[Sildenafil citrate for erectile dysfunction in male kidney transplant recipients].
OBJECTIVE
To evaluate the efficacy and safety of sildenafil citrate in man kidney transplant recipients with erectile dysfunction.


METHODS
One hundred and seventy married males, aged 26 approximately 50 years, who had received kidney transplantations at least half a year before and whose serum creatinine was under 133 umol/l, were selected randomly in the study. Their sexual function was investigated according to the International Index of Erectile Function-5 (IIEF-5), and those with erectile dysfunction (ED) were treated with oral sildenafil citrate for 6 months. The efficacy was assessed by IIEF-5.


RESULTS
Fifty-three men with ED received oral sildenafil citrate for 6 months. At the end of the treatment, each index in IIEF-5 increased significantly. There were no interactions between sildenafil and cyclosporine and there was no significant adverse effect of sildenafil on the graft function.


CONCLUSIONS
Sildenafil is an effective and safe agent for the treatment of ED in kidney transplant recipients.
Liu
Feng
F
Renal Disease Research Center, Department of Urinary Surgery, XinQiao Hospital, Third Military Medical University, Chongqing 400037, China. liufwh@hotmail.com
Zhang
Genfu
G
Ji
Xining
X
Huang
Chibing
C
Wang
Pingxian
P
Fan
Mingqi
M
D000328:Adult; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000009:adverse effects / Q000627:therapeutic use*; D011687:Purines; D000068677:Sildenafil Citrate; D013450:Sulfones
D010879:Piperazines; D011687:Purines; D013450:Sulfones; D000068677:Sildenafil Citrate