Dietary exposure to a group of naturally produced organohalogens (halogenated dimethyl bipyrroles) via consumption of fish and seafood.
Concentrations of four naturally produced halogenated dimethyl bipyrroles (HDBPs) were quantitated in marine fish (n = 10), freshwater fish (n = 10), canned fish (n = 10), and shrimp composites (n = 10) collected from 1992 to 2002 for the Canadian Total Diet Study. Canned fish composites composed of epipelagic higher trophic level species contained the highest concentration of HDBPs (SigmaHDBP geometric mean +/- standard error = 880 +/- 690 pg/g of wet weight, n = 10), which was significantly higher than that found in the other three composites. There were no significant temporal trends of HDBP concentrations observed for any of the four composites. The estimated daily intake of HDBPs via consumption of fish and seafood was determined to be 53 pg/kg of body mass/day and 0.10 pg of TEQ/kg of body mass/day when transformed to 2,3,7,8-tetrachlorodibenzodioxin equivalents (TEQs). In the canned fish and shrimp composites collected in 1998, HDBPs accounted for approximately 98 and 19%, respectively, of the total quantitated TEQ (which included polychlorinated biphenyls, dioxins, and furans). The results of this study provide the first estimate of human exposure to naturally produced bioaccumulating organohalogens.
Tittlemier
Sheryl A
SA
Food Research Division, Banting Research Centre 2203D, Health Canada, Ottawa, Ontario, Canada K1A 0L2. sheryl_tittlemier@hc-sc.gc.ca
D000818:Animals; D002170:Canada; D004032:Diet; D004781:Environmental Exposure; D005396:Fish Products / Q000032:analysis; D005399:Fishes; D005506:Food Contamination / Q000032:analysis*; D006801:Humans; D006846:Hydrocarbons, Halogenated / Q000032:analysis*; D011758:Pyrroles / Q000032:analysis; D017747:Seafood / Q000032:analysis*
D006846:Hydrocarbons, Halogenated; D011758:Pyrroles