title: Postoperative nausea and vomiting in the plastic surgery patient.
abstract: Despite great advances in modern medicine, postoperative nausea and vomiting (PONV) continue to be a significant problem without a definitive cure. This article describes a prospective study conducted with 143 plastic surgery patients at a single institution between 1998 and 2000 to identify preoperative risk factors for PONV that may be specific to plastic surgery patients. In addition, a prophylactic regimen was identified that demonstrated a decrease in the incidence of PONV from the published incidence of 22% to 3%. The regimen includes the use of multiple antiemetic agents including ondansetron (Zofran) promethazine (Phenergan), and metoclopramide (Reglan), with the addition of dexamethasone (Decadron) in selected cases
authors.affiliation: Houston, TX 77002, USA.
authors.forename: Robert Lee
authors.initials: RL
authors.lastname: Steely
authors.forename: Donald R
authors.initials: DR
authors.lastname: Collins
authors.forename: Benjamin E
authors.initials: BE
authors.lastname: Cohen
authors.forename: Kim
authors.initials: K
authors.lastname: Bass
mesh_terms: D000556:Ambulatory Surgical Procedures / Q000009:adverse effects; D000932:Antiemetics / Q000627:therapeutic use*; D003907:Dexamethasone / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008787:Metoclopramide / Q000627:therapeutic use; D017294:Ondansetron / Q000627:therapeutic use; D020250:Postoperative Nausea and Vomiting / Q000453:epidemiology / Q000517:prevention & control*; D011292:Premedication / Q000706:statistics & numerical data*; D011398:Promethazine / Q000627:therapeutic use; D011446:Prospective Studies; D019651:Plastic Surgery Procedures / Q000009:adverse effects* / Q000706:statistics & numerical data; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000932:Antiemetics; D017294:Ondansetron; D003907:Dexamethasone; D011398:Promethazine; D008787:Metoclopramide