title: Fetal ultrasonography to prevent irreversible neurological sequelae of neonatal neuroblastoma.
abstract: An intra-abdominal mass was observed by fetal ultrasonography at 32 weeks of gestation. The baby was diagnosed as having neuroblastoma at the time of delivery at 39 weeks and its lower extremities were completely paralyzed. The chemotherapy after birth was quite effective to reduce the mass volume but neurological sequelae failed to improve. By carefully monitoring the movement of extremities, it may have been possible to prevent irreversible by inducing delivery before that state was reached.
authors.affiliation: Department of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima City 890-8520, Japan.
authors.forename: Hironobu
authors.initials: H
authors.lastname: Nagasako
authors.forename: Osamu
authors.initials: O
authors.lastname: Ijichi
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Shinkoda
authors.forename: Naoaki
authors.initials: N
authors.lastname: Ikarimoto
authors.forename: Tatsuri
authors.initials: T
authors.lastname: Kaji
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Nakame
authors.forename: Hideo
authors.initials: H
authors.lastname: Takamatsu
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Kawano
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging; D006801:Humans; D007231:Infant, Newborn; D035002:Lower Extremity / Q000503:physiopathology; D009422:Nervous System Diseases; D009447:Neuroblastoma / Q000150:complications* / Q000000981:diagnostic imaging* / Q000188:drug therapy; D010243:Paralysis / Q000196:embryology / Q000209:etiology* / Q000517:prevention & control; D011247:Pregnancy; D013117:Spinal Cord Compression / Q000196:embryology / Q000209:etiology / Q000517:prevention & control; D016216:Ultrasonography, Prenatal
chemical_list: D000970:Antineoplastic Agents