Long-term metabolic, cardiovascular and neoplastic risks with polycystic ovary syndrome.
Metabolic abnormalities and obesity have long been associated with the development of cardiovascular disease in the general population. These same features are also associated with polycystic ovary syndrome (PCOS). An increased prevalence of hypertension, dyslipidaemia, obesity and hyperinsulinaemia, as well as changes in coagulation and blood vessel function, provide an explanation as to why women with PCOS are at an increased risk of developing cardiovascular disease over the long term.
Cattrall
Fleur R
FR
Department of Obstetrics and Gynaecology, Monash University, Level 5, Monash Medical Centre, 246 Clayton Road, Clayton, Melbourne 3168, Australia. fleurcat@hotmail.com
Healy
David L
DL
D002318:Cardiovascular Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D024821:Metabolic Syndrome / Q000209:etiology; D009369:Neoplasms / Q000209:etiology*; D009765:Obesity / Q000150:complications; D011085:Polycystic Ovary Syndrome / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D012307:Risk Factors