title: Surgery alone in the curative treatment of localised oesophageal carcinoma.
abstract: OBJECTIVE
  To document the results of surgery alone in patients with localised oesophageal carcinoma.
  
  
  METHODS
  Between January 1982 and 2002, 179 consecutive patients who underwent curative oesophagectomy for stage 0, I or II oesophageal carcinoma, without neo-adjuvant treatment, were analysed retrospectively.
  
  
  RESULTS
  Postoperative mortality and morbidity rates were 2.8 and 30.7%, respectively. The overall actuarial survival rate at 5 years was 59%. No patients with more than four invaded lymph nodes survived 5 years. A lymph node ratio more than 0.2, more than four invaded lymph nodes and an advanced pTNM stage were predictors of poor prognosis.
  
  
  CONCLUSIONS
  Long-term survival after surgery alone for localised oesophageal carcinoma can be achieved in some 2/3rds of patients. These results should be considered before designing neo-adjuvant therapeutic regimen or embarking into exclusive treatment alternate to oesophagectomy.
authors.affiliation: Service de chirurgie digestive et générale Hôpital Claude Huriez, Centre Hospitalier Régional Universitaire, Place de Verdun, 59037 Lille cedex, France. c-mariette@chru-lille.fr
authors.forename: C
authors.initials: C
authors.lastname: Mariette
authors.forename: G
authors.initials: G
authors.lastname: Piessen
authors.forename: J M
authors.initials: JM
authors.lastname: Balon
authors.forename: I
authors.initials: I
authors.lastname: Van Seuningen
authors.forename: J P
authors.initials: JP
authors.lastname: Triboulet
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001707:Biopsy, Needle; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D015331:Cohort Studies; D004938:Esophageal Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D016629:Esophagectomy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011336:Probability; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D018570:Risk Assessment; D012737:Sex Factors; D018709:Statistics, Nonparametric; D016019:Survival Analysis; D016896:Treatment Outcome