title: Antifungal chalcones and new caffeic acid esters from Zuccagnia punctata acting against soybean infecting fungi.
abstract: The crude methanolic extract of Zuccagnia punctata was active toward the fungal pathogens of soybean Phomopsis longicolla and Colletotrichum truncatum. Assay guided fractionation led to the isolation of two chalcones, one flavanone and a new caffeoyl ester derivative as the compounds responsible for the antifungal activity. Another new caffeoyl ester derivative was isolated from the antifungal chloroform extract but proved to be inactive against the soybean infecting fungi up to 50 microg/mL
authors.affiliation: Pharmacognosy, School of Biochemical and Pharmaceutical Sciences, National University of Rosario, Suipacha 531, 2000-Rosario, Argentina.
authors.forename: Laura
authors.initials: L
authors.lastname: Svetaz
authors.forename: Alejandro
authors.initials: A
authors.lastname: Tapia
authors.forename: Silvia N
authors.initials: SN
authors.lastname: López
authors.forename: Ricardo L E
authors.initials: RL
authors.lastname: Furlán
authors.forename: Elisa
authors.initials: E
authors.lastname: Petenatti
authors.forename: Rosanna
authors.initials: R
authors.lastname: Pioli
authors.forename: Guillermo
authors.initials: G
authors.lastname: Schmeda-Hirschmann
authors.forename: Susana A
authors.initials: SA
authors.lastname: Zacchino
mesh_terms: D001203:Ascomycota / Q000187:drug effects*; D002109:Caffeic Acids / Q000302:isolation & purification* / Q000494:pharmacology; D002599:Chalcone / Q000302:isolation & purification* / Q000494:pharmacology; D004952:Esters / Q000302:isolation & purification / Q000494:pharmacology; D007887:Fabaceae / Q000737:chemistry*; D005659:Fungicides, Industrial / Q000302:isolation & purification* / Q000494:pharmacology; D010935:Plant Diseases / Q000382:microbiology; D013025:Glycine max / Q000382:microbiology*
chemical_list: D002109:Caffeic Acids; D004952:Esters; D005659:Fungicides, Industrial; D002599:Chalcone