title: New beauvericins, potentiators of antifungal miconazole activity, Produced by Beauveria sp. FKI-1366. II. Structure elucidation.
abstract: The structures of beauvericins D, E and F, novel potentiators of miconazole activity against Candida albicans produced by Beauveria sp. FKI 1366, were elucidated by various spectroscopic analyses including UV, NMR, and MS and degradation experiments. They have the common skeleton of the 18-membered cyclodepsipeptides.
authors.affiliation: Kitasato Institute for Life Sciences & Graduate School of Infection Control Sciences, Kitasato University 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Fukuda
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Arai
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tomoda
authors.forename: Satoshi
authors.initials: S
authors.lastname: Omura
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D000935:Antifungal Agents / Q000737:chemistry* / Q000494:pharmacology; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002851:Chromatography, High Pressure Liquid; D047630:Depsipeptides; D004357:Drug Synergism; D006868:Hydrolysis; D018942:Macrolides / Q000737:chemistry*; D008825:Miconazole / Q000494:pharmacology; D008968:Molecular Conformation; D009904:Optical Rotation; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000596:Amino Acids; D000935:Antifungal Agents; D047630:Depsipeptides; D018942:Macrolides; C485086:beauvericin D; C485087:beauvericin E; C485088:beauvericin F; D008825:Miconazole