Research on prevention of bilirubin-induced brain injury and kernicterus: National Institute of Child Health and Human Development conference executive summary. 2003.
In July 2003, the National Institute of Child Health and Human Development convened a conference, "Research on Prevention of Bilirubin-Induced Brain Injury and Kernicterus: Bench-to-Bedside." This article will provide a summary of presentations and discussions from this conference. The summary will focus on the identified knowledge gaps in 5 areas related to bilirubin-induced brain injury and kernicterus: 1) neurobiology and neuroimaging; 2) epidemiology and issues of clinical management; 3) methodologies for assessing clinical jaundice and direct and noninvasive measurement of serum bilirubin and hemolysis; 4) therapies for management of neonatal hyperbilirubinemia; and 5) public health surveillance and systems-based approaches to prevention.
Blackmon
Lillian R
LR
University of Maryland School of Medicine, Baltimore, Maryland, USA.
Fanaroff
Avroy A
AA
Raju
Tonse N K
TN
D001663:Bilirubin / Q000097:blood; D035843:Biomedical Research / Q000592:standards; D006461:Hemolysis; D006801:Humans; D007231:Infant, Newborn; D007567:Jaundice, Neonatal / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D007647:Kernicterus / Q000175:diagnosis / Q000517:prevention & control*; D011159:Population Surveillance
D001663:Bilirubin