A complete and durable clinical response to high-dose dexamethasone in a patient with scleromyxedema.
We report a case of a patient with scleromyxedema limited to the skin with an associated IgG lambda monoclonal protein treated successfully with high-dose dexamethasone. We encourage the continued investigation of this complex relationship between the clinical presentation of scleromyxedema and its frequently associated paraproteinemia.
Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Keren B
KB
Horn
Meyer A
MA
Horn
James
J
Swan
Seema
S
Singhal
Joan
J
Guitart
D001706:Biopsy; D003907:Dexamethasone / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D008875:Middle Aged; D045743:Scleroderma, Diffuse / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D012867:Skin / Q000473:pathology
D003907:Dexamethasone