Evaluation of isoproterenol in patients undergoing resuscitation for out-of-hospital asystolic cardiac arrest (the Israel Resuscitation with Isoproterenol Study Prospective Randomized Clinical Trial).
The Israel Resuscitation with Isoproterenol Study included 79 consecutive patients with witnessed out-of-hospital asystolic cardiac arrest who were resuscitated with epinephrine and atropine and randomized to receive additional isoproterenol or no isoproterenol. The rate of return of spontaneous circulation and survival to hospital admission did not differ in patients receiving standard therapy and those receiving additional isoproterenol.
Jaffe
Ronen
R
The Lady Davis Carmel Medical Center, 7 Michal Street, Haifa 34362, Israel. jaffe@clalit.org
Rubinshtein
Ronen
R
Feigenberg
Zvi
Z
Talor
Eran
E
Michaelson
Moshe
M
Karkabi
Basheer
B
Halon
David A
DA
Flugelman
Moshe Y
MY
Lewis
Basil S
BS
D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D000368:Aged; D001285:Atropine / Q000627:therapeutic use; D004837:Epinephrine / Q000627:therapeutic use; D005260:Female; D006323:Heart Arrest / Q000401:mortality / Q000628:therapy*; D006801:Humans; D007545:Isoproterenol / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012151:Resuscitation
D000318:Adrenergic beta-Agonists; D001285:Atropine; D007545:Isoproterenol; D004837:Epinephrine