Human metapneumovirus and severity of respiratory syncytial virus disease.
We screened 23 children with severe respiratory syncytial virus (RSV) disease and 23 children with mild RSV disease for human metapneumovirus (HMPV). Although HMPV was circulating in Connecticut, none of the 46 RSV-infected patients tested positive for HMPV. In our study population, HMPV did not contribute to the severity of RSV disease.
Lazar
Isaac
I
Yale University School of Medicine, New Haven, Connecticut 06520-8064, USA.
Weibel
Carla
C
Dziura
James
J
Ferguson
David
D
Landry
Marie L
ML
Kahn
Jeffrey S
JS
D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases; D029121:Metapneumovirus / Q000302:isolation & purification / Q000472:pathogenicity*; D018184:Paramyxoviridae Infections / Q000150:complications*; D018357:Respiratory Syncytial Virus Infections / Q000150:complications / Q000503:physiopathology*; D018113:Respiratory Syncytial Virus, Human / Q000472:pathogenicity*; D012720:Severity of Illness Index