title: First encounter: how pathogens compromise epithelial transport.
abstract: Pathogenic organisms trigger numerous signaling pathways that ultimately lead to drastic changes in physiological functions. Apart from altering structure and function of the epithelial tight junction barrier and activating inflammatory cascades, they induce changes in fluid and electrolyte transport. Pathogens do so by activating or by inhibiting ion channels and transporters, and the result might be to their benefit or to their disadvantage.
authors.affiliation: Institut für Physiologie, Universität Regensburg, D-93053 Regensburg, Germany. uqkkunze@mailbox.uq.edu.au
authors.forename: Karl
authors.initials: K
authors.lastname: Kunzelmann
authors.forename: Brendan
authors.initials: B
authors.lastname: McMorran
mesh_terms: D000818:Animals; D001424:Bacterial Infections / Q000378:metabolism*; D001692:Biological Transport / Q000502:physiology; D002462:Cell Membrane / Q000378:metabolism / Q000382:microbiology; D004847:Epithelial Cells / Q000378:metabolism* / Q000382:microbiology*; D006801:Humans