Highly diastereoselective Prins-type cyclisation of cyclopropylvinylic aldehydes mediated by TiCl4.
A novel intramolecular Prins type cyclisation of cyclopropylvinylic aldehydes promoted by TiCl(4) under mild reaction conditions to form cis-cyclic products in high yields has been accomplished.
Department of Chemistry and Lab for Metal-Catalysed Reactions, Sungkyunkwan University, Suwon 440-746, Korea. cmyu@chem.skku.ac.kr
Chan-Mo
CM
Yu
Seok-Keun
SK
Yoon
Young-Taek
YT
Hong
Jimin
J
Kim