[A case of eosinophilic gastroenteritis: observation of serum IL-5 and sIL-2R levels before and after remission].
56 years-old man was admitted to our hospital because of severe diarrhea and hypereosinophilia. There was tenderness in the middle part of his abdomen. Laboratory examination revealed elevation of serum IL-5 and serum IL-2R value. No pathogens were detected from his stool specimen. An abdominal CT showed neither ascites nor thickening of intestinal wall. Pathological finding showed marked eosinophil infiltration in gastric and colonic mucosa. Eosinophilic gastroenteritis was diagnosed. His symptom was gradually improved spontaneously at the point of diagnosis. But administration of suplatast tosilate was stared because patients with this disease often relapse. Abdominal symptom was completely disappeared and value of serum IL-5 and sIL-2R was decreased at the end of September. This finding may imply pathogenesis of this disease.
To
Masako
M
Department of Allergy and Respiratory Medicine, Doai Memorial Hospital.
Suzuki
Naohito
N
Fueta
Maho
M
Yamada
Hirokazu
H
Ogawa
Cyuhei
C
Sano
Yasuyuki
Y
D004802:Eosinophilia / Q000097:blood* / Q000473:pathology; D005759:Gastroenteritis / Q000097:blood* / Q000473:pathology; D006801:Humans; D015848:Interleukin-5 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D015375:Receptors, Interleukin-2 / Q000097:blood*
D015848:Interleukin-5; D015375:Receptors, Interleukin-2