title: Administration of Zn-Co-Mn basic salt to chickens with ascaridiosis. I. A mathematical model for Ascaridia galli populations and host growth with and without treatment.
abstract: A newly synthesized basic mixed salt (Zn(x)Co(y)Mn(1-x-y)) x (OH)6SO4 x 2H2O) was administered to chickens with ascaridiosis. Improvement in survival, gain in body weight (of 19.03%) and restoration of microelement content were observed in the treated chickens. An increase in the gain in body weight of 7.62% in uninfected treated chickens was also observed. The establishment of Ascaridia galli populations in chickens, and chicken growth in control and infected hosts, untreated and treated, were modelled mathematically. Some kinetic parameters (the rate of reduction of the nematode population nu and the relative rate mu of gain in body weight of the host) were determined. The values of nu =0.027 day(-1) and nu* =0.032 day(-1) were calculated for the reduction rates in infected, untreated chickens and in infected, treated chickens, respectively. The worm burden in infected, treated chickens was 20.4% lower than in infected, untreated chickens.
authors.affiliation: Institute for Experimental Pathology and Parasitology, Bulgarian Academy of Sciences, Acad G Bonchev str, bl 25, 1113 Sofia, Bulgaria.
authors.forename: M
authors.initials: M
authors.lastname: Gabrashanska
authors.forename: S E
authors.initials: SE
authors.lastname: Teodorova
authors.forename: M M
authors.initials: MM
authors.lastname: Galvez-Morros
authors.forename: N
authors.initials: N
authors.lastname: Tsocheva-Gaytandzhieva
authors.forename: M
authors.initials: M
authors.lastname: Mitov
mesh_terms: D000818:Animals; D001197:Ascaridia / Q000187:drug effects / Q000502:physiology*; D001198:Ascaridiasis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D001835:Body Weight / Q000187:drug effects; D002645:Chickens / Q000254:growth & development / Q000469:parasitology*; D003035:Cobalt / Q000627:therapeutic use; D004064:Digestive System / Q000469:parasitology; D006790:Host-Parasite Interactions; D008297:Male; D008345:Manganese / Q000627:therapeutic use; D008433:Mathematics; D008954:Models, Biological; D011201:Poultry Diseases / Q000188:drug therapy / Q000469:parasitology; D012492:Salts; D016019:Survival Analysis; D014131:Trace Elements / Q000008:administration & dosage / Q000627:therapeutic use*; D015032:Zinc / Q000627:therapeutic use
chemical_list: D012492:Salts; D014131:Trace Elements; D003035:Cobalt; D008345:Manganese; D015032:Zinc