The effect of sevoflurane on rat liver mitochondrial respiration.
The effect of sevoflurane on rat liver mitochondrial respiration has been investigated with a Clark type oxygen electrode at 25 degrees C, pH 7.4. The higher susceptibility of NADH-linked substrate (glutamate) oxidation (with respect to succinate oxidation) to the damages by sevoflurane has been confirmed.
Department of Anesthesiology, St Marianna University, School of Medicine, Kawasaki, Japan.
H
H
Yokoyama
N
N
Kubota
T
T
Shibata
J
J
Nonaka
R
R
Matsuo
K
K
Takahashi