A phage protein confers resistance to the lactococcal abortive infection mechanism AbiP.
Phage bIL66M1 is sensitive to the lactococcal abortive infection mechanism AbiP. No spontaneous AbiP-resistant variant could be obtained at a frequency of <10(-10). However, AbiP-resistant variants were readily obtained during infection with both bIL66M1 and the highly homologous AbiP-resistant phage bIL170. Gain of AbiP resistance was due to the acquisition of the e6 gene from bIL170.
Domingues
Susana
S
Laboratoire de Génétique Microbienne, INRA, 78352 Jouy-en-Josas, France.
Chopin
Alain
A
Ehrlich
S Dusko
SD
Chopin
Marie-Christine
MC
D001426:Bacterial Proteins / Q000502:physiology*; D001435:Bacteriophages / Q000737:chemistry / Q000235:genetics / Q000254:growth & development*; D001483:Base Sequence; D013294:Lactococcus lactis / Q000821:virology*; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D014764:Viral Proteins / Q000502:physiology*
D001426:Bacterial Proteins; D014764:Viral Proteins