title: A study of serum malondialdehyde and interleukin-6 levels in young women with dysmenorrhea in Taiwan.
abstract: The purpose of this study was to examine whether the symptoms of dysmenorrhea in young women were related to serum malondialdehyde (MDA) and interleukin-6 (IL-6) levels. Ninety-four non-smoking and non-drinking female subjects without serious disease from a nursing college in Taiwan were divided into two groups. Group 1 consisted of 51 subjects without dysmenorrheal, and Group 2 of 43 subjects with dysmenorrheal symptom. All subjects were provided informed consent. Results showed that the serum levels of MDA and of IL-6 were significantly different between the two groups (P < 0.05) and (P < 0.005), respectively. We conclude that the pathological mechanism of dysmenorrhea is mediated by oxidative stress caused by the action of cytokine.
authors.affiliation: National Taipei College of Nursing, No. 365, Ming-Te Road, Peitou 112, Taipei, Taiwan.
authors.forename: Mei-Ling
authors.initials: ML
authors.lastname: Yeh
authors.forename: Hsing-Hsia
authors.initials: HH
authors.lastname: Chen
authors.forename: Edmund C
authors.initials: EC
authors.lastname: So
authors.forename: Chi-Feng
authors.initials: CF
authors.lastname: Liu
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood*; D004412:Dysmenorrhea / Q000097:blood*; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D008315:Malondialdehyde / Q000097:blood*; D018384:Oxidative Stress / Q000502:physiology; D013624:Taiwan
chemical_list: D015415:Biomarkers; D015850:Interleukin-6; D008315:Malondialdehyde