[Experimental study of radiosensitization of buthionine sulffoximine (BSO) on Acc-2 transplanted tumor]
OBJECTIVE:The effect of radiosensitization of BSO on Acc-2 transplanted tumor was studied in vivo.METHODS: There were four groups in this experiment:control group,radiation group and BSO+radiation group.The drug dose of BSO is 5mmol/kg and the radiation dose was 10Gy. RESULTS:The result demonstrated that the tumor inhibitive rate was 8.5%,12.6% and 45.37% respectively compared with control group. CONCLUSION: BSO has radiosensitizative effect on Acc-2 transplanted tumor.
Wan
G Y
GY
Department of Oral and Maxillofacial Surgery, School of Stomatology, Shanghai Second Medical University. Shanghai 200011, China.
Lin
G C
GC
Wang
Z H
ZH
Chen
W T
WT