title: Hypercalcemia in a dog with resolution of iatrogenic Cushing's syndrome.
abstract: A six-year-old spayed Pug was presented with crust formation and ulcer on the skin. The patient had received long-term glucocorticoid therapy for treatment of tentatively diagnosed panniculitis. Severe calcification and pyoderma was observed and the patient was diagnosed with iatrogenic Cushing's syndrome and predonisolone was gradually withdrawn. After the withdrawal, the patient developed marked hypercalcemia (15.3 mg/dl) and finally died from renal failure. It is postulated that the eluted calcium from the calcified lesions may have contributed to the high serum calcium level as the underlying disease was not identified on necropsy.
authors.affiliation: Department of Veterinary Internal Medicine, Tokyo University of Agriculture and Technology, Fachu, Japan.
authors.forename: Momoko
authors.initials: M
authors.lastname: Nakamura
authors.forename: Yuko
authors.initials: Y
authors.lastname: Kawamura
authors.forename: Michiyo
authors.initials: M
authors.lastname: Minegishi
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Momoi
authors.forename: Toshiroh
authors.initials: T
authors.lastname: Iwasaki
mesh_terms: D000818:Animals; D001774:Blood Chemical Analysis; D003480:Cushing Syndrome / Q000503:physiopathology / Q000662:veterinary*; D004283:Dog Diseases / Q000503:physiopathology*; D004285:Dogs; D017809:Fatal Outcome; D006652:Histological Techniques; D006934:Hypercalcemia / Q000503:physiopathology / Q000662:veterinary*; D007049:Iatrogenic Disease / Q000662:veterinary*; D011239:Prednisolone / Q000009:adverse effects
chemical_list: D011239:Prednisolone