title: Prospective association between hypotension and idiopathic chronic fatigue.
abstract: OBJECTIVE
  To determine whether there is an association between hypotension and incident cases of idiopathic chronic fatigue.
  
  
  METHODS
  A prospective study.
  
  
  METHODS
  Johns Hopkins Precursors Study.
  
  
  METHODS
  Medical students (n = 876) in graduating classes from 1948 to 1964.
  
  
  METHODS
  'Easy fatigability' reported by participants at 5- or 10-year follow-up after graduation.
  
  
  RESULTS
  The unadjusted risk in women was 5.0 (95% exact confidence interval = 1.4 to 17.4) and in men was 1.7 (95% exact confidence interval = 0.8, to 3.5).
  
  
  CONCLUSIONS
  These preliminary findings suggest that hypotension may be a risk factor for the development of idiopathic chronic fatigue in women.
authors.affiliation: Bloomberg School of Public Health and School of Medicine, Johns Hopkins University, Baltimore, Maryland 21205-2233, USA.
authors.forename: Katherine E
authors.initials: KE
authors.lastname: Lucas
authors.forename: Peter C
authors.initials: PC
authors.lastname: Rowe
authors.forename: Josef
authors.initials: J
authors.lastname: Coresh
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Klag
authors.forename: Lucy A
authors.initials: LA
authors.lastname: Meoni
authors.forename: Daniel E
authors.initials: DE
authors.lastname: Ford
mesh_terms: D000328:Adult; D016001:Confidence Intervals; D005221:Fatigue / Q000150:complications* / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007022:Hypotension / Q000453:epidemiology / Q000503:physiopathology*; D015994:Incidence; D016014:Linear Models; D008137:Longitudinal Studies; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects; D013337:Students, Medical / Q000706:statistics & numerical data; D011795:Surveys and Questionnaires; D013997:Time Factors