Nanoparticle systems for the targeted release of active principles of proteic nature.
The preparation and characterization of nanoparticles based on biodegradable/bioerodible polymers is reported. They have been designed for the controlled-targeted release of proteic drugs such as alpha-interferon and for the release of active principles in tissue engineering. The amenability of some of the prepared polymeric matrices to be used in the fabrication of micro and nano patterned scaffolds is also described.
Solaro
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R
Department of Chemistry and Industrial Chemistry, University of Pisa, via Risorgimento 35, 56126 Pisa, Italy. rosola@dcci.unipi.it
Chiellini
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F
Signori
F
F
Fiumi
C
C
Bizzarri
R
R
Chiellini
E
E