A case of quadruple cancer including urinary bladder, oral cavity, stomach and lung.
A 67-year-old man, who had smoked heavily for many years, was found in 1997 to have bladder tumors, and transurethral resection of the bladder tumor (TUR-Bt) was performed. Histopathological diagnosis was urothelial carcinoma (G2>G3, pTa, N0, M0, ly0, v0). In December, 1998, he noticed an oral cavity tumor. After preoperative radiation therapy (total 40 Gy, 17 times), surgical treatment was undertaken. Histopathological diagnosis was well differentiated squamous cell carcinoma (pT2, pN2b, M0). In February, 2000, gastric tumor was detected by endoscopic examination, and subtotal gastorectomy and Roux en Y operation were performed. Histopathological diagnosis was well differentiated adenocarcinoma (pT2, pN0, M0, P0, CY0). A chest computed tomographic (CT) scan revealed a solitary lung tumor in April, 2000. Partial peumonectomy was performed, and histopathological diagnosis was poorly differentiated adenocarcinoma (pT1, N0, M0, P0). In April, 2000, multiple lesions of bladder cancer in the neck of the urinary bladder and posterior urethra were found and radical cystoprostatourethrectomy combined with lymph node dissection and bilateral cutaneous ureterostomy were performed (urothelial carcinoma, G3, pT4a, pN2, M0, pL2, pV0, pR0). Since then, the patient has been followed carefully.
Mitsuhashi
Makoto
M
Department of Urology, Osaka City University Medical School.
Yoshimoto
Mitsuru
M
Matsuyama
Masahide
M
Ito
Satoshi
S
Wada
Seiji
S
Kiyota
Atsuhiko
A
Yoshimura
Rikio
R
Nakatani
Tatsuya
T
D000230:Adenocarcinoma / Q000601:surgery; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy / Q000601:surgery; D002295:Carcinoma, Transitional Cell / Q000601:surgery; D015653:Cystectomy; D005743:Gastrectomy; D006801:Humans; D008175:Lung Neoplasms / Q000601:surgery; D008297:Male; D009062:Mouth Neoplasms / Q000532:radiotherapy / Q000601:surgery; D009378:Neoplasms, Multiple Primary; D011013:Pneumonectomy; D012907:Smoking / Q000009:adverse effects; D013274:Stomach Neoplasms / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000601:surgery