Microarray analysis of Aeromonas hydrophila cytotoxic enterotoxin-treated murine primary macrophages.
We performed microarray analyses of murine peritoneal macrophages to examine cellular transcriptional responses to a cytotoxic enterotoxin of Aeromonas hydrophila. While 66% of altered genes were common to both primary macrophages and the murine macrophage cell line RAW 264.7, Act caused expression changes of 28 genes specifically in murine peritoneal macrophages.
Galindo
C L
CL
Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555-1070, USA.
Fadl
A A
AA
Sha
J
J
Chopra
A K
AK
D016980:Aeromonas hydrophila / Q000378:metabolism*; D000818:Animals; D001426:Bacterial Proteins / Q000494:pharmacology*; D002460:Cell Line; D002478:Cells, Cultured; D004768:Enterotoxins / Q000494:pharmacology*; D005786:Gene Expression Regulation; D017737:Macrophages, Peritoneal / Q000187:drug effects*; D051379:Mice; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D011506:Proteins / Q000235:genetics / Q000378:metabolism*
D001426:Bacterial Proteins; D004768:Enterotoxins; D011506:Proteins; C082174:cytolytic enterotoxin protein, Aeromonas