title: Intensive insulin therapy in type 1 and type 2 diabetes.
abstract: Intensive insulin regimens can produce substantial clinical benefits for patients with type 1 and type 2 diabetes, but they are associated with an increased incidence of hypoglycaemia. This article discusses such regimens and whether the risk of hypoglycaemia can be reduced by using the new basal insulin analogue, insulin glargine.
authors.affiliation: Bolton Diabetes Centre, Bolton BL1 4AL.
authors.forename: John
authors.initials: J
authors.lastname: Dean
authors.forename: Patrick
authors.initials: P
authors.lastname: Sharp
mesh_terms: D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D006801:Humans; D007003:Hypoglycemia / Q000517:prevention & control; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use*
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin