Transfusion-related acute lung injury (TRALI).
Transfusion is an inevitable event in the life of many individuals. Transfusion medicine personnel attempt to provide blood products that will result in a safe and harmless transfusion. However, this is not always possible since no laboratory test gives totally accurate and reliable results all the time and testing in routine transfusion services is devoted primarily to the identification of red blood cell problems. Thus, when patients are transfused, several possible adverse effects may occur in the transfused patient even though quality testing indicates no potential problem. These adverse events include infectious complications, hemolytic reactions, anaphylaxis, urticaria, circulatory overload, transfusion-associated graft-versus-host disease, chills and fever, immunomodulation, and transfusion-related acute lung injury (TRALI).
Roberts
George H
GH
Department of Clinical Laboratory Science and Radiologic Technology, The University of Louisiana at Monroe, 700 University Avenue, Monroe, LA 71209-0440, USA. groberts@ulm.edu
D001787:Blood Group Incompatibility; D001804:Blood Transfusion, Autologous; D003937:Diagnosis, Differential; D017707:Erythrocyte Transfusion / Q000009:adverse effects*; D006680:HLA Antigens; D006801:Humans; D008171:Lung Diseases / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011654:Pulmonary Edema / Q000209:etiology*; D012128:Respiratory Distress Syndrome / Q000209:etiology* / Q000628:therapy
D006680:HLA Antigens