title: Is supra-Baxter resuscitation in burn patients a new phenomenon?
abstract: Baxter described the use of 4 cm3/kg/%TBSA as a guideline for fluid resuscitation after burns. However, recent studies have shown that, at the present time, patients generally receive greater than the "Baxter" formula. Pruitt has called this phenomenon "fluid creep," and it has the potential for significant consequences including abdominal and extremity compartment syndromes and severe pulmonary insults. The purpose of this paper is to determine if this supra-Baxter resuscitation is a new phenomenon. We performed a retrospective chart review with two cohorts of patients. Group 1 consisted of 11 patients admitted between 1975 and 1978 to our burn center. Group 2 consisted of 11 patients admitted to our burn center in 2000 who were matched for age, sex, and percent total body surface area burned. Group 1 received 3.6 +/- 1.1 cm3/kg/% TBSA of fluid in the first 24 h. Group 2 received 8.0 +/- 2.5 cm3/kg/% TBSA, which is 100% more than the Baxter formula. There was no difference in the median age, weight, or 24-h urine output between the two groups. Our data demonstrate that the "fluid creep" phenomenon is relatively new.
authors.affiliation: Division of Plastic Surgery, Department of Surgery, Harborview Medical Center, University of Washington, Mailstop 359796, 325 Ninth Avenue, Seattle, WA 98104, USA.
authors.forename: Jeffrey B
authors.initials: JB
authors.lastname: Friedrich
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Sullivan
authors.forename: Loren H
authors.initials: LH
authors.lastname: Engrav
authors.forename: Kurt A
authors.initials: KA
authors.lastname: Round
authors.forename: Carolyn B
authors.initials: CB
authors.lastname: Blayney
authors.forename: Gretchen J
authors.initials: GJ
authors.lastname: Carrougher
authors.forename: David M
authors.initials: DM
authors.lastname: Heimbach
authors.forename: Shari
authors.initials: S
authors.lastname: Honari
authors.forename: Matthew B
authors.initials: MB
authors.lastname: Klein
authors.forename: Nicole S
authors.initials: NS
authors.lastname: Gibran
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002056:Burns / Q000473:pathology / Q000628:therapy*; D000077324:Crystalloid Solutions; D005260:Female; D005440:Fluid Therapy / Q000379:methods*; D019983:Guideline Adherence; D006801:Humans; D007552:Isotonic Solutions; D008297:Male; D008875:Middle Aged; D010952:Plasma Substitutes / Q000008:administration & dosage; D017410:Practice Guidelines as Topic; D015532:Rehydration Solutions / Q000008:administration & dosage*; D012189:Retrospective Studies; D018709:Statistics, Nonparametric
chemical_list: D000077324:Crystalloid Solutions; D007552:Isotonic Solutions; D010952:Plasma Substitutes; D015532:Rehydration Solutions