title: Comparison of flow artifacts between 2D-FLAIR and 3D-FLAIR sequences at 3 T.
abstract: It has been reported that 3D-FLAIR can reduce the flow artifact resulting from cerebrospinal fluid (CSF) at 1.5 T compared to 2D-FLAIR. Flow-related artifacts tend to be worse at 3 T than at 1.5 T. The purpose of this study was to compare the CSF flow artifacts of 2D-FLAIR and 3D-FLAIR sequences at 3 T in eight healthy volunteers. The grade of CSF-related artifacts were scored through observing the perimedullary cistern, cerebellopontine angle cisterns, fourth ventricule, prepontine cistern, suprasellar cistern, ambient cisterns, sylvian fissures, third ventricle and lateral ventricles. Grading was performed on either axial or sagittal images. The CSF in-flow artifact scores were significantly higher on axial 2D-FLAIR than on axial 3D-FLAIR MPR images in all areas except the bilateral sylvian fissures, and higher on sagittal 2D-FLAIR than on sagittal 3D-FLAIR MPR images in perimedullary, bilateral CP angle and suprasellar cisterns. The CSF-related flow artifacts were significantly reduced by 3D-FLAIR, while structures in the cistern were depicted more clearly, even at 3 T. Further study is necessary to compare the clinical efficacy between 2D-FLAIR and 3D-FLAIR in depicting subtle abnormalities.
authors.affiliation: Department of Radiology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Shouwa-ku, Nagoya, Japan. naganawa@med.nagoya-u.ac.jp
authors.forename: Shinji
authors.initials: S
authors.lastname: Naganawa
authors.forename: Tokiko
authors.initials: T
authors.lastname: Koshikawa
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Nakamura
authors.forename: Hisashi
authors.initials: H
authors.lastname: Kawai
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Fukatsu
authors.forename: Takeo
authors.initials: T
authors.lastname: Ishigaki
authors.forename: Tomomi
authors.initials: T
authors.lastname: Komada
authors.forename: Katsuya
authors.initials: K
authors.lastname: Maruyama
authors.forename: Osamu
authors.initials: O
authors.lastname: Takizawa
mesh_terms: D000328:Adult; D016477:Artifacts; D001921:Brain / Q000033:anatomy & histology*; D001927:Brain Diseases / Q000134:cerebrospinal fluid; D001932:Brain Neoplasms / Q000134:cerebrospinal fluid; D002530:Cerebellopontine Angle / Q000033:anatomy & histology; D002535:Cerebral Aqueduct / Q000033:anatomy & histology; D002555:Cerebrospinal Fluid / Q000502:physiology*; D002946:Cisterna Magna / Q000033:anatomy & histology; D005260:Female; D020546:Fourth Ventricle / Q000033:anatomy & histology; D006392:Hemangioma, Cavernous / Q000134:cerebrospinal fluid; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D020547:Lateral Ventricles / Q000033:anatomy & histology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid; D010296:Parietal Lobe / Q000473:pathology; D011149:Pons / Q000033:anatomy & histology; D020542:Third Ventricle / Q000033:anatomy & histology