A trial of omega-3 fatty acids for prevention of hypertension.
Although omega-3 polyunsaturated fatty acid supplements reduce blood pressure (BP), the typical doses cause untoward side effects. A novel fatty acid supplement was tested in a randomized trial of patients with high normal diastolic BP. The novel fatty acid supplement did not significantly reduce BP in patients with high normal diastolic blood pressure.
Dokholyan
Rachel S
RS
Duke Clinical Research Institute, Durham, North Carolina, USA. dokholyan@duke.edu
Albert
Christine M
CM
Appel
Lawrence J
LJ
Cook
Nancy R
NR
Whelton
Paul
P
Hennekens
Charles H
CH
D001794:Blood Pressure / Q000187:drug effects; D002214:Capsules; D004338:Drug Combinations; D015118:Eicosapentaenoic Acid / Q000008:administration & dosage* / Q000494:pharmacology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D017965:gamma-Linolenic Acid / Q000008:administration & dosage* / Q000494:pharmacology
D002214:Capsules; D004338:Drug Combinations; D017965:gamma-Linolenic Acid; D015118:Eicosapentaenoic Acid