Elastophagocytosis: a feature of resolving Sweet's syndrome.
We report the case of a patient with atypical Sweet's syndrome characterized by an annular erythema that showed consumption of elastic fibres by giant cells and histiocytes. Although the lesions were found on sun-exposed sites and the first biopsy demonstrated extensive elastophagocytosis, our patient did not have photodamaged skin clinically. A repeat biopsy 5 weeks later demonstrated an abundant collection of neutrophils supporting the diagnosis of Sweet's syndrome. To our knowledge, an elastolytic granulomatous reaction pattern has not been previously reported in Sweet's syndrome.
Loo
W J
WJ
Department of Dermatology, Addenbrookes' NHS Trust, Cambridge, UK. wjloo@hotmail.com
Rytina
E
E
Banfield
C
C
D000328:Adult; D020405:Dermis / Q000473:pathology*; D004547:Elastic Tissue / Q000473:pathology*; D005260:Female; D006801:Humans; D009504:Neutrophils / Q000473:pathology; D010587:Phagocytosis; D016463:Sweet Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*