Epitheloid angiosarcoma of the splenic capsula as a result of foreign body tumorigenesis. A case report.
A case of an epitheloid angiosarcoma of the splenic capsula is reported. This tumour developed in close relation to a gauze sponge, which was accidentally left behind 38 years earlier during a left-sided nephrectomy. The tumour probably arose from pluripotential mesothelial stem cells within the splenic capsula, with subsequent mesothelial to endothelial metaplasia and neoplastic transformation. Clinical, radiological, peroperative and pathological features of this angiosarcoma add to the validity of the concept of inert foreign body tumorigenesis.
Keymeulen
K
K
Department of General Paediatric, AZ St.-Jan, Brugge, Belgium.
Dillemans
B
B
D000368:Aged; D002471:Cell Transformation, Neoplastic; D015622:Epithelioid Cells; D017809:Fatal Outcome; D005547:Foreign Bodies / Q000150:complications*; D006394:Hemangiosarcoma / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008297:Male; D009392:Nephrectomy; D011183:Postoperative Complications; D013156:Splenectomy / Q000379:methods; D013160:Splenic Neoplasms / Q000209:etiology* / Q000503:physiopathology; D015503:Surgical Sponges / Q000009:adverse effects*