Receptor clustering: nothing succeeds like success.
By experimentally limiting the amount of receptor molecules available in a postsynaptic neuron in Drosophila, it has been shown that receptors can preferentially cluster opposite active zones with a high release probability. This asymmetry in receptor distribution can alter the apparent probability and calcium-dependence of neurotransmitter release.
Griffith
Leslie C
LC
Department of Biology and Volen Center for Complex Systems, MS008, Brandeis University, 415 South St., Waltham, Massachusetts 02454-9110, USA.griffith@brandeis.edu
D000818:Animals; D004330:Drosophila; D029721:Drosophila Proteins / Q000235:genetics; D009154:Mutation / Q000235:genetics; D009469:Neuromuscular Junction / Q000502:physiology; D009473:Neuronal Plasticity / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000378:metabolism*; D017729:Presynaptic Terminals / Q000378:metabolism*; D017470:Receptors, Glutamate / Q000235:genetics / Q000378:metabolism*; D013569:Synapses / Q000378:metabolism / Q000502:physiology*
D029721:Drosophila Proteins; D018377:Neurotransmitter Agents; D017470:Receptors, Glutamate; C483908:glutamate receptor III, Drosophila