Proteolytic cleavage of von Willebrand factor by ADAMTS-13 prevents uninvited clumping of blood platelets.
Furlan
Miha
M
Central Hematology Laboratory, University Hospital/Inselspital, Bern, Switzerland. furlan@swissonline.ch
D051722:ADAM Proteins; D000071120:ADAMTS13 Protein; D000818:Animals; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008666:Metalloendopeptidases / Q000172:deficiency / Q000266:history* / Q000502:physiology; D008954:Models, Biological; D010974:Platelet Aggregation / Q000502:physiology*; D011697:Purpura, Thrombotic Thrombocytopenic / Q000097:blood / Q000266:history; D013557:Switzerland; D014841:von Willebrand Factor / Q000266:history* / Q000502:physiology
D014841:von Willebrand Factor; D051722:ADAM Proteins; D008666:Metalloendopeptidases; D000071120:ADAMTS13 Protein; C099604:ADAMTS13 protein, human