title: [Coronary risk assessment in subjects with type 2 diabetes mellitus. General population-based scores or specific scores?].
abstract: Coronary risk in patients with type 2 diabetes mellitus can be calculated using population-based scores or diabetes-specific scores. Our objective was to compare the results with both scores in a group of patients with type 2 diabetes and no history of cardiovascular disease. We analyzed the results for 101 patients aged 40 to 65 years with type 2 diabetes and no prior cardiovascular disease. Two scales were used, one based on the general population (Framingham function adapted from the REGICOR study), and the other based on the population with type 2 diabetes mellitus (UKPDS risk engine). The average 10-year likelihood of coronary events was 5.8 (2.5)% and 15.7 (8.4)% for the REGICOR risk score and the UKPDS risk score, respectively (P<.001), with a Pearson correlation coefficient of 0.525 (P<.01). Risk was higher in men (19.2 [8.7]% based on the UKPDS score, and 5.6 [2.8]% based on the REGICOR score, P<.001). The figures for women were 11.3 [5.9]% and 5.9 [2.1]% with the UKPDS and REGICOR scores, respectively (P<.001). Our results suggest that substantially different findings are obtained when general population-based scores or specific scores are used to assess cardiovascular risk in subjects with type 2 diabetes.
authors.affiliation: Servicio de Endocrinología y Diabetes, Hospital Clínic i Universitari, Barcelona, Spain.
authors.forename: Rubén
authors.initials: R
authors.lastname: Hernáez
authors.forename: Lucía
authors.initials: L
authors.lastname: Choque
authors.forename: Margarita
authors.initials: M
authors.lastname: Giménez
authors.forename: Angels
authors.initials: A
authors.lastname: Costa
authors.forename: Juan I
authors.initials: JI
authors.lastname: Márquez
authors.forename: Ignacio
authors.initials: I
authors.lastname: Conget
mesh_terms: D000328:Adult; D000368:Aged; D003327:Coronary Disease / Q000209:etiology* / Q000517:prevention & control; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D016013:Likelihood Functions; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment