title: Optimal target international normalized ratio for patients with mechanical heart valves.
authors.forename: Johanna J M
authors.initials: JJ
authors.lastname: Takkenberg
authors.forename: John P A
authors.initials: JP
authors.lastname: Puvimanasinghe
authors.forename: Lex A
authors.initials: LA
authors.lastname: van Herwerden
mesh_terms: D001021:Aortic Valve; D006331:Heart Diseases / Q000517:prevention & control*; D006350:Heart Valve Prosthesis; D006801:Humans; D019934:International Normalized Ratio / Q000592:standards*; D008943:Mitral Valve; D013923:Thromboembolism / Q000517:prevention & control*; D014812:Vitamin K / Q000037:antagonists & inhibitors*
chemical_list: D014812:Vitamin K