Pentosanpolysulfate (Elmiron) is a potent inhibitor of mast cell histamine secretion.
Chiang
George
G
Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, USA.
Patra
Phani
P
Letourneau
Richard
R
Jeudy
Sheila
S
Boucher
William
W
Green
Marlon
M
Sant
Grannum R
GR
Theoharides
Theoharis C
TC
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology / Q000627:therapeutic use*; D002118:Calcium / Q000378:metabolism; D018856:Cystitis, Interstitial / Q000188:drug therapy*; D004195:Disease Models, Animal; D006633:Histamine Antagonists / Q000494:pharmacology; D006636:Histamine Release / Q000187:drug effects*; D007700:Kinetics; D008297:Male; D008407:Mast Cells / Q000187:drug effects / Q000378:metabolism*; D010426:Pentosan Sulfuric Polyester / Q000494:pharmacology / Q000627:therapeutic use*; D051381:Rats; D017207:Rats, Sprague-Dawley
D000894:Anti-Inflammatory Agents, Non-Steroidal; D006633:Histamine Antagonists; D010426:Pentosan Sulfuric Polyester; D002118:Calcium