title: Successful treatment of infected vascular prosthetic grafts in the groin using conservative therapy with povidone-iodine solution.
abstract: Four cases of infected vascular prosthetic graft in the groin successfully treated with povidone-iodine solution using a conservative approach are described here. In all patients the same technique was used. After complete debridement, the prosthetic graft in the groin was completely exposed. The wound was cleansed with hydrogen peroxide and then dressed with gauze soaked in 1:10 sterile water-diluted povidone-iodine solution. The dressings were changed twice a day. The patients were supplemented by systemic therapy of an appropriate antibiotic. All patients were observed in the intensive care unit. In all patients this treatment method led to control of infection and healing of the wound. Thus, it was not necessary to remove the prosthetic graft and patients were spared a major surgical intervention. At follow-up, the prosthetic grafts remain patent without any signs of recurrence of infection.
authors.affiliation: Department of Surgery, Charles University Medical School Teaching Hospital, Hradec Kralove, Czech Republic. rene.voboril@seznam.cz
authors.forename: Rene
authors.initials: R
authors.lastname: Voboril
authors.forename: Jana
authors.initials: J
authors.lastname: Weberova
authors.forename: Hradec
authors.initials: H
authors.lastname: Kralove
mesh_terms: D000368:Aged; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D001157:Arterial Occlusive Diseases / Q000601:surgery; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D004756:Enterobacteriaceae Infections / Q000209:etiology / Q000628:therapy; D005260:Female; D005263:Femoral Artery / Q000473:pathology / Q000601:surgery; D006119:Groin / Q000601:surgery*; D006801:Humans; D007083:Iliac Artery / Q000473:pathology / Q000601:surgery; D035002:Lower Extremity / Q000098:blood supply / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery / Q000473:pathology / Q000601:surgery; D011206:Povidone-Iodine / Q000627:therapeutic use*; D016459:Prosthesis-Related Infections / Q000209:etiology* / Q000628:therapy*; D013290:Streptococcal Infections / Q000209:etiology* / Q000628:therapy*
chemical_list: D000891:Anti-Infective Agents, Local; D011206:Povidone-Iodine