title: Preventing seroma in the latissimus dorsi flap donor site with fibrin sealant.
abstract: Donor site seroma continues to be the most common complication of latissimus dorsi flap reconstruction. Numerous preventive methods and treatments have been described. The use of fibrin sealant in the donor site before closure may be an effective means of seroma prevention. The authors evaluated the efficacy of fibrin sealant in conjunction with closed suction drainage in a series of 17 latissimus flap donor sites. They also determined their approximate institutional seroma rate with a retrospective chart review of 20 donor sites. The fibrin sealant patients had a seroma rate of 11.8% compared with a rate of 35% among the untreated patients (P = 0.047). This compares favorably with seroma rates as high as 79% described in the literature. In conclusion, the use of fibrin sealant in the latissimus flap donor site appears to be effective in preventing seroma.
authors.affiliation: CHRISTUS St. Joseph Hospital, Plastic Surgery Residency Program, Houston, TX 77002, USA. jonweinrach@hotmail.com
authors.forename: Jonathan C
authors.initials: JC
authors.lastname: Weinrach
authors.forename: Ernest D
authors.initials: ED
authors.lastname: Cronin
authors.forename: Bruce K
authors.initials: BK
authors.lastname: Smith
authors.forename: Donald R
authors.initials: DR
authors.lastname: Collins
authors.forename: Benjamin E
authors.initials: BE
authors.lastname: Cohen
mesh_terms: D001943:Breast Neoplasms / Q000601:surgery; D005122:Exudates and Transudates; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006801:Humans; D016462:Mammaplasty; D011183:Postoperative Complications / Q000517:prevention & control*; D044967:Serum; D014014:Tissue Adhesives / Q000627:therapeutic use*
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives