title: Temporal bone pathology in hydrocephalus: changes in the inner ear due to increased intracranial pressure.
abstract: Changes in the inner ear due to increased intracranial pressure have not yet been clearly defined. We present a postmortem temporal bone study of child with hydrocephalus. The temporal bone was from a 2-year-old female with IVth ventricle ependymoblastoma. In the basal turn of the cochlea, degeneration of the organ of Corti and the nerve ganglion was observed. In the top and middle turn, structures were intact. The utricle and saccule were well preserved. We propose that changes in the inner ear due to increased intracranial pressure begin in the base of the cochlea, and extend to the apex in decreasing degree.
authors.affiliation: Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. gakutaikyo@yahoo.co.jp
authors.forename: Masaki
authors.initials: M
authors.lastname: Sano
authors.forename: Kimitaka
authors.initials: K
authors.lastname: Kaga
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Tsuzuku
authors.forename: Hideaki
authors.initials: H
authors.lastname: Sakata
mesh_terms: D001932:Brain Neoplasms / Q000150:complications; D002675:Child, Preschool; D002908:Chronic Disease; D007758:Ear, Inner / Q000473:pathology*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000473:pathology*; D018242:Neuroectodermal Tumors, Primitive / Q000150:complications; D013701:Temporal Bone / Q000473:pathology*