Novel (3,5-di-tert-butyl-2-hydroxy-phenylcarbamoyl)-alkanoic acids as potent antioxidants.
A series of novel phenolic antioxidants of amphiphilic structure has been synthesized. Investigations into the influence of aliphatic spacer length and nature of a hydrophilic anchor on the antioxidant activity allowed elucidating certain structure requirements for the membrane-addressed antioxidant designing.
Lodyato
Vladimir I
VI
Department of Chemistry of the Belarusian State University, Skaryna av., 4, 220050 Minsk, Belarus.
Yurkova
Irina L
IL
Sorokin
Viktor L
VL
Shadyro
Oleg I
OI
Dolgopalets
Vladimir I
VI
Kisel
Mikhail A
MA
D000473:Alkanes / Q000737:chemistry* / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology*; D015394:Molecular Structure; D013329:Structure-Activity Relationship
D000473:Alkanes; D000975:Antioxidants