Expression of E26 transformation specific (ETS-1) related to angiogenesis in ovarian endometriosis.
ETS-1 in ovarian endometriomas was significantly positively correlated with microvessel counts (MVCs), but ETS-1 and MVC were not significantly altered during the menstrual cycle. Because ETS-1 persistently expresses in the subepithelial area of endometriotic endometrium, this might contribute to the growth of ovarian endometriomas via subepithelial angiogenesis independently of the menstrual cycle.
Sakaguchi
Hideki
H
Fujimoto
Jiro
J
Aoki
Ikumi
I
Toyoki
Hiroshi
H
Sato
Eriko
E
Tamaya
Teruhiko
T
D000328:Adult; D004715:Endometriosis / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D005169:Factor VIII / Q000032:analysis; D005260:Female; D005786:Gene Expression Regulation / Q000235:genetics*; D006801:Humans; D007150:Immunohistochemistry; D008833:Microcirculation / Q000473:pathology; D009389:Neovascularization, Pathologic / Q000235:genetics*; D010049:Ovarian Diseases / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D050784:Proto-Oncogene Protein c-ets-1; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D050783:Proto-Oncogene Proteins c-ets; D012016:Reference Values; D014157:Transcription Factors / Q000235:genetics*
C494041:ETS1 protein, human; D050784:Proto-Oncogene Protein c-ets-1; D011518:Proto-Oncogene Proteins; D050783:Proto-Oncogene Proteins c-ets; D014157:Transcription Factors; D005169:Factor VIII