title: Epithelioid hemangioendothelioma of the infundibular-hypothalamic region: case report and literature review.
abstract: Epithelioid hemangioendothelioma (EHE) is an uncommon vascular neoplasm. Its intracranial occurrence is rare, and the literature review revealed only 23 cases (14 adults and 9 children). To our knowledge, this is the first case of EHE arising in the infundibular-hypothalamic region. A 53-year-old man presented with headaches and loss of libido. Magnetic resonance imaging revealed a supra-sellar mass, which homogeneously absorbed the contrast agent. A trans-sphenoidal craniotomy and a biopsy were performed. Adjuvant radiotherapy was administered due to intolerance to interferon. Epithelioid hemangioendothelioma is a hemorrhagic tumor. Total resection is mandatory where possible, otherwise radiotherapy seems necessary. The prognosis of intracranial location has not yet been well defined, despite the favorable outcome noted in the majority of cases.
authors.affiliation: Department of Neurosurgery, CHRU Pontchaillou, Rennes, France. hamlat.abd@wanadoo.fr
authors.forename: Abderrahmane
authors.initials: A
authors.lastname: Hamlat
authors.forename: Carlos
authors.initials: C
authors.lastname: Casallo-Quilliano
authors.forename: Stephan
authors.initials: S
authors.lastname: Saikali
authors.forename: Thierry
authors.initials: T
authors.lastname: Lesimple
authors.forename: Gilles
authors.initials: G
authors.lastname: Brassier
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000628:therapy; D018323:Hemangioendothelioma, Epithelioid / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007031:Hypothalamus / Q000473:pathology*; D007124:Immunoenzyme Techniques; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000737:chemistry / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography
chemical_list: D014408:Biomarkers, Tumor