Serum interleukin-6 in patients with adrenal tumors.
The mean blood content of interleukin-6 in patients with adrenal tumors was much higher than in healthy donors. No correlations were revealed between interleukin-6 level, patients sex and age, stage and duration of the disease. Interleukin-6 concentration was maximum in patients with adrenocortical cancer. A negative correlation was found between interleukin-6 level and blood cortisol concentration in patients with cortisol-producing adenoma. In patients with aldosterone-producing adenoma, interleukin-6 level tended to correlate negatively with plasma renin activity.
Kushlinskii
N E
NE
N. N. Blokhin Russian Oncological Center, Russian Academy of Medical Sciences.
Britvin
T A
TA
Kazantseva
I A
IA
Baronin
A A
AA
Polikarpova
S B
SB
Bogatyrev
O P
OP
Tishenina
R S
RS
Kalinin
A P
AP
D000236:Adenoma / Q000276:immunology / Q000378:metabolism; D000306:Adrenal Cortex Neoplasms / Q000276:immunology / Q000378:metabolism; D000310:Adrenal Gland Neoplasms / Q000276:immunology* / Q000378:metabolism; D000328:Adult; D000368:Aged; D000450:Aldosterone / Q000096:biosynthesis; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000096:biosynthesis / Q000097:blood; D015850:Interleukin-6 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012083:Renin / Q000097:blood
D015850:Interleukin-6; D000450:Aldosterone; D012083:Renin; D006854:Hydrocortisone