Scrotal calcinosis: is the cause still unknown?
Scrotal calcinosis is a rare benign entity of calcified nodules within the scrotal skin. We describe a healthy 25-year-old man with multiple asymptomatic calcified nodules restricted to the scrotum. Histologic studies of multiple nodules showed calcium deposition, and basophilic material with sparse inflammation surrounded by a fibrous capsule. Because the intensive evaluation of our patient failed to reveal a cause, an analysis of all 123 cases found in the literature was conducted. Several plausible origins for scrotal calcinosis are disclosed; however, pathogenesis of this condition remains equivocal and controversial. The most common treatment option is excision of the affected nodules. Our report underscores the need for further investigation of this florid and bizarre disorder.
Department of Dermatology, Mount Sinai Medical Center, New York, New York 10029, USA.
Rao N
RN
Saladi
Andrea N
AN
Persaud
Robert G
RG
Phelps
Steven R
SR
Cohen
D000328:Adult; D002114:Calcinosis / Q000175:diagnosis* / Q000473:pathology; D005832:Genital Diseases, Male / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D012611:Scrotum