title: [Respiratory epithelia in Wistar rats born in low frequency noise plus varying amounts of additional exposure].
abstract: Earlier studies of Wistar rat respiratory epithelia exposed to low frequency noise (LFN) (< or =500 Hz, including infrasound) showed that LFN effects trauma on the respiratory tract. In rats gestated and born in LFN environments, trauma was still treated in accordance with 86/609/EC. Respiratory epithelial fragments were prepared for light and scanning/transmission electron microscopy. Group A brush cell (BC) microvilli tended to group together; in Group B they were clearly clustered together, and in Groups C-F they became fused. Rosetta structures (rings of secretory cells centered on a BC) were visible in Groups A-D and difficult to identify in Groups E,F. The amount of sheared cilia increased with exposure time, as did the images of cellular de-differentiation. LFN exposure induces severe trauma on the respiratory epithelial cells in these rats.
authors.affiliation: Médico Anátomo-Patologista. Presidente do Conselho Científico. Centro da Performance Humana, Alverca do Ribatejo.
authors.forename: Nuno A A
authors.initials: NA
authors.lastname: Castelo Branco
authors.forename: Emanuel
authors.initials: E
authors.lastname: Monteiro
authors.forename: António
authors.initials: A
authors.lastname: Costa e Silva
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Reis Ferreira
authors.forename: Mariana
authors.initials: M
authors.lastname: Alves-Pereira
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D000013:Congenital Abnormalities / Q000209:etiology*; D005260:Female; D018811:Maternal Exposure; D009622:Noise / Q000009:adverse effects*; D051381:Rats; D017208:Rats, Wistar; D020545:Respiratory Mucosa / Q000648:ultrastructure*; D013997:Time Factors