Successful surrogate pregnancy after ovarian transposition, pelvic irradiation and hysterectomy.
BACKGROUND
Treatment of cervical cancer is often effective but at the cost of the woman's fertility. Ovarian transposition with subsequent oocyte retrieval and surrogate pregnancy can enable these patients to become genetic parents. We present the third reported such case.


METHODS
A 22-year-old woman was diagnosed with bulky, stage IB cervical cancer. Following transposition of both ovaries to the upper abdomen, she underwent pelvic irradiation followed by total abdominal hysterectomy. Eleven years later she presented for assisted reproduction. Two oocytes were retrieved following ovarian stimulation and transcutaneous, abdominal oocyte retrieval. One embryo was transferred to the gestational surrogate, resulting in a single intrauterine pregnancy and successful delivery at term.


CONCLUSIONS
These procedures can preservefertility while successfully treating cervical cancer.
Zinger
Michael
M
Department of Obstetrics and Gynecology, Edward Hospital, Naperville, Illinois, USA. mzinger@usa.net
Liu
James H
JH
Husseinzadeh
Nader
N
Thomas
Michael A
MA
D004624:Embryo Transfer; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects / Q000379:methods; D007246:Infertility / Q000209:etiology / Q000628:therapy*; D010053:Ovary / Q000601:surgery; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D013533:Gestational Carriers; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*