title: [Immunobiological properties of 100 years old Bacillus anthracis vaccine strains Lange].
abstract: The results of the study of B. anthracis vaccine strains Lange 1 and 2 in the form of spores after prolonged storage in 30% glycerine solution at room temperature are presented. The study revealed that spores stored for 100 years germinated and bacterial cells proved to be viable when cultivated in artificial nutrient media and in vivo. They exhibited typical cultural, morphological, biochemical, virulent, antigenic and immunogenic properties.
authors.affiliation: Academy of Veterinary Medicine, Kazan, Republic of Tatarstan, Russia.
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Sheremet'eva
authors.forename: R G
authors.initials: RG
authors.lastname: Gosmanov
authors.forename: K M
authors.initials: KM
authors.lastname: Salmakov
authors.forename: N R
authors.initials: NR
authors.lastname: Gosmanov
mesh_terms: D000818:Animals; D000881:Anthrax / Q000821:virology*; D001408:Bacillus anthracis / Q000472:pathogenicity / Q000502:physiology*; D001428:Bacterial Vaccines / Q000032:analysis*; D004356:Drug Storage / Q000706:statistics & numerical data*; D005990:Glycerol; D006168:Guinea Pigs; D051379:Mice; D013171:Spores, Bacterial / Q000254:growth & development; D013696:Temperature; D013997:Time Factors; D014774:Virulence
chemical_list: D001428:Bacterial Vaccines; D005990:Glycerol