title: High-resolution functional optical imaging: from the neocortex to the eye.
abstract: Much work remains to be done to establish the clinical usefulness of the RFI for early diagnosis and treatment guidance. The discoveries obtained by functional optical imaging of the neocortex in the last 15 years and the recent RFI studies of the eyes of normal subjects and patients with diabetic retinopathy, glaucoma, and age-related macular degeneration suggest that functional optical imaging of the retina is likely to become a multi-modality powerful clinical tool.
authors.affiliation: Department of Neurobiology, The Weizmann Institute of Science, The Grodetsky Center for Research of Higher Brain Functions, Rehovot, Israel. Amiram.Grinvald@weizmann.weizmann.ac.il
authors.forename: Amiram
authors.initials: A
authors.lastname: Grinvald
authors.forename: Tobias
authors.initials: T
authors.lastname: Bonhoeffer
authors.forename: Ivo
authors.initials: I
authors.lastname: Vanzetta
authors.forename: Ayala
authors.initials: A
authors.lastname: Pollack
authors.forename: Eyal
authors.initials: E
authors.lastname: Aloni
authors.forename: Ron
authors.initials: R
authors.lastname: Ofri
authors.forename: Darin
authors.initials: D
authors.lastname: Nelson
mesh_terms: D000818:Animals; D001931:Brain Mapping; D003952:Diagnostic Imaging / Q000295:instrumentation; D004867:Equipment Design; D006801:Humans; D019579:Neocortex / Q000033:anatomy & histology* / Q000098:blood supply / Q000502:physiology*; D055095:Optics and Photonics / Q000295:instrumentation; D010092:Oximetry / Q000379:methods; D012039:Regional Blood Flow; D012160:Retina / Q000033:anatomy & histology*; D012171:Retinal Vessels / Q000033:anatomy & histology / Q000502:physiology*