title: MooPoong (Gye Young Jeong) increases HDL-cholesterol but decreases LDL cholesterol and body-weight.
abstract: MooPoong (MP, Gye Young Jeong), a Korean traditional wine, has been used as a prevention and treatment agent of blood circulatory trouble. To evaluate such an effect of MP, we analyzed whether the plasma levels of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and body weight change after rats were fed on high fat diet with MP for 8 weeks. Plasma LDL cholesterol level decreased by 5.6% in 0.128% MP treated group and by 11.1% in 0.640% MP treated group. However, HDL cholesterol was increased by 6.7% in 0.128% MP diet group and 33.3% in 0.640% MP diet group. In addition, there was a significant weight loss in the MP treated group compared with the high-fat diet group (P < 0.05). Our findings indicate that MP may contain compounds with actions which can treat blood circulatory trouble as well as overweight.
authors.affiliation: Department of Pharmacology, College of Oriental Medicine, Kyung Hee University, Dongdaemun-Gu, Seoul, Republic of Korea.
authors.forename: Hwan-Suck
authors.initials: HS
authors.lastname: Chung
authors.forename: Seung-Heon
authors.initials: SH
authors.lastname: Hong
authors.forename: Keum-Rok
authors.initials: KR
authors.lastname: Do
authors.forename: Hyung-Koo
authors.initials: HK
authors.lastname: Rhee
authors.forename: Sung-Ki
authors.initials: SK
authors.lastname: Jung
authors.forename: Woo-Jun
authors.initials: WJ
authors.lastname: Hwang
authors.forename: Hyung-Min
authors.initials: HM
authors.lastname: Kim
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001835:Body Weight; D008076:Cholesterol, HDL / Q000097:blood*; D008078:Cholesterol, LDL / Q000097:blood*; D004041:Dietary Fats / Q000008:administration & dosage; D007723:Korea; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D015430:Weight Gain; D014920:Wine
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D004041:Dietary Fats; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase