The laboratory diagnosis of gonorrhoea and syphilis infection.
Following a decline in prevalence during the 1980s and early 1990s, gonorrhoea and syphilis infections are once again posing a threat to public health. In addition, the antibiotic sensitivity pattern for gonorrhoea appears to have changed with an increased prevalence of resistance. Both syphilis and gonorrhoea appear to disproportionately affect MSM and black ethnic minorities, and are concentrated in urban areas. Their diagnosis requires microbiological tests to be performed appropriately, and a rapid diagnosis can often be provided in GUM clinics using near-patient microscopy. Early diagnosis and effective, rapid treatment is crucial in limiting the morbidity for the affected individual and the public health risks resulting from the spread of infection.
Chan
Edward L
EL
Department of Pathology, Baptist Medical Center-Montclair, Birmingham, AL 35213-1984, USA. Edward.Chan@BHSALA.com
Kingston
Margaret A
MA
Carlin
Elizabeth M
EM
D000328:Adult; D000942:Antigens, Bacterial / Q000032:analysis; D001431:Bacteriological Techniques; D015342:DNA Probes; D042241:Early Diagnosis; D006069:Gonorrhea / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D006801:Humans; D009344:Neisseria gonorrhoeae / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D015995:Prevalence; D013587:Syphilis / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D014210:Treponema pallidum / Q000302:isolation & purification*; D006113:United Kingdom / Q000453:epidemiology
D000942:Antigens, Bacterial; D015342:DNA Probes