title: Three-dimensional first trimester fetal volumetry: comparison with crown rump length.
abstract: BACKGROUND
  Ultrasonographic volumetry measurements of human fetus have become possible using three-dimensional ultrasound systems.
  
  
  OBJECTIVE
  To evaluate the weekly increase of fetal volume during the first trimester of normal pregnancies compared to the crown rump length and creating a first trimester fetal volume nomogram.
  
  
  METHODS
  Crown rump length and three-dimensional ultrasonographic volumetry measurements performed on 72 first trimester fetuses using virtual organ computer aided analysis (VOCAL).
  
  
  RESULTS
  A significant direct correlation (r = 0.939) was found between the calculated fetal volumes and crown rump lengths. A 6-12 weeks gestation fetal volume nomogram was proposed.
  
  
  CONCLUSIONS
  Fetal volume database in the first trimester may serve as a reference table for diagnosis of early pregnancy failure.
authors.affiliation: Ultrasound Unit, Deparment of Obstetrics and Gynecology, Sapir Medical Center, Kfar Saba 44281, Israel. Bensonm@clalit.org.il
authors.forename: R
authors.initials: R
authors.lastname: Aviram
authors.forename: D Kamar
authors.initials: DK
authors.lastname: Shpan
authors.forename: O
authors.initials: O
authors.lastname: Markovitch
authors.forename: A
authors.initials: A
authors.lastname: Fishman
authors.forename: R
authors.initials: R
authors.lastname: Tepper
mesh_terms: D000886:Anthropometry / Q000379:methods*; D018568:Crown-Rump Length; D005260:Female; D047109:Fetal Development / Q000502:physiology*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D049451:Nomograms; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D016216:Ultrasonography, Prenatal