title: Fatigue and depression in patients with lymphoma undergoing autologous peripheral blood stem cell transplantation.
abstract: OBJECTIVE
  To describe the patterns of depression and fatigue, including its dimensions, and the relationship between these two variables in patients with lymphoma undergoing autologous peripheral blood stem cell transplantation (PBSCT).
  
  
  METHODS
  Prospective, descriptive, correlational, repeated measures.
  
  
  METHODS
  Midwestern university National Cancer Institute-designated clinical cancer center.
  
  
  METHODS
  27 patients with lymphoma aged 19 to 71 undergoing autologous PBSCT.
  
  
  METHODS
  The revised Piper Fatigue Scale was used to measure fatigue and its dimensions. The Center for Epidemiologic Studies' Depression Scale was used to measure depression on selected days at baseline and during chemotherapy and recovery.
  
  
  METHODS
  Fatigue and its four dimensions (behavioral/severity, sensory, cognitive/mood, and affective meaning) and depression.
  
  
  RESULTS
  Total fatigue, fatigues four dimension scores, and depression scores changed significantly over time, with the highest scores at day + 7 after transplant. Total fatigue and the four dimension scores were highly and positively correlated with depression, with the highest correlation reported between the affective fatigue dimension and depression.
  
  
  CONCLUSIONS
  The findings support the importance of assessing fatigue and depression in patients undergoing autologous PBSCT at baseline, during chemotherapy, and throughout recovery.
  
  
  CONCLUSIONS
  Routine clinical assessment with close observation around day +7 after transplant and patient education about the patterns of fatigue and depression will help the healthcare team to intervene at the appropriate time and may help patients to better manage these symptoms.
authors.affiliation: Al-Zaytoonah University, Amman, Jordan. mmbanna@hotmail.com
authors.forename: Majeda Mohammad
authors.initials: MM
authors.lastname: El-Banna
authors.forename: Ann M
authors.initials: AM
authors.lastname: Berger
authors.forename: Lynne
authors.initials: L
authors.lastname: Farr
authors.forename: Martha J
authors.initials: MJ
authors.lastname: Foxall
authors.forename: Barbara
authors.initials: B
authors.lastname: Friesth
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Schreiner
mesh_terms: D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D003863:Depression / Q000209:etiology* / Q000451:nursing; D005221:Fatigue / Q000209:etiology* / Q000451:nursing; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy / Q000451:nursing / Q000523:psychology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D036102:Peripheral Blood Stem Cell Transplantation / Q000451:nursing / Q000523:psychology*; D011446:Prospective Studies; D012720:Severity of Illness Index; D014182:Transplantation, Autologous / Q000451:nursing / Q000523:psychology