title: [Lymphatic mapping and inguinal sentinel lymph node biopsy in anal canal cancers to avoid prophylactic inguinal irradiation].
abstract: Thirty-five patients with clinically N0 cancers of the canal anal, 33 epidermoid carcinomas et 2 melanomas were histologically staged with inguinal sentinel lymph node biopsy (ISN). With the combined technique, blue dye and radiocolloid the ISN was identified in 100% of the cases. The ISN was invaded in 7 cases/33 for epidermoid tumors and 2/2 for melanomas. After 18 months of follow-up, no inguinal recurrence could be seen in ISN pN0 cases. In conclusion, ISN biopsy is a reliable procedure to stage anal canal cancers. It should prevent unnecessary prophylactic inguinal irradiation for pN0 ISN. Inguinal irradiation is only indicated in pN1 ISN.
authors.affiliation: Service de chirurgie oncologique, centre hospitalier Lyon-Sud, 69496 Pierre-Bénite, France. service.bobin@chu-lyon.fr
authors.forename: J Y
authors.initials: JY
authors.lastname: Bobin
authors.forename: J P
authors.initials: JP
authors.lastname: Gérard
authors.forename: O
authors.initials: O
authors.lastname: Chapet
authors.forename: P
authors.initials: P
authors.lastname: Romestaing
authors.forename: S
authors.initials: S
authors.lastname: Isaac
mesh_terms: D000328:Adult; D000368:Aged; D001005:Anus Neoplasms / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007264:Inguinal Canal; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008545:Melanoma / Q000473:pathology*; D008875:Middle Aged; D009367:Neoplasm Staging; D011877:Radionuclide Imaging; D012307:Risk Factors; D021701:Sentinel Lymph Node Biopsy / Q000379:methods; D013997:Time Factors; D014463:Ultrasonography