Painful neuropathy vasculitis in 2 patients with long-standing human immunodeficiency virus-1 infection.
We describe 2 most unusual cases of distal symmetrical painful polyneuropathy in patients with long-standing HIV-1 infection well controlled by HAART. Sural nerve biopsies revealed vasculitis in both cases and steroid therapy led to resolution of symptoms not influenced by analgesics and anti-inflammatory drugs. These unusual cases outline the importance of nerve biopsies in order to reach a diagnosis.
Sections of Clinical Neurology, Department of Neurological and Visual Sciences, University of Verona, Verona, Italy.
Sergio
S
Ferrari
Massimiliano
M
Lanzafame
Federica
F
Faggian
Marina
M
Malena
Mario
M
Cruciani
Tiziana
T
Cauallaro
Nicola
N
Rizzutol
Ercole
E
Concia
Sandro
S
Vento
D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D005500:Follow-Up Studies; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D008134:Long-Term Care; D008297:Male; D010146:Pain / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D010147:Pain Measurement; D011115:Polyneuropathies / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014657:Vasculitis / Q000150:complications / Q000175:diagnosis*
D011241:Prednisone