AtRGS1 function in Arabidopsis thaliana.
Arabidopsis thaliana RGS1 is a novel "regulator of G-protein signaling" (AtRGS1) protein that consists of an N-terminal seven transmembrane domain characteristic of G-protein-coupled receptors and a C-terminal RGS box. AtRGS1 modulates plant cell proliferation. Atrgs1 mutants are insensitive to glucose and less sensitive to fructose and sucrose, suggesting that sugar signaling in Arabidopsis involves AtRGS1. In addition, sugar metabolism and phosphorylation by hexokinase (HXK) are not required for AtRGS1-mediated sugar signaling, suggesting that AtRGS1 functions in a HXK-independent glucose signaling pathway.
Department of Biology, The University of North Carolina at Chapel Hill, 27599-3280, USA
Jin-Gui
JG
Chen
Alan M
AM
Jones
D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000187:drug effects / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D002455:Cell Division; D005632:Fructose / Q000494:pharmacology; D017343:Genes, Plant; D018525:Germination / Q000187:drug effects; D005947:Glucose / Q000494:pharmacology; D016254:Mutagenesis, Insertional; D030821:Plants, Genetically Modified; D017434:Protein Structure, Tertiary; D020710:RGS Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D012639:Seeds / Q000187:drug effects / Q000254:growth & development; D015398:Signal Transduction; D013395:Sucrose / Q000494:pharmacology
D029681:Arabidopsis Proteins; D020710:RGS Proteins; D005632:Fructose; D013395:Sucrose; D005947:Glucose