title: Transvenous catheter cryoablation of the atrioventricular node and visual assessment of freezing of cardiac tissue using intracardiac echocardiography.
abstract: We investigated the use of a catheter-based cryoablation system on atrioventricular (AV) junction ablation in dogs. In five dogs, the cryoablation catheter was introduced to the AV junction area in order to create transient high degree or complete AV block. Cryo-freezing energy was applied by lowering the temperature to -75 degrees C for five minutes as a single cycle. This cycle was repeated until significant impairment of the AV conduction appeared. Transient high degree and complete AV block was obtained in all five dogs without any adverse effects. The iceball formation was identified by intracardiac echocardiography. Ablation of the AV junction is effective with several freeze-thaw cycles using a transvenous catheter cryoablation system.
authors.affiliation: Cardiovascular Center, Yokohama Red Cross Hospital, Tokyo, Japan.
authors.forename: Kaoru
authors.initials: K
authors.lastname: Okishige
authors.forename: Tomoo
authors.initials: T
authors.lastname: Harada
authors.forename: Mihoko
authors.initials: M
authors.lastname: Kawabata
authors.forename: Kei
authors.initials: K
authors.lastname: Yamashiro
authors.forename: Ryouji
authors.initials: R
authors.lastname: Kishi
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Nakazawa
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Miake
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Isobe
mesh_terms: D000818:Animals; D001283:Atrioventricular Node / Q000601:surgery*; D002404:Catheterization; D003452:Cryosurgery / Q000379:methods*; D004285:Dogs; D004452:Echocardiography; D004562:Electrocardiography; D004566:Electrodes; D005615:Freezing; D006327:Heart Block / Q000000981:diagnostic imaging / Q000209:etiology*