title: Effect of sildenafil citrate on retinal functions: preliminary report on Humphrey visual field analysis.
abstract: OBJECTIVE
  To assess the effect of sildenafil citrate treatment on visual field analysis (VFA) in patients using sildenafil citrate for erectile dysfunction.
  
  
  METHODS
  In this prospective study on 18 male volunteers with erectile dysfunction, bilateral VFA was performed using the Humphrey 30-2 central standard threshold test. White-on-white (W/W) and blue-on-yellow (B/Y) protocols were used prior to treatment (baseline VFA) and after treatment (repeat VFA) with sildenafil citrate. W/W and B/Y baseline VFA and repeat VFA mean deviations (MD) were compared.
  
  
  RESULTS
  The baseline MD for W/W and B/Y protocols were -1.34 +/- 1.8 and -2.59 +/- 2.1 dB, respectively, whereas the mean repeat MD for W/W and B/Y protocols were -1.79 +/- 2.21 and -2.83 +/- 3.31 dB, respectively. There was no statistically significant difference between W/W and B/Y baseline and repeat VFA with respect to MD (p > 0.05).
  
  
  CONCLUSIONS
  Sildenafil citrate causes no significant changes in Humphrey VFA in patients with erectile dysfunction.
authors.affiliation: Department of Ophthalmology, Dokuz Eylül University School of Medicine, Izmir, Turkey.
authors.forename: Hakan F
authors.initials: HF
authors.lastname: Oner
authors.forename: Güven
authors.initials: G
authors.lastname: Aslan
authors.forename: Erkan
authors.initials: E
authors.lastname: Kurtulan
authors.forename: Tolga
authors.initials: T
authors.lastname: Uçar
authors.forename: Osman A
authors.initials: OA
authors.lastname: Saatçi
authors.forename: Adil A
authors.initials: AA
authors.lastname: Esen
mesh_terms: D000328:Adult; D007172:Erectile Dysfunction / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010726:Phosphodiesterase Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D010879:Piperazines / Q000494:pharmacology* / Q000627:therapeutic use; D011446:Prospective Studies; D011687:Purines; D012160:Retina / Q000187:drug effects*; D000068677:Sildenafil Citrate; D013450:Sulfones; D014787:Vision Tests / Q000379:methods; D014794:Visual Fields / Q000187:drug effects
chemical_list: D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D000068677:Sildenafil Citrate