Identification of a novel HLA-DRB1*12 allele (DRB1*1210) in the Korean population.
At least 11 HLA-DRB1*12 alleles have been identified to date. We report a new HLA-DRB1*12 allele, DRB1*1210, that was identified in the Korean population. This new allele differs from HLA-DRB1*120101 by a single nucleotide at position 40 (G-->A) in exon 1 that falls within codon--16 (GTT-->ATT). This change results in a single valine to isoleucine amino acid alteration.
Kim
E
E
National Genome Research Institute, National Institute of Health, Eunpyung-gu, Seoul, South Korea.
Lee
E J
EJ
Lim
Y H
YH
Lee
J Y
JY
Koh
I S
IS
Kimm
K
K
Ji
G E
GE
Kwack
K
K
D000483:Alleles; D019943:Amino Acid Substitution / Q000235:genetics*; D001483:Base Sequence; D005091:Exons / Q000235:genetics*; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D007723:Korea; D008969:Molecular Sequence Data
D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains