Visceral hypersensitivity in noncardiac chest pain.
Visceral hypersensitivity is a common cause of NCCP. Mechanoreceptors appear to be important in the pathophysiology of NCCP, although chemoreceptors also appear to play a significant role. The processing of visceral information and possibly the development of central sensitization may be important in NCCP, although the pathophysiology of NCCPremains poorly understood.
Lembo
Anthony J
AJ
Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Hospital, Dana 501, 330 Brookline Avenue, Boston, MA 02215, USA. alembo@caregroup.harvard.edu
D002637:Chest Pain / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D006930:Hyperalgesia / Q000503:physiopathology*; D014781:Viscera / Q000503:physiopathology*