title: Taste function in Sjögren's syndrome patients with special reference to clinical tests.
abstract: OBJECTIVE
  We analyzed the correlation between taste functions and clinical features in patients with Sjögren's syndrome (SS).
  
  
  METHODS
  Sixty-three patients were divided into two groups: group A consisting of patients with primary or secondary SS of the European classification, and group B consisting of non-SS complaining of dry eye and mouth.
  
  
  RESULTS
  Eighteen percent of the group A patients and 11% of the group B patients complained of taste disorders. Electrogustometric examination detected taste disorders in 27% of the group A patients and 38% of the group B patients, while the filter paper disc method showed taste disorders in 30% of group A and 40% of group B. In group A, unstimulated and stimulated salivary flows were correlated with the ability to discriminate taste analyzed by the filter paper disc method, but not with the taste electrogustometric threshold. Serum zinc concentration was not significantly correlated with taste disorders in either group.
  
  
  CONCLUSIONS
  Our findings showed that SS patients presented taste disorders less frequently than previously reported, and we speculated that taste disorder found in SS patients were due to the salivary flow deficiency that might prevent substances from reaching the taste buds.
authors.affiliation: Department of Otolaryngology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya City, Hyogo 663-8501, Japan. a-negoro@hyo-med.ac.jp
authors.forename: Atsushi
authors.initials: A
authors.lastname: Negoro
authors.forename: Masanori
authors.initials: M
authors.lastname: Umemoto
authors.forename: Megumi
authors.initials: M
authors.lastname: Fujii
authors.forename: Masao
authors.initials: M
authors.lastname: Kakibuchi
authors.forename: Tomonori
authors.initials: T
authors.lastname: Terada
authors.forename: Naoaki
authors.initials: N
authors.lastname: Hashimoto
authors.forename: Masafumi
authors.initials: M
authors.lastname: Sakagami
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D012463:Saliva / Q000378:metabolism; D012469:Salivary Glands / Q000000981:diagnostic imaging / Q000378:metabolism / Q000503:physiopathology*; D012859:Sjogren's Syndrome / Q000145:classification / Q000150:complications / Q000503:physiopathology*; D011795:Surveys and Questionnaires; D013649:Taste / Q000502:physiology*; D013651:Taste Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D013652:Taste Threshold; D014059:Tongue / Q000473:pathology; D015032:Zinc / Q000032:analysis
chemical_list: D015032:Zinc