title: [A case report of extrahepatic hepatocellular carcinoma with lymphocytic infiltration].
abstract: Hepatocellular carcinoma (HCC) with lymphocytic infiltration is a rare entity recently described, sometimes associated with hepatitis C. Histologically, remarkable inflammatory cell infiltration of cancer nests is observed, mostly composed of T cytotoxic lymphocytes. When prominent, this inflammatory cell component can obscure the neoplastic cells, leading to diagnostic difficulty. Alike tumors showing dense lymphocytic infiltrate, it discloses a better prognosis than other HCC. We report a case of HCC with lymphocytic infiltration arising in the right suprarenal space, in a 45-year-old man with no chronic liver disease. The patient is alive without recurrence three years after surgical resection. This report is original because HCC growing ectopically are rare and need to be distinguished, specially in the right retroperitoneal, from metastatic adrenal HCC.
authors.affiliation: Laboratoire de Pathologie Cellulaire, Centre Hospitalo-Universitaire Albert Michallon, Grenoble.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Sturm
authors.forename: Philippe
authors.initials: P
authors.lastname: Chaffanjon
authors.forename: Dimitri
authors.initials: D
authors.lastname: Salameire
authors.forename: Jean Pierre
authors.initials: JP
authors.lastname: Zarski
authors.forename: Christian
authors.initials: C
authors.lastname: Letoublon
authors.forename: Christian
authors.initials: C
authors.lastname: Sengel
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Brambilla
mesh_terms: D000008:Abdominal Neoplasms / Q000276:immunology / Q000473:pathology* / Q000601:surgery; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000276:immunology / Q000473:pathology* / Q000601:surgery; D002828:Choristoma / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D008214:Lymphocytes / Q000473:pathology*; D008297:Male; D017154:Stromal Cells / Q000473:pathology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome