[Role of iron ions in the production of hemolysin by toxigenic and nontoxigenic Vibrio cholerae of different serogroups].
The hemolytic activity of ctx- and ctx+ V. cholerae, serogroups eltor and O39, in a medium free of FeCl3 was studied. During the cultivation in this medium, the strains of both V. cholerae serogroups proved to be capable of lysing sheep red blood cells in the Graig test, irrespective of the presence of ctx genes. The cultivation of V. cholerae ctx+ strains of both serogroups under such conditions facilitated the production of hemolysin with the same spectrum of lytic activity as hemolysin produced by ctx- strains.
Men'shikova
E A
EA
Mironova
A V
AV
Podosinnikova
L S
LS
Mazrukho
A B
AB
Sokolenko
A V
AV
D000818:Animals; D000833:Animals, Suckling; D002460:Cell Line; D002712:Chlorides; D002772:Cholera Toxin / Q000235:genetics; D003470:Culture Media; D004912:Erythrocytes; D005290:Ferric Compounds; D006460:Hemolysin Proteins / Q000096:biosynthesis / Q000378:metabolism*; D006461:Hemolysis; D006801:Humans; D011817:Rabbits; D012756:Sheep; D014734:Vibrio cholerae / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity
D002712:Chlorides; D003470:Culture Media; D005290:Ferric Compounds; D006460:Hemolysin Proteins; D002772:Cholera Toxin; C024555:ferric chloride