[The viral and bacterial nature of dysplasia and of cervical carcinoma].
The role of the infection component in etiopathogenesis of dysphasia and cervical carcinoma as well as optimization of their diagnosis and treatment schemes are discussed in the paper. On the basis of published data and authors' independent examinations, a tense relationship between the presence of dysphasia and cervical carcinoma, on the one hand, and sexually-transmitted genital infection and/or bacterial vaginosis present in the medial history, on the other hand, was verified. An intensity of vagina-microflora dysbacteriosis in genital clamidiosis and in dysphasia of cervical carcinoma as observed in women as well as an evaluation of immunoglobulins' levels in vaginal secretions can be a prognosticating criteria for a conducted treatment. A high efficiency and feasibility were shown of adding the recombinant alpha2-interferon to the combined treatment of genital clamidiosis and to preventing it from being chronic as well as to correcting the dysplastic impairments an to preventing the malignant neoplasms in the neck of uterus.
Afanas'ev
M S
MS
Aleshkin
V A
VA
Afanas'ev
S S
SS
Levakov
S A
SA
Vorob'ev
A A
AA
Sidorova
I S
IS
Nesvizhskiĭ
Iu V
IuV
D000970:Antineoplastic Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002690:Chlamydia Infections / Q000150:complications / Q000276:immunology; D005260:Female; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use; D002578:Uterine Cervical Dysplasia / Q000188:drug therapy / Q000382:microbiology* / Q000821:virology; D002583:Uterine Cervical Neoplasms / Q000382:microbiology* / Q000517:prevention & control / Q000821:virology; D014621:Vagina / Q000382:microbiology
D000970:Antineoplastic Agents; D000998:Antiviral Agents; D016898:Interferon-alpha