title: Clinical responses of the corneal endothelium.
abstract: The corneal endothelium maintains corneal deturgescence and clarity by a pump-leak mechanism first described by David Maurice. This cell layer can be investigated clinically with specular microscopy, fluorophotometry, and pachymetry. We describe the clinical responses of the corneal endothelium to aging, drugs, glaucoma, contact lens wear, trauma, disease, and surgery.
authors.affiliation: Mayo Clinic, Department of Ophthalmology, 200 First Street SW, Rochester, MN 55905, USA. bourne@mayo.edu
authors.forename: William M
authors.initials: WM
authors.lastname: Bourne
authors.forename: Jay W
authors.initials: JW
authors.lastname: McLaren
mesh_terms: D000375:Aging / Q000473:pathology; D003261:Contact Lenses; D003316:Corneal Diseases / Q000473:pathology; D004728:Endothelium, Corneal / Q000187:drug effects / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D015948:Keratoplasty, Penetrating