[Obstructive sleep apnea syndrome and hypothyroidism (a report of three cases)].
OBJECTIVE
To explore the relationship between obstructive sleep apnea syndrome (OSAS) and hypothyroidism, and to discuss the management experience.


METHODS
Three cases of severity OSAS with hypothyroidism were reported and relevant literatures were reviewed. One patient underwent continuous positive airway pressure (CPAP), one patient was performed uvulopalatopharyngoplasty(UPPP), and one case is in follow-up now.


RESULTS
Thyroxine replacement therapy was effective in improving symptoms and nocturnal sleep apnea.


CONCLUSIONS
Hypothyroidism probably plays a significant role in the pathogenesis of obstructive sleep apnea, the satisfactory results would be obtained by thyroxine replacement therapy, CPAP or surgical treatment can be used as adjuvant therapy in patients with this disease.
Jiang
Guangfeng
G
Department of Otolaryngology, Affiliated Hospital of Medical College Qingdao University, Qingdao, 266003, China.
Li
Na
N
Sun
Yan
Y
D006801:Humans; D007037:Hypothyroidism / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011175:Positive-Pressure Respiration; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000628:therapy; D013974:Thyroxine / Q000627:therapeutic use; D014609:Uvula / Q000601:surgery
D013974:Thyroxine