title: Analysis of potassium spectra with low counting statistics using trapezoidal and library least-squares methods.
abstract: Potassium spectra with low counting statistics were measured with a NaI detector from a water phantom, simulating a brain, and were analyzed for error propagation in determination of K employing either the Trapezoidal Method or the Library Least-Squares method. We demonstrate, using measured and synthetic spectra, that a smaller error is obtained in the analysis of potassium when using the Library Least-Squares method.
authors.affiliation: Brookhaven National Laboratory, Medical Department, Upton, NY 11973, USA.
authors.forename: L M
authors.initials: LM
authors.lastname: Ramirez
authors.forename: L
authors.initials: L
authors.lastname: Wielopolski
mesh_terms: D000465:Algorithms; D001921:Brain / Q000000981:diagnostic imaging* / Q000378:metabolism*; D003198:Computer Simulation; D016018:Least-Squares Analysis; D008954:Models, Biological; D015233:Models, Statistical; D019047:Phantoms, Imaging; D049268:Positron-Emission Tomography; D011188:Potassium / Q000378:metabolism*; D011197:Potassium Radioisotopes / Q000493:pharmacokinetics*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D011197:Potassium Radioisotopes; D019275:Radiopharmaceuticals; D011188:Potassium