title: Effect of renal artery stenting on renal function in patients with ischemic nephropathy.
abstract: The aim of this study was to evaluate the effects of stenting on blood pressure and renal functions in azotemic patients with proximal/ostial atherosclerotic renal artery stenosis. Thirteen azotemic patients (5 females, 8 males, average age, 62.7 +/- 8.3 years) who had renal artery stenosis were included in the study. Their blood pressure, estimated glomerular filtration rate (EGFR), and creatinine levels were measured at baseline and during follow-up. Stents were implanted successfully in all of the cases. The average stent diameter and stent length were 7.2 +/- 0.5 mm and 17.2 +/- 3.4 mm, respectively. Antihypertensive drug was abandoned in 1 (7.6%) patient, reduced in 10 patients (76.9%), and not changed in 2 (15.3%) patients. Significant improvement was observed in the mean serum creatinine level at the 12th month when compared with baseline (2.56 +/- 0.88; 1.83 +/- 0.62, P < 0.001). EGFR was 18.38 +/- 4.64 before the procedure and 22.67 +/- 3.81 during follow-up (P < 0.0001). According to the GFR criteria, renal function was determined to be worse in 1 (7.6%) patient, stabilized in 2 (15.3%), and improved in 10 (76.9%) patients. One patient died during the follow-up period. Angiographic restenosis was observed in 2 (15.3%) patients. Follow-up major events were observed in 3 (23%) patients. Stenting azotemic patients with renal artery stenosis is a reliable and effective procedure for achieving an improvement in renal function.
authors.affiliation: Department of Cardiology, Flrat University, Elazig, Turkey.
authors.forename: Erdogan
authors.initials: E
authors.lastname: Ilkay
authors.forename: Ihsan A
authors.initials: IA
authors.lastname: Günal
authors.forename: Mustafa
authors.initials: M
authors.lastname: Yavuzkir
authors.forename: Necati
authors.initials: N
authors.lastname: Dağli
authors.forename: Ilgin
authors.initials: I
authors.lastname: Karaca
authors.forename: Huseyin
authors.initials: H
authors.lastname: Celiker
authors.forename: Ayhan
authors.initials: A
authors.lastname: Doğukan
authors.forename: Nadi
authors.initials: N
authors.lastname: Arslan
mesh_terms: D000368:Aged; D001161:Arteriosclerosis / Q000150:complications*; D001794:Blood Pressure; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D003404:Creatinine / Q000097:blood; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007511:Ischemia / Q000209:etiology / Q000628:therapy*; D007668:Kidney / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D012078:Renal Artery Obstruction / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D015607:Stents; D016896:Treatment Outcome; D014511:Uremia / Q000209:etiology / Q000628:therapy
chemical_list: D003404:Creatinine