title: [Dynamics in the local and systemic immune factors in patients with cystic transformation of the bile duct].
abstract: Cystic transformation of biliary ducts (CTBD) is a rare inborn anomaly of the biliary system development. For the patients with CTBD quite high metabolic activity of neutrophils according to data of spontaneous test with nitroblue tetrazolium (NBT-test), reduction of IgA content in the initial period, significant raising of interleukin-6 (IL-6) level on the first postoperative day are characteristic. Quantity of active neutrophils of type II in the blood of patients with CTBD depends on antigenic load. Neutrophils in the bile restore the NBT according to type I. Local concentration of IL-6 and IL-8, and also the functional activity of neutrophils in ductal bile in patients with CTBD are the sensitive indexes of clinical state and immunological reactivity.
authors.forename: M E
authors.initials: ME
authors.lastname: Nichitaĭlo
authors.forename: A A
authors.initials: AA
authors.lastname: Stasenko
authors.forename: A V
authors.initials: AV
authors.lastname: Skums
authors.forename: I P
authors.initials: IP
authors.lastname: Galochka
mesh_terms: D000293:Adolescent; D000328:Adult; D001649:Bile Duct Diseases / Q000276:immunology* / Q000378:metabolism* / Q000601:surgery; D002648:Child; D003560:Cysts / Q000276:immunology* / Q000378:metabolism* / Q000601:surgery; D018450:Disease Progression; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology*; D008297:Male; D009504:Neutrophils / Q000378:metabolism
chemical_list: D007136:Immunoglobulins