Physiological methods to measure motor function in humans and animals with spinal cord injury.
This article compares some physiological methods commonly used to measure the functional capability of the motor system in humans and animals after spinal cord injury. Some of the differences between animal and human experimentation are considered first. Then we discuss how to measure the effectiveness of conduction through the motor system. We describe ways to assess the integration of different inputs at the spinal cord and to measure the responsiveness of the neuromuscular system. We conclude that comparisons across species are invaluable to understand the control of movement, both before and after injury.
Thomas
Christine K
CK
The Miami Project to Cure Paralysis, Department of Neurological Surgery, University of Miami School of Medicine, Miami, FL 33136, USA. cthomas@miami.edu
Noga
Brian R
BR
D000818:Animals; D004195:Disease Models, Animal; D004576:Electromyography; D006801:Humans; D008124:Locomotion / Q000502:physiology; D023421:Models, Animal; D009119:Muscle Contraction / Q000502:physiology; D020127:Recovery of Function / Q000502:physiology*; D012018:Reflex / Q000502:physiology; D013116:Spinal Cord / Q000503:physiopathology; D013119:Spinal Cord Injuries / Q000503:physiopathology* / Q000534:rehabilitation*