1,3-Propanediol production by Klebsiella pneumoniae under different aeration strategies.
1,3-Propanediol production by Klebsiella pneumoniae was studied in batch cultures under N2 flow and four airflow systems. Different byproducts were formed under different aeration conditions. An anaerobic/aerobic combined fed-batch culture was developed giving 70 g 1,3-propanediol l(-1) and 16 g 2,3-butanediol l(-1) with total diol yield of 0.6 mol(-1) glycerol.
Department of Chemical Engineering, Tsinghua University, Beijing 100084, PR China.
Ke-Ke
KK
Cheng
De-Hua
DH
Liu
Yan
Y
Sun
Wei-Bin
WB
Liu
D000332:Aerobiosis / Q000502:physiology; D019149:Bioreactors / Q000382:microbiology*; D018929:Cell Culture Techniques / Q000379:methods*; D049109:Cell Proliferation; D007711:Klebsiella pneumoniae / Q000254:growth & development* / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism*; D011409:Propylene Glycols / Q000378:metabolism*
D011409:Propylene Glycols; C041787:1,3-propanediol; D010100:Oxygen