title: Effect of medication in Parkinson's disease: a wavelet analysis of EMG signals.
abstract: The improvements in the motor ability in patients with Parkinson's disease due to antiparkinsonian medication is well-known and widely documented. Recent results, based both on kinematic parameters and standard electromyographic (EMG) signal analysis, clearly indicated that the medication reduced, as expected, the clinical signs of Parkinson's disease, but did not restore agonist burst duration modulation with distance in elbow flexion movements. The main aim of the present work is to shed more light on this medication effect using a wavelet analysis approach on multiple EMG signals recorded both on shoulder and elbow muscles in ballistic or rapid movements. The wavelet cross-correlation information allows us to evidence some important quantitative features of the EMG signals due to medication.
authors.affiliation: Department of Neuroscience, University of Pisa, Pisa, Italy.
authors.forename: Soo-Kyung
authors.initials: SK
authors.lastname: Strambi
authors.forename: Bruno
authors.initials: B
authors.lastname: Rossi
authors.forename: Gennaro
authors.initials: G
authors.lastname: De Michele
authors.forename: Stefano
authors.initials: S
authors.lastname: Sello
mesh_terms: D000368:Aged; D000465:Algorithms; D000978:Antiparkinson Agents / Q000627:therapeutic use*; D001132:Arm / Q000503:physiopathology; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004576:Electromyography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009068:Movement; D009119:Muscle Contraction; D018482:Muscle, Skeletal / Q000503:physiopathology; D010300:Parkinson Disease / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D020127:Recovery of Function / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D016896:Treatment Outcome
chemical_list: D000978:Antiparkinson Agents