title: Taking stock: from chasing occlusal contacts to vulnerability alleles.
abstract: Over the past 70 years, temporomandibular disorders (TMDs) have been subject to shifts in conceptual understanding. Unable to account for disease patterns, the mismatch between case assignment and treatment need, and very different interventions producing similar treatment outcomes (except for the risk to patients), emerging theories make persuasive arguments in support of alternative explanations.
authors.affiliation: Brotman Pain Center, Dental School, University of Maryland, 666 W. Baltimore Street, Baltimore, MD 21201, USA. cstohler@dental.umaryland.edu
authors.forename: Christian S
authors.initials: CS
authors.lastname: Stohler
mesh_terms: D000483:Alleles; D019943:Amino Acid Substitution / Q000235:genetics; D002394:Catechol O-Methyltransferase / Q000235:genetics; D003766:Dental Occlusion; D003937:Diagnosis, Differential; D004198:Disease Susceptibility; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D008715:Methionine / Q000235:genetics; D020380:Needs Assessment; D012307:Risk Factors; D013705:Temporomandibular Joint Disorders / Q000145:classification / Q000209:etiology* / Q000235:genetics; D016896:Treatment Outcome; D014633:Valine / Q000235:genetics
chemical_list: D008715:Methionine; D002394:Catechol O-Methyltransferase; D014633:Valine