Granulocytic sarcoma of the colon and leukemic infiltration of the liver in a patient presenting with hematochezia and jaundice.
Granulocytic sarcoma (GS) is an extramedullary tumor composed of immature cells of the granulocytic series known to occur in patients with myelodysplastic syndrome, chronic myelogenous leukemia, or acute myelogenous leukemia (AML). Involvement of the gastrointestinal tract is relatively rare in GS. We present an extremely rare case of GS of the colon and liver infiltration in a 60-year-old male patient with AML presenting with jaundice and hematochezia and review the literature. It should be kept in mind that hematochezia may be due to colonic involvement of GS besides thrombocytopenia which is usually encountered in patients with AML.
Sevinc
Alper
A
Department of Medical Oncology, Gaziantep University, School of Medicine Sahinbey Medical Center, Gaziantep TR-27310, Turkey. sevinc@gantep.edu.tr
Buyukberber
Suleyman
S
Camci
Celalettin
C
Koruk
Mehmet
M
Savas
M Cemil
MC
Turk
H Mehmet
HM
Sari
Ibrahim
I
Buyukberber
N Mehmet
NM
D003110:Colonic Neoplasms / Q000150:complications* / Q000473:pathology*; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D007565:Jaundice / Q000209:etiology; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000473:pathology*; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D023981:Sarcoma, Myeloid / Q000150:complications* / Q000473:pathology*; D013921:Thrombocytopenia / Q000209:etiology