title: [The problem of optimization in cardiology].
abstract: Optimization is understood as choice of the best version out of the competitive decisions. The strategy and tactics of prevention is presented from this point of view. Optimization of diagnostic investigations is viewed from the positions of continuum with quantitative assessment of results. Characteristics of loads and heart activity, as recommendations suggest, should be in agreement in stress tests. Optimization of dynamic investigations of biochemical markers is described on the model of acute coronary syndrome. Optimization of therapy is based on the determination of criteria of optimum. This statement is illustrated by the example of antihypertensive therapy. Optimization of pharmacotherapy must envisage the preservation of favorable effect of protective natural mechanisms in the form of autoregulation and adaptation to intermittent ischemia (preconditioning).
authors.affiliation: National Research and Practical Center "Cardiology", Minsk, Republic of Belarus.
authors.forename: G I
authors.initials: GI
authors.lastname: Sidorenko
mesh_terms: D002309:Cardiology; D006801:Humans; D007511:Ischemia; D017202:Myocardial Ischemia