[Assessment of structure and cardiac function of the left ventricle in young men with family history of hypertension].
Hypertension belongs to the group of most frequent illnesses of the circulatory system; especially due to its spread and great effects. It is determined as one of the most important medical, social and economical problems. The purpose of these studies was to find answers to questions, if young men between the ages of 18-30 with family medical hypertension history have a difference in middle systolic, diastolic and mean blood pressure in comparison to an analogical group without familiar hypertension. The influence of blood pressure on central circulatory system, such as the heart was also evaluated--measurements of left atrium and ventricular thickness and LV mass were made. Analysis was made of velocities through left atrioventricular ostium and aortic ostium system searching for early indexes of systolic and diastolic left ventricular dysfunction. 24-hour blood pressure registration was made by means of ERKA machine with frequency three times a hour during daily activity (6 a.m.-10 p.m.) and one time a hour during the night (10 p.m.-6 a.m.), arranging in this way 57 time points (measuring points). From the midst of evaluated parameters, morphology of the left heart the major difference was caused in the thickness of left ventricular posterior wall (p < 0.03) and in the mass counted after Penn convention (p < 0.02) and mass index (p < 0.05) of the left ventricular heart. There was no differences in reality in systolic and diastolic functions of the left ventricular heart. Parameters of the systolic function (ejection fraction, fractional shortening, mean rate of circumferential shortening of left ventricle, aortal integration flow) were minimally better in the group with familiar hypertension medical history, and parameters of diastolic function (mitral flow--analysis of its ingredients) in the group without family hypertension medical history. A significant linear regression was obtained between: mean systolic pressure from daily activity, 24-hour mean systolic pressure of left ventricular mass in both groups but significantly was higher in the group with family hypertension.
Balwierz
Paweł
P
Klinika Chorób Wewnetrznych i Diabetologii, Slaskiej Akademii Medycznej, Zabrze.
Grzeszczak
Władysław
W
D000328:Adult; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory; D016022:Case-Control Studies; D003971:Diastole; D015716:Electrocardiography, Ambulatory; D020022:Genetic Predisposition to Disease; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000235:genetics* / Q000503:physiopathology*; D016014:Linear Models; D008297:Male; D011044:Poland; D012307:Risk Factors; D013599:Systole; D013997:Time Factors; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000235:genetics* / Q000503:physiopathology*