title: [Inflammatory colitis and chronic granulomatous disease, a steroid-dependent case report].
abstract: Chronic granulomatous disease may lead to inflammatory bowel disease with endoscopic and histological aspects similar to that observed in patients with Crohn's disease. Inflammatory symptoms are generally controlled by steroids, but resistant forms may need total colectomy. Therapeutic strategy in steroid-dependent cases is not yet established. We report here the case of a patient with chronic granulomatous enteritis dependent on steroids at a daily dose of 20 mg. Azathioprine made it possible to withdraw steroid therapy without relapse over twenty Months and without infectious complication during the follow up.
authors.affiliation: Service d'Hépato-Gastroentérologie, Centre Hospitalier Intercommunal de Créteil.
authors.forename: David
authors.initials: D
authors.lastname: Zanditenas
authors.forename: Hervé
authors.initials: H
authors.lastname: Hagège
authors.forename: Isabelle
authors.initials: I
authors.lastname: Rosa
authors.forename: Philippe
authors.initials: P
authors.lastname: Cattan
authors.forename: Sylvie
authors.initials: S
authors.lastname: Ratel-Saby
authors.forename: Thierry
authors.initials: T
authors.lastname: Lons
authors.forename: Michel
authors.initials: M
authors.lastname: Chousterman
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use; D003092:Colitis / Q000188:drug therapy* / Q000209:etiology; D006105:Granulomatous Disease, Chronic / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D012074:Remission Induction / Q000379:methods
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D001379:Azathioprine