title: Intramolecular iron-mediated diene/olefin cyclocoupling: formation of carbon spirocycles.
abstract: [reaction: see text] A short and convenient diastereoselective synthesis of all-carbon spirocylic molecules was developed. A straightforward protocol that involves rearrangement of the diene-Fe(CO)(3) complex followed by cyclization delivers the desired product. The reaction substrates were easily prepared by reaction of an appropriate nucleophile and a cyclohexadienyl-Fe(CO)(3) cation.
authors.affiliation: Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA. ajp4@case.edu
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Pearson
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Wang
authors.forename: Ismet B
authors.initials: IB
authors.lastname: Dorange
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D004224:Diterpenes / Q000737:chemistry; D007501:Iron / Q000737:chemistry*; D000081223:Polycyclic Sesquiterpenes; D013141:Spiro Compounds / Q000138:chemical synthesis*; D013237:Stereoisomerism; D013729:Terpenes / Q000737:chemistry
chemical_list: D000475:Alkenes; D004224:Diterpenes; D000081223:Polycyclic Sesquiterpenes; D013141:Spiro Compounds; D013729:Terpenes; C474511:elisabethin A; C078669:cedrol; D007501:Iron