title: [Influence of Jieyu Huoxue Decoction on rehabilitation of patients with depression after cerebral infarction].
abstract: OBJECTIVE
  To study the influence of Jieyu Huoxue Decoction on rehabilitation of patients with depression after cerebral infarction.
  
  
  METHODS
  Fifty four patients suffered from the depression after acute cerebral infarction were randomly divided into three groups: depression control group, fluoxetine treated group and Jieyu Huoxue Decoction treated group. Eighteen patients of cerebral infarction without depression were enrolled in the no depression control group randomly. The Zung self-rating depression scale (SDS), the modified Edinburgh-Scandinavia stroke scale (MESSS) and the activities of daily living (ADL) were evaluated before treatment, 30 and 60 days after treatment.
  
  
  RESULTS
  After 30 and 60 days of treatment, SDS evaluation of the Jieyu Huoxue Decoction treated group showed significant difference as compared with the condition before treatment and that of the depression control group (P < 0.05 or P < 0.01), MESSS evaluation and ADL evaluation also showed significant difference as compared with the condition before treatment and that of the depression control group (P < 0.05 or P < 0.01); there was no obvious difference between the fluoxetine treated group and the Jieyu Huoxue Decoction treated group, but the Jieyu Huoxue Decoction treated group showed fewer symptoms and less side effect.
  
  
  CONCLUSIONS
  Jieyu Huoxue Decoction can not only relieve depression after cerebral infarction, but also improve neurological functions.
authors.affiliation: Department of Neurology, Shanghai Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai 200082, China. budfeng@yahoo.com.cn
authors.forename: Bei-Lei
authors.initials: BL
authors.lastname: Feng
authors.forename: Qiao-Chu
authors.initials: QC
authors.lastname: Wang
authors.forename: Zheng-Yuan
authors.initials: ZY
authors.lastname: Li
mesh_terms: D000368:Aged; D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use; D002544:Cerebral Infarction / Q000534:rehabilitation*; D003863:Depression / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D011237:Predictive Value of Tests; D016896:Treatment Outcome
chemical_list: D018687:Antidepressive Agents, Second-Generation; D004365:Drugs, Chinese Herbal; D010936:Plant Extracts; D005473:Fluoxetine