title: [Developmental characteristics of the sensorimotor cortex of 7-8 days old rats in the roller cultures of free-floating brain slices].
abstract: Development and formation of neuronal architectonic of organotypic structures of sensomotor cortex of 7-8-day-old rats was studied in roller cultures. Free-floating cortical slices were cultured for 2-3 weeks. Serial paraffin sections of cultured tissue were stained with cresyl violet fast using Nissl's method. It was shown that during cultivation cortical slices changed their initial flat configuration and transformed into spherical bodies that retained main histiotypic features of cortical formations. Radially oriented pyramidal and fusiform neurons formed cortical structure that was not subdivided into individual layers and covered the whole surface of spherical tissue bodies. It is concluded that histogenetical processes were continuing in free-floating slices of sensomotor cortex of 7-8-day-old rats during roller cultivation. They result in formation of histiotypic cortical structure similar to phylogenetically more ancient allocortical formations of the forebrain.
authors.affiliation: Laboratory of Experimental Neurocytology, RAMS Brain Research Insitute, Moscow.
authors.forename: O P
authors.initials: OP
authors.lastname: Aleksandrova
authors.forename: A A
authors.initials: AA
authors.lastname: Lyzhin
authors.forename: I V
authors.initials: IV
authors.lastname: Viktorov
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002454:Cell Differentiation / Q000502:physiology*; D006652:Histological Techniques / Q000379:methods; D009044:Motor Cortex / Q000166:cytology / Q000254:growth & development*; D009474:Neurons / Q000166:cytology*; D009924:Organ Culture Techniques; D051381:Rats; D013003:Somatosensory Cortex / Q000166:cytology / Q000254:growth & development*