Topical prostaglandin F(2alpha) analog induced poliosis.
OBJECTIVE
To report poliosis as a side effect associated with topical prostaglandin F(2alpha) (PGF(2alpha)) analogs.


METHODS
Case series.


RESULTS
Seven patients treated with different topical PGF(2alpha) analogs for primary open angle glaucoma developed bilateral poliosis, either alone or in combination with other adverse effects of PGF(2alpha) analog therapy.


CONCLUSIONS
Poliosis is a possible adverse effect of topical PGF(2alpha) analog therapy which is previously unreported. Topical PGF(2alpha) analog therapy should be included in the differential diagnosis of patients with poliosis.
Chen
Celia S
CS
Department of Ophthalmology, Flinders Medical Centre, Bedford Drive, Bedford Park, Adelaide, SA 5042, Australia.
Wells
Jane
J
Craig
Jamie E
JE
D000287:Administration, Topical; D000368:Aged; D000369:Aged, 80 and over; D000577:Amides; D000959:Antihypertensive Agents / Q000009:adverse effects*; D000069580:Bimatoprost; D003008:Cloprostenol / Q000009:adverse effects* / Q000031:analogs & derivatives*; D005140:Eyelashes / Q000187:drug effects*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000188:drug therapy; D006201:Hair Diseases / Q000139:chemically induced*; D006801:Humans; D006983:Hypertrichosis / Q000139:chemically induced; D007429:Intraocular Pressure / Q000187:drug effects; D000077338:Latanoprost; D008055:Lipids / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010859:Pigmentation Disorders / Q000139:chemically induced*; D011461:Prostaglandins F, Synthetic / Q000009:adverse effects*; D000069557:Travoprost
D000577:Amides; D000959:Antihypertensive Agents; D008055:Lipids; D011461:Prostaglandins F, Synthetic; D003008:Cloprostenol; D000077338:Latanoprost; D000069580:Bimatoprost; D000069557:Travoprost