Residues of dioxins and PCBs in fat of growing pigs and broilers fed contaminated feed.
To investigate the kinetics of PCBs and dioxins, 3 week old broilers and 3 month old pigs were fed with a 10-fold diluted feed from the Belgium crisis for one week, followed by a period on clean feed. In the case of broilers this resulted in levels for dioxins, non-ortho and mono-ortho PCBs in fat of 102, 84 and 216 ng TEQ/kg, summarized to 402 ng TEQ/kg. Total levels decreased to 217 and 109 ng TEQ/kg after 1 and 3 weeks on clean feed. Indicator PCB levels decreased from an initial 6.2 mg/kg fat to respectively 3.2 and 1.5 mg/kg. The ratio of indicator PCBs to dioxins TEQs was stable over this period. Levels in back fat of pigs at the end of the exposure period were 26, 15, 82 and 123 ng TEQ/kg for respectively dioxins, non-ortho PCBs, mono-ortho PCBs and the sum. Total TEQ levels decreased to respectively 95, 70, 40, 22 and 12 ng TEQ/kg after 1, 2, 4, 8 or 12 weeks on clean feed. After 12 weeks dioxin levels were around 1 ng TEQ/kg. Indicator PCB levels decreased from 3.48 mg/kg to 2.65, 2.01, 1.25, 0.76 and 0.45 mg/kg fat, again after 1, 2, 4, 8 or 12 weeks on clean feed. Levels of dioxins decreased more rapidly than those of indicator PCBs, also reflected by the ratio of indicator PCBs to dioxins, being 133,000 at the end of the exposure period and 357,000 after week 12. It is concluded that the use of indicator PCBs for dioxins, in the case of a combined exposure, is a safe alternative for screening and in the case of pigs results in an overestimation rather than underestimation of the dioxin levels.
RIKILT Institute of Food Safety, Bornsesteeg 45, 6708PD Wageningen, The Netherlands. ron.hoogenboom@wur.nl
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D000273:Adipose Tissue / Q000378:metabolism*; D000821:Animal Feed / Q000032:analysis; D000818:Animals; D002645:Chickens / Q000378:metabolism*; D002850:Chromatography, Gel; D004147:Dioxins / Q000493:pharmacokinetics*; D008401:Gas Chromatography-Mass Spectrometry; D011078:Polychlorinated Biphenyls / Q000493:pharmacokinetics*; D034421:Sus scrofa / Q000378:metabolism*
D004147:Dioxins; D011078:Polychlorinated Biphenyls