[Cellular immunity in patients with urogenital chlamydiosis].
Abnormalities in the cellular immunity chain (CIC) were found in 63.04% of patients with urogenital chlamydiosis (UGC) within a study of cellular immunity in patients with the above pathology. According to the study results, the below listed were the main CIC impairments: a lack or reaction to the inducer of T-helpers (CD3+ and CD4+), and to activated T-lymphocytes (CD3+ and CD25+); higher counts of cytotoxic T-lymphocytes (CD3+ and CD8+), a higher content of B-lymphocytes (CD3+ and CD19+, and lower counts of NK-cells (CD3- and CD56+). However, research of the lymphocyte subpopulation alone is not enough to evaluate adequately the immune system of a patient. In order to choose an adequate scheme for the treatment of UGH patients it is necessary to undertake a study of the immune status that should comprise, apart CIC investigations, the following: humoral immunity, phagocyte function, factors of non-specific body resistance and cytokine status.
Mikolauskas
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D000328:Adult; D002690:Chlamydia Infections / Q000276:immunology*; D005260:Female; D052776:Female Urogenital Diseases / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D008875:Middle Aged