[Plasma levels of mediator amino acids in patients with Parkinson disease].
Content of neurotransmitter amino acids before and after treatment with He-Ne-laser was measured in blood of two groups of the Parkinson's disease patients distinguished by low (first group) and high (second group) activity of monoamine oxidase B and Cu/Zn-superoxide dismutase. An increase in taurine level at the early stage of the disease (first group of patients) suggests that taurine may be a marker of compensatory abilities of the organism. The violation of the glutamate/taurine balance at the later stages of the disease and its normalization following the laserotherapy accompanied improvement of neurological symptoms.
Vitreshchak
T V
TV
Institute of Neurology, Russian Academy of Medical Sciences, Volokolamskoe Shosse 80, 125367 Moscow, Russia.
Poleshchuk
V V
VV
Piradov
M A
MA
D005260:Female; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D008995:Monoamine Oxidase / Q000097:blood; D018377:Neurotransmitter Agents / Q000097:blood*; D010300:Parkinson Disease / Q000097:blood* / Q000628:therapy; D013482:Superoxide Dismutase / Q000097:blood
D018377:Neurotransmitter Agents; D013482:Superoxide Dismutase; D008995:Monoamine Oxidase