title: A set of BAC clones spanning the human genome.
abstract: Using the human bacterial artificial chromosome (BAC) fingerprint-based physical map, genome sequence assembly and BAC end sequences, we have generated a fingerprint-validated set of 32 855 BAC clones spanning the human genome. The clone set provides coverage for at least 98% of the human fingerprint map, 99% of the current assembled sequence and has an effective resolving power of 79 kb. We have made the clone set publicly available, anticipating that it will generally facilitate FISH or array-CGH-based identification and characterization of chromosomal alterations relevant to disease.
authors.affiliation: BC Cancer Agency Genome Sciences Center and BC Cancer Agency, Vancouver, BC V5Z 4E6, Canada.
authors.forename: Martin
authors.initials: M
authors.lastname: Krzywinski
authors.forename: Ian
authors.initials: I
authors.lastname: Bosdet
authors.forename: Duane
authors.initials: D
authors.lastname: Smailus
authors.forename: Readman
authors.initials: R
authors.lastname: Chiu
authors.forename: Carrie
authors.initials: C
authors.lastname: Mathewson
authors.forename: Natasja
authors.initials: N
authors.lastname: Wye
authors.forename: Sarah
authors.initials: S
authors.lastname: Barber
authors.forename: Mabel
authors.initials: M
authors.lastname: Brown-John
authors.forename: Susanna
authors.initials: S
authors.lastname: Chan
authors.forename: Steve
authors.initials: S
authors.lastname: Chand
authors.forename: Alison
authors.initials: A
authors.lastname: Cloutier
authors.forename: Noreen
authors.initials: N
authors.lastname: Girn
authors.forename: Darlene
authors.initials: D
authors.lastname: Lee
authors.forename: Amara
authors.initials: A
authors.lastname: Masson
authors.forename: Michael
authors.initials: M
authors.lastname: Mayo
authors.forename: Teika
authors.initials: T
authors.lastname: Olson
authors.forename: Pawan
authors.initials: P
authors.lastname: Pandoh
authors.forename: Anna-Liisa
authors.initials: AL
authors.lastname: Prabhu
authors.forename: Eric
authors.initials: E
authors.lastname: Schoenmakers
authors.forename: Miranda
authors.initials: M
authors.lastname: Tsai
authors.forename: Donna
authors.initials: D
authors.lastname: Albertson
authors.forename: Wan
authors.initials: W
authors.lastname: Lam
authors.forename: Chik-On
authors.initials: CO
authors.lastname: Choy
authors.forename: Kazutoyo
authors.initials: K
authors.lastname: Osoegawa
authors.forename: Shaying
authors.initials: S
authors.lastname: Zhao
authors.forename: Pieter J
authors.initials: PJ
authors.lastname: de Jong
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Schein
authors.forename: Steven
authors.initials: S
authors.lastname: Jones
authors.forename: Marco A
authors.initials: MA
authors.lastname: Marra
mesh_terms: D001483:Base Sequence; D022202:Chromosomes, Artificial, Bacterial; D003001:Cloning, Molecular; D015894:Genome, Human; D006801:Humans; D020161:Physical Chromosome Mapping