Antibody-catalyzed aminolysis of a chloropyrimidine derivative.
We have generated antibody FTB8E9 by immunization with the designed hapten to catalyze the aminolysis reaction of a chloropyrimidine derivative.
Tanaka
Fujie
F
The Skaggs Institute for Chemical Biology and the Departments of Chemistry and Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA. ftanaka@scripps.edu
Flores
Fabiola
F
Kubitz
Diane
D
Lerner
Richard A
RA
Barbas
Carlos F
CF
D000906:Antibodies / Q000737:chemistry / Q000378:metabolism*; D002384:Catalysis; D011743:Pyrimidines / Q000737:chemistry / Q000378:metabolism*
D000906:Antibodies; D011743:Pyrimidines