[Experimental study on effect of erzhi tiangui recipe on quality of oocyte in mice].
OBJECTIVE
To observe the effect of Erzhi Tiangui recipe (ETR) on quality of oocyte in the process of external fertilization and embryo-transplantation.


METHODS
Eighty mice were randomly divided into 4 groups, Group A treated with ETR plus human menopausal gonadotropin (HMG), Group B with ETR, Group C with HMG and Group D with normal saline. Ovulation test and cleavage test were conducted to observe the effect of treatment on quality of oocytes.


RESULTS
The difference on ovulation number between Group A and C was insignificant, but the difference in comparison between the two groups was significant in aspects of oocyte morphological scoring, fertilization rate and cleavage rate (P<0.05).


CONCLUSIONS
ETR could play its effect synergistically with Western medicine, and raise the quality of oocytes.
Lian
Fang
F
The Reproductive and Hereditary Center of the Affiliated Hospital of Shandong University of TCM, Jinan 250011. flian@chinaivf.com
Sun
Zheng-gao
ZG
Zhang
Jian-wei
JW
Zhang
Ning
N
Liu
Yanhe
Y
Mu
Lin
L
Zhang
Peng
P
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D004357:Drug Synergism; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004624:Embryo Transfer; D005260:Female; D005306:Fertilization / Q000187:drug effects; D005307:Fertilization in Vitro / Q000187:drug effects*; D008596:Menotropins / Q000494:pharmacology*; D051379:Mice; D009865:Oocytes / Q000187:drug effects* / Q000502:physiology; D010062:Ovulation Induction; D011897:Random Allocation
D004365:Drugs, Chinese Herbal; D008596:Menotropins