SMAF-1 inhibits the APC/beta-catenin pathway and shows properties similar to those of the tumor suppressor protein APC.
Karaguni
Ioanna-Maria
IM
Max-Planck-Institut für Molekulare Physiologie, Abteilung Strukturelle Biologie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.
Gourzoulidou
Eleni
E
Carpintero
Mercedes
M
Langerak
Anette
A
Klein-Hitpass
Ludger
L
Möröy
Tarik
T
Winde
Günther
G
Waldmann
Herbert
H
Müller
Oliver
O
D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D002460:Cell Line; D049109:Cell Proliferation / Q000187:drug effects; D003598:Cytoskeletal Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000494:pharmacology*; D015870:Gene Expression / Q000187:drug effects; D017930:Genes, Reporter / Q000235:genetics; D051473:Maf Transcription Factors, Large; D051379:Mice; D009154:Mutation / Q000235:genetics; D015513:Oncogene Proteins / Q000494:pharmacology*; D015534:Trans-Activators / Q000037:antagonists & inhibitors / Q000378:metabolism* / Q000494:pharmacology*; D025521:Tumor Suppressor Proteins / Q000494:pharmacology*; D029961:Zebrafish Proteins / Q000494:pharmacology*; D051176:beta Catenin
C495267:CTNNB1 protein, mouse; D003598:Cytoskeletal Proteins; D004268:DNA-Binding Proteins; D051473:Maf Transcription Factors, Large; D015513:Oncogene Proteins; D015534:Trans-Activators; D025521:Tumor Suppressor Proteins; D029961:Zebrafish Proteins; D051176:beta Catenin; C425128:mafaa protein, zebrafish