title: Characterization of epoxy resin-based anion-responsive polymers: applicability to chloride sensing in physiological samples.
abstract: The potentiometric properties of an epoxy resin-based anion-responsive polymer and its feasibility as a chloride sensing membrane are described. The response mechanism of the epoxy resin-based membrane is studied by varying the types and contents of epoxy components (e.g., resin, hardener, diluent, and plasticizer). It is found that epoxy resins cured with polyamine-type hardeners have excellent characteristics as chloride-sensing membranes, in terms of their selectivity, stability, sensor lifetime, and adhesion for constructing an all-solid-state sensing device. In addition, effects of the diluent or plasticizer added in an epoxy resin/hardener system on the potentiometric behaviors are investigated. To demonstrate the practical analytical utility of the epoxy resin-based electrodes, chloride levels in various controls and biological specimens (e.g., human sera and whole blood) are determined with a flow-cell system.
authors.affiliation: Department of Chemistry, Kwangwoon University, Seoul 139-701, Korea.
authors.forename: Jae Ho
authors.initials: JH
authors.lastname: Shin
authors.forename: Hyo Lin
authors.initials: HL
authors.lastname: Lee
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Cho
authors.forename: Jeonghan
authors.initials: J
authors.lastname: Ha
authors.forename: Hakhyun
authors.initials: H
authors.lastname: Nam
authors.forename: Geun Sig
authors.initials: GS
authors.lastname: Cha