Synthesis of aryl azides and vinyl azides via proline-promoted CuI-catalyzed coupling reactions.
The coupling reaction of aryl halides or vinyl iodide with sodium azide under catalysis of CuI/L-proline works at relatively low temperature to provide aryl azides or vinyl azides in good to excellent yields.
Zhu
Wei
W
Department of Chemistry, Fudan University, Shanghai 200433, China.
Ma
Dawei
D
D001386:Azides / Q000138:chemical synthesis*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000737:chemistry; D007454:Iodides / Q000737:chemistry*; D008956:Models, Chemical; D011392:Proline / Q000737:chemistry*; D019810:Sodium Azide / Q000737:chemistry; D014753:Vinyl Compounds / Q000737:chemistry*
D001386:Azides; D006841:Hydrocarbons, Aromatic; D006846:Hydrocarbons, Halogenated; D007454:Iodides; D014753:Vinyl Compounds; D003300:Copper; C073870:cuprous iodide; D019810:Sodium Azide; D011392:Proline