Atypical teratoid/rhabdoid tumor: an unusual presentation.
Atypical teratoid/ rhabdoid tumor (AT/RT) of the central nervous system is a rare, highly aggressive malignancy of infancy. Although it is reported infrequently in the literature, it has often been histologically confused with a primitive neuroectodermal tumor (PNET)/medulloblastoma (MB) but has a much worse prognosis. We present an infant with two AT/RT tumors, one suprasellar in location and the other within the vermis without evidence of tumor elsewhere. What makes this case unusual is that there were two separate lesions in different cranial compartments, with no evidence of subarachnoid seeding. In addition, the lesions had different magnetic resonance imaging (MRI) characteristics even though they were histologically the same.
Department of Neurosurgery, The Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1136, Annenberg 8-06, New York, NY 10029-6574, USA. chirag.gandhi@mssm.edu
Chirag D
CD
Gandhi
Mark D
MD
Krieger
J Gordon
JG
McComb
D005260:Female; D006801:Humans; D007223:Infant; D015192:Infratentorial Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011859:Radiography; D018335:Rhabdoid Tumor / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D015173:Supratentorial Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D013724:Teratoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery