A rare case of idiopathic hypereosinophilic syndrome involving the oral cavity associated with the esophagus and gastrointestinal tract.
We report the rare case of HES involving oral cavity associated with esophagus, and gastrointestinal tract, which we succeeded in diagnosing precisely through a biopsy specimen obtained from the lip. A 64-year-old man had dysphagia, swelling of the oral mucosa and the posterior cervical muscles, accompanied by an abdominal pain and diarrhea. Peripheral blood cell count showed marked eosinophilia. Computed tomography showed thickening of posterior wall of the pharynx, esophagus, and gastrointestinal tract. Histologic specimen obtained from the lower lip demonstrated a moderate infiltration of eosinophils. His clinical condition was improved by oral prednisolone therapy.
Watanabe
Michi
M
Department of Internal Medicine, Fukuoka City Hospital, Fukuoka.
Matsui
Noriaki
N
Hamada
Syuji
S
Ohuchi
Jiro
J
Shimohashi
Naoya
N
Katoh
Masaki
M
Kunisaki
Makoto
M
Tanabe
Yuichi
Y
Hashimoto
Toshihiko
T
Yoshida
Kisaku
K
Uryu
Hideoki
H
Yamamoto
Hidetaka
H
D003680:Deglutition Disorders / Q000209:etiology; D004947:Esophagus / Q000473:pathology*; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D007421:Intestine, Small / Q000473:pathology*; D008046:Lip / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology*; D011239:Prednisolone / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
D005938:Glucocorticoids; D011239:Prednisolone