title: Acute care management of post-TBI spasticity.
abstract: The management of persons with traumatic brain injury (TBI) who have acute spasticity remains a challenge. A correct stratification is essential to clinical care and determination of efficacy from proposed interventions. The secondary severe sequelae of spasticity after TBI can result in profound functional impairment. These concerns are often best addressed early in the patient's course. Limited research in the area of the acute care treatment of severe spasticity is available. The authors employ a review of the available data as well as recount their own clinical experience in the acute care management of severe spasticity to assist in developing an order for the plethora of potential treatments available to clinicians and researchers. We propose to use a case example to emphasize key clinic points in the management of spasticity in the acute care setting.
authors.affiliation: Department of Physical Medicine and Rehabilitation, University of Pittsburgh, 3471 Fifth Avenue, Suite 201 Kaufman Building, Pittsburgh, PA 15213, USA. zafonterd@upmc.edu
authors.forename: Ross
authors.initials: R
authors.lastname: Zafonte
authors.forename: Elie P
authors.initials: EP
authors.lastname: Elovic
authors.forename: Lisa
authors.initials: L
authors.lastname: Lombard
mesh_terms: D000085:Acetates / Q000627:therapeutic use; D000316:Adrenergic alpha-Agonists / Q000627:therapeutic use; D000328:Adult; D000588:Amines; D000927:Anticonvulsants / Q000627:therapeutic use; D001930:Brain Injuries / Q000150:complications*; D002370:Casts, Surgical; D003509:Cyclohexanecarboxylic Acids; D000077206:Gabapentin; D006801:Humans; D008297:Male; D009125:Muscle Relaxants, Central / Q000627:therapeutic use; D009128:Muscle Spasticity / Q000209:etiology* / Q000628:therapy*; D013165:Splints; D005680:gamma-Aminobutyric Acid
chemical_list: D000085:Acetates; D000316:Adrenergic alpha-Agonists; D000588:Amines; D000927:Anticonvulsants; D003509:Cyclohexanecarboxylic Acids; D009125:Muscle Relaxants, Central; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin