title: [Detection of high-sensitivity C-reactive protein and total cholesterol/high-density lipoprotein cholesterol ratio for diagnosis of coronary artery disease].
abstract: OBJECTIVE
  To study the value of detecting high-sensitivity C-reactive protein (hs-CRP) combined with determination of total cholesterol/high-density lipoprotein cholesterol (TC/HDL-C) in the diagnosis of coronary artery disease (CHD).
  
  
  METHODS
  A total of 240 patients with documented CHD and 40 healthy subjects were enrolled in this study for measurement of serum concentrations of hs-CRP, TC and HDL-C.
  
  
  RESULTS
  The concentration of hs-CRP and TC/HDL-C ratio was significantly higher in CHD patients than in the control subjects (P<0.01). The positivity rate by detecting both the two markers (0.950) was higher than that of single marker detection of either hs-CRP (0.850) or TC/HDL-C (vs 0.767).
  
  
  CONCLUSIONS
  Detection of hs-CRP combined with determination of TC/HDL-C may facilitate early diagnosis of CHD.
authors.affiliation: Department of Clinical Laboratory, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China.
authors.forename: Chao-xin
authors.initials: CX
authors.lastname: Jiang
authors.forename: Zhi-liang
authors.initials: ZL
authors.lastname: Li
authors.forename: Quan-neng
authors.initials: QN
authors.lastname: Yan
mesh_terms: D000368:Aged; D002097:C-Reactive Protein / Q000032:analysis*; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood*; D003324:Coronary Artery Disease / Q000097:blood / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D008076:Cholesterol, HDL; D002097:C-Reactive Protein; D002784:Cholesterol