title: Equivalency of culture media for human in vitro fertilization formulated to have the same pH under an atmosphere containing 5% or 6% carbon dioxide.
abstract: Culture media for human in vitro fertilization and early embryonic development were modified to maintain similar pH values under an atmosphere containing 5% or 6% carbon dioxide by adjusting the concentration of sodium bicarbonate. Similar results were obtained with both media groups in a mouse embryo assay and in human in vitro parameters of fertilization and early development and clinical outcomes.
authors.affiliation: SAGE In-Vitro Fertilization Inc, San Clemente, California 92673, USA. patrick.quinn@coopersurgical.com
authors.forename: Patrick
authors.initials: P
authors.lastname: Quinn
authors.forename: Simon
authors.initials: S
authors.lastname: Cooke
mesh_terms: D000328:Adult; D000388:Air / Q000032:analysis*; D000818:Animals; D002245:Carbon Dioxide / Q000032:analysis*; D002626:Chemistry, Pharmaceutical; D003470:Culture Media / Q000737:chemistry*; D010064:Embryo Implantation; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007246:Infertility / Q000628:therapy*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D011247:Pregnancy; D018873:Pregnancy Rate; D011522:Protons; D020554:Sperm Injections, Intracytoplasmic; D013810:Therapeutic Equivalency; D016896:Treatment Outcome
chemical_list: D003470:Culture Media; D011522:Protons; D002245:Carbon Dioxide