[Study in functional compensation of skin flap:an experimental of fast prefabricated random skin flap].
OBJECTIVE
To investigate the possibility and the limit in increasing the survival area of the random skin flap by extremely increasing the ratio of its length and width within 24 hours.


METHODS
SD rats (n = 20) were chosen for this study. The rats were randomly divided into: subject group and control one. Pre-made skin flap was prepared as design. The subject group was carried out rapid pre-fabricated skin flap formation training. No training was performed in control group. The changes in perfusion value of micro-circulation inside skin flap were monitored during the whole process, and micro-circulation parameters of the skin flap were used to evaluate whether its blood circulation network was mature or not.


RESULTS
Training of pre-made skin flap at 18th hour, the perfusion value of its micro-circulation was basically stable, Skin flap formation was finished at 24th hour. Survival area in control group was (68.25 +/- 0.18)% and in subject group was (97.25 +/- 0.24)% (P < 0.01). There was a significant difference between the two groups.


CONCLUSIONS
Within short time, it is possible to establish micro-circulation in skin flap which exceeds the limit set by traditional theory. Digitalized judgment can be used to monitor the fast formation of super-big skin flap. This method is reliable and can increase the survival rate of random skin flap.
Beijing Ji Shui Tan Hospital, Beijing 100035, China.
Jun
J
Xu
Guo-An
GA
Zhang
Shi-Ri
SR
Cui
Hong
H
Su
Hui-Ru
HR
Mi
Hao
H
Wang
Ming-Liang
ML
Zhang
D000818:Animals; D005260:Female; D008297:Male; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D012867:Skin / Q000098:blood supply* / Q000378:metabolism*; D016038:Skin Transplantation; D013524:Surgical Flaps; D013997:Time Factors