Highly enantioselective copper-catalyzed conjugate addition of diethylzinc to nitroalkenes.
Copper-catalyzed asymmetric conjugate addition of diethylzinc to nitroalkenes using new chiral monodentate phosphoramidite ligands proceeds with high enantioselectivity up to 99% ee. [reaction: see text]
Department of Chemistry, State University of New York at Stony Brook, Stony Brook, New York 11794-3400.
Hojae
H
Choi
Zihao
Z
Hua
Iwao
I
Ojima
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D008024:Ligands; D009574:Nitro Compounds / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D009943:Organophosphorus Compounds / Q000737:chemistry*; D013237:Stereoisomerism
D000475:Alkenes; D008024:Ligands; D009574:Nitro Compounds; D009942:Organometallic Compounds; D009943:Organophosphorus Compounds; C434331:phosphoramidite; D003300:Copper; C454811:diethylzinc