title: Efficacy of sodium hypochlorite and coconut soap used as disinfecting agents in the reduction of denture stomatitis, Streptococcus mutans and Candida albicans.
abstract: This study evaluated the reduction of denture stomatitis and the antimicrobial activity of 0.05% sodium hypochlorite opposed to Candida albicans and Streptococcus mutans (SGM) when associated with brushing complete dentures with coconut soap. The mucosal characteristics were evaluated according to Newton's classification at baseline, after cleansing the dentures with coconut soap for 15 days in group 1 (nine patients). In the other group (19 patients) the analysis were made before and after cleansing the dentures with coconut soap and with disinfection in a soak solution of 0.05% sodium hypochlorite for 10 min during 15 days. Microbiological tests were used to isolate C. albicans and SGM. Mann-Whitney and Wilcoxon tests were used to compare the mucosal characteristics and Fisher test and McNemar test to compare C. albicans and SGM levels. Statistical analysis at the 95% confidence level (P < 0.05) showed that: (i) the association of coconut soap and 0.05% sodium hypochlorite significantly reduced clinical signs of denture stomatitis, (ii) C. albicans did not reduce in counts, (iii) SGM were reduced but not significantly and (iv) the association of coconut soap and 0.5% sodium hypochlorite was effective in controlling denture biofilm.
authors.affiliation: Department of Prosthodontics, Bauru School of Dentistry, University of São Paulo, São Paulo, Brazil. wbarnabe@hotmail.com
authors.forename: W
authors.initials: W
authors.lastname: Barnabé
authors.forename: T
authors.initials: T
authors.lastname: de Mendonça Neto
authors.forename: F C
authors.initials: FC
authors.lastname: Pimenta
authors.forename: L F
authors.initials: LF
authors.lastname: Pegoraro
authors.forename: J M
authors.initials: JM
authors.lastname: Scolaro
mesh_terms: D000368:Aged; D000890:Anti-Infective Agents / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects / Q000254:growth & development / Q000302:isolation & purification; D003059:Cocos; D015169:Colony Count, Microbial; D003820:Denture Cleansers / Q000627:therapeutic use*; D004203:Disinfection / Q000379:methods; D006801:Humans; D008875:Middle Aged; D012915:Soaps; D012973:Sodium Hypochlorite / Q000627:therapeutic use*; D013282:Stomatitis, Denture / Q000382:microbiology / Q000473:pathology / Q000517:prevention & control*; D013295:Streptococcus mutans / Q000187:drug effects / Q000254:growth & development / Q000302:isolation & purification
chemical_list: D000890:Anti-Infective Agents; D003820:Denture Cleansers; D012915:Soaps; D012973:Sodium Hypochlorite