title: Unexpected formation of tetrasubstituted 2,3-dihydrofurans from the reactions of beta-keto polyfluoroalkanesulfones with aldehydes.
abstract: Catalyzed by piperidine, the reactions of beta-keto polyfluoroalkanesulfones with aromatic aldehydes afforded the unexpected tetrasubstituted 2,3-dihydrofurans in good yields, probably proceeding through the normal Knoevenagel condensation products. This reaction provided an efficient and novel method for the stereoselective synthesis of fluorine-containing tetrasubstituted trans-2,3-dihydrofurans.
authors.affiliation: Key Laboratory of Organofluorine Chemistry, Shanghai Institution of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin lu, Shanghai 200032, PR China.
authors.forename: Chunhui
authors.initials: C
authors.lastname: Xing
authors.forename: Shizheng
authors.initials: S
authors.lastname: Zhu