title: Sleep disturbances among methadone maintained patients.
abstract: We examined the relationship of sleep disturbance and demographic, mental health, drug use and other factors among 225 methadone-maintained individuals. The cohort was 78% Caucasian and 54% male with a mean age of 41 years. Sleep disturbance was measured using the Pittsburgh Sleep Quality Index (PSQI) with a score >5 indicating poor global sleep quality. Eighty-four percent of subjects had PSQI scores of six or higher. In multivariate analysis, depressive symptoms, anxiety symptoms, greater nicotine dependence, bodily pain, and unemployment were associated with poorer global sleep quality (p <.01). Targeting modifiable psychological and medical risk factors that are most strongly associated with sleep disturbance may improve quality of life in drug treatment.
authors.affiliation: Rhode Island Hospital, Division of General Internal Medicine, 593 Eddy Street, Providence, RI, USA. mstein@lifespan.org
authors.forename: Michael D
authors.initials: MD
authors.lastname: Stein
authors.forename: Debra S
authors.initials: DS
authors.lastname: Herman
authors.forename: Shaughna
authors.initials: S
authors.lastname: Bishop
authors.forename: Joanna A
authors.initials: JA
authors.lastname: Lassor
authors.forename: Marjorie
authors.initials: M
authors.lastname: Weinstock
authors.forename: Jennifer
authors.initials: J
authors.lastname: Anthony
authors.forename: Bradley J
authors.initials: BJ
authors.lastname: Anderson
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000009:adverse effects / Q000453:epidemiology; D005260:Female; D006801:Humans; D016018:Least-Squares Analysis; D008297:Male; D008691:Methadone / Q000009:adverse effects / Q000627:therapeutic use*; D009293:Opioid-Related Disorders / Q000150:complications* / Q000188:drug therapy*; D010146:Pain / Q000150:complications / Q000453:epidemiology; D015995:Prevalence; D012893:Sleep Wake Disorders / Q000453:epidemiology* / Q000209:etiology; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D014481:United States / Q000453:epidemiology
chemical_list: D008691:Methadone