title: [Anti-inflammatory effect of arglabin and 11,13-dihydro-13-dimethylaminoarglabin hydrochloride].
abstract: The sesquiterpene lactone arglabin, as well as its derivative 11,13-Dihydro-13-dimethylaminoarglabin hydrochloride, exhibit antiexudative and antiproliferative properties on the models of acute aseptic inflammation caused by formalin, carrageenan, and histamine, and on the model of proliferative inflammation accompanying cotton-pellet granuloma.
authors.affiliation: Laboratory of Phytopreparation Technology and Pharmacology, Institute of Phytochemistry, ul. Gazalieva 4, Karaganda, 470032 Kazakhstan.
authors.forename: A Zh
authors.initials: AZh
authors.lastname: Abil'daeva
authors.forename: R N
authors.initials: RN
authors.lastname: Pak
authors.forename: A T
authors.initials: AT
authors.lastname: Kulyiasov
authors.forename: S M
authors.initials: SM
authors.lastname: Adekenov
mesh_terms: D000208:Acute Disease; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use; D007249:Inflammation / Q000188:drug therapy / Q000209:etiology; D007783:Lactones / Q000627:therapeutic use*; D008297:Male; D051381:Rats; D012717:Sesquiterpenes / Q000627:therapeutic use*; D045789:Sesquiterpenes, Guaiane
chemical_list: C487619:11,13-dihydro-13-dimethylaminoarglabin hydrochloride; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000970:Antineoplastic Agents; D007783:Lactones; D012717:Sesquiterpenes; D045789:Sesquiterpenes, Guaiane; C083346:arglabin