Application of human leukocyte antigen matching in the allocation of kidneys from cadaveric organ donors in the Nordic countries.
The Nordic organ exchange organization Scandiatransplant was founded in 1969. It covers a population of 24.41 million inhabitants in five countries: Denmark (5.45 million), Finland (5.19 million), Iceland (0.29 million), Norway (4.54 million), and Sweden (8.94 million). Initially, the purpose of Scandiatransplant was to establish and maintain a common waiting list for all Nordic patients with end-stage renal failure waiting for a cadaveric kidney transplant. The basis of maintaining a common Nordic waiting list was the recognition of the wide polymorphism of the human leukocyte antigen system, which demands a substantial pool of waiting patients to provide optimal histocompatibility matching between organ donor and recipient. Thus, one of the major tasks of the organization was and still is to specify rules for the exchange of kidneys between the participating transplant centers. Scandiatransplant includes the cooperation of all 10 Nordic kidney transplant centers in addition to eight immunology laboratories. Denmark has four transplant centers located in Copenhagen, Herlev, Odense, and Aarhus. Finland has one center in Helsinki. Norway has one center located in Oslo. Sweden has four kidney transplantation centers located in each of the university hospitals in Göteborg, Malmö, Stockholm, and Uppsala. The fifth Nordic country, Iceland, is participating fully in organ donation but has no individual transplant center. Organ transplantation in Icelandic patients is performed in other Nordic countries.
Madsen
Melvin
M
Scandiatransplant, Department of Clinical Immunology, Aarhus University Hospital, Skejby Sygehus, Denmark.
Asmundsson
Páll
P
Bentdal
Øystein H
ØH
Friman
Styrbjörn
S
Persson
Nils H
NH
Salmela
Kaija
K
Grunnet
Niels
N
D002102:Cadaver; D006650:Histocompatibility Testing; D006801:Humans; D007668:Kidney; D016030:Kidney Transplantation; D040841:Resource Allocation; D012537:Scandinavian and Nordic Countries; D014019:Tissue Donors