title: High dose intravenous methylprednisolone in the treatment of severe acute respiratory syndrome.
abstract: The case of a 72-year-old woman with probable severe acute respiratory syndrome is reported. While on treatment with ribavirin and antibiotics (for community-acquired pneumonia), the patient continued to have progressive clinical deterioration and chest radiographic evidence of respiratory deterioration. Pulse dose intravenous corticosteroids were used in an unsuccessful attempt to treat the inflammatory component of this respiratory illness.
authors.affiliation: Department of Medicine, University of Toronto, Ontario, Canada.
authors.forename: Sharmistha
authors.initials: S
authors.lastname: Mishra
authors.forename: Winnie M
authors.initials: WM
authors.lastname: Lee
authors.forename: Brian
authors.initials: B
authors.lastname: Bressler
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Juvet
authors.forename: Denis
authors.initials: D
authors.lastname: Hadjiliadis
mesh_terms: D000368:Aged; D017809:Fatal Outcome; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D007262:Infusions, Intravenous; D008775:Methylprednisolone / Q000008:administration & dosage*; D020551:Pulse Therapy, Drug; D011859:Radiography; D045169:Severe Acute Respiratory Syndrome / Q000000981:diagnostic imaging / Q000188:drug therapy*
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone