Remarkable increase in central Japan in 2001-2002 of Neisseria gonorrhoeae isolates with decreased susceptibility to penicillin, tetracycline, oral cephalosporins, and fluoroquinolones.
Four hundred sixty-two clinical isolates of Neisseria gonorrhoeae recovered from 1999 through 2002 in central Japan were examined for MICs of antimicrobial agents. The majority was sensitive to ceftriaxone and spectinomycin, but a remarkable increase in isolates with decreased susceptibility to penicillin, tetracycline, oral cephalosporins, and fluoroquinolones was observed from 2001 through 2002.
Ito
Masayasu
M
Department of Urology, Gifu University School of Medicine, Gifu City, Gifu, Japan.
Yasuda
Mitsuru
M
Yokoi
Shigeaki
S
Ito
Shin-ichi
S
Takahashi
Yoshito
Y
Ishihara
Satoshi
S
Maeda
Shin-ichi
S
Deguchi
Takashi
T
D018550:Cephalosporin Resistance; D024881:Drug Resistance, Bacterial; D024841:Fluoroquinolones / Q000494:pharmacology; D006069:Gonorrhea / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects*; D010403:Penicillin Resistance; D013753:Tetracycline Resistance
D024841:Fluoroquinolones