title: [Evaluation of parameters for the differentiation of acute from chronic renal failure in the dog].
abstract: The differentiation of acute (ARF) from chronic (CRF) renal failure is important for therapeutic and prognostic reasons and should be established as soon as possible. In practice this differentiation is often based on history, physical examination and laboratory results. In this retrospective study the diagnostic accuracy of parameters to differentiate ARF from CRF was tested in 19 dogs with ARF and 49 dogs with CRF. The diagnostic accuracy of body condition was 65%, of the hematocrit 78%, of serum potassium levels 28%, of total CO2 48%, of urinary casts 77%, of glucosuria 90% and of the urine protein-to-urine creatinine ratio 43%. Of all the parameters evaluated only glucosuria revealed an acceptable discriminating quality with a sensitivity of 92% and a specificity of 89%. A limitation of this factor is, that glucosuria depends on the cause of ARF. The single parameters tested are not very useful and the diagnosis of ARF or CRF is based on a combination of parameters from history, physical examination, laboratory results and diagnostic imaging. If a diagnosis can't be established immediately, treatment for ARF is recommended. With an immediate, aggressive treatment the possibility of total recovery from ARF is increased.
authors.affiliation: Klinik für Kleintiermedizin, Departement Kleintiere, Universität Zürich. bgerber@vetclinics.unizh.ch
authors.forename: B
authors.initials: B
authors.lastname: Gerber
authors.forename: T M
authors.initials: TM
authors.lastname: Glaus
authors.forename: S
authors.initials: S
authors.lastname: Unterer
authors.forename: C E
authors.initials: CE
authors.lastname: Reusch
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood / Q000175:diagnosis / Q000662:veterinary*; D000818:Animals; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D004283:Dog Diseases / Q000097:blood / Q000175:diagnosis*; D004285:Dogs; D005260:Female; D006029:Glycosuria / Q000175:diagnosis / Q000662:veterinary*; D007676:Kidney Failure, Chronic / Q000097:blood / Q000175:diagnosis / Q000662:veterinary*; D008297:Male; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
vernacular_title: Beurteilung von Parametern zur Unterscheidung von akuter und chronischer Niereninsuffizienz beim Hund.