Modeling water vapor and heat transfer in the normal and the intubated airways.
Intubation of the artificially ventilated patient with an endotracheal tube bypasses the usual conditioning regions of the nose and mouth. In this situation any deficit in heat or moisture in the air is compensated for by evaporation and thermal transfer from the pulmonary airway walls. To study the dynamics of heat and water transport in the intubated airway, a coupled system of nonlinear equations is solved in airway models with symmetric geometry and anatomically based geometry. Radial distribution of heat, water vapor, and velocity in the airway are described by power-law equations. Solution of the time-dependent system of equations yields dynamic airstream and mucosal temperatures and air humidity. Comparison of model results with two independent experimental studies in the normal and intubated airway shows a close correlation over a wide range of minute ventilation. Using the anatomically based model a range of spatially distributed temperature paths is demonstrated, which highlights the model's ability to predict thermal behavior in airway regions currently inaccessible to measurement. Accurate representation of conducting airway geometry is shown to be necessary for simulating mouth-breathing at rates between 15 and 100 l x min(-1), but symmetric geometry is adequate for the low minute ventilation and warm inspired air conditions that are generally supplied to the intubated patient.
Tawhai
Merryn H
MH
Bioengineering Institute, The University of Auckland, Auckland, New Zealand. m.tawhai@auckland.ac.nz
Hunter
Peter J
PJ
D003198:Computer Simulation; D004735:Energy Transfer; D006358:Hot Temperature; D006801:Humans; D006813:Humidity; D007442:Intubation, Intratracheal; D008954:Models, Biological; D012123:Pulmonary Ventilation; D012121:Respiration, Artificial; D012143:Respiratory Physiological Phenomena; D013696:Temperature; D014132:Trachea / Q000033:anatomy & histology / Q000502:physiology; D014835:Volatilization; D014867:Water
D014867:Water