Recombinant t-PA in myocardial ischemia after switch operation.
A well-recognized complication of the anatomic correction (arterial switch operation) of transposition of the great arteries is obstruction of the translocated coronary arteries. Myocardial reperfusion has previously been achieved by surgical revascularization or percutaneous balloon angioplasty. We report the case of a 3-month-old infant who suffered myocardial infarction 11 weeks after the arterial switch operation, in whom myocardial reperfusion was established following infusion of recombinant tissue-type plasminogen activator (Alteplase).
Tzifa
A
A
Department of Paediatric Intensive Care Unit, Royal Brompton Hospital, London, United Kingdom. aphrodite.tzifa@gsh.sthames.nhs.uk
Joashi
U
U
Slavik
Z
Z
D015906:Angioplasty, Balloon, Coronary; D006328:Cardiac Catheterization; D017023:Coronary Angiography; D004452:Echocardiography; D006801:Humans; D007223:Infant; D008297:Male; D017202:Myocardial Ischemia / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D010960:Plasminogen Activators / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D014188:Transposition of Great Vessels / Q000628:therapy; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology
D010960:Plasminogen Activators; D010959:Tissue Plasminogen Activator