[Investigation of an outbreak of acute diarrhea caused by Human calicivirus].
BACKGROUND
To survey a diarrhea outbreak in Guangan city and analyze the cause of the disease.


METHODS
The population enrolled in the surveillance came from four different settings and was randomly sampled. Stool specimens collected from diarrhea patients were tested ordinarily for enteric bacteria and further examined for viral pathogens with PAGE, ELISA and RT-PCR.


RESULTS
In total, 4,567 persons were surveyed, among them 942 had acute diarrhea (prevalence 20.63%). The incidence was higher in rural area (28.6%) than in urban area (19.6%) (chi-square =22.29, P less than 0.005) with a peak in May 10 through 25 four human caliciviruses were detected from stool specimens by ELISA and RT-PCR in specimens from 4 and 1 patients, respectively.


CONCLUSIONS
Human calicivirus probably was the cause of this diarrhea outbreak in Guangan city.
Li
Wen-zhang
WZ
Guangan Hygiene and Antiepidemic Station, Sichuan Province, Guangan 638000, China.
Xie
Hua-ping
HP
Wu
Hai-yan
HY
Zhou
Dao-yun
DY
Zheng
Li-shu
LS
Cai
Yun-shan
YS
Kang
You-ling
YL
Jiang
Xi
X
Fang
Zhao-yin
ZY
D000208:Acute Disease / Q000453:epidemiology; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D017250:Caliciviridae Infections / Q000453:epidemiology* / Q000821:virology; D002648:Child; D002681:China / Q000453:epidemiology; D003967:Diarrhea / Q000453:epidemiology* / Q000821:virology*; D004196:Disease Outbreaks; D005243:Feces / Q000821:virology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D029322:Norovirus / Q000302:isolation & purification*; D055815:Young Adult