[Changes in response latencies of the mouse inferior colliculus neurons depending on the position and movement direction of the spectral contrast].
Variability of response latency of neurons in the mouse inferior colliculus of (Mus musculus) to signals of notch noise and of noise band with regular varying of the notch/band center frequencies, have been studied. Plots of latency and spike count versus notch/band center frequency were constructed (latency functions and spike count functions). Spectral notch/noise band motion crossing boundaries of excitatory areas in the neurons frequency receptive field could produce latency function shifts (and appropriate to this spike count function shifts). Direction-dependent latency function and spike count function shifts were mostly seen for primary-like and V-shape neurons. The most interesting feature of directional sensitivity of inhibitory-dominated neurons was the selective shortening of latency and selective synchronization of the initial spikes (with appropriate to this spike count rise). The dynamic properties of inhibitory-dominated neurons can be explained on the basis of their selective sensitivity to position of spectral contrast in frequency receptive field, connected with disinhibition, and of the character of distribution of excitatory and inhibitory inputs. Manifestation of motion effects was influenced by spectral shape of noise signal and notch width.
Malinina
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I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Acad. Sci., 194223, St. Petersburg, pr. M. Toreza, 44, Russia.
D000161:Acoustic Stimulation; D000200:Action Potentials; D000818:Animals; D007245:Inferior Colliculi / Q000166:cytology / Q000502:physiology*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009474:Neurons / Q000502:physiology*; D011930:Reaction Time