title: Tryptophan-derived sulfur-containing phytoalexins--a general overview.
abstract: Phytoalexins are low molecular weight antimicrobial compounds that are synthesized and accumulated in plants after their exposure to pathogenic microorganisms (bacteria, fungi, viruses and protozoans). They are extensively studied now as promising antifungal, potentially anticancer and plant diseases controlling agents. The article pertains to a group of indole-derived phytoalexins--brassinins, containing at least one sulfur atom in the side chain or in the ring(s), isolated from the cruciferous plants. Up today more than 20 compounds, closely related biogenetically, but exhibiting diversified biological activity have been identified. The survey summerises most promising recent results pertaining practical application of brassinins and camalexins.
authors.affiliation: Faculty of Chemistry, Warsaw University, L. Pasteur Str. 1, 02-093 Warsaw, Poland. ruszko@chem.uw.edu.pl
authors.forename: Joanna
authors.initials: J
authors.lastname: Ruszkowska
authors.forename: Jerzy T
authors.initials: JT
authors.lastname: Wróbel
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification; D007211:Indoles / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism; D010944:Plants / Q000378:metabolism; D012717:Sesquiterpenes; D013455:Sulfur / Q000737:chemistry; D013729:Terpenes; D013844:Thiazoles / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D013859:Thiocarbamates / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D014364:Tryptophan / Q000737:chemistry* / Q000378:metabolism; D000094162:Phytoalexins
chemical_list: D000890:Anti-Infective Agents; D007211:Indoles; D010936:Plant Extracts; D012717:Sesquiterpenes; D013729:Terpenes; D013844:Thiazoles; D013859:Thiocarbamates; C102405:camalexin; C089020:brassinin; D013455:Sulfur; D014364:Tryptophan; D000094162:Phytoalexins