Chemoprevention by 1,2-dithiole-3-thiones through induction of NQO1 and other phase 2 enzymes.
Kwak
Mi-Kyoung
MK
Department of Environmental Health Sciences, School of Public Health Sciences, Johns Hopkins University Bloomberg, Baltimore, Maryland 21205, USA.
Ramos-Gomez
Minerva
M
Wakabayashi
Nobunao
N
Kensler
Thomas W
TW
D000818:Animals; D016588:Anticarcinogenic Agents / Q000737:chemistry / Q000494:pharmacology*; D002352:Carrier Proteins / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000172:deficiency / Q000235:genetics / Q000378:metabolism; D004790:Enzyme Induction / Q000187:drug effects; D006801:Humans; D016660:NAD(P)H Dehydrogenase (Quinone) / Q000096:biosynthesis* / Q000378:metabolism; D051267:NF-E2-Related Factor 2; D013438:Sulfhydryl Compounds / Q000737:chemistry / Q000494:pharmacology*; D013871:Thiones / Q000737:chemistry / Q000494:pharmacology*; D015534:Trans-Activators / Q000172:deficiency / Q000235:genetics / Q000378:metabolism
D016588:Anticarcinogenic Agents; D002352:Carrier Proteins; D004268:DNA-Binding Proteins; D051267:NF-E2-Related Factor 2; C495635:NFE2L2 protein, human; D013438:Sulfhydryl Compounds; D013871:Thiones; D015534:Trans-Activators; D016660:NAD(P)H Dehydrogenase (Quinone)