Calcium hydroxyapatite ceramic implants in bone tumour surgery. A long-term follow-up study.
We reviewed the results of 51 patients with benign bone tumours treated by curettage and implantation of calcium hydroxyapatite ceramic (CHA). The mean follow-up was 11.4 years (10 to 15.5). Post-operative fractures occurred in two patients and three had local recurrences; three had slightly limited movement of the adjacent joint and one had mild osteoarthritis. There were no allergic or neoplastic complications. In all cases, radiographs showed that the CHA was well incorporated into the host bone. Statistical analysis showed that absorption of the implanted CHA was greater in males (odds ratio, 6.2; 95% CI, 1.6 to 23.7) and younger patients (odds ratio, 0.6 for increase in age of 10 years; 95% CI, 0.91 to 0.99). However, the implanted CHA was not completely absorbed in any patient. We conclude that CHA is a useful and safe bone substitute for the treatment of benign bone tumours.
Department of Orthopaedic Surgery, Mie University School of Medicine, Tsu-city, Japan.
A
A
Matsumine
A
A
Myoui
K
K
Kusuzaki
N
N
Araki
M
M
Seto
H
H
Yoshikawa
A
A
Uchida
D000293:Adolescent; D000328:Adult; D001672:Biocompatible Materials / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D018786:Bone Substitutes / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003475:Curettage / Q000379:methods; D017886:Durapatite / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D050723:Fractures, Bone / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000209:etiology; D016348:Osseointegration; D011183:Postoperative Complications / Q000209:etiology; D011859:Radiography; D012189:Retrospective Studies
D001672:Biocompatible Materials; D018786:Bone Substitutes; D017886:Durapatite