title: Tissue reaction to liquid silicone simulating low-grade liposarcoma following lip augmentation.
abstract: We report the case of a 32-year-old woman who underwent silicone injection into the upper lip 2 years prior to presenting with masses clinically suspicious for tumor and interpreted on biopsy as low-grade liposarcoma. Lack of pre-operative history of silicone injection almost led to unnecessary surgery. This complicated situation may arise when reaction to liquid or gel silicone histologically closely simulates a low-grade liposarcoma. Clinical and pathological correlations are of critical assistance in making the correct pre-operative diagnosis and avoiding unnecessary traumatic surgical intervention.
authors.affiliation: Department of Pathology, Hadassah University Hospital, Jersalem, Israel. maly_alex@yahoo.com
authors.forename: Alexander
authors.initials: A
authors.lastname: Maly
authors.forename: Eran
authors.initials: E
authors.lastname: Regev
authors.forename: Karen
authors.initials: K
authors.lastname: Meir
authors.forename: Bella
authors.initials: B
authors.lastname: Maly
mesh_terms: D000328:Adult; D003357:Cosmetic Techniques / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D015745:Granuloma, Foreign-Body / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008046:Lip / Q000601:surgery*; D008047:Lip Diseases / Q000139:chemically induced* / Q000473:pathology; D008048:Lip Neoplasms / Q000175:diagnosis; D008080:Liposarcoma / Q000175:diagnosis; D012828:Silicones / Q000009:adverse effects*
chemical_list: D012828:Silicones