title: Infectious and inflammatory mechanisms in preterm birth and cerebral palsy.
abstract: OBJECTIVE
  In a thesis examine infectious and inflammatory mechanisms involved in preterm birth and cerebral palsy.
  
  
  METHODS
  Four cross-sectional studies and a case control study.
  
  
  RESULTS
  Microbial invasion of the amniotic cavity and inflammation in this population of Swedish women in preterm labor and preterm prelabor rupture of membranes was similar to that reported in data from populations with a higher incidence of preterm birth. Our data support an association between antenatal infection/inflammation and cerebral palsy.
  
  
  CONCLUSIONS
  Infectious and inflammatory mechanisms are involved in preterm birth and cerebral palsy in a population with low incidence of preterm birth.
authors.affiliation: Perinatal Center, Department of Obstetrics and Gynecology, Institute for the Health of Women and Children, The Sahlgrenska Academy at Göteborg University, SE-41685, Sweden. bo.jacobsson@obgyn.gu.se
authors.forename: Bo
authors.initials: B
authors.lastname: Jacobsson
mesh_terms: D000649:Amniocentesis; D000653:Amniotic Fluid / Q000276:immunology; D016022:Case-Control Studies; D002547:Cerebral Palsy / Q000276:immunology*; D002821:Chorioamnionitis / Q000276:immunology / Q000382:microbiology; D003430:Cross-Sectional Studies; D016207:Cytokines / Q000032:analysis; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000276:immunology* / Q000382:microbiology; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000276:immunology*; D007752:Obstetric Labor, Premature / Q000276:immunology / Q000382:microbiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology* / Q000382:microbiology; D013548:Sweden
chemical_list: D016207:Cytokines