Breast-conserving therapy and sentinel lymph node biopsy are feasible in cancer patients with previous implant breast augmentation.
BACKGROUND
Breast-conserving therapy (BCT) is reported to result in a significant rate of complications and local recurrences in patients with prior implant breast augmentation. The role of sentinel lymph node (SLN) biopsy in these patients is unknown.


METHODS
Retrospective review of patients with prior breast augmentation treated with BCT or SLN biopsy.


RESULTS
Nineteen breast cancers were treated with BCT. Of 17 breasts undergoing adjuvant radiotherapy, 11 (64.7%) retained favorable aesthetic results. Of 9 subpectoral implants, capsular contracture developed in only 1 (11.1%). During follow-up (median 3 years), 1 local recurrence (5.3%) occurred in a patient who refused adjuvant radiotherapy and systemic therapy. Eleven patients underwent SLN biopsy with an identification rate of 100% and a false-negative rate of 0%.


CONCLUSIONS
Breast-conserving therapy inclusive of radiotherapy after implant breast augmentation produced acceptable cosmetic results in nearly two-thirds of patients. Sentinel lymph node mapping in the setting of prior implant augmentation was highly successful and accurate.
Gray
Richard J
RJ
Department of Surgery, Mayo Clinic, 13400 East Shea Blvd., Scottsdale, AZ 85259, USA. gray.richard@mayo.edu
Forstner-Barthell
Adrienne W
AW
Pockaj
Barbara A
BA
Schild
Steven E
SE
Halyard
Michele Y
MY
D000328:Adult; D000368:Aged; D018427:Breast Implants; D001943:Breast Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D005260:Female; D006801:Humans; D015412:Mastectomy, Segmental; D008875:Middle Aged; D011879:Radiotherapy Dosage; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D021701:Sentinel Lymph Node Biopsy