Stereoselective synthesis of 1,4-bifunctional compounds by regioselective Pd-catalyzed allylic substitution reaction.
[reaction: see text] Highly stereoselective synthesis of 1,4-bifunctional compounds was accomplished via 1,2-asymmetric induction to alpha-oxyaldehyde followed by regio- and diastereoselective Pd-catalyzed allylic substitution reaction.
Maezaki
Naoyoshi
N
Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
Hirose
Yuki
Y
Tanaka
Tetsuaki
T