Survey of prokinetic use in horses with gastrointestinal injury.
OBJECTIVE
To report prokinetic strategies used to manage horses after gastrointestinal surgery.


METHODS
Electronic questionnaire.


METHODS
Diplomates of the American College of Veterinary Surgeons (ACVS) who perform equine intestinal surgery.


METHODS
A survey (21 questions) designed to determine use of prokinetic agents was sent electronically to 112 ACVS Diplomates known to perform equine intestinal surgery. Several clinical scenarios were also described to determine which, if any, prokinetic agent respondents would select.


RESULTS
Responses were obtained from 58 (52%) surgeons from 44 clinics. Selection of prokinetic agent for specific gastrointestinal conditions was relatively uniform whereas there was considerable variation in dose administered. For postoperative ileus (POI) associated with most intestinal lesions, 2% lidocaine was most commonly selected. Other prokinetics in decreasing frequency of use were erythromycin lactobionate, metoclopramide, and cisapride. Prokinetic agents were more commonly administered after small intestine strangulating obstructions and less commonly for large intestinal lesions. No novel agents were identified by respondents.


CONCLUSIONS
Prokinetic drugs are commonly used for the management and/or attenuation of POI in horses, but dosages and routes of administration are variable.


CONCLUSIONS
Although prokinetics are commonly used for management of POI in horses there is clearly a need for more controlled studies to define efficacious dosing and a need to develop new prokinetic drugs.
Van Hoogmoed
Linda M
LM
Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA.
Nieto
Jorge E
JE
Snyder
Jack R
JR
Harmon
Faye A
FA
D000818:Animals; D020117:Cisapride / Q000008:administration & dosage; D004917:Erythromycin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D005765:Gastrointestinal Agents / Q000008:administration & dosage*; D005767:Gastrointestinal Diseases / Q000453:epidemiology / Q000601:surgery / Q000662:veterinary*; D006734:Horse Diseases / Q000453:epidemiology* / Q000601:surgery*; D006736:Horses / Q000502:physiology*; D006762:Hospitals, Animal / Q000706:statistics & numerical data; D045823:Ileus / Q000517:prevention & control / Q000662:veterinary; D008012:Lidocaine / Q000008:administration & dosage; D008787:Metoclopramide / Q000008:administration & dosage; D009388:Neostigmine / Q000008:administration & dosage; D011183:Postoperative Complications / Q000517:prevention & control / Q000662:veterinary; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology
D005765:Gastrointestinal Agents; C010948:erythromycin lactobionate; D009388:Neostigmine; D004917:Erythromycin; D008012:Lidocaine; D008787:Metoclopramide; D020117:Cisapride