[Studies on the extraction of ingredients from Chinese traditional medicine with CO2 supercritical fluid].
OBJECTIVE
To study the extraction technology with CO2 supercritical fluid in Chinese Traditional Medicine by extracting the anthraquinones ingredients from Salvia miltiorrhiza and Polygonum caspidatum.


METHODS
Extractions were made under different pressure, temperature, extraction time, entrainer, and the extracts were analyzied by TLC and HPLC.


RESULTS
The technology could be used in extraction and isolation. Under certain conditions, different contents of the extracts could be obtained.


CONCLUSIONS
CO2 supercritical fluid is good at extracing low polarity ingredients, and it shows the evident individurity in extraction of Chinese herb. The technological factors in industrial usage must be thought of all over.
Zhou
Jie-ming
JM
Guilin Sanjin Pharmaceutical CO., LTD, Guilin 541004, Guangxi, China.
Liang
Fang-lin
FL
Wu
Guang-xong
GX
Yan
Hai
H
D045784:Abietanes; D002245:Carbon Dioxide; D025924:Chromatography, Supercritical Fluid / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification*; D004642:Emodin / Q000031:analogs & derivatives* / Q000302:isolation & purification; D010616:Phenanthrenes / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry*; D028502:Polygonum / Q000737:chemistry; D011312:Pressure; D027561:Salvia miltiorrhiza / Q000737:chemistry; D013696:Temperature
D045784:Abietanes; D004365:Drugs, Chinese Herbal; D010616:Phenanthrenes; C021751:tanshinone; D002245:Carbon Dioxide; C008905:physcione; D004642:Emodin