title: Identification of downstream mechanisms involved in PEDF'S activity in the retina by large scale gene expression profiling.
authors.affiliation: University of Missouri-Kansas City, Pharmaceutical Sciences, Kansas City, MO 64110, USA. jttink@aol.com
authors.forename: Joyce
authors.initials: J
authors.lastname: Tombran-Tink
authors.forename: Nuria
authors.initials: N
authors.lastname: Lara
authors.forename: Arvind
authors.initials: A
authors.lastname: Chappa
authors.forename: Amber R
authors.initials: AR
authors.lastname: Tink
authors.forename: Lincoln V
authors.initials: LV
authors.lastname: Johnson
authors.forename: Michelle
authors.initials: M
authors.lastname: Staples
mesh_terms: D017209:Apoptosis / Q000502:physiology; D002154:Calpain / Q000235:genetics / Q000378:metabolism; D053143:Caspase 2; D020169:Caspases / Q000235:genetics / Q000378:metabolism; D002460:Cell Line; D015536:Down-Regulation; D005136:Eye Proteins; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation / Q000187:drug effects / Q000502:physiology; D006801:Humans; D048369:MAP Kinase Kinase 1; D020929:Mitogen-Activated Protein Kinase Kinases / Q000235:genetics / Q000378:metabolism; D018919:Neovascularization, Physiologic / Q000502:physiology; D009414:Nerve Growth Factors; D018696:Neuroprotective Agents / Q000378:metabolism* / Q000494:pharmacology; D011506:Proteins / Q000378:metabolism* / Q000494:pharmacology / Q000502:physiology; D012160:Retina / Q000187:drug effects / Q000378:metabolism*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D015843:Serpins / Q000378:metabolism* / Q000494:pharmacology / Q000502:physiology; D040321:Vascular Endothelial Growth Factor Receptor-3 / Q000235:genetics / Q000378:metabolism; D000099174:Pigment Epithelium-Derived Factor
chemical_list: D002154:Calpain; D053143:Caspase 2; D020169:Caspases; D005136:Eye Proteins; D048369:MAP Kinase Kinase 1; D020929:Mitogen-Activated Protein Kinase Kinases; D009414:Nerve Growth Factors; D018696:Neuroprotective Agents; D011506:Proteins; D015843:Serpins; D040321:Vascular Endothelial Growth Factor Receptor-3; D000099174:Pigment Epithelium-Derived Factor; C482125:MAP2K1 protein, human; C482127:Map2k1 protein, mouse; C484806:CAPN1 protein, human