Monitoring of selected "non-hepatic" laboratory parameters in hospitalized cirrhotic patients and their influence on prognosis.
OBJECTIVE
To evaluate the prognostic importance of the analysis of leucocytes, prothrombin time and selected serum biochemical parameters in hospitalized patients with liver cirrhosis.


METHODS
At the Intensive Metabolic Care Unit of 1st Department of Internal Medicine we evaluated 150 patients (87 males, 63 females) with liver cirrhosis at average age: 52.51 +/- 7.99 years, Child-Pugh score: 11.34 +/- 2.99. 47 patients have died during hospitalization, 103 patients have improved. Student t-test was used for statistical analysis.


RESULTS
Patients who expired had higher serum leucocyte levels and lower prothrombin time and natriuresis when compared with survivors. Low serum sodium levels, hyperkalemia, decompensated metabolic acidosis, spontaneous hypoglycemia, DIC and renal failure occured more often in the patients with liver cirrhosis who died during hospitalisation.


CONCLUSIONS
Hematological abnmormalities and acid base disturbance are associated with higher hospital mortality rate in patients with liver cirrhosis. (Tab. 6, Ref. 20.)
Jarcuska
P
P
1st Department of Internal Medicine, University Hospital, Kosice, Slovakia. petjarc@yahoo.com
Orolin
M
M
Kovacova
A
A
Hancova
M
M
D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008103:Liver Cirrhosis / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000097:blood; D011379:Prognosis; D011517:Prothrombin Time; D012964:Sodium / Q000097:blood
D015415:Biomarkers; D001786:Blood Glucose; D012964:Sodium; D011188:Potassium