Platinum concentration in silicone breast implant material and capsular tissue by ICP-MS.
Inductively coupled plasma-mass spectrometry (ICP-MS) was used to determine the concentration of platinum (Pt) in silicone breast implant gel (range, 0.26-48.90 microg g(-1) Pt; n=15), elastomer (range, 3.05-28.78 microg g(-1) Pt; n=7), double lumen (range, 5.79-125.27 microg g(-1) Pt; n=7), foam (range, 5.79-8.36 microg g(-1) Pt; n=2), and capsular tissue (range, 0.003-0.272 microg g(-1) Pt; n=15). The results show that very high levels of Pt are present in the encasing elastomer, double lumen, and foam envelope materials. Silicone breast implants can be a source of significant Pt exposure for individuals with these implants.
Maharaj
S V M
SV
Department of Chemistry, American University, Washington, DC 20016, USA. Maharaj@american.edu
D000328:Adult; D000368:Aged; D018427:Breast Implants; D003238:Connective Tissue / Q000737:chemistry*; D005260:Female; D006801:Humans; D013058:Mass Spectrometry / Q000295:instrumentation / Q000379:methods; D008875:Middle Aged; D010984:Platinum / Q000032:analysis*; D012680:Sensitivity and Specificity; D020034:Silicone Gels / Q000737:chemistry*
D020034:Silicone Gels; D010984:Platinum