[Advances on the immunotoxicity of airborne fine particulate matter (PM2.5)].
Exposure to airborne fine particulate matter (PM2.5) is an health risk factor, and immune system is one of the target tissues. Fine particulate matter had an effect on the host specific immune and nonspecific immune. The immune effect has two side, it can cause the damage to body, on the other hand it can also clean up the particulate matter. Immunotoxicity of PM2.5 is also associated with the other biological effect such as genotoxicity. Damage of fine particulate is through oxidant stress, inflammation and neurogenic inflammation and so on, but the detail of the mechanism for them is lacking. This review describes the immunotoxicity of PM2.5 from different aspects and levels.
Huang
Ninghua
N
Institute for Environmental Health and Related Product Safety, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Xu
Dongqun
D
D000393:Air Pollutants / Q000009:adverse effects*; D000818:Animals; D004391:Dust; D006801:Humans; D007109:Immunity / Q000187:drug effects*; D010316:Particle Size; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D001335:Vehicle Emissions / Q000009:adverse effects
D000393:Air Pollutants; D004391:Dust; D001335:Vehicle Emissions