The collagen receptor subfamily of the integrins.
The four collagen receptor integrins, alpha1beta1, alpha2beta1, alpha10beta1 and alpha11beta1, form a structurally and functionally distinct subgroup when compared to other members of the integrin family. In this review, we discuss the structures of these receptors and their differences in collagen binding and signalling function.
White
Daniel J
DJ
Cell Biology, Department of Biological and Environmental Science, University of Jyväskylä, P.O. Box 35, FIN-40014 Jyväskylä, Finland. dan@chalkie.org.uk
Puranen
Santeri
S
Johnson
Mark S
MS
Heino
Jyrki
J
D000818:Animals; D006801:Humans; D016023:Integrins / Q000737:chemistry* / Q000378:metabolism / Q000502:physiology; D008024:Ligands; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D038981:Receptors, Collagen / Q000737:chemistry* / Q000378:metabolism / Q000502:physiology; D015398:Signal Transduction
D016023:Integrins; D008024:Ligands; D038981:Receptors, Collagen