Paroxysmal dysarthria and ataxia after midbrain infarction.
The authors describe a patient who showed paroxysmal dysarthria and right-limb ataxia after midbrain infarction. SPECT imaging showed marked hypoperfusion in the left parietal lobe while the patient was having frequent paroxysmal attacks. After treatment with phenytoin, the symptoms and hypoperfusion in SPECT imaging improved. The authors conclude that dysfunction of the cerebellothalamocortical pathway after midbrain infarction may cause paroxysmal dysarthria and ataxia.
Department of Neurology, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawaharacho, Sakyoku, Kyoto 606-8507, Japan. matsuim@kuhp.kyoto-u.ac.jp
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M
Matsui
H
H
Tomimoto
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K
Sano
K
K
Hashikawa
H
H
Fukuyama
H
H
Shibasaki
D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D002531:Cerebellum / Q000503:physiopathology; D004172:Diplopia / Q000209:etiology; D004401:Dysarthria / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D020234:Gait Ataxia / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D009434:Neural Pathways / Q000503:physiopathology; D010296:Parietal Lobe / Q000098:blood supply / Q000000981:diagnostic imaging / Q000503:physiopathology*; D010672:Phenytoin / Q000627:therapeutic use; D012008:Recurrence; D012678:Sensation Disorders / Q000209:etiology; D013788:Thalamus / Q000503:physiopathology; D015899:Tomography, Emission-Computed, Single-Photon
D000925:Anticoagulants; D010672:Phenytoin; D001241:Aspirin