title: Study of enteroparasites infection frequency and chemotherapeutic agents used in pediatric patients in a community living in Porto Alegre, RS, Brazil.
abstract: Parasitic infections caused by intestinal protozoan and helminths affect more than two billion people worldwide and chemotherapy is the most commonly used therapeutic procedure. Considering the problems created by parasitic infections and the incorrect use of drugs, the aim of this work was to detect the frequency of enteroparasites infection and to estimate the use of chemotherapeutic agents in children living in the periphery of the city of Porto Alegre, RS, Brazil. Ninety-six preschool age children, who had parasitological exams and who used antiparasitic drugs, were analyzed. The efficacy of treatment was evaluated by stool examination repeated six months after treatment. The same diagnostic test was used to evaluate parasitological cure, which was defined as absence of eggs and cysts in the stool. From these children, 79 (82.3%) were contaminated by some species of parasite, the most prevalent were Ascaris lumbricoides, Trichuris trichiura and Giardia lamblia. The most commonly used drugs were mebendazole (86% of prescriptions) and metronidazole (30.3%). The cure rate in the 79 children, examined 6 months after treatment, was 65.3% for A. lumbricoides and 66.1% for T. trichiura. This study suggests that a continuous education program regarding the prevention and treatment of parasitic infections is an essential tool for their eradication.
authors.affiliation: Faculdade de Farmácia , Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brasil. fmorrone@portoweb.com.br
authors.forename: Fernanda B
authors.initials: FB
authors.lastname: Morrone
authors.forename: Juliana A
authors.initials: JA
authors.lastname: Carneiro
authors.forename: Cristine
authors.initials: C
authors.lastname: dos Reis
authors.forename: Cibele M
authors.initials: CM
authors.lastname: Cardozo
authors.forename: Caroline
authors.initials: C
authors.lastname: Ubal
authors.forename: Geraldo A
authors.initials: GA
authors.lastname: de Carli
mesh_terms: D000977:Antiparasitic Agents / Q000627:therapeutic use*; D001938:Brazil / Q000453:epidemiology; D002675:Child, Preschool; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy* / Q000453:epidemiology* / Q000469:parasitology; D008297:Male; D010270:Parasite Egg Count; D015995:Prevalence; D011446:Prospective Studies
chemical_list: D000977:Antiparasitic Agents