[New vessels formation within intramural leiomyomata].
OBJECTIVE
The vessels of uterine leiomyomata seem to control the growth of the tumour. The aim of the study was to analyze the angioarchitecture of intramural leiomyomata and to observe vascular sprouting of the growing vessels in these tumors.


METHODS
28 myomatous uteri collected upon autopsy were injected via afferent vessels with Mercox resin and corroded after polymerisation of the resin.


RESULTS
Two types of tumour vascularization were distinguished: tumors with few vessels invading the leiomyoma with few side branches and tumours with dense vascular "capsule" which was a source of small vessels supplying the tumour. Vascular sprouts were observed in majority of studied tumors.


CONCLUSIONS
Pre-existing vessels undergo regression and new vessels grow from the periphery, as well as new vessels arise in the process of angiogenesis within the tumors.
Walocha
Jerzy A
JA
Katedra Anatomii CM UJ w Krakowie.
Miodoński
Adam J
AJ
Tsibris
John M
JM
Skrzat
Janusz
J
D000328:Adult; D001344:Autopsy; D001808:Blood Vessels / Q000473:pathology* / Q000648:ultrastructure*; D002196:Capillaries / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000098:blood supply* / Q000473:pathology; D008855:Microscopy, Electron, Scanning; D009389:Neovascularization, Pathologic; D014594:Uterine Neoplasms / Q000098:blood supply* / Q000473:pathology