Effect of supplementary feeding of vitamin K1 on difethialone treated Indian gerbil, Tatera indica Hardwicke in laboratory.
Two dosages (1 and 2 mg/kg) of vitamin K1 supplementation for 5 and 15 days were given to Indian gerbil T. indica fed on difethialone bait (0.0025%) for one day. The results indicated that the lower dosage could not reverse the anticoagulation process, however the period of mortality was considerably increased from 3-9 days (in control) to 5-14 days (5 days supplementation regime). Subsequently when the vitamin K1 dosage was doubled and given for 15 days, there was 100% reversal of anticoagulation process and all the test gerbils became normal within a month of poisoning with difethialone bait.
Chaudhary
Vipin
V
All India Coordinated Research Project on Rodent Control, Central Arid Zone Research Institute, Jodhpur 342 003, India.
Tripathi
R S
RS
Poonia
F S
FS
D015110:4-Hydroxycoumarins / Q000506:poisoning*; D000821:Animal Feed; D000818:Animals; D000925:Anticoagulants / Q000494:pharmacology; D019587:Dietary Supplements; D005849:Gerbillinae; D012378:Rodenticides / Q000506:poisoning; D013997:Time Factors; D010837:Vitamin K 1 / Q000494:pharmacology*
D015110:4-Hydroxycoumarins; D000925:Anticoagulants; D012378:Rodenticides; D010837:Vitamin K 1; C060340:difethialone