Severe fetal cytomegalovirus infection associated with cerebellar hemorrhage.
Cytomegalovirus (CMV) is the most common cause of congenital infection worldwide. We report on a fatal fetal manifestation of primary maternal CMV infection including cerebellar hemorrhage and hydrops. The diagnosis was established by maternal serological tests, culture and polymerase chain reaction testing of amniotic fluid and fetal blood. The pregnancy was terminated. Postmortem examination confirmed the diagnosis.
Ortiz
J U
JU
Section of Perinatal Medicine, Department of Obstetrics and Gynecology, Technical University, Munich, Germany.
Ostermayer
E
E
Fischer
T
T
Kuschel
B
B
Rudelius
M
M
Schneider
K T M
KT
D000027:Abortion, Incomplete; D000328:Adult; D002526:Cerebellar Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000821:virology*; D002543:Cerebral Hemorrhage / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000821:virology*; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000000981:diagnostic imaging; D017809:Fatal Outcome; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000821:virology*; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis; D016216:Ultrasonography, Prenatal / Q000379:methods