Use of an immunoglobulin G avidity test to discriminate between primary and secondary dengue virus infections.
An enzyme-linked immunosorbent assay-based immunoglobulin G (IgG) antibody avidity test was evaluated by using sera from 57 patients with acute dengue infection. Overall, 55 of 57 patients were correctly classified (27 of 27 with primary dengue and 28 of 30 with secondary dengue). We conclude that the IgG avidity test can be useful for differentiating between acute, primary, and secondary dengue infections.
de Souza
Vanda Akico Ueda Fick
VA
Laboratório de Virologia (LIMHC-52), Instituto de Medicina Tropical de São Paulo, Brazil.
Fernandes
Silvana
S
Araújo
Evaldo Stanislau
ES
Tateno
Adriana Fumie
AF
Oliveira
Olímpia M N P F
OM
Oliveira
Renato Reis
RR
Pannuti
Cláudio Sérgio
CS
D000208:Acute Disease; D000914:Antibodies, Viral / Q000097:blood / Q000276:immunology*; D000915:Antibody Affinity; D002908:Chronic Disease; D003715:Dengue / Q000175:diagnosis* / Q000276:immunology; D003716:Dengue Virus / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology*
D000914:Antibodies, Viral; D007074:Immunoglobulin G