A new ecdysteroid with unique 9beta-OH and four other ecdysteroids from Silene italica ssp. nemoralis.
A new natural ecdysteroid, 9beta,20-dihydroxyecdysone (1) and four related compounds 5alpha-20-hydroxyecdysone (2), 5alpha-2-deoxy-integristerone A (3), integristerone A (4) and 22-deoxy-integristerone A (5) were isolated from the herb of Silene italica ssp. nemoralis. Compound 1 is the C-9 epimer of the known 9alpha,20-dihydroxyecdysone (6) and represents a peculiar steroid skeleton. The structures of the compounds were elucidated by 1D and 2D NMR, IR and MS spectroscopy.
Simon
András
A
Institute for General and Analytical Chemistry, Budapest University of Technology and Economics, Budapest, Szt. Gellért tér 4, H-1111 Hungary.
Pongrácz
Zita
Z
Tóth
Gábor
G
Mák
Marianna
M
Máthé
Imre
I
Báthori
Mária
M
D026461:Ecdysteroids / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000302:isolation & purification; D008968:Molecular Conformation; D029751:Silene / Q000737:chemistry*
D026461:Ecdysteroids