title: [Temperature sensitivity of the cholinergic response in cortical neurons of guinea pigs].
abstract: A temperature change from 20 to 36 degrees C results in a significant increase of neuronal responses to iontophoretic application of acetylcholine in parietal cortex slices. The most intensive changes in cholinergic responses occurred in two temperature zones: 27-29 degrees C and 34-36 degrees C. Increase in the responses to acetylcholine accompany with increasing spontaneous spike activity.
authors.affiliation: Institute of Higher Nervous Activity and Neurophysiology, Russian Acad. Sci., Moscow 117485, Russia.
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Mednikova
authors.forename: N V
authors.initials: NV
authors.lastname: Pasikova
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology / Q000502:physiology*; D000200:Action Potentials; D000818:Animals; D002540:Cerebral Cortex / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D006168:Guinea Pigs; D006361:Heating; D066298:In Vitro Techniques; D007478:Iontophoresis; D009474:Neurons / Q000187:drug effects / Q000502:physiology*
chemical_list: D000109:Acetylcholine