title: TBAF-catalyzed synthesis of 5-substituted 1H-tetrazoles under solventless conditions.
abstract: Tetrabutylammonium fluoride (TBAF) is an efficient catalyst in the [3 + 2] cycloaddition reaction of organic nitriles 1 with trimethylsilyl azide (TMSN(3)) in solventless conditions. The corresponding 5-substituted 1H-tetrazoles 2 were obtained under mild conditions and in 80-97% yields.
authors.affiliation: Dipartimento di Chimica, Laboratorio di Chimica Organica, Università di Perugia, CEMIN (Centro di Eccellenza Materiali Innovativi per applicazioni chimiche, fisiche e biomediche), via Elce di Sotto 8, I-06123 Perugia, Italy.
authors.forename: David
authors.initials: D
authors.lastname: Amantini
authors.forename: Romina
authors.initials: R
authors.lastname: Beleggia
authors.forename: Francesco
authors.initials: F
authors.lastname: Fringuelli
authors.forename: Ferdinando
authors.initials: F
authors.lastname: Pizzo
authors.forename: Luigi
authors.initials: L
authors.lastname: Vaccaro