Common variable immunodeficiency and breast cancer.
We describe two women with early onset breast cancer (at ages 31 and 38) who were found to have common variable immunodeficiency (CVID). Both women had a history of frequent and unusual bacterial infections. The incidence of breast cancer in young women and of CVID are both low, and the coincident diagnosis in two patients from a relatively small population base suggests the possibility of a pathophysiologic or causal relationship.
Mehta
Apurva C
AC
Department of Medicine, SUNY Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA.
Faber-Langendoen
Kathy
K
Duggan
David B
DB
D000328:Adult; D017668:Age of Onset; D001424:Bacterial Infections; D001943:Breast Neoplasms / Q000150:complications* / Q000276:immunology*; D017074:Common Variable Immunodeficiency / Q000150:complications*; D005260:Female; D006801:Humans