Proliferation and differentiation processes in the heart muscle elements in different phylogenetic groups.
This article reviews, discusses, and summarizes data about the generative behavior of muscle tissue cells, the mechanisms of its regulation, and the organization of the endocrine function of the heart in the main phylogenetic groups. With respect to the ratio of processes of proliferation and differentiation, cell organization, and growth mechanism, muscle tissues of propulsive organs can be divided into three types, each revealed in one of three main groups of animals, lophotrochozoans, ecdysozoans, and chordates. Ecdysterone is likely to play the key role in the regulation of proliferation and differentiation processes in the heart muscle of crustaceans, and, most probably, also of molluscs. In each of the three main phylogenetic groups the endocrine function of the heart consisting of secretion of natriuretic peptides has a peculiar organization. Vertebrate cardiomyocytes are known to combine contractile and endocrine differentiation. Such functional dualism is absent in heart muscle elements of Lophotrochozoa and Ecdysozoa; in the heart of lopfotrochozoans, secretion of natriuretic peptides is performed by endothelial cells and their derivatives. Homology of the heart muscle in the animal kingdom as well as possible mechanisms of genomic and epigenomic regulation of different types of cardiomyogenesis are discussed.
Martynova
Marina G
MG
Institute of Cytology, Russian Academy of Sciences, 194064 St. Petersburg, Russia.
D000818:Animals; D002454:Cell Differentiation / Q000502:physiology*; D002455:Cell Division / Q000502:physiology; D004441:Ecdysterone / Q000378:metabolism; D004703:Endocrine System / Q000378:metabolism; D006321:Heart / Q000196:embryology* / Q000378:metabolism; D006801:Humans; D007448:Invertebrates / Q000196:embryology*; D009206:Myocardium / Q000166:cytology* / Q000378:metabolism*; D045265:Natriuretic Peptides / Q000378:metabolism; D010802:Phylogeny; D014714:Vertebrates / Q000196:embryology*
D045265:Natriuretic Peptides; D004441:Ecdysterone