Drug-induced lupus erythematosus.
Among the numerous idiopathic immune-mediated diseases that can be drug-induced, such as pemphigus, psoriasis, lichen, etc, drug-induced lupus is the most widely commented upon and investigated. The terms drug-induced lupus (DIL) and drug-induced lupus erythematosus (DILE) are preferred, but other ones are also used--drug-related lupus, lupus-like syndrome, and lupus erythematosus medicamentosus. This review discusses the general issues in DILE, such as pathogenic mechanisms, clinical forms, and diagnostic criteria, and provides more detailed information for some of the implicated drugs: minocycline, statins, terbinafine, etc.
Antonov
Dimitar
D
Department of Dermatology and Venereology, Sofia Faculty of Medicine, Sofia, Bulgaria. dimitar_antonov@doctor.bg
Kazandjieva
Jana
J
Etugov
Doncho
D
Gospodinov
Dimitar
D
Tsankov
Nikolai
N
D003875:Drug Eruptions / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000139:chemically induced / Q000175:diagnosis*