Hepatic mesenchymal hamartoma with translocation involving chromosome band 19q13.4: a recurrent abnormality.
We report a case of mesenchymal hamartoma of the liver in an 8-month-old male child, in which the cytogenetic analysis revealed a balanced translocation, t(11;19)(q13;q13.4). This is the fifth description of a cytogenetic abnormality in mesenchymal hamartoma and is similar to the four cases reported previously in that one of the breakpoints involved chromosome band 19q13.4.
Rakheja
Dinesh
D
Department of Pathology, Children's Medical Center of Dallas and the University of Texas Southwestern Medical Center, 1935 Motor Street, Dallas, TX 75235, USA.
Margraf
Linda R
LR
Tomlinson
Gail E
GE
Schneider
Nancy R
NR
D002871:Chromosome Banding; D002880:Chromosomes, Human, Pair 11 / Q000235:genetics* / Q000648:ultrastructure; D002888:Chromosomes, Human, Pair 19 / Q000235:genetics* / Q000648:ultrastructure; D006222:Hamartoma / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D006498:Hepatectomy; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D008297:Male; D008648:Mesoderm / Q000473:pathology; D014178:Translocation, Genetic / Q000235:genetics*