Ionic and covalent copper(II)-based catalysts for Michael additions. The mechanism.
Cu(SbF6)2-AdamBox and copper(II) bis-(5-tert-butylsalicylaldehydate) catalyze the Michael addition in neutral media. Mechanistic studies, based on UV-vis, IR, and electrospray ionization mass spectrometry (ESI-MS), suggest that copper enolates of the beta-dicarbonyl formed in situ are the active nucleophilic species.
Comelles
Josep
J
Department of Chemistry, Universitat Autonoma de Barcelona, Cerdanyola, 08193-Barcelona, Spain.
Moreno-Mañas
Marcial
M
Pérez
Elisabet
E
Roglans
Anna
A
Sebastián
Rosa M
RM
Vallribera
Adelina
A