Molecular characterization of a carbapenem-hydrolyzing class A beta-lactamase, SFC-1, from Serratia fonticola UTAD54.
An environmental isolate of Serratia fonticola resistant to carbapenems contains a gene encoding a class A beta-lactamase with carbapenemase activity. The enzyme was designated SFC-1. The bla(SFC-I) gene is contained in the chromosome of S. fonticola UTAD54 and is absent from other S. fonticola strains.
Henriques
Isabel
I
Center for Cell Biology, Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal.
Moura
Alexandra
A
Alves
Artur
A
Saavedra
Maria José
MJ
Correia
António
A
D000595:Amino Acid Sequence; D001483:Base Sequence; D015780:Carbapenems / Q000378:metabolism*; D002876:Chromosomes, Bacterial / Q000235:genetics; D004269:DNA, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics; D005798:Genes, Bacterial / Q000235:genetics; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D012705:Serratia / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*; D001618:beta-Lactamases / Q000235:genetics* / Q000378:metabolism*
D015780:Carbapenems; D004269:DNA, Bacterial; D001618:beta-Lactamases; C487658:beta-lactamase SFC-1, Serratia fonticola