title: Use of the n-butyl cyanoacrylate adhesive and the polyglactine thread suture for corneal rhaphy in rabbit (Oryctolagus cunicullus).
abstract: The aim of this study was to evaluate the cicatricial repair of perforating cornea in rabbits, by using the N-butyl cyanoacrylate adhesive compared to the 910-polyglactine thread suture through macroscopic and histological assays. Corneas from 18 adult rabbits were perforated and subsequently occluded with N-butyl cyanoacrylate synthetic adhesive (right cornea) or by separated single points using the 910-polyglactine thread (left cornea). The rabbits were divided into groups containing three animals per group. Examination after 7, 15, and 30 days post-operative showed that both the synthetic adhesive and the suture were efficient in the occlusion of the surgical wounds, thus stabilizing the intra-ocular content. The N-butyl cyanoacrylate adhesive was shown to be superior to the 910-polyglactine suture thread with regards to the evolution and the organization of the healing process.
authors.affiliation: College of Veterinary Medicine, Federal University of Uberlandia, Minas Gerais, Brasil. dantasmota@yahoo.com.br
authors.forename: Francisco Cláudio Dantas
authors.initials: FC
authors.lastname: Mota
authors.forename: Duvaldo
authors.initials: D
authors.lastname: Eurides
authors.forename: Patricia Maria Coletto
authors.initials: PM
authors.lastname: Freitas
authors.forename: Marcelo Emílio
authors.initials: ME
authors.lastname: Beletti
authors.forename: Michelle Rodriques
authors.initials: MR
authors.lastname: Goulart
authors.forename: Lívia Maria Ferreira
authors.initials: LM
authors.lastname: Cunha
authors.forename: Luiz Antonio Franco
authors.initials: LA
authors.lastname: da Silva
authors.forename: Maria Clorinda Soares
authors.initials: MC
authors.lastname: Fioravanti
mesh_terms: D000818:Animals; D003315:Cornea / Q000601:surgery*; D065306:Corneal Injuries; D004659:Enbucrilate / Q000627:therapeutic use*; D005260:Female; D008297:Male; D011098:Polyglactin 910 / Q000627:therapeutic use; D011817:Rabbits / Q000601:surgery*; D013537:Sutures; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014945:Wound Healing
chemical_list: D014014:Tissue Adhesives; D011098:Polyglactin 910; D004659:Enbucrilate