Metabolite profiling: from diagnostics to systems biology.
The concept of metabolite profiling has been around for several decades, but only recent technical innovations have allowed metabolite profiling to be carried out on a large scale - with respect to both the number of metabolites measured and the number of experiments carried out. As a result, the power of metabolite profiling as a technology platform for diagnostics, and the research areas of gene-function analysis and systems biology, is now beginning to be fully realized.
Fernie
Alisdair R
AR
Department of Molecular Physiology, Max-Planck-Institute for Molecular Plant Physiology, Am Mühlenberg 1, 14476 Golm, Germany. fernie@mpimp-golm.mpg.de
Trethewey
Richard N
RN
Krotzky
Arno J
AJ
Willmitzer
Lothar
L
D002468:Cell Physiological Phenomena; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods; D008660:Metabolism; D025202:Molecular Diagnostic Techniques; D011506:Proteins / Q000737:chemistry / Q000378:metabolism; D040901:Proteomics / Q000379:methods
D011506:Proteins