[Intraoperative anaphylactic/anaphylactoid reaction to infusion of a modified liquid gelatin].
A clinical observation of an extremely rare but highly severe complication, i.e. anaphylatic/anaphylactoid reaction to the infusion of a synthetic colloid plasma-expander (Gelofusion) is described in the paper. Dropping arterial pressure concurrent with tachycardia and a negative dynamics of ST segment in ECGS were the main reaction signs. Besides, mechanisms of allergic reactions developing during the anesthesia implementation as well as the related measures of prevention and therapy are also elucidated.
Israelian
L A
LA
Lubnin
A Iu
AIu
D000707:Anaphylaxis / Q000097:blood / Q000139:chemically induced* / Q000188:drug therapy / Q000503:physiopathology; D000768:Anesthesia, General; D001784:Blood Gas Analysis; D005260:Female; D005780:Gelatin / Q000008:administration & dosage / Q000009:adverse effects*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D011695:IgA Vasculitis / Q000097:blood / Q000139:chemically induced* / Q000188:drug therapy / Q000503:physiopathology; D007431:Intraoperative Complications; D008577:Meningeal Neoplasms / Q000601:surgery*; D008579:Meningioma / Q000601:surgery*; D008875:Middle Aged; D010952:Plasma Substitutes / Q000008:administration & dosage / Q000009:adverse effects*; D013386:Succinates / Q000008:administration & dosage / Q000009:adverse effects*; D016896:Treatment Outcome
D010952:Plasma Substitutes; D013386:Succinates; C060085:succinylated gelatin; D005780:Gelatin