[Inflammatory colitis and chronic granulomatous disease, a steroid-dependent case report].
Chronic granulomatous disease may lead to inflammatory bowel disease with endoscopic and histological aspects similar to that observed in patients with Crohn's disease. Inflammatory symptoms are generally controlled by steroids, but resistant forms may need total colectomy. Therapeutic strategy in steroid-dependent cases is not yet established. We report here the case of a patient with chronic granulomatous enteritis dependent on steroids at a daily dose of 20 mg. Azathioprine made it possible to withdraw steroid therapy without relapse over twenty Months and without infectious complication during the follow up.
Zanditenas
David
D
Service d'Hépato-Gastroentérologie, Centre Hospitalier Intercommunal de Créteil.
Hagège
Hervé
H
Rosa
Isabelle
I
Cattan
Philippe
P
Ratel-Saby
Sylvie
S
Lons
Thierry
T
Chousterman
Michel
M
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use; D003092:Colitis / Q000188:drug therapy* / Q000209:etiology; D006105:Granulomatous Disease, Chronic / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D012074:Remission Induction / Q000379:methods
D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D001379:Azathioprine