title: [Sertraline and acute pancreatitis: a case-report].
abstract: Acute pancreatitis is a severe disease with considerable morbidity and mortality. Many risk factors are causally related to acute pancreatitis. In this report, a case of acute pancreatitis with possible causal relationship with the use of a selective serotonin reuptake inhibitor, sertraline, will be discussed. After one month of treatment with sertraline, a female patient, 55 years-old, developed a severe abdominal pain and showed a serum amylase elevation. She was admitted to the hospital and the use of sertraline was interrupted. After that, the symptoms remitted and the serum amylase level returned to normal. Because of the potential severity of this disease and the widespread use of sertraline, this association should be reminded when investigating possible causes for acute pancreatitis.
authors.affiliation: Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil. amalbergier@uol.com.br
authors.forename: André
authors.initials: A
authors.lastname: Malbergier
authors.forename: Hercílio Pereira
authors.initials: HP
authors.lastname: de Oliveira Júnior
mesh_terms: D000208:Acute Disease; D003863:Depression / Q000188:drug therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D010195:Pancreatitis / Q000139:chemically induced*; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects*; D020280:Sertraline / Q000009:adverse effects*
chemical_list: D017367:Selective Serotonin Reuptake Inhibitors; D020280:Sertraline