title: Monitoring perspiration from palms of hypohidrosis patients with a stopped-flow conductometric mini-system.
abstract: BACKGROUND
  Sensitive and real-time methods are required to characterize the symptoms and resolve the complicated pathology of hypohidrosis.
  
  
  METHODS
  We constructed a conductometric humidity sensor and a stopped-flow manifold with suitable dynamic range for monitoring impaired perspiration. The mini-sensor was coated with a water-absorbing polymer of poly-(2-acrylamido-2-methylpropane sulfonate).
  
  
  RESULTS
  Perspiration from palms of normal individuals and hypohidrosis patients were monitored and compared. Tangent slopes of the sensorograms were capable of discriminating hypohidrosis patients from normal individuals.
  
  
  CONCLUSIONS
  The conductometric min-sensor and the stopped-flow manifold were proven to be useful as a diagnostic tool for hypohidrosis.
authors.affiliation: Institute of Biomedical Engineering, National Cheng-kung University, Tainan, Taiwan, ROC.
authors.forename: Bin-Wha
authors.initials: BW
authors.lastname: Chang
authors.forename: Shoou-Jeng
authors.initials: SJ
authors.lastname: Yeh
authors.forename: Ping-Ping
authors.initials: PP
authors.lastname: Tsai
authors.forename: Hsien-Chang
authors.initials: HC
authors.lastname: Chang
mesh_terms: D004553:Electric Conductivity; D006225:Hand; D006801:Humans; D006813:Humidity; D007007:Hypohidrosis / Q000175:diagnosis*; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods; D011108:Polymers; D012680:Sensitivity and Specificity; D013451:Sulfonic Acids; D013542:Sweat / Q000378:metabolism*; D013997:Time Factors
chemical_list: D011108:Polymers; D013451:Sulfonic Acids; C077118:poly(2-acrylamido-2-methyl-1-propanesulfonic acid)