Electron histochemical localization of cathepsin L in the liver.
The location of cathepsin L in rat liver was studied by electron histochemical methods. Enzyme activity was detected in lysosomes of hepatocytes, Kupffer cells, and endotheliocytes and extracellularly on hepatocyte microvilli.
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Laboratory of Morphology, Nikolae Testemitsyanu State University of Medicine and Pharmaceutics, Kishinev.
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D000818:Animals; D056668:Cathepsin L; D002403:Cathepsins / Q000032:analysis*; D003546:Cysteine Endopeptidases; D022781:Hepatocytes / Q000737:chemistry / Q000648:ultrastructure; D007728:Kupffer Cells / Q000737:chemistry / Q000648:ultrastructure; D008099:Liver / Q000201:enzymology* / Q000648:ultrastructure; D008247:Lysosomes / Q000737:chemistry / Q000648:ultrastructure; D008297:Male; D016253:Microscopy, Immunoelectron; D051381:Rats
D002403:Cathepsins; D003546:Cysteine Endopeptidases; D056668:Cathepsin L; C534280:Ctsl protein, rat