Antimalarial combinations.
Multidrug resistance has rendered monotherapy for malaria useless in most parts of the world, and has also compromised the usefulness of many of the available combination chemotherapies. New antimalarial regimens are, therefore, urgently needed. We review the various antimalarial combinations that can be used to treat otherwise drug-resistant disease, and discuss what defines an ideal antimalarial combination regimen.
Kremsner
Peter Gottfried
PG
Medical Research Unit, Albert Schweitzer Hospital, Lambaréné, Gabon. peter.kremsner@uni-tuebingen.de
Krishna
Sanjeev
S
D000818:Animals; D000962:Antimalarials / Q000008:administration & dosage*; D018432:Drug Resistance, Multiple; D004359:Drug Therapy, Combination; D006801:Humans; D016778:Malaria, Falciparum / Q000188:drug therapy; D010963:Plasmodium falciparum / Q000187:drug effects
D000962:Antimalarials