[A comparative study of the antioxidant activity of salbutamol hemisuccinate and essentiale in rats with experimental phetoplacental insufficiency].
The experiments on rats with phetoplacental insufficiency induced by tetrachloromethane showed that beta2-mimetic salbutamol hemisuccinate (salgim) exhibits antioxidant activity. The effect was most pronounced in placenta, where salgim exceeded in activity the well-known reference drug essentiale.
Zaĭchenko
A V
AV
D000420:Albuterol / Q000494:pharmacology*; D000818:Animals; D000975:Antioxidants / Q000378:metabolism / Q000494:pharmacology*; D002374:Catalase / Q000378:metabolism; D005260:Female; D005979:Glutathione Peroxidase / Q000378:metabolism; D005980:Glutathione Reductase / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects; D008315:Malondialdehyde / Q000378:metabolism; D010713:Phosphatidylcholines / Q000494:pharmacology*; D010920:Placenta / Q000378:metabolism; D010927:Placental Insufficiency / Q000378:metabolism*; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar; D013482:Superoxide Dismutase / Q000378:metabolism; D014599:Uterus / Q000378:metabolism
D000975:Antioxidants; D010713:Phosphatidylcholines; C011246:essential 303 forte; D008315:Malondialdehyde; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D005980:Glutathione Reductase; D005982:Glutathione Transferase; D000420:Albuterol