title: A patient with hyper-IgD syndrome in Antalya, Turkey.
abstract: Hyper-IgD syndrome is a periodic fever syndrome that presents with recurrent episodes of high fever accompanied by lymphadenopathy, abdominal distress, arthralgias or arthritis, headache and skin lesions. The diagnosis is based on clinical grounds and elevated serum IgD levels (>100 U/ml), but requires a high index of suspicion, and a mevalonate kinase enzyme defect. Most patients are from western Europe but there are others identified in other countries. We describe a 17-year-old patient who had been followed with the diagnosis of familial Mediterranean fever for a long time before she was diagnosed with hyper-IgD syndrome.
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, Akdeniz University, Arapsuyu, 07070, Antalya, Turkey. ecoban@akdeniz.edu.tr
authors.forename: Erkan
authors.initials: E
authors.lastname: Coban
authors.forename: Ender
authors.initials: E
authors.lastname: Terzioğlu
mesh_terms: D000293:Adolescent; D003937:Diagnosis, Differential; D010505:Familial Mediterranean Fever / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007072:Immunoglobulin D / Q000097:blood*; D007589:Job Syndrome / Q000097:blood* / Q000175:diagnosis*; D014421:Turkey
chemical_list: D007072:Immunoglobulin D