A 4-year-old girl with autosomal dominant polycystic kidney disease complicated by a ruptured intracranial aneurysm.
In patients with autosomal dominant polycystic kidney disease (ADPKD), intracranial aneurysms (ICAs) are extrarenal manifestations and may result in serious and potentially fatal outcome following rupture. Although ICAs are a well-known complication of ADPKD, nearly all cases of ICA occurring in the context of ADPKD are adults. Here, we report the case of a Japanese girl with ADPKD who developed a subarachnoid haemorrhage (SAH) due to a ruptured ICA at the age of 4 years.


CONCLUSIONS
This report is intended to raise awareness that the use of noninvasive screening techniques such as three-dimensional CT angiography or magnetic resonance angiography to detect intracranial aneurysms should also be performed in paediatric patients with autosomal dominant polycystic kidney disease.
Department of Paediatrics, Nara Medical University, 840 Shijo-cho, 634-8522, Kashihara City, Nara, Japan.
Satomi
S
Kubo
Mitsuru
M
Nakajima
Kazuyoshi
K
Fukuda
Misato
M
Nobayashi
Toshisuke
T
Sakaki
Katsuya
K
Aoki
Yoshihiko
Y
Hirao
Akira
A
Yoshioka
D017542:Aneurysm, Ruptured / Q000209:etiology*; D001488:Basilar Artery / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D002648:Child; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000209:etiology*; D016891:Polycystic Kidney, Autosomal Dominant / Q000150:complications*; D013345:Subarachnoid Hemorrhage / Q000209:etiology