Complete assignment of 1H and 13C NMR data for three aryltetralin lignan lactones.
We describe the complete 1H and 13C NMR analysis of three aryltetralin lignan lactones (polygamain, morelensin and 4,5-dimethoxymorelensin) using modern NMR techniques such as COSY, HMQC, HMBC, 2D-J-resolved and NOE experiments. The relative stereochemistry of these compounds, which is very important with regard to their biological activity, was completely determined.
da Silva
Rosangela
R
Departamento de Análises Clínicas, Toxicológicas e Bromatológicas da Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Avenida do Café, s/n, 14040-903 Ribeirão Preto, SP, Brazil. rosilva@usp.br
Heleno
Vladimir Constantino Gomes
VC
de Albuquerque
Sérgio
S
Bastos
Jairo Kenupp
JK
Andrade e Silva
Márcio Luis
ML
Donate
Paulo Marcos
PM
da Silva
Gil Valdo José
GV
D001572:Benzofurans / Q000138:chemical synthesis / Q000737:chemistry*; D001681:Biological Assay; D002247:Carbon Isotopes; D004149:Dioxoles / Q000138:chemical synthesis / Q000737:chemistry*; D006859:Hydrogen; D007783:Lactones / Q000138:chemical synthesis / Q000737:chemistry*; D017705:Lignans / Q000138:chemical synthesis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
C499778:4,5-dimethoxymorelensin; D001572:Benzofurans; D002247:Carbon Isotopes; D004149:Dioxoles; D007783:Lactones; D017705:Lignans; C499777:morelensin; C499776:polygamain; D006859:Hydrogen