Hypercalcemia in a dog with resolution of iatrogenic Cushing's syndrome.
A six-year-old spayed Pug was presented with crust formation and ulcer on the skin. The patient had received long-term glucocorticoid therapy for treatment of tentatively diagnosed panniculitis. Severe calcification and pyoderma was observed and the patient was diagnosed with iatrogenic Cushing's syndrome and predonisolone was gradually withdrawn. After the withdrawal, the patient developed marked hypercalcemia (15.3 mg/dl) and finally died from renal failure. It is postulated that the eluted calcium from the calcified lesions may have contributed to the high serum calcium level as the underlying disease was not identified on necropsy.
Nakamura
Momoko
M
Department of Veterinary Internal Medicine, Tokyo University of Agriculture and Technology, Fachu, Japan.
Kawamura
Yuko
Y
Minegishi
Michiyo
M
Momoi
Yasuyuki
Y
Iwasaki
Toshiroh
T
D000818:Animals; D001774:Blood Chemical Analysis; D003480:Cushing Syndrome / Q000503:physiopathology / Q000662:veterinary*; D004283:Dog Diseases / Q000503:physiopathology*; D004285:Dogs; D017809:Fatal Outcome; D006652:Histological Techniques; D006934:Hypercalcemia / Q000503:physiopathology / Q000662:veterinary*; D007049:Iatrogenic Disease / Q000662:veterinary*; D011239:Prednisolone / Q000009:adverse effects
D011239:Prednisolone