Development of a rubella vaccination strategy: contribution of a rubella susceptibility study of women of childbearing age in Kyrgyzstan, 2001.
To contribute to the development of a rubella vaccination strategy, we conducted a study to determine age-specific susceptibility among women aged 15-39 years by testing for rubella-specific IgG antibodies. Of 964 women, 13% were found to be susceptible to rubella. Significantly higher susceptibility among women >25 years old was observed. Susceptibility data are important but are not sufficient to develop a vaccination strategy. After considering all available information, we suggested vaccination of women aged <35 years and selective vaccination of older women who were planning pregnancy.
Malakmadze
Naile
N
Polio Eradication Branch, Global Immunization Division, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. nailemlk@yahoo.com
Zimmerman
Laura A
LA
Uzicanin
Amra
A
Shteinke
Luidmila
L
Caceres
Victor M
VM
Kasymbekova
Kaliya
K
Sozina
Irina
I
Glasser
John W
JW
Joldubaeva
Mira
M
Aidyralieva
Chinara
C
Icenogle
Joseph P
JP
Strebel
Peter M
PM
Reef
Susan E
SE
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D005260:Female; D006801:Humans; D007110:Immunity, Active; D007707:Kyrgyzstan; D012409:Rubella / Q000276:immunology* / Q000517:prevention & control*; D012411:Rubella Vaccine / Q000008:administration & dosage*; D012412:Rubella virus / Q000276:immunology; D014611:Vaccination / Q000592:standards
D000914:Antibodies, Viral; D012411:Rubella Vaccine