title: Molecular fingerprinting of Mycobacterium bovis subsp. caprae isolates from central Europe.
abstract: To study the dissemination of Mycobacterium bovis subsp. caprae, 79 European isolates from cattle, humans, and other hosts were examined by spoligotyping and IS6110 restriction fragment length polymorphism (RFLP) analysis. Among a total of 11 different spoligotypes identified, type C1 proved to be predominant (n = 62). Five of the spoligotypes are described for the first time. A total of 43 different RFLP types were identified, thus allowing further differentiation for epidemiological tracking. Isolates from a series of outbreaks in one village proved to be of the same spoligotype and of identical or closely related RFLP types.
authors.affiliation: Federal Research Centre for Virus Diseases of Animals (BFAV), Jena, Germany.
authors.forename: Wilfried
authors.initials: W
authors.lastname: Erler
authors.forename: Gerald
authors.initials: G
authors.lastname: Martin
authors.forename: Konrad
authors.initials: K
authors.lastname: Sachse
authors.forename: Ludmila
authors.initials: L
authors.lastname: Naumann
authors.forename: Dagmar
authors.initials: D
authors.lastname: Kahlau
authors.forename: Jörg
authors.initials: J
authors.lastname: Beer
authors.forename: Milan
authors.initials: M
authors.lastname: Bartos
authors.forename: György
authors.initials: G
authors.lastname: Nagy
authors.forename: Zeljko
authors.initials: Z
authors.lastname: Cvetnic
authors.forename: Manca
authors.initials: M
authors.lastname: Zolnir-Dovc
authors.forename: Ivo
authors.initials: I
authors.lastname: Pavlik
mesh_terms: D000818:Animals; D002417:Cattle; D016172:DNA Fingerprinting; D005060:Europe; D019143:Evolution, Molecular; D006801:Humans; D017720:Molecular Epidemiology; D009163:Mycobacterium bovis / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D012150:Polymorphism, Restriction Fragment Length; D034421:Sus scrofa; D013553:Swine Diseases / Q000382:microbiology; D014376:Tuberculosis / Q000382:microbiology / Q000662:veterinary; D014380:Tuberculosis, Bovine / Q000382:microbiology