Indium mediated allylation of glyoxylate oxime ethers, esters and cyanoformates.
An indium mediated procedure has been developed for the allylation of activated O-functionalised oximes and nitriles as exemplified by a variety of glyoxylate derivatives. This method gives the corresponding free (or protected) amine in a one pot-process. The method is regiospecific and is carried out under remarkably mild conditions so that even oxime esters can be subjected to the typical reaction conditions.
Ritson
Dougal J
DJ
School of Chemistry, University of Bristol, Cantock's Close, Bristol, UKBS8 1TS. r.j.cox@bris.ac.uk
Cox
Russell J
RJ
Berge
John
J