Wavefront analysis of higher order aberrations in dry eye patients.
OBJECTIVE
To compare ocular wavefront aberrations of normal and dry eyes and to describe the characteristics of higher order aberration in dry eyes.


METHODS
Wavefront analysis of higher order ocular aberrations (total S3+4+5, spherical-like S4, coma-like S3+5) was performed with a Hartmann-Shack aberrometer in 20 dry eyes and 20 normal control eyes.


RESULTS
Total, spherical-like, and coma-like aberrations were significantly greater in dry eyes than in normal controls (P < .01) both for a 4-mm (total S3+4: factor of 2.58; spherical S4: factor of 2.50; coma S3: factor of 2.70) and 6-mm-diameter pupil (S3+4+5: factor of 2.29, S4: x2.53, and S3+5: factor of 2.40).


CONCLUSIONS
Eyes of dry eye patients showed greater optical aberrations compared with normal control eyes. Increase in higher order aberrations in dry eyes resulted from increased tear film irregularity.
Montés-Micó
Robert
R
Research, Development and Innovation Department, Ophthalmologic Institute of Alicante, School of Medicine, University Miguel Hernández, Spain. roberto.montes@uv.es
Cáliz
Araceli
A
Alió
Jorge L
JL
D000328:Adult; D016022:Case-Control Studies; D003316:Corneal Diseases / Q000503:physiopathology*; D019781:Corneal Topography; D015352:Dry Eye Syndromes / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D013666:Tears / Q000502:physiology; D014786:Vision Disorders / Q000503:physiopathology*