Expression analysis of the Drosophila pipsqueak family members fernández/distal antenna and hernández/distal antenna related.
The "pipsqueak" family is composed of proteins that contain a pipsqueak motif, a previously characterised DNA binding domain, and thus represents a new family of potential transcription factors. Previous functional characterisation of several Drosophila genes encoding pipsqueak domain-containing proteins has shown their crucial role in development. Here, I report the embryonic, larval, and pupal expression pattern of two Drosophila genes, fernández/distal antenna and hernández/distal antenna related, which encode protein members of the pipsqueak family with similar pipsqueak motifs. Furthermore, I show that, consistently with their expression pattern, these two genes are required in the nervous system during the embryonic development.
Suzanne
Magali
M
Centro de Biología Molecular Severo Ochoa, Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain. msuzanne@cbm.uam.es
D000818:Animals; D002490:Central Nervous System / Q000196:embryology / Q000378:metabolism; D004330:Drosophila / Q000196:embryology / Q000235:genetics* / Q000254:growth & development* / Q000378:metabolism; D029721:Drosophila Proteins / Q000235:genetics* / Q000378:metabolism*; D047108:Embryonic Development; D005136:Eye Proteins / Q000235:genetics* / Q000378:metabolism*; D018507:Gene Expression Regulation, Developmental; D007814:Larva / Q000235:genetics / Q000378:metabolism; D010641:Phenotype; D011679:Pupa / Q000235:genetics / Q000378:metabolism; D034622:RNA Interference; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism
D029721:Drosophila Proteins; D005136:Eye Proteins; D012333:RNA, Messenger; C477647:fernandez protein, Drosophila; C477646:hernandez protein, Drosophila