[Osteoporosis--fractures].
Bone fracture is the most serious outcome of osteoporosis. Main goal of treatment is fracture prevention. Clinical anti-fracture effect is higher than bone mineral density (BMD) increase. The previous fracture is bad prognostic sign. Good therapeutic outcomes are related to early diagnosis and treatment of osteoporosis before fracture is present. Therapeutic decision must be based on longterm risk and benefit ratio and keep in mind skeletal and desirable extraskeletal effects of drugs.
Babić-Naglić
Durdica
D
Klinika za reumatske bolesti i rehabilitaciju Medicinskoga fakulteta Sveucilista u Zagrebu Klinicki bolnicki centar Zagreb, Kispatićeva 12, 10000 Zagreb.
D005598:Fractures, Spontaneous / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D015663:Osteoporosis, Postmenopausal / Q000150:complications*