Analytical correlation between plasma N-terminal pro-brain natriuretic peptide and brain natriuretic peptide in patients presenting with dyspnea.
OBJECTIVE
We examined the analytical correlation N-terminal pro-brain natriuretic peptide (NT-proBNP) and brain natriuretic peptide (BNP).


METHODS
Electrochemiluminescence and fluorescence immunoassays were used to measure NT-proBNP and BNP levels, respectively.


RESULTS
The analytical correlation was satisfactory using the equation: NT-proBNP = 8.56 x BNP + 91.7 and a correlation r = 0.85. The correlation was not influenced by age, gender and BMI of patients.


CONCLUSIONS
We conclude that NT-proBNP correlates with BNP.
Alibay
Yasmin
Y
Laboratoire de Biochimie-Génétique Moléculaire, Hôpital Ambroise Paré, 92104 Boulogne Billancourt Cedex, France.
Beauchet
Alain
A
El Mahmoud
Rami
R
Brun-Ney
Dominique
D
Alexandre
Jeanne-Armelle
JA
Benoit
Marie-Odile
MO
Dubourg
Olivier
O
Aegerter
Philippe
P
Boileau
Catherine
C
Jondeau
Guillaume
G
Puy
Hervé
H
D000368:Aged; D000369:Aged, 80 and over; D004417:Dyspnea / Q000097:blood / Q000175:diagnosis*; D004563:Electrochemistry; D005260:Female; D005453:Fluorescence; D006801:Humans; D007118:Immunoassay; D008163:Luminescent Measurements; D008297:Male; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D009419:Nerve Tissue Proteins / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood*; D011379:Prognosis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D009419:Nerve Tissue Proteins; D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain