title: Evaluating the responsiveness of the Endometriosis Health Profile Questionnaire: the EHP-30.
abstract: OBJECTIVE
  To evaluate the sensitivity to change of the Endometriosis Health Profile-30 (EHP-30) questionnaire.
  
  
  METHODS
  The Women's Center, John Radcliffe Hospital, Oxford.
  
  
  METHODS
  Postal survey to 66 women undergoing conservative surgery for the treatment of endometriosis-associated pain. The EHP-30 and the Short Form-36 (SF-36) were administered 2 weeks before the operation, and 4 months post-operatively. At T2 a transition question was included to evaluate changes in patients health status. To evaluate responsiveness effect sizes, standardised response means, the index of responsiveness and the minimally and clinically important differences were calculated.
  
  
  RESULTS
  Forty (66.6%) patients returned the questionnaires at time 1 and 2. Overall less responsive effect size scores were found for the SF-36 (0.1-0.5) compared to the EHP-30 (-0.1-1.1) for all patients who had undergone treatment. Minimally important differences and the index of responsiveness were overall higher for the EHP-30 (0.4-2.0) compared to the SF-36 (0.1-1.0). Change scores for four of the five scales were significantly correlated with women's responses to the transition question.
  
  
  CONCLUSIONS
  Results suggest that the EHP-30 is sensitive to change. Its application in clinical trials should prove beneficial in assessing the impact of medical and surgical interventions upon quality of life for women with endometriosis.
authors.affiliation: Nuffield Department of Obstetrics and Gynaecology, University of Oxford, United Kingdom. g.l.jones@sheffield.ac.uk
authors.forename: Georgina
authors.initials: G
authors.lastname: Jones
authors.forename: Crispin
authors.initials: C
authors.lastname: Jenkinson
authors.forename: Stephen
authors.initials: S
authors.lastname: Kennedy
mesh_terms: D000328:Adult; D004715:Endometriosis / Q000503:physiopathology / Q000523:psychology* / Q000601:surgery*; D004739:England; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D010147:Pain Measurement / Q000523:psychology; D011594:Psychometrics / Q000295:instrumentation*; D011788:Quality of Life; D012680:Sensitivity and Specificity; D018434:Sickness Impact Profile; D012944:Social Support; D011795:Surveys and Questionnaires / Q000592:standards*; D013997:Time Factors; D016896:Treatment Outcome