title: Antivirals against DNA viruses (hepatitis B and the herpes viruses).
abstract: Antiviral drugs against DNA viruses are widely used for the management of diseases caused by infections with the Herpes viruses and have recently been introduced for Hepatitis B. There are also several emerging treatments (i.e. those that are in clinical development) and novel treatments that are still in the preclinical phase. Although the majority of emerging drugs are nucleoside analogues, there is a trend towards the development of non-nucleosidic drugs with unique mechanisms of action, in the hope that efficacy will be maximised and drug resistance and viral rebound minimised.
authors.affiliation: hbsc, Krutscheider Weg 96, 42327 Wuppertal, Germany.
authors.forename: Guy
authors.initials: G
authors.lastname: Hewlett
authors.forename: Sabine
authors.initials: S
authors.lastname: Hallenberger
authors.forename: Helga
authors.initials: H
authors.lastname: Rübsamen-Waigmann
mesh_terms: D000998:Antiviral Agents / Q000737:chemistry / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003586:Cytomegalovirus Infections / Q000188:drug therapy; D006509:Hepatitis B / Q000188:drug therapy*; D006561:Herpes Simplex / Q000188:drug therapy; D006562:Herpes Zoster / Q000188:drug therapy; D006566:Herpesviridae Infections / Q000188:drug therapy*; D006801:Humans
chemical_list: D000998:Antiviral Agents