The mitochondrial ribosome of the protozoan Acanthamoeba castellanii is the target for macrolide antibiotics.
Mathis
Alexander
A
Institute of Parasitology, University of Zürich, Winterthurerstrasse 266A, 8057 Zürich, Switzerland. alexander.mathis@access.unizh.ch
Wild
Peter
P
Deplazes
Peter
P
Boettger
Erik C
EC
D000048:Acanthamoeba / Q000187:drug effects*; D000818:Animals; D017291:Clarithromycin / Q000494:pharmacology; D005839:Gentamicins / Q000494:pharmacology; D006921:Hygromycin B / Q000494:pharmacology; D018942:Macrolides / Q000494:pharmacology*; D008854:Microscopy, Electron; D008928:Mitochondria / Q000187:drug effects* / Q000648:ultrastructure; D012270:Ribosomes / Q000187:drug effects* / Q000648:ultrastructure
D005839:Gentamicins; D018942:Macrolides; D006921:Hygromycin B; D017291:Clarithromycin