[Adenocarcinoma-associated nonbacterial thrombotic endocarditis as the cause of recurrent strokes].
We describe a 60-year-old female patient without vascular risk factors diagnosed with cardioembolic ischemic stroke due to an atrial septal aneurysm with a right-to-left shunt. However, further investigation after recurrent strokes revealed a nonbacterial thrombotic endocarditis (NBTE) caused by a metastatic adenocarcinoma. The presented case illustrates the difficulties in establishing the diagnosis of NBTE premortally and points out the importance of repeated echocardiographic evaluations of cardiac valves and serological examination of tumor markers in patients with recurrent strokes of unknown origin.
Katchanov
J
J
Klinik für Neurologie, Universitätsmedizin Charité, Berlin. juri.katchanov@charite.de
Doepp
F
F
Borges
A C
AC
Bohner
G
G
Klingebiel
R
R
Ziemer
S
S
Masuhr
F
F
Zschenderlein
R
R
D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis*; D001424:Bacterial Infections; D003937:Diagnosis, Differential; D004696:Endocarditis / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D006338:Heart Neoplasms / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008875:Middle Aged; D012008:Recurrence; D020521:Stroke / Q000175:diagnosis / Q000209:etiology; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology*