Periocular sarcoid in a horse.
A periocular nodular sarcoid of the right upper and lower eyelids was diagnosed in an 11-year-old Thoroughbred mare. Computed tomography scan revealed the extent of the tumor. The mass was surgically debulked under general anesthesia, and the affected periocular region was injected intralesionally with Bacillus of Calmette and Guerin (BCG). An emulsion of cell wall fractions was used, which has been modified to reduce the toxic and allergic effect, but retain the antitumor activity. In total, five injections were performed at 2-week intervals. At follow-up 7 months after the last BCG injection, the tumor was completely resolved. Two years after the last treatment, the horse remains tumor-free.
Komáromy
András M
AM
Department of Small and Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610-0126, USA. komaromy@vet.upenn.edu
Andrew
Stacy E
SE
Brooks
Dennis E
DE
Detrisac
Carol J
CJ
Gelatt
Kirk N
KN
D000818:Animals; D001500:BCG Vaccine / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005142:Eyelid Neoplasms / Q000175:diagnosis / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D006736:Horses; D015552:Injections, Intralesional / Q000662:veterinary; D012507:Sarcoidosis / Q000175:diagnosis / Q000662:veterinary*; D014057:Tomography, X-Ray Computed / Q000662:veterinary
D001500:BCG Vaccine