Drug susceptibility and genetic evaluation of Plasmodium falciparum isolates obtained in four distinct geographical regions of Kenya.
The drug resistance profiles of Plasmodium falciparum isolated from four regions in Kenya were analyzed for drug resistance profiles. We observed variability in resistance to a broad range of antimalarial drugs across Kenya as determined from in vitro drug susceptibility screening and genotyping analysis.
U.S. Army Medical Research Unit, Nairobi, Kenya.
Abigael
A
Mbaisi
Pamela
P
Liyala
Fredrick
F
Eyase
Rachel
R
Achilla
Hosea
H
Akala
Julia
J
Wangui
Josphat
J
Mwangi
Finnley
F
Osuna
Uzma
U
Alam
Bonnie L
BL
Smoak
Jon M
JM
Davis
Dennis E
DE
Kyle
Rodney L
RL
Coldren
Carl
C
Mason
Norman C
NC
Waters
D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D004351:Drug Resistance; D017125:Genes, Protozoan / Q000235:genetics; D005838:Genotype; D006801:Humans; D007630:Kenya / Q000453:epidemiology; D016778:Malaria, Falciparum / Q000453:epidemiology / Q000469:parasitology*; D017720:Molecular Epidemiology; D009154:Mutation / Q000235:genetics; D017891:Pharmacoepidemiology; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000235:genetics*
D000962:Antimalarials