title: Characterization of the ideal candidate for knee radiosynoviorthesis treatment in patients with rheumatoid arthritis.
abstract: OBJECTIVE
  (1). To identify the main parameters that positively influence the outcome of knee radiosynoviorthesis (RSO) in patients with rheumatoid arthritis (RA) and (2). to determine the ideal candidate for this procedure.
  
  
  METHODS
  We considered 80 knees (in 57 patients) that had undergone follow-up for at least 5 years and/or prosthesis implantation after RSO treatment. The parameters evaluated included age, gender, oligo-articular or polyarticular involvement, disease progression, radiological joint damage (Larsen scale), instability and/or axial deviation, body mass index (BMI), and psychological motivation for prosthesis implantation.
  
  
  RESULTS
  Knee Larsen stage IV, presence of instability-axial deviation, disease progression, psychological motivation to the surgical replacement and BMI higher than the 85th percentile were associated with a negative outcome for RSO (prosthesis implantation).
  
  
  CONCLUSIONS
  The ideal candidate for the RSO treatment is a patient with a low Larsen stage, no instability and/or axial deviation and a BMI below the 85th percentile. A patient's psychological motivation for the treatment should be evaluated before the RSO procedure.
authors.affiliation: Dottorato di Ricerca "Radioimmunolocalizzazione dei tumori umani" Università di Torino, Italy.
authors.forename: Ettore
authors.initials: E
authors.lastname: Pelosi
authors.forename: Riccardo
authors.initials: R
authors.lastname: Pellerito
authors.forename: Paolo
authors.initials: P
authors.lastname: Clerico
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Migliaretti
authors.forename: Umberto
authors.initials: U
authors.lastname: Rosso
authors.forename: Gianni
authors.initials: G
authors.lastname: Bisi
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology / Q000532:radiotherapy*; D001294:Attitude to Health; D015992:Body Mass Index; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007558:Italy / Q000453:epidemiology; D007719:Knee Joint / Q000528:radiation effects*; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D011379:Prognosis; D020127:Recovery of Function; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D017678:Sex Distribution; D013583:Synovial Membrane / Q000528:radiation effects*; D016896:Treatment Outcome