Familial hypercholesterolemia in South Africa.
South Africa, especially the Caucasian part of the population, has one of the highest incidences of familial hypercholesterolemia in the world. The founder effect in this region has led to this high incidence and to a limited number of mutations in the low-density lipoprotein-receptor gene. This chapter describes current situation concerning the management of familial hypercholesterolemia in South Africa.
Marais
Adrian David
AD
Lipidology Division of Internal Medicine and MRC Cape Heart Group, University of Cape Town Health Science Faculty, Observatory, South Africa. dmarais@capeheart.uct.ac.za
Firth
Jean Catherine
JC
Blom
Dirk Jacobus
DJ
D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000453:epidemiology*; D015994:Incidence; D013019:South Africa / Q000453:epidemiology