title: [Effect of arthropod extracts on the multiplication of Toxoplasma gondii in mouse peritoneal macrophages].
abstract: Treatment of toxoplasmosis usually causes secondary effects. It is important to find active substances extracted from natural organisms. In this work we studied some arthropod extracts that have effect against Toxoplasma multiplication inside mouse macrophages. After studying 382 extracts, 23 were selected on the basis of the activity and we found that 13 extracts from orders Polydesmida, Lepidoptera, Orthoptera and Hymenoptera exerted an important inhibition of Toxoplasma multiplication.
authors.affiliation: Centro de Investigación en Enfermedades Tropicales, Departamento de Parasitología, Facultad de Microbiología, Universidad de Costa Rica, 2060, Costa Rica.
authors.forename: Misael
authors.initials: M
authors.lastname: Chinchilla Carmona
authors.forename: Marlen
authors.initials: M
authors.lastname: Herrera Corrales
authors.forename: Olga Marta
authors.initials: OM
authors.lastname: Guerrero Bermúdez
authors.forename: Alberto
authors.initials: A
authors.lastname: Jiménez Somarribas
authors.forename: Guiselle
authors.initials: G
authors.lastname: Tamayo
authors.forename: Ana
authors.initials: A
authors.lastname: Sittenfeld Appel
authors.forename: Vanessa
authors.initials: V
authors.lastname: Nielsen
authors.forename: Priscila
authors.initials: P
authors.lastname: Hurtado
mesh_terms: D000818:Animals; D001181:Arthropods / Q000737:chemistry* / Q000145:classification; D017737:Macrophages, Peritoneal / Q000469:parasitology*; D051379:Mice; D013997:Time Factors; D014020:Tissue Extracts / Q000494:pharmacology*; D014122:Toxoplasma / Q000187:drug effects*
chemical_list: D014020:Tissue Extracts