[The clinical observation of treating acne vulgaris with "xiao cuo fang"].
OBJECTIVE
To observe the clinical curative effect of Chinese medicine "xiao cuo fang" combined with adapalene gel in the treatment of acne vulgaris.


METHODS
133 patients with acne vulgaris were divided into treatment group (80 cases) and control group (53 cases) randomly. The treatment group topically applied "xiao cuo fang" combined with 0.1% adapalene gel, the control group topically applied 0.03% retinoic acid cream. After 8 weeks, we observed the reductive percentage of skin injury, the effective rate of the treatment and the incidence rate of adverse reactions.


RESULTS
The average of overall skin injury, the average of inflammatory and of non-inflammatory in the treatment group reduced 82.7%, 81.0%, 84.3%, respectively, and the control group reduced 60.5%, 59.1%, 61.9%. The difference between them had obvious significance (P < 0.05). The effect rate of the treatment group was 85.0%, and the control group was 69.8%. The difference between them had obvious significance (P < 0.05). The incidence rate of adverse reaction of the treatment group was 27.5%, and the control group was 45.3%. The difference between them had obvious significance (P <0.05).


CONCLUSIONS
The curative effect of "xiao cuo fang" combined with adapalene gel in the treatment of acne vulgaris is precise, and the side effects are small.
Jiangmen Dermatology Hospital, Jiangmen 529030.
Chen
C
Biyun
D000152:Acne Vulgaris / Q000097:blood / Q000188:drug therapy*; D000068816:Adapalene; D000287:Administration, Topical; D000328:Adult; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D005782:Gels; D006801:Humans; D008297:Male; D009281:Naphthalenes / Q000008:administration & dosage*; D008517:Phytotherapy; D014212:Tretinoin / Q000008:administration & dosage*
D004365:Drugs, Chinese Herbal; D005782:Gels; D009281:Naphthalenes; D000068816:Adapalene; D014212:Tretinoin