Cytomegalovirus Retinitis in infancy.
OBJECTIVE
To describe the presentation of cytomegalovirus retinitis (CMVR) in a series of infants.


METHODS
Immunocompromised infants with either HIV or systemic cytomegalovirus (CMV) were examined for CMVR. Ocular involvement was recorded and monitored by digital imaging.


RESULTS
Five infants were detected to have CMVR. All the infants demonstrated changes within the macula. One infant progressed from a fine granular pattern to fulminant CMVR.


CONCLUSIONS
Infants under a year with CMVR have a predilection for the disease to present at the macula, in contrast to the presentation in adults, which tends to involve more peripheral parts of the retina.
Wren
S M E
SM
Western Eye Hospital, London, UK.
Fielder
A R
AR
Bethell
D
D
Lyall
E G H
EG
Tudor-Williams
G
G
Cocker
K D
KD
Mitchell
S M
SM
D017088:AIDS-Related Opportunistic Infections / Q000276:immunology / Q000473:pathology / Q000821:virology; D017726:Cytomegalovirus Retinitis / Q000276:immunology / Q000473:pathology* / Q000821:virology; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D007231:Infant, Newborn; D008266:Macula Lutea / Q000473:pathology; D008297:Male; D019562:Viral Load