[Hematological and histopathological evaluation of BALB/c and C57BL/6 mice exposed to Cytoplasmic Repetitive Antigen and Flagellar Repetitive Antigen recombinant antigens of Trypanosoma cruzi].
The Cytoplasmic Repetitive Antigen and Flagellar Repetitive Antigen recombinant antigens of Trypanosoma cruzi were inoculated into BALB/c and C57BL/6 mice and its effects evaluated at hematological and histopathological levels. The results showed that the histological pattern of the organs and the hematological profile of mice were not modified suggesting that these antigens are not harmful for the animal.
Pereira
Valéria Rêgo Alves
VR
Departamento de Imunologia do Centro de Pesquisas Aggeu Magalhães da Fundação Oswaldo Cruz, Recife, PE.
de Lorena
Virginia Maria Barros
VM
Galvão-da Silva
Ana Paula
AP
Nakazawa
Mineo
M
da Silva
Edimilson Domingos
ED
Ferreira
Antonio Gomes Pinto
AG
Montarroyos
Ulisses
U
Coutinho
Eridan de Medeiros
Ede M
Gomes
Yara de Miranda
Yde M
D000818:Animals; D000953:Antigens, Protozoan / Q000008:administration & dosage / Q000276:immunology*; D014355:Chagas Disease / Q000097:blood / Q000276:immunology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000276:immunology; D014349:Trypanosoma cruzi / Q000276:immunology*
D000953:Antigens, Protozoan; D011994:Recombinant Proteins