A short diastereoselective synthesis of orthogonally protected diaminosuccinic acid derivatives.
Homogeneous, Rh-catalyzed hydrogenation of heteromeric olefinic glycine dimers presents an efficient route to diastereomerically pure, orthogonally protected diaminosuccinic acid derivatives depending on the double bond geometry of the starting material. The products were obtained as racemates.
Zeitler
Kirsten
K
Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13 (Haus F), D-81377 München, Germany.
Steglich
Wolfgang
W
D000599:Amino Acids, Diamino / Q000138:chemical synthesis*; D002384:Catalysis; D005998:Glycine / Q000737:chemistry*; D006865:Hydrogenation; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
D000599:Amino Acids, Diamino; C031934:diaminosuccinic acid; D012238:Rhodium; D005998:Glycine