Eye nutrient products for age-related macular degeneration: what do they contain?
OBJECTIVE
Patients are increasingly well informed about the availability of antioxidant products and the claims made for their benefits in age-related macular degeneration (AMD). Consequently, their use is becoming widespread. The purpose of this study is to conduct a survey of the commonly encountered products, and to compare their ingredients with the current Age-Related Eye Disease Study (AREDS) recommendations.


METHODS
A search was undertaken for products sold as 'eye nutrients' at local pharmacies and health food shops, and for products advertised via the Internet. Information about these products was collated and analysed.


RESULTS
We identified 22 eye nutrient products. Analysis of their constituents showed that, although over 75% contained all the constituents used in AREDS, only two matched the dosage profiles recommended in the study.


CONCLUSIONS
The authors draw no conclusion on the efficacy of nutritional supplements in the prevention of AMD. In order to advise their patients, ophthalmologists should be familiar with these products. The compiled list in this paper should provide a useful reference for them.
Arora
S
S
Wolverhampton and Midlands Counties Eye Infirmary, Wolverhampton, Midlands, UK. seema20@msn.com
Musadiq
M
M
Mukherji
S
S
Yang
Y C
YC
D000975:Antioxidants / Q000008:administration & dosage* / Q000737:chemistry / Q000600:supply & distribution; D001205:Ascorbic Acid / Q000008:administration & dosage; D003300:Copper / Q000008:administration & dosage; D019587:Dietary Supplements / Q000032:analysis; D006801:Humans; D008268:Macular Degeneration / Q000178:diet therapy / Q000517:prevention & control*; D014810:Vitamin E / Q000008:administration & dosage; D015032:Zinc / Q000008:administration & dosage; D019207:beta Carotene / Q000008:administration & dosage
D000975:Antioxidants; D019207:beta Carotene; D014810:Vitamin E; D003300:Copper; D015032:Zinc; D001205:Ascorbic Acid