Sensorimotor gating: startle submits to presynaptic inhibition.
Prepulse inhibition is a type of sensorimotor gating that is disrupted in some neuropsychiatric disorders. Its cellular basis has eluded investigators but now, using a molluscan model system, a cellular mechanism has been established.
Nusbaum
Michael P
MP
Department of Neuroscience, University of Pennsylvania School of Medicine, 215 Stemmler Hall, Philadelphia, Pennsylvania 19104-6074, USA. nusbaum@mail.med.upenn.edu
Contreras
Diego
D
D000818:Animals; D007395:Interneurons / Q000502:physiology; D008959:Models, Neurological; D009433:Neural Inhibition / Q000502:physiology*; D010812:Physical Stimulation; D013216:Reflex, Startle / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology*; D013997:Time Factors