Application of selected reaction monitoring tandem mass spectrometry to the quantitative determination of an arsenic-containing nucleoside in a crude biological extract.
HPLC electrospray selected reaction monitoring tandem mass spectrometry was used for the determination of a key arsenic metabolite, 5'-dimethylarsinoyladenosine, at trace levels (ca. 20 microg As l(-1)) in a crude extract of kidney from the clam Tridacna derasa.
Francesconi
Kevin A
KA
University of Crete, Department of Chemistry, Environmental Chemical Processes Laboratory, Heraklion, Greece. spergantis@chemistry.uoc.gr
Pergantis
Spiros A
SA
D000241:Adenosine / Q000031:analogs & derivatives / Q000032:analysis; D000818:Animals; D001151:Arsenic / Q000032:analysis*; D001152:Arsenicals / Q000032:analysis; D049872:Bivalvia / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004784:Environmental Monitoring / Q000379:methods; D007668:Kidney / Q000737:chemistry*; D012758:Shellfish / Q000032:analysis*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods
C490151:5'-dimethylarsinoyladenosine; D001152:Arsenicals; D000241:Adenosine; D001151:Arsenic