title: Plaque and saliva fluoride levels after placement of fluoride releasing pit and fissure sealants.
abstract: OBJECTIVE
  The objectives of this study were to investigate the fluoride levels in plaque and saliva before and after applying fluoride-containing pit and fissure sealants, and compare the fluoride release of 2 types of sealants at the different time intervals.
  
  
  METHODS
  Eighteen children ages 6 to 9 years were randomly divided into 2 groups: Group 1--sealant containing fluorosilicate glass (Helioseal-F); and group 2--sealant containing methacryloyl fluoride-methyl methacrylate copolymer (Teethmate-F). Saliva and plaque samples were collected before and after the sealants were placed on their 4 first permanent molars. Fluoride levels were determined using the microdiffusion method. Fluoride concentrations before and after placing the sealants were analyzed by paired t test, and the fluoride concentrations between the 2 sealants were compared by t test, with the level of significance at 0.05.
  
  
  RESULTS
  There was no significant difference between salivary fluoride levels before and after sealant placement application in both groups. The plaque fluoride level of Helioseal-F group at 24 hours was significantly higher than the baseline level (P = .03), and was not different afterwards. The plaque fluoride levels after sealant with Teethmate-F were not significantly different when compared to the baseline. However, there were no significant differences between salivary and plaque fluoride levels of the 2 groups at different time intervals.
  
  
  CONCLUSIONS
  The groups sealed with sealant containing fluorosilicate glass showed significant increase of plaque fluoride level only at 24 hours after sealant placement.
authors.affiliation: Department of Pediatric Dentistry, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
authors.forename: Daranee
authors.initials: D
authors.lastname: Rajtboriraks
authors.forename: Siriruk
authors.initials: S
authors.lastname: Nakornchai
authors.forename: Panit
authors.initials: P
authors.lastname: Bunditsing
authors.forename: Rudee
authors.initials: R
authors.lastname: Surarit
authors.forename: Piyarat
authors.initials: P
authors.lastname: Iemjarern
mesh_terms: D002327:Cariostatic Agents / Q000032:analysis* / Q000737:chemistry / Q000627:therapeutic use; D002648:Child; D003188:Composite Resins / Q000737:chemistry / Q000627:therapeutic use; D004245:DMF Index; D003773:Dental Plaque / Q000737:chemistry*; D004058:Diffusion; D005459:Fluorides / Q000032:analysis* / Q000737:chemistry / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D006863:Hydrogen-Ion Concentration; D016555:Matched-Pair Analysis; D010895:Pit and Fissure Sealants / Q000737:chemistry / Q000627:therapeutic use*; D012463:Saliva / Q000737:chemistry*; D013997:Time Factors
chemical_list: D002327:Cariostatic Agents; D003188:Composite Resins; D010895:Pit and Fissure Sealants; C099291:teethmate-FTM; C059908:Helioseal; D005459:Fluorides