title: The distribution of serotonin transporter immunoreactivity in hippocampal formation in monkeys and rats.
abstract: To elucidate the anatomical distribution of the serotonergic neurotransmitter system, we identified serotonin transporter (5-HTT) in the hippocampus of rats and monkeys by immunohistochemistry. A widespread and heterogeneous distribution of 5-HTT-immunoreactive fine fibers was noted in the rat brain. However, in monkeys, punctuate 5-HTT-immunoreactive deposits and fewer fibers were observed. The species difference in 5-HTT immunohistochemical staining pattern may be caused by differences in localization of 5-HTT between species.
authors.affiliation: Department of Psychiatry, Showa University School of Medicine, 1-5-8, Hatanodai, Shinagawa, Tokyo 142-8666, Japan. owashi-psy@umin.ac.jp
authors.forename: Toshimi
authors.initials: T
authors.lastname: Owashi
authors.forename: Shuji
authors.initials: S
authors.lastname: Iritani
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Niizato
authors.forename: Kenji
authors.initials: K
authors.lastname: Ikeda
authors.forename: Kunitoshi
authors.initials: K
authors.lastname: Kamijima
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000096:biosynthesis*; D006624:Hippocampus / Q000033:anatomy & histology / Q000166:cytology / Q000378:metabolism*; D007150:Immunohistochemistry; D008251:Macaca; D008562:Membrane Glycoproteins / Q000096:biosynthesis*; D026901:Membrane Transport Proteins; D009412:Nerve Fibers / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000096:biosynthesis*; D009474:Neurons / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D012701:Serotonin / Q000378:metabolism*; D050486:Serotonin Plasma Membrane Transport Proteins; D013045:Species Specificity
chemical_list: D002352:Carrier Proteins; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; D050486:Serotonin Plasma Membrane Transport Proteins; C493232:Slc6a4 protein, rat; D012701:Serotonin