The myelinated axon is dependent on the myelinating cell for support and maintenance: molecules involved.
The myelin-forming cells, oligodendrocytes and Schwann cells, extend processes that spirally wrap axons and provide the insulation that allows rapid saltatory conduction. Recent data suggest a further role for the myelin-forming cells in axonal support and maintenance. This Mini-Review summarises some of the data that support this view and highlights the molecules involved.
Edgar
J M
JM
Applied Neurobiology Group, Institute of Comparative Medicine, University of Glasgow, Bearsden, Glasgow, Scotland. je22r@udcf.gla.ac.uk
Garbern
J
J
D000818:Animals; D001369:Axons / Q000502:physiology*; D003711:Demyelinating Diseases / Q000503:physiopathology; D006801:Humans; D009185:Myelin Proteins / Q000502:physiology; D009413:Nerve Fibers, Myelinated / Q000502:physiology*; D009836:Oligodendroglia / Q000502:physiology*; D021381:Protein Transport; D012583:Schwann Cells / Q000502:physiology*
D009185:Myelin Proteins