Enhanced affinochromism of polydiacetylene monolayer in response to bacteria by incorporating CdS nano-crystallites.
By incorporating bio-specific receptors, such as p-10,12-pentacosadiyne-1-N-(3,6,9-trioxaundecylamide)-alpha-D-mannopyranoside (MPDA), into 10,12-pentacosadiyonic acid (PDA) monolayer, the MPDA/PDA monolayer underwent affinochromatic transition in response to the bacteria binding to the receptor. Here, we described a new method to study the membrane/macromolececular interaction between Escherichia coli (E. coli) and mannose and its relative affinochromism by modifying MPDA/PDA with CdS nano-crystallites (MPDA/PDA-CdS). CdS not only triggered the strong tropism of the bacteria but also reduced the rigidity of the MPDA/PDA backbone, resulting in the enhanced affinochromism. This discovery might be of significance in basic biophysical studies of membrane/macromolececular and designing novel biosensor.
Zhang
Yuanjian
Y
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Ma
Baoliang
B
Li
Yajun
Y
Li
Jinghong
J
D000114:Acetylene / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000378:metabolism; D001422:Bacterial Adhesion / Q000502:physiology; D015374:Biosensing Techniques / Q000379:methods; D019187:Cadmium Compounds / Q000737:chemistry* / Q000378:metabolism; D003460:Crystallization; D048168:Escherichia coli K12 / Q000737:chemistry* / Q000378:metabolism; D046911:Macromolecular Substances; D008358:Mannose / Q000378:metabolism; D008563:Membrane Lipids / Q000737:chemistry / Q000378:metabolism; D000078789:Polyacetylene Polymer; D011108:Polymers / Q000737:chemistry* / Q000378:metabolism; D053279:Polyynes; D013440:Sulfides / Q000737:chemistry* / Q000378:metabolism; D013499:Surface Properties
D019187:Cadmium Compounds; D046911:Macromolecular Substances; D008563:Membrane Lipids; D000078789:Polyacetylene Polymer; D011108:Polymers; D013440:Sulfides; C034939:cadmium sulfide; D053279:Polyynes; C082361:polydiacetylene; D000114:Acetylene; D008358:Mannose