Applied biocatalysis for the synthesis of natural flavour compounds--current industrial processes and future prospects.
The industrial application of biocatalysis for the production of natural flavour compounds is illustrated by a discussion of the production of vanillin, gamma-decalactone, carboxylic acids, C6 aldehydes and alcohols ('green notes'), esters, and 2-phenylethanol. Modern techniques of molecular biology and process engineering, such as heterologous expression of genes, site-directed mutagenesis, whole-cell biocatalysis in biphasic systems, and cofactor regeneration for in vitro oxygenation, may result in more biocatalytic processes for the production of flavour compounds in the future.
Schrader
J
J
Karl Winnacker Institute, DECHEMA e.V., Theodor-Heuss-Allee 25, 60486 Frankfurt/Main, Germany. schrader@dechema.de
Etschmann
M M W
MM
Sell
D
D
Hilmer
J M
JM
Rabenhorst
J
J
D001709:Biotechnology / Q000639:trends*; D002384:Catalysis; D004798:Enzymes / Q000235:genetics / Q000378:metabolism*; D005421:Flavoring Agents / Q000138:chemical synthesis*; D015870:Gene Expression / Q000235:genetics; D005818:Genetic Engineering / Q000379:methods; D016297:Mutagenesis, Site-Directed
D004798:Enzymes; D005421:Flavoring Agents