Clinical evaluation of a chemiluminescence immunoassay for determination of immunoglobulin g avidity to human cytomegalovirus.
Clinical evaluation of a novel fully automated chemiluminescence immunoassay for determination of immunoglobulin G avidity to human cytomegalovirus (HCMV) showed 92.8% sensitivity and 84.7% specificity in detecting a recent (< or =90 days) primary HCMV infection. The assay appears useful for accurately diagnosing recent primary HCMV infections.
Revello
Maria Grazia
MG
Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Gorini
Giovanna
G
Gerna
Giuseppe
G
D000818:Animals; D000915:Antibody Affinity / Q000276:immunology*; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology*; D008163:Luminescent Measurements / Q000379:methods*; D011247:Pregnancy; D012680:Sensitivity and Specificity
D007074:Immunoglobulin G