title: Reduction of mitochondrial DNA content and respiratory chain activity occurs in adipocytes within 6-12 months of commencing nucleoside reverse transcriptase inhibitor therapy.
authors.forename: Emma
authors.initials: E
authors.lastname: Hammond
authors.forename: David
authors.initials: D
authors.lastname: Nolan
authors.forename: Ian
authors.initials: I
authors.lastname: James
authors.forename: Cecily
authors.initials: C
authors.lastname: Metcalf
authors.forename: Simon
authors.initials: S
authors.lastname: Mallal
mesh_terms: D017667:Adipocytes / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure*; D004272:DNA, Mitochondrial / Q000032:analysis* / Q000187:drug effects; D004579:Electron Transport; D003576:Electron Transport Complex IV / Q000378:metabolism; D015658:HIV Infections / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D015497:HIV-1; D006801:Humans; D018894:Reverse Transcriptase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D004272:DNA, Mitochondrial; D018894:Reverse Transcriptase Inhibitors; D003576:Electron Transport Complex IV