Solid-phase synthesis of alpha-(2-(benzylthio)-1,4-dihydro-6-methyl-4-p-tolylpyrimidine-5-carboxamido) acids: a new strategy to create diversity in heterocyclic scaffolds.
Zhang
Lei
L
Program in Chemical Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, Massachusetts 01605, USA.
Rana
Tariq M
TM
D000143:Acids / Q000138:chemical synthesis / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D001554:Benzene / Q000737:chemistry*; D003500:Cyclization; D015195:Drug Design; D006900:Hydroxylation; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D015394:Molecular Structure; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000737:chemistry*
D000143:Acids; D000577:Amides; D011743:Pyrimidines; D013438:Sulfhydryl Compounds; D001554:Benzene; C030986:pyrimidine