title: Endovascular management of a mandibular arteriovenous malformation in a patient with severe hemophilia a.
abstract: The unusual case of a mandibular arteriovenous malformation in a patient with severe hemophilia A and hepatitis C is reported. Supplementary substitution of various coagulation factors allowed direct puncture and intralesional injection of a liquid adhesive, resulting in complete anatomic and clinical cure without peri- or postoperative bleeding. Replacement therapy providing normal levels of relevant coagulation factors enables endovascular treatment in a safe and effective manner in hemophiliac patients.
authors.affiliation: Department of Radiology, Virchow Hospital, Charité, Humboldt University, Berlin, Germany.
authors.forename: Goetz
authors.initials: G
authors.lastname: Benndorf
authors.forename: Doris M
authors.initials: DM
authors.lastname: Kim
authors.forename: Horst
authors.initials: H
authors.lastname: Menneking
authors.forename: Martin
authors.initials: M
authors.lastname: Klein
mesh_terms: D000328:Adult; D000792:Angiography; D001165:Arteriovenous Malformations / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D001779:Blood Coagulation Factors / Q000008:administration & dosage; D001780:Blood Coagulation Tests; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic; D004659:Enbucrilate / Q000627:therapeutic use; D005169:Factor VIII / Q000008:administration & dosage; D006467:Hemophilia A / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008297:Male; D008334:Mandible / Q000098:blood supply*
chemical_list: D001779:Blood Coagulation Factors; C025667:prothrombin complex concentrates; D005169:Factor VIII; D004659:Enbucrilate