[Circadian rhythm and encephalic vascular disease: a correlative study with risk factors].
The human biological mechanisms show a predictable clinical variability in time, which has allowed a deeper reevaluation of present-day medical practices, regarding the circadian rhythm (CR) and the mechanisms that produce the supported variations in all biological levels. We have made a study aiming to relate the CR and onset of the neurological clinic situation due to the encephalic vascular lesion, correlating with modifying risk factors. Fifty three patients were studied, 50,94% female (n=27) and 49,50% male (n=26), at average age 66.4 years old. Four intervals of six hours each (0-6; 6-12; 12-18; 18-24) were used to analyze the frequency of the ictus and the incidence in each interval. We found an incidence of 6(11.32%) patients in the 0-6 hs interval; 21 (39.62%) patients in the 6-12 hs interval; 10(18.86%) patients in the 12-18 hs interval; 16 (30.18%) patients in the 18-24 interval. A correlative study with the risk factors has shown that arterial hypertension [(81.25%)] and smoking habit [ (56.25)] were predominant during the 18-24 hs interval, while sedentary [11(52.38%)] stress [11(52.38%)] diabetes [(47.61%)] hyperlipidemia [8 (38.09%)] and alcoholism [8 (38.09%] were predominant during the 6-12 hs interval; and cardiac diseases in the 12-18hs interval.
Oliveira
Helio Araújo
HA
Serviço de Neurologia, Hospital Universitário, Universidade Federal de Sergipe, Aracaju, SE, Brasil. hélio@infonet.com.br
Moreira
Alvaro José Porto
AJ
Oliveira
Arthur Maynart Pereira
AM
D000368:Aged; D001938:Brazil / Q000453:epidemiology; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D006331:Heart Diseases / Q000150:complications; D006760:Hospitalization; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D018709:Statistics, Nonparametric; D013312:Stress, Physiological / Q000150:complications; D020521:Stroke / Q000209:etiology*; D013997:Time Factors; D014057:Tomography, X-Ray Computed