[Variability of HIV-1 viral load in patients cared along 4 years].
BACKGROUND
Analysis of the variations of HIV-1 viral load (VL) in a cohort of patients.


METHODS
A retrospective study was designed for the calculation and analysis of the differences between two consecutive measurements of VL in a cohort of 1,336 patients along a 48 months follow-up.


RESULTS
At the beginning of the follow-up period the highest proportion of patients with decreases of VL (54.2% in their first measurement, at 0-75 days) as well as the least proportion of patients both without changes (30.7%) and with increases of their VL (15.1%), were registered. The proportion of patients with decreases was declining along the study period. More than half of the patients did not experience significant variations in the measurements carried out.


CONCLUSIONS
The significant decreases of VL appeared in our series at the beginning of the follow-up period, and a growing proportion of individuals showed elevations of the VL along the period studied.
Hospital Clínico Universitario y Facultad de Medicina de Valladolid, Valladolid. eiros@med.uva.es
J M
JM
Eiros Bouza
M
M
Ortega Lafont
R
R
Ortiz de Lejarazu
P
P
Bachiller Luque
J A
JA
Gómez de Caso
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000821:virology*; D015497:HIV-1; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013997:Time Factors; D019562:Viral Load / Q000639:trends*