[Fetal pseudohypoaldosteronism: a rare cause of hydramnios].
PHA is a rare cause of hydramnios, characterized by increased amniotic fluid levels of aldosterone and sodium. Two distinct genetic entities (PHA type I and PHA type II) are included. Both are stemmed by a target organ defect with diminished renal tubular responsiveness to aldosterone. The AA present a case in which pregnancy resulted in a preterm infant with severe hydramnios, metabolic acidosis, hyponatriemia, hyperkaliemia. Salt and fluid replacement significantly improved clinical and metabolic condition. However a growth deficiency (-2 SDS) persists at follow-up.
Liotta
A
A
Dipartimento Materno-Infantile, Università di Palermo.
Maggio
M C
MC
Iachininoto
R
R
Bellipanni
P F
PF
Calì
G
G
Arena
V
V
Arena
E
E
D005260:Female; D005315:Fetal Diseases; D006801:Humans; D007231:Infant, Newborn; D006831:Polyhydramnios / Q000209:etiology*; D011247:Pregnancy; D011546:Pseudohypoaldosteronism