Treatment of memory impairment, vertigo and tinnitus in the elderly with piribedil in an Indian general practice setting.
Age-related dopamine decline leads to memory impairment, vertigo or tinnitus leading to a reduced quality of life in the elderly. This study demonstrates the efficacy and acceptability of piribedil, a dopamine agonist, in improving these conditions. Of the 515 patients included in the study, there was complete resolution of memory impairment, vertigo and tinnitus in 103 patients (20%), improvement in 374 cases (72.6%), with 38 cases (7.4%) showing no change after one month's treatment with piribedil. The treatment was well accepted with a low frequency of side-effects and full compliance with daily medication.
Hastak
S M
SM
Lilavati Hospital, Mumbai 400 050.
D000368:Aged; D000369:Aged, 80 and over; D018491:Dopamine Agonists / Q000627:therapeutic use*; D005194:Family Practice; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D008569:Memory Disorders / Q000188:drug therapy*; D008875:Middle Aged; D010891:Piribedil / Q000627:therapeutic use*; D014012:Tinnitus / Q000188:drug therapy*; D016896:Treatment Outcome; D014717:Vertigo / Q000188:drug therapy*
D018491:Dopamine Agonists; D010891:Piribedil