title: It's "juxta" potassium channel!
abstract: Neuronal excitability depends on the appropriate expression and localization of ion channels. Juxtaparanodal Kv1 channels have been used as a model to study the role of neuroglial interactions in regulating the expression and localization of channels in myelinated axons. Recent advances in our understanding of the composition of juxtaparanodal Kv1 channel protein complexes as well as the cellular and molecular mechanisms underlying their localization at juxtaparanodes are discussed.
authors.affiliation: Department of Neuroscience, University of Connecticut Health Center, Farmington, 06032, USA. Rasband@uchc.edu
authors.forename: Matthew N
authors.initials: MN
authors.lastname: Rasband
mesh_terms: D000818:Animals; D001369:Axons / Q000502:physiology*; D015816:Cell Adhesion Molecules, Neuronal / Q000502:physiology; D002450:Cell Communication / Q000502:physiology; D002462:Cell Membrane / Q000502:physiology*; D058969:Contactin 2; D006801:Humans; D008565:Membrane Proteins / Q000502:physiology; D051379:Mice; D008959:Models, Neurological; D009413:Nerve Fibers, Myelinated / Q000502:physiology*; D009419:Nerve Tissue Proteins / Q000502:physiology; D009457:Neuroglia / Q000502:physiology; D009474:Neurons / Q000502:physiology; D024642:Potassium Channels, Voltage-Gated / Q000145:classification / Q000502:physiology*; D011901:Ranvier's Nodes / Q000502:physiology*
chemical_list: C548674:CNTN2 protein, human; C403049:CNTNAP2 protein, human; D015816:Cell Adhesion Molecules, Neuronal; C548675:Cntn2 protein, mouse; D058969:Contactin 2; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins; D024642:Potassium Channels, Voltage-Gated