Linear IgA disease presenting as desquamative gingivitis: a pattern poorly recognized in medicine.
Linear IgA disease is a subepidermal blistering disorder of unknown cause. Along with dermatologic blistering, other manifestations include oral ulceration and desquamative gingivitis. We present a case of linear IgA disease that manifested simply as oropharyngeal ulceration and desquamative gingivitis, resulting in considerable delay in diagnosis and treatment. This article (1) highlights the difficulties of diagnosing linear IgA disease when the predominant presenting features are mucosal and (2) reviews the current literature regarding linear IgA disease.
O'Regan
Esther
E
Department of Oral Surgery, Oral Medicine, and Oral Pathology, Dublin Dental School and Hospital, Ireland.
Bane
Anita
A
Flint
Stephen
S
Timon
Conrad
C
Toner
Mary
M
D001327:Autoimmune Diseases / Q000276:immunology / Q000473:pathology*; D001485:Basement Membrane / Q000276:immunology / Q000473:pathology; D001706:Biopsy; D003937:Diagnosis, Differential; D019084:Fluorescent Antibody Technique, Indirect; D005881:Gingiva / Q000473:pathology; D005891:Gingivitis / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000276:immunology / Q000473:pathology; D019226:Oral Ulcer / Q000276:immunology / Q000473:pathology*
D007070:Immunoglobulin A