Primary, extranodal, follicular non-Hodgkin lymphoma of the gallbladder: case report and a review of the literature.
We report the first case of isolated primary extranodal non-Hodgkin lymphoma follicular grade 2 limited to the gallbladder, found in the laparoscopic cholecystectomy specimen from a 70 year old woman with symptomatic cholelithiasis. The pericystic duct lymph node, surgical margins, and other lymph nodes, were not involved with lymphoma. According to the medical literature in English language, mucosa associated lymphoid tissue lymphoma (6 cases) is the most frequent type (38%) of primary gallbladder lymphomas (15 reported cases plus our case). Our case demonstrates that follicular lymphoma can be limited to the gallbladder, and confirm that it can occur in an organ normally devoid of lymphoid tissue.
Jelic
Tomislav M
TM
Department of Pathology, Charleston Area Medical Center, Memorial Hospital, 3200 MacCorkle Ave, Charleston, WV 25304, USA. tomislav.jelic@camc.org
Barreta
Telly M
TM
Yu
Min
M
Frame
James N
JN
Estallila
Oscar C
OC
Mellen
Paul F
PF
Newman
Samuel S
SS
Chang
Ho-Huang
HH
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005706:Gallbladder Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008198:Lymph Nodes / Q000473:pathology; D008224:Lymphoma, Follicular / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome