[The compatibility of ronidazol in racing pigeons in a controlled clinical study].
Ronidazol is often used in racing pigeons for the treatment of Trichomonas infections and diseases. Therefore, in this study, the compatibility of the drug was examined by oral application over 7 days. For this purpose a randomized blind study was performed using four different groups (control group, 10 mg = therapy-group, 20 mg = double-dose-group and 40 mg = high-dose-group) of pigeons (Columba livia f. domestica) with 6 male and 6 female birds each. All birds were clinically healthy and between 6 and 12 weeks of age. The application of ronidazol at a dose of 10 mg/racing pigeon did show no side-effect within the duration of the study, e.g. no influence could be seen on clinical, haematological, blood-chemical and pathological parameters. Low-to middle-grade clinical alterations of the gastro-intestinal tract occurred in the high-dose group at day 6 and 7 of the application of the drug. Therefore a fourfold overdosing of ronidazol should be avoided.
Klinik für Kleintiere, Universität Leipzig.
M E
ME
Krautwald-Junghanns
R
R
Streubel
V
V
Schmidt
A
A
Richter
H J
HJ
Zumbusch
N
N
Lohmann
A
A
Daugschies
D000284:Administration, Oral; D000818:Animals; D000981:Antiprotozoal Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D000994:Antitrichomonal Agents / Q000494:pharmacology / Q000627:therapeutic use; D001715:Bird Diseases / Q000188:drug therapy*; D010856:Columbidae; D004305:Dose-Response Relationship, Drug; D005260:Female; D008297:Male; D012385:Ronidazole / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D016896:Treatment Outcome; D014244:Trichomonas / Q000187:drug effects; D014245:Trichomonas Infections / Q000188:drug therapy / Q000662:veterinary*
D000981:Antiprotozoal Agents; D000994:Antitrichomonal Agents; D012385:Ronidazole