Design of a robust Ru(salen) complex: aziridination with improved turnover number using N-arylsulfonyl azides as precursors.
A new robust fluorinated (OC)Ru(salen) complex was designed on the basis of an X-ray structure of its parent complex to show improved turnover numbers (up to 878) and enantioselectivities (up to 99%) in aziridination reactions using p-toluenesulfonyl (Ts) or p-nitrobenzenesulfonyl (Ns) azide as the nitrene precursor; the latter is synthetically advantageous since the Ns group is N-protecting and can be removed under mild conditions.
Omura
Kazufumi
K
Department of Chemistry, Faculty of Science, Graduate School, Kyushu University 33, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan.
Uchida
Tatsuya
T
Irie
Ryo
R
Katsuki
Tsutomu
T