title: Regioselective enzymatic acetylation of the aglycone moiety of a secoiridoid glucoside. Two new secoiridoid glucoside acetates.
abstract: Candida antarctica lipase (CAL) catalyses the regioselective acetylation of the 10-hydroxyl group of 10-hydroxyoleoside dimethyl ester, a secoiridoid glucoside, using THF as a solvent and ethyl acetate or vinyl acetate as acetyl group suppliers. Two acetyl derivatives at 3'- and 6'-sites of the glucosidic ring of 10-acetoxyoleoside dimethylester, not previously described, were obtained by acetylation in the same conditions.
authors.affiliation: Instituto Universitario de Bioorgánica, Universidad de La Laguna, Carretera de la Esperanza, Tenerife, Canary Islands, Spain. japerez@ull.es
authors.forename: José Andrés
authors.initials: JA
authors.lastname: Pérez
authors.forename: Carlos
authors.initials: C
authors.lastname: Boluda
authors.forename: Hermelo
authors.initials: H
authors.lastname: López
authors.forename: Juan Manvel
authors.initials: JM
authors.lastname: Trujillo
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Hernández
mesh_terms: D000107:Acetylation; D004800:Enzymes, Immobilized / Q000737:chemistry; D039823:Iridoids / Q000138:chemical synthesis*; D031660:Jasminum / Q000737:chemistry; D008049:Lipase; D015394:Molecular Structure
chemical_list: D004800:Enzymes, Immobilized; D039823:Iridoids; D008049:Lipase