title: Verteporfin photodynamic therapy for extrafoveal choroidal neovascularisation in pathologic myopia.
abstract: BACKGROUND
  To report long-term functional and morphological outcome of verteporfin photodynamic therapy (PDT) for classic extrafoveal choroidal neovascularisation (CNV) secondary to pathologic myopia.
  
  
  METHODS
  This retrospective case series included three eyes of three consecutive patients with classic extrafoveal CNV secondary to pathologic myopia, who underwent PDT at a tertiary retinal referral centre. Change in visual acuity and fluorescein leakage was the main outcome criteria.
  
  
  RESULTS
  The patients were followed up an average of 36 months (33-40 months). In all eyes increase of visual acuity (one eye 1 ETDRS line, two eyes 2 ETDRS line) and no fluorescein leakage of the CNV were seen.
  
  
  CONCLUSIONS
  PDT can achieve long-term improvement of the visual acuity and morphological stability in selected cases with classic extrafoveal CNV in pathologic myopia. Large scale randomised studies are warranted for assessment of the benefit of PDT in such eyes.
authors.affiliation: Department of Ophthalmology I, University of Tuebingen, Schleichstr. 12, 72076, Tuebingen, Germany. faik.gelisken@med.uni-tuebingen.de
authors.forename: Faik
authors.initials: F
authors.lastname: Gelisken
authors.forename: Werner
authors.initials: W
authors.lastname: Inhoffen
authors.forename: Alexander
authors.initials: A
authors.lastname: Hermann
authors.forename: Salvatore
authors.initials: S
authors.lastname: Grisanti
authors.forename: Karl Ulrich
authors.initials: KU
authors.lastname: Bartz-Schmidt
mesh_terms: D000328:Adult; D020256:Choroidal Neovascularization / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000150:complications*; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D011166:Porphyrins / Q000627:therapeutic use*; D012189:Retrospective Studies; D000077362:Verteporfin; D014792:Visual Acuity
chemical_list: D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin