Clinical case of endocarditis due to Trichosporon inkin and antifungal susceptibility profile of the organism.
A fatal case of Trichosporon inkin prosthetic endocarditis is reported. The isolation sites and susceptibility profiles of 10 other isolates are also reviewed. Four strains were recovered from cutaneous or subcutaneous samples, four were recovered from urine, one was recovered from peritoneal liquid, and one was recovered from bone. Voriconazole and amphotericin B had the most potent activities in vitro against the isolates, with MIC geometric means of 0.11 and 0.30 microg/ml, respectively.
Ramos
Jose M
JM
Unidad de Enfermedades Infecciosas, Servicio de Medicina, Hospital General Universitario de Elche, Alicante, Spain.
Cuenca-Estrella
Manuel
M
Gutierrez
Felix
F
Elia
Matilde
M
Rodriguez-Tudela
Juan L
JL
D001021:Aortic Valve; D001705:Bioprosthesis / Q000009:adverse effects; D025141:Drug Resistance, Fungal; D004696:Endocarditis / Q000209:etiology* / Q000382:microbiology; D017809:Fatal Outcome; D006350:Heart Valve Prosthesis / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000209:etiology* / Q000382:microbiology; D014250:Trichosporon / Q000187:drug effects / Q000302:isolation & purification / Q000472:pathogenicity*