Whole-body fluorine-18 fluordeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in staging of advanced uveal melanoma.
Fluorine-18 fluordeoxyglucose positron emission tomography (FDG-PET) is an useful tool in diagnosing and monitoring of malignant cutaneous melanoma. However, the feasibility and usefulness of FDG-PET in uveal melanoma is not yet established. We present a patient with suspected advanced uveal melanoma who underwent combined FDG-PET/computed tomography (CT) for staging. FDG-PET/CT images demonstrated vital intraocular tumor. Anatomical assignment of the malignancy to the choroid was possible by means of the coregistered computed tomography. Furthermore, PET revealed an unknown otherwise undetected vital liver metastasis. We conclude that combined FDG-PET/CT has potential to further improve staging and therapy planning in patients with advanced uveal melanoma.
Department of Nuclear Medicine, University Hospital, Essen, Germany.
L S
LS
Freudenberg
A O
AO
Schueler
T
T
Beyer
G
G
Antoch
H
H
Kühl
N
N
Bornfeld
A
A
Bockisch
T
T
Egelhof
D000368:Aged; D015353:Eye Enucleation; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008545:Melanoma / Q000175:diagnosis* / Q000601:surgery; D009367:Neoplasm Staging; D019275:Radiopharmaceuticals; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed; D014604:Uveal Neoplasms / Q000175:diagnosis* / Q000601:surgery
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18