title: Serum testosterone, growth hormone, and insulin-like growth factor-1 levels, mental reaction time, and maximal aerobic exercise in sedentary and long-term physically trained elderly males.
abstract: The aim of the study was to investigate the effect of regular exercise on maximum oxygen uptake capacity (VO2max), reaction time (RT), testosterone (T), growth hormone (GH), insulin-like growth factor-I (IGF-I) in athletes compared to sedentary controls. VO2max, RT, T, GH, and IGF-I levels were 31.2 +/- 6.2 ml/min/kg, 106.7 +/- 23.2 s, 8.3 +/- 1.3 ng/mL, 1.6 +/- 0.7 ng/mL, 106.5 +/- 27.0 ng/mL in master athlete group and 18.8 +/- 5.1 ml/min/kg, 148.3 +/- 39.3 s, 5.4 +/- 1.7 ng/mL, 0.8 +/- 0.3 ng/mL, 90.2 +/- 23.8 ng/mL in sedentary control group, respectively. The differences between regularly exercising males and the control group of sedentary males were found to be statistically significant. The results showed that long-term exercise decreased RT and increased VO2max, T, and GH in elderly males; elevated serum T and GH levels may be advantageous for brain functions.
authors.affiliation: Celal Bayar University, Faculty of Medicine, Department of Biochemistry, Manisa, Turkey. zekiari@yahoo.com
authors.forename: Zeki
authors.initials: Z
authors.lastname: Ari
authors.forename: Necip
authors.initials: N
authors.lastname: Kutlu
authors.forename: Bekir Sami
authors.initials: BS
authors.lastname: Uyanik
authors.forename: Fatma
authors.initials: F
authors.lastname: Taneli
authors.forename: Gurbuz
authors.initials: G
authors.lastname: Buyukyazi
authors.forename: Talat
authors.initials: T
authors.lastname: Tavli
mesh_terms: D000367:Age Factors; D000368:Aged; D000375:Aging / Q000502:physiology*; D016022:Case-Control Studies; D015444:Exercise / Q000502:physiology*; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D016014:Linear Models; D008297:Male; D008451:Maximal Voluntary Ventilation / Q000502:physiology; D008606:Mental Processes / Q000502:physiology*; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology; D010806:Physical Education and Training / Q000379:methods; D011863:Radioimmunoassay / Q000379:methods; D011930:Reaction Time / Q000502:physiology*; D018709:Statistics, Nonparametric; D013739:Testosterone / Q000097:blood*
chemical_list: D013739:Testosterone; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone