title: Stereoselective synthesis of novel 4'-branched and bicyclo[3.1.0]hexane-templated nucleoside.
abstract: The racemic and stereoselective synthesis of a novel nucleoside 4'-branched and bicyclo[3.1.0]hexane templated nucleoside 15 was accomplished using a [3,3]-sigmatropic rearrangement, an intramolecular carbene cycloaddition reaction and a Curtius rearrangement as the key reactions.
authors.affiliation: College of Pharmacy, Chosun University, Kwangju, Republic of Korea. hongjh@mail.chosun.ac.kr
authors.forename: Joon Hee
authors.initials: JH
authors.lastname: Hong
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis; D000998:Antiviral Agents / Q000138:chemical synthesis; D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis*; D015195:Drug Design; D006586:Hexanes / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D009705:Nucleosides / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D000970:Antineoplastic Agents; D000998:Antiviral Agents; D001643:Bridged Bicyclo Compounds; D006586:Hexanes; D009705:Nucleosides; C026385:n-hexane