[Leydig cell tumor presenting as precocious pseudopuberty in a 4-year-old boy].
OBJECTIVE
To report one case of isosexual precocious pseudopuberty in a 4-year-old boy caused by an interstitial cell testicular tumor.


METHODS
Physical exam, blood tests, hormonal determinations, adrenal suppression tests, bone age, orchiectomy and pathologic study of the specimen were performed.


RESULTS
Physical examination showed a boy with muscle development, acne; body, sexual and face hair corresponding to an older boy; with increased volume of the left testicle and infantile contralateral testicle. Urinary 17-ketosteroids were elevated and did not decrease after dexametasone. Bone age corresponded to an 11-year-old standard. Pathologic study showed an interstitial cell tumor. Puberty changes disappeared after orchiectomy.


CONCLUSIONS
This diagnosis should be taken into consideration in every case of accelerated sexual development in a boy with testicular tumor and without maturation of the contralateral testicle.
Alonso Domínguez
Francisco Javier
FJ
Hospital Comandante Manuel Fajardo, Ciudad de la Habana, Cuba. falonso@manfa.sld.cu
Osorio Acosta
Vicente Angel
VA
D002675:Child, Preschool; D006801:Humans; D007984:Leydig Cell Tumor / Q000150:complications* / Q000601:surgery; D008297:Male; D011629:Puberty, Precocious / Q000209:etiology*; D013736:Testicular Neoplasms / Q000150:complications* / Q000601:surgery