[Multiple endocrine neoplasia].
A 69-year-old female having a large left adrenal mass and a nodular lesion in thyroid gland was admitted to the hospital. Endocrinologically she showed high levels of plasma ACTH and cortisol, which were not suppressed by high dose dexamethasone, elevated serum parathyroid hormone and markedly increased daily urinary excretion of catecholamines. She died of sepsis, and postmortem examination was performed. A left adrenal pheochromocytoma, which was immunohistochemically proven to be ACTH producing, a papillary thyroid carcinoma and parathyroid adenomas were found. To our knowledge this is the first report of coexistence of these three endocrine tumors in a single patient.
Saito
Tatsuya
T
Department of Internal Medicine, Yokosuka Kyousai Hospital.
D000236:Adenoma / Q000175:diagnosis* / Q000473:pathology; D000310:Adrenal Gland Neoplasms / Q000175:diagnosis / Q000473:pathology; D000368:Aged; D002291:Carcinoma, Papillary / Q000175:diagnosis / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D009377:Multiple Endocrine Neoplasia / Q000175:diagnosis* / Q000473:pathology; D010282:Parathyroid Neoplasms / Q000175:diagnosis / Q000473:pathology; D010673:Pheochromocytoma / Q000175:diagnosis / Q000473:pathology; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000473:pathology