Restricted expression domains of Ezrin in developing epithelia of the chick.
Ezrin is a member of the ERM- (Ezrin-Radixin-Moesin-) family of actin binding proteins, which function as linkers of the cortical cytoskeleton to components of the plasma membrane. Additional roles for Ezrin in intracellular signalling and ion channel regulation were suggested. We found Ezrin mRNA in the anterior endo- and mesoderm of chick gastrula stage embryos. In these tissues Ezrin message is strongly expressed throughout early development of the foregut (pharynx) and heart tube. During later stages of development, highly restricted expression domains of Ezrin mRNA were detected in the endodermal lining of the pharyngeal pouches, the mesonephric duct and tubuli, and in the ectodermal placodes giving rise to the inner ear, eye lens and olfactory epithelium.
Richter
Ulrike
U
Max-Planck-Institut für Biophysikalische Chemie, Am Fassberg, 37077 Göttingen, Germany.
Wittler
Lars
L
Kessel
Michael
M
D000818:Animals; D002642:Chick Embryo; D003598:Cytoskeletal Proteins; D004475:Ectoderm / Q000378:metabolism; D004707:Endoderm / Q000378:metabolism; D004848:Epithelium / Q000378:metabolism*; D005727:Ganglia, Spinal / Q000378:metabolism; D015870:Gene Expression / Q000502:physiology*; D020869:Gene Expression Profiling; D008648:Mesoderm / Q000378:metabolism; D010750:Phosphoproteins / Q000235:genetics* / Q000378:metabolism*; D000099149:Ezrin
D003598:Cytoskeletal Proteins; D010750:Phosphoproteins; D000099149:Ezrin