title: Insect antifeedants from tropical plants: structures of dumnin and dumsenin.
abstract: Two novel A-seco limonoids, dumnin and dumsenin, were isolated from the methanolic extract of Croton jatrophoides by bioassay-guided fractionation, and the structures were determined by nuclear magnetic resonance, circular dichroism, and mass spectrometry experiments. These compounds showed potent antifeedant activity (PC(50) <or= 2.0 microg/mL) against the larvae of pink bollworm, Pectinophora gossypiella, and/or fall armyworm, Spodoptera frugiperda, providing results comparable to dumsin and zumsin, previously isolated from the same plant.
authors.affiliation: Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720-3112, USA.
authors.forename: Ken-Ichi
authors.initials: K
authors.lastname: Nihei
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Asaka
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Mine
authors.forename: Chihiro
authors.initials: C
authors.lastname: Ito
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Furukawa
authors.forename: Motoharu
authors.initials: M
authors.lastname: Ju-Ichi
authors.forename: Isao
authors.initials: I
authors.lastname: Kubo
mesh_terms: D000818:Animals; D002942:Circular Dichroism; D029802:Croton / Q000737:chemistry*; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification; D007814:Larva; D036701:Limonins / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D000432:Methanol; D015394:Molecular Structure; D009036:Moths; D010936:Plant Extracts / Q000737:chemistry; D018411:Spodoptera
chemical_list: D007306:Insecticides; D036701:Limonins; D010936:Plant Extracts; C487582:dumnin; C487583:dumsenin; D000432:Methanol