title: Recent advances in the treatment of opiate addiction.
abstract: Although addiction to heroin and other opiates is a major public health issue in the United States and many other countries, advances in pharmacologic and nonpharmacologic treatment have been made. Some of these advances represent a major shift from traditional treatment philosophies, whereas others are characterized by more subtle, though important, improvements. This review discusses recent advances in opiate-addiction treatment in the context of three main domains: the use of buprenorphine and buprenorphine/naloxone in an office-based paradigm, psychosocial treatment and the addressing of medical and psychiatric comorbidity, and harm reduction strategies.
authors.affiliation: Behavioral Health Service (116), Veterans Affairs Medical Center, Room B-228, University and Woodland Avenues, Philadelphia, PA 19104, USA. fudala_p@mail.trc.upenn.edu
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Fudala
authors.forename: George W
authors.initials: GW
authors.lastname: Woody
mesh_terms: D002047:Buprenorphine / Q000627:therapeutic use*; D015897:Comorbidity; D004359:Drug Therapy, Combination; D006801:Humans; D001523:Mental Disorders / Q000209:etiology / Q000628:therapy; D009270:Naloxone / Q000627:therapeutic use*; D009292:Narcotic Antagonists / Q000627:therapeutic use*; D009819:Office Visits; D009293:Opioid-Related Disorders / Q000188:drug therapy*; D011613:Psychotherapy
chemical_list: D009292:Narcotic Antagonists; D009270:Naloxone; D002047:Buprenorphine