Stenotrophomonas maltophilia: the significance and role as a nosocomial pathogen.
Stenotrophomonas maltophilia is a significant pathogen that primarily affects patients with co-morbid illnesses, usually malignancies, who have been hospitalized for prolonged periods and received broad-spectrum antibiotic therapy. The organism has been associated with an expanding spectrum of clinical manifestations associated with high case to fatality ratios. Therapy of these infections presents a significant challenge both for the clinician and the microbiologists because of its high-level antibiotic resistance to most of the currently used agents and methodological difficulties in susceptibility testing with this organism.
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Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Gazi University, Besevler, Ankara, Turkey. esins@gazi.edu.tr
D000890:Anti-Infective Agents / Q000494:pharmacology; D003428:Cross Infection / Q000188:drug therapy*; D004352:Drug Resistance, Microbial; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy*; D006801:Humans; D020615:Stenotrophomonas maltophilia / Q000187:drug effects / Q000302:isolation & purification*; D014421:Turkey
D000890:Anti-Infective Agents