title: Therapy for nerve agent poisoning.
abstract: Neurologists need to familiarize themselves with nerve agents, the most toxic of the chemical warfare agents. Their mode of action lies within the nervous system, and nonneurologists will look to neurologists for expert advice on therapy. These agents cause rapid-onset cholinergic crisis amenable to prompt treatment with specific antidotes. Experience on the battlefield and in terrorist attacks demonstrates that therapy saves lives.
authors.affiliation: Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Newmark
mesh_terms: D000931:Antidotes / Q000627:therapeutic use*; D001285:Atropine / Q000627:therapeutic use; D002619:Chemical Warfare Agents / Q000737:chemistry / Q000506:poisoning*; D006801:Humans; D020258:Neurotoxicity Syndromes / Q000503:physiopathology / Q000628:therapy*; D009498:Neurotoxins / Q000737:chemistry / Q000506:poisoning*; D062025:Organophosphate Poisoning; D010755:Organophosphates / Q000737:chemistry; D009946:Organothiophosphorus Compounds / Q000737:chemistry / Q000506:poisoning; D011220:Pralidoxime Compounds / Q000627:therapeutic use; D011729:Pyridostigmine Bromide / Q000627:therapeutic use; D012524:Sarin / Q000737:chemistry / Q000506:poisoning; D012999:Soman / Q000737:chemistry / Q000506:poisoning
chemical_list: D000931:Antidotes; D001285:Atropine; D002619:Chemical Warfare Agents; D009498:Neurotoxins; D010755:Organophosphates; D009946:Organothiophosphorus Compounds; D011220:Pralidoxime Compounds; D011729:Pyridostigmine Bromide; D012524:Sarin; D012999:Soman; C009680:VX-agent; C028797:pralidoxime; C009374:tabun