A new twist in the hijacking of the actin-nucleating machinery.
Many microbial pathogens have evolved specific adaptations to harness the host cell actin cytoskeleton. The understanding of these mechanisms reveals a striking level of complexity and diversity in the strategies utilized by different pathogens to module actin dynamics.
Lara-Tejero
Maria
M
Section of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536, USA.
Galán
Jorge E
JE
D000199:Actins / Q000378:metabolism*; D003599:Cytoskeleton / Q000378:metabolism; D004927:Escherichia coli Infections / Q000378:metabolism*; D019453:Escherichia coli O157 / Q000235:genetics / Q000378:metabolism / Q000472:pathogenicity; D044404:Genomic Islands; D006801:Humans; D009419:Nerve Tissue Proteins / Q000378:metabolism; D051317:Wiskott-Aldrich Syndrome Protein, Neuronal
D000199:Actins; D009419:Nerve Tissue Proteins; C495771:WASL protein, human; D051317:Wiskott-Aldrich Syndrome Protein, Neuronal