title: [Adrenomedullin in cardiovascular pathology].
abstract: Adrenomedullin (AM), inducing a potent and powerful hypotensive activity caused by dilatation of resistance vessels, has elicited interest for its cardiovascular actions. AM is secreted from various cell type, including vascular endothelial and smooth muscle cell. AM plasma levels are increased in various cardiovascular diseases as heart failure and hypertension and may be involved in pathophysiological changes in cardiovascular diseases.
authors.affiliation: V Clinica Medica, Dipartimento di Fisiopatologia Medica, Policlinico Umberto I, Università La Sapienza, Roma.
authors.forename: Emanuela
authors.initials: E
authors.lastname: Piroli
authors.forename: Claudia
authors.initials: C
authors.lastname: Annoscia
authors.forename: Francesco
authors.initials: F
authors.lastname: Ranieri
authors.forename: Francesca
authors.initials: F
authors.lastname: Priori
authors.forename: Fabio
authors.initials: F
authors.lastname: Rossi
authors.forename: Vittorio
authors.initials: V
authors.lastname: Santiemma
mesh_terms: D053607:Adrenomedullin; D000818:Animals; D002318:Cardiovascular Diseases / Q000097:blood* / Q000503:physiopathology; D002908:Chronic Disease; D005921:Glomerulonephritis / Q000097:blood / Q000503:physiopathology; D006333:Heart Failure / Q000097:blood / Q000503:physiopathology; D006706:Homeostasis; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000503:physiopathology; D006976:Hypertension, Pulmonary / Q000097:blood / Q000503:physiopathology; D009203:Myocardial Infarction / Q000097:blood / Q000503:physiopathology; D010455:Peptides / Q000008:administration & dosage / Q000097:blood / Q000235:genetics / Q000494:pharmacology / Q000502:physiology; D051381:Rats; D012772:Shock, Septic / Q000097:blood / Q000503:physiopathology
chemical_list: D010455:Peptides; D053607:Adrenomedullin