Neurovirulence of four encephalitogenic dengue 3 virus strains isolated in Malaysia (1992-1994) is not attributed to their envelope protein.
The amino acid sequences of the envelope (E) protein of four encephalitogenic and five non-encephalitogenic dengue 3 virus strains isolated in Malaysia were determined and compared. Multiple sequence alignment revealed a high degree of similarity in the E protein of the strains suggesting that neurovirulence of these four encephalitogenic strains is not attributed to this protein.
Fong
Mun-Yik
MY
Department of Parasitology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. fongmy@um.edu.my
Yusup
Roziyah
R
Yusof
Rohana
R
Lam
Sai-Kit
SK
D000595:Amino Acid Sequence; D003715:Dengue / Q000821:virology*; D003716:Dengue Virus / Q000145:classification / Q000472:pathogenicity*; D018792:Encephalitis, Viral / Q000821:virology*; D006801:Humans; D008969:Molecular Sequence Data; D014759:Viral Envelope Proteins / Q000235:genetics*; D014774:Virulence
D014759:Viral Envelope Proteins