Reactive perforating collagenosis associated with scabies in a diabetic.
Reactive perforating collagenosis (RPC) in adults commonly manifests in patients with diabetes mellitus. Pruritus and consequent induced scratching have been identified as the bases for the evolution of this skin disease. We present the unusual case of a 55-year-old female diabetic with characteristic umbilicated skin lesions and a long history of scabies. Histology from a crusty nodule revealed transepidermal elimination of collagen. Following antiscabietic treatment, two courses of oral doxycycline demonstrated beneficial effects in controlling the perforating skin disorder.
Department of Dermatology, Klinikum Dortmund gGmbH, and University of Witten/Herdecke, Beurhausstrasse 40, D-44137 Dortmund, Germany. t.brinkmeier@derma.de
T
T
Brinkmeier
R A
RA
Herbst
P J
PJ
Frosch
D003095:Collagen Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D003920:Diabetes Mellitus; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D035002:Lower Extremity; D008875:Middle Aged; D011537:Pruritus / Q000209:etiology; D012532:Scabies / Q000150:complications / Q000175:diagnosis* / Q000473:pathology