Molecular characterization of the gene encoding a new AmpC beta-lactamase in a clinical strain of acinetobacter genomic species 3.
A presumptive chromosomal cephalosporinase (pI, 9.0) from a clinical strain of Acinetobacter genomic species 3 (AG3) is reported. The nucleotide sequence of this beta-lactamase shows for the first time the gene encoding an AmpC enzyme in AG3. In addition, the biochemical properties of the novel AG3 AmpC beta-lactamase are reported
Beceiro
Alejandro
A
Servicio de Microbiología. Complejo Hospitalario Universitario Juan Canalejo, 15006 La Coruña, Spain.
Dominguez
Lourdes
L
Ribera
Anna
A
Vila
Jordi
J
Molina
Francisca
F
Villanueva
Rosa
R
Eiros
Jose Maria
JM
Bou
German
G
D000150:Acinetobacter / Q000235:genetics*; D000595:Amino Acid Sequence; D001426:Bacterial Proteins; D001483:Base Sequence; D002876:Chromosomes, Bacterial / Q000235:genetics; D004269:DNA, Bacterial / Q000235:genetics; D005798:Genes, Bacterial / Q000235:genetics*; D007525:Isoelectric Focusing; D007700:Kinetics; D008969:Molecular Sequence Data; D001618:beta-Lactamases / Q000235:genetics* / Q000378:metabolism
D001426:Bacterial Proteins; D004269:DNA, Bacterial; C048795:AmpC beta-lactamases; D001618:beta-Lactamases