[Effect of Compound Rhubarb Mixture on contraction of isolated small intestinal smooth muscle of rabbit].
OBJECTIVE
To investigate the effect of Compound Rhubarb Mixture on contraction of isolated small intestinal smooth muscle of rabbit.


METHODS
Serum containing Compound Rhubarb Mixture was prepared. The contraction curves of isolated small intestinal smooth muscle before and after administration of the serum were recorded by Medlab biological information collecting system.


RESULTS
The serum containing Compound Rhubarb Mixture amplified the contraction amplitude of isolated small intestinal smooth muscle of rabbit. The rate of change of contraction amplitude was elevated significantly after administration, while the frequency of contraction did not change obviously.


CONCLUSIONS
The serum containing Compound Rhubarb Mixture can enhance the contractive function of isolated small intestinal smooth muscle of rabbit.
Zhang
Hong-Quan
HQ
Medical and Pharmacological Institute, Yangzhou University, Yangzhou, Jiangsu Province 225001, China. hqzhang3000@eastday.com
Xu
Zheng-Xin
ZX
Wu
Yu-Qing
YQ
Zhou
Cheng-Hua
CH
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004365:Drugs, Chinese Herbal / Q000494:pharmacology; D005260:Female; D066298:In Vitro Techniques; D007421:Intestine, Small / Q000187:drug effects*; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects* / Q000502:physiology; D028321:Plant Preparations / Q000494:pharmacology*; D011817:Rabbits; D012250:Rheum
D004365:Drugs, Chinese Herbal; D028321:Plant Preparations