title: Incidence of acute angle-closure glaucoma in Dalmatia, southern Croatia.
abstract: OBJECTIVE
  To investigate the incidence of acute angle-closure glaucoma among residents of Dalmatia, southern part of Croatia.
  
  
  METHODS
  We reviewed hospital records of 176 patients with acute angle-closure glaucoma treated between January 1995 and December 2001 at the Departments of Ophthalmology at four hospitals in Dalmatia. There were 122 women, aged between 29 and 89 years (median age; 68 years), and 54 men, aged between 33 and 88 years (median age, 70 years).
  
  
  RESULTS
  The unadjusted crude incidence was 2.9/100,000 (95% confidence interval [CI], 1.6-4.5). The unadjusted crude incidence among men and women was 1.9 (95% CI, 0.3-3.8) and 3.9 (95% CI, 1.7-6.1) cases/100,000 per year, respectively. The relative risk (RR) of developing acute angle-closure glaucoma was 2.1 (95% CI, 1.5-2.9) times higher for women as compared to men. The RR of acute angle-closure glaucoma was 1.9 (95% CI, 0.6-6.2) in the 40-49 years group, 6.5 (95% CI, 2.3-18.8) in the 50-59 years group, 17 (95% CI, 6.3-47.8) in the 60-69 years group, and 28 (95% CI, 10.4-77.3) in the over 69 years group. The median time from the onset of symptoms to presentation at the hospital was 2 days (range, 1-15 days). In 87 (48%) patients intraocular pressure control was achieved by medical treatment, 41 (23%) patients underwent peripheral iridectomy, and 48 (27%) patients required a trabeculectomy. In 35 (73%) out of 48 patients managed by filtering surgery, the delay in treatment was 3 or more days. In 34 (19%) eyes with final visual acuity 0.1 or worse, the delay in presentation was 3 days or more. No statistically significant association was found between acute angle-closure glaucoma and seasonal variation (chi-square=0.85; p=0.8).
  
  
  CONCLUSIONS
  Earlier recognition of the patients with acute angle-closure glaucoma and a shorter time of delay in presentation could have saved many patients from surgery and vision loss each decade.
authors.affiliation: Eye Clinic, Split University Hospital Center, Spincićeva 1, 21000 Split, Croatia. lovreb@kbsplit.hr
authors.forename: Lovro
authors.initials: L
authors.lastname: Bojić
authors.forename: Zdravko
authors.initials: Z
authors.lastname: Mandić
authors.forename: Milan
authors.initials: M
authors.lastname: Ivanisević
authors.forename: Kajo
authors.initials: K
authors.lastname: Bucan
authors.forename: Suzana
authors.initials: S
authors.lastname: Kovacević
authors.forename: Antonela
authors.initials: A
authors.lastname: Gverović
authors.forename: Alenka
authors.initials: A
authors.lastname: Miletić-Jurić
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017523:Croatia / Q000453:epidemiology; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000453:epidemiology* / Q000628:therapy; D006748:Hospital Departments / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009885:Ophthalmology / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012307:Risk Factors; D012621:Seasons