Absorption of acylated anthocyanins in rats and humans after ingesting an extract of Ipomoea batatas purple sweet potato tuber.
We evaluated the absorbability of anthocyanins in humans and rats administered with a beverage prepared from an extract of the tuber of purple sweet potato (Ipomoea batatas Cultivar Ayamurasaki), or with an anthocyanin concentrate. Two major anthocyanin components, cyanidin 3-O-(2-O-(6-O-(E)-caffeoyl-beta-D-glucopyranosyl)-beta-D-glucopyranoside)-5-O-beta-D-glucopyranoside) and peonidin 3-O-(2-O-(6-O-(E)-caffeoyl-beta-D-glucopyranosyl)-beta-D-glucopyranoside)-5-O-beta-D-glucopyranoside), were detected in the plasma and urine of both rats and humans by HPLC or liquid chromatography/mass spectrometry (LC/MS). The plasma concentration of anthocyanins in humans reached a maximum 90 minutes after ingestion, and the recovery of anthocyanins in the urine was estimated as 0.01-0.03%. These results indicate that acylated anthocyanins could be selectively absorbed after ingesting food.
Harada
Katsuhisa
K
Yakult Central Institute for Microbiological Research, 1796 Yaho, Kunitachi-shi, Tokyo 186-8560, Japan. katsuhisa-harada@yakult.co.jp
Kano
Mitsuyoshi
M
Takayanagi
Tomomi
T
Yamakawa
Osamu
O
Ishikawa
Fumiyasu
F
D000328:Adult; D000818:Animals; D000872:Anthocyanins / Q000097:blood* / Q000493:pharmacokinetics* / Q000652:urine*; D002851:Chromatography, High Pressure Liquid; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007408:Intestinal Absorption / Q000502:physiology; D027723:Ipomoea batatas / Q000737:chemistry*; D008297:Male; D010936:Plant Extracts / Q000737:chemistry / Q000493:pharmacokinetics; D051381:Rats; D017207:Rats, Sprague-Dawley
D000872:Anthocyanins; D010936:Plant Extracts; C103378:cyanidin 3-O-(6-O-caffeyl-2-O-glucopyranosyl-beta-glucopyranosyl)-5-O-glucoside; C103379:peonidin 3-O-(6-O-caffeyl-2-O-glucopyranosyl-beta-glucopyranosyl)-5-O-glucoside