[Clinical observation of "dan shao tang" in treating mesangial proliferative glomerulonephritis of deficiency of yin with damp-heat symptom].
OBJECTIVE
To explore the effect of "Dan Shao Tang" (DST) on mesangial proliferative glomerulonephritis (MsPGN) of deficiency of Yin with damp-heat symptom.


METHODS
90 patients with MsPGN of deficiency of Yin with damp-heat symptom were randomly divided into two groups. 54 patients in treatment group were treated with DST and western medicine, and 36 patients in control group were treated only with western medicine. We observed the effect and indexes change including renal function, proteinuria, hematuria, lipid before and after treatment.


RESULTS
After three months treatment, the general effective rate in treatment group was 75.93%, which was markedly higher than that in control group (47.22%, P < 0.01). Treatment group is obviously better than control group on decreasing proteinuria and hematuria, improving renal function, ameliorating lipid metabolism (P < 0.05).


CONCLUSIONS
DST is effective on MsPGN of deficiency of Yin with damp-heat symptom.
Wu
Xinlin
X
First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080.
Li
Junbiao
J
Liu
Benliu
B
D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D000368:Aged; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D015432:Glomerulonephritis, Membranoproliferative / Q000188:drug therapy*; D006801:Humans; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D011241:Prednisone / Q000627:therapeutic use*; D016710:Yin Deficiency / Q000188:drug therapy
D000276:Adjuvants, Immunologic; D004365:Drugs, Chinese Herbal; D011241:Prednisone