Sclerosing epithelioid fibrosarcoma with der(10)t(10;17)(p11;q11).
Sclerosing epithelioid fibrosarcoma is a recently described, rare mesenchymal neoplasm. We report a case of sclerosing epithelioid fibrosarcoma that occurred in the lower leg of a 48-year-old man. The karyotype of the tumor exhibited der(1)t(1;10)(p31;p11), der(10)t(10;17)(p11;q11), and der(17) t(11;17)(?;q11). Rearrangement of 10p11 was also found in one previous reported case of this uncommon tumor.
Ogose
Akira
A
Division of Orthopedic Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachi 1-751, Niigata 951-8510, Japan. aogose@med.niigata-u.ac.jp
Kawashima
Hiroyuki
H
Umezu
Hajime
H
Hotta
Tetsuo
T
Gu
Wenguang
W
Yamagiwa
Hiroshi
H
Ito
Tomoyuki
T
Tohyama
Tsuyoshi
T
Nishijima
Hirokazu
H
Endo
Naoto
N
D002869:Chromosome Aberrations; D002879:Chromosomes, Human, Pair 10 / Q000235:genetics*; D002886:Chromosomes, Human, Pair 17 / Q000235:genetics*; D015622:Epithelioid Cells / Q000473:pathology*; D005354:Fibrosarcoma / Q000235:genetics* / Q000473:pathology; D015321:Gene Rearrangement; D006801:Humans; D007621:Karyotyping; D007866:Leg; D008297:Male; D008875:Middle Aged; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012983:Soft Tissue Neoplasms / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic / Q000235:genetics*