title: Cytotoxic natural products from Formosan plants and marine organisms.
abstract: Cytotoxic natural products isolated from Formosan plants and marine organisms till December, 2002, by local scientists or Taiwanese researchers have been reviewed. A total of about 200 compounds belonging to six types of chemical structures are listed or/and described in this article. Several compounds with special or selective activity have been described in more details. Some structure-activity relationships for the compounds of the same skeleton are drawn to clarify the possible pharmacophores.
authors.affiliation: School of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan, Republic of China. shoeilee@ha.mc.ntu.edu.tw
authors.forename: Shoei-Sheng
authors.initials: SS
authors.lastname: Lee
authors.forename: Wen-Liang
authors.initials: WL
authors.lastname: Chang
mesh_terms: D000818:Animals; D001688:Biological Products / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D002460:Cell Line; D003603:Cytotoxins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008386:Marine Biology; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry* / Q000145:classification; D013329:Structure-Activity Relationship; D013624:Taiwan; D013997:Time Factors
chemical_list: D001688:Biological Products; D003603:Cytotoxins