[Establishment of canine models of acute mesenteric ischamia].
OBJECTIVE
To establish a new canine model of acute mesenteric ischemia for imaging studies.


METHODS
Ten Beagle dogs were divided into ischemic group (n=8) and control group (n=2). Via a 4F Cobra catheter, the absolute ethanol was selectively injected into the superior mesenteric artery (SMA) for embolization in the former group while the saline was injected in the latter. Imaging study and pathological examination were performed.


RESULTS
Digital subtraction angiography (DSA) revealed that occlusion of some branches of the SMA was induced in the ischemic group while no changes occurred in the control group. The signs of acute mesenteric ischemia were confirmed by CT and pathological examination in the ischemic group whereas no abnormalities identified in the group.


CONCLUSIONS
Canine models of acute mesenteric ischemia can be established by selective catheterization with absolute ethanol injection.
Yang
Bo
B
Department of Radiology, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China. shybomb@163.com
Quan
Xian-yue
XY
Yu
Zhi-jian
ZJ
Yang
Jin-cheng
JC
Long
Qiu-jie
QJ
D000208:Acute Disease; D015901:Angiography, Digital Subtraction; D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D007511:Ischemia / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D008297:Male; D008643:Mesentery / Q000098:blood supply*