title: Visual loss despite anticoagulation in radiation-induced optic neuropathy.
abstract: Radiation therapy to the brain may produce necrosis and loss of function months after completion of the treatment. The case is presented of a 62-year-old man who developed radiation-induced optic neuropathy 2 years after treatment for a glioma of the left temporal lobe, despite being on anticoagulation therapy. Although anticoagulation appears to be beneficial in cerebral radiation necrosis, its usefulness in the treatment of radiation-induced optic neuropathy is unclear.
authors.forename: Helen V
authors.initials: HV
authors.lastname: Danesh-Meyer
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Savino
authors.forename: Robert C
authors.initials: RC
authors.lastname: Sergott
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D001766:Blindness / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D001932:Brain Neoplasms / Q000532:radiotherapy*; D005910:Glioma / Q000532:radiotherapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009900:Optic Nerve / Q000187:drug effects / Q000473:pathology / Q000528:radiation effects*; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011832:Radiation Injuries / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects; D014794:Visual Fields
chemical_list: D000925:Anticoagulants