Gastrointestinal bleeding after the introduction of COX 2 inhibitors: ecological study.
Mamdani
Muhammad
M
Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G106, Toronto, ON, Canada M4N 3M5. muhammad.mamdani@ices.on.ca
Juurlink
David N
DN
Kopp
Alex
A
Naglie
Gary
G
Austin
Peter C
PC
Laupacis
Andreas
A
D000367:Age Factors; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D003430:Cross-Sectional Studies; D051546:Cyclooxygenase 2; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors / Q000009:adverse effects*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced* / Q000453:epidemiology; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors*; D008297:Male; D008565:Membrane Proteins; D009864:Ontario / Q000453:epidemiology; D015995:Prevalence; D011451:Prostaglandin-Endoperoxide Synthases; D012307:Risk Factors; D012737:Sex Factors
D000894:Anti-Inflammatory Agents, Non-Steroidal; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D007527:Isoenzymes; D008565:Membrane Proteins; D051546:Cyclooxygenase 2; C496540:PTGS2 protein, human; D011451:Prostaglandin-Endoperoxide Synthases