Convergence of olfactory and gustatory connections onto the endopiriform nucleus in the rat.
Electrical and optical recordings were made from slice preparations including the piriform and gustatory cortices. Electrical stimulation of the gustatory cortex evoked a characteristic field potential in the endopiriform nucleus. A field potential was induced in the endopiriform nucleus by stimulation of the piriform cortex. Voltage-sensitive dye studies showed that stimulation of the piriform cortex induced signal propagation from the piriform cortex to endopiriform nucleus, whereas stimulation of the gustatory cortex did the same from the gustatory cortex to endopiriform nucleus via the agranular division of the insular cortex. After stimulation of the endopiriform nucleus, optical signals propagated not only to the piriform cortex but also to the gustatory cortex via the agranular division of the insular cortex. The olfactory and gustatory pathways appeared to be reciprocally connected. Unit recordings indicated that olfactory and gustatory activity converged onto a single neuron of the endopiriform nucleus. It is suggested that the cortical integration of olfactory and gustatory information could modulate mechanisms involved in food selection and emotional reactions relating to the chemical senses.
Fu
W
W
Department of Physiology, Kanazawa Medical University, Uchinada, Ishikawa 920-0293, Japan.
Sugai
T
T
Yoshimura
H
H
Onoda
N
N
D000818:Animals; D001931:Brain Mapping; D015740:Calcitonin Gene-Related Peptide / Q000378:metabolism; D002540:Cerebral Cortex / Q000166:cytology / Q000502:physiology*; D004558:Electric Stimulation / Q000379:methods; D005071:Evoked Potentials / Q000502:physiology / Q000528:radiation effects; D007150:Immunohistochemistry / Q000379:methods; D066298:In Vitro Techniques; D009474:Neurons / Q000502:physiology* / Q000528:radiation effects; D009830:Olfactory Bulb / Q000033:anatomy & histology / Q000502:physiology*; D009833:Olfactory Pathways / Q000502:physiology*; D018408:Patch-Clamp Techniques / Q000379:methods; D051381:Rats; D017208:Rats, Wistar; D018080:Receptors, GABA-B / Q000378:metabolism; D013997:Time Factors
D018080:Receptors, GABA-B; D015740:Calcitonin Gene-Related Peptide