Diterpenoid alkaloids from the roots of Delphinium scabriflorum.
Chemical investigation of the CHCl(3) extracts from the roots of Delphinium scabriflorum has resulted in the isolation of a new diterpenoid alkaloid, 13-(2-methylbutyryl)azitine (1), along with 11 known alkaloids, delbine (2), 14-deacetyl-14-isobutyrylajadine (3), methyllycaconitine (4), 14-deacetylnudicauline (5), delectinine (6), deltatsine (7), dictysine (8), geyerline (9), ajacine (10), lycoctonine (11), and delcosine (12). The structure of 1 was determined by spectroscopic data interpretation. Complete NMR data for alkaloids 2-8 are presented. Some earlier (13)C NMR assignments made for alkaloids 4-7 were revised.
Shrestha
Pradeep Man
PM
Natural Products Research Laboratory, Dr. Alfred Katz, Oberwilerstrasse 9, CH-4054 Basel, Switzerland.
Katz
Alfred
A
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D031882:Delphinium / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D008519:Medicine, Traditional; D015394:Molecular Structure; D009390:Nepal; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
D000470:Alkaloids; D004224:Diterpenes