[Analysis of postoperative recurrence of malignant tumors of adrenal glands].
Malignant tumors of suprarenal glands (MTSG) are characterized by aggressive course, inclination to recurrences and early metastatic spreading. Causes of the recurrence occurrence of MTSG were analyzed in 292 patients. There was revealed more frequent recurrence of tumor of the adrenal gland cortical substance than of medullary substance. In anaplastic and low differentiated forms of cancer the prognosis is poor, efficacy of treatment is extremely low. Most frequently (in 63.5% of observations) the recurrence is localized in regional collectors of the lymph outflow. Elaboration of operative interventions, which include prophylactic systemic dissection of retroperitoneal fat, would have to permit to lower the recurrence frequency after primary surgical intervention. Occurrence of the tumor recurrence after primary operation constitute a bad prognostic sign. Of the patients with the tumor recurrence 55.8% are considered incurable.
Kvacheniuk
A N
AN
D000310:Adrenal Gland Neoplasms / Q000188:drug therapy / Q000601:surgery*; D000315:Adrenalectomy / Q000379:methods; D000328:Adult; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008939:Mitotane / Q000627:therapeutic use; D009364:Neoplasm Recurrence, Local; D011184:Postoperative Period
D018931:Antineoplastic Agents, Hormonal; D008939:Mitotane