Decrease in prefrontal hemoglobin oxygenation during reaching tasks with delayed visual feedback: a near-infrared spectroscopy study.
Visual feedback of hand movement is crucial to accurate reaching. Although previous studies have extensively examined spatial alteration of visual feedback (e.g., prism adaptation), temporal delay of visual feedback has been less explored. In the present study, we investigated the effect of delayed visual feedback of the moving hand in a reaching task. The prefrontal cortical activity was measured by near-infrared spectroscopy (NIRS). Twelve subjects performed reaching tasks under two conditions where visual feedback of their own hand was delayed by 200 ms (delay condition) or 0 ms (normal condition). Introducing the visual feedback delay significantly disrupted the reaching performance, although the subjects gradually adapted to the delay during the experiment. There was a clear tendency to overreach the target in the delay condition, even after the reaching movement had been practiced sufficiently in the normal condition. We observed marked oxy- and total-Hb decreases in the dorsal prefrontal area in the delay conditions. The decrease began shortly after task onset and diminished during the rest period, indicating that the decrease was task-induced. Furthermore, the oxy- and total-Hb decreases were significantly correlated with task performance--the degree of decrease was larger as the subject made more errors. We suggest that the decreases in oxy- and total-Hb at the dorsal prefrontal area are related with the visuomotor recalibration process.
PRESTO, Japan Science and Technology Corporation, Japan. shimada@ardbeg.c.u-tokyo.ac.jp
Sotaro
S
Shimada
Kazuo
K
Hiraki
Goh
G
Matsuda
Ichiro
I
Oda
D000328:Adult; D005246:Feedback / Q000502:physiology; D005260:Female; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D008297:Male; D010100:Oxygen / Q000097:blood*; D010108:Oxyhemoglobins / Q000378:metabolism; D017397:Prefrontal Cortex / Q000098:blood supply / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology*; D019265:Spectroscopy, Near-Infrared; D014796:Visual Perception / Q000502:physiology
D006454:Hemoglobins; D010108:Oxyhemoglobins; D010100:Oxygen