title: [Vertebral body replacement with expandable titanium cages].
abstract: OBJECTIVE
  The aim of vertebral body replacement is the stabilisation and restoration of the anterior column of the spine with removal of the diseased region. We present our results of stabilisation, pain reduction and neurological improvement using vertebral-body replacement systems
  
  
  METHODS
  Between April 1997 and December 2002, 53 patients with malignant vertebral destruction or instability due to traumatic and osteoporotic fracture were treated. We evaluated the results after vertebrectomy and vertebral body replacement by using expandable titanium cages in a retrospective study.
  
  
  RESULTS
  The average follow-up time was 18.9 +/- 19.9 months. The mean operation time was 173.2 +/- 77.4 minutes. Intraoperatively, we saw no implant-related complications. Perioperatively, complications appeared in 18 patients (34.0 %). 4 of them were severe, with 2 patients dying. In the total follow-up, 16 patients died, 10 of them (62.5 %) due to tumour progression. Pain reduction was reported in 52.7 %, neurological improvement in 48.0 %. One patient had a loosening of his posterior instrumentation in the further follow-up due to tumour growth with dislocation of the cage and a deterioration of his neurological deficit.
  
  
  CONCLUSIONS
  By using vertebral body replacement systems, sufficient stabilisation of the vertebral column, pain reduction and neurological improvement can be achieved with an acceptable perioperative risk.
authors.affiliation: Orthopädische Abteilung des Rehabilitationskrankenhauses Ulm, Orthopädische Klinik, Ulm. benjamin.ulmar@rku.de
authors.forename: B
authors.initials: B
authors.lastname: Ulmar
authors.forename: B
authors.initials: B
authors.lastname: Cakir
authors.forename: K
authors.initials: K
authors.lastname: Huch
authors.forename: W
authors.initials: W
authors.lastname: Puhl
authors.forename: M
authors.initials: M
authors.lastname: Richter
mesh_terms: D001860:Bone Plates; D005260:Female; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D007593:Joint Instability / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D016103:Spinal Fractures / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D013123:Spinal Fusion / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D014025:Titanium; D016896:Treatment Outcome
chemical_list: D014025:Titanium