Fractal branching pattern of the monopodial canine airway.
Unlike the human lung, monopodial canine airway branching follows an irregular dichotomized pattern with fractal features. We studied three canine airway molds and found a self-similarity feature from macro- to microscopic scales, which formed a fractal set up to seven scales in the airways. At each fractal scale, lateral branches evenly lined up along an approximately straight main trunk to form three to four two-dimensional structures, and each lateral branch was the monopodial main trunk of the next fractal scale. We defined this pattern as the fractal main lateral-branching pattern, which exhibited similar structures from macro- to microscopic scales, including lobes, sublobes, sub-sublobes, etc. We speculate that it, rather than a mother-daughter pattern, could better describe the actual asymmetrical architecture of the monopodial canine airway.
Wang
Ping M
PM
School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA. ping.wang@che.gatech.edu
Kraman
Steve S
SS
D000818:Animals; D004285:Dogs / Q000033:anatomy & histology*; D017709:Fractals; D008168:Lung / Q000033:anatomy & histology*; D008953:Models, Anatomic; D012137:Respiratory System / Q000033:anatomy & histology*; D012828:Silicones
D012828:Silicones