Analysis of p51, groESL, and the major antigen P51 in various species of Neorickettsia, an obligatory intracellular bacterium that infects trematodes and mammals.
The p51 gene that encodes the major antigenic 51-kDa protein in Neorickettsia risticii was identified in strains of Neorickettsia sennetsu and the Stellantchasmus falcatus agent but not in Neorickettsia helminthoeca, suggesting that p51-based diagnosis would be useful to distinguish among them. groESL sequencing results delineated the phylogenic relationships among Neorickettsia spp.
Rikihisa
Yasuko
Y
Department of Veterinary Biosciences, The Ohio State University, 1925 Coffey Rd., Columbus, OH 43210, USA. rikihisa.1@osu.edu
Zhang
Chunbin
C
Kanter
Manuel
M
Cheng
Zhihui
Z
Ohashi
Norio
N
Fukuda
Takeo
T
D000711:Anaplasmataceae Infections / Q000175:diagnosis / Q000662:veterinary; D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis*; D001426:Bacterial Proteins / Q000032:analysis*; D018833:Chaperonins / Q000032:analysis*; D004268:DNA-Binding Proteins / Q000032:analysis*; D016147:Genes, Tumor Suppressor; D006801:Humans; D008322:Mammals / Q000382:microbiology*; D041102:Neorickettsia / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D010750:Phosphoproteins; D010802:Phylogeny; D015183:Restriction Mapping; D015534:Trans-Activators; D014157:Transcription Factors; D014200:Trematoda / Q000382:microbiology*; D025521:Tumor Suppressor Proteins
D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; C097970:GroESL protein, Bacteria; D010750:Phosphoproteins; C115051:TP63 protein, human; D015534:Trans-Activators; D014157:Transcription Factors; D025521:Tumor Suppressor Proteins; D018833:Chaperonins