title: Drastic differences in Crh and HPr synthesis levels reflect their different impacts on catabolite repression in Bacillus subtilis.
abstract: In Bacillus subtilis, carbon catabolite repression (CCR) of catabolic genes is mediated by ATP-dependent phosphorylation of HPr and Crh. Here we show that the different efficiencies with which these two proteins contribute to CCR may be due to the drastic differences in their synthesis rates under conditions that cause CCR.
authors.affiliation: Laboratoire de Chimie Bactérienne, UPR 9043, Institut de Biologie Structurale et Microbiologie-CNRS, 13009 Marseille, France.
authors.forename: Boris
authors.initials: B
authors.lastname: Görke
authors.forename: Laetitia
authors.initials: L
authors.lastname: Fraysse
authors.forename: Anne
authors.initials: A
authors.lastname: Galinier
mesh_terms: D001412:Bacillus subtilis / Q000378:metabolism*; D001426:Bacterial Proteins / Q000096:biosynthesis*; D002244:Carbon / Q000378:metabolism*; D010750:Phosphoproteins / Q000096:biosynthesis*; D014157:Transcription Factors / Q000096:biosynthesis*
chemical_list: D001426:Bacterial Proteins; C118042:Crh protein, Bacillus subtilis; D010750:Phosphoproteins; C442131:ScoC protein, Bacillus subtilis; D014157:Transcription Factors; D002244:Carbon