Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction.
Sixty-nine patients who underwent primary percutaneous coronary intervention within 12 hours after onset of acute myocardial infarction were randomized to receive intracoronary injection of autologous bone marrow mesenchymal stem cell or standard saline. Several imagining techniques demonstrated that bone marrow mesenchymal stem cells significantly improved left ventricular function.
Chen
Shao-liang
SL
Division of Cardiology, Nanjing First Hospital, Nanjing University, Nanjing, Jiangsu Province, China. chmengx@126.com
Fang
Wu-wang
WW
Ye
Fei
F
Liu
Yu-Hao
YH
Qian
Jun
J
Shan
Shou-jie
SJ
Zhang
Jun-jie
JJ
Chunhua
Robert Zhao
RZ
Liao
Lian-ming
LM
Lin
Song
S
Sun
Jing-ping
JP
D015906:Angioplasty, Balloon, Coronary; D004452:Echocardiography; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D059630:Mesenchymal Stem Cells; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000628:therapy*; D033581:Stem Cell Transplantation; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000628:therapy*; D020257:Ventricular Remodeling