[Experience on transplantation of auto-pulmonary graft treating with congenital aortic disease].
OBJECTIVE
To summarize the experience on auto-pulmonary transplantation (Ross procedure) treating with congenital aortic disease.


METHODS
From October 1994 to November 2003, 20 cases of Ross procedure were performed to treat with congenital aortic disease, Male: 15 cases; Female: 5 cases; age: 25 years;


METHODS
congenital heart disease (CHD), aortic abnormalities: 12 cases; aortic valve prolapse: 5 cases; aortic valve hypogenesis: 3 cases; combined with subacute bacterial endocarditis (SBE): 4 cases, and ventricle septal defect (VSD): 2 cases; UCG showed aortic stenosis(AS) and/or aortic insufficience (AI) (moderate to severe), Left ventricle diastole diameter (LVDD): (60.51 +/- 11.87) mm, the grade pressure across aortic valve: (27.04 +/- 6.80) mmHg, heart function (NYHA): Class II: 13 cases; Class III: 3 cases; all cases were performed under CPB and moderate hypothermia, the operation procedure was following: (1) taking off auto-pulmonary artery valve; (2) removing dysfunctional aortic valve and auto-transplantation of pulmonary valve on aortic root; (3) putting a pulmonary homograft to rebuild right ventricular outflow tract.


RESULTS
The mortality was 0 during stay at hospital, aortic valve function were all normal, LVDD decreased significantly (t = 3.4007, P = 0.0008), the grade pressure across aortic valve was in normal limitation, (6.8 +/- 0.19) mmHg. Follow-up showed heart function was in Class I (NYHA), aortic and pulmonary valve function was very well.


CONCLUSIONS
Ross procedure is a kind of effective alterative operation for treating with congenital aortic valve disease, with good short and middle term results.
Li
Wen-bin
WB
Department I of Cardiovascular, Institute of Heart, Lung and Blood Vessel, Anzhen Hospital, Capital University of Medical Science, Beijing 100029, China.
Zhang
Jian-qun
JQ
Zhou
Hai-bo
HB
Wang
Sheng-xun
SX
Liu
Wei
W
Bo
Ping
P
Gan
Hui-li
HL
Mao
Bin
B
D000293:Adolescent; D000328:Adult; D001022:Aortic Valve Insufficiency / Q000601:surgery*; D001023:Aortic Valve Prolapse / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011664:Pulmonary Valve / Q000637:transplantation*; D014182:Transplantation, Autologous