title: [Oncologic emergencies associated with pancreatobiliary cancer].
abstract: Clinically common oncologic emergencies associated with pancreatobiliary cancer are gastrointestinal bleeding caused by duodenal invasion of pancreatic carcinoma, severe duodenal obstruction due to pancreatic carcinoma, and acute cholangitis accompanied by obstructive jaundice in patients with biliary tract carcinoma. When a patient with gallbladder cancer presents with acute cholecysitis, emergency surgery is sometimes performed on the basis of the latter diagnosis. Emergency procedures can also be required in the perioperative management of pancreatobiliary cancer, for example, in biliary peritonitis caused by detachment of a percutaneous transhepatic biliary drainage (PTBD) tube and in ruptured pseudoaneurysm due to postoperative pancreatic or biliary leakage. Nonsurgical procedures are usually initially selected for oncologic emergencies associated with pancreatobiliary cancer, because patients are likely to develop severe organ dysfunction and it is difficult to access directly and remove the pancreas or biliary tract during emergency surgery. When systemic conditions improve, it is necessary to evaluate the degree of disease progression and systemic conditions, and if feasible, the primary lesion should be surgically resected. When performing emergency cholecystectomy in patients with acute cholecystitis, thorough intraoperative investigation of resected specimens is important, considering the possibility of concomitant gallbladder carcinoma, since thorough examination cannot be performed in such emergency settings. Furthermore, when cholangitis accompanies pancreatobiliary cancer, emergency drainage should be considered as sepsis can develop rapidly.
authors.affiliation: Department of Surgery I, Iwate Medical University School of Medicine, Morioka, Japan.
authors.forename: Ryoko
authors.initials: R
authors.lastname: Sasaki
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Fujita
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Takeda
authors.forename: Koichi
authors.initials: K
authors.lastname: Hoshikawa
authors.forename: Masahiro
authors.initials: M
authors.lastname: Takahashi
authors.forename: Osamu
authors.initials: O
authors.lastname: Funato
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nitta
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Yaegashi
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Saito
mesh_terms: D000208:Acute Disease; D001650:Bile Duct Neoplasms / Q000150:complications*; D002761:Cholangitis / Q000628:therapy*; D004380:Duodenal Obstruction / Q000628:therapy*; D004630:Emergencies; D006471:Gastrointestinal Hemorrhage / Q000628:therapy*; D006801:Humans; D010190:Pancreatic Neoplasms / Q000150:complications*