The development of the sturgeon heart.
This paper presents a sequential analysis of the development of the sturgeon (Acipenser naccarii) heart from the end of gastrulation to the early juvenile stages. At late neurulation, the heart appears as a straight, short tube located over the endoderm that forms the wall of the yolk sac, in front of the developing head. The heart axis is aligned with the axis of the developing head. Subsequently, the heart elongates and adopts a C-shape, and its axis becomes perpendicular to that of the head. Around the time of hatching, the heart loses the loop and appears as a mostly straight tube with the chambers arranged in a craniocaudal sequence: outflow tract, ventricle, atrium, and a small sinus venosus. During the first 4 days post-hatching (dph), the heart starts looping again, adopts a C-shape, and undergoes a counterclockwise movement that brings the atrium to the left of the outflow tract and the ventricle to a caudal position. Thus, a primary and a secondary cardiac loop occur in the sturgeon. Later, the atria come to occupy a middle position behind the outflow tract, and the sinus venosus shifts from a caudal to a dorsal position. A morphological arrangement similar to that found in adult sturgeons is attained in all specimens at days 7-9 dph. The external changes are accompanied by a series of internal modifications that include trabeculation (3-4 dph), development of endocardial cushions in the atrioventricular canal (4 dph) and in the conus arteriosus (3-4 dph), conus (22-24 dph) and atrioventricular (18-20 dph) valve formation, and development of the epicardium (4 dph) and the coronary vessels (10 dph). The main developmental features of the heart have been registered, and a basic body of information, which should be very useful in future developmental studies, has been established. Similarities and dissimilarities between the development of the sturgeon heart and that of other vertebrates are underscored.
Icardo
José M
JM
Department of Anatomy and Cell Biology, Faculty of Medicine, University of Cantabria, Polígono de Cazoña, s/n, 39011 Santander, Spain. icardojm@unican.es
Guerrero
Alejandro
A
Durán
Ana C
AC
Domezain
Alberto
A
Colvee
Elvira
E
Sans-Coma
Valentín
V
D000818:Animals; D005399:Fishes / Q000033:anatomy & histology / Q000196:embryology*; D006321:Heart / Q000033:anatomy & histology / Q000196:embryology*; D008855:Microscopy, Electron, Scanning; D009024:Morphogenesis; D009206:Myocardium / Q000648:ultrastructure; D038081:Organogenesis / Q000502:physiology*