title: Effect of 1-piece and 3-piece AcrySof intraocular lenses on the development of posterior capsule opacification after cataract surgery.
abstract: OBJECTIVE
  To evaluate the effect of 1-piece and 3-piece hydrophobic acrylic intraocular lenses (IOLs) on posterior capsule opacification (PCO) after cataract surgery.
  
  
  METHODS
  Ophthalmology departments of 3 hospitals in the United Kingdom and Germany and the Department of Physics at a United Kingdom university.
  
  
  METHODS
  A series of 131 patients having cataract surgery had implantation of an acrylic 1-piece (SA30AL) or an acrylic 3-piece (MA30BA) IOL (AcrySof, Alcon). Surgery was performed according to standardized protocol by a single surgeon at each hospital. Posterior capsule opacification was assessed using digital retroillumination photography. All images were analyzed at a single center according to a standard protocol. Data were analyzed 6 months and 1 year after surgery.
  
  
  RESULTS
  There was no statistically significant difference in the percentage area of PCO between the 1-piece (mean 16.0% +/- 15.7% [SD]) and 3-piece (mean 13.6% +/- 19.8%) cohorts 6 months and 1 year after surgery (P =.0664).
  
  
  CONCLUSIONS
  There was no evidence of a difference in the area of PCO after cataract surgery between 1-piece and 3-piece IOLs, which were otherwise matched for material and lens geometry.
authors.affiliation: St. Thomas' Hospital, London SE1 7EH, United Kingdom.
authors.forename: Lloyd E
authors.initials: LE
authors.lastname: Bender
authors.forename: Christoph
authors.initials: C
authors.lastname: Nimsgern
authors.forename: Romina
authors.initials: R
authors.lastname: Jose
authors.forename: Hari
authors.initials: H
authors.lastname: Jayaram
authors.forename: David J
authors.initials: DJ
authors.lastname: Spalton
authors.forename: Manfred R
authors.initials: MR
authors.lastname: Tetz
authors.forename: Richard B
authors.initials: RB
authors.lastname: Packard
authors.forename: William
authors.initials: W
authors.lastname: Meacock
authors.forename: James
authors.initials: J
authors.lastname: Boyce
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D001672:Biocompatible Materials; D002386:Cataract / Q000209:etiology*; D005500:Follow-Up Studies; D006801:Humans; D007903:Lens Capsule, Crystalline / Q000473:pathology*; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular / Q000009:adverse effects*; D018918:Phacoemulsification; D011183:Postoperative Complications; D011474:Prosthesis Design
chemical_list: D000180:Acrylic Resins; D001672:Biocompatible Materials