title: Toxic shock syndrome.
abstract: The authors present two children who had fever >or=38.9 degree C, diffuse rash, hypotension, deranged renal and hepatic functions, disseminated intravascular coagulation, altered sensorium and inflamed oral mucosa. They responded to fluids, inotropes, antibiotics and intravenous immunoglobulin (2 g/kg). Desquamation particularly of palms and soles and periungal region was noted 1 to 2 weeks after onset of illness. These features were consistent with the diagnosis of staphylococcal toxic shock syndrome (TSS). The cases highlight that TSS is very much with us and can mimic a variety of other diseases. Early recognition, and aggressive antimicrobial supportive and IVIG therapy cover can ensure complete recovery.
authors.affiliation: Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
authors.forename: Rashna
authors.initials: R
authors.lastname: Dass
authors.forename: P
authors.initials: P
authors.lastname: Nishad
authors.forename: Sunit
authors.initials: S
authors.lastname: Singhi
mesh_terms: D000900:Anti-Bacterial Agents; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004322:Drainage / Q000379:methods; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D005440:Fluid Therapy; D005500:Follow-Up Studies; D006801:Humans; D015278:Intensive Care Units, Pediatric; D008297:Male; D018570:Risk Assessment; D012772:Shock, Septic / Q000175:diagnosis* / Q000628:therapy*; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000628:therapy; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents