[Primary juvenile glaucoma--clinical and genetic aspects].
OBJECTIVE
We have done a retrospective study of juvenile glaucoma cases hospitalized between 1993-2002.


METHODS
52 primary juvenile glaucoma patients were available for our clinical and genealogical investigations.


RESULTS
In this study we have analyzed the distribution of cases per year, the age of appearance of the diseases, and the distribution in function of the sex and the genealogical factors. Genealogic analyze was performed by statistical methods: Weinberg and penetrance.


CONCLUSIONS
Under 16 years, juvenile glaucoma diagnosis was mostly established by examining the children for visual acuity disorders caused by different ametropies, especially progressive rapid myopia. Genealogical exams confirmed an autosomal recessive transmission with incomplete variable penetrance but the possibility of polygenic multifactorial heredity may be also considered.
Bărăscu
Doina
D
Clinica de Oftalmologie, Spitalul de Urgenţă Craiova.
Olaru
C
C
State
Anca
A
D000293:Adolescent; D000328:Adult; D000465:Algorithms; D002648:Child; D002675:Child, Preschool; D005260:Female; D005901:Glaucoma / Q000175:diagnosis* / Q000235:genetics*; D006801:Humans; D008297:Male; D009216:Myopia / Q000209:etiology; D010375:Pedigree; D012189:Retrospective Studies; D035781:Siblings