title: Frontal lobe seizures and uveitis associated with acute human parvovirus B19 infection.
abstract: We report a 5-year-old girl who developed repeated episodes of behavioral alterations shortly after human parvovirus B19 infection and uveitis. Video-electroencephalographic study demonstrated that these brief episodes were frontal lobe seizures. Seizures responded promptly to antiepilepsy medications. Further diagnostic testing did not reveal any rheumatologic disorders. Human parvovirus B19 infections in children are more commonly associated with febrile seizures and meningoencephalitis. Our case demonstrates that, rarely, it may be associated with the development of partial epilepsy.
authors.affiliation: Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Lucile Packard Children's Hospital at Stanford, California 94305-5235, USA.
authors.forename: David
authors.initials: D
authors.lastname: Hsu
authors.forename: Christy
authors.initials: C
authors.lastname: Sandborg
authors.forename: Jin S
authors.initials: JS
authors.lastname: Hahn
mesh_terms: D000208:Acute Disease; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D001921:Brain / Q000473:pathology; D002220:Carbamazepine / Q000627:therapeutic use; D002675:Child, Preschool; D004569:Electroencephalography; D016731:Erythema Infectiosum / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology*; D006801:Humans; D000077213:Lamotrigine; D008279:Magnetic Resonance Imaging; D009883:Ophthalmic Solutions; D016732:Parvovirus B19, Human / Q000302:isolation & purification; D010672:Phenytoin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D016133:Polymerase Chain Reaction; D011241:Prednisone / Q000627:therapeutic use; D012640:Seizures / Q000150:complications / Q000188:drug therapy / Q000821:virology*; D014227:Triazines / Q000627:therapeutic use; D014605:Uveitis / Q000150:complications / Q000188:drug therapy / Q000821:virology*; D014741:Video Recording
chemical_list: D000893:Anti-Inflammatory Agents; D000927:Anticonvulsants; D009883:Ophthalmic Solutions; D014227:Triazines; D002220:Carbamazepine; D010672:Phenytoin; C043114:fosphenytoin; D000077213:Lamotrigine; D011241:Prednisone