Concurrent cystic mediastinal lymphangioma and paratesticular rhabdomyosarcoma.
The current report describes a 23-month-old boy with paratesticular rhabdomyosarcoma who was incidentally diagnosed as also having an isolated mediastinal cystic lymphangioma. The association of childhood rhabdomyosarcoma with various congenital anomalies and genetic alterations such as p53 mutations have been well known. However, mediastinal cystic lymphangioma has not been reported among the congenital anomalies diagnosed in rhabdomyosarcoma. Both rhabdomyosarcoma and lymphangioma originate from mesenchymal cells. This association may be coincidental or may point to a common genetic and/or developmental disorder of the mesencymal tissue.
Emir
Suna
S
Department of Pediatric Oncology, Ankara University Faculty of medicine, Cebeci Ankara, Turkey. emirs@ttnet.net.tr
Ugur
Handan
H
Kologlu
Meltem
M
Erekul
Selim
S
Unal
Emel
E
Taçyildiz
Nurdan
N
Yavuz
Gülsan
G
D006801:Humans; D007223:Infant; D018191:Lymphangioma, Cystic / Q000473:pathology; D008297:Male; D008479:Mediastinal Neoplasms / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D012208:Rhabdomyosarcoma / Q000473:pathology; D013736:Testicular Neoplasms / Q000473:pathology