title: Parathyroid carcinoma: a multicenter review of clinicopathologic features and treatment outcomes.
abstract: We conducted a retrospective study of 13 patients with parathyroid carcinoma to assess their clinical characteristics and surgical outcomes. Study parameters included patient demographics, survival, treatment response, and recurrence. We found that all patients who had undergone local tumor excision developed a recurrence, compared with only 33% of those available for follow-up after en bloc tumor resection. Based on these findings, we recommend en bloc tumor resection as the initial treatment of choice for patients diagnosed with parathyroid carcinoma.
authors.affiliation: Department of Surgery, St. Paul's Hospital, University of British Columbia, Vancouver. smwiseman@providencehealth.bc.ca
authors.forename: Sam M
authors.initials: SM
authors.lastname: Wiseman
authors.forename: Nestor R
authors.initials: NR
authors.lastname: Rigual
authors.forename: Wesley L
authors.initials: WL
authors.lastname: Hicks
authors.forename: Saurin R
authors.initials: SR
authors.lastname: Popat
authors.forename: John M
authors.initials: JM
authors.lastname: Lore
authors.forename: Wade G
authors.initials: WG
authors.lastname: Douglas
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Jacobson
authors.forename: Dongfeng
authors.initials: D
authors.lastname: Tan
authors.forename: Thom R
authors.initials: TR
authors.lastname: Loree
mesh_terms: D000328:Adult; D002277:Carcinoma / Q000473:pathology* / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010282:Parathyroid Neoplasms / Q000473:pathology* / Q000628:therapy*; D012189:Retrospective Studies; D016896:Treatment Outcome