title: Multiple myeloma in a patient with fever of unknown origin and cholestasis.
abstract: The differential diagnosis of fever of unknown origin includes infectious diseases, malignancies and connective tissue diseases. Multiple myeloma is not usually included in the differential diagnosis, nor is it considered a frequent cause of cholestasis in the absence of amyloidosis. We report a case of multiple myeloma in a patient presenting with a long-standing fever and cholestasis. The patient underwent a long and unfruitful series of diagnostic procedures, including liver biopsy. The clue to the diagnosis, established with a marrow biopsy, was the presence of a paraprotein in the serum.
authors.affiliation: Department of Internal Medicine, Ospedale Civile, Livorno, Italy. nmumoli@tiscalinet.ca
authors.forename: Nicola
authors.initials: N
authors.lastname: Mumoli
authors.forename: Marco
authors.initials: M
authors.lastname: Cei
authors.forename: Roberto
authors.initials: R
authors.lastname: Incensati
authors.forename: Serena
authors.initials: S
authors.lastname: Verzuri
mesh_terms: D002779:Cholestasis / Q000209:etiology*; D005335:Fever of Unknown Origin / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis*