title: LF-NMR water self-diffusion and relaxation time measurements of hydrogel contact lenses interacting with artificial tears.
abstract: The different swelling properties of ionic and non-ionic lenses, immersed in sodium chloride or artificial tears, were investigated by Low-Field Nuclear Magnetic Resonance (LF-NMR) through relaxation time and self-diffusion coefficient measurements. A new model was developed to estimate the water self-diffusion coefficient inside the lenses, the results of which revealed a different mechanism of interaction for ionic versus non-ionic materials with artificial tears. The consequence of this finding suggests clinical implications.
authors.affiliation: Dipartimento di Chimica, Università di Roma La Sapienza, Piazzale A. Moro 5, 00185 Rome, Italy. C.Manetti@caspur.it
authors.forename: Cesare
authors.initials: C
authors.lastname: Manetti
authors.forename: Lorena
authors.initials: L
authors.lastname: Casciani
authors.forename: Nicola
authors.initials: N
authors.lastname: Pescosolido
mesh_terms: D003261:Contact Lenses; D004058:Diffusion; D006820:Hyaluronic Acid / Q000737:chemistry; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008422:Materials Testing; D009883:Ophthalmic Solutions; D010100:Oxygen / Q000737:chemistry; D010539:Permeability; D012996:Solutions; D014867:Water
chemical_list: D009883:Ophthalmic Solutions; D012996:Solutions; D014867:Water; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D006820:Hyaluronic Acid; D010100:Oxygen