Are the new quinolones appropriate treatment for community-acquired methicillin-resistant Staphylococcus aureus?
The use of quinolones in the treatment of non-serious community-acquired methicillin-resistant Staphylococcus aureus is discussed. The new C8-modified quinolones may be suitable for such treatment but controlled trials should be carried out to ensure that the pharmacokinetics are such that there is little risk of resistance developing.
Shopsin
Bo
B
Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.
Zhao
Xilin
X
Kreiswirth
Barry N
BN
Tillotson
Glenn S
GS
Drlica
Karl
K
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017714:Community-Acquired Infections / Q000188:drug therapy*; D006801:Humans; D016106:Methicillin Resistance; D015363:Quinolones / Q000627:therapeutic use*; D013203:Staphylococcal Infections / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D015363:Quinolones