title: Occupational exposures and non-Hodgkin's lymphoma in Southern Sweden.
abstract: In a case-control study based on 859 consecutive non-Hodgkin's lymphoma (NHL) cases identified through a tumor registry between 1990 and 1998, the authors collected demographic, occupational, exposure, and education information. Exposures were identified through self-report, reported occupational history, and the use of a job-exposure matrix. Conditional logistic regression analyses of the 859 cases and 1,310 controls showed increased risks in workers exposed to gasoline (odds ratio [OR] 1.46; 95% confidence interval [CI] 1.04, 2.05), aliphatic or alicyclic hydrocarbons (OR 1.75; CI 1.03, 2.99), aromatic hydrocarbons (OR 1.45; (CI 1.13, 1.86), and solvents for mole than five years (OR 1.59: CI 1.11, 2.28), as well as automobile mechanics (OR 1.82; CI 1.18, 2.81) and painters (OR 1.77; CI 1.13, 2.76). Exposures to pesticides and farming were not associated with increased risk. Prior radiotherapy was associated with increased risk (OR 2.84; (CI 1.85, 4.37). Concordance between analyses based on self-reported exposures, occupations, and the job-exposure matrix supported the links between organic solvents and prior radiotherapy and NHL but did not support associations between farming or pesticides and NHL.
authors.affiliation: Jubileum Institute, Department of Oncology, Lund University Hospital, Lund, Sweden. e_dryver@hotmail.com
authors.forename: Eric
authors.initials: E
authors.lastname: Dryver
authors.forename: Lars
authors.initials: L
authors.lastname: Brandt
authors.forename: Timo
authors.initials: T
authors.lastname: Kauppinen
authors.forename: Håkan
authors.initials: H
authors.lastname: Olsson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000395:Air Pollutants, Occupational / Q000633:toxicity; D002274:Carcinogens, Environmental / Q000633:toxicity; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006838:Hydrocarbons / Q000633:toxicity; D008228:Lymphoma, Non-Hodgkin / Q000139:chemically induced / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D010575:Pesticides / Q000633:toxicity; D011878:Radiotherapy / Q000009:adverse effects; D012997:Solvents / Q000633:toxicity; D013548:Sweden / Q000453:epidemiology
chemical_list: D000395:Air Pollutants, Occupational; D002274:Carcinogens, Environmental; D006838:Hydrocarbons; D010575:Pesticides; D012997:Solvents