title: Using daily interactive voice response technology to measure drinking and related behaviors in a pharmacotherapy study.
abstract: BACKGROUND
  Interactive voice response technology (IVR) allows investigators to collect daily measures of drinking, medication adherence, mood, and other treatment-relevant variables that may change day to day during a clinical trial. Despite these advantages, no published studies have used IVR in alcohol pharmacotherapy trials.
  
  
  METHODS
  Subjects provided daily data via IVR during the 12-week treatment period. Seven subjects completed the trial.
  
  
  RESULTS
  We found a high level of participant adherence to the IVR protocol, higher levels of drinking reported by IVR than by a commonly used recall method, and distinct within-day associations between daily mood and alcohol consumption: these could not be obtained through traditional assessment methods.
  
  
  CONCLUSIONS
  IVR seems to be feasible for the collection of daily indicators of treatment outcomes and processes in pharmacotherapy studies among problem drinkers.
authors.affiliation: Lowell P. Weicker, Jr. General Clinical Research Center, Department of Psychiatry, University of Connecticut Health Center, Farmington, Connecticut 06030-2103, USA. kranzler@psychiatry.uchc.edu
authors.forename: Henry R
authors.initials: HR
authors.lastname: Kranzler
authors.forename: Khamis
authors.initials: K
authors.lastname: Abu-Hasaballah
authors.forename: Howard
authors.initials: H
authors.lastname: Tennen
authors.forename: Richard
authors.initials: R
authors.lastname: Feinn
authors.forename: Kevin
authors.initials: K
authors.lastname: Young
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000188:drug therapy* / Q000453:epidemiology / Q000523:psychology; D005260:Female; D006801:Humans; D007407:Interviews as Topic / Q000379:methods*; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009271:Naltrexone / Q000627:therapeutic use*; D010349:Patient Compliance / Q000523:psychology / Q000706:statistics & numerical data*; D010865:Pilot Projects; D018709:Statistics, Nonparametric; D014831:Voice
chemical_list: D009271:Naltrexone