Histopathology of cutaneous amebiasis.
Cutaneous amebiasis (CA) is the manifestation in the skin and underlying soft tissues of the pathogenic properties of Entamoeba histolytica, which may be the only expression of the infection or may be associated with disease in other organs. So far, there have been only isolated case reports on this disease. We herein report the histopathologic findings on a series of seven cases, six adults and one child, of CA. The most common findings include ulcers, areas of necrosis, mixed inflammatory infiltrates, and the presence of trophozoites, the invasive form of the parasite. CA is a very rare and severe disease, it is progressive and destructive; erythrophagocytosis, a microscopic sign of pathogenicity, is always seen in CA.
Magaña
Mario
M
Hospital General de México/Universidad Nacional Autónoma de México, Mexico City, Mexico. dermatopatologia@att.net.mx
Magaña
Mario L
ML
Alcántara
Avissai
A
Pérez-Martín
Miguel A
MA
D000328:Adult; D000562:Amebiasis / Q000188:drug therapy / Q000469:parasitology / Q000473:pathology*; D000818:Animals; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000977:Antiparasitic Agents; D004640:Emetine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004748:Entamoeba histolytica / Q000254:growth & development / Q000276:immunology / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D012876:Skin Diseases, Parasitic / Q000469:parasitology / Q000473:pathology*; D016896:Treatment Outcome; D014456:Ulcer / Q000469:parasitology / Q000473:pathology
D000890:Anti-Infective Agents; D000977:Antiparasitic Agents; D008795:Metronidazole; C086742:dehydroemetine; D004640:Emetine