title: Stopping warfarin therapy is unnecessary for hand surgery.
abstract: Interruption of appropriate therapeutic warfarin therapy imposes a risk of morbidity and mortality on the patient. Strategies to reduce the risks of interruption impose relatively large costs in terms of prolonged hospital stay, medication and coagulation monitoring. We report a series of 47 consecutive surgical episodes on the hands of 39 patients without interruption of therapeutic warfarin anticoagulation and with an INR of between 1.3 and 2.9. There was no difficulty with intraoperative haemostasis. Two patients had minor bleeding-related complications with no long-term sequelae. The authors conclude that interruption to warfarin therapy is unnecessary if the INR is less than 3.0 and therefore inappropriate for therapeutically anticoagulated patients undergoing hand surgery.
authors.affiliation: Department of Plastic Surgery, The Queen Victoria Hospital, East Grinstead, West Sussex, UK.
authors.forename: D L
authors.initials: DL
authors.lastname: Wallace
authors.forename: M D
authors.initials: MD
authors.lastname: Latimer
authors.forename: H J C R
authors.initials: HJ
authors.lastname: Belcher
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000008:administration & dosage*; D001281:Atrial Fibrillation / Q000188:drug therapy; D005260:Female; D006225:Hand / Q000601:surgery*; D006350:Heart Valve Prosthesis; D006406:Hematoma / Q000209:etiology / Q000628:therapy; D006487:Hemostasis; D006801:Humans; D019934:International Normalized Ratio; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D020521:Stroke / Q000517:prevention & control; D013923:Thromboembolism / Q000517:prevention & control; D014111:Tourniquets; D016896:Treatment Outcome; D014859:Warfarin / Q000008:administration & dosage*
chemical_list: D000925:Anticoagulants; D014859:Warfarin