title: Efficient synthesis of a nucleoside-diphospho-exo-glycal displaying time-dependent inactivation of UDP-galactopyranose mutase.
abstract: A short and efficient synthesis of UDP-exo-galactofuranosyl-glycal is presented. This molecule displayed an interesting time-dependent inactivation of UDP-galactopyranose mutase, an essential enzyme of the mycobacterial cell wall biosynthesis.
authors.affiliation: Ecole Normale Superieure, Departement de Chimie, UMR-8642 du CNRS, 24 rue Lhomond, 75231 Paris Cedex 05, France.
authors.forename: Audrey
authors.initials: A
authors.lastname: Caravano
authors.forename: Stéphane P
authors.initials: SP
authors.lastname: Vincent
authors.forename: Pierre
authors.initials: P
authors.lastname: Sinaÿ
mesh_terms: D004789:Enzyme Activation / Q000502:physiology; D019751:Intramolecular Transferases / Q000378:metabolism*; D009705:Nucleosides / Q000096:biosynthesis*; D013997:Time Factors
chemical_list: D009705:Nucleosides; D019751:Intramolecular Transferases; C098051:UDP-galactopyranose mutase