title: Subintimal angioplasty in lower limb ischaemia.
abstract: Subintimal angioplasty has been suggested as a treatment option for occlusive disease and has become an established practice in some centres, reducing their operative workload considerably. Others have concerns about the safety and durability of the procedure. This review will focus on the evidence for the use of subintimal angioplasty in lower limb occlusive disease. A systematic review of the literature from a Medline search has been carried out. Despite a paucity of trial data, subintimal angioplasty is now an established technique for the treatment of lower limb occlusive disease. The results for femoro-popliteal disease are well documented, with excellent technical and clinical success rates and low complication rates. The results for iliac disease are less well documented and demand caution. For infra-popliteal disease with critical ischaemia, the technique is again safe with good short and long-term results in a group of patients in whom distal bypass surgery is often risky. Subintimal angioplasty has a definite learning curve and those wishing to take it up should visit an experienced centre first. To achieve widespread acceptance it is likely to require large scale randomised controlled trials.
authors.affiliation: Department of Vascular and Endovascular Surgery, Leicester Royal Infirmary, Leicester, UK. ianloftus@aol.com
authors.forename: I M
authors.initials: IM
authors.lastname: Loftus
authors.forename: P D
authors.initials: PD
authors.lastname: Hayes
authors.forename: P R F
authors.initials: PR
authors.lastname: Bell
mesh_terms: D000368:Aged; D000792:Angiography; D000800:Angioplasty, Balloon / Q000379:methods*; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D005263:Femoral Artery; D006801:Humans; D007083:Iliac Artery; D007511:Ischemia / Q000000981:diagnostic imaging / Q000628:therapy*; D035002:Lower Extremity; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000000981:diagnostic imaging / Q000628:therapy; D011150:Popliteal Artery; D011379:Prognosis; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome; D017539:Tunica Intima / Q000601:surgery; D014654:Vascular Patency