Live attenuated vaccines against avian coccidiosis: Success with precocious and egg-adapted lines of Eimeria.
Avian coccidiosis, caused by parasites of the genus Eimeria, is a major disease of intensively reared poultry. Anticoccidial drugs, and vaccines based on live wild-type (virulent) parasites, have aided the management of coccidiosis, but the development of vaccines based on live attenuated parasites has been a significant advance. Here, Martin Shirley and Petr Bedrník explain the basis of these recent vaccines and discuss their use.
Institute for Animal Health, Compton Laboratory, Compton, Nr Newbury, Berkshire, UK. shirley@bbsrc.ac.uk
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