title: [No improvement of lipodystrophy syndrome in an HIV-infected patient].
abstract: Lipodystrophy in patients with HIV-infection has been studied intensively to understand its epidemiology and pathophysiology. Recently its development was attributed to a dysregulation of TNF-alpha synthesis' homeostasis by HAART. A few years ago it was found that pentoxifylline decreases TNF-alpha production. We describe one HIV-infected patient, with lipodystrophy syndrome, treated with pentoxifylline without any improvement of lipodystrophic symptoms.
authors.affiliation: Divisione Clinicizzata di Malattie Infettive, Ospedale Civile Maggiore Borgo Trento, Verona. masino69@hotmail.com
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Lanzafame
authors.forename: Federica
authors.initials: F
authors.lastname: Faggian
authors.forename: Emanuela
authors.initials: E
authors.lastname: Lattuada
authors.forename: Dario
authors.initials: D
authors.lastname: Antolini
authors.forename: Ercole
authors.initials: E
authors.lastname: Concia
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D015658:HIV Infections / Q000188:drug therapy*; D039682:HIV-Associated Lipodystrophy Syndrome / Q000139:chemically induced / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D008297:Male; D010431:Pentoxifylline / Q000627:therapeutic use*; D017211:Treatment Failure; D014409:Tumor Necrosis Factor-alpha / Q000187:drug effects* / Q000378:metabolism
chemical_list: D014409:Tumor Necrosis Factor-alpha; D010431:Pentoxifylline