Hiponatremia during pregnancy with adriamycin-induced nephrotic syndrome in rats.
The purpose of the studies was to assess the electrolyte concentration in blood serum of pregnant Wistar rats, in which pregnancy coexisted with adriamycin-induced nephrotic syndrome. The results displayed hiponatremia in serum blood of these female rats. After puerperium sodium concentration came to the level similar to that before pregnancy, in comparison to control. Hiponatremia could cause neurological complications, which in pregnancy could activate eclampsia.
Department and Institute of Histology and Embryology with the Laboratory for Experimental Cytology, Medical University of Lublin.
Agnieszka
A
Pedrycz
Krystyna
K
Czerny
Marcin
M
Wieczorski
Daria
D
Hernik
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects*; D004317:Doxorubicin / Q000009:adverse effects*; D004461:Eclampsia / Q000209:etiology; D005260:Female; D007010:Hyponatremia / Q000097:blood*; D009404:Nephrotic Syndrome / Q000097:blood* / Q000139:chemically induced; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood* / Q000209:etiology; D051381:Rats; D017208:Rats, Wistar; D012964:Sodium / Q000097:blood*; D013997:Time Factors
D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin; D012964:Sodium