Solitary nonepitheliotropic T-cell lymphoma in a dog.
A 7-year-old male Golden Retriever with swelling of the rostral bridge and right wing of the nasal areas, sneezing, and inspiratory difficulty was referred to a neighbor veterinarian. Except for those in the nasal area, no lesions were noted during routine physical examination. The mass occupying the nasal cavity was not observed radiographically. Punch biopsy of the affected lesions revealed nonepitheliotropic lymphoma. Immunohistochemical staining for CD3 antigen was positive. The dog was diagnosed with solitary nonepitheliotropic T-cell lymphoma. Local radiotherapy and systemic chemotherapy with doxorubicin were instituted and resulted in total clinical remission. The dog has remained disease free for 30 months.
Ueno
Hiroshi
H
Department of Clinical Veterinary Sciences, Obihiro University of Agriculture and Veterinary Medicine, Japan.
Isomura
Hiroshi
H
Tanabe
Shigeyuki
S
Tabuchi
Hiroyuki
H
Yamada
Kazutaka
K
Sato
Motoyoshi
M
D000818:Animals; D001706:Biopsy; D017252:CD3 Complex; D004283:Dog Diseases / Q000188:drug therapy* / Q000473:pathology*; D004285:Dogs; D004317:Doxorubicin / Q000627:therapeutic use*; D007150:Immunohistochemistry; D016399:Lymphoma, T-Cell / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*
D017252:CD3 Complex; D004317:Doxorubicin