[Recurrent bouts of fever accompanied by abdominal pain and emesis].
A 34 year-old Turkish patient was admitted to hospital several times with the same symptoms of abdominal pain, fever up to 39.2 degrees C and vomiting. The diagnosis always was an acute attack of chronic pancreatitis. The inflammation scores in the blood were high and he had a moderate increase in pancreatic enzymes. He always got well in a few days on a strict diet and regime of analgesics. Taking these symptoms and his ethnic affiliation into consideration, differential diagnosis should include familial Mediterranean fever (FMF). Therapy with colchicine should be initiated even if genetic testing does not reveal the mutation characteristics for FMF. Immediate and consistent therapy helps to avoid amyloid nephropathy as the most dangerous complication of this disease.
Innere Medizin, Klinik Bad Windsheim. blassneck@gmx.de
K
K
Blassneck
G
G
Nusko
J
J
Benninger
E G
EG
Hahn
I A
IA
Harsch
D015746:Abdominal Pain / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D000328:Adult; D017772:Amyloid Neuropathies / Q000209:etiology / Q000517:prevention & control; D002908:Chronic Disease; D003078:Colchicine / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004035:Diet Therapy / Q000379:methods; D010505:Familial Mediterranean Fever / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D005335:Fever of Unknown Origin / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D020022:Genetic Predisposition to Disease / Q000209:etiology; D006801:Humans; D008297:Male; D010195:Pancreatitis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D012008:Recurrence; D014839:Vomiting / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy
D003078:Colchicine