[Effect of complex dribbing-pill of xue shuan tong on thrombus formation and microcirculation in rat].
OBJECTIVE
To investigate the effect of Chinese traditional medicine complex dribbing-pill of Xue Shuan Tong on thrombus formation in vivo and thrombolysis in vitro of rats.


METHODS
Thrombus and thrombolysis were evaluated by carotid artery-jugular vein circuit in vivo and constant temperature natural lysis in vitro respectively.


RESULTS
Complex dribbing-pill of Xue Shuan Tong could significantly inhibit thrombus formation in vivo. Coagulated blood could be apparently dissolved by complex dribbing-pill of Xue Shuan Tong.


CONCLUSIONS
Complex dribbing-pill of Xue Shuan Tong could significantly inhibit the thrombus and increase thrombolysis.
Zhang
Jianhao
J
Sun Yet-sen Ophthalmic Center of Sun Yet-sen University, Guangzhou 510060.
Huang
Qiaobing
Q
Liu
Yuhua
Y
Huang
Xuliang
X
Zhao
Guiling
G
Pan
Bingxing
B
Kan
Wenhong
W
Zhao
Kesen
K
D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D002341:Carotid Artery Thrombosis / Q000209:etiology; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D066298:In Vitro Techniques; D008297:Male; D010946:Plants, Medicinal; D010974:Platelet Aggregation / Q000187:drug effects; D051381:Rats; D017207:Rats, Sprague-Dawley; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000188:drug therapy*
D004365:Drugs, Chinese Herbal; D005343:Fibrinolytic Agents