Dual toxin-producing strain of Clostridium botulinum type Bf isolated from a California patient with infant botulism.
A retrospective study of Clostridium botulinum strains isolated from patients from California with infant botulism identified the fourth known C. botulinum strain that produces both type B and type F botulinum toxins. This unique strain represented 0.12% of the California infant botulism case isolates from 1976 to 2003. The relative concentrations of type B and F toxins produced were temperature dependent.
Barash
Jason R
JR
Infant Botulism Treatment and Prevention Program, California Department of Health Services, Richmond, California 94804, USA.
Arnon
Stephen S
SS
D000818:Animals; D001905:Botulinum Toxins / Q000096:biosynthesis*; D019274:Botulinum Toxins, Type A; D001906:Botulism / Q000382:microbiology*; D003014:Clostridium botulinum / Q000145:classification* / Q000302:isolation & purification* / Q000378:metabolism; D006801:Humans; D007223:Infant; D007928:Lethal Dose 50; D051379:Mice; D013696:Temperature
C096323:rimabotulinumtoxinB; D001905:Botulinum Toxins; D019274:Botulinum Toxins, Type A; C096321:botulinum toxin type F