title: [Studies on the antigens of invasive stages of Plasmodium yoelii and Plasmodium berghei].
abstract: OBJECTIVE
  To detect the rhoptry and surface proteins of invasive stages of Plasmodium yoelii and P. berghei with monoclonal antibodies.
  
  
  METHODS
  Subcellular localization of antigens was detected by IFA. The antigens of different stages of the two species malaria parasites were analyzed by Western blotting.
  
  
  RESULTS
  The antigens of rhoptry are very complicated. There are similar epitopes of the rhoptry proteins detected between the two species of Plasmodium. The similar epitopes were also detected between ookinetes and merozoites of P. yoelii, and ookinete antigens between the two species. But there are different antigens detected between merozoites and ookinetes in P. yoelii. The sporozoite surface antigen of P. yoelii was not detected in the ookinetes and merozoites in the same species.
  
  
  CONCLUSIONS
  There are similar epitopes in the rhoptry and surface antigens of different stages and different species of rodent malaria parasites. There are also distinct antigens among them.
authors.affiliation: Department of Parasitology, Shantou University Medical College, Shantou 515031.
authors.forename: Li-qun
authors.initials: LQ
authors.lastname: Jin
authors.forename: Jian-min
authors.initials: JM
authors.lastname: Luo
authors.forename: Yu-cai
authors.initials: YC
authors.lastname: Fu
authors.forename: Shi-e
authors.initials: SE
authors.lastname: Xu
authors.forename: Yan
authors.initials: Y
authors.lastname: Guo
authors.forename: Lin-chong
authors.initials: LC
authors.lastname: Xie
authors.forename: T
authors.initials: T
authors.lastname: Tsuboi
authors.forename: M
authors.initials: M
authors.lastname: Torii
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D000953:Antigens, Protozoan / Q000032:analysis* / Q000737:chemistry / Q000276:immunology; D000954:Antigens, Surface / Q000032:analysis* / Q000737:chemistry / Q000276:immunology; D015153:Blotting, Western; D000939:Epitopes / Q000276:immunology; D019084:Fluorescent Antibody Technique, Indirect; D051379:Mice; D010962:Plasmodium berghei / Q000276:immunology*; D010967:Plasmodium yoelii / Q000276:immunology*; D015800:Protozoan Proteins / Q000032:analysis* / Q000737:chemistry / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D000953:Antigens, Protozoan; D000954:Antigens, Surface; D000939:Epitopes; D015800:Protozoan Proteins; C065352:rhoptry associated protein, Plasmodium