title: Isoamylcobalamin-acetone-water (1/0.385/12.650).
abstract: The title compound, [Co(C(5)H(11))(C(62)H(88)N(13)O(14)P)].0.385C(3)H(6)O.12.650H(2)O, contains the isoamyl (3-methylbutyl) anion bonded to the Co(III) ion through a C atom. The compound is thus a structural analog of the two biologically important vitamin B(12) coenzymes adenosylcobalamin and methylcobalamin. The lower axial Co-N bond length [2.277 (2) A] is one of the longest ever reported for a cobalamin and reflects the strong sigma-donor ability of the isoamyl group.
authors.affiliation: Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, PO Wits, Johannesburg 2050, South Africa. chris@hobbes.gh.wits.ac.za
authors.forename: Christopher B
authors.initials: CB
authors.lastname: Perry
authors.forename: Manuel A
authors.initials: MA
authors.lastname: Fernandes
authors.forename: Helder M
authors.initials: HM
authors.lastname: Marques