title: Direct optical detection of singlet oxygen from a single cell.
abstract: Singlet oxygen has been detected in single nerve cells by its weak 1270 nm phosphorescence (a1deltag --> X3sigmag-) upon irradiation of a photosensitizer incorporated in the cell. Thus, one can now consider the application of direct optical imaging techniques to mechanistic studies of singlet oxygen at the single-cell level.
authors.affiliation: Department of Chemistry, University of Aarhus, Arhus, Denmark.
authors.forename: Ingo
authors.initials: I
authors.lastname: Zebger
authors.forename: John W
authors.initials: JW
authors.lastname: Snyder
authors.forename: Lars Klembt
authors.initials: LK
authors.lastname: Andersen
authors.forename: Lars
authors.initials: L
authors.lastname: Poulsen
authors.forename: Zhan
authors.initials: Z
authors.lastname: Gao
authors.forename: John D C
authors.initials: JD
authors.lastname: Lambert
authors.forename: Uffe
authors.initials: U
authors.lastname: Kristiansen
authors.forename: Peter R
authors.initials: PR
authors.lastname: Ogilby
mesh_terms: D000818:Animals; D006624:Hippocampus / Q000737:chemistry; D049449:Luminescence; D008433:Mathematics; D009474:Neurons / Q000737:chemistry*; D010777:Photochemistry; D017319:Photosensitizing Agents / Q000737:chemistry*; D011166:Porphyrins / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D026082:Singlet Oxygen / Q000032:analysis*; D013053:Spectrophotometry / Q000379:methods
chemical_list: D017319:Photosensitizing Agents; D011166:Porphyrins; D026082:Singlet Oxygen; C021096:tetra(4-N-methylpyridyl)porphine