Post-surgical scleritis associated with the ganciclovir implant.
Although the ganciclovir implant is an effective and well-tolerated treatment for cytomegalovirus retinitis in patients with human immunodeficiency virus infection, complications that may occur include retinal detachment, implant extrusion, and endophthalmitis. A 22-year-old woman with human immunodeficiency virus infection presented with a painful left eye with scleritis overlying previous ganciclovir implant sclerotomy sites. The inflammation progressed 360 degrees around the pars plana with progressive thinning at the implant sites. Post-surgical necrotizing scleritis is another complication that can occur in patients with ganciclovir implants.
Srivastava
Sunil
S
National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892-1863, USA.
Taylor
Perdita
P
Wood
Lauren V
LV
Lee
Susan S
SS
Robinson
Michael R
MR
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy; D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage*; D017726:Cytomegalovirus Retinitis / Q000188:drug therapy; D004343:Drug Implants / Q000009:adverse effects*; D005260:Female; D015774:Ganciclovir / Q000008:administration & dosage*; D006801:Humans; D011183:Postoperative Complications; D015423:Scleritis / Q000209:etiology*
D000998:Antiviral Agents; D004343:Drug Implants; D015774:Ganciclovir