[Infection with Gnathostoma spinigerum as a cause of eosinophilic oesophagitis].
METHODS
A 63-year-old man, who had travelled extensively in Asia and had lived in South Africa, presented with increasing dysphagia. Physical examination showed no abnormalities.


RESULTS
Upper gastrointestinal endoscopy showed a concentric oesophageal stenosis, 5 cm long, consisting of thickening of the wall without any sign of malignancy or mucocutaneous lesions. The histological examination of this lesion demonstrated infiltrations of eosinophilic cells. Serology was positive for Gnathostoma spinigerum.


METHODS
After treatment with albendazole 400 mg per day for 3 weeks the clinical, histological and serological symptoms resolved completely.


CONCLUSIONS
In case of any eosinophilia or local infiltrations of eosinophilic cells, parasitic disease have to be considered.
Müller-Stöver
I
I
Tropenmedizinische Ambulanz der Klinik für Gastroenterologie, Hepatologie und Infektologie, Universität Düsseldorf, Düsseldorf. Mueller-Stoever@med.uni-duesseldorf.de
Richter
J
J
Häussinger
D
D
D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D000909:Antibodies, Helminth / Q000097:blood; D015153:Blotting, Western; D003937:Diagnosis, Differential; D016145:Endoscopy, Digestive System; D004802:Eosinophilia / Q000469:parasitology*; D004940:Esophageal Stenosis / Q000469:parasitology*; D004941:Esophagitis / Q000469:parasitology*; D006039:Gnathostoma / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017205:Spirurida Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014195:Travel
D000871:Anthelmintics; D000909:Antibodies, Helminth; D015766:Albendazole
Infektion mit Gnathostoma spinigerum als Ursache einer eosinophilen Osophagitis.