Paroxysmal kinesigenic dyskinesia manifestation of hyperthyroidism.
Sporadic paroxysmal kinesigenic dyskinesia (PKD) secondary to thyrotoxicosis is an extremely rare entity. A 36-year-old female presented with the features of PKD. Her investigations revealed thyrotoxicosis. Her dyskinesia did not respond to carbamazepine but remitted with the anti-thyroid drug, neomercazole. Perhaps hyperthyroidism-related PKD is a result of a metabolic disturbance of the basal ganglia circuits rather than a permanent and irreversible change.
Puri
V
V
Department of Neurology, G. B. Pant Hospital, New Delhi-110 002, India. vpuri@bol.net.in
Chaudhry
N
N
D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D013956:Antithyroid Agents / Q000627:therapeutic use; D001479:Basal Ganglia / Q000503:physiopathology; D002220:Carbamazepine / Q000627:therapeutic use; D002231:Carbimazole / Q000627:therapeutic use; D002819:Chorea / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology
D000927:Anticonvulsants; D013956:Antithyroid Agents; D002220:Carbamazepine; D002231:Carbimazole