Nevirapine-containing regimens in HIV-infected naive patients with CD4 cell counts of 200 cells/microl or less.
We retrospectively evaluated the effectiveness of nevirapine-containing regimens in 118 naive patients initiating highly active antiretroviral therapy with CD4 cell counts S 200 cells/jl. After 24 months, 51% of patients continued nevirapine, 43 and 83% had viral loads < 50 copies/ml by intent-to-treat and on-treatment analyses, and a mean increase of +246 CD4 cells/microl occurred. More than 80% of patients who continued with nevirapine had viral loads < 50 copies/ml and CD4 cell counts > 200 cells/pl.
Ferrer
Elena
E
Infectious Disease Services, Universitari de Bellvitge Hospital, Barcelona, Spain.
Santamariña
Elena
E
Domingo
Pere
P
Fumero
Emilio
E
Ribera
Esteban
E
Knobel
Hernando
H
Lopez
Juan Carlos
JC
Barrios
Ana
A
Podzamczer
Daniel
D
D019380:Anti-HIV Agents / Q000009:adverse effects / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects / Q000379:methods; D018791:CD4 Lymphocyte Count / Q000379:methods*; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D019829:Nevirapine / Q000009:adverse effects / Q000627:therapeutic use*; D012189:Retrospective Studies; D016896:Treatment Outcome; D019562:Viral Load
D019380:Anti-HIV Agents; D019829:Nevirapine