title: A phage protein confers resistance to the lactococcal abortive infection mechanism AbiP.
abstract: Phage bIL66M1 is sensitive to the lactococcal abortive infection mechanism AbiP. No spontaneous AbiP-resistant variant could be obtained at a frequency of <10(-10). However, AbiP-resistant variants were readily obtained during infection with both bIL66M1 and the highly homologous AbiP-resistant phage bIL170. Gain of AbiP resistance was due to the acquisition of the e6 gene from bIL170.
authors.affiliation: Laboratoire de Génétique Microbienne, INRA, 78352 Jouy-en-Josas, France.
authors.forename: Susana
authors.initials: S
authors.lastname: Domingues
authors.forename: Alain
authors.initials: A
authors.lastname: Chopin
authors.forename: S Dusko
authors.initials: SD
authors.lastname: Ehrlich
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Chopin
mesh_terms: D001426:Bacterial Proteins / Q000502:physiology*; D001435:Bacteriophages / Q000737:chemistry / Q000235:genetics / Q000254:growth & development*; D001483:Base Sequence; D013294:Lactococcus lactis / Q000821:virology*; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D014764:Viral Proteins / Q000502:physiology*
chemical_list: D001426:Bacterial Proteins; D014764:Viral Proteins