title: 2(S)-Amino-3-[1H-imidazol-4(5)-yl]propyl cyclohexylmethyl ether dihydrochloride and 2(S)-amino-3-[1H-imidazol-4(5)-yl]propyl 4-bromobenzyl ether dihydrochloride.
abstract: (Cyclohexylmethyloxymethyl)(1H-imidazol-4-iomethyl)-(S)-ammonium dichloride, C(13)H(25)N(3)O(+).2Cl(-), and (4-bromobenzyl)(1H-imidazol-4-iomethyl)-(S)-ammonium dichloride, C(13)H(18)BrN(3)O(+).2Cl(-), are model compounds with different biological activities for evaluation of the histamine H3-receptor activation mechanism. Both title compounds occur in almost similar extended conformations.
authors.affiliation: Department of Pharmaceutical Chemistry, University of Kuopio, PO Box 1627, FIN-70211 Kuopio, Finland.
authors.forename: J T
authors.initials: JT
authors.lastname: Kovalainen
authors.forename: E
authors.initials: E
authors.lastname: Wegelius
authors.forename: J A
authors.initials: JA
authors.lastname: Christiaans
authors.forename: J
authors.initials: J
authors.lastname: Huuskonen
authors.forename: J
authors.initials: J
authors.lastname: Gynther