title: Predicting allogeneic blood transfusion use in total joint arthroplasty.
abstract: Total joint arthroplasty (TJA) patients often receive allogeneic blood transfusion. In this study we sought to create and validate a clinical prediction rule for transfusion in TJA using data that are easily available when scheduling the procedure. Logistic regression modeling was applied to retrospective data from all TJA procedures performed in Edmonton, Alberta in 2000 (n = 1875). The area under the receiver operating curve for the resulting model in the training and validation data sets was 0.80 and 0.76 respectively. By assigning a simple score based on six independent predictors (age, gender, weight, hemoglobin, ASA operative risk classification and whether revision surgery was planned), it was possible to classify a given subject's risk of receiving allogeneic transfusion. We conclude that accurate prediction of transfusion risk in TJA is possible using a rule based on simple preoperative clinical and laboratory data. Such prediction could allow transfusion prevention strategies to be applied selectively to those at greatest risk.
authors.affiliation: Department of Anesthesiology and Pain Medicine, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Saifudin
authors.initials: S
authors.lastname: Rashiq
authors.forename: Meera
authors.initials: M
authors.lastname: Shah
authors.forename: Ava K
authors.initials: AK
authors.lastname: Chow
authors.forename: Paul J
authors.initials: PJ
authors.lastname: O'Connor
authors.forename: Barry A
authors.initials: BA
authors.lastname: Finegan
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000758:Anesthesia; D019643:Arthroplasty, Replacement; D001185:Artificial Intelligence; D001803:Blood Transfusion / Q000706:statistics & numerical data*; D001827:Body Height; D001835:Body Weight; D016208:Databases, Factual; D017707:Erythrocyte Transfusion; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D018570:Risk Assessment; D012737:Sex Factors