Antiphospholipid and antisynthetase syndrome in a patient with polymyositis-rheumatoid arthritis overlap.
Idiopathic inflammatory myopathies, mainly polymyositis (PM) may occur in the course of several autoimmune diseases. The overlapping forms of myositis, when the patient also meets the criteria for rheumatoid arthritis (RA), affect 3%-5% of myositis patients [1]. To the best of our knowledge this is the first report on the overlapping form of RA, antiphospholipid syndrome (APS) and the serological subgroup of PM, the antisynthetase syndrome (ASS).
Division of Clinical Immunology, 3rd Department of Internal Medicine, Medical and Health Science Center, University of Debrecen, Hungary.
Andrea
A
Ponyi
Tamás
T
Constantin
Katalin
K
Dankó
D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D016572:Cyclosporine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006225:Hand / Q000473:pathology; D006801:Humans; D008025:Ligases / Q000276:immunology*; D008168:Lung / Q000000981:diagnostic imaging; D017563:Lung Diseases, Interstitial / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D017285:Polymyositis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D012074:Remission Induction; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D000974:Antibodies, Antinuclear; D005938:Glucocorticoids; C046750:Jo-1 antibody; D016572:Cyclosporine; D008025:Ligases