Application of comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry in the analysis of volatile oil of traditional Chinese medicines.
This paper reports comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry (GC x GC-TOF MS) analysis of Pogostemon cablin Benth (Cablin Parchouli) volatile oil. The suitable column system and operation conditions were chosen on the basis of the properties of composition of the volatile oil. One-dimensional gas chromatography (ID-GC) and GC x GC, GC-MS and GC x GC-TOF MS were compared under appropriate conditions, and the enhanced sensitivity and superior resolution of GC x GC were demonstrated. 394 components were tentatively identified by GC x GC-TOF MS.
Wu
Jianfang
J
National Chromatographic R&A Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116011, China.
Lu
Xin
X
Tang
Wanying
W
Kong
Hongwei
H
Zhou
Shenfan
S
Xu
Guowang
G
D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D008516:Medicine, Chinese Traditional; D009822:Oils, Volatile / Q000032:analysis*; D012680:Sensitivity and Specificity; D014835:Volatilization
D009822:Oils, Volatile