Effect of orthophen on microlymphocirculation during fever reaction.
Orthophen improved lymph flow during fever reaction via stimulation of contractile activity of the wall and valves in mesenteric lymphatic vessels of rat small intestine. These changes constitute the pathogenetic mechanism for the effect of orthophen during fever.
Aleksandrov
P N
PN
Laboratory for Microcirculation and Hemolymphorheology, Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences.
Mukhutdinova
F I
FI
Tagirova
D R
DR
Mukhutdinov
D A
DA
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D004008:Diclofenac / Q000494:pharmacology*; D005260:Female; D005334:Fever / Q000188:drug therapy* / Q000503:physiopathology*; D008196:Lymph / Q000187:drug effects / Q000502:physiology; D008208:Lymphatic System / Q000187:drug effects* / Q000503:physiopathology; D042601:Lymphatic Vessels / Q000187:drug effects / Q000503:physiopathology; D008297:Male; D051381:Rats
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac