title: The immune response to bovine viral diarrhea virus: a constantly changing picture.
abstract: Bovine viral diarrhea virus (BVDV) is one of the major immuno-suppressive viruses of cattle. The effect on the innate and acquired immune system is unique and results in dramatic immune dysfunction. BVDV infection also has the ability to cause persistent infection (PI) in the developing fetus. This Pl syndrome creates a requirement for high levels of BVDV immunity from vaccines to prevent these infections. BVDV vaccines and their future development continue to be an enigma in the control of BVDV.
authors.affiliation: Department of Veterinary Science, South Dakota State University, P.O. Box 2175, Brookings, SD 57007, USA. christopher_chase@sdstate.edu
authors.forename: Christopher C L
authors.initials: CC
authors.lastname: Chase
authors.forename: Gamal
authors.initials: G
authors.lastname: Elmowalid
authors.forename: Ausama A A
authors.initials: AA
authors.lastname: Yousif
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis / Q000276:immunology; D000956:Antigens, Viral / Q000276:immunology; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000276:immunology* / Q000517:prevention & control / Q000821:virology*; D002417:Cattle; D001908:Diarrhea Viruses, Bovine Viral / Q000276:immunology*; D007111:Immunity, Cellular; D007113:Immunity, Innate; D007112:Immunity, Maternally-Acquired; D008264:Macrophages / Q000821:virology; D014765:Viral Vaccines / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral; D014765:Viral Vaccines