Histopathology of B-cell chronic lymphocytic leukemia.
Histologic and immunohistologic findings of B-cell chronic lymphocytic leukemia/small lymphocytic leukemia are revised in the light of the more recent knowledge on the pathobiology of the disease. The guidelines for the optimal handling of the bioptic samples are provided. The relevance of the examination of trephines and surgical specimens is outlined with special reference to the identification of risk factors in individual patients.
Unit of Haematopathology, Institute of Haematology and Clinical Oncology "L. and A. Seràgnoli", Bologna University, Via Massarenti 9, 40138 Bologna, Italy. pileri@med.unibo.it
Stefano A
SA
Pileri
Elena
E
Sabattini
Claudio
C
Agostinelli
Laura
L
Bodega
Maura
M
Rossi
Pier Luigi
PL
Zinzani
Teresa
T
Marafioti
D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000097:blood / Q000473:pathology*; D008214:Lymphocytes / Q000473:pathology