Isolation of 8-hydroxyglycitein and 6-hydroxydaidzein from soybean miso.
We isolated from soybean miso 8-hydroxyglycitein and 6-hydroxydaidzein as DPPH-radical scavengers, and elucidated their chemical structures by mass spectrometric, and (1)H- and (13)C-NMR spectrosopic analyses. These compounds showed DPPH-radical scavenging activity as high as that of alpha-tocopherol, 8-hydroxygenistein and 8-hydroxydaidzein. This is the first report of the isolation of 8-hydroxyglycitein from a natural source.
Hirota
Akira
A
Laboratory of Applied Microbiology, School of Food and Nutritional Sciences, University of Shizuoka, Shizuoka, Japan. hirotaa@u-shizuoka-ken.ac.jp
Inaba
Miyuki
M
Chen
Yu-Chi
YC
Abe
Naoki
N
Taki
Shoji
S
Yano
Masamichi
M
Kawaii
Satoru
S
D001713:Biphenyl Compounds; D049109:Cell Proliferation / Q000187:drug effects; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018922:HL-60 Cells; D006801:Humans; D006834:Hydrazines; D007529:Isoflavones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D048789:Phytoestrogens / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010851:Picrates; D013025:Glycine max / Q000737:chemistry*
C497191:8-hydroxyglycitein; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D006834:Hydrazines; D007529:Isoflavones; D048789:Phytoestrogens; D010851:Picrates; C004742:daidzein; C086566:glycitein; C004931:1,1-diphenyl-2-picrylhydrazyl; C476812:6-hydroxydaidzein