[Clinical importance of cross-reactivity between allergens].
Cross reactivity describes the development of symptoms as a consequence of the presence of specific IgE to a protein without the subject having had previous contact with that protein. Cross-reactivity depends on factors such as the individual's immune response, the type and intensity of exposure and, above all, the type of allergen. The identification of pan-allergens, which are present in various animal and vegetable sources and which show great structural and sequential similarity, even among species with little taxonomic relation, explains the existence of distinct, well-defined cross-reactivity syndromes. Knowledge of these phenomena could have important diagnostic and therapeutic consequences.
Nieto García
A
A
Unidad de Alergia Infantil, Hospital La Fe, Valencia, Spain.
Mazón Ramos
A
A
Pamies Espinosa
R
R
Caballero Gómez
L
L
Oliver Jiménez
F
F
Colomer Hernández
N
N
D000485:Allergens / Q000009:adverse effects / Q000276:immunology*; D000818:Animals; D000918:Antibody Specificity; D001717:Birds; D003429:Cross Reactions; D004531:Eggs / Q000009:adverse effects; D005512:Food Hypersensitivity / Q000209:etiology / Q000276:immunology; D005638:Fruit / Q000009:adverse effects / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology / Q000276:immunology; D007073:Immunoglobulin E / Q000276:immunology; D020315:Latex Hypersensitivity / Q000209:etiology / Q000276:immunology; D018448:Models, Immunological; D011058:Pollen / Q000009:adverse effects / Q000276:immunology; D014675:Vegetables / Q000009:adverse effects / Q000276:immunology
D000485:Allergens; D007073:Immunoglobulin E