Synaptic proteins and the assembly of synaptic junctions.
Synapses are highly specialized contact sites between neurons and their target cells where information in the form of chemical substances travels from a pre- to a postsynaptic cell. In the central nervous system of mammals, most nerve cells are innervated by functionally distinct types of synapses, each requiring a specific set of molecular constituents for proper function. Various molecular players that may be involved in the assembly of synaptic junctions have been identified recently.
Garner
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University of Alabama, Neurobiology Research Center, Birmingham, AL 35213-0021, USA. garner@nrc.uab.edu
Kindler
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