title: Myocardial injury during standard treatment of an adult with status asthmaticus.
abstract: Asthma affects 5%-10% of adults in the United States. Older adults (> 65 years) with asthma have higher rates of fatal asthma than younger adults. The occurrence of a respiratory emergency, such as status asthmaticus, would seem likely to create a situation of cardiopulmonary dysfunction conducive to myocardial ischemia. However, multiple studies of fatal or near-fatal asthma have failed to incriminate myocardial infarction as a contributing factor. We report a patient without underlying coronary artery disease who sustained myocardial injury consistent with myocardial ischemia and infarction during status asthmaticus while receiving recommended treatment without intravenous sympathomimetics or theophylline.
authors.affiliation: The Quillen Veterans Affairs Medical Center, Mountain Home, Tennessee , USA 37684-4000, USA.
authors.forename: Said B
authors.initials: SB
authors.lastname: Iskandar
authors.forename: Mathew G
authors.initials: MG
authors.lastname: Mathai
authors.forename: Ryland P
authors.initials: RP
authors.lastname: Byrd
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Roy
mesh_terms: D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use*; D003402:Creatine Kinase / Q000096:biosynthesis / Q000097:blood; D052279:Creatine Kinase, MB Form; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007527:Isoenzymes / Q000096:biosynthesis / Q000097:blood; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000209:etiology* / Q000378:metabolism; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency / Q000209:etiology / Q000628:therapy; D013224:Status Asthmaticus / Q000150:complications / Q000188:drug therapy* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000318:Adrenergic beta-Agonists; D018927:Anti-Asthmatic Agents; D005938:Glucocorticoids; D007527:Isoenzymes; D003402:Creatine Kinase; D052279:Creatine Kinase, MB Form