Generation of 3-pyridyl biaryl systems via palladium-catalyzed Suzuki cross-couplings of aryl halides with 3-pyridylboroxin.
The synthesis of 3-pyridyl biaryl systems can be readily achieved by means of palladium-catalyzed Suzuki cross-coupling reactions between aryl halides and 3-pyridylboroxin. A series of cross-couplings were conducted in order to investigate the scope and limitations of this protocol.
Cioffi
Christopher L
CL
Medicinal Chemistry Department, Albany Molecular Research Inc., P.O. Box 15098, Albany, NY 12212-5098, USA. chris.cioffi@albmolecular.com
Spencer
William T
WT
Richards
Justin J
JJ
Herr
R Jason
RJ