title: Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40.
authors.affiliation: Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan. sugamura@mail.tains.tohoku.ac.jp
authors.forename: Kazuo
authors.initials: K
authors.lastname: Sugamura
authors.forename: Naoto
authors.initials: N
authors.lastname: Ishii
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Weinberg
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000818:Animals; D001327:Autoimmune Diseases / Q000188:drug therapy; D018106:CD28 Antigens / Q000502:physiology; D016503:Drug Delivery Systems; D006801:Humans; D007154:Immune System Diseases / Q000188:drug therapy*; D007249:Inflammation / Q000188:drug therapy; D008213:Lymphocyte Activation; D008562:Membrane Glycoproteins / Q000037:antagonists & inhibitors; D051379:Mice; D009369:Neoplasms / Q000188:drug therapy; D053278:OX40 Ligand; D051381:Rats; D053262:Receptors, OX40; D018124:Receptors, Tumor Necrosis Factor / Q000037:antagonists & inhibitors* / Q000502:physiology; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D048069:Tumor Necrosis Factors
chemical_list: D000276:Adjuvants, Immunologic; D018106:CD28 Antigens; D008562:Membrane Glycoproteins; D053278:OX40 Ligand; D053262:Receptors, OX40; D018124:Receptors, Tumor Necrosis Factor; C505716:TNFRSF4 protein, human; C089251:TNFSF4 protein, human; C505717:Tnfrsf4 protein, mouse; C505718:Tnfrsf4 protein, rat; C504586:Tnfsf4 protein, mouse; C504587:Tnfsf4 protein, rat; D048069:Tumor Necrosis Factors