The Fc gamma RIIa polymorphism in patients with acute kidney graft rejection.
The Fc gamma RIIa receptors are the most widely distributed of the three classes of Fc receptors and expresses an allelic polymorphism. This polymorphism may modulate the immune response and may be a factor for some diseases. The aim of the study was to evaluate the association between the Fc gamma RIIa polymorphism and acute kidney graft rejection. The study was carried out in 115 kidney allograft recipients. The frequency of acute kidney graft rejection was similar in relation to Fc gamma RIIa genotypes. We suggest that Fc gamma RIIa polymorphism is not important risk factor for acute kidney graft rejection susceptibility.
Pawlik
A
A
Department of Pharmacokinetics and Thetapeutic Drug Monitoring, Szczecin, Poland.
Florczak
M
M
Bak
L
L
Domański
L
L
Rózański
J
J
Dabrowska-Zamojcin
E
E
Machaliński
B
B
Gawrońska-Szklarz
B
B
D000208:Acute Disease; D015703:Antigens, CD / Q000235:genetics*; D001483:Base Sequence; D004247:DNA / Q000235:genetics; D005260:Female; D006084:Graft Rejection / Q000235:genetics* / Q000276:immunology*; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000276:immunology; D008297:Male; D011110:Polymorphism, Genetic; D017452:Receptors, IgG / Q000235:genetics*; D012307:Risk Factors
D015703:Antigens, CD; C080568:Fc gamma receptor IIA; D017452:Receptors, IgG; D004247:DNA