Effect of dominance on heterozygosity and the fixation probability in a subdivided population.
Under the assumptions of a subdivided population and the presence of dominance for fitness, the expected sum of heterozygosity in the total population during the lifetime of mutant was investigated. It was shown analytically and by computer simulations that in the island model the effect of dominance on the expected sum of heterozygosity decreases as the migration rate decreases and is lost almost completely when the migration rate is very low. In addition to the expected sum of heterozygosity, the fixation probability of mutant was also investigated. The effect of dominance on the fixation probability also decreases as the migration rate decreases but is not completely lost when the migration rate is very low.
Nishino
Jo
J
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Japan.
Tajima
Fumio
F
D003198:Computer Simulation; D005799:Genes, Dominant; D005828:Genetics, Population; D006579:Heterozygote; D008957:Models, Genetic