Fulminant myocarditis successfully treated with high-dose immunoglobulin.
Fulminant myocarditis is characterized by the rapid development of life-threatening congestive heart failure. Intravenous immunoglobulin (IVIG), by modulating the immune response, may be used for the treatment of acute myocarditis. We report two children with fulminant myocarditis successfully treated with a 10-h infusion of high-dose IVIG. In those cases, a dramatic clinical improvement was achieved, with both cardiac enzymes and myocardial function normalized within 1-2 weeks after treatment.
Kim
Hae Soon
HS
Sohn
Sejung
S
Park
Ji Yun
JY
Seo
Jeong Wan
JW
D000208:Acute Disease; D002648:Child; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D009205:Myocarditis / Q000188:drug therapy*
D016756:Immunoglobulins, Intravenous