title: Mammary lesions associated with bovine herpesvirus type 4 in a cow with clinical mastitis.
abstract: Intranuclear eosinophilic inclusion bodies were seen in the lactiferous duct and sinus epithelium of mammary tissues collected from a cow with clinical mastitis. Transmission electron microscopy revealed herpesvirus particles in these cells. Immunolabeling against anti bovine herpesvirus type 4 (BHV-4) rabbit serum was detected in nuclei that had intranuclear inclusion bodies. In addition, BHV-4 was isolated from the mammary tissue. The viral DNA was detected by nested PCR from the same tissue. This is the first report to describe mammary lesions in association with BHV-4.
authors.affiliation: Fukushima Prefectural Kentyu Livestock Hygiene Service Center, Koriyama, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Miyano
authors.forename: Makoto
authors.initials: M
authors.lastname: Haritani
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sentsui
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Tsuboi
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Tanimura
authors.forename: Kumiko M
authors.initials: KM
authors.lastname: Kimura
authors.forename: Masaru
authors.initials: M
authors.lastname: Kobayashi
authors.forename: Naoki
authors.initials: N
authors.lastname: Obara
authors.forename: Yuzuru
authors.initials: Y
authors.lastname: Akimoto
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology* / Q000821:virology*; D006566:Herpesviridae Infections / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D026021:Herpesvirus 4, Bovine / Q000648:ultrastructure*; D007150:Immunohistochemistry; D007181:Inclusion Bodies, Viral / Q000473:pathology*; D008321:Mammary Glands, Animal / Q000473:pathology / Q000821:virology; D008414:Mastitis, Bovine / Q000150:complications / Q000473:pathology* / Q000821:virology; D008854:Microscopy, Electron; D016133:Polymerase Chain Reaction; D014412:Tumor Virus Infections / Q000150:complications / Q000473:pathology / Q000662:veterinary*