[Application of chi-square test and exact test in Hardy-Weinberg equilibrium testing].
This article review the application of chi-square test of various data handling methods and exact test in Hardy-Weinberg equilibrium testing of human genetic marker in population genetics. The importance of HWE-exact test in multiallelic system was emphasized, especially in the study of forensic VNTR and STR typing.
Huang
Dai-Xin
DX
Faculty of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030,China. huangdaixin@hotmail.com
Yang
Qing-En
QE
D000483:Alleles; D016009:Chi-Square Distribution; D005554:Forensic Medicine; D005787:Gene Frequency; D005828:Genetics, Population / Q000379:methods*; D005838:Genotype; D006801:Humans; D016013:Likelihood Functions; D008957:Models, Genetic; D015233:Models, Statistical