Mice susceptible to SARS coronavirus.
Murine models of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) will greatly advance research on this emerging virus. When BALB/c mice were simultaneously inoculated intranasally and orally, replication of SARS-CoV was found in both lung and intestinal tissue.
Wentworth
David E
DE
New York Department of Health, Albany 12201-2002, USA. dwentwor@wadsworth.org
Gillim-Ross
Laura
L
Espina
Noel
N
Bernard
Kristen A
KA
D000818:Animals; D004195:Disease Models, Animal; D006801:Humans; D007422:Intestines / Q000821:virology; D008168:Lung / Q000821:virology; D051379:Mice; D008807:Mice, Inbred BALB C; D045473:Severe acute respiratory syndrome-related coronavirus / Q000472:pathogenicity*; D045169:Severe Acute Respiratory Syndrome / Q000503:physiopathology*; D014779:Virus Replication