Gemcitabine and oxaliplatinum: an effective regimen in a patient with progressive refractory mantle cell lymphoma.
We report here a 68-year-old man with progressive refractory Mantle cell Lymphoma stage IV-A, treated with different chemotherapeutic drugs. With no therapeutic options we decided to treat him with oxaliplatinum-gemcitabine regimen, based on the proven efficacy and synergy of these drugs in other tumors and lymphomas. Treatment was well tolerated and patient achieved a maintained complete remission with 6 months of follow up. We consider that this may be a salvage therapeutic option for patients with mantle cell lymphoma.
Sampol
A
A
Servicio de Hematologia, Hospital Universitario Son Dureta, Palma de Mallorca, Islas Baleares, Spain.
Rodriguez
J
J
Galmés
B
B
Gutierrez
A
A
Besalduch
J
J
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D018450:Disease Progression; D006801:Humans; D020522:Lymphoma, Mantle-Cell / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy*; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D000077150:Oxaliplatin; D016879:Salvage Therapy; D000093542:Gemcitabine
D009944:Organoplatinum Compounds; D000077150:Oxaliplatin; D003841:Deoxycytidine; D000093542:Gemcitabine