title: Prostate gland-like epithelium in the epididymis: a case report and review of the literature.
abstract: Aberrant prostatic tissue occurs commonly in the adult male urethra and bladder. Ectopic prostatic tissue occurring outside the urinary system is rare. One case with scattered prostate-type glands in epididymis has been reported in the literature. We report a related case, in which the presence of prostate gland-like epithelium was recognized in epididymal glands in routine histology and was confirmed by subsequent immunohistochemical analysis using prostate-specific antigen. We then examined 23 additional orchiectomy specimens for the presence of prostate-like epithelium. The possibility of this being true ectopia versus an unusual metaplastic change is discussed.
authors.affiliation: Department of Pathology, Mount Sinai Medical Center, New York, NY, USA. leeli@nychhc.org
authors.forename: Lisa Yan-Jie
authors.initials: LY
authors.lastname: Lee
authors.forename: James
authors.initials: J
authors.lastname: Tzeng
authors.forename: Marina
authors.initials: M
authors.lastname: Grosman
authors.forename: Pamela D
authors.initials: PD
authors.lastname: Unger
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers; D002648:Child; D002675:Child, Preschool; D002828:Choristoma / Q000473:pathology*; D003456:Cryptorchidism / Q000601:surgery; D004822:Epididymis / Q000473:pathology*; D004848:Epithelium / Q000648:ultrastructure; D006552:Hernia, Inguinal / Q000601:surgery; D006801:Humans; D033162:Incidental Findings; D008297:Male; D008679:Metaplasia; D008875:Middle Aged; D009919:Orchiectomy; D011467:Prostate / Q000737:chemistry; D017430:Prostate-Specific Antigen / Q000032:analysis; D012189:Retrospective Studies; D013733:Testicular Diseases / Q000473:pathology*; D013736:Testicular Neoplasms / Q000601:surgery
chemical_list: D015415:Biomarkers; D017430:Prostate-Specific Antigen