title: Recalcitrant adverse reaction to vitamin K: response to pulsed dye laser.
abstract: BACKGROUND
  Adverse cutaneous reaction to vitamin K manifests in sclerodermatous or erythematous plaque-like reactions. Most of the cases with erythematous plaque-like dermatitis arising at the site of intramuscular vitamin K injection were recalcitrant and did not respond to various attempts with topical and intralesional corticosteroid.
  
  
  OBJECTIVE
  The objective was to describe a 25-year-old woman with recalcitrant adverse reaction owing to vitamin K who was successfully treated with pulsed dye laser.
  
  
  METHODS
  Two consecutive pulsed dye laser treatments were performed 3 weeks apart with 450-microec pulse duration, 585-nm pulse width, and fluence of 5 and 7 J/cm(2), respectively, using a 7-mm handpiece.
  
  
  RESULTS
  One week after the second treatment, her skin lesion was cleared and she was followed without recurrence for 7 months.
  
  
  CONCLUSIONS
  Although the precise mechanism remains yet to be proven, we have demonstrated successful treatment of localized adverse cutaneous reaction to vitamin K in one patient with the pulsed dye laser.
authors.affiliation: Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Jeanne
authors.initials: J
authors.lastname: Jung
authors.forename: Sung Bin
authors.initials: SB
authors.lastname: Cho
authors.forename: Kee Yang
authors.initials: KY
authors.lastname: Chung
mesh_terms: D000328:Adult; D002081:Buttocks; D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D028022:Low-Level Light Therapy; D012008:Recurrence; D014812:Vitamin K / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D014812:Vitamin K