[Stents without restenosis--true or a myth?].
Routine stent implantations have significantly improved the results of percutaneous coronary angioplasty. In relation to balloon dilatation, the intervention success is improved, while restenosis as well as recurrence of progressive atherosclerotic disease at the site of previous dilatation are significantly reduced. In complicated interventional procedures such as dilatation of multi-vessels, long lesions, left main lesion, bifurcation lesions, dilatation of small vessels, and lesions in patients with diabetes mellitus in spite of stent implantation, the incidence of restenosis remains high, about 30%-50%. The introduction of drug-eluting stents (DES) such as sirolimus, paclitaxel and dexamethasone in interventional cardiology has brought important improvement with a significantly decreasing incidence of in-stent restenosis. Despite great enthusiasm and very good initial results, it should not be forgotten that the usage of these stents is still experimental, with many questions, especially concerning longterm results and use of DES in complicated interventional procedures.
Starcević
Boris
B
Zavod za bolesti srca i krvnih zila, Interna klinika Medicinskog fakulteta u Zagrebu, Klinicka bolnica Dubrava, Avenija Gojka Suska 6 10000 Zagreb, Hrvatska.
Vagić
Jozica Sikić
JS
D015906:Angioplasty, Balloon, Coronary; D003327:Coronary Disease / Q000628:therapy*; D023903:Coronary Restenosis / Q000517:prevention & control*; D006801:Humans; D017239:Paclitaxel / Q000008:administration & dosage; D020123:Sirolimus / Q000008:administration & dosage; D015607:Stents
D017239:Paclitaxel; D020123:Sirolimus