A case of HIV-associated facial lipoatrophy treated with 1000-cs liquid injectable silicone.
BACKGROUND
Patients infected with the HIV may experience HIV-associated lipodystrophy, a symptom of which is facial lipoatrophy, a dramatic loss of subcutaneous facial tissue. This visible manifestation of HIV infection causes significant psychosocial pain for patients and has been associated with impaired compliance with medical regimens.


OBJECTIVE
To improve the appearance of facial lipoatrophy in a safe, long-lasting, expeditious, and relatively economical manner.


METHODS
An HIV-associated lipodystrophy patient with facial lipoatrophy underwent multiple sessions of soft-tissue augmentation therapy with liquid injectable silicone (LIS) using the microdroplet serial puncture technique.


RESULTS
Administration of LIS by the microdroplet serial puncture technique produced satisfactory improvement of areas of facial atrophy. The treatment time is limited, the patient discomfort and morbidity are minimal, and results are long lasting. Patients report significant satisfaction with treatment.


CONCLUSIONS
LIS administered by the microdroplet serial puncture technique is a safe and effective method for treating HIV-associated facial lipoatrophy and compares favorably with other methods of tissue augmentation.
Orentreich
David
D
Orentreich Medical Group, LLP, Orentreich Foundation for the Advancement of Science Inc., 910 Fifth Avenue, New York, NY 10021, USA.
Leone
Anna-Sophia
AS
D001672:Biocompatible Materials / Q000008:administration & dosage*; D004129:Dimethylpolysiloxanes / Q000008:administration & dosage*; D005145:Face; D039682:HIV-Associated Lipodystrophy Syndrome / Q000628:therapy*; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D008875:Middle Aged; D012828:Silicones / Q000008:administration & dosage*; D016896:Treatment Outcome
D001672:Biocompatible Materials; D004129:Dimethylpolysiloxanes; D012828:Silicones; C013830:baysilon