title: Injected calcium sulfate for consolidation of distraction osteogenesis in rabbit tibia.
abstract: This study investigated the effects of calcium sulfate powder injection in a rabbit tibial distraction model. There was one experimental group and two control groups. The calcium sulfate powder, suspended in carboxymethylcellulose (CMC) medium, was injected into the distracted tissue in the experimental rabbit group, whereas only CMC medium was injected into the one control group. The other control group did not undergo any intervention. On radiography and bone mineral density tests, the amount of newly formed bone was greater in the distracted zone of the experimental group than in the two control groups, which showed incomplete bone deposition and calcification. The application of calcium sulfate to distracted tissue increased the rate of osteogenesis and calcification.
authors.affiliation: Department of Orthopedic Surgery, Gyeongsang National University Hospital, Chinju, South Korea.
authors.forename: Hae-Ryong
authors.initials: HR
authors.lastname: Song
authors.forename: Chang-Wug
authors.initials: CW
authors.lastname: Oh
authors.forename: Hee-Soo
authors.initials: HS
authors.lastname: Kyung
authors.forename: Il-Hyung
authors.initials: IH
authors.lastname: Park
authors.forename: Poong-Taek
authors.initials: PT
authors.lastname: Kim
authors.forename: Seung-Hoon
authors.initials: SH
authors.lastname: Baek
authors.forename: Sung-Jung
authors.initials: SJ
authors.lastname: Kim
authors.forename: Sung-Tae
authors.initials: ST
authors.lastname: Lee
mesh_terms: D000818:Animals; D015519:Bone Density; D018786:Bone Substitutes / Q000494:pharmacology*; D002113:Calcification, Physiologic / Q000187:drug effects / Q000502:physiology; D002133:Calcium Sulfate / Q000494:pharmacology*; D007267:Injections; D023421:Models, Animal; D010012:Osteogenesis / Q000187:drug effects / Q000502:physiology; D019857:Osteogenesis, Distraction / Q000379:methods*; D011817:Rabbits; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging / Q000601:surgery*
chemical_list: D018786:Bone Substitutes; D002133:Calcium Sulfate