title: [Adjustment methods of proportional pressure support on weaning during acute aggravation in chronic respiratory failure patients with chronic obstructive pulmonary disease].
abstract: OBJECTIVE
  To study the effects of two adjustment methods of proportional pressure support (PPS) on patients with acute aggravation in chronic respiratory failure of chronic obstructive pulmonary disease.
  
  
  METHODS
  Seventy-five patients were randomized to two groups, 30 in proportional adjustment group and 45 in target adjustment group, respectively. Suitable flow assist (FA) and volume assist (VA) were adjusted with proportional adjustment and target adjustment methods respectively according to the ventilation parameters until the weaning of ventilation.
  
  
  RESULTS
  There were no significant differences in resistance, elastic, FA as well as VA on weaning point, duration of mechanical ventilation, and successful weaning rate between the two groups (all P>0.05).
  
  
  CONCLUSIONS
  The same aim and successful weaning rate could be gained in the target adjustment group compared with the proportional adjustment group. More clinical experience and more intensive care would be needed in the target adjustment group.
authors.affiliation: Intensive Care Unit, Tianjin Third Center Hospital, Tianjin 300170, China.
authors.forename: Shi-yong
authors.initials: SY
authors.lastname: Wang
authors.forename: Chun
authors.initials: C
authors.lastname: Zhan
authors.forename: Na-xin
authors.initials: NX
authors.lastname: Zhang
authors.forename: Ying-zhi
authors.initials: YZ
authors.lastname: Qin
authors.forename: Lei
authors.initials: L
authors.lastname: Xu
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications*; D012121:Respiration, Artificial / Q000379:methods*; D012131:Respiratory Insufficiency / Q000209:etiology / Q000628:therapy*; D015300:Ventilator Weaning / Q000379:methods*