Experimental studies on ploidy evolution in yeast.
Variation in the prominence of haploidy and diploidy is a striking feature of eukaryote life cycles that has not been explained from an evolutionary point of view. the ease with which ploidy and other variables of population genetics may be manipulated in yeast make Saccharomyces cerevisiae an excellent subject for experiments on the fitness effects of ploidy. Several hypotheses have been advanced to explain the emphasis on diploidy in plants and animals, and yeast experiments have been particularly informative for a few. Evidence suggests that diploids may enjoy an immediate advantage over haploids in masking harmful mutations, avoiding the fitness cost such mutations impose on haploids. A convincing longer-term advantage for diploidy has proven elusive, and different evolutionary explanations for the origin and for the subsequent maintenance of diploidy may be required.
Zeyl
Clifford
C
Department of Biology, Wake Forest University, Winston-Salem, NC 27109, USA. zeylcw@wfu.edu
D004171:Diploidy; D019143:Evolution, Molecular; D005828:Genetics, Population; D006238:Haploidy; D012441:Saccharomyces cerevisiae / Q000235:genetics*