title: Surgical management of special cases of intractable Meniere's disease: unilateral cases with intact canals and bilateral cases.
abstract: If a clinician seeks to allow patients with vertigo to return to work as soon as possible, it is very important to determine the appearance of vestibular symptoms during convalescence just after treatment, as well as the long-term results. Apprehensive patients with vertigo may undergo severe psychological torment if treatment requires long-term rest in bed before they can return to daily life. In this paper, we observed postoperative vestibular symptoms (subjective sensation and objective nystagmus) in 50 patients with intractable Meniere's disease, including cases from our previous preliminary report, during the period of convalescence just after endolymphatic sac drainage and steroid instillation surgery (EDSS). All symptoms were eliminated within 8 days after EDSS. There was no significant difference in the duration of any vestibular symptoms between bilateral (n = 8) and unilateral cases (n = 42). This result indicates that EDSS could be as safe a treatment for bilateral Meniere's disease as for unilateral disease. In unilateral cases with intact semicircular canal function (n = 17), postoperative evoked vestibular sensation, positional, and positioning (Dix-Hallpike) nystagmus disappeared significantly earlier than in those with canal paresis (n = 25). This result indicates that EDSS could keep the vestibular peripheral function of patients with unilateral Meniere's disease with intact canals quite stable after surgery. Therefore, EDSS could be recommended as an initial, less-invasive surgical treatment for intractable Meniere's disease, especially in unilateral cases with intact canals and in bilateral cases.
authors.affiliation: Department of Otolaryngology and Sensory Organ Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Tadashi
authors.initials: T
authors.lastname: Kitahara
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Kondoh
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Morihana
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Okumura
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Mishiro
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kubo
mesh_terms: D003907:Dexamethasone / Q000008:administration & dosage; D004322:Drainage; D004584:Electronystagmography; D004712:Endolymphatic Sac / Q000502:physiology; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007322:Instillation, Drug; D008575:Meniere Disease / Q000523:psychology / Q000601:surgery*; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage; D012665:Semicircular Canals / Q000502:physiology; D013997:Time Factors; D014724:Vestibular Function Tests
chemical_list: D005938:Glucocorticoids; D003907:Dexamethasone; D011239:Prednisolone