title: VioC is a non-heme iron, alpha-ketoglutarate-dependent oxygenase that catalyzes the formation of 3S-hydroxy-L-arginine during viomycin biosynthesis.
authors.affiliation: Department of Pharmaceutical Sciences, Oregon State University, Corvallis, Oregon 97331-3507, USA.
authors.forename: Xihou
authors.initials: X
authors.lastname: Yin
authors.forename: T Mark
authors.initials: TM
authors.lastname: Zabriskie
mesh_terms: D000904:Antibiotics, Antitubercular / Q000096:biosynthesis*; D001426:Bacterial Proteins; D002851:Chromatography, High Pressure Liquid; D003001:Cloning, Molecular; D003360:Cosmids / Q000235:genetics; D004269:DNA, Bacterial / Q000096:biosynthesis / Q000235:genetics; D004591:Electrophoresis, Polyacrylamide Gel; D006900:Hydroxylation; D009615:Nocardia / Q000201:enzymology / Q000378:metabolism; D019159:Nonheme Iron Proteins / Q000378:metabolism*; D010105:Oxygenases / Q000378:metabolism*; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000302:isolation & purification; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013302:Streptomyces / Q000201:enzymology / Q000378:metabolism; D014756:Viomycin / Q000096:biosynthesis*
chemical_list: D000904:Antibiotics, Antitubercular; D001426:Bacterial Proteins; D004269:DNA, Bacterial; D019159:Nonheme Iron Proteins; D011994:Recombinant Proteins; D010105:Oxygenases; C497198:vioC protein, Chromobacterium violaceum; D014756:Viomycin