Myocardial injury during standard treatment of an adult with status asthmaticus.
Asthma affects 5%-10% of adults in the United States. Older adults (> 65 years) with asthma have higher rates of fatal asthma than younger adults. The occurrence of a respiratory emergency, such as status asthmaticus, would seem likely to create a situation of cardiopulmonary dysfunction conducive to myocardial ischemia. However, multiple studies of fatal or near-fatal asthma have failed to incriminate myocardial infarction as a contributing factor. We report a patient without underlying coronary artery disease who sustained myocardial injury consistent with myocardial ischemia and infarction during status asthmaticus while receiving recommended treatment without intravenous sympathomimetics or theophylline.
Iskandar
Said B
SB
The Quillen Veterans Affairs Medical Center, Mountain Home, Tennessee , USA 37684-4000, USA.
Mathai
Mathew G
MG
Byrd
Ryland P
RP
Roy
Thomas M
TM
D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use*; D003402:Creatine Kinase / Q000096:biosynthesis / Q000097:blood; D052279:Creatine Kinase, MB Form; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007527:Isoenzymes / Q000096:biosynthesis / Q000097:blood; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000209:etiology* / Q000378:metabolism; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency / Q000209:etiology / Q000628:therapy; D013224:Status Asthmaticus / Q000150:complications / Q000188:drug therapy* / Q000628:therapy; D016896:Treatment Outcome
D000318:Adrenergic beta-Agonists; D018927:Anti-Asthmatic Agents; D005938:Glucocorticoids; D007527:Isoenzymes; D003402:Creatine Kinase; D052279:Creatine Kinase, MB Form