title: Phosphoinositides: older than we first thought?
abstract: Despite nearly 50 years of study, it is good to see that phosphoinositides are still capable of springing the odd surprise. Signaling by the second messenger phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P(3)) was thought to be absent in yeast, but a recent paper now describes the presence of PtdIns(3,4,5)P(3) in Schizosaccharomyces pombe.
authors.affiliation: Department of Biochemistry and Molecular Biology, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK. f.cooke@ucl.ac.uk
authors.forename: Frank T
authors.initials: FT
authors.lastname: Cooke
mesh_terms: D019143:Evolution, Molecular; D008954:Models, Biological; D018129:Phosphatidylinositol Phosphates / Q000378:metabolism*; D012568:Schizosaccharomyces / Q000378:metabolism* / Q000502:physiology; D015290:Second Messenger Systems; D015398:Signal Transduction; D013045:Species Specificity
chemical_list: D018129:Phosphatidylinositol Phosphates; C060974:phosphatidylinositol 3,4,5-triphosphate