title: The Effectiveness of Systemp.desensitizer in the treatment of dentine hypersensitivity.
abstract: OBJECTIVE
  This study reports the effectiveness of Systemp.desensitizer (Ivoclar Vivadent, Schaan, Liechtenstein), when used both with and without an acid-etch step, in the treatment of patients with dentine hypersensitivity in UK dental practices.
  
  
  METHODS
  Ten general dental practitioners (GDPs) were selected from two practice-based research groups. The GDPs were each requested to use Systemp.desensitizer in the treatment of at least ten patients who presented with pain due to dentine hypersensitivity. Systemp.desensitizer was applied to the sensitive dentine area in strict accordance with the manufacturer's handling instructions, except that the patients were divided into two groups. For the first, group NE, the procedure was to isolate the tooth, gently blot it dry with cotton wool pellets, rub Systemp.desensitizer into the tooth for 20 seconds, then gently air-dry it. For the second, group E, the procedure was identical except that after isolation, the treatment area was etched for 15 seconds with 35% phosphoric acid. Patients were asked to complete a pro forma using a 10 cm visual analogue scale designed to provide details of the extent of their pain before treatment, 24 hours post-treatment, one week post-treatment, one month post-treatment, and three months post-treatment. The zero end of the scale was marked 'no pain' and the 10 cm end was marked 'extreme pain'. The percentage change in the patients' perception of their pain, relative to pretreatment, was calculated using repeated measures analysis and suitable follow-up confidence intervals for the mean changes in perceived pain. Comparisons were then made between the treatment groups NE and E.
  
  
  RESULTS
  Ninety-one patients completed the first pro forma and 77 completed all the pro formas. Overall, there was a significant reduction in pain at each of the time points after treatment but the pattern of pain reduction across the two groups was different. In general, the non-etched group (group NE) saw an 'immediate' reduction in pain which was then fairly consistent across the longer term, whilst, in general, the etched group (group E) saw less reduction in pain 24 hours after treatment, and then further reduction in pain at both one week and one month after treatment. Thus the non-etched group experienced an early reduction whilst the etched group took longer to perceive a reduction in pain; however, there were no statistically significant differences between the reductions in pain scores between the two groups at any of the time points after treatment.
  
  
  CONCLUSIONS
  It is concluded that Systemp.desensitizer was effective in reducing pain from dentine hypersensitivity in the patients treated, and this finding was unaffected by whether or not the tooth was acid-etched prior to application of the reagent.
authors.affiliation: Conservative Dentistry, University of Birmingham School of Dentistry, Birmingham, UK.
authors.forename: Dominic A
authors.initials: DA
authors.lastname: Stewardson
authors.forename: Russell J
authors.initials: RJ
authors.lastname: Crisp
authors.forename: Siobhan
authors.initials: S
authors.lastname: McHugh
authors.forename: Urs
authors.initials: U
authors.lastname: Lendenmann
authors.forename: F J Trevor
authors.initials: FJ
authors.lastname: Burke
mesh_terms: D000134:Acid Etching, Dental; D000328:Adult; D003807:Dentin Sensitivity / Q000188:drug therapy*; D004338:Drug Combinations; D005976:Glutaral / Q000627:therapeutic use*; D006801:Humans; D008689:Methacrylates / Q000627:therapeutic use*; D010147:Pain Measurement; D013997:Time Factors
chemical_list: D004338:Drug Combinations; D008689:Methacrylates; C489334:Systemp.desensitizer; D005976:Glutaral