Sequential enolboration/hydroformylation/aldol addition: a new one-pot cascade reaction for the regio- and diastereoselective formation of carbocyclic quaternary centres from acyclic olefins.
Starting from unsaturated carbonyl compounds a mild new cascade reaction involving enolboration, rhodium-catalysed hydroformylation and intramolecular aldol addition in a regio- and diastereoselective fashion leads to cyclic compounds containing highly-functionalised quaternary carbon centres.
Keränen
Mark D
MD
Fachbereich Chemie, Organische Chemie I, Universität Dortmund, Otto-Hahn-Str. 6, D-44227 Dortmund, Germany.
Eilbracht
Peter
P