title: The randomized trials of breast cancer screening: what have we learned?
abstract: Eight randomized controlled trials of mammography screening have been conducted to date. In addition to evaluating the efficacy of screening with an experimental design, the trials provided investigators with access to information about breast cancers much earlier in their development than had previously been available. The trials of mammographic screening provide conclusive evidence that the policy of offering screening is associated with a significant and substantial reduction in breast cancer mortality.
authors.affiliation: American Cancer Society, 1599 Clifton Road, NE, Atlanta, GA 30329, USA. robert.smith@cancer.org
authors.forename: Robert A
authors.initials: RA
authors.lastname: Smith
authors.forename: Stephen W
authors.initials: SW
authors.lastname: Duffy
authors.forename: Rhian
authors.initials: R
authors.lastname: Gabe
authors.forename: Laszlo
authors.initials: L
authors.lastname: Tabar
authors.forename: Amy M F
authors.initials: AM
authors.lastname: Yen
authors.forename: Tony H H
authors.initials: TH
authors.lastname: Chen
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000401:mortality; D005260:Female; D006801:Humans; D008327:Mammography; D016032:Randomized Controlled Trials as Topic; D012680:Sensitivity and Specificity; D015996:Survival Rate