title: [Clinical effects of preoperative chemotherapy for Wilms tumor].
abstract: OBJECTIVE
  To evaluate the effects of preoperative chemotherapy for Wilms' tumor.
  
  
  METHODS
  Thirty-five surgically treated cases of Wilms tumor were retrospectively analyzed, 27 of which received preoperative chemotherapy.
  
  
  RESULTS
  After chemotherapy, the tumor volume reduced obviously in 17 cases and adverse effects of the chemotherapeutic agents occurred in 15 cases. Subsequent operation was performed in all the patients, of whom 1 died during the operation, 4 had delayed healing of the incisions and 5 still had decreased leucocytes.
  
  
  CONCLUSIONS
  Chemotherapy before the operation for Wilms tumor can effectively reduce the complications of the operation. Appropriate chemotherapy protocol and vigorous conservative drug therapy help prevent the occurrence of adverse effects and complications of the chemotherapy.
authors.affiliation: Department of Urology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
authors.forename: Yong-bin
authors.initials: YB
authors.lastname: Zhao
authors.forename: Shao-bin
authors.initials: SB
authors.lastname: Zheng
authors.forename: Xiang-ming
authors.initials: XM
authors.lastname: Mao
authors.forename: Hai-kuan
authors.initials: HK
authors.lastname: Zhou
authors.forename: Peng
authors.initials: P
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009396:Wilms Tumor / Q000628:therapy*