title: [Study on odontal & periodontal tissue of guinea pigs, dogs and monkeys].
abstract: OBJECTIVE
  To evaluate the different application of different experimental animals in studies of periodontal diseases.
  
  
  METHODS
  The odontal and the periodontal tissues of guinea pigs, dogs and monkeys were studied by gross specimen, X ray and histological observation.
  
  
  RESULTS
  The most suitable sites of guinea pigs for periodontal study is incisor just because of their small oral fissure, but the keratinized epithelium of gingival sulcus may affect their inflammatory reaction. As the occurring of spaces from the 3rd to 5th tooth of dogs, artificial intrabony pocket can be made, and their thick root canals are suitable for pulp and periapical study. The monkeys are the ideal experimental animals due to their similarities to human, but it is too expensive to be widely used.
  
  
  CONCLUSIONS
  Each kind of animal has their own characteristics. The key is to select experimental animal according to the objective of our different studies.
authors.affiliation: School of Stomatology, Shanghai Second Medical University, Shanghai 200011, China.
authors.forename: Li-zhen
authors.initials: LZ
authors.lastname: Wang
authors.forename: De-yi
authors.initials: DY
authors.lastname: Li
mesh_terms: D000818:Animals; D004285:Dogs; D005260:Female; D006168:Guinea Pigs; D000882:Haplorhini; D008297:Male; D023421:Models, Animal; D010519:Periodontium / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D011859:Radiography; D014070:Tooth / Q000033:anatomy & histology* / Q000000981:diagnostic imaging