title: [Treatment of steroid-dependent minimal change-nephrotic syndrome with mycophenolate mofetil].
abstract: Here we report two male patients, 16 and 20 years-old respectively, with minimal-change nephrotic syndrome showing frequent relapses and steroid dependence. Treatment with cyclosporin did not prevent the appearance of new relapses and both patients developed cyclosporin-dependence. The introduction of mycophenolate mofetil (500-15,000 mg/day) was followed by a sustained complete remission in both cases, without secondary effects.
authors.affiliation: Servicio de Nefrología, Hospital 12 de Octubre, Madrid.
authors.forename: B
authors.initials: B
authors.lastname: Noroña
authors.forename: M
authors.initials: M
authors.lastname: Valentín
authors.forename: E
authors.initials: E
authors.lastname: Gutiérrez
authors.forename: M
authors.initials: M
authors.lastname: Praga
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D009173:Mycophenolic Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D009402:Nephrosis, Lipoid / Q000188:drug therapy*
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid