[Clinical effects of preoperative chemotherapy for Wilms tumor].
OBJECTIVE
To evaluate the effects of preoperative chemotherapy for Wilms' tumor.


METHODS
Thirty-five surgically treated cases of Wilms tumor were retrospectively analyzed, 27 of which received preoperative chemotherapy.


RESULTS
After chemotherapy, the tumor volume reduced obviously in 17 cases and adverse effects of the chemotherapeutic agents occurred in 15 cases. Subsequent operation was performed in all the patients, of whom 1 died during the operation, 4 had delayed healing of the incisions and 5 still had decreased leucocytes.


CONCLUSIONS
Chemotherapy before the operation for Wilms tumor can effectively reduce the complications of the operation. Appropriate chemotherapy protocol and vigorous conservative drug therapy help prevent the occurrence of adverse effects and complications of the chemotherapy.
Zhao
Yong-bin
YB
Department of Urology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
Zheng
Shao-bin
SB
Mao
Xiang-ming
XM
Zhou
Hai-kuan
HK
Zhang
Peng
P
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009396:Wilms Tumor / Q000628:therapy*