title: A case of severe leptospirosis with pancytopaenia.
abstract: Pancytopaenia is a rare clinical presentation of severe leptospirosis. We would like to report a case of severe leptospirosis that progressed to pancytopaenia despite initial penicillin therapy. The patient needed a second course of antibiotic with doxycycline to improve his persistent symptoms and cytopaenia. Persistent pancytopaenia in severe leptospirosis and its management were reviewed.
authors.affiliation: Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur.
authors.forename: P C
authors.initials: PC
authors.lastname: Bee
authors.forename: S K
authors.initials: SK
authors.lastname: Chow
authors.forename: L H
authors.initials: LH
authors.lastname: Tan
mesh_terms: D004318:Doxycycline / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D006801:Humans; D007922:Leptospirosis / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D010198:Pancytopenia / Q000188:drug therapy / Q000209:etiology*; D010406:Penicillins / Q000008:administration & dosage
chemical_list: D010406:Penicillins; D004318:Doxycycline