title: Synthesis and optical resolution of 9,9'-spirobifluorene-1,1'-diol.
abstract: [reaction: see text] 9,9'-Spirobifluorene-1,1'-diol (SBIFOL) was conveniently synthesized from 1,2-dibromobenzene and 3-bromoanisole in high yield. Both enantiomers of SBIFOL were obtained in 99% ee by inclusion resolution with 2,3-dimethoxy-N,N,N',N'-tetracyclohexylsuccinamide. The absolute configurations were determined by X-ray analysis of a single crystal of molecular complex.
authors.affiliation: State Key Laboratory and Institute of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Cheng
authors.forename: Guo-Hua
authors.initials: GH
authors.lastname: Hou
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Xie
authors.forename: Qi-Lin
authors.initials: QL
authors.lastname: Zhou