title: Yeast sphingolipid metabolism: clues and connections.
abstract: This review of sphingolipid metabolism in the budding yeast Saccharomyces cerevisiae contains information on the enzymes and the genes that encode them, as well as connections to other metabolic pathways. Particular attention is given to yeast homologs, domains, and motifs in the sequence, cellular localization of enzymes, and possible protein-protein interactions. Also included are genetic interactions of special interest that provide clues to the cellular biological roles of particular sphingolipid metabolic pathways and specific sphingolipids.
authors.affiliation: Department of Biometry and Epidemiology, Medical University of South Carolina, Charleston, 29425, USA.
authors.forename: Kellie J
authors.initials: KJ
authors.lastname: Sims
authors.forename: Stefka D
authors.initials: SD
authors.lastname: Spassieva
authors.forename: Eberhard O
authors.initials: EO
authors.lastname: Voit
authors.forename: Lina M
authors.initials: LM
authors.lastname: Obeid
mesh_terms: D008954:Models, Biological; D012441:Saccharomyces cerevisiae / Q000378:metabolism*; D013107:Sphingolipids / Q000378:metabolism*
chemical_list: D013107:Sphingolipids