title: CD45RA+ and CD45RO+ lymphocyte subpopulations in patients with monoclonal gammopathies: correlations with diagnosis, clinical stage and treatment status.
abstract: Alterations in blood lymphocyte subsets may be involved in the development of overt myeloma. Naive (CD4+CD45RA+) and memory (CD4+CD45RO+) helper T-cell subsets are important effectors of immune T-cell regulation. We analyzed the distribution of these blood lymphocyte subpopulations in patients with monoclonal gammopathies, considering the type of disorder, clinical stage, and treatment status.
authors.forename: José María
authors.initials: JM
authors.lastname: Raya Sánchez
authors.forename: Luis Hernández
authors.initials: LH
authors.lastname: Nieto
authors.forename: María Luisa
authors.initials: ML
authors.lastname: Brito Barroso
authors.forename: Gloria
authors.initials: G
authors.lastname: González Brito
authors.forename: María
authors.initials: M
authors.lastname: del Mar Caballero Gómez
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D017493:Leukocyte Common Antigens / Q000032:analysis*; D016131:Lymphocyte Subsets / Q000473:pathology*; D008297:Male; D010265:Paraproteinemias / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy
chemical_list: D017493:Leukocyte Common Antigens