title: Serum immunoglobulins and IgG subclass levels in sinus mycetoma.
abstract: OBJECTIVE
  To study the immunity of patients with sinus mycetoma by measuring serum immunoglobulins and IgG subclass levels.
  
  
  METHODS
  Thirty patients with sinus mycetoma, 71 ordinary chronic rhinosinusitis patients without nasal polyps, and 77 ordinary chronic rhinosinusitis patients with nasal polyps were collected. In all subjects, the levels of total serum immunoglobulins and IgG subclasses were measured during surgical treatment.
  
  
  RESULTS
  Among 30 patients with sinus mycetoma, decreased IgA level was found in 1 patient, and decreased IgM level was found in another 2 patients. There were no significant differences in the levels of total serum immunoglobulins or IgG subclasses between patients with sinus mycetoma and ordinary chronic rhinosinusitis patients with or without nasal polyps.
  
  
  CONCLUSIONS
  Immunologic defects cannot be detected in patients with sinus mycetoma by measuring levels of total serum immunoglobulins or IgG subclasses.
  
  
  CONCLUSIONS
  Immunoglobulin deficiency may not play an important role in the pathogenesis of sinus mycetoma.
authors.affiliation: Department of Otolaryngology, Taichung Veterans General Hospital, Taiwan, Republic of China. rsjiang@vghtc.vghtc.gov.tw
authors.forename: Rong-San
authors.initials: RS
authors.lastname: Jiang
authors.forename: Chen-Yi
authors.initials: CY
authors.lastname: Hsu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000097:blood*; D020461:Madurella; D008297:Male; D008875:Middle Aged; D008271:Mycetoma / Q000276:immunology*; D009298:Nasal Polyps / Q000150:complications / Q000276:immunology*; D011446:Prospective Studies; D012852:Sinusitis / Q000150:complications / Q000276:immunology* / Q000382:microbiology*
chemical_list: D007136:Immunoglobulins