title: Reactive arthritis. Immune-mediated synovitis or joint infection.
abstract: Reactive arthritis is one form of the seronegative Spondyloarthropathies. Susceptibility to reactive arthritis is closely linked to individuals who have the genetic predisposition to the HLA-B27 allele (gene form). Although there is a reactive-inflammatory joint reaction present, the synovium is not damaged by infectious agents (bacteria, fungi, or virus). This article discusses the pathogenesis of reactive arthritis.
authors.forename: Sharon G
authors.initials: SG
authors.lastname: Childs
mesh_terms: D016918:Arthritis, Reactive / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D001172:Arthritis, Rheumatoid / Q000276:immunology / Q000503:physiopathology; D016207:Cytokines / Q000378:metabolism; D003937:Diagnosis, Differential; D006801:Humans; D017746:Joint Capsule / Q000276:immunology / Q000378:metabolism / Q000503:physiopathology; D013585:Synovitis / Q000276:immunology / Q000503:physiopathology
chemical_list: D016207:Cytokines