Group A streptococcal puerperal sepsis with retroperitoneal involvement developing in a late postpartum woman: case report.
Group A beta-hemolytic streptococci cause a wide range of infectious diseases such as pharyngitis, impetigo, rheumatic fever, and even septic shock. Group A streptococcal puerperal sepsis is uncommon today, but recent reports indicate a reemergence of virulent strains can cause toxic-mediated shock and multiple organ failure. We present a case report of a 29-year-old postpartum woman after cesarean section who presented group A streptococcal puerperal sepsis. Furthermore, we discuss the GAS strain in this patient and its relation with close contact among family members. The group A streptococci (GAS) were isolated from the patient's retroperitoneal fluid and from her husband's throat swab, respectively. Both isolates were shown to be identical: M type 1. It is well known that exotoxin A produced by M1 or M3 serotypes of the organisms plays a crucial role in streptococcal toxic shock syndrome (STSS). We conclude that in this patient, close contacts of persons with GAS appear to be at risk for colonization with identical strains of STSS-causing GAS such as M1 or M3 serotypes. Therefore, the appropriate antibiotic including antibiotic prophylaxis for close contact should be considered.
Department of Surgery, United States Naval Hospital Yokosuka, Japan.
Keiko
K
Okumura
Richard
R
Schroff
Rwanda
R
Campbell
Lucas
L
Nishioka
Eric
E
Elster
D000328:Adult; D002585:Cesarean Section; D005260:Female; D006801:Humans; D049590:Postpartum Period; D011247:Pregnancy; D011645:Puerperal Infection / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D012187:Retroperitoneal Space / Q000382:microbiology*; D018805:Sepsis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D013290:Streptococcal Infections / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D013297:Streptococcus pyogenes / Q000302:isolation & purification*