Selectivity enhancement in the Rh(II)-catalyzed cyclopropanation of styrene with (silanyloxyvinyl)diazoacetates.
The cyclopropanation of styrene with (silanyloxyvinyl)diazoacetates proceeds with exceptional diastereo- and enantioselectivity in the presence of chiral Rh(II) catalysts. 1,8-Naphthoyl-protected amino acids are the most effective Rh(II) ligands for these transformations. [reaction--see text]
Müller
Paul
P
Department of Organic Chemistry, University of Geneva, 30 Quai Ernest Ansermet, CH-1211 Geneva-4, Switzerland. paul.muller@chiorg.unige.ch
Bernardinelli
Gérald
G
Allenbach
Yves F
YF
Ferri
Maria
M
Flack
Howard D
HD