Photodynamic therapy for subungual Bowen's disease.
A 35-year-old police shooting instructor with a 4-year history of Bowen's disease of the nail bed on his right index finger confirmed histologically, was successfully treated with photodynamic therapy (PDT). Four cycles of PDT were used with two different photosensitizers: 20% 5-amino-levulinic acid oil in water emulsion and methyl amino-levulinate (Metvix) cream. The lesion was successfully treated with clinical and histological clearance. There was minimal loss of time from work, with neither functional nor cosmetic deficits.
Tan
Boon
B
Skin and Cancer Foundation Victoria, Victoria, Australia. tboont@vodafone.net.au
Sinclair
Rodney
R
Foley
Peter
P
D000328:Adult; D000622:Aminolevulinic Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D001913:Bowen's Disease / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009262:Nails; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D012878:Skin Neoplasms / Q000188:drug therapy*; D016896:Treatment Outcome
D017319:Photosensitizing Agents; C475457:methyl 5-aminolevulinate; D000622:Aminolevulinic Acid