title: The serological and genetic basis of the cis-AB blood group in Korea.
abstract: OBJECTIVE
  The cis-AB blood group is rare, although relatively common amongst Koreans. The serological characteristics and genetic basis of Korean cis-AB blood donors were investigated.
  
  
  METHODS
  Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), designed to detect the cis-AB01 allele, was performed on 194 AB samples which demonstrated weak or unusual expression of either or both of the A or B antigens.
  
  
  CONCLUSIONS
  Sixty cis-AB01 donors were identified. cis-AB01/O01 or O02 were the most common genotypes (36/60) detected only in A(2)B(3) donors, and cis-AB01/B101 (nine of 60) was the least common genotype identified only in A(2)B donors. Surprisingly cis-AB01/A102 (15/60) was identified in a variety of phenotypes (A(1)B(3), A(1)B(x) or el, A(int)B(3)).
authors.affiliation: Department of Laboratory Medicine, Chonnam National University Hospital, Gwangju, South Korea.
authors.forename: D
authors.initials: D
authors.lastname: Cho
authors.forename: S-H
authors.initials: SH
authors.lastname: Kim
authors.forename: M-J
authors.initials: MJ
authors.lastname: Jeon
authors.forename: K-L
authors.initials: KL
authors.lastname: Choi
authors.forename: S-J
authors.initials: SJ
authors.lastname: Kee
authors.forename: M-G
authors.initials: MG
authors.lastname: Shin
authors.forename: J-H
authors.initials: JH
authors.lastname: Shin
authors.forename: S-P
authors.initials: SP
authors.lastname: Suh
authors.forename: M H
authors.initials: MH
authors.lastname: Yazer
authors.forename: D-W
authors.initials: DW
authors.lastname: Ryang
mesh_terms: D000017:ABO Blood-Group System / Q000032:analysis / Q000235:genetics* / Q000276:immunology; D000483:Alleles; D001782:Blood Donors; D005700:Galactosyltransferases; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D007723:Korea; D017350:N-Acetylgalactosaminyltransferases; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D000017:ABO Blood-Group System; D005700:Galactosyltransferases; D017350:N-Acetylgalactosaminyltransferases; C003742:UDPgalactosamine-galactose acetylgalactosaminyltransferase; C023155:blood-group-substance alpha-D-galactosyltransferase