title: Limited Wegener's granulomatosis presenting with complete heart block.
abstract: Complete heart block associated with Wegener's granulomatosis (WG) is rare, and has not previously been reported with 'limited' WG. The case of a 36-year-old man who presented with complete heart block due to 'limited' WG [positive cytoplasmic antineutrophil cytoplasmic antibodies (c-ANCA) on indirect immunofluorescence, positive serum antibodies to proteinase-3, and inflammatory sinus disease seen on computerized tomography (CT) without renal or pulmonary involvement] is presented. In addition, a gallium-scan fused with a myocardial perfusion scan and cardiac magnetic resonance imaging (MRI) suggested focal inflammation near the atrioventricular (AV) node.
authors.affiliation: Division of Rheumatology, Department of Internal Medicine, University of New Mexico Health Sciences Center, Veterans Administration Hospital, Albuquerque, NM 87131, USA. NGhaussy@salud.unm.edu
authors.forename: N O
authors.initials: NO
authors.lastname: Ghaussy
authors.forename: T W
authors.initials: TW
authors.lastname: Du Clos
authors.forename: P A
authors.initials: PA
authors.lastname: Ashley
mesh_terms: D000328:Adult; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis*; D004562:Electrocardiography; D004797:Enzyme-Linked Immunosorbent Assay; D005500:Follow-Up Studies; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis*; D006327:Heart Block / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D035583:Rare Diseases; D018570:Risk Assessment; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic