[Skin-like structure generated from implantation of hair follicle bulb cells into collagen/chitosan porous scaffolds in vitro].
To observe the skin regeneration after hair follicle bulb cells were implanted into collagen/chitosan porous scaffolds in vitro.



The cultured dorsal hair follicle bulb cells of 4d-old C57BL/6J mice were implanted into collagen/chitosan porous scaffolds in vitro. The skin regeneration was observed.



The skin-like structure was formed on the collagen/chitosan porous scaffolds where were cultured the hair follicle bulb cells before 4th passages.



The skin-like structure is generated in vitro when early passages of cultured hair bulb cells are implanted into collagen/chitosan porous scaffolds.
Wu
Xian-jie
XJ
Department of Dermatology, the Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China.
Lu
Zhong-fa
ZF
Zheng
Min
M
Chao
Yue-lan
YL
Cai
Sui-qing
SQ
Zhou
Jian-guang
JG
Ma
Lie
L
Gao
Chang-you
CY
D000818:Animals; D002686:Chitin / Q000031:analogs & derivatives*; D048271:Chitosan; D003094:Collagen; D018859:Hair Follicle / Q000166:cytology*; D051379:Mice; D008810:Mice, Inbred C57BL; D012038:Regeneration; D012867:Skin / Q000166:cytology*; D023822:Tissue Engineering
D002686:Chitin; D003094:Collagen; D048271:Chitosan