Invitro drug sensitivity of Trichophyton species against griseofulvin and ketoconazole.
The in vitro activity of griseofulvin and ketoconazole was investigated against Trichophyton mentagrophytes (Robin) Blanchard and T. Simii (Pinoy) Stockdale, Mackenzie and Austwick. A gradual decrease in growth was observed with increase in concentration of both antibiotics. Ketoconazole was the more effective antibiotic than griseofulvin as it observed to inhibit > 50% mycelial weight even at a lower concentration of 100 ppm. While griseofulvin was effective to cause > 50% growth inhibition only at higher dosage of 400 ppm.
Dodia
Sumita
S
Department of Botany, St. John's College, Agra 282 002, India.
Bajpai
Ritu
R
Singh
B Geetha
BG
D000935:Antifungal Agents / Q000494:pharmacology*; D003881:Dermatomycoses / Q000382:microbiology; D006118:Griseofulvin / Q000494:pharmacology*; D006801:Humans; D007654:Ketoconazole / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D014249:Trichophyton / Q000187:drug effects*
D000935:Antifungal Agents; D006118:Griseofulvin; D007654:Ketoconazole