Clopidogrel-associated autoimmune thrombocytopenic purpura.
We report the case of a 51-year-old male who underwent coronary stent placement for the treatment of an acute myocardial infarction. One week later, he developed symptomatic autoimmune thrombocytopenia likely related to clopidogrel use. This was successfully treated with intravenous methylprednisilone and platelet transfusions.
Best
Patricia J M
PJ
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Mayo Foundation, Rochester, Minnesota, USA.
Mathew
Verghese
V
Markovic
Svetomir N
SN
D000077144:Clopidogrel; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D009203:Myocardial Infarction / Q000628:therapy; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects*; D017713:Platelet Transfusion; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000139:chemically induced*; D015607:Stents; D013988:Ticlopidine / Q000009:adverse effects* / Q000031:analogs & derivatives*
D005938:Glucocorticoids; D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine; D008775:Methylprednisolone