Hepatic mesenchymal hamartoma with translocation involving chromosome band 19q13.4: a recurrent abnormality.
We report a case of mesenchymal hamartoma of the liver in an 8-month-old male child, in which the cytogenetic analysis revealed a balanced translocation, t(11;19)(q13;q13.4). This is the fifth description of a cytogenetic abnormality in mesenchymal hamartoma and is similar to the four cases reported previously in that one of the breakpoints involved chromosome band 19q13.4.
Department of Pathology, Children's Medical Center of Dallas and the University of Texas Southwestern Medical Center, 1935 Motor Street, Dallas, TX 75235, USA.
Dinesh
D
Rakheja
Linda R
LR
Margraf
Gail E
GE
Tomlinson
Nancy R
NR
Schneider
D002871:Chromosome Banding; D002880:Chromosomes, Human, Pair 11 / Q000235:genetics* / Q000648:ultrastructure; D002888:Chromosomes, Human, Pair 19 / Q000235:genetics* / Q000648:ultrastructure; D006222:Hamartoma / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D006498:Hepatectomy; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D008297:Male; D008648:Mesoderm / Q000473:pathology; D014178:Translocation, Genetic / Q000235:genetics*