Seafood allergy.
OBJECTIVE
Given the importance and prevalence of seafood in our economy and diet, interest in the adverse effects of seafood-induced allergic reactions has increased both in the lay population and the scientific arena. The purpose for this review article is to provide an overview and discussion of current seafood-allergy research.


RESULTS
Current research has produced the discovery of new seafood allergens as well as a better understanding of the interactions of allergens with the host, and the relationships of IgE antibodies with specific allergens. Crossreactivity of similar molecules from seafood and nonseafood sources provides a better understanding of an allergen's role in seafood allergy and a basis to improve patient identification and treatment.


CONCLUSIONS
Findings in recent literature show potential for more precise diagnosis and safer, more effective treatment of seafood allergies.
Ree-Kim
Linda
L
Section of Allergy and Clinical Immunology, Tulane University School of Medicine, 1700 Perdido Street, New Orleans, LA 70112, USA.
Lehrer
Samuel B
SB
D003429:Cross Reactions / Q000276:immunology; D005512:Food Hypersensitivity / Q000209:etiology / Q000276:immunology* / Q000628:therapy; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D018664:Interleukin-12 / Q000627:therapeutic use; D017747:Seafood / Q000009:adverse effects*
D018664:Interleukin-12; D007073:Immunoglobulin E