Cryptococcal thyroiditis and hyperthyroidism.
We report a case of cryptococcal thyroiditis presenting with hyperthyroidism that evolved through a transient euthyroid phase to hypothyroidism and finally recovered to normal function. This four-phase clinical presentation is similar to that of subacute thyroiditis, and it is unusual in the setting of infectious nonviral thyroiditis. Cryptococcal thyroiditis is rare; only three cases have been reported. Our patient is the first who survived the disseminated cryptococcal infection with thyroid involvement, thus enabling longitudinal clinical and endocrinologic follow-up.
Avram
Anca M
AM
Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109-0028, USA.
Sturm
Christine A
CA
Michael
Claire W
CW
Sisson
James C
JC
Jaffe
Craig A
CA
D000328:Adult; D003453:Cryptococcosis / Q000382:microbiology / Q000473:pathology; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D005500:Follow-Up Studies; D006801:Humans; D007037:Hypothyroidism / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D011877:Radionuclide Imaging; D013966:Thyroiditis / Q000150:complications* / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000473:pathology