title: Comparison of outcomes in patients with active infective endocarditis with versus without paravalvular abscess and with and without valve replacement.
abstract: In 82 patients with infective endocarditis, including 11 with a perivalvular abscess detected by transesophageal echocardiography, age was a significant predictor of in-hospital mortality (p <0.001). At 3.8-year follow-up, 5 of 7 patients with an abscess who had valve replacement and 2 of 4 patients with an abscess who did not have surgery survived (p = NS); 13 of 22 patients (59%) with no abscess who had valve replacement and 20 of 49 patients (41%) with no abscess who did not have surgery survived (p = NS).
authors.affiliation: Department of Medicine, Cardiology Division, Westchester Medical Center/New York Medical College, Valhalla, New York 10595, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Langiulli
authors.forename: Pierre
authors.initials: P
authors.lastname: Salomon
authors.forename: Wilbert S
authors.initials: WS
authors.lastname: Aronow
authors.forename: John A
authors.initials: JA
authors.lastname: McClung
authors.forename: Robert N
authors.initials: RN
authors.lastname: Belkin
mesh_terms: D000038:Abscess / Q000150:complications / Q000000981:diagnostic imaging / Q000382:microbiology / Q000401:mortality* / Q000628:therapy; D017548:Echocardiography, Transesophageal; D004697:Endocarditis, Bacterial / Q000150:complications / Q000000981:diagnostic imaging / Q000382:microbiology / Q000401:mortality* / Q000628:therapy; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000382:microbiology / Q000401:mortality* / Q000628:therapy; D006350:Heart Valve Prosthesis; D017052:Hospital Mortality; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009518:New York; D016459:Prosthesis-Related Infections / Q000150:complications / Q000000981:diagnostic imaging / Q000382:microbiology / Q000401:mortality* / Q000628:therapy; D016019:Survival Analysis; D016896:Treatment Outcome