title: Markedly asymmetrical parkinsonism as a leading feature of adult-onset Huntington's disease.
abstract: We report on a 28-year-old man who presented with right hand tremor, bradykinesia, and rigidity of his right side extremities. Our case report emphasizes that markedly asymmetrical parkinsonism can be an initial presentation of adult-onset Huntington's disease (HD), and different clinical presentations can be observed in members of an individual HD family with the same CAG repeat length.
authors.affiliation: Second Department of Neurology, Chang Gung Memorial Hospital, LinKou Medical Center, Taipei, Taiwan.
authors.forename: Shih-Ching
authors.initials: SC
authors.lastname: Wang
authors.affiliation: Department of Life Science, National Taiwan Normal University, Taipei, Taiwan.
authors.forename: Guey-Jen
authors.initials: GJ
authors.lastname: Lee-Chen
authors.affiliation: Department of Life Science, National Taiwan Normal University, Taipei, Taiwan.|Jen-Teh Junior College of Medicine, Nursing and Management, Miaoli, Taiwan.
authors.forename: Cheng-Kung
authors.initials: CK
authors.lastname: Wang
authors.affiliation: Second Department of Neurology, Chang Gung Memorial Hospital, LinKou Medical Center, Taipei, Taiwan.
authors.forename: Chiung-Mei
authors.initials: CM
authors.lastname: Chen
authors.affiliation: Second Department of Neurology, Chang Gung Memorial Hospital, LinKou Medical Center, Taipei, Taiwan.
authors.forename: Lok-Ming
authors.initials: LM
authors.lastname: Tang
authors.affiliation: Second Department of Neurology, Chang Gung Memorial Hospital, LinKou Medical Center, Taipei, Taiwan.
authors.forename: Yih-Ru
authors.initials: YR
authors.lastname: Wu
mesh_terms: D000328:Adult; D000483:Alleles; D000978:Antiparkinson Agents / Q000627:therapeutic use; D002230:Carbidopa / Q000627:therapeutic use; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology; D003937:Diagnosis, Differential; D004338:Drug Combinations; D006801:Humans; D006816:Huntington Disease / Q000150:complications / Q000175:diagnosis* / Q000235:genetics*; D007980:Levodopa / Q000627:therapeutic use; D008297:Male; D009483:Neuropsychological Tests; D020734:Parkinsonian Disorders / Q000175:diagnosis* / Q000188:drug therapy; D010375:Pedigree; D012720:Severity of Illness Index
chemical_list: D000978:Antiparkinson Agents; D004338:Drug Combinations; C009265:carbidopa, levodopa drug combination; D007980:Levodopa; D002230:Carbidopa