Association between injection practices and duration of injection among recently initiated injection drug users.
BACKGROUND
Earlier studies suggest higher infection risk among recently initiated injection drug users (IDUs) than more experienced users. Whether IDUs' risky injection practices rise progressively with duration of injection or frequency of practices is higher near initiation and then taper remains an open question.


METHODS
Recently initiated IDUs were street recruited and interviewed between 1997 and 1999 as part of a multisite cohort study in five US urban cities. Recent risky injection practices (injecting with others and injecting on average more now) were examined across three cross-sections defined by duration of injection: 0-1 year, 2-3 years, and 4-6 years.


RESULTS
The IDU groups of <2 years duration (n = 691) and 2-3 years duration (n = 697) had higher odds than the 4-6 year group (n = 520) of reporting injecting with others (Odds Ratio, OR = 1.52, and OR = 1.47, respectively) and injecting on average more now (OR = 1.44 and OR = 1.44, respectively). The associations remained after multivariate adjustment for demographic variables.


CONCLUSIONS
These data on recently initiated IDUs suggest that risky injection practices were more frequent earlier than later within the first 6 years of initiation, emphasizing that outreach prevention needs to identify and intervene with IDUs early.
Center for Urban Epidemiological Studies, New York Academy of Medicine, New York City, NY 10029-5293, USA. meredith.buxton@ucsfmedctr.org
Meredith
M
Becker Buxton
David
D
Vlahov
Steffanie A
SA
Strathdee
Don C
DC
Des Jarlais
Edward V
EV
Morse
Lawrence
L
Ouellet
Peter
P
Kerndt
Richard S
RS
Garfein
D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D015331:Cohort Studies; D003141:Communicable Diseases / Q000453:epidemiology / Q000209:etiology / Q000821:virology; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D016017:Odds Ratio; D012307:Risk Factors; D015819:Substance Abuse, Intravenous / Q000150:complications / Q000453:epidemiology* / Q000821:virology; D013997:Time Factors