[Clinical and neurophysiological aspects of epilepsy with photosensitivity].
Using mapping EEG with dipole source location, transcranial magnetic stimulation (TMS), and visual evoked potential (VEP), clinico-neurophysiological analysis of photosensitivity was carried out in 7 patients with different types of epilepsy. In all the patients, an increase of visual response amplitude in VEP assessment and location of photogenic and eye-closing spike activity was observed in parietal and occipital areas that suggested a significant role of the striate and para striate cortex, along with primary projection cortex, in photosensitivity. Although motor cortex excitability by TMS causes hypersynchronization of the background activity and increase of slow wave discharge on the EEG after TMS. TMS is supposed to cause an activation of antiepileptic system.
Karlov
V A
VA
Dondov
B
B
Gnezditskiĭ
V V
VV
Savitskaia
N V
NV
Andreeva
O V
OV
D000293:Adolescent; D000328:Adult; D004569:Electroencephalography; D020195:Epilepsy, Reflex / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D005074:Evoked Potentials, Visual / Q000502:physiology; D005260:Female; D006801:Humans; D008280:Magnetics / Q000295:instrumentation; D008297:Male; D012720:Severity of Illness Index; D012886:Skull