Spectrum of anti-measles immunoglobulin G subclasses in convalescents after measles.
A simple semiquantitative method for measuring anti-measles IgG subclasses is developed on the basis of commercial diagnostic test system for measurements of anti-measles IgG and a kit of peroxidase-labeled monoclonal antibodies to human IgG subclasses. During the acute phase of the disease specific antibodies are presented mainly by IgG2 antibodies, while in subjects with a history of measles more than 10 years before 2 subgroups were detected, which responded by production of IgG2 or IgG1 subclasses.
Toptygina
A P
AP
G. N. Gabrichevskii Moscow Institute of Epidemiology and Microbiology, Moscow. toptyginaanna@km.ru
Pukhal'skii
A L
AL
Mamaeva
T A
TA
Aleshkin
V A
VA
D000328:Adult; D000368:Aged; D000888:Antibodies, Anti-Idiotypic; D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral / Q000097:blood / Q000145:classification*; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000379:methods; D007074:Immunoglobulin G / Q000097:blood / Q000145:classification*; D008297:Male; D008457:Measles / Q000276:immunology*; D008459:Measles virus / Q000276:immunology; D008875:Middle Aged
D000888:Antibodies, Anti-Idiotypic; D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D007074:Immunoglobulin G