title: Plasma and erythrocyte magnesium, manganese, zinc, and plasma calcium levels in G-6-PD-deficient and normal male children.
abstract: Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency is the most common human enzymopathy in the world. Trace elements are important for normal hematopoiesis and can play a role in acute hemolytic anemia induced by G-6-PD deficiency. For this purpose, we studied two groups consisting of 10 male children who are G-6-PD-deficient and 12 age-matched normal male children to compare plasma and erythrocyte magnesium, manganese, zinc, and plasma calcium levels between G-6-PD-deficient and normal children. All assays were performed under normal conditions free of any oxidative attack that may result in hemolytic crisis in G-6-PD-deficient subjects. All parameters in each group did not differ significantly except for erythrocyte G-6-PD activities. These data show that plasma and erythrocyte trace element contents of G-6-PD-deficient subjects do not differ in normal conditions.
authors.affiliation: Department of Biochemistry, Akdeniz University, Antalya, Turkey.
authors.forename: Süreyya Bilmen
authors.initials: SB
authors.lastname: Sarikcioglu
authors.forename: Saadet
authors.initials: S
authors.lastname: Gümüslü
authors.forename: Nimet
authors.initials: N
authors.lastname: Uysal
authors.forename: T Aslan
authors.initials: TA
authors.lastname: Aksu
mesh_terms: D002118:Calcium / Q000097:blood*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D004912:Erythrocytes / Q000737:chemistry*; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000097:blood*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008274:Magnesium / Q000097:blood*; D008297:Male; D008345:Manganese / Q000097:blood*; D015032:Zinc / Q000097:blood*
chemical_list: D008345:Manganese; D008274:Magnesium; D015032:Zinc; D002118:Calcium