title: Neuroimaging in disorders of cortical development.
abstract: Malformations of cortical development are important causes of developmental delay and epilepsy. They are classified by the presumed stage during which normal development is interrupted: neuronal proliferation and differentiation, neuronal migration, and late migration/cortical organization. This article discusses the important malformations in each of these groups, how and why the malformations develop, and their imaging findings. A better understanding of these disorders helps in genetic counseling of the parents and may help in the treatment of associated epilepsy.
authors.affiliation: Department of Radiology, University of California at San Francisco, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143, USA. jimb@radiology.ucsf.edu
authors.forename: A James
authors.initials: AJ
authors.lastname: Barkovich
authors.forename: Charles A
authors.initials: CA
authors.lastname: Raybaud
mesh_terms: D002540:Cerebral Cortex / Q000002:abnormalities* / Q000196:embryology*; D006801:Humans; D009421:Nervous System Malformations / Q000000981:diagnostic imaging / Q000196:embryology* / Q000473:pathology*; D011859:Radiography