Synthesis of alpha-ketoamides from a carbamoylsilane and acid chlorides.
Treatment of acid chlorides with a carbamoylsilane affords alpha-ketoamides. In some instances, in situ reaction of additional carbamoylsilane with these products yielded alpha-organyl-alpha-siloxymalonamides.
Department of Chemistry and Biochemistry, Northern Illinois University, DeKalb, Illinois 60115, USA.
Jianxin
J
Chen
Robert F
RF
Cunico
D000577:Amides / Q000138:chemical synthesis*; D002712:Chlorides / Q000737:chemistry; D007659:Ketones / Q000138:chemical synthesis*; D015394:Molecular Structure; D012821:Silanes / Q000737:chemistry
D000577:Amides; D002712:Chlorides; D007659:Ketones; D012821:Silanes