DD1.5k, the gene preferentially expressed in bloodstream isolates of vancomycin-resistant Enterococcus faecium.
Vancomycin-resistant Enterococcus faecium (VREFM) is becoming a threatening pathogen. We identified a gene called DD1.5K by differential display-PCR, which was preferentially expressed in the bloodstream isolates of VREFM. Due to its amino acid similarity to transfer complex protein, trsE, and tissue-specific expression, this gene may be involved in virulence of VREFM.
Kim
Seung-Han
SH
Clinical Research Institute, The Catholic University of Korea, Seoul, 150-713, Korea.
Lee
Dong-Gun
DG
Yoo
Jin-Hong
JH
Choi
Su-Mi
SM
Choi
Jung-Hyun
JH
Shin
Wan-Shik
WS
Lee
Kyungwon
K
Yong
Dongeun
D
Lee
Wee Gyo
WG
Youn
Byung-S
BS
Kang
Moon-Won
MW
D000222:Adaptation, Physiological; D000595:Amino Acid Sequence; D000818:Animals; D001426:Bacterial Proteins / Q000096:biosynthesis / Q000235:genetics*; D001769:Blood / Q000382:microbiology*; D002645:Chickens / Q000097:blood / Q000382:microbiology; D004269:DNA, Bacterial / Q000737:chemistry / Q000302:isolation & purification; D016984:Enterococcus faecium / Q000235:genetics* / Q000254:growth & development / Q000302:isolation & purification / Q000378:metabolism; D020869:Gene Expression Profiling / Q000379:methods; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology; D006801:Humans; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D020713:Vancomycin Resistance / Q000235:genetics; D037521:Virulence Factors / Q000235:genetics*
D001426:Bacterial Proteins; D004269:DNA, Bacterial; D037521:Virulence Factors