title: Human challenge pilot study with Cyclospora cayetanensis.
abstract: We describe a pilot study that attempted to infect human volunteers with Cyclospora cayetanensis. Seven healthy volunteers ingested an inoculum of Cyclospora oocysts (approximately 200-49,000 oocysts). The volunteers did not experience symptoms of gastroenteritis, and no oocysts were detected in any stool samples during the 16 weeks volunteers were monitored.
authors.affiliation: Office of Public Health Preparedness and Response, Raleigh, North Carolina, USA. ealfano@ph.co.durham.nc.us
authors.forename: Edith M
authors.initials: EM
authors.lastname: Alfano-Sobsey
authors.forename: Mark L
authors.initials: ML
authors.lastname: Eberhard
authors.forename: John R
authors.initials: JR
authors.lastname: Seed
authors.forename: David J
authors.initials: DJ
authors.lastname: Weber
authors.forename: Kimberly Y
authors.initials: KY
authors.lastname: Won
authors.forename: Eva K
authors.initials: EK
authors.lastname: Nace
authors.forename: Christine L
authors.initials: CL
authors.lastname: Moe
mesh_terms: D000328:Adult; D000818:Animals; D021744:Cyclospora / Q000302:isolation & purification; D021866:Cyclosporiasis / Q000209:etiology*; D005243:Feces / Q000469:parasitology; D006801:Humans; D008875:Middle Aged; D033661:Oocysts / Q000302:isolation & purification; D010865:Pilot Projects