Erythroleukemia: a clinco-hematological review of four cases.
Erythroleukemia is an uncommon disorder in children. Four cases of pediatric erythroleukemia, diagnosed over a period of nine years are presented. The patients presented with pallor, fever and hepatosplenomegaly of recent onset. Peripheral smear examination showed anemia, thrombocytopenia and circulating blasts. The bone marrow displayed erythroid hyperplasia with dysplasia and PAS positive erythroblasts. Myeloid blasts were myeloperoxidase positive and one case showed positivity for non specific esterase, indicating monocytoid differentiation, a poor prognostic feature. Prognosis was poor and follow up period was short.
Batra
Vineeta Vijay
VV
Department of Hematology, All India Institute of Medical Sciences, New Delhi, India.
Karan
Akhilesh S
AS
Saxena
Renu
R
D002648:Child; D005260:Female; D006403:Hematologic Tests; D006801:Humans; D004915:Leukemia, Erythroblastic, Acute / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism*; D008297:Male