title: Cognitive impairment in substance abuse.
abstract: Conventional wisdom, and even well-reasoned theoretical mechanisms, suggests that the chronic use of psychoactive substances would impair cognitive functioning of individuals. This article summarizes the research literature with regard to specific drugs of abuse. Undoubtedly, acute intoxication and immediate and protracted withdrawal produce transient alterations of cognitions that can persist for weeks to months. Some subtle residual effects remain for up to 1 year for certain drugs. Evidence of irreversible effects is less clear. Even subtle lingering effects can impact treatment efforts, yet they often go undetected or unaddressed.
authors.affiliation: Department of Psychology, Idaho State University, Box 8112, Pocatello, ID 83209, USA. vikpete@isu.edu
authors.forename: Peter W
authors.initials: PW
authors.lastname: Vik
authors.forename: Tony
authors.initials: T
authors.lastname: Cellucci
authors.forename: Amy
authors.initials: A
authors.lastname: Jarchow
authors.forename: Jill
authors.initials: J
authors.lastname: Hedt
mesh_terms: D000425:Alcohol Amnestic Disorder / Q000150:complications; D000662:Amphetamines / Q000009:adverse effects; D000697:Central Nervous System Stimulants / Q000009:adverse effects; D003072:Cognition Disorders / Q000139:chemically induced / Q000453:epidemiology*; D000431:Ethanol / Q000009:adverse effects*; D006801:Humans; D002189:Marijuana Abuse / Q000453:epidemiology; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000009:adverse effects; D019966:Substance-Related Disorders / Q000453:epidemiology*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
chemical_list: D000662:Amphetamines; D000697:Central Nervous System Stimulants; D000431:Ethanol; D005680:gamma-Aminobutyric Acid; D018817:N-Methyl-3,4-methylenedioxyamphetamine