title: [Thalidomide--a new prospective therapy in rheumatology and transplantation].
abstract: This review article discusses the thalidomide therapy of diseases such as systemic sclerosis, rheumatoid arthritis, Behçet syndrome, lupus erythematosus disseminatus and graft-versus-host disease. The main mechanism of action of thalidomide in these diseases is probably based on the suppression of tumor necrosis factor-alpha and the modulation of interleukins.
authors.affiliation: Katedry i Kliniki Alergologii i Chorób Wewnetrznych, Akademii Medycznej im. L Rydygiera w Bydgoszczy.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Pałgan
authors.forename: Izabela
authors.initials: I
authors.lastname: Pałgan
authors.forename: Andrzej
authors.initials: A
authors.lastname: Dziedziczko
mesh_terms: D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D001528:Behcet Syndrome / Q000188:drug therapy*; D006086:Graft vs Host Disease / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007378:Interleukins / Q000378:metabolism; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy*; D012595:Scleroderma, Systemic / Q000188:drug therapy*; D013792:Thalidomide / Q000494:pharmacology*; D014409:Tumor Necrosis Factor-alpha / Q000187:drug effects
chemical_list: D007166:Immunosuppressive Agents; D007378:Interleukins; D014409:Tumor Necrosis Factor-alpha; D013792:Thalidomide