title: Long-term outcomes in simultaneous pancreas-kidney transplantation: lessons relearned.
abstract: We analyzed 752 simultaneous pancreas kidney transplants performed at the University of Wisconsin from December 1985-February 2003. Patient survival rates at 5 and 10 years were 88% and 77%. The 5- and 10-year pancreas survival rates were 78% and 61% and the corresponding kidney survival rates were 80% and 59%. In this limited retrospective analysis of outcomes after simultaneous pancreas-kidney transplantation, the importance of donor selection is re-emphasized. Donor age and donor BMI significantly impact on graft and recipient survival. Furthermore, complications following SPK transplantation negatively impact on outcomes.
authors.affiliation: University of Wisconsin Hospital & Clinics, Department of Surgery, Division of Organ Transplantation, Madison, Wisconsin, USA.
authors.forename: Antonio
authors.initials: A
authors.lastname: Di Carlo
authors.forename: Jon S
authors.initials: JS
authors.lastname: Odorico
authors.forename: Glen E
authors.initials: GE
authors.lastname: Leverson
authors.forename: Luis A
authors.initials: LA
authors.lastname: Fernandez
authors.forename: L Thomas
authors.initials: LT
authors.lastname: Chin
authors.forename: Yolanda T
authors.initials: YT
authors.lastname: Becker
authors.forename: Stuart J
authors.initials: SJ
authors.lastname: Knechtle
authors.forename: John D
authors.initials: JD
authors.lastname: Pirsch
authors.forename: Anthony M
authors.initials: AM
authors.lastname: D'Alessandro
authors.forename: Hans W
authors.initials: HW
authors.lastname: Sollinger
mesh_terms: D000293:Adolescent; D000328:Adult; D000375:Aging; D015992:Body Mass Index; D002648:Child; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation; D008875:Middle Aged; D016035:Pancreas Transplantation; D018579:Patient Selection; D016019:Survival Analysis; D013997:Time Factors; D014019:Tissue Donors; D016896:Treatment Outcome