Risk of malignant lymphoma associated with human herpesvirus-8: a case-control study in Spain.
No overall increased risk of lymphoma associated with antibodies to human herpesvirus-8 was found in 526 lymphomas and 599 controls (odds ratio (OR)=1.04, 95% confidence interval (CI)=0.62-1.75); significant increases were noted for 19 lymphoplasmacytic lymphomas (OR=4.47, 95% CI=1.34-14.85) and nine low-grade lymphoma/lymphoma B-cell NOS (OR=5.82, 95% CI=1.07-31.73).
de Sanjosé
S
S
Servei d'Epidemiologia i Registre del Cancer, Institut Catala d'Oncologia, L'Hospitalet de Llobregat, Avda. Gran Via s/n km. 2.7, Barcelona 08907, Spain. s.sanjose@ico.scs.es
Goedert
J J
JJ
Marshall
V
V
Bellas
C
C
Benavente
Y
Y
Bosch
R
R
Domingo
A
A
Fernandez de Sevilla
A
A
Servitje
O
O
Whitby
D
D
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006566:Herpesviridae Infections / Q000150:complications*; D019288:Herpesvirus 8, Human / Q000472:pathogenicity*; D006801:Humans; D015994:Incidence; D016393:Lymphoma, B-Cell / Q000821:virology*; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D016133:Polymerase Chain Reaction; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000821:virology*; D013030:Spain
D004279:DNA, Viral