title: Benzothiazines in synthesis. Toward the synthesis of pseudopteroxazole.
abstract: [reaction: see text] The tricyclic benzothiazine 15 was prepared in a straightforward fashion via a completely stereoselective intramolecular Friedel-Crafts alkylation. This compound represents a potential precursor to the antitubercular agent, pseudopteroxazole. Its synthesis proceeded via a completely selective, intramolecular addition of a sulfoximine-stabilized carbanion to an alpha,beta-unsaturated ester, followed by functional group manipulations.
authors.affiliation: Department of Chemistry, University of Missouri-Columbia, Columbia, Missouri 65211, USA. harmatam@missouri.edu
authors.forename: Michael
authors.initials: M
authors.lastname: Harmata
authors.forename: Xuechuan
authors.initials: X
authors.lastname: Hong
authors.forename: Charles L
authors.initials: CL
authors.lastname: Barnes