title: [Investigation of an outbreak of acute diarrhea caused by Human calicivirus].
abstract: BACKGROUND
  To survey a diarrhea outbreak in Guangan city and analyze the cause of the disease.
  
  
  METHODS
  The population enrolled in the surveillance came from four different settings and was randomly sampled. Stool specimens collected from diarrhea patients were tested ordinarily for enteric bacteria and further examined for viral pathogens with PAGE, ELISA and RT-PCR.
  
  
  RESULTS
  In total, 4,567 persons were surveyed, among them 942 had acute diarrhea (prevalence 20.63%). The incidence was higher in rural area (28.6%) than in urban area (19.6%) (chi-square =22.29, P less than 0.005) with a peak in May 10 through 25 four human caliciviruses were detected from stool specimens by ELISA and RT-PCR in specimens from 4 and 1 patients, respectively.
  
  
  CONCLUSIONS
  Human calicivirus probably was the cause of this diarrhea outbreak in Guangan city.
authors.affiliation: Guangan Hygiene and Antiepidemic Station, Sichuan Province, Guangan 638000, China.
authors.forename: Wen-zhang
authors.initials: WZ
authors.lastname: Li
authors.forename: Hua-ping
authors.initials: HP
authors.lastname: Xie
authors.forename: Hai-yan
authors.initials: HY
authors.lastname: Wu
authors.forename: Dao-yun
authors.initials: DY
authors.lastname: Zhou
authors.forename: Li-shu
authors.initials: LS
authors.lastname: Zheng
authors.forename: Yun-shan
authors.initials: YS
authors.lastname: Cai
authors.forename: You-ling
authors.initials: YL
authors.lastname: Kang
authors.forename: Xi
authors.initials: X
authors.lastname: Jiang
authors.forename: Zhao-yin
authors.initials: ZY
authors.lastname: Fang
mesh_terms: D000208:Acute Disease / Q000453:epidemiology; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D017250:Caliciviridae Infections / Q000453:epidemiology* / Q000821:virology; D002648:Child; D002681:China / Q000453:epidemiology; D003967:Diarrhea / Q000453:epidemiology* / Q000821:virology*; D004196:Disease Outbreaks; D005243:Feces / Q000821:virology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D029322:Norovirus / Q000302:isolation & purification*; D055815:Young Adult