Candida parapsilosis endocarditis that emerged 2 years after abdominal surgery.
A 22-year-old man was hospitalized after 3 months of persistent fever and malaise. He had undergone abdominal surgery 24 months before admission. Echocardiography demonstrated two mobile pedunculated masses in the right ventricle. Multiple blood cultures were positive for Candida parapsilosis. After 4 weeks of miconazole treatment, the two masses were excised via a right atriotomy incision and the transtricuspid value approach. Histological examination revealed that they were fungal vegetation. Antifungal agents were continued for 1 year after surgery. The patient has remained well with no further symptoms for 3 years. This case suggests the necessity for careful evaluation of past history to avoid diagnostic delay in fungal endocarditis.
Tonomo
Kazumi
K
Department of Internal Medicine, Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan.
Tsujino
Takeshi
T
Fujioka
Yoshio
Y
Nakao
Shinji
S
Yao
Hideki
H
Yasoshima
Hitoshi
H
Kubota
Akira
A
Iwasaki
Tadaaki
T
Ohyanagi
Mitsumasa
M
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000175:diagnosis* / Q000188:drug therapy; D003428:Cross Infection / Q000175:diagnosis / Q000188:drug therapy; D004697:Endocarditis, Bacterial / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D008825:Miconazole / Q000627:therapeutic use; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D013997:Time Factors; D014463:Ultrasonography
D000935:Antifungal Agents; D008825:Miconazole