Bronchus-associated lymphoid tissue lymphoma arising in a patient with bronchiectasis and chronic Mycobacterium avium infection.
We describe a 67-year-old woman with bronchiectasis and Mycobacterium avium complex infection who underwent wedge resection of her pulmonary infiltrates because they were progressing despite antibiotic therapy. In addition to the expected granulomatous changes, she was found to have a B-cell lymphoma of bronchus associated lymphoid tissue (BALT). Despite normal bone marrow morphology, marrow involvement was demonstrated by flow cytometry. Her lymphoma remains suppressed with antimycobacterial therapy 6 months after resection of bulk disease.
Department of Medicine, Caritas St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02135, USA.
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S
Gaur
E
E
Trayner
L
L
Aish
R
R
Weinstein
D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001984:Bronchial Neoplasms / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D001987:Bronchiectasis / Q000150:complications / Q000188:drug therapy; D002908:Chronic Disease; D002939:Ciprofloxacin / Q000627:therapeutic use; D017291:Clarithromycin / Q000627:therapeutic use; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D009162:Mycobacterium avium; D014376:Tuberculosis / Q000150:complications* / Q000188:drug therapy
D000890:Anti-Infective Agents; D002939:Ciprofloxacin; D017291:Clarithromycin