Detection of renal cell carcinoma-associated markers via proteome- and other 'ome'-based analyses.
Proteome analysis has rapidly developed in the post-genome era and is now widely accepted as the complementary technology for genetic profiling. It has been shown to be a powerful tool for studying human diseases and for identifying novel prognostic, diagnostic and therapeutic markers. This review focuses on the identification of new biomarkers and therapeutic targets for renal cell carcinoma using different 'ome'-based technologies.
Seliger
Barbara
B
Third Department of Internal Medicine at the Johannes Gutenberg University, Mainz, Germany. 3-med.klinik.uni-mainz.de
Lichtenfels
Rudolf
R
Kellner
Roland
R
D014408:Biomarkers, Tumor / Q000235:genetics*; D002292:Carcinoma, Renal Cell / Q000175:diagnosis* / Q000235:genetics; D015180:Electrophoresis, Gel, Two-Dimensional; D020869:Gene Expression Profiling; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000235:genetics; D013058:Mass Spectrometry; D040081:Protein Array Analysis; D020543:Proteome / Q000032:analysis*; D040901:Proteomics / Q000379:methods
D014408:Biomarkers, Tumor; D020543:Proteome