title: Effects of extracorporeal shock waves on immature rabbit femurs.
abstract: We hypothesized that extracorporeal shock waves induce overgrowth and local increases in bone mineral content (BMC) in immature long bones. Immature male rabbits (n=14; 9 weeks old) were randomized equally between group I, which received 1000 100 MPa shock waves on the femoral shaft and group II, which received 5000. Unexposed femurs were used as controls. No fractures occurred in group I; three occurred in group II. Six weeks after exposure, the length and width were significantly larger (1.0 and 14.9%, respectively), and the BMC was significantly higher (22.8%) than those of control femurs in group I. These results of differences in width and BMC might be clinically useful.
authors.affiliation: Division of Orthopaedic Surgery, Chiba Children's Hospital, 579-1 Heta-chou, Midori-ku, Chiba 266-0007, Japan. h-saisu@dc4.so-net.ne.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Saisu
authors.forename: Kenji
authors.initials: K
authors.lastname: Takahashi
authors.forename: Makoto
authors.initials: M
authors.lastname: Kamegaya
authors.forename: Shigeru
authors.initials: S
authors.lastname: Mitsuhashi
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Wada
authors.forename: Hideshige
authors.initials: H
authors.lastname: Moriya
mesh_terms: D000818:Animals; D015519:Bone Density / Q000502:physiology; D005269:Femur / Q000502:physiology / Q000528:radiation effects*; D019220:High-Energy Shock Waves; D008297:Male; D023421:Models, Animal; D010012:Osteogenesis / Q000502:physiology; D010865:Pilot Projects; D011817:Rabbits; D011897:Random Allocation; D014465:Ultrasonics