title: Adverse reactions to accidental forearm injection of Bacille Calmette-Guerin vaccine in schoolchildren: 12-month cohort follow-up.
abstract: This study examined the natural history of reaction after accidental intradermal administration of bacille Calmette-Guerin (BCG) vaccine instead of purified protein derivative (PPD) in 226 schoolchildren. At 18 days after vaccination, a local reaction with a diameter of 4.5-14 mm was found in 62% of the students, and ulceration with discharge was found in 26.6%; corresponding rates at 120 days were 72.3% and 38% and at 281 days were 73% and 6%. At 345 days, 85% of the students had a dry scar measuring 5-14 mm in diameter, and none had ulceration or discharge.
authors.affiliation: Ministry of Health, Hasharon District, Israel.
authors.forename: Samuel
authors.initials: S
authors.lastname: Gross
authors.forename: Ernesto
authors.initials: E
authors.lastname: Kahan
authors.forename: Liora
authors.initials: L
authors.lastname: Vesterman
authors.forename: Ofra
authors.initials: O
authors.lastname: Havkin
authors.forename: Alex
authors.initials: A
authors.lastname: Leventhal
mesh_terms: D001500:BCG Vaccine / Q000009:adverse effects*; D002648:Child; D005542:Forearm / Q000473:pathology*; D006801:Humans; D015994:Incidence; D007279:Injections, Subcutaneous; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D012882:Skin Tests
chemical_list: D001500:BCG Vaccine