Structural organization of the genome of SARS-associated coronavirus (Strain SoD) isolated on the territory of the Russian Federation.
Complete nucleotide cDNA sequence (29715 nucleotides) of SARS-associated coronavirus (strain SoD) isolated for the first time in the territory of the Russian Federation was determined. Phylogenetic analysis revealed maximum similarity between strain SoD genome and Frankfurt 1 strain genome. Three nucleotide substitutions determining two amino acid substitutions were detected.
State Institute of Physico-Chemical Medicine, Ministry of Health of Russian Federation, Moscow, Russia. pathol@cyber.ma.nsc
G G
GG
Onishchenko
V M
VM
Govorun
V I
VI
Sergienko
T A
TA
Akopian
K T
KT
Momynaliev
V A
VA
Vereshchagin
V N
VN
Lazarev
N T
NT
Vasilev
V I
VI
Markov
V A
VA
Merkulov
V A
VA
Maksimov
V A
VA
Melnikov
Yu M
YM
Lopukhin
D019943:Amino Acid Substitution; D018076:DNA, Complementary / Q000235:genetics; D004279:DNA, Viral / Q000235:genetics; D016679:Genome, Viral; D006801:Humans; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D012426:Russia; D045473:Severe acute respiratory syndrome-related coronavirus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D045169:Severe Acute Respiratory Syndrome / Q000821:virology
D018076:DNA, Complementary; D004279:DNA, Viral