Immune cellular response to HPV: current concepts.
Although cellular immunity is essential for the elimination of human papillomavirus (HPV), the mechanisms involved are still poorly understood. We summarize the main mechanisms involved in cellular immune response to infections caused by HPV. Immunotherapies for HPV-related cancers require the disruption of T-cell response control mechanisms, associated with the stimulation of the Th1 cytokine response.
Gonçalves
Maria Alice Guimarães
MA
Clinical Medicine Department, Faculty of Medicine of Ribeirão Prreto, University of São Paulo, São Paulo, Brazil. epigin@uol.com.br
Donadi
Eduardo Antonio
EA
D000938:Antigen-Presenting Cells / Q000276:immunology; D002584:Cervix Uteri / Q000276:immunology / Q000821:virology*; D016207:Cytokines / Q000276:immunology; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D008285:Major Histocompatibility Complex / Q000276:immunology; D027383:Papillomaviridae / Q000276:immunology*; D030361:Papillomavirus Infections / Q000276:immunology*; D014412:Tumor Virus Infections / Q000276:immunology*
D016207:Cytokines