title: Defective repair replication of DNA in xeroderma pigmentosum. 1968.
abstract: Most forms of the human hereditary disease xeroderma pigmentation (XP) are due to a defect in nucleotide excision repair of DNA damage in skin cells associated with exposure to sunlight. This discovery by James Cleaver had an important impact on our understanding of nucleotide excision repair in mammals.
authors.affiliation: Laboratory of Radiobiology, University of California Medical Center, San Francisco, California, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Cleaver
mesh_terms: D004260:DNA Repair; D004261:DNA Replication; D004273:DNA, Neoplasm / Q000528:radiation effects; D005823:Genetics / Q000266:history; D049673:History, 20th Century; D006801:Humans; D012878:Skin Neoplasms / Q000235:genetics / Q000266:history*; D013472:Sunlight / Q000009:adverse effects; D014983:Xeroderma Pigmentosum / Q000235:genetics / Q000266:history*
chemical_list: D004273:DNA, Neoplasm