title: Bilateral deep keratitis caused by systemic lupus erythematosus.
abstract: We report the optical and ultrasonic biomicroscopy and confocal microscopy findings in bilateral stromal keratitis (keratoendotheliitis), a rare ocular manifestation of systemic lupus erythematosus (SLE). Examination revealed deposits with polyrefringent crystals. Topical corticosteroid produced regression of the corneal edema, but there was an increase in corneal opacity. Ultrasound biomicroscopy images confirmed the deep location of the corneal opacities, and confocal microscopy showed a disruption of the corneal stroma and crystal-like bodies.
authors.affiliation: Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil.
authors.forename: Consuelo B D
authors.initials: CB
authors.lastname: Adan
authors.forename: Virgínia F M
authors.initials: VF
authors.lastname: Trevisani
authors.forename: Mônica
authors.initials: M
authors.lastname: Vasconcellos
authors.forename: Denise
authors.initials: D
authors.lastname: de Freitas
authors.forename: Luciene B
authors.initials: LB
authors.lastname: de Souza
authors.forename: Mark
authors.initials: M
authors.lastname: Mannis
mesh_terms: D000328:Adult; D015715:Corneal Edema / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D003318:Corneal Opacity / Q000000981:diagnostic imaging / Q000209:etiology; D003319:Corneal Stroma / Q000473:pathology*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007634:Keratitis / Q000175:diagnosis / Q000209:etiology*; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D018613:Microscopy, Confocal; D014463:Ultrasonography
chemical_list: D005938:Glucocorticoids