title: Surgical management of iris defects with prosthetic iris devices.
abstract: OBJECTIVE
  To evaluate the safety and efficacy of surgical implantation of prosthetic iris devices in patients with iris deficiency.
  
  
  METHODS
  Nine patients with traumatic iris defects, congenital aniridia or iris coloboma, and surgical or optical iridectomies were included in a noncomparative case series. Cataract surgery with intraocular lens and prosthetic iris implantation was performed in 10 eyes. The visual acuity, subjective degree of glare disability, postoperative anatomic results, and intraoperative and postoperative complications were evaluated.
  
  
  RESULTS
  The mean follow-up was 17.75 months (range 4-48 months). Best-corrected visual acuity improved in nine of 10 eyes (90%) and remained unchanged in one eye. Glare subjectively improved in four of five eyes (80%) of patients complaining of glare preoperatively. All eyes achieved the desired anatomic result. Intraoperative complications included one anterior capsular tear. Postoperative complications included a short period of mild postoperative anterior uveitis in four eyes. Secondary glaucoma was absent.
  
  
  CONCLUSIONS
  In patients with iris deficiency, implantation of prosthetic iris device, and intraocular lens implant following cataract surgery appears to be safe and effective in reducing glare disability and improving visual outcomes.
authors.affiliation: Sussex Eye Hospital, Brighton and Sussex University Hospitals, Brighton, UK.
authors.forename: I
authors.initials: I
authors.lastname: Mavrikakis
authors.forename: E
authors.initials: E
authors.lastname: Mavrikakis
authors.forename: P P
authors.initials: PP
authors.lastname: Syam
authors.forename: J
authors.initials: J
authors.lastname: Bell
authors.forename: J Hickman
authors.initials: JH
authors.lastname: Casey
authors.forename: A G
authors.initials: AG
authors.lastname: Casswell
authors.forename: G P
authors.initials: GP
authors.lastname: Brittain
authors.forename: C
authors.initials: C
authors.lastname: Liu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015783:Aniridia / Q000601:surgery; D003103:Coloboma / Q000601:surgery; D005260:Female; D019466:Glare / Q000009:adverse effects; D006801:Humans; D007498:Iris / Q000293:injuries* / Q000601:surgery; D007499:Iris Diseases / Q000601:surgery*; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D019736:Prostheses and Implants; D019919:Prosthesis Implantation / Q000009:adverse effects / Q000379:methods; D012189:Retrospective Studies; D016896:Treatment Outcome; D014606:Uveitis, Anterior / Q000209:etiology; D014792:Visual Acuity