Relation of intimal hyperplasia thickness to stent size in paclitaxel-coated stents.
To determine the relation of intimal hyperplasia thickness to stent size in nonpolymeric paclitaxel-coated stents, intravascular ultrasound was performed after stent implantation and at 6 months. Similar to bare metal stents, this study demonstrated that intimal hyperplasia thickness is independent of stent size. There was no deleterious effect of the increased concentration associated with using the same stent design in a smaller artery, and these results suggested that stent strut density may be a more important concept than drug concentration.
Escolar
Esteban
E
Department of Medicine, University of Ulsan College of Medicine, Seoul, South Korea.
Mintz
Gary S
GS
Hong
Myeong-Ki
MK
Lee
Cheol Whan
CW
Kim
Jae-Joong
JJ
Fearnot
Neal E
NE
Park
Seong-Wook
SW
Park
Seung-Jung
SJ
Weissman
Neil J
NJ
D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage*; D006801:Humans; D006965:Hyperplasia; D017239:Paclitaxel / Q000008:administration & dosage*; D011474:Prosthesis Design; D016032:Randomized Controlled Trials as Topic; D015607:Stents; D017539:Tunica Intima / Q000000981:diagnostic imaging / Q000473:pathology*; D018084:Ultrasonography, Interventional
D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel