title: Proton magnetic resonance spectroscopy and magnetic resonance imaging findings in a patient with central nervous system paracoccidioidomycosis.
abstract: The authors describe a patient with brain paracoccidioidomycosis whose magnetic resonance image (MRI) showed multiple hypointense lesions on T2-weighted images with peripheral enhancement after gadolinium injection. Single-voxel proton magnetic resonance spectroscopy (1H-MRS) of one of the lesions showed 2 peaks at 0.9 and 1.32 ppm, corresponding to lipid signals, indicating intense necrosis. The other characteristic peaks of 1H-MRS were undifferentiated from baseline. These findings, although not specific, may help to differentiate fungal abscess from tumoral lesions and other types of abscess.
authors.affiliation: Department of Radiology, University of Campinas-UNICAMP, Campinas, SP, Brazil.
authors.forename: Andréia V
authors.initials: AV
authors.lastname: Faria
authors.forename: Guilherme C
authors.initials: GC
authors.lastname: Dabus
authors.forename: Verônica A
authors.initials: VA
authors.lastname: Zanardi
authors.forename: Fernando
authors.initials: F
authors.lastname: Cendes
mesh_terms: D000328:Adult; D002493:Central Nervous System Diseases / Q000175:diagnosis* / Q000382:microbiology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D010229:Paracoccidioidomycosis / Q000175:diagnosis*