title: [Chronic hepatitis and cirrhosis caused by C virus before and after liver transplantation. Report of one case].
abstract: We report a girl with a chronic hepatitis caused by C virus diagnosed at the age of nine, unsuccessfully treated with interferon and ribavirine. Two years later, she was subjected to a liver transplantation. She maintained elevated viral loads with a normal pathological study of the liver until 22 months after transplantation. She was treated again with combined antiviral therapy, for 6 months, without response and experienced a progressive deterioration liver function, dying three years after transplantation.
authors.affiliation: Unidad de Gastroenterología, Hospital Roberto del Río. silvialegria@entelchile.net
authors.forename: Sylvia
authors.initials: S
authors.lastname: Alegría
authors.forename: Erwin
authors.initials: E
authors.lastname: Buckel
authors.forename: Mario
authors.initials: M
authors.lastname: Ferrario
authors.forename: Sergio
authors.initials: S
authors.lastname: Ceresa
authors.forename: Gladys
authors.initials: G
authors.lastname: Smok
authors.forename: Javier
authors.initials: J
authors.lastname: Brahm
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D004359:Drug Therapy, Combination; D017809:Fatal Outcome; D005260:Female; D019698:Hepatitis C, Chronic / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D008103:Liver Cirrhosis / Q000188:drug therapy / Q000473:pathology / Q000821:virology*; D016031:Liver Transplantation; D012254:Ribavirin / Q000627:therapeutic use; D019562:Viral Load
chemical_list: D000998:Antiviral Agents; D012254:Ribavirin; D007372:Interferons
vernacular_title: Hepatitis crónica y cirrosis por virus C pre y post trasplante hepático en una niña de 9 años.