title: Extended pericranial flap and bone graft reconstruction in anterior skull base surgery.
abstract: OBJECTIVE
  The objectives of this study was to establish a rationale for repairing large anterior skull base defects with an extended pericranial flap and split calvarial bone graft; to define large anterior skull base defects as those spanning the anterior cranial measuring at least 3.0 x 4.0 cm; and to describe the surgical technique and compare it with alternative strategies. Study design Thirty-four patients underwent anterior craniofacial resection of anterior skull-based tumors of varying histology with reconstruction using an extended pericranial flap and split calvarial bone graft.
  
  
  RESULTS
  The survival of the pericranial flap and bone graft was maintained in 33 of 34 patients. There was 1 episode of postoperative cerebrospinal fluid leak, 1 episode of osteomyelitis of the bone graft and an epidural abscess, and 1 episode of asymptomatic pneumocephalus.
  
  
  CONCLUSIONS
  Split calvarial bone graft with an extended pericranial flap is an effective technique for reconstructing large anterior skull base defects.
authors.affiliation: University of Maryland School of Medicine, University of Maryland Hospital, Baltimore, MD, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Rodrigues
authors.forename: Bert W
authors.initials: BW
authors.lastname: O'malley
authors.forename: Hinrich
authors.initials: H
authors.lastname: Staecker
authors.forename: Rafael
authors.initials: R
authors.lastname: Tamargo
mesh_terms: D016025:Bone Transplantation / Q000379:methods*; D003399:Craniotomy / Q000009:adverse effects*; D006801:Humans; D019635:Neurosurgical Procedures / Q000379:methods*; D019291:Skull Base / Q000601:surgery; D019292:Skull Base Neoplasms / Q000601:surgery*; D013524:Surgical Flaps; D016896:Treatment Outcome; D014947:Wounds and Injuries / Q000209:etiology / Q000601:surgery*