title: Relation between axial length of the eye and hypotensive effect of latanoprost in primary open angle glaucoma.
abstract: OBJECTIVE
  To study the effect of axial length on the hypotensive effect of latanoprost in primary open angle glaucoma (POAG) in a prospective, observational study.
  
  
  METHODS
  The authors measured axial length and baseline intraocular pressure (IOP) of 109 eyes with POAG, and then repeated the IOP measurements at 1, 3, and 6 months after starting treatment with latanoprost.
  
  
  RESULTS
  The mean IOP level was significantly lower in eyes with a shorter axial length compared with the eyes with a longer axial length both at 3 and 6 months of treatment (p = 0.03 and p = 0.04, respectively, ANOVA).
  
  
  CONCLUSIONS
  The hypotensive effect resulting from treatment with latanoprost could be related to ocular axial length.
authors.affiliation: University of Alcalá, Hospital Oftalmológico Internacional de Madrid. esther-arranz@ole.com
authors.forename: E
authors.initials: E
authors.lastname: Arranz-Marquez
authors.forename: M A
authors.initials: MA
authors.lastname: Teus
mesh_terms: D000704:Analysis of Variance; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001699:Biometry; D005123:Eye / Q000473:pathology*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D000077338:Latanoprost; D008297:Male; D011379:Prognosis; D011446:Prospective Studies; D011461:Prostaglandins F, Synthetic / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents; D011461:Prostaglandins F, Synthetic; D000077338:Latanoprost