Usefulness of the GenoType MTBC assay for differentiating species of the Mycobacterium tuberculosis complex in cultures obtained from clinical specimens.
A novel DNA strip assay, GenoType MTBC, was evaluated for differentiation of Mycobacterium tuberculosis complex species from 77 positive liquid cultures in clinical practice. Species identification (M. tuberculosis [71 strains], Mycobacterium bovis subsp. bovis [5 strains], and Mycobacterium africanum subtype I [1 strain]) results were identical to conventional results. The sensitivity was slightly higher for this test than for the AccuProbe assay.
Richter
Elvira
E
Forschungszentrum Borstel, National Reference Center for Mycobacteria, Parkallee 18, 23845 Borstel, Germany. erichter@fz-borstel.de
Weizenegger
Michael
M
Fahr
Anne-Marie
AM
Rüsch-Gerdes
Sabine
S
D000818:Animals; D015373:Bacterial Typing Techniques; D002417:Cattle; D015342:DNA Probes; D004269:DNA, Bacterial / Q000235:genetics; D005838:Genotype; D006801:Humans; D009163:Mycobacterium bovis / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D009169:Mycobacterium tuberculosis / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D014376:Tuberculosis / Q000382:microbiology
D015342:DNA Probes; D004269:DNA, Bacterial