title: An iterative approach to novel polyamines via nucleophilic ring-opening of aziridinium ions with beta-amino alcohols.
abstract: An iterative procedure for the synthesis of a novel class of synthetic polyamines has been developed, utilising the regioselective ring-opening of aziridinium ion intermediates; facile N-allyl deprotection of intermediate polyamines allows the rapid construction of high molecular weight, stereochemically defined compounds in a convergent manner.
authors.affiliation: Department of Chemistry, University of Leeds, Leeds, UK LS2 9JT.
authors.forename: Christopher
authors.initials: C
authors.lastname: McKay
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Wilson
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Rayner
mesh_terms: D000605:Amino Alcohols / Q000737:chemistry*; D001388:Aziridines / Q000737:chemistry*; D007477:Ions / Q000737:chemistry; D015394:Molecular Structure; D008970:Molecular Weight; D011073:Polyamines / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000605:Amino Alcohols; D001388:Aziridines; D007477:Ions; D011073:Polyamines