[Inappropriate secretion of antidiuretic hormone and diabetes insipidus after surgery for pituitary adenoma].
The purpose of our study was to evaluate the incidence and risk factors of SIADH (syndrome of inappropriate antidiuretic hormone) and diabetes insipidus after pituitary adenoma surgery in patients and report follow-up data collected in our department of endocrinology. This retrospective study included 78 patients seen in the last 5 years. Possible risk factors of SIADH and diabetes insipidus were studies: patient age and gender, type of secretion, tumor volume, surgical approach, presence of postoperative pituitary failure. The incidence of SIADH and diabetes insipidus were similar: 12.8%. We did not find any risk factor for SIADH associated with postoperative anterior pituitary failure. This study illustrates the importance of postoperative follow-up after pituitary adenoma surgery.
Ionescu
O
O
Service d'Endocrinologie, Hôpital de la Cavale Blanche, 29200 Brest, France.
Sonnet
E
E
Roudaut
N
N
Bercovici
J P
JP
Kerlan
V
V
D000236:Adenoma / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003919:Diabetes Insipidus / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000601:surgery*; D011183:Postoperative Complications; D012189:Retrospective Studies; D012307:Risk Factors