title: Indolent herpetic whitlow of the toe in an elderly patient with diabetic neuropathy.
abstract: We report a case of indolent herpetic whitlow of the toe occurring in an elderly male patient with poorly controlled diabetes mellitus. In this case, the mechanism of transmission was not clear, although he was in a habit of taking a hot spring bath. This patient's symptoms were unusual for herpes simplex; he had no pain in the presence of diabetic neuropathy. The standard therapeutic dose of acyclovir was not effective in suppressing the lesions, and a higher dose was required to induce complete healing.
authors.affiliation: Department of Dermatology, Division of Internal Medicine, Tohoku University Graduate School of Medicine. ozawam@gonryo.med.tohoku.ac.jp
authors.forename: Maki
authors.initials: M
authors.lastname: Ozawa
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Ohtani
authors.forename: Hachiro
authors.initials: H
authors.lastname: Tagami
mesh_terms: D000212:Acyclovir / Q000008:administration & dosage / Q000627:therapeutic use; D000368:Aged; D000998:Antiviral Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002481:Cellulitis / Q000209:etiology; D017719:Diabetic Foot / Q000150:complications; D003929:Diabetic Neuropathies / Q000150:complications*; D005533:Foot Dermatoses / Q000175:diagnosis* / Q000209:etiology / Q000821:virology; D006561:Herpes Simplex / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000821:virology; D018259:Herpesvirus 1, Human / Q000302:isolation & purification; D006801:Humans; D006987:Hypesthesia / Q000209:etiology; D008297:Male; D014034:Toes / Q000821:virology
chemical_list: D000998:Antiviral Agents; D000212:Acyclovir