[Induction of osteointegration of rabbit mandibular central fissure with guided tissue regeneration]
OBJECTIVE:To observe the effect of guided tissue regeneration (GTR) on induction of ostegenesis in developmental bone clefts,and provide a basis for the use of GTR to repair bony clefts in cleft lip and palate patients.METHODS:The e-PTFE membrane was placed on the labial and lingual sides of the rabbit mandibular central fissure.A radiological and pathological study was performed to determine the healing of the fissure integration.RESULTS:The results showed that the bony cleft was completely integrated 4 weeks after placement of the barrier membrane.CONCLUSION:GTR is an effective approach to reconstruct bony cleft,and is likely to be used in repair of alveolar cleft and cleft palate.
Xu
X
X
Affiliated Hospital of Stomatology,Shandong Medical University.Jinan 250012, Shandong province, China.
Yang
P S
PS
Ma
Y
Y
Sun
S Z
SZ
Li
Q
Q
Wang
J T
JT