title: In vitro susceptibility of 21 antimicrobial agents to 37 isolates of Brachyspira hyodysenteriae isolated from pigs in Okinawa Prefecture.
abstract: The in vitro susceptibilities to 21 antimicrobial agents, of 37 isolates of Brachyspira (B.) hyodysenteriae isolated from pigs in Okinawa meat center and a pig farm in Okinawa Prefecture, Japan, were determined by the agar dilution method. Carbadox was the most active of all the agents tested against the isolates (MIC: <0.003 to 0.05). All the isolates were highly susceptible to olaquindox, tiamulin, dimetridazole, efrotomycin and valnemulin with MICs ranging from </=0.1 to 1.6 microg/ml. Penicillins, chloramphenicol, tetracyclines, terdecamycin and streptomycin were also active against the isolates. Most isolates were resistant to lincomycin, avilamycin and macrolides (with the exception of terdecamycin).
authors.affiliation: Animal Health Laboratory, School of Agriculture, Ibaraki University, Ami, Japan.
authors.forename: Kayo
authors.initials: K
authors.lastname: Uezato
authors.forename: Eiki
authors.initials: E
authors.lastname: Kinjo
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Adachi
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002218:Carbadox; D024881:Drug Resistance, Bacterial / Q000502:physiology*; D066298:In Vitro Techniques; D007564:Japan; D008826:Microbial Sensitivity Tests; D013143:Spirochaetaceae / Q000187:drug effects*; D034421:Sus scrofa / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D002218:Carbadox