Polymorphoneutrophilic infiltration in acute interstitial nephritis of Sjögren syndrome.
Sjögren syndrome is a systemic autoimmune disease that involves the kidney as well as other organs. Tubulointerstitial nephritis secondary to monocyte, lymphocyte, and plasma cell infiltration is the characteristic lesion. The authors report a case of Sjögren related acute interstitial nephritis (AIN) with prominent neutrophilic infiltration in the interstitium. This is the first case describing predominance of neutrophilic infiltration in AIN associated with Sjögren syndrome.
Hu
Daniel C
DC
Department of Medicine, University of Virginia, Charlottesville, USA. dch4y@virginia.edu
Cathro
Helen P
HP
Okusa
Mark D
MD
D000328:Adult; D001706:Biopsy; D005260:Female; D006801:Humans; D009395:Nephritis, Interstitial / Q000175:diagnosis / Q000209:etiology / Q000276:immunology* / Q000473:pathology*; D020556:Neutrophil Infiltration; D009504:Neutrophils / Q000276:immunology* / Q000502:physiology; D012859:Sjogren's Syndrome / Q000150:complications / Q000276:immunology* / Q000473:pathology*