[Progressive multifocal leukoencephalopathy confirmed by PCR for JC virus in cerebrospinal fluid: case report].
A case of progressive multifocal leukoencephalopathy (PML) is presented, with literature review. PML diagnosis and its differential diagnosis are presented, with emphasis on neuroradiology, cerebrospinal fluid analysis and polymerase chain reaction studies. The prognosis of PML is usually poor, with a median survival of 1-6 months. There is yet no proven effective treatment for this condition; HAART has become the standard of care for these patients.
Pasqualotto
Alessandro Comarú
AC
Serviço de Infectologia, Hospital Nossa Senhora da Conceição, Porto Alegre, RS, Brasil. acpasq@terra.com.br
de Mattos
Alice J Z
AJ
Rocha
Marineide Melo
MM
D017088:AIDS-Related Opportunistic Infections / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000821:virology; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007577:JC Virus / Q000302:isolation & purification*; D007968:Leukoencephalopathy, Progressive Multifocal / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000821:virology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D016133:Polymerase Chain Reaction