title: Treatment with epoprostenol of pulmonary arterial hypertension following mitral valve replacement for mitral stenosis.
abstract: Pulmonary hypertension frequently complicates mitral stenosis. Increased pulmonary artery pressure results from raised left atrial pressure, pulmonary arteriolar constriction, and obliterative changes in the pulmonary vascular bed, and usually responds to surgical relief of mitral stenosis. However, severe pulmonary hypertension may persist after surgical treatment of mitral stenosis. We describe a patient whose severe pulmonary hypertension following mitral valve replacement was treated successfully with continuous intravenous epoprostenol.
authors.affiliation: Department of Medicine, LDS Hospital and the University of Utah School of Medicine, Salt Lake City, USA. ldgellio@ihc.com
authors.forename: C G
authors.initials: CG
authors.lastname: Elliott
authors.forename: H I
authors.initials: HI
authors.lastname: Palevsky
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D011464:Epoprostenol / Q000627:therapeutic use*; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000209:etiology; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000601:surgery*; D011183:Postoperative Complications / Q000188:drug therapy* / Q000209:etiology
chemical_list: D000959:Antihypertensive Agents; D011464:Epoprostenol