title: Vesicular glutamate transporter immunoreactivity in the central and peripheral endings of muscle-spindle afferents.
abstract: Expression of vesicular glutamate transporters (VGLUTs: VGLUT1, VGLUT2 and VGLUT3) in muscle spindle afferents was examined in rats. VGLUT1 immunoreactivity was detected in the sensory endings on the equatorial and juxta-equatarial regions of intrafusal fibers as well as in many axon terminals within lamina IX of the spinal cord. VGLUT1 might be expressed not only in the central axon terminals but also in the peripheral sensory endings of muscle-spindle afferents.
authors.affiliation: Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.
authors.forename: Sheng-Xi
authors.initials: SX
authors.lastname: Wu
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Koshimizu
authors.forename: Yu-Peng
authors.initials: YP
authors.lastname: Feng
authors.forename: Keiko
authors.initials: K
authors.lastname: Okamoto
authors.forename: Fumino
authors.initials: F
authors.lastname: Fujiyama
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Hioki
authors.forename: Yun-Qing
authors.initials: YQ
authors.lastname: Li
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kaneko
authors.forename: Noboru
authors.initials: N
authors.lastname: Mizuno
mesh_terms: D000344:Afferent Pathways / Q000378:metabolism* / Q000648:ultrastructure; D026922:Amino Acid Transport Systems, Acidic / Q000378:metabolism*; D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism*; D002795:Choline O-Acetyltransferase / Q000378:metabolism; D007839:Functional Laterality; D007150:Immunohistochemistry; D008297:Male; D026901:Membrane Transport Proteins; D016253:Microscopy, Immunoelectron / Q000379:methods; D009470:Muscle Spindles / Q000378:metabolism* / Q000648:ultrastructure; D051381:Rats; D017208:Rats, Wistar; D013569:Synapses / Q000378:metabolism / Q000648:ultrastructure; D050598:Vesicular Glutamate Transport Protein 1; D050599:Vesicular Glutamate Transport Protein 2; D050496:Vesicular Glutamate Transport Proteins; D033921:Vesicular Transport Proteins
chemical_list: D026922:Amino Acid Transport Systems, Acidic; D002352:Carrier Proteins; D026901:Membrane Transport Proteins; C493475:Slc17a6 protein, rat; C493466:Slc17a7 protein, rat; C482103:Slc17a8 protein, rat; D050598:Vesicular Glutamate Transport Protein 1; D050599:Vesicular Glutamate Transport Protein 2; D050496:Vesicular Glutamate Transport Proteins; D033921:Vesicular Transport Proteins; D002795:Choline O-Acetyltransferase