Parathyroid carcinoma: a multicenter review of clinicopathologic features and treatment outcomes.
We conducted a retrospective study of 13 patients with parathyroid carcinoma to assess their clinical characteristics and surgical outcomes. Study parameters included patient demographics, survival, treatment response, and recurrence. We found that all patients who had undergone local tumor excision developed a recurrence, compared with only 33% of those available for follow-up after en bloc tumor resection. Based on these findings, we recommend en bloc tumor resection as the initial treatment of choice for patients diagnosed with parathyroid carcinoma.
Wiseman
Sam M
SM
Department of Surgery, St. Paul's Hospital, University of British Columbia, Vancouver. smwiseman@providencehealth.bc.ca
Rigual
Nestor R
NR
Hicks
Wesley L
WL
Popat
Saurin R
SR
Lore
John M
JM
Douglas
Wade G
WG
Jacobson
Michael J
MJ
Tan
Dongfeng
D
Loree
Thom R
TR
D000328:Adult; D002277:Carcinoma / Q000473:pathology* / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010282:Parathyroid Neoplasms / Q000473:pathology* / Q000628:therapy*; D012189:Retrospective Studies; D016896:Treatment Outcome