Tear clearance implications for ocular surface health.
Tear clearance/turnover provides a global assessment of the function of the lacrimal functional unit and of tear exchange on the ocular surface. It is an indirect measure of dry eye induced inflammation on the ocular surface. It shows better correlation with the severity of ocular irritation symptoms and corneal epithelial disease in dry eye than the Schirmer 1 test. Delayed tear clearance may prove to be the best measure for identifying patients with tear film disorders who may respond to anti-inflammatory therapy.
de Paiva
Cintia Sade
CS
Ocular Surface Center, Department of Ophthalmology, Baylor College Of Medicine, Houston, TX, USA.
Pflugfelder
Stephen C
SC
D003941:Diagnostic Techniques, Ophthalmological; D015352:Dry Eye Syndromes / Q000175:diagnosis*; D015590:Fluorophotometry / Q000379:methods; D006801:Humans; D013666:Tears / Q000502:physiology*