title: SCANMS: adjusting for multiple comparisons in sliding window neutrality tests.
abstract: CONCLUSIONS
  A Perl utility called SCANMS was written that operates on parametric bootstrap data generated by Hudson's simulator MS. SCANMS simulates sliding window analysis of Tajima's D or Fu and Li's D(*) or F(*) over the replicates and generates the empirical joint distribution of window minima and maxima. This distribution may then be used to calculate achieved significance values or significance cutoffs that account for multiple comparisons in sliding window analysis of real data.
  
  
  BACKGROUND
  SCANMS is available free of charge under the terms of the Academic Free License 2.0 and may be downloaded from http://www.lcb.uu.se/~dave/SCANMS
authors.affiliation: Department of Cell and Molecular Biology, Biomedical Center, Uppsala University, Box 596, SE-751 24 Uppsala, Sweden.
authors.forename: David H
authors.initials: DH
authors.lastname: Ardell
mesh_terms: D000465:Algorithms; D020407:Internet; D009716:Numerical Analysis, Computer-Assisted; D016415:Sequence Alignment / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software