Reactivation of hepatitis C virus after chemotherapy for colon cancer.
Hepatitis C virus (HCV) infection often goes undiagnosed in asymptomatic carriers, but may become clinically relevant during periods of immunosuppression or severe illness. We report the clinical course of HCV reactivation in a patient receiving chemotherapy for metastatic colon cancer. We also review other reports showing the significance of HCV infection in patients being treated with chemotherapy.
Melisko
M E
ME
Comprehensive Cancer Center, University of California, San Francisco, California 94115, USA. mmelisko@medicine.ucsf.edu
Fox
R
R
Venook
A
A
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D002277:Carcinoma / Q000188:drug therapy* / Q000821:virology*; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000821:virology*; D005472:Fluorouracil / Q000008:administration & dosage; D006526:Hepatitis C / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D016867:Immunocompromised Host; D000077146:Irinotecan; D002955:Leucovorin / Q000008:administration & dosage; D008297:Male; D012008:Recurrence
D000077146:Irinotecan; D002955:Leucovorin; D005472:Fluorouracil; D002166:Camptothecin