Asymmetric transfer hydrogenation in water with a supported Noyori-Ikariya catalyst.
[reaction: see text] The poly(ethylene glycol)-supported ruthenium precatalyst shown above is highly effective for asymmetric transfer hydrogenation of unfunctionalized aromatic ketones by HCOONa in neat water, affording fast rates, good to excellent enantioselectivities, and outstanding reusability.
Li
Xiaoguang
X
Department of Chemistry, Liverpool Center for Materials and Catalysis, University of Liverpool, Liverpool L69 7ZD, UK.
Wu
Xiaofeng
X
Chen
Weiping
W
Hancock
Fred E
FE
King
Frank
F
Xiao
Jianliang
J