Chemical nature, ligand denticity and quantification of fungal siderophores.
Thirtyfive siderophore producing fungi were categorized for their hydroxamate, catecholate or carboxylate nature by chemical and bioassays. Out of 35 fungi, 30 were hydroxamates and 5 showed carboxylate nature. However, none of the fungi produced catecholate type of siderophores. Eighteen out of 29 fungi were trihydroxamate and the rest 11 fungi were dihydroxamates. Twenty-three fungi were hexadentate and 6 were tetradentate in nature. Quantification of siderophores using standard compounds deferrioxamine mesylate and rhizoferrin revealed that Phanerochaete chrysosporium produced maximum among the hydroxamate producing fungi and Mycotypha africana resulted maximum among the carboxylate producing fungi.
Department of Life Sciences, Bhavnagar University, Bhavnagar 364002, India.
Arefa
A
Baakza
B P
BP
Dave
H C
HC
Dube
D001681:Biological Assay; D002264:Carboxylic Acids / Q000737:chemistry*; D002712:Chlorides; D003676:Deferoxamine / Q000737:chemistry / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004837:Epinephrine / Q000031:analogs & derivatives* / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry / Q000378:metabolism; D005658:Fungi / Q000378:metabolism*; D006877:Hydroxamic Acids / Q000737:chemistry*; D007501:Iron / Q000378:metabolism; D008024:Ligands; D017262:Siderophores / Q000737:chemistry*; D013053:Spectrophotometry
D002264:Carboxylic Acids; D002712:Chlorides; D005290:Ferric Compounds; D006877:Hydroxamic Acids; D008024:Ligands; D017262:Siderophores; C087496:rhizoferrin; C037919:N,N-dimethylepinephrine; D007501:Iron; D003676:Deferoxamine; C024555:ferric chloride; D004837:Epinephrine