title: [Probiotics in inflammatory bowel disease: controlled trials and perspectives].
abstract: Probiotics may modulate intestinal flora and immunity and are therefore studied in an attempt to modulate experimental colitis or human inflammatory bowel disease. We analysed randomised controlled trials performed using probiotics in humans with Crohn's disease, ulcerative colitis and pouchitis. Perspectives include the use of genetically modified micro-organisms to deliver anti-inflammatory agents to the gastrointestinal tract.
authors.affiliation: Service de Gastro-Entérologie, Hôpital Européen Georges Pompidou, Paris, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Seksik
authors.forename: Philippe
authors.initials: P
authors.lastname: Marteau
mesh_terms: D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy* / Q000382:microbiology; D019936:Probiotics / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic
chemical_list: D000893:Anti-Inflammatory Agents