title: Langerhans' cell histiocytosis of the temporal lobe and pons.
abstract: Intracerebral Langerhans' cell histiocytosis (LCH) is rare and tends to involve the hypothalamus. The authors report a rare case of LCH in the temporal lobe that subsequently was followed by a brainstem lesion. This appears to be the first case of temporal lobe and brainstem LCH that has been treated successfully and published. A 24-year-old man complained of cacosmia and nausea with a slight headache. He had a left temporal LCH, which was removed completely, but developed a brainstem lesion a year later. The pontine LCH was treated with radiosurgery. The follow-up period was 4 years without any neurological or radiological symptoms or signs. The 12 cases of solitary intracranial non-hypothalamic LCH reported previously are reviewed. Gamma knife radiosurgery effectively controlled the local growth of the pontine LCH without adverse effect.
authors.affiliation: Department of Neurosurgery, Ege University Faculty of Medicine, Bornova, Izmir, Turkey. caglis@med.ege.edu.tr
authors.forename: S
authors.initials: S
authors.lastname: Cagli
authors.forename: N
authors.initials: N
authors.lastname: Oktar
authors.forename: E
authors.initials: E
authors.lastname: Demirtas
mesh_terms: D000328:Adult; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011149:Pons / Q000473:pathology / Q000601:surgery*; D016634:Radiosurgery; D013702:Temporal Lobe / Q000473:pathology / Q000601:surgery*