Concomitant occurrence of MALT lymphoma and multiple myeloma.
The association between multiple myeloma and secondary malignancies is already well established. We report here on the concomitant occurrence of mucosa-associated lymphoid tissue (MALT) lymphoma and multiple myeloma. Despite the fact that both malignancies are mature B-cell neoplasms, the clinical approach to these two types of tumor is completely different. This paper describes the diagnostic approach to this particular case and presents immunophenotypic and molecular cytogenetic data suggesting that the two B-cell malignancies were clonally unrelated.
Wöhrer
Stefan
S
Clinical Division of Oncology, Department of Medicine I, University Hospital Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria. stefan.woehrer@meduniwien.ac.at
Raderer
Markus
M
Streubel
Berthold
B
Chott
Andreas
A
Drach
Johannes
J
D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D005123:Eye / Q000473:pathology; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008297:Male; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D014055:Tomography, Emission-Computed