Benign renal mesenchymoma in the pediatric age group: a novel pathologic and karyotype entity.
Benign mesenchymal renal tumors are extremely rare in the pediatric age group. We report a case of a benign renal tumor composed of smooth muscle cells, adipose tissue, and areas of cartilaginous differentiation and expressing a 46,XX, t(8;10)(q21;q24) karyotype in a 13-year-old girl. Although some pediatric renal tumors show a degree of heterologous differentiation, none of them exclusively consist of these three well-differentiated mesenchymal components. The unique features of the present case were further confirmed by the karyotype changes, which to our knowledge, have never been described before in a pediatric renal tumor.
Joniau
Steven
S
Department of Urology, University Hospitals Leuven, Leuven, Belgium.
Goeman
Lieven
L
Kreuzbauer
Susanne
S
Bogaert
Guy
G
Dal Cin
Paola
P
Oyen
Raymond
R
Sciot
Raf
R
van Poppel
Hein
H
D000293:Adolescent; D001064:Appendicitis / Q000601:surgery; D005260:Female; D006801:Humans; D033162:Incidental Findings; D007621:Karyotyping; D007680:Kidney Neoplasms / Q000235:genetics / Q000473:pathology*; D008637:Mesenchymoma / Q000235:genetics / Q000473:pathology*