title: Biological activity of phenolic compounds from Alchornea glandulosa.
abstract: From the isopropyl acetate fraction obtained by partition of the leaves ethanolic extract of Alchornea glandulosa, six phenolic compounds were isolated and identified. General lethality of the extract, fractions and compounds were assayed with Brine Shrimp Test (BST) and with Antifeedant Activity Bioassay (AAB) against neonate larvae of Spodoptera frugiperda. Aqueous fraction and ethyl gallate, one of the major constituents of the polar fraction, have shown the highest toxicity in BST. Ethanolic extract, isopropyl acetate fraction and gallic acid reduced significantly larval growth of S. frugiperda neonates.
authors.affiliation: Departamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, A.A. 27586, Bogotá DC 1, Colombia.
authors.forename: A
authors.initials: A
authors.lastname: Urrea-Bulla
authors.forename: M
authors.initials: M
authors.lastname: Suárez M
authors.forename: B
authors.initials: B
authors.lastname: Moreno-Murillo
mesh_terms: D000818:Animals; D001156:Artemia / Q000187:drug effects; D019665:Euphorbiaceae; D005247:Feeding Behavior / Q000187:drug effects*; D007306:Insecticides / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D010636:Phenols / Q000494:pharmacology*; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves; D018411:Spodoptera / Q000187:drug effects
chemical_list: D007306:Insecticides; D010636:Phenols; D010936:Plant Extracts