title: Strongylophorine-26, a new meroditerpenoid isolated from the marine sponge Petrosia (Strongylophora) corticata that exhibits anti-invasion activity.
abstract: Strongylophorine-26 (1), a new meroditerpenoid that shows activity in an anti-invasion assay, has been isolated from the marine sponge Petrosia (Strongylophora) corticata collected in Papua New Guinea. The structure of 1 was elucidated by analysis of spectroscopic data.
authors.affiliation: Department of Chemistry, University of British Columbia, Vancouver, B.C. V6T 1Z1, Canada.
authors.forename: Kaoru
authors.initials: K
authors.lastname: Warabi
authors.forename: Lianne M
authors.initials: LM
authors.lastname: McHardy
authors.forename: Lohi
authors.initials: L
authors.lastname: Matainaho
authors.forename: Rob
authors.initials: R
authors.lastname: Van Soest
authors.forename: Calvin D
authors.initials: CD
authors.lastname: Roskelley
authors.forename: Michel
authors.initials: M
authors.lastname: Roberge
authors.forename: Raymond J
authors.initials: RJ
authors.lastname: Andersen
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010219:Papua New Guinea; D011161:Porifera / Q000737:chemistry*; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D004224:Diterpenes; C491871:strongylophorine-26