title: Sequential evaluation of left ventricular systolic and diastolic function after radiofrequency catheter ablation.
abstract: Radiofrequency (RF) catheter ablation has become standard therapy for many types of arrhythmias. RF energy may cause deterioration in left ventricular function by damaging the myocardium. The aim of the present study was to assess the changes in left ventricular function after catheter ablation using various echocardiographic parameters. Forty patients (22 women), aged 37 +/- 14 years (range, 15-76 years), underwent catheter ablation for various tachycardias. Routine echocardiogaphic examination was done in all patients. Left ventricular systolic function was evaluated by the modified Simpson method and tissue Doppler. With regard to left ventricular diastolic function parameters, diastolic early (E) and late (A) transmitral filling velocities, deceleration time (DT), isovolumetric relaxation time (IVRT), and tissue Doppler parameters were assessed. All ventricular function parameters were assessed before, and 1 hour, 1 day, and 1 month after the catheter ablation procedure. To avoid any influence of heart rate on diastolic function parameters, the E/A ratio, DT, and IVRT were adjusted to heart rate (cE/A, cDT, cIVRT). No changes in left ventricular systolic function after the ablation were observed. After the ablation procedure (1 hour, 1 day, and 1 month) the cE/A ratio decreased from 1.42 +/- 0.43 to 1.19 +/- 0.40, 1.18 +/- 0.40, and 1.30 +/- 0.33 (P = 0.009), respectively. cDT increased from 210 +/- 54 to 272 +/- 64, 255 +/- 60, 240 +/- 64 (P = 0.001), respectively. Likewise cIVRT increased from 113 +/- 22 to 133 +/- 54, 123 +/- 27, 117 +/- 19 (P = 0.007), respectively. Significant changes were also observed concerning tissue Doppler parameters in assessing diastolic function. Although no significant changes were observed in systolic function after RF ablation, this procedure may have some detrimental effects on ventricular diastolic function para-meters.
authors.affiliation: Cardiology Department, Siyami Ersek Thoracic and Cardiovascular Surgery Center, Instanbul, Turkey.
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Eksik
authors.forename: Sevket
authors.initials: S
authors.lastname: Gorgulu
authors.forename: Mehmet
authors.initials: M
authors.lastname: Eren
authors.forename: Ahmet
authors.initials: A
authors.lastname: Akyol
authors.forename: Izzet
authors.initials: I
authors.lastname: Erdinler
authors.forename: Enis
authors.initials: E
authors.lastname: Oguz
authors.forename: Kadir
authors.initials: K
authors.lastname: Gurkan
authors.forename: Tanju
authors.initials: T
authors.lastname: Ulufer
authors.forename: Tuna
authors.initials: T
authors.lastname: Tezel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D017115:Catheter Ablation; D003971:Diastole; D015150:Echocardiography, Doppler; D022062:Electrophysiologic Techniques, Cardiac; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013599:Systole; D013611:Tachycardia, Atrioventricular Nodal Reentry / Q000503:physiopathology / Q000601:surgery*; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging*; D016277:Ventricular Function, Left / Q000502:physiology*; D014927:Wolff-Parkinson-White Syndrome / Q000503:physiopathology / Q000601:surgery*