Surgical and clinical management of a patient with Glanzmann thrombasthenia: a case report.
A 6-year-old girl with Glanzmann thrombasthenia presented with caries and periapical lesions in the primary mandibular second molars and moderate gingivitis of the maxillary and mandibular anterior teeth. Dental extraction was recommended, and before every surgical intervention, the patient underwent platelet-concentrate transfusion to prevent hemorrhage. Epsilon aminocaproic acid was administered 6 hours before, and 48 hours after every dental procedure to prevent bleeding. In this case, treatment was effective in the prevention of hemorrhagic complications, during the required dental procedures.
Fernandes Gomes
Mônica
M
Department of Biosciences and Oral Diagnosis, São José dos Campos Dental School, São Paulo State University-UNESP, São Paulo, Brazil. mfgomes@fosjc.unesp.br
de Melo
Renata Marques
RM
Plens
Glauco
G
Pontes
Elitânia Marinho
EM
Silva
Marcelo Milone
MM
da Rocha
João Carlos
JC
D000614:Aminocaproates / Q000627:therapeutic use; D002648:Child; D017742:Dental Care for Chronically Ill; D003731:Dental Caries / Q000628:therapy; D005260:Female; D006801:Humans; D006472:Oral Hemorrhage / Q000517:prevention & control; D010485:Periapical Periodontitis / Q000628:therapy; D013915:Thrombasthenia / Q000150:complications; D014081:Tooth Extraction; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
D000614:Aminocaproates; D014662:Vasoconstrictor Agents