title: Contact lens, hyperopia and endothelial changes. A case report.
abstract: BACKGROUND
  We report on a 62-year-old healthy woman who suffered from bilateral predescemetic opacities, where the underlying disorder could not be identified. She had bilateral keratopathy with corneal edema, a diffuse predescemetic avascular haze and deszemetic folds. Because of high hyperopia (right +7.50/left +7.75) she weared soft contact lenses for years.
  
  
  METHODS
  Removal of contact lenses. Treatment with local steroids and tear substitutes.
  
  
  RESULTS
  One year after cessation of contact lenses VA recovered from RE 0.3/LE 0.1 to 0.8/0.63, the deep stromal opacity cleared up, the corneal edema recessed slightly.
  
  
  CONCLUSIONS
  The differential diagnosis concludes either a pure contact lens change that is not completely reversible or a possible posterior polymorphous dystrophy that worsens with long-term contact lens wear and improves on cessation.
authors.affiliation: University of Cologne, Center of Ophthalmology, Köln, Germany. sigrid.roters@medizin.uni-koeln.de
authors.forename: Sigrid
authors.initials: S
authors.lastname: Roters
authors.forename: Maria
authors.initials: M
authors.lastname: Severin
authors.forename: Walter
authors.initials: W
authors.lastname: Konen
authors.forename: Peter
authors.initials: P
authors.lastname: Szurman
authors.forename: Dietrich
authors.initials: D
authors.lastname: von Domarus
authors.forename: Günter K
authors.initials: GK
authors.lastname: Krieglstein
mesh_terms: D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects*; D003316:Corneal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D004359:Drug Therapy, Combination; D004728:Endothelium, Corneal / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D006956:Hyperopia / Q000628:therapy*; D008875:Middle Aged; D009883:Ophthalmic Solutions / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D014792:Visual Acuity
chemical_list: D005938:Glucocorticoids; D009883:Ophthalmic Solutions; D011239:Prednisolone