title: Catalytic regiodivergent kinetic resolution of allylic epoxides: a new entry to allylic and homoallylic alcohols with high optical purity.
abstract: A novel regiodivergent kinetic resolution of a series of allylic epoxides with alkylzinc reagents is described. Results demonstrate the potential of chiral copper-phosphoramidite catalysts for enantiomer differentiation of allylic epoxides, allowing a chiral catalyst-stereoregulated synthesis of cyclic allylic and homoallylic alcohols with high optical purities.
authors.affiliation: Dipartimento di Chimica Bioorganica e Biofarmacia, Università di Pisa, Via Bonanno 33, 56126 Pisa, Italy. pineschi@farm.unipi.it
authors.forename: Mauro
authors.initials: M
authors.lastname: Pineschi
authors.forename: Federica
authors.initials: F
authors.lastname: Del Moro
authors.forename: Paolo
authors.initials: P
authors.lastname: Crotti
authors.forename: Valeria
authors.initials: V
authors.lastname: Di Bussolo
authors.forename: Franco
authors.initials: F
authors.lastname: Macchia