title: Assessing 24-hour blood glucose patterns in diabetic paitents treated by peritoneal dialysis.
abstract: The minute-to-minute effect on blood glucose levels of high-dextrose peritoneal dialysate is not known. We arranged for 7 patients with diabetes, treated by peritoneal dialysis (PD), to wear a continuous glucose monitoring system (CGMS: Medtronic MiniMed, Northridge, CA, U.S.A.). A sensor was inserted subcutaneously into the skin of the patient's abdomen or back to measure glucose in the interstitial fluid. Readings were recorded every 5 minutes for up to 72 hours. The portion of the day during which the patient's blood glucose levels were greater than 180 mg/dL (calculated as a percentage of time) was recorded. Most of the patients participating in the study had elevated levels of glycohemoglobin and hemoglobin A1c, and, for a large percentage of the day, showed blood glucose tracings well above the recommended standards of control. Representative CGMS tracings from patients with type 1 and type 2 diabetes are shown.
authors.affiliation: Department of Medicine, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio 44106, USA.
authors.forename: William D
authors.initials: WD
authors.lastname: Schwing
authors.forename: Penny
authors.initials: P
authors.lastname: Erhard
authors.forename: Lynda N
authors.initials: LN
authors.lastname: Newman
authors.forename: Megan M
authors.initials: MM
authors.lastname: Nodge
authors.forename: Barbara J
authors.initials: BJ
authors.lastname: Czechanski
authors.forename: Susan M
authors.initials: SM
authors.lastname: Orlin
authors.forename: Sarah M
authors.initials: SM
authors.lastname: Walden
authors.forename: Kim
authors.initials: K
authors.lastname: Behm
authors.forename: Carolyn P
authors.initials: CP
authors.lastname: Cacho
authors.forename: Lavina A
authors.initials: LA
authors.lastname: Negrea
authors.forename: David S
authors.initials: DS
authors.lastname: Siu
authors.forename: Elizabeth O
authors.initials: EO
authors.lastname: Kern
authors.forename: Miriam F
authors.initials: MF
authors.lastname: Weiss
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D003920:Diabetes Mellitus / Q000097:blood* / Q000188:drug therapy; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D018670:Monitoring, Ambulatory; D010530:Peritoneal Dialysis
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin