title: Pharmacologic management and treatment of gastroesophageal reflux disease.
abstract: Gastroesophageal reflux disease (GERD) is one of the most common diagnoses in daily practice. Diagnosis can be made on symptom evaluation, on pH-monitoring or on endoscopic findings. In contrast to commonly held opinion there is no strong evidence that lifestyle factors are a dominant factor in the pathophysiology of GERD. The various agents currently used for treatment of GERD include mucoprotective substances, antacids, H(2)-blockers and proton pump inhibitors. This article gives an overview of the pharmacological management of GERD and focuses on the differential therapy of endoscopy-negative GERD, GERD with esophagitis and maintenance therapy.
authors.affiliation: Department of Internal Medicine II - Standort Grosshadern, Ludwig-Maximilians University, Munich, Germany. martin.storr@med.uni-muenchen.de
authors.forename: M
authors.initials: M
authors.lastname: Storr
authors.forename: A
authors.initials: A
authors.lastname: Meining
mesh_terms: D005764:Gastroesophageal Reflux / Q000188:drug therapy* / Q000503:physiopathology; D005765:Gastrointestinal Agents / Q000627:therapeutic use; D017442:Histamine Agonists / Q000627:therapeutic use; D006699:Home Care Services; D006801:Humans; D054328:Proton Pump Inhibitors
chemical_list: D005765:Gastrointestinal Agents; D017442:Histamine Agonists; D054328:Proton Pump Inhibitors