Acquired Glanzmann's thrombasthenia as part of multiple-autoantibody syndrome in a pediatric heart transplant patient.
Although advances in immunosuppressive therapy have allowed prolonged patient survival, immune dysregulation observed in these patients has increased. We report an 11-year-old female heart transplant recipient in whom Glanzmann thrombasthenia was identified as part of a "multiple autoantibody syndrome" manifesting sequentially as autoimmune hemolytic anemia, thrombocytopenia, and neutropenia.
Rawal
Ajay
A
Department of Pathology, UT Southwestern Medical Center, Dallas, Texas 75390, USA.
Sarode
Ravindra
R
Curtis
Brian R
BR
Karandikar
Nitin J
NJ
Friedman
Ken
K
Rogers
Zora R
ZR
D001327:Autoimmune Diseases / Q000139:chemically induced*; D005260:Female; D016027:Heart Transplantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007223:Infant; D013915:Thrombasthenia / Q000139:chemically induced*
D007166:Immunosuppressive Agents