title: A comparison of SepPak and high-performance liquid chromatography as techniques for measuring the radiochemical purity of 99mTc-MAG3.
abstract: OBJECTIVE
  To compare high-performance liquid chromatography and SepPak as techniques for measuring the radiochemical purity of 99mTc-MAG3.
  
  
  METHODS
  Samples of 99mTc-MAG3 (n = 20) with radiochemical purities in the range 43-98% were prepared and analysed by both techniques.
  
  
  RESULTS
  The correlation between the results from the two techniques was excellent (r = 1.00) and the differences between the results were not statistically significant (P > 0.05).
  
  
  CONCLUSIONS
  Both techniques are suitable for measuring the radiochemical purity of 99mTc-MAG3.
authors.affiliation: Department of Radiopharmacy, The Royal Infirmary of Edinburgh, Little France Crescent, UK. alistair.millar@luht.scot.nhs.uk
authors.forename: Alistair M
authors.initials: AM
authors.lastname: Millar
authors.forename: Stuart R
authors.initials: SR
authors.lastname: Hesslewood
mesh_terms: D005591:Chemical Fractionation / Q000379:methods*; D002847:Chromatography, Agarose / Q000379:methods*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D011785:Quality Assurance, Health Care / Q000379:methods*; D019275:Radiopharmaceuticals / Q000138:chemical synthesis / Q000302:isolation & purification; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D017263:Technetium Tc 99m Mertiatide / Q000737:chemistry* / Q000302:isolation & purification*
chemical_list: D019275:Radiopharmaceuticals; D017263:Technetium Tc 99m Mertiatide