Tissue Doppler imaging for predicting outcome in patients with cardiovascular disease.
OBJECTIVE
Tissue Doppler imaging is being increasingly used for assessing global ventricular function in systole and diastole, and for quantifying regional wall motion abnormalities both in systolic heart failure with mechanical dyssynchrony and ischemic heart disease. Its use as a predictive tool is recent and the authors review publications relating to this aspect.


RESULTS
Peak early diastolic mitral annular velocity is a powerful predictor of outcome in a variety of cardiovascular conditions and adds incremental value to clinical parameters and standard mitral Doppler inflow velocities. Tissue Doppler imaging can also predict the development of hypertrophic cardiomyopathy in asymptomatic individuals carrying the genetic mutation even before the onset of overt left ventricular hypertrophy. In addition, the standard deviation of the time to peak systolic velocity is a good marker of mechanical asynchrony and can predict reverse remodeling. It may also be useful in identifying individuals with ischemic heart disease and regional wall motion abnormalities who have an adverse outcome.


CONCLUSIONS
Tissue Doppler imaging is a powerful new echocardiographic tool that is now becoming the standard for assessing ventricular function in a variety of situations and diseases.
Division of Cardiology, Department of Medicine & Therapeutics, The Chinese University of Hong Kong, SAR. jesanderson@cuhk.edu.hk
John E
JE
Sanderson
Mei
M
Wang
C M
CM
Yu
D002304:Cardiac Pacing, Artificial; D002318:Cardiovascular Diseases / Q000000981:diagnostic imaging*; D003971:Diastole; D015150:Echocardiography, Doppler / Q000379:methods*; D006801:Humans; D017063:Outcome Assessment, Health Care / Q000379:methods*; D011379:Prognosis; D013599:Systole