A community-based study of common hereditary blood disorders in Oman.
We assessed the prevalence of three common hereditary blood disorders (sickle-cell and beta-thalassaemia traits and glucose 6-phosphate dehydrogenase deficiency) among the Omani population. We interviewed a representative sample of 6103 Omani households and blood samples from 6342 children aged 0-5 years were collected. About 27% of Omani males had inherited glucose-6-phosphate dehydrogenase deficiency (compared with 11% of females) while countrywide prevalence rates for the sickle-cell and beta-thalassaemia traits were estimated to be 5.8% and 2.2% respectively and showed no significant gender differences. There was a significant association between all three disorders and region of the country.
Al-Riyami
A A
AA
Department of Research and Studies, Ministry of Health, Muscat, Oman.
Suleiman
A J
AJ
Afifi
M
M
Al-Lamki
Z M
ZM
Daar
S
S
D000755:Anemia, Sickle Cell / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics; D002675:Child, Preschool; D003241:Consanguinity; D005260:Female; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics; D006306:Health Surveys; D006801:Humans; D007223:Infant; D008297:Male; D008403:Mass Screening; D009850:Oman / Q000453:epidemiology; D011159:Population Surveillance; D015995:Prevalence; D012111:Residence Characteristics / Q000706:statistics & numerical data; D012307:Risk Factors; D012529:Saudi Arabia / Q000453:epidemiology; D017678:Sex Distribution; D011795:Surveys and Questionnaires; D014479:United Arab Emirates / Q000453:epidemiology; D017086:beta-Thalassemia / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics