Effect of povidone iodine on silicone gel breast implants in vitro: implications for clinical practice.
Irrigation of breast implants and breast implant pockets with various solutions, including povidone iodine, has been a common practice among plastic surgeons for many years. Recent reports of potential weakening of silicone tubing have led the Food and Drug Administration to pronounce any contact of povidone iodine with breast implants a contraindication. An in vitro experimental study was undertaken to assess the effect of povidone iodine on the physical properties of silicone breast implant shells. Identical specimens were obtained from the shells of silicone breast implants according to published standards. The specimens were randomly assigned to eight groups of five and incubated in various solutions of decreasing concentration of povidone iodine (10% to 0.01%), and a control group (0.9% saline) was used. The containers were stored in a warming cabinet at 37 degrees C for 4 weeks. Testing of the specimens for tensile strength following 4 weeks of incubation showed no significant difference among any of the groups, including the control group. In addition, no correlation was shown between the concentration of the solution used and the tensile strength of the specimens.
Zambacos
George J
GJ
Department of Plastic and Reconstructive Surgery, Derriford Hospital, Plymouth, United Kingdom. gzamba@doctor.com
Nguyen
Dai
D
Morris
Robert J
RJ
D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D018427:Breast Implants / Q000382:microbiology; D003286:Contracture / Q000382:microbiology / Q000517:prevention & control*; D006801:Humans; D066298:In Vitro Techniques; D011206:Povidone-Iodine / Q000008:administration & dosage*; D016459:Prosthesis-Related Infections / Q000382:microbiology / Q000517:prevention & control; D020034:Silicone Gels; D013203:Staphylococcal Infections / Q000517:prevention & control; D013212:Staphylococcus epidermidis; D007507:Therapeutic Irrigation / Q000379:methods*
D000891:Anti-Infective Agents, Local; D020034:Silicone Gels; D011206:Povidone-Iodine