title: The pre-BCR checkpoint as a cell-autonomous proliferation switch.
authors.affiliation: Department of Immunology, Erasmus MC Rotterdam, PO Box 1738, NL-3000 DR Rotterdam, The Netherlands. r.hendriks@erasmusmc.nl
authors.forename: Rudi W
authors.initials: RW
authors.lastname: Hendriks
authors.forename: Sabine
authors.initials: S
authors.lastname: Middendorp
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D000077329:Agammaglobulinaemia Tyrosine Kinase; D020816:Amino Acid Motifs; D000818:Animals; D001402:B-Lymphocytes / Q000166:cytology / Q000276:immunology*; D002352:Carrier Proteins / Q000502:physiology; D002455:Cell Division / Q000502:physiology; D005803:Genes, Immunoglobulin; D006801:Humans; D007134:Immunoglobulin Switch Region; D008213:Lymphocyte Activation; D016393:Lymphoma, B-Cell / Q000276:immunology / Q000473:pathology; D051379:Mice; D018345:Mice, Knockout; D018448:Models, Immunological; D009097:Multienzyme Complexes / Q000502:physiology; D010750:Phosphoproteins / Q000172:deficiency / Q000502:physiology; D010766:Phosphorylation; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000276:immunology / Q000473:pathology; D011499:Protein Processing, Post-Translational; D011505:Protein-Tyrosine Kinases / Q000502:physiology; D011947:Receptors, Antigen, B-Cell / Q000276:immunology*; D020395:Receptors, Interleukin-7 / Q000502:physiology; D015398:Signal Transduction
chemical_list: D048868:Adaptor Proteins, Signal Transducing; C113939:B cell linker protein; D002352:Carrier Proteins; D009097:Multienzyme Complexes; D010750:Phosphoproteins; D011947:Receptors, Antigen, B-Cell; D020395:Receptors, Interleukin-7; D011505:Protein-Tyrosine Kinases; D000077329:Agammaglobulinaemia Tyrosine Kinase