The role of radionuclide bone scintigraphy in fibrous dysplasia of bone.
OBJECTIVE
The purpose of this study was to study the characteristics of fibrous dysplasia (FD) of bone on bone scans and to evaluate the diagnostic value of radionuclide bone scans in FD.


METHODS
Radionuclide bone scans were performed in 42 cases of histopathologically proven FD and the results were compared with other imaging modalities. A retrospective study method was used to analyze the imaging results.


RESULTS
Although FD showed nonspecific increased 99m-Tc MDP uptake, its appearance is different than bone metastates and other bone diseases. Combining scans with x-rays and other imaging modalities can improve the diagnostic accuracy of this disease.


CONCLUSIONS
Radionuclide bone scans are of certain value in the diagnosis of FD. The diagnostic specificity of FD with radionuclide bone scanning can be improved in association with other imaging modalities such as x-rays.
Zhibin
Yuan
Y
Department of Nuclear Medicine, Shanghai 6th People's Hospital, Shanghai Jiaotong University, Shanghai, China. zhibin@yuan.com.cn
Quanyong
Luo
L
Libo
Chen
C
Jun
Zhu
Z
Hankui
Lu
L
Jifang
Zhu
Z
Ruisen
Zhu
Z
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000175:diagnosis / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013669:Technetium Tc 99m Medronate; D014915:Whole-Body Counting / Q000379:methods
D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate