[Thoracic aspergillosis: indications for surgery for a multifaceted disease!].
We reviewed the different clinical forms of thoracic aspergillosis and detailed surgical options. Classical aspergiloma where a tuft of Aspergillus grows in a parenchymal cavity is the most well-known entity. Simple forms (little clinical expression, thin-walled cavity without impact on neighboring tIssue) can be distinguished from complex forms (poor general status, thickened cavity, sequellae). Surgery is the last resort for complex forms, but the procedure is benign for simple forms allowing interruption of the spontaneous evolution. Pleural aspergillosis is a common complication of the excision procedure, whether performed early or at mid-term. Thoracoplasty is often required due to the Volume of parenchyma removed. Surgery can be proposed for acute invasive aspergillosis in two situations: to prevent cataclysmic hemoptysis due to a paravascular lesion, or for resection of sequestered mycotic deposits which could lead to generalized reinfection. Semi-invasive aspergillosis is usually observed in areas of post-radiation fibrosis where the typical aspergillar excavation appears after the initial phase of invasion leading to lobular pneumonia. Thoracoplasty is often the only surgical option. Ulcerated aspergillar tracheobronchitis is observed after (heart)-lung transplantation and raises the risk of characteristic invasive aspergillosis. Finally rare observations of parietal aspergillosis have been treated by surgical resection in combination with systemic antifungal agents. Multidisciplinary consultation is required to establish the most appropriate approach.
Massard
G
G
Service de Chirurgie Thoracique, Hôpitaux Universitaires de Strasbourg, 67091 Strasbourg. Gilbert.Massard@chru-strasbourg.fr
D001228:Aspergillosis / Q000473:pathology / Q000601:surgery*; D006469:Hemoptysis / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D008172:Lung Diseases, Fungal / Q000473:pathology / Q000601:surgery*; D018579:Patient Selection; D010995:Pleural Diseases / Q000382:microbiology / Q000473:pathology / Q000601:surgery*; D011379:Prognosis; D012307:Risk Factors; D013905:Thoracoplasty / Q000379:methods*