Macular burn after transpupillary thermotherapy for occult choroidal neovascularization.
OBJECTIVE
To report a case of severe macular burn as a complication of transpupillary thermotherapy treatment for occult choroidal neovascularization.


METHODS
Interventional case report.


METHODS
A 65-year-old man developed a severe macular burn following transpupillary thermotherapy treatment.


RESULTS
Before treatment, fluorescein angiography and indocyanine green angiography showed a progressive, ill-defined leakage corresponding to the presence of occult choroidal neovascularization. One month after treatment, fundus examination disclosed macular atrophy. The early phases of fluorescein angiography and indocyanine green angiography showed that the macular choroidal filling time had worsened dramatically. At the late phase of indocyanine green angiography, the initial hyperfluorescence of choroidal neovascularization was replaced by a persistent, markedly hypofluorescent area.


CONCLUSIONS
Prolonged choroidal filling may be a risk factor for macular burn and choroidal occlusion after transpupillary thermotherapy. In such cases, we suggest that transpupillary thermotherapy should be considered with caution and, when applied, that its intensity should be reduced.
Benhamou
Nathanael
N
Department of Ophthalmology, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France. nathanael_benhamou@yahoo.fr
Cohen
Salomon Y
SY
Erginay
Ali
A
Uzzan
Joel
J
Brasseur
Gerard
G
Avni
Isaac
I
Gaudric
Alain
A
D000368:Aged; D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000628:therapy*; D005126:Eye Burns / Q000175:diagnosis / Q000209:etiology*; D005451:Fluorescein Angiography; D006801:Humans; D006979:Hyperthermia, Induced / Q000009:adverse effects*; D007208:Indocyanine Green; D008266:Macula Lutea / Q000293:injuries* / Q000473:pathology; D008297:Male; D011680:Pupil
D007208:Indocyanine Green