MAPPP: MHC class I antigenic peptide processing prediction.
MAPPP is a bioinformatics tool for the prediction of potential antigenic epitopes presented on the cell surface by major histocompatibility complex class I (MHC I) molecules to CD8 positive T lymphocytes. It combines existing predictions for proteasomal cleavage with peptide anchoring to MHC I molecules.
Hakenberg
Jörg
J
University of Ulm, Department of Theoretical Computer Science, Ulm, Germany.
Nussbaum
Alexander K
AK
Schild
Hansjörg
H
Rammensee
Hans-Georg
HG
Kuttler
Christina
C
Holzhütter
Hermann-Georg
HG
Kloetzel
Peter-M
PM
Kaufmann
Stefan H E
SH
Mollenkopf
Hans-Joachim
HJ
D000465:Algorithms; D017951:Antigen Presentation / Q000276:immunology; D003546:Cysteine Endopeptidases / Q000737:chemistry / Q000276:immunology; D003628:Database Management Systems; D018984:Epitopes, T-Lymphocyte / Q000737:chemistry* / Q000276:immunology*; D015395:Histocompatibility Antigens Class I / Q000032:analysis* / Q000737:chemistry*; D016247:Information Storage and Retrieval / Q000379:methods; D008956:Models, Chemical; D009097:Multienzyme Complexes / Q000737:chemistry / Q000276:immunology; D010455:Peptides / Q000737:chemistry / Q000276:immunology; D046988:Proteasome Endopeptidase Complex; D011485:Protein Binding; D025941:Protein Interaction Mapping / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software; D013329:Structure-Activity Relationship; D014584:User-Computer Interface
D018984:Epitopes, T-Lymphocyte; D015395:Histocompatibility Antigens Class I; D009097:Multienzyme Complexes; D010455:Peptides; D003546:Cysteine Endopeptidases; D046988:Proteasome Endopeptidase Complex