title: [The inhibitive effect of IgY toothpaste against oral Streptococcus mutans].
abstract: OBJECTIVE
  To study the effect of the toothpaste containing IgY against oral Streptococcus mutans.
  
  
  METHODS
  140 subjects were divided into 2 groups randomly (test group and control group). Before the beginning of the test, every subject underwent a elution period in order to lessen the other interference factors, then used different toothpastes were used respectively and the test began. Streptococcus mutans values were determined with Dentocult SM Strip just before test, at 1, 3, 7, 30 days after toothpaste used and 14 days after stopping toothpaste used.
  
  
  RESULTS
  (1) In test group,Streptococcus mutans values decreased at 1 day after toothpaste used. In control group Streptococcus mutans values decreased at 3 days after toothpaste used. (2) Streptococcus mutans values decreased gradually in each groups after toothpaste used. (3) In test group, 2 weeks after stopping toothpaste used, Streptococcus mutans values were still suppressed.
  
  
  CONCLUSIONS
  The application of the toothpaste containing IgY may reduce oral Streptococcus mutans levels significantly.
authors.affiliation: Department of Preventive & Pediatric Dentistry, Ninth People's Hospital, School of Stomatology, Shanghai Second Medical University. Shanghai 200011, China.
authors.forename: Zheng-Bing
authors.initials: ZB
authors.lastname: Chi
authors.forename: Yan-Xia
authors.initials: YX
authors.lastname: Gao
authors.forename: Ying
authors.initials: Y
authors.lastname: Pan
authors.forename: Bin
authors.initials: B
authors.lastname: Zhang
authors.forename: Xi-Pin
authors.initials: XP
authors.lastname: Feng
mesh_terms: D002648:Child; D003731:Dental Caries / Q000517:prevention & control; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000008:administration & dosage*; D007155:Immunologic Factors / Q000008:administration & dosage*; D008297:Male; D013295:Streptococcus mutans / Q000187:drug effects*; D014100:Toothpastes / Q000008:administration & dosage*
chemical_list: C016512:IgY; D007136:Immunoglobulins; D007155:Immunologic Factors; D014100:Toothpastes