title: Prevalence of right bundle-branch block and right precordial ST-segment elevation (Brugada-type electrocardiogram) in Japanese children.
abstract: BACKGROUND
  The prevalence of Brugada-type electrocardiogram (ECG) in schoolchildren remains unclear. This study aimed to further investigate this condition.
  
  
  RESULTS
  We studied the prevalence of Brugada-type ECG in 20,387 children (10,434 males and 9,953 females, 9.7 +/- 3.2 [SD] years old) during a school health examination in Kanagawa Prefecture, Japan, in 2002. We considered right bundle-branch block and ST-segment elevation of the J point of > or =0.1 mV in leads V1 through V3 as Brugada-like ECG, and an ECG was considered to be Brugada-type when the 12-lead ECG fully meet the criteria for the Brugada syndrome as recently published in a consensus report. Only 2 children (0.0098%, 95% confidence interval (CI): 0 to 0.023%) completely conformed to the criteria for Brugada-type ECG. Brugada-like ECG was found in 11 (10 male) of 20,387 children (0.054%, 95% CI: 0.022 to 0.086%). The prevalence in males was significantly higher than that in females, even in children (0.096% vs 0.010%, p=0.012). Stratified according to age, there was tendency for the prevalence of Brugada-like ECG to increase up to puberty (first graders, 0.01%; fourth graders, 0.05%; seventh graders, 0.08%; tenth graders, 0.23%; p=0.068).
  
  
  CONCLUSIONS
  The prevalence of Brugada-type ECG in Japanese children was much lower than that reported in the adult population.
authors.affiliation: Second Department of Internal Medicine, Yokohama City University School of Medicine, Japan.
authors.forename: Yohei
authors.initials: Y
authors.lastname: Yamakawa
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Uchino
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Mochida
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Ebina
authors.forename: Shinichi
authors.initials: S
authors.lastname: Sumita
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Kohei
authors.initials: K
authors.lastname: Matsushita
authors.forename: Katsumi
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Ohkusu
authors.forename: Takashi
authors.initials: T
authors.lastname: Nishizawa
authors.forename: Kiyohiro
authors.initials: K
authors.lastname: Takigiku
authors.forename: Mari
authors.initials: M
authors.lastname: Iwamoto
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kimura
authors.forename: Satoshi
authors.initials: S
authors.lastname: Umemura
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002037:Bundle-Branch Block / Q000453:epidemiology* / Q000235:genetics; D002648:Child; D004562:Electrocardiography; D005192:Family Health; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008403:Mass Screening; D015995:Prevalence; D013577:Syndrome