[The diagnosis and surgical treatment for 56 cases with pulmonary and pleural aspergillosis].
OBJECTIVE
To summarize the experience of diagnosis and surgical treatment for pulmonary and pleural aspergillosis.


METHODS
The clinical data of cases with pulmonary and pleural aspergillosis were analyzed retrospectively between September 1972 and June 2003. There were 53 cases with pulmonary aspergillosis and 3 cases with pleural aspergillosis. Aspergillus was found preoperatively in 8 patients by sputum culture (5 cases) or needle biopsy of the lung (2 cases) or fibro-bronchoscopic biopsy (1 case). All patients were treated with surgical procedures following X-ray film or CT scan.


RESULTS
Of 53 cases with pulmonary aspergillosis, 42 lobectomies, 3 segment-Pneumonectomies, and 8 wedge resections were performed. Of three cases with pleural aspergillosis following eliminating their diseased foci in residual pleural space, two underwent thoracoplasty, one underwent postoperative closed chest drainage for one and an half month with fluconazole injected into residual pleural space repeatedly for 1 month (200 mg/100 ml, 1 time per 2 or 3 days). No operative death and major postoperative complications occurred. None of the patients had recurrent symptoms at follow-up.


CONCLUSIONS
We recommend aggressive surgical resection for pulmonary and pleural aspergillosis, and the surgical result is excellent.
Wu
Zhi-yong
ZY
Department of Cardiothoracic Surgery, The First Affiliated Hospital, Medical College of Zhejiang University, Hangzhou 310003, China.
Su
Qun
Q
Zhou
Yu-long
YL
Ni
Yi-ming
YM
Ye
Ding-sheng
DS
D000328:Adult; D000368:Aged; D001228:Aspergillosis / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010998:Pleurisy / Q000175:diagnosis / Q000601:surgery; D011013:Pneumonectomy / Q000379:methods; D012189:Retrospective Studies; D013905:Thoracoplasty; D016896:Treatment Outcome