2'-(4-Fluorophenyl)-[1,2,3]triazolo[4',5':16,17]androst-5-en-3beta-ol methanol hemisolvate.
The asymmetric unit of the title compound, C(25)H(30)FN(3)O.0.5CH(3)OH, contains four symmetry-independent steroid and two methanol molecules. The conformations of the independent steroid molecules are very similar. Intermolecular O-H.O hydrogen bonds create two independent chains, each of which links two of the independent steroid molecules plus one methanol molecule via a co-operative O-H.O-H.O-H pattern. Intermolecular C-H.O and C-H.F interactions are also observed.
Thamotharan
S
S
Department of Physics, Bharathidasan University, Tiruchirappalli 620 024, India.
Parthasarathi
V
V
Gupta
Ranju
R
Jindal
D P
DP
Linden
Anthony
A
D000737:Androstenols / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D008958:Models, Molecular; D008968:Molecular Conformation; D014230:Triazoles / Q000737:chemistry*
C500289:2'-(4-Fluorophenyl)-(1,2,3)triazolo(4',5':16,17)androst-5-en-3beta-ol methanol; D000737:Androstenols; D014230:Triazoles