title: [The correlation between the distant metastases and organ-specific symptoms in the patients with lung cancer].
abstract: In this study, the correlation between distant metastases and metastatic organ-specific abnormalities in patients with lung cancer was evaluated. There were 197 patients who have lung cancer with distant metastases in this study. 141 (71.5%) of them were nonsmall cell lung cancer and 56 (28.5%) of them were small cell lung cancer. While one site of liver, brain and bone metastases were detected in 128 (64.9%) patients, remainders (69 patients, 35.1%) had surrenal, renal, pancreatic, skin, lung, thyroid, abdominal lymph node metastases. Organ-specific symptoms, findings on physical examination and abnormalities in laboratory data were detected in 121 (56.5%), 45 (21%) and 52 (24.2 %) patients, respectively. Sensitivity of predilection of organ-specific symptoms for bone, liver and brain metastases were 67%, 43% and 74% and specificity were 86%, 90% and 76%, respectively. We concluded that organ-specific abnormalities were not so effective to predict metastases in lung cancer. We considered that this result could be due to retrospective analysis and not included enough patients.
authors.affiliation: Atatürk Chest Diseases and Thoracic Surgery Education and Research Hospital, Ankara, Turkey. sibel_alpar@hotmail.com
authors.forename: Sibel
authors.initials: S
authors.lastname: Alpar
authors.forename: Nazire
authors.initials: N
authors.lastname: Uçar
authors.forename: Ayşe
authors.initials: A
authors.lastname: Turgut
authors.forename: Tuba
authors.initials: T
authors.lastname: Kiratli
authors.forename: Berna A
authors.initials: BA
authors.lastname: Dursun
authors.forename: Bahar
authors.initials: B
authors.lastname: Kurt
mesh_terms: D001859:Bone Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000556:secondary; D001932:Brain Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000556:secondary; D002289:Carcinoma, Non-Small-Cell Lung / Q000453:epidemiology* / Q000209:etiology / Q000556:secondary; D018288:Carcinoma, Small Cell / Q000453:epidemiology* / Q000209:etiology / Q000556:secondary; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000556:secondary; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging / Q000379:methods; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014421:Turkey / Q000453:epidemiology