The "fatty pancreas allograft": anatomopathologic findings and clinical experience.
Thirty-three hematoxylin and eosin-stained sections from 7 turned down pancreata from donors with body mass index (BMI) of 33.3 (range, 28-42) were examined. There was more fat infiltration between the superficial pancreatic lobules, interspersed with superficial islands of pancreatic tissue with its vessels and ductules. Thicker fatty interlobular septa were observed with numerous intralobular fat vacuoles. One organ had widespread autolysis. No microthrombi were noted. One pancreas from a 24-year-old donor with BMI of 30 was transplanted successfully. The "fatty pancreas" can be defatted and used for transplantation.
Nghiem
D D
DD
Department of Surgery, Allegheny General Hospital, Pittsburgh, Pennsylvania 15212, USA.
Olson
P R
PR
Ormond
D
D
D000328:Adult; D015992:Body Mass Index; D001926:Brain Death; D002102:Cadaver; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000473:pathology*; D016035:Pancreas Transplantation / Q000473:pathology / Q000502:physiology*; D010182:Pancreatic Diseases; D012189:Retrospective Studies; D014019:Tissue Donors; D016896:Treatment Outcome