[Comparative research of the donor site wound healing in occlusive and dry environments].
OBJECTIVE
To compare and research the process of wound healing in occlusive moist environment and dry environment on the skin donor site.


METHODS
The wound healing of adult skin donor site was studied by clinical observation, histological and electromicroscopical examinations on the operative day and the 1st, 2nd, 3rd, 4th, 7th days postoperatively, each skin donor site was divided into two parts: occlusive environment and dry environment.


RESULTS
The wounds of occlusive moist environment healed faster than those of dry environment; the fibroblasts were more active and activated earlier, revascularization and re-epithelialization happened earlier and more quickly.


CONCLUSIONS
In occlusive environment, more active fibroblasts can accelerate granulation growth; quicker regenerative capillaries bring more nourishment; quicker re-epithelialization accelerates the wound healing.
Zhang
Jie
J
Department of Plastic Surgery, Third Hospital of Peking University, Beijing, P. R. China 100083.
Niu
Xing-tao
XT
Li
Dong
D
D000328:Adult; D002455:Cell Division; D004848:Epithelium / Q000648:ultrastructure; D005260:Female; D005347:Fibroblasts / Q000502:physiology / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008875:Middle Aged; D018919:Neovascularization, Physiologic / Q000187:drug effects; D009779:Occlusive Dressings; D012867:Skin / Q000098:blood supply / Q000648:ultrastructure; D016038:Skin Transplantation; D014945:Wound Healing / Q000187:drug effects* / Q000502:physiology