Case report: clinical and serological evaluation of echinococcosis of the spine.
A 53-year-old male with a severe destructive lesion of the L4 vertebral body caused by an Echinococcus granulosus hydatid cyst was studied. He underwent surgery twice, and was treated continuously with albendazole, followed by albendazole combined with praziquantel. Specific anti-echinococcal immunoglobulin (Ig) G, IgG4, and IgE activities before and after surgery were further determined. In spite of long-term chemotherapeutic treatment combined with surgery, no eradication of the disease was achieved.
Laboratory of Parasitic Diseases, Department of Microbiology and Immunology, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel. jelon@bgumail.bgu.ac.il
J
J
El-On
L
L
Ben-Noun
Z
Z
Galitza
N
N
Ohana
D015766:Albendazole / Q000627:therapeutic use*; D000871:Anthelmintics / Q000627:therapeutic use*; D000923:Anticestodal Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D004443:Echinococcosis / Q000097:blood / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D011223:Praziquantel / Q000627:therapeutic use*; D012008:Recurrence; D013122:Spinal Diseases / Q000097:blood / Q000188:drug therapy* / Q000601:surgery; D017211:Treatment Failure
D000871:Anthelmintics; D000923:Anticestodal Agents; D011223:Praziquantel; D015766:Albendazole