title: Occupational exposure to diesel and gasoline engine exhausts and risk of lung cancer among Finnish workers.
abstract: BACKGROUND
  Studies on engine exhausts and lung cancer have given inconsistent results.
  
  
  METHODS
  Economically active Finns were followed-up for lung cancer during 1971-95 (33,664 cases). Their Census occupations in 1970 were converted to exposures to diesel and gasoline engine exhausts with a job-exposure matrix. The relative risks (RRs) for cumulative exposure (CE) were defined by Poisson regression, adjusted for smoking, asbestos, and quartz dust exposure, and socioeconomic status.
  
  
  RESULTS
  RR for engine exhausts among men did not increase with increasing CE. In women, RR for gasoline engine exhaust was 1.58 (95% CI 1.10-2.26) in the CE-category of 1-99 mg/m(3)-y and 1.66 (1.11-2.50) among those with > or =100 mg/m(3)-y (lag 20 years). With a lag of 10 years RR for the middle/highest diesel exhaust category in women was 1.42 (0.94-2.13).
  
  
  CONCLUSIONS
  Occupational exposure to engine exhausts was not consistently associated with lung cancer in this study, possibly due to low exposure levels.
authors.affiliation: Finnish Institute of Occupational Health, Topeliuksenk, 00250 Helsinki, Finland. johannes.guo@occuphealth.fi
authors.forename: Johannes
authors.initials: J
authors.lastname: Guo
authors.forename: Timo
authors.initials: T
authors.lastname: Kauppinen
authors.forename: Pentti
authors.initials: P
authors.lastname: Kyyrönen
authors.forename: Marja-Liisa
authors.initials: ML
authors.lastname: Lindbohm
authors.forename: Pirjo
authors.initials: P
authors.lastname: Heikkilä
authors.forename: Eero
authors.initials: E
authors.lastname: Pukkala
mesh_terms: D000328:Adult; D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D009790:Occupations; D016012:Poisson Distribution; D012042:Registries / Q000706:statistics & numerical data; D018570:Risk Assessment; D012307:Risk Factors; D001335:Vehicle Emissions / Q000633:toxicity*
chemical_list: D001335:Vehicle Emissions