Bioactivation and resistance to mitomycin C.
Seow
Helen A
HA
Department of Pharmacology and Developmental Therapeutics Program, Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Penketh
Philip G
PG
Baumann
Raymond P
RP
Sartorelli
Alan C
AC
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000378:metabolism; D001711:Biotransformation; D019008:Drug Resistance, Neoplasm; D006801:Humans; D016685:Mitomycin / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism
D000903:Antibiotics, Antineoplastic; D001426:Bacterial Proteins; D016685:Mitomycin; D010088:Oxidoreductases; C088145:mcrA protein, Streptomyces lavendulae