Trypanosoma rangeli Transcriptome Project: Generation and analysis of expressed sequence tags.
Trypanosoma rangeli is an important hemoflagellate parasite of several mammalian species in Central and South America, sharing geographical areas, vectors and reservoirs with T. cruzi, the causative agent of Chagas disease. Thus, the occurrence of single and/or mixed infections, including in humans, must be expected and are of great importance for specific diagnosis and epidemiology. In comparison to several Trypanosomatidae species, the T. rangeli biology and genome are little known, reinforcing the needs of a gene discovery initiative. The T. rangeli transcriptome initiative aims to promote gene discovery through the generation of expressed sequence tags (ESTs) and Orestes (ORF ESTs) from both epimastigote and trypomastigote forms of the parasite, allowing further studies of the parasite biology, taxonomy and phylogeny.
Snoeijer
Cristiane Quimelli
CQ
Departamento de Microbiologia e Parasitologia, Universidade Federal de Santa Catarina, Caixa postal 476, Santa Catarina, Brazil, 88040-900. grisard@ccb.ufsc.br
Picchi
Gisele Fernanda
GF
Dambrós
Bibiana Paula
BP
Steindel
Mário
M
Goldenberg
Samuel
S
Fragoso
Stênio Perdigão
SP
Lorenzini
Daniel Macedo
DM
Grisard
Edmundo Carlos
EC