[A case of a patient with solitary prostate metastasis of the colorectal carcinoma three years after abdominoperineal amputation of the rectum].
OBJECTIVE
The aim of this study is to present a case-review of a patient with an extremely rare finding of a solitary metastasis of the colorectal carcinoma in his prostate.


METHODS
A Case-Review.


RESULTS
The study describes a case of a 42-year-old patient who underwent abdominoperineal amputation for the rectal carcinoma pT3 N1 M0 with complementary actinotherapy and chemotherapy. Three years after his rectum amputation, a CT scan disclosed a hypodense focus in his prostate of unknown origin. Elevation of the CEA was found upon laboratory examination, other tumor markers including the PSA were not abnormal. The positron emission tomography (PET) did not disclose other distant foci. The patient was administered 4 courses of chemotherapy with, basically, no signs of regression in the prostate foci. Biopsy from the suspicious focus was conducted transperitoneally, followed by its histological examination which confirmed cribriform adenocarcinoma. Our team decided on salvage cystoprostatectomy, securing urine derivation by the ilium conduit. 6 months later, the CT examination showed a massive local relapse and two metastatic foci in the liver, further oncological therapy was not indicated. The patient died 7 moths after the radical cystoprostatectomy.


CONCLUSIONS
This case-review points out a possibility of metastatic prostate affections connected to the colorectal carcinoma disorder, as well as its treatment procedures.
Pesl
M
M
Urologická klinika VFN a 1. LF UK, Praha. pesl_m@hotmail.com
Safarík
L
L
Dusková
J
J
Soukup
V
V
Dundr
P
P
Donociková
B
B
Dvorácek
J
J
D000230:Adenocarcinoma / Q000556:secondary* / Q000601:surgery; D000328:Adult; D015179:Colorectal Neoplasms / Q000473:pathology*; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000556:secondary* / Q000601:surgery; D012007:Rectum / Q000601:surgery*
Prípad pacienta se solitární metastázou kolorektálního karcinomu v prostatĕ tri roky po abdominoperineální amputaci rekta.