title: [Neurohormonal prediction of post-infarction ventricular dysfunction and coronary disease].
abstract: Little information is available about the potential role of brain (type B) natriuretic peptide in patients with acute myocardial infarction. We therefore analyzed peptide levels, measured at discharge from our coronary care unit, in 56 patients admitted with a diagnosis of acute myocardial infarction. We examined peptide concentrations in the light of different features in our patients, and found a significant association between natriuretic peptide levels and the two most important prognostic factors: left ventricular ejection fraction, and the severity and extent of coronary disease. Type B natriuretic peptide was a good predictor of these features, and we conclude that concentration of type B natriuretic peptide, measured at discharge from the coronary care unit, provides important clinical and prognostic information in patients with acute myocardial infarction.
authors.affiliation: Servicio de Cardiología, Hospital Universitario Infanta Cristina, Badajoz, España. juanmanog@eresmas.com
authors.forename: Juan M
authors.initials: JM
authors.lastname: Nogales
authors.forename: María E
authors.initials: ME
authors.lastname: Fuentes
authors.forename: Angel
authors.initials: A
authors.lastname: Morales
authors.forename: León
authors.initials: L
authors.lastname: Martínez
authors.forename: Domingo
authors.initials: D
authors.lastname: Marzal
authors.forename: Rafael
authors.initials: R
authors.lastname: Alonso
mesh_terms: D003327:Coronary Disease / Q000097:blood / Q000150:complications / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000150:complications / Q000503:physiopathology*; D020097:Natriuretic Peptide, Brain / Q000097:blood / Q000502:physiology; D018377:Neurotransmitter Agents / Q000502:physiology; D012372:ROC Curve; D012044:Regression Analysis; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000503:physiopathology*
chemical_list: D018377:Neurotransmitter Agents; D020097:Natriuretic Peptide, Brain