title: Nutritional requirements of Allisonella histaminiformans, a ruminal bacterium that decarboxylates histidine and produces histamine.
abstract: Histamine is an inflammatory agent that contributes to bovine laminitis. Cattle fed silage-containing rations often have large populations of Allisonella histaminiformans, but this obligate histidine-decarboxylating bacterium could not be isolated from cattle fed timothy hay. The growth of A. histaminiformans was stimulated by yeast extract, protein hydrolysates, and water-soluble extracts of alfalfa or corn silage. Extracts of alfalfa were more potent than corn silage. Because growth and histamine production were not stimulated by Casamino Acids or a mixture of purified amino acids, it appeared that A. histaminiformans requires peptides. The idea that A. histaminiformans requires peptides is consistent with the observation that alfalfa silages often have a large amount of peptide nitrogen.
authors.affiliation: Department of Microbiology, Cornell University, Ithaca, NY 14853, USA.
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Garner
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Gronquist
authors.forename: James B
authors.initials: JB
authors.lastname: Russell
mesh_terms: D000821:Animal Feed / Q000382:microbiology; D000818:Animals; D002417:Cattle; D003470:Culture Media; D006632:Histamine / Q000096:biosynthesis*; D006639:Histidine / Q000378:metabolism*; D006640:Histidine Decarboxylase / Q000378:metabolism*; D000455:Medicago sativa / Q000378:metabolism; D012417:Rumen / Q000382:microbiology*; D012820:Silage / Q000382:microbiology*; D045854:Veillonellaceae / Q000201:enzymology / Q000378:metabolism*; D003313:Zea mays / Q000378:metabolism
chemical_list: D003470:Culture Media; D006639:Histidine; D006632:Histamine; D006640:Histidine Decarboxylase