Epidemiological investigation of bloodstream infections by extended spectrum cephalosporin-resistant Escherichia coli in a Taiwanese teaching hospital.
In an epidemiologic and case-control study including 30 case patients over a 3.5-year period in a Taiwanese university hospital, only beta-lactamase inhibitor use and extended-spectrum cephalosporin use were identified as independent risk factors for nosocomial CMY-2-producing Escherichia coli bloodstream infection, and CMY-2 producers were found more prevalent than extended-spectrum beta-lactamase-producing isolates.
Yan
Jing-Jou
JJ
Department of Pathology, National Cheng Kung University Hospital, 138 Sheng-Li Rd., Tainan, Taiwan 70428. jingjou@mail.ncku.edu.tw
Ko
Wen-Chien
WC
Wu
Jiunn-Jong
JJ
Tsai
Shu-Huei
SH
Chuang
Chin-Luan
CL
D000328:Adult; D000368:Aged; D016470:Bacteremia / Q000453:epidemiology / Q000209:etiology*; D016022:Case-Control Studies; D018550:Cephalosporin Resistance; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D008297:Male; D008875:Middle Aged; D019105:Random Amplified Polymorphic DNA Technique; D012307:Risk Factors; D013624:Taiwan / Q000453:epidemiology; D001618:beta-Lactamases / Q000096:biosynthesis*
C103022:beta-lactamase CMY-2; D001618:beta-Lactamases