Epidemic resurgence of Chikungunya virus in democratic Republic of the Congo: identification of a new central African strain.
The resurgence of Chikungunya virus is described during an urban epidemic in Kinshasa Democratic Republic of the Congo, after 39 years without any isolation of the virus. Chikungunya virus was isolated in sera from nine patients with clinical symptoms. A 1,200 bp long partial sequence of the E1/3'UTR genomic region was determined for each isolate. All sequences clustered in the central African lineage. They constitute Chikungunya virus reference sequences for the Democratic Republic of the Congo.
Pastorino
B
B
Unité de Virologie, Laboratoire Associé au Centre National de Référence Pour les Arboviroses, Institut de Médecine Tropicale du Service de Santé des Armées, Marseille Armées, France.
Muyembe-Tamfum
J J
JJ
Bessaud
M
M
Tock
F
F
Tolou
H
H
Durand
J P
JP
Peyrefitte
C N
CN
D018354:Alphavirus Infections / Q000453:epidemiology* / Q000821:virology; D000914:Antibodies, Viral / Q000097:blood; D002646:Chikungunya virus / Q000145:classification / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification; D021821:Communicable Diseases, Emerging / Q000453:epidemiology* / Q000821:virology; D015023:Democratic Republic of the Congo / Q000453:epidemiology; D004196:Disease Outbreaks; D006801:Humans; D016778:Malaria, Falciparum / Q000150:complications; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D017422:Sequence Analysis, DNA
D000914:Antibodies, Viral