Dapsone-induced hypersensitivity pneumonitis mimicking Pneumocystis carinii pneumonia in a patient with AIDS.
Interstitial pneumonitis, often related to infectious etiologies, occurs commonly in HIV-infected patients. However, hypersensitivity pneumonitis from noninfectious etiologies, including environmental stimuli or drug exposure, is an unusual etiology of interstitial pneumonitis in HIV-infected patients. We report a patient with AIDS who developed a dapsone-induced hypersensitivity pneumonitis mimicking Pneumocystis carinii (PCP) pneumonia. We believe drug-induced hypersensitivity pneumonitis should be considered in the differential diagnosis of interstitial pneumonia in HIV-infected patients in whom infectious etiologies have been ruled out.
Tobin-D'Angelo
Melissa J
MJ
Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Hoteit
Maarouf A
MA
Brown
Katia V
KV
Ray
Susan M
SM
King
Mark D
MD
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000542:Alveolitis, Extrinsic Allergic / Q000139:chemically induced* / Q000175:diagnosis; D003622:Dapsone / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D011020:Pneumonia, Pneumocystis / Q000175:diagnosis*
D003622:Dapsone