Biological activity of 2-hydroxythiobenzanilides and related compounds.
Thiobenzanilides substituted in thioacyl moiety with one or more hydroxy groups are interesting for their biological effects depending on the substitution pattern. New findings in mechanisms of action of 2-hydroxybenzanilides insert 2-hydroxybenzanilides and their analogues, e.g. substituted thiobenzanilides, among interesting compounds in the development of new potential antimicrobial drugs. The present review paper with 32 references links up with our previous communications which reviewed biological activity of 2-hydroxybenzanilides and related compounds, and includes the research of mono-, di-, and trihydroxythiobenzanilides carried out in the last period.
Kubicová
L
L
Department of Inorganic and Organic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Prague, Czech Republic. kubicova@faf.cuni.cz
Sustr
M
M
Pravda
M
M
Waisser
K
K
D000813:Anilides / Q000737:chemistry / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D002626:Chemistry, Pharmaceutical; D009161:Mycobacterium / Q000187:drug effects*; D013329:Structure-Activity Relationship
D000813:Anilides; D000900:Anti-Bacterial Agents; C034595:benzanilide