[The similarities and the differences of embryogenesis and carcinogenesis].
The main similarities and embryonic and tumor cells, as well as the mechanisms preventing the malignant transformation of embryonic cells, are presented in this review. Special attention is paid to the role of specific polypeptide growth factors in reciprocally excluding processes: embryogenesis and carcinogenesis. Based on the presented analysis, new potential targets for antitumor drugs are considered.
Stoĭka
R S
RS
Institute of Cell Biology, National Academy of Sciences of Ukraine, Ivan Franko Lviv National University, 79005 Ukraine.
Panchuk
R R
RR
Stoĭka
B R
BR
D000818:Animals; D000941:Antigens / Q000378:metabolism; D017209:Apoptosis; D002448:Cell Adhesion / Q000502:physiology; D002454:Cell Differentiation; D049109:Cell Proliferation; D004622:Embryo, Mammalian / Q000166:cytology / Q000276:immunology / Q000502:physiology*; D047108:Embryonic Development; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000502:physiology; D009361:Neoplasm Invasiveness; D009369:Neoplasms / Q000209:etiology* / Q000473:pathology*; D009389:Neovascularization, Pathologic; D018919:Neovascularization, Physiologic; D011247:Pregnancy
D000941:Antigens