title: Endocarditis with ruptured cerebral aneurysm caused by Cardiobacterium valvarum sp. nov.
abstract: A fastidious gram-negative bacterium was isolated from the blood of a 37-year-old man who had insidious endocarditis with a sudden rupture of a cerebral aneurysm. Characterization of the organism through phylogenetic and phenotypic analyses revealed a novel species of Cardiobacterium, for which the name Cardiobacterium valvarum sp. nov. is proposed. C. valvarum will supplement the current sole species Cardiobacterium hominis, a known cause of endocarditis. Surgeries and antibiotic treatment cured the patient's infection and associated complications. During cardiac surgery, a congenital bicuspid aortic valve was found to be the predisposing factor for his endocarditis.
authors.affiliation: Section of Clinical Microbiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA . xhan@mdanderson.org
authors.forename: Xiang Y
authors.initials: XY
authors.lastname: Han
authors.forename: Michelle C
authors.initials: MC
authors.lastname: Meltzer
authors.forename: Joan T
authors.initials: JT
authors.lastname: Woods
authors.forename: Victor
authors.initials: V
authors.lastname: Fainstein
mesh_terms: D000328:Adult; D000785:Aneurysm, Infected / Q000150:complications* / Q000382:microbiology; D044066:Cardiobacterium / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D004697:Endocarditis, Bacterial / Q000150:complications / Q000382:microbiology*; D016905:Gram-Negative Bacterial Infections / Q000150:complications / Q000382:microbiology*; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications*; D008297:Male; D012422:Rupture, Spontaneous / Q000150:complications