ABO-incompatible kidney transplantation.
When a renal transplant candidate's only medically-acceptable living kidney donor is ABO incompatible, the most common practice is to place them on the deceased donor list. Over the past few years, the implementation of paired kidney donor exchange programs and the development of protocols to overcome the ABO blood group barrier have become much more successful and widespread. Here we review the therapeutic options for patients whose only living kidney donor is ABO incompatible, with a specific emphasis on the rationale for and the current outcomes of ABO incompatible living donor kidney transplantation.
Stegall
Mark D
MD
Department of Surgery, Division of Transplantation Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA. stegall.mark@mayo.edu
Dean
Patrick G
PG
Gloor
James M
JM
D000017:ABO Blood-Group System / Q000276:immunology*; D001787:Blood Group Incompatibility; D002102:Cadaver; D006085:Graft Survival / Q000276:immunology; D006801:Humans; D016030:Kidney Transplantation / Q000276:immunology*; D019520:Living Donors; D014019:Tissue Donors; D014850:Waiting Lists
D000017:ABO Blood-Group System