Advanced method for assignment of absolute configuration utilizing an induced CD and computational technique: its application to natural products possessing a secondary alcohol.
A modified procedure for determining absolute configurations using an induced CD method and molecular mechanics calculations is disclosed. The practical usefulness of the present technique was demonstrated by its application to a few natural products.
Hosoi
Shinzo
S
School of Pharmaceutical Sciences, Kyushu University of Health and Welfare, 1714-1 Yoshino-cho, Nobeoka 882-8508, Japan. shosoi@phoenix.ac.jp
Serata
Jun
J
Kiuchi
Fumiyuki
F
Sakushima
Akiyo
A
Ohta
Tomihisa
T
D001688:Biological Products / Q000737:chemistry*; D002942:Circular Dichroism / Q000379:methods*; D019295:Computational Biology; D008958:Models, Molecular; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D019666:Rubiaceae / Q000737:chemistry
D001688:Biological Products