title: Heterozygosities and allelic frequencies of 811 dinucleotide-repeat marker loci in the Taiwanese population.
abstract: To evaluate basic informativeness of commercially available microsatellite markers in theTaiwanese population, 190 unrelated Taiwanese children were genotyped using ABI PRISM Linkage Mapping Set-HD5. The average heterozygosity in Taiwanese was slightly lower than that in Caucasians among these 811 microsatellite markers. There were 50 marker loci with heterozygosities lower than 50%. Moreover, allelic distributions at many of the loci were significantly different in two ethnic groups. The results reported here represent a valuable database for disease genes mapping in the Taiwanese population. This database can be easily accessed at the Web site of Vita Genomics, Inc. (http://www.vitagenomics.com/str.html).
authors.affiliation: STR Genotyping Laboratory, Research and Development Division, Vita Genomics, Inc., 7Fl., No. 6, Sec. 1, Jungshing Rd, Wugu Shiang, Taipei County, 248, Taiwan.
authors.forename: Cheng-Hsin
authors.initials: CH
authors.lastname: Lu
authors.affiliation: STR Genotyping Laboratory, Research and Development Division, Vita Genomics, Inc., 7Fl., No. 6, Sec. 1, Jungshing Rd, Wugu Shiang, Taipei County, 248, Taiwan.
authors.forename: Cherry Guan-Ju
authors.initials: CG
authors.lastname: Lin
authors.affiliation: STR Genotyping Laboratory, Research and Development Division, Vita Genomics, Inc., 7Fl., No. 6, Sec. 1, Jungshing Rd, Wugu Shiang, Taipei County, 248, Taiwan.
authors.forename: Lichih
authors.initials: L
authors.lastname: Huang
authors.affiliation: STR Genotyping Laboratory, Research and Development Division, Vita Genomics, Inc., 7Fl., No. 6, Sec. 1, Jungshing Rd, Wugu Shiang, Taipei County, 248, Taiwan.
authors.forename: Ling-Mei
authors.initials: LM
authors.lastname: Wang
authors.affiliation: STR Genotyping Laboratory, Research and Development Division, Vita Genomics, Inc., 7Fl., No. 6, Sec. 1, Jungshing Rd, Wugu Shiang, Taipei County, 248, Taiwan. lawrence.wu@vitagenomics.com.
authors.forename: Lawrence Shih-Hsin
authors.initials: LS
authors.lastname: Wu
mesh_terms: D000483:Alleles; D044466:Asian People; D019992:Databases as Topic; D018900:Dinucleotide Repeats; D005787:Gene Frequency; D005819:Genetic Markers; D005838:Genotype; D006579:Heterozygote; D006801:Humans; D018895:Microsatellite Repeats; D013624:Taiwan; D044465:White People
chemical_list: D005819:Genetic Markers