Determining the crystal structure of fibrinogen.
Summary. I have enjoyed reading previous historical sketches that have appeared in Journal of Thrombosis and Haemostasis, and especially those by Ted Tuddenham on factor VIII and Bjorn Dahlback on activated protein C resistance. Like those authors, I have tried to capture some of the excitement-as well as the disappointments-that occurred along the way to a long-term goal.
Doolittle
R F
RF
Center for Molecular Genetics, University of California, San Diego, La Jolla, CA 92093-0634, USA. rdoolittle@ucsd.edu
D000818:Animals; D003460:Crystallization; D018360:Crystallography, X-Ray / Q000266:history; D005340:Fibrinogen / Q000737:chemistry* / Q000266:history*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D011487:Protein Conformation
D005340:Fibrinogen