title: Epidemiological investigation of bloodstream infections by extended spectrum cephalosporin-resistant Escherichia coli in a Taiwanese teaching hospital.
abstract: In an epidemiologic and case-control study including 30 case patients over a 3.5-year period in a Taiwanese university hospital, only beta-lactamase inhibitor use and extended-spectrum cephalosporin use were identified as independent risk factors for nosocomial CMY-2-producing Escherichia coli bloodstream infection, and CMY-2 producers were found more prevalent than extended-spectrum beta-lactamase-producing isolates.
authors.affiliation: Department of Pathology, National Cheng Kung University Hospital, 138 Sheng-Li Rd., Tainan, Taiwan 70428. jingjou@mail.ncku.edu.tw
authors.forename: Jing-Jou
authors.initials: JJ
authors.lastname: Yan
authors.forename: Wen-Chien
authors.initials: WC
authors.lastname: Ko
authors.forename: Jiunn-Jong
authors.initials: JJ
authors.lastname: Wu
authors.forename: Shu-Huei
authors.initials: SH
authors.lastname: Tsai
authors.forename: Chin-Luan
authors.initials: CL
authors.lastname: Chuang
mesh_terms: D000328:Adult; D000368:Aged; D016470:Bacteremia / Q000453:epidemiology / Q000209:etiology*; D016022:Case-Control Studies; D018550:Cephalosporin Resistance; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D008297:Male; D008875:Middle Aged; D019105:Random Amplified Polymorphic DNA Technique; D012307:Risk Factors; D013624:Taiwan / Q000453:epidemiology; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: C103022:beta-lactamase CMY-2; D001618:beta-Lactamases