Effectiveness of Cyanothece spp. and Cyanospira capsulata exocellular polysaccharides as antiadhesive agents for blocking attachment of Helicobacter pylori to human gastric cells.
The effect of cyanobacterial polysaccharides (from Cyanothece spp. and Cyanospira capsulata) on the binding of Helicobacter pylori to gastric epithelial cells was evaluated. The antiadhesive action on Kato III and HeLa S3 human gastric cell lines was established.
Ascencio
F
F
Center for Biological Research, Marine Pathology Unit, La Paz, Baja California Sur 23 000, Mexico. ascencio04@cibnor.mx
Gama
N L
NL
De Philippis
R
R
Ho
B
B
D001422:Bacterial Adhesion / Q000187:drug effects*; D045744:Cell Line, Tumor; D000458:Cyanobacteria / Q000378:metabolism*; D004847:Epithelial Cells / Q000382:microbiology*; D005753:Gastric Mucosa / Q000382:microbiology*; D006367:HeLa Cells; D016480:Helicobacter pylori / Q000502:physiology*; D006801:Humans; D011135:Polysaccharides, Bacterial / Q000096:biosynthesis / Q000737:chemistry / Q000494:pharmacology*
D011135:Polysaccharides, Bacterial