Lipoic acid as a potential first agent for protection from mycotoxins and treatment of mycotoxicosis.
Mycotoxins--toxic substances produced by fungi or molds--are ubiquitous in the environment and are capable of damaging multiple biochemical mechanisms, resulting in a variety of human symptoms referred to collectively as "mycotoxicosis." In fact, mycotoxins mimic multiple xenobiotics, not only with respect to their ultimate damage, but also in their routes of detoxification. This suggests potential therapeutic options for the challenging treatment of mycotoxicosis. In this brief review, the author examines the use of lipoic acid as an example of an inexpensive and available nutrient that has been shown to protect against, or reverse, the adverse health effects of mycotoxins.
Rogers
Sherry A
SA
Northeast Center for Environmental Medicine, Sarasota, Florida, USA.
D016902:Air Pollution, Indoor / Q000009:adverse effects / Q000517:prevention & control; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology / Q000627:therapeutic use*; D035843:Biomedical Research; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D006801:Humans; D019570:Inhalation Exposure / Q000009:adverse effects / Q000517:prevention & control; D015651:Mycotoxicosis / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D009183:Mycotoxins / Q000009:adverse effects*; D018877:Sick Building Syndrome / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D008063:Thioctic Acid / Q000494:pharmacology / Q000627:therapeutic use*; D015262:Xenobiotics / Q000009:adverse effects
D000975:Antioxidants; D009183:Mycotoxins; D015262:Xenobiotics; D008063:Thioctic Acid