title: Axonal regeneration of proctolinergic neurons in the central nervous system of the locust.
abstract: We provide evidence for axonal regeneration in the central nervous system (CNS) of the locust (Locusta migratoria). We followed the morphology of a small set of proctolin-immunoreactive neurons in the ventral nerve cord before and after crushing one cervical connective in the third instar. The proximal segments started sprouting within 3 days post lesion and grew into the suboesophageal ganglion within 9 days, covering a distance of approximately 2 mm. Within the suboesophageal ganglion, the regenerated neurites formed arborisations in the appropriate region which closely resemble the original shape. These findings will allow us to compare regeneration to the well-described embryonic development of axonal connectivity in this animal.
authors.affiliation: School of Veterinary Medicine Hannover, Cell Biology, Bischofsholer Damm 15, D-30173 Hannover, Germany.
authors.forename: Arne
authors.initials: A
authors.lastname: Pätschke
authors.forename: Gerd
authors.initials: G
authors.lastname: Bicker
authors.forename: Michael
authors.initials: M
authors.lastname: Stern
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000166:cytology / Q000502:physiology*; D003714:Denervation; D017952:Ganglia, Invertebrate / Q000166:cytology / Q000254:growth & development / Q000378:metabolism; D006110:Grasshoppers; D020439:Growth Cones / Q000378:metabolism / Q000502:physiology* / Q000648:ultrastructure; D007150:Immunohistochemistry; D009416:Nerve Regeneration / Q000502:physiology*; D009434:Neural Pathways / Q000166:cytology / Q000254:growth & development / Q000378:metabolism; D009479:Neuropeptides; D009842:Oligopeptides / Q000378:metabolism*
chemical_list: D009479:Neuropeptides; D009842:Oligopeptides; C011536:proctolin