title: Massive hepatic artery atherosclerosis of an otherwise suitable donor liver: a case report.
abstract: Most of the few reports about hepatic artery disease found in the literature describe hepatic artery aneurysms or hepatic artery calcifications. Atherosclerosis of the hepatic artery is not commonly evaluated during deceased donor liver procurement. Herein we present a case of a stable 47-year-old Caucasian female donor whose liver function tests were within normal limits and a liver biopsy showed less than 5% steatosis. The liver when received at our center appeared grossly unremarkable. Back-table evaluation showed a complete occlusion of the trunk of the proper hepatic artery. The pathology report revealed hepatic occlusion due to arterial atherosclerosis. Transplantation was canceled, and the liver was used for isolated hepatocyte perfusion, revealing < 25% hepatocyte viability. Hepatic artery atherosclerosis and patency need to be evaluated at the time of procurement to prevent recipient morbidity due to anesthetic induction, or initiation of a recipient abdominal incision prior to declining the liver graft for this rare finding.
authors.affiliation: Division of Transplantation, Department of Surgery, Virgia Commonwealth University, Richmond, Virginia 23298-0248, USA.
authors.forename: D
authors.initials: D
authors.lastname: Maluf
authors.forename: B D
authors.initials: BD
authors.lastname: Clark
authors.forename: A H
authors.initials: AH
authors.lastname: Cotterell
authors.forename: M P
authors.initials: MP
authors.lastname: Posner
authors.forename: R A
authors.initials: RA
authors.lastname: Fisher
mesh_terms: D001012:Aorta, Abdominal / Q000473:pathology; D001161:Arteriosclerosis / Q000473:pathology* / Q000601:surgery*; D001926:Brain Death; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006499:Hepatic Artery / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D016031:Liver Transplantation / Q000379:methods*; D008875:Middle Aged; D020858:Tissue and Organ Harvesting / Q000379:methods