Calciphylaxis associated with acute, reversible renal failure in the setting of alcoholic cirrhosis.
We describe a case of calciphylaxis in a 47-year-old man with alcohol-induced end-stage liver disease and acute renal failure secondary to hepatorenal syndrome. Possible contributing factors included transiently impaired renal function, protein C and S deficiencies, elevated calcium-phosphate product, hyperphosphatemia, low serum albumin, repeated albumin infusions, and elevated alkaline phosphatase level.
Chavel
Severine M
SM
Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520-8059, USA.
Taraszka
Karen S
KS
Schaffer
Julie V
JV
Lazova
Rossitza
R
Schechner
Jeffrey S
JS
D058186:Acute Kidney Injury / Q000209:etiology*; D001706:Biopsy; D002115:Calciphylaxis / Q000175:diagnosis / Q000209:etiology*; D006530:Hepatorenal Syndrome / Q000150:complications*; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000175:diagnosis / Q000209:etiology*