IgA monoclonal gammopathy of undetermined significance with peripheral neuropathy.
Monoclonal gammopathy of undetermined significance (MGUS) and peripheral neuropathy may be causally linked. In most cases, the M-protein is of IgG or IgM type. Peripheral neuropathy associated with IgA MGUS is uncommon, and there are limited reports. Here, we report a case of a 55-year-old male who was diagnosed to have symmetrical sensorimotor peripheral neuropathy associated with IgA MGUS with deposits of IgA-monoclonal protein in the myelin sheath.
Mehndiratta
M M
MM
Department of Neurology, G.B. Pant Hospital, New Delhi 110002, India. mmehndi@vsnl.com
Sen
K
K
Tatke
M
M
Bajaj
B K
BK
D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000473:pathology; D009431:Neural Conduction; D010265:Paraproteinemias / Q000150:complications*; D010523:Peripheral Nervous System Diseases / Q000097:blood / Q000276:immunology*; D011930:Reaction Time
D007070:Immunoglobulin A; D007075:Immunoglobulin M