Initial endoscopic management of pineal region tumors and associated hydrocephalus: clinical series and literature review.
OBJECTIVE
The authors report their experience in six patients with pineal tumors and associated hydrocephalus who underwent an endoscopic biopsy procedure and third ventriculocisternostomy (ETVC) in a single sitting.


METHODS
The ETVC was successfully performed without complication in all patients; however, a ventriculoperitoneal shunt was eventually required in four. Histological diagnosis was successfully established in four patients. The authors also reviewed the literature to assess reports involving ETVC and tumor biopsy sampling in patients with pineal tumors and hydrocephalus. A total of 54 cases, including those in this study, have been reported. Fifteen percent of the patients eventually required placement of a ventricular shunt. The transient complication rate was 15% with no death. A positive tissue diagnosis was established in 89% of the cases overall.


CONCLUSIONS
The authors conclude that the endoscopic management of patients with pineal region masses and hydrocephalus may be a preferred initial strategy.
Sections of Pediatric Neurosurgery and Pediatric Hematology-Oncology, University of Chicago Children's Hospital, University of Chicago, Illinois 60637, USA. byamini@surgery.bsd.uchicago.edu
Bakhtiar
B
Yamini
Daniel
D
Refai
Charles M
CM
Rubin
David M
DM
Frim
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D004724:Endoscopy; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000601:surgery*; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D010870:Pineal Gland; D010871:Pinealoma / Q000150:complications / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome; D014696:Ventriculostomy