[Induction of mutations in unirradiated X-chromosome of Drosophila melanogaster hybrids of repair deficient females mei-41 [D5] and mus209 [B1] and irradiated males M5].
It has been analyzed the frequency of the recessive lethal mutations in the unirradiated X-chromosome of Drosophila. Females of wild type (CS) as well as of error-prone (mei-41) and error-free (mus209) mutant strains were used. In CS hybrids the increasing of the mutation rate (p < 0.05) was found. In muc209 hybrids the mutation rate was not affected. In mei-41 hybrids the tendency to decreasing of the mutation rate was found. The obtained results demonstrate the possible role of error-prone repair in the inducing of mutations in the unirradiated X-chromosome in the presence of irradiated homologue.
Shaposhnikov
M V
MV
Institute of Biology Ural Division, Russian Academy of Sciences, Syktyvkar, 167982 Russia. shaposhnikov@ib.komisc.ru
Zaĭnullin
V G
VG
Belogolov
I N
IN
D000818:Animals; D004260:DNA Repair; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D005804:Genes, Lethal; D005808:Genes, Recessive; D005838:Genotype; D008297:Male; D016296:Mutagenesis; D009154:Mutation; D011829:Radiation Dosage; D014960:X Chromosome / Q000528:radiation effects*