title: Anaesthesia for a patient with Leigh's syndrome undergoing surgery for scoliosis.
abstract: Anaesthesia for patients with Leigh's syndrome has rarely been reported. Leigh's syndrome or subacute necrotizing encephalomyelopathy is a neurodegenerative disorder of infancy or childhood. Acute exacerbation with respiratory failure may accompany surgery and general anaesthesia. In this case report we describe the anaesthetic management of a 17 year old patient scheduled for spine surgery.
authors.affiliation: Department of Anaesthesiology, Gent University Hospital, De Pintelaan, 185, 9000 Gent, Belgium. tom.jacobs@UGent.be
authors.forename: T F
authors.initials: TF
authors.lastname: Jacobs
authors.forename: F S
authors.initials: FS
authors.lastname: Plasschaert
authors.forename: G P
authors.initials: GP
authors.lastname: Bossuyt
authors.forename: L L
authors.initials: LL
authors.lastname: Szegedi
authors.forename: L L
authors.initials: LL
authors.lastname: Herregods
mesh_terms: D000293:Adolescent; D000768:Anesthesia, General; D018685:Anesthetics, Inhalation / Q000008:administration & dosage; D018686:Anesthetics, Intravenous / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007888:Leigh Disease / Q000150:complications*; D008738:Methyl Ethers / Q000008:administration & dosage; D016343:Monitoring, Intraoperative; D009609:Nitrous Oxide / Q000008:administration & dosage; D010100:Oxygen / Q000008:administration & dosage; D010880:Piperidines / Q000008:administration & dosage; D015742:Propofol / Q000008:administration & dosage; D000077208:Remifentanil; D012121:Respiration, Artificial; D012600:Scoliosis / Q000601:surgery*; D000077149:Sevoflurane
chemical_list: D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D008738:Methyl Ethers; D010880:Piperidines; D000077149:Sevoflurane; D009609:Nitrous Oxide; D000077208:Remifentanil; D010100:Oxygen; D015742:Propofol