Contribution of the RpoA C-terminal domain to stimulation of the Salmonella enterica hilA promoter by HilC and HilD.
Expression of invasion genes in Salmonella pathogenicity island 1 (SPI-1) is mainly driven by the transcriptional activator HilA. Transcription of hilA is subject to complex control and is stimulated by the SPI-1-encoded HilC and HilD proteins. The C-terminal domain of RpoA contributes to hilA activation by HilC/D under certain inducing conditions.
Olekhnovich
Igor N
IN
Department of Microbiology, University of Virginia School of Medicine, Charlottesville, Virginia 22908-0734, USA.
Kadner
Robert J
RJ
D001426:Bacterial Proteins / Q000502:physiology*; D001665:Binding Sites; D012321:DNA-Directed RNA Polymerases / Q000737:chemistry* / Q000502:physiology; D015964:Gene Expression Regulation, Bacterial; D011401:Promoter Regions, Genetic; D019779:Salmonella enterica / Q000235:genetics*; D015534:Trans-Activators / Q000235:genetics*; D014157:Transcription Factors / Q000502:physiology*; D014158:Transcription, Genetic
D001426:Bacterial Proteins; C102236:HilA protein, Salmonella; C119659:HilC protein, Salmonella typhimurium; C119660:HilD protein, Salmonella typhimurium; D015534:Trans-Activators; D014157:Transcription Factors; D012321:DNA-Directed RNA Polymerases; C113275:RNA polymerase alpha subunit