[Parameters of carbohydrate metabolism in the myocardium and the liver during general anesthesia with propofol].
The effect of propofol upon carbohydrate metabolism in rat myocardium is manifested by activated anaerobic glucolysis and glycogenolysis leading to devastation of glycogen. In the liver, the drug leads to activated anaerobic glycolysis and decreases the contribution of pentosophosphate pathways of glucose oxidation to carbohydrate metabolism and produces glycogen-preserving action.
Kosnikova
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Vakhidov Surgery Research Center, ul. Farkhadskaya 10, Tashkent, 700115 Uzbekistan.
D000693:Anaerobiosis; D018681:Anesthetics, General / Q000494:pharmacology*; D000818:Animals; D050260:Carbohydrate Metabolism; D005947:Glucose / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism; D006019:Glycolysis; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism*; D015742:Propofol / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
D018681:Anesthetics, General; D006003:Glycogen; D005947:Glucose; D015742:Propofol