title: Acute aortic dissection versus aortic root aneurysm: comparison of indications for valve sparing aortic root reconstruction.
abstract: OBJECTIVE
  To prove whether different indications for valve sparing aortic root reconstruction may have an impact on the outcome and longevity of the repair.
  
  
  METHODS
  From July 1993 to March 2003, the reimplantation technique for valve sparing aortic root reconstruction was applied to 232 patients. In 44 patients, indication for operation was acute aortic dissection type A (AADA). These patients were compared with 44 randomised patients operated for aortic root aneurysm (root) by matched pair analysis with respect to age, gender, time point of operation and presence of Marfan's syndrome. Peri- and post-operative courses with focus on survival and valvular stability were analysed.
  
  
  RESULTS
  Pre-operative grade of aortic insufficiency was 2.4+/-1 in root vs. 1.5+/-1.7 in AADA (P = 0.004) Mean CPB-time (214+/-60 vs. 171+/-42 min;P < 0.001), aortic cross clamp time (158+/-40 vs. 129+/-39 min; P = 0.001) and stay on ICU (5.2+/-9 vs. 1.7+/-1 days; P = 0.034) were longer for AADA, while hospitalisation was comparable (14+/-10 vs. 14+/-7 days; P = 0.88). Five patients (11.4%) from AADA died peri-operatively compared to no patient from root (P = 0.055). None of the early deaths were valve-related. Re-thoracotomy rate was 6.8% for both groups. Mean follow-up was 19+/-21 months for AADA vs. 28+/-21 months for root (P = 0.038) Survival at 3 years was 88+/-5% for AADA and 100% for root (P = 0.028). Freedom from valvular reoperation was 97+/-2.7% for root and 97+/-3% for AADA at 3 years (P = 0.44). At last investigation, mean grade of aortic insufficiency for AADA was 0.2+/-0.3 compared to 0.3+/-0.3 for root (P = 0.34)
  
  
  CONCLUSIONS
  Regardless of the underlying indication, the aortic valve preserving reimplantation technique can be performed with favourable functional results.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany. kallenbach@thg.mh-hannover.de
authors.forename: K
authors.initials: K
authors.lastname: Kallenbach
authors.forename: R G
authors.initials: RG
authors.lastname: Leyh
authors.forename: R
authors.initials: R
authors.lastname: Salcher
authors.forename: M
authors.initials: M
authors.lastname: Karck
authors.forename: C
authors.initials: C
authors.lastname: Hagl
authors.forename: A
authors.initials: A
authors.lastname: Haverich
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000784:Aortic Dissection / Q000601:surgery*; D001014:Aortic Aneurysm / Q000601:surgery*; D001021:Aortic Valve / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008382:Marfan Syndrome / Q000601:surgery; D016555:Matched-Pair Analysis; D008875:Middle Aged; D016019:Survival Analysis; D016896:Treatment Outcome