Drug susceptibility and genetic evaluation of Plasmodium falciparum isolates obtained in four distinct geographical regions of Kenya.
The drug resistance profiles of Plasmodium falciparum isolated from four regions in Kenya were analyzed for drug resistance profiles. We observed variability in resistance to a broad range of antimalarial drugs across Kenya as determined from in vitro drug susceptibility screening and genotyping analysis.
Mbaisi
Abigael
A
U.S. Army Medical Research Unit, Nairobi, Kenya.
Liyala
Pamela
P
Eyase
Fredrick
F
Achilla
Rachel
R
Akala
Hosea
H
Wangui
Julia
J
Mwangi
Josphat
J
Osuna
Finnley
F
Alam
Uzma
U
Smoak
Bonnie L
BL
Davis
Jon M
JM
Kyle
Dennis E
DE
Coldren
Rodney L
RL
Mason
Carl
C
Waters
Norman C
NC
D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D004351:Drug Resistance; D017125:Genes, Protozoan / Q000235:genetics; D005838:Genotype; D006801:Humans; D007630:Kenya / Q000453:epidemiology; D016778:Malaria, Falciparum / Q000453:epidemiology / Q000469:parasitology*; D017720:Molecular Epidemiology; D009154:Mutation / Q000235:genetics; D017891:Pharmacoepidemiology; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000235:genetics*
D000962:Antimalarials