Shear-load carrying capacities of the distal rat femora after osteotomy fixed with self-reinforced polyglycolic acid and poly-L-lactic acid pins.
Distal femora of 40 rats were osteotomized and fixed with self-reinforced polyglycolide (SR-PGA) and self-reinforced polylactide (SR-PLLA) pin 2.0 mm in diameter and 15 mm in length. The shear-load carrying capacities of the osteotomized bones were compared with each other and with the intact control rat distal femora of the same age of 20 pairs. The follow-up times were 1, 3, 6, 12, 24, 36, 48, and 52 weeks. After killing all operated and control femora were examined macroscopically and radiographically. The shear-load carrying capacities reached their highest values at 24 weeks in the SR-PGA-fixed specimens, after that decreasing to the level where they remained. In the SR-PLLA-fixed specimens the strength values of the pins increased after three weeks, but there was a decrease at 24 weeks. After that the shear-load carrying capacities started to raise because of the influence of the healed osteotomy. In the control bones the shear-load carrying capacities were weaker than in the SR-PGA-and SR-PLLA-fixed specimens except at three weeks, as the osteotomies had not yet healed. During the whole follow-up period the mean shear-load carrying capacity of the SR-PGA-fixed specimens was 199.1 N, in the SR-PLLA-fixed specimens 214.6 N, the corresponding value of the control specimens being 148.2 N.
Nordström
Pia
P
Department of Orthopaedics and Traumatology, University Central Hospital, Helsinki, Finland. pia.nordstrom@hus.fi
Pohjonen
Timo
T
Törmälä
Pertti
P
Rokkanen
Pentti
P