Platinum dichloride-catalyzed cycloisomerization of ene-ynamides.
[reaction: see text] Various ene-tosylynamides react with platinum(II) chloride and lead to bicyclic nitrogenated heterocycles. This unprecedented and easily operated process can be coupled with a hydrolysis of the intermediate cyclic tosylenamides in a one-pot transformation, which provides cyclobutanones.
Marion
Frédéric
F
Laboratoire de Chimie Organique, Associé au CNRS, Université Pierre et Marie Curie, B. 229, 4 Place Jussieu, 75252 Paris Cedex 05, France.
Coulomb
Julien
J
Courillon
Christine
C
Fensterbank
Louis
L
Malacria
Max
M