[Otomastoiditis candidiasica and hyper IgE syndrome].
A 5-year-old girl presented with chronic otorrhea, cervical adenopathies and cellulitis of the knee. In addition to these lesions, physical examination revealed eczema on the scalp, neck, perineal and umbilical regions and the persistence of deciduous teeth with adult teeth (double dental arch). Complementary investigations showed the following concentrations: IgE 23969 UI/l, IgD 440 U/L, IgG 23000 mg/L, and IgA 4220 mg/L. Intradermal skin testing to Candida was negative and the results of the remaining immunological studies were normal. Computerized axial tomography revealed bilateral otomastoiditis. Candida albicans was isolated from ear secretion cultures. The definitive diagnosis was hyper IgE syndrome. The patient responded favorably to antibiotic and antifungal therapy and is currently undergoing period outpatient monitoring.
Vásquez
C
C
Sección de Alergia e Inmunología Clínica, Unidad Integrada de Pediatría, Hospital Clinic- Hospital Sant Joan de Déu, Universidad de Barcelona, España.
Martín Mateos
M A
MA
Giner
M T
MT
Sierra
J I
JI
Plaza
A M
AM
Díaz
P
P
Jiménez-Feijoo
R
R
D001991:Bronchitis / Q000209:etiology; D002177:Candidiasis / Q000150:complications*; D002181:Candidiasis, Vulvovaginal / Q000150:complications; D002481:Cellulitis / Q000209:etiology; D002675:Child, Preschool; D003817:Dentition; D004198:Disease Susceptibility; D004485:Eczema / Q000209:etiology; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D016867:Immunocompromised Host; D007073:Immunoglobulin E / Q000097:blood*; D008206:Lymphatic Diseases / Q000209:etiology; D008417:Mastoiditis / Q000209:etiology* / Q000382:microbiology; D014009:Onychomycosis / Q000209:etiology; D010034:Otitis Media with Effusion / Q000209:etiology* / Q000382:microbiology; D012008:Recurrence; D013577:Syndrome; D014034:Toes
D007073:Immunoglobulin E