Weight loss without losing muscle mass in pre-obese and obese subjects induced by a high-soy-protein diet.
OBJECTIVE
To determine change of weight, body composition, metabolic and hormonal parameters induced by different intervention protocols.


METHODS
Randomized, controlled study including participants exhibiting a BMI between 27.5 and 35. Three different interventions containing lifestyle education (LE-G), or a substitutional diet containing a high-soy-protein low-fat diet with (SD/PA-G) or without (SD-G) a guided physical activity program.


METHODS
A total of 90 subjects (mean weight 89.9 kg; mean BMI 31.5), randomly assigned to one of three treatment groups.


METHODS
Change in body weight, fat mass and lean body mass measured with the Bod Pod device at baseline, 6 weeks and 6 months; change in metabolic and hormonal parameters.


RESULTS
In all, 83 subjects completed the 6-months study. BMI dropped highly significantly in all groups (LE-G: -2.2+/-1.43 kg/m(2); SD-G: -3.1+/-1.29 kg/m(2); SD/PA-G: -3.0+/-1.29 kg/m(2)). Subjects in the SD-G and in the SD/PA-G lost more weight during the 6-months study (-8.9+/-3.9; -8.9+/-3.9 kg) than did those in the LE-G (-6.2+/-4.2 kg), and had a greater decrease in fat mass (-8.8+/-4.27; -9.4+/-4.54 kg) than those in the LE-G (-6.6+/-4.59 kg). In contrast, no significant intraindividual or between-group changes in the fat-free mass were seen. In all groups, metabolic parameters showed an improvement in glycemic control and lipid profile.


CONCLUSIONS
Our data suggest that a high-soy-protein and low-fat diet can improve the body composition in overweight and obese people, losing fat but preserving muscle mass.
Deibert
P
P
Department of Rehabilitative and Preventive Sports Medicine, University Hospital, D-79106 Freiburg, Germany. deibert@msm1.ukl.uni-freiburg.de
König
D
D
Schmidt-Trucksaess
A
A
Zaenker
K S
KS
Frey
I
I
Landmann
U
U
Berg
A
A
D001823:Body Composition; D015992:Body Mass Index; D018752:Diet, Fat-Restricted; D004038:Diet, Reducing; D004044:Dietary Proteins / Q000008:administration & dosage*; D015444:Exercise; D005260:Female; D006801:Humans; D008019:Life Style; D008055:Lipids / Q000097:blood; D008297:Male; D009132:Muscles / Q000473:pathology; D009765:Obesity / Q000178:diet therapy* / Q000503:physiopathology / Q000628:therapy; D010353:Patient Education as Topic / Q000379:methods; D030262:Soybean Proteins / Q000008:administration & dosage*; D015431:Weight Loss
D004044:Dietary Proteins; D008055:Lipids; D030262:Soybean Proteins