title: Basic epidemiology of inflammatory bowel disease in Puerto Rico.
abstract: BACKGROUND
  Previous epidemiological studies have suggested that the incidence of inflammatory bowel disease (IBD) is lower in Latin American populations. The aim of this study was to estimate the incidence of IBD in Puerto Rico, a predominantly Hispanic population.
  
  
  METHODS
  A nonconcurrent prospective study was conducted in collaboration with private gastroenterologists in southwest Puerto Rico. Basic medical history and demographics were extracted from the medical records of patients for which a new diagnosis of IBD (Crohn's disease, CD; ulcerative colitis, UC; or nonspecified IBD) was made during each of the years 1996-2000.
  
  
  RESULTS
  A total of 202 eligible cases of IBD were identified (95 male, 107 female). Forty-eight patients were diagnosed with CD, 102 with UC, and 52 with nonspecified IBD. The total incidence of IBD increased significantly between 1996 and 2000 (3.07/100,000 to 7.74/100,000; p < 0.001), being significantly higher for CD (four-fold increase, p < 0.01) and nonspecified IBD (fourfold increase, p < 0.005), but not UC (1.7-fold increase). The prevalence of CD was higher in males with an earlier age of onset (p < 0.05).
  
  
  CONCLUSIONS
  This study demonstrates that the incidence of IBD within the Puerto Rican population is increasing and may be higher than previously reported for other Latin American populations.
authors.affiliation: Department of Physiology, Biostatistics Core Program, Ponce School of Medicine, Ponce, Puerto Rico. cappleyard@psm.edu
authors.forename: Caroline B
authors.initials: CB
authors.lastname: Appleyard
authors.forename: Gerardo
authors.initials: G
authors.lastname: Hernández
authors.forename: Carlos F
authors.initials: CF
authors.lastname: Rios-Bedoya
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D015331:Cohort Studies; D003093:Colitis, Ulcerative / Q000175:diagnosis* / Q000453:epidemiology*; D003424:Crohn Disease / Q000175:diagnosis* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011336:Probability; D011379:Prognosis; D011446:Prospective Studies; D011647:Puerto Rico / Q000453:epidemiology; D018570:Risk Assessment; D012720:Severity of Illness Index; D017678:Sex Distribution