Efficacy of topical treatment with aescin + essential phospholipids gel in a microcirculatory model of venous insufficiency.
The aim of this efficacy study was to evaluate the effects of topical aescin + essential phospholipids gel in a histamine model of acute microangiopathy, comparable to microangiopathy observed in chronic venous disease.
Belcaro
G
G
Irvine2 Vascular Laboratory, Department of Biomedical Sciences, G. D'Annunzio University, Italy. cardres@pe.abol.it
Cesarone
M R
MR
Dugall
M
M
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D004338:Drug Combinations; D004928:Escin / Q000008:administration & dosage*; D005260:Female; D005782:Gels; D006632:Histamine / Q000494:pharmacology; D006801:Humans; D007478:Iontophoresis; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged; D010713:Phosphatidylcholines / Q000008:administration & dosage*; D012039:Regional Blood Flow / Q000187:drug effects; D012867:Skin / Q000098:blood supply*; D014689:Venous Insufficiency / Q000188:drug therapy* / Q000503:physiopathology
D004338:Drug Combinations; D005782:Gels; D010713:Phosphatidylcholines; C011246:essential 303 forte; D004928:Escin; D006632:Histamine