title: Chronic abdominal complaints and Helicobacter pylori in a Haitian population.
abstract: The objective of this study was to examine demographic, clinical, and pathologic variables, including Helicobacter pylori infection and malignancy, associated with chronic abdominal pain in a rural Haitian population. One hundred four patients underwent esophagogastroduodenoscopy, with biopsy only in those with gross findings. Associations between demographic, clinical, and pathologic variables were examined using the chi-square test. P values less than or equal to 0.05 were considered statistically significant. The majority (n = 66; 63%) required biopsy. Of these, 62% were positive for H. pylori. The associations between (1) chest complaints and esophageal disease, (2) female gender and benign esophageal disease, and (3) chronic active gastritis and presence of H. pylori were significant. There was one malignancy. H. pylori gastritis was common; malignancy was rare. Demographic and clinical variables poorly predicted pathologic diagnosis, which is consistent with previous studies. Further study is needed to assess the influence of other variables, including the African enigma, on disease progression in this population.
authors.forename: Sharon C
authors.initials: SC
authors.lastname: Kiely
authors.forename: Dana M
authors.initials: DM
authors.lastname: Grzybicki
authors.forename: Antonia
authors.initials: A
authors.lastname: Sepulveda
authors.forename: Marc
authors.initials: M
authors.lastname: Capitano
authors.forename: Elizabeth J
authors.initials: EJ
authors.lastname: Toborowsky
mesh_terms: D015746:Abdominal Pain / Q000175:diagnosis / Q000209:etiology*; D001706:Biopsy; D044383:Black People; D002908:Chronic Disease; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005756:Gastritis / Q000150:complications / Q000175:diagnosis; D005770:Gastrointestinal Neoplasms / Q000150:complications / Q000175:diagnosis; D006205:Haiti / Q000453:epidemiology; D016481:Helicobacter Infections / Q000150:complications / Q000175:diagnosis* / Q000208:ethnology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012017:Referral and Consultation; D012423:Rural Health