title: Early graft failure due to a veno-occlusive disease after a pediatric living donor liver transplantation.
abstract: A 10-month-old boy with biliary atresia after Kasai procedure underwent a living donor liver transplantation (LDLT). Five days after the LDLT, high fever and increased ascites followed by poor bile drainage was accompanied by elevation of serum liver enzymes. Liver biopsy showed occlusion of the central veins by fibro-edematous endothelium and submassive necrosis of the parenchyma. Veno-occlusive disease (VOD) was suspected, and re-LDLT was urgently performed because of deterioration of hepatic failure. There are few cases of VOD after liver transplantation and this is the first one in an infant after LDLT.
authors.affiliation: Department of Pediatric Surgery, Kumamoto University Hospital, Kumamoto, Japan.
authors.forename: Toshiya
authors.initials: T
authors.lastname: Izaki
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Inomata
authors.forename: Katsuhiro
authors.initials: K
authors.lastname: Asonuma
authors.forename: Hideaki
authors.initials: H
authors.lastname: Okajima
authors.forename: Hajime
authors.initials: H
authors.lastname: Ohshiro
authors.forename: Mikako
authors.initials: M
authors.lastname: Ueno
authors.forename: Rieko
authors.initials: R
authors.lastname: Hamamoto
authors.forename: Ken-Ichi
authors.initials: K
authors.lastname: Iyama
authors.forename: Koichi
authors.initials: K
authors.lastname: Tanaka
mesh_terms: D006083:Graft Occlusion, Vascular / Q000473:pathology*; D006504:Hepatic Veno-Occlusive Disease / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007223:Infant; D008099:Liver / Q000473:pathology; D016031:Liver Transplantation / Q000009:adverse effects*; D019520:Living Donors; D008297:Male