[Expressions of bFGF, ET-1 and SCF in dermal papilla cells and the relation to their biological properties].
To investigate the expression of bFGF, ET-1 and SCF in different passages of cultured dermal papilla cells (DPC), and their possible effect on biological behaviour of DPC.



The expression of bFGF, ET-1 and SCF in different passages of cultured DPC was detected by immunocytochemistry and in situ hybridization.



The expression of ET-1 and SCF in early passages of cultured DPC was stronger, but became negative in late passages (>6 passages). The stronger the expression of ET-1 and SCF in DPC, the higher ability of DPC to induce hair follicle regeneration.



The expression strength of ET-1 and SCF is related to the ability of DPC inducing hair follicle regeneration.
Lu
Zhong-fa
ZF
Department of Dermatology, the Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China.
Wu
Jin-jin
JJ
Liu
Rong-qing
RQ
Zhong
Bai-yu
BY
Zheng
Min
M
D019332:Endothelin-1 / Q000032:analysis* / Q000235:genetics; D016222:Fibroblast Growth Factor 2 / Q000032:analysis* / Q000235:genetics; D018859:Hair Follicle / Q000737:chemistry* / Q000166:cytology / Q000502:physiology; D006801:Humans; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D019089:Stem Cell Factor / Q000032:analysis* / Q000235:genetics
D019332:Endothelin-1; D019089:Stem Cell Factor; D016222:Fibroblast Growth Factor 2