Synthesis and cellular uptake of a fluorescently labeled cyclic PNA-based compound.
A cyclic hexameric PNA-based compound labeled with fluorescein has been prepared following the liquid phase FPB strategy. Its cellular uptake, without and with electroporation, has been investigated by fluorescence microscopy.
Caldarelli
Sergio
S
Laboratoire de Chimie Bioorganique UMR-CNRS 6001, Université de Nice-Sophia Antipolis, Parc Valrose, 06108 Cédex 2, France.
Depecker
Geoffrey
G
Patino
Nadia
N
Di Giorgio
Audrey
A
Barouillet
Thibault
T
Doglio
Alain
A
Condom
Roger
R
D002462:Cell Membrane / Q000737:chemistry / Q000378:metabolism*; D019793:Fluorescein / Q000032:analysis / Q000378:metabolism*; D006367:HeLa Cells; D006801:Humans; D019169:Jurkat Cells; D009690:Nucleic Acid Conformation; D009757:Nylons / Q000032:analysis / Q000138:chemical synthesis* / Q000378:metabolism; D012313:RNA / Q000032:analysis / Q000138:chemical synthesis* / Q000378:metabolism
D009757:Nylons; D012313:RNA; D019793:Fluorescein