The treatment of nonepileptic seizures: historical perspectives and future directions.
Nonepileptic seizures (NES) are neuropsychiatric disorders presenting with a combination of neurologic signs and underlying psychological conflicts. For more than a century, the medical community has accumulated data and insights about the phenomenology, epidemiology, risks, comorbidities, and prognosis of NES. However, we have not progressed much beyond anecdotal reports of treatments for NES, and no randomized, controlled trials of treatment for the disorder have been conducted. We review the diagnosis and treatment of NES and suggest directions for future research in these areas.
LaFrance
W Curt
WC
Brown Medical School, Rhode Island Hospital, Departments of Psychiatry and Neurology, Providence, Rhode Island 02903, USA. William_LaFrance_Jr@Brown.edu
Devinsky
Orrin
O
D000927:Anticonvulsants / Q000266:history / Q000627:therapeutic use; D003131:Combined Modality Therapy / Q000266:history / Q000379:methods / Q000639:trends; D003291:Conversion Disorder / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy; D005544:Forecasting; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D008962:Models, Theoretical; D011613:Psychotherapy / Q000266:history / Q000639:trends; D012640:Seizures / Q000175:diagnosis / Q000266:history* / Q000628:therapy*; D013001:Somatoform Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy; D016896:Treatment Outcome
D000927:Anticonvulsants