Hysteroscopic metroplasty under laparoscopic guidance in infertile women with septate uteri: follow-up of reproductive outcome.
OBJECTIVE
To evaluate the effectiveness of hysteroscopic metroplasty under laparoscopic guidance in the treatment of infertile women with a diagnosis of septate uterus and the impact of this surgical procedure on reproductive outcome.


METHODS
From January 1996 to December 2000, 36 women referred to our endoscopy center underwent hysteroscopic metroplasty. Follow-up covered the incidence of pregnancy, term pregnancies and mode of delivery.


RESULTS
The mean age of the patients was 31.9 +/- 3.9 years (range, 23-39). One patient (3%) dropped out during follow-up. There were no intraoperative or postoperative complications. The mean interval from metroplasty to conception was 11.3 +/- 9.2 months (range, 2.0-35.5). Twenty of 35 (57%) women had a history of > or = 1 spontaneous abortions, and 18 of the 20 (90%) achieved pregnancy, with 15 of 18 (83%) term deliveries (10 vaginal deliveries and 5 cesarean sections). Fifteen of 35 patients (43%) were nulliparous, and 8 of 15 (53.3%) had term deliveries (1 cesarean section).


CONCLUSIONS
Hysteroscopic metroplasty under laparoscopic guidance is safe, allows spontaneous delivery and short-term pregnancy planning, is particularly successful in infertile women with a history of > or = 1 spontaneous abortions.
Litta
Pietro
P
Department of Gynecology and Obstetrics, University of Padua, Padua, Italy.
Pozzan
Chiara
C
Merlin
Federica
F
Sacco
Giuseppe
G
Saccardi
Carlo
C
Ambrosini
Guido
G
Capobianco
Giampiero
G
Dessole
Salvatore
S
D000328:Adult; D036861:Delivery, Obstetric; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015907:Hysteroscopy / Q000379:methods*; D007247:Infertility, Female / Q000209:etiology* / Q000601:surgery*; D010535:Laparoscopy / Q000379:methods*; D011247:Pregnancy; D011256:Pregnancy Outcome; D014599:Uterus / Q000002:abnormalities* / Q000601:surgery*