Dietary intake of hexachlorobenzene in Catalonia, Spain.
To assess the dietary intake of hexachlorobenzene (HCB) by the population of Catalonia, Spain, a total-diet study was carried out. Concentrations of HCB were determined in food samples randomly acquired in seven cities of Catalonia between June and August 2000. A total of 11 food groups were included in the study. HCB levels were determined by HRGC/HRMS. Estimates of average daily food consumption were obtained from recent studies. HCB intake was estimated for five population groups: children (aged 4 to 9 years), adolescents (aged 10 to 19 years), male and female adults (aged 20 to 65 years), and seniors (aged >65 years). In general, HCB residues in foods were rather low excepting dairy products with a mean concentration of 0.869 ng/g wet weight. Total dietary intakes of HCB (microgram per kilogram body weight/day) were the following: children (0.0064), adolescents (0.0031), female adults (0.0025), male adults (0.0024) and seniors (0.0019). All these values are considerably lower than the WHO tolerable daily intake (TDI), which is 0.17 microg kg(-1) day(-1) for non-cancer effects and 0.16 microg kg(-1) day(-1) for neoplastic effects in humans.
Falcó
G
G
Toxicology Unit, School of Pharmacy, University of Barcelona, Av. Joan XXIII, s/n, Barcelona 08028, Spain.
Bocio
A
A
Llobet
J M
JM
Domingo
J L
JL
Casas
C
C
Teixidó
A
A
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003611:Dairy Products; D003625:Data Collection; D004032:Diet; D004781:Environmental Exposure; D005260:Female; D005506:Food Contamination; D005659:Fungicides, Industrial / Q000032:analysis*; D006581:Hexachlorobenzene / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013030:Spain
D005659:Fungicides, Industrial; D006581:Hexachlorobenzene