title: Critical stenosis of aortic and mitral valves after mediastinal irradiation.
abstract: Radiotherapy is used widely in cancer treatment. Mediastinal irradiation is associated with valvular regurgitation; however, stenosis is rare. We present a patient with critical aortic and mitral valve stenosis after mediastinal irradiation and discuss the natural history, treatment, and prognosis of radiation-associated valvular heart disease.
authors.affiliation: Divisions of Cardiology, Cardiovascular Surgery and Pathology Veterans Affairs Medical Center, Minneapolis, Minnesota 55405, USA. adaba001@umn.edu
authors.forename: A Selcuk
authors.initials: AS
authors.lastname: Adabag
authors.forename: Richard
authors.initials: R
authors.lastname: Dykoski
authors.forename: Herbert
authors.initials: H
authors.lastname: Ward
authors.forename: Inder S
authors.initials: IS
authors.lastname: Anand
mesh_terms: D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging / Q000209:etiology*; D017548:Echocardiography, Transesophageal; D006689:Hodgkin Disease / Q000188:drug therapy / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000000981:diagnostic imaging / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*