title: An evaluation of postoperative P-wave variables after cardiothoracic surgery.
abstract: Postoperative atrial fibrillation is common after cardiac surgery. Prediction of which patients will develop postoperative atrial fibrillation would be clinically useful. Increased P-wave duration, suggesting atrial conduction delay and measured from preoperative electrocardiograms, predicts postoperative atrial fibrillation. However, postoperative P-wave duration has not been evaluated after cardiac surgery. In this study, we evaluated postoperative P-wave variables (maximum P-wave duration and P-wave dispersion) over 5 days in cardiac surgery patients receiving amiodarone, pacing or no atrial fibrillation prophylaxis. P-wave variables gradually shortened as time passed from surgery. Amiodarone did not shorten P-wave measurements throughout therapy, while pacing shortened P-waves in the immediate postoperative period; however, shortening was not sustained. P-waves did not differ between those who did and did not develop atrial fibrillation with amiodarone or pacing. Our findings suggest that atrial conduction delay resulting from cardiothoracic surgery tends to resolve over time and may not play a critical role in the etiology of postoperative atrial fibrillation.
authors.affiliation: Wayne State University, College of Pharmacy and Henry Ford Hospital, Detroit, MI, USA.
authors.forename: James S
authors.initials: JS
authors.lastname: Kalus
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Kluger
authors.forename: Michael F
authors.initials: MF
authors.lastname: Caron
authors.forename: Xinhcun
authors.initials: X
authors.lastname: Liu
authors.forename: Chester
authors.initials: C
authors.lastname: Humphrey
authors.forename: C Michael
authors.initials: CM
authors.lastname: White
mesh_terms: D000368:Aged; D000638:Amiodarone / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000209:etiology* / Q000517:prevention & control; D002304:Cardiac Pacing, Artificial; D006348:Cardiac Surgical Procedures; D004562:Electrocardiography; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications
chemical_list: D000638:Amiodarone