Immune responses to Puumala virus infection and the pathogenesis of nephropathia epidemica.
Puumala virus, causative agent of a mild form of hemorrhagic fever with renal syndrome, also known as nephropathia epidemica, induces long-lasting humoral and cellular immunity in patients. The virus itself is not cytopathic, and the immune responses to the virus may be involved in teh pathogenesis of the disease.
Terajima
Masanori
M
Center for Infectious Disease and Vaccine Research, S5-326 University of Massachusetts Medical School, Worcester, 01655, USA.
Vapalahti
Olli
O
Van Epps
Heather L
HL
Vaheri
Antti
A
Ennis
Francis A
FA
D018778:Hantavirus Infections / Q000453:epidemiology / Q000276:immunology; D006480:Hemorrhagic Fever with Renal Syndrome / Q000276:immunology* / Q000473:pathology / Q000503:physiopathology / Q000821:virology; D006801:Humans; D029262:Puumala virus