Serum inhibin A, inhibin B, pro-alphaC, and activin A levels in women with idiopathic premature ovarian failure.
Serum inhibin A, inhibin B, pro-alphaC, and activin A levels in 30 women with idiopathic premature ovarian failure (POF), 30 postmenopausal women, and 30 age-matched fertile women were determined. Women with POF showed low levels of inhibin A and inhibin B, but not of activin A, whereas the levels of pro-alphaC were significantly higher than in postmenopausal women. Thus, the circulating level of pro-alphaC could be a marker for assessing residual ovarian function in women with POF.
Munz
Winfried
W
Department of Obstetrics and Gynecology, University of Saarland, Kirrberger Strasse, Homburg/Saar 66421, Germany. frwmun@uniklinik-saarland.de
Hammadeh
Mohamed Eid
ME
Seufert
Rudolf
R
Schaffrath
Michael
M
Schmidt
Werner
W
Pollow
Kunhard
K
D005260:Female; D006801:Humans; D007265:Inhibins / Q000097:blood*; D017698:Postmenopause; D016649:Primary Ovarian Insufficiency / Q000097:blood*; D011498:Protein Precursors / Q000097:blood*
D011498:Protein Precursors; C422362:inhibin A; C422364:inhibin B; C095971:inhibin-alpha subunit precursor; D007265:Inhibins