Antiretroviral drug content in products from developing countries.
Generic and brand name antiretroviral drugs are becoming increasingly available in developing countries. We analyzed 6 antiretroviral medications from 4 international sources for drug content. The active ingredient in tested drug products was within 15% of the labeled amount (range, -12% to +15%) for drugs that were properly stored.
Penzak
Scott R
SR
Department of Pharmacy, Warren G. Magnuson Clinical Center, Bethesda, Maryland, USA. spenzak@mail.cc.nih.gov
Acosta
Edward P
EP
Turner
Michele
M
Tavel
Jorge A
JA
Masur
Henry
H
D044966:Anti-Retroviral Agents / Q000032:analysis* / Q000737:chemistry; D001682:Biological Availability; D003906:Developing Countries; D004345:Drug Industry; D016568:Drugs, Generic / Q000032:analysis* / Q000737:chemistry; D006801:Humans; D013810:Therapeutic Equivalency
D044966:Anti-Retroviral Agents; D016568:Drugs, Generic