title: Low prevalence of restless legs syndrome in patients with advanced chronic renal failure in the Indian population: a case controlled study.
abstract: BACKGROUND
  Restless legs syndrome (RLS) is reported to occur in 20-70% of uremic patients. There is no study from India regarding the prevalence of RLS in chronic renal failure (CRF) patients. Studies from other Asian countries have shown a much lower prevalence compared to the West. This study investigated the prevalence of RLS in patients with advanced CRF in the Indian population.
  
  
  METHODS
  Sixty-five CRF patients and 99 controls were evaluated using a predesigned standard questionnaire. The control group consisted of prospective renal donors.
  
  
  RESULTS
  The mean age of our patients was 42.4 +/- 14.9 years as compared to 43.7 +/- 11.2 years (p = NS). The distribution of cause of CRF was as follows: diabetes 38.5%, hypertension 13.9%, chronic interstitial nephritis 29.2% and chronic glomerulonephritis 18.4%. RLS was present in 1 patient (1.5%) and none of the controls.
  
  
  CONCLUSIONS
  The prevalence of RLS in CRF patients in India is very low as compared to the Western population.
authors.affiliation: Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Dipankar
authors.initials: D
authors.lastname: Bhowmik
authors.forename: Manvir
authors.initials: M
authors.lastname: Bhatia
authors.forename: Sumeet
authors.initials: S
authors.lastname: Tiwari
authors.forename: Sandeep
authors.initials: S
authors.lastname: Mahajan
authors.forename: Sanjay
authors.initials: S
authors.lastname: Gupta
authors.forename: Sanjay K
authors.initials: SK
authors.lastname: Agarwal
authors.forename: Suresh C
authors.initials: SC
authors.lastname: Dash
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007194:India / Q000453:epidemiology; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012148:Restless Legs Syndrome / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D012720:Severity of Illness Index