title: Functional informatics: convergence and integration of automation and bioinformatics.
abstract: The biopharmaceutical industry is currently being presented with opportunities to improve research and business efficiency via automation and the integration of various systems. In the examples discussed, industrial high-throughput screening systems are integrated with functional tools and bioinformatics to facilitate target and biomarker identification and validation. These integrative functional approaches generate value-added opportunities by leveraging available automation and information technologies into new applications that are broadly applicable to different types of projects, and by improving the overall research and development and business efficiency via the integration of various systems.
authors.affiliation: Johnson & Johnson Pharmaceutical Research & Development, LLC, Welsh and McKean Roads, Spring House, PA 19477-0776, USA. silyin@prdus.jnj.com
authors.forename: Sergey E
authors.initials: SE
authors.lastname: Ilyin
authors.forename: Alejandro
authors.initials: A
authors.lastname: Bernal
authors.forename: Daniel
authors.initials: D
authors.lastname: Horowitz
authors.forename: Claudia K
authors.initials: CK
authors.lastname: Derian
authors.forename: Hong
authors.initials: H
authors.lastname: Xin
mesh_terms: D001331:Automation; D019295:Computational Biology; D023281:Genomics / Q000379:methods / Q000639:trends; D006801:Humans; D048088:Informatics; D013678:Technology, Pharmaceutical / Q000379:methods