title: Development of maternal antibodies after oral vaccination of young female wild boar against classical swine fever.
abstract: An experimental study was performed to investigate the development of maternal antibodies after oral immunisation of young female wild boar against classical swine fever (CSF) using C-strain vaccine. Our results demonstrated that maternal antibodies do not persist in the offspring for more than 3 months. Based on the neutralising serum antibody titres, we assume that piglets of wild sows vaccinated orally twice or immunised once a long time before conception have protective antibodies for approximately 2 months. Furthermore, it seems that the level and the duration of maternal antibodies in the offspring are depend on the age of the female animals at the moment of vaccination as demonstrated in our experiment. The recent vaccination procedure consists of three double vaccinations in spring, summer and autumn. Especially vaccinations in summer and autumn could be crucial for transfer of high maternal antibody titres to the offspring.
authors.affiliation: Federal Research Centre for Virus Diseases of Animals, Friedrich-Loeffler-Institutes, Institute of Infectology, Boddenblick 5a, D-17493 Greifswald--Insel Riems, Germany. volder.kaden@rie.bfav.de
authors.forename: Volker
authors.initials: V
authors.lastname: Kaden
authors.forename: Elke
authors.initials: E
authors.lastname: Lange
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D000914:Antibodies, Viral / Q000096:biosynthesis* / Q000097:blood; D006691:Classical Swine Fever / Q000276:immunology* / Q000517:prevention & control; D006692:Classical Swine Fever Virus / Q000276:immunology*; D005260:Female; D007112:Immunity, Maternally-Acquired / Q000276:immunology*; D009500:Neutralization Tests / Q000662:veterinary; D011247:Pregnancy; D013552:Swine; D014611:Vaccination / Q000662:veterinary*; D014765:Viral Vaccines / Q000008:administration & dosage / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines