[Collagen changes of allografting an acellular dermal matrix].
OBJECTIVE
To evaluate the collagen changes of allografting an acellular dermal matrix (allo-ADM).


METHODS
The allo-ADM was grafted underneath the skin of SD rats. The content of collagen and the proportion of type I to III collagen was examined with a biochemical assay.


RESULTS
The content of collagen and the proportion of type I to III collagen in the allo-ADM group showed no significant changes.


CONCLUSIONS
The allo-ADM could keep long time in the body and it may be an ideal material for soft tissue filling.
Huo
Meng-hua
MH
Plastic Surgery Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100041, China.
Qi
Ke-ming
KM
Huang
Jin-jing
JJ
Guan
Zheng-yu
ZY
Zhuang
Qiang
Q
Wang
Yang
Y
Lü
Xiao-Yan
XY
D000818:Animals; D003094:Collagen / Q000032:analysis*; D020405:Dermis / Q000378:metabolism / Q000637:transplantation; D005260:Female; D008297:Male; D011184:Postoperative Period; D051381:Rats; D017207:Rats, Sprague-Dawley; D016038:Skin Transplantation / Q000379:methods*; D014184:Transplantation, Homologous
D003094:Collagen