title: Optical fiber-based biosensors.
abstract: This review outlines optical fiber-based biosensor research from January 2001 through September 2003 and was written to complement the previous review in this journal by Marazuela and Moreno-Bondi. Optical fiber-based biosensors combine the use of a biological recognition element with an optical fiber or optical fiber bundle. They are classified by the nature of the biological recognition element used for sensing: enzyme, antibody/antigen (immunoassay), nucleic acid, whole cell, and biomimetic, and may be used for a variety of analytes ranging from metals and chemicals to physiological materials.
authors.affiliation: Department of Chemistry, Pearson Lab, Tufts University, 62 Talbot Ave., Medford, MA 02155, USA. david.monk@tufts.edu
authors.forename: David J
authors.initials: DJ
authors.lastname: Monk
authors.forename: David R
authors.initials: DR
authors.lastname: Walt
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D004798:Enzymes / Q000737:chemistry; D004926:Escherichia coli / Q000737:chemistry; D005336:Fiber Optic Technology; D007118:Immunoassay; D009696:Nucleic Acids / Q000737:chemistry; D055100:Optical Fibers; D012680:Sensitivity and Specificity; D013499:Surface Properties; D013997:Time Factors
chemical_list: D004798:Enzymes; D009696:Nucleic Acids