title: Benign osteoma with Gardner syndrome: review of the literature and report of a case.
abstract: Gardner syndrome, a variant of familial adenomatous polyposis, is an autosomal dominant disease characterized by gastrointestinal polyps that develop in the colon as well as in the stomach and upper intestine (duodenum), multiple osteomas, and skin and soft tissue tumors. Cutaneous findings include epidermoid cysts, desmoid tumors, and other benign tumors. Polyps have a 100% risk of undergoing malignant transformation; consequently, early identification and therapy of the disease are critical. Osteoma is a benign neoplasm of bone tissue that is characterized by slow continuous growth and is the most common accompanying bone lesion seen in Gardner syndrome. The authors report a case of Gardner syndrome that was operated on because of the mandibular osteoma.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Ege University, Bornova, 35100 Izmir, Turkey. ubilkay@hotmail.com
authors.forename: Ufuk
authors.initials: U
authors.lastname: Bilkay
authors.forename: Ozgur
authors.initials: O
authors.lastname: Erdem
authors.forename: Cuneyt
authors.initials: C
authors.lastname: Ozek
authors.forename: Evren
authors.initials: E
authors.lastname: Helvaci
authors.forename: Kamil
authors.initials: K
authors.lastname: Kilic
authors.forename: Yesim
authors.initials: Y
authors.lastname: Ertan
authors.forename: Tahir
authors.initials: T
authors.lastname: Gurler
mesh_terms: D005736:Gardner Syndrome / Q000235:genetics / Q000473:pathology*; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000235:genetics / Q000601:surgery*; D008441:Maxillary Neoplasms / Q000473:pathology; D008875:Middle Aged; D010016:Osteoma / Q000235:genetics / Q000601:surgery*; D012888:Skull Neoplasms / Q000473:pathology; D013100:Sphenoid Bone / Q000473:pathology