title: Composite metastatic carcinoma in lymph nodes of patients with concurrent medullary and papillary thyroid carcinoma: a report of two cases.
abstract: Synchronous occurrence of medullary and papillary carcinoma of the thyroid gland is very rare. We describe two cases of synchronous medullary and papillary carcinoma of the thyroid. In both cases, medullary carcinoma and papillary carcinoma were separate in the thyroid but mixed in some of the lymph node metastases. A review of the literature and our own cases revealed that composite medullary and papillary carcinoma metastases in the lymph nodes is a common feature of patients with synchronous medullary and papillary carcinoma of the thyroid gland.
authors.affiliation: Keio University School of Medicine, Tokyo, Japan.
authors.forename: Tomohisa
authors.initials: T
authors.lastname: Seki
authors.forename: Kaori
authors.initials: K
authors.lastname: Kameyama
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hayashi
authors.forename: Mitsuji
authors.initials: M
authors.lastname: Nagahama
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Masudo
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Fukunari
authors.forename: Kumi
authors.initials: K
authors.lastname: Tanaka
authors.forename: Kiminori
authors.initials: K
authors.lastname: Sugino
authors.forename: Koichi
authors.initials: K
authors.lastname: Ito
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takami
mesh_terms: D000328:Adult; D000368:Aged; D018276:Carcinoma, Medullary / Q000378:metabolism / Q000473:pathology*; D002291:Carcinoma, Papillary / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis / Q000473:pathology*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000378:metabolism / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000378:metabolism / Q000473:pathology*