Three-dimensional anisotropy contrast imaging of gliomatosis cerebri: two case reports.
BACKGROUND
Magnetic resonance imaging (MRI) can provide a preoperative diagnosis of gliomatosis cerebri, but the findings sometimes do not correspond with the clinical symptoms or histologic findings.


METHODS
Three-dimensional anisotropy contrast (3DAC) imaging was used to assess damage to the neuronal fibers in two patients with gliomatosis cerebri who presented with only mental deterioration. Conventional MRI depicted markedly abnormal findings consisting of widespread areas of abnormally high signal intensity in the corpus callosum and in the bilateral white matter in both cases. In contrast, 3-D AC imaging showed no abnormality except for small dark areas in the corpus callosum or white matter.


CONCLUSIONS
3-D AC imaging provides more accurate information about damage to the neuronal fibers in cases of gliomatosis cerebri than other MRI techniques.
Inoue
Takashi
T
Department of Neurosurgery, Iwate Medical University School of Medicine, 19-1 Uchimaru, Morioka, Iwate 020-8505, Japan.
Ogasawara
Kuniaki
K
Beppu
Takaaki
T
Ogawa
Akira
A
D000368:Aged; D016880:Anisotropy; D003287:Contrast Media; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000592:standards; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018302:Neoplasms, Neuroepithelial / Q000175:diagnosis*; D009412:Nerve Fibers / Q000473:pathology
D003287:Contrast Media