title: Interactions between copper and cadmium modify metal organ distribution in mature tilapia, Oreochromis mossambicus.
abstract: Sexually mature female tilapia were exposed to sublethal concentrations of waterborne Cu and/or Cd over 6 days, and subsequent body concentrations of these metals were determined in several organs. The results show that the distribution of Cu and Cd was metal and organ specific. This is demonstrated, for example, by the observation that in tilapia, Cu exposure did not result in Cu accumulation in the liver, whereas in the intestinal wall, notably high concentrations of Cu and Cd were measured in metal exposed fish. In addition to single metal exposed fish, we also determined Cu and Cd body distribution in Cu?Cd co-exposed fish. The observed interactions in metal accumulation were most pronounced in the organs of fish exposed to low, environmentally realistic, metal concentrations.
authors.affiliation: Department of Animal Physiology, Faculty of Science, University of Nijmegen, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands.
authors.forename: S M
authors.initials: SM
authors.lastname: Pelgrom
authors.forename: L P
authors.initials: LP
authors.lastname: Lamers
authors.forename: R A
authors.initials: RA
authors.lastname: Lock
authors.forename: P H
authors.initials: PH
authors.lastname: Balm
authors.forename: S E
authors.initials: SE
authors.lastname: Bonga