title: Local recurrence following surgical treatment for carcinoma of the lower rectum.
abstract: BACKGROUND
  The present paper examines the local recurrence rate following surgical treatment for carcinoma of the lower rectum with principally blunt dissection directed at tumour-specific mesorectal excision (including total mesorectal excision when appropriate).
  
  
  METHODS
  During the period April 1987-December 1999, 123 consecutive resections for carcinoma of the middle and distal thirds of the rectum were performed. The patients had low anterior resection, ultra low anterior resection or abdomino-perineal resection. Ninety-six eligible patients underwent curative resection. The mean follow-up period was 66.8 months +/-44.3 (range 3-176 months). Data were available on all patients having been prospectively registered and retrospectively collated and computer coded.
  
  
  RESULTS
  The overall rate of local recurrence was 5.2% (four recurrences following ultra low anterior resection and one following abdomino-perineal resection. No local recurrence occurred after low anterior resections.). Local recurrences occurred between 16 and 52 months from the time of resection, and the cumulative risk of developing local recurrence at 5 years for all patients was 7.6%. The overall 5-year cancer specific survival of the 96 patients was 80.8%, and the overall probability of being disease free at 5 years, including both local and distal recurrence, was 71.8%.
  
  
  CONCLUSIONS
  The results of the present series confirm the safety of careful blunt techniques combined with sharp dissection for rectal mobilization along fascial planes resulting in extraction of an oncologic package with tumour-specific mesorectal excision (or total mesorectal excision when appropriate).
authors.affiliation: Cabrini Monash University Academic Surgical Department, Cabrini Hospital, Melbourne, Victoria, Australia. adrian.polglase@med.monash.edu.au
authors.forename: Adrian L
authors.initials: AL
authors.lastname: Polglase
authors.forename: Simon F
authors.initials: SF
authors.lastname: Grodski
authors.forename: Ann B
authors.initials: AB
authors.lastname: Tremayne
authors.forename: Justin B L
authors.initials: JB
authors.lastname: Chee
authors.forename: Prithi S
authors.initials: PS
authors.lastname: Bhathal
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D000368:Aged; D004210:Dissection / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008646:Mesocolon / Q000601:surgery; D009364:Neoplasm Recurrence, Local; D012004:Rectal Neoplasms / Q000601:surgery*; D016896:Treatment Outcome