Improvement of sensitivity in the determination of organochlorine pesticides using a PSS injector with GC-ECD.
This paper describes the optimisation of a PSS injector in a gas chromatograph with a programmed pneumatic control (PPC) for the determination of 21 organochlorine pesticides. The injection of high volumes of sample (20 microl) improves the detection limits and allows a reduction in the amount of sample processed. The injection conditions were selected by a Plackett-Burman design followed by a central composite design. The LODs obtained in the optimum conditions were compared with those obtained with splitless/ECD. Finally, the method was successfully applied to the analysis of a leachate and vegetable samples.
Concha-Graña
E
E
Department of Analytical Chemistry, University of A Coruña, Campus da Zapateira, 15071 A Coruña, Spain.
Turnes-Carou
M I
MI
Muniategui-Lorenzo
S
S
López-Mahía
P
P
Fernández-Fernández
E
E
Prada-Rodríguez
D
D
D002849:Chromatography, Gas / Q000295:instrumentation / Q000379:methods; D006843:Hydrocarbons, Chlorinated / Q000032:analysis*; D010575:Pesticides / Q000032:analysis*; D012680:Sensitivity and Specificity; D013997:Time Factors
D006843:Hydrocarbons, Chlorinated; D010575:Pesticides