The role of fine needle aspiration cytology and imprint cytology in cervical lymphadenopathy.
OBJECTIVE
To determine the diagnostic accuracy of cervical lymphadenopathy by fine needle aspiration (FNAC) and imprint cytology (IC).


METHODS
This study included 94 patients with cervical lymphadenopathy. This study was carried out in the Departments of General Surgery and Pathology, King Fahad Hospital, Hofuf, Kingdom of Saudi Arabia, from June 2001 through to July 2002. They were subjected to clinical examination and FNAC of one of the enlarged lymph nodes. This was followed by IC and histological examination of this lymph node after its excision.


RESULTS
Clinical examination was correct in 78% of the cases. The overall accuracy of fine needle aspiration was 93%. It was accurate on all cases of reactive hyperplasia, 93% of tuberculosis lymphadenitis, 90% in Hodgkin's lymphoma, 86% in non-Hodgkin's lymphoma, and 91% of metastasis lymphadenopathy. On the other hand, the overall accuracy of IC was higher than that of fine needle aspiration, being 97%. It diagnosed all cases of reactive hyperplasia and non-Hodgkin's lymphoma, 97% in tuberculosis lymphadenitis, 90% in Hodgkin's lymphoma and 95% in metastasis lymphadenopathy.


CONCLUSIONS
These techniques proved to be reliable, rapid, and inexpensive procedures in diagnosis of lymphadenopathy. They can differentiate well between inflammatory and neoplastic lesions, in cases of lymphoma, cytological diagnosis should be followed by histological diagnosis for accurate classification and grading.
Al-Mulhim
Abdulrahman S
AS
Department of Surgery, King Fahad Hospital, Hofuf, Kingdom of Saudi Arabia. abdu3939@yahoo.com
Al-Ghamdi
Ali Maqbol A
AM
Al-Marzooq
Youssef M
YM
Hashish
Hany M
HM
Mohammad
Hamdoun A
HA
Ali
Adel M
AM
Gharib
Ibrahim A
IA
D000328:Adult; D001707:Biopsy, Needle; D003584:Cytological Techniques; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology*; D008206:Lymphatic Diseases / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D008297:Male; D009333:Neck / Q000601:surgery; D011237:Predictive Value of Tests; D012529:Saudi Arabia