title: Reversed-phase liquid chromatographic enantioseparation by cycloalkylcarboxylates of cellulose and amylose.
abstract: Three novel cycloalkylcarboxylates, cyclopentyl, cyclohexyl, and 1-adamantylcarboxylates of cellulose and amylose were prepared and their chiral recognition abilities as chiral stationary phases (CSPs) for high-performance liquid chromatography (HPLC) were evaluated using a methanol-water mobile phase. Among these esters, cellulose tris(cyclohexylcarboxylate) showed a relatively high chiral recognition ability. The 1-adamantylcarboxylates of cellulose and amylose showed dissimilar chiral recognition abilities from the other two, probably due to the low degree of substitution and the high hydrophobicity of this group.
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Nagoya, Japan.
authors.forename: Takateru
authors.initials: T
authors.lastname: Kubota
authors.forename: Chiyo
authors.initials: C
authors.lastname: Yamamoto
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Okamoto
mesh_terms: D000688:Amylose / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002482:Cellulose / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D002853:Chromatography, Liquid / Q000379:methods*; D002942:Circular Dichroism; D009682:Magnetic Resonance Spectroscopy; D000432:Methanol / Q000737:chemistry; D008956:Models, Chemical; D011134:Polysaccharides / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D011134:Polysaccharides; D014867:Water; D002244:Carbon; D002482:Cellulose; D000688:Amylose; D000432:Methanol