title: Contrast-enhanced, wide-band phase-inversion power Doppler imaging of hepatic focal nodular hyperplasia.
abstract: OBJECTIVE
  To determine whether examination of hepatic focal nodular hyperplasia by wide-band, phase-inversion sonography offers any advantages over power and color Doppler sonography in the depiction of specific characteristics of these pathologies.
  
  
  METHODS
  Twenty-six patients were examined. The presence of focal nodular hyperplasia was confirmed by ultrasound-guided biopsy, surgical resection, dynamic helical computed tomography or magnetic resonance. All patients, prior to enhanced sonography, had undergone B-mode gray-scale sonography, color Doppler, and power Doppler examinations. After injection of 2.5 g of Levovist intravenously, analysis of the contrast agent arrival was performed by wide-band, phase-inversion power Doppler sonography.
  
  
  RESULTS
  The B-mode gray-scale sonography, color and power Doppler sonography were non-specific for focal nodular hyperplasia in 14 cases in our examination. However based on the wide-band, phase-inversion power Doppler sonography findings all patients with focal nodular hyperplasia were diagnosed. All typical anatomic features of focal nodular hyperplasia such as "star sign" or "spoke-wheel" pattern were clearly visible. In 3 cases, computed tomography and magnetic resonance imaging had failed to disclose pathology while phase-inversion sonographic images were completely suggestive which was later finally confirmed by histologic examination.
  
  
  CONCLUSIONS
  Our data demonstrate the usefulness of wide-band, phase-inversion power Doppler sonography in the differential diagnosis of hepatic focal nodular hyperplasia by visualizing all characteristic anatomic details.
authors.affiliation: Department of Radiology, Medical University of Bialystok, Poland.
authors.forename: Jacek
authors.initials: J
authors.lastname: Janica
authors.forename: Serwatka
authors.initials: S
authors.lastname: Wojciech
authors.forename: Slawomir
authors.initials: S
authors.lastname: Dolorzycki
authors.forename: Jerzy
authors.initials: J
authors.lastname: Polakow
authors.forename: Jerzy
authors.initials: J
authors.lastname: Walecki
authors.forename: Jerzy Robert
authors.initials: JR
authors.lastname: Ladny
authors.forename: Wiktor
authors.initials: W
authors.lastname: Laszewicz
mesh_terms: D000328:Adult; D003287:Contrast Media; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000000981:diagnostic imaging*; D006801:Humans; D008099:Liver / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D018608:Ultrasonography, Doppler
chemical_list: D003287:Contrast Media