title: Case of cryptic malaria.
abstract: We report a case of falciparum malaria in a renal transplant patient with no history of foreign travel. Three weeks previously she had been a hospital inpatient with cellulitis and had stayed on the same ward as a man with falciparum malaria acquired in Nigeria. There were no cases of malaria in other patients on the ward at the same time. The parasites from the two cases were genotypically indistinguishable. Despite a thorough investigation, reviewed by an expert external panel, no clear route of infection between the cases was identified. Patients with malaria should be considered highly infectious by the parenteral route. They should be managed with the infection control precautions used for patients with bloodborne virus infections. Our case reinforces the need for high levels of compliance with universal infection control procedures.
authors.affiliation: John Radcliffe Hospital, Oxford. ed@moran.org
authors.forename: E
authors.initials: E
authors.lastname: Moran
authors.forename: L
authors.initials: L
authors.lastname: Collins
authors.forename: S
authors.initials: S
authors.lastname: Clayton
authors.forename: T
authors.initials: T
authors.lastname: Peto
authors.forename: I C J W
authors.initials: IC
authors.lastname: Bowler
mesh_terms: D000328:Adult; D000818:Animals; D000962:Antimalarials / Q000008:administration & dosage / Q000627:therapeutic use; D017848:Blood-Borne Pathogens; D016358:Contact Tracing; D003428:Cross Infection / Q000469:parasitology* / Q000517:prevention & control / Q000635:transmission*; D005260:Female; D006757:Hospital Units / Q000592:standards*; D006801:Humans; D017053:Infection Control / Q000592:standards*; D016030:Kidney Transplantation; D016778:Malaria, Falciparum / Q000175:diagnosis / Q000188:drug therapy / Q000517:prevention & control* / Q000635:transmission*; D009549:Nigeria; D010963:Plasmodium falciparum / Q000302:isolation & purification* / Q000472:pathogenicity; D011803:Quinine / Q000008:administration & dosage / Q000627:therapeutic use; D006113:United Kingdom
chemical_list: D000962:Antimalarials; D011803:Quinine