title: Zooxanthellamide B, a novel large polyhydroxy metabolite from a marine dinoflagellate of Symbiodinium sp.
abstract: Zooxanthellamide B, C(128)H(220)N(2)O(53)S(2), a polyhydroxy secondary metabolite, was isolated from a cultured marine dinoflagellate of the genus Symbiodinium. A detailed 2D NMR analysis revealed the chemical structure as a delta-lactone analogue of zooxanthellamide A, which had previously been isolated from the same dinoflagellate by us. The relative configuration of the delta-lactone moiety was determined by NOE experiments and a coupling constant analysis, and that of other ring systems was found to be the same as zooxanthellamide A by the chemical correlation between zooxanthellamides A and B.
authors.affiliation: Graduate School of Bioagricultural Sciences, Nagoya University, Japan.
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Onodera
authors.forename: Hideshi
authors.initials: H
authors.lastname: Nakamura
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Oba
authors.forename: Makoto
authors.initials: M
authors.lastname: Ojika
mesh_terms: D017666:Deuterium Oxide; D005057:Eukaryotic Cells / Q000737:chemistry* / Q000378:metabolism*; D005233:Fatty Alcohols / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism*; D007783:Lactones / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D005233:Fatty Alcohols; D006027:Glycosides; D007783:Lactones; C494873:zooxanthellamide B; D017666:Deuterium Oxide