[Hypokalemic paralysis with thyrotoxicosis].
Hypokalemic periodic paralysis as a complication of thyrotoxicosis (thyrotoxic periodic paralysis) most often occurs in east Asian men. It is characterised by recurrent episodes of flaccid paralysis, hypokalemia, and underlying hyperthyroidism. It needs to be distinguished from sporadic and familial forms of periodic hypokalemic paralysis. No disturbances in the acid-base state and no extracorporal potassium loss are present. We report on the typical case of a young Chinese man presenting with hypokalemic periodic paralysis associated with yet unknown Graves' disease. Intravenous substitution of potassium and oral propranolol were administered. Complete remission was achieved after 10 hours. After medical therapy had normalised thyroid hormone levels, no further hypokalemic paralytic attacks occurred.
Brandenburg
V M
VM
Medizinische Klinik II, Universitätsklinikum Aachen, Aachen. Vincent.Brandenburg@post.rwth-aachen.de
Knackstedt
C
C
Gobbelé
R
R
Graf
J
J
Schröder
J
J
Westerhuis
R
R
Kosinski
C M
CM
D000433:1-Propanol; D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D007008:Hypokalemia / Q000145:classification / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology; D020514:Hypokalemic Periodic Paralysis / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D011188:Potassium / Q000627:therapeutic use; D013971:Thyrotoxicosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D016896:Treatment Outcome
D000433:1-Propanol; D011188:Potassium