title: Effects of cantharidinimides on human carcinoma cells.
abstract: Modification of the cantharidinimide structure led to the discovery of a novel class of antitumor compounds. These cantharidinimide derivatives containing aliphartic, aryl, and pyridyl groups showed some effect in vitro against HepG2 and HL-60 cells.
authors.affiliation: Department of Medicinal Chemistry, Taipei Medical University School of Pharmacy, Taiwan.
authors.forename: Lun-Huei
authors.initials: LH
authors.lastname: Lin
authors.forename: Hsu-Shan
authors.initials: HS
authors.lastname: Huang
authors.forename: Chiung-Chang
authors.initials: CC
authors.lastname: Lin
authors.forename: Lin-Wen
authors.initials: LW
authors.lastname: Lee
authors.forename: Pen-Yuan
authors.initials: PY
authors.lastname: Lin
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology*; D002193:Cantharidin / Q000737:chemistry / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects / Q000502:physiology; D001517:Coleoptera; D006801:Humans; D007094:Imides / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000970:Antineoplastic Agents; D007094:Imides; D002193:Cantharidin