title: Identification of a new HLA-DRB1 allele in three members of an Italian family.
abstract: Abstract A new human leucocyte antigen (HLA)-DRB1 allele, HLA-DRB1*1149, has been identified in three members of an Italian family during routine sequence based typing. This new allele differs from HLA-DRB1*110101 only for a single nucleotide substitution at position 113 of exon 2 resulting in an amino acid change from Valine (GTG) to Alanine (GCG) at codon 38.
authors.affiliation: Transplantation Immunology, San Giovanni Battista Hospital of Turin, Italy. egarino@molinette.piemonte.it
authors.forename: E
authors.initials: E
authors.lastname: Garino
authors.forename: M
authors.initials: M
authors.lastname: Berrino
authors.forename: G
authors.initials: G
authors.lastname: Mazzola
authors.forename: M
authors.initials: M
authors.lastname: Boccadoro
authors.forename: B
authors.initials: B
authors.lastname: Bruno
authors.forename: F
authors.initials: F
authors.lastname: Bertinetto
authors.forename: L
authors.initials: L
authors.lastname: Bertola
authors.forename: P
authors.initials: P
authors.lastname: Caropreso
authors.forename: E
authors.initials: E
authors.lastname: Frisaldi
authors.forename: F
authors.initials: F
authors.lastname: Marin
authors.forename: M L
authors.initials: ML
authors.lastname: Panniello
authors.forename: F
authors.initials: F
authors.lastname: Tondat
authors.forename: A M
authors.initials: AM
authors.lastname: Dall'Omo
mesh_terms: D000483:Alleles; D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D001483:Base Sequence; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D007558:Italy; D008969:Molecular Sequence Data; D016415:Sequence Alignment
chemical_list: D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; C553518:HLA-DRB1*11:01:01 antigen