The genetics of hypogammaglobulinemia.
Etiologies for human hypogammaglobulinemias are diverse and include genetic and nongenetic causes. Although recent reviews focus on the complex genetics of common variable immunodeficiency, in this review, we survey different causes of hypogammaglobulinemias and discuss possible mechanisms.
Division of Rheumatology and Clinical Immunology, Medical School, University of Freiburg, Germany. grimbacher@medizin.ukl.uni-freiburg.de
Bodo
B
Grimbacher
Alejandro A
AA
Schäffer
Hans-Hartmut
HH
Peter
D000361:Agammaglobulinemia / Q000235:genetics*; D017668:Age of Onset; D017074:Common Variable Immunodeficiency / Q000209:etiology / Q000235:genetics; D008040:Genetic Linkage; D006801:Humans; D017098:IgA Deficiency / Q000235:genetics; D017099:IgG Deficiency / Q000235:genetics