High temporal and spatial resolution 4D MRA using spiral data sampling and sliding window reconstruction.
Contrast-enhanced magnetic resonance angiography (CE-MRA) requires high spatial resolution to demonstrate detailed vasculature and high temporal resolution to capture the contrast bolus. Sparse bright voxels in MRA permit substantial undersampling in MRI data acquisition, allowing simultaneous high temporal and spatial resolution. We developed a time-resolved 3D MRA technique using the efficient spiral sampling trajectory, and performed off-resonance corrections using inhomogeneity field maps. View sharing and sliding window reconstruction were utilized to generate high temporal resolution. High-resolution 3D angiograms were generated at 1-2 s per frame, with a 5-8 ml gadolinium dose, in patients with vascular disease.
Zhu
He
H
Department of Radiology, University of Pittsburg, Pittsburgh, Pennsylvania 15213, USA.
Buck
David G
DG
Zhang
Zhenghui
Z
Zhang
Honglei
H
Wang
Paul
P
Stenger
V Andrew
VA
Prince
Martin R
MR
Wang
Yi
Y
D001161:Arteriosclerosis / Q000175:diagnosis*; D003287:Contrast Media; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007866:Leg / Q000098:blood supply*; D018810:Magnetic Resonance Angiography / Q000379:methods*
D003287:Contrast Media; D019786:Gadolinium DTPA