title: Unraveling the pathway of lipoic acid biosynthesis.
abstract: Lipoic acid is almost universally required for aerobic metabolism. However, the mechanism for its synthesis and incorporation into proteins has remained elusive. A groundbreaking study published in the December issue of Chemistry & Biology uncovers critical features of the lipoic acid biosynthetic pathway.
authors.affiliation: Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park 16802, USA.
authors.forename: Squire J
authors.initials: SJ
authors.lastname: Booker
mesh_terms: D002384:Catalysis; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics; D008063:Thioctic Acid / Q000096:biosynthesis* / Q000378:metabolism
chemical_list: D008063:Thioctic Acid