Developmental differences in nicotine place conditioning.
To understand the motivations and implications of the prevalence of smoking, studies have compared the behavioral effects of nicotine, the psychoactive drug in tobacco, in adolescent and adult animals. The present study used a biased three-chambered conditioned-place preference procedure without prior habituation to examine the potential rewarding and anxiolytic effects of nicotine across adolescence and adulthood to assess the presence of age-dependent differences in response to nicotine.
Torrella
Tracy A
TA
Department of Pharmacology and Therapeutics, USFCOM, MDC Box 9, 12901 Bruce B. Downs Boulevard, Tampa, FL 33612-4799, USA. lwecker@hsc.usf.edu
Badanich
Kimberly A
KA
Philpot
Rex M
RM
Kirstein
Cheryl L
CL
Wecker
Lynn
L
D000367:Age Factors; D000704:Analysis of Variance; D000818:Animals; D000831:Animals, Newborn; D001522:Behavior, Animal; D002755:Choice Behavior / Q000187:drug effects; D003216:Conditioning, Operant / Q000187:drug effects*; D005260:Female; D008297:Male; D009042:Motivation; D009538:Nicotine / Q000494:pharmacology*; D018722:Nicotinic Agonists / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley
D018722:Nicotinic Agonists; D009538:Nicotine