A database for management of gene expression data in situ.
BACKGROUND
To create a spatiotemporal atlas of Drosophila segmentation gene expression at cellular resolution.


RESULTS
The expression of segmentation genes plays a crucial role in the establishment of the Drosophila body plan. Using the IBM DB2 Relational Database Management System we have designed and implemented the FlyEx database. FlyEx contains 2832 images of 14 segmentation gene expression patterns obtained from 954 embryos and 2,073,662 quantitative data records. The averaged data is available for most of segmentation genes at eight time points. FlyEx supports operations on images of gene expression patterns. The database can be used to examine the quality of data, analyze the dynamics of formation of segmentation gene expression domains, as well as estimate the variability of gene expression patterns. We also provide the capability to download data of interest.


BACKGROUND
http://urchin.spbcas.ru/flyex, http://flyex.ams.sunysb.edu/flyex
Poustelnikova
Ekaterina
E
St. Petersburg State Polytechnic University, 29, Polytehnicheskaya ul., St Petersburg, 195251, Russia.
Pisarev
Andrei
A
Blagov
Maxim
M
Samsonova
Maria
M
Reinitz
John
J
D000818:Animals; D019521:Body Patterning / Q000502:physiology; D003628:Database Management Systems; D030541:Databases, Genetic; D004330:Drosophila / Q000196:embryology* / Q000502:physiology*; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism*; D020869:Gene Expression Profiling / Q000379:methods*; D018507:Gene Expression Regulation, Developmental / Q000502:physiology; D016247:Information Storage and Retrieval / Q000379:methods; D020407:Internet; D009024:Morphogenesis / Q000502:physiology; D014018:Tissue Distribution; D014584:User-Computer Interface
D029721:Drosophila Proteins