Carbohydrate-deficient transferrin: a marker of alcohol abuse.
Serum carbohydrate-deficient transferrin (CDT) measurement is valuable for the identification of chronic excess alcohol consumption. CDT is increased in serum in approximately 50% of those classed as heavy drinkers and 70-80% of those defined as alcoholics. With abstinence, the serum CDT concentration reverts towards normal within approximately 2 weeks. Specificity for alcohol abuse ranges from 80 to 95% in the general population and from 70 to 80% in liver clinic patients.
Rosalki
S B
SB
OmniLabs, London, UK.
D000437:Alcoholism / Q000175:diagnosis* / Q000235:genetics; D015415:Biomarkers / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D012680:Sensitivity and Specificity; D014168:Transferrin / Q000031:analogs & derivatives* / Q000032:analysis* / Q000235:genetics
D015415:Biomarkers; D014168:Transferrin; C056759:carbohydrate-deficient transferrin