High variety of different simian T-cell leukemia virus type 1 strains in chimpanzees (Pan troglodytes verus) of the Taï National Park, Côte d'Ivoire.
We found human T-cell leukemia virus type 1- and simian T-cell leukemia virus type 1 (STLV-1)-related infections in 5 of 10 chimpanzees originating from three groups of wild chimpanzees. The new virus isolates showed a surprising heterogeneity not only in comparison to STLV-1 described previously in other primate species but also between the different chimpanzee groups, within a group, or even between strains isolated from an individual animal. The interdisciplinary combination of virology, molecular epidemiology, and long-term behavioral studies suggests that the primary route of infection might be interspecies transmission from other primates, such as red colobus monkeys, that are hunted and consumed by chimpanzees.
Leendertz
Fabian H
FH
Division of Retrovirology, Robert Koch Institute, D-13353 Berlin, Germany.
Junglen
Sandra
S
Boesch
Christophe
C
Formenty
Pierre
P
Couacy-Hymann
Emmanuel
E
Courgnaud
Valerie
V
Pauli
Georg
G
Ellerbrok
Heinz
H
D000818:Animals; D000835:Animals, Wild / Q000821:virology; D018420:Ape Diseases / Q000635:transmission / Q000821:virology*; D001483:Base Sequence; D003104:Colobus / Q000821:virology; D007560:Cote d'Ivoire; D004279:DNA, Viral / Q000235:genetics; D006800:Deltaretrovirus Infections / Q000635:transmission / Q000662:veterinary / Q000821:virology; D019143:Evolution, Molecular; D005260:Female; D014644:Genetic Variation; D015490:HTLV-I Infections / Q000635:transmission / Q000662:veterinary / Q000821:virology; D015368:Human T-lymphotropic virus 1 / Q000235:genetics / Q000302:isolation & purification; D008297:Male; D002679:Pan troglodytes / Q000821:virology*; D010802:Phylogeny; D015303:Simian T-lymphotropic virus 1 / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification* / Q000472:pathogenicity; D013045:Species Specificity
D004279:DNA, Viral