title: Angiographic and volumetric intravascular ultrasound comparison between direct sirolimus-eluting stent implantation versus predilation.
abstract: Conventional sirolimus-eluting stent (SES) implantation typically follows balloon predilation. The impact of direct SES implantation on in-stent neointimal hyperplasia and the adjacent reference segments has not been evaluated. The aim of this study was to analyze direct and conventional SES implantation techniques by angiography and serial intravascular ultrasound. Fifty-three patients with single de novo coronary lesions underwent successful conventional (n = 26) and direct (n = 27) SES implantation. At 6-month follow-up, similar in-stent late luminal loss and decreased neointimal hyperplasia volume were seen in the 2 groups, preserving the luminal dimensions at the edges of the stents.
authors.affiliation: Institute Dante Pazzanese of Cardiology, São Paulo, Brazil.
authors.forename: Juan S
authors.initials: JS
authors.lastname: Muñoz
authors.forename: Alexandre
authors.initials: A
authors.lastname: Abizaid
authors.forename: Mariano
authors.initials: M
authors.lastname: Albertal
authors.forename: Gary S
authors.initials: GS
authors.lastname: Mintz
authors.forename: Roselei
authors.initials: R
authors.lastname: Graebin
authors.forename: Fausto
authors.initials: F
authors.lastname: Feres
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Staico
authors.forename: Luiz A
authors.initials: LA
authors.lastname: Mattos
authors.forename: Luiz F
authors.initials: LF
authors.lastname: Tanajura
authors.forename: Andrea S
authors.initials: AS
authors.lastname: Abizaid
authors.forename: Amanda
authors.initials: A
authors.lastname: Sousa
authors.forename: J Eduardo
authors.initials: JE
authors.lastname: Sousa
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D020123:Sirolimus / Q000008:administration & dosage*; D015607:Stents; D017539:Tunica Intima / Q000473:pathology; D018084:Ultrasonography, Interventional
chemical_list: D007166:Immunosuppressive Agents; D020123:Sirolimus