title: Acute myeloblastic leukemia in pregnancy: a case report and review of the literature.
abstract: Leukemia is a rare event during pregnancy. The presence of leukemia during pregnancy raises several concerns about the effect of pregnancy on the prognosis of leukemia, the effect of the disease on pregnancy outcome and the teratogenic and mutagenic effect of chemotherapeutic agents on the fetus. We report a case of acute myeloblastic leukemia diagnosed during the third trimester of gestation and treated with chemotherapeutic agents before delivery. The duration of pregnancy was able to be prolonged for four weeks after clinical diagnosis of the disease and then terminated by cesarean section due to the presence of signs of fetal distress.
authors.affiliation: Department of Obstetrics and Gynecology, Ege University Facultè of Medicine, Izmir, Turkey.
authors.forename: M S
authors.initials: MS
authors.lastname: Yucebilgin
authors.forename: S
authors.initials: S
authors.lastname: Cagirgan
authors.forename: A
authors.initials: A
authors.lastname: Donmez
authors.forename: E
authors.initials: E
authors.lastname: Ozkinay
authors.forename: F
authors.initials: F
authors.lastname: Akercan
authors.forename: L
authors.initials: L
authors.lastname: Mgoyi
authors.forename: F
authors.initials: F
authors.lastname: Vural
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003561:Cytarabine / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D015255:Idarubicin / Q000008:administration & dosage; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis* / Q000188:drug therapy; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000188:drug therapy; D011263:Pregnancy Trimester, Third
chemical_list: D003561:Cytarabine; D015255:Idarubicin