Antiproliferative activity of Thai medicinal plant extracts on human breast adenocarcinoma cell line.
Ethanolic extracts of selected nine Thai medicinal plants were tested for antiproliferative activity against SKBR3 human breast adenocarcinoma cell line using MTT assay. Garcinia mangostana showed the most potent activity. However, all plant extracts showed activity in potential range for further investigation on cancer cells.
Moongkarndi
Primchanien
P
Department of Microbiology, Faculty of Pharmacy, Mahidol University, Rajdhevee, Sri Ayudthaya Rd, Bangkok 10400, Thailand. pypmk@mahidol.ac.th
Kosem
Nuttavut
N
Luanratana
Omboon
O
Jongsomboonkusol
Suna
S
Pongpan
Narongchai
N
D000230:Adenocarcinoma / Q000188:drug therapy / Q000473:pathology; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology; D002455:Cell Division / Q000187:drug effects*; D045744:Cell Line, Tumor / Q000187:drug effects; D005260:Female; D005638:Fruit; D029762:Garcinia mangostana; D006801:Humans; D008516:Medicine, Chinese Traditional; D008517:Phytotherapy; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D013785:Thailand
D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts