Electronic detection of the enzymatic degradation of starch.
[reaction: see text] The enzymatic degradation of starch can be monitored electronically using single-walled carbon nanotubes (SWNTs) as semiconducting probes in field-effect transistors (FETs). Incubation of these devices in aqueous buffer solutions of amyloglucosidase (AMG) results in the removal of the starch from both the silicon surfaces and the side walls of the SWNTs in the FETs, as evidenced by direct imaging and electronic measurements.
Star
Alexander
A
Nanomix, Inc., 5980 Horton Street, Suite 600, Emeryville, California 94608, USA. astar@nano.com
Joshi
Vikram
V
Han
Tzong-Ru
TR
Altoé
M Virginia P
MV
Grüner
George
G
Stoddart
J Fraser
JF
D000687:Amylopectin / Q000737:chemistry; D000688:Amylose / Q000737:chemistry; D002240:Carbohydrate Sequence; D005087:Glucan 1,4-alpha-Glucosidase / Q000737:chemistry / Q000378:metabolism*; D018625:Microscopy, Atomic Force; D008969:Molecular Sequence Data; D037742:Nanotubes, Carbon; D013213:Starch / Q000737:chemistry / Q000378:metabolism*; D014173:Transistors, Electronic
D037742:Nanotubes, Carbon; D013213:Starch; D000688:Amylose; D000687:Amylopectin; D005087:Glucan 1,4-alpha-Glucosidase