title: Membrane curvature: how BAR domains bend bilayers.
abstract: An important new structure suggests the BAR domain is a membrane-binding module that can both produce and sense membrane curvature. BAR resembles a banana that binds membranes electrostatically through its positively charged, concave surface.
authors.affiliation: Laboratory of Cellular and Molecular Biophysics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.
authors.forename: Joshua
authors.initials: J
authors.lastname: Zimmerberg
authors.forename: Stuart
authors.initials: S
authors.lastname: McLaughlin
mesh_terms: D020727:ADP-Ribosylation Factors / Q000378:metabolism; D000818:Animals; D055592:Biophysical Phenomena; D001703:Biophysics; D004330:Drosophila; D020690:GTPase-Activating Proteins / Q000378:metabolism; D008051:Lipid Bilayers / Q000378:metabolism*; D008081:Liposomes / Q000378:metabolism*; D009419:Nerve Tissue Proteins / Q000378:metabolism* / Q000502:physiology; D017434:Protein Structure, Tertiary / Q000502:physiology; D055672:Static Electricity
chemical_list: D020690:GTPase-Activating Proteins; D008051:Lipid Bilayers; D008081:Liposomes; D009419:Nerve Tissue Proteins; C075637:amphiphysin; D020727:ADP-Ribosylation Factors