Recurrent eosinophilic cystitis in a child with chronic granulomatous disease.
Eosinophilic cystitis is an uncommon disease in children, and its association with chronic granulomatous disease (CGD) has been previously reported in only five patients. In all those patients the disease showed either a self-limited benign course or a rapid response to corticosteroid treatment. The authors describe a child with X-linked CGD who developed eosinophilic cystitis with a recurrent course and difficult therapeutic management. The authors also discuss the pathogenesis of granuloma formation in CGD and review the literature for current therapies for these complications.
Barese
Cecilia N
CN
Division of Immunology, Hospital de Niños "Dr. Ricardo Gutierrez", Associated Hospital to the Universidad de Buenos Aires, Argentina. cecilia.barese@datamarkets.com.ar
Podestá
Miguel
M
Litvak
Edith
E
Villa
Mariana
M
Rivas
Eva María
EM
D016572:Cyclosporine / Q000627:therapeutic use; D003556:Cystitis / Q000209:etiology*; D004802:Eosinophilia / Q000209:etiology*; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007223:Infant; D008297:Male; D008969:Molecular Sequence Data; D011241:Prednisone / Q000627:therapeutic use; D012008:Recurrence; D016896:Treatment Outcome; D014463:Ultrasonography; D001743:Urinary Bladder / Q000000981:diagnostic imaging
D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011241:Prednisone