title: Uncommon anal neoplasms.
abstract: The neoplasms of the anus discussed in this article are uncommon, and therefore lack a consistent diagnostic and treatment algorithm derived from prospective clinical trial datasets. There may be an opportunity to design prospective Phase II clinical trials, with established uniform surgical pathology, surgical technique guidelines, and endpoints. The American College of Surgeons Oncology Group may have an opportunity to design and carry out controlled clinical trials for select rare anal neoplasms. Such an effort may yield modern benchmarks with which to base subsequent patient care algorithms.
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Oregon Health Sciences University, 3181 S.W. Sam Jackson Park Road, Portland, OR 97239, USA.
authors.forename: Kevin G
authors.initials: KG
authors.lastname: Billingsley
authors.forename: Lawrence E
authors.initials: LE
authors.lastname: Stern
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Lowy
authors.forename: Morton S
authors.initials: MS
authors.lastname: Kahlenberg
authors.forename: Charles R
authors.initials: CR
authors.lastname: Thomas
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery; D000465:Algorithms; D001005:Anus Neoplasms / Q000175:diagnosis / Q000601:surgery*; D001913:Bowen's Disease / Q000601:surgery; D002985:Clinical Protocols; D017322:Clinical Trials, Phase II as Topic; D006801:Humans; D008223:Lymphoma / Q000601:surgery; D008545:Melanoma / Q000601:surgery; D010145:Paget Disease, Extramammary / Q000601:surgery; D011446:Prospective Studies; D012107:Research Design