title: Pro-CAS: a prospective registry of carotid angioplasty and stenting.
abstract: OBJECTIVE
  The German Societies of Angiology and Radiology have instituted a prospective registry of carotid angioplasty and stenting (CAS) to limit uncontrolled use of CAS and to collect data about technique and results of CAS outside clinical trials.
  
  
  METHODS
  A total of 38 centers register their patients prospectively before CAS is performed. At discharge, technical details, periprocedural medication, and the clinical course are reported on a standardized form.
  
  
  RESULTS
  During the first 48 months, 3853 planned interventions were recorded, and CAS was actually attempted on 3267 patients of whom 1827 (56%) were symptomatic and 1433 (44%) were asymptomatic. In 3127 (98%) cases, stents were used, of which 2784 (89%) were of the self-expanding type. Other technical aspects such as the use of guiding catheters and protection devices varied widely among the centers. Periprocedural medication rather uniformly included aspirin and clopidogrel before and after CAS and high-dose heparin and atropin during CAS. CAS was successful in 3207 (98%) cases. There was a 0.6% (n=18) mortality rate, a 1.2% (n=38) major stroke rate, and a 1.3% (n=41) minor stroke rate. The combined stroke and death rate was 2.8% (n=90).
  
  
  CONCLUSIONS
  These prospective multicenter data are likely to give a realistic picture of the possibilities and limitations of CAS in the general community. They suggest that CAS may be performed with similar results in the general community as they have been reported by highly specialized centers and in clinical studies.
authors.affiliation: Medizinische Klinik der Technischen Universität, München, Germany. theiss@med1.med.tu-muenchen.de
authors.forename: Wolfram
authors.initials: W
authors.lastname: Theiss
authors.forename: Peter
authors.initials: P
authors.lastname: Hermanek
authors.forename: Klaus
authors.initials: K
authors.lastname: Mathias
authors.forename: Ramazanali
authors.initials: R
authors.lastname: Ahmadi
authors.forename: Lothar
authors.initials: L
authors.lastname: Heuser
authors.forename: Franz-Josef
authors.initials: FJ
authors.lastname: Hoffmann
authors.forename: Rüdiger
authors.initials: R
authors.lastname: Kerner
authors.forename: Franz
authors.initials: F
authors.lastname: Leisch
authors.forename: Horst
authors.initials: H
authors.lastname: Sievert
authors.forename: Stefan
authors.initials: S
authors.lastname: von Sommoggy
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017130:Angioplasty / Q000706:statistics & numerical data*; D016893:Carotid Stenosis / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D003952:Diagnostic Imaging / Q000706:statistics & numerical data; D004691:Endarterectomy / Q000706:statistics & numerical data; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D002546:Ischemic Attack, Transient / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012042:Registries; D015607:Stents / Q000706:statistics & numerical data*; D020521:Stroke / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D017131:Thrombectomy / Q000706:statistics & numerical data; D016896:Treatment Outcome