Intralesional immunotherapy for warts using a combination of skin test antigens: a safe and effective therapy.
Warts are a common dermatologic problem. There are many treatments available. Intralesional injection of a skin test antigen has been shown to be efficacious at eradicating all warts when only a part of one wart is injected. The aim of this study was to determine whether injection of the combination of Candida albicans, mumps, and Trichophyton skin test antigens was more efficacious than and as safe as single antigen injection. Seventy-one percent of subjects had resolution of their warts with the injection of the combination of skin test antigens in this open label single arm study.
Johnson
Sandra Marchese
SM
Department of Dermatology, University of Arkansas for Medical Sciences, Central Arkansas Veterans Healthcare System, Department of Pediatrics, Arkansas Children's Hospital, USA. johnsonsandram@uams.edu
Horn
Thomas D
TD
D000328:Adult; D000946:Antigens, Fungal / Q000008:administration & dosage* / Q000276:immunology; D000956:Antigens, Viral / Q000008:administration & dosage* / Q000276:immunology; D002176:Candida albicans / Q000276:immunology; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D016233:Immunotherapy, Active; D015552:Injections, Intralesional; D008297:Male; D009109:Mumps virus / Q000276:immunology; D012882:Skin Tests; D016896:Treatment Outcome; D014249:Trichophyton / Q000276:immunology; D014860:Warts / Q000276:immunology / Q000628:therapy*
D000946:Antigens, Fungal; D000956:Antigens, Viral