[The study on expression of bFGF and quantity of mast cell in infant hemangiomas of grandulae parotid gland].
The qualitative and quantitative study on mast cells and bFGF in 40 cases of infant hemangiomas of the grandulae parotid and 5 cases of normal grandulae parotid tissues were investigated by special mast cell staining methods, immunohistochemistry and image analysis technique. The quantity, area and average density of MC remarkably increased, there were significant differences. The mast cells mainly distributed around premature blood vessels and in parotid gland leaves; bFGF was highly expressed in infant hemangiomas of grandulae parotid. Its immuno-reactivity was present in the cytoplasm of endotheliocytes,mainly in extracellular matrix, distributed in light reticulation. It is concluded that there was a close relationship between bFGF and mast cell in proliferation of infant hemangiomas of grandulae parotid.
Department of Stomatology, Second Hospital, China Medical University, Shenyang 110004, Liaoning Province, China. Xiaoping_ba@yahoo.com
Xiao-Ping
XP
Lin
Wei-Xian
WX
Liu
Ji
J
Li
D005260:Female; D016222:Fibroblast Growth Factor 2 / Q000096:biosynthesis*; D006391:Hemangioma / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008407:Mast Cells / Q000473:pathology*; D010307:Parotid Neoplasms / Q000378:metabolism* / Q000473:pathology
D016222:Fibroblast Growth Factor 2