title: [Current concepts and recent developments of laser ablation in tumor therapy].
abstract: OBJECTIVE
  The purpose of this paper is to present technical innovations and clinical results of percutaneous interventional laser ablation of tumors using new techniques. METHODS; Laser ablation was performed in 182 patients (liver tumors: 131, non hepatic tumors-bone, lung, others: 51) after interdisciplinary consensus was obtained. The procedure was done using a combination of imaging modalities (CT/MRI, CT/US) or only closed high field MRI (1.5 T). All patients received an MRI-scan immediately after laser ablation.
  
  
  RESULTS
  In 90.9% of the patients with liver tumors, a complete ablation was achieved. Major events occurred in 5.4%. The technical success rate of laser ablation in non-hepatic tumors was high, clinical results differed depending on the treated organ.
  
  
  CONCLUSIONS
  The treatment of tumors of the liver and other organs up to 5 cm by laser ablation was a safe procedure with a low rate of complications and side effects. Image guidance by MRI is advantageous for precise tumor visualization in all dimensions, therapy monitoring, and control of laser ablation results.
authors.affiliation: Klinik für Strahlenheilkunde der Charité, Campus-Virchow-Klinikum und Campus Buch-Medizinische Fakultät der Humboldt-Universität zu Berlin. stros@charite.de
authors.forename: C
authors.initials: C
authors.lastname: Stroszczynski
authors.forename: G
authors.initials: G
authors.lastname: Gaffke
authors.forename: M
authors.initials: M
authors.lastname: Gnauck
authors.forename: R
authors.initials: R
authors.lastname: Puls
authors.forename: N
authors.initials: N
authors.lastname: Hosten
authors.forename: U
authors.initials: U
authors.lastname: Speck
authors.forename: J
authors.initials: J
authors.lastname: Ricke
authors.forename: H
authors.initials: H
authors.lastname: Oettle
authors.forename: P
authors.initials: P
authors.lastname: Hohenberger
authors.forename: R
authors.initials: R
authors.lastname: Felix
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods* / Q000639:trends; D053685:Laser Therapy / Q000379:methods* / Q000639:trends; D008113:Liver Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000628:therapy*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000628:therapy; D009928:Organ Specificity; D013813:Therapy, Computer-Assisted / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome; D014463:Ultrasonography / Q000379:methods*