title: Palladium-catalyzed reaction of 2-hydroxy-2-methylpropiophenone with aryl bromides: a unique multiple arylation via successive C-C and C-H bond cleavages.
abstract: 2-Hydroxy-2-methylpropiophenone undergoes a unique multiple arylation via C-C and C-H bond cleavages upon treatment with excess aryl bromides in the presence of a palladium catalyst to give 1,1,2,2-tetraarylethanes and 4,4-diaryl-1-phenylisochroman-3-ones.
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Wakui
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kawasaki
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Satoh
authors.forename: Masahiro
authors.initials: M
authors.lastname: Miura
authors.forename: Masakatsu
authors.initials: M
authors.lastname: Nomura
mesh_terms: D000478:Alkylation; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D006860:Hydrogen Bonding; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D011427:Propiophenones / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D006842:Hydrocarbons, Brominated; D011427:Propiophenones; D010165:Palladium; D002244:Carbon; C492094:2-hydroxy-2-methylpropiophenone