title: Conserved RNA secondary structures in viral genomes: a survey.
abstract: The genomes of RNA viruses often carry conserved RNA structures that perform vital functions during the life cycle of the virus. Such structures can be detected using a combination of structure prediction and co-variation analysis. Here we present results from pilot studies on a variety of viral families performed during bioinformatics computer lab courses in past years.
authors.affiliation: Institut für Theoretische Chemie und Molekulare Strukturbiologie, Universität Wien, Währingerstrasse 17, Vienna, A-1090, Austria. ivo@tbi.univie.ac.at
authors.forename: I L
authors.initials: IL
authors.lastname: Hofacker
authors.forename: P F
authors.initials: PF
authors.lastname: Stadler
authors.forename: R R
authors.initials: RR
authors.lastname: Stocsits
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D017124:Conserved Sequence / Q000235:genetics*; D030541:Databases, Genetic; D016679:Genome, Viral; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D012367:RNA, Viral / Q000235:genetics*; D012190:Retroviridae / Q000235:genetics*; D016415:Sequence Alignment / Q000379:methods; D017423:Sequence Analysis, RNA / Q000379:methods*
chemical_list: D012367:RNA, Viral