[Endosaccular Onyx injection and endovascular treatment with parent artery reconstruction technique in cerebral aneurysms].
OBJECTIVE
The aim of this study was to test the feasibility and efficacy of the treatment of wide-necked and giant intracranial aneurysms with a new liquid embolic agent.


METHODS
During injection of Onyx, an occlusion balloon with or without an intracranial stent was inflated in the parent artery. Sixty-seven patients harboring 72 intracranial aneurysms, most of which being giant or wide-necked, were successfully treated with this technique.


RESULTS
Seventy of 72 aneurysms were internal carotid artery aneurysms. Of these, 37 were ophthalmic (53%), 18 were cavernous (26%) and 15 were petrous (21%) internal carotid artery aneurysms. One patient had 2 aneurysms located at the basilar and superior cerebellar arteries. Fifty-three aneurysms were treated with the balloon remodelling technique and 19 were treated with the use of an intracranial stent. Recanalisation was found in 8 of 15 giant aneurysms which were treated with the balloon remodelling technique and 3 of these underwent a second treatment in which stents were used. Mortality occurred in 3 patients.


CONCLUSIONS
Onyx embolisation with balloon or stent remodelling technique is a feasible and effective method in the treatment of high-risk giant or wide-necked intracranial aneurysms which are difficult to treat with other endovascular or microsurgical techniques.
Cil
Barbaros E
BE
Hacettepe Universitesi Tip Fakültesi, Radyoloji Anabilim Dali, Ankara, Turkey.
Akmangit
Ilkay
I
Arat
Anil
A
Cekirge
Saruhan
S
Saatçi
Işil
I
D000293:Adolescent; D000328:Adult; D021721:Balloon Occlusion; D002343:Carotid Artery, Internal; D002648:Child; D004121:Dimethyl Sulfoxide / Q000008:administration & dosage / Q000627:therapeutic use*; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011145:Polyvinyls / Q000008:administration & dosage / Q000627:therapeutic use*; D011859:Radiography; D015642:Radiology, Interventional; D015607:Stents; D016896:Treatment Outcome
C450660:Onyx copolymer; D011145:Polyvinyls; D004121:Dimethyl Sulfoxide