title: Oxamides as novel NR2B selective NMDA receptor antagonists.
abstract: A novel series of oxamides derived from indole-2-carboxamides was identified as potent NR2B selective NMDA receptor antagonists. Several members of this group showed good analgesic activity in the mouse formalin test.
authors.affiliation: Gedeon Richter Ltd, 10, PO Box 27, H-1475 Budapest, Hungary.
authors.forename: Gizella
authors.initials: G
authors.lastname: Barta-Szalai
authors.forename: István
authors.initials: I
authors.lastname: Borza
authors.forename: Eva
authors.initials: E
authors.lastname: Bozó
authors.forename: Csilla
authors.initials: C
authors.lastname: Kiss
authors.forename: Béla
authors.initials: B
authors.lastname: Agai
authors.forename: Agnes
authors.initials: A
authors.lastname: Proszenyák
authors.forename: György M
authors.initials: GM
authors.lastname: Keseru
authors.forename: Anikó
authors.initials: A
authors.lastname: Gere
authors.forename: Sándor
authors.initials: S
authors.lastname: Kolok
authors.forename: Kornél
authors.initials: K
authors.lastname: Galgóczy
authors.forename: Csilla
authors.initials: C
authors.lastname: Horváth
authors.forename: Sándor
authors.initials: S
authors.lastname: Farkas
authors.forename: György
authors.initials: G
authors.lastname: Domány
mesh_terms: D000818:Animals; D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology*; D051379:Mice; D008958:Models, Molecular; D015394:Molecular Structure; D016202:N-Methylaspartate / Q000494:pharmacology*; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship
chemical_list: D007211:Indoles; D016194:Receptors, N-Methyl-D-Aspartate; D016202:N-Methylaspartate