title: Seasonal variation of Buerger's disease in Northern part of Thailand.
abstract: OBJECTIVE
  Buerger's disease is a common peripheral arterial occlusive disease in Asia, Middle East, and eastern European countries. This study was undertaken to investigate the seasonal variation in admission pattern of with patients Buerger's disease at our institution which is a referral hospital in the Northern Thailand.
  
  
  METHODS
  Patients with Buerger's disease admitted to Chiang Mai University Hospital between January 1987 and December 2002 were studied retrospectively. Data are reported as mean+/-SD. Statistical significance was analyzed by Chi-square test.
  
  
  RESULTS
  Eighty-four patients (82 men and two women) with Buerger's disease were evaluated on 121 admissions. Forty-five were newly diagnosed cases, who were admitted for initial treatment, and 39 were known cases who experienced worsening of the disease. Sixty-three admissions (52%) took place during winter (November to February), 44 admissions (34.6%) during the rainy season (June-October) and only 14 admissions (11.6%) occurred during the summer (March-May). There was a significant difference in the monthly admission rates during the three seasons (p<0.05).
  
  
  CONCLUSIONS
  Admission for Buerger's disease showed a significant seasonal variation, with a peak in the winter followed by the rainy and summer season, respectively. Further research is needed to confirm our findings and evaluate the underlying mechanisms.
authors.affiliation: Department of Surgery, Chiang Mai University Hospital, 50200 Chiang Mai, Thailand.
authors.forename: K
authors.initials: K
authors.lastname: Laohapensang
authors.forename: K
authors.initials: K
authors.lastname: Rerkasem
authors.forename: V
authors.initials: V
authors.lastname: Kattipattanapong
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010343:Patient Admission; D012307:Risk Factors; D012621:Seasons; D012907:Smoking / Q000009:adverse effects; D013785:Thailand / Q000453:epidemiology; D013919:Thromboangiitis Obliterans / Q000453:epidemiology* / Q000209:etiology / Q000628:therapy