title: Determination of bisphenol A in environmental water at ultra-low level by high-performance liquid chromatography with an effective on-line pretreatment device.
abstract: We have developed a simple HPLC method for the microanalysis of bisphenol A (BPA), which is often contained in environmental water and is known as an endocrine disrupter. HPLC coupled with electrochemical detection requires a simpler procedure of pretreatment compared to GC-MS. In this study, we analyzed BPA using molecularly imprinted polymer as an on-line pretreatment device. This polymer has molecular recognition sites and provides specific selectivity in extraction process. Due to this effect, the detection limit obtained with this HPLC was 0.36 ng/l. This method applied to environmental water and purified water samples containing 2-70 ng/l of BPA successfully. Furthermore, UV detection was performed in some actual analyses.
authors.affiliation: Department of Polymer Science and Engineering, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan.
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Watabe
authors.forename: Takuya
authors.initials: T
authors.lastname: Kondo
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Morita
authors.forename: Nobuo
authors.initials: N
authors.lastname: Tanaka
authors.forename: Jun
authors.initials: J
authors.lastname: Haginaka
authors.forename: Ken
authors.initials: K
authors.lastname: Hosoya
mesh_terms: D001559:Benzhydryl Compounds; D004785:Environmental Pollutants / Q000032:analysis*; D010636:Phenols / Q000032:analysis*; D012680:Sensitivity and Specificity; D013056:Spectrophotometry, Ultraviolet; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D004785:Environmental Pollutants; D010636:Phenols; C006780:bisphenol A; D000098826:Bisphenol A Compounds