title: Dizziness.
abstract: BACKGROUND
  The article gives an overview of the most frequent forms of vertigo, that are of peripheral-labyrinthine, central-vestibular, psychogenic, or physiologic origin. Dizziness or vertigo is a result of a mismatch between 3 sensory systems: the vestibular, the visual, and the somatosensory systems. These systems are mutually interactive and redundant in that orientation and balance are guided by simultaneous reafferent cues. The functional ranges of the systems overlap, thus permitting them to compensate in part for each other's deficiencies.
  
  
  CONCLUSIONS
  Vertigo is not a well-defined disease entity, but rather a multisensory syndrome induced either by stimulation of the intact sensorimotor system by motion (eg, physiologic vertigo as in motion sickness or height vertigo), or by pathologic dysfunction of any of the stabilizing sensory systems (eg, peripheral vestibular as in vestibular neuritis, or central vestibular as in vertebro-basilar ischemia). The core region in vestibular vertigo syndromes is the vestibulo-ocular reflex, a 3-neuron arc that mediates the information of the semicircular canals and otoliths via the vestibular nerve and vestibular nucleus to the ocular motor nuclei (VI, IV, III) and the supranuclear integration centers in the ponto-mesencephalic brain stem.
  
  
  CONCLUSIONS
  Clinical phenomena characteristic for physiological and pathologic vertigo syndromes include postural, perceptual, oculomotor, and vegetative syndromes, which manifest with ataxia, nystagmus, vertigo, and nausea. Thus, the clinical testing must include examinations of postural, perceptual, oculomotor, and vegetative dysfunctions.
authors.affiliation: Department of Neurology, Johannes Gutenberg University, Mainz, Germany. dieterich@neurologie.klinik.uni-mainz.de
authors.forename: Marianne
authors.initials: M
authors.lastname: Dieterich
mesh_terms: D001259:Ataxia / Q000150:complications; D002561:Cerebrovascular Disorders / Q000150:complications; D003052:Cochlear Aqueduct; D015834:Cochlear Diseases / Q000150:complications; D005402:Fistula / Q000150:complications; D006801:Humans; D008575:Meniere Disease / Q000150:complications; D009041:Motion Sickness / Q000150:complications; D011187:Posture / Q000502:physiology; D014717:Vertigo / Q000209:etiology* / Q000503:physiopathology* / Q000628:therapy; D020338:Vestibular Neuronitis / Q000150:complications