[Evaluation of Streptococcus pneumoniae urinary antigen test in healthy children with nasopharyngeal pneumococcal carriage].
We evaluated the influence of colonization with pneumococci on the results of Streptococcus pneumoniae urinary antigen detection assay by testing 23 healthy children aged 1-3 years in one nursery. Nasopharyngeal swab specimens for culture and urine samples for antigen detection test were obtained. 7 of 12 children who were nasopharyngeal carriers of pneumococci had a positive result of the urine antigen test. 3 of 11 children without pneumococci in the nasopharynx also had a positive result of the urine antigen test, who were diagnosed as having acute pneumonia within one month before this study. Thus we found that 58.3% of the children with pneumococcal carriage and 27.3% of non-carriers had false-positive test results. This test is not likely to be useful for diagnosing the etiology of childhood acute pneumococcal pneumonia.
Nariai
Akiyoshi
A
Department of Pediatrics, Yokohama Minami Kyosai Hospital.
Yokota
Shumpei
S
D000942:Antigens, Bacterial / Q000652:urine*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009305:Nasopharynx / Q000382:microbiology*; D013296:Streptococcus pneumoniae / Q000276:immunology* / Q000302:isolation & purification*
D000942:Antigens, Bacterial