title: Benign renal mesenchymoma in the pediatric age group: a novel pathologic and karyotype entity.
abstract: Benign mesenchymal renal tumors are extremely rare in the pediatric age group. We report a case of a benign renal tumor composed of smooth muscle cells, adipose tissue, and areas of cartilaginous differentiation and expressing a 46,XX, t(8;10)(q21;q24) karyotype in a 13-year-old girl. Although some pediatric renal tumors show a degree of heterologous differentiation, none of them exclusively consist of these three well-differentiated mesenchymal components. The unique features of the present case were further confirmed by the karyotype changes, which to our knowledge, have never been described before in a pediatric renal tumor.
authors.affiliation: Department of Urology, University Hospitals Leuven, Leuven, Belgium.
authors.forename: Steven
authors.initials: S
authors.lastname: Joniau
authors.forename: Lieven
authors.initials: L
authors.lastname: Goeman
authors.forename: Susanne
authors.initials: S
authors.lastname: Kreuzbauer
authors.forename: Guy
authors.initials: G
authors.lastname: Bogaert
authors.forename: Paola
authors.initials: P
authors.lastname: Dal Cin
authors.forename: Raymond
authors.initials: R
authors.lastname: Oyen
authors.forename: Raf
authors.initials: R
authors.lastname: Sciot
authors.forename: Hein
authors.initials: H
authors.lastname: van Poppel
mesh_terms: D000293:Adolescent; D001064:Appendicitis / Q000601:surgery; D005260:Female; D006801:Humans; D033162:Incidental Findings; D007621:Karyotyping; D007680:Kidney Neoplasms / Q000235:genetics / Q000473:pathology*; D008637:Mesenchymoma / Q000235:genetics / Q000473:pathology*