title: Endovascular treatment of intracerebral mycotic aneurysm before surgical treatment of infective endocarditis.
abstract: Mycotic aneurysms are rarely seen in patients who have infective endocarditis, and the management of these patients remains controversial. We present the case of a patient who had infective endocarditis complicated by a mycotic aneurysm of the left middle cerebral artery. There was substantial mitral regurgitation, and Streptococcus viridans was isolated from the blood samples. Dysarthria appeared during the 4th week of the antibiotic therapy, but resolved completely 8 hours after onset. The left middle cerebral artery was embolized with platinum detachable coils. On the 7th day after the radiologic intervention, the native mitral valve was replaced with a 33-mm St. Jude Medical bi-leaflet mechanical mitral prosthesis. Most mycotic aneurysms show notable regression of symptoms with effective antibiotic treatment, and a very few may diminish in size. However it is impossible to predict the response of these aneurysms to therapy. To prevent the perioperative rupture of mycotic aneurysms and intracranial hemorrhage, priority should be given to endovascular interventions to treat cerebrovascular aneurysms in patients such as ours.
authors.affiliation: Department of Cardiovascular Surgery, Kosuyolu Heart and Research Hospital, 81020 Kadikoy, Istanbul, Turkey. gulayhasan@superonline.com
authors.forename: Hasan Basri
authors.initials: HB
authors.lastname: Erdogan
authors.forename: Vedat
authors.initials: V
authors.lastname: Erentug
authors.forename: Nilgun
authors.initials: N
authors.lastname: Bozbuga
authors.forename: Deniz
authors.initials: D
authors.lastname: Goksedef
authors.forename: Esat
authors.initials: E
authors.lastname: Akinci
authors.forename: Cevat
authors.initials: C
authors.lastname: Yakut
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002536:Cerebral Arteries / Q000473:pathology; D004621:Embolization, Therapeutic / Q000295:instrumentation; D004697:Endocarditis, Bacterial / Q000150:complications / Q000601:surgery*; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000382:microbiology; D012421:Rupture / Q000517:prevention & control; D034363:Viridans Streptococci / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents