title: Concomitant keratoconus and macular corneal dystrophy.
abstract: OBJECTIVE
  To report the concomitant presentation of keratoconus and macular corneal dystrophy in two cases.
  
  
  METHODS
  Two siblings with concomitant keratoconus and macular corneal dystrophy are presented. Complete ophthalmologic examination and computerized videokeratography were performed in both patients. Case 1 underwent penetrating keratoplasty in both eyes sequentially; histopathologic examination of excised corneal buttons with special stains was performed. Case 2 was observed.
  
  
  RESULTS
  Both patients manifested typical signs and topographic evidence of keratoconus associated with macular dystrophy. Histopathologic studies in case 1 confirmed the same clinical diagnosis.
  
  
  CONCLUSIONS
  To our knowledge, this is the first report of such a concurrence in the English literature and could lead to further studies on the possible pathophysiologic or genetic link between these 2 entities.
authors.affiliation: Department of Ophthalmology, Tehran University of Medical Sciences, Tehran, Iran. ma-javadi@yahoo.com
authors.forename: Mohammad-Ali
authors.initials: MA
authors.lastname: Javadi
authors.forename: Alireza Baradaran
authors.initials: AB
authors.lastname: Rafee'i
authors.forename: Nasser
authors.initials: N
authors.lastname: Kamalian
authors.forename: Farid
authors.initials: F
authors.lastname: Karimian
authors.forename: Mohammad-Reza
authors.initials: MR
authors.lastname: Ja'farinasab
authors.forename: Shahin
authors.initials: S
authors.lastname: Yazdani
mesh_terms: D000293:Adolescent; D002648:Child; D003315:Cornea / Q000473:pathology; D003317:Corneal Dystrophies, Hereditary / Q000150:complications* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D019781:Corneal Topography; D006801:Humans; D007640:Keratoconus / Q000150:complications* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D015948:Keratoplasty, Penetrating; D008297:Male