title: New rapamycin derivatives by precursor-directed biosynthesis.
authors.affiliation: School of Chemistry, University of Exeter, Stocker Road, Exeter, EX4 4QD, UK. P.Lowden@bbk.ac.uk
authors.forename: Philip A S
authors.initials: PA
authors.lastname: Lowden
authors.forename: Günter A
authors.initials: GA
authors.lastname: Böhm
authors.forename: Su
authors.initials: S
authors.lastname: Metcalfe
authors.forename: James
authors.initials: J
authors.lastname: Staunton
authors.forename: Peter F
authors.initials: PF
authors.lastname: Leadlay
mesh_terms: D002264:Carboxylic Acids / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D007536:Isomerism; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009097:Multienzyme Complexes / Q000235:genetics / Q000378:metabolism; D011355:Prodrugs; D020123:Sirolimus / Q000737:chemistry* / Q000378:metabolism*; D012997:Solvents / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D013302:Streptomyces
chemical_list: D002264:Carboxylic Acids; D009097:Multienzyme Complexes; D011355:Prodrugs; D012997:Solvents; D020123:Sirolimus