title: [Recurrent thrombosis of a mitral mechanical heart valve prosthesis during puerperium--a case report].
abstract: A case of a 27-year-old female with prosthetic mitral valve is presented. Prolonged anticoagulation therapy was continued during pregnancy without complications. During puerperium, the dose of subcutaneous low molecular weight heparin was reduced due to subcutaneous blood effusions. Subsequently, the patient developed acute left ventricular heart failure due to prosthetic valve thrombosis. She underwent urgent surgery with new prosthetic valve implantation. Two weeks later she suffered another episode of acute mitral prosthetic valve thrombosis which was effectively treated with intravenous heparin. Difficulties concerning prolonged anticoagulation during pregnancy and puerperium in patients with prosthetic valves are discussed.
authors.affiliation: Klinika Kardiologii, Akademia Medyczna, Białystok, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Lisowska
authors.forename: Jolanta
authors.initials: J
authors.lastname: Prokop
authors.forename: Tomasz
authors.initials: T
authors.lastname: Hirnle
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Juszczyk
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Skibińska
authors.forename: Włodzimierz J
authors.initials: WJ
authors.lastname: Musiał
authors.forename: Ewa
authors.initials: E
authors.lastname: Klonowska-Dziatkiewicz
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage* / Q000009:adverse effects*; D006801:Humans; D008943:Mitral Valve / Q000601:surgery; D049590:Postpartum Period; D011475:Prosthesis Failure; D012008:Recurrence; D013927:Thrombosis / Q000188:drug therapy / Q000209:etiology* / Q000517:prevention & control
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight