The early story of coronary artery disease.
Angina pectoris was first adequately described and named in 1772. However, coronary artery disease, as the cause, was noted in 1779. The pathology and clinical features of myocardial infarction were only recognized in 1912. The distinction between angina and infarction was clarified in the 1920s. Nitrate therapy remained the sole treatment until modern medical and surgical developments which this review does not cover.
Besterman
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Department of Medicine, Faculty of Medical Sciences, The University of the West Indies, Kingston 7, Jamaica, West Indies.
D000787:Angina Pectoris / Q000209:etiology / Q000266:history* / Q000473:pathology; D001344:Autopsy; D003324:Coronary Artery Disease / Q000150:complications / Q000266:history* / Q000473:pathology; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans