Telithromycin-induced acute interstitial nephritis: a first case report.
Telithromycin, a ketolide antibiotic used for the treatment of community-acquired respiratory infections, is widely prescribed in primary care practice. Treatment-related adverse events are mainly of gastrointestinal origin and generally mild in intensity. The authors report the first case of telithromycin-induced severe acute interstitial nephritis. Practitioners should be aware of the possibility that telithromycin therapy could result in this form of drug-induced acute renal failure.
Tintillier
Michel
M
Department of Nephrology, Clinique et Maternité Sainte Elisabeth, Namur, Belgium. m.tintillier@ibelgique.com
Kirch
Lotti
L
Almpanis
Carole
C
Cosyns
Jean-Pierre
JP
Pochet
Jean-Michel
JM
Cuvelier
Charles
C
D000208:Acute Disease; D000293:Adolescent; D006801:Humans; D048628:Ketolides / Q000009:adverse effects* / Q000627:therapeutic use; D007668:Kidney / Q000473:pathology*; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D012141:Respiratory Tract Infections / Q000188:drug therapy
D048628:Ketolides; C106791:telithromycin; D008775:Methylprednisolone