title: [Study of injury model in human umbilical vein endothelial cells].
abstract: OBJECTIVE
  To establishment the injury by oxidized low density lipoprotein in human umbilical vein endothelial cells.
  
  
  METHODS
  Huvecs were exposed to OX-LDL in vitro, then MTT and MDA of Huvecs were measured.
  
  
  RESULTS
  After endothelium cells were exposed to different dose of OX-LDL 24 hours, MTT was decreased significantly, especially in the high dose OX-LDL group.
  
  
  CONCLUSIONS
  OX-LDL could lead injury to Huvecs and might be related to atherosclerosis.
authors.affiliation: Institute of Health and Enviornment Medicine, Academy of Military Medical Sciences, Tianjin 300050, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Liu
authors.forename: Hong
authors.initials: H
authors.lastname: Chang
authors.forename: Zhenyuan
authors.initials: Z
authors.lastname: Xie
mesh_terms: D001161:Arteriosclerosis / Q000209:etiology; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D004730:Endothelium, Vascular / Q000473:pathology*; D006801:Humans; D008077:Lipoproteins, LDL / Q000494:pharmacology*; D008315:Malondialdehyde / Q000032:analysis; D014471:Umbilical Veins / Q000473:pathology
chemical_list: D008077:Lipoproteins, LDL; C099252:oxidized low density lipoprotein; D008315:Malondialdehyde