A case of primary cardiac lymphoma located in the pericardial effusion.
Primary cardiac lymphoma is a rare disorder with a poor prognosis. We present here a case of 77-year-old woman who was diagnosed as having cardiac lymphoma antemortem according to a cytologic examination of the pericardial effusion. Determination of the levels of serum-soluble interleukin-2 receptor and serum deoxythymidine kinase was useful for the diagnosis. Echocardiography, computed tomography, magnetic resonance imaging, and gallium scan revealed neither lymphadenopathy nor tumor in the heart, so she was diagnosed as having malignant lymphoma that probably originated from the pericardium. Systemic chemotherapy with CHOP (cyclophosphamide, farmorubicin, oncovin, and prednisolone) resulted in a complete resolution of the pericardial effusion. She has been in remission 48 months after discontinuation of the chemotherapy.
First Department of Internal Medicine, Mie University School of Medicine, 2-174 Edobashi, Tsu, 514-8507, Mie, Japan, nakaku-t@clin.medic.mie-u.ac.jp
Tetsuya
T
Nakakuki
Hiroshi
H
Masuoka
Ken
K
Ishikura
Tetsuya
T
Seko
Sukenari
S
Koyabu
Takuya
T
Tamai
Masahiro
M
Sugawa
Masaaki
M
Ito
Takeshi
T
Nakano
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D006338:Heart Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis* / Q000188:drug therapy; D010490:Pericardial Effusion / Q000188:drug therapy / Q000473:pathology*; D011239:Prednisolone / Q000627:therapeutic use; D014750:Vincristine / Q000627:therapeutic use
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone