title: Comparison of wear and osteolysis in hip replacement using two different coatings of the femoral stem.
abstract: We compared the clinical and radiographic results of two matched series of total hip arthroplasties, one with hydroxyapatite-coated femoral stems, the other with a similar but porous-coated femoral stem. The prevalence of radiographic osteolysis was 16% in hips with hydroxyapatite-coated stems and 43% in hips with porous-coated femoral stems. In hips with hydroxyapatite-coated stems, osteolysis was always limited to Gruen zones 1 and 7. In contrast, distal osteolysis was present around 26% of the porous-coated stems. At 7 years, the survival-free rate of distal osteolysis was 100% in hips with hydroxyapatite-coated stems but 90% in hips with porous-coated stems (p=0.04). Circumferential hydroxyapatite coating of the femoral component reduced the occurrence of osteolysis and eliminated distal osteolysis at 5-10 years of follow-up. In addition, hydroxyapatite coating did not alter the wear rate.
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
authors.forename: Joaquin
authors.initials: J
authors.lastname: Sanchez-Sotelo
authors.forename: David G
authors.initials: DG
authors.lastname: Lewallen
authors.forename: William Scott
authors.initials: WS
authors.lastname: Harmsen
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Harrington
authors.forename: Miguel E
authors.initials: ME
authors.lastname: Cabanela
mesh_terms: D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D020099:Coated Materials, Biocompatible; D017886:Durapatite; D005260:Female; D005269:Femur / Q000601:surgery*; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010014:Osteolysis / Q000453:epidemiology*; D011446:Prospective Studies; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012086:Reoperation; D016019:Survival Analysis
chemical_list: D020099:Coated Materials, Biocompatible; D017886:Durapatite