Oral lichen planus: a clinical and morphometric study of oral lesions in relation to clinical presentation.
Oral lichen planus (OLP) is a chronic inflammatory disease with different clinical presentations that can be classified as reticular or atrophic-erosive. Sixty-two OLP patients were studied to evaluate the clinical-pathologic characteristics of their OLP lesions and to investigate possible differences in their biological behavior. The most common clinical presentation was the reticular type (62.9% vs 37.1%). Atrophic-erosive presentations showed significantly longer evolution (chi square=4.454; p=0.049), more extensive lesions (chi square=16.211; p=0.000) and more sites affected than reticular ones (chi square=10.048; p=0.002). Atrophic-erosive OLP was more frequently found on the tongue, gingiva and floor of the mouth. No statistically significant differences could be identified between reticular and atrophic-erosive clinical presentations in terms of age, sex, tobacco habit, plasma cortisol level and depth of inflammatory infiltrate. We concluded that the classification of OLP lesions as reticular vs atrophic-erosive is a simple, easy to use classification that can identify clinical presentations with different biological behavior.
Seoane
Juan
J
Stomatology Department, School of Medicine and Dentistry, University of Santiago de Compostela, Santiago de Compostela, Spain. jseoanel@usc.es
Romero
María Amparo
MA
Varela-Centelles
Pablo
P
Diz-Dios
Pedro
P
Garcia-Pola
María José
MJ
D000367:Age Factors; D001284:Atrophy; D001706:Biopsy; D003116:Color; D005260:Female; D005882:Gingival Diseases / Q000145:classification / Q000473:pathology; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000652:urine; D007091:Image Processing, Computer-Assisted; D007249:Inflammation; D017676:Lichen Planus, Oral / Q000145:classification* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009060:Mouth Floor / Q000473:pathology; D012737:Sex Factors; D012907:Smoking; D013997:Time Factors; D014060:Tongue Diseases / Q000145:classification / Q000473:pathology; D014741:Video Recording
D006854:Hydrocortisone