A case of prolonged seizure activity after combined use of bupropion and clomipramine.
A case is reported of seizure development after combined use of bupropion and clomipramine. Electroencephalography revealed frequent generalized spike and wave complexes prominent on both frontal areas. These newly developed epileptiform discharges persisted even after discontinuation of both drugs.
Department of Psychiatry, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Yong-Wook
YW
Shin
Tae Moon
TM
Erm
Eun Jung
EJ
Choi
Seong Yoon
SY
Kim
D000328:Adult; D000928:Antidepressive Agents / Q000009:adverse effects*; D016642:Bupropion / Q000009:adverse effects*; D002997:Clomipramine / Q000009:adverse effects*; D004359:Drug Therapy, Combination; D004569:Electroencephalography / Q000187:drug effects / Q000379:methods; D005260:Female; D006801:Humans; D012559:Schizophrenia / Q000188:drug therapy; D012640:Seizures / Q000209:etiology*
D000928:Antidepressive Agents; D016642:Bupropion; D002997:Clomipramine