title: Traumatic partial hypopituitarism in a cat.
abstract: Traumatic hypopituitarism was diagnosed in an 11-month-old male neutered cat. The presenting complaints were polydipsia, polyuria and lethargy of three months' duration. Craniocerebral trauma, as a result of a road traffic accident, had preceded the onset of clinical signs by six weeks. Neurological examination revealed right-sided mydriasis, reduced visual and tactile left forelimb placing reflexes and decreased proprioception in both the left fore- and hindlimb. Initial laboratory findings included hypernatraemia, hyperchloraemia, mild azotaemia, eosinophilia and isosthenuria. Low basal cortisol, thyroxine, thyroid-stimulating hormone and insulin growth factor-1 were noted. Subsequent to treatment with prednisolone, a water deprivation test confirmed the presence of central diabetes insipidus and therapy with synthetic antidiuretic hormone successfully ameliorated the polydipsia.
authors.affiliation: Davies White Veterinary Specialists, Manor Farm Business Park, Higham Gobion, Hertfordshire.
authors.forename: J R
authors.initials: JR
authors.lastname: Smith
authors.forename: C M
authors.initials: CM
authors.lastname: Elwood
mesh_terms: D000063:Accidents, Traffic; D000309:Adrenal Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000662:veterinary*; D000818:Animals; D002371:Cat Diseases / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D002415:Cats; D006259:Craniocerebral Trauma / Q000150:complications / Q000662:veterinary*; D003919:Diabetes Insipidus / Q000175:diagnosis / Q000209:etiology / Q000662:veterinary*; D003937:Diagnosis, Differential; D008297:Male; D014667:Vasopressins / Q000627:therapeutic use
chemical_list: D014667:Vasopressins