title: In vivo short-term Doppler hemodynamic profiles of 189 Carpentier-Edwards Perimount pericardial bioprosthetic valves in the mitral position.
abstract: We sought to determine the hemodynamic performance of the Carpentier-Edwards Perimount pericardial valve in the mitral position. We reviewed the Doppler echocardiographic data on 189 patients (110 women; 68 +/- 12 years of age) who were implanted with this valve (7.6 days +/- 13 postoperatively) at our institution between September 2000 and May 2002. The average ejection fraction was 47%. For all valves, the peak velocity was 1.9 +/- 0.3 m/s, peak gradient was 15 +/- 4.8 mm Hg, and mean gradient was 5.8 +/- 2 mm Hg. The pressure half-time was 93 +/- 24 milliseconds, with a calculated effective orifice area of 2.5 +/- 0.6 cm2. The average effective orifice area by continuity equation (83 valves) was 1.5 +/- 0.5 cm2. The mitral regurgitation was graded mild or less in 97.5% of all valves. This is the largest series establishing the favorable hemodynamic behavior of the different sizes of a new Perimount mitral valve, and the reported data could serve as a reference.
authors.affiliation: Cleveland Clinic Foundation, Ohio 44195, USA.
authors.forename: Sibyll
authors.initials: S
authors.lastname: Goetze
authors.forename: Johannes
authors.initials: J
authors.lastname: Brechtken
authors.forename: Deborah A
authors.initials: DA
authors.lastname: Agler
authors.forename: James D
authors.initials: JD
authors.lastname: Thomas
authors.forename: Joseph F
authors.initials: JF
authors.lastname: Sabik
authors.forename: Wael A
authors.initials: WA
authors.lastname: Jaber
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001705:Bioprosthesis; D003326:Coronary Circulation / Q000502:physiology*; D015150:Echocardiography, Doppler / Q000379:methods*; D005260:Female; D006350:Heart Valve Prosthesis; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging*; D013997:Time Factors