title: [Bioequivalence and therapeutic equivalence in psychiatry].
abstract: Many psychotropics on the market are generic forms and essentially similar products. Bioequivalence is the method used in order to demonstrate the therapeutic equi-valence between the reference drug and the new product. The principles, methods and limits of these studies are presented and illustrated by some examples for CNS drugs.
authors.affiliation: Institut des Neurosciences Physiologiques et Cognitives, Faculté de Médecine, FRE 2109 CNRS-Université de la Méditerranée, Assistance Publique Hôpitaux de Marseille, 13385 Marseille, cedex 5, France.
authors.forename: C
authors.initials: C
authors.lastname: Couprie
authors.lastname: Lacarelle
authors.lastname: Blin
mesh_terms: D014151:Anti-Anxiety Agents / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D000928:Antidepressive Agents / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D001007:Anxiety / Q000188:drug therapy*; D000697:Central Nervous System Stimulants / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D003863:Depression / Q000188:drug therapy*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D013810:Therapeutic Equivalency
chemical_list: D014151:Anti-Anxiety Agents; D000928:Antidepressive Agents; D000697:Central Nervous System Stimulants; D006993:Hypnotics and Sedatives