Unique asymmetric catalysis of cis-beta metal complexes of salen and its related Schiff-base ligands.
Complexes of chiral salen and its related tetradentate Schiff-base ligands adopt three different configurations, trans, cis-alpha and cis-beta. Of these complexes, trans-complexes have been widely used as catalysts for various asymmetric reactions. However, recent studies have disclosed that cis-beta metallosalen and its related complexes show unique asymmetric catalyses that cannot be achieved by trans-metallosalen complexes. The present article summarizes generation of cis-beta metallosalen and its related complexes, their structural features, and their application to asymmetric syntheses.
Katsuki
Tsutomu
T
Department of Chemistry, Faculty of Science, Graduate School, Kyushu University Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan. katsuscc@mbox.nc.kyushu-u.ac.jp