title: Observation of significant signal voids in images of large biological samples at 11.1 T.
abstract: Proton MRI of large biological samples were obtained on an 11.1 T / 40 cm instrument. Images were obtained of a fixed human brain and a large piece of fresh beef. The proton MR images demonstrate severe distortions within these conductive samples, indicative of shortened electrical wavelengths and wave behavior within the sample. These observations have significant implications with respect to the continuing evolution of MR to higher magnetic field strengths on large samples, particularly on humans.
authors.affiliation: The McKnight Brain Institute, University of Florida, Gainesville, Florida, USA.
authors.forename: Barbara L
authors.initials: BL
authors.lastname: Beck
authors.forename: Kelly
authors.initials: K
authors.lastname: Jenkins
authors.forename: Jim
authors.initials: J
authors.lastname: Caserta
authors.forename: Kyle
authors.initials: K
authors.lastname: Padgett
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Fitzsimmons
authors.forename: S J
authors.initials: SJ
authors.lastname: Blackband
mesh_terms: D000818:Animals; D016477:Artifacts; D001921:Brain / Q000033:anatomy & histology; D002417:Cattle; D006801:Humans; D066298:In Vitro Techniques; D008279:Magnetic Resonance Imaging / Q000379:methods; D008460:Meat; D019047:Phantoms, Imaging