Helicobacter pylori infection in patients with autoimmune thrombocytopenic purpura.
OBJECTIVE
To compare the prevalence of Helicobacter pylori (H pylori) infection in autoimmune thrombocytopenic purpura (AITP) patients with that of nonthrombocytopenic controls, and to evaluate the efficacy of the treatment in H pylori(+) and H pylori(-) AITP patients.


METHODS
The prevalence of gastric H pylori infection in 38 adult AITP patients (29 female and 9 male; median age 27 years; range 18-39 years) who consecutively admitted to our clinic was investigated.


RESULTS
H pylori infection was found in 26 of 38 AITP patients (68.5%). H pylori infection was found in 15 of 23 control subjects (65.2%). The difference in H pylori infection between the 2 groups was not significant. Thrombocyte count of H pylori-positive AITP patients was significantly lower than that of H pylori-negative AITP patients (P<0.05). Thrombocyte recovery of H pylori-positive group was less than that of H pylori-negative group (P<0.05).


CONCLUSIONS
H pylori infection should be considered in the treatment of AITP patients with H pylori infection.
Kurtoglu
Erdal
E
Feritpasa Mahallesi, Umit Bahadir Turk Sokak, No: 21/4 Girgic Apt, Konya 42060, Turkey. erdalkurtoglu@yahoo.com
Kayacetin
Ertugrul
E
Ugur
Aysegul
A
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D016481:Helicobacter Infections / Q000150:complications* / Q000453:epidemiology*; D016480:Helicobacter pylori; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008297:Male; D010976:Platelet Count; D015995:Prevalence; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000150:complications* / Q000188:drug therapy*; D013256:Steroids / Q000627:therapeutic use*; D016896:Treatment Outcome
D016756:Immunoglobulins, Intravenous; D013256:Steroids