title: Somatostatin receptor scintigraphy in MALT lymphoma of the lacrimal gland treated with rituximab.
abstract: Non-gastric stage I extranodal marginal zone lymphomas of MALT are usually treated with local therapy. However, distant relapses in other extranodal sites are not uncommon suggesting under-staging of these patients using conventional image studies. Positron emission tomography (PET) scans are frequently negative in this subgroup of patients with lymphoma and therefore do not significantly contribute to the staging process. We present a case of lacrimal gland MALT lymphoma demonstrating the usefulness of somatostatin receptor scintigraphy for initial staging and evaluation of response to treatment.
authors.affiliation: Hematology/Oncology Division, University of Miami/Sylvester Cancer Center. Miami, FL 33136, USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: Morgensztern
authors.forename: Manuel F
authors.initials: MF
authors.lastname: Rosado
authors.forename: Aldo N
authors.initials: AN
authors.lastname: Serafini
authors.forename: Izidore S
authors.initials: IS
authors.lastname: Lossos
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D058846:Antibodies, Monoclonal, Murine-Derived; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005134:Eye Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D007766:Lacrimal Apparatus Diseases / Q000000981:diagnostic imaging* / Q000188:drug therapy; D018442:Lymphoma, B-Cell, Marginal Zone / Q000000981:diagnostic imaging* / Q000188:drug therapy; D009367:Neoplasm Staging; D015282:Octreotide / Q000031:analogs & derivatives*; D004369:Pentetic Acid / Q000031:analogs & derivatives*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin / Q000378:metabolism; D000069283:Rituximab; D014055:Tomography, Emission-Computed
chemical_list: D000911:Antibodies, Monoclonal; D058846:Antibodies, Monoclonal, Murine-Derived; D000970:Antineoplastic Agents; D007205:Indium Radioisotopes; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin; C071632:SDZ 215-811; D000069283:Rituximab; D004369:Pentetic Acid; D015282:Octreotide