[Leukinferon-induced changes in cytochemical parameters of the wound exudate neutrophilic granulocyte nucleus and cytoplasm in patients with maxillofacial phlegmons].
Clinical and cytochemical study of the wound exudate neutrophilic granulocytes (NG) in patients with maxillofacial phlegmons treated traditionally and with leukinferon (immunomodulator) added to basic therapy demonstrated a positive clinical effect and pronounced stimulation of NG in the patients treated with leukinferon. The time course of cytochemical parameters of NG cytoplasm and chromatin activity was principally different in the two groups of patients. A new tissue index of NG was developed, giving an accurate integral picture of the total biological activity of the wound exudate NG.
Tsymbalov
O V
OV
Beliaev
D L
DL
Evglevskiĭ
A A
AA
Demchenko
V A
VA
D000276:Adjuvants, Immunologic / Q000494:pharmacology / Q000627:therapeutic use*; D000328:Adult; D002467:Cell Nucleus / Q000187:drug effects; D002481:Cellulitis / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D002843:Chromatin / Q000187:drug effects; D016207:Cytokines / Q000494:pharmacology / Q000627:therapeutic use*; D003593:Cytoplasm / Q000187:drug effects; D004338:Drug Combinations; D005122:Exudates and Transudates / Q000166:cytology / Q000187:drug effects / Q000276:immunology; D005145:Face; D006651:Histocytochemistry; D006801:Humans; D007370:Interferon Type I / Q000494:pharmacology / Q000627:therapeutic use*; D008437:Maxilla; D008875:Middle Aged; D009504:Neutrophils / Q000187:drug effects* / Q000648:ultrastructure; D013268:Stimulation, Chemical; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects
D000276:Adjuvants, Immunologic; D002843:Chromatin; D016207:Cytokines; D004338:Drug Combinations; D007370:Interferon Type I; C062252:leukinferon