[Morphology of tissue reactions around implants after combined surgical repair of the abdominal wall].
Tissue reactions to titanium-nickelide and polypropylen and caprone implants used in surgical treatment of anterior aldomen wall hernias were studied in experiment. Digital density of leukocytes, fibroblasts, vessels, thickness of the capsule were studied. Pronounced inflammatory reaction was observed on day 3 which attenuated on day 14 in case of titanium nickelide and on day 30-60 in case of polypropylene and caprone. Fibroplastic processes start in the first group after 7 days while in the second group only after 30 days of the experiment. Thickness of the capsule around titanium-nickelide was 2-3 times less than around polypropylene and caprone. Thus, titanium-nickelide material is biologically more inert than caprone and polypropylen which are widely used in surgery of hernias.
Vostrikov
O V
OV
Novosibirsk State Medical Academy, 630091, Novosibirsk.
Zotov
V A
VA
Nikitenko
E V
EV
D000818:Animals; D001672:Biocompatible Materials / Q000009:adverse effects*; D002209:Caprolactam / Q000627:therapeutic use; D006555:Hernia, Ventral / Q000601:surgery*; D020007:Implants, Experimental / Q000009:adverse effects*; D007249:Inflammation / Q000150:complications / Q000209:etiology / Q000473:pathology*; D008297:Male; D009532:Nickel / Q000627:therapeutic use; D011126:Polypropylenes / Q000627:therapeutic use; D011183:Postoperative Complications; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D014025:Titanium / Q000627:therapeutic use
D001672:Biocompatible Materials; D011126:Polypropylenes; C040654:titanium nickelide; D002209:Caprolactam; D009532:Nickel; D014025:Titanium