title: EI-2346, a novel interleukin-1beta converting enzyme inhibitor produced by Streptomyces sp. E-2346. II. Structure elucidation.
authors.affiliation: Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., 3-6-6 Asahimachi, Machida-shi, Tokyo 194-8533, Japan. fumito.koizumi@kyowa.co.jp
authors.forename: Fumito
authors.initials: F
authors.lastname: Koizumi
authors.forename: Atsuhiro
authors.initials: A
authors.lastname: Hasegawa
authors.forename: Mayumi
authors.initials: M
authors.lastname: Yoshida
authors.forename: Yuzuru
authors.initials: Y
authors.lastname: Matsuda
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nakanishi
mesh_terms: D020170:Caspase 1 / Q000378:metabolism; D061945:Caspase Inhibitors; D004146:Dioxanes / Q000737:chemistry*; D004791:Enzyme Inhibitors / Q000737:chemistry*; D015394:Molecular Structure; D009285:Naphthoquinones / Q000737:chemistry* / Q000494:pharmacology; D019906:Nuclear Magnetic Resonance, Biomolecular; D011714:Pyrans / Q000737:chemistry*; D013302:Streptomyces / Q000737:chemistry*
chemical_list: D061945:Caspase Inhibitors; D004146:Dioxanes; C484082:EI-2346; D004791:Enzyme Inhibitors; D009285:Naphthoquinones; D011714:Pyrans; D020170:Caspase 1