title: Diffusion MR findings in cyclosporin-A induced encephalopathy.
abstract: Cyclosporin encephalopathy is a well-known entity, which is clinically characterized by altered mental status, vision problems, focal neurological deficits and seizures. The exact pathophysiology of the cyclosporin encephalopathy has not yet been defined. We report the diffusion-weighted MR imaging and proton MR spectroscopy findings in a case of cyclosporin encephalopathy. The white-matter lesions with reversible restricted diffusion supported the hypothesis of reversible vasospasm induced by the cyclosporin.
authors.affiliation: Neuroradiology Division, Department of Radiology, Istanbul Medical School, Istanbul University, Istanbul, Turkey.
authors.forename: Kubilay
authors.initials: K
authors.lastname: Aydin
authors.forename: Fuldem
authors.initials: F
authors.lastname: Donmez
authors.forename: Umit
authors.initials: U
authors.lastname: Tuzun
authors.forename: Ozenc
authors.initials: O
authors.lastname: Minareci
authors.forename: Tanju
authors.initials: T
authors.lastname: Atamer
mesh_terms: D000328:Adult; D001921:Brain / Q000378:metabolism / Q000473:pathology; D001927:Brain Diseases / Q000139:chemically induced* / Q000175:diagnosis*; D016572:Cyclosporine / Q000037:antagonists & inhibitors*; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D007166:Immunosuppressive Agents / Q000037:antagonists & inhibitors*; D009682:Magnetic Resonance Spectroscopy; D008297:Male
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine