Do-it-yourself tiling: dendritic growth in the absence of homotypic contacts.
Many subtypes of neurons are precisely arranged with little overlap of their dendritic arbors, which has been suggested to arise due to homotypic dendritic repulsion. In this issue of Neuron, Lin et al. demonstrate that subtypes of retinal ganglion cells establish normal dendritic field sizes and morphologies in the absence of contact with cells of the same class.
Logan
Mary A
MA
Department of Neurobiology and Anatomy, University of Utah, 20 North 1900 East, Salt Lake City, Utah 83142, USA.
Vetter
Monica L
ML
D000818:Animals; D002450:Cell Communication / Q000502:physiology*; D002455:Cell Division / Q000502:physiology; D003712:Dendrites / Q000502:physiology*; D006801:Humans; D012165:Retinal Ganglion Cells / Q000166:cytology / Q000502:physiology