title: Clivus lymphoma.
abstract: Lymphoma as primary infiltration of the skull base, especially the clivus, is unusual and rare. However, increasing incidence of atypical lymphoma manifestations have been reported. As cranial base surgery becomes more common, it is important to be aware of lymphoma as a possible differential diagnosis of clivus lesions. This case presents a primary malignant lymphoma of the clivus, histologically confirmed after intra-operative MRI-guided transnasal-transsphenoidal biopsy.
authors.affiliation: Department of Neurosurgery, Johann-Wolfgang Goethe University, Frankfurt, Germany. c.s.jung@em.uni-frankfurt.de
authors.forename: C S
authors.initials: CS
authors.lastname: Jung
authors.forename: M
authors.initials: M
authors.lastname: Zimmermann
authors.forename: V
authors.initials: V
authors.lastname: Seifert
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003388:Cranial Fossa, Posterior / Q000473:pathology*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000188:drug therapy / Q000473:pathology*; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D019292:Skull Base Neoplasms / Q000188:drug therapy / Q000473:pathology*; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone