title: Clinical case of endocarditis due to Trichosporon inkin and antifungal susceptibility profile of the organism.
abstract: A fatal case of Trichosporon inkin prosthetic endocarditis is reported. The isolation sites and susceptibility profiles of 10 other isolates are also reviewed. Four strains were recovered from cutaneous or subcutaneous samples, four were recovered from urine, one was recovered from peritoneal liquid, and one was recovered from bone. Voriconazole and amphotericin B had the most potent activities in vitro against the isolates, with MIC geometric means of 0.11 and 0.30 microg/ml, respectively.
authors.affiliation: Unidad de Enfermedades Infecciosas, Servicio de Medicina, Hospital General Universitario de Elche, Alicante, Spain.
authors.forename: Jose M
authors.initials: JM
authors.lastname: Ramos
authors.forename: Manuel
authors.initials: M
authors.lastname: Cuenca-Estrella
authors.forename: Felix
authors.initials: F
authors.lastname: Gutierrez
authors.forename: Matilde
authors.initials: M
authors.lastname: Elia
authors.forename: Juan L
authors.initials: JL
authors.lastname: Rodriguez-Tudela
mesh_terms: D001021:Aortic Valve; D001705:Bioprosthesis / Q000009:adverse effects; D025141:Drug Resistance, Fungal; D004696:Endocarditis / Q000209:etiology* / Q000382:microbiology; D017809:Fatal Outcome; D006350:Heart Valve Prosthesis / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000209:etiology* / Q000382:microbiology; D014250:Trichosporon / Q000187:drug effects / Q000302:isolation & purification / Q000472:pathogenicity*