title: [Our experience with the sentinel lymph node detection].
abstract: BACKGROUND
  Axillary lymph node staging is the most powerful predictor of survival in breast cancer women. Sentinel lymph node biopsy (SLNB) is more accurate method in evaluation of axillary lymph node staging than complete axillary lymph node dissection (CALND) because of more precious histological and imunohistochemical assessment of the first draining lymph nodes. Furthermore, SLNB eliminates complications resulting from CALND.
  
  
  METHODS
  SLNB is either performed using blue dye technique or using of combination of blue dye and radioguided technique. We prefer two days protocol in application of Tc 99 radiocolloid. There were used both techniques for detection sentinel lymph nodes and results were compared.
  
  
  RESULTS
  There were performed 21 SLNBs using blue dye technique, Group A, and 20 SLNBs using combination of blue dye and radioguided technique, Group B, from October 2001 to November 2003. Sentinel lymph nodes were not detected in Group A in two cases, false negativity occurred two times in this group. Sentinel lymph nodes were detected in all cases in Group B and there was no false negativity present in this group.
  
  
  CONCLUSIONS
  Combination of blue dye and radioguided technique is more precious in detection of sentinel lymph node than blue dye technique itself. Two days protocol of application of Tc 99 radiocolloid enables performing this method even in hospitals, where the Department of Nuclear Medicine is not available.
authors.affiliation: Chirurgická klinika nemocnice Pardubice.
authors.forename: V
authors.initials: V
authors.lastname: Cervinka
authors.forename: K
authors.initials: K
authors.lastname: St'astný
authors.forename: K
authors.initials: K
authors.lastname: Havlícek
authors.forename: I
authors.initials: I
authors.lastname: Vyhnánková
authors.forename: J
authors.initials: J
authors.lastname: Vanásek
authors.forename: E
authors.initials: E
authors.lastname: Pavlíková
authors.forename: P
authors.initials: P
authors.lastname: Rothröckel
authors.forename: M
authors.initials: M
authors.lastname: Hácová
authors.forename: L
authors.initials: L
authors.lastname: Nechvátal
mesh_terms: D000328:Adult; D000368:Aged; D001365:Axilla; D001943:Breast Neoplasms / Q000473:pathology*; D004396:Coloring Agents; D005260:Female; D006801:Humans; D008751:Methylene Blue; D008875:Middle Aged; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*; D013667:Technetium
chemical_list: D004396:Coloring Agents; D013667:Technetium; D008751:Methylene Blue
vernacular_title: Nase zkusenosti s detekcí sentinelové uzliny.