title: [Effect of Sorbaria Sorbifolia extract on anti-oxidative activities in rats with precancerosis induced by diethylnitrosamine].
abstract: OBJECTIVE
  To study the effect of Sorbaria Sorbifolia extract on anti-oxidative activities in rats with precancerosis induced by diethylnitrosamine.
  
  
  METHODS
  Sorbaria sorbifolia was perfused into stomach of rats with DEN-induced precancerosis, then the biochemical indexes were investigated. The activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-PX), and the concentrations of malondialdehyde (MDA), glutathione (GSH) were investigated by colorimetric method.
  
  
  RESULTS
  Sorbaria sorbifolia extract increased SOD, GSH-PX and decreased MDA, GSH levels in serum and liver homogenate.
  
  
  CONCLUSIONS
  Sorbaria Sorbifolia extract significantly increased anti-oxidative activities in rats with precancerosis induced by diethylnitrosamine.
authors.affiliation: Department of Biochemistry & Molecular Biology, College of Medicine, Yanbian University, Yanji, Jilin Province 133000, China. zlz2913835@sina.com
authors.forename: Xue-Wu
authors.initials: XW
authors.lastname: Zhang
authors.forename: Quan
authors.initials: Q
authors.lastname: Sun
authors.forename: Ming
authors.initials: M
authors.lastname: Jin
authors.forename: Chun-Mei
authors.initials: CM
authors.lastname: Piao
authors.forename: Lian-Hua
authors.initials: LH
authors.lastname: Li
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D004052:Diethylnitrosamine / Q000008:administration & dosage; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005978:Glutathione / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism; D008099:Liver / Q000378:metabolism / Q000473:pathology; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D010084:Oxidation-Reduction / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology*; D011230:Precancerous Conditions / Q000139:chemically induced; D051381:Rats; D017208:Rats, Wistar; D027824:Rosaceae / Q000737:chemistry; D013482:Superoxide Dismutase / Q000378:metabolism
chemical_list: D000975:Antioxidants; D004365:Drugs, Chinese Herbal; D010936:Plant Extracts; D004052:Diethylnitrosamine; D008315:Malondialdehyde; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D005978:Glutathione