A blue-to-red energy-transfer thymidine analogue that functions in DNA.
The thymidine analogue 1 is a blue-to-red energy transfer cassette designed to absorb UV light in the 300 nm region and emit it as fluorescence at around 520 nm. When incorporated into DNA, the fluorescence intensity of this modified nucleobase is not significantly reduced by the surrounding structure in the oligonucleotides. [structure--see text]
Jiao
Guan-Sheng
GS
Department of Chemistry, Texas A & M University, Box 30012, College Station, TX 77842-3012, USA.
Kim
Taeg Gyum
TG
Topp
Michael R
MR
Burgess
Kevin
K
D001483:Base Sequence; D004247:DNA / Q000737:chemistry* / Q000235:genetics; D004735:Energy Transfer; D015394:Molecular Structure; D009838:Oligodeoxyribonucleotides / Q000737:chemistry / Q000235:genetics; D013050:Spectrometry, Fluorescence; D013936:Thymidine / Q000031:analogs & derivatives* / Q000737:chemistry*
D009838:Oligodeoxyribonucleotides; D004247:DNA; D013936:Thymidine