title: Mesenteric vein thrombosis after surgery and radiotherapy for pancreatic carcinoma. A case report.
abstract: A case is reported of a 54-year-old female patient undergoing the resection of a pancreatic carcinoma with intraoperative radiation therapy (10 Gy) on the tumor bed and subsequent external beam radiotherapy (50 Gy). After surgery the patient presented chronic diarrhea resistant to oral pancreatic enzymes. Twenty-five months postoperatively, mesenteric vein thrombosis was diagnosed after an episode of melena and was treated with conservative therapy. At five-year follow-up the patient had no evidence of neoplastic disease and bowel movements had increased. On imaging examinations, the presence of venous collaterals and cavernous appearance of the portal trunk were documented.
authors.affiliation: Radiation Therapy Department, Università Cattolica del Sacro Cuore, Campobasso, Italy. gmacchia@rm.unicatt.it
authors.forename: Gabriella
authors.initials: G
authors.lastname: Macchia
authors.forename: Alessio G
authors.initials: AG
authors.lastname: Morganti
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Valentini
authors.forename: Lucio
authors.initials: L
authors.lastname: Trodella
authors.forename: M Gabriella
authors.initials: MG
authors.lastname: Brizi
authors.forename: Gregorio
authors.initials: G
authors.lastname: Cina
authors.forename: Sergio
authors.initials: S
authors.lastname: Alfieri
authors.forename: GiovanBattista
authors.initials: G
authors.lastname: Doglietto
authors.forename: Numa
authors.initials: N
authors.lastname: Cellini
mesh_terms: D002277:Carcinoma / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D005260:Female; D006801:Humans; D008551:Melena / Q000209:etiology; D008642:Mesenteric Veins / Q000000981:diagnostic imaging; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D016577:Pancreaticoduodenectomy / Q000009:adverse effects*; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000175:diagnosis / Q000209:etiology*