An efficient and general method for the synthesis of alpha,omega-difunctional reduced polypropionates by Zr-catalyzed asymmetric carboalumination: synthesis of the scyphostatin side chain.
Tan
Ze
Z
Herbert C. Brown Laboratories of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907-2084, USA.
Negishi
Ei-Ichi
E
D000535:Aluminum / Q000737:chemistry*; D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D008968:Molecular Conformation; D011108:Polymers / Q000138:chemical synthesis*; D011422:Propionates / Q000138:chemical synthesis*; D011753:Pyrones / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D015040:Zirconium / Q000737:chemistry*
D000577:Amides; D011108:Polymers; D011422:Propionates; D011753:Pyrones; C121123:scyphostatin; D002244:Carbon; D015040:Zirconium; D000535:Aluminum