title: [Synchronous primary lung cancers: due to the four cases].
abstract: If two primary lung cancers are present in the same time, it diagnosed as synchronous lung cancer. It constitutes 0.1-1.6% of all lung cancers. In this report, we described four cases diagnosed synchronous multiple primary lung cancers (MPLC) in between June 1999 and May 2002. Mean age was 63, and all of those were male. All patients were heavy smoker (mean 58 packet/year). Histology of lung cancers was squamous-adeno in two cases, squamous-small cell lung cancer in one case, and squamous-squamous in two cases. All patients had bilateral mass lesions and no mediastinal and systemic spread. Lesion of second primary lung cancer was unable to seen in two patient's chest X-ray. Their lesions were seen by computerized tomography in one case, and by bronchoscope only in the other case. Lesion site was left lower lobe, right lower lobe, right middle lobe, and left upper lobe (25% for each). Diagnosis of lung cancer was made by transthoracic needle biopsy in three lesion, and made by bronchoscopic biopsy in other lesions. While it is recommended that, all of MPLC lesions were staged separately and treated surgically, due to the advanced age, presence of small cell lung cancer, and inadequate post-operative respiratory reserve, surgical treatment could not apply to these patients and they received chemotherapy. Three of them was died (mean survival was 11 months). Due to the this report, we emphasized that diagnostic procedures should be done separately for each lesions in patients who had more than one lesion, and treatment should plane according to these results.
authors.affiliation: Pulmonary Diseases, Faculty of Medicine, Osmangazi University, Eskişehir, Turkey. irfanucgun@hotmail.com
authors.forename: Irfan
authors.initials: I
authors.lastname: Uçgun
authors.forename: Ilknur
authors.initials: I
authors.lastname: Akçayir Sahin
authors.forename: Muzaffer
authors.initials: M
authors.lastname: Metintaş
authors.forename: Füsun
authors.initials: F
authors.lastname: Alataş
authors.forename: Sinan
authors.initials: S
authors.lastname: Erginel
authors.forename: Emine
authors.initials: E
authors.lastname: Dündar
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001999:Bronchoscopy; D018288:Carcinoma, Small Cell / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D018307:Neoplasms, Squamous Cell / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D012907:Smoking / Q000009:adverse effects; D014057:Tomography, X-Ray Computed