Intracerebroventricular administration of chicken motilin does not induce hyperphagia in meat-type chicks.
The effect of chicken motilin on food intake was investigated in meat-type chicks under ad libitum feeding, refeeding, and fasting conditions. We found that the intracerebroventricular injection of chicken motilin (0.1 and 0.2 microg) tended to increase food intake under ad libitum feeding and refeeding conditions at 60 min postinjection, but the differences were not significant (P>.05). On the other hand, central administration of chicken motilin (0.2 and 0.4 microg) showed a tendency to suppress feeding of fasted chicks as well as the result of high dose (5.0 microg) under ad libitum feeding conditions. Therefore, the results presented here suggest that central motilin alone does not induce hyperphagia in meat-type chicks.
Laboratory of Animal Science, Department of Agrobiological Science, Faculty of Agriculture, Ehime University, Matsuyama 790-8566, Japan. bungo@agr.ehime-u.ac.jp
Takashi
T
Bungo
Hiroshi
H
Ueda
Takio
T
Kitazawa
Tetsuro
T
Taneike
Mitsuhiro
M
Furuse
D000818:Animals; D001069:Appetite Regulation / Q000187:drug effects / Q000502:physiology*; D002645:Chickens; D004305:Dose-Response Relationship, Drug; D004435:Eating / Q000187:drug effects / Q000502:physiology; D005215:Fasting / Q000502:physiology*; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology*; D006963:Hyperphagia / Q000139:chemically induced / Q000503:physiopathology*; D007276:Injections, Intraventricular; D008297:Male; D009037:Motilin / Q000008:administration & dosage / Q000502:physiology*
D009037:Motilin