[Churg-Strauss syndrome--cardiac problem in lung disease department].
Eosinophilia and pleural effusion may suggest pulmonary eosinophilia. We present a case of 42 years old woman with hypereosinophilia history since 5 months and no evidence of parasitic infections. She had no history of heart disease. Laboratory tests revealed eosinophilia (13.0 x 10(9)/l) and elevated serum IgE (2050 IU/ml), ANCA was not detected. ECP was not elevated. Pleural effusion contained 37% of eosinophils. An ECG revealed low voltage of QRS in all leads and Q waves in leads Vi-V-3. An echocardiography showed enlargement of left auricle and left ventricle with ejection fraction = 35%. The only pulmonary manifestation in this case was eosinophilic pleural effusions associated with congestive heart failure. A women was treated with prednisone 1 mg/kg/d and cyclophosphamide 2 mg/kg/d with clinical improvement and normalisation of eosinophil number in peripheral blood. But echocardiographic picture of the heart was nor better during 2 months of observation.
Załeska
Monika
M
III Kliniki Chorób Płuc, Instytutu Gruźlicy i Chorób Płuc w Warszawie.
Roszkowska-Sliz
Barbara
B
Wiatr
Elzbieta
E
Tomkowski
Witold
W
Bestry
Iwona
I
Roszkowski-Sliz
Kazimierz
K
D000328:Adult; D015267:Churg-Strauss Syndrome / Q000150:complications* / Q000503:physiopathology; D004452:Echocardiography; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000175:diagnosis; D006801:Humans; D010996:Pleural Effusion / Q000097:blood / Q000209:etiology*; D011657:Pulmonary Eosinophilia / Q000097:blood / Q000209:etiology*; D013997:Time Factors