title: Neurophysiologic findings in early acute inflammatory demyelinating polyradiculoneuropathy.
abstract: BACKGROUND
  Patients with early acute inflammatory demyelinating polyradiculoneuropathy (AIDP) may not meet the current neurophysiologic criteria.
  
  
  OBJECTIVE
  To document neurophysiologic findings in early AIDP.
  
  
  METHODS
  Clinical and neurophysiologic data from 38 AIDP patients, assessed within 10 days of symptom onset were reviewed.
  
  
  RESULTS
  In addition to absent H reflexes and abnormal F-wave responses in the acute stage of AIDP, abnormalities of blink reflexes, upper limb sensory responses abnormalities with spared sural responses, presence of distal CMAP dispersion, and A-waves were frequently observed. Established demyelinating neurophysiologic parameters were infrequently seen.
  
  
  CONCLUSIONS
  Abnormalities of H reflexes and F responses were most frequently noted in early AIDP. Additionally, distal temporal dispersion, prolonged or absent blink reflexes, and A-waves were often present in the acute stage of AIDP when classic diagnostic criteria of AIDP were not satisfied.
  
  
  CONCLUSIONS
  Neurophysiologic studies in early AIDP frequently reveal abnormalities that are not specific of primary demyelinating neuropathy.
authors.affiliation: Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
authors.forename: Steve
authors.initials: S
authors.lastname: Vucic
authors.forename: Kevin D
authors.initials: KD
authors.lastname: Cairns
authors.forename: Kristin R
authors.initials: KR
authors.lastname: Black
authors.forename: Peter Siao Tick
authors.initials: PS
authors.lastname: Chong
authors.forename: Didier
authors.initials: D
authors.lastname: Cros
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001767:Blinking / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D018450:Disease Progression; D004558:Electric Stimulation; D004576:Electromyography; D005071:Evoked Potentials / Q000502:physiology; D005260:Female; D020275:Guillain-Barre Syndrome / Q000503:physiopathology*; D006181:H-Reflex / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction; D009460:Neurologic Examination; D012189:Retrospective Studies