Histamine-selective H3 receptor ligands and cognitive functions: an overview.
This review presents a link between histamine and cognition and provides an overview on the effect of histamine and selective ligands of histamine receptors on experimental models for learning, memory and cognitive functions, with a special focus on recently developed H(3) receptor ligands. Studies suggest a tremendous potential for H(3) antagonists in cognitive function disorders.
Vohora
Divya
D
Hamdard University, Department of Pharmacology, Faculty of Pharmacy, New Delhi 110 062, India. divyavohora@hotmail.com
D000818:Animals; D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy / Q000523:psychology; D003071:Cognition / Q000187:drug effects*; D003072:Cognition Disorders / Q000188:drug therapy*; D003866:Depressive Disorder / Q000188:drug therapy / Q000523:psychology; D004827:Epilepsy / Q000188:drug therapy / Q000523:psychology; D017442:Histamine Agonists / Q000627:therapeutic use*; D006633:Histamine Antagonists / Q000627:therapeutic use*; D006801:Humans; D008024:Ligands; D009765:Obesity / Q000188:drug therapy / Q000523:psychology; D018100:Receptors, Histamine H3 / Q000502:physiology*; D012559:Schizophrenia / Q000188:drug therapy; D012893:Sleep Wake Disorders / Q000188:drug therapy / Q000523:psychology
D017442:Histamine Agonists; D006633:Histamine Antagonists; D008024:Ligands; D018100:Receptors, Histamine H3