Five new Ocotillone-type saponins from Gynostemma pentaphyllum.
Five new ocotillone-type saponins, gynosides A-E (1-5), along with 10 known dammarane-type saponins, were isolated from the aerial parts of Gynostemma pentaphyllum. The structures of these new compounds were determined by NMR analysis and acid hydrolysis. The structure and stereochemistry of gynoside A (1) were confirmed by X-ray crystallography.
Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, People's Republic of China.
Xin
X
Liu
Wencai
W
Ye
Ziyao
Z
Mo
Biao
B
Yu
Shouxun
S
Zhao
Houming
H
Wu
Chuntao
C
Che
Renwang
R
Jiang
Thomas C W
TC
Mak
W L Wendy
WL
Hsiao
D018360:Crystallography, X-Ray; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification*; D029774:Gynostemma / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification*
D004365:Drugs, Chinese Herbal; D012503:Saponins; C488654:gynoside A