title: Congenital alacrima in Pierre Robin sequence.
abstract: OBJECTIVE
  To report the presence of congenital alacrima in a patient with Pierre Robin (PR) sequence.
  
  
  METHODS
  A 6-month-old child with diagnosed PR sequence presented to us with dysfunctional lacrimation present since birth. The child subsequently developed bilateral corneal ulcers. This unusual presentation and its management are described in detail, and other ocular associations of the PR sequence are discussed.
  
  
  RESULTS
  Continuous tear supplementation and appropriate treatment with antibiotics controlled the microbial infection. However, the long-term prognosis for visual rehabilitation remained poor in this patient because of the presence of central corneal opacities, persistent dry eye, which would preclude future optical keratoplasty, and possible sensory deprivation amblyopia.
  
  
  CONCLUSIONS
  Alacrima can cause significant ocular morbidity, because persistent ocular surface dryness can be very difficult to manage. Lifelong tear supplementation may be necessary. The association or coexistence of congenital alacrima and the Pierre Robin sequence has not been described before this report.
authors.affiliation: Government Medical College, Sector 32, Chandigarh 160047, India. aryasudesh@yahoo.co.in
authors.forename: Sudesh K
authors.initials: SK
authors.lastname: Arya
authors.forename: Zia
authors.initials: Z
authors.lastname: Chaudhuri
authors.forename: Rajeev
authors.initials: R
authors.lastname: Jain
authors.forename: Rajni
authors.initials: R
authors.lastname: Nahar
authors.forename: Sunandan
authors.initials: S
authors.lastname: Sood
mesh_terms: D015715:Corneal Edema / Q000175:diagnosis / Q000209:etiology; D003320:Corneal Ulcer / Q000175:diagnosis / Q000209:etiology; D005124:Eye Abnormalities / Q000150:complications* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007223:Infant; D007765:Lacrimal Apparatus / Q000002:abnormalities* / Q000000981:diagnostic imaging; D010855:Pierre Robin Syndrome / Q000150:complications* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed