title: [Multiple cerebral white matter lesions following head trauma with eyeball contusion].
abstract: We reported a 36-year-old man with multiple cerebral white matter lesions following head trauma with eyeball contusion. He had suffered from optic neuritis on non-injured side after one and half months from the head trauma. Brain MRI revealed multiple cerebral white matter lesions and lumbar puncture disclosed an elevated level of protein of the cerebrospinal fluid after two and half months from the head trauma. He was treated with steroid pulse therapy and resulted in an improvement of his visual acuity and a remarkable decrease of multiple cerebral white matter lesions. There has been a controversy concerning the causal relationship between trauma and multiple sclerosis (MS). In this case, MS-like multiple cerebral white matter lesions are considered to be relevant to the head trauma.
authors.affiliation: Department of Neurology, Neurological Institute, Tokyo Women's Medical University School of Medicine.
authors.forename: Tomomi
authors.initials: T
authors.lastname: Nakamura
authors.forename: Kohei
authors.initials: K
authors.lastname: Ota
authors.forename: Naoki
authors.initials: N
authors.lastname: Niwa
authors.forename: Megumi
authors.initials: M
authors.lastname: Takeuchi
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Uchiyama
authors.forename: Makoto
authors.initials: M
authors.lastname: Iwata
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D003288:Contusions / Q000150:complications; D006259:Craniocerebral Trauma / Q000150:complications* / Q000473:pathology; D015807:Eye Injuries, Penetrating / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000209:etiology; D009902:Optic Neuritis / Q000209:etiology