title: Biochemical analysis of neoplastic versus nonneoplastic abdominal effusions in dogs.
abstract: This prospective study of 15 dogs evaluated biochemical parameters in abdominal effusions of neoplastic and nonneoplastic origin in an attempt to identify markers for malignant effusions. Dogs in the neoplastic group had statistically significant lower glucose concentrations (mean, 72.6 mg/dL versus 110.0 mg/dL; P=0.0431) and higher lactate levels (mean, 3.81 mmol/L versus 1.68 mmol/L; P=0.0377) in their abdominal fluid than did dogs in the nonneoplastic group, indicating that low glucose and high lactate in abdominal effusions may be markers for neoplasia.
authors.affiliation: Veterinary Teaching Hospital, University of Illinois, Urbana, Illinois 61801, USA.
authors.forename: Derek D
authors.initials: DD
authors.lastname: Nestor
authors.forename: Sheila M
authors.initials: SM
authors.lastname: McCullough
authors.forename: David J
authors.initials: DJ
authors.lastname: Schaeffer
mesh_terms: D034841:Abdominal Cavity / Q000473:pathology*; D000818:Animals; D001202:Ascitic Fluid / Q000737:chemistry*; D014408:Biomarkers, Tumor / Q000032:analysis*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D005947:Glucose / Q000032:analysis; D019344:Lactic Acid / Q000032:analysis; D009369:Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D011446:Prospective Studies; D012680:Sensitivity and Specificity
chemical_list: D014408:Biomarkers, Tumor; D019344:Lactic Acid; D005947:Glucose