title: Transport of contrast agents in contrast-enhanced magnetic resonance angiography.
abstract: Contrast-enhanced magnetic resonance angiography (CEMRA) often appears to display vessels with good resolution, but it does not adequately visualize the throat of a tight stenosis. Image quality in CEMRA is also governed by the timing of contrast injection and data acquisition. We developed a numerical technique to predict the image appearance of a target vessel by taking into account the passage of contrast agent. Experiments were conducted on a phantom with both centric and linear ordering. An effort to prolong the duration in which the contrast passes by employing a double injection technique gives a wider window of opportunity to acquire quality images.
authors.affiliation: Department of Radiology, University of California at San Francisco, San Francisco, CA, USA. liang@radiology.ucsf.edu
authors.forename: Liang-Der
authors.initials: LD
authors.lastname: Jou
authors.forename: Joseph
authors.initials: J
authors.lastname: Rapp
authors.forename: D
authors.initials: D
authors.lastname: Saloner
mesh_terms: D001692:Biological Transport; D001783:Blood Flow Velocity / Q000187:drug effects; D017536:Carotid Artery, Common / Q000187:drug effects / Q000503:physiopathology; D016893:Carotid Stenosis / Q000175:diagnosis / Q000378:metabolism; D003287:Contrast Media / Q000008:administration & dosage / Q000493:pharmacokinetics*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007275:Injections, Intravenous; D018810:Magnetic Resonance Angiography / Q000379:methods; D019047:Phantoms, Imaging; D012680:Sensitivity and Specificity; D013997:Time Factors
chemical_list: D003287:Contrast Media