[Methods of monitoring oxidation-reduction balance and its potential role in diagnostics].
Results of the latest investigations confirm that the injury of redox homeostasis of human organism can be the starting point of many diseases. The pathogenesis of these diseases, including atherosclerosis, diabetes mellitus, chronic liver diseases, renal failure, rheumatoid arthritis and neurodegenerative diseases could be cleared up more deeply by the investigation of parameters of oxidative stress and by the observation of their changes in connection with the different organ and tissue damages. It is well known, that individuals with lowered antioxidant defences may be at greater risk of developing diseases induced by free radicals. The goal of the authors is to direct attention to the possible role of some redox parameters in detecting of general health status of the human body and in the risk assessment of the different diseases. These measurements can perhaps help the clinician in determining optimal treatment and monitoring its effectiveness.
Kocsis
Ibolya
I
Semmelweis Egyetem, Altalános Orvostudományi Kar, II. Belgyógyászati Klinika, Budapest.
Blázovics
Anna
A
Pallai
Zsolt
Z
Fehér
János
J
D000975:Antioxidants / Q000378:metabolism*; D015415:Biomarkers / Q000097:blood; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005455:Fluorescent Antibody Technique; D016166:Free Radical Scavengers / Q000097:blood / Q000378:metabolism*; D005609:Free Radicals / Q000097:blood / Q000378:metabolism*; D006801:Humans; D007124:Immunoenzyme Techniques; D008108:Liver Diseases, Alcoholic / Q000097:blood; D008163:Luminescent Measurements; D010084:Oxidation-Reduction; D018384:Oxidative Stress
D000975:Antioxidants; D015415:Biomarkers; D016166:Free Radical Scavengers; D005609:Free Radicals