title: Massive chloroquine intoxication: importance of early treatment and pre-hospital treatment.
abstract: Chloroquine intoxication, despite therapeutic improvements, remains a potentially serious condition. We report a case of a 25-year-old patient, having ingested 10 g of chloroquine, a dose commonly considered to be lethal. Thanks to appropriate early medical treatment, this patient's outcome was favourable. To our knowledge, the literature contains no other report of survival of a patient after such an intake. This report emphasises the need to use a pre-designed medical care protocol to implement appropriate therapy as rapidly as possible.
authors.affiliation: Département d'Anesthésie Réanimation, SAMU 21-Hôpital Général, Rue Faubourg Raines, 21000 Dijon, France. irene.mesant@chu-dijon.fr
authors.forename: Irène
authors.initials: I
authors.lastname: Messant
authors.forename: Nicolas
authors.initials: N
authors.lastname: Jérémie
authors.forename: François
authors.initials: F
authors.lastname: Lenfant
authors.forename: Marc
authors.initials: M
authors.lastname: Freysz
mesh_terms: D000328:Adult; D002738:Chloroquine / Q000506:poisoning*; D004837:Epinephrine / Q000008:administration & dosage; D005260:Female; D005751:Gastric Lavage; D006801:Humans; D011041:Poisoning / Q000628:therapy; D013406:Suicide, Attempted; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D002738:Chloroquine; D004837:Epinephrine