title: Effect of organosoluble salts on the nanofibrous structure of electrospun poly(3-hydroxybutyrate-co-3-hydroxyvalerate).
abstract: Electrospinning of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) in chloroform was investigated to develop non-woven biodegradable nanofibrous structures for tissue engineering. Ultrafine PHBV fibers were obtained by electrospinning of 20 wt.% PHBV solution in chloroform and the resulting fiber diameters were in the range of 1.0-4.0 microm. When small amounts of benzyl trialkylammonium chlorides were added to the PHBV solution, the average diameter was decreased to 1.0 microm and the fibers were amounted in a straight shape. Conductivity of the PHBV solution was a major parameter affecting the morphology and diameter of the electrospun PHBV fibers. PHBV non-woven structures electrospun with salt exhibited a higher degradation rate than those prepared without salt probably due to the increase of surface area of PHBV fibers.
authors.affiliation: Department of Textile Engineering, Chungnam National University, Daejon 305 764, South Korea.
authors.forename: Jae Shin
authors.initials: JS
authors.lastname: Choi
authors.forename: Sung Won
authors.initials: SW
authors.lastname: Lee
authors.forename: Lim
authors.initials: L
authors.lastname: Jeong
authors.forename: Su-Hyun
authors.initials: SH
authors.lastname: Bae
authors.forename: Bum Chan
authors.initials: BC
authors.lastname: Min
authors.forename: Ji Ho
authors.initials: JH
authors.lastname: Youk
authors.forename: Won Ho
authors.initials: WH
authors.lastname: Park
mesh_terms: D000643:Ammonium Chloride / Q000737:chemistry; D001672:Biocompatible Materials; D002725:Chloroform; D004305:Dose-Response Relationship, Drug; D008855:Microscopy, Electron, Scanning; D008956:Models, Chemical; D036103:Nanotechnology; D011091:Polyesters / Q000737:chemistry* / Q000494:pharmacology*; D000644:Quaternary Ammonium Compounds / Q000737:chemistry; D012492:Salts / Q000737:chemistry; D013997:Time Factors; D000094122:Polyhydroxybutyrates
chemical_list: D000643:Ammonium Chloride; D001672:Biocompatible Materials; D002725:Chloroform; D011091:Polyesters; D000644:Quaternary Ammonium Compounds; D012492:Salts; C052620:poly(3-hydroxybutyrate)-co-(3-hydroxyvalerate); D000094122:Polyhydroxybutyrates