title: Management of Bowen's disease of the skin.
abstract: Each year around 15 per 100,000 people in the UK develop intra-epidermal squamous cell carcinoma--Bowen's disease. The lesions of Bowen's disease are slow-growing, erythematous scaly skin plaques that cause few, if any, symptoms. However, if left untreated, they progress to invasive squamous cell carcinoma in 3-5% of patients. Here we review the management of Bowen's disease.
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D001913:Bowen's Disease / Q000628:therapy*; D003365:Costs and Cost Analysis; D017679:Cryotherapy / Q000379:methods; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D010778:Photochemotherapy / Q000379:methods; D012878:Skin Neoplasms / Q000628:therapy*
chemical_list: D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil