title: Watershed segmentation for breast tumor in 2-D sonography.
abstract: Automatic contouring for breast tumors using medical ultrasound (US) imaging may assist physicians without relevant experience, in making correct diagnoses. This study integrates the advantages of neural network (NN) classification and morphological watershed segmentation to extract precise contours of breast tumors from US images. Textural analysis is employed to yield inputs to the NN to classify ultrasonic images. Autocovariance coefficients specify texture features to classify breasts imaged by US using a self-organizing map (SOM). After the texture features in sonography have been classified, an adaptive preprocessing procedure is selected by SOM output. Finally, watershed transformation automatically determines the contours of the tumor. In this study, the proposed method was trained and tested using images from 60 patients. The results of computer simulations reveal that the proposed method always identified similar contours and regions-of-interest (ROIs) to those obtained by manual contouring (by an experienced physician) of the breast tumor in ultrasonic images. As US imaging becomes more widespread, a functional automatic contouring method is essential and its clinical application is becoming urgent. Such a method provides robust and fast automatic contouring of US images. This study is not to emphasize that the automatic contouring technique is superior to the one undertaken manually. Both automatic and manual contours did not, after all, necessarily result in the same factual pathologic border. In computer-aided diagnosis (CAD) applications, automatic segmentation can save much of the time required to sketch a precise contour, with very high stability.
authors.affiliation: Department of Computer Science and Information Engineering, Tunghai University, Taichung, Taiwan. ylhuang@mail.thu.edu.tw
authors.forename: Yu-Len
authors.initials: YL
authors.lastname: Huang
authors.forename: Dar-Ren
authors.initials: DR
authors.lastname: Chen
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D003198:Computer Simulation; D003936:Diagnosis, Computer-Assisted / Q000379:methods; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000379:methods; D016571:Neural Networks, Computer; D016217:Ultrasonography, Mammary / Q000379:methods