Effects of three methods of restraint an in rhesus and african green monkeys intravenous glucose tolerance testing.
The intravenous administration of 0.75 gm glucose per kg and the measurement of serum glucose pretest and at 10, 20, 30, 60, 90 and 120 minutes constitute a satisfactory protocol for intravenous glucose tolerance testing of Rhesus (Macaca mulatto) and African Green (Cercopithecus aethiops) monkeys. No significant differences were noted between animals restrained with ketamine hydrochloride and those restrained with sodium pentobarbital, but the African Green males and females and the male Rhesus monkeys yielded significantly different results while being manually restrained.
The Departments of Laboratory Animal Medicine and Science and the Department of Pathology Litton Bionetics, Inc. 5516 Nicholson Lane Kensington, Maryland 20895.
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R
Fulmer
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Loeb
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DP
Martin
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Gard