title: Long-term effect of CPAP in the treatment of nocturnal stridor in multiple system atrophy.
abstract: The authors found that continuous positive airway pressure (CPAP) eliminated video-polysomnographic documented stridor in 13 multiple system atrophy (MSA) subjects with vocal cord abnormalities. Long-term follow-up showed high CPAP tolerance, no recurrence of stridor, no major side effects, subjective improvement in sleep quality, and that median survival time was similar to a group of 26 MSA patients without stridor. This study shows that in MSA, CPAP is an effective noninvasive long-term therapy for nocturnal stridor.
authors.affiliation: Neurology Service, Hospital Clínic and Instisut d'Investigació Biomèdiques August Pi i Sunyer, Barcelona, Spain. airanzo@clinic.ub.es
authors.forename: A
authors.initials: A
authors.lastname: Iranzo
authors.forename: J
authors.initials: J
authors.lastname: Santamaria
authors.forename: E
authors.initials: E
authors.lastname: Tolosa
authors.forename: I
authors.initials: I
authors.lastname: Vilaseca
authors.forename: F
authors.initials: F
authors.lastname: Valldeoriola
authors.forename: M J
authors.initials: MJ
authors.lastname: Martí
authors.forename: E
authors.initials: E
authors.lastname: Muñoz
mesh_terms: D000368:Aged; D045422:Continuous Positive Airway Pressure; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019578:Multiple System Atrophy / Q000150:complications* / Q000401:mortality; D012135:Respiratory Sounds / Q000209:etiology; D020919:Sleep Disorders, Intrinsic / Q000209:etiology / Q000628:therapy*; D016019:Survival Analysis; D016896:Treatment Outcome