Combinatorial chemistry and high-throughput screening for the discovery of organocatalysts.
In recent years, interest in organocatalysis, the catalysis with small organic molecules, has been revitalized. Independently, high-throughput-screening and combinatorial chemistry became practical methodologies in the discovery of novel catalytic entities. The logical extension of these methodologies to organocatalysis has led to several interesting results, which are highlighted in this review.
Fonseca
María Hechavarría
MH
Max Planck Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, D-45470 Muelheim an der Ruhr, Germany.
List
Benjamin
B
D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods; D020650:Combinatorial Chemistry Techniques / Q000379:methods* / Q000639:trends; D015195:Drug Design; D006838:Hydrocarbons; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism; D008956:Models, Chemical; D009942:Organometallic Compounds / Q000737:chemistry* / Q000378:metabolism
D006838:Hydrocarbons; D009942:Organometallic Compounds; C030011:carbene; D008697:Methane