title: Prenatal screening for birth defects: an update.
abstract: This article summarizes current second trimester prenatal screening methods, and describes recently developed first trimester screening tools. The advantages and potential pitfalls of first trimester screening are outlined.
authors.affiliation: Department of Pediatrics, Saint Louis University School of Medicine, USA.
authors.forename: Kathy
authors.initials: K
authors.lastname: Morris
mesh_terms: D000013:Congenital Abnormalities / Q000175:diagnosis / Q000235:genetics; D004314:Down Syndrome / Q000175:diagnosis*; D005260:Female; D005820:Genetic Testing; D006801:Humans; D011237:Predictive Value of Tests; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D011296:Prenatal Diagnosis / Q000379:methods*; D016216:Ultrasonography, Prenatal / Q000639:trends*