title: PM-SCL autoantibody positive scleroderma with polymyositis (mechanic's hand: clinical aid in the diagnosis).
abstract: This report concerns a 56-year-old-woman presenting PM-SCL autoantibody positive scleroderma with dermatomyositis (scleromyositis) and concomitant interstitial lung fibrosis. The recently observed overlapping syndrome is characterized by the presence of specific autoantibodies, HLA-type association and benign course. A new skin symptom ("mechanic's hands") predicts the disease, in particular the interstitial lung pathology, which is its most relevant internal manifestation.
authors.affiliation: Department of Dermatology, County Hospital of Bács-Kiskun (Kecskemét), 6000 Kecskemét, Nagykörösi u 15, Hungary. laszlo.a.torok@matavnet.hu
authors.forename: L
authors.initials: L
authors.lastname: Török
authors.forename: K
authors.initials: K
authors.lastname: Dankó
authors.forename: G
authors.initials: G
authors.lastname: Cserni
authors.forename: G
authors.initials: G
authors.lastname: Szûcs
mesh_terms: D001323:Autoantibodies / Q000276:immunology; D001707:Biopsy, Needle; D003882:Dermatomyositis / Q000150:complications / Q000276:immunology* / Q000473:pathology; D004485:Eczema / Q000150:complications / Q000276:immunology* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006229:Hand Dermatoses / Q000150:complications / Q000276:immunology / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D017563:Lung Diseases, Interstitial / Q000150:complications / Q000276:immunology* / Q000473:pathology*; D008875:Middle Aged; D018570:Risk Assessment; D012594:Scleroderma, Localized / Q000150:complications / Q000276:immunology* / Q000473:pathology; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed
chemical_list: D001323:Autoantibodies