[Stem cell factor (SCF) in clinical practice].
Stem cell factor (SCF) is a hematopoietic factor active in the early stages of hematopoiesis. Recognition of biological properties of SCF made a hope for its use in diagnosis and therapy of many diseases, especially neoplasmas. We present a characterization of SCF, its attempts to use in medicine and future possibilities of application. We describe also possibilities for clinical use of soluble receptor (s-kit) and inhibitors of SCF.
Jakimiuk
Barbara
B
Zakład Diagnostyki Biochemicznej Akademii Medycznej, 15-274 Białystok, ul. Waszyngtona 15 a.
Mroczko
Barbara
B
Szmitkowski
Maciej
M
D014408:Biomarkers, Tumor; D006410:Hematopoiesis / Q000502:physiology; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy; D019009:Proto-Oncogene Proteins c-kit / Q000627:therapeutic use*; D019089:Stem Cell Factor / Q000502:physiology*
D014408:Biomarkers, Tumor; D019089:Stem Cell Factor; D019009:Proto-Oncogene Proteins c-kit