Catching some Zs: a new protein for spatial regulation of bacterial cytokinesis.
Prior to its duplication, the bacterial nucleoid exerts local negative control over assembly of the cytokinetic Z ring to prevent potential cutting of the chromosome. In this issue of Cell, Wu and Errington show that a specific nucleoid-associated protein mediates this nucleoid occlusion effect, providing the first mechanistic insight into this key spatial regulatory system.
Margolin
William
W
Department of Microbiology and Molecular Genetics, University of Texas Medical School, 6431 Fannin Street, Houston, Texas 77030, USA.
D001412:Bacillus subtilis / Q000166:cytology* / Q000235:genetics / Q000502:physiology*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D002455:Cell Division; D002876:Chromosomes, Bacterial; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D009154:Mutation
D001426:Bacterial Proteins