Essential fatty acids and their role in the treatment of impulsivity disorders.
Essential fatty acids (EFAs) have been shown to benefit patients with depression, schizophrenia and dementia. More recently, their role in disorders characterised by impulsivity has attracted some attention. The psychiatric conditions of attention-deficit hyperactivity disorder and borderline personality disorder as well as the phenomena of deliberate self-harm and violence have been ameliorated by the supplementation of EFAs in a number of recent clinical trials. This paper summarises the burgeoning clinical and basic research indicating the existence of significant deficits of EFAs in impulsivity disorders and the supplementation studies of EFAs in these diverse conditions, all of which remain a major therapeutic challenge.
Hallahan
Brian
B
The Royal College of Surgeons of Ireland, Beaumont Hospital, Dublin, Ireland.
Garland
Malcolm R
MR
D000374:Aggression / Q000502:physiology; D001289:Attention Deficit Disorder with Hyperactivity / Q000178:diet therapy / Q000453:epidemiology / Q000378:metabolism* / Q000628:therapy*; D003193:Compulsive Personality Disorder / Q000178:diet therapy / Q000453:epidemiology / Q000378:metabolism / Q000628:therapy; D005228:Fatty Acids, Essential / Q000378:metabolism*; D006801:Humans; D010554:Personality Disorders / Q000178:diet therapy / Q000453:epidemiology / Q000378:metabolism* / Q000628:therapy*; D012701:Serotonin / Q000378:metabolism
D005228:Fatty Acids, Essential; D012701:Serotonin