title: Low CSF hypocretin-1/orexin-A associated with hypersomnia secondary to hypothalamic lesion in a case of multiple sclerosis.
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Oka
authors.forename: Takashi
authors.initials: T
authors.lastname: Kanbayashi
authors.forename: Takahiro
authors.initials: T
authors.lastname: Mezaki
authors.forename: Kazumi
authors.initials: K
authors.lastname: Iseki
authors.forename: Jun
authors.initials: J
authors.lastname: Matsubayashi
authors.forename: Gaku
authors.initials: G
authors.lastname: Murakami
authors.forename: Masaru
authors.initials: M
authors.lastname: Matsui
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Shimizu
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Shibasaki
mesh_terms: D000328:Adult; D002352:Carrier Proteins / Q000134:cerebrospinal fluid*; D006970:Disorders of Excessive Somnolence / Q000134:cerebrospinal fluid* / Q000209:etiology / Q000473:pathology*; D015536:Down-Regulation / Q000502:physiology; D005260:Female; D006801:Humans; D007031:Hypothalamus / Q000473:pathology* / Q000503:physiopathology*; D047908:Intracellular Signaling Peptides and Proteins; D008775:Methylprednisolone / Q000627:therapeutic use; D009103:Multiple Sclerosis / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D009479:Neuropeptides / Q000134:cerebrospinal fluid* / Q000172:deficiency; D000068797:Orexins; D020923:REM Sleep Parasomnias / Q000134:cerebrospinal fluid / Q000209:etiology / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D002352:Carrier Proteins; C000596229:HCRT protein, human; D047908:Intracellular Signaling Peptides and Proteins; D009479:Neuropeptides; D000068797:Orexins; D008775:Methylprednisolone