title: Sub-laboratory hypothyroidism and the empirical use of Armour thyroid.
abstract: Evidence is presented that many people have hypothyroidism undetected by conventional laboratory thyroid-function tests, and cases are reported to support the empirical use of Armour thyroid. Clinical evaluation can identify individuals with sub-laboratory hypothyroidism who are likely to benefit from thyroid-replacement therapy. In a significant proportion of cases, treatment with thyroid hormone has resulted in marked improvement in chronic symptoms that had failed to respond to a wide array of conventional and alternative treatments. In some cases, treatment with desiccated thyroid has produced better clinical results than levothyroxine. Research supporting the existence of sub-laboratory hypothyroidism is reviewed, and the author's clinical approach to the diagnosis and treatment of this condition is described.
authors.forename: Alan R
authors.initials: AR
authors.lastname: Gaby
mesh_terms: D000328:Adult; D005260:Female; D020249:Hormone Replacement Therapy; D006801:Humans; D007037:Hypothyroidism / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D013963:Thyroid Hormones / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D013963:Thyroid Hormones