Effect of Helicteres isora root extracts on glucose tolerance in glucose-induced hyperglycemic rats.
The ethanol, ethyl acetate and butanol extracts of Helicteres isora root showed significant oral hypoglycemic activity on glucose loaded rats at a dose of 250 mg/kg. The butanol extract showed maximum antihyperglycemic activity and effect being comparable to that of glibenclamide.
Venkatesh
Sama
S
G. Pulla Reddy College of Pharmacy, Mehdipatnam, Hyderabad 500 028, India. venkateshsama@hotmail.com
Dayanand Reddy
G
G
Reddy
Y S R
YS
Sathyavathy
D
D
Madhava Reddy
B
B
D000818:Animals; D001786:Blood Glucose / Q000187:drug effects; D003924:Diabetes Mellitus, Type 2 / Q000139:chemically induced / Q000517:prevention & control*; D005947:Glucose / Q000494:pharmacology; D005951:Glucose Tolerance Test; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D019660:Malvaceae; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018517:Plant Roots; D051381:Rats; D017208:Rats, Wistar
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D005947:Glucose