Variation in dinucleotide (GT) repeat sequence in the first exon of the STAT6 gene is associated with atopic asthma and differentially regulates the promoter activity in vitro.
Gao
P S
PS
Heller
N M
NM
Walker
W
W
Chen
C H
CH
Moller
M
M
Plunkett
B
B
Roberts
M H
MH
Schleimer
R P
RP
Hopkin
J M
JM
Huang
S K
SK
D000483:Alleles; D001249:Asthma / Q000235:genetics*; D045744:Cell Line, Tumor; D004273:DNA, Neoplasm / Q000235:genetics / Q000378:metabolism; D015226:Dinucleoside Phosphates / Q000235:genetics; D018900:Dinucleotide Repeats / Q000235:genetics* / Q000502:physiology; D005091:Exons / Q000235:genetics*; D014644:Genetic Variation / Q000235:genetics*; D006147:Guanine / Q000378:metabolism* / Q000502:physiology; D006801:Humans; D019169:Jurkat Cells; D009687:Nuclear Proteins / Q000378:metabolism; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics; D011401:Promoter Regions, Genetic / Q000235:genetics* / Q000502:physiology; D050800:STAT6 Transcription Factor; D013941:Thymine / Q000378:metabolism* / Q000502:physiology; D015534:Trans-Activators / Q000235:genetics*; D006113:United Kingdom / Q000453:epidemiology
D004273:DNA, Neoplasm; D015226:Dinucleoside Phosphates; D009687:Nuclear Proteins; D050800:STAT6 Transcription Factor; C494101:STAT6 protein, human; D015534:Trans-Activators; D006147:Guanine; D013941:Thymine