title: Dieulafoy-like lesion of the colon presenting with massive lower gastrointestinal bleeding.
abstract: The Dieulafoys lesion is a rare cause of severe gastrointestinal hemorrhage. The lesion is usually located in the stomach, although it may occur anywhere in the gastrointestinal tract. It is characterized by severe bleeding from a minute submucosal arteriole that bleeds through a punctate erosion in an otherwise normal mucosa. We describe an elderly patient who presented with severe lower gastrointestinal bleeding caused by a colonic Dieulafoy-like lesion. This is the third report of colonic Dieulafoys lesion treated successfully with endoscopic hemoclipping. We review the pathophysiology, clinical presentation, diagnosis, and treatment of this rare disease.
authors.affiliation: Department of Endoscopy and Motility Unit, General Hospital George Gennimatas,, Ethnikis Aminis 41, TK 546 35, Thessaloniki, Greece. pantso@the.forthnet.gr
authors.forename: P
authors.initials: P
authors.lastname: Katsinelos
authors.forename: I
authors.initials: I
authors.lastname: Pilpilidis
authors.forename: G
authors.initials: G
authors.lastname: Paroutoglou
authors.forename: I
authors.initials: I
authors.lastname: Galanis
authors.forename: P
authors.initials: P
authors.lastname: Tsolkas
authors.forename: G
authors.initials: G
authors.lastname: Fotiadis
authors.forename: P
authors.initials: P
authors.lastname: Kapelidis
authors.forename: E
authors.initials: E
authors.lastname: Georgiadou
authors.forename: S
authors.initials: S
authors.lastname: Baltagiannis
authors.forename: S
authors.initials: S
authors.lastname: Dimiropoulos
authors.forename: E
authors.initials: E
authors.lastname: Kamperis
authors.forename: C
authors.initials: C
authors.lastname: Koutras
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001158:Arteries; D001803:Blood Transfusion; D012809:Colon, Sigmoid / Q000098:blood supply*; D003113:Colonoscopy; D003131:Combined Modality Therapy; D004837:Epinephrine / Q000627:therapeutic use; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy / Q000209:etiology* / Q000628:therapy; D016558:Hemostasis, Endoscopic / Q000379:methods*; D006489:Hemostatic Techniques / Q000295:instrumentation; D006801:Humans; D007413:Intestinal Mucosa / Q000098:blood supply*; D012422:Rupture, Spontaneous; D012810:Sigmoid Diseases / Q000150:complications / Q000628:therapy*; D013525:Surgical Instruments; D016896:Treatment Outcome; D014456:Ulcer / Q000150:complications / Q000628:therapy*; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
chemical_list: D014662:Vasoconstrictor Agents; D004837:Epinephrine