A benzil and isoflavone derivatives from Derris scandens Benth.
A benzil derivative: scandione, 2',2"-dihydroxy-4'-methoxy-4",5"-methylenedioxybenzil and two isoflavones: scandenal, 3'-formyl-4',5-dihydroxy-2",2"-dimethylchromeno-[6,7:5",6"]isoflavone and scanderone, 4',5-dihydroxy-3'-prenyl-2",2"-dimethylchromeno-[7,8:6",5"]isoflavone together with fifteen known compounds were isolated from the stem of D. scandens. Their structures were determined by spectroscopic methods. Radical scavenging, antibacterial and hypertensive activities of some of the compounds were investigated.
Mahabusarakam
W
W
Department of Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla, 90112, Thailand. mwilawan@ratree.psu.ac.th
Deachathai
S
S
Phongpaichit
S
S
Jansakul
C
C
Taylor
W C
WC
D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000959:Antihypertensive Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001713:Biphenyl Compounds; D001794:Blood Pressure / Q000187:drug effects; D029866:Derris / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D007529:Isoflavones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008297:Male; D016106:Methicillin Resistance; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010658:Phenylglyoxal / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D010851:Picrates / Q000037:antagonists & inhibitors; D018547:Plant Stems / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D013211:Staphylococcus aureus / Q000187:drug effects / Q000235:genetics
D000900:Anti-Bacterial Agents; D000959:Antihypertensive Agents; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D007529:Isoflavones; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl; D010658:Phenylglyoxal; C006697:benzil