Fine-needle aspiration cytology of pseudoangiomatous stromal hyperplasia of the breast.
Pseudoangiomatous stromal hyperplasia (PASH) is an uncommon lesion usually found in premenopausal women. Histologically, it is characterized by complex, anatomosing, empty slit-like spaces in a dense collagenous stroma. These pseudoangiomatous spaces are lined by monomorphic spindle cells of myofibroblastic differentiation. Cytological features of PASH are rarely discussed and reported, and may pose diagnostic challenge to surgical pathologists. Two cases of PASH are reported with emphasis on the FNAC features and cytologic differentiation from other benign fibroepithelial lesions.
Lui
Philip C W
PC
Department of Pathology, United Christian Hospital, Hong Kong, China.
Law
Bonita K B
BK
Chu
Winnie C W
WC
Pang
Lai-Man
LM
Tse
Gary M K
GM
D000328:Adult; D044963:Biopsy, Fine-Needle; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000175:diagnosis* / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006391:Hemangioma / Q000473:pathology*; D006801:Humans; D006965:Hyperplasia; D008875:Middle Aged