title: Use of complementary medicines for osteoarthritis--a prospective study.
abstract: BACKGROUND
  Patients with osteoarthritis commonly use complementary and alternative medicines (CAM), either as an adjunct to or in place of conventional analgesics.
  
  
  OBJECTIVE
  To undertake a prospective investigation of the prevalence of CAM use for osteoarthritis and the direct costs incurred.
  
  
  METHODS
  The subjects were 341 patients with osteoarthritis of the knee or hip drawn from central and northern Sydney, Australia, and comprising 83 community based patients and 258 awaiting joint replacement. Information on CAM use was obtained from prospective three monthly diaries. Variables of interest included health related quality of life scores. Prospective out of pocket costs were recorded over a 12 month follow up period.
  
  
  RESULTS
  The prevalence of CAM use was 40%, which falls within the range of previous studies. Average annual expenditure on CAM was 32.25 Australian dollars (range 0 to 603.30). CAM users were more likely to be female (odds ratio (OR) 1.8 (95% confidence interval, 1.1 to 3.0)), reported a higher level of bodily pain (OR 0.97 (0.95 to 0.99)), and were less likely to purchase conventional analgesics (OR 3.3 (1.6 to 7.0)), either prescribed or over the counter. Vitamin supplementation was the most common CAM reported, followed by celery extract, fish oils, and garlic extracts.
  
  
  CONCLUSIONS
  There are no good quality clinical trials to support the use of most preparations purchased by patients with osteoarthritis. There is a need for patient education on the risks and benefits of complementary medicine in osteoarthritis.
authors.affiliation: Institute of Bone and Joint Research, University of Sydney, Australia. jzochlin@med.usyd.edu.au
authors.forename: J
authors.initials: J
authors.lastname: Zochling
authors.forename: L
authors.initials: L
authors.lastname: March
authors.forename: H
authors.initials: H
authors.lastname: Lapsley
authors.forename: M
authors.initials: M
authors.lastname: Cross
authors.forename: K
authors.initials: K
authors.lastname: Tribe
authors.forename: P
authors.initials: P
authors.lastname: Brooks
mesh_terms: D000368:Aged; D015331:Cohort Studies; D000529:Complementary Therapies / Q000191:economics / Q000706:statistics & numerical data*; D003365:Costs and Cost Analysis; D005260:Female; D006801:Humans; D008297:Male; D015207:Osteoarthritis, Hip / Q000191:economics / Q000628:therapy*; D020370:Osteoarthritis, Knee / Q000191:economics / Q000628:therapy*; D011446:Prospective Studies; D012044:Regression Analysis