[Phenotypical analysis of heterogenic Vibrio cholerae strain Dacca 35 Ogawa].
The comparative analysis of the production of the main pathogenicity factors by toxigenic and non-toxigenic clones of V. cholerae natural classical strain Dacca 35 Ogawa has been carried out. The data obtained in this analysis indicate that the appearance of turbid colonies, not synthesing cholera toxin, is linked with the production of an exopolysaccharide layer on the outer surface of the cells, which determines their morphology. The suggestion has been made that the regulatory gene toxR controls the expression of not only cholera toxin, protein OmpU, but also exopolysaccharide.
Zadnova
S P
SP
Toporkov
A V
AV
Isaev
N D
ND
D000372:Agglutination Tests; D001426:Bacterial Proteins / Q000032:analysis / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000032:analysis / Q000378:metabolism*; D004587:Electrophoresis, Agar Gel; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D008854:Microscopy, Electron; D010641:Phenotype; D011135:Polysaccharides, Bacterial / Q000032:analysis / Q000378:metabolism*; D014157:Transcription Factors / Q000032:analysis / Q000378:metabolism*; D014734:Vibrio cholerae / Q000235:genetics* / Q000378:metabolism* / Q000472:pathogenicity; D037521:Virulence Factors / Q000032:analysis / Q000378:metabolism*
D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; D011135:Polysaccharides, Bacterial; D014157:Transcription Factors; D037521:Virulence Factors; C499324:toxR protein, Vibrio cholerae; C066719:toxR protein, bacteria