Painful legs and moving toes syndrome associated with herpes zoster myelitis.
A 75-year-old woman developed painful legs and moving toes syndrome (PLMT) 16 months after the onset of herpes zoster (HZ) myelitis. Although the scattered extensive lesions due to HZ myelitis were observed to be eccentric near the posterior horn on MRI, these changes had disappeared upon the development of PLMT. Combined median and tibial nerve somatosensory evoked potentials demonstrated abnormal findings only in the tibial nerve stimuli, suggesting that a severe alteration occurred in the somatosensory fibers coming selectively from the lower legs. These findings suggest plasticity in the ascending somatosensory pathway including the posterior horn cells, probably involving the interneuron networks, for the lower legs may underlie the development of PLMT associated with HZ myelitis.
Ikeda
Kazuyo
K
Third Department of Internal Medicine, Kagawa University School of Medicine, 1750-1 Ikenobe, Miki-cho, Kita-gun, 761-0793 Kagawa, Japan.
Deguchi
Kazushi
K
Touge
Tetsuo
T
Sasaki
Iwao
I
Tsukaguchi
Masago
M
Shimamura
Mieko
M
Komatsu
Emi
E
Takeuchi
Hiroaki
H
Kuriyama
Shigeki
S
D000368:Aged; D005073:Evoked Potentials, Somatosensory; D005260:Female; D006562:Herpes Zoster / Q000150:complications* / Q000473:pathology; D006801:Humans; D007866:Leg; D008279:Magnetic Resonance Imaging; D009069:Movement Disorders / Q000473:pathology / Q000821:virology*; D009187:Myelitis / Q000150:complications* / Q000473:pathology / Q000821:virology*; D009473:Neuronal Plasticity; D010146:Pain / Q000473:pathology / Q000821:virology*; D013116:Spinal Cord / Q000473:pathology / Q000821:virology; D014034:Toes