Excitation of vibrations in microtubules in living cells.
Microtubules, which are thought to be the primary organizers of the cytoskeleton, are electrical polar structures with extraordinary elastic deformability at low stress and with energy supply from hydrolysis of guanosine triphosphate (GTP) to guanosine diphosphate (GDP). At least a part of the energy supplied from hydrolysis can excite vibrations. Energy is mainly lost by viscous damping of the surrounding cytosol. Viscous damping is diminished by a slip layer which is formed by an attracted ionic charge layer and by a thin surface layer of the microtubule. Relaxation time caused by viscous damping may be several orders of magnitude greater than period of vibrations at 10 MHz. Energy supplied to the microtubule is of the order of magnitude of 10(-14) W cm(-1) (per unit length of the microtubule).
Pokorný
J
J
Institute of Radio Engineering and Electronics, Academy of Sciences of the Czech Republic, Chaberská 57, 182 51 Prague 8, Czech Republic. pokorny@ure.cas.cz
D000818:Animals; D004548:Elasticity; D004574:Electromagnetic Fields; D004735:Energy Transfer / Q000502:physiology*; D006153:Guanosine Diphosphate / Q000378:metabolism*; D006160:Guanosine Triphosphate / Q000378:metabolism*; D006801:Humans; D006868:Hydrolysis; D008870:Microtubules / Q000502:physiology* / Q000648:ultrastructure*; D008954:Models, Biological; D014732:Vibration; D014783:Viscosity
D006153:Guanosine Diphosphate; D006160:Guanosine Triphosphate