title: Diffusion tensor imaging in frontal lobe epilepsy.
abstract: We report a 13-year-old female with refractory frontal lobe epilepsy in whom diffusion tensor imaging was useful for exploring subtle cortical malformation. She had frequent simple partial seizures characterized by clonic movement of the right upper extremity. Conventional magnetic resonance imaging was not conclusive. A diffusion tensor imaging revealed an increased apparent diffusion coefficient and reduced anisotropy in the left frontal lobe. Positron emission tomography disclosed hypermetabolism in the adjacent area. We could identify the relatively thick cortex with an indistinct gray-white matter junction in a thin-slice T(1)-weighted image.
authors.affiliation: Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors.forename: Akihisa
authors.initials: A
authors.lastname: Okumura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Fukatsu
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Kato
authors.forename: Taketo
authors.initials: T
authors.lastname: Ikuta
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Watanabe
mesh_terms: D000293:Adolescent; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D017034:Epilepsy, Frontal Lobe / Q000473:pathology* / Q000503:physiopathology*; D005260:Female; D006801:Humans