title: Shiga toxin-producing Escherichia coli as a possible etiological agent of chronic diarrhea.
abstract: We identified Shiga toxin-producing Escherichia coli (STEC) as the likely etiologic pathogen for chronic diarrhea in 2 patients, 1 of whom was immunocompromised with acquired immunodeficiency syndrome, and 1 of whom was immunocompetent. Both were treated with antibiotics, and neither developed systemic complications of the infection. These cases suggest that STEC infection should be considered in the differential diagnosis of chronic diarrhea.
authors.affiliation: Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA. lspacek@jhmi.edu
authors.forename: Lisa A
authors.initials: LA
authors.lastname: Spacek
authors.forename: Bryan P
authors.initials: BP
authors.lastname: Hurley
authors.forename: David W K
authors.initials: DW
authors.lastname: Acheson
authors.forename: Alexander
authors.initials: A
authors.lastname: Granok
authors.forename: Allan
authors.initials: A
authors.lastname: Currie
authors.forename: Kirk
authors.initials: K
authors.lastname: Doing
authors.forename: Cynthia L
authors.initials: CL
authors.lastname: Sears
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000209:etiology*; D004926:Escherichia coli / Q000302:isolation & purification* / Q000472:pathogenicity*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D022621:Shiga Toxin / Q000009:adverse effects* / Q000378:metabolism
chemical_list: D022621:Shiga Toxin