title: Telithromycin-induced acute interstitial nephritis: a first case report.
abstract: Telithromycin, a ketolide antibiotic used for the treatment of community-acquired respiratory infections, is widely prescribed in primary care practice. Treatment-related adverse events are mainly of gastrointestinal origin and generally mild in intensity. The authors report the first case of telithromycin-induced severe acute interstitial nephritis. Practitioners should be aware of the possibility that telithromycin therapy could result in this form of drug-induced acute renal failure.
authors.affiliation: Department of Nephrology, Clinique et Maternité Sainte Elisabeth, Namur, Belgium. m.tintillier@ibelgique.com
authors.forename: Michel
authors.initials: M
authors.lastname: Tintillier
authors.forename: Lotti
authors.initials: L
authors.lastname: Kirch
authors.forename: Carole
authors.initials: C
authors.lastname: Almpanis
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Cosyns
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Pochet
authors.forename: Charles
authors.initials: C
authors.lastname: Cuvelier
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D006801:Humans; D048628:Ketolides / Q000009:adverse effects* / Q000627:therapeutic use; D007668:Kidney / Q000473:pathology*; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D012141:Respiratory Tract Infections / Q000188:drug therapy
chemical_list: D048628:Ketolides; C106791:telithromycin; D008775:Methylprednisolone