title: Management of invasive aspergillosis in high-risk patients.
abstract: Invasive aspergillosis can be difficult to diagnose and control, and conventional drug treatment is often highly toxic, producing medical complications that further compromise patients' health status and escalate health care costs. This article describes the clinical manifestations of Aspergillus infection and discusses approaches to its therapy, including newer pharmaceutical agents with fewer adverse effects, which offer the potential to improve outcomes and substantially lower the cost of treating aspergillosis.
authors.affiliation: Division of Nephrology and Hypertension, Oregon Health and Science University, Portland, USA.
authors.forename: Ali J
authors.initials: AJ
authors.lastname: Olyaei
mesh_terms: D000935:Antifungal Agents / Q000191:economics / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000191:economics; D001232:Aspergillus fumigatus / Q000302:isolation & purification; D017281:Cost of Illness; D004502:Education, Medical, Continuing; D006801:Humans; D008172:Lung Diseases, Fungal / Q000175:diagnosis* / Q000188:drug therapy* / Q000191:economics; D016896:Treatment Outcome; D014481:United States
chemical_list: D000935:Antifungal Agents