Renal and adrenal tumors in children.
Survival rates for children with kidney tumors approach 90% for even the most advanced stages of disease, but the surgical management of large lesions remains challenging. With the development of additional chemotherapeutic regimens and the use of radiation therapy, survival rates have improved dramatically. The National Wilms' Tumor Study has conducted four long-term studies addressing how adjunctive therapy may be tailored optimally to maximize survival and minimize the exposure to chemotherapy and radiation therapy.
Zderic
Stephen A
SA
Pediatric Urology, University of Pennsylvania School of Medicine, Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Robert Wood Center, 3rd Floor, Philadelphia, PA 19104-4399, USA. zderic@email.chop.edu
D000310:Adrenal Gland Neoplasms / Q000175:diagnosis / Q000628:therapy*; D018268:Adrenocortical Carcinoma / Q000175:diagnosis; D018207:Angiomyolipoma / Q000175:diagnosis; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D030321:Denys-Drash Syndrome / Q000175:diagnosis; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D009367:Neoplasm Staging; D009392:Nephrectomy; D010673:Pheochromocytoma / Q000175:diagnosis / Q000628:therapy; D014057:Tomography, X-Ray Computed; D009396:Wilms Tumor / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000601:surgery