Palladium catalyzed amination of vinyl chlorides: a new entry to imines, enamines and 2-amino-1,3-butadienes.
Vinyl chlorides are employed for the first time in palladium catalyzed cross-coupling reactions with amines to furnish imines and enamines. The new methodology has been applied to the synthesis of 2-amino-1,3-butadienes, that could not be achieved from the corresponding bromides.
Barluenga
Jose
J
Instituto Universitario de Quimica Organometalica "Enrique Moles", Universidad de Oviedo, Oviedo, 33071, Spain. Barluenga@uniovi.es
Fernandez
M Alejandro
MA
Aznar
Fernando
F
Valdes
Carlos
C