Relation of homocysteine and C-reactive protein to urinary albumin loss.
This study shows that elevated high-sensitivity C-reactive protein and plasma total homocysteine contribute independently to the likelihood of an increased urinary albumin:creatinine ratio. This result suggests that total homocysteine and C-reactive protein may be acting by separate mechanistic pathways.
Seshadri
Niranjan
N
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Messerli
Adrian W
AW
Acharya
Naveen
N
Pearce
Gregory L
GL
Jacobsen
Donald W
DW
Pohl
Marc A
MA
Robinson
Killian
K
Sprecher
Dennis L
DL
D000328:Adult; D000368:Aged; D000419:Albuminuria / Q000097:blood* / Q000652:urine*; D002097:C-Reactive Protein / Q000378:metabolism*; D003404:Creatinine / Q000652:urine*; D004730:Endothelium, Vascular / Q000502:physiology*; D005260:Female; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014652:Vascular Diseases / Q000378:metabolism
D006710:Homocysteine; D002097:C-Reactive Protein; D003404:Creatinine