[Relationship between the endocervical mycoplasma infection and spontaneous abortion due to early embryonic death].
OBJECTIVE
To study the relationship between endocervical mycoplasma infection and the spontaneous abortion due to the early embryonic death and the drug sensitivity to mycoplasma.


METHODS
Endocervical swabs were taken from fifty normal pregnant women (normal group) and fifty-eight women with spontaneous abortion due to embryonic death. The swabs were used for ureaplasma urealyticum (UU) and mycoplasma hominis (MH) Cultivation respectively. The isolation rates of the two groups were comparedf.


RESULTS
(1) In the embryonic death group, the positive rates of UU, MH and UU mixed with MH were 74.1% (43/58), 27.6% (16/58) and 20.7% (12/58) separately. In the normal female group, however, the positive rates correspondingly were the UU 48.0% (24/50), the MH 10.0% (5/50) and the UU mixed with MH 4.0% (2/50). There had significant differences of the positive rates between the two groups (P < 0.01, P < 0.05, P < 0.05). (2) Drug sensitivity rates to mycoplasma were roxithromycin 94.6%, doxycycline 54.5% and ofloxacin 32.8%. (3) The infection rate of mycoplasma had no positive relationship with times of early embryonic death.


CONCLUSIONS
(1) The endocervical mycoplasma infection could be one of the causes leading to the early embryonic death. (2) Roxithromycin was the most sensitive drug tested to mycoplasma.
Ye
Ling-ling
LL
Zhoushan Maternal and Child Health Hospital, Zhejiang Province 316000, China.
Zhang
Bi-yun
BY
Cao
Wen-li
WL
D000022:Abortion, Spontaneous / Q000209:etiology*; D000328:Adult; D004318:Doxycycline / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D009174:Mycoplasma / Q000187:drug effects / Q000302:isolation & purification*; D009175:Mycoplasma Infections / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D015242:Ofloxacin / Q000627:therapeutic use; D015575:Roxithromycin / Q000627:therapeutic use; D002575:Uterine Cervicitis / Q000382:microbiology; D014626:Vaginal Smears
D015575:Roxithromycin; D015242:Ofloxacin; D004318:Doxycycline