title: Psychosocial stress and cardiovascular disease: how to heal a broken heart.
abstract: Psychosocial stress induces adverse changes in autonomic tone accounting for substantial but modifiable cardiovascular risk. Various factors, including depression, social isolation, hostility and anxiety increase cardiovascular risk, whereas social support, altruism, faith and optimism reduce risk.
authors.affiliation: Mid America Heart Institute, Cardiovascular Consultants, Kansas City, Mo., USA.
authors.forename: James H
authors.initials: JH
authors.lastname: O'Keefe
authors.forename: Walker S
authors.initials: WS
authors.lastname: Poston
authors.forename: C Keith
authors.initials: CK
authors.lastname: Haddock
authors.forename: Richard M
authors.initials: RM
authors.lastname: Moe
authors.forename: William
authors.initials: W
authors.lastname: Harris
mesh_terms: D001341:Autonomic Nervous System / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000503:physiopathology / Q000517:prevention & control* / Q000523:psychology*; D002908:Chronic Disease; D006801:Humans; D008016:Life Change Events; D012068:Religion and Medicine; D012944:Social Support; D013315:Stress, Psychological / Q000150:complications* / Q000503:physiopathology / Q000517:prevention & control