title: High temporal and spatial resolution 4D MRA using spiral data sampling and sliding window reconstruction.
abstract: Contrast-enhanced magnetic resonance angiography (CE-MRA) requires high spatial resolution to demonstrate detailed vasculature and high temporal resolution to capture the contrast bolus. Sparse bright voxels in MRA permit substantial undersampling in MRI data acquisition, allowing simultaneous high temporal and spatial resolution. We developed a time-resolved 3D MRA technique using the efficient spiral sampling trajectory, and performed off-resonance corrections using inhomogeneity field maps. View sharing and sliding window reconstruction were utilized to generate high temporal resolution. High-resolution 3D angiograms were generated at 1-2 s per frame, with a 5-8 ml gadolinium dose, in patients with vascular disease.
authors.affiliation: Department of Radiology, University of Pittsburg, Pittsburgh, Pennsylvania 15213, USA.
authors.forename: He
authors.initials: H
authors.lastname: Zhu
authors.forename: David G
authors.initials: DG
authors.lastname: Buck
authors.forename: Zhenghui
authors.initials: Z
authors.lastname: Zhang
authors.forename: Honglei
authors.initials: H
authors.lastname: Zhang
authors.forename: Paul
authors.initials: P
authors.lastname: Wang
authors.forename: V Andrew
authors.initials: VA
authors.lastname: Stenger
authors.forename: Martin R
authors.initials: MR
authors.lastname: Prince
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
mesh_terms: D001161:Arteriosclerosis / Q000175:diagnosis*; D003287:Contrast Media; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007866:Leg / Q000098:blood supply*; D018810:Magnetic Resonance Angiography / Q000379:methods*
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA