title: First two cases of living related liver transplantation with complicated anatomy of blood vessels in Beijing.
abstract: OBJECTIVE
  Living related liver transplantation (LRLT) has been developed in response to the paediatric organ donor shortage. Though it has been succeeded in many centers worldwide, the safety of the donor is still a major concern, especially in donors with anatomy variation. We succeeded in performing the first two cases of living related liver transplantation with complicated anatomy of blood vessels as a way to overcome cadaveric organ shortage in Beijing.
  
  
  METHODS
  Two patients, with congenital liver fibrosis and congenital biliary atresia were performed with living donor liver transplantation in our hospital and then followed up from November 12 to December 13, 2001. The two living donors, mother and father, were healthy aged 34 and 35 years. One right lobe (segment V, VI, VII, VIII) and one left lateral lobe (segment II and III) were used. The grafts weighed 394 g and 300 g. The ratio of graft weight to the standard liver volume (SLV) of donors was 68% and 27%. The graft weight to recipient body weight ratio was 3.2% and 4.4%. The graft weight to recipient estimated standard liver mass (ESLM) ratio was 63% and 85%. The two donors had complicated blood vessel variation.
  
  
  RESULTS
  Two patients undergone living donor liver transplantation had good results. Abnormal liver function with high bilirubin level appeared in a few days after operation, but liver function returned to normal one month after operation with bilirubin level almost decreased to near normal. No bleeding, thrombosis, infection and bile leakage occurred. One had an acute rejection and recovered. The two donors recovered in two weeks. One had slight fever because of a little collection in abdomen and recovered after paracentesis and drainage.
  
  
  CONCLUSIONS
  Living donor liver transplantation has been proved to be a good way that offers a unique opportunity of getting a timely liver graft as a response to shortage of pediatric donors, though it could be a technically difficult operation if there is anatomical variation.
authors.affiliation: Department of Surgery, The First Hospital, Peking University, Beijing 100034, China.
authors.forename: Wen-Han
authors.initials: WH
authors.lastname: Wu
authors.forename: Yuan-Lian
authors.initials: YL
authors.lastname: Wan
authors.forename: Long
authors.initials: L
authors.lastname: Lee
authors.forename: Yin-Mo
authors.initials: YM
authors.lastname: Yang
authors.forename: Yan-Ting
authors.initials: YT
authors.lastname: Huang
authors.forename: Chao-Long
authors.initials: CL
authors.lastname: Chen
authors.forename: Sheung-Tat
authors.initials: ST
authors.lastname: Fan
mesh_terms: D000328:Adult; D002648:Child; D002681:China; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D007223:Infant; D008102:Liver Circulation; D008103:Liver Cirrhosis / Q000151:congenital / Q000601:surgery; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D020858:Tissue and Organ Harvesting / Q000379:methods; D016896:Treatment Outcome