title: Glyco-dependent nuclear import of glycoproteins, glycoplexes and glycosylated plasmids.
abstract: This short review deals with some properties of nuclear sugar-binding proteins also called nuclear lectins, the sugar-dependent nuclear import of neoglycoproteins and the attempts of using this pathway to enhance the nuclear import of plasmids in order to hopefully increase the expression of transferred genes.
authors.affiliation: Glycobiologie, Vectorologie et Trafic Intracellulaire, Centre de Biophysique Moléculaire, Centre National de la Recherche Scientifique, 1 rue Charles-Sadron, F-45071 Orléans Cedex 2, France. monsigny@cnrs-orleans.fr
authors.forename: Michel
authors.initials: M
authors.lastname: Monsigny
authors.forename: Christine
authors.initials: C
authors.lastname: Rondanino
authors.forename: Eric
authors.initials: E
authors.lastname: Duverger
authors.forename: Isabelle
authors.initials: I
authors.lastname: Fajac
authors.forename: Annie-Claude
authors.initials: AC
authors.lastname: Roche
mesh_terms: D000818:Animals; D001692:Biological Transport; D002467:Cell Nucleus / Q000378:metabolism*; D015316:Genetic Therapy; D006023:Glycoproteins / Q000378:metabolism*; D006031:Glycosylation; D006801:Humans; D037102:Lectins / Q000378:metabolism*; D008362:Mannosides; D008845:Microinjections; D010957:Plasmids / Q000378:metabolism*; D011761:Pyrrolidonecarboxylic Acid
chemical_list: D006023:Glycoproteins; D037102:Lectins; D008362:Mannosides; D011761:Pyrrolidonecarboxylic Acid