Nutritional requirements of Allisonella histaminiformans, a ruminal bacterium that decarboxylates histidine and produces histamine.
Histamine is an inflammatory agent that contributes to bovine laminitis. Cattle fed silage-containing rations often have large populations of Allisonella histaminiformans, but this obligate histidine-decarboxylating bacterium could not be isolated from cattle fed timothy hay. The growth of A. histaminiformans was stimulated by yeast extract, protein hydrolysates, and water-soluble extracts of alfalfa or corn silage. Extracts of alfalfa were more potent than corn silage. Because growth and histamine production were not stimulated by Casamino Acids or a mixture of purified amino acids, it appeared that A. histaminiformans requires peptides. The idea that A. histaminiformans requires peptides is consistent with the observation that alfalfa silages often have a large amount of peptide nitrogen.
Garner
Matthew R
MR
Department of Microbiology, Cornell University, Ithaca, NY 14853, USA.
Gronquist
Matthew R
MR
Russell
James B
JB
D000821:Animal Feed / Q000382:microbiology; D000818:Animals; D002417:Cattle; D003470:Culture Media; D006632:Histamine / Q000096:biosynthesis*; D006639:Histidine / Q000378:metabolism*; D006640:Histidine Decarboxylase / Q000378:metabolism*; D000455:Medicago sativa / Q000378:metabolism; D012417:Rumen / Q000382:microbiology*; D012820:Silage / Q000382:microbiology*; D045854:Veillonellaceae / Q000201:enzymology / Q000378:metabolism*; D003313:Zea mays / Q000378:metabolism
D003470:Culture Media; D006639:Histidine; D006632:Histamine; D006640:Histidine Decarboxylase