title: [Juvenile gigantomastia. Case report and literature survey].
abstract: A juvenile gigantomastia with wet tender ulceration in a 13-year-old premenarchal girl (155 cm, 51 kg) developed in only 6 months. Treatment consisted of a bilateral reduction mammoplasty with free transplantation of the areolae and nipples and the removal of 4.2 kg of breast tissue. Macroscopically the resections consisted of "white and solid" tissue. Histologically a fibrous-cystic mastopathia was confirmed. It is thus suggested that the etiology of this disease might be related to a local hypersensitivity to estrogen. Mediactions (Tamoxifen) are mostly ineffective. The treatment consisted of reduction plasty.
authors.affiliation: I. Frauenklinik-Innenstadt der Ludwig-Maximilians-Universität München. bernd.gerber@fk-i.med.uni-muenchen.de
authors.forename: B
authors.initials: B
authors.lastname: Gerber
authors.forename: A
authors.initials: A
authors.lastname: Krause
authors.forename: E-M
authors.initials: EM
authors.lastname: Lochmüller
authors.forename: W
authors.initials: W
authors.lastname: Janni
authors.forename: K
authors.initials: K
authors.lastname: Friese
mesh_terms: D000293:Adolescent; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D006984:Hypertrophy; D016462:Mammaplasty / Q000379:methods; D016896:Treatment Outcome