title: Preimplantation diagnosis in Switzerland--birth of a healthy child after polar body biopsy.
abstract: In Switzerland preimplantation genetic diagnosis is limited by law to polar body biopsy (PBB). The indications for PBB include unexplained recurrent miscarriage and improvement of the outcome of in vitro fertilisation (IVF) cycles in women at an advanced reproductive age. In this article we report the first birth of a healthy child after polar body biopsy in Switzerland in a case of unexplained miscarriage after IVF.
authors.affiliation: Clinic of Endocrinology, Department of Obstetrics and Gynaecology, University Hospital Zurich, Switzerland. bruno.imthurn@usz.ch
authors.forename: Bruno
authors.initials: B
authors.lastname: Imthurn
authors.forename: Josef
authors.initials: J
authors.lastname: Achermann
authors.forename: Marianne
authors.initials: M
authors.lastname: Klug Arter
authors.forename: Ervin
authors.initials: E
authors.lastname: Macas
mesh_terms: D000026:Abortion, Habitual / Q000235:genetics*; D000328:Adult; D020732:Cytogenetic Analysis / Q000379:methods*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D011247:Pregnancy; D011256:Pregnancy Outcome; D019836:Preimplantation Diagnosis / Q000379:methods*; D013557:Switzerland