title: The longest use of liposomal amphotericin B and 5-fluorocytosine in neonatal renal candidiasis.
abstract: Bilateral fungal obstruction of the renal collecting system is rare in infancy. Treatment options include medical or surgical procedures. Reports of successful medical treatment with liposomal amphotericin B have been published but the duration of treatment is controversial. We report a 3-week-old preterm baby with myelomeningocele who had experienced acute renal failure related to bilateral renal fungus balls, which improved with percutaneous nephrostomy and 12 weeks of liposomal amphotericin B intravenously combined with 5-fluorocytosine orally for 9 weeks.
authors.affiliation: Department of Pediatric Nephrology, Marmara University School of Medicine, Tophanelioglu cd, no 13-15, 81190 Altunizade, Istanbul, Turkey. nesebiyikli@superonline.com
authors.forename: Nese Karaaslan
authors.initials: NK
authors.lastname: Biyikli
authors.forename: Halil
authors.initials: H
authors.lastname: Tugtepe
authors.forename: Ihsan
authors.initials: I
authors.lastname: Akpinar
authors.forename: Harika
authors.initials: H
authors.lastname: Alpay
authors.forename: Eren
authors.initials: E
authors.lastname: Ozek
mesh_terms: D058186:Acute Kidney Injury / Q000188:drug therapy* / Q000382:microbiology*; D000666:Amphotericin B / Q000008:administration & dosage*; D000935:Antifungal Agents / Q000008:administration & dosage*; D002177:Candidiasis / Q000188:drug therapy*; D005260:Female; D005437:Flucytosine / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D007674:Kidney Diseases / Q000188:drug therapy* / Q000382:microbiology*; D008081:Liposomes; D013997:Time Factors
chemical_list: D000935:Antifungal Agents; D008081:Liposomes; D000666:Amphotericin B; D005437:Flucytosine