Sweet's syndrome and a Mirena intrauterine system.
A woman fitted with a Mirena intrauterine system (IUS) for menorrhagia presented with a short history of fever and progressive skin lesions. Histological examination of a skin biopsy was compatible with the clinical diagnosis of Sweet's syndrome. Treatment was with topical and oral steroids, however the condition relapsed on reduction of the steroid dose. Symptoms finally resolved on removal of the IUS and the patient remained symptom free at 9-month follow-up. There have been previous reports of Sweet's syndrome in association with hormonal contraceptives, however this is believed to be the first reported case in association with a Mirena IUS.
Hamill
Matthew
M
Department of Genitourinary Medicine, St Mary's Hospital, Praed Street, London, UK. matthew.hamill@st-marys.nhs.uk
Bowling
Jonathan
J
Vega-Lopez
F
F
D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002990:Clobetasol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003271:Contraceptive Agents, Female / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007436:Intrauterine Devices, Medicated / Q000009:adverse effects*; D008595:Menorrhagia / Q000188:drug therapy*; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D016463:Sweet Syndrome / Q000139:chemically induced* / Q000188:drug therapy* / Q000473:pathology
D000893:Anti-Inflammatory Agents; D003271:Contraceptive Agents, Female; D011239:Prednisolone; D002990:Clobetasol