Accumulation and distribution of polychlorinated dibenzo-p-dioxin, dibenzofuran, and polychlorinated biphenyl congeners in Atlantic salmon (Salmo salar).
Adult Atlantic salmon (Salmo salar) were fed on four diets containing polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) for 30 weeks. Lipid-normalized concentrations showed that all congeners were equally partitioned between whole-fish and fillet samples. Skinned fillet accumulated approximately 30% of the total PCDD/F and PCB content in fish. Accumulation efficiencies in whole fish were 43% for 2,3,7,8-chlorinated dibenzo-p-dioxins and dibenzofurans, 83% for dioxin-like PCBs, and 78% for other PCB congeners. Among PCDD/Fs, tetra- and pentachlorinated congeners were preferentially accumulated in salmon, whereas hepta- and octachlorinated dibenzo-p-dioxins were excreted in the feces. Substitution patterns that were associated with a preferential accumulation of PCBs in salmon included non-ortho substitution and tetrachlorination. Accumulation efficiencies and lipid-normalized biomagnification factors (BMFs) were not influenced by the PCDD/F and PCB concentrations of the diets. Biomagnification (BMF > 1) of tetra- and pentachlorinated dibenzo-p-dioxins and dibenzofurans and of all the PCBs was observed. Differences in the behavior of PCDD/F and PCB congeners resulted in a selective enrichment of the most toxic congeners in salmon.
Isosaari
Pirjo
P
National Public Health Institute, Department of Environmental Health, P.O. Box 95, FIN-70701 Kuopio, Finland. pirjo.isosaari@ktl.fi
Kiviranta
Hannu
H
Lie
Oyvind
O
Lundebye
Anne-Katrine
AK
Ritchie
Gordon
G
Vartiainen
Terttu
T
D000818:Animals; D001267:Atlantic Ocean; D001572:Benzofurans / Q000032:analysis* / Q000633:toxicity; D000072338:Dibenzofurans, Polychlorinated; D004032:Diet; D004785:Environmental Pollutants / Q000378:metabolism* / Q000633:toxicity; D006801:Humans; D008055:Lipids / Q000737:chemistry; D015999:Multivariate Analysis; D011078:Polychlorinated Biphenyls / Q000032:analysis* / Q000633:toxicity; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000032:analysis* / Q000633:toxicity; D020317:Salmo salar; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity
D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D004785:Environmental Pollutants; D008055:Lipids; D000072317:Polychlorinated Dibenzodioxins; D014874:Water Pollutants, Chemical; C023614:dibenzofuran; D011078:Polychlorinated Biphenyls