title: Titanium catalysis in the Ugi reaction of alpha-amino acids with aromatic aldehydes.
abstract: [reaction: see text] Ugi reaction between an (S)-alpha-amino acid, an aromatic aldehyde, and an isonitrile proceeds best under catalysis by TiCl(4) in MeOH. The sense of diastereoinduction is (S,S).
authors.affiliation: Laboratoire de Synthèse et Méthodologie Organiques, CNRS UMR 5181, and Centre Commun de Diffractométrie, Université Claude Bernard Lyon 1 and Ecole Supérieure de Chimie, Physique et Electronique de Lyon, 69622 Villeurbanne, France.
authors.forename: Thomas
authors.initials: T
authors.lastname: Godet
authors.forename: Yannick
authors.initials: Y
authors.lastname: Bonvin
authors.forename: Guillaume
authors.initials: G
authors.lastname: Vincent
authors.forename: Daphné
authors.initials: D
authors.lastname: Merle
authors.forename: Alain
authors.initials: A
authors.lastname: Thozet
authors.forename: Marco A
authors.initials: MA
authors.lastname: Ciufolini
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000596:Amino Acids / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D017672:Nitrogen Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D014025:Titanium / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D000596:Amino Acids; D017672:Nitrogen Compounds; D014025:Titanium