[Gastrin-secreting neuroendocrine carcinoma: two cases identified and treated surgically with a radio-guided technique].
The authors present two cases of gastrin-producing carcinoma demonstrated by scintigraphy with In-111 pentetreotide. The possible malignant evolution of such tumours and the good results that can be achieved with surgical therapy suggest the usefulness of a radio-guided intraoperative strategy to locate the lesions and minimise invasive procedures. This approach enabled us to detect a lymph-node metastasis concealed in the adipose tissue in the first case and to exclude any other gastrin-producing tumour localisations in the second. We recommend that the radio-guided strategy should be included among the guidelines for the treatment of gastrinomas and believe that the procedure can also be used in other functioning endocrine tumours.
U.O. di Chirurgia Generale, Presidio Ospedaliero di Vigevano, Azienda Ospedaliera della Provincia di Pavia.
Umberto
U
Pandolfi
David
D
Cossard
Arcangelo
A
Pesenti Campagnoni
Ferruccio
F
Biandrate
Marco
M
Piccolini
Luigi
L
Francia
Francesca
F
Zadra
Giovanni
G
Ambrosino
Cesare
C
Rosa
Antonio
A
Battaglia
Mauro
M
Carena
D000368:Aged; D004379:Duodenal Neoplasms / Q000473:pathology / Q000601:surgery*; D015408:Gastrinoma / Q000556:secondary / Q000601:surgery*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D018358:Neuroendocrine Tumors / Q000473:pathology / Q000601:surgery*; D010190:Pancreatic Neoplasms / Q000473:pathology / Q000601:surgery*; D016634:Radiosurgery; D016896:Treatment Outcome