title: [Activation of G-proteins in three dimensions: one step toward the therapeutic inhibition of nucleotide exchange factors].
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Cherfils
authors.forename: Pierre
authors.initials: P
authors.lastname: Pacaud
mesh_terms: D000818:Animals; D020126:Brefeldin A / Q000494:pharmacology; D015195:Drug Design; D019204:GTP-Binding Proteins / Q000502:physiology*; D020662:Guanine Nucleotide Exchange Factors / Q000037:antagonists & inhibitors* / Q000502:physiology; D006153:Guanosine Diphosphate / Q000378:metabolism; D006160:Guanosine Triphosphate / Q000378:metabolism; D006801:Humans; D046911:Macromolecular Substances; D008954:Models, Biological; D008958:Models, Molecular; D011487:Protein Conformation; D015398:Signal Transduction / Q000502:physiology*; D013329:Structure-Activity Relationship
chemical_list: D020662:Guanine Nucleotide Exchange Factors; D046911:Macromolecular Substances; D006153:Guanosine Diphosphate; D020126:Brefeldin A; D006160:Guanosine Triphosphate; D019204:GTP-Binding Proteins