An update on corneal hydration control.
An account is provided of developments in our understanding of the mechanism of corneal hydration control, particularly as regards the possibility of an active system for its regulation. Emphasis is given to issues that are contentious, such as the role of bicarbonate in the endothelial pump and the significance of water channels in both corneal limiting cell layers.
Fischbarg
Jorge
J
Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA. jf20@columbia.edu
Maurice
David M
DM
D027321:Anion Transport Proteins / Q000502:physiology; D001639:Bicarbonates / Q000378:metabolism; D001834:Body Water / Q000378:metabolism*; D002463:Cell Membrane Permeability / Q000502:physiology; D003315:Cornea / Q000378:metabolism*; D004728:Endothelium, Corneal / Q000378:metabolism; D019573:Epithelium, Corneal / Q000378:metabolism; D006801:Humans
D027321:Anion Transport Proteins; D001639:Bicarbonates