Evaluation of a new particle gel immunoassay for determination of antibodies against Treponema pallidum.
A new particle gel immunoassay (DiaMed AG, Cressier sur Morat, Switzerland) with three recombinant Treponema pallidum antigens was evaluated with serum samples from patients with syphilis (n = 124) and patients without syphilis (n = 490). It proved to be a simple, rapid (20 min), and useful test with sensitivity, specificity, and positive and negative predictive values of 91.9, 99.8, 99.2, and 98%, respectively.
Schmidt
Bruno L
BL
Department of Dermatology, Hospital of the City of Vienna-Lainz, Wolkersbergenstr. 1, A-1130 Vienna, Austria. bruno.schmidt@kavwien.at
D000907:Antibodies, Bacterial / Q000097:blood*; D006801:Humans; D007118:Immunoassay; D011994:Recombinant Proteins / Q000276:immunology; D012680:Sensitivity and Specificity; D012698:Serologic Tests; D014210:Treponema pallidum / Q000276:immunology*
D000907:Antibodies, Bacterial; D011994:Recombinant Proteins