Composite metastatic carcinoma in lymph nodes of patients with concurrent medullary and papillary thyroid carcinoma: a report of two cases.
Synchronous occurrence of medullary and papillary carcinoma of the thyroid gland is very rare. We describe two cases of synchronous medullary and papillary carcinoma of the thyroid. In both cases, medullary carcinoma and papillary carcinoma were separate in the thyroid but mixed in some of the lymph node metastases. A review of the literature and our own cases revealed that composite medullary and papillary carcinoma metastases in the lymph nodes is a common feature of patients with synchronous medullary and papillary carcinoma of the thyroid gland.
Seki
Tomohisa
T
Keio University School of Medicine, Tokyo, Japan.
Kameyama
Kaori
K
Hayashi
Hiroshi
H
Nagahama
Mitsuji
M
Masudo
Katsuhiko
K
Fukunari
Nobuhiro
N
Tanaka
Kumi
K
Sugino
Kiminori
K
Ito
Koichi
K
Takami
Hiroshi
H
D000328:Adult; D000368:Aged; D018276:Carcinoma, Medullary / Q000378:metabolism / Q000473:pathology*; D002291:Carcinoma, Papillary / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis / Q000473:pathology*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000378:metabolism / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000378:metabolism / Q000473:pathology*