title: Rhodium(I)-catalyzed ene-allene carbocyclization strategy for the formation of azepines and oxepines.
abstract: [reaction: see text] A novel strategy for the preparation of seven-membered heterocyclic compounds has been realized. Treatment of ene-allene 1 with a catalytic quantity of rhodium biscarbonyl chloride dimer affords the cyclization product 2 in moderate to high yields. The scope and limitations of this new method are currently under investigation, and the results obtained to date are discussed within.
authors.affiliation: Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA. kbrummond@pitt.edu
authors.forename: Kay M
authors.initials: KM
authors.lastname: Brummond
authors.forename: Hongfeng
authors.initials: H
authors.lastname: Chen
authors.forename: Branko
authors.initials: B
authors.lastname: Mitasev
authors.forename: Anthony D
authors.initials: AD
authors.lastname: Casarez