Prenatal origin of GATA1 mutations may be an initiating step in the development of megakaryocytic leukemia in Down syndrome.
Jeffrey W
JW
Taub
Gina
G
Mundschau
Yubin
Y
Ge
Janet M
JM
Poulik
Faisal
F
Qureshi
Tanya
T
Jensen
S Jill
SJ
James
Larry H
LH
Matherly
Joshua
J
Wechsler
John D
JD
Crispino
D004268:DNA-Binding Proteins / Q000235:genetics*; D004314:Down Syndrome / Q000150:complications* / Q000235:genetics*; D050981:Erythroid-Specific DNA-Binding Factors; D050982:GATA1 Transcription Factor; D006801:Humans; D007947:Leukemia, Megakaryoblastic, Acute / Q000150:complications* / Q000235:genetics*; D009154:Mutation; D014157:Transcription Factors / Q000235:genetics*
D004268:DNA-Binding Proteins; D050981:Erythroid-Specific DNA-Binding Factors; D050982:GATA1 Transcription Factor; C494688:GATA1 protein, human; D014157:Transcription Factors