title: Meal size and starch content affect gastric emptying in horses.
abstract: BACKGROUND
  Feeding practices have been associated with colic in horses. If meal size and composition have an effect on gastric emptying, this could be one of the mechanisms by which feeding practices are related to the occurrence of colic.
  
  
  OBJECTIVE
  To evaluate the effect of meal size and starch content on solid phase gastric emptying.
  
  
  METHODS
  Solid phase gastric emptying of 3 different radiolabelled meals, small low-starch (SmLS), small high-starch (SmHS) and large high-starch (LgHS) meals, was measured in 5 horses by scintigraphy using 99mTc-disofenin. Data were compared among meals using nonlinear mixed-effects models and paired t tests.
  
  
  RESULTS
  On a percentage basis, SmHS emptied significantly faster than LgHS and SmLS emptied significantly faster than SmHS meals. However, when meals of unequal size were compared by emptying rate in g/min and Kcal/min, LgHS emptied significantly faster than SmHS.
  
  
  CONCLUSIONS
  Meal size and composition affect gastric emptying.
  
  
  CONCLUSIONS
  Further work needs to be performed in order to substantiate the possibility of a relationship between digestive functions and occurrence of colic and gastric ulcers.
authors.affiliation: Nutrition et Santé Digestive Herbivores, ENESAD, Dijon BP 87999, 21079, France.
authors.forename: N
authors.initials: N
authors.lastname: Métayer
authors.forename: M
authors.initials: M
authors.lastname: Lhôte
authors.forename: A
authors.initials: A
authors.lastname: Bahr
authors.forename: N D
authors.initials: ND
authors.lastname: Cohen
authors.forename: I
authors.initials: I
authors.lastname: Kim
authors.forename: A J
authors.initials: AJ
authors.lastname: Roussel
authors.forename: V
authors.initials: V
authors.lastname: Julliand
mesh_terms: D000821:Animal Feed; D000818:Animals; D004435:Eating / Q000502:physiology*; D005746:Gastric Emptying / Q000187:drug effects* / Q000502:physiology; D006736:Horses / Q000502:physiology*; D008297:Male; D011877:Radionuclide Imaging; D011897:Random Allocation; D013213:Starch / Q000008:administration & dosage*; D013270:Stomach / Q000000981:diagnostic imaging; D019785:Technetium Tc 99m Disofenin
chemical_list: D013213:Starch; D019785:Technetium Tc 99m Disofenin