HIV-1 cord-blood seroprevalence of parturient women in Sihanoukville, Cambodia.
Facing a 1.2% HIV-1 seroprevalence amongst its adult female population, Cambodia recently established national guidelines for the expansion of services to prevent mother-to-child transmission. Anticipating this expansion, Sihanoukville Hospital performed an anonymous HIV-1 cord-blood serosurvey of 600 consecutive deliveries from May 2001 through June 2002. Laboratory analysis utilizing ELISA and Western blot techniques yielded a 4.2% seroprevalence; a value resembling previous reports from other Sihanoukville antenatal clinics (3.9%) but exceeding the national ANC clinic average of 2.3%. Demographic information was confidentially collected and analysed for co-variation to HIV-1 status. One hundred percent of HIV positive mothers (P =0.013) self-reported the occupation of housewife, consistent with previous documentations suggesting the shift in infection burden from high-risk groups into the general female population. A substantial proportion received no prenatal care, suggesting that interventions addressing mother-to-child transmission will need to prepare for the management of pregnant women presenting at or near the time of delivery.
Theng
T
T
Departments of Obstetrics and Pediatrics, Sihanoukville Hospital, Sihanoukville, Cambodia.
Sok
P
P
Pugatch
D
D
Harwell
J I
JI
Rufner
K M
KM
Chhi Mean
V
V
Mayer
K H
KH
Cu-Uvin
S
S
D000328:Adult; D015153:Blotting, Western; D002160:Cambodia / Q000453:epidemiology; D005260:Female; D005312:Fetal Blood / Q000821:virology*; D015528:HIV Seroprevalence; D015497:HIV-1; D006801:Humans; D007231:Infant, Newborn; D015997:Neonatal Screening; D009790:Occupations; D036801:Parturition