Cellular addresses; step one in creating a glycocode.
In this issue of Chemistry & Biology, a library screening approach reveals at least four types of enzymes that attach galactosamine to build cell surface mucin-type glycoproteins. A better molecular understanding of how these information-carrying oligosaccharides are created sets the stage for designing more selective inhibitors and potential therapeutics.
Pohl
Nicola
N
Department of Chemistry and the Plant Sciences Institute, Gilman Hall, Iowa State University, Ames, IA 50011, USA.
D004798:Enzymes / Q000378:metabolism*; D005688:Galactosamine / Q000378:metabolism
D004798:Enzymes; D005688:Galactosamine