title: Relationship between age of menopause and cell-mediated immune hypersensitivity in right- and left-handed women.
abstract: The aim of this work was to study the relationship between age of menopause and cell-mediated immune hypersensitivity in right- (N = 32) and left-handed (N = 15) women who had experienced menopause after age of 34 at least one year before interview. Age of menopause was higher in right-handed than left-handed women. Cell-mediated immunity was higher in left-handers than right-handers. Hand-preference correlated with age of menopause, but inversely correlated with tuberculin reaction and percentages of CD4+ and CD8+ lymphocytes; age of menopause correlated with cell-mediated immunity. The results suggested that early menopause in left-handed women may be due to a more active immune system, especially cell-mediated immunity.
authors.affiliation: Department of Physiology, Medical School, Atatürk University, Erzurum, Turkey. senoldane@hotmail.com
authors.forename: Senol
authors.initials: S
authors.lastname: Dane
authors.forename: Yakup
authors.initials: Y
authors.lastname: Kumtepe
authors.forename: Türkan
authors.initials: T
authors.lastname: Pasinlioglu
authors.forename: Aysenur
authors.initials: A
authors.lastname: Aksoy
mesh_terms: D000328:Adult; D000367:Age Factors; D000375:Aging / Q000502:physiology*; D015496:CD4-Positive T-Lymphocytes / Q000378:metabolism; D018414:CD8-Positive T-Lymphocytes / Q000378:metabolism; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007111:Immunity, Cellular / Q000502:physiology*; D008593:Menopause / Q000276:immunology*; D008875:Middle Aged; D011930:Reaction Time / Q000502:physiology; D014374:Tuberculin Test / Q000379:methods