title: Visualizing the immune response to pathogens.
abstract: Advances in immune visualization have enabled the physical tracking of immune responses in vivo. The adaptation of such technology to models of infectious disease holds the promise of a more detailed analysis of host-pathogen interactions in a natural setting. However, the visualization of pathogen-specific immune responses in vivo confronts challenges that are inherent to the study of infectious disease systems. Recent attempts to track pathogen-specific immune responses in vivo validate the usefulness and underline the complexity of this experimental strategy.
authors.affiliation: Department of Medicine, Division of Immunology, University of Connecticut Health Center, Farmington, CT 06030-1319, USA.
authors.forename: Aparna
authors.initials: A
authors.lastname: Srinivasan
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: McSorley
mesh_terms: D000818:Animals; D017951:Antigen Presentation / Q000276:immunology; D000938:Antigen-Presenting Cells / Q000276:immunology*; D003952:Diagnostic Imaging; D000939:Epitopes / Q000276:immunology; D006801:Humans; D018320:Leishmania major / Q000276:immunology*; D016773:Leishmaniasis, Cutaneous / Q000276:immunology* / Q000469:parasitology; D008088:Listeriosis / Q000276:immunology* / Q000382:microbiology; D012480:Salmonella Infections / Q000276:immunology* / Q000382:microbiology; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000939:Epitopes