Computer simulation analysis of blood alcohol.
A mathematical model using an iterative algorithm based on the Widmark formula is used to simulate a continuous spectrum of the expected blood alcohol concentration from start of alcohol dosage to time of specific event in numerical and graphic form. Absorption is based on flexible first order rates with provision for an optional good-fit model of the delaying effect of food. Elimination is based initially on selectable zero order rates followed by first order kinetics at low blood alcohol concentrations. A correlation coefficient of 0.94 was obtained in comparisons of projected to observed blood alcohol concentrations. A measurement of the area under the curve is provided. The software program utilizing the algorithm is suitable for forensic and clinical applications.
Rockerbie
D W
DW
Department of Economics, University of Lethbridge, Lethbridge, Canada.
Rockerbie
R A
RA