Approach to geminally alkylated azaphthalans via a consecutive double desilylation-alkylation reaction: application to a synthesis of cerpegin.
A new approach to geminally alkylated azaphthalans and an application of this chemistry to the synthesis of the pyridone alkaloid, cerpegin, is reported.
Department of Chemistry, Indian Institute of Technology, Kharagpur, 721302, India. tksr@chem.iitkgp.ernet.in
Tarun K
TK
Sarkar
Sankar
S
Basak
D000470:Alkaloids / Q000138:chemical synthesis*; D000478:Alkylation; D018360:Crystallography, X-Ray; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011728:Pyridones / Q000138:chemical synthesis*
D000470:Alkaloids; D011728:Pyridones; C503349:cerpegin