The effect of passive smoking on asthma symptoms,atopy,and airway hyperresponsiveness in schoolchildren.
Passive smoking is a major cause of respiratory morbidity, and is associated with increased bronchial responsiveness in children. To evaluate the effect of smoking by a parent on asthma symptoms, atopy, and airway hyperresponsiveness (AHR), we conducted a cross-sectional survey of 503 schoolchildren that involved questionnaires, spirometry, allergy testing, and a bronchial challenge test. If the PC20 methacholine was less than 16 mg/mL, the subject was considered to have AHR. The prevalence of a parent who smoked was 68.7%. The prevalence of AHR was 45.0%. The sensitization rate to common inhalant allergens was 32.6%. Nasal symptoms such as rhinorrhea, sneezing, nasal itching, and nasal obstruction were present in 42.7%. Asthma symptoms such as cough and wheezing were present in 55.4%. The asthma symptoms were significantly more prevalent in children who had a parent who smoked than in those whose parents did not. The nasal symptoms, atopy, and AHR did not differ according to whether a parent smoked. In a multiple logistic regression model, the asthma symptoms and atopy were independently associated with AHR, when adjusted for confounding variables. Passive smoking contributed to asthma symptoms in schoolchildren and was not an independent risk factor of airway hyperresponsiveness in an epidemiological survey.
Jang
An-Soo
AS
Department of Internal Medicine, Soonchunhyang University Hospital, Bucheon, Korea.
Choi
In-Seon
IS
Lee
Soong
S
Nam
Hae-Sung
HS
Kweon
Sun-Seok
SS
Son
Myung-Ho
MH
Lee
June-Hyuk
JH
Park
Sung Woo
SW
Kim
Do-Jin
DJ
Uh
Soo Taek
ST
Kim
Yong-Hoon
YH
Park
Choon-Sik
CS
D000328:Adult; D001249:Asthma / Q000453:epidemiology* / Q000503:physiopathology; D016535:Bronchial Hyperreactivity / Q000453:epidemiology* / Q000503:physiopathology; D002648:Child; D003625:Data Collection; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology* / Q000503:physiopathology; D008297:Male; D010290:Parents; D015995:Prevalence; D012307:Risk Factors; D014028:Tobacco Smoke Pollution / Q000009:adverse effects* / Q000706:statistics & numerical data*
D014028:Tobacco Smoke Pollution