Introducing a novel class of four-component reactions.
A novel four-component reaction approach to the efficient synthesis of triamide and amidodiester derivatives using amines or alcohols, aldehydes and alkyl or aryl isocyanides in the presence of Meldrum's acid as a CH acid, instead of carboxylic acid of Ugi four-component reaction, was studied.
Shaabani
Ahmad
A
Department of Chemistry, Shahid Beheshti University, 1983963113 Tehran, Iran. a-shaabani@cc.sbu.ac.ir
Teimouri
Mohammad Bagher
MB
Bazgir
Ayoob
A
Bijanzadeh
Hamid Reza
HR
D000438:Alcohols / Q000737:chemistry*; D000447:Aldehydes / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D000605:Amino Alcohols / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D003486:Cyanides / Q000737:chemistry*; D015394:Molecular Structure
D000438:Alcohols; D000447:Aldehydes; D000577:Amides; D000588:Amines; D000605:Amino Alcohols; D002264:Carboxylic Acids; D003486:Cyanides