title: Ananosic acids B and C, two new 18(13-->12)-abeo-lanostane triterpenoids from Kadsura ananosma.
abstract: Two new 18(13-->12)-abeo-lanostane triterpenoid acids, ananosic acids B (1) and C (2), were isolated from the stems of Kadsura anaosma. Their structures were elucidated by spectral studies and chemical transformation. Compounds 1 and 2 were evaluated for cytotoxicity using CCRF-CEM leukemia cells and HeLa cells.
authors.affiliation: Department of Chemistry, Yunnan Normal University, Kunming 650092, People's Republic of China.
authors.forename: Ye-Gao
authors.initials: YG
authors.lastname: Chen
authors.forename: Li-Na
authors.initials: LN
authors.lastname: Hai
authors.forename: Xin-Rong
authors.initials: XR
authors.lastname: Liao
authors.forename: Guo-Wei
authors.initials: GW
authors.lastname: Qin
authors.forename: Yu-Yuan
authors.initials: YY
authors.lastname: Xie
authors.forename: Fathi
authors.initials: F
authors.lastname: Halaweish
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D020128:Inhibitory Concentration 50; D032135:Kadsura / Q000737:chemistry*; D007810:Lanosterol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D014315:Triterpenes; C487246:ananosic acid B; C487247:ananosic acid C; D007810:Lanosterol