title: Tetracyclic triterpenoids from the leaves of Azadirachta indica.
abstract: Two new tetracyclic triterpenoids zafaral [24,25,26,27-tetranorapotirucalla-(apoeupha)-6alpha-methoxy-7alpha-acetoxy-1,14-dien-3,16-dione-21-al] (1) and meliacinanhydride [24,25,26,27-tetranorapotirucalla-(apoeupha)-6alpha-hydroxy,11alpha-methoxy-7alpha,12alpha-diacetoxy,1,14,20(22)-trien-3-one] (2) have been isolated from the methanolic extract of neem leaves along with two known constituents nimocinol and isomeldenin. Their structures and the relative configurations were determined by spectroscopic methods ((1)H and (13)C NMR, IR, and MS) and 2D NMR experiments.
authors.affiliation: International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, 75270, Pakistan. bina@khi.comsats.net.pk
authors.forename: Bina S
authors.initials: BS
authors.lastname: Siddiqui
authors.forename: Farhana
authors.initials: F
authors.lastname: Afshan
authors.forename: Tahsin
authors.initials: T
authors.lastname: Gulzar
authors.forename: Muddasar
authors.initials: M
authors.lastname: Hanif
mesh_terms: D031601:Azadirachta / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D000432:Methanol / Q000737:chemistry; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013729:Terpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D010936:Plant Extracts; D013729:Terpenes; D000432:Methanol