title: Investigation of intermolecular interaction in molecular complex of tryptamine and benzoic acid by solid-state 2D NMR.
abstract: Solid-state NMR spectra and powder X-ray diffraction of the two-component molecular complex composed of tryptamine and benzoic acid were observed to investigate the intermolecular interaction in the molecular complex. 1D (13)C CP/MAS NMR spectrum and powder X-ray diffraction pattern of the complex was clearly different from the convolution of each spectrum of the single component. 2D (1)H-(13)C heteronuclear-correlation (HETCOR) NMR technique indicated that the intermolecular interaction between the primary amine of tryptamine and the carboxyl group of benzoic acid must be related to the complex formation.
authors.affiliation: Analytical Development Laboratories, Takeda Chemical Industries, Ltd., Osaka, Japan. Terakita_Akira@takeda.co.jp
authors.forename: Akira
authors.initials: A
authors.lastname: Terakita
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Matsunaga
authors.forename: Takahiro
authors.initials: T
authors.lastname: Ueda
authors.forename: Taro
authors.initials: T
authors.lastname: Eguchi
authors.forename: Midori
authors.initials: M
authors.lastname: Echigoya
authors.forename: Kazuichi
authors.initials: K
authors.lastname: Umemoto
authors.forename: Masayuki
authors.initials: M
authors.lastname: Godo
mesh_terms: D019817:Benzoic Acid / Q000032:analysis* / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D014363:Tryptamines / Q000032:analysis* / Q000737:chemistry*
chemical_list: D014363:Tryptamines; C030820:tryptamine; D019817:Benzoic Acid