[Mechanism of biotropic effects of regional electromagnetic fields in patients with left ventricular ischemic dysfunction].
OBJECTIVE
To study the role of disturbed autonomic regulation of the cardiovascular system in formation of the phenomenon of geliogeomagnetic sensitivity of patients with left ventricular ischemic dysfunction.


METHODS
24-h synchronous monitoring of ECG and electromagnetic situation was made in 11 patients (mean age 49.4 +/- 0.9 years) who had survived macrofocal myocardial infarction (MI) at least 6 months before and in 15 healthy volunteers.


RESULTS
Heart rhythm dispersion, correlation between variations of magnetic field vector component amplitudes and standard deviation of ECG R-R intervals duration in MI survivors were significantly less than in healthy subjects. High conjugacy of heart rhythm dispersion and mean value of R-R intervals (functions synchronization index) was characteristic only for the control group. A 3-week therapy with atenolol provided normalization of the disturbed correlations in 4 patients.


CONCLUSIONS
Pathogenic geliogeotropic reactions in MI survivors develop because of intra- and inter-systemic desynchronisation of the functions mechanism of which is mediated by sympathicoadrenal activation and is correctable by beta 1-adrenoblocker atenolol.
Bardak
A L
AL
Kaliuzhin
V V
VV
Kamaev
D Iu
DIu
Borodin
A S
AS
Pobachenko
S V
SV
Kolesnik
L I
LI
D000222:Adaptation, Physiological / Q000528:radiation effects; D001341:Autonomic Nervous System / Q000503:physiopathology* / Q000528:radiation effects; D015716:Electrocardiography, Ambulatory; D004574:Electromagnetic Fields / Q000009:adverse effects; D006801:Humans; D007238:Infarction / Q000150:complications / Q000503:physiopathology*; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology / Q000528:radiation effects; D018487:Ventricular Dysfunction, Left / Q000209:etiology* / Q000503:physiopathology