Solid organ transplantation and HIV infection.
HIV infection has been traditionally considered to be an absolute contraindication for solid organ transplantation. Recent advances in HIV treatment, as highly active antiretroviral therapy (HAART), significantly reduced HIV-related mortality and morbidity. At the same time the number of HIV-infected patients with end-stage organ diseases constantly increased. Current data describing solid organ transplantation in HIV-infected patients demonstrated comparable outcome to that in the HIV-negative population. In light of this, solid organ transplantation should be considered as a treatment option for selected HIV-positive patients with end-stage organ disease.
Polak
Wojciech G
WG
Department of Vascular, General and Transplant Surgery, Medical University in Wroclaw, Poland. adalbert@mp.pl
Gładysz
Andrzej
A
D017088:AIDS-Related Opportunistic Infections / Q000150:complications; D023241:Antiretroviral Therapy, Highly Active; D000075202:Contraindications; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy / Q000635:transmission; D006801:Humans; D007165:Immunosuppression Therapy; D017758:Infectious Disease Transmission, Patient-to-Professional; D016030:Kidney Transplantation; D016031:Liver Transplantation; D009369:Neoplasms / Q000150:complications; D016377:Organ Transplantation / Q000941:ethics