title: Recurrent parotitis in selective IgA deficiency.
abstract: Recurrent parotitis is an uncommon condition in children. In most cases the etiology is unknown, although the disease is occasionally associated with viral infections, autoimmune disorders and immunodeficiency. We describe, for the first time, a child with recurrent parotitis and isolated immunoglobulin A (IgA) deficiency, without autoimmune disease. As IgA is the main immunoglobulin secreted into the mucosal surfaces, including that of the respiratory and gastrointestinal tracts, and into the saliva, the lack of IgA may be involved in the pathogenesis of recurrent parotitis. We recommend that IgA and other immunoglobulins be tested in all cases of recurrent parotitis.
authors.affiliation: Department of Pediatrics B, Schneider Children's Medical Cneter of Israel, Petah Tiqva, Israel.
authors.forename: Vered
authors.initials: V
authors.lastname: Shkalim
authors.forename: Yehudit
authors.initials: Y
authors.lastname: Monselise
authors.forename: Ronen
authors.initials: R
authors.lastname: Mosseri
authors.forename: Yaron
authors.initials: Y
authors.lastname: Finkelstein
authors.forename: Ben Zion
authors.initials: BZ
authors.lastname: Garty
mesh_terms: D002648:Child; D006801:Humans; D017098:IgA Deficiency / Q000276:immunology*; D007070:Immunoglobulin A / Q000097:blood; D008297:Male; D010309:Parotitis / Q000097:blood / Q000276:immunology* / Q000517:prevention & control; D012008:Recurrence
chemical_list: D007070:Immunoglobulin A