Fetal ultrasonography to prevent irreversible neurological sequelae of neonatal neuroblastoma.
An intra-abdominal mass was observed by fetal ultrasonography at 32 weeks of gestation. The baby was diagnosed as having neuroblastoma at the time of delivery at 39 weeks and its lower extremities were completely paralyzed. The chemotherapy after birth was quite effective to reduce the mass volume but neurological sequelae failed to improve. By carefully monitoring the movement of extremities, it may have been possible to prevent irreversible by inducing delivery before that state was reached.
Nagasako
Hironobu
H
Department of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima City 890-8520, Japan.
Ijichi
Osamu
O
Shinkoda
Yuichi
Y
Ikarimoto
Naoaki
N
Kaji
Tatsuri
T
Nakame
Kazuhiko
K
Takamatsu
Hideo
H
Kawano
Yoshifumi
Y
D000970:Antineoplastic Agents / Q000627:therapeutic use; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging; D006801:Humans; D007231:Infant, Newborn; D035002:Lower Extremity / Q000503:physiopathology; D009422:Nervous System Diseases; D009447:Neuroblastoma / Q000150:complications* / Q000000981:diagnostic imaging* / Q000188:drug therapy; D010243:Paralysis / Q000196:embryology / Q000209:etiology* / Q000517:prevention & control; D011247:Pregnancy; D013117:Spinal Cord Compression / Q000196:embryology / Q000209:etiology / Q000517:prevention & control; D016216:Ultrasonography, Prenatal
D000970:Antineoplastic Agents