Primary leiomyosarcoma of the vagina: a case report involving a TVT allograft.
BACKGROUND
Primary malignant lesions of the vagina represent less than 2% of all gynecologic malignancies. Primary vaginal sarcomas account for about 2% of all malignant vaginal lesions, with leiomyosarcoma being the most common vaginal sarcoma found in adult women.


METHODS
We report a case of primary vaginal leiomyosarcoma occurring in the field of a prior tension-free vaginal tape (TVT) procedure using a Bard Duraderm allograft.


CONCLUSIONS
This report represents the first report, to our knowledge, of a vaginal sarcoma arising in the field of a Bard Duraderm TVT allograft. Although the product is no longer available for this use, the ongoing studies of the TVT procedure and outcomes should include this potential complication in their review.
Moller
Karen
K
Obstetrics and Gynecology, Division of Gynecologic Oncology, UNC-Chapel Hill, Chapel Hill, NC 27599, United States. kamoller@yahoo.com
Mathes
Gordon L
GL
Fowler
Wesley
W
D000368:Aged; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000209:etiology*; D013526:Surgical Mesh / Q000009:adverse effects; D014184:Transplantation, Homologous; D013519:Urogenital Surgical Procedures / Q000009:adverse effects* / Q000379:methods; D014621:Vagina / Q000601:surgery; D014625:Vaginal Neoplasms / Q000209:etiology*