Cytotoxicities of a 4-META/MMA-TBBO resin against human pulp fibroblasts.
This study was designed to investigate the cytotoxicity of MMA (methyl methacrylate) and 4-META (4-methacryloyloxyethoxycarbonylphthalic anhydride)/MMA with or without TBBO (tri-n-butylborane partially oxide), an initiator and TBBO alone against human pulp fibroblasts (HPF). Cell viabilities were measured by MTT assay. The cytotoxicity of 4-META/MMA-TBBO was comparable with that of MMA-TBBO. TBBO showed higher cytotoxicity than 4-META/MMA. The cytotoxicity induction of a 4-META/MMA-TBBO resin may be preferably associated with TBBO.
Department of Oral Diagnosis, Meikai University School of Dentistry, Keyakidai, Sakado, Saitama, Japan. fujisawa@dent.meikai.ac.jp
Seiichiro
S
Fujisawa
Toshiko
T
Atsumi
D000180:Acrylic Resins / Q000633:toxicity; D001896:Boron Compounds / Q000633:toxicity*; D002675:Child, Preschool; D003782:Dental Pulp / Q000166:cytology / Q000187:drug effects*; D005260:Female; D005347:Fibroblasts / Q000187:drug effects; D006801:Humans; D008768:Methylmethacrylates / Q000633:toxicity*; D019279:Resin Cements / Q000633:toxicity*
C476988:4-methacryloxyethyltrimellitic acid-methylmethacrylate-tributylborane; D000180:Acrylic Resins; D001896:Boron Compounds; D008768:Methylmethacrylates; D019279:Resin Cements; C009523:tri-n-butylborane; C031172:4-META resin