title: Structural analysis of 1-aminocyclopropane-1-carboxylate deaminase: observation of an aminyl intermediate and identification of Tyr 294 as the active-site nucleophile.
authors.affiliation: Division of Medicinal Chemistry, College of Pharmacy and Department of Chemistry and Biochemistry, University of Texas, Austin, TX 78712, USA.
authors.forename: Subramanian
authors.initials: S
authors.lastname: Karthikeyan
authors.forename: Zongbao
authors.initials: Z
authors.lastname: Zhao
authors.forename: Chai-Lin
authors.initials: CL
authors.lastname: Kao
authors.forename: Qingxian
authors.initials: Q
authors.lastname: Zhou
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Tao
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
authors.forename: Hung-Wen
authors.initials: HW
authors.lastname: Liu
mesh_terms: D001665:Binding Sites; D019755:Carbon-Carbon Lyases / Q000737:chemistry*; D008958:Models, Molecular; D017354:Point Mutation; D011549:Pseudomonas / Q000201:enzymology; D013237:Stereoisomerism; D014443:Tyrosine / Q000737:chemistry*
chemical_list: D014443:Tyrosine; C033634:1-aminocyclopropane-1-carboxylate deaminase; D019755:Carbon-Carbon Lyases