title: [Sclerotherapy with OK-432 for cystic tumors in the neck region].
abstract: BACKGROUND
  The intralesional injection of OK-432 has been proposed as an effective treatment of lymphangiomas and ranulas. The aim of this study was to review our experience with sclerotherapy of benign cervical cysts as an alternative method to surgical extirpation.
  
  
  METHODS
  We performed a case note review of six patients who received OK-432 injections in a concentration of 0.01 mg/ml between March 2002 and December 2003.
  
  
  RESULTS
  Disappearance of the lesions was achieved after one to three injections in all patients. We found a complete remission in two of six patients and a marked reduction in four of six patients. There were no significant complications observed.
  
  
  CONCLUSIONS
  OK-432 is an effective alternative in the treatment of benign cervical cysts, but it is very important to exclude malignancy-associated diseases before instillation of OK-432. Long-term results will be awaited.
authors.affiliation: Klinik für Hals-, Nasen-, Ohrenheilkunde, Kopf- und Halschirurgie, Martin Luther Universität Halle-Wittenberg, Halle. marc.bloching@medizin.uni-halle.de
authors.forename: M
authors.initials: M
authors.lastname: Bloching
authors.forename: G
authors.initials: G
authors.lastname: Götze
authors.forename: M
authors.initials: M
authors.lastname: Passmann
authors.forename: K
authors.initials: K
authors.lastname: Neumann
mesh_terms: D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D003560:Cysts; D005260:Female; D006258:Head and Neck Neoplasms / Q000628:therapy*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D010844:Picibanil / Q000008:administration & dosage*; D015911:Sclerotherapy / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D010844:Picibanil