title: Results of video-assisted thoracic surgery for stage I/II non-small cell lung cancer.
abstract: OBJECTIVE
  The best indicators for VATS are not well known. Therefore, we review here a series of patients who underwent VATS lobectomy and segmentectomy at our hospital, and we attempt to identify the factors that influence the survival of VATS patients and the backgrounds of such patients.
  
  
  METHODS
  A thoracoscopic curative approach was attempted in 140 patients (100 lobectomy, 40 segmentectomy) from January 1994 to December 2002. We retrospectively reviewed the VATS patients with non-small cell lung cancer (NSCLC). All patients were subject to lobectomy or segmentectomy, including dissection of hilar and mediastinal lymph nodes that were in pathological stage (p-Stage) I or II. Our VATS approach was a hybrid technique, employing three ports and a small (7 cm diameter) utility thoracotomy to allow access for the instrument and a view.
  
  
  RESULTS
  The Kaplan-Meier probabilities of survival at 5 years were VATS, 77.3%. According to a univariate analysis of survival curves, the significant prognostic factors (P < 0.05) in the patients with VATS in p-Stage I and II were gender, type of histology, and T factor. In addition, the grades of differentiation, surgical procedure (lobectomy vs. segmentectomy), and extent of metastasis to the hilar lymph node (N0 vs. N1) in VATS were not found to be significant prognostic factors. A multivariate prognostic factor in VATS showed that the histologic cell type, gender, and T factor were predominant. All of the VATS cases that included these three favorable factors (adenocarcinoma, T1, female) were alive.
  
  
  CONCLUSIONS
  Stringent selection of candidates for VATS in NSCLC at pathological stages I and II could be an acceptable and valuable approach.
authors.affiliation: Second Department of Surgery, School of Medicine, Fukuoka University, 45-1, 7-chome Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan. akinori@fukuoka-u.ac.jp
authors.forename: Akinori
authors.initials: A
authors.lastname: Iwasaki
authors.forename: Takayuki
authors.initials: T
authors.lastname: Shirakusa
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shiraishi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yamamoto
mesh_terms: D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D018579:Patient Selection; D011013:Pneumonectomy / Q000379:methods; D011379:Prognosis; D012189:Retrospective Studies; D016019:Survival Analysis; D020775:Thoracic Surgery, Video-Assisted / Q000379:methods*; D016896:Treatment Outcome