title: Multidetector row CT angiography of the abdominal aorta and lower extremities in patients with peripheral arterial occlusive disease: diagnostic accuracy and interobserver agreement.
abstract: OBJECTIVE
  To evaluate the accuracy of four channel multidetector row CT angiography (MDCTA) of the abdominal aorta and lower extremities arteries compared with digital subtraction angiography (DSA).
  
  
  METHODS
  In our prospective study 42 patients with peripheral vascular occlusive disease (27 M, 15 F, age range 40-79 years) underwent MDCTA and DSA within 5 days. Images were blindly interpreted by two radiologists. Maximum intensity projections (MIP), multiplanar (MPR) reformations, three-dimensional (3D) reconstructions as well as axial images were available for analysis of MDCTA. DSA were analyzed on hard copies.
  
  
  RESULTS
  Overall sensitivity and specificity of MDCTA were 93 and 95%, respectively, with positive and negative predictive values of 90 and 97%. Overall diagnostic accuracy was 94%. Normal arterial segments and 100% occlusions were correctly identified in all cases by MDCTA. Moderately stenotic segments interpretation in the calves appeared to be more controversial, but no statistical difference in accuracy of MDCTA in the infrapopliteal district arteries was noted with respect to accuracy in the more proximal arterial bed. Good to excellent interobserver and intraobserver agreement were observed, with k values greater than 0.80.
  
  
  CONCLUSIONS
  MDCTA of the abdominal aorta and lower extremities is an accurate imaging modality in clinical practice when compared with DSA.
authors.affiliation: Department of Surgery, University Federico II, 5, Via Pansini, 80131 Naples, Italy. maurizio.romano@mailcmn.area.na.cnr.it
authors.forename: Maurizio
authors.initials: M
authors.lastname: Romano
authors.forename: Pier Paolo
authors.initials: PP
authors.lastname: Mainenti
authors.forename: Massimo
authors.initials: M
authors.lastname: Imbriaco
authors.forename: Bruno
authors.initials: B
authors.lastname: Amato
authors.forename: Karim
authors.initials: K
authors.lastname: Markabaoui
authors.forename: Oscar
authors.initials: O
authors.lastname: Tamburrini
authors.forename: Marco
authors.initials: M
authors.lastname: Salvatore
mesh_terms: D000328:Adult; D000368:Aged; D015901:Angiography, Digital Subtraction / Q000379:methods*; D001012:Aorta, Abdominal / Q000000981:diagnostic imaging*; D001157:Arterial Occlusive Diseases / Q000175:diagnosis*; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D035002:Lower Extremity / Q000098:blood supply / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D016491:Peripheral Vascular Diseases / Q000175:diagnosis*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*