Ulcerative colitis followed by the development of Behçet's disease.
A 34-year-old man who had a history of ulcerative colitis (UC) was admitted to our hospital with complaints of arthralgia, erythema nodosum, recurrent oral aphthous ulcers and bloody stools. A colonoscopy revealed multiple aphthous ulcers on his cecum and colon and also revealed a transmural ulcer on his rectum consistent with a diagnosis of UC. The patient was HLA-B51 positive. Based on clinical evidence [recurrent oral ulcers, skin lesions (erythema nodosum), positivity for pathergy test] this patient was diagnosed as having Behçet's disease with gastrointestinal involvement. We describe this rare case of Behçet's disease with colitis and discuss the difficulties in making a differential diagnosis between Behçet's disease and the inflammatory bowel diseases.
Kobashigawa
Tsuyoshi
T
Institute of Rheumatology, Tokyo Women's Medical University, Tokyo.
Okamoto
Hiroshi
H
Kato
Junko
J
Shindo
Hironari
H
Imamura
Tetsuo
T
Iizuka
Bun-ei
BE
Tanaka
Masanori
M
Uesato
Masashi
M
Ohta
Shu-ji
SJ
Terai
Chihiro
C
Hara
Masako
M
Kamatani
Naoyuki
N
D000328:Adult; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis; D003093:Colitis, Ulcerative / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D012809:Colon, Sigmoid / Q000473:pathology; D003113:Colonoscopy; D006801:Humans; D008297:Male; D012007:Rectum / Q000473:pathology; D013281:Stomatitis, Aphthous / Q000150:complications