title: Aberrant serum adiponectin levels in women with uterine leiomyomas.
abstract: BACKGROUND
  Adiponectin is an adipocyte-secreted hormone. Serum adiponectin levels are inversely correlated with insulin resistance, and low plasma adiponectin levels have been demonstrated in type 2 diabetic patients. However, information on serum adiponectin levels in gynecological disorders is mostly lacking. In this study, we analyzed the possible correlation between serum adiponectin levels and uterine leiomyomas.
  
  
  METHODS
  Serum adiponectin levels, determined by radioimmunoassay, were compared in women with uterine leiomyomas (n = 47) and normal controls (n = 46).
  
  
  RESULTS
  Serum adiponectin levels in women with uterine leiomyomas (16.4 +/- 0.9 microg/ml) were significantly lower (p < 0.05) than those in the normal controls (19.5 +/- 1.0 microg/ml). Furthermore, there was an inverse correlation between serum adiponectin levels and body mass index, in both women with leiomyomas and normal controls.
  
  
  CONCLUSIONS
  Serum adiponectin levels are significantly decreased in myomatous patients.
authors.affiliation: Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, ROC.
authors.forename: Hung-Sheng
authors.initials: HS
authors.lastname: Chen
authors.forename: Te-Fu
authors.initials: TF
authors.lastname: Chan
authors.forename: Yueh-Fang
authors.initials: YF
authors.lastname: Chung
authors.forename: Jinu-Huang
authors.initials: JH
authors.lastname: Su
authors.forename: Shyng-Shiou F
authors.initials: SS
authors.lastname: Yuan
mesh_terms: D052242:Adiponectin; D000328:Adult; D015992:Body Mass Index; D016022:Case-Control Studies; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007044:Hysterectomy; D007333:Insulin Resistance / Q000502:physiology; D036341:Intercellular Signaling Peptides and Proteins / Q000097:blood*; D007889:Leiomyoma / Q000097:blood* / Q000601:surgery; D016014:Linear Models; D011863:Radioimmunoassay; D014594:Uterine Neoplasms / Q000097:blood* / Q000601:surgery
chemical_list: D052242:Adiponectin; D006454:Hemoglobins; D036341:Intercellular Signaling Peptides and Proteins