title: [Search of promising strains of bifidobacteria and lactobacillus for the development of new biopreparations].
abstract: For the first time the species composition of bifidobacteria and lactobacilli in clinically healthy young children has been studied. As revealed in this study, the dominating species of bifidobacteria are B. longum, B. adolescentis and B. infantis, while the dominating species of lactobacilli are Lactobacillus acidophilus and L. rhamnosus. In 83 isolated cultures of bifidobacteria and 34 isolated species of lactobacilli the activity of acid formation and the antagonistic activity with respect to Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Enterococcus faecalis, Clostridium perfringens have been tested. B. longum strain 58B, B. infantis strain 37B, L. rhamnosus strain 12L and L. acidophilus strain 27L, typical for children of this age group, having good antagonistic activity and pronounced acid-forming properties, have been selected. These strains hold good promise to be used as the basis for the development of a complex probiotic preparation for correcting intestinal microflora in young children.
authors.affiliation: State Medical University, Institute of Medico-Social Rehabilitology, Moscow, Russia.
authors.forename: E A
authors.initials: EA
authors.lastname: Postnikova
authors.forename: B A
authors.initials: BA
authors.lastname: Efimov
authors.forename: N N
authors.initials: NN
authors.lastname: Volodin
authors.forename: L I
authors.initials: LI
authors.lastname: Kafarskaia
mesh_terms: D000143:Acids / Q000378:metabolism; D000898:Antibiosis; D003016:Clostridium perfringens / Q000502:physiology; D004755:Enterobacteriaceae / Q000502:physiology; D005260:Female; D006095:Gram-Positive Cocci / Q000502:physiology; D006801:Humans; D007223:Infant; D007778:Lactobacillus / Q000302:isolation & purification* / Q000378:metabolism; D008297:Male; D019936:Probiotics / Q000302:isolation & purification* / Q000378:metabolism; D013045:Species Specificity
chemical_list: D000143:Acids