title: Bioactivity of sol-gel derived organically modified silicates: part i: in vitro examination.
abstract: Bioactivity was investigated for several organically modified silicates (Ormosils) prepared through sol-gel processes. Ca(II)-free samples were biocompatible only, but Ca(II)containing samples were bioactive and deposited apatite during immersion in a simulated body fluid. The ease of silanol (Si-OH) group formation on the ormosils was considered a predominant factor controlling the bioactivity, while the effect of dissolved Ca(II) ions to increase the degree of supersaturation in the simulated body fluid is secondary.
authors.affiliation: Biomaterials Division, Faculty of Engineering, Okayama University Tsushima, Okayama-shi, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Tsuru
authors.forename: C
authors.initials: C
authors.lastname: Ohtsuki
authors.forename: A
authors.initials: A
authors.lastname: Osaka
authors.forename: T
authors.initials: T
authors.lastname: Iwamoto
authors.forename: J D
authors.initials: JD
authors.lastname: Mackenzie