Birth weight discordance in spontaneous versus induced twins: impact on perinatal outcome.
OBJECTIVE
To compare the rate of birth weight discordance and perinatal outcome of twin pregnancies after assisted reproduction with that of spontaneous twins.


METHODS
A total of 12,920 deliveries were analyzed retrospectively. Seventy-five twin pregnancies after ART were compared to the 94 spontaneous counterparts. Birth weight discordance was defined as a difference of 20% or more.


RESULTS
Discordance rate was elevated (25.3% vs. 17.0%) among ART twins. SGA was increased and NICU admission was more frequent in discordant group. Unlike-sexed twins were more prevalent (73.7% vs. 37.5%) among discordants after ART.


CONCLUSIONS
ART can increase discordance rate which can elevate perinatal risk.
Zádori
J
J
Center for Assisted Reproduction, Kaáli Institute, University of Szeged, Hungary. zjkaali@mail.tiszanet.hu
Kozinszky
Z
Z
Orvos
H
H
Katona
M
M
Kaáli
S G
SG
Pál
A
A
D000328:Adult; D001724:Birth Weight; D000013:Congenital Abnormalities / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007233:Infant, Postmature; D011247:Pregnancy; D015995:Prevalence; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects*; D012189:Retrospective Studies; D012307:Risk Factors; D014427:Twins / Q000502:physiology*