Cellular addresses; step one in creating a glycocode.
In this issue of Chemistry & Biology, a library screening approach reveals at least four types of enzymes that attach galactosamine to build cell surface mucin-type glycoproteins. A better molecular understanding of how these information-carrying oligosaccharides are created sets the stage for designing more selective inhibitors and potential therapeutics.
Department of Chemistry and the Plant Sciences Institute, Gilman Hall, Iowa State University, Ames, IA 50011, USA.
Nicola
N
Pohl
D004798:Enzymes / Q000378:metabolism*; D005688:Galactosamine / Q000378:metabolism
D004798:Enzymes; D005688:Galactosamine