[The impact of diabetes mellitus on the results of coronary artery bypass grafting with respect to left ventricular function].
BACKGROUND
Diabetes mellitus is not only an independent risk factor for the development of arteriosclerosis, but also a risk factor for the surgical and interventional treatment of coronary artery disease (CAD).


METHODS
In 2003, a consecutive series of 2,142 patients underwent isolated coronary bypass grafting at the authors' institution, 567 of these suffering from diabetes mellitus.


RESULTS
An analysis of the diabetic and nondiabetic patients revealed a more pronounced risk profile, a significantly reduced left ventricular function and a significantly poorer quality of the coronary arteries in the diabetic group. Perioperative mortality in both groups was not different. The incidence of wound infections, renal failure and neurologic complications was much higher in diabetic patients.


CONCLUSIONS
From these findings it can be concluded that coronary artery bypass grafting in the current era is not associated with a higher perioperative mortality in diabetic patients despite their risk profile at baseline. The risk of wound infections and perioperative renal and neurologic complications is much higher in diabetic patients.
Kleikamp
Georg
G
Klinik für Thorax- und Kardiovaskularchirurgie, Herzzentrum Nordrhein-Westfalen, Universitätsklinik Ruhr-Universität Bochum, Bad Oeynhausen, Deutschland. gkleikamp@hdz-nrw.de
Maleszka
Ariane
A
Reiss
Nils
N
Körfer
Reiner
R
D000368:Aged; D015897:Comorbidity; D001026:Coronary Artery Bypass / Q000706:statistics & numerical data*; D003324:Coronary Artery Disease / Q000453:epidemiology* / Q000601:surgery*; D048909:Diabetes Complications / Q000453:epidemiology* / Q000601:surgery*; D005260:Female; D005858:Germany; D006801:Humans; D015994:Incidence; D008297:Male; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000453:epidemiology* / Q000517:prevention & control*