title: Well-defined, organic nanoenvironments in water: the hydrophobic effect drives a capsular assembly.
abstract: The synthesis of a water-soluble, deep-cavity cavitand is reported. A blend of molecular curvature and amphiphilicity, this molecule has a hydrophobic concave surface and a hydrophilic convex surface. As a result, in aqueous solution and in the presence of a guest molecule, the host self-assembles to form a capsular assembly with an interior cavity large enough to entrap steroidal guests.
authors.affiliation: Department of Chemistry, University of New Orleans, New Orleans, LA 70148, USA.
authors.forename: Corinne L D
authors.initials: CL
authors.lastname: Gibb
authors.forename: Bruce C
authors.initials: BC
authors.lastname: Gibb