title: GC-FID/MS method for the impurity profiling of synthetic d-allethrin.
abstract: A GC/FID/MS method was developed for the identification and quantification of d-allethrin (DA) and its major impurities in commercial samples. Optimisation of the experimental conditions was carried out considering such important requirements as resolution, reproducibility, detection limits of 0.1% (m/m) for the impurities, and short analysis time. Under the optimised final conditions the method was validated for specificity, precision (CV% = 0.133 at 2.10 mg/mL and CV% = 0.035 at 3.00 mg/mL), linearity (0-3.00 microg injected), limits of detection (0.09 ng injected) and quantitation (0.28 ng injected), and robustness. The DA related impurities were identified by using a GC/MS method with ion trap mass detection and also by comparison with synthesised standards. The most abundant impurities were crysolactone, allethrolone, chrysanthemic acid, and chloro-derivatives of DA.
authors.affiliation: 'Endura SpA, V.le Pietramellara 5, 40100 Bologna, Italy.
authors.forename: Matteo
authors.initials: M
authors.lastname: Bragieri
authors.forename: Alessandra
authors.initials: A
authors.lastname: Liverani
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Zanotti
authors.forename: Valerio
authors.initials: V
authors.lastname: Borzatta
authors.forename: Jessica
authors.initials: J
authors.lastname: Fiori
authors.forename: Vanni
authors.initials: V
authors.lastname: Cavrini
authors.forename: Vincenza
authors.initials: V
authors.lastname: Andrisano