title: [Indications for use of MTA, a review. Part 1: Chemical, physical and biological properties of MTA].
abstract: Mineral trioxide aggregate is a recently introduced dental material. It may be used to seal perforations, make retrograde fillings in root-end resections, seal open apices, or cap vital pulps. In this review of the literature, physical, chemical, and biologic properties of MTA are discussed. Studies have suggested that MTA provides a better seal than formerly used materials such as IRM, amalgam, and Super-EBA. Further, MTA has low cytotoxicity and excellent biocompatibility. In vivo studies demonstrated a beneficial effect of MTA on pulpal and periodontal regeneration. Although controlled randomized clinical trials are still missing, MTA appears to be a suitable material to tightly seal dental hard tissues from the periodontium, or to cap the exposed pulp.
authors.affiliation: Station für Endodontie, Klinik für Präventivzahnmedizin, Parodontologie und Kariologie, Zahnmedizinisches Zentrum der Universität Zürich. kathrin.schoenenberger@zzmk.unizh.ch
authors.forename: Kathrin Schönenberger
authors.initials: KS
authors.lastname: Göhring
authors.forename: Birgit
authors.initials: B
authors.lastname: Lehnert
authors.forename: Matthias
authors.initials: M
authors.lastname: Zehnder
mesh_terms: D017607:Aluminum Compounds / Q000737:chemistry / Q000633:toxicity; D000818:Animals; D000891:Anti-Infective Agents, Local / Q000737:chemistry / Q000633:toxicity; D001672:Biocompatible Materials / Q000737:chemistry / Q000633:toxicity; D017610:Calcium Compounds / Q000737:chemistry / Q000633:toxicity; D004338:Drug Combinations; D006801:Humans; D008422:Materials Testing; D010087:Oxides / Q000737:chemistry / Q000633:toxicity; D012184:Retrograde Obturation; D012387:Root Canal Filling Materials / Q000737:chemistry / Q000633:toxicity; D017640:Silicates / Q000737:chemistry / Q000633:toxicity; D018677:Tooth Injuries / Q000628:therapy; D014783:Viscosity
chemical_list: D017607:Aluminum Compounds; D000891:Anti-Infective Agents, Local; D001672:Biocompatible Materials; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate