[Estimation of quantitative proteinuria using a new dipstick in random urine samples].
Proteinuria is quantified for diagnostic and prognostic purposes and to assess responses to therapy. Methods used to assess urinary protein include 24-hour urine collection (24-Up) and determination of the ratio of protein to creatinine concentration (Up/Ucr) in simple voided urine samples (Up/Ucr quantitative method). However, these methods are costly and time consuming. The Multistix PRO 11 (Bayer Medical Co., Ltd., Tokyo, Japan) is a new urine dipstick that allows rapid measurement of Up/Ucr. Results obtained with the Multistix PRO 11 coincided well with those obtained with the 24-Up method (kappa = 0.68) and the Up/Ucr quantitative method (kappa = 0.75). However, Multistix PRO 11 did not accurately measure moderate to severe proteinuria (> or = 500 mg/g. Cr). Our findings suggest that Multistix PRO 11 is useful for the screening, assessment, and follow-up of mild proteinuria.
Morishita
Yoshiyuki
Y
Department of Nephrology, Jichi Medical School, Tochigi, Japan.
Kusano
Eiji
E
Umino
Tetsuo
T
Nemoto
Jun
J
Tanba
Kaichirou
K
Ando
Yasuhiro
Y
Muto
Shigeaki
S
Asano
Yasushi
Y
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002940:Circadian Rhythm; D003404:Creatinine / Q000652:urine*; D005260:Female; D006801:Humans; D007677:Kidney Function Tests / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011507:Proteinuria / Q000175:diagnosis* / Q000652:urine; D011934:Reagent Strips; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index
D011934:Reagent Strips; D003404:Creatinine