A high-throughput NMR-based ee-assay using chemical shift imaging.
The throughput of a previously described NMR-based -assay has been increased by a factor of at least 4 as a consequence of adapting the system to chemical shift imaging; by using a 19-capillary system the enantiomeric purity of 5600 samples can be measured per day.
Reetz
Manfred T
MT
Max-Planck-Institut fur Kohlenforschung, D-45470 Mulheim/Ruhr, Germany. reetz@mpi-muelheim.mpg.de
Tielmann
Patrick
P
Eipper
Andreas
A
Ross
Alfred
A
Schlotterbeck
Gotz
G