[Progress in Notch signaling].
Notch signaling plays a vital role in cell fate decisions in both invertebrate and vertebrate development. Signals exchanged between neighboring cells through the Notch receptor amplify and consolidate molecular differences, which eventually dictate cell fates. In this review, the details of notch signaling will be discussed, with a focus on Lin/Notch repeats (CSL) independent modes.
Lu
Zhuo-Zhuang
ZZ
Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850.
Wang
Li-Sheng
LS
Wu
Chu-Tse
CT
D002352:Carrier Proteins / Q000502:physiology*; D002450:Cell Communication; D002453:Cell Cycle / Q000502:physiology*; D002455:Cell Division; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D006801:Humans; D008565:Membrane Proteins / Q000502:physiology*; D011499:Protein Processing, Post-Translational; D051880:Receptors, Notch; D015398:Signal Transduction / Q000502:physiology*
D002352:Carrier Proteins; D004268:DNA-Binding Proteins; D008565:Membrane Proteins; D051880:Receptors, Notch; C409218:deltex protein, vertebrate