title: Relative role of plutonium excretion with urine and feces from human body.
abstract: The ratio of plutonium content in 35 pairs of daily fecal and urine samples from 19 former MAYAK workers several decades after the end of occupational exposure was measured in clinical conditions. No dependence of the ratio Pu(feces)/Pu(urine) on plutonium aerosol transportability, sex, and age of workers was revealed in the late times after the end of occupational exposure. It was found that at the late times after the end of occupational exposure, the ratio of feces/urine is characterized by the lognormal distribution with the median value, 0.57, and error for this index characterized geometric deviation, sigmag = 1.12 Urinary and fecal excretions were analyzed after chronic exposure to inhaled plutonium compounds of different transportability for another group of 345 workers. During 500-16,000 d after the started chronic inhalation, plutonium biokinetic model ("Doses-2000") used in Southern Ural Biophysics Institute (SUBI) and based on the ICRP Publication 66 overestimated the feces/urine ratio by an order of magnitude as compared with the observed values. It indicates a necessity for further improvement of the biokinetic model used in SUBI.
authors.affiliation: Southern Ural Biophysics Institute, Federal Research Center of Biophysics, Ozyorskoe Shosse 19, Ozyorsk, Chelyabinsk Region, Russia, 456780. khohryakov@lab3.fib.ozersk.ru
authors.forename: V F
authors.initials: VF
authors.lastname: Khokhryakov
authors.forename: K G
authors.initials: KG
authors.lastname: Suslova
authors.forename: T I
authors.initials: TI
authors.lastname: Kudryavtseva
authors.forename: A E
authors.initials: AE
authors.lastname: Schadilov
authors.forename: V V
authors.initials: VV
authors.lastname: Vostrotin
authors.forename: N Yu
authors.initials: NY
authors.lastname: Lagounova
authors.forename: A Yu
authors.initials: AY
authors.lastname: Barabanshchikova
mesh_terms: D000280:Administration, Inhalation; D000368:Aged; D000369:Aged, 80 and over; D000396:Air Pollutants, Radioactive / Q000032:analysis / Q000493:pharmacokinetics / Q000652:urine; D001822:Body Burden; D005243:Feces / Q000737:chemistry*; D005260:Female; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate / Q000502:physiology; D008875:Middle Aged; D008954:Models, Biological; D009688:Nuclear Reactors; D016273:Occupational Exposure / Q000032:analysis*; D011005:Plutonium / Q000008:administration & dosage / Q000032:analysis / Q000493:pharmacokinetics* / Q000652:urine*; D011829:Radiation Dosage; D011835:Radiation Protection / Q000379:methods; D011874:Radiometry / Q000379:methods*; D012062:Relative Biological Effectiveness; D018570:Risk Assessment / Q000379:methods*; D012426:Russia
chemical_list: D000396:Air Pollutants, Radioactive; D011005:Plutonium