Management of sarcomas of the head and neck.
Soft tissue and bone sarcomas in the head and neck are rare tumors. The 1000 to 1500 yearly cases in the United States are distributed among at least 10 main histologies and multiple head and neck subsites. Although this makes structured studies difficult to perform and high-level evidence-based treatment algorithms difficult to find, basic treatment recommendations can be made from the existing literature for most histologies and subsites. This paper discusses the epidemiology, natural history, and treatment approaches for several of the most common head and neck sarcomas, including the "adult soft tissue sarcomas," osteosarcoma, chondrosarcoma of the larynx, angiosarcoma, rhabdomyosarcoma, desmoid tumors, and dermatofibrosarcoma protuberans.
Brockstein
Bruce
B
Feinberg School of Medicine, Northwestern University, Evanston Northwestern Healthcare, 2650 Ridge Avenue, Evanston, IL 60201, USA. b-brockstein@northwestern.edu
D002813:Chondrosarcoma / Q000601:surgery; D018223:Dermatofibrosarcoma / Q000601:surgery; D018222:Desmoid Tumors / Q000601:surgery; D006258:Head and Neck Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D006394:Hemangiosarcoma / Q000601:surgery; D006801:Humans; D015994:Incidence; D033183:Interdisciplinary Communication; D012516:Osteosarcoma / Q000601:surgery; D011379:Prognosis; D012208:Rhabdomyosarcoma / Q000601:surgery; D012509:Sarcoma / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D012983:Soft Tissue Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology