title: Using pharmacogenetics to improve drug safety and efficacy.
authors.affiliation: The Center for the Advancement of Genomics, Rockville, Md, USA.
authors.forename: Susanne B
authors.initials: SB
authors.lastname: Haga
authors.forename: Wylie
authors.initials: W
authors.lastname: Burke
mesh_terms: D000963:Antimetabolites / Q000009:adverse effects; D035843:Biomedical Research; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D006903:Hydroxymethylglutaryl CoA Reductases / Q000235:genetics; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D015122:Mercaptopurine / Q000009:adverse effects; D008780:Methyltransferases / Q000235:genetics; D004364:Pharmaceutical Preparations / Q000378:metabolism; D010597:Pharmacogenetics; D013866:Thioguanine / Q000009:adverse effects
chemical_list: D000963:Antimetabolites; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D004364:Pharmaceutical Preparations; D015122:Mercaptopurine; D006903:Hydroxymethylglutaryl CoA Reductases; D008780:Methyltransferases; C022745:thiopurine methyltransferase; D013866:Thioguanine