Insect antifeedants from tropical plants: structures of dumnin and dumsenin.
Two novel A-seco limonoids, dumnin and dumsenin, were isolated from the methanolic extract of Croton jatrophoides by bioassay-guided fractionation, and the structures were determined by nuclear magnetic resonance, circular dichroism, and mass spectrometry experiments. These compounds showed potent antifeedant activity (PC(50) <or= 2.0 microg/mL) against the larvae of pink bollworm, Pectinophora gossypiella, and/or fall armyworm, Spodoptera frugiperda, providing results comparable to dumsin and zumsin, previously isolated from the same plant.
Nihei
Ken-Ichi
K
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720-3112, USA.
Asaka
Yukihiro
Y
Mine
Yoshihiro
Y
Ito
Chihiro
C
Furukawa
Hiroshi
H
Ju-Ichi
Motoharu
M
Kubo
Isao
I
D000818:Animals; D002942:Circular Dichroism; D029802:Croton / Q000737:chemistry*; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification; D007814:Larva; D036701:Limonins / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D000432:Methanol; D015394:Molecular Structure; D009036:Moths; D010936:Plant Extracts / Q000737:chemistry; D018411:Spodoptera
D007306:Insecticides; D036701:Limonins; D010936:Plant Extracts; C487582:dumnin; C487583:dumsenin; D000432:Methanol