title: Isolation, structure determination and biological activity of 15-deoxo-7,32-O-didesmethylrapamycin from the soil actinomycete LL-D45042.
authors.affiliation: Department of Chemical & Screening Sciences, Oncology, Wyeth Research, 401 North Middletown Road, Pearl River, New York, 10965, USA. graziaei@wyeth.com
authors.forename: Edmund I
authors.initials: EI
authors.lastname: Graziani
authors.forename: Mia Y
authors.initials: MY
authors.lastname: Summers
authors.forename: Jeffrey E
authors.initials: JE
authors.lastname: Janso
authors.forename: Ker
authors.initials: K
authors.lastname: Yu
authors.forename: Valerie S
authors.initials: VS
authors.lastname: Bernan
authors.forename: Michael
authors.initials: M
authors.lastname: Greenstein
authors.forename: Guy T
authors.initials: GT
authors.lastname: Carter
mesh_terms: D039903:Actinobacteria / Q000378:metabolism*; D020123:Sirolimus / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism / Q000494:pharmacology; D012988:Soil Microbiology; D013329:Structure-Activity Relationship
chemical_list: C492085:15-deoxo-7,32-O-didesmethylrapamycin; D020123:Sirolimus