Intrafamilial spread of the same clarithromycin-resistant Helicobacter pylori infection confirmed by molecular analysis.
Clarithromycin-resistant Helicobacter pylori (CRHP) is increasing worldwide, especially in children. We report a family case in which both the mother and child were infected with CRHP. DNA analysis revealed that all of the mother's and daughter's isolates were indistinguishable, suggesting that the same CRHP strain spread between the family members. The spread of CRHP within families may be increasing.
Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, 757 Ichibanchou, Asahimachidori, Niigata, Japan. tatsuoy@med.niigata-u.ac.jp
Ikue
I
Taneike
Keibun
K
Suzuki
Saori
S
Nakagawa
Tatsuo
T
Yamamoto
D000328:Adult; D000658:Amoxicillin / Q000627:therapeutic use*; D001944:Breath Tests; D002648:Child; D017291:Clarithromycin / Q000627:therapeutic use*; D018562:Disease Transmission, Infectious; D004359:Drug Therapy, Combination; D005260:Female; D005756:Gastritis / Q000382:microbiology; D016481:Helicobacter Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000635:transmission*; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D014508:Urea / Q000032:analysis
D000658:Amoxicillin; D014508:Urea; D017291:Clarithromycin