New HLA-B alleles detected by polymerase chain reaction-sequence-specific oligonucleotide typing: HLA-B*0725, B*0728, and B*3808.
Three novel alleles, human leukocyte antigen (HLA)-B*0725, B*0728, and B*3808, were discovered during routine genotyping of samples for the Australian Bone Marrow Donor Registry and Australian Cord Blood Bank. The new alleles contain amino acid changes in the antigen-binding site of the expressed HLA protein, which may alter the antigen-binding properties of the functional protein.
Dodd
R
R
Molecular Genetics, Tissue Typing, Australian Red Cross Blood Service, Sydney, Australia.
Hersee
J
J
Greville
W D
WD
Chapman
G
G
Taverniti
A
A
Le
T
T
Wallace
R
R
Kennedy
A
A
Dunckley
H
H
D001483:Base Sequence; D015235:HLA-B Antigens / Q000235:genetics*; D059945:HLA-B38 Antigen; D015793:HLA-B7 Antigen; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction
D015235:HLA-B Antigens; C425023:HLA-B*07 antigen; C495074:HLA-B*07:25 antigen; C495075:HLA-B*07:28 antigen; C495076:HLA-B*38:08 antigen; D059945:HLA-B38 Antigen; D015793:HLA-B7 Antigen