title: [Cytophagic histiocytic panniculitis: a report of 6 cases with literature review].
abstract: OBJECTIVE
  To study the clinical characteristics of cytophagic histiocytic panniculitis (CHP) and increase the understanding of CHP.
  
  
  METHODS
  Clinical data of six cases with CHP in our hospital from 1994 were presented with literature review.
  
  
  RESULTS
  (1) Six patients including five females, at a mean age of 21.8 year, suffered from the diseases for a mean period of 12.7 months; (2) The major clinical presentations included fever (6/6), subcutaneous nodules (6/6), splenomegaly (5/6) and hepatomegaly (4/6); The laboratory examinations showed elevated hepatic enzymes (4/6), coagulative dysfunction (2/6) and hemocytopenia (3/6); (3) The pathologic examinations revealed benign histiocytes that infiltrated the adipose tissues (6/6) and hemopieotic tissue (3/3), phagocytosing hemocytes; (4) Only one patient was treated with combined chemotherapy.
  
  
  CONCLUSIONS
  CHP should be considered based on its unique clinical characteristics and would be diagnosed depending on pathology. The aggressive treatment of combined chemotherapy might improve the prognosis.
authors.affiliation: Department of Rheumatology. Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.
authors.forename: Meng-tao
authors.initials: MT
authors.lastname: Li
authors.forename: Xiao-feng
authors.initials: XF
authors.lastname: Zeng
authors.forename: Feng-chun
authors.initials: FC
authors.lastname: Zhang
authors.forename: Fu-lin
authors.initials: FL
authors.lastname: Tang
mesh_terms: D000273:Adipose Tissue / Q000473:pathology; D000293:Adolescent; D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D006644:Histiocytes / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015434:Panniculitis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D011379:Prognosis