DNMAD: web-based diagnosis and normalization for microarray data.
CONCLUSIONS
We present a web server for Diagnosis and Normalization of MicroArray Data (DNMAD). DNMAD includes several common data transformations such as spatial and global robust local regression or multiple slide normalization, and allows for detecting several kinds of errors that result from the manipulation and the image analysis of the arrays. This tool offers a user-friendly interface, and is completely integrated within the Gene Expression Pattern Analysis Suite (GEPAS).


BACKGROUND
The tool is accessible on-line at http://dnmad.bioinfo.cnio.es.
Vaquerizas
Juan M
JM
Bioinformatics Unit, CNIO, Spanish National Cancer Centre, Melchor Fernández Almagro 3, 28029 Madrid, Spain.
Dopazo
Joaquín
J
Díaz-Uriarte
Ramón
R
D000465:Algorithms; D003628:Database Management Systems; D020869:Gene Expression Profiling / Q000379:methods* / Q000592:standards; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods* / Q000592:standards; D016415:Sequence Alignment / Q000379:methods; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D014584:User-Computer Interface