Assisted hatching is associated with a higher ectopic pregnancy rate.
In a retrospective analysis of 623 clinical pregnancies conceived after IVF, a 5.4% ectopic pregnancy rate (14/258 clinical pregnancies) was found in cases where assisted hatching (AH) was performed compared to 2.2% (8/365) in the group without assisted hatching. In view of the widespread use of AH, it may be relevant to assess the effect of AH on the incidence of ectopic pregnancy in a large multicenter effort.
Jun
Sunny H
SH
Milki
Amin A
AA
D005260:Female; D006801:Humans; D015994:Incidence; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000453:epidemiology / Q000209:etiology*; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects*; D015044:Zona Pellucida / Q000502:physiology*