Lung cancer among women in France. Analysis of the 904 French women with lung cancer included in the KBP-2000-CPHG study of the French College of General Hospital-based Pneumologists (CPHG).
As the incidence of primary lung cancer in women seems to be increasing in parallel with that of smoking, we conducted an exhaustive epidemiological study in 137 hospitals in 2000. We identified 904 women with proven primary lung cancer (mean age 63.9 years), many of whom have never smoked (32.3%), particularly in cases of adenocarcinoma (43.4%). Small cell cancer accounted for 16.1% of cases. Adenocarcinomas were the most frequent (45.3%) of the non-small cell lung cancer (NSCLC), followed by squamous cell (23.4%), large cell (11.6%) and bronchoalveolar (1.9%) carcinomas. About one third (32.2%) of NSCLC were stage III and 48.1% were stage IV. Over half of all adenocarcinomas were stage IV. According to multivariate analysis, adenocarcinoma is related to less smoking and younger age. In conclusion, many women affected by lung cancer have never smoked. Adenocarcinoma appears to be the most frequent form and more often at a metastatic stage.
Department of Pneumology, Meaux Hospital, 6-8, rue Saint Fiacre, BP 218, 77108 Meaux cedex, France. m-grivaux@ch-meaux.fr
Michel
M
Grivaux
Jean Luc
JL
Breton
Pierre
P
Bombaron
Pierre
P
Kuntz
François Xavier
FX
Lebas
Anas
A
Mehdaoui
Dominique
D
Herman
Philippe
P
David
Jacques
J
Berruchon
Bertrand
B
Delclaux
Mahmoud
M
Zureik
François
F
Blanchon
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000453:epidemiology* / Q000473:pathology; D018288:Carcinoma, Small Cell / Q000453:epidemiology* / Q000473:pathology; D016021:Epidemiologic Studies; D005260:Female; D005602:France / Q000453:epidemiology; D006761:Hospitals / Q000706:statistics & numerical data; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000473:pathology; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012907:Smoking