Increased anterior corpus callosum size associated positively with hypnotizability and the ability to control pain.
This is the first MRI study to report differences in brain structure size between low and highly hypnotizable, healthy, right-handed young adults. Participants were stringently screened for hypnotic susceptibility with two standardized scales, and then exposed to hypnotic analgesia training to control cold pressor pain. Only the highly hypnotizable subjects (HHs) who eliminated pain perception were included in the present study. These HHs, who demonstrated more effective attentional and inhibitory capabilities, had a significantly (P < 0.003) larger (31.8%) rostrum, a corpus callosum area involved in the allocation of attention and transfer of information between prefrontal cortices, than low hypnotizable subjects (LHs). These results provide support to the neuropsychophysiological model that HHs have more effective frontal attentional systems implementing control, monitoring performance and inhibiting unwanted stimuli from conscious awareness, than LHs.
Horton
James E
JE
Department of Social and Behavioral Sciences, The University of Virginia's College at Wise, 1 College Avenue, Wise, VA 24293-4412, USA. jhorton@uvawise.edu
Crawford
Helen J
HJ
Harrington
Gregory
G
Downs
J Hunter
JH
D000293:Adolescent; D000328:Adult; D001288:Attention / Q000502:physiology; D003080:Cold Temperature; D003337:Corpus Callosum / Q000033:anatomy & histology* / Q000502:physiology; D005260:Female; D006801:Humans; D006990:Hypnosis; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging; D008297:Male; D010146:Pain / Q000473:pathology; D059408:Pain Management; D015203:Reproducibility of Results