title: [Paraneoplastic limbic encephalitis and lung cancer].
abstract: Paraneoplastic limbic encephalitis (PLE) is a disorder characterized by severe cognitive dysfunction and seizures. It is usually associated with small cell lung carcinoma. Diagnosis is difficult because clinical markers are often lacking, and symptoms usually precede the diagnosis of cancer. Serological detection of antineuronal antibodies can be useful. We describe a patient with symptoms of limbic encephalitis, negative for paraneoplastic antibodies, in whom lung cancer was detected.
authors.affiliation: Servicio de Medicina Interna, Complejo Hospitalario Ciudad de Jaén, Jaén. ehpehp@supercable.es
authors.forename: M
authors.initials: M
authors.lastname: Gil Ortega
authors.forename: E
authors.initials: E
authors.lastname: Hernández Pardo
authors.forename: I
authors.initials: I
authors.lastname: Gil Ortega
authors.forename: D
authors.initials: D
authors.lastname: Gil Ortega
authors.forename: J
authors.initials: J
authors.lastname: Quesada Córcoles
authors.forename: G
authors.initials: G
authors.lastname: Gutiérrez Lara
authors.forename: J L
authors.initials: JL
authors.lastname: Fernández Reyes
mesh_terms: D001323:Autoantibodies / Q000032:analysis; D018288:Carcinoma, Small Cell / Q000150:complications* / Q000473:pathology / Q000628:therapy; D017809:Fatal Outcome; D006801:Humans; D020363:Limbic Encephalitis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012640:Seizures / Q000175:diagnosis / Q000209:etiology / Q000628:therapy
chemical_list: D001323:Autoantibodies