A wide range of baroreflex stimulation does not alter forearm blood flow.
The contribution to the regulation of forearm blood flow (FBF) by different baroreceptor populations has previously only been studied over a limited range of stimuli. Therefore, FBF and R-R interval were recorded during neck suctions and neck pressures ranging from -60 to +40 mmHg. The change in R-R interval (DeltaR-R) during neck suction was significantly increased at each stage when compared to the control ( P<0.05). DeltaR-R did not show any significant change during any of the neck pressure stages ( P>0.05). Suction or pressure applied to the neck did not elicit any significant changes in FBF when compared to the control ( P>0.05). These data show that widening the range of applied stimuli to carotid sinus baroreceptors does not induce a change in FBF. However, the small transient changes reported previously cannot be discounted.
Physiology of Exercise, De Montfort University, Lansdowne Road, Bedford, UK. howden@niehs.nih.gov
Reuben
R
Howden
J Timothy
JT
Lightfoot
Michael J
MJ
Turner
Stephen J
SJ
Brown
Ian L
IL
Swaine
D000328:Adult; D017704:Baroreflex / Q000502:physiology*; D001783:Blood Flow Velocity / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D005260:Female; D005542:Forearm / Q000098:blood supply* / Q000294:innervation / Q000502:physiology*; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D009333:Neck / Q000502:physiology; D010812:Physical Stimulation / Q000379:methods*; D011311:Pressoreceptors / Q000502:physiology*; D011312:Pressure