[Incidence of gallbladder stones in renal transplant recipients].
OBJECTIVE
Gallbladder stone is one of the major cause of morbidity in adults. Renal transplantation has been found to increase the risk of gallbladder stone formation. The real incidence of gallbladder stones in renal transplant recipients is not exactly known. We performed this study to identify the risk factors for cholecystolithiasis.


METHODS
We compared the prevalence of gallbladder stone in 222 renal transplantation patients with that in 222 age and sex matched controls. Patients who had chronic liver disease, renal disease, and diabetes were excluded from the control group.


RESULTS
In our study, the incidence of gallbladder stones is 8.6% (19/222 patients) in renal transplantation patients, which was significantly higher than 3.60% (8/222 control) in the control group (p=0.029). In the most of our renal transplantation patients, cholecystolithiasis was asymptomatic. We did not find a difference in age, sex, duration after transplantation, causes of renal failure, resistance index between patients with and without gallbladder stones in renal transplantation patients.


CONCLUSIONS
Our results suggest that the incidence of gallbladder stones is higher in renal transplant recipients than non-transplant population in Korea. Further studies will be needed to focus the factors contributing to the gallbladder stone formation after renal transplantation, especially in regard to immunosuppressive drugs.
Park
Sung Hyun
SH
Department of Internal Medicine, Hanyang University College of Medicine, Gyeonggi, Korea.
Hahm
Joon Soo
JS
Seong
Sang Seokg
SS
Park
Ui Soon
US
Lee
Kyung Hae
KH
Park
Yoon Kyung
YK
Hyun
Yil Sik
YS
Lee
Hang Lak
HL
Han
Dong Soo
DS
Choi
Ho Soon
HS
D000328:Adult; D000368:Aged; D005260:Female; D042882:Gallstones / Q000209:etiology*; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged