Colonization with extraintestinal pathogenic Escherichia coli among nursing home residents and its relationship to fluoroquinolone resistance.
In a cross-sectional fecal prevalence survey involving 49 residents of a Veterans Affairs nursing home, 59% of subjects were colonized with extraintestinal pathogenic Escherichia coli (ExPEC), 22% were colonized with adhesin-positive E. coli, and 51% were colonized with fluoroquinolone-resistant E. coli. Among 80 unique isolates, adhesins correlated negatively and aerobactin correlated positively with fluoroquinolone resistance.
Section of Infectious Diseases, Veterans Affairs Medical Center, University and Woodland Ave., Philadelphia, PA 19104, USA. joel.maslow@med.va.gov
Joel N
JN
Maslow
Ebbing
E
Lautenbach
Thomas
T
Glaze
Warren
W
Bilker
James R
JR
Johnson
D018829:Adhesins, Bacterial / Q000378:metabolism; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism; D004927:Escherichia coli Infections / Q000382:microbiology*; D005243:Feces / Q000382:microbiology; D024841:Fluoroquinolones / Q000494:pharmacology; D006801:Humans; D006877:Hydroxamic Acids / Q000378:metabolism; D009735:Nursing Homes; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014481:United States; D014493:United States Department of Veterans Affairs; D037521:Virulence Factors
D018829:Adhesins, Bacterial; D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D006877:Hydroxamic Acids; D037521:Virulence Factors; C031819:aerobactin