Neonatal lower motor neuron syndrome associated with maternal neuropathy with anti-GM1 IgG.
The authors report a newborn with motor neuropathy associated with anti-GM1 antibodies from an affected mother. This finding suggests that the disorder was due to transplacental transfer of pathogenic antibodies.
Department of Neurology and Neuromuscular Disorders, University Hospital La Timone, 264 rue Saint-Pierre, Marseille, 13385, France. sattarian@ap-hm.fr
S
S
Attarian
J Ph
JP
Azulay
B
B
Chabrol
N
N
Escande-Beillard
J
J
Pouget
J
J
Boucraut
D000328:Adult; D000918:Antibody Specificity; D005260:Female; D005677:G(M1) Ganglioside / Q000276:immunology*; D006801:Humans; D007112:Immunity, Maternally-Acquired; D007074:Immunoglobulin G / Q000276:immunology*; D007231:Infant, Newborn; D007518:Isoantibodies / Q000276:immunology*; D008431:Maternal-Fetal Exchange; D016472:Motor Neuron Disease / Q000151:congenital* / Q000276:immunology; D009431:Neural Conduction; D010265:Paraproteinemias / Q000276:immunology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*
D007074:Immunoglobulin G; D007518:Isoantibodies; D005677:G(M1) Ganglioside