Peroxisome membrane biogenesis: the stage is set.
Pex3p and Pex19p are key players in the post-translational import of peroxisomal membrane proteins. New data suggest that these peroxins act in tandem, Pex19p as a cytosolic chaperone and import receptor for peroxisomal membrane proteins, and Pex3p as docking factor at the peroxisomal membrane.
Schliebs
Wolfgang
W
Institut für Physiologische Chemie, Ruhr-Universität Bochum, 44780 Bochum, Germany. Wolfgang.Schliebs@rub.de
Kunau
Wolf-H
WH
D001692:Biological Transport; D007425:Intracellular Membranes / Q000378:metabolism*; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism*; D008954:Models, Biological; D018832:Molecular Chaperones / Q000235:genetics / Q000378:metabolism*; D000074401:Peroxins; D020675:Peroxisomes / Q000235:genetics* / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics / Q000378:metabolism*
D008565:Membrane Proteins; D018832:Molecular Chaperones; C070895:PEX3 protein, S cerevisiae; D000074401:Peroxins; D029701:Saccharomyces cerevisiae Proteins