title: Refractory status epilepticus following self-poisoning with the organochlorine pesticide endosulfan.
abstract: We describe a case of refractory status epilepticus presenting to a rural general hospital in Sri Lanka. This patient's condition was precipitated by intentional self-poisoning with the organochlorine insecticide endosulfan. Although rarely seen in developed countries, pesticide poisoning particularly with endosulfan is an important cause of difficult-to-manage seizures in Asian countries. In this case report, we discuss the management of status epilepticus and refractory status epilepticus. Further, we specifically discuss the clinical pharmacology and toxicology of endosulfan.
authors.affiliation: Ox-Col Collaboration, Department of Clinical Medicine, University of Colombo, Colombo, Sri Lanka. dmroberts@iprimus.com.au
authors.forename: Darren M
authors.initials: DM
authors.lastname: Roberts
authors.forename: Wasantha
authors.initials: W
authors.lastname: Dissanayake
authors.forename: M H
authors.initials: MH
authors.lastname: Rezvi Sheriff
authors.forename: Michael
authors.initials: M
authors.lastname: Eddleston
mesh_terms: D000328:Adult; D004726:Endosulfan / Q000506:poisoning*; D006801:Humans; D007306:Insecticides; D008297:Male; D013226:Status Epilepticus / Q000139:chemically induced*
chemical_list: D007306:Insecticides; D004726:Endosulfan