Long polar fimbriae contribute to colonization by Escherichia coli O157:H7 in vivo.
The contribution of long polar fimbriae to intestinal colonization by Escherichia coli O157:H7 was evaluated in sheep, conventional pigs, and gnotobiotic piglets. E. coli O157:H7 strains with lpfA1 and lpfA2 mutated were recovered in significantly lower numbers and caused fewer attachment and effacement lesions than the parent strain.
Jordan
Dianna M
DM
Department of Veterinary Pathology, Iowa State University, Ames, Iowa 50011, USA. dmjordan@iastate.edu
Cornick
Nancy
N
Torres
Alfredo G
AG
Dean-Nystrom
Evelyn A
EA
Kaper
James B
JB
Moon
Harley W
HW
D000818:Animals; D004927:Escherichia coli Infections / Q000382:microbiology / Q000473:pathology; D019453:Escherichia coli O157 / Q000145:classification* / Q000235:genetics / Q000472:pathogenicity* / Q000502:physiology; D029968:Escherichia coli Proteins / Q000235:genetics / Q000378:metabolism; D005243:Feces / Q000382:microbiology; D010861:Fimbriae, Bacterial / Q000737:chemistry* / Q000235:genetics / Q000502:physiology*; D005516:Food Microbiology; D007422:Intestines / Q000382:microbiology* / Q000473:pathology; D009154:Mutation / Q000235:genetics; D012756:Sheep / Q000382:microbiology*; D013552:Swine / Q000382:microbiology*
D029968:Escherichia coli Proteins