title: [Exploration on the relationship between positive antisperm antibody and nitric oxide level of infertile patients and on integrative Chinese and Western medicine treatment].
abstract: OBJECTIVE
  To study the relationship between the positive antisperm antibody (AsAb) and nitric oxide (NO) content in blood of infertile patients and the therapeutic effect of integrative Chinese and western medicine (ICWM) treatment on the disease.
  
  
  METHODS
  Infertile patients, 75 of AsAb positive and 68 of AsAb negative were selected to observe the mature partuient rate and abortion rate. Serum NO level were measured before treatment to observe the relationship between NO and positive AsAb. Patients were treated with ICWM and followed-up for five years.
  
  
  RESULTS
  Mean value of serum NO in patients with positive AsAb was significantly higher than that in fertile women, and there was no significant difference between patients with negative AsAb and fertile women (P < 0.01). In the 5 years after treatment, the mature partuient rate between the two groups showed insignificant difference (P > 0.05).
  
  
  CONCLUSIONS
  AsAb positive and NO level abnormal may interfere mutually, to intervent the reproductive process. ICWM therapy could effectively regulate auto-immunity and endocrine function, and make the infertile patients obtain satisfactory efficacy.
authors.affiliation: Second Affiliated Hospital of Jiangxi Medical College, Nanchang 330006.
authors.forename: Ding-ling
authors.initials: DL
authors.lastname: Liao
authors.forename: Li-qun
authors.initials: LQ
authors.lastname: Yu
authors.forename: Hua
authors.initials: H
authors.lastname: Xin
mesh_terms: D000328:Adult; D000906:Antibodies / Q000097:blood*; D003907:Dexamethasone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use; D006801:Humans; D007247:Infertility, Female / Q000097:blood / Q000188:drug therapy* / Q000276:immunology; D008297:Male; D009569:Nitric Oxide / Q000097:blood*; D008517:Phytotherapy; D013094:Spermatozoa / Q000276:immunology*
chemical_list: D000906:Antibodies; D004365:Drugs, Chinese Herbal; D005300:Fertility Agents, Female; D009569:Nitric Oxide; D003907:Dexamethasone