title: Good outcome for infant of mother treated with chemotherapy for ewing sarcoma at 25 to 30 weeks' gestation.
abstract: There have been only three previous reports of women with Ewing sarcoma who received chemotherapy while pregnant. A 17-year-old woman with Ewing sarcoma was treated with a combination of doxorubicin (Adriamycin) and ifosfamide during the 25th to 30th week of gestation, and the baby was delivered at the 32nd week. The baby was developing normally at follow-up at 8 months of age. This case report supports the idea that in this situation, the pregnancy can be continued to await fetal growth, and second-trimester chemotherapy may not have a deleterious effect on the fetus.
authors.affiliation: Department of Pediatrics, Akita University School of Medicine, Akita, Japan. wako@ped.med.akita-u.ac.jp
authors.forename: Wako
authors.initials: W
authors.lastname: Nakajima
authors.forename: Akira
authors.initials: A
authors.lastname: Ishida
authors.forename: Maya
authors.initials: M
authors.lastname: Takahashi
authors.forename: Masashi
authors.initials: M
authors.lastname: Hirayama
authors.forename: Noriaki
authors.initials: N
authors.lastname: Washino
authors.forename: Masaki
authors.initials: M
authors.lastname: Ogawa
authors.forename: Shu
authors.initials: S
authors.lastname: Takahashi
authors.forename: Kyoji
authors.initials: K
authors.lastname: Okada
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D005865:Gestational Age; D006801:Humans; D007069:Ifosfamide / Q000627:therapeutic use; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy*; D012512:Sarcoma, Ewing / Q000175:diagnosis / Q000188:drug therapy* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D004317:Doxorubicin; D007069:Ifosfamide