Depressed mood impedes pain treatment response in patients with fibromyalgia.
OBJECTIVE
To investigate prognostic factors in the course of the fibromyalgia syndrome (FM) from baseline to post-treatment.


METHODS
Fifty-seven patients with FM were examined in a randomized intervention study. Pre-treatment variables were entered into linear regression analyses: gender, age, duration of disease, allocation to treatment, pain distribution (based on a patient-made drawing), fatigue, sleep disturbance, and depressed mood (based on visual analog scores), with pain distribution at treatment completion as the dependent variable.


RESULTS
Depressed mood at baseline was a significant predictor of sustained widespread pain at treatment completion.


CONCLUSIONS
The findings indicate a role for depressed mood as a predictive factor for treatment response.
Finset
Arnstein
A
Department of Behavioural Sciences in Medicine, University of Oslo, Oslo, Norway. arnstein.finset@basalmed.uio.no
Wigers
Sigrid Hørven
SH
Götestam
K Gunnar
KG
D000328:Adult; D000368:Aged; D003863:Depression / Q000150:complications*; D005081:Exercise Therapy; D005221:Fatigue / Q000150:complications; D005260:Female; D005356:Fibromyalgia / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000150:complications / Q000175:diagnosis; D059408:Pain Management; D011379:Prognosis; D012893:Sleep Wake Disorders / Q000150:complications; D016896:Treatment Outcome