title: Morganella morganii causing fatal sepsis in a platelet recipient and also isolated from a donor's stool.
abstract: Bacterial contamination of blood products causes significant patient morbidity and mortality. Contaminated platelet transfusion is a frequent cause of bacteraemia and sepsis because of the storage conditions of platelets. A fatal case of Morganella morganii platelet transfusion associated with sepsis is described, along with procedures traced back to the isolation of M. morganii from a donor's stool. Molecular typing was performed, and the same M. morganii strain was found in blood and post-mortem organ cultures of platelet recipient and platelet bag and in the donor's stool. The route of contamination is unknown. The contamination could be due to either insufficient venipuncture site disinfection or the donor's transient bacteraemia. Patient died 5 days after the transfusion.
authors.affiliation: Department of Transfusion Medicine, Clinical Hospital Centre Zagreb, Zagreb, Croatia. bgolubic@kbc-zagreb.hr
authors.forename: B
authors.initials: B
authors.lastname: Golubić-Cepulić
authors.forename: A
authors.initials: A
authors.lastname: Budimir
authors.forename: V
authors.initials: V
authors.lastname: Plecko
authors.forename: F
authors.initials: F
authors.lastname: Plenković
authors.forename: M
authors.initials: M
authors.lastname: Mrsić
authors.forename: D
authors.initials: D
authors.lastname: Sarlija
authors.forename: T
authors.initials: T
authors.lastname: Vuk
authors.forename: J
authors.initials: J
authors.lastname: Skrlin
authors.forename: S
authors.initials: S
authors.lastname: Kalenić
authors.forename: B
authors.initials: B
authors.lastname: Labar
mesh_terms: D000328:Adult; D015373:Bacterial Typing Techniques; D001782:Blood Donors; D004756:Enterobacteriaceae Infections / Q000175:diagnosis / Q000635:transmission*; D017809:Fatal Outcome; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000628:therapy; D008297:Male; D008875:Middle Aged; D020613:Morganella morganii / Q000302:isolation & purification*; D017713:Platelet Transfusion / Q000009:adverse effects*; D018805:Sepsis / Q000209:etiology / Q000382:microbiology*