Nanosuspensions: a promising drug delivery strategy.
Nanosuspensions have emerged as a promising strategy for the efficient delivery of hydrophobic drugs because of their versatile features and unique advantages. Techniques such as media milling and high-pressure homogenization have been used commercially for producing nanosuspensions. Recently, the engineering of nanosuspensions employing emulsions and microemulsions as templates has been addressed in the literature. The unique features of nanosuspensions have enabled their use in various dosage forms, including specialized delivery systems such as mucoadhesive hydrogels. Rapid strides have been made in the delivery of nanosuspensions by parenteral, peroral, ocular and pulmonary routes. Currently, efforts are being directed to extending their applications in site-specific drug delivery.
Patravale
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VB
Pharmaceutical Division, University Institute of Chemical Technology, Matunga, Mumbai-400 019, India. vbp_muict@yahoo.co.in
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Abhijit A
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Kulkarni
R M
RM
D004333:Drug Administration Routes; D016503:Drug Delivery Systems; D036103:Nanotechnology; D009288:Naproxen / Q000008:administration & dosage / Q000737:chemistry; D010316:Particle Size; D004364:Pharmaceutical Preparations / Q000008:administration & dosage* / Q000737:chemistry; D012995:Solubility; D013535:Suspensions / Q000737:chemistry*; D013678:Technology, Pharmaceutical
D004364:Pharmaceutical Preparations; D013535:Suspensions; D009288:Naproxen