Acute transplant rejection induced by blood transfusion reaction to the Kidd blood group system.
Many renal transplant centres now try to avoid blood transfusion prior to renal transplantation, to avoid alloimmunization due to antibody production against donor antigens usually present on contaminating white cells. Post- or peri-operative transfusions are usually not considered to present problems, since the patient is heavily immunosuppressed. We present a patient who suffered a rare transfusion reaction, that we believe may have initiated a severe vascular rejection of a kidney transplant, probably mediated by Kidd blood group antigens.
Renal Unit, Brighton and Sussex University Hospitals, Royal Sussex County Hospital, Brighton BN2 5BE, UK. steve.holt@bsuh.nhs.uk
Stephen
S
Holt
Helen
H
Donaldson
Geoffrey
G
Hazlehurst
Zac
Z
Varghese
Marcela
M
Contreras
Edward
E
Kingdon
Paul
P
Sweny
Aine
A
Burns
D000208:Acute Disease; D000328:Adult; D005260:Female; D006084:Graft Rejection / Q000097:blood*; D006801:Humans; D007667:Kidd Blood-Group System; D016030:Kidney Transplantation / Q000009:adverse effects; D019520:Living Donors; D065227:Transfusion Reaction
D007667:Kidd Blood-Group System