title: Nucleation of calcium phosphate by surface-bound extracellular matrix.
abstract: The native extracellular matrix (ECM) laid down on silicon and titanium surfaces by osteoblast-like SAOS-2 cells was exposed by selective removal of cells. This type of material surface ECM-Si, ECM-Ti was shown to promote the nucleation of calcium phosphate from a simulated body fluid (SBF). Microscopic and spectroscopic results revealed the effect was associated with a collagen fiber-free extracellular matrix.
authors.affiliation: Forschungszentrum Rossendorf e.V., Institut für Ionenstrahlphysik und Materialforschung, Postfach 510119, 01314 Dresden, Deutschland. pham@fz-rossendorf.de
authors.forename: Minh Tan
authors.initials: MT
authors.lastname: Pham
authors.forename: Manfred Franz
authors.initials: MF
authors.lastname: Maitz
authors.forename: Helfried
authors.initials: H
authors.lastname: Reuther
authors.forename: Arndt
authors.initials: A
authors.lastname: Muecklich
authors.forename: Friedrich
authors.initials: F
authors.lastname: Prokert
authors.forename: Gerald
authors.initials: G
authors.lastname: Steiner
mesh_terms: D001826:Body Fluids / Q000737:chemistry; D002130:Calcium Phosphates / Q000737:chemistry* / Q000378:metabolism; D045744:Cell Line, Tumor; D020099:Coated Materials, Biocompatible / Q000737:chemistry* / Q000378:metabolism; D003094:Collagen / Q000378:metabolism; D005109:Extracellular Matrix / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D008422:Materials Testing; D018625:Microscopy, Atomic Force; D008854:Microscopy, Electron; D012825:Silicon / Q000737:chemistry / Q000378:metabolism; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry / Q000378:metabolism; D014961:X-Ray Diffraction
chemical_list: D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; D003094:Collagen; C020243:calcium phosphate; D014025:Titanium; D012825:Silicon