title: [Prospective study of systemic inflammatory response syndrome after cardiac surgery as a effective indicator].
abstract: This prospective study was designed to elucidate the meaning of systemic inflammatory response syndrome (SIRS), the mechanisms that lead to the protraction of SIRS, and whether SIRS is potentially a simple and effective postoperative indicator or not in patients who are operated on with cardiopulmonary bypass (CPB). We studied the duration of SIRS in 90 patients. Our data showed that 83 (92%) of the 90 patients met 2 or more criteria for SIRS and that significant relationship between the protraction of SIRS and the duration of aortic clamping time, CPB time, operation time, and the risk of postoperative organ damage and complication. Those results suggest that SIRS after cardiac surgery with CPB can be regarded as right criteria and highly valuable indexes of preparatory state of organ dysfunction.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Hiroshima Prefectural Hospital, Hiroshima, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Hirai
authors.forename: Y
authors.initials: Y
authors.lastname: Hamanaka
authors.forename: N
authors.initials: N
authors.lastname: Mitsui
authors.forename: M
authors.initials: M
authors.lastname: Isaka
authors.forename: M
authors.initials: M
authors.lastname: Sutoh
mesh_terms: D000328:Adult; D000368:Aged; D006348:Cardiac Surgical Procedures; D001026:Coronary Artery Bypass; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011446:Prospective Studies; D018746:Systemic Inflammatory Response Syndrome / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology