title: Novel nonpeptidic inhibitors of HIV-1 protease obtained via a new multicomponent chemistry strategy.
abstract: Using a newly developed multicomponent chemistry strategy in combination with structure based drug design, a new class of HIV-1 protease inhibitors has been obtained.
authors.affiliation: Morphochem AG, Gmunderstr--37-37a, 81379 München, Germany.
authors.forename: Nasser A M
authors.initials: NA
authors.lastname: Yehia
authors.forename: Walfrido
authors.initials: W
authors.lastname: Antuch
authors.forename: Barbara
authors.initials: B
authors.lastname: Beck
authors.forename: Sibylle
authors.initials: S
authors.lastname: Hess
authors.forename: Vesna
authors.initials: V
authors.lastname: Schauer-Vukasinović
authors.forename: Michael
authors.initials: M
authors.lastname: Almstetter
authors.forename: Patrick
authors.initials: P
authors.lastname: Furer
authors.forename: Eberhardt
authors.initials: E
authors.lastname: Herdtweck
authors.forename: Alexander
authors.initials: A
authors.lastname: Dömling
mesh_terms: D001665:Binding Sites / Q000502:physiology; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D016333:HIV Protease / Q000378:metabolism*; D017320:HIV Protease Inhibitors / Q000138:chemical synthesis* / Q000378:metabolism* / Q000494:pharmacology
chemical_list: D017320:HIV Protease Inhibitors; D016333:HIV Protease