Multivessel variant angina unresponsive to urapidil.
We present a case of variant angina complicated by recurrent sudden cardiac death. During coronary angiography a diffuse 3-vessel vasoconstriction was observed progressing to a more severe vasoconstriction in the mid LAD. Intracoronary administration of urapidil did not reverse the vasoconstriction of the LAD; instead an occlusive vasospasm occurred accompanied by marked ischaemia.
Vydt
Tom
T
Department of Internal medicine, AZ H. Hart, Lier, Belgium.
Wildiers
Antoon
A
Vrints
Christiaan J
CJ
D000368:Aged; D000788:Angina Pectoris, Variant / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy*; D015906:Angioplasty, Balloon, Coronary; D001281:Atrial Fibrillation / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D017023:Coronary Angiography; D003329:Coronary Vasospasm / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D003331:Coronary Vessels / Q000187:drug effects* / Q000503:physiopathology* / Q000601:surgery; D016757:Death, Sudden, Cardiac / Q000473:pathology; D004452:Echocardiography; D004562:Electrocardiography; D022062:Electrophysiologic Techniques, Cardiac; D006801:Humans; D008297:Male; D010879:Piperazines / Q000627:therapeutic use*; D014661:Vasoconstriction / Q000187:drug effects; D014665:Vasodilator Agents / Q000627:therapeutic use*
D010879:Piperazines; D014665:Vasodilator Agents; C015568:urapidil