Rosetting.
Why do some individuals get severe falciparum malaria while others don't? Rosetting (the binding of uninfected erythrocytes to Plasmodium falciparum-infected erythrocytes), together with endothelial cytoadherence, has been shown to play a crucial role in the obstruction of the microvosculoture in P. falciparum malaria. Here, Mats Wahlgren, Victor Fernandez, Carin Scholonder and Johan Carlson review the literature surrounding rosetting.
Wahlgren
M
M
Microbiology and Tumorbiology Center, Karolinska Institutet, Stockholm, Sweden.
Fernandez
V
V
Scholander
C
C
Carlson
J
J