title: Gibberellic acid production by free and immobilized cells in different culture systems.
abstract: Gibberellic acid production was studied in different fermentation systems. Free and immobilized cells of Gibberella fujikuroi cultures in shake-flask, stirred and fixed-bed reactors were evaluated for the production of gibberellic acid (GA3). Gibberellic acid production with free cells cultured in a stirred reactor reached 0.206 g/L and a yield of 0.078 g of GA3/g biomass.
authors.affiliation: Bioprocess Department, Unit of Biotechnology (UPIBI), National Polytechnic Institute, Ave. Acueducto s/n, La Laguna, Ticomán, 07340 Mexico, D.F. eduran@acei.upibi.ipn.mx
authors.forename: Enrique
authors.initials: E
authors.lastname: Durán-Páramo
authors.forename: Héctor
authors.initials: H
authors.lastname: Molina-Jiménez
authors.forename: Marco A
authors.initials: MA
authors.lastname: Brito-Arias
authors.forename: Fabián
authors.initials: F
authors.lastname: Robles-Martínez
mesh_terms: D019149:Bioreactors; D001709:Biotechnology / Q000379:methods*; D018929:Cell Culture Techniques / Q000379:methods*; D002455:Cell Division; D018914:Cells, Immobilized; D003469:Culture; D003470:Culture Media; D005285:Fermentation; D005874:Gibberella / Q000378:metabolism; D005875:Gibberellins / Q000096:biosynthesis*; D013997:Time Factors
chemical_list: D003470:Culture Media; D005875:Gibberellins; C007842:gibberellic acid