Influence of the management of asystolic donors on kidney transplantation outcome.
Two methods of donor management were analysed, namely, with and without in situ cooling perfusion of the kidney in an attempt to determine the optimal management and preservation methods for asystolic kidney donors. The group of recipients of in situ cooling perfusion kidneys showed more days of oliguria (P <.05), needed more dialysis sessions (P <.05), and showed no transplant function during the first week after surgery. This group also had a greater probability of acute rejection (P =.071) and a higher rate of nonfunctioning grafts (P =.09). We conclude that in situ cooling perfusion of asystolic kidney donors impairs graft function.
Sacristán-Lista
F
F
Departments of Pathology, Complexo Hospitalario Universitario Juan Canalejo, A Coruña, Spain. pirulo@canalejo.org
Mosquera-Reboredo
J
J
Vázquez-Martul
E
E
Alonso-Hernández
A
A
Fernández-Rivera
C
C
Fernández-Garcia
A
A
Sánchez-Ibáñez
J
J
Pértega-Diaz
S
S
D000328:Adult; D000368:Aged; D005260:Female; D006323:Heart Arrest; D006801:Humans; D016030:Kidney Transplantation / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D011183:Postoperative Complications / Q000145:classification / Q000453:epidemiology; D012189:Retrospective Studies; D014019:Tissue Donors; D020858:Tissue and Organ Harvesting / Q000379:methods*; D016896:Treatment Outcome