Single-step recovery of ephedrine hydrochloride from raw materials using expanded bed adsorption.
Expanded bed adsorption, using a cation resin 001 x 7 Styrene-DVB, was used to recover and purify ephedrine hydrochloride from a powdered herb. The axial liquid-phase dispersion coefficient was about 10(-5) m(2) s(-1) and the recovery yield and purification reached 86% and 22, respectively. Compared with using conventional extraction with dimethylbenzene, this method is safer and also more efficient.
State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100080, P.O. Box 353, P.R. China. wdchen@home.ipe.ac.cn
Wei-Dong
WD
Chen
Yan-Dong
YD
Wang
Li-Hang
LH
Zha
Guang-Hui
GH
Ma
Zhi-Guo
ZG
Su
D002411:Cation Exchange Resins; D005591:Chemical Fractionation / Q000379:methods; D002845:Chromatography / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification*; D029789:Ephedra / Q000378:metabolism*; D004809:Ephedrine / Q000302:isolation & purification*; D014462:Ultrafiltration / Q000379:methods*
D002411:Cation Exchange Resins; D004365:Drugs, Chinese Herbal; D004809:Ephedrine