title: Antibody-catalyzed aminolysis of a chloropyrimidine derivative.
abstract: We have generated antibody FTB8E9 by immunization with the designed hapten to catalyze the aminolysis reaction of a chloropyrimidine derivative.
authors.affiliation: The Skaggs Institute for Chemical Biology and the Departments of Chemistry and Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA. ftanaka@scripps.edu
authors.forename: Fujie
authors.initials: F
authors.lastname: Tanaka
authors.forename: Fabiola
authors.initials: F
authors.lastname: Flores
authors.forename: Diane
authors.initials: D
authors.lastname: Kubitz
authors.forename: Richard A
authors.initials: RA
authors.lastname: Lerner
authors.forename: Carlos F
authors.initials: CF
authors.lastname: Barbas
mesh_terms: D000906:Antibodies / Q000737:chemistry / Q000378:metabolism*; D002384:Catalysis; D011743:Pyrimidines / Q000737:chemistry / Q000378:metabolism*
chemical_list: D000906:Antibodies; D011743:Pyrimidines