Guideline for the production of multicentre physiological reference values using the same measurement system. A proposal of the Catalan Association for Clinical Laboratory Sciences.
This article is intended as a guide for the production of biological reference values of healthy people (physiological reference values) by several clinical laboratories using the same measurement system. This guide is a proposal from the Catalan Association of Clinical Laboratory Sciences to be applied worldwide at a regional level. This guide makes it possible for all clinical laboratories in a region using the same measurement system to adopt the same physiological reference limits. The model presented here is based on the assumption that the production of physiological reference values is a professional task that should be shared by both clinical laboratories and the in vitro diagnostics industry.
Servei de Bioquímica Clínica, Hospital Universitari de Bellvitge, I'Hospitalet de Llobregat, Catalonia, Spain. xfa@csub.scs.es
Xavier
X
Fuentes-Arderiu
Roser
R
Mas-Serra
Alba
A
Alumà-Trullàs
Maria Isabel
MI
Martí-Marcet
Dolors
D
Dot-Bach
D019963:Clinical Chemistry Tests / Q000592:standards*; D019411:Clinical Laboratory Techniques / Q000592:standards*; D006801:Humans; D015337:Multicenter Studies as Topic / Q000592:standards; D012015:Reference Standards; D012016:Reference Values; D012107:Research Design