title: A comparison of prognoses of FIGO stage IB adenocarcinoma and squamous cell carcinoma.
abstract: OBJECTIVE
  The objective of this study was to compare clinical and pathologic variables and prognosis of FIGO stage IB adenocarcinoma and squamous cell carcinoma of uterine cervix.
  
  
  METHODS
  A retrospective review was performed of 521 patients with stage IB squamous cell carcinoma and adenocarcinoma of cervix who treated primarily by type 3 hysterectomy and pelvic and/or para-aortic lymphadenectomy at Hacettepe University Hospitals between 1980 and 1997.
  
  
  RESULTS
  Age, tumor size, grade, depth of invasion, lymph node metastasis, parametrial, vaginal, and lymphvascular space involvement (LVSI) were not different between two cell types except number of the lymph nodes involved. Metastasis to three or more lymph nodes was significantly higher in adenocarcinoma. Overall and disease-free survival were 87.7%, 84.0% versus 86.4%, 83.1% for squamous cell carcinoma and adenocarcinoma, respectively (P > 0.05). The rate and site of recurrence were not different between two cell types. Multivariate analysis of disease-free and overall survival revealed independent prognostic factors as tumor size, LVSI, number of involved lymph node, and vaginal involvement.
  
  
  CONCLUSIONS
  Prognosis of FIGO stage IB cervical cancer patients who were treated by primarily radical surgery was found to be same for those with adenocarcinoma and squamous cell carcinoma.
authors.affiliation: Department of Obstetrics and Gynecology, Gynecologic Oncology Unit, Hacettepe University School of Medicine, Hacettepe University Hospitals, 06100 Sihhye, Ankara, Turkey. cem.baykal@ttnet.net.tr
authors.forename: A
authors.initials: A
authors.lastname: Ayhan
authors.forename: R A
authors.initials: RA
authors.lastname: Al
authors.forename: C
authors.initials: C
authors.lastname: Baykal
authors.forename: E
authors.initials: E
authors.lastname: Demirtas
authors.forename: K
authors.initials: K
authors.lastname: Yüce
authors.forename: A
authors.initials: A
authors.lastname: Ayhan
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008499:Medical Records; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D016019:Survival Analysis; D014421:Turkey / Q000453:epidemiology; D014594:Uterine Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery