title: Analysis of strychnine from detoxified Strychnos nux-vomica [corrected] seeds using liquid chromatography-electrospray mass spectrometry.
abstract: The content of strychnine from Strychnos nux-vomica [corrected] seeds was analyzed and compared to processed seeds by the HPLC-ESI/MS method. Using this technique, levels as low as 1 ng of strychnine were detected. In contrast to conventional UV detectors, this method also made it possible to discriminate brucine. This study resulted in finding the content of strychnine in detoxified seeds to be one tenth of unprocessed Strychnos nux-vomica [corrected] seeds.
authors.affiliation: College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, Republic of Korea.
authors.forename: Young Hae
authors.initials: YH
authors.lastname: Choi
authors.forename: You-Min
authors.initials: YM
authors.lastname: Sohn
authors.forename: Chul Young
authors.initials: CY
authors.lastname: Kim
authors.forename: Kwan Yul
authors.initials: KY
authors.lastname: Oh
authors.forename: Jinwoong
authors.initials: J
authors.lastname: Kim
mesh_terms: D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D012639:Seeds; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D013331:Strychnine / Q000737:chemistry / Q000302:isolation & purification*; D031461:Strychnos nux-vomica
chemical_list: D010936:Plant Extracts; D013331:Strychnine