Effectiveness of home-centered care through telemedicine applications for overweight and obese patients: a randomized controlled trial.
OBJECTIVE
To determine if home-centered monitoring through telemedicine has an impact on clinical characteristics, metabolic profile and quality of life in overweight and obese patients.


METHODS
Randomized controlled trial, 6-month duration.


METHODS
Tertiary care academic hospital.


METHODS
A total of 122 patients were eligible to participate as they met the inclusion criteria of increased body mass index (BMI>25 kg/m(2)), age>18 and <70 y and ability to operate electronic microdevices.


METHODS
All patients in the control group (n=77) received standard hospital care. Patients in the intervention group (n=45), additionally, measured three times a week, for 6 months, their blood pressure and body weight and transmitted them to an automated call center. These values were not shared with the patients' physician or dietician.


METHODS
Clinical (body weight, BMI, blood pressure), laboratory (fasting plasma glucose, triglycerides, HDL-cholesterol, total cholesterol) and quality of life parameters (SF-36((R)), Visual Analog Scale of European Quality-5 Dimensions, Obesity Assessment Survey). Data were analyzed in an intention-to-treat-way (last observation carried forward).


RESULTS
Drop-out rate was similar in the control and intervention groups: 12 vs 11 percent, respectively, P=NS. There were no significant differences at baseline between intervention and control groups in all main outcome parameters. There were significant decreases for patients in the intervention group in body weight (from 101.6+/-22.4 to 89.2+/-14.7 kg, P=0.002, P=0.05 vs controls at 6 months), total cholesterol (from 247.6+/-42.0 to 220.7+/-42.6 mg/dl, P=0.002, P=0.05 vs controls at 6 months) and triglycerides (from 148.4+/-35.0 to 122.3+/-31.4 mg/dl, P=0.001, P=0.01 vs controls at 6 months). Intervention group patients made a total of 1997 phone contacts. The number of phone contacts was correlated positively with Social Functioning (SF), Vitality (VT) and Mental Health (MH) scores of SF-36((R)) at baseline (r=0.48, r=0.41, r=0.41, respectively, P=0.05) but not with weight loss.


CONCLUSIONS
Home-centered, intense treatment through the use of telemedicine can be effective in improving short-term obesity outcomes.
Goulis
D G
DG
Department of Endocrinology, Hippocration General Hospital, 49 Constantinoupoleos street, 54642, Thessaloniki, Greece. dgg30@otenet.gr
Giaglis
G D
GD
Boren
S A
SA
Lekka
I
I
Bontis
E
E
Balas
E A
EA
Maglaveras
N
N
Avramides
A
A
D000328:Adult; D001794:Blood Pressure; D001835:Body Weight; D001330:Electronic Data Processing; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000628:therapy*; D011788:Quality of Life; D012044:Regression Analysis; D017216:Telemedicine / Q000379:methods*; D015431:Weight Loss