title: Metastatic Merkel cell tumor to the prostate and bladder.
abstract: Merkel cell carcinoma is an uncommon cutaneous neoplasm of neuroendocrine origin. We report the case of a 71-year-old man with Merkel cell carcinoma metastases to the prostate and bladder presenting with lower urinary tract obstruction. Efforts should be made to optimize the patient's quality of life with the finding of metastatic Merkel cell carcinoma to the bladder or prostate until better adjuvant therapies are identified.
authors.affiliation: Department of Surgery, Division of Urology, University of Western Ontario, London Health Sciences Centre, London, Ontario, Canada.
authors.forename: Douglas P
authors.initials: DP
authors.lastname: Mack
authors.forename: Madeleine
authors.initials: M
authors.lastname: Moussa
authors.forename: Anthony
authors.initials: A
authors.lastname: Cook
authors.forename: Jonathan I
authors.initials: JI
authors.lastname: Izawa
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016190:Carboplatin / Q000008:administration & dosage; D015266:Carcinoma, Merkel Cell / Q000150:complications / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D003131:Combined Modality Therapy; D005047:Etoposide / Q000008:administration & dosage; D005153:Facial Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D017809:Fatal Outcome; D006801:Humans; D007680:Kidney Neoplasms / Q000556:secondary; D008113:Liver Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D010166:Palliative Care; D011471:Prostatic Neoplasms / Q000150:complications / Q000188:drug therapy / Q000556:secondary*; D018714:Radiotherapy, Adjuvant; D013125:Spinal Neoplasms / Q000556:secondary; D020728:Transurethral Resection of Prostate; D014524:Urethral Obstruction / Q000209:etiology; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery
chemical_list: D005047:Etoposide; D016190:Carboplatin