title: Artecoll granuloma: a rare adverse reaction induced by microimplant in the treatment of neck wrinkles.
abstract: BACKGROUND
  Artecoll is now being widely used as an injectable aesthetic microimplant for the treatment of wrinkles because of its long-lasting cosmetic effects and the rarity of late complications, including foreign body granulomas. Recently, however, several cases of Artecoll-induced granulomas on the face have been reported, especially in patients receiving overly superficial or overly correcting implants.
  
  
  RESULTS
  A 50-year-old Korean woman who had been treated with Artecoll for the correction of the neck wrinkles presented 4 years later with an extensive Artecoll-induced foreign body granuloma along the injection sites in the neck. After three intralesional injections of triamcinolone acetonide, the lesions had almost disappeared.
  
  
  CONCLUSIONS
  To our knowledge, this case is the first report of an extensive Artecoll-induced granuloma on the neck. Our findings suggest that Artecoll not be used as implant material in thin and constantly movable skin, such as that of the neck.
authors.affiliation: Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Poongnap-dong, Songpa-gu, Seoul 138-736, Korea. kimkj20@dreamwiz.com
authors.forename: Kyoung-Jin
authors.initials: KJ
authors.lastname: Kim
authors.forename: Hae-Woong
authors.initials: HW
authors.lastname: Lee
authors.forename: Mi-Woo
authors.initials: MW
authors.lastname: Lee
authors.forename: Jee-Ho
authors.initials: JH
authors.lastname: Choi
authors.forename: Kee-Chan
authors.initials: KC
authors.lastname: Moon
authors.forename: Jai-Kyoung
authors.initials: JK
authors.lastname: Koh
mesh_terms: D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D001672:Biocompatible Materials / Q000008:administration & dosage / Q000009:adverse effects*; D003094:Collagen / Q000008:administration & dosage / Q000009:adverse effects*; D003357:Cosmetic Techniques / Q000009:adverse effects; D005260:Female; D015745:Granuloma, Foreign-Body / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D015552:Injections, Intralesional; D007279:Injections, Subcutaneous; D008863:Microspheres; D008875:Middle Aged; D009333:Neck; D019904:Polymethyl Methacrylate / Q000008:administration & dosage / Q000009:adverse effects* / Q000031:analogs & derivatives*; D019736:Prostheses and Implants / Q000009:adverse effects*; D015595:Skin Aging; D016896:Treatment Outcome; D014221:Triamcinolone / Q000008:administration & dosage
chemical_list: D000893:Anti-Inflammatory Agents; C445359:Artecoll; D001672:Biocompatible Materials; D014221:Triamcinolone; D003094:Collagen; D019904:Polymethyl Methacrylate