title: Successful treatment of methicillin-resistant Staphylococcus aureus endocarditis with linezolid.
abstract: We report the successful treatment with linezolid of a methicillin-resistant Staphylococcus aureus (MRSA) endocarditis in a patient with a severe allergic reaction to glycopeptides. Linezolid is a drug with well-recognised activity against S. aureus and proved to be efficacious even in the unusual site of heart valves. This drug could be a good therapeutic choice when glycopeptides treatment is not feasible.
authors.affiliation: Department of Infectious Diseases, San Martino Hospital, University of Genoa, School of Medicine, Genoa, Italy.
authors.forename: Matteo
authors.initials: M
authors.lastname: Bassetti
authors.forename: Antonio
authors.initials: A
authors.lastname: Di Biagio
authors.forename: Valerio
authors.initials: V
authors.lastname: Del Bono
authors.forename: Giovanni
authors.initials: G
authors.lastname: Cenderello
authors.forename: Dante
authors.initials: D
authors.lastname: Bassetti
mesh_terms: D000081:Acetamides / Q000627:therapeutic use*; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D004697:Endocarditis, Bacterial / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D000069349:Linezolid; D016106:Methicillin Resistance; D023303:Oxazolidinones / Q000627:therapeutic use*; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000081:Acetamides; D000890:Anti-Infective Agents; D023303:Oxazolidinones; D000069349:Linezolid