Neutrophilic panniculitis with myelodysplastic syndromes presenting as pustulosis: case report and review of the literature.
Neutrophilic panniculitis associated with myelodysplastic syndromes is rare. We report a 59-year-old patient who initially was diagnosed with myelodysplastic syndrome (MDS) and developed a sudden onset of widespread pustulosis and erythematous indurated papules. Examination of skin biopsies of a papule lesion showed dense neutrophilic infiltration limited to the subcutaneous tissue. The pustules and papules disappeared completely after treatment with systemic corticosteroids. To our knowledge, only one patient was identified by MEDLINE search of the English-language literature.
Chen
Hsiang-Cheng
HC
Division of Rheumatology/Immunology/Allergy, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China.
Kao
Woei-Yau
WY
Chang
Deh-Ming
DM
Gao
Hong-Wei
HW
Lai
Wei-Yu
WY
Lai
Jenn-Haung
JH
D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications / Q000175:diagnosis*; D015434:Panniculitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis*; D013256:Steroids / Q000627:therapeutic use; D016463:Sweet Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy
D013256:Steroids