title: Frequency of silent myocardial ischemia in type 2 diabetic patients and the relation with poor glycemic control.
abstract: The aim of the study was to investigate the frequency of silent myocardial ischemia in type 2 diabetic patients without any clinical or laboratory findings of myocardial ischemia and to examine the related factors for silent myocardial ischemia. A total of 116 type 2 diabetic patients (82 women) with a disease duration of 5-20 years were included in the study. All patients underwent stress and resting myocardial perfusion single-photon emission computed tomographic (SPECT) study with (99m)Tc-MIBI. Coronary angiography was performed in patients with ischemia established at myocardial perfusion SPECT. Ischemia was determined in 18 (15.5%) patients by myocardial perfusion SPECT. Coronary angiography performed in 17 of these patients confirmed coronary stenosis >50% in 11 patients. Thus, the prevalence of silent myocardial ischemia was 9.6%. Significant relations were found between silent myocardial ischemia and male sex, high HbA(1C) level and retinopathy. Type 2 diabetic patients (especially men) with poorly controlled diabetes mellitus or retinopathy should be screened for silent myocardial ischemia.
authors.affiliation: Department of Internal Medicine, Medical Faculty, Gaziantep University, TR-27070, Gaziantep, Turkey. araz@gantep.edu.tr
authors.forename: M
authors.initials: M
authors.lastname: Araz
authors.forename: Z
authors.initials: Z
authors.lastname: Celen
authors.forename: I
authors.initials: I
authors.lastname: Akdemir
authors.forename: V
authors.initials: V
authors.lastname: Okan
mesh_terms: D000328:Adult; D000368:Aged; D001364:Awareness; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000503:physiopathology*; D003930:Diabetic Retinopathy / Q000453:epidemiology; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000453:epidemiology*; D012307:Risk Factors; D012907:Smoking
chemical_list: D008055:Lipids