Sulfonium ylide epoxidation reactions: methylene transfer.
Using a D-mannitol derived chiral sulfide, terminal epoxides are formed in up to 76% ee; the first example of double asymmetric induction in a sulfonium methylide epoxidation is reported and an improved method of generating sulfonium ylides is detailed.
Bellenie
Benjamin R
BR
Unilever Centre for Molecular Science Informatics, Department of Chemistry, Lensfield Road, Cambridge, UK CB2 1EW.
Goodman
Jonathan M
JM