[Albumin dialysis MARS (Molecular Adsorbent Recirculating System) as a bridge for liver transplantation in acute liver failure. Report of three cases].
The most successful therapy for acute liver failure is liver transplantation. However, due to the low number of donors, organ support therapies need to be used as a bridge to liver transplantation. Molecular Adsorbents Recirculating System (MARS) is a dialysis treatment that uses a recirculating dialysate containing albumin. This allows the removal of both hydrosoluble and albumin-related substances. This system improves hepatic encephalopathy, renal dysfunction and some clinical parameters in acute liver failure, but there is no clear decrease in mortality. We report three women aged 23, 21 and 61 years, that were subjected to liver transplantation, in whom this therapy was successfully used.
Contreras
Jorge
J
Sección de Gastroenterología, Departamento de Medicina, Hospital Clínico Universidad de Chile, Santiago. jcontreras@ns.hospital.uchile.cl
Poniachik
Jaime
J
Oksenberg
Dan
D
Cortés
Claudia
C
Valera
José Miguel
JM
Cotera
Alejandro
A
Pacheco
Alejandro
A
Segovia
Erico
E
Sanhueza
María Eugenia
ME
Boltansky
Andrés
A
Rojas
Jorge
J
Guerrero
Julia
J
Díaz
Juan Carlos
JC
D058186:Acute Kidney Injury / Q000628:therapy; D000328:Adult; D000418:Albumins / Q000627:therapeutic use*; D000641:Ammonia / Q000097:blood; D001663:Bilirubin / Q000097:blood; D015415:Biomarkers / Q000097:blood; D001806:Blood Urea Nitrogen; D003404:Creatinine / Q000097:blood; D005260:Female; D006501:Hepatic Encephalopathy / Q000628:therapy*; D006801:Humans; D016031:Liver Transplantation; D008875:Middle Aged; D006435:Renal Dialysis / Q000379:methods; D016060:Sorption Detoxification / Q000379:methods*
D000418:Albumins; D015415:Biomarkers; D000641:Ammonia; D003404:Creatinine; D001663:Bilirubin