Long-term outcomes in simultaneous pancreas-kidney transplantation: lessons relearned.
We analyzed 752 simultaneous pancreas kidney transplants performed at the University of Wisconsin from December 1985-February 2003. Patient survival rates at 5 and 10 years were 88% and 77%. The 5- and 10-year pancreas survival rates were 78% and 61% and the corresponding kidney survival rates were 80% and 59%. In this limited retrospective analysis of outcomes after simultaneous pancreas-kidney transplantation, the importance of donor selection is re-emphasized. Donor age and donor BMI significantly impact on graft and recipient survival. Furthermore, complications following SPK transplantation negatively impact on outcomes.
Di Carlo
Antonio
A
University of Wisconsin Hospital & Clinics, Department of Surgery, Division of Organ Transplantation, Madison, Wisconsin, USA.
Odorico
Jon S
JS
Leverson
Glen E
GE
Fernandez
Luis A
LA
Chin
L Thomas
LT
Becker
Yolanda T
YT
Knechtle
Stuart J
SJ
Pirsch
John D
JD
D'Alessandro
Anthony M
AM
Sollinger
Hans W
HW
D000293:Adolescent; D000328:Adult; D000375:Aging; D015992:Body Mass Index; D002648:Child; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation; D008875:Middle Aged; D016035:Pancreas Transplantation; D018579:Patient Selection; D016019:Survival Analysis; D013997:Time Factors; D014019:Tissue Donors; D016896:Treatment Outcome