The transglutaminase family: an overview: minireview article.
The knowledge that very different processes such as normal and neoplastic cell growth, reproduction and death are dependent on the presence of adequate levels of transglutaminases (TGase: EC 2.3.2.13) and that they are capable of affecting the differentiation and proliferative capability of several cell types, has prompted a multitude of researchers to study these fascinating molecules. In the following overview we intend to summarize the currently known information on the biological significance of these enzymes.
Department of Biology, University of Rome Tor Vergata, Rome, Italy.
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D000818:Animals; D001709:Biotechnology; D001777:Blood Coagulation / Q000502:physiology; D016923:Cell Death; D004194:Disease; D004817:Epidermis / Q000201:enzymology; D006801:Humans; D010944:Plants / Q000201:enzymology; D011503:Transglutaminases / Q000737:chemistry / Q000378:metabolism*
D011503:Transglutaminases