title: Persistent pulmonary hypertension late after neonatal aortic valvotomy: a consequence of an expanded surgical cohort.
abstract: BACKGROUND
  Survival of neonates with critical aortic stenosis has improved over the past decade. Models based on morphological characteristics have been designed to help determine whether early survival is more likely after biventricular repair (surgical or balloon aortic valvotomy) or after a single ventricle staged palliative surgical strategy. However, late follow up data are lacking.
  
  
  OBJECTIVE
  To report follow up data on survivors of neonatal aortic valvotomy who had persistent pulmonary hypertension caused by restriction to left ventricular filling.
  
  
  RESULTS
  Of four medium term survivors of neonatal valvotomy for critical aortic stenosis who had persistent pulmonary hypertension, one died aged 4 years and the other three have severe limitation of effort tolerance.
  
  
  CONCLUSIONS
  This previously unreported late complication of "successful" biventricular repair for neonatal critical aortic stenosis is an important consideration in determining the initial management.
authors.affiliation: Great Ormond Street Hospital for Children, Great Ormond Street, London WC1N 3JH, UK. burchm@gosh.nhs.uk
authors.forename: M
authors.initials: M
authors.lastname: Burch
authors.forename: L
authors.initials: L
authors.lastname: Kaufman
authors.forename: N
authors.initials: N
authors.lastname: Archer
authors.forename: I
authors.initials: I
authors.lastname: Sullivan
mesh_terms: D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging / Q000601:surgery*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology*; D007231:Infant, Newborn; D008297:Male; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000209:etiology*; D011247:Pregnancy; D016216:Ultrasonography, Prenatal