title: Inhibitors of squalene biosynthesis and metabolism.
authors.affiliation: Department of Chemistry, University at Stony Brook, New York 11794-3400, USA.
authors.forename: I
authors.initials: I
authors.lastname: Abe
authors.forename: J C
authors.initials: JC
authors.lastname: Tomesch
authors.forename: S
authors.initials: S
authors.lastname: Wattanasin
authors.forename: G D
authors.initials: GD
authors.lastname: Prestwich
mesh_terms: D001685:Biological Factors / Q000737:chemistry / Q000494:pharmacology; D002384:Catalysis; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D013186:Farnesyl-Diphosphate Farnesyltransferase / Q000037:antagonists & inhibitors*; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology; D008190:Lyases / Q000037:antagonists & inhibitors; D015394:Molecular Structure; D010105:Oxygenases / Q000037:antagonists & inhibitors; D013185:Squalene / Q000378:metabolism*; D050603:Squalene Monooxygenase
chemical_list: D001685:Biological Factors; D004791:Enzyme Inhibitors; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D013185:Squalene; D010105:Oxygenases; D050603:Squalene Monooxygenase; D013186:Farnesyl-Diphosphate Farnesyltransferase; D008190:Lyases; C022651:squalene cyclase