Combinatorial approaches to synthetic receptors.
Combinatorial chemistry can be efficiently used for the synthesis and evaluation of binding properties of libraries of synthetic receptors. This approach has been applied particularly to 'tweezer' and other 'multi-armed' receptors, and has been used for the identification of receptors for peptides in aqueous media, and for the development of new sensors and sensor arrays.
Srinivasan
Natarajan
N
School of Chemistry, University of Southampton, Southampton, SO17 1BJ, UK.
Kilburn
Jeremy D
JD
D001665:Binding Sites; D015374:Biosensing Techniques; D002626:Chemistry, Pharmaceutical; D020650:Combinatorial Chemistry Techniques; D015195:Drug Design; D015394:Molecular Structure; D019151:Peptide Library; D010455:Peptides / Q000737:chemistry / Q000378:metabolism; D011955:Receptors, Drug / Q000032:analysis / Q000737:chemistry* / Q000378:metabolism
D019151:Peptide Library; D010455:Peptides; D011955:Receptors, Drug