title: Autofluorescence as a novel approach to diagnosing macular holes.
abstract: OBJECTIVE
  To report the capability of autofluorescence as a novel approach to diagnosing macular holes.
  
  
  METHODS
  Observational case report.
  
  
  METHODS
  In an institutional study, autofluorescence photos and optical coherence tomography scans of two patients who had surgery for macular holes were reviewed.
  
  
  RESULTS
  Macular hole cases had a strong subfoveal autofluorescence signal, which disappeared after surgical closure of the macular hole.
  
  
  CONCLUSIONS
  Autofluorescence is a novel approach to demonstrating a macular hole. This technique can also be used to confirm postoperative outcome after macular hole repair. A lack of autofluorescence corresponds to macular hole closure.
authors.affiliation: Department of Ophthalmology, Denver Health Medical Center, University of Colorado, 777 Bannock Street, Mail Code 0156, Denver, CO 80204, USA. Antonio.ciardella@dhha.org
authors.forename: Antonio Pasquale
authors.initials: AP
authors.lastname: Ciardella
authors.forename: Grace C
authors.initials: GC
authors.lastname: Lee
authors.forename: Kevin
authors.initials: K
authors.lastname: Langton
authors.forename: Janet
authors.initials: J
authors.lastname: Sparrow
authors.forename: Stanley
authors.initials: S
authors.lastname: Chang
mesh_terms: D000368:Aged; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005453:Fluorescence; D006801:Humans; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000473:pathology* / Q000601:surgery; D012167:Retinal Perforations / Q000175:diagnosis* / Q000601:surgery; D041623:Tomography, Optical Coherence