Stem cells, plasticity and cancer - uncomfortable bed fellows.
Stem cell research is a vibrant and rapidly moving field of science that investigates self-renewing cells in the adult and embryo. Two debates currently exist in the stem cell field concerning the transcriptional redirection of stem cell differentiation and fate, and the reorganization of cell commitment through nuclear reprogramming caused by cell fusion and nuclear transfer. The recent Keystone Symposium in Colorado on stem cells, organised by Fiona Watt and Leonard Zon, brought together both leading and upcoming researchers in the field to explore stem cell biology and these issues.
Trounson
Alan
A
Monash Immunology and Stem Cell Laboratories, Faculty of Medicine, Monash University, Wellington Road, Clayton, Victoria, 3800, Australia.
D000328:Adult; D000818:Animals; D002454:Cell Differentiation; D015179:Colorectal Neoplasms / Q000235:genetics / Q000473:pathology; D004622:Embryo, Mammalian; D018507:Gene Expression Regulation, Developmental; D006410:Hematopoiesis; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000502:physiology*; D006801:Humans; D051379:Mice; D009154:Mutation; D009369:Neoplasms / Q000235:genetics / Q000473:pathology; D012038:Regeneration