Genetic networks in the early development of Caenorhabditis elegans.
One of the best-studied model organisms in biology is Caenorhabditis elegans. Because of its simple architecture and other biological advantages, considerable data have been collected about the regulation of its development. In this review, currently available data concerning the early phase of embryonic development are presented in the form of genetic networks. We performed computer simulations of regulatory mechanisms in embryonic development, and the results are described and compared with experimental observations.
Platzer
Ute
U
Division Medical and Biological Informatics, Deutsches Krebsforschungszentrum D-69120 Heidelberg, Germany.
Meinzer
Hans-Peter
HP
D000818:Animals; D001757:Blastomeres / Q000166:cytology / Q000378:metabolism; D019521:Body Patterning / Q000235:genetics; D017173:Caenorhabditis elegans / Q000166:cytology / Q000196:embryology* / Q000235:genetics*; D002454:Cell Differentiation / Q000235:genetics*; D019070:Cell Lineage / Q000235:genetics*; D003198:Computer Simulation; D004625:Embryo, Nonmammalian / Q000166:cytology / Q000196:embryology* / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental / Q000235:genetics*