The importance of screening for sight-threatening retinopathy in incontinentia pigmenti.
Incontinentia pigmenti (IP) is an X-linked dominant disorder of ectodermal structures affecting the skin, hair, teeth, eyes, and central nervous system. The four classic cutaneous stages of the disorder are well known to pediatric dermatologists. However, ocular and neurologic sequelae represent the major morbidity in IP. The two patients reported here highlight some of the potential ocular manifestations of IP and emphasize the importance of early ophthalmologic assessment in this condition.
Wong
Gavin A E
GA
Department of Dermatology, Royal Liverpool Children's Hospital, Liverpool, England. gaewong@hotmail.com
Willoughby
Colin E
CE
Parslew
Richard
R
Kaye
Stephen B
SB
D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006801:Humans; D007184:Incontinentia Pigmenti / Q000150:complications* / Q000175:diagnosis; D008297:Male; D012164:Retinal Diseases / Q000175:diagnosis / Q000209:etiology*; D012867:Skin / Q000473:pathology