title: Clustering gene expression data with temporal abstractions.
abstract: This paper describes a new technique for clustering short time series coming from gene expression data. The technique is based on the labelling of the time series through temporal trend abstractions and a consequent clustering of the series on the basis of their labels. Clustering is performed at three different levels of aggregation of the original time series, so that the results are organized and visualized as a three-levels hierarchical tree. Results on simulated and on yeast data are shown. The technique appears robust and efficient and the results obtained are easy to be interpreted.
authors.affiliation: Dipartimento di Informatica e Sistemica, Università di Pavia, Italy. lucia@aim.unipv.it
authors.forename: L
authors.initials: L
authors.lastname: Sacchi
authors.forename: R
authors.initials: R
authors.lastname: Bellazzi
authors.forename: C
authors.initials: C
authors.lastname: Larizza
authors.forename: P
authors.initials: P
authors.lastname: Magni
authors.forename: T
authors.initials: T
authors.lastname: Curk
authors.forename: U
authors.initials: U
authors.lastname: Petrovic
authors.forename: B
authors.initials: B
authors.lastname: Zupan
mesh_terms: D000465:Algorithms; D016000:Cluster Analysis; D019295:Computational Biology; D020869:Gene Expression Profiling; D020411:Oligonucleotide Array Sequence Analysis; D010363:Pattern Recognition, Automated; D013995:Time