title: Improvement of sensitivity in the determination of organochlorine pesticides using a PSS injector with GC-ECD.
abstract: This paper describes the optimisation of a PSS injector in a gas chromatograph with a programmed pneumatic control (PPC) for the determination of 21 organochlorine pesticides. The injection of high volumes of sample (20 microl) improves the detection limits and allows a reduction in the amount of sample processed. The injection conditions were selected by a Plackett-Burman design followed by a central composite design. The LODs obtained in the optimum conditions were compared with those obtained with splitless/ECD. Finally, the method was successfully applied to the analysis of a leachate and vegetable samples.
authors.affiliation: Department of Analytical Chemistry, University of A Coruña, Campus da Zapateira, 15071 A Coruña, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Concha-Graña
authors.forename: M I
authors.initials: MI
authors.lastname: Turnes-Carou
authors.forename: S
authors.initials: S
authors.lastname: Muniategui-Lorenzo
authors.forename: P
authors.initials: P
authors.lastname: López-Mahía
authors.forename: E
authors.initials: E
authors.lastname: Fernández-Fernández
authors.forename: D
authors.initials: D
authors.lastname: Prada-Rodríguez
mesh_terms: D002849:Chromatography, Gas / Q000295:instrumentation / Q000379:methods; D006843:Hydrocarbons, Chlorinated / Q000032:analysis*; D010575:Pesticides / Q000032:analysis*; D012680:Sensitivity and Specificity; D013997:Time Factors
chemical_list: D006843:Hydrocarbons, Chlorinated; D010575:Pesticides