Structure determination of ramosine, a guaianolide, by NMR spectroscopy.
Ramosine, a new sesquiterpene lactone, was isolated from the chloroform fraction of Amberboa ramosa and the structure was assigned as 4beta-(hydroxymethyl)-3beta,4alpha-dihydroxy-8alpha-[(S)-3-hydroxy-2-ethylenepropionyloxy]-1alphaH, 5alphaH,6betaH,7alphaH,11betaH,11alpha-methylguaia-10(14)-en-6, 12-olide by extensive NMR studies.
Khan
Sher Bahadar
SB
International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.
Afza
Nighat
N
Malik
Abdul
A
ul Haq
Azhar
A
Ahmed
Zaheer
Z
D002725:Chloroform / Q000737:chemistry; D007783:Lactones / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008968:Molecular Conformation; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry*
D007783:Lactones; D012717:Sesquiterpenes; C499646:ramosine; D002725:Chloroform