Anaplastic thyroid carcinoma with destructive thyrotoxicosis in a patient with preexisting multinodular goiter.
Presentation of anaplastic thyroid carcinoma with thyrotoxicosis is extremely rare and its occurrence in a patient with Wegener's granulomatosis has not been reported previously. We describe an elderly lady with Wegener's granulomatosis who developed a rapidly growing anaplastic thyroid carcinoma in a preexisting multinodular goiter and discuss the mechanism of thyrotoxicosis in this patient.
Villa
Michael L
ML
Department of Medicine, National University Hospital, Singapore.
Mukherjee
J J
JJ
Tran
Nam Q
NQ
Cheah
W K
WK
Howe
H S
HS
Lee
K O
KO
D000368:Aged; D002277:Carcinoma / Q000150:complications* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006044:Goiter, Nodular / Q000150:complications*; D014890:Granulomatosis with Polyangiitis / Q000150:complications; D006801:Humans; D013964:Thyroid Neoplasms / Q000150:complications*; D013971:Thyrotoxicosis / Q000209:etiology*