[Research on active constituents research of gualou xiebai baijiutang (III). The active flavanoids].
OBJECTIVE
To observe the substance basis of actions of Gualou xiebai baijiutang.


METHODS
Guided by bioactivities, the prescription was isolated and purified by chemical and chromatographic methods, and the structures were identified by chemical and spectral methods.


RESULTS
4 compounds were isolated from active parts.


CONCLUSIONS
3 compounds were isolated for the first time from Trichosanthes kirilowii and Allium macrostemon. Compound 1 had a good activity against platelet aggregation.
He
Xiang-jiu
XJ
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning, China.
Wang
Nai-li
NL
Qiu
Feng
F
Yao
Xin-sheng
XS
D000490:Allium / Q000737:chemistry; D000818:Animals; D004187:Disaccharides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000431:Ethanol; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D010974:Platelet Aggregation / Q000187:drug effects; D011794:Quercetin / Q000302:isolation & purification; D051381:Rats; D029778:Trichosanthes / Q000737:chemistry
C488005:3',5-dihydroxy-4'-methoxyflavone-7-O-rhamnosyl-1-6-glucoside; D004187:Disaccharides; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; C488004:gualou xiebai baijiutang; D000431:Ethanol; D011794:Quercetin