Multiple sclerosis with severe pain and allodynia alleviated by oral ketamine.
The objective of this study is to determine the effect of oral ketamine on pain and allodynia associated with multiple sclerosis. A 60-year-old woman with multiple sclerosis was referred to our clinic because of severe pain and allodynia. Oral ketamine was started at a dose of 20 mg once a day and increased to twice a day. Oral ketamine was effective in the treatment of the pain and allodynia associated with multiple sclerosis.
Sakai
Tetsuya
T
Department of Anesthesiology, Nagasaki University School of Medicine, Sakamoto, Japan. tscat@fb3.so-net.ne.jp
Tomiyasu
Shiro
S
Ono
Takeshi
T
Yamada
Hiroyuki
H
Sumikawa
Koji
K
D000284:Administration, Oral; D000700:Analgesics / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006930:Hyperalgesia / Q000188:drug therapy* / Q000209:etiology; D007649:Ketamine / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications*; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D010147:Pain Measurement / Q000379:methods
D000700:Analgesics; D007649:Ketamine