Treatment issues in pediatric gastric adenocarcinoma.
Gastric adenocarcinoma is a rare diagnosis in children. Modern treatment includes chemotherapy, radiotherapy, and surgery and has evolved over the past decade. The authors report a case of an 8-year-old girl with gastric adenocarcinoma. The case will be followed by a brief discussion of the presentation, current management guidelines, and prognosis of this rare pediatric entity.
Department of Pediatric Surgical Oncology, M.D. Anderson Cancer Center, Houston, TX, USA.
Matthew T
MT
Harting
Martin L
ML
Blakely
Cynthia E
CE
Herzog
Kevin P
KP
Lally
Jaffer A
JA
Ajani
Richard J
RJ
Andrassy
D000713:Anastomosis, Roux-en-Y; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D018279:Carcinoma, Signet Ring Cell / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery*; D017115:Catheter Ablation; D017024:Chemotherapy, Adjuvant; D002648:Child; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D000077143:Docetaxel; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D005743:Gastrectomy; D005756:Gastritis / Q000150:complications; D016481:Helicobacter Infections / Q000150:complications; D016480:Helicobacter pylori; D006801:Humans; D000077146:Irinotecan; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D008197:Lymph Node Excision; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D009386:Neoplastic Syndromes, Hereditary; D010180:Pancreatectomy; D011379:Prognosis; D011838:Radiation-Sensitizing Agents / Q000008:administration & dosage; D018714:Radiotherapy, Adjuvant; D012074:Remission Induction; D012086:Reoperation; D013156:Splenectomy; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics / Q000532:radiotherapy / Q000601:surgery*; D043823:Taxoids / Q000008:administration & dosage
D011838:Radiation-Sensitizing Agents; D043823:Taxoids; D000077143:Docetaxel; D000077146:Irinotecan; D002945:Cisplatin; D005472:Fluorouracil; D002166:Camptothecin