A plug and play microfluidic device.
Chip-to-world interface is a major issue in the field of microfluidics and its applications. We developed a plug and play microfluidic device composed of a fluid driving unit and a polymer chip containing microfluidic channels and reservoirs. The one and only connection of the device to the external world is a set of electric control lines for the driving unit. Just putting the reagents and samples onto the reservoirs, the chip can be operated for chemical or biochemical reaction and analysis. We demonstrate here that silicon-based micropumps embedded in the present device allow us to achieve flexible fluidic manipulations with minimum time delay and dead volume.
Fujii
Teruo
T
Institute of Industrial Science, University of Tokyo, 4-6-1 Komaba Meguro-ku, Tokyo 153-8505, Japan. tfujii@iis.u-tokyo.ac.jp
Sando
Yasuhiro
Y
Higashino
Kusunoki
K
Fujii
Yasuhisa
Y
D000818:Animals; D004058:Diffusion; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D004581:Electronics; D004867:Equipment Design; D049454:Firefly Luciferin / Q000378:metabolism; D007700:Kinetics; D008156:Luciferases / Q000378:metabolism; D008163:Luminescent Measurements; D044085:Microfluidics / Q000295:instrumentation* / Q000379:methods; D012828:Silicones / Q000737:chemistry
D004129:Dimethylpolysiloxanes; D012828:Silicones; D049454:Firefly Luciferin; C013830:baysilon; D008156:Luciferases