title: An efficient route to novel 4,5-di- and 2,4,5-tri substituted imidazoles from imidazo[1,5-a]-1,3,5-triazine (5,8-diaza-7,9-dideazapurine) derivatives.
abstract: Two new types of imidazole derivatives: N-(2-R1-5-R2-1H-imidazol-4-yl) thioureas 7a-g and N-(2-R1-5-R2-1H-imidazol-4-yl) formamides 8b,c,g were obtained in high yields by the hydrolytic degradation of 6-R1-8-R2-2-thioxo-2,3-dihydroimidazo[1,5-a]-1,3,5-triazin-4(1H)-ones 5a-g and 6-R1-8-R2-imidazo[1,5-a]-1,3,5-triazin-4(3H)-ones 6b,c,d, respectively. The tautomeric preferences of the new imidazoles were determined.
authors.affiliation: Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland. bogolan@ibch.poznan.pl
authors.forename: Bozenna
authors.initials: B
authors.lastname: Golankiewicz
authors.forename: Piotr
authors.initials: P
authors.lastname: Januszczyk
authors.forename: Joanna
authors.initials: J
authors.lastname: Zeidler
authors.forename: Mariusz
authors.initials: M
authors.lastname: Popenda
mesh_terms: D007093:Imidazoles / Q000138:chemical synthesis*; D011687:Purines / Q000737:chemistry*
chemical_list: D007093:Imidazoles; D011687:Purines