title: -1 frameshifting at a CGA AAG hexanucleotide site is required for transposition of insertion sequence IS1222.
abstract: The discovery of programmed -1 frameshifting at the hexanucleotide shift site CGA_AAG, in addition to the classical X_XXY_YYZ heptanucleotide shift sequences, prompted a search for instances among eubacterial insertion sequence elements. IS1222 has a CGA_AAG shift site. A genetic analysis revealed that frameshifting at this site is required for transposition.
authors.affiliation: Laboratoire de Microbiologie et Génétique Moléculaire, UMR5100 Centre National de la Recherche Scientifique et Université Paul Sabatier, Toulouse 31062, France.
authors.forename: Nina
authors.initials: N
authors.lastname: Mejlhede
authors.forename: Patricia
authors.initials: P
authors.lastname: Licznar
authors.forename: Marie-Françoise
authors.initials: MF
authors.lastname: Prère
authors.forename: Norma M
authors.initials: NM
authors.lastname: Wills
authors.forename: Raymond F
authors.initials: RF
authors.lastname: Gesteland
authors.forename: John F
authors.initials: JF
authors.lastname: Atkins
authors.forename: Olivier
authors.initials: O
authors.lastname: Fayet
mesh_terms: D001483:Base Sequence; D004251:DNA Transposable Elements; D018965:Frameshifting, Ribosomal; D008969:Molecular Sequence Data; D020638:Rahnella / Q000235:genetics*
chemical_list: D004251:DNA Transposable Elements