[Immunohistochemical investigation of estrogen and progesterone receptors in breast tumors].
Estrogen (ER) and progesterone (PR) receptor levels were assayed in 344 breast tumors. The following 4 patterns were identified: ER+ PR(+)--61%; ER+ PR- 24%; ER- PR(+)--15% and ER- PR(-)--35%. While no correlation was found between histological pattern, on the one hand, and the ER/PR ratio and age, on the other, there was one between estrogen and progesterone receptor content, on the one hand, and age, tumor size and metastatic spread to regional lymph nodes, on the other (p > 0.001).
Ellinidi
V N
VN
All-Russia Center of Emergency and Radiation Medicine, Ministry of Emergency Situations of Russia, St. Petersburg.
Anikseeva
N V
NV
Goncharova
O A
OA
Krasnozhon
D A
DA
Fedorov
K A
KA
D000328:Adult; D000367:Age Factors; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis*; D001943:Breast Neoplasms / Q000737:chemistry* / Q000473:pathology*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D011237:Predictive Value of Tests; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*
D014408:Biomarkers, Tumor; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone