title: Ability of troponin T to predict angiographic coronary artery disease in patients with chronic kidney disease.
abstract: Association between angiographic coronary artery disease and cardiac troponin T levels has been observed in patients with normal kidney function; however, this association remains unsettled in patients with chronic kidney disease (CKD) or end-stage renal disease (ESRD). Over a 12-month period we retrospectively reviewed coronary angiograms (CAs) performed in 194 hospitalized patients with presumed acute myocardial injury. About 50% of the ESRD and 30% of the CKD patients had normal CAs. Troponin T levels significantly correlated with CAs in patients with normal kidney function (r = 0.4, p = 0.005) but not in ESRD and CKD patients (r = 0.2, p = NS, respectively).
authors.affiliation: Department of Medicine, Morehouse School of Medicine, Grady Memorial Hospital, 720 West View Drive SW, Atlanta, GA 30310, USA. obialoc@msm.edu
authors.forename: Chamberlain I
authors.initials: CI
authors.lastname: Obialo
authors.forename: Shalini
authors.initials: S
authors.lastname: Sharda
authors.forename: Smriti
authors.initials: S
authors.lastname: Goyal
authors.forename: Elizabeth O
authors.initials: EO
authors.lastname: Ofili
authors.forename: Adefisayo
authors.initials: A
authors.lastname: Oduwole
authors.forename: Nancy
authors.initials: N
authors.lastname: Gray
mesh_terms: D017023:Coronary Angiography; D003327:Coronary Disease / Q000097:blood* / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D020107:Troponin T / Q000097:blood*
chemical_list: D020107:Troponin T