title: [Ulcerative colitis and Crohn's disease].
abstract: There is an enigma of inflammatory bowel diseases, despite significant advantages during last 10 years in medicamentous and surgical treatment. Ulcerative colitis and Crohns disease are chronic with remissions and recidives. Crohns disease involves any part of digestive tube. Histological changes in ulcerative colitis are: inflammation of mucosa and submucosal tissue, crypt abscesses and ulcerations, pseudopolpys, bowel shortening and toxic megacolon in severe inflammation. In Crohns disease, transmural inflammation, "jumping lesions", deeper ulcerations, coble-stone mucosa, progressive fibrosis, granuloma with gigantic epithelial cells.
  
  
  METHODS
  ulcerative colitis: mesalazine, rectal 5-ASA and hydrocortisone enemas, surgery. Crohns disease: mesalazine and prednisolone. For terminal ilcitis, corticosteroid budesonid could be applied. Severe symptomatic disease: hospitalization, parenteral nutrition, antibiotics, prednisone, surgery in partial bowel obstruction, fistulas, abscessus, perforation.
authors.affiliation: Gastroenteroloski odjel, Univerzitetsko-klinicki centar, Klinika za interne bolesti, Tuzla.
authors.forename: Nada
authors.initials: N
authors.lastname: Pavlović-Calić
mesh_terms: D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000628:therapy; D003424:Crohn Disease / Q000175:diagnosis / Q000628:therapy; D006801:Humans