[Myocardial infarction and 5,10-methylenetetrahydro-folate reductase mutation].
A 40-year-old woman with previous venous thrombosis in the lower limbs had recurrent myocardial infarction in the early puerperium. The only documented risk factor was an elevated level of plasma homocysteine, associated to a heterozygotic anomaly in the enzyme responsible for its metabolism, 5,10-methylenetetrahydrofolate reductase. The case and approaches to treatment are discussed.
Rodríguez Rodrigo
Francisco J
FJ
Servicio de Cardiología, Hospital Madrid Montepríncipe, Boadilla del Monte, Madrid, Spain. frguezrodigo@hotmail.com
Medina
Juan
J
Velásquez
Eddy
E
Merino
Esther
E
Delcán
Juan L
JL
Guerrero
Jose E
JE
D000328:Adult; D017023:Coronary Angiography; D005838:Genotype; D006710:Homocysteine / Q000097:blood / Q000235:genetics; D006801:Humans; D008297:Male; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics*; D009154:Mutation; D009203:Myocardial Infarction / Q000097:blood / Q000201:enzymology*
D006710:Homocysteine; D042965:Methylenetetrahydrofolate Reductase (NADPH2)