title: Right ventricular outflow tract placement of defibrillation leads: five year experience.
abstract: Over a 5-year period, 112 patients (89 male/23 female, mean age 65 years) underwent right ventricular outflow tract (RVOT) placement of permanent active-fixation transvenous pacing/defibrillating leads. At implantation, the pacing threshold was 0.6 +/- 0.3 V at 0.5 ms pulse duration and R wave amplitude was 10.9 +/- 4.9 mV. The defibrillation threshold (DFT) of right-sided implants was 17.7 +/- 3.4 J while that of left-sided implants was 16.1 +/- 3.3 J. Patients were followed at 1 and 3 month postimplant and at six-month intervals thereafter. At mean follow-up of 22.5 +/- 17.5 months (range 1-47 months) there were no lead dislodgments, unsuccessful shock therapies, or failure to sense or pace for bradycardia or tachycardia. Death was not sudden in the 17 patients who died. We conclude that RVOT pacing-defibrillation lead implantation is safe, efficacious, and potentially attractive because preliminary evidence suggests that it may not be associated with the adverse hemodynamic effects of pacing at the right ventricular apex.
authors.affiliation: Division of Cardiology, Genesis Heart Institute, Davenport, Iowa 52803, USA. giudici@cvmedpc.com
authors.forename: Michael C
authors.initials: MC
authors.lastname: Giudici
authors.forename: S Serge
authors.initials: SS
authors.lastname: Barold
authors.forename: Deborah L
authors.initials: DL
authors.lastname: Paul
authors.forename: Phillip E
authors.initials: PE
authors.lastname: Schrumpf
authors.forename: Kent J
authors.initials: KJ
authors.lastname: Van Why
authors.forename: David W
authors.initials: DW
authors.lastname: Orias
mesh_terms: D000328:Adult; D000368:Aged; D002304:Cardiac Pacing, Artificial / Q000379:methods; D009202:Cardiomyopathies / Q000628:therapy; D017147:Defibrillators, Implantable; D004554:Electric Countershock / Q000379:methods; D004562:Electrocardiography; D005260:Female; D006352:Heart Ventricles; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial