SSD: sterol-sensing direct.
Cholesterol homeostasis is established by a complex of three proteins, one of which contains a hydrophobic domain previously termed a sterol-sensing domain. New biochemical studies of this domain demonstrate direct high-affinity binding of the sterol-sensing domain to sterol.
Levine
Tim
T
Division of Cell Biology, Institute of Ophthalmology, Bath Street, London EC1V 9EL, United Kingdom.
D000818:Animals; D002784:Cholesterol / Q000378:metabolism*; D004721:Endoplasmic Reticulum / Q000378:metabolism; D006056:Golgi Apparatus / Q000378:metabolism; D050356:Lipid Metabolism; D008954:Models, Biological; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D013261:Sterols / Q000378:metabolism
D013261:Sterols; D002784:Cholesterol