title: An integrative and interactive framework for improving biomedical pattern discovery and visualization.
abstract: Recent progress in medical sciences has led to an explosive growth of data. Due to its inherent complexity and diversity, mining such volumes of data to extract relevant knowledge represents an enormous challenge and opportunity. Interactive pattern discovery and visualization systems for biomedical data mining have received relatively little attention. Emphasis has been traditionally placed on automation and supervised classification problems. Based on self-adaptive neural networks and pattern-validation statistical tools, this paper presents a user-friendly platform to support biomedical pattern discovery and visualization. It has been tested on several types of biomedical data, such as dermatology and cardiology data sets. The results indicate that in comparison to traditional techniques, such as Kohonen Maps, this platform may significantly improve the effectiveness and efficiency of pattern discovery and classification tasks, including problems described by several classes. Furthermore, this study shows how the combination of graphical and statistical tools may make these patterns more meaningful.
authors.affiliation: School of Computing and Mathematics, University of Ulster, Jordanstown, BT37 OQB, Northern Ireland, UK. hy.wang@ulster.ac.uk
authors.forename: Haiying
authors.initials: H
authors.lastname: Wang
authors.forename: Francisco
authors.initials: F
authors.lastname: Azuaje
authors.forename: Norman
authors.initials: N
authors.lastname: Black
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D003872:Dermatitis / Q000145:classification / Q000175:diagnosis*; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D003937:Diagnosis, Differential; D004569:Electroencephalography; D006801:Humans; D008954:Models, Biological; D016571:Neural Networks, Computer; D010363:Pattern Recognition, Automated; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012891:Sleep Apnea Syndromes / Q000145:classification / Q000175:diagnosis*; D013223:Statistics as Topic; D018511:Systems Integration