title: CT colonography and colonoscopy: assessment of patient preference in a 5-week follow-up study.
abstract: OBJECTIVE
  To prospectively evaluate short- and midterm patient preference of computed tomographic (CT) colonography relative to colonoscopy in patients at increased risk for colorectal cancer and to elucidate determinants of preference.
  
  
  METHODS
  Consecutive patients at increased risk for colorectal cancer underwent CT colonography prior to scheduled colonoscopy. Patient experience and preference were assessed both directly after the examinations and 5 weeks after the examinations. Differences in pain, embarrassment, discomfort, and preference were assessed with the Wilcoxon signed rank sum test or a binomial test. Potential determinants of preference were investigated with logistic regression analyses.
  
  
  RESULTS
  Data for 249 patients were included. Fewer patients experienced severe or extreme pain during CT colonography (seven [3%] of 245) than during colonoscopy (81 [34%] of 241) (P < .001). Directly after both examinations, 168 (71%) of 236 patients preferred CT colonography; 5 weeks later, 141 (61%) of 233 patients preferred CT colonography (P < .001). Initially, a painful colonoscopy examination (odds ratio, 0.17; 95% confidence interval [CI]: 0.08, 0.38) was a determinant of CT colonography preference. Similarly, a painful (odds ratio, 3.70; 95% CI: 1.54, 8.92) or an embarrassing (odds ratio, 4.46; 95% CI: 1.18, 16.88) CT colonography examination was a determinant of colonoscopy preference. After 5 weeks, the presence of polyps emerged as a determinant of colonoscopy preference (odds ratio, 1.94; 95% CI: 1.02, 3.70), while the role of experiences waned.
  
  
  CONCLUSIONS
  Patients preferred CT colonography to colonoscopy; however, this preference decreased in time, while outcome considerations gradually replaced temporary experiences of inconvenience.
authors.affiliation: Departments of Radiology, Social Medicine, and Gastroenterology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands.
authors.forename: Rogier E
authors.initials: RE
authors.lastname: van Gelder
authors.forename: Erwin
authors.initials: E
authors.lastname: Birnie
authors.forename: Jasper
authors.initials: J
authors.lastname: Florie
authors.forename: Michiel P
authors.initials: MP
authors.lastname: Schutter
authors.forename: Joep F
authors.initials: JF
authors.lastname: Bartelsman
authors.forename: Pleun
authors.initials: P
authors.lastname: Snel
authors.forename: Johan S
authors.initials: JS
authors.lastname: Laméris
authors.forename: Gouke J
authors.initials: GJ
authors.lastname: Bonsel
authors.forename: Jaap
authors.initials: J
authors.lastname: Stoker
mesh_terms: D000368:Aged; D023881:Colonography, Computed Tomographic / Q000009:adverse effects / Q000523:psychology; D003113:Colonoscopy / Q000523:psychology; D015179:Colorectal Neoplasms / Q000175:diagnosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology; D017060:Patient Satisfaction; D012044:Regression Analysis; D018709:Statistics, Nonparametric