Identifying specific conformations by using a carbohydrate scaffold: discovery of subtype-selective LPA-receptor agonists and an antagonist.
Tamaruya
Yoko
Y
Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-Ku, Tokyo 113-0033, Japan.
Suzuki
Masato
M
Kamura
Goshu
G
Kanai
Motomu
M
Hama
Kotaro
K
Shimizu
Kumiko
K
Aoki
Junken
J
Arai
Hiroyuki
H
Shibasaki
Masakatsu
M
D002236:Carbohydrate Conformation; D002241:Carbohydrates / Q000737:chemistry*; D015195:Drug Design; D007202:Indicators and Reagents; D043562:Receptors, G-Protein-Coupled / Q000819:agonists* / Q000037:antagonists & inhibitors* / Q000737:chemistry; D049368:Receptors, Lysophosphatidic Acid
D002241:Carbohydrates; D007202:Indicators and Reagents; D043562:Receptors, G-Protein-Coupled; D049368:Receptors, Lysophosphatidic Acid