title: [Genetic risk factors of venous thromboembolism].
abstract: Up to date several hereditary disorders have been identified as prothrombic risk factors. The most common inherited thrombotic disorders include activated protein C resistance (factor V Leiden), prothrombin G20210A mutation, hyperhomocysteinemia, deficiencies of protein C, protein S, antithrombin III, and thrombomodulin. This article focuses on the clinical and the laboratory aspects of some of the inherited venous thrombotic disorders including the factor V Leiden, prothrombin G20210A mutation and protein S deficiency.
authors.affiliation: Ankara University Faculty of Medicine, Pulmonary Diseases, Ankara, Turkey. onerferda@hotmail.com
authors.forename: Ferda
authors.initials: F
authors.lastname: Oner
authors.forename: Akin
authors.initials: A
authors.lastname: Kaya
authors.forename: Ruşina
authors.initials: R
authors.lastname: Doğan
authors.forename: Numan
authors.initials: N
authors.lastname: Numanoğlu
mesh_terms: D000328:Adult; D000368:Aged; D001779:Blood Coagulation Factors / Q000235:genetics*; D005165:Factor V / Q000235:genetics; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008875:Middle Aged; D009154:Mutation; D018455:Protein S Deficiency / Q000235:genetics; D011516:Prothrombin / Q000235:genetics; D012307:Risk Factors; D020246:Venous Thrombosis / Q000175:diagnosis / Q000235:genetics*
chemical_list: D001779:Blood Coagulation Factors; C095381:factor V Leiden; D005165:Factor V; D011516:Prothrombin