title: Double C-H activation during functionalization of phenyl(methyl)ketene on iridium(I) using alkynes. synthesis of 1,4-dien-3-ones.
abstract: Under the influence of an Ir(I) metal fragment, the methyl group of phenyl(methyl)ketene undergoes two C-H activations in reacting with internal alkynes, giving metallacycles 3 in 86-94% yield. Treatment of 3 with CO liberates 1,4-dien-3-ones 5 in 81-93% yield, along with CO complex 4. A possible mechanism for the very selective double C-H activation-alkyne coupling is discussed.
authors.affiliation: Department of Chemistry, San Diego State University, 5500 Campanile Drive, San Diego, California 92182-1030, USA. grotjahn@chemistry.sdsu.edu
authors.forename: Douglas B
authors.initials: DB
authors.lastname: Grotjahn
authors.forename: Justin M
authors.initials: JM
authors.lastname: Hoerter
authors.forename: John L
authors.initials: JL
authors.lastname: Hubbard