[A case of infant with paroxysmal downgaze].
We reported a girl showing paroxysmal downgaze as the only manifestation of neurological abnormality. The movement was first noted at the age of 75 postnatal days, increased in frequency gradually to 10 weeks, and decreasing gradually, and disappeared at 35 weeks. The eye movements comprised first rapid downward and floating and rapid upward to primary position. The phenomenon was only provoked by looking at her own finger in front of her at a distance of 5 cm, and looked like a overshoot of vertical saccade. The suppression of the saccade neurons in the superior colliculus by inhibitory systems from the frontal association cortex through the direct pathway of the basal ganglia was also immature in the baby.
Department of Pediatrics, National Sanatorium Toyama Hospital, Toyama. ntaki510@toyama.hosp.go.jp
Noboru
N
Takizawa
Seizo
S
Kyotani
D005260:Female; D005385:Fingers; D005625:Frontal Lobe / Q000503:physiopathology*; D006801:Humans; D007223:Infant; D009474:Neurons / Q000502:physiology; D015835:Ocular Motility Disorders / Q000503:physiopathology*; D012438:Saccades / Q000502:physiology*; D013477:Superior Colliculi / Q000502:physiology / Q000503:physiopathology