Magnetic resonance image-reversible findings in a patient with general paresis.
METHODS
We describe clinical, cerebrospinal fluid (CSF), and magnetic resonance imaging (MRI) findings in a patient with general paresis. MRI demonstrated cortical-subcortical atrophy and broad-coalescent high-intensity T2 lesions in right frontotemporal lobes.


RESULTS
After intravenous penicillin therapy, the size of these lesions diminished dramatically. That regression correlated with improvement in neuropsychologic test and CSF analysis.


CONCLUSIONS
To our knowledge, this is the first case reported in the literature of MRI-reversible lesions in a patient with general paresis. We suggest that MRI is of prognostic value in patients with general paresis. Severe atrophy, especially in the temporal lobe, could be a marker of bad clinical outcome.
Berbel-Garcia
Angel
A
Department of Neurology, Hospital Mancha Centro, Alcazar de San Juan (Ciudad Real), Spain. aberbel@yahoo.com
Porta-Etessam
Jesus
J
Martinez-Salio
Antonio
A
Millan-Juncos
Jose Maria
JM
Perez-Martinez
David A
DA
Saiz-Diaz
Rosana A
RA
Toledo-Heras
Maria
M
D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009494:Neurosyphilis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D010406:Penicillins / Q000627:therapeutic use
D010406:Penicillins