Prognostic significance of serum creatinine concentration for in-hospital mortality in patients with acute myocardial infarction who underwent successful primary percutaneous coronary intervention (from the Heart Institute of Japan Acute Myocardial Infarction [HIJAMI] Registry).
This study evaluated the impact of serum creatinine levels on in-hospital mortality in 1,359 consecutive patients with acute myocardial infarction (from a Japanese prospective multicenter registry) who underwent successful primary percutaneous coronary intervention (PCI). Even in the patients who underwent successful primary PCI, the in-hospital mortality of patients with mild (1.2 </= creatinine < 2.0 mg/dl) and severe (creatinine >/=2.0 mg/dl) renal dysfunction was greater (17.1% and 34.5%, respectively) than that of patients without renal dysfunction (3.9%) (relative risk [RR] 1.72, 95% confidence interval [CI] 0.94 to 3.14, p = 0.080; and RR 4.26, 95% CI 1.48 to 12.27, p <0.0001, respectively).
Yamaguchi
Jun-ichi
J
Department of Cardiology, The Heart Institute of Japan, Tokyo Women's Medical University, Tokyo, Japan. junichi.yamaguchi@nifty.com
Kasanuki
Hiroshi
H
Ishii
Yasuhiro
Y
Yagi
Masahiro
M
Ogawa
Hiroshi
H
Fujii
Shin-ya
SY
Koganei
Hiroshi
H
Okada
Hisayuki
H
Kimura
Hirotaka
H
Horie
Toshinobu
T
Haze
Kazuo
K
Sumiyoshi
Tetsuya
T
Honda
Takashi
T
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D015331:Cohort Studies; D003404:Creatinine / Q000097:blood*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007564:Japan; D007676:Kidney Failure, Chronic / Q000097:blood / Q000150:complications; D008297:Male; D015337:Multicenter Studies as Topic; D009203:Myocardial Infarction / Q000097:blood* / Q000401:mortality* / Q000628:therapy; D011237:Predictive Value of Tests; D011379:Prognosis; D011446:Prospective Studies; D012042:Registries
D003404:Creatinine