Lignoren, a new sesquiterpenoid metabolite from Trichoderma lignorum HKI 0257.
The new compound lignoren (1) was isolated from Trichoderma lignorum HKI 0257 by chromatographic methods. This metabolite has a santalane-like structure, which was elucidated by mass spectrometric and NMR spectroscopic investigations. Lignoren (1) shows a moderate narrow-spectrum of antibacterial and antifungal activity.
Berg
Albrecht
A
Hans-Knöll-Institute for Natural Products Research, Beutenbergstr. 11a, D-07745 Jena, Germany. Albrecht.Berg@hki-jena.de
Wangun
Hilaire V Kemami
HV
Nkengfack
Augusin E
AE
Schlegel
Brigitte
B
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology*; D014242:Trichoderma / Q000254:growth & development / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D012717:Sesquiterpenes; C493325:lignoren