title: Paroxysmal cold haemoglobinuria as a tardive complication of idiopathic myelofibrosis.
abstract: Paroxysmal cold haemoglobinuria (PCH) is an autoimmune haemolytic anaemia caused by the Donath-Landsteiner antibody. It is classically described in association with chronic syphilis or after acute viral infections. We describe the first case of PCH presented as a late manifestation of advanced myelofibrosis associated with antiphospholipid syndrome, that promptly responded to high dosage of prednisone.
authors.affiliation: Department of Cellular Biotechnology and Hematology, University La Sapienza, Rome, Italy. breccia@bce.uniroma1.it
authors.forename: Massimo
authors.initials: M
authors.lastname: Breccia
authors.forename: Gianna Maria
authors.initials: GM
authors.lastname: D'Elia
authors.forename: Gabriella
authors.initials: G
authors.lastname: Girelli
authors.forename: Stefania
authors.initials: S
authors.lastname: Vaglio
authors.forename: Fabiana
authors.initials: F
authors.lastname: Gentilini
authors.forename: Sarlo
authors.initials: S
authors.lastname: Chiara
authors.forename: Giuliana
authors.initials: G
authors.lastname: Alimena
mesh_terms: D000368:Aged; D005260:Female; D006457:Hemoglobinuria, Paroxysmal / Q000209:etiology*; D006801:Humans; D055728:Primary Myelofibrosis / Q000209:etiology*