Relaxin kinetics during dynamic exercise in patients with chronic heart failure.
Background: We investigated circulating relaxin (RLX) and its potential role in human congestive heart failure (CHF) at rest and after physical exercise. Methods: A total of 10 healthy controls and 35 patients with stable CHF were enrolled in the study. Results: RLX plasma concentrations at rest and after exercise were comparable in patients with CHF and in controls. Conclusion: These findings suggest that RLX does not play a major role as a circulating hormone in human CHF.
Krüger
Stefan
S
Medical Clinic I and the Institute of Clinical Chemistry, University of Technology, Aachen, Germany.
Graf
Jürgen
J
Merx
Marc W.
MW
Stickel
Tina
T
Kunz
Dagmar
D
Hanrath
Peter
P
Janssens
Uwe
U