Coronary vasospasm and myocardial infarction induced by oral sumatriptan.
Coronary vasospasm is well documented as a side effect of injectable subcutaneous forms of sumatriptan; only one such case has been reported so far with oral ingestion of sumatriptan in a patient with underlying coronary artery disease. This report describes a case of coronary vasospasm induced by oral sumatriptan even in normal coronary arteries. Physicians and patients should be aware of a small and unpredictable risk of the serious cardiac side effects of this drug.
Division of Cardiology, University of Missouri, Columbia, MO, USA. wassons@health.missouri.edu
Sanjeev
S
Wasson
Vinod K S
VK
Jayam
D000284:Administration, Oral; D000328:Adult; D002533:Cerebral Angiography / Q000379:methods; D003324:Coronary Artery Disease / Q000188:drug therapy / Q000503:physiopathology; D003329:Coronary Vasospasm / Q000139:chemically induced* / Q000503:physiopathology; D004562:Electrocardiography / Q000379:methods; D005260:Female; D006801:Humans; D009203:Myocardial Infarction / Q000139:chemically induced* / Q000503:physiopathology; D018170:Sumatriptan / Q000009:adverse effects*; D014662:Vasoconstrictor Agents / Q000009:adverse effects*
D014662:Vasoconstrictor Agents; D018170:Sumatriptan