The organization of the corticonuclear and olivocerebellar climbing fiber projections to the rat cerebellar vermis: the congruence of projection zones and the zebrin pattern.
The zonal organization of the corticonuclear and the olivocerebellar climbing fiber projections to the vermis of the cerebellum of the rat was compared to the pattern of zebrin-positive and zebrin-negative bands in material double-stained for zebrin II and for different anterograde tracers injected in subnuclei of the inferior olive, or retrograde tracers injected in the cerebellar and vestibular target nuclei of the Purkinje cells of the vermis. Projection zones A(1), A(X), X, B, C(X) in the vermis and A(2) (accessory A zone) and C(2) in the hemisphere were defined by their efferent corticonuclear and their afferent climbing fiber connections, and were found to share the same topographical framework with the zebrin pattern.
Voogd
Jan
J
Department of Neuroscience, Erasmus MC, Rotterdam, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands. j.voogd@erasmusmc.nl
Ruigrok
Tom J H
TJ
D000818:Animals; D001370:Axonal Transport / Q000502:physiology; D001931:Brain Mapping / Q000379:methods*; D002525:Cerebellar Cortex / Q000033:anatomy & histology / Q000737:chemistry* / Q000502:physiology; D005634:Fructose-Bisphosphate Aldolase / Q000032:analysis*; D008297:Male; D009419:Nerve Tissue Proteins / Q000032:analysis*; D009434:Neural Pathways / Q000033:anatomy & histology / Q000737:chemistry / Q000502:physiology; D009847:Olivary Nucleus / Q000033:anatomy & histology / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar
D009419:Nerve Tissue Proteins; C092565:zebrin I; C071871:zebrin II; D005634:Fructose-Bisphosphate Aldolase