Current vaccine adjuvants: an overview of a diverse class.
Numerous compounds are under evaluation as immunological adjuvants for improvement of vaccine performance. This review will briefly summarize some of the many diverse substances that are currently being utilized as vaccine adjuvants in preclinical and clinical studies.
Kensil
Charlotte Read
CR
Antigenics, Inc., 3 Forbes Road, Lexington, MA 02421, USA.
Mo
Annie Xiaoyan
AX
Truneh
Alemseged
A
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D018899:CpG Islands; D016207:Cytokines / Q000378:metabolism; D006133:Growth Substances / Q000378:metabolism; D006360:Heat-Shock Proteins / Q000378:metabolism; D006801:Humans; D007107:Immune System; D007111:Immunity, Cellular; D018928:Immunity, Mucosal; D007155:Immunologic Factors / Q000737:chemistry; D008070:Lipopolysaccharides / Q000737:chemistry; D008074:Lipoproteins / Q000737:chemistry; D010457:Peptidoglycan / Q000737:chemistry; D011994:Recombinant Proteins / Q000737:chemistry; D012503:Saponins / Q000737:chemistry; D014612:Vaccines / Q000627:therapeutic use*; D019444:Vaccines, DNA
D000276:Adjuvants, Immunologic; D016207:Cytokines; D006133:Growth Substances; D006360:Heat-Shock Proteins; D007155:Immunologic Factors; D008070:Lipopolysaccharides; D008074:Lipoproteins; D010457:Peptidoglycan; D011994:Recombinant Proteins; D012503:Saponins; D014612:Vaccines; D019444:Vaccines, DNA