title: Florid ischemic cholangitis due to leucocytoclastic vasculitis.
abstract: Ischemia-induced biliary tract lesions, called ischemic cholangitis, often lead to strictures of biliary ducts and cholestasis. Causes of ischemic changes of the biliary tract can be found in the arterial blood supply or in the peribiliary capillary plexus. Known examples are thrombosis after transplantation, intraoperative ligation, or the application of chemotherapeutic drugs. Rarely, such changes are due to inflammation of the blood vessels, such as occurs in polyarteritis nodosa or giant cell arteritis. We present a report of a 49-year old man with leucocytoclastic vasculitis after viral infection, influenza vaccination, and antibiotic treatment, leading to florid ischemic cholangitis. We conclude that hypersensitivity vasculitis must be included in the differential diagnosis of cholestasis and cholangitis.
authors.affiliation: Department of Pathology, University of Cologne, Joseph-Stelzmann-Str. 9, D-50931, Cologne, Germany.
authors.forename: Hans-Udo
authors.initials: HU
authors.lastname: Kasper
authors.forename: Volker
authors.initials: V
authors.lastname: Dries
authors.forename: Uta
authors.initials: U
authors.lastname: Drebber
authors.forename: Dirk
authors.initials: D
authors.lastname: Stippel
authors.forename: Katharina
authors.initials: K
authors.lastname: Reinhold
authors.forename: Hans Peter
authors.initials: HP
authors.lastname: Dienes
mesh_terms: D002761:Cholangitis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007511:Ischemia / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000150:complications* / Q000209:etiology