The role of IL-5 in the immune responses to nematodes in rodents.
In this review, Masataka Korenoga and Isoo Toda discuss the role of interleukin 5 (IL-5) in immune responses caused by parasitic infections. Recent studies have shown that eosinophilia in parasitic infections is dependent on IL-5. Although eosinophils have been thought to be potent effector cells (from results of experiments, in vitro), their role in protective immunity to parasites is controversial.
Department of Oncology, Kumamoto University Medical School, 2-2-1 Honjo, Kumamoto 860, Japan.
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Tada