Transjugular intrahepatic portosystemic shunt for palliative treatment of portal hypertension secondary to portal vein tumor thrombosis.
OBJECTIVE
To evaluate the palliative therapeutic effects of transjugular intrahepatic portosystemic shunt (TIPS) in portal vein tumor thrombosis (PVTT) complicated by portal hypertension.


METHODS
We performed TIPS for 14 patients with PVTT due to hepatocellular carcinoma (HCC). Of the 14 patients, 8 patients had complete occlusion of the main portal vein, 6 patients had incomplete thrombosis, and 5 patients had portal vein cavernous transformation. Clinical characteristics and average survival time of 14 patients were analysed. Portal vein pressure, ascites, diarrhoea, and variceal bleeding and circumference of abdomen were assessed before and after TIPS.


RESULTS
TIPS was successful in 10 cases, and the successful rate was about 71%. The mean portal vein pressure was reduced from 37.2 mmHg to 18.2 mmHg. After TIPS, the ascites decreased, hemorrhage stopped and the clinical symptoms disappeared in the 10 cases. The average survival time was 132.3 d. The procedure failed in 4 cases because of cavernous transformation in portal vein and severe cirrhosis.


CONCLUSIONS
TIPS is an effective palliative treatment to control hemorrhage and ascites due to HCC complicated by PVTT.
Jiang
Zai-Bo
ZB
3rd Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China. jzb01@163.net
Shan
Hong
H
Shen
Xin-Ying
XY
Huang
Ming-Sheng
MS
Li
Zheng-Ran
ZR
Zhu
Kang-Shun
KS
Guan
Shou-Hai
SH
D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000150:complications*; D005260:Female; D006801:Humans; D006975:Hypertension, Portal / Q000209:etiology / Q000601:surgery*; D008113:Liver Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009360:Neoplastic Cells, Circulating; D010166:Palliative Care; D011169:Portal Vein; D019168:Portasystemic Shunt, Transjugular Intrahepatic; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000209:etiology / Q000601:surgery*