Antibacterial activity of coriander volatile compounds against Salmonella choleraesuis.
Aliphatic (2E)-alkenals and alkanals characterized from the fresh leaves of the coriander Coriandrum sativum L. (Umbelliferae) were found to possess bactericidal activity against Salmonella choleraesuis ssp. choleraesuis ATCC 35640. (2E)-Dodecenal (C(12)) was the most effective against this food-borne bacterium with the minimum bactericidal concentration (MBC) of 6.25 microg/mL (34 microM), followed by (2E)-undecenal (C(11)) with an MBC of 12.5 microg/mL (74 microM). The time-kill curve study showed that these alpha,beta-unsaturated aldehydes are bactericidal against S. choleraesuis at any growth stage and that their bactericidal action comes in part from the ability to act as nonionic surfactants.
Kubo
Isao
I
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720-3112, USA. ikubo@uclink.berkeley.edu
Fujita
Ken-Ichi
K
Kubo
Aya
A
Nihei
Ken-Ichi
K
Ogura
Tetsuya
T
D000447:Aldehydes / Q000494:pharmacology*; D000473:Alkanes / Q000494:pharmacology*; D000475:Alkenes / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics*; D028526:Coriandrum / Q000737:chemistry*; D012475:Salmonella / Q000187:drug effects*; D014835:Volatilization
D000447:Aldehydes; D000473:Alkanes; D000475:Alkenes; D000900:Anti-Bacterial Agents