Three-dimensional first trimester fetal volumetry: comparison with crown rump length.
BACKGROUND
Ultrasonographic volumetry measurements of human fetus have become possible using three-dimensional ultrasound systems.


OBJECTIVE
To evaluate the weekly increase of fetal volume during the first trimester of normal pregnancies compared to the crown rump length and creating a first trimester fetal volume nomogram.


METHODS
Crown rump length and three-dimensional ultrasonographic volumetry measurements performed on 72 first trimester fetuses using virtual organ computer aided analysis (VOCAL).


RESULTS
A significant direct correlation (r = 0.939) was found between the calculated fetal volumes and crown rump lengths. A 6-12 weeks gestation fetal volume nomogram was proposed.


CONCLUSIONS
Fetal volume database in the first trimester may serve as a reference table for diagnosis of early pregnancy failure.
Aviram
R
R
Ultrasound Unit, Deparment of Obstetrics and Gynecology, Sapir Medical Center, Kfar Saba 44281, Israel. Bensonm@clalit.org.il
Shpan
D Kamar
DK
Markovitch
O
O
Fishman
A
A
Tepper
R
R
D000886:Anthropometry / Q000379:methods*; D018568:Crown-Rump Length; D005260:Female; D047109:Fetal Development / Q000502:physiology*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D049451:Nomograms; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D016216:Ultrasonography, Prenatal