Nucleic acids: vaccines of the future.
The recent successful immunization of experimental animals using nucleic acids has provided a revolutionary new approach in vaccinology. In this article, Gary Waine and Don McManus examine the potential of nucleic acid vaccines for their effectiveness not only against infectious and parasitic organisms exhibiting an intracellular phase during their life cycle, but also against parasitic helminths, whose life cycle stages are either predominantly or completely extracellular.
Waine
G J
GJ
Tropical Health Programme, Molecular Parasitology Unit, Queensland Institute of Medical Research, Brisbane, Australia. garyW@qimr.edu.au
McManus
D P
DP