[Use of clarithromycin in the treatment of atopic dermatitis complicated by staphylococcal infection].
Thirty patients (19 boys and 11 girls) with atopic dermatitis complicated by pyodermia were treated with clarithromycin tablets (Fromilid, KRKA, Slovenia) in a dose of 7.5 mg/kg body weight twice a day. The average treatment course was 7 days. The severity of atopic dermatitis was evaluated by the SCARAD Index. Thirty patients of the reference group were treated with intramuscular lincomycin in a dose of 10-20 mg/kg body weight twice a day for 7 days. The difference in the average SCORAD Index before and after the treatment with clarithromycin amounted to 19.95 vs 14.68 (p < 0.005) with the use of lincomycin. The tolerance of clarithromycin was good.
Gintovt
E A
EA
St. Petersburg State Pediatric Medical Academy, Research Centre of Pharmacotherapy, St. Petersburg.
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D017291:Clarithromycin / Q000627:therapeutic use*; D003876:Dermatitis, Atopic / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011711:Pyoderma / Q000150:complications; D013207:Staphylococcal Skin Infections / Q000150:complications*
D000900:Anti-Bacterial Agents; D017291:Clarithromycin