title: Enzymatic reactions by five chalcone synthase homologs from hop (Humulus lupulus L.).
abstract: The enzyme activities encoded in five cDNAs for chalcone synthase (CHS) homologs from hop were investigated. Only valerophenone synthase (VPS) and CHS_H1 showed both naringenin-chalcone and phlorisovalerophenone forming activity. Narigenin-chalcone production by VPS was much lower than by CHS_H1. Therefore, it is highly possible that flavonoid depends mainly on CHS_H1, while bitter acid biosynthesis depends mainly on VPS and CHS_H1.
authors.affiliation: Bioresources Research and Development Laboratories, Sapporo Breweries, Ltd, Gunma, Japan. yukio.okada@sapporobeer.co.jp
authors.forename: Yukio
authors.initials: Y
authors.lastname: Okada
authors.forename: Yukie
authors.initials: Y
authors.lastname: Sano
authors.forename: Takafumi
authors.initials: T
authors.lastname: Kaneko
authors.forename: Ikuro
authors.initials: I
authors.lastname: Abe
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Noguchi
authors.forename: Kazutoshi
authors.initials: K
authors.lastname: Ito
mesh_terms: D000214:Acyl Coenzyme A / Q000378:metabolism; D000217:Acyltransferases / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D044950:Flavanones / Q000096:biosynthesis; D027582:Humulus / Q000201:enzymology* / Q000235:genetics
chemical_list: D000214:Acyl Coenzyme A; D044950:Flavanones; D000217:Acyltransferases; C020141:flavanone synthetase