[Two children seriously weakened by myasthenia].
Two boys, aged 2 and 11 years, presented with fever and muscle weakness that resulted in respiratory insufficiency. A physical examination and additional tests confirmed the diagnosis 'myasthenia'. Acetyl cholinesterase-inhibitor therapy had a favourable effect. Myasthenia is a diagnosis that should be considered for every child presenting with muscle weakness of unknown origin.
Schrijver-Levie
N S
NS
Afd. Kindergeneeskunde, Medisch Centrum, Alkmaar.
Boersma
B
B
ten Houten
R
R
D002648:Child; D002675:Child, Preschool; D018680:Cholinergic Antagonists / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D005334:Fever; D006801:Humans; D008297:Male; D018908:Muscle Weakness; D009157:Myasthenia Gravis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D009426:Netherlands; D009460:Neurologic Examination; D011950:Receptors, Cholinergic / Q000276:immunology*; D012131:Respiratory Insufficiency / Q000209:etiology
D018680:Cholinergic Antagonists; D011950:Receptors, Cholinergic