Half-sandwich arene ruthenium(II)-enzyme complex.
The 1.6 [Angstrom] X-ray crystal structure of [(eta(6)-p-cymene)Ru(lysozyme)Cl(2)], the first of a half-sandwich complex of a protein, shows selective ruthenation of Nepsilon of the imidazole ring of His15.
Institute of Cell and Molecular Biology, Michael Swann Building, University of Edinburgh, Mayfield Road, Edinburgh, UK.
Iain W
IW
McNae
Katy
K
Fishburne
Abraha
A
Habtemariam
Tina M
TM
Hunter
Michael
M
Melchart
Fuyi
F
Wang
Malcolm D
MD
Walkinshaw
Peter J
PJ
Sadler
D001120:Arginine / Q000737:chemistry; D001224:Aspartic Acid / Q000737:chemistry; D018360:Crystallography, X-Ray; D006639:Histidine / Q000737:chemistry; D007093:Imidazoles / Q000737:chemistry; D008956:Models, Chemical; D009097:Multienzyme Complexes / Q000737:chemistry*; D009113:Muramidase / Q000737:chemistry* / Q000494:pharmacology; D009942:Organometallic Compounds / Q000737:chemistry* / Q000494:pharmacology; D011506:Proteins / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry* / Q000494:pharmacology
D007093:Imidazoles; D009097:Multienzyme Complexes; D009942:Organometallic Compounds; D011506:Proteins; D001224:Aspartic Acid; D006639:Histidine; C029899:imidazole; D012428:Ruthenium; D001120:Arginine; D009113:Muramidase