Development of tyrosinase labile protecting groups for amines.
[reaction: see text] The development of two novel protecting groups for amines is described. Thus, a range of amines have been converted to ureas, and the deprotection of these upon exposure to mushroom tyrosinase (E.C. 1.14.18.1) has been demonstrated.
Osborn
Helen M I
HM
School of Chemistry, University of Reading, Whiteknights, Reading, RG6 6AD, UK. h.m.i.osborn@rdg.ac.uk
Williams
Nana Aba O
NA
D000363:Agaricales / Q000201:enzymology*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D014442:Monophenol Monooxygenase / Q000378:metabolism*; D014508:Urea / Q000737:chemistry*
D000588:Amines; D014508:Urea; D014442:Monophenol Monooxygenase