Inroads into base excision repair II. The discovery of DNA glycosylases. "An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues," Proc. Nat. Acad. Sci. USA, 1974.
The discovery of a DNA glycosylase that specifically removes uracil from DNA, opened the door for uncovering a large class of such enzymes that are fundamental to the process of base excision repair of DNA.
Friedberg
Errol C
EC
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Friedberg.errol@pathology.swmed.edu
Lindahl
Tomas
T
D045647:DNA Glycosylases / Q000266:history*; D004260:DNA Repair; D004269:DNA, Bacterial / Q000266:history; D004926:Escherichia coli / Q000201:enzymology*; D049673:History, 20th Century
D004269:DNA, Bacterial; D045647:DNA Glycosylases