Histological findings in "incidental" intraoperative pancreas allograft biopsies.
Thirty intraoperative needle core biopsies of well-functioning pancreas allografts were performed from 2 days to 7 years posttransplantation (mean 15.4 months). Most samples (83.3%) lacked significant inflammation or fibrosis. The five patients who showed features of ongoing low-grade acute rejection experienced premature graft losses due to chronic rejection. There were no complications related to the intraoperative biopsy itself.
Drachenberg
C B
CB
Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Papadimitriou
J C
JC
Schweitzer
E
E
Philosophe
B
B
Foster
C
C
Bartlett
S T
ST
D000328:Adult; D001707:Biopsy, Needle; D005260:Female; D005355:Fibrosis; D006084:Graft Rejection / Q000473:pathology*; D006801:Humans; D033162:Incidental Findings; D007249:Inflammation; D007813:Laparotomy; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D016035:Pancreas Transplantation / Q000473:pathology*; D014184:Transplantation, Homologous / Q000473:pathology