Leptin and liver disease: facts and presumptions.
Leptin is being recognized as a multifunctional cytokine with diverse actions on body weight, energy expenditure, glucose homeostasis, reproduction, hemopoiesis and wound repair. This commentary describes some evidences related with its possible role in liver diseases, particularly, in fat deposition, inflammation and fibrosis.
Siddiqui
Arif Rasheed
AR
Department of Gastroenterology, SIUT, Civil Hospital, Karachi. drarsid@yahoo.com
Abbas
Zaigham Ali
ZA
D006801:Humans; D020738:Leptin / Q000097:blood / Q000502:physiology*; D008103:Liver Cirrhosis / Q000097:blood / Q000503:physiopathology*; D008107:Liver Diseases / Q000097:blood / Q000503:physiopathology*
D020738:Leptin