title: Synthesis of diazepinones via intramolecular transamidation.
abstract: [structure: see text] The synthesis of a collection of bicyclic fused azepinones via an intramolecular beta-lactam ring-opening strategy is reported. Depending on the chirality of the various inputs, complete stereocontrol of product formation is achieved.
authors.affiliation: Enabling Chemistry Technologies, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064, USA. anil.vasudevan@@abbott.com
authors.forename: Anil
authors.initials: A
authors.lastname: Vasudevan
authors.forename: Clara I
authors.initials: CI
authors.lastname: Villamil
authors.forename: Stevan W
authors.initials: SW
authors.lastname: Djuric