The role of lymphadenectomy in the surgical management of renal cell carcinoma.
After decades of evaluation, the role of lymphadenectomy in the management of renal cell carcinoma remains a controversy. Contemporary series suggest that the true incidence of isolated lymph node metastases in clinically localized disease is small, and the location of such metastases is unpredictable. While several institutional series have suggested a therapeutic benefit for extended lymphadenectomy, there remains a lack of randomized data to support its routine use. Despite this, there remains a role for lymphadenectomy in individuals with high risk of lymph node metastasis or known lymphadenopathy in whom few other options exist for aggressive, potentially curative therapy.
Phillips
Courtney K
CK
Department of Urology, New York University School of Medicine, New York, NY, USA.
Taneja
Samir S
SS
D002292:Carcinoma, Renal Cell / Q000473:pathology* / Q000601:surgery*; D002986:Clinical Trials as Topic; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery*; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis / Q000175:diagnosis / Q000503:physiopathology; D009367:Neoplasm Staging / Q000379:methods*