[Application of chi-square test and exact test in Hardy-Weinberg equilibrium testing].
This article review the application of chi-square test of various data handling methods and exact test in Hardy-Weinberg equilibrium testing of human genetic marker in population genetics. The importance of HWE-exact test in multiallelic system was emphasized, especially in the study of forensic VNTR and STR typing.
Faculty of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030,China. huangdaixin@hotmail.com
Dai-Xin
DX
Huang
Qing-En
QE
Yang
D000483:Alleles; D016009:Chi-Square Distribution; D005554:Forensic Medicine; D005787:Gene Frequency; D005828:Genetics, Population / Q000379:methods*; D005838:Genotype; D006801:Humans; D016013:Likelihood Functions; D008957:Models, Genetic; D015233:Models, Statistical