title: Using a beta-hairpin to mimic an alpha-helix: cyclic peptidomimetic inhibitors of the p53-HDM2 protein-protein interaction.
authors.affiliation: Institute of Organic Chemistry, University of Zürich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
authors.forename: Rudi
authors.initials: R
authors.lastname: Fasan
authors.forename: Ricardo L A
authors.initials: RL
authors.lastname: Dias
authors.forename: Kerstin
authors.initials: K
authors.lastname: Moehle
authors.forename: Oliver
authors.initials: O
authors.lastname: Zerbe
authors.forename: Jan W
authors.initials: JW
authors.lastname: Vrijbloed
authors.forename: Daniel
authors.initials: D
authors.lastname: Obrecht
authors.forename: John A
authors.initials: JA
authors.lastname: Robinson
mesh_terms: D000595:Amino Acid Sequence; D001665:Binding Sites; D032701:Biomimetics; D015374:Biosensing Techniques; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D018716:Molecular Mimicry; D008969:Molecular Sequence Data; D009687:Nuclear Proteins / Q000737:chemistry* / Q000378:metabolism; D010456:Peptides, Cyclic / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D011518:Proto-Oncogene Proteins / Q000737:chemistry* / Q000378:metabolism; D051736:Proto-Oncogene Proteins c-mdm2; D016159:Tumor Suppressor Protein p53 / Q000037:antagonists & inhibitors* / Q000737:chemistry* / Q000378:metabolism
chemical_list: D008024:Ligands; D009687:Nuclear Proteins; D010456:Peptides, Cyclic; D011518:Proto-Oncogene Proteins; D016159:Tumor Suppressor Protein p53; D051736:Proto-Oncogene Proteins c-mdm2