title: Non-Hodgkin lymphoma in a child with Williams syndrome.
abstract: Non-Hodgkin lymphoma in an 8-year-old boy with Williams syndrome is reported. Molecular DNA analysis showed a maternal deletion at 7q11.23, the locus of elastin and several other genes, including the BCL7B gene, involved in early development. To our knowledge, this is the second reported case of a lymphoma in a Williams syndrome patient and the first in a child.
authors.affiliation: Medical Genetics, Athens University School of Medicine, Choremio Research Laboratory, Aghia Sophia Children's Hospital, Athens PC 11527, Greece.
authors.forename: Styliani
authors.initials: S
authors.lastname: Amenta
authors.forename: Maria
authors.initials: M
authors.lastname: Moschovi
authors.forename: Christalena
authors.initials: C
authors.lastname: Sofocleous
authors.forename: Stavroula
authors.initials: S
authors.lastname: Kostaridou
authors.forename: Ariadni
authors.initials: A
authors.lastname: Mavrou
authors.forename: Helen
authors.initials: H
authors.lastname: Fryssira
mesh_terms: D002051:Burkitt Lymphoma / Q000209:etiology / Q000235:genetics*; D002648:Child; D002872:Chromosome Deletion; D002897:Chromosomes, Human, Pair 7; D006801:Humans; D007078:Ileal Neoplasms / Q000209:etiology / Q000235:genetics; D008297:Male; D011506:Proteins / Q000235:genetics; D018980:Williams Syndrome / Q000150:complications / Q000235:genetics*
chemical_list: C116387:BCL7B protein, human; D011506:Proteins