title: [Chemotherapy with combination of UFT and cisplatin against metastatic ovarian tumor originating from gastric cancer].
abstract: Krukenberg's tumor, an metastatic ovarian tumor originating from gastric cancer, is a disease with extremely poor prognosis, and it is rare for patients to survive for more than 2 years after the diagnosis. We encountered a patient in whom a long-term good prognosis could be obtained probably because of the effects of chemotherapy after the ovarian tumor extraction. This patient was treated by a combination of UFT and cisplatin. Enhancement of the antitumor effects by the concomitant use of 5-FU and cisplatin has been attracting attention, and the methods of administration of these drugs have been investigated by numerous researchers as FP therapy. It was characteristic to the treatment of our patient that 5-FU was administered in the form of oral UFT. We believe this was an important experience suggesting that this administration method is safe and effective, and even influences the long-term prognosis.
authors.affiliation: Dept. of Gynecology, Cancer Institute Hospital.
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Katase
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Shimizu
authors.forename: Yaeko
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Hasumi
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D018279:Carcinoma, Signet Ring Cell / Q000188:drug therapy* / Q000556:secondary*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004333:Drug Administration Routes; D005260:Female; D006801:Humans; D020883:Hysterotomy; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D010052:Ovariectomy; D011379:Prognosis; D013274:Stomach Neoplasms / Q000473:pathology*; D005641:Tegafur / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage
chemical_list: D005641:Tegafur; D014498:Uracil; D002945:Cisplatin