[Non-respiratory cyanosis in the newborn].
Four term babies, three boys and one girl, became cyanotic shortly after birth. In two cases the cause was maternal use of drugs: methemoglobinaemia due to use of a chromate and depression of the nervous system due to clomipramine. They recovered. A third child suffered cerebral infarction and was left with decreased left-arm function. The fourth child had a hypoplastic left heart and died. Central cyanosis in a newborn should be cause for concern. A thorough case history should be taken and extensive physical examination carried out. In case of doubt additional diagnostic tests should be performed.
Bolt
R J
RJ
Onze Lieve Vrouwe Gasthuis, afd. Kindergeneeskunde, Amsterdam. roel.bolt@vumc.nl
van Andel
R N
RN
D002544:Cerebral Infarction / Q000150:complications / Q000175:diagnosis; D002840:Chromates / Q000009:adverse effects / Q000627:therapeutic use; D002997:Clomipramine / Q000009:adverse effects / Q000627:therapeutic use; D003490:Cyanosis / Q000139:chemically induced / Q000151:congenital / Q000175:diagnosis* / Q000209:etiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000175:diagnosis; D007231:Infant, Newborn; D008297:Male; D008708:Methemoglobinemia / Q000139:chemically induced / Q000151:congenital / Q000175:diagnosis*
D002840:Chromates; D002997:Clomipramine