title: New approaches to replacing failing organs.
abstract: The foremost cause of death and disability is organ failure. Failure of the heart, lungs, kidney, and liver is typically addressed by organ transplantation; however, the number of human organs available for this purpose is quite limited. For this reason, some new technologies are being advanced for the treatment of organ failure. This communication summarizes potential limitations of these technologies.
authors.affiliation: Transplantation Biology, Mayo Clinic, Rochester, Minnesota 55905, USA.
authors.forename: M
authors.initials: M
authors.lastname: Cascalho
authors.forename: B M
authors.initials: BM
authors.lastname: Ogle
authors.forename: J L
authors.initials: JL
authors.lastname: Platt
mesh_terms: D006801:Humans; D012086:Reoperation; D033581:Stem Cell Transplantation / Q000009:adverse effects / Q000639:trends; D014180:Transplantation / Q000639:trends*; D017211:Treatment Failure