Application of combined magnetic resonance imaging and histopathologic and functional studies for evaluation of aminoguanidine following traumatic brain injury in rats.
Lu
Jia
J
Defence Medical Research Institute, Singapore.
Moochhala
Shabbir
S
D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D001921:Brain / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology; D001923:Brain Chemistry; D001930:Brain Injuries / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D053148:Caspase 3; D020169:Caspases / Q000032:analysis; D004791:Enzyme Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D005552:Forelimb / Q000187:drug effects / Q000503:physiopathology; D006146:Guanidines / Q000494:pharmacology* / Q000627:therapeutic use; D007150:Immunohistochemistry; D020287:In Situ Nick-End Labeling; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D009048:Motor Skills / Q000187:drug effects; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors; D010477:Perfusion; D011312:Pressure; D011597:Psychomotor Performance / Q000187:drug effects; D051381:Rats; D017207:Rats, Sprague-Dawley; D013216:Reflex, Startle / Q000187:drug effects; D012965:Sodium Chloride / Q000008:administration & dosage / Q000494:pharmacology; D016707:Tissue Fixation
D004791:Enzyme Inhibitors; D006146:Guanidines; D012965:Sodium Chloride; D019001:Nitric Oxide Synthase; C505410:Casp3 protein, rat; D053148:Caspase 3; D020169:Caspases; C004479:pimagedine