Quinone reductase-mediated nitro-reduction: clinical applications.
Knox
Richard J
RJ
Enact Pharma PLC, Salisbury, United Kingdom.
Chen
Shiuan
S
D000595:Amino Acid Sequence; D000818:Animals; D000970:Antineoplastic Agents / Q000493:pharmacokinetics; D001388:Aziridines / Q000737:chemistry / Q000493:pharmacokinetics; D001711:Biotransformation; D002986:Clinical Trials as Topic; D006801:Humans; D008969:Molecular Sequence Data; D009601:Nitroreductases / Q000378:metabolism*; D011355:Prodrugs / Q000737:chemistry / Q000493:pharmacokinetics; D011808:Quinone Reductases / Q000502:physiology*
D000970:Antineoplastic Agents; D001388:Aziridines; D011355:Prodrugs; C100099:tretazicar; D011808:Quinone Reductases; D009601:Nitroreductases