Tinea imbricata: autosomal dominant pattern of susceptibility in a polygamous indigenous family of the Nahuatl zone in Mexico.
We report on 9 confirmed cases of tinea imbricata (Tokelau, infection due to Trichophyton concentricum) out of 16 family members. They had a common mother with three different fathers. The genetic analysis of the family suggests an autosomal dominant pattern of susceptibility. Most cases (8/9) were presented as concentric and lamellar forms. One patient also had onychomycosis due to T. concentricum. Only two out of nine cases had a positive response to trichophytin.
Bonifaz
A
A
Department of Dermatology and Mycology, Hospital General de México, Mexico City. bonyalx@servidor.unam.mx
Araiza
J
J
Koffman-Alfaro
Susana
S
Paredes-Solis
Vanessa
V
Cuevas-Covarrubias
S
S
Rivera
M R
MR
D000293:Adolescent; D000328:Adult; D002648:Child; D005190:Family; D005260:Female; D005799:Genes, Dominant; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D008393:Marriage; D008800:Mexico; D008875:Middle Aged; D010375:Pedigree; D044382:Population Groups; D014005:Tinea / Q000235:genetics* / Q000382:microbiology; D014249:Trichophyton