Pineal parenchymal tumours: I. Pineocytoma: a tumour responsive to platinum-based chemotherapy.
Pineocytoma and pineoblastoma are now recognised as a spectrum of the same disease. Three cases of pineocytoma (grade I-II) are presented, in which platinum-based chemotherapy was used with some success, either as part of primary therapy or at the time of relapse. With the recent reclassification of pineal parenchymal tumours into a grade I-IV continuum, the place of chemotherapy, previously only well-established in pineoblastoma, is discussed.
Jackson
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AS
Department of Radiotherapy, St Bartholomew's Hospital, London, UK.
Plowman
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PN
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D016190:Carboplatin / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010870:Pineal Gland; D010871:Pinealoma / Q000175:diagnosis* / Q000188:drug therapy / Q000556:secondary; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000556:secondary; D014750:Vincristine / Q000008:administration & dosage
D014750:Vincristine; D005047:Etoposide; D016190:Carboplatin