title: Intranasal schwannoma in a young woman.
abstract: A rare case of a schwannoma arising from the middle meatus in a 24-year-old woman is reported. The patient presented with a 12-month history of right-sided nasal obstruction, rhinorrhoea, anosmia, headache and recurrent minor nosebleeds. Examination of the right nasal cavity revealed a polypoidal mass. Computerised tomography showed the mass completely occluding the nasal passage with evidence of a secondary maxillary sinusitis. She underwent a complete intranasal excision of the polypoidal mass which was arising from the right middle meatus. The histological features of the lesion were consistent with a schwannoma including diffuse immunoreactivity for S-100 protein. This case illustrates the need to consider schwannoma, amongst many other lesions, in the differential diagnosis of a unilateral nasal mass and reinforces the established principle of sending all material removed from the nose for histological examination.
authors.affiliation: Department of Ear, Nose and Throat Surgery, Guy's and St Thomas' Hospital, London, UK. randm.persaud@ukgateway.net
authors.forename: R A P
authors.initials: RA
authors.lastname: Persaud
authors.forename: D
authors.initials: D
authors.lastname: Hajioff
authors.forename: E B
authors.initials: EB
authors.lastname: Chevretton
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D015508:Nasal Obstruction / Q000209:etiology; D009442:Neurilemmoma / Q000175:diagnosis* / Q000601:surgery; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed