title: Isolation, crystal and solution structure determination, and biosynthesis of tubulysins--powerful inhibitors of tubulin polymerization from myxobacteria.
authors.affiliation: Bereich Naturstoffe, Gesellschaft für Biotechnologische Forschung mbH, Mascheroder Weg 1, 38124 Braunschweig, Germany.
authors.forename: Heinrich
authors.initials: H
authors.lastname: Steinmetz
authors.forename: Nicole
authors.initials: N
authors.lastname: Glaser
authors.forename: Eberhardt
authors.initials: E
authors.lastname: Herdtweck
authors.forename: Florenz
authors.initials: F
authors.lastname: Sasse
authors.forename: Hans
authors.initials: H
authors.lastname: Reichenbach
authors.forename: Gerhard
authors.initials: G
authors.lastname: Höfle
mesh_terms: D001704:Biopolymers / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D003460:Crystallization; D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009231:Myxococcales / Q000737:chemistry*; D009842:Oligopeptides / Q000096:biosynthesis* / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D012996:Solutions; D014404:Tubulin / Q000378:metabolism*; D050257:Tubulin Modulators
chemical_list: D001704:Biopolymers; D009842:Oligopeptides; D012996:Solutions; D014404:Tubulin; D050257:Tubulin Modulators; C502386:tubulysin D