Effects of aging and life-prolonging diet on thyroid regulation of protein synthesis.
The effect of thyroxin on the intensity of protein synthesis in rats of different age was studied during natural aging and in rats maintained on a low-caloric diet inhibiting aging. The intensity of protein synthesis decreased and the reaction to hormonal stimulus was absent in animals fed life-prolonging diet.
Gromakova
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Institute of Biology, V. N. Karazin National University, Kharkov. padalko@univer.kharkov.ua
Konovalenko
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D000375:Aging / Q000097:blood / Q000378:metabolism*; D000818:Animals; D001798:Blood Proteins / Q000096:biosynthesis; D031204:Caloric Restriction; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D014176:Protein Biosynthesis; D051381:Rats; D017208:Rats, Wistar; D013961:Thyroid Gland / Q000187:drug effects / Q000378:metabolism; D013974:Thyroxine / Q000097:blood / Q000494:pharmacology; D014284:Triiodothyronine / Q000097:blood
D001798:Blood Proteins; D014284:Triiodothyronine; D013974:Thyroxine