Idiopathic stuttering priapism: recovery of detumescence mechanism with temporal use of antiandrogen.
We report a case of idiopathic stuttering priapism in a 56-year-old Japanese man. We treated his recurrent priapism in stepwise fashion by withdrawal of the alpha/beta-blocker he used for hypertension, administration of low doses of an antiandrogen and baclofen, and finally by increasing the dose of antiandrogen, which lowered his testosterone to the castration level and was effective in preventing priapism. After 6 months of antiandrogen treatment, his erectile function gradually recovered to the baseline level, and he had no recurrence of priapism during the following 6 months without any medication.
Yamashita
Nana
N
Department of Urology, Sapporo Medical University, Chuo-ku, Sapporo, Japan.
Hisasue
Shin-ichi
S
Kato
Ryuichi
R
Masumori
Naoya
N
Takahashi
Atsushi
A
Itoh
Naoki
N
Tsukamoto
Taiji
T
D001418:Baclofen / Q000008:administration & dosage; D001784:Blood Gas Analysis; D002715:Chlormadinone Acetate / Q000008:administration & dosage* / Q000009:adverse effects; D007172:Erectile Dysfunction / Q000139:chemically induced; D006801:Humans; D007511:Ischemia / Q000150:complications / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D010413:Penis / Q000098:blood supply; D010656:Phenylephrine / Q000008:administration & dosage; D011317:Priapism / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D012074:Remission Induction; D055502:Secondary Prevention; D012965:Sodium Chloride / Q000008:administration & dosage; D013739:Testosterone / Q000097:blood; D007507:Therapeutic Irrigation
D002715:Chlormadinone Acetate; D010656:Phenylephrine; D013739:Testosterone; D012965:Sodium Chloride; D001418:Baclofen