Palladium-catalyzed enantioselective ring opening of oxabicyclic alkenes with organozinc halides.
Palladium-catalyzed asymmetric ring opening of oxabenzonorbornadienes with readily available organozinc halides under mild conditions in the presence of (S)-Pr(i)-PHOX produces the corresponding 1,2-dihydronaphth-1-ols in good yield and high enantioselectivity. [reaction: see text]
State Key Laboratory of Organometallic Chemistry and Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China.
Ming
M
Li
Xiao-Xia
XX
Yan
Wei
W
Hong
Xia-Zhen
XZ
Zhu
Bo-Xun
BX
Cao
Jie
J
Sun
Xue-Long
XL
Hou