title: Antioxidant iridoid glucosides from Wendlandia formosana.
abstract: Two new iridoid glucosides of 10-O-caffeoyl scandoside methyl ester (3), and 6-methoxy scandoside methyl ester (4) besides the known compounds of scandoside methyl ester (1), methyl deacetyl asperulosidate (2), 10-O-caffeoyl daphylloside (5), phytol (6), and ursolic acid (7) were isolated from the leaves of Wendlandia formosana. Structure elucidation of the new iridoid glucosides was based on interpretation of high-resolution 1D and 2D NMR spectral data and chemical conversions. Antioxidant activity of Compounds (1-5) against diphenylpicrylhydrazyl (DPPH) and hydroxyl radical, and peroxynitrite was reported.
authors.affiliation: Department of Medicinal Chemistry, School of Pharmacy, Taipei Medical University, No. 250, Wu-Hsing Street, Taipei 110-31, Taiwan, ROC.
authors.forename: B Lakshmana
authors.initials: BL
authors.lastname: Raju
authors.forename: Shwu-Jiuan
authors.initials: SJ
authors.lastname: Lin
authors.forename: Wen-Chi
authors.initials: WC
authors.lastname: Hou
authors.forename: Zhi-Yang
authors.initials: ZY
authors.lastname: Lai
authors.forename: Pan-Chun
authors.initials: PC
authors.lastname: Liu
authors.forename: Feng-Lin
authors.initials: FL
authors.lastname: Hsu
mesh_terms: D000975:Antioxidants / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D001713:Biphenyl Compounds; D006801:Humans; D039823:Iridoids / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D008517:Phytotherapy; D010851:Picrates / Q000737:chemistry; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D019666:Rubiaceae
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D039823:Iridoids; D010851:Picrates; D010936:Plant Extracts; C004931:1,1-diphenyl-2-picrylhydrazyl