Callynormine A, a new marine cyclic peptide of a novel class.
[structure: see text] A novel cyclic peptide, callynormine A, was isolated from the Kenyan marine sponge Callyspongia abnormis and its structure elucidated by interpretation of its NMR data and X-ray diffraction analysis. Callynormine A represents a new class of heterodetic cyclic peptides (designated endiamino peptides) possessing an alpha-amido-beta-aminoacrylamide cyclization functionality.
Berer
Nelly
N
School of Chemistry and Department of Zoology, Tel-Aviv University, Ramat Aviv 69978, Israel.
Rudi
Amira
A
Goldberg
Israel
I
Benayahu
Yehuda
Y
Kashman
Yoel
Y
D000818:Animals; D047128:Callyspongia / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003500:Cyclization; D007630:Kenya; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010456:Peptides, Cyclic / Q000737:chemistry / Q000145:classification / Q000302:isolation & purification*; D013237:Stereoisomerism
D010456:Peptides, Cyclic; C495935:callynormine A