title: Teaching resource. Beta-catenin signaling and axis specification.
abstract: This animation provides a representation of the beta-catenin signaling pathway in response to fertilization and the process of axis specification that occurs early in development. The process shown is based on analysis of embryos of the amphibian Xenopus. This animation would be useful in illustrating events that occur early in embryogenesis and how embryos become polarized as a consequence of localized signaling processes.
authors.affiliation: Howard Hughes Medical Institute and Department of Pharmacology, University of Washington School of Medicine, Seattle, WA 98195, USA. rtmoon@u.washington.edu
authors.forename: Randall T
authors.initials: RT
authors.lastname: Moon
mesh_terms: D000818:Animals; D003598:Cytoskeletal Proteins / Q000502:physiology*; D004625:Embryo, Nonmammalian / Q000502:physiology; D004627:Embryonic Induction / Q000502:physiology; D005306:Fertilization / Q000502:physiology; D009040:Motion Pictures; D020897:Organizers, Embryonic / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D015534:Trans-Activators / Q000502:physiology*; D014981:Xenopus / Q000235:genetics*; D029867:Xenopus Proteins / Q000502:physiology; D051176:beta Catenin
chemical_list: C495266:CTNNB1 protein, Xenopus; D003598:Cytoskeletal Proteins; D015534:Trans-Activators; D029867:Xenopus Proteins; D051176:beta Catenin