title: Treatment for a severe reaction to intravenous administration of diatrizoate in an anesthetized horse.
abstract: A mature horse developed acute signs of bronchoconstriction causing hypoxemia and hypercapnia during anesthesia for computerized tomography of the maxillary sinus after i.v. administration of diatrizoate contrast medium. The horse was treated with aerosolized albuterol, atropine, and oxygen insufflation and recovered uneventfully despite severe hypoxemia and low hemoglobin saturation. The horse's condition continued to improve after treatment, and the horse was discharged with no further complications. Caution is advised with the use of contrast media in anesthetized horses.
authors.affiliation: Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA.
authors.forename: Cornelia I
authors.initials: CI
authors.lastname: Gunkel
authors.forename: Alexander
authors.initials: A
authors.lastname: Valverde
authors.forename: Sheilah A
authors.initials: SA
authors.lastname: Robertson
authors.forename: Margret S
authors.initials: MS
authors.lastname: Thompson
authors.forename: Curry G
authors.initials: CG
authors.lastname: Keoughan
authors.forename: Eric A
authors.initials: EA
authors.lastname: Ferrell
mesh_terms: D000336:Aerosols; D000420:Albuterol / Q000627:therapeutic use; D000758:Anesthesia / Q000662:veterinary; D000818:Animals; D016084:Bronchoconstriction / Q000187:drug effects*; D001993:Bronchodilator Agents / Q000627:therapeutic use; D003287:Contrast Media / Q000008:administration & dosage / Q000009:adverse effects*; D003973:Diatrizoate / Q000008:administration & dosage / Q000009:adverse effects*; D006734:Horse Diseases / Q000139:chemically induced*; D006736:Horses; D006935:Hypercapnia / Q000139:chemically induced / Q000662:veterinary; D000860:Hypoxia / Q000139:chemically induced / Q000662:veterinary; D007275:Injections, Intravenous / Q000662:veterinary; D008297:Male; D008443:Maxillary Sinus / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed / Q000662:veterinary
chemical_list: D000336:Aerosols; D001993:Bronchodilator Agents; D003287:Contrast Media; D003973:Diatrizoate; D000420:Albuterol