[The content of estradiol receptors in oral mucosa precancerous lesions and its effect]
OBJECTIVE:In order to clarify the content of estroen receptors (ER) in oral mucosa precancerous lesions and its effect on dignosis and treatment. METHODS: ER was measured by SP method in 19oral squamous cell carcinoma (SCC),20 oral leukoplakia(LK),21 oral lichen planus (LP) and 7 normal mucosa(NM). RESULTS: 42.86%,71.43%,60.00%,68.42% were ER positive in NM,LP,LK,SCC respectively. The postitive cells located in spinous layer.ER contents were no significance different in these four diseases.There was no relationship between ER content and pathologic staging. CONCLUSION: It showed that ER existed in SCC,LK,LP and NM,but it could not implicate for the carcinogenesis.Oral mucousal tumor is perhaps hormone depended.
Yao
H
H
Department of Oral Medicine, First Affiliated Hospital, Zhejiang Medical University. Zhejiang 310009,China.
Wu
B X
BX