title: Abnormal cortical voice processing in autism.
abstract: Impairments in social interaction are a key feature of autism and are associated with atypical social information processing. Here we report functional magnetic resonance imaging (fMRI) results showing that individuals with autism failed to activate superior temporal sulcus (STS) voice-selective regions in response to vocal sounds, whereas they showed a normal activation pattern in response to nonvocal sounds. These findings suggest abnormal cortical processing of socially relevant auditory information in autism.
authors.affiliation: ERM 0205, INSERM-CEA, DRM, DSV, Service Hospitalier Frédéric Joliot, 4, place du General Leclerc, 91406, Orsay, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Gervais
authors.forename: Pascal
authors.initials: P
authors.lastname: Belin
authors.forename: Nathalie
authors.initials: N
authors.lastname: Boddaert
authors.forename: Marion
authors.initials: M
authors.lastname: Leboyer
authors.forename: Arnaud
authors.initials: A
authors.lastname: Coez
authors.forename: Ignacio
authors.initials: I
authors.lastname: Sfaello
authors.forename: Catherine
authors.initials: C
authors.lastname: Barthélémy
authors.forename: Francis
authors.initials: F
authors.lastname: Brunelle
authors.forename: Yves
authors.initials: Y
authors.lastname: Samson
authors.forename: Mônica
authors.initials: M
authors.lastname: Zilbovicius
mesh_terms: D000328:Adult; D001303:Auditory Cortex / Q000000981:diagnostic imaging / Q000503:physiopathology*; D001307:Auditory Perception / Q000502:physiology*; D001321:Autistic Disorder / Q000000981:diagnostic imaging / Q000503:physiopathology*; D001931:Brain Mapping; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011859:Radiography