Rhinoscleroma in three siblings.
Rhinoscleroma is a chronic, granulomatous infectious disease that responds poorly to treatment. In recent years an increasing number of cases have been reported in nonendemic areas, explained largely by major migratory movements. We describe rhinoscleroma in three siblings. They had ulcerated but painless lesions, which bled spontaneously, and hemorrhagic scabs or crusts in their noses. In one child, the lesions had destroyed the entire left nasal ala and alar cartilage and most of the right. Dermatopathologic study identified the Mikulicz macrophages that contained organisms. It is possible that disposing factors could have been the neutropenia common to the three children and their poor living conditions. They were treated with a combination of trimethoprim-sulfamethoxazole and cefalexin, for a period of 3 months. We present this unusual case history of three siblings affected by a process that is relatively infrequent in our area of practice and is not considered very contagious. It is important to recognize the clinical signs characteristic of this disease, the diagnosis of which is not easy. Improvements in living conditions, hygiene, and health standards are essential prerequisites for its control and prevention.
Fernández-Vozmediano
J M
JM
Dermatology Service, University Hospital of Puerto Real, University of Cadiz, Cadiz, Spain. fdezvozmediano@wanadoo.es
Armario Hita
J C
JC
González Cabrerizo
A
A
D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D012226:Rhinoscleroma / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D035781:Siblings; D013211:Staphylococcus aureus / Q000302:isolation & purification; D013296:Streptococcus pneumoniae / Q000302:isolation & purification