title: Inflammatory reaction following bovine pericardium graft augmentation for posterior vaginal wall defect repair.
abstract: Graft augmentation for repair of recurrent pelvic organ prolapse is commonly used in reconstructive pelvic surgery. The reported complications are mainly late onset. We report a case of early-onset inflammatory reaction following bovine pericardium graft augmentation for posterior vaginal wall defect repair. A 49-year-old presented with a recurrent and symptomatic posterior vaginal wall defect. She underwent an uneventful site-specific repair and bovine graft augmentation. Her early postoperative course was complicated by inflammatory response to the graft presenting as intense pelvic floor spasm and urinary retention. The condition was managed conservatively and resolved subsequently. One year later, the patient continues to be asymptomatic. Transient intense pelvic floor spasm and urinary retention can be the result of inflammatory reaction following graft augmentation with bovine pericardium for posterior vaginal wall defect repair.
authors.affiliation: Department of Obstetrics and Gynecology and Women's Health, Division of Female Pelvic Medicine and Reconstructive Surgery, Albert Einstein College of Medicine/Montefiore Medical Center Bronx, NY 10467, USA. glazarou@montefiore.org
authors.forename: George
authors.initials: G
authors.lastname: Lazarou
authors.forename: Kenneth
authors.initials: K
authors.lastname: Powers
authors.forename: Carlos
authors.initials: C
authors.lastname: Pena
authors.forename: Lance
authors.initials: L
authors.lastname: Bruck
authors.forename: Magdy S
authors.initials: MS
authors.lastname: Mikhail
mesh_terms: D000818:Animals; D002417:Cattle; D005260:Female; D006801:Humans; D007249:Inflammation / Q000209:etiology*; D008875:Middle Aged; D010496:Pericardium / Q000637:transplantation*; D019651:Plastic Surgery Procedures / Q000379:methods; D014183:Transplantation, Heterologous / Q000009:adverse effects* / Q000276:immunology; D014596:Uterine Prolapse / Q000601:surgery*; D014621:Vagina / Q000473:pathology / Q000601:surgery*