title: Preparation of beta-keto esters and beta-diketones by C-acylation/deacetylation of acetoacetic esters and acetonyl ketones with 1-acylbenzotriazoles.
abstract: Acyl-, aroyl-, and heteroaroyl-acetic esters 6a-f and 8a-l are prepared by reactions of 1-acylbenzotriazoles 1a-k with acetoacetic esters 5 or 7a,b in the presence of sodium hydride followed by regioselective deacetylation. Similar C-acylation/deacetylation of acetylacetone and benzoylacetone affords beta-diketones 10a-d and 13a-c, respectively.
authors.affiliation: Center for Heterocyclic Compounds, University of Florida, Department of Chemistry, Gainesville, Florida 32611-7200, USA. katritzky@chem.ufl.edu
authors.forename: Alan R
authors.initials: AR
authors.lastname: Katritzky
authors.forename: Zuoquan
authors.initials: Z
authors.lastname: Wang
authors.forename: Mingyi
authors.initials: M
authors.lastname: Wang
authors.forename: Chavon R
authors.initials: CR
authors.lastname: Wilkerson
authors.forename: C Dennis
authors.initials: CD
authors.lastname: Hall
authors.forename: Novruz G
authors.initials: NG
authors.lastname: Akhmedov