title: [The chromosomal location of AD7C-NTP gene and the prediction of transmembrane domains of its deduced protein].
abstract: OBJECTIVE
  To characterize the chromosomal location of AD7C-NTP gene and predict the transmembrane domains and sub-cellular location of its deduced protein.
  
  
  METHODS
  The AD7C-NTP mRNA sequence was alignmented with human genomic DNA sequence by Blat server. The transmembrane domains and sub-cellular location of AD7C-NTP protein were predicted by using PHDhtm, TMHMM2.0, HMMTOP2.0, SMART and PSORT servers, etc.
  
  
  RESULTS
  The AD7C-NTP gene located in minus strand of 1p36.11, without intron. The AD7C-NTP protein was predicted to have 3 potential transmembrane domains and locate on peroxisome's membrane.
  
  
  CONCLUSIONS
  Bioinformatics analysis of the AD7C-NTP gene and its deduced protein provides valuable clues for further gene cloning and study of function.
authors.affiliation: Clinical Medical Research Institute, Urumqi General Hospital, Lanzhou Command of PLA, Urumqi 830000, China. guijunhao@163.net
authors.forename: Jun-hao
authors.initials: JH
authors.lastname: Gui
authors.forename: Jia-yun
authors.initials: JY
authors.lastname: Liu
authors.forename: Lin-tao
authors.initials: LT
authors.lastname: Jia
authors.forename: Dong-hui
authors.initials: DH
authors.lastname: Chou
authors.forename: Wu-zhong
authors.initials: WZ
authors.lastname: Yu
authors.forename: Jiang
authors.initials: J
authors.lastname: He
mesh_terms: D000544:Alzheimer Disease / Q000235:genetics*; D000595:Amino Acid Sequence; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D019295:Computational Biology / Q000379:methods; D018076:DNA, Complementary / Q000235:genetics; D006801:Humans; D009419:Nerve Tissue Proteins / Q000235:genetics* / Q000378:metabolism; D016571:Neural Networks, Computer; D020675:Peroxisomes / Q000235:genetics* / Q000378:metabolism; D011446:Prospective Studies; D012333:RNA, Messenger / Q000235:genetics; D016415:Sequence Alignment
chemical_list: C109804:AD7c-NTP; D018076:DNA, Complementary; D009419:Nerve Tissue Proteins; D012333:RNA, Messenger