title: Application of semiconductors for dosimetry of fast-neutron therapy beam.
abstract: Two types of ion implanted miniature p-i-n diodes were tested in a d(48.5) + Be fast-neutron beam produced in the Detroit superconducting cyclotron. The increase in forward voltage drop caused by neutron-induced damage was correlated with neutron dose measured in a water phantom. The neutron and gamma dose components were predetermined using twin detector (Tissue-equivalent ion chamber paired with miniature Geiger-Müller counter) method. The increase in the voltage drop for 1 mA injection current was monitored together with the cyclotron beam target current, thus the differential voltage drop could be defined precisely for given radiation dose. The average neutron sensitivities of tested diodes were 1.284 +/- 0.014 and 0.528 +/- 0.058 mV per cGy. The miniature detectors can be utilised in characterisation of small radiation fields and in the regions of high dose gradient as well as for in vivo dosimetry of the patients undergoing fast-neutron therapy.
authors.affiliation: Karmanos Cancer Institute, Wayne State University, 3990 John R. Street, Detroit, MI 48201, USA. myudelev@dmc.org
authors.forename: M
authors.initials: M
authors.lastname: Yudelev
authors.forename: K
authors.initials: K
authors.lastname: Alyousef
authors.forename: J
authors.initials: J
authors.lastname: Brandon
authors.forename: V
authors.initials: V
authors.lastname: Perevertailo
authors.forename: M L F
authors.initials: ML
authors.lastname: Lerch
authors.forename: A B
authors.initials: AB
authors.lastname: Rosenfeld
mesh_terms: D004867:Equipment Design; D019544:Equipment Failure Analysis; D005214:Fast Neutrons / Q000627:therapeutic use*; D006801:Humans; D017247:Neutron Capture Therapy / Q000295:instrumentation* / Q000379:methods; D011835:Radiation Protection / Q000295:instrumentation*; D011874:Radiometry / Q000295:instrumentation* / Q000379:methods; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation* / Q000379:methods; D015203:Reproducibility of Results; D018570:Risk Assessment / Q000379:methods; D012666:Semiconductors; D012680:Sensitivity and Specificity; D014159:Transducers