Enantioselective synthesis of the dioxabicyclo[3.2.1]octane core of the zaragozic acids via intramolecular Wacker-type cyclisation reactions.
Wacker-type cyclisation reactions provide an effective entry into the dioxabicyclo[3.2.1]octane core of the zaragozic acid analogues.
Perlmutter
Patrick
P
School of Chemistry, Monash University, PO Box 23, 3800, Australia. Patrick.Perlmutter@sci.monash.edu.au
Selajerern
Walailak
W
Vounatsos
Filisaty
F
D000935:Antifungal Agents / Q000138:chemical synthesis*; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis*; D003500:Cyclization; D013186:Farnesyl-Diphosphate Farnesyltransferase / Q000037:antagonists & inhibitors; D015394:Molecular Structure; D009795:Octanes / Q000138:chemical synthesis*; D013237:Stereoisomerism
D000935:Antifungal Agents; D019086:Bridged Bicyclo Compounds, Heterocyclic; D009795:Octanes; C079090:zaragozic acid C; D013186:Farnesyl-Diphosphate Farnesyltransferase