Effects of long-term prednisone (> or =5 mg) use on outcomes and complications of percutaneous coronary intervention.
To assess the potential risk of long-term steroid use in the setting of coronary angioplasty, 114 patients of 12,883 consecutively treated patients who were on long-term steroids were compared with those not taking steroids. Steroid use was not associated with increased risk of composite major ischemia events but was associated with a threefold risk (p = 0.01) of major vascular complications and a three- to fourfold risk (p = 0.026) of coronary perforation.
Ellis
Stephen G
SG
Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, 9500 Euclid Avenue, F-25, Cleveland, OH 44195, USA. elliss@ccf.org
Semenec
Terance
T
Lander
Katherine
K
Franco
Irving
I
Raymond
Russell
R
Whitlow
Patrick L
PL
D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects; D016022:Case-Control Studies; D003331:Coronary Vessels / Q000293:injuries; D016208:Databases, Factual; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000009:adverse effects / Q000627:therapeutic use*; D012306:Risk; D013997:Time Factors; D016896:Treatment Outcome
D005938:Glucocorticoids; D011241:Prednisone