title: Frequency of catamenial seizure exacerbation in women with localization-related epilepsy.
abstract: This investigation assessed the frequency of catamenial epilepsy in 87 women who charted seizures and menses during three cycles. Catamenial epilepsy designation was made if two of three cycles showed at least one of three previously defined catamenial patterns. Among ovulatory cycles, average daily seizure frequency was significantly greater during the perimenstrual and preovulatory phases. Among anovulatory cycles, average daily seizure frequency was substantially less during the midfollicular phase than during the remainder of the cycle. Overall, 39.1% of the women had catamenial epilepsy.
authors.affiliation: Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215.
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Herzog
authors.forename: Cynthia L
authors.initials: CL
authors.lastname: Harden
authors.forename: Joyce
authors.initials: J
authors.lastname: Liporace
authors.forename: Page
authors.initials: P
authors.lastname: Pennell
authors.forename: Donald L
authors.initials: DL
authors.lastname: Schomer
authors.forename: Michael
authors.initials: M
authors.lastname: Sperling
authors.forename: Kristen
authors.initials: K
authors.lastname: Fowler
authors.forename: Blagovast
authors.initials: B
authors.lastname: Nikolov
authors.forename: Sevie
authors.initials: S
authors.lastname: Shuman
authors.forename: Melanee
authors.initials: M
authors.lastname: Newman
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D000927:Anticonvulsants / Q000627:therapeutic use; D004828:Epilepsies, Partial / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008597:Menstrual Cycle / Q000502:physiology*; D008875:Middle Aged; D011446:Prospective Studies; D012640:Seizures / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*
chemical_list: D000927:Anticonvulsants