Hepatitis A outbreaks--methods of intervention in South-East Asian countries.
BACKGROUND
In many Asian countries, improved hygiene standards and socio-economic conditions have led to a reduction in exposure to the hepatitis A virus (HAV) in childhood. However, the persistence of circulating HAV may lead to hepatitis A outbreaks, particularly in adolescents and adults. In other countries and specific areas, where socio-economic conditions have not improved as markedly, HAV endemicity remains medium-to-high. A systematic approach to outbreak control is therefore urgently needed.


METHODS
The Steering Committee for Prevention and Control of Infectious Diseases reviewed reports on recent hepatitis A outbreaks in South-East Asian countries and determined that there is no systematic regional plan for the containment of such outbreaks. By contrast, on reviewing reports on outbreaks in several North American and European countries, it was found that the most important elements of successful outbreak control are a plan of action, rapid and widespread communication, public education and vaccination of household contacts to prevent secondary cases.


RESULTS
This investigation proposes an outbreak control programme consisting of six key stages -- initiation, planning, set-up, implementation, vaccination of at-risk populations and evaluation. Outbreak control requires the formation of an outbreak management team, plus a task force to implement intervention and educate the public. The vaccination of family members and close contacts is a central element of the programme.


CONCLUSIONS
This model programme for hepatitis A outbreak control provides a framework for action in countries and specific areas where the disease remains a problem.
David
Annette M
AM
College of Medicine, University of the Philippines, Manila, Philippines. amdavid@ite.net
D001210:Asia, Southeastern / Q000453:epidemiology; D004196:Disease Outbreaks / Q000517:prevention & control*; D006506:Hepatitis A / Q000453:epidemiology / Q000517:prevention & control* / Q000821:virology; D022362:Hepatitis A Vaccines; D017957:Hepatitis A Virus, Human / Q000254:growth & development*; D006801:Humans; D017589:Immunization Programs; D015994:Incidence; D014611:Vaccination
D022362:Hepatitis A Vaccines