title: Preheating primes pruners. Gentle warming charges up protein-chopping system in human skin cells.
abstract: Volunteers fill sandbags while storm clouds are brewing so the sacks will be ready when floodwaters rush in. Similarly, skin cells prepare for a flood of molten proteins by reinforcing a protein-chopping system, according to new research. This boost might explain how cells and organisms protect themselves from severe stress.
authors.forename: Mary
authors.initials: M
authors.lastname: Beckman
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology; D000368:Aged; D000375:Aging / Q000502:physiology; D002478:Cells, Cultured; D006358:Hot Temperature; D006801:Humans; D010447:Peptide Hydrolases / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D012867:Skin / Q000166:cytology* / Q000201:enzymology; D012879:Skin Physiological Phenomena
chemical_list: D011506:Proteins; D010447:Peptide Hydrolases