title: A comparative study of clinico-radiological spectrum of tuberculosis among HIV seropositive and HIV seronegative patients.
abstract: BACKGROUND
  A study to determine the prevalence of human immunodeficiency virus (HIV) infection among tuberculosis patients and to compare the clinico-radiological spectrum of tuberculosis among HIV seropositive and seronegative patients was carried out in the Department of TB and Chest Diseases, CSM Medical University, Lucknow (Uttar Pradesh), India.
  
  
  METHODS
  A total of 1105 radiologically and/or bacteriologically confirmed patients of tuberculosis were screened for HIV infection during the years 1995 to 1997 and from 2000-2001.
  
  
  RESULTS
  Out of a total 1105 patients screened, 31(2.8%) were found to be HIV seropositive. Tuberculin positivity was less among HIV seropositive patients as compared to HIV seronegative patients (22.6% vs 76.4%; p < 0.001). There was no statistically significant difference in sputum smear positivity for acid-fast bacilli (AFB) among HIV seropositive and seronegative patients. Among HIV seropositive patients, mid and lower zone involvement, exudative lesions and mediastinal lymphadenopathy was more common as compared to the seronegative patients.
  
  
  CONCLUSIONS
  HIV seropositivity rates among tuberculosis patients was 2.8 percent. The presentation of tuberculosis was more often atypical among these patients.
authors.affiliation: Department of TB Diseases, K.G. Medical University, CSM Medical University, Lucknow, India. drprasad1@sancharnet.in
authors.forename: R
authors.initials: R
authors.lastname: Prasad
authors.forename: J K
authors.initials: JK
authors.lastname: Saini
authors.forename: R
authors.initials: R
authors.lastname: Gupta
authors.forename: R K
authors.initials: RK
authors.lastname: Kannaujia
authors.forename: S
authors.initials: S
authors.lastname: Sarin
authors.lastname: Suryakant
authors.forename: R
authors.initials: R
authors.lastname: Kulshreshth
authors.forename: V L
authors.initials: VL
authors.lastname: Nag
authors.forename: A K
authors.initials: AK
authors.lastname: Tripathi
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D018023:HIV Seronegativity; D006679:HIV Seropositivity / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D014376:Tuberculosis / Q000000981:diagnostic imaging* / Q000821:virology*