title: Functional outcome in patients with critical illness polyneuropathy.
abstract: OBJECTIVE
  To evaluate the functional outcome of intensive care patients with critical illness polyneuropathy (CIP), 6 and 12 months after the onset.
  
  
  METHODS
  
  
  
  METHODS
  A prospective observational cohort study and a cross-sectional study.
  
  
  METHODS
  University hospital in the Netherlands.
  
  
  METHODS
  Eight consecutive intensive care patients with CIP for the prospective study and eight patients diagnosed with CIP in the past 6 months for the cross-sectional study.
  
  
  METHODS
  Functional outcome regarding body functions and structure, activities, participation and perceived quality of life.
  
  
  RESULTS
  Nine patients (56%) died within one year. Functional outcome, participation and subjective health status in survivors varied widely at 6 and 12 months. After 12 months, physical functioning was improved in all patients. However activities related to mobility outdoors, autonomy, participation and quality of life were restricted in most patients.
  
  
  CONCLUSIONS
  The majority of survivors have persistent functional disabilities in activities, reduced quality of life and restrictions in autonomy and participation one year after the onset of CIP. Prolonged rehabilitation treatment is necessary for an increasing number of intensive care patients who develop CIP, in order to reduce handicaps and achieve optimal autonomy and social participation.
authors.affiliation: Department of Rehabilitation, Academic Medical Center, University of Amsterdam, The Netherlands.
authors.forename: Marike
authors.initials: M
authors.lastname: van der Schaaf
authors.forename: Anita
authors.initials: A
authors.lastname: Beelen
authors.forename: Rien
authors.initials: R
authors.lastname: de Vos
mesh_terms: D000328:Adult; D000368:Aged; D015331:Cohort Studies; D003422:Critical Care / Q000379:methods*; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006304:Health Status; D006785:Hospitals, University; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000150:complications; D009426:Netherlands; D017063:Outcome Assessment, Health Care; D018579:Patient Selection; D011115:Polyneuropathies / Q000209:etiology / Q000534:rehabilitation* / Q000628:therapy*; D011446:Prospective Studies; D011788:Quality of Life; D020127:Recovery of Function; D012121:Respiration, Artificial / Q000009:adverse effects; D018805:Sepsis / Q000150:complications; D011795:Surveys and Questionnaires