Human Plasmodium liver stages in SCID mice: a feasible model?
In a recent issue of Parasitology Today, Stanley and Virgin have stressed the potential of B- and T-cell deficient mice, among which severe combined immunodeficiency (SCID) mice are most frequently used, as models for the study of parasites. One of the most tantalizing prospects has been in the development of liver stages (LS) of human Plasmodium.
Bio-medical Parasitology, Pasteur Institute, 28 rue du Dr Roux, 75015 Paris, France.
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