NMR Wool Tube: a novel method for NMR solution analysis of derivatized glass surfaces.
Glass wool was placed within an NMR tube as a solid support for the covalent attachment of a molecule to allow for a simple one-dimensional 1H FT NMR solution analysis. This novel procedure avoids the use of expensive sample tubes or platforms, as required for magic angle or fast spinning, exotic pulse sequences, isotopic labeling or the use of a large number of scans to provide the ability to analyze the structure, mobility, ligand binding, and solvent interactions of the surface bound molecule.
Cholewa
Olivia Maria
OM
School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705-2222, USA. ocholewa@students.wisc.edu
D005898:Glass; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D013499:Surface Properties