Diastereomer assignment of an olefin-linked bis-paracyclophane by ion mobility mass spectrometry.
trans-1,2-Bis([2.2]paracyclophanyl)ethene (1) exists as a pair of diastereomers whose conformations, and thus effective collision cross sections, are quite different. The two forms can be obtained by different transition metal-catalyzed reactions. To assign meso and racemic structures, a novel method is reported in which experimental gas-phase ion mobility data are compared with theoretical structures obtained from molecular mechanics calculations.
Baker
Erin Shammel
ES
Department of Chemistry and Biochemistry, Center for Polymers and Organic Solids, University of California, Santa Barbara, California 93106, USA.
Hong
Janice W
JW
Gidden
Jennifer
J
Bartholomew
Glenn P
GP
Bazan
Guillermo C
GC
Bowers
Michael T
MT