title: Hypertrophic cardiomyopathy associated with left ventricular aneurysm and normal coronary arteries: Case study indicating genetic tendencies of cardiomyopathy.
abstract: A 50-year-old man presented with hypertrophic obstructive cardiomyopathy (HOC) associated with a left ventricular aneurysm and normal coronary arteries. His history revealed no evidence of myocardial infarction or atypical angina. Physical examination disclosed HOC but did not suggest the presence of an aneurysm. Although the patient was treated medically, heart failure ensued, and he died suddenly while working his farm. Subsequent investigation of the patient's family revealed that three of his five children were also affected by cardiomyopathy, which was especially pronounced in the eldest, a 22-year-old man. The possible hemodynamic relationship between HOC and left ventricular aneurysm is discussed, along with probable indications. The role of left ventricular aneurysm is also presented in relation to the natural history of the disease.
authors.affiliation: Servicio de Cardiologia, Hospital "Primero de Octubre," Madrid, Spain.
authors.forename: C Saenz
authors.initials: CS
authors.lastname: De La Calzada
authors.forename: A Llovet
authors.initials: AL
authors.lastname: Verdugo
authors.forename: J Tascon
authors.initials: JT
authors.lastname: Perez
authors.forename: C Castro
authors.initials: CC
authors.lastname: Alcaine
authors.forename: A Sanchez
authors.initials: AS
authors.lastname: Fernandez