[Immunotoxicity of aluminum chloride].
Aluminum chloride was tested for its effect on primary T-dependent humoral immune response. The administration of aluminum chloride in the genotoxic dose (0.04 M) caused in mice a profound immunosuppressive effect accompanied by diminished thymic and splenic cellularity. The findings suggest that aluminum chloride possesses marked immunotoxic properties.
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D000077410:Aluminum Chloride; D017607:Aluminum Compounds / Q000633:toxicity*; D000818:Animals; D002712:Chlorides / Q000633:toxicity*; D007108:Immune Tolerance; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009152:Mutagenicity Tests; D013154:Spleen / Q000166:cytology / Q000187:drug effects*; D013601:T-Lymphocytes / Q000187:drug effects*; D013950:Thymus Gland / Q000166:cytology / Q000187:drug effects
D017607:Aluminum Compounds; D002712:Chlorides; D000077410:Aluminum Chloride