title: Nonfamilial juvenile polyposis coli in a child: report of a case.
abstract: Juvenile polyposis coli (JPC) is an uncommon condition, manifesting as hamartomatous gastrointestinal polyposis with potential malignancy. This report describes a 15-month-old girl who was diagnosed to have nonfamilial JPC accompanied by macrocephaly, clubbed fingers, and mental retardation. Radiography of the colon by a barium enema and total colonoscopy demonstrated numerous colonic polyps. A barium meal study did not show any abnormality in the stomach, duodenum, or small intestine. She died at 6 years of age from hemorrhagic shock due to massive lower gastrointestinal bleeding associated with a rectal prolapse. The related literature is reviewed, and the treatments and complications of JPC in children are also discussed. We emphasize that family members of patients diagnosed with juvenile polyposis should be questioned and undergo appropriate examinations of the entire intestine from the stomach to the rectum.
authors.affiliation: Department of Pediatric Surgery, First Surgery, Endoscopy and Pathology, Hokkaido University, School of Medicine, N 15, W 7, Kita-ku, Sapporo 060-8638, Japan.
authors.forename: Tadao
authors.initials: T
authors.lastname: Okada
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Sasaki
authors.forename: Shinya
authors.initials: S
authors.lastname: Ueki
authors.forename: Shinichi
authors.initials: S
authors.lastname: Nakagawa
authors.forename: Mototsugu
authors.initials: M
authors.lastname: Kato
authors.forename: Tomoo
authors.initials: T
authors.lastname: Itoh
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ota
authors.forename: Satoru
authors.initials: S
authors.lastname: Todo
mesh_terms: D018256:Adenomatous Polyps / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D003110:Colonic Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D003111:Colonic Polyps / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D003113:Colonoscopy; D017809:Fatal Outcome; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D007223:Infant