title: Systemic toxoplasmosis in a five-month-old beaver, (Castor canadensis).
abstract: A 5-mo-old orphan beaver, Castor canadensis, died of severe systemic toxoplasmosis during rehabilitation. Histologic lesions included lymphohistiocytic encephalitis, myocarditis, and interstitial pneumonia with multinucleated cells. Intracytoplasmic cysts containing tachyzoites and bradyzoites identified as Toxoplasma gondii by immunohisto-chemistry were present in macrophages, type-II pneumocytes, and endothelial cells. Immunohistochemistry using a polyclonal morbillivirus antibody and transmission electron microscopy of lung revealed no evidence of concurrent paramyxoviral infection, as commonly found in carnivores with toxoplasmosis. Toxoplasmosis may affect young beavers in rehabilitation and zoological settings.
authors.affiliation: Department of Pathobiology and Veterinary Science, University of Connecticut, U-3089, 61 North Eagleville Road, Storrs, Connecticut 06269, USA.
authors.forename: María J
authors.initials: MJ
authors.lastname: Forzán
authors.forename: Salvatore
authors.initials: S
authors.lastname: Frasca
mesh_terms: D000818:Animals; D017809:Fatal Outcome; D007150:Immunohistochemistry / Q000662:veterinary; D008168:Lung / Q000469:parasitology / Q000473:pathology; D008297:Male; D012376:Rodent Diseases / Q000175:diagnosis* / Q000469:parasitology / Q000473:pathology; D012377:Rodentia; D014122:Toxoplasma / Q000302:isolation & purification; D014124:Toxoplasmosis, Animal / Q000175:diagnosis* / Q000473:pathology