N-acetyl-beta-D-glucosaminidase activity in urine of dental personnel.
BACKGROUND
Dental personnel is exposed to several potential nephrotoxic agents. Urinary N-acetyl-beta-d-glucosaminidase (U-NAG) activity has emerged as a sensitive marker of early nephrotoxicity.


METHODS
U-NAG was evaluated, by fluorimetric assay, in urine from 30 healthy subjects and 30 dental personnels.


RESULTS
The median value of U-NAG activity (133.5 U/mmol urinary creatinine (U-Cr) in urines of dental personnel was not statistically different (P>0.05) from activity (100.7 U/mmol U-Cr) of control urines.


CONCLUSIONS
The results suggest that, for dental personnel, exposure to potential nephrotoxic agents is not usually high enough to increase U-NAG activity.
Tassi
C
C
Dipartimento di Scienze Biochimiche e Biotecnologie Molecolari, Sezione di Medicina di Laboratorio, Università degli Studi di Perugia, Perugia, Italy.
Mancuso
F
F
Lomurno
G
G
Lotito
M
M
Feligioni
L
L
De Bellis
F
F
Eramo
S
S
Capodicasa
E
E
D000118:Acetylglucosaminidase / Q000652:urine*; D000328:Adult; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000209:etiology; D003797:Dental Staff; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced / Q000175:diagnosis; D008297:Male; D016555:Matched-Pair Analysis; D008875:Middle Aged; D016273:Occupational Exposure / Q000032:analysis*
D000118:Acetylglucosaminidase