Metastatic microcystic adnexal carcinoma: an autopsy case.
BACKGROUND
Microcystic adnexal carcinoma is a clinically aggressive, local destructive sweat gland carcinoma with a high rate of recurrence, but regional or distant metastasis is quite rare.


OBJECTIVE
The objective was to describe an autopsy case of microcystic adnexal carcinoma with hematogenous metastasis and perineural intracranial spreads.


METHODS
This is an autopsy case of a 73-year-old woman with hematogenous metastasis of microcystic adnexal carcinoma followed for more than 20 years.


RESULTS
The autopsy study revealed that the metastatic lesions were located in the perineural intracranial spread, left clavicle bone, bilateral 12th ribs, and liver.


CONCLUSIONS
Physicians should be aware that microcystic adnexal carcinoma is capable of metastasis to the liver and bones with intracranial spread along the optic nerve into the cranium.
Ohta
Masayoshi
M
Department of Plastic and Reconstructive Surgery, Kyoto University Hospital, Kyoto, Japan. emp-ota@kuhp.kyoto-u.ac.jp
Hiramoto
Michiaki
M
Ohtsuka
Hisashi
H
D000236:Adenoma / Q000175:diagnosis* / Q000473:pathology; D000368:Aged; D001344:Autopsy; D001859:Bone Neoplasms / Q000175:diagnosis / Q000556:secondary; D002968:Clavicle; D003937:Diagnosis, Differential; D005145:Face; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000556:secondary; D008279:Magnetic Resonance Imaging; D009362:Neoplasm Metastasis; D012272:Ribs; D013544:Sweat Gland Neoplasms / Q000175:diagnosis* / Q000473:pathology