title: [A case of large-cell lung cancer with marked leukocytosis successfully treated with chemoradiotherapy].
abstract: A 45-year-old woman was transferred to our hospital for further examination of a persistent fever, marked leukocytosis and abnormal shadow on chest CT scan. At the time of admission, her leukocyte count was 48,800/microliter and her chest CT scan showed a solitary nodule in the right upper lobe with hilar and mediastinal lymphadenopathy. A US-guided biopsy revealed a large-cell carcinoma. She was given radiation (total 60 Gy) and 4 courses of chemotherapy with paclitaxel (150 mg/m2) in combination with carboplatin (AUC = 5). The primary tumor and swollen lymph nodes disappeared and leukocyte count normalized. Although 3 years have passed, no recurrence has been observed.
authors.affiliation: Dept. of Respiratory Medicine, National Maizuru Hospital.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Kubota
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016190:Carboplatin / Q000008:administration & dosage; D018287:Carcinoma, Large Cell / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007964:Leukocytosis / Q000209:etiology*; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage; D013902:Radiography, Thoracic; D012074:Remission Induction; D014057:Tomography, X-Ray Computed
chemical_list: D016190:Carboplatin; D017239:Paclitaxel