Nomenclature of the finer branches of the biliary tree: canals, ductules, and ductular reactions in human livers.
The work of liver stem cell biologists, largely carried out in rodent models, has now started to manifest in human investigations and applications. We can now recognize complex regenerative processes in tissue specimens that had only been suspected for decades, but we also struggle to describe what we see in human tissues in a way that takes into account the findings from the animal investigations, using a language derived from species not, in fact, so much like our own. This international group of liver pathologists and hepatologists, most of whom are actively engaged in both clinical work and scientific research, seeks to arrive at a consensus on nomenclature for normal human livers and human reactive lesions that can facilitate more rapid advancement of our field.
Roskams
Tania A
TA
Department of Pathology, University Hospitals, University of Leuven, Leuven, Belgium.
Theise
Neil D
ND
Balabaud
Charles
C
Bhagat
Govind
G
Bhathal
Prithi S
PS
Bioulac-Sage
Paulette
P
Brunt
Elizabeth M
EM
Crawford
James M
JM
Crosby
Heather A
HA
Desmet
Valeer
V
Finegold
Milton J
MJ
Geller
Stephen A
SA
Gouw
Annette S H
AS
Hytiroglou
Prodromos
P
Knisely
A S
AS
Kojiro
Masamichi
M
Lefkowitch
Jay H
JH
Nakanuma
Yasuni
Y
Olynyk
John K
JK
Park
Young Nyun
YN
Portmann
Bernard
B
Saxena
Romil
R
Scheuer
Peter J
PJ
Strain
Alastair J
AJ
Thung
Swan N
SN
Wanless
Ian R
IR
West
A Brian
AB
D001659:Biliary Tract / Q000033:anatomy & histology*; D006801:Humans; D008099:Liver / Q000473:pathology; D009626:Terminology as Topic