Anti-inflammatory and antinociceptive activities of Lippia nodiflora Linn.
The methanolic extract of leaves of Lippia nodiflora Linn. was tested for its anti-inflammatory and antinociceptive activities. The extract showed a significant (P < 0.001) anti-inflammatory activity comparable to phenylbutazone against carrageenin-induced paw edema in rats and a significant (P < 0.001) antinociceptive activity comparable to diclofenac sodium in acetic acid induced writhing in white albino mice.
Ahmed
F
F
Pharmacy Discipline, Khulna University, Khulna, Bangladesh. firoj72@yahoo.com
Selim
M S T
MS
Das
A K
AK
Choudhuri
M S K
MS
D019342:Acetic Acid; D000700:Analgesics / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000302:isolation & purification / Q000494:pharmacology*; D002351:Carrageenan; D004008:Diclofenac / Q000627:therapeutic use; D004487:Edema / Q000139:chemically induced / Q000473:pathology / Q000517:prevention & control; D005260:Female; D005528:Foot / Q000473:pathology; D032411:Lippia / Q000737:chemistry*; D008297:Male; D051379:Mice; D010147:Pain Measurement / Q000187:drug effects; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D051381:Rats
D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D010936:Plant Extracts; D004008:Diclofenac; D002351:Carrageenan; D019342:Acetic Acid