title: Evaluation of isoproterenol in patients undergoing resuscitation for out-of-hospital asystolic cardiac arrest (the Israel Resuscitation with Isoproterenol Study Prospective Randomized Clinical Trial).
abstract: The Israel Resuscitation with Isoproterenol Study included 79 consecutive patients with witnessed out-of-hospital asystolic cardiac arrest who were resuscitated with epinephrine and atropine and randomized to receive additional isoproterenol or no isoproterenol. The rate of return of spontaneous circulation and survival to hospital admission did not differ in patients receiving standard therapy and those receiving additional isoproterenol.
authors.affiliation: The Lady Davis Carmel Medical Center, 7 Michal Street, Haifa 34362, Israel. jaffe@clalit.org
authors.forename: Ronen
authors.initials: R
authors.lastname: Jaffe
authors.forename: Ronen
authors.initials: R
authors.lastname: Rubinshtein
authors.forename: Zvi
authors.initials: Z
authors.lastname: Feigenberg
authors.forename: Eran
authors.initials: E
authors.lastname: Talor
authors.forename: Moshe
authors.initials: M
authors.lastname: Michaelson
authors.forename: Basheer
authors.initials: B
authors.lastname: Karkabi
authors.forename: David A
authors.initials: DA
authors.lastname: Halon
authors.forename: Moshe Y
authors.initials: MY
authors.lastname: Flugelman
authors.forename: Basil S
authors.initials: BS
authors.lastname: Lewis
mesh_terms: D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D000368:Aged; D001285:Atropine / Q000627:therapeutic use; D004837:Epinephrine / Q000627:therapeutic use; D005260:Female; D006323:Heart Arrest / Q000401:mortality / Q000628:therapy*; D006801:Humans; D007545:Isoproterenol / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012151:Resuscitation
chemical_list: D000318:Adrenergic beta-Agonists; D001285:Atropine; D007545:Isoproterenol; D004837:Epinephrine