title: Release of silica, calcium, phosphorus, and fluoride from glass ionomer cement containing bioactive glass.
abstract: The aim of this study was to examine the release of silica (Si), calcium (Ca), phosphorous (P), and fluoride (F) from conventional glass ionomer cement (GI) and resin-modified glass ionomer cement (LCGI), containing different quantities of bioactive glass (BAG). Further aim was to evaluate in vitro biomineralization of dentine. The release of Si increased with the increasing immersion time from the specimens containing BAG, whereas the amount of Ca and P decreased indicating in vitro bioactivity of the materials. LCGI with 30wt% of BAG showed highest bioactivity. It also showed CaP-like precipitation on both the surface of the test specimens and on the dentin discs immersed with the material. Within the limitations of this study, it can be concluded that a dental restorative material consisting of glass ionomer cements and BAG is bioactive and initiates biomineralization on dentin surface in vitro.
authors.affiliation: Department of Prosthetic Dentistry and Biomaterials Research, Institute of Dentistry, University of Turku, Lemminkäisenkatu 2, 20520, Finland. helena.yli-urpo@utu.fi
authors.forename: Helena
authors.initials: H
authors.lastname: Yli-Urpo
authors.forename: Pekka K
authors.initials: PK
authors.lastname: Vallittu
authors.forename: Timo O
authors.initials: TO
authors.lastname: Närhi
authors.forename: Ari-Pekka
authors.initials: AP
authors.lastname: Forsback
authors.forename: Marju
authors.initials: M
authors.lastname: Väkiparta
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D002118:Calcium / Q000737:chemistry*; D003804:Dentin / Q000737:chemistry / Q000648:ultrastructure; D005459:Fluorides / Q000737:chemistry*; D005898:Glass / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D010758:Phosphorus / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D010758:Phosphorus; D012822:Silicon Dioxide; D005459:Fluorides; D002118:Calcium