title: Drug resistance in nematodes of veterinary importance: a status report.
abstract: Reports of drug resistance have been made in every livestock host and to every anthelmintic class. In some regions of world, the extremely high prevalence of multi-drug resistance (MDR) in nematodes of sheep and goats threatens the viability of small-ruminant industries. Resistance in nematodes of horses and cattle has not yet reached the levels seen in small ruminants, but evidence suggests that the problems of resistance, including MDR worms, are also increasing in these hosts. There is an urgent need to develop both novel non-chemical approaches for parasite control and molecular assays capable of detecting resistant worms.
authors.affiliation: Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA. rkaplan@vet.uga.edu
authors.forename: Ray M
authors.initials: RM
authors.lastname: Kaplan
mesh_terms: D000818:Animals; D000829:Animals, Domestic / Q000469:parasitology*; D000969:Antinematodal Agents / Q000494:pharmacology* / Q000627:therapeutic use; D004351:Drug Resistance; D018432:Drug Resistance, Multiple; D006801:Humans; D009348:Nematoda / Q000187:drug effects* / Q000235:genetics; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary*; D021261:Parasitic Sensitivity Tests / Q000662:veterinary
chemical_list: D000969:Antinematodal Agents