title: Lignoren, a new sesquiterpenoid metabolite from Trichoderma lignorum HKI 0257.
abstract: The new compound lignoren (1) was isolated from Trichoderma lignorum HKI 0257 by chromatographic methods. This metabolite has a santalane-like structure, which was elucidated by mass spectrometric and NMR spectroscopic investigations. Lignoren (1) shows a moderate narrow-spectrum of antibacterial and antifungal activity.
authors.affiliation: Hans-Knöll-Institute for Natural Products Research, Beutenbergstr. 11a, D-07745 Jena, Germany. Albrecht.Berg@hki-jena.de
authors.forename: Albrecht
authors.initials: A
authors.lastname: Berg
authors.forename: Hilaire V Kemami
authors.initials: HV
authors.lastname: Wangun
authors.forename: Augusin E
authors.initials: AE
authors.lastname: Nkengfack
authors.forename: Brigitte
authors.initials: B
authors.lastname: Schlegel
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology*; D014242:Trichoderma / Q000254:growth & development / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D012717:Sesquiterpenes; C493325:lignoren