Role of the urinary calcium in the growth of calcium stone.
We analyzed the relationship between the rate and clinical factors. The growth rate per year of the stone was measured by Nabeshima's method in 29 male patients with renal calcium stones including 7 pure calcium oxalate (CaOx) stones and 22 mixed calcium oxalate and calcium phosphate (CaOx-CaP) stones. The 24-hour urinary excretion of calcium, phosphate, uric acid and magnesium were assayed under an ambulatory free diet in 5 patients with CaOx stones and 15 with CaOx-CaP stones. The relationship between the growth rate and the urinary excretion of stone-forming parameters was examined. We found a significant positive correlation between the growth rate of calcium stones and the urinary excretion of calcium (p<0.02). In addition, the growth rate of CaOx-CaP stone was significantly higher than that of pure CaOx stone (p<0.05). In conclusion, urinary calcium is important for the growth of renal calcium stones.
Murayama
Tetsuo
T
Department of Urology, Sagamihara National Hospital.
Sakai
Naoki
N
Takano
Tetsuzou
T
Yamada
Tetsuo
T
D000328:Adult; D000368:Aged; D002118:Calcium / Q000652:urine; D002129:Calcium Oxalate / Q000652:urine*; D002130:Calcium Phosphates / Q000652:urine*; D006801:Humans; D008274:Magnesium / Q000652:urine; D008297:Male; D008875:Middle Aged; D014527:Uric Acid / Q000652:urine; D014545:Urinary Calculi / Q000737:chemistry* / Q000378:metabolism
D002130:Calcium Phosphates; D002129:Calcium Oxalate; D014527:Uric Acid; C020243:calcium phosphate; D008274:Magnesium; D002118:Calcium