title: Laser-induced time-resolved photoacoustic calorimetry study on photo-dissociation of human and bovine oxyhemoglobin.
abstract: The dynamics of the enthalpy and volume changes related to the photo-dissociation of oxygen from human and bovine oxyhemoglobin are investigated by nanosecond time-resolved photoacoustic calorimetry (PAC). The values of enthalpy and volume change associated with the above process are deltaH = 37.8 +/- 3 kcal/mol, deltaV = 5.0 +/- 1 ml/mol for human HbO(2); and deltaH = 35.7 +/- 3.5 kcal/mol, deltaV = 4.8 +/- 1 ml/mol for bovine HbO(2), respectively. A possible explanation for the similar values between both human and bovine oxyhemoglobin is proposed. In addition, the PAC results for human HbO(2) and HbCO are compared and discussed.
authors.affiliation: State Key Laboratory and Institute of Coordination Chemistry, Department of Chemistry, Nanjing University, Nanjing 210093, People's Republic of China.
authors.forename: Hao
authors.initials: H
authors.lastname: Chen
authors.forename: Li
authors.initials: L
authors.lastname: Sun
authors.forename: Gang
authors.initials: G
authors.lastname: Li
authors.forename: Shu Yi
authors.initials: SY
authors.lastname: Zhang
authors.forename: Hui Lan
authors.initials: HL
authors.lastname: Chen
mesh_terms: D000162:Acoustics; D000595:Amino Acid Sequence; D000818:Animals; D002151:Calorimetry; D002263:Carboxyhemoglobin / Q000737:chemistry; D002417:Cattle; D006358:Hot Temperature; D006801:Humans; D007834:Lasers; D008027:Light; D008969:Molecular Sequence Data; D010100:Oxygen / Q000737:chemistry; D010108:Oxyhemoglobins / Q000737:chemistry*; D017386:Sequence Homology, Amino Acid; D013816:Thermodynamics; D013997:Time Factors
chemical_list: D010108:Oxyhemoglobins; D002263:Carboxyhemoglobin; D010100:Oxygen