title: Effect of topical bupivacaine on postoperative pain after laparoscopic tubal sterilization with Filshie clips.
abstract: OBJECTIVE
  The purpose of this study was to evaluate postoperative pain after the administration of topical bupivacaine during laparoscopic sterilization with Filshie clips.
  
  
  METHODS
  Sixty-three women who underwent laparoscopic tubal sterilization with Filshie clips were assigned randomly to receive topical bupivacaine or placebo. Presence of pain, pain intensity, nausea, vomiting, timing of request for pain medication, and pain medication requirements were assessed postoperatively.
  
  
  RESULTS
  Patient demographics were similar between the 2 groups. Topical bupivacaine decreased the incidence (P=.005) and intensity (P=.028) of postoperative pain at 30 minutes. No differences in incidence or severity of pain were seen at hospital discharge or on postoperative day 1.
  
  
  CONCLUSIONS
  Topical bupivacaine that is applied to the fallopian tubes at the time of laparoscopic tubal sterilization with the Filshie clip decreases immediate postoperative pain.
authors.affiliation: Departments of Obstetrics and Gynecology and Statistics, University of New Mexico Albuquerque, NM 87131, USA.
authors.forename: Matthew C
authors.initials: MC
authors.lastname: Brennan
authors.forename: Tony
authors.initials: T
authors.lastname: Ogburn
authors.forename: C Javier
authors.initials: CJ
authors.lastname: Hernandez
authors.forename: Clifford
authors.initials: C
authors.lastname: Qualls
mesh_terms: D000287:Administration, Topical; D000328:Adult; D002045:Bupivacaine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods*; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000175:diagnosis* / Q000188:drug therapy*; D011336:Probability; D012016:Reference Values; D012720:Severity of Illness Index; D013246:Sterilization, Tubal / Q000009:adverse effects / Q000295:instrumentation*; D016896:Treatment Outcome
chemical_list: D002045:Bupivacaine