Recurrent tendinitis after treatment with two different fluoroquinolones.
Tendinopathies with and without tendon rupture are rare adverse events, occurring mainly following older fluoroquinolones, but recently also to an increasing extent following levofloxacin. We report the first case of tendinitis after treatment with moxifloxacin, and of recurrent tendinitis after treatment with 2 different fluoroquinolones. From these findings we conclude hitherto unexplained class effect of fluoroquinolones in respect of the development of tendinitis.
Burkhardt
Olaf
O
Department of Pulmonary and Critical Care Medicine, University Otto-von-Guericke, Magdeburg, Germany. olaf.burkhardt@medizin.uni-magdeburg.de
Köhnlein
Thomas
T
Pap
Thomas
T
Welte
Tobias
T
D000125:Achilles Tendon / Q000000981:diagnostic imaging; D000368:Aged; D000890:Anti-Infective Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy; D001372:Aza Compounds / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D024841:Fluoroquinolones / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D064704:Levofloxacin; D000077266:Moxifloxacin; D015242:Ofloxacin / Q000009:adverse effects* / Q000627:therapeutic use; D011804:Quinolines / Q000009:adverse effects* / Q000627:therapeutic use; D012008:Recurrence; D052256:Tendinopathy / Q000139:chemically induced*; D014463:Ultrasonography
D000890:Anti-Infective Agents; D001372:Aza Compounds; D024841:Fluoroquinolones; D011804:Quinolines; D064704:Levofloxacin; D015242:Ofloxacin; D000077266:Moxifloxacin