title: Preparations and spectroscopic studies of organotin complexes of diclofenac.
abstract: The reactions of the potent and widely used anti-inflammatory drug diclofenac, HL, with diorganotin(IV) oxides were studied. The dimeric tetraorganodistannoxane complexes [Me(2)LSnOSnLMe(2)](2), [Bu(2)LSnOSnLBu(2)](2), [Ph(2)LSnOSnLPh(2)](2) and the dibutyltin complex [Bu(2)SnL(2)], have been prepared and structurally characterized in the solid state by means of vibrational and 119Sn Mössbauer spectroscopy. Determination of lattice dynamics by temperature-dependent 119Sn Mössbauer spectroscopy. From the variable-temperature Mössbauer effect, the Debye temperature was determined. The complexes have been characterized in solution by NMR (1H and 13C) spectroscopy. Vibrational, Mössbauer, and NMR data are discussed in terms of the proposed structures.
authors.affiliation: Inorganic and Analytical Chemistry, Department of Chemistry, University of Ioannina, 45100 Ioannina, Greece.
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Kourkoumelis
authors.forename: Mavroudis A
authors.initials: MA
authors.lastname: Demertzis
authors.forename: Dimitra
authors.initials: D
authors.lastname: Kovala-Demertzi
authors.forename: Aglaia
authors.initials: A
authors.lastname: Koutsodimou
authors.forename: Alice
authors.initials: A
authors.lastname: Moukarika
mesh_terms: D002247:Carbon Isotopes; D004008:Diclofenac / Q000138:chemical synthesis / Q000737:chemistry*; D006859:Hydrogen; D009682:Magnetic Resonance Spectroscopy; D009947:Organotin Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D013055:Spectrophotometry, Infrared
chemical_list: D002247:Carbon Isotopes; D009947:Organotin Compounds; D004008:Diclofenac; D006859:Hydrogen