CD45RA+ and CD45RO+ lymphocyte subpopulations in patients with monoclonal gammopathies: correlations with diagnosis, clinical stage and treatment status.
Alterations in blood lymphocyte subsets may be involved in the development of overt myeloma. Naive (CD4+CD45RA+) and memory (CD4+CD45RO+) helper T-cell subsets are important effectors of immune T-cell regulation. We analyzed the distribution of these blood lymphocyte subpopulations in patients with monoclonal gammopathies, considering the type of disorder, clinical stage, and treatment status.
Raya Sánchez
José María
JM
Nieto
Luis Hernández
LH
Brito Barroso
María Luisa
ML
González Brito
Gloria
G
del Mar Caballero Gómez
María
M
D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D017493:Leukocyte Common Antigens / Q000032:analysis*; D016131:Lymphocyte Subsets / Q000473:pathology*; D008297:Male; D010265:Paraproteinemias / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy
D017493:Leukocyte Common Antigens