A 2 hour versus the 3 hour 100 g glucose tolerance test for diagnosing gestational diabetes mellitus.
OBJECTIVE
To determine how the omission of the third hour glucose measurement of the 100 g oral glucose tolerance test (GTT) affects the diagnosis of gestational diabetes mellitus (GDM).


METHODS
Retrospective chart review of 876 women delivered in a tertiary care hospital in Israel during a three-year period, who underwent a 100 g 3 hour oral GTT following an abnormal 50 g glucose screen. GDM was diagnosed according to the "criterion standard" accepted in the Fourth International Workshop Conference on GDM. The results of the 100 g 3 hour oral GTT were then retrospectively re-evaluated by omission of the third hour plasma glucose measurement from the "criterion standard".


RESULTS
GDM was diagnosed in 28.4% of the study. patients, while the omission of the third hour glucose measurement resulted in a 26.4% diagnosis of GDM. The perinatal data of the 18-omitted cases suggests that their exclusion from the GDM group would not have altered substantially the perinatal outcome of the study cohort.


CONCLUSIONS
A 100 g 2 hour oral GTT is a simple and economic alternative to the 100 g 3 hour oral GTT.
Jakobi
Peter
P
Department of Obstetrics and Gynecology, Rambam Medical Center, Haifa, Israel. japeter@012.net.il
Solt
Ido
I
Weissman
Amir
A
D001786:Blood Glucose; D003920:Diabetes Mellitus / Q000097:blood / Q000175:diagnosis; D016640:Diabetes, Gestational / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology*; D005260:Female; D005947:Glucose / Q000008:administration & dosage; D005951:Glucose Tolerance Test / Q000379:methods*; D006801:Humans; D007557:Israel / Q000453:epidemiology; D008499:Medical Records; D011237:Predictive Value of Tests; D011247:Pregnancy; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013997:Time Factors
D001786:Blood Glucose; D005947:Glucose