title: Healing of intrabony defects following surgical treatment with or without an Er:YAG laser.
abstract: OBJECTIVE
  The aim of this controlled, parallel design clinical study was to compare the healing of intrabony periodontal defects following treatment with access flap surgery with and without debridement with an Er:YAG laser.
  
  
  METHODS
  Twenty-three patients each of whom exhibited one deep intrabony defect were randomly treated with either access flap surgery followed by root surface and defect debridement using an Er:YAG laser (KEY3) (160 mJ, 10 Hz) (test), or with access flap surgery followed by root surface and defect debridement using hand and ultrasonic instruments (control). The following clinical parameters were recorded at baseline and at 6 months: plaque index; gingival index; bleeding on probing; probing depth (PD); gingival recession; and clinical attachment level (CAL). The primary outcome variable was CAL. No statistically significant differences between the groups were found at baseline.
  
  
  RESULTS
  No serious adverse events were observed after any of the treatments. The results have shown that in the test group the PD decreased from 7.8+/-1.3 to 4.1+/-1.3 mm (p<0.001) and the CAL changed from 9.8+/-2.9 to 7.2+/-2.5 mm (p<0.001). In the control group the PD decreased from 7.8+/-0.8 to 4.6+/-1.6 mm (p<0.001) and the CAL changed from 9.2+/-1.2 to 7.7+/-1.6 mm (p<0.01). The test group displayed a higher tendency for CAL gain, although this tendency did not prove to be statistically significant.
  
  
  CONCLUSIONS
  Within the limits of the present study, it can be concluded that: (i) at 6 months following treatment both therapies led to significant improvements of the investigated clinical parameters, and (ii) an Er:YAG laser may represent a suitable alternative for defect and root surface debridement in conjunction with periodontal surgery.
authors.affiliation: Department of Conservative Dentistry and Periodontology, Johannes Gutenberg-University, Mainz, Germany. anton.sculean@gmx.de
authors.forename: Anton
authors.initials: A
authors.lastname: Sculean
authors.forename: Frank
authors.initials: F
authors.lastname: Schwarz
authors.forename: Mohammad
authors.initials: M
authors.lastname: Berakdar
authors.forename: Péter
authors.initials: P
authors.lastname: Windisch
authors.forename: Nicole B
authors.initials: NB
authors.lastname: Arweiler
authors.forename: Georg E
authors.initials: GE
authors.lastname: Romanos
mesh_terms: D016301:Alveolar Bone Loss / Q000503:physiopathology*; D002908:Chronic Disease; D003646:Debridement; D003746:Dental Enamel Proteins / Q000627:therapeutic use; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D010518:Periodontitis / Q000601:surgery* / Q000628:therapy; D010865:Pilot Projects; D011446:Prospective Studies; D016745:Root Planing; D016896:Treatment Outcome; D014945:Wound Healing / Q000528:radiation effects
chemical_list: D003746:Dental Enamel Proteins; C109069:enamel matrix proteins