2-D graphical representation of proteins based on virtual genetic code.
We consider a novel 2-D graphical representation of proteins in which individual nucleic acids are represented as "spots" within a square frame distributed according to specific construction rules. The resulting "images" of proteins can not only serve to facilitate visual comparison of similarities and dissimilarities between lengthy protein sequences, but also offer a way for mathematical characterization of protein sequences, analogous to similar considerations for lengthy DNA sequences. Basically the approach is based on the concept of virtual genetic code, which is a hypothetical string of RNA nucleic acid bases, A, C, U and G, which generates reported protein sequences, without the knowledge of the actual genetic code that produces the protein.
Randić
M
M
National Institute of Chemistry, Ljubljana, Slovenia. mrandic@msn.com
D003196:Computer Graphics; D004247:DNA; D006801:Humans; D008962:Models, Theoretical; D009696:Nucleic Acids; D009710:Nucleotide Mapping; D011506:Proteins; D017422:Sequence Analysis, DNA; D020539:Sequence Analysis, Protein; D014584:User-Computer Interface
D009696:Nucleic Acids; D011506:Proteins; D004247:DNA