Clinical perspective on postoperative ileus and the effect of opiates.
Postoperative ileus (POI) is a mandatory period of cessation of intestinal function, after abdominal surgery. Over the last decade research has continued into this field, and while we continue to learn about pathogenesis, few controlled data are available for management. The clinical manifestations of POI are reviewed. Management techniques are also reviewed, including the use of postoperative care plans with early ambulation and diet, the effects of epidural anaesthesia, benefits of laparoscopic approaches for intestinal resection, and potential avenues for prevention using novel medications.
Delaney
C P
CP
Department of Colorectal Surgery and Minimally Invasive Surgical Center, Cleveland Clinic Foundation, Cleveland, Ohio, USA. delanec@ccf.org
D000701:Analgesics, Opioid / Q000009:adverse effects*; D000818:Animals; D013505:Digestive System Surgical Procedures / Q000009:adverse effects; D006801:Humans; D045823:Ileus / Q000139:chemically induced / Q000188:drug therapy / Q000517:prevention & control*; D009292:Narcotic Antagonists / Q000627:therapeutic use; D011183:Postoperative Complications / Q000139:chemically induced / Q000188:drug therapy / Q000517:prevention & control*
D000701:Analgesics, Opioid; D009292:Narcotic Antagonists