title: Sleep-disordered breathing in patients with idiopathic cardiomyopathy.
abstract: BACKGROUND
  Sleep-disordered breathing may adversely affect heart function, and thereby contribute to the progression of heart failure. A study was undertaken in patients with idiopathic cardiomyopathy to document the characteristics of sleep-disordered breathing.
  
  
  RESULTS
  Thirty-five patients with a diagnosis of idiopathic cardiomyopathy, comprising 20 patients with dilated cardiomyopathy (DCM) and 15 patients with hypertrophic cardiomyopathy (HCM), underwent overnight polysomnography. Of these 35, 16 (80%) of the DCM patients and 7 (47%) of the HCM patients had sleep-disordered breathing. Central sleep apnea-hypopnea syndrome (CSAHS) was seen in 10 DCM patients, but not in the HCM patients, and obstructive sleep apnea-hypopnea syndrome (OSAHS) was seen in 6 DCM patients and 7 HCM patients. CSAHS was seen in DCM patients with a low left ventricular ejection fraction. HCM patients with OSAHS had a significantly greater body mass index (BMI) than those without OSAHS and CSAHS (27.6 +/- 3.8 vs 22.0 +/- 4.0 kg/m2, p<0.05). DCM patients with OSAHS had a larger BMI than those with CSAHS (29.3 +/- 5.8 vs 24.2 +/- 4.0 kg/m2, p<0.05) and those without OSAHS and CSAHS (29.3 +/- 5.8 vs 21.3 +/- 3.1 kg/m2, p<0.05).
  
  
  CONCLUSIONS
  Sleep-disordered breathing is common in patients with idiopathic cardiomyopathy; half of DCM patients had CSAHS, which was closely associated with obesity.
authors.affiliation: Sleep Disorders Center and Department of Cardiology, Aichi Medical University School of Medicine, Japan. katsu-aic@umin.ac.jp
authors.forename: Katsuhisa
authors.initials: K
authors.lastname: Banno
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Shiomi
authors.forename: Ryujiro
authors.initials: R
authors.lastname: Sasanabe
authors.forename: Kazuo
authors.initials: K
authors.lastname: Otake
authors.forename: Rika
authors.initials: R
authors.lastname: Hasegawa
authors.forename: Masato
authors.initials: M
authors.lastname: Maekawa
authors.forename: Takayuki
authors.initials: T
authors.lastname: Ito
mesh_terms: D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000453:epidemiology*; D002312:Cardiomyopathy, Hypertrophic / Q000453:epidemiology*; D015897:Comorbidity; D045422:Continuous Positive Airway Pressure; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology; D017286:Polysomnography; D012891:Sleep Apnea Syndromes / Q000453:epidemiology* / Q000628:therapy; D020182:Sleep Apnea, Central / Q000453:epidemiology / Q000628:therapy; D020181:Sleep Apnea, Obstructive / Q000453:epidemiology / Q000628:therapy; D013577:Syndrome