Comparison of monophasic vs biphasic administration of contrast material in non-invasive coronary angiography using a 16-row multislice Computed Tomography.
OBJECTIVE
To compare two different techniques for the administration of the bolus of contrast material (cm) in coronary angiography with multislice CT (MSCT) scanner.


METHODS
Thirty consecutive patients were divided into two groups. In group 1 contrast material was administered with the monophasic protocol (140 ml of cm at 4 ml/s). In group 2 contrast material was administered with the biphasic protocol (70 ml of cm at 4 ml/s and 70 ml at 3 ml/s). The angiographic scan was performed in both groups with a 16-row MSCT scanner. Three regions of interest were drawn in each scan throughout the data-set in order to measure attenuation: 1) ascending aorta (ROI1); 2) descending aorta (ROI2); 3) pulmonary artery (ROI3). Attenuation was also assessed at the origin of the main coronary arteries.


RESULTS
No significant differences of the attenuation values were observed at the origin of the coronary arteries (p>0.05). The attenuation profile of the monophasic protocol showed higher and longer attenuation values than the biphasic protocol. CONCLUSIONS. The biphasic administration of contrast material does not supply significant advantages on the enhancement of the great vessels and the coronary arteries in 16-row MSCT coronary angiography.
Cademartiri
Filippo
F
Dipartimento di Radiologia, Erasmus Medical Center, Rotterdam, The Netherlands. filippocademartiri@hotmail.com
Luccichenti
Giacomo
G
Marano
Riccardo
R
Gualerzi
Massimo
M
Brambilla
Lorenzo
L
Coruzzi
Paolo
P
D002985:Clinical Protocols; D003287:Contrast Media / Q000008:administration & dosage*; D017023:Coronary Angiography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods
D003287:Contrast Media