title: Hepatobiliary dysfunction as initial manifestation of disseminated cryptococcosis.
abstract: Disseminated cryptococcosis presenting as biliary obstruction is rare. We report a 35-year-old HIV-negative man who presented with clinical features suggestive of obstructive jaundice, and radiological features suggestive of Klatskin's tumor, but who ultimately was found to have cryptococcal involvement of the liver and biliary tract as part of disseminated cryptococcosis. The patient responded to antifungal therapy.
authors.affiliation: Department of General Surgery, Shri Sayajirao General Hospital and Medical College, Baroda-390 001, India. drankurkothari@hotmail.com
authors.forename: Ankur A
authors.initials: AA
authors.lastname: Kothari
authors.forename: Komal A
authors.initials: KA
authors.lastname: Kothari
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage; D002764:Cholecystitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D002779:Cholestasis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D003131:Combined Modality Therapy; D003453:Cryptococcosis / Q000175:diagnosis* / Q000188:drug therapy; D003937:Diagnosis, Differential; D004322:Drainage / Q000379:methods; D005500:Follow-Up Studies; D016469:Fungemia / Q000175:diagnosis* / Q000188:drug therapy; D018023:HIV Seronegativity; D006801:Humans; D007121:Immunocompetence; D008099:Liver / Q000382:microbiology / Q000473:pathology; D008111:Liver Function Tests; D008297:Male; D018570:Risk Assessment; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents