title: Pancreas-sparing duodenectomy in duodenal pathology: indications and results.
abstract: OBJECTIVE
  Pancreas sparing-duodenectomy is an organ-preserving surgical procedure suitable for patients with premalignant or early malignant lesions of the duodenum. The surgical technique is challenging due to the close anatomical relationship between the pancreas and the duodenum.
  
  
  METHODS
  All patients undergoing pancreas-sparing duodenectomy for benign or premalignant condition of the duodenum operated on between 1998 and 2001 were analyzed prospectively. The surgical technique, the hospital course, and complications are described.
  
  
  RESULTS
  A total of four patients underwent pancreas sparing-duodenectomy. Two patients experienced an uncomplicated postoperative course. In one patient, after completing the pancreas sparing-duodenectomy, the operation was converted to a Whipple procedure after the intraoperative diagnosis of malignant disease in the fresh frozen section. One patient had a complicated postoperative course with postoperative pancreatitis requiring several reoperations. At follow-up all patients are well, free of recurrence and alive.
  
  
  CONCLUSIONS
  Pancreas-sparing duodenectomy is a challenging surgical technique and requires excellent knowledge of the anatomy. Intraoperative fresh-frozen section is mandatory to exclude malignant disease. If performed for appropriate indications, pancreas sparing-duodenectomy offers the potential to preserve the anatomical gastrointestinal passage and the integrity of the pancreas.
authors.affiliation: Department of General Surgery, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
authors.forename: C F
authors.initials: CF
authors.lastname: Eisenberger
authors.forename: W T
authors.initials: WT
authors.lastname: Knoefel
authors.forename: M
authors.initials: M
authors.lastname: Peiper
authors.forename: E F
authors.initials: EF
authors.lastname: Yekebas
authors.forename: S B
authors.initials: SB
authors.lastname: Hosch
authors.forename: C
authors.initials: C
authors.lastname: Busch
authors.forename: J R
authors.initials: JR
authors.lastname: Izbicki
mesh_terms: D013505:Digestive System Surgical Procedures / Q000379:methods; D004379:Duodenal Neoplasms / Q000601:surgery*; D004386:Duodenum / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010179:Pancreas; D011446:Prospective Studies