title: [A population-based epidemiologic study of irritable bowel syndrome in Guangdong province].
abstract: OBJECTIVE
  To explore the prevalence of irritable bowel syndrome (IBS) and its risk factors in Guangdong province.
  
  
  METHODS
  A questionnaire was used to screen IBS by face-to-face interviews according to Manning (modified including symptoms of constipation) and Rome II criteria. Random clustered sampling involving permanent inhabitants aged 18 - 80 years was carried out under stratification of urban and suburban areas. Potential risk factors were explored by comparing the frequencies among IBS group and non-IBS group using chi(2) and logistic analysis of multivariate adjusted for age and gender.
  
  
  RESULTS
  A total of 4178 residents (male 1907, female 2271) were investigated. Mean age among the responders was (43 +/- 14) years. The response rate was 98%. The adjusted prevalence of IBS in Guangdong province is 5.67% according to the modified Rome II criteria, and is 11.50% according to Manning criteria. There is no difference between urban and suburban areas. The female was predominant in IBS, and the ratio of male to female was 1:1.25 (Rome II) and 1:1.34 (Manning). The age was poorly correlated with the prevalence. Events including history of analgesic use such as NSAID (OR = 3.83), history of food allergies (OR = 2.68), psychological distress (OR = 2.18), life events (OR = 1.89), history of dysentery (OR = 1.63) and negative coping style (OR = 1.28) are highly associated with IBS (P < 0.05).
  
  
  CONCLUSIONS
  IBS is a common disorder in Guangdong Province which deserves greater care and further investigation.
authors.affiliation: Department of Gastroenterology, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.
authors.forename: Li-shou
authors.initials: LS
authors.lastname: Xiong
authors.forename: Min-hu
authors.initials: MH
authors.lastname: Chen
authors.forename: Hui-xin
authors.initials: HX
authors.lastname: Chen
authors.forename: An-gao
authors.initials: AG
authors.lastname: Xu
authors.forename: Wei-an
authors.initials: WA
authors.lastname: Wang
authors.forename: Pin-jin
authors.initials: PJ
authors.lastname: Hu
mesh_terms: D000328:Adult; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000453:epidemiology*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D015995:Prevalence; D012307:Risk Factors; D011795:Surveys and Questionnaires