Initial management of complex pediatric disorders: prunebelly syndrome, posterior urethral valves.
Prunebelly syndrome and posterior urethral valves are conditions of detrusor dysfunction associated with antenatal urethral obstruction. The resultant severe hydroureteronephrosis and renal dysplasia initiate a sequence potentially leading to renal failure. This article reviews clinical features and explores neonatal evaluation and treatment for both conditions. A comprehensive approach to initial management aimed at optimal renal preservation and bladder rehabilitation is proposed.
Strand
William R
WR
Section of Pediatric Urology, University of Texas Southwestern Medical Center, Suite 1401, 6300 Harry Hines Boulevard, Dallas, TX 75235, USA. wstrand@childrens.com
D003456:Cryptorchidism / Q000209:etiology; D006801:Humans; D006869:Hydronephrosis / Q000209:etiology / Q000628:therapy; D007231:Infant, Newborn; D008297:Male; D011535:Prune Belly Syndrome / Q000175:diagnosis / Q000628:therapy*; D016216:Ultrasonography, Prenatal; D014521:Urethra / Q000002:abnormalities*; D014555:Urination Disorders / Q000209:etiology / Q000628:therapy; D014563:Urodynamics