title: Evaluation of Clonorchis sinensis recombinant 7-kilodalton antigen for serodiagnosis of clonorchiasis.
abstract: The diagnostic applicability of the Clonorchis sinensis recombinant 7-kDa protein was evaluated. In enzyme-linked immunosorbent assays and immunoblots, the protein showed high sensitivities (81.3 and 71.9%, respectively) and specificities (92.6 and 89.7%, respectively) for sera obtained from various helminthic infections. Some paragonimiasis sera showed cross-reactions. The antigen might be valuable in the serodiagnosis of human clonorchiasis.
authors.affiliation: Department of Tropical and Endemic Parasitic Diseases, National Institute of Health, Seoul 122-701, Korea.
authors.forename: Qin-Ping
authors.initials: QP
authors.lastname: Zhao
authors.forename: Sung-Ung
authors.initials: SU
authors.lastname: Moon
authors.forename: Hyeong-Woo
authors.initials: HW
authors.lastname: Lee
authors.forename: Byoung-Kuk
authors.initials: BK
authors.lastname: Na
authors.forename: Seung-Yull
authors.initials: SY
authors.lastname: Cho
authors.forename: Yoon
authors.initials: Y
authors.lastname: Kong
authors.forename: Ming-Sen
authors.initials: MS
authors.lastname: Jiang
authors.forename: Ai-Hua
authors.initials: AH
authors.lastname: Li
authors.forename: Tong-Soo
authors.initials: TS
authors.lastname: Kim
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000276:immunology; D000953:Antigens, Protozoan / Q000276:immunology*; D003003:Clonorchiasis / Q000175:diagnosis* / Q000276:immunology; D003004:Clonorchis sinensis / Q000276:immunology; D003429:Cross Reactions / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D015151:Immunoblotting; D010272:Parasitic Diseases / Q000175:diagnosis / Q000276:immunology; D011994:Recombinant Proteins / Q000276:immunology*; D012680:Sensitivity and Specificity; D012698:Serologic Tests / Q000379:methods
chemical_list: D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan; D011994:Recombinant Proteins