title: [The microecological disorders in clinical pathology and their correction by bifidum-containing probiotics].
abstract: On the basis of independent research and published data surveyed in the paper is the prevalence and nature of disorders of the intestinal microflora observed in adults and children with different pathologies, i.e. chronic diseases of the gastrointestinal tract, acute intestinal infections, acute respiratory viral infections, pneumonias, as well as certain nephrological, gynecological, and surgical diseases etc. The deficit of Bifidobacteria was found to be the most frequent chain in intestinal microflora pathologies. The significance of Bifido-containing drugs as well as current research of Russian scientists, including new probiotics with Bifidobacteria immobilized in coal, is elucidated. The advantages of intestinal dysbacteriosis correction by sorbated Bifido-containing probiotics, like bifidumbacterin forte and probifor, are demonstrated, versus bifidumbacterin, in different pathologies; their related clinical-and-morphological effect is defined. Prospects for designing the combined and polyvalent drugs with immobilized Bifidobacteria are described.
authors.forename: A A
authors.initials: AA
authors.lastname: Vorob'ev
authors.forename: V M
authors.initials: VM
authors.lastname: Bondarenko
authors.forename: E A
authors.initials: EA
authors.lastname: Lykova
authors.forename: A V
authors.initials: AV
authors.lastname: Grigor'ev
authors.forename: T M
authors.initials: TM
authors.lastname: Matsulevich
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000382:microbiology / Q000628:therapy*; D001644:Bifidobacterium / Q000302:isolation & purification; D001688:Biological Products / Q000627:therapeutic use; D002648:Child; D006801:Humans; D007410:Intestinal Diseases / Q000382:microbiology / Q000628:therapy*; D007422:Intestines / Q000382:microbiology*; D019936:Probiotics / Q000627:therapeutic use*; D012140:Respiratory Tract Diseases / Q000382:microbiology / Q000628:therapy*
chemical_list: D000890:Anti-Infective Agents; D001688:Biological Products; C010546:bifidobacterin