title: Separation of quaternary ammonium diastereomeric oligomers by capillary electrophoresis.
abstract: The separation of novel diastereomeric trimers (3M) and pentamers (5M), derived from quaternary ammonium salts, was studied in conventional, uncoated and coated capillaries using capillary zone electrophoresis (CZE) with a variety of buffers and additives. Resolution of 5M diastereomers was best achieved using gamma-cyclodextrin (gamma-CD) as a chiral selector, while no diastereomeric resolution was realized for the 3M material.
authors.affiliation: Department of Chemistry, 102 Hurtig Hall, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
authors.forename: Bin
authors.initials: B
authors.lastname: Zhang
authors.forename: Ira S
authors.initials: IS
authors.lastname: Krull
authors.forename: Aharon
authors.initials: A
authors.lastname: Cohen
authors.forename: David L
authors.initials: DL
authors.lastname: Smisek
authors.forename: Alla
authors.initials: A
authors.lastname: Kloss
authors.forename: Bing
authors.initials: B
authors.lastname: Wang
authors.forename: Andre J
authors.initials: AJ
authors.lastname: Bourque
mesh_terms: D019075:Electrophoresis, Capillary / Q000379:methods*; D011108:Polymers / Q000737:chemistry*; D000644:Quaternary Ammonium Compounds / Q000302:isolation & purification*; D013237:Stereoisomerism
chemical_list: D011108:Polymers; D000644:Quaternary Ammonium Compounds