title: CD4+ and CD8+ T-lymphocyte subsets in Zambian children.
abstract: Age-related changes in lymphocyte subsets in HIV-uninfected Zambian children are described. The total lymphocyte count and numbers of CD4+ and CD8+ T-lymphocytes declined with increasing age, while the percentage of CD4+ and CD8+ T-lymphocytes changed little during childhood. Girls between the ages of 12 and 71 months had a higher percentage of CD4+ T-lymphocytes and a higher CD4:CD8 ratio than did boys of a similar age.
authors.affiliation: Virology Laboratory, University Teaching Hospital, Lusaka, Zambia.
authors.forename: Zaza
authors.initials: Z
authors.lastname: Ndhlovu
authors.forename: Judith J
authors.initials: JJ
authors.lastname: Ryon
authors.forename: Diane E
authors.initials: DE
authors.lastname: Griffin
authors.forename: Mwaka
authors.initials: M
authors.lastname: Monze
authors.forename: Francis
authors.initials: F
authors.lastname: Kasolo
authors.forename: William J
authors.initials: WJ
authors.lastname: Moss
mesh_terms: D017677:Age Distribution; D018791:CD4 Lymphocyte Count; D018414:CD8-Positive T-Lymphocytes; D002648:Child; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000276:immunology*; D006801:Humans; D007223:Infant; D008297:Male; D017678:Sex Distribution; D015024:Zambia