Molecular genetic approaches to studying fertilization in model systems.
In a wide range of experimental systems, a variety of both forward and reverse genetic approaches are becoming available for the study of the molecules involved in fertilization. An integration of these methods with the antibody-based and biochemical studies traditionally used in fertilization research is enabling rapid advancements in our understanding of this process. We highlight some of the recent advances resulting from these genetic methods and their applications in these systems.
Geldziler
Brian
B
Waksman Institute, Rutgers University, Piscataway, New Jersey 08854, USA.
Kadandale
Pavan
P
Singson
Andrew
A
D000818:Animals; D030801:Animals, Genetically Modified; D005260:Female; D005306:Fertilization / Q000235:genetics / Q000502:physiology*; D005307:Fertilization in Vitro / Q000379:methods; D015870:Gene Expression; D015723:Gene Library; D023281:Genomics; D005838:Genotype; D008297:Male; D023421:Models, Animal; D016296:Mutagenesis; D010641:Phenotype