A facile access to chiral 4-isopropyl-, 4-benzyl-, and 4-phenyloxazolidine-2-thione.
A highly practical procedure for preparing the chiral oxazolidine-2-thione auxiliaries using carbon disulfide and the corresponding chiral amino alcohols as the starting materials in the presence of potassium carbonate and hydrogen peroxide is presented.
Wu
Yikang
Y
State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China. yikangwu@mail.sioc.ac.cn
Yang
Yong-Qing
YQ
Hu
Qi
Q