Microarray profiling of antiviral antibodies for the development of diagnostics, vaccines, and therapeutics.
Multiplex analysis of antiviral antibody (Ab) responses provides a potentially powerful strategy for viral diagnosis, prognostication, and development of vaccines and prophylactic Abs. In the coming years, advancements in proteomic technologies will provide even more robust methods to characterize antiviral Ab responses. Biomedical researchers will be faced with the exciting challenge of identifying antiviral Ab specificities that correlate with improved outcomes and efficacious interventions, and translating the findings into more effective diagnostics, prophylactics, and therapeutics.
Neuman de Vegvar
Henry E
HE
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.
Robinson
William H
WH
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D000956:Antigens, Viral / Q000276:immunology*; D018604:Epitope Mapping / Q000379:methods; D006678:HIV / Q000276:immunology; D006801:Humans; D040081:Protein Array Analysis / Q000379:methods*; D040901:Proteomics / Q000379:methods*; D015302:Simian Immunodeficiency Virus / Q000276:immunology; D014765:Viral Vaccines
D000914:Antibodies, Viral; D000956:Antigens, Viral; D014765:Viral Vaccines