title: Use of an immunoglobulin G avidity test to discriminate between primary and secondary dengue virus infections.
abstract: An enzyme-linked immunosorbent assay-based immunoglobulin G (IgG) antibody avidity test was evaluated by using sera from 57 patients with acute dengue infection. Overall, 55 of 57 patients were correctly classified (27 of 27 with primary dengue and 28 of 30 with secondary dengue). We conclude that the IgG avidity test can be useful for differentiating between acute, primary, and secondary dengue infections.
authors.affiliation: Laboratório de Virologia (LIMHC-52), Instituto de Medicina Tropical de São Paulo, Brazil.
authors.forename: Vanda Akico Ueda Fick
authors.initials: VA
authors.lastname: de Souza
authors.forename: Silvana
authors.initials: S
authors.lastname: Fernandes
authors.forename: Evaldo Stanislau
authors.initials: ES
authors.lastname: Araújo
authors.forename: Adriana Fumie
authors.initials: AF
authors.lastname: Tateno
authors.forename: Olímpia M N P F
authors.initials: OM
authors.lastname: Oliveira
authors.forename: Renato Reis
authors.initials: RR
authors.lastname: Oliveira
authors.forename: Cláudio Sérgio
authors.initials: CS
authors.lastname: Pannuti
mesh_terms: D000208:Acute Disease; D000914:Antibodies, Viral / Q000097:blood / Q000276:immunology*; D000915:Antibody Affinity; D002908:Chronic Disease; D003715:Dengue / Q000175:diagnosis* / Q000276:immunology; D003716:Dengue Virus / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G