[Bone mineral density and 17 beta-estradiol correlation in postmenopausal women].
BACKGROUND
With the increased life-expectancy reached during 20th century, women will spend a very important part of their lives in the estrogenic deficiency state accompanying menopause.


OBJECTIVE
To detect serum 17beta-estradiol levels, bone mineral density values, and to see the correlation between both parameters as well as with postmenopausal period.


METHODS
A transversal study with ambulatory, community-dwelling postmenopausal women from Oaxaca de Juárez, Oax. was performed.


RESULTS
We studied 70 women with spontaneous menopause, medium values were: age, 55.9 +/- 5.4 yr; menopause age, 48 +/- 3 yr; postmenopausal period, 7.9 +/- 5.3 yr; body mass index, 28.3 +/- 5.4, and serum 17beta-estradiol by radioimmunoassay, 62.78 +/- 25.83 pg/mL. Quantitative calcaneous ultrasound was used to measure bone mineral density and we found 30 women with normal level (-1.0 to 1.4 SD), 29 with osteopenia (-1.1 to -2.3 SD) and only 2 subjects with osteoporosis (-2.7 to 2.8 SD).


CONCLUSIONS
Statistical analysis shows that bone mineral density and postmenopausal period were significantly correlated (p<0.05) as well as serum 17beta-estradiol levels with postmenopausal period; nevertheless, no correlation between bone mineral density and serum 17beta-estradiol or body mass index (p>0.05) was found. On the other hand, it is remarkable high serum 17beta-estradiol levels found in this group, related with postmenopausal status. These latter results are different from those reported in the literature.
Facultad de Medicina y Cirugía de la Universidad Autónoma Benito Juárez de Oaxaca, México. becar2003@hotmail.com
Beatriz Eugenia
BE
Cárdenas Morales
Eduardo
E
Pérez Campos
Noé
N
Gatica Valdez
D000368:Aged; D015992:Body Mass Index; D001835:Body Weight; D015519:Bone Density / Q000502:physiology*; D004958:Estradiol / Q000097:blood* / Q000502:physiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000097:blood* / Q000473:pathology; D017698:Postmenopause / Q000502:physiology*
D004958:Estradiol