title: The molecular basis of insecticide resistance in mosquitoes.
abstract: Insecticide resistance is an inherited characteristic involving changes in one or more insect gene. The molecular basis of these changes are only now being fully determined, aided by the availability of the Drosophila melanogaster and Anopheles gambiae genome sequences. This paper reviews what is currently known about insecticide resistance conferred by metabolic or target site changes in mosquitoes.
authors.affiliation: Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK. hemingway@liv.ac.uk
authors.forename: Janet
authors.initials: J
authors.lastname: Hemingway
authors.forename: Nicola J
authors.initials: NJ
authors.lastname: Hawkes
authors.forename: Lynn
authors.initials: L
authors.lastname: McCarroll
authors.forename: Hilary
authors.initials: H
authors.lastname: Ranson
mesh_terms: D000818:Animals; D000852:Anopheles / Q000235:genetics*; D009033:Culicidae / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics; D006793:Houseflies / Q000235:genetics; D015222:Sodium Channels / Q000235:genetics
chemical_list: D015222:Sodium Channels