[Conservative treatment of knee osteoarthritis].
The management of knee osteoarthritis requires a combination of both non-pharmacological and pharmacological treatment modalities. Non-pharmacological therapies include patient education, lifestyle modification, weight reduction, regular exercise, physiotherapy and the use of orthopaedic appliances (canes, insoles, braces). Pharmacological treatment includes the application of non-opioid or opioid analgetics, non-steroidal anti-inflammatory drugs or coxibes and intra-articular glucocorticoids. Glucosamin, chondroitin sulphate and hyaluronic acid are safe and provide symptomatic relief while their therapeutic effects remain uncertain.
Orthopädische Universität- und Poliklinik, Universitätskliniken des Saarlandes, Homburg.
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D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D018771:Arthralgia / Q000209:etiology / Q000517:prevention & control*; D004035:Diet Therapy / Q000379:methods*; D005081:Exercise Therapy / Q000379:methods*; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D020370:Osteoarthritis, Knee / Q000188:drug therapy / Q000534:rehabilitation / Q000628:therapy*; D010166:Palliative Care / Q000379:methods*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'
D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D005938:Glucocorticoids