Monanchorin, a bicyclic alkaloid from the sponge Monanchora ungiculata.
Monanchorin, a guanidine alkaloid with an unusual bicyclic skeleton, together with the known pentacyclic alkaloid crambescidin acid have been isolated from the aqueous extract of the sponge Monanchoraungiculata.
Molecular Targets Development Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702-1201, USA.
Karina M
KM
Meragelman
Tawnya C
TC
McKee
James B
JB
McMahon
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification*; D000818:Animals; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D019791:Guanidine; D006146:Guanidines / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D008407:Mast Cells / Q000187:drug effects; D051379:Mice; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010140:Pacific Ocean; D011161:Porifera / Q000737:chemistry*
D000470:Alkaloids; D019086:Bridged Bicyclo Compounds, Heterocyclic; D006146:Guanidines; C488575:monanchorin; D019791:Guanidine