Global genetic diversity of human metapneumovirus fusion gene.
We analyzed 64 human metapneumovirus strains from eight countries. Phylogenetic analysis identified two groups (A and B, amino acid identity 93%-96%) and four subgroups. Although group A strains predominated, accounting for 69% of all strains, as many B as A strains were found in persons >3 years of age.
Boivin
Guy
G
Centre Hospitalier Universitaire de Québec and Laval University, Sainte-Foy, Quebec City, Canada. guy.boivin@crchul.ulaval.ca
Mackay
Ian
I
Sloots
Theo P
TP
Madhi
Shabir
S
Freymuth
François
F
Wolf
Dana
D
Shemer-Avni
Yonat
Y
Ludewick
Herbert
H
Gray
Gregory C
GC
LeBlanc
Eric
E
D000293:Adolescent; D000328:Adult; D000595:Amino Acid Sequence; D001483:Base Sequence; D002675:Child, Preschool; D016000:Cluster Analysis; D004279:DNA, Viral / Q000737:chemistry / Q000235:genetics; D005260:Female; D014644:Genetic Variation / Q000235:genetics; D006801:Humans; D008297:Male; D029121:Metapneumovirus / Q000235:genetics*; D008969:Molecular Sequence Data; D018184:Paramyxoviridae Infections / Q000821:virology*; D010802:Phylogeny; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D014760:Viral Fusion Proteins / Q000737:chemistry / Q000235:genetics*
D004279:DNA, Viral; D014760:Viral Fusion Proteins