Widespread capillary malformation associated with global developmental delay and megalencephaly.
Although port wine stains are seen in 0.3% births, widespread cutaneous capillary malformations are unusual and an association with static gliosis has not been previously reported. This is a report of a 3-year-old boy with a fixed widespread capillary naevus (port wine stain), megalencephaly and global developmental, and features of gliosis on brain magnetic resonance imaging (MRI).
Leech
Suzanne N
SN
Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK Department of Paediatric Neurology, Newcastle General Hospital, Newcastle upon Tyne, UK Department of Radiology, Newcastle General Hospital, Newcastle upon Tyne, UK Department of Clinical Genetics, Centre for Life, Newcastle upon Tyne, UK.
Taylor
Aileen E M
AEM
Ramesh
Venkat
V
Birchall
Daniel
D
Ann Lynch
Sally
S
D000015:Abnormalities, Multiple / Q000175:diagnosis; D001921:Brain / Q000002:abnormalities* / Q000473:pathology; D002196:Capillaries / Q000002:abnormalities*; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000150:complications / Q000175:diagnosis*; D019066:Facies; D005911:Gliosis / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D019339:Port-Wine Stain / Q000150:complications / Q000175:diagnosis*