[Psychiatric and central nervous system involvement in Sjogren's syndrome].
OBJECTIVE
To study psychiatric features and the manifestations of central nervous system involvement in Chinese patients with primary Sjogren's syndrome (PSS).


METHODS
The Minnesota Multiphasic Personality Inventory (MMPI) was used to study 27 PSS female patients and 57 healthy women. The results from two groups were compared. Ten SS patients were evaluated by electroencephalography (EEG), transcranial doppler ultrasound (TCD) and magnetic resonance imaging (MRI).


RESULTS
Of 27 patients tested, the three highest clinical mean scales included Hypochondriasis (Hs), Hysteria (Hy), Psychasthenia (Pt) were found. When PSS group was compared with normal control, T scores of SS patients were significantly higher than the healthy women in Hs, Hy. Abnormal EEG was found in 3 of 9 PSS patients. TCD was abnormal in 5 of 9 patients. MRI in 1 patient showed abnormality.


CONCLUSIONS
This study shows that the personality of PSS patients is abnormal, the features are neuroticism. Central nervous system was markedly involved in Chinese patients with PSS, including abnormal EEG and TCD. The changes of central nervous system may be related to abnormalities of psychiatric changes.
Wang
Yan
Y
Salivary Gland Disease Center, Beijing Hospital for Stomatology, Capital University of Medical Sciences, Beijing 100050, China.
Wang
Song-ling
SL
Zou
Yi-zhuang
YZ
Luan
Guo-ming
GM
D000328:Adult; D000368:Aged; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008950:MMPI; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000523:psychology*; D017585:Ultrasonography, Doppler, Transcranial