title: Routine use of gradient-echo MRI to screen for cerebral amyloid angiopathy in elderly patients.
abstract: OBJECTIVE
  The objective of this study was to evaluate the routine use of gradient-refocused echo MRI sequences in the detection of cortical cerebral microbleeding suggestive of cerebral amyloid angiopathy in elderly patients (> 70 years old).
  
  
  CONCLUSIONS
  The addition of gradient-refocused echo sequences to routine brain MRI resulted in the identification of cerebral amyloid angiopathy-related microbleeding in 15.5% of elderly patients. In most (86.7%) of these patients with positive findings, cerebral amyloid angiopathy was not suspected clinically, and 46.7% of these patients were undergoing anticoagulant or aspirin therapy, placing them at an increased risk of recurrent intracranial hemorrhage and catastrophic stroke.
authors.affiliation: Department of Radiology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224-1865, USA.
authors.forename: D A
authors.initials: DA
authors.lastname: Walker
authors.forename: D F
authors.initials: DF
authors.lastname: Broderick
authors.forename: A L
authors.initials: AL
authors.lastname: Kotsenas
authors.forename: F A
authors.initials: FA
authors.lastname: Rubino
mesh_terms: D000368:Aged; D016657:Cerebral Amyloid Angiopathy / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male