Prevalence and diversity of Bartonella in rodents of northern Thailand: a comparison with Bartonella in rodents from southern China.
We report results of the first study to investigate the distribution and diversity of Bartonella in rodents from Thailand. Whole blood from 195 rodents, representing six species, was tested for the presence of Bartonella species using standard culture techniques. Isolates were obtained from 17 (8.7%) of the samples, and 14 of those isolates represented distinct strains, based upon partial sequencing of the citrate synthase (gltA) gene. Phylogenetic analysis of the isolates and other Bartonella species indicated that five unique isolates from Bandicota indica form a cluster that may represent a new Bartonella species. Two additional isolates from B. indica clustered together, and were nearly identical to an isolate from Apodemus draco collected in southern China. Importantly, a number of the isolates from Thailand rodents are closely related to B. grahamii and B. elizabethae, species which have been associated with human illness.
Castle
Kevin T
KT
Bacterial Zoonoses Branch, Division of Vector-Borne Infectious Diseases, Centers for Disease Control and Prevention, Foothills Campus, Fort Collins, Colorado 80522, USA. mck3@cdc.gov
Kosoy
Michael
M
Lerdthusnee
Kriangkrai
K
Phelan
Lori
L
Bai
Ying
Y
Gage
Kenneth L
KL
Leepitakrat
Warisa
W
Monkanna
Taweesak
T
Khlaimanee
Nittaya
N
Chandranoi
Kirkvich
K
Jones
James W
JW
Coleman
Russell E
RE
D000818:Animals; D016470:Bacteremia / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary; D001473:Bartonella / Q000235:genetics / Q000254:growth & development*; D001474:Bartonella Infections / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D001483:Base Sequence; D002681:China / Q000453:epidemiology; D002950:Citrate (si)-Synthase / Q000737:chemistry / Q000235:genetics; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D014644:Genetic Variation; D008969:Molecular Sequence Data; D010802:Phylogeny; D016133:Polymerase Chain Reaction / Q000662:veterinary; D015995:Prevalence; D012376:Rodent Diseases / Q000453:epidemiology / Q000382:microbiology*; D012377:Rodentia; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D013785:Thailand / Q000453:epidemiology
D004269:DNA, Bacterial; D002950:Citrate (si)-Synthase