Gonadal and erectile dysfunction in diabetics.
The high prevalence of erectile dysfunction in patients with diabetes is caused mainly by vascular and neurological conditions;nevertheless, hypogonadism may also contribute to erectile dysfunction and to changes in mood, libido, body composition, and bone density. Age, obesity, and the assay used to measure testosterone will affect the diagnosis of hypogonadism. This article focuses on the interaction of these conditions and attempts to explain possible mechanisms for observations reported in the literature.
Department of Medicine, Veterans Affairs Medical Center, Houston, TX 77030, USA.
Rabih A
RA
Hijazi
Marion
M
Betancourt-Albrecht
Glenn R
GR
Cunningham
D017677:Age Distribution; D000368:Aged; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D007172:Erectile Dysfunction / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D005500:Follow-Up Studies; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007006:Hypogonadism / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology*; D015994:Incidence; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D013739:Testosterone / Q000378:metabolism* / Q000627:therapeutic use; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000627:therapeutic use
D007004:Hypoglycemic Agents; D014665:Vasodilator Agents; D013739:Testosterone