title: [Serologic prevalence of HCV antibodies in health personnel in Peru].
abstract: In Peru, new cases of asymptomatic HCV infection are reported with certain frequency in patients with or without antecedents of blood transfusion. Although serologic screening has improved notoriously in the last years, there is still a population of polytransfused patients with high HCV risk (e.g. hemodialyzed patients), making up a major reservoir. Based on this premise, we decided to study the risk of the health worker population in Peru as another major HCV risk group. A total of 2,769 health workers from 7 Public Hospitals and 2 Private Hospitals in the City of Lima and from 7 Public Hospitals in 4 major/main cities of Peru (Chiclayo, Trujillo, Arequipa, and Cusco) were studied. All those workers, who due to their area of work had higher contact with blood and/or blood derivatives (Surgery, ICU, Traumatology, Gynecology, Gastroenterology, Hemodialysis and Laboratories-Blood Banks) were studied. The studied population accounts for 30% of the total health worker population in these services. All serums underwent the EIA-3 test (HCV-Cobas-Core, Lab. Roche, USA). The positive results were confirmed by RT-HCV (Ampiclor, Roche). The positive serums were confirmed by PCR and the positive results with high viral load underwent HCV genotyping (AMPICLOR-Roche Diagnostic, IGEN Diagnostic USA). Of the 2,769 health workers studied in Peru, 32 were positive for HCV antibodies (1.16% of the total number). Lima showed a prevalence slightly higher than the provinces: 26 out of 2,112 vs. 6 out of 657, or 1.23% vs. 0.91%, respectively. The higher risk is assumed by professional with higher level of contact with blood: 2 physicians (Hemodialysis), 5 nurses (HD) and Lab-Blood Bank technicians. The physicians and nurses share the same risk. If we segregate Lima from provinces, it can be seen that the highest risk is in Lima (1.34% compared to 1.07% in provinces). There is a major risk in health workers and the figures are slightly above those that were suspected for Peru (between 0.4 and 1.0). Finally, we can conclude that the group with the highest HCV risk among health workers is the group specialized in hemodialysis, followed by laboratory (1.79%), surgery (1.40%), and gastroenterology (0.8%). This is the first report at national level of HCV sero-prevalence in Peru.
authors.affiliation: APEH, and Clínicas Maison de Santé Lima-Perú, Lima, Peru.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Colichon Yerosh
authors.forename: Rolando
authors.initials: R
authors.lastname: Figueroa
authors.forename: Armando
authors.initials: A
authors.lastname: Moreno
authors.forename: Eduardo
authors.initials: E
authors.lastname: Zumaeta
authors.forename: Jorge
authors.initials: J
authors.lastname: Ferrandíz
authors.forename: Alejandro
authors.initials: A
authors.lastname: Busalleu
authors.forename: William
authors.initials: W
authors.lastname: Prado
authors.forename: Ricardo
authors.initials: R
authors.lastname: Candella
authors.forename: Alejandro
authors.initials: A
authors.lastname: Colichón
authors.forename: Wilson
authors.initials: W
authors.lastname: Rodriguez
authors.forename: Julio
authors.initials: J
authors.lastname: Espinoza
authors.forename: Wilfredo
authors.initials: W
authors.lastname: Kianman
authors.forename: Nelly
authors.initials: N
authors.lastname: Amaya
authors.forename: Segundo A
authors.initials: SA
authors.lastname: García Pérez
authors.forename: José
authors.initials: J
authors.lastname: Tello Rodriguez
authors.forename: Jesús
authors.initials: J
authors.lastname: Valdez
authors.forename: Héctor
authors.initials: H
authors.lastname: Paucar Sotomayor
authors.forename: César
authors.initials: C
authors.lastname: Sanchez
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002353:Carrier State; D005260:Female; D005762:Gastroenterology; D005838:Genotype; D006436:Hemodialysis Units, Hospital; D016174:Hepacivirus / Q000235:genetics; D006526:Hepatitis C / Q000453:epidemiology*; D018937:Hepatitis C Antibodies / Q000032:analysis; D006801:Humans; D007124:Immunoenzyme Techniques; D007753:Laboratories; D008297:Male; D008875:Middle Aged; D010564:Personnel, Hospital; D010568:Peru / Q000453:epidemiology; D016133:Polymerase Chain Reaction; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D013503:Surgery Department, Hospital
chemical_list: D018937:Hepatitis C Antibodies