[Effect of reducing caloric intake on mice transplanted with S180 ascitic cancer].
OBJECTIVE
To examine the effect of different reduced caloric intake on mice transplanted with S180 ascitic tumor.


METHODS
The institute for cancer research (ICR) mice were randomly divided into control group, 3.0 standard feed (SF) group, 2.0 SF group and 1.3 SF group. The mice in control group were fed enough (about 5 g/d) dietary intake, while the amounts of dietary intake in the latter three groups were scaled down in the proportion of 65%, which were 3.0 g, 2.0 g and 1.3 g standard feed respectively. Meanwhile the essential vitamins were added to the latter three groups to keep the amount of intake the same as that of the control's.


RESULTS
For most of the mice, the caloric intake obviously prolonged the mean survival days and improved the life quality was 7.14 kcal/d, and the fasting blood glucose level was 2-3 mmol/L.


CONCLUSIONS
Properly reduced caloric intake and keeping lower blood glucose level is beneficial to prolonging the survival time of mice transplanted with S180 ascitic cancer.
Liu
Xian-Yong
XY
Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Hua
Wei-Guo
WG
Chu
Wei-Zhong
WZ
Jiang
Dong-Liang
DL
Chen
Hui-Ju
HJ
Wang
Yu-Ying
YY
Liu
Xue-Mei
XM
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D002149:Energy Intake; D005260:Female; D051379:Mice; D008813:Mice, Inbred ICR; D009368:Neoplasm Transplantation; D012510:Sarcoma 180 / Q000401:mortality*
D001786:Blood Glucose