Structural analysis of 1-aminocyclopropane-1-carboxylate deaminase: observation of an aminyl intermediate and identification of Tyr 294 as the active-site nucleophile.
Karthikeyan
Subramanian
S
Division of Medicinal Chemistry, College of Pharmacy and Department of Chemistry and Biochemistry, University of Texas, Austin, TX 78712, USA.
Zhao
Zongbao
Z
Kao
Chai-Lin
CL
Zhou
Qingxian
Q
Tao
Zhihua
Z
Zhang
Hong
H
Liu
Hung-Wen
HW
D001665:Binding Sites; D019755:Carbon-Carbon Lyases / Q000737:chemistry*; D008958:Models, Molecular; D017354:Point Mutation; D011549:Pseudomonas / Q000201:enzymology; D013237:Stereoisomerism; D014443:Tyrosine / Q000737:chemistry*
D014443:Tyrosine; C033634:1-aminocyclopropane-1-carboxylate deaminase; D019755:Carbon-Carbon Lyases