Complete resolution of pulmonary Rhizopus oryzae infection with itraconazole treatment: more evidence of the utility of azoles for zygomycosis.
Zygomycosis often requires aggressive surgical and antifungal therapy. We report a non-neutropenic patient with myelodysplastic syndrome and iron overload receiving cytotoxic therapy who presented with pulmonary Rhizopus oryzae infection. This patient was cured through the use of itraconazole alone and the literature on the utility of azole antifungals for zygomycosis is reviewed.
Eisen
D P
DP
Infectious Diseases Unit, Royal Brisbane Hospital, Herston, Queensland, Australia. damon.eisen@mh.org.au
Robson
J
J
D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001706:Biopsy; D006801:Humans; D017964:Itraconazole / Q000494:pharmacology / Q000627:therapeutic use*; D008168:Lung / Q000382:microbiology; D008172:Lung Diseases, Fungal / Q000150:complications / Q000188:drug therapy*; D008297:Male; D009190:Myelodysplastic Syndromes / Q000150:complications / Q000188:drug therapy; D012233:Rhizopus / Q000187:drug effects*; D013922:Thrombocytosis / Q000150:complications / Q000188:drug therapy; D020096:Zygomycosis / Q000150:complications / Q000188:drug therapy*
D000935:Antifungal Agents; D017964:Itraconazole