title: Refraction effects of diffraction-enhanced radiographic imaging: a new look at bone.
abstract: The objective of this study was to demonstrate the ability of a novel radiographic technology-diffraction-enhanced imaging-to detect contrast in bone tissue through absorption, refraction, and scatter rejection. Diffraction-enhanced imaging uses a synchrotron x-ray beam to produce images of high contrast by measuring the object's refraction and ultra-small angle scattering of x-rays in addition to the attenuation measured by conventional radiography. We present evidence that diffraction-enhanced imaging provides contrast enhancement at the edges of cortical and cancellous bone and a three-dimensional appearance of trabeculae.
authors.affiliation: Department of Anatomy and Cell Biology, Rush Medical College, Chicago, IL 60612, USA.
authors.forename: Carol
authors.initials: C
authors.lastname: Muehleman
authors.forename: Dale R
authors.initials: DR
authors.lastname: Sumner
authors.forename: Zhong
authors.initials: Z
authors.lastname: Zhong
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D007719:Knee Joint / Q000000981:diagnostic imaging; D011817:Rabbits; D011856:Radiographic Image Enhancement / Q000379:methods*