Interaction-controlled HPLC for block copolymer analysis and separation.
An interaction-controlled HPLC technique has been developed to analyze homopolymer precursors in block copolymer systems that are not easily identified by size exclusion chromatography (SEC) and to obtain block copolymers that are homopolymer-free and compositionally narrower than the as-synthesized ones. We demonstrate that a "single peak" in SEC does not necessarily mean that the block copolymers are free of homopolymers (due to limitations in the SEC analysis of block copolymers) and propose to employ the interaction-controlled HPLC strategy for rigorous analysis and purification of block copolymers in terms of their chemical heterogeneity.
Park
Soojin
S
Department of Chemistry and Center for Integrated Molecular Systems, POSTECH, Pohang, 790-784, Korea.
Park
Insun
I
Chang
Taihyun
T
Ryu
Chang Y
CY