Combinatorial synthesis in micro reactors.
This article reviews the current and future applications of micro reactors in the field of combinatorial chemistry and drug discovery. Liquid phase reactions have been used to illustrate the advantages of performing chemical reactions in micro reactors which illustrate that reactions can be performed very rapidly in high yield to enable the preparation of combinatorial libraries of structurally related compounds.
Department of Chemistry, University of Hull, Cottingham Road, Hull, HU6 7RX, UK. P.Watts@hull.ac.uk
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Watts
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Haswell
D020650:Combinatorial Chemistry Techniques; D015195:Drug Design; D036103:Nanotechnology; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis; D013329:Structure-Activity Relationship
D004364:Pharmaceutical Preparations