title: Applied biocatalysis for the synthesis of natural flavour compounds--current industrial processes and future prospects.
abstract: The industrial application of biocatalysis for the production of natural flavour compounds is illustrated by a discussion of the production of vanillin, gamma-decalactone, carboxylic acids, C6 aldehydes and alcohols ('green notes'), esters, and 2-phenylethanol. Modern techniques of molecular biology and process engineering, such as heterologous expression of genes, site-directed mutagenesis, whole-cell biocatalysis in biphasic systems, and cofactor regeneration for in vitro oxygenation, may result in more biocatalytic processes for the production of flavour compounds in the future.
authors.affiliation: Karl Winnacker Institute, DECHEMA e.V., Theodor-Heuss-Allee 25, 60486 Frankfurt/Main, Germany. schrader@dechema.de
authors.forename: J
authors.initials: J
authors.lastname: Schrader
authors.forename: M M W
authors.initials: MM
authors.lastname: Etschmann
authors.forename: D
authors.initials: D
authors.lastname: Sell
authors.forename: J M
authors.initials: JM
authors.lastname: Hilmer
authors.forename: J
authors.initials: J
authors.lastname: Rabenhorst
mesh_terms: D001709:Biotechnology / Q000639:trends*; D002384:Catalysis; D004798:Enzymes / Q000235:genetics / Q000378:metabolism*; D005421:Flavoring Agents / Q000138:chemical synthesis*; D015870:Gene Expression / Q000235:genetics; D005818:Genetic Engineering / Q000379:methods; D016297:Mutagenesis, Site-Directed
chemical_list: D004798:Enzymes; D005421:Flavoring Agents