title: Mass smallpox vaccination and cardiac deaths, New York City, 1947.
abstract: In April 1947, during a smallpox outbreak in New York City (NYC), more than 6 million people were vaccinated. To determine whether vaccination increased cardiac death, we reviewed NYC death certificates for comparable periods in 1946, 1947, and 1948 (N = 81,529) and calculated adjusted relative death rates for the postvaccination period. No increases in cardiac deaths were observed.
authors.affiliation: Division of Epidemiology, New York City Department of Health and Mental Hygiene, New York, New York 10013, USA. lthorpe@health.nyc.gov
authors.forename: Lorna E
authors.initials: LE
authors.lastname: Thorpe
authors.forename: Farzad
authors.initials: F
authors.lastname: Mostashari
authors.forename: Adam M
authors.initials: AM
authors.lastname: Karpati
authors.forename: Steven P
authors.initials: SP
authors.lastname: Schwartz
authors.forename: Susan E
authors.initials: SE
authors.lastname: Manning
authors.forename: Melissa A
authors.initials: MA
authors.lastname: Marx
authors.forename: Thomas R
authors.initials: TR
authors.lastname: Frieden
mesh_terms: D000328:Adult; D003644:Death Certificates / Q000266:history*; D006331:Heart Diseases / Q000209:etiology / Q000266:history* / Q000401:mortality; D049673:History, 20th Century; D006801:Humans; D017589:Immunization Programs / Q000266:history; D032541:Mass Vaccination / Q000266:history*; D008875:Middle Aged; D009519:New York City / Q000453:epidemiology; D012899:Smallpox / Q000517:prevention & control; D012900:Smallpox Vaccine / Q000008:administration & dosage / Q000009:adverse effects / Q000266:history*
chemical_list: D012900:Smallpox Vaccine