Total synthesis of (+)-scyphostatin, a potent and specific inhibitor of neutral sphingomyelinase.
Inoue
Munenori
M
Sagami Chemical Research Center, 2743-1 Hayakawa, Ayase, Kanagawa 252-1193, Japan.
Yokota
Wakako
W
Murugesh
Modachur G
MG
Izuhara
Takashi
T
Katoh
Tadashi
T
D000577:Amides / Q000138:chemical synthesis*; D001203:Ascomycota / Q000737:chemistry; D003510:Cyclohexanes / Q000138:chemical synthesis; D053138:Cyclohexenes; D011753:Pyrones / Q000138:chemical synthesis*; D013108:Sphingomyelin Phosphodiesterase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013109:Sphingomyelins / Q000378:metabolism; D013237:Stereoisomerism
D000577:Amides; D003510:Cyclohexanes; D053138:Cyclohexenes; D011753:Pyrones; D013109:Sphingomyelins; C121123:scyphostatin; C052568:cyclohexene; D013108:Sphingomyelin Phosphodiesterase