title: Computed tomography demonstration of lipomatous metaplasia of the left ventricle following myocardial infarction.
abstract: Replacement of myocardium by fat, particularly of the right ventricle, is often diagnosed as arrhythmogenic right ventricular dysplasia. At autopsy, however, 68% of scars associated with chronic ischemic heart disease have shown fatty metaplasia in the scar. Four patients with a past history of previous myocardial infarctions and computed tomography demonstration of fatty change in left ventricular regions of hypokinesis and infarction are presented. It is proposed that these findings represent ischemic fatty metaplasia, an alternative etiology of fatty tissue replacing myocardium.
authors.affiliation: Department of Radiology, Indiana University School of Medicine, Indianapolis, IN, USA. hwinermu@iupui.edu
authors.forename: Helen T
authors.initials: HT
authors.lastname: Winer-Muram
authors.forename: Mark
authors.initials: M
authors.lastname: Tann
authors.forename: Alex M
authors.initials: AM
authors.lastname: Aisen
authors.forename: Lincoln
authors.initials: L
authors.lastname: Ford
authors.forename: S Gregory
authors.initials: SG
authors.lastname: Jennings
authors.forename: Robert
authors.initials: R
authors.lastname: Bretz
mesh_terms: D000273:Adipose Tissue / Q000000981:diagnostic imaging* / Q000473:pathology; D000368:Aged; D000369:Aged, 80 and over; D004452:Echocardiography; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008297:Male; D008679:Metaplasia; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications* / Q000473:pathology; D017202:Myocardial Ischemia / Q000473:pathology; D009206:Myocardium / Q000473:pathology*; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed / Q000379:methods*; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging