title: Towards clinical bioinformatics: advancing genomic medicine with informatics methods and tools.
abstract: OBJECTIVE
  To summarize the challenges facing clinical applications in the light of growing research results in genomic medicine and bioinformatics.
  
  
  METHODS
  Analysis of the contents of the Yearbook of Medical Informatics 2004 of the International Medical Informatics Association (IMIA).
  
  
  RESULTS
  The Yearbook of Medical Informatics 2004 includes 32 articles selected from 22 peer-reviewed scientific journals. A special section on clinical bioinformatics highlights recent developments in this field. Several guest editors review the promises and limitations of available methods and resources from biomedical informatics that are relevant to clinical medicine. Integrated data and knowledge resources are generally regarded to be central and key issues for clinical bioinformatics. Further review papers deal with public health implications of bioinformatics, knowledge management and trends in health care education. The Yearbook includes for the first time a section on the history of medical informatics, where the significant impact of the Reisensburg protocol 1973 on international health and medical informatics education is examined.
  
  
  CONCLUSIONS
  Close collaboration between bioinformatics and medical informatics researchers can contribute to new insights in genomic medicine and contribute towards the more efficient and effective use of genomic data to advance clinical care.
authors.affiliation: University of Heidelberg, Department of Medical Informatics, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany. petra_knaup@med.uni-heidelberg.de
authors.forename: P
authors.initials: P
authors.lastname: Knaup
authors.forename: E
authors.initials: E
authors.lastname: Ammenwerth
authors.forename: R
authors.initials: R
authors.lastname: Brandner
authors.forename: B
authors.initials: B
authors.lastname: Brigl
authors.forename: G
authors.initials: G
authors.lastname: Fischer
authors.forename: S
authors.initials: S
authors.lastname: Garde
authors.forename: E
authors.initials: E
authors.lastname: Lang
authors.forename: R
authors.initials: R
authors.lastname: Pilgram
authors.forename: F
authors.initials: F
authors.lastname: Ruderich
authors.forename: R
authors.initials: R
authors.lastname: Singer
authors.forename: A C
authors.initials: AC
authors.lastname: Wolff
authors.forename: R
authors.initials: R
authors.lastname: Haux
authors.forename: C
authors.initials: C
authors.lastname: Kulikowski
mesh_terms: D019295:Computational Biology / Q000639:trends; D023281:Genomics / Q000639:trends; D006801:Humans; D007390:International Agencies; D008490:Medical Informatics / Q000639:trends; D011643:Publishing; D012014:Reference Books, Medical; D012106:Research / Q000639:trends; D012952:Societies