A2E, a fluorophore of RPE lipofuscin: can it cause RPE degeneration?
Sparrow
Janet R
JR
Department of Ophthalmology and Chemistry, Columbia University, New York, NY 10032, USA. jrs88@columbia.edu
Cai
Bolin
B
Fishkin
Nate
N
Jang
Young Pyo
YP
Krane
Sonja
S
Vollmer
Heidi R
HR
Zhou
Jilin
J
Nakanishi
Koji
K
D000818:Animals; D006801:Humans; D008027:Light; D010857:Pigment Epithelium of Eye / Q000378:metabolism*; D011832:Radiation Injuries / Q000150:complications; D012160:Retina / Q000378:metabolism / Q000528:radiation effects; D012162:Retinal Degeneration / Q000209:etiology*; D012168:Retinal Pigments / Q000378:metabolism*; D012172:Retinaldehyde / Q000737:chemistry / Q000378:metabolism; D012176:Retinoids / Q000378:metabolism*; D013237:Stereoisomerism
C112040:A2-E (N-retinylidene-N-retinylethanolamine); D012168:Retinal Pigments; D012176:Retinoids; D012172:Retinaldehyde