[Water-soluble chemical constituents of Swertia davidi Franch].
OBJECTIVE
To study the active constituents of Swertia davidi Franch.


METHODS
Column chromatographies on silica gel, Sephadex LH-20 and Diaion-201 et al. were used to isolate and purify the chemical components. Their structures were identified by UV, IR, MS, NMR and 2D-NMR.


RESULTS
These compounds were elucidated as 8-O-beta-D-glucopyranosyl-1, 3, 5-trihydroxyxanthone (I), 5-O-beta-D-glucopyranosyl-1, 8-dihydroxy-3-methoxyxanthone (II), 5-O-beta-D-glucopyranosyl-1, 3, 8-trihydroxyxanthone (III) and swertamarin (IV).


CONCLUSIONS
Compound III is a new xanthone glucoside. The other compounds were isolated from this plant for the first time.
Zeng
Guang-yao
GY
Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
Tan
Gui-shan
GS
Xu
Kang-ping
KP
Xu
Xiao-ping
XP
Li
Fu-shuang
FS
Tan
Jian-bing
JB
Hu
Gao-yun
GY
D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D029967:Swertia / Q000737:chemistry*; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification*
C493342:5-O-glucopyranosyl-1,3,8-trihydroxyxanthone; D005960:Glucosides; D044004:Xanthones; C056208:norswertianolin