Effect of human pancreatic juice and bile on the tensile strength of suture materials.
BACKGROUND
Several suture materials are used for pancreatojejunal anastomosis. In this study, we tested the durability of these suture materials in human pancreatic juice and bile.


METHODS
Plain and chromic catgut, polyglactin 910, polyglycolic acid, polydioxanone, polypropylene, and silk sutures were incubated in pancreatic juice and bile that was collected from patients. Fifteen samples of each type of suture material were placed in human juices for 1, 3, and 7 days. Tensile strengths were measured with a tensionmeter.


RESULTS
Plain and chromic catgut disintegrated in pancreatic juice and pancreatic juice plus bile mixture. Polyglycolic acid and polyglactin 910 suture materials were vulnerable to pancreatic juice within 7 days. Polydioxanone retained most of its initial strength in pancreatic juice and bile. Polypropylene and silk retained 84% and 92% of their initial strength, respectively.


CONCLUSIONS
We found that polidioxanone was the strongest suture material in pancreatic juice.
Muftuoglu
M A Tolga
MA
Fourth General Surgical Department of Haydarpasa Numune Teaching and Training Hospital, Uskudar 34668, Istanbul, Turkey. tmuftuglu@ttnet.net.tr
Ozkan
Erkan
E
Saglam
Abdullah
A
D000714:Anastomosis, Surgical; D001646:Bile; D001672:Biocompatible Materials; D002398:Catgut; D006801:Humans; D007583:Jejunum / Q000601:surgery*; D008422:Materials Testing; D010179:Pancreas / Q000601:surgery*; D010189:Pancreatic Juice; D016687:Polydioxanone; D011098:Polyglactin 910; D011100:Polyglycolic Acid; D013537:Sutures; D013718:Tensile Strength
D001672:Biocompatible Materials; D011100:Polyglycolic Acid; D016687:Polydioxanone; D011098:Polyglactin 910