title: [Clinical study of shuizhitong capsule in treating senile vascular dementia].
abstract: OBJECTIVE
  To observe the clinical therapeutic effect of Shuizhitong capsule (SZT) in treating senile vascular dementia (VD) and on changes of related physio-chemical criteria.
  
  
  METHODS
  Eighty-five patients with VD were randomly divided into the treated group (n = 51) and the control group (n = 34) in the ratio of 3:2, treated with SZT and Piracetam respectively. Before and after treatment, the Zhang's Dementia Scoring (HDS) and Function of Social Activity Questionnaire (FAQ) scoring, cerebral blood flow and hemorrheologic properties were determined.
  
  
  RESULTS
  SZT could significantly improve the patients' clinical symptoms, intracranial hemodynamic condition and the hyperviscosity, hypercoagulation and hyperaggregation status, lower the whole blood and plasma specific viscosity, raise the living standard of partial patients, with significant difference between before and after treatment (P < 0.05).
  
  
  CONCLUSIONS
  The therapeutic effect of SZT in treating senile VD is definite.
authors.affiliation: The Third Affiliated Hospital of Henan TCM College, Zhengzhou (450000). xifenli@yahoo.com
authors.forename: Xue-zhong
authors.initials: XZ
authors.lastname: Fan
authors.forename: Bao-lin
authors.initials: BL
authors.lastname: Yang
mesh_terms: D000368:Aged; D001809:Blood Viscosity / Q000187:drug effects; D002214:Capsules; D002560:Cerebrovascular Circulation / Q000187:drug effects; D015140:Dementia, Vascular / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D018056:Hemorheology / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D018697:Nootropic Agents / Q000627:therapeutic use*; D008517:Phytotherapy
chemical_list: D002214:Capsules; D004365:Drugs, Chinese Herbal; D018697:Nootropic Agents