title: Aqueous liquid scintillation counting with fluor-containing nanosuspensions.
abstract: A microemulsion comprised of water, Brij 78, pentanol and styrene into which PPO and bis-MSB had been dissolved was prepared. Polymerization of the styrene resulted in a suspension of fluor-containing polystyrene nanoparticles (<100 nm). After a concentration step, the aqueous nanosuspension was able to detect (14)C with counting efficiencies over 50% of those of a commercially available scintillation cocktail. Monte Carlo calculations demonstrated that the size and concentration of the nanoparticles were appropriate for optimum detection efficiency.
authors.affiliation: Division of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536-0082, USA.
authors.forename: James C
authors.initials: JC
authors.lastname: Weekley
authors.forename: Sara
authors.initials: S
authors.lastname: Wuenschel
authors.forename: Paul E
authors.initials: PE
authors.lastname: Rosenstiel
authors.forename: Russell J
authors.initials: RJ
authors.lastname: Mumper
authors.forename: Michael
authors.initials: M
authors.lastname: Jay
mesh_terms: D002250:Carbon Radioisotopes / Q000032:analysis*; D004655:Emulsions; D007202:Indicators and Reagents; D011868:Radioisotopes / Q000032:analysis*; D012588:Scintillation Counting / Q000379:methods*; D013501:Surface-Active Agents; D014867:Water / Q000032:analysis*
chemical_list: D002250:Carbon Radioisotopes; D004655:Emulsions; D007202:Indicators and Reagents; D011868:Radioisotopes; D013501:Surface-Active Agents; D014867:Water