title: Effectiveness of intensive rehabilitation on functional ability and quality of life after first total knee arthroplasty: A single-blind randomized controlled trial.
abstract: OBJECTIVE
  To evaluate the effectiveness of a new intensive functional rehabilitation (IFR) program on functional ability and quality of life (QOL) in persons who underwent a first total knee arthroplasty (TKA).
  
  
  METHODS
  Randomized controlled trial.
  
  
  METHODS
  Ambulatory care.
  
  
  METHODS
  Seventy-seven people with knee osteoarthritis.
  
  
  METHODS
  Two months after TKA, subjects were randomly assigned to either a group with IFR (n=38), who received 12 supervised rehabilitation sessions combined with exercises at home between months 2 and 4 after TKA, or to a control group (n=39), who received standard care. All participants were evaluated by a blind evaluator at baseline (2mo after TKA), immediately after IFR (2mo later; POST1), and 2 and 8 months later (POST2 and POST3). Main outcome measures The primary outcome measure with respect to effectiveness was the 6-minute walk test (6MWT) at POST2. Secondary outcome measures were the 6MWT at the other evaluations and the Western Ontario and McMaster Universities Osteoarthritis Index and Medical Outcomes Study 36-Item Short-Form Health Survey.
  
  
  RESULTS
  Subjects in the IFR group walked longer distances (range, 23-26m) in 6 minutes at the 3 POST evaluations than subjects in the control group. At POST1 and POST2, they also had less pain, stiffness, and difficulty in performing daily activities. Positive changes in QOL in favor of the IFR were found only at POST2.
  
  
  CONCLUSIONS
  The IFR was effective in improving the short-term and mid-term functional ability after uncomplicated primary TKA. The magnitude of the IFR effect on the primary outcome was modest but consistent. More intensive rehabilitation should be promoted in the subacute recovery period after TKA, to optimize functional outcomes in the first year after surgery.
authors.affiliation: Department of Rehabilitation, Laval University, Quebec City, Canada. helene.moffet@rea.ulaval.ca
authors.forename: Hélène
authors.initials: H
authors.lastname: Moffet
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Collet
authors.forename: Stanley H
authors.initials: SH
authors.lastname: Shapiro
authors.forename: Gaston
authors.initials: G
authors.lastname: Paradis
authors.forename: François
authors.initials: F
authors.lastname: Marquis
authors.forename: Lucille
authors.initials: L
authors.lastname: Roy
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee / Q000534:rehabilitation*; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery; D011788:Quality of Life; D016896:Treatment Outcome