title: Left ventricular hypertrabeculation/noncompaction and neuromuscular disorders in idiopathic dilated cardiomyopathy.
abstract: OBJECTIVE
  Our aim was to assess 1) the association of idiopathic dilative cardiomyopathy (IDC) and left ventricular hypertrabeculation/noncompaction (LVHT), 2) the use of cardiac magnetic resonance imaging (CMRI) in IDC and 3) the association of IDC and neuromuscular disorders (NMD).
  
  
  METHODS
  Patients in whom coronary heart disease had been excluded by coronary angiography and whose left ventricular end diastolic diameter was > 59 mm and fractional shortening < 25% with no other causes of cardiac dysfunction, were invited to participate.
  
  
  RESULTS
  Among 25 patients, 18 refused CMRI (claustrophobia n = 13, inability to lie flat n = 5), thus 7 patients (2 female, 47-66 years) were included. LVHT was found in 5/7 cases. In 4/5 patients who were neurologically investigated, a NMD was found. In 2/7 cases echocardiography failed to visualise the ventricular apex.
  
  
  CONCLUSIONS
  Patients with IDC should be investigated neurologically. In IDC patients with poor echocardiographic quality CMRI should be applied.
authors.affiliation: 2nd Medical Department, Krankenanstalt Rudolfstiftung, Wien, Austria. claudia.stoellberger@chello.at
authors.forename: Claudia
authors.initials: C
authors.lastname: Stöllberger
authors.forename: Silvia
authors.initials: S
authors.lastname: Leitner
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Kopsa
authors.forename: Josef
authors.initials: J
authors.lastname: Finsterer
mesh_terms: D000368:Aged; D001317:Austria; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis* / Q000209:etiology* / Q000378:metabolism; D017023:Coronary Angiography; D004452:Echocardiography; D004562:Electrocardiography; D004576:Electromyography; D005260:Female; D005500:Follow-Up Studies; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000175:diagnosis* / Q000209:etiology* / Q000378:metabolism; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000201:enzymology / Q000473:pathology / Q000648:ultrastructure; D009468:Neuromuscular Diseases / Q000175:diagnosis* / Q000209:etiology* / Q000378:metabolism; D011446:Prospective Studies; D012680:Sensitivity and Specificity