Myocardial delayed enhancement imaging using inversion recovery single-shot steady-state free precession: initial experience.
OBJECTIVE
To evaluate the feasibility of using an inversion recovery single-shot steady-state free precession (SS_SSFP) sequence for myocardial delayed enhancement (MDE) imaging, and to compare SS_SSFP with the conventional inversion recovery segmented fast gradient echo (IR_FGRE) technique.


METHODS
Ten subjects (four volunteers and six patients with suspected or known coronary disease) were included in this study. All subjects were scanned with both IR_FGRE and SS_SSFP sequences 15-25 minutes after gadopentetate dimeglumine injection. Overall image quality, signal-to-noise ratios (SNRs), and contrast-to-noise ratios (CNRs) between the two techniques were compared.


RESULTS
Compared to IR_FGRE, SS_SSFP exhibited adequate image quality (average scores = 3.8 for IR_FGRE and 3.9 for SS_SSFP) with much shorter acquisition time (14.4 seconds for IR_FGRE and 1.3 seconds for SS_SSFP). SS_SSFP images showed higher SNRs (P < 0.05) and less motion artifact from breathing. Enhanced myocardium was detected by both techniques in three patients, but the image sharpness is compromised in SS_SSFP images.


CONCLUSIONS
SS_SSFP provides adequate image quality compared to IR_FGRE, while requiring a much shorter acquisition time. It is feasible to use SS_SSFP as an alternative method for MDE imaging, especially in patients who have difficulty with holding their breath.
Li
Wei
W
MRI Research, Department of Radiology, Evanston Hospital and Northwestern University Feinberg School of Medicine, 2650 Ridge Avenue, Evanston, IL 60201, USA. lwei@enh.org
Li
Belinda S Y
BS
Polzin
Jason A
JA
Mai
Vu M
VM
Prasad
Pottumarthi V
PV
Edelman
Robert R
RR
D000368:Aged; D003327:Coronary Disease / Q000175:diagnosis*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology