Meningioangiomatosis in young dogs: a case series and literature review.
Meningioangiomatosis (MA) is a proliferative disorder of the central nervous system (CNS) that has been reported rarely in humans and sporadically in dogs. Meningioangiomatosis may occur in the brainstem or cervical spinal cord of young dogs and can be identified tentatively by magnetic resonance imaging. The histopathologic hallmark of MA is a leptomeningeal plaque that extends along the CNS microvasculature and invades the adjacent neural parenchyma. This case series describes the neurologic signs, clinical progression, diagnostic imaging, and neuropathology of 4 dogs with MA. The 4 dogs with MA are compared and contrasted with 4 previously reported cases in dogs as well as with their human counterpart.
Department of Clinical Studies, The Mathew J. Ryan Veterinary Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Todd M
TM
Bishop
James
J
Morrison
Brian A
BA
Summers
Alexander
A
deLahunta
Scott J
SJ
Schatzberg
D000798:Angiomatosis / Q000175:diagnosis / Q000662:veterinary*; D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D005260:Female; D008279:Magnetic Resonance Imaging; D008297:Male; D013118:Spinal Cord Diseases / Q000175:diagnosis / Q000662:veterinary*