title: Allergen sensitization to aeroallergens including Blomia tropicalis among adult and childhood asthmatics in Thailand.
abstract: To study prevalence of allergen sensitization among asthmatics in Thailand, skin prick tests (SPT) were performed in 84 pediatric, 71 adult asthmatics and 71 adult volunteers. Allergen extracts used for testing included common allergens in Thailand and in Singapore. The incidence of positive SPT to any allergen among the three groups (childhood, adult patients and adult controls) were 64.3%, 43.7% and 35.2%, respectively. Dermatophagoides were the most common allergens sensitized by both pediatric (58.3%) and adult asthmatics (40.8%). Twenty-four children (28.6%) and 8 adult patients (11.3%) were sensitized to storage mites (Blomia tropicalis and/or Austroglyciphagus malaysiensis). All patients sensitized to Blomia tropicalis were sensitized to Dermatophagoides. Twenty-seven percent and 15.5% of childhood and adult asthmatics were sensitized to cockroach allergens. The rates of sensitization to oil palm pollen in childhood and adult asthmatics were 8.3% and 5.6%, respectively. Sensitization to other pollens and spores were less than 5%. This study confirms the importance of Dermatophagoides among Thai asthmatics.
authors.affiliation: Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Tassalapa
authors.initials: T
authors.lastname: Daengsuwan
authors.forename: Bee-Wah
authors.initials: BW
authors.lastname: Lee
authors.forename: Nualanong
authors.initials: N
authors.lastname: Visitsuntorn
authors.forename: Suchai
authors.initials: S
authors.lastname: Charoenratanakul
authors.forename: Sirirat
authors.initials: S
authors.lastname: Ruangrak
authors.forename: Orathai
authors.initials: O
authors.lastname: Jirapongsananuruk
authors.forename: Pakit
authors.initials: P
authors.lastname: Vichyanond
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000397:Air Pollution; D000485:Allergens / Q000009:adverse effects* / Q000276:immunology*; D000818:Animals; D039741:Antigens, Dermatophagoides / Q000009:adverse effects / Q000276:immunology; D001249:Asthma / Q000453:epidemiology / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D003058:Cockroaches / Q000276:immunology; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D008925:Mites / Q000276:immunology; D015995:Prevalence; D012882:Skin Tests; D013785:Thailand / Q000453:epidemiology
chemical_list: D000485:Allergens; D039741:Antigens, Dermatophagoides