Multi-electrode recording from the developing visual pathway of awake behaving ferrets.
We have developed an effective technique for obtaining multi-electrode extracellular recordings from developing lateral geniculate nucleus (LGN) and visual cortex in awake behaving ferrets. Using this approach, we have been studying changes in the spatio-temporal patterns of spontaneous activity within the visual pathway during pre eye-opening development. In this paper, we describe the fabrication and implantation of 8- and 16-channel drivable multi-electrode arrays, which enable us to obtain high-quality multi-unit recordings from nearly 100% of our recording sites.
Chiu
Chiayu
C
Interdepartmental Program in Neuroscience, University of Rochester, Rochester, NY 14627, USA.
Weliky
Michael
M
D000818:Animals; D000831:Animals, Newborn; D001522:Behavior, Animal / Q000502:physiology; D004567:Electrodes, Implanted; D005289:Ferrets / Q000502:physiology*; D008297:Male; D014793:Visual Cortex / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology*; D014851:Wakefulness / Q000502:physiology*