[Disseminated peritoneal leiomyomatosis--case report and literature review].
Leiomyomatosis peritonealis disseminata(LPD) is a rare smooth muscle pathology, characterized by the presence of multiple tumors in peritoneal cavity mimicking a malignant process with metastases. The diagnosis may be difficult in some cases as the results of ultrasonography and CT imaging may suggest malignancy. The final diagnosis was made on biopsy and pathologic examination performed during surgery. Exposure to estrogens probably plays the main etiologic role. In this report we describe the diagnostic difficulties and the clinical course of LPD in 45 year old women. The surgical treatment consisted on hysterectomy and removal of multiple nodules located in intestinal serosa. The additional hormonal treatment with GnRh agonist was applied. This report documents the possibility of effective surgical and hormonal treatment.
Sobiczewski
Piotr
P
Klinika Nowotworów Narzadów Płciowych Kobiecych Centrum Onkologii w Warszawie.
Bidziński
Mariusz
M
Radziszewski
Jakub
J
Panek
Grzegorz
G
Olszewski
Wojciech
W
Tacikowska
Małgorzata
M
D003937:Diagnosis, Differential; D004967:Estrogens / Q000009:adverse effects; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000037:antagonists & inhibitors; D006801:Humans; D018231:Leiomyomatosis / Q000473:pathology* / Q000601:surgery*; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000473:pathology* / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome
D004967:Estrogens; D007987:Gonadotropin-Releasing Hormone