The most profitable use of flow visualization in the elimination of thrombus from a monopivot magnetic suspension blood pump.
The purpose of this study was to eliminate fluid dynamic causes of thrombus formation for the monopivot magnetic suspension centrifugal pump under development with the aid of flow visualization as an indirect measurement tool for animal experiments. The formation of thrombus observed in early animal experiments was successfully overcome by combining the multiple washout holes at the center into a single hole, optimizing the hole diameter, and eliminating the pivot gap. Flow visualization was used to optimize the washout hole diameter influencing the flow around the pivot. In animal experiments flow visualization showed that the contours of thrombus corresponded to shear rates of 300 s(-1) or 1300-1700 s(-1). It was found that flow visualization is a useful technique to predict locations where low shear thrombi form and to optimize the pump design in the development stage.
Yamane
Takashi
T
National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan. yamane.t@aist.go.jp
Maruyama
Osamu
O
Nishida
Masahiro
M
Toyoda
Masahiro
M
Tsutsui
Tatsuo
T
Jikuya
Tomoaki
T
Shigeta
Osamu
O
Sankai
Yoshiyuki
Y
D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D002498:Centrifugation; D004867:Equipment Design; D006353:Heart-Assist Devices; D018056:Hemorheology / Q000379:methods*; D012756:Sheep; D013927:Thrombosis / Q000517:prevention & control*