Predicting and validating microRNA targets.
Given that microRNAs select their targets by nucleotide base-pairing, it follows that it should be possible to find microRNA targets computationally. There has been considerable progress, but assessing success and biological significance requires a move into the 'wet' lab.
Lai
Eric C
EC
545 Life Sciences Addition, Department of Molecular and Cell Biology and Howard Hughes Medical Institute, University of California at Berkeley, Berkeley, CA 94720-3200, USA. lai@fruitfly.org
D000818:Animals; D005823:Genetics; D035683:MicroRNAs / Q000235:genetics*; D011237:Predictive Value of Tests
D035683:MicroRNAs