title: [Mortality in children with epilepsy. A clinical prospective study].
abstract: BACKGROUND
  Mortality in patients with epilepsy is higher than the general population, but the data about children is not too extends. OBJECTIVES. To determine the risk of dying in epileptic children, the associated factors and the cause of death, as well as to target the support given to the family.
  
  
  METHODS
  From 1996 to 2002, sixteen children with epilepsy controlled in our centre died. Fifteen of them were included in our research according to a previous protocol. The data was token from our data bank, the clinical file and parents interview.
  
  
  RESULTS
  The standard mortality rate was 3.21 (95% CI: 1.48 4.95). The main group had an early onset on their illness. Thirteen children had remote symptomatic epilepsy. Eleven had resistant or catastrophic epilepsy. The EEG was specific for epilepsy in 11 cases. Nine children were receiving politherapy. Eight patients had received three or more therapeutic schemes. Eight had pre mortem therapeutic blood levels of antiepileptic drugs. Ten patients die because of infection and five because of a sudden unexpected death. In one of them the sudden unexpected death was definite and was given in a pregnant teenager with a juvenile myoclonic epilepsy. Other boy died soon after an earthquake. The assistance to the mourning elaboration was useful for the family.
  
  
  CONCLUSIONS
  This children has a high risk of dying, it is associated to on early onset of severe, active, resistant and catastrophic epilepsy. The entire control of crisis should be the main target of treatment.
authors.affiliation: Hospital de Niños Luis Calvo Mackenna, Santiago de Chile, Chile.
authors.forename: M
authors.initials: M
authors.lastname: Devilat Barros
authors.forename: G
authors.initials: G
authors.lastname: Rivera Gómez
authors.forename: V
authors.initials: V
authors.lastname: Gómez Muñoz
authors.forename: J P
authors.initials: JP
authors.lastname: Sepulveda Olmos
mesh_terms: D000293:Adolescent; D017668:Age of Onset; D000927:Anticonvulsants / Q000627:therapeutic use; D002423:Cause of Death; D002648:Child; D002675:Child, Preschool; D002677:Chile / Q000453:epidemiology; D015897:Comorbidity; D003645:Death, Sudden / Q000453:epidemiology; D004351:Drug Resistance; D004569:Electroencephalography; D004827:Epilepsy / Q000401:mortality*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007239:Infections / Q000401:mortality; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000401:mortality; D011446:Prospective Studies
chemical_list: D000927:Anticonvulsants