title: A medicinal chemistry perspective on artemisinin and related endoperoxides.
authors.affiliation: Department of Chemistry, The Robert Robinson Laboratories, University of Liverpool, Liverpool L69 7ZD, U.K. p.m.oneill01@liv.ac.uk
authors.forename: Paul M
authors.initials: PM
authors.lastname: O'Neill
authors.forename: Gary H
authors.initials: GH
authors.lastname: Posner
mesh_terms: D000478:Alkylation; D000962:Antimalarials / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D037621:Artemisinins / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D015853:Cysteine Proteinase Inhibitors / Q000737:chemistry / Q000627:therapeutic use; D004351:Drug Resistance; D004355:Drug Stability; D004359:Drug Therapy, Combination; D006418:Heme / Q000378:metabolism; D006801:Humans; D016778:Malaria, Falciparum / Q000188:drug therapy; D018384:Oxidative Stress; D011355:Prodrugs / Q000737:chemistry / Q000627:therapeutic use; D012717:Sesquiterpenes / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D000962:Antimalarials; D037621:Artemisinins; D015853:Cysteine Proteinase Inhibitors; D011355:Prodrugs; D012717:Sesquiterpenes; D006418:Heme; C031327:artemisinin