Oral pemphigus vulgaris: a case report and literature update.
BACKGROUND
Pemphigus vulgaris is a rare cause of oral mucosal ulceration.


METHODS
A 47-year-old Chinese man presented with a 3-month history of oral ulceration. There were no lesions on the skin or other mucosal sites. Histology and immunostaining were consistent with pemphigus vulgaris.


METHODS
Systemic and topical corticosteroids were instituted, together with topical antifungals. Conventional periodontal therapy was carried out to improve gingival/oral health.


RESULTS
Control of oral ulceration was achieved with re-establishment of normal oral function. No other sites to date have been involved.


CONCLUSIONS
Chronic oral ulceration can be the sole manifestation of pemphigus vulgaris, at least initially. Early recognition of this lesion may prevent delayed diagnosis and inappropriate treatment of a potentially chronic dermatological condition.
Robinson
N A
NA
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, National University Hospital, Singapore.
Yeo
J F
JF
Lee
Y S
YS
Aw
D C
DC
D000935:Antifungal Agents / Q000008:administration & dosage; D002927:Cimetidine / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000188:drug therapy / Q000473:pathology*; D010392:Pemphigus / Q000188:drug therapy / Q000473:pathology*; D011239:Prednisolone / Q000008:administration & dosage
D000935:Antifungal Agents; D002927:Cimetidine; D011239:Prednisolone