[Molecular aspects of the damaging action of bacterial lipopolysaccharides].
The review deals with the molecular aspects of the interaction of bacterial lipopolysaccharides (LPS, with the macroorganism: the sources of LPS in the organism, its detoxication, regulation disturbances in pathology (septic shock). Special attention is drawn to the complex functioning of cytokines in the development of the inflammatory process both at the initial stage, characterized by the initiation of the cytokine cascade and at the final stage resulting in convalescence or the development of pathology. The most promising trends of research in this field are discussed.
Riabichenko
E V
EV
Vetkova
L G
LG
Bondarenko
V M
VM
D000818:Animals; D001424:Bacterial Infections / Q000276:immunology* / Q000382:microbiology*; D016207:Cytokines / Q000276:immunology; D006801:Humans; D008070:Lipopolysaccharides / Q000276:immunology*; D037521:Virulence Factors / Q000276:immunology*
D016207:Cytokines; D008070:Lipopolysaccharides; D037521:Virulence Factors