title: Encephalopathy secondary to imipenem therapy.
abstract: We describe the case of an 84-year-old woman who developed a confusional state and suffered from a generalized tonic-clonic seizure while she was treated with imipenem, a beta-lactam antibiotic. Focal and generalized epileptiform discharges and a photoparoxysmal response were prominent with transient changes on the EEG.
authors.affiliation: Department of Clinical Neurophysiology, Hospital Universitario "Marqués de Valdecilla", Santander, Cantabria, Spain. jlfernandez@humv.es
authors.forename: J L
authors.initials: JL
authors.lastname: Fernández-Torre
authors.forename: M
authors.initials: M
authors.lastname: Velasco
authors.forename: R
authors.initials: R
authors.lastname: Gutiérrez
authors.forename: M
authors.initials: M
authors.lastname: Fernández-Sampedro
mesh_terms: D000151:Acinetobacter Infections / Q000097:blood / Q000188:drug therapy; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use; D004569:Electroencephalography; D004830:Epilepsy, Tonic-Clonic / Q000097:blood / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D006801:Humans; D015378:Imipenem / Q000009:adverse effects* / Q000627:therapeutic use*; D013203:Staphylococcal Infections / Q000097:blood / Q000188:drug therapy; D014552:Urinary Tract Infections / Q000097:blood / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D015378:Imipenem