Arginine revisited: minireview article.
Arginine is a precursor of proteins and employed in urea synthesis. It is also the precursor of many other compounds, such as creatine, nitric oxide, polyamines, agmatine, proline. In this review, its transport and that of other basic amino acids are examined, along with its transformation into nitric oxide, agmatine and proline, and the mutual regulation of the individual pathways.
Dipartimento di Medicina e Oncologia Sperimentale, Sezione di Biochimica, Università di Torino, Torino, Italy. sebastiano.colombatto@unito.it
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D000376:Agmatine / Q000378:metabolism; D026923:Amino Acid Transport Systems, Basic / Q000378:metabolism; D000818:Animals; D001119:Arginase / Q000378:metabolism; D001120:Arginine / Q000378:metabolism*; D006801:Humans; D009569:Nitric Oxide / Q000378:metabolism; D011392:Proline / Q000378:metabolism
D026923:Amino Acid Transport Systems, Basic; D009569:Nitric Oxide; D000376:Agmatine; D001120:Arginine; D011392:Proline; D001119:Arginase