title: Cryptococcal thyroiditis and hyperthyroidism.
abstract: We report a case of cryptococcal thyroiditis presenting with hyperthyroidism that evolved through a transient euthyroid phase to hypothyroidism and finally recovered to normal function. This four-phase clinical presentation is similar to that of subacute thyroiditis, and it is unusual in the setting of infectious nonviral thyroiditis. Cryptococcal thyroiditis is rare; only three cases have been reported. Our patient is the first who survived the disseminated cryptococcal infection with thyroid involvement, thus enabling longitudinal clinical and endocrinologic follow-up.
authors.affiliation: Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109-0028, USA.
authors.forename: Anca M
authors.initials: AM
authors.lastname: Avram
authors.forename: Christine A
authors.initials: CA
authors.lastname: Sturm
authors.forename: Claire W
authors.initials: CW
authors.lastname: Michael
authors.forename: James C
authors.initials: JC
authors.lastname: Sisson
authors.forename: Craig A
authors.initials: CA
authors.lastname: Jaffe
mesh_terms: D000328:Adult; D003453:Cryptococcosis / Q000382:microbiology / Q000473:pathology; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D005500:Follow-Up Studies; D006801:Humans; D007037:Hypothyroidism / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D011877:Radionuclide Imaging; D013966:Thyroiditis / Q000150:complications* / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000473:pathology