Neuroimaging of Parkinson's disease and atypical parkinsonism.
The basal ganglia and its associated circuitry can be assessed with a variety of neuroimaging methods that can provide information regarding specific neurotransmitter systems, the functional activity of brain regions, and the structural integrity of these regions. In Parkinson's disease (PD) and related atypical parkinsonian syndromes (APS), these imaging methods may be useful for many reasons, including aiding in differential diagnosis and measuring the efficacy of new therapies. This paper reviews recent developments in the application of neuroimaging to the assessment of PD and related APS.
Zgaljardic
Dennis J
DJ
Center for Neurosciences, North Shore-Long Island Jewish Research Institute, 350 Community Drive, Manhasset, NY 11030, USA. dzgaljar@nshs.edu
Feigin
Andrew
A
D000818:Animals; D001479:Basal Ganglia / Q000378:metabolism / Q000473:pathology; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D010300:Parkinson Disease / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy; D020734:Parkinsonian Disorders / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy