[Effect of Escherichia coli endotoxin on thymus-dependent activation of T-immunity system and expression of lymphocyte endotoxin receptors in adolescents with reccurent bronchitis].
Endotoxin-dependent direct inhibition of functional activity of T-cell immunity and biological activity of thymus factors was revealed in patients with recurrent chronic bronchitis and with systemic endoxinemia. The findings are considered by authors as an important pathogenetic mechanism inhibiting stable regression of inflammation in bronchopulmonary system in juvenile patients with recurrent chronic bronchitis. The correction of systemic endoxinemia in such patients is pathophysiologicaly substantiated.
Slobozhan
L I
LI
D001991:Bronchitis / Q000150:complications / Q000276:immunology* / Q000378:metabolism; D002648:Child; D019446:Endotoxemia / Q000150:complications / Q000276:immunology* / Q000378:metabolism; D004927:Escherichia coli Infections / Q000150:complications / Q000276:immunology* / Q000378:metabolism; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D008213:Lymphocyte Activation / Q000276:immunology; D011971:Receptors, Immunologic / Q000096:biosynthesis*; D012008:Recurrence; D013601:T-Lymphocytes / Q000276:immunology* / Q000378:metabolism; D013950:Thymus Gland / Q000276:immunology*
D011971:Receptors, Immunologic; C048071:endotoxin receptor