title: Quantitative characterization of edge enhancement in phase contrast x-ray imaging.
abstract: The aim of this study was to model the edge enhancement effect in in-line holography phase contrast imaging. A simple analytical approach was used to quantify refraction and interference contrasts in terms of beam energy and imaging geometry. The model was applied to predict the peak intensity and frequency of the edge enhancement for images of cylindrical fibers. The calculations were compared with measurements, and the relationship between the spatial resolution of the detector and the amplitude of the phase contrast signal was investigated. Calculations using the analytical model were in good agreement with experimental results for nylon, aluminum and copper wires of 50 to 240 microm diameter, and with numerical simulations based on Fresnel-Kirchhoff theory. A relationship between the defocusing distance and the pixel size of the image detector was established. This analytical model is a useful tool for optimizing imaging parameters in phase contrast in-line holography, including defocusing distance, detector resolution and beam energy.
authors.affiliation: Institut Universitaire de Radiophysique Appliquée (IRA), Grand-Pré 1, CH-1007 Lausanne, Switzerland. pascal.monnin@inst.hospvd.ch
authors.forename: P
authors.initials: P
authors.lastname: Monnin
authors.forename: S
authors.initials: S
authors.lastname: Bulling
authors.forename: J
authors.initials: J
authors.lastname: Hoszowska
authors.forename: J F
authors.initials: JF
authors.lastname: Valley
authors.forename: R
authors.initials: R
authors.lastname: Meuli
authors.forename: F R
authors.initials: FR
authors.lastname: Verdun
mesh_terms: D055592:Biophysical Phenomena; D001703:Biophysics; D006696:Holography; D006801:Humans; D008962:Models, Theoretical; D055095:Optics and Photonics; D011857:Radiographic Image Interpretation, Computer-Assisted; D017356:Synchrotrons; D014961:X-Ray Diffraction