Acute HIV revisited: new opportunities for treatment and prevention.
Inability to recognize incident infection has traditionally limited both scientific and public health approaches to HIV disease. Recently, some laboratories have begun adding HIV nucleic acid amplification testing to HIV diagnostic testing algorithms so that acute (antibody-negative) HIV infections can be routinely detected within the first 1-3 weeks of exposure. In this review article, we will highlight critical opportunities for HIV treatment and prevention that are presented by these diagnostic strategies.
Pilcher
Christopher D
CD
Department of Medicine, University of North Carolina at Chapel Hill, 27599-7215, USA. cpilcher@med.unc.edu
Eron
Joseph J
JJ
Galvin
Shannon
S
Gay
Cynthia
C
Cohen
Myron S
MS
D000208:Acute Disease; D015658:HIV Infections / Q000503:physiopathology / Q000517:prevention & control* / Q000628:therapy*; D006801:Humans