title: Cu(I)-catalyzed direct addition and asymmetric addition of terminal alkynes to imines.
abstract: A Cu(I)-catalyzed direct addition of alkynes to imines was developed. The process is simple and provides a diverse range of propargylamines in high enantiomeric excess and good yield both in water and in toluene. The absolute configuration of such addition products has been determined by x-ray crystallography.
authors.affiliation: Department of Chemistry, Tulane University, New Orleans, LA 70118, USA.
authors.forename: Chunmei
authors.initials: C
authors.lastname: Wei
authors.forename: Joel T
authors.initials: JT
authors.lastname: Mague
authors.forename: Chao-Jun
authors.initials: CJ
authors.lastname: Li