title: Giant neck neoplasm. Case report.
abstract: Giant latero-cervical neoplasias usually originate in the parotid gland, as slow-growing adenomas, in subjects who take little care of their personal health. Giant adenomas of submandibular gland are very rare. These neoplasias involve prevalently male sex (male/female ratio: 2/1) and usually occur between 20 and 40 years of age. Signs of malignant transformation may be observed in the adenomatous epithelial component in a percentage ranging from 1% to 10% of cases. The case is reported of a giant malignant latero-cervical neoplasia originating from a pleomorph adenoma of the submandibular gland. The diagnostic work-up and treatment protocol are described.
authors.affiliation: Otorhinolaringology Unit, 2o Azienda Pisana, Pisa, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Rognini
authors.forename: L
authors.initials: L
authors.lastname: Bruschini
authors.forename: M
authors.initials: M
authors.lastname: Re
authors.forename: P
authors.initials: P
authors.lastname: Bruschini
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D018198:Mixed Tumor, Malignant / Q000473:pathology / Q000601:surgery; D037981:Neck Dissection; D013363:Submandibular Gland / Q000473:pathology; D013365:Submandibular Gland Neoplasms / Q000473:pathology / Q000601:surgery; D013524:Surgical Flaps; D013997:Time Factors; D016896:Treatment Outcome