title: [Structure and degradation property of the PVA-collagen complex drug membrane].
abstract: OBJECTIVE
  To investigate the structure and degradation property of the polyvinyl alcohol (PVA)-collagen complex drug membrane.
  
  
  METHODS
  Drug collagen membrane was complexed with PVA. The physical and chemical properties of the membrane were characterized by transmission electron microscopy, scanning electron microscope, forier transform-infrared spectroscopy and differential scanning calorimetry. Degradation experiment was performed to determine the degradation property of membrane and a degradation curve was therefor drawn.
  
  
  RESULTS
  The thermodynamic stability of collagen membrane was not destroyed by adding PVA. Collagen had good compatibility with PVA. Compared with collagen membrane, collagen-PVA complex membrane had smaller and evener pores. Adding PVA decreased the degradation rate of membrane.
  
  
  CONCLUSIONS
  PVA-collagen membrane has better microstructure and antidegradation property than collagen membrane.
authors.affiliation: Biomaterials Lab, Institute of Biomedical Engineering, CAMS and PUMC, Tianjin 300192, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Liang
authors.forename: Ling-rong
authors.initials: LR
authors.lastname: Liu
authors.forename: Qi-qing
authors.initials: QQ
authors.lastname: Zhang
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D003094:Collagen / Q000737:chemistry* / Q000648:ultrastructure; D006801:Humans; D008566:Membranes; D011142:Polyvinyl Alcohol / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D001672:Biocompatible Materials; D011142:Polyvinyl Alcohol; D003094:Collagen