[The clinical application on composite graft of acellular allo-dermal matrix and auto-microskin on escharectomy after deep burns].
OBJECTIVE
To present the clinical application of composite graft of acellular allo-dermis matrix (ADM) with thin auto-microskin on burn wound.


METHODS
8 inpatients with 18 full thickness skin burn wounds were transplanted with allo-ADM after eschar was excised, then the auto-microskin and allo-human skin were covered on the area of the matrix, the wound where no allo-ADM grafting were covered as control groups only with auto-microskin and allo-human skin. The area of donor to wound is 1:5 - 1:8.


RESULTS
Survived rate of 18 pieces composite skin that allo-ADM with auto-microskin were grafted were 94%. After following up for 3 to 13 months, the skins of complex grifting had well elastic and smooth texture compared to auto-microskin grafted, they appeared less cicatrisation and ulceration. 3 months after operation, it was indicated by histological examination that tightknit the epithelial-dermal conjunction and epidermal papilla structure could be identified in the allo-ADM skin and there were orderly collagenous fibres, but scar skin structure was observed in that auto-microskin grifted area.


CONCLUSIONS
The graft effectiveness of allo-ADM and auto-microskin was better than that of auto-microskin, and this method could be used on major deep burn wound healing.
Pan
Yun-chuan
YC
Department of Plastic Surgery and Burns, Hainan Provincial Hospital, Haikou 570311, China.
Xu
Jia-qin
JQ
Chen
Yan-kun
YK
Li
Song-ling
SL
Chen
Si-huan
SH
Wu
Duo-neng
DN
Zeng
De-bin
DB
Liang
Zun-hong
ZH
D000328:Adult; D002056:Burns / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016038:Skin Transplantation / Q000379:methods*; D014019:Tissue Donors; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous; D016896:Treatment Outcome