[Monomers for oligonucleotide synthesis with linkers carrying reactive residues: II. Synthesis of phosphoamidites based of uridine and cytosine and containing a linker with methoxyoxalamide groups in position 2'].
A convenient preparative synthesis of 2'-amino-2'-deoxyuridine was developed. Starting from 2'-amino-2'-deoxyuridine and 2'-amino-2'-deoxycytidine, monomers for the phosphoamidite oligonucleotide synthesis were obtained that carry a linker with methoxyoxalamide groups in position 2'. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2004, vol. 30, no. 3; see also http://www.maik.ru.
Vasil'eva
S V
SV
Abramova
T V
TV
Ivanova
T M
TM
Shishkin
G V
GV
Silnikov V N
D000577:Amides / Q000737:chemistry*; D003841:Deoxycytidine / Q000031:analogs & derivatives*; D003857:Deoxyuridine / Q000031:analogs & derivatives* / Q000737:chemistry*; D009841:Oligonucleotides / Q000138:chemical synthesis* / Q000737:chemistry; D009943:Organophosphorus Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010072:Oxamic Acid / Q000737:chemistry*
C410434:2'-amino-2'-deoxyuridine; D000577:Amides; D009841:Oligonucleotides; D009943:Organophosphorus Compounds; D003841:Deoxycytidine; D010072:Oxamic Acid; D003857:Deoxyuridine