Composition and antimicrobial activities of volatile components of Lippia javanica.
The volatile oil of Lippia javanica was prepared by hydrodistillation of leaves, flowers and stems, and characterized by GC-MS. The major component was 3-methyl-6-(1-methylethylidene)-cyclohex-2-en-1-one. The oil was tested for antimicrobial activity on cultures of Escherichia coli, Bacillus subtilis and Staphylococcus aureus, and found to inhibit E. coli and S. aureus at 1% dilution. The oil was also active against Plasmodium falciparum in micromolar concentrations.
Manenzhe
Nkhumeleni Jeoffrey
NJ
Department of Chemistry, University of Venda for Science and Technology, Private Bag X5050, Thohoyandou 0950, South Africa.
Potgieter
Natasha
N
van Ree
Teunis
T
D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D032411:Lippia / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry; D010963:Plasmodium falciparum / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D009822:Oils, Volatile