Application of moderate hydrostatic pressure induces unit-cell changes in rhombohedral insulin.
2Co(2+)-insulin crystals were subjected to hydrostatic pressures of up to 30 bar in a nitrogen gas cell. Changes in the diffraction pattern occurred at pressures as low as 5 bar. Analysis with standard image-processing software showed unit-cell dimension changes resulting in reductions in volume of up to 2.6%.
Biophysics Department, School of Biomolecular Sciences, Liverpool John Moores University, England.
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J
Nicholson
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F
Körber
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S
Lambert