The androgen insensitive micropenis: long-term follow-up into adulthood.
OBJECTIVE
To assess the adult stretched penile length (SPL) and sexuality in patients with micropenis who exhibited an inadequate response to exogenous testosterone therapy and were raised as males.


METHODS
Patients with micropenis who had an equivocal response to exogenous testosterone therapy and were raised as males were evaluated at adulthood (>17 yr).


CONCLUSIONS
Twenty patients with micropenis, initial median SPL -3.3 SD below the mean (range -5.5 to -2.6) had a suboptimal response to initial testosterone therapy, median SPL post-treatment -2.7 SD (-3.3 to -2.2), and were raised as males. At adulthood, 90% (18/20) had a micropenis, median SPL -3.4 (-5.9 to -2.2). All have a male gender identity, five are undergoing psychiatric counseling (fear of sexual rejection--five patients, one of whom also has suicidal ideation). Eight have not pursued a sexual relationship; 12 are sexually active, one of whom is bisexual.
Husmann
D A
DA
Department of Urology, The Mayo Clinic, Rochester, MN 55905, USA. dhusmann@mayo.edu
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D005783:Gender Identity; D006801:Humans; D007006:Hypogonadism / Q000188:drug therapy / Q000523:psychology*; D007223:Infant; D008297:Male; D010413:Penis / Q000002:abnormalities* / Q000254:growth & development; D019529:Sexuality / Q000502:physiology / Q000523:psychology*; D013739:Testosterone / Q000627:therapeutic use*; D016896:Treatment Outcome
D013739:Testosterone