[Acute myocardial infarct with ST segment elevation--thrombolytic therapy].
The treatment of patients with acute myocardial infarction who present with the elevation of ST segment on electrocardiogram (STEAMI) is based on the need of re-establishing coronary blood flow through the occluded epicardial artery. This goal could be achieved using thrombolytic agents, or "mechanically" with percutaneous coronary interventions (PCI) or by urgent coronary surgery. A large number of STEAMI patients treated with thrombolysis, simple use of these drugs in almost all hospitals, and their efficacy are the main reasons for their use. A smaller number of patients in whom TIMI grade 3 flow could be achieved and higher early mortality of these patients are the reasons in favor of percutaneous coronary interventions. Early reocclusion rates, expensive equipment, small number of medical centers with skillful team for safe procedures, and the nature of these "mechanical" interventions for atherosclerosis which is a biologic phenomenon, speak against these procedures.
Kranjcević
Stjepan
S
Klinicka bolnica Merkur Zajceva 19 10000 Zagreb, Hrvatska.
D004562:Electrocardiography; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000503:physiopathology; D015912:Thrombolytic Therapy