title: Ultracompact biochemical sensor built with two-dimensional photonic crystal microcavity.
abstract: We report an experimental demonstration of an ultracompact biochemical sensor based on a two-dimensional photonic crystal microcavity. The microcavity, fabricated on a silicon-on-insulator substrate, is designed to have a resonant wavelength (lambda) near 1.5 microm. The transmission spectrum of the sensor is measured with different ambient refractive indices ranging from n = 1.0 to n = 1.5. From observation of the shift in resonant wavelength, a change in ambient refractive index of delta(n) = 0.002 is readily apparent. The correspondence between absolute refractive index and resonant wavelength agrees with numerical calculation to within 4% accuracy. The evaporation of water in a 5% glycerol mixture is also used to demonstrate the capability for in situ time-resolved sensing.
authors.affiliation: Agilent Technologies, Inc., 3500 Deer Creek Road, Polo Alto, California 94304, USA. edmond_chow@agilent.com
authors.forename: E
authors.initials: E
authors.lastname: Chow
authors.forename: A
authors.initials: A
authors.lastname: Grot
authors.forename: L W
authors.initials: LW
authors.lastname: Mirkarimi
authors.forename: M
authors.initials: M
authors.lastname: Sigalas
authors.forename: G
authors.initials: G
authors.lastname: Girolami
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods; D008904:Miniaturization; D015336:Molecular Probe Techniques / Q000295:instrumentation*; D055095:Optics and Photonics / Q000295:instrumentation; D017785:Photons; D025941:Protein Interaction Mapping / Q000295:instrumentation / Q000379:methods; D012031:Refractometry / Q000295:instrumentation* / Q000379:methods; D013057:Spectrum Analysis / Q000295:instrumentation* / Q000379:methods; D014159:Transducers