[Experimental research on the effects of "chang tong oral liquid" on experimental intestinal adhesion in rats].
OBJECTIVE
To study the efficacy of "chang tong oral liquid" (CTOL) on the degree of intestinal adhesion in rats after surgery.


METHODS
SD rat model of intestinal adhesion was made by surgery. After each group was treated continuously for 7 days, serum TNF-alpha level was determined and the degree of intestinal adhesion was graded.


RESULTS
There was a significant difference between the level of TNF-alpha in model group and those in normal group (P < 0.001). The level of TNF-alpha was remarkably decreased by small, medium and big dose of CTOL, as compared with that of model group (P < 0.001).


CONCLUSIONS
CTOL can significantly decrease the graded scores of intestinal adhesion and serum TNF-alpha level. It suggested that CTOL could cure adhesion of intestine in rats.
Chunxia
Wang
W
First Military Medical University, Guangzhou 510515.
Lianbing
Hou
H
D000818:Animals; D004195:Disease Models, Animal; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D007410:Intestinal Diseases / Q000473:pathology / Q000517:prevention & control*; D008297:Male; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D011183:Postoperative Complications / Q000517:prevention & control; D051381:Rats; D017207:Rats, Sprague-Dawley; D000267:Tissue Adhesions / Q000473:pathology / Q000517:prevention & control*; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D014409:Tumor Necrosis Factor-alpha