The accuracy and optimal slice thickness of multislice helical computed tomography for right and left ventricular volume measurement.
BACKGROUND
Multislice helical computed tomography (MSCT) has been used to depict coronary anatomy noninvasively, and proved useful for evaluating ventricular function. The aim of our study was to assess the accuracy of ventricular volume as measured by MSCT.


METHODS
Fourteen human left ventricular (LV) and 15 right ventricular (RV) casts were scanned by MSCT. A series of LV and RV short-axis images were reconstructed later with slice thickness of 2.0 mm, 3.5 mm, 5.0 mm, 7.0 mm, and 10.0 mm. Ventricular volume was calculated by the multislice tomographic Simpson's method. True LV and RV cast volumes were determined by water displacement.


RESULTS
Both calculated LV and RV volumes correlated highly with the corresponding true volumes (all r >0.95, P <0.01). But with slice thickness from 2.0 mm to 10.0 mm, MSCT scanning overestimated the corresponding true volume by (3.21 +/- 5.95) ml to (12.58 +/- 8.56) ml for LV and (10.22 +/- 8.45) ml to (23.91 +/- 12.24) ml for RV (all P <0.01). There was a very high correlation between the overestimation and the selected slice thickness for both LV and RV volume measurements (r=0.998 and 0.996, P <0.01, respectively). However, when slice thickness was reduced to 5.0 mm, the overestimation for both LV and RV volume measurements became nonsignificant for slice thickness from 2.0 mm to 5.0 mm.


CONCLUSIONS
Both LV and RV volumes can be accurately estimated by MSCT. Thinner slice has more accurate calculated volume. However, 5.0 mm slice thickness is thin enough for an accurate measurement of LV or RV volume.
Cui
Wei
W
Department of Cardiology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, China. cuiwei@medmail.com.cn
Kondo
Takeshi
T
Anno
Hirofumi
H
Guo
Yu-yin
YY
Sato
Takahisa
T
Sarai
Masayoshi
M
Shinozaki
Hitoshi
H
Kakizawa
Satoshi
S
Sugiura
Kouji
K
Oshima
Keita
K
Katada
Kazuhiro
K
Hishida
Hitoshi
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D002306:Cardiac Volume; D002648:Child; D002675:Child, Preschool; D005260:Female; D006352:Heart Ventricles; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D036542:Tomography, Spiral Computed / Q000379:methods*