Usefulness of the third heart sound in predicting an elevated level of B-type natriuretic peptide.
Third heart sounds were sought in 100 consecutive outpatients who had B-type natriuretic peptide (BNP) levels measured within 8 hours. Mean BNP levels were significantly higher in those with a third heart sound. The presence of a third heart sound was 41% sensitive and 97% specific for elevated BNP levels.
Marcus
Gregory M
GM
Department of Cardiology, University of California-San Francisco, M1180D, 505 Parnassus Avenue, San Francisco, CA 94143-0124, USA. marcusg@medicine.ucsf.edu
Michaels
Andrew D
AD
De Marco
Teresa
T
McCulloch
Charles E
CE
Chatterjee
Kanu
K
D000368:Aged; D001314:Auscultation / Q000379:methods*; D004311:Double-Blind Method; D005260:Female; D006331:Heart Diseases / Q000097:blood* / Q000175:diagnosis*; D006801:Humans; D008297:Male; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012680:Sensitivity and Specificity
D020097:Natriuretic Peptide, Brain