title: "Primary" aggressive chondroblastoma of the humerus: a case report.
abstract: BACKGROUND
  Chondroblastomas are rare epiphyseal bone tumors. Very few cases with extra-cortical aggressive soft tissue invasion or metastasis are reported.
  
  
  METHODS
  We report a 28 year-old adult male who presented with a large swelling over the left shoulder region. Pre-operative imaging revealed a large tumor arising from upper end of humerus with extensive soft tissue involvement necessitating a fore-quarter amputation. Patient received adjuvant radiation.
  
  
  CONCLUSIONS
  This patient is one of the largest chondroblastomas to be reported. Although chondroblastomas are typically benign, rarely they can be locally aggressive or metastatic. Early diagnosis and institution of proper primary therapy would prevent mutilating surgeries and recurrences.
authors.affiliation: Department Of Surgical Oncology, M. S. Ramaiah Medical College & Hospital, Bangalore-560054, India. drkhari@yahoo.com
authors.forename: K
authors.initials: K
authors.lastname: Harish
authors.forename: M G
authors.initials: MG
authors.lastname: Janaki
authors.forename: N Kishore
authors.initials: NK
authors.lastname: Alva
mesh_terms: D000328:Adult; D000671:Amputation, Surgical; D001859:Bone Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D002804:Chondroblastoma / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D018450:Disease Progression; D006801:Humans; D006811:Humerus / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006945:Hyperhidrosis / Q000209:etiology; D008297:Male; D009361:Neoplasm Invasiveness; D011859:Radiography; D011867:Radioisotope Teletherapy; D018714:Radiotherapy, Adjuvant