Effects of bupivacaine enantiomers and ropivacaine on vasorelaxation mediated by adenosine triphosphate-sensitive K(+) channels in the rat aorta.
Dojo
Mayuko
M
Department of Anesthesiology, Wakayama Medical University, Wakayama, Japan.
Kinoshita
Hiroyuki
H
Nakahata
Katsutoshi
K
Kimoto
Yoshiki
Y
Hatano
Yoshio
Y
D000577:Amides / Q000737:chemistry / Q000494:pharmacology*; D000779:Anesthetics, Local / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D001013:Aorta, Thoracic / Q000187:drug effects*; D002045:Bupivacaine / Q000737:chemistry / Q000494:pharmacology*; D019806:Cromakalim / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004730:Endothelium, Vascular / Q000502:physiology; D066298:In Vitro Techniques; D008297:Male; D008565:Membrane Proteins / Q000187:drug effects*; D009131:Muscle, Smooth, Vascular / Q000187:drug effects*; D010208:Papaverine / Q000494:pharmacology; D015221:Potassium Channels; D051381:Rats; D017208:Rats, Wistar; D000077212:Ropivacaine; D013237:Stereoisomerism; D014664:Vasodilation / Q000187:drug effects*; D014665:Vasodilator Agents / Q000494:pharmacology
D000577:Amides; D000779:Anesthetics, Local; D008565:Membrane Proteins; D015221:Potassium Channels; D014665:Vasodilator Agents; C117780:mitochondrial K(ATP) channel; D019806:Cromakalim; D000077212:Ropivacaine; D010208:Papaverine; D002045:Bupivacaine