Factor VII deficiency and its treatment in delivery with recombinant factor VII.
The authors present two cases of pregnant women with coagulation disorders--one with inherited deficiency of factor VII and the second with chronic hepatitis. Both cases were successfully treated with recombinant activated factor VII of coagulation (NovoSeven) in delivery. The advantages of using this product are discussed.
Pehlivanov
B
B
Department of Obstetrics and Gynecology, Medical University, 15-a Vassil Aprilov Str, Plovdiv 4000, Bulgaria. blago1956@yahoo.com
Milchev
N
N
Kroumov
G
G
D000328:Adult; D036861:Delivery, Obstetric; D005167:Factor VII / Q000627:therapeutic use*; D005168:Factor VII Deficiency / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D015942:Factor VIIa; D005260:Female; D006521:Hepatitis, Chronic / Q000097:blood / Q000150:complications; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000188:drug therapy*; D011994:Recombinant Proteins / Q000627:therapeutic use*; D016896:Treatment Outcome
D011994:Recombinant Proteins; D005167:Factor VII; C103587:recombinant FVIIa; D015942:Factor VIIa