Prospective surveillance study for risk factors of central venous catheter-related bloodstream infections.
OBJECTIVE
Risk factors of catheter-related bloodstream infection (CR-BSI) caused by central venous catheter (CVC) use at a university hospital were evaluated.


METHODS
A prospective, observational, hospital-wide study was conducted.


METHODS
The study was conducted at a university hospital with 1050 beds.


METHODS
Nontunneled catheters were used, and double or triple lumen was observed. Catheters were cultured by semi-quantitative method, and blood cultures were performed if necessary. All epidemiologic and clinical data were recorded without intervention during the study.


RESULTS
Over a 1-year period, the study assessed 389 CVCs inserted in 367 patients (mean age 50.9 +/- 18.1 years; 215 [58.6%] men, 152 [41.4%] women). Duration of catheterization was 12.0 +/- 9.9 days. CVCs were inserted into either the subclavian vein (N=263; 67.6%) or the jugular vein (N=128; 32.4%). In 250 episodes (64.3%), antibiotics were used concomitantly. CR-BSI was found in 43 of all CVCs (11.1%). The rate of CR-BSI per 1000 catheter-days was 9.21 for the whole cohort. In multivariable analysis, only renal failure (OR 4.83; CI 1.32-17.66; P=.017) was found to be a risk factor for CR-BSI.


CONCLUSIONS
Renal failure was an independent risk factor for CR-BSI.
Hosoglu
Salih
S
Clinic of Microbiology and Infection, Dicle University Hospital, 21280 Diyarbakir, Turkey.
Akalin
Serife
S
Kidir
Veysel
V
Suner
Ali
A
Kayabas
Hasan
H
Geyik
Mehmet Faruk
MF
D016470:Bacteremia / Q000453:epidemiology* / Q000209:etiology; D017848:Blood-Borne Pathogens; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D003428:Cross Infection / Q000453:epidemiology* / Q000209:etiology; D004866:Equipment Contamination; D005260:Female; D006785:Hospitals, University; D006801:Humans; D015994:Incidence; D017053:Infection Control / Q000592:standards*; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D011446:Prospective Studies; D012307:Risk Factors; D014421:Turkey / Q000453:epidemiology