[82-year old patient with hyperostosis frontalis, prognathism, makroglossia and cutis gyrata. Acromegaly].
We present a 82 year old female patient with typical acral enlargement. There were no signs of visceromegaly. Magnetic resonance imaging of the pituitary region showed a macroadenoma. Oral glucose tolerance test revealed missing suppression of the Human Growth Hormone (HGH), which could be achieved with a long acting somatostatin analog. A HGH suppressive therapy with a long acting dopamine agonist (Cabergolin) was induced. The patient died one year later following cardiovascular complications.
Mönnich
H
H
Abteilung Innere Medizin I, Sektion Endokrinologie, Universitätsklinikum Ulm.
Böhm
B O
BO
Weidenbach
H
H
D000172:Acromegaly / Q000175:diagnosis*; D000236:Adenoma / Q000175:diagnosis; D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006957:Hyperostosis Frontalis Interna / Q000209:etiology*; D008260:Macroglossia / Q000209:etiology*; D010911:Pituitary Neoplasms / Q000175:diagnosis; D011378:Prognathism / Q000209:etiology*