title: Use of the Q-switched 755-nm alexandrite laser to treat recalcitrant pigment after depigmentation therapy for vitiligo.
abstract: BACKGROUND
  In patients with extensive vitiligo, depigmentation therapy is often preferred over attempts to restore skin color. Bleaching creams sometimes fail to permanently depigment the skin, leaving disfiguring pigmented patches. This recalcitrant pigmentation may be treated with Q-switched laser technology.
  
  
  OBJECTIVE
  The objective was use the Q-switched alexandrite laser to treat recalcitrant pigmentation after unsuccessful attempts at total-body depigmentation for vitiligo.
  
  
  METHODS
  We have attempted to destroy the remaining melanin pigmentation in a 68-year-old woman with vitiligo by using selective photothermolysis from a Q-switched alexandrite laser.
  
  
  RESULTS
  Excellent results were achieved after 10 treatment sessions, with no recurrence of pigment after 1 year of follow-up.
  
  
  CONCLUSIONS
  The Q-switched alexandrite laser was used successfully and safely in a vitiligo patient with recalcitrant pigmentation after unsuccessful depigmentation therapy and may prove useful in other such cases.
authors.affiliation: Division of Dermatology and Cutaneous Sciences, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Jaggi
authors.initials: J
authors.lastname: Rao
authors.forename: Richard E
authors.initials: RE
authors.lastname: Fitzpatrick
mesh_terms: D000368:Aged; D001608:Beryllium; D005260:Female; D006801:Humans; D053685:Laser Therapy; D010859:Pigmentation Disorders / Q000532:radiotherapy*; D014820:Vitiligo / Q000628:therapy*
chemical_list: C112654:alexandrite; D001608:Beryllium