[Development of new technology for isolation of nebramycin complex antibiotics from the cultural fluid].
A new technology for nebramycin complex antibiotics isolation from non-filtered culture fluid was developed. The industrial use of the technology permitted to exclude the stage of the culture fluid filtration, to increase the yield by more than 33% and to reduce the time of the process by 1.7 times.
Nogovitsyna
L V
LV
Mikhaĭlov
V A
VA
Kharechko
A T
AT
Sadovoĭ
N V
NV
D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000302:isolation & purification*; D003470:Culture Media; D005285:Fermentation; D007475:Ion Exchange Resins; D009328:Nebramycin / Q000096:biosynthesis / Q000302:isolation & purification*; D013302:Streptomyces / Q000254:growth & development / Q000378:metabolism
D000900:Anti-Bacterial Agents; D003470:Culture Media; D007475:Ion Exchange Resins; D009328:Nebramycin