title: The prostate as a reservoir for HIV-1.
abstract: As the prostate can harbor bacterial and fungal pathogens, it was investigated as a reservoir for HIV. Nine men chronically infected with HIV participated in a crossover trial in which weekly semen samples were collected with and without previous prostate massage (PM). Six of the nine participants had undetectable seminal plasma(SP) HIV RNA in all samples without previous PM, but had detectable SP HIV RNA (> 25 copies/ml) in one to three samples collected after PM.
authors.affiliation: Department of Medicine, University of California, San Diego, CA, USA.
authors.forename: Davey M
authors.initials: DM
authors.lastname: Smith
authors.forename: Julie D
authors.initials: JD
authors.lastname: Kingery
authors.forename: Joseph K
authors.initials: JK
authors.lastname: Wong
authors.forename: Caroline C
authors.initials: CC
authors.lastname: Ignacio
authors.forename: Douglas D
authors.initials: DD
authors.lastname: Richman
authors.forename: Susan J
authors.initials: SJ
authors.lastname: Little
mesh_terms: D018592:Cross-Over Studies; D004197:Disease Reservoirs; D015658:HIV Infections / Q000635:transmission / Q000821:virology*; D015497:HIV-1; D006801:Humans; D008297:Male; D010808:Physical Examination; D011467:Prostate / Q000821:virology*; D011469:Prostatic Diseases / Q000821:virology*; D012367:RNA, Viral / Q000032:analysis; D012661:Semen / Q000737:chemistry / Q000821:virology
chemical_list: D012367:RNA, Viral