Nocturnal enuresis: medical management.
Nocturnal enuresis is a problem that affects many children and their families. The etiology seems to be multifactorial and may include a combination of genetic factors,abnormal urodynamics, alterations in vasopressin secretion, sleep factors, psychologic factors, organic disease, and maturational delay. Generally, a complete history and physical examination, with a specific focus on the genitourinary, gastrointestinal, and neurologic systems, is all is that is needed in the evaluation of a patient with enuresis.Currently, the mainstays of medical therapy are DDAVP, imipramine, and oxybutynin. Medications can help to control the symptoms of enuresis, but they generally do not provide a cure; therefore, behavioral therapy is often recommended in conjunction with pharmacotherapy.
Mammen
Anju A
AA
Department of Urology, University of Connecticut and Connecticut Children's Medical Center, 282 Washington Street, Suite 2G, Hartford, CT 06106, USA.
Ferrer
Fernando A
FA
D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use; D004775:Enuresis / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use; D008333:Mandelic Acids / Q000627:therapeutic use; D010808:Physical Examination; D012076:Renal Agents / Q000627:therapeutic use; D014563:Urodynamics
D000929:Antidepressive Agents, Tricyclic; D008333:Mandelic Acids; D012076:Renal Agents; D003894:Deamino Arginine Vasopressin; C005419:oxybutynin; D007099:Imipramine