Cleaner and convenient preparation of 3-(4,6-dimethoxy-pyrimidin-2-yloxy)-2-methyl-phenol.
Environmental concerns have highlighted the need of cleaner technologies. A cleaner, convenient and selective technology has been developed for the preparation of 3-(4,6-dimethoxy-pyrimidin-2-yloxy)-2-methyl-phenol (DPMP) from 2-methyl-benzene-1,3-diol in water as solvent. The isolated yield of DPMP is up to 86% in good selectivity. The product structure was characterized by conventional methods, 1H-NMR and MS. This technology belongs to the modern concept of environmentally friendly low wastes or non-wastes technology (LWNWT).
Wen
Yue-Zhong
YZ
Institute of Environmental Science, College of Environmental & Resource Sciences, Zhejiang University, Hangzhou 310029, China. wenyuezhong@zjuem.zju.edu.cn
Fang
Zhao-Hua
ZH
Liu
Wei-Ping
WP
D004787:Environmental Pollution / Q000517:prevention & control*; D010636:Phenols / Q000138:chemical synthesis*; D011743:Pyrimidines / Q000138:chemical synthesis*
C498093:3-(4,6-dimethoxy-pyrimidin-2-yloxy)-2-methyl-phenol; D010636:Phenols; D011743:Pyrimidines