Plan-sponsor savings and member experience with point-of-service prescription step therapy.
OBJECTIVE
To examine the effect of prescription step-therapy programs in terms of plan-sponsor savings and member experience at the point of service.


METHODS
Plan-sponsor savings were measured using a quasi-experimental, case-control design. Member experience with step therapy was measured using a self-administered mailed survey.


METHODS
A 20,000-member plan implemented 3 step therapy programs in September 2002: proton pump inhibitors, selective serotonin reuptake inhibitors, and nonsteroidal anti-inflammatory drugs. Pharmacy claims from September 1, 2001, through June 30, 2003, were examined to compare changes in per-member-per-month (PMPM) net cost between the intervention group and a random sample of members from commercial plans without the step therapy programs. A mailed, self-administered survey was sent to members with a step edit from September 1, 2002 to December 31, 2002.


RESULTS
The employer experienced a decrease of 0.83 dollars in net cost after implementing step therapy, while the comparison group had an upward trend of 0.10 dollars PMPM for these therapy classes. Member-reported outcomes indicated that approximately 30% of patients received a generic, 23% were granted a medical exception for the brand, 17% received no medication, and 16% paid the full retail price for the brand. If the pharmacist vs the patient contacted the physician, members were 8 times more likely to receive a medication covered by the health plan (OR, 8.10; 95% CI, 2.94-22.33 vs OR, 8.23; 95% CI, 3.11-21.93). Compared with those who received first-line therapy, those who paid out of pocket for the brand medication vs those who did not receive any medication were less likely to be satisfied with their pharmacy benefit (OR, 0.25; 95% CI, 0.08-0.80 vs OR, 0.12; 95% CI, 0.04-0.41).


CONCLUSIONS
Step therapy produces significant drug savings. However, there appear to be opportunities to further members' and providers' understanding of these programs.
Motheral
Brenda R
BR
Outcomes Research, Express Scripts. Inc, Maryland Heights, MO 63043, USA.
Henderson
Rochelle
R
Cox
Emily R
ER
D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D017046:Cost Savings; D003625:Data Collection; D011307:Drug Prescriptions; D005260:Female; D006264:Health Benefit Plans, Employee / Q000191:economics*; D006801:Humans; D008297:Male; D008875:Middle Aged