Amino porphyrins as photoinhibitors of Gram-positive and -negative bacteria.
Twenty four aminoporphyrin derivatives have been tested in vitro for their antibacterial photoactivity against Escherichia coli and Staphylococcus aureus. Two of these compounds, bearing polyamine units, exhibited a significant activity especially against Gram-negative bacteria (E. coli).
Sol
V
V
Université de Limoges, Laboratoire de Chimie des Substances Naturelles, 123, Avenue Albert Thomas, 87060 Limoges, France. vincent.sol@unilim.fr
Branland
P
P
Chaleix
V
V
Granet
R
R
Guilloton
M
M
Lamarche
F
F
Verneuil
B
B
Krausz
P
P
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects* / Q000528:radiation effects*; D008027:Light; D008826:Microbial Sensitivity Tests; D011166:Porphyrins / Q000737:chemistry / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000528:radiation effects*
D000900:Anti-Bacterial Agents; D011166:Porphyrins