Betting on NKT and NK cells.
Natural killer T (NKT) cells, as their name implies, constitutively express markers and receptors first identified on bona fide natural killer (NK) cells, supporting a potential relationship between NKT and NK cells. In this issue of Immunity, Townsend et al. further define this relationship in terms of the transcription factor, T-bet.
Yokoyama
Wayne M
WM
Howard Hughes Medical Institute, Rheumatology Division Box 8045, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.
D000818:Animals; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D016131:Lymphocyte Subsets / Q000276:immunology*; D020825:T-Box Domain Proteins; D013601:T-Lymphocytes / Q000276:immunology*; D014157:Transcription Factors / Q000276:immunology*; D000098815:T-bet Transcription Factor
D020825:T-Box Domain Proteins; D000098815:T-bet Transcription Factor; D014157:Transcription Factors