Telomerase RNA: a flexible RNA scaffold for telomerase biosynthesis.
Determination of the structure of the yeast telomerase RNA component TLC1 has been hampered by its large size and high rate of evolutionary divergence. But detailed phylogenetic comparisons have now revealed the unusually flexible and modular architecture of this important RNA molecule.
Lustig
Arthur J
AJ
Department of Biochemistry, Tulane University Heath Sciences Center, New Orleans, Louisiana 70112, USA. alustig@tulane.edu
D004268:DNA-Binding Proteins; D009690:Nucleic Acid Conformation; D010802:Phylogeny; D012313:RNA / Q000235:genetics / Q000378:metabolism* / Q000502:physiology*; D012440:Saccharomyces; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism; D013045:Species Specificity; D019098:Telomerase / Q000096:biosynthesis* / Q000235:genetics / Q000378:metabolism* / Q000502:physiology*
D004268:DNA-Binding Proteins; D029701:Saccharomyces cerevisiae Proteins; C422952:telomerase RNA; D012313:RNA; C099024:EST1 protein, S cerevisiae; D019098:Telomerase