title: Antroduodenal motility in neurologically handicapped children with feeding intolerance.
abstract: BACKGROUND
  Dysphagia and feeding intolerance are common in neurologically handicapped children. The aim is to determine the etiologies of feeding intolerance in neurologically handicapped children who are intolerant of tube feedings.
  
  
  METHODS
  Eighteen neurologically handicapped children, followed in the Tube Feeding Clinic at the Children's Hospital of Wisconsin who were intolerant of gastrostomy feedings. The charts of these 18 patients were reviewed. Past medical history, diagnoses, history of fundoplication and results of various tests of gastrointestinal function including barium contrast radiography, endoscopy and antroduodenal manometry were documented.
  
  
  RESULTS
  Five of 11 children had abnormal barium upper gastrointestinal series. Seven of 14 had abnormal liquid phase gastric emptying tests. Two of 16 had esophagitis on endoscopy. All 18 children had abnormal antroduodenal motility.
  
  
  CONCLUSIONS
  In neurologically handicapped children foregut dysmotility may be more common than is generally recognized and can explain many of the upper gastrointestinal symptoms in neurologically handicapped children.
authors.affiliation: Department of Pediatrics, Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee, WI United States of America. swerlin@mail.mcw.edu
authors.forename: Steven L
authors.initials: SL
authors.lastname: Werlin
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003680:Deglutition Disorders / Q000503:physiopathology; D004386:Duodenum / Q000503:physiopathology; D005247:Feeding Behavior / Q000502:physiology*; D005260:Female; D005769:Gastrointestinal Motility / Q000502:physiology*; D041981:Gastrointestinal Tract / Q000503:physiopathology; D006801:Humans; D007223:Infant; D008297:Male; D009422:Nervous System Diseases / Q000503:physiopathology*