Ribosome function: governing the fate of a nascent polypeptide.
Recent data highlight how eukaryotic ribosomes connect polypeptide synthesis to translational regulation and targeting. Information contained in nascent polypeptides can be transmitted by surprisingly diverse routes.
Rospert
Sabine
S
Institut fur Biochemie und Molekularbiologie, Universität Freiburg, Hermann-Herder-Strasse 7, D-79104 Freiburg, Germany. sabine.rospert@biochemie.uni-freiburg.de
D008958:Models, Molecular; D018716:Molecular Mimicry / Q000235:genetics / Q000502:physiology; D010455:Peptides / Q000235:genetics* / Q000502:physiology; D010458:Peptidyl Transferases / Q000235:genetics / Q000502:physiology*; D014176:Protein Biosynthesis / Q000235:genetics / Q000502:physiology; D017434:Protein Structure, Tertiary; D012270:Ribosomes / Q000235:genetics* / Q000502:physiology*; D018271:Signal Recognition Particle / Q000235:genetics / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology
D010455:Peptides; D018271:Signal Recognition Particle; D010458:Peptidyl Transferases