Typical MPGN with few urinary abnormalities.
We describe the concurrent appearance of membranoproliferative glomerulonephritis (MPGN) in renal biopsy samples and normal urinary sediment without hematuria, proteinuria, or renal dysfunction in 1 child and asymptomatic microscopic hematuria without significant proteinuria or renal dysfunction in 2 children who were subsequently followed up for many years. The only other abnormality detected was hypocomplementemia. This is the first report of biopsy-proven typical MPGN in patients with few urinary abnormalities. A renal biopsy should be considered in children with hypocomplementemia, regardless of urinalysis findings, to exclude MPGN.
Yata
Nahoko
N
Department of Nephrology, Tokyo Metropolitan Children's Hospital, Kiyose, Japan. n-yata@wakayama-med.ac.jp
Ikeda
Masahiro
M
Ishikura
Kenji
K
Hataya
Hiroshi
H
Matsuyama
Takeshi
T
Banba
Masahiro
M
Hasegawa
Osamu
O
Honda
Masataka
M
D001706:Biopsy; D002648:Child; D015432:Glomerulonephritis, Membranoproliferative / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D006417:Hematuria / Q000209:etiology; D006801:Humans; D008297:Male; D011507:Proteinuria / Q000209:etiology