title: Therapeutic angiogenesis: the next frontier for interventional radiology.
abstract: The field of interventional radiology has traditionally relied on mechanical methods to treat vascular disease, such as angioplasty balloons and stents. Although there have been a number of important technical advances in endovascular devices, there are still a number of patients who are not candidates for percutaneous or surgical revascularization. As we approach the technical limits of these newer devices, therapeutic angiogenesis may play an ever-increasing role in the future. Interventional radiologists have unique delivery skills that would complement the on-going research in this area. It is the goal of this article to serve as a primer for interventional radiologists on the agents and techniques used in this exciting field.
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.
authors.forename: Robert P
authors.initials: RP
authors.lastname: Liddell
authors.forename: Clifford R
authors.initials: CR
authors.lastname: Weiss
authors.forename: Lawrence V
authors.initials: LV
authors.lastname: Hofmann
mesh_terms: D043925:Angiogenesis Inducing Agents / Q000008:administration & dosage*; D000818:Animals; D003097:Collateral Circulation; D004730:Endothelium, Vascular / Q000166:cytology / Q000502:physiology; D015316:Genetic Therapy; D006801:Humans; D018919:Neovascularization, Physiologic / Q000502:physiology; D015641:Radiography, Interventional; D033581:Stem Cell Transplantation
chemical_list: D043925:Angiogenesis Inducing Agents