Bilirubin benefits: cellular protection by a biliverdin reductase antioxidant cycle.
Sedlak
Thomas W
TW
Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA. ssnyder@bs.jhmi.edu
Snyder
Solomon H
SH
D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D001663:Bilirubin / Q000097:blood / Q000378:metabolism*; D001664:Biliverdine / Q000378:metabolism*; D005978:Glutathione / Q000378:metabolism; D006801:Humans; D010084:Oxidation-Reduction; D018384:Oxidative Stress / Q000502:physiology; D044925:Oxidoreductases Acting on CH-CH Group Donors / Q000378:metabolism*
D000975:Antioxidants; D044925:Oxidoreductases Acting on CH-CH Group Donors; C019789:biliverdin reductase; D005978:Glutathione; D001664:Biliverdine; D001663:Bilirubin