title: Genetic basis of erythromycin resistance in oral bacteria.
abstract: We determined the prevalence of erythromycin-resistant bacteria in the oral cavity and identified mef and erm(B) as the most common resistance determinants. In addition, we demonstrate the genetic linkage, on various Tn1545-like conjugative transposons, between erythromycin and tetracycline resistance in a number of isolates.
authors.affiliation: Division of Infection and Immunity, Eastman Dental Institute for Oral Health Care Sciences, University College London, 256 Gray's Inn Rd., London WC1X 8LD, United Kingdom.
authors.forename: A
authors.initials: A
authors.lastname: Villedieu
authors.forename: M L
authors.initials: ML
authors.lastname: Diaz-Torres
authors.forename: A P
authors.initials: AP
authors.lastname: Roberts
authors.forename: N
authors.initials: N
authors.lastname: Hunt
authors.forename: R
authors.initials: R
authors.lastname: McNab
authors.forename: D A
authors.initials: DA
authors.lastname: Spratt
authors.forename: M
authors.initials: M
authors.lastname: Wilson
authors.forename: P
authors.initials: P
authors.lastname: Mullany
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development; D015139:Blotting, Southern; D004251:DNA Transposable Elements / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics; D024881:Drug Resistance, Bacterial; D004917:Erythromycin / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009055:Mouth / Q000382:microbiology*; D010957:Plasmids / Q000235:genetics; D011496:Protein Methyltransferases / Q000235:genetics; D013753:Tetracycline Resistance; D014157:Transcription Factors / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D004251:DNA Transposable Elements; D004268:DNA-Binding Proteins; C111931:ELF4 protein, human; C086680:ETV5 protein, human; D014157:Transcription Factors; D004917:Erythromycin; D011496:Protein Methyltransferases