Novel aspects of skeletal muscle glycogen and its regulation during rest and exercise.
Although it is often viewed as a homogenous substrate, glycogen is comprised of individual granules or 'glycosomes' that vary in their composition, subcellular localization, and metabolism. These differences result in additional levels of regulation allowing granules to be regulated individually or regionally within the cell during both rest and exercise.
Shearer
Jane
J
Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
Graham
Terry E
TE
D003594:Cytoplasmic Granules / Q000378:metabolism; D015444:Exercise / Q000502:physiology*; D006003:Glycogen / Q000378:metabolism*; D006801:Humans; D008830:Microbodies / Q000378:metabolism; D008854:Microscopy, Electron; D008954:Models, Biological; D018482:Muscle, Skeletal / Q000378:metabolism* / Q000648:ultrastructure
D006003:Glycogen