title: A trial of omega-3 fatty acids for prevention of hypertension.
abstract: Although omega-3 polyunsaturated fatty acid supplements reduce blood pressure (BP), the typical doses cause untoward side effects. A novel fatty acid supplement was tested in a randomized trial of patients with high normal diastolic BP. The novel fatty acid supplement did not significantly reduce BP in patients with high normal diastolic blood pressure.
authors.affiliation: Duke Clinical Research Institute, Durham, North Carolina, USA. dokholyan@duke.edu
authors.forename: Rachel S
authors.initials: RS
authors.lastname: Dokholyan
authors.forename: Christine M
authors.initials: CM
authors.lastname: Albert
authors.forename: Lawrence J
authors.initials: LJ
authors.lastname: Appel
authors.forename: Nancy R
authors.initials: NR
authors.lastname: Cook
authors.forename: Paul
authors.initials: P
authors.lastname: Whelton
authors.forename: Charles H
authors.initials: CH
authors.lastname: Hennekens
mesh_terms: D001794:Blood Pressure / Q000187:drug effects; D002214:Capsules; D004338:Drug Combinations; D015118:Eicosapentaenoic Acid / Q000008:administration & dosage* / Q000494:pharmacology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D017965:gamma-Linolenic Acid / Q000008:administration & dosage* / Q000494:pharmacology
chemical_list: D002214:Capsules; D004338:Drug Combinations; D017965:gamma-Linolenic Acid; D015118:Eicosapentaenoic Acid