Metastatic mesothelioma presenting with proptosis.
OBJECTIVE
To describe the clinical presentation and histologic findings in a patient with metastatic mesothelioma presenting to the ophthalmologist with nonaxial proptosis.


METHODS
Case report.


METHODS
A 55-year-old man presented with a short history of progressive ocular discomfort and vertical diplopia. Clinical examination identified nonaxial proptosis. Subsequent computed tomography showed a large extraconal mass consistent with a malignant process. Three months earlier the patient had been diagnosed with pleural mesothelioma. Unfortunately, he died 3 months after his ophthalmic presentation. Postmortem examination confirmed metastatic mesothelioma in the orbital roof that was histologically identical to the primary pleural malignancy.


CONCLUSIONS
Pleural mesothelioma can metastasize to the orbit, causing proptosis.
Gibson
Andrew
A
Prince Charles Eye Unit, King Edward VII Hospital, Windsor, United Kingdom. agibson@tinyonline.co.uk
Musa
Fawaz
F
Pearson
Andrew
A
Wiggins
John
J
D014408:Biomarkers, Tumor / Q000032:analysis; D005094:Exophthalmos / Q000175:diagnosis*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000737:chemistry / Q000000981:diagnostic imaging / Q000556:secondary*; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging / Q000556:secondary*; D010997:Pleural Neoplasms / Q000737:chemistry / Q000473:pathology*; D014057:Tomography, X-Ray Computed
D014408:Biomarkers, Tumor