title: [Pulmonary complications in haploidentical bone marrow transplantation].
abstract: To explore the occurrence patterns of pulmonary complications at different stages in haploidentical bone marrow transplantation, a series of clinical data as the onset time, etiology, management choices and prognosis in 18 patients with pulmonary disorders were summarized. The results showed that in 18 out of 70 patients after bone marrow transplantation occurred pulmonary complications which included pneumonia affected by bacteria (7 cases), fungus (5 cases) and cytomegalovirus (CMV, 4 cases), bronchiolitis obliterans organizing pneumonia (BOOP, 1 case), and idiopathic pneumonia syndrome (1 case), out of which 8 cases died. Fungal and CMV pneumonia occurred predominantly 2 to 3 months after transplantation, whereas bacterial pneumonia was observed in the duration of 3 to 12 months and 4 cases of them suffered from secondary fungal infections during treatment. BOOP and idiopathic pneumonia syndrome were diagnosed 12 months and 50 days after transplantation respectively.
  
  
  CONCLUSIONS
  pulmonary complications were commonly seen in haploidentcal bone marrow transplantation, and fungal pneumonia might be the main cause that needs intensive management.
authors.affiliation: Department of Hematology, General Hospital of Air Force, PLA, Beijing 100036, China.
authors.forename: Heng-Xiang
authors.initials: HX
authors.lastname: Wang
authors.forename: Shu-Quan
authors.initials: SQ
authors.lastname: Ji
authors.forename: Ling
authors.initials: L
authors.lastname: Zhu
authors.forename: Mei
authors.initials: M
authors.lastname: Xue
authors.forename: Hui-Ren
authors.initials: HR
authors.lastname: Chen
authors.forename: Hong-Min
authors.initials: HM
authors.lastname: Yan
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
authors.forename: Lian-Ning
authors.initials: LN
authors.lastname: Duan
mesh_terms: D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D018549:Cryptogenic Organizing Pneumonia / Q000209:etiology; D003586:Cytomegalovirus Infections / Q000209:etiology; D005260:Female; D006239:Haplotypes; D006801:Humans; D008171:Lung Diseases / Q000209:etiology*; D008297:Male