title: Spectrum of anti-measles immunoglobulin G subclasses in convalescents after measles.
abstract: A simple semiquantitative method for measuring anti-measles IgG subclasses is developed on the basis of commercial diagnostic test system for measurements of anti-measles IgG and a kit of peroxidase-labeled monoclonal antibodies to human IgG subclasses. During the acute phase of the disease specific antibodies are presented mainly by IgG2 antibodies, while in subjects with a history of measles more than 10 years before 2 subgroups were detected, which responded by production of IgG2 or IgG1 subclasses.
authors.affiliation: G. N. Gabrichevskii Moscow Institute of Epidemiology and Microbiology, Moscow. toptyginaanna@km.ru
authors.forename: A P
authors.initials: AP
authors.lastname: Toptygina
authors.forename: A L
authors.initials: AL
authors.lastname: Pukhal'skii
authors.forename: T A
authors.initials: TA
authors.lastname: Mamaeva
authors.forename: V A
authors.initials: VA
authors.lastname: Aleshkin
mesh_terms: D000328:Adult; D000368:Aged; D000888:Antibodies, Anti-Idiotypic; D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral / Q000097:blood / Q000145:classification*; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000379:methods; D007074:Immunoglobulin G / Q000097:blood / Q000145:classification*; D008297:Male; D008457:Measles / Q000276:immunology*; D008459:Measles virus / Q000276:immunology; D008875:Middle Aged
chemical_list: D000888:Antibodies, Anti-Idiotypic; D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D007074:Immunoglobulin G