title: A domino ring-opening/epoxidation of 1,2-dioxines.
abstract: When allowed to react with alkaline hydrogen peroxide, monocyclic 1,2-dioxines ring-open to their isomeric gamma-hydroxyenone intermediates which are rapidly epoxidized to afford trans-4-hydroxy-2,3-epoxyketones in 21-81% yield. In the case of meso-1,2-dioxines, Co(II) complex catalyzed asymmetric ring-opening of the 1,2-dioxine may be employed to furnish enantioenriched epoxides
authors.affiliation: Department of Chemistry, University of Adelaide, South Australia 5005, Australia.
authors.forename: Ben W
authors.initials: BW
authors.lastname: Greatrex
authors.forename: Dennis K
authors.initials: DK
authors.lastname: Taylor
authors.forename: Edward R T
authors.initials: ER
authors.lastname: Tiekink