title: Cerebrospinal fluid pressure monitoring after repair of cerebrospinal fluid leaks.
abstract: OBJECTIVE
  To measure intracranial pressures (ICPs) via lumbar drains after surgical repair of cerebrospinal fluid (CSF) leaks.
  
  
  METHODS
  We conducted a retrospective review of ICP measurements through lumbar drains during the immediate postoperative period after CSF leak repair.
  
  
  RESULTS
  Eight patients with spontaneous CSF leaks underwent surgery and postoperative CSF pressures were measured via lumbar drains. ICP was elevated in 7/8 patients (mean, 32.5 cm H(2)O). Diuretics reduced ICP (mean, 10 cm H(2)O). Three traumatic CSF leaks patients served as controls (mean, ICP 14 cm H(2)O).
  
  
  CONCLUSIONS
  Measurement of ICP through lumbar drains provides important information regarding the pathophysiology of CSF leaks that has an impact on subsequent medical and surgical treatment. Although the precise cause and mechanism of spontaneous CSF leaks are not fully understood, this study indicates that elevated ICP plays a role and that further medical or surgical treatment to correct the intracranial hypertension may be warranted.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA. schlossr@musc.edu
authors.forename: Rodney J
authors.initials: RJ
authors.lastname: Schlosser
authors.forename: Eileen Maloney
authors.initials: EM
authors.lastname: Wilensky
authors.forename: M Sean
authors.initials: MS
authors.lastname: Grady
authors.forename: James N
authors.initials: JN
authors.lastname: Palmer
authors.forename: David W
authors.initials: DW
authors.lastname: Kennedy
authors.forename: William E
authors.initials: WE
authors.lastname: Bolger
mesh_terms: D000328:Adult; D002559:Cerebrospinal Fluid Rhinorrhea / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D006801:Humans; D019586:Intracranial Hypertension / Q000601:surgery; D007427:Intracranial Pressure; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D011184:Postoperative Period; D012189:Retrospective Studies; D013129:Spinal Puncture