Human metapneumovirus and severity of respiratory syncytial virus disease.
We screened 23 children with severe respiratory syncytial virus (RSV) disease and 23 children with mild RSV disease for human metapneumovirus (HMPV). Although HMPV was circulating in Connecticut, none of the 46 RSV-infected patients tested positive for HMPV. In our study population, HMPV did not contribute to the severity of RSV disease.
Yale University School of Medicine, New Haven, Connecticut 06520-8064, USA.
Isaac
I
Lazar
Carla
C
Weibel
James
J
Dziura
David
D
Ferguson
Marie L
ML
Landry
Jeffrey S
JS
Kahn
D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases; D029121:Metapneumovirus / Q000302:isolation & purification / Q000472:pathogenicity*; D018184:Paramyxoviridae Infections / Q000150:complications*; D018357:Respiratory Syncytial Virus Infections / Q000150:complications / Q000503:physiopathology*; D018113:Respiratory Syncytial Virus, Human / Q000472:pathogenicity*; D012720:Severity of Illness Index