title: [Mycoplasma infection and cancer].
abstract: Mycoplasmas are widespread in nature as conditional pathogen, which may be the unique prokaryote that can cohabit with eukaryote and interact permanently with mammalian cells. Mycoplasma infection can be detected in many tumor tissues, continuous infection of mycoplasma can lead to transformation of mammalian cells, up-regulating expression of oncogenes, and some biologic changes of tumor cells, suggesting association of mycoplasma infection with tumorigenesis.
authors.affiliation: Department of Biochemistry and Molecular Biology, Beijing Institute for Cancer Research, School of Oncology, Peking University, Beijing, 100034, PR China.
authors.forename: Jin-Ying
authors.initials: JY
authors.lastname: Ning
authors.forename: Cheng-Chao
authors.initials: CC
authors.lastname: Shou
mesh_terms: D000818:Animals; D002471:Cell Transformation, Neoplastic; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D009175:Mycoplasma Infections; D009857:Oncogenes; D010051:Ovarian Neoplasms / Q000235:genetics / Q000382:microbiology*; D013274:Stomach Neoplasms / Q000235:genetics / Q000382:microbiology*; D015854:Up-Regulation