Acquired factor VIII inhibitor presenting as a tongue hematoma.
Acquired hemophilia is a rare disorder that has potentially disastrous consequences if not recognized and treated in the setting of acute hemorrhage. We report a case of undiagnosed acquired hemophilia due to factor VIII inhibitor in which a tongue hematoma was the chief manifestation. Diagnosis, acute management, and long-term therapeutic options are reviewed.
Wendell
Catherine M
CM
Section of Emergency Medicine, University of Chicago, Chicago, Illinois, USA.
Bellazzini
Marc A
MA
Howes
David S
DS
D000368:Aged; D001779:Blood Coagulation Factors / Q000627:therapeutic use; D005169:Factor VIII / Q000037:antagonists & inhibitors*; D005260:Female; D006406:Hematoma / Q000209:etiology*; D006467:Hemophilia A / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D010314:Partial Thromboplastin Time; D014060:Tongue Diseases / Q000209:etiology*
D001779:Blood Coagulation Factors; C025667:prothrombin complex concentrates; D005169:Factor VIII