[Effect of external gamma-irradiation on the genetic apparatus of somatic cells of rat fetus].
Cytogenetic effects of different radiation dose rate and dose value were studied in fibroblasts of 20-day old rat fetuses and new-born ratlings. Quantitative and qualitative changes in the occurrence frequency in the spectrum of chromosome aberration types were revealed and changes in aneuploid fibroblast ratio were observed. The damages in the fibroblast chromosome structure of fetuses remain after birth (2-day-old ratling) and they were also observed in fetuses of the second generation.
Nikolaevich
L N
LN
Institute of Radiobiology, National Academy of Sciences of Belarus, Minsk, 220141 Belarus. nikolaevich@radbio.bas-net.by
Amvros'ev
A P
AP
D000782:Aneuploidy; D000818:Animals; D000831:Animals, Newborn; D002869:Chromosome Aberrations; D004307:Dose-Response Relationship, Radiation; D005333:Fetus / Q000166:cytology / Q000528:radiation effects*; D005347:Fibroblasts / Q000528:radiation effects* / Q000648:ultrastructure; D005720:Gamma Rays; D051381:Rats