title: A facile synthesis of C2,N3-disubstituted-4-quinazolone.
abstract: A simple and efficient methodology for the synthesis of C(2),N(3)-disubstituted-4 quinazolones from anilines and N-acylanthranilic acids was developed. The new cyclization conditions are much milder than any other reported protocols and resulted in excellent yields (87-98%) without chromatography.
authors.affiliation: Chemical and Analytical Development, Novartis Institute for Biomedical Research, East Hanover, New Jersey 07936, USA. song.xue@pharma.novartis.com
authors.forename: Song
authors.initials: S
authors.lastname: Xue
authors.forename: Joseph
authors.initials: J
authors.lastname: McKenna
authors.forename: Wen-Chung
authors.initials: WC
authors.lastname: Shieh
authors.forename: Oljan
authors.initials: O
authors.lastname: Repic