Structural analysis of selected characteristic flavones by electrospray tandem mass spectrometry.
Seven structure analogical flavonoid aglycones have been analyzed using electrospray ionization tandem mass spectrometry (ESI-MSn) in the negative-ion mode. The spectra obtained ESI-MSn allowed us to propose plausible schemes for their fragmentation mechanism. By analyzing the product ions spectra of deprotonated molecule ions [M-H](-), some neutral diagnostic losses and specific retro Diels-Alder fragments were obtained. By using all of these characteristic fragment ions we can specially differentiate the flavone isomer.
Laboratory of New Drug Research and Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, PR, China.
Wei
W
Wu
Zhiqiang
Z
Liu
Fengrui
F
Song
Shuying
S
Liu
D005419:Flavonoids / Q000032:analysis*; D007477:Ions; D008956:Models, Chemical; D010936:Plant Extracts; D012680:Sensitivity and Specificity; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*
D005419:Flavonoids; D007477:Ions; D010936:Plant Extracts