Clinical efficacy and prediction of response to granulocyte transfusion therapy for patients with neutropenia-related infections.
We investigated the efficacy of transfusing granulocytes into 32 patients with severe neutropenia-related infections and the factors that predict response to this therapy. Our findings suggest that granulocyte transfusion therapy is useful for treating neutropenic patients with fungal infections and that 99mTc-HMPAO-granulocyte scintigraphy can be used to predict response to granulocyte transfusion therapy.
Lee
Je-Jung
JJ
Song
Ho-Chun
HC
Chung
Ik-Joo
IJ
Bom
Hee-Seung
HS
Cho
Duck
D
Kim
Hyeoung-Joon
HJ
D000328:Adult; D006098:Granulocytes / Q000637:transplantation*; D006801:Humans; D016867:Immunocompromised Host; D017708:Leukocyte Transfusion; D009181:Mycoses / Q000276:immunology* / Q000628:therapy*; D009503:Neutropenia / Q000382:microbiology*; D011446:Prospective Studies; D016896:Treatment Outcome