Crohn's-associated chronic recurrent multifocal osteomyelitis responsive to infliximab.
We report a case of chronic recurrent clavicular osteomyelitis in association with Crohn disease. Steroid therapy resulted in partial remission; however, intractable shoulder pain and an enlarging clavicular mass subsequently recurred. Infliximab therapy resulted in significant improvement in the degree of bone pain and resolution of the large sclerotic clavicular lesion.
Carpenter
Ellen
E
Inflammatory Bowel Disease Program, Section of Gastroenterology, The Children's Mercy Hospital and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA.
Jackson
Mary Anne
MA
Friesen
Craig A
CA
Scarbrough
Marc
M
Roberts
Charles C
CC
D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D002648:Child; D002908:Chronic Disease; D002968:Clavicle; D003424:Crohn Disease / Q000150:complications / Q000188:drug therapy*; D005260:Female; D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D006801:Humans; D000069285:Infliximab; D010019:Osteomyelitis / Q000150:complications / Q000188:drug therapy*; D010146:Pain / Q000188:drug therapy / Q000209:etiology
D000911:Antibodies, Monoclonal; D005765:Gastrointestinal Agents; D000069285:Infliximab