title: Cell biological basis for combination radiotherapy using heavy-ion beams and high-energy X-rays.
abstract: We investigated the biological effect of combining carbon-beam and X-ray in vitro. The results showed that when we employed Gray equivalent as the indication of therapeutic dose, the effects could be explained with simple additive way in the treatment plan. This fact provides important information about the combined therapy of carbon-beam and X-ray.
authors.affiliation: Division of Radiology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Demizu
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Kagawa
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Ejima
authors.forename: Hideki
authors.initials: H
authors.lastname: Nishimura
authors.forename: Ryohei
authors.initials: R
authors.lastname: Sasaki
authors.forename: Toshinori
authors.initials: T
authors.lastname: Soejima
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Yanou
authors.forename: Masakazu
authors.initials: M
authors.lastname: Shimizu
authors.forename: Yoshiya
authors.initials: Y
authors.lastname: Furusawa
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Hishikawa
authors.forename: Kazuro
authors.initials: K
authors.lastname: Sugimura
mesh_terms: D017209:Apoptosis / Q000528:radiation effects*; D002244:Carbon; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000528:radiation effects; D002478:Cells, Cultured / Q000528:radiation effects; D003131:Combined Modality Therapy; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D018499:Linear Energy Transfer / Q000528:radiation effects*; D011829:Radiation Dosage; D011882:Radiotherapy, High-Energy / Q000379:methods*; D012016:Reference Values; D012062:Relative Biological Effectiveness; D012468:Salivary Gland Neoplasms / Q000473:pathology; D012680:Sensitivity and Specificity
chemical_list: D002244:Carbon