title: Exploring the limits of broadband excitation and inversion pulses.
abstract: The design of broadband excitation and inversion pulses with compensation of B(1)-field inhomogeneity is a long standing goal in high resolution NMR spectroscopy. Most optimization procedures used so far have been restricted to particular pulse families to keep the scale of the problem within manageable limits. This restriction is unnecessary using efficient numerical algorithms based on optimal control theory. A systematic study of rf-limited broadband excitation by optimized pulses and broadband inversion by optimized pulses with respect to bandwidth and B(1)-field is presented. Upper limits on minimum pulse lengths are set for different degrees of pulse performance.
authors.affiliation: Institut für Organische Chemie und Biochemie, Technische Universität München, Lichtenbergstrasse 4, D-85747 Garching, Germany.
authors.forename: Kyryl
authors.initials: K
authors.lastname: Kobzar
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Skinner
authors.forename: Navin
authors.initials: N
authors.lastname: Khaneja
authors.forename: Steffen J
authors.initials: SJ
authors.lastname: Glaser
authors.forename: Burkhard
authors.initials: B
authors.lastname: Luy
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D015233:Models, Statistical; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D015203:Reproducibility of Results