title: Increased VLDL-TAG turnover during and after acute moderate-intensity exercise.
abstract: OBJECTIVE
  Breakdown rates of very low density lipoprotein triacylglycerols (VLDL-TAG) were quantified before (3 h), during (45 min), and after (3 h) moderate physical exercise at 40% VO2 max in young sedentary subjects (four male and four female, age 29.8 +/-1.6 yr, BMI 24.1 +/- 0.9 kg x m, VO2max 37.0 +/- 1.7 mL x kg x min), using boluses of H5-glycerol (100 mu mol x kg) and H2-palmitate (6.6 mu mol x kg). The catabolic rates of VLDL-TAG were calculated from the decay in the isotopic enrichment using a single-pool model. The results were compared with those obtained during 6 h of rest in five of the same volunteers.
  
  
  RESULTS
  VLDL-TAG concentration remained constant throughout the study with exercise (P = NS). The fractional catabolic rate was nearly doubled from rest to exercise (P < 0.05 vs rest) and increased to an even greater extent during the early phase of recovery (P < 0.001 vs rest). During the late recovery phase, the value returned to the preexercise value (P = NS vs rest). The values for the absolute catabolic rate (kabs) followed the same trend.
  
  
  CONCLUSIONS
  VLDL-TAG turnover was increased during exercise and during the early phase of recovery.
authors.affiliation: Protein and Energy Metabolism Research Unit, Human Nutrition Laboratory, Clermont Ferrand, France.
authors.forename: Béatrice
authors.initials: B
authors.lastname: Morio
authors.forename: Ulf
authors.initials: U
authors.lastname: Holmbäck
authors.forename: Dennis
authors.initials: D
authors.lastname: Gore
authors.forename: Robert R
authors.initials: RR
authors.lastname: Wolfe
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D016022:Case-Control Studies; D003903:Deuterium; D015444:Exercise / Q000502:physiology*; D005260:Female; D005990:Glycerol; D006801:Humans; D016014:Linear Models; D008079:Lipoproteins, VLDL / Q000097:blood*; D008297:Male; D010168:Palmitates; D012129:Respiratory Function Tests; D014280:Triglycerides / Q000097:blood*
chemical_list: D008079:Lipoproteins, VLDL; D010168:Palmitates; D014280:Triglycerides; C030106:very low density lipoprotein triglyceride; D003903:Deuterium; D005990:Glycerol