title: SOFA score predicts postoperative outcome of patients with colorectal perforation.
abstract: OBJECTIVE
  Colorectal perforation remains a life-threatening condition associated with high mortality. Various factors and operative procedures have been discussed in regard to prediction of outcome, and several scoring systems have been proposed to predict the outcome of critically ill patients. The present study was undertaken to identify factors and determine predictive scoring systems for the postoperative outcome of patients with colorectal perforation.
  
  
  METHODS
  Between January 1996 and December 2000, 45 consecutive patients underwent emergency operation for colorectal perforation. Twelve patients (26.7%) died in hospital. The correlation of outcome with various preoperative factors, APACHE II and SOFA scores were assessed retrospectively.
  
  
  RESULTS
  Univariate analysis showed that outcome was significantly related to maximum SOFA score (p=0.0069). Multivariate logistic regression analysis demonstrated that the maximum SOFA score was an independent predictor (p=0.016). Serum creatinine level (p=0.013) and platelet count (p=0.036) were associated with patient outcome in the SOFA score. Patients with a SOFA score higher than 7 had a greater risk of hospital death (p=0.0085).
  
  
  CONCLUSIONS
  The maximum postoperative SOFA score is a useful predictor of the outcome from surgery for colorectal perforation.
authors.affiliation: Department of Surgery, Tokyo Medical and Dental University, Tokyo, Japan. t.ochiai.msrg@tmd.ac.jp
authors.forename: Takanori
authors.initials: T
authors.lastname: Ochiai
authors.forename: Susumu
authors.initials: S
authors.lastname: Hiranuma
authors.forename: Noriaki
authors.initials: N
authors.lastname: Takiguchi
authors.forename: Koji
authors.initials: K
authors.lastname: Ito
authors.forename: Atsuhiro
authors.initials: A
authors.lastname: Kawaguchi
authors.forename: Takehisa
authors.initials: T
authors.lastname: Iwai
authors.forename: Shigeki
authors.initials: S
authors.lastname: Arii
mesh_terms: D018806:APACHE; D003404:Creatinine / Q000097:blood; D004638:Emergency Treatment; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007416:Intestinal Perforation / Q000097:blood / Q000401:mortality / Q000601:surgery*; D008297:Male; D015999:Multivariate Analysis; D010976:Platelet Count; D011379:Prognosis; D012372:ROC Curve; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D003404:Creatinine