Reverse fluorous solid-phase extraction: a new technique for rapid separation of fluorous compounds.
Fluorous-tagged compounds can rapidly be separated from organic (non-tagged) compounds by the new separation technique of reverse fluorous solid-phase extraction (r-fspe). In a reversal of the roles of solid and liquid phases in standard fluorous spe, a mixture is charged to a polar solid phase (standard silica gel) and then eluted with a fluorous solvent or solvent mixture. The organic components of the mixture are retained, while the fluorous components pass. [structure: see text]
Matsugi
Masato
M
Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Curran
Dennis P
DP
D002850:Chromatography, Gel / Q000379:methods*; D017611:Fluorine Compounds / Q000737:chemistry / Q000302:isolation & purification*; D009930:Organic Chemicals / Q000302:isolation & purification*; D058428:Silica Gel; D012822:Silicon Dioxide; D012997:Solvents / Q000737:chemistry
D017611:Fluorine Compounds; D009930:Organic Chemicals; D012997:Solvents; D058428:Silica Gel; D012822:Silicon Dioxide