Factors influencing health-related quality of life of Asians with anxiety disorders in Singapore.
As little is known about health-related quality of life (HRQoL) in Asians with anxiety disorders, we assessed HRQoL in Singaporeans with anxiety disorders and identified factors influencing their HRQoL. Outpatients with anxiety disorders (n = 119) attending a hospital psychiatric clinic completed the Short Form 36 Health Survey (SF-36), Beck Anxiety Inventory (BAI) and General Health Questionnaire (GHQ-12). SF-36 score reduction from population norms (quantified as the number of standard deviations below the mean) in these subjects was compared with existing data on Singaporeans with various medical conditions and Americans with panic disorder (PD). Factors influencing HRQoL were examined using stepwise multiple linear regression models. SF-36 score reduction in these subjects (0.3-1.4 SD) was greater than that in Singaporeans with systemic lupus erythematosus or thyroid cancer survivors for seven scales but similar to that in Americans with PD (0.5-1.7 SD). BAI and GHQ-12 scores, presence of PD/generalized anxiety disorder, presence of chronic medical conditions, being married or increasing age accounted for 19-61% of the variance in six selected SF-36 scales. In conclusion, it can be said that Singaporeans with anxiety disorders experience clinically important reductions in HRQoL; both clinical and socio-demographic factors influence HRQoL in such subjects.
Luo
Nan
N
Department of Pharmacy, National University of Singapore, Singapore.
Fones
Calvin Soon-Leng
CS
Thumboo
Julian
J
Li
Shu-Chuen
SC
D000293:Adolescent; D000328:Adult; D000368:Aged; D001008:Anxiety Disorders / Q000175:diagnosis / Q000208:ethnology* / Q000523:psychology*; D044466:Asian People / Q000523:psychology*; D002681:China / Q000208:ethnology; D005260:Female; D006801:Humans; D007194:India / Q000208:ethnology; D016014:Linear Models; D008296:Malaysia / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D011594:Psychometrics; D011788:Quality of Life / Q000523:psychology; D012647:Self-Assessment; D018434:Sickness Impact Profile; D012846:Singapore