GE PETtrace cyclotron as a neutron source for boron neutron capture therapy.
This paper discusses the use of a General Electric PETtrace cyclotron as a neutron source for boron neutron capture therapy. In particular, the standard PETtrace (18)O target is considered. The resulting dose from the neutrons emitted from the target is evaluated using the Monte Carlo radiation transport code MCNP at different depths in a brain phantom. MCNP-simulated results are presented at 1, 2, 3, 4, 5, 6, 7, and 8 cm depth inside this brain phantom. Results showed that using a PETtrace cyclotron in the current configuration allows treating tumors at a depth of up to 4 cm with reasonable treatment times. Further increase of a beam current should significantly improve the treatment time and allow treating tumors at greater depths.
Department of Nuclear Engineering, Texas A&M University, College Station, USA. abosko@tamu.edu
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Bosko
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Zhilchenkov
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Reece
D016754:Boron Neutron Capture Therapy / Q000295:instrumentation* / Q000706:statistics & numerical data; D001932:Brain Neoplasms / Q000532:radiotherapy; D017357:Cyclotrons / Q000706:statistics & numerical data; D004867:Equipment Design; D005214:Fast Neutrons / Q000627:therapeutic use; D006801:Humans; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D011880:Radiotherapy Planning, Computer-Assisted / Q000706:statistics & numerical data