Catechol-based phosphoramidites: a new class of chiral ligands for rhodium-catalyzed asymmetric hydrogenations.
[reaction: see text] The synthesis and application of a new class of catechol-based phosphoramidites is described. Ees up to 99% were obtained in the rhodium-catalyzed asymmetric hydrogenation of dehydroamino acids and enamides.
Hoen
Rob
R
Department of Organic and Molecular Inorganic Chemistry, Stratingh Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
van den Berg
Michel
M
Bernsmann
Heiko
H
Minnaard
Adriaan J
AJ
de Vries
Johannes G
JG
Feringa
Ben L
BL