RNA editing in hepatitis delta virus: unsolved puzzles.
RNA editing, or post-transcriptional changes in the sequences of RNAs, is being increasingly recognized as an important player in the regulation of gene expression in vertebrates and invertebrates. Different types of RNA editing have been reported. This review discuss the type of RNA editing caused by cellular enzymes known as adenosine deaminases that act on RNAs (ADARs), and it"s significance in the lifecycle of an RNA virus, hepatitis delta virus.
Jayan
Geetha C
GC
Division of Viral Products, CBER, FDA, Bethesda, MD 20892, USA. gjayan@softhome.net
D000818:Animals; D003698:Hepatitis Delta Virus / Q000235:genetics*; D006801:Humans; D017393:RNA Editing / Q000235:genetics*; D012367:RNA, Viral / Q000235:genetics
D012367:RNA, Viral