Sperm tail agenesis in a case of consanguinity.
OBJECTIVE
To report a case of 100% teratozoospermia in a patient whose family history presented a high degree of consanguinity.


METHODS
Case report.


METHODS
University-based andrology clinic.


METHODS
A 27-year-old man undergoing infertility evaluation.


METHODS
None.


METHODS
Serum hormone analysis, standard (World Health Organization) semen quality evaluation, sperm ultrastructure, lymphocytic karyotype, and polymerase chain reaction screening for Y chromosome microdeletions in peripheral blood.


RESULTS
One hundred percent teratozoospermia characterized by shape alterations of the heads and tail agenesis on standard morphology evaluation, which was confirmed using electron microscopy.


CONCLUSIONS
A case of familial infertility in a consanguineous patient characterized by morphological abnormalities of spermatozoa such as tail agenesis, chromatin subcondensation, and residual cytoplasmic droplets.
Latini
Maurizio
M
Department of Medical Pysiopathology, University of Rome "La Sapienza.",Rome, Italy. maurizio.latini@uniroma1.it
Gandini
Loredana
L
Lenzi
Andrea
A
Romanelli
Francesco
F
D000328:Adult; D003241:Consanguinity; D006801:Humans; D007248:Infertility, Male / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008854:Microscopy, Electron; D013076:Sperm Count; D013081:Sperm Motility; D013082:Sperm Tail / Q000648:ultrastructure*; D013094:Spermatozoa / Q000002:abnormalities*