title: Multiple lymphomatous polyposis of the colon originating from T-cells: a case report.
abstract: Multiple lymphomatous polyposis is an unusual form of non-Hodgkin's lymphoma characterised by myriad polyps throughout the alimentary tract. Most multiple lymphomatous polyposis cases are derived from B-cell, and there has been little information on multiple lymphomatous polyposis of T-cell origin. A 67-year-old Japanese man presented with lower abdominal pain and diarrhoea of 4-week duration. Colonoscopy revealed numerous small umbilicated polyps and several raised erosions in the colorectum. Biopsy specimens showed diffuse proliferation of lymphoma cells negative for B-cell markers but positive for T-cell markers. Polymerase chain reaction using extracted chromosomal deoxyribonucleic acid from paraffin-embedded samples identified T-cell receptor gamma and delta gene recombination. The patient was treated with combined chemotherapy, leading to complete resolution of the lesions.
authors.affiliation: Department of Endoscopy, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki 852-8102, Japan. hajimei2002@yahoo.co.jp
authors.forename: H
authors.initials: H
authors.lastname: Isomoto
authors.forename: T
authors.initials: T
authors.lastname: Maeda
authors.forename: T
authors.initials: T
authors.lastname: Akashi
authors.forename: T
authors.initials: T
authors.lastname: Tsuchiya
authors.forename: Y
authors.initials: Y
authors.lastname: Kawaguchi
authors.forename: Y
authors.initials: Y
authors.lastname: Sawayama
authors.forename: S
authors.initials: S
authors.lastname: Koida
authors.forename: K
authors.initials: K
authors.lastname: Ohnita
authors.forename: S
authors.initials: S
authors.lastname: Kohno
authors.forename: M
authors.initials: M
authors.lastname: Tomonaga
mesh_terms: D000368:Aged; D003111:Colonic Polyps / Q000473:pathology*; D015179:Colorectal Neoplasms / Q000473:pathology*; D006801:Humans; D016399:Lymphoma, T-Cell / Q000473:pathology*; D008297:Male; D013601:T-Lymphocytes / Q000473:pathology