The relationship between hypoalbuminaemia, tumour volume and the systemic inflammatory response in patients with colorectal liver metastases.
The relationship between hypoalbuminaemia, tumour volume and C-reactive protein was examined in patients with colorectal liver metastases (n=57). On multiple regression analysis, albumin concentrations were independently associated with C-reactive protein (r=0.56, P<0.001) but not percentage hepatic replacement (P=0.34). These results show that hypoalbuminaemia is associated with the presence of a systemic inflammatory response rather than tumour volume in patients with colorectal liver metastases.
Al-Shaiba
R
R
University Department of Surgery, Royal Infirmary, Glasgow G31 2ER, UK.
McMillan
D C
DC
Angerson
W J
WJ
Leen
E
E
McArdle
C S
CS
Horgan
P
P
D000368:Aged; D000369:Aged, 80 and over; D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis; D015179:Colorectal Neoplasms / Q000201:enzymology / Q000473:pathology*; D005260:Female; D006801:Humans; D034141:Hypoalbuminemia / Q000209:etiology*; D007249:Inflammation / Q000209:etiology; D008111:Liver Function Tests; D008113:Liver Neoplasms / Q000201:enzymology / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D012709:Serum Albumin / Q000032:analysis
D012709:Serum Albumin; D002097:C-Reactive Protein; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase