Is 11beta-hydroxysteroid dehydrogenase type 1 a good therapeutic target for blockade of glucocorticoid actions?
Chrousos
George P
GP
National Institute of Child Health and Human Development, National Institutes of Health, Building 10, Room 9D42, Bethesda, MD 20892, USA. chrousog@mail.nih.gov
D043205:11-beta-Hydroxysteroid Dehydrogenase Type 1 / Q000378:metabolism*; D000224:Addison Disease / Q000503:physiopathology; D003480:Cushing Syndrome / Q000503:physiopathology; D005938:Glucocorticoids / Q000037:antagonists & inhibitors*; D006801:Humans
D005938:Glucocorticoids; D043205:11-beta-Hydroxysteroid Dehydrogenase Type 1