title: Albusin B, a bacteriocin from the ruminal bacterium Ruminococcus albus 7 that inhibits growth of Ruminococcus flavefaciens.
abstract: An approximately 32-kDa protein (albusin B) that inhibited growth of Ruminococcus flavefaciens FD-1 was isolated from culture supernatants of Ruminococcus albus 7. Traditional cloning and gene-walking PCR techniques revealed an open reading frame (albB) encoding a protein with a predicted molecular mass of 32,168 Da. A BLAST search revealed two homologs of AlbB from the unfinished genome of R. albus 8 and moderate similarity to LlpA, a recently described 30-kDa bacteriocin from Pseudomonas sp. strain BW11M1.
authors.affiliation: Department of Bacteriology, University of Wisconsin-Madison, USA.
authors.forename: Junqin
authors.initials: J
authors.lastname: Chen
authors.forename: David M
authors.initials: DM
authors.lastname: Stevenson
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Weimer
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001430:Bacteriocins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism* / Q000494:pharmacology*; D017077:Culture Media, Conditioned; D008969:Molecular Sequence Data; D012417:Rumen / Q000382:microbiology*; D045857:Ruminococcus / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA
chemical_list: D001430:Bacteriocins; D017077:Culture Media, Conditioned