Tyrosinase-inhibitory furanocoumarin from Angelica dahurica.
An extract of the roots of Angelica dahurica BENTH. et HOOK. (Umbelliferae) showed potential tyrosinase inhibition against mushroom tyrosinase. Employing a bioassay-linked HPLC method, followed by semipreparative HPLC, the active principle was isolated and characterized as 9-hydroxy-4-methoxypsoralen.
Piao
Xiang Lan
XL
College of Pharmacy, Seoul National University, Korea.
Baek
Seung Hoon
SH
Park
Man Ki
MK
Park
Jeong Hill
JH
D029969:Angelica; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D011564:Furocoumarins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018517:Plant Roots
D004791:Enzyme Inhibitors; D011564:Furocoumarins; D010936:Plant Extracts; D014442:Monophenol Monooxygenase