title: Abnormal behavior in children with temporal lobe epilepsy and ganglioglioma.
abstract: Temporal lobe epilepsy in childhood is characterized by great clinical, electroencephalographic, and etiological diversity. The prognosis after temporal lobe epilepsy surgery in childhood is usually good, with most patients achieving complete seizure control. However, in some children behavior deteriorates postoperatively. We report two girls (2 and 6 years of age) with refractory seizures due to temporal lobe ganglioglioma. They exhibited aggression and hyperactivity since the beginning of their epilepsy. In both patients, behavioral disturbances worsened postoperatively, despite complete seizure control. Patients and parents should be advised about possible behavioral disturbances after epilepsy surgery, especially in the presence of a temporal lobe developmental tumor, even when seizure control is achieved postoperatively.
authors.affiliation: Department of Neurology, FCM, UNICAMP Campinas, SP, Brazil.
authors.forename: Catarina A
authors.initials: CA
authors.lastname: Guimarães
authors.forename: Renata C
authors.initials: RC
authors.lastname: Franzon
authors.forename: Elisabete A P
authors.initials: EA
authors.lastname: Souza
authors.forename: Kátia M R S
authors.initials: KM
authors.lastname: Schmutzler
authors.forename: Maria Augusta
authors.initials: MA
authors.lastname: Montenegro
authors.forename: Luciano de S
authors.initials: Lde S
authors.lastname: Queiroz
authors.forename: Fernando
authors.initials: F
authors.lastname: Cendes
authors.forename: Marilisa M
authors.initials: MM
authors.lastname: Guerreiro
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000150:complications* / Q000523:psychology* / Q000601:surgery; D002648:Child; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000150:complications* / Q000523:psychology* / Q000601:surgery; D005260:Female; D018303:Ganglioglioma / Q000150:complications* / Q000523:psychology* / Q000601:surgery; D006220:Haloperidol / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D001523:Mental Disorders / Q000188:drug therapy / Q000209:etiology*; D019635:Neurosurgical Procedures; D011788:Quality of Life
chemical_list: D000927:Anticonvulsants; D014150:Antipsychotic Agents; D006220:Haloperidol