Development of a compact MRI system for trabecular bone volume fraction measurements.
A compact MRI system for measuring trabecular bone volume fraction (TBVF) of the calcaneus was developed with the use of a 0.21 T permanent magnet and portable MRI console. The entire system weighed < 600 kg and was installed in a 2 m x 2 m space. Two cross-sectional spin-echo images of a heel acquired with external reference phantoms (total measurement time = 5 min) were used to quantify the TBVF of the calcaneus. The linearity and reproducibility of the measurements were evaluated by means of proton density-adjusted phantoms. Comparative measurements with quantitative ultrasound (QUS) in groups of healthy female volunteers showed a relatively high positive correlation (R(2) = 0.4539, 0.2693) between TBVF and the speed of sound (SOS). These results demonstrate the potential of this new system for measuring bone density. Magn Reson Med 52:440-444, 2004.
Institute of Applied Physics, University of Tsukuba, Tsukuba, Japan. kose@bk.tsukuba.ac.jp
Katsumi
K
Kose
Yoshimasa
Y
Matsuda
Takeaki
T
Kurimoto
Seitarou
S
Hashimoto
Yukako
Y
Yamazaki
Tomoyuki
T
Haishi
Shin
S
Utsuzawa
Hiroshi
H
Yoshioka
Shigemasu
S
Okada
Masaaki
M
Aoki
Tsuyoshi
T
Tsuzaki
D000293:Adolescent; D000328:Adult; D015519:Bone Density; D002111:Calcaneus / Q000033:anatomy & histology*; D004867:Equipment Design; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D008875:Middle Aged; D019047:Phantoms, Imaging; D015203:Reproducibility of Results