title: [Effect of lycopene on DNA oxidative damage of cells in rats].
abstract: OBJECTIVE
  Observe the protective effect of Lycopene(LP) on DNA damage.
  
  
  METHODS
  Rats were given LP after 4 weeks, the DNA break in peripheral blood lymphocytes and liver cells from the rats were analyzed with single cell gel electrophoresis.
  
  
  RESULTS
  Compared with control, the damage of DNA in LP group were reduced significantly(P < 0.05).
  
  
  CONCLUSIONS
  LP could protect DNA damage of peripheral blood lymphocytes and liver cells in rats.
authors.affiliation: Public Health School of Harbin Medical University, Harbin 150001, China.
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Pan
authors.forename: Lixin
authors.initials: L
authors.lastname: Na
authors.forename: Gang
authors.initials: G
authors.lastname: Shi
authors.forename: Xingsan
authors.initials: X
authors.lastname: Li
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002338:Carotenoids / Q000494:pharmacology*; D020552:Comet Assay; D004249:DNA Damage / Q000187:drug effects*; D022781:Hepatocytes / Q000648:ultrastructure; D000077276:Lycopene; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000975:Antioxidants; D002338:Carotenoids; D000077276:Lycopene