title: Traditional medicine in north Côte-d'Ivoire: screening of 50 medicinal plants for antibacterial activity.
abstract: Sixty-seven crude ethanol extracts from 50 plants (31 families), which are used in North Côte-d'Ivoire as traditional remedies for bacterial diseases, were screened for in vitro activity against Gram negative (Escherichia coli and Pseudomonas aeruginosa) and Gram positive (Staphylococcus aureus, Enterococcus faecalis, Streptococcus pyogenes and Bacillus subtilis) bacteria. Thirty-one extracts showed antibacterial activity only on Gram positive bacteria. Of these, 10 extracts from 10 plant species had a promising level of activity against bacteria including strains resistant to antibiotics such as aminosides, penicillin M, macrolides, lincosamide and streptrogramin B. The most active was Erythrina senegalensis DC (Fabaceae) followed by Bobgunnia madagascariensis (Desv.) J.H. Kirkbr. & Wiersema (Caesalpinaceae), Waltheria lanceolata R. Br. ex Mast. (Sterculiaceae), Uapaca togoensis Pax. (Euphorbiaceae), Ximenia americana L. (Olacaceae), Khaya senegalensis (Ders.) A. Juss. (Meliaceae), Lannea acida A. Rich. (Anacardiaceae), Cissus populnea Guill. & Perr. (Vitaceae), Keetia hispida (Benth.) Bridson (Rubiaceae) and Ficus thonningii (Miq.) A. Rich. (Moraceae). This is the first report of the antibacterial potency of these 10 plant species on a range of bacteria. The results provided evidence that some of the studied plants might indeed be potential sources of new antibacterial agents, also against some antibiotic-resistant strains.
authors.affiliation: Laboratoire de Botanique, UFR Biosciences, Université de Cocody, Abidjan, Côte-d'Ivoire. mamidou.kone@csrs.ci
authors.forename: W M
authors.initials: WM
authors.lastname: Koné
authors.forename: K Kamanzi
authors.initials: KK
authors.lastname: Atindehou
authors.forename: C
authors.initials: C
authors.lastname: Terreaux
authors.forename: K
authors.initials: K
authors.lastname: Hostettmann
authors.forename: D
authors.initials: D
authors.lastname: Traoré
authors.forename: M
authors.initials: M
authors.lastname: Dosso
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D007560:Cote d'Ivoire; D004353:Drug Evaluation, Preclinical / Q000379:methods; D016488:Medicine, African Traditional; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology; D018514:Plant Structures; D010946:Plants, Medicinal
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts