Emerging asymmetry and embryonic patterning in early mouse development.
Recent studies have revealed asymmetries in the mouse zygote and preimplantation embryo, well before the establishment of anterior-posterior polarity after implantation. Whether these asymmetries are causally related to embryonic patterning or are coincidental outcomes of the topology of normal development remains uncertain.
Rossant
Janet
J
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, 600 University Avenue, Ontario M5G 1X5, Canada. rossant@mshri.on.ca
Tam
Patrick P L
PP
D000818:Animals; D001755:Blastocyst / Q000502:physiology; D019521:Body Patterning; D002467:Cell Nucleus / Q000378:metabolism; D010064:Embryo Implantation; D005260:Female; D005775:Gastrula / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental; D051379:Mice; D008954:Models, Biological; D013997:Time Factors; D014599:Uterus / Q000502:physiology; D015053:Zygote / Q000502:physiology