Experimental determination of compound action potential direction and propagation velocity from multi-electrode nerve cuffs.
Information extracted from whole-nerve electroneurograms, recorded using electrode cuffs, can provide signals to neuroprostheses. However, the amount of information that can be extracted from a single tripole is limited. This communication demonstrates how previously unavailable information about the direction of action potential propagation and velocity can be obtained using a multi-electrode cuff and that the arrangement acts as a velocity-selective filter. Results from in vitro experiments on frog nerves are presented.
Rieger
R
R
Department of Electronic and Electrical Engineering, University College London, UK. robert.rieger@austriamicrosystems.com
Taylor
J
J
Comi
E
E
Donaldson
N
N
Russold
M
M
Mahony
C M O
CM
McLaughlin
J A
JA
McAdams
E
E
Demosthenous
A
A
Jarvis
J C
JC
D000200:Action Potentials / Q000502:physiology*; D000465:Algorithms; D000669:Amplifiers, Electronic; D000818:Animals; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004567:Electrodes, Implanted; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005240:Feasibility Studies; D008839:Microelectrodes; D009431:Neural Conduction / Q000502:physiology*; D011898:Ranidae; D012584:Sciatic Nerve / Q000502:physiology*