Cyclic lymphocytic vasculitis associated with chronic lymphocytic leukemia.
Lymphocytic cutaneous vasculitis associated with a haematological malignancy has rarely been reported. Here, we describe a 61 year-old woman with chronic lymphocytic leukemia (CLL) who presented with cutaneous lesions on both hands. These lesions improved after all combination chemotherapy courses and recurred before each course. Repetitive skin biopsies revealed lymphocytic vasculitis. After 7 courses of chemotherapy, she had a complete remission. Skin lesions disappeared and did not recur. The cyclic pattern of lymphocytic vasculitis and its relation with CLL disease activity are interesting clinical features in this case.
Cabuk
Mine
M
Department of Haematology, Celal Bayar University, Manisa, Turkey. minecabuk@hotmail.com
Inanir
Işil
I
Türkdoğan
Peyker
P
Ceylan
Cengiz
C
Değirmenci
Mustafa
M
Türel
Aylin
A
Ozdemir
Ertan
E
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000188:drug therapy; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000209:etiology; D012074:Remission Induction; D017445:Skin Diseases, Vascular / Q000209:etiology; D013601:T-Lymphocytes / Q000473:pathology; D014657:Vasculitis / Q000209:etiology*