Rosetting.
Why do some individuals get severe falciparum malaria while others don't? Rosetting (the binding of uninfected erythrocytes to Plasmodium falciparum-infected erythrocytes), together with endothelial cytoadherence, has been shown to play a crucial role in the obstruction of the microvosculoture in P. falciparum malaria. Here, Mats Wahlgren, Victor Fernandez, Carin Scholonder and Johan Carlson review the literature surrounding rosetting.
Microbiology and Tumorbiology Center, Karolinska Institutet, Stockholm, Sweden.
M
M
Wahlgren
V
V
Fernandez
C
C
Scholander
J
J
Carlson