title: Biosynthetic pathway for the C45 polyprenol, solanesol, in tobacco.
abstract: Feeding experiments were independently performed with [1-13C]deoxy-D-xylulose triacetate and (RS)-[2-13C]mevalonolactone in the tobacco plant. The labeling pattern for solanesol was elucidated to reveal that the isoprene moiety of solanesol would be derived from deoxy-xylulose. The result strongly suggests that tobacco solanesol is biosynthesized via the 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway.
authors.affiliation: Department of Biotechnology, Graduate School of Engineering, Osaka University, Yamadaoka, Suita, Japan. fukusaki@bio.eng.osaka-u.ac.jp
authors.forename: Ei'ichiro
authors.initials: E
authors.lastname: Fukusaki
authors.forename: Shinya
authors.initials: S
authors.lastname: Takeno
authors.forename: Takeshi
authors.initials: T
authors.lastname: Bamba
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Okumoto
authors.forename: Hiroko
authors.initials: H
authors.lastname: Katto
authors.forename: Shin'ichiro
authors.initials: S
authors.lastname: Kajiyama
authors.forename: Akio
authors.initials: A
authors.lastname: Kobayashi
mesh_terms: D002070:Butadienes / Q000378:metabolism; D002250:Carbon Radioisotopes; D004896:Erythritol / Q000031:analogs & derivatives* / Q000378:metabolism; D045782:Hemiterpenes / Q000378:metabolism; D010420:Pentanes / Q000378:metabolism; D011849:Radioactive Tracers; D013403:Sugar Phosphates / Q000378:metabolism; D013729:Terpenes / Q000378:metabolism*; D014026:Nicotiana / Q000378:metabolism*; D014996:Xylulose / Q000031:analogs & derivatives* / Q000378:metabolism
chemical_list: C114232:2-C-methylerythritol 4-phosphate; D002070:Butadienes; D002250:Carbon Radioisotopes; D045782:Hemiterpenes; D010420:Pentanes; D011849:Radioactive Tracers; D013403:Sugar Phosphates; D013729:Terpenes; C005059:isoprene; D014996:Xylulose; C029724:1-deoxy-2-pentulose; C017719:solanesol; D004896:Erythritol