The Gly1057Asp polymorphism in IRS-2 interacts with obesity to affect beta cell function.
Stefan
N
N
Fritsche
A
A
Machicao
F
F
Tschritter
O
O
Häring
H U
HU
Stumvoll
M
M
Stumvogel
M
M
D001823:Body Composition / Q000502:physiology; D002096:C-Peptide / Q000378:metabolism; D006801:Humans; D055504:Insulin Receptor Substrate Proteins; D047908:Intracellular Signaling Peptides and Proteins; D007515:Islets of Langerhans / Q000503:physiopathology*; D009765:Obesity / Q000235:genetics* / Q000503:physiopathology*; D010641:Phenotype; D010750:Phosphoproteins / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*
D002096:C-Peptide; C526297:IRS2 protein, human; D055504:Insulin Receptor Substrate Proteins; D047908:Intracellular Signaling Peptides and Proteins; D010750:Phosphoproteins