Vanilloid receptor TRPV1 antagonists as the next generation of painkillers. Are we putting the cart before the horse?
Szallasi
Arpad
A
Department of Pathology and Laboratory Medicine, 6 Founders Building, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, Pennsylvania 19104, USA. szallasa@uphs.upenn.edu
Appendino
Giovanni
G
D000700:Analgesics / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D002211:Capsaicin / Q000378:metabolism*; D015195:Drug Design; D006801:Humans; D011955:Receptors, Drug / Q000037:antagonists & inhibitors*
D000700:Analgesics; D011955:Receptors, Drug; D002211:Capsaicin