title: Detection of serum Chlamydia pneumoniae (Cpn) immune complex and Cpn antibody in patients with coronary heart disease.
abstract: OBJECTIVE
  To understand the state of Chlamydia pneumoniae (Cpn) infection in patients with coronary heart disease (CHD), and explore the relationship between Cpn infection and the gonesis and progressin of CHD.
  
  
  METHODS
  By adopting sandwich method with double antibodies and indirect ELISA method, we detected serum Cpn immune complex and IgG antibody in 160 CHD patients (confirmed by coronary artery angiography) and 40 subjects without CHD.
  
  
  RESULTS
  The positivity rate of Cpn IgG type immune complex in the CHD group (63.8%) was significantly higher than that in the control group (40.0%, P<0.05), similar to the results of Cpn IgG antibody detection (65.0% vs 32.5%, P<0.05).
  
  
  CONCLUSIONS
  Cpn infection is closely connected with the CHD, but their exact relationship needs further exploration and study.
authors.affiliation: Institute of Cardiovascular Disease of Guangdong Province, Guangzhou 510100, China. sunyunyun54321@sina.com
authors.forename: Yun-yun
authors.initials: YY
authors.lastname: Sun
authors.forename: Wen-ling
authors.initials: WL
authors.lastname: Jiang
authors.forename: Xian-ling
authors.initials: XL
authors.lastname: Luo
authors.forename: Ji-yan
authors.initials: JY
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000097:blood*; D000936:Antigen-Antibody Complex / Q000097:blood*; D000942:Antigens, Bacterial / Q000097:blood*; D016993:Chlamydophila pneumoniae / Q000276:immunology*; D003327:Coronary Disease / Q000382:microbiology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged
chemical_list: D000907:Antibodies, Bacterial; D000936:Antigen-Antibody Complex; D000942:Antigens, Bacterial; D007074:Immunoglobulin G