title: Characterization of a pigeon paramyxovirus (PPMV-1) isolated from chickens in South Africa.
abstract: A paramyxovirus with a thermostability of 60 min (typical of velogenic viruses) and a mean death time of > 90 h (typical of lentogenic viruses) was isolated from layers near Mooi River, South Africa. Our results, based on comparative nucleotide sequence data indicated that the virus is pigeon paramyxovirus 1 (PPMV-1), a variant of Newcastle disease virus. The F0 cleavage site contains a 112RRKKRF117 motif, and the virus had 98% sequence identity with PPMV-1 strains from the Far East. PPMV-1 was last reported in South Africa during the 1980s, with this being the first report of PPMV-1 isolated from chickens in South Africa.
authors.affiliation: Biotechnology Division, Onderstepoort Veterinary Institute, Private Bag X05, Pretoria, 0110, South Africa.
authors.forename: C
authors.initials: C
authors.lastname: Abolnik
authors.forename: R F
authors.initials: RF
authors.lastname: Horner
authors.forename: R
authors.initials: R
authors.lastname: Maharaj
authors.forename: G J
authors.initials: GJ
authors.lastname: Viljoen
mesh_terms: D000818:Animals; D002645:Chickens; D010856:Columbidae; D005814:Genes, Viral; D009521:Newcastle Disease / Q000821:virology*; D009522:Newcastle disease virus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D010802:Phylogeny; D011201:Poultry Diseases / Q000821:virology*; D012367:RNA, Viral / Q000032:analysis; D013019:South Africa; D014774:Virulence
chemical_list: D012367:RNA, Viral