Coordinated expression of MUC2 and CDX-2 in mucinous carcinomas of the lung can be explained by the role of CDX-2 as transcriptional regulator of MUC2.
Mesquita
Patrícia
P
Almeida
Raquel
R
Van Seuningen
Isabelle
I
David
Leonor
L
D002288:Adenocarcinoma, Mucinous / Q000235:genetics / Q000378:metabolism*; D000071616:CDX2 Transcription Factor; D018398:Homeodomain Proteins / Q000096:biosynthesis* / Q000502:physiology; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics / Q000378:metabolism*; D055262:Mucin-2; D009077:Mucins / Q000096:biosynthesis* / Q000235:genetics; D015534:Trans-Activators; D014158:Transcription, Genetic
D000071616:CDX2 Transcription Factor; D018398:Homeodomain Proteins; C524625:MUC2 protein, human; D055262:Mucin-2; D009077:Mucins; D015534:Trans-Activators