Allelic and haplotypic diversity at the rp1 rust resistance locus of maize.
The maize Rp1 rust resistance locus is a complex consisting of a family of closely related resistance genes. The number of Rp1 paralogs in different maize lines (haplotypes) varied from a single gene in some stocks of the inbred A188 to >50 genes in haplotypes carrying the Rp1-A and Rp1-H specificities. The sequences of paralogs in unrelated haplotypes differ, indicating that the genetic diversity of Rp1-related genes is extremely broad in maize. Two unrelated haplotypes with five or nine paralogs had identical resistance phenotypes (Rp1-D) encoded in genes that differed by three nucleotides resulting in a single amino acid substitution. Genes in some haplotypes are more similar to each other than to any of the genes in other haplotypes indicating that they are evolving in a concerted fashion.
Smith
Shavannor M
SM
Department of Plant Pathology, Kansas State University, Manhattan, Kansas 66506, USA.
Pryor
Anthony J
AJ
Hulbert
Scot H
SH
D001483:Base Sequence; D017931:DNA Primers; D014644:Genetic Variation; D007113:Immunity, Innate; D008969:Molecular Sequence Data; D010802:Phylogeny; D010935:Plant Diseases / Q000382:microbiology; D010940:Plant Proteins / Q000235:genetics*; D016133:Polymerase Chain Reaction; D016415:Sequence Alignment; D012689:Sequence Homology, Nucleic Acid; D003313:Zea mays / Q000145:classification / Q000235:genetics*
D017931:DNA Primers; D010940:Plant Proteins; C113020:ZmCip1 protein, Zea mays