title: An improved total synthesis of triciribine: a tricyclic nucleoside with antineoplastic and antiviral properties.
abstract: We describe an efficient total synthesis of triciribine, a tricyclic nucleoside with antineoplastic and antiviral properties, starting from 4-amino-6-bromo-5-cyanopyrrolo[2,3-d]pyrimidine.
authors.affiliation: Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA. anthony.porcari@pfizer.com
authors.forename: Anthony R
authors.initials: AR
authors.lastname: Porcari
authors.forename: Leroy B
authors.initials: LB
authors.lastname: Townsend
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D000998:Antiviral Agents / Q000138:chemical synthesis*; D006801:Humans; D012263:Ribonucleosides / Q000138:chemical synthesis*; D014127:Toyocamycin / Q000737:chemistry; D014777:Virus Diseases / Q000188:drug therapy*; D014780:Viruses / Q000187:drug effects*
chemical_list: D000970:Antineoplastic Agents; D000998:Antiviral Agents; D012263:Ribonucleosides; C023764:triciribine; D014127:Toyocamycin