Use of allene in 1,3-dipolar addition to a carbonyl ylide: syntheses of 3-hydroxy-cis-nemorensic acid and nemorensic acid.
1,3-Dipolar addition of allene to the carbonyl ylide derived from 6-diazoheptane-2,5-dione is the key step in syntheses of 3-hydroxy-cis-nemorensic acid and nemorensic acid.
Hodgson
David M
DM
Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, UKOX1 3TA. david.hodgson@chem.ox.ac.uk
Le Strat
Frédéric
F
D000466:Alkadienes / Q000737:chemistry*; D001391:Azo Compounds / Q000737:chemistry; D005663:Furans / Q000138:chemical synthesis*; D006536:Heptanes / Q000737:chemistry; D008956:Models, Chemical; D011763:Pyrrolizidine Alkaloids / Q000138:chemical synthesis*; D013237:Stereoisomerism
C499346:3-hydroxy-cis-nemorensic acid; D000466:Alkadienes; D001391:Azo Compounds; D005663:Furans; D006536:Heptanes; D011763:Pyrrolizidine Alkaloids; C458241:nemorensic acid; C025947:propadiene