title: lga972: a cross-platform application for optimizing LD studies using a genetic algorithm.
abstract: lga972 is a user-friendly cross-platform application with a graphical interface for determining the design features of two-stage genetic linkage disequilibrium studies that minimize the genotyping burden.
authors.affiliation: Virginia Institute for Psychiatric and Behavioral Genetics, Medical College of Virginia of Virginia Commonwealth University, Richmond, VA 23298-0126, USA. jrobles@vcu.edu
authors.forename: Jaime R
authors.initials: JR
authors.lastname: Robles
authors.forename: Edwin J C G
authors.initials: EJ
authors.lastname: van den Oord
mesh_terms: D000465:Algorithms; D002874:Chromosome Mapping / Q000379:methods*; D003196:Computer Graphics; D004252:DNA Mutational Analysis / Q000379:methods; D005838:Genotype; D016247:Information Storage and Retrieval / Q000379:methods*; D015810:Linkage Disequilibrium / Q000235:genetics*; D008957:Models, Genetic; D015203:Reproducibility of Results; D012107:Research Design; D018401:Sample Size; D012680:Sensitivity and Specificity; D012984:Software; D014584:User-Computer Interface