title: A population-based risk factor scoring will decrease unnecessary testing for the diagnosis of gestational diabetes mellitus.
abstract: BACKGROUND
  To determine the effectiveness of a population-based risk factor scoring to decrease unnecessary testing for the diagnosis of gestational diabetes mellitus (GDM).
  
  
  METHODS
  We formed a risk factor scoring over five, which questions maternal age, body mass index and first-degree relatives with a diagnosis of diabetes mellitus, a prior macrosomic fetus and adverse outcome during the previous pregnancies. All participants underwent a 50-g glucose challenge test (GCT) followed by a 100-g oral glucose tolerence test (OGTT). We opened the 50-g GCT envelope if the participant had a risk score > or = 1 and opened the 100-g OGTT envelope if the 50-g GCT value was > or = 7.2 mmol/l. After all patients delivered we also built other strategies and tested their detection rates.
  
  
  RESULTS
  Fourteen patients (3.3%) were diagnosed as having gestational diabetes mellitus via a 100-g OGTT. None of the patients with a score of zero had gestational diabetes mellitus. Logistic regression analysis revealed that an increase in the score by one caused a three times increase in gestational diabetes mellitus risk (OR = 3, CI = 1.9-5). Compared with the universal screening, our strategy to screen if the risk score was > or = 1, followed by a 50-g GCT with a 7.2-mmol/l cut-off value, decreased the number of women to be screened by 30% and diagnosed all cases with GDM. Screening the patients with a score > or = 2 would have decreased the number of women to be screened by 63%, still diagnosing 85% of cases with GDM. Also, risk factor-based screening strategies cause a 50% and 53% reduction in the number of OGTT applied, respectively.
  
  
  CONCLUSIONS
  A well integrated, population-based scoring will decrease the number of unnecessary testing but still diagnose 85-100% of GDM cases.
authors.affiliation: SSK Ankara Maternity and Women's Health Teaching Hospital, Etlik, Ankara, Turkey. eray68@hotmail.com
authors.forename: Eray
authors.initials: E
authors.lastname: Caliskan
authors.forename: Fulya
authors.initials: F
authors.lastname: Kayikcioglu
authors.forename: Nilgun
authors.initials: N
authors.lastname: Oztürk
authors.forename: Sevgi
authors.initials: S
authors.lastname: Koc
authors.forename: Ali
authors.initials: A
authors.lastname: Haberal
mesh_terms: D000293:Adolescent; D000328:Adult; D016640:Diabetes, Gestational / Q000453:epidemiology* / Q000209:etiology*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D011159:Population Surveillance / Q000379:methods*; D011237:Predictive Value of Tests; D011247:Pregnancy; D012307:Risk Factors; D012680:Sensitivity and Specificity; D014421:Turkey / Q000453:epidemiology; D019564:Unnecessary Procedures