Detection of inducible clindamycin resistance of staphylococci in conjunction with performance of automated broth susceptibility testing.
This study has shown that inducible clindamycin resistance in staphylococci can be detected by disk testing on sheep blood agar inoculum purity plates used with the bioMerieux VITEK 2. Tests of 150 erythromycin-resistant isolates correlated with standard D-zone tests on Mueller-Hinton agar and with PCR for erm(A), erm(C), and msr(A).
Jorgensen
J H
JH
Department of Pathology, University of Texas Health Science Center, San Antonio, Texas 78229, USA. jorgensen@uthscsa.edu
Crawford
S A
SA
McElmeel
M L
ML
Fiebelkorn
K R
KR
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D002981:Clindamycin / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004917:Erythromycin / Q000494:pharmacology; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D016133:Polymerase Chain Reaction; D013210:Staphylococcus / Q000187:drug effects* / Q000235:genetics
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D002981:Clindamycin; D004917:Erythromycin