title: [Outpatient chemotherapy and clinical pathway for non-small cell lung cancer].
abstract: We investigated the usefulness of outpatient chemotherapy in 54 cases of non-small cell lung cancer in which outpatient chemotherapy was performed between August 1999 and October 2001. This chemotherapy accounted for 67% of all chemotherapy. Assessment of therapeutic effect revealed a PR in 14 of the 54 cases, and the efficacy rate was 26%. Therapeutic effect according to chemotherapy regimen revealed the highest efficacy rate, 50%, for paclitaxel + CBDCA. The median survival time was 14.7 months, and the 1-year survival rate was 61.1%. On the basis of the above results, a 16-day inpatient clinical pathway using weekly paclitaxel + CBDCA was devised for non-small cell lung cancer. The aim was to shorten the number of inpatient days, standardize treatment, and introduce outpatient chemotherapy. The clinical pathway was introduced in 8 patients with recurrent non-small cell lung cancer between August and October 2002. Variance was found only in one patient whose hospital discharge had to be postponed by two days because of a Grade 3 side effect. Introduction of a clinical pathway with weekly paclitaxel + CBDCA successfully reduced the inpatient days to an average of 16.3 days.
authors.affiliation: Department of Respiratory Medicine, Osaka Police Hospital, 10-31 Kitayama-cho, Tennoji-ku, Osaka City, 543-0035 Osaka, Japan.
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Komuta
authors.forename: Seiichi
authors.initials: S
authors.lastname: Nobuyama
authors.forename: Kouta
authors.initials: K
authors.lastname: Iwahori
authors.forename: Chika
authors.initials: C
authors.lastname: Mukouchi
authors.forename: Keisuke
authors.initials: K
authors.lastname: Koga
authors.forename: Junpei
authors.initials: J
authors.lastname: Kondo
authors.forename: Mitsuko
authors.initials: M
authors.lastname: Asai
authors.forename: Seigo
authors.initials: S
authors.lastname: Minami
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016190:Carboplatin / Q000008:administration & dosage; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy*; D019091:Critical Pathways; D005260:Female; D006801:Humans; D007902:Length of Stay; D008175:Lung Neoplasms / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010045:Outpatients; D017239:Paclitaxel / Q000008:administration & dosage; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D016190:Carboplatin; D017239:Paclitaxel