Subclinical hyperthyroidism: to treat or not to treat?
Subclinical hyperthyroidism may be defined as the presence of free thyroxine and tri-iodothyronine levels within the reference range and a reduced serum thyroid stimulating hormone (TSH) level. In this review the prevalence of low TSH in the population and health consequences of subclinical hyperthyroidism, for example, effects on heart and bone mass, are discussed. Guidelines for treatment are given, based on expert opinion.
Hoogendoorn
E H
EH
Department of Endocrinology, University Medical Center Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands. e.hoogendoorn@endo.umcn.nl
den Heijer
M
M
van Dijk
A P J
AP
Hermus
A R
AR
D015519:Bone Density; D003704:Dementia / Q000209:etiology; D006331:Heart Diseases / Q000209:etiology; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications / Q000628:therapy*; D019964:Mood Disorders / Q000209:etiology; D017410:Practice Guidelines as Topic; D011788:Quality of Life