Recurrent syncope as presenting symptom of Burkitt's lymphoma at the carotid bifurcation.
Burkitt's lymphoma is rare outside of Africa, and head and neck manifestations of this disease are even more uncommon. We report a case of Burkitt's lymphoma localized at the bifurcation of the right common carotid artery in a 64-year-old man. The presenting symptoms were recurrent syncopes that necessitated a pacemaker, followed by a rapid onset of cranial nerve palsies. The tumor had infiltrated cranial nerves IX, X, XI, and XII and was resected by selective neck dissection. The patient was subsequently treated with a chemotherapeutic regimen consisting of a combination of cytosine arabinoside, vincristine, ifosfamide, prednisone, and an intrathecal application of methotrexate. He also underwent external-beam irradiation of the neck. The patient has been followed up for a period of 42 months and has no evidence of recurrent disease. Repeated diagnostic testing and a coordination of multiple disciplines can speed diagnosis and therapeutic management. The current literature is reviewed and discussed.
Arapakis
Iakovos
I
Department of Otorhinolaryngology-Head and Neck Surgery, University of Freiburg, Freiburg, Germany.
Fradis
Milo
M
Ridder
Gerd Jürgen
GJ
Schipper
Jörg
J
Maier
Wolfgang
W
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002051:Burkitt Lymphoma / Q000150:complications* / Q000628:therapy; D002339:Carotid Arteries; D003389:Cranial Nerve Diseases / Q000209:etiology*; D006258:Head and Neck Neoplasms / Q000150:complications* / Q000628:therapy; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D011882:Radiotherapy, High-Energy; D012008:Recurrence; D013575:Syncope / Q000209:etiology*