title: First human experience with stent-based ventricle-to-coronary artery bypass.
abstract: Stent-based ventricle-to-coronary artery bypass (VSTENT) has been shown experimentally to provide systolic instead of physiological diastolic blood flow directly from the left ventricle to a coronary artery distal to a high-grade stenosis. We report on the first successful surgical implantation of a VSTENT in a patient with coronary artery disease. At 3-month follow-up, the VSTENT was patent and showed sufficient regional blood flow at rest with a significant flow reserve. In addition, the patient was asymptomatic during exercise testing. Though encouraging, these observations have to be confirmed and are the subject of an ongoing multicenter study.
authors.affiliation: Department of Internal Medicine I, Grosshadern University Hospital, Munich, Germany. boekstegers@med.uni-muenchen.de
authors.forename: Peter
authors.initials: P
authors.lastname: Boekstegers
authors.forename: Gerhard
authors.initials: G
authors.lastname: Steinbeck
authors.forename: Frank M
authors.initials: FM
authors.lastname: Bengel
authors.forename: Bruno
authors.initials: B
authors.lastname: Reichart
authors.forename: Calin
authors.initials: C
authors.lastname: Vicol
mesh_terms: D000328:Adult; D015906:Angioplasty, Balloon, Coronary; D019917:Blood Vessel Prosthesis Implantation; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003326:Coronary Circulation / Q000502:physiology; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D008297:Male; D009206:Myocardium / Q000473:pathology; D012039:Regional Blood Flow / Q000502:physiology; D015607:Stents