title: Biological and biophysical principles in extracorporal bone tissue engineering. Part III.
abstract: Over the last decade extracorporal bone tissue engineering has moved from laboratory to clinical application. The restoration of maxillofacial bones from cell harvesting through product manufacture and end-use has benefited from innovations in the fields of biomechanical engineering, product marketing and transplant research. Cell/scaffold bone substitutes face a variety of unique clinical challenges which must be addressed. This overview summarises the recent state of the art and future anticipations in the transplantation of extracorporally fabricated bone tissues.
authors.affiliation: Department of Cranio-Maxillofacial Surgery, University of Münster, Munster, Germany. ulmeyer@uni-muenster.de
authors.forename: U
authors.initials: U
authors.lastname: Meyer
authors.forename: U
authors.initials: U
authors.lastname: Joos
authors.forename: H P
authors.initials: HP
authors.lastname: Wiesmann
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D016025:Bone Transplantation / Q000379:methods; D001842:Bone and Bones / Q000166:cytology* / Q000276:immunology; D018929:Cell Culture Techniques; D006084:Graft Rejection; D006801:Humans; D010006:Osteoblasts / Q000276:immunology / Q000637:transplantation; D033581:Stem Cell Transplantation; D023822:Tissue Engineering