Biological screening of Nigella damascena for antimicrobial and molluscicidal activities.
The essential oil, various extracts at different polarity, fractions, and pure compounds obtained from Nigella damascena plants and seeds were screened for biological activity. Antimicrobial tests showed the essential oil to be active only against Gram positive bacteria; among the extracts, the BuOH was active against Pseudomonas aeruginosa and Staphylococcus aureus. Molluscicidal activity was absent.
Dipartimento di Biologia, Università degli Studi di Milano, Milano, Italy. gelsomina.fico@unimi.it
G
G
Fico
L
L
Panizzi
G
G
Flamini
A
A
Braca
I
I
Morelli
F
F
Tomè
P L
PL
Cioni
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D002176:Candida albicans / Q000187:drug effects; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006801:Humans; D008826:Microbial Sensitivity Tests; D008975:Molluscacides / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D031861:Nigella damascena; D008517:Phytotherapy; D010938:Plant Oils / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D012908:Snails / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D008975:Molluscacides; D010938:Plant Oils