Hypercalcemia associated with a uterine leiomyoma: a case report and review of the literature.
BACKGROUND
Humoral hypercalcemia is known to be an important cause of hypercalcemia associated with malignancy. Humoral hypercalcemia due to benign conditions has been rarely reported.


METHODS
We report on a 45-year-old woman with humoral hypercalcemia secondary to uterine leiomyoma. Following the surgical removal of leiomyoma by hysterectomy, serum calcium, suppressed parathyroid hormone (PTH) and elevated parathyroid hormone-related protein (PTH-rP) levels were normalized.


CONCLUSIONS
To our knowledge, this is the second reported case of humoral hypercalcemia associated with uterine leiomyoma. We suggest that for women with hypercalcemia who had suppressed PTH and elevated PTH-rP levels, uterine leiomyoma should be included in the differential diagnosis.
Bilici
Ahmet
A
Department of Internal Medicine, Cerrahpasa School of Medicine, Istanbul, Turkey. ahmetknower@softhome.net
Doventas
Alper
A
Karadag
Berrin
B
Hekim
Nezih
N
Tezcan
Vecdet
V
D005260:Female; D006801:Humans; D006935:Hypercapnia / Q000097:blood / Q000209:etiology*; D007889:Leiomyoma / Q000097:blood*; D008875:Middle Aged; D014594:Uterine Neoplasms / Q000097:blood*