title: Health-related quality of life and disability in survivors of multiple trauma one year after intensive care unit discharge.
abstract: OBJECTIVE
  To evaluate health-related quality of life and disability in multiple-trauma patients requiring intensive care unit management.
  
  
  METHODS
  A total of 87 survivors of multiple trauma, with a median age of 31 yrs and a median Injury Severity Score of 22, were enrolled in the present study. The Nottingham Health Profile, Glasgow Outcome Scale, and Rosser Disability Scale were used to assess the functional consequences of trauma 1 yr after intensive care unit discharge.
  
  
  RESULTS
  A total of 64 of 87 patients had a problem in at least one of the six domains related to subjective health status. The most prevalent complaint was related to somatic subdimensions, but emotional functioning was also affected. Nottingham Health Profile part 2 showed that 63 of the survivors experienced problems in at least one of the daily activities. Of particular importance, inability to work was reported by 47% of the patients. Fifty-nine percent experienced moderate-to-severe disability as evaluated by Glasgow Outcome Scale and Rosser Disability Scale. High aggregate injury severity score along with severe head trauma were independent predictors of poor health-related quality of life and disability.
  
  
  CONCLUSIONS
  The majority of survivors of major trauma exhibit considerable levels of disability and impairment in health-related quality of life. Global injury severity score and degree of brain trauma determine functional limitations. This information may help in organizing long-term rehabilitation of multiple-trauma patients.
authors.affiliation: Department of Critical Care Medicine, Evangelismos Hospital, Athens, Greece.
authors.forename: Ioanna
authors.initials: I
authors.lastname: Dimopoulou
authors.forename: Anastasia
authors.initials: A
authors.lastname: Anthi
authors.forename: Zafiria
authors.initials: Z
authors.lastname: Mastora
authors.forename: Maria
authors.initials: M
authors.lastname: Theodorakopoulou
authors.forename: Alexandros
authors.initials: A
authors.lastname: Konstandinidis
authors.forename: Evangelos
authors.initials: E
authors.lastname: Evangelou
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Mandragos
authors.forename: Charis
authors.initials: C
authors.lastname: Roussos
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001930:Brain Injuries / Q000534:rehabilitation; D004185:Disability Evaluation; D006233:Persons with Disabilities / Q000534:rehabilitation; D005260:Female; D006304:Health Status; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D009104:Multiple Trauma / Q000534:rehabilitation*; D011446:Prospective Studies; D011788:Quality of Life; D017741:Survivors; D015599:Trauma Severity Indices