title: [A case report of idiopathic hypogonadotropic hypogonadism with particular reference to monitoring of prostate volume].
abstract: A 23-year-old man visited our hospital, complaining of a lack of secondary sexual characteristics. Based on both clinical and endocrinological examinations, he was diagnosed as suffering from idiopathic hypogonadotropic hypogonadism (IHH). With human chorionic gonadotropin (hCG)/human menopausal gonadotropin (hMG) replacement therapy, clinical symptoms and serum testosterone levels improved to normal ranges. Interestingly, prostate volume as measured by transrectal ultrasonography increased considerably from 3.6 ml before treatment to 20.2 ml after treatment. The monitoring of prostate volume might be a parameter useful for evaluating the treatment effect of hCG/hMG replacement therapy in IHH.
authors.affiliation: Department of Urology, Nagoya Urology Hospital.
authors.forename: Kifu
authors.initials: K
authors.lastname: Hirayama
authors.forename: Koichi
authors.initials: K
authors.lastname: Okada
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Kanemitsu
authors.forename: Munekado
authors.initials: M
authors.lastname: Kojima
authors.forename: Yosimasa
authors.initials: Y
authors.lastname: Hayase
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D006062:Gonadotropins / Q000097:blood*; D006801:Humans; D007006:Hypogonadism / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008297:Male; D008596:Menotropins / Q000008:administration & dosage*; D011467:Prostate / Q000000981:diagnostic imaging*; D013739:Testosterone / Q000097:blood; D014463:Ultrasonography
chemical_list: D006063:Chorionic Gonadotropin; D006062:Gonadotropins; D013739:Testosterone; D008596:Menotropins