Molecular imprinting made easy.
A simple method of molecular imprinting is presented that uses a single cross-linking monomer N,O-bismethacryloyl ethanolamine (NOBE) along with template, initiator, and solvent. This formulation eliminates the need for additional functional monomers and empirical optimization of relative ratios of functional monomers, cross-linkers, and template. In fact, utilization of NOBE alone often provides molecularly imprinted polymers (MIPs) with higher performance than MIPs incorporating functional monomer (e.g., methacrylic acid).
Sibrian-Vazquez
Martha
M
Department of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, USA.
Spivak
David A
DA
D001665:Binding Sites; D002851:Chromatography, High Pressure Liquid; D003432:Cross-Linking Reagents / Q000737:chemistry*; D019856:Ethanolamine / Q000737:chemistry; D008689:Methacrylates / Q000737:chemistry; D015394:Molecular Structure; D009284:Naphthols / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry
D003432:Cross-Linking Reagents; D008689:Methacrylates; D009284:Naphthols; D011108:Polymers; D012997:Solvents; C008384:methacrylic acid; D019856:Ethanolamine; C028405:2-naphthol