title: Estrogen-induced severe acute pancreatitis in a male.
abstract: BACKGROUND
  Acute pancreatitis is related to drugs in 1.4-2% of cases. Estrogens are an uncommon but well-known risk factor of pancreatitis in women and men with pre-existing hyperlipidemia.
  
  
  METHODS
  We report the case of a 37-year-old man with covert hypertriglyceridemia who developed a severe life-threatening pancreatitis strongly associated with estrogen therapy preparatory to sex change surgery, characterized by a massive triglyceride level, pancreatic insufficiency and multiple organ failure at the time of the diagnosis. Other causes of the disease were ruled out.
  
  
  CONCLUSIONS
  To our knowledge, this is the first description of severe necrotizing estrogen-induced pancreatitis in a male. Baseline abnormal triglyceride levels should be checked by physicians before starting estrogen therapy in women and men.
authors.affiliation: Department of Surgery, San Gerardo Hospital, University of Milano-Bicocca, Monza, MI, Italy.
authors.forename: Elisa
authors.initials: E
authors.lastname: Perego
authors.forename: Alberto
authors.initials: A
authors.lastname: Scaini
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Romano
authors.forename: Claudio
authors.initials: C
authors.lastname: Franciosi
authors.forename: Franco
authors.initials: F
authors.lastname: Uggeri
mesh_terms: D000208:Acute Disease; D000328:Adult; D004967:Estrogens / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010195:Pancreatitis / Q000139:chemically induced*
chemical_list: D004967:Estrogens