Familial congenital brachial palsy: a report of two affected Egyptian families.
Congenital brachial palsy is still a relatively common birth defect and almost a sporadic disorder. This work presents 2 unrelated Egyptian families; had several members in successive generations with severe unilateral congenital brachial palsy. Pedigree analysis of both families and the high rate of consanguinity among them are highly suggestive of autosomal recessive inheritance with variable expression.
Zaki
M S
MS
National Research Center, Department of Clinical Genetics, Human Genetics and Genome Research Unit, El-Tahrir Street, Dokki, Cairo, Egypt. mszaki60@internetegypt.com
el Sabbagh
M H
MH
Aglan
M S
MS
D002648:Child; D041321:Chromosomes, Human, X / Q000235:genetics; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D009185:Myelin Proteins / Q000235:genetics*; D010291:Paresis / Q000175:diagnosis / Q000235:genetics* / Q000503:physiopathology; D010375:Pedigree; D034941:Upper Extremity / Q000294:innervation / Q000503:physiopathology
D009185:Myelin Proteins; C073687:PMP22 protein, human