Unilateral deep brain stimulation of the internal globus pallidus alleviates tardive dyskinesia.
We describe a patient with fluspirilene-induced tardive dyskinesia of the choreiform oro-facial-laryngeal type resistant to various conservative approaches for 7 years who underwent deep brain stimulation of the internal pallidal globe. We found immediate and marked suppression of her perioral involuntary movements with unilateral stimulation at 60 Hz.
Schrader
Christoph
C
Department of Neurology, Medizinische Hochschule Hannover, Hannover, Germany. schrader.christoph@mh-hannover.de
Peschel
Thomas
T
Petermeyer
Michael
M
Dengler
Reinhard
R
Hellwig
Dieter
D
D000368:Aged; D004311:Double-Blind Method; D004409:Dyskinesia, Drug-Induced / Q000175:diagnosis / Q000601:surgery*; D004558:Electric Stimulation / Q000295:instrumentation; D004567:Electrodes, Implanted; D005260:Female; D005917:Globus Pallidus / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D011795:Surveys and Questionnaires; D014743:Videotape Recording