title: Outcome of percutaneous coronary intervention versus coronary bypass grafting for patients with low left ventricular ejection fractions, unstable angina pectoris, and risk factors for adverse outcomes with bypass (the AWESOME Randomized Trial and Registry).
abstract: The recently concluded Angina With Extremely Serious Operative Mortality Evaluation (AWESOME) was a randomized clinical trial of percutaneous coronary intervention versus coronary bypass graft surgery among patients with medically refractory ischemia who were at high risk for coronary bypass graft surgery because of > or =1 risk factors that included severely reduced left ventricular (LV) function, defined as LV ejection fraction <35%. This study reports the outcome of patients with LV ejection fraction <35% in the randomized clinical trial and the physician-directed and patient choice registries of the AWESOME study.
authors.affiliation: New York VA Medical Center and New York University School of Medicine, New York, New York 10010, USA. steven.sedlis@med.va.gov
authors.forename: Steven P
authors.initials: SP
authors.lastname: Sedlis
authors.forename: Kodangudi B
authors.initials: KB
authors.lastname: Ramanathan
authors.forename: Douglass A
authors.initials: DA
authors.lastname: Morrison
authors.forename: Gulshan
authors.initials: G
authors.lastname: Sethi
authors.forename: Jerome
authors.initials: J
authors.lastname: Sacks
authors.forename: William
authors.initials: W
authors.lastname: Henderson
mesh_terms: D000368:Aged; D000787:Angina Pectoris / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D015906:Angioplasty, Balloon, Coronary; D002303:Cardiac Output, Low / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D001026:Coronary Artery Bypass; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012042:Registries; D016019:Survival Analysis; D016896:Treatment Outcome; D014481:United States