title: Ionized magnesium in gestational diabetes.
abstract: A longitudinal prospective study was performed in order to describe variations in ionized magnesium in patients with gestational diabetes. Twenty-two gestational diabetic women and 24 healthy pregnant women were included consecutively. Blood samples were obtained in the second and third trimester and 2 days postpartum in both groups. The blood samples were analysed for serum ionized magnesium, serum ionized calcium and pH. None of the groups demonstrated any time-related changes in ionized magnesium. However, in the third trimester the level of ionized magnesium was statistically significantly elevated in patients with gestational diabetes compared to controls (0.57 +/- 0.05 mmol/l vs. 0.51 +/- 0.06 mmol/l; p < 0.01). The level of ionized calcium remained stable throughout the study period in both groups. In conclusion our findings suggest that gestational diabetes is associated with elevated levels of ionized magnesium.
authors.affiliation: Department of Obstetrics and Gynecology, Glostrup University Hospital and Roskilde University Hospital, Denmark.
authors.forename: Pia
authors.initials: P
authors.lastname: Ertbeg
authors.forename: Pernille
authors.initials: P
authors.lastname: Nørgaard
authors.forename: Lisa
authors.initials: L
authors.lastname: Bang
authors.forename: Henrik
authors.initials: H
authors.lastname: Nyholm
authors.forename: Martin
authors.initials: M
authors.lastname: Rudnicki
mesh_terms: D002118:Calcium / Q000097:blood; D016640:Diabetes, Gestational / Q000097:blood*; D005260:Female; D005865:Gestational Age; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007477:Ions; D008137:Longitudinal Studies; D008274:Magnesium / Q000097:blood* / Q000737:chemistry; D011247:Pregnancy; D011446:Prospective Studies; D013997:Time Factors; D014471:Umbilical Veins / Q000378:metabolism
chemical_list: D007477:Ions; D008274:Magnesium; D002118:Calcium