[Inhibition of Longzhi extracts on tumor growth of transplanted H22 and S180 in mice].
OBJECTIVE
To study the inhibitory effect of Longzhi extracts (extracts from a Chinese herbal compound) on the growth of transplanted hepatoma H22 and sarcoma S180 in mice.


METHODS
Certain dosage of Longzhi extracts was dissolved into distilled water to obtain the suspension of definite concentration. The suspension of 0.2 ml was planted on the right forefoot of each mouse. The mice were randomly divided into groups 24 hours later and treated for 7 days. One day after the treatment stopped, the mice were sacrificed and the tumor masses were taken out and weighed.


RESULTS
The inhibition rates of Longzhi extracts on the tumor of transplanted H22 and S180 were 63% and 41% respectively.


CONCLUSIONS
Longzhi extracts has antitumor action.
Peng
Hai-Yan
HY
Department of Internal Medicine of Traditional Chinese Medicine, First Clinical College of Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu Province 210029, China. penghaiyanwan@xinhuanet.com
Zhang
Yong-Hong
YH
Wang
Meng
M
Xia
Dong
D
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy* / Q000473:pathology; D049109:Cell Proliferation / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008114:Liver Neoplasms, Experimental / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D051379:Mice; D009368:Neoplasm Transplantation; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use; D016896:Treatment Outcome
D004365:Drugs, Chinese Herbal; D010936:Plant Extracts