title: Endodermal sinus tumor of the parotid gland in a child.
abstract: We report a case of a 16-month-old girl with a primary endodermal sinus tumor (EST) of the parotid gland. The girl was admitted to the hospital with a left side cervical tumor with a quick growth (within 3 wk). The tumor was surgically resected. The gross examination showed a 7.0-cm hemorrhagic and fragmentized mass. Diagnosis of an EST was established on the hematoxylin and eosin-stained slides from the resected material. Elevated serum alpha-fetoprotein (AFP) levels were detected and follow-up examinations of the patient did not show ESTs in other locations or other manifestations due to the tumor. The patient received chemotherapy after the surgery and remained alive without evidence of disease at the time of this writing (2 years after the diagnosis). As far as we know, this is the second report in the literature of a parotid gland's EST.
authors.affiliation: Department of Pathology, Hospital do Cancer, Rua Professor Antonio Prudente 211, São Paulo 01 509-900, Brazil. ssredni@ludwig.org.br
authors.forename: Simone Treiger
authors.initials: ST
authors.lastname: Sredni
authors.forename: Isabela Werneck
authors.initials: IW
authors.lastname: da Cunha
authors.forename: Nevigolino Pereira
authors.initials: NP
authors.lastname: de Carvalho Filho
authors.forename: Jose
authors.initials: J
authors.lastname: Magrin
authors.forename: Clovis Antonio Lopes
authors.initials: CA
authors.lastname: Pinto
authors.forename: Luis Fernando
authors.initials: LF
authors.lastname: Lopes
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D018240:Endodermal Sinus Tumor / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant; D010307:Parotid Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D011184:Postoperative Period; D000509:alpha-Fetoproteins / Q000378:metabolism
chemical_list: D000509:alpha-Fetoproteins