title: Nitric oxide metabolites and adrenomedullin in human breast milk.
abstract: We found high concentrations of nitrite/nitrate (166-1460 micromol/l) in 43 milk samples obtained from 32 women during postpartum days 1-8, which indicates enhanced mammary nitric oxide (NO) secretion. We detected adrenomedullin (AM) (2.7-20.7 pmol/l) only in 9 of the 43 samples using highly specific immunoradiometric assay. It is uncertain whether the entire adrenomedullin is actively secreted in human milk.
authors.affiliation: Department of Pediatrics, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
authors.forename: Naoko
authors.initials: N
authors.lastname: Ohta
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Tsukahara
authors.forename: Yusei
authors.initials: Y
authors.lastname: Ohshima
authors.forename: Manabu
authors.initials: M
authors.lastname: Nishii
authors.forename: Yasuyo
authors.initials: Y
authors.lastname: Ogawa
authors.forename: Kyouichi
authors.initials: K
authors.lastname: Sekine
authors.forename: Kenkou
authors.initials: K
authors.lastname: Kasuga
authors.forename: Mitsufumi
authors.initials: M
authors.lastname: Mayumi
mesh_terms: D053607:Adrenomedullin; D005260:Female; D006801:Humans; D015592:Immunoradiometric Assay; D008895:Milk, Human / Q000737:chemistry*; D009566:Nitrates / Q000032:analysis; D009569:Nitric Oxide / Q000378:metabolism*; D009573:Nitrites / Q000032:analysis; D010455:Peptides / Q000032:analysis*; D049590:Postpartum Period; D013997:Time Factors
chemical_list: D009566:Nitrates; D009573:Nitrites; D010455:Peptides; D053607:Adrenomedullin; D009569:Nitric Oxide