title: Simplified surgical placement and stabilization methods for intracerebroventricular cannulas in rat lateral ventricles.
abstract: Intracerebroventricular cannulation in rat models is an efficient tool for exploring the effects of substances directly injected into the CNS, bypassing the blood-brain barrier. Techniques for surgically securing the ICV cannula require a balance between ease of application and adequate stability. The authors tested several methods of lateral ventricle cannula stabilization, especially focusing on a comparison of cyanoacrylate gel to cranioplastic cement with an anchoring bone screw.
authors.affiliation: Department of Surgery, University of Illinois at Chicago, 60612, USA.
authors.forename: David H
authors.initials: DH
authors.lastname: Jho
authors.forename: Herbert H
authors.initials: HH
authors.lastname: Engelhard
authors.forename: Altair
authors.initials: A
authors.lastname: Juarez
authors.forename: N Joseph
authors.initials: NJ
authors.lastname: Espat
mesh_terms: D000818:Animals; D002404:Catheterization / Q000379:methods / Q000662:veterinary*; D002552:Cerebral Ventricles / Q000601:surgery*; D008297:Male; D051381:Rats; D011916:Rats, Inbred F344; D013514:Surgical Procedures, Operative / Q000662:veterinary*