An algebraic model of RNA duplex formation.
We propose a simple algebraic description of the two-body interactions of bases in RNA thermodynamics showing in detail qualitative equivalence with conventional nearest-neighbor models. The process of obtaining base content, polymer, and oligomer parameters is illustrated, and for duplexes containing Watson-Crick pairs, fits to oligonucleotide duplex heat-of-formation data are shown to be statistically equivalent to existing models.
Bashford
J D
JD
School of Mathematics and Physics, University of Tasmania, P. O. Box 252-37, Hobart 7001, Tasmania, Australia. jdb@postoffice.utas.edu.au
Jarvis
P D
PD
D020029:Base Pairing; D006860:Hydrogen Bonding; D008956:Models, Chemical; D009690:Nucleic Acid Conformation; D009692:Nucleic Acid Heteroduplexes / Q000737:chemistry*; D012313:RNA / Q000737:chemistry*; D013816:Thermodynamics
D009692:Nucleic Acid Heteroduplexes; D012313:RNA