Iridoid glucosides of Paederota lutea and the relationships between Paederota and Veronica.
In a chemical investigation of the water soluble compounds in Paederota lutea eight known iridoids were isolated together with a new one with a 8,9-double bond, namely paederotoside (10-O-benzoyl-6'-O-alpha-arabino(1-->6)-beta-glucopyranosyl arborescosidic acid) and the 6-hydroxy-flavone glucoside 4'-O-methylscutellarein 7-O-beta-glucopyranoside. The known iridoid glucosides were 8-epiloganic acid, gardoside, aucubin, catalpol and the 6-O-esters of catalpol: veronicoside, catalposide, amphicoside and verproside. The compounds isolated show that Paederota has a glycoside content almost identical to that of a general Veronica species, and this is in good agreement with the results from recent investigations of the phylogeny of Veronica and its closest relatives, where Paederota is placed as a sister-group next to Veronica. In an analysis of the iridoid glucosides from some of these relatives, it is shown that Veronica, Paederota, Picrorhiza and Veronicastrum are all characterized by containing 6-O-esters of catalpol. Some less closely related taxa namely: Lagotis, Wulfenia, Plantago, Aragoa and Globularia instead contain 10-O-esters of catalpol or aucubin.
Institut für Botanik der Universität Wien, Rennweg 14, A-1030 Wien, Austria.
Dirk C
DC
Albach
Charlotte Held
CH
Gotfredsen
Søren Rosendal
SR
Jensen
D039823:Iridoids / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010802:Phylogeny; D010943:Plantago / Q000737:chemistry* / Q000145:classification / Q000235:genetics; D013045:Species Specificity; D032264:Veronica / Q000737:chemistry* / Q000235:genetics
D039823:Iridoids