Monitoring perspiration from palms of hypohidrosis patients with a stopped-flow conductometric mini-system.
BACKGROUND
Sensitive and real-time methods are required to characterize the symptoms and resolve the complicated pathology of hypohidrosis.


METHODS
We constructed a conductometric humidity sensor and a stopped-flow manifold with suitable dynamic range for monitoring impaired perspiration. The mini-sensor was coated with a water-absorbing polymer of poly-(2-acrylamido-2-methylpropane sulfonate).


RESULTS
Perspiration from palms of normal individuals and hypohidrosis patients were monitored and compared. Tangent slopes of the sensorograms were capable of discriminating hypohidrosis patients from normal individuals.


CONCLUSIONS
The conductometric min-sensor and the stopped-flow manifold were proven to be useful as a diagnostic tool for hypohidrosis.
Chang
Bin-Wha
BW
Institute of Biomedical Engineering, National Cheng-kung University, Tainan, Taiwan, ROC.
Yeh
Shoou-Jeng
SJ
Tsai
Ping-Ping
PP
Chang
Hsien-Chang
HC
D004553:Electric Conductivity; D006225:Hand; D006801:Humans; D006813:Humidity; D007007:Hypohidrosis / Q000175:diagnosis*; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods; D011108:Polymers; D012680:Sensitivity and Specificity; D013451:Sulfonic Acids; D013542:Sweat / Q000378:metabolism*; D013997:Time Factors
D011108:Polymers; D013451:Sulfonic Acids; C077118:poly(2-acrylamido-2-methyl-1-propanesulfonic acid)