[Advanced gastric cancer successfully treated by TS-1--case report].
A 73-year-old woman came to our hospital because of poor appetite, and careful examination revealed a Borrmann type 2 tumor on the posterior wall of the lower body of the stomach as well as enlarged para aortic-lymph nodes. Surgery was performed in November 2000, but because the para-aortic lymph nodes were densely adherent to the aorta, it was impossible to dissect the lymph nodes from the wall (N3, Stage IV). Postoperatively, a course of TS-1 100 mg/day for 4 weeks and discontinuation for 2 weeks was started. After one course of TS-1, the enlarged para-aortic lymph nodes were no longer seen on abdominal computed tomography (CT). The dose of TS-1 was subsequently reduced to 80 mg/day because of adverse effects. Although the patient is still taking TS-1, she is well with no signs of recurrence 34 months after surgery.
Michigami
Shinya
S
Dept. of Surgery, Imazato Gastro-Enteric Hospital.
Yada
Katsushi
K
Morita
Masahiro
M
Hibuse
Yoshizumi
Y
Ogawa
Yoshinari
Y
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001012:Aorta, Abdominal / Q000473:pathology; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008207:Lymphatic Metastasis; D010094:Oxonic Acid / Q000627:therapeutic use*; D011725:Pyridines / Q000627:therapeutic use*; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000627:therapeutic use*
D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid