(Bu3Sn)2-TBAF: a new combination reagent for the reduction and deuteration of aryl bromides and iodides.
The combination of (Bu(3)Sn)(2) and TBAF has been shown to reduce aromatic bromides and iodides in excellent yields under mild conditions. When the residual water in TBAF is exchanged for D(2)O, the halogen is replaced by a deuterium atom.
Harrowven
David C
DC
Department of Chemistry, University of Southampton, Southampton, SO17 1BJ, UK. dch2@soton.ac.uk
Guy
Ian L
IL
Nunn
Michael I T
MI