Highly antimalaria-active artemisinin derivatives: biological activity does not correlate with chemical reactivity.
Haynes
Richard K
RK
Department of Chemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, P.R. China. haynes@ust.hk
Ho
Wing-Yan
WY
Chan
Ho-Wai
HW
Fugmann
Burkhard
B
Stetter
Jörg
J
Croft
Simon L
SL
Vivas
Livia
L
Peters
Wallace
W
Robinson
Brian L
BL
D000818:Animals; D000962:Antimalarials / Q000378:metabolism / Q000494:pharmacology*; D037621:Artemisinins / Q000378:metabolism / Q000494:pharmacology*; D005609:Free Radicals / Q000737:chemistry; D051379:Mice; D008968:Molecular Conformation; D021261:Parasitic Sensitivity Tests; D012717:Sesquiterpenes / Q000378:metabolism / Q000494:pharmacology; D013329:Structure-Activity Relationship
D000962:Antimalarials; D037621:Artemisinins; D005609:Free Radicals; D012717:Sesquiterpenes; C039060:artenimol