title: Is there any hope for AIDS?
abstract: Infection by HIV-1 is characterized by genetic diversity wherein distinct viral subtypes (clades A, B, C, D, E, F, G, K and O) are expanding in different geographic regions. With respect to HIV-1 sensitivity to antiretroviral drugs and drug resistance, increasing evidence suggests that all clades probably display similar sensitivity to antiviral drugs, but viruses from some subtypes and geographic regions have a greater propensity than other viral variants to develop resistance to certain drugs. There is an urgency to make anti-HIV drugs available to all who are in need, regardless of ability to pay.
authors.affiliation: McGill University AIDS Centre, Lady Davis Institute, Sir Mortimer B. Davis-Jewish General Hospital, Montréal, Que. mark.wainberg@mcgill.ca
authors.forename: Mark A
authors.initials: MA
authors.lastname: Wainberg
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D019380:Anti-HIV Agents / Q000627:therapeutic use; D024882:Drug Resistance, Viral; D014644:Genetic Variation; D005843:Geography; D015658:HIV Infections / Q000453:epidemiology; D015497:HIV-1 / Q000235:genetics; D006801:Humans
chemical_list: D019380:Anti-HIV Agents