Cloning and expression of the Vitreoscilla hemoglobin gene in Enterobacter aerogenes: effect on cell growth and oxygen uptake.
The hemoglobins found in unicellular organisms show a greater chemical reactivity, protect cells against oxidative stress and hence have been implicated in a wider variety of potential functions than those traditionally associated with animal and plant hemoglobins. There are well-documented studies showing that bacteria expressing Vitreoscilla hemoglobin (VHb), the first prokaryotic hemoglobin characterized, have better growth and oxygen uptake rates than VHb counterparts.
Erendler
S O
SO
Department of Biology, Inonu University, Malatya, Turkey.
Gencer
S
S
Gecckil
H
H
Stark
B C
BC
Webster
D A
DA
D001426:Bacterial Proteins / Q000235:genetics; D002374:Catalase / Q000032:analysis / Q000378:metabolism; D003001:Cloning, Molecular; D021902:Enterobacter aerogenes / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D015870:Gene Expression; D006420:Hemeproteins / Q000235:genetics; D006454:Hemoglobins / Q000032:analysis / Q000096:biosynthesis / Q000235:genetics*; D010100:Oxygen / Q000032:analysis; D010101:Oxygen Consumption; D011994:Recombinant Proteins / Q000096:biosynthesis; D013482:Superoxide Dismutase / Q000032:analysis / Q000378:metabolism; D020589:Vitreoscilla / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism
D001426:Bacterial Proteins; D006420:Hemeproteins; D006454:Hemoglobins; D011994:Recombinant Proteins; C100771:Vgb protein, Bacteria; D002374:Catalase; D013482:Superoxide Dismutase; D010100:Oxygen