Yeast activator proteins and stress response: an overview.
Yeast, and especially Saccharomyces cerevisiae, are continuously exposed to rapid and drastic changes in their external milieu. Therefore, cells must maintain their homeostasis, which is achieved through a highly coordinated gene expression involving a plethora of transcription factors, each of them performing specific functions. Here, we discuss recent advances in our understanding of the function of the yeast activator protein family of eight basic-leucine zipper trans-activators that have been implicated in various forms of stress response.
Rodrigues-Pousada
Claudina Amélia
CA
Stress and Genomics Laboratory, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Avenida da República, Apt. 127, 2781-901 Oeiras Codex, Portugal. claudina@itqb.unl.pt
Nevitt
Tracy
T
Menezes
Regina
R
Azevedo
Dulce
D
Pereira
Jorge
J
Amaral
Catarina
C
D000595:Amino Acid Sequence; D005656:Fungal Proteins / Q000737:chemistry / Q000502:physiology*; D015966:Gene Expression Regulation, Fungal; D008954:Models, Biological; D008969:Molecular Sequence Data; D005810:Multigene Family; D009997:Osmotic Pressure; D018384:Oxidative Stress; D012441:Saccharomyces cerevisiae / Q000378:metabolism / Q000502:physiology; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D014157:Transcription Factors / Q000378:metabolism
C082904:CAD1 protein, S cerevisiae; D005656:Fungal Proteins; D029701:Saccharomyces cerevisiae Proteins; D014157:Transcription Factors; C086677:YAP1 protein, S cerevisiae