The sweet and the bitter of mammalian taste.
The discovery of two families of mammalian taste receptors has provided important insights into taste recognition and taste perception. Recent studies have examined the receptors and signaling pathways that mediate sweet, bitter, and amino acid taste detection in mammals. These studies demonstrate that taste cells are selectively tuned to different taste modalities and clarify the logic of taste coding in the periphery.
Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California-Berkeley, 291 Life Sciences Addition, Berkeley, California 94720, USA. kscott@berkeley.edu
Kristin
K
Scott
D000818:Animals; D006801:Humans; D007527:Isoenzymes / Q000502:physiology; D008565:Membrane Proteins / Q000502:physiology; D009475:Neurons, Afferent / Q000166:cytology / Q000502:physiology*; D054799:Phospholipase C beta; D043562:Receptors, G-Protein-Coupled / Q000235:genetics; D015398:Signal Transduction / Q000235:genetics; D050053:TRPM Cation Channels; D013649:Taste / Q000502:physiology*; D013650:Taste Buds / Q000166:cytology / Q000502:physiology*; D010738:Type C Phospholipases / Q000502:physiology; D000098706:Taste Receptors, Type 2
D007527:Isoenzymes; D008565:Membrane Proteins; D043562:Receptors, G-Protein-Coupled; D050053:TRPM Cation Channels; C404409:TRPM5 protein, human; C431926:taste receptors, type 1; D000098706:Taste Receptors, Type 2; D010738:Type C Phospholipases; D054799:Phospholipase C beta