Congenital factor VII deficiency.
A 1(1/2)-month-old baby with seizures, lethargy and refusal of feeds was diagnosed to have intracranial hemorrhage due to factor VII deficiency. MRI also demonstrated the unusual presence of a hemorrhagic infarct. The case underscores the importance of carrying out neuroimaging and appropriate hematological studies even in the absence of obvious external bleeding. Hypothesis for increased propensity for intra-cranial hemorrhage is discussed.
Sanghvi
Jagruti P
JP
Department of Pediatrics, Seth G S Medical College and K.E.M Hospital, Parel, Mumbai, India.
Muranjan
Mamta N
MN
Bavdekar
S B
SB
Parmar
Ramesh C
RC
D016913:Blood Component Transfusion / Q000379:methods; D002543:Cerebral Hemorrhage / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D005168:Factor VII Deficiency / Q000150:complications* / Q000235:genetics*; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D018810:Magnetic Resonance Angiography / Q000379:methods; D008297:Male; D018570:Risk Assessment; D016896:Treatment Outcome