title: Data processing and exchange tools to facilitate chemical genetic screening processes.
abstract: Due to the development of chemical genomics, the screening of chemical libraries is used more and more by research laboratories to identify small molecule inhibitors or activators of cell functions. To facilitate the treatment and archiving of screening data, we developed a multiuser web application called Elisa Data Exchanger (EDE). The program is able to automatically identify which chemical compounds were tested. Several data exchange formats can be generated for visualization, printing, charting, or exporting to chemical analysis software. These data exchange functions allow for a comparison of results obtained from screening several targets in order to select the most specific compounds. EDE is freely available online at https://ibph.pharma.univ-montpl.fr/ede/ (login: evalede, password: loginede).
authors.affiliation: CNRS UMR 5160, Montpellier Cedex 5, France.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Leblanc
authors.forename: Adrien
authors.initials: A
authors.lastname: Coulet
authors.forename: Estelle
authors.initials: E
authors.lastname: André
authors.forename: Franck
authors.initials: F
authors.lastname: Molina
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Leonetti
mesh_terms: D020650:Combinatorial Chemistry Techniques / Q000379:methods; D003628:Database Management Systems; D016208:Databases, Factual; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods*; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet; D025941:Protein Interaction Mapping / Q000379:methods*; D012984:Software; D014584:User-Computer Interface