Possible therapeutic role of vitamin D3 in aggressive fibromatosis.
Desmoids, also known as aggressive fibromatoses, are locally invasive tumors that are intermediate in their biological behavior that lies between benign fibrous proliferations and low-grade fibrosarcomas. In this report, we present a case of a young female patient with a huge tumoral mass located in the right shoulder region that recurred after total resection and was resistant to radio-chemo-hormonal therapy. Eventually, she responded to 1,25-(OH)(2)-vitamin D(3) treatment.
Ferah
Yildiz
Y
Department of Radiation Oncology, Hacettepe University Faculty of Medicine, 06100 Ankara, Turkey. fyildiz@hacettepe.edu.tr
Ayse
Kars
K
Mustafa
Cengiz
C
Ugur
Selek
S
Murat
Gurkaynak
G
Lale
Atahan I
AI
D000328:Adult; D002762:Cholecalciferol / Q000627:therapeutic use*; D005260:Female; D018222:Desmoid Tumors / Q000175:diagnosis / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D011879:Radiotherapy Dosage; D012782:Shoulder
D002762:Cholecalciferol