title: Massive endolymphatic sac and vestibular aqueduct in Mondini dysplasia.
abstract: A postmortem study was performed on the bilateral temporal bones of a 90-year-old woman who had a lifelong profound hearing impairment. The histopathologic findings included severe Mondini dysplasia with unusual enlargement of the vestibular aqueducts and endolymphatic sacs. Dehiscent carotid arteries and dehiscent facial nerves were also present. The clinical and surgical aspects of the case are discussed based on the histopathologic findings. The physician should be prepared to diagnose congenital hearing impairment promptly to avoid complications during the clinical and surgical treatment of patients with Mondini dysplasia.
authors.affiliation: International Hearing Foundation, Minneapolis, MN, USA.
authors.forename: Andre L L
authors.initials: AL
authors.lastname: Sampaio
authors.forename: Sebahattin
authors.initials: S
authors.lastname: Cureoglu
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Schachern
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kusunoki
authors.forename: Michael M
authors.initials: MM
authors.lastname: Paparella
authors.forename: Carlos A C P
authors.initials: CA
authors.lastname: Oliveira
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004712:Endolymphatic Sac / Q000473:pathology*; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000473:pathology*; D006801:Humans; D013701:Temporal Bone / Q000473:pathology*; D014723:Vestibular Aqueduct / Q000473:pathology*