title: Further evidence for paternal inheritance of mitochondrial DNA in the sheep (Ovis aries).
abstract: The mitochondrial DNA of 172 sheep from 48 families were typed by using PCR-RFLP, direct amplification of the repeated sequence domain and sequencing analysis. The mitochondrial DNA from three lambs in two half-sib families were found to show paternal inheritance. Our findings provide direct evidence of paternal inheritance of mitochondria DNA in sheep. A total of 12 highly polymorphic microsatellite markers, which mapped on different chromosomes, were employed to type the sheep population to confirm family relationships. Possible mechanisms of paternal inheritance are discussed.
authors.affiliation: Department of Animal Science and Technology, China Agricultural University, Beijing 100094, China.
authors.forename: X
authors.initials: X
authors.lastname: Zhao
authors.forename: N
authors.initials: N
authors.lastname: Li
authors.forename: W
authors.initials: W
authors.lastname: Guo
authors.forename: X
authors.initials: X
authors.lastname: Hu
authors.forename: Z
authors.initials: Z
authors.lastname: Liu
authors.forename: G
authors.initials: G
authors.lastname: Gong
authors.forename: A
authors.initials: A
authors.lastname: Wang
authors.forename: J
authors.initials: J
authors.lastname: Feng
authors.forename: C
authors.initials: C
authors.lastname: Wu
mesh_terms: D000818:Animals; D001483:Base Sequence; D017931:DNA Primers / Q000235:genetics; D004272:DNA, Mitochondrial / Q000235:genetics*; D005220:Fathers; D005260:Female; D005838:Genotype; D040941:Heredity / Q000235:genetics*; D007178:Inbreeding; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics; D008969:Molecular Sequence Data; D010375:Pedigree; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D012756:Sheep / Q000235:genetics*
chemical_list: D017931:DNA Primers; D004272:DNA, Mitochondrial