[The condition of the antioxidant system and lipid peroxidation in victims with a severe compound trauma].
The study was made of lipid peroxidation (LPO) and antioxidant system (AOS) in 50 victims with a severe compound trauma regarding the patients' condition assessed by APACHE II scale at admission to a critical care unit. It is shown that disorders in the system LPO-AOS depend on severity of the trauma and manifest most obviously in most severe trauma, therefore the degree of LPO-AOS imbalance is a significantly informative criterion of pathobiochemical disturbances. The coefficient K, the indicator of imbalance in the system LPO-AOS, is proposed as a pathogenetically sound criterion of the assessment of the patient's condition severity in the victims with a severe compound trauma.
Kartavenko
V I
VI
Golikov
P P
PP
Davydov
B V
BV
Andreev
A A
AA
D000975:Antioxidants / Q000378:metabolism*; D002570:Ceruloplasmin / Q000378:metabolism; D006801:Humans; D015601:Injury Severity Score; D015227:Lipid Peroxidation; D008315:Malondialdehyde / Q000097:blood; D009104:Multiple Trauma / Q000097:blood* / Q000503:physiopathology*; D012016:Reference Values; D024502:alpha-Tocopherol / Q000097:blood
D000975:Antioxidants; D008315:Malondialdehyde; D002570:Ceruloplasmin; D024502:alpha-Tocopherol