Accelerated asymmetric transfer hydrogenation of aromatic ketones in water.
Asymmetric transfer hydrogenation of various simple aromatic ketones by the Ru-TsDPEN catalyst was shown to be feasible in aqueous HCOONa without calling for any catalyst modification, furnishing ee's of up to 95% and significantly faster rates than in the HCOOH-NEt(3) azeotrope.
Wu
Xiaofeng
X
Liverpool Centre for Materials and Catalysis, Department of Chemistry, University of Liverpool, Liverpool, UKL69 7ZD.
Li
Xiaoguang
X
Hems
William
W
King
Frank
F
Xiao
Jianliang
J