Delayed-type hypersensitivity to amide local anesthetics.
We present a 54-year-old woman who suffered eczematous eruptions on her face after the administration of lidocaine and mepivacaine for dental surgeries. Patch tests showed delayed-type-hypersensitivity to the amide local anesthetics lidocaine and mepivacaine with cross reaction to other amynoacylderivatives (prilocaine,bupivacaine) but not articaine.
Duque
S
S
Allergy Unit, Hospital Sierrallana, Torrelavega, Spain. mduque@hsll.scsalud.es
Fernández
L
L
D000779:Anesthetics, Local / Q000009:adverse effects*; D002045:Bupivacaine; D002355:Carticaine; D004342:Drug Hypersensitivity / Q000209:etiology*; D004485:Eczema / Q000139:chemically induced; D005148:Facial Dermatoses / Q000139:chemically induced; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced*; D008012:Lidocaine; D008619:Mepivacaine / Q000009:adverse effects* / Q000737:chemistry; D008875:Middle Aged; D011318:Prilocaine
D000779:Anesthetics, Local; D011318:Prilocaine; D008012:Lidocaine; D008619:Mepivacaine; D002355:Carticaine; D002045:Bupivacaine