title: [Effects of experimental varicocele on mitochondria calcium and cytochrome C of the epididymis in adolescent rats].
abstract: OBJECTIVE
  To investigate the effects of experimental varicocele on mitochondria calcium and cytochrome C of the epididymal cells in adolescent rats.
  
  
  METHODS
  Forty male adult Wistar rats were divided into two groups randomly: varicocele group (VG) and sham operation group (SOG) by partial ligation or exposure of the left renal vein. Bilateral epididymides were removed after ten
  
  
  RESULTS
  The content of mitochondria weeks. Mitochondria calcium and cytochrome C levels of the epididymal cells were detected. calcium decreased (P < 0.001 ) while that of cytochrome C increased (P < 0.05) markedly in the experimental group compared with SOG.
  
  
  CONCLUSIONS
  Calcium dyshomeostasis and mitochondrial damage of the epididymal cells caused by varicocele may play an important role in leading to subfertility.
authors.affiliation: Department of Pathophysiology, Basic Medical Science College, Jiamusi University, Jiamusi, Heilongjiang 154007, China. MaXiaoRu6433@tom.com
authors.forename: Xiaoru
authors.initials: X
authors.lastname: Ma
authors.forename: Shuqiu
authors.initials: S
authors.lastname: Wang
authors.forename: Yuexin
authors.initials: Y
authors.lastname: Wang
authors.forename: Shuxiang
authors.initials: S
authors.lastname: Wang
authors.forename: Weiqun
authors.initials: W
authors.lastname: Wang
authors.forename: Jianhua
authors.initials: J
authors.lastname: Zhang
authors.forename: Yongyi
authors.initials: Y
authors.lastname: Li
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism*; D045304:Cytochromes c / Q000032:analysis*; D004822:Epididymis / Q000378:metabolism*; D007248:Infertility, Male / Q000209:etiology; D008297:Male; D008928:Mitochondria / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D014646:Varicocele / Q000378:metabolism*
chemical_list: D045304:Cytochromes c; D002118:Calcium