title: [Surgical treatment for temporal lobe epilepsy in patients over age 50 years].
abstract: We retrospectively analyzed 4 patients over age 50 (52 - 57) years with intractable medial temporal lobe epilepsy(MTLE) who underwent the anterior temporal lobectomy with hippocampectomy. Case 1 had MTLE with old brain abscess in the left lateral temporal lobe and Cases 2 - 4 had MTLE with histologically verified hippocampal sclerosis. In Cases 2 - 4, although the onset of seizures occurred 26 to 37 years prior to the time of surgery, there was no mental problem (IQ = 87 - 100). In Cases 1, chronic invasive electrocorticography recording using subdural electrodes was obtained, while in Case 2 - 4, the epileptogenic region was defined by noninvasive preoperative evaluation. Postoperatively, all patients obtained a meaningful improvement, becoming either free from seizures or only experiencing a rare seizure, and returned to work or usual activities without surgical complications. Surgery for MTLE appears to be effective for older individuals and carries a small risk of postoperative complications.
authors.affiliation: Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
authors.forename: Takato
authors.initials: T
authors.lastname: Morioka
authors.forename: Kimiaki
authors.initials: K
authors.lastname: Hashiguchi
authors.forename: Kimiko
authors.initials: K
authors.lastname: Fukui
authors.forename: Tadao
authors.initials: T
authors.lastname: Kawamura
authors.forename: Masayuki
authors.initials: M
authors.lastname: Sasaki
authors.forename: Futoshi
authors.initials: F
authors.lastname: Mihara
authors.forename: Tomio
authors.initials: T
authors.lastname: Sasaki
mesh_terms: D038481:Anterior Temporal Lobectomy; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006624:Hippocampus / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods*; D012189:Retrospective Studies; D012598:Sclerosis / Q000150:complications