First total synthesis of cucurbitaxanthin A applying regioselective ring opening of tetrasubstituted epoxides.
The synthesis of cucurbitaxanthin A 1 was accomplished via the C(15)-3,6-epoxides 7e and 7f prepared by regioselective ring opening of the 3-hydroxy-5,6-epoxides 6e and 6f.
Yamano
Yumiko
Y
Kobe Pharmaceutical University, Motoyamakita-machi, Higashi-nada-ku, Kobe 658-8558, Japan.
Ito
Masayoshi
M
D002338:Carotenoids / Q000138:chemical synthesis*; D004852:Epoxy Compounds / Q000138:chemical synthesis*
D004852:Epoxy Compounds; D002338:Carotenoids