title: Tracheal and central bronchial aerodynamics using virtual bronchoscopy and computational fluid dynamics.
abstract: Virtual bronchoscopy reconstructions of the airway noninvasively provide useful morphologic information of structural abnormalities such as stenoses and masses. In this paper, we show how virtual bronchoscopy can be used to perform aerodynamic calculations in anatomically realistic models. Pressure and flow patterns in a human airway were computed noninvasively. These showed decreased pressure and increased shear stress in the region of a stenosis.
authors.affiliation: School of Computational Sciences, George Mason University, Fairfax, VA 22030, USA.
authors.forename: Juan R
authors.initials: JR
authors.lastname: Cebral
authors.forename: Ronald M
authors.initials: RM
authors.lastname: Summers
mesh_terms: D000392:Air Movements; D001980:Bronchi / Q000503:physiopathology*; D001995:Bronchography; D001999:Bronchoscopy / Q000379:methods*; D003196:Computer Graphics; D003198:Computer Simulation; D003626:Data Display; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D008954:Models, Biological; D009862:Online Systems; D012123:Pulmonary Ventilation; D012212:Rheology / Q000379:methods; D014132:Trachea / Q000000981:diagnostic imaging / Q000503:physiopathology*; D014584:User-Computer Interface