[Hemodynamic and rheological effects of polyetox in rats with crush syndrome].
Polyetox, a medicinal form of high-molecular-weight poly(ethylene oxide) (HMWPEO) improved peripheral blood supply, normalized the overall oxygen consumption, decreased erythrocyte aggregation, and reduced blood viscosity at low shear rate, and restored the antiturbulent properties (hydrodynamic index) of blood in the experiments on rats with crush syndrome. In rats with low resistance, polyetox increased the cardiac output.
Plotnikov
M B
MB
Chernyshova
G A
GA
Smol'iakova
V I
VI
Aliev
O I
OI
Sutormina
T G
TG
D000818:Animals; D001809:Blood Viscosity / Q000187:drug effects; D003444:Crush Syndrome / Q000097:blood / Q000503:physiopathology*; D004903:Erythrocyte Aggregation / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D018056:Hemorheology / Q000187:drug effects*; D008297:Male; D010101:Oxygen Consumption / Q000187:drug effects; D011092:Polyethylene Glycols / Q000494:pharmacology*; D051381:Rats; D012039:Regional Blood Flow / Q000187:drug effects
D011092:Polyethylene Glycols