Cycles within cycles: the interplay between differentiation and cell division in Trypanosoma brucei.
The life cycle o f the African trypanosome is divided between the mammal and the tsetse. Those life cycle stages which traverse between these two hosts appear to be pre-adopted for survival in their new habitat They are also non-dividing. Here, Keith Matthews and Keith Gull discuss how and why trypanosomes might enmesh the control o f their cell cycle with their regulation o f the transition between different life cycle forms.
School of Biological Sciences, Division of Biochemistry, University of Manchester, Stopford Building Oxford Road, Manchester, UK M13 9PT.
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