title: [Protection of tooth protecting spray against dental carries].
abstract: OBJECTIVE
  To investigate the growth, adherence and soul production of streptococcus mutans incubated with olitin tooth protecting spray and the effect of specific sample against dental caries.
  
  
  METHODS
  Streptococcus mutans were cultured with the sample of Olitin tooth protecting spray. After culturing, S. mutans were observed by Gram stain and by spectrophotometer, and the percentages of the adherent S. mutans were calculated. 40 Wistar rats were divided into 4 groups: group A was control group; group B,C,D was low, middle, high test group respectively. All test groups received samples. The sum of the caries scores was assessed by the Keyes' procedure.
  
  
  RESULTS
  The sample did not inhibit the growth of S. mutans, but the long chain was occurred. The adherence of S. mutans cells on the glass was decrease, the pH value was increase to above 6.0. There was a significant lower mean of caries score of test group than control group.
  
  
  CONCLUSIONS
  The sample can prevent the development of dental caries in this experiment. The mechanism may relate with the decrease of adherence of S. mutans.
authors.affiliation: Hubei Center for Disease Control and Prevention, Wuhan 430079, China.
authors.forename: Yuhong
authors.initials: Y
authors.lastname: Li
authors.forename: Xinlan
authors.initials: X
authors.lastname: Li
authors.forename: Chenrui
authors.initials: C
authors.lastname: Gong
authors.forename: Guoqin
authors.initials: G
authors.lastname: Yi
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001422:Bacterial Adhesion / Q000187:drug effects*; D002327:Cariostatic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D003731:Dental Caries / Q000517:prevention & control*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013295:Streptococcus mutans / Q000187:drug effects*
chemical_list: D002327:Cariostatic Agents