[Peripheral hemodynamics in neurocirculatory dystonia].
OBJECTIVE
To assess the state of peripheral hemodynamics in patients with neurocirculatory dystonia and elucidate its relation to disease duration and clinical presentation.


METHODS
Laser doppler flowmetry was used for the study of microcirculation in 25 healthy subjects and 91 patients with neurocirculatory dystonia.


RESULTS
Most healthy subjects (73.7%) had normocirculatory type of microcirculation. Hyperemic type was most frequent (36.7%) in patients with mild neurocirculatory dystonia, while majority (57.4%) of patients with moderate severity and severe neurocirculatory dystonia had congestive-stasical type of microcirculation. Hyperkinetic syndrome predominated in patients with hyperemic type of microcirculation, while hyperventilatory, astenic and asteno-neurotic syndromes were characteristic for those with congestive-stasical type. Moreover patients with congestive-stasical type had longer disease duration.


CONCLUSIONS
Changes of microcirculation observed in patients with neurocirculatory dystonia evidence for the presence of relationship between clinical signs and disease duration. Patients with congestive-stasical type of microcirculation were characterized by unfavorable course and longer disease duration.
Makolkin
V I
VI
I. M. Sechenov Moscow Medical Academy; ul. Bolshaya Pirogovskaya 2/6, 119881 Moscow, Russia.
Strizhakov
L A
LA
D004421:Dystonia; D006439:Hemodynamics; D006801:Humans; D008833:Microcirculation; D009449:Neurocirculatory Asthenia; D013577:Syndrome