Free radical changes in methanol toxicity.
Role of free radicals in methanol toxicity was evaluated in methanol treated albino rats. Methanol intoxication increased lipid peroxidation and depleted the free radical scavenging enzyme systems. The free radical quenching effect of vitamin E protected the animals from methanol induced free radical damage.
Paula
Esther M
EM
Department of Physiology, Dr. AML Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai.
Mathangi
D C
DC
Namasivayam
A
A
D000818:Animals; D005260:Female; D005494:Folic Acid Deficiency / Q000378:metabolism; D016166:Free Radical Scavengers / Q000378:metabolism; D005609:Free Radicals / Q000378:metabolism*; D017665:Hydroxyl Radical / Q000378:metabolism; D007274:Injections, Intraperitoneal; D015227:Lipid Peroxidation / Q000187:drug effects / Q000502:physiology; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D000432:Methanol / Q000008:administration & dosage / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar; D014810:Vitamin E / Q000494:pharmacology
D016166:Free Radical Scavengers; D005609:Free Radicals; D014810:Vitamin E; D017665:Hydroxyl Radical; D000432:Methanol