title: [Etiology of nocturia and clinical efficacy of naftopidil on nocturia in patients with benign prostatic hyperplasia--analysis of frequency volume charts].
abstract: The etiology of nocturia in 70 patients with benign prostatic hyperplasia (BPH) who had nocturia of two or more times were examined based on frequency volume charts (FVC). Nocturia was classified into four groups: nocturnal polyuria, low capacity, combined nocturia, and no evidence of abnormality. Nearly half of the cases had nocturnal polyuria only. A little under 70% of patients had associated nocturnal polyuria (nocturnal polyuria+combined nocturia). Naftopidil was administered for three months to the patients with BPH who had nocturia with a urinary frequency of two or more times. Clinical efficacy was evaluated in 32 patients based on FVC and naftopidil was shown to improve nocturia. The improvement in nocturia was determined by the increment in voided volume.
authors.affiliation: Masuda Clinic.
authors.forename: Mitsunobu
authors.initials: M
authors.lastname: Masuda
authors.forename: Koichi
authors.initials: K
authors.lastname: Nakayama
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Hiromoto
authors.forename: Makoto
authors.initials: M
authors.lastname: Hirokawa
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Satomi
authors.forename: Miki
authors.initials: M
authors.lastname: Shiramizu
authors.forename: Akihiko
authors.initials: A
authors.lastname: Furuhata
authors.forename: Akiyoshi
authors.initials: A
authors.lastname: Ikeda
authors.forename: Chihiro
authors.initials: C
authors.lastname: Kawasaki
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D000368:Aged; D000369:Aged, 80 and over; D002940:Circadian Rhythm; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D008875:Middle Aged; D009281:Naphthalenes / Q000627:therapeutic use*; D010879:Piperazines / Q000627:therapeutic use*; D011470:Prostatic Hyperplasia / Q000150:complications*; D014554:Urination; D014555:Urination Disorders / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology
chemical_list: D000317:Adrenergic alpha-Antagonists; D009281:Naphthalenes; D010879:Piperazines; C064357:naftopidil