[Prognosis significance of the TNM clinic stage for five year survival time in primary carcinoma of the gallbladder].
OBJECTIVE
To determine the prognosis significance of the TNM clinic stage and the five-year survival rate of patients with primary carcinoma of the gallbladder.


METHODS
A descriptive, longitudinal, observational study with a single-box empirical design that evaluated 71 patients with gallbladder cancer who had surgical resection of the neoplasia in the Belén Hospital in Trujillo, Peru between 1966 and 2000.


RESULTS
The mean age of the total series was 61.6+/-12.04 years (ranging from 33 to 88 years). Most of the patients belonged to the age group of 60 years or older (56.3%). Ten patients were males (14.1%) and 61 were females (85.9%), with a M:F ratio of 1:6.1. In the univariate analysis using the log-rank test, the following variables were significantly related to a five-year survival time: primary tumor (p=0.0001), regional ganglionic condition (p=0.0038), clinic stage (p=0.00001). The actuarial survival rate of all the series at 12, 36, and 60 months was 30%, 14.1%, and 11.3%, respectively.


CONCLUSIONS
The prognosis factors significantly related to five-year survival were: primary tumor (p=0.0001), regional ganglionic condition (p=0.0038) and clinic stage (p=0.00001). The actuarial survival rate of all the series at 12, 36, and 60 months was 30%, 14.1%, and 11.3%, respectively.
Arbayza-Avalos
Yessenia Katherin
YK
Departamento de Cirugía del Hospital Belén de Trujillo and Curso de Cirurgía I, Univeridad Privada Antenor Orrego.
Díaz-Plasencia
Juan Alberto
JA
Segura-Plasencia
Niler Manuel
NM
Yan-Quiroz
Edgar Fermín
EF
D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003627:Data Interpretation, Statistical; D005260:Female; D005704:Gallbladder / Q000473:pathology; D005706:Gallbladder Neoplasms / Q000401:mortality* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008137:Longitudinal Studies; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D016019:Survival Analysis; D013997:Time Factors