title: Carbohydrate and weight control: where do we stand?
abstract: OBJECTIVE
  The Atkins diet has been criticized and vilified by much of the scientific community since it was proposed 30 years ago, because it challenged nutritional recommendations and dietary guidelines for a healthy diet. However, in spite of such recommendations the prevalence of obesity continues to rise. The present review evaluates recent scientific evidence and attempts to reach consensus on the confusion of weight-reducing diets.
  
  
  RESULTS
  Many dietary macronutrient paradigms have been proposed for the treatment of obesity. Since obesity in its dynamic phase is the result of energy intake exceeding energy expenditure, intuitively to lose weight energy intake should be less than energy expenditure, and one might expect that the macronutrient composition of the diet would have very little, if any, effect. However, short- and long-term therapies with low-carbohydrate or high-protein diets appear to offer advantages over conventional weight-loss regimens for weight loss, body composition and cardiovascular risk factors.
  
  
  CONCLUSIONS
  Low-carbohydrate, Atkins-type diets have been demonstrated to have positive effects on weight loss and biomarkers of cardiovascular risk, which has prompted some researchers to question the validity of present-day dietary guidelines. Although evidence is accumulating in their favour, the safety and efficacy of low-carbohydrate, high-protein diets needs further long-term verification.
authors.affiliation: Nutrition and Health Department, Nestlé Research Center, P.O. Box 44, CH-1000 Lausanne 26, Switzerland. kevin.acheson@rdls.nestle.com
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Acheson
mesh_terms: D001823:Body Composition / Q000187:drug effects; D002318:Cardiovascular Diseases / Q000097:blood / Q000453:epidemiology; D004033:Diet Fads; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D004041:Dietary Fats / Q000008:administration & dosage* / Q000009:adverse effects; D004044:Dietary Proteins / Q000008:administration & dosage* / Q000009:adverse effects; D004734:Energy Metabolism; D038321:Glycemic Index; D006801:Humans; D018673:Nutrition Policy; D009765:Obesity / Q000178:diet therapy* / Q000453:epidemiology / Q000517:prevention & control; D012307:Risk Factors; D012449:Safety; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology
chemical_list: D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins