title: Prediction of survival in gastric carcinoma related to lymph node grading by the new American Joint Committee on Cancer/Union International Contre le Cancer System or the Japanese system.
abstract: OBJECTIVE
  To compare the classification of gastric cancer adopted by the American Joint Committee on Cancer and the Union International contre le Cancer (AJCC/UICC) (number of nodes involved) with the Japanese classification (sites of nodes involved).
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  Teaching hospital, Turkey.
  
  
  METHODS
  134 consecutive patients whose gastric cancer was treated by D2 resection.
  
  
  METHODS
  Kaplan-Meier survival analysis and Cox's regression model.
  
  
  METHODS
  Accuracy of prognosis.
  
  
  RESULTS
  There were no significant differences in survival rates when pN1 and pN2 categories of the AJCC/UICC classification were subdivided into the n1 and n2 categories of the Japanese classification. However, when those in the n1 and n2 categories of the Japanese classification were subdivided into the pN1, pN2 and pN3 categories of the AJCC/UICC classification, survival differed significantly (p = 0.00001). When both classifications were combined in a multivariate analysis the pN category of the AJCC/UICC classification was found to be the most significant independent prognostic factor (p = 0.0001).
  
  
  CONCLUSIONS
  Classification of lymph node status by number of nodes (AJCC/UICC) rather than anatomical site (Japanese) gives a more accurate prognosis.
authors.affiliation: Department of Surgery, Ankara Oncology Research and Teaching Hospital, Demetevler, Ankara, Turkey. drorhancelen@yahoo.com
authors.forename: Orhan
authors.initials: O
authors.lastname: Celen
authors.forename: Emin
authors.initials: E
authors.lastname: Yildirim
authors.forename: Kaptan
authors.initials: K
authors.lastname: Gülben
authors.forename: Uğur
authors.initials: U
authors.lastname: Berberoğlu
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000145:classification / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009367:Neoplasm Staging; D011379:Prognosis; D016016:Proportional Hazards Models; D013274:Stomach Neoplasms / Q000145:classification / Q000401:mortality / Q000473:pathology*; D015996:Survival Rate; D014481:United States