title: Diastereoselective zinc-catalyzed conjugate addition of alkynes.
abstract: [reaction: see text] The conjugate addition of in situ generated zinc alkynylides is reported. The use of chiral, ephedrine derived acceptors provides access to enantiomerically enriched beta-alkynyl acids in good yields.
authors.affiliation: Laboratorium für Organische Chemie, ETH-Hönggerberg, CH-8093 Zurich, Switzerland.
authors.forename: Thomas F
authors.initials: TF
authors.lastname: Knöpfel
authors.forename: Dean
authors.initials: D
authors.lastname: Boyall
authors.forename: Erick M
authors.initials: EM
authors.lastname: Carreira