title: Surgical reconstruction of occluded pulmonary arteries in patients with congenital heart disease: effects on pulmonary artery growth.
abstract: BACKGROUND
  This study was undertaken to determine outcomes and best strategies for treatment of occluded pulmonary arteries in patients with congenital heart disease.
  
  
  RESULTS
  Between 1998 and 2002, occlusion of a previously patent pulmonary artery was established in 23 patients. Data were obtained retrospectively. Diagnoses were pulmonary atresia and ventricular septal defect in 11, tetralogy of Fallot in 6, and other forms of pulmonary stenosis or atresia in 6. Median age and weight at diagnosis were 9 years (range, 6 days to 43 years) and 24 kg (range, 2.6 to 60 kg). Fourteen patients had had a previous surgery. The occluded pulmonary artery was visualized at angiography by wedge injection or injection into the collateral circulation. The left pulmonary artery was occluded in 20 patients and the right pulmonary artery in 3. Criteria for reconstruction were estimated duration of occlusion <6 months and ratio of occluded to contralateral artery >0.2. Twelve patients fulfilled these criteria and underwent pulmonary artery reconstruction at a mean interval of 2 months (range, 6 days to 6 months) from evidence of occlusion. Six patients had pericardial patch reconstruction, 3 terminoterminal anastomosis, 2 thrombectomy, and 1 a Blalock-Taussig shunt. There was 1 late death. At a median follow-up of 4 years (2 months to 5 years), all patients underwent cardiac catheterization: in 8 patients the reconstructed artery was patent, in 3 reoccluded. Hypoplasia of the occluded artery was reversed in 6 patients.
  
  
  CONCLUSIONS
  Our data show that in selected patients, reconstruction of an occluded pulmonary artery can restore pulmonary vascularization and reverse hypoplasia. Strict surveillance is mandatory to prevent pulmonary artery loss.
authors.affiliation: Service de Cardiologie Pédiatrique, Groupe Hospitalier Necker Enfants Malades, 149, rue de Sèvres, 75743 Paris, France. gabriella.agnoletti@nck.ap-hop-paris.fr
authors.forename: Gabriella
authors.initials: G
authors.lastname: Agnoletti
authors.forename: Younes
authors.initials: Y
authors.lastname: Boudjemline
authors.forename: Damien
authors.initials: D
authors.lastname: Bonnet
authors.forename: Daniel
authors.initials: D
authors.lastname: Sidi
authors.forename: P
authors.initials: P
authors.lastname: Vouhé
mesh_terms: D000293:Adolescent; D000328:Adult; D006328:Cardiac Catheterization; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006345:Heart Septal Defects, Ventricular / Q000601:surgery; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000254:growth & development / Q000601:surgery*; D018633:Pulmonary Atresia / Q000601:surgery*; D011666:Pulmonary Valve Stenosis / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods / Q000706:statistics & numerical data; D012008:Recurrence; D013771:Tetralogy of Fallot / Q000601:surgery*; D016896:Treatment Outcome