One-pot oligosaccharide synthesis: reactivity tuning by post-synthetic modification of aglycon.
Post-synthetic aglycon modification of substituted aryl thioglycosides led to building blocks with multiple levels of anomeric reactivities, which can be used in rapid assembly of oligosaccharides in one-pot syntheses.
Huang
Lijun
L
Department of Chemistry, University of Toledo, 2801 W. Bancroft Street, MS 602, Toledo, OH 43606, USA.
Wang
Zhen
Z
Huang
Xuefei
X
D000970:Antineoplastic Agents / Q000494:pharmacology*; D006031:Glycosylation; D006841:Hydrocarbons, Aromatic / Q000737:chemistry; D008956:Models, Chemical; D009844:Oligosaccharides / Q000138:chemical synthesis*; D013865:Thioglycosides / Q000737:chemistry*
D000970:Antineoplastic Agents; D006841:Hydrocarbons, Aromatic; D009844:Oligosaccharides; D013865:Thioglycosides