title: [Leptospirosis--epidemic, clinical and diagnostic aspects].
abstract: Leptospirosis is a major public health problem throughout the world. We studied 22 cases of leptospirosis. They were hospitalised between 1999-2003. Men were more affected than women and those with rural origin prevailed, too. The direct infection was more often found in these cases. These patients presented a large spectrum of signs and symptoms attributable to this spirochetal pathogen. The etiology was dominated by L. pomona, L. canicola, L. wolffi. Leptospirosis presented with 3 syndromes: Weil's syndrome, atypical pneumonia syndrome and aseptic meningitis. The adequate treatment was with penicillin or ampicillin i.v.
authors.affiliation: Universitatea de Medicină şi Farmacie Târgu Mureş.
authors.forename: Anca
authors.initials: A
authors.lastname: Sipoş
authors.forename: Felicia
authors.initials: F
authors.lastname: Toma
authors.forename: Farkas
authors.initials: F
authors.lastname: Judit
authors.forename: Monica
authors.initials: M
authors.lastname: Dănilă
authors.forename: R
authors.initials: R
authors.lastname: Sipoş
mesh_terms: D000293:Adolescent; D000328:Adult; D000667:Ampicillin / Q000627:therapeutic use; D000818:Animals; D000890:Anti-Infective Agents / Q000627:therapeutic use; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007919:Leptospira / Q000302:isolation & purification*; D007922:Leptospirosis / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D008297:Male; D016920:Meningitis, Bacterial / Q000382:microbiology; D008875:Middle Aged; D010406:Penicillins / Q000627:therapeutic use; D018410:Pneumonia, Bacterial / Q000382:microbiology; D012189:Retrospective Studies; D012383:Romania / Q000453:epidemiology; D016896:Treatment Outcome; D014895:Weil Disease / Q000382:microbiology
chemical_list: D000890:Anti-Infective Agents; D004338:Drug Combinations; D010406:Penicillins; D000667:Ampicillin