title: Irritant hand dermatitis: severity of disease, occupational exposure to skin irritants and preventive measures 5 years after initial diagnosis.
abstract: Irritant contact dermatitis (ICD) is often chronic; its aetiology frequently being related to occupational exposure. Management of ICD involves persistent reduction in exposure to skin irritants such as water, detergents and prolonged occlusion by gloves. The aim of this study was to determine the severity of hand dermatitis 5 years after initial diagnosis and to find out what factors were related to this outcome. A questionnaire survey was carried out on severity of hand dermatitis, exposure to skin irritants and preventive measures, 5 years after initial ICD diagnosis. Of a cohort of 201 patients with ICD, 172 received the questionnaire and 124 (72%) responded. 5 years after initial diagnosis, 50% still had medium and 32% severe hand dermatitis. Patients with severe ICD and high exposure showed low levels of prevention and difficulty in changing their occupational exposure. Use of emollients was predominantly therapeutic rather than preventive. Occupation was changed in 57% of cases, of which 46% was permanent. In this population, ICD is a chronic disease; implementation of secondary preventive measures appears to fail. In occupations with high exposure to skin irritants, implementation of permanent exposure reduction is more difficult, compared to occupations with a medium level of exposure. High exposures might have led to change of occupation; medium exposures could have been reduced to low levels. In occupations with high exposure, women were overrepresented.
authors.affiliation: Department of Dermatology, Groningen University Hospital, PO Box 30.001. 9700 RB Groningen, The Netherlands. f.h.w.jungbauer@derm.azg.nl
authors.forename: F H W
authors.initials: FH
authors.lastname: Jungbauer
authors.forename: P
authors.initials: P
authors.lastname: van der Vleuten
authors.forename: J W
authors.initials: JW
authors.lastname: Groothoff
authors.forename: P J
authors.initials: PJ
authors.lastname: Coenraads
mesh_terms: D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000473:pathology / Q000517:prevention & control*; D009783:Dermatitis, Occupational / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000473:pathology / Q000517:prevention & control*; D005260:Female; D006229:Hand Dermatoses / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000473:pathology / Q000517:prevention & control*; D006801:Humans; D007509:Irritants / Q000009:adverse effects*; D008297:Male; D009426:Netherlands / Q000453:epidemiology; D016273:Occupational Exposure / Q000009:adverse effects; D010353:Patient Education as Topic; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires
chemical_list: D007509:Irritants