[Food safety in the future: genes, molecular mechanisms and test systems].
The idenfication of the human genome makes it possible to investigate complex biological issues with new molecular techniques. Platformtechnologies such as DNA-Arrays or 2-D gelelectrophoresis combined with mass spectrometry will make it possible to have a faster look from gene to the protein and to find new target genes of compounds as well as new molecular mechanisms involved. The knowledge about complex molecular signalling pathways will give a real impact to new diagnostics in food analytics. As an example reporter gene assays as screening methods in the diagnostic of food contaminants will be discussed. Additionally, another example, the Novel Food will be discussed because the molecular techniques will improve diagnostics and the risk assessment of novel foods.
Lampen
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Lebensmitteltoxikologie, Institut für Lebensmitteltoxikologie und Chemische Analytik, Zentrum für Lebensmittelwissenschaften, Tierärztliche Hochschule Hannover. Alfonso.Lampen@tiho-hannover.de
D000818:Animals; D003257:Consumer Product Safety; D005506:Food Contamination / Q000032:analysis*; D016678:Genome; D006801:Humans; D008403:Mass Screening; D025202:Molecular Diagnostic Techniques; D020411:Oligonucleotide Array Sequence Analysis
Lebensmittelsicherheit in der Zukunft: Gene, molekulare Mechanismen und Testsysteme.