Management of long-term catheter-related Brevibacterium bacteraemia.
Brevibacterium has been reported as a rare cause of implanted-device infection. In two cases of recurrent Brevibacterium casei bacteraemia associated with infection of surgically implanted intravascular devices, relapse occurred 2 and 5 months, respectively, after completion of therapy with vancomycin via the infected catheter. A second intravenous antibiotic therapy course by the antibiotic-lock technique led to bacteriological cure in one patient. Molecular typing results demonstrated that the recurrent bacteraemia was caused by the same strain. Implanted-device removal may be necessary, in addition to appropriate antibiotics, for successful management of such infections.
Beukinga
I
I
Department of Microbiology, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium.
Rodriguez-Villalobos
H
H
Deplano
A
A
Jacobs
F
F
Struelens
M J
MJ
D000193:Actinomycetales Infections / Q000188:drug therapy / Q000382:microbiology / Q000628:therapy*; D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology / Q000628:therapy*; D001951:Brevibacterium / Q000187:drug effects; D002408:Catheters, Indwelling / Q000382:microbiology*; D020878:Device Removal; D004866:Equipment Contamination; D005260:Female; D006801:Humans; D008297:Male; D014640:Vancomycin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D014640:Vancomycin