Three-dimensional magnetic resonance imaging technique for myocardial-delayed hyperenhancement: a comparison with the two-dimensional technique.
OBJECTIVE
To compare two-dimensional and three-dimensional techniques in the detection of myocardial infarction (MI) and in the grading transmural extent (TE).


METHODS
Twelve patients with clinically proven MI were examined using two-dimensional and three-dimensional techniques with cardiac-gated, breath-hold, T1-weighted gradient echo sequence with an inversion recovery pulse following gadopentetate dimeglumine (Gd-DTPA) at 0.2 mmol/kg. Contrast-to-noise, signal-to-noise, and signal intensity ratios (CNR, SNR, and SIR, respectively) were derived and compared for each technique.


RESULTS
From two-dimensional to three-dimensional, statistical significant difference was found in the mean CNR (11.65 vs. 56.59; P = 0.002), SNR (18.03 vs. 76.90; P < 0.001), and SIR (3.6 vs. 6.36; P = 0.05). Intraobserver agreement (kappa) between two-dimensional and three-dimensional were R1 = 74% and R2 = 90%. Interobserver agreements between the readers were two-dimensional = 77% and three-dimensional = 79%.


CONCLUSIONS
Mean CNR, SNR, and SIR are significantly increased in the three-dimensional technique compared to the conventional two-dimensional technique.
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. statli@partners.org
Servet
S
Tatli
Kelly H
KH
Zou
Mark
M
Fruitman
H Glenn
HG
Reynolds
Thomas
T
Foo
Raymond
R
Kwong
E Kent
EK
Yucel
D000328:Adult; D000368:Aged; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000503:physiopathology; D015588:Observer Variation
D003287:Contrast Media; D019786:Gadolinium DTPA