Surfing the actomyosin wave: polarization of the C. elegans zygote.
Many cell types rely on asymmetrically localized PAR proteins to become polarized. New evidence reveals that cortical flows powered by actomyosin contractions can mobilize PAR complexes to create distinct cortical domains.
Seydoux
Geraldine
G
Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
D000205:Actomyosin / Q000502:physiology*; D000818:Animals; D001692:Biological Transport; D019521:Body Patterning; D017173:Caenorhabditis elegans / Q000196:embryology*; D004330:Drosophila; D008870:Microtubules / Q000378:metabolism; D008954:Models, Biological; D034622:RNA Interference
D000205:Actomyosin