title: Graves' disease associated with Klinefelter's syndrome.
abstract: Klinefelter's syndrome is one of the most common forms of primary hypogonadism and infertility in males. It is characterized by small and firm testes, gynecomastia, azoospermia, and an elevated gonadotropin level. The frequencies of diabetes mellitus, breast cancer, and germ cell neoplasia increases in Klinefelter's syndrome. We report upon a 35 year-old male patient with Graves' disease in association with Klinefelter's syndrome; as confirmed by chromosome analysis. The patient is being treated with antithyroid medication for Graves' disease and by testosterone replacement for Klinefelter's syndrome.
authors.affiliation: Department of Internal Medicine, Yongdong Severance Hospital, Yonsei University College of Medicine, 146-92 Dogok-dong, Kangnam-gu, Seoul 135-720, Korea.
authors.forename: Jong-Suk
authors.initials: JS
authors.lastname: Park
authors.forename: Chul-Sik
authors.initials: CS
authors.lastname: Kim
authors.forename: Joo-Young
authors.initials: JY
authors.lastname: Nam
authors.forename: Dol-Mi
authors.initials: DM
authors.lastname: Kim
authors.forename: Soo-Jee
authors.initials: SJ
authors.lastname: Yoon
authors.forename: Chul-Woo
authors.initials: CW
authors.lastname: Ahn
authors.forename: Bong-Soo
authors.initials: BS
authors.lastname: Cha
authors.forename: Sung-Kil
authors.initials: SK
authors.lastname: Lim
authors.forename: Kyung-Rae
authors.initials: KR
authors.lastname: Kim
authors.forename: Hyun-Chul
authors.initials: HC
authors.lastname: Lee
authors.forename: Kap-Bum
authors.initials: KB
authors.lastname: Huh
mesh_terms: D000328:Adult; D006111:Graves Disease / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D007006:Hypogonadism / Q000209:etiology* / Q000235:genetics / Q000473:pathology; D007713:Klinefelter Syndrome / Q000150:complications* / Q000235:genetics / Q000473:pathology; D008297:Male; D011877:Radionuclide Imaging