Expression of Caenorhabditis elegans mRNA in n Xenopus oocytes: a model system to study the mechanism of action of avermectins.
It has recently been shown that Xenopus oocytes injected with mRNA from the free-living nematode Caenorhabditis elegans express avermectin-sensitive chloride channels. Joseph Arena here reviews what is known about the mechanism of action of avermectin and how these recent results relate to the mechanism in nematodes.
Arena
J P
JP
Merck Research Laboratories, Department of Cell Biochemistry and Physiology, Rahway, NJ 07065-0900, USA.