[Gastroduodenal bleedings in critical illness].
Acute erosive lesions of upper parts of gastrointestinal tract with bleeding aggravate severe burn trauma, postoperative period after extensive surgeries and is the often component of polyorganic insufficiency syndrome. Gastric secretion in patients with severe burn trauma and neurotrauma was studied. Decrease of gastric secretory function due to central paresis of gastrointestinal tract and reflux of bile into stomach was seen in majority of patients with neurotrauma and acute gastric ulcers. On the contrary, in patients with burn shock increase of acid-secretory function of stomach was revealed. Schemes of prophylaxis and treatment of acute ulcers were developed. They included antacid therapy (for patients with increased secretion), regulators of motor-evacuatory function of stomach and intestine (for patients with paresis), drugs increased regenerative properties of mucosa, early enteral nutrition with balanced mixtures. This treatment in combination with hemostatic therapy and cure of main disease permitted to reduce number of gastroduodenal bleedings and lethality in these patients.
Ermolov
A S
AS
Tveritneva
L F
LF
Pakhomova
G V
GV
Tsarenko
S V
SV
Kudriashova
N E
NE
Sordia
D G
DG
Spiridonova
T G
TG
D002056:Burns / Q000150:complications; D006259:Craniocerebral Trauma / Q000150:complications; D016638:Critical Illness; D005744:Gastric Acid / Q000378:metabolism; D006471:Gastrointestinal Hemorrhage / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology / Q000503:physiopathology; D010437:Peptic Ulcer / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D010438:Peptic Ulcer Hemorrhage / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control