Use of "tethering" for the identification of a small molecule that binds to a dynamic hot spot on the interleukin-2 surface.
Berg
Thorsten
T
Max Planck Institute of Biochemistry, Department of Molecular Biology, Am Klopferspitz 18, 82152 Martinsried, Germany. berg@biochem.mpg.de
D001665:Binding Sites; D018360:Crystallography, X-Ray; D007376:Interleukin-2 / Q000737:chemistry / Q000378:metabolism*; D008958:Models, Molecular
D007376:Interleukin-2