Highly enantioselective hetero-Diels-Alder reaction of Brassard diene with aromatic aldehydes.
[reaction: see text] Hetero-Diels-Alder reactions of Brassard diene with aromatic aldehydes were carried out smoothly in the presence of titanium(IV) tridentate Schiff base complexes to give the corresponding chiral delta-lactones in high enantioselectivities (up to 99% ee) under mild conditions.
Fan
Qian
Q
Key Laboratory of Green Chemistry & Technology Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China.
Lin
Lili
L
Liu
Jie
J
Huang
Yaozong
Y
Feng
Xiaoming
X
Zhang
Guolin
G