title: [Global respiratory failure as the presentation form of hypothyroidism. Report of one case].
abstract: We report a 36 years male, admitted to the hospital for progressive respiratory failure. Chest X ray and CT scan were normal. On admission, a severe bradycardia and slow intellectual activity were noted. Serum thyroid function tests showed a TSH over 150 microU/ml and T3 of 75 ng/ml. Thyroid substitution therapy was associated with a progressive improvement of respiratory function. Diaphragmatic dysfunction, central hypoventilation, airway obstruction, sleep apnea and pleural effusion have been previously reported in patients with hypothyroidism. Therefore, we recommend to measure TSH in patients with unexplained respiratory failure.
authors.affiliation: Departamento de Endocrinología, Servicio de Medicina del Hospital Dr. Gustavo Fricke de Viña del Mar. chavez.novik@entelchile.net
authors.forename: Victoria
authors.initials: V
authors.lastname: Novik
authors.forename: M Eugenia
authors.initials: ME
authors.lastname: Pérez
authors.forename: Gabriel
authors.initials: G
authors.lastname: Anwandter
mesh_terms: D000328:Adult; D006801:Humans; D007037:Hypothyroidism / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D012131:Respiratory Insufficiency / Q000188:drug therapy / Q000209:etiology*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000627:therapeutic use
chemical_list: D013972:Thyrotropin; D013974:Thyroxine
vernacular_title: Insuficiencia respiratoria global como forma de presentación de un hipotiroidismo. Comunicación de un caso.