Sarcoidosis manifesting as massive splenomegaly: a rare occurrence.
Sarcoidosis is a multisystemic granulomatous disease of unknown origin occurring worldwide and affecting people of all races and ages. This disease manifests most frequently with bilateral hilar lymphadenopathy, pulmonary infiltrates, and skin and ocular lesions. Granulomatous inflammation of the spleen is common in patients with sarcoidosis, but splenic enlargement is unusual and massive splenomegaly quite rare. Splenomegaly is usually homogeneous, but multiple low-attenuating nodular lesions are occasionally seen and easily mistaken for lymphoma, metastases, or infections such as tuberculosis. We describe an unusual case of sarcoidosis in a woman who presented with massive splenomegaly with extensive nodularity that cleared completely with corticosteroid therapy.
Mohan
Anant
A
Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.
Sood
Rita
R
Shariff
Nasir
N
Gulati
Manpreet Singh
MS
Gupta
Siddharth Datta
SD
Dutta
Amit Kumar
AK
D000328:Adult; D001706:Biopsy; D003287:Contrast Media; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D012507:Sarcoidosis / Q000000981:diagnostic imaging / Q000473:pathology*; D013163:Splenomegaly / Q000000981:diagnostic imaging / Q000209:etiology*; D014057:Tomography, X-Ray Computed
D003287:Contrast Media