title: Evaluation of water jet morcellation as an alternative to hand morcellation of renal tissue ablation during laparoscopic nephrectomy: an in vitro study.
abstract: OBJECTIVE
  To evaluate the feasibility and safety of morcellation with a new prototype device that uses high-pressure water flow as a cutting/ablating tool and compare it with standard manual morcellation.
  
  
  METHODS
  Ten porcine kidneys were morcellated with the new water jet device and ten with conventional manual morcellation. Morcellation in all cases was performed in commercially available entrapment bags. The two groups were evaluated for morcellation time, fragment size, and perforation rates (macroscopic and microscopic).
  
  
  RESULTS
  The kidney size in both groups was similar. Morcellation was significantly (P <0.0001) faster in the water jet morcellator group than in the hand morcellation group (5.6 versus 11.9 minutes). The macroscopic evaluation after filling the entrapment bags with normal saline revealed 4 (40%) and 2 (20%) pinhole perforations in the water jet and hand morcellation groups, respectively. The microscopic evaluation revealed an 80% perforation rate in the water jet group and a 20% rate in the hand morcellator group. The size of the resulting fragments in the water jet group was not available, because the morcellated kidney was transformed in a semiliquid form. Therefore, cytology evaluation of the tissue was not possible.
  
  
  CONCLUSIONS
  Water jet technology can be used to morcellate renal porcine tissue effectively. It is faster, but the problems of safety and histologic evaluation must be solved before this promising technology can be used in a clinical setting.
authors.affiliation: James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287-8915, USA.
authors.forename: John M
authors.initials: JM
authors.lastname: Varkarakis
authors.forename: Marc
authors.initials: M
authors.lastname: McAllister
authors.forename: Albert M
authors.initials: AM
authors.lastname: Ong
authors.forename: Stephen B
authors.initials: SB
authors.lastname: Solomon
authors.forename: Mohamad E
authors.initials: ME
authors.lastname: Allaf
authors.forename: Takeshi
authors.initials: T
authors.lastname: Inagaki
authors.forename: Sam B
authors.initials: SB
authors.lastname: Bhayani
authors.forename: Bruce
authors.initials: B
authors.lastname: Trock
authors.forename: Thomas W
authors.initials: TW
authors.lastname: Jarrett
mesh_terms: D000818:Animals; D004210:Dissection / Q000295:instrumentation / Q000379:methods; D005240:Feasibility Studies; D066298:In Vitro Techniques; D007668:Kidney / Q000033:anatomy & histology / Q000166:cytology / Q000601:surgery; D010535:Laparoscopy / Q000379:methods*; D008853:Microscopy; D023421:Models, Animal; D009392:Nephrectomy / Q000295:instrumentation* / Q000379:methods; D011312:Pressure; D013525:Surgical Instruments / Q000592:standards*; D013552:Swine; D014867:Water
chemical_list: D014867:Water