Tetrafibricin: synthesis of the C1-C13, C15-C25, and C27-C40 fragments.
[structure: see text] A sequence of chemoselective cross-metathesis reactions and enantioselective allyltitanations of aldehydes has been used to prepare the C1-C13, C15-C26, and C27-C40 fragments of tetrafibricin.
BouzBouz
Samir
S
Laboratoire de Chimie Organique associé au CNRS, ESPCI, 10 rue Vauquelin, 75231 Paris Cedex 05, France. samir.bouzbouz@espci.fr
Cossy
Janine
J
D000447:Aldehydes / Q000737:chemistry; D002384:Catalysis; D007202:Indicators and Reagents; D018942:Macrolides / Q000138:chemical synthesis*; D015394:Molecular Structure; D013237:Stereoisomerism; D013302:Streptomyces / Q000737:chemistry
D000447:Aldehydes; D007202:Indicators and Reagents; D018942:Macrolides; C082780:tetrafibricin