title: Massive intracavitary clot formation during cardiopulmonary bypass.
abstract: The present case report describes the spontaneous formation of blood clots in the right and left sides of the circulation, despite good anticoagulation, in a patient undergoing coronary bypass surgery. The authors hypothesize that, because the patient turned out to have positive serology for heparin-induced thrombocytopenia that was not diagnosed preoperatively, heparin-induced thrombocytopenia thrombosis may account for all findings. The clinical scenario is described in detail and potential explanations and relevance are discussed.
authors.affiliation: Dalhousie University, Department of Surgery, Halifax, Nova Scotia. jean.legare@cdha.nshealth.ca
authors.forename: Jean-Francois
authors.initials: JF
authors.lastname: Legare
authors.forename: Rakesh
authors.initials: R
authors.lastname: Arora
authors.forename: Jeremy W
authors.initials: JW
authors.lastname: Wood
mesh_terms: D000368:Aged; D000789:Angina, Unstable / Q000175:diagnosis / Q000601:surgery*; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects*; D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D017548:Echocardiography, Transesophageal; D017809:Fatal Outcome; D006493:Heparin / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D013921:Thrombocytopenia / Q000139:chemically induced*; D013927:Thrombosis / Q000139:chemically induced* / Q000000981:diagnostic imaging
chemical_list: D000925:Anticoagulants; D006493:Heparin