title: Effects of atorvastatin (10 mg) on hemostatic and inflammatory parameters in hyperlipidemic patients with angiographically proven coronary artery disease.
abstract: Hyperlipidemic patients with coronary heart disease were treated with atorvastatin, and its effects on hemostatic and inflammatory parameters were assessed. After 3 months of therapy, the plasma levels of plasminogen activator inhibitor, prothrombin fragment 1+2, highly sensitive C-reactive protein, von Willebrand factor, and fibrinogen were significantly reduced; no significant reductions were observed in lipoprotein(a) and tissue plasminogen activator antigen levels.
authors.affiliation: Department of Cardiology, Faculty of Medicine, Başkent University, Adana, Turkey.
authors.forename: Abdullah
authors.initials: A
authors.lastname: Tekin
authors.forename: Göknur
authors.initials: G
authors.lastname: Tekin
authors.forename: Deniz
authors.initials: D
authors.lastname: Güzelsoy
authors.forename: Ayşem
authors.initials: A
authors.lastname: Kaya
authors.forename: Ciğdem Vural
authors.initials: CV
authors.lastname: Gürel
authors.forename: Zerrin
authors.initials: Z
authors.lastname: Yiğit
authors.forename: Turgut
authors.initials: T
authors.lastname: Ulutin
mesh_terms: D000368:Aged; D000924:Anticholesteremic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D000069059:Atorvastatin; D002097:C-Reactive Protein / Q000032:analysis; D015897:Comorbidity; D017023:Coronary Angiography; D003327:Coronary Disease / Q000453:epidemiology; D004730:Endothelium, Vascular / Q000187:drug effects / Q000503:physiopathology; D005260:Female; D006487:Hemostasis / Q000187:drug effects*; D006538:Heptanoic Acids / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000188:drug therapy* / Q000453:epidemiology / Q000503:physiopathology*; D017270:Lipoprotein(a) / Q000097:blood; D008297:Male; D008875:Middle Aged; D010446:Peptide Fragments / Q000097:blood; D011446:Prospective Studies; D011516:Prothrombin; D011758:Pyrroles / Q000494:pharmacology* / Q000627:therapeutic use; D010959:Tissue Plasminogen Activator / Q000097:blood
chemical_list: D000924:Anticholesteremic Agents; D006538:Heptanoic Acids; D017270:Lipoprotein(a); D010446:Peptide Fragments; D011758:Pyrroles; C045879:prothrombin fragment 1.2; D011516:Prothrombin; D002097:C-Reactive Protein; D000069059:Atorvastatin; D010959:Tissue Plasminogen Activator