title: [Myocardial infarction and 5,10-methylenetetrahydro-folate reductase mutation].
abstract: A 40-year-old woman with previous venous thrombosis in the lower limbs had recurrent myocardial infarction in the early puerperium. The only documented risk factor was an elevated level of plasma homocysteine, associated to a heterozygotic anomaly in the enzyme responsible for its metabolism, 5,10-methylenetetrahydrofolate reductase. The case and approaches to treatment are discussed.
authors.affiliation: Servicio de Cardiología, Hospital Madrid Montepríncipe, Boadilla del Monte, Madrid, Spain. frguezrodigo@hotmail.com
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Rodríguez Rodrigo
authors.forename: Juan
authors.initials: J
authors.lastname: Medina
authors.forename: Eddy
authors.initials: E
authors.lastname: Velásquez
authors.forename: Esther
authors.initials: E
authors.lastname: Merino
authors.forename: Juan L
authors.initials: JL
authors.lastname: Delcán
authors.forename: Jose E
authors.initials: JE
authors.lastname: Guerrero
mesh_terms: D000328:Adult; D017023:Coronary Angiography; D005838:Genotype; D006710:Homocysteine / Q000097:blood / Q000235:genetics; D006801:Humans; D008297:Male; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics*; D009154:Mutation; D009203:Myocardial Infarction / Q000097:blood / Q000201:enzymology*
chemical_list: D006710:Homocysteine; D042965:Methylenetetrahydrofolate Reductase (NADPH2)