Antimicrobial chlorinated bibenzyls from the liverwort Riccardia marginata.
Three new chlorinated bibenzyls 3, 4, and 5, have been isolated from the New Zealand liverwort Riccardia marginata. This is the first report of simple chlorinated bibenzyls from any natural source. Compounds 3-5 showed antimicrobial activity against Bacillus subtilis, Candida albicans, and Trichophyton mentagrophytes.
Baek
Seung-Hwa
SH
Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan 570-749, Korea.
Phipps
Richard K
RK
Perry
Nigel B
NB
D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D001632:Bibenzyls / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects; D006843:Hydrocarbons, Chlorinated / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009520:New Zealand; D014249:Trichophyton / Q000187:drug effects
C486269:2,4,6-trichloro-3-hydroxybibenzyl; C486271:2,4-dichloro-3-hydroxybibenzyl; C486272:2-chloro-3-hydroxybibenzyl; D000935:Antifungal Agents; D001632:Bibenzyls; D006843:Hydrocarbons, Chlorinated