Change in bispectral index during epileptiform electrical activity under sevoflurane anesthesia in a patient with epilepsy.
We observed abnormal fluctuation in Bispectral Index (BIS) caused by repeated alternations between two electroencephalographic (EEG) waveform patterns in a patient with a recent history of epileptic seizure under sevoflurane anesthesia. The repetitive development of the abnormal EEG changes (slow delta with or without spike) and the fluctuation in BIS disappeared almost immediately after administration of anticonvulsants. BIS may give useful information not only on the sedative-hypnotic state, but also on the development of and recovery from abnormal epileptiform EEG activity.


CONCLUSIONS
During epileptiform electroencephalographic activity (EEG), the Bispectral Index shows an abnormal fluctuation caused by repeated abrupt alterations between normal EEG and abnormal epileptiform EEG patterns.
Chinzei
Mieko
M
*Surgical Centre, Graduate School of Medicine, and †Department of Anesthesiology and Pain Relief Center, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Sawamura
Shigehito
S
Hayashida
Masakazu
M
Kitamura
Takayuki
T
Tamai
Hisayoshi
H
Hanaoka
Kazuo
K
D018685:Anesthetics, Inhalation / Q000494:pharmacology* / Q000627:therapeutic use; D004569:Electroencephalography / Q000187:drug effects* / Q000379:methods; D004827:Epilepsy / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008738:Methyl Ethers / Q000494:pharmacology* / Q000627:therapeutic use; D008875:Middle Aged; D000077149:Sevoflurane
D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane