Effects of secretory products of activated neutrophils on morphological composition and functional activity of peritoneal exudation cells during inflammation of staphylococcal origin.
Substance A5 isolated from supernatants of activated neutrophils from donors significantly increases the percentage of neutrophils and macrophages in the peritoneal exudation of mice on days 3 and 7 of staphylococcal inflammation and stimulates functional activity (lysosomal, phagocytic, and NBT-reducing) of these cells, reduced as a result of inflammation, on days 3, 7, and 14 of the inflammatory process.
Institute of Immunology, Chelyabinsk State Medical Academy. kanc@vita.chel.su
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Tretyakova
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Dolgushin
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Zurochka
D000818:Animals; D001202:Ascitic Fluid / Q000473:pathology* / Q000503:physiopathology; D007249:Inflammation / Q000473:pathology* / Q000503:physiopathology*; D008247:Lysosomes / Q000502:physiology; D008264:Macrophages / Q000473:pathology; D051379:Mice; D008808:Mice, Inbred CBA; D018375:Neutrophil Activation; D009504:Neutrophils / Q000378:metabolism* / Q000473:pathology / Q000502:physiology; D009580:Nitroblue Tetrazolium / Q000378:metabolism; D010084:Oxidation-Reduction; D010587:Phagocytosis; D013203:Staphylococcal Infections / Q000473:pathology* / Q000503:physiopathology*
D009580:Nitroblue Tetrazolium