Thyroglossal duct cyst with papillary carcinoma: what must be done?
OBJECTIVE
To present a report series of five cases, compare their clinical evolution, and establish the appropriate treatment.


METHODS
A retrospective study was performed with the clinical records from three health institutions in Mexico City, Mexico, in order to search for patients with histologic diagnosis of thyroglossal duct carcinoma and were classified by different risk stratifications to compare their outcome.


RESULTS
We found five patients, three females and two males, mean age 49 years. Four were treated by Sistrunk's procedure, total thyroidectomy, radioiodine ablation, and thyroxine suppression; one patient underwent Sistrunk's procedure only. Four patients were classified in the low- and median-risk group and had good outcome; one patient was in the high-risk group and had poor outcome.


CONCLUSIONS
The thyroglossal duct cyst must be studied in the adult population through fine-needle aspiration biopsy (FNAB) and a frozen section in cases in which FNAB is inconclusive or unavailable. When a diagnosis of a thyroglossal cyst carcinoma is made, an evaluation of the thyroid gland during surgery must be done as well as a careful examination to identify suspicious lymph nodes and neck dissection should be reserved for confirmed adenopathies. When an thyroglossal duct cyst has been excised using Sistrunk's procedure and the definitive histologic analysis reports malignancy, the thyroid gland must be studied. The extension of the surgery must be handled according to the criteria established for differentiated thyroid cancer.
Luna-Ortiz
Kuauhyama
K
Department of Head and Neck Surgery, Instituto Nacional de Cancerología, Mexico City, Mexico. kuauhyama@starmedia.com
Hurtado-Lopez
Luis Mauricio
LM
Valderrama-Landaeta
Jose Luis
JL
Ruiz-Vega
Alfredo
A
D000328:Adult; D002291:Carcinoma, Papillary / Q000150:complications* / Q000628:therapy; D006801:Humans; D008297:Male; D008499:Medical Records; D008800:Mexico; D008875:Middle Aged; D012189:Retrospective Studies; D013955:Thyroglossal Cyst / Q000150:complications* / Q000628:therapy; D013964:Thyroid Neoplasms / Q000150:complications* / Q000628:therapy; D016896:Treatment Outcome