Mucositis and airway obstruction in a pediatric patient.
Pediatric patients undergoing induction regimens of chemotherapy may require intubation and mechanical ventilation either for respiratory failure or airway compromise as a complication of their therapy. We describe a case of difficult airway management resulting from pseudomembrane formation in a 16-yr-old girl. The patient was undergoing induction chemotherapy for stage IV rhabdomyosarcoma and developed severe mucositis that led to progressive airway obstruction.
Department of Anesthesiology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire.
Kathleen H
KH
Chaimberg
Joseph P
JP
Cravero
D000293:Adolescent; D000402:Airway Obstruction / Q000209:etiology* / Q000473:pathology; D000903:Antibiotics, Antineoplastic; D018906:Antineoplastic Agents, Alkylating; D000972:Antineoplastic Agents, Phytogenic; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects; D003520:Cyclophosphamide; D003609:Dactinomycin; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal; D009092:Mucous Membrane / Q000473:pathology*; D012208:Rhabdomyosarcoma / Q000150:complications / Q000188:drug therapy; D014750:Vincristine
D000903:Antibiotics, Antineoplastic; D018906:Antineoplastic Agents, Alkylating; D000972:Antineoplastic Agents, Phytogenic; D003609:Dactinomycin; D014750:Vincristine; D003520:Cyclophosphamide