title: [Reconstruction of descending aorta with adhesive pericardium patch: the experimental study].
abstract: OBJECTIVE
  Tissue adhesive is one of the recognized methods to stop bleeding from aorta. The aim of this experimental work was to use pericardium patch and long chain n-butil-2-cyanoacrilic tissue adhesive for the strengthening of descending aorta wall.
  
  
  METHODS
  Seven mongrel dogs were operated under general anesthesia and artificial ventilation support. Left side thoracotomy was done and descending aorta reached. The aorta was clamped from both side and opened by longitudinal incision. Pericardium patch, coated with cyanoacrilic adhesive (Hystacryl), was glued to aorta intimate layer. The aorta was sutured and normal blood flow restored. Morphological investigation was performed after 2, 4, and 24 hours and after 1 week.
  
  
  RESULTS
  In all cases interior of aorta looked normal; there were no evidence of tissue color changes, thrombosis or inflammation. Pericardial patch was tightly fixed to the aortic wall. Histological examination showed normal aorta wall and pericardium structure with glue layer between of them. There were no evidence of tissue cells necrosis, interstitial oedema or leukocytes penetration on examinated samples.
  
  
  CONCLUSIONS
  Long chain n-butyl-2-cyanoacrilic glue has inert properties on the aortic wall tissue. Pericardium patch, fixed with cyanoacrilic glue in aortis lumen, has no significant influence on the blood flow.
authors.affiliation: Heart Surgery Centre, Vilniaus University, Santariskiu 2, 2021 Vilnius, Lithuania.
authors.forename: Gintaras
authors.initials: G
authors.lastname: Turkevicius
authors.forename: Edvardas
authors.initials: E
authors.lastname: Zurauskas
authors.forename: Kestutis
authors.initials: K
authors.lastname: Zemaitis
mesh_terms: D000768:Anesthesia, General; D000818:Animals; D001013:Aorta, Thoracic / Q000601:surgery*; D001775:Blood Circulation; D004285:Dogs; D004659:Enbucrilate / Q000008:administration & dosage / Q000627:therapeutic use*; D005500:Follow-Up Studies; D010496:Pericardium / Q000637:transplantation*; D012121:Respiration, Artificial; D013908:Thoracotomy; D013997:Time Factors
chemical_list: D004659:Enbucrilate