Patterns of practice in the United States: insights from CaPSURE on prostate cancer management.
The Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE) is a national disease registry of more than 10,000 patients with prostate cancer treated at 31 primarily community-based sites across the country. The database tracks oncologic and health-related quality-of-life outcomes. Because the urologists participating in the project treat according to their usual practices, CaPSURE facilitates the study of trends in disease-management strategies, offering a reflection of "real world" practice patterns. This review highlights key studies during the past several years that document downward risk migration, validates widely used prognostic nomograms, establishes prostate-specific antigen doubling time as a surrogate endpoint for disease-specific mortality, assesses the impact of treatment on patient-reported quality of life, and presents national trends in imaging test use and primary treatment strategies for localized disease.
Cooperberg
Matthew R
MR
University of California, San Francisco, Mount Zion Cancer Center, 1600 Divisadero Street, 6th Floor, San Francisco, CA 94115-1711, USA.
Broering
Jeanette M
JM
Latini
David M
DM
Litwin
Mark S
MS
Wallace
Katrine L
KL
Carroll
Peter R
PR
D006801:Humans; D008297:Male; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D011471:Prostatic Neoplasms / Q000628:therapy*; D012042:Registries / Q000706:statistics & numerical data*; D014481:United States