title: A unified view of propagating and localized surface plasmon resonance biosensors.
abstract: The intense colors of noble metal nanoparticles have inspired artists and fascinated scientists for hundreds of years. In this review, we describe refractive index sensing platforms based on the tunability of the localized surface plasmon resonance (LSPR) of arrays of silver nanoparticles and of single nanoparticles. Specifically, the color associated with single nanoparticles and surface-confined nanoparticle arrays will be shown to be tunable and useful as platforms for chemical and biological sensing. Finally, the LSPR nanosensor will be compared to traditional, flat surface, propagating surface plasmon resonance sensors.
authors.affiliation: Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3113, USA.
authors.forename: Amanda J
authors.initials: AJ
authors.lastname: Haes
authors.forename: Richard P
authors.initials: RP
authors.lastname: Van Duyne
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D049329:Nanostructures / Q000737:chemistry; D012680:Sensitivity and Specificity; D020349:Surface Plasmon Resonance / Q000295:instrumentation* / Q000379:methods; D013499:Surface Properties