[Study on the preparation of rapid-dissoluted EGb droppills].
OBJECTIVE
To study the formulation and technique of preparation of rapid-dissoluted EGb (Extract of Ginkgo biloba) droppills.


METHODS
Taking the dissolution percentage of total flavonoids in EGb and weight variation as index, the formulation and technique of EGb droppills were optimized by the orthogonal experiment.


RESULTS
T50 was 3.62 min and mean weight variation was 2.80%.


CONCLUSIONS
Rapid-dissoluted EGb droppills can increase the dissoluting rate distinctly and reach the purpose of preparation.
Ge
Yue-bin
YB
School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, Liaojing, China.
Chen
Da-wei
DW
Li
Zhi-bo
ZB
Ma
Yan
Y
Song
Hua-xian
HX
Hu
Hai-yang
HY
D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000737:chemistry / Q000302:isolation & purification; D005419:Flavonoids / Q000032:analysis; D020441:Ginkgo biloba / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D012995:Solubility; D013678:Technology, Pharmaceutical / Q000379:methods*
D004365:Drugs, Chinese Herbal; D005419:Flavonoids