title: [Changes of sleep architecture in children with obstructive sleep apnea syndrome].
abstract: OBJECTIVE
  To explore how obstructive sleep apnea syndrome (OSAS) affects children's sleep architecture.
  
  
  METHODS
  Eighty-three children with OSAS were reviewed; every patient was monitored with polysommography for 7 hours at night for 11 parameters, including the number of arousal, snoring index, nadir O(2) desaturation, stage I %, stage II %, show wave sleep (SWS)% and rapid eye movement (REM)%. The basis for diagnosis of OSAS was the widely accepted pediatric diagnostic criteria of apnea/hypopnea index, apnea/ hypopnea index of > 1 episode/hour, nadir O(2) desaturation < 92%. Sleep was scored manually according to the standard set by Rechtschaffen.
  
  
  RESULTS
  In OSAS group, the number of arousal was 22.5 +/- 1.4, snoring index was 70.6 +/- 16.5, and/or SaO(2) was (73.8 +/- 1.9)%. OSAS group had increased stage I : (45.8 +/- 2.0)% vs. (2.3 +/- 1.1)%, t = 22.46, P < 0.01 and decreased stage II : (23.9 = 1.7)% vs (47.9 = 4.4)%, t = - 14.18, P < 0.01, SWS (15.6 +/- 1.8)% vs. (21.1 +/- 5.0)%, t = - 3.123, P < 0.01, REM (14.7 +/- 1.5)% VS. (28.2 +/- 4.1)%, T = -8.923, p < 0.01.
  
  
  CONCLUSIONS
  The severity of OSAS relates to changes of sleep architecture in children. Intermittent nocturnal hypoxia secondary to apnea/hypopnea, and frequent electroencephalogram arousals from sleep may result in significant sleep fragmentation. Children with OSAS had learning problems and failure to thrive.
authors.affiliation: Department of Otorhinolaryngology, Guangzhou Chindren's Hospital, Guangzhou 510120, China.
authors.forename: Da-bo
authors.initials: DB
authors.lastname: Liu
authors.forename: Li-feng
authors.initials: LF
authors.lastname: Zhou
authors.forename: Jian-wen
authors.initials: JW
authors.lastname: Zhong
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D018670:Monitoring, Ambulatory; D017286:Polysomnography; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000145:classification / Q000473:pathology / Q000503:physiopathology*; D012894:Sleep Stages / Q000502:physiology*