title: A case study of amnion rupture sequence with acalvaria, blindness, and clefting: clinical and psychological profiles.
abstract: The purpose of this article is to report the case of a 10-year-old girl born with anophthalmia, bilateral oblique facial clefts, and missing scalp and bones over the temporal and parietal areas of the cranial vault bilaterally. Early amnion rupture seems to be the most probable cause of this rare combination of anomalies. Because no similar case has been reported in the literature so far, we describe here the clinical and psychosocial history of this unusual patient, who has been able to live the intellectually and socially normal life of a blind child in spite of the major craniofacial deformities. The already completed and possible future therapeutic strategies are discussed.
authors.affiliation: Cleft Palate and Craniofacial Center, Department of Plastic Surgery, Helsinki University Hospital, Helsinki, Finland. Jyri.Hukki@hus.fi
authors.forename: Jyri
authors.initials: J
authors.lastname: Hukki
authors.forename: Polina
authors.initials: P
authors.lastname: Balan
authors.forename: Rita
authors.initials: R
authors.lastname: Ceponiene
authors.forename: Elina
authors.initials: E
authors.lastname: Kantola-Sorsa
authors.forename: Pia
authors.initials: P
authors.lastname: Saarinen
authors.forename: Heidi
authors.initials: H
authors.lastname: Wikstrom
mesh_terms: D000652:Amniotic Band Syndrome / Q000473:pathology / Q000523:psychology / Q000601:surgery*; D000853:Anophthalmos / Q000523:psychology; D001766:Blindness / Q000523:psychology; D002971:Cleft Lip / Q000523:psychology; D003071:Cognition; D019465:Craniofacial Abnormalities / Q000473:pathology / Q000523:psychology / Q000601:surgery*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D012535:Scalp / Q000601:surgery; D012886:Skull / Q000002:abnormalities / Q000601:surgery; D012917:Social Adjustment