[Research progress of adipose tissue-derived stromal cells].
OBJECTIVE
To review research progress of adipose tissue-derived stromal cells (ADSCs).


METHODS
The recent articles on ADSCs were extensively reviewed, and the culture and differentiation ability of ADSCs were investigated.


RESULTS
A population of stem cells could be isolated from adult adipose tissue, they were processed to obtain a fibroblast-like population of cells and could be maintained in vitro for extended periods with stable population doubling. The majority of the isolated cells were mesenchymal origin, with a few pericytes, endothelial cells and smooth muscle cells. ADSCs could be induced to differentiate into multiple mesenchymal cell types, including osteogenic, chondrogenic, myogenic and adipogenic cells, they could also differentiate into nerve cells.


CONCLUSIONS
ADSCs can substitute mesenchymal stem cells and become an alternative stem cells source for tissue engineering.
Department of Neurosurgery, Chaozhou Central Hospital, Chaozhou Guangdong, 521021, PR China.
Liye
L
Yang
Jiakun
J
Zheng
Guozhen
G
Hui
D000273:Adipose Tissue / Q000166:cytology*; D000818:Animals; D002454:Cell Differentiation; D002478:Cells, Cultured; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology; D013234:Stem Cells / Q000166:cytology*; D017154:Stromal Cells / Q000166:cytology*; D023822:Tissue Engineering