Centrosomes: hooked on the nucleus.
A recent study has shown that the Hook protein ZYG-12 of Caenorhabditis elegans is essential for attachment of the centrosome to the nucleus. The results suggest a novel mechanism for the tight coupling between these two organelles, and shed new light on its biological significance.
Gönczy
Pierre
P
ISREC, 155, ch. des Boveresses, CH-1066 Epalinges / Lausanne, Switzerland. Pierre.Gonczy@isrec.unil.ch
D000818:Animals; D017173:Caenorhabditis elegans; D029742:Caenorhabditis elegans Proteins / Q000235:genetics / Q000378:metabolism*; D018797:Cell Cycle Proteins / Q000235:genetics / Q000378:metabolism*; D002467:Cell Nucleus / Q000378:metabolism*; D018385:Centrosome / Q000378:metabolism* / Q000502:physiology*; D008954:Models, Biological
D029742:Caenorhabditis elegans Proteins; D018797:Cell Cycle Proteins; C480800:zyg-12 protein, C elegans