Antioxidative constituents from the leaves of Hypericum styphelioides.
Two new compounds have been isolated from the leaves of Hypericum styphelioides. Their structures have been established on the basis of mass spectrometry and 2D NMR techniques as 1,3,5-trihydroxy-2-(2',2'-dimethyl-4'-isopropenyl)cyclopentanylxanthone (1) and 3,5-dihydroxybenzophenon-4-beta-d-glucoside (2). Known compounds 5-O-demethylpaxanthonin (3) and 3-geranyl-1-(3-methylbutanoyl)phloroglucinol (4) were also isolated and characterized. Compounds 1-4 were evaluated for their antioxidative properties in Trolox equivalent antioxidant activity (TEAC) and chemiluminescence (CL) assays.
Gamiotea-Turro
Daylin
D
Center of Pharmaceutical Chemistry (CQF), 200 & 21, Atabey, Playa, PO Box 16042, Apartado 6990, La Habana, Cuba.
Cuesta-Rubio
Osmany
O
Prieto-González
Sylvia
S
De Simone
Francesco
F
Passi
Siro
S
Rastrelli
Luca
L
D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001577:Benzophenones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D003462:Cuba; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020902:Hypericum / Q000737:chemistry*; D008163:Luminescent Measurements; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010084:Oxidation-Reduction; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013237:Stereoisomerism; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
C487243:1,3,5-trihydroxy-2-(2',2'-dimethyl-4'-isopropenyl)cyclopentanylxanthone; C487244:3,5-dihydroxybenzophenon-4-glucoside; D000975:Antioxidants; D001577:Benzophenones; D005960:Glucosides; D044004:Xanthones