The end in sight.
The HP1 heterochromatic protein has become an archetypical example of a chromatin protein recruited by binding a specific histone modification. Surprisingly, recent work in Drosophila reveals that the essential function of HP1 is accomplished by another mode of binding.
Department of BCMP, Harvard Medical School, 240 Longwood Ave, C1-204, Boston, MA 02115, USA.
Kami
K
Ahmad
D000818:Animals; D002843:Chromatin / Q000378:metabolism; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism*; D004260:DNA Repair; D029721:Drosophila Proteins / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000235:genetics; D011485:Protein Binding; D016615:Telomere / Q000378:metabolism*
D002843:Chromatin; D002868:Chromosomal Proteins, Non-Histone; D029721:Drosophila Proteins; C452193:heterochromatin protein 1, Drosophila