title: Structural characterization and quantitation of compound loading of disubstituted benzoates bound to Wang resin through high-resolution magic angle spinning NMR spectroscopy.
abstract: The combination of 1D and 2D high-resolution magic angle spinning NMR experiments led to the assignment of the proton and carbon resonances for several disubstituted benzoates bound to a polystyrene resin through a Wang linker. It is shown that the signal corresponding to the methylene protons of the linker can be utilized to monitor the solid-phase reactions and determine the loading of the compounds on the resin.
authors.affiliation: Centro de Investigación Lilly, Avenida de la Industria 30, 28108 Alcobendas, Madrid, Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Blas
authors.forename: Alfonso
authors.initials: A
authors.lastname: Rivera-Sagredo
authors.forename: Rafael
authors.initials: R
authors.lastname: Ferritto
authors.forename: Juan Felix
authors.initials: JF
authors.lastname: Espinosa