Selectively hydrogenated soybean oil with conjugated linoleic acid modifies body composition and plasma lipids in rats.
The present study examined effects of a selectively hydrogenated soybean oil (SHSO) containing about 21% CLA on body composition, adipose depots and organ weights, and plasma lipid profiles in rats. Male Sprague Dawley rats were fed for 6 weeks a purified diet containing 0%, 1%, 3%, and 5% of SHSO. Different levels of SHSO supplementation did not significantly affect growth performance, although there was a trend toward decreased body weight gain with increasing dietary SHSO levels. The weights of inguinal, epididymal, and retroperitoneal adipose depot, but not mesenteric, were significantly influenced by dietary SHSO supplementation (P < 0.05, P < 0.01 and P < 0.001, respectively). Although the absolute weight of body protein in the control rats was higher in SHSO-fed rats, the effect on absolute weight of body protein is diluted and eliminated when the data are adjusted for eviscerated carcass weight as a percentage base. Therefore, as dietary SHSO level increased, body protein as a percentage of carcass weight increased (P < 0.05), although as dietary SHSO level increased, body fat proportion in carcass decreased (P < 0.01). Plasma triglycerides (TG) and total cholesterol (TC) concentrations were beneficially decreased, and HDL-cholesterol (HDL-C) to TC ratio was also beneficially increased by SHSO supplementation (P < 0.05, P < 0.001, and P < 0.01, respectively). However, plasma HDL-C concentration undesirably decreased with dietary SHSO supplementation (P < 0.05). The present study observed that body composition and plasma lipids were beneficially modulated by SHSO supplementation at least 3% levels (0.6% of CLA), and suggested that SHSO is a useful fat source because of the high level of CLA.
Choi
Nag- Jin
N
Division of Life Sciences and Silver Biotechnology Research Center, Hallym University, Chunchon, Kangwon-do 200-702, South Korea.
Kwon
Daehyeon
D
Yun
Suk Hoo
SH
Jung
Mun Yhung
MY
Shin
Hyun-Kyung
HK
D000273:Adipose Tissue / Q000033:anatomy & histology / Q000187:drug effects; D000818:Animals; D001823:Body Composition / Q000187:drug effects*; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D004042:Dietary Fats, Unsaturated / Q000494:pharmacology*; D006865:Hydrogenation; D044243:Linoleic Acids, Conjugated / Q000008:administration & dosage / Q000032:analysis*; D008055:Lipids / Q000097:blood*; D008297:Male; D009929:Organ Size; D011506:Proteins / Q000032:analysis; D051381:Rats; D017207:Rats, Sprague-Dawley; D013024:Soybean Oil / Q000737:chemistry* / Q000494:pharmacology*; D014280:Triglycerides / Q000032:analysis
D008076:Cholesterol, HDL; D004042:Dietary Fats, Unsaturated; D044243:Linoleic Acids, Conjugated; D008055:Lipids; D011506:Proteins; D014280:Triglycerides; D013024:Soybean Oil; D002784:Cholesterol