title: [Use of alflutop in the treatment of patients with osteoarthrosis].
abstract: The efficiency of alflutop was studied in patients with osteoarthrosis (OA) of the knee or hip joints. The examinees (n = 24) received alflutop only intramuscularly (in coxarthrosis) or intramuscularly in combination with the intraarticular injection of the agent (in knee osteoarthrosis). Physical examinations were made in control periods: before and immediately, 3, 6, and 12 months after treatment. Arthrosonography was used as an objective method for controlling the efficacy of the drug. The studies have demonstrated that alflutop substantially relieves pain, improves the function of the diseased joints in patients with OA. Arthrosonography has shown that the drug exerts an antiinflammatory effect, retards the progression of a pathological process in the joint. Alflutop has been found to be more effective in knee OA than in hip OA, which is determined by that its combined use regimen may be used in knee OA. The necessity and high efficiency of repeated courses of alflutop therapy are shown.
authors.forename: M S
authors.initials: MS
authors.lastname: Svetlova
authors.forename: V K
authors.initials: VK
authors.lastname: Ignat'ev
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000096:biosynthesis; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D014020:Tissue Extracts / Q000627:therapeutic use*
chemical_list: D000893:Anti-Inflammatory Agents; D014020:Tissue Extracts; D006820:Hyaluronic Acid