title: [Evaluation of salivary gland function in women with autoimmune thyroid diseases].
abstract: The function of the salivary glands is regulated by nervous system which influences salivary circulation. Moreover the volume of secreted saliva depends on the humoral agents, including thyroid hormones. The aim of the study was to determine the quantity of the secreted mixed resting and stimulated saliva in women with autoimmune thyroid diseases (AITD) depending on the function of the thyroid gland (hyperthyroidism, hypothyroidism and euthyroidism). The association between thyroid antibody concentrations (TPO-Ab, Tg-Ab, TR-Ab) and volume of secreted saliva was also examined. Studies were performed in 106 women suffering from AITD and 15 healthy volunteers. In hyperthyroid women there was a decrease in volumes of resting (57.14%) and stimulated (89.29%) saliva. Similarly, a decrease in secretion of resting (75%) and stimulated (66.67%) saliva was shown in hypothyroid women. In euthyroid patients with AITD there was a partial normalisation of salivary glands function. The negative correlation between concentrations of TPO-Ab, Tg-Ab and the volume of resting and stimulated saliva was found. In conclusion, AITD may be associated with disturbances in salivary secretion which depends on thyroid hormones production. It can be suggested that autoimmunological processes within salivary glands may influence their function.
authors.affiliation: Katedry i Zakładu Stomatologii Zachowawczej i Chorób Przyzebia, Slaskiej Akademii Medycznej w Katowicach.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Koczor-Rozmus
authors.forename: Krystyna
authors.initials: K
authors.lastname: Zwirska-Korczala
authors.forename: Jadwiga
authors.initials: J
authors.lastname: Sadlak-Nowicka
authors.forename: Leşzek
authors.initials: L
authors.lastname: Ilewicz
authors.forename: Danuta
authors.initials: D
authors.lastname: Mayer-Parka
authors.forename: Beata
authors.initials: B
authors.lastname: Wierucka-Młynarczyk
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008875:Middle Aged; D012463:Saliva / Q000378:metabolism*; D012469:Salivary Glands / Q000503:physiopathology*; D013961:Thyroid Gland / Q000276:immunology*; D013967:Thyroiditis, Autoimmune / Q000097:blood / Q000150:complications* / Q000503:physiopathology*