The longest use of liposomal amphotericin B and 5-fluorocytosine in neonatal renal candidiasis.
Bilateral fungal obstruction of the renal collecting system is rare in infancy. Treatment options include medical or surgical procedures. Reports of successful medical treatment with liposomal amphotericin B have been published but the duration of treatment is controversial. We report a 3-week-old preterm baby with myelomeningocele who had experienced acute renal failure related to bilateral renal fungus balls, which improved with percutaneous nephrostomy and 12 weeks of liposomal amphotericin B intravenously combined with 5-fluorocytosine orally for 9 weeks.
Biyikli
Nese Karaaslan
NK
Department of Pediatric Nephrology, Marmara University School of Medicine, Tophanelioglu cd, no 13-15, 81190 Altunizade, Istanbul, Turkey. nesebiyikli@superonline.com
Tugtepe
Halil
H
Akpinar
Ihsan
I
Alpay
Harika
H
Ozek
Eren
E
D058186:Acute Kidney Injury / Q000188:drug therapy* / Q000382:microbiology*; D000666:Amphotericin B / Q000008:administration & dosage*; D000935:Antifungal Agents / Q000008:administration & dosage*; D002177:Candidiasis / Q000188:drug therapy*; D005260:Female; D005437:Flucytosine / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D007674:Kidney Diseases / Q000188:drug therapy* / Q000382:microbiology*; D008081:Liposomes; D013997:Time Factors
D000935:Antifungal Agents; D008081:Liposomes; D000666:Amphotericin B; D005437:Flucytosine