title: Sulfoacetate generated by Rhodopseudomonas palustris from taurine.
abstract: Genes thought to encode (a) the regulator of taurine catabolism under carbon-limiting or nitrogen-limiting conditions and (b) taurine dehydrogenase were found in the genome of Rhodopseudomonas palustris. The organism utilized taurine quantitatively as a sole source of nitrogen (but not of carbon) for aerobic and photoheterotrophic growth. No sulfate was released, and the C-sulfonate bond was recovered stoichiometrically as sulfoacetate, which was identified by mass spectrometry. An inducible sulfoacetaldehyde dehydrogenase was detected. R. palustris thus contains a pathway to generate a natural product that was previously believed to be formed solely from sulfoquinovose.
authors.affiliation: Fachbereich Biologie der Universität Konstanz, 78457 Konstanz, Germany.
authors.forename: Karin
authors.initials: K
authors.lastname: Denger
authors.forename: Sonja
authors.initials: S
authors.lastname: Weinitschke
authors.forename: Klaus
authors.initials: K
authors.lastname: Hollemeyer
authors.forename: Alasdair M
authors.initials: AM
authors.lastname: Cook
mesh_terms: D000079:Acetaldehyde / Q000031:analogs & derivatives* / Q000378:metabolism; D000085:Acetates / Q000032:analysis / Q000378:metabolism*; D000445:Aldehyde Oxidoreductases / Q000378:metabolism; D050728:Betaine-Aldehyde Dehydrogenase; D012241:Rhodopseudomonas / Q000378:metabolism*; D013431:Sulfates / Q000378:metabolism; D013654:Taurine / Q000378:metabolism*
chemical_list: D000085:Acetates; D013431:Sulfates; D013654:Taurine; C015517:sulfoacetaldehyde; D000445:Aldehyde Oxidoreductases; D050728:Betaine-Aldehyde Dehydrogenase; D000079:Acetaldehyde