title: Comparison of the standard predictive equation for calculation of resting energy expenditure with indirect calorimetry in hospitalized and healthy dogs.
abstract: OBJECTIVE
  To determine the level of clinical agreement between 2 methods for the measurement of resting energy expenditure (REE).
  
  
  METHODS
  Prospective case series.
  
  
  METHODS
  77 dogs.
  
  
  METHODS
  Oxygen consumption (Vo2) and CO2 production (Vco2) were measured with an open-flow indirect calorimeter in healthy (n = 10) and ill (67) dogs. Measurements were collected at 3 time periods on 2 days. The Vo2 and the Vco2 measurements were then used to calculate the REE values.
  
  
  RESULTS
  Mean values of measured (MREE) and predicted (PREE) REEs in healthy dogs and a dog with medical illnesses or trauma were not significantly different. There was a significant difference on day 2 between the MREE and PREE in the group of dogs recovering from major surgery. More importantly, there was significant variation between the PREE and MREE on an individual-dog basis. The PREE only agreed to within +/- 20% of the MREE in 51% to 57% of the dogs.
  
  
  CONCLUSIONS
  The level of agreement between these two methods for determining the 24-hour REE was poor in individual dogs. The level of disagreement between the 2 methods indicates that these methods may not be used interchangeably in a clinical setting. Measurement of REE by use of indirect calorimetry may be the only reliable method of determining REE in an individual ill or healthy dog.
authors.affiliation: Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: O'Toole
authors.forename: Craig W
authors.initials: CW
authors.lastname: Miller
authors.forename: Brian A
authors.initials: BA
authors.lastname: Wilson
authors.forename: Karol A
authors.initials: KA
authors.lastname: Mathews
authors.forename: Clive
authors.initials: C
authors.lastname: Davis
authors.forename: William
authors.initials: W
authors.lastname: Sears
mesh_terms: D000818:Animals; D001481:Basal Metabolism / Q000502:physiology*; D002153:Calorimetry, Indirect / Q000379:methods / Q000662:veterinary*; D002245:Carbon Dioxide / Q000032:analysis / Q000378:metabolism; D016022:Case-Control Studies; D004283:Dog Diseases / Q000378:metabolism* / Q000601:surgery; D004285:Dogs / Q000378:metabolism* / Q000502:physiology; D005260:Female; D008297:Male; D010101:Oxygen Consumption; D011237:Predictive Value of Tests; D011446:Prospective Studies; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D002245:Carbon Dioxide