title: [Molecular epidemiological analysis of the spread of human immunodeficiency virus (HIV) infection in the Novosibirsk region].
abstract: The dynamics of the spread of individual subtypes of type 1 HIV (HIV-1), circulating in the Novosibirsk region during the epidemic rise of HIV infection was under study. The epidemic of HIV-1 in Novosibirsk has a pattern similar to that in Russia as a whole. At the initial stage of epidemics multiple sources of virus determine the heterogeneity of the isolated subtypes of HIV-1. Then the parenteral route of HIV transmission, connected with the intravenous use of narcotic drugs, becomes dominant. Recently the spread of HIV-1 from the group of intravenous drug users to other groups of the population has been observed. In the circulation of HIV-1 among drug users the leading role was shown to belong to subtype A, which ensures its rapid spread and dominating role in the epidemic process. Further spread of the HIV-1 epidemic is expected to proceed in parallel to the spread of viral hepatitis, sexually transmitted diseases and drug addiction. Thus, HIV-1, subtype A, may be assumed to be dominant in the Novosibirsk region in the nearest future.
authors.forename: N M
authors.initials: NM
authors.lastname: Gashnikova
authors.forename: E F
authors.initials: EF
authors.lastname: Bocharov
authors.forename: P A
authors.initials: PA
authors.lastname: Gladkiĭ
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Topchin
authors.forename: A G
authors.initials: AG
authors.lastname: Pokrovskiĭ
mesh_terms: D015658:HIV Infections / Q000453:epidemiology*; D015497:HIV-1 / Q000235:genetics*; D006801:Humans; D017720:Molecular Epidemiology; D009294:Narcotics / Q000008:administration & dosage; D012367:RNA, Viral / Q000235:genetics; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology; D015819:Substance Abuse, Intravenous / Q000453:epidemiology
chemical_list: D009294:Narcotics; D012367:RNA, Viral