Learning channels. Cellular physiology of odor processing neurons within the honeybee brain.
To understand the cellular mechanisms of olfactory learning in the honeybee brain we study the physiology of identified neurons within the olfactory pathway. Here, we review data on the voltage-sensitive and ligand-gated ionic currents of mushroom body Kenyon cells and antennal lobe neurons in vitro and in situ. Both cell types generate action potentials in vitro, but have different voltage-sensitive K+ currents. They express nicotinic acetylcholine receptors and ionotropic GABA receptors, representing the major transmitter systems in the insect olfactory system. Our data are interpreted with respect to learning-dependent plasticity in the honeybee brain.
Institut für Biologie, Neurobiologie, Freie Universität Berlin, Königin-Luise-Str. 28-30, D-14195 Berlin, Germany. gruenewa@neurobiologie.fu-berlin.de
B
B
Grünewald
Anna
A
Wersing
D G
DG
Wüstenberg
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001516:Bees; D001921:Brain / Q000033:anatomy & histology* / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D007313:Insecta; D007477:Ions; D007858:Learning; D008024:Ligands; D008954:Models, Biological; D009474:Neurons / Q000378:metabolism / Q000502:physiology*; D009812:Odorants; D009830:Olfactory Bulb / Q000502:physiology; D018408:Patch-Clamp Techniques; D011188:Potassium / Q000378:metabolism; D011950:Receptors, Cholinergic / Q000378:metabolism; D018079:Receptors, GABA; D011978:Receptors, Nicotinic / Q000378:metabolism
D007477:Ions; D008024:Ligands; D011950:Receptors, Cholinergic; D018079:Receptors, GABA; D011978:Receptors, Nicotinic; D011188:Potassium