Artecoll granuloma: a rare adverse reaction induced by microimplant in the treatment of neck wrinkles.
BACKGROUND
Artecoll is now being widely used as an injectable aesthetic microimplant for the treatment of wrinkles because of its long-lasting cosmetic effects and the rarity of late complications, including foreign body granulomas. Recently, however, several cases of Artecoll-induced granulomas on the face have been reported, especially in patients receiving overly superficial or overly correcting implants.


RESULTS
A 50-year-old Korean woman who had been treated with Artecoll for the correction of the neck wrinkles presented 4 years later with an extensive Artecoll-induced foreign body granuloma along the injection sites in the neck. After three intralesional injections of triamcinolone acetonide, the lesions had almost disappeared.


CONCLUSIONS
To our knowledge, this case is the first report of an extensive Artecoll-induced granuloma on the neck. Our findings suggest that Artecoll not be used as implant material in thin and constantly movable skin, such as that of the neck.
Kim
Kyoung-Jin
KJ
Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Poongnap-dong, Songpa-gu, Seoul 138-736, Korea. kimkj20@dreamwiz.com
Lee
Hae-Woong
HW
Lee
Mi-Woo
MW
Choi
Jee-Ho
JH
Moon
Kee-Chan
KC
Koh
Jai-Kyoung
JK
D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D001672:Biocompatible Materials / Q000008:administration & dosage / Q000009:adverse effects*; D003094:Collagen / Q000008:administration & dosage / Q000009:adverse effects*; D003357:Cosmetic Techniques / Q000009:adverse effects; D005260:Female; D015745:Granuloma, Foreign-Body / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D015552:Injections, Intralesional; D007279:Injections, Subcutaneous; D008863:Microspheres; D008875:Middle Aged; D009333:Neck; D019904:Polymethyl Methacrylate / Q000008:administration & dosage / Q000009:adverse effects* / Q000031:analogs & derivatives*; D019736:Prostheses and Implants / Q000009:adverse effects*; D015595:Skin Aging; D016896:Treatment Outcome; D014221:Triamcinolone / Q000008:administration & dosage
D000893:Anti-Inflammatory Agents; C445359:Artecoll; D001672:Biocompatible Materials; D014221:Triamcinolone; D003094:Collagen; D019904:Polymethyl Methacrylate