title: [Adverse effects of continuous positive airway pressure therapy and its relation to the nose].
abstract: The main problem in the treatment of obstructive sleep apnea syndrome (OSAS) with nasal continuous airway pressure (nCPAP) is the lack of compliance. One of the most important reasons for no compliance is the adverse effects of this treatment. We analyse, prospectively, 182 patients treated with nCPAP in order to show the relationship between previous nasal problems and adverse effects of nCPAP. Sixty percent of the population developed one o more side effects. Of this group, 69% showed nasal septum deviation at first examination in front of 31% that did not showed this problem (p = 0.001). In the group of patients with nasal side effects we observed an increase of compliance in 80% of patients treated medically and in 89% of those treated by a septoplasty. We demonstrate that the adverse effects of nCPAP are related to previous nasal problems and, also, that treatment of those problems can achieve an increase in compliance to nCPAP therapy.
authors.affiliation: Servicio de Otorrinolaringología, Hospital General de Catalunya, 08190 Sant Cugat del Valles, Barcelona.
authors.forename: E
authors.initials: E
authors.lastname: Esteller
authors.forename: E
authors.initials: E
authors.lastname: Matiñó
authors.forename: F
authors.initials: F
authors.lastname: Segarra
authors.forename: J J
authors.initials: JJ
authors.lastname: Sanz
authors.forename: J M
authors.initials: JM
authors.lastname: Ademà
authors.forename: E
authors.initials: E
authors.lastname: Estivill
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009668:Nose Diseases / Q000209:etiology*; D011175:Positive-Pressure Respiration / Q000009:adverse effects*; D011446:Prospective Studies; D020181:Sleep Apnea, Obstructive / Q000628:therapy*