LAK cells kill Fas- cancer cells using the Tag7/Hsp70 protein complex secreted from the Golgi apparatus.
Yashin
D V
DV
Institute of Gene Biology, Russian Academy of Sciences, Moscow.
Sashchenko
L P
LP
Dukhanina
E A
EA
Romanova
E A
EA
Luk'yanova
T I
TI
Kabanova
O D
OD
Sorokin
V A
VA
Gnuchev
N V
NV
D000818:Animals; D020126:Brefeldin A / Q000494:pharmacology; D002478:Cells, Cultured; D016207:Cytokines / Q000737:chemistry / Q000276:immunology* / Q000302:isolation & purification / Q000378:metabolism; D003602:Cytotoxicity, Immunologic; D004533:Egtazic Acid / Q000494:pharmacology; D004586:Electrophoresis; D006056:Golgi Apparatus / Q000276:immunology / Q000378:metabolism*; D018840:HSP70 Heat-Shock Proteins / Q000737:chemistry / Q000276:immunology* / Q000302:isolation & purification / Q000378:metabolism; D006801:Humans; D020014:K562 Cells; D015979:Killer Cells, Lymphokine-Activated / Q000166:cytology / Q000276:immunology*; D008565:Membrane Proteins / Q000737:chemistry / Q000276:immunology / Q000302:isolation & purification / Q000378:metabolism; D051379:Mice; D011500:Protein Synthesis Inhibitors / Q000494:pharmacology; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology; D019014:fas Receptor / Q000235:genetics / Q000276:immunology*
D016207:Cytokines; D018840:HSP70 Heat-Shock Proteins; D008565:Membrane Proteins; C491878:PGLYRP1 protein, human; C113582:Pglyrp1 protein, mouse; D011500:Protein Synthesis Inhibitors; D014409:Tumor Necrosis Factor-alpha; D019014:fas Receptor; D020126:Brefeldin A; D004533:Egtazic Acid