Functional obstruction: the renal pelvis rules.
Failure in the peristaltic mechanism that conducts urine from the kidney to the bladder can lead to hydronephrosis, a common birth defect associated with obstructive nephropathy. New animal models reveal molecular pathways important for peristalsis and point to the central role of the renal pelvis in urine transport.
Mendelsohn
Cathy
C
Department of Urology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA. clm20@columbia.edu
D019703:Calcineurin / Q000494:pharmacology*; D006133:Growth Substances / Q000494:pharmacology*; D006801:Humans; D007668:Kidney / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D014513:Ureter / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology
D006133:Growth Substances; D019703:Calcineurin