Usefulness of Toxoplasma gondii-specific recombinant antigens in serodiagnosis of human toxoplasmosis.
Toxoplasma gondii SAG1, GRA1, and GRA7 recombinant antigens may be regarded as tools for the detection of T. gondii immunoglobulin G antibodies in persons with chronic and acute toxoplasmosis. GRA7 is more correlated with acute toxoplasmosis. A combination of these antigens will increase the sensitivity of enzyme-linked immunosorbent assays.
Pietkiewicz
H
H
Department of Tropical Parasitology, Interfaculty Institute of Maritime and Tropical Medicine, Medical University of Gdańsk.
Hiszczyńska-Sawicka
E
E
Kur
J
J
Petersen
E
E
Nielsen
H V
HV
Stankiewicz
M
M
Andrzejewska
I
I
Myjak
P
P
D000208:Acute Disease; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D000953:Antigens, Protozoan / Q000235:genetics / Q000276:immunology*; D002908:Chronic Disease; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D015800:Protozoan Proteins / Q000235:genetics / Q000276:immunology; D011994:Recombinant Proteins / Q000276:immunology*; D012680:Sensitivity and Specificity; D012698:Serologic Tests; D014122:Toxoplasma / Q000235:genetics / Q000276:immunology*; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000469:parasitology
D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan; C412913:GRA1 antigen; C112573:GRA7 protein, Toxoplasma gondii; D007074:Immunoglobulin G; D015800:Protozoan Proteins; D011994:Recombinant Proteins; C047168:SAG1 antigen, Toxoplasma