Malaria genome project and its impact on the disease.
Malaria remains uncontrolled to-date due to lack of effective parasite and vector control strategies. With the completion of the host, parasite and vector genome projects more suitable and effective disease control measures can be achieved. Here we have reviewed the Plasmodium falciparum genome project and its impact on malaria research in future. The parasite genome project has revealed certain metabolic pathways which can be targeted to develop antimalarial drugs. It has also identified large number of potential antigens for the future potential vaccines. Now the researchers in the malaria field can plan to take up the studies, which can yield more fruitful results within the limited financial resources using bioinformatics, proteomics, structural, functional and comparative genomics, etc.
Verma
Poonam
P
Department of Biotechnology, All India Institute of Medical Sciences, New Delhi, India.
Sharma
Y D
YD
D000818:Animals; D000852:Anopheles / Q000235:genetics*; D000962:Antimalarials; D018503:Genome, Protozoan; D017780:Malaria Vaccines; D016778:Malaria, Falciparum / Q000469:parasitology* / Q000517:prevention & control; D010963:Plasmodium falciparum / Q000235:genetics*
D000962:Antimalarials; D017780:Malaria Vaccines