title: Chemotaxis and flagellar genes of Chromobacterium violaceum.
abstract: The availability of the complete genome of the Gram-negative beta-proteobacterium Chromobacterium violaceum has increasingly impacted our understanding of this microorganism. This review focuses on the genomic organization and structural analysis of the deduced proteins of the chemosensory adaptation system of C. violaceum. C. violaceum has multiple homologues of most chemotaxis genes, organized mostly in clusters in the bacterial genome. We found at least 67 genes, distributed in 10 gene clusters, involved in the chemotaxis of C. violaceum. A close examination of the chemoreceptors methyl-accepting chemotaxis proteins (MCPs), and the deduced sequences of the members of the two-component signaling system revealed canonical motifs, described as essential for the function of the deduced proteins. The chemoreceptors found in C. violaceum include the complete repertoire of such genes described in bacteria, designated as tsr, tar, trg, and tap; 41 MCP loci were found in the C. violaceum genome. Also, the C. violaceum genome includes a large repertoire of the proteins of the chemosensory transducer system. Multiple homologues of bacterial chemotaxis genes, including CheA, CheB, CheD, CheR, CheV, CheY, CheZ, and CheW, were found in the C. violaceum genome.
authors.affiliation: Laboratório de Biologia Molecular, Universidade Federal de Goiás, 74001-970 Goiânia, GO, Brasil.
authors.forename: Maristela
authors.initials: M
authors.lastname: Pereira
authors.forename: Juliana Alves
authors.initials: JA
authors.lastname: Parente
authors.forename: Luiz Artur Mendes
authors.initials: LA
authors.lastname: Bataus
authors.forename: Divina das Dores de Paula
authors.initials: Dd
authors.lastname: Cardoso
authors.forename: Renata Bastos Ascenço
authors.initials: RB
authors.lastname: Soares
authors.forename: Célia Maria de Almeida
authors.initials: CM
authors.lastname: Soares
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics* / Q000502:physiology; D002633:Chemotaxis / Q000235:genetics* / Q000502:physiology; D002861:Chromobacterium / Q000235:genetics* / Q000502:physiology; D005407:Flagella / Q000235:genetics* / Q000502:physiology; D005798:Genes, Bacterial / Q000235:genetics* / Q000502:physiology; D016680:Genome, Bacterial; D008565:Membrane Proteins / Q000235:genetics / Q000502:physiology; D000072236:Methyl-Accepting Chemotaxis Proteins
chemical_list: D001426:Bacterial Proteins; D008565:Membrane Proteins; D000072236:Methyl-Accepting Chemotaxis Proteins