title: The level of nitric oxide in the cortex correlates well with brain lateralization.
abstract: The correlation between nitric oxide (NO) levels in the cortices and brain lateralization was investigated via the paw preference test in which three groups of mice (left-pawed, ambidextrous and right pawed) were selected. Results showed that the right cortices had higher NO levels than the left cortices for both normal and lipopolysaccharide-treated mice. There were significant differences in NO levels in the right/left cortices depending on the behavioral lateralization as expressed by paw preference. Finally, individual levels of NO in the right/left cortices correlated well with individual paw preference scores. The relationship was parabolic. The results suggest a strong relationship between NO asymmetries as well as the direction and the intensity of behavioral lateralization.
authors.affiliation: Department of Microbiology and Immunology, Shantou University Medical College, Shantou, Guangdong 515031, P.R. China.
authors.forename: Fu
authors.initials: F
authors.lastname: Qingling
authors.forename: Li
authors.initials: L
authors.lastname: Xin
authors.forename: Yan
authors.initials: Y
authors.lastname: Chaowu
authors.forename: Li
authors.initials: L
authors.lastname: Kangsheng
authors.forename: Liao
authors.initials: L
authors.lastname: Xiaoxing
mesh_terms: D000818:Animals; D001522:Behavior, Animal; D002540:Cerebral Cortex / Q000378:metabolism*; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D009569:Nitric Oxide / Q000378:metabolism*
chemical_list: D009569:Nitric Oxide