title: Soy-induced brain atrophy?
abstract: Epidemiological research has demonstrated a positive correlation between tofu consumption and brain atrophy in men. Because correlation does not prove causation, correlation-based hypotheses should be tested against the availability of possible causal mechanisms. While it has been shown that the soy phytoestrogen genistein inhibits neuroprotective functions in cell cultures, recent in-vivo findings strengthen the case for a possible causal mechanism of soy-induced neurodegeneration. The author suggests possible responses to this data regarding soy consumption.
authors.affiliation: University of Maryland, College Park, Maryland, USA. igoddard@umd.edu
authors.forename: Ian Williams
authors.initials: IW
authors.lastname: Goddard
mesh_terms: D001284:Atrophy / Q000209:etiology; D001921:Brain / Q000473:pathology*; D006801:Humans; D008297:Male; D045730:Soy Foods / Q000009:adverse effects*