Macrolide resistance determinants of invasive and noninvasive group B streptococci in a Turkish hospital.
Macrolide resistance in 156 consecutive group B streptococcal isolates was investigated. Thirty-five isolates (22.4%) had inducible (80%) or constitutive (20%) erythromycin resistance. The genes responsible were erm(B), erm(A) subclass erm(TR), and erm(B) plus erm(TR) in 62.9, 2.9, and 8.6% of isolates, respectively. Nine isolates (25.7%) harbored neither mef nor detectable erm genes.
Acikgoz
Ziya Cibali
ZC
Department of Microbiology and Clinical Microbiology, Fatih University Faculty of Medicine, Fatih Universitesi Hastanesi, 06510 Emek, Turkey. zcacikgoz@yahoo.com
Almayanlar
Ebru
E
Gamberzade
Sohret
S
Gocer
Safiye
S
D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002981:Clindamycin / Q000494:pharmacology; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004917:Erythromycin / Q000494:pharmacology; D005260:Female; D005798:Genes, Bacterial / Q000235:genetics / Q000502:physiology; D006801:Humans; D018942:Macrolides / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D012007:Rectum / Q000382:microbiology; D013290:Streptococcal Infections / Q000453:epidemiology / Q000382:microbiology; D013292:Streptococcus agalactiae / Q000187:drug effects* / Q000235:genetics*; D014421:Turkey / Q000453:epidemiology; D014621:Vagina / Q000382:microbiology
D000900:Anti-Bacterial Agents; D018942:Macrolides; D002981:Clindamycin; D004917:Erythromycin