Separation of quaternary ammonium diastereomeric oligomers by capillary electrophoresis.
The separation of novel diastereomeric trimers (3M) and pentamers (5M), derived from quaternary ammonium salts, was studied in conventional, uncoated and coated capillaries using capillary zone electrophoresis (CZE) with a variety of buffers and additives. Resolution of 5M diastereomers was best achieved using gamma-cyclodextrin (gamma-CD) as a chiral selector, while no diastereomeric resolution was realized for the 3M material.
Zhang
Bin
B
Department of Chemistry, 102 Hurtig Hall, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Krull
Ira S
IS
Cohen
Aharon
A
Smisek
David L
DL
Kloss
Alla
A
Wang
Bing
B
Bourque
Andre J
AJ
D019075:Electrophoresis, Capillary / Q000379:methods*; D011108:Polymers / Q000737:chemistry*; D000644:Quaternary Ammonium Compounds / Q000302:isolation & purification*; D013237:Stereoisomerism
D011108:Polymers; D000644:Quaternary Ammonium Compounds