title: Topical anaesthetic use for treating premature ejaculation: a double-blind, randomized, placebo-controlled study.
abstract: OBJECTIVE
  To assess the use of a topical anaesthetic mixture to improve premature ejaculation (PE), for which penile hypersensitivity might be a cause.
  
  
  METHODS
  The study included 42 men divided in two groups; group A used a lidocaine-prilocaine solution and group B used an inert cream. The tubes of cream were distributed randomly and participants asked to note any unpleasant symptoms, difficulties and the results of each attempt at intercourse, assessed by the intravaginal ejaculatory latency time (IELT).
  
  
  RESULTS
  There was a significant increase in the mean (sd) IELT, from 1.49 (0.9) to 8.45 (0.9) min (P < 0.001) in group A but not in group B, at 1.67 (0.7) to 1.95 (0.12) min (P > 0.05).
  
  
  CONCLUSIONS
  We suggest that anaesthetic cream might be effective for treating PE.
authors.affiliation: Urology Surgery Service, Marieta Konder Bornhausen Hospital, Itajaí, Brazil. wbusato@melim.com.br
authors.forename: W
authors.initials: W
authors.lastname: Busato
authors.forename: C C
authors.initials: CC
authors.lastname: Galindo
mesh_terms: D000287:Administration, Topical; D000328:Adult; D019162:Anesthetics, Combined / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D004311:Double-Blind Method; D004542:Ejaculation / Q000187:drug effects*; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D011318:Prilocaine / Q000008:administration & dosage*; D012735:Sexual Dysfunction, Physiological / Q000188:drug therapy*
chemical_list: D019162:Anesthetics, Combined; D000779:Anesthetics, Local; D011318:Prilocaine; D008012:Lidocaine