Acupuncture and Chinese herbal medicine in the treatment of patients with seasonal allergic rhinitis: a randomized-controlled clinical trial.
BACKGROUND
Patients with allergic rhinitis (AR) increasingly use complementary medicine. The aim of this study was to determine whether traditional Chinese therapy is efficacious in patients suffering from seasonal AR.


METHODS
Fifty-two patients between the ages of 20 and 58 who had typical symptoms of seasonal AR were assigned randomly and in a blinded fashion to (i) an active treatment group which received a semi-standardized treatment of acupuncture and Chinese herbal medicine, and (ii) a control group which received acupuncture applied to non-acupuncture points in addition to a non-specific Chinese herbal formula. All patients received acupuncture treatment once per week and the respective Chinese herbal formula as a decoction three times daily for a total of 6 weeks. Assessments were performed before, during, and 1 week after treatment. The change in severity of hay fever symptoms was the primary outcome measured on a visual analogue scale (VAS).


RESULTS
Compared with patients in the control group, patients in the active treatment group showed a significant after-treatment improvement on the VAS (P = 0.006) and Rhinitis Quality of Life Questionnaire (P = 0.015). Improvement on the Global Assessment of Change Scale was noted in 85% of active treatment group participants vs 40% in the control group (P = 0.048). No differences between the two groups could be detected with the Allergic Rhinitis Symptom Questionnaire. Both treatments were well-tolerated.


CONCLUSIONS
The results of this study suggest that traditional Chinese therapy may be an efficacious and safe treatment option for patients with seasonal AR.
Department of Medicine I, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen Germany.
B
B
Brinkhaus
J
J
Hummelsberger
R
R
Kohnen
J
J
Seufert
C-H
CH
Hempen
H
H
Leonhardy
R
R
Nögel
S
S
Joos
E
E
Hahn
D
D
Schuppan
D015670:Acupuncture Therapy / Q000009:adverse effects; D000328:Adult; D004365:Drugs, Chinese Herbal / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D011788:Quality of Life; D006255:Rhinitis, Allergic, Seasonal / Q000523:psychology / Q000628:therapy*; D016037:Single-Blind Method
D004365:Drugs, Chinese Herbal