title: Generalized spike-wave discharges with focal onset in a patient with head trauma and diffuse cerebral lesions: a case report with EEG and cranial MRI findings.
abstract: The role of cerebral lesions associated with absence seizures, outside the frontal lobe, has not been demonstrated by both electroencephalography and neuroimaging techniques until now, to our knowledge. We present a case with absence seizures and EEGs with generalized 3 Hz spike-wave patterns that were preceded by a burst of spike-waves on the right parieto-occipital region. The patient had a history of head trauma, and cranial MRI revealed lesions that might be responsible for the seizures. The patient's lateralized and localized EEG findings were probably a representation of secondary bilateral synchrony (SBS). The mechanism of SBS is considerably more complex than a simple triggering of generalized spike-wave complexes from a single cortical focus.
authors.affiliation: Department of Neurology, Hacettepe University School of Medicine, Ankara, Turkey.
authors.forename: F Irsel
authors.initials: FI
authors.lastname: Tezer
authors.forename: Nese
authors.initials: N
authors.lastname: Dericioglu
authors.forename: Serap
authors.initials: S
authors.lastname: Saygi
mesh_terms: D000293:Adolescent; D006259:Craniocerebral Trauma / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D004569:Electroencephalography; D004832:Epilepsy, Absence / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009778:Occipital Lobe; D010296:Parietal Lobe / Q000503:physiopathology