title: Extended radical resection versus standard resection for pancreatic cancer: the rationale for extended radical resection.
abstract: OBJECTIVE
  This clinical study was carried out to clarify the indications for extended radical resection for pancreatic carcinoma.
  
  
  METHODS
  From July 1981 to September 2003, 250 of 391 (63.9%) patients with pancreatic carcinoma underwent tumor resection in our department. Portal vein resection was performed in 171 of these 250 (68.4%) resected cases. The postoperative survival rate was studied using the operative and histologic findings.
  
  
  RESULTS
  Most of the patients who survived for 2 or 3 years were in the carcinoma-free surgical margins group.
  
  
  CONCLUSIONS
  The most important indication for an extended radical resection combined with portal vein resection for pancreatic cancer is the ability to obtain surgical cancer-free margins. There is no indication for an extended resection in patients in whom the surgical margins will become cancer positive if such an operation is employed.
authors.affiliation: Department of Surgery II, Nagoya University Hospital, Nagoyashi, Japan. nakaoaki@med.nagoya-u.ac.jp
authors.forename: Akimasa
authors.initials: A
authors.lastname: Nakao
authors.forename: Shin
authors.initials: S
authors.lastname: Takeda
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Sakai
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Kaneko
authors.forename: Soichiro
authors.initials: S
authors.lastname: Inoue
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Sugimoto
authors.forename: Naohito
authors.initials: N
authors.lastname: Kanazumi
mesh_terms: D021441:Carcinoma, Pancreatic Ductal / Q000401:mortality / Q000601:surgery*; D006801:Humans; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000601:surgery*; D011169:Portal Vein / Q000601:surgery; D016019:Survival Analysis