Eicosanoid production by parasites: from pathogenesis to immunomodulation?
In this review, Adam Belley and Kris Chadee discuss eicosanoid production by various parasites and propose roles they may play in pathogenesis and immunomodulation. The commonality between parasites is prostaglandin production and, therefore, special attention is given to the cyclooxygenase pathway, highlighting the enzymes and functions of prostaglandins.
Institute of Parasitology of McGill University, Macdonald Campus, 21111 Lakeshore Road, Ste-Anne de Bellevue, Quebec, Canada H9X 3V9.
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Belley
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Chadee