title: The IUBMB-endorsed transporter classification system.
abstract: We here describe the transporter classification (TC) system that provides a rational means of classifying all transmembrane transport systems found in living organisms. The availability of this system provides a framework for the use of bioinformatic technologies to answer fundamental questions about the functions, mechanisms, and evolutionary pathways taken for the appearance of these systems. Such advances are discussed.
authors.affiliation: Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Busch
authors.forename: Milton H
authors.initials: MH
authors.lastname: Saier
mesh_terms: D000595:Amino Acid Sequence; D001671:Biochemistry / Q000379:methods / Q000592:standards*; D030562:Databases, Protein / Q000592:standards*; D004282:Documentation / Q000379:methods*; D019143:Evolution, Molecular; D017408:Guidelines as Topic; D038622:Internationality; D026901:Membrane Transport Proteins / Q000737:chemistry* / Q000145:classification* / Q000592:standards; D008967:Molecular Biology / Q000379:methods / Q000592:standards*; D008969:Molecular Sequence Data; D009626:Terminology as Topic; D018875:Vocabulary, Controlled
chemical_list: D026901:Membrane Transport Proteins