title: [Sjögren's syndrome with solitary nodular pulmonary amyloidosis].
abstract: We describe a case of limited pulmonary amyloidosis with Sjögren syndrome. A 58-yr-old woman was referred to our hospital because of an abnormal chest radiograph (solitary small nodule) that was examined to investigate the cause of a persistent cough. A chest CT revealed a solitary small nodule in the left lower lung field. The specimens obtained by thoracoscopic surgery showed AL (kappa) amyloid deposits with lymphoplasmacytic infiltrate. Immunofixation of the serum and concentrated urine failed to demonstrate monoclonal immunoglobulins, and no amyloid deposits in the stomach were detected. She was subsequently diagnosed as having primary Sjögren's syndrome. Nodular pulmonary amyloidosis with Sjögren syndrome is very rare condition, and most cases present multiple nodules. As far as is known, this is the first report of a solitary nodule in pulmonary amyloidosis with Sjögren syndrome.
authors.affiliation: Department of Respiratory Medicine, Ehime Prefectural Imabari Hospital, 4-5-5, Ishii-cho, Imabari, Ehime, 794-0006, Japan.
authors.forename: Kimiko
authors.initials: K
authors.lastname: Sakai
authors.forename: Yuji
authors.initials: Y
authors.lastname: Ohtsuki
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Hirasawa
authors.forename: Akihide
authors.initials: A
authors.lastname: Hashimoto
authors.forename: Kenji
authors.initials: K
authors.lastname: Nakamura
mesh_terms: D000686:Amyloidosis / Q000150:complications*; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000150:complications*; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000150:complications*