[Neurotensin: physiological properties and role in the regulation of organism function].
In review one can find summarized data about neurotensin structure, properties and physiological activity, presented in publications of last 30 years, from the time when this peptide has been discovered. The article contains data about neurotensin blood plasma level and its distribution in various organs and tissues in humans and different animal species. Main manifestations of neurotensin physiological activity are discussed as its participation in regulation of cardiovascular, digestive and endocrine systems and also in regulation of immunity and cell growth. From clinical point of view, obvious interest represents neurotensin ability to produce neuroleptical and antipsychotie effects after injecting into the brain ventricles.
Osadchiĭ
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School of Physiology, Wits University, Johannesburg, South Africa.
D000595:Amino Acid Sequence; D000818:Animals; D001808:Blood Vessels / Q000502:physiology; D002455:Cell Division / Q000187:drug effects; D004068:Digestive System Physiological Phenomena; D004703:Endocrine System / Q000502:physiology*; D006321:Heart / Q000502:physiology; D006801:Humans; D007107:Immune System / Q000502:physiology*; D008969:Molecular Sequence Data; D009496:Neurotensin / Q000097:blood / Q000494:pharmacology / Q000502:physiology*; D014407:Tumor Cells, Cultured
D009496:Neurotensin