[Treatment of steroid-dependent minimal change-nephrotic syndrome with mycophenolate mofetil].
Here we report two male patients, 16 and 20 years-old respectively, with minimal-change nephrotic syndrome showing frequent relapses and steroid dependence. Treatment with cyclosporin did not prevent the appearance of new relapses and both patients developed cyclosporin-dependence. The introduction of mycophenolate mofetil (500-15,000 mg/day) was followed by a sustained complete remission in both cases, without secondary effects.
Noroña
B
B
Servicio de Nefrología, Hospital 12 de Octubre, Madrid.
Valentín
M
M
Gutiérrez
E
E
Praga
M
M
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D009173:Mycophenolic Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D009402:Nephrosis, Lipoid / Q000188:drug therapy*
D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid