Acromegalic cardiomyopathy: a review of the literature.
Acromegaly is characterized by a high prevalence of cardiovascular complications that account for increased morbidity and mortality. Several studies emphasized the role of GH and IGF-1 excess in cardiac dysfunction. Coexisting factors such as hypertension, glucose tolerance abnormalities and coronary artery disease have a potential role in the progression of the acromegalic cardiomyopathy. Herein, we review the most relevant pathophysiological, functional and morphological findings in this specific disease.
Matta
M P
MP
Department of Endocrinology, CHU Rangueil, Toulouse, France.
Caron
P
P
D000172:Acromegaly / Q000150:complications*; D009202:Cardiomyopathies / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology*; D003327:Coronary Disease / Q000150:complications; D018149:Glucose Intolerance; D019382:Human Growth Hormone / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000150:complications
D019382:Human Growth Hormone