Conversion of (2S)-arginine to (2S,3R)-capreomycidine by VioC and VioD from the viomycin biosynthetic pathway of Streptomyces sp. strain ATCC11861.
Ju
Jianhua
J
Division of Pharmaceutical Sciences, University of Wisconsin-Madison, Madison, WI 53705, USA.
Ozanick
Sarah G
SG
Shen
Ben
B
Thomas
Michael G
MG
D000904:Antibiotics, Antitubercular / Q000096:biosynthesis*; D001120:Arginine / Q000031:analogs & derivatives* / Q000378:metabolism*; D001426:Bacterial Proteins; D003500:Cyclization; D009682:Magnetic Resonance Spectroscopy; D019159:Nonheme Iron Proteins / Q000378:metabolism*; D010105:Oxygenases / Q000378:metabolism*; D013302:Streptomyces / Q000201:enzymology / Q000378:metabolism*; D000637:Transaminases / Q000378:metabolism*; D014756:Viomycin / Q000096:biosynthesis*
D000904:Antibiotics, Antitubercular; D001426:Bacterial Proteins; D019159:Nonheme Iron Proteins; C463580:capreomycidine; D001120:Arginine; D010105:Oxygenases; C497198:vioC protein, Chromobacterium violaceum; D000637:Transaminases; C497199:VioD aminotransferase; D014756:Viomycin