Methyl 2,6-di-O-benzyl-3,4-O-phenylphosphinediyl-beta-D-galactopyranoside(P-B)borane with chirality on the P atom.
A carbohydrate-derived optically active P-chiral dioxophenylphospholane-borane complex, C(27)H(32)BO(6)P, was prepared from bis(diethylamino)phenylphosphine and methyl 2,6-di-O-benzyl-beta-D-galactopyranoside. The phosphinite was prepared with high diastereoselectivity and in good yield. The absolute configuration (R) at the P atom was deduced from the known configuration of the sugar moiety. Weak intermolecular interactions link the molecules into a three-dimensional network.
Johansson
Magnus J
MJ
Department of Chemistry and Bioscience, Chalmers University of Technology, SE-412 96 Göteborg, Sweden. magjo@chembio.chalmers.se
Bergh
Anders
A
Larsson
Krister
K