Solitary fibrous tumors of the meninges: report of four cases and literature review.
Central nervous system solitary fibrous tumors are a new pathological entity. To our knowledge, only 60 meningeal solitary fibrous tumors both in the spinal cord and in the brain have been described in the literature. The 56 previously reported cases of meningeal solitary fibrous tumors are critically reviewed. In addition, we report four new cases of solitary fibrous tumors of the meninges. There is a slight male prepoderance. Meningeal solitary fibrous tumors show a tendency to arise in the posterior fossa (26%) and spine (25%). The treatment was mainly total surgical excision. Radiotherapy was given only to four patients with tumors involving the cerebral parenchyma. Sporadic cases of recurrence and distant metastasis have been reported. The prognosis of meningeal solitary fibrous tumors is still unknown because the follow-up of the reported cases is short. It is probable that cases of solitary fibrous tumors of the meninges have been misdiagnosed as other tumors in the past. The best management of these tumors seems to be total surgical excision whenever possible. It is important that every new case of meningeal SFT be reported to throw light on this particular tumor and to affirm its status as a clinicopathological entity.
Caroli
Emanuela
E
Department of Neurological Sciences, Neurosurgery, University of Rome "La Sapienza", Via di Grottarossa 1035, Rome, Italy. manucarol2000@yahoo.it
Salvati
Maurizio
M
Orlando
Epimenio Ramundo
ER
Lenzi
Jacopo
J
Santoro
Antonio
A
Giangaspero
Felice
F
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology* / Q000601:surgery*; D008875:Middle Aged; D018218:Neoplasms, Fibrous Tissue / Q000473:pathology* / Q000601:surgery*; D011379:Prognosis