Reduced high-frequency QRS components in patients with ischemic heart disease compared to normal subjects.
Analysis of high-frequency QRS components (HF-QRS) might provide an additional method when diagnosing various heart diseases, for example ischemic heart disease (IHD). This study compares HF-QRS in normal subjects to those in patients with IHD, and also analyzes HF-QRS considering gender and age. A total of 63 normal subjects and 64 patients with IHD were included. Signal-averaged electrocardiograms (ECGs) from the 12 standard leads were analyzed in the frequency interval of 150-250 Hz. The results showed that the summed 12 lead HF-QRS in patients with IHD were significantly lower than in normal subjects (mean summed HF-QRS was 33.5 microV in the IHD group, 43.7 microV in normal individuals, P <.0005). HF-QRS were not statistically associated with gender or age (P =.820 and P =.573, respectively). However, the inter-individual variation of HF-QRS was large in both groups which probably limits the clinical usefulness of the method.
Trägårdh
Elin
E
Department of Clinical Physiology, Lund University, Lund, Sweden. elin.tragardh.202@student.lu.se
Pahlm
Olle
O
Wagner
Galen S
GS
Pettersson
Jonas
J
D016022:Case-Control Studies; D004562:Electrocardiography / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000175:diagnosis* / Q000503:physiopathology; D012815:Signal Processing, Computer-Assisted