title: Crohn's disease; analysis of 105 patients.
abstract: In this paper, 105 patients with Crohn's disease, (47 M, 58 F), mean age 37.4 +/- 42 years were evaluated clinically, demographically and epidemiologically. Mean age of patients at the time of diagnosis was 26.5 +/- 10.9 years. Follow-up period was 2.7 +/- 2.1 years on average. On admission, symptoms or signs were as follows: right lower quadrant pain 90.5%, abdominal mass 18.1%, enterocutaneous fistula 11.4% and subileus 9.5%. Diagnosis of Crohn's disease was established during appendectomy in 14 patients (13.3%). Family history of inflammatory bowel disease was determined only in six patients (5.7%). Intestinal localization were as follows: ileo colonic 52%, ileal 38%, colonic 10%. Clinical forms were inflammatory (68%), fistulous (23%) and obstructive (9%). Sacroiliitis (7.6%), ankylosing spondylitis (4.7%), erythema nodosum (2.9%), pyoderma gangrenosum (1%) were detected as extraintestinal manifestations. Of the patients, 12.4% underwent surgical intervention due to abscess drainage in 6.6%, fistulectomy in 3.8%, stricture resection in 1.9%. Medical therapy alone was sufficient in 75.3% of patients. As a result, our cases mentioned in this paper reflect the general characteristics of Crohn's disease and prominence of regular visits and treatment.
authors.affiliation: Istanbul University, Istanbul Medical Faculty, Department of Gastroenterohepatology, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Ozdil
authors.forename: K
authors.initials: K
authors.lastname: Demir
authors.forename: G
authors.initials: G
authors.lastname: Boztas
authors.forename: A
authors.initials: A
authors.lastname: Danalioglu
authors.forename: C
authors.initials: C
authors.lastname: Karaca
authors.forename: F
authors.initials: F
authors.lastname: Akyüz
authors.forename: N
authors.initials: N
authors.lastname: Aksoy
authors.forename: S
authors.initials: S
authors.lastname: Kaymakoglu
authors.forename: Z
authors.initials: Z
authors.lastname: Mungan
authors.forename: F
authors.initials: F
authors.lastname: Besisik
authors.forename: Y
authors.initials: Y
authors.lastname: Cakaloglu
authors.forename: A
authors.initials: A
authors.lastname: Okten
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000328:Adult; D003424:Crohn Disease / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D006801:Humans; D007077:Ileal Diseases / Q000209:etiology; D007412:Intestinal Fistula / Q000209:etiology; D007415:Intestinal Obstruction / Q000209:etiology; D008297:Male; D014545:Urinary Calculi / Q000209:etiology; D020246:Venous Thrombosis / Q000209:etiology