Relation between depressive symptoms and treadmill exercise capacity in the Heart and Soul Study.
To examine the association between depressive symptoms and exercise capacity, we performed a cross-sectional study of 944 outpatients with stable coronary artery disease and found that the presence of depressive symptoms was independently associated with poor exercise capacity (<5 MET tasks achieved; adjusted odds ratio 1.8, 95% confidence interval 1.1 to 2.7, p = 0.01). Depressive symptoms should be considered in the differential diagnosis of poor exercise capacity.
Ruo
Bernice
B
Section of General Internal Medicine, VA Medical Center, and Department of Medicine, University of California, San Francisco, USA. berniceruo@post.harvard.edu
Rumsfeld
John S
JS
Pipkin
Sharon
S
Whooley
Mary A
MA
D000368:Aged; D002318:Cardiovascular Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D015331:Cohort Studies; D003863:Depression / Q000150:complications / Q000503:physiopathology*; D004452:Echocardiography; D005080:Exercise Test; D005260:Female; D006334:Heart Function Tests; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012495:San Francisco; D018434:Sickness Impact Profile