Palladium-catalyzed allylalkynylation of benzynes: a highly efficient route to substituted 1-allyl-2-alkynylbenzenes.
Benzynes, generated in situ from 2-(trimethylsilyl)aryl triflates and cesium fluoride, undergo allylalkynylation with allylic chlorides and alkynylstannanes in the presence of palladium catalyst to give 1-allyl-2-alkynylbenzenes in good to excellent yields. [reaction: see text]
Department of Chemistry, Tsing Hua University, Hsinchu, Taiwan 300, Republic of China.
Masilamani
M
Jeganmohan
Chien-Hong
CH
Cheng