Long lasting effects of transcranial direct current stimulation on motor imagery.
Transcranial magnetic stimulation (TMS) was employed to probe the modulatory effects of transcranial direct current stimulation of motor cortex on motor evoked responses (MEPs) produced during motor imagery. MEP amplitudes at rest and during motor imagery were assessed before and for a period of 60 min after transcranial direct current stimulation (tDCS) applied over the primary motor cortex at 1 mA for 5 min. Cathodal stimulation induced a decrease of about 30% of MEP amplitude at rest and a 50% reduction of MEP size during imagery. Ten minutes after tDCS, MEPs at rest returned to baseline values while MEPs during motor imagery were suppressed for up to 30 min. No changes in MEP amplitude during imagery were found after anodal stimulation. tDCS could represent a powerful tool to modulate the excitability of motor areas involved in mental practice and motor imagery.
Quartarone
Angelo
A
Department of Neurosciences, Psychiatric and Anaesthesiological Sciences, Clinica Neurologica 2, Policlinico Universitario, 98125 Messina, Italy. angelo.quartarone@unime.it
Morgante
Francesca
F
Bagnato
Sergio
S
Rizzo
Vincenzo
V
Sant'Angelo
Antonino
A
Aiello
Elena
E
Reggio
Ester
E
Battaglia
Fortunato
F
Messina
Corrado
C
Girlanda
Paolo
P
D000328:Adult; D003071:Cognition / Q000502:physiology; D004558:Electric Stimulation / Q000379:methods; D004574:Electromagnetic Fields; D019054:Evoked Potentials, Motor / Q000502:physiology*; D005260:Female; D005385:Fingers / Q000294:innervation / Q000502:physiology; D006801:Humans; D007092:Imagination / Q000502:physiology*; D008280:Magnetics; D008297:Male; D009044:Motor Cortex / Q000502:physiology*; D009068:Movement / Q000502:physiology*; D009415:Nerve Net / Q000033:anatomy & histology / Q000502:physiology; D009434:Neural Pathways / Q000033:anatomy & histology / Q000502:physiology; D009483:Neuropsychological Tests; D011930:Reaction Time / Q000502:physiology