Occlusion of pseudoaneurysms using human or bovine thrombin using contrast-enhanced ultrasound guidance.
Percutaneous thrombin occlusion of pseudoaneurysms complicating invasive coronary interventions has emerged as a useful therapeutic tool. To facilitate thrombin occlusion and make the procedure even more secure, preinjection of echo contrast medium during duplex ultrasound was tested in 132 patients. Complete and immediate occlusion of the pseudoaneurysm was achieved in 99.2% (131 of 132 patients). No complications related to the injection of thrombin were documented. Contrast-enhanced ultrasound-guided thrombin occlusion was a safe and effective therapeutic option. In aneurysms with complex morphology or multiple cavities, preinjection of contrast medium was helpful for documenting the flow pattern.
Grewe
Peter Hubert
PH
Clinic II (Cardiology/Angiology), Berufsgenossenschaftliche Kliniken Bergmannsheil Bochum, University of Bochum, Bochum, Germany. petergrewe@aol.com
Mügge
Andeas
A
Germing
Alfried
A
Harrer
Elisabeth
E
Baberg
Henning
H
Hanefeld
Christoph
C
Deneke
Thomas
T
D017541:Aneurysm, False / Q000000981:diagnostic imaging* / Q000628:therapy*; D000818:Animals; D002417:Cattle; D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging*; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D013917:Thrombin / Q000008:administration & dosage*; D018615:Ultrasonography, Doppler, Color
D003287:Contrast Media; D006490:Hemostatics; D013917:Thrombin