Connexins: gaps in our knowledge of vascular function.
Gap junctions are common features in the vasculature, long thought to provide a pathway for cell-cell signaling. Emerging understanding of the gap-junctional proteins (connexins) and new tools for their investigation now offer the opportunity to explore the vital role that the gap junctions may play in cardiovascular homeostasis and pathophysiology.
Figueroa
Xavier F
XF
Department of Molecular Physiology and Biological Physics, Cardiovascular Research Center, University of Virginia, Charlottesville, Virginia 22908, USA.
Isakson
Brant E
BE
Duling
Brian R
BR
D000818:Animals; D001808:Blood Vessels / Q000502:physiology*; D017630:Connexins / Q000502:physiology*; D017629:Gap Junctions / Q000502:physiology*; D006801:Humans
D017630:Connexins