title: [Efficacy and safety of intraprostatic injection of chuanshentong for chronic abacterial prostatitis/chronic pelvic pain syndrome].
abstract: OBJECTIVE
  To evaluate the efficacy and safety of intraprostatic injection of Chuanshentong in the treatment of chronic abacterial prostatitis/chronic pelvic pain syndrome(CAP/CPPS).
  
  
  METHODS
  Randomized, double blinded, placebo controlled trials were carried out from September 2002 to March 2003. A total of 38 patients with diagnosed CAP/CPPS, 24 experimental and 14 controls, were analyzed. In the trial group, 6 ml of mixed solution of Chuanshentong and lidocaine was transperineally injected into one lobe of the prostate, once a day for 6 days. Likewise, the control group was treated with placebo containing lidocaine. The efficacy was evaluated by the NIH Chronic Prostatitis Symptom Index(CPSI) after a 6-week follow-up. The main semen parameters before and after 3-month treatment were compared.
  
  
  RESULTS
  In the trial group, 13 cases (56.5%) were completely cured, 5 cases(21.7%) showed remarkable effect, and 4 cases (17.4%) were improved. While in the control group, effectiveness was shown in only 2 cases (15.4%), and improvement in 3 cases (23%). CPSI scores decreased significantly after treatment(95% of confidence interval: 17.97-23.08). Chuanshentong solution had no obvious impact on the main semen parameters. No severe adverse effects were observed.
  
  
  CONCLUSIONS
  Transperineal intraprostatic injection of Chuanshentong is a safe and effective method for the treatment of CAP/CPPS.
authors.affiliation: Department of Urology, Guangzhou General Hospital of Guangzhou Command, PLA, Guangzhou, Guangdong 510010, China. urology@sohu.com
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Huixu
authors.initials: H
authors.lastname: He
authors.forename: Weilie
authors.initials: W
authors.lastname: Hu
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Zhang
authors.forename: Yuanli
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000328:Adult; D002908:Chronic Disease; D004311:Double-Blind Method; D004365:Drugs, Chinese Herbal / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D017699:Pelvic Pain / Q000188:drug therapy*; D011472:Prostatitis / Q000188:drug therapy*
chemical_list: D004365:Drugs, Chinese Herbal