title: Plexiform fibrohistiocytic tumor.
abstract: We report the case of a 6-year-old Japanese boy with a plexiform fibrohistiocytic tumor on the right perioral region. Clinically, the tumor, 5 mm in diameter, was a solitary, hard, erythematous, slowly growing, painless nodule. There was no preceding trauma. Histology revealed a well-circumscribed plexiform lesion with a biphasic appearance. Immuno-histochemistry demonstrated CD68 positivity in many of mononuclear macrophages. The lesion was negative for S-100 protein, lysozyme, CD57 and factor XIIIa. Interestingly, the tumor showed an intradermal location from superficial to deep dermis, and lacked osteoclast-like giant cells. During the follow-up for 9 months after the resection, there was no recurrence or metastasis.
authors.affiliation: Department of Dermatology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Mori
authors.forename: Takashi
authors.initials: T
authors.lastname: Hashimoto
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D005153:Facial Neoplasms / Q000737:chemistry / Q000473:pathology*; D018219:Histiocytoma, Benign Fibrous / Q000737:chemistry / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology*