title: A review of licensed viral vaccines, some of their safety concerns, and the advances in the development of investigational viral vaccines.
abstract: Viral vaccines could be considered among the most important medical achievements of the 20th century. They have prevented much suffering and saved many lives. Although some curative antiviral drugs exist, we desperately depend on efforts by academic, governmental and industrial scientists in the advancement of viral vaccines in the prevention and control of infectious diseases. In the next decade, we hope to see advancement in the development of current and investigational viral vaccines against childhood and adult infections. In this article, we will review the licensed viral vaccines, some of their safety concerns, and the advances in the development of investigational viral vaccines.
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA.
authors.forename: David B
authors.initials: DB
authors.lastname: Huang
authors.forename: Jashin J
authors.initials: JJ
authors.lastname: Wu
authors.forename: Stephen K
authors.initials: SK
authors.lastname: Tyring
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D015507:Drugs, Investigational / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D014765:Viral Vaccines / Q000009:adverse effects* / Q000276:immunology / Q000627:therapeutic use; D014777:Virus Diseases / Q000188:drug therapy / Q000276:immunology / Q000517:prevention & control
chemical_list: D015507:Drugs, Investigational; D014765:Viral Vaccines