Optimization of analysis of skeletal ossification of laboratory animals by means of digital radiography software options.
Digital radiography software enables image manipulation and reformatting, thus allowing precise diagnosis and measurements even in cases when exposure parameters are suboptimum and visualized structures are faintly radiopaque. The aim of the paper is evaluation of digital radiography software options in optimization of analysis of skeletal ossification in rats. Wistar at pups at the age 0 to 22 days of postnatal life were radiographed by means of a storage phosphor digital radiography system. In order to optimize viewing conditions as well as density nd linear measurements all available image reformatting options and filters of digital radiography software Digora 2.0 were used and evaluated. Application of digital radiography image enhancement options was found advantageous in optimization and improvement of viewing conditions and it allowed higher accuracy and reproducibility of the measurements. Digital radiography is a novel and precise tool in determination of skeleton ossification and could be used as a supplement to routine staining methods.
Rózyło-Kalinowska
Ingrid
I
2nd Department of Radiology, Medical University of Lublin.
Michalska
Anna
A
Burdan
Franciszek
F
D000818:Animals; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D010012:Osteogenesis; D011856:Radiographic Image Enhancement / Q000379:methods*; D051381:Rats; D017208:Rats, Wistar; D012680:Sensitivity and Specificity