title: Merogony of Toxoplasma gondii (Apicomplexa: Coccidia) and its effect on the mortality and histopathology in the house mouse Mus musculus.
abstract: Merogonic stages of Toxoplasma gondii, their effects on the mortality and histopathological changes in the orally-inoculated male house mice Mus musculus with low and high doses (LD&HD) of T. gondii sporulated oocysts was investigated. The mortality percentage in LD group was 16%, 20%, 28% and 72%, while that in HD group was 36%, 56%, 72% and 100% in the 1st-4th week, respectively. Meanwhile, the maximum mortality percentage of the control group reached 6%. The histopathological changes induced by the parasite in different organs such as kidneys, liver, brain, spleen, heart, lungs and testes were discussed.
authors.affiliation: Department of Zoology, Faculty of Science, Cairo University, Egypt.
authors.forename: Hamed M
authors.initials: HM
authors.lastname: Fayed
authors.forename: Kamilia A M
authors.initials: KA
authors.lastname: Allam
authors.forename: Nour-Eldin Shams-Eldin
authors.initials: NE
authors.lastname: Ali
mesh_terms: D000818:Animals; D001921:Brain / Q000469:parasitology / Q000473:pathology; D006321:Heart / Q000469:parasitology; D007668:Kidney / Q000469:parasitology / Q000473:pathology; D007928:Lethal Dose 50; D008099:Liver / Q000469:parasitology / Q000473:pathology; D008168:Lung / Q000469:parasitology / Q000473:pathology; D008297:Male; D051379:Mice; D033661:Oocysts; D011897:Random Allocation; D013154:Spleen / Q000469:parasitology / Q000473:pathology; D013737:Testis / Q000469:parasitology / Q000473:pathology; D014122:Toxoplasma / Q000472:pathogenicity*; D014124:Toxoplasmosis, Animal / Q000401:mortality* / Q000473:pathology