Effectiveness of gabapentin for treatment of burning mouth syndrome.
Burning mouth syndrome is a debilitating disorder involving oral pain that may have at least 4 underlying causes. Although several treatments have been proposed, none seems to be universally effective. We report the case of a 67-year-old woman with unremitting oral burning that is increased with the application of anesthetic agents. Initial treatments with nortriptyline hydrochloride and sertraline hydrochloride were contraindicated because of adverse effects, but the administration of gabapentin significantly reduced oral burning. The present case illustrates the effectiveness of gabapentin as a treatment of burning mouth syndrome.
White
Theresa L
TL
Clinical Olfactory Research Center, Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY 13210, USA. whitet@mailupstate.edu
Kent
Paul F
PF
Kurtz
Daniel B
DB
Emko
Precha
P
D000085:Acetates / Q000627:therapeutic use*; D000368:Aged; D000588:Amines; D002054:Burning Mouth Syndrome / Q000175:diagnosis / Q000188:drug therapy*; D003509:Cyclohexanecarboxylic Acids; D005260:Female; D018755:GABA Agonists / Q000627:therapeutic use*; D000077206:Gabapentin; D006801:Humans; D005680:gamma-Aminobutyric Acid
D000085:Acetates; D000588:Amines; D003509:Cyclohexanecarboxylic Acids; D018755:GABA Agonists; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin