title: The executive clock drawing task (CLOX) is a poor screening test for executive dysfunction in Chinese elderly patients with subcortical ischemic vascular disease.
abstract: Executive dysfunction (ED) is a prominent feature of subcortical ischemic vascular disease. A screening test for ED is lacking among Chinese. The objective of the study is to investigate the validity and reliability of a Chinese version of the Executive clock drawing task (CLOX) in screening ED among Chinese elderly patients with small subcortical infarct (SSI). The Chinese version of CLOX correlated with MMSE, CDRS I/P, and WCST perseverative errors. However, multivariate regression analysis showed that only education (R(2) change=0.22, p < 0.001 ) and MMSE (R(2) change=0.35, p < 0.001), but none of the standard executive function tests, significantly accounted for the variance in the CLOX. Test-retest (r=0.84) and inter-rater reliability (r=0.84) were high for the CLOX. Conclusions. Although the CLOX is reliable, it is not valid in detecting ED in Chinese elderly patients with SSI.
authors.affiliation: Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong.
authors.forename: Adrian
authors.initials: A
authors.lastname: Wong
authors.forename: Vincent C T
authors.initials: VC
authors.lastname: Mok
authors.forename: Patty
authors.initials: P
authors.lastname: Yim
authors.forename: Michael
authors.initials: M
authors.lastname: Fu
authors.forename: Wynnie W M
authors.initials: WW
authors.lastname: Lam
authors.forename: Carmen
authors.initials: C
authors.lastname: Yau
authors.forename: Agnes S
authors.initials: AS
authors.lastname: Chan
authors.forename: Ka Sing
authors.initials: KS
authors.lastname: Wong
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002681:China; D003072:Cognition Disorders / Q000209:etiology*; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D008403:Mass Screening; D008609:Mental Status Schedule / Q000706:statistics & numerical data; D008875:Middle Aged; D009483:Neuropsychological Tests; D011340:Problem Solving / Q000502:physiology*; D011594:Psychometrics; D012680:Sensitivity and Specificity; D014652:Vascular Diseases / Q000150:complications* / Q000175:diagnosis*