Analysis of the optical quality of intraocular lenses.
OBJECTIVE
To evaluate the optical quality of different intraocular lenses (IOLs).


METHODS
An optical test bench and suitable software were used to assist in analysis of the optical Fourier transform (OFT) of a test image and to determine the quality of the lens in terms of spatial frequency response. The OFT was automatically converted, by means of an optical-electronic calibration procedure, into a modulation transfer function (MTF) for each lens. The passband value calculated by computer analysis of the MTF is an objective index of the lens quality. Three randomly acquired samples of 24 different models of foldable IOLs were compared. Statistical analysis was performed with two-way and one-way ANOVA for repeated measurements and with the Ryan-Einot-Gabriel-Welsch multiple F test.


RESULTS
The method was demonstrated to be precise and accurate. A large range of passband values was found. Statistically significant differences between the mean passband values for different lenses were found. The lowest passband value (125.60 line pairs [lp]/mm) was measured for the IOL (Lenstec LH3000; Lenstec, Inc., St. Petersburg, FL) and the highest (191.48 lp/mm) for the Acrysof SA30AL (Alcon, Fort Worth, TX).


CONCLUSIONS
Different IOLs can transmit different spectra of spatial frequencies. The best frequency response was provided by acrylic IOLs, particularly those with an asymmetrically biconvex profile. This could be due to a reduction of optical degradation provided by this type of profile. A lens with a higher frequency response should determine a better quality of vision once implanted and the frequency response should therefore be considered when choosing the intraocular lens model.
Tognetto
Daniele
D
Eye Clinic, University of Trieste, Italy. tognetto@univ.trieste.it
Sanguinetti
Giorgia
G
Sirotti
Paolo
P
Cecchini
Paolo
P
Marcucci
Luana
L
Ballone
Enzo
E
Ravalico
Giuseppe
G
D005583:Fourier Analysis; D006801:Humans; D007910:Lenses, Intraocular; D055095:Optics and Photonics; D011786:Quality Control