[Clinical research on radiofrequency ablation for hypersplenism].
OBJECTIVE
To study the security and curative effect of radiofrequency ablation (RFA) for hypersplenism due to portal hypertension in the near future.


METHODS
12 patients of the disease were treated with RFA. The blood count showed that WBC is (2.0 +/- 0.7) x 10(9)/L, PLT (25 +/- 10) x 10(9)/L, RBC (3.08 +/- 0.56) x 10(9)/L. In manners of systemic anaesthesia, through skin or in the operation or under the celioscopes the RFA needles are inserted the upper and middle parts of spleen in the instructing of US. Average time of RFA is (36.4 +/- 5.4) s.


RESULTS
After the RFA, 1 case develop hematoma under the envelope of liver, and 1 case developed skin burn; 6 patients appeared middle or little fluid in the left thorax, 2 of them were drawn through puncture. The volume of spleen and damaged part of spleen from RFA were determined by enhanced CT in the days of 10 after RFA, the percentage of damaged part of spleen from RFA is 49.1% (23.3% - 88.9%). In the days of 14 after RFA, RBC is (5.5 +/- 0.9) x 10(9)/L, PLT is (124 +/- 21.36) x 10(9)/L; In the days of 33 after RFA, RBC is (5.4 +/- 1.1) x 10(9)/L, PLT is (205 +/- 34) x 10(9)/L. The levels of WBC and PLT in the blood after RFA are significantly higher than those of levels of WBC and PLT before RFA (P < 0.01).


CONCLUSIONS
Radiofrequency ablation for Hypersplenism due to portal hypertension of hepatitis hepatocirrhosis is safety and credibility and has excellent curative effect in the near future.
Ma
Kuan-Sheng
KS
Institute of Hepatobiliary Surgery in Southwest Hospital, Third Military Medical University, The Southwest Hepatobiliary Surgery Hospital, Chongqing 400038, China.
Wu
Qiao
Q
Liu
Quan-Da
QD
Bie
Ping
P
Dong
Jia-Hong
JH
D000328:Adult; D017115:Catheter Ablation / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006971:Hypersplenism / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D006975:Hypertension, Portal / Q000150:complications*; D010535:Laparoscopy; D007813:Laparotomy; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D014463:Ultrasonography