Synthesis and in vitro antifungal activity of 4-substituted phenylguanidinium salts.
A series of 4-substituted phenylguanidinium derivatives was synthesized and its antimicrobial activity was evaluated in vitro against eight potentially pathogenic strains of fungi.
Braunerová
Gabriela
G
Department of Inorganic and Organic Chemistry, Faculty of Pharmacy, Charles University, Heyrovského 1203, Hradec Králové 500 05, Czech Republic.
Buchta
Vladimír
V
Silva
Luis
L
Kunes
Jirí
J
Palát
Karel
K
D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D018153:Czech Republic; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005658:Fungi / Q000145:classification / Q000187:drug effects; D006146:Guanidines / Q000138:chemical synthesis* / Q000145:classification / Q000494:pharmacology*; D007536:Isomerism; D008826:Microbial Sensitivity Tests / Q000379:methods; D008956:Models, Chemical
D000935:Antifungal Agents; D006146:Guanidines; C026943:phenylguanidine