Simultaneous occurrence of Hodgkin disease and tuberculosis: report of three cases.
Tuberculosis (TB) has been described in association with malignancies including Hodgkin disease (HD). We report three cases of simultaneous occurrence of TB and HD. In two of these cases clinical symptoms improved after TB treatment was instituted and before HD was diagnosed. Fever recurrence in one case and persistence of mediastinal lymphadenopathy in the other, however, prompted consideration of an additional diagnosis. Interestingly, in one these two patients, both TB and HD diagnosis were obtained from the same lymph node. Since both diseases share many symptoms and signs, physicians faced with initial therapeutic failure when caring for HD and TB patients should be aware of the possibility of the simultaneous occurrence of both diseases.
Costa
Luciano J M
LJ
Division of Infectious Disease, University of Sao Paulo, Sao Paulo, Brazil.
Gallafrio
Christina T
CT
França
Francisco O S
FO
del Giglio
Auro
A
D000328:Adult; D005260:Female; D006689:Hodgkin Disease / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D014376:Tuberculosis / Q000150:complications*; D014388:Tuberculosis, Lymph Node; D014397:Tuberculosis, Pulmonary / Q000150:complications