Clinical significance of increased cardiac troponins T and I in participants of ultra-endurance events.
Of 105 asymptomatic finishers of endurance competitive events lasting several hours, increased blood concentrations of cardiac troponins T and I above the 99% upper reference values were found in 24 and 34 subjects, respectively; N-terminal pro-brain natriuretic peptide was also significantly increased. Within 3 months after the events, 21 troponin-positive participants underwent an extensive cardiac examination, which in all but 1 (critical coronary heart disease) revealed no signs of persistent cardiac damage.
Urhausen
Axel
A
Institute of Sports and Preventive Medicine, University of Saarland, Saarbrücken, Germany. a.urhausen@rz.uni-sb.de
Scharhag
Jürgen
J
Herrmann
Markus
M
Kindermann
Wilfried
W
D000328:Adult; D001642:Bicycling / Q000502:physiology; D005260:Female; D006334:Heart Function Tests / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*; D020097:Natriuretic Peptide, Brain; D009336:Necrosis; D009419:Nerve Tissue Proteins / Q000097:blood; D010446:Peptide Fragments / Q000097:blood; D010807:Physical Endurance / Q000502:physiology*; D012420:Running / Q000502:physiology; D013177:Sports / Q000502:physiology*; D019210:Troponin I / Q000097:blood*; D020107:Troponin T / Q000097:blood*
D009419:Nerve Tissue Proteins; D010446:Peptide Fragments; D019210:Troponin I; D020107:Troponin T; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain