Determination of bisphenol A in environmental water at ultra-low level by high-performance liquid chromatography with an effective on-line pretreatment device.
We have developed a simple HPLC method for the microanalysis of bisphenol A (BPA), which is often contained in environmental water and is known as an endocrine disrupter. HPLC coupled with electrochemical detection requires a simpler procedure of pretreatment compared to GC-MS. In this study, we analyzed BPA using molecularly imprinted polymer as an on-line pretreatment device. This polymer has molecular recognition sites and provides specific selectivity in extraction process. Due to this effect, the detection limit obtained with this HPLC was 0.36 ng/l. This method applied to environmental water and purified water samples containing 2-70 ng/l of BPA successfully. Furthermore, UV detection was performed in some actual analyses.
Watabe
Yoshiyuki
Y
Department of Polymer Science and Engineering, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan.
Kondo
Takuya
T
Morita
Masatoshi
M
Tanaka
Nobuo
N
Haginaka
Jun
J
Hosoya
Ken
K
D001559:Benzhydryl Compounds; D004785:Environmental Pollutants / Q000032:analysis*; D010636:Phenols / Q000032:analysis*; D012680:Sensitivity and Specificity; D013056:Spectrophotometry, Ultraviolet; D000098826:Bisphenol A Compounds
D001559:Benzhydryl Compounds; D004785:Environmental Pollutants; D010636:Phenols; C006780:bisphenol A; D000098826:Bisphenol A Compounds