title: Personality disorders in a total population twin cohort with eating disorders.
abstract: Findings regarding the occurrence of personality disorders (PDs) in eating disorders (EDs) have been contradictory. Most previous studies have been clinic-based. The aims of the current study were to assess the prevalence of PD in ED in a population-based twin group and to establish the distribution of PD in three subgroups of ED. A two-step screening and diagnostic study of ED was performed in a large Danish twin population. Axis I and axis II DSM-III-R and DSM-IV ED diagnoses were made on the basis of results obtained at clinical investigations and interviews. Forty-nine percent of the participants with ED had at least one PD, compared to 26% in those with no ED (P <.001). Cluster C PD was the most common type of PD in all subgroups of ED, and cluster B PD was found only in participants with bulimic symptoms. Genetic factors appeared to contribute significantly to the variance of cluster C PD in ED, which was evaluated as a possibly important background factor in ED.
authors.affiliation: Department of Psychiatry, Odense University Hospital, Odense, Denmark.
authors.forename: K
authors.initials: K
authors.lastname: Ilkjaer
authors.forename: L
authors.initials: L
authors.lastname: Kortegaard
authors.forename: K
authors.initials: K
authors.lastname: Hoerder
authors.forename: J
authors.initials: J
authors.lastname: Joergensen
authors.forename: K
authors.initials: K
authors.lastname: Kyvik
authors.forename: C
authors.initials: C
authors.lastname: Gillberg
mesh_terms: D016000:Cluster Analysis; D015331:Cohort Studies; D015897:Comorbidity; D003718:Denmark / Q000453:epidemiology; D039721:Diagnostic and Statistical Manual of Mental Disorders; D004200:Diseases in Twins / Q000453:epidemiology*; D001068:Feeding and Eating Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D010554:Personality Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D015995:Prevalence; D011795:Surveys and Questionnaires