A sudden death during a saline drip in a schizophrenic patient with polydipsia.
A young woman with polydipsia died suddenly while receiving a normal saline drip in a hospital for psychiatric care. Slight symptoms due to water intoxication, more specifically, nausea, vomiting, and anorexia, appeared and her serum sodium and potassium measured 106 and 1.7 mEq/l, respectively. General convulsions are thought to be the most common result of water intoxication in emergency cases, however, when she was found with circulatory collapse, no severe neurological symptoms were present. The cause of her collapse did not seem to be due to hyponatremia but to hypopotassemia. Although epinephrine is contraindicated with some psychiatric drugs, the doctor used it to raise blood pressure in treating circulatory collapse. It is possible that epinephrine induced cardiac arrest.
Mimasaka
Sohtaro
S
Division of Forensic medicine, Department of Public Health and Forensic Medicine, Tohoku University School of Medicine, Sendai 980-8575, Japan.
Funayama
Masato
M
Nata
Masayuki
M
D000328:Adult; D003645:Death, Sudden / Q000209:etiology*; D004326:Drinking; D004837:Epinephrine / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D012559:Schizophrenia / Q000150:complications*; D012769:Shock / Q000188:drug therapy / Q000209:etiology; D012965:Sodium Chloride / Q000008:administration & dosage* / Q000506:poisoning*; D014869:Water Intoxication / Q000150:complications*; D014882:Water-Electrolyte Balance
D012965:Sodium Chloride; D004837:Epinephrine