Fenretinide activates a distinct apoptotic pathway.
Dmitrovsky
Ethan
E
D000970:Antineoplastic Agents / Q000494:pharmacology*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017209:Apoptosis / Q000187:drug effects*; D001092:Arachidonate 12-Lipoxygenase / Q000378:metabolism; D045744:Cell Line, Tumor; D002518:Ceramides / Q000378:metabolism; D004790:Enzyme Induction / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology; D017313:Fenretinide / Q000494:pharmacology*; D005732:Gangliosides / Q000378:metabolism; D005964:Glucosyltransferases / Q000378:metabolism; D006801:Humans; D009447:Neuroblastoma / Q000188:drug therapy* / Q000378:metabolism; D010088:Oxidoreductases / Q000378:metabolism; D034741:RNA, Small Interfering / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000378:metabolism*; D013108:Sphingomyelin Phosphodiesterase / Q000378:metabolism
D000970:Antineoplastic Agents; D002518:Ceramides; D004791:Enzyme Inhibitors; D005732:Gangliosides; D034741:RNA, Small Interfering; D017382:Reactive Oxygen Species; D017313:Fenretinide; D010088:Oxidoreductases; D001092:Arachidonate 12-Lipoxygenase; C108138:dihydroceramide desaturase; D005964:Glucosyltransferases; C023246:ceramide glucosyltransferase; D013108:Sphingomyelin Phosphodiesterase