title: Non-ketotic hyperglycaemia presenting as epilepsia partialis continua.
abstract: Epilepsia partialis continua (EPC) is a rare epileptic syndrome, observed in various cortical lesions and also in metabolic disorders. We report the case of a 57-year-old patient with EPC as the first manifestation of hyperosmolar non-ketotic hyperglycaemia (NKH) of diabetes mellitus. Computed tomography (CT) and magnetic resonance imaging (MRI) were normal. Initial laboratory data revealing serum glucose 1540 mg/dl, and serum osmolality 391 mOsm/l confirmed the diagnosis. Electroencephalography (EEG) showed ictal discharges in the ipsilateral hemisphere during focal seizures. Seizures are resistant to anticonvulsant treatment and respond best to insulin and rehydration. Focal motor seizures or EPC are commonly a symptom of NKH in the elderly patients. We recommend that in such cases a metabolic disorder such as diabetes mellitus be ruled out.
authors.affiliation: Department of Neurology, Haseki Research and Educational Hospital, Istanbul, Turkey. ozlemcokar@hotmail.com
authors.forename: Ozlem
authors.initials: O
authors.lastname: Cokar
authors.forename: Betül
authors.initials: B
authors.lastname: Aydin
authors.forename: Feriha
authors.initials: F
authors.lastname: Ozer
mesh_terms: D003937:Diagnosis, Differential; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000175:diagnosis* / Q000378:metabolism*; D006801:Humans; D006943:Hyperglycemia / Q000378:metabolism*; D007657:Ketone Bodies / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index
chemical_list: D007657:Ketone Bodies