A new twist in the hijacking of the actin-nucleating machinery.
Many microbial pathogens have evolved specific adaptations to harness the host cell actin cytoskeleton. The understanding of these mechanisms reveals a striking level of complexity and diversity in the strategies utilized by different pathogens to module actin dynamics.
Section of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536, USA.
Maria
M
Lara-Tejero
Jorge E
JE
Galán
D000199:Actins / Q000378:metabolism*; D003599:Cytoskeleton / Q000378:metabolism; D004927:Escherichia coli Infections / Q000378:metabolism*; D019453:Escherichia coli O157 / Q000235:genetics / Q000378:metabolism / Q000472:pathogenicity; D044404:Genomic Islands; D006801:Humans; D009419:Nerve Tissue Proteins / Q000378:metabolism; D051317:Wiskott-Aldrich Syndrome Protein, Neuronal
D000199:Actins; D009419:Nerve Tissue Proteins; C495771:WASL protein, human; D051317:Wiskott-Aldrich Syndrome Protein, Neuronal