Intraoperative recombinant activated factor VII for emergent epidural hematoma evacuation.
We report a case of a chronically anticoagulated 59-yr-old woman who underwent an L4 to L5 epidural block to relieve her low back pain and subsequently developed a T7 to L5 epidural hematoma with cauda equina and conus compression. Fresh frozen plasma and vitamin K were given before surgery, whereas recombinant activated factor VII was administered during surgery to reverse the coagulopathy and to enable the emergent laminectomy and hematoma evacuation. Recombinant activated factor VII administration proved to be a useful adjunct in the emergent surgical management of a thoracolumbar epidural hematoma.
Szabo
Tamas
T
Department of Anesthesiology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA. tamas.szabo@excite.com
Ali
Syed
S
Camporesi
Enrico M
EM
D015360:Analgesia, Epidural / Q000009:adverse effects*; D000925:Anticoagulants / Q000009:adverse effects; D024143:Collagen Type VII / Q000627:therapeutic use*; D005260:Female; D006407:Hematoma, Epidural, Cranial / Q000188:drug therapy* / Q000209:etiology; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D007432:Intraoperative Period; D017116:Low Back Pain / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010949:Plasma; D011994:Recombinant Proteins / Q000627:therapeutic use; D014812:Vitamin K / Q000627:therapeutic use
D000925:Anticoagulants; D024143:Collagen Type VII; D006490:Hemostatics; D011994:Recombinant Proteins; D014812:Vitamin K