Putting a brake on an autonomous DNA nanomotor.
A strategy was developed to reversibly switch on/off an autonomous DNA nanomotor that contains a DNA enzyme. The multiple RNA cleavage of the DNAzyme powered the motor to move, and a strand displacement mechanism provided the basis for a reversible brake to the motor.
Chen
Yi
Y
Department of Chemistry, Purdue University, West Lafayette, Indiana 47906, USA.
Mao
Chengde
C
D004247:DNA / Q000737:chemistry* / Q000187:drug effects* / Q000502:physiology; D020409:Molecular Motor Proteins / Q000737:chemistry* / Q000187:drug effects* / Q000502:physiology; D036103:Nanotechnology / Q000379:methods*; D009696:Nucleic Acids / Q000494:pharmacology*; D013050:Spectrometry, Fluorescence
D020409:Molecular Motor Proteins; D009696:Nucleic Acids; D004247:DNA