title: Semicircular tumor of the iris and uveitis as unilocal manifestation of sarcoidosis.
abstract: OBJECTIVE
  To describe an unusual manifestation of sarcoidosis as a large tumor of the iris and ciliary body without any other involvement of the body.
  
  
  METHODS
  We describe a 20-year-old female presenting with a granulomatous tumor of the right iris and ciliary body and concomitant uveitis.
  
  
  RESULTS
  Extensive ocular and systemic workup revealed the tumor to be a large solitary sarcoid granuloma. As systemic steroids were not able to control the activity of the uveitis and granuloma, only the initiation of immunosuppressive therapy with cyclosporine A achieved a lasting remission.
  
  
  CONCLUSIONS
  The possibility of an exclusively ocular sarcoidosis should always be kept in mind despite negative regular screening tests. In these cases, a biopsy should be considered and immunosuppressive agents like cyclosporine A should be evaluated in cases not responding to first-line treatment with systemic steroids.
authors.affiliation: Department of Ophthalmology, University of Vienna, Vienna, Austria.
authors.forename: S M
authors.initials: SM
authors.lastname: Maca
authors.forename: U
authors.initials: U
authors.lastname: Firbas
authors.forename: W
authors.initials: W
authors.lastname: Hauff
authors.forename: G
authors.initials: G
authors.lastname: Zettinig
authors.forename: R
authors.initials: R
authors.lastname: Horvat
authors.forename: T
authors.initials: T
authors.lastname: Barisani-Asenbauer
mesh_terms: D000328:Adult; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006099:Granuloma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D006801:Humans; D007499:Iris Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008775:Methylprednisolone / Q000627:therapeutic use; D015864:Panuveitis / Q000175:diagnosis* / Q000188:drug therapy; D012507:Sarcoidosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D014463:Ultrasonography
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone