Viruses and tumours--an update.
In the 40 years since the publication of the article by Harris (Eur J Cancer 1965, 1, 183-188), considerable progress has been made towards the understanding of the contribution of infectious agents to the development of tumours. It is estimated that 15-20% of human malignancies may have an infectious aetiology. This article attempts to summarise the current level of our knowledge with respect to tumour-associated viruses, and to place this in the context of the earlier article by Harris (Eur J Cancer 1965, 1, 183-188).
Centre for Infectious Diseases, University of Edinburgh, R(D)SVS, Summerhall, Edinburgh EH9 1QH, UK. stalbot@ed.ac.uk
Simon J
SJ
Talbot
Dorothy H
DH
Crawford
D000951:Antigens, Neoplasm; D002051:Burkitt Lymphoma / Q000821:virology; D004266:DNA Virus Infections / Q000235:genetics; D004267:DNA Viruses / Q000235:genetics; D016147:Genes, Tumor Suppressor; D015316:Genetic Therapy / Q000009:adverse effects; D005822:Genetic Vectors; D006526:Hepatitis C / Q000175:diagnosis; D006801:Humans; D007938:Leukemia / Q000821:virology; D009369:Neoplasms / Q000821:virology*; D009857:Oncogenes; D009858:Oncogenic Viruses / Q000302:isolation & purification; D012190:Retroviridae / Q000235:genetics; D012192:Retroviridae Infections / Q000150:complications; D012514:Sarcoma, Kaposi / Q000175:diagnosis; D014412:Tumor Virus Infections / Q000821:virology*
D000951:Antigens, Neoplasm