title: Human frequency-following response correlates of the distortion product at 2F1-F2.
abstract: We characterized the 2F1-F2 distortion product reflected in the human frequency-following response (FFR). In the first experiment, we evaluated the input-output growth functions of the distortion product at 2F1-F2 (FFR-DP) for three primary pairs. In the second experiment, we tested the effect of primary tone level variation on the FFR-DP. The results for all three stimulus pairs showed that while the amplitude of FFR-DP increased with stimulus intensity, the slope of the amplitude growth decreased with increasing frequency. Consistent with distortion product otoacoustic emission (DPOAE) data, our observations suggest that there is a distinct region where the separation of the primary tone levels produces maximal distortion. The robust FFR-DP measure could complement the less reliable DPOAE at low frequencies and when middle ear pathology precludes its measurement.
authors.affiliation: School of Behavioral and Brain Sciences, GR 41, University of Texas at Dallas, Richardson, Texas 75083-0688, USA. pritesh@utdallas.edu
authors.forename: Pritesh K
authors.initials: PK
authors.lastname: Pandya
authors.forename: Ananthanarayan
authors.initials: A
authors.lastname: Krishnan
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001300:Audiometry, Evoked Response; D001933:Brain Stem / Q000502:physiology; D003056:Cochlear Nerve / Q000502:physiology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005583:Fourier Analysis; D006801:Humans; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*