title: Botulinum toxin in a case of hemimasticatory spasm with severe worsening during pregnancy.
abstract: Hemimasticatory spasm (HMS) is a rather uncommon movement disorder with a pathophysiology that is still unclear, although temporomasseter entrapment at the temporal fossa has been advanced. The authors present a case of HMS in a woman who experienced marked worsening in episode frequency and severity during pregnancy. Treatment with botulinum toxin led to marked improvement.
authors.affiliation: Movement Disorders and Parkinson's Disease Program, Institute of Applied Neurosciences, Hospital de Clínicas José de San Martín, Buenos Aires, Argentina.
authors.forename: María Graciela
authors.initials: MG
authors.lastname: Cersósimo
authors.forename: Alicia
authors.initials: A
authors.lastname: Bertoti
authors.forename: Claudia Uribe
authors.initials: CU
authors.lastname: Roca
authors.forename: Federico
authors.initials: F
authors.lastname: Micheli
mesh_terms: D000328:Adult; D018726:Anti-Dyskinesia Agents / Q000627:therapeutic use*; D001905:Botulinum Toxins / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004576:Electromyography / Q000379:methods; D005260:Female; D019569:Hemifacial Spasm / Q000188:drug therapy*; D006801:Humans; D008410:Masticatory Muscles / Q000187:drug effects / Q000503:physiopathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*
chemical_list: D018726:Anti-Dyskinesia Agents; D001905:Botulinum Toxins