Propionic acidemia and zinc deficiency presenting as necrolytic migratory erythema.
Necrolytic migratory erythema was first described in 1942 in a patient with pancreatic islet cell carcinoma. The disease can, however, have other etiologies including nutritional dermatoses. Here, we describe the clinicopathological picture of a 7-year-old female patient who presented with necrolytic migratory erythema which we believe is secondary to a rare combination of zinc deficiency and propionic acidemia.
Al-Rikabi
Ammar C
AC
Department of Pathology, Hamad General Hospital, Doha, Qatar. ammar_rikabi@hotmail.com
Al-Homsi
Hala I
HI
D000169:Acrodermatitis / Q000209:etiology* / Q000473:pathology; D001706:Biopsy; D002648:Child; D003937:Diagnosis, Differential; D004890:Erythema / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D009336:Necrosis; D011422:Propionates / Q000097:blood*; D012867:Skin / Q000473:pathology; D012875:Skin Diseases, Metabolic / Q000175:diagnosis* / Q000473:pathology; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis* / Q000473:pathology; D015032:Zinc / Q000172:deficiency*
D011422:Propionates; D015032:Zinc; C029658:propionic acid