title: Pappenheimer bodies: a brief historical review.
abstract: Pappenheimer is credited with describing the intraerythrocytic collections of iron, or siderotic granules, as they appear on Wright-stained blood smears of certain patients after splenectomy. The history of their description and elucidation of their origin and disposition shows the interaction of morphology with the increasing understanding of red cell physiology in the mid-twentieth century.
authors.affiliation: Department of Medicine, Baylor College of Medicine and the Ben Taub General Hospital, Houston, Texas 77030, USA. dsears@bcm.tmc.edu
authors.forename: David A
authors.initials: DA
authors.lastname: Sears
authors.forename: Mark M
authors.initials: MM
authors.lastname: Udden
mesh_terms: D000756:Anemia, Sideroblastic / Q000097:blood; D003594:Cytoplasmic Granules; D004912:Erythrocytes / Q000502:physiology / Q000648:ultrastructure*; D006405:Hematology / Q000266:history*; D049673:History, 20th Century; D006801:Humans