[Spontaneous muscular haematomas in hemiplegic patients receiving anticoagulation therapy].
BACKGROUND
Muscular hematomas are frequently reported as a complication of anticoagulation therapy.


METHODS
We report six cases of spontaneous muscular hematomas occurring in hemiplegic patients receiving anticoagulation therapy using heparin, low-molecular-weight heparin or fluindione. Anticoagulation therapy was given in prophylactic doses to two patients to prevent deep vein thrombosis and in therapeutic doses to four patients with deep vein thrombosis, pulmonary embolism or cardiac arrhythmia. Two patients experienced episodes of bleeding when heparin and fluindione were temporarily associated.


RESULTS
Contrary to previous reports, the more frequent site of bleeding was not the ilio-psoas muscle (only 2 patients); hematomas were also observed in hip adductors and gluteus muscles. The most striking finding was the constant location of the hematoma on the hemiplegic side.


CONCLUSIONS
Location on the hemiplegic side can lead to underestimating the frequency of neurologic compression by the hematoma; the diagnosis can nevertheless be established by electromyography. Local signs may not be present, but general signs of hypovolemia and anemia are more frequent. Ultrasound may be the first line investigation but in our experience, the results can be misleading and computed tomography (CT) or MRI are often required to confirm the diagnosis.
Galimard
N
N
Service de Médecine Physique et de Réadaptation, Groupe Hospitalier Pitié-Salpêtrière, Paris.
Vassilev
K
K
Chevignard
M
M
Perrigot
M
M
Mazevet
D
D
D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D004576:Electromyography; D005260:Female; D006406:Hematoma / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D006429:Hemiplegia / Q000175:diagnosis / Q000209:etiology*; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000150:complications* / Q000175:diagnosis; D010630:Phenindione / Q000031:analogs & derivatives* / Q000627:therapeutic use; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed
D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight; D010630:Phenindione; C017673:fluindione