The treatment of status epilepticus.
Status epilepticus (SE) is a life-threatening emergency that requires prompt treatment, including basic neuroresuscitation principles (the ABCs), antiepileptic drugs to stop the seizure, and identification of etiology. Symptomatic SE is more common in younger children. Treating the precipitating cause may prevent ongoing neurologic injury and facilitates seizure control. A systematic treatment regimen, planned in advance, is needed, including one for refractory status epilepticus (RSE). Here we emphasize definitions, clinical and electroencephalography stages, early treatment, special circumstances that may require immediate seizure control, and treatment of RSE. Because much clinical research in SE has been done in adults, we indicate the patient population studied.
Riviello
James J
JJ
Division of Epilepsy and Clinical Neurophysiology, Critical Care Neurology Service, Department of Neurology, Children's Hospital, Harvard Medical School, Boston, MA, USA.
Holmes
Gregory L
GL
D004569:Electroencephalography; D006801:Humans; D012307:Risk Factors; D013226:Status Epilepticus / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D016896:Treatment Outcome