Rectal prolapse associated with cytomegalovirus pseudomembranous colitis in a child infected by human immunodeficiency virus.
We report a newly recognized presentation of cytomegalovirus (CMV) enterocolitis in a 4-year-old girl with newly diagnosed HIV disease who presented with rectal prolapse. Gross findings showed multiple whitish punctate lesions. An endoscopic examination revealed multiple shallow ulcers and pseudomembranes along the colon. A biopsy from colonic tissues demonstrated CMV-like inclusion bodies. A direct immunofluorescence assay using specific CMV monoclonal antibody was positive for CMV-infected cells in specimens from the rectal smear.
Pancharoen
Chitsanu
C
Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. chitsanu.p@chula.ac.th
Likitnukul
Sasithorn
S
Chongsrisawat
Voranush
V
Vivatvekin
Boosba
B
Bhattarakosol
Parvapan
P
Suwangool
Pongsepeera
P
Thisyakorn
Usa
U
D002675:Child, Preschool; D003586:Cytomegalovirus Infections / Q000150:complications*; D004761:Enterocolitis, Pseudomembranous / Q000150:complications*; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D012005:Rectal Prolapse / Q000821:virology*