[Probable mechanisms of the regulation in the jejunum motility].
It is a well-known fact that serotonin has a stimulative action on the motor-secretory activity of the gastrointestinal tract. Activation of 5HT3,4-receptors regulates neuronal responses of this action; it is possible to regulate efferent reactions by activating 5HT1,2-receptors (1, 2, 3). Carcinoid cells containing 5HT have 5HT3 and 5HT4 receptors on their superficial membranes. The object of this research was to determine the possible participation of serotonergic structures in the regulation of the jejunum motility.
Lychkova
A E
AE
Central Scientific Research Institute of Gastroenterology, Russian State Medical University, Moscow.
Savchuk
V I
VI
Smirnov
V M
VM
Trubitsyna
I E
IE
D000818:Animals; D005508:Food Deprivation / Q000502:physiology*; D005769:Gastrointestinal Motility / Q000502:physiology*; D007413:Intestinal Mucosa / Q000378:metabolism; D007583:Jejunum / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D012701:Serotonin / Q000097:blood / Q000378:metabolism; D012702:Serotonin Antagonists / Q000494:pharmacology
D012702:Serotonin Antagonists; D012701:Serotonin