title: Endonasal endoscopic repair of cerebrospinal fluid rhinorrhea.
abstract: Cerebrospinal fluid (CSF) rhinorrhea implies a communication between the subarachnoid space and the upper respiratory tract. Trauma and postoperative defects are the more common causes of CSF rhinorrhea. The authors review their results with endoscopic repair of skull base defects associated with CSF rhinorrhea involving the paranasal sinuses. A total of 10 patients, 7 males and 3 females, were treated under endoscopic vision from 1997 to 2001. The causes of CSF rhinorrhea were traumatic (7), postoperative (2) and spontaneous (1). Four patients had the diagnosis and the site confirmed after intrathecal fluorescein-saline injection. The obliteration of the CSF leak was achieved with fat free, mucoperichondrial, or mucoperiostal free grafts taken from the middle or inferior turbinate and kept in place by fibrin glue. Primary closure was obtained in 10 patients and one patient developed a recurrence 14 months later. The repair of the CSF rhinorrhea by endonasal endoscopic surgery is safe, very effective and is a valid alternative to the cranial approach.
authors.affiliation: Department of Neurosurgery, Brazilian Air Force Hospital, Rio de Janeiro, Brazil. jlandeiro@aol.com
authors.forename: J A
authors.initials: JA
authors.lastname: Landeiro
authors.forename: B
authors.initials: B
authors.lastname: Lázaro
authors.forename: M H
authors.initials: MH
authors.lastname: Melo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002559:Cerebrospinal Fluid Rhinorrhea / Q000209:etiology / Q000601:surgery*; D004724:Endoscopy / Q000379:methods*; D005260:Female; D005402:Fistula / Q000601:surgery*; D019793:Fluorescein; D006801:Humans; D008297:Male; D008875:Middle Aged; D010256:Paranasal Sinuses / Q000601:surgery; D012189:Retrospective Studies; D019291:Skull Base / Q000293:injuries / Q000473:pathology* / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D019793:Fluorescein