title: On trial.
abstract: As researchers uncover basic mechanisms that underlie aging, they hope that lessons learned from mice, worms, flies, and other lab denizens will apply to people. Making that leap requires a new set of scientific approaches, from observational studies to the most rigorous of tests, the double-blind, randomized, placebo-controlled clinical trial. Navigating this unique scientific terrain presents new obstacles for basic-science researchers but can provide the ultimate payoff.
authors.forename: R John
authors.initials: RJ
authors.lastname: Davenport
mesh_terms: D000375:Aging / Q000502:physiology; D000818:Animals; D017322:Clinical Trials, Phase II as Topic / Q000379:methods; D004353:Drug Evaluation, Preclinical; D006801:Humans; D023421:Models, Animal; D016032:Randomized Controlled Trials as Topic / Q000379:methods*; D013552:Swine