[Yield and cytotoxicity of tumor-infiltrating lymphocyte(TIL) following immunochemotherapy]
Tumor-infiltrating lymphocyte (TIL) in the primary site of oral SCC treated with S-PVP of PVP therapy was collected respectively and its yield,that is calculating the amount of TIL per tumor tissue.The cytotoxicity of TIL against the target,Tca8113 was detected.The results showed that the yield of TIL in S-PVP group was three times over that in PVP group.At the ratio of 5 to 1 (effector to target) the cytotoxicity was 38% in S-PVP group and 32% in PVP group.There was no significant difference in its cytotoxicity between two groups.The results revealed that immunochemotherapy of S-PVP regimen for treating oral SCC had neither direct damage to tumor cell from the agents nor antitumor immune reactivity with BRM stimulating an increasing in numbers of TIL.
Hu
Q G
QG
Nanjing Stomatological Hospital. Nanjing 210008, China.
Qiu
W L
WL
Chen
Y B
YB
Bi
Z G
ZG
Ding
X J
XJ