Molecular epidemiology of Enterobacteriaceae isolates producing extended-spectrum beta-lactamases in a French hospital.
In 2002, 80 isolates of Enterobacteriaceae producing extended-spectrum beta-lactamases (ESBLs) were collected from infected patients in our hospital. Enterobacter aerogenes was the most common bacterium isolated from all specimens (36.5%). The ESBLs were predominantly (90%) TEM derivatives (TEM-24, TEM-3). Pulsed-field gel electrophoresis highlighted that E. aerogenes, Klebsiella pneumoniae, and Citrobacter koseri had a clonal propagation.
Laboratoire Universitaire d'Antibiologie, Faculté de Médecine, Ave. Kennedy, 30900 Nîmes, France. albert.sotto@chu-nimes.fr
Jean-Philippe
JP
Lavigne
Nicole
N
Bouziges
Catherine
C
Chanal
Aba
A
Mahamat
Sylvie
S
Michaux-Charachon
Albert
A
Sotto
D004755:Enterobacteriaceae / Q000145:classification / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections / Q000453:epidemiology*; D005602:France / Q000453:epidemiology; D006801:Humans; D007297:Inpatients / Q000706:statistics & numerical data; D017720:Molecular Epidemiology / Q000379:methods; D010802:Phylogeny; D001618:beta-Lactamases / Q000378:metabolism*
D001618:beta-Lactamases