Minimum inhibitory concentrations for 25 selected antimicrobial agents against Dichelobacter nodosus and Fusobacterium strains isolated from footrot in sheep of Portugal and Spain.
The agar dilution method was used to determine the inhibitory activity of 25 antimicrobial agents against 69 strains of Dichelobacter nodosus and 108 strains of the genus Fusobacterium, all of which were isolated from 90 clinical cases of ovine footrot between October 1998 and November 2000. In the case of the micro-organisms belonging to the genus Fusobacterium, the six beta-lactams studied (benzyl penicillin, ampicillin, cloxacillin, cefadroxil, cefuroxime and cephalexine) proved to be, in general, the most effective antimicrobial agents. Chloramphenicol, clindamycin and doxycycline were also quite active against Fusobacterium spp. With regard to the 69 strains of D. nodosus tested, the levels of resistance remain low.
Cátedra de Microbiología e Inmunología, Departamento de Medicina y Sanidad Animal, Facultad de Veterinaria, Avda. de la Universidad s/n, 10071 Cáceres, Spain.
R
R
Jiménez
S
S
Píriz
E
E
Mateos
S
S
Vadillo
D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology* / Q000627:therapeutic use; D020376:Dichelobacter nodosus / Q000187:drug effects* / Q000302:isolation & purification; D024881:Drug Resistance, Bacterial; D005535:Foot Rot / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D005673:Fusobacterium / Q000187:drug effects* / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D011174:Portugal / Q000453:epidemiology; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D013030:Spain / Q000453:epidemiology
D000890:Anti-Infective Agents