[Clinical observation on treatment of SARS with combination of chaihu droplet pill and huoxiang zhengqi droplet pill].
OBJECTIVE
To observe the effect of combination treatment with Chaihu Droplet pill (CHDP) and Huoxiang Zhengqi Droplet pill (HZDP) in treating severe acute respiratory syndrome (SARS) in early stage.


METHODS
Twenty-two patients of SARS were randomly selected and paired according to such controlling factors as age, sex and profession into 11 couples. To them all symptomatic treatment was applied, combined CHDP and HZDP (CH-HZ) was given additionally to one of each couple randomly. The treatment was lasted for 13 days to investigate the changes of the clinical indexes such as creatine kinase (CK), lactate dehydogenase (LDH) and serum sodium levels.


RESULTS
Early applying of CH-HZ treatment showed good effects in improving CK, LDH, oxygenation index and absolute value of neutrophils, and could reduce the daily maximal dosage of glucocorticoid needed for SARS patients.


CONCLUSIONS
Early application of CH-HZ treatment in treating SARS could alleviate the injury in lung of SARS patients and the neutrophil dependent inflammatory reaction, and reduce the dosage of glucocorticoid used.
Li
Hai
H
Tianjin Municipal Hospital of Infectious Diseases, Tianjin 300192. lihaicp@hotmail.com
Lu
Cheng-zhen
CZ
Tang
Ke-cheng
KC
D000328:Adult; D003402:Creatine Kinase / Q000097:blood; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000009:adverse effects; D008875:Middle Aged; D008517:Phytotherapy; D012254:Ribavirin / Q000627:therapeutic use; D045169:Severe Acute Respiratory Syndrome / Q000097:blood / Q000188:drug therapy*
D004365:Drugs, Chinese Herbal; D012254:Ribavirin; D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase; D008775:Methylprednisolone