title: Localization of mast cells in endometrial cysts.
abstract: OBJECTIVE
  Although the presence of mast cells in endometriosis lesions has been reported, there have been no reports of their pathological localization in ovarian endometrial cysts.
  
  
  METHODS
  The localization of mast cells in ovarian endometrial cysts were investigated using hematoxyline and eosin and toluidine blue staining with light microscopy, immunohistochemical c-kits, and electron microscopy.
  
  
  RESULTS
  Mast cells were identified in endometrial cyst tissues. Few mast cells were localized in the endometrial stroma, which is characteristic of endometrial gland-like regions. Many mast cells were noted around blood vessels and the interstitium with fibrosis, that is, the fibrotic interstitium of endometrial cysts.
  
  
  CONCLUSIONS
  Mast cells may be involved in the development and progression of endometriosis. Localization of mast cells suggests a particularly close relationship with fibrosis and adhesion.
authors.affiliation: Department of Gynecology, Omiya Medical Center, Jichi Medical School, Amanuma-cho, Saitama, Japan. fujiwara@jichi.ac.jp
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Fujiwara
authors.forename: Ryo
authors.initials: R
authors.lastname: Konno
authors.forename: Sachiho
authors.initials: S
authors.lastname: Netsu
authors.forename: Masao
authors.initials: M
authors.lastname: Sugamata
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Shibahara
authors.forename: Michitaka
authors.initials: M
authors.lastname: Ohwada
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Suzuki
mesh_terms: D000328:Adult; D004715:Endometriosis / Q000145:classification / Q000473:pathology*; D004717:Endometrium / Q000473:pathology*; D005260:Female; D005355:Fibrosis / Q000473:pathology; D006025:Glycosaminoglycans / Q000737:chemistry; D006493:Heparin / Q000737:chemistry; D006801:Humans; D007150:Immunohistochemistry; D008407:Mast Cells / Q000473:pathology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D010048:Ovarian Cysts / Q000473:pathology*; D010053:Ovary / Q000473:pathology; D010061:Ovulation Detection; D014048:Tolonium Chloride / Q000737:chemistry
chemical_list: D006025:Glycosaminoglycans; D014048:Tolonium Chloride; D006493:Heparin