Localized peribronchial adenomyomatous hyperplasia arising from an ectatic bronchus with aspergilloma.
A cavitary lesion containing a mobile nodule was found in the right lower lung of a 68-year-old woman. Suspecting bronchiectasis with a fungus ball, we performed wedge resection of the right lower lobe. Light microscopy revealed that a uniformly thickened muscular layer around the ectatic bronchus with aspergilloma had formed a focally protruding mass. It was composed of bundles of hyperplastic smooth muscle and entrapped glandular structures. Given the histological similarity between the lesion and adenomyomatous hyperplasia of the gallbladder, we diagnosed the previously undescribed lesion as "localized peribronchial adenomyomatous hyperplasia". This condition should be recognized as a tumor-like form of smooth muscle hyperplasia induced by bronchiectasis and inflammation.
Mito
Katsuhiko
K
Department of Pathology, Faculty of Medicine, Oita University, Oita, Japan. kmito@med.oita-u.ac.jp
Kashima
Kenji
K
Daa
Tsutomu
T
Miura
Takashi
T
Nakayama
Iwao
I
Yokoyama
Shigeo
S
D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D001228:Aspergillosis / Q000150:complications* / Q000473:pathology; D001980:Bronchi / Q000473:pathology; D001984:Bronchial Neoplasms / Q000473:pathology*; D001987:Bronchiectasis / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D006965:Hyperplasia; D009130:Muscle, Smooth / Q000473:pathology