The factors affecting glycemic control in Japanese adolescents with type 2 diabetes mellitus.
The factors affecting glycemic control were examined using HbA(1C) as an index in a total of 22 patients with type 2 diabetes mellitus whose ages at onset were less than 18 years old. As a result, the presence or absence of the following cases were considered possible factors for significant exacerbation of glycemic control: diabetic microangiopathy; school phobia or nonworking situation; drug therapy; use of more than two kinds of oral hypoglycemic agents (OHAs) or insulin for the drug therapy cases. No improvement in glycemic control could be achieved even by increasing the number of OHAs for co-administration or by insulin use unless dietary/exercise therapy, a basic therapeutic option, was adequately performed.
Ohki
Yukashi
Y
Department of Pediatrics, Nippon Medical School. yukashi@nms.ac.jp
Kishi
Megumi
M
Orimo
Hiromi
H
Ohkawa
Takuya
T
D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D002648:Child; D002675:Child, Preschool; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis / Q000523:psychology / Q000628:therapy*; D003925:Diabetic Angiopathies / Q000209:etiology / Q000517:prevention & control; D003927:Diet, Diabetic; D004359:Drug Therapy, Combination; D005081:Exercise Therapy; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007223:Infant; D007328:Insulin / Q000627:therapeutic use; D007564:Japan; D008297:Male; D010698:Phobic Disorders / Q000209:etiology / Q000517:prevention & control; D011788:Quality of Life
D015415:Biomarkers; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin