title: Subconjunctival antibiotics for acute postcataract extraction endophthalmitis--is it necessary?
abstract: OBJECTIVE
  To evaluate the efficacy of adjunctive subconjunctival antibiotic injection in the treatment of acute postcataract extraction endophthalmitis.
  
  
  METHODS
  Retrospective cohort study.
  
  
  METHODS
  Patients who presented with hand motions or better vision and received subconjunctival antibiotics (SC+ group) were compared with those who did not (SC- group) in the treatment of acute postoperative endophthalmitis.
  
  
  RESULTS
  The rate of obtaining a final vision of 20/40 or better was 60% in the SC+ group (n = 25) compared with 72% in the SC- group (n = 18) (P =.69), and the mean change in logMAR was -1.36 (improvement) versus -1.34 (P =.93). Based on a linear regression model controlling for presenting vision, there was no statistical difference in the mean logMAR change between the two groups (P =.73).
  
  
  CONCLUSIONS
  Subconjunctival antibiotic injection as an adjunct to intravitreal antibiotics was unassociated with treatment benefit in patients with acute postoperative endophthalmitis presenting with vision of hand motions or better.
authors.affiliation: Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, 53226, USA.
authors.forename: Mohan N
authors.initials: MN
authors.lastname: Iyer
authors.forename: Dennis P
authors.initials: DP
authors.lastname: Han
authors.forename: Hyun J
authors.initials: HJ
authors.lastname: Yun
authors.forename: Dan
authors.initials: D
authors.lastname: Eastwood
authors.forename: Judy E
authors.initials: JE
authors.lastname: Kim
authors.forename: Thomas B
authors.initials: TB
authors.lastname: Connor
authors.forename: William J
authors.initials: WJ
authors.lastname: Wirostko
authors.forename: Sundeep
authors.initials: S
authors.lastname: Dev
mesh_terms: D000208:Acute Disease; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002387:Cataract Extraction; D017024:Chemotherapy, Adjuvant; D015331:Cohort Studies; D003228:Conjunctiva / Q000187:drug effects*; D009877:Endophthalmitis / Q000188:drug therapy* / Q000382:microbiology; D015818:Eye Infections, Bacterial / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D007267:Injections; D011183:Postoperative Complications / Q000188:drug therapy* / Q000382:microbiology; D012189:Retrospective Studies; D014822:Vitreous Body / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents