title: [Changes of the immune status of children with relapsing herpetic stomatitis, suffering from allergic diseases, during licopide treatment].
abstract: The efficiency of licopide in combination with traditional treatment was evaluated in 59 children aged 1-14 years suffering from allergic diseases and relapsing herpetic stomatitis. Immunological studies were carried out before and after a course of therapy: local oral immunity, cellular immunity (in the blast transformation test with phytohemagglutinin), lymphocyte populations and subpopulations, humoral immunity values (IgA, IgM, IgG, and IgE), and C3 complement component were evaluated. The results indicate that licopide in complex with traditional methods normalized the immunological values, had a favorable impact on the course of relapsing herpetic stomatitis, and led to a stable remission of allergic diseases (p<0.001).
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Kuznetsova
authors.forename: I I
authors.initials: II
authors.lastname: Balabolkin
authors.forename: N I
authors.initials: NI
authors.lastname: Kuznetsova
mesh_terms: D000119:Acetylmuramyl-Alanyl-Isoglutamine / Q000031:analogs & derivatives* / Q000494:pharmacology* / Q000627:therapeutic use; D000276:Adjuvants, Immunologic / Q000494:pharmacology* / Q000627:therapeutic use; D000293:Adolescent; D000917:Antibody Formation / Q000187:drug effects; D001249:Asthma / Q000150:complications* / Q000276:immunology; D029481:Bronchitis, Chronic / Q000150:complications* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007223:Infant; D012008:Recurrence; D013283:Stomatitis, Herpetic / Q000150:complications* / Q000188:drug therapy / Q000276:immunology*; D016896:Treatment Outcome
chemical_list: D000276:Adjuvants, Immunologic; C089161:glikopin; D000119:Acetylmuramyl-Alanyl-Isoglutamine