Interstitial growth of bone revisited.
The distance between two or more metallic implants placed within the same flat bones (mandible, nasal, frontal, hyoplastron, hypoplastron) of young pigs, rabbits, and turtles followed by means of serial radiographs, remained the same for periods as long as 546 days. Thus, it is concluded that there is no interstitial growth. In 1743, Duhamel demonstrated that long bones grow at their ends and that there is no interstitial growth. This report is unique in that it demonstrates by use of radiopaque implants and serial radiographs that there is no interstitial growth of flat bones, which grow by apposition and resorption, and not endochondrally, such as occurs in long bones.
Sarnat
Bernard G
BG
Section of Oral Biology, School of Dentistry and Division of Plastic Surgery, School of Medicine, University of California and Division of Plastic Surgery, Cedars-Sinai Medical Center, Los Angeles, California, USA. BSarnat@earthlink.net
D000818:Animals; D001846:Bone Development / Q000502:physiology*; D002508:Cephalometry / Q000295:instrumentation; D018483:Diaphyses / Q000254:growth & development*; D005260:Female; D005624:Frontal Bone / Q000000981:diagnostic imaging / Q000254:growth & development; D020007:Implants, Experimental; D008334:Mandible / Q000000981:diagnostic imaging / Q000254:growth & development; D009295:Nasal Bone / Q000000981:diagnostic imaging / Q000254:growth & development; D011817:Rabbits; D011859:Radiography; D013552:Swine; D014426:Turtles