title: Identification of a novel HLA-B*55 variant (B*5513) from a Korean family.
abstract: The novel allele, B*5513, was identified from three siblings of a Korean family. Direct DNA sequencing analysis revealed that B*5513 differed from B*5502 by a single-nucleotide substitution at codon 116 (TTA-->TTC) resulting in an amino acid change from leucine to phenylalanine. This substitution altered serologic reactivity of the B55 molecule to B22-specific alloantisera.
authors.affiliation: Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, South Korea.
authors.forename: H-S
authors.initials: HS
authors.lastname: Park
authors.forename: J-H
authors.initials: JH
authors.lastname: Choi
authors.forename: K W
authors.initials: KW
authors.lastname: Lee
mesh_terms: D019943:Amino Acid Substitution; D001483:Base Sequence; D004247:DNA / Q000235:genetics; D005091:Exons; D014644:Genetic Variation; D015235:HLA-B Antigens / Q000235:genetics*; D006801:Humans; D007723:Korea; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D020641:Polymorphism, Single Nucleotide
chemical_list: D015235:HLA-B Antigens; D004247:DNA