Mouse genetic approaches to access pathways important in retinal function.
The laboratory mouse is a premier research tool for understanding human biology and disease. With the availability of the first complete draft sequences of the mouse genome and ongoing large scale screens for new mouse mutations to serve as novel models, the usefulness of the mouse will only increase. The vision research field, in particular, which has identified many human diseases for which no models are yet available, will benefit from the newly developed tools in mouse molecular genetics.
Nishina
Patsy M
PM
The Jackson Laboratory, Bar Harbor, ME 04609, USA. pmn@jax.org
Naggert
Jürgen K
JK
D000818:Animals; D004195:Disease Models, Animal; D008040:Genetic Linkage; D005821:Genetic Techniques; D006801:Humans; D051379:Mice; D009154:Mutation; D010641:Phenotype; D010786:Photoreceptor Cells; D012160:Retina / Q000503:physiopathology*; D012162:Retinal Degeneration / Q000235:genetics