title: Potentiation of ischemia-related behavioral alterations by electro-acupuncture in gerbils.
abstract: Gerbils subjected to global ischemia or sham-ischemia received electro-acupuncture (EA) or sham EA at points 26 Du (Renzhong) and 8 Du (Junsuo). All animals were then tested for motor activity in an open field, and for spontaneous alternation in a T maze. Results show that EA alone did not affect any behavioral parameter. Ischemia alone increased motor activity without significantly interfering with spontaneous alternation. EA in ischemic gerbils potentiated the increase of motor activity and elicited a decrease in spontaneous alternation. Thus, our data show an interaction between global ischemia and EA applied at specific acupoints which, however, consists of a potentiation rather than an alleviation of the behavioral alterations consecutive to the ischemic insult.
authors.affiliation: IRCCS S. Lucia Foundation, Rome, Italy. l.restivo@hsantalucia.it
authors.forename: Leonardo
authors.initials: L
authors.lastname: Restivo
authors.forename: Silvia
authors.initials: S
authors.lastname: Middei
authors.forename: Luo
authors.initials: L
authors.lastname: Mingfu
authors.forename: Rosaria
authors.initials: R
authors.lastname: Reggio
authors.forename: Enrica
authors.initials: E
authors.lastname: Passino
authors.forename: Rita
authors.initials: R
authors.lastname: Formisano
authors.forename: Martine
authors.initials: M
authors.lastname: Ammassari-Teule
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D004195:Disease Models, Animal; D015671:Electroacupuncture; D005849:Gerbillinae; D002546:Ischemic Attack, Transient / Q000503:physiopathology* / Q000628:therapy*; D008297:Male; D018782:Maze Learning; D009043:Motor Activity; D013037:Spatial Behavior