[Antioxidant system of the rat brain in toxic lung edema].
The state of enzymatic and nonenzymatic components of antioxidant system and also lipid peroxidation processes were studied in brain of rats with toxic pulmonary edema induced by inhalation of nitric oxides. The changes in the state of antioxidant system components in brain accompanied the development of toxic pulmonary edema. The main changes were found in nonenzymatic components of the antioxidant system, particularly in thiol and disulfide groups. Lipid peroxidation processes were not activated during the toxic pulmonary edema.
Pluzhnikov
N N
NN
Research Center of Biological Defence, Institute of Military Medicine, Defence Ministry, St. Petersburg, 195043, Russia.
Tiaptin
A A
AA
Zemlianoĭ
A V
AV
Varlashova
M B
MB
Torkunov
P A
PA
Lupachev
Iu A
IuA
D000280:Administration, Inhalation; D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D015227:Lipid Peroxidation; D008297:Male; D009589:Nitrogen Oxides; D011041:Poisoning / Q000378:metabolism; D011654:Pulmonary Edema / Q000139:chemically induced / Q000378:metabolism*; D051381:Rats
D000975:Antioxidants; D009589:Nitrogen Oxides