The antimicrobial activity of extracts of the lichen Cladonia foliacea and its (-)-usnic acid, atranorin, and fumarprotocetraric acid constituents.
The antimicrobial activity of the chloroform, diethyl ether, acetone, petroleum ether, and ethanol extracts of the lichen Cladonia foliacea and its (-)-usnic acid, atranorin, and fumarprotocetraric acid constituents against 9 bacteria and fungi has been investigated. The extracts and pure compounds alone were found active against the same bacteria and the same yeasts. Bacillus cereus, Bacillus subtilis, Staphylococcus aureus, Streptococcus faecalis, Proteus vulgaris, Listeria monocytogenes, Aeromonas hydrophila, Candida albicans, and Candida glabrata growth were inhibited. In addition, the MICs of the extracts, (-)-usnic acid, atranorin and fumarprotocetraric acid were determined.
Yilmaz
Meral
M
Anadolu University, Department of Biology, 26470 Eskisehir, Turkey.
Türk
Ayşen Ozdemir
AO
Tay
Turgay
T
Kivanç
Merih
M
D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001203:Ascomycota / Q000737:chemistry*; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D001572:Benzofurans / Q000302:isolation & purification* / Q000494:pharmacology; D002175:Candida / Q000187:drug effects* / Q000254:growth & development; D002855:Chromatography, Thin Layer; D005650:Fumarates / Q000302:isolation & purification* / Q000494:pharmacology; D062385:Hydroxybenzoates / Q000302:isolation & purification* / Q000494:pharmacology; D008011:Lichens / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000890:Anti-Infective Agents; D001572:Benzofurans; D005650:Fumarates; D062385:Hydroxybenzoates; D010936:Plant Extracts; C073339:usnic acid; C026304:atranorin; C026307:fumarprotocetraric acid