A New STLV-1 in a household pet Cercopithecus nictitans from Gabon.
A recent serological survey of wild-born captive monkeys from Gabon, Central Africa, revealed that 1 of 20 Cercopithecus nictitans tested was infected with a new simian T cell lymphotropic virus type 1 (STLV-1). We investigated the molecular relationship between the STLV-1 strain present in this C. nictitans (CN01) and the other available HTLV/STLV strains. Phylogenetic analysis of the env (gp46 and gp21) region showed that the new STLV(nict) clusters with the HTLV-1/STLV-1 group and not with the other nictitans STLVs belonging to the STLV-3 group. Moreover, our new STLV(nict) is closely related to the molecular subtype D, which presently includes five HTLV-1 and three mandrill STLV-1 strains from Gabon and two from Cameroon. These data show that C. nictitans may be the natural carrier of two different molecular types of STLV, one related to STLV-3 and the other possibly one of the simian STLV type 1 counterparts of HTLV-1 subtype D.
Makuwa
Maria
M
Laboratoire de Virologie, UGENET, CDP, Centre International de Recherches Médicales, Franceville, Gabon. mmakuwa@yahoo.com
Souquiere
Sandrine
S
Telfer
Paul
P
Mouinga-Ondeme
Augustin
A
Bourry
Olivier
O
Roques
Pierre
P
D000818:Animals; D002353:Carrier State; D002521:Cercopithecus / Q000821:virology*; D004279:DNA, Viral / Q000737:chemistry / Q000302:isolation & purification; D006800:Deltaretrovirus Infections / Q000662:veterinary* / Q000821:virology; D005681:Gabon; D005814:Genes, Viral; D015752:Genes, env; D005838:Genotype; D015368:Human T-lymphotropic virus 1 / Q000235:genetics; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D008992:Monkey Diseases / Q000821:virology*; D010802:Phylogeny; D011533:Proviruses / Q000235:genetics; D017422:Sequence Analysis, DNA; D015303:Simian T-lymphotropic virus 1 / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification
D004279:DNA, Viral