title: Duodenogastric reflux eradicates Helicobacter pylori after distal gastrectomy.
abstract: OBJECTIVE
  Patients who undergo distal gastrectomy often develop duodenogastric reflux and preoperative H. pylori infection is eradicated spontaneously after distal gastrectomy in some patients. However, whether a causal relationship exists has not yet been studied. This report examines the correlation between H. pylori eradication and the amount of duodenogastric reflux following distal gastrectomy.
  
  
  METHODS
  Among 72 consecutive patients who underwent curative distal gastrectomy with radical lymphadenectomy for gastric cancer, 37 patients had H. pylori infection preoperatively and were included in this study. The period of bile reflux (percent time) into the gastric remnant was measured with the Bilitec 2000 under standardized conditions on the 14th day after the surgery. Endoscopic examination was performed to determine the presence of H. pylori infection on week 12 after surgery.
  
  
  RESULTS
  The percent time was higher in patients whose H. pylori infection had been eradicated after distal gastrectomy (58.1+/-9.2%) than in patients who had H. pylori infection after distal gastrectomy (33.8+/-5.7%).
  
  
  CONCLUSIONS
  Duodenogastric reflux correlates with spontaneous eradication of H. pylori infection following distal gastrectomy.
authors.affiliation: Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine Osaka, Japan. fuku@eva.hi-ho.ne.jp
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Fukuhara
authors.forename: Harushi
authors.initials: H
authors.lastname: Osugi
authors.forename: Nobuyasu
authors.initials: N
authors.lastname: Takada
authors.forename: Masashi
authors.initials: M
authors.lastname: Takemura
authors.forename: Shiegru
authors.initials: S
authors.lastname: Lee
authors.forename: Shinichi
authors.initials: S
authors.lastname: Taguchi
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kaneko
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Yushi
authors.initials: Y
authors.lastname: Fujiwara
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nishizawa
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kinoshita
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001655:Bile Reflux / Q000473:pathology*; D004383:Duodenogastric Reflux / Q000473:pathology*; D005260:Female; D005743:Gastrectomy; D005753:Gastric Mucosa / Q000473:pathology; D018530:Gastric Stump / Q000473:pathology*; D005756:Gastritis / Q000473:pathology; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000473:pathology / Q000601:surgery*; D016480:Helicobacter pylori; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000473:pathology*; D011379:Prognosis; D012075:Remission, Spontaneous; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*