Exhaled breath condensate (EBC) collection in cats--description of a non-invasive technique to investigate airway disease.
Exhaled breath condensate has been collected in other species and used as a non-invasive method of evaluating airway disease by measurement of various markers in the fluid, including hydrogen peroxide, nitric oxide, leukotrienes and prostaglandins. We describe a novel technique for the collection of exhaled breath condensate from cats, which enabled collection of fluid and measurement of its hydrogen peroxide concentration. Further studies will be needed to establish the value of this technique in the investigation of feline respiratory disease.
Sparkes
Andrew H
AH
Centre for Small Animal Studies, The Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk, CB8 7UU, UK. andy.sparkes@aht.org.uk
Mardell
Eleanor J
EJ
Deaton
Chris
C
Kirschvink
Nathalie
N
Marlin
David
D
D000818:Animals; D015415:Biomarkers; D001944:Breath Tests / Q000379:methods*; D016022:Case-Control Studies; D002371:Cat Diseases / Q000175:diagnosis* / Q000378:metabolism; D002415:Cats; D005260:Female; D006861:Hydrogen Peroxide / Q000378:metabolism; D015289:Leukotrienes / Q000378:metabolism; D008171:Lung Diseases / Q000175:diagnosis / Q000662:veterinary*; D008297:Male; D009569:Nitric Oxide / Q000378:metabolism; D011237:Predictive Value of Tests; D011453:Prostaglandins / Q000378:metabolism
D015415:Biomarkers; D015289:Leukotrienes; D011453:Prostaglandins; D009569:Nitric Oxide; D006861:Hydrogen Peroxide