title: [Immunomodulating effect of pyridoxine, folate, and cobalamin in various forms of anemia].
abstract: Hemorrhage and toxic lesions of hemopoietic tissues inhibit the development of various types of immune response and induce immunosuppressive properties in light erythrocytes, while not influencing the immunological activity of heavy erythrocytes. The immunomodulant action of pyridoxine, folate and cobalamin in various cases of anemia was observed for the joint (but not for separate) administration of two vitamin preparations; the most pronounced increase in the immune reactivity taking place upon the joint administration of cobalamin and folate.
authors.affiliation: Department of Sport Medicine, Kursk State Medical University, ul. K. Marksa 3, Kursk, 305033 Russia.
authors.forename: I L
authors.initials: IL
authors.lastname: Brovkina
authors.forename: A A
authors.initials: AA
authors.lastname: Konoplia
authors.forename: B S
authors.initials: BS
authors.lastname: Uteshev
authors.forename: V N
authors.initials: VN
authors.lastname: Rybnikov
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000740:Anemia / Q000188:drug therapy / Q000209:etiology / Q000276:immunology*; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D004359:Drug Therapy, Combination; D005492:Folic Acid / Q000494:pharmacology*; D006968:Hypersensitivity, Delayed / Q000276:immunology; D011736:Pyridoxine / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D014805:Vitamin B 12 / Q000494:pharmacology*
chemical_list: D000276:Adjuvants, Immunologic; D005492:Folic Acid; D011736:Pyridoxine; D014805:Vitamin B 12