Elicited repetitive daily blindness: a new familial disorder related to migraine and epilepsy.
The authors report a family affected by multiple daily episodes of transient visual loss, elicited repetitive daily blindness (ERDB); the onset was early in life, and the disease followed a benign course. ERDB is associated with childhood epilepsy and familial hemiplegic migraine, apparently segregating as a monogenic, autosomal dominant condition with variable expression. Genetic linkage to CACNA1A was excluded.
dominiquelefort@hotmail.com
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Le Fort
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Safran
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Picard
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Bouchardy
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Morris
D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D020757:Amaurosis Fugax / Q000209:etiology / Q000235:genetics*; D015220:Calcium Channels / Q000235:genetics; D002648:Child; D004244:Dizziness; D004828:Epilepsies, Partial / Q000235:genetics*; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D020325:Migraine with Aura / Q000235:genetics*; D010375:Pedigree; D010775:Photic Stimulation / Q000009:adverse effects; D011312:Pressure / Q000009:adverse effects; D013557:Switzerland; D020864:Calcium Channels, N-Type
D015220:Calcium Channels; C105656:CACNA1A protein, human; D020864:Calcium Channels, N-Type