title: [Clinical application of intro-aortic balloon pump and centrifugal pump in low cardiac output syndrome after coronary artery bypass grafting].
abstract: OBJECTIVE
  To explore the clinical application of Intra-aortic balloon pump (IABP) and centrifugal pump in low cardiac output syndrome (LCOS) after coronary artery bypass grafting (CABG).
  
  
  METHODS
  From April 2000 to January 2004, 5 patients suffered serious LCOS after CABG in our department. Because maximum vasoactive agent had no significant effect, we supported these 5 patients with IABP and centrifugal pumps. The centrifugal pumps were connected with cannulas of right superior pulmonary vein and ascending aorta. The flow rate of the centrifugal pumps were increased to 3-4 L/min gradually. The dosage of vasoactive agent and flow rate of the centrifugal pumps were decreased gradually after hemodynamics stabilized.
  
  
  RESULTS
  All 5 patients' hemodynamics were improved significantly after the left ventricular assist by IABP and centrifugal pumps. Five patients were weaned from the centrifugal pumps after 4 to 7 days successfully. But some degree damage to blood cells and renal function were detected. Renal function of 3 patients were recovered gradually after centrifugal pumps removed and discharged successfully, One patient died of acute renal failure, 1 patient died of multiple organ failure, 5 patients need transfusion of whole blood or concentrated erythrocytes and 4 patients need transfusion of platelets.
  
  
  CONCLUSIONS
  There were significant improvements in hemodynamics after support with IABP and centrifugal pumps in the patients who suffered serious LCOS with less effect of maximum vasoactive agent after CABG. Some complications on blood cells and renal function should be paid more attention.
authors.affiliation: Department of Cardiac Surgery, First Hospital of Peking University, Beijing 100034, China.
authors.forename: Xi-hui
authors.initials: XH
authors.lastname: Li
authors.forename: Feng
authors.initials: F
authors.lastname: Xiao
authors.forename: Hu-jun
authors.initials: HJ
authors.lastname: Cui
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Feng-jie
authors.initials: FJ
authors.lastname: Li
authors.forename: Nai-qing
authors.initials: NQ
authors.lastname: Song
authors.forename: Ying-li
authors.initials: YL
authors.lastname: Du
authors.forename: Ming-li
authors.initials: ML
authors.lastname: Zhang
mesh_terms: D000368:Aged; D002303:Cardiac Output, Low / Q000209:etiology / Q000601:surgery*; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D006353:Heart-Assist Devices; D006801:Humans; D007423:Intra-Aortic Balloon Pumping; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome