Vascular endothelial function and plasma homocysteine levels in Behcet's disease.
The purpose of the present study was to test endothelial function and to determine if plasma homocysteine levels are associated with endothelial injury in patients with Behcet's disease (BD). Flow-mediated dilation in patients with BD was smaller than that of control subjects (p = 0.001), and mean plasma homocysteine levels in patients with BD were significantly higher (p = 0.0001). On regression analysis, only mean plasma homocysteine concentration was independently related to flow-mediated dilation (F = 5.7, p = 0.001).
Department of Cardiology, Faculty of Medicine, Inonu University, Turgut Ozal Medical Center, Malatya, Turkey. rozdemir@inonu.edu.tr
Ramazan
R
Ozdemir
Irfan
I
Barutcu
Alpay T
AT
Sezgin
Nusret
N
Acikgoz
Necip
N
Ermis
Ali Metin
AM
Esen
Ergun
E
Topal
Emrah
E
Bariskaner
Ibrahim
I
Ozerol
D000328:Adult; D001528:Behcet Syndrome / Q000000981:diagnostic imaging / Q000503:physiopathology*; D001783:Blood Flow Velocity / Q000502:physiology; D001916:Brachial Artery / Q000000981:diagnostic imaging / Q000503:physiopathology; D015150:Echocardiography, Doppler; D004730:Endothelium, Vascular / Q000000981:diagnostic imaging / Q000503:physiopathology*; D005260:Female; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D014664:Vasodilation / Q000502:physiology
D006710:Homocysteine