title: [Prognostic values of oestradiol/oocyte rate in ICSI patients].
abstract: OBJECTIVE
  To analyze the pregnancy rate in women who underwent Intracytoplasmic Sperm Injection (ICSI) program depending of the oestradiol/oocyte index.
  
  
  METHODS
  Retrospective, comparative.
  
  
  METHODS
  332 patients were included. There were divided in three groups depending on the oestradiol/oocyte index: Group A:(100 pg/mL, group B: 101-250 pg/mL and group C: > 250 pg/mL). Therapeutic protocol. Down regulation with leuprolide acetate in late luteal phase protocol, COH with rec-FSH and / or HMG, ultrasonographic and estradiol blood levels were monitored; hCG application when > 3 follicles > 18 mm, oocyte retrieval performed 34 hours later. We analyzed: patient age, male age, number of follicles, estradiol serum levels at the day of hCG application, number of mature oocytes, oestradiol/oocyte index, fertilization rate, transferred embryos, transfer quality, catheter type and luteal support. Statistical analysis (SPSS 11) with chi square, ANOVA and Kruskall-Wallis was used.
  
  
  RESULTS
  On having analyzed the number of metaphase II oocytes retrieval, oocytes fertilized and number of transferred embryos among three groups, the best results were obtained in group B. The differences among these variables were significant. (P = 0.014, p = 0.005 and p = 0.003, respectively). When the oestradiol/oocyte index was analyzed and the PR among groups (21.83, 36.62 and 17.80 %) we observed a significant difference (p = 0.003).
  
  
  CONCLUSIONS
  It is convenient to monitor the oestradiol blood levels to offer schemes of COH less aggressive to improve the oocyte quality. The oestradiol/oocyte index is a parameter adapted as a predictive value of pregnancy.
authors.affiliation: Instituto para el Estudio de la Concepción Humana, Monterrey, NL.
authors.forename: Pedro
authors.initials: P
authors.lastname: Galache Vega
authors.forename: Eric
authors.initials: E
authors.lastname: Saucedo de la Llata
authors.forename: Armando
authors.initials: A
authors.lastname: Treviño Rodríguez
authors.forename: Roberto
authors.initials: R
authors.lastname: Santos Haliscak
authors.forename: Víctor Alfonso
authors.initials: VA
authors.lastname: Batiza Reséndiz
authors.forename: Lidia
authors.initials: L
authors.lastname: Arenas Montezco
authors.forename: María Rosa
authors.initials: MR
authors.lastname: Moraga Sánchez
authors.forename: José
authors.initials: J
authors.lastname: Sepúlveda González
authors.forename: Manuel
authors.initials: M
authors.lastname: Leal Almeida
authors.forename: Jorge
authors.initials: J
authors.lastname: Rodríguez Pezino
authors.forename: Genaro
authors.initials: G
authors.lastname: García Villafaña
authors.forename: Samuel
authors.initials: S
authors.lastname: Hernández Ayup
mesh_terms: D000328:Adult; D002452:Cell Count; D004958:Estradiol / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D010063:Ovum; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic
chemical_list: D004958:Estradiol