title: A new 2-carbamoyl pteridine that inhibits mycobacterial FtsZ.
abstract: The preparation of a new 2-carbamoyl pteridine, its activity data against FtsZ from M. tuberculosis (Mtb), and in vitro antibacterial data against Mtb strain H37Ra are presented.
authors.affiliation: Drug Discovery Division, Southern Research Institute, 2000 Ninth Avenue South, Birmingham, AL 35205, USA. reynolds@sri.org
authors.forename: R C
authors.initials: RC
authors.lastname: Reynolds
authors.forename: S
authors.initials: S
authors.lastname: Srivastava
authors.forename: L J
authors.initials: LJ
authors.lastname: Ross
authors.forename: W J
authors.initials: WJ
authors.lastname: Suling
authors.forename: E L
authors.initials: EL
authors.lastname: White
mesh_terms: D000995:Antitubercular Agents / Q000737:chemistry* / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000037:antagonists & inhibitors* / Q000502:physiology; D003598:Cytoskeletal Proteins / Q000037:antagonists & inhibitors* / Q000502:physiology; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000254:growth & development*; D011621:Pteridines / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000995:Antitubercular Agents; D001426:Bacterial Proteins; D003598:Cytoskeletal Proteins; C071525:FtsZ protein, Bacteria; D011621:Pteridines