Disulfiram-induced fulminant hepatic failure in an active duty soldier.
Fulminant hepatic failure is a rare complication of disulfiram treatment for alcoholism. In the instances that it does occur, previous liver disease or failure to be abstinent from alcohol are thought to be causative. This case describes fulminant hepatic failure in a patient taking disulfiram with no previous liver disease and report of being compliant with alcohol abstinence. Careful pretreatment screening and rigorous monitoring patients are recommended to help prevent this life-threatening event.
Mendenhall
Marshall
M
Department of Family Practice, Madigan Army Medical Center, Fort Lewis, WA 98431, USA.
D000328:Adult; D000427:Alcohol Deterrents / Q000009:adverse effects*; D000437:Alcoholism / Q000188:drug therapy*; D004221:Disulfiram / Q000009:adverse effects*; D006801:Humans; D017093:Liver Failure / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male; D008889:Military Personnel
D000427:Alcohol Deterrents; D004221:Disulfiram