title: Identification of a new allele, HLA-DRB1*1360, on a DRB5 haplotype in a Brazilian individual.
abstract: The application of DNA-based methods for human leukocyte antigen (HLA) genotyping has revealed an ever-increasing degree of polymorphism within the HLA-DRB loci and has resulted in the discovery of new alleles. We have identified a new DRB1 allele that was subsequently named DRB1*1360 by the WHO Nomenclature Committee. This allele is unusual for a DRB1*13 allele, as it is present on a DRB5 haplotype rather than the normal DRB3 haplotype found in association with DRB1*13 alleles.
authors.affiliation: Laboratory of Histocompatibility, Hemotherapy Center, University of Campinas, Campinas, Brazil. gvt@obelix.unicamp.br
authors.forename: G V
authors.initials: GV
authors.lastname: Testa
authors.forename: M
authors.initials: M
authors.lastname: Bunce
authors.forename: M H
authors.initials: MH
authors.lastname: Sheldon
authors.forename: P P J
authors.initials: PP
authors.lastname: Dunn
authors.forename: S
authors.initials: S
authors.lastname: Day
authors.forename: S B D
authors.initials: SB
authors.lastname: Marques
mesh_terms: D001483:Base Sequence; D001938:Brazil; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D059847:HLA-DRB5 Chains; D006239:Haplotypes; D006801:Humans; D008969:Molecular Sequence Data; D017385:Sequence Homology
chemical_list: D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; C495084:HLA-DRB1*13:60 antigen; D059847:HLA-DRB5 Chains