title: p53-mediated transcriptional activation: from test tube to cell.
abstract: Posttranslational modifications of histones have been strongly correlated with transcriptional regulation. In this issue of Cell, comprehensively examined the nature of arginine methyltransferases and histone modifications in p53-mediated transcription.
authors.affiliation: Department of Biochemistry, Purdue University, 175 South University Street, West Lafayette, IN 47907, USA.
authors.forename: Ian M
authors.initials: IM
authors.lastname: Fingerman
authors.forename: Scott D
authors.initials: SD
authors.lastname: Briggs
mesh_terms: D000818:Animals; D005809:Genes, Regulator / Q000235:genetics*; D006657:Histones / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D011499:Protein Processing, Post-Translational / Q000235:genetics; D011484:Protein-Arginine N-Methyltransferases / Q000235:genetics / Q000378:metabolism*; D015533:Transcriptional Activation / Q000235:genetics / Q000502:physiology*; D016159:Tumor Suppressor Protein p53 / Q000235:genetics* / Q000378:metabolism*
chemical_list: D006657:Histones; D016159:Tumor Suppressor Protein p53; D011484:Protein-Arginine N-Methyltransferases; C119966:coactivator-associated arginine methyltransferase 1