Breakthrough in treating gestational diabetes mellitus.
OBJECTIVE
I practise in a remote community in Manitoba. Quite a few of my patients experience gestational diabetes. Their compliance with the insulin regimen is abysmal. Can I give them an oral medication?


CONCLUSIONS
Recent studies have indicated that glyburide does not cross the human placenta and that its effectiveness and safety profiles are similar to those of insulin.
Koren
Gideon
G
D000328:Adult; D016640:Diabetes, Gestational / Q000188:drug therapy*; D005260:Female; D005905:Glyburide / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use; D008350:Manitoba; D010349:Patient Compliance; D011247:Pregnancy; D019035:Rural Health Services
D007004:Hypoglycemic Agents; D007328:Insulin; D005905:Glyburide