title: Phylogeny of Firmicutes with special reference to Mycoplasma (Mollicutes) as inferred from phosphoglycerate kinase amino acid sequence data.
abstract: The phylogenetic position of the Mollicutes has been re-examined by using phosphoglycerate kinase (Pgk) amino acid sequences. Hitherto unpublished sequences from Mycoplasma mycoides subsp. mycoides, Mycoplasma hyopneumoniae and Spiroplasma citri were included in the analysis. Phylogenetic trees based on Pgk data indicated a monophyletic origin for the Mollicutes within the Firmicutes, whereas Bacilli (Firmicutes) and Clostridia (Firmicutes) appeared to be paraphyletic. With two exceptions, i.e. Thermotoga (Thermotogae) and Fusobacterium (Fusobacteria), which clustered within the Firmicutes, comparative analyses show that at a low taxonomic level, the resolved phylogenetic relationships that were inferred from both the Pgk protein and 16S rRNA gene sequence data are congruent.
authors.affiliation: University of Würzburg, Department of Bioinformatics, Biocenter, Am Hubland, 97074 Würzburg, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Wolf
authors.affiliation: University of Würzburg, Department of Bioinformatics, Biocenter, Am Hubland, 97074 Würzburg, Germany.
authors.forename: Tobias
authors.initials: T
authors.lastname: Müller
authors.affiliation: University of Würzburg, Department of Bioinformatics, Biocenter, Am Hubland, 97074 Würzburg, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Dandekar
authors.affiliation: Department of Molecular Virology, Immunology and Medical Genetics, Ohio State University, 2066 Graves Hall, 333 West 10th Avenue, Columbus, OH 43210, USA.
authors.forename: J Dennis
authors.initials: JD
authors.lastname: Pollack
mesh_terms: D000595:Amino Acid Sequence; D001419:Bacteria / Q000145:classification* / Q000201:enzymology / Q000235:genetics*; D019143:Evolution, Molecular; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D009174:Mycoplasma / Q000145:classification* / Q000201:enzymology / Q000235:genetics*; D010735:Phosphoglycerate Kinase / Q000235:genetics*; D010802:Phylogeny; D008973:Tenericutes / Q000145:classification* / Q000201:enzymology / Q000235:genetics*
chemical_list: D010735:Phosphoglycerate Kinase