Mycoplasma pneumoniae infection presenting as neutropenia, thrombocytopenia, and acute hepatitis in a child.
Extrapulmonary manifestations of Mycoplasma pneumoniae pneumonia are uncommon and include hematologic, gastrointestinal, musculoskeletal, dermatologic, and neurologic complications. We report a case of serologically-confirmed M. pneumoniae infection complicated by severe neutropenia, thrombocytopenia, and hepatitis. The presence of antiplatelet and antineutrophil antibodies suggested that these autoantibodies caused the cytopenias. The disease had an acute course and the patient recovered after steroid treatment. This case indicates that neutropenia, thrombocytopenia and hepatitis are possible clinical manifestations of M. pneumoniae infection.
Chen
Chun-Jung
CJ
Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, No. 325 Cheng-Kung Road, Section 2, Neihu, Taipei, Taiwan 114, ROC.
Juan
Chun-Jung
CJ
Hsu
Mu-Ling
ML
Lai
Yuan-Sheng
YS
Lin
Shih-Peng
SP
Cheng
Shin-Nan
SN
D000907:Antibodies, Bacterial / Q000097:blood; D001323:Autoantibodies / Q000097:blood; D002675:Child, Preschool; D005260:Female; D006505:Hepatitis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D009177:Mycoplasma pneumoniae / Q000276:immunology / Q000302:isolation & purification; D009503:Neutropenia / Q000209:etiology*; D011019:Pneumonia, Mycoplasma / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D012698:Serologic Tests; D013921:Thrombocytopenia / Q000209:etiology*
D000907:Antibodies, Bacterial; D001323:Autoantibodies