Biomedicine. Parkinson's--divergent causes, convergent mechanisms.
Greenamyre
J Timothy
JT
Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA. jgreena@emory.edu
Hastings
Teresa G
TG
D000818:Animals; D001921:Brain / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism; D042967:Electron Transport Complex I / Q000378:metabolism; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D008928:Mitochondria / Q000201:enzymology / Q000378:metabolism*; D009154:Mutation; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000378:metabolism; D009474:Neurons / Q000378:metabolism; D015513:Oncogene Proteins / Q000235:genetics / Q000378:metabolism; D018384:Oxidative Stress; D010300:Parkinson Disease / Q000209:etiology* / Q000235:genetics* / Q000378:metabolism; D010766:Phosphorylation; D000071617:Protein Deglycase DJ-1; D011494:Protein Kinases / Q000235:genetics* / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism; D051843:Synucleins; D043222:Ubiquitin Thiolesterase / Q000235:genetics / Q000378:metabolism; D044767:Ubiquitin-Protein Ligases / Q000235:genetics / Q000378:metabolism; D000099202:PTEN-Induced Putative Kinase
D004298:Dopamine; D042967:Electron Transport Complex I; D047908:Intracellular Signaling Peptides and Proteins; D009419:Nerve Tissue Proteins; D015513:Oncogene Proteins; D000071617:Protein Deglycase DJ-1; D011494:Protein Kinases; D017382:Reactive Oxygen Species; D051843:Synucleins; D043222:Ubiquitin Thiolesterase; D044767:Ubiquitin-Protein Ligases; D000099202:PTEN-Induced Putative Kinase; C111567:parkin protein; C105131:PARK7 protein, human