[Morphological features of chronic viral hepatitis in drug addicts].
Liver pathology in parenteral drug abusers (PDA) was studied morphometrically. Chronic hepatitis in PDA is characterized by high incidence of lymphoid follicles formation in the portal tracts and intralobularly, relatively low activity of portal hepatitis in significant expression of the lobular component of the inflammatory process, marked fibrosis and early formation of micronodular liver cirrhosis, noticeable proliferation of narrow bile ducts, high content of neutrophils, eosinophils, siderophages and common macrophages in the infiltrate and their granuloma-like accumulations in the portal tracts. These criteria are recommended for diagnosis of drug abuse by morphological data. The use of a morphometrical method is proposed for studying morphological manifestations of chronic hepatitis, for perfection of their classification, in particular.
Pigolkin
Iu I
IuI
Bogomolov
D V
DV
Bogomolova
I N
IN
Sergeeva
L A
LA
D000293:Adolescent; D000328:Adult; D005260:Female; D019694:Hepatitis B, Chronic / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D019698:Hepatitis C, Chronic / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D019701:Hepatitis D, Chronic / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology; D008297:Male; D019966:Substance-Related Disorders / Q000150:complications*