Use of the n-butyl cyanoacrylate adhesive and the polyglactine thread suture for corneal rhaphy in rabbit (Oryctolagus cunicullus).
The aim of this study was to evaluate the cicatricial repair of perforating cornea in rabbits, by using the N-butyl cyanoacrylate adhesive compared to the 910-polyglactine thread suture through macroscopic and histological assays. Corneas from 18 adult rabbits were perforated and subsequently occluded with N-butyl cyanoacrylate synthetic adhesive (right cornea) or by separated single points using the 910-polyglactine thread (left cornea). The rabbits were divided into groups containing three animals per group. Examination after 7, 15, and 30 days post-operative showed that both the synthetic adhesive and the suture were efficient in the occlusion of the surgical wounds, thus stabilizing the intra-ocular content. The N-butyl cyanoacrylate adhesive was shown to be superior to the 910-polyglactine suture thread with regards to the evolution and the organization of the healing process.
Mota
Francisco Cláudio Dantas
FC
College of Veterinary Medicine, Federal University of Uberlandia, Minas Gerais, Brasil. dantasmota@yahoo.com.br
Eurides
Duvaldo
D
Freitas
Patricia Maria Coletto
PM
Beletti
Marcelo Emílio
ME
Goulart
Michelle Rodriques
MR
Cunha
Lívia Maria Ferreira
LM
da Silva
Luiz Antonio Franco
LA
Fioravanti
Maria Clorinda Soares
MC
D000818:Animals; D003315:Cornea / Q000601:surgery*; D065306:Corneal Injuries; D004659:Enbucrilate / Q000627:therapeutic use*; D005260:Female; D008297:Male; D011098:Polyglactin 910 / Q000627:therapeutic use; D011817:Rabbits / Q000601:surgery*; D013537:Sutures; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014945:Wound Healing
D014014:Tissue Adhesives; D011098:Polyglactin 910; D004659:Enbucrilate