title: High variety of different simian T-cell leukemia virus type 1 strains in chimpanzees (Pan troglodytes verus) of the Taï National Park, Côte d'Ivoire.
abstract: We found human T-cell leukemia virus type 1- and simian T-cell leukemia virus type 1 (STLV-1)-related infections in 5 of 10 chimpanzees originating from three groups of wild chimpanzees. The new virus isolates showed a surprising heterogeneity not only in comparison to STLV-1 described previously in other primate species but also between the different chimpanzee groups, within a group, or even between strains isolated from an individual animal. The interdisciplinary combination of virology, molecular epidemiology, and long-term behavioral studies suggests that the primary route of infection might be interspecies transmission from other primates, such as red colobus monkeys, that are hunted and consumed by chimpanzees.
authors.affiliation: Division of Retrovirology, Robert Koch Institute, D-13353 Berlin, Germany.
authors.forename: Fabian H
authors.initials: FH
authors.lastname: Leendertz
authors.forename: Sandra
authors.initials: S
authors.lastname: Junglen
authors.forename: Christophe
authors.initials: C
authors.lastname: Boesch
authors.forename: Pierre
authors.initials: P
authors.lastname: Formenty
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Couacy-Hymann
authors.forename: Valerie
authors.initials: V
authors.lastname: Courgnaud
authors.forename: Georg
authors.initials: G
authors.lastname: Pauli
authors.forename: Heinz
authors.initials: H
authors.lastname: Ellerbrok
mesh_terms: D000818:Animals; D000835:Animals, Wild / Q000821:virology; D018420:Ape Diseases / Q000635:transmission / Q000821:virology*; D001483:Base Sequence; D003104:Colobus / Q000821:virology; D007560:Cote d'Ivoire; D004279:DNA, Viral / Q000235:genetics; D006800:Deltaretrovirus Infections / Q000635:transmission / Q000662:veterinary / Q000821:virology; D019143:Evolution, Molecular; D005260:Female; D014644:Genetic Variation; D015490:HTLV-I Infections / Q000635:transmission / Q000662:veterinary / Q000821:virology; D015368:Human T-lymphotropic virus 1 / Q000235:genetics / Q000302:isolation & purification; D008297:Male; D002679:Pan troglodytes / Q000821:virology*; D010802:Phylogeny; D015303:Simian T-lymphotropic virus 1 / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification* / Q000472:pathogenicity; D013045:Species Specificity
chemical_list: D004279:DNA, Viral