title: Backside wear of modular ultra-high molecular weight polyethylene tibial inserts.
abstract: BACKGROUND
  The capture mechanisms of modular tibial total knee components may allow relative micromotion between the insert and the base-plate, leading to wear at the nonarticulating (backside) surface. Although retrieved components often display laxity in the capture mechanism in the unloaded condition, the magnitude of the relative motion that actually occurs under physiologic conditions has not been determined. This study was performed to assess the impact of different modes of knee-loading on the relative micromotion between the insert and the base-plate and the relationship between the duration that the implant had been in situ and the severity of backside wear.
  
  
  METHODS
  Twenty-one posterior-stabilized total knee replacements of one common design (Insall-Burstein II) were retrieved at one to 100 months after implantation. The extent and severity of backside wear was graded with use of stereomicroscopy. All components were soaked in a bath (of physiologic saline solution at 37 degrees C for four days prior to reassembly. The relative micromotion between the insert and the base-plate of each specimen was measured in vitro in two different conditions: with no axial load and with a combination of loads and torques simulating the stance phase of gait.
  
  
  RESULTS
  The capture mechanism laxity between the insert and the tibial base-plate in the unloaded condition was approximately eight times larger than the micromotion measured during simulated gait. The capture mechanism laxity allowed a mean (and standard deviation) of 618 +/- 226 micro m of total relative micromotion compared with 103 +/- 54 micro m of relative micromotion during the gait cycle. Under both loading conditions, the predominant direction of interface motion was medial-lateral. No correlation was found between the magnitude of capture mechanism laxity and the relative micromotion measured during simulated gait (p = 0.11). Larger polyethylene protrusions on the backside surface did not correlate with less micromotion (p = 0.48) or with capture mechanism laxity (p = 0.06).
  
  
  CONCLUSIONS
  For the implant design that was studied, capture mechanism laxity between the modular insert and the base-plate in the unloaded condition was an order of magnitude larger than and not indicative of the micromotion that occurred during simulated physiologic loading. In addition, polyethylene protrusions into the screw-holes of tibial base-plates did not seat or lock the insert in place and reduce relative motion.
  
  
  CONCLUSIONS
  While some clearance between the insert and the base-plate is required to allow assembly of modular tibial components at the time of surgery, the amount of relative interface motion during a functional activity such as normal gait, which can produce potentially damaging wear debris, is unknown. However, the compressive forces applied to the articular surface during a functional activity may substantially reduce micromotion between the insert and the base-plate relative to the unloaded condition.
authors.affiliation: Institute of Orthopedic Research and Education, Houston, TX 77030, USA. mconditt@bcm.tmc.edu.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Conditt
authors.forename: Sabir K
authors.initials: SK
authors.lastname: Ismaily
authors.forename: Jerry W
authors.initials: JW
authors.lastname: Alexander
authors.forename: Philip C
authors.initials: PC
authors.lastname: Noble
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation; D001672:Biocompatible Materials / Q000627:therapeutic use*; D004867:Equipment Design; D005260:Female; D005684:Gait; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D020959:Polyethylene / Q000627:therapeutic use*; D011475:Prosthesis Failure; D012086:Reoperation; D016474:Weight-Bearing
chemical_list: D001672:Biocompatible Materials; D020959:Polyethylene