Low prevalence of restless legs syndrome in patients with advanced chronic renal failure in the Indian population: a case controlled study.
BACKGROUND
Restless legs syndrome (RLS) is reported to occur in 20-70% of uremic patients. There is no study from India regarding the prevalence of RLS in chronic renal failure (CRF) patients. Studies from other Asian countries have shown a much lower prevalence compared to the West. This study investigated the prevalence of RLS in patients with advanced CRF in the Indian population.


METHODS
Sixty-five CRF patients and 99 controls were evaluated using a predesigned standard questionnaire. The control group consisted of prospective renal donors.


RESULTS
The mean age of our patients was 42.4 +/- 14.9 years as compared to 43.7 +/- 11.2 years (p = NS). The distribution of cause of CRF was as follows: diabetes 38.5%, hypertension 13.9%, chronic interstitial nephritis 29.2% and chronic glomerulonephritis 18.4%. RLS was present in 1 patient (1.5%) and none of the controls.


CONCLUSIONS
The prevalence of RLS in CRF patients in India is very low as compared to the Western population.
Bhowmik
Dipankar
D
Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India.
Bhatia
Manvir
M
Tiwari
Sumeet
S
Mahajan
Sandeep
S
Gupta
Sanjay
S
Agarwal
Sanjay K
SK
Dash
Suresh C
SC
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007194:India / Q000453:epidemiology; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012148:Restless Legs Syndrome / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D012720:Severity of Illness Index