title: [Treatment with sildenafil of cold glands syndrome after inflatable penile prosthesis].
abstract: OBJECTIVE
  To evaluate the effect of sildenafil on the response of glans penis during sexual intercourse in patients with penile prosthesis who show cold glans syndrome symptoms.
  
  
  METHODS
  Fourteen patients who had undergone three-piece inflatable penile prosthesis implantation were evaluated. In spite of the normal functioning of the device all of them complained of a degree of dissatisfaction during SI due to a lack of engorgement in the glans penis. The patients were advised to have a dose of 100 mg VO sildenafil about 45 minutes before activating the PP and starting SI. All of them followed this scheme at least three times. They ticked questions 7, 8, 13 and 14 of the International Index of Erectile Function (IIEF) questionnaire with/without having had sildenafil.
  
  
  RESULTS
  Twelve out of thirteen patients (85.7%) indicated a more pleasant SI on sildenafil. It was related to an increase in penile glans engorgement and sensitivity. The scores obtained in the IIEF questions showed a significant increase on taking sildenafil. The partners also talked of a more comfortable SI that they related to a less painful penetration. Sildenafil-related morbidity was not found.
  
  
  CONCLUSIONS
  Sildenafil could be used to improve functional results of the penile prosthesis in those patients with CGS and seems to increase satisfaction during SI.
authors.affiliation: Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid.
authors.forename: E
authors.initials: E
authors.lastname: Lledó García
authors.forename: I
authors.initials: I
authors.lastname: Moncada Iribarren
authors.forename: J
authors.initials: J
authors.lastname: Jara Rascón
authors.forename: C
authors.initials: C
authors.lastname: Carrera Puerta
authors.forename: F
authors.initials: F
authors.lastname: González-Chamorro
authors.forename: C
authors.initials: C
authors.lastname: Llorente Abarca
authors.forename: C
authors.initials: C
authors.lastname: Hernández Fernández
mesh_terms: D001831:Body Temperature; D003080:Cold Temperature; D006801:Humans; D008297:Male; D015917:Penile Prosthesis / Q000009:adverse effects*; D010413:Penis; D010879:Piperazines / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000188:drug therapy*; D011446:Prospective Studies; D011687:Purines; D000068677:Sildenafil Citrate; D013450:Sulfones; D013577:Syndrome; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate