The evaluation of small fiber function-autonomic and quantitative sensory testing.
Disorders of the autonomic and small nerve fibers comprise a wide spectrum of disease states that cross a multitude of clinical specialties.The evaluation of these disorders allows the investigator to determine the presence or absence of abnormalities in the lightly myelinated and unmyelinated nerve fibers with minimal discomfort to the patient. The severity of dysfunction also can be determined to guide therapy and aid in prognostication for individual patients.
Gibbons
Christopher
C
Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Freeman
Roy
R
D001341:Autonomic Nervous System / Q000503:physiopathology*; D001342:Autonomic Nervous System Diseases / Q000175:diagnosis* / Q000503:physiopathology; D001833:Body Temperature Regulation / Q000502:physiology; D002319:Cardiovascular System / Q000294:innervation; D005712:Galvanic Skin Response / Q000502:physiology; D006801:Humans; D009412:Nerve Fibers / Q000502:physiology*; D009468:Neuromuscular Diseases / Q000175:diagnosis* / Q000503:physiopathology; D012016:Reference Values; D011984:Sensory Receptor Cells / Q000503:physiopathology*; D012684:Sensory Thresholds / Q000502:physiology; D012881:Skin Temperature / Q000502:physiology; D018667:Tilt-Table Test; D014636:Valsalva Maneuver / Q000502:physiology