title: [A study of lacunar folds in relation to the etiology and severity of dry eye].
abstract: OBJECTIVE
  To determine the diagnostic value of studying lacunar folds in relation to the different etiologies responsible for dry-eye syndrome.
  
  
  METHODS
  We present a prospective study of 206 eyes from 106 patients (38 males and 68 females). In all patients the abduction degree was measured after instilling a fluorescein drop, which makes lacunar folds disappear. We divided the patients into ten etiological groups applying Madrid classification criteria. Patients were also divided into four groups according to clinical severity.
  
  
  RESULTS
  We found the early disappearance of lacunar folds was more prevalent among patients with immunological dry eye. Early disappearance was less frequent in patients with tantalic, pharmacological, inflammatory and traumatic dry eye. The folds disappeared more rapidly in patients with greater clinical severity.
  
  
  CONCLUSIONS
  The early disappearance of lacunar folds is a sign of conjunctival retraction manifest in patients with dry eye syndrome. The degree of conjunctival retraction degree varies according to the dry eye etiology and severity of the symptoms.
authors.affiliation: Servicio de Oftalmología, Hospital General Cruz Roja, Madrid, España.
authors.forename: J S
authors.initials: JS
authors.lastname: López García
authors.forename: I
authors.initials: I
authors.lastname: García Lozano
authors.forename: J
authors.initials: J
authors.lastname: Martínez Garchitorena
mesh_terms: D003228:Conjunctiva / Q000473:pathology*; D003229:Conjunctival Diseases / Q000175:diagnosis*; D003287:Contrast Media; D003941:Diagnostic Techniques, Ophthalmological; D015352:Dry Eye Syndromes / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D019793:Fluorescein; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012720:Severity of Illness Index
chemical_list: D003287:Contrast Media; D019793:Fluorescein