title: Understanding diseases via receptor regulation.
abstract: In this issue of Chemistry & Biology, Guy and coworkers demonstrate that they can selectively recruit individual nuclear receptors by using small molecules (proteomimetics) in combination with specific agonists. This may ultimately lead to a link between the receptor's signaling pathway and its role in individual diseases.
authors.affiliation: Department of Chemistry, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182, USA.
authors.forename: Shelli R
authors.initials: SR
authors.lastname: McAlpine
mesh_terms: D000494:Allosteric Regulation; D000818:Animals; D008024:Ligands; D008659:Metabolic Diseases / Q000235:genetics / Q000378:metabolism; D009369:Neoplasms / Q000235:genetics / Q000378:metabolism; D040901:Proteomics; D018160:Receptors, Cytoplasmic and Nuclear / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D008024:Ligands; D018160:Receptors, Cytoplasmic and Nuclear