title: Usefulness of the calculated apparent diffusion coefficient value in the differential diagnosis of retroperitoneal masses.
abstract: OBJECTIVE
  To elucidate whether or not the apparent diffusion coefficient (ADC) values calculated from echo-planar diffusion-weighted (EPDW) MR images are useful in the differential diagnosis of retroperitoneal masses.
  
  
  METHODS
  In 50 patients with known retroperitoneal masses, EPDW images were performed with b-factors of 0-1100 seconds/mm2. The final histologic diagnoses of these lesions were as follows: 12 malignant lymphomas, four other malignant mesenchymal neoplasms, 25 malignant epithelial neoplasms, seven benign mesenchymal neoplasms, and two nonneoplastic lesions. The ADC values obtained for the solid portion of the lesions were used to represent each lesion, and the values of the histologic groups were compared.
  
  
  RESULTS
  The respective value of ADC for 12 malignant lymphomas, four other mesenchymal neoplasms, seven benign mesenchymal neoplasms, and two nonneoplastic lesions were as follows: 0.66 +/- 0.26, 1.26 +/- 0.50, 0.90 +/- 0.20, 1.87 +/- 0.48, 1.32 +/- 0.20 x 10(-3) mm2/second. The ADC value of the malignant lymphoma was significantly lower than that of the other malignant mesenchymal lesions, and was also lower than the ADC of the benign lesions. The ADC value of the malignant epithelial neoplasms was lower than that of the benign mesenchymal tumors. The ADC values of the malignant and benign lesions were 0.94 +/- 0.30 and 1.75 +/- 0.49 x 10(-3) mm2/second, respectively, which also demonstrated a significant difference.
  
  
  CONCLUSIONS
  ADC values calculated from EPDW MR images may provide useful information in the differential diagnosis of retroperitoneal masses.
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Nakayama
authors.forename: Kengo
authors.initials: K
authors.lastname: Yoshimitsu
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Irie
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Aibe
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Tajima
authors.forename: Kenji
authors.initials: K
authors.lastname: Shinozaki
authors.forename: Akihiro
authors.initials: A
authors.lastname: Nishie
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Asayama
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kakihara
authors.forename: Shuji
authors.initials: S
authors.lastname: Matsuura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Honda
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis*