title: Biliary strictures are not the cause of pain in patients with chronic pancreatitis.
abstract: OBJECTIVE
  To investigate the relationship of strictures of the common bile duct (CBD) with pain in patients with chronic pancreatitis (CP) and jaundice.
  
  
  METHODS
  A total of 61 patients with CBD strictures caused by CP of alcoholic etiology were treated by endoscopic stent insertion for 1 year with scheduled stent exchanges. Pain was assessed using a visual analogue scale, and analgesic medication was recorded prior to and after endoscopic treatment.
  
  
  RESULTS
  Endoscopic drainage was successful in all cases, with complete resolution of jaundice during the 1-year follow-up period. Prior to the endoscopic stent insertion, pain scores were 6.8 +/- 6.3. Following stent therapy pain scores were 7.7 +/- 7.7. Pain scores, the number of patients requiring analgesics, the required amount of analgesics, and the type of analgesic medication did not change following treatment of CBD stricture.
  
  
  CONCLUSIONS
  Successful endoscopic drainage of biliary obstruction has no influence on pain pattern in patients with CP. CBD obstruction does not cause pain in patients with CP.
authors.affiliation: Department of Gastroenterology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Kahl
authors.forename: S
authors.initials: S
authors.lastname: Zimmermann
authors.forename: I
authors.initials: I
authors.lastname: Genz
authors.forename: U
authors.initials: U
authors.lastname: Schmidt
authors.forename: M
authors.initials: M
authors.lastname: Pross
authors.forename: H-U
authors.initials: HU
authors.lastname: Schulz
authors.forename: P
authors.initials: P
authors.lastname: Malfertheiner
mesh_terms: D015746:Abdominal Pain / Q000175:diagnosis / Q000209:etiology*; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D003137:Common Bile Duct Diseases / Q000150:complications* / Q000601:surgery; D003251:Constriction, Pathologic / Q000150:complications / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D041781:Jaundice, Obstructive / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000150:complications*; D015607:Stents / Q000009:adverse effects; D016896:Treatment Outcome