[Short treatment of donovanosis with azithromycin].
BACKGROUND
Azithromycine is recommended in the treatment of donovanosis with a 7-day treatment cycle. We report the efficacy of a single cure of 1 gram in two patients.


METHODS
Four patients, presenting with donovanosis, were treated with azithromycine according to 2 regimens. The first used 500 mg/d the molecule during 1 week, the second used azithromycine in single cure of 1 gram. The latter led to the complete cure of 2 patients.


CONCLUSIONS
Many antibiotics are used in the treatment of donovanosis. Since 1996, Australian authors have used azithromycine in this indication. A single dose of this molecule appears effective in recent and confined donovanosis.
Clyti
E
E
Service de Dermatologie, Centre Hospitalier Andrée Rosemon, BP 6006, 97306 Cayenne, Guyana. c.emmanuel@voila.fr
Couppié
P
P
Strobel
M
M
Cazanave
C
C
Sainte-Marie
D
D
Pradinaud
R
R
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D017963:Azithromycin / Q000008:administration & dosage*; D006100:Granuloma Inguinale / Q000188:drug therapy*; D006801:Humans; D008297:Male
D000900:Anti-Bacterial Agents; D017963:Azithromycin