title: Cardiopulmonary exercise testing before and one year after mitral valve repair for severe mitral regurgitation.
abstract: For the evaluation of efficacy of cardiopulmonary exercise testing, we compared New York Heart Association functional class with peak oxygen consumption rate (VO(2)peak) in 31 patients with severe mitral regurgitation who underwent mitral valve repair surgery. One year later, the VO(2)peak values did not show significant improvement; however, the patients who had more than a mild degree of residual mitral regurgitation (n = 14) after 1 year of surgery had a VO(2)peak value that was significantly decreased (from 22.7 +/- 6.4 to 21.0 +/- 6.3 ml/kg/min, p = 0.04). Patients with a higher preoperative VO(2)peak value (>/=18.5 ml/kg/min) had a significantly better New York Heart Association functional class 1 year after surgery than patients with a lower VO(2)peak value (<18.5 ml/kg/min, p = 0.03).
authors.affiliation: Division of Cardiovascular Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
authors.forename: Hyun-Joong
authors.initials: HJ
authors.lastname: Kim
authors.forename: Seok Jin
authors.initials: SJ
authors.lastname: Ahn
authors.forename: Seung Woo
authors.initials: SW
authors.lastname: Park
authors.forename: Byung Ryul
authors.initials: BR
authors.lastname: Cho
authors.forename: Jidong
authors.initials: J
authors.lastname: Sung
authors.forename: Sun-Hee
authors.initials: SH
authors.lastname: Hong
authors.forename: Pyo Won
authors.initials: PW
authors.lastname: Park
authors.forename: Kyung Pyo
authors.initials: KP
authors.lastname: Hong
mesh_terms: D000328:Adult; D004452:Echocardiography; D005080:Exercise Test; D017079:Exercise Tolerance / Q000502:physiology; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000503:physiopathology / Q000601:surgery*; D010101:Oxygen Consumption / Q000502:physiology; D010807:Physical Endurance / Q000502:physiology; D011182:Postoperative Care; D011300:Preoperative Care; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome; D016277:Ventricular Function, Left / Q000502:physiology