Unusual widespread metastatic presentation of mixed medullary-follicular thyroid carcinoma.
Mixed medullary-follicular thyroid carcinoma (MMFTC) is a rare tumor with a metastatic behavior that has not been fully appreciated. Scintigraphy and radioiodine entrapment propensity of its metastases remains largely undescribed. The authors present a case of MMFTC with widespread bone and soft-tissue metastases, where every known site of metastases concentrated radioiodine intensely. The patient responded well to radioiodine therapy. The report suggests that the tumor may have a propensity to metastasize to the skeleton, and the metastases retain the ability to accumulate radioiodine.
Bhatnagar
Parul
P
Institute of Nuclear Medicine and Allied Sciences, Delhi, India. drparul_bhatnagar@hotmail.com
Bhatnagar
Aseem
A
Kishan
Sawroop
S
Bal
C S
CS
Saran
Ravinder Kumar
RK
Sinha
Sanjeev
S
Kashyap
Ravi
R
D018263:Adenocarcinoma, Follicular / Q000000981:diagnostic imaging / Q000556:secondary*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D018276:Carcinoma, Medullary / Q000000981:diagnostic imaging / Q000556:secondary*; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D013669:Technetium Tc 99m Medronate; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*
D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate