On the mechanics of the actin filament: the linear relationship between stiffness and yield strength allows estimation of the yield strength of thin filament in vivo.
Comparison of the behaviour of actin filaments either modified with tetramethylrhodamine iodoacetamide or decorated with tetramethylrhodamine-phalloidin or with tropomyosin or with myosin subfragment 1 shows that, in all the cases, yield strength is linearly related to stiffness.
Grazi
Enrico
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Dipartimento di Biochimica e Biologia Molecolare, Università di Ferrara, Via Borsari 46, 44100 Ferrara, Italy. gre@dns.unife.it
Cintio
Orietta
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Trombetta
Giorgio
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D008841:Actin Cytoskeleton / Q000737:chemistry* / Q000502:physiology*; D000199:Actins / Q000737:chemistry* / Q000502:physiology*; D016014:Linear Models; D009119:Muscle Contraction / Q000502:physiology*; D015879:Myosin Subfragments / Q000737:chemistry / Q000502:physiology; D010590:Phalloidine / Q000031:analogs & derivatives* / Q000737:chemistry; D012235:Rhodamines / Q000737:chemistry; D013718:Tensile Strength; D014335:Tropomyosin / Q000737:chemistry / Q000502:physiology
D000199:Actins; D015879:Myosin Subfragments; D012235:Rhodamines; D014335:Tropomyosin; D010590:Phalloidine; C034996:tetramethylrhodamine iodoacetamide; C041085:tetramethylrhodaminylphalloidine