Magnesium and branched chain amino acids in rats intoxicated with Pb2+ or Cd2+ and receiving certain bioflavonoids or bioflavonoids with glutamine.
Experiment was carried on Wistar male rats. Eleven groups, each of 6 rats, were given: group I: plumbum nitrate (500 mg Pb/dm3), group II: plumbum ions--500 mg Pb/dm3 and quercetin--200 mg/dm3, group III the same what group II and glutamine 4 g/dm3, group IV: Pb(NO3)2--500 mg Pb/dm3 and catechin (200 mg/dm3), and group V the same as group IV, Pb ions, catechin, and additionally glutamine--4 g/dm3. The IA - VA groups obtained the same that groups I-V but they received instead of lead cadmium chloride in amount of 500 mg Cd/dm3. Group IX was a control group, and that animals received redistilled water to drink. After six weeks of experiment blood, liver and kidneys were collected, and magnesium and branched amino acids concentrations were determined. The aim of these studies was to determine the influence of administered quercetin and catechin individually or with free glutamine on magnesium and BCAAs concentrations in blood serum, liver and kidneys of rats.
General Chemistry, Department of Medical University in Lublin, Poland.
Kazimierz
K
Pasternak
Maria
M
Szpetnar
Anna
A
Boguszewska
D000597:Amino Acids, Branched-Chain / Q000378:metabolism*; D000818:Animals; D002104:Cadmium / Q000378:metabolism*; D002392:Catechin / Q000378:metabolism; D005419:Flavonoids / Q000378:metabolism*; D005973:Glutamine / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism; D007854:Lead / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008274:Magnesium / Q000097:blood*; D008297:Male; D011794:Quercetin / Q000378:metabolism; D051381:Rats
D000597:Amino Acids, Branched-Chain; D005419:Flavonoids; D002104:Cadmium; D005973:Glutamine; D007854:Lead; D002392:Catechin; D011794:Quercetin; D008274:Magnesium