title: Health care utilisation of prematurely born, preschool children related to hospitalisation for RSV infection.
abstract: BACKGROUND
  In prematurely born infants with chronic lung disease (CLD), RSV hospitalisation is associated with increased health service utilisation and costs in the first two years after birth.
  
  
  OBJECTIVE
  To determine whether RSV hospitalisation in the first two years was associated with chronic respiratory morbidity during the preschool years in prematurely born children who had had CLD.
  
  
  METHODS
  Retrospective review of readmissions, outpatient attendances, and community care in years 2-4 and, at age 5 years, assessment of the children's respiratory status and their health related quality of life. Comparison was made of the results of children who had had at least one hospitalisation in the first two years after birth for RSV infection (RSV group) to those of the rest of the cohort. Participants were 190 of an original cohort of 235 infants with CLD and a median gestational age 27 (range 22-33) weeks.
  
  
  RESULTS
  The 33 children in the RSV group, compared to the rest of the cohort, had a greater duration of hospital stay and more outpatient appointments. The RSV group had required more prescriptions for all treatments and respiratory medications, and more had used an inhaler. The cost of care of the RSV group was higher (median 2630 pounds sterling [4000 Euros, US4800 dollars], range 124-18,091 pounds sterling versus 1360 pounds sterling [2500 Euros, US3000 dollars], range 5-18 929 pounds sterling ) and their health related quality of life was lower.
  
  
  CONCLUSIONS
  In prematurely born children who had developed CLD, RSV hospitalisation in the first two years was associated with chronic respiratory morbidity and increased cost of care.
authors.affiliation: Dept of Child Health, King's College Hospital, London SE5 9RS, UK. anne.greenough@kcl.ac.uk
authors.forename: A
authors.initials: A
authors.lastname: Greenough
authors.forename: J
authors.initials: J
authors.lastname: Alexander
authors.forename: S
authors.initials: S
authors.lastname: Burgess
authors.forename: J
authors.initials: J
authors.lastname: Bytham
authors.forename: P A J
authors.initials: PA
authors.lastname: Chetcuti
authors.forename: J
authors.initials: J
authors.lastname: Hagan
authors.forename: W
authors.initials: W
authors.lastname: Lenney
authors.forename: S
authors.initials: S
authors.lastname: Melville
authors.forename: N J
authors.initials: NJ
authors.lastname: Shaw
authors.forename: J
authors.initials: J
authors.lastname: Boorman
authors.forename: S
authors.initials: S
authors.lastname: Coles
authors.forename: J
authors.initials: J
authors.lastname: Turner
authors.forename: F
authors.initials: F
authors.lastname: Pang
mesh_terms: D000553:Ambulatory Care / Q000191:economics; D002675:Child, Preschool; D003365:Costs and Cost Analysis / Q000191:economics; D006760:Hospitalization / Q000191:economics*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D015931:Intensive Care, Neonatal / Q000191:economics; D007902:Length of Stay / Q000191:economics; D010342:Patient Acceptance of Health Care; D010359:Patient Readmission / Q000191:economics; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications* / Q000191:economics; D012120:Respiration Disorders / Q000191:economics; D018357:Respiratory Syncytial Virus Infections / Q000150:complications* / Q000191:economics; D012189:Retrospective Studies; D012307:Risk Factors