title: Visualising very large phylogenetic trees in three dimensional hyperbolic space.
abstract: BACKGROUND
  Common existing phylogenetic tree visualisation tools are not able to display readable trees with more than a few thousand nodes. These existing methodologies are based in two dimensional space.
  
  
  RESULTS
  We introduce the idea of visualising phylogenetic trees in three dimensional hyperbolic space with the Walrus graph visualisation tool and have developed a conversion tool that enables the conversion of standard phylogenetic tree formats to Walrus' format. With Walrus, it becomes possible to visualise and navigate phylogenetic trees with more than 100,000 nodes.
  
  
  CONCLUSIONS
  Walrus enables desktop visualisation of very large phylogenetic trees in 3 dimensional hyperbolic space. This application is potentially useful for visualisation of the tree of life and for functional genomics derivatives, like The Adaptive Evolution Database (TAED).
authors.affiliation: Computational Biology Unit Bergen Centre for Computational Science University of Bergen, 5020 Bergen, Norway. tim@ii.uib.no
authors.forename: Timothy
authors.initials: T
authors.lastname: Hughes
authors.forename: Young
authors.initials: Y
authors.lastname: Hyun
authors.forename: David A
authors.initials: DA
authors.lastname: Liberles
mesh_terms: D000818:Animals; D001105:Archaea / Q000145:classification / Q000166:cytology; D001419:Bacteria / Q000145:classification / Q000166:cytology; D002965:Classification / Q000379:methods; D019295:Computational Biology / Q000379:methods; D003196:Computer Graphics / Q000639:trends*; D016208:Databases, Factual; D005057:Eukaryotic Cells / Q000145:classification; D010802:Phylogeny; D011323:Primates / Q000145:classification; D011381:Programming Languages; D012984:Software; D014584:User-Computer Interface