Combined three-dimensional anisotropy contrast imaging and magnetoencephalography guidance to preserve visual function in a patient with an occipital lobe tumor.
OBJECTIVE
Three-dimensional anisotropy contrast (3-DAC) magnetic resonance imaging and magnetoencephalography (MEG) of visually evoked magnetic fields (VEFs) were used to accurately localize the optic radiation and primary visual cortex before surgery for an occipital tumor.


METHODS
A 26-year-old male presented with an occipital lobe tumor located intrinsically underneath the right calcarine fissure. 3-DAC imaging showed that the right optic radiation was located along the superior and lateral surfaces of the lesion. Mapping of the VEFs demonstrated that the primary visual cortex was located superior and lateral to the lesion. The lesion was totally resected via an infero-medial cortical incision using a frameless stereotactic system. Histopathology indicated a pilocytic astrocytoma. No visual deficit was found before or after surgery.


CONCLUSIONS
Combined 3-DAC imaging and MEG can provide essential information about the optic radiation and primary visual cortex for planning the surgical treatment of occipital lobe tumors.
Inoue
T
T
Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Fujimura
M
M
Kumabe
T
T
Nakasato
N
N
Higano
S
S
Tominaga
T
T
D000328:Adult; D016880:Anisotropy; D001254:Astrocytoma / Q000601:surgery*; D001932:Brain Neoplasms / Q000601:surgery*; D003287:Contrast Media / Q000008:administration & dosage; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D015225:Magnetoencephalography / Q000379:methods*; D009778:Occipital Lobe / Q000473:pathology* / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control*; D013238:Stereotaxic Techniques; D014786:Vision Disorders / Q000209:etiology* / Q000517:prevention & control*
D003287:Contrast Media