[Exploration of the pathogenesis and the management of hypernatremia in burn patients].
OBJECTIVE
To explore the pathogenesis and the management of hypernatremia in burn patients.


METHODS
Twenty eight burn patients with hypernatremia were enrolled in the study and were divided into infection and non-infection groups. The pathogenesis, clinical features, biochemical indices in blood, the therapeutic results and the prognosis were compared between the two groups.


RESULTS
In non-infection group, the hypernatremia was mainly induced by improper fluid resuscitation and occurred on the 3.1 postburn day (PBD), while that in the infected group, on 7.2 PBD. The patients in non-infected group exhibited much more excited and the blood levels of glucose and urea nitrogen (BUN) were obviously decreased when compared with those in the infected group (P < 0.01). The survival rate in non-infected and infected group were 94.12% and 9.09%, respectively.


CONCLUSIONS
The mortality rate of the patients with hypernatremia could be lowered by means of taking optimal measures according to the different patterns of hypernatremia.
Yuan
Shi-an
SA
Department of Burns The 159th Hospital of People's Liberation Army. Zhumadian 463000, P.R. China.
Yang
Xiao-dong
XD
Zhang
Hong
H
Yang
Cai-yun
CY
Xiao
Rong
R
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D001806:Blood Urea Nitrogen; D002056:Burns / Q000097:blood / Q000150:complications* / Q000401:mortality; D005260:Female; D006801:Humans; D006955:Hypernatremia / Q000209:etiology* / Q000401:mortality / Q000628:therapy; D007239:Infections / Q000150:complications*; D008297:Male; D008875:Middle Aged; D015996:Survival Rate; D016896:Treatment Outcome
D001786:Blood Glucose