title: Evolutionary genomics: yeasts accelerate beyond BLAST.
abstract: Two new genome sequences confirm that a whole genome duplication occurred in an ancestor of Saccharomyces cerevisiae. This left a legacy of about 500 pairs of duplicated genes, many of which contribute to this yeast's ability to ferment glucose anaerobically; a few have been evolving so quickly they retain almost no sequence similarity to each other.
authors.affiliation: Department of Genetics, Smurfit Institute, University of Dublin, Trinity College, Dublin 2, Ireland. khwolfe@tcd.ie
authors.forename: Ken
authors.initials: K
authors.lastname: Wolfe
mesh_terms: D001483:Base Sequence; D030541:Databases, Genetic; D019143:Evolution, Molecular; D023061:Gene Order; D020131:Genes, Duplicate / Q000235:genetics*; D014644:Genetic Variation; D016681:Genome, Fungal; D010802:Phylogeny; D011123:Polyploidy; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D017385:Sequence Homology