title: [Vesicoureteric reflux in children: long-term results of endoscopic treatment by Macroplastique injection].
abstract: OBJECTIVE
  To evaluate the long-term efficacy (from the fifth year after injection and up to seven years) of endoscopic treatment by Macroplastique implant for vesicoureteric reflux (VUR) in children, sometimes associated with urological malformations or renal complications. The secondary objective was to evaluate the local tolerance of the Macroplastique implant and the development of any local (haematuria, stones, ureteric stasis) or distant complications.
  
  
  METHODS
  Retrospective analysis of the medical files of 389 patients, representing a total of 590 refluxing ureters treated by Macroplastique injection in eight different centres.
  
  
  RESULTS
  With a follow-up of 5 to 7 years, reflux had not recurred in 309 of the 389 cases, i.e. 79.4% of cases and no case of ureteric stricture was observed.
  
  
  CONCLUSIONS
  The good short-term results in terms of correction of reflux by Macroplastique injection and the very low morbidity are maintained with time. It therefore appears legitimate to propose endoscopic treatment of VUR by first-line Macroplastique injection instead of surgical ureteric reimplantation.
authors.affiliation: Service de Chirurgie Pédiatrique, Hôpital Edouard-Herriot, Lyon, France.
authors.forename: Hubert
authors.initials: H
authors.lastname: Dodat
authors.forename: Didier
authors.initials: D
authors.lastname: Aubert
authors.forename: Yves
authors.initials: Y
authors.lastname: Chavrier
authors.forename: Stephan
authors.initials: S
authors.lastname: Geiss
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Guys
authors.forename: Alain
authors.initials: A
authors.lastname: Lacombe
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Pierre
authors.forename: Valla
authors.initials: V
authors.lastname: Jean-Stéphane
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D015552:Injections, Intralesional; D008297:Male; D019736:Prostheses and Implants; D012189:Retrospective Studies; D013997:Time Factors; D014718:Vesico-Ureteral Reflux / Q000628:therapy*
vernacular_title: Reflux vésico-urétéral chez l'enfant: résultats à long terme du traitement endoscopique par injection de Macroplastique.