title: [Hematological and histopathological evaluation of BALB/c and C57BL/6 mice exposed to Cytoplasmic Repetitive Antigen and Flagellar Repetitive Antigen recombinant antigens of Trypanosoma cruzi].
abstract: The Cytoplasmic Repetitive Antigen and Flagellar Repetitive Antigen recombinant antigens of Trypanosoma cruzi were inoculated into BALB/c and C57BL/6 mice and its effects evaluated at hematological and histopathological levels. The results showed that the histological pattern of the organs and the hematological profile of mice were not modified suggesting that these antigens are not harmful for the animal.
authors.affiliation: Departamento de Imunologia do Centro de Pesquisas Aggeu Magalhães da Fundação Oswaldo Cruz, Recife, PE.
authors.forename: Valéria Rêgo Alves
authors.initials: VR
authors.lastname: Pereira
authors.forename: Virginia Maria Barros
authors.initials: VM
authors.lastname: de Lorena
authors.forename: Ana Paula
authors.initials: AP
authors.lastname: Galvão-da Silva
authors.forename: Mineo
authors.initials: M
authors.lastname: Nakazawa
authors.forename: Edimilson Domingos
authors.initials: ED
authors.lastname: da Silva
authors.forename: Antonio Gomes Pinto
authors.initials: AG
authors.lastname: Ferreira
authors.forename: Ulisses
authors.initials: U
authors.lastname: Montarroyos
authors.forename: Eridan de Medeiros
authors.initials: Ede M
authors.lastname: Coutinho
authors.forename: Yara de Miranda
authors.initials: Yde M
authors.lastname: Gomes
mesh_terms: D000818:Animals; D000953:Antigens, Protozoan / Q000008:administration & dosage / Q000276:immunology*; D014355:Chagas Disease / Q000097:blood / Q000276:immunology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000276:immunology; D014349:Trypanosoma cruzi / Q000276:immunology*
chemical_list: D000953:Antigens, Protozoan; D011994:Recombinant Proteins