Ultrasound evaluation of flap thickness, ablation depth, and corneal edema after laser in situ keratomileusis.
OBJECTIVE
The aim of our study was to evaluate the predictability of flap thickness and changes in flap edema over time after laser in situ keratomileusis (LASIK).


METHODS
LASIK was carried out in 30 eyes. The corneal flap was created with a Moria CB manual microkeratome with a flap thickness of 130 microm. Photoablation was performed with the Zeiss-Meditec MEL 70(G-Scan) flying spot excimer laser. Ultrasound pachymetric measurements were performed with the Humphrey Model 855 pachymeter.


RESULTS
Preoperative mean corneal thickness was 568.43 +/- 34.6 microm. After LASIK, mean flap thickness was 133 +/- 26.4 microm. After excimer laser treatment, mean central corneal thickness decreased to a mean 392.4 +/- 37.4 microm. Five minutes after repositioning the flap, mean central corneal thickness was 572.1 +/- 43.4 microm. On the first postoperative day, it decreased to a mean 501.6 +/- 46.6 microm followed by additional decreases: mean 487.4 microm on day 5, 481.8 microm after 1 month, and 479.6 microm at 6 months. The actual photoablation depth was 10 microm less than the predicted depth (paired sample t-test, no statistically significant difference, P = .018). A significant linear correlation was found (Pearson, R =.725, P = .001) between predicted and measured photoablation depth.


CONCLUSIONS
Corneal flap thickness had greater variability than expected. After flap creation, stromal and flap edema occurred, but decreased during the first five postoperative days and stabilized thereafter.
Nagy
Zoltán Z
ZZ
1st Department of Ophthalmology, Semmelweis University, Budapest, Hungary. nz@szem1.sote.hu
Resch
Miklós
M
Süveges
Ildikó
I
D001251:Astigmatism / Q000601:surgery; D015715:Corneal Edema / Q000175:diagnosis* / Q000209:etiology; D003319:Corneal Stroma / Q000000981:diagnostic imaging* / Q000601:surgery; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000601:surgery; D013524:Surgical Flaps; D014463:Ultrasonography