title: Usefulness of the GenoType MTBC assay for differentiating species of the Mycobacterium tuberculosis complex in cultures obtained from clinical specimens.
abstract: A novel DNA strip assay, GenoType MTBC, was evaluated for differentiation of Mycobacterium tuberculosis complex species from 77 positive liquid cultures in clinical practice. Species identification (M. tuberculosis [71 strains], Mycobacterium bovis subsp. bovis [5 strains], and Mycobacterium africanum subtype I [1 strain]) results were identical to conventional results. The sensitivity was slightly higher for this test than for the AccuProbe assay.
authors.affiliation: Forschungszentrum Borstel, National Reference Center for Mycobacteria, Parkallee 18, 23845 Borstel, Germany. erichter@fz-borstel.de
authors.forename: Elvira
authors.initials: E
authors.lastname: Richter
authors.forename: Michael
authors.initials: M
authors.lastname: Weizenegger
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Fahr
authors.forename: Sabine
authors.initials: S
authors.lastname: Rüsch-Gerdes
mesh_terms: D000818:Animals; D015373:Bacterial Typing Techniques; D002417:Cattle; D015342:DNA Probes; D004269:DNA, Bacterial / Q000235:genetics; D005838:Genotype; D006801:Humans; D009163:Mycobacterium bovis / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D009169:Mycobacterium tuberculosis / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D014376:Tuberculosis / Q000382:microbiology
chemical_list: D015342:DNA Probes; D004269:DNA, Bacterial