Cdk5 deregulation in the pathogenesis of Alzheimer's disease.
Cruz
Jonathan C
JC
Department of Pathology, Howard Hughes Medical Institute, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA. jonathan_cruz@hms.harvard.edu
Tsai
Li-Huei
LH
D000544:Alzheimer Disease / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D016564:Amyloid beta-Protein Precursor / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000473:pathology; D051360:Cyclin-Dependent Kinase 5; D018844:Cyclin-Dependent Kinases / Q000378:metabolism*; D006801:Humans; D009419:Nerve Tissue Proteins / Q000378:metabolism / Q000633:toxicity; D013379:Substrate Specificity
D016564:Amyloid beta-Protein Precursor; D009419:Nerve Tissue Proteins; C089495:neuronal Cdk5 activator (p25-p35); D051360:Cyclin-Dependent Kinase 5; C495905:CDK5 protein, human; D018844:Cyclin-Dependent Kinases