[Laryngeal symptoms in patients with gastroesophageal reflux diseases].
Gastroesophageal reflux disease (GERD) is considered an important etiological factor of numerous larynx dysfunctions. The goal of our study was to describe larynx status of patients with GERD before and after treatment. Forty-five patients with GERD symptoms entered our study. GERD was confirmed in 24-hours pH-metric examination. Patients were treated with proton pump inhibitors in doses chosen accordingly to GERD severity. All patients underwent endoscopic evaluation of the larynx and acoustic voice analysis before and after the treatment. GERD was diagnosed in 35 out of 45 patients. Acoustic voice analysis revealed that voice disorders appeared more often in patients with severe than moderate or mild refluxes (p = 0.023). Laryngeal changes found in endoscopic evaluation also depended on reflux severity (p = 0.05). The voice quality improved (p = 0.031) and the changes in larynx diminished after anti-reflux treatment (p = 0.016).
Zalesska-Krecicka
Maria
M
Katedra i Klinika Otolaryngologii AM we Wrocławiu. krecicki@orl.am.wroc.pl
Waśko-Czopnik
Dorota
D
Krecicki
Tomasz
T
Paradowski
Leszek
L
Zatoński
Maciej
M
Horobiowska
Monika
M
D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007818:Laryngeal Diseases / Q000188:drug therapy* / Q000209:etiology*; D007828:Laryngoscopy; D008297:Male; D054328:Proton Pump Inhibitors; D017494:Proton Pumps / Q000627:therapeutic use; D012189:Retrospective Studies; D012720:Severity of Illness Index
D054328:Proton Pump Inhibitors; D017494:Proton Pumps