[Use of cytostatic therapy with 5-fluorouracil in surgery of glaucoma].
Possibilities, conditions and outlooks of using a 5% fluorouracil solution, as subconjunctival injections after antiglaucomatous interventions and as intraoperative applications in the trabecular area, were studied in 131 patients (143 eyes) with uncompensated developed and advanced glaucoma. The results of clinical examinations showed a high efficiency of using fluorouracil after antiglaucomatous interventions to ensure a long-lasting hypotensive effect. Two injections made in the early postoperative period did not entail any complications and were sufficient to maintain the surgical effect.
Shmyreva
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Mostovoĭ
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D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000627:therapeutic use*; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use*; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007430:Intraoperative Care; D008875:Middle Aged; D011182:Postoperative Care; D012086:Reoperation; D012590:Sclera / Q000601:surgery; D013997:Time Factors; D014129:Trabecular Meshwork; D014130:Trabeculectomy
D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil