title: Extending the window for acute stroke treatment: thrombolytics plus CNS protective therapies.
authors.affiliation: Department of Neurology, University of Cincinnati College of Medicine, OH 45267, USA. wagnerkr@email.uc.edu
authors.forename: Kenneth R
authors.initials: KR
authors.lastname: Wagner
authors.forename: Edward C
authors.initials: EC
authors.lastname: Jauch
mesh_terms: D000208:Acute Disease; D000818:Animals; D001557:Benzenesulfonates; D002490:Central Nervous System / Q000187:drug effects*; D002543:Cerebral Hemorrhage / Q000139:chemically induced / Q000517:prevention & control; D004195:Disease Models, Animal; D004359:Drug Therapy, Combination; D005343:Fibrinolytic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D016166:Free Radical Scavengers / Q000627:therapeutic use*; D006801:Humans; D007036:Hypothermia, Induced / Q000639:trends; D018696:Neuroprotective Agents / Q000009:adverse effects / Q000494:pharmacology*; D009589:Nitrogen Oxides / Q000494:pharmacology; D018384:Oxidative Stress / Q000187:drug effects; D020521:Stroke / Q000188:drug therapy / Q000628:therapy*; D000077785:Tenecteplase; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D001557:Benzenesulfonates; D005343:Fibrinolytic Agents; D016166:Free Radical Scavengers; D018696:Neuroprotective Agents; D009589:Nitrogen Oxides; C120851:disufenton sodium; D010959:Tissue Plasminogen Activator; D000077785:Tenecteplase