Radiosurgery and radiotherapy for sacral tumors.
Sacral tumors represent a small subset of spinal lesions and typically include chordomas, metastases, other primary bone tumors, and benign schwannomas. Resection is the standard treatment for many sacral tumors, but many types of sacral lesions have the potential for recurrence after excision. In these cases, adjuvant radiotherapy is often beneficial. Although conventional radiotherapy plays an important role in the management of spinal lesions, the radiation doses required for adequate local control of many sacral lesions generally exceed the tolerance doses of normal tissues, thus limiting its definitive role in the management of sacral tumors. Recent advances in the field of stereotactic radiosurgery have allowed precise targeting of the sacrum. In this report the authors review the use of these two forms of radiation treatment and their role in managing sacral tumors.
Gibbs
Iris C
IC
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA. iris.gibbs@stanford.edu
Chang
Steven D
SD
D000328:Adult; D000368:Aged; D017824:Bone Cysts, Aneurysmal / Q000532:radiotherapy; D002277:Carcinoma / Q000556:secondary / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D018212:Giant Cell Tumor of Bone / Q000532:radiotherapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000556:secondary / Q000601:surgery; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology / Q000209:etiology; D010315:Particle Accelerators; D011832:Radiation Injuries / Q000453:epidemiology / Q000209:etiology; D016634:Radiosurgery / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D011878:Radiotherapy / Q000009:adverse effects / Q000379:methods; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal / Q000009:adverse effects; D012447:Sacrum / Q000601:surgery*; D013122:Spinal Diseases / Q000532:radiotherapy; D013125:Spinal Neoplasms / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery*; D016896:Treatment Outcome