title: Recurrent aphthous ulcers in Fanconi's anaemia: a case report.
abstract: Fanconi's anaemia (FA) is an autosomal recessive disorder that is clinically characterized by aplastic anaemia, congenital malformations of the renal, cardiac, skeletal and skin structures, and an increased predisposition to malignancies. Patients with FA often present with bleeding and infection, which are symptoms related to thrombocytopenia and neutropenia. There are few reports of the oral manifestations of FA. We describe oral aphthous ulcerations in two siblings with FA. There was a rapid improvement and healing of ulcers after blood transfusions and increased haemoglobin levels. This may support the role of severe anaemia in oral ulcerations.
authors.affiliation: Ondokuz Mayis University, Faculty of Dentistry, Department of Periodontology, Kurupelit-Samsun, Turkey.
authors.forename: Feyza
authors.initials: F
authors.lastname: Otan
authors.forename: Gokhan
authors.initials: G
authors.lastname: Açikgöz
authors.forename: Umur
authors.initials: U
authors.lastname: Sakallioglu
authors.forename: Burcu
authors.initials: B
authors.lastname: Ozkan
mesh_terms: D000293:Adolescent; D001803:Blood Transfusion; D002648:Child; D005199:Fanconi Anemia / Q000150:complications* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D012008:Recurrence; D013281:Stomatitis, Aphthous / Q000209:etiology*