title: Focal epithelial hyperplasia (Heck's disease): report of two cases with PCR detection of human papillomavirus DNA.
abstract: Focal epithelial hyperplasia (FEH) (Heck's disease) is essentially a benign oral infection produced by the human papillomavirus (HPV). Although this condition is known to exist in numerous populations and ethnic groups, it is relatively rare in South-East Asia. The following report is based on two cases of adult FEH with histopathological features in favour of the disease. In addition, polymerase chain reaction was performed to detect the presence of HPV DNA in the lesions in order to confirm the histopathological diagnosis.
authors.affiliation: Department of Oral Pathology, Faculty of Dental Sciences, University of Peradeniya, Peradeniya, Sri Lanka.
authors.forename: P R
authors.initials: PR
authors.lastname: Jayasooriya
authors.forename: S
authors.initials: S
authors.lastname: Abeyratne
authors.forename: A W
authors.initials: AW
authors.lastname: Ranasinghe
authors.forename: W M
authors.initials: WM
authors.lastname: Tilakaratne
mesh_terms: D000328:Adult; D000368:Aged; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D017573:Focal Epithelial Hyperplasia / Q000473:pathology / Q000821:virology*; D006801:Humans; D008297:Male; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D013188:Sri Lanka
chemical_list: D004279:DNA, Viral