Acrylic bone cements incorporating polymeric active components derived from salicylic acid: curing parameters and properties.
A methacrylic monomer derived from salicylic acid, 5-hydroxy-2-methacrylamido benzoic acid, 5-HMA, was incorporated with 2-hydroxyethyl methacrylate, (HEMA), in different proportions to the liquid phase of classical bone cement formulations. The monomer 5-HMA shows the ability to form molecular complexes with calcium atoms in order to improve osteointegration in the application of bone cement formulations used for the fixation of joint prostheses such as knee and hip. Kinetic parameters, peak temperature and setting time of the bone cement formulations prepared were determined, obtaining lower peak temperature values when 5-HMA was incorporated, with respect to classical acrylic bone cements based on PMMA. Mechanical and thermal properties as well as surface energy values, have been determined for all cured bone cement formulations.
Elvira
C
C
Instituto de Cy T de Polimeros, CSIC, c/ Juan de la Cierva 3, E-28006 Madrid, Spain.
Vazquez
B
B
San Román
J
J
Levenfeld
B
B
Ginebra
P
P
Gil
X
X
Planell
J A
JA