title: [Ultrasonographic features of orofacial clefts at first trimester of pregnancy: report of two cases].
abstract: Fetal cleft lip and palate are now routinely diagnosed by prenatal ultrasound in the late first and second trimester of pregnancy. We report two cases of bilateral orofacial cleft diagnosed at 10 and 12.5 weeks of gestation by ultrasound. Ultrasound can replace invasive embryoscopy for the early diagnosis of facial cleft, based on specific sonographic signs in high risk patients.
authors.affiliation: Service de Gynécologie Obstétrique, Centre Hospitalier Intercommunal de Poissy-Saint-Germain, 10, rue du Champ-Gaillard, 78300 Poissy.
authors.forename: O
authors.initials: O
authors.lastname: Picone
authors.forename: B
authors.initials: B
authors.lastname: de Keersmaecker
authors.forename: Y
authors.initials: Y
authors.lastname: Ville
mesh_terms: D000028:Abortion, Induced; D000328:Adult; D002971:Cleft Lip / Q000000981:diagnostic imaging* / Q000196:embryology; D002972:Cleft Palate / Q000000981:diagnostic imaging* / Q000196:embryology; D005260:Female; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D013577:Syndrome; D016216:Ultrasonography, Prenatal