Insecticide susceptibility level of Anopheles arabiensis in two agrodevelopment localities in eastern Ethiopia.
Anopheles arabiensis strains reared from larvae and pupae collected from two different localities, Metehara and Melka-Worer, eastern Ethiopia, were evaluated against three insecticides. Resistance states of adult females were determined using the WHO test kits under field condition. The insecticides used were WHO discriminating doses of 4% DDT, 0.75% permethrin and 0.1% propoxur. The study revealed that 42.5% of the An. arabiensis population was resistant to DDT in Melka-Worer while only 30% of the species was resistant in Metehara to the same insecticide. In Metehara, 25% of An. arabiensis was also resistant to permethrin while the population was highly susceptible to the insecticide in Melka-Worer. Propoxur, which was not evaluated in Melka-Worer, was highly toxic to An. arabiensis in Metehara. The knocked-down time (KD50) for permethrin was 14.5 and 12.5 minutes in Metehara and Melka-Worer, respectively. The implications of these findings are discussed.
Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia. aau-ipb@telecom.net.et
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M
Balkew
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Gebre-Michael
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Hailu
D000818:Animals; D000852:Anopheles / Q000187:drug effects*; D003634:DDT / Q000494:pharmacology*; D005002:Ethiopia; D005260:Female; D007303:Insect Vectors / Q000187:drug effects; D007305:Insecticide Resistance; D007306:Insecticides / Q000494:pharmacology*; D007928:Lethal Dose 50; D009032:Mosquito Control; D010209:Paper; D026023:Permethrin / Q000494:pharmacology*; D001074:Propoxur / Q000494:pharmacology*
D007306:Insecticides; D026023:Permethrin; D001074:Propoxur; D003634:DDT