A remarkably efficient coupling of acid chlorides with alkynes in water.
[reaction: see text] A highly effective direct coupling of acid chloride with terminal alkynes catalyzed by PdCl(2)(PPh(3))(2)/CuI together with a catalytic amount of sodium lauryl sulfate as the surfactant and K(2)CO(3) as the base provided ynones in high yields in water.
Department of Chemistry, Tulane University, New Orleans, Louisiana 70118, USA.
Liang
L
Chen
Chao-Jun
CJ
Li