The correlation between plasma homocysteine and malondialdehyde levels in preeclampsia.
OBJECTIVE
To investigate the possible correlation between plasma malondialdehyde and homocysteine levels of preeclamptic patients.


METHODS
Venous blood samples of 20 preeclamptics and 20 healthy pregnant controls were collected. Plasma malondialdehyde and homocysteine concentrations were measured and the correlation between them was investigated. Mann Whitney U test and Spearman correlation analysis were used for statistical analysis.


METHODS
University of Firat, Medical School.


RESULTS
Plasma malondialdehyde and homocysteine concentrations were higher in preeclamptic patients (p<0.05) and a positive correlation between these parameters was found (r: 0.77, p<0.01, n:20).


CONCLUSIONS
Our results may put forward some new strategies in the research of etiopathogenesis and treatment of preeclampsia.
Tug
Niyazi
N
Obstetrics and Gynecology Department, Firat University School of Medicine, Elazig, Turkey.
Celik
Husnu
H
Cikim
Gurkan
G
Ozcelik
Oguz
O
Ayar
Ahmet
A
D000328:Adult; D005260:Female; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D015227:Lipid Peroxidation; D008054:Lipid Peroxides / Q000378:metabolism; D008315:Malondialdehyde / Q000097:blood*; D011225:Pre-Eclampsia / Q000097:blood* / Q000209:etiology*; D011247:Pregnancy; D012720:Severity of Illness Index
D008054:Lipid Peroxides; D006710:Homocysteine; D008315:Malondialdehyde