[Clinical observation on effect of jingling oral liquid in treating infertile patients with varicocele after varicocelectomy].
OBJECTIVE
To observe the clinical effect of Jingling oral liquid (JLOL) in treating infertile patients with varicocele after varicocelectomy.


METHODS
Sixty patients were randomly divided into two groups, the 30 patients in the treated group treated by JLOL, and the 30 in the control group treated with intramuscular injection of human chorionic gonadotropine (hCG).


RESULTS
The pregnant rate of patient's wife in the treated group was 76.6%, while that in the control group was 40.0%, showing significant difference between them (P < 0.05). The quality of semen was improved in both groups (P < 0.05 or P < 0.01), and the improvement was better in the treated group than that in the control group (P < 0.05). The reproductive hormones were also improved in both groups (P < 0.01). In the treated group, levels of superoxide dismutase (SOD) and zinc in semen increased, and that of cadmium decreased after treatment, as compared with those before treatment, the difference was significant (P < 0.05).


CONCLUSIONS
JLOL could improve and regulate the reproductive hormone disturbance in infertile patients with varicocele after varicocelectomy, enhance their quality of semen and sperm to increase the pregnancy rate of their spouses.
Yan
Le-fa
LF
Affiliated Hospital of Weifang Medical College, Shandong 261042. qdjnylf@sohu.com
Jiang
Mei-fang
MF
Shao
Rui-yun
RY
D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008517:Phytotherapy; D011182:Postoperative Care; D012661:Semen / Q000737:chemistry; D013081:Sperm Motility; D013482:Superoxide Dismutase / Q000378:metabolism; D014646:Varicocele / Q000150:complications / Q000188:drug therapy* / Q000601:surgery; D015032:Zinc / Q000378:metabolism
D004365:Drugs, Chinese Herbal; D013482:Superoxide Dismutase; D015032:Zinc