[Clinical study of shuizhitong capsule in treating senile vascular dementia].
OBJECTIVE
To observe the clinical therapeutic effect of Shuizhitong capsule (SZT) in treating senile vascular dementia (VD) and on changes of related physio-chemical criteria.


METHODS
Eighty-five patients with VD were randomly divided into the treated group (n = 51) and the control group (n = 34) in the ratio of 3:2, treated with SZT and Piracetam respectively. Before and after treatment, the Zhang's Dementia Scoring (HDS) and Function of Social Activity Questionnaire (FAQ) scoring, cerebral blood flow and hemorrheologic properties were determined.


RESULTS
SZT could significantly improve the patients' clinical symptoms, intracranial hemodynamic condition and the hyperviscosity, hypercoagulation and hyperaggregation status, lower the whole blood and plasma specific viscosity, raise the living standard of partial patients, with significant difference between before and after treatment (P < 0.05).


CONCLUSIONS
The therapeutic effect of SZT in treating senile VD is definite.
Fan
Xue-zhong
XZ
The Third Affiliated Hospital of Henan TCM College, Zhengzhou (450000). xifenli@yahoo.com
Yang
Bao-lin
BL
D000368:Aged; D001809:Blood Viscosity / Q000187:drug effects; D002214:Capsules; D002560:Cerebrovascular Circulation / Q000187:drug effects; D015140:Dementia, Vascular / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D018056:Hemorheology / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D018697:Nootropic Agents / Q000627:therapeutic use*; D008517:Phytotherapy
D002214:Capsules; D004365:Drugs, Chinese Herbal; D018697:Nootropic Agents