Induction of imatinib metabolism by hypericum perforatum.
Smith
Patrick F
PF
Bullock
Julie M
JM
Booker
Brent M
BM
Haas
Curtis E
CE
Berenson
Charles S
CS
Jusko
William J
WJ
D000970:Antineoplastic Agents / Q000378:metabolism / Q000493:pharmacokinetics; D001549:Benzamides; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics; D004347:Drug Interactions; D005786:Gene Expression Regulation; D006801:Humans; D020902:Hypericum; D000068877:Imatinib Mesylate; D010879:Piperazines / Q000378:metabolism / Q000493:pharmacokinetics*; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D011743:Pyrimidines / Q000378:metabolism / Q000493:pharmacokinetics*
D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D010936:Plant Extracts; D011743:Pyrimidines; D000068877:Imatinib Mesylate; D003577:Cytochrome P-450 Enzyme System; C104464:CYP3A protein, human; D051544:Cytochrome P-450 CYP3A