title: A new ecdysteroid with unique 9beta-OH and four other ecdysteroids from Silene italica ssp. nemoralis.
abstract: A new natural ecdysteroid, 9beta,20-dihydroxyecdysone (1) and four related compounds 5alpha-20-hydroxyecdysone (2), 5alpha-2-deoxy-integristerone A (3), integristerone A (4) and 22-deoxy-integristerone A (5) were isolated from the herb of Silene italica ssp. nemoralis. Compound 1 is the C-9 epimer of the known 9alpha,20-dihydroxyecdysone (6) and represents a peculiar steroid skeleton. The structures of the compounds were elucidated by 1D and 2D NMR, IR and MS spectroscopy.
authors.affiliation: Institute for General and Analytical Chemistry, Budapest University of Technology and Economics, Budapest, Szt. Gellért tér 4, H-1111 Hungary.
authors.forename: András
authors.initials: A
authors.lastname: Simon
authors.forename: Zita
authors.initials: Z
authors.lastname: Pongrácz
authors.forename: Gábor
authors.initials: G
authors.lastname: Tóth
authors.forename: Marianna
authors.initials: M
authors.lastname: Mák
authors.forename: Imre
authors.initials: I
authors.lastname: Máthé
authors.forename: Mária
authors.initials: M
authors.lastname: Báthori
mesh_terms: D026461:Ecdysteroids / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000302:isolation & purification; D008968:Molecular Conformation; D029751:Silene / Q000737:chemistry*
chemical_list: D026461:Ecdysteroids