[A case of heterochronous liver metastasis of gastric cancer favorably responding to TS-1].
We report herein a case of heterochronous hepatic metastasis of gastric cancer that responded well to chemotherapy using TS-1. The patient was a 72-year-old man who underwent total gastrectomy for gastric cancer. Liver metastasis (S8, 4 cm in diameter) was found 3 months after surgery. TS-1 (100 mg/day) was administered orally everyday for a total of 33 weeks, after which the liver metastasis showed CR. Grade 2 fever and grade 2 dermatitis were the only adverse reactions observed, and the patient did not require hospitalization by discontinuing TS-1 administration. The present case suggests the usefulness of chemotherapy using TS-1.
Tokuhara
Takaya
T
Dept. of Gastroenterological and General Surgery, Saiseikai Suita Hospital.
Hara
Akinori
A
Takahashi
Yuko
Y
Harada
Tomoaki
T
Izumi
Nobuyuki
N
Iwamoto
Shinji
S
Satake
Kazunari
K
D000284:Administration, Oral; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008207:Lymphatic Metastasis; D008297:Male; D010094:Oxonic Acid / Q000627:therapeutic use*; D011184:Postoperative Period; D011725:Pyridines / Q000627:therapeutic use*; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D005641:Tegafur / Q000627:therapeutic use*
D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid