Detection of unusual lipid mixing in cholesterol-rich phospholipid bilayers: the long and the short of it.
Nearest-neighbor recognition studies have revealed that favored sterol-phospholipid associations can be reversed in a fluid bilayer that contains relatively long (high melting) and short (low melting) phospholipids, when the sterol content is sufficiently high; that is, like-lipids now become favored nearest-neighbors. A possible origin of this effect is briefly discussed.
Tokutake
Nobuya
N
Department of Chemistry, Lehigh University, Bethlehem, PA 18015, USA.
Jing
Bingwen
B
Regen
Steven L
SL
D002784:Cholesterol / Q000737:chemistry*; D007700:Kinetics; D008051:Lipid Bilayers / Q000737:chemistry*; D010743:Phospholipids / Q000737:chemistry*; D013261:Sterols / Q000737:chemistry
D008051:Lipid Bilayers; D010743:Phospholipids; D013261:Sterols; D002784:Cholesterol