title: Anticarcinogenic activity of Withania somnifera Dunal against Dalton's ascitic lymphoma.
abstract: The effect of ethanolic extract of the root of Withania somnifera Dunal (REWS) against Dalton's Ascitic Lymphoma has been evaluated in Swiss albino mice. A significant increase in the life span and a decrease in the cancer cell number and tumour weight were noted in the tumour-induced mice after treatment with REWS. The hematological parameters were also corrected by REWS in tumour-induced mice. These observations are suggestive of the protective effect of REWS in Dalton's Ascitic Lymphoma (DAL).
authors.affiliation: Division of Pharmacology, K.M. College of Pharmacy, Uthangudi, Melur Road, Madurai 625 107, Tamil Nadu, India. tinatina38@rediffmail.com
authors.forename: A J M
authors.initials: AJ
authors.lastname: Christina
authors.forename: D Gladwin
authors.initials: DG
authors.lastname: Joseph
authors.forename: M
authors.initials: M
authors.lastname: Packialakshmi
authors.forename: R
authors.initials: R
authors.lastname: Kothai
authors.forename: S Jerry Heison
authors.initials: SJ
authors.lastname: Robert
authors.forename: N
authors.initials: N
authors.lastname: Chidambaranathan
authors.forename: M
authors.initials: M
authors.lastname: Ramasamy
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001201:Ascites / Q000188:drug therapy / Q000473:pathology; D008223:Lymphoma / Q000188:drug therapy / Q000473:pathology; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000188:drug therapy / Q000473:pathology; D010529:Peritoneal Cavity / Q000166:cytology; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018517:Plant Roots; D032341:Withania
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts