[Inhibin B, predictive factor for testicular sperm recovery?].
Serum inhibin B is a glycoprotein of gonadal origin secreted by the sertoli cells and its secretion is regulated by interaction with the germ cells. Its role as a marker of spermatogenesis is clearly established. Therefore, its role as predictor for finding sperm by surgical testicular sperm retrieval in non-obstructive azoospermia was evaluated as in these patients sperm will only be recovered in half the cases. Our results together with a review of the reports published so far, show that although inhibin B is more accurate in predicting the result of sperm recovery, it cannot predict the outcome of a testicular sperm recovery in patients with non-obstructive azoospermia.
Vernaeve
V
V
Centre For Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free University (Vrije Universiteit Brussel), Laarbeeklaan 101, 1090 Bruxelles, Belgique. valerievernaeve@yahoo.fr
Brugnon
F
F
Tournaye
H
H
D006801:Humans; D007265:Inhibins / Q000097:blood*; D008297:Male; D009845:Oligospermia / Q000097:blood* / Q000473:pathology*; D012680:Sensitivity and Specificity; D013094:Spermatozoa / Q000473:pathology*; D013737:Testis / Q000473:pathology*; D020858:Tissue and Organ Harvesting
C422364:inhibin B; D007265:Inhibins
Inhibine B, facteur prédictif de la récupération de spermatozoïdes testiculaires?