Bilateral mesial temporal sclerosis and kernicterus.
Two children with mental retardation, choreoathetosis, dystonia, and muscle rigidity are reported. They had a history of severe hyperbilirubinemia after birth as a result of Rh isoimmunization. The history and clinical picture suggested the diagnosis of kernicterus. The magnetic resonance imaging examination showed a bilateral signal intensity increase in the globus pallidus on T2-weighted images. Additionally, our patients showed symmetric bilateral hyperintensity and volume loss in the hippocampus, which is known to be another characteristic area of bilirubin deposition in kernicterus.
Paksoy
Yahya
Y
Ultra Görüntüleme Merkezi (Imaging Center), Konya, Turkey. yahyapaksoy@yahoo.com
Koç
Hasan
H
Genç
Bülent Oğuz
BO
D002648:Child; D002675:Child, Preschool; D005260:Female; D005917:Globus Pallidus / Q000473:pathology; D006624:Hippocampus / Q000473:pathology; D006801:Humans; D007647:Kernicterus / Q000175:diagnosis / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D012598:Sclerosis; D013702:Temporal Lobe / Q000473:pathology*