title: Thrombotic thrombocytopenic purpura following cardiovascular surgery: a case report.
abstract: Thrombotic thrombocytopenic purpura, a rare clinical syndrome characterized by thrombocytopenia and microangiopathic hemolytic anemia, was almost uniformly fatal until the introduction of plasma exchange in 1970. The thrombotic thrombocytopenic purpura following cardiovascular surgeries is relatively a new entity with high mortality if untreated. Plasma exchange is the most important therapy in this disease with good clinical outcomes. With the addition of this report, there are now 13 cases of thrombotic thrombocytopenic purpura in association with coronary artery bypass graft reported in the literature.
authors.affiliation: Department of Medicine, West Virginia University School of Medicine, Charleston Division, USA.
authors.forename: Ammar
authors.initials: A
authors.lastname: Almehmi
authors.forename: Amer
authors.initials: A
authors.lastname: Malas
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Jubelirer
mesh_terms: D000368:Aged; D001026:Coronary Artery Bypass; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D011183:Postoperative Complications; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy