High incidence of type 2 diabetes in peroxisome proliferator-activated receptor gamma2 Pro12Ala carriers exposed to a high chronic intake of trans fatty acids and saturated fatty acids.
Pisabarro
Raul Eduardo
RE
Department of Endocrinology and Metabolism, University of the Republic, Montevideo, Uruguay.
Sanguinetti
Carlos
C
Stoll
Mario
M
Prendez
Daniel
D
D000328:Adult; D000409:Alanine; D019943:Amino Acid Substitution; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology* / Q000235:genetics*; D004041:Dietary Fats; D002149:Energy Intake; D005260:Female; D006580:Genetic Carrier Screening; D006801:Humans; D008297:Male; D008875:Middle Aged; D047495:PPAR gamma / Q000235:genetics*; D010865:Pilot Projects; D017354:Point Mutation; D020641:Polymorphism, Single Nucleotide; D011392:Proline; D012307:Risk Factors; D044242:Trans Fatty Acids; D014583:Uruguay
D004041:Dietary Fats; D047495:PPAR gamma; D044242:Trans Fatty Acids; D011392:Proline; D000409:Alanine