Soluble intercellular adhesion molecule-1 (sICAM-1): an overview.
Soluble intercellular adhesion molecule-1 (sICAM-1) represents a circulating form of ICAM-1 that is constitutively expressed or is inducible on the cell surface of different cell lines. It serves as a counter-receptor for the lymphocyte function-associated antigen (LFA-1). Interaction between ICAM-1, present on endothelial cells, and LFA-1 facilitates leukocyte adhesion and migration across the endothelium. ICAM-1 and its circulating form have been implicated in the development of any number of diseases.
Witkowska
Anna Maria
AM
Department of Food Commodities Science and Technology, Medical Academy, Białystok, Poland.
Borawska
Maria Halina
MH
D000818:Animals; D001161:Arteriosclerosis / Q000276:immunology; D001327:Autoimmune Diseases / Q000276:immunology; D002448:Cell Adhesion / Q000276:immunology; D002465:Cell Movement / Q000276:immunology*; D016207:Cytokines / Q000276:immunology; D042783:Endothelial Cells / Q000276:immunology*; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000276:immunology*; D007962:Leukocytes / Q000276:immunology*; D016169:Lymphocyte Function-Associated Antigen-1 / Q000276:immunology*; D009369:Neoplasms / Q000276:immunology; D014777:Virus Diseases / Q000276:immunology
D016207:Cytokines; D016169:Lymphocyte Function-Associated Antigen-1; D018799:Intercellular Adhesion Molecule-1