Jasmonic acid prevents the accumulation of cyclin B1;1 and CDK-B in synchronized tobacco BY-2 cells.
Jasmonic acid (JA) plays a crucial role in plant fertility and defense responses. It exerts an inhibitory effect on plant growth when applied exogenously. This effect seems to be somehow related to a negative regulation of cell cycle progression in the meristematic tissues. In this report, we focus on the molecular events that occur during JA-induced G2 arrest. We demonstrate that JA prevents the accumulation of B-type cyclin-dependent kinases and the expression of cyclin B1;1, which are both essential for the initiation of mitosis. This feature suggests the existence of an early G2 checkpoint that is affected by JA.
Swiatek
Agnieszka
A
Laboratory of Plant Biochemistry and Physiology, Department of Biology, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.
Azmi
Abdelkrim
A
Stals
Hilde
H
Inzé
Dirk
D
Van Onckelen
Harry
H
D016590:Aphidicolin / Q000378:metabolism; D002453:Cell Cycle / Q000187:drug effects*; D002460:Cell Line; D019926:Cyclin B / Q000187:drug effects / Q000378:metabolism*; D056744:Cyclin B1; D018844:Cyclin-Dependent Kinases / Q000187:drug effects / Q000378:metabolism*; D003517:Cyclopentanes / Q000494:pharmacology*; D007700:Kinetics; D054883:Oxylipins; D010937:Plant Growth Regulators / Q000494:pharmacology; D014026:Nicotiana / Q000737:chemistry* / Q000187:drug effects / Q000201:enzymology
D019926:Cyclin B; D056744:Cyclin B1; D003517:Cyclopentanes; D054883:Oxylipins; D010937:Plant Growth Regulators; D016590:Aphidicolin; C011006:jasmonic acid; D018844:Cyclin-Dependent Kinases