title: [A case of ovarian cancer stage IV and advanced rectal cancer responding to paclitaxel/carboplatin].
abstract: A 43-year-old woman who had ovarian cancer with massive ascites and pleural effusion as well as rectal cancer underwent probe laparotomy. However, only bilateral adnexectomy was performed since radical surgery was impossible due to severe carcinomatosa peritonitis. Three courses of chemotherapy with paclitaxel and carboplatin (T-J therapy) were carried out. Following chemotherapy, the ascites and pleural effusion had completely disappeared and the size of rectal cancer had shrunk as well. The chemotherapeutic effect was evaluated as a partial response in the rectal cancer. Therefore, as interval debulking surgery, abdominal total hysterectomy, omentectomy, low anterior resection pelvic lymphadenectomy were performed. Three further courses of chemotherapy were performed. There is no evidence of recurrence of ovarian cancer and rectal cancer 3 years after the first surgery.
authors.affiliation: Dept. of Obstetrics and Gynecology, Okanami General Hospital.
authors.forename: Ryuji
authors.initials: R
authors.lastname: Kawaguchi
authors.forename: Naoto
authors.initials: N
authors.lastname: Furukawa
authors.forename: Yuki
authors.initials: Y
authors.lastname: Morimoto
authors.forename: Masaki
authors.initials: M
authors.lastname: Ohi
authors.forename: Toru
authors.initials: T
authors.lastname: Osawa
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Koike
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Miyake
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016190:Carboplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D018284:Cystadenocarcinoma, Serous / Q000188:drug therapy* / Q000473:pathology; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008197:Lymph Node Excision; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy*; D009852:Omentum / Q000601:surgery; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D017239:Paclitaxel / Q000008:administration & dosage; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology
chemical_list: D016190:Carboplatin; D017239:Paclitaxel