title: The effect of mannose binding lectin gene polymorphisms on susceptibility to tuberculosis in different ethnic groups.
abstract: In order to investigate the role of MBL gene polymorphisms in susceptibility to tuberculosis (TB) we genotyped 487 TB cases and 232 controls. Among African-American individuals, the frequency of B allele was lower among controls than cases (p < 0.01), but we found no differences between cases and controls of white and Hispanic ethnicity.
authors.affiliation: Department of Pathology, Baylor College of Medicine, Houston, Texas 77030, USA.
authors.forename: Hana M
authors.initials: HM
authors.lastname: El Sahly
authors.forename: Robert A
authors.initials: RA
authors.lastname: Reich
authors.forename: Shu Jun
authors.initials: SJ
authors.lastname: Dou
authors.forename: James M
authors.initials: JM
authors.lastname: Musser
authors.forename: Edward A
authors.initials: EA
authors.lastname: Graviss
mesh_terms: D000328:Adult; D001741:Black or African American / Q000235:genetics; D000368:Aged; D016022:Case-Control Studies; D004269:DNA, Bacterial / Q000032:analysis; D004198:Disease Susceptibility; D005260:Female; D020022:Genetic Predisposition to Disease; D006630:Hispanic or Latino / Q000235:genetics; D006801:Humans; D015994:Incidence; D008297:Male; D037601:Mannose-Binding Lectin / Q000235:genetics*; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011336:Probability; D012016:Reference Values; D018570:Risk Assessment; D012494:Sampling Studies; D012680:Sensitivity and Specificity; D014397:Tuberculosis, Pulmonary / Q000208:ethnology* / Q000235:genetics*; D014481:United States / Q000453:epidemiology; D044465:White People / Q000235:genetics
chemical_list: D004269:DNA, Bacterial; D037601:Mannose-Binding Lectin