Outbreak of infection with hepatitis A virus (HAV) associated with a foodhandler and confirmed by sequence analysis reveals a new HAV genotype IB variant.
An outbreak of infection with hepatitis A virus associated with a foodhandler and involving 26 subjects occurred in Southern Italy. Sequence analysis of the VP3-VP1 and VP1-P2A junctions confirmed that the outbreak was due to a point source and allowed the identification of a new genotype IB variant. This report confirms the usefulness of sequence-based molecular fingerprinting during outbreaks.
Chironna
Maria
M
Hygiene Section, Department of Internal Medicine and Public Health, University of Bari, Policlinico Piazza G, Cesare 11, 70124 Bari, Italy. m.chironna@igiene.uniba.it
Lopalco
Pierluigi
P
Prato
Rosa
R
Germinario
Cinzia
C
Barbuti
Salvatore
S
Quarto
Michele
M
D000595:Amino Acid Sequence; D016022:Case-Control Studies; D004196:Disease Outbreaks; D005511:Food Handling; D005838:Genotype; D006506:Hepatitis A / Q000453:epidemiology* / Q000209:etiology / Q000821:virology; D030041:Hepatitis A virus / Q000145:classification* / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D017422:Sequence Analysis, DNA