title: Reducing motor-vehicle collisions, costs, and fatalities by treating obstructive sleep apnea syndrome.
abstract: OBJECTIVE
  Drivers suffering from obstructive sleep apnea syndrome (OSAS) have an increased risk for being involved in motor-vehicle collisions. This study estimates, for the first time, the annual OSAS-related collisions, costs, and fatalities in the United States and performs a cost-benefit analysis of treating drivers suffering from OSAS with continuous positive airway pressure (CPAP).
  
  
  METHODS
  The MEDLINE-PubMed database (1980 to 2003) was searched for information on OSAS. A meta-analysis was performed of studies investigating the relationship between collisions and OSAS. Data from the National Safety Council were used to estimate OSAS-related collisions, costs, and fatalities and their reduction with treatment. Next, the annual cost of treating OSAS with CPAP was calculated. Finally, multiple 1-way sensitivity analyses were performed.
  
  
  METHODS
  N/A.
  
  
  METHODS
  N/A.
  
  
  METHODS
  N/A.
  
  
  RESULTS
  More than 800,000 drivers were involved in OSAS-related motor-vehicle collisions in the year 2000. These collisions cost 15.9 billion dollars and 1,400 lives in the year 2000. In the United States, treating all drivers suffering from OSAS with CPAP would cost 3.18 billion dollars, save 11.1 billion dollars in collision costs, and save 980 lives annually.
  
  
  CONCLUSIONS
  Annually, a small but significant portion of motor-vehicle collisions, costs, and deaths are related to OSAS. With CPAP treatment, most of these collisions, costs, and deaths can be prevented. Treatment of OSAS benefits both the patient and the public.
authors.affiliation: University of California, San Diego, School of Medicine Department of Radiology, 92103-8765, USA. asassani@ucsd.edu
authors.forename: Alex
authors.initials: A
authors.lastname: Sassani
authors.forename: Larry J
authors.initials: LJ
authors.lastname: Findley
authors.forename: Meir
authors.initials: M
authors.lastname: Kryger
authors.forename: Eric
authors.initials: E
authors.lastname: Goldlust
authors.forename: Charles
authors.initials: C
authors.lastname: George
authors.forename: Terence M
authors.initials: TM
authors.lastname: Davidson
mesh_terms: D000063:Accidents, Traffic / Q000191:economics / Q000401:mortality / Q000517:prevention & control; D000328:Adult; D001334:Automobile Driving / Q000706:statistics & numerical data*; D003365:Costs and Cost Analysis; D006970:Disorders of Excessive Somnolence / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D011175:Positive-Pressure Respiration / Q000191:economics* / Q000379:methods*; D012680:Sensitivity and Specificity; D020181:Sleep Apnea, Obstructive / Q000191:economics / Q000453:epidemiology / Q000628:therapy