The open reading frame present in the nrdEF cluster of Corynebacterium ammoniagenes is a transcriptional regulator belonging to the GntR family.
In this work we have identified the cagntR gene, present between the nrdE and nrdF genes of Corynebacterium ammoniagenes, as a transcriptional regulator belonging to the GntR family. This gene encodes a transcriptional factor actively transcribed in the opposite direction relative to the nrdHIEF operon. It is expressed in a cell-culture-dependent fashion and, although the members of this family have been reported to regulate transcription of genes found within their vicinity, we have shown that cagntR is not involved in the transcriptional regulation of either nrdE or nrdF. The role of this regulator, however, remains unknown.
Torrents
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E
Institut de Biotecnologia i de Biomedicina and Departament de Genètica i de Microbiologia, Grup de Genètica Molecular Bacteriana, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain.
Roca
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I
Gibert
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I
D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics; D002874:Chromosome Mapping; D003352:Corynebacterium / Q000235:genetics*; D015870:Gene Expression; D005798:Genes, Bacterial; D019077:Helix-Turn-Helix Motifs; D008969:Molecular Sequence Data; D005810:Multigene Family; D016366:Open Reading Frames; D010802:Phylogeny; D017386:Sequence Homology, Amino Acid; D014157:Transcription Factors / Q000737:chemistry / Q000235:genetics
D001426:Bacterial Proteins; D014157:Transcription Factors