[Use of peptide bioregulators in intoxication with the herbicide 2,4-dichlorophenoxyacetic acid].
The paper shows it promising to use peptide bioregulators--fractions obtained from the cattle immune system (thymus, spleen, and lymph nodes) during immunotherapy for intoxication experimentally caused by the herbicide 2,4-dichlorophenoxyacetic acid. Oral administration of the fractions in a dose of 0.1 mg/kg body weight eliminated the suppressive effect of the herbicide on murine cellular and humoral immune reactions, which manifested by the recovery of the studied parameters to those in control animals.
Lebedeva
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Zhamsaranova
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D015084:2,4-Dichlorophenoxyacetic Acid / Q000506:poisoning*; D000284:Administration, Oral; D000818:Animals; D002417:Cattle; D003627:Data Interpretation, Statistical; D006540:Herbicides / Q000506:poisoning*; D007155:Immunologic Factors / Q000008:administration & dosage / Q000627:therapeutic use*; D007167:Immunotherapy; D008198:Lymph Nodes / Q000276:immunology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D010455:Peptides / Q000008:administration & dosage / Q000627:therapeutic use*; D011041:Poisoning / Q000628:therapy; D013154:Spleen / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology; D013997:Time Factors
D006540:Herbicides; D007155:Immunologic Factors; D010455:Peptides; D015084:2,4-Dichlorophenoxyacetic Acid