title: [Distribution of calcitonin gene-related peptide in guinea pig cochlea].
abstract: OBJECTIVE
  To observe the distribution of CGRP in guinea pig cochlea.
  
  
  METHODS
  CGRP was labeled by immunostaning technique. Distribution of CGRP immunoreactivity was observed with light microscopy.
  
  
  RESULTS
  CGRP immunoreactivity was located in SGN, nerve fibers at osseous spiral lamina, stria vascularis, IHC, adjacent area of OHC and Deiters' cells.
  
  
  CONCLUSIONS
  CGRP distributes extensively in guinea pig cochlea. CGRP may play an important role as neurotransmitter and/or neuromodulator to hearing function by modulating HC, supporting cells, SGN and other neurons along the process of auditory nerve. It may have effect on on cochlear blood flow, too.
authors.affiliation: Department of Otolaryngology, First People's Hospital of Yunnan Province, Kunming, 650001, China.
authors.forename: Benming
authors.initials: B
authors.lastname: Qi
authors.forename: Xiang
authors.initials: X
authors.lastname: Huang
authors.forename: Liangru
authors.initials: L
authors.lastname: Zhu
authors.forename: Xinghua
authors.initials: X
authors.lastname: Tian
authors.forename: Jibao
authors.initials: J
authors.lastname: Wang
mesh_terms: D000818:Animals; D015740:Calcitonin Gene-Related Peptide / Q000378:metabolism*; D003051:Cochlea / Q000098:blood supply / Q000378:metabolism*; D005260:Female; D006168:Guinea Pigs; D007760:Labyrinth Supporting Cells / Q000378:metabolism; D008297:Male; D013137:Spiral Lamina / Q000378:metabolism*; D013316:Stria Vascularis / Q000378:metabolism*
chemical_list: D015740:Calcitonin Gene-Related Peptide