Thromboangiitis obliterans: current perspectives and future directions.
Originally described by von Winiwarter in 1879 and by Buerger in 1908, thromboangiitis obliterans became a focus of delayed controversy in the 1960s when its existence as a separate entity came into question. More recently, new information regarding the disease's pathogenesis, as well as a redefinition of its clinical and roentgenographic features, has given further credence to the theory that thromboangiitis obliterans is a distinct clinicopathologic and roentgenographic entity. By critically analyzing both old and new insights, this article assesses the current status and future directions of the disease.
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The Department of Medicine (Cardiovascular Section), Abbott-Northwestern Hospital, Minneapolis, Minnesota, USA.