title: [The effects of fibronectin on DNA synthesis and ultrastructure of periodontal ligament cells]
abstract: Microspectrophotometer and transmitted electron microscope (TEM) were used to study the change of DNA synthesis and ultrastructure after fibronection(FN) acted on cultured periodontal ligament cells (PDLC).The results showed that the data of nuclus area,nuclus total absorbs and nuclus mean absorbs of PDLC in FN group was higher than control(P<0.01).Under the TEM we observed that in FN group there were more euchromatin in cell nuclues and more organ cells such as microfilaments,chondriosomes and endoplasmic reticulum in cytoplasm.It suggested that FN can accelerate periodontal regeneration by promoting DNA and protein synthesis of PDLC.
authors.affiliation: The Stomatological College of the Fourth Military Medical University. Xi'an 710032,China.
authors.forename: L
authors.initials: L
authors.lastname: Wan
authors.forename: Z F
authors.initials: ZF
authors.lastname: Wu
authors.forename: Y J
authors.initials: YJ
authors.lastname: Zhou