Intracellular xenobiotic concentration as a key factor of cytotoxicity: role of P-glycoprotein.
Simonova
V S
VS
Russian State Medical University, ul. Ostrovityanova 1, Moscow, 117997 Russia.
Samusenko
A V
AV
Polosukhina
E R
ER
Baryshnikov
A Yu
AY
Shtil
A A
AA
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000378:metabolism*; D001692:Biological Transport / Q000187:drug effects; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D002518:Ceramides / Q000378:metabolism / Q000633:toxicity; D006801:Humans; D042541:Intracellular Space / Q000378:metabolism*; D009848:Olivomycins / Q000378:metabolism / Q000633:toxicity; D015262:Xenobiotics / Q000378:metabolism / Q000633:toxicity*
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D002518:Ceramides; D015262:Xenobiotics; D009848:Olivomycins