Acute fulminant subacute sclerosing panencephalitis with absent measles and PCR studies in cerebrospinal fluid.
This report describes an atypical case of rapidly progressive subacute sclerosing panencephalitis presenting as transient visual agnosia and myoclonus in a 14-year-old male. There were no typical periodic complexes in serial electroencephalographic monitoring; cerebrospinal fluid measles antibody titer was negative. The diagnosis was made by molecular and histologic examination of open brain biopsy tissue.
Chung
Brian H Y
BH
Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, China.
Ip
Patrick P K
PP
Wong
Virginia C N
VC
Lo
Janice Y C
JY
Harding
Brian
B
D000293:Adolescent; D006801:Humans; D008297:Male; D008457:Measles / Q000134:cerebrospinal fluid* / Q000235:genetics; D016133:Polymerase Chain Reaction / Q000379:methods*; D013344:Subacute Sclerosing Panencephalitis / Q000134:cerebrospinal fluid* / Q000235:genetics