title: Carcinoma arising in the pleural cavity following pneumonectomy for hydatid disease.
abstract: We report a case of carcinoma following 42 years of chronic empyema in a patient who underwent surgery for a hydatid cyst at the age of 3. At the time of diagnosis, an esophageal fistula was observed and treated with cyanoacrylate. We hypothesize that chronic inflammation of the pleura, caused by decades of empyema, associated with the presence of heterotopic squamous epithelium due to a long-standing esophago-pleural fistula, led to neoplastic transformation.
authors.affiliation: Department of Thoracic Surgery, Fundación Jiménez Díaz, Hospital Ramón y Cajal, Madrid, Spain. zapatero89@hotmail.com
authors.forename: J
authors.initials: J
authors.lastname: Zapatero Gaviria
authors.forename: C E
authors.initials: CE
authors.lastname: Garcia Franco
authors.forename: L
authors.initials: L
authors.lastname: Jimenez Hiscock
authors.forename: R
authors.initials: R
authors.lastname: Peñalver Pascual
authors.forename: L
authors.initials: L
authors.lastname: Fogué Calv O
authors.forename: I
authors.initials: I
authors.lastname: Muguruza Trueba
authors.forename: J
authors.initials: J
authors.lastname: Lago Viguera
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D002908:Chronic Disease; D003487:Cyanoacrylates / Q000627:therapeutic use; D004445:Echinococcosis, Pulmonary / Q000150:complications* / Q000601:surgery; D004653:Empyema / Q000209:etiology* / Q000601:surgery; D004937:Esophageal Fistula / Q000188:drug therapy / Q000209:etiology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000209:etiology*; D011013:Pneumonectomy / Q000009:adverse effects; D012086:Reoperation; D013997:Time Factors; D014014:Tissue Adhesives / Q000627:therapeutic use
chemical_list: D003487:Cyanoacrylates; D014014:Tissue Adhesives