title: Multifocal primary intracerebral malignant fibrous histiocytoma--case report.
abstract: A 58-year-old female presented with a unique case of multifocal primary intracerebral malignant fibrous histiocytoma (MFH) manifesting as partial seizure. Neuroimaging showed a mass lesion in the right frontal lobe, which was totally removed. The histological diagnosis was MFH. Follow-up neuroimaging one month after surgery showed another lesion rapidly growing in the left frontal lobe. This lesion was totally removed, and identified as MFH. Her condition gradually worsened. Neuroimaging performed 3 months after first operation revealed bilateral recurrence. She died of respiratory failure 7 months after the initial diagnosis of MFH. Primary intracranial MFH is an extremely rare entity with only 31 cases of solitary tumor previously reported.
authors.affiliation: Department of Neurosurgery, Juntendo University, Juntendo Urayasu Hospital, Urayasu, Chiba.
authors.forename: Takashi
authors.initials: T
authors.lastname: Mitsuhashi
authors.forename: Mitsuya
authors.initials: M
authors.lastname: Watanabe
authors.forename: Yukoh
authors.initials: Y
authors.lastname: Ohara
authors.forename: Shizuo
authors.initials: S
authors.lastname: Hatashita
authors.forename: Hideo
authors.initials: H
authors.lastname: Ueno
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008875:Middle Aged