Unusual photophysical switching in a Ru(II) diimine DNA probe caused by amide functionalisation.
Whereas the complex [Ru(phen)2Medpq]2+(phen=1,10-phenanthroline; Medpq=2-methyldipyrido[3,2-f:2',3'-h]-quinoxaline) is luminescent in both aqueous and nonaqueous solutions, [Ru(phen)2dpqa]2+(2-pentylamidodipyrido[3,2-f:2',3'-h]-quinoxaline) does not emit in water but does so strongly in organic solvents or when bound to DNA--suggesting its use as a photochemical and photophysical probe for nucleic acids.
O'Donoghue
Karen A
KA
Department of Chemistry, Trinity College, Dublin 2, Ireland.
Kelly
John M
JM
Kruger
Paul E
PE
D000577:Amides / Q000737:chemistry*; D015342:DNA Probes / Q000737:chemistry*; D007097:Imines / Q000737:chemistry*; D049408:Luminescent Agents / Q000737:chemistry; D008956:Models, Chemical; D015394:Molecular Structure; D012428:Ruthenium / Q000737:chemistry*
D000577:Amides; D015342:DNA Probes; D007097:Imines; D049408:Luminescent Agents; D012428:Ruthenium