One-pot homolytic aromatic substitutions/HWE olefinations under microwave conditions for the formation of a small oxindole library.
[reaction: see text] An efficient one-pot sequence comprising a homolytic aromatic substitution followed by an ionic Horner-Wadsworth-Emmons olefination for the preparation of a small library of alpha,beta-unsaturated oxindoles is presented. Microwave-induced heating is used to conduct these reactions. The homolytic aromatic substitution is mediated by the persistent radical effect.
Teichert
Antje
A
Fachbereich Chemie, Philipps-Universität Marburg, 35032 Marburg, Germany.
Jantos
Katja
K
Harms
Klaus
K
Studer
Armido
A