Liver transplantation for treatment of metastatic neuroendocrine tumors.
Liver transplantation can be considered a therapeutic option for patients with neuroendocrine tumors only metastatic to the liver. Important selection criteria are well-differentiated tumors and a low proliferation rate (Ki67 <10%). In this series, orthopic liver transplantation offered good relief of symptoms and long disease-free intervals with initial survival of grafts and patients as in benign disease. The experience with multivisceral transplantation is still limited.
Ahlman
Håkan
H
Department of Surgery and Department of Pathology, Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden. hakan.ahlman@surgery.gu.se
Friman
Styrbjörn
S
Cahlin
Christian
C
Nilsson
Ola
O
Jansson
Svante
S
Wängberg
Bo
B
Olausson
Michael
M
D000328:Adult; D002276:Carcinoid Tumor / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007340:Insulinoma / Q000473:pathology; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D018358:Neuroendocrine Tumors / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D010190:Pancreatic Neoplasms / Q000473:pathology; D015996:Survival Rate