A detailed analysis of rats' spatial memory in a probe trial of a Morris task.
In the present study, we evaluated the search behavior of rats during a probe trial of a Morris water escape task. More specifically, the spatial memory during different stages of a 2 min probe trial in different zones was examined. After rats were trained for 4 days with four trials per day, their spatial memory was tested in a first probe trial. The rats showed a preference for the target quadrant during each of four 30-s intervals. The time in the annulus decreased across the four 30-s intervals. The preference for the previous target quadrant was also observed in a second probe trial, when the rats had received additional training for 4 days with four trials per day. However, the time spent in the annulus was highest during the first 30-s of the probe trial, and was lower and similar during the next three 30-s intervals. Therefore, probe trials of 60s seem to underestimate the spatial ability of rats. It appears that using a quadrant for assessing the performance may overestimate the spatial ability of a rat. Our findings suggest that the evaluation of the spatial memory of rats in a probe trial in the Morris water escape task requires a more detailed analysis.
Blokland
Arjan
A
Faculty of Psychology, Brain and Behavior Institute, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands. a.blokland@psychology.unimaas.nl
Geraerts
Elke
E
Been
Marin
M
D000818:Animals; D001070:Appetitive Behavior; D004924:Escape Reaction; D008297:Male; D018782:Maze Learning; D008568:Memory / Q000502:physiology; D011597:Psychomotor Performance; D011897:Random Allocation; D051381:Rats; D011930:Reaction Time; D013028:Space Perception; D013037:Spatial Behavior; D013550:Swimming