[Effect of Chinese and western medicine integration on spinning behavior of rats with Parkinson disease].
OBJECTIVE
To observe the effect of Chinese and western medicine integration on the spinning behavior of rats with Parkinson disease.


METHODS
Model of the lateral Parkinson disease was made with injection of 6-hydroxydopamine (6-OHDA) into the black substance of the right side of the brain, and the model rats were treated with madopar and Chinese herbs for nourishing the liver and kidney, clearing collaterals and detoxification. The rat's spinning behavior was observed, and was compared with the normal control group, madopar group and sham-operation group at the same time.


RESULTS
Chinese and western medicine integration could obviously reduce the spinning circles of the rats.


CONCLUSIONS
Chinese and western medicine integration can significantly improve the spinning behavior of the model rats.
He
Jian-Cheng
JC
Department of Traditional Chinese Medicine Diagnosis, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China. hejc8@yahoo.com.cn
Yuan
Can-Xing
CX
Wei
Hong-Chang
HC
Chen
Ru-Xing
RX
D000818:Animals; D008297:Male; D008516:Medicine, Chinese Traditional; D009043:Motor Activity / Q000187:drug effects; D010300:Parkinson Disease / Q000188:drug therapy* / Q000523:psychology; D051381:Rats; D017208:Rats, Wistar