[Functional abnormality of adipocytes in the metabolic syndrome].
It becomes now evident that the localization of accumulated adipose mass is more important than the quantity of those in humans for the development of insulin resistance, which is based on the metabolic syndrome. The fat accumulation in visceral or subcutaneous area is closely related with the occurrence and severity of abnormality of glucose or lipid metabolism. The functional disturbance of adipose cells depending on the accumulated areas might cause the formation of metabolic disorders in the metabolic syndrome.
Bujo
Hideaki
H
Department of Genome Research and Clinical Application, Graduate School of Medicine, Chiba University.
D017667:Adipocytes / Q000378:metabolism / Q000502:physiology*; D000818:Animals; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology; D024821:Metabolic Syndrome / Q000378:metabolism*