title: Buerger's disease with multisystem involvement. A case report and a review of the literature.
abstract: Buerger's disease is a recurrent inflammatory, nonatherosclerotic vasoocclusive disease, which typically affects small and medium-sized arteries, veins, and nerves of the upper and lower extremities. Systemic manifestations involving cerebral, mesenteric, and coronary arteries are exceptional. Moreover, multisystem involvement of 2 or more organs is extremely rare. The authors present a case of Buerger's disease in a patient who subsequently developed cerebral and bowel infarcts as well as cavernomatous transformation of the portal vein. Therefore, Buerger's disease, although rare, does have a chronic aggressive nature in some patients.
authors.affiliation: Department of Rheumatology, Hacettepe University School of Medicine, Ankara, Turkey.
authors.forename: Meral
authors.initials: M
authors.lastname: Calgüneri
authors.forename: M Akif
authors.initials: MA
authors.lastname: Oztürk
authors.forename: Hakan
authors.initials: H
authors.lastname: Ay
authors.forename: Ethem Murat
authors.initials: EM
authors.lastname: Arsava
authors.forename: Deniz
authors.initials: D
authors.lastname: Altinok
authors.forename: Ihsan
authors.initials: I
authors.lastname: Ertenli
authors.forename: Sedat
authors.initials: S
authors.lastname: Kiraz
mesh_terms: D000328:Adult; D005263:Femoral Artery / Q000473:pathology; D006801:Humans; D007238:Infarction / Q000150:complications; D020244:Infarction, Middle Cerebral Artery / Q000150:complications; D007422:Intestines / Q000098:blood supply; D008297:Male; D011169:Portal Vein / Q000473:pathology; D013919:Thromboangiitis Obliterans / Q000175:diagnosis* / Q000473:pathology