title: Quantitative phase-contrast imaging of cells with phase-sensitive optical coherence microscopy.
abstract: We describe a method for en face phase-contrast imaging of cells with a fiber-based differential phase-contrast optical coherence microscopy system. Recorded en face images are quantitative phase-contrast maps of cells due to spatial variation of the refractive index and (or) thickness of various cellular components. Quantitative phase-contrast images of human epithelial cheek cells obtained with the fiber-based differential phase-contrast optical coherence microscopy system are presented.
authors.affiliation: Department of Biomedical Engineering, University of Texas at Austin, Austin, Texas 78712, USA.
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Rylander
authors.forename: Digant P
authors.initials: DP
authors.lastname: Davé
authors.forename: Taner
authors.initials: T
authors.lastname: Akkin
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Milner
authors.forename: Kenneth R
authors.initials: KR
authors.lastname: Diller
authors.forename: Ashley J
authors.initials: AJ
authors.lastname: Welch
mesh_terms: D002610:Cheek; D004847:Epithelial Cells / Q000166:cytology*; D006801:Humans; D007368:Interferometry; D008858:Microscopy, Phase-Contrast; D009061:Mouth Mucosa / Q000166:cytology; D041623:Tomography, Optical Coherence