title: Erasing restylane.
abstract: A 65-year-old woman received injections of Restylane, cross-linked hyaluronic acid, for the intended cosmetic filling of periorbital rhytids. The achieved result was undesirable, and the filler lasted more than 5 years. Hyaluronidase administered directly beneath the treated areas resulted in rapid resolution of the Restylane effect.
authors.affiliation: Plastic Eye Surgery Associates, PLLC, 6655 Travis Street, Houston, TX 77030, U.S.A. pesa_2004@sbcglobal.net
authors.forename: Charles N S
authors.initials: CN
authors.lastname: Soparkar
authors.forename: James R
authors.initials: JR
authors.lastname: Patrinely
authors.forename: Jamie
authors.initials: J
authors.lastname: Tschen
mesh_terms: D000368:Aged; D003357:Cosmetic Techniques / Q000009:adverse effects; D005145:Face; D005260:Female; D015745:Granuloma, Foreign-Body / Q000139:chemically induced / Q000188:drug therapy*; D006801:Humans; D006820:Hyaluronic Acid / Q000009:adverse effects* / Q000031:analogs & derivatives*; D006821:Hyaluronoglucosaminidase / Q000008:administration & dosage / Q000627:therapeutic use*; D007267:Injections; D009915:Orbit; D015595:Skin Aging
chemical_list: D006820:Hyaluronic Acid; D006821:Hyaluronoglucosaminidase; C445361:Restylane