[Nuchal translucency measurement--non invasive ultrasound screening for fetal abnormalities. Part I].
OBJECTIVE
Fetal abnormalities are the most common cause of perinatal and postnatal death and infant handicap. In the last years came into being many diagnostic methods making possible--precise and accurate diagnosis of fetal malformation.


METHODS
Estimation the value of the screening test for fetal abnormalities based on the nuchal translucency measurement between 10-14th week of pregnancy.


METHODS
A group of 675 women with singleton pregnancies undergoing first trimester nuchal translucency measurement. Nuchal translucency thickness was measured by transvaginal ultrasound examination according to Nicolaides. Derived risks were then calculated.


RESULTS
When we used a risk of 1:250 as the cutoff to define a positive result on the screening test, the rate of detection of fetal abnormalities was 100%, with a false positive rate of 1.3%.


CONCLUSIONS
First trimester nuchal translucency measurement is an effective method of screening for fetal abnormalities (obstetrical high-risk group).
Baś-Budecka
Elzbieta
E
Instytut Ginekologii i Połoznictwa UM w łodzi.
Suzin
Jacek
J
Lipecka-Kidawska
Elzbieta
E
Sieroszewski
Piotr
P
D000328:Adult; D025063:Chromosome Disorders / Q000000981:diagnostic imaging; D000013:Congenital Abnormalities / Q000000981:diagnostic imaging* / Q000196:embryology / Q000517:prevention & control; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D009333:Neck / Q000000981:diagnostic imaging / Q000196:embryology; D011237:Predictive Value of Tests; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D018566:Pregnancy, High-Risk; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal / Q000379:methods