title: A novel method for the detection of transient myocardial ischaemia using body surface electrocardiac mapping.
abstract: BACKGROUND
  The limitations of the 12-lead ECG in the detection of myocardial ischaemia are well known. This study sought to test the hypothesis that a Body Surface Mapping (BSM) system can detect and localise the transient regional ischaemia induced by elective percutaneous coronary intervention (PCI) in patients with stable angina.
  
  
  RESULTS
  25 patients undergoing elective single vessel PCI were studied: 11 with RCA lesions, 9 with LAD lesions and 5 with circumflex lesions. Patients had BSM readings every 30 s following the inflation of a dilating balloon in the target vessel for 1 min. BSMs were analysed for ST segment change at 60 ms after the J point (ST60). Peak ST changes were analysed and colour map reconstruction made. Characteristic ST segment changes in each arterial domain were observed following inflation of the balloon. Maximal change occurred in a standard V lead on only 2/46 occasions. Statistically significant rapid rise and fall of ST 60 readings were observed indicating the onset recovery and location of the transient ischaemia. A novel method for the presentation of colour map reconstruction that removes baseline noise has been developed.
  
  
  CONCLUSIONS
  These data confirm the hypothesis that this BSM system can detect and display transient myocardial ischaemia. BSM may represent a novel clinical tool for the assessment of clinical ischaemia.
authors.affiliation: Department of Emergency Medicine, Manchester Royal Infirmary, Oxford Road, M13 9WL, UK.
authors.forename: Simon
authors.initials: S
authors.lastname: Carley
authors.forename: Kevin
authors.initials: K
authors.lastname: Mackway-Jones
authors.forename: Michelle
authors.initials: M
authors.lastname: Jenkins
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Darlington
authors.forename: Farzin
authors.initials: F
authors.lastname: Fath-Ordoubadi
authors.forename: Nicholas
authors.initials: N
authors.lastname: Curzen
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D018780:Body Surface Potential Mapping; D003331:Coronary Vessels / Q000473:pathology / Q000601:surgery; D006801:Humans; D017202:Myocardial Ischemia / Q000175:diagnosis* / Q000628:therapy; D012815:Signal Processing, Computer-Assisted; D016896:Treatment Outcome