title: Assessment of left ventricular function in healthy subjects by pusled wave Doppler tissue imaging.
abstract: OBJECTIVE
  To examine the clinical application of pulsed Doppler tissue imaging (DTI) for regional left ventricular function assessment in normal subjects.
  
  
  METHODS
  We examined 50 healthy subjects (range 12-42 years, mean age 28.3 +/- 6.9 years) using pulsed Doppler tissue imaging to characterize the diastolic and systolic velocity profiles of mitral annulus. Recordings were made along the long axis in the apical 4-chamber, 2-chamber, and long apical views of 6 sites (posterior-septum, lateral, anterior, inferior, anterior-septum, posterior) at the mitral annulus. Myocardial velocities were determined with use of variance F statistical analysis. Correlation analysis was employed to test the relationship between age and mitral annular velocities.
  
  
  RESULTS
  Both early diastolic and systolic velocities at the septum were lower than other sites. There were no differences in mitral annulus late diastolic velocities. Mean early diastolic and systolic velocities was negatively correlated with age.
  
  
  CONCLUSIONS
  Doppler tissue imaging can directly reflect regional left ventricular function.
authors.affiliation: Department of Ultrasound, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100037. Leejingabc@sina.com
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Yanling
authors.initials: Y
authors.lastname: Liu
authors.forename: Hao
authors.initials: H
authors.lastname: Wang
authors.forename: Xiuzhang
authors.initials: X
authors.lastname: Lu
authors.forename: Fujian
authors.initials: F
authors.lastname: Duan
authors.forename: Hongchang
authors.initials: H
authors.lastname: Yang
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001783:Blood Flow Velocity; D002648:Child; D003971:Diastole; D018619:Echocardiography, Doppler, Pulsed / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000000981:diagnostic imaging* / Q000502:physiology; D012016:Reference Values; D013599:Systole; D016277:Ventricular Function, Left