Non- epidermidis coagulase-negative staphylococcal bacteremia: clinical predictors of true bacteremia.
In order to explore the clinical significance and risk factors for true bacteremia caused by coagulase-negative staphylococci (CNS) other than Staphylococcus epidermidis, a retrospective cohort study of 160 patients with at least one blood culture positive for non- epidermidis CNS was performed. True bacteremia was diagnosed in 32 (20%) of the patients. On multivariate analysis the following factors were associated with true bacteremia: (i) more than one positive blood culture, (ii) presence of a central venous catheter, and (iii) methicillin resistance. The results of this study indicate that non- epidermidis CNS can cause significant bloodstream infections.
Ruhe
J
J
Department of Medicine, Infectious Diseases Section, Tulane University School of Medicine, 1430 Tulane Avenue SL-87, New Orleans, LA 70112, USA.
Menon
A
A
Mushatt
D
D
Dejace
P
P
Hasbun
R
R
D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D016470:Bacteremia / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D003030:Coagulase / Q000378:metabolism*; D015331:Cohort Studies; D016001:Confidence Intervals; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011237:Predictive Value of Tests; D011336:Probability; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D013210:Staphylococcus / Q000145:classification* / Q000201:enzymology; D013212:Staphylococcus epidermidis
D000900:Anti-Bacterial Agents; D003030:Coagulase