Semicircular tumor of the iris and uveitis as unilocal manifestation of sarcoidosis.
OBJECTIVE
To describe an unusual manifestation of sarcoidosis as a large tumor of the iris and ciliary body without any other involvement of the body.


METHODS
We describe a 20-year-old female presenting with a granulomatous tumor of the right iris and ciliary body and concomitant uveitis.


RESULTS
Extensive ocular and systemic workup revealed the tumor to be a large solitary sarcoid granuloma. As systemic steroids were not able to control the activity of the uveitis and granuloma, only the initiation of immunosuppressive therapy with cyclosporine A achieved a lasting remission.


CONCLUSIONS
The possibility of an exclusively ocular sarcoidosis should always be kept in mind despite negative regular screening tests. In these cases, a biopsy should be considered and immunosuppressive agents like cyclosporine A should be evaluated in cases not responding to first-line treatment with systemic steroids.
Maca
S M
SM
Department of Ophthalmology, University of Vienna, Vienna, Austria.
Firbas
U
U
Hauff
W
W
Zettinig
G
G
Horvat
R
R
Barisani-Asenbauer
T
T
D000328:Adult; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006099:Granuloma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D006801:Humans; D007499:Iris Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008775:Methylprednisolone / Q000627:therapeutic use; D015864:Panuveitis / Q000175:diagnosis* / Q000188:drug therapy; D012507:Sarcoidosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D014463:Ultrasonography
D005938:Glucocorticoids; D008775:Methylprednisolone