Use of two sensitive and specific immunoblot markers, em70 and em90, for diagnosis of alveolar echinococcosis.
Antibodies against Echinococcus multilocularis metacestodes were screened by immunoblotting sera from patients with alveolar echinococcosis (n = 39), cystic echinococcosis (n = 109), or other parasitic infections (n = 66) and healthy individuals (n = 32). Two antigens, approximately 70 and 90 kDa, are found to be valuable for confirmatory diagnosis, with a sensitivity and specificity of 100 and 99.51%, respectively.
Korkmaz
Metin
M
Department of Parasitology, School of Medicine, Ege University, Izmir 35100, Turkey. mkorkmaz@med.ege.edu.tr
Inceboz
Tonay
T
Celebi
Fehmi
F
Babaoglu
Aylin
A
Uner
Ahmet
A
D000909:Antibodies, Helminth / Q000097:blood*; D000947:Antigens, Helminth / Q000276:immunology*; D004445:Echinococcosis, Pulmonary / Q000175:diagnosis*; D006801:Humans; D015151:Immunoblotting; D011650:Pulmonary Alveoli; D012680:Sensitivity and Specificity
D000909:Antibodies, Helminth; D000947:Antigens, Helminth