[Ultrasound determination of carotid artery intima media thickness in patients on dialysis and correlation with risk factors for atherosclerosis].
Atherosclerosis is significant risk factor for cardiovascular morbidity and mortality in dialysis patients. Aim of the study was ultrasound evaluation of intima media thickness on carotid arteries (as a marker of atherosclerosis), in dialysis patients and its correlation with proposed risk factors. Intima media thickness was measured in 45 dialysis patients with no signs of cardiovascular diseases (15 on peritoneal dialysis, group I, 30 on hemodialysis, group II) and 20 healthy controls. The mean carotid artery intima media thickness was significantly higher in dialysis patients than in control group. According to intima media thickness, dialysis patients were divided in group A (patient with intima media thickness less or equal 0.720 mm) and group B (intima media thickness higher then 0.720 mm). Intima media thickness in bout group was correlated with proposed risk factors. In group A there was not significant correlation of intima media thickness with risk factors. In group B significant correlation have been found between intima media thickness and LDL, VLDL cholesterol, body mass index and systolic, diastolic and mean blood pressure. Although atherosclerosis was not the only cause for cardiovascular morbidity and mortality, it has a dominant role in dialysis patients. Augmented intima media thickness could be early marker of atherosclerosis. The risk factors of great influence on intima media thickness are lipid disturbances, obesity and hypertension.
Damjanović
Tatjana
T
Center for Renal Diseases, Zvezdara University Hospital, Belgrade. damtanja@beotel.yu
Dimković
Nada
N
D001161:Arteriosclerosis / Q000209:etiology*; D002339:Carotid Arteries / Q000000981:diagnostic imaging*; D006801:Humans; D006435:Renal Dialysis / Q000009:adverse effects; D012307:Risk Factors; D017539:Tunica Intima / Q000000981:diagnostic imaging*; D014463:Ultrasonography