title: Antimicrobial activity and cytotoxicity of Cirsium tenoreanum.
abstract: The methanol and ethyl acetate extracts of the aerial parts of Cirsium tenoreanum, have been evaluated for their phytochemical constituents and antibacterial and cytotoxic properties. Three flavonoids, apigenin, quercetin-3-O-galactoside and kaempferol-3-O-ramnoside, were isolated. The ethyl acetate extract showed a good antiproliferative activity.
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università della Calabria, 87036 Rende (CS), Italy. mr.loizzo@unical.it
authors.forename: Monica Rosa
authors.initials: MR
authors.lastname: Loizzo
authors.forename: Giancarlo A
authors.initials: GA
authors.lastname: Statti
authors.forename: Rosa
authors.initials: R
authors.lastname: Tundis
authors.forename: Filomena
authors.initials: F
authors.lastname: Conforti
authors.forename: Sebastiano
authors.initials: S
authors.lastname: Andò
authors.forename: Francesco
authors.initials: F
authors.lastname: Menichini
mesh_terms: D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D045744:Cell Line, Tumor / Q000187:drug effects; D031180:Cirsium; D004926:Escherichia coli / Q000187:drug effects; D005419:Flavonoids / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D000972:Antineoplastic Agents, Phytogenic; D005419:Flavonoids; D010936:Plant Extracts