[Efficacy of an intervention to improve treatment compliance in hyperlipidemias].
OBJECTIVE
To analyse the efficacy of the intervention through a telephone call about patients' compliance with lipaemia therapy.


METHODS
Controlled, randomised clinical trial.


METHODS
Ten clinics at 6 primary care centres.


METHODS
126 people diagnosed with hypercholesterolaemia according to Spanish Consensus criteria were chosen.


METHODS
Two groups were formed. The control group (CG) of 63 patients, who received the doctor's normal treatment; and the Intervention group (IG) of 63 patients, who received in addition a telephone call at 2 weeks, 2 months and 4 months.


METHODS
Pills were counted and cholesterol, triglycerides, HDL-C and LDL-C determined at the start, and at the third and sixth months. Percentages of patients complying (80%-110%), the mean compliance percentage and the degree of control were compared. The reduction of absolute and relative risk (RAR and RRR) and the mean number of people that required an intervention in order to avoid non-compliance (NI) were calculated.


RESULTS
115 people (91.26%) completed the survey, 56 in the IG and 59 in the CG. 77.1% complied with the therapy (CI, 68.4-85.8), (CG=64.4%, CI, 55.3-73.5; IG=93.5%, CI, 88.8-98 [P<.001]). Mean compliance ran at 88.7 +/- 10.2 overall, at 84.4 +/- 12.8 in the CG and at 93 +/- 8.2 in the IG (P<.001). The RAR was 29.1%, the RRR 81%, and the NI was 3.43 patients. The patients controlled ran at 43.9% in the IG (CI, 34.9-52.9) and 23.1% in the CG (CI, 15.4-30.8) (P<.005).


CONCLUSIONS
The telephone intervention is an efficacious way of improving the percentage of patients complying with lipaemia treatment.
Márquez Contreras
E
E
Medicina Familiar y Comunitaria, Centro de Salud la Orden, Avda. Italia 107, 5.o A. 21003 Huelva, Spain. emarquezc@papps.org
Casado Martínez
J J
JJ
Corchado Albalat
Y
Y
Chaves González
R
R
Grandío
A
A
Losada Velasco
C
C
Obando
J
J
de Eugenio
J M
JM
Barrera
J M
JM
D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D013689:Telephone; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D000960:Hypolipidemic Agents; D014280:Triglycerides; D002784:Cholesterol