title: Genetic susceptibility to breast and ovarian cancer: risk assessment, genetic counseling, and management issues.
abstract: Genetic testing for disease susceptibility genes is available for a large number of genetic disorders. With the expected shortage of trained genetic professionals to offer risk assessment, counseling, testing, and management to patients, primary care physicians will be asked to provide these services. In this review, we discuss the genetic basis of breast and ovarian cancer susceptibility and outline specific recommendations for clinical practice.
authors.affiliation: Division of Medical Genetics, Department of Pediatrics, Saint Louis University School of Medicine, USA.
authors.forename: Maulik R
authors.initials: MR
authors.lastname: Shah
mesh_terms: D000465:Algorithms; D001943:Breast Neoplasms / Q000175:diagnosis / Q000235:genetics*; D003376:Counseling; D005260:Female; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D005826:Genetics, Medical / Q000379:methods* / Q000639:trends; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000235:genetics*; D018570:Risk Assessment