Lack of evidence that DNA in antibiotic preparations is a source of antibiotic resistance genes in bacteria from animal or human sources.
Although DNA encoding antibiotic resistance has been discovered in antibiotic preparations, its significance for the development of antibiotic resistance in bacteria is unknown. No phylogenetic evidence was obtained for recent horizontal transfer of antibiotic resistance genes from antibiotic-producing organisms to bacteria from human or animal sources.
Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
Susanna K P
SK
Lau
Patrick C Y
PC
Woo
Amanda P C
AP
To
Alexson T K
AT
Lau
Kwok-yung
KY
Yuen
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000096:biosynthesis; D004269:DNA, Bacterial / Q000032:analysis*; D004268:DNA-Binding Proteins / Q000235:genetics; D004340:Drug Contamination; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D022761:Gene Transfer, Horizontal; D005798:Genes, Bacterial; D006801:Humans; D010802:Phylogeny; D013753:Tetracycline Resistance; D014157:Transcription Factors / Q000235:genetics
D000596:Amino Acids; D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D004268:DNA-Binding Proteins; C086680:ETV5 protein, human; D014157:Transcription Factors