[Hemoglobin S in the Venezuelan population].
Hemoglobin variants were introduced in Venezuela mainly by the descendants of African slaves; their distribution is determined by the flow of these populations into the country. The most prevalent hemoglobin variants are Hb S and Hb C. Hb S has a frequency between 0 and 7% depending on the African component of the region. The study of beta s gene linked haplotypes has been used to investigate the origins of African populations in America. In Venezuela, the beta s mutation is associated with the Benin and Bantu haplotypes (CAR) with a high frequency. According to these results the Africans transported to Venezuela were of Bantu origin as it has been showed by the historical records.
Salazar-Lugo
Raquel
R
Departamento de Bioanálisis, Escuela de Ciencias, Núeleo de Suere, Universidad de Oriente, Cumaná, Venezuela. raquelugove@yahoo.com
D044383:Black People; D006451:Hemoglobin, Sickle / Q000032:analysis*; D006801:Humans; D007199:Indians, South American; D014687:Venezuela
D006451:Hemoglobin, Sickle