title: Vitamin A status of pregnant Nigerian women: relationship to dietary habits and morbidity.
abstract: Vitamin A status of pregnant Nigerian women has been determined by measurement of retinol concentration in plasma samples obtained from pregnant subjects, using a spectrophotometric method. The relationship between vitamin A status, dietary habits and morbidity pattern was also examined. Two hundred (200) consecutive pregnant women registered for antenatal clinic at the Obafemi Awolowo University Teaching Hospitals Complex within a period of eight (8) weeks were recruited as subjects. The subjects were aged 15-43 years (mean 27.2 years), and were at different stages of pregnancy. Semi-structured questionnaires were administered on the subjects to obtain data on dietary habits, present health status and obstetric history. Vitamin A deficiency (plasma retinol concentration < 0.35 micromol/L) is found in 17.5% of the subjects, while 37% and 45.5% have borderline (plasma retinol concentration 0.35-0.70 micromol/L) and normal (plasma retinol concentration > 0.70 micromol/L) vitamin A status respectively. There is a significant relationship between frequent micturition and vitamin A status (chi-square = 0.39: P < 0.05). There is no relationship between maternal age and vitamin A status. Although about 80% of the subjects consumed red palm oil daily, about 64% would heat the oil to smoking for at least 10 minutes, before adding to stew during cooking. Green vegetables were also boiled in hot water before adding to sauce, while liver is consumed on just about three days per month. The findings reported in this study have further strengthened the claim that vitamin A deficiency is fairly prevalent in pregnant Nigerian women, underlining the need for prompt and effective intervention.
authors.affiliation: Department of Chemical Pathology, College of Health Sciences, Obafemi Awolowo University, PO Box 1089, OAU Post Office, Ile-Ife, Osun State, Nigeria.
authors.forename: O A
authors.initials: OA
authors.lastname: Ajose
authors.forename: D A
authors.initials: DA
authors.lastname: Adelekan
authors.forename: E O
authors.initials: EO
authors.lastname: Ajewole
mesh_terms: D000293:Adolescent; D000328:Adult; D004032:Diet; D005260:Female; D006801:Humans; D009549:Nigeria / Q000453:epidemiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control*; D011261:Pregnancy Trimester, First; D011795:Surveys and Questionnaires; D014802:Vitamin A Deficiency / Q000097:blood / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control*