Spatio-temporal brain activation profiles associated with line bisection judgments and double simultaneous visual stimulation.
We used magnetic source imaging (MSI) to investigate the spatio-temporal patterns of brain activity associated with line bisection judgments and double simultaneous visual stimulation in 14 healthy adults. Consistent with lesion and hemodynamic neuroimaging studies, we found the greatest number of activity sources in right inferior parietal cortex. These sources were most prominent, on average, between 200 and 300 ms after the onset of single (left, right, or center) target stimuli. A greater number of significant activity sources were found in right inferior parietal, occipital, and prefrontal cortices during bilateral compared with unilateral stimulus presentation. Based on these observations, we suggest that a more parsimonious physiological explanation of visual extinction than the hemispheric rivalry account may be the additional neuronal excitation required in right occipital and parietal cortices for accurate bilateral visual perception.
Billingsley
R L
RL
Division of Clinical Neurosciences, Department of Neurosurgery, Vivian L. Smith Center for Neurologic Research, University of Texas-Houston Medical School, 1333 Moursund Street, Suite H114, Houston, TX 77030, USA. rebecca.i.billingsley@uth.tmc.edu
Simos
P G
PG
Sarkari
S
S
Fletcher
J M
JM
Papanicolaou
A C
AC
D000328:Adult; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000033:anatomy & histology / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007600:Judgment / Q000502:physiology*; D015225:Magnetoencephalography / Q000379:methods; D008297:Male; D010775:Photic Stimulation; D011597:Psychomotor Performance / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D013028:Space Perception / Q000502:physiology*; D013997:Time Factors