title: [Indications for blood transfusion during orthopedic surgery].
abstract: Ageing of the population increases the number of large orthopedic surgical interventions in elder people. High perioperative blood loss together with a reduced tolerance to anemia increase the transfusion probability in this patient subgroup. The expected cost explosion in the transfusion system (cost intensive quality management, imbalance between the number of donors and recipients) as well as the remaining transfusion related risk of hemolysis, infection and immunosuppression reflect the high socio-economic significance of the development of institutional transfusion programs. The present article summarizes: (1) the (patho-) physiology of anemia compensation, (2) the decision making for transfusion in healthy patients and patients with cardiovascular disease, and (3) the currently applied pre- and intraoperative techniques to reduce allogeneic transfusion in orthopedic patients.
authors.affiliation: Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie der Johann-Wolfgang-Goethe-Universität Frankfurt. habler@em.uni-frankfurt.de
authors.forename: O
authors.initials: O
authors.lastname: Habler
authors.forename: J
authors.initials: J
authors.lastname: Meier
authors.forename: A
authors.initials: A
authors.lastname: Pape
authors.forename: B
authors.initials: B
authors.lastname: Zwissler
mesh_terms: D000368:Aged; D016063:Blood Loss, Surgical / Q000503:physiopathology; D001803:Blood Transfusion / Q000191:economics; D001804:Blood Transfusion, Autologous / Q000191:economics; D000075202:Contraindications; D005858:Germany; D006400:Hematocrit; D006438:Hemodilution / Q000191:economics; D006452:Hemoglobinometry; D006801:Humans; D019637:Orthopedic Procedures / Q000191:economics; D012307:Risk Factors; D017749:Total Quality Management / Q000191:economics