Non-specific febrile illness by Coxsackievirus A16 in a 6-day-old newborn.
A case of non-specific febrile illness by Coxsackievirus A 16 (CA 16) in a 6-day-old newborn whose mother had developed hand, foot and mouth disease manifestations 2 days after delivery is reported. Notwithstanding the concurrence of negative circumstances like the presence of the enterovirus genome in the cerebrospinal fluid, absence of type specific neutralizing antibody and a few days of life, the newborn recovered 3 days after the onset of fever. This case, also characterized by the absence of mucosal and cutaneous erythematous manifestations typical of CA16 infection, draws attention to the possibility that non-specific febrile illness in newborns usually suspected of bacterial origin may have an enteroviral cause.
Portolani
M
M
Department of Laboratory Medicine, University Hospital of Modena and Reggio Emilia, Modena, Italy. portolani.m@policlinico.mo.it
Bartoletti
A M
AM
Pietrosemoli
P
P
Beretti
F
F
Della Casa Muttini
E
E
Roversi
M F
MF
Livio
L
L
Ferrari
F
F
D003384:Coxsackievirus Infections / Q000150:complications / Q000175:diagnosis*; D005334:Fever / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D008297:Male