Antioxidant and free radical scavenging activities of 5,7,3'-trihydroxy-3,6,4'-trimethoxyflavone from Brickellia veronicaefolia.
The antioxidant and antiradical activities of 5,7,3'-trihydroxy-3,6,4'-trimethoxyflavone or centaureidin isolated and characterized from Brickellia veronicaefolia were elucidated by heat-induced oxidation in a beta-carotene and linoleic acid system and by the 1,1-diphenyl-2-picrylhydrazyl decoloration test. The centaureidin (32.1%) exhibited antioxidative activity less than that of BHT (95.5%) and alpha-tocopherol (95.9%) on oxidation in a beta-carotene and linoleic acid system. A moderate antiradical effect (47.6%) compared with BHT (96.7%) and alpha-tocopherol (94.6%) in DPPH decoloration test was found.
Pérez G
R M
RM
Laboratorio de Investigacion de Productos Naturales, Escuela Superior de Ingeniería Química e Industias extractivas IPN, Punto fi jo 16, col. Torres Lindavista cp 07708, México D.F. México. rmpg@prodigy.net.mx
Vargas S
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Martinez M
F J
FJ
Cordova R
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D000975:Antioxidants / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D019659:Asteraceae; D001713:Biphenyl Compounds; D005419:Flavonoids / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D016166:Free Radical Scavengers / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D019787:Linoleic Acid / Q000737:chemistry; D008517:Phytotherapy; D010851:Picrates; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D018515:Plant Leaves; D019207:beta Carotene / Q000737:chemistry
D000975:Antioxidants; D001713:Biphenyl Compounds; D005419:Flavonoids; D016166:Free Radical Scavengers; D010851:Picrates; D010936:Plant Extracts; D019207:beta Carotene; C083161:centaureidin; D019787:Linoleic Acid; C004931:1,1-diphenyl-2-picrylhydrazyl