title: Metastatic mesothelioma presenting with proptosis.
abstract: OBJECTIVE
  To describe the clinical presentation and histologic findings in a patient with metastatic mesothelioma presenting to the ophthalmologist with nonaxial proptosis.
  
  
  METHODS
  Case report.
  
  
  METHODS
  A 55-year-old man presented with a short history of progressive ocular discomfort and vertical diplopia. Clinical examination identified nonaxial proptosis. Subsequent computed tomography showed a large extraconal mass consistent with a malignant process. Three months earlier the patient had been diagnosed with pleural mesothelioma. Unfortunately, he died 3 months after his ophthalmic presentation. Postmortem examination confirmed metastatic mesothelioma in the orbital roof that was histologically identical to the primary pleural malignancy.
  
  
  CONCLUSIONS
  Pleural mesothelioma can metastasize to the orbit, causing proptosis.
authors.affiliation: Prince Charles Eye Unit, King Edward VII Hospital, Windsor, United Kingdom. agibson@tinyonline.co.uk
authors.forename: Andrew
authors.initials: A
authors.lastname: Gibson
authors.forename: Fawaz
authors.initials: F
authors.lastname: Musa
authors.forename: Andrew
authors.initials: A
authors.lastname: Pearson
authors.forename: John
authors.initials: J
authors.lastname: Wiggins
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D005094:Exophthalmos / Q000175:diagnosis*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000737:chemistry / Q000000981:diagnostic imaging / Q000556:secondary*; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging / Q000556:secondary*; D010997:Pleural Neoplasms / Q000737:chemistry / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor