Epithelioid haemangioendothelioma of the parotid salivary gland: a case report.
Haemangioendothelioma is a vascular tumour characterised by the proliferation of endothelial cells with an epithelioid appearance. The behaviour of this neoplasm is intermediate between haemangioma and angiosarcoma. It may be localised in a wide range of sites, with a preference for soft and bone tissue. It is only rarely localised in the head and neck and even more rarely in the salivary glands. We describe a case of haemangioendothelioma in a 28-year-old man that originated in the retroneural region of the parotid gland, compressing the gland tissue and posteriorly infiltrating the muscular plane. A total parotidectomy surgical operation including the removal of lymph nodes in the region was performed followed by radiotherapy. An immunohistochemical investigation, carried out using the oxidase-antiperoxidase method, indicated that the neoplastic elements of the marker of the endothelial cells CD34 were positive for vimentine and for muscle-specific actin, showing a moderate proliferative action of the cellular elements with MIB-1 positivity estimated at around 6%. The peculiarity of the case we describe resides in the rarity of the haemangioendothelioma localisation in the parotid gland.
Division of General Surgery, Department of Surgical Science, 3rd Training Program in General Surgery, La Sapienza University of Rome.
Laura
L
Falvo
Antonella
A
Marzullo
Antonio
A
Catania
Salvatore
S
Sorrenti
Alberto
A
Berni
Antonio Paniccia
AP
Bonifazi
Matteo
M
De Stefano
Enrico
E
De Antoni
D000328:Adult; D018323:Hemangioendothelioma, Epithelioid / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008297:Male; D010307:Parotid Neoplasms / Q000473:pathology* / Q000601:surgery*