Drosophila lifespan enhancement by exogenous bacteria.
We researched the lifespan of Drosophila under axenic conditions compared with customary procedure. The experiments revealed that the presence of bacteria during the first week of adult life can enhance lifespan, despite unchanged food intake. Later in life, the presence of bacteria can reduce lifespan. Certain long-lived mutants react in different ways, indicating an interplay between bacteria and longevity-enhancing genes.
Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
Ted
T
Brummel
Alisa
A
Ching
Laurent
L
Seroude
Anne F
AF
Simon
Seymour
S
Benzer
D000367:Age Factors; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004330:Drosophila / Q000187:drug effects / Q000235:genetics / Q000382:microbiology* / Q000502:physiology; D005856:Germ-Free Life / Q000502:physiology*; D008136:Longevity / Q000187:drug effects / Q000502:physiology*
D000900:Anti-Bacterial Agents