title: Optimization of dose and dose regimen of biapenem based on pharmacokinetic and pharmacodynamic analysis.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Miyazaki
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use; D004334:Drug Administration Schedule; D006801:Humans; D051379:Mice; D008826:Microbial Sensitivity Tests / Q000592:standards; D011552:Pseudomonas Infections / Q000188:drug therapy* / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D013845:Thienamycins / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use; D013848:Thigh / Q000382:microbiology; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D013845:Thienamycins; C065257:biapenem