Sablacaurin A and B, two 19-nor-3,4-seco-lanostane-type triterpenoids from Sabal causiarum and Sabal blackburniana, respectively.
In search for bioactive compounds from Sabal species, sablacaurin A [25-ethyl,23-methyl-19-nor-24-methylene-3,4-seco-4(28)-lanosten-10,3-olide] and sablacaurin B [24-ethyl,24-methyl-19-nor-3,4-seco-4(28),25(26)-lanostadiene-10,3-olide], the first 19-nor lanostane derivatives of the 3,4-seco type with a spiro element, have been isolated from the leaves of Sabal causiarum and Sabal blackburniana respectively, together with the known squalene (S. blackburniana) and ss-sitosterol (S. causiarum). From leaves of Sabal peregrina, the known triterpenes 3-oxo-24-methylenecycloartane and 24-methylcycloart-25(26)-en-3-one were isolated. The structures of these compounds were established from spectroscopic studies.
El-Dib
Rabab
R
Freie Universität Berlin, Institut für Pharmazie, Pharmazeutische Biologie, Königin-Luise-Str. 2+4, D-14195 Berlin, Germany.
Kaloga
Maki
M
Mahmoud
Ibrahim
I
Soliman
Hesham S M
HS
Moharram
Fatma A
FA
Kolodziej
Herbert
H
D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D028024:Serenoa / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
D014315:Triterpenes