title: Manometric evaluation of the intrathoracic stomach after gastric transposition in children.
abstract: Gastric transposition (GT) is one of the options for the esophageal replacement in children with esophageal atresia with or without tracheoesophageal fistula (EATEF). To date, no manometric studies have been conducted on the intrathoracic stomach after GT in EATEF patients; hence, this study was designed. Babies ( n=18) of EATEF who underwent esophageal replacement by GT were studied and manometry was correlated with the clinical outcome, age at surgery, and route of GT. The mean age at evaluation was 30.5 months (range 4-84 months). These cases were sub-stratified into group I (GT during neonatal period) and group II (GT during post-neonatal period). Mean age at surgery was 6 days and 7.8 months in groups I and II, respectively. There was no propulsive antegrade propagated peristaltic waves in any of the patients. Mean resting pressure and mean peak pressures were 19.5 and 50.4 mm Hg in groups I and II, respectively. Mass contractions to liquid swallow was noted in 77 and 55% of patients in groups I and II, respectively. There was no significant difference in the pressure parameters or appearance of mass contractions between group-I and group-II patients. Similarly, there was no significant difference in pressure parameters or appearance of mass contractions between the children who had transhiatal vs retrosternal GT. It needs to be determined whether the mass contractions noted in GT ever progress to a coordinated propulsive rhythmic contractions and whether this has a final bearing on the long-term functional outcome of GT patients.
authors.affiliation: Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi, India. devendra6@hotmail.com
authors.forename: D K
authors.initials: DK
authors.lastname: Gupta
authors.forename: A R
authors.initials: AR
authors.lastname: Charles
authors.forename: M
authors.initials: M
authors.lastname: Srinivas
mesh_terms: D000367:Age Factors; D002675:Child, Preschool; D013505:Digestive System Surgical Procedures; D004933:Esophageal Atresia / Q000601:surgery*; D005769:Gastrointestinal Motility / Q000502:physiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008365:Manometry; D010528:Peristalsis / Q000502:physiology; D011312:Pressure; D013270:Stomach / Q000503:physiopathology* / Q000637:transplantation; D013909:Thorax; D014138:Tracheoesophageal Fistula / Q000601:surgery