Erinacol (cyatha-3,12-dien-14beta-ol) and 11-O-acetylcyathin A3, new cyathane metabolites from an erinacine Q-producing Hericium erinaceum.
In our search for new cyathane metabolites related to the biosynthesis of erinacine Q in Hericium erinaceum, we isolated a novel cyatha-3,12-dien-14beta-ol named erinacol together with known 11-O-acetylcyathatriol (the erinacine Q aglycon) and new metabolite 11-O-acetylcyathin A(3) from the mycelial extract. The structure of each compound was determined by spectral methods. Possible biosynthetic relationships of these metabolites are discussed from their structural features.
Kenmoku
Hiromichi
H
Course of the Science of Bioresources, The United Graduate School of Agricultural Sciences, Iwate University (Yamagata University), Wakaba-cho, Tsuruoka 997-8555, Japan.
Tanaka
Kazumi
K
Okada
Katsuhide
K
Kato
Nobuo
N
Sassa
Takeshi
T
D001487:Basidiomycota / Q000378:metabolism*; D004224:Diterpenes / Q000737:chemistry* / Q000378:metabolism*
C497666:11-O-acetylcyathin A3; D004224:Diterpenes; C497667:cyatha-3,12-dien-14beta-ol; C497675:cyathane; C468147:erinacine Q