title: Acute Korsakoff syndrome following mammillothalamic tract infarction.
abstract: There are limited case reports of structural lesions causing Korsakoff syndrome. This report describes acute Korsakoff syndrome following localized, bilateral infarction of the mammillothalamic tracts (MTTs). Axial T2-weighted imaging revealed the lesions at the lateral wall level of the third ventricle and diffusion-weighted imaging confirmed that the left lesion was new and the right old. Korsakoff syndrome persisted 6 months after the onset. This case suggests that bilateral MTT dysfunction can lead to Korsakoff syndrome.
authors.affiliation: Department of Neurosurgery, Yamagata Prefecture Central Hospital, Yamagata, Japan.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Yoneoka
authors.forename: Norio
authors.initials: N
authors.lastname: Takeda
authors.forename: Akira
authors.initials: A
authors.lastname: Inoue
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Ibuchi
authors.forename: Takashi
authors.initials: T
authors.lastname: Kumagai
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Sugai
authors.forename: Ken-ichiro
authors.initials: K
authors.lastname: Takeda
authors.forename: Kaoru
authors.initials: K
authors.lastname: Ueda
mesh_terms: D000208:Acute Disease; D020520:Brain Infarction / Q000150:complications* / Q000473:pathology; D006801:Humans; D020915:Korsakoff Syndrome / Q000209:etiology* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008326:Mammillary Bodies / Q000098:blood supply* / Q000473:pathology; D008875:Middle Aged