Visual hallucination in Parkinson's disease with FDG PET.
To determine the characteristics of cerebral glucose metabolism in Parkinson's disease patients with visual hallucinations, group comparison studies using [18F]fluorodeoxyglucose positron emission tomography were performed. Nondemented Parkinson's disease patients in advanced stages were classified into two groups: (1) patients without visual hallucinations; (2) patients with visual hallucinations. Compared to patients without hallucinations, the relative regional cerebral glucose metabolic rate was greater in the frontal areas in patients with visual hallucinations, and the increase reached a significant level in the left superior frontal gyrus. Relative frontal hypermetabolism may be a feature of Parkinson's disease patients with visual hallucinations.
Nagano-Saito
Atsuko
A
Department of Brain Science and Molecular Imaging, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Obu, Japan.|Department of Neurology, Chubu National Hospital, Obu, Japan.
Washimi
Yukihiko
Y
Department of Neurology, Chubu National Hospital, Obu, Japan.
Arahata
Yutaka
Y
Department of Brain Science and Molecular Imaging, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Obu, Japan.|Department of Neurology, Chubu National Hospital, Obu, Japan.
Iwai
Katsushige
K
Department of Neurology, Chubu National Hospital, Obu, Japan.
Kawatsu
Shoji
S
Department of Brain Science and Molecular Imaging, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Obu, Japan.
Ito
Kengo
K
Department of Brain Science and Molecular Imaging, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Obu, Japan.
Nakamura
Akinori
A
Department of Brain Science and Molecular Imaging, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Obu, Japan.
Abe
Yuji
Y
Department of Neurology, Chubu National Hospital, Obu, Japan.
Yamada
Takako
T
Department of Neurology, Chubu National Hospital, Obu, Japan.
Kato
Takashi
T
Department of Brain Science and Molecular Imaging, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Obu, Japan.
Kachi
Teruhiko
T
Department of Neurology, Chubu National Hospital, Obu, Japan.
D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging / Q000378:metabolism*; D005260:Female; D019788:Fluorodeoxyglucose F18; D005625:Frontal Lobe / Q000000981:diagnostic imaging / Q000378:metabolism; D007839:Functional Laterality; D005947:Glucose / Q000378:metabolism*; D006212:Hallucinations / Q000000981:diagnostic imaging / Q000209:etiology* / Q000378:metabolism*; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis / Q000209:etiology; D009778:Occipital Lobe / Q000000981:diagnostic imaging / Q000378:metabolism; D010300:Parkinson Disease / Q000150:complications* / Q000000981:diagnostic imaging / Q000378:metabolism*; D017397:Prefrontal Cortex / Q000000981:diagnostic imaging / Q000378:metabolism; D019275:Radiopharmaceuticals; D012720:Severity of Illness Index; D014055:Tomography, Emission-Computed
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D005947:Glucose