Development tracks for cancer prevention markers.
We provide a general framework for describing various roles for biomarkers in cancer prevention research (early detection, surrogate endpoint, and cohort identification for primary prevention) and the phases in their evaluation.
Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892-7354, USA. sb16i@nih.gov
Stuart G
SG
Baker
Barnett S
BS
Kramer
Philip C
PC
Prorok
D014408:Biomarkers, Tumor / Q000032:analysis*; D015331:Cohort Studies; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis* / Q000517:prevention & control*
D014408:Biomarkers, Tumor