title: Medullary thyroid carcinoma associated with hyperthyroidism: a case report and review of the literature.
abstract: Thyroid cancer is occasionally associated with hyperthyroidism. Papillary thyroid carcinoma is the most frequently reported histologic type followed by follicular thyroid carcinoma. Medullary thyroid carcinoma (MTC) has been rarely described in association with Graves' disease or other forms of hyperthyroidism. To our knowledge, only 14 cases have been described in which MTC was associated with hyperthyroidism. We report a 70-year-old male who had a clinically significant MTC discovered in the course of diagnostic work-up for hyperthyroidism. We also summarize the clinical features of the other 14 reported cases.
authors.affiliation: Joint Baylor College of Medicine and MD Anderson Cancer Center Fellowship Program, Houston, Texas, USA.
authors.forename: Mouhammed Amir
authors.initials: MA
authors.lastname: Habra
authors.forename: Rabih
authors.initials: R
authors.lastname: Hijazi
authors.forename: Gordana
authors.initials: G
authors.lastname: Verstovsek
authors.forename: Marco
authors.initials: M
authors.lastname: Marcelli
mesh_terms: D000368:Aged; D044963:Biopsy, Fine-Needle; D018276:Carcinoma, Medullary / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy; D008297:Male; D011877:Radionuclide Imaging; D016896:Treatment Outcome