title: Electrodiagnostic evaluation in feline hypertrophic muscular dystrophy.
abstract: Standard needle electromyography (EMG) of 56 muscles and nerve conduction velocities (NCV) of the ulnar and common peroneal nerves were investigated in each of six cats affected with hypertrophic feline muscular dystrophy, 10 related heterozygote carriers and 10 normal cats. The EMG findings were considered normal in carrier and control cats, and consisted of 33% normal readings, 22% myotonic discharges, 18% fibrillation potentials, 11% prolonged insertional potentials, 10% complex repetitive discharges and 6% positive sharp waves in affected cats. Muscles of the proximal limbs were most frequently affected. No differences in NCV were found between the three cat groups. It was concluded that dystrophin-deficient dystrophic cats have widespread and frequent EMG changes, predominantly myotonic discharges and fibrillation potentials, which are most pronounced in the proximal appendicular muscles.
authors.affiliation: Department of Small Animal Internal Medicine, Klinik für Kleine Haustiere, University of Berne, Länggassstrasse 128, 3012 Bern, Switzerland.
authors.forename: J
authors.initials: J
authors.lastname: Howard
authors.forename: A
authors.initials: A
authors.lastname: Jaggy
authors.forename: A
authors.initials: A
authors.lastname: Busato
authors.forename: F
authors.initials: F
authors.lastname: Gaschen
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis*; D002415:Cats; D004576:Electromyography / Q000662:veterinary*; D005260:Female; D008297:Male; D018482:Muscle, Skeletal / Q000502:physiology*; D009137:Muscular Dystrophy, Animal / Q000175:diagnosis*; D010375:Pedigree