title: Ocular histopathologic observations in Norwegian Elkhounds with primary open-angle, closed-cleft glaucoma.
abstract: A retrospective histopathologic study of primary glaucoma in the Norwegian Elkhound was undertaken with the study of 9 clinically normal eyes and 22 glaucomatous eyes. All glaucomatous eyes showed goniodysgenesis as manifested by pectinate ligament dysplasia and/or trabecular meshwork dysplasia. Cystic degeneration of the iridociliary epithelial and/or peripheral retina was present in a high percentage of both normotensive and glaucomatous eyes. Utilizing the scheme proposed by Smith et al. (Veterinary and Comparative Ophthalmology 1993; 3: 16-28) the morphology of this disease in the Norwegian Elkhound would be classified as an open-angle, closed-cleft glaucoma, with histopathologic alterations of the outflow pathway similar to that described in other breeds with primary glaucoma.
authors.affiliation: Department of Ophthalmology, School of Medicine, University of North Carolina, Chapel Hill, NC 27599-7040, USA.
authors.forename: Yoshie
authors.initials: Y
authors.lastname: Oshima
authors.forename: Ellen
authors.initials: E
authors.lastname: Bjerkas
authors.forename: Robert L
authors.initials: RL
authors.lastname: Peiffer
mesh_terms: D000818:Animals; D016022:Case-Control Studies; D004283:Dog Diseases / Q000453:epidemiology* / Q000209:etiology; D004285:Dogs; D005260:Female; D005902:Glaucoma, Open-Angle / Q000453:epidemiology / Q000662:veterinary*; D008297:Male; D009664:Norway / Q000453:epidemiology; D010375:Pedigree; D011996:Records / Q000662:veterinary; D012189:Retrospective Studies