Oligohydramnios and fetal renal sonographic appearances related to prostaglandin synthetase inhibitors. A case report.
A case of acute neonatal renal failure in twins following tocolytic treatment with ketoprotene is described. The twins had visible signs in utero of developed anhydramniosis associated with morphological renal abnormalities on ultrasound. At birth both twins had acute renal failure with reduced creatinine and urea levels, which could only be normalized after 3 and 18 months, respectively.
Fieni
S
S
Department of Gynecology, Obstetrics and Neonatology, University of Parma, Parma, Italy.
Gramellini
D
D
Vadora
E
E
D058186:Acute Kidney Injury / Q000097:blood / Q000139:chemically induced; D000328:Adult; D003404:Creatinine / Q000097:blood; D016861:Cyclooxygenase Inhibitors / Q000009:adverse effects*; D004200:Diseases in Twins; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007660:Ketoprofen / Q000009:adverse effects*; D007668:Kidney / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000196:embryology*; D016104:Oligohydramnios / Q000139:chemically induced*; D011247:Pregnancy; D015149:Tocolytic Agents / Q000009:adverse effects*; D016216:Ultrasonography, Prenatal; D014508:Urea / Q000097:blood
D016861:Cyclooxygenase Inhibitors; D015149:Tocolytic Agents; D014508:Urea; D007660:Ketoprofen; D003404:Creatinine