Emerging asymmetry and embryonic patterning in early mouse development.
Recent studies have revealed asymmetries in the mouse zygote and preimplantation embryo, well before the establishment of anterior-posterior polarity after implantation. Whether these asymmetries are causally related to embryonic patterning or are coincidental outcomes of the topology of normal development remains uncertain.
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, 600 University Avenue, Ontario M5G 1X5, Canada. rossant@mshri.on.ca
Janet
J
Rossant
Patrick P L
PP
Tam
D000818:Animals; D001755:Blastocyst / Q000502:physiology; D019521:Body Patterning; D002467:Cell Nucleus / Q000378:metabolism; D010064:Embryo Implantation; D005260:Female; D005775:Gastrula / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental; D051379:Mice; D008954:Models, Biological; D013997:Time Factors; D014599:Uterus / Q000502:physiology; D015053:Zygote / Q000502:physiology