Electron microscopic study of left ventricular cardiomyocyte mitochondriom in rats subjected to head-down tilt.
The mitochondriom of left-ventricular cardiomyocytes in rats subjected to head-down tilt was studied at the electron microscopic level. The ultrastructure of individual mitochondria was disturbed and the number of intermitochondrial contacts in the perinuclear zone increased after 30-day head-down tilt. These parameters did not return to normal over 30 days after 30-day tilt. Repeated 14-day head-down tilt led to a more pronounced increase in the number of intermitochondrial contacts, mitochondria with abnormal ultrastructure were still observed.
Lipina
T V
TV
Department of Cell Biology and Histology, Biological Faculty, M. V. Lomonosov Moscow State University.
Shornikova
M V
MV
Chentsov
Yu S
YS
D000818:Animals; D018475:Head-Down Tilt / Q000009:adverse effects*; D006352:Heart Ventricles / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008928:Mitochondria / Q000648:ultrastructure*; D032383:Myocytes, Cardiac / Q000648:ultrastructure*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D018474:Weightlessness Simulation