Lack of increased left main coronary artery dimensions in hypertensive patients with left ventricular hypertrophy and coronary artery disease. An intracoronary ultrasound study.
OBJECTIVE
Left main coronary artery dimensions were evaluated in patients with and without arterial hypertension, in the presence of coronary artery disease, and correlated to left ventricular mass.


RESULTS
Intracoronary ultrasound was performed in 25 patients (pts) with coronary artery disease and hypertension (+HTN) and in 25 pts with coronary artery disease only (-HTN). Maximal left main dimensions and left ventricular mass index (LVMI) were measured. +HTN pts had greater LVMI compared to -HTN, (+HTN = 183 +/- 17 g/m2 vs. -HTN = 82 +/- 22 g/m2, p < 0.0001), while maximal left main vessel area was similar (25.99 +/- 5.01 mm2 vs. 25.62 +/- 3.3 mm2, p = 0.8). No correlation was found between LVMI and left main vessel area in + HTN.


CONCLUSIONS
Pts with +HTN despite the increased LVMI do not manifest increased LM dimensions. This may affect mid-term clinical outcome.
Vavuranakis
Manolis
M
Hippokration Hospital, Department of Cardiology, University of Athens, Greece. mvav@otenet.gr
Rigopoulos
Agelos
A
Vaina
Sofia
S
Chrysohoou
Christina
C
Toutouzas
Konstantinos
K
Stamatopoulos
Ilias
I
Stefanadis
Christodoulos
C
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000368:Aged; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D001158:Arteries / Q000000981:diagnostic imaging* / Q000473:pathology*; D001794:Blood Pressure / Q000187:drug effects; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D003331:Coronary Vessels / Q000000981:diagnostic imaging* / Q000473:pathology*; D003971:Diastole / Q000187:drug effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D017379:Hypertrophy, Left Ventricular / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000627:therapeutic use; D015588:Observer Variation; D013223:Statistics as Topic; D013599:Systole / Q000187:drug effects; D016896:Treatment Outcome; D017539:Tunica Intima / Q000000981:diagnostic imaging / Q000473:pathology; D018084:Ultrasonography, Interventional; D014665:Vasodilator Agents / Q000627:therapeutic use
D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D002121:Calcium Channel Blockers; D014665:Vasodilator Agents; D005996:Nitroglycerin