title: The urine protein heat coagulation test--a useful screening test for proteinuria in pregnancy in developing countries: a method validation study.
abstract: In many parts of the developing world, the urine protein heat coagulation test is routinely used to screen for proteinuria in pregnancy. The aim of this study was to determine whether > or =1+ on a standardised heat coagulation test reliably detects significant proteinuria and to compare it with the dipstick test for urinary protein. Heat coagulation test, dipstick test and 24-hour urine protein excretion results of 102 women were compared. > or =1+ on heat coagulation test is as sensitive and specific as > or =2+ on the dipstick test in detecting proteinuria of > or =500 mg/day. The heat coagulation test, however, is less sensitive than > or =1+ on dipstick in detecting lesser degrees of proteinuria.
authors.affiliation: Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka.
authors.forename: Vajira H W
authors.initials: VH
authors.lastname: Dissanayake
authors.forename: Linda
authors.initials: L
authors.lastname: Morgan
authors.forename: Fiona
authors.initials: F
authors.lastname: Broughton Pipkin
authors.forename: Veluppillai
authors.initials: V
authors.lastname: Vathanan
authors.forename: Samanthi
authors.initials: S
authors.lastname: Premaratne
authors.forename: Rohan W
authors.initials: RW
authors.lastname: Jayasekara
authors.forename: Harshalal R
authors.initials: HR
authors.lastname: Seneviratne
mesh_terms: D003906:Developing Countries; D005260:Female; D006358:Hot Temperature; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D011506:Proteins / Q000032:analysis*; D011507:Proteinuria / Q000175:diagnosis*; D011933:Reagent Kits, Diagnostic; D016482:Urinalysis / Q000379:methods* / Q000592:standards
chemical_list: D011506:Proteins; D011933:Reagent Kits, Diagnostic