Enhanced calcium absorption in the small intestine by a phytate-removed deamidated soybean globulin preparation.
Soybean globulins were deamidated after removing phytate using ion-exchange resins, and then hydrolyzed by digestive enzymes. The phytate-removed deamidated soybean globulins (PrDS) retained high calcium-binding ability even after the hydrolysis by digestive enzymes. PrDS and its hydrolysates enhanced calcium absorption from the small intestine when injected into the small intestine together with a calcium solution.
Kumagai
Hitomi
H
Department of Agricultural and Biological Chemistry, Nihon University, 1866 Kameino, Fujisawa-shi, Kanagawa 252-8510, Japan. kumagai@brs.nihon-u.ac.jp
Koizumi
Atsushi
A
Suda
Akihiro
A
Sato
Noriko
N
Sakurai
Hidetoshi
H
Kumagai
Hitoshi
H
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002918:Chymotrypsin / Q000378:metabolism; D005765:Gastrointestinal Agents / Q000378:metabolism; D005916:Globulins / Q000378:metabolism*; D007082:Ileum / Q000378:metabolism*; D066298:In Vitro Techniques; D007408:Intestinal Absorption; D008297:Male; D010434:Pepsin A / Q000378:metabolism; D010833:Phytic Acid / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D030262:Soybean Proteins / Q000378:metabolism*; D014357:Trypsin / Q000378:metabolism
D005765:Gastrointestinal Agents; D005916:Globulins; D030262:Soybean Proteins; D010833:Phytic Acid; D002918:Chymotrypsin; D014357:Trypsin; D010434:Pepsin A; D002118:Calcium