[Impaired hemostasis as a cause of intensified bleeding after heart surgery with extracorporeal blood circulation].
The paper contains the results of a retrospective analysis of causes for an intensified bleeding in patients operated on the heart with artificial blood circulation. An affected hemostasis plasma chain, i.e. insufficiency of blood coagulation factors due to hemodelution, hypofibrinogenemia etc., provoked the above disorder in 39% of patients with a higher postoperative bleeding. Additional reasons for the impaired hemostasis chain included: the "heparin-rebound" phenomenon (3.4%), activation of the secondary fibrinolysis (3.4%) and disseminated intravascular coagulation (DIC) (0.14%). Finally, an undiagnosed inadequate surgical hemostasis provoked an intense bleeding in 19.5% of cases.
Morozov
Iu A
IuA
Charnaia
M A
MA
Gladysheva
V G
VG
D001778:Blood Coagulation Disorders / Q000097:blood / Q000150:complications*; D001779:Blood Coagulation Factors / Q000032:analysis; D006348:Cardiac Surgical Procedures; D005112:Extracorporeal Circulation; D005260:Female; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D008297:Male; D019106:Postoperative Hemorrhage / Q000097:blood / Q000209:etiology*; D012189:Retrospective Studies
D001779:Blood Coagulation Factors