title: Asymmetric catalysis using self-assembled chiral bidentate P,P-ligands.
abstract: A strategy is described for modular catalyst development based upon metal-directed self-assembly of bifunctional subunits around a structural metal to form a heteroleptic complex in which a second set of ligating groups are now suitably disposed to bind a second metal to form a catalytic site. A library of chiral diphosphites was prepared via metal-directed self-assembly and used in a simple asymmetric allylic amination, giving enantiomeric excesses as high as 97%.
authors.affiliation: Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588-0304, USA. jtakacs1@unl.edu
authors.forename: James M
authors.initials: JM
authors.lastname: Takacs
authors.forename: D Sahadeva
authors.initials: DS
authors.lastname: Reddy
authors.forename: Shin A
authors.initials: SA
authors.lastname: Moteki
authors.forename: Di
authors.initials: D
authors.lastname: Wu
authors.forename: Hector
authors.initials: H
authors.lastname: Palencia