Neuroleptic-induced Tardive Tourette treated with clonazepam: a case report and literature review.
Tardive Tourette syndrome has been reported as a rare complication of neuroleptic treatment. This report describes the first case of neuroleptic-induced tardive Tourette syndrome in the Latin Americas and supports the successful treatment of this disorder with clonazepam. The syndrome developed in a female schizophrenic patient who discontinued medication after 8 years of continuous neuroleptic therapy. Symptoms were unresponsive to increased doses of typical antipsychotics and treatment with an atypical antipsychotic. Significant, sustained improvement occurred with clonazepam. In this report all cases of adult-onset tardive Tourette are reviewed.
Reid
Sandra D
SD
Psychiatry Unit, Department of Clinical Medical Sciences, Faculty of Medical Sciences, University of the West Indies, St. Augustine, Trinidad, West Indies. reid@carib-link.net
D000927:Anticonvulsants / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000009:adverse effects; D002998:Clonazepam / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012196:Review Literature as Topic; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy; D005879:Tourette Syndrome / Q000139:chemically induced / Q000188:drug therapy*
D000927:Anticonvulsants; D014150:Antipsychotic Agents; D002998:Clonazepam