SelSim: a program to simulate population genetic data with natural selection and recombination.
SelSim is a program for Monte Carlo simulation of DNA polymorphism data for a recombining region within which a single bi-allelic site has experienced natural selection. SelSim allows simulation from either a fully stochastic model of, or deterministic approximations to, natural selection within a coalescent framework. A number of different mutation models are available for simulating surrounding neutral variation. The package enables a detailed exploration of the effects of different models and strengths of selection on patterns of diversity. This provides a tool for the statistical analysis of both empirical data and methods designed to detect natural selection.


BACKGROUND
http://www.stats.ox.ac.uk/mathgen/software.html.


BACKGROUND
http://www.stats.ox.ac.uk/mathgen/software.html.
Department of Statistics, 1 South Parks Road, Oxford OX1 3TG, UK. spencer@stats.ox.ac.uk <spencer@stats.ox.ac.uk>
Chris C A
CC
Spencer
Graham
G
Coop
D000818:Animals; D005075:Biological Evolution; D003198:Computer Simulation; D014644:Genetic Variation / Q000235:genetics*; D005828:Genetics, Population / Q000379:methods*; D006801:Humans; D008957:Models, Genetic; D015233:Models, Statistical; D011995:Recombination, Genetic / Q000235:genetics*; D012641:Selection, Genetic; D012984:Software