Incidence and risk factors for sexually transmitted infections among women in an Alabama HIV clinic.
The objectives of this study were to assess the prevalence and incidence of curable sexually transmitted infections (STI), i.e., gonorrhea, chlamydial infection, or trichomoniasis, in a cohort of HIV-infected women. The study population was derived from women seeking primary care at an outpatient university HIV clinic who were participants in a women's natural history study. Enrollees (n = 225) were predominantly African-American, heterosexually infected, with mean age 35 years. Mean entry CD4+ T cell count was 405 cells/mm3. Over 6% were STI positive at initial screening. Subsequently, the combined curable STI incidence was 4.82/1000 woman-months over a median of 33 months of observation. Of 36 incident STIs, trichomoniasis was most common (n = 32). Predictors for acquisition of a curable STI included absenteeism at scheduled clinic appointments, RR = 1.99 (1.28, 3.08), and a higher CD4+ T cell count, RR = 1.15 (1.0028, 1.3115) for 100 cells. Interventions to prevent curable STI in HIV-infected women are warranted in primary care settings.
Monteiro
Cheryl-Ann
CA
Department of Medicine, the University of Alabama at Birmingham, Alabama 35294, USA.
Bachmann
Laura H
LH
Desmond
Renee A
RA
Squires
Kathleen E
KE
Vermund
Sten H
SH
Hook
Edward W
EW
Schwebke
Jane R
JR
Hoesley
Craig J
CJ
D000041:Absenteeism; D000328:Adult; D000407:Alabama / Q000453:epidemiology; D018791:CD4 Lymphocyte Count; D002690:Chlamydia Infections / Q000150:complications / Q000453:epidemiology; D005260:Female; D006069:Gonorrhea / Q000150:complications / Q000453:epidemiology; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D015994:Incidence; D015995:Prevalence; D012307:Risk Factors; D012749:Sexually Transmitted Diseases / Q000150:complications / Q000453:epidemiology*; D014245:Trichomonas Infections / Q000150:complications / Q000453:epidemiology