Anticonvulsants as anxiolytics, part 2: Pregabalin and gabapentin as alpha(2)delta ligands at voltage-gated calcium channels.
Stahl
Stephen M
SM
Neuroscience Education Institute, 5857 Owens Street, Suite 102, Carlsbad, CA 92009, USA.
D000085:Acetates / Q000494:pharmacology* / Q000627:therapeutic use; D000588:Amines; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D000927:Anticonvulsants / Q000494:pharmacology* / Q000627:therapeutic use; D001008:Anxiety Disorders / Q000188:drug therapy; D015220:Calcium Channels / Q000187:drug effects* / Q000502:physiology; D003509:Cyclohexanecarboxylic Acids; D005239:Fear / Q000187:drug effects / Q000502:physiology; D000077206:Gabapentin; D006801:Humans; D015640:Ion Channel Gating / Q000187:drug effects; D008024:Ligands; D000069583:Pregabalin; D009435:Synaptic Transmission / Q000187:drug effects / Q000502:physiology; D005680:gamma-Aminobutyric Acid / Q000031:analogs & derivatives* / Q000494:pharmacology* / Q000627:therapeutic use
D000085:Acetates; D000588:Amines; D014151:Anti-Anxiety Agents; D000927:Anticonvulsants; C425903:CACNA2D1 protein, human; D015220:Calcium Channels; D003509:Cyclohexanecarboxylic Acids; D008024:Ligands; D000069583:Pregabalin; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin