title: Mycoplasma pneumoniae infection presenting as neutropenia, thrombocytopenia, and acute hepatitis in a child.
abstract: Extrapulmonary manifestations of Mycoplasma pneumoniae pneumonia are uncommon and include hematologic, gastrointestinal, musculoskeletal, dermatologic, and neurologic complications. We report a case of serologically-confirmed M. pneumoniae infection complicated by severe neutropenia, thrombocytopenia, and hepatitis. The presence of antiplatelet and antineutrophil antibodies suggested that these autoantibodies caused the cytopenias. The disease had an acute course and the patient recovered after steroid treatment. This case indicates that neutropenia, thrombocytopenia and hepatitis are possible clinical manifestations of M. pneumoniae infection.
authors.affiliation: Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, No. 325 Cheng-Kung Road, Section 2, Neihu, Taipei, Taiwan 114, ROC.
authors.forename: Chun-Jung
authors.initials: CJ
authors.lastname: Chen
authors.forename: Chun-Jung
authors.initials: CJ
authors.lastname: Juan
authors.forename: Mu-Ling
authors.initials: ML
authors.lastname: Hsu
authors.forename: Yuan-Sheng
authors.initials: YS
authors.lastname: Lai
authors.forename: Shih-Peng
authors.initials: SP
authors.lastname: Lin
authors.forename: Shin-Nan
authors.initials: SN
authors.lastname: Cheng
mesh_terms: D000907:Antibodies, Bacterial / Q000097:blood; D001323:Autoantibodies / Q000097:blood; D002675:Child, Preschool; D005260:Female; D006505:Hepatitis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D009177:Mycoplasma pneumoniae / Q000276:immunology / Q000302:isolation & purification; D009503:Neutropenia / Q000209:etiology*; D011019:Pneumonia, Mycoplasma / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D012698:Serologic Tests; D013921:Thrombocytopenia / Q000209:etiology*
chemical_list: D000907:Antibodies, Bacterial; D001323:Autoantibodies