Prostate gland-like epithelium in the epididymis: a case report and review of the literature.
Aberrant prostatic tissue occurs commonly in the adult male urethra and bladder. Ectopic prostatic tissue occurring outside the urinary system is rare. One case with scattered prostate-type glands in epididymis has been reported in the literature. We report a related case, in which the presence of prostate gland-like epithelium was recognized in epididymal glands in routine histology and was confirmed by subsequent immunohistochemical analysis using prostate-specific antigen. We then examined 23 additional orchiectomy specimens for the presence of prostate-like epithelium. The possibility of this being true ectopia versus an unusual metaplastic change is discussed.
Lee
Lisa Yan-Jie
LY
Department of Pathology, Mount Sinai Medical Center, New York, NY, USA. leeli@nychhc.org
Tzeng
James
J
Grosman
Marina
M
Unger
Pamela D
PD
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers; D002648:Child; D002675:Child, Preschool; D002828:Choristoma / Q000473:pathology*; D003456:Cryptorchidism / Q000601:surgery; D004822:Epididymis / Q000473:pathology*; D004848:Epithelium / Q000648:ultrastructure; D006552:Hernia, Inguinal / Q000601:surgery; D006801:Humans; D033162:Incidental Findings; D008297:Male; D008679:Metaplasia; D008875:Middle Aged; D009919:Orchiectomy; D011467:Prostate / Q000737:chemistry; D017430:Prostate-Specific Antigen / Q000032:analysis; D012189:Retrospective Studies; D013733:Testicular Diseases / Q000473:pathology*; D013736:Testicular Neoplasms / Q000601:surgery
D015415:Biomarkers; D017430:Prostate-Specific Antigen