[Key events in the cell cycle, their regulation and organization].
The review surveys the studies of molecular genetic mechanisms of the cell cycle control on various eukaryotic models. The major cell cycle phenomena are considered: (1) checkpoints and their role in preserving DNA integrity and fidelity of mitosis, (2) the cell oscillator model, and (3) the role of cyclins in timing of cell division and coordination of mitotic events. The main classes of regulatory proteins involved in the cell cycle are discussed in detail.
Omel'ianchuk
L V
LV
Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, 630090 Russia. ome@bionet.nsk.ru
Trunova
S A
SA
Lebedeva
L I
LI
Fedorova
S A
SA
D002453:Cell Cycle; D015003:Yeasts / Q000166:cytology / Q000235:genetics