Pathophysiology of peripheral nerve injury: a brief review.
Clinicians caring for patients with brachial plexus and other nerve injuries must possess a clear understanding of the peripheral nervous system's response to trauma. In this article, the authors briefly review peripheral nerve injury (PNI) types, discuss the common injury classification schemes, and describe the dynamic processes of degeneration and reinnervation that characterize the PNI response.
Burnett
Mark G
MG
Department of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. burnettmg@hotmail.com
Zager
Eric L
EL
D001369:Axons / Q000473:pathology; D006801:Humans; D007511:Ischemia / Q000503:physiopathology; D009408:Nerve Compression Syndromes / Q000503:physiopathology; D009414:Nerve Growth Factors / Q000502:physiology; D009416:Nerve Regeneration; D059348:Peripheral Nerve Injuries; D010525:Peripheral Nerves / Q000098:blood supply / Q000503:physiopathology; D012583:Schwann Cells / Q000502:physiology; D013314:Stress, Mechanical; D014855:Wallerian Degeneration; D014947:Wounds and Injuries / Q000145:classification
D009414:Nerve Growth Factors