Safety of conventional drugs and biologic agents for Rheumatoid Arthritis.
While initial researches documented that Rheumatoid Arthritis (RA) patients who took biologic agents had decreased symptoms with those receiving traditional treatment, safety of the drugs remains a concern. The authors in this paper review the safety of the RA new therapeutic approach utilizing biological agents and compare it with the safety of conventional disease-modifying anti-rheumatic drugs (DMARDs).
Amoroso
A
A
Dpt. of Clinical Medicine, University of Rome La Sapienza, Italy.
Gigante
A
A
Gianni
C
C
Amoroso
D
D
Zennaro
D
D
Galluzzo
S
S
Caccavo
D
D
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000503:physiopathology; D017326:Clinical Trials, Phase III as Topic; D006801:Humans; D007155:Immunologic Factors / Q000009:adverse effects* / Q000627:therapeutic use; D011358:Product Surveillance, Postmarketing / Q000379:methods; D016032:Randomized Controlled Trials as Topic; D012189:Retrospective Studies
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007155:Immunologic Factors