Changes in quality of life and self-perspective related to surgery in patients with temporal lobe epilepsy.
OBJECTIVE
To evaluate changes in intractable epilepsy patients in terms of quality of life, depression, anxiety, stigma, and impact of epilepsy before and after surgery.


METHODS
Twenty patients with intractable temporal lobe epilepsy who were waiting for surgery (pre-SAH group) and 21 patients who had already undergone surgery (post-SAH group) were studied. All patients received SF-36, Beck Depression Inventory, State-Trait Anxiety Inventory, stigma and impact of epilepsy inventories, and a form asking their own perspectives about epilepsy and surgery.


RESULTS
Post-SAH group scored higher on all subscales of SF-36, with only RE scores being significantly better (t=-1.98, P=.05). Although depression, anxiety, and stigma scores were higher in pre-SAH group, only impact of epilepsy scores were significantly higher in pre-SAH group (t=-2.951, P=.005). Seizure frequency and comorbidity had significant effects on QOL where amount of AEDs and QOL were negatively related (r=-0.318, P<0.05). Both groups stated lack of independence and social activities as the main concern (48.8%) and recovery from epilepsy as the most important expectation from surgery (85.4%). Post-surgical group mentioned the difference in their life after surgery as independence and increase in social activities (47.6%).


CONCLUSIONS
QOL of patients after surgery was found to be better than before surgery. Results also revealed that seizure frequency, comorbidity, and anti-epileptic medication affected health related QOL negatively. Impact of epilepsy levels was found to be higher among the pre-SAH patients. Finally, independence seemed to be the most important concern and gain for Turkish epilepsy patients.
Aydemir
Nuran
N
Istanbul University, Istanbul, Turkey. aydemirn@istanbul.edu.tr <aydemirn@istanbul.edu.tr>
Ozkara
Cigdem
C
Canbeyli
Reşit
R
Tekcan
Ali
A
D000328:Adult; D000679:Amygdala / Q000601:surgery; D000927:Anticonvulsants / Q000008:administration & dosage / Q000627:therapeutic use; D001007:Anxiety / Q000209:etiology / Q000523:psychology; D015897:Comorbidity; D003430:Cross-Sectional Studies; D004351:Drug Resistance; D004833:Epilepsy, Temporal Lobe / Q000150:complications / Q000523:psychology* / Q000601:surgery*; D005260:Female; D006262:Health; D006624:Hippocampus / Q000601:surgery; D006801:Humans; D008297:Male; D019635:Neurosurgical Procedures; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life; D012640:Seizures / Q000453:epidemiology; D016896:Treatment Outcome; D014421:Turkey
D000927:Anticonvulsants