Highly chemoselective 2,4,5-triaryl-1,3-dioxolane formation from intermolecular 1,3-dipolar addition of carbonyl ylide with aryl aldehydes.
[reaction: see text] Rhodium(II) acetate catalyzed 1,3-dipolar cycloaddition of methyl phenyldiazoacetate with a mixture of electron-rich and electron-deficient aryl aldehydes gave 1,3-dioxolanes in high yield with excellent chemoselectivity.
Key Laboratory for Asymmetric Synthesis and Chirotechnology of Sichuan Province, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041 & Graduate School of the Chinese Academy of Sciences, Beijing, China.
Chong-Dao
CD
Lu
Zhi-Yong
ZY
Chen
Hui
H
Liu
Wen-Hao
WH
Hu
Ai-Qiao
AQ
Mi