Ultrasound prenatal diagnosis of a lateral facial cleft (Tessier number 7).
Lateral facial clefting may occur as an isolated phenomenon or in association with other disorders. It may originate from a failed penetration of ectomesenchyme between the developing maxillary and mandibular prominences, but disruptive factors may also occur in a proportion of cases. The frequency of this abnormality is estimated as 1 in 50 000-175 000 live births. We describe a case of isolated symmetrical lateral facial cleft (number 7 according to the Tessier classification) diagnosed prenatally on ultrasound examination at 26 weeks of gestation.
Presti
F
F
Department of Obstetrics and Gynaecology, University of Genova, Genova, Italy.
Celentano
C
C
Marcazzò
L
L
Dolcetta
G
G
Prefumo
F
F
D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging*; D006801:Humans; D007231:Infant, Newborn; D008265:Macrostomia / Q000000981:diagnostic imaging* / Q000473:pathology; D011247:Pregnancy; D016216:Ultrasonography, Prenatal / Q000379:methods*