title: A comparison between single- and double-breath vital capacity inhalation induction with 8% sevoflurane in children.
abstract: BACKGROUND
  This study was conducted to determine if a double-breath (DB) vital capacity (VC) rapid inhalation induction using immediate high-inspired concentration of sevoflurane is as well tolerated as a single-breath (SB) technique and if it results in a shorter induction time.
  
  
  METHODS
  A total of 104 children, ASA I-II, 6 year and above, undergoing elective surgery were randomly assigned to two groups: SB VC inhalation induction or DB VC inhalation induction with 8% sevoflurane in 66% nitrous oxide. The induction time, complications (cough, laryngospasm, breath-hold, movement, salivation) and level of satisfaction were documented.
  
  
  RESULTS
  Induction was significantly faster in the DB group (41 +/- 9 s) compared with the SB group (50 +/- 14 s). DB inhalation induction was associated with fewer complications (15.4%) than the SB technique (50%).
  
  
  CONCLUSIONS
  Double-breath VC inhalation induction with 8% sevoflurane is as well tolerated as a SB technique and results in a faster onset of anaesthesia.
authors.affiliation: Department of Anaesthesia (Paediatrics), KK Women's and Children's Hospital, Singapore. hokokyuen@yahoo.com.sg
authors.forename: Kok-Yuen
authors.initials: KY
authors.lastname: Ho
authors.forename: Wee-Leng
authors.initials: WL
authors.lastname: Chua
authors.forename: Serene S T
authors.initials: SS
authors.lastname: Lim
authors.forename: Agnes S B
authors.initials: AS
authors.lastname: Ng
mesh_terms: D000762:Anesthesia Recovery Period; D000769:Anesthesia, Inhalation / Q000009:adverse effects / Q000379:methods*; D018685:Anesthetics, Inhalation; D002648:Child; D005260:Female; D006801:Humans; D001239:Inhalation; D008297:Male; D008738:Methyl Ethers; D009609:Nitrous Oxide; D017060:Patient Satisfaction; D000077149:Sevoflurane; D013997:Time Factors; D014797:Vital Capacity
chemical_list: D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane; D009609:Nitrous Oxide