Effectiveness of sirolimus-Eluting stent implantation for coronary narrowings <50% in diameter.
The long-term efficacy of percutaneous coronary intervention for mildly obstructive coronary narrowings is limited by the occurrence of restenosis, limiting the applicability of this therapy for these lesions. The present study reports on a consecutive series of 20 patients treated with sirolimus-eluting stent implantation for 23 angiographically mild de novo lesions (defined as a diameter stenosis <50% by quantitative coronary angiography). At a mean follow-up of 399 +/- 120 days, the survival-free of major adverse events was 95%, with no patient requiring target lesion revascularization.
Hoye
Angela
A
Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands.
Lemos
Pedro A
PA
Arampatzis
Chourmouzios A
CA
Saia
Francesco
F
Tanabe
Kengo
K
Degertekin
Muzaffer
M
Daemen
Joost
J
Smits
Pieter C
PC
McFadden
Eugene
E
Hofma
Sjoerd H
SH
Sianos
Georgios
G
de Feyter
Pim
P
Giessen
Willem J
WJ
van Domburg
Ron T
RT
Serruys
Patrick W
PW
D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D020123:Sirolimus / Q000008:administration & dosage*; D015607:Stents; D016896:Treatment Outcome
D007166:Immunosuppressive Agents; D020123:Sirolimus