title: [Study on effect of flavonoids from oil-removed seeds of Hippophae rhamnoides on inducing apoptosis of human hepatoma cell].
abstract: OBJECTIVE
  To investigate the inhibitory and apoptosis-inducing effects of flavonoids from oil-removed seeds of Hippophae rhamnoides (FSH) on liver cancer cell line BEL-7402.
  
  
  METHODS
  SRB, Wright staining, electron microscope and flow cytometry are used to study the effects of STT on BEL-7402 cell line.
  
  
  RESULTS
  FSH has potent inhibitive effect on BEL-7402 cell line in a concentration-dependent manner. BEL-7402 cells exhibit typical morphological alteration of apoptosis when sub-Gl peak can be seen.
  
  
  CONCLUSIONS
  FSH exerts its inhibitive effect on BEL-7402 cells by inducing apoptosis.
authors.affiliation: Life Science School of East China Normal University, Shanghai 200062.
authors.forename: Bin
authors.initials: B
authors.lastname: Sun
authors.forename: Ping
authors.initials: P
authors.lastname: Zhang
authors.forename: Weijing
authors.initials: W
authors.lastname: Qu
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Zhang
authors.forename: Xiuyuan
authors.initials: X
authors.lastname: Zhuang
authors.forename: Huangjian
authors.initials: H
authors.lastname: Yang
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects*; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005419:Flavonoids / Q000494:pharmacology*; D031281:Hippophae / Q000737:chemistry; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D010946:Plants, Medicinal / Q000737:chemistry; D012639:Seeds / Q000737:chemistry; D014407:Tumor Cells, Cultured
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D005419:Flavonoids