[Claritromycin in the modern schemes of eradication of helicobacter infection in patients with ulcer disease].
Out of the fifty patients with duodenal peptic ulcer having received conventional dosages of ranitidin (phamotidin) combined with Denol, metronidazole, and/or tetracycline over two weeks the relapse of the illness within one year occured in 22 percent. Of these, 44 patients had a culture isolated the sensitivity of which to antibiotics was studied with the aid of standard disks or end-point dilutions. 38.7 percent of strains of bacteria were found out to be insensitive to tetracycline, 6.8 percent--to metronidazole, 2.3 percent--to amoxicylline, and no strain was sensitive to claritromycin. The repeated treatment of patients with recurrences of the illness with a combination of omeprazole (20 mg two times daily), amoxicylline (1000 mg twice per day), and claritromycin (500 mg twice per day) for up to 7 days showed no infection in the patients.
Vdovychenko
B I
BI
Danyleĭchenko
V V
VV
Fedechko
I M
IM
Savyts'kyĭ
Ia M
IaM
Shvydkyĭ
Ia B
IaB
Kyrychyns'kyĭ
V H
VH
Vdovychenko
A V
AV
D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D017291:Clarithromycin / Q000008:administration & dosage / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004381:Duodenal Ulcer / Q000188:drug therapy* / Q000382:microbiology / Q000517:prevention & control; D005260:Female; D016481:Helicobacter Infections / Q000188:drug therapy* / Q000382:microbiology / Q000517:prevention & control; D016480:Helicobacter pylori / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D055502:Secondary Prevention; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D017291:Clarithromycin