Decoding input signals in time domain--a model approach.
From an observation of efferent interspike intervals of a neuron, we consider how to decode the input temporal information. It is found that the integrate-and-fire model is blind in the temporal domain due to the fact that its efferent firing rate is independent of the input temporal frequency. The conclusion is then confirmed for the integrate-and-fire model with correlated inputs, with reversal potentials, with a nonlinear leakage and with a subthreshold oscillation. For the Hodgkin-Huxley model, however, in terms of efferent firing rates alone, it is possible to read out the input temporal information.
Feng
Jianfeng
J
COGS, University of Sussex, Brighton, BN1 9QH, UK. jianfeng@cogs.susx.ac.uk http://www.cogs.susx.ac.uk/users/jianfeng
Brown
David
D
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D019706:Excitatory Postsynaptic Potentials / Q000502:physiology; D006801:Humans; D008959:Models, Neurological; D009433:Neural Inhibition / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology*; D013995:Time