Optimization of an accelerator-based epithermal neutron source for neutron capture therapy.
A modeling investigation was performed to choose moderator material and size for creating optimal epithermal neutron beams for BNCT based on a proton accelerator and the (7)Li(p,n)(7)Be reaction as a neutrons source. An optimal configuration is suggested for the beam shaping assembly made from polytetrafluoroethylene and magnesium fluorine to be placed on high current IPPE proton accelerator KG-2.5. Results of calculation were experimentally tested and are in good agreement with measurements.
Kononov
O E
OE
State Scientific Center of Russian Federation, Institute for Physics and Power Engineering, Bondarenko sq. 1, 249033 Obninsk, Kaluga, Russia. kononov@ippe.ru
Kononov
V N
VN
Bokhovko
M V
MV
Korobeynikov
V V
VV
Soloviev
A N
AN
Sysoev
A S
AS
Gulidov
I A
IA
Chu
W T
WT
Nigg
D W
DW
D016754:Boron Neutron Capture Therapy / Q000295:instrumentation* / Q000706:statistics & numerical data; D003198:Computer Simulation; D005160:Facility Design and Construction; D005214:Fast Neutrons / Q000627:therapeutic use*; D006801:Humans; D009010:Monte Carlo Method; D009369:Neoplasms / Q000532:radiotherapy; D010315:Particle Accelerators; D019047:Phantoms, Imaging; D011879:Radiotherapy Dosage