Novel dual acting molecules possessing 5-lipoxygenase enzyme inhibition and histamine H(1) receptor antagonist properties.
Scannell
R T
RT
UCB Research, Inc., 840 Memorial Drive, Cambridge, MA 02139, USA. ralph.scannell@ucb-group.com
Arrington
M P
MP
Bayless
L
L
Cai
X
X
Eckman
J B
JB
Eckert
M
M
Ene
D G
DG
Ellis
J L
JL
Hussoin
S
S
Latham
G M
GM
Lewis
T A
TA
Libertine
L
L
Nicolas
J
J
Selig
W M
WM
Schwartz
C E
CE
Wels
B F
BF
Wypij
D M
DM
Young
M A
MA
Zou
D
D
D000818:Animals; D016466:CHO Cells; D006224:Cricetinae; D003412:Cricetulus; D006168:Guinea Pigs; D017442:Histamine Agonists / Q000494:pharmacology*; D006634:Histamine H1 Antagonists / Q000494:pharmacology*; D006636:Histamine Release / Q000187:drug effects; D006801:Humans; D007975:Leukotriene B4 / Q000032:analysis* / Q000097:blood; D016859:Lipoxygenase Inhibitors; D008297:Male; D011738:Pyrilamine / Q000494:pharmacology
D017442:Histamine Agonists; D006634:Histamine H1 Antagonists; D016859:Lipoxygenase Inhibitors; D007975:Leukotriene B4; D011738:Pyrilamine