Allocentric versus egocentric spatial memory after unilateral temporal lobectomy in humans.
Thirty patients who had undergone either a right or left unilateral temporal lobectomy (14 RTL; 16 LTL) and 16 control participants were tested on a computerized human analogue of the Morris Water Maze. The procedure was designed to compare allocentric and egocentric spatial memory. In the allocentric condition, participants searched for a target location on the screen, guided by object cues. Between trials, participants had to walk around the screen, which disrupted egocentric memory representation. In the egocentric condition, participants remained in the same position, but the object cues were shifted between searches to prevent them from using allocentric memory. Only the RTL group was impaired on the allocentric condition, and neither the LTL nor RTL group was impaired on additional tests of spatial working memory or spatial manipulation. The results support the notion that the right anterior temporal lobe stores long-term allocentric spatial memories.
University College London, London, United Kingdom.
Janet D
JD
Feigenbaum
Robin G
RG
Morris
D000328:Adult; D000679:Amygdala / Q000503:physiopathology; D038481:Anterior Temporal Lobectomy; D001931:Brain Mapping; D003463:Cues; D004292:Dominance, Cerebral / Q000502:physiology*; D005260:Female; D006624:Hippocampus / Q000503:physiopathology; D006801:Humans; D008297:Male; D018782:Maze Learning / Q000502:physiology; D008570:Memory, Short-Term / Q000502:physiology; D011939:Mental Recall / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D009949:Orientation / Q000502:physiology*; D011183:Postoperative Complications / Q000503:physiopathology*; D011340:Problem Solving / Q000502:physiology; D011597:Psychomotor Performance / Q000502:physiology; D012016:Reference Values; D012153:Retention, Psychology / Q000502:physiology*; D012931:Social Environment; D013028:Space Perception / Q000502:physiology*; D013702:Temporal Lobe / Q000503:physiopathology; D014584:User-Computer Interface