Chemical imaging of biological systems with the scanning electrochemical microscope.
A brief overview on recent advances in the application of scanning electrochemical microscopy (SECM) to the investigation of biological systems is presented. Special emphasis is given to the mapping of local enzyme activity by SECM, which is exemplified by relevant original systems.
Gyurcsányi
Róbert E
RE
Institute of General and Analytical Chemistry, Budapest University of Technology and Economics, Szt. Gellért tér 4, Budapest, 1111-Hungary. robertgy@mail.bme.hu
Jágerszki
Gyula
G
Kiss
Gergely
G
Tóth
Klára
K
D000818:Animals; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods*; D004798:Enzymes / Q000032:analysis* / Q000378:metabolism*; D006801:Humans; D006824:Hybridization, Genetic / Q000502:physiology; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008839:Microelectrodes; D008853:Microscopy / Q000379:methods*; D025941:Protein Interaction Mapping / Q000379:methods*
D004798:Enzymes