[Clinical differences observed in patients with dengue caused by different serotypes in the epidemic of 2001/2002, occurred in Rio de Janeiro].
The authors evaluated clinical and epidemiological differences among the serotypes of dengue in Rio de Janeiro's 2001-2002 outbreak of the disease. Out of 362 cases that had viral isolation samples, notified by the Information System for Notification Diseases (SINAN), from January/2001 to June/2002, 62 were caused by serotype 1,62 by serotype 2 and 238 by serotype 3. In comparison with serotype 2, an individual infected by serotype 3 had a 6.07 times higher chance (OR = 6.07; CI: 1.10-43.97) of presenting shock and a 3.55 times higher chance (OR = 3.55; CI: 1.28-9.97) of developing exanthema. When compared to serotype 1, serotype 3 had a 3.06 times higher chance (OR = 3.06; CI: 0.99-9.66) of causing abdominal pain and a 3.61 times higher chance of exanthema (OR = 3.61; CI: 1.16-11.51). It was found that individuals infected by serotype 3 of the virus presented signs indicating a more severe disease.
Passos
Maíla Naves Pereira
MN
Departamento de Medicina Preventiva, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro.
Santos
Luciana Maria Jabor Garcia
LM
Pereira
Marcelo Ricardo Reis
MR
Casali
Clarisse Guimarães
CG
Fortes
Bruno de Paula Menezes Drumond
Bde P
Ortiz Valencia
Luís Ivan
LI
Alexandre
Aline de Jesus
Ade J
Medronho
Roberto de Andrade
Rde A
D001938:Brazil / Q000453:epidemiology; D003715:Dengue / Q000453:epidemiology / Q000821:virology*; D003716:Dengue Virus / Q000145:classification*; D004196:Disease Outbreaks; D006801:Humans; D012703:Serotyping; D012720:Severity of Illness Index