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome