[Diabetes following kidney transplantation. Report of 35 cases].
Post-transplant diabetes mellitus (PTDM) is a frequent complication of renal transplantation. It has a prevalence rate ranging from 3 to 46%. We undertook a retrospective study of 175 nondiabetic renal transplant recipients to determine the prevalence rate, clinical characteristics, and risk factors of PTDM in kidney transplant recipients in our region. Thirty five patients (20%) developed PTDM, 50% were diagnosed by 3 months post transplantation. Eight patients (22.8%) were insulin recurrent. PTDM was independent of kidney source, family history of diabetes, age, sex, incidence of acute rejection, body weight gain, steroid or cyclosporine dose, use of beta-blockers and cytomegalovirus infection. Acturial 5 years survival was 79.4% in the diabetic compared to 80.5% in the control group. Patient survival was similar in the two groups. We conclude that PTDM is frequent in our patients. No significant risk factors of PTDM were identified in this study.
Kaaroud
Hayet
H
Service de Néphrologie et de Médecine Interne, Hôpital Charles Nicolle Tunis.
Khiari
Karima
K
Beji
Soumaya
S
Cherif
Lotfi
L
Ben Abdallah
Nejib
N
Ben Moussa
Fatma
F
Ayed
Khaled
K
Ben Abdallah
Taieb
T
Ben Maïz
Hedi
H
D000328:Adult; D003920:Diabetes Mellitus / Q000209:etiology*; D005260:Female; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D015995:Prevalence; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis