title: The multiparametric scanning system for evaluation of minimal residual disease in hematological malignancies.
abstract: Combined simultaneous analysis of morphology, immunophenotyping and fluorescence in situ hybridization on the same cell offers advantages that may help to disclose the relevance of minimal residual disease (MRD) detection. Morphological analysis of small populations of cells related either to malignancy or recipient-associated markers may improve the accuracy of chimerism and MRD testing and delineate their clinical significance.
authors.affiliation: Department of Pediatric Hematology-Oncology, Safra Children's Hospital and Institute of Hematology, The Chaim Sheba Medical Center, Tel Hashomer, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. l-tracht@sheba.health.gov.il
authors.forename: Luba
authors.initials: L
authors.lastname: Trakhtenbrot
authors.forename: Gideon
authors.initials: G
authors.lastname: Rechavi
authors.forename: Ninette
authors.initials: N
authors.lastname: Amariglio
mesh_terms: D048429:Cell Size; D003581:Cytodiagnosis / Q000379:methods*; D019337:Hematologic Neoplasms / Q000175:diagnosis / Q000473:pathology*; D006651:Histocytochemistry; D006801:Humans; D016130:Immunophenotyping; D017404:In Situ Hybridization, Fluorescence; D018365:Neoplasm, Residual / Q000175:diagnosis / Q000473:pathology