The histamine H(1)-receptor antagonist cetirizine does not interact with bradykinin B(1) or B(2)-receptors in vitro.
Christophe
B
B
UCB Pharma Sector, Respiratory Pharmacology Department, Chemin Du Foriest, 1420 Braine l'Alleud, Belgium. Bernard.Christophe@UCB-group.com
Maleux
M-R
MR
Gillard
M
M
Chatelain
P
P
Peck
M J
MJ
Massingham
R
R
D000818:Animals; D001920:Bradykinin / Q000494:pharmacology*; D017332:Cetirizine / Q000494:pharmacology*; D006168:Guinea Pigs; D039563:Histamine H1 Antagonists, Non-Sedating / Q000494:pharmacology; D007082:Ileum / Q000378:metabolism; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects*; D009197:Myenteric Plexus / Q000378:metabolism; D032389:Myocytes, Smooth Muscle / Q000378:metabolism; D011485:Protein Binding / Q000187:drug effects; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar; D018002:Receptors, Bradykinin / Q000378:metabolism*; D011969:Receptors, Histamine H1 / Q000378:metabolism*
D039563:Histamine H1 Antagonists, Non-Sedating; D018002:Receptors, Bradykinin; D011969:Receptors, Histamine H1; D001920:Bradykinin; D017332:Cetirizine