Development of tyrosinase labile protecting groups for amines.
[reaction: see text] The development of two novel protecting groups for amines is described. Thus, a range of amines have been converted to ureas, and the deprotection of these upon exposure to mushroom tyrosinase (E.C. 1.14.18.1) has been demonstrated.
School of Chemistry, University of Reading, Whiteknights, Reading, RG6 6AD, UK. h.m.i.osborn@rdg.ac.uk
Helen M I
HM
Osborn
Nana Aba O
NA
Williams
D000363:Agaricales / Q000201:enzymology*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D014442:Monophenol Monooxygenase / Q000378:metabolism*; D014508:Urea / Q000737:chemistry*
D000588:Amines; D014508:Urea; D014442:Monophenol Monooxygenase