title: 3DCoffee@igs: a web server for combining sequences and structures into a multiple sequence alignment.
abstract: This paper presents 3DCoffee@igs, a web-based tool dedicated to the computation of high-quality multiple sequence alignments (MSAs). 3D-Coffee makes it possible to mix protein sequences and structures in order to increase the accuracy of the alignments. Structures can be either provided as PDB identifiers or directly uploaded into the server. Given a set of sequences and structures, pairs of structures are aligned with SAP while sequence-structure pairs are aligned with Fugue. The resulting collection of pairwise alignments is then combined into an MSA with the T-Coffee algorithm. The server and its documentation are available from http://igs-server.cnrs-mrs.fr/Tcoffee/.
authors.affiliation: Information Génomique et Structurale UPR2589-CNRS, CNRS, 31, Chemin Joseph Aiguier, 13 402 Marseille Cedex 20, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Poirot
authors.forename: Karsten
authors.initials: K
authors.lastname: Suhre
authors.forename: Chantal
authors.initials: C
authors.lastname: Abergel
authors.forename: Eamonn
authors.initials: E
authors.lastname: O'Toole
authors.forename: Cedric
authors.initials: C
authors.lastname: Notredame
mesh_terms: D020407:Internet; D011506:Proteins / Q000737:chemistry; D016415:Sequence Alignment; D020539:Sequence Analysis, Protein; D012984:Software
chemical_list: D011506:Proteins