title: European reference values for Doppler indices of left ventricular diastolic filling.
abstract: The European Study Group on diastolic heart failure requires objective evidence of abnormal left ventricular diastolic function to establish the diagnosis of diastolic heart failure, which is common in older people. Reference values for Doppler indices of transmitral flow, used to assess left ventricular diastolic function, have not been reported for people 70 years and over in Europe. The aim of this study was to establish reference values for these Doppler indices of transmitral flow in older people. A random sample of 355 subjects aged 70 and over, living in the community underwent clinical assessment and echocardiography. Asymptomatic subjects with no cardiovascular disease and cardiovascular risk factors were identified. Measurements of five commonly used Doppler indices of transmitral flow from these subjects were obtained and reference range expressed as mean+/-2 standard deviations and as percentiles. We have therefore generated reference Doppler values of transmitral flow for people aged over 70 in a British population.
authors.affiliation: Department of Geriatric Medicine, University of Wales College of Medicine, Llandough Hospital, Penarth, UK.
authors.forename: M F Victor
authors.initials: MF
authors.lastname: Sim
authors.forename: Shu F
authors.initials: SF
authors.lastname: Ho
authors.forename: M Sinead
authors.initials: MS
authors.lastname: O'Mahony
authors.forename: John A
authors.initials: JA
authors.lastname: Steward
authors.forename: Maurice
authors.initials: M
authors.lastname: Buchalter
authors.forename: Michael
authors.initials: M
authors.lastname: Burr
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D003971:Diastole / Q000502:physiology; D015150:Echocardiography, Doppler; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D012016:Reference Values; D012720:Severity of Illness Index; D013599:Systole / Q000502:physiology; D014664:Vasodilation / Q000502:physiology; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000503:physiopathology; D016277:Ventricular Function, Left / Q000502:physiology*; D014852:Wales / Q000453:epidemiology