title: Antioxidant enzyme levels in the erythrocytes of riboflavin-deficient and Trichinella spiralis-infected rats.
abstract: The erythrocyte antioxidant enzyme levels of catalase, superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) of riboflavin-deficient and Trichinella spiralis-infected rats were investigated. The rats were deprived of riboflavin at the 8th week of the experiment. At that time, the erythrocyte glutathione reductase activity coefficient (EGR AC), as an indicator of riboflavin status, was > or = 1.30 in rats fed a riboflavin-deficient diet and T. spiralis-infected rats fed a riboflavin-deficient diet showed no biochemical sign of riboflavin deficiency. At the 12th week of the experiment, the levels of catalase, SOD and GSH-Px were significantly lower in the riboflavin-deficient, T. spiralis-infected, and combined riboflavin-deficient and T. spiralis-infected, rats, compared to the control group. This may have been due to an increase in free oxygen radicals caused by riboflavin deficiency and parasitic infection.
authors.affiliation: Department of Tropical Nutrition and Food Science, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Panas
authors.initials: P
authors.lastname: Tumkiratiwong
authors.forename: Rungsunn
authors.initials: R
authors.lastname: Tungtrongchitr
authors.forename: Panata
authors.initials: P
authors.lastname: Migasena
authors.forename: Praneet
authors.initials: P
authors.lastname: Pongpaew
authors.forename: Wichit
authors.initials: W
authors.lastname: Rojekittikhun
authors.forename: Niyomsri
authors.initials: N
authors.lastname: Vudhivai
authors.forename: Anchalee
authors.initials: A
authors.lastname: Tungtrongchitr
authors.forename: Benjaluck
authors.initials: B
authors.lastname: Phonrat
authors.forename: Supaporn
authors.initials: S
authors.lastname: Nuamtanong
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D002374:Catalase / Q000097:blood*; D004198:Disease Susceptibility / Q000201:enzymology; D005979:Glutathione Peroxidase / Q000097:blood*; D051381:Rats; D017208:Rats, Wistar; D012257:Riboflavin Deficiency / Q000150:complications / Q000201:enzymology*; D018709:Statistics, Nonparametric; D013482:Superoxide Dismutase / Q000097:blood*; D017160:Trichinella spiralis; D014235:Trichinellosis / Q000150:complications / Q000201:enzymology*
chemical_list: D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase