[The association of lung cancer with asbestos and tobacco smoking].
This work summarises the potential association link for lung cancer between asbestos and smoking. This link emerges not only from different epidemiological and experimental studies, but also from a wide data collection carried out by an omogeneous Italian industrial group. The examination of the data set has led to the conclusion that the simultaneous exposition to asbestos and tobacco's smoke entails a factor, usually multiplicative and also partially additive, in relation to lung cancer; on the other hand, it does not seem to have a great relevance for mesothelioma pleurico. On the basis of this evidence, the Authors focus in particular on the measures of prevention in the contest of work conditions, in order to highlight the impact of the two carcinogenic agents in workers.
Savastano
L
L
Dipartimento di Scienze di Sanità Pubblica G. Sanarelli, Fac. di Medicina e Chirurgia, Università degli Studi di Roma La Sapienza, Roma, Italia.
Bonacci
S
S
Saracino
V
V
Longo
M
M
D000395:Air Pollutants, Occupational / Q000009:adverse effects; D001194:Asbestos / Q000009:adverse effects*; D002273:Carcinogens / Q000009:adverse effects*; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000209:etiology*; D008654:Mesothelioma / Q000453:epidemiology / Q000209:etiology; D009784:Occupational Diseases / Q000453:epidemiology / Q000209:etiology; D016273:Occupational Exposure / Q000009:adverse effects*; D010997:Pleural Neoplasms / Q000453:epidemiology / Q000209:etiology; D012907:Smoking / Q000009:adverse effects*; D013997:Time Factors
D000395:Air Pollutants, Occupational; D002273:Carcinogens; D001194:Asbestos