title: Aphrodisiac activity of Butea frondosa Koen. ex Roxb. extract in male rats.
abstract: In the present study, the aphrodisiac activity of Butea frondonsa Koen. ex Roxb (Papillionaceae) bark extract was investigated. The extract (400 mg/kg body wt./day) was administered orally by gavage for 28 days. Mount latency (ML), intromission latency (IL), ejaculation latency (EL), mounting frequency (MF), intromission frequency (IF), ejaculation frequency (EF) and post-ejaculatory interval (PEI) were the parameters observed before and during the sexual behavior study at day 0, 7, 10, 14, 21, and 28. The extract reduced significantly ML, IL, EL and PEI (p < 0.05). The extract also increased significantly MF, IF and EF (p < 0.05). These effects were observed in sexually active and inactive male rats.
authors.affiliation: Department of Pharmacology and Toxicology, C. L. Baid Metha College of Pharmacy, Thorapakkam, Old Mahabalipuram Road, Chennai, India. ramsnetin@yahoo.com
authors.forename: S
authors.initials: S
authors.lastname: Ramachandran
authors.forename: Y
authors.initials: Y
authors.lastname: Sridhar
authors.forename: S Kishore Gnana
authors.initials: SK
authors.lastname: Sam
authors.forename: M
authors.initials: M
authors.lastname: Saravanan
authors.forename: J Thomas
authors.initials: JT
authors.lastname: Leonard
authors.forename: N
authors.initials: N
authors.lastname: Anbalagan
authors.forename: S K
authors.initials: SK
authors.lastname: Sridhar
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001046:Aphrodisiacs / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D031290:Butea; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar; D012726:Sexual Behavior, Animal / Q000187:drug effects*
chemical_list: D001046:Aphrodisiacs; D010936:Plant Extracts