title: Stage IIIC small cell carcinoma of the ovary: survival with conservative surgery and chemotherapy.
abstract: BACKGROUND
  Small cell carcinoma of the ovary is an aggressive tumor primarily affecting young women. Despite adjuvant therapy, the majority of patients described in the literature have fared poorly, even when the disease is diagnosed at an early stage.
  
  
  METHODS
  A 19-year-old nulligravida with small cell carcinoma of the left ovary underwent conservative surgery with staging and was found to have stage IIIC disease. She received multiagent chemotherapy with vinblastine, cisplatin, cyclophosphamide, bleomycin, doxorubicin, and etoposide and is alive and doing well more than 2 years after completion of her therapy, with no evidence of disease.
  
  
  CONCLUSIONS
  In young patients who desire future fertility, conservative surgery followed by aggressive multiagent chemotherapy may be an effective treatment regimen and warrants further consideration.
authors.affiliation: Department of Obstetrics and Gynecology, University of Chicago, Chicago, Illinois 60637, USA.
authors.forename: Sarosh
authors.initials: S
authors.lastname: Rana
authors.forename: Bretta K
authors.initials: BK
authors.lastname: Warren
authors.forename: S Diane
authors.initials: SD
authors.lastname: Yamada
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D018288:Carcinoma, Small Cell / Q000401:mortality / Q000628:therapy*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005187:Fallopian Tubes / Q000601:surgery*; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000401:mortality / Q000628:therapy*; D010052:Ovariectomy; D014747:Vinblastine / Q000008:administration & dosage
chemical_list: D001761:Bleomycin; D014747:Vinblastine; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D002945:Cisplatin