title: Antiretroviral treatment of maternal HIV infection.
abstract: OBJECTIVE
  One of my pregnant patients tested positive for human immunodeficiency virus. Will HIV therapy put her pregnancy outcome at risk?
  
  
  CONCLUSIONS
  The biggest risk is vertical transmission of HIV to her baby. She should be treated with combination therapy; triple therapy is required to reduce vertical transmission. Zidovudine is not teratogenic in humans, but information on other antiretroviral drugs is incomplete.
authors.affiliation: Hospital for Sick Children, Toronto, Ont.
authors.forename: Haleh
authors.initials: H
authors.lastname: Talaie
authors.forename: Alejandro A
authors.initials: AA
authors.lastname: Nava-Ocampo
authors.forename: Gideon
authors.initials: G
authors.lastname: Koren
mesh_terms: D019380:Anti-HIV Agents / Q000627:therapeutic use*; D002170:Canada; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000517:prevention & control* / Q000635:transmission; D015497:HIV-1; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy* / Q000821:virology*; D012307:Risk Factors; D016387:Women's Health
chemical_list: D019380:Anti-HIV Agents