title: Splenic marginal zone B-cell lymphoma associated with primary Sjögren's syndrome.
abstract: We describe a 67-year-old woman with primary Sjögren's syndrome who developed a splenic marginal zone B-cell lymphoma, and complained of a dry mouth and Raynaud's phenomenon. She had splenomegaly, swollen lymph nodes and monoclonal IgM-kappa cryoglobulin. After splenectomy, Raynaud's phenomenon had improved with the decrease of cryoglobulin. This is the first case of primary Sjögren's syndrome with splenic marginal zone B-cell lymphoma to be reported.
authors.affiliation: Rheumatic Disease Center, Kurashiki Medical Center, 250 Bakuro-cho, Kurashiki-city, Okayama, Japan. newcity@mtd.biglobe.ne.jp
authors.forename: Susumu
authors.initials: S
authors.lastname: Nishiyama
authors.forename: Shoji
authors.initials: S
authors.lastname: Miyawaki
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications / Q000473:pathology*; D012859:Sjogren's Syndrome / Q000150:complications / Q000473:pathology*; D013160:Splenic Neoplasms / Q000150:complications / Q000473:pathology*