Psychometric validation of the Hungarian translation of the gastrointestinal symptom rating scale (GSRS) and quality of life in reflux and dyspepsia (QOLRAD) questionnaire in patients with reflux disease.
BACKGROUND
Symptoms of heartburn and their impact on health-related quality of life (HRQL) are often evaluated in clinical trials. When a questionnaire is translated into a new language, a linguistic validation is necessary but not sufficient unless the psychometric characteristics have been verified. The aim of the paper is to document the psychometric characteristics of the Hungarian translation of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire.


METHODS
One hundred and thirty-six patients with symptoms of heartburn (age: M = 47.3, SD = 13.4; females = 58.1%) completed the Hungarian translation of GSRS, the heartburn version of QOL-RAD, the Short-Form-36 (SF-36) and the Hospital Anxiety and Depression (HAD) scale. Eighty-seven patients were scheduled for a second visit a week later to complete the GSRS and QOLRAD again.


RESULTS
The internal consistency reliability of GSRS ranged from 0.62-0.84 and of QOLRAD from 0.88-0.94, and the test-retest reliability of GSRS ranged from 0.52-0.82 and of QOLRAD from 0.68-0.82. The relevant domains of the GSRS, 'Reflux', 'Abdominal Pain' and 'Indigestion', and QOLRAD domain scores significantly correlated. All GSRS domains except 'Reflux' strongly correlated (negatively) with all SF-36 domains. All QOLRAD domains significantly correlated with all SF-36 domains.


CONCLUSIONS
The psychometric characteristics of the Hungarian translations of GSRS and QOLRAD were found to be good, with satisfactory reliability and validity. The test-retest reliability of the GSRS 'Reflux' domain was, however, not optimal.
Kulich
R Károly
RK
AstraZeneca R&D Mölndal, Sweden. Karoly.Kulich@astrazeneca.com
Ujszászy
László
L
Tóth
G Tamás
GT
Bárány
László
L
Carlsson
Jonas
J
Wiklund
Ingela
I
D000328:Adult; D004415:Dyspepsia / Q000175:diagnosis*; D005260:Female; D005764:Gastroesophageal Reflux / Q000175:diagnosis*; D006801:Humans; D006814:Hungary; D008297:Male; D008875:Middle Aged; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D014177:Translations