title: [Incidence of gallbladder stones in renal transplant recipients].
abstract: OBJECTIVE
  Gallbladder stone is one of the major cause of morbidity in adults. Renal transplantation has been found to increase the risk of gallbladder stone formation. The real incidence of gallbladder stones in renal transplant recipients is not exactly known. We performed this study to identify the risk factors for cholecystolithiasis.
  
  
  METHODS
  We compared the prevalence of gallbladder stone in 222 renal transplantation patients with that in 222 age and sex matched controls. Patients who had chronic liver disease, renal disease, and diabetes were excluded from the control group.
  
  
  RESULTS
  In our study, the incidence of gallbladder stones is 8.6% (19/222 patients) in renal transplantation patients, which was significantly higher than 3.60% (8/222 control) in the control group (p=0.029). In the most of our renal transplantation patients, cholecystolithiasis was asymptomatic. We did not find a difference in age, sex, duration after transplantation, causes of renal failure, resistance index between patients with and without gallbladder stones in renal transplantation patients.
  
  
  CONCLUSIONS
  Our results suggest that the incidence of gallbladder stones is higher in renal transplant recipients than non-transplant population in Korea. Further studies will be needed to focus the factors contributing to the gallbladder stone formation after renal transplantation, especially in regard to immunosuppressive drugs.
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Gyeonggi, Korea.
authors.forename: Sung Hyun
authors.initials: SH
authors.lastname: Park
authors.forename: Joon Soo
authors.initials: JS
authors.lastname: Hahm
authors.forename: Sang Seokg
authors.initials: SS
authors.lastname: Seong
authors.forename: Ui Soon
authors.initials: US
authors.lastname: Park
authors.forename: Kyung Hae
authors.initials: KH
authors.lastname: Lee
authors.forename: Yoon Kyung
authors.initials: YK
authors.lastname: Park
authors.forename: Yil Sik
authors.initials: YS
authors.lastname: Hyun
authors.forename: Hang Lak
authors.initials: HL
authors.lastname: Lee
authors.forename: Dong Soo
authors.initials: DS
authors.lastname: Han
authors.forename: Ho Soon
authors.initials: HS
authors.lastname: Choi
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D042882:Gallstones / Q000209:etiology*; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged