Arterio-embolic ischemic stroke in children with moyamoya disease.
BACKGROUND
Moyamoya (MM) disease is a rare steno-occlusive cerebrovascular disease known to occur in children and adults. The most serious complications in children are developmental delay and mental retardation due to recurrent hemodynamic stroke.


METHODS
We report two pediatric patients without coagulopathy who suffered from severe arterio-embolic ischemic complications despite antiplatelet medication.


CONCLUSIONS
These observations underline the potential impact of cerebral thromboembolism on the pathophysiology of the stroke and thus on the treatment of children with MM disease.
Horn
Peter
P
Department of Neurosurgery, Universitätsklinikum Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. peter.horn@nch.ma.uni-heidelberg.de
Bueltmann
Eva
E
Buch
Christoph V
CV
Schmiedek
Peter
P
D020771:Anterior Cerebral Artery / Q000473:pathology* / Q000503:physiopathology; D002533:Cerebral Angiography / Q000379:methods; D002648:Child; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D006801:Humans; D008297:Male; D009072:Moyamoya Disease / Q000150:complications* / Q000188:drug therapy / Q000473:pathology*; D020521:Stroke / Q000209:etiology* / Q000473:pathology