[Advances in research on the target antigens of antisperm antibodies].
Antisperm antibodies can lead to immunological infertility. Further research on the target antigens of antisperm antibodies may help to discover the causal relationship of antisperm antibodies to infertility. This paper summarizes the structure and function of the six target antigens of antisperm antibodies found recently, so as to discover the causal relationship of the antibodies to infertility and provide a basis for screening a vaccine for immunological contraception.
Chen
Deyu
D
Laboratory of Reproduction & Genetics, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.
Huang
Yufeng
Y
D016564:Amyloid beta-Protein Precursor / Q000737:chemistry / Q000276:immunology; D000906:Antibodies / Q000276:immunology*; D000937:Antigen-Antibody Reactions; D003598:Cytoskeletal Proteins; D006023:Glycoproteins / Q000737:chemistry / Q000276:immunology; D006801:Humans; D007248:Infertility, Male / Q000209:etiology; D008297:Male; D009419:Nerve Tissue Proteins / Q000737:chemistry / Q000276:immunology; D028861:Nuclear Pore Complex Proteins; D009687:Nuclear Proteins; D013094:Spermatozoa / Q000276:immunology*; D060589:Zyxin
C084104:APLP2 protein, human; D016564:Amyloid beta-Protein Precursor; D000906:Antibodies; D003598:Cytoskeletal Proteins; D006023:Glycoproteins; D009419:Nerve Tissue Proteins; D028861:Nuclear Pore Complex Proteins; D009687:Nuclear Proteins; C119930:RGPD8 protein, human; C092842:ZYX protein, human; D060589:Zyxin