The diagnosis of von Willebrand disease: a guideline from the UK Haemophilia Centre Doctors' Organization.
von Willebrand disease (VWD) is the commonest inherited bleeding disorder. However, despite an increasing understanding of the pathophysiology of VWD, the diagnosis of VWD is frequently difficult because of uncertainty regarding the relationship between laboratory assays and function in vivo. The objective of this guideline is to provide contemporary advice on a rational approach to the diagnosis of VWD. This is the second edition of this UK Haemophilia Centre Doctors' Organisation (UKHCDO) guideline and supersedes the previous edition which was published in 1997.
Laffan
M
M
Department of Haematology, Imperial College, Hammersmith Hospital, London, UK.
Brown
S A
SA
Collins
P W
PW
Cumming
A M
AM
Hill
F G H
FG
Keeling
D
D
Peake
I R
IR
Pasi
K J
KJ
D006403:Hematologic Tests / Q000379:methods*; D006801:Humans; D008487:Medical History Taking; D010808:Physical Examination; D014842:von Willebrand Diseases / Q000175:diagnosis*; D014841:von Willebrand Factor / Q000235:genetics / Q000378:metabolism
D014841:von Willebrand Factor