SimplePHOX, a readily available chiral ligand system for iridium-catalyzed asymmetric hydrogenation.
[reaction: see text] New Ir-SimplePHOX complexes Ir-6-Ir-9 catalyze the quantitative, highly enantioselective hydrogenation of a range of unfunctionalized and functionalized olefins. Synthesis, catalytic results, and X-ray crystal structures are presented here.
Smidt
Sebastian P
SP
Department of Chemistry, University of Basel, St. Johanns-Ring 19, CH-4056 Basel, Switzerland.
Menges
Frederik
F
Pfaltz
Andreas
A
D002384:Catalysis; D006865:Hydrogenation; D007495:Iridium / Q000737:chemistry*; D008024:Ligands; D008956:Models, Chemical; D008968:Molecular Conformation; D010080:Oxazoles / Q000138:chemical synthesis*; D013237:Stereoisomerism
D008024:Ligands; D010080:Oxazoles; D007495:Iridium