[Expression of chemokine-like factor 2(CKLF2) mRNA in rat myocardium with hypertrophy].
OBJECTIVE
To investigate the expression of CKLF2 mRNA in the rat myocardium with hypertrophy.


METHODS
Rat abdominal aorta was constricted by operation to make myocardium hypertrophy in the hypertrophy group and the control group was subjected to the sham-operation. The CKLF2 mRNA expressions were tested by competitive polymerase chain reaction (CPCR).


RESULTS
Compared to the control-group, the expression of CKLF2 mRNA of hypertrophy-group significantly increased on the 17th day after operation, and decreased to the control level on the 45th day.


CONCLUSIONS
The expression of rCKLF2 mRNA in rat myocardium with hypertrophy significantly increased in early days of hypertrophy.
Department of cardiology, Peking University First Hospital, Beijing 100034,China.
Hong-kun
HK
Ren
Tao
T
Hong
Jie
J
Jiang
Yan-jun
YJ
Gong
Zhi-jian
ZJ
Wang
Ding-fang
DF
Bu
Ai-ru
AR
Zhou
D000818:Animals; D001483:Base Sequence; D006332:Cardiomegaly / Q000235:genetics*; D018925:Chemokines / Q000235:genetics*; D015870:Gene Expression; D008297:Male; D008969:Molecular Sequence Data; D009206:Myocardium / Q000378:metabolism*; D012333:RNA, Messenger / Q000235:genetics; D051381:Rats; D017208:Rats, Wistar
C474963:CKLF2 protein, rat; D018925:Chemokines; D012333:RNA, Messenger