title: Meningitis due to Haemophilus influenzae type f in an 8-year-old girl with congenital humoral immunodeficiency.
abstract: We report on an 8-year-old Haemophilus influenzae type b-vaccinated girl with meningitis due to H. influenzae type f. The girl had an oro-facio-digital syndrome and a hypogammaglobulinemia, obviously predisposing the patient to invasive infections. Treatment with cefotaxime was successful.Incidence, predisposing factors and the influence of H. influenzae type b immunization on invasive infections with non-type b H. influenzae strains in children are discussed.
authors.affiliation: Institute for Medical Microbiology and Epidemiology of Infectious Diseases, University of Leipzig, Liebigstrasse 24, D-04103, Leipzig, Germany. fiwe@medizin.uni-leipzig.de
authors.forename: K
authors.initials: K
authors.lastname: Fickweiler
authors.forename: M
authors.initials: M
authors.lastname: Borte
authors.forename: M
authors.initials: M
authors.lastname: Fasshauer
authors.forename: F-B
authors.initials: FB
authors.lastname: Spencker
authors.forename: W
authors.initials: W
authors.lastname: Handrick
authors.forename: A C
authors.initials: AC
authors.lastname: Rodloff
mesh_terms: D000900:Anti-Bacterial Agents; D002648:Child; D004359:Drug Therapy, Combination / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D006193:Haemophilus influenzae / Q000302:isolation & purification*; D006801:Humans; D016867:Immunocompromised Host; D007153:Immunologic Deficiency Syndromes / Q000151:congenital* / Q000276:immunology; D008583:Meningitis, Haemophilus / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology*; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents