Upper limb abnormalities in mosaic trisomy 8 syndrome.
BACKGROUND
Skeletal abnormalities are known to be a characteristic feature of the trisomy 8 syndrome, and radiological malformations are often more characteristic than the clinical features.


METHODS
We report a mentally retarded male known to have mosaic trisomy 8 syndrome who presented with radial deviation of his right wrist. Radiographs showed an open ulna epiphysis with a closed radial epiphysis. Surgery was postponed until an older age as his ulna epiphysis had not yet closed, but clinical correction was achieved with a wrist brace.


CONCLUSIONS
This is the first report of radial deviation of the wrist in a patient with mosaic trisomy 8.
Alvi
F
F
alvi@btinternet.com
Alonso
A
A
Brewood
A F M
AF
D000293:Adolescent; D001133:Bones of Upper Extremity / Q000002:abnormalities*; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D008607:Intellectual Disability; D008297:Male; D009030:Mosaicism; D013577:Syndrome; D014314:Trisomy; D014955:Wrist Joint / Q000002:abnormalities*