Melanin synthesis may sensitize melanocytes to oxidative DNA damage by ultraviolet A radiation and protect melanocytes from direct DNA damage by ultraviolet B radiation.
Kvam
Egil
E
Dahle
Jostein
J
D000818:Animals; D004249:DNA Damage / Q000528:radiation effects*; D006801:Humans; D008543:Melanins / Q000096:biosynthesis*; D008544:Melanocytes / Q000378:metabolism*; D008545:Melanoma / Q000378:metabolism* / Q000473:pathology; D051379:Mice; D018384:Oxidative Stress / Q000528:radiation effects*; D014466:Ultraviolet Rays
D008543:Melanins