A new catch in the SNARE.
Vesicle traffic underpins cell homeostasis, growth and development in plants. Traffic is facilitated by a superfamily of proteins known as SNAREs ( soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptors) that interact to draw vesicle and target membrane surfaces together for fusion of the bilayers. Several recent findings now indicate that plant SNAREs might not be limited to the conventional 'housekeeping' activities commonly attributed to vesicle trafficking. In the past five years, six different SNAREs have been implicated in stomatal movements, gravisensing and pathogen resistance. These proteins almost certainly do contribute to specific membrane fusion events but they are also essential for signal transduction and response. Some SNAREs can modulate the activity of non-SNARE proteins, notably ion channels. Other examples might reflect SNARE interactions with different scaffolding and structural components of the cell.
Pratelli
Réjane
R
Laboratory of Plant Physiology and Biophysics, IBLS-Plant Sciences, Bower Building, University of Glasgow, Glasgow, UK G12 8QQ.
Sutter
Jens-Uwe
JU
Blatt
Michael R
MR
D000818:Animals; D029681:Arabidopsis Proteins / Q000378:metabolism; D018745:Genome, Plant; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism*; D008954:Models, Biological; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D050600:SNARE Proteins; D015398:Signal Transduction; D033921:Vesicular Transport Proteins
D029681:Arabidopsis Proteins; D008565:Membrane Proteins; D050600:SNARE Proteins; D033921:Vesicular Transport Proteins