title: [Effect of intraoperative using cell saver on blood sparing and its impact on coagulation function].
abstract: OBJECTIVE
  To observe the effectiveness of using cell saver (CS) during surgery on blood sparing and its impact on patient's hematology and coagulation function.
  
  
  METHODS
  One-hundred and thirty-eight patients undergoing elective surgery were recruited for intraoperative blood salvage using CS. Blood routine, blood chemistry and coagulation function were measured before surgery, after infusion of salvaged blood and postoperative day 1, respectively.
  
  
  RESULTS
  In total, 112,056 ml of packed red blood cells were collected, with a mean value of 812 ml per patient. The percentage of autologous blood transfusion volume to the total blood transfusion volume was from 48% to 89%. Allogenic blood transfusion rate was from 5% to 100%. Compared with the values before surgery, the hemoglobin concentration, platelet count, plasma total protein and fibrinogen concentration decreased significantly after the transfusion of salvaged blood and the first postoperative day (P < 0.05 or P < 0.01), while the prothrombin time was significantly prolonged (P < 0.05).
  
  
  CONCLUSIONS
  The use of CS during surgery can, to a certain extent, reduce the requirement of allogenic blood. However, reinfusion of large amount of salvaged blood may affect coagulation function.
authors.affiliation: Department of Anaesthesia, PUMC Hospital, CAMS and PUMC, Beijing 100730, China. xyg34@hotmail.com
authors.forename: Xiang-yang
authors.initials: XY
authors.lastname: Guo
authors.forename: He
authors.initials: H
authors.lastname: Duan
authors.forename: Jing-jie
authors.initials: JJ
authors.lastname: Wang
authors.forename: Ai-lun
authors.initials: AL
authors.lastname: Luo
authors.forename: Tie-hu
authors.initials: TH
authors.lastname: Ye
authors.forename: Yu-guang
authors.initials: YG
authors.lastname: Huang
authors.forename: Hong-zhi
authors.initials: HZ
authors.lastname: Ren
mesh_terms: D000328:Adult; D000368:Aged; D001780:Blood Coagulation Tests; D016063:Blood Loss, Surgical; D001804:Blood Transfusion, Autologous / Q000379:methods*; D001810:Blood Volume; D001026:Coronary Artery Bypass; D017558:Elective Surgical Procedures; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D011517:Prothrombin Time