Topical imiquimod treatment of lentigo maligna: clinical and histologic evaluation.
We have treated extensive lentigo maligna in two elderly patients with Imiquimod 5% (Aldara). It was applied 3 times weekly, for 3 to 5 months. Clinical and histological remission was observed over 13 months of follow-up care. Tolerance was good. We suggest that topical imiquimod could be an interesting therapeutic alternative.
Kupfer-Bessaguet
I
I
Department of Dermatology, Laboratory of Pathology, University Hospital Morvan, Brest, France.
Guillet
G
G
Misery
L
L
Carre
J L
JL
Leroy
J P
JP
Sassolas
Bruno
B
D000287:Administration, Topical; D000368:Aged; D000369:Aged, 80 and over; D000634:Aminoquinolines / Q000008:administration & dosage*; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001706:Biopsy; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D018327:Hutchinson's Melanotic Freckle / Q000188:drug therapy* / Q000473:pathology*; D000077271:Imiquimod; D008297:Male; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D016896:Treatment Outcome
D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod