title: Ulcerative colitis followed by the development of Behçet's disease.
abstract: A 34-year-old man who had a history of ulcerative colitis (UC) was admitted to our hospital with complaints of arthralgia, erythema nodosum, recurrent oral aphthous ulcers and bloody stools. A colonoscopy revealed multiple aphthous ulcers on his cecum and colon and also revealed a transmural ulcer on his rectum consistent with a diagnosis of UC. The patient was HLA-B51 positive. Based on clinical evidence [recurrent oral ulcers, skin lesions (erythema nodosum), positivity for pathergy test] this patient was diagnosed as having Behçet's disease with gastrointestinal involvement. We describe this rare case of Behçet's disease with colitis and discuss the difficulties in making a differential diagnosis between Behçet's disease and the inflammatory bowel diseases.
authors.affiliation: Institute of Rheumatology, Tokyo Women's Medical University, Tokyo.
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Kobashigawa
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Okamoto
authors.forename: Junko
authors.initials: J
authors.lastname: Kato
authors.forename: Hironari
authors.initials: H
authors.lastname: Shindo
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Imamura
authors.forename: Bun-ei
authors.initials: BE
authors.lastname: Iizuka
authors.forename: Masanori
authors.initials: M
authors.lastname: Tanaka
authors.forename: Masashi
authors.initials: M
authors.lastname: Uesato
authors.forename: Shu-ji
authors.initials: SJ
authors.lastname: Ohta
authors.forename: Chihiro
authors.initials: C
authors.lastname: Terai
authors.forename: Masako
authors.initials: M
authors.lastname: Hara
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Kamatani
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis; D003093:Colitis, Ulcerative / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D012809:Colon, Sigmoid / Q000473:pathology; D003113:Colonoscopy; D006801:Humans; D008297:Male; D012007:Rectum / Q000473:pathology; D013281:Stomatitis, Aphthous / Q000150:complications