title: Fatal cytophagic histiocytic panniculitis.
abstract: Individual cases of so-called Weber-Christian disease with a bleeding diathesis have been reported for several years. These were originally diagnosed as Weber-Christian disease, but have been recategorized on review as a chronic, visceral, and cutaneous histiocytic (cytophagic) panniculitis, progressing to liver dysfunction and jaundice and a terminal hemorrhagic diathesis. We report here a rare catastrophic form of systemic panniculitis in an adolescent girl. Despite compelling clinical evidence, the diagnosis was made only on postmortem biopsies.
authors.affiliation: Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
authors.forename: Gülten
authors.initials: G
authors.lastname: Seçmeer
authors.forename: Hale
authors.initials: H
authors.lastname: Sakalli
authors.forename: Faysal
authors.initials: F
authors.lastname: Gök
authors.forename: Seza
authors.initials: S
authors.lastname: Ozen
authors.forename: Ates
authors.initials: A
authors.lastname: Kara
authors.forename: Ali Bülent
authors.initials: AB
authors.lastname: Cengiz
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ceyhan
authors.forename: Aytemiz
authors.initials: A
authors.lastname: Gürgey
authors.forename: Safiye
authors.initials: S
authors.lastname: Gögüs
authors.forename: Güler
authors.initials: G
authors.lastname: Kanra
mesh_terms: D000293:Adolescent; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D010201:Panniculitis, Nodular Nonsuppurative / Q000473:pathology*