title: Chromatographic impulse response technique with curve fitting to measure binary diffusion coefficients and retention factors using polymer-coated capillary columns.
abstract: The theoretical basis of a Gaussian-like approximate solution was applied to a chromatographic impulse response technique with curve fitting for measuring binary diffusion coefficients and retention factors using a polymer-coated capillary column. The formulae were derived for evaluating both the accuracy of the approximate solution and the sensitivity of the parameters. The validity of the solution also was confirmed experimentally for pulse injection of phenol in acetone into supercritical carbon dioxide flowing at 313.15 K and 11.6-28.6 MPa. Potential sources for experimental errors of the method are discussed.
authors.affiliation: Faculty of Environment and Information Sciences, Yokohama National University, 79-7 Tokiwadai, Hodogaya-ku, Yokohama 240-8501, Japan. kong@ynu.ac.jp
authors.forename: Chang Yi
authors.initials: CY
authors.lastname: Kong
authors.forename: Toshitaka
authors.initials: T
authors.lastname: Funazukuri
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Kagei
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation*; D004058:Diffusion; D011108:Polymers / Q000737:chemistry*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D011108:Polymers