title: Synthesis and evaluation of oxazaborolidines for antibacterial activity against Streptococcus mutans.
abstract: Several representative oxazaborolidines have been synthesized and evaluated against S. mutans for antibacterial activity. This is the first reported antibacterial activity of this class of compounds. The minimal inhibitory concentration values ranged from 0.53 to 6.75 mM.
authors.affiliation: Department of Medicinal Chemistry and Natural Products, School of Pharmacy, and Faculty of Dentistry, Institute of Dental Sciences, Hebrew University, Jerusalem 91120, Israel.
authors.forename: Adel
authors.initials: A
authors.lastname: Jabbour
authors.forename: Doron
authors.initials: D
authors.lastname: Steinberg
authors.forename: Valery M
authors.initials: VM
authors.lastname: Dembitsky
authors.forename: Arieh
authors.initials: A
authors.lastname: Moussaieff
authors.forename: Batia
authors.initials: B
authors.lastname: Zaks
authors.forename: Morris
authors.initials: M
authors.lastname: Srebnik
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006573:Heterocyclic Compounds, 1-Ring / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D013237:Stereoisomerism; D013295:Streptococcus mutans / Q000187:drug effects*; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D001896:Boron Compounds; D006573:Heterocyclic Compounds, 1-Ring