Impact of diabetes mellitus type 2 on in-hospital outcome after cardiac catheterizations in a large cohort of octogenarians.
OBJECTIVE
To assess the impact of diabetes mellitus type 2 (DM) in 1085 octogenarians on in-hospital outcome after cardiac catheterization (CATH) and/or percutaneous coronary intervention (PCI).


RESULTS
We studied 1085 consecutive octogenarians [82.6+/-2.6 years; 401 DM, 684 without DM (non-DM)]. Age, acute myocardial infarctions (DM: 26%, non-DM: 21%) and extent of disease (three-vessel disease, DM: 34%, non-DM: 31%) were similar in both groups. There was a similar percentage of interventions (PCI: DM: 30% vs. non-DM: 29%; bypass surgery: DM: 30% vs. non-DM: 25%) performed in both groups. Thirty-one patients (2.9%) died during hospital stay (DM: 2.2%; non-DM: 3.2%; p=0.46) of whom 16 died (DM: 1.0%; non-DM: 1.9%) during (n=4) or after (n=12) interventions in patients who were already admitted in cardiogenic shock. At the puncture site, 87 complications occurred (DM 6.5% vs. non-DM 6.4%, p=0.87). Stepwise logistic regression analyses identified DM as an independent predictor of adverse events during CATH, but not PCI. Furthermore, DM was not a predictor for vascular complications.


CONCLUSIONS
Catheterization-related complication rates are different in diabetic as compared to nondiabetic patients during CATH, but not PCI. Octogenarians should be granted access to an invasive treatment strategy even in the presence of DM.
Department of Internal Medicine and Cardiology, University of Leipzig-Heart Center, Strümpellstr. 39, 04289 Leipzig, Germany. j.niebauer@medizin.uni-leipzig.de
Josef
J
Niebauer
Sebastian
S
Sixt
Fuchun
F
Zhang
Jiangtao
J
Yu
Peter
P
Sick
Holger
H
Thiele
Bernward
B
Lauer
Gerhard
G
Schuler
D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D006328:Cardiac Catheterization / Q000009:adverse effects*; D016022:Case-Control Studies; D015331:Cohort Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D006331:Heart Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D011859:Radiography; D018570:Risk Assessment; D016896:Treatment Outcome; D014652:Vascular Diseases / Q000209:etiology* / Q000401:mortality