title: Primary intraosseous carcinoma of the jaws arising from an odontogenic cyst--a case report.
abstract: BACKGROUND
  Squamous cell carcinoma of the jaw located purely in the bone is extremely rare. Most of these intraosseous carcinomas, also called odontogenic carcinomas are thought to arise from the epithelial lining of an odontogenic cyst.
  
  
  METHODS
  A primary intraosseous carcinoma arising from an odontogenic cyst in a 64-year-old woman is reported. No subjective symptoms were noted by the patient. Multiple retained teeth with associated presumed cystic lesions were evident in the lower jaw on a routine radiograph. Histology revealed an intraosseous carcinoma after removal of the teeth and "cystectomy". No metastasis was detected. Segmental resection of the mandible, selective neck dissection and reconstruction with an iliac bone graft was performed. The patient is free of disease after 3 years.
  
  
  CONCLUSIONS
  Although primary intraosseous carcinoma is rare, this case emphasizes the importance of careful histological examination of apparently innocuous odontogenic cysts. In addition, as malignant changes in their epithelial lining are always possible, "cystic" lesions should not only be removed but as completely as possible.
authors.affiliation: Department for Cranio-Maxillofacial and Facial Plastic Surgery, University of Cologne, Cologne 50931, Germany. m.scheer@uni-koeln.de
authors.forename: Martin
authors.initials: M
authors.lastname: Scheer
authors.forename: A M Anja M
authors.initials: AM
authors.lastname: Koch
authors.forename: Uta
authors.initials: U
authors.lastname: Drebber
authors.forename: A C Alexander C
authors.initials: AC
authors.lastname: Kübler
mesh_terms: D016025:Bone Transplantation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008197:Lymph Node Excision; D008334:Mandible / Q000601:surgery; D008336:Mandibular Diseases / Q000473:pathology* / Q000601:surgery; D008339:Mandibular Neoplasms / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D009807:Odontogenic Cysts / Q000473:pathology* / Q000601:surgery; D009808:Odontogenic Tumors / Q000473:pathology* / Q000601:surgery; D014095:Tooth, Impacted / Q000473:pathology