Acute basophilic leukemia with t(8;21).
Acute basophilic leukemia (ABL) is a rare form of leukemia. The diagnostic criteria have recently been described. Morphological evidence for basophilic lineage is required for its classification. However the criteria for remission status and standard therapy is not established. Here we have described an atypical case of ABL and reviewed the literature to high light issues regarding diagnosis and management, which need further discussion.
Seth
Tulika
T
Department of Medical Oncology, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, Ansari Nagar, New Delhi--110029, India. tuliseth@yahoo.com
Vora
Amish
A
Bhutani
Manisha
M
Ganessan
K
K
Jain
Paresh
P
Kochupillai
Vinod
V
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001773:Blood Cells / Q000473:pathology; D001856:Bone Marrow Examination; D002648:Child; D002891:Chromosomes, Human, Pair 21; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D016130:Immunophenotyping; D015471:Leukemia, Basophilic, Acute / Q000145:classification / Q000175:diagnosis* / Q000235:genetics; D012074:Remission Induction; D014178:Translocation, Genetic