SNPCEQer II: the integrated detection and analysis of SNPs in DNA sequences.
SNPCEQer II is a graphical user interface (GUI)-based application that integrates single nucleotide polymorphism (SNP) detection, SNP analysis and SNP editing in the Microsoft Windows (R) environment. SNPCEQer II detects SNPs in DNA sequences generated by the Beckman CEQ TM 2000 XL DNA analysis system. It provides tools to analyse SNPs by inspecting and comparing trace data (chromatograms) around putative SNPs with that of other related DNA sequences, and it can search for those SNPs in the National Center for Biotechnology Information (NCBI) databases. SNPCEQer II can determine the mutation type of a coding SNP and generate data for submission to the dbSNP database. The SNP report can be edited and printed, as can the chromatograms. SNPCEQer II is implemented in Visual C++.
Tang
Fuqiang
F
Eugene McDermott Center for Human Growth and Development, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Flood
Elizabeth M
EM
Pertsemlidis
Alexander
A
Garner
Harold R
HR
D000465:Algorithms; D003628:Database Management Systems; D030541:Databases, Genetic; D019075:Electrophoresis, Capillary / Q000295:instrumentation / Q000379:methods; D016247:Information Storage and Retrieval / Q000379:methods; D009317:National Library of Medicine (U.S.); D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D016415:Sequence Alignment / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000295:instrumentation* / Q000379:methods*; D012984:Software; D018511:Systems Integration; D014481:United States; D014584:User-Computer Interface