title: Long-term results of peripheral arterial disease rehabilitation.
abstract: OBJECTIVE
  Although the Peripheral Arterial Disease Rehabilitation Program (PADRx) improves walking ability and quality of life over brief periods of follow-up, the long-term durability of results has not been established. This study examined functional status, walking ability, and quality of life in patients several months after completion of a 12-week PADRx.
  
  
  METHODS
  Patients who completed a PADRx were eligible for participation. A Medical Outcomes Study 36-Item Short Form (SF-36), Walking Impairment Questionnaire (WIQ), and physical activity questionnaire were administered by telephone. A progressive treadmill test was performed on-site.
  
  
  RESULTS
  Of 63 eligible patients, 14 were lost to follow-up, 11 refused participation, and four died. Thirty-four patients had completed PADRx 20 to 80 months previously (mean, 48.2 +/- 13.7 months), and completed the phone survey. Fifteen patients reported exercising a minimum of 60 min/wk for 3 months (EX group), and 19 had not exercised in the preceding 3 months (SED group). Self-reported SF-36 values were significantly different between the EX and SED groups for Physical Function (43.3 +/- 8.2 vs 34.2 +/- 7.8), Role-Physical Function (41.2 +/- 7.7 vs 32.8 +/- 9.2), and Bodily Pain (46.9 +/- 8.8 vs 38.9 +/- 7.1), as well as the Physical Composite (43.5 +/- 6.5 vs 34.0 vs 5.8) domains of the SF-36. Similarly the WIQ demonstrated significant differences in Walking Distance (46.8 +/- 36.2 vs 7.8 +/- 9.4), Walking Speed (47.5 +/- 32.6 vs 14.5 +/- 13.9), and Stair Climbing (60.6 +/- 36.6 vs 37.1 +/- 27.6), favoring the EX group. Sixteen patients, equally distributed between the EX and SED groups, completed the progressive treadmill test. Both groups had experienced improvement (P <.05) in claudication pain time and maximal walking time after completing the 12-week supervised program. The EX group maintained increased claudication pain time of 121% and maximum walking time of 109% over baseline, whereas the SED group values had returned to baseline (P <.05).
  
  
  CONCLUSIONS
  Patients with claudication realize symptomatic and functional improvement with supervised exercise programs. Those who continue to exercise will potentially maintain these benefits and experience improved health-related quality of life.
authors.affiliation: Department of Physical Education and Exercise Science, University of Rhode Island, Kingston, RI, USA.
authors.forename: Julie R
authors.initials: JR
authors.lastname: Menard
authors.forename: Hadley E
authors.initials: HE
authors.lastname: Smith
authors.forename: Deborah
authors.initials: D
authors.lastname: Riebe
authors.forename: Christina M
authors.initials: CM
authors.lastname: Braun
authors.forename: Bryan
authors.initials: B
authors.lastname: Blissmer
authors.forename: Robert B
authors.initials: RB
authors.lastname: Patterson
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000842:Ankle / Q000098:blood supply* / Q000473:pathology / Q000503:physiopathology; D001794:Blood Pressure / Q000502:physiology; D001916:Brachial Artery / Q000473:pathology / Q000503:physiopathology; D018450:Disease Progression; D005080:Exercise Test; D005081:Exercise Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007383:Intermittent Claudication / Q000503:physiopathology / Q000534:rehabilitation; D008297:Male; D009043:Motor Activity / Q000502:physiology; D016491:Peripheral Vascular Diseases / Q000503:physiopathology / Q000534:rehabilitation*; D011788:Quality of Life; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D013995:Time; D016896:Treatment Outcome