Reversible orofacial dyskinesia after ofloxacin treatment.
We report on a patient who developed orofacial dyskinesia 3 days after starting ofloxacin treatment. The association of orofacial dyskinesia with other fluoroquinolone antibiotics has been reported rarely, chiefly in the elderly with impaired renal or hepatic function or in overdosed patients. It has been ascribed to interference with GABA-ergic neurotransmission.
De Bleecker
Jan L
JL
Department of Neurology, Gent University Hospital, Ghent, Belgium. ja.debleeker@ugent.be
Vervaet
Veerle L
VL
De Sarro
Angela
A
D000328:Adult; D000890:Anti-Infective Agents / Q000009:adverse effects* / Q000627:therapeutic use; D000978:Antiparkinson Agents / Q000627:therapeutic use; D001712:Biperiden / Q000627:therapeutic use; D004409:Dyskinesia, Drug-Induced / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D012141:Respiratory Tract Infections / Q000188:drug therapy
D000890:Anti-Infective Agents; D000978:Antiparkinson Agents; D001712:Biperiden