[Anti-inflammatory effect of arglabin and 11,13-dihydro-13-dimethylaminoarglabin hydrochloride].
The sesquiterpene lactone arglabin, as well as its derivative 11,13-Dihydro-13-dimethylaminoarglabin hydrochloride, exhibit antiexudative and antiproliferative properties on the models of acute aseptic inflammation caused by formalin, carrageenan, and histamine, and on the model of proliferative inflammation accompanying cotton-pellet granuloma.
Abil'daeva
A Zh
AZh
Laboratory of Phytopreparation Technology and Pharmacology, Institute of Phytochemistry, ul. Gazalieva 4, Karaganda, 470032 Kazakhstan.
Pak
R N
RN
Kulyiasov
A T
AT
Adekenov
S M
SM
D000208:Acute Disease; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use; D007249:Inflammation / Q000188:drug therapy / Q000209:etiology; D007783:Lactones / Q000627:therapeutic use*; D008297:Male; D051381:Rats; D012717:Sesquiterpenes / Q000627:therapeutic use*; D045789:Sesquiterpenes, Guaiane
C487619:11,13-dihydro-13-dimethylaminoarglabin hydrochloride; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000970:Antineoplastic Agents; D007783:Lactones; D012717:Sesquiterpenes; D045789:Sesquiterpenes, Guaiane; C083346:arglabin