Single-step recovery of ephedrine hydrochloride from raw materials using expanded bed adsorption.
Expanded bed adsorption, using a cation resin 001 x 7 Styrene-DVB, was used to recover and purify ephedrine hydrochloride from a powdered herb. The axial liquid-phase dispersion coefficient was about 10(-5) m(2) s(-1) and the recovery yield and purification reached 86% and 22, respectively. Compared with using conventional extraction with dimethylbenzene, this method is safer and also more efficient.
Chen
Wei-Dong
WD
State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100080, P.O. Box 353, P.R. China. wdchen@home.ipe.ac.cn
Wang
Yan-Dong
YD
Zha
Li-Hang
LH
Ma
Guang-Hui
GH
Su
Zhi-Guo
ZG
D002411:Cation Exchange Resins; D005591:Chemical Fractionation / Q000379:methods; D002845:Chromatography / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification*; D029789:Ephedra / Q000378:metabolism*; D004809:Ephedrine / Q000302:isolation & purification*; D014462:Ultrafiltration / Q000379:methods*
D002411:Cation Exchange Resins; D004365:Drugs, Chinese Herbal; D004809:Ephedrine