title: Assessing respiratory drive and central motor pathway in humans: clinical implications.
abstract: Feedback from sensory elements as well as projection from higher Central Nervous System structures modify the level and pattern of motor outflow to the respiratory muscles and hence ventilation. In this review we describe the different methods to evaluate the degree to which higher centers determine the level and pattern of ventilation and coordinate use of the respiratory muscles in healthy humans and in patients with a number of respiratory disorders.
authors.affiliation: Don C. Gnocchi Foundation (IRCCS), Section of Respiratory Rehabilitation, Pozzolatico, Florence, Italy.
authors.forename: B
authors.initials: B
authors.lastname: Binazzi
authors.forename: B
authors.initials: B
authors.lastname: Lanini
authors.forename: G
authors.initials: G
authors.lastname: Scano
mesh_terms: D003964:Diaphragm / Q000502:physiology; D004525:Efferent Pathways / Q000502:physiology; D004576:Electromyography; D005246:Feedback / Q000502:physiology*; D006801:Humans; D011999:Recruitment, Neurophysiological; D012119:Respiration; D012132:Respiratory Muscles / Q000502:physiology*; D014109:Total Lung Capacity