Concomitant cavernous hemangioma and venous angioma of the orbit.
BACKGROUND
An unusual case of cavernous hemangioma coexisting with venous angioma in the ipsilateral orbit is described.


METHODS
A 67-year-old woman had a mass in the lower eyelid of her right eye and proptosis. Imaging examinations showed two masses connected to each other in the extraconal space of the right orbit.


METHODS
Anterior orbitotomy was performed to remove the tumors. Histopathological evaluation of the anteriorly located tumor revealed cavernous hemangioma. The posteriorly located tumor was found to be a venous angioma. Endothelial cells in both tumors showed positive immunostaining for factor VIII-related antigen and smooth muscle actin. Immunoreactivity of smooth muscle actin was more prominent in the interstitium of the posteriorly located tumor.


CONCLUSIONS
Coexistence of cavernous hemangioma and venous angioma in the same area suggests that they are a continuum and of the same origin.
Kodama
Tatsuo
T
Department of Ophthalmology, Shimane University School of Medicine, Izumo, Japan. fifa2002@med.shimane-u.ac.jp
Tane
Nobuhiro
N
Ohira
Akihiro
A
Matsuoka
Yotaro
Y
Maruyama
Riruke
R
D000199:Actins / Q000378:metabolism; D000368:Aged; D004730:Endothelium, Vascular / Q000378:metabolism; D005260:Female; D006391:Hemangioma / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D006392:Hemangioma, Cavernous / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D009918:Orbital Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014680:Veins; D014841:von Willebrand Factor / Q000378:metabolism
D000199:Actins; D014841:von Willebrand Factor