ADHD and sleep in homicidal men with antisocial personality disorder.
A history of attention deficit hyperactivity disorder (ADHD) is commonly found in subjects with antisocial personality disorder (ASP). Besides ASP, childhood ADHD also predicts drug abuse disorders and criminal activity in adulthood. Childhood ADHD and ASP appear to be the only psychiatric disorders reported to be associated with an increase in deep sleep. The aims of the present study were to retrospectively measure the childhood ADHD of habitually violent men with ASP and Cloninger type 2 alcoholism, and to characterize the possible relationship between childhood ADHD and sleep architecture in these men. The subjects of the study consisted of 14 homicidal offenders recruited from a forensic psychiatric examination. Ten age- and gender-matched healthy volunteers served as controls. Childhood ADHD symptoms were measured using the Wender-Utah Rating Scale (WURS). The main findings were that violent offenders with ASP had significantly higher mean WURS scores compared with controls, and both the absolute and percentage amount of stage 4 sleep as well as delta and theta powers in this sleep stage were positively correlated with the WURS scores. The present study supports the idea that childhood ADHD is associated with the abnormal sleep architecture in habitually violent men with ASP. These two disorders seem to share, at least partly, the same central nervous system deficit.
Lindberg
Nina
N
Department of Psychiatry, University of Helsinki, Helsinki, Finland. nina.lindberg@pp3.inet.fi
Tani
Pekka
P
Porkka-Heiskanen
Tarja
T
Appelberg
Björn
B
Rimón
Ranan
R
Virkkunen
Matti
M
D000293:Adolescent; D000328:Adult; D000987:Antisocial Personality Disorder / Q000150:complications* / Q000523:psychology*; D001289:Attention Deficit Disorder with Hyperactivity / Q000150:complications / Q000523:psychology*; D016022:Case-Control Studies; D006708:Homicide / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D012893:Sleep Wake Disorders / Q000523:psychology*