title: [A study of prostaglandine E(2) level in root canal fluid of patients with periapical lesions]
abstract: It has been reported that there is close relationship between prostaglandine E(PGE) and the pathogenesis of periapical lesions, In this study the root canal fluid(RCF) of 35 cases with acute,chronic and convalescent periradicular lesions were collected with assessed by the method of radioimmunoassay.The results showed:RCF-PGE(2) levels were increased with the severity of periapical lesion(P<0.01).The PGE level was highest in acute periradicular lesions,middle in chronic,and lowest in convalescent.RCF-PGE(2) levels were significantly different between either two groups of the three groups of patients(P<0.01-0.05).This study repeatedly proved that PGE(2) has certain effect in pathogenesis of periapical lesions and it is meaningful in guiding clinical therapy.It was also pointed out that RCF is one of worthwhile samples in the study of periradicular lesion.
authors.affiliation: Department of Oral Medicine,Stomatology Hospital,China Medical University. Liaoning 110002,China.
authors.forename: X F
authors.initials: XF
authors.lastname: Wang
authors.forename: X
authors.initials: X
authors.lastname: Hu
authors.forename: Y
authors.initials: Y
authors.lastname: Ning