title: Unruptured intracranial aneurysm as a cause of focal epilepsy: an excellent postoperative outcome after intra-arterial treatment.
abstract: This report involves a patient suffering from focal epilepsy caused by an unruptured, intracranial aneurysm (UIA), and her treatment using intravascular embolisation, with an excellent postoperative outcome in terms of the epilepsy. A 52 year-old, right-handed woman had been suffering for three years from focal seizures, characterized by loss of consciousness, and oroalimentary and hand automatisms. The epilepsy was not controlled by carbamazepine monotherapy. Magnetic resonance imaging and digital subtraction angiography revealed a saccular aneurysm at the bifurcation of the middle cerebral artery, in contact with the cortex of the temporal opercular region. An intra-arterial embolisation, using a detachable, mechanical spiral (MDS, Bold Platinum), was performed, with no complications. The purpose of embolisation was the treatment of the aneurysm. The patient had two more, complex partial seizures (CPS) in the early postoperative period, but was seizure-free between September 1998 and September 2002. This is the first case report that presents the successful treatment of UIA-related epilepsy by means of intravascular embolisation.
authors.affiliation: Department of Neurology, Brno Epilepsy Centre, Masaryk University, St Anneís Hospital, Brno, Czech Republic. robert.kuba@fnusa.cz
authors.forename: Robert
authors.initials: R
authors.lastname: Kuba
authors.forename: Petr
authors.initials: P
authors.lastname: Krupa
authors.forename: Lenka
authors.initials: L
authors.lastname: Okacova
authors.forename: Ivan
authors.initials: I
authors.lastname: Rektor
mesh_terms: D002533:Cerebral Angiography; D004621:Embolization, Therapeutic; D017029:Epilepsy, Complex Partial / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D013382:Subtraction Technique; D016896:Treatment Outcome