[Analysis on therapeutic effect of Western and Chinese drug in treating intrahepatic cholestasis pregnancy].
OBJECTIVE
To evaluate the therapeutic effect of Yinchenghao decoction (YCHD) and S-adenosy-L-methionine (SAM) in treating intrahepatic cholestasis of pregnancy (ICP) and improving prognosis of perinatal newborn babies.


METHODS
Sixty in-patients of ICP were randomly divided into two groups, the group A treated with YCHD and the group B treated with SAM. The symptom of itching and serum biochemical indexes, including glycocholic acid, bilirubin and transaminase, were observed after 3 weeks treatment, and the prognosis of perinatal newborn babies between the two groups was compared after delivery.


RESULTS
After treatment, the symptom of itching, serum levels of glycocholic acid, bilirubin and transaminase improved significantly (P < 0.05) in both groups, and the prognosis of newborn in the two groups was similar (P > 0.05).


CONCLUSIONS
Both YCHD and SAM could effectively treat ICP. The former is rather cheaper, so it is more feasible for spreading.
Huang
Jin-yang
JY
Jiangxi Provincial Women and Children Health Hospital, Nanchang 330006. huangjinyang 992@sohu.com
Liu
Huai
H
D000328:Adult; D002780:Cholestasis, Intrahepatic / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008517:Phytotherapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011256:Pregnancy Outcome; D012436:S-Adenosylmethionine / Q000627:therapeutic use*
D004365:Drugs, Chinese Herbal; D012436:S-Adenosylmethionine