title: Vein versus tragal perichondrium in stapedotomy.
abstract: OBJECTIVE
  To assess, in otosclerosis surgery, whether the vein or the tragal perichondrium in stapedotomy with interposition yields the better long-term hearing outcome.
  
  
  METHODS
  A retrospective chart review of prospectively collected audiometric data of 452 ears.
  
  
  METHODS
  Academic tertiary otology-neurotology referral center.
  
  
  METHODS
  Four hundred fifty-two stapedotomies with interposition were performed in 412 patients (bilateral in 40 patients) by the senior author (R.C.) between 1987 and 1998. A tragal perichondrium graft was used in 314 cases and a vein graft was used in 138 cases as sealing material of the oval window.
  
  
  METHODS
  Audiometric data were recorded at 4 months, at 1 year, and at 3 years after surgery after American Academy of Otolaryngology-Head and Neck Surgery guidelines, except for thresholds at 3 kHz, which were not available and which were replaced with those at 4 kHz.
  
  
  RESULTS
  There were no significant intergroup differences in initial or late postoperative hearing outcome with regard to change in the pure-tone average bone conduction and air-bone gaps, or sensorineural hearing loss. Ears treated with a vein graft showed statistically better postoperative 2-kHz air-bone gap closure (p =0.0157), but the pure-tone average air-bone gap difference was not significant. Postoperative air-bone gap closure to within 10 dB was achieved in 91% of cases in the vein group and in 76% of cases in the perichondrium group. Specific study of the bone conduction level at 4 kHz showed a sensorineural hearing loss greater than 10 dB in 8% of cases in the vein group and in 11% of cases in the perichondrium group. One case of complete sensorineural hearing loss was observed with a tragal perichondrium graft (0.22%).
  
  
  CONCLUSIONS
  These results suggest that the vein should be preferred to the tragal perichondrium in stapedotomy with interposition.
authors.affiliation: University Department of Otorhinolaryngology, Grenoble Hospital, Grenoble, France. SSchmerber@chu-grenoble.fr
authors.forename: Sébastien
authors.initials: S
authors.lastname: Schmerber
authors.forename: Olivier
authors.initials: O
authors.lastname: Cuisnier
authors.forename: Robert
authors.initials: R
authors.lastname: Charachon
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Lavieille
mesh_terms: D001301:Audiometry, Pure-Tone; D001309:Auditory Threshold; D003238:Connective Tissue / Q000637:transplantation; D004425:Ear Cartilage / Q000637:transplantation*; D005500:Follow-Up Studies; D006801:Humans; D009998:Ossicular Prosthesis; D013506:Otologic Surgical Procedures; D010040:Otosclerosis / Q000601:surgery*; D010046:Oval Window, Ear / Q000601:surgery*; D011446:Prospective Studies; D012189:Retrospective Studies; D013201:Stapes Surgery / Q000379:methods*; D014182:Transplantation, Autologous / Q000379:methods; D016896:Treatment Outcome; D014680:Veins / Q000637:transplantation*