A convenient synthesis of chiral nonracemic vinyl aziridines.
[reaction: see text] The preparation of a range of alkyl and aryl chiral vinyl aziridines was achieved in high yield and stereoselectivity, and with excellent diastereoselectivity, by reaction of tert-butylsulfinylimines with the ylide derived from S-allyl tetrahydrothiophenium bromide.
Morton
Daniel
D
School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich, NR4 7TJ, U.K.
Pearson
David
D
Field
Robert A
RA
Stockman
Robert A
RA