Colonization with extraintestinal pathogenic Escherichia coli among nursing home residents and its relationship to fluoroquinolone resistance.
In a cross-sectional fecal prevalence survey involving 49 residents of a Veterans Affairs nursing home, 59% of subjects were colonized with extraintestinal pathogenic Escherichia coli (ExPEC), 22% were colonized with adhesin-positive E. coli, and 51% were colonized with fluoroquinolone-resistant E. coli. Among 80 unique isolates, adhesins correlated negatively and aerobactin correlated positively with fluoroquinolone resistance.
Maslow
Joel N
JN
Section of Infectious Diseases, Veterans Affairs Medical Center, University and Woodland Ave., Philadelphia, PA 19104, USA. joel.maslow@med.va.gov
Lautenbach
Ebbing
E
Glaze
Thomas
T
Bilker
Warren
W
Johnson
James R
JR
D018829:Adhesins, Bacterial / Q000378:metabolism; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism; D004927:Escherichia coli Infections / Q000382:microbiology*; D005243:Feces / Q000382:microbiology; D024841:Fluoroquinolones / Q000494:pharmacology; D006801:Humans; D006877:Hydroxamic Acids / Q000378:metabolism; D009735:Nursing Homes; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014481:United States; D014493:United States Department of Veterans Affairs; D037521:Virulence Factors
D018829:Adhesins, Bacterial; D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D006877:Hydroxamic Acids; D037521:Virulence Factors; C031819:aerobactin