[Assay of thyrocalcitonin in cervical lymph node using fine-needle washings for the diagnosis of disseminated medullary thyroid carcinoma].
Fine-needle aspiration biopsy of cervical lymph nodes was carried out in 22 patients with suspected metastatic involvement with medullary thyroid carcinoma (MTS). It was followed by cytopathological examination of aspirates and assay of of thyrocalcitonin (TCT) in fine-needle washings. TCT determinations proved highly informative as well as significantly high in all seven cases of MTS involvement (26-8,484.87 pg/ml, mean 2,208 +/- 1,722 pg/ml).
Isaev
P A
PA
Center for Medical Radiology Research, Russian Academy of Medical Sciences, Obninsk.
Medvedev
V S
VS
Il'in
A A
AA
Rumiantsev
P O
PO
Chebotareva
I V
IV
Terent'ev
P O
PO
Abrosimov
A Iu
AIu
Vtiurin
B M
BM
Parshkov
E M
EM
Severskaia
N V
NV
Marchenko
E V
EV
D000293:Adolescent; D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis*; D044963:Biopsy, Fine-Needle; D002116:Calcitonin / Q000032:analysis*; D018276:Carcinoma, Medullary / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000737:chemistry*; D008207:Lymphatic Metastasis / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009333:Neck; D013964:Thyroid Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology
D014408:Biomarkers, Tumor; D002116:Calcitonin