title: A mitogen-activated protein kinase that senses nitrogen regulates conidial germination and growth in Aspergillus fumigatus.
abstract: We show that the mitogen-activated protein (MAP) kinase pathway that responds to osmotic stress in Aspergillus fumigatus is also involved in nutritional sensing. This MAP kinase regulates conidial germination in response to the nitrogen source and is activated upon starvation for either carbon or nitrogen during vegetative growth.
authors.affiliation: Division of Pathology and Laboratory Medicine and Genes and Development Graduate Program, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
authors.forename: Tao
authors.initials: T
authors.lastname: Xue
authors.forename: C Kim
authors.initials: CK
authors.lastname: Nguyen
authors.forename: Angela
authors.initials: A
authors.lastname: Romans
authors.forename: Gregory S
authors.initials: GS
authors.lastname: May
mesh_terms: D001232:Aspergillus fumigatus / Q000201:enzymology* / Q000235:genetics / Q000254:growth & development*; D005656:Fungal Proteins / Q000235:genetics / Q000502:physiology*; D017353:Gene Deletion; D020935:MAP Kinase Signaling System; D020928:Mitogen-Activated Protein Kinases / Q000235:genetics / Q000502:physiology*; D009584:Nitrogen / Q000378:metabolism*
chemical_list: D005656:Fungal Proteins; D020928:Mitogen-Activated Protein Kinases; D009584:Nitrogen