title: Colon preparation for magnification endoscopy: a rapid novel approach.
abstract: OBJECTIVE
  Minute lesions in the colon are of increasing clinical interest. Conventional endoscopic techniques are inadequate for visualizing these lesions, and magnification chromoendoscopy is required to identify them. This study compared the effectiveness of a simpler colon preparation method with the standard technique. Patients and Methods : Seven patients received dilute methylene blue (0.05 %) by enema prior to the endoscopic evaluation. The extent, quality, and ease of dye delivery were compared with the standard methods.
  
  
  RESULTS
  Dye delivery by enema extended to the splenic flexure and was uniformly applied, and advancement of the endoscope was easier. This alternative method was better tolerated by patients (visual analogue scale 1.9 +/- 0.3 vs. 3.8 +/- 0.8; P = 0.004).
  
  
  CONCLUSIONS
  This rapid and reliable method of visualizing the entire left colon with dye magnification allows magnification chromoendoscopy to be carried out in a convenient manner that is also less painful for the patient.
authors.affiliation: Dept. of Medicine, University of Illinois at Chicago/Chicago Veterans' Administration Medical Center (West Side Division), 840 South Wood Street (M/C 787), Chicago, IL 60612, USA. rcarroll@uic.edu
authors.forename: R E
authors.initials: RE
authors.lastname: Carroll
mesh_terms: D003106:Colon / Q000473:pathology; D003113:Colonoscopy / Q000379:methods*; D004396:Coloring Agents / Q000008:administration & dosage*; D004733:Enema; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008751:Methylene Blue / Q000008:administration & dosage*
chemical_list: D004396:Coloring Agents; D008751:Methylene Blue