Posttransplantation disseminated coccidioidomycosis acquired from donor lungs.
A North Carolinian developed fatal coccidioidomycosis immediately after bilateral lung transplantation. The donor had previously traveled to Mexico, and the recipient had no travel history to an area where Coccidioides immitis is endemic. Immunosuppressive therapy of the transplant recipient likely reactivated latent Coccidioides infection in the donor lungs, leading to posttransplant coccidioidomycosis.
Miller
Melissa B
MB
Clinical Microbiology-Immunology Laboratories, University of North Carolina Hospitals, Chapel Hill, North Carolina 27514, USA. mbmiller@unch.unc.edu
Hendren
Ryan
R
Gilligan
Peter H
PH
D002177:Candidiasis / Q000209:etiology; D003045:Coccidioides / Q000302:isolation & purification; D003047:Coccidioidomycosis / Q000473:pathology / Q000635:transmission*; D017809:Fatal Outcome; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008172:Lung Diseases, Fungal / Q000473:pathology / Q000635:transmission; D016040:Lung Transplantation / Q000009:adverse effects*; D008875:Middle Aged; D014019:Tissue Donors
D007166:Immunosuppressive Agents