title: The systemic inflammatory response, performance status and survival in patients undergoing alpha-interferon treatment for advanced renal cancer.
abstract: The prognostic value of C-reactive protein, compared with ECOG performance status (ECOG-ps), in patients receiving alpha-interferon treatment for advanced renal cancer was assessed in 58 patients. In all, 55 patients died on follow-up. On multivariate analysis with ECOG-ps and C-reactive protein entered as covariates, only C-reactive protein was a significant independent predictor of survival (HR 2.03, 95% CI 1.09-3.80, P=0.026).
authors.affiliation: University Department of Surgery, Royal Infirmary, Glasgow, G31 2ER, UK.
authors.forename: E
authors.initials: E
authors.lastname: Bromwich
authors.forename: D C
authors.initials: DC
authors.lastname: McMillan
authors.forename: G W A
authors.initials: GW
authors.lastname: Lamb
authors.forename: P A
authors.initials: PA
authors.lastname: Vasey
authors.forename: M
authors.initials: M
authors.lastname: Aitchison
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002097:C-Reactive Protein / Q000032:analysis*; D002292:Carcinoma, Renal Cell / Q000188:drug therapy* / Q000276:immunology* / Q000473:pathology; D005260:Female; D006304:Health Status; D006801:Humans; D007249:Inflammation; D016898:Interferon-alpha / Q000627:therapeutic use*; D007680:Kidney Neoplasms / Q000188:drug therapy* / Q000276:immunology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D016898:Interferon-alpha; D002097:C-Reactive Protein