Epidemiologic study of the association between human T-cell lymphotropic virus type 1 and Strongyloides stercoralis infection in female blood donors (Guadeloupe, French West Indies).
This case control study was conducted among female blood donors in Guadeloupe. A total of 85 HTLV-1 positive subjects were matched by age (+/- 5 years) in a 1:3 ratio to 255 HTLV-1 negative controls. The mean age was 48.5 and 48.9 years respectively. Ethnic, environmental and socio-economic risk factors were studied. Four risk factors were found independently associated with HTLV-1 seropositivity: Strongyloides stercoralis antibodies (OR = 3.6, CI 1.8, 7.3), low socio-economic status (OR = 2.0 CI 1.0, 4.0), low educational level (OR = 2.0 CI 1.0, 4.0) and agricultural activity (OR = 2.8 CI 1.4, 5.6). This logistic regression analysis demonstrates the reality of the association between HTLV-1 carriers and Strongyloides stercoralis, and its association with socio-economic and environmental risk factors.
Courouble
G
G
Laboratory of Parasitology, Infectious Diseases Service, Medical Department of Information, Pointe-à-Pitre/Abymes University Hospital, Guadeloupe, French West Indies. gcourouble@free.fr
Rouet
F
F
Herrmann-Storck
C
C
Nicolas
M
M
Candolfi
E
E
Deloumeaux
J
J
Carme
B
B
D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D001782:Blood Donors; D016022:Case-Control Studies; D005260:Female; D019430:Guadeloupe / Q000453:epidemiology; D015490:HTLV-I Infections / Q000150:complications* / Q000453:epidemiology; D015368:Human T-lymphotropic virus 1 / Q000276:immunology; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D012959:Socioeconomic Factors; D017171:Strongyloides stercoralis / Q000276:immunology; D013322:Strongyloidiasis / Q000150:complications* / Q000453:epidemiology
D000909:Antibodies, Helminth; D000914:Antibodies, Viral