Polytriazoles as copper(I)-stabilizing ligands in catalysis.
Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes. The C3-symmetric derivative, TBTA, was shown to be a powerful stabilizing ligand for copper(I), protecting it from oxidation and disproportionation, while enhancing its catalytic activity.
Chan
Timothy R
TR
Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, USA.
Hilgraf
Robert
R
Sharpless
K Barry
KB
Fokin
Valery V
VV
D000588:Amines / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011108:Polymers / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry*
D000588:Amines; D008024:Ligands; D011108:Polymers; D014230:Triazoles; D003300:Copper