The investigation of an equilibrium dependent reaction for the formation of enamines in a microchemical system.
The paper describes the equilibrium dependant reaction for the formation of enamines in a microchemical system utilising electroosmotic flow (EOF) for fluid mobilisation. The authors have shown that the reaction can be carried out without the presence of a Lewis acid catalyst, in addition the enamine intermediate was synthesised at room temperature using mild solvent conditions. A 42% conversion of cyclohexanone into the enamine has been achieved to date.
Sands
M
M
Department of Chemistry, Faculty of Science and the Environment, University of Hull, Cottingham Road, Hull, UKHU6 7RX.
Haswell
S J
SJ
Kelly
S M
SM
Skelton
V
V
Morgan
D O
DO
Styring
P
P
Warrington
B
B