Quantitative MR imaging of the neocortex.
This article provides an overview of novel MR image analysis methods applied to the quantitative assessment of the neocortex in various forms of epilepsy. Postacquisition processing methods, such as voxel-based morphometry and texture analysis, involve the use of computer software to manipulate, enhance, and classify image information in a digital format. These techniques have the potential to demonstrate subtle abnormalities that are not identified by eye because of anatomic variability. Information provided by quantitative MR imaging of the neocortex may be important for the identification of accurate predictors of surgical outcome and may refine the selection of surgical candidates, particularly those with "nonlesional" neocortical epilepsy.
Bernasconi
Andrea
A
Department of Neurology and McConnell Brain Imaging Center, Montreal Neurological Institute and Hospital, McGill University, Montreal H3A 2B4, Quebec, Canada. andrea@bic.mni.mcgill.ca
D004828:Epilepsies, Partial / Q000209:etiology / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging; D019579:Neocortex / Q000002:abnormalities / Q000473:pathology*