Giant cell malignant fibrous histiocytoma of the breast: a case report.
A case of primary malignant fibrous histiocytoma of the breast is reported. The patient was a 48-yr-old woman with a huge tumor involving almost the entire left breast. The central portion of her left breast was already rotted by extensive necrosis and inflammation. She was treated by radical mastectomy and axillary lymphadenectomy to level I. Pathologic examination supported by an immunohistochemical staining confirmed the tumor as malignant fibrous histiocytoma of giant cell type. Axillary lymph nodes were free from tumor metastasis. She had not taken any postoperative adjuvant therapy. The metastasis to lungs was found 2 months after the operation, and she died within 6 months.
Oh
Se Jeong
SJ
Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea. ohsj@olmh.cuk.ac.kr
Kim
Kyoung Mee
KM
Hong
Tae Ho
TH
Park
Woo Chan
WC
Kim
Jeong Soo
JS
Jung
Sang Seol
SS
D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D005260:Female; D015726:Giant Cells / Q000473:pathology*; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis* / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary; D008875:Middle Aged; D009236:Myxosarcoma / Q000175:diagnosis / Q000473:pathology; D009336:Necrosis; D009362:Neoplasm Metastasis; D012509:Sarcoma / Q000175:diagnosis / Q000473:pathology