(-)-Amarbellisine, a lycorine-type alkaloid from Amaryllis belladonna L. growing in Egypt.
A new lycorine-type alkaloid, named (-)-amarbellisine, was isolated from the bulbs of Egyptian Amaryllis belladonna L. together with the well known alkaloids (-)-lycorine, (-)-pancracine, (+)-vittatine, (+)-11-hydroxyvittatine, and (+)-hippeastrine. The new alkaloid, containing the pyrrolo[de]phenanthridine ring system, was essentially characterised by spectroscopic and optical methods, and proved to be the 2-methoxy-3a,4,5,7,11b,11c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridinol. By using HPTLC technique we also carried out a comparative study of the relative and total alkaloidal content at two different stages of plant growth. Finally, the antimicrobial activity of the isolated alkaloids was assayed.
Dipartimento di Scienze del Suolo della Pianta e dell'Ambiente, Università di Napoli Federico II, Via Università 100, I-80055 Portici, Italy. evidente@unina.it
Antonio
A
Evidente
Anna
A
Andolfi
Amina H
AH
Abou-Donia
Soad M
SM
Touema
Hala M
HM
Hammoda
Eman
E
Shawky
Andrea
A
Motta
D047151:Amaryllidaceae Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004534:Egypt; D019668:Liliaceae / Q000737:chemistry* / Q000254:growth & development; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
D047151:Amaryllidaceae Alkaloids