Drosophila as an emerging model to study metastasis.
Metastasis is the primary cause of human cancer-related deaths. Two recent studies describe a system for testing how multiple genetic events synergize to promote neoplastic growth and metastasis in Drosophila, paving the way for systematic approaches to understanding metastasis using the powerful tools of Drosophila genetics.
Kango-Singh
Madhuri
M
Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
Halder
Georg
G
D000818:Animals; D004195:Disease Models, Animal; D004330:Drosophila / Q000235:genetics*; D006801:Humans; D009362:Neoplasm Metastasis / Q000235:genetics*; D009374:Neoplasms, Experimental / Q000235:genetics