"First uterine pass effect" is observed when estradiol is placed in the upper but not lower third of the vagina.
In postmenopausal women, the "first uterine pass effect" is seen when E(2) is placed in the upper but not lower third of the vagina.
Cicinelli
Ettore
E
De Ziegler
Dominique
D
Morgese
Stella
S
Bulletti
Carlo
C
Luisi
Diletta
D
Schonauer
Luca Maria
LM
D001284:Atrophy; D004958:Estradiol / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause; D013607:Tablets; D014621:Vagina / Q000187:drug effects* / Q000473:pathology
D013607:Tablets; D004958:Estradiol