Retinal vascular abnormalities in CADASIL.
To assess retinal vascular alterations in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, the authors examined 10 affected individuals with ophthalmologic evaluation including fluorescence angiography. Findings included bilateral peripapillary arteriolar sheathing (30%), arteriolar narrowing (80%), and arteriovenous nicking (90%). No retinal infarcts, vascular occlusions, exudation, or hypoperfusion of affected vessels were found.
Haritoglou
C
C
Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany.
Rudolph
G
G
Hoops
J P
JP
Opherk
C
C
Kampik
A
A
Dichgans
M
M
D000328:Adult; D000368:Aged; D001160:Arterioles / Q000473:pathology*; D015161:Dementia, Multi-Infarct / Q000150:complications* / Q000235:genetics / Q000473:pathology; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D011518:Proto-Oncogene Proteins / Q000235:genetics; D011956:Receptors, Cell Surface / Q000235:genetics; D012016:Reference Values; D012164:Retinal Diseases / Q000150:complications* / Q000175:diagnosis*; D012171:Retinal Vessels / Q000473:pathology*; D014787:Vision Tests
D011518:Proto-Oncogene Proteins; D011956:Receptors, Cell Surface; D007208:Indocyanine Green