Quantifying arbitrary magnetic susceptibility distributions with MR.
Magnetic susceptibility, as a physical property of materials, plays important roles in many physical, chemical, engineering, and medical applications. Its quantification becomes of significant interest when MRI becomes a commonly used technique in biomedical applications. A general method is presented here for quantifying arbitrary magnetic susceptibility distributions in a localized region on the basis of first principles of magnetic induction field distributions in space. A proof of the concept was demonstrated by computer simulations. The study establishes the methodological basis for quantitative magnetic susceptibility imaging with MR.
Li
Lin
L
Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. lin@mail.mmrrcc.upenn.edu
Leigh
John S
JS
D003198:Computer Simulation; D008279:Magnetic Resonance Imaging; D008280:Magnetics; D008962:Models, Theoretical