title: [Preoperative betablockers use in vascular and thoracic surgery].
abstract: OBJECTIVE
  The aim of this study was to evaluate betablockers use and effect in the preoperative period in vascular and thoracic surgery.
  
  
  METHODS
  Retrospective study concerning patients scheduled for high or intermediate surgical risk procedure (n = 321) in a French vascular and thoracic surgery department during 2002. Eligibility for betablocker therapy was defined as previously described for inclusion criteria in Mangano's Study (N Engl J Med 1996;335:1713-20). Therapy effect was evaluated with heart rate in the operating room.
  
  
  RESULTS
  Forty-six percent (99/213) of eligible patients for betablockers were really treated in the preoperative period. In patients treated with betablockers, 40% appeared in the operating room with the most favorable heart rate (55-65 b/min). During surgical procedure, heart rate over 80 b/min was observed in more than 30% of patients with betablocker therapy. In patients eligible for betablocker therapy but untreated with these drugs, only 12% have received betablockers in the preoperative period.
  
  
  CONCLUSIONS
  Betablockers underuse is important in the preoperative period, and effect on heart rate is rarely optimal. This fact should encourage physicians to apply protocols for perioperative betablockers administration.
authors.affiliation: Service d'anesthésie-réanimation chirurgicale, assistance publique-hôpitaux de Paris, centre hospitalier universitaire Beaujon, 100, avenue du Général-Leclerc, 92110 Clichy, France.
authors.forename: T
authors.initials: T
authors.lastname: Geeraerts
authors.forename: P
authors.initials: P
authors.lastname: Albaladejo
authors.forename: H
authors.initials: H
authors.lastname: Beloeil
authors.forename: A
authors.initials: A
authors.lastname: Wernet
authors.forename: R
authors.initials: R
authors.lastname: Bocquet
authors.forename: Y
authors.initials: Y
authors.lastname: Castier
authors.forename: J
authors.initials: J
authors.lastname: Marty
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000368:Aged; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D011183:Postoperative Complications / Q000453:epidemiology / Q000503:physiopathology; D011300:Preoperative Care; D012189:Retrospective Studies; D012307:Risk Factors; D019616:Thoracic Surgical Procedures; D014656:Vascular Surgical Procedures
chemical_list: D000319:Adrenergic beta-Antagonists