title: SERRS as a more sensitive technique for the detection of labelled oligonucleotides compared to fluorescence.
abstract: This communication contains data from a comparison between the detection limits obtained using surface enhanced resonance Raman scattering (SERRS) and fluorescence detection of dye labelled oligonucleotides. The results show that the detection limits for SERRS are generally at least three orders of magnitude lower than those obtained for fluorescence.
authors.affiliation: University of Strathclyde, Dept. Pure and Applied Chemistry, 295 Cathedral Street, Glasgow, UKG1 1XL.
authors.forename: Karen
authors.initials: K
authors.lastname: Faulds
authors.forename: Romina P
authors.initials: RP
authors.lastname: Barbagallo
authors.forename: Jacquie T
authors.initials: JT
authors.lastname: Keer
authors.forename: W Ewen
authors.initials: WE
authors.lastname: Smith
authors.forename: Duncan
authors.initials: D
authors.lastname: Graham
mesh_terms: D000818:Animals; D005456:Fluorescent Dyes; D009841:Oligonucleotides / Q000032:analysis*; D012680:Sensitivity and Specificity; D013059:Spectrum Analysis, Raman / Q000379:methods
chemical_list: D005456:Fluorescent Dyes; D009841:Oligonucleotides