title: Preliminary studies on Campomanesia xanthocarpa (Berg.) and Cuphea carthagenensis (Jacq.) J.F. Macbr. aqueous extract: weight control and biochemical parameters.
abstract: An infusion of Campomanesia xanthocarpa Berg. (Myrtaceae) leaves (Guabiroba) and the herb Cuphea carthagenensis (Jacq.) J.F. Macbr. (Lythraceae) (Sete-sangrias) is traditionally used in the South of Brazil to treat high levels of cholesterol and triglycerides. The effects of the aqueous extracts of these herbs were investigated in rats fed on a high calorie diet. Chronic treatment with the Guabiroba aqueous extract induced a significant reduction in weight gain in the rats, compared to the control group. Also, biochemical analysis showed that this treatment reduced the glycemia, while no effects on lipidic levels were observed. The biochemical analysis of the animals treated with Sete-sangrias aqueous extract showed no effect on glucose and triglyceride levels, while chronic treatment with the Sete-sangrias aqueous extract induced a significant reduction in plasma cholesterol in rats.
authors.affiliation: Núcleo de Investigações Químico-Farmacêuticas (Niqfar), Curso de Farmácia, CCS, University of Vale do Itajaí (UNIVALI), Rua: Uruguai 458, Itajaí, Santa Catarina (SC) 88302-202, Brazil. maique@ccs.univali.br
authors.forename: M W
authors.initials: MW
authors.lastname: Biavatti
authors.forename: C
authors.initials: C
authors.lastname: Farias
authors.forename: F
authors.initials: F
authors.lastname: Curtius
authors.forename: L M
authors.initials: LM
authors.lastname: Brasil
authors.forename: S
authors.initials: S
authors.lastname: Hort
authors.forename: L
authors.initials: L
authors.lastname: Schuster
authors.forename: S N
authors.initials: SN
authors.lastname: Leite
authors.forename: S R T
authors.initials: SR
authors.lastname: Prado
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000187:drug effects; D002784:Cholesterol / Q000097:blood; D031562:Cuphea; D000960:Hypolipidemic Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D027822:Myrtaceae; D009765:Obesity / Q000517:prevention & control; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D051381:Rats; D017208:Rats, Wistar; D014280:Triglycerides / Q000097:blood; D015431:Weight Loss
chemical_list: D001786:Blood Glucose; D000960:Hypolipidemic Agents; D010936:Plant Extracts; D014280:Triglycerides; D002784:Cholesterol