title: History of affective disorder and the experience of fatigue in rheumatoid arthritis.
abstract: OBJECTIVE
  To evaluate how a prior affective disorder (major depression or generalized anxiety disorder) affects current fatigue among individuals with rheumatoid arthritis (RA). To determine whether that relationship is mediated by self-efficacy expectations.
  
  
  METHODS
  Forty-eight RA patients with a prior affective disorder and 74 without a history of affective disorder completed a mailed questionnaire that included the Multidimensional Assessment of Fatigue and indicators of neuroticism and self efficacy.
  
  
  RESULTS
  RA patients with a history of affective disorder reported higher levels of fatigue than those with no previous affective disturbance. Controlling for neuroticism and self efficacy, affective disorder history continued to predict current fatigue. Mediational analyses revealed both direct and indirect effects (via self efficacy) of history of affective disorder on the experience of fatigue in RA.
  
  
  CONCLUSIONS
  History of affective disorder independently predicts higher levels of fatigue in RA patients, and self efficacy plays a mediating role in this relationship.
authors.affiliation: University of Florida, Gainesville, Florida, USA.
authors.forename: Rebecca L
authors.initials: RL
authors.lastname: Jump
authors.forename: Judith
authors.initials: J
authors.lastname: Fifield
authors.forename: Howard
authors.initials: H
authors.lastname: Tennen
authors.forename: Susan
authors.initials: S
authors.lastname: Reisine
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Giuliano
mesh_terms: D000368:Aged; D001007:Anxiety / Q000175:diagnosis / Q000523:psychology; D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000523:psychology*; D003863:Depression / Q000175:diagnosis / Q000523:psychology; D005221:Fatigue / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008487:Medical History Taking; D008875:Middle Aged; D008960:Models, Psychological; D019964:Mood Disorders / Q000175:diagnosis* / Q000523:psychology; D009497:Neurotic Disorders / Q000175:diagnosis / Q000523:psychology; D011237:Predictive Value of Tests; D020377:Self Efficacy; D011795:Surveys and Questionnaires