title: A blue-to-red energy-transfer thymidine analogue that functions in DNA.
abstract: The thymidine analogue 1 is a blue-to-red energy transfer cassette designed to absorb UV light in the 300 nm region and emit it as fluorescence at around 520 nm. When incorporated into DNA, the fluorescence intensity of this modified nucleobase is not significantly reduced by the surrounding structure in the oligonucleotides. [structure--see text]
authors.affiliation: Department of Chemistry, Texas A & M University, Box 30012, College Station, TX 77842-3012, USA.
authors.forename: Guan-Sheng
authors.initials: GS
authors.lastname: Jiao
authors.forename: Taeg Gyum
authors.initials: TG
authors.lastname: Kim
authors.forename: Michael R
authors.initials: MR
authors.lastname: Topp
authors.forename: Kevin
authors.initials: K
authors.lastname: Burgess
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000737:chemistry* / Q000235:genetics; D004735:Energy Transfer; D015394:Molecular Structure; D009838:Oligodeoxyribonucleotides / Q000737:chemistry / Q000235:genetics; D013050:Spectrometry, Fluorescence; D013936:Thymidine / Q000031:analogs & derivatives* / Q000737:chemistry*
chemical_list: D009838:Oligodeoxyribonucleotides; D004247:DNA; D013936:Thymidine