title: Disappearance of specific immune response after successful therapy of chronic Lyme borreliosis.
abstract: 512 consecutive patients suffering from chronic Lyme borreliosis have been treated according to a standardized therapy regimen which was developed using the results of a controlled trial (Hassler et al., 1990; Hassler, 1992). Follow up was performed for at least 6 (maximum 16) years. In the first two years after initial therapy clinical and serological data were collected every six months including Western blot testing, later once a year.
authors.affiliation: Section of Infectiology, Institute for Hygiene, University of Heidelberg, Germany. Dieter.Hassler@t-online.de
authors.forename: Dieter
authors.initials: D
authors.lastname: Hassler
authors.forename: Matthias
authors.initials: M
authors.lastname: Schnauffer
authors.forename: Hans
authors.initials: H
authors.lastname: Ehrfeld
authors.forename: Elke
authors.initials: E
authors.lastname: Müller
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000907:Antibodies, Bacterial / Q000097:blood; D015153:Blotting, Western; D025065:Borrelia burgdorferi / Q000276:immunology*; D002439:Cefotaxime / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008193:Lyme Disease / Q000188:drug therapy / Q000276:immunology*
chemical_list: D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D002439:Cefotaxime