Sebaceous carcinoma ex-pleomorphic adenoma: a rare phenotypic occurrence.
Primary sebaceous carcinoma of salivary glands is a rare entity with approximately 22 de novo documented cases. Similar tumor arising in a benign mixed tumor has only been reported once. We report a second case of sebaceous carcinoma in a pleomorphic adenoma and discuss the clinicopathologic features, histogenesis, and the differential diagnosis of this unusual tumor.
Cohn
Michael L
ML
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA.
Callender
David L
DL
El-Naggar
Adel K
AK
D018266:Adenocarcinoma, Sebaceous / Q000473:pathology* / Q000601:surgery; D008949:Adenoma, Pleomorphic / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery; D010641:Phenotype; D012468:Salivary Gland Neoplasms / Q000473:pathology* / Q000601:surgery; D012626:Sebaceous Gland Neoplasms / Q000473:pathology* / Q000601:surgery