title: A survey of the year 2003 literature on applications of isothermal titration calorimetry.
abstract: Over the last decade isothermal titration calorimetry (ITC) has developed from a specialist method which was largely restricted in its use to dedicated experts, to a major, commercially available tool in the arsenal directed at understanding molecular interactions. The number of those proficient in this field has multiplied dramatically, as has the range of experiments to which this method has been applied. This has led to an overwhelming amount of new data and novel applications to be assessed. With the increasing number of publications in this field comes a need to highlight works of interest and impact. In this overview of the literature we have attempted to draw attention to papers and issues for which both the experienced calorimetrist and the interested dilettante hopefully will share our enthusiasm.
authors.affiliation: Department of Biochemistry and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Cliff
authors.forename: Aldo
authors.initials: A
authors.lastname: Gutierrez
authors.forename: John E
authors.initials: JE
authors.lastname: Ladbury
mesh_terms: D002151:Calorimetry / Q000379:methods*; D046912:Multiprotein Complexes / Q000737:chemistry / Q000378:metabolism; D013816:Thermodynamics
chemical_list: D046912:Multiprotein Complexes