title: Chronological changes of serum chromium levels after modern metal-on-metal total hip arthroplasty.
abstract: We determined changes in serum chromium concentration every 6 months up to 3 years after implantation in 44 patients (mean age 63 (49-79) years, 35 women) who underwent modern metal-on-metal total hip arthroplasty (Metasul). The serum chromium levels increased between the first and second year after implantation (1 year: 1.05 (SD 0.76) microg/L, 2 years: 1.46 (SD 0.91) microg/L). A small increase was observed during the third year (1.61 (SD 1.31) microg/L). The clinical relevance of this finding is uncertain and should be determined in long-term studies on a large scale.
authors.affiliation: Departmnt of Orthopaedic Surgery, Juntendo University School of Medicine, Hongo, Tokyo, Japan. maeza@med.juntendo.ac.jp
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Maezawa
authors.forename: Masahiko
authors.initials: M
authors.lastname: Nozawa
authors.forename: Keiji
authors.initials: K
authors.lastname: Matsuda
authors.forename: Motoo
authors.initials: M
authors.lastname: Yasuma
authors.forename: Kaoru
authors.initials: K
authors.lastname: Mori
authors.forename: Fumiyo
authors.initials: F
authors.lastname: Enomoto
authors.forename: Seiki
authors.initials: S
authors.lastname: Ogawa
authors.forename: Katsuo
authors.initials: K
authors.lastname: Shitoto
authors.forename: Hisashi
authors.initials: H
authors.lastname: Kurosawa
mesh_terms: D000368:Aged; D000497:Alloys; D019644:Arthroplasty, Replacement, Hip; D002857:Chromium / Q000097:blood*; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D013997:Time Factors
chemical_list: D000497:Alloys; D002857:Chromium