Vaginal and cervical atresia in a cynomolgus macaque.
A female cynomolgus monkey presented clinically with a caudal abdominal mass noted on a prestudy physical examination. No other clinical abnormalities were noted. An ultrasound examination revealed a mass approximately 2 cm in diameter, which contained fluid with a granular "free-floating" appearance. Within a month the mass enlarged and was visible from external examination. Exploratory laparotomy revealed a mass encompassing the uterus, both ovaries, bladder, and rectum. The animal was euthanized under anesthesia, and the mass was removed, examined, and submitted for histopathology. A diagnosis of vaginal and cervical atresia was made. To the author's knowledge, this is the first description of vaginal and cervical atresia in a laboratory nonhuman primate.
Laffins
Michael M
MM
Charles River Laboratories, Sierra Division, Sparks, Nevada 587 Dunn Circle Sparks, Nevada 89431, USA.
Andrews-Jones
Lydia
L
D000818:Animals; D002584:Cervix Uteri / Q000002:abnormalities*; D017809:Fatal Outcome; D005260:Female; D005831:Genital Diseases, Female / Q000473:pathology / Q000662:veterinary*; D008252:Macaca fascicularis; D008992:Monkey Diseases / Q000473:pathology*; D014621:Vagina / Q000002:abnormalities*