Molecular characterization and phylogenetic study of newcastle disease virus isolates from recent outbreaks in eastern Uganda.
Newcastle disease virus isolates from chickens in eastern Uganda in 2001 were found to be velogenic by fusion protein cleavage site sequence analysis and biological characterization; the intracerebral pathogenicity index was 1.8. Analysis of their hemagglutinin-neuraminidase protein gene sequences revealed a novel genotype unrelated to those that caused previous outbreaks.
Otim
Maxwell O
MO
Livestock Health Research Institute, P.O. Box 96, Tororo, Uganda. Maxwell_ot@yahoo.com
Christensen
Henrik
H
Jørgensen
Poul H
PH
Handberg
Kurt J
KJ
Bisgaard
Magne
M
D000595:Amino Acid Sequence; D000818:Animals; D002645:Chickens; D004196:Disease Outbreaks; D015707:HN Protein / Q000235:genetics; D008969:Molecular Sequence Data; D009521:Newcastle Disease / Q000453:epidemiology / Q000821:virology*; D009522:Newcastle disease virus / Q000145:classification* / Q000235:genetics; D010802:Phylogeny; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014454:Uganda / Q000453:epidemiology
D015707:HN Protein