title: Synthesis and CB1 receptor activities of novel arachidonyl alcohol derivatives.
abstract: Novel derivatives of arachidonyl alcohol were synthesized and evaluated for their CB1 receptor activity by [(35)S]GTP(gamma)S assay using rat cerebellar membranes.
authors.affiliation: Department of Pharmaceutical Chemistry, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland. teija.parkkari@uku.fi
authors.forename: Teija
authors.initials: T
authors.lastname: Parkkari
authors.forename: Juha R
authors.initials: JR
authors.lastname: Savinainen
authors.forename: Anu L
authors.initials: AL
authors.lastname: Rauhala
authors.forename: Tiina L
authors.initials: TL
authors.lastname: Tolonen
authors.forename: Tapio
authors.initials: T
authors.lastname: Nevalainen
authors.forename: Jarmo T
authors.initials: JT
authors.lastname: Laitinen
authors.forename: Jukka
authors.initials: J
authors.lastname: Gynther
authors.forename: Tomi
authors.initials: T
authors.lastname: Järvinen
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000378:metabolism; D000818:Animals; D001095:Arachidonic Acids / Q000138:chemical synthesis* / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D043884:Receptor, Cannabinoid, CB1 / Q000378:metabolism*
chemical_list: D000438:Alcohols; D001095:Arachidonic Acids; D043884:Receptor, Cannabinoid, CB1