title: [The use of nebivolol for the treatment of hypertension in patients with osteoarthrosis].
abstract: Nebivolol (5 mg/day) was given for 3 months to 20 patients with essential hypertension and osteoarthrosis treated with diclofenac and to 20 other patients with essential hypertension. After 3 months lowering of blood pressure, decreases of components of 24-hour blood pressure profile, improvements of signs of left ventricular hypertrophy occurred in both groups. There were no significant differences between changes of parameters studied between 2 groups. Thus diclofenac (nonselective cyclooxygenase inhibitor) did not attenuate antihypertensive effect of nebivolol and its action on left ventricular hypertrophy.
authors.affiliation: St-Petersburg Medical Academy of Postgraduate Medical Education; ul Kirochnaya 41, 193015 St-Petersburg, Russia.
authors.forename: V I
authors.initials: VI
authors.lastname: Mazurov
authors.forename: V V
authors.initials: VV
authors.lastname: Rassokhin
authors.forename: M S
authors.initials: MS
authors.lastname: Shostak
mesh_terms: D000959:Antihypertensive Agents; D001578:Benzopyrans; D004983:Ethanolamines; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D000068577:Nebivolol; D010003:Osteoarthritis
chemical_list: D000959:Antihypertensive Agents; D001578:Benzopyrans; D004983:Ethanolamines; D000068577:Nebivolol