Additional observations on the sporozoite transmission of Plasmodium knowlesi to monkeys.
Saimiri boliviensis monkeys were infected by the intravenous injection of 50 sporozoites of the H strain of Plasmodium knowlesi dissected from the salivary glands of Anopheles dirus mosquitoes; prepatent periods were 11, 12, 13, 13, 13, and 16 days. Sporozoites of P. knowlesi stored frozen for 7 days, 53 days, 20 mo, 7 yr and 7 mo, and 11 yr and 5 mo induced infections in Macaca mulatta monkeys with prepatent periods of 7, 6, 8, 10, and 7 days, respectively. After frozen storage for 11 yr and 5 mo, infections were induced in S. boliviensis with prepatent periods of 10-13 days.
Collins
William E
WE
Division of Parasitic Diseases and Animal Resources Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA. wec1@cdc.gov
Sullivan
JoAnn S
JS
Nace
Douglas
D
Williams
Tyrone
T
Williams
Allison
A
Galland
G Gale
GG
Barnwell
John W
JW
D000818:Animals; D000852:Anopheles / Q000469:parasitology; D015925:Cryopreservation / Q000662:veterinary; D007303:Insect Vectors / Q000469:parasitology; D008253:Macaca mulatta / Q000469:parasitology*; D008288:Malaria / Q000469:parasitology / Q000635:transmission / Q000662:veterinary*; D008992:Monkey Diseases / Q000469:parasitology / Q000635:transmission*; D016790:Plasmodium knowlesi / Q000472:pathogenicity*; D012453:Saimiri / Q000469:parasitology*