title: Successful treatment of acrodermatitis continua suppurativa with topical tacrolimus 0.1% ointment.
abstract: Acrodermatitis continua suppurativa of Hallopeau (ACS) is a rare pustular variant of psoriasis in which numerous treatment modalities have been used without any consistent long-term effect. We report for the first time two patients with ACS which was successfully treated with topical tacrolimus 0.1% ointment. Our observations raise hopes that this new treatment strategy for ACS may constitute a novel effective therapeutic option for this recalcitrant condition.
authors.affiliation: Department of Dermatology, University of Bonn, 53105, Germany. dagmar.wilsmann-theis@ukb.uni-bonn.de
authors.forename: D
authors.initials: D
authors.lastname: Wilsmann-Theis
authors.forename: T
authors.initials: T
authors.lastname: Hagemann
authors.forename: H
authors.initials: H
authors.lastname: Dederer
authors.forename: J
authors.initials: J
authors.lastname: Wenzel
authors.forename: T
authors.initials: T
authors.lastname: Bieber
authors.forename: N
authors.initials: N
authors.lastname: Novak
mesh_terms: D000169:Acrodermatitis / Q000188:drug therapy*; D000287:Administration, Topical; D000368:Aged; D000369:Aged, 80 and over; D001458:Bandages; D004334:Drug Administration Schedule; D005260:Female; D005533:Foot Dermatoses / Q000188:drug therapy*; D006229:Hand Dermatoses / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D016559:Tacrolimus / Q000008:administration & dosage* / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus