title: Improved outcome of polyoma virus allograft nephropathy with early biopsy.
abstract: Polyoma virus allograft nephropathy often results in accelerated graft loss despite reduction of immunosuppression and/or treatment with antiviral agents. Irreversible renal fibrosis due to late diagnosis is likely to be one of the important causes of treatment failure. Early biopsy in 14 patients resulted in stable graft function after a mean follow-up of 22 months.
authors.affiliation: Pathology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
authors.forename: C B
authors.initials: CB
authors.lastname: Drachenberg
authors.forename: J C
authors.initials: JC
authors.lastname: Papadimitriou
authors.forename: R
authors.initials: R
authors.lastname: Wali
authors.forename: J
authors.initials: J
authors.lastname: Nogueira
authors.forename: S
authors.initials: S
authors.lastname: Mendley
authors.forename: H H
authors.initials: HH
authors.lastname: Hirsch
authors.forename: C B
authors.initials: CB
authors.lastname: Cangro
authors.forename: D K
authors.initials: DK
authors.lastname: Klassen
authors.forename: M R
authors.initials: MR
authors.lastname: Weir
authors.forename: S T
authors.initials: ST
authors.lastname: Bartlett
authors.forename: E
authors.initials: E
authors.lastname: Ramos
mesh_terms: D001706:Biopsy; D003404:Creatinine / Q000097:blood; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000276:immunology / Q000473:pathology*; D016133:Polymerase Chain Reaction; D011120:Polyomavirus / Q000235:genetics / Q000302:isolation & purification; D027601:Polyomavirus Infections / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D003404:Creatinine