[Experimental research on the regulating effects of ginseng with hairy antler on the sexual dysfunction rat model induced with adenine].
OBJECTIVE
To research the regulating effects of different dosages of ginseng with hairy antler on the sexual dysfunction model of the gonad and the structure of shenyangxu male rats induced with adenine, and to look for the best compatible proportion of ginseng to hairy antler in the model.


METHODS
Healthy male SD rats, 2 months of age and (220 +/- 20) g in weight, were randomly assigned to 13 groups: normal group, model group, ginseng group, hairy antler group and 9 different proportion groups of ginseng to hairy antler. Observations were made on the exterior syndrome, testosterone in sera, weight index of the prostate and seminal vesicle, and tissue changes of the testis in the experimental rat model.


RESULTS
Dosages of different proportions of ginseng to hairy antler had different improving effects on the exterior syndrome, testosterone in sera, weight index of the prostate and seminal vesicle, and tissue changes of the testis.


CONCLUSIONS
Different proportions of ginseng to hairy antler had different improving effects on the sexual dysfunction model of male rats induced with adenine, and the best compatible proportion of ginseng to hairy antler was 5 to 2, that is, 0.45 g ginseng to 0.18 g hairy antler or 0.90 g ginseng to 0.36 g hairy antler.
Wang
Jiahui
J
Department of Basic Science, Liaoning Traditional Chinese Medical College, Shenyang, Liaoning 110032, China. wjh531@sohu.com
Zhang
Hongmei
H
Fang
Jingkui
J
Chu
Jie
J
D000225:Adenine; D000818:Animals; D000999:Antlers; D004195:Disease Models, Animal; D008297:Male; D008516:Medicine, Chinese Traditional; D005894:Panax; D051381:Rats; D017207:Rats, Sprague-Dawley; D020018:Sexual Dysfunctions, Psychological / Q000139:chemically induced / Q000188:drug therapy*; D013739:Testosterone / Q000097:blood
D013739:Testosterone; D000225:Adenine