title: Neurovirulence of four encephalitogenic dengue 3 virus strains isolated in Malaysia (1992-1994) is not attributed to their envelope protein.
abstract: The amino acid sequences of the envelope (E) protein of four encephalitogenic and five non-encephalitogenic dengue 3 virus strains isolated in Malaysia were determined and compared. Multiple sequence alignment revealed a high degree of similarity in the E protein of the strains suggesting that neurovirulence of these four encephalitogenic strains is not attributed to this protein.
authors.affiliation: Department of Parasitology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. fongmy@um.edu.my
authors.forename: Mun-Yik
authors.initials: MY
authors.lastname: Fong
authors.forename: Roziyah
authors.initials: R
authors.lastname: Yusup
authors.forename: Rohana
authors.initials: R
authors.lastname: Yusof
authors.forename: Sai-Kit
authors.initials: SK
authors.lastname: Lam
mesh_terms: D000595:Amino Acid Sequence; D003715:Dengue / Q000821:virology*; D003716:Dengue Virus / Q000145:classification / Q000472:pathogenicity*; D018792:Encephalitis, Viral / Q000821:virology*; D006801:Humans; D008969:Molecular Sequence Data; D014759:Viral Envelope Proteins / Q000235:genetics*; D014774:Virulence
chemical_list: D014759:Viral Envelope Proteins