title: Electron microscopic cytochemistry of adenylyl cyclase activity in mouse spermatozoa.
abstract: We investigated adenylyl cyclase activity of mouse spermatozoa by electron microscopic cytochemistry. Subcellular localization of enzyme activity was determined in the presence and absence of bicarbonate ions. Results confirm the existence in sperm of a bicarbonate-regulated adenylyl cyclase, which suggests microdomain signaling.
authors.affiliation: Dipartimento di Scienze Biochimiche Biotecnologie Molecolari, Sezione Biochimica Cellulare, Università di Perugia, Perugia, Italia.
authors.forename: Lavinia
authors.initials: L
authors.lastname: Liguori
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Rambotti
authors.forename: Ilaria
authors.initials: I
authors.lastname: Bellezza
authors.forename: Alba
authors.initials: A
authors.lastname: Minelli
mesh_terms: D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D008297:Male; D051379:Mice; D008854:Microscopy, Electron; D013094:Spermatozoa / Q000201:enzymology* / Q000648:ultrastructure
chemical_list: D000262:Adenylyl Cyclases