Heck-Suzuki-Miyaura domino reactions involving ynamides. An efficient access to 3-(arylmethylene)isoindolinones.
[reaction: see text] Substituted 3-(arylmethylene)isoindolin-1-ones can be efficiently synthesized in a stereoselective manner from various ynamides and boronic acids by palladium-catalyzed Heck-Suzuki-Miyaura domino reactions.
Couty
Sylvain
S
Laboratoire de Chimie Organique, associé au CNRS, ESPCI, 10 rue Vauquelin, 75231 Paris Cedex 05, France.
Liégault
Benoît
B
Meyer
Christophe
C
Cossy
Janine
J