Analysis of survival data with cross-effects of survival functions.
We present a model and semiparametric estimation procedures for analysis of survival data with cross-effects (CE) of survival functions. Finite sample properties of the estimators are analyzed by simulation. A goodness-of-fit test for the proportional hazards model against the CE model is proposed. The well known data concerning effects of chemotherapy and radiotherapy on the survival times of gastric cancer patients is analyzed as an example.
Bagdonavicius
Vilijandas
V
Department of Mathematical Statistics, University of Vilnius, Naugarduko 24, Vilnius, Lithuania.
Hafdi
Mohamed A
MA
Nikulin
Mikhail
M
D002986:Clinical Trials as Topic / Q000379:methods; D003627:Data Interpretation, Statistical; D005770:Gastrointestinal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D006801:Humans; D015233:Models, Statistical; D016019:Survival Analysis