Myasthenic crisis following cisplatin chemotherapy in a patient with malignant thymoma.
Malignant thymomas are associated with numerous autoimmune disorders including myasthenia gravis. Myastenia gravis is characterized by antibodies against the acetylcholine receptors located on the neuromuscular junction of the skeletal muscle. We present a case with malignant thymoma who developed myasthenia crisis while he was treated with cisplatin chemotherapy.
Solak
Y
Y
Dept of Internal Medicine, Hacettepe University, Faculty of Medicine, Ankara, Turkey.
Dikbas
O
O
Altundag
K
K
Guler
N
N
Ozisik
Y
Y
D000970:Antineoplastic Agents / Q000009:adverse effects*; D002675:Child, Preschool; D002945:Cisplatin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal / Q000187:drug effects; D009157:Myasthenia Gravis / Q000139:chemically induced* / Q000473:pathology; D009469:Neuromuscular Junction / Q000276:immunology* / Q000503:physiopathology; D011950:Receptors, Cholinergic / Q000276:immunology / Q000378:metabolism; D013945:Thymoma / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D013953:Thymus Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000276:immunology
D000970:Antineoplastic Agents; D011950:Receptors, Cholinergic; D002945:Cisplatin