Incidence of childhood leukaemia in the vicinity of nuclear sites in France, 1990-1998.
Overall, 670 cases (O) of childhood leukaemia were diagnosed within 20 km of the 29 French nuclear installations between 1990 and 1998 compared to an expected number (E) of 729.09 cases (O/E=0.92, 95% confidence interval (CI)=[0.85-0.99]). Each of the four areas defined around the sites showed non significant deficits of cases (0-5 km: O=65, O/E=0.87, CI=[0.67-1.10]; 5-10 km: O=165, O/E=0.95, CI=[0.81-1.10]; 10-15 km: O=220, O/E=0.88, CI=[0.77-1.00]; 15-20 km: O=220, O/E=0.96, CI=[0.84-1.10]). There was no evidence of a trend in standardised incidence ratio with distance from the sites for all children or for any of the three age groups studied. Similar results were obtained when the start-up year of the electricity-generating nuclear sites and their electric nuclear power were taken into account. No evidence was found of a generally increased risk of childhood leukaemia around the 29 French nuclear sites under study during 1990-1998.
Institut National de la Santé et de la Recherche Médicale INSERM - U170-IFR69, 16 avenue Paul Vaillant Couturier, 94807 Villejuif Cedex, France.
M L
ML
White-Koning
D
D
Hémon
D
D
Laurier
M
M
Tirmarche
E
E
Jougla
A
A
Goubin
J
J
Clavel
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007953:Leukemia, Radiation-Induced / Q000453:epidemiology*; D009688:Nuclear Reactors