title: [Temporal lobe seizure recorded by magnetoencephalography: case report].
abstract: Ictal onset localization is a important factor in presurgical evaluation of epilepsy. This paper describes the localization of a seizure onset recorded by magnetoencephalography (MEG) from a 12-year-old male patient who suffered from complex partial drug-resistant seizures. MRI revealed a 20mm diameter lesion located in left hippocampus. Scalp EEG showed left temporal theta waves. Interictal MEG registrations detected isolated spike-wave activity posterior and inferior to the MRI lesion. Ictal MEG showed continuous spike-wave activity (2 Hz). Dipole localization sited seizure onset in the inferior left temporal gyrus, the same localization of the interictal MEG activity. This ictal activity spreads bilaterally to frontal areas. Intrasurgical electrocorticography recording confirmed interictal MEG results.
authors.affiliation: Centro de Magnetoencefalografía (MEG), Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain. cmeg@rect.ucm.es
authors.forename: Carlos
authors.initials: C
authors.lastname: Amo
authors.forename: Marta
authors.initials: M
authors.lastname: Santiuste
authors.forename: Fernando
authors.initials: F
authors.lastname: Maestú
authors.forename: Alberto
authors.initials: A
authors.lastname: Fernández
authors.forename: Renata
authors.initials: R
authors.lastname: Egatz
authors.forename: Mercedes
authors.initials: M
authors.lastname: González-Hidalgo
authors.forename: Cristóbal
authors.initials: C
authors.lastname: Saldaña
authors.forename: Antonio
authors.initials: A
authors.lastname: Sáiz
authors.forename: Tomás
authors.initials: T
authors.lastname: Ortiz
mesh_terms: D002648:Child; D004566:Electrodes; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D008297:Male; D011300:Preoperative Care; D012640:Seizures / Q000175:diagnosis*; D013702:Temporal Lobe