title: Live delivery rates in subfertile women with Asherman's syndrome after hysteroscopic adhesiolysis using the resectoscope or the Versapoint system.
abstract: The purpose of this study was to report on a 10-year experience in the treatment of subfertile women with intrauterine adhesions using the resectoscope or the Versapoint system. Forty-six subfertile women with stage I (n = 6), stage II (n = 25) and stage III (n = 15) intrauterine adhesions underwent adhesiolysis with the use of the resectoscope (n = 21) or the Versapoint system (n = 26). Synechiolysis was successful in 43 women (93.5%) after the first attempt. In 13 out of 14 women (92.9%) with oligo/amenorrhoea at presentation, restoration of menses was reported after adhesiolysis (Versapoint: 9/9, resectoscope: 4/5). Overall live delivery rates according to stage of intrauterine adhesions were 33.3, 44.4 and 46.7% for stages I, II and III respectively. Similar cumulative delivery rates were achieved in patients with no additional infertility factors who attempted to conceive naturally after adhesiolysis using the Versapoint (71.7%) or the resectoscope (60%). Ten gestations ended in preterm delivery (50%), while in two of the women who delivered, a hysterectomy was performed due to placenta accreta. In conclusion, hysteroscopic adhesiolysis offers a real chance of parenthood in a substantial proportion of infertile couples either by using the Versapoint system or the resectoscope.
authors.affiliation: Centre for Reproductive Medicine, Dutch-Speaking Brussels Free University, Laarbeeklaan 101, 1090 Brussels, Belgium.
authors.forename: Konstantinos A
authors.initials: KA
authors.lastname: Zikopoulos
authors.forename: Efstratios M
authors.initials: EM
authors.lastname: Kolibianakis
authors.forename: Peter
authors.initials: P
authors.lastname: Platteau
authors.forename: Luc
authors.initials: L
authors.lastname: de Munck
authors.forename: Herman
authors.initials: H
authors.lastname: Tournaye
authors.forename: Paul
authors.initials: P
authors.lastname: Devroey
authors.forename: Michel
authors.initials: M
authors.lastname: Camus
mesh_terms: D000328:Adult; D005260:Female; D006175:Gynatresia / Q000601:surgery*; D006801:Humans; D020702:Hysteroscopes; D015907:Hysteroscopy; D007247:Infertility, Female / Q000601:surgery*; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D000267:Tissue Adhesions / Q000601:surgery