Effect of organosoluble salts on the nanofibrous structure of electrospun poly(3-hydroxybutyrate-co-3-hydroxyvalerate).
Electrospinning of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) in chloroform was investigated to develop non-woven biodegradable nanofibrous structures for tissue engineering. Ultrafine PHBV fibers were obtained by electrospinning of 20 wt.% PHBV solution in chloroform and the resulting fiber diameters were in the range of 1.0-4.0 microm. When small amounts of benzyl trialkylammonium chlorides were added to the PHBV solution, the average diameter was decreased to 1.0 microm and the fibers were amounted in a straight shape. Conductivity of the PHBV solution was a major parameter affecting the morphology and diameter of the electrospun PHBV fibers. PHBV non-woven structures electrospun with salt exhibited a higher degradation rate than those prepared without salt probably due to the increase of surface area of PHBV fibers.
Choi
Jae Shin
JS
Department of Textile Engineering, Chungnam National University, Daejon 305 764, South Korea.
Lee
Sung Won
SW
Jeong
Lim
L
Bae
Su-Hyun
SH
Min
Bum Chan
BC
Youk
Ji Ho
JH
Park
Won Ho
WH
D000643:Ammonium Chloride / Q000737:chemistry; D001672:Biocompatible Materials; D002725:Chloroform; D004305:Dose-Response Relationship, Drug; D008855:Microscopy, Electron, Scanning; D008956:Models, Chemical; D036103:Nanotechnology; D011091:Polyesters / Q000737:chemistry* / Q000494:pharmacology*; D000644:Quaternary Ammonium Compounds / Q000737:chemistry; D012492:Salts / Q000737:chemistry; D013997:Time Factors; D000094122:Polyhydroxybutyrates
D000643:Ammonium Chloride; D001672:Biocompatible Materials; D002725:Chloroform; D011091:Polyesters; D000644:Quaternary Ammonium Compounds; D012492:Salts; C052620:poly(3-hydroxybutyrate)-co-(3-hydroxyvalerate); D000094122:Polyhydroxybutyrates