Development of an indole safety-catch linker using analytical constructs.
The development, evaluation, and application of a novel safety-catch linker for solid-phase synthesis based on an N-tosylindole is reported. The development of this linker using analytical constructs to aid analysis is discussed.
Scicinski
Jan J
JJ
GlaxoSmithKline Cambridge Chemistry Laboratory and Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. jscicins@alzus.jnj.com
Congreve
Miles S
MS
Ley
Steven V
SV