[MALT gastric lymphomas].
BACKGROUND
The stomach is the most common site involved in primary gastrointestinal lymphoma. Gastric lymphoma originates from the mucosa-associated lymphoïd tissue so called MALT. It comprises a group of distinctive clinicopathological entities which are important to consider for clinical management.


BACKGROUND
In recent years, new diagnostic tools and new treatment strategies have improved the overall prognosis. One of the most exciting recent discoveries is the hypothesis that an infection by a bacterium, Helicobacter pylori has a decisive role in gastric lymphoma.


CONCLUSIONS
Recent advances, essentially due to molecular biology and cytogenetic studies may emerge with the understanding of pathogenesis and new prognostic factors of these different types of gastric lymphomas. It is the aim of our oncoming studies together with the evaluation of the new therapeutic options such as radiotherapy and monoclonal antibodies in prospective studies.
Ruskoné-Fourmestraux
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Service de gastroentérologie, Hôtel-Dieu AP-HP, 1, place du parvis-Notre-Dame, 75004 Paris, France. agnes.fourmestraux@htd.ap-hop-paris.fr
D003937:Diagnosis, Differential; D016481:Helicobacter Infections / Q000150:complications*; D016480:Helicobacter pylori / Q000472:pathogenicity; D006801:Humans; D015994:Incidence; D018442:Lymphoma, B-Cell, Marginal Zone / Q000382:microbiology* / Q000503:physiopathology* / Q000628:therapy; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000382:microbiology* / Q000503:physiopathology* / Q000628:therapy