title: Carcinoma of sigmoid colon following urinary diversion: a case report and review of literature.
abstract: BACKGROUND
  The association of ureterosigmoidostomy with colonic cancer is well established. A 100-fold increased risk of malignancy has been proposed in association with ureterosigmoidostomy. Characteristically there is a latent period of around 20-30 years before the occurrence of cancer.
  
  
  METHODS
  An unusual case of adenocarcinoma of the colon in a 36-year-old patient is presented. The patient underwent three operations in his infancy for exstrophy but after failure to close bladder, ureterosigmoidostomy was attempted at the age of 5 years and was converted to an ileal conduit after 8 months. At the age of 36 years, 30 years following ileal conduit urinary diversion for exstrophy, he presented in emergency with large bowel obstruction due to adenocarcinoma of the sigmoid colon.
  
  
  CONCLUSIONS
  Patients who undergo urinary diversion for exstrophy may be kept on a regular follow-up surveillance colonoscopy as most of these young adults may later present with vague abdominal symptoms which may not be taken seriously until they increase to an extent as to present with intestinal obstruction as in the present case.
authors.affiliation: General Surgery, L & D Hospital, Lewsey Road, Luton, UK. MKHAN702@AOL.COM
authors.forename: Muhammad N
authors.initials: MN
authors.lastname: Khan
authors.forename: Abul H
authors.initials: AH
authors.lastname: Naqvi
authors.forename: Richard E
authors.initials: RE
authors.lastname: Lee