Different treatments and outcomes of consecutive patients with non-ST-elevation myocardial infarction depending on initial electrocardiographic changes (results of the Acute Coronary Syndromes [ACOS] Registry).
Of 6,302 consecutive patients with acute non-ST-elevation myocardial infarction, 42.8% presented with ST depression, 31.9% showed no significant electrocardiographic changes, and 25.3% presented with T inversion. In comparison with patients with T inversion or no significant electrocardiographic changes, patients with ST depression more often had 3-vessel coronary disease, received less acute therapy despite a strong benefit in a subgroup analysis, and had a worse clinical outcome even after adjustment in a multivariate analysis. Patients with T inversion received a high rate of acute therapy and had a better outcome than did patients without significant electrocardiographic changes and patients with ST depression.
Wienbergen
Harm
H
Herzzentrum Ludwigshafen, Ludwigshafen, Germany. harmwnbrgn@aol.com
Gitt
Anselm Kai
AK
Schiele
Rudolf
R
Juenger
Claus
C
Heer
Tobias
T
Vogel
Christina
C
Gottwik
Martin
M
Senges
Jochen
J
D000319:Adrenergic beta-Antagonists; D000367:Age Factors; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000706:statistics & numerical data; D000806:Angiotensin-Converting Enzyme Inhibitors; D001241:Aspirin / Q000627:therapeutic use; D000077144:Clopidogrel; D003327:Coronary Disease / Q000503:physiopathology; D003331:Coronary Vessels / Q000473:pathology; D004363:Drug Utilization / Q000706:statistics & numerical data; D004562:Electrocardiography; D005260:Female; D005858:Germany; D017052:Hospital Mortality; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D008297:Male; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000401:mortality / Q000503:physiopathology* / Q000628:therapy*; D010043:Outcome and Process Assessment, Health Care; D010975:Platelet Aggregation Inhibitors; D012008:Recurrence; D012042:Registries; D013318:Stroke Volume / Q000502:physiology; D013988:Ticlopidine / Q000031:analogs & derivatives*; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000503:physiopathology
D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin