Combined atrial septostomy and oral sildenafil for severe right ventricular failure due to primary pulmonary hypertension.
Management of primary pulmonary hypertension is usually difficult because the disease is uncommon and the aetiology of the disease is not well understood. The disease is potentially lethal because it can lead to failure of the right ventricle, low cardiac output, and ensuing multiple organ failure. We report the successful treatment of a case of low-output syndrome due to primary pulmonary hypertension using combined drug therapy and atrial septostomy. Latest developments in the treatment of this disease are also discussed.
Chau
E M C
EM
Department of Cardiology, Grantham Hospital, 125 Wong Chuk Hang Road, Hong Kong. echau@hkucc.hku.hk
Fan
K Y Y
KY
Chow
W H
WH
D000328:Adult; D002303:Cardiac Output, Low / Q000209:etiology* / Q000628:therapy; D005260:Female; D006325:Heart Atria / Q000601:surgery; D006346:Heart Septum / Q000601:surgery*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology* / Q000628:therapy; D010879:Piperazines / Q000627:therapeutic use*; D011687:Purines; D000068677:Sildenafil Citrate; D013450:Sulfones; D014665:Vasodilator Agents / Q000627:therapeutic use*; D018497:Ventricular Dysfunction, Right / Q000150:complications* / Q000628:therapy
D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate