Protein-losing enteropathy associated with systemic lupus erythematosus: response to cyclophosphamide.
Protein-losing enteropathy is a rare manifestation of systemic lupus erythematosus (SLE) leading to hypoalbuminemia and anasarca. We report the case of a woman with SLE who presented chronic hypoalbuminemia diagnosed as protein-losing enteropathy associated with SLE. She was refractory to prednisone and azathioprine administration but showed good response to cyclophosphamide. The diagnosis and management of hypoalbuminemia in lupus-associated enteropathy are discussed.
Werner de Castro
Gláucio R
GR
Rheumatology Unit, Department of Internal Medicine, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil.
Appenzeller
Simone
S
Bértolo
Manoel B
MB
Costallat
Lílian Tereza Lavras
LT
D000328:Adult; D003520:Cyclophosphamide / Q000627:therapeutic use*; D004487:Edema / Q000209:etiology; D005260:Female; D006801:Humans; D034141:Hypoalbuminemia / Q000209:etiology; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy; D011504:Protein-Losing Enteropathies / Q000188:drug therapy* / Q000209:etiology; D012074:Remission Induction
D007166:Immunosuppressive Agents; D003520:Cyclophosphamide