title: ScanProsite: a reference implementation of a PROSITE scanning tool.
abstract: Many different software tools are available publicly to scan the PROSITE database of protein families. However, none of them, to our knowledge, wholly implements the PROSITE syntax, or satisfies all the rules for scanning a pattern against a sequence. We hereby propose a strict definition of how a PROSITE pattern is to be scanned against a sequence, and provide a reference implementation of a tool to scan PROSITE patterns, rules and profiles against protein sequences.
authors.affiliation: Swiss Institute of Bioinformatics, Geneva, Switzerland.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Gattiker
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Gasteiger
authors.forename: Amos
authors.initials: A
authors.lastname: Bairoch
mesh_terms: D019295:Computational Biology; D030562:Databases, Protein; D020869:Gene Expression Profiling / Q000706:statistics & numerical data; D016415:Sequence Alignment / Q000706:statistics & numerical data; D012984:Software