Protective effect of Lawsonia alba Lam., against CCl4 induced hepatic damage in albino rats.
The oral administration in varying doses of aqueous suspension of extract of L. alba, bark extract to rats for 10 days afforded good hepatoprotection against CCl4 induced elevation in serum marker enzymes, serum bilirubin, liver lipid peroxidation and reduction in total serum protein, liver glutathione, glutathione peroxidase, glutathione-s-transferase, glycogen, superoxide dismutase and catalase activity. The results suggest hepatoprotective and antioxidant activity of extract of L. alba bark.
Bhandarkar
Manoj
M
Department of Biochemistry, Nagpur University, L.I.T. Premises, Amravati Road, Nagpur 440010, India. manoj_3902@rediffmail.com
Khan
Aqueel
A
D000818:Animals; D002251:Carbon Tetrachloride / Q000037:antagonists & inhibitors / Q000633:toxicity*; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology / Q000503:physiopathology / Q000517:prevention & control*; D031564:Lawsonia Plant / Q000737:chemistry*; D008111:Liver Function Tests; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats
D010936:Plant Extracts; D002251:Carbon Tetrachloride