Tuberculous meningitis in adults: a four-year review during 1997-2000.
We reviewed the charts of all HIV-negative patients 15 years of age or older in whom tuberculous meningitis was diagnosed and treated without corticosteroids at Srinagarind Hospital, Khon Kaen, Thailand during the period of 1997-2000. Forty-five patients were included in this study. The clinical manifestations were subacute to chronic meningitis and they presented in stages 1 and 2, except one case which was in stage 3. All patients were treated with a 6-month course of chemotherapy with good clinical outcomes. The mortality rate was 2.2% and the percent of residual neurological deficits after treatment was 6.7%. The review showed the good clinical outcomes can be had without adjunctive corticosteroid.
Chotmongkol
Verajit
V
Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Panthavasit
Jedsada
J
Tiamkao
Somsak
S
Jitpimolmard
Suthipun
S
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000995:Antitubercular Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013785:Thailand / Q000453:epidemiology; D016896:Treatment Outcome; D014390:Tuberculosis, Meningeal / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology* / Q000401:mortality
D000995:Antitubercular Agents