title: Primary esophageal lymphoma: a diagnostic challenge in acquired immunodeficiency syndrome--two case reports and review.
abstract: Although extranodal presentation occurs in the majority of cases of acquired immunodeficiency syndrome-associated non-Hodgkin lymphoma, the esophagus is only rarely affected. We discuss two patients with acquired immunodeficiency syndrome who presented with dysphagia and weight loss, who were found to have human immunodeficiency virus-associated primary esophageal lymphoma. Both patients died within a few weeks of diagnosis, reflecting the poor prognosis associated with this malignancy. Primary esophageal lymphoma should be considered in the differential diagnosis in a human immunodeficiency virus-seropositive patient presenting with dysphagia.
authors.affiliation: Department of Medicine, Division of Infectious Diseases, University of Texas Health Science Center at San Antonio, Mail Code 7881, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA. cnamalw@hotmail.com
authors.forename: C Namal
authors.initials: CN
authors.lastname: Weeratunge
authors.forename: Hector H
authors.initials: HH
authors.lastname: Bolivar
authors.forename: Gregory M
authors.initials: GM
authors.lastname: Anstead
authors.forename: Deedee H
authors.initials: DH
authors.lastname: Lu
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000821:virology; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000175:diagnosis* / Q000821:virology; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000821:virology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000821:virology; D008297:Male