Adsorptive separation of beta-lactam antibiotics: technological perspectives.
An overview on adsorptive separation of cephalosporin antibiotics has been presented. The fundamental aspects on adsorption mechanism, kinetic and column dynamics have been exhaustedly discussed. The importance of molecular modelling studies on deducing implications for design of adsorbents has been highlighted. Finally, some aspects of process design and scale-up of adsorption column have been addressed and research needs of pragmatic importance have been identified.
Dutta
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M
Department of Chemistry, Indian Institute of Technology, Guwahati 781 039, India. monalisaikia@hotmail.com
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Dutta
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D000327:Adsorption; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification*; D001709:Biotechnology / Q000379:methods*; D002853:Chromatography, Liquid / Q000295:instrumentation / Q000379:methods*; D019544:Equipment Failure Analysis / Q000379:methods; D007700:Kinetics; D008956:Models, Chemical; D013678:Technology, Pharmaceutical / Q000379:methods*; D047090:beta-Lactams / Q000737:chemistry* / Q000302:isolation & purification*
D000900:Anti-Bacterial Agents; D047090:beta-Lactams