Modeling and experimental comparison of the differential adsorption of B1 and G1 aflatoxins on mineral aluminosilicate surfaces.
Aflatoxins produced by Aspergillus fungus are secondary metabolites undergoing biotransformation rates in hepatic tissues and lipid peroxidation. Although the use of adsorbent materials became a common practice for feed grain detoxification, fundamental studies are needed to clarify the interaction occurring between mineral surfaces and organic molecules. We evaluated the differential adsorption of B1 and G1 on 10 adsorbent materials and compared it in vitro by means of fluorescence emission from solution. Three aluminosilicates showed no adsorption of B1 at all, whereas only one was inactive for G1 adsorption and seven of them showed 15.2 to 77.9% adsorption for B1 and 8.3 to 78% for G1. All these adsorbents were more selective toward G1 rather than B1 aflatoxins. This behavior can be explained by the presence of an additional cyclic ester in G1, which provides a higher electronic density to G1 molecules, thus forming more stable hydrogen bridges with respect to the cyclopentanone ring present in B1.
Flores
C M
CM
Laboratorio de Morfologia, UNAM-Iztacala, Av. De Los Barrios S/N, Los Reyes Iztacala, Tlalnepantla, Mexico.
Domínguez
J M
JM
Díaz-De-León
J
J
D000327:Adsorption; D016604:Aflatoxin B1 / Q000737:chemistry / Q000493:pharmacokinetics*; D000348:Aflatoxins / Q000737:chemistry / Q000493:pharmacokinetics*; D000538:Aluminum Silicates / Q000737:chemistry / Q000493:pharmacokinetics*; D008958:Models, Molecular; D016060:Sorption Detoxification
D000348:Aflatoxins; D000538:Aluminum Silicates; C027955:aflatoxin G1; C049037:aluminosilicate; D016604:Aflatoxin B1