A case of listerial meningitis treated with a regimen containing panipenem-betamipron.
Although panipenem-betamipron, which is commercially available only in Japan, is recommended for treatment of pediatric bacterial meningitis by some experts, only a limited number of clinical studies have been reported. In the present report, we describe a 2-year-old boy with meningitis caused by Listeria monocytogenes who was treated with a regimen containing panipenem-betamipron and recovered without any apparent neurological sequelae. On the basis of our experience and previous reports, panipenem-betamipron appears to be effective for the treatment of listerial meningitis.
Hitomi
Shigemi
S
Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan. shitomi@md.tsukuba.ac.jp
Ohto
Tatsuyuki
T
Okamoto
Miho
M
Nishimura
Yoko
Y
Iwasaki
Nobuyuki
N
Matsui
Akira
A
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D006801:Humans; D008089:Listeria monocytogenes / Q000187:drug effects*; D008297:Male; D008584:Meningitis, Listeria / Q000188:drug therapy* / Q000382:microbiology; D013845:Thienamycins / Q000627:therapeutic use*; D016896:Treatment Outcome; D015091:beta-Alanine / Q000031:analogs & derivatives / Q000627:therapeutic use*
D000900:Anti-Bacterial Agents; D013845:Thienamycins; D015091:beta-Alanine; C075316:panipenem-betamipron