Palladium-catalyzed ring-opening reaction of methyleneaziridines with carboxylic acids: synthesis of alpha-amidoketones.
In the presence of palladium catalysts, the reaction of methyleneaziridines 1 with carboxylic acids 2proceeded smoothly to give the corresponding alpha-amidoketones 3 in good to high yields.
Oh
Byoung Ho
BH
Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan yoshi@yamamoto1.chem.tohoku.ac.jp
Nakamura
Itaru
I
Yamamoto
Yoshinori
Y