[Risk factors of thrombotic complications in laparoscopic operations and their prevention].
The possible appearance of thrombotic complications of laparoscopic cholecystectomy (LCE) is one of negative consequences of the effects of carboxyl pneumoperitoneum (CPP). Risk factors of thrombogenesis were investigated in 91 patients who had been subjected to LCE and in 50 patients after open cholecystectomy. It was established that the rate of blood flow in the femoral vein after CPP was 31% lower. The creation of CPP facilitates the development of hypercoagulation. The greatest alteration occurs in the anticoagulation system of blood: "free heparin" becomes 31.7% lower, fibrinolytic activity of blood reduces by 73.1%. Prophylactics of thrombotic complications must be complex and be started with the detection of risk factors and finished with a combination of physical and pharmacological methods.
Sedov
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VM
Salov
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D000368:Aged; D001780:Blood Coagulation Tests; D002763:Cholecystectomy / Q000009:adverse effects; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects*; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007813:Laparotomy; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology* / Q000517:prevention & control; D012307:Risk Factors; D013927:Thrombosis / Q000209:etiology* / Q000517:prevention & control*; D013997:Time Factors
D006495:Heparin, Low-Molecular-Weight