Expression profiling: fishing and chips.
Expression profiling approaches are potentially valuable in helping to define novel gene products which may be important in disease pathogenesis or treatment response. However, there are many pitfalls which need to be considered in the design of experiments of this kind and in considering interpretation of data from such studies. Some of these are discussed.
Hall
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Division of Therapeutics and Molecular Medicine, D Floor, South Block, Queen's Medical Centre, Nottingham NG7 2UH, UK. ian.hall@nottingham.ac.uk
D002446:Celiac Disease / Q000235:genetics*; D020869:Gene Expression Profiling / Q000379:methods*; D006801:Humans; D012107:Research Design