title: Failure to thrive and cognitive development in toddlers with infantile anorexia.
abstract: OBJECTIVE
  The goal of this study was to examine the relative contributions of growth deficiency and psychosocial factors to cognitive development in toddlers with infantile anorexia.
  
  
  METHODS
  Eighty-eight toddlers, ranging in age from 12 to 33 months, were enrolled in this study. Toddlers were evaluated by 2 child psychiatrists and placed into 1 of 3 groups: infantile anorexia, picky eater, and healthy eater. All 3 groups were matched for age, race, gender, and socioeconomic status (SES). Toddlers underwent nutritional evaluations and cognitive assessments with the Bayley Scales of Infant Development. Toddlers and their mothers were also videotaped during feeding and play interactions, which later were rated independently by 2 observers.
  
  
  RESULTS
  On average, toddlers with infantile anorexia performed within the normal range of cognitive development. However, the Mental Developmental Index (MDI) scores of the healthy eater group (MDI = 110) were significantly higher than those of the infantile anorexia (MDI = 99) and picky eater (MDI = 96) groups. Within the infantile anorexia group, correlations between MDI scores and the toddlers' percentage of ideal body weight approached statistical significance (r =.32). Across all groups, the toddlers' MDI scores were associated with the quality of mother-child interactions, SES level, and maternal education level. Collectively, these variables explained 22% of the variance in MDI scores.
  
  
  CONCLUSIONS
  This study demonstrated that psychosocial factors, such as mother-toddler interactions, maternal education level, and SES level, are related to the cognitive development of toddlers with feeding problems and explain more unique variance in MDI scores than nutritional status.
authors.affiliation: Department of Psychiatry, Children's National Medical Center, Washington, DC 20010, USA. ichatoor@cnmc.org
authors.forename: Irene
authors.initials: I
authors.lastname: Chatoor
authors.forename: Jaclyn
authors.initials: J
authors.lastname: Surles
authors.forename: Jody
authors.initials: J
authors.lastname: Ganiban
authors.forename: Leila
authors.initials: L
authors.lastname: Beker
authors.forename: Laura McWade
authors.initials: LM
authors.lastname: Paez
authors.forename: Benny
authors.initials: B
authors.lastname: Kerzner
mesh_terms: D000855:Anorexia / Q000150:complications / Q000503:physiopathology*; D002657:Child Development; D002675:Child, Preschool; D003072:Cognition Disorders / Q000209:etiology*; D004522:Educational Status; D005183:Failure to Thrive / Q000209:etiology*; D006801:Humans; D007223:Infant; D008425:Maternal Behavior; D012959:Socioeconomic Factors