POEMS syndrome.
A middle-aged man presented with progressive dyspnea and a pleural effusion. He had slowly progressive bilateral symmetric extremity weakness, mediastinal lymphadenopathy, and splenomegaly. The diagnosis of POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, M-Protein and Skin changes was suspected clinically and confirmed with a bone marrow biopsy. He responded symptomatically to corticosteroids and is awaiting a stem cell transplant.
Goldstein
Mark
M
University of Connecticut School of Medicine, USA.
Bandyopadhyay
Tapas
T
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001856:Bone Marrow Examination; D003520:Cyclophosphamide / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D016878:POEMS Syndrome / Q000175:diagnosis* / Q000628:therapy*; D033581:Stem Cell Transplantation; D014057:Tomography, X-Ray Computed
D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide