[Medical treatment of hypertension--what treatment for what patients?].
The antihypertensive agents of first choice include ACE-inhibitors, angiotensin receptor blockers, beta blockers, calcium antagonists and diuretic agents. For the selection of medicaments, the individual patient risk profile of decisive importance. In particular a metabolic syndrome, diabetes mellitus, disturbed renal function and/or a disturbed electrolyte household must be considered. For initial treatment monotherapy or a low-dose combination regime is suggested. If the response is inadequate, possible options include increasing the dose, changing the medicament, (sequential monotherapy) or, in the sense of stepped treatment, introduction of further combination drugs. Resistance to therapy should prompt consideration of a number of causes, in particular noncompliance on the part of the patient.
Zidek
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Medizinischen Klinik IV Charité, Universitätsmedizin Berlin. Walter.Zidek@charite.de
Tepel
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van der Giet
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D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D047228:Angiotensin II Type 1 Receptor Blockers; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000627:therapeutic use; D048909:Diabetes Complications; D004232:Diuretics / Q000008:administration & dosage / Q000627:therapeutic use; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D006333:Heart Failure / Q000150:complications; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy*; D010349:Patient Compliance; D051437:Renal Insufficiency / Q000150:complications; D012307:Risk Factors
D000319:Adrenergic beta-Antagonists; D047228:Angiotensin II Type 1 Receptor Blockers; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D004232:Diuretics
Medikamentöse Hochdrucktherapie: Welche Strategie für welchen Patienten? 08/15 gibt es nicht!