Disseminated linear calcinosis cutis associated with the Koebner phenomenon in an infant with congenital acute monocytic leukaemia.
We present a unique case of an infant with acute monocytic leukaemia who presented at birth with multiple rubbery, erythematous to violaceous subcutaneous nodules secondary to leukaemia cutis. As these infiltrates regressed with chemotherapy, numerous white to yellow linear confluent papules appeared in a scratch-like pattern. These lesions were widely disseminated but were concentrated across her face, trunk and extremities with relative sparing of the napkin area and back. We propose that these lesions represent a form of dystrophic calcinosis cutis that occurred secondary to koebnerization in an infant with congenital leukaemia cutis.
Satter
E K
EK
Department of Paediatric Dermatology, Children's Hospital/University of California San Diego, San Diego, CA, USA.
Maari
C H
CH
Morel
K D
KD
Eichenfield
L F
LF
Cunningham
B B
BB
Friedlander
S F
SF
Bergman
J N
JN
D002114:Calcinosis / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007938:Leukemia / Q000150:complications / Q000473:pathology*; D007948:Leukemia, Monocytic, Acute / Q000150:complications / Q000151:congenital*; D017254:Leukemic Infiltration / Q000150:complications / Q000473:pathology*; D012871:Skin Diseases / Q000150:complications / Q000473:pathology*