Synergistic action of photosensitizers and normal human serum in a bactericidal process. I. Effect of chlorophylls.
Susceptibility of some Gram-negative strains against the bactericidal action of normal human serum (NHS) and of chlorophyll, which induces production of reactive oxygen species by light, was studied. A synergistic bactericidal activity of NHS and chlorophyll against E. coli K1 and Shigella flexneri strains was observed.
Jankowski
Andrzej
A
Institute of Biotechnology and Environment Protection, University of Zielona Góra, Monte Cassino 21b, 65-561 Zielona Góra, Poland. JJJ@WCHUWR.CHEM.UNI.WROC.Pl
Jankowski
Stanisław
S
Mirończyk
Agnieszka
A
D001412:Bacillus subtilis / Q000187:drug effects*; D001770:Blood Bactericidal Activity / Q000187:drug effects*; D002734:Chlorophyll / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects*; D006801:Humans; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000494:pharmacology*; D017382:Reactive Oxygen Species / Q000494:pharmacology; D044967:Serum / Q000502:physiology; D012763:Shigella flexneri / Q000187:drug effects*
D017319:Photosensitizing Agents; D017382:Reactive Oxygen Species; D002734:Chlorophyll