Prognostic factors in 61 cases of Staphylococcus aureus prosthetic valve infective endocarditis from the International Collaboration on Endocarditis merged database.
Staphylococcus aureus prosthetic valve infective endocarditis (SA-PVIE) is associated with a high mortality rate, but prognostic factors have not been clearly elucidated. The International Collaboration on Endocarditis merged database (ICE-MD) contained 2212 cases of definite infective endocarditis (as defined using the Duke criteria), 61 of which were SA-PVIE. Overall mortality rate was 47.5%, stroke was associated with an increased risk of death, and early valve replacement was not associated with a significant survival benefit in the whole population; however, patients who developed cardiac complications and underwent early valve replacement had the lowest mortality rate (28.6%).
Chirouze
C
C
University Hospital of Besançon, France.
Cabell
C H
CH
Fowler
V G
VG
Khayat
N
N
Olaison
L
L
Miro
J M
JM
Habib
G
G
Abrutyn
E
E
Eykyn
S
S
Corey
G R
GR
Selton-Suty
C
C
Hoen
B
B
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016208:Databases, Factual; D004697:Endocarditis, Bacterial / Q000175:diagnosis* / Q000401:mortality; D005260:Female; D006349:Heart Valve Diseases / Q000601:surgery; D006350:Heart Valve Prosthesis / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016459:Prosthesis-Related Infections / Q000175:diagnosis* / Q000401:mortality; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000401:mortality; D013211:Staphylococcus aureus; D016019:Survival Analysis