Myocardial ischemia due to severe amoxicillin allergy.
A patient suffered a myocardial injury as a manifestation of anaphylactic reaction to amoxicillin-clavulanic acid administration. A cardiologic study (ergometry and catheterization) showed no obstructive coronary disease and prick test to amoxicillin was positive. Anaphylaxis may cause myocardial injury and the mechanism is likely to be vasospasm induced by mast cells and basophil mediators.
López-Abad
R
R
Allergy Section, Hospital Universitario Marqués de Valdecilla, Santander, Spain. mabadl@terra.es
Rodríguez
F
F
García-Abujeta
J L
JL
Martín-Gil
D
D
Jerez
J
J
D000328:Adult; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000009:adverse effects* / Q000276:immunology; D000707:Anaphylaxis / Q000139:chemically induced* / Q000150:complications* / Q000276:immunology; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000276:immunology; D004342:Drug Hypersensitivity / Q000150:complications* / Q000209:etiology* / Q000276:immunology; D006801:Humans; D008297:Male; D017202:Myocardial Ischemia / Q000139:chemically induced* / Q000276:immunology
D000900:Anti-Bacterial Agents; D019980:Amoxicillin-Potassium Clavulanate Combination