title: Beta-globin gene cluster haplotypes linked to the betaS gene in western India.
abstract: The present survey, which involves 70 sickle cell anemia patients from Gujarat and Maharashtra revealed a high prevalence of the typical Arab-Indian haplotype (91.5 %). Six atypical haplotypes, including a Cameroon one were also found. Correlation of these various haplotypes with HbF expression was studied.
authors.affiliation: Institute of Immunohaematology (ICMR), King Edward Memorial Hospital Campus, Parel, Mumbai, India.
authors.forename: Malay B
authors.initials: MB
authors.lastname: Mukherjee
authors.forename: Reema R
authors.initials: RR
authors.lastname: Surve
authors.forename: Raman R
authors.initials: RR
authors.lastname: Gangakhedkar
authors.forename: Kanjaksha
authors.initials: K
authors.lastname: Ghosh
authors.forename: Roshan B
authors.initials: RB
authors.lastname: Colah
authors.forename: Dipika
authors.initials: D
authors.lastname: Mohanty
mesh_terms: D000755:Anemia, Sickle Cell / Q000453:epidemiology* / Q000235:genetics*; D004252:DNA Mutational Analysis; D005260:Female; D005914:Globins / Q000235:genetics*; D006239:Haplotypes / Q000235:genetics*; D006451:Hemoglobin, Sickle; D006801:Humans; D007194:India / Q000453:epidemiology*; D008297:Male; D005810:Multigene Family / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D006451:Hemoglobin, Sickle; D005914:Globins