Interstrand communication between 2'-N-(pyren-1-yl)methyl-2'-amino-LNA monomers in nucleic acid duplexes: directional control and signalling of full complementarity.
Very efficient interstrand communication systems in nucleic acid duplexes, based on pyrene excimer formation between 2'-N-(pyren-1-yl)methyl-2'-amino-LNA monomers, demonstrate the versatility of functionalized 2'-amino-LNA monomers for Angstrom-scale chemical engineering.
Hrdlicka
Patrick J
PJ
Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, DK-5230 Odense M, Denmark.
Babu
B Ravindra
BR
Sørensen
Mads D
MD
Wengel
Jesper
J
D020137:Base Pair Mismatch; D002616:Chemical Engineering / Q000379:methods; D015342:DNA Probes; D018076:DNA, Complementary / Q000737:chemistry; D006358:Hot Temperature; D015394:Molecular Structure; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D009696:Nucleic Acids / Q000737:chemistry*; D009841:Oligonucleotides; D016376:Oligonucleotides, Antisense / Q000737:chemistry*; D011721:Pyrenes / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
D015342:DNA Probes; D018076:DNA, Complementary; D009696:Nucleic Acids; D009841:Oligonucleotides; D016376:Oligonucleotides, Antisense; D011721:Pyrenes; C477371:locked nucleic acid