title: [Giant leiomyoma of the ovary].
abstract: Most of benign and malignant mesenchimal tumors may develop in the ovary. A case of 58 years old female, operated for ovary tumor is presented. A large soft mase 10-7-5 cm with in semilucent capsule is resected. Different (small and large) nodules with in edematous stroma constitute the tumor and imitate a large ovarian cancer. After histologic examination the nodules are composed of criss-crossing and whirling bundles of smooth muscle cells. Immunohistochemically they express Desmin diffusely and don't express Vimentin and S100 protein. Smooth muscle cells bundles in large amount of edematous, colagenous stroma look like islands. Stromal cells are Vimentin positive. Operation in this case is just limited to the tumor.
authors.affiliation: Department of Pathology, Department of Oncogynecology Medical Institute, Pleven.
authors.forename: I
authors.initials: I
authors.lastname: Brŭchkova
authors.forename: G
authors.initials: G
authors.lastname: Gorchev
mesh_terms: D003893:Desmin / Q000096:biosynthesis; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007889:Leiomyoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D018613:Microscopy, Confocal; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D009418:S100 Proteins / Q000096:biosynthesis; D014746:Vimentin / Q000096:biosynthesis
chemical_list: D003893:Desmin; D009418:S100 Proteins; D014746:Vimentin