Too much lactate or too little liver?
We describe a 67-year-old woman with cholangiocarcinoma who was scheduled for cholecystectomy, trisegmentectomy, bile duct resection, and regional lymphadenectomy. Her case was complicated by hyperlactatemia, sepsis, and multiorgan failure. The discussion reviews the possible causes of the hyperlactatemia and reviews measures that could be used to reduce this risk.
Marko
Petar
P
Department of Anesthesiology, University of Florida College of Medicine, Gainesville, FL 32610-0254, USA.
Gabrielli
Andrea
A
Caruso
Lawrence J
LJ
D000140:Acidosis, Lactic / Q000209:etiology*; D000255:Adenosine Triphosphate / Q000378:metabolism; D000368:Aged; D005260:Female; D006440:Hemofiltration; D006801:Humans; D019344:Lactic Acid / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008107:Liver Diseases / Q000378:metabolism*; D009243:NAD / Q000378:metabolism
D009243:NAD; D019344:Lactic Acid; D000255:Adenosine Triphosphate