title: [Analysis of tablets containing the antihistamine loratadine: a contribution to the identification of impurities].
abstract: Thin-layer chromatography on silica gel (Merck) was employed to examine potential impurities present in loratadine-containing tablets. A method usable for testing of impurities was elaborated, which suitably supplements the determination of loratadine content using the spectrophotometric method in the UV region. The method was validated for selected pharmaceuticals.
authors.affiliation: Státny ústav pre kontrolu lieciv, Bratislava.
authors.forename: N
authors.initials: N
authors.lastname: Issa
authors.forename: M
authors.initials: M
authors.lastname: Mlynárová
mesh_terms: D002855:Chromatography, Thin Layer; D004340:Drug Contamination; D039563:Histamine H1 Antagonists, Non-Sedating / Q000032:analysis*; D017336:Loratadine / Q000032:analysis*; D013607:Tablets / Q000737:chemistry*
chemical_list: D039563:Histamine H1 Antagonists, Non-Sedating; D013607:Tablets; D017336:Loratadine
vernacular_title: Analýza tabliet s obsahom loratadínu (antihistaminikum) príspevok k identifikácii necistôt.