title: Effect of fatty acids on the membrane potential of an alkaliphilic bacillus.
abstract: Effect of various fatty acids on the membrane potential of an alkaliphilic Bacillus, YN-2000, was examined. Addition of unsaturated fatty acids such as palmitoleic acid, oleic acid, linoleic acid, and linolenic acid at 30 microM caused the instantaneous depolarization of the membrane potential of the bacterium, which appears to result in the drastic decrease of viability. On the other hand, no depolarization was detected by the addition of saturated acids such as palmitic acid, stearic acid, and 12-hydroxystearic acid even at 1 mM.
authors.affiliation: Department of Chemistry, Faculty of Science, Chiba University, Yayoi, Chiba 263-8522, Japan.
authors.forename: Hisami
authors.initials: H
authors.lastname: Furusawa
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Koyama
mesh_terms: D001407:Bacillus / Q000737:chemistry / Q000187:drug effects / Q000254:growth & development / Q000502:physiology*; D002462:Cell Membrane / Q000502:physiology; D005227:Fatty Acids / Q000494:pharmacology*; D005229:Fatty Acids, Monounsaturated / Q000494:pharmacology; D005453:Fluorescence; D019787:Linoleic Acid / Q000494:pharmacology; D008564:Membrane Potentials / Q000187:drug effects*; D019301:Oleic Acid / Q000494:pharmacology; D019308:Palmitic Acid / Q000494:pharmacology; D012235:Rhodamines; D013229:Stearic Acids / Q000494:pharmacology
chemical_list: D005227:Fatty Acids; D005229:Fatty Acids, Monounsaturated; D012235:Rhodamines; D013229:Stearic Acids; C026188:rhodamine 6G; C008757:palmitoleic acid; D019301:Oleic Acid; D019308:Palmitic Acid; C031183:stearic acid; D019787:Linoleic Acid