title: [Multiple metastases of the penile cancer: an experience of combination chemotherapy].
abstract: A 49-year-old man with penile cancer (cT3N1M0) was referred to our hospital. The pathologic diagnosis was squamous cell carcinoma. The patient underwent penectomy and bilateral inguinal lymphadenectomy without postoperative adjuvant therapy. Six months later, we found multiple metastases of the penile cancer in the lungs. The patient was then treated with combination chemotherapy of cisplatin, methotrexate, bleomycin. However, the tumors were aggressive and did not respond to the therapy. We discuss the use of combination chemotherapy in the case of advanced penile cancer.
authors.affiliation: Department of Urology, Gifu University School of Medicine.
authors.forename: Kosuke
authors.initials: K
authors.lastname: Mizutani
authors.forename: Kensaku
authors.initials: K
authors.lastname: Seike
authors.forename: Takashi
authors.initials: T
authors.lastname: Sugawara
authors.forename: Takako
authors.initials: T
authors.lastname: Masue
authors.forename: Shigeaki
authors.initials: S
authors.lastname: Yokoi
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Ehara
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ishihara
authors.forename: Takashi
authors.initials: T
authors.lastname: Deguchi
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D001859:Bone Neoplasms / Q000556:secondary; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D010412:Penile Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D010413:Penis / Q000601:surgery
chemical_list: D001761:Bleomycin; D002945:Cisplatin; D008727:Methotrexate