Impetigo herpetiformis in a primigravida: successful treatment with etretinate.
Impetigo herpetiformis (IH) is a rare dermatosis which usually occurs during the third trimester of pregnancy. It is characterized by acute erythematosquamous plaques covered with tiny superficial pustules in a herpetiform distribution with less likely mucus membranes involvement. It can be associated with constitutional symptom s such as fever, chills, nausea, vomiting and diarrhea. Impetigo herpetiformis can cause serious complications to the mother and fetus which include: maternal hypocalcemia leading to delirium, convulsions, and tetany in the mother, and placental insufficiency leading to still birth, neonatal death or fetal abnormalities. Lesions are expected to disappear after birth but may recur during subsequent pregnancies at an earlier gestational age. Presented here is a case of IH occurring during the 37th week of gestation in a primigravida who failed to respond to oral steroid but successfully cleared with oral etretinate.
Department of Dermatology, King Faisal University, College of Medicine and Medical Sciences. consultant@dermatologyclinics.net
Iqbal A
IA
Bukhari
D003874:Dermatitis Herpetiformis / Q000175:diagnosis / Q000188:drug therapy*; D003937:Diagnosis, Differential; D005050:Etretinate / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000188:drug therapy*; D014581:Urticaria / Q000175:diagnosis
D007641:Keratolytic Agents; D005050:Etretinate