title: EPR and electronic spectral studies on Co(II), Ni(II) and Cu(II) complexes with a new tetradentate [N4] macrocyclic ligand and their biological activity.
abstract: Cobalt(II), nickel(II) and copper(II) complexes having the general composition M(L)X2 (where M = CO(II), Ni(II) and Cu(II), L = ligand, i.e. 3,4,12,13-tetraketo-2,5,11,14,19,20-hexaazatricyclo[13.3.1.1(6-10)]cosane; 1(19),6,8,10(20),15,17-hexaene and X stands for Cl-; NO3- and SO42-), have been prepared. The structure of the complexes has been elucidated by elemental analysis, molar conductance, magnetic susceptibility measurements, mass, IR, electronic and EPR spectral studies. The magnetic moment measurements of the complexes indicate that the metal ion is in high-spin state. On the basis of IR, electronic and EPR spectral studies an octahedral geometry was assigned for Co(II) and Ni(II) complexes whereas tetragonal geometry for Cu(II) complexes. This ligand and its complexes were also screened against bacteria and pathogenic fungi in vitro.
authors.affiliation: Department of Chemistry, Zakir Husain College, University of Delhi, JLN-Marg, New Delhi 110 002, India. schandra_00@yahoo.com
authors.forename: Sulekh
authors.initials: S
authors.lastname: Chandra
authors.forename: Lokesh Kumar
authors.initials: LK
authors.lastname: Gupta
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology; D003035:Cobalt / Q000737:chemistry; D003300:Copper / Q000737:chemistry; D004563:Electrochemistry; D004578:Electron Spin Resonance Spectroscopy; D008024:Ligands; D047028:Macrocyclic Compounds / Q000737:chemistry* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D008280:Magnetics; D008826:Microbial Sensitivity Tests; D009532:Nickel / Q000737:chemistry; D046590:Spectroscopy, Electron Energy-Loss; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D008024:Ligands; D047028:Macrocyclic Compounds; D003035:Cobalt; D003300:Copper; D009532:Nickel