title: Magnetic resonance angiography versus duplex arteriography in patients undergoing lower extremity revascularization: which is the best replacement for contrast arteriography?
abstract: OBJECTIVE
  In an effort to explore alternatives to contrast material-enhanced arteriography, we compared magnetic resonance angiography (MRA) and duplex arteriography (DA) with contrast arteriography (CA) for defining anatomic features in patients undergoing lower extremity revascularization.
  
  
  METHODS
  From August 1, 2001, to August 1, 2002, 61 consecutive inpatients (64 limbs) with chronic lower extremity ischemia underwent CA, MRA, and DA before undergoing lower extremity revascularization procedures. The reports of these tests and images were compared prospectively, and the differences in the iliac, femoropopliteal, and infrapopliteal segments were noted. The vessels were classified as mildly diseased (<50%), moderately diseased (50%-70%), severely diseased (71%-99%), or occluded. The studies and treatment plans based on these data were compared.
  
  
  RESULTS
  Mean patient age was 76 +/- 10 years (SD). Indications for the procedures included gangrene (43%), ischemic ulcer (28%), rest pain (19%), severe claudication (9%), and failing bypass (1%). During this period 35 patients were ineligible for the protocol, because they could not undergo MRA (n=27) or angiography (n=8). Of the total 192 segments in the 64 patients (iliac, femoropopliteal, tibial), 17% were not able to be fully assessed with DA, and 7% with MRA. Disagreements with CA and DA were found in the iliac, femoropopliteal, and tibial segments in 0%, 7%, and 14% of cases, respectively, and between CA and MRA in 10%, 26%, and 42% of cases, respectively. Two of 9 differences (22%) between DA and CA were thought to be clinically significant, and 28 of 45 differences (62%) between MRA and CA were thought to be clinically significant.
  
  
  CONCLUSIONS
  A review of the data obtained in this series indicates that MRA does not yet seem to yield adequate data, at least in this highly selected population at our institution. When severe calcification is identified, CA may be necessary in patients undergoing DA.
authors.affiliation: Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA.
authors.forename: Anil
authors.initials: A
authors.lastname: Hingorani
authors.forename: Enrico
authors.initials: E
authors.lastname: Ascher
authors.forename: Natalia
authors.initials: N
authors.lastname: Markevich
authors.forename: Sreedhar
authors.initials: S
authors.lastname: Kallakuri
authors.forename: Alex
authors.initials: A
authors.lastname: Hou
authors.forename: Richard
authors.initials: R
authors.lastname: Schutzer
authors.forename: William
authors.initials: W
authors.lastname: Yorkovich
mesh_terms: D000368:Aged; D000792:Angiography / Q000379:methods*; D003287:Contrast Media; D006801:Humans; D007511:Ischemia / Q000175:diagnosis* / Q000601:surgery; D035002:Lower Extremity / Q000098:blood supply* / Q000601:surgery; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008875:Middle Aged; D011446:Prospective Studies; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex / Q000379:methods*; D014656:Vascular Surgical Procedures / Q000379:methods*
chemical_list: D003287:Contrast Media