title: Effectiveness of sirolimus-Eluting stent implantation for coronary narrowings <50% in diameter.
abstract: The long-term efficacy of percutaneous coronary intervention for mildly obstructive coronary narrowings is limited by the occurrence of restenosis, limiting the applicability of this therapy for these lesions. The present study reports on a consecutive series of 20 patients treated with sirolimus-eluting stent implantation for 23 angiographically mild de novo lesions (defined as a diameter stenosis <50% by quantitative coronary angiography). At a mean follow-up of 399 +/- 120 days, the survival-free of major adverse events was 95%, with no patient requiring target lesion revascularization.
authors.affiliation: Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands.
authors.forename: Angela
authors.initials: A
authors.lastname: Hoye
authors.forename: Pedro A
authors.initials: PA
authors.lastname: Lemos
authors.forename: Chourmouzios A
authors.initials: CA
authors.lastname: Arampatzis
authors.forename: Francesco
authors.initials: F
authors.lastname: Saia
authors.forename: Kengo
authors.initials: K
authors.lastname: Tanabe
authors.forename: Muzaffer
authors.initials: M
authors.lastname: Degertekin
authors.forename: Joost
authors.initials: J
authors.lastname: Daemen
authors.forename: Pieter C
authors.initials: PC
authors.lastname: Smits
authors.forename: Eugene
authors.initials: E
authors.lastname: McFadden
authors.forename: Sjoerd H
authors.initials: SH
authors.lastname: Hofma
authors.forename: Georgios
authors.initials: G
authors.lastname: Sianos
authors.forename: Pim
authors.initials: P
authors.lastname: de Feyter
authors.forename: Willem J
authors.initials: WJ
authors.lastname: Giessen
authors.forename: Ron T
authors.initials: RT
authors.lastname: van Domburg
authors.forename: Patrick W
authors.initials: PW
authors.lastname: Serruys
mesh_terms: D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D020123:Sirolimus / Q000008:administration & dosage*; D015607:Stents; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D020123:Sirolimus