Anticarcinogenic activity of Withania somnifera Dunal against Dalton's ascitic lymphoma.
The effect of ethanolic extract of the root of Withania somnifera Dunal (REWS) against Dalton's Ascitic Lymphoma has been evaluated in Swiss albino mice. A significant increase in the life span and a decrease in the cancer cell number and tumour weight were noted in the tumour-induced mice after treatment with REWS. The hematological parameters were also corrected by REWS in tumour-induced mice. These observations are suggestive of the protective effect of REWS in Dalton's Ascitic Lymphoma (DAL).
Christina
A J M
AJ
Division of Pharmacology, K.M. College of Pharmacy, Uthangudi, Melur Road, Madurai 625 107, Tamil Nadu, India. tinatina38@rediffmail.com
Joseph
D Gladwin
DG
Packialakshmi
M
M
Kothai
R
R
Robert
S Jerry Heison
SJ
Chidambaranathan
N
N
Ramasamy
M
M
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001201:Ascites / Q000188:drug therapy / Q000473:pathology; D008223:Lymphoma / Q000188:drug therapy / Q000473:pathology; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000188:drug therapy / Q000473:pathology; D010529:Peritoneal Cavity / Q000166:cytology; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018517:Plant Roots; D032341:Withania
D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts