title: MR-guided transgluteal biopsies with an open low-field system in patients with clinically suspected prostate cancer: technique and preliminary results.
abstract: The purpose of this study was to examine the feasibility and safety of MR-guided biopsies with a transgluteal approach in patients with uncertain or suspicious prostate lesions. Twenty-five patients with uncertain or suspicious focal prostate lesions detected by high-field MR imaging of the prostate gland using endorectal coil imaging were biopsied with a transgluteal approach in a low-field MRI system (0.2 T, Concerto, Siemens). The procedures were guided using T1-weighted FLASH sequences. The prostate gland was biopsied repeatedly with a coaxial technique through a 15-gauge pencil tip with a 16-gauge biopsy handy (median 3.8 samples per patient). Complications and biopsy findings were documented retrospectively. Using T1-weighted sequences biopsy procedures were performed successfully with MR guidance in all cases without any side effects or complications. The median intervention time was 11.3 min. Pathological findings revealed ten cases of hyperplasia or atrophy, three cases of prostatitis, ten cases of carcinoma and two cases of normal tissue. The clinical follow-up showed that in two patients prostate cancer was missed at MR-guided biopsy. Transgluteal MR-guided biopsy of the prostate gland is a safe and promising approach for histological clarification of uncertain or suspicious lesions.
authors.affiliation: Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Johann Wolfgang Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany. zangos@em.uni-frankfurt.de
authors.forename: Stephan
authors.initials: S
authors.lastname: Zangos
authors.forename: Katrin
authors.initials: K
authors.lastname: Eichler
authors.forename: Kerstin
authors.initials: K
authors.lastname: Engelmann
authors.forename: Mukhtiar
authors.initials: M
authors.lastname: Ahmed
authors.forename: Sebastian
authors.initials: S
authors.lastname: Dettmer
authors.forename: Christopher
authors.initials: C
authors.lastname: Herzog
authors.forename: Wasilios
authors.initials: W
authors.lastname: Pegios
authors.forename: A
authors.initials: A
authors.lastname: Wetter
authors.forename: Thomas
authors.initials: T
authors.lastname: Lehnert
authors.forename: Martin G
authors.initials: MG
authors.lastname: Mack
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Vogl
mesh_terms: D000368:Aged; D001707:Biopsy, Needle / Q000379:methods*; D002081:Buttocks; D005240:Feasibility Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000473:pathology*; D012449:Safety