After the Women's Health Initiative: Postmenopausal women's experiences with discontinuing estrogen replacement therapy.
OBJECTIVE
To gather information about women's responses to the publication of the Women's Health Initiative (WHI) and to determine what proportion of women stopped hormone replacement therapy (HRT) and whether the technique of discontinuation affected the recurrence of menopausal symptoms.


METHODS
73 subjects were identified through VA pharmacy records and were mailed a letter detailing the results of the WHI. A follow-up questionnaire was mailed several months later to the same population.


RESULTS
48 subjects responded and were eligible for inclusion in the study. Mean age was 62 years; 37 (77%) stopped taking HRT, and 11 (23%) continued. Twenty patients stopped abruptly, and 17 tapered off HRT. Eight (40%) of the group who stopped abruptly experienced recurrent menopausal symptoms, compared with 12 (71%) of the group who tapered HRT.


CONCLUSIONS
In a population of women veterans, 77% stopped HRT after publication of the WHI. Tapering HRT, rather than stopping abruptly, did not reduce the recurrence of menopausal symptoms in our patient population.
Haskell
Sally G
SG
Yale University School of Medicine, Department of Internal Medicine, New Haven, Connecticut, USA. Sally.Haskell@med.VA.Gov
D000368:Aged; D000369:Aged, 80 and over; D001294:Attitude to Health; D003327:Coronary Disease / Q000517:prevention & control; D015914:Estrogen Replacement Therapy / Q000523:psychology* / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008593:Menopause / Q000187:drug effects; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000517:prevention & control; D010349:Patient Compliance; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014481:United States; D016387:Women's Health