Recurrent solitary fibrous tumor of the pleura with malignant transformation.
Recurrent solitary fibrous tumor of the pleura with malignant progression occurs rarely. We report a case of solitary fibrous tumor of the pleura in an 85-year-old white woman that recurred 4 times during a span of 10 years and subsequently underwent malignant transformation. The accurate diagnosis of solitary fibrous tumor is aided by ancillary techniques, such as immunohistochemical staining; however, with malignant transformation, such tools may be of limited value. Long-term clinical follow-up is recommended for all patients with solitary fibrous tumor because of the potential adverse biological behavior of this tumor, which may lead to repeated recurrences and/or malignant transformation.
Kanthan
Rani
R
Department of Pathology, Royal University Hospital, Saskatoon, Saskatchewan, Canada. inarkanth@shaw.ca
Torkian
Bahman
B
D000199:Actins / Q000032:analysis; D000368:Aged; D000369:Aged, 80 and over; D018952:Antigens, CD34 / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D018450:Disease Progression; D005260:Female; D005350:Fibroma / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007633:Keratins / Q000032:analysis; D008654:Mesothelioma / Q000175:diagnosis; D008940:Mitotic Index; D009364:Neoplasm Recurrence, Local; D010997:Pleural Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D009418:S100 Proteins / Q000032:analysis; D012509:Sarcoma / Q000175:diagnosis; D035441:Thoracic Wall / Q000473:pathology
D000199:Actins; D018952:Antigens, CD34; D014408:Biomarkers, Tumor; D009418:S100 Proteins; D007633:Keratins