title: Expression of cell cycle-dependent genes and proliferative state of lymphocytes in aging.
abstract: The authors analyzed the expression of some genes involved in the control of T lymphocyte proliferation in a group of healthy elderly subjects. They focused their attention on genes involved in the G(0)/G(1) transition (TK, PCNA, H3, IL2-R) and showed decreased expression in the TK, H3 and IL2-R genes. Using flow cytofluorimetry, delayed transition from the G(0)/G(1) to the S stage was observed.
authors.affiliation: Istituto di Patologia Generale, Università di Catania, Catania, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Travali
authors.forename: G
authors.initials: G
authors.lastname: Carnazzo
authors.forename: A M
authors.initials: AM
authors.lastname: Distefano
authors.forename: P
authors.initials: P
authors.lastname: Manciagli
authors.forename: C
authors.initials: C
authors.lastname: Cosenza
authors.forename: E
authors.initials: E
authors.lastname: Fidone
authors.forename: S
authors.initials: S
authors.lastname: Petralia
authors.forename: A
authors.initials: A
authors.lastname: Bernardini
authors.forename: L
authors.initials: L
authors.lastname: Motta
authors.forename: F
authors.initials: F
authors.lastname: Stivala