title: An unusual approach to the synthesis of enantiomerically cis linear homoallylic alcohols based on the steric interaction mechanism of camphor scaffold.
abstract: Camphor is used as the chiral auxiliary for the enantioselective synthesis of cis linear homoallylic alcohols. A range of catalysts, aldehydes, and solvents were investigated to obtain the optimum yield, enantioselectivity, and cis olefinic geometry. [structure: see text]
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.
authors.forename: Chi-Lik Ken
authors.initials: CL
authors.lastname: Lee
authors.forename: Cheng-Hsia Angeline
authors.initials: CH
authors.lastname: Lee
authors.forename: Kui-Thong
authors.initials: KT
authors.lastname: Tan
authors.forename: Teck-Peng
authors.initials: TP
authors.lastname: Loh
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis*; D000447:Aldehydes / Q000737:chemistry; D000475:Alkenes / Q000737:chemistry; D000498:Allyl Compounds / Q000138:chemical synthesis*; D002164:Camphor / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D012997:Solvents / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000438:Alcohols; D000447:Aldehydes; D000475:Alkenes; D000498:Allyl Compounds; D012997:Solvents; D002164:Camphor