Solvents and malignancy.
Despite the number of substances that fall under the rubric of solvent, only a few are considered to be potential carcinogens. The purpose of this article is to provide readers with an overview of the cancer data that exist for a number of solvents currently in commercial use. These solvents include chloroform, carbon tetrachloride, methylene chloride (dichloromethane) trichloroethylene, tetrachloroethylene (perchloroethylene), and 1,4-dioxane. Although benzene also would be considered a solvent, the data concerning its carcinogenic potential are presented in another article in this issue and are not discussed in this article.
Wernke
Michael J
MJ
BBL Sciences, 2940 Kerry Forest Parkway, Suite 102, Tallahassee, FL 32309-6824, USA. mw1@bbl-inc.com
Schell
John D
JD
D000818:Animals; D002251:Carbon Tetrachloride / Q000009:adverse effects; D002725:Chloroform / Q000009:adverse effects; D004146:Dioxanes / Q000009:adverse effects; D004781:Environmental Exposure / Q000009:adverse effects*; D006801:Humans; D008752:Methylene Chloride / Q000009:adverse effects; D009369:Neoplasms / Q000139:chemically induced* / Q000453:epidemiology; D012997:Solvents / Q000009:adverse effects*; D014241:Trichloroethylene / Q000009:adverse effects
D004146:Dioxanes; D012997:Solvents; D014241:Trichloroethylene; D008752:Methylene Chloride; D002725:Chloroform; D002251:Carbon Tetrachloride; C025223:1,4-dioxane