Crystals of ligand-free bovine neurophysin II.
A modified neurophysin, des 1-6 bovine neurophysin II, has been crystallized in the absence of bound hormone or hormone analogue. These crystals represent the first crystals of ligand-free neurophysin, and are essential for understanding neurophysin-hormone recognition as well as hormone-induced neurophysin dimerization. The crystals diffract to beyond 1.8 A resolution, belong to space group P3(1)21 (or P3(2)21) with a = 48.86, c = 78.61 A, and contain one molecule per asymmetric unit.
Department of Biochemistry and Molecular Biology, University of Georgia, Athens 30602, USA.
C K
CK
Wu
J P
JP
Rose
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C
Zheng
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Breslow
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Wang