Autologous cord blood transfusion in an infant with a huge sacrococcygeal teratoma.
We describe a case of cord blood harvest for autologous transfusion in a neonate weighing 3,992 g with a giant sacrococcygeal teratoma. The umbilical vein was pierced with an 18-gauge needle, and placental blood was withdrawn into two 50-ml syringes filled with 4 ml of citrate-phosphate-dextrose solution. Resection of the sacrococcygeal teratoma was performed on day one. During the operation the infant lost 46 ml of whole blood, more than 15% of the estimated total blood volume, and thus underwent autologous transfusion with 27.8 ml of packed red cells obtained from autologous cord blood. Consequently, she could avoid homologous blood transfusion during the hospital stay. This case highlights the safety of this procedure, with no evidence of consumption coagulopathy, hemolysis or bacterial infection.
Hosono
Shigeharu
S
Department of Pediatrics, Nihon University School of Medicine, Tokyo, Japan. hosonos@med.nihon-u.ac.jp
Mugishima
Hideo
H
Nakano
Yuko
Y
Murabayashi
Masao
M
Shimada
Masami
M
Minato
Michiyoshi
M
Takahashi
Shigeru
S
Harada
Kensuke
K
Ikeda
Taro
T
Fukuzawa
Masahiro
M
D016063:Blood Loss, Surgical; D001800:Blood Specimen Collection; D001804:Blood Transfusion, Autologous; D005260:Female; D005312:Fetal Blood / Q000637:transplantation*; D006801:Humans; D007231:Infant, Newborn; D012445:Sacrococcygeal Region; D013125:Spinal Neoplasms / Q000601:surgery*; D013724:Teratoma / Q000601:surgery*