title: Interrelationship between Autism Diagnostic Observation Schedule-Generic (ADOS-G), Autism Diagnostic Interview-Revised (ADI-R), and the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) classification in children and adolescents with mental retardation.
abstract: The interrelationship between the Autism Diagnostic Interview-Revised (ADI-R), Autism Diagnostic Observation Schedule-Generic (ADOS-G) and clinical classification was studied in 184 children and adolescents with Mental Retardation (MR). The agreement between the ADI-R and ADOS-G was fair, with a substantial difference between younger and older children (5-8 vs. 8+ years). Compared with the Diagnostic and Statistical Manual of Mental Disorders-IV-TR (DSM-IV-TR) classification of Autistic Disorder (AD) and Pervasive Developmental Disorder (PDD), both instruments measure AD or PDD validly and reliably. Even in low-functioning children the interrelationship between the instruments and the clinical classification was satisfactory. The combination of ADI-R and ADOS-G identifies AD or PDD, as described in the DSM-IV-TR, most appropriately. Both instruments seem to be of great value in the diagnostic process of PDD in children and adolescents with MR.
authors.affiliation: Department of Psychiatry, Child and Adolescent Psychiatry, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. a.de.bilt@accare.nl
authors.forename: Annelies
authors.initials: A
authors.lastname: de Bildt
authors.forename: Sjoerd
authors.initials: S
authors.lastname: Sytema
authors.forename: Cees
authors.initials: C
authors.lastname: Ketelaars
authors.forename: Dirk
authors.initials: D
authors.lastname: Kraijer
authors.forename: Erik
authors.initials: E
authors.lastname: Mulder
authors.forename: Fred
authors.initials: F
authors.lastname: Volkmar
authors.forename: Ruud
authors.initials: R
authors.lastname: Minderaa
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001321:Autistic Disorder / Q000175:diagnosis* / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000175:diagnosis* / Q000453:epidemiology; D009426:Netherlands / Q000453:epidemiology; D016017:Odds Ratio; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires; D013997:Time Factors