Comparison of once daily versus twice daily oral nitrates in stable angina pectoris.
This study aimed to compare patient compliance and treatment effectiveness in patients with stable angina pectoris who were treated with oral nitrates administered once daily versus twice daily. Using electronic measurement, significantly greater adherence to the once daily versus the twice daily nitrate regimen in terms of dosing and timing was found. Better effectiveness of the once daily formulation was also observed.
Kardas
Przemyslaw
P
Department of Family Medicine, Medical University of Lodz, Lodz, Poland. family@csk.am.lodz.pl
D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy*; D006801:Humans; D007548:Isosorbide Dinitrate / Q000008:administration & dosage* / Q000031:analogs & derivatives*; D008875:Middle Aged; D010349:Patient Compliance; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000008:administration & dosage*
D014665:Vasodilator Agents; D007548:Isosorbide Dinitrate; C030397:isosorbide-5-mononitrate