[Gastrin-secreting neuroendocrine carcinoma: two cases identified and treated surgically with a radio-guided technique].
The authors present two cases of gastrin-producing carcinoma demonstrated by scintigraphy with In-111 pentetreotide. The possible malignant evolution of such tumours and the good results that can be achieved with surgical therapy suggest the usefulness of a radio-guided intraoperative strategy to locate the lesions and minimise invasive procedures. This approach enabled us to detect a lymph-node metastasis concealed in the adipose tissue in the first case and to exclude any other gastrin-producing tumour localisations in the second. We recommend that the radio-guided strategy should be included among the guidelines for the treatment of gastrinomas and believe that the procedure can also be used in other functioning endocrine tumours.
Pandolfi
Umberto
U
U.O. di Chirurgia Generale, Presidio Ospedaliero di Vigevano, Azienda Ospedaliera della Provincia di Pavia.
Cossard
David
D
Pesenti Campagnoni
Arcangelo
A
Biandrate
Ferruccio
F
Piccolini
Marco
M
Francia
Luigi
L
Zadra
Francesca
F
Ambrosino
Giovanni
G
Rosa
Cesare
C
Battaglia
Antonio
A
Carena
Mauro
M
D000368:Aged; D004379:Duodenal Neoplasms / Q000473:pathology / Q000601:surgery*; D015408:Gastrinoma / Q000556:secondary / Q000601:surgery*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D018358:Neuroendocrine Tumors / Q000473:pathology / Q000601:surgery*; D010190:Pancreatic Neoplasms / Q000473:pathology / Q000601:surgery*; D016634:Radiosurgery; D016896:Treatment Outcome