title: Studies on intracellular structures of COS cells by X-ray microscopy.
abstract: COS-7 cells, fixed with glutaraldehyde, were studied using the transmission X-ray microscope at the electron storage ring BESSY, Berlin. The border of the cell, the nucleus, nucleoli and mitochondria of the cells were clearly visualized with the X-ray microscope. In addition, we found many X-ray dense granules preferentially located around the nucleus. Electron microscopy showed that numerous multivesicular bodies, whose structures belong to the endosome-lysosomal system, were present around the nucleus. The size and localization patterns of the X-ray dense granules were quite similar to those of multivesicular bodies. These results strongly suggest that the X-ray dense granules are multivesicular bodies.
authors.affiliation: Department of Physiology, Kansai Medical University, Moriguchi, Osaka 570-8506, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Yamamoto
authors.forename: R
authors.initials: R
authors.lastname: Masaki
authors.forename: P
authors.initials: P
authors.lastname: Guttmann
authors.forename: G
authors.initials: G
authors.lastname: Schmahl
authors.forename: H
authors.initials: H
authors.lastname: Kihara