title: Reprogramming committed B lineage cells.
abstract: It is generally assumed that once a cell commits to a certain lineage it no longer can change its fate. A new study in this issue of Cell provides compelling evidence that committed mature B lineage cells can be reprogrammed to become macrophages.
authors.affiliation: Divison of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
authors.forename: Cornelis
authors.initials: C
authors.lastname: Murre
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000502:physiology*; D022762:CCAAT-Enhancer-Binding Proteins / Q000502:physiology; D002454:Cell Differentiation / Q000235:genetics / Q000502:physiology*; D005786:Gene Expression Regulation / Q000502:physiology; D006689:Hodgkin Disease / Q000209:etiology; D006801:Humans; D008264:Macrophages / Q000502:physiology
chemical_list: D022762:CCAAT-Enhancer-Binding Proteins