title: Lichtenstein repair of inguinal hernia with Surgisis inguinal hernia matrix soft-tissue graft in immunodepressed patients.
abstract: While polypropylene mesh remains the preferred prosthesis material for hernioplasties, there are some problems with infections, intestinal obstruction and fistulization, and migration particularly in immunodepressed patients. A new degradable and reabsorbable material, the porcine small intestinal submucosa (Surgisis) has been developed for hernia repairs in humans. This prospective study evaluated the safety and efficacy of Lichtenstein hernioplasty using the Surgisis inguinal hernia matrix soft-tissue graft as a mesh in ten immunodepressed subjects. Six subjects were HIV-positive in the immunodepressive phase, and the other four had undergone transplantation (three kidney, one liver). There were no intraoperative or postoperative complications, recurrences, or wound infections. Thus Lichtenstein's hernioplasty using the Surgisis inguinal hernia matrix soft-tissue graft in immunodepressed patients promises safety and efficacy.
authors.affiliation: Emergency Surgery DPT, St. Orsola-Malpighi University Hospital, Via Massarenti 9 40138, Bologna, Italy. fcatena@orsola-malpighi.med.unibo.it
authors.forename: F
authors.initials: F
authors.lastname: Catena
authors.forename: L
authors.initials: L
authors.lastname: Ansaloni
authors.forename: A
authors.initials: A
authors.lastname: Leone
authors.forename: A
authors.initials: A
authors.lastname: De Cataldis
authors.forename: S
authors.initials: S
authors.lastname: Gagliardi
authors.forename: F
authors.initials: F
authors.lastname: Gazzotti
authors.forename: S
authors.initials: S
authors.lastname: Peruzzi
authors.forename: S
authors.initials: S
authors.lastname: Agrusti
authors.forename: L
authors.initials: L
authors.lastname: D'Alessandro
authors.forename: M
authors.initials: M
authors.lastname: Taffurelli
mesh_terms: D020341:Absorbable Implants; D005109:Extracellular Matrix; D006678:HIV / Q000276:immunology; D006679:HIV Seropositivity / Q000150:complications / Q000276:immunology*; D006552:Hernia, Inguinal / Q000150:complications / Q000601:surgery*; D006801:Humans; D016867:Immunocompromised Host; D011446:Prospective Studies; D011474:Prosthesis Design; D019919:Prosthesis Implantation / Q000295:instrumentation*; D012449:Safety; D013526:Surgical Mesh; D016896:Treatment Outcome