title: Topical prostaglandin F(2alpha) analog induced poliosis.
abstract: OBJECTIVE
  To report poliosis as a side effect associated with topical prostaglandin F(2alpha) (PGF(2alpha)) analogs.
  
  
  METHODS
  Case series.
  
  
  RESULTS
  Seven patients treated with different topical PGF(2alpha) analogs for primary open angle glaucoma developed bilateral poliosis, either alone or in combination with other adverse effects of PGF(2alpha) analog therapy.
  
  
  CONCLUSIONS
  Poliosis is a possible adverse effect of topical PGF(2alpha) analog therapy which is previously unreported. Topical PGF(2alpha) analog therapy should be included in the differential diagnosis of patients with poliosis.
authors.affiliation: Department of Ophthalmology, Flinders Medical Centre, Bedford Drive, Bedford Park, Adelaide, SA 5042, Australia.
authors.forename: Celia S
authors.initials: CS
authors.lastname: Chen
authors.forename: Jane
authors.initials: J
authors.lastname: Wells
authors.forename: Jamie E
authors.initials: JE
authors.lastname: Craig
mesh_terms: D000287:Administration, Topical; D000368:Aged; D000369:Aged, 80 and over; D000577:Amides; D000959:Antihypertensive Agents / Q000009:adverse effects*; D000069580:Bimatoprost; D003008:Cloprostenol / Q000009:adverse effects* / Q000031:analogs & derivatives*; D005140:Eyelashes / Q000187:drug effects*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000188:drug therapy; D006201:Hair Diseases / Q000139:chemically induced*; D006801:Humans; D006983:Hypertrichosis / Q000139:chemically induced; D007429:Intraocular Pressure / Q000187:drug effects; D000077338:Latanoprost; D008055:Lipids / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010859:Pigmentation Disorders / Q000139:chemically induced*; D011461:Prostaglandins F, Synthetic / Q000009:adverse effects*; D000069557:Travoprost
chemical_list: D000577:Amides; D000959:Antihypertensive Agents; D008055:Lipids; D011461:Prostaglandins F, Synthetic; D003008:Cloprostenol; D000077338:Latanoprost; D000069580:Bimatoprost; D000069557:Travoprost