title: Acute paraplegia associated with vasculitis in a dog with leishmaniasis.
abstract: A 14-month-old female crossbreed dog with leishmaniasis, receiving allopurinol, was presented with acute paraplegia. A diagnosis of renal failure with pelvic limb lower motor neuron signs was made and the dog was euthanased. Histopathological examination demonstrated leukocytoclastic vasculitis in multiple organs. Malacia and haemorrhage affecting the spinal cord was associated with multiple foci of vasculitis within the nervous tissue. Rupture and thrombosis of inflamed vessels caused haemorrhage in the spinal cord and subsequent paralysis.
authors.affiliation: Hospital Ars Veterinaria, Carrer Cardedeu 3, 08023 Barcelona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Font
authors.forename: J
authors.initials: J
authors.lastname: Mascort
authors.forename: J
authors.initials: J
authors.lastname: Altimira
authors.forename: J M
authors.initials: JM
authors.lastname: Closa
authors.forename: M
authors.initials: M
authors.lastname: Vilafranca
mesh_terms: D000208:Acute Disease; D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D005260:Female; D007896:Leishmaniasis / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D010264:Paraplegia / Q000209:etiology / Q000662:veterinary; D013118:Spinal Cord Diseases / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D014657:Vasculitis / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*