Resource and hardware options for microarray-based experimentation.
DNA microarray technology permits the study of biological systems and processes on a genome-wide scale. Arrays based on cDNA clones, oligonucleotides and genomic clones have been developed for investigations of gene expression, genetic analysis and genomic changes associated with disease. Over the past 3-4 years, microarrays have become more widely available to the research community. This has occurred through increased commercial availability of custom and generic arrays and the development of robotic equipment that has enabled array printing and analysis facilities to be established in academic research institutions. This brief review examines the public and commercial resources, the microarray fabrication and data capture and analysis equipment currently available to the user.
Affara
Nabeel A
NA
Department of Pathology, University of Cambridge, UK. na106@cam.ac.uk
D019295:Computational Biology; D004247:DNA / Q000032:analysis*; D018076:DNA, Complementary / Q000235:genetics; D020869:Gene Expression Profiling / Q000295:instrumentation* / Q000379:methods* / Q000639:trends; D015894:Genome, Human; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis / Q000295:instrumentation* / Q000379:methods* / Q000639:trends; D010597:Pharmacogenetics; D011786:Quality Control
D018076:DNA, Complementary; D004247:DNA