Bone relapse in acute lymphoblastic leukemia.
Acute lymphoblastic leukemia (ALL) can occasionally relapse in unusual extramedullary sites like bone. Here we present a 6.5-year old boy with 'T' cell ALL who developed a swelling in left tibia which was infiltrated with lymphoblasts 7 months after completion of chemotherapy. Bone marrow and cerebrospinal fluid were negative for blasts. This is the first reported case of bone relapse in ALL from India. We discuss the previous cases of isolated bone relapse in ALL reported in English literature.
Padmanjali
K S
KS
Departments of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Bakhshi
Sameer
S
Thavaraj
Vasantha
V
Karak
A K
AK
Arya
L S
LS
D001842:Bone and Bones / Q000473:pathology; D002675:Child, Preschool; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology*; D012008:Recurrence; D013977:Tibia / Q000473:pathology*