title: Should simultaneous exercise become the standard for adenosine myocardial perfusion imaging?
abstract: Concomitant low-level treadmill exercise with adenosine pharmacologic stress (AdenoEx) during radionuclide myocardial perfusion imaging has become commonly used in recent years, particularly in large-volume laboratories. A number of studies have demonstrated a beneficial impact of AdenoEx protocols. These benefits include decreased side effects, improved safety and patient tolerance, improved target-to-background ratios because of less subdiaphragmatic activity, and improved sensitivity and defect reversibility. In light of these benefits, recent reviews and guidelines call for the addition of low-level exercise to adenosine stress whenever possible.
authors.affiliation: Cardiology Division, Mission Internal Medical Group, Mission Viejo, California 92691, USA. gthomas@mimg.com
authors.forename: Gregory S
authors.initials: GS
authors.lastname: Thomas
authors.forename: Michael I
authors.initials: MI
authors.lastname: Miyamoto
mesh_terms: D000241:Adenosine / Q000009:adverse effects; D005060:Europe; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D017079:Exercise Tolerance / Q000187:drug effects; D006801:Humans; D007089:Image Enhancement; D017202:Myocardial Ischemia / Q000175:diagnosis / Q000503:physiopathology; D015425:Myocardial Reperfusion; D009656:North America; D012680:Sensitivity and Specificity; D014665:Vasodilator Agents / Q000009:adverse effects
chemical_list: D014665:Vasodilator Agents; D000241:Adenosine