Hydrochlorothiazide induced hepato-cholestatic liver injury.
Hydrochlorothiazide and other thiazide-like diuretics are considered as a first-line drug for initial therapy in uncomplicated arterial hypertension [1]. There are several reports [2-6] of thiazide-induced cholecystitis, but here we report a case of serious hepatotoxicity associated with hydrochlorothiazide treatment.
Meuhedet Health Care System, Netania, Israel. arinzon@walla.co.il
Zeev
Z
Arinzon
Peisakh
P
Alexander
Yitshal
Y
Berner
D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use / Q000633:toxicity*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D002780:Cholestasis, Intrahepatic / Q000139:chemically induced* / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use / Q000633:toxicity*; D006973:Hypertension / Q000188:drug therapy*; D008111:Liver Function Tests
D000959:Antihypertensive Agents; D006852:Hydrochlorothiazide