title: Short communication: influence of Staphylococcus aureus intramammary infection on serum copper, zinc, and iron concentrations.
abstract: The goal of the present study was to characterize changes in serum trace mineral concentrations in cattle with experimentally induced Staphylococcus aureus mastitis. Nine primiparous Holstein-Friesian cattle were challenged with approximately 150 cfu of Staph. aureus ATCC29740 by intramammary infusion on d 6, 7, and 8 of lactation. Serum Cu, Zn, and Fe concentrations were determined immediately before and at 24, 48, and 72 h after the final intramammary infusion of Staph. aureus. Infection status (cfu/mL of Staph. aureus), milk somatic cell count, and mastitis score were also determined at these times. Infection resulted in a decrease in mean serum Cu, Zn, and Fe concentrations to 89, 83, and 81% of preinfection concentrations at 24 h postchallenge. One-way analysis of variance for repeated measures demonstrated a significant change in serum zinc concentration. The reductions in trace mineral concentrations were of less magnitude than observed following experimental E. coli mastitis.
authors.affiliation: Department of Veterinary Medicine and Surgery, University of Missouri, Columbia 65211, USA. middletonjr@missouri.edu
authors.forename: J R
authors.initials: JR
authors.lastname: Middleton
authors.forename: C D
authors.initials: CD
authors.lastname: Luby
authors.forename: L
authors.initials: L
authors.lastname: Viera
authors.forename: J W
authors.initials: JW
authors.lastname: Tyler
authors.forename: S
authors.initials: S
authors.lastname: Casteel
mesh_terms: D000818:Animals; D002417:Cattle; D002452:Cell Count; D003300:Copper / Q000097:blood*; D005260:Female; D007501:Iron / Q000097:blood*; D007700:Kinetics; D007774:Lactation; D008414:Mastitis, Bovine / Q000097:blood*; D008892:Milk / Q000166:cytology; D013203:Staphylococcal Infections / Q000097:blood / Q000662:veterinary*; D015032:Zinc / Q000097:blood*
chemical_list: D003300:Copper; D007501:Iron; D015032:Zinc