title: Pitfalls in the imaging diagnosis of hepatocellular nodules in the cirrhotic and noncirrhotic liver.
abstract: Contrast-enhanced CT and MR are the most commonly used modalities for objective evaluation of hepatocellular nodules. Various types of pseudolesions as seen on CT or MR have been reported, which are attributable to either focal alteration in hemodynamics or parenchymal metabolism, or to both. Pseudolesions specifically seen in cirrhotic liver include arterio-portal shunt, regenerating or hyperplastic nodules, and confluent fibrosis. In noncirrhotic liver, transient focal compression to the liver, third inflow other than normal hepatic arterial and portal venous flow, and vessel compromise are the causes of pseudolesions. To understand the characteristic features of these pseudolesions, and their underlying mechanism as well, is important for proper diagnosis of true hepatocellular lesions.
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. yoshimitsu@dr.hosp.kyushu-u.ac.jp
authors.forename: Kengo
authors.initials: K
authors.lastname: Yoshimitsu
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Irie
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Aibe
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Tajima
authors.forename: Akihiro
authors.initials: A
authors.lastname: Nishie
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Asayama
authors.forename: Kunishige
authors.initials: K
authors.lastname: Matake
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Nakayamka
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kakihara
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Honda
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000098:blood supply / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D006801:Humans; D008099:Liver / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000473:pathology*; D008103:Liver Cirrhosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008113:Liver Neoplasms / Q000098:blood supply / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D009389:Neovascularization, Pathologic; D014057:Tomography, X-Ray Computed