Stereoselective one-pot synthesis of substituted (4Z)-2-alkyl-4-benzylidene- 4H-1,3-benzothiazines.
Substituted (4Z)-4-benzylidene-2-methyl-4H-1,3-benzothiazines (1). and (4Z)-2-ethyl-4-benzylidene-4H-1,3-benzothiazines (2). were synthesized by direct stereoselective reactions of S-phenyl ethanethioate or S-phenyl propanethioate with substituted benzyl nitriles in the presence of triflic anhydride.
Herrera
Antonio
A
Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Complutense, E-28040 Madrid, Spain.
Martínez-Alvarez
Roberto
R
Ramiro
Pedro
P
Sánchez
Angel
A
Torres
Rosario
R