title: Long-term therapy with organic nitrates: the pros and cons of nitric oxide replacement therapy.
authors.forename: Tommaso
authors.initials: T
authors.lastname: Gori
authors.forename: John D
authors.initials: JD
authors.lastname: Parker
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000009:adverse effects / Q000378:metabolism* / Q000494:pharmacology* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004361:Drug Tolerance; D004730:Endothelium, Vascular / Q000187:drug effects*; D006801:Humans; D007548:Isosorbide Dinitrate / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000378:metabolism* / Q000494:pharmacology* / Q000627:therapeutic use; D009566:Nitrates / Q000378:metabolism / Q000494:pharmacology; D020030:Nitric Oxide Donors / Q000009:adverse effects / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D010084:Oxidation-Reduction / Q000187:drug effects; D011355:Prodrugs / Q000378:metabolism / Q000494:pharmacology; D013997:Time Factors
chemical_list: D000975:Antioxidants; D009566:Nitrates; D020030:Nitric Oxide Donors; D011355:Prodrugs; D007548:Isosorbide Dinitrate; C030397:isosorbide-5-mononitrate