title: Bromocriptine treatment of prolactinoma restores growth hormone secretion and causes catch-up growth in a prepubertal child.
abstract: A 13-year-old Japanese boy with pituitary prolactinoma whose growth had been retarded for more than 2 years was treated with bromocriptine alone for 140 weeks. After treatment, the serum level of prolactin, which was 1200 ng/ml before treatment, returned to normal and the pituitary tumour seen on the initial brain MRI had rapidly decreased in size after 16 weeks of treatment. Thereafter, his height improved (from -2.1 to -1.7 SDS).
  
  
  CONCLUSIONS
  the favourable response obtained in this patient implies that bromocriptine monotherapy can be an effective first-line treatment for children with prolactinoma.
authors.affiliation: Department of Paediatrics, Dokkyo University School of Medicine, 2-1-50 Minami-koshigaya, Koshigaya, Saitama, Japan.
authors.forename: Satoru
authors.initials: S
authors.lastname: Sakazume
authors.forename: Kazuo
authors.initials: K
authors.lastname: Obata
authors.forename: Etsurou
authors.initials: E
authors.lastname: Takahashi
authors.forename: Atsunori
authors.initials: A
authors.lastname: Yoshino
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Murakami
authors.forename: Ryoich
authors.initials: R
authors.lastname: Sakuta
authors.forename: Takayasu
authors.initials: T
authors.lastname: Murai
authors.forename: Toshiro
authors.initials: T
authors.lastname: Nagai
mesh_terms: D000293:Adolescent; D001971:Bromocriptine / Q000627:therapeutic use*; D018491:Dopamine Agonists / Q000627:therapeutic use*; D006130:Growth Disorders / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D006966:Hyperprolactinemia / Q000150:complications / Q000188:drug therapy*; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications / Q000188:drug therapy*; D015175:Prolactinoma / Q000150:complications / Q000188:drug therapy*
chemical_list: D018491:Dopamine Agonists; D001971:Bromocriptine