A novel enantioselective (2Z)-alk-2-enylation of aldehydes via an allyl-transfer reaction from chiral allyl donors prepared from (+)-isomenthone.
A highly enantioselective (2Z)-alk-2-enylation of aldehydes was successfully achieved by an allyl-transfer reaction from a chiral allyl donor, which was easily obtained by separation of a diastereomeric mixture of the corresponding homoallylic alcohol gamma-adducts derived from (+)-isomenthone with alk-2-enylmagnesium chloride. [reaction: see text]
Nokami
Junzo
J
Department of Applied Chemistry, Okayama University of Science, Ridai-cho, Okayama 700-0005, Japan. nogami@dac.ous.ac.jp
Nomiyama
Kenta
K
Shafi
Siddiqi M
SM
Kataoka
Kazuhide
K