title: Clinical evaluation of enhanced nonablative skin rejuvenation using a combination of a 532 and a 1,064 nm laser.
abstract: OBJECTIVE
  Improvements in the physical signs of photoaging can be achieved by non-invasive laser resurfacing procedures. To evaluate the effectiveness and safety of the Nd:YAG 1,064 nm and KTP 532 nm lasers for non-invasive skin rejuvenation.
  
  
  METHODS
  Subjects requesting non-invasive skin rejuvenation underwent two treatments with the 532 nm laser to one side of the face and with both lasers to the other side, followed by three treatments with the 1,064 nm laser to both sides. Skin characteristics were evaluated before, during, and up to 4 months after treatment.
  
  
  RESULTS
  A >25% improvement in overall skin condition was observed for >30% of subjects at the 1 month follow-up and >40% of subjects at the 4 month follow-up. The greatest improvements were observed for visual dryness, roughness, and uneven pigmentation. No adverse events were reported. There was a trend for greater improvement in patients who received more 1,064 nm treatments but this was not statistically significant.
  
  
  CONCLUSIONS
  The 532 nm KTP and 1,064 nm Nd: YAG lasers can be effectively and safely used for non-invasive skin rejuvenation.
authors.affiliation: Skincare Physicians, Chestnut Hill, Massachusetts 02467, USA.
authors.forename: Mei-Heng
authors.initials: MH
authors.lastname: Tan
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Dover
authors.forename: Te-Shao
authors.initials: TS
authors.lastname: Hsu
authors.forename: Kenneth A
authors.initials: KA
authors.lastname: Arndt
authors.forename: Brigitte
authors.initials: B
authors.lastname: Stewart
mesh_terms: D003131:Combined Modality Therapy; D006801:Humans; D053685:Laser Therapy; D028022:Low-Level Light Therapy; D015595:Skin Aging