Pyridazines. Part 37: Facile solution phase combinatorial synthesis of highly substituted pyridazin-3-ones.
Arrays of polysubstituted pyridazinones were prepared through three- or four-component transformations starting from the readily accessible ene-adducts 2.
Sotelo
Eddy
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Laboratorio de Química Farmacéutica, Drug Research and Development Group, Departamento de Química Orgánica, Facultad de Farmacia, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain. qosotelo@usc.es
D001671:Biochemistry / Q000379:methods*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D010165:Palladium / Q000737:chemistry; D011724:Pyridazines / Q000138:chemical synthesis / Q000737:chemistry*
D011724:Pyridazines; D010165:Palladium