Schistosomiasis prophylaxis in vivo using N,N-diethyl-m-toluamide (DEET).
Topical N,N-Diethyl-m-toluamide (DEET) was studied as a schistosomiasis prophylactic in vivo for the use of individuals with limited exposure. Fifteen subjects, on a 3-week expedition to Lake Malawi in September 2001, applied 50% DEET to their skin after exposure to lake water. No subjects developed evidence of a new infection at 3-month follow-up.
Jackson
F
F
Hospital for Tropical Diseases, Mortimer Market Centre, London WC1E 6AU, UK.
Doherty
J F
JF
Behrens
R H
RH
D000279:Administration, Cutaneous; D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D002648:Child; D002675:Child, Preschool; D003671:DEET / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D005618:Fresh Water / Q000469:parasitology; D006801:Humans; D007302:Insect Repellents / Q000009:adverse effects / Q000627:therapeutic use*; D008295:Malawi; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D012553:Schistosomiasis haematobia / Q000517:prevention & control*; D014195:Travel; D016896:Treatment Outcome
D007302:Insect Repellents; D003671:DEET