Oral delivery of medications to companion animals: palatability considerations.
There is an increased need for highly palatable solid oral dosage forms for companion animals, which are voluntarily accepted by the dog or cat, either from a feeding bowl or from the outstretched hand of the pet owner. Such dosage forms represent an emerging trend in companion animal formulations with major impact on medical needs such as convenience and compliance, particularly for chronically administered medications, and on marketing needs such as product differentiation. This review focuses on the science of taste, food and flavor preferences of dogs and cats, and palatability testing, in the context of applying these principles to the development of an oral palatable tablet for companion animals.
Thombre
Avinash G
AG
Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340, USA. Avinash_G_Thombre@groton.pfizer.com
D000284:Administration, Oral; D000821:Animal Feed; D000818:Animals; D002415:Cats / Q000033:anatomy & histology / Q000502:physiology*; D003692:Delayed-Action Preparations; D004285:Dogs / Q000033:anatomy & histology / Q000502:physiology*; D004339:Drug Compounding; D005421:Flavoring Agents; D005518:Food Preferences; D013045:Species Specificity; D013607:Tablets; D013649:Taste; D019155:Veterinary Drugs / Q000008:administration & dosage* / Q000737:chemistry
D003692:Delayed-Action Preparations; D005421:Flavoring Agents; D013607:Tablets; D019155:Veterinary Drugs