title: [Nuchal translucency measurement--non invasive ultrasound screening for fetal abnormalities. Part I].
abstract: OBJECTIVE
  Fetal abnormalities are the most common cause of perinatal and postnatal death and infant handicap. In the last years came into being many diagnostic methods making possible--precise and accurate diagnosis of fetal malformation.
  
  
  METHODS
  Estimation the value of the screening test for fetal abnormalities based on the nuchal translucency measurement between 10-14th week of pregnancy.
  
  
  METHODS
  A group of 675 women with singleton pregnancies undergoing first trimester nuchal translucency measurement. Nuchal translucency thickness was measured by transvaginal ultrasound examination according to Nicolaides. Derived risks were then calculated.
  
  
  RESULTS
  When we used a risk of 1:250 as the cutoff to define a positive result on the screening test, the rate of detection of fetal abnormalities was 100%, with a false positive rate of 1.3%.
  
  
  CONCLUSIONS
  First trimester nuchal translucency measurement is an effective method of screening for fetal abnormalities (obstetrical high-risk group).
authors.affiliation: Instytut Ginekologii i Połoznictwa UM w łodzi.
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Baś-Budecka
authors.forename: Jacek
authors.initials: J
authors.lastname: Suzin
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Lipecka-Kidawska
authors.forename: Piotr
authors.initials: P
authors.lastname: Sieroszewski
mesh_terms: D000328:Adult; D025063:Chromosome Disorders / Q000000981:diagnostic imaging; D000013:Congenital Abnormalities / Q000000981:diagnostic imaging* / Q000196:embryology / Q000517:prevention & control; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D009333:Neck / Q000000981:diagnostic imaging / Q000196:embryology; D011237:Predictive Value of Tests; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D018566:Pregnancy, High-Risk; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal / Q000379:methods