title: [Clinical analysis of 15 cases of Paget's disease of the scrotum].
abstract: OBJECTIVE
  To study the clinicopathologic features and treatment of Paget's disease of the scrotum.
  
  
  METHODS
  Fifteen cases of Paget's disease of the scrotum, pathologically diagnosed and successfully treated by surgery from 1987 to 2003, were studied retrospectively.
  
  
  RESULTS
  Typical pathological features were observed in all the patients. Thirteen cases were followed up for 0. 5 approximately 13 years, of whom 1 case relapsed within 3 years, 2 died of metastasis after 2 years, and 3 died of cardiovascular diseases, with no recurrence in the others.
  
  
  CONCLUSIONS
  Early biopsy and extensive excision of the scrotal lesion is the first choice of treatment for Paget's disease, with good operative effect and satisfactory prognosis. A 2nd operation could be considered for patients of local relapse.
authors.affiliation: Department of Urology, First Affiliated Hospital, Zhejiang University Medical College, Hangzhou, Zhejiang 310003, China. shen_bh@sina.com
authors.forename: Baihua
authors.initials: B
authors.lastname: Shen
authors.forename: Hongzhou
authors.initials: H
authors.lastname: Meng
authors.forename: Liping
authors.initials: L
authors.lastname: Xie
authors.forename: Songliang
authors.initials: S
authors.lastname: Cai
authors.forename: Shuo
authors.initials: S
authors.lastname: Wang
authors.forename: Zhigen
authors.initials: Z
authors.lastname: Zhang
authors.forename: Yimin
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005834:Genital Neoplasms, Male / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D010145:Paget Disease, Extramammary / Q000473:pathology* / Q000601:surgery; D012189:Retrospective Studies; D012611:Scrotum / Q000473:pathology*