[Clinical study of cerebral oxygen utilization coefficients in patients with severe head injury].
OBJECTIVE
To investigate the relationship in cerebral oxygen utilization coefficients (O.2UCc) in patients with acute severe head injury and illness prognosis.


METHODS
Forty patients with acute severe head injury were studied, and 40 patients with light head injury were used as control. Through blood analysis, the changes in oxygen saturation of carotid blood (SaO(2)), oxygen saturation of jugular blood (SjO(2)), cerebral arteriovenous difference of oxygen saturation (S(a-j)O(2)), O.2 UCc were observed. Furthermore, the relationship of these patients' condition and prognosis was analyzed.


RESULTS
There was no significant change between the test group and control group in SaO(2). In test group, SjO(2) increased and O.2 UCc decreased, there was an obvious difference between two groups (both P<0.01). In test group, 26 died and 14 lived. There was no significant difference between died and lived patients in SaO(2). SjO(2) significantly increased and O.2 UCc obviously decreased in died patients in comparison with those of the lived patients (both P<0.01).


CONCLUSIONS
Cerebral oxygen metabolism dynamics obstacle frequently was accompanied with acute severe head injury. The high SjO(2) and low O.2 UCc are main symptoms with O.2 UCc<11percent hinting a bad prognosis.
Tian
Hui
H
ICU, Liaocheng People's Hospital, Liaocheng 252000, Shandong, China.
Wu
Tie-jun
TJ
Zhang
Lian-qun
LQ
Tian
Suo-chen
SC
Qu
Ai-jun
AJ
Cai
Xiu-hua
XH
D000328:Adult; D001784:Blood Gas Analysis; D002339:Carotid Arteries / Q000378:metabolism; D006259:Craniocerebral Trauma / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D007601:Jugular Veins / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism*; D011379:Prognosis; D015599:Trauma Severity Indices
D010100:Oxygen