[The medical significance of interferons and their inducers].
The many-year use of interferons (IFN) and of their inducers in medical practice made the drugs a weighty component of a rational pharmacotherapy of infectious and oncological diseases. Their main advantage is a wide IFN efficiency spectrum preconditioned by their action mechanism and by the fact that IFNs are an important constituent element of the natural (congenital) immunity. The paper is a comprehensive survey of the antiviral IFN potentialities fit for the prevention and therapy of a huge variety of viral infections. Finally, it was proven that IFNs and some of their inducer are effective when used in the treatment of a number of autoimmune and allergic diseases.
Ershov
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D000276:Adjuvants, Immunologic / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use; D000998:Antiviral Agents / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D007369:Interferon Inducers / Q000494:pharmacology / Q000627:therapeutic use*; D007372:Interferons / Q000494:pharmacology / Q000502:physiology / Q000627:therapeutic use*
D000276:Adjuvants, Immunologic; D000970:Antineoplastic Agents; D000998:Antiviral Agents; D007369:Interferon Inducers; D007372:Interferons