title: [Self-limited thrombotic microangiopathy associated with perianal abscess].
abstract: A 43-year-old female with Staphyloccocus-induced perianal abscess, was admitted to hospital because of a clinical picture of acute renal failure and thrombotic microangiopathy. Schistocytes, thrombopenia, a negative Coombs test and no detectable plasma haptoglobin were diagnostic for thrombotic microangiopathy. Antibiotics, surgical drainage, plasmapheresis and fresh frozen plasma were given with a favourable evolution. We review the prognostic factors determining recovery of renal function and hematological abnormalities.
authors.affiliation: Servicio de Nefrología, Hospital Universitario Miguel Servet, Zaragoza.
authors.forename: B
authors.initials: B
authors.lastname: Campos
authors.forename: O
authors.initials: O
authors.lastname: Gracia
authors.forename: A
authors.initials: A
authors.lastname: Sanjuán
authors.forename: M A
authors.initials: MA
authors.lastname: Arto
authors.forename: J A
authors.initials: JA
authors.lastname: Gutiérrez
mesh_terms: D000038:Abscess / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D058186:Acute Kidney Injury / Q000209:etiology*; D000328:Adult; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000627:therapeutic use; D001003:Anal Canal; D003646:Debridement; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000209:etiology* / Q000628:therapy; D006801:Humans; D010397:Penicillanic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D010878:Piperacillin / Q000627:therapeutic use; D000077725:Piperacillin, Tazobactam Drug Combination; D010949:Plasma; D010956:Plasmapheresis; D013203:Staphylococcal Infections / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D013921:Thrombocytopenia / Q000209:etiology
chemical_list: D000077725:Piperacillin, Tazobactam Drug Combination; D019980:Amoxicillin-Potassium Clavulanate Combination; D010397:Penicillanic Acid; D010878:Piperacillin