title: West Nile virus encephalitis in a kidney transplant recipient.
abstract: We describe a case of West Nile virus encephalitis in a 54-year-old kidney transplant recipient. The clinical course was rapid and fatal. Serial CSF samples showed an evolving mononuclear pleiocytosis and serial MRIs showed increasing signs of cytotoxic edema in her basal ganglia. Seroepidemiological testing indicated that the infection was most likely acquired from transfusion of fresh frozen plasma at the time of transplantation.
authors.affiliation: Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA. jshepha1@jhmi.edu
authors.forename: James C
authors.initials: JC
authors.lastname: Shepherd
authors.forename: Aruna
authors.initials: A
authors.lastname: Subramanian
authors.forename: Robert A
authors.initials: RA
authors.lastname: Montgomery
authors.forename: Milagros D
authors.initials: MD
authors.lastname: Samaniego
authors.forename: Gary
authors.initials: G
authors.lastname: Gong
authors.forename: Amy
authors.initials: A
authors.lastname: Bergmann
authors.forename: David
authors.initials: D
authors.lastname: Blythe
authors.forename: Lesia
authors.initials: L
authors.lastname: Dropulic
mesh_terms: D001479:Basal Ganglia / Q000000981:diagnostic imaging / Q000473:pathology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000134:cerebrospinal fluid / Q000276:immunology; D016030:Kidney Transplantation; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010949:Plasma / Q000821:virology*; D011859:Radiography; D065227:Transfusion Reaction; D014901:West Nile Fever / Q000276:immunology / Q000503:physiopathology*; D014902:West Nile virus / Q000276:immunology
chemical_list: D007075:Immunoglobulin M