title: Kumada-Corriu reactions of alkyl halides with alkynyl nucleophiles.
abstract: [reaction: see text] Pd(2)(dba)(3)-Ph(3)P-catalyzed Kumada-Corriu coupling reactions of unactivated alkyl bromides or iodides with an alkynyl nucleophile furnish C(sp)-C(sp)3 bond formation. Alkynyl nucleophiles can be alkynyllithiums or the corresponding Grignard reagents. The superior performance of Ph(3)P ligand over the trialkylphosphine ligands indicates that this cross-coupling reaction may be a reductive-elimination-controlled process.
authors.affiliation: Department of Chemistry and Institute of Polymer Science and Engineering, National Taiwan University, Taipei, Taiwan.
authors.forename: Lian-Ming
authors.initials: LM
authors.lastname: Yang
authors.forename: Li-Fu
authors.initials: LF
authors.lastname: Huang
authors.forename: Tien-Yau
authors.initials: TY
authors.lastname: Luh