Remarkable increase in central Japan in 2001-2002 of Neisseria gonorrhoeae isolates with decreased susceptibility to penicillin, tetracycline, oral cephalosporins, and fluoroquinolones.
Four hundred sixty-two clinical isolates of Neisseria gonorrhoeae recovered from 1999 through 2002 in central Japan were examined for MICs of antimicrobial agents. The majority was sensitive to ceftriaxone and spectinomycin, but a remarkable increase in isolates with decreased susceptibility to penicillin, tetracycline, oral cephalosporins, and fluoroquinolones was observed from 2001 through 2002.
Department of Urology, Gifu University School of Medicine, Gifu City, Gifu, Japan.
Masayasu
M
Ito
Mitsuru
M
Yasuda
Shigeaki
S
Yokoi
Shin-ichi
S
Ito
Yoshito
Y
Takahashi
Satoshi
S
Ishihara
Shin-ichi
S
Maeda
Takashi
T
Deguchi
D018550:Cephalosporin Resistance; D024881:Drug Resistance, Bacterial; D024841:Fluoroquinolones / Q000494:pharmacology; D006069:Gonorrhea / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects*; D010403:Penicillin Resistance; D013753:Tetracycline Resistance
D024841:Fluoroquinolones