title: Amino porphyrins as photoinhibitors of Gram-positive and -negative bacteria.
abstract: Twenty four aminoporphyrin derivatives have been tested in vitro for their antibacterial photoactivity against Escherichia coli and Staphylococcus aureus. Two of these compounds, bearing polyamine units, exhibited a significant activity especially against Gram-negative bacteria (E. coli).
authors.affiliation: Université de Limoges, Laboratoire de Chimie des Substances Naturelles, 123, Avenue Albert Thomas, 87060 Limoges, France. vincent.sol@unilim.fr
authors.forename: V
authors.initials: V
authors.lastname: Sol
authors.forename: P
authors.initials: P
authors.lastname: Branland
authors.forename: V
authors.initials: V
authors.lastname: Chaleix
authors.forename: R
authors.initials: R
authors.lastname: Granet
authors.forename: M
authors.initials: M
authors.lastname: Guilloton
authors.forename: F
authors.initials: F
authors.lastname: Lamarche
authors.forename: B
authors.initials: B
authors.lastname: Verneuil
authors.forename: P
authors.initials: P
authors.lastname: Krausz
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects* / Q000528:radiation effects*; D008027:Light; D008826:Microbial Sensitivity Tests; D011166:Porphyrins / Q000737:chemistry / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000528:radiation effects*
chemical_list: D000900:Anti-Bacterial Agents; D011166:Porphyrins