title: [Sequence polymorphisms of the mitochondrial DNA control region in 100 Chengdu Hans in China].
abstract: OBJECTIVE
  To study the genetic polymorphisms of the mitochondrial DNA (mtDNA) control region in Chengdu Han population.
  
  
  METHODS
  Sequence polymorphisms of the mtDNA control region, hypervariable regions I and II from 100 unrelated Chinese Hans were determined by PCR and direct sequencing.
  
  
  RESULTS
  Sequences of 404 nucleotides for hypervariable region I and 379 nucleotides for region II were obtained. Ninety-two and fifty variable sites were revealed in region I and region II respectively as compared to the reference sequence, and a total of 97 different genetic patterns from both the regions I and II were determined. The probability of identity was estimated at 1.84% for region I, 1.94% for region II, and 1.18% for both the regions.
  
  
  CONCLUSIONS
  These results suggest that sequence polymorphism of mtDNA control region would be very useful in forensic practice as a marker for individual identification.
authors.affiliation: College of Basic Medicine and Forensic Medicine, Sichuan University, Chengdu, Sichuan, 610041 PR China.
authors.forename: Wei-bo
authors.initials: WB
authors.lastname: Liang
authors.forename: Mei-li
authors.initials: ML
authors.lastname: Lu
authors.forename: Yi
authors.initials: Y
authors.lastname: Jia
authors.forename: Bin
authors.initials: B
authors.lastname: Zhou
authors.forename: Kuan-lin
authors.initials: KL
authors.lastname: Liu
authors.forename: Jing-hui
authors.initials: JH
authors.lastname: Chen
authors.forename: Miao
authors.initials: M
authors.lastname: Liao
authors.forename: Mei-yun
authors.initials: MY
authors.lastname: Wu
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
mesh_terms: D001483:Base Sequence; D002681:China; D004272:DNA, Mitochondrial / Q000737:chemistry*; D005828:Genetics, Population; D006801:Humans; D008969:Molecular Sequence Data; D009154:Mutation; D011110:Polymorphism, Genetic
chemical_list: D004272:DNA, Mitochondrial