title: Quantification of stenotic mitral valve area with magnetic resonance imaging and comparison with Doppler ultrasound.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the reliability of the pressure half-time (PHT) method for estimating mitral valve areas (MVAs) by velocity-encoded cardiovascular magnetic resonance (VE-CMR) and to compare the method with paired Doppler ultrasound.
  
  
  BACKGROUND
  The pressure half-time Doppler echocardiography method is a practical technique for clinical evaluation of mitral stenosis. As CMR continues evolving as a routine clinical tool, its use for estimating MVA requires thorough evaluation.
  
  
  METHODS
  Seventeen patients with mitral stenosis underwent echocardiography and CMR. Using VE-CMR, MVA was estimated by PHT method. Additionally, peak E and peak A velocities were defined. Interobserver repeatability of VE-CMR was evaluated.
  
  
  RESULTS
  By Doppler, MVAs ranged from 0.87 to 4.49 cm2; by CMR, 0.91 to 2.70 cm2, correlating well between modalities (r = 0.86). The correlation coefficient for peak E and peak A between modalities was 0.81 and 0.89, respectively. Velocity-encoded CMR data analysis provided robust, repeatable estimates of peak E, peak A, and MVA (r = 0.99, 0.99, and 0.96, respectively).
  
  
  CONCLUSIONS
  Velocity-encoded cardiovascular magnetic resonance can be used routinely as a robust tool to quantify MVA via mitral flow velocity analysis with PHT method.
authors.affiliation: Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
authors.forename: Shiow Jiuan
authors.initials: SJ
authors.lastname: Lin
authors.forename: Peggy A
authors.initials: PA
authors.lastname: Brown
authors.forename: Mary P
authors.initials: MP
authors.lastname: Watkins
authors.forename: Todd A
authors.initials: TA
authors.lastname: Williams
authors.forename: Katherine A
authors.initials: KA
authors.lastname: Lehr
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Gregory M
authors.initials: GM
authors.lastname: Lanza
authors.forename: Samuel A
authors.initials: SA
authors.lastname: Wickline
authors.forename: Shelton D
authors.initials: SD
authors.lastname: Caruthers
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004452:Echocardiography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging* / Q000473:pathology; D008946:Mitral Valve Stenosis / Q000175:diagnosis* / Q000453:epidemiology; D015588:Observer Variation; D011859:Radiography; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D013223:Statistics as Topic; D018608:Ultrasonography, Doppler