title: [Microbiological characteristics and clinical efficacy of phosphomycin].
abstract: E. coli is the most frequent agent causing urinary infection (UI) both in adults and children. E. coli of UI outpatients is often resistant to ampicilline, amoxicilline and co-trimoxasol. The study of phosphomycin in UI outpatients showed its highest efficacy against E. coli. Phosphomycin in a single daily dose of 3 g is a drug of choice in acute uncomplicated cystitis. The results of the study also demonstrate that phosphomycin can be used for prevention of pyoinflammatory complications before endoscopic manipulations and operations as well as open operations on the lower urinary tracts and genital organs.
authors.forename: O B
authors.initials: OB
authors.lastname: Loram
authors.forename: L S
authors.initials: LS
authors.lastname: Strachunskiĭ
authors.forename: L A
authors.initials: LA
authors.lastname: Siniakova
authors.forename: V V
authors.initials: VV
authors.lastname: Rafal'skiĭ
authors.forename: A N
authors.initials: AN
authors.lastname: Shevelev
authors.forename: I V
authors.initials: IV
authors.lastname: Kosova
mesh_terms: D000328:Adult; D001437:Bacteriuria / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D002648:Child; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics; D004927:Escherichia coli Infections / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D005578:Fosfomycin / Q000008:administration & dosage*; D005836:Genitalia, Female / Q000382:microbiology / Q000473:pathology; D005837:Genitalia, Male / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D014551:Urinary Tract / Q000382:microbiology / Q000473:pathology
chemical_list: D005578:Fosfomycin