[Study on the afficacy of hepatitis B immunization among youngsters in Beijing].
OBJECTIVE
To evaluating the epidemiological effect after hepatitis B immunization among youngsters in Beijing.


METHODS
A multistage sampling method was used for data collection from immunization cards, reports on field epidemiological survey on hepatitis B virus (HBV) immunization of youngsters and the analysis of infectious diseases. HBsAg, anti-HBs and anti-HBc levels were detected by solid phase radioimmunoassays (SPRIA).


RESULTS
The average incidence rates of hepatitis B in 10 - 19 years-olds prior to HBV immunization was 12.11-16.89/100 000, while declined to 1.78-10.95/100 000 (chi(2) = 10.71 - 60.45, P < 0.01). HBsAg carrying rate of the youngsters decreased from 6.34% to 1.37% (80.00%) after vaccination (chi(2) = 14.16, P < 0.01).


CONCLUSIONS
Hepatitis B vaccination among youngsters is an effective measure for the prevention and control of hepatitis B virus infection.
Gong
Xiao-hong
XH
Department of Infectious and Endemic Diseases Control, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
Li
Yang-hua
YH
Liu
Li-rong
LR
Jia
Lei
L
Xing
Yu-lan
YL
Wang
Yu-qin
YQ
D000293:Adolescent; D002648:Child; D002681:China / Q000453:epidemiology; D006509:Hepatitis B / Q000453:epidemiology / Q000517:prevention & control*; D017325:Hepatitis B Vaccines / Q000276:immunology; D006801:Humans; D007115:Immunization Schedule; D015995:Prevalence; D014611:Vaccination; D014614:Vaccines, Synthetic / Q000276:immunology
D017325:Hepatitis B Vaccines; D014614:Vaccines, Synthetic