title: [Fibromyalgia].
abstract: Within clinical practice fibromyalgia is diagnosed according to the classification criteria of the American College of Rheumatology. The examination of the tender points is still to be standardized. By using additional diagnostic criteria fibromyalgia changes into a polysymptomatic syndrom with multiple functional and psychic symptoms. The prevalence of FMS is estimated to range between 1,3-4,8% in the general population. Relative hypocortisolism, sensory hypervigilance, adverse life experiences and psychiatric disorders are discussed as main pathophysiological mechanisms. There are no evidence-based guidelines of scientific societies for the management of fibromyalgia available. Patient education, medical training therapy, physical therapy (heat or cold) and relaxation therapy are recommended. There is a moderate evidence for the effectiveness of tricyclic antidepressants and aerobic training. The effectiveness of multicomponent therapy in fibromyalgia is still to be demonstrated.
authors.affiliation: Internistisch-rheumatologische Schwerpunktpraxis, Saarbrücken. Drwerner@biewer.com
authors.forename: W
authors.initials: W
authors.lastname: Biewer
authors.forename: I
authors.initials: I
authors.lastname: Conrad
authors.forename: W
authors.initials: W
authors.lastname: Häuser
mesh_terms: D003937:Diagnosis, Differential; D005356:Fibromyalgia / Q000145:classification / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D012959:Socioeconomic Factors