Is TPO hemineglect the result of unbalanced inhibition?
A neurophysiological hypothesis is offered, together with supporting literature, that hemineglect and/or extinction from a temporo-paneto-occipital lesion (and possibly other lesions) can be understood as the unavailability to consciousness of information well represented in brain, the unavailability being the consequence of temporarily suppressing tonic inhibition of corticothalamic interaction no longer balanced by facilitation from the damaged cortex.
Bogen
Joseph E
JE
University of Southern California, Los Angeles, USA. jbogen@its.caltech.edu
D000818:Animals; D001143:Arousal / Q000502:physiology; D001930:Brain Injuries / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000503:physiopathology*; D003243:Consciousness; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007266:Inhibition, Psychological; D010468:Perceptual Disorders / Q000503:physiopathology*; D013788:Thalamus / Q000503:physiopathology