title: [Natural history of obesity].
abstract: Obesity is a chronic disease. At the initial phase, behavioral and environmental factors play a key role in the constitution of adipose tissue excess. Progressively biological alterations of adipose tissue metabolism lead to some degree of irreversibility of the disease and contribute to the development of its metabolic and cardio-vascular complications.
authors.affiliation: Service de Nutrition, Hôtel-Dieu, Université Paris 6, 75181 Paris.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Basdevant
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism*; D002318:Cardiovascular Diseases / Q000209:etiology*; D004777:Environment; D015438:Health Behavior; D006801:Humans; D009765:Obesity / Q000150:complications* / Q000503:physiopathology*