Morphology of reparative regeneration in organs and tissues during treatment with new generation Sulfacrylate.
We studied morphogenesis of reparative processes in parenchymatous and hollow organs after surgery with the use of Sulfacrylate glue composition characterized by good adhesive and bactericidal properties. The glue rapidly and effectively arrested parenchymatous bleeding, reduced the volume of necrotic tissue, and promoted wound healing without suppuration. Cicatrix was completely formed 1 month after surgery and the glue completely resorbed at this term. The bioglue reliably connected and hermetically sealed sutures when used for gluing intestinal loops and for creation of intestinal anastomoses. The use of biological glue promoted the formation of elastic fibrous tissue not distorting the intestinal lumen.
Research Center of Clinical and Experimental Medicine, Novosibirsk. pathol@cyber.am.nsc.ru
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Marchenko
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Shkurupii
D000180:Acrylic Resins / Q000494:pharmacology*; D000269:Adhesives / Q000494:pharmacology*; D000818:Animals; D002415:Cats; D007668:Kidney / Q000293:injuries / Q000502:physiology / Q000601:surgery; D008099:Liver / Q000293:injuries / Q000502:physiology / Q000601:surgery; D008115:Liver Regeneration / Q000187:drug effects; D011817:Rabbits; D051381:Rats; D012038:Regeneration / Q000187:drug effects*; D013154:Spleen / Q000293:injuries / Q000502:physiology / Q000601:surgery; D013997:Time Factors
D000180:Acrylic Resins; D000269:Adhesives; C036516:sulfacrylate