title: Supported synthesis of ferrocene modified oligonucleotides as new electroactive DNA probes.
abstract: The use of 1-[3-O-(2-cyanoethyl-N,N-diisopropylphosphor amidityl)propyl]ferrocene and 1-[3-O-dimethoxytrityl propyl]-1'-[3'-O-(2-cyanoethyl-N,N-diisopropylphosphoramidityl) propyl] ferrocene as reactive synthons for DNA/RNA synthesizer allows to generate ferrocene-labelled oligonucleotides with remarkable DNA detection properties.
authors.affiliation: Groupe de Chimie Organique et Matériaux Moléculaires, UMR CNRS 6114, Faculté des Sciences de Luminy, case 901, 163 avenue de Luminy, 13288 Marseille Cedex 9, France.
authors.forename: Aude-Emmanuelle
authors.initials: AE
authors.lastname: Navarro
authors.forename: Nicolas
authors.initials: N
authors.lastname: Spinelli
authors.forename: Carole
authors.initials: C
authors.lastname: Chaix
authors.forename: Corinne
authors.initials: C
authors.lastname: Moustrou
authors.forename: Bernard
authors.initials: B
authors.lastname: Mandrand
authors.forename: Hugues
authors.initials: H
authors.lastname: Brisset
mesh_terms: D000595:Amino Acid Sequence; D015342:DNA Probes / Q000138:chemical synthesis*; D004563:Electrochemistry; D005296:Ferrous Compounds / Q000737:chemistry*; D000075163:Metallocenes; D009693:Nucleic Acid Hybridization; D009841:Oligonucleotides / Q000138:chemical synthesis* / Q000737:chemistry; D009943:Organophosphorus Compounds
chemical_list: D015342:DNA Probes; D005296:Ferrous Compounds; D000075163:Metallocenes; D009841:Oligonucleotides; D009943:Organophosphorus Compounds; C434331:phosphoramidite; C004998:ferrocene