title: Actinomycosis of the temporal bone: a report of a case.
abstract: Actinomycosis is a chronic suppurative infection of the cervicofacial region caused by Actinomyces species, which are anaerobic, gram-positive filamentous bacteria. Although actinomycosis has a propensity for involving the oral cavity, rare cases of actinomycosis involving the temporal bone have been published. We report the case of a 14-year-old girl who presented with clinical, audiometric, and radiologic findings consistent with right chronic suppurative otitis media that persisted despite tympanomastoidectomy. Findings on histologic evaluation of a specimen obtained during revision surgery were consistent with a diagnosis of actinomycosis. Although actinomycosis of the temporal bone is rare, it should be considered in the differential diagnosis of chronic suppurative temporal bone infections that are resistant to standard therapy.
authors.affiliation: Division of Otolaryngology, Department of Surgery, The Children's Hospital of Philadelphia, PA 19104-4399, USA.
authors.forename: Steven E
authors.initials: SE
authors.lastname: Sobol
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Samadi
authors.forename: Ralph F
authors.initials: RF
authors.lastname: Wetmore
mesh_terms: D000196:Actinomycosis / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D000293:Adolescent; D001299:Audiometry; D003937:Diagnosis, Differential; D004432:Ear, Middle / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005260:Female; D006097:Granulation Tissue / Q000473:pathology*; D006314:Hearing Loss, Conductive / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008416:Mastoid / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008417:Mastoiditis / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D010035:Otitis Media, Suppurative / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D013506:Otologic Surgical Procedures / Q000379:methods; D010406:Penicillins / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014432:Tympanic Membrane / Q000601:surgery
chemical_list: D010406:Penicillins