2004 Nomenclature for the chicken major histocompatibility (B and Y) complex.
The first standard nomenclature for the chicken (Gallus gallus) major histocompatibility (B) complex published in 1982 describing chicken major histocompatibility complex (MHC) variability is being revised to include subsequent findings. Considerable progress has been made in identifying the genes that define this polymorphic region. Allelic sequences for MHC genes are accumulating at an increasing rate without a standard system of nomenclature in place. The recommendations presented here were derived in workshops held during International Society of Animal Genetics and Avian Immunology Research Group meetings. A nomenclature for B and Y (Rfp-Y) loci and alleles has been developed that can be applied to existing and newly defined haplotypes including recombinants. A list of the current standard B haplotypes is provided with reference stock, allele designations, and GenBank numbers for corresponding MHC class I and class IIbeta sequences. An updated list of proposed names for B recombinant haplotypes is included, as well as a list of over 17 Y haplotypes designated to date.
Miller
Marcia M
MM
Beckman Research Institute, City of Hope National Medical Center, 1450 E. Duarte Road, Duarte, CA 91010, USA. mamiller@coh.org
Bacon
Larry D
LD
Hala
Karel
K
Hunt
Henry D
HD
Ewald
Sandra J
SJ
Kaufman
Jim
J
Zoorob
Rima
R
Briles
W Elwood
WE
D000483:Alleles; D000818:Animals; D002645:Chickens / Q000235:genetics*; D016208:Databases, Factual; D005805:Genes, MHC Class I; D005802:Genes, MHC Class II; D006239:Haplotypes / Q000235:genetics; D008285:Major Histocompatibility Complex / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D011995:Recombination, Genetic; D009626:Terminology as Topic