title: [Neuroendocrine "silent" tumors of the pancreas].
abstract: Neuroendocrine tumors are the rare pathology. They are characterized by slow growth and favorable prognosis for life. From 1985 to 2000 fifty-two patients with "silent" neuroendocrine tumors were treated. Clinical symptoms in 60% patients were associated with squeezing of the surrounding organs and tissues (gastroduodenal obstruction or cholestasis), in 20% patients tumors were diagnosed within the framework of syndrome of multiple endocrine metaplasia and in 16% cases tumors were revealed accidentally. Fifty-two percent of the tumors located in the head of the pancreas, 23 and 25% - in the corpus and tail of the pancreas respectively. All the patients underwent surgery. Neuroendocrine nature of the tumors was verified during morphologic study. Five-year survival was 51.8, 41.6 and 54.5% when tumor located in the head, corpus and tail of the pancreas, respectively.
authors.affiliation: Institut khirurgii im. A. V. Vishnevskogo RAMN, MONIKI im. M. F. Vladimirskogo.
authors.forename: V A
authors.initials: VA
authors.lastname: Kubyshkin
authors.forename: I M
authors.initials: IM
authors.lastname: Buriev
authors.forename: Z A
authors.initials: ZA
authors.lastname: Abdulkerimov
authors.forename: L E
authors.initials: LE
authors.lastname: Gurevich
authors.forename: A V
authors.initials: AV
authors.lastname: Kochatkov
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D018358:Neuroendocrine Tumors / Q000145:classification* / Q000473:pathology* / Q000601:surgery; D010146:Pain / Q000453:epidemiology; D010190:Pancreatic Neoplasms / Q000145:classification* / Q000473:pathology* / Q000601:surgery; D011183:Postoperative Complications / Q000453:epidemiology