title: Aerosolized iloprost as a bridge to lung transplantation in a patient with cystic fibrosis and pulmonary hypertension.
abstract: We describe a patient with cystic fibrosis, end-stage lung disease, and secondary pulmonary hypertension in whom aerosolized iloprost was effective in lowering pulmonary artery pressure and improving functional status, thus proving successful as a bridge to lung transplantation. Inhaled iloprost may be an efficient and selective approach to treat pulmonary hypertension related to end-stage obstructive pulmonary disease.
authors.affiliation: Unit of Pediatric Cardiology, University Children's Hospital, Geneva, Switzerland.
authors.forename: Pierre
authors.initials: P
authors.lastname: Tissières
authors.forename: Laurent
authors.initials: L
authors.lastname: Nicod
authors.forename: Constance
authors.initials: C
authors.lastname: Barazzone-Argiroffo
authors.forename: Peter C
authors.initials: PC
authors.lastname: Rimensberger
authors.forename: Maurice
authors.initials: M
authors.lastname: Beghetti
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000188:drug therapy; D016285:Iloprost / Q000008:administration & dosage*; D016040:Lung Transplantation / Q000379:methods*; D009569:Nitric Oxide / Q000008:administration & dosage; D011292:Premedication; D012131:Respiratory Insufficiency / Q000209:etiology / Q000601:surgery*; D014655:Vascular Resistance / Q000187:drug effects; D014665:Vasodilator Agents / Q000008:administration & dosage*
chemical_list: D014665:Vasodilator Agents; D009569:Nitric Oxide; D016285:Iloprost