[Adrenomedullin in cardiovascular pathology].
Adrenomedullin (AM), inducing a potent and powerful hypotensive activity caused by dilatation of resistance vessels, has elicited interest for its cardiovascular actions. AM is secreted from various cell type, including vascular endothelial and smooth muscle cell. AM plasma levels are increased in various cardiovascular diseases as heart failure and hypertension and may be involved in pathophysiological changes in cardiovascular diseases.
Piroli
Emanuela
E
V Clinica Medica, Dipartimento di Fisiopatologia Medica, Policlinico Umberto I, Università La Sapienza, Roma.
Annoscia
Claudia
C
Ranieri
Francesco
F
Priori
Francesca
F
Rossi
Fabio
F
Santiemma
Vittorio
V
D053607:Adrenomedullin; D000818:Animals; D002318:Cardiovascular Diseases / Q000097:blood* / Q000503:physiopathology; D002908:Chronic Disease; D005921:Glomerulonephritis / Q000097:blood / Q000503:physiopathology; D006333:Heart Failure / Q000097:blood / Q000503:physiopathology; D006706:Homeostasis; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000503:physiopathology; D006976:Hypertension, Pulmonary / Q000097:blood / Q000503:physiopathology; D009203:Myocardial Infarction / Q000097:blood / Q000503:physiopathology; D010455:Peptides / Q000008:administration & dosage / Q000097:blood / Q000235:genetics / Q000494:pharmacology / Q000502:physiology; D051381:Rats; D012772:Shock, Septic / Q000097:blood / Q000503:physiopathology
D010455:Peptides; D053607:Adrenomedullin