In vivo confocal microscopic findings in patients with steroid-induced glaucoma after LASIK.
OBJECTIVE
To report the confocal microscopic findings of 2 different cases of steroid-induced glaucoma after LASIK.


METHODS
Observational case report of 2 cases.


METHODS
Two cases of steroid-induced glaucoma after LASIK were selected. Examination with a white-light tandem slit-scanning confocal microscope was performed in addition to routine slit-lamp biomicroscopy.


METHODS
In vivo confocal findings at the flap interface.


RESULTS
In both cases, the interfaces were identified at a deeper level than expected. Confocal microscopic examination did not show mononuclear cells and granulocytes typically seen in patients with classic diffuse lamellar keratitis.


CONCLUSIONS
Our findings confirm that steroid-induced glaucoma after LASIK is not associated with the collection of inflammatory cells. The treatment option of lowering the intraocular pressure is effective in treating the disease, even without anti-inflammatory medications. Confocal in vivo microscopy is a useful tool to study the course of steroid-induced glaucoma after LASIK in humans.
Cheng
Arthur C K
AC
Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, 3F, Hong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong Kong, China. arthurcheng@cuhk.edu.hk
Law
Ricky W K
RW
Young
Alvin L
AL
Lam
Dennis S C
DS
D000328:Adult; D003315:Cornea / Q000473:pathology; D005260:Female; D005901:Glaucoma / Q000139:chemically induced* / Q000175:diagnosis*; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D007429:Intraocular Pressure; D007634:Keratitis / Q000175:diagnosis / Q000188:drug therapy; D020731:Keratomileusis, Laser In Situ; D018613:Microscopy, Confocal; D011183:Postoperative Complications; D011239:Prednisolone / Q000009:adverse effects* / Q000031:analogs & derivatives*; D014794:Visual Fields
D005938:Glucocorticoids; C009935:prednisolone acetate; D011239:Prednisolone