title: Magnetic resonance image-reversible findings in a patient with general paresis.
abstract: METHODS
  We describe clinical, cerebrospinal fluid (CSF), and magnetic resonance imaging (MRI) findings in a patient with general paresis. MRI demonstrated cortical-subcortical atrophy and broad-coalescent high-intensity T2 lesions in right frontotemporal lobes.
  
  
  RESULTS
  After intravenous penicillin therapy, the size of these lesions diminished dramatically. That regression correlated with improvement in neuropsychologic test and CSF analysis.
  
  
  CONCLUSIONS
  To our knowledge, this is the first case reported in the literature of MRI-reversible lesions in a patient with general paresis. We suggest that MRI is of prognostic value in patients with general paresis. Severe atrophy, especially in the temporal lobe, could be a marker of bad clinical outcome.
authors.affiliation: Department of Neurology, Hospital Mancha Centro, Alcazar de San Juan (Ciudad Real), Spain. aberbel@yahoo.com
authors.forename: Angel
authors.initials: A
authors.lastname: Berbel-Garcia
authors.forename: Jesus
authors.initials: J
authors.lastname: Porta-Etessam
authors.forename: Antonio
authors.initials: A
authors.lastname: Martinez-Salio
authors.forename: Jose Maria
authors.initials: JM
authors.lastname: Millan-Juncos
authors.forename: David A
authors.initials: DA
authors.lastname: Perez-Martinez
authors.forename: Rosana A
authors.initials: RA
authors.lastname: Saiz-Diaz
authors.forename: Maria
authors.initials: M
authors.lastname: Toledo-Heras
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009494:Neurosyphilis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D010406:Penicillins / Q000627:therapeutic use
chemical_list: D010406:Penicillins