Botulinum toxin for the treatment of congenital entropion.
OBJECTIVE
To describe a case of congenital entropion presenting with ulcerative keratitis that was successfully treated with a single injection of botulinum toxin.


METHODS
Interventional case report.


METHODS
A 3-week-old female infant with a corneal ulcer of the left eye since birth presented for evaluation. She was found to have entropion of the left lower lid. The pretarsal orbicularis muscle was injected with 5 units of botulinum toxin.


RESULTS
Four days after treatment, the entropion had resolved and the corneal epithelial defect had healed. There was no recurrence of the entropion 7 months after botulinum toxin injection.


CONCLUSIONS
Injection of botulinum toxin can effectively treat certain cases of congenital entropion.
Christiansen
Gregory
G
Department of Ophthalmology, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, MN 55905, USA.
Mohney
Brian G
BG
Baratz
Keith H
KH
Bradley
Elizabeth A
EA
D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D003320:Corneal Ulcer / Q000188:drug therapy / Q000209:etiology; D004774:Entropion / Q000150:complications / Q000151:congenital* / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007273:Injections, Intramuscular; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D009801:Oculomotor Muscles / Q000187:drug effects
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A