title: The contribution of farm animals to human health.
abstract: Farm animals and their products have a longstanding and successful history of providing significant contributions to human nutrition, clothing, facilitation of labour, research, development and medicine and have thus been essential in improving life expectancy and human health. With the advent of transgenic technologies the potential of farm animals for improving human health is growing and many areas remain to be explored. Recent breakthroughs in reproductive technologies, such as somatic cloning and in vitro embryo production, and their merger with molecular genetic tools, will further advance progress in this field. Here, we have summarized the contribution of farm animals to human health, covering the production of antimicrobial peptides, dietary supplements or functional foods, animals used as disease models and the contribution of animals to solving urgent environmental problems and challenges in medicine such as the shortage of human cells, tissues and organs and therapeutic proteins. Some of these areas have already reached the level of preclinical testing or commercial application, others will be further advanced only when the genomes of the animals concerned have been sequenced and annotated. Provided the necessary precautions are being taken, the transmission of pathogens from animals to humans can be avoided to provide adequate security. Overall, the promising perspectives of farm animals and their products warrant further research and development in this field.
authors.affiliation: Department of Biotechnology, Institut für Tierzucht, Mariensee, D-31535 Neustadt, Germany.
authors.forename: Wilfried A
authors.initials: WA
authors.lastname: Kues
authors.forename: Heiner
authors.initials: H
authors.lastname: Niemann
mesh_terms: D000825:Animal Structures / Q000637:transplantation; D000818:Animals; D000829:Animals, Domestic; D030801:Animals, Genetically Modified; D023181:Antimicrobial Cationic Peptides / Q000096:biosynthesis / Q000235:genetics; D017690:Cell Transplantation; D019976:Cloning, Organism / Q000379:methods / Q000706:statistics & numerical data; D003611:Dairy Products; D004195:Disease Models, Animal; D004787:Environmental Pollution / Q000517:prevention & control; D005260:Female; D030841:Food, Genetically Modified; D006262:Health; D006801:Humans; D008321:Mammary Glands, Animal / Q000378:metabolism; D008461:Meat Products; D008511:Medicine; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000627:therapeutic use; D016378:Tissue Transplantation; D014183:Transplantation, Heterologous
chemical_list: D023181:Antimicrobial Cationic Peptides; D011994:Recombinant Proteins