title: Prostate cancer and body size at different ages: an Italian multicentre case-control study.
abstract: We investigated the influence of anthropometric measures at diagnosis and at different ages on prostate cancer risk using an Italian multicentre case-control study conducted between 1991 and 2002 of 1294 histologically confirmed cases and 1451 controls admitted to the same network of hospitals for acute non-neoplastic conditions. Height, weight, body mass index (BMI), waist-to-hip ratio, lean body mass 1 year before diagnosis/interview were not significantly associated with risk. However, a positive association with high BMI at age 30 years was found (odds ratio=1.2 for BMI> or =24.7 vs <22.7) and: for less differentiated prostate cancer, with BMI 1 year before diagnosis/interview. This study supports possible relationships between high body mass in young adulthood, and a tendency to high weight throughout adult life, and the risk of prostate cancer.
authors.affiliation: Servizio di Epidemiologia e Biostatistica, Centro di Riferimento Oncologico, Via Pedemontana Occ.le 12, 33081 Aviano (PN), Italy. epidemiology@cro.it
authors.forename: L
authors.initials: L
authors.lastname: Dal Maso
authors.forename: A
authors.initials: A
authors.lastname: Zucchetto
authors.forename: C
authors.initials: C
authors.lastname: La Vecchia
authors.forename: M
authors.initials: M
authors.lastname: Montella
authors.forename: E
authors.initials: E
authors.lastname: Conti
authors.forename: V
authors.initials: V
authors.lastname: Canzonieri
authors.forename: R
authors.initials: R
authors.lastname: Talamini
authors.forename: A
authors.initials: A
authors.lastname: Tavani
authors.forename: E
authors.initials: E
authors.lastname: Negri
authors.forename: A
authors.initials: A
authors.lastname: Garbeglio
authors.forename: S
authors.initials: S
authors.lastname: Franceschi
mesh_terms: D000367:Age Factors; D000368:Aged; D015992:Body Mass Index; D016022:Case-Control Studies; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000209:etiology* / Q000473:pathology; D012307:Risk Factors