Dynamic analysis of multivariate failure time data.
We present an approach for analyzing internal dependencies in counting processes. This covers the case with repeated events on each of a number of individuals, and more generally, the situation where several processes are observed for each individual. We define dynamic covariates, i.e., covariates depending on the past of the processes. The statistical analysis is performed mainly by the nonparametric additive approach. This yields a method for analyzing multivariate survival data, which is an alternative to the frailty approach. We present cumulative regression plots, statistical tests, residual plots, and a hat matrix plot for studying outliers. A program in R and S-PLUS for analyzing survival data with the additive regression model is available on the web site http://www.med.uio.no/imb/stat/addreg. The program has been developed to fit the counting process framework.
Aalen
Odd O
OO
Section of Medical Statistics, University of Oslo, Blindern, N-0317 Oslo, Norway. o.o.aalen@basalmed.uio.no
Fosen
Johan
J
Weedon-Fekjaer
Harald
H
Borgan
Ornulf
O
Husebye
Einar
E
D001699:Biometry / Q000379:methods*; D003627:Data Interpretation, Statistical; D005769:Gastrointestinal Motility; D006801:Humans; D015233:Models, Statistical; D015999:Multivariate Analysis; D012044:Regression Analysis; D012890:Sleep / Q000502:physiology; D016019:Survival Analysis