title: A new pair of CR1-like LINE and tRNA-derived SINE elements in Podarcis sicula genome.
abstract: We have identified and characterized a new pair of LINE and SINE elements, called Lucy-1 CR1-like LINE and P.s.1/SINE, respectively, in Podarcis sicula genome. The 3'-tail region in the 3' untranslated region (UTR) of Lucy-1 element is almost identical to the of P.s.1/SINE element. This identity suggests that the P.s.1/SINE element, during evolution, has gained the 3'-end sequence of the Lucy-1 element and has exclusively recruited the enzymatic machinery of its partner CR1 LINE for retroposition. Moreover, the complex molecular organization around Lucy-1 insertion site is discussed and we found that Lucy-1 insertion is associated with the calcium binding transporter gene. Our results confirm that the retrotransposons can be an additional source of genomic diversification and the evolution of the retrotransposable elements can be a vector force shaping genomes by reassorting DNA domains thus forming a new DNA arrangement.
authors.affiliation: Department of Life Science, II University of Naples, Via Vivaldi 43, 81100, Caserta, Italy.
authors.forename: Stefania
authors.initials: S
authors.lastname: Fantaccione
authors.forename: Consiglia
authors.initials: C
authors.lastname: Russo
authors.forename: Patrizia
authors.initials: P
authors.lastname: Palomba
authors.forename: Monica
authors.initials: M
authors.lastname: Rienzo
authors.forename: Giovanni
authors.initials: G
authors.lastname: Pontecorvo
mesh_terms: D000818:Animals; D001483:Base Sequence; D001665:Binding Sites / Q000235:genetics; D004247:DNA / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification; D016678:Genome; D008116:Lizards / Q000235:genetics*; D020084:Long Interspersed Nucleotide Elements / Q000235:genetics*; D008969:Molecular Sequence Data; D016254:Mutagenesis, Insertional; D012343:RNA, Transfer / Q000235:genetics*; D012357:RNA, Transfer, Lys / Q000235:genetics; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D020086:Short Interspersed Nucleotide Elements / Q000235:genetics*
chemical_list: D012357:RNA, Transfer, Lys; D004247:DNA; D012343:RNA, Transfer