Isolation and characterization of five new tetrasaccharide glycosides from the roots of Ipomoea stans and their cytotoxic activity.
Five new tetrasaccharide glycosides, stansins 1-5, were isolated from the roots of Ipomoea stans, and their structures were elucidated using spectroscopic and chemical methods. Preliminary testing showed the cytotoxicity of 5 toward the OVCAR and UISO-SQC-1 cancer cell lines.
León
Ismael
I
Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos, Avenida Universidad 1001, Col. Chamilpa 62210 Cuernavaca, Morelos, México. ismaelr@ciq.uaem.mx
Enríquez
Raúl G
RG
Gnecco
Dino
D
Villarreal
María L
ML
Cortés
Daniel Alonso
DA
Reynolds
William F
WF
Yu
Margaret
M
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D027741:Ipomoea / Q000737:chemistry*; D008800:Mexico; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011134:Polysaccharides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013329:Structure-Activity Relationship; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D006027:Glycosides; D011134:Polysaccharides