Cardiovascular responsiveness to brief cognitive challenges and pain sensitivity in women.
The primary purpose of the study was to determine the relationship between cardiovascular (CV) responsiveness to brief cognitive tasks and pain sensitivity in normotensive individuals. Fifty-eight healthy women without a history of chronic pain were exposed to three laboratory tasks (reading aloud, speech task, and tracking task) and repeated pain testing (electrocutaneous and pressure pain stimulation) while mean arterial pressure (MAP) and heart rate (HR) were continuously recorded. Generally, subjects with higher HR responsiveness to the cognitive tasks displayed a reduced pain sensitivity, particularly to electrocutaneous pain stimulation. Moreover, the two types of pain stimulation seemed to trigger somewhat different CV response patterns. Inclusion of pain-related CV changes as control variables affected the relationship between HR responsiveness and pain sensitivity, although differently for electrocutaneous and pressure pain. However, inclusion of psychological control variables had no significant effects. Although relatively large CV changes were observed during the experimental tasks, small and insignificant changes in simultaneous or subsequent electrocutaneous pain sensitivity occurred. However, significant increases in pressure pain threshold and tolerance occurred after the speech task, during which MAP level was at its highest. The present findings support the hypothesis that pain sensitivity and CV response share a common mechanism, which, however, is not necessarily linked to either elevated blood pressure levels or other risk factors for hypertension.
Vassend
Olav
O
Dental Faculty, University of Oslo, Blindern, Oslo, Norway. ovassend@odont.uio.no
Knardahl
Stein
S
D000223:Adaptation, Psychological; D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D002320:Cardiovascular Physiological Phenomena; D003071:Cognition / Q000502:physiology*; D004558:Electric Stimulation / Q000009:adverse effects; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007807:Language Tests; D009483:Neuropsychological Tests; D010146:Pain / Q000209:etiology / Q000503:physiopathology* / Q000523:psychology*; D010147:Pain Measurement; D017288:Pain Threshold / Q000502:physiology*; D011312:Pressure / Q000009:adverse effects; D012018:Reflex / Q000502:physiology; D012307:Risk Factors; D012737:Sex Factors