title: Voice quality after treatment for T1a glottic carcinoma--radiotherapy versus laser cordectomy.
abstract: The purpose of this study was to assess the anatomic and functional outcomes and compare the voice quality in patients affected by T1a glottic carcinoma treated with curative intent with radiotherapy or laser cordectomy. Fifty-seven cases were analysed: 27 after curative radiotherapy and 30 after laser cordectomy. All patients were studied with videolaryngostroboscopy, voice analysis by narrow spectrogram, and vocal parameters (Jitter, Shimmer, noise/harmonic ratio, and diplophonia). Videolaryngostroboscopy showed severe glottic inadequacy in 25% of cases treated with radiation and insufficient compensation 'ventricular band' or 'with arytenoid hyperadduction' in 65% of cases after surgery. Severe dysphonia on the electro-acoustic analysis of voice was observed in 25% of cases after radiation and 70% after laser (p < 0.001). Fundamental frequency and vocal parameters showed more favourable results in the radiation group (p < 0.001). Voice assessment showed better results after radiotherapy compared with laser cordectomy. Voice outcome should be carefully considered in the treatment decision for T1 glottic carcinoma.
authors.affiliation: Division of Radiotherapy, University of Piemonte Orientale 'Amedeo Avogadro' and Azienda Ospedaliera 'Maggiore della Carità', Novara, Italy. krengli@tera.it
authors.forename: Marco
authors.initials: M
authors.lastname: Krengli
authors.forename: Mario
authors.initials: M
authors.lastname: Policarpo
authors.forename: Irene
authors.initials: I
authors.lastname: Manfredda
authors.forename: Paolo
authors.initials: P
authors.lastname: Aluffi
authors.forename: Giuseppina
authors.initials: G
authors.lastname: Gambaro
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Panella
authors.forename: Francesco
authors.initials: F
authors.lastname: Pia
mesh_terms: D002277:Carcinoma / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D005931:Glottis / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D014827:Vocal Cords / Q000601:surgery*; D014833:Voice Quality / Q000528:radiation effects