Metastatic follicular dendritic cell sarcoma of the stomach: a case report and review of the literature.
Follicular dendritic cell (FDC) sarcomas are rare tumours, typically seen in lymph nodes. However, in about one third of the reported cases, a FDC sarcoma presents as an extranodal mass. Involvement of the gastrointestinal tract is extremely rare, and only 3 cases have been described to date. We report on a 40-year-old female patient with a follicular dendritic cell sarcoma located in the stomach and the presence of a metastasis in the liver at the time of diagnosis. Severe asthenia, nausea, back pain and loss of weight were the presenting symptoms. A CT scan of the abdomen and an upper gastrointestinal endoscopy revealed a tumour mass in the stomach. The diagnosis of a FDC sarcoma was made on histological and immunohistochemical findings. We report the second case of a FDC sarcoma presenting in the stomach. Due to its rarity, a FDC sarcoma seldom enters the differential diagnosis of spindle cells neoplasms of the gastrointestinal tract. Complete surgical resection is the treatment of choice for FDC sarcoma.
Geerts
A
A
Department of Gastroenterology, University Hospital Ghent, Ghent, Belgium. anja.geerts@pandora.be
Lagae
E
E
Dhaene
K
K
Peeters
M
M
Waeytens
A
A
Demetter
P
P
Cuvelier
C
C
Defreyne
L
L
De Vos
M
M
Pattyn
P
P
D000328:Adult; D020566:Dendritic Cells, Follicular / Q000473:pathology*; D005260:Female; D005743:Gastrectomy / Q000379:methods; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery; D012509:Sarcoma / Q000556:secondary* / Q000601:surgery; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome