Adenoid cystic carcinoma associated with salivary duct cyst in the sublingual gland.
We described an extremely rare case of adenoid cystic carcinoma associated with salivary duct cyst in the sublingual gland of a 40-year-old Japanese woman. The tumor was growing from the cyst wall and almost occluded the cyst lumen. The epithelium lining the cyst lumen contained both keratin 19-positive cells and alpha-smooth muscle actin-positive cells, indicating the cyst being derived from the acinus/intercalated duct of the sublingual gland. Therefore, our case has presented for the first time a direct evidence that adenoid cystic carcinoma arises from acinus/intercalated duct.
Ogawa
Yuzo
Y
Department of Oral Pathology, Osaka University Graduate School of Dentistry, Osaka, Japan. ogawa@dent.oska-u.ac.jp
Kishino
Mitsunobu
M
Nakazawa
Mitsuhiro
M
Iwai
Soichi
S
Ohta
Yoshiyuki
Y
Ishida
Takeshi
T
Yura
Yoshiaki
Y
Ijuhin
Naokuni
N
D000328:Adult; D003528:Carcinoma, Adenoid Cystic / Q000209:etiology* / Q000473:pathology; D003560:Cysts / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D018987:Salivary Ducts / Q000473:pathology; D012466:Salivary Gland Diseases / Q000150:complications / Q000473:pathology; D013361:Sublingual Gland / Q000473:pathology; D013362:Sublingual Gland Neoplasms / Q000209:etiology* / Q000473:pathology