Antibodies to dorsal root ganglia and olfactory cells in a patient with chronic sensory neuropathy and anosmia.
We report the case of a 51-year-old woman with anosmia and chronic sensory ataxic neuropathy. Olfactory tests suggested neurosensory anosmia. Immunocytochemical analysis showed serum antibodies against dorsal root ganglion (DRG) cells and olfactory neurons, in the absence of other known causes of anosmia and sensory neuropathy. Clinical and laboratory data suggested a slow autoimmune process affecting dorsal root ganglion and olfactory cells.
Gambelli
Simona
S
Department of Neurological and Behavioural Sciences, University of Siena, Viale Bracci 2, 53100 Siena, Italy.
Ginanneschi
Federica
F
Malandrini
Alessandro
A
Palmeri
Silvia
S
Berti
Gianna
G
Desiderio
Passali
P
Luisa
Bellussi
B
Maria
Passali Francesco
PF
Rossi
Alessandro
A
D000906:Antibodies / Q000097:blood*; D001259:Ataxia / Q000276:immunology; D005260:Female; D005727:Ganglia, Spinal / Q000276:immunology*; D006801:Humans; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000473:pathology; D000857:Olfaction Disorders / Q000150:complications / Q000276:immunology*; D009832:Olfactory Nerve / Q000276:immunology*; D011129:Polyradiculoneuropathy / Q000150:complications / Q000276:immunology*; D013497:Sural Nerve / Q000473:pathology
D000906:Antibodies