[A case of liver metastasis of colon cancer responding remarkably to 5'-DFUR].
A 65-year-old man was referred to our hospital because of diarrhea due to sigmoid colon cancer. Abdominal CT scan revealed a hepatic tumor (S8) about 2 cm in diameter. We performed a sigmoidectomy and planned to resect the liver metastasis 1 or 2 months later. Pathological findings showed moderately differentiated adenocarcinoma, s, n1. Two weeks after the surgery, 5'-DFUR was administered at 600 mg/day. An abdominal CT scan 2 months later demonstrated regression of the liver metastasis and another scan 4 months later showed the tumor had disappeared. 5'-DFUR was administered for about 2 years. Five years after the surgery, the patient is alive without recurrence and CEA level is in normal range.
Nakazaki
Takayuki
T
Dept of Surgery, Japanese Red Cross Nagasaki Genbaku Hospital.
Shibata
Kenichiro
K
Haseba
Masatoshi
M
Taniguchi
Hideki
H
Nakao
Susumu
S
Takahara
Osamu
O
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D012809:Colon, Sigmoid / Q000601:surgery; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005467:Floxuridine / Q000627:therapeutic use*; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D012074:Remission Induction; D012811:Sigmoid Neoplasms / Q000473:pathology* / Q000601:surgery
D000964:Antimetabolites, Antineoplastic; D005467:Floxuridine; C025034:doxifluridine