title: Pulmonary dirofilariasis with serologic study on familial infection with Dirofilaria immitis.
abstract: An asymptomatic patient with a pulmonary coin lesion surgically diagnosed with pulmonary dirofilariasis caused by infection with Dirofilaria immitis (D. immitis) is presented. The preoperative stored serum of the patient was positive for D. immitis by enzyme-linked immunosorbent assay (ELISA). A family study showed that three of five family members were seropositive for D. immitis. These results suggest that family members of a patient with pulmonary dirofilariasis were frequently exposed to D. immitis and serodiagnostic methods are useful for detecting subclinical infection of D. immitis.
authors.affiliation: Third Department of Internal Madicine, Kagoshima University School of Madicine, Kagoshima.
authors.forename: Shin-ichiro
authors.initials: S
authors.lastname: Mori
authors.forename: Yasunobu
authors.initials: Y
authors.lastname: Hirotsu
authors.forename: Akira
authors.initials: A
authors.lastname: Mizoguchi
authors.forename: Masaharu
authors.initials: M
authors.lastname: Kawabata
authors.forename: Fukumi
authors.initials: F
authors.lastname: Nakamura-Uchiyama
authors.forename: Yukifumi
authors.initials: Y
authors.lastname: Nawa
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Osame
mesh_terms: D000293:Adolescent; D000328:Adult; D000909:Antibodies, Helminth / Q000097:blood; D000947:Antigens, Helminth / Q000097:blood; D002648:Child; D004184:Dirofilariasis / Q000097:blood* / Q000235:genetics* / Q000601:surgery; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008174:Lung Diseases, Parasitic / Q000097:blood* / Q000235:genetics* / Q000601:surgery; D008297:Male
chemical_list: D000909:Antibodies, Helminth; D000947:Antigens, Helminth