Human immunodeficiency virus type 1 and other viral co-infections among young heterosexual men and women in Argentina.
Infections with hepatitis C virus, (HCV), hepatitis B virus (HBV), and human T lymphotropic type I/II (HTLV-I/II) virus are commonly found in patients infected with human immunodeficiency virus type 1 (HIV-1). We conducted a seroepidemiologic study among 174 HIV-positive heterosexuals in Buenos Aires, Argentina in 1999. Evidence of exposure to HCV, HBV, and HTLV-I/II was found in 32%, 17%, and 5%, respectively. A higher prevalence of HBV infection was observed among males (33%) compared with females (12%; P < 0.05). Among women, a prior history of a sexually transmitted infection, injecting drug use (IDU), having had more than five lifetime sex partners, and having exchanged sex-for-goods were significantly associated with HCV infection, whereas an IDU history, syringe sharing, and having exchanged sex-for-goods were found to be associated with HBV infection. Among men, an IDU history and syringe/needle sharing were significantly associated with HCV infection. The IDU-related and sexual transmission of hepatitis viruses constitute a significant problem among young, HIV-infected, heterosexuals in Argentina.
de los Angeles Pando
María
M
Centro Nacional de Referencia para el SIDA, Buenos Aires, Argentina. mpando@fmed.uba.ar
Biglione
Mirna M
MM
Toscano
Mauro Fernández
MF
Rey
Jorge A
JA
Russell
Kevin L
KL
Negrete
Monica
M
Gianni
Silvia
S
Martinez-Peralta
Liliana
L
Salomon
Horacio
H
Sosa-Estani
Sergio
S
Montano
Silvia M
SM
Olson
James G
JG
Sanchez
José L
JL
Carr
Jean K
JK
Avila
Maria M
MM
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D001118:Argentina / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology*; D015497:HIV-1 / Q000276:immunology; D015490:HTLV-I Infections / Q000150:complications / Q000453:epidemiology*; D015491:HTLV-II Infections / Q000150:complications / Q000453:epidemiology*; D016174:Hepacivirus / Q000276:immunology; D006509:Hepatitis B / Q000150:complications / Q000453:epidemiology*; D006515:Hepatitis B virus / Q000276:immunology; D006526:Hepatitis C / Q000150:complications / Q000453:epidemiology*; D020010:Heterosexuality; D015368:Human T-lymphotropic virus 1 / Q000276:immunology; D015367:Human T-lymphotropic virus 2 / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D016036:Seroepidemiologic Studies
D000914:Antibodies, Viral