Crigler-Najjar syndrome type 1 associated with combined 1070A-->G, Q357R and (TA)7 mutation in Kuwaiti Bedouin families indicate a founder effect in Arabs.
Koshy
Abraham
A
Bosma
Piter J
PJ
Oude-Elferink
Ronald P J
RP
D018912:Arabs; D001483:Base Sequence; D002648:Child; D003414:Crigler-Najjar Syndrome / Q000235:genetics*; D004252:DNA Mutational Analysis; D005091:Exons / Q000235:genetics; D005192:Family Health; D018703:Founder Effect; D014453:Glucuronosyltransferase / Q000235:genetics*; D006801:Humans; D007730:Kuwait; D009154:Mutation; D000099148:UGT1A1 Enzyme
D014453:Glucuronosyltransferase; D000099148:UGT1A1 Enzyme