[Indium 111-labeled antibodies in the detection of colorectal carcinoma].
The aim of the study is detection of the recurrences and metastases of colorectal carcinomas using (111)In labelled antibodies B72.3 in 14 patients. With tomography, we can access better distinction of tumour in comparison to other structures and estimation of its size. Other imaging methods (CT, US) have advantage in detection of liver metastases, while immunoscintigraphy is more specific for the assessment of malignant abdominal tumours and extrahepatic metastases. The first results point out that Oncoscint CR-103 can be useful in diagnosis of recurrences and metastases of colorectal carcinoma, viability assessment after radiotherapy and in the choice of the adequate surgical treatment in dependence of the spread of the disease.
Artiko
V
V
Institut za nuklearnu medicinu, KCS, Beograd.
Obradović
V
V
Davidović
B
B
Petrović
N
N
Petrović
M
M
Krivokapić
Z
Z
Pavlov
M
M
Adanja
G
G
Sobić
D
D
Vlajković
M
M
Pavlović
S
S
Rebić
R
R
D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000556:secondary; D000911:Antibodies, Monoclonal; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000556:secondary; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D007205:Indium Radioisotopes; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging; D009842:Oligopeptides; D004369:Pentetic Acid / Q000031:analogs & derivatives*; D016719:Radioimmunodetection
D000911:Antibodies, Monoclonal; C063430:Indium 111In-satumomab pendetide; D007205:Indium Radioisotopes; D009842:Oligopeptides; D004369:Pentetic Acid