Accuracy of thin-slice computed tomography in the detection of coronary stenoses.
OBJECTIVE
Our aim was to investigate the accuracy of multislice spiral computed tomography (MSCT) in the detection of significant (>50%) coronary stenosis using a scanner equipped for 16 x 0.625 mm collimation.


METHODS
In 64 patients (59 male, mean age 58 +/- 5 years) with suspected coronary artery disease, MSCT (GE Light Speed-16, collimation: 16 x 0.625 mm) was performed 20 +/- 5 days before coronary angiography (CAG). Only angiographic segments >1.5 mm were considered for analysis.


RESULTS
In all patients, MSCT was carried out without complications. Three patients were excluded from the analysis. Of 729 angiographic segments, 613 (84%) were judged evaluable by MSCT. Considering only the segments judged evaluable, the sensitivity was 89%, specificity 98%, positive predictive value 90%, and negative predictive value 98%. Including all segments in the analysis (evaluable and nonevaluable), sensitivity was 78%.


CONCLUSIONS
Using a scanner with a collimation of 16 x 0.625 mm, our study confirms the potential role of MSCT in the detection of significant coronary stenosis with a sensitivity of 89% and a very high specificity (98%). Exclusion criteria and less than full evaluability of the coronary arteries must still be considered limitations of the method.
Martuscelli
Eugenio
E
Department of Internal Medicine, Division of Cardiology, University of Rome "Tor Vergata", Viale Oxford 81, 00133 Rome, Italy. e.martuscelli@libero.it
Romagnoli
Andrea
A
D'Eliseo
Alessia
A
Razzini
Cinzia
C
Tomassini
Marco
M
Sperandio
Massimiliano
M
Simonetti
Giovanni
G
Romeo
Francesco
F
D023921:Coronary Stenosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000592:standards*