[Pancreatic tuberculosis: a rare cause of pseudoneoplastic obstructive jaundice].
Isolated pancreatic tuberculosis is rare, and can mimic pancreatic carcinoma. We report a case of pseudoneoplastic pancreatic tuberculosis revealed by an obstructive jaundice in a 35-Year-old man. Surgical pancreatic histopathology showed a caseating granulomatous inflammation and diagnosis was confirmed by detection of Mycobacterium tuberculosis DNA using specific polymerase chain reaction-based assay (PCR). The patient was successfully treated with quadruple antituberculous therapy. In the context of the diagnostic work-up of a hypodense pancreatic mass, the diagnosis of tuberculosis relies on the presence of pancreatic caseating granulomas, that can be obtained by endosonography-guided biopsy, thus avoiding laparotomy.
Beaulieu
Sandrine
S
Service d'Hépato-Gastroentérologie, Centre hospitalier intercommunal de Poissy/Saint Germain-en-Laye, Poissy. sbeaulieu@chi-poissy-st-germain.fr
Chouillard
Elie
E
Petit-Jean
Bruno
B
Vitte
René-Louis
RL
Eugene
Claude
C
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D004269:DNA, Bacterial / Q000032:analysis; D003937:Diagnosis, Differential; D006801:Humans; D041781:Jaundice, Obstructive / Q000209:etiology*; D008297:Male; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000472:pathogenicity; D010182:Pancreatic Diseases / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology*; D010190:Pancreatic Neoplasms / Q000175:diagnosis; D016133:Polymerase Chain Reaction; D014385:Tuberculosis, Gastrointestinal / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology*
D000995:Antitubercular Agents; D004269:DNA, Bacterial