The first series of chiral 2,2':6',2''-terpyridine tri-N-oxide ligands for Lewis base-catalyzed asymmetric allylation of aldehydes.
The first series of chiral 2,2':6',2''-terpyridine tri-N-oxide ligands have been developed; They were showed to be active Lewis base-catalysts for asymmetric allylation of aldehydes using allyltrichlorosilane with optimal results at 0 degrees C for electron-deficient aromatic aldehydes (yields up to 97% and enantioselectivities up to 86% ee).
Wong
Wing-Leung
WL
Department of Biology and Chemistry and Open Laboratory of Chirotechnology of the Institute of Molecular Technology for drugs Discovery and Synthesis, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon Tong, Hong Kong SAR, China.
Lee
Chi-Sing
CS
Leung
Hon-Kit
HK
Kwong
Hoi-Lun
HL