Transcription rate of RNA polymerase under rotary torque.
We investigated the transcription rates of RNA polymerases that were subjected to rotational drag. By combining chemical kinetics with mechanical equations, we derived formulas for the transcription rate in the case where the torque was caused by the hydrodynamic drag to DNA rotation.
Kiryu
H
H
Department of Information Science, NAIST, Nara, Japan. hisano-k@is.aist-nara.ac.jp
D003198:Computer Simulation; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D012321:DNA-Directed RNA Polymerases / Q000737:chemistry* / Q000378:metabolism; D008956:Models, Chemical; D008957:Models, Genetic; D020409:Molecular Motor Proteins / Q000737:chemistry* / Q000502:physiology; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry / Q000378:metabolism*; D012399:Rotation; D012680:Sensitivity and Specificity; D019415:Torque; D014158:Transcription, Genetic
D020409:Molecular Motor Proteins; D012313:RNA; D004247:DNA; D012321:DNA-Directed RNA Polymerases