Initial management of complex pediatric disorders: prunebelly syndrome, posterior urethral valves.
Prunebelly syndrome and posterior urethral valves are conditions of detrusor dysfunction associated with antenatal urethral obstruction. The resultant severe hydroureteronephrosis and renal dysplasia initiate a sequence potentially leading to renal failure. This article reviews clinical features and explores neonatal evaluation and treatment for both conditions. A comprehensive approach to initial management aimed at optimal renal preservation and bladder rehabilitation is proposed.
Section of Pediatric Urology, University of Texas Southwestern Medical Center, Suite 1401, 6300 Harry Hines Boulevard, Dallas, TX 75235, USA. wstrand@childrens.com
William R
WR
Strand
D003456:Cryptorchidism / Q000209:etiology; D006801:Humans; D006869:Hydronephrosis / Q000209:etiology / Q000628:therapy; D007231:Infant, Newborn; D008297:Male; D011535:Prune Belly Syndrome / Q000175:diagnosis / Q000628:therapy*; D016216:Ultrasonography, Prenatal; D014521:Urethra / Q000002:abnormalities*; D014555:Urination Disorders / Q000209:etiology / Q000628:therapy; D014563:Urodynamics