title: Local research ethics committees of the Mexican Institute of Social Security: results of a national survey.
abstract: OBJECTIVE
  To identify the structure, composition and work of the local research ethics committees (LRECs) of the Mexican Institute of Social Security (IMSS) in Mexico.
  
  
  METHODS
  A descriptive cross-sectional study was performed that included all LRECs of the IMSS.
  
  
  METHODS
  A total of 335 questionnaires coded in advance were posted to each LREC secretary. The requested information was from January to December 2001.
  
  
  RESULTS
  The response rate was 100%. Two hundred and thirty-eight (71%) LRECs were reported as 'active' during the evaluation period. Although almost all LRECs were composed of diverse professionals, physicians dominated the LRECs' membership. The rejection rate for research projects was lower than 1 per 1000, and less than half of the LRECs held meetings to issue a report of projects' evaluation.
  
  
  CONCLUSIONS
  LRECs need to foster good ethical research; implementation of an audit system to examine their work might help improve LRECs' performance and accountability.
authors.affiliation: Division of Research Evaluation of the National Health Research Council, Mexico City, Mexico. edith.valdez-martinez@lshtm.ac.uk
authors.forename: E
authors.initials: E
authors.lastname: Valdez-Martinez
authors.forename: J
authors.initials: J
authors.lastname: Garduño-Espinosa
authors.forename: H
authors.initials: H
authors.lastname: Martinez-Salgado
authors.forename: J D H
authors.initials: JD
authors.lastname: Porter
mesh_terms: D032802:Committee Membership; D003430:Cross-Sectional Studies; D003625:Data Collection; D028744:Ethics Committees, Research / Q000458:organization & administration*; D005260:Female; D006801:Humans; D008297:Male; D008800:Mexico