PhenomicDB: a multi-species genotype/phenotype database for comparative phenomics.
We have created PhenomicDB, a multi-species genotype/phenotype database by merging public genotype/phenotype data from a wide range of model organisms and Homo sapiens. Until now these data were available in distinct organism-specific databases (e.g. WormBase, OMIM, FlyBase and MGI). We compiled this wealth of data into a single integrated resource by coarse-grained semantic mapping of the phenotypic data fields, by including common gene indices (NCBI Gene), and by the use of associated orthology relationships. With its use-case-oriented user interface, PhenomicDB allows scientists to compare and browse known phenotypes for a given gene or a set of genes from different organisms simultaneously.


BACKGROUND
PhenomicDB has been implemented at Schering AG as described below. A PhenomicDB implementation differing in some technical details has been set up for the public at Metalife AG http://www.phenomicDB.de


BACKGROUND
database model, semantic mapping table.
Kahraman
Abdullah
A
Department of Bioinformatics, University of Applied Science Giessen, 35596 Giessen, Germany.
Avramov
Andrey
A
Nashev
Lyubomir G
LG
Popov
Dimitar
D
Ternes
Rainer
R
Pohlenz
Hans-Dieter
HD
Weiss
Bertram
B
D000818:Animals; D030541:Databases, Genetic; D004282:Documentation / Q000379:methods*; D020869:Gene Expression Profiling / Q000379:methods*; D023281:Genomics / Q000379:methods*; D005838:Genotype; D006801:Humans; D033181:Information Dissemination / Q000379:methods*; D016247:Information Storage and Retrieval / Q000379:methods*; D010641:Phenotype; D013045:Species Specificity