Interferon induced glomerular disease in a patient with chronic hepatitis C.
Chronic hepatitis C manifests with many extrahepatic features including renal involvement. However, less commonly, interferon therapy for chronic hepatitis C can also result in renal involvement and we describe a case when interferon therapy resulted in minimal change glomerulopathy, a form of involvement which, carries a good prognosis. Our patient developed nephrotic syndrome while on interferon therapy and HCV RNA levels were undetectable at that time. The disease showed excellent response to steroid therapy.
Suresh
R L
RL
Department of Medicine, Hospital Selayang, Lebuhraya Kepong-Selayang, Batu Caves, 68100 Selangor.
Suryati
Y
Y
Merican
I
I
D000328:Adult; D000998:Antiviral Agents / Q000009:adverse effects*; D004359:Drug Therapy, Combination; D019698:Hepatitis C, Chronic / Q000188:drug therapy*; D006801:Humans; D007372:Interferons / Q000009:adverse effects*; D008111:Liver Function Tests; D008297:Male; D009404:Nephrotic Syndrome / Q000139:chemically induced*; D012254:Ribavirin / Q000008:administration & dosage
D000998:Antiviral Agents; D012254:Ribavirin; D007372:Interferons