Microarray analysis of Aeromonas hydrophila cytotoxic enterotoxin-treated murine primary macrophages.
We performed microarray analyses of murine peritoneal macrophages to examine cellular transcriptional responses to a cytotoxic enterotoxin of Aeromonas hydrophila. While 66% of altered genes were common to both primary macrophages and the murine macrophage cell line RAW 264.7, Act caused expression changes of 28 genes specifically in murine peritoneal macrophages.
Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555-1070, USA.
C L
CL
Galindo
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Fadl
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Sha
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Chopra
D016980:Aeromonas hydrophila / Q000378:metabolism*; D000818:Animals; D001426:Bacterial Proteins / Q000494:pharmacology*; D002460:Cell Line; D002478:Cells, Cultured; D004768:Enterotoxins / Q000494:pharmacology*; D005786:Gene Expression Regulation; D017737:Macrophages, Peritoneal / Q000187:drug effects*; D051379:Mice; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D011506:Proteins / Q000235:genetics / Q000378:metabolism*
D001426:Bacterial Proteins; D004768:Enterotoxins; D011506:Proteins; C082174:cytolytic enterotoxin protein, Aeromonas