title: Characterization of Tn916S, a Tn916-like element containing the tetracycline resistance determinant tet(S).
abstract: We have characterized a transferable tetracycline resistance (Tcr) element from a Streptococcus intermedius isolate. The gene responsible for this resistance was identified by PCR and Southern hybridization as tet(S). Furthermore, the genetic support for this determinant was shown to be a conjugative transposon closely related to Tn916. This element has been designated Tn916S.
authors.affiliation: Division of Infection and Immunity, Eastman Dental Institute for Oral Health Care Sciences, University College London, London WC1X 8LD, United Kingdom.
authors.forename: Holli
authors.initials: H
authors.lastname: Lancaster
authors.forename: Adam P
authors.initials: AP
authors.lastname: Roberts
authors.forename: Raman
authors.initials: R
authors.lastname: Bedi
authors.forename: Michael
authors.initials: M
authors.lastname: Wilson
authors.forename: Peter
authors.initials: P
authors.lastname: Mullany
mesh_terms: D001483:Base Sequence; D003227:Conjugation, Genetic; D004251:DNA Transposable Elements; D008969:Molecular Sequence Data; D034367:Streptococcus intermedius / Q000235:genetics*; D013753:Tetracycline Resistance / Q000235:genetics*
chemical_list: D004251:DNA Transposable Elements