Comparative account of certain enzymes in the serum of homo-iothermal vertebrates subjected to production of myocardial infarction by isoproterenol hydrochloride.
Myocardial infarction was produced by subcutaneous administration of isoproterenol hydrochloride (85 mg/kg b.w. for two consecutive days). The myocardial damage was proved by observing increase in the activity of SGOT and SGPT in serum whereas AChE activity was inhibited by increasing Km, without affecting Vmax. The inhibition of AChE and inhibitory kinetic may be useful in the diagnosis and management of salvage of myocardium.
Gaur
Madhavi
M
Department of Biosciences, Barkatullah University, Bhopal-462 026, India.
Kumar
Santosh
S
D000110:Acetylcholinesterase / Q000097:blood*; D000410:Alanine Transaminase / Q000097:blood*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood*; D010856:Columbidae; D004195:Disease Models, Animal; D007545:Isoproterenol; D007700:Kinetics; D009203:Myocardial Infarction / Q000097:blood / Q000139:chemically induced / Q000201:enzymology*; D009206:Myocardium / Q000473:pathology; D051381:Rats
D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000110:Acetylcholinesterase; D007545:Isoproterenol