XPS characterization of surface films formed on surface-modified implant materials after cell culture.
Nitrogen ion-implanted Ti-6Al-4V, Ti-5Al-2.5Fe and 316 L stainless steel and nitrogen or carbon sputter-coated samples were inoculated with rat bone marrow. The interface between the cell layer and the substrata was studied by X-ray photo-electron spectrometry and observed by scanning electron microscopy (SEM). Ca and P were detected on all materials after in vitro cell culture. Titanium appears to be present mainly in the form of TiO2.
Leitão
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INEB, Instituto de Engenharia Biomédica/FEUP, Faculdade de Engenharia da Universidade do Porto, Portugal.
Barbosa
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MA
de Groot
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