[The effect of the extracellular bacteriolytic enzymes of Lysobacter sp. on gram-negative bacteria].
The effect of the extracellular bacteriolytic enzymes of Lysobacter sp. on gram-negative bacteria was studied. These enzymes were found to be able to hydrolyze the peptidoglycan that was isolated from the gram-negative bacteria, the hydrolysis being completely inhibited by the cell wall lipopolysaccharide of these bacteria. The native cells of the gram-negative bacteria became susceptible to the bacteriolytic enzymes after the permeability of the outer membrane of the cells had been altered by treating them with polymyxin B.
Begunova
E A
EA
Stepnaia
O A
OA
Tsfasman
I M
IM
Kulaev
I S
IS
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001433:Bacteriolysis; D002473:Cell Wall / Q000737:chemistry; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000502:physiology; D006868:Hydrolysis; D008070:Lipopolysaccharides / Q000494:pharmacology; D010447:Peptide Hydrolases / Q000302:isolation & purification / Q000378:metabolism*; D010457:Peptidoglycan / Q000378:metabolism; D011112:Polymyxin B / Q000494:pharmacology; D044166:Xanthomonadaceae / Q000201:enzymology*
D000900:Anti-Bacterial Agents; D008070:Lipopolysaccharides; D010457:Peptidoglycan; C060332:lysoamidase; D010447:Peptide Hydrolases; D011112:Polymyxin B