[Pharmacokinetics and dose adaptation of ofloxacine, pefloxacine and ciprofloxacine during haemodialysis and continuous ambulatory peritoneal dialysis].
Fluoroquinolones present various pharmacokinetic properties. That's the way we carried out a bibliographic summary about the pharmacokinetics of pefloxacin, ofloxacin and ciprofloxacin in patients hit by chronic renal failure, under haemodialysis or under continuous ambulatory peritoneal dialysis. Then, we will describe how to adapt drug dose according to the degree of renal insufficiency and the used molécule.
Daniel
J-P
JP
Service stérilisation, hôpital E. Muller, 20, rue du Dr Laennec, BP 1370, F 68070 Mulhouse Cedex. DANIELJ@ch-mulhouse.fr
Moulin
B
B
Christmann
D
D
D000890:Anti-Infective Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics*; D002939:Ciprofloxacin / Q000008:administration & dosage* / Q000493:pharmacokinetics*; D024841:Fluoroquinolones / Q000008:administration & dosage* / Q000493:pharmacokinetics*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism*; D015242:Ofloxacin / Q000008:administration & dosage* / Q000493:pharmacokinetics*; D010531:Peritoneal Dialysis, Continuous Ambulatory; D006435:Renal Dialysis; D015366:Pefloxacin
D000890:Anti-Infective Agents; D002939:Ciprofloxacin; D024841:Fluoroquinolones; D015242:Ofloxacin; D015366:Pefloxacin