Mild cleavage of aryl mesylates: methanesulfonate as potent protecting group for phenols.
[reaction: see text] A mild protocol for the chemoselective deprotection of aryl methanesulfonates is described. The transformation can be conducted on highly functionalized substrates and renders the methanesulfonate a useful, previously underutilized protecting group for phenols.
Ritter
Tobias
T
Laboratorium für Organische Chemie, ETH Hönggerberg, CH-8093 Zürich, Switzerland.
Stanek
Kyrill
K
Larrosa
Igor
I
Carreira
Erick M
EM
D008698:Mesylates / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D010636:Phenols / Q000138:chemical synthesis* / Q000737:chemistry*
D008698:Mesylates; D010636:Phenols