Self-assembly of small peptidomimetic cyclophanes.
The self-assembly of a series of small peptidomimetic cyclophanes in organic solvents was studied. X-ray diffraction, NMR spectroscopy, and molecular modelling were used to understand the structural features of these self-assembling compounds both at the molecular and supramolecular level. The factors that could influence the formation of gels rather than crystals were studied and a model for the arrangement of molecules in the gel was proposed. Furthermore, scanning electron microscopy revealed that in some cases these compounds undergo a transcription of chirality when going from organogelator to helicoidal gel fibres.
Departament de Química Inorgànica i Orgànica, Universitat Jaume I, 12071 Castelló, Spain.
Jorge
J
Becerril
M Isabel
MI
Burguete
Beatriu
B
Escuder
Francisco
F
Galindo
Raquel
R
Gavara
Juan F
JF
Miravet
Santiago V
SV
Luis
Gabriel
G
Peris
D002942:Circular Dichroism; D004988:Ethers, Cyclic / Q000138:chemical synthesis / Q000737:chemistry*; D005782:Gels / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D008958:Models, Molecular; D008968:Molecular Conformation; D018716:Molecular Mimicry; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*; D014961:X-Ray Diffraction
D004988:Ethers, Cyclic; D005782:Gels; D010455:Peptides