[Clinical observation of wenshen xiezhuo decoction in treating pations with chronic renal failure].
OBJECTIVE
To observe curative effect of Wenshen Xiezhuo Decoction (WSXZD) in treating pations with chronic renal failure (CRF).


METHODS
Sixty patients with CRF of deficienncy of spleen-Yang and kidney-Yang with damp pathogen and blood stasis symptom were randomly divided into the treated group and the control group, 30 in each group. Both groups were treated with low-protein diets, controlling hypertension and symptomatic treatment. And WSXZD was given additionally to the treated group. The curative effect and the changes of integral of traditional Chinese medicine (TCM) symptoms, renal function, serum calcium, serum phosphorus and ALB were observed after two months.


RESULTS
The significant and total effective rate of the treated group were higher than that of the control group (P < 0.05, P < 0.01). Compared with the control group, integral of TCM symptoms and the levels of serum phosphorus were decreased significantly, the levels of ALB were increased significantly, and renal function was improved significantly in the treated group (P < 0.05, P < 0.01).


CONCLUSIONS
The curative effect of conventional western medicine therapy plus WSXZD in treating pations with CRF of deficiency of spleen-Yang and kidney-Yang with damp pathogen and blood stasis symptom was significantly better than that of conventional western medicine therapy.
Shen
Weizeng
W
People's Hospital in Baoan District of Shenzhen, Shenzhen 518101.
Li
Junbiao
J
Wu
Xinlin
X
Liu
Benliu
B
D000293:Adolescent; D000328:Adult; D000368:Aged; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000188:drug therapy*; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy
D004365:Drugs, Chinese Herbal