title: Multipoint recognition of basic proteins at a membrane model.
abstract: Cell surface recognition achieves high efficiency and specificity because of its polyvalent nature. A biomimetic model has been designed, which consists of a stearic acid monolayer with embedded calixarene tetraphosphonate receptor molecules. This system is able to distinguish between proteins of varying pI at nanomolar concentrations.
authors.affiliation: Fachbereich Chemie, Philipps-Universität Marburg, Hans-Meerwein-Strasse, 35032 Marburg, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Zadmard
authors.forename: M
authors.initials: M
authors.lastname: Arendt
authors.forename: T
authors.initials: T
authors.lastname: Schrader
mesh_terms: D047250:Calixarenes; D050356:Lipid Metabolism; D008055:Lipids / Q000737:chemistry; D008565:Membrane Proteins / Q000737:chemistry* / Q000378:metabolism; D008958:Models, Molecular; D011083:Polycyclic Compounds / Q000737:chemistry*; D013229:Stearic Acids / Q000737:chemistry; D013499:Surface Properties
chemical_list: D008055:Lipids; D008565:Membrane Proteins; D011083:Polycyclic Compounds; D013229:Stearic Acids; D047250:Calixarenes