title: Impact of one year of shift work on cardiovascular disease risk factors.
abstract: The purpose of the study was to investigate whether the reported increased cardiovascular disease risk in shift workers could be explained by changes in cardiovascular risk factors. In a cohort of 239 shift and 157 daytime workers, 1-year changes in biological and lifestyle cardiovascular risk factors were monitored between the start of a new job and 1 year later. Both body mass index and low-density lipoprotein/high-density lipoprotein cholesterol ratio decreased significantly in shift workers compared with daytime workers (body mass index change: -0.31 and +0.13 kg/m; low-density lipoprotein/high-density lipoprotein ratio change: -0.33 and -0.13 respectively). Cigarettes smoked per day increased significantly in shift compared with daytime workers (+1.42 and -1.03, respectively). Therefore, only for smoking, an unfavorable change was observed. This may explain, at most, only a part of the excess cardiovascular disease risk reported in shift workers.
authors.affiliation: Department of Epidemiology, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The Netherlands. vanamelsvoort@epid.unimaas.nl
authors.forename: Ludovic G P M
authors.initials: LG
authors.lastname: van Amelsvoort
authors.forename: Evert G
authors.initials: EG
authors.lastname: Schouten
authors.forename: Frans J
authors.initials: FJ
authors.lastname: Kok
mesh_terms: D000328:Adult; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000209:etiology*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008019:Life Style; D008074:Lipoproteins / Q000097:blood; D008297:Male; D010561:Personnel Staffing and Scheduling; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects
chemical_list: D008074:Lipoproteins