title: Oxazolidinone: search for highly potent antibacterial.
abstract: A number of substituted piperazinyl oxazolidinone derivatives have been synthesized and their antibacterial activities were evaluated by MIC determination. A systematic SAR was carried out to get highly potent oxazolidinone derivatives.
authors.affiliation: Medicinal Chemistry Department, Zydus Research Centre, Cadila Healthcare Ltd, Sarkhej-Bavla N. H.8A, Moraiya, Ahmedabad 382210, India. braj.lohray@zyduscadila.com
authors.forename: Braj Bhushan
authors.initials: BB
authors.lastname: Lohray
authors.forename: Vidya Bhushan
authors.initials: VB
authors.lastname: Lohray
authors.forename: Brijesh Kumar
authors.initials: BK
authors.lastname: Srivastava
authors.forename: Sunil
authors.initials: S
authors.lastname: Gupta
authors.forename: Manish
authors.initials: M
authors.lastname: Solanki
authors.forename: Prashant
authors.initials: P
authors.lastname: Kapadnis
authors.forename: Vijay
authors.initials: V
authors.lastname: Takale
authors.forename: Purvi
authors.initials: P
authors.lastname: Pandya
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests / Q000706:statistics & numerical data; D023303:Oxazolidinones / Q000138:chemical synthesis* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D023303:Oxazolidinones