Impact of major side branch on periprocedural enzyme elevation and long-term outcome in patients undergoing percutaneous coronary intervention and brachytherapy for in-stent restenosis.
Side branch occlusion is 1 mechanism for the increase of creatine phosphokinase-MB after percutaneous coronary intervention and is associated with long-term adverse events. We studied 248 patients who underwent brachytherapy for in-stent restenosis with and without side branches, compared levels of creatine phosphokinase-MB with procedural, in-hospital, and long-term clinical outcomes, and found that patients with side branches have increased levels of creatine phosphokinase-MB after percutaneous coronary intervention and higher rates of restenosis, target vessel, and target lesion revascularization at 6-month follow-up.
Kuchulakanti
Pramod
P
Division of Cardiology, Washington Hospital Center, 110 Irving Street NW, Washington, DC 20010, USA.
Rha
Seung-Woon
SW
Satler
Lowell F
LF
Suddath
William O
WO
Pichard
Augusto D
AD
Kent
Kenneth M
KM
Pakala
Rajbabu
R
Canos
Daniel A
DA
Pinnow
Ellen E
EE
Waksman
Ron
R
D015906:Angioplasty, Balloon, Coronary; D001918:Brachytherapy; D003097:Collateral Circulation; D023903:Coronary Restenosis / Q000532:radiotherapy* / Q000628:therapy*; D003402:Creatine Kinase / Q000378:metabolism*; D052279:Creatine Kinase, MB Form; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome
D007527:Isoenzymes; D003402:Creatine Kinase; D052279:Creatine Kinase, MB Form