(-)-Amarbellisine, a lycorine-type alkaloid from Amaryllis belladonna L. growing in Egypt.
A new lycorine-type alkaloid, named (-)-amarbellisine, was isolated from the bulbs of Egyptian Amaryllis belladonna L. together with the well known alkaloids (-)-lycorine, (-)-pancracine, (+)-vittatine, (+)-11-hydroxyvittatine, and (+)-hippeastrine. The new alkaloid, containing the pyrrolo[de]phenanthridine ring system, was essentially characterised by spectroscopic and optical methods, and proved to be the 2-methoxy-3a,4,5,7,11b,11c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridinol. By using HPTLC technique we also carried out a comparative study of the relative and total alkaloidal content at two different stages of plant growth. Finally, the antimicrobial activity of the isolated alkaloids was assayed.
Evidente
Antonio
A
Dipartimento di Scienze del Suolo della Pianta e dell'Ambiente, Università di Napoli Federico II, Via Università 100, I-80055 Portici, Italy. evidente@unina.it
Andolfi
Anna
A
Abou-Donia
Amina H
AH
Touema
Soad M
SM
Hammoda
Hala M
HM
Shawky
Eman
E
Motta
Andrea
A
D047151:Amaryllidaceae Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004534:Egypt; D019668:Liliaceae / Q000737:chemistry* / Q000254:growth & development; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
D047151:Amaryllidaceae Alkaloids