title: Hair analysis differentiates chronic from acute carbamazepine intoxication.
abstract: This is a report of a 12-year-old epileptic child undergoing chronic treatment with carbamazepine who was found comatose. He was considered to have acute severe drug toxicity. Measurement of carbamazepine concentration in the patient's hair segments together with the carbamazepine blood levels were both important in determining the chronic nature of the patient's intoxication.
authors.affiliation: Department of Pediatrics, University Hospital of Heraklion, Heraklion, Crete, Greece.
authors.forename: Evangelia C
authors.initials: EC
authors.lastname: Mantzouranis
authors.forename: George K
authors.initials: GK
authors.lastname: Bertsias
authors.forename: Eleftherios G
authors.initials: EG
authors.lastname: Pallis
authors.forename: Aristidis M
authors.initials: AM
authors.lastname: Tsatsakis
mesh_terms: D000208:Acute Disease; D000927:Anticonvulsants / Q000097:blood / Q000506:poisoning*; D002220:Carbamazepine / Q000097:blood / Q000506:poisoning*; D002648:Child; D002908:Chronic Disease; D003937:Diagnosis, Differential; D004827:Epilepsy / Q000188:drug therapy*; D005260:Female; D006197:Hair / Q000737:chemistry*; D006801:Humans
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine