title: Absolute dosimetry in a d(14 MeV) + Be fast neutron beam.
abstract: Since 1978, the Universitätsklinikum in Essen operates a d(14 MeV) + Be fast neutron beam for patient treatment. Dosimetric studies were performed in a rectangular 40 x 40 mm2 neutron/photon field using a transportable water calorimeter, which had been developed at the Physikalisch-Technische Bundesanstalt. The water calorimeter allowed small dosimeters to be directly calibrated in units of absorbed dose-to-water in a cylindrical phantom of 50 mm in diameter. Also, the twin detector method was applied in order to determine the photon and the neutron dose separately. By making use of a calibrated ionization chamber, the absorbed dose-to-water calibration in the cylindrical water phantom was transferred to a water phantom, a cube 300 mm on a side. Experiments and Monte Carlo calculations covering the neutron producing target, the collimator and the influence of the water calorimeter on the spectral neutron fluence at the measurement position allow the relative uncertainty of the absorbed dose-to-water determination to be reduced to 2.6% (1 SD). This direct absorbed dose-to-water determination by calorimetry has shown that the treatment planning system underestimates the physical dose to tissue by 9%. For clinical purposes, the statement of the prescribed dose had to be increased by 9% in order that the absolute absorbed dose remains constant and that the same biological endpoints are reached.
authors.affiliation: Strahlenklinik, Universitätsklinikum Essen, Hufelandstr. 55, 45122 Essen, Germany. emmanuelle.bourhis@uni-essen.de
authors.forename: E
authors.initials: E
authors.lastname: Bourhis-Martin
authors.forename: H J
authors.initials: HJ
authors.lastname: Brede
authors.forename: K D
authors.initials: KD
authors.lastname: Greif
authors.forename: W
authors.initials: W
authors.lastname: Baumhoer
authors.forename: J
authors.initials: J
authors.lastname: Rassow
authors.forename: W
authors.initials: W
authors.lastname: Sauerwein
mesh_terms: D016754:Boron Neutron Capture Therapy / Q000295:instrumentation* / Q000379:methods; D002138:Calibration / Q000592:standards; D002151:Calorimetry / Q000295:instrumentation* / Q000379:methods / Q000592:standards*; D019544:Equipment Failure Analysis / Q000379:methods / Q000592:standards; D011785:Quality Assurance, Health Care / Q000379:methods* / Q000592:standards; D011829:Radiation Dosage; D011874:Radiometry / Q000295:instrumentation* / Q000379:methods / Q000592:standards*; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation* / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity