title: Within-herd spread of contagious bovine pleuropneumonia in Ethiopian highlands.
abstract: Contagious bovine pleuropneumonia (CBPP) is a major threat for cattle health and production in Africa. This disease is caused by the small-colony type of Mycoplasma mycoides subspecies mycoides (MmmSC). Transmission occurs from direct and repeated contacts between sick and healthy animals. Veterinary services recently reported a resurgence of CBPP in the province of West Wellega, in the Ethiopian highlands. A research program was set up to estimate the epidemiological parameters of the within-herd infection spread. A follow-up survey was implemented in 71 sampled herds of the Boji district (West Wellega province). Fifteen herds were classified as newly infected and used in a serological- and clinical-incidence study. The overall 16-month cumulative sero-incidence risk was 34%. Clinical cases were recorded for 39% of the seropositive cattle; case-fatality risk was 13%. There was no evidence of benefit on infection spread of CBPP-control measures used locally by farmers (isolation or antibiotic treatments of sick animals). This might be related to a lack of power in the statistical analyses or to a quality problem for the medications used (and more generally, for health-care delivery in the Boji district).
authors.affiliation: Centre de Coopération Internationale en Recherche Agronomique pour le Développement, Campus International de Baillarguet, 34398 Montpellier 5, France. m.lesnoff@cgiar.org
authors.forename: Matthieu
authors.initials: M
authors.lastname: Lesnoff
authors.forename: Géraud
authors.initials: G
authors.lastname: Laval
authors.forename: Pascal
authors.initials: P
authors.lastname: Bonnet
authors.forename: Sintayehu
authors.initials: S
authors.lastname: Abdicho
authors.forename: Asseguid
authors.initials: A
authors.lastname: Workalemahu
authors.forename: Daniel
authors.initials: D
authors.lastname: Kifle
authors.forename: Armelle
authors.initials: A
authors.lastname: Peyraud
authors.forename: Renaud
authors.initials: R
authors.lastname: Lancelot
authors.forename: François
authors.initials: F
authors.lastname: Thiaucourt
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology* / Q000209:etiology / Q000635:transmission*; D018562:Disease Transmission, Infectious / Q000662:veterinary*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005002:Ethiopia / Q000453:epidemiology; D015994:Incidence; D009176:Mycoplasma mycoides / Q000276:immunology / Q000302:isolation & purification; D011002:Pleuropneumonia, Contagious / Q000453:epidemiology* / Q000209:etiology / Q000635:transmission*
chemical_list: D000907:Antibodies, Bacterial