Evaluation of commercial immunoassays for detection of antibody against Helicobacter pylori in Thai dyspeptic patients.
The performance of five immunoassays for detection of immunoglobulin G antibody against Helicobacter pylori in 191 dyspeptic patients was evaluated. The sensitivities, specificities, accuracies, positive predictive values, and negative predictive values ranged from 86.32 to 97.89%, 57.95 to 72.22%, 77.02 to 83.76%, 71.54 to 77.42%, and 83.33 to 96.23%, respectively. The immunoglobulin A test kit also gave a high sensitivity and negative predictive value (95.79 and 91.40%, respectively), while the specificity was relatively low (51.14%).
Hanvivatvong
Orrawadee
O
Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand. fmedohv@md2.md.chula.ac.th
Pongpanich
Atinop
A
Thong-Ngam
Duangporn
D
Thammacharoenrach
Niramol
N
Kullavanijaya
Pinit
P
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial / Q000097:blood*; D004415:Dyspepsia / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology*; D005260:Female; D016481:Helicobacter Infections / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D007118:Immunoassay / Q000379:methods / Q000592:standards*; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D013785:Thailand
D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G