title: Antiproliferative effect of indigoid pigments isolated from human urine.
abstract: Two indigoid pigments, red indirubin and blue indigotin, were isolated from the urine of healthy male subjects. The two pigments were assayed on HL60 (human promyelocytic cell line) cells. Preliminary results revealed the antiproliferative effect of the pigments. Indigotin seemed more effective than indirubin.
authors.affiliation: Department of Pharmaceutical Sciences, University of Padova, Via Marzolo 5, I-35131 Padova, Italy. mariateresa.conconi@unipd.it
authors.forename: Maria T
authors.initials: MT
authors.lastname: Conconi
authors.forename: Pier P
authors.initials: PP
authors.lastname: Parnigotto
authors.forename: Carlo V L
authors.initials: CV
authors.lastname: Costa
authors.forename: Graziella
authors.initials: G
authors.lastname: Allegri
mesh_terms: D002455:Cell Division / Q000187:drug effects; D006131:Growth Inhibitors / Q000302:isolation & purification* / Q000494:pharmacology* / Q000652:urine; D018922:HL-60 Cells; D006801:Humans; D066298:In Vitro Techniques; D007203:Indigo Carmine; D007211:Indoles / Q000302:isolation & purification* / Q000494:pharmacology* / Q000652:urine; D008297:Male
chemical_list: D006131:Growth Inhibitors; D007211:Indoles; D007203:Indigo Carmine; C027185:indirubin