title: Surgical variables affecting swallowing in patients treated for oral/oropharyngeal cancer.
abstract: BACKGROUND
  Postoperative swallowing function may be influenced by a number of treatment variables; this study examines the relationship of various treatment factors to measures of swallow function.
  
  
  METHODS
  Swallowing was examined with the modified barium swallow procedure in 144 patients surgically treated for oral or oropharyngeal cancer 3 months after healing. Univariate and multivariate correlations were used to examine the relationship between swallowing function and treatment.
  
  
  RESULTS
  Percent tongue base resected and total volume resected were most often correlated with swallowing function in the univariate analyses. Multivariate analyses identified the following combinations with the strongest correlations: (1) percent tongue base resected and closure type for liquids; (2) percent tongue base resected and unreconstructed mandible for pastes; (3) total volume resected, percent lateral floor of mouth resected, and postoperative radiotherapy dose for masticated boluses.
  
  
  CONCLUSIONS
  Total volume resected and percent tongue base resected had a profound impact on postoperative swallowing function. Combinations of percent tongue base resected with other surgical variables had the strongest relationships with overall swallowing function.
authors.affiliation: Communication Sciences and Disorders, Northwestern University, 2240 N. Campus Drive, Evanston, IL 60208-3540, USA. pauloski@merle.it.northwestern.edu
authors.forename: Barbara Roa
authors.initials: BR
authors.lastname: Pauloski
authors.forename: Alfred W
authors.initials: AW
authors.lastname: Rademaker
authors.forename: Jerilyn A
authors.initials: JA
authors.lastname: Logemann
authors.forename: Fred M S
authors.initials: FM
authors.lastname: McConnel
authors.forename: Mary Anne
authors.initials: MA
authors.lastname: Heiser
authors.forename: Salvatore
authors.initials: S
authors.lastname: Cardinale
authors.forename: Cathy L
authors.initials: CL
authors.lastname: Lazarus
authors.forename: Harold
authors.initials: H
authors.lastname: Pelzer
authors.forename: David
authors.initials: D
authors.lastname: Stein
authors.forename: Quinter
authors.initials: Q
authors.lastname: Beery
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003679:Deglutition; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009959:Oropharyngeal Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D011184:Postoperative Period; D020127:Recovery of Function; D012044:Regression Analysis; D016038:Skin Transplantation; D014062:Tongue Neoplasms / Q000532:radiotherapy / Q000601:surgery*