Delayed reactivation of presumed adenoviral subepithelial infiltrates after laser in situ keratomileusis.
OBJECTIVE
To report the reactivation of presumed adenoviral keratitis after laser in situ keratomileusis (LASIK).


METHODS
Case report and literature review.


RESULTS
The patient underwent uneventful LASIK more than 5 years after an episode of adenoviral keratitis that left subepithelial corneal scarring. Three months after LASIK, new subepithelial infiltrates appeared in the right eye. These lesions resolved without sequelae during treatment with topical steroids. The patient's uncorrected and best-corrected visual acuity returned to her postoperative baseline.


CONCLUSIONS
LASIK may cause delayed exacerbation of subepithelial infiltrates caused by adenoviral keratitis. However, good visual outcomes can be achieved with recognition of this reactivation and treatment with topical corticosteroids.
Randleman
J Bradley
JB
Department of Ophthalmology and Emory Vision Refractive Surgery Center, Emory University, Atlanta, GA 30319, USA. jrandle@emory.edu
Hewitt
Susanne M
SM
Stulting
R Doyle
RD
D000258:Adenovirus Infections, Human / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D000260:Adenoviruses, Human / Q000502:physiology*; D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D019573:Epithelium, Corneal / Q000821:virology*; D015828:Eye Infections, Viral / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007634:Keratitis / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D011239:Prednisolone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014775:Virus Activation
D000998:Antiviral Agents; D005938:Glucocorticoids; C009935:prednisolone acetate; D011239:Prednisolone