Effect of fluvastatin therapy on coronary flow reserve in patients with hypercholesterolemia.
Coronary flow reserve was evaluated using transthoracic Doppler echocardiography before and after 3 months of fluvastatin therapy in patients with hypercholesterolemia. Coronary flow reserve increased significantly after lipid-lowering therapy, and coronary microcirculation was improved in patients with hypercholesterolemia.
Fujimoto
Kohei
K
Department of Internal Medicine and Cardiology, Osaka City University Medical School, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.
Hozumi
Takeshi
T
Watanabe
Hiroyuki
H
Shimada
Kenei
K
Takeuchi
Masaaki
M
Sakanoue
Yuji
Y
Shimizu
Naruhito
N
Ostuka
Ryo
R
Kawase
Yoshio
Y
Sakamoto
Kazuo
K
Yoshiyama
Minoru
M
Baba
Yuji
Y
Haze
Kazuo
K
Yoshikawa
Junichi
J
D003326:Coronary Circulation / Q000502:physiology*; D015150:Echocardiography, Doppler / Q000379:methods; D005229:Fatty Acids, Monounsaturated / Q000627:therapeutic use*; D005260:Female; D000077340:Fluvastatin; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D006937:Hypercholesterolemia / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D007211:Indoles / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D005229:Fatty Acids, Monounsaturated; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D007211:Indoles; D000077340:Fluvastatin