[The analysis of the factors for postoperative blood pressure recovery of aldosterone producing adenoma patients].
OBJECTIVE
To investigate the factors regarding the recovery of postoperative blood pressure of aldosterone producing adenoma (APA) patients.


METHODS
Sixty-eight patients with APA were recruited and their data including retinal blood vessel by Doppler sonography, urinary trace albumin, pathological changes of renal biopsy and the adrenal tissues around the adenoma were analyzed in order to determine the correlation between these data and postoperative durative hypertension.


RESULTS
Postoperative durative hypertension occurred in 14 cases (41.2%) with increased resistance of unilateral or bilateral central artery of retina, in 16 cases (66.7%) with increased level of urinary trace albumin. Fifteen cases underwent renal biopsy and all of them showed different pathological alterations, 11 cases (73.3%) of which presented with postoperative durative hypertension. The pathological changes of the adrenal tissues around the adenoma is either atrophy or non-atrophy (normal or hyperplasia), 8 cases (40%) and 10 cases (22.2%) of which showed postoperative durative hypertension, respectively.


CONCLUSIONS
The renal pathological changes and increased resistance of retinal blood vessel are the main reasons leading to postoperative hypertension in patients with APA.
Liu
Ding-yi
DY
Department of Urology, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China.
Zhang
Chong-yu
CY
Shao
Yuan
Y
Rui
Wen-bin
WB
Wu
Yu-xuan
YX
Zhou
Yan
Y
Yi
Fang
F
Yang
Jian
J
Wang
Wei-ming
WM
Hao
Cui-lan
CL
Chen
Nan
N
D000293:Adolescent; D000306:Adrenal Cortex Neoplasms / Q000503:physiopathology / Q000601:surgery*; D000311:Adrenal Glands / Q000473:pathology; D018246:Adrenocortical Adenoma / Q000503:physiopathology / Q000601:surgery*; D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D006973:Hypertension / Q000209:etiology; D007668:Kidney / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012161:Retinal Artery / Q000503:physiopathology; D012189:Retrospective Studies; D014655:Vascular Resistance / Q000502:physiology