title: [Autism and pervasive developmental disorders].
abstract: OBJECTIVE
  To review the current knowledge on neurobiological aspects of autism and pervasive developmental disorders, as well as to provide pediatricians with up to date information on diagnosis and treatment of autism.
  
  
  METHODS
  Review of MEDLINE and Internet.
  
  
  RESULTS
  Autism is the 3rd developmental disorder, with an incidence of 40 to 130/100,000 individuals. Diagnosis is based on clinical findings, following DSM IV criteria. Neuroimaging, investigation of fetal neurological status, and genetic investigation contribute towards a better understanding of the neurobiology of autism.
  
  
  CONCLUSIONS
  Pediatricians are the first health professional to come in contact with patients with autism. Thus, they should be able to diagnose and to coordinate the multidisciplinary treatment of these patients.
authors.affiliation: Miami Children's Hospital, USA.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Gadia
authors.forename: Roberto
authors.initials: R
authors.lastname: Tuchman
authors.forename: Newra T
authors.initials: NT
authors.lastname: Rotta
mesh_terms: D001321:Autistic Disorder / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy; D002648:Child; D006801:Humans; D011379:Prognosis