title: Advances in the study of luminescence probes for proteins.
abstract: Spectral probes (or labels) have been widely used for the investigation and determination of proteins and have made considerable progress. Traditional luminescence probes include fluorescent derivatizing reagents, fluorescent probes and chemiluminescence probes which continue to develop. Of them, near infrared (NIR) fluorescent probes are especially suitable for the determination of biomolecules including proteins, so their development has been rapid. Novel luminescence probes (such as nanoparticle probes and molecular beacons) and resonance light scattering probes recently appeared in the literature. Preliminary results indicate that they possess great potential for ultrasensitive protein detection. This review summarizes recent developments of the above-mentioned probes for proteins and 195 references are cited.
authors.affiliation: Key Laboratory for Colloid and Interface Chemistry of Education Ministry, Department of Chemistry, Shandong University, Jinan 250100, PR China.
authors.forename: Changxia
authors.initials: C
authors.lastname: Sun
authors.forename: Jinghe
authors.initials: J
authors.lastname: Yang
authors.forename: Lei
authors.initials: L
authors.lastname: Li
authors.forename: Xia
authors.initials: X
authors.lastname: Wu
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.forename: Shufang
authors.initials: S
authors.lastname: Liu
mesh_terms: D008163:Luminescent Measurements; D015335:Molecular Probes; D011506:Proteins / Q000737:chemistry*
chemical_list: D015335:Molecular Probes; D011506:Proteins