title: SSFP-based MR thermometry.
abstract: Of the various techniques employed to quantify temperature changes by MR, proton resonance frequency (PRF) shift-based phase-difference imaging (PDI) is the most accurate and widely used. However, PDI is associated with various artifacts. Motivated by these limitations, we developed a new method to monitor temperature changes by MRI using the balanced steady-state free precession (balanced-SSFP) pulse sequence. Magnitude images obtained with the SSFP pulse sequence were used to find the PRF shift, which is proportional to temperature change. Spatiotemporal temperature maps were successfully reconstructed with this technique in gel phantom experiments and a rabbit model. The results show that the balanced-SSFP-based method is a promising new technique for monitoring temperature.
authors.affiliation: Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205, USA.
authors.forename: Vaishali
authors.initials: V
authors.lastname: Paliwal
authors.forename: AbdEl-Monem
authors.initials: AM
authors.lastname: El-Sharkawy
authors.forename: Xiangying
authors.initials: X
authors.lastname: Du
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Yang
authors.forename: Ergin
authors.initials: E
authors.lastname: Atalar
mesh_terms: D000818:Animals; D005782:Gels; D006358:Hot Temperature; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019047:Phantoms, Imaging; D011817:Rabbits; D013817:Thermography
chemical_list: D005782:Gels