[Exploring the effect of aspirin on primary hemostasis through bleeding time. Study of 16 volunteers].
Strong anti-binding platelets, aspirin is used in the treatment or the prevention of many thrombotic pathologies. We wanted to study the effect of aspirin over the bleeding time of a group of volunteers. It consisted of 16 volunteers aged from 20 to 25 years and having no haemorrhagic or thrombotic antecedent. For each of them, we have carried out a blood count by means of an automaton Sysmex K800, followed by a measure of the bleeding time (BT). Immediately after, each volunteer has ingested 250 mg of Aspegic; then, the BT has been measured every 24 hours and up to the fifth day. The BT has been carried out by means of IVY technique 3 points, that besides the time, allows to measure the volume of bleeding (microliter). All the check-ups were normal, however, the time and volumes of bleeding were respective by short and weak. After having taken aspirin, the bleeding time has significantly become longer to day 1 and day 2 (respectively 48% and 31.5% with regard to day 0) and the volume has increased to day 1, day 2 and day 3 (respectively 122.6%, 74.7% and 38.1% with regard to day 0).
Gargouri
Jalel
J
Mnif
Hela
H
Sellami
Samia
S
Rekik
Hayet
H
D000328:Adult; D001241:Aspirin / Q000494:pharmacology*; D001760:Bleeding Time; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*
D010975:Platelet Aggregation Inhibitors; D001241:Aspirin