Validity of antenatal diagnosis of intrauterine growth restriction by umbilical Doppler waveform index.
OBJECTIVE
To evaluate the validity of systolic/diastolic (S/D) ratio of the umbilical artery in predicting intrauterine growth restriction (IUGR).


METHODS
Diagnostic test study.


METHODS
Maharaj Nakorn Chiang Mai Hospital, Chiang Mai University.


METHODS
Two hundred and twelve singleton pregnancies between 30 and 42 weeks' gestation with clinical suspicion of IUGR were recruited and followed-up between December 1st 1995 and June 30th 1998. They were sonographically examined for routine fetal biometry and S/D ratio of umbilical artery Doppler waveform measurement within 14 days of delivery. All of them had an accurate date of last menstrual period and were between 30-42 weeks' gestation.


METHODS
The umbilical artery S/D ratio was obtained by the same experienced sonographer, using the same ultrasound machine, Aloka 680EX, (Tokyo, Japan). The S/D ratio of 3 or greater was considered abnormal, predicting IUGR prenatally for every gestational week. IUGR was defined as low birth weight of less than the 10th percentile of the standard birth weight curve of Maharaj Nakorn Chiang Mai Hospital.


METHODS
Sensitivity specificity positive predictive value and negative predictive value.


RESULTS
The prevalence of IUGR among the study group was 50.9%. The S/D ratio of 3 or greater for predicting of IUGR gave the sensitivity, specificity, positive predictive value, and negative predictive value of 52.96%, 78.85%, 74.42% and 65.08%, respectively.


CONCLUSIONS
The umbilical artery S/D ratio has relatively low sensitivity and is not a suitable test for IUGR screening. However, the specificity is rather high and it may be helpful in combination with other parameters.
Chanprapaph
Pharuhas
P
Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Thailand. pchanpra@mail.med.cmu.ac.th
Tongsong
Theera
T
Siriaree
Sitthicha
S
D000293:Adolescent; D000328:Adult; D003971:Diastole; D005260:Female; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging*; D006801:Humans; D008875:Middle Aged; D011237:Predictive Value of Tests; D011247:Pregnancy; D012039:Regional Blood Flow; D015203:Reproducibility of Results; D013599:Systole; D013785:Thailand; D018615:Ultrasonography, Doppler, Color; D016216:Ultrasonography, Prenatal; D014469:Umbilical Arteries / Q000000981:diagnostic imaging* / Q000502:physiology*