Nausea and vomiting associated with cancer chemotherapy: drug management in theory and in practice.
The function of cytotoxics is to damage cells, and it makes teleological sense for the body to expel them as soon after ingestion as possible. Ideally, from the body's point of view, they should simply be avoided, and it is not surprising that the experience of chemotherapy induced nausea and vomiting (CINV) is powerfully aversive. Nausea and vomiting were once among the most intractable and unpleasant experiences of a child undergoing treatment for cancer.
Antonarakis
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ES
University Hospital of Wales, Heath Park, Cardiff CF14 4XN, UK.
Hain
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RD
D000932:Antiemetics / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002648:Child; D018492:Dopamine Antagonists / Q000627:therapeutic use; D006801:Humans; D009325:Nausea / Q000139:chemically induced* / Q000517:prevention & control; D009369:Neoplasms / Q000188:drug therapy*; D012702:Serotonin Antagonists / Q000627:therapeutic use; D014839:Vomiting / Q000139:chemically induced* / Q000517:prevention & control; D014840:Vomiting, Anticipatory / Q000209:etiology
D000932:Antiemetics; D000970:Antineoplastic Agents; D018492:Dopamine Antagonists; D012702:Serotonin Antagonists