[Ethanol-oxidizing enzymes of the adrenal glands in acute alcoholic intoxication].
Complex morphological-and-histological examinations of the adrenal glands were performed on actual forensic-medical samples in acute alcoholic intoxication (AAI), i.e. 107 death cases of men and women, aged 17 to 60, due to mechanical trauma, lethal ethanol intoxication and somatic complications of chronic alcoholism. A differentiated distribution of ethanol-oxidizing enzymes was defined, i.e. of alcohol-dehydrogenase and acetyl-dehydrogenase in the structural-and-functional zones of the adrenal cortex and medullary substance. A differential activity of enzymes was established that correlated with the level of exogenous alcoholemia. Sets of morphological signs related with examinations of the adrenal glands, which enabled a differential diagnosis of death causes in AAI, were specified.
Mamedov
V K
VK
Morozov
Iu E
IuE
Pigolkina
E Iu
EIu
D000293:Adolescent; D000311:Adrenal Glands / Q000201:enzymology* / Q000473:pathology*; D000328:Adult; D000426:Alcohol Dehydrogenase / Q000032:analysis*; D000435:Alcoholic Intoxication / Q000201:enzymology* / Q000401:mortality / Q000473:pathology*; D000444:Aldehyde Dehydrogenase / Q000032:analysis*; D000431:Ethanol / Q000378:metabolism; D005260:Female; D049429:Forensic Pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010084:Oxidation-Reduction
D000431:Ethanol; D000426:Alcohol Dehydrogenase; D000444:Aldehyde Dehydrogenase