title: Effects of moxibustion at shenque (CV 8) on serum IL-12 level and NK cell activities in mice with transplanted tumor.
abstract: The study was to investigate the effect of moxibustion on the serum IL-2, IL-12 levels and NK cell and ascitic tumor cell activities in H-22 mice with tumor and its mechanisms. The method used in the study was that the IL-2 and IL-12 levels were determined by the double antibody method with ELISA, and the NK cell activities by the MTT measure. The results showed that moxibustion elevated the serum IL-2 and IL-12 levels and the NK cell activities of the mice with tumor, and the elevations were of significance as compared with the controls (P < 0.05). It is concluded that moxibustion can inhibit the growth of tumor, which is related to the increase of the serum IL-2 and IL-12 levels and the strengthening of NK cell activities.
authors.affiliation: Nanfang Hospital, First Military Medical University, Guangzhou 510515, Guangdong Province.
authors.forename: Xingsheng
authors.initials: X
authors.lastname: Qiu
authors.forename: Kai
authors.initials: K
authors.lastname: Chen
authors.forename: Li
authors.initials: L
authors.lastname: Tong
authors.forename: Xiaoliang
authors.initials: X
authors.lastname: Shu
authors.forename: Xinzhi
authors.initials: X
authors.lastname: Lü
authors.forename: Hanping
authors.initials: H
authors.lastname: Wen
authors.forename: Chunhua
authors.initials: C
authors.lastname: Deng
mesh_terms: D015669:Acupuncture Points; D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000097:blood / Q000276:immunology*; D018664:Interleukin-12 / Q000097:blood*; D007376:Interleukin-2 / Q000097:blood; D007694:Killer Cells, Natural / Q000276:immunology*; D051379:Mice; D009071:Moxibustion; D009368:Neoplasm Transplantation
chemical_list: D007376:Interleukin-2; D018664:Interleukin-12