title: Stereoselective anti aldol reactions of erythrulose derivatives. Functionalized chiral d3 and d4 synthons.
abstract: An improved procedure for the synthesis of anti aldols from protected erythrulose derivatives is reported. The preparation of functionalized d3 and d4 synthons with various stereochemical arrays by means of this methodology is described and subsequently applied to a stereoselective formal synthesis of the natural metabolite goniothalesdiol.
authors.affiliation: Departamento de Química Inorgánica y Orgánica, and Servicios Centrales de Instrumentación, Universidad Jaume I, E-12080 Castellón, Spain.
authors.forename: Juan
authors.initials: J
authors.lastname: Murga
authors.forename: Purificación
authors.initials: P
authors.lastname: Ruiz
authors.forename: Eva
authors.initials: E
authors.lastname: Falomir
authors.forename: Miguel
authors.initials: M
authors.lastname: Carda
authors.forename: Gabriel
authors.initials: G
authors.lastname: Peris
authors.forename: J Alberto
authors.initials: JA
authors.lastname: Marco
mesh_terms: D000447:Aldehydes / Q000037:antagonists & inhibitors / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry; D007783:Lactones / Q000138:chemical synthesis; D015394:Molecular Structure; D013237:Stereoisomerism; D013780:Tetroses / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D007659:Ketones; D007783:Lactones; D013780:Tetroses; C100073:erythrulose; C116609:3-hydroxybutanal