title: In vitro activities of iodonium salts against oral and dental anaerobes.
abstract: The comparative in vitro activities of 11 iodonium salt compounds, 0.12% chlorhexidine, and four antimicrobial agents against 322 anaerobic and fastidious potential dental and periodontal bacterial pathogens were studied. Iodonium salts 3, 4, 5, 9, and 10 had in vitro activities comparable to that of chlorhexidine against most isolates. These compounds may be suitable for incorporation into an oral mouthwash.
authors.affiliation: R. M. Alden Research Laboratory, 2021 Santa Monica Blvd., Suite 740 E, Santa Monica, CA 90404, USA. ejcgmd@aol.com
authors.forename: Ellie J C
authors.initials: EJ
authors.lastname: Goldstein
authors.forename: Diane M
authors.initials: DM
authors.lastname: Citron
authors.forename: Yumi
authors.initials: Y
authors.lastname: Warren
authors.forename: C Vreni
authors.initials: CV
authors.lastname: Merriam
authors.forename: Kerin
authors.initials: K
authors.lastname: Tyrrell
authors.forename: Helen
authors.initials: H
authors.lastname: Fernandez
authors.forename: Ukkiramapandian
authors.initials: U
authors.lastname: Radhakrishnan
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Stang
authors.forename: Georg
authors.initials: G
authors.lastname: Conrads
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D002710:Chlorhexidine / Q000494:pharmacology; D004202:Disinfectants / Q000494:pharmacology; D006801:Humans; D009055:Mouth / Q000382:microbiology*; D009067:Mouthwashes / Q000494:pharmacology; D009861:Onium Compounds / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D014070:Tooth / Q000382:microbiology*
chemical_list: D000890:Anti-Infective Agents; D004202:Disinfectants; D009067:Mouthwashes; D009861:Onium Compounds; D002710:Chlorhexidine