title: [Antibiotic sensitivity of Enterobacteriaceae isolated from women vagina and uterine cervix].
abstract: Based on performed investigation in the group of 200 women treated for recurrent and chronic vaginitis and cervicitis, the characteristic of isolated microorganism was done. There were found series of drug-resistant bacteria in the vagina and uterine cervical canal in women with recurrent vaginitis and chronic cervicitis. In 42.6% of patients with diagnosed chronic cervicitis (Cervicitis chronica n = 50) Escherichia coli strains were isolated, 5% of which produced extended spectrum beta-lactamases (ES beta L). In women with recurrent vaginitis (Colpitis recidivans n = 150) Escherichia coli strains where isolated in 45.6%. Among them 4.5% produced ES beta L. Expression of beta-lactamases with broadened substrate spectrum was done in double-disc-test.
  
  
  CONCLUSIONS
  1. Study of antibiotic sensitivity of isolated bacteria should be a diagnostic standard in bacterial infections of uterine cervix and vagina. 2. The choice of appropriate antibiotics should take into consideration the drug-resistance mechanisms of isolated bacteria. 3. When drug-resistant bacteria are isolated, combined therapy should be applied.
authors.affiliation: Katedra i Zakład Mikrobiologii i Immunologii Slaskiej Akademii Medycznej w Zabrzu.
authors.forename: Ilona
authors.initials: I
authors.lastname: Nolewajka-Lasak
authors.forename: Marek
authors.initials: M
authors.lastname: Rajca
authors.forename: Kazimierz
authors.initials: K
authors.lastname: Kamiński
authors.forename: Mariola
authors.initials: M
authors.lastname: Kunicka
authors.forename: Wojciech
authors.initials: W
authors.lastname: Król
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial; D004359:Drug Therapy, Combination / Q000494:pharmacology; D004755:Enterobacteriaceae / Q000187:drug effects* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D002575:Uterine Cervicitis / Q000188:drug therapy* / Q000382:microbiology; D016585:Vaginosis, Bacterial / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents