Acetate enhances citric acid production by Yarrowia lipolytica when grown on sunflower oil.
It was discovered that the addition of 10 g/l acetate to a medium containing 30 g/l sunflower oil caused a drastic increase in citric acid production by Yarrowia lipolytica UOFS Y-1701 i.e. from 0.5 g/l in the absence of acetate to 18.7 g/l in the presence of acetate. Similarly, the ratio of citric acid:isocitric acid increased significantly from 1.7:1 in the absence of acetate to 3.7:1 in the presence of acetate after 240 h of growth.
Venter
T
T
Department of Microbial, Biochemical and Food Biotechnology, University of the Free State, Bloemfontein, South Africa.
Kock
J L F
JL
Botes
P J
PJ
Smit
M S
MS
Hugo
A
A
Joseph
M
M
D000085:Acetates / Q000494:pharmacology*; D019343:Citric Acid / Q000378:metabolism*; D007523:Isocitrates / Q000378:metabolism; D010938:Plant Oils / Q000378:metabolism*; D000074242:Sunflower Oil; D025062:Yarrowia / Q000187:drug effects* / Q000378:metabolism*
D000085:Acetates; D007523:Isocitrates; D010938:Plant Oils; D000074242:Sunflower Oil; D019343:Citric Acid; C034219:isocitric acid