Complete nucleotide sequences of ALV-related endogenous retroviruses available from the draft chicken genome sequence.
Complete nucleotide sequences of chicken endogenous retroviruses belonging to E33/E51 and EAV-0 groups have been analysed on the basis of the recently available draft genome sequence of red jungle fowl (Gallus gallus), the progenitor of domestic chicken (G.g. domesticus). It was shown that all these proviruses have deletions in the SU-coding domain of the env gene, involved in receptor recognition, whereas gag and pol genes appear to be intact. Phylogenetic analysis demonstrated that E33/E51 and EAV-0 groups are related to the ALV genus. An analysis of expression using chicken EST databases showed that these proviruses are transcriptionally active.
Borisenko
L
L
Department of Molecular Oncogenetics, Institute of Molecular Biology and Genetics, Ukrainian Academy of Sciences, Kiev, Ukraine.
Rynditch
A V
AV
D001355:Alpharetrovirus / Q000145:classification / Q000235:genetics*; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002645:Chickens / Q000235:genetics*; D019295:Computational Biology; D020077:Endogenous Retroviruses / Q000145:classification / Q000235:genetics*; D016678:Genome; D008969:Molecular Sequence Data; D010802:Phylogeny