title: Organic nanoparticles whose size and rigidity are finely tuned by cross-linking the end groups of dendrimers.
abstract: Dendrimers with molecular weights ranging from ca. 2700 to 11 000 and from 16 to 64 homoallyl ether end groups were cross-linked using the Grubbs ring-closing metathesis reaction. A combination of SEC, MALDI-TOF-MS, and AFM were used to characterize the cross-linked nanoparticles. The data suggest a significant decrease in volume with cross-linking and a concomitant increase in rigidity, both of which can be controlled independently with a fair degree of precision.
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign, 600 S. Matthews Avenue, Urbana, IL 61801, USA.
authors.forename: N Gabriel
authors.initials: NG
authors.lastname: Lemcoff
authors.forename: Tighe A
authors.initials: TA
authors.lastname: Spurlin
authors.forename: Andrew A
authors.initials: AA
authors.lastname: Gewirth
authors.forename: Steven C
authors.initials: SC
authors.lastname: Zimmerman
authors.forename: James B
authors.initials: JB
authors.lastname: Beil
authors.forename: Stephanie L
authors.initials: SL
authors.lastname: Elmer
authors.forename: H George
authors.initials: HG
authors.lastname: Vandeveer
mesh_terms: D003432:Cross-Linking Reagents / Q000737:chemistry; D004987:Ethers / Q000138:chemical synthesis / Q000737:chemistry*; D008970:Molecular Weight; D036103:Nanotechnology; D010316:Particle Size; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D003432:Cross-Linking Reagents; D004987:Ethers; D011108:Polymers