title: Necrobiotic xanthogranuloma associated with myeloma.
abstract: We observed a 73-year-old man with necrobiotic xanthogranuloma (NXG) on the eyelids and concurrent multiple myeloma. The treatment was surgery followed by administration of melphalan. No relapse was seen in 19 months of follow-up. We consider that surgical removal of xanthogranuloma is an advisable rapid treatment that involves fewer side-effects than other treatments.
authors.affiliation: Department of Dermatology, Hospital de León, C/Altos de Nava s/n, 24008 León, Spain. mmartinezf@hleo.sacyl.es
authors.forename: M
authors.initials: M
authors.lastname: Martínez Fernández
authors.forename: M A
authors.initials: MA
authors.lastname: Rodríguez Prieto
authors.forename: I
authors.initials: I
authors.lastname: Ruiz González
authors.forename: P
authors.initials: P
authors.lastname: Sánchez Sambucety
authors.forename: S
authors.initials: S
authors.lastname: Delgado Vicente
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D001774:Blood Chemical Analysis; D005500:Follow-Up Studies; D016460:Granuloma Annulare / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008558:Melphalan / Q000627:therapeutic use; D009101:Multiple Myeloma / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D035583:Rare Diseases; D018570:Risk Assessment; D016896:Treatment Outcome; D014973:Xanthomatosis / Q000150:complications / Q000188:drug therapy / Q000473:pathology*
chemical_list: D008558:Melphalan