First-year outcomes of beating heart coronary artery bypass grafting using proximal mechanical connectors.
BACKGROUND
To determine the extended results of mechanical connectors we compared the 1-year outcomes of patients having beating heart coronary artery bypass surgery with at least one sutured or mechanically connected proximal vein graft anastomosis.


METHODS
From May 2001 to December 2001, 166 patients were identified as having undergone off-pump bypass grafting utilizing at least one St. Jude symmetry aortic connector (St Jude Medical Anastomotic Technology Group, St. Paul, MN). Follow-up for major adverse cardiac events (MACEs), which is defined as cardiac mortality, myocardial infarction, or revascularization of a previous target vessel, was obtained on 162 patients (97.6%). A control group of 159 patients was identified from a cohort of patients having beating heart surgery with one or more sutured proximal vein graft anastomosis in the preceding year. The MACE follow-ups were obtained in 136 patients (85.6%) by direct telephone contact.


RESULTS
Patients with connectors showed an accelerated number of MACEs beginning approximately 180 days from the time of surgery and stabilizing at approximately 300 days. Logistic regression analysis identified the presence of diabetes as a significant preoperative risk factor predisposing patients to earlier onset of MACEs (p = 0.03) with an odds ratio of 2.9 (95% confidence interval, 1.1 to 7.6). Insulin dependent diabetics showed no differences between connector and control patients in the frequency or timing of MACEs. Connector patients using oral hypoglycemic agents demonstrated a significant deviation (p = 0.01) from a similar control population in the prevalence and timing of MACEs.


CONCLUSIONS
Connector patients showed an increased incidence of early MACEs. These events were characterized by an increased requirement for early target vessel revascularization and were predominantly in noninsulin-dependent diabetics.
Dewey
Todd M
TM
Cardiopulmonary Research Science and Technology Institute, Dallas, Texas 75230, USA. tdewey@csant.com
Crumrine
Katherine
K
Herbert
Morley A
MA
Leonard
Allison
A
Prince
Syma L
SL
Worley
Christina
C
Edgerton
James R
JR
Magee
Mitchell J
MJ
Mack
Michael J
MJ
D000368:Aged; D000714:Anastomosis, Surgical / Q000295:instrumentation*; D001026:Coronary Artery Bypass / Q000295:instrumentation* / Q000379:methods; D003327:Coronary Disease / Q000601:surgery; D003925:Diabetic Angiopathies / Q000601:surgery; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D019736:Prostheses and Implants; D012307:Risk Factors; D012501:Saphenous Vein / Q000637:transplantation; D013537:Sutures; D016896:Treatment Outcome