Diffusion MR findings in cyclosporin-A induced encephalopathy.
Cyclosporin encephalopathy is a well-known entity, which is clinically characterized by altered mental status, vision problems, focal neurological deficits and seizures. The exact pathophysiology of the cyclosporin encephalopathy has not yet been defined. We report the diffusion-weighted MR imaging and proton MR spectroscopy findings in a case of cyclosporin encephalopathy. The white-matter lesions with reversible restricted diffusion supported the hypothesis of reversible vasospasm induced by the cyclosporin.
Aydin
Kubilay
K
Neuroradiology Division, Department of Radiology, Istanbul Medical School, Istanbul University, Istanbul, Turkey.
Donmez
Fuldem
F
Tuzun
Umit
U
Minareci
Ozenc
O
Atamer
Tanju
T
D000328:Adult; D001921:Brain / Q000378:metabolism / Q000473:pathology; D001927:Brain Diseases / Q000139:chemically induced* / Q000175:diagnosis*; D016572:Cyclosporine / Q000037:antagonists & inhibitors*; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D007166:Immunosuppressive Agents / Q000037:antagonists & inhibitors*; D009682:Magnetic Resonance Spectroscopy; D008297:Male
D007166:Immunosuppressive Agents; D016572:Cyclosporine