title: The molecular basis of beta-thalassemia in Argentina. Influence of the pattern of immigration from the Mediterranean Basin.
abstract: In order to determine the molecular heterogeneity of the beta-thalassemia gene and to analyze the influence of immigration from the Mediterranean Basin, a total of 254 families (475 subjects) from Argentinean beta-thalassemia patients were investigated using molecular biology techniques. This allowed us to provide a simplified diagnosis and genetic counselling of this disorder in Argentina.
authors.forename: Liliana C
authors.initials: LC
authors.lastname: Rossetti
authors.forename: Héctor M
authors.initials: HM
authors.lastname: Targovnik
authors.forename: Viviana
authors.initials: V
authors.lastname: Varela
mesh_terms: D001118:Argentina / Q000453:epidemiology / Q000208:ethnology; D004641:Emigration and Immigration; D005060:Europe / Q000208:ethnology; D005192:Family Health; D006801:Humans; D017720:Molecular Epidemiology; D017354:Point Mutation; D017086:beta-Thalassemia / Q000453:epidemiology / Q000208:ethnology* / Q000235:genetics*