title: Pregnancy outcome in women with heart disease undergoing induction of labour.
abstract: OBJECTIVE
  To examine the safety and outcome of induction of labour in women with heart disease.
  
  
  METHODS
  Prospective single-centre comparative study.
  
  
  METHODS
  Major university-based medical centre.
  
  
  METHODS
  One hundred and twenty-one pregnant women with heart disease.
  
  
  METHODS
  The sample included all women with acquired or congenital heart disease who attended our High-Risk Pregnancy Outpatient Clinic from 1995 to 2001. The files were reviewed for baseline data, cardiac and obstetric history, course of pregnancy and induction of labour and outcome of pregnancy. Findings were compared between women who underwent induction of labour and those who did not. Forty-seven healthy women in whom labour was induced for obstetric reasons served as controls.
  
  
  METHODS
  Pregnancy outcome.
  
  
  RESULTS
  Of the 121 women with heart disease, 47 (39%) underwent induction of labour. There was no difference in the caesarean delivery rate after induction of labour between the women with heart disease (21%) and the healthy controls (19%). Although the women with heart disease had a higher rate of maternal and neonatal complications than controls (17%vs 2%, P= 0.015), within the study group, there was no difference in complication rate between the patients who did and did not undergo induction of labour.
  
  
  CONCLUSIONS
  Induction of labour is a relatively safe procedure in women with cardiac disease. It is not associated with a higher rate of caesarean delivery than in healthy women undergoing induction of labour for obstetric indications, or with more maternal and neonatal complications than in women with a milder form of cardiac disease and spontaneous labour.
authors.affiliation: Perinatal Division, Department of Obstetrics and Gynecology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel.
authors.forename: Galia
authors.initials: G
authors.lastname: Oron
authors.forename: Rafael
authors.initials: R
authors.lastname: Hirsch
authors.forename: Avi
authors.initials: A
authors.lastname: Ben-Haroush
authors.forename: Moshe
authors.initials: M
authors.lastname: Hod
authors.forename: Yinon
authors.initials: Y
authors.lastname: Gilboa
authors.forename: Ofer
authors.initials: O
authors.lastname: Davidi
authors.forename: Jacob
authors.initials: J
authors.lastname: Bar
mesh_terms: D000328:Adult; D000075202:Contraindications; D005260:Female; D006331:Heart Diseases; D006801:Humans; D007751:Labor, Induced; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular; D011256:Pregnancy Outcome; D011446:Prospective Studies; D012044:Regression Analysis; D012307:Risk Factors