Immunotoxicological consequences of perinatal chemical exposures.
The developing immune system may be especially vulnerable to the toxic effects of immunotoxicants. A number of chemicals has been identified that affect the developing immune system. Yet, so far there are no immune parameters included in current guidelines for developmental or reproductive toxicity testing. It is recommended that such guidelines are updated so that also the developing immune system is evaluated as a potential target of toxicity during developmental stages.
Van Loveren
Henk
H
National Institute of Public Health and Environment, PO Box 1, 3730 BA, Bilthoven, The Netherlands. h.van.loveren@rivm.nl
Piersma
Aldert
A
D000818:Animals; D000831:Animals, Newborn / Q000276:immunology*; D006128:Growth / Q000187:drug effects; D007107:Immune System / Q000187:drug effects* / Q000254:growth & development / Q000276:immunology; D000922:Immunotoxins / Q000633:toxicity*; D012107:Research Design
D000922:Immunotoxins