title: Image guided I125 prostate brachytherapy with Hybrid Interactive Mick technique in the community setting: How does it compare?
abstract: The aim of this study is to evaluate the target coverage, procedural techniques, and merits of Hybrid Interactive Mick (HIM) I125 transperineal permanent implantation (TPPI) of the prostate performed with 10 urologists in a community hospital. Detailed day 0 post-implant dosimetric evaluations of TPPI procedures were performed on 333 consecutive monotherapy patients treated between September 2000 and November 2003 at a single institution. All patients underwent TPPI with HIM. Pelvic and CXR films were obtained for a manual seed count at day 0 and again > day 90 on 175 patients. The HIM-prostate brachytherapy performed in a community hospital provided median D(90), V100, and V150 values of 157Gy, 94%, and 42.3%, respectively. 18% of patients had seed migration to the lungs while 2% had seed migration to the bladder. Only 7 patients (4%) had 2 or more seeds migrate to the lungs. Procedure times average 38 minutes and number of needles used averaged 18. The post-implant urinary retention rate was 2.1% Use of HIM-prostate brachytherapy in the community setting with multiple urologists reproducibly maintained excellent and consistent dosimetric coverage. Procedure times and number of needles used were minimized, and with careful attention to image-guided technique, seed migration to bladder and lung was also minimized.
authors.affiliation: Departments of Radiation Oncology, Memorial Regional Cancer Center, Springfield, Illinois 62781-0001, USA. Shanahan.thomas@mhsil.com
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Shanahan
authors.forename: Paul W
authors.initials: PW
authors.lastname: Mueller
authors.forename: David A
authors.initials: DA
authors.lastname: Roszhart
authors.forename: William C
authors.initials: WC
authors.lastname: Severino
authors.forename: Amit D
authors.initials: AD
authors.lastname: Bhate
authors.forename: Parashar J
authors.initials: PJ
authors.lastname: Nanavati
authors.forename: James B
authors.initials: JB
authors.lastname: Madison
authors.forename: Eugene J
authors.initials: EJ
authors.lastname: Dixon
authors.forename: Loren B
authors.initials: LB
authors.lastname: Ost
authors.forename: Lorraine L
authors.initials: LL
authors.lastname: Strode
authors.forename: Naomi S
authors.initials: NS
authors.lastname: Wands
authors.forename: Randy B
authors.initials: RB
authors.lastname: Maxey
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy / Q000295:instrumentation / Q000379:methods*; D005548:Foreign-Body Migration / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008168:Lung / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009339:Needles; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D001743:Urinary Bladder / Q000503:physiopathology; D016055:Urinary Retention
chemical_list: D007457:Iodine Radioisotopes