Lost in translation gets an oskar.
Nuclear history affects the fates of mRNAs in the cytoplasm of cells. Proteins loaded onto mRNAs in the nucleus mark RNAs for subsequent translational regulation, stability, degradation, and subcellular RNA localization. New results show that the Drosophila heterogeneous nuclear ribonucleoprotein (hnRNP) Hrp48 contributes to coordinated RNA localization and translational control in oocytes.
Hazelrigg
Tulle
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Department of Biological Sciences, Sherman Fairchild Center, Columbia University, New York, NY 10027, USA.
D000818:Animals; D029721:Drosophila Proteins / Q000378:metabolism; D034441:Heterogeneous-Nuclear Ribonucleoproteins / Q000378:metabolism; D009865:Oocytes / Q000166:cytology / Q000378:metabolism; D009866:Oogenesis / Q000235:genetics; D014176:Protein Biosynthesis / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics; D016211:Transforming Growth Factor alpha / Q000378:metabolism
D029721:Drosophila Proteins; C083730:grk protein, Drosophila; D034441:Heterogeneous-Nuclear Ribonucleoproteins; C091675:osk protein, Drosophila; D012333:RNA, Messenger; D016211:Transforming Growth Factor alpha