title: The ADVIA Centaur immunoassay system--designed for infectious disease testing.
abstract: The ability to automate immunodiagnostics testing is critical for the efficiency of clinical laboratories. For automation of Infectious Disease testing, special design considerations must be made to ensure the integrity of the testing result while at the same time delivering productivity. The ADVIA Centaur was designed with the intent of performing a complete Infectious Disease panel including HBV, HCV, and HIV markers. Features such as disposable sample tips, sample and reagent delivery verification, and clog and clog detection have been incorporated in the design for assay robustness. Productivity features deliver best in class throughput performance for the Infectious Disease assays. Moreover, the underlying technology incorporating flexible assay protocols, universal solid phases and proprietary acridinium ester technology contribute to the assay design flexibility and analytical performance of the ADVIA Centaur immunoassay system.
authors.affiliation: Bayer HealthCare LLC, Diagnostics Division, 511 Benedict Avenue, Tarrytown, NY 10591-5097, USA. david.okrongly.b@bayer.com
authors.forename: David
authors.initials: D
authors.lastname: Okrongly
mesh_terms: D015492:AIDS Serodiagnosis; D001322:Autoanalysis; D003141:Communicable Diseases / Q000175:diagnosis*; D004209:Disposable Equipment; D015483:HIV Antibodies / Q000097:blood; D006509:Hepatitis B / Q000175:diagnosis; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006526:Hepatitis C / Q000175:diagnosis; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods; D015203:Reproducibility of Results; D012409:Rubella / Q000175:diagnosis; D012680:Sensitivity and Specificity; D014123:Toxoplasmosis / Q000175:diagnosis
chemical_list: D015483:HIV Antibodies; D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies