Desymmetrization of meso-dienyne by asymmetric Pauson-Khand type reaction catalysts.
Desymmetrization of the meso dienynes, such as propargyl 1-vinylallyl N-tosylamides (1a-c) and propargyl 1-vinylallyl ethers (1d-e), by asymmetric Pauson-Khand type reaction catalysts was studied. The corresponding vinyl substituted bicyclic pentenones (2 and 3) were obtained with high diastereoselectivity and enantioselectivity.
Jeong
Nakcheol
N
Department of Chemistry, Division of Molecular Engineering and Chemistry, Korea University, Seoul, 136-701, Korea.
Kim
Dong Hoon
DH
Choi
Jun Hun
JH