Lichen amyloidosus with subepidermal blister formation.
We report a 74-year-old man who presented with multiple, itchy keratotic papules or plaques on the trunk and extremities. Erosions and vesicles were also intermingled on keratotic lesions. Histopathologic examination of biopsy specimens taken from three different lesions showed a subepidermal blister with amyloid deposits in the dermal papillae. No systemic disease or involvement of other organs was detected. The clinical and histological findings were compatible with a bullous variant of lichen amyloidosus. Although bullous amyloidosis has been reported in systemic amyloidosis, bullous lesions associated with lichen amyloidosus are very rare.
Kuroda
Kei
K
Department of Dermatology, National Defence Medical College, 3-2 Namiki, Tokorozawa 359-8513, Japan. kuroda@me.ndmc.ac.jp
Mizoguchi
Masako
M
D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis* / Q000473:pathology; D001415:Back; D003937:Diagnosis, Differential; D006801:Humans; D007866:Leg; D017512:Lichenoid Eruptions / Q000175:diagnosis* / Q000473:pathology; D008297:Male