Effectiveness of tirofiban for failed thrombolysis during acute myocardial infarction.
The clinical outcome of 48 consective patients with myocardial infarction who received tirofiban for unsuccessful thrombolysis was compared with that of 48 patients matched for age, gender, and infarct location who did not receive rescue treatment. Those who received tirofiban had more successful reperfusions, and there were few bleeding complications.
Vetrano
Alfredo
A
Department of Cardiology, ICCU, Azienda Ospedaliera San Sebastiano, Caserta, Italy. alfredovetrano@virgilio.it
Carotenuto
Raffaele
R
Corsini
Fabrizio
F
Schioppa
Margherita
M
Martone
Angela
A
Melorio
Saverio
S
Sideri
Francesca
F
Romano
Salvatore
S
Chieffo
Carmelo
C
Corsini
Giancarlo
G
D000368:Aged; D005240:Feasibility Studies; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors*; D019233:Retreatment / Q000379:methods; D015912:Thrombolytic Therapy; D000077466:Tirofiban; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D017211:Treatment Failure; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000627:therapeutic use*
D005343:Fibrinolytic Agents; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D014443:Tyrosine; D010959:Tissue Plasminogen Activator; D000077466:Tirofiban