Is 100% oxygen necessary for the resuscitation of newborn infants?
This paper reproduces in detail the debate 'pro-and-con' regarding the use of 100% oxygen or room air in the resuscitation of the asphyxiated newly born infants, celebrated in Oslo at the 2002 European Association of Perinatal Medicine (EAPM) meeting, in which both co-authors participated as featured speakers. The authors describe their arguments which are based on medical tradition, clinical experience, basic science, and prospective randomized and pseudo-randomized clinical studies that have been reported in the past years. Both authors stress the importance of the long-term consequences of the use of high oxygen concentrations in the perinatal period and conclude that there is a need for further research in the way of ample prospective randomized clinical trials.
Niermeyer
S
S
Department of Pediatrics, University of Colorado Health Sciences Center, The Children's Hospital, Denver, Colorado 80218-1088, USA.
Vento
M
M
D000388:Air; D000818:Animals; D001238:Asphyxia Neonatorum / Q000503:physiopathology / Q000628:therapy*; D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D006801:Humans; D007231:Infant, Newborn; D010100:Oxygen / Q000008:administration & dosage / Q000009:adverse effects / Q000378:metabolism; D010102:Oxygen Inhalation Therapy; D017410:Practice Guidelines as Topic; D012449:Safety
D010100:Oxygen