Case of optic nerve involvement in metastasis of a gastrointestinal stromal tumor.
BACKGROUND
The gastrointestinal stromal tumor (GIST) belongs to the leiomyosarcoma or leiomyoma group, and metastasis of leiomyosarcoma to the orbit is extremely rare. The most common sign of the metastasis of leiomyosarcoma to the orbit is proptosis; the primary lesion is usually found in skin or soft tissue.


METHODS
A 60-year-old man, who had a history of multiple metastases of GIST, suffered sudden unilateral blindness.


METHODS
His history and computed tomographic scans suggested that the lesion was a metastasis of GIST to the cavernous sinus around the root of the optic nerve.


CONCLUSIONS
To the best of our knowledge, this is the first case of metastasis of GIST to the orbit.
Akiyama
Kazuhide
K
Division of Ophthalmology, Tokyo Metropolitan Geriatric Center, Tokyo, Japan. kakiyama-tky@umin.ac.jp
Numaga
Jiro
J
Kagaya
Fumie
F
Takazawa
Yutaka
Y
Suzuki
Shigenobu
S
Koseki
Nobuyuki
N
Kato
Satoshi
S
Kaburaki
Toshikatsu
T
Kawashima
Hidetoshi
H
D017809:Fatal Outcome; D006801:Humans; D007414:Intestinal Neoplasms / Q000473:pathology*; D007421:Intestine, Small / Q000473:pathology; D007890:Leiomyosarcoma / Q000000981:diagnostic imaging / Q000556:secondary*; D008113:Liver Neoplasms / Q000556:secondary*; D008161:Lumbosacral Region / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D019574:Optic Nerve Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D013125:Spinal Neoplasms / Q000556:secondary*; D014057:Tomography, X-Ray Computed