[Tolterodine for bladder spasm caused by the indwelling catheter after prostate operation].
OBJECTIVE
To evaluate the efficacy of tolterodine on bladder spasm caused by the indwelling catheter after prostate operation.


METHODS
Eighty-two patients with bladder spasm caused by the indwelling catheter after prostate operation received tolterodine (2 mg twice daily), until 24 hours before the removal of the catheter.


RESULTS
After 24 hours of treatment, bladder spasm was alleviated totally in 21 patients (25.6%), partially in 45 (54.9%), and unrelieved in 16 (19.5%). After 72 hours of treatment, bladder spasm was alleviated totally in 45 patients (54.9%), partially in 30 (36.6%), and unrelieved in 7 (8.5%). No severe adverse events occurred during the treatment.


CONCLUSIONS
The tolterodine therapy for patients with bladder spasm caused by the indwelling catheter after prostate operations is rapid, effective, persistent and safe.
Chen
Qi
Q
Department of Urology, Affiliated Renji Hospital, Shanghai Second Medical University, Shanghai 200127, China. totorocky@sina.com
Xue
Wei
W
Wang
Yuantian
Y
Lu
Jianwei
J
Huang
Yiran
Y
D000368:Aged; D000369:Aged, 80 and over; D001559:Benzhydryl Compounds / Q000627:therapeutic use*; D002408:Catheters, Indwelling / Q000009:adverse effects*; D003408:Cresols / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010665:Phenylpropanolamine; D013035:Spasm / Q000188:drug therapy*; D000068737:Tolterodine Tartrate; D020728:Transurethral Resection of Prostate; D001745:Urinary Bladder Diseases / Q000188:drug therapy*; D014546:Urinary Catheterization / Q000009:adverse effects*
D001559:Benzhydryl Compounds; D003408:Cresols; D010665:Phenylpropanolamine; D000068737:Tolterodine Tartrate