title: [Estimation of quantitative proteinuria using a new dipstick in random urine samples].
abstract: Proteinuria is quantified for diagnostic and prognostic purposes and to assess responses to therapy. Methods used to assess urinary protein include 24-hour urine collection (24-Up) and determination of the ratio of protein to creatinine concentration (Up/Ucr) in simple voided urine samples (Up/Ucr quantitative method). However, these methods are costly and time consuming. The Multistix PRO 11 (Bayer Medical Co., Ltd., Tokyo, Japan) is a new urine dipstick that allows rapid measurement of Up/Ucr. Results obtained with the Multistix PRO 11 coincided well with those obtained with the 24-Up method (kappa = 0.68) and the Up/Ucr quantitative method (kappa = 0.75). However, Multistix PRO 11 did not accurately measure moderate to severe proteinuria (> or = 500 mg/g. Cr). Our findings suggest that Multistix PRO 11 is useful for the screening, assessment, and follow-up of mild proteinuria.
authors.affiliation: Department of Nephrology, Jichi Medical School, Tochigi, Japan.
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Morishita
authors.forename: Eiji
authors.initials: E
authors.lastname: Kusano
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Umino
authors.forename: Jun
authors.initials: J
authors.lastname: Nemoto
authors.forename: Kaichirou
authors.initials: K
authors.lastname: Tanba
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Ando
authors.forename: Shigeaki
authors.initials: S
authors.lastname: Muto
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Asano
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002940:Circadian Rhythm; D003404:Creatinine / Q000652:urine*; D005260:Female; D006801:Humans; D007677:Kidney Function Tests / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011507:Proteinuria / Q000175:diagnosis* / Q000652:urine; D011934:Reagent Strips; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index
chemical_list: D011934:Reagent Strips; D003404:Creatinine