Optimization of an accelerator-based epithermal neutron source for neutron capture therapy.
A modeling investigation was performed to choose moderator material and size for creating optimal epithermal neutron beams for BNCT based on a proton accelerator and the (7)Li(p,n)(7)Be reaction as a neutrons source. An optimal configuration is suggested for the beam shaping assembly made from polytetrafluoroethylene and magnesium fluorine to be placed on high current IPPE proton accelerator KG-2.5. Results of calculation were experimentally tested and are in good agreement with measurements.
State Scientific Center of Russian Federation, Institute for Physics and Power Engineering, Bondarenko sq. 1, 249033 Obninsk, Kaluga, Russia. kononov@ippe.ru
O E
OE
Kononov
V N
VN
Kononov
M V
MV
Bokhovko
V V
VV
Korobeynikov
A N
AN
Soloviev
A S
AS
Sysoev
I A
IA
Gulidov
W T
WT
Chu
D W
DW
Nigg
D016754:Boron Neutron Capture Therapy / Q000295:instrumentation* / Q000706:statistics & numerical data; D003198:Computer Simulation; D005160:Facility Design and Construction; D005214:Fast Neutrons / Q000627:therapeutic use*; D006801:Humans; D009010:Monte Carlo Method; D009369:Neoplasms / Q000532:radiotherapy; D010315:Particle Accelerators; D019047:Phantoms, Imaging; D011879:Radiotherapy Dosage