Consensus opinion from the antibody working group on the diagnosis, reporting, and risk assessment for antibody-mediated rejection and desensitization protocols.
During the past few decades, much of the experimental and clinical effort in solid-organ transplantation has been directed toward ameliorating or abrogating T-cell-mediated responses. As a result, universally understood and accepted nomenclature and diagnostic criteria have evolved. Humoral immunity in transplantation has yet to undergo a similar renaissance. Readers of transplant journals regularly find it difficult and often impossible to interpret data on the diagnosis and management of antibody-mediated rejection. The Antibody Working Group was assembled in an attempt to provide guidelines for the standardization of nomenclature, diagnostic criteria, reporting, antibody profiling, and risk assessment.
Montgomery
Robert A
RA
Department of Surgery, Division of Transplantation, Johns Hopkins University School of Medicine, Ross 765/720 Rutland Avenue, Baltimore, MD 21205, USA.
Hardy
Mark A
MA
Jordan
Stanley C
SC
Racusen
Lorraine C
LC
Ratner
Lloyd E
LE
Tyan
Dolly B
DB
Zachary
Andrea A
AA
D006084:Graft Rejection / Q000276:immunology* / Q000517:prevention & control*; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods*; D007518:Isoantibodies / Q000276:immunology*; D018448:Models, Immunological; D013601:T-Lymphocytes / Q000276:immunology*; D019172:Transplantation Conditioning / Q000379:methods
D007518:Isoantibodies