title: [Gene polymorphism of xenobiotics in workers of petroleum and chemical industry].
abstract: Increasing use of aromatic hydrocarbons and their derivatives, known mutagens and carcinogens, in petrochemistry leads to higher number of workers having occupational contact with those chemicals. Most alien chemicals (xenobiotics) incorporated into human body do not demonstrate direct biological effects but undergo various biologic transformations. Humans proved to have genetic control over metabolism of xenobiotics entering the body, so various individuals depending on genetic features could be resistant or otherwise be extremely sensitive to chemical agents.
authors.forename: O V
authors.initials: OV
authors.lastname: Makarova
authors.forename: L K
authors.initials: LK
authors.lastname: Karimova
authors.forename: G G
authors.initials: GG
authors.lastname: Gimranova
authors.forename: S Kh
authors.initials: SKh
authors.lastname: Churmantaeva
authors.forename: T V
authors.initials: TV
authors.lastname: Viktorova
mesh_terms: D000328:Adult; D000368:Aged; D000395:Air Pollutants, Occupational / Q000493:pharmacokinetics*; D000483:Alleles; D019363:Cytochrome P-450 CYP1A1 / Q000235:genetics*; D004247:DNA / Q000032:analysis; D019652:Extraction and Processing Industry; D005260:Female; D017353:Gene Deletion; D005787:Gene Frequency / Q000235:genetics; D005982:Glutathione Transferase / Q000235:genetics*; D006801:Humans; D008658:Inactivation, Metabolic / Q000235:genetics; D008297:Male; D008875:Middle Aged; D010578:Petroleum; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012426:Russia; D017132:Workplace / Q000592:standards; D015262:Xenobiotics / Q000493:pharmacokinetics*
chemical_list: D000395:Air Pollutants, Occupational; D019363:Cytochrome P-450 CYP1A1; D004247:DNA; D005982:Glutathione Transferase; D010578:Petroleum; D015262:Xenobiotics