[Cellular immunity state assessed in bronchial and alveolar lavage for experimental animals exposed to the rubber dust].
Experiments on 21 rats helped to study influence of mechanical rubber dust on cellular immunity state in bronchial and alveolar lavage, efficiency of Ruvimine for prophylaxis. Findings are that mechanical rubber dust is strongly cytotoxic. Ruvimine administration during the whole experiment demonstrates therapeutic and prophylactic effect and normalizes local pulmonary phagocytosis.
B K
BK
Zhumabekova
S K
SK
Karabalin
R E
RE
Bakirova
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology / Q000276:immunology*; D004391:Dust; D006034:Glycyrrhetinic Acid / Q000494:pharmacology*; D006035:Glycyrrhiza; D007111:Immunity, Cellular / Q000187:drug effects*; D016676:Macrophages, Alveolar / Q000187:drug effects / Q000276:immunology; D008297:Male; D023421:Models, Animal; D010587:Phagocytosis / Q000187:drug effects; D028321:Plant Preparations / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D012408:Rubber / Q000633:toxicity
D000893:Anti-Inflammatory Agents; D004391:Dust; D028321:Plant Preparations; D012408:Rubber; D006034:Glycyrrhetinic Acid