title: [Expression of water channel protein 1 in the lung of the drown rat].
abstract: OBJECTIVE
  To determine the expression of water channel 1 protein in the lung of drown rat and that of after death thrown into the water.
  
  
  METHODS
  Immunohistochemical method was used and the computer image analysis was conducted to detect the distribution of AQP1.
  
  
  RESULTS
  The positive expression of AQP1 was seen in the capillary endotheliocyte of the interstitial and around bronchi and in the alveolar endothelial cells. The value of intergrated optical density was statistical significant.
  
  
  CONCLUSIONS
  It suggests that AQP1 is one of sensitive signs to distinguish ante-mortem and postmortem immersion.
authors.affiliation: West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
authors.forename: Hua-zi
authors.initials: HZ
authors.lastname: Hu
authors.forename: Chen
authors.initials: C
authors.lastname: Yang
authors.forename: Liao
authors.initials: L
authors.lastname: Zhi-gang
mesh_terms: D000818:Animals; D051398:Aquaporin 1; D020346:Aquaporins / Q000032:analysis / Q000378:metabolism*; D004332:Drowning / Q000378:metabolism*; D042783:Endothelial Cells / Q000378:metabolism; D007150:Immunohistochemistry; D008168:Lung / Q000378:metabolism*; D008565:Membrane Proteins / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: C496022:Aqp1 protein, rat; D020346:Aquaporins; D008565:Membrane Proteins; D051398:Aquaporin 1