title: Studies on tellurium-containing heterocycles. Part 22. Tellurazepine ring system: preparation of 1,5-benzotellurazepin-4-ones and their conversion into fully unsaturated 1,5-benzotellurazepines.
abstract: The treatment of o-iodopropiolanilides (12), which were easily prepared from o-iodophenylisocyanate (11) and ethynylmagnesium bromide, with sodium hydrogen telluride resulted in the intramolecular ring closure of the presumed phenyltellurol intermediates (13) to a triple bond to give the 1,5-benzotellurazepin-4-ones (14) as the sole characterized products. The obtained amides (14) were easily converted into fully unsaturated lactim 4-methoxy-1,5-benzotellurazepines (18) by treatment with trimethyloxonium tetrafluoroborate. Decomposition by thermolysis of the 4-methoxyazepinenes (18) afforded the 4-methoxyquinolines (19) with extrusion of a tellurium atom.
authors.affiliation: Faculty of Pharmaceutical Sciences, Hokuriku University, Kanagawa-machi. Kanzawa, Japan. h-sashida@hokuriku-u.ac.jp
authors.forename: Haruki
authors.initials: H
authors.lastname: Sashida
authors.forename: Hirohito
authors.initials: H
authors.lastname: Satoh
mesh_terms: D001381:Azepines / Q000138:chemical synthesis* / Q000737:chemistry; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013055:Spectrophotometry, Infrared; D013691:Tellurium / Q000737:chemistry*
chemical_list: D001381:Azepines; D007202:Indicators and Reagents; D013691:Tellurium