Potentiometric titrations in a poly(dimethylsiloxane)-based microfluidic device.
This paper describes a microfluidic device, fabricated in poly(dimethylsiloxane), that is used for potentiometric titrations. This system generates step gradients of redox potentials in a series of microchannels. These potentials are probed by microelectrodes that are integrated into the chip; the measured potentials were used to produce a titration curve from which the end point of a reaction was measured.
Ferrigno
Rosaria
R
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
Lee
Jessamine Ng
JN
Jiang
Xingyu
X
Whitesides
George M
GM
D004129:Dimethylpolysiloxanes / Q000737:chemistry*; D004566:Electrodes; D044085:Microfluidics / Q000295:instrumentation / Q000379:methods*; D010984:Platinum / Q000737:chemistry; D011199:Potentiometry / Q000379:methods; D012828:Silicones / Q000737:chemistry*
D004129:Dimethylpolysiloxanes; D012828:Silicones; D010984:Platinum; C013830:baysilon