title: Continuous wear silicone hydrogel contact lenses and microbial keratitis.
abstract: Like other lens types, the new generation of silicone hydrogel contact lenses can be associated with a spectrum of ocular complications. Most tend to be very minor, but serious and sight-threatening complications can occur. We present four such cases with microbial keratitis following extended wear of these lenses. Cultures were positive for Pseudomonas aeruginosa in three cases and all three of these suffered lasting visual impairment. We describe our findings and discuss possible risk factors.
authors.affiliation: Manchester Royal Eye Hospital, Oxford Road, Manchester, M13 9WH, UK.
authors.forename: M A N
authors.initials: MA
authors.lastname: Whiting
authors.forename: M K
authors.initials: MK
authors.lastname: Raynor
authors.forename: P B
authors.initials: PB
authors.lastname: Morgan
authors.forename: P
authors.initials: P
authors.lastname: Galloway
authors.forename: D M
authors.initials: DM
authors.lastname: Tole
authors.forename: A
authors.initials: A
authors.lastname: Tullo
mesh_terms: D000328:Adult; D003262:Contact Lenses, Extended-Wear / Q000009:adverse effects* / Q000382:microbiology; D003320:Corneal Ulcer / Q000209:etiology*; D015818:Eye Infections, Bacterial / Q000209:etiology*; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D008297:Male; D011552:Pseudomonas Infections / Q000209:etiology*; D012307:Risk Factors; D020034:Silicone Gels; D014786:Vision Disorders / Q000209:etiology
chemical_list: D020034:Silicone Gels; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate