title: Minimized mortality and neurological complications in surgery for chronic arch aneurysm: axillary artery cannulation, selective cerebral perfusion, and replacement of the ascending and total arch aorta.
abstract: OBJECTIVE
  Cerebral complication is still a major concern in surgery for arteriosclerotic aortic arch disease. For preventing this complication, axillary artery cannulation, selective cerebral perfusion, and replacement of the ascending and arch aorta were applied to thoracic aortic aneurysm involving aortic arch.
  
  
  METHODS
  From May 1999 to July 2002, consecutive 39 patients with true aneurysm (29 patients) or chronic aortic dissection (10 patients) involving aortic arch underwent replacement of the ascending and arch aorta with an elephant trunk under hypothermic cardiopulmonary bypass through the axillary artery cannulation and selective cerebral perfusion. The brain was continuously perfused without any intermission through the axillary artery. Concomitant operation included coronary artery bypass grafting (CABG) in two patients, aortic valve replacement (AVR) in one, Bentall operation in two, mitral valve replacement (MVR) in one, and aortic valve sparing operation in one. Patient age at operation was 40-84 (72 + 9) years and 24 of them were older than 70 years of age.
  
  
  RESULTS
  There was one operative death (2.5%) due to bleeding from the left lung, and one hospital death due to respiratory failure. Postoperative permanent neurological dysfunction was found in one patient (2.5%). Two patients presented temporary neurological dysfunction (5%). Thirty-six of the 39 patients were discharged from hospital on foot.
  
  
  CONCLUSIONS
  Continuous perfusion through the axillary artery with selective cerebral perfusion and replacement of the ascending and arch aorta may minimize cerebral complication leading to satisfactory results in patients with chronic aortic aneurysm involving aortic arch.
authors.affiliation: Second Department of Surgery, Yamagata University School of Medicine, Yamagata, Japan.
authors.forename: Yasuhisa
authors.initials: Y
authors.lastname: Shimazaki
authors.forename: Takao
authors.initials: T
authors.lastname: Watanabe
authors.forename: Toshiki
authors.initials: T
authors.lastname: Takahashi
authors.forename: Takashi
authors.initials: T
authors.lastname: Minowa
authors.forename: Kiyoshige
authors.initials: K
authors.lastname: Inui
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Uchida
authors.forename: Masataka
authors.initials: M
authors.lastname: Koshika
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Takeda
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000784:Aortic Dissection / Q000401:mortality / Q000601:surgery*; D001013:Aorta, Thoracic / Q000601:surgery*; D001366:Axillary Artery; D019917:Blood Vessel Prosthesis Implantation / Q000401:mortality; D002315:Cardiopulmonary Bypass; D002544:Cerebral Infarction / Q000209:etiology* / Q000517:prevention & control; D002560:Cerebrovascular Circulation; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010477:Perfusion; D011183:Postoperative Complications / Q000517:prevention & control*; D016896:Treatment Outcome