Effects of alcohol and cigarette consumption on human seminal quality.
OBJECTIVE
To evaluate the effects of alcohol or cigarette consumption on seminal parameters in a large population of men attending an andrology laboratory.


METHODS
Analysis of ten years of data (1990-1999).


METHODS
Andrology and Reproduction Laboratory (Córdoba, Argentina).


METHODS
Patients (3,976) were grouped according to nonsmokers; <==20 cigarettes/day; >20 cigarettes/day; nonalcohol consumers; <==500 mL of wine ( approximately 52 g of ethanol) or equivalent/day; and >500 mL of wine or equivalent/day. Patients who drank alcohol and smoked were also considered.


METHODS
A questionnaire was voluntarily filled out by patients. It provided data on drug consumption and genitourinary diseases.


METHODS
Seminal volume, sperm concentration, motility, viability, and morphology.


RESULTS
No statistical differences in seminal parameters were found between the degrees of alcohol or tobacco consumption; so, independently of the degree of consumption patients were considered as smokers or alcohol consumers.


CONCLUSIONS
Alcohol or cigarette consumption did not alter the seminal parameters. Nevertheless, when the patients with these two habits were compared to those without these habits, a significant reduction in seminal volume, sperm concentration, percentage of motile spermatozoa, and a significant increase of the nonmotile viable gametes were detected. The synergic or additive effect of these two toxic habits is discussed.
Instituto de Fisiología, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Ana Carolina
AC
Martini
Rosa Inés
RI
Molina
Daniel
D
Estofán
Daniel
D
Senestrari
Marta
M
Fiol de Cuneo
Rubén Daniel
RD
Ruiz
D000328:Adult; D000428:Alcohol Drinking; D001118:Argentina; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012661:Semen / Q000737:chemistry / Q000502:physiology*; D012907:Smoking; D013076:Sperm Count; D013081:Sperm Motility / Q000502:physiology*; D011795:Surveys and Questionnaires