title: [Therapeutic approach in locally advanced and complicated rectosigmoid and genital cancers].
abstract: Locally advanced and complicated rectosigmoidian and genital cancers raise many therapeutic problems for surgeons. The most frequently used therapeutic methods nowadays are: radiotherapy, chemotherapy, surgical procedures, immunotherapy and other modern methods that aren't in the current clinical use yet. In a trial of 456 patients with locally advanced and complicated rectosigmoidian cancers and 632 patients with genital cancers we performed 573 (52.6%) radical surgical procedures and 515 (47.4%) palliative procedures, 301 (27.6%) of these being permanent colostomy (257 terminal and 44 in continuity). All of the patients received radiotherapy or chemotherapy pre and/or after surgery. The survival was between 5-7 months in the trial of patients with permanent colostomy, between 12-36 months in the trial of patients with palliative surgical procedures and adjuvant treatment and between 5-17 years in the trial of patients with radical surgical procedures and neo- and adjuvant therapy.
authors.affiliation: Clinica Chirurgicală Colţea, Bucureşti.
authors.forename: N
authors.initials: N
authors.lastname: Angelescu
authors.forename: E
authors.initials: E
authors.lastname: Popa
authors.forename: M
authors.initials: M
authors.lastname: Angelescu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005833:Genital Neoplasms, Female / Q000150:complications / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy / Q000379:methods; D009367:Neoplasm Staging; D012004:Rectal Neoplasms / Q000150:complications / Q000473:pathology / Q000628:therapy*; D012189:Retrospective Studies; D012383:Romania / Q000453:epidemiology; D012811:Sigmoid Neoplasms / Q000150:complications / Q000473:pathology / Q000628:therapy*; D016019:Survival Analysis; D016896:Treatment Outcome