title: Parkinson disease of ranking lawyer and legislator SJV Chelvanayakam: a hypothesis.
abstract: SJV Chelvanayakam (1898-1977), a ranking civil lawyer and legislator, was probably the well known Parkinson disease victim in the 20th century Sri Lanka. He was born in Ipoh, Malaya, where his father had moved in the last decade of the 19th century for professional advancement. Ipoh was then an attractive location for migrants from China and the Indian subcontinent since it was in the Kinta valley--touted then, as the world's richest single tin field. Chelvanayakam was brought to Jaffna peninsula when he was aged four (in 1902 or 1903) by his mother, who returned to her native Tellipalai town partly due to indifferent health during her stay in Kinta region. In this communication, I present a hypothesis that organotin exposure as a foetus or during infancy at his place of birth is likely to have been a contributing factor to Chelvanayakam's Parkinsonism. It seems to fit the available circumstantial evidence.
authors.affiliation: Center for Human Evolutionary Modelling Research, Kyoto University-Primate Research Institute, Inuyama City, Aichi 484-8506, Japan. kantha@pri.kyoto-u.ac.jp
authors.forename: S J V
authors.initials: SJ
authors.lastname: Chelvanayakam
mesh_terms: D005197:Famous Persons; D049673:History, 20th Century; D006801:Humans; D007603:Jurisprudence; D013188:Sri Lanka