[Morphological changes in testicular tissue in clean-up personnel after the Chernobyl nuclear reactor accident].
Pathomorphological alterations of testicular tissue were absent in men exposed to total body ionizing radiation in the dose of 1 to 10 cGy. Some changes in seminiferous tubules appeared in the dose of 10 to 20 cGy. Lymphoid infiltration of the seminiferous tubules arose 5 years after the accident and of the interstitial tissue--10-15 years after the radiation in exposure in the dose 20-30 cGy. Autoimmune orchitis affects spermatogenesis early after irradiation. Lymphoid infiltration of the seminiferous tubules and interstitial tissue is observed 5 years after radiation in the dose 30 to 50 cGy. Sclerosis of 50% seminiferous tubules, foci of regeneration of Leydig cells with lymphoid infiltration and interstitial fibrosis takes place 10-15 years after irradiation.
Cheburakov
B Iu
BIu
Regional Hospital, 350086, Krasnodar.
Cheburakov
S Iu
SIu
Belozerov
N Iu
NIu
D004307:Dose-Response Relationship, Radiation; D005355:Fibrosis / Q000473:pathology; D006801:Humans; D007985:Leydig Cells / Q000473:pathology / Q000528:radiation effects; D008297:Male; D016273:Occupational Exposure / Q000009:adverse effects*; D009920:Orchitis / Q000473:pathology; D011829:Radiation Dosage; D018788:Radioactive Hazard Release; D012189:Retrospective Studies; D012598:Sclerosis / Q000473:pathology; D012671:Seminiferous Tubules / Q000473:pathology / Q000528:radiation effects; D013091:Spermatogenesis / Q000528:radiation effects; D013737:Testis / Q000473:pathology* / Q000528:radiation effects; D014455:Ukraine