[Type B natriuretic peptide. Role in heart failure physiopathology, diagnosis, and prognosis].
Activation of the naturiuretic peptide system is a hallmark of heart failure (HF). In this paper the authors review aspects of the structure, regulation and physiology of the natriuretic peptides. The role of natriuretic peptides in HF progression is discussed. Potential clinical applications of BNP include diagnostic and prognosis in HF and myocardial infarction, as well as therapeutic monitoring of HF patients. Finally we review the therapeutic use of BNP.
Bettencourt
Paulo
P
Serviço de Medicina B, Hospital de São João, Porto, Portugal. pbettfer@esoterica.pt
Azevedo
Ana
A
D006333:Heart Failure / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D020097:Natriuretic Peptide, Brain / Q000502:physiology* / Q000627:therapeutic use; D011379:Prognosis
D020097:Natriuretic Peptide, Brain