Myrrh (Commiphora molmol) in treatment of human and sheep dicrocoeliasis dendriticum in Saudi Arabia.
Dicrocoeliasis dendriticum is now imposing itself as an animal and zoonotic helminthic disease in many Arabian countries. Myrrh extract of Commiphora molmol (Mirazid) successfully and safely treated clinically and parasitologically proven 18 human dicrocoeliasis dendriticum patients. The dose was 2 capsules (300 mg each) given on an empty stomach an hour before the breakfast for six successive days. Cure (100%) was achieved clinically and by stool analysis for two months follow up. Besides, fifteen sheep naturally infected with Dicrocoelium dendriticum as proven parasitologically were successfully and safely treated with 2 capsules (300 mg each) on an empty stomach an hour before breakfast for four successive days. Cure (100%) was successfully achieved by stool analysis for seven days and macroscopically for detection of any adult worm after being slaughtered. The total dose required to treat infected sheep (2400 mg) was less than that required for human treatment (3600 mg).
Department of Zoology, College of Science for Girls, Dammam, King Abdel-Aziz University, P.O. Box 80205, Jeddah 21589, Saudi Arabia. mathalem@hotmail.com
Ebtesam M
EM
Al-Mathal
Mahmoud A H
MA
Fouad
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000818:Animals; D004011:Dicrocoeliasis / Q000188:drug therapy*; D004013:Dicrocoelium / Q000254:growth & development*; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D008297:Male; D012529:Saudi Arabia; D012756:Sheep; D013729:Terpenes / Q000627:therapeutic use*; D015047:Zoonoses / Q000469:parasitology*
D013729:Terpenes; C014119:myrrh oil