Adenosine-induced second window of protection is mediated by inhibition of mitochondrial permeability transition pore opening at the time of reperfusion.
Hausenloy
Derek J
DJ
Yellon
Derek M
DM
D000241:Adenosine / Q000378:metabolism*; D000818:Animals; D007473:Ion Channels / Q000037:antagonists & inhibitors*; D019157:Ischemic Preconditioning, Myocardial; D008297:Male; D008929:Mitochondria, Heart / Q000378:metabolism; D033681:Mitochondrial Membrane Transport Proteins; D000083162:Mitochondrial Permeability Transition Pore; D015425:Myocardial Reperfusion; D051381:Rats; D017207:Rats, Sprague-Dawley
D007473:Ion Channels; D033681:Mitochondrial Membrane Transport Proteins; D000083162:Mitochondrial Permeability Transition Pore; D000241:Adenosine