Biotransformation of alpha-isomethylionone to 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)propan-2-one.
The main biodegradation product of (+/-)-alpha-isomethylionone (2) with standard activated sludge was characterized as (+/-)-1-(2,6,6-trimethyl-2-cyclohexen-1-yl)propan-2-one (1) by its analysis and synthesis. Both enantiomers (1a and 1b) of 1 were synthesized by starting from (R)- and (S)-2,4,4-trimethyl-2-cyclohexen-1-ol (3a and 3b), respectively.
Ishizaki
Susumu
S
Technical Research Center, T. Hasegawa Co, Ltd, Kawasaki, Japan.
Itoh
Masamichi
M
Komai
Tsuyoshi
T
Honda
Tsutomu
T
Kitahara
Takeshi
T
D001711:Biotransformation; D003510:Cyclohexanes / Q000737:chemistry* / Q000378:metabolism; D007659:Ketones / Q000737:chemistry* / Q000378:metabolism; D015394:Molecular Structure; D045792:Norisoprenoids / Q000737:chemistry* / Q000378:metabolism*
C494863:1-(2,6,6-trimethyl-2-cyclohexen-1yl)propan-2-one; D003510:Cyclohexanes; D007659:Ketones; D045792:Norisoprenoids; C494862:alpha-isomethylionone