title: Recovery of ambulation after traumatic brain injury.
abstract: OBJECTIVE
  To identify variables that are predictive of independent ambulation after traumatic brain injury (TBI) and to define the time course of recovery.
  
  
  METHODS
  Retrospective review of consecutive admissions of patients with severe TBI over a 32-month period.
  
  
  METHODS
  Brain injury unit in an acute, inpatient rehabilitation hospital.
  
  
  METHODS
  Of 264 patients screened, 116 met criteria that included the ability to participate in motor and functional evaluation on admission to acute rehabilitation, and the absence of other neurologic disorders or fractures that affect one's ability to ambulate.
  
  
  METHODS
  Inpatient rehabilitation on a specialized TBI unit by an interdisciplinary team.Main outcome measures Recovery of independent ambulation and time to recover independent ambulation.
  
  
  RESULTS
  Of eligible patients, 73.3% achieved independent ambulation by latest follow-up (up to 5.1 mo). Patients who achieved independent ambulation were significantly younger (P<.05), had better gait scores on admission (P<.05), and tended to be less severely injured-based on duration of posttraumatic amnesia (PTA; P=.058)-than those who did not ambulate independently. There were no differences in recovery based on neuropathologic profile. Mean time to independent ambulation +/- standard deviation was 5.7+/-4.3 weeks; of those achieving independent ambulation, 82.4% did so by 2 months and 94.1% by 3 months. If not independent by 3 months postinjury, patients had a 13.9% chance of recovery. Multivariate regression analysis generated prediction models for time to independent ambulation, using admission FIM instrument scores and age (38% of variance); initial gait score, loss of consciousness, and age (40% of variance); or initial gait score and PTA (58% of variance), when restricted to just those patients with diffuse axonal injury.
  
  
  CONCLUSIONS
  Most patients with severe TBI achieved independent ambulation; the vast majority did so within 3 months postinjury. Functional measures, injury severity measures, and age can help guide prognosis and expectations for time to recover.
authors.affiliation: HealthSouth Braintree Rehabilitation Hospital, 250 Pond Street, Braintree, MA 02184, USA. dkatz@bu.edu
authors.forename: Douglas I
authors.initials: DI
authors.lastname: Katz
authors.forename: Daniel K
authors.initials: DK
authors.lastname: White
authors.forename: Michael P
authors.initials: MP
authors.lastname: Alexander
authors.forename: Reva B
authors.initials: RB
authors.lastname: Klein
mesh_terms: D000203:Activities of Daily Living; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001930:Brain Injuries / Q000503:physiopathology / Q000534:rehabilitation*; D005260:Female; D020233:Gait Disorders, Neurologic / Q000503:physiopathology / Q000534:rehabilitation; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D015999:Multivariate Analysis; D010348:Patient Care Team; D011237:Predictive Value of Tests; D020127:Recovery of Function / Q000502:physiology*; D012189:Retrospective Studies; D013997:Time Factors