[Clinical characteristics of cerebral infarction in China and Japan].
In order to elucidate the clinical characteristics of cerebral infarction in a northeastern district of China, 1,353 patients with first-ever cerebral infarction in Shenyang, China, were compared with 2,929 patients registered in Japan. Using the identical database (Japan Standard Stroke Registry Study), we prospectively collected clinical data on acute ischemic stroke patients who were admitted to two main hospitals in Shenyang, China, and 50 hospitals in Japan. The mean age was 67.3 years in China and 71.3 years in Japan. Of the patients in China, 78% were classified as atherothrombotic infarction, 18% as lacunae, and 1% as cardioembolism. By contrast, 30% of the patients in Japan were classified as atherothrombotic infarction, 32% as lacunae, and 31% as cardioembolism. Regarding the risk factors, the incidence of hypertension was 76% in China and 62% in Japan. Diabetes mellitus was 10% in China and 26% in Japan. Hyperlipidemia was 10% in China and 22% in Japan. Atrial fibrillation was 3% in China and 21% in Japan. As the diagnostic criteria for hyperlipidemia differed, we could not compare this risk factor between the two countries statistically; however, cardioembolism, lacunae, and atrial fibrillation were significantly less common in China than in Japan. Our data suggest that hypertension is an important risk factor for ischemic stroke, and the incidence of cardioembolism and atrial fibrillation is very low in Shenyang, China.
Department of Neurology, Hematology, Rheumatology, Shimane University School of Medicine.
Lihua
L
Wu
Kazuo
K
Takahashi
Shotai
S
Kobayashi
Guoping
G
Tian
Lichun
L
Song
Ryukichi
R
Matui
Shuhei
S
Yamaguchi
D000367:Age Factors; D000368:Aged; D002544:Cerebral Infarction / Q000453:epidemiology* / Q000209:etiology; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012042:Registries; D012737:Sex Factors; D020521:Stroke / Q000453:epidemiology