Mycobacterium xenopi infection in an immunosuppressed patient with Crohn's disease.
A 48 year old patient with active Crohn's disease presented with bilateral nodules over his lungs resembling malignant metastasis. Bronchoscopic and pathological examination of the airways and sputum did not show any malignancy. After 6 weeks Mycobacterium xenopi was cultured from his bronchial washings while all other cultures remained negative. Treatment was started with rifampicin, ethambutol, and clarithromycin and, after 9 months of treatment, there was an almost complete resolution of his chest radiograph.
Majoor
C J
CJ
Department of Pulmonary Diseases, Jeroen Bosch Hospital, 5200 ME 's Hertogenbosch, The Netherlands. cjmajoor@planet.nl
Schreurs
A J M
AJ
Weers-Pothoff
G
G
D000893:Anti-Inflammatory Agents / Q000009:adverse effects; D001379:Azathioprine / Q000009:adverse effects; D003424:Crohn Disease / Q000150:complications* / Q000188:drug therapy; D003937:Diagnosis, Differential; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008175:Lung Neoplasms / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000150:complications* / Q000000981:diagnostic imaging; D019912:Mycobacterium xenopi; D009894:Opportunistic Infections / Q000150:complications* / Q000000981:diagnostic imaging; D011241:Prednisone / Q000009:adverse effects; D014057:Tomography, X-Ray Computed; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000000981:diagnostic imaging
D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D001379:Azathioprine; D011241:Prednisone