title: Conservative management of pulmonary lymphangioleiomyomatosis and tuberous sclerosis complicated by renal angiomyolipomas in pregnancy.
abstract: Both pulmonary lymphangioleiomyomatosis and tuberous sclerosis are rare diseases. The optimal management in pregnancy is unclear. A primigravida with pulmonary lymphangioleiomyomatosis and tuberous sclerosis complicated by worsening renal function secondary to angiomyolipomas was managed conservatively. Favorable maternal and neonatal outcomes were achieved. Pulmonary lymphangioleiomyomatosis is a consideration in tuberous sclerosis patients with respiratory symptoms. Tuberous sclerosis patients with pulmonary lymphangioleiomyomatosis require cautious and calculated expectant management in an effort to avoid adverse outcomes.
authors.affiliation: Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Columbia Presbyterian Medical Center, New York, New York, USA.
authors.forename: J
authors.initials: J
authors.lastname: Cleary-Goldman
authors.forename: A V
authors.initials: AV
authors.lastname: Sanghvi
authors.forename: G S
authors.initials: GS
authors.lastname: Nakhuda
authors.forename: J N
authors.initials: JN
authors.lastname: Robinson
mesh_terms: D000328:Adult; D018207:Angiomyolipoma / Q000150:complications* / Q000628:therapy; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications* / Q000628:therapy; D008175:Lung Neoplasms / Q000150:complications* / Q000628:therapy; D018192:Lymphangioleiomyomatosis / Q000150:complications* / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D014402:Tuberous Sclerosis / Q000150:complications*