Lithium amide assisted asymmetric Mannich-type reactions of menthyl acetate with PMP-aldimines.
A lithium enolate of menthyl acetate added to PMP-imines, in the presence of an equimolar amount of lithium diisopropylamide, affords the Mannich-type addition products in high stereoselectivity. [reaction--see text]
Hata
Seiji
S
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.
Iguchi
Mayu
M
Iwasawa
Tetsuo
T
Yamada
Ken-ichi
K
Tomioka
Kiyoshi
K