Simplified surgical placement and stabilization methods for intracerebroventricular cannulas in rat lateral ventricles.
Intracerebroventricular cannulation in rat models is an efficient tool for exploring the effects of substances directly injected into the CNS, bypassing the blood-brain barrier. Techniques for surgically securing the ICV cannula require a balance between ease of application and adequate stability. The authors tested several methods of lateral ventricle cannula stabilization, especially focusing on a comparison of cyanoacrylate gel to cranioplastic cement with an anchoring bone screw.
Jho
David H
DH
Department of Surgery, University of Illinois at Chicago, 60612, USA.
Engelhard
Herbert H
HH
Juarez
Altair
A
Espat
N Joseph
NJ
D000818:Animals; D002404:Catheterization / Q000379:methods / Q000662:veterinary*; D002552:Cerebral Ventricles / Q000601:surgery*; D008297:Male; D051381:Rats; D011916:Rats, Inbred F344; D013514:Surgical Procedures, Operative / Q000662:veterinary*