Validation of automatically measured monophasic action potential recordings.
This study devised an automatic monophasic action potential (MAP) measurement program, and compared the computer-measured MAP durations with those measured manually by two independent observers in order to facilitate the analysis of MAP data obtained during a clinical electrophysiology study. The results were compared at various cycle lengths and during pharmacologic or physiologic interventions. This program identified the onset, plateau, and baseline accurately using the MAP data. The automatically measured MAP durations at the 90% repolarization level (MAPd) strongly correlated with those measured manually (r = 0.99). The MAPd shortened in parallel as the pacing cycle length was progressively shortened from 800 to 600, 400 and 300 ms.
Lee
Jong-Min
JM
Department of Biomedical Engineering, Hanyang University, South Korea.
Nam
Gi-Byoung
GB
Rhee
Kyoungsuk
K
Choi
Kee-Joon
KJ
Kim
Sun I
SI
Kim
You-Ho
YH
D000200:Action Potentials; D004594:Electrophysiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010363:Pattern Recognition, Automated; D012815:Signal Processing, Computer-Assisted; D013617:Tachycardia, Supraventricular / Q000503:physiopathology