[Clinically analyzing the possible side-effects after injecting hydrophilic polyacrylamide gel as a soft-tissue filler].
OBJECTIVE
To evaluate the possible side-effects after injecting hydrophilic polyacrylamide gel for augmentation of the soft-tissue.


METHODS
Fifteen patients with some side-effects after injecting the hydrophilic polyacrylamide gel had been undergoing for the treatment in our unit from 2000 to 2001. Their symptoms were analyzed and the specimen of the tissue was also removed for pathologic examination.


RESULTS
The major complaints of the patients after injecting hydrophilic polyacrylamide gel were feeling pain(60.00%), uncomfortable (13.33%), no cosmetic improvement results (33.33%), secondary deformity (20.00%), long-lasting swelling (6.67%), and nodules (80.00%). The pathologic examination was showing the capsule formation (53.33%), macrophagocyte infiltration (60.00%) and granuloma producing (20.00%).


CONCLUSIONS
Clinical application of the hydrophilic polyacrylamide gel may result in some serious side-effects. It should be cautious to the physicians who may apply the product for clinic use.
Wang
You-bin
YB
Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Beijing 100041, China.
Huang
Jin-jing
JJ
Qiao
Qun
Q
Zhuang
Qiang
Q
Liu
Fu-hua
FH
D000180:Acrylic Resins / Q000009:adverse effects*; D000328:Adult; D001940:Breast / Q000187:drug effects / Q000473:pathology; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D013518:Surgery, Plastic / Q000009:adverse effects*
D000180:Acrylic Resins; C016680:polyacrylamide gels