title: Transmit/receive headcoil for optimal 1H MR spectroscopy of the brain in paediatric patients at 3T.
abstract: (1)H magnetic resonance (MR) spectroscopy is a useful tool to obtain metabolic information from the brain in paediatric patients. To detect signals of metabolites at low concentrations or from small volumes, the signal-to-noise ratio (SNR) has to be optimized. The SNR can be increased by going to higher field strengths. However, this leads to higher spectral bandwidths, which increases the chemical shift artefact. Here we present a transmit/receive headcoil which is adapted to the dimensions of the paediatric head and enables PRESS localization with high radio-frequency (RF) bandwidths that minimize the chemical shift displacement to only 5%. In addition, since the pulse lengths are shorter with higher RF bandwidths, the echo time can be reduced to 10 ms improving SNR as well.
authors.affiliation: Department of Radiology (430), University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands. d.klomp@rad.umcn.nl.
authors.forename: D W J
authors.initials: DW
authors.lastname: Klomp
authors.forename: M
authors.initials: M
authors.lastname: van der Graaf
authors.forename: M A A P
authors.initials: MA
authors.lastname: Willemsen
authors.forename: Y M
authors.initials: YM
authors.lastname: van der Meulen
authors.forename: A P M
authors.initials: AP
authors.lastname: Kentgens
authors.forename: A
authors.initials: A
authors.lastname: Heerschap
mesh_terms: D001921:Brain / Q000473:pathology*; D001931:Brain Mapping; D002675:Child, Preschool; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D007223:Infant; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation* / Q000379:methods*