Rhodium catalysed tandem conjugate addition-protonation: an enantioselective synthesis of 2-substituted succinic esters.
The rhodium catalysed addition of potassium trifluoro(organo)borates to dimethyl itaconate generates an intermediate complex which on protonation provides enantioenriched succinic esters.
Moss
Rebecca J
RJ
Department of Chemistry, University of Bath, Claverton Down, Bath, UK BA2 7AY.
Wadsworth
Kelly J
KJ
Chapman
Christopher J
CJ
Frost
Christopher G
CG