The relation between latent inhibition and symptom-types in young schizophrenics.
Latent inhibition (LI), retarded conditioning to a stimulus that has been previously repeatedly presented without reinforcement, was examined in young schizophrenics and normal controls using a within-subject visual search task. Healthy controls exhibited the usual LI effect. LI was potentiated in schizophrenics who simultaneously exhibited high levels of negative symptoms and low levels of positive symptoms. Schizophrenic groups with other combinations of positive and negative symptoms did not differ from controls. The pattern of data suggests that past inconsistencies in the LI-schizophrenia literature may be the result of opposing processes that are associated with positive and negative symptoms.
Cohen
Efrat
E
Department of Psychology, Tel Aviv University, Ramat Aviv 69978, Israel.
Sereni
Noam
N
Kaplan
O
O
Weizman
A
A
Kikinzon
L
L
Weiner
I
I
Lubow
R E
RE
D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007266:Inhibition, Psychological; D008297:Male; D011569:Psychiatric Status Rating Scales; D011930:Reaction Time / Q000502:physiology; D012559:Schizophrenia / Q000503:physiopathology*; D012565:Schizophrenic Psychology; D013647:Task Performance and Analysis; D014796:Visual Perception / Q000502:physiology*