Ketamine for long-term sedation and analgesia of a burn patient.
We present a case in which ketamine was used for long-term sedation and analgesia of a burn patient. Under escalating opiate dosages, the patient had developed persistent ileus as well as abdominal distension that caused respiratory compromise, without receiving sufficient analgesia. The opiate-sparing effect of the continuous ketamine infusion was more than 90%. The ileus resolved within 24 h. The quality of sedation also changed favorably. There were no obvious adverse effects of ketamine.
Edrich
Thomas
T
*Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; and †Department of Anesthesiology and Intensive Care Medicine, Tübingen University Hospital, Tübingen, Germany.
Friedrich
Andrew D
AD
Eltzschig
Holger K
HK
Felbinger
Thomas W
TW
D000328:Adult; D000700:Analgesics / Q000627:therapeutic use*; D002056:Burns / Q000188:drug therapy*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D007649:Ketamine / Q000627:therapeutic use*; D008297:Male
D000700:Analgesics; D006993:Hypnotics and Sedatives; D007649:Ketamine