title: [Efficacy of the medical treatment of adenoid hypertrophy in children with house dust mite allergy].
abstract: Allergic sensitisation of the airways occurs in the mucosa of the shock organ, or in the lymphatic stations draining these structures. The lymphatic structure closest to the nasal mucosa in humans is the adenoid. Pediatric adenoidal obstruction of the nasal airway is associated with significant morbidity and is a frequent indication for surgery. Because efficacious medical alternatives to adenoidectomy are lacking, we assessed the potency of standard-dose topical nasal fluticasone propionate and Cetirizine in reduction of adenoidal obstruction of the nasal airway. To examine the influence of these medicines on the adenoid hypertrophy (AH) we studied 43 children ages 4 to 9 years, who had AH and house dust mite allergy. Properly administered aqueous nasal fluticasone propionate and Cetirizine in standard doses can significantly reduce adenoidal hypertrophy and nasal airway obstructive symptoms in atopic children.
authors.affiliation: Poradnia Alergologiczna NZOZ Euromedica 86-300 Grudziadz, ul. Chełmska 74.
authors.forename: Marek
authors.initials: M
authors.lastname: Modrzyński
authors.forename: Edward
authors.initials: E
authors.lastname: Zawisza
authors.forename: Piotr
authors.initials: P
authors.lastname: Rapiejko
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Przybylski
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Lipiec
authors.forename: Janusz
authors.initials: J
authors.lastname: Królikiewicz
mesh_terms: D000234:Adenoids / Q000187:drug effects* / Q000473:pathology / Q000601:surgery*; D000281:Administration, Intranasal; D000287:Administration, Topical; D000730:Androstadienes / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use*; D018926:Anti-Allergic Agents / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use*; D017332:Cetirizine / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D000068298:Fluticasone; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy* / Q000276:immunology*; D006984:Hypertrophy / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D008297:Male; D039981:Pyroglyphidae
chemical_list: D000730:Androstadienes; D018926:Anti-Allergic Agents; D000893:Anti-Inflammatory Agents; D000068298:Fluticasone; D017332:Cetirizine