title: An overview of Ensembl.
abstract: Ensembl (http://www.ensembl.org/) is a bioinformatics project to organize biological information around the sequences of large genomes. It is a comprehensive source of stable automatic annotation of individual genomes, and of the synteny and orthology relationships between them. It is also a framework for integration of any biological data that can be mapped onto features derived from the genomic sequence. Ensembl is available as an interactive Web site, a set of flat files, and as a complete, portable open source software system for handling genomes. All data are provided without restriction, and code is freely available. Ensembl's aims are to continue to "widen" this biological integration to include other model organisms relevant to understanding human biology as they become available; to "deepen" this integration to provide an ever more seamless linkage between equivalent components in different species; and to provide further classification of functional elements in the genome that have been previously elusive.
authors.affiliation: EMBL European Bioinformatics Institute, The Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK. birney@ebi.ac.uk
authors.forename: Ewan
authors.initials: E
authors.lastname: Birney
authors.forename: T Daniel
authors.initials: TD
authors.lastname: Andrews
authors.forename: Paul
authors.initials: P
authors.lastname: Bevan
authors.forename: Mario
authors.initials: M
authors.lastname: Caccamo
authors.forename: Yuan
authors.initials: Y
authors.lastname: Chen
authors.forename: Laura
authors.initials: L
authors.lastname: Clarke
authors.forename: Guy
authors.initials: G
authors.lastname: Coates
authors.forename: James
authors.initials: J
authors.lastname: Cuff
authors.forename: Val
authors.initials: V
authors.lastname: Curwen
authors.forename: Tim
authors.initials: T
authors.lastname: Cutts
authors.forename: Thomas
authors.initials: T
authors.lastname: Down
authors.forename: Eduardo
authors.initials: E
authors.lastname: Eyras
authors.forename: Xose M
authors.initials: XM
authors.lastname: Fernandez-Suarez
authors.forename: Paul
authors.initials: P
authors.lastname: Gane
authors.forename: Brian
authors.initials: B
authors.lastname: Gibbins
authors.forename: James
authors.initials: J
authors.lastname: Gilbert
authors.forename: Martin
authors.initials: M
authors.lastname: Hammond
authors.forename: Hans-Rudolf
authors.initials: HR
authors.lastname: Hotz
authors.forename: Vivek
authors.initials: V
authors.lastname: Iyer
authors.forename: Kerstin
authors.initials: K
authors.lastname: Jekosch
authors.forename: Andreas
authors.initials: A
authors.lastname: Kahari
authors.forename: Arek
authors.initials: A
authors.lastname: Kasprzyk
authors.forename: Damian
authors.initials: D
authors.lastname: Keefe
authors.forename: Stephen
authors.initials: S
authors.lastname: Keenan
authors.forename: Heikki
authors.initials: H
authors.lastname: Lehvaslaiho
authors.forename: Graham
authors.initials: G
authors.lastname: McVicker
authors.forename: Craig
authors.initials: C
authors.lastname: Melsopp
authors.forename: Patrick
authors.initials: P
authors.lastname: Meidl
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Mongin
authors.forename: Roger
authors.initials: R
authors.lastname: Pettett
authors.forename: Simon
authors.initials: S
authors.lastname: Potter
authors.forename: Glenn
authors.initials: G
authors.lastname: Proctor
authors.forename: Mark
authors.initials: M
authors.lastname: Rae
authors.forename: Steve
authors.initials: S
authors.lastname: Searle
authors.forename: Guy
authors.initials: G
authors.lastname: Slater
authors.forename: Damian
authors.initials: D
authors.lastname: Smedley
authors.forename: James
authors.initials: J
authors.lastname: Smith
authors.forename: Will
authors.initials: W
authors.lastname: Spooner
authors.forename: Arne
authors.initials: A
authors.lastname: Stabenau
authors.forename: James
authors.initials: J
authors.lastname: Stalker
authors.forename: Roy
authors.initials: R
authors.lastname: Storey
authors.forename: Abel
authors.initials: A
authors.lastname: Ureta-Vidal
authors.forename: K Cara
authors.initials: KC
authors.lastname: Woodwark
authors.forename: Graham
authors.initials: G
authors.lastname: Cameron
authors.forename: Richard
authors.initials: R
authors.lastname: Durbin
authors.forename: Anthony
authors.initials: A
authors.lastname: Cox
authors.forename: Tim
authors.initials: T
authors.lastname: Hubbard
authors.forename: Michele
authors.initials: M
authors.lastname: Clamp
mesh_terms: D019295:Computational Biology / Q000639:trends*