Combined relaxation and displacement experiment: a fast method to acquire T2, diffusion and velocity maps.
A fast method for quantitative imaging of T2 and displacement (flow and diffusion) is presented. The pulse sequence combines multi-PGSE NMR with multi-echo acquisition and compensates for flow effects in the read gradient and diffusion during multi-echo trains. The impact of the gradient pulses in a multi-echo train on the signal phase and amplitude is discussed. It is shown that separate T2 and displacement images with microscopic resolution can be obtained within minutes. The capability for 3D flow imaging is demonstrated. The sequence is then used to investigate forced detachment of a biofilm in a tube.
Manz
Bertram
B
Arbeitsgruppe Magnetische Resonanz, Fraunhofer-Institut für Biomedizinische Technik, Ensheimer Strasse 48, 66386 St. Ingbert, Germany. betram.manz@ibmt.fraunhofer.de
D000465:Algorithms; D018441:Biofilms; D002448:Cell Adhesion / Q000502:physiology; D038524:Diffusion Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D007089:Image Enhancement / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation / Q000379:methods*; D009068:Movement; D019047:Phantoms, Imaging; D012212:Rheology / Q000379:methods*; D012815:Signal Processing, Computer-Assisted; D014867:Water / Q000737:chemistry*
D014867:Water