The critical micelle concentrations of lysophosphatidic acid and sphingosylphosphorylcholine.
The critical micelle concentrations (CMC) of lysophosphatidic acid (LPA) and sphingosylphosphorylcholine (SPC) were measured by isothermal titration calorimetry. The CMC of LPA decreases with salt concentration and acyl chain length. In water at 25 degrees C, the CMC values of 1-acyl-2-lyso-sn-glycero-3-phosphatidic acid are 1.850, 0.540, 0.082, and 0.346 mM, respectively, when the acyl group is myristoyl, palmitoyl, stearoyl, and oleoyl. The CMC of SPC in 10 mM sodium phosphate buffer, pH 7.4, at 25 degrees C was 0.158 mM, and did not change with an increase in salt concentration.
Li
Zaiguo
Z
Department of Chemistry and Biochemistry, Queens College of The City University of New York, 65-30 Kissena Blvd., Flushing 11367-1597, USA.
Mintzer
Evan
E
Bittman
Robert
R
D008246:Lysophospholipids / Q000737:chemistry*; D008823:Micelles; D015394:Molecular Structure; D010767:Phosphorylcholine / Q000031:analogs & derivatives* / Q000737:chemistry*; D012965:Sodium Chloride / Q000494:pharmacology; D013110:Sphingosine / Q000031:analogs & derivatives* / Q000737:chemistry*; D014867:Water / Q000737:chemistry
D008246:Lysophospholipids; D008823:Micelles; D014867:Water; C005356:sphingosine phosphorylcholine; D010767:Phosphorylcholine; D012965:Sodium Chloride; D013110:Sphingosine; C032881:lysophosphatidic acid