Allergy symptom response to intradermal testing-based immunotherapy: a retrospective study of clinical practice.
OBJECTIVE
Evaluate the multiple end-organ targets affected by intradermal testing (IDT)-based immunotherapy. Study design and setting We conducted a retrospective medical record review of 139 patients, as well as a follow-up questionnaire in a university setting.


RESULTS
Statistically significant differences (t-tests, P < 0.05) were observed in the prevalence of symptoms after IDT-based immunotherapy for each category (ear, eye, nasal, and throat). When divided into treatment time groups, the reduction was less in the first group (0-6 months therapy), than the subsequent groups (6-24 months and >24 months). The reduction leveled off after 6 months of therapy, with no difference seen between the 6- to 24-month and >24-month groups.


CONCLUSIONS
IDT-based immunotherapy has a broad response on otolaryngic allergy symptoms that appears to be consistent over time.


CONCLUSIONS
IDT-based immunotherapy is an effective form of treatment for allergy-induced diseases of the head and neck.
Rouse
David
D
Department of Otolaryngology Head and Neck Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA. drouse@kumc.edu
Park
Debra L
DL
Sanford
Thomas
T
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy*; D007167:Immunotherapy; D008297:Male; D008875:Middle Aged; D010038:Otorhinolaryngologic Diseases / Q000276:immunology* / Q000628:therapy*; D012189:Retrospective Studies; D012882:Skin Tests; D011795:Surveys and Questionnaires