Chemical composition and antimicrobial activity of the essential oil of Scutellaria barbata.
The essential oil of Scutellaria barbata was obtained by hydrodistillation with a 0.3% (v/w) yield and analysed by GC and GC-MS. The main compounds in the oil were hexahydrofarnesylacetone (11.0%), 3,7,11,15-tetramethyl-2-hexadecen-1-ol (7.8%), menthol (7.7%) and 1-octen-3-ol (7.1%). The antimicrobial activity of the oil was evaluated against 17 microorganisms using disc diffusion and broth microdilution methods. The gram-positive bacteria, including methicillin-resistant Staphlococcus aureus, were more sensitive to the oil than gram-negative bacteria and yeasts.
Yu
Jianqing
J
College of Life Sciences, Wuhan University, Wuhan 430072, People's Republic of China.
Lei
Jiachuan
J
Yu
Huaidong
H
Cai
Xuan
X
Zou
Guolin
G
D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects; D041022:Candida tropicalis / Q000187:drug effects; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests / Q000379:methods; D015242:Ofloxacin / Q000494:pharmacology; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D031363:Scutellaria / Q000737:chemistry*
D000890:Anti-Infective Agents; D009822:Oils, Volatile; D015242:Ofloxacin