What do hormones have to do with aging? What does aging have to do with hormones?
It is clear that aging results in alterations of endocrine physiology, which in turn appear to contribute to development of the senescent phenotype. How the underlying basic aging process or processes cause the endocrine cell dysfunctions leading to hormone imbalance is far from clear, but oxidative alteration of cell membranes is an attractive candidate mechanism that might be susceptible to some degree of global remediation.
Harman
S Mitchell
SM
Kronos Longevity Research Institute, Phoenix, AZ 85016, USA. mitch.harman@kronosinstitute.org
D000375:Aging; D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D016922:Cellular Senescence; D004249:DNA Damage; D004032:Diet; D006728:Hormones / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D018384:Oxidative Stress; D010100:Oxygen / Q000378:metabolism
D006728:Hormones; D010100:Oxygen