[A case report of extrahepatic hepatocellular carcinoma with lymphocytic infiltration].
Hepatocellular carcinoma (HCC) with lymphocytic infiltration is a rare entity recently described, sometimes associated with hepatitis C. Histologically, remarkable inflammatory cell infiltration of cancer nests is observed, mostly composed of T cytotoxic lymphocytes. When prominent, this inflammatory cell component can obscure the neoplastic cells, leading to diagnostic difficulty. Alike tumors showing dense lymphocytic infiltrate, it discloses a better prognosis than other HCC. We report a case of HCC with lymphocytic infiltration arising in the right suprarenal space, in a 45-year-old man with no chronic liver disease. The patient is alive without recurrence three years after surgical resection. This report is original because HCC growing ectopically are rare and need to be distinguished, specially in the right retroperitoneal, from metastatic adrenal HCC.
Sturm
Nathalie
N
Laboratoire de Pathologie Cellulaire, Centre Hospitalo-Universitaire Albert Michallon, Grenoble.
Chaffanjon
Philippe
P
Salameire
Dimitri
D
Zarski
Jean Pierre
JP
Letoublon
Christian
C
Sengel
Christian
C
Brambilla
Elisabeth
E
D000008:Abdominal Neoplasms / Q000276:immunology / Q000473:pathology* / Q000601:surgery; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000276:immunology / Q000473:pathology* / Q000601:surgery; D002828:Choristoma / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D008214:Lymphocytes / Q000473:pathology*; D008297:Male; D017154:Stromal Cells / Q000473:pathology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome