Cavernous sinus thrombosis presenting with diplopia in an allogeneic bone marrow transplant recipient.
Although neurological complications are common in patients undergoing allogeneic bone marrow transplant (alloBMT), cavernous sinus thrombosis (CST) has rarely been described. An allograft recipient is described who presented with diplopia and developed CST in the early post-transplant period likely caused by a filamentous fungus. Clinical course and serial radiological studies of this patient are described and correlated with autopsy findings.
Department of Medical Oncology and Hematology, Princess Margaret Hospital/University Health Network, Toronto, Ontario, Canada. vikas.gupta@uhn.on.ca
Vikas
V
Gupta
Anne
A
Keller
William
W
Halliday
Stephen
S
Sanche
Wanda
W
Hassegawa
Hans
H
Messner
Thomas
T
Kiss
Jeffrey
J
Lipton
D000328:Adult; D001344:Autopsy; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002341:Carotid Artery Thrombosis; D020226:Cavernous Sinus Thrombosis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D004172:Diplopia / Q000209:etiology*; D017809:Fatal Outcome; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009181:Mycoses / Q000150:complications / Q000209:etiology; D014184:Transplantation, Homologous