[NO-dependent effects during adaptation of rats to intermittent hypoxia].
In experiments on Wistar rats processes nitric oxide production on concentration of anions (NO2-, NO3-), carbamide and polyamines contents were investigated in processes of rats adaptation to acute hypoxia (7% O2 in N2, 30 min) and intermittent hypoxia training (10% O2 in N2, 15 min, 5 cycles daily) during 14 days. NO production by oxygen-dependent and oxygen-independent metabolites paths has been investigated. It is concluded that the disturbances in nitric oxide system induced by acute hypoxia by L-arginine injections may result in acute hypoxia.
Kurhaliuk
N M
NM
Ivan Franko Lviv National University, Lviv, Ukraine. kurhalyuk@ukr.net
Kotsiuruba
A V
AV
Bukhanevych
O M
OM
Kosiakova
H V
HV
D000222:Adaptation, Physiological; D000818:Animals; D001120:Arginine / Q000494:pharmacology; D000860:Hypoxia / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008297:Male; D009569:Nitric Oxide / Q000096:biosynthesis* / Q000097:blood; D009573:Nitrites / Q000032:analysis; D051381:Rats; D017208:Rats, Wistar
D009573:Nitrites; D009569:Nitric Oxide; D001120:Arginine