Consequences of amblyopia on education, occupation, and long term vision loss.
OBJECTIVE
To describe the effect of amblyopia on education, occupation, and 5 year incident vision loss.


METHODS
3654 participants aged 49 years or older participated in the Blue Mountains Eye Study (BMES I, 1992-4) and 2335 (75.1% of survivors) were re-examined (BMES II, 1997-9). All participants underwent detailed eye examination. Amblyopia, defined as best corrected visual acuity of less than or equal to 6/9 and not attributable directly to any underlying structural abnormality of the eye or the visual pathway, was identified in 118 participants (3.2%) in BMES I, of whom 73 were re-examined in BMES II. Occupation and educational classifications used definitions of the Australian Bureau of Statistics.


RESULTS
The mean age of people with amblyopia seen at baseline was 67.0 years. Amblyopia did not affect lifetime occupational class (p = 0.5), but fewer people completed higher university degrees (p = 0.05). In people with amblyopia, there was an increased risk of 5 year incident visual impairment in the better seeing eye worse than 6/12, relative risk (RR) 2.7, 95% confidence interval (CI) 1.6 to 4.6. One of 11 (9.1%) people with amblyopia showed significant improvement in visual acuity in the poorer seeing eye after a two line (10 logMAR letter) vision loss in the better seeing eye.


CONCLUSIONS
This study further documents the longitudinal history of amblyopia using population based data.
University of Sydney Department of Ophthalmology (Centre for Vision Research), Eye Clinic, Westmead Hospital, Hawkesbury Road, Westmead, NSW 2145, Australia. paul_mitchell@wmi.usyd.edu.au
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Chua
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Mitchell
D000368:Aged; D000550:Amblyopia / Q000150:complications* / Q000453:epidemiology; D001315:Australia / Q000453:epidemiology; D015331:Cohort Studies; D004522:Educational Status; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009790:Occupations; D012307:Risk Factors; D014792:Visual Acuity / Q000502:physiology