title: Extensive use of polytetrafluoroethylene artificial grafts for prolapse of posterior mitral leaflet.
abstract: BACKGROUND
  There are an increasing number of reports concerning mitral valve repair by means of reconstruction of the chordae tendinae with expanded polytetrafluoroethylene (e-PTFE) sutures. However little information is available about extended application or results of this technique for extended prolapse of posterior mitral leaflets.
  
  
  METHODS
  Between March 1994 and December 2000, 22 patients with moderate-to-severe mitral regurgitation (MR) as the result of a prolapse of posterior leaflets (age range, 39-73 years) underwent mitral valve repair by means of reconstruction of artificial chordae with 4-CV e-PTFE sutures without leaflet resection. Either Kay's suture or ring annuloplasty was also performed to correct annular dilatation in all patients.
  
  
  RESULTS
  No operative death or late mortality was observed. Before discharge immediate postoperative echocardiography indicated less than moderate MR in 20 out of 22 patients. The follow-up was complete in all cases by clinical examination and serial echocardiograms and the median follow-up period was 87 months (range 24-108). There were two failures that required reoperation because of unsuccessful repair and worsening MR (elongation of the anchored side of the papillary muscle). When the reoperated patients were excluded from the follow-up data, the degree of MR, estimated by echocardiography that was performed at a recent follow-up period, was nonexistent in 6 patients, trivial in 10 patients, and mild in 4 patients. The systolic and diastolic dimensions of the left ventricle decreased significantly (p < 0.01).
  
  
  CONCLUSIONS
  Replacement of the artificial chordae was not complicated and seemed to preserve favorable relationships among leaflet tissues, chordae, and papillary muscles. We therefore suggest that the extensive use of PTFE artificial chordae seems to be a promising procedure regarding the repair of many kinds of mitral lesions causing MR.
authors.affiliation: Department of Cardiovascular Surgery, Faculty of Medicine, Kyushu University, Fukuoka, Japan. tomita@heart.med.kyushu-u.ac.jp
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Tomita
authors.forename: Hisataka
authors.initials: H
authors.lastname: Yasui
authors.forename: Toshiro
authors.initials: T
authors.lastname: Iwai
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nishida
authors.forename: Shigeki
authors.initials: S
authors.lastname: Morita
authors.forename: Munetaka
authors.initials: M
authors.lastname: Masuda
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Sano
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Nishimura
authors.forename: Hideki
authors.initials: H
authors.lastname: Tatewaki
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008422:Materials Testing; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology; D008945:Mitral Valve Prolapse / Q000150:complications / Q000601:surgery*; D011138:Polytetrafluoroethylene; D012086:Reoperation; D013536:Suture Techniques; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D011138:Polytetrafluoroethylene