title: Human fascioliasis.
abstract: Fasciola hepatica, a zoonotic liver fluke, can also cause disease in humans. Common symptoms are epigastric pain, upper abdominal pain and malaise. Fever and arthralgia are common in acute fascioliasis. Eosinophilia is the predominant laboratory finding, especially in patients with the acute form of the disease. Diagnosis and treatment is not easy, as physicians rarely encounter this disease, and effective drugs are not available in many countries. Human fascioliasis may be underestimated. Patients with eosinophilia and abdominal pain should be evaluated for F. hepatica infestation by parasitological, radiological and serological tests.
authors.affiliation: Akdeniz University, Infectious Diseases and Clinical Microbiology, Antalya, Turkey. rabin@akdeniz.edu.tr
authors.forename: R
authors.initials: R
authors.lastname: Saba
authors.forename: M
authors.initials: M
authors.lastname: Korkmaz
authors.forename: D
authors.initials: D
authors.lastname: Inan
authors.forename: L
authors.initials: L
authors.lastname: Mamikoğlu
authors.forename: O
authors.initials: O
authors.lastname: Turhan
authors.forename: F
authors.initials: F
authors.lastname: Günseren
authors.forename: C
authors.initials: C
authors.lastname: Cevikol
authors.forename: A
authors.initials: A
authors.lastname: Kabaalioğlu
mesh_terms: D000328:Adult; D000368:Aged; D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000909:Antibodies, Helminth / Q000032:analysis; D000980:Antiplatyhelmintic Agents / Q000627:therapeutic use; D001562:Benzimidazoles / Q000627:therapeutic use; D005210:Fasciola hepatica / Q000187:drug effects / Q000276:immunology; D005211:Fascioliasis / Q000175:diagnosis* / Q000188:drug therapy* / Q000469:parasitology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011223:Praziquantel / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000077682:Triclabendazole
chemical_list: D000909:Antibodies, Helminth; D000980:Antiplatyhelmintic Agents; D001562:Benzimidazoles; D000077682:Triclabendazole; C084442:praziquanamine; D011223:Praziquantel; D015766:Albendazole