title: Branches on the alpha-C atom of cyclosporin A residue 3 result in direct calcineurin inhibition and rapid cyclophilin 18 binding.
authors.affiliation: Max Planck Research Unit for Enzymology of Protein Folding, Weinbergweg 22, 06120, Halle/Saale, Germany.
authors.forename: Yixin
authors.initials: Y
authors.lastname: Zhang
authors.forename: Ria
authors.initials: R
authors.lastname: Baumgrass
authors.forename: Ria
authors.initials: R
authors.lastname: Raumgrass
authors.forename: Mike
authors.initials: M
authors.lastname: Schutkowski
authors.forename: Gunter
authors.initials: G
authors.lastname: Fischer
mesh_terms: D019703:Calcineurin / Q000378:metabolism; D065095:Calcineurin Inhibitors; D021983:Cyclophilins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D016572:Cyclosporine / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D008958:Models, Molecular; D011485:Protein Binding
chemical_list: D065095:Calcineurin Inhibitors; D016572:Cyclosporine; D019703:Calcineurin; D021983:Cyclophilins