title: Reference group choice and antibiotic resistance outcomes.
abstract: Two types of cohort studies examining patients infected with methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) were contrasted, using different reference groups. Cases were compared to uninfected patients and patients infected with the corresponding, susceptible organism. VRE and MRSA were associated with adverse outcomes. The effect was greater when uninfected control patients were used.
authors.affiliation: Duke University Medical Center, Durham, North Carolina 27710, USA. kaye0001@mc.duke.edu
authors.forename: Keith S
authors.initials: KS
authors.lastname: Kaye
authors.forename: John J
authors.initials: JJ
authors.lastname: Engemann
authors.forename: Essy
authors.initials: E
authors.lastname: Mozaffari
authors.forename: Yehuda
authors.initials: Y
authors.lastname: Carmeli
mesh_terms: D015331:Cohort Studies; D035061:Control Groups; D016983:Enterococcus; D006760:Hospitalization / Q000191:economics; D006801:Humans; D016106:Methicillin Resistance; D015999:Multivariate Analysis; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000191:economics; D013211:Staphylococcus aureus; D020713:Vancomycin Resistance; D014946:Wound Infection / Q000188:drug therapy* / Q000191:economics