title: The role of lipoid proteinosis in gingival hypertrophy.
abstract: Hyalinosis cutis et mucosae (lipoid proteinosis, Urbach-Wiethe disease) is a rare syndrome with autosomal recessive inheritance. The disease is characterized by diffuse deposition of a hyalinelike substance in the dermis, submucosal connective tissue, and various internal organs. In this study, the patient demonstrated classic signs and symptoms of lipoid proteinosis except for gingival infiltration. Gingival infiltration is still an unexplainable feature of this disease. In the context of this case, the diagnostic significance of the microscopic findings of the gingival tissues and the possible factors playing a role in gingival hypertrophy, are discussed.
authors.affiliation: Department of Periodontology, Gülhane Military Medical Academy Center of Dental Sciences, Ankara, Turkey. akcaeralp@hotmail.com
authors.forename: Ahmet Eralp
authors.initials: AE
authors.lastname: Akca
authors.forename: Ozlem
authors.initials: O
authors.lastname: Ucok
authors.forename: Ahmet
authors.initials: A
authors.lastname: Akar
authors.forename: Cevat
authors.initials: C
authors.lastname: Can
authors.forename: Kemal
authors.initials: K
authors.lastname: Karakurumer
mesh_terms: D000328:Adult; D005886:Gingival Hypertrophy / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D006818:Hyalin / Q000378:metabolism; D008065:Lipoid Proteinosis of Urbach and Wiethe / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D008297:Male; D013577:Syndrome