title: [Biomechanical study of medical hard tissue adhesive bonding butterfly fracture fragment in middle part of fresh human tibia].
abstract: A medical hard tissue adhesive, octyl-a-cyanoacrylate, was tested in 6 fresh human tibiae. A 90 degrees butter-fly fracture fragment was made in the middle part of tibia by bandsaw. The compressive stress, torsional stress and angular deflection were assessed before and after osteoectomy respectively. After adhesive bonding, the compressive stress, torsional stress and angular deflection were tested again. The butterfly fracture fagment decreased the bending strength, torsion strength, yielding strength of tibia bone. In torsion test, the torque of tibia before osteoectomy is greater than bonded tibia, the bonded tibia is greater than that of the unbonded tibia. In compression test, before adhesive bonding broken, the compressive curve slope of tibia before osteoectomy is greater than that of bonded tibia, the bonded tibia is greater than that of the unbonded tibia. In angular deflection test before adhesive bonding of broken,the curve slope of tibia before osteoectomy is not different from that of bonded tibia (P>0.05), the slope the bonded tibia is greater than the slope of unbonded tibia(P<0.05). The elastic modulus, rigidity coefficient and moment of area inertia show no statistical difference between the bonded tibia and intact tibia. The used of medical hard tissue adhesive to bond the fracture fragment could improve the bending strength, torsion strength, yielding strength of tibia bone. In operation, it can reduce the soft tissue injury when the fracture fragment is being fixed, and this will benefit bone healing.
authors.affiliation: Orthopeadic Department of West China Hospital, Sichuan University, Chengdu 610041, China
authors.forename: Bo
authors.initials: B
authors.lastname: Lu
authors.forename: Zhongqi
authors.initials: Z
authors.lastname: Tu
authors.forename: Fuxing
authors.initials: F
authors.lastname: Pei
authors.forename: Mengshi
authors.initials: M
authors.lastname: Chen
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
mesh_terms: D001696:Biomechanical Phenomena; D001843:Bone Cements / Q000627:therapeutic use*; D003487:Cyanoacrylates / Q000737:chemistry / Q000627:therapeutic use*; D005593:Fracture Fixation, Internal / Q000379:methods; D017102:Fracture Healing; D018460:Fractures, Comminuted / Q000601:surgery; D006801:Humans; D008422:Materials Testing; D013718:Tensile Strength; D013977:Tibia / Q000601:surgery; D013978:Tibial Fractures / Q000601:surgery*; D014014:Tissue Adhesives / Q000737:chemistry / Q000627:therapeutic use*
chemical_list: D001843:Bone Cements; D003487:Cyanoacrylates; D014014:Tissue Adhesives; C100832:octyl 2-cyanoacrylate