Early graft failure due to a veno-occlusive disease after a pediatric living donor liver transplantation.
A 10-month-old boy with biliary atresia after Kasai procedure underwent a living donor liver transplantation (LDLT). Five days after the LDLT, high fever and increased ascites followed by poor bile drainage was accompanied by elevation of serum liver enzymes. Liver biopsy showed occlusion of the central veins by fibro-edematous endothelium and submassive necrosis of the parenchyma. Veno-occlusive disease (VOD) was suspected, and re-LDLT was urgently performed because of deterioration of hepatic failure. There are few cases of VOD after liver transplantation and this is the first one in an infant after LDLT.
Izaki
Toshiya
T
Department of Pediatric Surgery, Kumamoto University Hospital, Kumamoto, Japan.
Inomata
Yukihiro
Y
Asonuma
Katsuhiro
K
Okajima
Hideaki
H
Ohshiro
Hajime
H
Ueno
Mikako
M
Hamamoto
Rieko
R
Iyama
Ken-Ichi
K
Tanaka
Koichi
K
D006083:Graft Occlusion, Vascular / Q000473:pathology*; D006504:Hepatic Veno-Occlusive Disease / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007223:Infant; D008099:Liver / Q000473:pathology; D016031:Liver Transplantation / Q000009:adverse effects*; D019520:Living Donors; D008297:Male