Adnexal torsion following gonadotropin-releasing hormone analog therapy: a case report.
Adnexal torsion may occur in girls and adolescents. Often it is associated with ovarian diseases resulting in ovarian enlargement. Adnexal torsion may involve the ovary, fallopian tube or both, and the main symptom is acute pelvic pain. An 8-year-old girl complaining of acute pelvic and abdominal pain, who was previously diagnosed with precocious puberty and who received treatment with a GnRH analog, is reported. Ultrasound demonstrated a normal-sized uterus and bilaterally enlarged ovaries with multiple internal cysts. At laparotomy, we found a complete torsion in the right adnexa. The histological examination revealed massive edema associated with multiple antral follicles and reduction of the follicular reserve.
Carvalho
Jesus Paula
JP
Pathology Division, Gynecologic Emergency Service, Hospital das Clínicas, Faculty of Medicine, University of São Paulo, São Paulo, SP, Brazil. carvalhojp@uol.com.br
Diegoli
Mara Solange
MS
Carvalho
Filomena Marino
FM
Diegoli
Carlos Alberto
CA
D000291:Adnexal Diseases / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D002648:Child; D005260:Female; D005300:Fertility Agents, Female / Q000009:adverse effects* / Q000627:therapeutic use; D005359:Fibrous Dysplasia, Polyostotic / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D016729:Leuprolide / Q000009:adverse effects* / Q000627:therapeutic use; D011629:Puberty, Precocious / Q000188:drug therapy*; D014102:Torsion Abnormality / Q000139:chemically induced / Q000473:pathology / Q000601:surgery
D005300:Fertility Agents, Female; D016729:Leuprolide