title: Spondylodiscitis after bilateral sequential lung transplantation in a patient with cystic fibrosis.
abstract: We report the case of a 24-year-old woman with cystic fibrosis in whom spondylodiscitis developed after bilateral sequential transplantation. The diagnostic work-up included magnetic resonance imaging, computed tomography-guided disk biopsy, histological examination, and cultures of disk specimens. The infective organism was D group Streptococcus and the patient was successfully treated with intravenous piperacillin followed by oral ampicillin. To our knowledge, this is the first reported case of spondylodiscitis after lung transplantation.
authors.affiliation: Cystic Fibrosis Center, Department of Pediatrics, University of Rome La Sapienza, Viale Regina Elena 324, 00161 Rome, Italy. serena.quattrucci@uniroma1.it
authors.forename: S
authors.initials: S
authors.lastname: Quattrucci
authors.forename: P
authors.initials: P
authors.lastname: Canuzzi
authors.forename: S
authors.initials: S
authors.lastname: Bertasi
authors.forename: A D
authors.initials: AD
authors.lastname: Grzejdziak
authors.forename: F
authors.initials: F
authors.lastname: Midulla
authors.forename: G
authors.initials: G
authors.lastname: Crucitti
authors.forename: E
authors.initials: E
authors.lastname: Melis
mesh_terms: D000328:Adult; D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003550:Cystic Fibrosis / Q000382:microbiology; D015299:Discitis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D016040:Lung Transplantation / Q000009:adverse effects*; D010878:Piperacillin / Q000627:therapeutic use; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013291:Streptococcus / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000667:Ampicillin; D010878:Piperacillin