title: Prediction of inter-segment stability and osteophyte formation on the multi-segment C2-C7 after unilateral and bilateral facetectomy.
abstract: The objective of this study was to determine the intersegment stability, disc degeneration, and osteophytes formation on the multisegment cervical spine (C2-C7) after unilateral and bilateral facetectomy. A geometrically accurate non-linear three-dimensional model of the intact human cervical spine was created from the digitized coordinates of the dry vertebrae. The intact model was validated against the published results under physiological loading conditions. Eight surgically altered models were created from the intact model. The intact and surgical altered models were subjected to physiological loading. The inclusion of five levels in the present model allowed accurate determination of the intersegment responses and internal cortical bone and disc annulus stress in the adjacent spinal components. Results indicated that facetectomy performed on C5-C6 significantly affects the corresponding stress and intersegment motions at the corresponding C5-C6 levels. The maximum increases were 18 per cent for bilateral facetectomy and 7 per cent for unilateral facetectomy under lateral bending. Combined flexion-extension and axial rotation caused an approximately similar amount of increases after total facetectomy. In addition, adjacent segments (C4-C5 and C6-7) also experience a slight increase in the intersegment responses and internal stress after facetectomy. It has been shown that facetectomy of greater than 50 per cent resulted in segment hypermobility and substantial increase in the disc annulus and cortical bone stress. Increase in the stress may lead to osteophytes formation. This study revealed important information that will help clinicians identify the critical intersegment stability and to decide on the amount of facets resection.
authors.affiliation: School of Mechanical and Production Engineering, Nanyang Technological University, Singapore. hongwan@pmail.ntu.egu/sg
authors.forename: Hong-Wan
authors.initials: HW
authors.lastname: Ng
authors.forename: Ee-Chon
authors.initials: EC
authors.lastname: Teo
authors.forename: Qing-Hang
authors.initials: QH
authors.lastname: Zhang
mesh_terms: D002574:Cervical Vertebrae / Q000503:physiopathology* / Q000601:surgery*; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D020342:Finite Element Analysis; D006801:Humans; D007593:Joint Instability / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology* / Q000517:prevention & control; D007796:Laminectomy / Q000009:adverse effects / Q000379:methods*; D008954:Models, Biological; D011379:Prognosis; D016059:Range of Motion, Articular; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013128:Spinal Osteophytosis / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D013314:Stress, Mechanical; D025321:Surgery, Computer-Assisted / Q000379:methods*; D016896:Treatment Outcome