title: [Clinical-parasitological response to treatment with quinine associated to doxycycline in uncomplicated falciparum malaria].
abstract: The response of patients with uncomplicated falciparum malaria to quinine plus doxycycline was studied in an open clinical trial. The majority (76.2%; n = 16) had plasmodia sensitive to the treatment and 23.8% (n = 5) were resistant. This therapeutic scheme appears to be a good option in uncomplicated falciparum malaria.
authors.affiliation: Hospital Dr. Manoel Marinho Monte (Plácido de Castro, AC) da Secretaria de Estado de Saúde do Acre, Rio Branco, AC. ms.osvaldo@ac.gov.br
authors.forename: Osvaldo
authors.initials: O
authors.lastname: Leal
authors.forename: Elaine Azevedo Soares
authors.initials: EA
authors.lastname: Leal
authors.forename: Franklin Roberto Pereira
authors.initials: FR
authors.lastname: Borges Júnior
authors.forename: Maria Luiza Torres
authors.initials: ML
authors.lastname: Paez
authors.forename: Sebastião
authors.initials: S
authors.lastname: Teodósio
authors.forename: José
authors.initials: J
authors.lastname: Tavares-Neto
mesh_terms: D000293:Adolescent; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D002648:Child; D004318:Doxycycline / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D016778:Malaria, Falciparum / Q000188:drug therapy*; D010963:Plasmodium falciparum / Q000187:drug effects; D011803:Quinine / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000962:Antimalarials; D011803:Quinine; D004318:Doxycycline