Expression of testis specific ankyrin repeat and SOCS box-containing 17 gene.
Human ASB-17 (Ankyrin Repeat and SOCS Box-containing 17) is a recently identified gene belonging to the ASB family, isolated from testis cDNA library. Human ASB-17 is expressed exclusively in testis among 16 tissues, revealed by Northern blot. Mouse Asb-17 was shown to be expressed from the third week post birth to adult by semi-quantitative RT-PCR analysis. In situ hybridization on frozen sections demonstrated that Asb-17 is expressed in spermatogenic cells in adult mouse, but not in Leydig cell and epididymis in adult mouse. ASB-17 proteins are highly conserved in mammals including human, mouse, rat, Canis familiaris and Macaca fascicularis.
Guo
J H
JH
State Key Laboratory of Genetic Engineering, Institute of Genetics, Fudan University, Shanghai, People's Republic of China.
Saiyin
H
H
Wei
Y H
YH
Chen
S
S
Chen
L
L
Bi
G
G
Ma
L J
LJ
Zhou
G J
GJ
Huang
C Q
CQ
Yu
L
L
Dai
L
L
D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics*; D000595:Amino Acid Sequence; D000818:Animals; D017089:Ankyrin Repeat / Q000235:genetics*; D015152:Blotting, Northern; D016207:Cytokines / Q000378:metabolism; D005786:Gene Expression Regulation; D015723:Gene Library; D006801:Humans; D017403:In Situ Hybridization; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D020133:Reverse Transcriptase Polymerase Chain Reaction; D020539:Sequence Analysis, Protein; D015398:Signal Transduction; D050826:Suppressor of Cytokine Signaling Proteins; D013737:Testis / Q000378:metabolism*
D048868:Adaptor Proteins, Signal Transducing; C434933:Asb1 protein, mouse; D016207:Cytokines; D050826:Suppressor of Cytokine Signaling Proteins