title: Assessment of chemotherapy-induced oral complications in children with cancer.
abstract: OBJECTIVE
  To assess children with cancer for oral complications using the oral assessment guide (OAG) and ascertain the efficacy of an oral hygiene care regimen in children undergoing chemotherapy and at 1 to 2 weeks postchemotherapy administration.
  
  
  METHODS
  Thirty pediatric cancer patients with either leukemia or lymphoma were randomly selected from 3 medical centers. A quasi-experimental design was used to evaluate the difference between pre- and post-oral hygiene care. Descriptive and inferential statistical techniques were used to analyze the data. The interrater agreement between the nurse and the dentist was calculated using a Kappa score. A paired t test was to examine the difference between pre- and post-oral hygiene care regimen.
  
  
  RESULTS
  The OAG scores ranged from 8 to 24. The higher the score, the more severe the oral complications. Ninety-six percent of the participants had a score > or = 9, on the pre-test, 26.7% had an OAG score > or = 12. Oral complications included ulcerated mucous membranes, dry lips, deeper or raspy voice, and oral debris. No scores were > or = 12 on the OAG following the posttest. The oral hygiene care regimen significantly improved oral assessment among patients (P < .05).
  
  
  CONCLUSIONS
  The authors postulate that the OAG and oral hygiene care regimen may be clinically useful in improving oral assessment and hygiene in children with cancer during and after chemotherapy, thus decreasing associated infection and enhancing patient comfort.
authors.affiliation: Department of Nursing, Tri-Service General Hospital, Taipei, Taiwan. chencf33@ms35.hinet.net
authors.forename: Chia-Feng
authors.initials: CF
authors.lastname: Chen
authors.forename: Ru-Hwa
authors.initials: RH
authors.lastname: Wang
authors.forename: Shin-Nan
authors.initials: SN
authors.lastname: Cheng
authors.forename: Yue-Cune
authors.initials: YC
authors.lastname: Chang
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007938:Leukemia / Q000188:drug therapy; D008223:Lymphoma / Q000188:drug therapy; D016294:Models, Nursing; D009061:Mouth Mucosa; D024802:Nurse's Role; D009730:Nursing Assessment / Q000379:methods* / Q000592:standards; D015403:Nursing Evaluation Research; D015588:Observer Variation; D009859:Oncology Nursing / Q000379:methods; D009910:Oral Hygiene / Q000379:methods / Q000451:nursing; D009911:Oral Hygiene Index; D010353:Patient Education as Topic; D010371:Pediatric Nursing / Q000379:methods; D013280:Stomatitis / Q000139:chemically induced / Q000517:prevention & control; D013624:Taiwan
chemical_list: D000970:Antineoplastic Agents