title: Management of primary breast cancer: an update.
abstract: Based on results of trials emerged during the last 2 years and on data presented at the 8th International Conference on Primary Therapy of Early Breast Cancer held in 2003 in St. Gallen, a summary of current knowledge and controversies in the management of breast cancer is given. The following topics are covered: screening, biology, surgery, radiation therapy, primary systemic therapy, and adjuvant therapy (biological therapies, chemotherapy, endocrine therapies including ovarian ablation, and their interactions).
authors.affiliation: Senologie-Zentrum Ostschweiz (SENZO), Kantonsspital, St. Gallen, Switzerland. beat.thuerlimann@kssg.ch
authors.forename: B
authors.initials: B
authors.lastname: Thürlimann
authors.forename: A
authors.initials: A
authors.lastname: Müller
authors.forename: H-J
authors.initials: HJ
authors.lastname: Senn
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy*; D017024:Chemotherapy, Adjuvant / Q000379:methods*; D004965:Estrogen Antagonists / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010346:Patient Care Management / Q000379:methods* / Q000639:trends*
chemical_list: D000970:Antineoplastic Agents; D018931:Antineoplastic Agents, Hormonal; D004965:Estrogen Antagonists