[Surveillance of infections in chronic hemodialysis patients].
OBJECTIVE
To confirm rates of infections from a previous survey in chronic hemodialysis patients; to get information about incidents and manipulations of vascular access-site, number and reasons of hospitalisation; to asses a relationship between the frequency of vascular access-site infections (VASI) and quality of care during the procedures of vascular access-site use.


METHODS
Prospective, multicenter survey performed from February 2000 to January 2001, including all patients underwent chronic hemodialysis in 5 participating centers. Standardized definitions used and different clinical and biological risk factors recorded.


RESULTS
429 patients for a total of 4273 dialysis months (DM) were enrolled. 245 infections in 164 infected patients were reported. The overall rate was 5.73 infections per 100 DM (18 VASI, 25 bacteraemia, 84 respiratory, 29 urinary tract, 1 endocarditis and 88 other infections). 50% of infections were microbiologically documented. 19 of 21 antibiotics resistant microorganisms were meticillin resistant Staphylococcus aureus. Compared to the incidence rate of fistula (0.05 per 1000 days of follow-up) or prosthesis related VASI (0.11), the incidence rate of catheter related VASI (0.65) was significantly higher. Poor hygiene and duration of catheter use were the significant risk factors for VASI showed by logistic analysis regression. VASI and bacteraemia occurred more frequently after incident or manipulation of the vascular access-site. The decrease of VASI between the 2 periods of survey was significantly higher in centers having reduced the catheter use and implemented written protocols.


CONCLUSIONS
This second period of surveillance has confirmed the frequency of infections rate in chronic hemodialysis patients and particularly bacteraemia and VASI. This study has allowed to establish risk factors for infections and showed that VASI in hemodialysis are related to factors in part preventable.
EIDLIN Drôme-Ardèche, Centre hospitalier, Valence. jhajjar@ch-valence.fr
J
J
Hajjar
R
R
Girard
J M
JM
Marc
L
L
Ducruet
M
M
Béruard
B
B
Fadel
M
M
Forêt
D
D
Lerda
C
C
Roche
M
M
Vallet
L
L
Ayzac
J
J
Fabry
D000368:Aged; D003928:Diabetic Nephropathies; D005260:Female; D005602:France; D006801:Humans; D015994:Incidence; D007239:Infections / Q000145:classification / Q000453:epidemiology*; D008297:Male; D006435:Renal Dialysis / Q000009:adverse effects*; D012307:Risk Factors; D013997:Time Factors