One step selective 5'-O-allylation of thymidine using microwave or ultrasound activation.
An improved procedures for the synthesis of 5'-O-allylthymidine via one step selective allylation of thymidine using either ultrasound or microwave activation is described.
Roy
Vincent
V
Université de Limoges, Laboratoire de Chimie des Substances Naturelles, Faculté des Sciences et Techniques, 123 Avenue Albert Thomas, F-87060 Limoges, France.
Colombeau
Ludovic
L
Zerrouki
Rachida
R
Krausz
Pierre
P
D002241:Carbohydrates / Q000737:chemistry*; D008872:Microwaves; D008956:Models, Chemical; D011725:Pyridines / Q000737:chemistry; D013010:Sonication; D013696:Temperature; D013936:Thymidine / Q000737:chemistry*; D013997:Time Factors; D014465:Ultrasonics
D002241:Carbohydrates; D011725:Pyridines; C023666:pyridine; D013936:Thymidine