title: Cost study of metal stent placement vs single-dose brachytherapy in the palliative treatment of oesophageal cancer.
abstract: Self-expanding metal stent placement and single-dose brachytherapy are commonly used for the palliation of oesophageal obstruction due to inoperable oesophagogastric cancer. We randomised 209 patients to the placement of an Ultraflex stent (n=108) or single-dose brachytherapy (12 Gy, n=101). Cost comparisons included comprehensive data of hospital costs, diagnostic interventions and extramural care. We acquired detailed information on health care consumption from a case record form and from monthly home visits by a specialised nurse. The initial costs of stent placement were higher than the costs of brachytherapy (1500 euro vs 570 euro; P<0.001). Total medical costs were, however, similar (stent 11 195 euro vs brachytherapy 10 078 euro, P>0.20). Total hospital stay during follow-up was 11.5 days after stent placement vs 12.4 days after brachytherapy, which was responsible for the high intramural costs in both treatment groups (stent 6512 euro vs brachytherapy 7982 euro, P>0.20). Costs for medical procedures during follow-up were higher after stent placement (stent 249 euro vs brachytherapy 168 euro, P=0.002), while the costs of extramural care were similar (1278 euro vs 1046 euro, P>0.20). In conclusion, there are only small differences between the total medical costs of both palliative treatment modalities, despite the fact that the initial costs of stent placement are much higher than those of brachytherapy. Therefore, cost considerations should not play an important role in decision making on the appropriate palliative treatment strategy for patients with malignant dysphagia.
authors.affiliation: Department of Public Health, Erasmus MC/University Medical Center Rotterdam, PO Box 1738, 3000 CA Rotterdam, The Netherlands. s.polinder@erasmusmc.nl
authors.forename: S
authors.initials: S
authors.lastname: Polinder
authors.forename: M Y V
authors.initials: MY
authors.lastname: Homs
authors.forename: P D
authors.initials: PD
authors.lastname: Siersema
authors.forename: E W
authors.initials: EW
authors.lastname: Steyerberg
mesh_terms: D000368:Aged; D001918:Brachytherapy / Q000191:economics* / Q000379:methods*; D003365:Costs and Cost Analysis; D004938:Esophageal Neoplasms / Q000150:complications* / Q000532:radiotherapy*; D004940:Esophageal Stenosis / Q000209:etiology* / Q000628:therapy; D005260:Female; D017048:Health Care Costs / Q000706:statistics & numerical data*; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010166:Palliative Care / Q000191:economics*; D015607:Stents / Q000191:economics