title: A plug and play microfluidic device.
abstract: Chip-to-world interface is a major issue in the field of microfluidics and its applications. We developed a plug and play microfluidic device composed of a fluid driving unit and a polymer chip containing microfluidic channels and reservoirs. The one and only connection of the device to the external world is a set of electric control lines for the driving unit. Just putting the reagents and samples onto the reservoirs, the chip can be operated for chemical or biochemical reaction and analysis. We demonstrate here that silicon-based micropumps embedded in the present device allow us to achieve flexible fluidic manipulations with minimum time delay and dead volume.
authors.affiliation: Institute of Industrial Science, University of Tokyo, 4-6-1 Komaba Meguro-ku, Tokyo 153-8505, Japan. tfujii@iis.u-tokyo.ac.jp
authors.forename: Teruo
authors.initials: T
authors.lastname: Fujii
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Sando
authors.forename: Kusunoki
authors.initials: K
authors.lastname: Higashino
authors.forename: Yasuhisa
authors.initials: Y
authors.lastname: Fujii
mesh_terms: D000818:Animals; D004058:Diffusion; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D004581:Electronics; D004867:Equipment Design; D049454:Firefly Luciferin / Q000378:metabolism; D007700:Kinetics; D008156:Luciferases / Q000378:metabolism; D008163:Luminescent Measurements; D044085:Microfluidics / Q000295:instrumentation* / Q000379:methods; D012828:Silicones / Q000737:chemistry
chemical_list: D004129:Dimethylpolysiloxanes; D012828:Silicones; D049454:Firefly Luciferin; C013830:baysilon; D008156:Luciferases