Effects of hypertonic dextran in hypovolaemic shock: a prospective clinical trial.
The aim of this paper is to report the results of prospective clinical trials of hypertonic saline dextran (HSD) in the resuscitation of hypovolaemic shock in critically injured patients. There are many types of fluids, which can be administered intravenously. Recent interest in the usage of HSD solution has confirmed that they have a place in resuscitation of a patient in shock. Heart rate and arterial pressure recovered well with HSD solution. The plasma osmolarity, sodium and potassium levels were significantly elevated in patients resuscitated with HSD. Urine output recovered rapidly and was well maintained throughout.
Alpar
Emin Kaya
EK
Department of Trauma and Orthopaedic Surgery, University Hospital Selly Oak NHS Trust, Raddlebarn Road, Birmingham B29 6JD, UK. alpar.med@btinternet.com
Killampalli
Vijay Vardhan
VV
D000328:Adult; D001794:Blood Pressure; D003911:Dextrans / Q000627:therapeutic use*; D005260:Female; D005440:Fluid Therapy / Q000379:methods*; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D011188:Potassium / Q000097:blood; D011446:Prospective Studies; D012462:Saline Solution, Hypertonic / Q000627:therapeutic use; D012769:Shock / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D012964:Sodium / Q000097:blood; D012965:Sodium Chloride / Q000627:therapeutic use*; D014947:Wounds and Injuries / Q000150:complications / Q000503:physiopathology / Q000628:therapy*
D003911:Dextrans; D012462:Saline Solution, Hypertonic; C104375:hypertonic saline-dextran solution; D012965:Sodium Chloride; D012964:Sodium; D011188:Potassium