title: [Effects on neuronal ultrastructure and nervous system of monkey after selective cerebral profound hypothermia and blood flow occlusion].
abstract: OBJECTIVE
  To study the effects of deep hypothermia on the neuronal ultrastructure and nervous system of monkey after selective cerebral profound hypothermia and blood flow occlusion.
  
  
  METHODS
  Brain-local extracorporeal circulation was established by right internal carotid artery deep hypothermic perfusion and homolateral external jugular vein backflow, brain blood flow was recovered from circulatory arrest 60 - 80 minutes late and monkey came back naturally.
  
  
  RESULTS
  In all 7 monkeys, 5 were succeeded in being build up the models except for 2 because of technic problems, and 4 of them lived up for ever. The function of nervous system grade, essential organ and neuronal ultrastructure were normal.
  
  
  CONCLUSIONS
  Selective cerebral profound hypothermia can increase the ability of brain to endure hypovolemia and hypoxidosis and prolong the time of blood flow occlusion.
authors.affiliation: Department of Neurosurgery, the Second Affiliated Hospital of Kunming Medical College, Kunming 650101, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Xu
authors.forename: Ji-yao
authors.initials: JY
authors.lastname: Jiang
authors.forename: Peng-fan
authors.initials: PF
authors.lastname: Yang
authors.forename: Yong-jun
authors.initials: YJ
authors.lastname: Gao
authors.forename: Shao-long
authors.initials: SL
authors.lastname: Fang
authors.forename: Deng-li
authors.initials: DL
authors.lastname: Fu
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000209:etiology / Q000473:pathology / Q000503:physiopathology / Q000517:prevention & control*; D002560:Cerebrovascular Circulation; D004195:Disease Models, Animal; D005112:Extracorporeal Circulation / Q000009:adverse effects; D005260:Female; D000882:Haplorhini; D007036:Hypothermia, Induced; D008297:Male; D013997:Time Factors