Idiopathic granulomatous vulvitis.
A 20-year-old woman initially presented with clinical evidence of an acute vulval inflammatory disorder incorrectly diagnosed as a Bartholin's abscess. Prolonged healing associated with infection followed attempts to incise and biopsy the area. Over a decade the condition has followed a chronic course with exacerbations and remissions and the vulva has become progressively more swollen and distorted. Lymphangiomas have developed. Histology showed non-necrotizing granulomas. Investigations for Crohn's disease and sarcoidosis were negative. Prednisone resulted in improvement during acute inflammatory episodes.
Rowan
Darion M
DM
National Women's Hospital, Auckland, New Zealand. drowan@ihug.co.nz
Jones
Ronald W
RW
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008556:Melkersson-Rosenthal Syndrome / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D011241:Prednisone / Q000627:therapeutic use; D014847:Vulvitis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*
D000893:Anti-Inflammatory Agents; D011241:Prednisone