Efficient and regiospecific one-pot synthesis of substituted 1,2,4-triazoles.
An efficient one-pot, three-component synthesis of substituted 1,2,4-triazoles has been developed, utilizing a wide range of substituted primary amines and acyl hydrazides.
Department of Medicinal Chemistry, AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, Leics LE11 5RH, United Kingdom. mike.stocks@astrazeneca.com
Michael J
MJ
Stocks
David R
DR
Cheshire
Rachel
R
Reynolds
D020650:Combinatorial Chemistry Techniques; D007202:Indicators and Reagents; D015394:Molecular Structure; D013237:Stereoisomerism; D014230:Triazoles / Q000138:chemical synthesis*
D007202:Indicators and Reagents; D014230:Triazoles; C045575:1,2,4-triazole