A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation.
One pot microwave-assisted synthesis of substituted 1,2,4-oxadiazoles in solvent and under solvent free condition was performed exploring the importance of some coupling reagents. Good yields and short reaction times were the main aspects of the methods.
Santagada
Vincenzo
V
Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli 'Federico II', Via D. Montesano, 49, 80131 Naples, Italy. santagad@unina.it
Frecentese
Francesco
F
Perissutti
Elisa
E
Cirillo
Donatella
D
Terracciano
Sara
S
Caliendo
Giuseppe
G
D008872:Microwaves; D010069:Oxadiazoles / Q000138:chemical synthesis* / Q000528:radiation effects*
D010069:Oxadiazoles