[Disturbances in the intestinal microflora and immune system in children with vitiligo].
A total of 91 children, aged 3-16 years, with vitiligo were examined. These examinations showed that the total number of T lymphocytes decreased irrespective of the degree of intestinal dysbacteriosis. The average number of T suppressors increased as dysbiotic changes in the intestine became more profound. The amount of natural killers, B lymphocytes, as well as the content of IgG and IgA (p < 0.001), increased irrespectively of the degree of intestinal dysbacteriosis. Thus the unbalance of the immunity system and dysbiotic changes in the intestine of children having vitiligo were Inter-related.
Mukhamedov
I M
IM
Pediatric Medical Institute, 1st State Medical Institute, Tashkent, Republic of Uzbekistan.
Shadiev
Kh K
KhK
Abdullaev
M I
MI
Aliev
Sh R
ShR
Ergasheva
Kh E
KhE
D000293:Adolescent; D001402:B-Lymphocytes / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D018450:Disease Progression; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007410:Intestinal Diseases / Q000175:diagnosis / Q000382:microbiology*; D007420:Intestine, Large / Q000382:microbiology*; D007694:Killer Cells, Natural / Q000276:immunology; D018655:Lymphocyte Count; D016131:Lymphocyte Subsets / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D014820:Vitiligo / Q000097:blood / Q000276:immunology* / Q000382:microbiology*
D007070:Immunoglobulin A; D007074:Immunoglobulin G