Cyclin C makes an entry into the cell cycle.
From yeast to humans, cell cycle progression is orchestrated by the oscillation of kinase activities associated with cyclins. In an article published recently in Cell, Ren and Rollins investigate mechanisms controlling the G0/G1 transition in quiescent cells and identify new cyclin C/Cdk3 complexes as key regulators of cell cycle reentry in human cells.
Sage
Julien
J
Departments of Pediatrics and Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.
D000818:Animals; D002453:Cell Cycle / Q000235:genetics*; D056745:Cyclin C; D056849:Cyclin-Dependent Kinase 3; D018844:Cyclin-Dependent Kinases / Q000378:metabolism*; D016213:Cyclins / Q000378:metabolism*; D016193:G1 Phase / Q000235:genetics; D006801:Humans; D016192:Resting Phase, Cell Cycle / Q000235:genetics; D016160:Retinoblastoma Protein / Q000378:metabolism
C503674:CCNC protein, human; D056745:Cyclin C; D016213:Cyclins; D016160:Retinoblastoma Protein; C098776:CDK3 protein, human; D056849:Cyclin-Dependent Kinase 3; D018844:Cyclin-Dependent Kinases