title: [Clinical analysis of the application of Diomed-25 laser in treatment of vocal cord leukoplakia in 30 cases].
abstract: OBJECTIVE
  To explore the effect of Diomed-25 semi-conductive laser in treatment of vocal cord leukoplakia.
  
  
  METHODS
  From 1997 to 2001, 30 patients with vocal cord leukoplakia were operated in our hospital by Diomed-25 laser, acoustic analysis were compared and studied before and after operation. All the patients were followed up, ranging from 1 to 5 years.
  
  
  RESULTS
  There were 16 cases of simple leukoplakia and 14 cases with mild, moderate or severe atypical hyperplasia in this study. None of simple leukoplakia and mild atypical hyperplasia had malignant change, but 2 cases had malignant change who were the cases with moderate and severe atypical hyperplasia respectively. Acoustic analysis showed significant difference between preoperation and postoperation group (P < 0.05).
  
  
  CONCLUSIONS
  The Diomed-25 laser was proved valuable in treating patients with vocal cord leukoplakia.
authors.affiliation: Department of Otolaryngology, Changhai Hospital, Second Military Medical University, Shanghai, 200433, China.
authors.forename: Guangbin
authors.initials: G
authors.lastname: Sun
authors.forename: Shuimiao
authors.initials: S
authors.lastname: Zhou
authors.forename: Wu
authors.initials: W
authors.lastname: Wen
authors.forename: Zhaoji
authors.initials: Z
authors.lastname: Li
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Shen
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000601:surgery*; D053685:Laser Therapy; D007971:Leukoplakia / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000601:surgery; D014827:Vocal Cords / Q000601:surgery*