title: Pyridoxine-dependent seizures and microcephaly.
abstract: Pyridoxine dependency is a rare autosomal-recessive disorder causing intractable seizures in neonates and infants. This case report describes an infant with pyridoxine-dependent seizures with microcephaly and discusses a probable pathogenetic mechanism of microcephaly in this condition.
authors.affiliation: Department of Child Neurology, Yakutiye Research Hospital, Atatürk University, Faculty of Medicine, Erzurum, Turkey.
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Tan
authors.forename: Fatih
authors.initials: F
authors.lastname: Kardaş
authors.forename: Mustafa
authors.initials: M
authors.lastname: Büyükavci
authors.forename: Cahit
authors.initials: C
authors.lastname: Karakelleoğlu
mesh_terms: D006801:Humans; D007223:Infant; D008297:Male; D008831:Microcephaly / Q000150:complications / Q000188:drug therapy / Q000209:etiology*; D011736:Pyridoxine / Q000008:administration & dosage / Q000627:therapeutic use*; D012640:Seizures / Q000150:complications / Q000188:drug therapy / Q000209:etiology*
chemical_list: D011736:Pyridoxine