Duplicate genes increase gene expression diversity within and between species.
Using microarray gene expression data from several Drosophila species and strains, we show that duplicated genes, compared with single-copy genes, significantly increase gene expression diversity during development. We show further that duplicate genes tend to cause expression divergences between Drosophila species (or strains) to evolve faster than do single-copy genes. This conclusion is also supported by data from different yeast strains.
Gu
Zhenglong
Z
Department of Ecology & Evolution, University of Chicago, 1101 East 57th Street, Chicago, Illinois 60637, USA.
Rifkin
Scott A
SA
White
Kevin P
KP
Li
Wen-Hsiung
WH
D000818:Animals; D005075:Biological Evolution; D004330:Drosophila / Q000235:genetics / Q000254:growth & development; D004331:Drosophila melanogaster / Q000235:genetics / Q000254:growth & development; D020440:Gene Duplication; D015870:Gene Expression; D017344:Genes, Insect; D014644:Genetic Variation; D008675:Metamorphosis, Biological; D005810:Multigene Family; D012441:Saccharomyces cerevisiae / Q000235:genetics; D013045:Species Specificity