Micropatterned carbohydrate displays by self-assembly of glycoconjugate polymers on hydrophobic templates on silicon.
We report a novel strategy for micropatterned carbohydrate displays on Si substrates. This method exploited the hydrophobic-hydrophilic microfabrication by photolithography of ODS-SAM on Si substrates and the subsequent selective self-assembly of glycoconjugate polymers onto the hydrophobic regions. Protein micropatterning by molecular recognition on the carbohydrate substrates was also successful.
Miura
Yoshiko
Y
Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, 464-8603, Japan. miuray@mol.nagoya-u.ac.jp
Sato
Hajime
H
Ikeda
Takayasu
T
Sugimura
Hiroyuki
H
Takai
Osamu
O
Kobayashi
Kazukiyo
K
D006001:Glycoconjugates / Q000032:analysis / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D011108:Polymers / Q000032:analysis / Q000737:chemistry*; D012825:Silicon / Q000032:analysis / Q000737:chemistry*
D006001:Glycoconjugates; D011108:Polymers; D012825:Silicon