Effects of epilepsy surgery on psychiatric and behavioral comorbidities in children and adolescents.
When considering surgery in children, it is important to think about the potential effect on psychiatric and behavioral outcome. A growing body of evidence suggests that the type of epilepsy (benign or catastrophic) and the age of the patient affect developmental outcome. In younger children with catastrophic epilepsy, the primary goal of therapy is not only to control seizures, but also to offer the child the opportunity for the best possible development. In older children with partial seizures, the therapeutic goal is to control seizures, which may allow a more normal life and improve behavior. Epilepsy surgery generally appears to have a positive effect on behavior and development in many younger children with catastrophic epilepsy. Psychiatric and behavioral outcomes in older children with complex partial epilepsy are less clear; many patients improve, but there does appear to be a small risk of developing new psychiatric or behavioral disorders postoperatively.
Shields
W Donald
WD
Division of Pediatric Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1752, USA. wshields@mednet.ucla.edu
D000293:Adolescent; D001526:Behavioral Symptoms / Q000453:epidemiology*; D002648:Child; D015897:Comorbidity; D004827:Epilepsy / Q000453:epidemiology* / Q000601:surgery*; D006801:Humans; D005222:Mental Fatigue / Q000453:epidemiology*; D009493:Neurosurgery / Q000523:psychology; D011183:Postoperative Complications; D016896:Treatment Outcome