title: High prevalence of the hepatitis C virus infection among the inpatients of schizophrenia and psychoactive substance abuse in Japan.
abstract: Prevalence of anti-HCV antibody in 1193 hospitalized patients (848 males and 345 females) in psychiatric department was investigated. Overall prevalence ratio was 9.1%, indicating significantly higher than that of healthy blood donors. In the classification of ICD-10, the prevalence of the inpatients diagnosed in schizophrenia group and psychoactive substance use group accounted for 6.2% and 13.8%, respectively. However, adequate reasons such as sanitary issues were not found to account for the high prevalence. Only the age of the patients could account for the high prevalence in the schizophrenic group. In the psychoactive substance abuse group, the sanitary issues might be a major cause of the very high prevalence of anti-HCV antibody, while other factors such as dysfunction of the immune system might be considered to account for it.
authors.affiliation: Department of Psychiatry, Nara Medical University, 840 Shijio-cho, Kashihara, Nara 634-8521, Japan. yunaka@naramed-u.ac.jp
authors.forename: Yu
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Motoasa
authors.initials: M
authors.lastname: Koh
authors.forename: Eiji
authors.initials: E
authors.lastname: Miyoshi
authors.forename: Osamu
authors.initials: O
authors.lastname: Ida
authors.forename: Masayuki
authors.initials: M
authors.lastname: Morikawa
authors.forename: Akihiro
authors.initials: A
authors.lastname: Tokuyama
authors.forename: Tatsuji
authors.initials: T
authors.lastname: Nagano
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Honda
authors.forename: Junzo
authors.initials: J
authors.lastname: Iida
authors.forename: Kunya
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Naoki
authors.initials: N
authors.lastname: Minami
authors.forename: Akinori
authors.initials: A
authors.lastname: Kasahara
authors.forename: Motoharu
authors.initials: M
authors.lastname: Hirai
authors.forename: Norio
authors.initials: N
authors.lastname: Hayashi
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Kishimoto
mesh_terms: D000328:Adult; D000367:Age Factors; D000437:Alcoholism / Q000150:complications / Q000453:epidemiology; D019969:Amphetamine-Related Disorders / Q000150:complications / Q000453:epidemiology; D001782:Blood Donors / Q000706:statistics & numerical data; D005260:Female; D006526:Hepatitis C / Q000150:complications* / Q000453:epidemiology*; D018937:Hepatitis C Antibodies / Q000032:analysis; D006801:Humans; D007297:Inpatients; D007564:Japan / Q000453:epidemiology; D008297:Male; D012559:Schizophrenia / Q000150:complications* / Q000453:epidemiology*; D012727:Sex Characteristics; D019966:Substance-Related Disorders / Q000150:complications* / Q000453:epidemiology*
chemical_list: D018937:Hepatitis C Antibodies