Effects of 24 h ultra-marathon on biochemical and hematological parameters.
OBJECTIVE
To analyze detailed changes in hematology and biochemistry tests parameters before and after a long-distance race in ultramarathon runners.


METHODS
Blood samples of 11 participants were obtained for standard analysis before, immediately after, two days after and nine days after the 2002 International Ultra-marathon 24 h Race and the International Association of Ultrarunners (IAU) Asia 24 h Championship.


RESULTS
Total bilirubin (BIL-T), direct bilirubin (BIL-D), alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT) and lactate dehydrogenase (LDH) increased statistically significantly (P<0.05) the race. Significant declines (P<0.05) in red blood cell (RBC), hemoglobin (Hb) and hematocrit (Hct) were detected two days and nine days d after the race. 2 d after the race, total protein (TP), concentration of albumin and globulin decreased significantly. While BIL, BIL-D and ALP recovered to their original levels. High-density lipoprotein cholesterol (HDL-C) remained unchanged immediately after the race, but it was significantly decreased on the second and ninth days after the race.


CONCLUSIONS
Ultra-marathon running is associated with a wide range of significant changes in hematological parameters, several of which are injury related. To provide appropriate health care and intervention, the man who receives athletes on high frequent training program high intensity training programs must monitor their liver and gallbladder function.
Department of Physical Education, Chinese Culture University, Taipei 111, Taiwan, China.
Huey-June
HJ
Wu
Kung-Tung
KT
Chen
Bing-Wu
BW
Shee
Huan-Cheng
HC
Chang
Yi-Jen
YJ
Huang
Rong-Sen
RS
Yang
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D001798:Blood Proteins / Q000378:metabolism; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D005293:Ferritins / Q000097:blood; D006400:Hematocrit; D006454:Hemoglobins; D006801:Humans; D007501:Iron / Q000097:blood; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010807:Physical Endurance / Q000502:physiology*; D012420:Running / Q000502:physiology*; D014280:Triglycerides / Q000097:blood
D001798:Blood Proteins; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D006454:Hemoglobins; D014280:Triglycerides; D005293:Ferritins; D007501:Iron; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D001663:Bilirubin