Structural properties of cyclic peptides containing cis- or trans-2-aminocyclohexane carboxylic acid.
A series of cyclic peptides containing either cis- or trans-2-aminocyclohexane carboxylic acid as mimics for L-proline has been synthesized and their structural properties have been investigated using NMR and MD methods.
Strijowski
Ulf
U
University of Bielefeld, Department of Chemistry, Organic and Bioorganic Chemistry, 33501 Bielefeld, Germany.
Sewald
Norbert
N
D003509:Cyclohexanecarboxylic Acids / Q000737:chemistry*; D003514:Cyclohexylamines / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D010456:Peptides, Cyclic / Q000737:chemistry*; D011392:Proline / Q000031:analogs & derivatives; D011487:Protein Conformation
D003509:Cyclohexanecarboxylic Acids; D003514:Cyclohexylamines; D010456:Peptides, Cyclic; C103271:2-aminocyclohexanecarboxylic acid; D011392:Proline