title: 2-O-(beta-D-Glucopyranosyl)ascorbic acid, a novel ascorbic acid analogue isolated from Lycium fruit.
abstract: A novel stable precursor of ascorbic acid (vitamin C), 2-O-(beta-D-glucopyranosyl)ascorbic acid, was isolated from both the ripe fresh fruit and dried fruit of Lycium barbarum L., a plant of the Solanaceae family. The chemical structure was inferred by instrumental analyses and confirmed by chemical synthesis. The dried fruit of Lycium barbarum L. contained ca. 0.5% of it, which is comparable to the ascorbic acid content of fresh lemons. It increased the blood ascorbic acid by oral administration to rats, and it was also detected in blood from the portal vein.
authors.affiliation: Health Care Science Laboratory, Institute for Food & Beverage, Technological Development Center, Suntory Ltd., 5-2-5, Yamazaki, Shimamoto-cho, Mishima-gun, Osaka 618-0001, Japan.
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Toyoda-Ono
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Maeda
authors.forename: Masahiro
authors.initials: M
authors.lastname: Nakao
authors.forename: Makiko
authors.initials: M
authors.lastname: Yoshimura
authors.forename: Namino
authors.initials: N
authors.lastname: Sugiura-Tomimori
authors.forename: Harukazu
authors.initials: H
authors.lastname: Fukami
mesh_terms: D000818:Animals; D001205:Ascorbic Acid / Q000031:analogs & derivatives / Q000097:blood / Q000302:isolation & purification* / Q000493:pharmacokinetics; D002851:Chromatography, High Pressure Liquid; D005638:Fruit / Q000737:chemistry*; D007408:Intestinal Absorption; D032305:Lycium / Q000737:chemistry*; D015394:Molecular Structure; D051381:Rats
chemical_list: C484753:2-O-(beta-D-glucopyranosyl)ascorbic acid; D001205:Ascorbic Acid