[The effect of static magnetic field on bone morphogenetic protein-2 in periodontal membrane of the rat].
OBJECTIVE
The purpose of this study is to evaluate the effect of static magnetic field on the expression of BMP-2 in the periodontal membrane of rat.


METHODS
35 female rats of wistar were randomly divided into three groups, which were the normal group, experimental control group and experimental group. The experimental rat's cheeks were put into magnet with the intensity of magnetic field being 0.12 tesla. The rats were sacrificed at 2 days, 4 days, 7 days, respectively. Immunohistochemical assays were used to evaluate the changes of BMP-2 expression in the periodontal membrane of the maxillary molars.


RESULTS
BMP-2 was mainly found in the plasma of fibroblast, osteoblast, cementocyte, odontoblast separately. There were more BMP-2 in the experimental group treated with static magnetic field. There were significant differences between the experiment group of 4 day and 7 day and the control group.


CONCLUSIONS
Static magnetic field stimulated BMP-2 secreted by the cell of periodontal membrane and played an important role in repairing and remodeling of periodontitis.
Qin
Ke
K
College of Stomatology, China Medical University, Shenyang 110002, Liaoning Province, China. drqinke@sina.com
Qiu
Li-Hong
LH
Zhong
Ming
M
Wang
Zhao-Yuan
ZY
D000818:Animals; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins / Q000096:biosynthesis* / Q000528:radiation effects; D004574:Electromagnetic Fields; D005260:Female; D010513:Periodontal Ligament / Q000378:metabolism* / Q000528:radiation effects; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D016212:Transforming Growth Factor beta / Q000096:biosynthesis* / Q000528:radiation effects
C525720:Bmp2 protein, rat; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins; D016212:Transforming Growth Factor beta