title: Biofilm mode of growth of Streptococcus intermedius favored by a competence-stimulating signaling peptide.
abstract: Gram-positive and gram-negative bacteria use quorum sensing to coordinate population behavior. In several streptococci, quorum sensing mediated by competence-stimulating peptides (CSP) is associated with development of competence for transformation. We show here that a synthetic CSP favored the biofilm mode of growth of Streptococcus intermedius without affecting the rate of culture growth.
authors.affiliation: Department of Oral Biology, Faculty of Dentistry, University of Oslo, P.O. Box 1052, Blindern, N0316 Oslo, Norway. cpaiva@odont.uio.no
authors.forename: Fernanda C
authors.initials: FC
authors.lastname: Petersen
authors.forename: Daniele
authors.initials: D
authors.lastname: Pecharki
authors.forename: Anne A
authors.initials: AA
authors.lastname: Scheie
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology; D001426:Bacterial Proteins / Q000138:chemical synthesis* / Q000494:pharmacology*; D018441:Biofilms / Q000254:growth & development*; D004268:DNA-Binding Proteins / Q000138:chemical synthesis* / Q000494:pharmacology*; D015964:Gene Expression Regulation, Bacterial; D006133:Growth Substances / Q000138:chemical synthesis / Q000494:pharmacology; D008855:Microscopy, Electron, Scanning; D034367:Streptococcus intermedius / Q000166:cytology / Q000235:genetics* / Q000502:physiology*; D014170:Transformation, Genetic / Q000187:drug effects*
chemical_list: D001426:Bacterial Proteins; C061262:ComA protein, Bacteria; D004268:DNA-Binding Proteins; D006133:Growth Substances