title: Multimodal functional mapping of sensorimotor cortex prior to resection of an epileptogenic perirolandic lesion.
abstract: The effects of chronic epileptogenic lesions on functional anatomy are under debate. Our recent experience during mapping and resection of a lesion in sensorimotor cortex supports the idea that epileptogenic lesions may prompt development of alternate cortical motor representations. Multimodal mapping may uncover alternate areas of functionality that make surgery feasible even when conventional neuroanatomy suggests otherwise. Newer methods such as electrocorticographic spectral analysis may complement traditional electrical cortical stimulation mapping.
authors.affiliation: Department of Neurology, University of California San Francisco School of Medicine, San Francisco, CA, USA. heidi@itsa.ucsf.edu
authors.forename: Heidi E
authors.initials: HE
authors.lastname: Kirsch
authors.forename: Jehuda P
authors.initials: JP
authors.lastname: Sepkuty
authors.forename: Nathan E
authors.initials: NE
authors.lastname: Crone
mesh_terms: D000293:Adolescent; D001931:Brain Mapping; D003952:Diagnostic Imaging; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000379:methods; D004827:Epilepsy / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D005073:Evoked Potentials, Somatosensory / Q000502:physiology / Q000528:radiation effects; D006801:Humans; D008297:Male; D009044:Motor Cortex / Q000473:pathology / Q000503:physiopathology*; D013003:Somatosensory Cortex / Q000473:pathology / Q000503:physiopathology*