[Use of MBDS as a tool for the detection of drug-related adverse events].
OBJECTIVE
To analyze drug-related adverse events (DRAE) as noted in hospital discharge reports, as well as their severity and drugs involved, and to assess potential avoidability.


METHODS
A retrospective study for the September-December 2002 period of time in which patients with discharge reports including an ICD-9-CM code E930-E949.9 were selected using the minimum basic data set (MBDS).


RESULTS
DRAEs were detected in 2.15% of all discharge reports, and 229 were retrospectively assessed. In all, 62.45% (n = 143) were DRAEs detected at the Emergency Department, and 37.55% (n = 86) were DRAEs detected during hospitalization. Of these, 57.20% are considered potentially avoidable. Drugs most commonly involved in the outpatient DRAE sample studied included: digoxin (24.47%, avoidable 97.14%) and NSAIDs-opioids (13.98%, avoidable 75%). Inpatient DRAEs included: anticoagulants (30.23%, avoidable 57.69%) and antimicrobials (17.44%, avoidable 26.67%).


CONCLUSIONS
The study revealed a high proportion of preventable DRAEs around a small number of drugs. Information to prescribing doctors and procedures for treatment follow-up using a unit dose drug dispensing system may be useful to reduce this.
Corral Baena
S
S
Servicio de Farmacia, Hospital Universitario Virgen Macarena, Sevilla. susana.corral@terra.es
Guerrero Aznar
M D
MD
Beltrán García
M
M
Salas Turrens
J
J
D000328:Adult; D016907:Adverse Drug Reaction Reporting Systems; D000368:Aged; D004358:Drug Therapy / Q000706:statistics & numerical data; D064420:Drug-Related Side Effects and Adverse Reactions; D004636:Emergency Service, Hospital; D005260:Female; D006760:Hospitalization; D006801:Humans; D038801:International Classification of Diseases; D008297:Male; D008499:Medical Records; D008508:Medication Errors / Q000706:statistics & numerical data; D008875:Middle Aged; D010351:Patient Discharge; D012189:Retrospective Studies; D017751:Safety Management
Utilización del CMBD como herramienta para la detección de acontecimientos adversos a medicamentos.