Antiretroviral treatment of maternal HIV infection.
OBJECTIVE
One of my pregnant patients tested positive for human immunodeficiency virus. Will HIV therapy put her pregnancy outcome at risk?


CONCLUSIONS
The biggest risk is vertical transmission of HIV to her baby. She should be treated with combination therapy; triple therapy is required to reduce vertical transmission. Zidovudine is not teratogenic in humans, but information on other antiretroviral drugs is incomplete.
Talaie
Haleh
H
Hospital for Sick Children, Toronto, Ont.
Nava-Ocampo
Alejandro A
AA
Koren
Gideon
G
D019380:Anti-HIV Agents / Q000627:therapeutic use*; D002170:Canada; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000517:prevention & control* / Q000635:transmission; D015497:HIV-1; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy* / Q000821:virology*; D012307:Risk Factors; D016387:Women's Health
D019380:Anti-HIV Agents