title: Bone viability determination in human cancellous bone from patients undergoing revision hip arthroplasty.
abstract: In December 2000, Sulzer Orthopedics Inc. announced the recall of specific lots of Inter-Op acetabular components as a result of an adverse tissue response to a contaminant on the porous surface of the component. This study was initiated to assess bone viability surrounding the primary and revision components. Twelve patients were placed on a double-tetracycline labeling protocol before revision surgery. Initial and final acetabular reamings were frozen-sectioned using cryostat technology. A mineral apposition rate, preoperative and postoperative radiographs, and Harris Hip Scores were evaluated. The tetracycline data showed that bone viability was not compromised at initial or final reaming levels in this series of patients. Significant improvement was observed in postoperative Harris Hip Scores when compared with preoperative Harris Hip Scores.
authors.affiliation: Department of Veterans Affairs, Salt Lake City Health Care System, Utah 84148, USA.
authors.forename: Roy D
authors.initials: RD
authors.lastname: Bloebaum
authors.forename: Ryan P
authors.initials: RP
authors.lastname: Ferguson
authors.forename: Christian M
authors.initials: CM
authors.lastname: Neff
authors.forename: Cornell
authors.initials: C
authors.lastname: Van Gorp
authors.forename: Douglas L
authors.initials: DL
authors.lastname: Woolley
authors.forename: Aaron A
authors.initials: AA
authors.lastname: Hofmann
mesh_terms: D000077:Acetabulum / Q000473:pathology*; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents; D019644:Arthroplasty, Replacement, Hip; D005260:Female; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010784:Photomicrography; D012086:Reoperation; D013752:Tetracycline
chemical_list: D000900:Anti-Bacterial Agents; D013752:Tetracycline