title: Frequency of Gram-negative bacterial pathogens in bloodstream infections and their resistance to antibiotics in the Czech Republic.
abstract: A study performed at 12 hospitals in the Czech Republic in 2001 evaluated the Gram-negative bacterial pathogens most frequently associated with bloodstream infections and their susceptibility to a selection of antimicrobial agents. Of 831 Gram-negative strains, the most frequently isolated organisms were Escherichia coli (32%), Klebsiella pneumoniae (24%) and Pseudomonas aeruginosa (10%). E. coli isolates were relatively susceptible to the antibiotics tested, whereas K. pneumoniae were relatively resistant to all agents except meropenem, and P. aeruginosa to all agents except gentamicin and amikacin. Other agents showed variable rates of resistance to penicillins, third-generation cephalosporins, aminoglycosides and ciprofloxacin.
authors.affiliation: Institute of Clinical Microbiology, Faculty Hospital, Hradec Králové, Czech Republic.
authors.forename: Pavel
authors.initials: P
authors.lastname: Cermák
authors.forename: Milan
authors.initials: M
authors.lastname: Kolár
authors.forename: Tomás
authors.initials: T
authors.lastname: Látal
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D016470:Bacteremia / Q000453:epidemiology* / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology; D018153:Czech Republic; D024881:Drug Resistance, Bacterial; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D016905:Gram-Negative Bacterial Infections / Q000453:epidemiology / Q000382:microbiology; D006761:Hospitals; D006801:Humans; D008826:Microbial Sensitivity Tests
chemical_list: D000900:Anti-Bacterial Agents