title: Fatal ethibloc embolization of vertebrobasilar system following percutaneous injection into aneurysmal bone cyst of the second cervical vertebra.
abstract: A 4-year-old boy developed progressive neck pain and an expansile osteogenic lesion of C2; the diagnosis was an aneurysmal bone cyst. An image-guided biopsy with 3D CT planning was performed followed by Ethibloc injection into the aneurysmal bone cyst. Subsequent CT and MR images demonstrated embolization material in the vertebrobasilar system, and the patient died of brain stem and cerebellar infarction 23 hours after the intervention. The course of events and technical considerations are discussed.
authors.affiliation: Division of Neurosurgery, Hospital for Sick Children, Toronto, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Peraud
authors.forename: J M
authors.initials: JM
authors.lastname: Drake
authors.forename: D
authors.initials: D
authors.lastname: Armstrong
authors.forename: D
authors.initials: D
authors.lastname: Hedden
authors.forename: P
authors.initials: P
authors.lastname: Babyn
authors.forename: G
authors.initials: G
authors.lastname: Wilson
mesh_terms: D001488:Basilar Artery; D017824:Bone Cysts, Aneurysmal / Q000188:drug therapy*; D020520:Brain Infarction / Q000139:chemically induced*; D002574:Cervical Vertebrae; D002675:Child, Preschool; D003973:Diatrizoate / Q000009:adverse effects*; D004338:Drug Combinations; D004617:Embolism / Q000139:chemically induced*; D004621:Embolization, Therapeutic / Q000009:adverse effects*; D017809:Fatal Outcome; D005227:Fatty Acids / Q000009:adverse effects*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D011409:Propylene Glycols / Q000009:adverse effects*; D012597:Sclerosing Solutions / Q000009:adverse effects*; D013122:Spinal Diseases / Q000188:drug therapy*; D014711:Vertebral Artery; D015028:Zein / Q000009:adverse effects*
chemical_list: D004338:Drug Combinations; D005227:Fatty Acids; D011409:Propylene Glycols; D012597:Sclerosing Solutions; D003973:Diatrizoate; D015028:Zein; C020481:alcoholic prolamine solution