Detection of bcl-2 rearrangement in mucosa-associated lymphoid tissue lymphomas from patients with hepatitis C virus infection.
It has been shown that t(14;18)(q32;q21) involving fusion of IGH with MALT1 occurs frequently in mucosa-associated lymphoid tissue (MALT) lymphomas. Results of the present study indicate that the classical form of t(14;18)(q32;q21) involving fusion of IGH with bcl-2 can be detectable in a subset of MALT lymphomas in patients with hepatitis C virus (HCV) infection.
Libra
Massimo
M
De Re
Valli
V
Gloghini
Annunziata
A
Gasparotto
Daniela
D
Gragnani
Laura
L
Navolanic
Patrick M
PM
De Vita
Salvatore
S
Mazzarino
Maria Clorinda
MC
Zignego
Anna Linda
AL
Carbone
Antonino
A
Boiocchi
Mauro
M
D000328:Adult; D000368:Aged; D005260:Female; D015322:Gene Rearrangement, B-Lymphocyte; D019254:Genes, bcl-2 / Q000235:genetics*; D006526:Hepatitis C / Q000150:complications / Q000235:genetics*; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000235:genetics* / Q000821:virology*; D008297:Male; D008875:Middle Aged