title: Effect of fluvastatin therapy on coronary flow reserve in patients with hypercholesterolemia.
abstract: Coronary flow reserve was evaluated using transthoracic Doppler echocardiography before and after 3 months of fluvastatin therapy in patients with hypercholesterolemia. Coronary flow reserve increased significantly after lipid-lowering therapy, and coronary microcirculation was improved in patients with hypercholesterolemia.
authors.affiliation: Department of Internal Medicine and Cardiology, Osaka City University Medical School, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.
authors.forename: Kohei
authors.initials: K
authors.lastname: Fujimoto
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hozumi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Watanabe
authors.forename: Kenei
authors.initials: K
authors.lastname: Shimada
authors.forename: Masaaki
authors.initials: M
authors.lastname: Takeuchi
authors.forename: Yuji
authors.initials: Y
authors.lastname: Sakanoue
authors.forename: Naruhito
authors.initials: N
authors.lastname: Shimizu
authors.forename: Ryo
authors.initials: R
authors.lastname: Ostuka
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Kawase
authors.forename: Kazuo
authors.initials: K
authors.lastname: Sakamoto
authors.forename: Minoru
authors.initials: M
authors.lastname: Yoshiyama
authors.forename: Yuji
authors.initials: Y
authors.lastname: Baba
authors.forename: Kazuo
authors.initials: K
authors.lastname: Haze
authors.forename: Junichi
authors.initials: J
authors.lastname: Yoshikawa
mesh_terms: D003326:Coronary Circulation / Q000502:physiology*; D015150:Echocardiography, Doppler / Q000379:methods; D005229:Fatty Acids, Monounsaturated / Q000627:therapeutic use*; D005260:Female; D000077340:Fluvastatin; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D006937:Hypercholesterolemia / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D007211:Indoles / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D013997:Time Factors
chemical_list: D005229:Fatty Acids, Monounsaturated; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D007211:Indoles; D000077340:Fluvastatin