2,5-Dialkyl cyclohexenones by Fe(CO)5-mediated carbonylation of alkenyl cyclopropanes: functional group compatibility.
The preparation of alkenyl cyclopropanes 1 with a variety of common organic functionalities is reported. These substrates were subjected to the Fe(CO)(5)-mediated carbonylation process under a CO atmosphere, leading to the formation of 2,5-disubstituted cyclohexenones 2, important intermediates for target-directed synthesis.
Taber
Douglass F
DF
Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA. taberdf@udel.edu
Joshi
Pramod V
PV
Kanai
Kazuo
K
D000475:Alkenes / Q000737:chemistry*; D002248:Carbon Monoxide / Q000737:chemistry; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D003510:Cyclohexanes / Q000138:chemical synthesis* / Q000737:chemistry; D003517:Cyclopentanes / Q000737:chemistry*; D007202:Indicators and Reagents; D007501:Iron / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry
D000475:Alkenes; D003510:Cyclohexanes; D003517:Cyclopentanes; D007202:Indicators and Reagents; D009942:Organometallic Compounds; D002248:Carbon Monoxide; D007501:Iron