title: SABmark--a benchmark for sequence alignment that covers the entire known fold space.
abstract: The Sequence Alignment Benchmark (SABmark) provides sets of multiple alignment problems derived from the SCOP classification. These sets, Twilight Zone and Superfamilies, both cover the entire known fold space using sequences with very low to low, and low to intermediate similarity, respectively. In addition, each set has an alternate version in which unalignable but apparently similar sequences are added to each problem.
authors.affiliation: Department of Ultrastructure, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussel, Belgium. ivwalle@vub.ac.be
authors.forename: Ivo
authors.initials: I
authors.lastname: Van Walle
authors.forename: Ignace
authors.initials: I
authors.lastname: Lasters
authors.forename: Lode
authors.initials: L
authors.lastname: Wyns
mesh_terms: D000465:Algorithms; D000595:Amino Acid Sequence; D019985:Benchmarking / Q000379:methods*; D008969:Molecular Sequence Data; D017510:Protein Folding; D011506:Proteins / Q000032:analysis / Q000737:chemistry* / Q000145:classification*; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods*; D017386:Sequence Homology, Amino Acid; D012984:Software
chemical_list: D011506:Proteins