title: A case of Budd-Chiari syndrome secondary to multiple thrombogenic conditions: a case report and review of literature.
abstract: This report describes a case of Budd-Chiari syndrome caused by latent polycythemia vera and factor V Leiden mutation. This syndrome usually occurs due to thrombosis of hepatic veins or membranous obstruction of inferior vena cava. The most common reasons for thrombosis are manifest polycythemia vera and the other prothrombotic conditions. Recently, latent polycythemia vera and factor V Leiden mutation have been reported in increasing frequency. In this report, we aimed to emphasize that all prothrombotic conditions must be evaluated while investigating the etiology of Budd-Chiari syndrome, including latent polycythemia vera and factor V Leiden mutation, and appropriate antithrombotic and surgical therapies must be performed without delay.
authors.affiliation: Department of Gastroenterohepatology, Haydarpaşa Numune Training and Research Hospital, Istanbul, Turkey. evrenabut@yahoo.com
authors.forename: Evren
authors.initials: E
authors.lastname: Abut
authors.forename: Hakan
authors.initials: H
authors.lastname: Güveli
authors.forename: Tülin
authors.initials: T
authors.lastname: Kendir
authors.forename: Cengiz
authors.initials: C
authors.lastname: Bölükbaş
authors.forename: Ali Tüzün
authors.initials: AT
authors.lastname: Ince
authors.forename: Ali Remzi
authors.initials: AR
authors.lastname: Dalay
authors.forename: Oya Ovünç
authors.initials: OO
authors.lastname: Kurdaş
mesh_terms: D000328:Adult; D006502:Budd-Chiari Syndrome / Q000000981:diagnostic imaging / Q000209:etiology* / Q000235:genetics; D018618:Echocardiography, Doppler, Color; D005165:Factor V / Q000235:genetics*; D017809:Fatal Outcome; D030342:Genetic Diseases, Inborn / Q000150:complications*; D006501:Hepatic Encephalopathy / Q000209:etiology; D006530:Hepatorenal Syndrome / Q000209:etiology; D006801:Humans; D008297:Male; D009154:Mutation; D011087:Polycythemia Vera / Q000150:complications*
chemical_list: C095381:factor V Leiden; D005165:Factor V