Pyridoxine-dependent seizures and microcephaly.
Pyridoxine dependency is a rare autosomal-recessive disorder causing intractable seizures in neonates and infants. This case report describes an infant with pyridoxine-dependent seizures with microcephaly and discusses a probable pathogenetic mechanism of microcephaly in this condition.
Tan
Hüseyin
H
Department of Child Neurology, Yakutiye Research Hospital, Atatürk University, Faculty of Medicine, Erzurum, Turkey.
Kardaş
Fatih
F
Büyükavci
Mustafa
M
Karakelleoğlu
Cahit
C
D006801:Humans; D007223:Infant; D008297:Male; D008831:Microcephaly / Q000150:complications / Q000188:drug therapy / Q000209:etiology*; D011736:Pyridoxine / Q000008:administration & dosage / Q000627:therapeutic use*; D012640:Seizures / Q000150:complications / Q000188:drug therapy / Q000209:etiology*
D011736:Pyridoxine