title: Determination of (+)-3,3',5-triiodo-L-thyronine (L-T3) from serum using a sequential injection analysis/immunosensor system.
abstract: A sequential injection analysis/immunosensor system is proposed for the analysis of T3 in serum with a rate of 75 samples/hr. The immunosensor design is based on the physical immobilization of anti-T3 in carbon paste. The working concentration range of the immunosensor in a sequential injection analysis system is between 3.4 and 340 ng/mL with a limit of detection of 2.19 ng/mL. The system is very reliable and very easy to design and operate.
authors.affiliation: Department of Chemistry, University of Pretoria, Pretoria, South Africa. raluca.stefan@chem.up.ac.za
authors.forename: Raluca-Ioana
authors.initials: RI
authors.lastname: Stefan
authors.forename: Jacobus Frederick
authors.initials: JF
authors.lastname: van Staden
authors.forename: Hassan Y
authors.initials: HY
authors.lastname: Aboul-Enein
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D004563:Electrochemistry; D017022:Flow Injection Analysis / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014284:Triiodothyronine / Q000097:blood*
chemical_list: D014284:Triiodothyronine