Recalcitrant adverse reaction to vitamin K: response to pulsed dye laser.
BACKGROUND
Adverse cutaneous reaction to vitamin K manifests in sclerodermatous or erythematous plaque-like reactions. Most of the cases with erythematous plaque-like dermatitis arising at the site of intramuscular vitamin K injection were recalcitrant and did not respond to various attempts with topical and intralesional corticosteroid.


OBJECTIVE
The objective was to describe a 25-year-old woman with recalcitrant adverse reaction owing to vitamin K who was successfully treated with pulsed dye laser.


METHODS
Two consecutive pulsed dye laser treatments were performed 3 weeks apart with 450-microec pulse duration, 585-nm pulse width, and fluence of 5 and 7 J/cm(2), respectively, using a 7-mm handpiece.


RESULTS
One week after the second treatment, her skin lesion was cleared and she was followed without recurrence for 7 months.


CONCLUSIONS
Although the precise mechanism remains yet to be proven, we have demonstrated successful treatment of localized adverse cutaneous reaction to vitamin K in one patient with the pulsed dye laser.
Jung
Jeanne
J
Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Cho
Sung Bin
SB
Chung
Kee Yang
KY
D000328:Adult; D002081:Buttocks; D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D028022:Low-Level Light Therapy; D012008:Recurrence; D014812:Vitamin K / Q000008:administration & dosage / Q000009:adverse effects*
D014812:Vitamin K