Optimization of wedelolactone accumulation in shoot cultures of Eclipta alba.
Influence of different environmental factors on accumulation of wedelolactone, a potential anti-hepatotoxic principle of E. alba in shoot cultures was investigated. A significant increase in the content of wedelolactone due to kinetin treatment, temperature change and photoperiod alteration in shoot cultures was observed. Incorporation of phenylalanine in the medium also increased content of wedelolactone significantly in a dose-dependent manner.
Jayathirtha
M G
MG
Pharmacy Department, Faculty of Technology and Engineering, Kalabhavan, The M S University of Baroda, Baroda 390 001, India.
Mishra
S H
SH
D002855:Chromatography, Thin Layer; D003374:Coumarins / Q000378:metabolism*; D036601:Eclipta / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D018520:Plant Shoots / Q000378:metabolism*
D003374:Coumarins; C051122:wedelolactone