Sustained remission of treatment-resistant cutaneous T-cell lymphoma with oral bexarotene.
Cutaneous T-cell lymphomas (CTCL) encompass a spectrum of clinical and histologic variants, characterized by malignant CD4+ T lymphocytes in the skin and visceral organs. This is a case report of a 74-year-old man with CTCL, including ulcerative lesions, resistant to multiple systemic therapies. Treatment with oral bexarotene resulted in rapid and sustained remission of both cutaneous and systemic symptoms.
Mehlmauer
Marilyn A
MA
Huntington Memorial Hospital, Pasadena, CA, USA. mmehlmauermd@earthlink.net
D000284:Administration, Oral; D000368:Aged; D016588:Anticarcinogenic Agents / Q000627:therapeutic use*; D000077610:Bexarotene; D006801:Humans; D008297:Male; D009182:Mycosis Fungoides / Q000188:drug therapy* / Q000473:pathology; D012074:Remission Induction; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology; D013764:Tetrahydronaphthalenes / Q000627:therapeutic use*
D016588:Anticarcinogenic Agents; D013764:Tetrahydronaphthalenes; D000077610:Bexarotene