Is gastric cancer preventable?
Gastric cancer is a major health burden worldwide and prevention is the most promising strategy to control the disease. The available scientific evidence indicates that curing Helicobacter pylori infection results in a modest retardation of the precancerous process but does not prevent all cancers. Individuals at the highest risk should be cured of their infection and monitored endoscopically to detect dysplasia and "early" cancer, amenable to successful treatment.
Louisiana State University, Department of Pathology, LSU Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA. correa@lsuhsc.edu
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D016481:Helicobacter Infections / Q000150:complications* / Q000188:drug therapy; D016480:Helicobacter pylori; D006801:Humans; D011230:Precancerous Conditions / Q000382:microbiology / Q000517:prevention & control; D016032:Randomized Controlled Trials as Topic; D013274:Stomach Neoplasms / Q000382:microbiology / Q000517:prevention & control*