title: Computational analysis of an axial flow pediatric ventricular assist device.
abstract: Longer-term (>2 weeks) mechanical circulatory support will provide an improved quality of life for thousands of pediatric cardiac failure patients per year in the United States. These pediatric patients suffer from severe congenital or acquired heart disease complicated by congestive heart failure. There are currently very few mechanical circulatory support systems available in the United States as viable options for this population. For that reason, we have designed an axial flow pediatric ventricular assist device (PVAD) with an impeller that is fully suspended by magnetic bearings. As a geometrically similar, smaller scaled version of our axial flow pump for the adult population, the PVAD has a design point of 1.5 L/min at 65 mm Hg to meet the full physiologic needs of pediatric patients. Conventional axial pump design equations and a nondimensional scaling technique were used to estimate the PVAD's initial dimensions, which allowed for the creation of computational models for performance analysis. A computational fluid dynamic analysis of the axial flow PVAD, which measures approximately 65 mm in length by 35 mm in diameter, shows that the pump will produce 1.5 L/min at 65 mm Hg for 8000 rpm. Fluid forces (approximately 1 N) were also determined for the suspension and motor design, and scalar stress values remained below 350 Pa with maximum particle residence times of approximately 0.08 milliseconds in the pump. This initial design demonstrated acceptable performance, thereby encouraging prototype manufacturing for experimental validation.
authors.affiliation: Biomedical Engineering Department, Virginia Artificial Heart Institute, University of Virgina, Charlottesville, VA 22908, USA. alt2c@virginia.edu
authors.forename: Amy L
authors.initials: AL
authors.lastname: Throckmorton
authors.forename: Alexandrina
authors.initials: A
authors.lastname: Untaroiu
authors.forename: Paul E
authors.initials: PE
authors.lastname: Allaire
authors.forename: Houston G
authors.initials: HG
authors.lastname: Wood
authors.forename: Gaynell Paul
authors.initials: GP
authors.lastname: Matherne
authors.forename: David Scott
authors.initials: DS
authors.lastname: Lim
authors.forename: Ben B
authors.initials: BB
authors.lastname: Peeler
authors.forename: Don B
authors.initials: DB
authors.lastname: Olsen
mesh_terms: D000465:Algorithms; D001243:Assisted Circulation / Q000295:instrumentation*; D001698:Biomedical Engineering; D001775:Blood Circulation; D001783:Blood Flow Velocity; D002648:Child; D003198:Computer Simulation; D006354:Heart, Artificial; D006353:Heart-Assist Devices; D006801:Humans