Cerebellar liponeurocytoma: a case report and review of the literature.
Cerebellar liponeurocytoma has recently been recognised by the 2000 World Health Organisation classification of tumours of the central nervous system as a distinct clinicopathologic entity. To our knowledge, 18 cases have been reported so far, under different names, such as "lipomatous medulloblastoma, lipidized medulloblastoma, neurolipocytoma, medullocytoma and lipomatous glioneurocytoma". The new classification included cerebellar liponeurocytoma in the category of glioneuronal tumours grade I or II because of its favourable clinical behaviour. The origin and nature of the lipomatous component have been matter of debate and make this tumour entity puzzling. We describe a new case of liponeurocytoma removed from the left cerebellar hemisphere of a 38-year-old-woman. The patient showed unspecific signs of intracranial hypertension and symptoms suggesting a posterior fossa lesion.
Amina
M
M
Department of Pathology, Hospital La Rabta, 1007 Bab Saadoun, Tunis
Saadia
B
B
Kais
N
N
Hammouda Karim
B
B
Khadija
B
B
Slim
H
H
Moncef
Z
Z
Nidhameddine
K
K
D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D002454:Cell Differentiation; D002528:Cerebellar Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006801:Humans; D008055:Lipids / Q000032:analysis; D008067:Lipoma / Q000473:pathology*; D009363:Neoplasm Proteins / Q000032:analysis; D018306:Neurocytoma / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology*; D010751:Phosphopyruvate Hydratase / Q000032:analysis; D016708:Synaptophysin / Q000032:analysis; D014057:Tomography, X-Ray Computed; D014617:Vacuoles / Q000648:ultrastructure
D014408:Biomarkers, Tumor; D005904:Glial Fibrillary Acidic Protein; D008055:Lipids; D009363:Neoplasm Proteins; D016708:Synaptophysin; D010751:Phosphopyruvate Hydratase