title: [Observation on clinical effect of Angelica injection in treating acute cerebral infarction].
abstract: OBJECTIVE
  To study the therapeutic effect of Angelica Injection (AI) in treating acute cerebral infarction (ACI).
  
  
  METHODS
  One thousand four hundred and four patients, who were treated with AI (692 patients in Group A), compound salvia (390 patients in Group B) and low molecular dextran injection (322 patients in Group C) respectively. Indexes such as CT scanning on infarcted volume, scoring of clinical neuro-function deficit taking on the 1st, 3rd, 7th, 15th and 25th day, clinical therapeutic effectiveness evaluated by the end of the 2nd week and the improvement of Barthel index scores were observed.
  
  
  RESULTS
  The total effective rate in Group A, B and C was 78.7%, 63.6% and 59.3% respectively, that in Group A was significantly higher than in the other two groups (P < 0.05). The improvement of neuro-function deficit scores and Barthel scores in Group A were better than those in Group B and C (on the 25th day, P < 0.01), and the decrement of infarcted volume in Group A was larger than that in Group C (P < 0.01).
  
  
  CONCLUSIONS
  AI has evident therapeutic effect in treating ACI.
authors.affiliation: Department of Neurology, Zhongnan Hospital, Wuhan University, Wuhan 430071.
authors.forename: Yu-min
authors.initials: YM
authors.lastname: Liu
authors.forename: Jun-jian
authors.initials: JJ
authors.lastname: Zhang
authors.forename: Jian
authors.initials: J
authors.lastname: Jiang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D029971:Angelica sinensis / Q000737:chemistry; D002544:Cerebral Infarction / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy
chemical_list: D004365:Drugs, Chinese Herbal