[Current concepts and recent developments of laser ablation in tumor therapy].
OBJECTIVE
The purpose of this paper is to present technical innovations and clinical results of percutaneous interventional laser ablation of tumors using new techniques. METHODS; Laser ablation was performed in 182 patients (liver tumors: 131, non hepatic tumors-bone, lung, others: 51) after interdisciplinary consensus was obtained. The procedure was done using a combination of imaging modalities (CT/MRI, CT/US) or only closed high field MRI (1.5 T). All patients received an MRI-scan immediately after laser ablation.


RESULTS
In 90.9% of the patients with liver tumors, a complete ablation was achieved. Major events occurred in 5.4%. The technical success rate of laser ablation in non-hepatic tumors was high, clinical results differed depending on the treated organ.


CONCLUSIONS
The treatment of tumors of the liver and other organs up to 5 cm by laser ablation was a safe procedure with a low rate of complications and side effects. Image guidance by MRI is advantageous for precise tumor visualization in all dimensions, therapy monitoring, and control of laser ablation results.
Stroszczynski
C
C
Klinik für Strahlenheilkunde der Charité, Campus-Virchow-Klinikum und Campus Buch-Medizinische Fakultät der Humboldt-Universität zu Berlin. stros@charite.de
Gaffke
G
G
Gnauck
M
M
Puls
R
R
Hosten
N
N
Speck
U
U
Ricke
J
J
Oettle
H
H
Hohenberger
P
P
Felix
R
R
D000328:Adult; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods* / Q000639:trends; D053685:Laser Therapy / Q000379:methods* / Q000639:trends; D008113:Liver Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000628:therapy*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000628:therapy; D009928:Organ Specificity; D013813:Therapy, Computer-Assisted / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome; D014463:Ultrasonography / Q000379:methods*