Perinatal pathology in the context of a clinical trial: a review of the literature.
Perinatal postmortem rates are declining world wide. In the United Kingdom, perinatal pathology has recently been seriously undermined by controversy. There are important consequences for perinatal trials that include pathology studies. This review looks at the reasons for the decline in perinatal postmortem examinations and the effects on research.
Snowdon
C
C
Medical Statistics Unit, London School of Hygiene and Tropical Medicine, University of London, Keppel Street, London WC1E 7HT, UK. cms1000@cam.ac.uk
Elbourne
D R
DR
Garcia
J
J
D001290:Attitude; D001291:Attitude of Health Personnel; D001344:Autopsy; D002423:Cause of Death; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000401:mortality / Q000473:pathology*; D010290:Parents; D010338:Pathology, Clinical / Q000379:methods*; D020458:Third-Party Consent; D006113:United Kingdom