[Resolution of Ménétrier's disease after eradication of Helicobacter pylori infection].
Ménétrier's disease is an infrequent clinical entity characterized by thickening of the gastric folds secondary to hyperplasia of the foveolar mucosa cells, frequently associated with loss of enteric proteins and hypoalbuminemia. Its etiology is unknown, although in the last few years it has been related to Helicobacter pylori infection. We present the case of a 38-year-old man with protein-losing gastroenteropathy caused by Ménétrier's disease, in whom eradication of H. pylori infection was followed by symptom improvement and resolution of hypoalbuminemia. In agreement with the criteria of other authors, we investigate the presence of H. pylori infection in all patients with Ménétrier's disease. When positive, the first-line treatment consists of eradication therapy.
Santolaria Piedrafita
S
S
Sección de Aparato Digestivo, Hospital San Jorge, Huesca, Spain. ssantolaria@able.es
Conde García
R
R
Abascal Agorreta
M
M
Domínguez Torres
I
I
Ducóns García
J
J
Guirao Larrañaga
R
R
Montoro Huguet
M
M
D000328:Adult; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D005753:Gastric Mucosa / Q000382:microbiology; D005758:Gastritis, Hypertrophic / Q000188:drug therapy* / Q000209:etiology; D016481:Helicobacter Infections / Q000150:complications / Q000188:drug therapy*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D011504:Protein-Losing Enteropathies / Q000209:etiology; D016896:Treatment Outcome
D000897:Anti-Ulcer Agents