Optical microrheology using rotating laser-trapped particles.
We demonstrate an optical system that can apply and accurately measure the torque exerted by the trapping beam on a rotating birefringent probe particle. This allows the viscosity and surface effects within liquid media to be measured quantitatively on a micron-size scale using a trapped rotating spherical probe particle. We use the system to measure the viscosity inside a prototype cellular structure.
Bishop
Alexis I
AI
Centre for Biophotonics and Laser Science, Department of Physics, The University of Queensland, Brisbane QLD 4072, Australia. A.I.Bishop@hw.ac.uk
Nieminen
Timo A
TA
Heckenberg
Norman R
NR
Rubinsztein-Dunlop
Halina
H
D002119:Calcium Carbonate / Q000737:chemistry; D004058:Diffusion; D055095:Optics and Photonics; D012212:Rheology / Q000379:methods*; D019415:Torque; D014783:Viscosity; D014867:Water / Q000737:chemistry
D014867:Water; D002119:Calcium Carbonate