Epidermal naevus syndrome (Solomon's syndrome) associated with bladder cancer in a 20-year-old female.
Epidermal naevus syndrome was first described by Solomon et al. in 1968, based on a study of 12 patients. Herein we report the case of a 20-year-old female diagnosed with epidermal naevus syndrome at the age of 3 years. Subsequently she experienced several different symptoms and at the last exploration a suspicious lesion was found in her bladder. The definitive pathology diagnosis was transitional cell carcinoma of the bladder, which is extremely rare in patients aged <21 years. It seems that this neoplastic lesion was directly related to the essential pathology of the patient, namely epidermal naevus syndrome.
García de Jalón
Angel
A
Service of Urology, Miguel Servet University Hospital, Zaragoza, Spain.
Azúa-Romeo
Javier
J
Trivez
Miguel Angel
MA
Pascual
Daniel
D
Blas
Miguel
M
Rioja
Luis Angel
LA
D000328:Adult; D001707:Biopsy, Needle; D002295:Carcinoma, Transitional Cell / Q000473:pathology* / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D015653:Cystectomy / Q000379:methods; D003558:Cystoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D016609:Neoplasms, Second Primary / Q000473:pathology* / Q000628:therapy; D018330:Nevus, Intradermal / Q000473:pathology* / Q000628:therapy; D018570:Risk Assessment; D012878:Skin Neoplasms / Q000473:pathology* / Q000628:therapy; D013577:Syndrome; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000628:therapy