Incorporation of fluorescent probes into PAMAM dendrimers.
Interactions of two fluorescent probes 1-(trimethylammoniumphenyl)-6-phenyl-1,3,5 hexatriene p-toluenesulfonate (TMA-DPH) and 12-(9-anthroyloxy) stearic acid (12-AS) with polyamidoamine (PAMAM) dendrimers were studied. Changes in fluorescence intensity and steady-state fluorescence anisotropy of TMA-DPH and 12-AS were monitored. It was found that 12-AS molecules incorporated into dendrimer cavities whereas TMA-DPH molecules aggregated on the surface of polymer. Dendrimer size had not significant impact on its host properties.
Domański
D M
DM
Department of General Biophysics, University of Łódź, 12/16 Banacha St., Łódź 90-237, Poland.
Klajnert
B
B
Bryszewska
M
M
D000327:Adsorption; D001672:Biocompatible Materials / Q000737:chemistry*; D004161:Diphenylhexatriene / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D046911:Macromolecular Substances; D008968:Molecular Conformation; D011073:Polyamines / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry; D013050:Spectrometry, Fluorescence / Q000379:methods*; D013229:Stearic Acids / Q000032:analysis / Q000737:chemistry*
D001672:Biocompatible Materials; D005456:Fluorescent Dyes; D046911:Macromolecular Substances; D011073:Polyamines; D011108:Polymers; D013229:Stearic Acids; C026653:12-(9-anthroyloxy)stearic acid; D004161:Diphenylhexatriene; C033628:1-(4-(trimethylamino)phenyl)-6-phenylhexa-1,3,5-triene