title: Spontaneous regression of recurrent squamous cell carcinoma of the tongue.
abstract: A 73-year-old man presented with well-differentiated squamous cell carcinoma of the tongue (T3N0N0). After the completion of external beam radiotherapy (32 Gy) and oral tegafur-uracil (UFT) administration, the tumor had clinically disappeared. Two years later, a recurrent lesion was confirmed histologically. Without any specific therapy, the tumor gradually and spontaneously regressed, from 4 months after the recurrence was diagnosed, and it had completely disappeared both clinically and by computed tomography imaging at 1 year and 4 months after recurrence. There was no evidence suggesting regrowth of the disease in the patient at 3 years and 7 months after the histological confirmation of tumor recurrence.
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Fukuoka, Japan. r-oya@clnc.uoeh-u.ac.jp
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Oya
authors.forename: Kunio
authors.initials: K
authors.lastname: Ikemura
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy; D004338:Drug Combinations; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local; D009365:Neoplasm Regression, Spontaneous; D005641:Tegafur / Q000627:therapeutic use; D014062:Tongue Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy; D014498:Uracil / Q000627:therapeutic use
chemical_list: D004338:Drug Combinations; C096910:UFT(R) drug; D005641:Tegafur; D014498:Uracil