title: Mechanisms of cardiovascular protection by resveratrol.
abstract: The phytoantitoxin resveratrol is a plant-derived polyphenol with phytoestrogenic properties. Resveratrol protects the cardiovascular system by mechanisms that include defense against ischemic-reperfusion injury, promotion of vasorelaxation, protection and maintenance of intact endothelium, anti-atherosclerotic properties, inhibition of low-density lipoprotein oxidation, suppression of platelet aggregation, and estrogen-like actions. The purpose of this article is to review the mechanisms of these effects.
authors.affiliation: Postgraduate School, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
authors.forename: Han Dong
authors.initials: HD
authors.lastname: Hao
authors.forename: Li Ren
authors.initials: LR
authors.lastname: He
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D000975:Antioxidants / Q000627:therapeutic use*; D002317:Cardiovascular Agents / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000188:drug therapy / Q000517:prevention & control*; D002455:Cell Division / Q000187:drug effects; D006801:Humans; D048789:Phytoestrogens / Q000627:therapeutic use; D000077185:Resveratrol; D015398:Signal Transduction / Q000187:drug effects; D013267:Stilbenes / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000972:Antineoplastic Agents, Phytogenic; D000975:Antioxidants; D002317:Cardiovascular Agents; D048789:Phytoestrogens; D013267:Stilbenes; D000077185:Resveratrol