title: Performance optimization of spectroscopic process analyzers.
abstract: To increase the power and the robustness of spectroscopic process analyzers, methods are needed that suppress the spectral variation that is not related to the property of interest in the process stream. An approach for the selection of a suitable method is presented. The approach uses the net analyte signal (NAS) to analyze the situation and to select methods to suppress the nonrelevant spectral variation. The empirically determined signal-to-noise of the NAS is used as a figure of merit. The advantages of the approach are (i). that the error of the reference method does not affect method selection and (ii). that only a few spectral measurements are needed. A diagnostic plot is proposed that guides the user in the evaluation of the particular suppression method. As an example, NIR spectroscopic monitoring of a mol-sieve separation process is used.
authors.affiliation: Process Analysis and Chemometrics, University of Amsterdam, Nieuwe Achtergracht 166, 1018 WV Amsterdam, The Netherlands.
authors.forename: Hans F M
authors.initials: HF
authors.lastname: Boelens
authors.forename: Wim Th
authors.initials: WT
authors.lastname: Kok
authors.forename: Onno E
authors.initials: OE
authors.lastname: De Noord
authors.forename: Age K
authors.initials: AK
authors.lastname: Smilde