title: [Sildenafil citrate for erectile dysfunction in male kidney transplant recipients].
abstract: OBJECTIVE
  To evaluate the efficacy and safety of sildenafil citrate in man kidney transplant recipients with erectile dysfunction.
  
  
  METHODS
  One hundred and seventy married males, aged 26 approximately 50 years, who had received kidney transplantations at least half a year before and whose serum creatinine was under 133 umol/l, were selected randomly in the study. Their sexual function was investigated according to the International Index of Erectile Function-5 (IIEF-5), and those with erectile dysfunction (ED) were treated with oral sildenafil citrate for 6 months. The efficacy was assessed by IIEF-5.
  
  
  RESULTS
  Fifty-three men with ED received oral sildenafil citrate for 6 months. At the end of the treatment, each index in IIEF-5 increased significantly. There were no interactions between sildenafil and cyclosporine and there was no significant adverse effect of sildenafil on the graft function.
  
  
  CONCLUSIONS
  Sildenafil is an effective and safe agent for the treatment of ED in kidney transplant recipients.
authors.affiliation: Renal Disease Research Center, Department of Urinary Surgery, XinQiao Hospital, Third Military Medical University, Chongqing 400037, China. liufwh@hotmail.com
authors.forename: Feng
authors.initials: F
authors.lastname: Liu
authors.forename: Genfu
authors.initials: G
authors.lastname: Zhang
authors.forename: Xining
authors.initials: X
authors.lastname: Ji
authors.forename: Chibing
authors.initials: C
authors.lastname: Huang
authors.forename: Pingxian
authors.initials: P
authors.lastname: Wang
authors.forename: Mingqi
authors.initials: M
authors.lastname: Fan
mesh_terms: D000328:Adult; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000009:adverse effects / Q000627:therapeutic use*; D011687:Purines; D000068677:Sildenafil Citrate; D013450:Sulfones
chemical_list: D010879:Piperazines; D011687:Purines; D013450:Sulfones; D000068677:Sildenafil Citrate