title: Linear IgA disease presenting as desquamative gingivitis: a pattern poorly recognized in medicine.
abstract: Linear IgA disease is a subepidermal blistering disorder of unknown cause. Along with dermatologic blistering, other manifestations include oral ulceration and desquamative gingivitis. We present a case of linear IgA disease that manifested simply as oropharyngeal ulceration and desquamative gingivitis, resulting in considerable delay in diagnosis and treatment. This article (1) highlights the difficulties of diagnosing linear IgA disease when the predominant presenting features are mucosal and (2) reviews the current literature regarding linear IgA disease.
authors.affiliation: Department of Oral Surgery, Oral Medicine, and Oral Pathology, Dublin Dental School and Hospital, Ireland.
authors.forename: Esther
authors.initials: E
authors.lastname: O'Regan
authors.forename: Anita
authors.initials: A
authors.lastname: Bane
authors.forename: Stephen
authors.initials: S
authors.lastname: Flint
authors.forename: Conrad
authors.initials: C
authors.lastname: Timon
authors.forename: Mary
authors.initials: M
authors.lastname: Toner
mesh_terms: D001327:Autoimmune Diseases / Q000276:immunology / Q000473:pathology*; D001485:Basement Membrane / Q000276:immunology / Q000473:pathology; D001706:Biopsy; D003937:Diagnosis, Differential; D019084:Fluorescent Antibody Technique, Indirect; D005881:Gingiva / Q000473:pathology; D005891:Gingivitis / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000276:immunology / Q000473:pathology; D019226:Oral Ulcer / Q000276:immunology / Q000473:pathology*
chemical_list: D007070:Immunoglobulin A