title: Determination of Ochratoxin A in small volumes of human blood serum.
abstract: A new simple and rapid method for analysing Ochratoxin A (OTA) in small volumes of human blood serum using capillary zone electrophoresis coupled to laser-induced fluorescence is described. The clean-up procedure solely consists of a double extraction step. To improve the reproducibility of migration times and quantification, two internal standards were used. The limit of detection was 0.55 ng/ml, with a linear range of 1-100 ng/ml of OTA in spiked human blood serum. The method is used to rapidly screen suspected patients.
authors.affiliation: Department of Human Exposure Research and Epidemiology, Centre for Environmental Research Leipzig-Halle, Permoserstr. 15, 04318 Leipzig, Germany. gabor.koeller@ufz.de
authors.forename: G
authors.initials: G
authors.lastname: Köller
authors.forename: U
authors.initials: U
authors.lastname: Rolle-Kampczyk
authors.forename: I
authors.initials: I
authors.lastname: Lehmann
authors.forename: P
authors.initials: P
authors.lastname: Popp
authors.forename: O
authors.initials: O
authors.lastname: Herbarth
mesh_terms: D006801:Humans; D009183:Mycotoxins / Q000097:blood*; D009793:Ochratoxins / Q000097:blood*; D012015:Reference Standards; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D009183:Mycotoxins; D009793:Ochratoxins; C025589:ochratoxin A