Bioconversion studies in cultured cells of Corydalis species.
Structural analysis of the metabolites of dopamine and salsolinol in cultured cells of Corydalis species was carried out using the combination of LC-MS and LC-NMR techniques. Metabolic pathways were clarified without the need to isolate the individual metabolites.
Iwasa
K
K
Kobe Pharmaceutical University, Kobe, Japan. K-iwasa@kobepharma-u.ac.jp
Kuribayashi
A
A
Sugiura
M
M
Nishiyama
Y
Y
Ichimaru
M
M
Moriyasu
M
M
Lee
D U
DU
D001711:Biotransformation; D002478:Cells, Cultured; D002851:Chromatography, High Pressure Liquid; D031311:Corydalis / Q000378:metabolism*; D003903:Deuterium; D004298:Dopamine / Q000378:metabolism*; D007546:Isoquinolines / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D012015:Reference Standards; D013056:Spectrophotometry, Ultraviolet
D007546:Isoquinolines; C036617:salsolinol; D003903:Deuterium; D004298:Dopamine