Hemiconvulsion-hemiplegia syndrome and primary human herpesvirus 7 infection.
We report a case of hemiconvulsion-hemiplegia (HH) syndrome. An 18-month-old female infant had a hemiconvulsion followed by left hemiplegia. Magnetic resonance imaging immediately after the onset of hemiplegia showed high intensity in the right hemisphere in diffusion-weighted images (DWI), while T1- and T2-weighted images were normal. Single photon emission computed tomography showed hypoperfusion of the right hemisphere in the acute phase. Virological analyses proved primary human herpesvirus 7 (HHV-7) infection. DWI are useful for the early evaluation of HH syndrome. Vascular disorders due to HHV-7 infection may have been related to the development of HH syndrome in this patient.
Department of Pediatrics, Okazaki City Hospital, Okazaki, Aichi, Japan. k-kawada@qa2.so-net.ne.jp
Jun-Ichi
J
Kawada
Hiroshi
H
Kimura
Tetsushi
T
Yoshikawa
Masaru
M
Ihira
Akihisa
A
Okumura
Tsuneo
T
Morishima
Fumio
F
Hayakawa
D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000473:pathology / Q000503:physiopathology / Q000821:virology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006429:Hemiplegia / Q000473:pathology / Q000503:physiopathology / Q000821:virology*; D016199:Herpesvirus 7, Human / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D020244:Infarction, Middle Cerebral Artery / Q000473:pathology / Q000503:physiopathology / Q000821:virology; D020768:Middle Cerebral Artery / Q000473:pathology / Q000503:physiopathology / Q000821:virology; D049268:Positron-Emission Tomography; D019349:Roseolovirus Infections / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D012640:Seizures / Q000473:pathology / Q000503:physiopathology / Q000821:virology*; D020293:Vasculitis, Central Nervous System / Q000473:pathology / Q000503:physiopathology / Q000821:virology*