title: A 1,3-Diaza-Claisen rearrangement that affords guanidines.
abstract: [reaction: see text] N-Alkyl-N'-tosylthioureas activated by EDCI react with azanorbonenes at room temperature through a 1,3-diaza-Claisen rearrangement, affording highly substituted, bicyclic guanidines in moderate to good yields.
authors.affiliation: Department of Chemistry, University of Vermont, Burlington, Vermont 05405, USA.
authors.forename: Amy M
authors.initials: AM
authors.lastname: Bowser
authors.forename: José S
authors.initials: JS
authors.lastname: Madalengoitia
mesh_terms: D001372:Aza Compounds / Q000737:chemistry*; D002384:Catalysis; D006146:Guanidines / Q000032:analysis / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D015394:Molecular Structure; D009636:Norbornanes / Q000737:chemistry
chemical_list: D001372:Aza Compounds; D006146:Guanidines; D007202:Indicators and Reagents; D009636:Norbornanes