[Effect of a meal on electrocardiographic features in patients with coronary artery disease].
The aim of the study was to assess the relationship between gastric motility and extent of coronary insufficiency in males with and without stabile coronary artery disease (CAD). The study group consisted of 30 males with CAD (mean age 56 +/- 12 years) and 10 healthy males in control group (mean age 52 +/- 14 years). In both groups we performed exercise treadmill test (ETT) in interdigestive period (IP) and postprandially after ingestion of a standard meal (775 kcal) after 30 and 120 min. Gastric emptying was determined as antral area evaluated in ultrasonography before, 30 and 120 min. after meal. A period of time to ST depression > or = 1 mm, mean time of exercise, and a maximal voltage of ST depression were measured and compared between studied group of patients in t-test. In healthy individuals there was no influence of meal on ETT, thus in men in CAD group postprandially we observed shortening of time to ST depression > or = 1 mm (p < 0.001) and mean time of exercise (p < 0.001). These findings were parallel to observed enlarged gastric antral area reflecting gastric filling in postprandial period. ST depression during ETT 30 min. after meal was deeper than in interdigestive period (p < 0.001). In contrast to healthy individuals intake of standard meal in CAD group increased symptoms of coronary insufficiency during stress testing. Relationship between exercise-induced coronary insufficiency and degree of gastric filling appears as increasing of coronary insufficiency connected with gastric filling and graduate decreasing during digestion.
Orski
Jacek
J
Katedra i Klinika Chorób Wewnetrznych, Gerontologii Collegium Medicum Uniwersytetu Jagiellońskiego, Kraków.
Pawlik
Teresa
T
Bednarz
Stefan
S
Grodzicki
Tomasz
T
D000328:Adult; D003324:Coronary Artery Disease / Q000503:physiopathology*; D004063:Digestion; D004435:Eating; D004562:Electrocardiography; D005080:Exercise Test; D005746:Gastric Emptying; D006801:Humans; D008297:Male; D008875:Middle Aged; D019518:Postprandial Period