title: Model based soft-sensor for on-line determination of substrate.
abstract: A software sensor for on-line determination of substrate was developed based on a model for fed-batch alcoholic fermentation process and on-line measured signals of ethanol, biomass, and feed flow. The ethanol and biomass signals were obtained using a colorimetric biosensor and an optical sensor developed in previous works that permitted determination of ethanol at a concentration of 0-40 g/L and biomass of 0-60 g/L. The volume in the fermentor could be continuously calculated using the total measured signal of the feed flow. The results obtained show that the model used is adequate for the proposed software sensor and determines continuously the substrate concentration with efficiency and security during the fermentation process.
authors.affiliation: Departamento de Engenharia Química, Escola de Química, Universidade Federal do Rio de Janeiro, CT-Bl E, sl 211, Rio de Janeiro, Brasil.
authors.forename: Andréa M
authors.initials: AM
authors.lastname: Salgado
authors.forename: Rossana O M
authors.initials: RO
authors.lastname: Folly
authors.forename: Belkis
authors.initials: B
authors.lastname: Valdman
authors.forename: Francisco
authors.initials: F
authors.lastname: Valero
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D018533:Biomass; D001709:Biotechnology / Q000379:methods*; D002241:Carbohydrates / Q000737:chemistry; D000431:Ethanol / Q000737:chemistry; D005285:Fermentation; D007700:Kinetics; D008956:Models, Chemical; D008962:Models, Theoretical; D012441:Saccharomyces cerevisiae / Q000378:metabolism; D013997:Time Factors
chemical_list: D000438:Alcohols; D002241:Carbohydrates; D000431:Ethanol