[Recurrent pericarditis during meningococcal meningitis. 2 case reports].
BACKGROUND
There is little information on the frequency, physiopathology and management of extra-cerebral manifestations of N. meningitidis meningitis. Articular, pleural and pericardial involvement is occasionally reported with a symptomatology that can be delayed with regard to the initial diagnosis.


METHODS
In two patients in whom the diagnosis of meningococcal meningitis had been confirmed, the progression was towards a recurrent pericarditis up until the 4th month after the initial episode of infection in the first case and pericarditis with tamponade and surgical draining in the second. However, the final outcome was favourable for both patients following treatment with non-steroidal anti-inflammatories (NSAIs).


CONCLUSIONS
The incidence of pericardial involvement is unknown. The distinction has to be made between purulent pericarditis, more frequent in children, and the inflammatory pericarditis that is often of late onset. The indication for surgical draining must be dominated by the clinical hemodynamic impact. The indication for NSAIs and/or acetyl-salicylic acid is not codified (doses, duration), but in the two cases reported here we would privilege NSAIs.
Dupont
M
M
Service des maladies infectieuses, CHU Pontchaillou, Rennes. mathieu.dupont@chu-rennes.fr
du Haut Cilly
F-B
FB
Arvieux
C
C
Tattevin
P
P
Almange
C
C
Michelet
C
C
D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D018450:Disease Progression; D004322:Drainage; D005260:Female; D006801:Humans; D008297:Male; D008585:Meningitis, Meningococcal / Q000150:complications*; D008875:Middle Aged; D010493:Pericarditis / Q000209:etiology* / Q000382:microbiology / Q000473:pathology*; D012008:Recurrence; D016896:Treatment Outcome
D000894:Anti-Inflammatory Agents, Non-Steroidal