Short Communication: Yersinia pseudotuberculosis septicemia in an HIV-infected patient failed HAART.
The first case of septicemia due to Yersinia pseudotuberculosis in an HIV-infected person was reported. The 42-year-old woman was severely immunosuppressed despite a prolonged exposure to HAART. Specific amplicons for inv, yadA, and lcrF genes showed the pathogenetic potential of the Y. pseudotuberculosis serotype O1 isolate. A favorable clinical response to ceftriaxone and levofloxacin was observed.
Dipartimento Clinico, INMI Lazzaro Spallanzani IRCCS, Rome, Italy. antinori@inmi.it
Andrea
A
Antinori
Maria Grazia
MG
Paglia
Patrizia
P
Marconi
Anna
A
Festa
Lucia
L
Alba
Evangelo
E
Boumis
Leopoldo Paolo
LP
Pucillo
Paolo
P
Visca
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D002443:Ceftriaxone / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006801:Humans; D064704:Levofloxacin; D015242:Ofloxacin / Q000627:therapeutic use; D018805:Sepsis / Q000150:complications*; D017211:Treatment Failure; D015011:Yersinia pseudotuberculosis / Q000235:genetics / Q000302:isolation & purification*; D015012:Yersinia pseudotuberculosis Infections / Q000150:complications* / Q000188:drug therapy
D064704:Levofloxacin; D002443:Ceftriaxone; D015242:Ofloxacin