title: Metabolite profiling: from diagnostics to systems biology.
abstract: The concept of metabolite profiling has been around for several decades, but only recent technical innovations have allowed metabolite profiling to be carried out on a large scale - with respect to both the number of metabolites measured and the number of experiments carried out. As a result, the power of metabolite profiling as a technology platform for diagnostics, and the research areas of gene-function analysis and systems biology, is now beginning to be fully realized.
authors.affiliation: Department of Molecular Physiology, Max-Planck-Institute for Molecular Plant Physiology, Am Mühlenberg 1, 14476 Golm, Germany. fernie@mpimp-golm.mpg.de
authors.forename: Alisdair R
authors.initials: AR
authors.lastname: Fernie
authors.forename: Richard N
authors.initials: RN
authors.lastname: Trethewey
authors.forename: Arno J
authors.initials: AJ
authors.lastname: Krotzky
authors.forename: Lothar
authors.initials: L
authors.lastname: Willmitzer
mesh_terms: D002468:Cell Physiological Phenomena; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods; D008660:Metabolism; D025202:Molecular Diagnostic Techniques; D011506:Proteins / Q000737:chemistry / Q000378:metabolism; D040901:Proteomics / Q000379:methods
chemical_list: D011506:Proteins