Use of rapid and conventional testing technologies for human immunodeficiency virus type 1 serologic screening in a rural Kenyan reference laboratory.
We report a prospective comparison of human immunodeficiency virus type 1 testing by enzyme immunoassay and Western blot with four rapid tests of 486 subjects performed in rural Kenya. Rapid test sensitivity was 100%. Specificity ranged from 99.1 to 100%. Combined use of two Food and Drug Administration-approved rapid tests yielded a single false-positive result.
U.S. Army Medical Research Unit--Kenya.
Ginamarie
G
Foglia
G Donald
GD
Royster
K Monique
KM
Wasunna
Rukia
R
Kibaya
Jennifer A
JA
Malia
Eva K
EK
Calero
Warren
W
Sateren
Philip O
PO
Renzullo
Merlin L
ML
Robb
Deborah L
DL
Birx
Nelson L
NL
Michael
D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis* / Q000453:epidemiology; D015153:Blotting, Western / Q000379:methods; D015658:HIV Infections / Q000175:diagnosis* / Q000453:epidemiology; D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods; D007630:Kenya / Q000453:epidemiology; D008403:Mass Screening / Q000379:methods; D011237:Predictive Value of Tests; D015995:Prevalence; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity