Desflurane used in a patient with congenital insensitivity to pain with anhidrosis during septic shock.
Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autonomic recessive disorder characterized by congenital analgesia, absence of sweating and mental retardation. Because of these abnormalities, the anesthetic managements in patients with CIPA deserve special attention. Here we report a 22-year-old man with CIPA receiving left above-knee amputation due to severe lower extremity infection. General anesthesia was maintained with desflurane, an intervention that has never been reported, and the whole course of operation was uneventful. This is also the first reported case of CIPA in Taiwan.
Kao
Sheng-Chin
SC
Department of Anesthesiology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Ting
Chien-Kun
CK
Cheng
Kai-Wen
KW
Lin
Su-Man
SM
Tsou
Mei-Yung
MY
Chan
Kwok-Hon
KH
Tsai
Shen-Kou
SK
D000328:Adult; D000077335:Desflurane; D009477:Hereditary Sensory and Autonomic Neuropathies / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007530:Isoflurane / Q000008:administration & dosage* / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000627:therapeutic use; D012772:Shock, Septic / Q000150:complications*; D013624:Taiwan; D016896:Treatment Outcome
D018696:Neuroprotective Agents; D000077335:Desflurane; D007530:Isoflurane