[Efficacy of cytoflavin in spondylogenic radiculomyeloischemia].
The efficacy of cytoflavin in the treatment of 60 patients (39 women, 21 men, age 32-64 year) with spondylogenic cervical and lumbosacral radiculomyeloischemia due to degenerative dystrophic spinal lesions was studied in a randomized double-blind placebo controlled study according to GCP rules. During 10 days 40 patients received intravenous cytoflavin dropper injections once daily; 20 patients (control group) received 5% glucose solution as a placebo. Considerable improvement was observed in 70% patients with radiculomyeloischemia of cervical localization and in 65%--with radiculomyeloischemia of lumbosacral segments. In the control group, positive dynamics of neurologic symptoms was 25-30% lower. Cytoflavin significantly reduced cognitive disturbances, improved reparative processes both in the central and peripheral neurons, and may be recommended in ischemic neuronal spinal lesions.
A A
AA
Skoromets
V V
VV
Nikitina
D M
DM
Bykovitskiĭ
M L
ML
Pospelova
O G
OG
Sichkar'
A P
AP
Skoromets
T A
TA
Skoromets
A V
AV
Solonskiĭ
A A
AA
Timofeeva
D000328:Adult; D000975:Antioxidants / Q000627:therapeutic use*; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007511:Ischemia / Q000150:complications* / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009333:Neck; D012720:Severity of Illness Index; D013116:Spinal Cord / Q000098:blood supply*; D013167:Spondylitis, Ankylosing / Q000150:complications* / Q000188:drug therapy*
D000975:Antioxidants