title: Use of assisted reproductive technologies and anesthesia in a patient with primary pulmonary hypertension.
abstract: OBJECTIVE
  To report the use of assisted reproductive technologies (ART) in a patient with primary pulmonary hypertension.
  
  
  METHODS
  Case report.
  
  
  METHODS
  University medical center.
  
  
  METHODS
  A 28-year-old nulliparous woman with primary pulmonary hypertension (PPH) treated with continuous intravenous epoprostenol.
  
  
  METHODS
  Ovarian stimulation, egg retrieval, general anesthesia, and pregnancy by surrogate carrier.
  
  
  METHODS
  Successful ART cycle(s) in patient with PPH and successful gestational carrier pregnancy.
  
  
  RESULTS
  Successful pregnancy by surrogate gestational carrier.
  
  
  CONCLUSIONS
  Assisted reproductive technologies and a surrogate gestational carrier were a successful reproductive option for a patient with primary pulmonary hypertension. Ovarian stimulation, oocyte retrieval, and general anesthesia are not without risk but were well tolerated in this case. Multidisciplinary involvement in the planning and administration of such procedures is necessary for optimal outcomes in these patients.
authors.affiliation: Department of Anesthesiology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
authors.forename: Elise
authors.initials: E
authors.lastname: Metzler
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Ginsburg
authors.forename: Lawrence C
authors.initials: LC
authors.lastname: Tsen
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D000959:Antihypertensive Agents / Q000008:administration & dosage; D011464:Epoprostenol / Q000008:administration & dosage; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy; D007260:Infusion Pumps; D009865:Oocytes; D011247:Pregnancy; D013533:Gestational Carriers; D020858:Tissue and Organ Harvesting; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents; D011464:Epoprostenol