title: Rapid reversal of global left ventricular dysfunction after accidental injection of 0.75 mg epinephrine in a 20-year-old patient.
abstract: We report an accidental injection of epinephrine before spinal anaesthesia in a 20-year-old patient who subsequently developed immediate myocardial ischemia and global left ventricular dysfunction (ejection fraction of 20%). Hemodynamic status dramatically improved after nitroglycerin, calcium antagonists, acetyl salicylic acid and unfractionated heparin injections. Over 24 h, patient's ejection fraction fully recovered without kinetic abnormality.
authors.affiliation: Department of Anaesthesia, Military Teaching Hospital, Hopital d'Instruction des Armees Sainte Anne, Toulon-Naval, France. meaudre@club-internet.fr
authors.forename: E
authors.initials: E
authors.lastname: Meaudre
authors.forename: F
authors.initials: F
authors.lastname: Barbou
authors.forename: M
authors.initials: M
authors.lastname: Sallaberry
authors.forename: E
authors.initials: E
authors.lastname: Cantais
authors.forename: D
authors.initials: D
authors.lastname: Petit
authors.forename: B
authors.initials: B
authors.lastname: Palmier
mesh_terms: D000328:Adult; D004837:Epinephrine / Q000009:adverse effects*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D018487:Ventricular Dysfunction, Left / Q000139:chemically induced* / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D004837:Epinephrine