title: Synthesis of (2S,3R)-[3',3',3'-2H3]-valine and (2S,3S)-4-fluorovaline.
abstract: A new synthesis of (2S,3R)-[3',3',3'-2H3]-valine has been completed and (2S,3S)-4-fluorovaline has been synthesised for the first time. Both compounds have been prepared by routes involving stereoselective addition to the (S)-pyroglutamate derivative and are available for studies in several areas of bio-organic chemistry.
authors.affiliation: Sussex Centre for Biomolecular Design and Drug Discovery, Department of Chemistry, University of Sussex, Falmer, Brighton, UK BN1 9QJ.
authors.forename: Jean-Damien
authors.initials: JD
authors.lastname: Charrier
authors.forename: Peter B
authors.initials: PB
authors.lastname: Hitchcock
authors.forename: Douglas W
authors.initials: DW
authors.lastname: Young