Conservative treatment in noninvasive breast cancer.
BACKGROUND
The elective treatment for noninvasive breast carcinoma has not yet been established. As a result of mammographic screening programs, the incidence of noninvasive tumors has increased and has lead to the same controversy already present had with invasive carcinomas: mastectomy or conserving therapy.


METHODS
Since 1990, 101 patients with noninvasive breast cancer were treated with irradiation following breast-conserving surgery. All the patients had irradiation of the whole breast (mean dose, 47.6 +/- 1.2 Gy). The radiation dose boost to the tumor bed was delivered in 28.7% of the cases (mean dose, 21.03 +/- 3.06 Gy), and in 71.3%, the boost was not administered.


RESULTS
With a median follow-up of 34 months, survival is 100%. The disease-free survival at 5 years by the Kaplan-Meier method is 93.6 +/- 8.65.


CONCLUSIONS
The conserving treatment is a valid option for treatment of patients with ductal carcinoma in situ.
Rodríguez
Nuria
N
Institut d'Oncologia Radioterápica, Hospital de l'Esperança, IMAS, Barcelona, Spain. nrodriguez@imas.imim.es
Sanz
Xavier
X
Algara
Manuel
M
Foro
Palmira
P
Auñón
Carmen
C
Morilla
Idoia
I
Reig
Anna
A
Ferrer
Ferran
F
D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D005260:Female; D006801:Humans; D015412:Mastectomy, Segmental; D008875:Middle Aged; D011446:Prospective Studies; D018714:Radiotherapy, Adjuvant; D016019:Survival Analysis; D016896:Treatment Outcome