title: Mitral valve repair in idiopathic hypereosinophilic syndrome.
abstract: Idiopathic hypereosinophilic syndrome is a rare systemic disease than can cause multiple organ failure by eosinophilic infiltration. Cardiac involvement is characterized by endocardial fibrosis and overlying thrombus, leading to restrictive cardiomyopathy and valvular dysfunction. Surgical experience of patients with mitral dysfunction caused by this syndrome is limited, and valvular replacement is most often performed. Mechanical valvular replacement has a high incidence of recurrent obstructive thrombosis, and replacement with a bioprosthesis is recommended, despite associated restrictive cardiomyopathy. A patient is described who presented with mitral insufficiency associated with idiopathic hypereosinophilic syndrome, and underwent mitral valve repair.
authors.affiliation: Department of Cardiothoracic Surgery, Hôpital Robert Debré, Avenue du général Koenig, 51100 Reims, France. jffuzellier@aol.com
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Fuzellier
authors.forename: Laurent
authors.initials: L
authors.lastname: Chapoutot
authors.forename: Pierre-Frederic
authors.initials: PF
authors.lastname: Torossian
mesh_terms: D000368:Aged; D001705:Bioprosthesis; D006350:Heart Valve Prosthesis; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications*; D008297:Male; D008943:Mitral Valve / Q000601:surgery; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000601:surgery*