title: [Necrosed field model of high intensity focused ultrasound for tumor treatment].
abstract: High intensity focused ultrasound (HIFU) has become a new developed micro-invasive surgical treatment of tumor, which is a hot topic in basic and applied research field. HIFU has shown its unique advantages including micro-invasion and curative effect during the treatment of several kinds of superficial tumor, e. g. mammary cancer. Based on the cellular thermo-necrotic theory, the expression of omega value was introduced to establish the mathematic model of the necrosed field formed in HIFU treatment progress. A non-interferential and self-focused system with multi-transducer was used to verify the theoretical model. Results of this study proved that the necrosed field mathematic model can simulate the actual heating progress. The model of this study may predict the practical value of the necrosed field as well as the time needed to take shape.
authors.affiliation: Department of Biomedical Engineering, Tianjin University, Tianjin 300072, China.
authors.forename: Dong
authors.initials: D
authors.lastname: Ming
authors.forename: Baikun
authors.initials: B
authors.lastname: Wan
authors.forename: Lixin
authors.initials: L
authors.lastname: Zhang
authors.forename: Yong
authors.initials: Y
authors.lastname: Hu
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology / Q000628:therapy; D006801:Humans; D008954:Models, Biological; D009336:Necrosis; D009369:Neoplasms / Q000473:pathology / Q000628:therapy*; D014464:Ultrasonic Therapy / Q000379:methods*; D036761:Ultrasound, High-Intensity Focused, Transrectal / Q000379:methods*