SERRS as a more sensitive technique for the detection of labelled oligonucleotides compared to fluorescence.
This communication contains data from a comparison between the detection limits obtained using surface enhanced resonance Raman scattering (SERRS) and fluorescence detection of dye labelled oligonucleotides. The results show that the detection limits for SERRS are generally at least three orders of magnitude lower than those obtained for fluorescence.
Faulds
Karen
K
University of Strathclyde, Dept. Pure and Applied Chemistry, 295 Cathedral Street, Glasgow, UKG1 1XL.
Barbagallo
Romina P
RP
Keer
Jacquie T
JT
Smith
W Ewen
WE
Graham
Duncan
D
D000818:Animals; D005456:Fluorescent Dyes; D009841:Oligonucleotides / Q000032:analysis*; D012680:Sensitivity and Specificity; D013059:Spectrum Analysis, Raman / Q000379:methods
D005456:Fluorescent Dyes; D009841:Oligonucleotides