Sentinel lymphadenectomy for circumscribed cutaneous T-cell lymphoma.
BACKGROUND
Sentinel lymphadenectomy has been associated with fewer complications in evaluating regional lymph nodes from melanoma or squamous cell carcinoma. It may also be employed in other malignancies such as localized cutaneous lymphoma. This is the first report demonstrating sentinel lymphadenectomy may be useful on primary cutaneous anaplastic large-cell lymphoma.


OBJECTIVE
The objective was to assess the efficacy of sentinel lymphadenectomy on primary cutaneous anaplastic large-cell lymphoma.


METHODS
Sentinel lymphadenectomy was performed on a patient with a localized CD30+ primary cutaneous anaplastic large-cell lymphoma. After preoperative lymphoscintigraphy, sentinel lymph node was identified by the gamma probe, excised totally, and sent for histopathologic examination.


RESULTS
Sentinel lymphadenectomy was negative for tumor metastasis to sentinel lymph node. Total excision was performed without systemic chemotherapy or immunotherapy. This patient remained tumor-free 36 months after operation.


CONCLUSIONS
Sentinel lymphadenectomy on patients with circumscribed restricted primary cutaneous lymphoma may be beneficial for staging and prognostication of the disease.
Wang
Chun-Hua
CH
Department of Dermatology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Nien
Hsiao-Ching
HC
Hou
Ming-Feng
MF
Chen
Gwo-Shing
GS
Cheng
Shih-Tsung
ST
D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007866:Leg; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D021701:Sentinel Lymph Node Biopsy / Q000379:methods; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology