An evaluation of cognitive behavioral therapy as a treatment for dissociative seizures: a pilot study.
OBJECTIVE
To evaluate in an open trial the effectiveness of cognitive behavioral therapy as a treatment of adults with dissociative seizures (i.e., "pseudoseizures").


BACKGROUND
Although suggestions have been made concerning the management of patients with dissociative seizures, no studies have previously evaluated the systematic use of cognitive behavioral therapy in the treatment of this disorder.


METHODS
Twenty patients diagnosed with dissociative seizures were offered treatment comprising 12 sessions of cognitive behavioral therapy. Principal outcome measures were dissociative seizure frequency and psychosocial functioning, including improvement in employment status and mood. Measures were administered before treatment, at the end of treatment, and at a 6-month follow-up.


RESULTS
Treatment was completed by 16 patients (questionnaire measures were not available for 4 patients who discontinued treatment). Following treatment, there was a highly significant reduction in seizure frequency and an improvement in self-rated psychosocial functioning. These improvements were maintained at the 6-month follow-up. There was also a tendency for patients to have improved their employment status between the start of treatment and the 6-month follow-up period.


CONCLUSIONS
In this open prospective trial, cognitive behavioral therapy was associated with a reduction in dissociative seizure frequency and an improvement in psychosocial functioning in adults with dissociative seizures.
Goldstein
Laura H
LH
Department of Psychology, Institute of Psychiatry, De Crespigny Park, London. l.goldstein@iop.kcl.ac.uk
Deale
Alicia C
AC
Mitchell-O'Malley
Sara J
SJ
Toone
Brian K
BK
Mellers
John D C
JD
D000328:Adult; D015928:Cognitive Behavioral Therapy; D004213:Dissociative Disorders / Q000150:complications / Q000523:psychology / Q000628:therapy*; D004651:Employment; D005260:Female; D006801:Humans; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D012640:Seizures / Q000523:psychology* / Q000628:therapy*; D012919:Social Behavior; D016896:Treatment Outcome