Catalytic enantioselective Michael addition of 1,3-dicarbonyl compounds to nitroalkenes catalyzed by well-defined chiral ru amido complexes.
Well-defined chiral Ru amido complexes promoted asymmetric Michael addition of 1,3-dicarbonyl compounds including malonates, beta-keto esters, and 1,3-diketones to nitroalkenes to give the corresponding adducts with excellent ees and in excellent yields.
Watanabe
Masahito
M
Department of Applied Chemistry, Graduate School of Science and Engineering, Tokyo Institute of Technology and Frontier Collaborative Research Center, O-okayama, Meguro-ku, Tokyo 152-8552, Japan.
Ikagawa
Ayako
A
Wang
Hui
H
Murata
Kunihiko
K
Ikariya
Takao
T