Leiomyosarcoma of the spermatic cord: a light and ultrastructural description of one case.
A case of leiomyosarcoma arising in the spermatic cord is described. A 83-year-old man required medical care for an irreducible inguinal hernia. The patient underwent herniorraphy and transinguinal radical orchiectomy. Macroscopically, the spermatic cord was enlarged by a gray-tan and ill-defined neoplasm measuring 4 x 4 x 3 cm. Histologically, this proliferation was composed of atypical spindle cells with blunted end nuclei and eosinophilic cytoplasm. Immunohistochemistry and ultrastructure confirmed the smooth muscle nature of the neoplastic cells. The diagnosis of leiomyosarcoma of the spermatic cord was made. To improve the assignment of this rare lesion to its specific anatomic location, we analyzed the immunohistochemical and ultrastructural characteristics of the smooth muscle tumoral cells and in particular those of the intracellular filament aggregates.
Alberghini
Marco
M
Department of Surgical Pathology, IOR, Bologna, Italy. marco.alberghini@ior.it
Zanella
Licciana
L
Bacchini
Patrizia
P
Maltarello
Maria Cristina
MC
Maraldi
Nadir Mario
NM
Bertoni
Franco
F
D000199:Actins / Q000378:metabolism; D000368:Aged; D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000378:metabolism; D005834:Genital Neoplasms, Male / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007890:Leiomyosarcoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D008297:Male; D009130:Muscle, Smooth / Q000378:metabolism / Q000648:ultrastructure; D009364:Neoplasm Recurrence, Local; D013085:Spermatic Cord / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome
D000199:Actins; D014408:Biomarkers, Tumor