Identification of sigmaB-dependent promoters using consensus-directed search of Streptomyces coelicolor genome.
SigmaB plays an important role in both osmoprotection and proper differentiation in Streptomyces coelicolor A3(2). We searched for candidate members of the sigmaB regulon from the genome database, using the consensus promoter sequence (GNNTN14-16GGGTAC/T). The list consists of 115 genes, and includes all the known sigmaB target genes and many other genes whose functions are related to stress protection and differentiation.
Lee
Eun-Jin
EJ
School of Biological Sciences and Institute of Microbiology, Seoul National University, Seoul, Korea.
Cho
You-Hee
YH
Kim
Hyo-Sub
HS
Roe
Jung-Hye
JH
D000222:Adaptation, Physiological; D001426:Bacterial Proteins / Q000378:metabolism*; D019295:Computational Biology; D016384:Consensus Sequence; D015964:Gene Expression Regulation, Bacterial; D016680:Genome, Bacterial; D009024:Morphogenesis; D009997:Osmotic Pressure; D011401:Promoter Regions, Genetic; D012808:Sigma Factor / Q000378:metabolism*; D013302:Streptomyces / Q000235:genetics*; D014158:Transcription, Genetic
D001426:Bacterial Proteins; C079011:SigB protein, Bacteria; D012808:Sigma Factor