title: The effect of extracorporeal shock waves on a rat model of injury to tendo Achillis. A histological and biomechanical study.
abstract: The effects of extracorporeal shock waves (ESWT) on tendon healing were assessed by observing histological and biomechanical parameters in a rat model of injury to the tendo Achillis. The injury was created by inserting an 18-G needle through tendo Achillis in 48 adult Wistar albino rats. The animals were divided into three groups. The first group received radiation only after the operation. The second received no shock waves and the third had 500 15 KV shocks on the second post-operative day. All the rats were killed on the 21st day after surgery. Histopathological analysis showed an increase in the number of capillaries and less formation of adhesions in the study group compared with the control group (p = 0.03). A significantly greater force was required to rupture the tendon in the study group (p = 0.028). Our findings suggest a basis for clinical trials using ESWT.
authors.affiliation: Department of Orthopaedics, Abant Izzet Baysal University Duzce Medical School, Duzce, Turkey.
authors.forename: Z
authors.initials: Z
authors.lastname: Orhan
authors.forename: K
authors.initials: K
authors.lastname: Ozturan
authors.forename: A
authors.initials: A
authors.lastname: Guven
authors.forename: K
authors.initials: K
authors.lastname: Cam
mesh_terms: D000125:Achilles Tendon / Q000293:injuries* / Q000473:pathology / Q000528:radiation effects; D000818:Animals; D001696:Biomechanical Phenomena; D004195:Disease Models, Animal; D019220:High-Energy Shock Waves / Q000627:therapeutic use*; D008297:Male; D011182:Postoperative Care / Q000379:methods; D011183:Postoperative Complications / Q000517:prevention & control; D051381:Rats; D017208:Rats, Wistar; D000267:Tissue Adhesions / Q000517:prevention & control; D014945:Wound Healing / Q000528:radiation effects