New quassinoids, javanicolides C and D and javanicosides B--F, from seeds of Brucea javanica.
Two new quassinoids, javanicolides C and D, and five new quassinoid glucosides, javanicosides B-F, were isolated from the seeds of Brucea javanica, along with eight known quassinoids, i.e., yadanziolides A, C, D, and S, bruceins D and E, brusatol, and the aglycone of yadanzioside D, and 19 known quassinoid glucosides, i.e., yadanziosides A-G, I, and K-P, bruceosides A-C and E, and bruceantinoside A. Their structures were elucidated by analysis of spectroscopic data and chemical evidence.
Kim
Ik Hwi
IH
School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
Takashima
Satoru
S
Hitotsuyanagi
Yukio
Y
Hasuda
Tomoyo
T
Takeya
Koichi
K
D032269:Brucea / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D006868:Hydrolysis; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D036702:Quassins / Q000737:chemistry / Q000302:isolation & purification*; D012639:Seeds / Q000737:chemistry
D004365:Drugs, Chinese Herbal; D005960:Glucosides; D036702:Quassins; C487241:javanicolide C; C487242:javanicolide D