title: Primary cardiac fibrosarcoma in a dog.
abstract: A primary cardiac fibrosarcoma in the right atrium of a 6-year-old Chihuahua dog is described. At necropsy, there was a firm, whitish and spherical mass in the right atrium. Histopathologically, the mass had moderate cellularity composed of spindle-shaped cells with scattered multinucleated giant cells. The tumor cells were arranged in interwoven bundles and sheets in the collagenous stroma. No metastases were observed. Ultrastructurally, the tumor cells mainly consisted of fibroblasts. Multinucleated giant cells did not have any certain organelles that would indicate a higher order of differentiation. Primary cardiac sarcomas in dogs are extremely rare.
authors.affiliation: Laboratory of Veterinary Teaching Hospital, School of Veterinary Medicine, Azabu University, Kanagawa, Japan.
authors.forename: Hiroo
authors.initials: H
authors.lastname: Madarame
authors.forename: Kanako
authors.initials: K
authors.lastname: Sato
authors.forename: Kikumi
authors.initials: K
authors.lastname: Ogihara
authors.forename: Toru
authors.initials: T
authors.lastname: Ishibashi
authors.forename: Yoko
authors.initials: Y
authors.lastname: Fujii
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Wakao
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005347:Fibroblasts / Q000000981:diagnostic imaging; D005354:Fibrosarcoma / Q000473:pathology / Q000662:veterinary*; D006325:Heart Atria / Q000473:pathology*; D006338:Heart Neoplasms / Q000473:pathology / Q000662:veterinary*; D007150:Immunohistochemistry / Q000662:veterinary; D007564:Japan; D008854:Microscopy, Electron / Q000662:veterinary; D014463:Ultrasonography