title: Conservative treatment in noninvasive breast cancer.
abstract: BACKGROUND
  The elective treatment for noninvasive breast carcinoma has not yet been established. As a result of mammographic screening programs, the incidence of noninvasive tumors has increased and has lead to the same controversy already present had with invasive carcinomas: mastectomy or conserving therapy.
  
  
  METHODS
  Since 1990, 101 patients with noninvasive breast cancer were treated with irradiation following breast-conserving surgery. All the patients had irradiation of the whole breast (mean dose, 47.6 +/- 1.2 Gy). The radiation dose boost to the tumor bed was delivered in 28.7% of the cases (mean dose, 21.03 +/- 3.06 Gy), and in 71.3%, the boost was not administered.
  
  
  RESULTS
  With a median follow-up of 34 months, survival is 100%. The disease-free survival at 5 years by the Kaplan-Meier method is 93.6 +/- 8.65.
  
  
  CONCLUSIONS
  The conserving treatment is a valid option for treatment of patients with ductal carcinoma in situ.
authors.affiliation: Institut d'Oncologia Radioterápica, Hospital de l'Esperança, IMAS, Barcelona, Spain. nrodriguez@imas.imim.es
authors.forename: Nuria
authors.initials: N
authors.lastname: Rodríguez
authors.forename: Xavier
authors.initials: X
authors.lastname: Sanz
authors.forename: Manuel
authors.initials: M
authors.lastname: Algara
authors.forename: Palmira
authors.initials: P
authors.lastname: Foro
authors.forename: Carmen
authors.initials: C
authors.lastname: Auñón
authors.forename: Idoia
authors.initials: I
authors.lastname: Morilla
authors.forename: Anna
authors.initials: A
authors.lastname: Reig
authors.forename: Ferran
authors.initials: F
authors.lastname: Ferrer
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D005260:Female; D006801:Humans; D015412:Mastectomy, Segmental; D008875:Middle Aged; D011446:Prospective Studies; D018714:Radiotherapy, Adjuvant; D016019:Survival Analysis; D016896:Treatment Outcome