title: Invitro drug sensitivity of Trichophyton species against griseofulvin and ketoconazole.
abstract: The in vitro activity of griseofulvin and ketoconazole was investigated against Trichophyton mentagrophytes (Robin) Blanchard and T. Simii (Pinoy) Stockdale, Mackenzie and Austwick. A gradual decrease in growth was observed with increase in concentration of both antibiotics. Ketoconazole was the more effective antibiotic than griseofulvin as it observed to inhibit > 50% mycelial weight even at a lower concentration of 100 ppm. While griseofulvin was effective to cause > 50% growth inhibition only at higher dosage of 400 ppm.
authors.affiliation: Department of Botany, St. John's College, Agra 282 002, India.
authors.forename: Sumita
authors.initials: S
authors.lastname: Dodia
authors.forename: Ritu
authors.initials: R
authors.lastname: Bajpai
authors.forename: B Geetha
authors.initials: BG
authors.lastname: Singh
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D003881:Dermatomycoses / Q000382:microbiology; D006118:Griseofulvin / Q000494:pharmacology*; D006801:Humans; D007654:Ketoconazole / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D014249:Trichophyton / Q000187:drug effects*
chemical_list: D000935:Antifungal Agents; D006118:Griseofulvin; D007654:Ketoconazole