title: Microarray analysis and functional characterization of the nitrosative stress response in nonmucoid and mucoid Pseudomonas aeruginosa.
abstract: The type strain of Pseudomonas aeruginosa, PAO1, showed great upregulation of many nitrosative defense genes upon treatment with S-nitrosoglutathione, while the mucoid strain PAO578II showed no further upregulation above its constitutive upregulation of nor and fhp. NO* consumption however, showed that both strains mount functional, protein synthesis-dependent NO*-consumptive responses.
authors.affiliation: College of Pharmacy, Toxicology Program, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
authors.forename: Aaron M
authors.initials: AM
authors.lastname: Firoved
authors.forename: Simon R
authors.initials: SR
authors.lastname: Wood
authors.forename: Wojciech
authors.initials: W
authors.lastname: Ornatowski
authors.forename: Vojo
authors.initials: V
authors.lastname: Deretic
authors.forename: Graham S
authors.initials: GS
authors.lastname: Timmins
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D020869:Gene Expression Profiling; D018869:Heat-Shock Response; D006801:Humans; D009569:Nitric Oxide / Q000378:metabolism; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D011550:Pseudomonas aeruginosa / Q000235:genetics / Q000254:growth & development* / Q000502:physiology*; D026422:S-Nitrosoglutathione / Q000494:pharmacology*; D015854:Up-Regulation
chemical_list: D001426:Bacterial Proteins; D009569:Nitric Oxide; D026422:S-Nitrosoglutathione