5,10-methylenetetrahydrofolate reductase (MTHFR) 677C-->T and 1298A-->C mutations are associated with DNA hypomethylation.
Castro
R
R
Rivera
I
I
Ravasco
P
P
Camilo
M E
ME
Jakobs
C
C
Blom
H J
HJ
de Almeida
I T
IT
D000328:Adult; D000368:Aged; D004247:DNA / Q000235:genetics / Q000378:metabolism; D019175:DNA Methylation; D003845:Deoxycytosine Nucleotides / Q000378:metabolism; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics*; D008875:Middle Aged; D017354:Point Mutation; D012150:Polymorphism, Restriction Fragment Length; D020641:Polymorphism, Single Nucleotide; D011174:Portugal
D003845:Deoxycytosine Nucleotides; C024107:2'-deoxycytidine 5'-triphosphate; D004247:DNA; D042965:Methylenetetrahydrofolate Reductase (NADPH2)