Nickel-catalyzed cross-couplings of organosilicon reagents with unactivated secondary alkyl bromides.
A metal-catalyzed cross-coupling of organosilicon compounds with alkyl halides has been developed. Noteworthy attributes of the method are its scope (secondary electrophiles), its high functional-group compatibility, and the air stability of the catalyst components.
Powell
David A
DA
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Fu
Gregory C
GC
D002384:Catalysis; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000737:chemistry; D007202:Indicators and Reagents; D008670:Metals / Q000737:chemistry; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry; D012828:Silicones / Q000737:chemistry*
D006842:Hydrocarbons, Brominated; D006846:Hydrocarbons, Halogenated; D007202:Indicators and Reagents; D008670:Metals; D009942:Organometallic Compounds; D012828:Silicones; D009532:Nickel