title: N-acetyl-beta-D-glucosaminidase activity in urine of dental personnel.
abstract: BACKGROUND
  Dental personnel is exposed to several potential nephrotoxic agents. Urinary N-acetyl-beta-d-glucosaminidase (U-NAG) activity has emerged as a sensitive marker of early nephrotoxicity.
  
  
  METHODS
  U-NAG was evaluated, by fluorimetric assay, in urine from 30 healthy subjects and 30 dental personnels.
  
  
  RESULTS
  The median value of U-NAG activity (133.5 U/mmol urinary creatinine (U-Cr) in urines of dental personnel was not statistically different (P>0.05) from activity (100.7 U/mmol U-Cr) of control urines.
  
  
  CONCLUSIONS
  The results suggest that, for dental personnel, exposure to potential nephrotoxic agents is not usually high enough to increase U-NAG activity.
authors.affiliation: Dipartimento di Scienze Biochimiche e Biotecnologie Molecolari, Sezione di Medicina di Laboratorio, Università degli Studi di Perugia, Perugia, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Tassi
authors.forename: F
authors.initials: F
authors.lastname: Mancuso
authors.forename: G
authors.initials: G
authors.lastname: Lomurno
authors.forename: M
authors.initials: M
authors.lastname: Lotito
authors.forename: L
authors.initials: L
authors.lastname: Feligioni
authors.forename: F
authors.initials: F
authors.lastname: De Bellis
authors.forename: S
authors.initials: S
authors.lastname: Eramo
authors.forename: E
authors.initials: E
authors.lastname: Capodicasa
mesh_terms: D000118:Acetylglucosaminidase / Q000652:urine*; D000328:Adult; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000209:etiology; D003797:Dental Staff; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced / Q000175:diagnosis; D008297:Male; D016555:Matched-Pair Analysis; D008875:Middle Aged; D016273:Occupational Exposure / Q000032:analysis*
chemical_list: D000118:Acetylglucosaminidase