Solvents and malignancy.
Despite the number of substances that fall under the rubric of solvent, only a few are considered to be potential carcinogens. The purpose of this article is to provide readers with an overview of the cancer data that exist for a number of solvents currently in commercial use. These solvents include chloroform, carbon tetrachloride, methylene chloride (dichloromethane) trichloroethylene, tetrachloroethylene (perchloroethylene), and 1,4-dioxane. Although benzene also would be considered a solvent, the data concerning its carcinogenic potential are presented in another article in this issue and are not discussed in this article.
BBL Sciences, 2940 Kerry Forest Parkway, Suite 102, Tallahassee, FL 32309-6824, USA. mw1@bbl-inc.com
Michael J
MJ
Wernke
John D
JD
Schell
D000818:Animals; D002251:Carbon Tetrachloride / Q000009:adverse effects; D002725:Chloroform / Q000009:adverse effects; D004146:Dioxanes / Q000009:adverse effects; D004781:Environmental Exposure / Q000009:adverse effects*; D006801:Humans; D008752:Methylene Chloride / Q000009:adverse effects; D009369:Neoplasms / Q000139:chemically induced* / Q000453:epidemiology; D012997:Solvents / Q000009:adverse effects*; D014241:Trichloroethylene / Q000009:adverse effects
D004146:Dioxanes; D012997:Solvents; D014241:Trichloroethylene; D008752:Methylene Chloride; D002725:Chloroform; D002251:Carbon Tetrachloride; C025223:1,4-dioxane