title: Key roles of enzyme positions and membrane surface potentials in the properties of biomimetic membranes.
abstract: The coupling of diffusion, reaction, and electrostatic interactions existing in the microenvironment of permeable and charged bi-enzymatic membranes has led to the concept of biomimetic membranes. These membranes permit the active and specific transport of small hydrophilic molecules against their concentration gradients, at constant temperature and pressure. This study shows that such membranes behave in totally different ways, depending both on the relative position of the two enzymes, either within or outside the ionic double layer, and on the membrane surface potentials.
authors.affiliation: Laboratoire d'Automatique et de Génie des Procédés, UMR-CNRS 5007, CPE Lyon, France.
authors.forename: C
authors.initials: C
authors.lastname: Charcosset
authors.forename: K
authors.initials: K
authors.lastname: Fiaty
authors.forename: B
authors.initials: B
authors.lastname: Perrin
authors.forename: R
authors.initials: R
authors.lastname: Couturier
authors.forename: B
authors.initials: B
authors.lastname: Maïsterrena
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry*; D032701:Biomimetics / Q000379:methods; D003198:Computer Simulation; D004563:Electrochemistry / Q000379:methods*; D004798:Enzymes / Q000737:chemistry*; D007473:Ion Channels / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry*; D046911:Macromolecular Substances; D008422:Materials Testing; D008560:Membrane Fluidity; D008564:Membrane Potentials; D008567:Membranes, Artificial; D008954:Models, Biological; D008956:Models, Chemical; D008968:Molecular Conformation
chemical_list: D004798:Enzymes; D007473:Ion Channels; D008051:Lipid Bilayers; D046911:Macromolecular Substances; D008567:Membranes, Artificial