Living donor liver transplantation with left liver graft.
Small-for-size syndrome in LDLT is associated with graft exposure to excessive portal perfusion. Prevention of graft overperfusion in LDLT can be achieved through intraoperative modulation of portal graft inflow. We report a successful LDLT utilising the left lobe with a GV/SLV of only 20%. A 43 year-old patient underwent to LDLT at our institution. During the anhepatic phase a porto-systemic shunt utilizing an interposition vein graft anastomosed between the right portal branch and the right hepatic vein was performed. After graft reperfusion splenectomy was also performed. Portal vein pressure, portal vein flow and hepatic artery flow were recorded. A decrease of portal vein pressure and flow was achieved, and the shunt was left in place. The recipient post-operative course was characterized by good graft function. Small-for-size syndrome by graft overperfusion can be successfully prevented by utilizing inflow modulation of the transplanted graft. This strategy can permit the use of left lobe in adult-to-adult living donor liver transplantation.
Masetti
Michele
M
Liver and Multivisceral Transplant Center, University of Modena and Reggio Emilia, Modena, Italy. masetti.michele@unimo.it
Siniscalchi
Antonio
A
De Pietri
Lesley
L
Braglia
Vanessa
V
Benedetto
Fabrizio
F
Di Cautero
Nicola
N
Begliomini
Bruno
B
Romano
Antonio
A
Miller
Charles M
CM
Ramacciato
Giovanni
G
Pinna
Antonio D
AD
D000328:Adult; D005260:Female; D006801:Humans; D008099:Liver / Q000098:blood supply*; D016031:Liver Transplantation; D019520:Living Donors; D012038:Regeneration