A case of post-partum borderline tuberculoid leprosy complicated by a median nerve abscess, peptic ulceration and rifampicin-induced haemolytic renal failure.
We report a case of borderline tuberculoid leprosy complicated by a median nerve abscess, acute renal failure secondary to rifampicin-induced haemolysis and duodenal ulceration secondary to steroid use. Rifampicin induced hameolysis is a rare and probably under-reported complication of leprosy multi-drug therapy. It should be considered when patients complain of flu-like symptoms after taking their monthly rifampicin.
Department of Dermatology, Kings College Hospital, Denmark Hill, London SE 5, UK. danadw@globalnet.co.uk
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S
Dawe
D N J
DN
Lockwood
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Creamer
D000038:Abscess / Q000150:complications*; D058186:Acute Kidney Injury / Q000139:chemically induced*; D000328:Adult; D005260:Female; D006461:Hemolysis; D006801:Humans; D007917:Leprostatic Agents / Q000009:adverse effects*; D015439:Leprosy, Borderline / Q000150:complications* / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008475:Median Nerve; D010437:Peptic Ulcer / Q000150:complications*; D012293:Rifampin / Q000009:adverse effects*
D007917:Leprostatic Agents; D012293:Rifampin