Serotonin-3 receptors in the actions of alcohol, alcohol reinforcement, and alcoholism.
This article represents the proceedings of a symposium at the 2003 annual meeting of the Research Society on Alcoholism in Fort Lauderdale, FL. The organizers and chairs were William J. McBride and David M. Lovinger. The presentations were (1) Mechanisms of alcohol potentiation of 5-HT3 receptor function, by David M. Lovinger and Tina Machu; (2) Chronic alcohol drinking alters 5-HT3 receptors regulating the mesolimbic dopamine system, by Richard J. Thielen; (3) 5-HT3 receptors in the VTA regulate alcohol drinking and the reinforcing effects of alcohol, by Zachary A. Rodd and James M. Murphy; and (4) Ondansetron as a treatment for "biological" alcoholism, by John D. Roache and Bankole A. Johnson.
McBride
William J
WJ
Indiana University School of Medicine, Indianapolis, Indiana, USA. wmcbride@iupui.edu
Lovinger
David M
DM
Machu
Tina
T
Thielen
Richard J
RJ
Rodd
Zachary A
ZA
Murphy
James M
JM
Roache
John D
JD
Johnson
Bankole A
BA
D000428:Alcohol Drinking / Q000188:drug therapy / Q000378:metabolism; D000437:Alcoholism / Q000188:drug therapy / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D017294:Ondansetron / Q000494:pharmacology / Q000627:therapeutic use; D044406:Receptors, Serotonin, 5-HT3 / Q000378:metabolism*; D012054:Reinforcement, Psychology; D058831:Serotonin 5-HT3 Receptor Antagonists; D012955:Societies, Medical; D014481:United States
D044406:Receptors, Serotonin, 5-HT3; D058831:Serotonin 5-HT3 Receptor Antagonists; D000431:Ethanol; D017294:Ondansetron