title: Chronic functional constipation in adolescents: clinical findings and motility studies.
abstract: OBJECTIVE
  To evaluate the clinical findings and colonic transit time in adolescents with chronic functional constipation.
  
  
  METHODS
  Forty-eight consecutive adolescents with chronic functional constipation referred to the Gastroenterology Service at the Hospital de Clínicas de Porto Alegre, Brazil were studied. Clinical parameters were assessed using a questionnaire. Total and segmental colonic transit time were measured with radiopaque markers.
  
  
  RESULTS
  Mean age at first visit was 14 +/- 2 years, and age at onset of constipation was 6 +/- 4 years; 90% of patients depended on laxatives, and 86% on intermittent enemas; 76% had a family history of constipation. There was no statistical difference in the amount of daily fiber ingested by patients and controls. Measurements of colonic transit time revealed that 60% of patients had slow transit constipation, 13% had pelvic floor dysfunction, 10% had slow transit constipation associated with pelvic floor dysfunction, and 17% had a normal colonic transit time. Decreased frequency of evacuation and palpable abdominal fecal mass were significantly associated with slow transit constipation.
  
  
  CONCLUSIONS
  Functional constipation in adolescence consists of a heterogeneous group of colonic functional disorders. The identification of these different functional disorders in adolescents will guide specific treatment, which may prevent the progression of this symptom into adult life.
authors.affiliation: Gastroenterology Post Graduate Program, School of Medicine, Universidade Federal do Rio Grande do Sul and the Gastroenterology Service, Hospital de Clínicas de Porto Alegre (HCPA), Ramiro Barcelos 910/1003 Porto Alegre, RS, Brazil. carloszas@brturbo.com
authors.forename: Carlos
authors.initials: C
authors.lastname: Zaslavsky
authors.forename: Sergio Gabriel S
authors.initials: SG
authors.lastname: De Barros
authors.forename: Antonio Carlos
authors.initials: AC
authors.lastname: Gruber
authors.forename: Antonio Carlos
authors.initials: AC
authors.lastname: MacIel
authors.forename: Themis R
authors.initials: TR
authors.lastname: Da Silveira
mesh_terms: D000293:Adolescent; D001938:Brazil; D002648:Child; D002908:Chronic Disease; D003248:Constipation / Q000503:physiopathology*; D005260:Female; D005769:Gastrointestinal Motility; D006801:Humans; D008297:Male