Pancreatic metastases: observations of three cases and review of the literature.
BACKGROUND
The aim of the study is to analyze pancreatic metastases and their clinical, radiological, therapeutic and prognostic features.


METHODS
Three cases of pancreatic metastases observed and a world literature review of 333 cases were recorded.


RESULTS
Pancreatic metastases are due more frequently to renal cell carcinoma; they are usually metachronous and characterized by a long period of time between the resection of the primary tumor and their detection. The differential diagnosis with other pancreatic masses is difficult, but an accurate anamnesis, some peculiar findings of imaging techniques and percutaneous fine needle aspiration could allow preoperative diagnosis. Pancreatic resections are the treatment of choice allowing the better palliation and improving survival. 150/234 pancreatic metastases underwent pancreatic resections (resectability index = 64.1%); 88/132 patients are alive with a mean follow-up of 27.1 months; of the 44 dead patients the mean survival time was 21.3 months. Among pancreatic metastases the primary tumor with better prognosis is renal cell carcinoma.


CONCLUSIONS
Pancreatic metastases are rare; their preoperative diagnosis is difficult but useful and possible. Surgical resection is suggested because the patient still may have a prolonged survival.
Department of Surgical and Anaesthesiological Sciences, 1st Surgical Clinic, University of Bologna, Italy.
Francesco
F
Minni
Riccardo
R
Casadei
Barbara
B
Perenze
Vincenzo Maria
VM
Greco
Nicola
N
Marrano
Alessandra
A
Margiotta
Domenico
D
Marrano
D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000556:secondary* / Q000601:surgery; D036542:Tomography, Spiral Computed / Q000379:methods; D017211:Treatment Failure; D016896:Treatment Outcome