title: Synthesis of benzo-fused lactams and lactones via Ru(II)-catalyzed cycloaddition of amide- and ester-tethered alpha,omega-diynes with terminal alkynes: electronic directing effect of internal conjugated carbonyl group.
abstract: In the presence of a catalytic amount of Cp*RuCl(cod), 1,6- and 1,7-diynes connected by an amide or an ester tether underwent cycloaddition with terminal alkynes at room temperature to give rise to cycloadducts in 40-93% yields with 63 : 37-83 : 17 regioisomer ratios.
authors.affiliation: Department of Applied Chemistry, Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University, Chikusa, Nagoya 464-8603, Japan. yamamoto@apchem.nagoya-u.ac.jp
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Keisuke
authors.initials: K
authors.lastname: Kinpara
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Saigoku
authors.forename: Hisao
authors.initials: H
authors.lastname: Nishiyama
authors.forename: Kenji
authors.initials: K
authors.lastname: Itoh