title: MAPPP: MHC class I antigenic peptide processing prediction.
abstract: MAPPP is a bioinformatics tool for the prediction of potential antigenic epitopes presented on the cell surface by major histocompatibility complex class I (MHC I) molecules to CD8 positive T lymphocytes. It combines existing predictions for proteasomal cleavage with peptide anchoring to MHC I molecules.
authors.affiliation: University of Ulm, Department of Theoretical Computer Science, Ulm, Germany.
authors.forename: Jörg
authors.initials: J
authors.lastname: Hakenberg
authors.forename: Alexander K
authors.initials: AK
authors.lastname: Nussbaum
authors.forename: Hansjörg
authors.initials: H
authors.lastname: Schild
authors.forename: Hans-Georg
authors.initials: HG
authors.lastname: Rammensee
authors.forename: Christina
authors.initials: C
authors.lastname: Kuttler
authors.forename: Hermann-Georg
authors.initials: HG
authors.lastname: Holzhütter
authors.forename: Peter-M
authors.initials: PM
authors.lastname: Kloetzel
authors.forename: Stefan H E
authors.initials: SH
authors.lastname: Kaufmann
authors.forename: Hans-Joachim
authors.initials: HJ
authors.lastname: Mollenkopf
mesh_terms: D000465:Algorithms; D017951:Antigen Presentation / Q000276:immunology; D003546:Cysteine Endopeptidases / Q000737:chemistry / Q000276:immunology; D003628:Database Management Systems; D018984:Epitopes, T-Lymphocyte / Q000737:chemistry* / Q000276:immunology*; D015395:Histocompatibility Antigens Class I / Q000032:analysis* / Q000737:chemistry*; D016247:Information Storage and Retrieval / Q000379:methods; D008956:Models, Chemical; D009097:Multienzyme Complexes / Q000737:chemistry / Q000276:immunology; D010455:Peptides / Q000737:chemistry / Q000276:immunology; D046988:Proteasome Endopeptidase Complex; D011485:Protein Binding; D025941:Protein Interaction Mapping / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software; D013329:Structure-Activity Relationship; D014584:User-Computer Interface
chemical_list: D018984:Epitopes, T-Lymphocyte; D015395:Histocompatibility Antigens Class I; D009097:Multienzyme Complexes; D010455:Peptides; D003546:Cysteine Endopeptidases; D046988:Proteasome Endopeptidase Complex