title: [Spinal intramedullary tumors. When is surgical treatment indicated?].
abstract: OBJECTIVE
  Timing of surgery in patients with intramedullary tumors is the subject of controversy. The aim of this retrospective study is to evaluate whether patients with intramedullary ependymomas and astrocytomas have a better postoperative prognosis without or with slight preoperative deficits than those with severe preoperative neurological disturbances.
  
  
  METHODS
  During a period of 8.5 years (January 1992-August 2000), 34 patients with intramedullary tumors underwent surgery in our Neurosurgical Department. Among them there were five astrocytomas WHO grade II and ten ependymomas WHO grade II. Recurrences were observed in two patients with astrocytomas and one patient with ependymoma. Pre- and postoperative functional performance was classified according to the McCormick scale in grade I-IV (grade I: neurologically normal or mild focal deficit and grade IV: severe neurological deficits and without functional independence). The follow-up period varied from 4 to 76 months (mean: 27.9 months).
  
  
  RESULTS
  All seven grade I patients remained unchanged after surgery. Two of four grade II patients improved to grade I; two deteriorated to grade III. Two of three grade III and IV patients remained unchanged and another one deteriorated from grade III to IV.
  
  
  CONCLUSIONS
  At the best, intramedullary astrocytomas and ependymomas should be operated when symptoms are mild. Early surgery can achieve good functional outcome.
authors.affiliation: Neurochirurgische Klinik, Universität Ulm, 89312 Günzburg. gregor.antoniadis@medizin.uni-ulm.de
authors.forename: G
authors.initials: G
authors.lastname: Antoniadis
authors.forename: M
authors.initials: M
authors.lastname: Engelhardt
authors.forename: W
authors.initials: W
authors.lastname: Börm
authors.forename: H-P
authors.initials: HP
authors.lastname: Richter
authors.forename: S A
authors.initials: SA
authors.lastname: Rath
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control*; D011300:Preoperative Care / Q000379:methods*; D020127:Recovery of Function; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D013120:Spinal Cord Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery*; D016896:Treatment Outcome
vernacular_title: Spinale intramedulläre Tumoren Wann ist die operative Behandlung angezeigt?