title: Application of directed orthometalation toward the synthesis of aryl siloxanes.
abstract: A selection of ortho-substituted aryl siloxanes have been prepared by directed orthometalation protocols. These siloxanes can be prepared in high yields and purity by use of a diverse selection of ortho-directing groups and electrophilic siloxane derivatives. The siloxanes are employed in palladium-catalyzed cross-coupling reactions with aryl bromides to generate unsymmetrical ortho-substituted biaryls in good to excellent yields.
authors.affiliation: Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, USA.
authors.forename: W Michael
authors.initials: WM
authors.lastname: Seganish
authors.forename: Philip
authors.initials: P
authors.lastname: DeShong
mesh_terms: D002384:Catalysis; D008956:Models, Chemical; D015394:Molecular Structure; D010165:Palladium; D012833:Siloxanes / Q000138:chemical synthesis*
chemical_list: D012833:Siloxanes; D010165:Palladium