The transglutaminase family: an overview: minireview article.
The knowledge that very different processes such as normal and neoplastic cell growth, reproduction and death are dependent on the presence of adequate levels of transglutaminases (TGase: EC 2.3.2.13) and that they are capable of affecting the differentiation and proliferative capability of several cell types, has prompted a multitude of researchers to study these fascinating molecules. In the following overview we intend to summarize the currently known information on the biological significance of these enzymes.
Beninati
S
S
Department of Biology, University of Rome Tor Vergata, Rome, Italy.
Piacentini
M
M
D000818:Animals; D001709:Biotechnology; D001777:Blood Coagulation / Q000502:physiology; D016923:Cell Death; D004194:Disease; D004817:Epidermis / Q000201:enzymology; D006801:Humans; D010944:Plants / Q000201:enzymology; D011503:Transglutaminases / Q000737:chemistry / Q000378:metabolism*
D011503:Transglutaminases