title: [A case-control study on the relationship between nutrition and gastric cancer in islanders].
abstract: OBJECTIVE
  To study the association between nutritional factors and gastric cancer in islanders.
  
  
  METHODS
  A population-based case-control study on diet and gastric cancer was carried out in Zhoushan islands, China. 103 cases of gastric cancer newly diagnosed in 2001 and 133 controls frequency-matched by age, sex, and islands of residence among residents in Zhoushan were included in the study. Dietary intake was estimated using a constructed food frequency questionnaire. Total calories and 15 nutrients were calculated according to the food composition table and their adjusted odds ratios (OR) and 95% confidence intervals (CI) were estimated by gender using unconditional logistic regression models.
  
  
  RESULTS
  Increased risks of gastric cancer were associated with protein (ORQ4 vs. Q1=10.3; P for linear trend=0.01), saturated fat (ORQ4 vs. Q1=3.24), and cholesterol (ORQ4 vs. Q1=2.76) particularly among males. Among females, carbohydrate was a significant high-risk nutrient (ORQ4 vs. Q1=14.8; P for linear trend=0.024). In both sexes, all cases reported a significantly higher daily intake of natrium mainly from salts than controls. An inversed association with the risk of gastric cancer was seen in vitamin A and vitamin C.
  
  
  CONCLUSIONS
  The findings from this study provided information about the role of specific nutrients in the etiology of gastric cancer. High intakes of protein, saturated fat, cholesterol, sodium and poor intakes of vitamin A and C could increase the risk of gastric cancer.
authors.affiliation: Ningbo Inspection and Quarantine Bureau, Ningbo 315012, China.
authors.forename: Jiong-Liang
authors.initials: JL
authors.lastname: Qiu
authors.forename: Kun
authors.initials: K
authors.lastname: Chen
authors.forename: Xu-Bo
authors.initials: XB
authors.lastname: Wang
authors.forename: Jian-Yue
authors.initials: JY
authors.lastname: Wang
authors.forename: Li-Jun
authors.initials: LJ
authors.lastname: Zhang
authors.forename: Li-Ming
authors.initials: LM
authors.lastname: Shui
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D004032:Diet; D002149:Energy Intake; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009747:Nutritional Physiological Phenomena; D015995:Prevalence; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000453:epidemiology* / Q000209:etiology; D011795:Surveys and Questionnaires