title: Is the nasopharynx warmer in children than in adults?
abstract: Recent studies on the aetiology of the Sudden Infant Death Syndrome (SIDS) have suggested that some of these deaths are the consequence of an overwhelming inflammatory response to the production of pyrogenic toxins from bacteria colonizing the upper respiratory tract, particularly the nasopharynx. The pyrogenic toxins of Staphlococcus aureus, one of the likelier bacterial candidates, are only produced in temperatures of over 37 degrees C. This study examined nasopharyngeal temperatures in children. It is a preliminary study to develop an accurate means to measure how close to 37 degrees C the nasopharyngeal temperature lies in infants at the age when SIDS deaths occur. Following a pilot study and power calculation, measurements of nasopharyngeal temperature were made on 30 apyrexial children aged 4-10 years and 30 adults with no nasal pathology, undergoing surgery under general anaesthesia, using an accurately sited thermocouple probe. The mean temperature in children (35.64 degrees C) was significantly higher than in adults (34.01 degrees C). Comparable measurements attempted with the same subjects awake gave similar results.
authors.affiliation: Department of Otolaryngology, Lauriston Building, The Royal Infirmary, University of Edinburgh, Edinburgh, UK.
authors.forename: N C
authors.initials: NC
authors.lastname: Molony
authors.forename: A I
authors.initials: AI
authors.lastname: Kerr
authors.forename: C C
authors.initials: CC
authors.lastname: Blackwell
authors.forename: A
authors.initials: A
authors.lastname: Busuttil