Cost-effectiveness of lumbar fusion and nonsurgical treatment for chronic low back pain in the Swedish Lumbar Spine Study: a multicenter, randomized, controlled trial from the Swedish Lumbar Spine Study Group.
METHODS
A cost-effectiveness study was performed from the societal and health care perspectives.


OBJECTIVE
To evaluate the costs-effectiveness of lumbar fusion for chronic low back pain (CLBP) during a 2-year follow-up.


BACKGROUND
A full economic evaluation comparing costs related to treatment effects in patients with CLBP is lacking.


METHODS
A total of 284 of 294 patients with CLBP for at least 2 years were randomized to either lumbar fusion or a nonsurgical control group. Costs for the health care sector (direct costs), and costs associated with production losses (indirect costs) were calculated. Societal total costs were identified as the sum of direct and indirect costs. Treatment effects were measured using patient global assessment of improvement, back pain (VAS), functional disability (Owestry), and return to work.


RESULTS
The societal total cost per patient (standard deviations) in the surgical group was significantly higher than in the nonsurgical group: Swedish kroner (SEK) 704,000 (254,000) vs. SEK 636,000 (208,000). The cost per patient for the health care sector was significantly higher for the surgical group, SEK 123,000 (60,100) vs. 65,200 (38,400) for the control group. All treatment effects were significantly better after surgery. The incremental cost-effectiveness ratio (ICER), illustrating the extra cost per extra effect unit gained by using fusion instead of nonsurgical treatment, were for improvement: SEK 2,600 (600-5,900), for back pain: SEK 5,200 (1,100-11,500), for Oswestry: SEK 11,300 (1,200-48,000), and for return to work: SEK 4,100 (100-21,400).


CONCLUSIONS
For both the society and the health care sectors, the 2-year costs for lumbar fusion was significantly higher compared with nonsurgical treatment but all treatment effects were significantly in favor of surgery. The probability of lumbar fusion being cost-effective increased with the value put on extra effect units gained by using surgery.
Fritzell
Peter
P
Department of Orthopedic Surgery, Falun Hospital, Falun, Sweden. peter.fritzell@ltdalarna.se
Hägg
Olle
O
Jonsson
Dick
D
Nordwall
Anders
A
D000328:Adult; D000368:Aged; D002908:Chronic Disease / Q000191:economics; D003362:Cost-Benefit Analysis / Q000706:statistics & numerical data; D004185:Disability Evaluation; D006801:Humans; D017116:Low Back Pain / Q000191:economics / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000601:surgery*; D008875:Middle Aged; D010043:Outcome and Process Assessment, Health Care / Q000706:statistics & numerical data*; D010147:Pain Measurement / Q000706:statistics & numerical data; D012680:Sensitivity and Specificity; D018582:Sick Leave / Q000191:economics / Q000706:statistics & numerical data; D013123:Spinal Fusion / Q000191:economics*; D013548:Sweden; D016896:Treatment Outcome