title: Myxomatous lesions of the maxilla in children: a case series and review of management.
abstract: OBJECTIVE
  A paucity of data exists in the literature regarding the pediatric bony myxoma. Controversy exists regarding both its histopathologic origins and surgical management. The purpose of this study was to report on our experience in managing these patients, including diagnostic work-up, histopathologic findings and an evaluation of surgical treatment outcomes.
  
  
  METHODS
  A retrospective review was undertaken of all consecutive cases of pediatric bony myxoma treated between 1988 and 2001. Tumors were analyzed in terms of clinical data, imaging studies, histopathology and surgical treatment. A selective review of the literature regarding management of the bony myxoma is also presented.
  
  
  RESULTS
  Five lesions were identified, all of which occurred in the maxillary bone. Histopathologically our cases did not show a strong association with odontogenic epithelium. All cases were treated by surgical resection with conservative margins. No recurrences were documented over a mean follow-up period of 8.5 years.
  
  
  CONCLUSIONS
  The bony myxoma is a rare lesion in the pediatric population, and initial clinical or radiological misdiagnoses are not uncommon. The presupposed odontogenic origin of these tumors may need reassessment. Conservative resection with narrow margins is a safe and effective therapy for myxomas of the pediatric maxilla.
authors.affiliation: Department of Otolaryngology, The Hospital for Sick Children, Elm Wing 6th Floor, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8.
authors.forename: Brian W
authors.initials: BW
authors.lastname: Rotenberg
authors.forename: Sam J
authors.initials: SJ
authors.lastname: Daniel
authors.forename: Iain A
authors.initials: IA
authors.lastname: Nish
authors.forename: Bo Y
authors.initials: BY
authors.lastname: Ngan
authors.forename: Vito
authors.initials: V
authors.lastname: Forte
mesh_terms: D000293:Adolescent; D001706:Biopsy; D002648:Child; D003937:Diagnosis, Differential; D018572:Disease-Free Survival; D005260:Female; D005350:Fibroma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008297:Male; D008441:Maxillary Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D008444:Maxillary Sinus Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D009232:Myxoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome