title: Scopulariopsis brevicaulis infection in a patient with acute myeloid leukemia.
abstract: Scopulariopsis brevicaulis is a soil fungus normally associated with onychomycosis. It causes subcutaneous infection in immunocompromised patients and is rarely isolated from blood. A case of systemic Scopulariopsis brevicaulis infection was reported in a patient with acute myeloid leukemia. The patient developed persistent fever that did not respond to wide spectrum antibiotics and amphotericin B. Scopulariopsis brevicaulis was the only pathogen isolated from blood cultures. The fever subsided with itraconazole and there was no recurrence of fungal infection with prolonged maintenance of oral itraconazole.
authors.affiliation: Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur.
authors.forename: K P
authors.initials: KP
authors.lastname: Ng
authors.forename: T S
authors.initials: TS
authors.lastname: Soo-Hoo
authors.forename: S L
authors.initials: SL
authors.lastname: Na
authors.forename: G G
authors.initials: GG
authors.lastname: Gan
authors.forename: J V
authors.initials: JV
authors.lastname: Sangkar
authors.forename: A K
authors.initials: AK
authors.lastname: Teh
mesh_terms: D000208:Acute Disease; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D006801:Humans; D016867:Immunocompromised Host; D017964:Itraconazole / Q000627:therapeutic use*; D007951:Leukemia, Myeloid / Q000150:complications*; D008297:Male; D009181:Mycoses / Q000188:drug therapy* / Q000382:microbiology*; D009894:Opportunistic Infections / Q000188:drug therapy* / Q000382:microbiology*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole