title: Umbilical endometriosis in pregnancy: a case report.
abstract: To our knowledge, this is the first case reported in the literature of umbilical endometriosis in a pregnant woman. We report a case of umbilical endometriosis in a pregnant woman at 16 weeks of gestation. The patient revealed a reddish-brown polypoid nodule within the umbilical depression, with the typical history of monthly bleeding from the umbilicus. A nodule biopsy, testing of serum levels of CA-125 and a transabdominal ultrasound examination were performed. The diagnosis of endometriosis was confirmed by pathological examination. Serum levels of CA-125 were slightly increased and the pelvic ultrasound examination did not identify ovarian cysts of a possible endometriotic nature. The patient was also examined at 24 weeks' gestation, after delivery and in the late postpartum period. No therapy was given and the lesion resolved spontaneously 2 months after the biopsy was taken.
authors.affiliation: Department of Pediatrics, Obstetrics and Reproductive Medicine, Chair of Obstetrics and Gynecology, University of Siena, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Razzi
authors.forename: P
authors.initials: P
authors.lastname: Rubegni
authors.forename: A
authors.initials: A
authors.lastname: Sartini
authors.forename: S
authors.initials: S
authors.lastname: De Simone
authors.forename: A
authors.initials: A
authors.lastname: Fava
authors.forename: L
authors.initials: L
authors.lastname: Cobellis
authors.forename: M
authors.initials: M
authors.lastname: Fimiani
authors.forename: F
authors.initials: F
authors.lastname: Petraglia
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D004715:Endometriosis / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D010298:Parity; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000473:pathology; D011262:Pregnancy Trimester, Second; D012871:Skin Diseases / Q000175:diagnosis* / Q000473:pathology; D014472:Umbilicus