Genetic relatedness and quinolone resistance of Campylobacter jejuni strains isolated in 2002 in Hong Kong.
Pulsed-field gel electrophoresis fingerprints of 98 Campylobacter jejuni isolates from patients (85) and chicken carcasses (13) in Hong Kong in 2002 demonstrated high genetic diversity. The prevalence of quinolone resistance among the isolates was 85.9%, and replacement of the threonine-86 residue in the gyrase subunit A was the major resistance mechanism.
Chu
Yiu-Wai
YW
Public Health Laboratory Services Branch, Centre for Health Protection, Department of Health, Hong Kong Special Adminisstrative Region, Shek Kip Mei, Kowloon, Hong Kong SAR, People's Republic of China. so_micro4@dh.gov.hk
Chu
Man-Yu
MY
Luey
Kit-Yee
KY
Ngan
Yin-Wa
YW
Tsang
Ka-Lok
KL
Kam
Kai-Man
KM
D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001483:Base Sequence; D016123:Campylobacter jejuni / Q000187:drug effects* / Q000235:genetics; D002645:Chickens / Q000382:microbiology; D002939:Ciprofloxacin / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data
D000890:Anti-Infective Agents; D002939:Ciprofloxacin