Conservative management of pulmonary lymphangioleiomyomatosis and tuberous sclerosis complicated by renal angiomyolipomas in pregnancy.
Both pulmonary lymphangioleiomyomatosis and tuberous sclerosis are rare diseases. The optimal management in pregnancy is unclear. A primigravida with pulmonary lymphangioleiomyomatosis and tuberous sclerosis complicated by worsening renal function secondary to angiomyolipomas was managed conservatively. Favorable maternal and neonatal outcomes were achieved. Pulmonary lymphangioleiomyomatosis is a consideration in tuberous sclerosis patients with respiratory symptoms. Tuberous sclerosis patients with pulmonary lymphangioleiomyomatosis require cautious and calculated expectant management in an effort to avoid adverse outcomes.
Cleary-Goldman
J
J
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Columbia Presbyterian Medical Center, New York, New York, USA.
Sanghvi
A V
AV
Nakhuda
G S
GS
Robinson
J N
JN
D000328:Adult; D018207:Angiomyolipoma / Q000150:complications* / Q000628:therapy; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications* / Q000628:therapy; D008175:Lung Neoplasms / Q000150:complications* / Q000628:therapy; D018192:Lymphangioleiomyomatosis / Q000150:complications* / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D014402:Tuberous Sclerosis / Q000150:complications*