[Correlation study between the connexin43 and the myocardial ischemia in rabbit].
OBJECTIVE
To study the correlation between quantity of the connexin43 express and ischemia time in rabbit.


METHODS
Left coronary arteries were ligated to create early myocardial ischemia during distinct time, HBFP staining was used in the ischemia spot and SP method was used to show the expression of connexin43 and the ischemia are were measured by the computer image analysis.


RESULTS
Negative correlation was observed between the connexin43 quantity and the ischemia time. The significant was difference.


CONCLUSIONS
With ischemia time raised, expression of connexin43 was descented.
Chen
Yang
Y
West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China. chy5454@163.com
Hu
Huazi
H
Liao
Zhigang
Z
D000818:Animals; D018031:Connexin 43 / Q000378:metabolism*; D005260:Female; D007150:Immunohistochemistry; D008297:Male; D017202:Myocardial Ischemia / Q000378:metabolism* / Q000473:pathology; D009206:Myocardium / Q000378:metabolism / Q000473:pathology; D011817:Rabbits; D013194:Staining and Labeling / Q000379:methods; D013997:Time Factors
D018031:Connexin 43