title: Villoglandular papillary adenocarcinoma of the uterine cervix in a pregnant woman: a case report and review of literature.
abstract: Villoglandular papillary adenocarcinoma (VPA) of cervix is rare but a well recognized variant of cervical adenocarcinoma with favorable prognosis occurring in younger age group. A 28-year-old white woman, gravida 3, para 2 was admitted for abnormal vaginal bleeding, when she was pregnant at 8th weeks of gestation. Physical examination revealed about 2.5 cm polipoid lesion of the cervix protruding into vagina. Histopathological findings were consistent with cervical VPA. After termination of pregnancy, radical hysterectomy type III was performed. The patient underwent second, third and fourth laparotomies because of recurrent pelvic masses. At the end of five years follow-up period, she died because of the complication of recurrent tumor. VPA is not an innocent tumor, and can be complicated by recurrence and metastasis. More radical surgical and medical attempts should be planned.
authors.affiliation: Department of Obstetric and Gynecology, Gulhane Military Medical Academy, Ankara, Turkey. mdede@gata.edu.tr
authors.forename: Murat
authors.initials: M
authors.lastname: Dede
authors.forename: Güzin
authors.initials: G
authors.lastname: Deveci
authors.forename: M Salih
authors.initials: MS
authors.lastname: Deveci
authors.forename: Mufit Cemal
authors.initials: MC
authors.lastname: Yenen
authors.forename: Umit
authors.initials: U
authors.lastname: Goktolga
authors.forename: Saffet
authors.initials: S
authors.lastname: Dilek
authors.forename: Omer
authors.initials: O
authors.lastname: Gunhan
mesh_terms: D000032:Abortion, Therapeutic; D000231:Adenocarcinoma, Papillary / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D000328:Adult; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007044:Hysterectomy; D009364:Neoplasm Recurrence, Local; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000601:surgery; D002583:Uterine Cervical Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery