Antenatal necrotic injury in severe twin-to-twin transfusion syndrome. A case and review.
A case of twin-to-twin transfusion syndrome (TTTS) was associated with ischemic injury of the left leg of the recipient twin. Five reduction amniocenteses were performed between 17 6/7 and 23 3/7 weeks followed by fetoscopic laser ablation of chorioangiopagus vessels at 23 6/7 weeks of gestation. Anatomic assessment of the affected limb indicated timing of the injury at 19 4/7 weeks gestational age. The published literature suggests that ischemic fetal injuries in severe TTTS are associated with blood hyperviscosity in the affected twin.
Carr
Stephen R
SR
Division of Maternal-Fetal Medicine, Women and Infants' Hospital and The Program in Fetal Medicine, Hasbro Children's Hospital and The Program in Fetal Medicine, Brown University, Providence, RI 02905, USA. SCarr@wihri.org
Luks
François
F
Tracy
Thomas
T
Plevyak
Michael
M
D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D005330:Fetofetal Transfusion / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007511:Ischemia / Q000150:complications / Q000175:diagnosis*; D007866:Leg / Q000098:blood supply* / Q000473:pathology*; D009336:Necrosis / Q000150:complications / Q000175:diagnosis; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000706:statistics & numerical data*