title: [Analysis of the efficiency of transcervical resection of endometrium for treating dysfunctional uterine bleeding and factors reducing the efficiency of the operation].
abstract: OBJECTIVE
  To investigate the efficiency and factors related to the recurrence of transcervical resection of endometrium (TCRE) in treating women with dysfunctional uterine bleeding (DUB).
  
  
  METHODS
  Two hundred and twenty women with DUB were selected for TCRE. Specimens from removed endometrium were obtained during the procedures and their menstruation and menorrhagia after the operations were followed up. We also studied the uterine specimens obtained from the recurrent cases undergoing hysterectomies. The specimens were stained by hematoxylin-eosin and immuno-histochemistry respectively to evaluate the depth of removed myometrium and the histopathologic changes in relapsed cases.
  
  
  RESULTS
  The follow up period after operation was 24 to 114 months. (1) Overall effective rate was 94.5%, in which amenorrhea rate was 25.9%, menstruation reduction rate was 68.6%. (2) The effective rate of corrective anemia was 97.3% and the satisfaction rate for the operation was 92.3%. (3) Thirty-eight cases required subsequent treatment as a result of recurrence, of which 10 cases underwent hysterectomy and 3 cases underwent repeat TCRE and 25 cases were given medicine treatment. (4) The average depth of myometrium in removed endometrium strip was 2.12 approximately 3.26 mm. (5) Endometrium regrowth was seen in the resected uterine specimens from relapsed cases and adenomyosis was also found in the intra-uterine wall in some cases.
  
  
  CONCLUSIONS
  (1) TCRE is a safe and effective alternative treatment for DUB. (2) The main factor reducing the efficiency is either incomplete removal of endometrium or adenomyosis. (3) Standardizing the procedures and strengthening postoperative management are essential requirements for improving the efficiency of TCRE.
authors.affiliation: Hysteroscopic Center, Fuxing Hospital, Capital University of Medical Sciences, Beijing 100038, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Duan
authors.forename: En-lan
authors.initials: EL
authors.lastname: Xia
authors.forename: Dan
authors.initials: D
authors.lastname: Yu
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhao
authors.forename: Jie
authors.initials: J
authors.lastname: Zheng
authors.forename: Jiu-mei
authors.initials: JM
authors.lastname: Cheng
authors.forename: Xue-bing
authors.initials: XB
authors.lastname: Peng
mesh_terms: D000328:Adult; D004598:Electrosurgery; D004717:Endometrium / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015907:Hysteroscopy / Q000379:methods; D008599:Menstruation Disturbances / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control; D011379:Prognosis; D016896:Treatment Outcome; D014592:Uterine Hemorrhage / Q000473:pathology / Q000601:surgery*