A case of peanut cross-allergy to lupine flour in a hot dog bread.
BACKGROUND
In a case monitored by the Norwegian National Register for Severe Allergic Reactions to Food, a patient with peanut allergy experienced an allergic reaction after eating a particular brand of hot dog bread. The aim of this study was to identify the eliciting allergen.


METHODS
Extracts from the hot dog bread and reference material from peanut, lupine and lupine-fortified food products were analysed by immunochemical methods with patient serum and a new polyclonal anti-lupine antibody.


RESULTS
Evidence could be provided that the hot dog bread contained proteins from lupine but not from peanut.


CONCLUSIONS
Crossed peanut-lupine allergy can have clinical significance. A peanut-allergic patient reacted against hidden lupine protein in a hot dog bread. Presented with our results, the producer confirmed the use of lupine flour and changed the ingredient list.
Faeste
Christiane K
CK
National Veterinary Institute, PO Box 8156, NO-0033 Oslo, Norway. christiane.feste@vetinst.no
Løvik
Martinus
M
Wiker
Harald G
HG
Egaas
Eliann
E
D000328:Adult; D001939:Bread / Q000009:adverse effects*; D003429:Cross Reactions / Q000276:immunology*; D005260:Female; D005433:Flour / Q000009:adverse effects; D006801:Humans; D031297:Lupinus / Q000276:immunology*; D021183:Peanut Hypersensitivity / Q000276:immunology*