title: ICM0301s, new angiogenesis inhibitors from Aspergillus sp. F-1491. II. Physico-chemical properties and structure elucidation.
abstract: ICM0301A (1), B (2) and their congeners (3 approximately 8) were isolated from a culture broth of Aspergillus sp. F-1491 as new angiogenesis inhibitors. Their structures were elucidated by spectroscopic analyses. ICM0301A and B have a substituted decalin skeleton containing two oxirane rings.
authors.affiliation: Microbial Chemistry Research Center, Numazu Bio-Medical Research Institute, 18-24 Miyamoto, Numazu-shi, Shizuoka 410-0301, Japan. numazu@bikaken.or.jp
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Someno
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kumagai
authors.forename: Shun-ichi
authors.initials: S
authors.lastname: Ohba
authors.forename: Masahide
authors.initials: M
authors.lastname: Amemiya
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Naganawa
authors.forename: Masaaki
authors.initials: M
authors.lastname: Ishizuka
authors.forename: Daishiro
authors.initials: D
authors.lastname: Ikeda
mesh_terms: D020533:Angiogenesis Inhibitors / Q000737:chemistry*; D001230:Aspergillus / Q000737:chemistry*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004852:Epoxy Compounds / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D009281:Naphthalenes / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D020533:Angiogenesis Inhibitors; D004852:Epoxy Compounds; D009281:Naphthalenes