"Mu rhythm status" and clinical correlates.
Rolandic mu rhythm is usually limited to brief stretches of 0.5 to 2 sec duration. Two observations of status-like enhancement of mu rhythm have prompted this report. In both cases, 4-hour EEG-Video-Monitoring was used. Clinically, the reported cases differed considerably. Case 1 showed nearly continuous mu activity associated with general motionlessness: akinesia/amimia but without rigidity, caused by frontal lobe impairment due to multiple sclerosis. In Case 2, an impressive mu-status started in drowsiness and was presumably attributable to levitiracetam (which had rendered seizure-free the patient's formerly severe case of temporal lobe epilepsy). Mu rhythm status, thus far, is an unknown EEG entity. It can be caused by impaired fronto-motor input and may also constitute a medication-effect (levitiracetam).
Niedermeyer
E
E
Division of Neurology, Department of Internal Medicine, The Sinai Hospital, Baltimore, Maryland, USA.
Goldszmidt
Adrian
A
Ryan
Dawn
D
D003937:Diagnosis, Differential; D004569:Electroencephalography / Q000187:drug effects* / Q000379:methods*; D019305:Epilepsy, Rolandic / Q000175:diagnosis* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D000077287:Levetiracetam; D008875:Middle Aged; D009044:Motor Cortex / Q000187:drug effects* / Q000503:physiopathology*; D010889:Piracetam / Q000008:administration & dosage* / Q000009:adverse effects* / Q000031:analogs & derivatives; D013223:Statistics as Topic
D000077287:Levetiracetam; D010889:Piracetam