title: Management of long-term catheter-related Brevibacterium bacteraemia.
abstract: Brevibacterium has been reported as a rare cause of implanted-device infection. In two cases of recurrent Brevibacterium casei bacteraemia associated with infection of surgically implanted intravascular devices, relapse occurred 2 and 5 months, respectively, after completion of therapy with vancomycin via the infected catheter. A second intravenous antibiotic therapy course by the antibiotic-lock technique led to bacteriological cure in one patient. Molecular typing results demonstrated that the recurrent bacteraemia was caused by the same strain. Implanted-device removal may be necessary, in addition to appropriate antibiotics, for successful management of such infections.
authors.affiliation: Department of Microbiology, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium.
authors.forename: I
authors.initials: I
authors.lastname: Beukinga
authors.forename: H
authors.initials: H
authors.lastname: Rodriguez-Villalobos
authors.forename: A
authors.initials: A
authors.lastname: Deplano
authors.forename: F
authors.initials: F
authors.lastname: Jacobs
authors.forename: M J
authors.initials: MJ
authors.lastname: Struelens
mesh_terms: D000193:Actinomycetales Infections / Q000188:drug therapy / Q000382:microbiology / Q000628:therapy*; D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology / Q000628:therapy*; D001951:Brevibacterium / Q000187:drug effects; D002408:Catheters, Indwelling / Q000382:microbiology*; D020878:Device Removal; D004866:Equipment Contamination; D005260:Female; D006801:Humans; D008297:Male; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin