title: Improved yields for the in situ production of [11C]CH4 using a niobium target chamber.
abstract: The in situ production of [11C]CH4 using a niobium metal target chamber is described. Improved yields are observed in comparison to the previously reported aluminum conical target under similar conditions of beam energy and current. An empirical expression is proposed that quantifies the loss of yield as a function of irradiation time.
authors.affiliation: TRIUMF, Vancouver, BC, Canada V6T 2A3.
authors.forename: Kenneth R
authors.initials: KR
authors.lastname: Buckley
authors.forename: Salma
authors.initials: S
authors.lastname: Jivan
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Ruth
mesh_terms: D000535:Aluminum; D000641:Ammonia / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry; D007553:Isotope Labeling / Q000379:methods*; D008697:Methane / Q000138:chemical synthesis* / Q000737:chemistry*; D009532:Nickel; D009556:Niobium; D009584:Nitrogen / Q000737:chemistry; D019275:Radiopharmaceuticals / Q000138:chemical synthesis*
chemical_list: D019275:Radiopharmaceuticals; D009556:Niobium; D000641:Ammonia; D009532:Nickel; D006859:Hydrogen; D000535:Aluminum; D009584:Nitrogen; D008697:Methane