Oxygen saturation-dependent absorption and scattering of blood.
We report on the scattering properties of oxygenated and deoxygenated whole blood from 250 to 1000 nm. We determine the complex refractive index of oxygenated and deoxygenated hemoglobin using a Kramers-Kronig analysis and optical coherence tomography measurements. Combining these data with Mie theory, the scattering properties are calculated. The strong oxygen saturation dependent scattering effects should be taken into account in the data analysis of optical oxymetry.
Laser Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Dirk J
DJ
Faber
Maurice C G
MC
Aalders
Egbert G
EG
Mik
Brett A
BA
Hooper
Martin J C
MJ
van Gemert
Ton G
TG
van Leeuwen
D000042:Absorption; D000818:Animals; D001703:Biophysics / Q000379:methods*; D001769:Blood / Q000378:metabolism*; D001790:Blood Physiological Phenomena; D006454:Hemoglobins / Q000737:chemistry*; D015233:Models, Statistical; D010092:Oximetry; D010100:Oxygen / Q000737:chemistry*; D013223:Statistics as Topic; D013552:Swine; D041623:Tomography, Optical Coherence / Q000379:methods*
D006454:Hemoglobins; D010100:Oxygen