title: Mid latency and slow vertex responses during pregnancy.
abstract: Central auditory pathways picked up electro-physiologically as mid latency responses (MLRs) and slow vertex responses (SVRs) have been studied least in women during their critical periods of life although auditory brainstem responses (ABRs) have been studied by many researchers. In the present study MLRs and SVRs were recorded in 20 pregnant women of age group 18-28 years. Their period of gestation ranged between 26-40 weeks and pregnancy had been uneventful and normal. MLRs and SVRs were recorded from Cz-A1 and Cz-A2 positions with alternating 90 dB sound pressure click stimuli delivered at 5 Hz and 0.5 Hz respectively. 256 stimuli for mid-latency and 64 stimuli for slow vertex responses were averaged and analyzed. Different waves of these auditory evoked responses were compared with 20 age matched non-pregnant females. The data obtained was analyzed for each variable by using unpaired student's T test. Present study did not reveal any difference in MLR waves during pregnancy when compared with the non-pregnant females whereas all the SVR waves were found to be significantly delayed in pregnant females. As SVR generators are found in different cortical areas, it can be said that auditory information processing at the higher centers is slow during pregnancy which in turn could be due to elevated levels of sex hormones specially estrogen and progesterone during pregnancy.
authors.affiliation: Department of Physiology, University College of Medical Sciences & GTB Hospital, Dilshad Garden, Delhi 110 095.
authors.forename: Asha
authors.initials: A
authors.lastname: Yadav
authors.forename: O P
authors.initials: OP
authors.lastname: Tandon
authors.forename: Neelam
authors.initials: N
authors.lastname: Vaney
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods; D000293:Adolescent; D000328:Adult; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D006801:Humans; D011247:Pregnancy / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology*