title: Resurgence in infectious syphilis in Ireland: an epidemiological study.
abstract: BACKGROUND
  In 2000, a syphilis outbreak was identified in Ireland.
  
  
  METHODS
  A prospective enhanced database was established in 2000. Crude incidence rates for the general population, men who have sex with men (MSM), and HIV-positive MSM were calculated.
  
  
  RESULTS
  Three hundred fifty-six cases of infectious syphilis were diagnosed at 1 center. Eighty-five percent of cases were identified as MSM. Crude incidence rates in MSM, ranging in age between 20 and 44 years, peaked in 2001 at 719 cases per 100000 of the MSM population. A total of 17.4% of cases occurred in HIV-infected individuals. Crude incidence rates of syphilis in HIV-positive MSM in the center increased to 7280 per 100000. Similar percentages of MSM with and without HIV infection had unprotected anal intercourse (37% and 41%, respectively).
  
  
  CONCLUSIONS
  High-risk sexual behavior continues among HIV-infected and -noninfected MSM. Crude incidence rates among MSM in Ireland are alarming when compared with other outbreaks.
authors.affiliation: St James's Hospital, Dublin, Ireland. hopkinss@tcd.ie
authors.forename: S
authors.initials: S
authors.lastname: Hopkins
authors.forename: F
authors.initials: F
authors.lastname: Lyons
authors.forename: C
authors.initials: C
authors.lastname: Coleman
authors.forename: G
authors.initials: G
authors.lastname: Courtney
authors.forename: C
authors.initials: C
authors.lastname: Bergin
authors.forename: F
authors.initials: F
authors.lastname: Mulcahy
mesh_terms: D000328:Adult; D017677:Age Distribution; D016208:Databases, Factual; D004196:Disease Outbreaks; D005260:Female; D015658:HIV Infections / Q000453:epidemiology; D018451:Homosexuality, Male / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D007494:Ireland / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D012725:Sexual Behavior / Q000706:statistics & numerical data; D013587:Syphilis / Q000453:epidemiology* / Q000209:etiology