title: Treatment of chronic sialadenitis by intraductal penicillin or saline.
abstract: OBJECTIVE
  We sought to describe the treatment of chronic sialadenitis by intraductal penicillin or saline.
  
  
  METHODS
  The study group consisted of 32 males and 23 females with chronic submandibular sialadenitis aged 12 to 65 years and 16 males and 11 females with chronic parotitis aged 8 to 65 years who were treated by intraductal instillation of penicillin or saline.
  
  
  RESULTS
  In the patients with submandibular sialadenitis, 44 patients treated with penicillin and 11 treated with saline became symptom free; symptoms recurred in 3 treated with penicillin, of whom 2 became symptom free after further instillations and 1 after removal of a sialolith at the ductal orifice; and follow-up of 22 patients verified that 18 treated with penicillin and 4 with saline had been symptom free for 1 to 15 years and 1 to 3 years, respectively. In the patients with parotitis, 18 patients treated with penicillin, 8 treated with saline, and 1 treated with both became symptom free; symptoms recurred in 1 treated with penicillin and 1 with saline, both of whom became symptom free after further instillations; and follow-up of 15 patients verified that 11 treated with penicillin, 3 with saline, and 1 with both had been symptom free for 1 to 14 years, 2 to 12 years, and 3 years, respectively.
  
  
  CONCLUSIONS
  The intraductal instillation of penicillin or saline is a simple and surprisingly successful technique for the treatment of chronic sialadenitis.
authors.affiliation: Department of Oral Medicine and Oral Pathology, Dental School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Demetrios
authors.initials: D
authors.lastname: Antoniades
authors.forename: John D
authors.initials: JD
authors.lastname: Harrison
authors.forename: Apostolos
authors.initials: A
authors.lastname: Epivatianos
authors.forename: Panayotis
authors.initials: P
authors.lastname: Papanayotou
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D002404:Catheterization; D002648:Child; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010309:Parotitis / Q000188:drug therapy* / Q000209:etiology; D010400:Penicillin G / Q000008:administration & dosage*; D012465:Salivary Duct Calculi / Q000150:complications / Q000601:surgery; D018987:Salivary Ducts; D012793:Sialadenitis / Q000188:drug therapy* / Q000209:etiology; D012965:Sodium Chloride / Q000008:administration & dosage*; D013364:Submandibular Gland Diseases / Q000188:drug therapy* / Q000209:etiology
chemical_list: D000891:Anti-Infective Agents, Local; D012965:Sodium Chloride; D010400:Penicillin G