Microcapsule modification with peroxidase-catalyzed phenol polymerization.
A biocatalytic polymer synthesis on a surface of polyelectrolyte microcapsules was studied. Horseradish peroxidase assembled in nanoorganized capsule walls by alternate adsorption with linear polyions retains its activity in reactions of enzyme-catalyzed polymerization of 4-oxyphenols. It allowed controllable synthesis of a phenolic polymer layer on microcapsule walls using an outermost surface peroxidase layer as a template. By varying the phenol type, buffer pH, and reaction component concentrations, the phenolic polymer coating of the capsules with a thickness in the range 20-50 nm was formed. The polymeric products are fluorescent, which provided a good opportunity for confocal image analysis of the capsule wall structure and the attached layer. The influence of a phenolic polymer layer on the permeability of the capsule walls was investigated.
Shutava
Tatsiana
T
Institute for Micromanufacturing and Chemistry Program, Louisiana Tech University, Ruston, Louisiana 71272, USA.
Zheng
Zhiguo
Z
John
Vijay
V
Lvov
Yuri
Y
D002384:Catalysis; D004573:Electrolytes; D018625:Microscopy, Atomic Force; D018613:Microscopy, Confocal; D010636:Phenols / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
D004573:Electrolytes; D010636:Phenols; D011108:Polymers