title: Morbihan's disease: treatment with CO2 laser blepharoplasty.
abstract: Morbihan's disease is a rare condition characterized by chronic persistent erythema and edema of the upper half of the face. Therapeutic regimens such as X-ray irradiation, lymphatic massage, interferon gamma injections, antihistamines, and high-dose antibiotics are often unsatisfactory. Promising results in some patients have been achieved by a systemic combination therapy of isotretinoin with ketotifen or clofazimine. Excision of redundant edematous tissue may be an alternative. We present a 67-year-old Caucasian patient with a two-year history of right lower and upper eyelid swelling and erythema. Systemic therapies with corticocosteroids and antibiotics were not successful, but CO2 laser blepharoplasty led to good cosmetic results with marked improvement of visual impairment and no recurrence during the six-month follow-up period.
authors.affiliation: Department of Dermatology and Allergology, Ruhr-University Bochum, Germany.
authors.forename: Falk Georges
authors.initials: FG
authors.lastname: Bechara
authors.forename: Thomas
authors.initials: T
authors.lastname: Jansen
authors.forename: Rüdiger
authors.initials: R
authors.lastname: Losch
authors.forename: Peter
authors.initials: P
authors.lastname: Altmeyer
authors.forename: Klaus
authors.initials: K
authors.lastname: Hoffmann
mesh_terms: D000368:Aged; D019882:Blepharoplasty; D002245:Carbon Dioxide; D003937:Diagnosis, Differential; D005148:Facial Dermatoses / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D053685:Laser Therapy; D008297:Male; D012393:Rosacea / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*
chemical_list: D002245:Carbon Dioxide