Structure of a quinobenzoxazine--G-quadruplex complex by REDOR NMR.
Rotational-echo double resonance solid-state (31)P[(19)F] and (13)C[(19)F] NMR spectra have been used to locate the binding of a fluoroquinobenzoxazine to a DNA G-quadruplex labeled by phosphorothioation and [methyl-(13)C]thymidine.
Mehta
Anil K
AK
Department of Chemistry, Washington University, St. Louis, Missouri 63130, USA.
Shayo
Yuda
Y
Vankayalapati
Hariprasad
H
Hurley
Laurence H
LH
Schaefer
Jacob
J
D001483:Base Sequence; D004247:DNA / Q000737:chemistry* / Q000235:genetics; D054856:G-Quadruplexes; D006147:Guanine / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D009690:Nucleic Acid Conformation; D010078:Oxazines / Q000737:chemistry*; D011804:Quinolines / Q000737:chemistry*
C492915:7-(3-aminopyrrol-1-yl)-11-carboxy-8-fluoro-10-oxoquino(2,3,4-ij)(1,4)benzoxazino(6,7-b)benzofuran; D010078:Oxazines; D011804:Quinolines; D006147:Guanine; D004247:DNA