[Concepts and therapeutic perspectives of proteomics].
The present paper aims at clarifying some important aspects of proteomics, i.e. the large scale analysis of proteins. To this purpose, the main types of proteomic analyses are presented, i.e. those aiming at determining expression levels and those aiming at unravelling protein-protein interactions networks. Their performances and limitations are outlined, as well as their potential applications in biomedicine, to give an reasoned view of the current state of the art.
Lescuyer
Pierre
P
Laboratoire de bioénergétique cellulaire et pathologique, DRDC/BECP, CEA-Grenoble, 17, rue des Martyrs, 38054 Grenoble 9, France.
Chevallet
Mireille
M
Rabilloud
Thierry
T
D000818:Animals; D030342:Genetic Diseases, Inborn / Q000235:genetics; D006801:Humans; D020543:Proteome; D040901:Proteomics / Q000379:methods*
D020543:Proteome