title: Increased left ventricular mass in obese adolescents.
abstract: OBJECTIVE
  An increase of left ventricular mass (LVM) has been reported in obese adolescents in previous studies using echocardiography. The aim of our study was to determine the extent of the increase in LVM and correlation to other risk factors using cardiac magnetic resonance imaging in obese and lean adolescents.
  
  
  RESULTS
  Nineteen obese and 20 lean adolescents were recruited. Following resting blood pressure measurements and blood sampling for insulin, triglycerides, and cholesterol levels, all subjects underwent cardiac magnetic resonance examination to assess LVM. LVM adjusted for body height was 16% greater in obese compared to lean adolescents (median 66 g/m, p = 0.0042). Obese subjects had higher resting systolic blood pressures than controls (median 115 vs. 110 mmHg, p = 0.0077) and higher fasting triglyceride and insulin levels. HDL-cholesterol levels were lower in the obese group compared with the lean group.
  
  
  CONCLUSIONS
  Obese adolescents had a higher LVM than age-matched lean subjects, which correlated mainly with body mass index and systolic blood pressure. These findings add to the established cardiovascular risk profile of obese adolescents.
authors.affiliation: Department of Clinical Physiology, Sahlgrenska Academy at Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden. fribergp@mednet.gu.se
authors.forename: P
authors.initials: P
authors.lastname: Friberg
authors.forename: A
authors.initials: A
authors.lastname: Allansdotter-Johnsson
authors.forename: A
authors.initials: A
authors.lastname: Ambring
authors.forename: R
authors.initials: R
authors.lastname: Ahl
authors.forename: H
authors.initials: H
authors.lastname: Arheden
authors.forename: J
authors.initials: J
authors.lastname: Framme
authors.forename: A
authors.initials: A
authors.lastname: Johansson
authors.forename: D
authors.initials: D
authors.lastname: Holmgren
authors.forename: H
authors.initials: H
authors.lastname: Wåhlander
authors.forename: S
authors.initials: S
authors.lastname: Mårild
mesh_terms: D000293:Adolescent; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology; D017379:Hypertrophy, Left Ventricular / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D007328:Insulin / Q000097:blood; D018810:Magnetic Resonance Angiography; D008297:Male; D009765:Obesity / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D014280:Triglycerides / Q000097:blood
chemical_list: D007328:Insulin; D014280:Triglycerides