title: Liver transplantation for a hilar inflammatory myofibroblastic tumor.
abstract: A 7-yr-old boy presented with obstructive jaundice secondary to an inflammatory myofibroblastic tumor centered on the hepatic hilum and extending into the liver. The tumor was further complicated by portal vein phlebitis and occlusion. Attempted resection of the tumor with portal vein reconstruction and bilioenteric drainage was unsuccessful and he required urgent orthotopic liver transplantation. In contrast to more peripheral inflammatory myofibroblastic tumors in the liver, hilar lesions are locally aggressive, causing occlusive portal phlebitis and biliary obstruction. Successful management may include the need for liver transplantation.
authors.affiliation: Children's Liver and GI Unit, Gledhow Wing, St James's University Hospital, Leeds LS9 7TF, UK.
authors.forename: D
authors.initials: D
authors.lastname: Dasgupta
authors.forename: A
authors.initials: A
authors.lastname: Guthrie
authors.forename: P
authors.initials: P
authors.lastname: McClean
authors.forename: S
authors.initials: S
authors.lastname: Davison
authors.forename: J
authors.initials: J
authors.lastname: Luntley
authors.forename: S
authors.initials: S
authors.lastname: Rajwal
authors.forename: J P A
authors.initials: JP
authors.lastname: Lodge
authors.forename: K R
authors.initials: KR
authors.lastname: Prasad
authors.forename: J I
authors.initials: JI
authors.lastname: Wyatt
authors.forename: M D
authors.initials: MD
authors.lastname: Stringer
mesh_terms: D002648:Child; D006801:Humans; D007249:Inflammation / Q000473:pathology; D041781:Jaundice, Obstructive / Q000209:etiology; D008099:Liver / Q000473:pathology / Q000601:surgery; D008113:Liver Neoplasms / Q000150:complications / Q000601:surgery*; D016031:Liver Transplantation; D008279:Magnetic Resonance Imaging; D008297:Male; D009379:Neoplasms, Muscle Tissue / Q000150:complications / Q000473:pathology / Q000601:surgery*; D011169:Portal Vein / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography; D016896:Treatment Outcome