Depigmentation--a rare side effect to intra-articular glucocorticoid treatment.
Intra-articular glucocorticoid injections are often used in patients with rheumatoid arthritis, either as bridging therapy or in periods with increased disease activity. We present a case of local skin depigmentation that occurred at the site of injection in a dark-skinned patient. Depigmentation is a rare complication of such therapy but may have important implications for dark-skinned patients.
Department of Rheumatology, Copenhagen University Hospital at Hvidovre, Denmark.
Cornelia
C
Rogojan
Merete Lund
ML
Hetland
D001623:Betamethasone / Q000008:administration & dosage / Q000009:adverse effects*; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007270:Injections, Intra-Articular; D008297:Male; D008875:Middle Aged; D010859:Pigmentation Disorders / Q000139:chemically induced* / Q000473:pathology; D012075:Remission, Spontaneous; D012880:Skin Pigmentation / Q000187:drug effects*
D005938:Glucocorticoids; D001623:Betamethasone