The effect of oscillating low intensity magnetic field on the Na+, K+, Ca++, and Mg++ concentrations in the maternal and fetal circulation of the dually perfused human placental cotyledon.
Dual-sided perfusions of the human placental cotyledon in vitro were used to study effects of low intensity magnetic fields (MFs) of 2 mT, 50 Hz (E1, 10 perfusions) and 5 mT, 50 Hz (E2, 10 perfusions). In the control group C (10 experiments) no field was used. Perfusions lasted 180 min each. Increased release of calcium ions from the placental cotyledon was found in the fetal circulation during perfusion when the 2 mT, 50 Hz MF was used. No changes in the release of sodium and magnesium ions were observed compared to the control group. The 5 mT, 50 Hz oscillating MF intensified the release of sodium ions from the perfused cotyledon both to the fetal and maternal circulation up to the 150th min of the experiment. Increased release of magnesium ions was observed only to the fetal circulation between 120 and 180 min and of calcium ions to the fetal circulation between 60 and 180 min. No significant differences in K concentrations were found between the control and MF exposed cotyledons under conditions of these experiments.
ŁOpucki
Maciej
M
1st Department of Gynaecology, Medical University of Lublin, Lublin, Poland. mLopucki@wp.pl
Czekierdowski
Artur
A
Rogowska
Wanda
W
Kotarski
Jan
J
D002118:Calcium / Q000493:pharmacokinetics / Q000528:radiation effects*; D002824:Chorionic Villi / Q000378:metabolism / Q000528:radiation effects; D005260:Female; D006801:Humans; D008274:Magnesium / Q000493:pharmacokinetics / Q000528:radiation effects*; D008280:Magnetics; D008431:Maternal-Fetal Exchange / Q000528:radiation effects*; D010477:Perfusion; D010920:Placenta / Q000378:metabolism / Q000528:radiation effects*; D021041:Placental Circulation / Q000528:radiation effects; D011188:Potassium / Q000493:pharmacokinetics / Q000528:radiation effects*; D011247:Pregnancy; D012964:Sodium / Q000493:pharmacokinetics / Q000528:radiation effects*; D013997:Time Factors; D014469:Umbilical Arteries / Q000528:radiation effects; D014471:Umbilical Veins / Q000528:radiation effects
D012964:Sodium; D008274:Magnesium; D011188:Potassium; D002118:Calcium