Ajudazols, new inhibitors of the mitochondrial electron transport from Chondromyces crocatus. Production, antimicrobial activity and mechanism of action.
Kunze
Brigitte
B
GBF, German Research Centre for Biotechnology Department Natural Product Biology, Mascheroder Weg 1, D-38124 Braunschweig, Germany. bku@gbf.de
Jansen
Rolf
R
Höfle
Gerhard
G
Reichenbach
Hans
H
D000818:Animals; D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D003374:Coumarins / Q000302:isolation & purification / Q000494:pharmacology*; D004579:Electron Transport / Q000187:drug effects*; D005658:Fungi / Q000187:drug effects; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D008929:Mitochondria, Heart / Q000187:drug effects / Q000378:metabolism*; D009245:NADH Dehydrogenase / Q000378:metabolism; D020560:Proteobacteria / Q000254:growth & development / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet
D000935:Antifungal Agents; D003374:Coumarins; C485090:ajudazol A; C485091:ajudazol B; D009245:NADH Dehydrogenase