Determination of the structures of four new isomeric cyclitols.
A series of impurities, which were all of the same molecular formula, C17H33NO7, were obtained in the process of voglibose synthesis. After isolation and purification, four isomeric cyclitols were completely assigned by 2D NMR experiments. One of the compounds was established by single-crystal X-ray diffraction analysis as 5,6-dideoxy-5-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino}-1-C-(methoxycyclohexylmethyl)-D-epi-inositol.
Zhang
Hong
H
Department of Chemistry, Zhejiang University, Hang Zhou 310027, PR China.
Sun
Cui-Rong
CR
Ishurd
Omar
O
Pan
Yuan-Jiang
YJ
Ding
Li-Sheng
LS
D002236:Carbohydrate Conformation; D007294:Inositol / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry* / Q000302:isolation & purification; D008958:Models, Molecular; D008970:Molecular Weight; D013237:Stereoisomerism; D014961:X-Ray Diffraction
D007294:Inositol; C102817:voglibose