title: Cerebral infarction as a complication of nephrotic syndrome: a case report with a review of the literature.
abstract: Arterial thrombosis is relatively rare compared with venous thrombosis in nephrotic syndrome. However, the assessment of its pathogenesis and risk factors in individual patient with nephrotic syndrome is necessary to allow appropriate prophylactic management because it is a potentially serious problem. Hereby, with review of the literature, we report a case of a 53 yr-old man with cerebral infarction associated with nephrotic syndrome due to focal segmental glomerulosclerosis during the course of treatments with diuretics and steroid. It reveals that the hypercoagulable state in nephrotic syndrome can be associated with cerebral infarction in adults. Prophylactic anticoagulants can be considered to reduce the risk of serious cerebral infarction in nephrotic patients with risk factors such as severe hypoalbuminemia and on diuretics or steroid treatment, even in young patients regardless of types of underlying glomerular diseases.
authors.affiliation: Department of Internal Medicine, Hanyang University, Seoul, Korea.
authors.forename: Yeo Wook
authors.initials: YW
authors.lastname: Yun
authors.forename: Sungjin
authors.initials: S
authors.lastname: Chung
authors.forename: Sun-Jin
authors.initials: SJ
authors.lastname: You
authors.forename: Dong Kyu
authors.initials: DK
authors.lastname: Lee
authors.forename: Kyu-Yong
authors.initials: KY
authors.lastname: Lee
authors.forename: Sang-Woong
authors.initials: SW
authors.lastname: Han
authors.forename: Heng Ok
authors.initials: HO
authors.lastname: Jee
authors.forename: Ho-Jung
authors.initials: HJ
authors.lastname: Kim
mesh_terms: D002544:Cerebral Infarction / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000150:complications* / Q000453:epidemiology; D012307:Risk Factors