Repetitive transcranial magnetic stimulation does not potentiate antidepressant treatment.
In a double blind controlled study, rTMS results in a similar antidepressant effect to sham in combination with paroxetine. Both groups had the same delay in scale's scores improvement. rTMS seems not to be efficient as an add-on treatment to pharmacological medication in non-resistant major depression.
Poulet
E
E
EA 3092, Université Claude Bernard Lyon 1, 69677 Bron cedex, France.
Brunelin
J
J
Boeuve
C
C
Lerond
J
J
D'Amato
T
T
Dalery
J
J
Saoud
M
M
D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use*; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy*; D004311:Double-Blind Method; D006801:Humans; D017374:Paroxetine / Q000627:therapeutic use*; D010507:Periodicity; D012886:Skull; D011795:Surveys and Questionnaires; D050781:Transcranial Magnetic Stimulation / Q000295:instrumentation*
D018687:Antidepressive Agents, Second-Generation; D017374:Paroxetine