title: Clinicopathologic features of surgically resected primary gastric lymphoma.
abstract: OBJECTIVE
  To analyze the clinicopathologic characteristics of surgically resected gastric lymphoma patients.
  
  
  METHODS
  We retrospectively analyzed 57 surgically resected gastric lymphoma patients, dividing them into 2 subgroups: Low grade MALToma (the LG group), High grade MALToma and Diffuse large B cell lymphoma (the HG group).
  
  
  RESULTS
  The numbers of patients were: 20 in the LG group, 37 in the HG group. The diagnostic rate of gastroscopy was 34.8% at primary diagnosis and 50% including differential diagnoses. The positive rates of H pylori were similar between the 2 groups (68% vs 77%). Multiple lesions were found in 19.3%. The proportion of mucosal and submucosal lesions was 80.0%(16/20) in the LG group, and 24.3%(9/37) in the HG group (P<0.001). Lymph node invasion rates were 10.5%(2/19) in the LG group and 44.1%(15/34) in the HG group (P=0.031). The numbers of recurred patients were none in the LG group, and 8 in the HG group. By univariant analysis, group (P=0.024) and TNM stage (stage I, II vs stages III, IV, P=0.002) were found to be the significant risk factors. There was a tendency of higher recurrence rate in the subtotal gastrectomy group than in the total gastrectomy group (P=0.05).
  
  
  CONCLUSIONS
  The HG groups had a more advanced stage and a higher recurrence rate than the LG group. Although there was no difference between subtotal and total gastrectomies, more careful assessments of multiplicities and radical resections with lymph node dissections seem to be needed because of multiplicity and LN invasion even in LG group.
authors.affiliation: Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul, 110-744, Korea.
authors.forename: Seong-Ho
authors.initials: SH
authors.lastname: Kong
authors.forename: Min-A
authors.initials: MA
authors.lastname: Kim
authors.forename: Do-Joong
authors.initials: DJ
authors.lastname: Park
authors.forename: Hyuk-Joon
authors.initials: HJ
authors.lastname: Lee
authors.forename: Hye-Seung
authors.initials: HS
authors.lastname: Lee
authors.forename: Chul-Woo
authors.initials: CW
authors.lastname: Kim
authors.forename: Han-Kwang
authors.initials: HK
authors.lastname: Yang
authors.forename: Dae-Seog
authors.initials: DS
authors.lastname: Heo
authors.forename: Kuhn-Uk
authors.initials: KU
authors.lastname: Lee
authors.forename: Kuk-Jin
authors.initials: KJ
authors.lastname: Choe
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D000328:Adult; D000368:Aged; D018572:Disease-Free Survival; D005260:Female; D005743:Gastrectomy; D016481:Helicobacter Infections / Q000401:mortality / Q000473:pathology; D006801:Humans; D016393:Lymphoma, B-Cell / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D016403:Lymphoma, Large B-Cell, Diffuse / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome