title: Acetyl-L-carnitine dietary supplementation to old rats increases mitochondrial transcription factor A content in rat hindlimb skeletal muscles.
abstract: Acetyl-L-carnitine (ALCAR) fed to old rats has been reported to partially restore mitochondrial function and ambulatory activity. The results of the effect of ALCAR dietary supplementation to 28-month-old rats on mitochondrial transcription factor A (TFAM) content of rat hindlimb skeletal muscles are reported.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Bari, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Pesce
authors.forename: F
authors.initials: F
authors.lastname: Fracasso
authors.forename: C
authors.initials: C
authors.lastname: Musicco
authors.forename: A M S
authors.initials: AM
authors.lastname: Lezza
authors.forename: P
authors.initials: P
authors.lastname: Cantatore
authors.forename: M N
authors.initials: MN
authors.lastname: Gadaleta
mesh_terms: D000108:Acetylcarnitine / Q000494:pharmacology*; D000818:Animals; D004272:DNA, Mitochondrial / Q000378:metabolism; D019587:Dietary Supplements; D006614:Hindlimb / Q000378:metabolism*; D018482:Muscle, Skeletal / Q000378:metabolism*; D051381:Rats; D015398:Signal Transduction; D013997:Time Factors; D014157:Transcription Factors / Q000096:biosynthesis*
chemical_list: D004272:DNA, Mitochondrial; C489030:Tfam protein, rat; D014157:Transcription Factors; D000108:Acetylcarnitine