Cryptococcal sepsis diagnosed by bone marrow examination.
Disseminated cryptococcal disease is often associated with immunodeficient states. The diagnosis is usually made using standard antigen tests on serum and cerebrospinal fluid in patients with known immunodeficiency. Often, blood and cerebrospinal fluid cultures also yield Cryptococcus neoformans. The authors describe a child whose diagnosis remained elusive until a bone marrow aspiration, performed as part of an evaluation for suspected neoplasm, revealed the offending organism.
Abdul-Rahman
Omar A
OA
Department of Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA. oabdul_rahman@hotmail.com
Gay
Hannah
H
Caldwell
Elizabeth
E
Megason
Gail C
GC
D001853:Bone Marrow / Q000382:microbiology*; D001856:Bone Marrow Examination; D002648:Child; D003453:Cryptococcosis / Q000175:diagnosis* / Q000382:microbiology; D003455:Cryptococcus neoformans / Q000302:isolation & purification*; D016469:Fungemia / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D008297:Male