Renal subcapsular hematoma associated with brodifacoum toxicosis in a dog.
A 5-y-old female dog died acutely and was presented for postmortem examination. Hemorrhage in the thoracic and peritoneal cavities and a large subcapsular renal hematoma were present at necropsy. Brodifacoum, a second-generation coumarin anticoagulant, was detected in the liver by HPLC analysis. Renal subcapsular hematoma is a well known, but uncommon condition in man. To the authors' knowledge, this is the first report of a brodifacoum-associated renal subcapsular hematoma in a non-human species.
Radi
Zaher A
ZA
Tifton Diagnostic and Investigational Laboratory, The University of Georgia, PO Box 1389, Tifton, GA 31793-1389, USA.
Thompson
Larry J
LJ
D015110:4-Hydroxycoumarins / Q000506:poisoning*; D000818:Animals; D000925:Anticoagulants / Q000506:poisoning*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000139:chemically induced / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D005260:Female; D006406:Hematoma / Q000139:chemically induced / Q000175:diagnosis / Q000662:veterinary*; D007674:Kidney Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000662:veterinary*; D011041:Poisoning / Q000175:diagnosis / Q000662:veterinary*
D015110:4-Hydroxycoumarins; D000925:Anticoagulants; C013418:bromfenacoum