title: Topical treatment for atopic dermatitis in the 21st century.
abstract: Atopic Dermatitis (AD) is a common cutaneous inflammatory disease. Recent estimates of prevalence in United States school children range from 10-20%. Topical treatment of AD is unsatisfactory. Now two new topical agents, tacrolimus and pimecrolimus, are revolutionizing the treatment of AD. Here we review AD as well as these breakthrough therapies.
authors.affiliation: Central Arkansas Veterans Healthcare System, USA.
authors.forename: Sandra Marchese
authors.initials: SM
authors.lastname: Johnson
authors.forename: Jay M
authors.initials: JM
authors.lastname: Kincannon
authors.forename: Danette L
authors.initials: DL
authors.lastname: Dudney
mesh_terms: D003876:Dermatitis, Atopic / Q000188:drug therapy*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016559:Tacrolimus / Q000031:analogs & derivatives* / Q000627:therapeutic use*
chemical_list: D003879:Dermatologic Agents; D007166:Immunosuppressive Agents; C117268:pimecrolimus; D016559:Tacrolimus