title: Applications of bispectral index monitoring in the pediatric intensive care unit.
abstract: The bispectral index (BIS) monitor is an electroencephalographic recording device that generates a single numeric value. It has traditionally been used to measure anesthetic depth and avoid awareness in the operating room setting. In this report, the authors present different scenarios in the pediatric intensive care unit that demonstrate the potential applications of the BIS monitor outside of the operating room setting. The scenarios presented include use of the BIS monitor during titration of barbiturate coma, procedural sedation, sedation assessment during mechanical ventilation, and sedation while administering potentially confounding medications. Previous reports regarding the use of the BIS monitor in such scenarios and potential future applications are reviewed
authors.affiliation: Department of Child Health, University of Missouri, Columbia, 65212,USA.
authors.forename: Ryan J
authors.initials: RJ
authors.lastname: Grindstaff
authors.forename: Joseph D
authors.initials: JD
authors.lastname: Tobias
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001856:Bone Marrow Examination / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D016292:Procedural Sedation / Q000009:adverse effects; D003422:Critical Care / Q000379:methods*; D004347:Drug Interactions; D016903:Drug Monitoring / Q000379:methods; D064420:Drug-Related Side Effects and Adverse Reactions; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D006353:Heart-Assist Devices / Q000009:adverse effects; D006801:Humans; D007223:Infant; D015278:Intensive Care Units, Pediatric; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods*; D009104:Multiple Trauma / Q000628:therapy; D018579:Patient Selection; D011182:Postoperative Care / Q000379:methods; D012121:Respiration, Artificial / Q000009:adverse effects; D012815:Signal Processing, Computer-Assisted; D013224:Status Asthmaticus / Q000628:therapy