Malignant transformation of a benign enchondroma of the hand to secondary chondrosarcoma with isolated pulmonary metastasis.
Malignant transformation of solitary enchondromas of the hand to secondary chondrosarcomas is extremely rare. We report a case of a recurrent chondromatous tumor of the hand that initially presented with the typical histology of a cellular enchondroma of the small tubular bones but with clinical and radiological signs of malignancy. After development of a single pulmonary metastasis of a chondromyxoid tumor a malignant transformation of the primary enchondroma of the hand must be assumed.
Department of Orthopaedics, Universitätsklinikum Grosshadern, Ludwig-Maximilians-Universität München, Germany. peter.mueller@med.uni-muenchen.de
P E
PE
Müller
H R
HR
Dürr
A
A
Nerlich
C
C
Pellengahr
M
M
Maier
V
V
Jansson
D002471:Cell Transformation, Neoplastic; D002812:Chondroma / Q000473:pathology*; D002813:Chondrosarcoma / Q000473:pathology* / Q000556:secondary*; D005260:Female; D006225:Hand; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary*; D008875:Middle Aged