title: The synthesis of unsymmetrically N-substituted chiral 1,4,7-triazacyclononanes.
abstract: A number of chiral unsymmetrically N-substituted 1,4,7-triazacyclononane ligands have been prepared by modular methods. The key step in the synthesis centres on the macrocyclisation of three tertiary amide precursors under standard Richman-Atkins conditions which allows for subsequent N-functionalisation.
authors.affiliation: Department of Chemistry, Queen Mary, University of London, Mile End Road, London, UK E1 4NS.
authors.forename: J Erik W
authors.initials: JE
authors.lastname: Scheuermann
authors.forename: Kevin F
authors.initials: KF
authors.lastname: Sibbons
authors.forename: David M
authors.initials: DM
authors.lastname: Benoit
authors.forename: Majid
authors.initials: M
authors.lastname: Motevalli
authors.forename: Michael
authors.initials: M
authors.lastname: Watkinson
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D008024:Ligands; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D006571:Heterocyclic Compounds; D008024:Ligands; C075712:1,4,7-triazacyclononane