Design of chiral ligands for asymmetric catalysis: from C2-symmetric P,P- and N,N-ligands to sterically and electronically nonsymmetrical P,N-ligands.
For a long time, C(2)-symmetric ligands have dominated in asymmetric catalysis. More recently, nonsymmetrical modular P,N-ligands have been introduced. These ligands have been applied successfully in various metal-catalyzed reactions and, in many cases, have outperformed P,P- or N,N-ligands.
Pfaltz
Andreas
A
Department of Chemistry, University of Basel, St. Johanns-Ring 19, CH-4056 Basel, Switzerland. andreas.pfaltz@unibas.ch
Drury
William J
WJ