title: [The role of stretching the sinus node artery in initiation of atrial fibrillation].
abstract: In anaesthetised dogs with open chest (n = 10), against the background of the Gd3+ (a blocking agent of mechano-sensitive ion channels), acetylcholine perfusion induced no significant changes either in probability of atrial fibrillation occurrence or in the paroxysm duration. The Gd3+ did not alter the deceleration of the sinus rhythm either. Therefore the mechanism of spontaneous occurrence of atrial cholinergic fibrillation seems not to be associated with the trigger activity induced by an increased blood pressure in the right atrium.
authors.forename: A V
authors.initials: AV
authors.lastname: Glukhov
authors.forename: V V
authors.initials: VV
authors.lastname: Fedorov
authors.forename: O P
authors.initials: OP
authors.lastname: Trifonova
authors.forename: G G
authors.initials: GG
authors.lastname: Beloshapko
authors.forename: A V
authors.initials: AV
authors.lastname: Iushmanova
authors.forename: L V
authors.initials: LV
authors.lastname: Rozennshtraukh
mesh_terms: D000109:Acetylcholine / Q000008:administration & dosage; D000818:Animals; D001281:Atrial Fibrillation / Q000523:psychology*; D016280:Atrial Function, Right / Q000187:drug effects / Q000502:physiology*; D004285:Dogs; D005682:Gadolinium / Q000008:administration & dosage; D007473:Ion Channels / Q000037:antagonists & inhibitors / Q000502:physiology; D012849:Sinoatrial Node / Q000502:physiology*; D014665:Vasodilator Agents / Q000008:administration & dosage
chemical_list: D007473:Ion Channels; D014665:Vasodilator Agents; D005682:Gadolinium; D000109:Acetylcholine