Meta-analysis of BACTEC MGIT 960 and BACTEC 460 TB, with or without solid media, for detection of mycobacteria.
In a meta-analysis of 10 studies, the BACTEC 960/MGIT and BACTEC 460 systems showed a sensitivity and specificity in detecting mycobacteria (1,381 strains from 14,745 clinical specimens) of 81.5 and 99.6% and 85.8 and 99.9%, respectively. Combined with solid media, the sensitivity of the two systems increased to 87.7 and 89.7%, respectively.
Cruciani
M
M
HIV Outpatient Clinic, Center of Preventive Medicine, Verona, Italy. crucianimario@virgilio.it
Scarparo
C
C
Malena
M
M
Bosco
O
O
Serpelloni
G
G
Mengoli
C
C
D001431:Bacteriological Techniques / Q000706:statistics & numerical data; D003470:Culture Media; D006801:Humans; D009161:Mycobacterium / Q000145:classification / Q000302:isolation & purification*; D009164:Mycobacterium Infections / Q000175:diagnosis; D012680:Sensitivity and Specificity; D013045:Species Specificity
D003470:Culture Media