title: Influences of traditional Chinese medicine on non-specific immunity of Jian Carp (Cyprinus carpio var. Jian).
abstract: The influence of traditional Chinese medicine (TCM) formulation from Astragalus Root (Radix astragalin seu Hedysari) and Chinese Angelica Root (R. Angelicae Sinensis) at a ratio of 5:1 (w/w) on non-specific immunity of Jian carp, Cyprinus carpio var. Jian was investigated. The number of NBT-positive cells in the blood and lysozyme and complement activities in the serum of Carp fed with commercial feed supplemented with 1.0% (diet 1) and 1.5% (diet 2) TCM at 10 day of post-feeding were not different from those of the control group fed with feed unsupplemented TCM 10 days post-feeding (P>0.05), but at 20 and 30 days they increased significantly (P<0.05). The values of diet 1 group and diet 2 group at 20 day and at 30 day were not significantly different (P>0.05) from each other. In addition, the TCM formula increased body weight of experimental fish by about 16.84% (diet 1) and 19% (diet 2) above that of the control group. Therefore, these data suggest that the TCM formula could elevate the function of non-specific immunity of Jian carp. The optimal dosage added to commercial carp feed was 1.0% (w/w) and the oral administration time as a course of treatment was 20 days.
authors.affiliation: Fisheries College of Zhanjiang University, Xiashan District, Zhanjiang City, Guangdong 524025, China. jianjichang@21cn.com
authors.forename: Jichang
authors.initials: J
authors.lastname: Jian
authors.forename: Zaohe
authors.initials: Z
authors.lastname: Wu
mesh_terms: D029971:Angelica sinensis; D000818:Animals; D027885:Astragalus propinquus; D001835:Body Weight; D002347:Carps / Q000276:immunology*; D015941:Complement Hemolytic Activity Assay; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D007113:Immunity, Innate / Q000187:drug effects*; D008516:Medicine, Chinese Traditional; D009113:Muramidase / Q000187:drug effects / Q000276:immunology; D009580:Nitroblue Tetrazolium / Q000378:metabolism
chemical_list: D004365:Drugs, Chinese Herbal; D009580:Nitroblue Tetrazolium; C027492:Huang Qi; C044613:angelicae sinensis extract; D009113:Muramidase