Hip arthropathy in a patient with primary hemochromatosis: MR imaging findings with pathologic correlation.
Arthropathy is a major clinical manifestation in primary hemochromatosis, typically affecting the metacarpophalangeal joints. Hip arthropathy is not uncommon, with radiologic features resembling osteoarthritis or calcium pyrophosphate dihydrate (CPPD) crystal deposition disease. We describe the MR imaging findings of the hip in a patient with severe hip arthropathy and primary hemochromatosis and correlate them with the histopathologic findings. MR imaging showed severe degenerative changes, with large subchondral cysts and subchondral sclerosis in the femoral head and acetabulum. There was conspicuous correlation between MR imaging and pathologic findings of the resected femoral head. However, MR imaging failed to reveal intra-articular iron.
Department of Radiology, Veterans Affairs Medical Center, University of California, 3350 La Jolla Village Drive, San Diego, CA 92161, USA. opapakon@med.uoc.gr
Olympia
O
Papakonstantinou
Aurea V R
AV
Mohana-Borges
Loretta
L
Campell
Debra
D
Trudell
Parviz
P
Haghighi
Donald
D
Resnick
D006432:Hemochromatosis / Q000150:complications*; D006621:Hip Joint / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000209:etiology* / Q000473:pathology*