title: Distribution of Candida species among bloodstream isolates.
abstract: OBJECTIVE
  To identify the distribution of Candida species causing bloodstream infections.
  
  
  METHODS
  This study was conducted at the Armed Forces Hospital, Riyadh, Kingdom of Saudi Arabia. All cases of candidemia from the period 1996 through to 2002 were retrospectively identified through the records from the Department of Clinical Microbiology.
  
  
  RESULTS
  Two hundred and ninety-four candidemic episodes were identified, 176 (59.9%) occurred in the intensive care units (ICUs), 32 (10.9%) medical, 30 (10.2%) surgical wards, 24 (8%) from patients with hematologic malignancies and 15 (5%) from pediatric wards. Candida albicans (C. albicans) was the most frequently isolated species with 149 (50.7%) cases, followed by Candida tropicalis (C. tropicalis) 61 (20.7%), Candida parapsilosis 32 (10.9%), Candida krusei (C. krusei) 23 (7.8%) and Candida glabrata 21 (7.1%). Other species were not common. There is an increase in the proportion of non C. albicans species as the causative agents of candidemia. In certain clinical settings, non C. albicans species predominate as in the Adult General Intensive Care Unit with C. tropicalis as the most common. While in patients with hematologic malignancies, C. krusei species is the most common.
  
  
  CONCLUSIONS
  These findings reinforce the need for continued and active surveillance programs to address the changes in the species distribution among candidal bloodstream isolates which will help to develop effective, preventive and therapeutic strategies.
authors.affiliation: Department Microbiology, Armed Forces Hospital, Riyadh, Kingdom of Saudi Arabia. asjass2002@yahoo.com
authors.forename: Asma M
authors.initials: AM
authors.lastname: Al-Jasser
authors.forename: Noura A
authors.initials: NA
authors.lastname: Elkhizzi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002175:Candida / Q000145:classification / Q000302:isolation & purification*; D002176:Candida albicans / Q000302:isolation & purification; D002177:Candidiasis / Q000453:epidemiology / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D003430:Cross-Sectional Studies; D005260:Female; D016469:Fungemia / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D016533:Mycological Typing Techniques; D012529:Saudi Arabia / Q000453:epidemiology