title: Amyloid tumor in the anterior mediastinum: report of a case.
abstract: A 33-year-old woman being treated for rheumatoid arthritis was referred to our hospital for investigation of a mediastinal mass. A chest computed tomography scan showed an anterior mediastinal mass, 8.5 x 7.0 cm in size, with a cystic lesion and calcification. These findings were suggestive of either a noninvasive thymoma or a mature teratoma. Therefore, we performed tumor resection and thymectomy. Histologically, the tumor consisted of diffuse deposits of massive eosinophilic amorphous material. The tumor was stained red-orange by Congo red, and the staining disappeared following potassium permanganate digestion. Based on these findings, a diagnosis of reactive amyloidosis of the amyloid A-protein-derived type was made. Amyloidosis in the mediastinum has rarely been described.
authors.affiliation: Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan.
authors.forename: Shinzo
authors.initials: S
authors.lastname: Takamori
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Yano
authors.forename: Akihiro
authors.initials: A
authors.lastname: Hayashi
authors.forename: Mari
authors.initials: M
authors.lastname: Fukunaga
authors.forename: Keisuke
authors.initials: K
authors.lastname: Miwa
authors.forename: Kanetaka
authors.initials: K
authors.lastname: Maeshiro
authors.forename: Kazuo
authors.initials: K
authors.lastname: Shirouzu
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D001172:Arthritis, Rheumatoid; D005260:Female; D006801:Humans; D008477:Mediastinal Diseases / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D013950:Thymus Gland / Q000473:pathology