title: Usefulness of 201Tl and 99mTc MIBI scintigraphy in a case of oncogenic osteomalacia.
abstract: A 45-year-old male was admitted with difficulty in walking due to leg pain. At the time of the first visit, a reduced serum phosphorus concentration and an increased serum alkaline phosphatase concentration of unknown etiology were observed. Either a whole body bone scintigraphy or CT of the neck, chest and abdominal region did not reveal any underlying disease. However both the whole body 201Tl scintigraphy and 99mTc MIBI SPECT showed accumulation in the right knee region, and a small tumor was detected by MRI examination. After a diagnosis of oncogenic osteomalacia due to this tumor was determined the tumor was surgically removed, and turned out to be a hemangiopericytoma. By removal of the tumor, either the symptoms or the laboratory data were improved significantly. In this case, both 201Tl scintigraphy and 99mTc scintigraphy MIBI were useful in identifying the location of the tumor which caused oncogenic osteomalacia.
authors.affiliation: Department of Radiology, Juntendo University Urayasu Hospital, Chiba, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Kimizuka
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Ozaki
authors.forename: Yukiharu
authors.initials: Y
authors.lastname: Sumi
mesh_terms: D006393:Hemangiopericytoma / Q000175:diagnosis / Q000000981:diagnostic imaging*; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D018205:Neoplasms, Adipose Tissue / Q000175:diagnosis / Q000000981:diagnostic imaging*; D010018:Osteomalacia / Q000175:diagnosis / Q000000981:diagnostic imaging*; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi; D013793:Thallium
chemical_list: D019275:Radiopharmaceuticals; C027549:thallium chloride; D017256:Technetium Tc 99m Sestamibi; D013793:Thallium