[Bilateral pulmonary nodules in an HIV-infected patient].
BACKGROUND
Although infectious causes are the most common source of pulmonary nodules in HIV-infected patients, malignant diseases such as Kaposi sarcoma and lymphoma must also be considered.


METHODS
A 40 year-old man, diagnosed with HIV infection 16 years earlier and with a satisfactory viro-immunological control, was hospitalized for bilateral pulmonary nodules and a dorsal lytic mass. Bone and pleural biopsies showed a malignant epithelioid hemangioendothelioma.


CONCLUSIONS
Epithelioid hemangioendothelioma is an uncommon low grade vascular tumor. We report the first case in an HIV-infected patient. Bilateral pulmonary nodules are common in this malignant disease but are not specific. In a HIV-infected patient, such clinical presentation is associated with numerous differential diagnoses and must be interpreted in relation to the immune status.


CONCLUSIONS
In HIV-patients without immunosuppression, pulmonary nodules are often malignant. With the increased survival of these patients, these etiologies closer to those of non-infected patients.
Burel-Vandenbos
F
F
Service d'anatomie pathologique, Hôpital Pasteur, Nice.
Saint-Paul
M-C
MC
Vandenbos
F
F
De Biasi
C
C
Thyss
A
A
Michiels
J-F
JF
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001706:Biopsy; D018791:CD4 Lymphocyte Count; D003937:Diagnosis, Differential; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology / Q000276:immunology; D018323:Hemangioendothelioma, Epithelioid / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy / Q000821:virology*; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy / Q000821:virology*; D008297:Male; D008940:Mitotic Index; D018714:Radiotherapy, Adjuvant; D003074:Solitary Pulmonary Nodule / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy / Q000821:virology*; D015996:Survival Rate; D014057:Tomography, X-Ray Computed
D000900:Anti-Bacterial Agents