title: Efficacy of endoscopic wire guided biliary brushing in the evaluation of biliary strictures.
abstract: Endoscopic brush cytology is a valuable technique for the evaluation of biliary strictures. The sensitivity of this technique varies from 30% to 83%, however, it can have specificity of 100%. We retrospectively evaluated the usefulness of wire-guided biliary brush cytology in biliary strictures in our hospital over a 3 years period from 1997 to 2000. Brushings from 58 biliary strictures were obtained during endoscopic retrograde cholangiography. They were compared with histological proof obtained by surgical biopsy or percutaneous fine-needle aspiration cytology and/or clinical findings. These were reported as benign or malignant. Eleven patients were excluded due to incomplete data. Eighteen patients had benign brushings. Fourteen of the 29 patients in whom histological confirmation of malignancy brushings was obtained were also reported as malignant. The sensitivity of endoscopic brushings was 48.2%, specificity 100% and diagnostic accuracy 55.2%. No major complications were seen in our study group.
authors.affiliation: Department of Medicine, Cytology and Radiology, Government Medical College and Hospital, Chandigarh, India. atulsachdev@glide.net.in
authors.forename: A
authors.initials: A
authors.lastname: Sachdev
authors.forename: A
authors.initials: A
authors.lastname: Duseja
authors.forename: A
authors.initials: A
authors.lastname: Bhalla
authors.forename: U
authors.initials: U
authors.lastname: Handa
authors.forename: B S
authors.initials: BS
authors.lastname: Sandhu
authors.forename: V
authors.initials: V
authors.lastname: Gupta
authors.forename: S
authors.initials: S
authors.lastname: Kochhar
mesh_terms: D001650:Bile Duct Neoplasms / Q000150:complications / Q000473:pathology*; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods*; D002779:Cholestasis / Q000209:etiology / Q000473:pathology*; D006801:Humans; D010190:Pancreatic Neoplasms / Q000150:complications / Q000473:pathology*; D012189:Retrospective Studies; D012680:Sensitivity and Specificity