[The in vitro comparison of platelet induced ACC-M cell adhesion with and without Aspirin]
ObJECTIVE:Observation the affection of aspirin to adhesion of highly metastatic salivary adenoid cystic carcinoma(ACC-M) cell induced by platelet.METHODS:Adhesive ratios of ACC-M cell induced by platelet with or without aspirin were measured.RESULTS:After the addition of platelet rich plasma(PRP),adhesive ratio of ACC-M cell increased significantly (P<0.01). The treatment with aspirin after addition of PRP led to a nonsignificant increase of adhesive ratio (P>0.05).The reduction of adhesive ratio by aspirin was found dosage independent within concentration  range of 0.01-0.25g/L of aspirin. CONCLUSION:Adhesion of ACC-M cell was raised by added platelet.Addition of aspirin,platelet induced adhesion of ACC-M cell was inhibited significantly.
Gu
Z Y
ZY
Department of Oral & Maxillofacial Surgery,School of Stomatology,Shanghai Second Medical University. Shanghai 200011,China.
Qiu
W L
WL
He
R G
RG
Zhang
Z Y
ZY
Zhou
X J
XJ