title: Examination of serum total IgG1 concentration in atopic and non-atopic dogs.
abstract: In this study, serum immunoglobulin G1 (IgG1) concentrations were examined in atopic and non-atopic dogs receiving different levels of parasite control. Significantly lower serum total IgG1 concentrations were found in non-atopic dogs receiving stringent parasite control than in atopic dogs or non-atopic dogs receiving less stringent parasite control. Examination of serum total IgG1 concentrations of atopic dogs after six months of allergen specific immunotherapy (ASIT) showed a significant increase in serum total IgG1 concentrations. It is proposed that serum total IgG1 concentrations are affected by parasitism, atopic dermatitis and ASIT.
authors.affiliation: Department of Veterinary Pathology, University of Glasgow Veterinary School, Bearsden Road, Glasgow G61 1QH.
authors.forename: M A
authors.initials: MA
authors.lastname: Fraser
authors.forename: P E
authors.initials: PE
authors.lastname: McNeil
authors.forename: G
authors.initials: G
authors.lastname: Gettinby
mesh_terms: D000485:Allergens / Q000276:immunology; D000818:Animals; D016022:Case-Control Studies; D003876:Dermatitis, Atopic / Q000276:immunology / Q000662:veterinary*; D004283:Dog Diseases / Q000097:blood / Q000276:immunology*; D004285:Dogs; D007114:Immunization / Q000662:veterinary; D007074:Immunoglobulin G / Q000097:blood*; D010375:Pedigree
chemical_list: D000485:Allergens; D007074:Immunoglobulin G