Syndecans and HIV-1 pathogenesis.
The exploitation of receptors represents a common microbial strategy to survive in the hostile environment of the host. A growing body of evidence suggests that HIV-1 exploits a specific class of receptors-the syndecans-to facilitate colonization of the host.
Gallay
Philippe
P
Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Rd., La Jolla, CA 92037, USA. gallay@scripps.edu
D015658:HIV Infections / Q000821:virology*; D015497:HIV-1 / Q000378:metabolism / Q000472:pathogenicity*; D006497:Heparan Sulfate / Q000378:metabolism; D006801:Humans; D008264:Macrophages / Q000821:virology; D008562:Membrane Glycoproteins / Q000378:metabolism*; D011509:Proteoglycans / Q000378:metabolism*; D015728:Receptors, HIV / Q000378:metabolism; D053667:Syndecans; D013601:T-Lymphocytes / Q000821:virology; D014779:Virus Replication
D006497:Heparan Sulfate; D008562:Membrane Glycoproteins; D011509:Proteoglycans; D015728:Receptors, HIV; D053667:Syndecans