title: [Current data on interferon therapy of multiple sclerosis in patients at developmental age].
abstract: Multiple sclerosis (MS) is a rare disorder of the central nervous system in children. In spite of the investigations of the last decade its etiology has not been established. The authors of the paper presented data on the specific nature of children MS using the current literature. They also demonstrated the role of interferon (INF) and clinical trials of MS treatment in children. The authors described their own experiences in the treatment of a boy with the youth MS using INF. The patient has suffered from MS since he was 15; INF therapy was introduced after two relapses of the disease. The results of the 18-month therapy with INF suggest beneficial immunomodulatory effects of interferon on MS course in children. The presented patient is continuing the therapy while his clinical status is being observed.
authors.affiliation: Klinika Neurologii Dzieciecej, Akademia Medyczno, ul. Waszyngtona 17, 15-354 Białystok.
authors.forename: Joanna
authors.initials: J
authors.lastname: Smigielska-Kuzia
authors.forename: Wojciech
authors.initials: W
authors.lastname: Sobaniec
authors.forename: Wojciech
authors.initials: W
authors.lastname: Kułak
authors.forename: Leszek
authors.initials: L
authors.lastname: Boćkowski
authors.forename: Marzanna
authors.initials: M
authors.lastname: Wołk
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Sołowiej
authors.forename: Barbara
authors.initials: B
authors.lastname: Artemowicz
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D001921:Brain / Q000473:pathology*; D002648:Child; D005073:Evoked Potentials, Somatosensory / Q000502:physiology; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*; D016899:Interferon-beta / Q000627:therapeutic use*; D009103:Multiple Sclerosis / Q000188:drug therapy* / Q000473:pathology* / Q000503:physiopathology
chemical_list: D000276:Adjuvants, Immunologic; D016898:Interferon-alpha; D016899:Interferon-beta