title: Effect of maternal exposure to tributyltin on reproduction of the pearl oyster (Pinctada fucata martensii).
abstract: We examined the effect of tributyltin (TBT) on reproduction of the pearl oyster (Pinctada fucata martensii). In a maternal exposure test, five female pearl oysters were exposed to TBT at measured concentrations of 0 (control), 0.092, or 0.191 microg/L at 25 degreesC for one week, and the embryo developmental success (the ratio of normal D-larvae to all larvae) was measured. The embryo developmental success was significantly decreased in the 0.191-microg/L treatment group (65.5%) compared to that in the control group (82.5%; p = 0.031). Concentrations of TBT in the ovary reached 0.088 microg/g in the 0.191-microg/L treatment group. In a waterborne exposure test, inseminated eggs were exposed to TBT at measured concentrations of 0 (control), 0.020, 0.045, 0.091, 0.192, or 0.374 microg/L for 24 h. The embryo developmental success also was significantly decreased in the 0.192-microg/L treatment group (78.3%; p = 0.020) and no development at all was observed in the 0.374-microg/L treatment group compared with that in the control group (95.4%). These results clearly demonstrate that TBT accumulating in the bodies of bivalves has the potential to inhibit reproduction.
authors.affiliation: Department of Bioscience and Biotechnology, Graduate School of Bioscience and Bioenvironmental Sciences, Kyushu University, Hakozaki 6-10-1, Higashi-ku, Fukuoka 812-8581, Japan.
authors.forename: Suguru
authors.initials: S
authors.lastname: Inoue
authors.forename: Yuji
authors.initials: Y
authors.lastname: Oshima
authors.forename: Kiyohito
authors.initials: K
authors.lastname: Nagai
authors.forename: Takashi
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Jyoji
authors.initials: J
authors.lastname: Go
authors.forename: Norihisa
authors.initials: N
authors.lastname: Kai
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Honjo
mesh_terms: D000818:Animals; D004064:Digestive System / Q000187:drug effects / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005260:Female; D007814:Larva / Q000187:drug effects / Q000502:physiology; D018811:Maternal Exposure; D010125:Ostreidae / Q000187:drug effects* / Q000196:embryology; D010053:Ovary / Q000187:drug effects / Q000378:metabolism; D012098:Reproduction / Q000187:drug effects* / Q000502:physiology; D014220:Trialkyltin Compounds / Q000633:toxicity*; D014873:Water Pollutants / Q000009:adverse effects*
chemical_list: D014220:Trialkyltin Compounds; D014873:Water Pollutants; C011559:tributyltin