[The cause of re-stenosis in the stent].
One of the probable causes of restenosis occurrence in the stent was analyzed. Experience of surgical treatment of 59 patients with an acute vascular trauma, of the complex cutaneous flaps transplantation and of interventions on lymphovenous system was summarized. There were also conducted experimental investigations in 64 rats and in 54 rabbits, histological preparations of the vessels wall were studied. There was proved that restenosis in the stent may occur due to atrophy of muscular layer of artery, migration and subsequent proliferation of the smooth muscle cells in neointyma after sclerosis of adventitia. It is necessary to use for the stents manufacturing an expansible-dynamical constructions, which promote an active functioning of muscular layer of arterial wall without causing its atrophy.
Lazarenko
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D000293:Adolescent; D000328:Adult; D000818:Animals; D001284:Atrophy / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006083:Graft Occlusion, Vascular; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011817:Rabbits; D051381:Rats; D015607:Stents