Impact of spinal anaesthesia and obesity on maternal respiratory function during elective Caesarean section.
Spinal anaesthesia for Caesarean section has gained widespread acceptance. We assessed the impact of spinal anaesthesia and body mass index (BMI) on spirometric performance. In this prospective study, we consecutively assessed 71 consenting parturients receiving spinal anaesthesia with hyperbaric bupivacaine and fentanyl for elective Caesarean section. We performed spirometry during the antepartum visit (baseline), immediately after spinal anaesthesia, 10-20 min, 1 h, 2 h after the operation, and after mobilisation (3 h). Baseline values were within normal ranges. There was a significant decrease in all spirometric parameters after effective spinal anaesthesia that persisted throughout the study period. The decrease in respiratory function was significantly greater in obese (BMI > 30 kg x m(-2)) than in normal-weight parturients (BMI < 25 kg x m(-2)), e.g. median (IQR) vital capacity directly after spinal anaesthesia; -24 (-16 to -31)% vs. -11 (-6 to -16)%, p < 0.001 and recovery was significantly slower. We conclude that both spinal anaesthesia and obesity significantly impair respiratory function in parturients.
Department of Anaesthesia, University of Basel/Kantonsspital, CH 4031 Basel, Switzerland. bvonungern@uhbs.ch
B S
BS
von Ungern-Sternberg
A
A
Regli
E
E
Bucher
A
A
Reber
M C
MC
Schneider
D000328:Adult; D000701:Analgesics, Opioid; D000773:Anesthesia, Obstetrical; D000775:Anesthesia, Spinal; D015992:Body Mass Index; D002585:Cesarean Section; D005260:Female; D006801:Humans; D008691:Methadone; D009765:Obesity / Q000503:physiopathology*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D011446:Prospective Studies; D012119:Respiration; D012129:Respiratory Function Tests / Q000379:methods; D013147:Spirometry
D000701:Analgesics, Opioid; D008691:Methadone