title: Sleep disorders and illness intrusiveness in patients on chronic dialysis.
abstract: BACKGROUND
  The prevalence of sleep problems (insomnia, restless legs syndrome, periodic limb movements in sleep and sleep apnoea) has been shown to be high in patients with end-stage renal disease (ESRD) and might contribute to impaired quality of life in this population.
  
  
  METHODS
  In a cross-sectional study using self-administered questionnaires, we examined the prevalence of sleep disorders and assessed their effect on different aspects of health-related quality of life in a sample of Hungarian patients on maintenance dialysis.
  
  
  RESULTS
  Our data confirm that sleep problems are frequent in patients with ESRD; 65% of the patients reported symptoms of at least one specific sleep disorder; insomnia was the most common sleep complaint with 49%, the prevalence of sleep apnoea was 32% and the prevalence of restless legs syndrome was 15%. Co-morbidity, assessed by the End-Stage Renal Disease Severity Index, was shown to be an independent predictor of sleep disorders. Patients with sleep disorders reported higher illness intrusiveness and worse self-perceived health than those without sleep problems. The presence of sleep disorders was an independent predictor of illness intrusiveness, an important determinant of health-related quality of life.
  
  
  CONCLUSIONS
  Sleep disorders are important determinants of illness intrusiveness and health-related quality of life in patients with ESRD. Sleep problems may be treated successfully; therefore, more attention should be paid to assessing these problems in this patient population.
authors.affiliation: 1st Department of Internal Medicine, Semmelweiss University Budapest. mucsist@net.sote.hu
authors.forename: Istvan
authors.initials: I
authors.lastname: Mucsi
authors.forename: Miklos Zs
authors.initials: MZ
authors.lastname: Molnar
authors.forename: Janos
authors.initials: J
authors.lastname: Rethelyi
authors.forename: Eszter
authors.initials: E
authors.lastname: Vamos
authors.forename: Gabor
authors.initials: G
authors.lastname: Csepanyi
authors.forename: Gyorgyi
authors.initials: G
authors.lastname: Tompa
authors.forename: Szabolcs
authors.initials: S
authors.lastname: Barotfi
authors.forename: Adrienn
authors.initials: A
authors.lastname: Marton
authors.forename: Marta
authors.initials: M
authors.lastname: Novak
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D006435:Renal Dialysis; D012893:Sleep Wake Disorders / Q000453:epidemiology / Q000209:etiology*; D011795:Surveys and Questionnaires