title: Axoval neuropathy as initial manifestation of primary amyloidosis: report of a case submitted to bone marrow transplantation.
abstract: Amyloidosis is a syndrome characterized by deposition of a highly insoluble protein material in the extracellular space that may affect several organs. It may be generalized and idiopathic (primary amyloidosis). We describe the case of a 48 years-old woman with axonal neuropathy associated with proteinuria, whose final investigation resulted in diagnosis of primary amyloidosis (AL). She was submitted to autologous bone marrow transplantation. We discuss some aspects related to diagnosis of neuropathy and current treatment of AL.
authors.affiliation: Hospital Israelita Albert Einstein, Instituto de Ensino e Pesquisa Albert Einstein, São Paulo, SP, Brazil. orlandobarsottini@hotmail.com
authors.forename: Orlando G Povoas
authors.initials: OG
authors.lastname: Barsottini
authors.forename: Adriano
authors.initials: A
authors.lastname: Arantes
authors.forename: Daniel
authors.initials: D
authors.lastname: Sigulem
authors.forename: José Mauro
authors.initials: JM
authors.lastname: Kutner
authors.forename: Andreza Alice Feitosa
authors.initials: AA
authors.lastname: Ribeiro
authors.forename: Luiz A
authors.initials: LA
authors.lastname: Moura
authors.forename: Nelson
authors.initials: N
authors.lastname: Hamerschlak
mesh_terms: D017772:Amyloid Neuropathies / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D000686:Amyloidosis / Q000150:complications* / Q000473:pathology / Q000628:therapy; D016026:Bone Marrow Transplantation; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008875:Middle Aged