title: Pharmacological management of metastatic boney pain.
abstract: Many malignancies metastasise to the skeleton. This often results in a relatively unique pain process, which dramatically affects a patient's quality of life. With one in three members of the population likely to develop cancer at some stage in their lives, the prevalence of bone metastases is high. Despite the large financial investment on therapies for these patients, treatment is still suboptimal. In this article, the various treatments available are reviewed. Opiates and bisphosphonates, the mainstays in current practise, are covered in detail, and evolving therapies that may shape future management are also discussed.
authors.affiliation: Guys Hospital, Department of Urology, First Floor, Thomas Guy House, St Thomas Street, London SE1 9RT, UK.
authors.forename: Richard P C
authors.initials: RP
authors.lastname: Viney
authors.forename: Dickon
authors.initials: D
authors.lastname: Hayne
authors.forename: Manit
authors.initials: M
authors.lastname: Ayra
authors.forename: Hitendra R H
authors.initials: HR
authors.lastname: Patel
mesh_terms: D001859:Bone Neoplasms / Q000503:physiopathology* / Q000556:secondary*; D002986:Clinical Trials as Topic; D015928:Cognitive Behavioral Therapy / Q000379:methods; D003131:Combined Modality Therapy / Q000379:methods; D017408:Guidelines as Topic; D006694:Holistic Health; D006801:Humans; D007400:Interprofessional Relations; D010146:Pain / Q000150:complications / Q000188:drug therapy*; D059408:Pain Management; D014944:World Health Organization