title: Large spontaneous coronary artery dissections-a study of three cases, literature review, and possible therapeutic strategies.
abstract: Spontaneous coronary artery dissection is rare, but is now being increasingly recognized as a prominent cause of acute ischemic coronary events occurring usually in relatively young patients, predominantly females. The authors describe the clinical course of 3 patients (1 woman) in whom large spontaneous coronary artery dissections developed. All had diverse clinical presentations;1 presenting with heart failure, the second with post-myocardial infarction angina, and the third with syncope. The second patient underwent coronary angioplasty with multiple overlapping stents while in the other two, it was the considered opinion to continue aggressive medical therapy. The 1-year follow-up was uneventful in all 3 patients. The risk factors ascertained in our patients were diabetes mellitus, smoking, and hypertension.
authors.affiliation: Departments of Cardiology and Nuclear Medicine, Institute of Medical Education and Research, Chandigarh, India. puneet_verma@hotmail.com
authors.forename: Puneet K
authors.initials: PK
authors.lastname: Verma
authors.forename: Manjinder S
authors.initials: MS
authors.lastname: Sandhu
authors.forename: Bhagwant R
authors.initials: BR
authors.lastname: Mittal
authors.forename: Naveen
authors.initials: N
authors.lastname: Aggarwal
authors.forename: Arvind
authors.initials: A
authors.lastname: Kumar
authors.forename: Manas
authors.initials: M
authors.lastname: Mayank
authors.forename: Anish
authors.initials: A
authors.lastname: Bhattacharya
authors.forename: Ram K
authors.initials: RK
authors.lastname: Anand
authors.forename: Anil
authors.initials: A
authors.lastname: Grover
mesh_terms: D000328:Adult; D000784:Aortic Dissection / Q000175:diagnosis* / Q000628:therapy; D003323:Coronary Aneurysm / Q000175:diagnosis* / Q000628:therapy; D017023:Coronary Angiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D015899:Tomography, Emission-Computed, Single-Photon