[Leptin concentration in women with normal pregnancy and intrauterine growth retardation].
OBJECTIVE
Leptin takes part in fat regulation and can also take part in regulation of prenatal fetal weight.


METHODS
The aim of the study was to find correlation between leptin concentration in healthy women and intrauterine growth restriction.


METHODS
The study was done in Medical University in Lodz in 2000-2002. The study group consisted of 50 women with IUGR, the control group of 50 healthy pregnant women. Elisa immunoenzymatic IBL test was used. The results were expressed in microgram/l.


RESULTS
In group of normal pregnancy leptin concentration was 5.347 +/- 1.098 micrograms/l. In group of intrauterine growth restriction leptin concentration was 4.617 +/- 0.949 micrograms/l. The difference between groups was statistically significant but the mean values in both groups were normal for nonpregnant women.


CONCLUSIONS
Low concentration of leptin can play role in intrauterine growth restriction.
Karowicz-Bilińska
Agata
A
Kliniki Patologii Ciazy Instytutu Ginekologii i Połoznictwa UM w łodzi.
D000328:Adult; D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D005317:Fetal Growth Retardation / Q000097:blood* / Q000209:etiology; D006801:Humans; D020738:Leptin / Q000097:blood*; D011247:Pregnancy / Q000097:blood*; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D013997:Time Factors
D020738:Leptin