[Use of peptide bioregulators in intoxication with the herbicide 2,4-dichlorophenoxyacetic acid].
The paper shows it promising to use peptide bioregulators--fractions obtained from the cattle immune system (thymus, spleen, and lymph nodes) during immunotherapy for intoxication experimentally caused by the herbicide 2,4-dichlorophenoxyacetic acid. Oral administration of the fractions in a dose of 0.1 mg/kg body weight eliminated the suppressive effect of the herbicide on murine cellular and humoral immune reactions, which manifested by the recovery of the studied parameters to those in control animals.
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Lebedeva
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Zhamsaranova
D015084:2,4-Dichlorophenoxyacetic Acid / Q000506:poisoning*; D000284:Administration, Oral; D000818:Animals; D002417:Cattle; D003627:Data Interpretation, Statistical; D006540:Herbicides / Q000506:poisoning*; D007155:Immunologic Factors / Q000008:administration & dosage / Q000627:therapeutic use*; D007167:Immunotherapy; D008198:Lymph Nodes / Q000276:immunology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D010455:Peptides / Q000008:administration & dosage / Q000627:therapeutic use*; D011041:Poisoning / Q000628:therapy; D013154:Spleen / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology; D013997:Time Factors
D006540:Herbicides; D007155:Immunologic Factors; D010455:Peptides; D015084:2,4-Dichlorophenoxyacetic Acid