h-ERES-y in ER-Golgi transport.
A debate continues over whether the Golgi is a stable organelle or a transient manifestation of continuous membrane flow from specialized ER exit domains (ERES). A new study from daSilva and colleagues shows that in plant cells, individual Golgi always form adjacent to an existing ERES, and that an ERES and its associated Golgi stack move as a single secretory unit. Their results support a model in which Golgi biogenesis correlates with ERES function.
Brandon
Elizabeth
E
Department of Cell Biology, University of Alabama at Birmingham, 1530 3rd Avenue South, Birmingham, AL 35294, USA.
Sztul
Elizabeth
E
D000818:Animals; D022181:COP-Coated Vesicles / Q000378:metabolism / Q000648:ultrastructure; D004721:Endoplasmic Reticulum / Q000378:metabolism* / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000378:metabolism* / Q000648:ultrastructure; D006801:Humans; D007425:Intracellular Membranes / Q000378:metabolism* / Q000648:ultrastructure; D010944:Plants / Q000378:metabolism* / Q000648:ultrastructure; D011485:Protein Binding / Q000502:physiology; D021381:Protein Transport / Q000502:physiology