title: Graves' ophthalmopathy evolution studied by MRI during childhood and adolescence.
abstract: Pediatric patients with Graves' disease (n=26) were studied longitudinally by magnetic resonance imaging of the orbits, allowing an assessment of the enlargement of the extraocular muscles and orbital volume variations. The positive outcome of Graves' ophthalmopathy correlated with low TRAb (autoantibodies to thyroid-stimulating hormone receptor) titers at diagnosis and during follow-up and with prepubertal condition at diagnosis.
authors.affiliation: Pediatric Clinic and Radiology Department, Policlinico Giambattista Rossi, University of Verona, Piazza Ludovico Antonio Scuro 10, I-37134 Verona, Italy. franco.antoniazzi@univr.it
authors.forename: Franco
authors.initials: F
authors.lastname: Antoniazzi
authors.forename: Giorgio
authors.initials: G
authors.lastname: Zamboni
authors.forename: Roberto
authors.initials: R
authors.lastname: Cerini
authors.forename: Silvana
authors.initials: S
authors.lastname: Lauriola
authors.forename: Alberto
authors.initials: A
authors.lastname: Dall'Agnola
authors.forename: Luciano
authors.initials: L
authors.lastname: Tatò
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D018450:Disease Progression; D005094:Exophthalmos / Q000473:pathology; D005260:Female; D006111:Graves Disease / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging; D008297:Male; D009801:Oculomotor Muscles / Q000254:growth & development / Q000473:pathology; D009915:Orbit / Q000254:growth & development / Q000473:pathology*; D011627:Puberty / Q000502:physiology; D011989:Receptors, Thyrotropin / Q000097:blood; D012016:Reference Values
chemical_list: D011989:Receptors, Thyrotropin