title: [Age-dependent changes of morphometric and histochemical characteristics of neurocytes in different ganglia of albino rats].
abstract: The aim of this study was to obtain the normative data on the age-dependent transformation of morphometric and histochemical characteristics of neurocytes in different ganglia in albino rats. Cell cross-sectional area, activities of cholinesterase (demonstrated with thioacetic acid method) monoamine oxidase (demonstrated with Glenner method) were measured in neurocytes of stellate, spinal, trigeminal and gastric ganglia in rats aged 2 to 360 days. Measurements were made with the help of "Bioscan" videoanalyzer. Informational analysis was used for the evaluation of the degree of maturation of neurocyte systems. General features, age- and organ-related peculiarities of morphometric and enzyme-histochemical characteristics were established for neurocytes of different ganglia, as well as a heterochronism of their definitive state attainment. The time of stabilization for neurocytes of stellate and I thoracic spinal ganglia was the age of 60 days, for those of trigeminal ganglion and intramural gastric ganglia -90 and 120 days, respectively. By this time, neurocyte systems turned from a determined state into a probabilistic-determined one, this transformation being considered as a population stabilization.
authors.forename: T A
authors.initials: TA
authors.lastname: Rumiantseva
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism; D000375:Aging / Q000473:pathology*; D000818:Animals; D005260:Female; D005724:Ganglia / Q000201:enzymology / Q000254:growth & development / Q000648:ultrastructure*; D008995:Monoamine Oxidase / Q000378:metabolism; D009475:Neurons, Afferent / Q000201:enzymology / Q000648:ultrastructure; D051381:Rats; D017208:Rats, Wistar
chemical_list: D008995:Monoamine Oxidase; D000110:Acetylcholinesterase