title: Intramolecular catalytic Friedel-Crafts reactions with allenyl cations for the synthesis of quinolines and their analogues.
abstract: [reaction: see text] This paper describes a novel method to synthesize a quinoline backbone by incorporating allenyl cations into a catalytic intramolecular Friedel-Crafts reaction. The initial products were isomerized and aromatized upon treatment with acid and base, respectively, to give quinolines. The basic concept also proved to be promising for 1-benzazepine, 1-benzazocine, or isoquinoline synthesis.
authors.affiliation: Department of Bioscience and Biotechnology, School of Engineering and School of Education, Okayama University, Tsushima, Okayama, Japan 700-8530.
authors.forename: Teruhiko
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Shinobu
authors.initials: S
authors.lastname: Manabe
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Aikawa
authors.forename: Takayuki
authors.initials: T
authors.lastname: Kudo
authors.forename: Seiki
authors.initials: S
authors.lastname: Saito