title: Spatial coherence of backscatter for the nonlinearly produced second harmonic for specific transmit apodizations.
abstract: To be successful, correlation-based, phase-aberration correction requires a high correlation among backscattered signals. For harmonic imaging, the spatial coherence of backscatter for the second harmonic component is different than the spatial coherence of backscatter for the fundamental component. The purpose of this work was to determine the effect of changing the transmit apodization on the spatial coherence of backscatter for the nonlinearly generated second harmonic. Our approach was to determine the effective apodizations for the fundamental and second harmonic using both experimental measurements and simulations. Two-dimensional measurements of the transverse cross sections of the finite-amplitude ultrasonic fields generated by rectangular and circular apertures were acquired with a hydrophone. Three different one-dimensional transmit apodization functions were investigated: uniform, Riesz, and trapezoidal. An effective apodization was obtained for each transmit apodization by backpropagating the values measured from within the transmit focal zone using a linear angular spectrum approach. Predictions of the spatial coherence of backscatter were obtained using the pulse-echo Van Cittert-Zernike theorem. In all cases the effective apodization at 2f was narrower than the transmit apodization. We demonstrate that certain transmit apodizations result in a greater spatial coherence of backscatter at the second harmonic than at the fundamental.
authors.affiliation: Washington University, St. Louis, MO 63130, USA. rjfedewa@ece.rochester.edu
authors.forename: Russell J
authors.initials: RJ
authors.lastname: Fedewa
authors.forename: Kirk D
authors.initials: KD
authors.lastname: Wallace
authors.forename: Mark R
authors.initials: MR
authors.lastname: Holland
authors.forename: James R
authors.initials: JR
authors.lastname: Jago
authors.forename: Gary C
authors.initials: GC
authors.lastname: Ng
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Rielly
authors.forename: Brent S
authors.initials: BS
authors.lastname: Robinson
authors.forename: James G
authors.initials: JG
authors.lastname: Miller
mesh_terms: D000818:Animals; D016477:Artifacts; D003198:Computer Simulation; D003238:Connective Tissue / Q000000981:diagnostic imaging*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008954:Models, Biological; D017711:Nonlinear Dynamics; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012542:Scattering, Radiation; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D013223:Statistics as Topic; D014463:Ultrasonography / Q000295:instrumentation / Q000379:methods*