title: PhenomicDB: a multi-species genotype/phenotype database for comparative phenomics.
abstract: We have created PhenomicDB, a multi-species genotype/phenotype database by merging public genotype/phenotype data from a wide range of model organisms and Homo sapiens. Until now these data were available in distinct organism-specific databases (e.g. WormBase, OMIM, FlyBase and MGI). We compiled this wealth of data into a single integrated resource by coarse-grained semantic mapping of the phenotypic data fields, by including common gene indices (NCBI Gene), and by the use of associated orthology relationships. With its use-case-oriented user interface, PhenomicDB allows scientists to compare and browse known phenotypes for a given gene or a set of genes from different organisms simultaneously.
  
  
  BACKGROUND
  PhenomicDB has been implemented at Schering AG as described below. A PhenomicDB implementation differing in some technical details has been set up for the public at Metalife AG http://www.phenomicDB.de
  
  
  BACKGROUND
  database model, semantic mapping table.
authors.affiliation: Department of Bioinformatics, University of Applied Science Giessen, 35596 Giessen, Germany.
authors.forename: Abdullah
authors.initials: A
authors.lastname: Kahraman
authors.forename: Andrey
authors.initials: A
authors.lastname: Avramov
authors.forename: Lyubomir G
authors.initials: LG
authors.lastname: Nashev
authors.forename: Dimitar
authors.initials: D
authors.lastname: Popov
authors.forename: Rainer
authors.initials: R
authors.lastname: Ternes
authors.forename: Hans-Dieter
authors.initials: HD
authors.lastname: Pohlenz
authors.forename: Bertram
authors.initials: B
authors.lastname: Weiss
mesh_terms: D000818:Animals; D030541:Databases, Genetic; D004282:Documentation / Q000379:methods*; D020869:Gene Expression Profiling / Q000379:methods*; D023281:Genomics / Q000379:methods*; D005838:Genotype; D006801:Humans; D033181:Information Dissemination / Q000379:methods*; D016247:Information Storage and Retrieval / Q000379:methods*; D010641:Phenotype; D013045:Species Specificity