Characterization of an anonymous molecular marker strongly linked to Escherichia coli strains causing neonatal meningitis.
An anonymous 14.9-kb rrn-containing HindIII fragment is strongly linked to Escherichia coli strains causing neonatal meningitis. We show in this report that this fragment does not encode new virulence factors but lacks arpA, a gene common in avirulent E. coli strains, and we developed a PCR test to detect this fragment.
Clermont
Olivier
O
Laboratoire d'Etudes de Génétique Bactérienne dans les Infections de l'Enfant (EA3105), Université Denis Diderot-Paris 7, France.
Bonacorsi
Stéphane
S
Bingen
Edouard
E
D015247:Deoxyribonuclease HindIII / Q000378:metabolism*; D004926:Escherichia coli / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000382:microbiology; D029968:Escherichia coli Proteins / Q000235:genetics; D017353:Gene Deletion; D005819:Genetic Markers; D006801:Humans; D007231:Infant, Newborn; D020814:Meningitis, Escherichia coli / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D012407:rRNA Operon / Q000235:genetics*
D029968:Escherichia coli Proteins; D005819:Genetic Markers; D015247:Deoxyribonuclease HindIII