title: Measurement of density and chemical concentration using a microfluidic chip.
abstract: A new microfluidic product for measuring fluid density, specific gravity and chemical concentration has been developed. At the core of this lab-on-a-chip sensor is a vacuum-sealed resonating silicon microtube. Measurements can be made with under a microliter of sample fluid, which is over 1000x less than is conventionally required. Since the product is MEMS-based the overall system size is a fraction of conventional density meters and it weighs much less than the traditional desk-top, temperature controlled, density meters. The syringe or pipette loaded system includes a dynamic temperature control system that operates between 0 degree C and 90 degree C with an accuracy of less than 0.01 degree C. Density measurement accuracies of 4 to 5 digits have been observed with aqueous solutions. Measurement examples and applications will be discussed.
authors.affiliation: Integrated Sensing Systems Inc, 391 Airport Industrial Dr, Ypsilanti, MI 48198, USA. dsparks@mems-issys.com
authors.forename: D
authors.initials: D
authors.lastname: Sparks
authors.forename: R
authors.initials: R
authors.lastname: Smith
authors.forename: M
authors.initials: M
authors.lastname: Straayer
authors.forename: J
authors.initials: J
authors.lastname: Cripe
authors.forename: R
authors.initials: R
authors.lastname: Schneider
authors.forename: A
authors.initials: A
authors.lastname: Chimbayo
authors.forename: S
authors.initials: S
authors.lastname: Anasari
authors.forename: N
authors.initials: N
authors.lastname: Najafi
mesh_terms: D004867:Equipment Design; D000432:Methanol / Q000737:chemistry; D008832:Microchemistry / Q000295:instrumentation / Q000379:methods; D044085:Microfluidics / Q000295:instrumentation / Q000379:methods; D012822:Silicon Dioxide; D012996:Solutions / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D012996:Solutions; D012822:Silicon Dioxide; D000432:Methanol