[The association between infection of Epstein-Barr virus and chronic periodontitis].
OBJECTIVE
To investigate the relationship between Epstein-Barr virus (EBV) infection and chronic periodontitis.


METHODS
In 62 chronic periodontitis patients, subgingival plaque samples were collected from active periodontitis site, quiescent periodontitis site, and initial gingivitis sites of each subject. The nested polymerase chain reaction (nested-PCR) was used to determine the presence of EBV.


RESULTS
The EBV was detected in 58.0% of the samples from active periodontitis sites, which was significantly higher than that from quiescent periodontitis sites (58.0% vs 22.6%, P < 0.01) and from initial gingivitis sites (58.0% vs 19.4%, P < 0.01).


CONCLUSIONS
The results suggest that EBV infection is associated with the activity of chronic periodontitis.
Li
Ying
Y
Department of Periodontology and Oral Medicine, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou 510055, China. zjcwcums@mail.sc.cninfo.net
Zhang
Jin-cai
JC
Zhang
Yun-hui
YH
D000328:Adult; D002908:Chronic Disease; D020031:Epstein-Barr Virus Infections / Q000150:complications*; D005260:Female; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000821:virology*; D016133:Polymerase Chain Reaction