title: MR-guided intravascular procedures: real-time parameter control and automated slice positioning with active tracking coils.
abstract: OBJECTIVE
  To implement and optimize a real-time pulse sequence and user interface to perform intravascular interventions using active catheter tracking.
  
  
  METHODS
  In magnetic resonance (MR)-guided interventions, small radio-frequency coils can be used to rapidly determine the device position (active tracking). In this work, active catheter tracking was combined with a dedicated real-time pulse sequence and user interface. The pulse sequence offered the imaging contrasts fast low angle shot (FLASH), true Fast imaging with steady state precession (TrueFISP), and projection MR digital subtraction angiography (MR-DSA), which could be selected by the radiologist from within the scanner room at any time during the intervention. Automatic slice positioning was added to the real-time pulse sequence so that the location of the tracking coils defined the image slice position and orientation. The technique was assessed in phantoms and animal experiments.
  
  
  RESULTS
  At a reaction time of 24 msec and a frame rate of three images per second, the movement of an active intravascular catheter could be monitored in the aorta and the renal arteries of a pig. With interactive contrast and orientation changes, the renal vasculature could be assessed by a fully MR-guided catheterization in less than 10 minutes.
  
  
  CONCLUSIONS
  With carefully designed active catheters, a dedicated user interface, and an optimized pulse sequence intravascular interventions can successfully be performed by a single operator from within the MR scanner room.
authors.affiliation: Deutsches Krebsforschungszentrum (dkfz), Abt. Medizinische Physik in der Radiologie (E020), Heidelberg, Germany. M.Bock@dkfz-heidelberg.de
authors.forename: Michael
authors.initials: M
authors.lastname: Bock
authors.forename: Steffen
authors.initials: S
authors.lastname: Volz
authors.forename: Sven
authors.initials: S
authors.lastname: Zühlsdorff
authors.forename: Reiner
authors.initials: R
authors.lastname: Umathum
authors.forename: Christian
authors.initials: C
authors.lastname: Fink
authors.forename: Peter
authors.initials: P
authors.lastname: Hallscheidt
authors.forename: Wolfhard
authors.initials: W
authors.lastname: Semmler
mesh_terms: D000818:Animals; D002404:Catheterization / Q000295:instrumentation* / Q000379:methods*; D004867:Equipment Design; D005260:Female; D008279:Magnetic Resonance Imaging; D023421:Models, Animal; D019047:Phantoms, Imaging; D015641:Radiography, Interventional / Q000295:instrumentation* / Q000379:methods*; D013552:Swine; D014584:User-Computer Interface