[International estimation of molecular target drug].
Development of tumor molecular biology makes a lot of molecular target drugs. Now molecular target drugs get constant estimation, and development competition is globally hot. Even if they have promising data in preclinical studies, it is very difficult to prove survival benefits in phase III studies. We have to understand a characteristic of molecular target drug based on Translational Research. Translational Research is an extremely important breakthrough to molecular target drug development/clinical application.
Department of Internal Medicine, National Cancer Center.
Yasuhito
Y
Fujisaka
Nagahiro
N
Saijo
D000970:Antineoplastic Agents / Q000008:administration & dosage; D017326:Clinical Trials, Phase III as Topic; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D015398:Signal Transduction / Q000187:drug effects
D000970:Antineoplastic Agents