[The impact of uncorrected mitral insufficiency on left ventricle remodeling].
The aim of our study was to evaluate the influence of residual ischemic mitral insufficiency on patient's functional status and left ventricle remodeling after repair of ischemic mitral insufficiency.


METHODS
The study group consisted of 95 out of 128 patients who underwent mitral valve repair for ischemic mitral insufficiency at the Department of Cardiac Surgery of the Heart Center of Kaunas University of Medicine in 1996-2002. The study protocol included general clinical data, patients NYHA functional class, pre, peri and postoperative echocardiographic data.


RESULTS
In patients with residual MI (MR>or=2 grade) late postoperative left ventricle morphometric parameters, left ventricle ejection fraction and mean pulmonary artery pressure did not change. Size of left ventricle was reduced (left ventricle end diastolic diameter index decreased from 28.9+/-0.4 to 27.7+/-0.4 mm/m(2), p<0.001; left ventricle end systolic diameter index - from 22.2+/-0.6 to 19.7+/-0.7 mm/m(2), p<0.001), left ventricle ejection fraction increased (33.3+/-1.0 and 40.1+/-1.2%, p<0.0001), mean pulmonary artery pressure, NYHA functional class significantly decreased with MR<2 grade late postoperatively.


CONCLUSIONS
Residual MR is important factor for further worsening of patient's functional status and progressing of left ventricle remodeling after combined surgery.
Benetis
Rimantas
R
Clinic of Cardiosurgery, Kaunas University of Medicine, Eiveniu 2, 3007 Kaunas, Lithuania.
Jankauskiene
Loreta
L
Vaskelyte
Jolanta
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D003627:Data Interpretation, Statistical; D004452:Echocardiography; D015150:Echocardiography, Doppler; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000601:surgery*; D011651:Pulmonary Artery / Q000502:physiology; D013318:Stroke Volume; D013997:Time Factors; D016896:Treatment Outcome; D020257:Ventricular Remodeling