title: Growth and development of cellular slime mould Dictyostelium discoideum treated with DDT.
abstract: The effects of dichlorodiphenyl trichloroethane (DDT) on the growth, phagocytic activity, ultrastructure and developmental stages of a well known species of the cellular slime mould, Dictyostelium discoideum were studied. DDT, at doses of 60 ppm and above, inhibited growth of the vegetative cells and this was also evident from the colony blots which were smaller in size. A dose-dependent inhibition occurred in the phagocytic activity and macromolecular syntheses of DDT-treated cells. The cytomorphology of growing Dictyostelium cells, as revealed under light and electron microscopes, was profoundly affected by DDT treatment. Further, a considerable delay occurred in the various morphogenetic events in the slime mould cells exposed to DDT.
authors.affiliation: School of Life Sciences, Jawaharlal Nehru University, New Delhi - 110067, India.
authors.forename: R
authors.initials: R
authors.lastname: Gayatri
authors.forename: S
authors.initials: S
authors.lastname: Chatterjee