title: Extraosseous accumulation of 99mTc-MDP in lymph node metastases of small cell carcinoma of the esophagus.
abstract: We report a case of esophageal carcinoma that showed extraosseous accumulation of 99mTc-MDP in lymph node metastases to the cervical and paracardial lymph nodes. There are few cases showing abnormal extraosseous accumulation of 99mTc-MDP in esophageal cancer lesion. The patient was a 53-year-old man with advanced esophageal cancer. Bone scintigraphy demonstrated extraosseous accumulations in left supraclavicular and paracardial lymph node metastases. The histopathological diagnosis was small cell carcinoma of the esophagus, which is a rare disease with aggressive behavior and poor prognosis. Our patient underwent 2 courses of systemic chemotherapy (CDDP + VP16), but died of rapidly growing systemic metastases 5 months after the initial treatment.
authors.affiliation: Department of Radiology, Saitama Medical Center, Saitama Medical School, Kawagoe, Japan. taketaka@saitama-med.ac.jp
authors.forename: Takeo
authors.initials: T
authors.lastname: Takahashi
authors.forename: Kikuo
authors.initials: K
authors.lastname: Machida
authors.forename: Norinari
authors.initials: N
authors.lastname: Honda
authors.forename: Makoto
authors.initials: M
authors.lastname: Hosono
authors.forename: Shinya
authors.initials: S
authors.lastname: Oku
authors.forename: Hisato
authors.initials: H
authors.lastname: Osada
authors.forename: Osamu
authors.initials: O
authors.lastname: Murata
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Nishimura
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Ohno
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000378:metabolism; D018288:Carcinoma, Small Cell / Q000000981:diagnostic imaging* / Q000378:metabolism* / Q000556:secondary; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism*; D006801:Humans; D033162:Incidental Findings; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000378:metabolism; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D013669:Technetium Tc 99m Medronate / Q000493:pharmacokinetics*
chemical_list: D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate