Bilateral central retinal vein occlusion associated with multiple myeloma.
OBJECTIVE
To report a case of simultaneous bilateral central retinal vein occlusion (CRVO) associated with multiple myeloma.


METHODS
A 65-year-old woman had sudden, painless loss of vision in both eyes for 20 days. Ophthalmologic examination revealed bilateral CRVO. Appropriate medical workup was conducted, and multiple myeloma was diagnosed as the underlying cause.


RESULTS
Clinical support and chemotherapy effectively controlled paraprotein production, leading to improvement of both systemic and ocular alterations.


CONCLUSIONS
Many conditions have been noted to be associated with CRVO. Based on a Medline search, this is the first report of simultaneous bilateral CRVO as the first manifestation of multiple myeloma, illustrating the need for a primary care ophthalmologist to be involved in the basic assessment for associated underlying diseases in retinal disorders.
Aggio
Fabio B
FB
Department of Ophthalmology, Instituto da Visão - IPEPO, São Paulo, Brazil. aggio@oftalmo.epm.br
Cariello
Angelino J
AJ
Almeida
Manuella S S
MS
Rodrigues
Celso A
CA
De Moraes
Nilva S B
NS
Colleoni
Gisele W B
GW
Farah
Michel E
ME
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D019572:Retinal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D012170:Retinal Vein Occlusion / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D041623:Tomography, Optical Coherence; D014750:Vincristine / Q000627:therapeutic use
D014750:Vincristine; D003907:Dexamethasone; D004317:Doxorubicin