Fatal hemothorax due to rupture of an intrathoracic extramedullary hematopoietic nodule.
Intrathoracic extramedullary hematopoiesis (TEMH) is an unusual but well-described entity, which is typically found in patients who have chronic hemolytic anemias, myelofibrosis, or myeloproliferative disorders. It is seldom symptomatic, rarely fatal. We report a case of a 26-year-old African-American male with a past medical history of sickle cell trait/beta thalassemia who developed multiple intrathoracic nodules of extramedullary hematopoiesis. One of these nodules spontaneously ruptured and produced a fatal hemothorax.
Chute
Dennis J
DJ
Division of Neuropathology, UCLA Medical Center, Los Angeles, California 90095, USA. dchute@mednet.ucla.edu
Fowler
David R
DR
D000328:Adult; D006411:Hematopoiesis, Extramedullary / Q000502:physiology*; D006491:Hemothorax / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D012422:Rupture, Spontaneous / Q000473:pathology; D012805:Sickle Cell Trait / Q000503:physiopathology; D017086:beta-Thalassemia / Q000503:physiopathology