External radiation therapy for endometrial carcinoma: the University Hospital of Ioannina experience.
OBJECTIVE
The aim of our study was to present the experience of our department in the treatment of endometrial cancer with postoperative external beam radiotherapy (EBRT) without intracavitary brachytherapy (BRT) and to evaluate the efficacy of such a method.


METHODS
We retrospectively retrieved the medical records of all patients with endometrial cancer treated with surgery and EBRT alone (median dose 50.0 Gy). Thirty-one women (median age: 67 years) of all clinical stages were reviewed and analyzed for recurrences (local or metastases) and late post-radiation side-effects.


RESULTS
Within a median follow-up of 17 months one patient developed local recurrence and four developed metastases. Overall survival was 97% and disease-free survival was 87%. Three women developed post-radiation colitis. No other treatment-related late side-effects were observed.


CONCLUSIONS
EBRT without BRT achieved an excellent local control in women with endometrial cancer although some of them were candidates for supplementary BRT.
Pakos
E E
EE
Department of Radiation Therapy, University Hospital of Ioannina, University of Ioannina, Medical School, Ioannina, Greece.
Gritzeli
S P
SP
Tsekeris
P G
PG
Pitouli
E J
EJ
Fintzou
M E
ME
D000230:Adenocarcinoma / Q000453:epidemiology / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D000368:Aged; D018196:Carcinoma, Adenosquamous / Q000453:epidemiology / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D016889:Endometrial Neoplasms / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006115:Greece / Q000453:epidemiology; D006784:Hospitals, Teaching; D006801:Humans; D007044:Hysterectomy; D008499:Medical Records; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D011184:Postoperative Period; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D016019:Survival Analysis