Defective processing of unusually large von Willebrand factor multimers and thrombotic thrombocytopenic purpura.
Moake
J L
JL
Baylor College of Medicine and Rice University, Houston, TX, USA. jmoake@rice.edu
D051722:ADAM Proteins; D000071120:ADAMTS13 Protein; D000818:Animals; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008666:Metalloendopeptidases / Q000172:deficiency / Q000266:history / Q000502:physiology; D008954:Models, Biological; D046912:Multiprotein Complexes; D011499:Protein Processing, Post-Translational; D020836:Protein Structure, Quaternary; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000266:history; D011697:Purpura, Thrombotic Thrombocytopenic / Q000097:blood / Q000266:history*; D014481:United States; D014841:von Willebrand Factor / Q000737:chemistry / Q000266:history* / Q000502:physiology
D046912:Multiprotein Complexes; D014841:von Willebrand Factor; D051722:ADAM Proteins; D008666:Metalloendopeptidases; D000071120:ADAMTS13 Protein; C099604:ADAMTS13 protein, human