title: Three-dimensional anisotropy contrast imaging of gliomatosis cerebri: two case reports.
abstract: BACKGROUND
  Magnetic resonance imaging (MRI) can provide a preoperative diagnosis of gliomatosis cerebri, but the findings sometimes do not correspond with the clinical symptoms or histologic findings.
  
  
  METHODS
  Three-dimensional anisotropy contrast (3DAC) imaging was used to assess damage to the neuronal fibers in two patients with gliomatosis cerebri who presented with only mental deterioration. Conventional MRI depicted markedly abnormal findings consisting of widespread areas of abnormally high signal intensity in the corpus callosum and in the bilateral white matter in both cases. In contrast, 3-D AC imaging showed no abnormality except for small dark areas in the corpus callosum or white matter.
  
  
  CONCLUSIONS
  3-D AC imaging provides more accurate information about damage to the neuronal fibers in cases of gliomatosis cerebri than other MRI techniques.
authors.affiliation: Department of Neurosurgery, Iwate Medical University School of Medicine, 19-1 Uchimaru, Morioka, Iwate 020-8505, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Inoue
authors.forename: Kuniaki
authors.initials: K
authors.lastname: Ogasawara
authors.forename: Takaaki
authors.initials: T
authors.lastname: Beppu
authors.forename: Akira
authors.initials: A
authors.lastname: Ogawa
mesh_terms: D000368:Aged; D016880:Anisotropy; D003287:Contrast Media; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000592:standards; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018302:Neoplasms, Neuroepithelial / Q000175:diagnosis*; D009412:Nerve Fibers / Q000473:pathology
chemical_list: D003287:Contrast Media