P-31 magnetic resonance spectroscopy. A tool for diagnostic purposes and pathophysiological insights in muscle diseases.
31P Magnetic Resonance Spectroscopy (MRS) is a potent tool allowing the investigation of muscle energetics in a noninvasive manner in humans. This review details the contribution of 31P MRS to the diagnosis of metabolic myopathies and provides some clues for the use of this technique in a clinical perspective. Finally, the contribution of 31P MRS to our understanding of the physiopathology of several other diseases is highlighted.
Mattei
J P
JP
Centre de Résonance Magnétique Biologique et Médicale, CRMBM, UMR-CNRS 6612, Faculté de Médecine, Marseille, France. matteijp@club-internet.fr
Bendahan
D
D
Cozzone
P
P
D006019:Glycolysis; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D028361:Mitochondrial Diseases / Q000175:diagnosis; D009135:Muscular Diseases / Q000175:diagnosis* / Q000503:physiopathology*; D010759:Phosphorus Isotopes
D010759:Phosphorus Isotopes