Clinical, biochemical and ultrasonographic characteristics of Scandinavian women with PCOS.
BACKGROUND
The aim was to investigate the clinical, biochemical and ultrasonographic characteristics of Scandinavian women with polycystic ovarian syndrome (PCOS), and to see whether there were any differences between eumenorrhoic and oligoamenorrhoic women.


METHODS
Eighty women aged between 18 and 40 years with PCOS were investigated in a prospective study. The inclusion criteria were polycystic ovaries (PCO), body mass index (BMI) >25 kg/m(2) and at least one of the following: testosterone >2.5 nmol/L, sex hormone binding globulin (SHBG) <30 nmol/L, fasting C-peptide >1.0 nmol/L, oligoamenorrhea or hirsutism.


RESULTS
Eumenorrhoic and oligoamenorrhoic women with PCOS did not differ in age, age at menarche, blood pressure, BMI, free testosterone index (FTI), insulin C-peptide or fasting glucose. A thicker endometrium and a smaller ovarian volume were found in eumenorrhoic compared to oligoamenorrhoic patients. There was linear association between BMI and the number of diagnostic criteria met.


CONCLUSIONS
BMI was associated with the severity of the PCOS. There were no differences in basic clinical and biochemical parameters between eumenorrhoic and oligoamenorrhoic patients with PCOS.
Vanky
Eszter
E
Department of Obstetrics and Gynecology, University Hospital of Trondheim, Gudruns gate 9, N-7006 Trondheim, Norway. eszter.vanky@medisin.ntnu.no
Kjøtrød
Sigrun
S
Salvesen
Kjell Asmund
KA
Romundstad
Pål
P
Moen
Mette Haase
MH
Carlsen
Sven Magnus
SM
D000328:Adult; D015992:Body Mass Index; D002096:C-Peptide / Q000097:blood; D004717:Endometrium / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008499:Medical Records; D008598:Menstruation; D009664:Norway / Q000453:epidemiology; D010053:Ovary / Q000000981:diagnostic imaging; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000209:etiology; D012189:Retrospective Studies; D012307:Risk Factors; D012738:Sex Hormone-Binding Globulin / Q000378:metabolism; D013739:Testosterone / Q000097:blood; D014463:Ultrasonography
D002096:C-Peptide; D012738:Sex Hormone-Binding Globulin; D013739:Testosterone