title: Effects of polymerization initiator complexation in methacrylated beta-cyclodextrin formulations.
abstract: OBJECTIVE
  Methacrylated beta-cyclodextrin (MCD) is a candidate dental monomer that can complex molecules within its hydrophobic cavity. This study determined the effects of complexation of polymerization initiators such as camphorquinone (CQ) and ethyl-4-dimethylaminobenzoate (4E) with MCD on the flexural strength (FS) and degree of conversion (DC) of resulting dental composite formulations.
  
  
  METHODS
  Complexation of CQ and 4E with MCD was studied by thin layer chromatography. A mass fraction of 44% 2-hydroxyethylmethacrylate or triethyleneglycoldimethacrylate was mixed separately with a mass fraction of 56% MCD to produce a workable formulation. The mixture was activated with varied amounts of CQ and 4E. One part by mass of the activated resin formulation was mixed with three parts by mass of glass filler. Specimens for FS were prepared by filling molds with composites and curing for 2 min. The cured specimens were immersed in 37 degrees C water for 24 h and FS was measured with an Instron machine at a crosshead speed of 0.5 mm/min. DC in MCD-based resin formulations was measured with a differential photocalorimeter under nitrogen.
  
  
  RESULTS
  MCD appears to form inclusion complexes with CQ and 4E. As a result, FS and DC of MCD-based composites vary significantly as a function of the concentration of polymerization initiators used in the formulations.
  
  
  CONCLUSIONS
  Complexation of polymerization initiators with MCD can influence the FS and DC in MCD-based dental formulations and should be taken into consideration when evaluating MCD as a dental monomer.
authors.affiliation: Paffenbarger Research Center, American Dental Association Health Foundation, National Institute of Standards and Technology, 100 Bureau Drive, Stop 8546, Gaithersburg, MD 20899, USA. latiff.hussain@nist.gov
authors.forename: Latiff A
authors.initials: LA
authors.lastname: Hussain
authors.forename: Sabine H
authors.initials: SH
authors.lastname: Dickens
authors.forename: Rafael L
authors.initials: RL
authors.lastname: Bowen
mesh_terms: D062365:Aminobenzoates / Q000737:chemistry; D000704:Analysis of Variance; D003188:Composite Resins / Q000737:chemistry*; D003505:Cyclodextrins / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry; D015394:Molecular Structure; D044367:Phase Transition; D018583:Pliability; D018709:Statistics, Nonparametric; D013729:Terpenes / Q000737:chemistry; D047392:beta-Cyclodextrins
chemical_list: D062365:Aminobenzoates; D003188:Composite Resins; D003505:Cyclodextrins; D008689:Methacrylates; D013729:Terpenes; D047392:beta-Cyclodextrins; C048339:camphoroquinone; C031215:betadex