title: Invasive superficial spreading melanomas arising from clinically normal skin.
abstract: We provide documentation of the onset of 3 invasive superficial spreading melanomas arising from clinically normal skin and correlation with histologic lack of nevus association. Clinical, dermoscopic, and pathologic features of these "de novo" melanomas, which became invasive while small in diameter and had few clinical criteria for diagnosis, are reported.
authors.affiliation: Department of Dermatology, University of North Carolina at Chapel Hill, NC 27599, USA. nthomas@med.unc.edu
authors.forename: Nancy E
authors.initials: NE
authors.lastname: Thomas
authors.forename: Pamela
authors.initials: P
authors.lastname: Groben
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008545:Melanoma / Q000175:diagnosis / Q000473:pathology*; D009361:Neoplasm Invasiveness; D016609:Neoplasms, Second Primary / Q000473:pathology; D009508:Nevus, Pigmented / Q000473:pathology; D010781:Photography; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology*