title: Desflurane used in a patient with congenital insensitivity to pain with anhidrosis during septic shock.
abstract: Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autonomic recessive disorder characterized by congenital analgesia, absence of sweating and mental retardation. Because of these abnormalities, the anesthetic managements in patients with CIPA deserve special attention. Here we report a 22-year-old man with CIPA receiving left above-knee amputation due to severe lower extremity infection. General anesthesia was maintained with desflurane, an intervention that has never been reported, and the whole course of operation was uneventful. This is also the first reported case of CIPA in Taiwan.
authors.affiliation: Department of Anesthesiology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
authors.forename: Sheng-Chin
authors.initials: SC
authors.lastname: Kao
authors.forename: Chien-Kun
authors.initials: CK
authors.lastname: Ting
authors.forename: Kai-Wen
authors.initials: KW
authors.lastname: Cheng
authors.forename: Su-Man
authors.initials: SM
authors.lastname: Lin
authors.forename: Mei-Yung
authors.initials: MY
authors.lastname: Tsou
authors.forename: Kwok-Hon
authors.initials: KH
authors.lastname: Chan
authors.forename: Shen-Kou
authors.initials: SK
authors.lastname: Tsai
mesh_terms: D000328:Adult; D000077335:Desflurane; D009477:Hereditary Sensory and Autonomic Neuropathies / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007530:Isoflurane / Q000008:administration & dosage* / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000627:therapeutic use; D012772:Shock, Septic / Q000150:complications*; D013624:Taiwan; D016896:Treatment Outcome
chemical_list: D018696:Neuroprotective Agents; D000077335:Desflurane; D007530:Isoflurane