Cystic fibrosis presenting as new onset diabetes mellitus in adolescent twins.
We describe identical adolescent twin girls who presented with symptoms consistent with type 1 diabetes. Medical work up for evaluation of gastrointestinal symptoms led to a diagnosis of cystic fibrosis (CF) in both. These cases suggest that diabetes can be a presenting symptom of CF in the absence of pulmonary symptomatology.
Starkman
Harold
H
The BD Diabetes Center for Children and Adolescents, Children's Medical Center, Atlantic Health System, Morristown, NJ 07962, USA. harold.starkman@ahys.org
Das
Shilpi
S
D000293:Adolescent; D000483:Alleles; D003550:Cystic Fibrosis / Q000150:complications* / Q000175:diagnosis* / Q000235:genetics; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004200:Diseases in Twins / Q000175:diagnosis*; D005260:Female; D006801:Humans; D014430:Twins, Monozygotic
C505032:CFTR protein, human; D019005:Cystic Fibrosis Transmembrane Conductance Regulator