title: Dynamics of some parameters of macula cariosa alba treated with fluoride gel.
abstract: OBJECTIVE
  The purpose of this study was to follow up the changes of the level of demineralization and the area of white spots during treatment with 0.42% fluoride gel.
  
  
  METHODS
  182 white spots in 27 children (aged 7 to 16) were followed. Two groups were formed - a control group (70 spots) and an experimental group (112 spots). The level of demineralization was assessed by a colour test using 2% methylene blue. Area changes were measured in square millimetres. The initial area was taken to represent 100%. Four applications at 1-week intervals were made. Changes were assessed at the end of months 1, 2, 6, and 12.
  
  
  RESULTS
  The colour test showed a decrease in the respective values during the study. The decrease was greater in the experimental group reaching statistically significant difference after the 1st month. There was a slight decrease in the average area of the spots in the control group. At the end of the study the area was reduced to 92.01% of the initial area. The average area in the experimental group at the end of the study was 28.16% of that at baseline.
  
  
  CONCLUSIONS
  These results show the high efficaciousness of the treatment of incipient caries with 0.42% fluoride gel.
authors.affiliation: Department of Pediatric Dentistry, Faculty of Dentistry, Higher Medical Institute, Plovdiv, Bulgaria.
authors.forename: M P
authors.initials: MP
authors.lastname: Kukleva
mesh_terms: D002031:Bulgaria; D002648:Child; D003731:Dental Caries / Q000503:physiopathology* / Q000517:prevention & control*; D005460:Fluorides, Topical / Q000008:administration & dosage / Q000627:therapeutic use*; D005782:Gels; D006801:Humans; D008137:Longitudinal Studies; D013997:Time Factors
chemical_list: D005460:Fluorides, Topical; D005782:Gels