Pd(0)-catalyzed amphiphilic activation of bis-allyl alcohol and ether.
Pd(0).Et3B catalyzes amphiphilic activation of symmetric allylic diol 1 to promote electrophilic allylation at the alpha-position of aldehydes and nucleophilic allylation at the aldehyde CO, furnishing 3-methylenecyclopentalols 2 and thus generation of a zwitterionic trimethylenemethane species from the commercially available diol 1.
Mukai
Ryutaro
R
Department of Applied Chemistry, Faculty of Engineering, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Horino
Yoshikazu
Y
Tanaka
Shuji
S
Tamaru
Yoshinao
Y
Kimura
Masanari
M