Supramolecular architecture consisting of an enantiopure amine and an achiral carboxylic acid: application to the enantioseparation of racemic alcohols.
Three-dimensionally dissymmetric cavities are created from an enantiopure amine and an achiral carboxylic acid, which can incorporate the third components to realize the formation of closely packed crystals. The combination demonstrates enantioselective inclusion for 20 kinds of racemic alcohols. The inclusion phenomenon occurs not only during crystallization but also in the solid state.
Kobayashi
Yuka
Y
Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8656, Japan.
Kodama
Koichi
K
Saigo
Kazuhiko
K