[Intravenous blood laser irradiation in patients with chronic nonspecific lung diseases and bronchial epithelial dysplasia].
The study included patients with chronic nonspecific lung diseases (CNLD) and a morphologically verified diagnosis of first-second degree bronchial epithelial dysplasia (BED). Forty-six patients underwent intravenous blood laser irradiation (IBLI) (a study group); 45 patients received routine anti-inflammatory therapy (a control group). After therapy in the study group, the clinical and endoscopic signs of an inflammatory process were eliminated in 80.4 and 78.2% of cases, respectively. With morphological monitoring, a full and partial regression of BED occurred in 63.1 and 17.4%, respectively. In the control group, clinical and endoscopic improvements were achieved in 53.3 and 52.0% of cases. Dysplastic changes could be arrested only in 8.9% of cases. The differences were statistically significant (p < 0.05). Thus, IBLI is a highly effective treatment of dysplastic bronchial epithelial changes in patients with CNLD as compared with the controls.
Cheremisina
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Pankova
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D000328:Adult; D001769:Blood / Q000528:radiation effects*; D001984:Bronchial Neoplasms / Q000473:pathology* / Q000601:surgery*; D002908:Chronic Disease; D004848:Epithelium / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D028022:Low-Level Light Therapy / Q000295:instrumentation*; D008171:Lung Diseases / Q000473:pathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000473:pathology* / Q000601:surgery*; D020545:Respiratory Mucosa / Q000473:pathology* / Q000601:surgery*; D014680:Veins