title: Adaptation of cardiac myocyte contractile properties to exercise training.
abstract: Recent work suggests that chronic exercise induces alterations in the contractile properties of cardiac myocytes. These alterations include increased sensitivity to activation by Ca, changes in the force-length relationship, and increased power output. A recently observed shift in expression of myosin light chain 1 subunit isoforms induced by training may provide a molecular mechanism for these contractile alterations.
authors.affiliation: Department of Kinesiology, University of Wisconsin, Madison, WI 53706, USA. diffee@education.wisc.edu
authors.forename: Gary M
authors.initials: GM
authors.lastname: Diffee
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D002118:Calcium / Q000378:metabolism / Q000494:pharmacology; D048429:Cell Size / Q000187:drug effects; D006321:Heart / Q000187:drug effects / Q000502:physiology; D008954:Models, Biological; D009200:Myocardial Contraction / Q000187:drug effects; D009206:Myocardium / Q000378:metabolism; D032383:Myocytes, Cardiac / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D010805:Physical Conditioning, Animal / Q000502:physiology*; D051381:Rats
chemical_list: D002118:Calcium