title: [Genetic polymorphisms of short tandem repeat loci D3S1358, D13S317, D5S818 from Nongqu Mongolia].
abstract: OBJECTIVE
  To understand the allele structure and genetic polymorphism at D3S1358, D13S317, D5S818 short tandem repeats (STRs) loci in Nongqu Mongolian of China, and to construct a preliminary database.
  
  
  METHODS
  The allele frequencies of the three STRs loci in 291 unrelated individuals from Nongqu Mongolian were analyzed by polymerase chain reaction and polyacrylamide gel electrophoresis.
  
  
  RESULTS
  Six, ten, and eight alleles were observed at D3S1358, D13S317, D5S818, respectively, and all 3 loci met Hardy-Weinberg equilibrium. The statistical analysis of 3 STR loci showed the heterozygosity >or=0.7332, the polymorphic information content >or=0.6884; the combined discrimination power and the probabilities of paternity exclusion were 0.9991 and 0.9806 respectively.
  
  
  CONCLUSIONS
  All three of the loci in this study were found to have high heterozygosity and polymorphic information content, so they could provide useful markers for genetic purposes. These results could serve as valuable data to enrich the Mongolian genetic database and play an important role in Chinese population genetic application.
authors.affiliation: Research Center of Molecular Biology, Inner Mongolia Medical College, Huhehaote, Inner Mongolian Autonomous Region, 010059 PR China. spliu9@163.com
authors.forename: Shu-ping
authors.initials: SP
authors.lastname: Liu
authors.forename: Xiu-lan
authors.initials: XL
authors.lastname: Su
authors.forename: Li-fu
authors.initials: LF
authors.lastname: Bi
authors.forename: Cai-ping
authors.initials: CP
authors.lastname: Li
authors.forename: Lin
authors.initials: L
authors.lastname: Qiu
authors.forename: Feng-qi
authors.initials: FQ
authors.lastname: Wang
mesh_terms: D002874:Chromosome Mapping; D006801:Humans; D008986:Mongolia / Q000208:ethnology; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences