title: Protein structure-based design, synthesis strategy and in vitro pharmacological characterization of estrogen receptor alpha and beta selective compounds.
authors.affiliation: EnTec Ltd, Jena, Germany. alexander.hillisch@bayerhealthcare.com
authors.forename: A
authors.initials: A
authors.lastname: Hillisch
authors.forename: O
authors.initials: O
authors.lastname: Peters
authors.forename: D
authors.initials: D
authors.lastname: Kosemund
authors.forename: G
authors.initials: G
authors.lastname: Müller
authors.forename: A
authors.initials: A
authors.lastname: Walter
authors.forename: W
authors.initials: W
authors.lastname: Elger
authors.forename: K H
authors.initials: KH
authors.lastname: Fritzemeier
mesh_terms: D000595:Amino Acid Sequence; D015195:Drug Design; D047628:Estrogen Receptor alpha; D047629:Estrogen Receptor beta; D008024:Ligands; D008958:Models, Molecular; D008969:Molecular Sequence Data; D011485:Protein Binding; D011487:Protein Conformation; D011960:Receptors, Estrogen / Q000737:chemistry / Q000187:drug effects* / Q000378:metabolism; D020845:Selective Estrogen Receptor Modulators / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D017386:Sequence Homology, Amino Acid
chemical_list: D047628:Estrogen Receptor alpha; D047629:Estrogen Receptor beta; D008024:Ligands; D011960:Receptors, Estrogen; D020845:Selective Estrogen Receptor Modulators