[Trimetazidine-induced parkinsonism].
Eight patients, six women and two men, ages between 72 and 94 years (mean age 80), suffered from parkinsonism while taking trimetazidine, seven of them for a 6 to 12 months time period and the other for 9 years. The parkinsonism reverted after drug withdrawal. This is the first report of trimetazidine induced parkinsonism. It is important to know this side effect in order to avoid its administration to patients with any parkinsonism, especially those suffering dementia with Lewy bodies.
Martí Massó
J F
JF
Servicio de Neurología, Hospital de Donostia, Universidad del País Vasco, San Sebastián. jfmarti@chdo.osakidetza.net
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D010302:Parkinson Disease, Secondary / Q000139:chemically induced*; D014292:Trimetazidine / Q000009:adverse effects*
D014292:Trimetazidine