Prediction of successful menorrhagia treatment after thermal balloon endometrial ablation.
BACKGROUND
Thermal balloon endometrial ablation (TBEA) is a non-hysteroscopic technique, which relies on a combination of heat and pressure within the uterine cavity to destroy endometrium and superficial myometrium. It is a simple, easy and minimally invasive procedure with an equivalent effectiveness to hysteroscopic endometrial ablation.


OBJECTIVE
To evaluate the effectiveness of TBEA in the treatment of menorrhagia and to identify the possible predictive factors for a successful outcome after 2-year follow-up.


METHODS
A prospective study was conducted, including 45 patients suffering from serious menorrhagia. Under local anesthesia with i.v. sedation, the Therma-Choice trade mark (Gynecare, Somerville, NJ, USA) balloon was inserted transcervically and after inflation in the endometrial cavity with 5% dextrose, it was heated to 87 degrees C for an 8-minute treatment cycle.


RESULTS
There were no intraoperative complications and postoperative morbidity was minimal. At 2-year follow-up the overall improvement of menstrual pattern was 85%; with reported 29% amenorrhea, 23.5% hypomenorrhea and 32.5% euomenorrhea. Menorrhagia persisted in 15% of patients. Multiple logistic regression analysis of the factors that could affect the outcome showed that the chance for a successful treatment increased significantly with increased age (P = 0.044), shorter uterine depth (P = 0.049) and adequate balloon pressure (P = 0.027). These were the predictive factors for successful outcome. However, parity, uterine volume and endometrial thickness were not predictive factors.


CONCLUSIONS
At 2-year follow-up, thermal balloon endometrial ablation is effective in menorrhagia treatment. Increased age, shorter uterine depth and adequate balloon pressure can be predictive factors for successful treatment.
Shaamash
Ayman H
AH
Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt. shamaashayman@yahoo.com
Sayed
Ezzat H
EH
D000328:Adult; D017115:Catheter Ablation / Q000379:methods*; D002404:Catheterization / Q000379:methods*; D004717:Endometrium / Q000601:surgery*; D005260:Female; D006358:Hot Temperature; D006801:Humans; D008595:Menorrhagia / Q000473:pathology / Q000628:therapy*; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D011312:Pressure; D011446:Prospective Studies; D016896:Treatment Outcome