title: Histochemical characterization of skeletal muscles in rats with photochemically-induced stroke.
abstract: OBJECTIVE
  The aim of this study was to assess skeletal muscle showing a complete functional recovery after induction of pan-necrotic lesions in the right sensorimotor cortex in rats.
  
  
  METHODS
  A focal lesion of the right sensorimotor cortex was induced photochemically. Rats were divided into three groups; the sham-operated group (CON), Stroke (RB) and Stroke plus severed right sciatic nerve (RBD).
  
  
  RESULTS
  All RB rats showed complete functional recovery in the beam-walking test within 10 days. The score of CON rats was 7 for 21 days. The wet weight of the soleus muscle (SOL) only in the RB and RBD was significantly greater than in the CON. The cross-sectional area of type I fibres was increased in SOL.
  
  
  CONCLUSIONS
  It was concluded that the functional recovery was mainly due to increased wet weight and cross-sectional area of type I SOL fibres, which probably reflected the functional reorganization and neuromodulation in the non-damaged contralateral sensorimotor cortex and ipsilateral sensorimotor cortex lateral to the lesion identified in a previous study.
authors.affiliation: Department of Rehabilitation Medicine, Jikei Medical School of Medicine, 3-25-8 Nishishinbashi Minato-ku, Tokyo, 105-8461, Japan. abo@jikei.ac.jp
authors.forename: Masahiro
authors.initials: M
authors.lastname: Abo
authors.forename: Satoshi
authors.initials: S
authors.lastname: Miyano
authors.forename: Sang Soo
authors.initials: SS
authors.lastname: Eun
authors.forename: Hideki
authors.initials: H
authors.lastname: Yamauchi
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology; D005260:Female; D006614:Hindlimb; D008027:Light; D023421:Models, Animal; D009043:Motor Activity; D009044:Motor Cortex; D018482:Muscle, Skeletal / Q000201:enzymology* / Q000473:pathology; D009218:Myosins / Q000032:analysis*; D051381:Rats; D011916:Rats, Inbred F344; D020127:Recovery of Function; D012395:Rose Bengal; D013003:Somatosensory Cortex; D020521:Stroke / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology
chemical_list: D012395:Rose Bengal; D009218:Myosins