A novel synthesis of functionalized allylsilanes.
A novel facile synthesis of substituted and functionalized allylsilane has been developed. This essentially one-pot procedure involves (1) (dimethylphenylsilyl)methyl cerium chloride addition to cyclopropyl ketone and (2) MgI(2) etherate-mediated Julia homoallylic transposition of the corresponding cyclopropyl carbinol. The bifunctional homoiodo allylsilanes, readily accessible by this method, would be useful and versatile synthons in organic synthesis. [reaction: see text]
Li
Wei-Dong Z
WD
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China. liwd@lzu.edu.cn
Yang
Jin-Hui
JH