title: Serologic responses to eastern and western equine encephalomyelitis vaccination in previously vaccinated horses.
abstract: A prospective study was performed to determine the serologic response of previously vaccinated horses to revaccination against eastern and western equine encephalomyelitis (EEE and WEE). Horses responded variably to each antigen, and some horses had low or undetectable antibodies 6 months after vaccination. Some horses did not develop increasing titers to EEE or WEE despite recent vaccination. Geometric mean titers peaked 2 weeks after revaccination and were significantly increased from before revaccination. Except for one horse, EEE:WEE titer ratios ranged from 0.25 to 2.0. Regular vaccination against EEE and WEE did not interfere with testing for Saint Louis encephalitis.
authors.affiliation: Department of Clinical Sciences, School of Veterinary Medicine, Tuskegee, AL 36088, USA.
authors.forename: Bryan M
authors.initials: BM
authors.lastname: Waldridge
authors.forename: James G W
authors.initials: JG
authors.lastname: Wenzel
authors.forename: A C
authors.initials: AC
authors.lastname: Ellis
authors.forename: Sarah E
authors.initials: SE
authors.lastname: Rowe-Morton
authors.forename: E Ricardo
authors.initials: ER
authors.lastname: Bridges
authors.forename: George
authors.initials: G
authors.lastname: D'Andrea
authors.forename: Rennia
authors.initials: R
authors.lastname: Wint
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D004663:Encephalitis Virus, Eastern Equine / Q000276:immunology*; D004667:Encephalitis Virus, Western Equine / Q000276:immunology*; D020242:Encephalomyelitis, Eastern Equine / Q000276:immunology / Q000662:veterinary*; D020241:Encephalomyelitis, Western Equine / Q000276:immunology / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases / Q000276:immunology*; D006736:Horses; D011446:Prospective Studies; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines