[Simultaneous isotachophoresis determination of dioxopromethazine and phenylephrine in eye drops].
Dioxopromethazine and phenylephrine were determined simultaneously in eye drops using the method of capillary isotachophoresis. Two electrolyte systems with different compositions and pH were examined. Prior to analysis, the eye drops are diluted with water in a ratio 1:50. Precision, correctness, linearity, robustness, and selectivity of the ITP method were evaluated for both electrolyte systems.
Kubacák
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P
Katedra farmaceutickej analýzy a nukleárnej farmácie Farmaceutickej fakulty Univerzity Komenského, Bratislava. kubacak@fpharm.uniba.sk
Valásková
I
I
Havránek
E
E
D004338:Drug Combinations; D019075:Electrophoresis, Capillary / Q000379:methods; D009883:Ophthalmic Solutions / Q000737:chemistry*; D010656:Phenylephrine / Q000032:analysis*; D011398:Promethazine / Q000031:analogs & derivatives* / Q000032:analysis*
D004338:Drug Combinations; D009883:Ophthalmic Solutions; D010656:Phenylephrine; C007508:dioxopromethazine; D011398:Promethazine