[Cardiometabolic therapy of ischemic heart disease].
A total of 59 patients suffering from ischemic heart disease with effort angina (functional classes II-IV) entered the study. Of them, 29 patients received antianginal drugs and 10-day courses of a combination of drugs with membran-oprotective properties (MPD); 30 patients received antianginal drugs alone. Blood levels of lipid peroxidation products, lipid structure of erythrocytic membrane, exercise tolerance were studied before and after the treatment. MPD therapy was associated with lower activity of lipid peroxidation, stabilization of cell membrane structure and greater exercise tolerance due to more effective cardiac performance.
Vasil'ev
A P
AP
Strel'tsova
N N
NN
Senatorov
Iu N
IuN
D000787:Angina Pectoris / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D004910:Erythrocyte Membrane / Q000187:drug effects; D017079:Exercise Tolerance; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D017202:Myocardial Ischemia / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000008:administration & dosage*
D014665:Vasodilator Agents