title: Assessment of medial olivocochlear system function in pre-term and full-term newborns using a rapid test of transient otoacoustic emissions.
abstract: This study was conducted to investigate maturation of the medial olivocochlear efferent system (MOCS) in pre- and full-term neonates using Quickscreen (Otodynamics Ltd) and to confirm previous findings on transient otoacoustic emission (TEOAE) suppression in neonates. MOCS maturation was investigated in 46 neonates born at the Chaim Sheba Medical Center, Tel Hashomer, Israel, using Quickscreen. All neonates were normal with no family history of general or auditory disease and no risk factors for hearing impairment. MOCS function appears gradually in human pre-term neonates and is considered to reach maturity shortly after term birth. The clinical value of MOCS testing in specific populations of newborns at risk for hearing and/or brainstem function can be legitimately raised as activation of the MOCS clearly alters cochlear output. The present results can be interpreted to support the testing of infants at risk of developing abnormal MOCS function using a commercially available rapid TEOAE measurement system.
authors.affiliation: Kresge Hearing Research Laboratory of the South, New Orleans, LA 70112, USA. tmorle@lsuhsc.edu
authors.forename: T
authors.initials: T
authors.lastname: Morlet
authors.forename: A
authors.initials: A
authors.lastname: Hamburger
authors.forename: J
authors.initials: J
authors.lastname: Kuint
authors.forename: D
authors.initials: D
authors.lastname: Ari-Even Roth
authors.forename: M
authors.initials: M
authors.lastname: Gartner
authors.forename: C
authors.initials: C
authors.lastname: Muchnik
authors.forename: L
authors.initials: L
authors.lastname: Collet
authors.forename: M
authors.initials: M
authors.lastname: Hildesheimer
mesh_terms: D000161:Acoustic Stimulation; D001300:Audiometry, Evoked Response / Q000379:methods*; D003051:Cochlea / Q000294:innervation* / Q000502:physiology; D004525:Efferent Pathways / Q000502:physiology; D005260:Female; D018072:Hair Cells, Auditory, Outer / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn / Q000502:physiology*; D007234:Infant, Premature / Q000502:physiology*; D008297:Male; D015997:Neonatal Screening / Q000379:methods; D009847:Olivary Nucleus / Q000502:physiology*; D017084:Otoacoustic Emissions, Spontaneous