title: Neonatal gastric perforation.
abstract: BACKGROUND
  Gastric perforation in neonates is a catastrophe associated with high morbidity. Most are due to underlying primary pathology.
  
  
  OBJECTIVE
  To review the management of gastric perforation in neonates in Kwa Zulu-Natal, South Africa.
  
  
  METHODS
  Retrospective study of consecutive complete data sets of neonates presenting with gastric perforation.
  
  
  METHODS
  Department of Paediatric Surgery, Nelson R. Mandela School of Medicine, University of Natal, Durban, South Africa.
  
  
  METHODS
  Eight neonates treated for gastric perforation between January 1998 and April 2003.
  
  
  METHODS
  Morbidity and mortality.
  
  
  RESULTS
  There was an equal number of males and females. Median birth weight was 2.0 kg with a range of 1.4 to 3.2 kg. Five of the eight neonates were premature. Primary pathologies were associated with perforation in seven of the eight neonates. Prematurity, low birth weight and pneumonia were contributing factors to the poor outcome. Sepsis was a complication in seven of the eight neonates leading to their death (88% mortality).
  
  
  CONCLUSIONS
  Active perinatal management, early treatment of primary pathologies, and protection of the stomach against distension in neonates at risk are essential in the management of neonatal gastric perforation.
authors.affiliation: Department of Surgery, Faculty of Health Sciences, Moi University, Eldoret, Kenya.
authors.forename: R T
authors.initials: RT
authors.lastname: Kuremu
authors.forename: G P
authors.initials: GP
authors.lastname: Hadley
authors.forename: R
authors.initials: R
authors.lastname: Wiersma
mesh_terms: D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D012422:Rupture, Spontaneous / Q000209:etiology / Q000601:surgery; D013019:South Africa; D013270:Stomach / Q000473:pathology* / Q000601:surgery*