title: Strengths and weaknesses of established indirect models to detect recombinant human erythropoietin abuse on blood samples collected 48-hr post administration.
abstract: We studied indirect detection models of erythropoietin abuse (EPO) on blood samples collected 48-hr after administration of the drug during 6 weeks of recombinant human erythropoietin (rHuEPO) treatment. Although the efficiency of OFF-models was preserved, we found a loss of sensitivity of ON-models. This study also revealed an increased percentage of stomatocytes in athletes receiving rHuEPO
authors.forename: Philippe
authors.initials: P
authors.lastname: Connes
authors.forename: Corinne
authors.initials: C
authors.lastname: Caillaud
authors.forename: David
authors.initials: D
authors.lastname: Simar
authors.forename: Sébastien
authors.initials: S
authors.lastname: Villard
authors.forename: Marie-Thérèse
authors.initials: MT
authors.lastname: Sicart
authors.forename: Michel
authors.initials: M
authors.lastname: Audran
mesh_terms: D004300:Doping in Sports; D004921:Erythropoietin / Q000008:administration & dosage / Q000097:blood*; D006801:Humans; D011994:Recombinant Proteins; D012680:Sensitivity and Specificity; D015813:Substance Abuse Detection / Q000379:methods*; D013997:Time Factors
chemical_list: D011994:Recombinant Proteins; D004921:Erythropoietin