title: Epidemiology and characterization of Bordetella parapertussis strains isolated between 1995 and 2002 in and around Warsaw, Poland.
abstract: The aim of the study presented here was to analyze parapertussis infections occurring in the region of Warsaw, Poland, between 1995 and 2002 and to characterize the Bordetella parapertussis isolates using macrorestriction digestion of genomic DNA. Fourteen of the 17 patients with confirmed Bordetella parapertussis infection were between the ages of 5 and 9 years, and 14 had documented vaccination with the diphtheria-tetanus-pertussis whole-cell vaccine; for the remaining three patients vaccination data was not available. DNA fingerprinting performed using recommended standard methodology revealed a close relationship between the examined strains and reference strain ATCC 9305, thus confirming the conservative nature of Bordetella parapertussis.
authors.affiliation: Center of Microbiology and Infectious Diseases, National Institute of Public Health, Chelmska Street 30/34, 00-725 Warsaw, Poland. iletowska@cls.edu.pl
authors.forename: I
authors.initials: I
authors.lastname: Letowska
authors.forename: W
authors.initials: W
authors.lastname: Hryniewicz
mesh_terms: D017677:Age Distribution; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001885:Bordetella Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D042483:Bordetella parapertussis / Q000302:isolation & purification*; D002648:Child; D002675:Child, Preschool; D004269:DNA, Bacterial / Q000032:analysis; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D011044:Poland / Q000453:epidemiology; D012150:Polymorphism, Restriction Fragment Length; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D014505:Urban Population
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial