A new reaction: lead(IV) acetate-mediated oxidative fragmentation of homoallylic alcohols.
Treatment of a homoallylic alcohol with lead(IV) acetate in refluxing benzene for 2 hours results in an oxidative cleavage to give a carbonyl compound and an allylic acetate with high yield.
Preite
Marcelo D
MD
Departamento de Química Orgánica, Facultad de Química, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Casilla 306, Correo-22, Santiago, Chile. mpreite@puc.cl
Cuellar
Mauricio A
MA