[Exploration on the relationship between positive antisperm antibody and nitric oxide level of infertile patients and on integrative Chinese and Western medicine treatment].
OBJECTIVE
To study the relationship between the positive antisperm antibody (AsAb) and nitric oxide (NO) content in blood of infertile patients and the therapeutic effect of integrative Chinese and western medicine (ICWM) treatment on the disease.


METHODS
Infertile patients, 75 of AsAb positive and 68 of AsAb negative were selected to observe the mature partuient rate and abortion rate. Serum NO level were measured before treatment to observe the relationship between NO and positive AsAb. Patients were treated with ICWM and followed-up for five years.


RESULTS
Mean value of serum NO in patients with positive AsAb was significantly higher than that in fertile women, and there was no significant difference between patients with negative AsAb and fertile women (P < 0.01). In the 5 years after treatment, the mature partuient rate between the two groups showed insignificant difference (P > 0.05).


CONCLUSIONS
AsAb positive and NO level abnormal may interfere mutually, to intervent the reproductive process. ICWM therapy could effectively regulate auto-immunity and endocrine function, and make the infertile patients obtain satisfactory efficacy.
Liao
Ding-ling
DL
Second Affiliated Hospital of Jiangxi Medical College, Nanchang 330006.
Yu
Li-qun
LQ
Xin
Hua
H
D000328:Adult; D000906:Antibodies / Q000097:blood*; D003907:Dexamethasone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use; D006801:Humans; D007247:Infertility, Female / Q000097:blood / Q000188:drug therapy* / Q000276:immunology; D008297:Male; D009569:Nitric Oxide / Q000097:blood*; D008517:Phytotherapy; D013094:Spermatozoa / Q000276:immunology*
D000906:Antibodies; D004365:Drugs, Chinese Herbal; D005300:Fertility Agents, Female; D009569:Nitric Oxide; D003907:Dexamethasone