title: [Detection of TCR-gamma chain gene rearrangement in malignant histiocytosis].
abstract: OBJECTIVE
  To investigate the lineage of the malignant cells in malignant histiocytosis.
  
  
  METHODS
  Polymerase chain reaction with two groups of common primers for TCR-gamma gene was used to analyze the malignant cells of 28 autopsied cases of malignant histiocytosis.
  
  
  RESULTS
  Monoclonal TCR-gamma gene rearrangements were detected in 12 out of the 28 samples (43%).
  
  
  CONCLUSIONS
  Most cases diagnosed as malignant histiocytosis in Southwest China seems to be peripheral T-cell lymphomas.
authors.affiliation: Department of Pathology, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Chang-li
authors.initials: CL
authors.lastname: Lu
authors.forename: Gan-di
authors.initials: GD
authors.lastname: Li
authors.forename: Wei-ping
authors.initials: WP
authors.lastname: Liu
authors.forename: Jia
authors.initials: J
authors.lastname: Guo
authors.forename: Feng-yuan
authors.initials: FY
authors.lastname: Li
authors.forename: Dian-ying
authors.initials: DY
authors.lastname: Liao
authors.forename: Wen-yan
authors.initials: WY
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019002:CD56 Antigen / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D005260:Female; D015334:Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; D015614:Histiocytosis / Q000235:genetics* / Q000276:immunology; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction
chemical_list: D019002:CD56 Antigen