[Effect of toxic substances in the environment on reproduction].
OBJECTIVE
To summarize the findings about the influence of some xenobiotics on human reproduction, especially infertility.


METHODS
Review article.


METHODS
The Department of Obstetrics and Gynecology, 1st Medical Faculty, Charles University and the General Faculty Hospital, Prague


METHODS
Analysis of literature.


RESULTS
A review about the influence of some xenobiotics on human reproduction was given. In some there is a possible negative influence on the results of in vitro fertilisation program. It is a question of hormone disruptors, some heavy metals, some organic solvents, pesticides and smoking of cigarettes.


CONCLUSIONS
In most of these xenobiotics there is direct evidence of their negative influence on reproduction and the results of in vitro fertilisation program. Therefore it is worth to continue in this evaluation.
Drbohlav
P
P
Gynekologicko-porodnická klinika, 1. LF UK a VFN, Praha.
Bencko
V
V
Masata
J
J
Jirsová
S
S
D004785:Environmental Pollutants / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000139:chemically induced; D011247:Pregnancy / Q000187:drug effects; D012098:Reproduction / Q000187:drug effects*; D013723:Teratogens; D015262:Xenobiotics / Q000009:adverse effects*
D004785:Environmental Pollutants; D013723:Teratogens; D015262:Xenobiotics