title: Artificial liver support molecular adsorbents recirculating system therapy as a bridge to re-transplantation in two cases of long anhepatic duration.
abstract: BACKGROUND
  Molecular adsorbents recirculating system (MARS) liver support therapy is the development of albumin dialysis. This study was to assess the successful application of MARS artificial liver support therapy as a bridge to re-transplantation in two cases of long anhepatic duration.
  
  
  METHODS
  MARS therapy was given after failure plasma-exchange (PE) treatment, which resulted in circulatory derangement and acute renal dysfunction in a 36-year-old male patient. Finally his uncontrolled anhepatic condition led to a successful re-transplantation. In another 48-year-old man who was diagnosed as having primary nonfunction (PNF) during the liver transplantation, 10-hour MARS treatment contributed to smooth bridging of his anhepatic phase.
  
  
  RESULTS
  The two anhepatic patients were bridged for 26 and 17 hours respectively to re-transplantation with MARS therapy.
  
  
  CONCLUSIONS
  Our experience proves that MARS artificial liver can be an effective support for long time bridging PNF until re-transplantation is available.
authors.affiliation: Tianjin Organ Transplantation Institute, Tianjin First Central Hospital, Tianjin 300192, China.
authors.forename: Yi-He
authors.initials: YH
authors.lastname: Liu
authors.forename: Yu
authors.initials: Y
authors.lastname: Wang
authors.forename: Li-Xin
authors.initials: LX
authors.lastname: Yu
authors.forename: Li-Ying
authors.initials: LY
authors.lastname: Sun
authors.forename: Bao-Lan
authors.initials: BL
authors.lastname: Feng
authors.forename: Zhong-Yang
authors.initials: ZY
authors.lastname: Shen
authors.forename: Min-Min
authors.initials: MM
authors.lastname: Wang
mesh_terms: D000328:Adult; D006801:Humans; D017093:Liver Failure / Q000209:etiology* / Q000601:surgery / Q000628:therapy*; D016031:Liver Transplantation / Q000009:adverse effects*; D019164:Liver, Artificial; D008297:Male; D008875:Middle Aged; D012086:Reoperation; D013997:Time Factors; D016896:Treatment Outcome