title: Trabeculectomy outcomes in a Malaysian general hospital.
abstract: A retrospective study was conducted at the Hospital Sultanah Aminah Johor Bahru to determine the outcome of trabeculectomy surgeries over a period of 4 years. One hundred and two eyes were followed up to a maximum of 63 months (mean 34.2 months). The 2-year survival rates for plain trabeculectomies, 5-Fluorouracil augmented trabeculectomies and Mitomycin-C augmented trabeculectomies were 52.9%, 27.3% and 60.5% respectively. The commonest complications noted were cataract formation (25%) and hyphaema (11%). Mitomycin-C induced complications were rarely seen. At last follow-up, 54% of eyes had intraocular pressures below 21 mmHg without medication, while 34% of eyes had intraocular pressures below 21 mmHg with medication. Vitreous at the trabeculectomy site was a statistically significant predictor of operative failure.
authors.affiliation: Department of Ophthalmology, Hospital Sultanah Aminah, Johor Bahru.
authors.forename: S T
authors.initials: ST
authors.lastname: Hooi
authors.forename: S H
authors.initials: SH
authors.lastname: Hooi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000963:Antimetabolites / Q000008:administration & dosage; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D005901:Glaucoma / Q000188:drug therapy / Q000601:surgery*; D006769:Hospitals, General; D006801:Humans; D008296:Malaysia; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D019384:Nucleic Acid Synthesis Inhibitors / Q000008:administration & dosage; D011183:Postoperative Complications; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D000963:Antimetabolites; D019384:Nucleic Acid Synthesis Inhibitors; D016685:Mitomycin; D005472:Fluorouracil