Mass spectral fragmentation of 2a,4-disubstituted 2,2a,3,4-tetrahydro-2-phenoxy-1H-azeto[2,1-d][1,5]benzothiazepin-1-ones under electron impact ionization conditions.
The mass spectrometric fragmentation of 2a,4-disubstituted 2,2a,3,4-tetrahydro-2-phenoxy-1H-azeto[2,1-d][1,5]benzothiazepin-1-ones has been investigated using the aid of mass-analyzed ion kinetic energy spectrometry. All compounds tend to eliminate a phenoxy, phenol, and phenoxyketene, respectively, from molecular ions. [M(+)-PhO] ions could also form [M(+)-PhOH] ions, which could further lose alkenes. [M(+)-PhOCH=C=O] ions could further yield 2-arylbenzothiazole ions and other fragment ions.
Xu
Jiaxi
J
Department of Chemical Biology, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. jxxu@chem.pku.edu.cn
Huang
Xu
X
D000929:Antidepressive Agents, Tricyclic / Q000138:chemical synthesis / Q000737:chemistry*; D001569:Benzodiazepines / Q000138:chemical synthesis / Q000737:chemistry*; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis / Q000737:chemistry; D013058:Mass Spectrometry / Q000379:methods*; D015394:Molecular Structure
D000929:Antidepressive Agents, Tricyclic; D006575:Heterocyclic Compounds, 3-Ring; D001569:Benzodiazepines