title: Chagas seropositive donors in kidney transplantation.
abstract: Among 239 kidney transplantations between September 1992 and September 1997, nine recipients' kidneys were obtained from Chagas seropositive donors. All of these patients were treated with benznidazole (5 mg/kg/d) for 14 days starting on day 0. None of them experienced acute Chagas disease or seroconversion even after 10 years follow-up. We concluded that, due to cadaver shortage, donors with positive serology for Chagas disease should not be excluded.
authors.affiliation: Hospital de Base do Distrito Federal, Brasilia, Brazil. ale.sou@terra.com.br
authors.forename: A A
authors.initials: AA
authors.lastname: Sousa
authors.forename: M C S G
authors.initials: MC
authors.lastname: Lobo
authors.forename: R A
authors.initials: RA
authors.lastname: Barbosa
authors.forename: V
authors.initials: V
authors.lastname: Bello
mesh_terms: D014355:Chagas Disease / Q000517:prevention & control / Q000635:transmission*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney; D016030:Kidney Transplantation / Q000502:physiology*; D008297:Male; D009593:Nitroimidazoles / Q000627:therapeutic use*; D013997:Time Factors; D014019:Tissue Donors; D014344:Trypanocidal Agents / Q000627:therapeutic use*
chemical_list: D009593:Nitroimidazoles; D014344:Trypanocidal Agents; C009999:benzonidazole