title: Continuous infusion of vecuronium in children.
abstract: The average dose of vecuronium required in children continuous infusion to attain a steady state block of 90% was determined. The electromyographic (EMG) response and mechanical response to supramaximal stimulation of the ulnar never recorded simultaneously, were significantly correlated in four children. The steady-state infusion rate requirement of vecuronium was 1.4 +/- 0.03 micro g/kg/min during 2% enflurane anesthesia and 3.1 +/- 0.03 micro g/kg/min during 1% halothane anesthesia. The spontaneous recovery time to 25% of the control by EMG during halothane and enflurane anesthesia was 12.6 +/- 1.1 and 10.3 +/- 1.5 min, respectively, after termination of the infusion. There was no cumulative effect after prolonged vecuronium infusion.
authors.affiliation: Department of Anesthesiology, Kobe University School of Medicine, Kobe, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Obara
authors.forename: H
authors.initials: H
authors.lastname: Hoshina
authors.forename: O
authors.initials: O
authors.lastname: Tanaka
authors.forename: R
authors.initials: R
authors.lastname: Chuma
authors.forename: H
authors.initials: H
authors.lastname: Kaetsu
authors.forename: N
authors.initials: N
authors.lastname: Maekawa
authors.forename: S
authors.initials: S
authors.lastname: Iwai