[Severe primary hyperparathyroidism and vitamin D deficiency].
Primary hyperparathyrodism is a common disease, often asymptomatic. A young post-partum woman was hospitalized for functional impotence of the upper right limb and poor health status. Laboratory tests revealed severe primary hyperparathyroidism (osteitis fibrosa cystica and nephrolithiasis) associated with vitamin D deficiency. Technetium 99m and thallium parathyroid scintigraphy showed increased uptake under the left thyroid lobe. After surgical resection of a parathyroid adenoma, serum calcium fell markedly and parathyroid levels declined but remained above normal. Calcium and 25(OH)-vitamin D supplementation led to normal calcium and vitamin D levels in three Months, with marked improvement in the bone lesions visualized on the six-Month x-rays. Based on this observation, we describe the many radiological aspects of bone involvement in long-standing hyperparathyroidism aggravated by vitamin D deficiency. Early diagnosis of hyperparathyroidism is crucial.
Service de médecin interne, hôpital militaire Moulay Ismaïl, Meknès. hassikouhasna@hotmail.com
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Safi
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Hassikou
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Messary
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Boumdin
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Hadri
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Zouhair
D000236:Adenoma / Q000000981:diagnostic imaging / Q000601:surgery; D000328:Adult; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002118:Calcium / Q000008:administration & dosage; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D010002:Osteitis Fibrosa Cystica / Q000000981:diagnostic imaging / Q000209:etiology; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery; D011859:Radiography; D011877:Radionuclide Imaging; D014807:Vitamin D / Q000008:administration & dosage / Q000031:analogs & derivatives*; D014808:Vitamin D Deficiency / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
D014807:Vitamin D; C104450:25-hydroxyvitamin D; D002118:Calcium