title: An experimental study in X-ray spectroscopy of the zirconium (Ca-PSZ) - bone interface. Microanalytic evaluation of the osteogenetic response.
abstract: Ultrastructural difractometric and chemical evaluations of calcium partially stabilized zirconium (Ca-PSZ) implants were performed in an in vivo study on animals in order to evaluate its biological behaviour. The chemical-morphological investigations demonstrated the presence of an osteogenetic activity at the bone-biomaterial interface. The new-osteogenesis was preceded by the formation of a loose connective tissue around the implants. This mesenchymal-type tissue without a capsular organization, allowing modulation of the mechanical forces to which the implant is subject, could be considered a positive event in the osteogenetic process and not a sign of future failure of the implant. Finally, microanalytical investigations carried out on non-implanted and implanted Ca-PSZ tools suggested that the surface of this ceramic material does not undergo modification once it has been inserted in the biological environment (12 months).
authors.affiliation: Institute of Normal Human Morphology, Faculty of Medicine, Ancona, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Mattioli-Belmonte
authors.forename: P
authors.initials: P
authors.lastname: Mengucci
authors.forename: N
authors.initials: N
authors.lastname: Specchia
authors.forename: G
authors.initials: G
authors.lastname: Gobbi
authors.forename: S
authors.initials: S
authors.lastname: Dubini
authors.forename: L
authors.initials: L
authors.lastname: Simonelli
authors.forename: F
authors.initials: F
authors.lastname: Greco
authors.forename: G
authors.initials: G
authors.lastname: Majni
authors.forename: G
authors.initials: G
authors.lastname: Biagini
authors.forename: C
authors.initials: C
authors.lastname: Rizzoli