Subconjunctival antibiotics for acute postcataract extraction endophthalmitis--is it necessary?
OBJECTIVE
To evaluate the efficacy of adjunctive subconjunctival antibiotic injection in the treatment of acute postcataract extraction endophthalmitis.


METHODS
Retrospective cohort study.


METHODS
Patients who presented with hand motions or better vision and received subconjunctival antibiotics (SC+ group) were compared with those who did not (SC- group) in the treatment of acute postoperative endophthalmitis.


RESULTS
The rate of obtaining a final vision of 20/40 or better was 60% in the SC+ group (n = 25) compared with 72% in the SC- group (n = 18) (P =.69), and the mean change in logMAR was -1.36 (improvement) versus -1.34 (P =.93). Based on a linear regression model controlling for presenting vision, there was no statistical difference in the mean logMAR change between the two groups (P =.73).


CONCLUSIONS
Subconjunctival antibiotic injection as an adjunct to intravitreal antibiotics was unassociated with treatment benefit in patients with acute postoperative endophthalmitis presenting with vision of hand motions or better.
Iyer
Mohan N
MN
Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, 53226, USA.
Han
Dennis P
DP
Yun
Hyun J
HJ
Eastwood
Dan
D
Kim
Judy E
JE
Connor
Thomas B
TB
Wirostko
William J
WJ
Dev
Sundeep
S
D000208:Acute Disease; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002387:Cataract Extraction; D017024:Chemotherapy, Adjuvant; D015331:Cohort Studies; D003228:Conjunctiva / Q000187:drug effects*; D009877:Endophthalmitis / Q000188:drug therapy* / Q000382:microbiology; D015818:Eye Infections, Bacterial / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D007267:Injections; D011183:Postoperative Complications / Q000188:drug therapy* / Q000382:microbiology; D012189:Retrospective Studies; D014822:Vitreous Body / Q000187:drug effects
D000900:Anti-Bacterial Agents