title: THEORETICAL DESIGN CONSIDERATIONS AND PHYSIOLOGIC PERFORMANCE CRITERIA FOR AN IMPROVED INTRACORPOREAL (ABDOMINAL) ELECTRICALLY ACTUATED LONG-TERM LEFT VENTRICULAR ASSIST DEVICE ("E-TYPE" ALVAD) OR PARTIAL ARTIFICIAL HEART.
abstract: Our laboratories are engaged in the design of a clinically-oriented electrically actuated long-term intracorporeal (abdominal) left ventricular assist device ("E-type" ALVAD) or partial artificial heart. This infradiaphragmatic blood pump is designed to be powered by implantable electrical to mechanical energy converter systems. THE FOLLOWING ANALYSES WERE UNDERTAKEN TO: [List: see text] The proposed "E-type" ALVAD should be capable of pumping 4-7 liters per minute at heart rates of 75-100 beats per minute during rest, and 10 liters per minute at rates of 120 beats per minute during moderate exercise. These performance levels should be exceeded with a maximum device stroke volume of 85-90 ml and a mean pump inflow (filling) impedance of </= 0.072 gm/sec/cm(-5).
authors.affiliation: Cardiovascular Surgical Research Laboratories, Texas Heart Institute of St. Luke's Episcopal and Texas Children's Hospitals, P.O. Box 20269, Houston, Texas 77025.
authors.forename: Stephen R.
authors.initials: SR
authors.lastname: Igo
authors.forename: C Wayne
authors.initials: CW
authors.lastname: Hibbs
authors.forename: John M.
authors.initials: JM
authors.lastname: Fuqua
authors.forename: Ruben
authors.initials: R
authors.lastname: Trono
authors.forename: Charles H.
authors.initials: CH
authors.lastname: Edmonds
authors.forename: John C.
authors.initials: JC
authors.lastname: Norman