title: Delayed reactivation of presumed adenoviral subepithelial infiltrates after laser in situ keratomileusis.
abstract: OBJECTIVE
  To report the reactivation of presumed adenoviral keratitis after laser in situ keratomileusis (LASIK).
  
  
  METHODS
  Case report and literature review.
  
  
  RESULTS
  The patient underwent uneventful LASIK more than 5 years after an episode of adenoviral keratitis that left subepithelial corneal scarring. Three months after LASIK, new subepithelial infiltrates appeared in the right eye. These lesions resolved without sequelae during treatment with topical steroids. The patient's uncorrected and best-corrected visual acuity returned to her postoperative baseline.
  
  
  CONCLUSIONS
  LASIK may cause delayed exacerbation of subepithelial infiltrates caused by adenoviral keratitis. However, good visual outcomes can be achieved with recognition of this reactivation and treatment with topical corticosteroids.
authors.affiliation: Department of Ophthalmology and Emory Vision Refractive Surgery Center, Emory University, Atlanta, GA 30319, USA. jrandle@emory.edu
authors.forename: J Bradley
authors.initials: JB
authors.lastname: Randleman
authors.forename: Susanne M
authors.initials: SM
authors.lastname: Hewitt
authors.forename: R Doyle
authors.initials: RD
authors.lastname: Stulting
mesh_terms: D000258:Adenovirus Infections, Human / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D000260:Adenoviruses, Human / Q000502:physiology*; D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D019573:Epithelium, Corneal / Q000821:virology*; D015828:Eye Infections, Viral / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007634:Keratitis / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D011239:Prednisolone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014775:Virus Activation
chemical_list: D000998:Antiviral Agents; D005938:Glucocorticoids; C009935:prednisolone acetate; D011239:Prednisolone