Multiple symmetric lipomatosis (Madelung's disease): report of two cases.
Multiple symmetric lipomatosis (Madelung's disease) is a rare disease characterized by non-encapsulated adipose deposits in the neck, the superior part of the trunk and, very rarely, in the limbs. It is common in middle-aged Caucasian Mediterranean males but very rare in Chinese people. We describe two cases of Madelung's disease: both patients presented complaining of a development of a painless neck mass that was increasing in size. Panendoscopy was normal. Both underwent incisional biopsies that revealed benign adipose tissue characterizing Madelung's disease. We discuss the clinical presentation, associated morbidity, and treatments for Madelung's disease.
Wu
Chung-Shin
CS
Department of Otolaryngology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Wang
Ling-Feng
LF
Tsai
Kun-Bow
KB
Tai
Chih-Feng
CF
Kuo
Wen-Rei
WR
D000328:Adult; D006801:Humans; D008069:Lipomatosis, Multiple Symmetrical / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged