Postoperative nausea and vomiting in the plastic surgery patient.
Despite great advances in modern medicine, postoperative nausea and vomiting (PONV) continue to be a significant problem without a definitive cure. This article describes a prospective study conducted with 143 plastic surgery patients at a single institution between 1998 and 2000 to identify preoperative risk factors for PONV that may be specific to plastic surgery patients. In addition, a prophylactic regimen was identified that demonstrated a decrease in the incidence of PONV from the published incidence of 22% to 3%. The regimen includes the use of multiple antiemetic agents including ondansetron (Zofran) promethazine (Phenergan), and metoclopramide (Reglan), with the addition of dexamethasone (Decadron) in selected cases
Steely
Robert Lee
RL
Houston, TX 77002, USA.
Collins
Donald R
DR
Cohen
Benjamin E
BE
Bass
Kim
K
D000556:Ambulatory Surgical Procedures / Q000009:adverse effects; D000932:Antiemetics / Q000627:therapeutic use*; D003907:Dexamethasone / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008787:Metoclopramide / Q000627:therapeutic use; D017294:Ondansetron / Q000627:therapeutic use; D020250:Postoperative Nausea and Vomiting / Q000453:epidemiology / Q000517:prevention & control*; D011292:Premedication / Q000706:statistics & numerical data*; D011398:Promethazine / Q000627:therapeutic use; D011446:Prospective Studies; D019651:Plastic Surgery Procedures / Q000009:adverse effects* / Q000706:statistics & numerical data; D013997:Time Factors; D016896:Treatment Outcome
D000932:Antiemetics; D017294:Ondansetron; D003907:Dexamethasone; D011398:Promethazine; D008787:Metoclopramide