title: Acrokeratosis paraneoplastica (Bazex syndrome): an atypical presentation.
abstract: A 62-year-old male presented with a 2-year history of hyperkeratotic lesions of the hands and feet. Previous treatment with topical steroids was unsuccessful. A complete physical examination revealed the presence of blood in the stool, and sigmoidoscopy showed an ulcerative growth at the rectosigmoid junction. The histopathology showed adenocarcinoma.
authors.affiliation: Department of Dermatology, Kasturba Medical College, Manipal, Karnataka India. jennyrao1@yahoo.com
authors.forename: Raghavendra
authors.initials: R
authors.lastname: Rao
authors.forename: Shrutakirthi D
authors.initials: SD
authors.lastname: Shenoi
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis; D000935:Antifungal Agents / Q000627:therapeutic use; D015725:Fluconazole / Q000627:therapeutic use; D005533:Foot Dermatoses / Q000209:etiology*; D006229:Hand Dermatoses / Q000209:etiology*; D006801:Humans; D017495:Hyperpigmentation / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009382:Neoplasms, Unknown Primary / Q000150:complications* / Q000175:diagnosis; D009780:Occult Blood; D014009:Onychomycosis / Q000150:complications / Q000188:drug therapy; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D011537:Pruritus / Q000209:etiology; D012004:Rectal Neoplasms / Q000150:complications* / Q000175:diagnosis; D012811:Sigmoid Neoplasms / Q000150:complications* / Q000175:diagnosis; D012812:Sigmoidoscopy
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole