title: Stochastic league tables: an application to diabetes interventions in the Netherlands.
abstract: The aim of this paper is to discuss the use of stochastic league tables approach in cost-effectiveness analysis of diabetes interventions. It addresses the common grounds and differences with other methods of presenting uncertainty to decision-makers. This comparison uses the cost-effectiveness results of medical guidelines for Dutch diabetes type 2 patients in primary and secondary care. Stochastic league tables define the optimum expansion pathway as compared to baseline, starting with the least costly and most cost-effective intervention mix. Multi-intervention cost-effectiveness acceptability curves are used as a way to represent uncertainty information on the cost-effectiveness of single interventions as compared to a single alternative. The stochastic league table for diabetes interventions shows that in case of low budgets treatment of secondary care patients is the most likely optimum choice. Current care options of diabetes complications are shown to be inefficient compared to guidelines treatment. With more resources available one may implement all guidelines and improve efficiency. The stochastic league table approach and multi-intervention cost-effectiveness acceptability curves in uncertainty analysis lead to similar results. In addition, the stochastic league table approach provides policy makers with information on affordability by budget level. It fulfils more adequately the information requirements to choose between interventions, using the efficiency criterion.
authors.affiliation: Global Programme on Evidence for Health Policy, World Health Organization (WHO), Geneva, Switzerland.
authors.forename: Raymond C W
authors.initials: RC
authors.lastname: Hutubessy
authors.forename: Louis W
authors.initials: LW
authors.lastname: Niessen
authors.forename: Rob F
authors.initials: RF
authors.lastname: Dijkstra
authors.forename: Ton F
authors.initials: TF
authors.lastname: Casparie
authors.forename: Frans F
authors.initials: FF
authors.lastname: Rutten
mesh_terms: D002985:Clinical Protocols; D003362:Cost-Benefit Analysis / Q000379:methods*; D003657:Decision Making; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000191:economics* / Q000628:therapy*; D006801:Humans; D015993:Life Tables; D017059:Models, Econometric; D009010:Monte Carlo Method; D009426:Netherlands; D017410:Practice Guidelines as Topic; D011320:Primary Health Care / Q000191:economics* / Q000592:standards; D019057:Quality-Adjusted Life Years; D013269:Stochastic Processes; D035501:Uncertainty