title: Identification of a novel HLA-DRB1*12 allele (DRB1*1210) in the Korean population.
abstract: At least 11 HLA-DRB1*12 alleles have been identified to date. We report a new HLA-DRB1*12 allele, DRB1*1210, that was identified in the Korean population. This new allele differs from HLA-DRB1*120101 by a single nucleotide at position 40 (G-->A) in exon 1 that falls within codon--16 (GTT-->ATT). This change results in a single valine to isoleucine amino acid alteration.
authors.affiliation: National Genome Research Institute, National Institute of Health, Eunpyung-gu, Seoul, South Korea.
authors.forename: E
authors.initials: E
authors.lastname: Kim
authors.forename: E J
authors.initials: EJ
authors.lastname: Lee
authors.forename: Y H
authors.initials: YH
authors.lastname: Lim
authors.forename: J Y
authors.initials: JY
authors.lastname: Lee
authors.forename: I S
authors.initials: IS
authors.lastname: Koh
authors.forename: K
authors.initials: K
authors.lastname: Kimm
authors.forename: G E
authors.initials: GE
authors.lastname: Ji
authors.forename: K
authors.initials: K
authors.lastname: Kwack
mesh_terms: D000483:Alleles; D019943:Amino Acid Substitution / Q000235:genetics*; D001483:Base Sequence; D005091:Exons / Q000235:genetics*; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D007723:Korea; D008969:Molecular Sequence Data
chemical_list: D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains