A stereodivergent asymmetric approach to difluorinated aldonic acids.
A (bromodifluoromethyl)alkyne has been deployed in a stereoselective route to difluorinated aldonic acid analogues, in which a Sharpless asymmetric dihydroxylation reaction and diastereoisomer separation set the stage for phenyl group oxidation.
Audouard
Christophe
C
Department of Chemistry, University of Leicester, University Road, Leicester, UK LE1 7RH.
Barsukov
Igor
I
Fawcett
John
J
Griffith
Gerry A
GA
Percy
Jonathan M
JM
Pintat
Stéphane
S
Smith
Clive A
CA