title: Randomised controlled trial assessing the impact of a nurse delivered, flow monitored protocol for optimisation of circulatory status after cardiac surgery.
abstract: OBJECTIVE
  To assess whether a nurse led, flow monitored protocol for optimising circulatory status in patients after cardiac surgery reduces complications and shortens stay in intensive care and hospital.
  
  
  METHODS
  Randomised controlled trial.
  
  
  METHODS
  Intensive care unit and cardiothoracic unit of a university teaching hospital.
  
  
  METHODS
  174 patients who underwent cardiac surgery between April 2000 and January 2003.
  
  
  METHODS
  Patients were allocated to conventional haemodynamic management or to an algorithm guided by oesophageal Doppler flowmetry to maintain a stroke index above 35 ml/m2.
  
  
  RESULTS
  26 control patients had postoperative complications (two deaths) compared with 17 (four deaths) protocol patients (P = 0.08). Duration of hospital stay in the protocol group was significantly reduced from a median of nine (interquartile range 7-12) days to seven (7-10) days (P = 0.02). The mean duration of hospital stay was reduced from 13.9 to 11.4 days, a saving in hospital bed days of 18% (95% confidence interval -12% to 47%). Usage of intensive care beds was reduced by 23% (-8% to 59%).
  
  
  CONCLUSIONS
  A nurse delivered protocol for optimising circulatory status in the early postoperative period after cardiac surgery may significantly shorten hospital stay.
authors.affiliation: Bloomsbury Institute of Intensive Care Medicine, Department of Medicine and Wolfson Institute of Biomedical Research, University College London, Middlesex Hospital, London W1T 3AA.
authors.forename: Moira
authors.initials: M
authors.lastname: McKendry
authors.forename: Helen
authors.initials: H
authors.lastname: McGloin
authors.forename: Debbie
authors.initials: D
authors.lastname: Saberi
authors.forename: Libby
authors.initials: L
authors.lastname: Caudwell
authors.forename: Anthony R
authors.initials: AR
authors.lastname: Brady
authors.forename: Mervyn
authors.initials: M
authors.lastname: Singer
mesh_terms: D000368:Aged; D002315:Cardiopulmonary Bypass / Q000451:nursing*; D002985:Clinical Protocols; D003326:Coronary Circulation / Q000502:physiology*; D003422:Critical Care; D005260:Female; D006331:Heart Diseases / Q000451:nursing / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D017078:Laser-Doppler Flowmetry; D008297:Male; D016896:Treatment Outcome