Accidental tenfold overdose of propofol in a 6-month old infant undergoing elective craniosynostosis repair.
We report a 6-month-old male infant undergoing elective craniosynostosis repair who accidentally received a tenfold dose of propofol over a 4-h operative period. Myocardial dysfunction was observed after nearly 3 h of infusion; this could not solely be explained by the propofol overdose.
Department of Anaesthesiology, University of Cologne, Joseph-Stelzmann-Str. 9, 50931 Cologne, Germany.
B
B
Patermann
S
S
Buzello
M
M
Dück
M
M
Paul
S
S
Kampe
D018686:Anesthetics, Intravenous / Q000008:administration & dosage* / Q000009:adverse effects; D002303:Cardiac Output, Low / Q000139:chemically induced; D003398:Craniosynostoses / Q000601:surgery*; D062787:Drug Overdose; D006801:Humans; D007223:Infant; D007431:Intraoperative Complications; D008297:Male; D008508:Medication Errors; D015742:Propofol / Q000008:administration & dosage* / Q000009:adverse effects
D018686:Anesthetics, Intravenous; D015742:Propofol