title: CFD simulation of centrifugal cells washers.
abstract: The feasibility of using computational fluid dynamics to guide the design of better centrifuges for processing shed blood is explored here. The velocity field and the rate of protein removal from the shed blood have been studied. The results indicate that computational fluid dynamics could help screen preliminary centrifuge bowl designs thus reducing the number of initial experimental tests required when developing new centrifuge bowls. Though the focus of this work is on washing shed blood the methods developed here are applicable to the design of centrifuge bowls for other blood processing applications.
authors.affiliation: Department of Chemical Engineering, Colorado State University, Fort Collins, CO 80523, USA.
authors.forename: Beth E
authors.initials: BE
authors.lastname: Kellet
authors.forename: Han
authors.initials: H
authors.lastname: Binbing
authors.forename: David S
authors.initials: DS
authors.lastname: Dandy
authors.forename: S Ranil
authors.initials: SR
authors.lastname: Wickramasinghe
mesh_terms: D001773:Blood Cells / Q000166:cytology*; D001798:Blood Proteins / Q000302:isolation & purification*; D002469:Cell Separation / Q000295:instrumentation / Q000379:methods*; D002498:Centrifugation / Q000295:instrumentation* / Q000379:methods*; D003198:Computer Simulation; D017076:Computer-Aided Design; D004867:Equipment Design / Q000379:methods*; D019544:Equipment Failure Analysis / Q000379:methods; D006440:Hemofiltration / Q000295:instrumentation / Q000379:methods; D018056:Hemorheology / Q000379:methods; D008955:Models, Cardiovascular
chemical_list: D001798:Blood Proteins