title: Do behavioral disturbances in persons with Alzheimer's disease predict caregiver depression over time?
abstract: Random effects models were used to examine the association between behavioral disturbances in persons with Alzheimer's disease (N = 90) and caregiver depressive symptoms at 2-month intervals over an 18-month period. There was substantial variability in trajectories of change in caregiver depressive symptoms over time but no systematic increase in distress despite increased severity of dementia symptoms. Total behavioral disturbances were associated with higher levels of caregiver depressive symptoms: this effect was primarily attributable to aggressive behaviors. No consistent departure from linearity was evident in the relationship between behavior and depression over time.
authors.affiliation: Stanford Center for Research in Disease Prevention, Stanford University School of Medicine, Stanford, CA, USA.
authors.forename: Suzanne C
authors.initials: SC
authors.lastname: Danhauer
authors.forename: Judith J
authors.initials: JJ
authors.lastname: McCann
authors.forename: David W
authors.initials: DW
authors.lastname: Gilley
authors.forename: Laurel A
authors.initials: LA
authors.lastname: Beckett
authors.forename: Julia L
authors.initials: JL
authors.lastname: Bienias
authors.forename: Denis A
authors.initials: DA
authors.lastname: Evans
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000523:psychology*; D017028:Caregivers / Q000523:psychology*; D003863:Depression / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology*; D008875:Middle Aged; D011446:Prospective Studies