[Hypertrophic cardiomyopathy associated with oral corticosteroid therapy for palpebral hemangioma].
BACKGROUND
Systemic corticosteroid therapy is the usual treatment for hemangioma with vascular risk. Tolerance to such treatment is usually good.


METHODS
A two Month-old girl presented with a hemangioma of the lower right eyelid that had developed since she was 15 days old. Treatment with betamethasone at the dose of 0.3 mg/kg/day was prescribed because of the risk of alteration in sight. The treatment was highly effective. The discovery of a systolic cardiac murmur motivated a cardiac sonography that showed signs of an obstructive hypertrophic myocardiopathy. The progressive reduction of the corticosteroids led to the regression of this disease.


CONCLUSIONS
The onset of a cardiomyopathy during systemic corticosteroid therapy has only been reported exceptionally in the literature. There is little known of the risks. When in doubt, clinical and sonographic monitoring is probably necessary. In the case of the appearance of a cardiac murmur, the sonography is crucial.
Some Nina
K
K
Service de Dermatologie, CHU, Tours.
Lorette
G
G
Chantepie
A
A
Villerette
C
C
Machet
L
L
D000284:Administration, Oral; D001623:Betamethasone / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D002312:Cardiomyopathy, Hypertrophic / Q000139:chemically induced*; D005142:Eyelid Neoplasms / Q000188:drug therapy*; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D006337:Heart Murmurs / Q000139:chemically induced; D006391:Hemangioma / Q000188:drug therapy*; D006801:Humans; D007223:Infant
D005938:Glucocorticoids; D001623:Betamethasone