title: TRAM flap breast reconstruction: tumescent technique reduces blood loss and transfusion requirement.
abstract: The tumescent technique has been shown to be efficacious in reducing both operative and postoperative bleeding without significant deleterious side effects in suction lipectomy. In this study, the effects of the tumescent technique on postoperative complications in transverse rectus abdominis myocutaneous (TRAM) flap breast reconstruction are investigated. All women who underwent a TRAM flap breast reconstruction by the senior author (J.B.) at the Emory Clinic during the years 1990 to 1996 were pooled (n = 386). Any woman who had a preincision infiltration of 0.25% epinephrine-containing saline solution (>200 cc) around the donor site was included in the tumescent group (n = 59). Medical records were reviewed, and rates of partial flap loss, fat necrosis (> or =10 percent flap volume), flap full-thickness skin loss, donor-site complication (skin loss, hernia, or infection), and blood transfusion were determined. Group rates were compared. The infiltrated group had a significantly lower transfusion rate as compared with the control group (0.34 units versus 1.32 units, p < 0.001). The rates of partial flap loss and fat necrosis were less in the tumescent group, but not significantly (0 percent versus 4 percent, p = 0.232; and 1.7 percent versus 10.4 percent, p = 0.058). There were no significant differences in the incidence of full-thickness skin loss or donor-site complications. Donor-site infiltration before incision with a 0.25% epinephrine-containing saline solution significantly reduced the transfusion requirement in TRAM flap breast reconstruction patients without adversely affecting either breast mound or abdominal donor-site complication rates.
authors.affiliation: Emory Plastic Surgery, Emory University, Atlanta, GA, USA. plaktp@vmmc.org
authors.forename: Keith T
authors.initials: KT
authors.lastname: Paige
authors.forename: John
authors.initials: J
authors.lastname: Bostwick
authors.forename: Jean Timble
authors.initials: JT
authors.lastname: Bried
mesh_terms: D034861:Abdominal Wall; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001803:Blood Transfusion; D004837:Epinephrine / Q000008:administration & dosage*; D005218:Fat Necrosis / Q000209:etiology; D005260:Female; D006085:Graft Survival; D006801:Humans; D007260:Infusion Pumps; D016462:Mammaplasty / Q000379:methods*; D011183:Postoperative Complications; D012189:Retrospective Studies; D012965:Sodium Chloride / Q000008:administration & dosage*; D013524:Surgical Flaps; D020858:Tissue and Organ Harvesting / Q000009:adverse effects / Q000379:methods; D014662:Vasoconstrictor Agents / Q000008:administration & dosage*
chemical_list: D014662:Vasoconstrictor Agents; D012965:Sodium Chloride; D004837:Epinephrine