Proton pumping ATPases and diverse inside-acidic compartments.
Proton-translocating ATPases are essential cellular energy converters that transduce the chemical energy of ATP hydrolysis into transmembrane proton electrochemical potential differences. The structures, catalytic mechanism, and cellular functions of three major classes of ATPases including the F-type, V-type, and P-type ATPase are discussed in this review. Physiological roles of the acidic organelles and compartments contained are also discussed.
Futai
Masamitsu
M
Division of Biological Sciences, Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki City, Osaka 567-0047, Japan. m-futai@sanken.osaka-u.ac.jp
Sun-Wada
Ge-Hong
GH
Wada
Yoh
Y
D000251:Adenosine Triphosphatases / Q000737:chemistry / Q000145:classification / Q000502:physiology; D000818:Animals; D002384:Catalysis; D002451:Cell Compartmentation / Q000502:physiology; D006863:Hydrogen-Ion Concentration; D015388:Organelles / Q000502:physiology; D017494:Proton Pumps / Q000145:classification / Q000502:physiology; D012399:Rotation
D017494:Proton Pumps; D000251:Adenosine Triphosphatases