Synthesis of a hexasaccharide fragment of group E streptococci polysaccharide and the tetrasaccharide repeating unit of E. coli O7:K98:H6.
Syntheses of a hexasaccharide, the dimer of the repeating unit of the group E streptococci polysaccharide, and a tetrasaccharide, the repeating unit of the E. coli O7:K98:H6, were achieved by constructing alternate alpha-L-(1-->2)- and alpha-L-(1-->3)-linked L-rhamnopyranose backbones and substituting with beta-linked D-glucopyranose side chains for the former, and a D-glucopyranosyluronate branch for the latter, respectively, at O-2 of the L-rhamnose ring.
Zeng
Youlin
Y
Research Center for Eco-Environmental Sciences, Academia Sinica, PO Box 2871, Beijing 100085, PR China.
Kong
Fanzuo
F
D002240:Carbohydrate Sequence; D004926:Escherichia coli / Q000737:chemistry*; D005936:Glucans / Q000737:chemistry; D005965:Glucuronates / Q000737:chemistry; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D012210:Rhamnose / Q000737:chemistry; D013291:Streptococcus / Q000737:chemistry* / Q000145:classification*
D005936:Glucans; D005965:Glucuronates; D009844:Oligosaccharides; C008763:panose; D012210:Rhamnose