title: Treatment of microfilaraemics with DEC and its effect on vector infection and infectivity in tribal and non-tribal areas of Bankura district, West Bengal, India.
abstract: Single course DEC treatment (6 mg/kg body weight/day for 12 days) was administered to 66 tribal and 442 non-tribal microfilaria (mf) carriers detected through a Filariasis survey in Bankura district, West Bengal, India. All the mf carriers remained amicrofilaraemic on 22nd, 180th and 365th post-treatment day. As a result of DEC treatment to the mf carriers, vector (Culex quinquefasciatus) infection rate in tribal study areas reduced from 2.06% to 1.07%. Infectivity rate was "nil" both before and after treatment. In non-tribal study areas, vector infection rate reduced from 4.33% to 2.22% and infectivity rate from 0.51% to 0.29%.
authors.affiliation: Mosquito Research Unit, Department of Zoology, Burdwan University, Burdwan-713 104 West Bengal, India.
authors.forename: G
authors.initials: G
authors.lastname: Chandra
authors.forename: S K
authors.initials: SK
authors.lastname: Rudra
authors.forename: S N
authors.initials: SN
authors.lastname: Chatterjee
mesh_terms: D000818:Animals; D002353:Carrier State / Q000188:drug therapy* / Q000469:parasitology; D009033:Culicidae / Q000469:parasitology; D004049:Diethylcarbamazine / Q000008:administration & dosage*; D005368:Filariasis / Q000188:drug therapy; D005369:Filaricides / Q000008:administration & dosage*; D006801:Humans; D007194:India; D007303:Insect Vectors / Q000469:parasitology*; D008842:Microfilariae / Q000187:drug effects*; D014958:Wuchereria bancrofti / Q000187:drug effects / Q000302:isolation & purification
chemical_list: D005369:Filaricides; D004049:Diethylcarbamazine