title: Focal liver lesions in the cirrhotic patient: multislice spiral CT evaluation.
abstract: Imaging of the cirrhotic patient is a very difficult task due to the several morphologic and structural alterations that occur in the hepatic parenchyma. The presence of areas of fibrosis and regenerative nodules, often associated with haemodynamic alterations due to the portal hypertension, can make the identification of hepatocellular carcinoma very difficult or, in many cases, simulate the presence of tumour. Despite the use of state-of-the-art equipment and optimised study protocols, computed tomography (CT) has poor sensitivity for the detection of hepatocellular carcinoma. The present article illustrates the spiral CT findings that most often can be found in the evaluation of cirrhotic patients. In particular, the authors illustrate the CT patterns of regenerative nodules, dysplastic nodules, hepatocellular carcinomas and of all lesions that may mimic hepatocellular carcinoma.
authors.affiliation: Dipartimento di Scienze Radiologiche, Università degli Studi di Roma La Sapienza, Policlinico Umberto I, Rome. riannaccone@tiscali.it
authors.forename: Riccardo
authors.initials: R
authors.lastname: Iannaccone
authors.forename: Andrea
authors.initials: A
authors.lastname: Laghi
authors.forename: Carlo
authors.initials: C
authors.lastname: Catalano
authors.forename: Plinio
authors.initials: P
authors.lastname: Rossi
authors.forename: Roberto
authors.initials: R
authors.lastname: Passariello
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging; D006801:Humans; D008103:Liver Cirrhosis / Q000000981:diagnostic imaging*; D008113:Liver Neoplasms / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed