title: [Clinical study on value of severity of patient with coronary artery disease evaluated with the thrombosis in myocardial infarction risk score].
abstract: OBJECTIVE
  To explore the value of severity evaluating and outcome predicting on coronary artery disease (CAD) patients scored with the thrombosis in myocardial infarction (TIMI) risk score.
  
  
  METHODS
  All of 126 patients with CAD were enrolled in study. TIMI risk score and coronary artery angiographic in them were performed respectively. Correlativity between TIMI risk score and clinical type of CAD, narrow severity, pathological changes limits and character of coronary artery were analyzed. Difference of scores of TIMI, narrow severity, pathological changes limits and character of coronary artery were compared among stable angina (SA), unstable angina (UA), un-ST-segment elevation myocardial infarction (NSTEMI) and ST-segment elevation myocardial infarction (STEMI) respectively.
  
  
  RESULTS
  TIMI risk score significantly correlated with clinical type of CAD score, narrow severity score, pathological changes limits and character scores of coronary artery respectively (r=0.607 for narrow severity score, 0.569 for pathological changes limits score, 0.367 for pathological changes character score, all P<0.05). TIMI risk score increased company with severity of coronary artery pathological changes advancing. Significantly differences were found when TIMI risk scores were compared between SA and UA, NSTEMI and STEMI respectively as well as narrow severity scores (all P<0.05). Same
  
  
  RESULTS
  were found between UA and NSTEMI, STEMI respectively (all P<0.05). There had no significantly difference among pathological changes limits scores of SA, UA, NSTEMI, STEMI (all P>0.05). Significantly difference was found when pathological changes character scores were compared between SA and UA, NSTEMI, STEMI respectively as well as narrow severity scores (P<0.05), but contrary
  
  
  RESULTS
  were found between UA and NSTEMI, STEMI respectively (P>0.05).
  
  
  CONCLUSIONS
  TIMI risk score not only could be used to predict the possibility of heart accident, but also could be used to evaluate clinical type of CAD, narrow severity, pathological changes limits and character of coronary artery in CAD patient.
authors.affiliation: Emergency Department of Shenzhen Second People's Hospital, Shenzhen 518035, Guangdong, China.
authors.forename: Xiao-ying
authors.initials: XY
authors.lastname: Zheng
authors.forename: Xin-ke
authors.initials: XK
authors.lastname: Meng
authors.forename: Wen-guang
authors.initials: WG
authors.lastname: Li
authors.forename: Jing
authors.initials: J
authors.lastname: Yang
authors.forename: Gang
authors.initials: G
authors.lastname: Wei
authors.forename: Rui
authors.initials: R
authors.lastname: Fang
mesh_terms: D000328:Adult; D000368:Aged; D000790:Angiocardiography; D003324:Coronary Artery Disease / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D011237:Predictive Value of Tests; D012307:Risk Factors; D012720:Severity of Illness Index; D013927:Thrombosis / Q000209:etiology / Q000473:pathology*