Development of real-time thermal neutron monitor using boron-loaded plastic scintillator with optical fiber for boron neutron capture therapy.
A new thermal neutron monitor for boron neutron capture therapy was developed in this study. We called this monitor equipped boron-loaded plastic scintillator that uses optical fiber for signal transmission as an [scintillator with optical fiber] SOF detector. A water phantom experiment was performed to verify how the SOF detector compared with conventional method of measuring thermal neutron fluence. Measurements with a single SOF detector yielded indistinguishable signals for thermal neutrons and gamma rays. To account for the gamma ray contribution in the signal recorded by the SOF detector, a paired SOF detector system was employed. This was composed of an SOF detector with boron-loaded scintillator and an SOF detector with a boron-free scintillator. The difference between the recorded counts of these paired SOF detectors was used as the measure of the gamma ray contribution in the measured neutron fluence. The paired SOF detectors were ascertained to be effective in measuring thermal neutron flux in the range above 10(6)(n/cm(2)/s). Clinical trials using paired SOF to measure thermal neutron flux during therapy confirmed that paired SOF detectors were effective as a real-time thermal neutron flux monitor.
Ishikawa
M
M
Research Center for Nuclear Science and Technology, The University of Tokyo, 2-11-16 Yayoi Bunkyo-ku, Tokyo 113-0032, Japan. masayori@rcnst.u-tokyo.ac.jp
Ono
K
K
Sakurai
Y
Y
Unesaki
H
H
Uritani
A
A
Bengua
G
G
Kobayashi
T
T
Tanaka
K
K
Kosako
T
T
D016754:Boron Neutron Capture Therapy / Q000295:instrumentation*; D001932:Brain Neoplasms / Q000532:radiotherapy; D005336:Fiber Optic Technology; D006801:Humans; D008545:Melanoma / Q000532:radiotherapy; D055100:Optical Fibers; D019047:Phantoms, Imaging; D011874:Radiometry / Q000295:instrumentation / Q000706:statistics & numerical data; D012588:Scintillation Counting / Q000295:instrumentation* / Q000706:statistics & numerical data