Familial Lassueur-Graham-Little-Piccardi syndrome.
Lassueur-Graham-Little-Piccardi syndrome (LGLPS) is a rare lichenoid dermatosis characterized by progressive cicatricial alopecia of the scalp, loss of pubic and axillary hairs and keratosis pilaris. The syndrome is considered a form of follicular lichen planus (LP). Although the familial occurrence of LP is a well-described phenomenon, no familial case of LGLPS has ever been reported. We describe the occurrence of LGLPS in a mother and her daughter. HLA typing revealed HLA-DR1 in both patients. Topical tacrolimus was of partial benefit in the daughter.
Viglizzo
Gianmaria
G
Department of Endocrinologic and Metabolic Diseases, University of Genoa, Genoa, Italy.
Verrini
Anna
A
Rongioletti
Franco
F
D000328:Adult; D000505:Alopecia / Q000150:complications / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D001707:Biopsy, Needle; D002921:Cicatrix / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007642:Keratosis / Q000150:complications / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D008010:Lichen Planus / Q000150:complications / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D008875:Middle Aged; D010375:Pedigree; D018570:Risk Assessment; D012536:Scalp Dermatoses / Q000150:complications / Q000188:drug therapy / Q000235:genetics / Q000473:pathology; D012720:Severity of Illness Index; D013577:Syndrome; D016896:Treatment Outcome
D007166:Immunosuppressive Agents