Successful pregnancies in 2 infertile patients with endometrial adenocarcinoma.
Two infertile patients with well-differentiated endometrial adenocarcinoma succeeded in having their own babies with assisted reproductive technology following treatment with a high dose of medroxyprogesterone acetate and repeated endometrial curettages. Their follow-up pathological examinations revealed no evidence of recurrent disease. Consequently, conservative treatment may be indicated in patients with well-differentiated endometrial adenocarcinoma at an early stage who desire to preserve their fertility.
Nakao
Yoshifumi
Y
Department of Obstetrics and Gynecology, Faculty of Medicine, Saga University, Saga, Japan. nakaoy@cc.saga-u.ac.jp
Nomiyama
Mari
M
Kojima
Kayoko
K
Matsumoto
Yumi
Y
Yamasaki
Fumio
F
Iwasaka
Tsuyoshi
T
D000230:Adenocarcinoma / Q000473:pathology* / Q000628:therapy; D000328:Adult; D001707:Biopsy, Needle; D003131:Combined Modality Therapy; D004107:Dilatation and Curettage; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007247:Infertility, Female; D008423:Maternal Age; D017258:Medroxyprogesterone Acetate / Q000627:therapeutic use; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology* / Q000628:therapy*; D011256:Pregnancy Outcome; D027724:Reproductive Techniques, Assisted
D017258:Medroxyprogesterone Acetate