title: Effect of human pancreatic juice and bile on the tensile strength of suture materials.
abstract: BACKGROUND
  Several suture materials are used for pancreatojejunal anastomosis. In this study, we tested the durability of these suture materials in human pancreatic juice and bile.
  
  
  METHODS
  Plain and chromic catgut, polyglactin 910, polyglycolic acid, polydioxanone, polypropylene, and silk sutures were incubated in pancreatic juice and bile that was collected from patients. Fifteen samples of each type of suture material were placed in human juices for 1, 3, and 7 days. Tensile strengths were measured with a tensionmeter.
  
  
  RESULTS
  Plain and chromic catgut disintegrated in pancreatic juice and pancreatic juice plus bile mixture. Polyglycolic acid and polyglactin 910 suture materials were vulnerable to pancreatic juice within 7 days. Polydioxanone retained most of its initial strength in pancreatic juice and bile. Polypropylene and silk retained 84% and 92% of their initial strength, respectively.
  
  
  CONCLUSIONS
  We found that polidioxanone was the strongest suture material in pancreatic juice.
authors.affiliation: Fourth General Surgical Department of Haydarpasa Numune Teaching and Training Hospital, Uskudar 34668, Istanbul, Turkey. tmuftuglu@ttnet.net.tr
authors.forename: M A Tolga
authors.initials: MA
authors.lastname: Muftuoglu
authors.forename: Erkan
authors.initials: E
authors.lastname: Ozkan
authors.forename: Abdullah
authors.initials: A
authors.lastname: Saglam
mesh_terms: D000714:Anastomosis, Surgical; D001646:Bile; D001672:Biocompatible Materials; D002398:Catgut; D006801:Humans; D007583:Jejunum / Q000601:surgery*; D008422:Materials Testing; D010179:Pancreas / Q000601:surgery*; D010189:Pancreatic Juice; D016687:Polydioxanone; D011098:Polyglactin 910; D011100:Polyglycolic Acid; D013537:Sutures; D013718:Tensile Strength
chemical_list: D001672:Biocompatible Materials; D011100:Polyglycolic Acid; D016687:Polydioxanone; D011098:Polyglactin 910