Scalloping of duodenal mucosa in Crohn's disease.
Scalloping of the duodenal mucosal folds is an endoscopic finding of small bowel mucosal pathology that is generally due to villous atrophy. Though it can be seen in many disease processes, it is most commonly associated with celiac disease. We report three patients with scalloping of duodenal folds and histologic confirmation of villous atrophy due to Crohn's disease. All patients had negative celiac serologies and two had positive markers for Crohn's disease (anti-Saccharomyces cerevisiae antibodies). Patients had either ileitis or ileocolitis in addition to duodenal abnormalities. These cases illustrate that scalloping can occur in the duodenum in Crohn's disease.
Culliford
Andrea
A
Department of Surgical Pathology and Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA.
Markowitz
David
D
Rotterdam
Heidrun
H
Green
Peter H R
PH
D000328:Adult; D000368:Aged; D003424:Crohn Disease / Q000150:complications / Q000473:pathology*; D004384:Duodenoscopy; D004386:Duodenum / Q000473:pathology*; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology*; D008875:Middle Aged