title: Amidations using N,N '-carbonyldiimidazole: remarkable rate enhancement by carbon dioxide.
abstract: Carbon dioxide catalyzes the reaction of imidazolides with amines to form amides. A substantial rate enhancement is observed in the presence of CO(2) compared to the CO(2)-free case. The scope and limitations of this reaction are discussed.
authors.affiliation: Chemical Research and Development, Pfizer Inc., 0200-91-201, 7000 Portage Road, Kalamazoo, Michigan 49001, USA. rajappa.vaidyanathan@pfizer.com
authors.forename: Rajappa
authors.initials: R
authors.lastname: Vaidyanathan
authors.forename: Vikram G
authors.initials: VG
authors.lastname: Kalthod
authors.forename: Duc P
authors.initials: DP
authors.lastname: Ngo
authors.forename: Jerad M
authors.initials: JM
authors.lastname: Manley
authors.forename: Sean P
authors.initials: SP
authors.lastname: Lapekas