The effect of cyproterone acetate on the antler cycle in red deer (Cervus elaphus L.).
The aim of the study was to test the effect of antiandrogen, cyproterone acetate (CA) on the antler cycle in the red deer (Cervus elaphus). CA was administered to three adult red deer stags (Edward, Fuks and Gacek) in weekly intervals. Edward and Fuks were given 600 mg + 600 mg of CA, whereas Gacek was given 600 mg + 300 mg. CA was injected during the hard antler phase: in mid-October (Edward), at the end of November (Fuks) and at the end of January (Gacek). CA caused the antler casting 17 to 22 days after the first injection. In all stags, the casting of antlers was followed by a period of intensive growth of new antlers. Edward was given CA at the end of October. This treatment was responsible for occurrence of the two antler cycles in the year of the experiment. When CA was administered during the middle of the hard antler phase an additional short antler cycle occurs followed by new antler growth. CA treatment in the later part of hard antler phase may cause a prolonged antler cycle.
Jaczewski
Zbigniew
Z
Polish Academy of Science, Institute of Genetics and Animal Breeding, Jastrzebiec.
Gizejewski
Zygmunt
Z
Bartecki
Ryszard
R
D000726:Androgen Antagonists / Q000494:pharmacology*; D000818:Animals; D000999:Antlers / Q000187:drug effects / Q000502:physiology*; D017373:Cyproterone Acetate / Q000494:pharmacology*; D003670:Deer / Q000502:physiology*; D008297:Male; D012621:Seasons
D000726:Androgen Antagonists; D017373:Cyproterone Acetate