Pentacyclic triterpenoid esters from the fruits of Bruguiera cylindrica.
Six new pentacyclic triterpenoid esters (1-6) together with 3alpha- and 3beta-taraxerol were isolated from the fruits of Bruguiera cylindrica. The structures of the new compounds were characterized as 3alpha-E-feruloyltaraxerol (1), 3alpha-Z-feruloyltaraxerol (2), 3beta-E-feruloyltaraxerol (3), 3beta-Z-feruloyltaraxerol (4), 3alpha-E-coumaroyltaraxerol (5), and 3alpha-Z-coumaroyltaraxerol (6), respectively. Compounds 2 and 6 exhibited weak cytotoxicity against the NCI-H187 cell line.
Laphookhieo
Surat
S
Department of Chemistry, Faculty of Science, Prince of Songkla University, Hat-Yai, Songkhla 90112, Thailand.
Karalai
Chatchanok
C
Ponglimanont
Chanita
C
Chantrapromma
Kan
K
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004952:Esters; D005638:Fruit / Q000737:chemistry; D006801:Humans; D020128:Inhibitory Concentration 50; D007624:KB Cells; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D043982:Rhizophoraceae / Q000737:chemistry*; D013237:Stereoisomerism; D013785:Thailand; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D004952:Esters; D014315:Triterpenes