title: Solitary intracranial metastasis of follicular carcinoma of the thyroid gland clinically mimicking a meningioma.
abstract: We describe a rare case of solitary metastasis of follicular carcinoma of the thyroid gland into the petroclival region in a 58-year-old woman. The metastasis was the first and only manifestation of the disease. The histology of the tumor, differential diagnosis and clinical course are discussed. In a few similar cases described so far the tumor was always a well or moderately differentiated follicular carcinoma located in the petroclival region. As in this presentation, these cases also clinically mimic a meningioma. The differential diagnosis includes adenoma of the thyroid gland and thyroid gland dystopia. We demonstrated the primary focus of carcinoma within the thyroid after its detailed examination initiated by our finding. The clinical outcome of such rare cases is usually excellent, much better than in metastases of papillary carcinoma into the brain.
authors.affiliation: Department of Pathology & Laboratory of Molecular Pathology Faculty of Medicine, Palacký University, Olomouc. jiri.ehrmann@tiscali.cz
authors.forename: J
authors.initials: J
authors.lastname: Ehrmann
authors.forename: M
authors.initials: M
authors.lastname: Dusková
authors.forename: J
authors.initials: J
authors.lastname: Machac
authors.forename: V
authors.initials: V
authors.lastname: Benýsek
authors.forename: J
authors.initials: J
authors.lastname: Hobza
authors.forename: Z
authors.initials: Z
authors.lastname: Kolár
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000175:diagnosis / Q000556:secondary*; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000175:diagnosis; D008579:Meningioma / Q000175:diagnosis; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000473:pathology*