Mucositis and airway obstruction in a pediatric patient.
Pediatric patients undergoing induction regimens of chemotherapy may require intubation and mechanical ventilation either for respiratory failure or airway compromise as a complication of their therapy. We describe a case of difficult airway management resulting from pseudomembrane formation in a 16-yr-old girl. The patient was undergoing induction chemotherapy for stage IV rhabdomyosarcoma and developed severe mucositis that led to progressive airway obstruction.
Chaimberg
Kathleen H
KH
Department of Anesthesiology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire.
Cravero
Joseph P
JP
D000293:Adolescent; D000402:Airway Obstruction / Q000209:etiology* / Q000473:pathology; D000903:Antibiotics, Antineoplastic; D018906:Antineoplastic Agents, Alkylating; D000972:Antineoplastic Agents, Phytogenic; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects; D003520:Cyclophosphamide; D003609:Dactinomycin; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal; D009092:Mucous Membrane / Q000473:pathology*; D012208:Rhabdomyosarcoma / Q000150:complications / Q000188:drug therapy; D014750:Vincristine
D000903:Antibiotics, Antineoplastic; D018906:Antineoplastic Agents, Alkylating; D000972:Antineoplastic Agents, Phytogenic; D003609:Dactinomycin; D014750:Vincristine; D003520:Cyclophosphamide