[Pulmonary plasmacytoma: about two new cases and review of the literature].
BACKGROUND
Extramedullary plasmacytoma is an uncommon plasma cell malignancy mainly located to the upper aerodigestive tract. Primary pulmonary plasmacytoma is extremely rare.


METHODS
We report two new cases of primary pulmonary plasmacytoma and then proceed to a review of the literature concerning 35 similar cases previously described.


CONCLUSIONS
Complete or partial responses were obtained in 24 cases (65%). Five patients (14%) have developed multiple myeloma within 3 years following plasmacytoma diagnostic. In spite of sustained responses with radiotherapy or chemotherapy, surgical resection while feasible remains the first therapeutic option.
Service de médecine interne et maladies tropicales, groupe hospitalier Saint-André, 1, rue Jean-Burguet, 33075 Bordeaux, France. gabriel.etienne@chu-bordeaux.fr
G
G
Etienne
M
M
Grenouillet
C
C
Ghiringhelli
R
R
Vatan
E
E
Lazaro
P
P
Germain
P
P
Mercié
M
M
Longy-Boursier
D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000628:therapy; D008297:Male; D010954:Plasmacytoma / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome