title: Measuring the nonlinear elastic properties of tissue-like phantoms.
abstract: A direct mechanical system simultaneously measuring external force and deformation of samples over a wide dynamic range is used to obtain force-displacement curves of tissue-like phantoms under plain strain deformation. These measurements, covering a wide deformation range, then are used to characterize the nonlinear elastic properties of the phantom materials. The model assumes incompressible media, in which several strain energy potentials are considered. Finite-element analysis is used to evaluate the performance of this material characterization procedure. The procedures developed allow calibration of nonlinear elastic phantoms for elasticity imaging experiments and finite-element simulations.
authors.affiliation: Biomedical Engineering Department, University of Michigan, Ann Arbor, MI 48109-2125, USA. erkamp@eecs.umich.edu
authors.forename: Ramon Q
authors.initials: RQ
authors.lastname: Erkamp
authors.forename: Andrei R
authors.initials: AR
authors.lastname: Skovoroda
authors.forename: Stanislav Y
authors.initials: SY
authors.lastname: Emelianov
authors.forename: Matthew
authors.initials: M
authors.lastname: O'Donnell
mesh_terms: D000328:Adult; D000465:Algorithms; D003238:Connective Tissue / Q000000981:diagnostic imaging* / Q000502:physiology*; D004548:Elasticity; D005240:Feasibility Studies; D005260:Female; D020342:Finite Element Analysis; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008954:Models, Biological; D009038:Motion; D017711:Nonlinear Dynamics; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013314:Stress, Mechanical; D014463:Ultrasonography / Q000295:instrumentation* / Q000379:methods*; D014732:Vibration