title: Melanin pigmented oncocytic metaplasia of the nasopharynx.
abstract: A case of melanin pigmented oncocytic metaplasia is reported. A 62-year-old man presented with a history of discomfort of the ear of a 2 weeks' duration. Nasoscopic examination revealed a black nodule of about 5mm at the left Eustachian opening, and several black spots were discovered around the bilateral torus tubarius. The nodule was biopsied to determine the histology. Microscopically, there were oncocytic cells with abundant pigmented granules showing glandular pattern. Such a pigmented variant of benign oncocytic lesion is very rare.
authors.affiliation: Department of Otolaryngology, Sapporo Medical University School of Medicine, Chuou-ku, Sapporo 060-8556, Japan. kent@sapmed.ac.jp
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Takano
authors.forename: Jun
authors.initials: J
authors.lastname: Sato
authors.forename: Hideaki
authors.initials: H
authors.lastname: Shirasaki
authors.forename: Norikazu
authors.initials: N
authors.lastname: Yamazaki
authors.forename: Katsufumi
authors.initials: K
authors.lastname: Hoki
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Himi
mesh_terms: D005064:Eustachian Tube / Q000473:pathology; D006801:Humans; D008297:Male; D008543:Melanins / Q000032:analysis*; D008679:Metaplasia / Q000473:pathology; D008875:Middle Aged; D009302:Nasopharyngeal Diseases / Q000473:pathology*; D009305:Nasopharynx / Q000737:chemistry / Q000473:pathology*; D024862:Oxyphil Cells / Q000473:pathology*
chemical_list: D008543:Melanins