Functional analysis of the role of hypoxia-inducible factor 1 in the pathogenesis of hypoxic pulmonary hypertension.
Shimoda
Larissa A
LA
Division of Pulmonary and Critical Care Medicine, Department of Medicine, The Johns Hopkinds University School of Medicine, Baltimore, Maryland 21224, USA.
Semenza
Gregg L
GL
D000818:Animals; D001794:Blood Pressure / Q000502:physiology; D019411:Clinical Laboratory Techniques; D004268:DNA-Binding Proteins / Q000502:physiology*; D006352:Heart Ventricles / Q000378:metabolism; D006400:Hematocrit; D006976:Hypertension, Pulmonary / Q000209:etiology*; D000860:Hypoxia / Q000378:metabolism*; D051793:Hypoxia-Inducible Factor 1; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D032389:Myocytes, Smooth Muscle / Q000378:metabolism; D009687:Nuclear Proteins / Q000502:physiology*; D018408:Patch-Clamp Techniques / Q000379:methods; D011651:Pulmonary Artery / Q000378:metabolism; D014157:Transcription Factors
D004268:DNA-Binding Proteins; C497443:Hif1a protein, mouse; D051793:Hypoxia-Inducible Factor 1; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D009687:Nuclear Proteins; D014157:Transcription Factors