[Visualization of pancreaticobiliary reflux in patients with elevated amylase activity in bile with dynamic secretin-stimulated MR cholangiopancreatography].
Seven patients who had elevated amylase activity in the bile at cholecystectomy and seven normal volunteers were prospectively examined by secretin-stimulated dynamic MRCP. Thirty-five consecutive MR cholangiopancreatograms were acquired at intervals of approximately 10 sec after secretin injection; the acquisition time was 4 sec per image. In all normal volunteers, no apparent signal intensity (SI) changes were noted in the intra- and extrahepatic ducts. Of the 7 patients, the extrahepatic duct showed a sequential SI increase from downstream to upstream in 6; its caliber increased subsequent to pancreatic fluid secretion in 5; and duodenal filling grade tended to be lower in the patients (p < 0.01). These findings were thought to be suggestive of pancreaticobiliary reflux.
Hosoki
Takuya
T
Department of Radiology, Osaka National Hospital.
Hasuike
Yasutoku
Y
Maeda
Noboru
N
Watanabe
Yoshiyuki
Y
Yutani
Kenji
K
Tokuda
Yukiko
Y
Sai
Choi
C
Mitomo
Masanori
M
D000328:Adult; D000368:Aged; D000681:Amylases / Q000378:metabolism*; D001646:Bile / Q000201:enzymology*; D001652:Bile Ducts / Q000473:pathology*; D001655:Bile Reflux / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010183:Pancreatic Ducts / Q000473:pathology*; D012633:Secretin
D012633:Secretin; D000681:Amylases