title: Corrosion of tungsten coils after peripheral vascular embolization therapy: influence on outcome and tungsten load.
abstract: The purpose of this study was to evaluate coil corrosion and the long-term outcome after peripheral vascular embolization therapy performed with tungsten coils. We studied 14 patients who received tungsten coils on an average of 26 months prior to follow-up. The protocol included plain radiography and contrast-enhanced magnetic resonance angiography to investigate corrosion of tungsten coils and recanalization of the embolized vessels. Whole blood, hair, and urine tungsten levels were assayed when available. Corrosion of tungsten coils was detected in 9 of 14 patients by plain radiography. No evidence of recanalization of the embolized vessel and no adverse clinical effects of tungsten resorption were detected. Blood levels of tungsten were elevated in 6 of 14 patients and urine levels of tungsten were elevated in all 12 patients tested. Tungsten coil corrosion and elevated tungsten levels in blood, hair, and urine were found in most patients, although no adverse clinical effects of tungsten resorption were detected. Since the overall effect of high tungsten blood levels remains unclear, its use as an implant should be avoided.
authors.affiliation: Department of Diagnostic Radiology, University Hospital of Regensburg, Regensburg, Germany. bachtlaler@klinik.uni-regensburg.de
authors.forename: Maike
authors.initials: M
authors.lastname: Bachthaler
authors.forename: Markus
authors.initials: M
authors.lastname: Lenhart
authors.forename: Christian
authors.initials: C
authors.lastname: Paetzel
authors.forename: Stefan
authors.initials: S
authors.lastname: Feuerbach
authors.forename: Johann
authors.initials: J
authors.lastname: Link
authors.forename: Christoph
authors.initials: C
authors.lastname: Manke
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003343:Corrosion; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D004868:Equipment Failure; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000628:therapy*; D017973:Tungsten Compounds / Q000032:analysis*
chemical_list: D017973:Tungsten Compounds