title: [Identification of sentinel lymph nodes in thyroid carcinoma].
abstract: Sentinel lymph node (SLN) was defined as the first lymph node that the tumor would drain to, within that tumors regional lymphatic basin. In 1998, Kelemen and coworkers have published the first results on SLN lymphonodectomy in thyroid carcinomas. Different methods have been used in a goal of lymphatic mapping (application of vital blue dye and/or radiocolloid). In a period from 2001 to 2003 we have performed SLN biopsy in 64 patients with thyroid tumors. There were 12 cases of thyroid carcinoma. SLN identification rate was 73.44%. We found no false positive or negative results on definitive histopathology. The impact of lymph node metastases in differentiated thyroid carcinoma is still controversial. The management of cervical lymph nodes varies from berry picking to modified radical neck dissection. There is a significant disproportion in percentage of pre and intraoperatively enlarged lymph nodes (27-45%) and histologically confirmed lymph node metastases (80-90%) in papillary thyroid carcinoma. In the current literature the average rate of SLN identification is 91% (66-100%) and when identified, the SLN accurately predicts the disease status of the neck in most patients (80-100%). The SLN biopsy for thyroid carcinoma is good and feasible technique for estimating the cervical lymph node status.
authors.affiliation: Sluzba hirurgije, Institut za onkologiju i radiologiju Srbije.
authors.forename: R
authors.initials: R
authors.lastname: Dzodic
authors.forename: I
authors.initials: I
authors.lastname: Marković
authors.forename: M
authors.initials: M
authors.lastname: Inić
authors.forename: N
authors.initials: N
authors.lastname: Jokić
authors.forename: M
authors.initials: M
authors.lastname: Zegarac
authors.forename: I
authors.initials: I
authors.lastname: Djuricic
authors.forename: Z
authors.initials: Z
authors.lastname: Milovanović
authors.forename: G
authors.initials: G
authors.lastname: Pupic
authors.forename: N
authors.initials: N
authors.lastname: Jovanović
mesh_terms: D002277:Carcinoma / Q000175:diagnosis / Q000556:secondary*; D004396:Coloring Agents; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D008207:Lymphatic Metastasis / Q000175:diagnosis*; D011877:Radionuclide Imaging; D021701:Sentinel Lymph Node Biopsy; D013964:Thyroid Neoplasms / Q000473:pathology*
chemical_list: D004396:Coloring Agents