title: Too much lactate or too little liver?
abstract: We describe a 67-year-old woman with cholangiocarcinoma who was scheduled for cholecystectomy, trisegmentectomy, bile duct resection, and regional lymphadenectomy. Her case was complicated by hyperlactatemia, sepsis, and multiorgan failure. The discussion reviews the possible causes of the hyperlactatemia and reviews measures that could be used to reduce this risk.
authors.affiliation: Department of Anesthesiology, University of Florida College of Medicine, Gainesville, FL 32610-0254, USA.
authors.forename: Petar
authors.initials: P
authors.lastname: Marko
authors.forename: Andrea
authors.initials: A
authors.lastname: Gabrielli
authors.forename: Lawrence J
authors.initials: LJ
authors.lastname: Caruso
mesh_terms: D000140:Acidosis, Lactic / Q000209:etiology*; D000255:Adenosine Triphosphate / Q000378:metabolism; D000368:Aged; D005260:Female; D006440:Hemofiltration; D006801:Humans; D019344:Lactic Acid / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008107:Liver Diseases / Q000378:metabolism*; D009243:NAD / Q000378:metabolism
chemical_list: D009243:NAD; D019344:Lactic Acid; D000255:Adenosine Triphosphate