[Outcome and efficacy of laparoscopic splenectomy in treatment of idiopathic thrombocytopenic purpura].
OBJECTIVE
To investigate the safety and efficacy of laparoscopic splenectomy (LS) in treatment of idiopathic thrombocytopenic purpura (ITP).


METHODS
Twenty-one patients with ITP underwent LS. The data of preoperative and postoperative platelet counts, intraoperative blood loss, recovery time, hospital stay time, and complications were analyzed prospectively.


RESULTS
The platelet count was elevated rapidly in one week, and peristalsis of alimentary tract was recovered in 24 hours after operation in all cases. All patients got out of bed within 6 hours postoperatively. Their mean hospitalization time was 4 days. Complications were seen in 4 cases, of which one case underwent laparotomy, one case underwent laparoscopy once more to stop bleeding, one case developed subdiaphragmatic infection, and one case developed subcutaneous emphysema. Sixteen patients were followed up, and 2 patients relapsed.


CONCLUSIONS
LS is a relatively safe and effective measure for treatment of ITP.
Wang
Xian-fa
XF
Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, China.
Cai
Xiu-jun
XJ
Li
Wei
W
Yu
Hong
H
Liang
Xiao
X
Cai
Xiao-yan
XY
D000293:Adolescent; D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000378:metabolism; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007430:Intraoperative Care; D010535:Laparoscopy; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011183:Postoperative Complications; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000601:surgery*; D012189:Retrospective Studies; D013156:Splenectomy / Q000379:methods*; D016896:Treatment Outcome