Preoperative chemotherapy as a predisposing factor for colonization of upper respiratory tract with Candida spp. in patients with non-small cell lung cancer.
In the present study 48 patients with non-small cell lung cancer (NSCLC) were included--20 patients from control group and 28 patients after at least one course of preoperative chemotherapy. The analysis of nasopharyngeal microflora in these patients suggests that preoperative chemotherapy can be regarded as a predisposing factor for colonization of mucous membrane of throat with yeast-like fungi--Candida spp.
Department of Thoracic Surgery, Medical University of Lublin.
Franciszek
F
Furmanik
Paweł
P
Rybojad
Anna
A
Kasprzycka
Izabela
I
Korona-Głowniak
Anna
A
Malm
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D002175:Candida / Q000302:isolation & purification*; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy* / Q000601:surgery; D017024:Chemotherapy, Adjuvant / Q000009:adverse effects; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009305:Nasopharynx / Q000382:microbiology; D020360:Neoadjuvant Therapy / Q000009:adverse effects* / Q000379:methods; D012137:Respiratory System / Q000382:microbiology*; D016896:Treatment Outcome