title: Case of optic nerve involvement in metastasis of a gastrointestinal stromal tumor.
abstract: BACKGROUND
  The gastrointestinal stromal tumor (GIST) belongs to the leiomyosarcoma or leiomyoma group, and metastasis of leiomyosarcoma to the orbit is extremely rare. The most common sign of the metastasis of leiomyosarcoma to the orbit is proptosis; the primary lesion is usually found in skin or soft tissue.
  
  
  METHODS
  A 60-year-old man, who had a history of multiple metastases of GIST, suffered sudden unilateral blindness.
  
  
  METHODS
  His history and computed tomographic scans suggested that the lesion was a metastasis of GIST to the cavernous sinus around the root of the optic nerve.
  
  
  CONCLUSIONS
  To the best of our knowledge, this is the first case of metastasis of GIST to the orbit.
authors.affiliation: Division of Ophthalmology, Tokyo Metropolitan Geriatric Center, Tokyo, Japan. kakiyama-tky@umin.ac.jp
authors.forename: Kazuhide
authors.initials: K
authors.lastname: Akiyama
authors.forename: Jiro
authors.initials: J
authors.lastname: Numaga
authors.forename: Fumie
authors.initials: F
authors.lastname: Kagaya
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Takazawa
authors.forename: Shigenobu
authors.initials: S
authors.lastname: Suzuki
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Koseki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kato
authors.forename: Toshikatsu
authors.initials: T
authors.lastname: Kaburaki
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Kawashima
mesh_terms: D017809:Fatal Outcome; D006801:Humans; D007414:Intestinal Neoplasms / Q000473:pathology*; D007421:Intestine, Small / Q000473:pathology; D007890:Leiomyosarcoma / Q000000981:diagnostic imaging / Q000556:secondary*; D008113:Liver Neoplasms / Q000556:secondary*; D008161:Lumbosacral Region / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D019574:Optic Nerve Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D013125:Spinal Neoplasms / Q000556:secondary*; D014057:Tomography, X-Ray Computed