[Liposarcoma of the extremities: recent developments in surgical therapy--analysis of 167 patients].
Liposarcoma is the second most common malignant soft-tissue tumor in adults. Between 1991 and 2002, 167 patients with extremity liposarcomas were treated in our center. Fifty tumors were classified as G1 liposarcomas (30%), 76 as G2 liposarcomas (45.5%), and 41 as G3 liposarcomas (24.5%). In 158 patients, (93.5%) wide tumor excision was performed. Major amputation was necessary in five patients. After a median follow-up of 36 months, 37 patients had developed local recurrence. The 5-year overall survival rate was 79%. The 5-year survival rate in primary tumors was 71/79 (90%, P<0.05) whereas 61/88 of recurrences relapsed locally (69%, P<0.05). Multidisciplinary cooperation in a tumor board is a precondition for adequate treatment.
Universitätsklinik für Plastische Chirurgie und Schwerbrandverletzte, Operatives Referenzzentrum für Gliedmassentumoren, Handchirurgiezentrum, BG-Kliniken Bergmannsheil Bochum, Ruhr-Universität Bochum. marcus.lehnhardt@rub.de
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M
Lehnhardt
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Kuhnen
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Drücke
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HH
Homann
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Joneidi Jafari
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HU
Steinau
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000671:Amputation, Surgical; D003131:Combined Modality Therapy; D005121:Extremities / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005858:Germany; D006801:Humans; D008080:Liposarcoma / Q000175:diagnosis / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery; D012086:Reoperation; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D015996:Survival Rate