Individual thyroid dose estimation for a case-control study of Chernobyl-related thyroid cancer among children of Belarus-part I: 131I, short-lived radioiodines (132I, 133I, 135I), and short-lived radiotelluriums (131MTe and 132Te).
Large amounts of radioiodines were released into the atmosphere during the accident at the Chernobyl nuclear power plant on 26 April 1986. In order to investigate whether the thyroid cancers observed among children in Belarus could have been caused by radiation exposures from the Chernobyl accident, a team of Belarusian, Russian, and American scientists conducted a case-control study to compare cases and controls according to estimated thyroid dose. The primary purpose of this paper is to present detailed information on the estimated thyroid doses, due to intakes of 131I, that were used in the case-control study. The range of the 131I thyroid doses among the 107 cases and the 214 controls was found to extend from 0.00002 to 4.3 Gy, with medians of approximately 0.2 Gy for the cases and 0.07 Gy for the controls. In addition, the thyroid doses resulting from the intakes of short-lived radioiodines (132I, 133I, and 135I) and radiotelluriums (131mTe and 132Te) were estimated and compared to the doses from 131I. The ratios of the estimated thyroid doses from the short-lived radionuclides and from I for the cases and the controls range from 0.003 to 0.1, with median values of approximately 0.02 for both cases and controls.
Gavrilin
Yuri
Y
State Research Center-Institute of Biophysics, Moscow, Russian Federation.
Khrouch
Valeri
V
Shinkarev
Sergey
S
Drozdovitch
Vladimir
V
Minenko
Victor
V
Shemiakina
Elena
E
Ulanovsky
Alexander
A
Bouville
André
A
Anspaugh
Lynn
L
Voillequé
Paul
P
Luckyanov
Nickolas
N
D001822:Body Burden; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure / Q000032:analysis; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007457:Iodine Radioisotopes / Q000032:analysis* / Q000493:pharmacokinetics; D008297:Male; D008954:Models, Biological; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology* / Q000378:metabolism; D009928:Organ Specificity; D011210:Power Plants; D011829:Radiation Dosage; D018788:Radioactive Hazard Release; D011868:Radioisotopes / Q000032:analysis / Q000493:pharmacokinetics; D011874:Radiometry / Q000379:methods; D002094:Republic of Belarus / Q000453:epidemiology; D018570:Risk Assessment / Q000379:methods*; D013691:Tellurium / Q000032:analysis* / Q000493:pharmacokinetics; D013961:Thyroid Gland / Q000737:chemistry*; D013964:Thyroid Neoplasms / Q000453:epidemiology* / Q000378:metabolism; D014455:Ukraine
D007457:Iodine Radioisotopes; D011868:Radioisotopes; D013691:Tellurium