title: [Prevalence of atopic dermatitis in schoolchildren from Cartagena (Spain) and relationship with sex and pollution].
abstract: BACKGROUND
  Atopic dermatitis is favored by exogenous factors, such as air pollution interacting with a genetic predisposition.
  
  
  OBJECTIVE
  The aim of the present study was to evaluate the influence of sex and air pollution in the city of Cartagena on the prevalence of atopic dermatitis.
  
  
  METHODS
  We performed a cross-sectional study using the ISAAC questionnaire in schoolchildren aged 13 and 14 years old from Cartagena (Murcia). The influence of sex and the schools' location in two distinct areas (polluted and unpolluted) on the prevalence of atopic dermatitis and its severity (described as being awakened by nocturnal itching) was analyzed.
  
  
  RESULTS
  The prevalence of atopic eczema was 6.3 %. Atopic eczema was severe in 19 % of the cases. Risk factors for atopic eczema were female sex (OR 2.19 95 % CI: 1.59-3. 02) and attending school in a polluted area (OR: 1.83, 95 % CI 1.01-1.87) but these factors were not associated with greater severity.
  
  
  CONCLUSIONS
  Air pollution is associated with a higher prevalence of atopic eczema and there is a trend that this eczema is more severe. The condition was more prevalent among girls.
authors.affiliation: Servicio de Pediatría, Hospital Clínico San Carlos de Madrid, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Martín Fernández-Mayoralas
authors.forename: J M
authors.initials: JM
authors.lastname: Martín Caballero
authors.forename: L
authors.initials: L
authors.lastname: García-Marcos Alvarez
mesh_terms: D000293:Adolescent; D003430:Cross-Sectional Studies; D003876:Dermatitis, Atopic / Q000453:epidemiology*; D004787:Environmental Pollution; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology