Intestinal pseudotumorous gouty nodulosis: a colonic tophus without manifestation of gouty arthritis.
A 37-year-old black woman with nephritis secondary to systemic lupus erythematosus, steroid-induced diabetes mellitus, and hypertension presented with fever, nausea, vomiting, and right upper quadrant abdominal pain with distension. Abdominal computed tomography (CT) scan revealed a colonic mass, and CT- guided fine-needle aspiration demonstrated birefringent crystalline material. After several weeks of antibiotic therapy, the patient underwent laparoscopic examination followed by extended right hemicolectomy for a large mass in the subserosa of the transverse colon. Pathological examination of this mass revealed it to be a gouty tophus. To our knowledge, no case of tophaceous gout presenting as an intestinal mass has previously been reported.
Wu
Huiqing
H
Department of Pathology, Mount Sinai School of Medicine, New York, NY, USA.
Klein
Michael J
MJ
Stahl
Rosalyn E
RE
Sanchez
Miguel A
MA
D000328:Adult; D015210:Arthritis, Gouty / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D003082:Colectomy; D003106:Colon / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D003108:Colonic Diseases / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014527:Uric Acid / Q000378:metabolism*
D014527:Uric Acid