title: Squash smear findings of spherical amyloid in pituitary prolactinoma. A case report.
abstract: BACKGROUND
  Pituitary prolactinoma containing spherical amyloid is rare. Squash smear findings of spherical amyloid in pituitary prolactinoma are characteristic.
  
  
  METHODS
  A 25-year-old woman presented with a pituitary tumor. The intraoperative squash smear showed abundant, homogeneous, eosinophilic material with multiple prominent striations. The scattered atypical cells in the periphery contained an irregular, bizarre nucleus; coarse chromatin; occasional prominent nucleoli; rare cytoplasm; and prolactin immunoreactivity.
  
  
  CONCLUSIONS
  The characteristic squash smear findings should be helpful in the diagnosis of this rare tumor.
authors.affiliation: Department of Pathology, College of Medicine, Yonsei University, Seoul, South Korea.
authors.forename: Se Hoon
authors.initials: SH
authors.lastname: Kim
authors.forename: Sun Ho
authors.initials: SH
authors.lastname: Kim
authors.forename: Seung-Koo
authors.initials: SK
authors.lastname: Lee
authors.forename: Tai Seung
authors.initials: TS
authors.lastname: Kim
mesh_terms: D000328:Adult; D000682:Amyloid / Q000032:analysis*; D001718:Birefringence; D003224:Congo Red / Q000378:metabolism; D003581:Cytodiagnosis; D005260:Female; D006801:Humans; D007430:Intraoperative Care; D008279:Magnetic Resonance Imaging; D008859:Microscopy, Polarization; D010503:Periodic Acid-Schiff Reaction; D010911:Pituitary Neoplasms / Q000737:chemistry* / Q000000981:diagnostic imaging / Q000473:pathology*; D015175:Prolactinoma / Q000737:chemistry* / Q000473:pathology*; D011859:Radiography; D013048:Specimen Handling
chemical_list: D000682:Amyloid; D003224:Congo Red