title: Composition and antimicrobial activities of volatile components of Lippia javanica.
abstract: The volatile oil of Lippia javanica was prepared by hydrodistillation of leaves, flowers and stems, and characterized by GC-MS. The major component was 3-methyl-6-(1-methylethylidene)-cyclohex-2-en-1-one. The oil was tested for antimicrobial activity on cultures of Escherichia coli, Bacillus subtilis and Staphylococcus aureus, and found to inhibit E. coli and S. aureus at 1% dilution. The oil was also active against Plasmodium falciparum in micromolar concentrations.
authors.affiliation: Department of Chemistry, University of Venda for Science and Technology, Private Bag X5050, Thohoyandou 0950, South Africa.
authors.forename: Nkhumeleni Jeoffrey
authors.initials: NJ
authors.lastname: Manenzhe
authors.forename: Natasha
authors.initials: N
authors.lastname: Potgieter
authors.forename: Teunis
authors.initials: T
authors.lastname: van Ree
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D032411:Lippia / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry; D010963:Plasmodium falciparum / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D009822:Oils, Volatile