title: Survey of cannabis use in patients with amyotrophic lateral sclerosis.
abstract: Cannabis (marijuana) has been proposed as treatment for a widening spectrum of medical conditions and has many properties that may be applicable to the management of amyotrophic lateral sclerosis (ALS). This study is the first, anonymous survey of persons with ALS regarding the use of cannabis. There were 131 respondents, 13 of whom reported using cannabis in the last 12 months. Although the small number of people with ALS that reported using cannabis limits the interpretation of the survey findings, the results indicate that cannabis may be moderately effective at reducing symptoms of appetite loss, depression, pain, spasticity, and drooling. Cannabis was reported ineffective in reducing difficulties with speech and swallowing, and sexual dysfunction. The longest relief was reported for depression (approximately two to three hours).
authors.affiliation: Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
authors.forename: Dagmar
authors.initials: D
authors.lastname: Amtmann
authors.forename: Patrick
authors.initials: P
authors.lastname: Weydt
authors.forename: Kurt L
authors.initials: KL
authors.lastname: Johnson
authors.forename: Mark P
authors.initials: MP
authors.lastname: Jensen
authors.forename: Gregory T
authors.initials: GT
authors.lastname: Carter
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000690:Amyotrophic Lateral Sclerosis / Q000188:drug therapy*; D002188:Cannabis; D005260:Female; D006801:Humans; D008297:Male; D008385:Marijuana Smoking; D008875:Middle Aged; D010166:Palliative Care; D008517:Phytotherapy; D028321:Plant Preparations / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D028321:Plant Preparations