Acid-catalyzed rearrangement of diaryl hydrazides for the efficient synthesis of functionalized 2,2'-diamino-1,1'-biaryls.
Diaryl hydrazides prepared from the Pd(0)- or Cu(I)-catalyzed coupling reactions of aryl hydrazides and aryl halides underwent the acid-catalyzed rearrangements to a series of previously unknown 2,2'-diaminobiaryls in good overall yields. The mildness of the reaction conditions allows the presence of various functional groups.
Department of Chemistry, Hanyang University, Seoul 131-791, Korea.
Young-Kwan
YK
Lim
Jin-Woo
JW
Jung
Haiwon
H
Lee
Cheon-Gyu
CG
Cho