Problematic differential diagnosis between cerebellar liponeurocytoma and anaplastic oligodendroglioma.
A cerebellar tumour, first diagnosed as an anaplastic oligodendroglioma, received radiation therapy (45 Gy) following gross total resection. The second histological study revealed a liponeurocytoma, a benign tumour not requiring adjuvant therapy. This case emphasizes the importance of considering this diagnosis to prevent unnecessary irradiation of such rumours.
Valéry
C A
CA
Services de Neurochirurgie, Hôpital de la Pitié-Salpêtrière, Paris, France. charles.valery@psl.ap-hop-paris.fr
Sakka
L J
LJ
Poirier
J
J
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001932:Brain Neoplasms / Q000175:diagnosis*; D003937:Diagnosis, Differential; D050701:E2F6 Transcription Factor; D005260:Female; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D008067:Lipoma / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery; D008279:Magnetic Resonance Imaging; D018306:Neurocytoma / Q000175:diagnosis* / Q000532:radiotherapy / Q000601:surgery; D009837:Oligodendroglioma / Q000175:diagnosis*; D016708:Synaptophysin / Q000032:analysis; D014157:Transcription Factors / Q000032:analysis; D014746:Vimentin / Q000032:analysis
D014408:Biomarkers, Tumor; D050701:E2F6 Transcription Factor; C491744:E2F6 protein, human; D016708:Synaptophysin; D014157:Transcription Factors; D014746:Vimentin