Successful pregnancy after vaginal cancer treated with interferon.
A 25-year-old white woman with a vaginal invasive epidermal carcinoma was treated with interferon-alpha 2b (3,000,000 U intralesional, every two days for a total of 18 applications). Follow-up with Papanicolaou and colposcopy showed complete regression of the vaginal lesion, After three years the patient got pregnant. The prenatal course was uneventful and a vaginal delivery was performed. She is currently in follow-up without any signs of recurrence.
Murta
Eddie Fernando Candido
EF
Discipline of Gynecology and Obstetrics, Faculty of Medicine of Triângulo Mineiro, Uberaba, MG, Brazil. eddiemurta@mednet.com.br
Tavares Murta
Beatriz Martins
BM
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000601:surgery; D003127:Colposcopy; D004598:Electrosurgery; D005260:Female; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D065006:Papanicolaou Test; D011247:Pregnancy; D011256:Pregnancy Outcome; D011994:Recombinant Proteins; D016896:Treatment Outcome; D014625:Vaginal Neoplasms / Q000188:drug therapy* / Q000601:surgery; D014626:Vaginal Smears; D002578:Uterine Cervical Dysplasia / Q000188:drug therapy* / Q000601:surgery
D000970:Antineoplastic Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins