title: Renal dysplasia and urinary tract infection in a Bull Mastiff puppy.
abstract: Renal dysplasia and concurrent pyelonephritis were diagnosed in a 15-week-old female Bull Mastiff which presented with clinical signs compatible with chronic renal failure. Ultrasound examination was consistent with renal dysplasia and clinical pathology supported a diagnosis of chronic renal failure and urinary tract infection. Renal histological examination demonstrated inflammation and scarring with concurrent tubular dysplasia and persisting primitive glomeruli, although the presence of chronic inflammation complicated interpretation. It is uncertain whether renal dysplasia was inherited or due to a urinary tract infection acquired in the neonatal period. Renal dysplasia has not previously been reported in the Bull Mastiff breed.
authors.affiliation: University of Melbourne, Department of Veterinary Science, 250 Princes Highway, Werribee, Victoria 3030.
authors.forename: L A
authors.initials: LA
authors.lastname: Abraham
authors.forename: C
authors.initials: C
authors.lastname: Beck
authors.forename: R F
authors.initials: RF
authors.lastname: Slocombe
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001774:Blood Chemical Analysis / Q000662:veterinary; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics; D004285:Dogs; D005260:Female; D007668:Kidney / Q000002:abnormalities*; D007676:Kidney Failure, Chronic / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D014463:Ultrasonography; D014552:Urinary Tract Infections / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*