title: Serum inhibin A, inhibin B, pro-alphaC, and activin A levels in women with idiopathic premature ovarian failure.
abstract: Serum inhibin A, inhibin B, pro-alphaC, and activin A levels in 30 women with idiopathic premature ovarian failure (POF), 30 postmenopausal women, and 30 age-matched fertile women were determined. Women with POF showed low levels of inhibin A and inhibin B, but not of activin A, whereas the levels of pro-alphaC were significantly higher than in postmenopausal women. Thus, the circulating level of pro-alphaC could be a marker for assessing residual ovarian function in women with POF.
authors.affiliation: Department of Obstetrics and Gynecology, University of Saarland, Kirrberger Strasse, Homburg/Saar 66421, Germany. frwmun@uniklinik-saarland.de
authors.forename: Winfried
authors.initials: W
authors.lastname: Munz
authors.forename: Mohamed Eid
authors.initials: ME
authors.lastname: Hammadeh
authors.forename: Rudolf
authors.initials: R
authors.lastname: Seufert
authors.forename: Michael
authors.initials: M
authors.lastname: Schaffrath
authors.forename: Werner
authors.initials: W
authors.lastname: Schmidt
authors.forename: Kunhard
authors.initials: K
authors.lastname: Pollow
mesh_terms: D005260:Female; D006801:Humans; D007265:Inhibins / Q000097:blood*; D017698:Postmenopause; D016649:Primary Ovarian Insufficiency / Q000097:blood*; D011498:Protein Precursors / Q000097:blood*
chemical_list: D011498:Protein Precursors; C422362:inhibin A; C422364:inhibin B; C095971:inhibin-alpha subunit precursor; D007265:Inhibins