title: Carotid stenosis and coronary artery disease in the elderly: the vascular surgeon's point of view.
abstract: Surgical prevention of stroke is justified only when the perioperative morbidity and mortality rates are very low. Therefore, an accurate cardiac evaluation is essential for patients with a vascular disease like carotid stenosis, to reduce the surgical risk and improve prognosis. The aim of our retrospective study was to characterize subgroups of patients with high cardiac risk. From 1986 to 1993 at the Vascular Surgery Unit of the Department of Surgery and Surgical Emergencies at the University of Perugia, 857 carotid endarterectomies were performed on 739 patients. The stroke/death rate, at 30 days after surgery, was 2.16% per patient and 1.86% per procedure; cardiac mortality was 0. However, during follow-up 58 patients died: 55% of these deaths could be attributed to cardiac disease. No statistically significant differences emerged in cardiac mortality of patients with a positive history of cerebral vascular accident with respect to asymptomatics, neither among patients with carotid stenosis associated with complete contralateral occlusion nor among those without. Our group of patients had a 76% survival rate at 7 years after surgery, which is different from that reported by other studies. This may be due to some bias associated with the preoperative selection of the patients and the retrospective nature of our study. Nevertheless, in patients with carotid stenosis, the most important cause of death is cardiac ischemia, therefore a rigorous preoperative selection is mandatory particularly in elderly asymptomatic patients.
authors.affiliation: Vascular Surgery Unit, Department of Surgery and Surgical Emergencies, University of Perugia, Policlinico Monteluce, 06122 Perugia, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Cao
authors.forename: F
authors.initials: F
authors.lastname: Verzini
authors.forename: P
authors.initials: P
authors.lastname: De Rango
authors.forename: S
authors.initials: S
authors.lastname: Zannetti
authors.forename: A
authors.initials: A
authors.lastname: Bufalari
authors.forename: G
authors.initials: G
authors.lastname: Giordano