Photolithographic synthesis of peptoids.
We describe a novel photolithographic approach to the synthesis of peptoids (oligo-N-substituted glycines). This strategy enables the construction of a spatially addressable peptoid microarray, thus providing a potentially powerful tool for the discovery of protein ligands.
Li
Shuwei
S
Center for Biomedical Inventions and the Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Bowerman
Dawn
D
Marthandan
Nishanth
N
Klyza
Stanley
S
Luebke
Kevin J
KJ
Garner
Harold R
HR
Kodadek
Thomas
T