title: High resolution anoscopy findings for men who have sex with men: inaccuracy of anal cytology as a predictor of histologic high-grade anal intraepithelial neoplasia and the impact of HIV serostatus.
abstract: We compared the pathological diagnoses obtained by anal Papanicolaou (Pap) smear with those obtained by anal biopsy or by surgical excision for 153 men who have sex with men (MSM). Analysis of these paired specimens showed that anal Pap smears were an inaccurate predictor of high-grade anal dysplasia, regardless of human immunodeficiency virus (HIV) serostatus. The presence of any abnormal anal cytological finding indicates a potential for high-grade dysplasia on histological examination of MSM.
authors.affiliation: Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA. lpanther@bidmc.harvard.edu
authors.forename: Lori A
authors.initials: LA
authors.lastname: Panther
authors.forename: Katiri
authors.initials: K
authors.lastname: Wagner
authors.forename: JoAnn
authors.initials: J
authors.lastname: Proper
authors.forename: Dana K
authors.initials: DK
authors.lastname: Fugelso
authors.forename: Pamela A
authors.initials: PA
authors.lastname: Chatis
authors.forename: Will
authors.initials: W
authors.lastname: Weeden
authors.forename: Imad A
authors.initials: IA
authors.lastname: Nasser
authors.forename: John P
authors.initials: JP
authors.lastname: Doweiko
authors.forename: Bruce J
authors.initials: BJ
authors.lastname: Dezube
mesh_terms: D001004:Anus Diseases / Q000453:epidemiology / Q000473:pathology; D001005:Anus Neoplasms / Q000453:epidemiology / Q000473:pathology*; D001706:Biopsy; D006679:HIV Seropositivity; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D065006:Papanicolaou Test