[Otologic signs and symptoms as first manifestations of Wegener's granulomatosis with very severe clinical course--review of the literature and case report].
A case of Wegener's granulomatosis in female aged 47 is described. Otological symptoms and signs connected with middle ear inflammation and masked mastoiditis about two months outstriped other signs particular from lower respiratory tract. The patient was surgically treated--antromastoidectomy was performed. After few days rapid worsening of patient's general state followed with hectic fever and inflammatory pulmonary changes. The patient was next treated in the Clinic of Pulmonary Diseases and Tuberculosis where the diagnosis of Wegener's granulomatosis was established on the basis of immunological findings (antibodies c-ANCA and PR3). The patient is treated from 9 months with cyclophosphamide and prednisone with improvement. The inability of ENT-surgeon in proper diagnosis and treatment in initial stage of the disease is stressed.
Oddział Otolaryngologiczny Szpitala Miejskiego im. J. Brudzińskiego w Gdyni.
Józef
J
Jordanl
Alicja
A
Siemińska
Jerzy
J
Kuczkowski
Jarosław
J
Sova
D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D008171:Lung Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D008875:Middle Aged; D010033:Otitis Media / Q000000981:diagnostic imaging / Q000209:etiology*; D011859:Radiography; D016896:Treatment Outcome