title: Postbiopsy intramural hematoma of the duodenum in an adult with Noonan's syndrome.
abstract: Intramural duodenal hematoma is a rare complication of endoscopic biopsy. It is usually seen in children with growth failure and in patients with bleeding disorders or who are anticoagulated. It is frequently associated with acute pancreatitis. We present a case of an adult patient with Noonan's syndrome who developed postbiopsy intraduodenal hematoma. Abdominal ultrasound and computed tomography scan established the diagnosis. Conservative treatment was successful. According to a brief review of the literature, patients with Noonan's syndrome may develop hematoma after sampling of the duodenum because they present all the main predisposing factors. Additionally, pulmonic valve stenosis may be another predisposing factor, but this may warrant further investigation.
authors.affiliation: Department of Gastroenterology, Athens Naval and Veterans Hospital, Athens, Greece. spisgon@otenet.gr
authors.forename: Spiros N
authors.initials: SN
authors.lastname: Sgouros
authors.forename: George
authors.initials: G
authors.lastname: Karamanolis
authors.forename: Euthimia
authors.initials: E
authors.lastname: Papadopoulou
authors.forename: George
authors.initials: G
authors.lastname: Papageorgiou
authors.forename: Gerasimos
authors.initials: G
authors.lastname: Stefanides
authors.forename: Helias
authors.initials: H
authors.lastname: Nastos
authors.forename: Apostolos
authors.initials: A
authors.lastname: Mantides
mesh_terms: D000328:Adult; D001706:Biopsy / Q000009:adverse effects; D002908:Chronic Disease; D003967:Diarrhea / Q000150:complications / Q000209:etiology; D004378:Duodenal Diseases / Q000175:diagnosis / Q000209:etiology*; D004386:Duodenum / Q000473:pathology*; D006406:Hematoma / Q000209:etiology*; D006801:Humans; D008297:Male; D009634:Noonan Syndrome / Q000150:complications*