title: Unexpected reductions of glycosyl spacer-armed phthalimides.
abstract: An unusual reductive ring-opening reaction in the title compounds, of the phthalimide group with sodium hydride in anhydrous DMF is observed for the first time and the presumed mechanism is described in detail. An unexpected hydrogenation of the phthalimide group was also observed.
authors.affiliation: Department of Chemical Biology, School of Pharmaceutical Sciences, National Research Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100083, China.
authors.forename: Xiang-Bao
authors.initials: XB
authors.lastname: Meng
authors.forename: Hui
authors.initials: H
authors.lastname: Li
authors.forename: Qing-Hua
authors.initials: QH
authors.lastname: Lou
authors.forename: Meng-Shen
authors.initials: MS
authors.lastname: Cai
authors.forename: Zhong-Jun
authors.initials: ZJ
authors.lastname: Li
mesh_terms: D000812:Anhydrides / Q000737:chemistry; D002240:Carbohydrate Sequence; D004126:Dimethylformamide / Q000737:chemistry; D006865:Hydrogenation; D010084:Oxidation-Reduction; D010797:Phthalimides / Q000737:chemistry*; D012964:Sodium / Q000737:chemistry
chemical_list: D000812:Anhydrides; D010797:Phthalimides; D004126:Dimethylformamide; D012964:Sodium