[Progress in Notch signaling].
Notch signaling plays a vital role in cell fate decisions in both invertebrate and vertebrate development. Signals exchanged between neighboring cells through the Notch receptor amplify and consolidate molecular differences, which eventually dictate cell fates. In this review, the details of notch signaling will be discussed, with a focus on Lin/Notch repeats (CSL) independent modes.
Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850.
Zhuo-Zhuang
ZZ
Lu
Li-Sheng
LS
Wang
Chu-Tse
CT
Wu
D002352:Carrier Proteins / Q000502:physiology*; D002450:Cell Communication; D002453:Cell Cycle / Q000502:physiology*; D002455:Cell Division; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D006801:Humans; D008565:Membrane Proteins / Q000502:physiology*; D011499:Protein Processing, Post-Translational; D051880:Receptors, Notch; D015398:Signal Transduction / Q000502:physiology*
D002352:Carrier Proteins; D004268:DNA-Binding Proteins; D008565:Membrane Proteins; D051880:Receptors, Notch; C409218:deltex protein, vertebrate