title: Second malignant neoplasms following hematopoietic stem cell transplantation.
abstract: Hematopoietic stem cell transplantation is being successfully used to treat a variety of malignant and nonmalignant disorders. This therapy has resulted in an increasing number of survivors who are at risk for adverse long-term outcomes, including the development of second and subsequent malignant neoplasms. We review the incidence and spectrum of posttransplantation malignancies and discuss risk factors and future directions for research.
authors.affiliation: University of Washington, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. debra.friedman@seattlechildrens.org
authors.forename: Debra L
authors.initials: DL
authors.lastname: Friedman
authors.forename: Wendy
authors.initials: W
authors.lastname: Leisenring
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Schwartz
authors.forename: H Joachim
authors.initials: HJ
authors.lastname: Deeg
mesh_terms: D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D015994:Incidence; D016609:Neoplasms, Second Primary / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors; D017741:Survivors