A study of serum malondialdehyde and interleukin-6 levels in young women with dysmenorrhea in Taiwan.
The purpose of this study was to examine whether the symptoms of dysmenorrhea in young women were related to serum malondialdehyde (MDA) and interleukin-6 (IL-6) levels. Ninety-four non-smoking and non-drinking female subjects without serious disease from a nursing college in Taiwan were divided into two groups. Group 1 consisted of 51 subjects without dysmenorrheal, and Group 2 of 43 subjects with dysmenorrheal symptom. All subjects were provided informed consent. Results showed that the serum levels of MDA and of IL-6 were significantly different between the two groups (P < 0.05) and (P < 0.005), respectively. We conclude that the pathological mechanism of dysmenorrhea is mediated by oxidative stress caused by the action of cytokine.
Yeh
Mei-Ling
ML
National Taipei College of Nursing, No. 365, Ming-Te Road, Peitou 112, Taipei, Taiwan.
Chen
Hsing-Hsia
HH
So
Edmund C
EC
Liu
Chi-Feng
CF
D000328:Adult; D015415:Biomarkers / Q000097:blood*; D004412:Dysmenorrhea / Q000097:blood*; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D008315:Malondialdehyde / Q000097:blood*; D018384:Oxidative Stress / Q000502:physiology; D013624:Taiwan
D015415:Biomarkers; D015850:Interleukin-6; D008315:Malondialdehyde