Eosinophilic folliculitis in a patient after allogeneic bone marrow transplantation: case report and review of the literature.
We describe a patient with eosinophilic folliculitis (EF) that developed 3 months after allogeneic bone marrow transplantation (BMT) for chronic myelogenous leukemia. Skin biopsy specimen revealed numerous eosinophil infiltrations from the hair follicles to the sebaceous glands. No sign of skin graft-versus-host disease (GVHD) was found. The skin lesions and peripheral eosinophilia subsided within 5 weeks. In the following 8 months, the rash did not recur and GVHD has not developed. Taken together with previous reports, the present case demonstrates that it is important to recognize this distinct skin condition to avoid an inference that it may manifest itself as one of the signs of skin GVHD.
Ota
Mitsuhito
M
Department of Dermatology, Hokkaido University Graduate School of Medicine, N-15 W-7, Sapporo 060-8638, Japan. ota@med.hokudai.ac.jp
Shimizu
Tadamichi
T
Hashino
Satoshi
S
Shimizu
Hiroshi
H
D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D004804:Eosinophils / Q000473:pathology*; D005260:Female; D005499:Folliculitis / Q000209:etiology / Q000473:pathology*; D016313:Genes, abl / Q000235:genetics; D006086:Graft vs Host Disease / Q000473:pathology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics / Q000601:surgery; D012333:RNA, Messenger / Q000032:analysis; D012867:Skin / Q000473:pathology; D014184:Transplantation, Homologous
D012333:RNA, Messenger