Sheehan's syndrome associated with pancytopenia due to marrow aplasia; full recovery with hormone replacement therapy.
We describe a 52-year-old woman with pancytopenia associated with Sheehan's syndrome, whose presenting feature was severe malaise and syncope after a psychological stress. Hormonal replacement therapy alone (with L-thyroxine and prednisolone) produced clinical and full haematological recovery. This is a very rare case of Sheehan's syndrome because the diagnosis was delayed for 27 years after delivery, and it was associated with pancytopenia.
Ozdogan
M
M
Division of Medical Oncology, Akdeniz University Medical School, Antalya, Turkey. mustafa0051@hotmail.com
Yazicioglu
G
G
Karadogan
I
I
Cevikol
C
C
Karayalcin
U
U
Undar
L
L
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000741:Anemia, Aplastic / Q000150:complications* / Q000188:drug therapy; D004417:Dyspnea / Q000209:etiology; D005221:Fatigue / Q000209:etiology; D005260:Female; D020249:Hormone Replacement Therapy / Q000379:methods*; D006801:Humans; D007018:Hypopituitarism / Q000150:complications* / Q000188:drug therapy; D008875:Middle Aged; D010198:Pancytopenia / Q000188:drug therapy / Q000209:etiology*; D011239:Prednisolone / Q000627:therapeutic use; D013315:Stress, Psychological / Q000150:complications*; D013974:Thyroxine / Q000627:therapeutic use; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones; D011239:Prednisolone; D013974:Thyroxine