title: Extra-esophageal disorders in gastroesophageal reflux disease.
abstract: Gastroesophageal reflux disease (GERD) is a common condition that effects about 10% of the adult population comprising a broad spectrum of symptoms and varying degrees of severity and frequency. Extra-esophageal manifestations are increasingly being recognized. Up to 50% of patients with an endoscopically proven or negative esophagitis suffer from symptoms other than heartburn or acid regurgitation such as laryngitis, hoarseness, chronic cough, asthma, or non-cardiac chest pain. The therapy of choice is proton pump inhibitors.
authors.affiliation: Academic Teaching Hospital, University of Marburg, Germany. d.jaspersen.medII@klinikum-fulda.de
authors.forename: Daniel
authors.initials: D
authors.lastname: Jaspersen
mesh_terms: D001249:Asthma / Q000209:etiology; D003371:Cough / Q000209:etiology; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D007827:Laryngitis / Q000209:etiology; D009853:Omeprazole / Q000627:therapeutic use*; D054328:Proton Pump Inhibitors
chemical_list: D004791:Enzyme Inhibitors; D054328:Proton Pump Inhibitors; D009853:Omeprazole