Human T-cell responses to malaria: mostly forgotten or committed to memory?
T cells have been implicated in both malaria immunity and malaria disease and factors controlling the maintenance of T-cell responses over time may alter the clinical outcome o f infection. Michael Good and Janine Bilsborough have compared the T-cell responses to epitopes from the Plasmodium vivax and P. falciparum circumsporozoite proteins and here discuss the issue of T-cell memory as it applies to malaria.
Molecular Immunology Laboratory, Malaria and Arbovirus Unit, The Queensland Institute of Medical Research, 300 Herston Road, Brisbane, Queensland 4029, Australia.
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