title: Tyrosinase-inhibitory furanocoumarin from Angelica dahurica.
abstract: An extract of the roots of Angelica dahurica BENTH. et HOOK. (Umbelliferae) showed potential tyrosinase inhibition against mushroom tyrosinase. Employing a bioassay-linked HPLC method, followed by semipreparative HPLC, the active principle was isolated and characterized as 9-hydroxy-4-methoxypsoralen.
authors.affiliation: College of Pharmacy, Seoul National University, Korea.
authors.forename: Xiang Lan
authors.initials: XL
authors.lastname: Piao
authors.forename: Seung Hoon
authors.initials: SH
authors.lastname: Baek
authors.forename: Man Ki
authors.initials: MK
authors.lastname: Park
authors.forename: Jeong Hill
authors.initials: JH
authors.lastname: Park
mesh_terms: D029969:Angelica; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D011564:Furocoumarins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018517:Plant Roots
chemical_list: D004791:Enzyme Inhibitors; D011564:Furocoumarins; D010936:Plant Extracts; D014442:Monophenol Monooxygenase