Treatment of canine atopic dermatitis with cetirizine, a second generation antihistamine: a single-blinded, placebo-controlled study.
Cetirizine and placebo were administered orally as individual agents to 23 dogs with atopic dermatitis. The pruritus was satisfactorily reduced in 4/22 (18%) dogs that completed the trial with cetirizine. Two dogs vomited after administration of the active drug.
Cook
Christopher P
CP
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA.
Scott
Danny W
DW
Miller
William H
WH
Kirker
J Edward
JE
Cobb
Shaun M
SM
D000284:Administration, Oral; D000818:Animals; D017332:Cetirizine / Q000009:adverse effects / Q000627:therapeutic use*; D018592:Cross-Over Studies; D003876:Dermatitis, Atopic / Q000188:drug therapy / Q000662:veterinary*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D005260:Female; D039563:Histamine H1 Antagonists, Non-Sedating / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D010919:Placebos; D011537:Pruritus / Q000188:drug therapy / Q000662:veterinary; D011897:Random Allocation; D016037:Single-Blind Method; D016896:Treatment Outcome; D014839:Vomiting / Q000139:chemically induced / Q000662:veterinary
D039563:Histamine H1 Antagonists, Non-Sedating; D010919:Placebos; D017332:Cetirizine