Perinatal outcome of pregnancies complicated by placenta accreta.
OBJECTIVE
The purpose of the study was to characterize the perinatal outcome of pregnancies complicated by placenta accreta.


METHODS
We conducted a case-control analysis of all deliveries between the years 1990 and 2000 that were complicated by placenta accreta. Perinatal variables included in the analysis were gestational age at delivery, birth weight, Apgar scores, and perinatal mortality. Statistical analysis was performed using both the unpaired and paired approach. P <.05 was considered significant.


RESULTS
The study encompassed 34,450 deliveries, from which 310 cases of placenta accreta were diagnosed (0.9%) and compared with 310 matched controls. In the pregnancies complicated by placenta accreta, we found a statistically significant increase in preterm deliveries (10.7% versus 1%, P <.001, odds ratio 12.1, 95% confidence interval 3.7-39.9) and small-for-gestational-age babies (27.3% versus 14%, P <.001, odds ratio 5.05, 95% confidence interval 1.46-3.28).


CONCLUSIONS
Pregnancies complicated by placenta accreta are at increased risk for perinatal adverse outcome. We speculate that these findings may arise from pathological implantation of the placenta, resulting in interference with normal fetal growth.
Gielchinsky
Yuval
Y
Department of Obstetrics and Gynecology, Hadassah Medical Center, The Hebrew University, Jerusalem, Israel. yuvalgi@attglobal.net
Mankuta
David
D
Rojansky
Nathan
N
Laufer
Neri
N
Gielchinsky
Ilan
I
Ezra
Yossef
Y
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D010921:Placenta Accreta; D011247:Pregnancy; D011256:Pregnancy Outcome