[Prophylaxis of respiratory infections outbreaks with dipyridamol in young servicemen].
The purpose of investigation was to evaluate the efficiency and safety of dipyridamole (the inductor of endogenous interferon) in prevention of outbreaks of extrahospital pneumonia (EP) and acute respiratory diseases (ARD). 2226 servicemen arrived to the educational center were studied. In the control group (n = 1034) EP developed in 11.9%, clinically significant ARD cases were noted in 18.7% (in prophylaxis group 9.6 and 11.7% respectively). The efficiency and safety of dipyridamole used to prevent ARD was demonstrated.
Klochkov
O I
OI
Guchev
I A
IA
D000293:Adolescent; D000328:Adult; D004176:Dipyridamole / Q000008:administration & dosage / Q000627:therapeutic use*; D004196:Disease Outbreaks / Q000517:prevention & control*; D006801:Humans; D007369:Interferon Inducers / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008889:Military Personnel; D011446:Prospective Studies; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D012426:Russia; D012621:Seasons; D014777:Virus Diseases / Q000150:complications / Q000453:epidemiology
D007369:Interferon Inducers; D004176:Dipyridamole