Catalytic beacons for the detection of DNA and telomerase activity.
DNA and telomerase activity are detected by a DNAzyme generated upon hybridization and opening of a functional catalytic beacon.
Xiao
Yi
Y
The Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Pavlov
Valeri
V
Niazov
Tamara
T
Dishon
Arnon
A
Kotler
Moshe
M
Willner
Itamar
I
D002384:Catalysis; D002452:Cell Count; D004247:DNA / Q000032:analysis* / Q000378:metabolism; D021881:DNA, Catalytic / Q000737:chemistry / Q000378:metabolism; D004789:Enzyme Activation; D006367:HeLa Cells; D006801:Humans; D015336:Molecular Probe Techniques; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization; D009696:Nucleic Acids / Q000737:chemistry*; D010777:Photochemistry; D012680:Sensitivity and Specificity; D019098:Telomerase / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism*; D013997:Time Factors
D021881:DNA, Catalytic; D009696:Nucleic Acids; D004247:DNA; D019098:Telomerase