[The new measurement technics in biology and medicine--atomic force microscopy].
Scanning probe microscopy (SPM) has recently become the most dynamically developing technique employed in research investigations. Atomic force microscopy (AFM) that uses a digitally-controlled scanner and a cantilever system with a measurement tip shaped as a cone with the apex radius of 2-50 nm and the application force of 10(-10) N, as well as a system of recording detectors, has allowed for identification of numerous biological structures in a nanometer scale. The paper presents a review of measurement methods that employ the atomic force microscopy and are being used in medicine and biology, along with major achievements accomplished owing to this technique by various investigators, including the authors themselves.
Targosz
Marta
M
Instytut Fizyki Uniwersytetu Jagiellońskiego w Krakowie.
Szymoński
Marek
M
Miklaszewska
Monika
M
Pietrzyk
Jacek A
JA
Sułowicz
Władysław
W
Rumian
Roman
R
Krawentek
Lidia
L
D000818:Animals; D006801:Humans; D018625:Microscopy, Atomic Force / Q000379:methods