title: [Clinical study on the treatment of severe acute pancreatitis by integrated traditional Chinese medicine and Western medicine].
abstract: OBJECTIVE
  To sum up clinical experiences and formulate a new treatment program for the effective managment of severe acute pancreatitis(SAP) by integrated TCM and western medicine.
  
  
  METHODS
  The therapeutic regimens and end results of 1376 cases of SAP in three periods were reviewed and analyzed. Period I (1980-1990) was characterized by early surgical intervention supplemented with integrated traditional Chinese and western medical therapy, period II (1991-1993) by integrated traditional Chinese and western medical therapy supplemented with surgery for early complications, and period III (1994-2003) by integrated traditional Chinese and western medical therapy supplemented with surgery for local infectious complications at a late stage in the course of disease.
  
  
  RESULTS
  With use of integrated traditional Chinese and western medical therapy in the treatment of SAP, the proportion of surgical operation and the case-fatality rate kept declining in the three consecutive periods, the proportions of operation being 77.59%, 54.54% and 19.38%, and the case-fatality rates being 40.52%, 17.17% and 10.77%, respectively.
  
  
  CONCLUSIONS
  Integrated TCM and western medicine is effective for most SAP cases, and surgery is indicated mainly for late complications such as necrotizing infection. Early surgery should be handled with more circumspection and strictness in most of the patients with SAP.
authors.affiliation: Department of Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Xu-bao
authors.initials: XB
authors.lastname: Liu
authors.forename: Jun-ming
authors.initials: JM
authors.lastname: Jiang
authors.forename: Zong-wen
authors.initials: ZW
authors.lastname: Huang
authors.forename: Bo-le
authors.initials: BL
authors.lastname: Tian
authors.forename: Wei-ming
authors.initials: WM
authors.lastname: Hu
authors.forename: Qing
authors.initials: Q
authors.lastname: Xia
authors.forename: Guang-yuan
authors.initials: GY
authors.lastname: Chen
authors.forename: Quan-sheng
authors.initials: QS
authors.lastname: Li
authors.forename: Chao-xin
authors.initials: CX
authors.lastname: Yuan
authors.forename: Chuan-xin
authors.initials: CX
authors.lastname: Luo
authors.forename: Lü-nan
authors.initials: LN
authors.lastname: Yan
authors.forename: Zhao-da
authors.initials: ZD
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D019283:Pancreatitis, Acute Necrotizing / Q000188:drug therapy / Q000401:mortality / Q000601:surgery; D008517:Phytotherapy
chemical_list: D004365:Drugs, Chinese Herbal