Unusual transcription regulation of the niaD gene under anaerobic conditions supporting fungal ammonia fermentation.
The niaD gene of the fungus Aspergillus nidulans encodes an assimilatory nitrate reductase and exogenous ammonium represses its expression. Under anoxic conditions, however, A. nidulans expressed niaD even in the presence of ammonium and used the gene product for dissimilatory nitrate reduction (ammonia fermentation). This transcription regulation mechanism under anaerobiosis is critical for the fungus to ferment ammonium.
Takasaki
Kazuto
K
Institute of Applied Biochemistry, University of Tsukuba, Ibaraki, Japan.
Shoun
Hirofumi
H
Nakamura
Akira
A
Hoshino
Takayuki
T
Takaya
Naoki
N
D000641:Ammonia / Q000378:metabolism*; D000693:Anaerobiosis / Q000187:drug effects; D001233:Aspergillus nidulans / Q000235:genetics* / Q000378:metabolism*; D002457:Cell Extracts; D005285:Fermentation / Q000187:drug effects; D005656:Fungal Proteins / Q000235:genetics; D015966:Gene Expression Regulation, Fungal / Q000187:drug effects; D005800:Genes, Fungal / Q000235:genetics*; D009566:Nitrates / Q000494:pharmacology; D009572:Nitrite Reductases / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism / Q000494:pharmacology; D014158:Transcription, Genetic / Q000187:drug effects / Q000235:genetics*; D001617:beta-Glucosidase / Q000378:metabolism
D002457:Cell Extracts; D005656:Fungal Proteins; D009566:Nitrates; D000641:Ammonia; D009572:Nitrite Reductases; D001617:beta-Glucosidase; D010100:Oxygen