title: Multi-layer plastic/glass microfluidic systems containing electrical and mechanical functionality.
abstract: This paper describes an approach for fabricating multi-layer microfluidic systems from a combination of glass and plastic materials. Methods and characterization results for the microfabrication technologies underlying the process flow are presented. The approach is used to fabricate and characterize multi-layer plastic/glass microfluidic systems containing electrical and mechanical functionality. Hot embossing, heat staking of plastics, injection molding, microstenciling of electrodes, and stereolithography were combined with conventional MEMS fabrication techniques to realize the multi-layer systems. The approach enabled the integration of multiple plastic/glass materials into a single monolithic system, provided a solution for the integration of electrical functionality throughout the system, provided a mechanism for the inclusion of microactuators such as micropumps/valves, and provided an interconnect technology for interfacing fluids and electrical components between the micro system and the macro world.
authors.affiliation: School of Electrical & Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30332-0250, USA. gt0478a@prism.gatech.edu
authors.forename: Arum
authors.initials: A
authors.lastname: Han
authors.forename: Olivia
authors.initials: O
authors.lastname: Wang
authors.forename: Mason
authors.initials: M
authors.lastname: Graff
authors.forename: Swomitra K
authors.initials: SK
authors.lastname: Mohanty
authors.forename: Thayne L
authors.initials: TL
authors.lastname: Edwards
authors.forename: Ki-Ho
authors.initials: KH
authors.lastname: Han
authors.forename: A
authors.initials: A
authors.lastname: Bruno Frazier
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D004553:Electric Conductivity; D004867:Equipment Design; D005898:Glass / Q000737:chemistry*; D008567:Membranes, Artificial; D008839:Microelectrodes; D044085:Microfluidics / Q000295:instrumentation*; D008855:Microscopy, Electron, Scanning; D010781:Photography / Q000379:methods; D010969:Plastics / Q000737:chemistry*; D011312:Pressure
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial; D010969:Plastics