Does a family history of coronary heart disease modify the relationship between physical activity and blood pressure in young adults?
BACKGROUND
The purpose of this study was to examine the relationships between physical activity, a family history (FH) of coronary heart disease (CHD), and blood pressure (BP) in young adults. We were specifically interested in determining whether the relationship between moderate-to-vigorous physical activity and BP was modified by a FH of CHD.


METHODS
Subjects were 230 (103 males, 127 females) university students. Family history was self-reported and habitual physical activity was assessed with a 3-day activity diary. Indicators of habitual physical activity included estimated daily energy expenditure (EE) and EE in moderate-to-vigorous physical activity (MVPA) [median metabolic equivalent (MET) > or =4.8] and inactivity (IA) (MET<2.8). Blood pressure was measured by an automated device according to standard procedures.


RESULTS
A large proportion of the sample (63% of males and 68% of females) reported a FH of CHD. In general, correlations between physical activity and BP were low (r<0.30), but in the expected direction (i.e., positive for IA and negative for MVPA and EE). In males IA was significantly related to BP (r =0.25-0.29), but MVPA was not significantly related to BP (r= -0.01 to -0.16). In females diastolic BP was significantly related to IA (r= -0.21) and total EE (r= -0.18). Total EE was significantly correlated to DBP (r= -0.22) in males and to mean arterial pressure (r= -0.18) in females. No significant differences in BP were found between subjects with or without a FH of CHD. Slightly stronger correlations emerged between MVPA and BP for subjects with a negative FH of CHD compared to those with a positive FH of CHD.


CONCLUSIONS
These data show a significant association between sedentary behavior and blood pressure in young adults. It is suggestive that the magnitude of the relationship between MVPA and BP may be modified by a FH of CHD. Thus, individuals with a FH of CHD may not be as responsive to increased levels of MVPA compared to those without a FH of CHD.
Garcia
Kristen
K
University of Wyoming, Wyoming, USA.
Eisenmann
Joey C
JC
Bartee
R Todd
RT
D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D003327:Coronary Disease / Q000235:genetics* / Q000503:physiopathology*; D004734:Energy Metabolism / Q000502:physiology; D005260:Female; D020022:Genetic Predisposition to Disease; D015438:Health Behavior; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D012737:Sex Factors