title: The outcome of detrusor myotomy in children with neurogenic bladder dysfunction.
abstract: OBJECTIVE
  We evaluate the outcome of detrusor myotomy for neurogenic bladder dysfunction (NBD) in children.
  
  
  METHODS
  A retrospective analysis was performed of data compiled from medical and urodynamic records of children younger than 16 years with NBD who had undergone detrusor myotomy from 1992 to 2000 at our department.
  
  
  RESULTS
  Surgery was performed in 14 children with a mean age +/- SD of 6.7 +/- 4.3 years (range 0.9 to 14.2) and mean followup of 5.9 +/- 1.7 years. All patients were diagnosed with NBD, which was the result of myelomeningocele in 9, sacral agenesis in 2, lumbosacral lipoma in 1, multiple vertebral anomalies in 1 and spinal neuroblastoma in 1. Main indications for surgery included urinary incontinence in 11 cases and high pressure/low capacity bladders with vesicoureteral reflux and impending renal damage in 8. No major postoperative complications were recorded. Although mean maximal cystometric bladder capacity was unchanged 1 month postoperatively (89.7 +/- 70.6 ml) compared to preoperatively (92.5 +/- 75.1 ml, p = 0.87), significant increments of 216%, 237% and 292% were measurable at 3 months, 1 year and 5 years, respectively. Ultimately most of the patients approached age specific capacities. Complete continence on clean intermittent catheterization was achieved by 8 of 11 patients and improved markedly in 1. Reflux was alleviated in 6 cases and improved in 1. Kidney function developed normally in all but 1 patient with persistent reflux.
  
  
  CONCLUSIONS
  When feasible, detrusor myotomy offers a safe and effective alternative for the management of pharmacologically intractable NBD in children.
authors.affiliation: Department of Urology, Aarhus University Hospital-Skejby and The Institute of Experimental Clinical Research, Aarhus University, Aarhus, Denmark. jazcat@dadlnet.dk
authors.forename: Yazan F
authors.initials: YF
authors.lastname: Rawashdeh
authors.forename: Troels M
authors.initials: TM
authors.lastname: Jørgensen
authors.forename: Lars H
authors.initials: LH
authors.lastname: Olsen
authors.forename: Jens C
authors.initials: JC
authors.lastname: Djurhuus
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009130:Muscle, Smooth / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome; D001750:Urinary Bladder, Neurogenic / Q000601:surgery*; D013520:Urologic Surgical Procedures / Q000379:methods