Amyloid tumor in the anterior mediastinum: report of a case.
A 33-year-old woman being treated for rheumatoid arthritis was referred to our hospital for investigation of a mediastinal mass. A chest computed tomography scan showed an anterior mediastinal mass, 8.5 x 7.0 cm in size, with a cystic lesion and calcification. These findings were suggestive of either a noninvasive thymoma or a mature teratoma. Therefore, we performed tumor resection and thymectomy. Histologically, the tumor consisted of diffuse deposits of massive eosinophilic amorphous material. The tumor was stained red-orange by Congo red, and the staining disappeared following potassium permanganate digestion. Based on these findings, a diagnosis of reactive amyloidosis of the amyloid A-protein-derived type was made. Amyloidosis in the mediastinum has rarely been described.
Takamori
Shinzo
S
Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan.
Yano
Hirohisa
H
Hayashi
Akihiro
A
Fukunaga
Mari
M
Miwa
Keisuke
K
Maeshiro
Kanetaka
K
Shirouzu
Kazuo
K
D000328:Adult; D000686:Amyloidosis / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D001172:Arthritis, Rheumatoid; D005260:Female; D006801:Humans; D008477:Mediastinal Diseases / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D013950:Thymus Gland / Q000473:pathology