title: [Acute myocardial infarct as a result of external compression caused by an expanding pulmonary adenocarcinoma].
abstract: The case report describes a rare cause of acute myocardial infarction. 68-years old man with the cancer triplicity (follicular and papillar carcinoma of the thyroid gland, Grawitz tumor, bronchogenic carcinoma with generalization) was admitted to the intensive care unit for the sudden onset of chest pain, positivity of cardioselective enzymes and signs of cardiogenic shock. Echocardiographic examination proved diaphragmatic akinesis with low left ventricular ejection fraction about 30%. The acute coronary angiogram revealed unimportant atherosclerotic narrowing of the left coronary artery and a long significant stenosis in the proximal portion of the right coronary artery untypical for atherosclerotic lesion suspicious of extramural compression. A pathological vascularization to the extramyocardial region was documented during right coronary angiogram. The patient was treated conservatively and finally transferred to the pulmonary disease department, where he died of progression of the cancer disease two months later. Postmortem examination found spreading of the bronchogenic adenocarcinoma to the pericardium along the course of the right coronary artery, but neither direct infiltration of the vessel wall by the tumor nor atherosclerotic disease of the proximal portion of the right coronary artery were proved. These findings together with the coronary angiogram demonstrate a rare cause of the myocardial infarction due to the extramural compression by the malignant tumor.
authors.affiliation: I. interní klinika Lékarské fakulty UP a FN, Olomouc.
authors.forename: A
authors.initials: A
authors.lastname: Bulava
authors.forename: M
authors.initials: M
authors.lastname: Skvarilová
authors.forename: D
authors.initials: D
authors.lastname: Marek
authors.forename: E
authors.initials: E
authors.lastname: Kociánová
authors.forename: J
authors.initials: J
authors.lastname: Lukl
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology; D000368:Aged; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis / Q000209:etiology*; D009206:Myocardium / Q000473:pathology; D009361:Neoplasm Invasiveness; D009378:Neoplasms, Multiple Primary; D010496:Pericardium / Q000473:pathology