A systematic review of symptomatic outcomes used in oesophagitis drug therapy trials.
Symptoms are an important outcome for measurement in clinical trials into gastro-oesophageal reflux disease, but the optimal approach to symptom assessment has not been formally evaluated. The authors conducted a systematic review to assess how reflux symptoms have been evaluated and how well these correlate with oesophagitis healing and relapse.
Sharma
N
N
Gastroenterology Unit, City Hospital, Dudley Road, Winson Green, Birmingham, UK.
Donnellan
C
C
Preston
C
C
Delaney
B
B
Duckett
G
G
Moayyedi
P
P
D002986:Clinical Trials as Topic; D004941:Esophagitis / Q000188:drug therapy*; D005764:Gastroesophageal Reflux / Q000188:drug therapy*; D006801:Humans; D011788:Quality of Life; D012008:Recurrence; D016896:Treatment Outcome