Interactions between the sympathetic nervous system and the cardiac natriuretic peptide system.
The sympathetic nervous system (SNS) and the cardiac natriuretic peptide system (NPS) are fundamentally important neurohumoral systems for cardiovascular regulation. Their mutual interactions have been subject to numerous experimental and human studies. In the current manuscript, results from in vivo and in vitro studies will be reviewed with a focus on sympathetic outflow on the control of natriuretic peptide release.
Klinik und Poliklinik für Innere Medizin II, Klinikum der Universität Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg 93042, Germany. andreas.luchner@klinik.uni-regensburg.de
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D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000818:Animals; D009320:Atrial Natriuretic Factor / Q000097:blood / Q000378:metabolism* / Q000627:therapeutic use; D017704:Baroreflex / Q000187:drug effects; D002311:Cardiomyopathy, Dilated / Q000188:drug therapy / Q000378:metabolism*; D004730:Endothelium, Vascular / Q000378:metabolism; D006801:Humans; D007668:Kidney / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism*; D011941:Receptors, Adrenergic / Q000378:metabolism; D017461:Receptors, Atrial Natriuretic Factor / Q000187:drug effects / Q000378:metabolism; D013564:Sympathetic Nervous System / Q000187:drug effects / Q000378:metabolism*
D000319:Adrenergic beta-Antagonists; D011941:Receptors, Adrenergic; D009320:Atrial Natriuretic Factor; D017461:Receptors, Atrial Natriuretic Factor