The SDF-1/CXCL 12/CXCR4 biological axis in non-small cell lung cancer metastases.
Belperio
John A
JA
Department of Medicine and Pathology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024-1922, USA. jbelperio@mednet.org
Phillips
Roderick J
RJ
Burdick
Marie D
MD
Lutz
Marin
M
Keane
Michael
M
Strieter
Robert
R
D000818:Animals; D002289:Carcinoma, Non-Small-Cell Lung / Q000556:secondary*; D054377:Chemokine CXCL12; D019743:Chemokines, CXC / Q000378:metabolism*; D002633:Chemotaxis; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D051379:Mice; D016513:Mice, SCID; D009363:Neoplasm Proteins / Q000378:metabolism*; D054398:Receptors, CCR4; D019707:Receptors, Chemokine / Q000378:metabolism*
C515354:CCR4 protein, human; C515255:CXCL12 protein, human; C515355:Ccr4 protein, mouse; D054377:Chemokine CXCL12; D019743:Chemokines, CXC; C515256:Cxcl12 protein, mouse; D009363:Neoplasm Proteins; D054398:Receptors, CCR4; D019707:Receptors, Chemokine