title: [Mathematical algorithm for evaluation of the human cardio-respiratory homeostatic function].
abstract: Mathematical algorithm of the cardiorespiratory homeostasis was determined by oxygen demand (VO2) and carbon dioxide production (VCO2) during maximal physical loading on the bicycle ergometer; calculated and measured parameters of the physical capacity were compared in experiments with long-term (110- to 240-d) isolation of human subjects. Aerobic capacity was evaluated during incremental physical testing in the sitting position on bicycle Elema-Siemens 380-B. The following parameters were measured: peak (maximal loading) heart rate (HRpeak) and VO2, work time, and VO2 at 15 points on the Borg load scale, total aerobic test time and some others. Analysis of the homeostatic function of the cardiorespiratory system with the integral H = (h(u)du failed to state statistically reliable differences (p > 0.05) before and after isolation in group-1; however, it evidenced an increased homeostatic ability (p < 0.05) in group-2 and a decreased homeostatic ability in group-3 after isolation. Hence, the proposed mathematical algorithm showed a good agreement with the aerobic capacity parameters measured using classic methods. There was a high correlation (p < 0.05) between the homeostatic function and aerobic capacity in the groups of subjects and, therefore, determination of the cardiorespiratory homeostatic function can be considered an additional evaluative criterion.
authors.forename: A M
authors.initials: AM
authors.lastname: Nosovskiĭ
authors.forename: V M
authors.initials: VM
authors.lastname: Mikhaĭlov
authors.forename: B B
authors.initials: BB
authors.lastname: Ushakov
mesh_terms: D000465:Algorithms; D005080:Exercise Test; D006339:Heart Rate / Q000502:physiology*; D006706:Homeostasis / Q000502:physiology*; D006801:Humans; D010101:Oxygen Consumption / Q000502:physiology; D012119:Respiration; D018561:Space Simulation