6-[18F]Fluoro-A-85380, a new PET tracer for the nicotinic acetylcholine receptor: studies in the human brain and in vivo demonstration of specific binding in white matter.
Ding
Yu-Shin
YS
Chemistry Department, Brookhaven National Laboratory, Upton, New York 11973, USA.
Fowler
Joanna S
JS
Logan
Jean
J
Wang
Gene-Jack
GJ
Telang
Frank
F
Garza
Victor
V
Biegon
Anat
A
Pareto
Deborah
D
Rooney
William
W
Shea
Colleen
C
Alexoff
David
D
Volkow
Nora D
ND
Vocci
Frank
F
D000328:Adult; D000818:Animals; D001384:Azetidines / Q000378:metabolism* / Q000493:pharmacokinetics; D001921:Brain / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000378:metabolism; D004341:Drug Evaluation; D004353:Drug Evaluation, Preclinical; D005260:Female; D005462:Fluorine Radioisotopes / Q000378:metabolism* / Q000493:pharmacokinetics; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000187:drug effects* / Q000378:metabolism; D010215:Papio; D011237:Predictive Value of Tests; D011849:Radioactive Tracers; D011978:Receptors, Nicotinic / Q000187:drug effects* / Q000378:metabolism; D015203:Reproducibility of Results; D013997:Time Factors; D014055:Tomography, Emission-Computed / Q000379:methods
C492928:6-fluoro-3-(2-azetidinylmethoxy)pyridine; C104288:A 85380; D001384:Azetidines; D005462:Fluorine Radioisotopes; D011849:Radioactive Tracers; D011978:Receptors, Nicotinic