Fatal, complete splenic infarction and hepatic infection due to disseminated Trichosporon beigelii infection: CT findings.
We report on a 56-year-old woman with acute lymphocytic leukemia who presented with right upper quadrant pain, fever, nausea, and vomiting. Laboratory studies confirmed fungemia with Trichosporum beigelii, and contrast-enhanced computed tomography of the abdomen demonstrated numerous low-attenuation liver lesions and a hypodense spleen with capsular enhancement suggestive of complete splenic infarction. Subsequent splenectomy confirmed that the spleen was completely infarcted and infiltrated with Trichosporum. The patient had a difficult postoperative course and died despite aggressive antifungal therapy.
Division of Abdominal Imaging and Intervention, Department of Radiology, Brigham & Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
S G
SG
Viscomi
K J
KJ
Mortelé
V
V
Cantisani
J
J
Glickman
S G
SG
Silverman
D000935:Antifungal Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003287:Contrast Media; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D009181:Mycoses / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy; D009894:Opportunistic Infections / Q000000981:diagnostic imaging* / Q000628:therapy; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D013156:Splenectomy; D014057:Tomography, X-Ray Computed; D014250:Trichosporon
D000935:Antifungal Agents; D003287:Contrast Media