[The applied value of rescue intracytoplasmic sperm injection after complete fertilization failure during in vitro fertilization cycles].
OBJECTIVE
To discuss the applied value of rescue intracytoplasmic sperm injection(ICSI) after complete fertilization failure during in vitro fertilization (IVF) cycles.


METHODS
After 16-18 h co-culture with sperm, all the unfertilized oocytes with the first polar body were re-fertilized by ICSI.


RESULTS
After rescue ICSI, the abnormal fertilization rate was 17.9% and the normal fertilization rate was 42.7%. Twenty-four hours later, the normal cleavage rate of the normal fertilized oocytes was 79.6%. On the day of embryo transfer, the good-quality rate of embryos was 29.7% (22/74). A mean number of 3.4 (54/16) embryos were transferred to the patient during each cycle. Clinical pregnancy was found in 3 cases out of the 16 (18.8%).


CONCLUSIONS
The applied value of rescue ICSI may be correlated with the number and maturity of oocytes on the retrieval day.
Feng
Ting
T
Human Clinical Reproductive Medicine Center, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.
Qian
Yun
Y
Liu
Jiayin
J
Mao
Yundong
Y
Chen
Juan
J
Cai
Lingbo
L
D005260:Female; D005306:Fertilization; D005307:Fertilization in Vitro; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D020554:Sperm Injections, Intracytoplasmic