title: Occlusion of pseudoaneurysms using human or bovine thrombin using contrast-enhanced ultrasound guidance.
abstract: Percutaneous thrombin occlusion of pseudoaneurysms complicating invasive coronary interventions has emerged as a useful therapeutic tool. To facilitate thrombin occlusion and make the procedure even more secure, preinjection of echo contrast medium during duplex ultrasound was tested in 132 patients. Complete and immediate occlusion of the pseudoaneurysm was achieved in 99.2% (131 of 132 patients). No complications related to the injection of thrombin were documented. Contrast-enhanced ultrasound-guided thrombin occlusion was a safe and effective therapeutic option. In aneurysms with complex morphology or multiple cavities, preinjection of contrast medium was helpful for documenting the flow pattern.
authors.affiliation: Clinic II (Cardiology/Angiology), Berufsgenossenschaftliche Kliniken Bergmannsheil Bochum, University of Bochum, Bochum, Germany. petergrewe@aol.com
authors.forename: Peter Hubert
authors.initials: PH
authors.lastname: Grewe
authors.forename: Andeas
authors.initials: A
authors.lastname: Mügge
authors.forename: Alfried
authors.initials: A
authors.lastname: Germing
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Harrer
authors.forename: Henning
authors.initials: H
authors.lastname: Baberg
authors.forename: Christoph
authors.initials: C
authors.lastname: Hanefeld
authors.forename: Thomas
authors.initials: T
authors.lastname: Deneke
mesh_terms: D017541:Aneurysm, False / Q000000981:diagnostic imaging* / Q000628:therapy*; D000818:Animals; D002417:Cattle; D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging*; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D013917:Thrombin / Q000008:administration & dosage*; D018615:Ultrasonography, Doppler, Color
chemical_list: D003287:Contrast Media; D006490:Hemostatics; D013917:Thrombin