title: Hypopyon uveitis and relapsing polychondritis: a report of 2 patients and review of autoimmune hypopyon uveitis.
abstract: OBJECTIVE
  To report hypopyon uveitis as an ophthalmic finding associated with relapsing polychondritis.
  
  
  METHODS
  Interventional case reports.
  
  
  METHODS
  Two patients with hypopyon uveitis as a manifestation of relapsing polychondritis.
  
  
  METHODS
  Complete ocular and systemic examinations as well as chart reviews were performed for 2 patients with hypopyon uveitis as a manifestation of relapsing polychondritis at presentation.
  
  
  METHODS
  Clinical observation and response to treatment in 2 patients with hypopyon uveitis secondary to relapsing polychondritis.
  
  
  RESULTS
  A 70-year-old white male had unilateral hypopyon uveitis accompanied by a migratory polyarthralgia at presentation. Fifteen months later, he sought treatment for chondritis of the right auricle and was diagnosed with relapsing polychondritis. A 42-year-old white female with known relapsing polychondritis had bilateral hypopyon uveitis at presentation during a systemic relapse. Both patients had resolution of the hypopyon with topical and systemic steroids.
  
  
  CONCLUSIONS
  Relapsing polychondritis should be considered in the differential diagnosis of sterile hypopyon uveitis. Steroids and systemic immunosuppression can be used to treat the uveitis.
authors.affiliation: Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
authors.forename: Nicholas G
authors.initials: NG
authors.lastname: Anderson
authors.forename: Enrique
authors.initials: E
authors.lastname: Garcia-Valenzuela
authors.forename: Daniel F
authors.initials: DF
authors.lastname: Martin
mesh_terms: D000328:Adult; D000368:Aged; D018771:Arthralgia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D003937:Diagnosis, Differential; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011081:Polychondritis, Relapsing / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D015423:Scleritis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D013492:Suppuration / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D014606:Uveitis, Anterior / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
chemical_list: D005938:Glucocorticoids