Nicorandil: a review of its use in the management of stable angina pectoris, including high-risk patients.
Nicorandil (Adancor, Angicor, Dancor, Nikoril [Europe], Ikorel [Europe and Oceania], Sigmart [Japan, Korea and Taiwan]) is an adenosine triphosphate (ATP)-sensitive potassium (KATP) channel agonist with nitrate-like properties used in the management of stable angina pectoris. With well established monotherapeutic antianginal activity and a beneficial effect (when added to optimal antianginal therapy) on clinical outcomes in high-risk patients with stable angina, twice-daily oral nicorandil is a useful alternative or addition to other antianginal therapy.
Adis International Limited, Auckland, New Zealand. demail@adis.co.nz
Dene
D
Simpson
Keri
K
Wellington
D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy*; D000818:Animals; D019540:Area Under Curve; D002986:Clinical Trials as Topic; D006801:Humans; D008875:Middle Aged; D020108:Nicorandil / Q000494:pharmacology* / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000494:pharmacology* / Q000627:therapeutic use*
D014665:Vasodilator Agents; D020108:Nicorandil