title: Choreic syndrome and coeliac disease: a hitherto unrecognised association.
abstract: Coeliac disease has been associated with a variety of neurological conditions, most frequently cerebellar ataxia and peripheral neuropathy. To date, chorea has not been associated with coeliac disease. We present the case histories of 4 individuals with coeliac disease and chorea (4 women, average age of onset of chorea 61 years). Unexpectedly, most of these patients showed a notable improvement in their motor symptoms after the introduction of a gluten-free diet.
authors.affiliation: Sobell Dept of Motor Neuroscience and Movement Disorders, Institute of Neurology, United Kingdom.
authors.forename: Anthony C
authors.initials: AC
authors.lastname: Pereira
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Edwards
authors.forename: Philip C
authors.initials: PC
authors.lastname: Buttery
authors.forename: Christopher H
authors.initials: CH
authors.lastname: Hawkes
authors.forename: Niall P
authors.initials: NP
authors.lastname: Quinn
authors.forename: Gavin
authors.initials: G
authors.lastname: Giovannoni
authors.forename: Marios
authors.initials: M
authors.lastname: Hadjivassiliou
authors.forename: Kailash P
authors.initials: KP
authors.lastname: Bhatia
mesh_terms: D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D002446:Celiac Disease / Q000150:complications* / Q000175:diagnosis* / Q000378:metabolism; D002819:Chorea / Q000150:complications* / Q000175:diagnosis* / Q000276:immunology; D003937:Diagnosis, Differential; D004569:Electroencephalography; D004576:Electromyography; D005260:Female; D005983:Glutens / Q000378:metabolism; D006683:HLA-DQ Antigens / Q000276:immunology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014057:Tomography, X-Ray Computed
chemical_list: D006683:HLA-DQ Antigens; D005983:Glutens