Randomization methods in clinical trials.
In recent times there has been an enormous growth in the number of randomized controlled trials (RCTs). Their importance for clinical practice is inarguable, so it is essential for the practitioner to acquire a basic knowledge of their methodology, in order to accurately evaluate this type of study. Randomization is a central concept, since it constitutes the basis for production of results that are valid, important and applicable. In this paper we set out to show the importance of randomization by explaining its basic concepts, its practical use, the different types available, and the best ways to put them into practice.
Centro de Estudos de Medicina Baseada na Evidência, Faculdade de Medicina de Lisboa, Portugal.
Domingos
D
Vaz
Laura
L
Santos
Micaela
M
Machado
António Vaz
AV
Carneiro
D016032:Randomized Controlled Trials as Topic / Q000379:methods* / Q000592:standards