[Clinical observation on effect of xuesaitong injection as auxiliary treatment of severe craniocerebral injury].
OBJECTIVE
To evaluate the effect of Xuesaitong injection (XSTI, a preparation of Panax Notoginseng) as auxilliary treatment of severe craniocerebral injury.


METHODS
Eighty-seven patients with severe craniocerebral injury were selected and randomly divided into the treated group (n = 44) and the control group (n = 43), they were treated with conventional treatment, and XSTI was given additionally to the treated group. Intracranial pressure (ICP) and Glasgow coma score (GCS) of all patients were measured after 1 or 2-week treatment, and Glasgow outcome scale (GOS) of them was determined 3 months later. Then the therapeutic effect in the two groups were compared.


RESULTS
After treatment, the ICP was lower, GCS higher and GOS better in the treated group than those in the control group significantly, all showing statistical significance (P < 0.05).


CONCLUSIONS
XSTI has marked clinical therapeutic effect in treating patients with severe craniocerebral injury.
Ai
Wen-bing
WB
Department of Neurosurgery, Affiliated Renhe Hospital of Three Gorges University, Hubei 443001. aiwbing@hotmail.com
Chen
Yu-hong
YH
Yang
Qi-jian
QJ
D000328:Adult; D001930:Brain Injuries / Q000188:drug therapy / Q000601:surgery; D006259:Craniocerebral Trauma / Q000188:drug therapy* / Q000601:surgery; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005260:Female; D015600:Glasgow Coma Scale; D023261:Glasgow Outcome Scale; D006801:Humans; D008297:Male; D018696:Neuroprotective Agents / Q000627:therapeutic use; D005894:Panax / Q000737:chemistry; D008517:Phytotherapy; D012503:Saponins / Q000008:administration & dosage
D004365:Drugs, Chinese Herbal; D018696:Neuroprotective Agents; D012503:Saponins