title: Hepatic abscesses in cats: 14 cases (1985-2002).
abstract: In this retrospective study, we describe 14 cats diagnosed with hepatic abscesses. The objective of the study was to report the clinical signs, physical examination findings, clinicopathologic findings, and outcomes in affected cats. These findings were then compared with those previously reported in dogs and humans. Clinical signs were vague and included anorexia, lethargy, and weight loss. Only 23% of cats had fever, whereas 31% were hypothermic. Increases in serum activities of alanine aminotransferase and alkaline phosphatase were found in 45 and 18%, respectively, of the 11 cats that had laboratory work performed. Abdominal ultrasound examinations were performed in 7 cats, and abnormalities were found in 71% of them. Four cats had solitary abscesses, all of which were located in the right liver lobes. The other 10 cats had multifocal small abscesses or microabscesses, and all of these cats had clinical signs suggestive of sepsis. Cytologic evaluation of samples obtained by abdominocentesis indicated septic inflammation in 67% of cats in which peritoneal fluid was analyzed. Hepatic abscess cultures yielded polymicrobial growth in 66% of the cats: Escherichia coli was the most commonly cultured organism. Overall mortality rate was 79%. All survivors underwent exploratory laparotomy for partial hepatectomy to resect the abscess followed by medical management. Hepatic abscesses should be considered in cats with signs consistent with sepsis. More routine use of ultrasonography may aid in earlier diagnosis of hepatic abscesses, potentially improving prognosis and outcome.
authors.affiliation: Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108, USA.
authors.forename: Jennifer S
authors.initials: JS
authors.lastname: Sergeeff
authors.forename: P Jane
authors.initials: PJ
authors.lastname: Armstrong
authors.forename: Susan E
authors.initials: SE
authors.lastname: Bunch
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D002371:Cat Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality; D002415:Cats; D004926:Escherichia coli / Q000302:isolation & purification; D005260:Female; D008100:Liver Abscess / Q000453:epidemiology / Q000662:veterinary*; D008297:Male; D008499:Medical Records; D009657:North Carolina / Q000453:epidemiology; D011859:Radiography; D012189:Retrospective Studies; D018805:Sepsis / Q000453:epidemiology / Q000662:veterinary; D014463:Ultrasonography
chemical_list: D000410:Alanine Transaminase; D000469:Alkaline Phosphatase