title: Lymphocytic hypophysitis with lachrymal, salivary and thyroid gland involvement.
abstract: We report on hypophysitis associated with a prominent lymphoid infiltration of salivary and lachrymal glands in a 35-year-old woman with a dramatic response to steroids. Four years later, overt Graves' disease developed. To our knowledge, pseudotumoral lymphocytic infiltration of both lachrymal and salivary glands has never been described in association with hypophysitis. Benign lymphocytic hypophysitis may belong to a spectrum that extends from low-grade lymphoid proliferation to autoimmune disease. Such a process may follow a regional tissue distribution including pituitary, thyroid, lachrymal and salivary glands.
authors.affiliation: Internal Medicine Unit, Internal Medicine, Bichat Hospital, 46 rue Henri Huchard, 75877 Paris cedex 18, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Lidove
authors.forename: Jean-Charles
authors.initials: JC
authors.lastname: Piette
authors.forename: Frédéric
authors.initials: F
authors.lastname: Charlotte
authors.forename: Nathalie
authors.initials: N
authors.lastname: Cassoux
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Correas
authors.forename: Thomas
authors.initials: T
authors.lastname: Papo