title: [Impaired hemostasis as a cause of intensified bleeding after heart surgery with extracorporeal blood circulation].
abstract: The paper contains the results of a retrospective analysis of causes for an intensified bleeding in patients operated on the heart with artificial blood circulation. An affected hemostasis plasma chain, i.e. insufficiency of blood coagulation factors due to hemodelution, hypofibrinogenemia etc., provoked the above disorder in 39% of patients with a higher postoperative bleeding. Additional reasons for the impaired hemostasis chain included: the "heparin-rebound" phenomenon (3.4%), activation of the secondary fibrinolysis (3.4%) and disseminated intravascular coagulation (DIC) (0.14%). Finally, an undiagnosed inadequate surgical hemostasis provoked an intense bleeding in 19.5% of cases.
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Morozov
authors.forename: M A
authors.initials: MA
authors.lastname: Charnaia
authors.forename: V G
authors.initials: VG
authors.lastname: Gladysheva
mesh_terms: D001778:Blood Coagulation Disorders / Q000097:blood / Q000150:complications*; D001779:Blood Coagulation Factors / Q000032:analysis; D006348:Cardiac Surgical Procedures; D005112:Extracorporeal Circulation; D005260:Female; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D008297:Male; D019106:Postoperative Hemorrhage / Q000097:blood / Q000209:etiology*; D012189:Retrospective Studies
chemical_list: D001779:Blood Coagulation Factors