title: Doughnut-shaped peptide nano-assemblies and their applications as nanoreactors.
abstract: Doughnut-shaped nanoreactors, peptide nano-doughnuts, were self-assembled from peptides and organic Au salts. We demonstrated that monodisperse Au nanocrystals were synthesized inside the cavities of peptide nano-doughnuts by the reduction of Au ions and the size of the Au nanocrystal was controlled by the cavity dimension. The Au nanocrystals inside the nano-doughnuts were extracted by destroying the nano-doughnuts via long UV irradiation (>10 h). These features may allow the peptide nano-doughnuts to be applied in the fields of nanomaterial syntheses, controlled release systems, and drug delivery.
authors.affiliation: Department of Chemistry and Biochemistry at Hunter College and the Graduate Center, The City University of New York, New York, New York 10021, USA.
authors.forename: Ramin
authors.initials: R
authors.lastname: Djalali
authors.forename: Jacopo
authors.initials: J
authors.lastname: Samson
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsui
mesh_terms: D003460:Crystallization; D006046:Gold / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D036103:Nanotechnology / Q000379:methods*; D009942:Organometallic Compounds / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry*; D011487:Protein Conformation; D017550:Spectroscopy, Fourier Transform Infrared; D014466:Ultraviolet Rays
chemical_list: D009942:Organometallic Compounds; D010455:Peptides; D006046:Gold