title: Heroin profiling: mannitol hexaacetate as an unusual ingredient of some illicit drug seizures.
abstract: Mannitol hexaacetate (MHA) has been detected by GC-MS in some brown illicit drug seizures in which diacetylmorphine (DAM) was completely lacking. The presence of MHA as a genuine ingredient of the drug seizures rather than a storage- or an analytical artifact, formed by transacetylation of mannitol with the DAM in the heroin, has been verified. It is argued that MHA was formed as a result of the addition of mannitol, as diluent, before the acetylating step in the process of the heroin preparation. This early dilution in the production and distribution chain of the illicit drug is deemed as peculiar, nonetheless it may be highly indicative of a specific production process of heroin in a trafficking organization.
authors.affiliation: Sharjah Police Forensic Science Laboratory, Sharjah, United Arab Emirates. elhaj@emirates.net.ae
authors.forename: B M
authors.initials: BM
authors.lastname: El-Haj
authors.forename: A M
authors.initials: AM
authors.lastname: Al-Amri
authors.forename: H S
authors.initials: HS
authors.lastname: Ali
mesh_terms: D000085:Acetates; D005554:Forensic Medicine / Q000379:methods; D008401:Gas Chromatography-Mass Spectrometry; D003932:Heroin / Q000737:chemistry*; D013287:Illicit Drugs / Q000737:chemistry*; D008353:Mannitol / Q000031:analogs & derivatives* / Q000032:analysis*; D015394:Molecular Structure; D009294:Narcotics / Q000737:chemistry*
chemical_list: D000085:Acetates; D013287:Illicit Drugs; D009294:Narcotics; C495398:mannitol hexaacetate; D008353:Mannitol; D003932:Heroin