[Eyelid and cutaneous lesions as the sole indicators of tuberous sclerosis].
METHODS
A 53-year old woman presented a tuberous sclerosis complex (Bourneville's disease) characterised by facial cutaneous angiofibromas, periungual fibromas and cutaneous leaf-shaped macules in the thorax. She also presented two neoplasms in the left lower eyelid which were histopathologically diagnosed as angiofibromas. There were no other ophthalmologic or systemic findings.


CONCLUSIONS
Tuberous sclerosis complex is an autosomical dominant neurocutaneous phakomatosis in which up to 80% of cases represent new mutations, characterized by mental retardation, epilepsy and angiofibromas. Incidence is very low and ophthalmic presentation with isolated cutaneous angiofibromas is most unusual.
Mencía-Gutiérrez
E
E
Hospital 12 de Octubre, Universidad Complutense de Madrid, Spain. emencia.hdoc@salud.madrid.org
Gutiérrez-Díaz
E
E
Ricoy
J R
JR
Sánez-Madrazo
N
N
D018322:Angiofibroma / Q000175:diagnosis* / Q000601:surgery; D005142:Eyelid Neoplasms / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D013508:Ophthalmologic Surgical Procedures / Q000379:methods; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000601:surgery; D016896:Treatment Outcome; D014402:Tuberous Sclerosis / Q000175:diagnosis* / Q000601:surgery