Tuberculosis in renal transplants in Rio de Janeiro.
Retrospective analysis of 982 renal transplants over 21 years (1981 to 2002) sought to evaluate the prevalence of tuberculosis (TB). This analysis included 74 patients: 30 with a past TB history, who had INH prophylaxis since the beginning of immunosuppression, and 44 who only became TB infected after receiving transplants. The diagnosis of TB was made by a compatible medical situation with bacteriological/histological confirmation, which when not possible, underwent a therapeutic test occur. The average time for the illness to surge was 3 years. The mortality rate was 34.9% (15/44). Patients with hepatitis C were more affected. Among those who used INH prophylaxis only one contracted TB, showing that the drug displayed a protection rate of 96.6% (29/30).
Matuck
T Azevedo
TA
Renal Transplant Unit, Hospital Geral de Bonsucesso/Ministério da Saúde, Rio de Janeiro, RJ, Brazil.
Brasil
P
P
Alvarenga
M de Fátima Arruda Correa
Mde F
Morgado
L
L
Rels
M Drumond
MD
da Costa
A C Pires
AC
Araújo
M
M
Rodrigues
M E
ME
de Carvalho
D de Boni Monteiro
Dde B
D000995:Antitubercular Agents / Q000627:therapeutic use; D001938:Brazil / Q000453:epidemiology; D005500:Follow-Up Studies; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D012189:Retrospective Studies; D013997:Time Factors; D014376:Tuberculosis / Q000188:drug therapy / Q000453:epidemiology*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000453:epidemiology
D000995:Antitubercular Agents