Isolation and epimerization kinetics of the first diastereoisomer of an inherently chiral uranyl-salophen complex.
The first diastereoisomeric mixture of an inherently chiral uranyl-salophen complex was prepared using (S)-naproxen as a chiral derivatizing agent. Slow crystallization from diisopropyl ether-chloroform afforded one pure diastereoisomer in 45% yield. Kinetic studies allowed the determination of the epimerization rate. [reaction--see text]
Dalla Cort
Antonella
A
Dipartimento di Chimica and IMC-CNR Sezione Meccanismi di Reazione, Università La Sapienza, Box 34 Roma 62, 00185 Rome, Italy.
Mandolini
Luigi
L
Pasquini
Chiara
C
Schiaffino
Luca
L