title: Adjunctive benefit of an essential oil-containing mouthrinse in reducing plaque and gingivitis in patients who brush and floss regularly: a six-month study.
abstract: BACKGROUND
  Mechanical methods of oral hygiene can be complemented by the use of chemotherapeutic mouthrinses. The authors sought to quantify the additional benefit provided by an essential oil-, or EO-, containing mouthrinse in reducing plaque and gingivitis in patients who brush and floss regularly.
  
  
  METHODS
  The authors randomly assigned patients with gingivitis to one of three treatment groups: brushing and rinsing with a control mouthrinse, or BC; brushing, flossing and rinsing with a control mouthrinse, or BFC; or brushing, flossing and rinsing with an EO-containing mouthrinse, or BFEO. Patients received a dental prophylaxis at baseline, and the authors followed them for six months.
  
  
  RESULTS
  Of 246 enrolled subjects enrolled in the study, 237 subjects were evaluable at the study's conclusion. After six months, the subjects using the BFEO regimen had statistically and clinically significant lower mean Modified Gingival Index, or MGI, scores and Plaque Index, or PI, scores than did subjects in the BC group (29.9 percent and 56.3 percent, respectively; P < .001). Subjects in the BFC group had statistically significantly lower mean MGI and PI scores than did subjects in the BC group (11.2 percent and 9.3 percent, respectively; P < .001). Subjects in the BFEO group exhibited statistically and clinically significantly lower mean scores for MGI and PI than did subjects in the BFC group (21 percent and 51.9 percent, respectively; P < .001).
  
  
  CONCLUSIONS
  This study confirms that for patients with gingivitis who brush and floss routinely, the adjunctive use of an EO-containing mouthrinse provides a clinically significant and meaningful additional benefit in reducing plaque and gingivitis.
  
  
  CONCLUSIONS
  An EO-containing mouthrinse is an effective adjunct to regular brushing and flossing. Therefore, the BFEO regimen can be beneficial for patients with gingival inflammation.
authors.affiliation: BioSci Research Canada, Mississauga, Ontario.
authors.forename: N
authors.initials: N
authors.lastname: Sharma
authors.forename: C H
authors.initials: CH
authors.lastname: Charles
authors.forename: M C
authors.initials: MC
authors.lastname: Lynch
authors.forename: J
authors.initials: J
authors.lastname: Qaqish
authors.forename: J A
authors.initials: JA
authors.lastname: McGuire
authors.forename: J G
authors.initials: JG
authors.lastname: Galustians
authors.forename: L D
authors.initials: LD
authors.lastname: Kumar
mesh_terms: D000293:Adolescent; D000328:Adult; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D016009:Chi-Square Distribution; D003742:Dental Devices, Home Care; D003773:Dental Plaque / Q000517:prevention & control*; D003774:Dental Plaque Index; D003802:Dentifrices / Q000627:therapeutic use; D004338:Drug Combinations; D005260:Female; D005500:Follow-Up Studies; D005884:Gingival Hemorrhage / Q000517:prevention & control; D005891:Gingivitis / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes / Q000627:therapeutic use*; D009822:Oils, Volatile / Q000627:therapeutic use*; D010512:Periodontal Index; D012459:Salicylates / Q000627:therapeutic use; D016037:Single-Blind Method; D013729:Terpenes / Q000627:therapeutic use; D014099:Toothbrushing
chemical_list: D000891:Anti-Infective Agents, Local; D003802:Dentifrices; D004338:Drug Combinations; D009067:Mouthwashes; D009822:Oils, Volatile; D012459:Salicylates; D013729:Terpenes; C057473:Listerine