title: Granulocytic sarcoma: an atypical presentation in the oral cavity.
abstract: Acute myelogenous leukemia (AML) is a hematologic disorder that is characterized by an abnormal proliferation of immature myeloid cells. Granulocytic sarcomas are clusters of leukemic myeloid cells that may develop as a result of AML. Oral manifestations of AML are common and often involve enlargements of the gingiva and/or mucosal tissue from direct leukemia cell infiltration. We describe the case history of a 50-year-old man who had an ulcerative lesion of the oral mucosa that was determined to be a granulocytic sarcoma of AML-MO subtype. The combination of both the subtype and clinical presentation of the leukemia makes this presentation unusual, and to the best of our knowledge, of a type that has not been previously reported in the literature.
authors.affiliation: University of Pennsylvania School of Dental Medicine, USA. ets@pobox.upenn.edu
authors.forename: Eric T
authors.initials: ET
authors.lastname: Stoopler
authors.forename: Andres
authors.initials: A
authors.lastname: Pinto
authors.forename: Faizan
authors.initials: F
authors.lastname: Alawi
authors.forename: Sree
authors.initials: S
authors.lastname: Raghavendra
authors.forename: Ricardo
authors.initials: R
authors.lastname: Boyce
authors.forename: David
authors.initials: D
authors.lastname: Porter
authors.forename: Thomas P
authors.initials: TP
authors.lastname: Sollecito
mesh_terms: D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D007951:Leukemia, Myeloid / Q000473:pathology*; D015470:Leukemia, Myeloid, Acute / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology*; D019226:Oral Ulcer / Q000473:pathology*