New rapamycin derivatives by precursor-directed biosynthesis.
Lowden
Philip A S
PA
School of Chemistry, University of Exeter, Stocker Road, Exeter, EX4 4QD, UK. P.Lowden@bbk.ac.uk
Böhm
Günter A
GA
Metcalfe
Su
S
Staunton
James
J
Leadlay
Peter F
PF
D002264:Carboxylic Acids / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D007536:Isomerism; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009097:Multienzyme Complexes / Q000235:genetics / Q000378:metabolism; D011355:Prodrugs; D020123:Sirolimus / Q000737:chemistry* / Q000378:metabolism*; D012997:Solvents / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D013302:Streptomyces
D002264:Carboxylic Acids; D009097:Multienzyme Complexes; D011355:Prodrugs; D012997:Solvents; D020123:Sirolimus