title: Predictors of death during 10 years after coronary artery bypass grafting with particular emphasis on age.
abstract: OBJECTIVE
  To describe predictors of death during 10 years of follow-up after coronary artery bypass grafting (CABG); to evaluate whether age interacts with the influence of various predictors on outcome; and to compare the mortality during 10 years after CABG with the mortality in an age- and sex-matched control population.
  
  
  METHODS
  Prospective, observational study.
  
  
  METHODS
  Department of Thoracic and Cardiovascular Surgery at Sahlgrenska University Hospital and Scandinavian Heart Centre in Göteborg, Sweden.
  
  
  METHODS
  All patients from western Sweden who underwent CABG between 1 June 1988 and 1 June 1991 without simultaneous valve surgery and with no previous CABG.
  
  
  METHODS
  All-cause mortality during 10 years but more than 30 days after CABG.
  
  
  RESULTS
  In all, 2000 patients participated in the survey. The following factors appeared as independent predictors of death: preoperative factors-age, history of congestive heart failure, cerebrovascular disease, history of intermittent claudication, current smoking, degree of left ventricular impairment, valvular disease and duration of angina pectoris; peroperative factors-ventilator time and neurological complications; postoperative factors-arrhythmia, requirement of digitalis and requirement of antidiabetics. There was an interaction between age and history of cerebrovascular disease with a stronger impact on outcome in younger patients. The late (>30 days after CABG) 10-year mortality in the study cohort was 29.6% compared with 25.9% in the control population (P=0.02).
  
  
  CONCLUSIONS
  Among patients who underwent CABG, 13 independent predictors for mortality were found, mainly among preoperative factors but also among peroperative factors, postoperative complications and medication requirement after CABG.
authors.affiliation: Division of Cardiology, Sahlgrenska University Hospital, Göteborg, Sweden. johan.herlitz@hjl.gu.se
authors.forename: Johan
authors.initials: J
authors.lastname: Herlitz
authors.forename: Gunnar
authors.initials: G
authors.lastname: Brandrup-Wognsen
authors.forename: Kenneth
authors.initials: K
authors.lastname: Caidahl
authors.forename: Maria
authors.initials: M
authors.lastname: Haglid
authors.forename: Björn W
authors.initials: BW
authors.lastname: Karlson
authors.forename: Marianne
authors.initials: M
authors.lastname: Hartford
authors.forename: Thomas
authors.initials: T
authors.lastname: Karlsson
authors.forename: Helén
authors.initials: H
authors.lastname: Sjöland
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D001026:Coronary Artery Bypass / Q000401:mortality*; D003327:Coronary Disease / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality*; D011237:Predictive Value of Tests; D016016:Proportional Hazards Models; D012307:Risk Factors; D017678:Sex Distribution; D013548:Sweden / Q000453:epidemiology; D013997:Time Factors