[Chemoprophylaxis and vaccine for prevention of bacterial meningitis in children].
Given the devastating nature of Neisseria meningitidis disease and emergence of resistant strains prevention through chemoprophylaxis and meningococcal vaccine remains the best approach to control this serious infection. Chemoprophylaxis may limited strictly to the contact subjects. Polysaccharide meningococcal serogroups A, C, Y and W135 should be given less than 10 days to patients with prolonged contact with the index case. Meningococcal C conjugate vaccine constitutes an additional advantage in the prevention of meningococcal meningitis in children < 2 years. High Haemophilus serotype B coverage level led to near-disappearance of H. influenzae serotype b meningitis but chemoprophylaxis remains indicated.
Service de pédiatrie générale, hôpital Robert Debré, 75019 Paris. antoine.bourrillon@rdb.ap-hop-paris.fr
Antoine
A
Bourrillon
Edouard
E
Bingen
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D017714:Community-Acquired Infections / Q000517:prevention & control; D006801:Humans; D007223:Infant; D016920:Meningitis, Bacterial / Q000517:prevention & control*; D022401:Meningococcal Vaccines
D000900:Anti-Bacterial Agents; D022401:Meningococcal Vaccines