title: Unrecognised tuberculosis in HIV-infected patients: sputum culture is a useful tool.
abstract: Diagnosis of tuberculosis is challenging, especially in human immunodeficiency virus (HIV) positive persons who may have atypical clinical and radiographic features. We report the isolation of Mycobacterium tuberculosis from sputum samples of 10 (4%) HIV-positive persons who were asymptomatic with normal chest radiographs and negative sputum smears for acid-fast bacilli. Six of them had strongly positive tuberculin reactions while four were severely immunosuppressed. Our observation highlights the utility of routine sputum culture in the diagnosis of tuberculosis in high-risk individuals.
authors.affiliation: Division of HIV/AIDS, Tuberculosis Research Centre, Chennai, Tamil Nadu, India. doctorsoumya@yahoo.com
authors.forename: S
authors.initials: S
authors.lastname: Swaminathan
authors.forename: C N
authors.initials: CN
authors.lastname: Paramasivan
authors.forename: S R
authors.initials: SR
authors.lastname: Kumar
authors.forename: V
authors.initials: V
authors.lastname: Mohan
authors.forename: P
authors.initials: P
authors.lastname: Venkatesan
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D013902:Radiography, Thoracic; D013183:Sputum / Q000166:cytology*; D014374:Tuberculin Test; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000821:virology