[The antibacterial efficacy to obligate anaerobes isolated from the infected root canal of deciduous teeth]
TMJ osteoarthrosis(OA) is frequently seen in the Oral and Maxillofacial Surgery clinics.In order to investigate cellular and molecular basis of the pathogenesis of TMJOA,the levels of IL-1 and IL-6 in synovial aspirates from different stages of TMJOA patients were determined and analysed.It was found that both of them were highly correlated with the severity of TMJOA(P<0.0001).A positive linear correlation was also found between IL-1 and IL-6(P<0.0001).The balance and imbalance between MMPs and TIMPS and the modulatory mechanism of cytokines were introduced and their possible roles in the pathogenesis of TMJOA were discussed.
Hu
B
B
Department of Oral Maxillofacial Surgery,College of Stomatology, West China University of Medical Sciences. Chengdu 610041,China.
Huang
D Z
DZ
Yu
R
R
Peng
G P
GP
Zhang
C J
CJ