Safety-catch approach to orthogonal synthesis of a triazine library.
A novel safety-catch method for orthogonal synthesis of highly pure trisubstituted triazines was developed. Since the polymer-support used in this method is not acid-labile, this strategy can be uniquely applied to the synthesis of acid-sensitive triazine library compounds. This method will dramatically increase the diversity of triazine and other related heterocyclic library compounds.
Khersonsky
Sonya M
SM
Department of Chemistry, New York University, New York, New York 10003, USA.
Chang
Young-Tae
YT
D000215:Acylation; D015394:Molecular Structure; D014227:Triazines / Q000138:chemical synthesis* / Q000737:chemistry
D014227:Triazines