A complete and durable clinical response to high-dose dexamethasone in a patient with scleromyxedema.
We report a case of a patient with scleromyxedema limited to the skin with an associated IgG lambda monoclonal protein treated successfully with high-dose dexamethasone. We encourage the continued investigation of this complex relationship between the clinical presentation of scleromyxedema and its frequently associated paraproteinemia.
Horn
Keren B
KB
Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Horn
Meyer A
MA
Swan
James
J
Singhal
Seema
S
Guitart
Joan
J
D001706:Biopsy; D003907:Dexamethasone / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D008875:Middle Aged; D045743:Scleroderma, Diffuse / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D012867:Skin / Q000473:pathology
D003907:Dexamethasone