title: Drug-induced lupus erythematosus.
abstract: Among the numerous idiopathic immune-mediated diseases that can be drug-induced, such as pemphigus, psoriasis, lichen, etc, drug-induced lupus is the most widely commented upon and investigated. The terms drug-induced lupus (DIL) and drug-induced lupus erythematosus (DILE) are preferred, but other ones are also used--drug-related lupus, lupus-like syndrome, and lupus erythematosus medicamentosus. This review discusses the general issues in DILE, such as pathogenic mechanisms, clinical forms, and diagnostic criteria, and provides more detailed information for some of the implicated drugs: minocycline, statins, terbinafine, etc.
authors.affiliation: Department of Dermatology and Venereology, Sofia Faculty of Medicine, Sofia, Bulgaria. dimitar_antonov@doctor.bg
authors.forename: Dimitar
authors.initials: D
authors.lastname: Antonov
authors.forename: Jana
authors.initials: J
authors.lastname: Kazandjieva
authors.forename: Doncho
authors.initials: D
authors.lastname: Etugov
authors.forename: Dimitar
authors.initials: D
authors.lastname: Gospodinov
authors.forename: Nikolai
authors.initials: N
authors.lastname: Tsankov
mesh_terms: D003875:Drug Eruptions / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000139:chemically induced / Q000175:diagnosis*