Plant "polyphenolic" small molecules can induce a calorie restriction-mimetic life-span extension by activating sirtuins: will "polyphenols" someday be used as chemotherapeutic drugs in Western medicine?
Quideau
Stéphane
S
Institut Européen de Chimie et Biologie, 2 rue Robert Escarpit, 33607 Pessac, France. s.quideau@iecb.u-bordeaux.fr
D000818:Animals; D031204:Caloric Restriction; D005419:Flavonoids / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use*; D006801:Humans; D008136:Longevity / Q000187:drug effects* / Q000502:physiology; D010636:Phenols / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use*; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use*; D059808:Polyphenols; D037761:Sirtuins / Q000378:metabolism*
D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts; D059808:Polyphenols; D037761:Sirtuins