Accessory renal arteries are not related to hypertension risk: a review of MR angiography data.
OBJECTIVE
It has been hypothesized that accessory renal arteries are related to the risk of hypertension. Our goal was to determine the prevalence of accessory renal arteries in hypertensive patients using MR angiography and to assess the relationship between accessory renal arteries and hypertension risk.


METHODS
From 1996 to 2002, 185 hypertensive patients underwent MR angiography of the renal arteries at our institution for assessment of renal artery stenosis. MR angiograms were obtained using a 1.5-T magnet, IV gadolinium, and 3D gradient-echo sequences. Interpretations of the MR angiograms were retrospectively reviewed.


RESULTS
Of 185 hypertensive patients, 45 (24%) showed accessory renal arteries. Of these 45 patients, nine (20%) showed renal artery stenosis and 36 (80%) showed no significant stenosis. Of the 140 patients with a single renal artery, 42 (30%) showed renal artery stenosis and 98 (70%) showed no stenosis. The odds ratio of renal artery stenosis in the accessory renal artery group versus the single renal artery group was 0.58 (95% confidence interval, 0.26-1.3%), which is not statistically significant at a power of 0.85 (chi(2) = 1.705; p = 1.0).


CONCLUSIONS
We found no statistically significant difference in the prevalence of renal artery stenosis between patients with accessory renal arteries and those without accessory renal arteries. Assuming that the presence of two separate causes of hypertension in the same patient would be unlikely, this finding implies that accessory renal arteries are a vascular anomaly and not a direct cause of hypertension. The findings are potentially relevant in refuting the theory of accessory renal arteries as an anatomically treatable cause of hypertension.
Gupta
Avneesh
A
Department of Radiology, Boston University Medical Center, 88 E Newton Street, Boston, MA 02118, USA. avgupta@bmc.org
Tello
Richard
R
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D012077:Renal Artery / Q000002:abnormalities*; D012189:Retrospective Studies; D012307:Risk Factors