title: Optical coherence tomographic findings of dissociated optic nerve fiber layer appearance.
abstract: OBJECTIVE
  To examine the features of optical coherence tomographic (OCT) findings of dissociated optic nerve fiber layer (DONFL) appearance.
  
  
  METHODS
  Case-control study.
  
  
  METHODS
  Twenty-four eyes undergoing vitrectomy for idiopathic epiretinal membrane or macular hole were examined postoperatively using OCT.
  
  
  RESULTS
  Thirteen of the 24 eyes exhibited the DONFL appearance. In these 13 eyes, the OCT images indicated dimples in the retinal nerve fiber layer (RNFL) corresponding to each stria. The RNFL thickness (mean +/- SD) at the dimple site was 38.1 +/- 9.3 microm. The depth of each dimple was 28.6 +/- 8.0 microm. The depths of all the dimples were limited to the RNFL thickness. In the other 11 eyes without the DONFL appearance, OCT images showed no distinct dimples.
  
  
  CONCLUSIONS
  The DONFL appearance is caused by dimples the depths of which are limited to the RNFL thickness.
authors.affiliation: Department of Ophthalmology, School of Medicine, Sapporo Medical University, Sapporo, Japan. ymita@sapmed.ac.jp
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Mitamura
authors.forename: Tomoko
authors.initials: T
authors.lastname: Suzuki
authors.forename: Takamasa
authors.initials: T
authors.lastname: Kinoshita
authors.forename: Nagako
authors.initials: N
authors.lastname: Miyano
authors.forename: Asako
authors.initials: A
authors.lastname: Tashimo
authors.forename: Kenji
authors.initials: K
authors.lastname: Ohtsuka
mesh_terms: D016022:Case-Control Studies; D003941:Diagnostic Techniques, Ophthalmological; D019773:Epiretinal Membrane / Q000601:surgery; D006801:Humans; D009412:Nerve Fibers / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D012165:Retinal Ganglion Cells / Q000473:pathology; D012167:Retinal Perforations / Q000601:surgery; D041623:Tomography, Optical Coherence / Q000379:methods*; D014821:Vitrectomy