Immune responses and parasite transmission in blood-feeding insects.
The detailed model of insect immunity being built for Drosophila, allied to mass sequencing programs for blood-feeding insects, has led to advances in our understanding of the interaction between pathogens and insect vectors. An outline of insect immunity is given here based on the Drosophila studies, which is used as a framework to discuss recent work on Plasmodium-mosquito and Trypanosoma-tsetse interactions.
Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK. m.lehane@liverpool.ac.uk
Michael J
MJ
Lehane
Serap
S
Aksoy
Elena
E
Levashina
D000818:Animals; D000852:Anopheles / Q000276:immunology* / Q000469:parasitology; D004331:Drosophila melanogaster / Q000276:immunology*; D007303:Insect Vectors / Q000276:immunology* / Q000469:parasitology; D008288:Malaria / Q000276:immunology / Q000469:parasitology / Q000635:transmission; D010961:Plasmodium / Q000276:immunology*; D014345:Trypanosoma / Q000276:immunology*; D014352:Trypanosomiasis / Q000276:immunology / Q000469:parasitology / Q000635:transmission; D014370:Tsetse Flies / Q000276:immunology* / Q000469:parasitology