title: Variability in quantitative measurement of the same segment with two different intravascular ultrasound systems: in vivo and in vitro studies.
abstract: We evaluated two different intravascular ultrasound (IVUS) systems, Atlantis and Intrafocus, to verify their accuracy and reproducibility. In an in vivo study on 20 consecutive patients with coronary artery diseases, the minimum lumen diameter (MLD), vessel diameter, lumen area (LA), vessel area, plaque area, and area stenosis rate (% AS) were respectively measured. In an in vitro study, MLD and LA were measured in four metal tubes with different diameters. All of the measured values except for % AS by Atlantis were significantly larger than the values obtained with Intrafocus. Nonuniform rotational distortion (NURD) was estimated as 34% in Atlantis and 1% in Intrafocus. The measurements by Atlantis were larger than the true values while the measurements by Intrafocus were less than the true values in all four metal tubes. These findings suggest that we should clearly avoid the use of different IVUS systems in the same study.
authors.affiliation: Division of Cardiology, Second Department of Medicine, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: Yuxin
authors.initials: Y
authors.lastname: Li
authors.forename: Junko
authors.initials: J
authors.lastname: Honye
authors.forename: Satoshi
authors.initials: S
authors.lastname: Saito
authors.forename: Tadateru
authors.initials: T
authors.lastname: Takayama
authors.forename: Shin-Ichiro
authors.initials: S
authors.lastname: Yokoyama
authors.forename: Tadahiro
authors.initials: T
authors.lastname: Saruya
authors.forename: Motoko
authors.initials: M
authors.lastname: Kotani
authors.forename: Kazuo
authors.initials: K
authors.lastname: Harasawa
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Ando
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Endo
authors.forename: Katsuo
authors.initials: K
authors.lastname: Kanmatsuse
mesh_terms: D000368:Aged; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000453:epidemiology; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000453:epidemiology; D004867:Equipment Design; D005260:Female; D006801:Humans; D007089:Image Enhancement; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D012680:Sensitivity and Specificity; D013223:Statistics as Topic; D018084:Ultrasonography, Interventional