[Expression of water channel protein 1 in the lung of the drown rat].
OBJECTIVE
To determine the expression of water channel 1 protein in the lung of drown rat and that of after death thrown into the water.


METHODS
Immunohistochemical method was used and the computer image analysis was conducted to detect the distribution of AQP1.


RESULTS
The positive expression of AQP1 was seen in the capillary endotheliocyte of the interstitial and around bronchi and in the alveolar endothelial cells. The value of intergrated optical density was statistical significant.


CONCLUSIONS
It suggests that AQP1 is one of sensitive signs to distinguish ante-mortem and postmortem immersion.
Hu
Hua-zi
HZ
West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
Yang
Chen
C
Zhi-gang
Liao
L
D000818:Animals; D051398:Aquaporin 1; D020346:Aquaporins / Q000032:analysis / Q000378:metabolism*; D004332:Drowning / Q000378:metabolism*; D042783:Endothelial Cells / Q000378:metabolism; D007150:Immunohistochemistry; D008168:Lung / Q000378:metabolism*; D008565:Membrane Proteins / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley
C496022:Aqp1 protein, rat; D020346:Aquaporins; D008565:Membrane Proteins; D051398:Aquaporin 1