CD4+ and CD8+ T-lymphocyte subsets in Zambian children.
Age-related changes in lymphocyte subsets in HIV-uninfected Zambian children are described. The total lymphocyte count and numbers of CD4+ and CD8+ T-lymphocytes declined with increasing age, while the percentage of CD4+ and CD8+ T-lymphocytes changed little during childhood. Girls between the ages of 12 and 71 months had a higher percentage of CD4+ T-lymphocytes and a higher CD4:CD8 ratio than did boys of a similar age.
Ndhlovu
Zaza
Z
Virology Laboratory, University Teaching Hospital, Lusaka, Zambia.
Ryon
Judith J
JJ
Griffin
Diane E
DE
Monze
Mwaka
M
Kasolo
Francis
F
Moss
William J
WJ
D017677:Age Distribution; D018791:CD4 Lymphocyte Count; D018414:CD8-Positive T-Lymphocytes; D002648:Child; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000276:immunology*; D006801:Humans; D007223:Infant; D008297:Male; D017678:Sex Distribution; D015024:Zambia