title: Pollution correlated modifications of liver antioxidant systems and histopathology of fish (Cyprinidae) living in Seyhan Dam Lake, Turkey.
abstract: Specimen of freshwater fish (Cyprinidae) was collected from polluted and clean areas in dam Lake of Seyhan. Ten (n=10) fish were taken from each site. Liver preparations of fish from the two sources were comparatively assayed for glutathione-S-transferase (GST), lactic dehydrogenase (LDH), catalase (CAT), glucose-6-phosphate dehydrogenase (G6PDH), superoxide dismutase (SOD) and malondialdehyde (MDA). All systems were significantly (p<0.1) affected at the polluted site. The microscopic examination of the liver tissues of the fish living in the polluted area showed mononuclear inflammatory cell infiltration, cloudy degenerations, congestions and also micro- and macrovesicular fatty degenerations. These results provide evidence that both biochemical parameters and histopathological observations can be assumed as sensitive indicators of fish liver metabolism for polluted areas.
authors.affiliation: Arts and Sciences Faculty, University of Cukurova, Adana, Turkey. csg@cu.edu.tr
authors.forename: Sermin
authors.initials: S
authors.lastname: Gül
authors.forename: Ergül
authors.initials: E
authors.lastname: Belge-Kurutaş
authors.forename: Emel
authors.initials: E
authors.lastname: Yildiz
authors.forename: Aysel
authors.initials: A
authors.lastname: Sahan
authors.forename: Figen
authors.initials: F
authors.lastname: Doran
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D003530:Cyprinidae / Q000502:physiology*; D004781:Environmental Exposure; D007249:Inflammation; D008099:Liver / Q000201:enzymology*; D018384:Oxidative Stress; D014421:Turkey; D014873:Water Pollutants / Q000506:poisoning*
chemical_list: D000975:Antioxidants; D014873:Water Pollutants