title: Virus-associated hemophagocytic syndrome and hemorrhagic jejunal ulcer caused by cytomegalovirus infection in a non-compromised host; a case report of unusual entity.
abstract: A 76-year-old man was admitted to our hospital with abdominal pain, nausea, and vomiting. The patient was diagnosed as ileus by abdominal radiography, which showed an enlarged bowel and an air-fluid level. Computed tomography of the abdomen showed a thickened intestinal wall. His general status suddenly worsened, and he was placed on a respirator and catecholamines to prevent acute respiratory distress syndrome, septic shock, and disseminated intravascular coagulation. He had continuous fresh anal bleeding. Total colonoscopy showed bloody stool originating from the ileum. Emergency operation was performed for hemorrhagic shock under general anesthesia. Intraoperative jejunal endoscopy revealed deep linear ulcers with bleeding in the jejunum, and 30 cm of the jejunum was resected. Histopathologic examination revealed cytomegalic cells with intranuclear inclusion bodies in the tissues surrounding the ulcers, and it was diagnosed as cytomegaloviral enterocolitis with hemophagocytic syndrome in a non-compromised adult.
authors.affiliation: Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.
authors.forename: Shinomi
authors.initials: S
authors.lastname: Ina
authors.forename: Masaji
authors.initials: M
authors.lastname: Tani
authors.forename: Katsunari
authors.initials: K
authors.lastname: Takifuji
authors.forename: Shinji
authors.initials: S
authors.lastname: Yamazoe
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Nakatani
authors.forename: Hiroki
authors.initials: H
authors.lastname: Yamaue
mesh_terms: D000368:Aged; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000473:pathology; D016099:Endoscopy, Gastrointestinal; D004760:Enterocolitis / Q000150:complications* / Q000175:diagnosis / Q000821:virology*; D015616:Histiocytosis, Non-Langerhans-Cell / Q000821:virology*; D006801:Humans; D007579:Jejunal Diseases / Q000150:complications / Q000175:diagnosis; D008297:Male; D012771:Shock, Hemorrhagic / Q000209:etiology / Q000601:surgery; D014456:Ulcer / Q000150:complications / Q000175:diagnosis