Palladium-catalyzed enantioselective ring opening of oxabicyclic alkenes with organozinc halides.
Palladium-catalyzed asymmetric ring opening of oxabenzonorbornadienes with readily available organozinc halides under mild conditions in the presence of (S)-Pr(i)-PHOX produces the corresponding 1,2-dihydronaphth-1-ols in good yield and high enantioselectivity. [reaction: see text]
Li
Ming
M
State Key Laboratory of Organometallic Chemistry and Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China.
Yan
Xiao-Xia
XX
Hong
Wei
W
Zhu
Xia-Zhen
XZ
Cao
Bo-Xun
BX
Sun
Jie
J
Hou
Xue-Long
XL