A case of rhabdomyosarcoma of the vagina in an elderly woman.
Most rhabdomyosarcomas of the vagina (RMSV) occur in infants and children up to six years old. RMSV in elderly patients is extremely rare. We report a case of a 70-year-old woman with RMSV. She had received surgery for uterine endometrial cancer one year before and a vaginal polypoid tumor was noted during routine follow-up vaginal examination. She was referred to our department for radiation therapy following partial tumorectomy of the lesion. She was given three sessions of intra-vaginal radiation therapy, once a week with 6 Gy at 7.5 mm below the vaginal surface and external irradiation of 50 Gy to the pelvis. However, paraaortal lymph node metastasis developed during initial radiation therapy. Furthermore, multiple bone metastases appeared at the completion of the radiation therapy. Six months after initial treatment the patient died from progression of the disease. Autopsy demonstrated small residual tumor at the primary site as well as multiple systemic metastases.
Suzuki
Y
Y
Department of Radiation Oncology, Gunma University, Graduate School of Medicine, Gunma, Japan.
Sakurai
H
H
Hasegawa
M
M
Kanuma
T
T
Segawa
A
A
Nakano
T
T
D000368:Aged; D001707:Biopsy, Needle; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009367:Neoplasm Staging; D011877:Radionuclide Imaging; D018714:Radiotherapy, Adjuvant; D012208:Rhabdomyosarcoma / Q000175:diagnosis* / Q000628:therapy*; D018570:Risk Assessment; D014057:Tomography, X-Ray Computed; D014625:Vaginal Neoplasms / Q000175:diagnosis* / Q000628:therapy*