title: Oedematous skin disease of buffalo in Egypt.
abstract: This review covers a historical view and etiology of oedematous skin disease which affects buffalo in Egypt, the microbiology of Corynebacterium pseudotuberculosis causing the disease: its virulence; clinical signs; mechanism of pathogenesis; histopathology; mode of transmission; immunological aspects; treatment and control. It is concluded that C. pseudotuberculosis serotype II is the main cause of OSD and exotoxin phospholipase D and its lipid contents of the cell wall are the major causes of pathogenesis. After declaring the role of Hippobosca equina in transmission of the causative agent among buffaloes, control of OSD is now available.
authors.affiliation: Center for Biotechnology Services and Researches, Veterinary Faculty, Cairo University, Giza, Egypt.
authors.forename: S A
authors.initials: SA
authors.lastname: Selim
mesh_terms: D000818:Animals; D002020:Buffaloes; D002473:Cell Wall; D003354:Corynebacterium Infections / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D016925:Corynebacterium pseudotuberculosis / Q000378:metabolism / Q000472:pathogenicity*; D004487:Edema / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology / Q000662:veterinary; D004534:Egypt / Q000453:epidemiology; D005098:Exotoxins / Q000096:biosynthesis*; D008055:Lipids / Q000032:analysis*; D010739:Phospholipase D / Q000032:analysis; D017192:Skin Diseases, Bacterial / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D014774:Virulence
chemical_list: D005098:Exotoxins; D008055:Lipids; D010739:Phospholipase D