[Experimental study on effect of erzhi tiangui recipe on quality of oocyte in mice].
OBJECTIVE
To observe the effect of Erzhi Tiangui recipe (ETR) on quality of oocyte in the process of external fertilization and embryo-transplantation.


METHODS
Eighty mice were randomly divided into 4 groups, Group A treated with ETR plus human menopausal gonadotropin (HMG), Group B with ETR, Group C with HMG and Group D with normal saline. Ovulation test and cleavage test were conducted to observe the effect of treatment on quality of oocytes.


RESULTS
The difference on ovulation number between Group A and C was insignificant, but the difference in comparison between the two groups was significant in aspects of oocyte morphological scoring, fertilization rate and cleavage rate (P<0.05).


CONCLUSIONS
ETR could play its effect synergistically with Western medicine, and raise the quality of oocytes.
The Reproductive and Hereditary Center of the Affiliated Hospital of Shandong University of TCM, Jinan 250011. flian@chinaivf.com
Fang
F
Lian
Zheng-gao
ZG
Sun
Jian-wei
JW
Zhang
Ning
N
Zhang
Yanhe
Y
Liu
Lin
L
Mu
Peng
P
Zhang
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D004357:Drug Synergism; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004624:Embryo Transfer; D005260:Female; D005306:Fertilization / Q000187:drug effects; D005307:Fertilization in Vitro / Q000187:drug effects*; D008596:Menotropins / Q000494:pharmacology*; D051379:Mice; D009865:Oocytes / Q000187:drug effects* / Q000502:physiology; D010062:Ovulation Induction; D011897:Random Allocation
D004365:Drugs, Chinese Herbal; D008596:Menotropins