title: 6-[18F]Fluoro-A-85380, a new PET tracer for the nicotinic acetylcholine receptor: studies in the human brain and in vivo demonstration of specific binding in white matter.
authors.affiliation: Chemistry Department, Brookhaven National Laboratory, Upton, New York 11973, USA.
authors.forename: Yu-Shin
authors.initials: YS
authors.lastname: Ding
authors.forename: Joanna S
authors.initials: JS
authors.lastname: Fowler
authors.forename: Jean
authors.initials: J
authors.lastname: Logan
authors.forename: Gene-Jack
authors.initials: GJ
authors.lastname: Wang
authors.forename: Frank
authors.initials: F
authors.lastname: Telang
authors.forename: Victor
authors.initials: V
authors.lastname: Garza
authors.forename: Anat
authors.initials: A
authors.lastname: Biegon
authors.forename: Deborah
authors.initials: D
authors.lastname: Pareto
authors.forename: William
authors.initials: W
authors.lastname: Rooney
authors.forename: Colleen
authors.initials: C
authors.lastname: Shea
authors.forename: David
authors.initials: D
authors.lastname: Alexoff
authors.forename: Nora D
authors.initials: ND
authors.lastname: Volkow
authors.forename: Frank
authors.initials: F
authors.lastname: Vocci
mesh_terms: D000328:Adult; D000818:Animals; D001384:Azetidines / Q000378:metabolism* / Q000493:pharmacokinetics; D001921:Brain / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000378:metabolism; D004341:Drug Evaluation; D004353:Drug Evaluation, Preclinical; D005260:Female; D005462:Fluorine Radioisotopes / Q000378:metabolism* / Q000493:pharmacokinetics; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000187:drug effects* / Q000378:metabolism; D010215:Papio; D011237:Predictive Value of Tests; D011849:Radioactive Tracers; D011978:Receptors, Nicotinic / Q000187:drug effects* / Q000378:metabolism; D015203:Reproducibility of Results; D013997:Time Factors; D014055:Tomography, Emission-Computed / Q000379:methods
chemical_list: C492928:6-fluoro-3-(2-azetidinylmethoxy)pyridine; C104288:A 85380; D001384:Azetidines; D005462:Fluorine Radioisotopes; D011849:Radioactive Tracers; D011978:Receptors, Nicotinic