[Effect of arthropod extracts on the multiplication of Toxoplasma gondii in mouse peritoneal macrophages].
Treatment of toxoplasmosis usually causes secondary effects. It is important to find active substances extracted from natural organisms. In this work we studied some arthropod extracts that have effect against Toxoplasma multiplication inside mouse macrophages. After studying 382 extracts, 23 were selected on the basis of the activity and we found that 13 extracts from orders Polydesmida, Lepidoptera, Orthoptera and Hymenoptera exerted an important inhibition of Toxoplasma multiplication.
Chinchilla Carmona
Misael
M
Centro de Investigación en Enfermedades Tropicales, Departamento de Parasitología, Facultad de Microbiología, Universidad de Costa Rica, 2060, Costa Rica.
Herrera Corrales
Marlen
M
Guerrero Bermúdez
Olga Marta
OM
Jiménez Somarribas
Alberto
A
Tamayo
Guiselle
G
Sittenfeld Appel
Ana
A
Nielsen
Vanessa
V
Hurtado
Priscila
P
D000818:Animals; D001181:Arthropods / Q000737:chemistry* / Q000145:classification; D017737:Macrophages, Peritoneal / Q000469:parasitology*; D051379:Mice; D013997:Time Factors; D014020:Tissue Extracts / Q000494:pharmacology*; D014122:Toxoplasma / Q000187:drug effects*
D014020:Tissue Extracts