title: Perinatal outcome of pregnancies complicated by placenta accreta.
abstract: OBJECTIVE
  The purpose of the study was to characterize the perinatal outcome of pregnancies complicated by placenta accreta.
  
  
  METHODS
  We conducted a case-control analysis of all deliveries between the years 1990 and 2000 that were complicated by placenta accreta. Perinatal variables included in the analysis were gestational age at delivery, birth weight, Apgar scores, and perinatal mortality. Statistical analysis was performed using both the unpaired and paired approach. P <.05 was considered significant.
  
  
  RESULTS
  The study encompassed 34,450 deliveries, from which 310 cases of placenta accreta were diagnosed (0.9%) and compared with 310 matched controls. In the pregnancies complicated by placenta accreta, we found a statistically significant increase in preterm deliveries (10.7% versus 1%, P <.001, odds ratio 12.1, 95% confidence interval 3.7-39.9) and small-for-gestational-age babies (27.3% versus 14%, P <.001, odds ratio 5.05, 95% confidence interval 1.46-3.28).
  
  
  CONCLUSIONS
  Pregnancies complicated by placenta accreta are at increased risk for perinatal adverse outcome. We speculate that these findings may arise from pathological implantation of the placenta, resulting in interference with normal fetal growth.
authors.affiliation: Department of Obstetrics and Gynecology, Hadassah Medical Center, The Hebrew University, Jerusalem, Israel. yuvalgi@attglobal.net
authors.forename: Yuval
authors.initials: Y
authors.lastname: Gielchinsky
authors.forename: David
authors.initials: D
authors.lastname: Mankuta
authors.forename: Nathan
authors.initials: N
authors.lastname: Rojansky
authors.forename: Neri
authors.initials: N
authors.lastname: Laufer
authors.forename: Ilan
authors.initials: I
authors.lastname: Gielchinsky
authors.forename: Yossef
authors.initials: Y
authors.lastname: Ezra
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D010921:Placenta Accreta; D011247:Pregnancy; D011256:Pregnancy Outcome