[Effect of nocturnal hypoxaemia on the development of pulmonary hypertension in patients with COPD].
Majority of subjects with severe COPD develop mild pulmonary hypertension. Those patients usually present with diurnal, resting hypoxaemia. Further hypoxaemic dips during sleep probably contribute to development permanent pulmonary hypertension. However, separation of effects of diurnal from nocturnal hypoxaemia is difficult. Correlations between severity of nocturnal hypoxaemia and pulmonary arterial pressure and pulmonary vascular resistance were week. There was no correlation between time spent in desaturation and pulmonary arterial pressure and pulmonary resistance.
Hawryłkiewicz
Iwona
I
II Klinika Chorób Płuc, Instytut Gruźlicy i Chorób Płuc, Warszawa.
Górecka
Dorota
D
Pływaczewski
Robert
R
Sliwiński
Paweł
P
Zieliński
Jan
J
D000328:Adult; D003251:Constriction, Pathologic / Q000209:etiology; D005260:Female; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology* / Q000503:physiopathology; D000860:Hypoxia / Q000150:complications* / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D011652:Pulmonary Circulation; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000503:physiopathology*; D012307:Risk Factors; D012891:Sleep Apnea Syndromes / Q000209:etiology* / Q000503:physiopathology; D013147:Spirometry; D013997:Time Factors
D010100:Oxygen