title: [Role of new biological therapy in psoriasis treatment].
abstract: Psoriasis is an inflammatory disease mediated by immune system T cells. The use of current systemic immunosuppressive therapies is limited by an inability to maintain disease remission safely knowledge on. Advances in recombinant DNA technology and the increase in knowledge on psoriasis immunopathology knowledge have led to the development of numerous biologic agents for the treatment of the disease. In this review the mechanisms of action for these new agents, as well as their safety profiles and efficacy data have been analyzed.
authors.affiliation: Servicio de Farmacia, Hospital Universitario 12 de Octubre, Madrid. susancortijo@yahoo.es
authors.forename: S
authors.initials: S
authors.lastname: Cortijo Cascajares
authors.forename: M P
authors.initials: MP
authors.lastname: García Rodríguez
authors.forename: M
authors.initials: M
authors.lastname: Campo Angora
authors.forename: O
authors.initials: O
authors.lastname: Serrano Garrote
authors.forename: A
authors.initials: A
authors.lastname: Herreros de Tejada
mesh_terms: D001691:Biological Therapy; D002986:Clinical Trials as Topic; D003879:Dermatologic Agents / Q000627:therapeutic use*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D011565:Psoriasis / Q000188:drug therapy*
chemical_list: D003879:Dermatologic Agents; D007166:Immunosuppressive Agents