title: [Research progress on Alzheimer's disease: pathogenesis and medical therapy].
abstract: Alzheimer's disease (AD) is a common disease in elder people. Its incidence rate is about 5% in people above 60 years old. It has become an important factor that seriously impacts the development of families and society, and caused wildly attention all over the world. In this article, we discuss the mechanisms of AD in four aspects and put forward the strategies of drug therapy.
authors.affiliation: Beijing Key Lab for Brain Aging, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, China. xwnriio@public.bta.net.cn
authors.forename: Shu-li
authors.initials: SL
authors.lastname: Sheng
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000188:drug therapy* / Q000209:etiology*; D016229:Amyloid beta-Peptides / Q000378:metabolism*; D016564:Amyloid beta-Protein Precursor / Q000378:metabolism; D017209:Apoptosis / Q000187:drug effects; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D020932:Nerve Growth Factor / Q000378:metabolism; D009454:Neurofibrils / Q000473:pathology; D018697:Nootropic Agents / Q000627:therapeutic use; D058225:Plaque, Amyloid / Q000378:metabolism; D013569:Synapses / Q000473:pathology
chemical_list: D016229:Amyloid beta-Peptides; D016564:Amyloid beta-Protein Precursor; D002800:Cholinesterase Inhibitors; D018697:Nootropic Agents; D020932:Nerve Growth Factor