title: The effect of age and gender on glucuronidation and sulphation in rat liver: a study using paracetamol as a model substrate.
abstract: The effect of age and sex on glucuronidation and sulphation was studied in vitro in rat liver fractions, using paracetamol (acetaminophen) as substrate. Glucuronidation was more rapid in females; sulphation in males. Age was not a determinant of either metabolic pathway in either sex.
authors.affiliation: University of Wales College of Medicine, Cardiff Royal Infirmary (West Wing), Newport Road, Cardiff CF2 1SZ UK.
authors.forename: K
authors.initials: K
authors.lastname: Woodhouse
authors.forename: B
authors.initials: B
authors.lastname: Herd