Influence of 50 Hz frequency sinusoidal magnetic field on the blood-brain barrier permeability of diabetic rats.
The combined effects of diabetes and a 50 Hz, 5 mT RMS flux density sinusoidal magnetic field for 8 h a day, for 21 consecutive days on the permeation of Evans-blue dye through the blood-brain barrier were studied in male Wistar albino rats. Our results suggest that magnetic field has no effect on the blood-brain barrier permeability in normoglycemic animals, but that diabetic rats are vulnerable to magnetic fields.
Oztaş
Baria
B
Istanbul University, Istanbul Faculty of Medicine, Department of Physiology, Capa, Istanbul, Turkey. bariaoztas@hotmail.com
Kalkan
Tunaya
T
Tuncel
Handan
H
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001812:Blood-Brain Barrier / Q000528:radiation effects*; D001921:Brain / Q000378:metabolism / Q000473:pathology; D002531:Cerebellum / Q000378:metabolism / Q000473:pathology; D004396:Coloring Agents; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000378:metabolism*; D004574:Electromagnetic Fields; D005070:Evans Blue; D008279:Magnetic Resonance Imaging / Q000295:instrumentation; D008280:Magnetics; D008297:Male; D010539:Permeability; D051381:Rats; D017208:Rats, Wistar; D013311:Streptozocin
D001786:Blood Glucose; D004396:Coloring Agents; D005070:Evans Blue; D013311:Streptozocin