title: Propofol for procedural sedation in the pediatric emergency department.
abstract: This retrospective case series reports our experience using propofol for procedural sedation in the Emergency Department over an 18-month period with 52 pediatric patients. Propofol sedation was performed successfully in all children (mean age, 10.2 years; range 0.7-17.4 years). Indications for sedation included orthopedic manipulation, incision and drainage of abscess, sexual assault examination, laceration repair, and non-invasive imaging studies. The mean dose administered with the intermittent bolus and continuous infusion methods of delivery was 4.25 mg/kg (+/- 1.86) and 8.3 mg/kg/h, respectively. The mean recovery time was 27.1 min (+/- 15.84). No patient required assisted ventilation or developed clinically significant hypotension. Respiratory depression requiring airway repositioning or supplemental oxygen was noted in 5.8% (3/52) patients. Propofol is a reasonable alternative to facilitate sedation for a range of procedures performed in a busy Pediatric Emergency Department.
authors.affiliation: Division of Critical Care & Emergency Services, Department of Pediatrics, LeBonheur Children's Medical Center, 50 N. Dunlap Street, Memphis, TN 38103, USA.
authors.forename: Jay
authors.initials: J
authors.lastname: Pershad
authors.forename: Sandip A
authors.initials: SA
authors.lastname: Godambe
mesh_terms: D000293:Adolescent; D000556:Ambulatory Surgical Procedures / Q000379:methods; D000698:Analgesia / Q000379:methods; D000701:Analgesics, Opioid / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D016292:Procedural Sedation / Q000379:methods* / Q000706:statistics & numerical data; D004635:Emergency Medicine / Q000379:methods*; D004636:Emergency Service, Hospital / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage* / Q000009:adverse effects; D000860:Hypoxia / Q000139:chemically induced; D007223:Infant; D008297:Male; D010043:Outcome and Process Assessment, Health Care; D010372:Pediatrics / Q000379:methods*; D011292:Premedication; D011300:Preoperative Care; D015742:Propofol / Q000008:administration & dosage* / Q000009:adverse effects; D012189:Retrospective Studies; D013714:Tennessee; D014947:Wounds and Injuries / Q000628:therapy
chemical_list: D000701:Analgesics, Opioid; D006993:Hypnotics and Sedatives; D015742:Propofol