title: Sacral nerve stimulation for refractory urge symptoms in elderly patients.
abstract: OBJECTIVE
  The presence of an overactive detrusor (OD) is becoming more prevalent in the elderly and may severely influence the social life and activities of daily living in the senior, otherwise healthy, person. There is a marked age-dependent increase in OD above the age of 65 years, which is mainly attributed to dysfunction, with loss of voluntary control, of the micturition reflex and decreased perception of bladder fullness.
  
  
  METHODS
  Herein, we evaluate the outcome of sacral nerve stimulation in five patients aged >65 years derived from a large, multinational, randomized, prospective study.
  
  
  RESULTS
  The effect on symptoms was excellent in two subjects. There was a moderate improvement in another subject and a variable but eventually small effect in the remaining two patients. The results appeared to be more favourable in younger patients.
  
  
  CONCLUSIONS
  Our findings suggest that the outcome of sacral nerve stimulation is more unpredictable in the elderly, a fact that should be considered when counselling the patient. However, it should be remembered that, even for the older, active person, urge incontinence may have a severe impact on quality of life and that the majority of patients treated with an implant will benefit from this treatment.
authors.affiliation: Sahlgrenska University Hospital Göteborg, Gothenburg, Sweden,.
authors.forename: C
authors.initials: C
authors.lastname: Edlund
authors.forename: H E
authors.initials: HE
authors.lastname: Dijkema
authors.forename: M M
authors.initials: MM
authors.lastname: Hassouna
authors.forename: Ph E V
authors.initials: PE
authors.lastname: Van Kerrebroeck
authors.forename: R
authors.initials: R
authors.lastname: Peeker
authors.forename: U
authors.initials: U
authors.lastname: Van den Hombergh
authors.forename: M
authors.initials: M
authors.lastname: Fall
mesh_terms: D000368:Aged; D004599:Electric Stimulation Therapy; D005260:Female; D006801:Humans; D008160:Lumbosacral Plexus; D008297:Male; D015337:Multicenter Studies as Topic; D011446:Prospective Studies; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome; D001750:Urinary Bladder, Neurogenic / Q000503:physiopathology / Q000628:therapy*; D014549:Urinary Incontinence / Q000503:physiopathology / Q000628:therapy*