Head up tilt test in the diagnosis of neurocardiogenic syncope in childhood and adolescence.
BACKGROUND
Neurocardiogenic syncope (NCS) is a common paroxysmal disorder that is often misdiagnosed as a seizure disorder. Head up tilt test (HUTT) has been used to confirm this diagnosis. There is no data available of its use in children / adolescents from India.


OBJECTIVE
To study the usefulness of the HUTT in children and adolescents with suspected NCS.


METHODS
This was a part retrospective and later prospective study set in a tertiary child neurology outpatient department (OPD).


METHODS
Patients with a strong clinical suspicion of syncope were recruited for the study. Clinical and treatment details were either retrieved from the chart or prospectively recorded in later patients. The HUTT was then carried out at baseline and after provocation and the results correlated with the clinical diagnosis.


RESULTS
Eighteen children with a mean age of 10.8 years were studied. Eight had precipitating factors. Thirteen had premonitory symptoms. Pallor, temperature change, diaphoresis, headache, tonic / clonic movements, post-ictal confusion and peri-ictal headache were symptoms noticed. Sixteen had a positive HUTT. Seven were on long-term anti-epileptic drugs (AEDs). Two had epileptiform abnormalities on their electroencephalogram (EEG).


CONCLUSIONS
The diagnosis of syncope is often confused with epilepsy. Head up tilt test has a high sensitivity in the diagnosis of NCS in children / adolescents. It is fairly safe and easy to perform.
Department of Pediatrics and Neurology, P. D. Hinduja National Hospital & Medical Research Center, Veer Savarkar Marg, Mahim, Mumbai - 400 016, India. vrajesh@vsnl.com
Vrajesh
V
Udani
Manisha
M
Bavdekar
Samir
S
Karia
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004827:Epilepsy / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D019462:Syncope, Vasovagal / Q000175:diagnosis*; D018667:Tilt-Table Test