Cerebral infarction as a complication of nephrotic syndrome: a case report with a review of the literature.
Arterial thrombosis is relatively rare compared with venous thrombosis in nephrotic syndrome. However, the assessment of its pathogenesis and risk factors in individual patient with nephrotic syndrome is necessary to allow appropriate prophylactic management because it is a potentially serious problem. Hereby, with review of the literature, we report a case of a 53 yr-old man with cerebral infarction associated with nephrotic syndrome due to focal segmental glomerulosclerosis during the course of treatments with diuretics and steroid. It reveals that the hypercoagulable state in nephrotic syndrome can be associated with cerebral infarction in adults. Prophylactic anticoagulants can be considered to reduce the risk of serious cerebral infarction in nephrotic patients with risk factors such as severe hypoalbuminemia and on diuretics or steroid treatment, even in young patients regardless of types of underlying glomerular diseases.
Yun
Yeo Wook
YW
Department of Internal Medicine, Hanyang University, Seoul, Korea.
Chung
Sungjin
S
You
Sun-Jin
SJ
Lee
Dong Kyu
DK
Lee
Kyu-Yong
KY
Han
Sang-Woong
SW
Jee
Heng Ok
HO
Kim
Ho-Jung
HJ
D002544:Cerebral Infarction / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000150:complications* / Q000453:epidemiology; D012307:Risk Factors