Effects of tiletamine/zolazepam-romifidine-atropine in ocelots (Leopardus pardalis).
OBJECTIVE
To evaluate the effects of a combination of tiletamine-zolazepam-romifidine-atropine in ocelots.


METHODS
Prospective experimental trial.


METHODS
Eight captive adult ocelots (three females and five males).


METHODS
Calculated doses of tiletamine-zolazepam (3.75 mg kg(-1)), romifidine (50 microg kg(-1)) and atropine (0.04 mg kg(-1)) were administered intramuscularly. After immobilization, animals were weighed and the real doses determined. Heart rate, respiratory frequency, noninvasive systolic, diastolic, and mean arterial pressure, arterial oxygen hemoglobin saturation, and rectal temperature were measured. Data were analyzed by means of anova for repeated measures, followed by the Tukey test to compare values over time.


RESULTS
Doses administered were 3.4 +/- 0.6 mg kg(-1) of tiletamine-zolazepam, 0.04 +/- 7.0 mg kg(-1) of romifidine, and 0.03 +/- 0.007 mg kg(-1) of atropine. The mean time to recumbency and duration of immobilization were 7.0 +/- 4.5 and 109.2 +/- 27.9 minutes, respectively. The median times to standing and walking were 52.3 [0-90] and 2.3 [0-69.3] minutes, respectively. A decrease in heart rate was observed 45 minutes following drug administration. Arterial blood pressure was maintained during the study.


CONCLUSIONS
This protocol produced good immobilization in ocelots with minimal changes over time in cardiovascular parameters.
Universidade Anhembi-Morumbi, Hospital Veterinàrio Anhembi-Morumbi, São Paulo, Brazil. andre_selmi@yahoo.com.br
André L
AL
Selmi
Juliana P
JP
Figueiredo
Guilherme M
GM
Mendes
Bruno T
BT
Lins
D000778:Anesthetics, Dissociative / Q000008:administration & dosage*; D000818:Animals; D001285:Atropine / Q000008:administration & dosage; D001794:Blood Pressure / Q000187:drug effects; D002335:Carnivora / Q000502:physiology*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D007093:Imidazoles / Q000008:administration & dosage; D007273:Injections, Intramuscular / Q000662:veterinary; D008297:Male; D009126:Muscle Relaxation / Q000187:drug effects; D010100:Oxygen / Q000097:blood; D011446:Prospective Studies; D012119:Respiration / Q000187:drug effects; D013992:Tiletamine / Q000008:administration & dosage; D015041:Zolazepam / Q000008:administration & dosage
D000778:Anesthetics, Dissociative; D007093:Imidazoles; D013992:Tiletamine; D001285:Atropine; C076257:romifidine; D015041:Zolazepam; D010100:Oxygen