title: Links between apoptosis, proliferation and the cell cycle.
abstract: Many physiological processes, including proper tissue development and homeostasis, require a balance between apoptosis and cell proliferation. All somatic cells proliferate via a mitotic process determined by progression through the cell cycle. Apoptosis (programmed cell death) occurs in a wide variety of physiological settings, where its role is to remove harmful, damaged or unwanted cells. Apoptosis and cell proliferation are linked by cell-cycle regulators and apoptotic stimuli that affect both processes. This review covers recent developments in the field and examines new evidence of the interconnection between apoptosis and cell proliferation.
authors.affiliation: Department of Medical Laboratory Sciences, College of Applied Medical Sciences, King Faisal University, P.O. Box 2114, Dammam 31451, Saudi Arabia. faris_alenzi@hotmail.com
authors.forename: F Q B
authors.initials: FQ
authors.lastname: Alenzi
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D002453:Cell Cycle / Q000502:physiology*; D018797:Cell Cycle Proteins / Q000502:physiology; D002455:Cell Division / Q000502:physiology; D006801:Humans; D051379:Mice
chemical_list: D018797:Cell Cycle Proteins