Cortical auditory evoked potentials in autism: a review.
The question of etiology in autism remains elusive primarily due to the fact that autism does not result from a single dysfunction but is multi-faceted in nature. Investigations into etiology have ranged from identifying abnormalities in the genome to describing structural/functional brain abnormalities. Bearing in mind the risk of over-simplification, there is still utility in isolating a specific deficit to examine its etiologic contribution. It is known that individuals with autism have difficulty processing auditory information at the cortical level but this is not consistently seen subcortically. In recent years, cortical auditory processing has been extensively researched using event-related potentials (ERPs); however, these results in relation to autism have not been reviewed. This paper will examine this literature and discuss implications for future research.
Bomba
Marie D
MD
Division of Neurology, Hospital for Sick Children, Toronto, Ontario, Canada.
Pang
Elizabeth W
EW
D001321:Autistic Disorder / Q000503:physiopathology*; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D006801:Humans