title: [Evidence grading system and its usage in clinical decision-making analysis].
abstract: OBJECTIVE
  To explore feasibility of applying evidence grading system in clinical decision-making analysis.
  
  
  METHODS
  Using grading system as well as a quantitative approach to generate the threshold NNT((T)), and conducting clinical decision-making analysis through one study on Asymptomatic carotid atherosclerosis.
  
  
  RESULTS
  NNT((T)) was 12, comparing with no-intervention in the ACA study that NNT = 6. NNT < NNT((T)) indicated the benefits of intervention outweigh the risks and costs.
  
  
  CONCLUSIONS
  To obtain the rate of adverse event and the specifying approximate cost were vital in the process of applying grading system in clinical decision-making.
authors.affiliation: Department of Clinical Epidemiology and EBM, West China Hospital, Chengdu 610041, China.
authors.forename: De-ying
authors.initials: DY
authors.lastname: Kang
authors.forename: Jia-liang
authors.initials: JL
authors.lastname: Wang
authors.forename: Qi
authors.initials: Q
authors.lastname: Hong
authors.forename: Jia-lin
authors.initials: JL
authors.lastname: Jiang
mesh_terms: D032722:Advance Care Planning; D000465:Algorithms; D002340:Carotid Artery Diseases / Q000191:economics / Q000628:therapy; D003659:Decision Making, Organizational; D019317:Evidence-Based Medicine / Q000379:methods*; D017048:Health Care Costs; D006801:Humans; D008962:Models, Theoretical