Production of 166Ho through 164Dy(n, gamma)165Dy(n, gamma)166Dy(beta-)166Ho and separation of 166Ho.
After irradiation with thermal neutrons 164Dy produces 166Ho through the nuclear reaction: 164Dy(n, gamma) 165Dy(n, gamma) 166Dy beta- --> 166Ho. 166Ho has been separated from the bulk dysprosium target with the help of HPLC using Aminex A7 ion exchanger resin and alpha-hydroxyisobutyric acid (alpha-HIBA) as the mobile phase. The separation was quantitative and without any contamination from the dysprosium target. Method has also been developed to produce holmium free of alpha-HIBA ligands. Attempts have been made to produce no-carrier-added recoiled 166Ho and 165Dy in water.
Lahiri
Susanta
S
Chemical Sciences Division, Saha Institute of Nuclear Physics, 1/AF Bidhannagar, Kolkata 700 064, India. slahiri@nuc.saha.ernet.in
Volkers
Kees J
KJ
Wierczinski
Birgit
B
D005591:Chemical Fractionation / Q000379:methods*; D002852:Chromatography, Ion Exchange / Q000379:methods*; D006695:Holmium / Q000737:chemistry* / Q000302:isolation & purification*; D006885:Hydroxybutyrates / Q000737:chemistry; D007475:Ion Exchange Resins / Q000737:chemistry; D007553:Isotope Labeling / Q000379:methods*; D011868:Radioisotopes / Q000737:chemistry* / Q000302:isolation & purification*; D019275:Radiopharmaceuticals / Q000138:chemical synthesis / Q000302:isolation & purification
D006885:Hydroxybutyrates; D007475:Ion Exchange Resins; D011868:Radioisotopes; D019275:Radiopharmaceuticals; C008039:2-hydroxyisobutyric acid; D006695:Holmium