Invasive middle ear cholesterol granuloma involving the basal turn of the cochlea with profound sensorineural hearing loss.
METHODS
A retrospective surgical case review.


METHODS
A tertiary-care, university teaching hospital.


METHODS
The authors describe a unique case operated on for a middle ear cholesterol granuloma, which had invaded the cochlea and vestibule causing profound sensorineural deafness.


METHODS
Extended radical mastoidectomy and labyrinthectomy with musculofascial seal.


RESULTS
Successful postoperative outcome with no recurrence seen after 2 years of follow up.


CONCLUSIONS
To the authors' knowledge, this is the first reported case of a primary middle ear cholesterol granuloma with direct invasion into the cochlea. Such invasion of the otic capsule by cholesterol granulomas is rare and presents a diagnostic challenge to the attending otologist and radiologist. Salient points of the case history, pathogenesis, imaging studies, histopathology, and management are presented with a review of the current literature.
Murugasu
Euan
E
Tan Tock Seng Hospital, Singapore. emurugasu@ceistanford.com
Yong
Tan Tiong
TT
Yoon
Chong Pek
CP
D000328:Adult; D002784:Cholesterol; D003051:Cochlea / Q000473:pathology*; D004432:Ear, Middle / Q000473:pathology*; D015745:Granuloma, Foreign-Body / Q000150:complications / Q000601:surgery*; D006319:Hearing Loss, Sensorineural / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013506:Otologic Surgical Procedures; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014722:Vestibule, Labyrinth / Q000473:pathology
D002784:Cholesterol