SPR for molecular interaction analysis: a review of emerging application areas.
PubMed searches identified four emerging application areas for surface plasmon resonance systems. Food analysis, proteomics, immunogenicity and drug discovery. These application areas are reviewed. In connection with the review of drug discovery applications a case study is presented. This study demonstrates the value of combining results from drug-target and ADME predictive assays for compound selection.
Karlsson
Robert
R
Biacore AB, Rapsgatan 7, SE 754 50 Uppsala, Sweden. robert.karlsson@biacore.com
D000941:Antigens / Q000276:immunology; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005504:Food Analysis / Q000379:methods; D006801:Humans; D040901:Proteomics / Q000379:methods; D020349:Surface Plasmon Resonance / Q000379:methods / Q000639:trends*
D000941:Antigens