[Effect of fast-acting spray for heat stroke in enhancing heat tolerance of rats].
OBJECTIVE
To observe the effect of fast-acting spray for heat stroke, a preparation of traditional Chinese drugs, in enhancing the heat tolerance in rats.


METHODS
Thirty SD rats were randomized into 3 groups(with 10 in each group), and group A was treated with the fast-acting spray for heat stroke, group B with chlorpromazine, and group C with cool boiled water, before they were exposed to heat at 41 degrees Celsius in a heat chamber with relative humidity of 70% till death. The rats' rectal temperature was measured before and 1 h after the heat exposure, and the time when death occurred in the rats was recorded.


RESULTS
In comparison with group C, the rats in groups A and B had lower rectal temperature and prolonged survival time with decrease mortality.


CONCLUSIONS
The fast-acting spray for heat stroke we prepared may enhance the heat tolerance of rats.
Wang
Wei
W
Research Laboratory of New Traditional Chinese Medicine, Department of Traditional Chinese Medicine, First Military Medical University, Guangzhou 510515, China.
Tan
Xiao-mei
XM
Liu
Guo-qing
GQ
D000818:Animals; D001831:Body Temperature; D005260:Female; D018883:Heat Stroke / Q000401:mortality / Q000517:prevention & control*; D008297:Male; D008516:Medicine, Chinese Traditional; D051381:Rats