title: Molecular evolution of the ATPase subunit of three archaeal sugar ABC transporters.
abstract: The sequence of genes encoding extracellular amylopullulanase and putative maltodextrin ATP binding cassette (ABC) transporter of a hyperthermophilic archaeon, Thermococcus litoralis, was determined. The mdxK gene, which encodes an ATPase subunit of the putative maltodextrin ABC transporter, has extraordinarily high similarity with the malK gene, which encodes an ATPase subunit of trehalose/maltose ABC transporter of the same organism. DNA sequence comparison revealed that the malK gene was generated through the duplication of the mdxK gene before lateral gene transfer of the mal gene cluster from T. litoralis to Pyrococcus furiosus.
authors.affiliation: Department of Biotechnology, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan. himamura-ra@res.titech.ac.jp
authors.forename: Hiromi
authors.initials: H
authors.lastname: Imamura
authors.forename: Beon-Sam
authors.initials: BS
authors.lastname: Jeon
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Wakagi
mesh_terms: D018528:ATP-Binding Cassette Transporters / Q000737:chemistry* / Q000378:metabolism; D000251:Adenosine Triphosphatases / Q000737:chemistry*; D000255:Adenosine Triphosphate / Q000737:chemistry; D001105:Archaea / Q000378:metabolism; D019843:Archaeal Proteins; D001426:Bacterial Proteins / Q000737:chemistry; D001692:Biological Transport; D015139:Blotting, Southern; D004247:DNA / Q000737:chemistry; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli / Q000378:metabolism; D019143:Evolution, Molecular; D018014:Gene Transfer Techniques; D006026:Glycoside Hydrolases / Q000737:chemistry; D008957:Models, Genetic; D008969:Molecular Sequence Data; D005810:Multigene Family; D016366:Open Reading Frames; D010957:Plasmids / Q000378:metabolism; D011134:Polysaccharides / Q000737:chemistry; D019712:Thermococcus / Q000378:metabolism; D013997:Time Factors; D014199:Trehalose / Q000737:chemistry
chemical_list: D018528:ATP-Binding Cassette Transporters; D019843:Archaeal Proteins; D001426:Bacterial Proteins; C432666:MalK protein, Thermococcus litoralis; D011134:Polysaccharides; C008315:maltodextrin; D000255:Adenosine Triphosphate; D004247:DNA; D014199:Trehalose; D006026:Glycoside Hydrolases; C082507:amylopullulanase; D000251:Adenosine Triphosphatases