Regioselective formation of six- and seven-membered ring by intramolecular Pd-catalyzed amination of N-allyl-anthranilamides.
A divergent synthesis of quinazolin-4-ones and 1,4-benzodiazepin-5-ones by Pd(II)-catalyzed intramolecular amination of tosylated N-allyl-anthranilamides is described. Both kinds of products were available in high yields depending on the different reaction conditions.
Beccalli
Egle M
EM
Istituto di Chimica Organica "A. Marchesini", Facoltà di Farmacia, Università di Milano, via Venezian 21, 20133 Milano, Italy.
Broggini
Gianluigi
G
Paladino
Giuseppe
G
Penoni
Andrea
A
Zoni
Caterina
C