title: Capillary microextraction on sol-gel dendrimer coatings.
abstract: Sol-gel capillary microextraction (CME) is a new direction in the solventless sample preparation for the preconcentration of trace analytes, and presents significant interest in environmental, pharmaceutical, petrochemical, biomedical, agricultural, food, flavor, and a host of other important areas. It utilizes advanced material properties of organic-inorganic hybrid sol-gel polymers to perform efficient extraction and preconcentration of target compounds from a wide variety of matrices. In the present work, a novel benzyl-terminated dendron-based sol-gel coating was developed for CME. A detailed investigation was conducted to evaluate the performance of the newly developed sol-gel dendrimer coatings to perform solventless extraction of a wide range of polar and nonpolar analytes. The characteristic branched architecture of dendrons makes them structurally superior extraction media compared with their traditional linear polymeric counterparts. Sol-gel chemistry was used to chemically immobilize dendritic macromolecules on fused silica capillary inner surface. Due to the strong chemical bonding with the capillary inner walls, sol-gel dendron coatings showed excellent thermal and solvent stability in capillary microextraction in hyphenation with chromatographic analysis. Efficient extraction of a wide range of analytes from their aqueous solutions was accomplished using sol-gel dendron coated fused silica capillaries. Low parts per trillion level detection limits were achieved in CME-GC for both polar and nonpolar analytes including polyaromatic hydrocarbons (PAHs), aldehydes, ketones, phenols, and alcohols.
authors.affiliation: Department of Chemistry, University of South Florida, 4202 E. Fowler Avenue, Tampa, FL 33620-5250, USA.
authors.forename: Abuzar
authors.initials: A
authors.lastname: Kabir
authors.forename: Christina
authors.initials: C
authors.lastname: Hamlet
authors.forename: Kyung Soo
authors.initials: KS
authors.lastname: Yoo
authors.forename: George R
authors.initials: GR
authors.lastname: Newkome
authors.forename: Abdul
authors.initials: A
authors.lastname: Malik
mesh_terms: D002850:Chromatography, Gel / Q000379:methods*; D005782:Gels; D008855:Microscopy, Electron, Scanning; D012680:Sensitivity and Specificity
chemical_list: D005782:Gels