title: [Molecular epidemiologic analysis of nosocomocal infection due to TEIC resistant MRSA strains].
abstract: We performed epidemiologic study of 109 strains of methicillin resistant Staphylococcus aureus (MRSA) which were detected in our hospital. Of these strains, 6 strains showed resistant to Teicoplanin (TEIC) which MIC level were between 4 to 8microg/mL. All of them showed some phenotype, such as type II of coagulase, type A of enterotoxin, and were producing TSST-1. Genotype analysis by PFGE also showed that those strains ware identical. From analyzing the spreading rout of these TEIC resistant MRSA, we speculate that they first were in ICU ward, then spread all over the hospital carried by the stuff cross-working ICU and other units of hospital.
authors.affiliation: Department of Clinical Laboratory, Clinical Research Institute, National Hospital Organaization Kyushu Medical Center.
authors.forename: Makiko
authors.initials: M
authors.lastname: Kiyosuke
authors.forename: Megumi
authors.initials: M
authors.lastname: Takayanagi
authors.forename: Zenzo
authors.initials: Z
authors.lastname: Nagasawa
authors.forename: Akira
authors.initials: A
authors.lastname: Koguchi
authors.forename: Ariaki
authors.initials: A
authors.lastname: Nagayama
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001427:Bacterial Toxins / Q000096:biosynthesis; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D016521:Electrophoresis, Gel, Pulsed-Field; D004768:Enterotoxins / Q000096:biosynthesis; D005260:Female; D006801:Humans; D008297:Male; D016106:Methicillin Resistance; D008875:Middle Aged; D017720:Molecular Epidemiology; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D018089:Superantigens / Q000096:biosynthesis; D017334:Teicoplanin / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal; D017334:Teicoplanin