[Level of lipid peroxides and activity of antioxidant system enzymes in pulmonary tissue of rats with acute pneumonia].
The model process of acute pneumonia in rats, after 2 hours after intranasal infectioning by Staphylococcus aureus culture, is accompanied with DK and MDA level growth, and SOD and catalase activity increase in pulmonary tissue of males and females. Later, after 6 hours after contamination the growth of POL products content was observed, the SOD and catalase activity in lungs is lowered. At the same time, in females the PLO indexes and SOD activity continue to grow. This suggests that females have more AOS enzymatic reserves than males.
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D000208:Acute Disease; D000818:Animals; D002374:Catalase / Q000378:metabolism; D004195:Disease Models, Animal; D005260:Female; D008054:Lipid Peroxides / Q000378:metabolism*; D008168:Lung / Q000201:enzymology* / Q000378:metabolism*; D008297:Male; D011023:Pneumonia, Staphylococcal / Q000201:enzymology* / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D012737:Sex Factors; D013482:Superoxide Dismutase / Q000378:metabolism
D008054:Lipid Peroxides; D002374:Catalase; D013482:Superoxide Dismutase