title: Oligomeric catechins: an enabling synthetic strategy by orthogonal activation and C(8) protection.
abstract: Controlled formation of oligomeric catechins has become possible by an orthogonal synthetic strategy. Bromo-capping of the C(8) position of the flavan skeleton enabled the equimolar coupling of electrophilic and nucleophilic catechin derivatives, enabling an efficient synthetic strategy to complex catechin oligomers.
authors.affiliation: Department of Chemistry, Tokyo Institute of Technology, and Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, O-okayama, Meguro-ku, Tokyo 152-8551, Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Ohmori
authors.forename: Naoko
authors.initials: N
authors.lastname: Ushimaru
authors.forename: Keisuke
authors.initials: K
authors.lastname: Suzuki
mesh_terms: D002392:Catechin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D002625:Chemistry, Organic / Q000379:methods; D019281:Dimerization; D015394:Molecular Structure
chemical_list: D002392:Catechin