Should we be using cimetidine to premedicate patients receiving docetaxel or paclitaxel?
Clouse
Thomas
T
Geisler
John P
JP
Manahan
Kelly J
KJ
Gudenkauf
Thomas J
TJ
Linnemeier
Georgiann
G
Wiemann
Michael C
MC
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000493:pharmacokinetics / Q000494:pharmacology*; D016190:Carboplatin / Q000008:administration & dosage / Q000493:pharmacokinetics; D002927:Cimetidine / Q000008:administration & dosage / Q000494:pharmacology*; D002945:Cisplatin / Q000008:administration & dosage / Q000493:pharmacokinetics; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D000077143:Docetaxel; D004357:Drug Synergism; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000201:enzymology; D017239:Paclitaxel / Q000008:administration & dosage / Q000493:pharmacokinetics; D043823:Taxoids / Q000008:administration & dosage / Q000493:pharmacokinetics
D043823:Taxoids; D000077143:Docetaxel; D002927:Cimetidine; D003577:Cytochrome P-450 Enzyme System; D016190:Carboplatin; C104464:CYP3A protein, human; D051544:Cytochrome P-450 CYP3A; D017239:Paclitaxel; D002945:Cisplatin