title: Acne in ethnic skin: special considerations for therapy.
abstract: Acne vulgaris occurs in people of all ethnicities and races. Although the pathophysiology and treatment options are similar in all skin phototypes, darker-skinned patients have higher incidence rates of two sequelae of acne: postinflammatory hyperpigmentation and keloidal scarring. Postinflammatory hyperpigmentation may also be triggered by skin irritation. In choosing therapies for patients of color, therefore, clinicians must find a balance between aggressive early intervention to target inflammatory acne lesions, and gentle treatments to increase tolerability and avoid skin irritation. For most patients, a combination of topical retinoids, and topical or oral antibiotics with hydroquinone (as needed) to control hyperpigmentation will be successful. For patients with sensitive skin, topical agents in lower concentrations and cream vehicles are preferred. If tolerated, the retinoid strength can be titrated upward after four to six weeks. Ethnic patients also need to be counseled on use of noncomedogenic and nonirritating skin and hair-care products. Individualized care and close monitoring is required.
authors.affiliation: Department of Dermatology, Howard University College of Medicine, 2041 Georgia Avenue NW, Washington, DC 20060, USA. drcallender@CallenderSkin.com
authors.forename: Valerie D
authors.initials: VD
authors.lastname: Callender
mesh_terms: D000152:Acne Vulgaris / Q000150:complications / Q000188:drug therapy* / Q000235:genetics*; D000279:Administration, Cutaneous; D000284:Administration, Oral; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D006016:Glycolates / Q000008:administration & dosage; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage; D006873:Hydroquinones / Q000008:administration & dosage; D017495:Hyperpigmentation / Q000150:complications / Q000188:drug therapy* / Q000235:genetics*; D007641:Keratolytic Agents / Q000008:administration & dosage; D012176:Retinoids / Q000008:administration & dosage
chemical_list: D000900:Anti-Bacterial Agents; D006016:Glycolates; D006873:Hydroquinones; D007641:Keratolytic Agents; D012176:Retinoids; C031149:glycolic acid; D006820:Hyaluronic Acid