Interstitial pneumonia and hepatitis caused by minocycline.
A 28-year-old patient is described who presented with progressive dyspnoea and jaundice due to interstitial pneumonia and hepatitis. The most likely cause is a drug-related reaction to minocycline. We discuss the different kinds of drug-related reactions that are most likely involved.
Rikken
N E T
NE
Department of Internal Medicine, Maxima Medical Centre, Eindhoven, The Netherlands. n.rikken@elisabeth.nl
Klinkhamer
P J J M
PJ
Haak
H R
HR
D000152:Acne Vulgaris / Q000188:drug therapy; D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000000981:diagnostic imaging / Q000209:etiology*; D004417:Dyspnea / Q000139:chemically induced / Q000000981:diagnostic imaging; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000139:chemically induced* / Q000000981:diagnostic imaging; D008297:Male; D008911:Minocycline / Q000009:adverse effects*; D013902:Radiography, Thoracic
D000900:Anti-Bacterial Agents; D008911:Minocycline