title: N-nitrosations of basic amino acid residues in polypeptide.
abstract: Changes in the electrophoretic pattern were noted in the products of polypeptides of identical basic amino acids preincubated with reactive or degraded PN, suggesting the occurrence of N-nitrosation of the epsilon-amino group of lysine, the guanido group of arginine and the imidazole group of histidine. Additionally, increase in the N-nitroso immunoreactivity of preincubated histones H2A and H2B was detected by Western blot analysis.
authors.affiliation: Division of Science and Mathematics, Bethune-Cookman College, Daytona Beach, Florida 32114, USA. kuow@cookman.edu
authors.forename: Wu-Nan
authors.initials: WN
authors.lastname: Kuo
authors.forename: Dynisha
authors.initials: D
authors.lastname: Ivy
authors.forename: Luvina
authors.initials: L
authors.lastname: Guruvadoo
authors.forename: Atavia
authors.initials: A
authors.lastname: White
authors.forename: Latia
authors.initials: L
authors.lastname: Graham
mesh_terms: D000818:Animals; D001120:Arginine / Q000737:chemistry; D015153:Blotting, Western; D004591:Electrophoresis, Polyacrylamide Gel; D006639:Histidine / Q000737:chemistry; D006657:Histones / Q000737:chemistry; D008239:Lysine / Q000737:chemistry; D009584:Nitrogen / Q000737:chemistry; D010455:Peptides / Q000737:chemistry*; D011107:Polylysine / Q000737:chemistry; D011485:Protein Binding; D051381:Rats; D014466:Ultraviolet Rays
chemical_list: D006657:Histones; D010455:Peptides; D011107:Polylysine; D006639:Histidine; D001120:Arginine; D008239:Lysine; D009584:Nitrogen