[Pharmacotherapy of acute tonsillitis-pharyngitis in ambulatory practice: results of a multicenter pharmaco-epidemiological study].
OBJECTIVE
To analyse current practice of pharmacotherapy (PT) in outpatient treatment of acute tonsillopharyngitis (ATP) in different regions of Russia.


METHODS
Case reports for 1333 outpatients (493 male and 840 female, age 16-76 years) with ATP from 7 cities of Russia have been studied. Each ATP case was documented on a special chart to contain the following information: demographic data, history of the disease, bacteriological findings, PT regimens, complications, treatment outcomes.


RESULTS
PT of ATP was made primarily with antibiotics. Most frequent of them was ampicillin (about half the cases). Further antibiotics by frequency of use were: erythromycin, ciprofloxacin, doxicyclin, amoxicillin, midecamycin, ampicillin/oxacillin. Among other drugs, wide use was registered of antihistamine drugs, throat disease drugs, analgetic and antipiretic drugs, vitamins. Bacteriological examinations were conducted rarely.


CONCLUSIONS
The problems of PT of ATP patients consist in overuse of systemic antibiotics as a result of adequate differential diagnosis of this infection and choice of antibiotics without consideration of current recommendations on the treatment of streptococcal ATP.
Kozlov
S N
SN
Strachunskiĭ
L S
LS
Rachina
S A
SA
Dmitrenok
O V
OV
Iliushchenko
L A
LA
Kuzin
V B
VB
Ortenberg
E A
EA
Paliutin
Sh Kh
ShKh
Sosonnaia
N A
NA
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000553:Ambulatory Care; D000700:Analgesics / Q000008:administration & dosage / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004363:Drug Utilization; D005260:Female; D006634:Histamine H1 Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D010612:Pharyngitis / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology; D012426:Russia / Q000453:epidemiology; D014069:Tonsillitis / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology; D016896:Treatment Outcome; D014815:Vitamins / Q000008:administration & dosage / Q000627:therapeutic use
D000700:Analgesics; D000900:Anti-Bacterial Agents; D006634:Histamine H1 Antagonists; D014815:Vitamins