title: Sperm tail agenesis in a case of consanguinity.
abstract: OBJECTIVE
  To report a case of 100% teratozoospermia in a patient whose family history presented a high degree of consanguinity.
  
  
  METHODS
  Case report.
  
  
  METHODS
  University-based andrology clinic.
  
  
  METHODS
  A 27-year-old man undergoing infertility evaluation.
  
  
  METHODS
  None.
  
  
  METHODS
  Serum hormone analysis, standard (World Health Organization) semen quality evaluation, sperm ultrastructure, lymphocytic karyotype, and polymerase chain reaction screening for Y chromosome microdeletions in peripheral blood.
  
  
  RESULTS
  One hundred percent teratozoospermia characterized by shape alterations of the heads and tail agenesis on standard morphology evaluation, which was confirmed using electron microscopy.
  
  
  CONCLUSIONS
  A case of familial infertility in a consanguineous patient characterized by morphological abnormalities of spermatozoa such as tail agenesis, chromatin subcondensation, and residual cytoplasmic droplets.
authors.affiliation: Department of Medical Pysiopathology, University of Rome "La Sapienza.",Rome, Italy. maurizio.latini@uniroma1.it
authors.forename: Maurizio
authors.initials: M
authors.lastname: Latini
authors.forename: Loredana
authors.initials: L
authors.lastname: Gandini
authors.forename: Andrea
authors.initials: A
authors.lastname: Lenzi
authors.forename: Francesco
authors.initials: F
authors.lastname: Romanelli
mesh_terms: D000328:Adult; D003241:Consanguinity; D006801:Humans; D007248:Infertility, Male / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008854:Microscopy, Electron; D013076:Sperm Count; D013081:Sperm Motility; D013082:Sperm Tail / Q000648:ultrastructure*; D013094:Spermatozoa / Q000002:abnormalities*