title: [Screening for diabetic retinopathy and optic disc topography with the "retinal thickness analyzer" (RTA)].
abstract: BACKGROUND
  The RTA features a fundus photography mode and optic disc topography. Those two new modes were investigated regarding their clinical use.
  
  
  METHODS
  First, the combination of wide-field photography with a retinal thickness map was assessed for tele-screening for diabetic retinopathy in 31 eyes. Second, normal values of the optic disc were collected on 30 non-glaucomatous probands in the non-mydriatic mode and compared to the results of the mydriatic mode, for which reproducibility was also investigated.
  
  
  RESULTS
  For diabetic retinopathy, the RTA yielded mean 93% sensitivity for proliferative diabetic retinopathy and 100% sensitivity for detecting diabetic macular edema compared to clinical examination at specificities ranging from 58 to 96%. Regarding the measurements of the optic disc, the normal values in mydriasis coincided with those in miosis in all but 4 of 12 parameters.
  
  
  CONCLUSIONS
  The RTA is suitable for application in tele-screening for diabetic retinopathy. The topography of the optic disc is highly reproducible and may be used for glaucoma diagnostics.
authors.affiliation: Augenklinik, Ludwig-Maximilians-Universität, München. aljoscha.neubauer@med.uni-muenchen.de
authors.forename: A S
authors.initials: AS
authors.lastname: Neubauer
authors.forename: C
authors.initials: C
authors.lastname: Chryssafis
authors.forename: M
authors.initials: M
authors.lastname: Thiel
authors.forename: S
authors.initials: S
authors.lastname: Priglinger
authors.forename: U
authors.initials: U
authors.lastname: Welge-Lüssen
authors.forename: A
authors.initials: A
authors.lastname: Kampik
mesh_terms: D003930:Diabetic Retinopathy / Q000175:diagnosis* / Q000473:pathology / Q000517:prevention & control / Q000601:surgery; D005451:Fluorescein Angiography / Q000295:instrumentation*; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation*; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D017075:Laser Coagulation; D009887:Ophthalmoscopy; D009898:Optic Disk / Q000473:pathology; D012016:Reference Values; D012160:Retina / Q000473:pathology*; D012680:Sensitivity and Specificity