title: Sclerotherapy for congenital lesions in the head and neck.
abstract: OBJECTIVE
  This study retrospectively reviews the results of sclerotherapy using several sclerosants for congenital lesions of the head and neck.
  
  
  METHODS
  Between May 1990 and May 2002, patients with lymphatic malformations were treated by sclerotherapy; 10 with bleomycin, and 25 with OK-432. OK-432 sclerotherapy was also applied in 9 patients with plunging ranula and in 1 patient with branchial anomaly. Percutaneous sclerotherapy with ethanolamine oleate was used in 29 patients with venous malformations, and 28 patients with pyriform sinus fistula were treated by trichloroacetic acid chemocauterization.
  
  
  RESULTS
  Overall, two thirds of patients with these lesions showed marked to complete response. One case of mortality occurred in the bleomycin sclerotherapy group. However, no major complications by other sclerosants were found. In lymphatic malformations, history of excision before sclerotherapy was a poor prognostic factor.
  
  
  CONCLUSIONS
  Sclerotherapy using these sclerosants is a safe and effective primary treatment for congenital lesions in the head and neck.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Cancer Research Institute, Seoul, Korea. kimkwang@plaza.snu.ac.kr
authors.forename: Kwang Hyun
authors.initials: KH
authors.lastname: Kim
authors.forename: Myung-Whun
authors.initials: MW
authors.lastname: Sung
authors.forename: Jong-Lyel
authors.initials: JL
authors.lastname: Roh
authors.forename: Moon Hee
authors.initials: MH
authors.lastname: Han
mesh_terms: D000293:Adolescent; D000328:Adult; D001761:Bleomycin / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D006257:Head; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008206:Lymphatic Diseases / Q000151:congenital* / Q000628:therapy*; D008208:Lymphatic System / Q000002:abnormalities*; D008297:Male; D009333:Neck; D010844:Picibanil / Q000627:therapeutic use; D012189:Retrospective Studies; D015911:Sclerotherapy
chemical_list: D001761:Bleomycin; D010844:Picibanil