Early rapid rise in intraocular pressure after intravitreal triamcinolone acetonide injection.
OBJECTIVE
To report the occurrences of early rapid increases in intraocular (IOP) after intravitreal glucocorticoid injection.


METHODS
Observational case series.


METHODS
We retrospectively reviewed the records of three patients seen and treated at Duke Eye Center.


RESULTS
In all three cases, a significant rise in IOP occurred within 1 week of intravitreal triamcinolone injection for refractory macular edema. In one patient, a white material was found in the angle on gonioscopy. All three cases required surgical intervention to reduce the IOP.


CONCLUSIONS
Considering the early rapid rise in IOP in these three cases, we suggest that clinicians closely monitor patients after intravitreal triamcinolone injections for the development of acute glaucoma. Additionally, it may be advisable to perform gonioscopic examinations to look for any abnormal accumulation of material in the angle.
Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina, USA. inder.singh@mc.duke.edu
Inder P
IP
Singh
Sameer I
SI
Ahmad
David
D
Yeh
Pratap
P
Challa
Leon W
LW
Herndon
R Rand
RR
Allingham
Paul P
PP
Lee
D005938:Glucocorticoids / Q000009:adverse effects*; D006068:Gonioscopy; D006801:Humans; D007267:Injections; D007429:Intraocular Pressure / Q000187:drug effects*; D008269:Macular Edema / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000139:chemically induced*; D012189:Retrospective Studies; D014222:Triamcinolone Acetonide / Q000009:adverse effects*; D014822:Vitreous Body
D005938:Glucocorticoids; D014222:Triamcinolone Acetonide