title: Tuning porphyrin/DNA supramolecular assemblies by competitive binding.
abstract: Addition of an intercalating but nonaggregating porphyrin, AuT4, to a preformed adduct between DNA and a strongly aggregating porphyrin, t-H2Pagg, permits control of the extent of aggregation of the latter. The size and the intensity of the ICD and RLS signals depend linearly on the concentration of the intercalating dye and decrease markedly on increasing the concentration of the available binding sites on the biopolymer template.
authors.affiliation: Dipartimento di Chimica Inorganica, Chimica Analitica e Chimica Fisica, Università di Messina, Salita Sperone 31, 98166 Vill.S.Agata, Messina, Italy.
authors.forename: Luigi Monsù
authors.initials: LM
authors.lastname: Scolaro
authors.forename: Andrea
authors.initials: A
authors.lastname: Romeo
authors.forename: Robert F
authors.initials: RF
authors.lastname: Pasternack
mesh_terms: D001667:Binding, Competitive; D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry* / Q000378:metabolism*; D015394:Molecular Structure; D011166:Porphyrins / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D011166:Porphyrins; D004247:DNA