[Experience in a suburban hospital with premature termination of pregnancy in the second trimester].
The present study was performed between 1992 and 1998 and had the aim of examining the activity and side-effects of intravenously administered sulprostone for the induction of abortion in the second trimester. 160 patients were admitted to hospital. 3 were submitted to a hysterectomy; 3 underwent an abortion after cervical priming with Prostin E2 Gel (0.25 mg/ml), 154 were repeatedly treated with an infusion of sulprostone for 6 hours (500 microg Nalodor, 3 A/1000 ml 0.9% NaCl, 250 microg/h (equivalent to 4.17 microg or ca. 55 drops per min.). The mean interval for induction of abortion was 16 h 56 min; 53% of the abortions occurred within 12h; 95% of the abortions occurred within 48 h. Two inductions were unsuccessful. 12 women suffered from atonic bleeding. This study demonstrated that sulprostone infusions are suitable for the induction of abortions in the second trimester and that side-effects are rare. Particular attention must be paid to the complication of bleeding.
Kunz
J
J
Frauenklinik, Spital Zollikerberg.
D000025:Abortion, Eugenic; D000028:Abortion, Induced; D000293:Adolescent; D000328:Adult; D004107:Dilatation and Curettage; D005260:Female; D006781:Hospitals, Satellite; D006801:Humans; D007044:Hysterectomy; D007431:Intraoperative Complications / Q000601:surgery; D008875:Middle Aged; D010921:Placenta Accreta / Q000601:surgery; D018457:Placenta, Retained / Q000601:surgery; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D013557:Switzerland; D014592:Uterine Hemorrhage / Q000601:surgery