title: Evolutionary genetics: Mobile DNAs as sources of adaptive change?
abstract: Mobile DNAs are potent sources of mutation in wild populations, but seem only rarely to have been used in adaptive evolution. A new study has revealed a mobile DNA insertion in Drosophila simulans that is associated with an apparent selective sweep and an elevation in expression level of an adjacent gene which creates insecticide resistance.
authors.affiliation: Institute of Genetics, University of Nottingham, Queens Medical Centre, Nottingham, NG7 2UH, UK.
authors.forename: John F Y
authors.initials: JF
authors.lastname: Brookfield
mesh_terms: D000220:Adaptation, Biological; D000818:Animals; D004251:DNA Transposable Elements / Q000235:genetics*; D004330:Drosophila; D019143:Evolution, Molecular; D005786:Gene Expression Regulation / Q000235:genetics*; D007305:Insecticide Resistance / Q000235:genetics; D009154:Mutation / Q000235:genetics*; D012641:Selection, Genetic
chemical_list: D004251:DNA Transposable Elements