[The clinical study of water loading in gastric sensation thresholds testing].
OBJECTIVE
To establish a simple, noninvasive, physiologic diagnostic assay for evaluating gastric sensation thresholds.


METHODS
The gastric perception and discomfort thresholds were monitored in 15 healthy controls and 30 functional dyspepsia patients by water load test and gastric barostat. Based on barostat the sensitivity, specificity, Kappa value, coincidence rate of water load test were evaluated and the correlation between those two methods was assessed.


RESULTS
Compared with gastric barostat, the sensitivity, specificity, Kappa value and coincidence rate of water load test for evaluating perception thresholds were reached 85.7%, 93.5%, 0.82, and 91.1%. These of water load test for evaluating discomfort thresholds were reached 81.8%, 91.2%, 0.79, and 88.9% compared with gastric barostat. The results were showed a good correlation between water load test and gastric barostat (P < 0.01, respectively).


CONCLUSIONS
It had higher specificity, Kappa value and coincidence rate of water load test for evaluating the sensation threshold compared with gastric barostat. It can be applied effectively in clinical diagnosis for evaluating the sensory threshold.
Division of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Technology and Science, Wuhan 430022, China.
Qi-xiang
QX
Li
Liang-ru
LR
Zhu
Xiao-hua
XH
Hou
D000328:Adult; D003938:Diagnostic Techniques, Digestive System; D004326:Drinking; D004415:Dyspepsia / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D012680:Sensitivity and Specificity; D012684:Sensory Thresholds; D013270:Stomach / Q000502:physiology* / Q000503:physiopathology