High-grade neuroendocrine carcinoma of the lung presenting an unusual spread mimicking pleural mesothelioma associated with dermatomyositis.
Neuroendocrine tumors of the lung comprise a heterogeneous group of tumors that represents a spectrum of disease from typical carcinoid tumors to the high-grade neuroendocrine carcinomas (large-cell neuroendocrine carcinomas and small-cell carcinomas). The high-grade neuroendocrine carcinomas are characterized by early metastasis and poor prognosis. The peripheral location and especially the massive pleural spread are rare for a high-grade neuroendocrine carcinoma. We report a case in which a high-grade neuroendocrine carcinoma, associated with dermatomyositis, presented an unusual pattern of progression, mimicking malignant pleural mesothelioma on diagnostic imaging.
Murakami
Yukiko
Y
Department of General Therapeutics, Kobe University Graduate School of Medicine, Kobe, Japan.
Kanazawa
Kenji
K
Okuno
Kaoru
K
Maekawa
Shuji
S
Matsuda
Yasuaki
Y
Miyamoto
Yoshitomo
Y
Nishimura
Yoshihiro
Y
Kanomata
Naoki
N
Ohbayashi
Chiho
C
Hashimoto
Masayoshi
M
Akita
Hozuka
H
D018278:Carcinoma, Neuroendocrine / Q000473:pathology*; D003882:Dermatomyositis / Q000473:pathology*; D003937:Diagnosis, Differential; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008654:Mesothelioma / Q000473:pathology*; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000473:pathology*