[Treatment of 40 patients with primary tracheal carcinoma].
OBJECTIVE
To study the efficacy of treatment in 40 patients with primary tracheal carcinoma.


METHODS
From 1970 to 2001, 40 patients with primary tracheal carcinoma treated in our hospital were retrospectively reviewed. Twenty-eight were male and 12 were female with median age of 47 years. The median interval from onset of symptoms to diagnosis was 10 months (1 - 60 months). Fifteen patients had adenoid cystic carcinoma, 14 squamous cell carcinoma, 8 adenocarcinoma, 2 small-cell carcinoma and 1 mucoepidermoid carcinoma. Thirty-two patients received operation plus adjuvant radiotherapy, 6 received radiotherapy alone and 2 received operation alone.


RESULTS
The median survival time for all patients was 40 months. The 1-, 5-, and 10-year survival rate was 86%, 59% and 29%, respectively. The 1-, 5-, and 10-year local control rate was 84%, 60% and 50%, respectively. Distant metastasis rate in 1, 5, and 10 years was 17%, 51% and 84%, respectively.


CONCLUSIONS
Surgical resection plus adjuvant radiotherapy is a reasonable mode of treatment. Despite late local recurrence after initial treatment, its intrinsic feature, excellent long-term palliation can be achieved after treatment.
Wu
Kai-liang
KL
Department of Radiation Oncology, Cancer Hospital, Fudan University, Shanghai 200032, China. kailiangwu@citiz.net
Jiang
Guo-liang
GL
Fu
Xiao-long
XL
Zhou
Yun-zhong
YZ
D000328:Adult; D000368:Aged; D003037:Cobalt Radioisotopes; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010315:Particle Accelerators; D018714:Radiotherapy, Adjuvant; D015996:Survival Rate; D014134:Tracheal Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D014140:Tracheotomy / Q000379:methods*
D003037:Cobalt Radioisotopes