title: New benzo[5,6]pyrrolizino[1,2-b]quinolines as cytotoxic agents.
abstract: An assessment of structure-activity relationships associated with the new benzo[5,6]pyrrolizino[1,2-b]quinoline system displaying potent in vitro cytotoxic activity against the MCF7 cell line is described.
authors.affiliation: Institut de Chimie Pharmaceutique Albert Lespagnol, EA 2692, Université de Lille, 2, rue du Professeur Laguesse, BP 83, 59006 Lille, France.
authors.forename: Aurore
authors.initials: A
authors.lastname: Perzyna
authors.forename: Frédérique
authors.initials: F
authors.lastname: Klupsch
authors.forename: Raymond
authors.initials: R
authors.lastname: Houssin
authors.forename: Nicole
authors.initials: N
authors.lastname: Pommery
authors.forename: Amélie
authors.initials: A
authors.lastname: Lemoine
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Hénichart
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology*; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D011804:Quinolines / Q000494:pharmacology*
chemical_list: D000970:Antineoplastic Agents; D011804:Quinolines