Stewart-Treves syndrome as a rare complication of a hereditary lymphedema.
Lymphangiosarcoma (LAS) may occur as a rare complication of primary lymphedema. A case of LAS in hereditary lymphedema of the lower extremity in a 36-year old female is reported. Despite of chemotherapy, local hyperthermia and later amputation of the extremity the patient died of progressive disease due to pulmonary metastasis. In respect to this case, the different therapeutic concepts, as reported in the literature, and their results are presented and discussed.
Dürr
H R
HR
Department of Orthopaedics and Orthopaedic Surgery, Ludwig-Maximilians-University Munich, Germany. hans_roland.duerr@med.uni-muenchen.de
Pellengahr
C
C
Nerlich
A
A
Baur
A
A
Maier
M
M
Jansson
V
V
D000328:Adult; D000671:Amputation, Surgical; D001706:Biopsy; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D005799:Genes, Dominant; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D007866:Leg / Q000473:pathology; D008204:Lymphangiosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008209:Lymphedema / Q000150:complications* / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D009361:Neoplasm Invasiveness / Q000473:pathology; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000032:analysis; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013577:Syndrome
D019408:Platelet Endothelial Cell Adhesion Molecule-1