title: Identification of photoproducts from imazosulfuron by HPLC.
abstract: Photolysis of imazosulfuron was studied in aqueous solution under UV light. The reaction followed a pseudo-first-order kinetic with significant correlation coefficient. The major photodegradation products of imazosulfuron after irradiation under UV light were separated and tentatively identified by HPLC-MS analysis as (4,6-dimethoxypyrimidine-2-yl)aminocarbonylsulfamic acid, 4,6-dimethoxy-2-ureidopyrimidine and 2,2'-dichloro-[3,3'] bi [imidazo[1,2-a] pyridinyl]. The results indicate that different reaction pathways are followed: (1) cleavage of the sulfonylurea bridge; (2) desulfonylation, which can proceed either by a carbon-sulfur cleavage or a nitrogen-sulfur cleavage. A mechanism for the formation of the photoproducts is proposed.
authors.affiliation: Dipartimento di Chimica Farmaceutica e Tossicologica, Università degli Studi di Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy. morrica@unina.it
authors.forename: Patrizia
authors.initials: P
authors.lastname: Morrica
authors.forename: Paola
authors.initials: P
authors.lastname: Fidente
authors.forename: Serenella
authors.initials: S
authors.lastname: Seccia
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D007700:Kinetics; D010777:Photochemistry; D011725:Pyridines / Q000737:chemistry*; D011743:Pyrimidines / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D011725:Pyridines; D011743:Pyrimidines; C433346:1-(2-chloroimidazo(1,2-a)pyridin-3-ylsulfonyl)-3-(4,6-dimethoxypyrimidin-2-yl)urea