Cold shock response and adaptation at near-freezing temperature in microorganisms.
Microorganisms that naturally encounter sharp temperature shifts must develop strategies for responding and adapting to these shifts. Escherichia coli, which are adapted to living at both warm temperatures inside animals and cooler ambient temperatures, respond to low temperatures (10 degrees to 15 degrees C) by adjusting membrane lipid composition and increasing the production of proteins that act as "RNA chaperones" required for transcription and translation and proteins that facilitate ribosomal assembly. In contrast, yeast, which are adapted to cooler temperatures, show a relatively minor cold shock response after temperature shifts from 30 degrees to 10 degrees C but respond with a dramatic increase in the synthesis of trehalose and a heat shock protein when exposed to freezing or near-freezing temperatures. This emphasizes the fact that different groups of microorganisms exhibit distinct types of cold shock responses.
Inouye
Masayori
M
Robert Wood Johnson Medical School, Department of Biochemistry, 675 Hoes Lane, Piscataway, NJ 08854, USA. inouye@rwja.umdnj.edu
Phadtare
Sangita
S
D000222:Adaptation, Physiological / Q000502:physiology*; D000818:Animals; D001412:Bacillus subtilis / Q000502:physiology*; D003080:Cold Temperature; D004926:Escherichia coli / Q000502:physiology*; D005615:Freezing; D006801:Humans; D012441:Saccharomyces cerevisiae / Q000502:physiology*; D012769:Shock