Antifungal activity of actinomycetes from Cuban soils.
This study reports on the capacity of actinomycete strains isolated from Cuban soils to produce antifungal agents. The antimicrobial activities were determined by susceptibility disk assay methods. We isolated 563 different actinomycetes and 286 produced compounds with antifungal activity. Our screening method indicated the presence of many possible polyene macrolide antibiotics and the important antifungal activity in the soils rich in minerals.
Biotechnology Department, Pharmaceutical Chemistry Center, Cubanacán, Havana, Cuba.
Y
Y
Iznaga
M
M
Lemus
L
L
González
L
L
Garmendía
L
L
Nadal
C
C
Vallín
D039903:Actinobacteria; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D003462:Cuba; D006801:Humans; D008826:Microbial Sensitivity Tests; D008847:Micromonospora / Q000187:drug effects; D008517:Phytotherapy; D012988:Soil Microbiology; D013302:Streptomyces / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents