title: Cytotoxic chemotherapy administered to two patients with partially refractory leukaemia while receiving intensive care treatment.
abstract: Administration of cytotoxic chemotherapy to a mechanically ventilated patient is a major undertaking. Induction of remission of leukaemia under such circumstances is an extremely rare event. We report two patients with partially refractory acute myeloid leukaemia who achieved remission of their leukaemia after receiving chemotherapy in the intensive care unit. Both patients were subsequently cured by allogeneic bone marrow transplant.
authors.affiliation: Section of Adult Haematology and Bone Marrow Transplant, King Faisal Specialist Hospital and Research Centre, PO Box 3354, 11211 Riyadh, Saudi Arabia. khalid_alanazi@yahoo.com
authors.forename: K A
authors.initials: KA
authors.lastname: Al-Anazi
authors.forename: S
authors.initials: S
authors.lastname: Jacobs
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use*; D016026:Bone Marrow Transplantation; D006801:Humans; D007362:Intensive Care Units; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications / Q000188:drug therapy*; D015473:Leukemia, Promyelocytic, Acute / Q000150:complications / Q000188:drug therapy*; D008297:Male; D012121:Respiration, Artificial