title: Techniques for high-throughput characterization of peptides, oligonucleotides and catalysis efficiency.
abstract: Combinatorial processes have been widely applied to many disciplines in chemistry and biology. The vast numbers of unique entities generated by combinatorial synthesis have led to the development of high-throughput methods for characterizing samples, to avoid bottlenecks created by the application of conventional, serial-based analytical techniques. In recent years, high-throughput and novel methods utilizing mass spectrometry, multiplexed capillary electrophoresis, various forms of optical detection, and even sound waves have been investigated for a variety of applications.
authors.affiliation: CombiSep, Inc., 2711 South Loop Drive, Ames, Iowa 50010, USA.
authors.forename: Jeremy R
authors.initials: JR
authors.lastname: Kenseth
authors.forename: Yan
authors.initials: Y
authors.lastname: He
authors.forename: Dennis
authors.initials: D
authors.lastname: Tallman
authors.forename: Ho-ming
authors.initials: HM
authors.lastname: Pang
authors.forename: Shelley J
authors.initials: SJ
authors.lastname: Coldiron
mesh_terms: D002384:Catalysis; D020650:Combinatorial Chemistry Techniques / Q000379:methods* / Q000639:trends; D015195:Drug Design; D019075:Electrophoresis, Capillary; D013058:Mass Spectrometry; D008422:Materials Testing; D009841:Oligonucleotides / Q000737:chemistry*; D055095:Optics and Photonics / Q000295:instrumentation; D010455:Peptides / Q000737:chemistry*
chemical_list: D009841:Oligonucleotides; D010455:Peptides