Restless legs syndrome due to interferon-alpha.
A patient developed restless legs symptoms paralleling the course of interferon-alpha (IFN alpha) therapy for chronic hepatitis C. Symptoms began during a course of IFN alpha, resolved with its suspension, and recurred on rechallenge. Restless legs syndrome may thus be an adverse effect of IFN alpha treatment.
LaRochelle
Jeffrey S
JS
Wilford Hall Medical Center, Lackland AFB, San Antonio, Texas, USA.
Karp
Barbara I
BI
D000998:Antiviral Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001706:Biopsy; D019698:Hepatitis C, Chronic / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects* / Q000627:therapeutic use; D008099:Liver / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012148:Restless Legs Syndrome / Q000139:chemically induced* / Q000175:diagnosis; D012720:Severity of Illness Index
D000998:Antiviral Agents; D016898:Interferon-alpha