title: Concomitant coronary and multiple arch vessel stenoses in patients treated with external beam radiation: pathophysiological basis and endovascular treatment.
abstract: External beam radiation-induced stenoses isolated to the coronary arteries or peripheral vessels have been previously described. We report for the first time the clinical presentation of two patients with concomitant coronary artery and multiple arch vessel disease following external beam radiation of the chest. We review the pathophysiology, discuss the treatment options and describe the percutaneous treatment of coronary, carotid, subclavian, and axillary stenoses related to this rare but likely underdiagnosed disorder.
authors.affiliation: Division of Cardiology, University of California, San Diego, California, USA.
authors.forename: Jeffrey J
authors.initials: JJ
authors.lastname: Cavendish
authors.forename: Brett J
authors.initials: BJ
authors.lastname: Berman
authors.forename: Guido
authors.initials: G
authors.lastname: Schnyder
authors.forename: Charles
authors.initials: C
authors.lastname: Kerber
authors.forename: Ehtisham
authors.initials: E
authors.lastname: Mahmud
authors.forename: Zoltan G
authors.initials: ZG
authors.lastname: Turi
authors.forename: Daniel
authors.initials: D
authors.lastname: Blanchard
authors.forename: Sotirios
authors.initials: S
authors.lastname: Tsimikas
mesh_terms: D000368:Aged; D000792:Angiography; D001918:Brachytherapy / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000532:radiotherapy*; D002339:Carotid Arteries / Q000528:radiation effects*; D016893:Carotid Stenosis / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D023921:Coronary Stenosis / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D003331:Coronary Vessels / Q000293:injuries / Q000528:radiation effects*; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000532:radiotherapy*; D008875:Middle Aged