title: Investigation of Keyes skin biopsy instrument for intestinal biopsy versus a standard biopsy technique.
abstract: A prospective, clinical trial was conducted using 12 dogs that were presented for intestinal biopsy. Comparisons were made between paired jejunal biopsies collected using a Keyes biopsy punch and a standard scissor excisional technique. There were no differences in speed of collection, diagnostic value of specimens, complication rates, or sample quality. In this study, the Keyes skin punch was found to be safe, rapid, and diagnostic in all animals. Based on results of this study, the use of a Keyes punch instrument can be recommended as an alternative to other open intestinal biopsy methods.
authors.affiliation: Chesapeake Veterinary Referral Center, Annapolis, Maryland 21401, USA.
authors.forename: Matthew M
authors.initials: MM
authors.lastname: Keats
authors.forename: Robert
authors.initials: R
authors.lastname: Weeren
authors.forename: Paul
authors.initials: P
authors.lastname: Greenlee
authors.forename: Krista L
authors.initials: KL
authors.lastname: Evans
authors.forename: Anne C
authors.initials: AC
authors.lastname: Minihan
mesh_terms: D000818:Animals; D001706:Biopsy / Q000295:instrumentation / Q000379:methods / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology*; D004285:Dogs; D005260:Female; D007410:Intestinal Diseases / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D008297:Male; D011446:Prospective Studies; D012680:Sensitivity and Specificity