Botulinum toxin in a case of hemimasticatory spasm with severe worsening during pregnancy.
Hemimasticatory spasm (HMS) is a rather uncommon movement disorder with a pathophysiology that is still unclear, although temporomasseter entrapment at the temporal fossa has been advanced. The authors present a case of HMS in a woman who experienced marked worsening in episode frequency and severity during pregnancy. Treatment with botulinum toxin led to marked improvement.
Cersósimo
María Graciela
MG
Movement Disorders and Parkinson's Disease Program, Institute of Applied Neurosciences, Hospital de Clínicas José de San Martín, Buenos Aires, Argentina.
Bertoti
Alicia
A
Roca
Claudia Uribe
CU
Micheli
Federico
F
D000328:Adult; D018726:Anti-Dyskinesia Agents / Q000627:therapeutic use*; D001905:Botulinum Toxins / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004576:Electromyography / Q000379:methods; D005260:Female; D019569:Hemifacial Spasm / Q000188:drug therapy*; D006801:Humans; D008410:Masticatory Muscles / Q000187:drug effects / Q000503:physiopathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*
D018726:Anti-Dyskinesia Agents; D001905:Botulinum Toxins