Carcinoma arising in the pleural cavity following pneumonectomy for hydatid disease.
We report a case of carcinoma following 42 years of chronic empyema in a patient who underwent surgery for a hydatid cyst at the age of 3. At the time of diagnosis, an esophageal fistula was observed and treated with cyanoacrylate. We hypothesize that chronic inflammation of the pleura, caused by decades of empyema, associated with the presence of heterotopic squamous epithelium due to a long-standing esophago-pleural fistula, led to neoplastic transformation.
Zapatero Gaviria
J
J
Department of Thoracic Surgery, Fundación Jiménez Díaz, Hospital Ramón y Cajal, Madrid, Spain. zapatero89@hotmail.com
Garcia Franco
C E
CE
Jimenez Hiscock
L
L
Peñalver Pascual
R
R
Fogué Calv O
L
L
Muguruza Trueba
I
I
Lago Viguera
J
J
D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D002908:Chronic Disease; D003487:Cyanoacrylates / Q000627:therapeutic use; D004445:Echinococcosis, Pulmonary / Q000150:complications* / Q000601:surgery; D004653:Empyema / Q000209:etiology* / Q000601:surgery; D004937:Esophageal Fistula / Q000188:drug therapy / Q000209:etiology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000209:etiology*; D011013:Pneumonectomy / Q000009:adverse effects; D012086:Reoperation; D013997:Time Factors; D014014:Tissue Adhesives / Q000627:therapeutic use
D003487:Cyanoacrylates; D014014:Tissue Adhesives