title: The overlap of inflammatory bowel disease and diverticular disease.
abstract: An overlap of inflammatory bowel disease and diverticular disease has long been recognized. Crohn's disease and diverticulitis share clinical and radiologic features but usually differ in histopathologic findings. There is a suggestion, however, that even the characteristic pathology of Crohn's disease can be a secondary reaction to diverticulitis. It is possible, moreover, that the presence of Crohn's disease in association with diverticulosis predisposes to the development of diverticulitis. Finally, an apparently distinct form of segmental colitis associated with sigmoid diverticula has been described further contributing to the overlap of inflammatory bowel disease and diverticular disease.
authors.affiliation: Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Rabb 420, Boston, MA 02215, USA. mpepperc@bidmc.harvard.edu
authors.forename: Mark A
authors.initials: MA
authors.lastname: Peppercorn
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003092:Colitis / Q000150:complications / Q000628:therapy; D012809:Colon, Sigmoid / Q000473:pathology; D003424:Crohn Disease / Q000150:complications* / Q000628:therapy; D004239:Diverticulitis, Colonic / Q000150:complications / Q000628:therapy; D004240:Diverticulum / Q000150:complications* / Q000628:therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D015212:Inflammatory Bowel Diseases / Q000150:complications* / Q000628:therapy; D012810:Sigmoid Diseases / Q000150:complications / Q000628:therapy
chemical_list: D000900:Anti-Bacterial Agents; D007166:Immunosuppressive Agents