Cytosine-substituted metalloporphyrins: receptors for recognition of nucleotides in ion-selective electrodes.
A new series of cytosine-substituted metalloporphyrin conjugates (containing Co(II) and Zn(II) as the coordinated metals) were designed and investigated as nucleotide receptors in PVC-membrane-based ion-selective electrodes under neutral conditions. The potentiometric results indicate that these systems, in particular the Co(II)-containing complex, may be potentially useful sensors for complementary nucleotide substrates in the presence of 10 mol% tridodecylmethylammonium chloride (K(Pot.)(5'-GMP/5'-AMP)= 0.045).
Král
Vladimír
V
Department of Analytical Chemistry, Institute of Chemical Technology, 16628 Prague 6, Technická 5, Czech Republic. vladimir.kral@vscht.cz
Shishkanova
Tatiana V
TV
Sessler
Jonathan L
JL
Brown
Christopher T
CT
D015374:Biosensing Techniques; D003596:Cytosine / Q000737:chemistry*; D004566:Electrodes; D007477:Ions; D008665:Metalloporphyrins / Q000737:chemistry*; D015394:Molecular Structure; D009711:Nucleotides / Q000378:metabolism*; D011143:Polyvinyl Chloride / Q000737:chemistry; D011199:Potentiometry; D000644:Quaternary Ammonium Compounds / Q000737:chemistry / Q000494:pharmacology
D007477:Ions; D008665:Metalloporphyrins; D009711:Nucleotides; D000644:Quaternary Ammonium Compounds; C009543:tridodecylmethylammonium; D003596:Cytosine; D011143:Polyvinyl Chloride