title: Patient maintained propofol sedation for dental surgery.
abstract: OBJECTIVE
  This study evaluated a system for patients to operate a target-controlled infusion (TCI) of propofol for sedation.
  
  
  METHODS
  50 healthy adults, undergoing minor oral surgical procedures under local anaesthesia.
  
  
  METHODS
  Following instructions, patients were allowed to control their own sedation to comfortably undergo surgery.
  
  
  METHODS
  Operating conditions, degree of sedation, vital signs and patients' assessment of the technique.
  
  
  RESULTS
  Operating conditions were described as good in 47 patients and fair in 3. Optimal sedation was provided at a median target blood concentration of 2 mcg/ml (range1-3mcg/ml). 30 were sedated moderately, 16 deeply and 4 mildly. None were oversedated. The vital signs were stable in all patients. 30% of patients had injection pain and 28% became talkative. Patient satisfaction was high with 86% feeling adequately relaxed and 92% willing to use it again. 14 patients had complete and 22 had partial amnesia for the procedure.
  
  
  CONCLUSIONS
  This technique combines the benefits of target-controlled infusion with patient-controlled feedback and produces safe dental sedation.
authors.affiliation: Department of Anaesthesiology, Queen Mary Hospital, Pokfulam, Hong Kong, PR China. rodrigo@hkusua.hku.hk
authors.forename: M R C
authors.initials: MR
authors.lastname: Rodrigo
authors.forename: M G
authors.initials: MG
authors.lastname: Irwin
authors.forename: S W
authors.initials: SW
authors.lastname: Yan
authors.forename: P C Y
authors.initials: PC
authors.lastname: To
mesh_terms: D000328:Adult; D016292:Procedural Sedation / Q000379:methods* / Q000523:psychology; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D007262:Infusions, Intravenous; D008297:Male; D019647:Oral Surgical Procedures; D017060:Patient Satisfaction; D015742:Propofol / Q000008:administration & dosage*; D012646:Self Administration / Q000523:psychology; D014081:Tooth Extraction
chemical_list: D006993:Hypnotics and Sedatives; D015742:Propofol