Vesicular glutamate transporter immunoreactivity in the central and peripheral endings of muscle-spindle afferents.
Expression of vesicular glutamate transporters (VGLUTs: VGLUT1, VGLUT2 and VGLUT3) in muscle spindle afferents was examined in rats. VGLUT1 immunoreactivity was detected in the sensory endings on the equatorial and juxta-equatarial regions of intrafusal fibers as well as in many axon terminals within lamina IX of the spinal cord. VGLUT1 might be expressed not only in the central axon terminals but also in the peripheral sensory endings of muscle-spindle afferents.
Wu
Sheng-Xi
SX
Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.
Koshimizu
Yoshinori
Y
Feng
Yu-Peng
YP
Okamoto
Keiko
K
Fujiyama
Fumino
F
Hioki
Hiroyuki
H
Li
Yun-Qing
YQ
Kaneko
Takeshi
T
Mizuno
Noboru
N
D000344:Afferent Pathways / Q000378:metabolism* / Q000648:ultrastructure; D026922:Amino Acid Transport Systems, Acidic / Q000378:metabolism*; D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism*; D002795:Choline O-Acetyltransferase / Q000378:metabolism; D007839:Functional Laterality; D007150:Immunohistochemistry; D008297:Male; D026901:Membrane Transport Proteins; D016253:Microscopy, Immunoelectron / Q000379:methods; D009470:Muscle Spindles / Q000378:metabolism* / Q000648:ultrastructure; D051381:Rats; D017208:Rats, Wistar; D013569:Synapses / Q000378:metabolism / Q000648:ultrastructure; D050598:Vesicular Glutamate Transport Protein 1; D050599:Vesicular Glutamate Transport Protein 2; D050496:Vesicular Glutamate Transport Proteins; D033921:Vesicular Transport Proteins
D026922:Amino Acid Transport Systems, Acidic; D002352:Carrier Proteins; D026901:Membrane Transport Proteins; C493475:Slc17a6 protein, rat; C493466:Slc17a7 protein, rat; C482103:Slc17a8 protein, rat; D050598:Vesicular Glutamate Transport Protein 1; D050599:Vesicular Glutamate Transport Protein 2; D050496:Vesicular Glutamate Transport Proteins; D033921:Vesicular Transport Proteins; D002795:Choline O-Acetyltransferase