title: Pulmonary stretch receptor activity during Partial Liquid Ventilation in Cats with Healthy Lungs.
abstract: OBJECTIVE
  To study whether pulmonary stretch receptor (PSR) activity in mechanically ventilated young cats with healthy lungs during partial liquid ventilation (PLV) is different from that during gas ventilation (GV).
  
  
  METHODS
  In 10 young cats (4.4 +/- 0.4 months, 2.3 +/- 0.3 kg; mean +/- SD), PSR instantaneous impulse frequency (PSR fimp) was recorded from single fibres in the vagal nerve during GV and PLV with perfluorocarbon (30 ml/kg) at increasing positive inspiratory pressures (PIP; 1.2, 1.8, 2.2 and 2.7 kPa), and at a positive end-expiratory pressure of 0.5 kPa.
  
  
  RESULTS
  All PSRs studied during GV maintained their phasic character with increased impulse frequency during inspiration during PLV. Peak PSRfimp was lower at PIP 1.2 kPa (p < 0.05) and at PIP 2.7 kPa (p = 0.10) during PLV than during GV, giving a lower number of PSR impulses at these two settings during PLV (p < 0.05).
  
  
  CONCLUSIONS
  The phasic character of PSR activity is similar during GV and PLV. PSR activity is not higher during PLV than during GV in cats with healthy lungs, indicating no extensive stretching of the lung during PLV.
authors.affiliation: Department of Women's and Children's Health and Department of Physiology, Uppsala University, Uppsala, Sweden. ester.fackeldey@kbh.uu.se
authors.forename: Esther
authors.initials: E
authors.lastname: Rieger-Fackeldey
authors.forename: Richard
authors.initials: R
authors.lastname: Sindelar
authors.forename: Anders
authors.initials: A
authors.lastname: Jonzon
authors.forename: Andreas
authors.initials: A
authors.lastname: Schulze
authors.forename: Gunnar
authors.initials: G
authors.lastname: Sedin
mesh_terms: D000818:Animals; D001158:Arteries; D001696:Biomechanical Phenomena; D002415:Cats; D021061:Liquid Ventilation; D008168:Lung / Q000502:physiology*; D010100:Oxygen / Q000097:blood; D011661:Pulmonary Stretch Receptors / Q000502:physiology*; D012121:Respiration, Artificial
chemical_list: D010100:Oxygen