title: Intestinal transplantation for chronic intestinal pseudo-obstruction in adult patients.
abstract: Intestinal transplantation (ITx) has become a life-saving procedure for patients with irreversible intestinal failure who can no longer be maintained on parenteral nutrition (PN). This report presents the results of our experience on ITx in patients suffering from chronic intestinal pseudo-obstruction (CIPO). Between December 30, 2000 and May 30, 2003 six adult patients affected by CIPO underwent primary ITx at our Center. Pre-transplant evaluation, indication for ITx and surgical technique are reported. On December 30 2003, the mean follow-up was 25.0 months. No peri-operative deaths occurred in the study population and five out of six patients are alive, with 1-year patient and graft survival of 83.3% and 66.6%. Although our series is limited by the number of patients, our experience suggests that ITx transplantation should be considered in adult patients suffering from CIPO and PN life-threatening complication.
authors.affiliation: University of Modena and Reggio Emilia, Liver and Multivisceral Transplant Center, Modena, Italy. masetti.michele@unimo.it
authors.forename: Michele
authors.initials: M
authors.lastname: Masetti
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Di Benedetto
authors.forename: Nicola
authors.initials: N
authors.lastname: Cautero
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Stanghellini
authors.forename: Roberto
authors.initials: R
authors.lastname: De Giorgio
authors.forename: Augusto
authors.initials: A
authors.lastname: Lauro
authors.forename: Bruno
authors.initials: B
authors.lastname: Begliomini
authors.forename: Antonio
authors.initials: A
authors.lastname: Siniscalchi
authors.forename: Loris
authors.initials: L
authors.lastname: Pironi
authors.forename: Rosanna
authors.initials: R
authors.lastname: Cogliandro
authors.forename: Antonio D
authors.initials: AD
authors.lastname: Pinna
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000401:mortality / Q000601:surgery* / Q000628:therapy; D007421:Intestine, Small / Q000637:transplantation*; D008297:Male