Is immune-mediated complete fetal atrioventricular block reversible by transplacental dexamethasone therapy?
We report for the first time a fetal case with sustained regression from isolated complete to first-degree heart block on transplacental treatment with high-dose dexamethasone. Doppler echocardiography is an excellent diagnostic tool in the non-invasive assessment of fetal atrioventricular conduction and its anomalies.
Jaeggi
E T
ET
Division of Cardiology, The Hospital for Sick Children, Toronto, Canada. edgar.jaeggi@sickkids.ca
Silverman
E D
ED
Yoo
S-J
SJ
Kingdom
J
J
D000328:Adult; D003907:Dexamethasone / Q000008:administration & dosage*; D015150:Echocardiography, Doppler / Q000379:methods; D005260:Female; D005312:Fetal Blood / Q000502:physiology; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D005938:Glucocorticoids / Q000008:administration & dosage*; D006327:Heart Block / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000503:physiopathology; D006340:Heart Rate, Fetal / Q000502:physiology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000503:physiopathology; D011247:Pregnancy; D011295:Prenatal Care / Q000379:methods; D016216:Ultrasonography, Prenatal / Q000379:methods*
D005938:Glucocorticoids; D003907:Dexamethasone