Clinical responses of the corneal endothelium.
The corneal endothelium maintains corneal deturgescence and clarity by a pump-leak mechanism first described by David Maurice. This cell layer can be investigated clinically with specular microscopy, fluorophotometry, and pachymetry. We describe the clinical responses of the corneal endothelium to aging, drugs, glaucoma, contact lens wear, trauma, disease, and surgery.
Bourne
William M
WM
Mayo Clinic, Department of Ophthalmology, 200 First Street SW, Rochester, MN 55905, USA. bourne@mayo.edu
McLaren
Jay W
JW
D000375:Aging / Q000473:pathology; D003261:Contact Lenses; D003316:Corneal Diseases / Q000473:pathology; D004728:Endothelium, Corneal / Q000187:drug effects / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D015948:Keratoplasty, Penetrating