Injected calcium sulfate for consolidation of distraction osteogenesis in rabbit tibia.
This study investigated the effects of calcium sulfate powder injection in a rabbit tibial distraction model. There was one experimental group and two control groups. The calcium sulfate powder, suspended in carboxymethylcellulose (CMC) medium, was injected into the distracted tissue in the experimental rabbit group, whereas only CMC medium was injected into the one control group. The other control group did not undergo any intervention. On radiography and bone mineral density tests, the amount of newly formed bone was greater in the distracted zone of the experimental group than in the two control groups, which showed incomplete bone deposition and calcification. The application of calcium sulfate to distracted tissue increased the rate of osteogenesis and calcification.
Song
Hae-Ryong
HR
Department of Orthopedic Surgery, Gyeongsang National University Hospital, Chinju, South Korea.
Oh
Chang-Wug
CW
Kyung
Hee-Soo
HS
Park
Il-Hyung
IH
Kim
Poong-Taek
PT
Baek
Seung-Hoon
SH
Kim
Sung-Jung
SJ
Lee
Sung-Tae
ST
D000818:Animals; D015519:Bone Density; D018786:Bone Substitutes / Q000494:pharmacology*; D002113:Calcification, Physiologic / Q000187:drug effects / Q000502:physiology; D002133:Calcium Sulfate / Q000494:pharmacology*; D007267:Injections; D023421:Models, Animal; D010012:Osteogenesis / Q000187:drug effects / Q000502:physiology; D019857:Osteogenesis, Distraction / Q000379:methods*; D011817:Rabbits; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging / Q000601:surgery*
D018786:Bone Substitutes; D002133:Calcium Sulfate