title: Antibiotic production by a Roseobacter clade-affiliated species from the German Wadden Sea and its antagonistic effects on indigenous isolates.
abstract: A strain affiliated with the Roseobacter clade and producing a new antibiotic named tropodithietic acid (L. Liang, Ph.D. thesis, University of Göttingen, Göttingen, Germany, 2003) was isolated from the German Wadden Sea. The compound showed strong inhibiting properties with respect to marine bacteria of various taxa and marine algae. Antibiotic production was found to occur during the complete growth phase. Strain mutants without antagonistic properties appeared several times spontaneously.
authors.affiliation: Institute for Chemistry and Biology of the Marine Environment, University of Oldenburg, D-26111 Oldenburg, Germany. Thorsten.Brinkhoff@icbm.de
authors.forename: Thorsten
authors.initials: T
authors.lastname: Brinkhoff
authors.forename: Gabriela
authors.initials: G
authors.lastname: Bach
authors.forename: Thorsten
authors.initials: T
authors.lastname: Heidorn
authors.forename: Lanfang
authors.initials: L
authors.lastname: Liang
authors.forename: Andrea
authors.initials: A
authors.lastname: Schlingloff
authors.forename: Meinhard
authors.initials: M
authors.lastname: Simon
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D004269:DNA, Bacterial / Q000235:genetics; D056890:Eukaryota / Q000187:drug effects; D005858:Germany; D008969:Molecular Sequence Data; D010802:Phylogeny; D041904:Roseobacter / Q000145:classification / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D012623:Seawater / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial