Effect of two inhibitors on succinic dehydrogenase activity in cerebral hemispheres of male garden lizards of three different age groups.
Age changes in the specific activity of cerebral succinic dehydrogenase (SDH) and the effect of two inhibitors (malonate and p-chlorophenoxy acetic acid) on enzyme activity were traced in a short-lived species of reptile, Calotes versicolor, the garden lizard. The enzyme activity reached a peak level in middle-aged lizards followed by a decline in old counterparts. The enzyme inhibitions by both the inhibitors were significantly higher in old than in middle-aged and young lizards suggesting a change in specificity of SDH molecules during ageing.
Mishra
P N
PN
Department of Zoology, Khallikote College, Berhampur, Orissa, India.
Patnaik
B K
BK