title: Tumour suppression: disruption of HAUSP gene stabilizes p53.
authors.affiliation: Howard Hughes Medical Institute, The Sidney Kimmel Comprehensive Cancer Center, and Program in Cellular and Molecular Medicine, The Johns Hopkins University Medical Institutions, Baltimore, Maryland 21231, USA.
authors.forename: Jordan M
authors.initials: JM
authors.lastname: Cummins
authors.forename: Carlo
authors.initials: C
authors.lastname: Rago
authors.forename: Manu
authors.initials: M
authors.lastname: Kohli
authors.forename: Kenneth W
authors.initials: KW
authors.lastname: Kinzler
authors.forename: Christoph
authors.initials: C
authors.lastname: Lengauer
authors.forename: Bert
authors.initials: B
authors.lastname: Vogelstein
mesh_terms: D000483:Alleles; D045744:Cell Line, Tumor; D015179:Colorectal Neoplasms / Q000378:metabolism* / Q000473:pathology; D010450:Endopeptidases / Q000235:genetics / Q000378:metabolism*; D017353:Gene Deletion; D006801:Humans; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism*; D025521:Tumor Suppressor Proteins / Q000235:genetics / Q000378:metabolism*; D025801:Ubiquitin / Q000378:metabolism; D043222:Ubiquitin Thiolesterase; D000076084:Ubiquitin-Specific Peptidase 7; D015854:Up-Regulation
chemical_list: D016159:Tumor Suppressor Protein p53; D025521:Tumor Suppressor Proteins; D025801:Ubiquitin; D010450:Endopeptidases; C464569:USP7 protein, human; D043222:Ubiquitin Thiolesterase; D000076084:Ubiquitin-Specific Peptidase 7