title: Catalytic beacons for the detection of DNA and telomerase activity.
abstract: DNA and telomerase activity are detected by a DNAzyme generated upon hybridization and opening of a functional catalytic beacon.
authors.affiliation: The Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
authors.forename: Yi
authors.initials: Y
authors.lastname: Xiao
authors.forename: Valeri
authors.initials: V
authors.lastname: Pavlov
authors.forename: Tamara
authors.initials: T
authors.lastname: Niazov
authors.forename: Arnon
authors.initials: A
authors.lastname: Dishon
authors.forename: Moshe
authors.initials: M
authors.lastname: Kotler
authors.forename: Itamar
authors.initials: I
authors.lastname: Willner
mesh_terms: D002384:Catalysis; D002452:Cell Count; D004247:DNA / Q000032:analysis* / Q000378:metabolism; D021881:DNA, Catalytic / Q000737:chemistry / Q000378:metabolism; D004789:Enzyme Activation; D006367:HeLa Cells; D006801:Humans; D015336:Molecular Probe Techniques; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization; D009696:Nucleic Acids / Q000737:chemistry*; D010777:Photochemistry; D012680:Sensitivity and Specificity; D019098:Telomerase / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism*; D013997:Time Factors
chemical_list: D021881:DNA, Catalytic; D009696:Nucleic Acids; D004247:DNA; D019098:Telomerase