Hematopoietic effect of ginsenoside Rg3 in ICR mouse primary cultures and its application to a biological response modifier.
Ginsenoside Rg3, which is obtained as a by-product during the steaming of red ginseng, at 300 microg/ml enhanced the proliferation of the total spleen and bone marrow (BM) cells in both the cyclophosphamide (CYC)-treated and non-CYC-treated groups.
Joo
S S
SS
Department of Immunology, College of Pharmacy, Chung-Ang University, Seoul 156-756, South Korea.
Won
T J
TJ
Kim
M S
MS
Lee
D I
DI
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001854:Bone Marrow Cells / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects*; D003520:Cyclophosphamide; D017931:DNA Primers; D036145:Ginsenosides / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D005894:Panax; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D016133:Polymerase Chain Reaction; D013154:Spleen / Q000166:cytology / Q000187:drug effects*
D000972:Antineoplastic Agents, Phytogenic; D017931:DNA Primers; D036145:Ginsenosides; D010936:Plant Extracts; C097367:ginsenoside Rg3; D003520:Cyclophosphamide