[Characteristics and therapeutic strategies of nosocomial pneumonia in postoperative patients with acute hypertensive intracerebral hemorrhage].
OBJECTIVE
To investigate the characteristics of postoperative nosocomial pneumonia in patients with acute hypertensive intracerebral hemorrhage after evacuation of hematoma and the strategies of prevention and treatment.


METHODS
Retrospective analysis was performed on the clinical data of surgically treated patients with acute hypertensive intracerebral hemorrhage in the Department of Neurosurgery from 2000 to 2003. The patients were divided into a group who developed nosocomial pneumonia to compare with a group who did not. Sputum was cultured B and drug sensitivity of isolated bacteria was performed. Appropriate treatment measures were given according to clinical manifestations.


RESULTS
In 112 post operative patients with acute hypertensive intracerebral hemorrhage, nosocomial pneumonia developed in 29 patients (25.89%), and 65.99% of microorganisms isolated from respiratory secretion was Gram-negative bacteria. The predominant bacteria were Pseudomonas aeruginosa and Staphylococcus aureus. The mortality was 34.48% (10/29 cases). The prognosis of patients with nosocomial pneumonia was worse than the controls (7.23%, 6/83 cases, P<0.01).


CONCLUSIONS
The preventive and therapeutic strategies for nosocomial pneumonia in postoperative patients with acute hypertensive intracerebral hemorrhage include reduction of risk-factors, surveillance of pathogens, rational use of antibiotics, respiratory and nutrition support, and so on.
Tong
Ying
Y
Department of Neurosurgery, First Affiliated Hospital, Medical College, Zhejiang University, Hangzhou 310003, Zhejiang, China.
Zhan
Ren-ya
RY
Su
Qun
Q
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003428:Cross Infection / Q000382:microbiology / Q000628:therapy*; D005260:Female; D006801:Humans; D020299:Intracranial Hemorrhage, Hypertensive / Q000150:complications / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000382:microbiology / Q000628:therapy*; D011183:Postoperative Complications / Q000382:microbiology / Q000628:therapy; D012189:Retrospective Studies