Life threatening tongue angioedema associated with an angiotensin-converting enzyme inhibitor.
We present a case with angioedema of the tongue, following 1 dose of an angiotensin-converting enzyme (ACE) inhibitor ingestion. A gradual progression of angioedema required tracheotomy despite aggressive medical treatment and illustrates the severity of this adverse reaction. Although ACE inhibitors are considered safe, emergency physicians should be alert for minor angioedema at presentation that may progress to life threatening airway compromise.
Yanturali
Sedat
S
Dokuz Eylul University School of Medicine, Department of Pharmacology, Izmir, Turkey.
Ergun
Nurdan
N
Eminoglu
Ozlem
O
Kalkan
Sule
S
Tuncok
Yesim
Y
D000368:Aged; D000799:Angioedema / Q000139:chemically induced / Q000175:diagnosis* / Q000473:pathology; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D002216:Captopril / Q000009:adverse effects*; D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D004638:Emergency Treatment; D006801:Humans; D008297:Male; D014060:Tongue Diseases / Q000139:chemically induced / Q000175:diagnosis* / Q000473:pathology; D014140:Tracheotomy
D000806:Angiotensin-Converting Enzyme Inhibitors; D002216:Captopril