Hypercalcemic hypocalciuria: a critical differential diagnosis for hyperparathyroidism.
A differential diagnosis for hyperparathyroidism includes all causes of hypercalcemia; the primary causes of which are primary hyperparathyroidism and humoral hypercalcemia of malignancy. Benign familial hypocalciuric hypercalcemia is a rare condition of primary importance because failure to recognize this entity leads to unnecessary surgery. There are a plethora of other rare causes of hypercalcemia that can be distinguished from primary hyperparathyroidism by history and laboratory profiles. This article discusses the main and less common causes of hypercalcemia and provides guidance for distinguishing among them.
Schwartz
Seth R
SR
Department of Otolaryngology Head and Neck Surgery, University of Washington Medical Center, 1959 Northeast Pacific Avenue, Seattle, WA 98195, USA.
Futran
Neal D
ND
D002118:Calcium / Q000652:urine*; D003937:Diagnosis, Differential; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D006961:Hyperparathyroidism / Q000175:diagnosis* / Q000378:metabolism; D010257:Paraneoplastic Syndromes / Q000175:diagnosis
D002118:Calcium