Detection of a novel HLA-A allele by polymerase chain reaction-sequence-specific oligonucleotide typing: HLA-A*0252.
Anew human leukocyte antigen (HLA) class I allele, HLA-A*0252, has been found during routine typing of samples for the Australian Bone Marrow Donor Registry. A*0252 differs from A*020101 at four codon positions, with all the new polymorphisms resulting in an amino acid change. The amino acids involved are located in the antigen-binding region of the HLA protein.
Hersee
J
J
Molecular Genetics, Tissue Typing, Australian Red Cross Blood Service, Sydney, NSW, Australia.
Dodd
R
R
Greville
W D
WD
Chapman
G
G
Taverniti
A
A
Le
T
T
Wallace
R
R
Kennedy
A
A
Dunckley
H
H
D001483:Base Sequence; D005091:Exons; D015234:HLA-A Antigens / Q000235:genetics*; D015789:HLA-A2 Antigen; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction
D015234:HLA-A Antigens; C495069:HLA-A*02:52 antigen; D015789:HLA-A2 Antigen