Blood rheological abnormalities in the microcirculation during experimental traumatic shock.
OBJECTIVE
To find whether the principal indices of blood rheological disorders related to the microcirculation undergo drastic changes during the traumatic shock.


METHODS
RBC aggregability and deformability, as well as the systemic hematocrit, were assessed in white laboratory rats with the techniques that provided us with direct and quantitative data.


RESULTS
We found that in the experimental animals the RBC aggregability was sharply increased, the RBC deformability significantly decreased, while the systemic hematocrit underwent considerable lowering during the traumatic shock.


CONCLUSIONS
The blood rheological properties are significantly disordered during development of the traumatic shock.
Tatarishvili
J
J
Microcirculation Research Center, I.Beritashvili Institute of Physiology, Tbilisi, Georgia
Momtselidze
N
N
McHedlishvili
G
G
D000818:Animals; D000925:Anticoagulants / Q000627:therapeutic use; D004195:Disease Models, Animal; D004903:Erythrocyte Aggregation; D004907:Erythrocyte Deformability; D018056:Hemorheology; D008297:Male; D008833:Microcirculation / Q000503:physiopathology*; D051381:Rats; D012774:Shock, Traumatic / Q000097:blood* / Q000188:drug therapy
D000925:Anticoagulants