First example of ring expansion of activated quinolines and isoquinolines: novel benzoazepines.
Activated quinoline and isoquinoline undergo unexpected ring expansion by diazocarbonyl compounds via C-C insertion in the presence of 5 mol% of copper triflate to produce ethyl 1H-benzo[b]azepine-1-carboxylate and ethyl 3H-benzo[d]azepine-3-carboxylate, respectively, in excellent yields with a high degree of selectivity
Yadav
J S
JS
Division of Organic Chemistry, Hyderabad-500 007, India. yadavpub@iict.res.in
Reddy
B V Subba
BV
Gupta
Manoj Kumar
MK
Prabhakar
A
A
Jagadeesh
B
B