Angiographic and volumetric intravascular ultrasound comparison between direct sirolimus-eluting stent implantation versus predilation.
Conventional sirolimus-eluting stent (SES) implantation typically follows balloon predilation. The impact of direct SES implantation on in-stent neointimal hyperplasia and the adjacent reference segments has not been evaluated. The aim of this study was to analyze direct and conventional SES implantation techniques by angiography and serial intravascular ultrasound. Fifty-three patients with single de novo coronary lesions underwent successful conventional (n = 26) and direct (n = 27) SES implantation. At 6-month follow-up, similar in-stent late luminal loss and decreased neointimal hyperplasia volume were seen in the 2 groups, preserving the luminal dimensions at the edges of the stents.
Muñoz
Juan S
JS
Institute Dante Pazzanese of Cardiology, São Paulo, Brazil.
Abizaid
Alexandre
A
Albertal
Mariano
M
Mintz
Gary S
GS
Graebin
Roselei
R
Feres
Fausto
F
Staico
Rodolfo
R
Mattos
Luiz A
LA
Tanajura
Luiz F
LF
Abizaid
Andrea S
AS
Sousa
Amanda
A
Sousa
J Eduardo
JE
D015906:Angioplasty, Balloon, Coronary; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D020123:Sirolimus / Q000008:administration & dosage*; D015607:Stents; D017539:Tunica Intima / Q000473:pathology; D018084:Ultrasonography, Interventional
D007166:Immunosuppressive Agents; D020123:Sirolimus