Modification of carbohydrate compositions of 31/36 kDa proteins of plerocercoids (sparganum) of Spirometra mansoni grown in different intermediate hosts.
We purified specific 31/36 kDa antigenic molecules from sparganum in different intermediate hosts (snakes and mice) and analyzed their monosaccharide compositions. Compositional analysis showed that glucose and mannose concentrations were 2-3 fold higher in the 31/36 kDa molecule purified from snakes than those from mice. This result implies that antigenic glycoproteins of sparganum from snakes might be modified in mammalian sparganosis with respect to their carbohydrate composition.
Yang
Hyun Jong
HJ
Department of Parasitology, College of Medicine, Ewha Womans University, Seoul 158-710, Korea. parayang@ewha.ac.kr
D000818:Animals; D000947:Antigens, Helminth / Q000737:chemistry*; D006801:Humans; D051379:Mice; D009005:Monosaccharides / Q000032:analysis*; D012911:Snakes / Q000469:parasitology; D013032:Sparganum / Q000276:immunology; D013146:Spirometra / Q000276:immunology*
D000947:Antigens, Helminth; D009005:Monosaccharides