title: Benign fibrous histiocytoma of prepuce in the mule.
abstract: Here we present a case of preputial benign fibrous histiocytoma in a 7-year-old mule. This case was treated surgically. Pathologic analysis and diagnosis of these lesions were based on a combination of light microscopy and immunohistochemistry. Histologically, the tumour was composed primarily of a storiform pattern of fibroblastic and poligonal cells. In immunohistochemistry, except for consistent immunoreactivity for vimentin, nearly all tumour cells were positive for CD68, S-100 protein, pan-cytokeratin, alpha-smooth muscle actin, and desmin. Benign fibrous histiocytoma of the prepuce in mule is rarely reported in veterinary literature.
authors.affiliation: Dipartimento di Sanità Pubblica Veterinaria, Sezione di Patologia Generale e Anatomia Patologica, Facoltà di Medicina Veterinaria, Università degli Studi di Messina, Messina, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Rapisarda
authors.forename: F
authors.initials: F
authors.lastname: Marino
authors.forename: G
authors.initials: G
authors.lastname: Ferrara
authors.forename: F
authors.initials: F
authors.lastname: Gioffrè
authors.forename: V
authors.initials: V
authors.lastname: Galofaro
mesh_terms: D000818:Animals; D003937:Diagnosis, Differential; D018397:Equidae; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis / Q000662:veterinary*; D006734:Horse Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006736:Horses; D007150:Immunohistochemistry / Q000662:veterinary; D008297:Male; D010412:Penile Neoplasms / Q000175:diagnosis / Q000662:veterinary*