Pathomorphology of vascular bed in different variants of arrhythmogenic heart development.
A total of 200 hearts from patients with various forms of cardiosclerosis and pronounced disorders of the heart rhythm were examined postmortem by contrast polypositional cardioventriculography, coronarography, volume and weight cardiometry, and morphometry. Left-ventricular, right-ventricular, and septal variants of arrhythmogenic heart development were distinguished. Left-ventricular variant is characterized by compensatory restructuring of the vascular bed with appreciably increased volume of vascular density mainly in the left ventricle and with the median left type of blood supply. The right-ventricular variant is characterized by signs of compensation and decompensation of circulation and intensification of the right ventricular vascularization. The septal variant is characterized by signs of vascular bed decompensation with more intense vascularization of the septum. The detected diagnostic criteria indicate appreciable structural rearrangement of the coronary bed of arrhythmogenic heart, which explains the essential shifts in stimulation, contraction, and mechanical characteristics of the heart ventricles.
Department of General Pathology and Pathomorphology, State Institute of Regional Pathology and Pathomorphology, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk. pathol@cyber.ma.nsc
V D
VD
Rozenberg
L M
LM
Nepomnyashchikh
D001145:Arrhythmias, Cardiac / Q000209:etiology / Q000473:pathology*; D003331:Coronary Vessels / Q000473:pathology*; D006346:Heart Septum / Q000473:pathology; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D009929:Organ Size