title: New ring-expansion reactions of hydroxy propenoyl cyclic compounds under palladium(0)/phosphine-catalyzed conditions.
abstract: [reaction: see text] Palladium(0)-catalyzed one-atom ring-expansion of 1-hydroxy-2,2-dialkyl-1-propenoylindan derivatives has been achieved in the presence of P(o-tolyl)(3) giving 2-hydroxy-3,3-dialkyl-2-vinyl-1-tetralone derivatives in excellent yields. This ring-expansion reaction was applied to a 17-(1-oxo-2-propenyl)-beta-estradiol derivative and furnished a similar ring-expanded product in an excellent yield.
authors.affiliation: Faculty of Pharmaceutical Sciences, The University of Tokushima, Sho-machi, Tokushima 770-8505, Japan. ynagao@ph.tokushima.ac.jp
authors.forename: Yoshimitsu
authors.initials: Y
authors.lastname: Nagao
authors.forename: Satoru
authors.initials: S
authors.lastname: Tanaka
authors.forename: Akiharu
authors.initials: A
authors.lastname: Ueki
authors.forename: Masunori
authors.initials: M
authors.lastname: Kumazawa
authors.forename: Satoru
authors.initials: S
authors.lastname: Goto
authors.forename: Takashi
authors.initials: T
authors.lastname: Ooi
authors.forename: Shigeki
authors.initials: S
authors.lastname: Sano
authors.forename: Motoo
authors.initials: M
authors.lastname: Shiro