title: Computerized adaptive measurement of depression: a simulation study.
abstract: BACKGROUND
  Efficient, accurate instruments for measuring depression are increasingly important in clinical practice. We developed a computerized adaptive version of the Beck Depression Inventory (BDI). We examined its efficiency and its usefulness in identifying Major Depressive Episodes (MDE) and in measuring depression severity.
  
  
  METHODS
  Subjects were 744 participants in research studies in which each subject completed both the BDI and the SCID. In addition, 285 patients completed the Hamilton Depression Rating Scale.
  
  
  RESULTS
  The adaptive BDI had an AUC as an indicator of a SCID diagnosis of MDE of 88%, equivalent to the full BDI. The adaptive BDI asked fewer questions than the full BDI (5.6 versus 21 items). The adaptive latent depression score correlated r =.92 with the BDI total score and the latent depression score correlated more highly with the Hamilton (r =.74) than the BDI total score did (r =.70).
  
  
  CONCLUSIONS
  Adaptive testing for depression may provide greatly increased efficiency without loss of accuracy in identifying MDE or in measuring depression severity.
authors.affiliation: Pediatrics, Children's Research Institute and Ohio State University, Columbus, OH, USA. gardnerw@pediatrics.ohio-state.edu
authors.forename: William
authors.initials: W
authors.lastname: Gardner
authors.forename: Katherine
authors.initials: K
authors.lastname: Shear
authors.forename: Kelly J
authors.initials: KJ
authors.lastname: Kelleher
authors.forename: Kathleen A
authors.initials: KA
authors.lastname: Pajer
authors.forename: Oommen
authors.initials: O
authors.lastname: Mammen
authors.forename: Daniel
authors.initials: D
authors.lastname: Buysse
authors.forename: Ellen
authors.initials: E
authors.lastname: Frank
mesh_terms: D000328:Adult; D000465:Algorithms; D019540:Area Under Curve; D003198:Computer Simulation; D003866:Depressive Disorder / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology; D003936:Diagnosis, Computer-Assisted / Q000379:methods* / Q000706:statistics & numerical data; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D020407:Internet; D008297:Male; D008403:Mass Screening / Q000379:methods; D018579:Patient Selection; D010555:Personality Inventory / Q000706:statistics & numerical data*; D010865:Pilot Projects; D015995:Prevalence; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data*; D011594:Psychometrics; D012720:Severity of Illness Index; D012984:Software