title: Idiopathic stuttering priapism: recovery of detumescence mechanism with temporal use of antiandrogen.
abstract: We report a case of idiopathic stuttering priapism in a 56-year-old Japanese man. We treated his recurrent priapism in stepwise fashion by withdrawal of the alpha/beta-blocker he used for hypertension, administration of low doses of an antiandrogen and baclofen, and finally by increasing the dose of antiandrogen, which lowered his testosterone to the castration level and was effective in preventing priapism. After 6 months of antiandrogen treatment, his erectile function gradually recovered to the baseline level, and he had no recurrence of priapism during the following 6 months without any medication.
authors.affiliation: Department of Urology, Sapporo Medical University, Chuo-ku, Sapporo, Japan.
authors.forename: Nana
authors.initials: N
authors.lastname: Yamashita
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Hisasue
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Kato
authors.forename: Naoya
authors.initials: N
authors.lastname: Masumori
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takahashi
authors.forename: Naoki
authors.initials: N
authors.lastname: Itoh
authors.forename: Taiji
authors.initials: T
authors.lastname: Tsukamoto
mesh_terms: D001418:Baclofen / Q000008:administration & dosage; D001784:Blood Gas Analysis; D002715:Chlormadinone Acetate / Q000008:administration & dosage* / Q000009:adverse effects; D007172:Erectile Dysfunction / Q000139:chemically induced; D006801:Humans; D007511:Ischemia / Q000150:complications / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D010413:Penis / Q000098:blood supply; D010656:Phenylephrine / Q000008:administration & dosage; D011317:Priapism / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D012074:Remission Induction; D055502:Secondary Prevention; D012965:Sodium Chloride / Q000008:administration & dosage; D013739:Testosterone / Q000097:blood; D007507:Therapeutic Irrigation
chemical_list: D002715:Chlormadinone Acetate; D010656:Phenylephrine; D013739:Testosterone; D012965:Sodium Chloride; D001418:Baclofen