Approach to geminally alkylated azaphthalans via a consecutive double desilylation-alkylation reaction: application to a synthesis of cerpegin.
A new approach to geminally alkylated azaphthalans and an application of this chemistry to the synthesis of the pyridone alkaloid, cerpegin, is reported.
Sarkar
Tarun K
TK
Department of Chemistry, Indian Institute of Technology, Kharagpur, 721302, India. tksr@chem.iitkgp.ernet.in
Basak
Sankar
S
D000470:Alkaloids / Q000138:chemical synthesis*; D000478:Alkylation; D018360:Crystallography, X-Ray; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011728:Pyridones / Q000138:chemical synthesis*
D000470:Alkaloids; D011728:Pyridones; C503349:cerpegin