Rapid and sensitive determination of morphine in street opium samples by thermal desorption gas chromatography using a microfurnace pyrolyzer.
Thermal desorption of the alkaloids in opium samples at 300 degrees C using a vertical microfurnace pyrolyzer was followed by their on-line gas chromatographic (GC) analysis on a large-bore glass capillary column. This method permitted rapid and sensitive determination of the content of the main alkaloid, morphine, in the small (ca. 100 microg) opium samples with a relative standard deviation within 4% for 5 runs. The observed morphine contents of about 12 to 15 w/w% in the given opium samples were in fairly good agreement with those estimated by a conventional GC-MS method.
Hida
Minemasa
M
Criminal Investigation Laboratory, Aichi Pref. Police HDQs, 2-1-1, Sannomaru, Nakaku, Nagoya 460-8502, Japan. DZX02003@nifty.ne.jp
Mitsui
Toshiyuki
T
Tsuge
Shin
S
Ohtani
Hajime
H
D000470:Alkaloids / Q000032:analysis; D002849:Chromatography, Gas / Q000379:methods*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D006358:Hot Temperature; D013287:Illicit Drugs / Q000032:analysis*; D009020:Morphine / Q000032:analysis*; D009892:Opium / Q000032:analysis* / Q000737:chemistry; D013696:Temperature; D013997:Time Factors
D000470:Alkaloids; D013287:Illicit Drugs; D009020:Morphine; D009892:Opium