title: Methanogenic inhibition by arsenic compounds.
abstract: The acute acetoclastic methanogenic inhibition of several inorganic and organic arsenicals was assayed. Trivalent species, i.e., methylarsonous acid and arsenite, were highly inhibitory, with 50% inhibitory concentrations of 9.1 and 15.0 microM, respectively, whereas pentavalent species were generally nontoxic. The nitrophenylarsonate derivate, roxarsone, displayed moderate toxicity.
authors.affiliation: Department of Chemical and Environmental Engineering, University of Arizona, P.O. Box 210011, Tucson, AZ 85721-0011, USA. Rsierra@email.arizona.edu
authors.forename: Reyes
authors.initials: R
authors.lastname: Sierra-Alvarez
authors.forename: Irail
authors.initials: I
authors.lastname: Cortinas
authors.forename: Umur
authors.initials: U
authors.lastname: Yenal
authors.forename: Jim A
authors.initials: JA
authors.lastname: Field
mesh_terms: D001152:Arsenicals / Q000494:pharmacology*; D018053:Arsenites / Q000494:pharmacology; D019605:Euryarchaeota / Q000187:drug effects*; D007700:Kinetics; D012406:Roxarsone / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D001152:Arsenicals; D018053:Arsenites; D012406:Roxarsone; C015001:arsenite