title: Eosinophilic angiocentric fibrosis in a patient with nasal obstruction.
abstract: Eosinophilic angiocentric fibrosis (EAF) is a rare clinicopathologic entity that usually affects the upper respiratory tract. We describe the case of a 45-year-old man with nasal obstruction caused by EAF. His lesion featured the distinct radiologic and histopathologic characteristics of EAF, which include an onionskin and whorled fibrosis that surrounds the blood vessels and an inflammatory infiltrate that is predominated by eosinophils. The etiology of EAF remains unknown. Given our increasing knowledge of this rare entity, reports of EAF may appear more frequently in the future.
authors.affiliation: Division of Facial Plastic and Reconstructive Surgery, Section of Otolaryngology, Yale University School of Medicine, New Haven, Conn 06520, USA. davisbnguyen@aol.com
authors.forename: Davis B
authors.initials: DB
authors.lastname: Nguyen
authors.forename: James C
authors.initials: JC
authors.lastname: Alex
authors.forename: Benjamin
authors.initials: B
authors.lastname: Calhoun
mesh_terms: D004802:Eosinophilia / Q000150:complications / Q000473:pathology*; D005355:Fibrosis / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D015508:Nasal Obstruction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D014057:Tomography, X-Ray Computed