title: Use of oral supplements in malnourished elderly patients living in the community: a pharmaco-economic study.
abstract: OBJECTIVE
  Inadequate nutritional support in elderly patients is likely to be responsible for increased morbidity and increased associated costs. Conversely prescribing oral supplements to ensure sufficient protein and energy intake should be beneficial. Even though this claim makes sense there is a lack of objective data to support the evidence. The objective of the present study was to assess the cost of malnutrition and related comorbidities among elderly patients living in the community and to determine the impact of nutritional support practice on these outcomes.
  
  
  METHODS
  Observational, prospective, longitudinal, cohort study with a 12 months follow-up conducted with 90 general practitioners in France. Two groups of physicians were selected based on historical prescribing practice: group 1 with rare and group 2 with frequent prescription of oral nutrition supplements. The resulting study population was 378 elderly malnourished patients aged over 70, living in the community, either at home or in institutions. Nutritional status at baseline was determined using the Mini Nutritional Assessment (MNA) scale. Main outcome measures were nutritional status, malnutrition-related comorbidities and medical care consumption.
  
  
  RESULTS
  Populations in the two groups of patients were balanced for age, gender, weight and body mass index but differed significantly in terms of housing status (P < 0.005) and nutritional status (P < 0.001). After adjustment for baseline characteristics, MNA improved within both groups over time but improvement was significantly higher in group 2 than in group 1 (P < 0.01). The adjusted cost per patient of hospital care (EUR -551), nursing care (EUR -145) and other medical care was significantly reduced in group 2 as compared to group 1, with cost savings of EUR -723 per patient (90% CI: EUR -1.444 to EUR -43). Including the costs related to nutritional products, the total cost savings per patient attributable to nutrition support were EUR -195 (90% CI: EUR -929 to EUR +478).
  
  
  CONCLUSIONS
  Appropriate nutrition support can address the problem of malnutrition among elderly individuals living in the community and may contribute to reduce the costs of health care.
authors.affiliation: Nestlé Clinical Nutrition, Noisiel, France.
authors.forename: F
authors.initials: F
authors.lastname: Arnaud-Battandier
authors.forename: D
authors.initials: D
authors.lastname: Malvy
authors.forename: C
authors.initials: C
authors.lastname: Jeandel
authors.forename: C
authors.initials: C
authors.lastname: Schmitt
authors.forename: P
authors.initials: P
authors.lastname: Aussage
authors.forename: B
authors.initials: B
authors.lastname: Beaufrère
authors.forename: L
authors.initials: L
authors.lastname: Cynober
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D015897:Comorbidity; D019587:Dietary Supplements; D005260:Female; D005526:Food, Formulated; D015577:Geriatric Assessment; D017048:Health Care Costs; D006305:Health Status Indicators; D006760:Hospitalization / Q000191:economics; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D015596:Nutrition Assessment; D009752:Nutritional Status; D011446:Prospective Studies; D011502:Protein-Energy Malnutrition / Q000150:complications / Q000191:economics / Q000628:therapy; D016896:Treatment Outcome