title: Regional wall motion and wall thickening visual scores from gated SPECT in anterior and infero-lateral myocardial infarctions.
abstract: BACKGROUND
  The relationship between the visual scores for wall motion (WM) and wall thickening (WT) of different left ventricular regions in patients with anterior and infero-lateral myocardial infarctions was evaluated using gated SPECT.
  
  
  METHODS
  Ninety consecutive patients (79 men and 11 women; mean age 56 +/- 9 years) with previous myocardial infarction (33 anterior and 57 infero-lateral) were included. Left ventricular volumes and ejection fractions (EFs) were calculated from quantitative rest gated SPECT 99mTc tetrofosmin images by using the QGS automatic algorithm. Global and regional (anterior, septal, inferior and lateral) wall motion and wall thickening scores were calculated by consensus of three experienced observers.
  
  
  RESULTS
  The correlation between EFs and wall motion and wall thickening scores was better for WM scores in anterior (r=0.904, P<0.0001) than infero-lateral infarctions (r=0.674, P<0.0001). Correlation between wall motion and wall thickening scores was also better for anterior (r=0.898, P<0.0001) than for infero-lateral infarctions (r=0.750, P<0.0001). Except in septal regions, WT scores of the different regions were higher than WM scores (P<0.05) but the statistical significance was higher (P<0.001) in inferior and lateral regions of infero-lateral infarctions.
  
  
  CONCLUSIONS
  Visual global wall motion and wall thickening scores obtained by gated SPECT showed good correlation between them and with the EF, but differences were observed between regional wall motion and wall thickening, especially in inferior and lateral regions of patients with infero-lateral infarctions.
authors.affiliation: Servei de Cardiologia, Hospital General Universitari Vall d'Hebron, Pg. Vall d'Hebron 119-129, 08035 Barcelona, Spain. jcandell@vhebron.net
authors.forename: Jaume
authors.initials: J
authors.lastname: Candell-Riera
authors.forename: Osvaldo
authors.initials: O
authors.lastname: Pereztol-Valdés
authors.forename: Santiago
authors.initials: S
authors.lastname: Aguadé-Bruix
authors.forename: Joan
authors.initials: J
authors.lastname: Castell-Conesa
authors.forename: Guillermo
authors.initials: G
authors.lastname: Oiler-Martínez
authors.forename: Marc
authors.initials: M
authors.lastname: Simó
authors.forename: Marina
authors.initials: M
authors.lastname: Soler-Peter
authors.forename: Antoni
authors.initials: A
authors.lastname: Rubió
authors.forename: Jordi
authors.initials: J
authors.lastname: Soler-Soler
mesh_terms: D000368:Aged; D004562:Electrocardiography / Q000187:drug effects; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology; D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D013318:Stroke Volume; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C078700:technetium tc-99m tetrofosmin