title: Bio-bar-code-based DNA detection with PCR-like sensitivity.
abstract: Novel two-component oligonucleotide-modified nanoparticle probes have been designed and used in a bio-bar-code assay with a 500 zeptomolar target DNA sensitivity limit.
authors.affiliation: Department of Chemistry and Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, USA.
authors.forename: Jwa-Min
authors.initials: JM
authors.lastname: Nam
authors.forename: Savka I
authors.initials: SI
authors.lastname: Stoeva
authors.forename: Chad A
authors.initials: CA
authors.lastname: Mirkin
mesh_terms: D004247:DNA / Q000235:genetics*; D015342:DNA Probes; D006046:Gold; D008280:Magnetics; D008863:Microspheres; D036103:Nanotechnology; D021141:Nucleic Acid Amplification Techniques; D009841:Oligonucleotides / Q000032:analysis; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017422:Sequence Analysis, DNA
chemical_list: D015342:DNA Probes; D009841:Oligonucleotides; D006046:Gold; D004247:DNA