[The relationship between periodontal diseases and prostacyclin in saliva of periodontal patients by RIA]
The purpose of this investigation was to measure the changes of Prostacyclin(PG12) occuring in gingivitis and periodontitis.Fifteen cases of periodontitis,ten cases of gingivitis and ten cases of healthy participated in this study,Saliva was taken before treatment,Prostacyclin in saliva was measure by radioimmunoassay(RIA).The results showed that prostacyclin of human saliva is increased from healthy gingivitis to periodontitis.There is a statistical difference between groups,6-k-PGF1alpha in saliva of periodontitis is 3.6 folds of healthy.Gingivitis is 2.6 folds of healthy.There is also a significant difference between adult periodontitis our findings suggested that prostacyclin may play an important role in etiology of periodontal disease.Measured 6-k-PGF1alpha in saliva may indicate the severity of periodontal disease.
Chen
T L
TL
Department of Periodontology,Stomatological College, The Fourth Military Medical University.Xi'an 710032, China.
Zhou
Y J
YJ
Wu
Z F
ZF