[Experimental study of antioxidant properties of a new dry extract (Nephrophyt) obtained on the basis of therapeutic vegetable raw material].
The antioxidant properties of a new Russian vegetable preparation (Nephrophyt), known for its nephroprotective effect, were investigated experimentally in vivo and in vitro in modeled systems applicable to evaluating the capture of super-radicals on the basis of nitro-blue tetrazole (NBT). The preparation was demonstrated to oppress effectively the formation of the primary peroxidation products, i.e. diene conjugates, in rats in no way affected the synthesis of the peroxidation secondary products, i.e. malonic dialdehyde. The found effect correlates with a pronounced ability of the preparation to act as a "capturer" of 02-radical in vitro. Besides, the outlooks for using Nephrophyt as an antioxidant and as a tool for investigating the peroxidation reactions are under consideration.
Markarian
A A
AA
Aliautdin
R N
RN
Dargaeva
T D
TD
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D013053:Spectrophotometry; D013481:Superoxides / Q000037:antagonists & inhibitors
D000975:Antioxidants; D010936:Plant Extracts; D013481:Superoxides