title: Quantity determination of T- and B-leucocytes in peripheral blood in patients with candida induced subprosthetic stomatitis.
abstract: BACKGROUND
  The presence of pathological transformation of Candida species and especially of C. albicans is determined to a great degree by the status of humoral and especially of the cell-mediated immunity. The prosthetic stomatitis (Stomatitis subprothetica) and its development also depends on the immunological status of the organism.
  
  
  OBJECTIVE
  In the present study we have set as a purpose to define the quantity of B- and T-lymphocytes (T-early and T-late) in the peripheral blood in patients with subprosthetic stomatitis and isolated and proved C. albicans from the microbial prosthetic plate and the mucosa under the prosthesis.
  
  
  METHODS
  We defined the quantity of the early and late E-rosette-forming T-lymphocytes by the method of Bach (1973) and The B-lymphocytes with complement receptors by the method of Mendes et al (1974) in 69 patients with subprosthetic stomatitis and in 33 people with plate prostheses without stomatitis
  
  
  RESULTS
  In both of the studied groups an elevation of the early T-lymphocytes and lower values for the late E-rossette-forming T-lymphocytes compared to the normal values were found. The relative proportion of B-lymphocytes is insignificantly higher (p > 0.1) in the patients compared to the control group. The values of T- and B-lymphocytes vary in different directions and they must be interpreted individually.
authors.affiliation: Department of Therapeutic Dentistry, Faculty of Dentistry, Higher Medical Institute, Plovdiv, Bulgaria.
authors.forename: E V
authors.initials: EV
authors.lastname: Popova
authors.forename: S I
authors.initials: SI
authors.lastname: Dermendjieva
authors.forename: R P
authors.initials: RP
authors.lastname: Vangelova
mesh_terms: D000917:Antibody Formation; D001402:B-Lymphocytes / Q000276:immunology*; D002176:Candida albicans; D002177:Candidiasis / Q000097:blood / Q000150:complications* / Q000276:immunology; D017266:Dental Prosthesis / Q000009:adverse effects*; D006801:Humans; D007111:Immunity, Cellular; D018655:Lymphocyte Count; D008437:Maxilla; D013280:Stomatitis / Q000097:blood / Q000209:etiology* / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*