title: Fetal cardiac troponin I in relation to intrapartum events and umbilical artery pH.
abstract: The objective of this study was to measure fetal cardiac troponin I in umbilical artery blood in relation to intrapartum events and umbilical artery pH. Umbilical artery blood samples were obtained after delivery from 110 infants and cardiac troponin I was measured. The onset of labor, mode of delivery, presence of meconium, and umbilical artery pH were examined in relation to cardiac troponin I. The median cardiac troponin I level was 0.03 ng/mL (range, 0.03 to 0.881 ng/mL). Neonates with a cardiac troponin I level above the normal range had a lower umbilical artery pH when compared with those neonates with a normal cardiac troponin I level (p = 0.005). No relationship between the following parameters and cardiac troponin I was observed: gestational age, parity, presence of labor, meconium staining, mode of delivery, birth weight, and Apgar scores. Fetal cardiac troponin I shows little variation at birth. Increased levels of cardiac troponin I are associated with a lower umbilical artery pH.
authors.affiliation: Department of Obstetrics and Gynaecology, University Hospital Galway, Galway, Ireland.
authors.forename: Fionnuala
authors.initials: F
authors.lastname: McAuliffe
authors.forename: Katrina
authors.initials: K
authors.lastname: Mears
authors.forename: Sean
authors.initials: S
authors.lastname: Fleming
authors.forename: Helen
authors.initials: H
authors.lastname: Grimes
authors.forename: John J
authors.initials: JJ
authors.lastname: Morrison
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D036861:Delivery, Obstetric; D005260:Female; D005312:Fetal Blood / Q000378:metabolism; D005316:Fetal Distress / Q000097:blood*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn / Q000097:blood*; D011237:Predictive Value of Tests; D011247:Pregnancy; D011446:Prospective Studies; D019210:Troponin I / Q000097:blood*
chemical_list: D015415:Biomarkers; D019210:Troponin I