title: [Induction of osteointegration of rabbit mandibular central fissure with guided tissue regeneration]
abstract: OBJECTIVE:To observe the effect of guided tissue regeneration (GTR) on induction of ostegenesis in developmental bone clefts,and provide a basis for the use of GTR to repair bony clefts in cleft lip and palate patients.METHODS:The e-PTFE membrane was placed on the labial and lingual sides of the rabbit mandibular central fissure.A radiological and pathological study was performed to determine the healing of the fissure integration.RESULTS:The results showed that the bony cleft was completely integrated 4 weeks after placement of the barrier membrane.CONCLUSION:GTR is an effective approach to reconstruct bony cleft,and is likely to be used in repair of alveolar cleft and cleft palate.
authors.affiliation: Affiliated Hospital of Stomatology,Shandong Medical University.Jinan 250012, Shandong province, China.
authors.forename: X
authors.initials: X
authors.lastname: Xu
authors.forename: P S
authors.initials: PS
authors.lastname: Yang
authors.forename: Y
authors.initials: Y
authors.lastname: Ma
authors.forename: S Z
authors.initials: SZ
authors.lastname: Sun
authors.forename: Q
authors.initials: Q
authors.lastname: Li
authors.forename: J T
authors.initials: JT
authors.lastname: Wang