[Coagulation disorders and arterial thromboembolic events in non-small-cell lung cancer. A case report].
Certain coagulation disorders can occur in patients with cancer and thromboembolic complications are frequent. We report the case of a 53-Year-old patient with metastatic adenocarcinoma of the lung treated with chemotherapy who presented several cerebral arterial thromboembolic events leading to death a few weeks after the initial diagnosis of cancer. This case illustrates the important role of certain satellite disorders related to coagulation activation: non-bacterial thrombotic endocarditis, disseminated intravascular coagulation, anti-phospholipid antibody syndrome. The role of anticancer chemotherapy as a favoring factor for thromboembolic events is also emphasized in patients with non-small-cell lung cancer.
Service de Pneumologie, Hôpitaux Civils de Strasbourg, BP 426, 67091 Strasbourg Cedex.
A
A
Blanc
B
B
Mennecier
N
N
Lefebvre
J-L
JL
Pasquali
P
P
Fraisse
E
E
Weitzenblum
D000230:Adenocarcinoma / Q000150:complications* / Q000188:drug therapy; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications* / Q000188:drug therapy; D002539:Cerebral Arterial Diseases / Q000209:etiology*; D006801:Humans; D020766:Intracranial Embolism / Q000209:etiology*; D008175:Lung Neoplasms / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D013923:Thromboembolism / Q000209:etiology*
D000970:Antineoplastic Agents