Chorea-acanthocytosis associated with Tourettism.
We report on a case of Chorea-acanthocytosis (ChAc) in association with Tourettism that consisted of motor and vocal tics, attention deficit-hyperactivity disorder, and obsessive-compulsive disorder in addition to the typical symptoms of ChAc. The subject was compared with his elder sister who had the same disease but milder clinical profile and neuroradiological findings. The [(18)F]-2-fluoro-2-deoxyglucose positron emission tomography (FDG-PET) findings did not explain the differences in symptomatology between the patient and his sister, although they may have correlated with severity.
Saiki
Shinji
S
Department of Neurology, Kanazawa Medical University, Ishikawa, Japan.
Hirose
Genjiro
G
Department of Neurology, Kanazawa Medical University, Ishikawa, Japan.
Sakai
Koichiro
K
Department of Neurology, Kanazawa Medical University, Ishikawa, Japan.
Matsunari
Ichiro
I
The Medical and Pharmacological Research Center Foundation, Ishikawa, Japan.
Higashi
Kotaro
K
Department of Radiology, Kanazawa Medical University, Ishikawa, Japan.
Saiki
Misuzu
M
Department of Neurology, Kanazawa Medical University, Ishikawa, Japan.
Kataoka
Satoshi
S
Department of Neurology, Kanazawa Medical University, Ishikawa, Japan.
Hori
Ariyuki
A
Department of Neurology, Kanazawa Medical University, Ishikawa, Japan.
Shimazaki
Kohei
K
Department of Internal Medicine, Hamano-nishi Hospital, Ishikawa, Japan.
D000328:Adult; D001289:Attention Deficit Disorder with Hyperactivity / Q000150:complications; D002819:Chorea / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism*; D003342:Corpus Striatum / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D003704:Dementia / Q000150:complications / Q000175:diagnosis; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D019275:Radiopharmaceuticals; D013064:Speech Disorders / Q000150:complications; D014055:Tomography, Emission-Computed; D005879:Tourette Syndrome / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism*
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18