Meningoradiculitis due to Cryptococcus neofermans in an immunocompetent patient.
Meningoradiculitis refers to combined involvement of meninges and nerve roots. The most frequent location is the lumbosacral region. Etiology is diverse, including inflammatory, infectious and neoplastic disorders. Meningoradiculitis is a rare form of involvement in cryptococcal infection. We describe a case of subacute lower limbs flaccid paresis diagnosed as lumbosacral meningoradiculitis in view of cerebrospinal fluid (CSF) inflammatory changes and typical enhancement on MRI of lumbar spine. Cryptococcus neoformans was isolated from CSF. Extensive screening yielded no immunodeficiencies.
Deus-Silva
Leonardo
L
Department of Neurology, Medical Sciences School, Campinas State University, Sp, Brazil. dedeus@unicamp.br
Costa
Alexandre E
AE
Bevilacqua
Juliano M
JM
Assis
Denise B
DB
Ferraz
Carlos A
CA
Oliveira
Augusto C P
AC
Nucci
Anamarli
A
D000293:Adolescent; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D003453:Cryptococcosis / Q000188:drug therapy; D003455:Cryptococcus neoformans / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D007121:Immunocompetence; D008161:Lumbosacral Region; D008279:Magnetic Resonance Imaging; D016919:Meningitis, Cryptococcal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D011843:Radiculopathy / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*
D000935:Antifungal Agents; D000666:Amphotericin B