Aging biology and cancer.
Epidemiologic analyses of current registries indicate that the majority of patients in the United States with cancer are 65 years old or older. Basic research in both gerontology and oncology has led to an understanding that these processes (normal aging and the development of cancer) have much in common. In this review we attempt to frame specific aspects of cancer biology in the context of normal aging.
Denduluri
Neelima
N
Institute for Advanced Studies in Aging & Geriatric Medicine, 1700 Wisconsin Avenue NW, Washington, DC 20007, USA.
Ershler
William B
WB
D000368:Aged; D000375:Aging / Q000235:genetics / Q000276:immunology / Q000502:physiology*; D000818:Animals; D002471:Cell Transformation, Neoplastic; D006801:Humans; D008017:Life Expectancy; D009369:Neoplasms / Q000453:epidemiology* / Q000503:physiopathology