title: Orthotopic liver transplantation for acute liver failure resulting from "acute fatty liver of pregnancy".
abstract: Steatosis of the liver, demonstrating itself as the acute liver failure during the third trimester of pregnancy (Acute Fatty Liver of Pregnancy--AFLP) is a rarely observed liver pathology. Herewith we describe the case of a 19-years old pregnant patient with this rare disease. The authors present the clinical course, dynamics, diagnostics, and outcome of treatment in this unique case. In this patient the ultimate treatment chosen was the liver transplantation. The opinions, concerning liver transplantation in AFLP (expressed in the world literature) are somewhat controversial. This paper presents the first case of AFLP treatment with orthotopic liver transplantation (OLTx) in Poland.
authors.affiliation: Department General, Transplantation and Hepatic Surgery, Medical University of Warsaw, Poland.
authors.forename: Piotr
authors.initials: P
authors.lastname: Remiszewski
authors.forename: Jacek
authors.initials: J
authors.lastname: Pawlak
authors.forename: Anna
authors.initials: A
authors.lastname: Skwarek
authors.forename: Ireneusz
authors.initials: I
authors.lastname: Grzelak
authors.forename: Waldemar
authors.initials: W
authors.lastname: Patkowski
authors.forename: Mariusz
authors.initials: M
authors.lastname: Grodzicki
authors.forename: Marek
authors.initials: M
authors.lastname: Krawczyk
authors.forename: Dorota
authors.initials: D
authors.lastname: Giercuszkiewicz
authors.forename: Lech
authors.initials: L
authors.lastname: Podciechowski
authors.forename: Jan
authors.initials: J
authors.lastname: Wilczyński
mesh_terms: D000208:Acute Disease; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D005234:Fatty Liver / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016031:Liver Transplantation / Q000379:methods*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000601:surgery*; D016559:Tacrolimus / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D016559:Tacrolimus