title: Resting energy expenditure in uremic, diabetic, and uremic diabetic subjects.
abstract: We compared Harris and Benedict [H & B; Harris, J. A., & Benedict, F. G. (1919). A biometric study of basal metabolism in man. Washington, DC: Carnegie Institution of Washington. p. 279.] predicted resting energy expenditure (REE) to values measured by indirect calorimetry in normal, uremic, diabetic, and uremic diabetic subjects. Predicted REE were overestimated (+9.2%, P<.005) in uremic subjects, and underestimated (-8.5%, P<.0001) in diabetic subjects. Uremic diabetic subjects were submitted to the opposite influences of diabetes and uremia on REE. Differences in body composition (lower fat-free mass in uremia and higher fat-free mass in diabetes) played a major role in these influences. In uremic diabetic subjects, predicted REE seemed well fitted to measured REE (biases <2%), but they were less correlated, and limits of agreement between predicted and measured REE were large. Although their mean REE seems normal, prediction by the H&B equation leads to important individual errors in uremic diabetic subjects: direct measurement of energy expenditure by indirect calorimetry may be helpful to precise the adequate energy content of a diet for these subjects.
authors.affiliation: Nutrition-Diabétologie, Hopital Haut-Lévêque, Avenue de Magellan, 33600 Pessac, France. vincent.rigalleau@wanadoo.fr
authors.forename: V
authors.initials: V
authors.lastname: Rigalleau
authors.forename: C
authors.initials: C
authors.lastname: Lasseur
authors.forename: S
authors.initials: S
authors.lastname: Pécheur
authors.forename: P
authors.initials: P
authors.lastname: Chauveau
authors.forename: C
authors.initials: C
authors.lastname: Combe
authors.forename: C
authors.initials: C
authors.lastname: Perlemoine
authors.forename: L
authors.initials: L
authors.lastname: Baillet
authors.forename: H
authors.initials: H
authors.lastname: Gin
mesh_terms: D000328:Adult; D000368:Aged; D001823:Body Composition; D015992:Body Mass Index; D048909:Diabetes Complications / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000378:metabolism*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000378:metabolism; D004734:Energy Metabolism; D005260:Female; D005919:Glomerular Filtration Rate; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D012146:Rest; D014511:Uremia / Q000150:complications* / Q000378:metabolism*
chemical_list: D006442:Glycated Hemoglobin