title: [Inadvertent intravenous infusion of 380 mg ropivacaine].
abstract: This is a report about an inadvertent intravenous infusion of 380 mg ropivacaine in a 84-year-old patient over a period of 1.75 h. The level of serum ropivacaine measured immediately after the end of the infusion as well as 2 h and 7 h later, was initially in the lower toxic range (free concentration of 0.48 micro g/ml). The patient showed no symptoms of intoxication neither clinically nor during the technical examinations (EEG, ECG). This case confirms the wide therapeutic range of ropivacaine.
authors.affiliation: Klinik für Anästhesie, Intensivmedizin und Schmerztherapie, Behandlungszentrum Vogtareuth. g.pfeiffer@bhz-vogtareuth.de
authors.forename: G
authors.initials: G
authors.lastname: Pfeiffer
authors.forename: K
authors.initials: K
authors.lastname: Bär
authors.forename: P
authors.initials: P
authors.lastname: Neubauer
authors.forename: M
authors.initials: M
authors.lastname: Höhne
mesh_terms: D000368:Aged; D000577:Amides / Q000008:administration & dosage / Q000009:adverse effects* / Q000097:blood; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000009:adverse effects* / Q000097:blood; D004562:Electrocardiography / Q000187:drug effects; D004569:Electroencephalography / Q000187:drug effects; D005260:Female; D006801:Humans; D019300:Medical Errors; D016343:Monitoring, Intraoperative; D019919:Prosthesis Implantation; D000077212:Ropivacaine
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine