Targeted radiotherapy of brain tumours.
The utility of external beam radiotherapy for the treatment of malignant brain tumours is compromised by the need to avoid excessive radiation damage to normal CNS tissues. This review describes the current status of targeted radiotherapy, an alternative strategy for brain tumour treatment that offers the exciting prospect of increasing the specificity of tumour cell irradiation.
Zalutsky
M R
MR
Department of Radiology, Duke University Medical Center, PO Box 3808, Durham, NC 27710, USA. zalut001@mc.duke.edu
D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D001254:Astrocytoma / Q000532:radiotherapy*; D001932:Brain Neoplasms / Q000532:radiotherapy*; D002986:Clinical Trials as Topic; D005909:Glioblastoma / Q000532:radiotherapy*; D006801:Humans; D011832:Radiation Injuries / Q000517:prevention & control*; D016499:Radioimmunotherapy / Q000379:methods
D000911:Antibodies, Monoclonal