title: [Effect of complementary food supplements on anemia in infant and young children].
abstract: OBJECTIVE
  To investigate the effect of complementary food supplements with protein and multi-micronutrients on hemoglobin and anemia in infant and young children.
  
  
  METHODS
  In 5 poor county of Gansu province, children aged 4-12 months were enrolled and divided into two groups, protein and micronutrient were supplemented in Formula I group, all children were observed until they were 24 months old. Every 6 months, a massive dose of Vitamin A was supplemented to all children, hemoglobin tests were done at the same time.
  
  
  RESULTS
  At baseline survey, there are no differences in hemoglobin and prevalence of anemia between two groups. During the follow-up of 12 months supplementation, Hemoglobin increase of the Formula I group is significantly higher than Formula II group(P < 0.0005), prevalence of anemia reduce obviously and there is statistically different between the two groups. Hemoglobin increase of the two groups are significantly different until all children are 24 months old(P = 0.006).
  
  
  CONCLUSIONS
  Supplemented micronutrient and large-dose Vitamin A can increase hemoglobin and decrease prevalence of anemia in infant and young children.
authors.affiliation: National Center for Public Health Surveillance and Information Services, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
authors.forename: Yuying
authors.initials: Y
authors.lastname: Wang
authors.forename: Chunming
authors.initials: C
authors.lastname: Chen
authors.forename: Mei
authors.initials: M
authors.lastname: Jia
authors.forename: Jianping
authors.initials: J
authors.lastname: Fang
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000517:prevention & control*; D004044:Dietary Proteins / Q000008:administration & dosage; D005260:Female; D005527:Food, Fortified; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007223:Infant; D019266:Iron, Dietary / Q000008:administration & dosage; D008297:Male; D018977:Micronutrients / Q000008:administration & dosage*; D014801:Vitamin A / Q000008:administration & dosage*
chemical_list: D004044:Dietary Proteins; D006454:Hemoglobins; D019266:Iron, Dietary; D018977:Micronutrients; D014801:Vitamin A