Use of "tethering" for the identification of a small molecule that binds to a dynamic hot spot on the interleukin-2 surface.
Max Planck Institute of Biochemistry, Department of Molecular Biology, Am Klopferspitz 18, 82152 Martinsried, Germany. berg@biochem.mpg.de
Thorsten
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D001665:Binding Sites; D018360:Crystallography, X-Ray; D007376:Interleukin-2 / Q000737:chemistry / Q000378:metabolism*; D008958:Models, Molecular
D007376:Interleukin-2