Solid-state NMR spectroscopic studies of an integral membrane protein inserted into aligned phospholipid bilayer nanotube arrays.
This communication demonstrates for the first time that solid-state NMR spectroscopic studies can be used to investigate aligned phospholipid bilayer nanotube arrays. Also, an integral membrane peptide can be successfully incorporated into the oriented phospholipid bilayer nanotube arrays and studied with 2H solid-state NMR spectroscopy.
Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio 45056, USA. lorigan@muohio.edu
Gary A
GA
Lorigan
Paresh C
PC
Dave
Elvis K
EK
Tiburu
Krishnan
K
Damodaran
Shadi
S
Abu-Baker
Ethan S
ES
Karp
William J
WJ
Gibbons
Robert E
RE
Minto
D000537:Aluminum Oxide / Q000737:chemistry; D000595:Amino Acid Sequence; D004134:Dimyristoylphosphatidylcholine / Q000737:chemistry; D044943:Fatty Acid Desaturases / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry*; D008565:Membrane Proteins / Q000737:chemistry*; D008969:Molecular Sequence Data; D043942:Nanotubes / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods; D010742:Phospholipid Ethers / Q000737:chemistry; D010743:Phospholipids / Q000737:chemistry*; D017434:Protein Structure, Tertiary
C052298:1,2-dihexadecyl-sn-glycero-3-phosphocholine; D008051:Lipid Bilayers; D008565:Membrane Proteins; D010742:Phospholipid Ethers; D010743:Phospholipids; D044943:Fatty Acid Desaturases; C111962:acetylenase; D000537:Aluminum Oxide; D004134:Dimyristoylphosphatidylcholine