title: Fertility preserving radical cystectomy in a young female with malignant mesenchymal tumour of urinary bladder.
abstract: Fertility preserving radical cystectomy has been reported in young males with leiomyosarcoma and transitional cell carcinoma but not in females. We present a case of 19-year-old lady with mesenchymal tumour of urinary bladder with myogenic differentiation who was managed with fertility preserving radical cystectomy. As the patient was just 19-year-old a consensus was made to preserve the internal genitalia (both the ovaries and uterus) in order to restore the fertility. Immunohistochemistry was compatible with mesenchymal tumour with myogenic differentiation. Adjuvant chemotherapy (Ifosfamide, CDDP and Etocid) was given. Patient is doing well at a follow-up of 6 months.
authors.affiliation: Department of Urology, All India Institute of Medical Sciences, New Delhi, 110029, India. narmadagupta@hotmail.com
authors.forename: N P
authors.initials: NP
authors.lastname: Gupta
authors.forename: M S
authors.initials: MS
authors.lastname: Ansari
authors.forename: Anurag
authors.initials: A
authors.lastname: Khaitan
authors.forename: R
authors.initials: R
authors.lastname: Dawar
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant / Q000379:methods; D015653:Cystectomy / Q000379:methods*; D005260:Female; D005298:Fertility; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000473:pathology; D012509:Sarcoma / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000601:surgery*; D014547:Urinary Diversion; D013520:Urologic Surgical Procedures / Q000379:methods
chemical_list: D000970:Antineoplastic Agents