title: Drug use--problem in pregnancy.
abstract: OBJECTIVE
  The consumption of drugs during pregnancy considered as a specific medical problem. Drug consumption and drug compliance in pregnancy were analysed in our study.
  
  
  METHODS
  Structured questionnaire and data from mothers were used as principal sources for analysis. Consumption of drugs and compliance with therapy were evaluated in 331 pregnant women, 60% city and 40% rural population, of Region Nitra, Slovakia, after their child birth.
  
  
  RESULTS
  Drug's use was confirmed in 75% of pregnant women. The consumption was significantly higher in the first and second pregnancy when compared to the females by in their third or further pregnancies. Medical prescription was the reason of drug use in 89% pregnant women. The number of prescribed drugs similarly as the total consumption was higher in the first and second pregnancies. We noted medical prescribing drug compliance in 70% pregnant women. 16% of pregnant women used anagetic drugs, out of whom 57% on the basis of medical prescription.
  
  
  CONCLUSIONS
  Adverse drug reactions (gastrointestinal problems and)headache were reported by 15% of pregnant women. In the observed group 6% of women gave birth premature infants (once gemini, once trimini). Two newborns overcomed sepsis. One baby suffered from cheilognatopalatoschisis and two newborns from vitium cordis congenitum. We do not suppose any correlation between child abnormalities and drug consumption during pregnacy. (Tab. 1, Ref. 9.).
authors.affiliation: Department of Neonatology, Teaching Hospital, Nitra, Slovakia. adurisova@fnnitra.sk
authors.forename: A
authors.initials: A
authors.lastname: Durisova
authors.forename: L
authors.initials: L
authors.lastname: Magulova
mesh_terms: D004363:Drug Utilization / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D011247:Pregnancy