Effect of pravastatin on myocardial perfusion after percutaneous transluminal coronary angioplasty.
We studied the effect of pravastatin on coronary perfusion after percutaneous transluminal coronary angioplasty. An exercise test performed within 2 weeks after percutaneous transluminal coronary angioplasty induced reversible perfusion defects in 66% of patients taking pravastatin and 64% of those taking placebo. At follow-up, the exercise test still induced reversible perfusion defects in 3% of patients taking pravastatin and 29% of those taking placebo.
Manfrini
Olivia
O
Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Policlinico S. Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy.
Pizzi
Carmine
C
Morgagni
GianLuigi
G
Fontana
Fiorella
F
Bugiardini
Raffaele
R
D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000187:drug effects*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000628:therapy*; D005080:Exercise Test; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D017035:Pravastatin / Q000627:therapeutic use*; D011446:Prospective Studies; D016037:Single-Blind Method; D013997:Time Factors; D015899:Tomography, Emission-Computed, Single-Photon
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D017035:Pravastatin