Impact of proteomics on bladder cancer research.
Detecting bladder cancer at an early stage and predicting how a tumor will behave and act in response to therapy, as well as the identification of new targets for therapeutic intervention, are among the main areas of research that will benefit from the current explosion in the number of powerful technologies emerging within proteomics. The purpose of this article is to briefly review what has been achieved to date using proteomic technologies and to bring forward novel strategies - based on the analysis of clinically relevant samples - that promise to accelerate the translation of basic discoveries into the daily clinical practice.
Celis
Julio E
JE
Institute of Cancer Biology, Danish Cancer Society, Strandboulevarden 49, DK 2100, Copenhagen, Denmark. jec@cancer.dk
Gromova
Irina
I
Moreira
Jose M A
JM
Cabezon
Teresa
T
Gromov
Pavel
P
D000818:Animals; D016503:Drug Delivery Systems / Q000379:methods / Q000639:trends; D006801:Humans; D040901:Proteomics / Q000379:methods* / Q000639:trends; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000235:genetics*