XIAP protects photoreceptors from n-methyl-n-nitrosourea-induced retinal degeneration.
Petrin
Dino
D
Children's Hospital of Eastern Ontario Research Institute, 401 Smyth Rd., Ottawa, ON, Canada, K1H 8L1. dino@mgcheo.med.uottawa.ca
Baker
Adam
A
Brousseau
Jennifer
J
Coupland
Stuart
S
Liston
Peter
P
Hauswirth
William W
WW
Komeluk
Robert G
RG
Tsilfidis
Catherine
C
D000477:Alkylating Agents / Q000008:administration & dosage; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004596:Electroretinography; D006801:Humans; D008297:Male; D008770:Methylnitrosourea / Q000008:administration & dosage; D020419:Photoreceptor Cells, Vertebrate / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure; D011506:Proteins / Q000378:metabolism / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012162:Retinal Degeneration / Q000139:chemically induced* / Q000517:prevention & control*; D051636:X-Linked Inhibitor of Apoptosis Protein
D000477:Alkylating Agents; D011506:Proteins; D051636:X-Linked Inhibitor of Apoptosis Protein; C496866:XIAP protein, human; D008770:Methylnitrosourea