[New therapeutic approachs in melanoma].
During the last decade, new insights in cellular and molecular biology have opened new avenues in cancer immunotherapy. Two distinct modalities have been developed: adoptive immunotherapy and anti-tumoral vaccination (active immunotherapy). We will first describe the main strategies of adoptive immunotherapy and then elaborate on the protocols of anti-tumoral vaccination against tumor associated antigens (TAA). In that context, we will pay peculiar attention on the pivotal role of dendritic cells (DC) as natural adjuvant.
Mortier
L
L
Services d'Oncologie médicale, Hôpital Erasme, ULB.
Marchetti
P
P
Gordower
L
L
Charbonnier-Hatzfeld
A S
AS
Toungouz
M
M
Velu
T
T
D019496:Cancer Vaccines / Q000627:therapeutic use*; D003713:Dendritic Cells / Q000276:immunology; D006801:Humans; D007167:Immunotherapy / Q000379:methods; D008545:Melanoma / Q000235:genetics / Q000276:immunology* / Q000628:therapy*
D019496:Cancer Vaccines