[Malignant tumours arising in extraovarian endometriosis: three case reports and review of the literature].
In its extraovarian form, co-existence of carcinoma and endometriosis is a sufficient argument used in favour of the malignant transformation of endometric lesions. Estrogen as well as the loss of 5q chromosome heterozygosity are considerate as initiators of that type of carcinogenesis. Endometrioid histological type is the most frequent and is revealed usually by abdominal pain. The incidence of carcinoma arising in endometriosis is about 0.8% and 5-year survival rate of pelvic endometrioid form is about a 100% after surgery and radiotherapy.
Benoit
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L
Service de chirurgie, centre G.-F.-Leclerc, 1 rue du Pr-Marion, BP 77980, 21079 Dijon cedex, France. martine.brisebard@chu-dijon.fr
Arnould
L
L
Margarot
A
A
Franceschini
C
C
Collin
F
F
Fraisse
J
J
Cuisenier
J
J
D000008:Abdominal Neoplasms / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D002277:Carcinoma / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology* / Q000601:surgery; D004715:Endometriosis / Q000150:complications*; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D011379:Prognosis
D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil