Post-infectious acute renal failure due to calciphylaxis--when processes go the wrong way round.
Calciphylaxis is a rare life threatening disorder of small- and medium-sized vessel calcification that leads to cutaneous necrosis. While its pathogenesis is uncertain, nearly all cases have been described in patients with end-stage renal disease (ESRD) on dialysis or following renal transplantation which is why the lesion has also been referred to as calcific uremic arteriolopathy. We describe a patient with alcoholic cirrhosis and normal renal function who developed calciphylaxis. Due to infected cutaneous lesions, he developed an acute post-infectious glomerulonephritis with extra capillary proliferation.
Almirall
Jaume
J
Service of Nephrology, Consorci Hospitalari Parc Taulí, Sabadell, Barcelona, Spain. jalmirall@cspt.es
Pobo
Angel
A
Luelmo
Jesús
J
Berna
Lluis
L
D058186:Acute Kidney Injury / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D001707:Biopsy, Needle; D002115:Calciphylaxis / Q000150:complications* / Q000000981:diagnostic imaging*; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007677:Kidney Function Tests; D007871:Leg Ulcer / Q000150:complications* / Q000175:diagnosis; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D018570:Risk Assessment; D012720:Severity of Illness Index
D007166:Immunosuppressive Agents