[Clinical and pathological features of 273 cases of lacrimal epithelial tumors].
OBJECTIVE
A retrospective study of histopathological and clinical aspects of 261 cases of lacrimal tumors (273 paraffin specimens) from Ophthalmic Pathology Laboratory, Beijing Tongren Hospital (Dec. 1961 to Jun. 2002) was performed to investigate the pathological classification and clinical features of these tumors.


METHODS
Clinical features were analyzed from 261 patients of lacrimal tumors, including patient's history, age, gender, laterality, visual acuity, ultrasound B scan, X-ray, CT, MRI, pre- and post-operation condition, follow-up data and others. These data were compared with the pathological features.


RESULTS
Pleomorphic adenoma was the most common tumor in epithelial tumors of lacrimal gland, followed by adenoid cystic carcinoma, pleomorphic adenocarcinoma and adenocarcinoma. Recurrence was observed in 12 cases. The recurrence rate is 4.6%. Four cases was dead, the mortality was 1.5%.


CONCLUSIONS
Pleomorphic adenoma shows a low mortality and a relatively high recurrence rate. The main treatment for pleomorphic adenoma is surgical treatment. It is important to have a correct clinical diagnosis, to select the proper surgical method, drug treatment and postoperative management based on the pathological diagnosis, which can result in a decrease of recurrence rate.
Zhu
Jian-Bo
JB
Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Affiliated Capital University of Medical Science, Beijing 100730, China.
Li
Bin
B
Sun
Xian-Li
XL
Li
Liao-Qing
LQ
Shi
Ji-Tong
JT
An
Yu-Zhi
YZ
D000230:Adenocarcinoma / Q000473:pathology; D008949:Adenoma, Pleomorphic / Q000473:pathology; D000293:Adolescent; D000328:Adult; D000368:Aged; D003528:Carcinoma, Adenoid Cystic / Q000473:pathology; D002648:Child; D002681:China; D005134:Eye Neoplasms / Q000145:classification / Q000473:pathology*; D005260:Female; D006801:Humans; D007765:Lacrimal Apparatus / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies