title: [Permanent interstitial implantation of 125I seeds for 5 cases of advanced head and neck cancer].
abstract: OBJECTIVE
  To observe the effect of 125I seeds implants in advanced head and neck cancer.
  
  
  METHODS
  Treatment fields were designed to encompass the tumor/edema volume with a 2-3 cm margin, based on assessment of diagnostic CT images, 125I seeds were inserted into there and permanent left there for brachytherapy in 5 patients with advanced head and neck cancer including recurrent oropharyngeal cancer, supraglottic cancer and occult cancer.
  
  
  RESULTS
  Local tumor were controlled evidently and the patients suffering were alleviated, but 1 case occurred skin necrosis and 1 case occurred skin necrosis combined with internal carotid rupture.
  
  
  CONCLUSIONS
  Permanent 125I implants offer useful pallition for patients with advanced recurrent head and neck cancer but need prevention fatal complication.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, First Hospital of Peking University, Beijing, 100034, China.
authors.forename: Enmin
authors.initials: E
authors.lastname: Zhao
authors.forename: Shuifang
authors.initials: S
authors.lastname: Xiao
authors.forename: Yong
authors.initials: Y
authors.lastname: Qin
authors.forename: Quangui
authors.initials: Q
authors.lastname: Wang
authors.forename: Min
authors.initials: M
authors.lastname: Guo
authors.forename: Rongfu
authors.initials: R
authors.lastname: Wang
mesh_terms: D000368:Aged; D001918:Brachytherapy / Q000379:methods*; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
chemical_list: D007457:Iodine Radioisotopes