title: Routine intravascular ultrasound scanning guidance of coronary stenting is not associated with improved clinical outcomes.
abstract: OBJECTIVE
  The purpose of the current study was to determine whether there is any incremental benefit to routine intravascular ultrasound (IVUS) guidance of percutaneous coronary intervention.
  
  
  RESULTS
  We compared the outcome of 796 patients who underwent an IVUS study (IVUS group) during the index stent procedure with 8274 patients who did not have an IVUS study (angiography group). The primary end point was the composite end point of death, myocardial infarction, or ischemia-driven target vessel revascularization within 9 months of the index stent procedure. There were statistically significant differences in multiple procedural characteristics. Most importantly, those patients who underwent an IVUS study had a larger postprocedural minimal lumen diameter and smaller postprocedural percent diameter stenosis. However, there was no significant difference between the IVUS group and the angiography group with respect to the primary end point (RR 1.10, 95% CI 0.91, 1.32) or any of the individual clinical end points. Adjustment for multiple clinical and procedural characteristics did not significantly alter these findings.
  
  
  CONCLUSIONS
  These data suggest that the routine performance of IVUS during stent placement influences the performance of the procedure, as judged by differences in procedural characteristics, but does not improve clinical outcome at 9 months.
authors.affiliation: Division of Cardiovascular Medicine and Department of Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA.
authors.forename: James L
authors.initials: JL
authors.lastname: Orford
authors.forename: Ali E
authors.initials: AE
authors.lastname: Denktas
authors.forename: Brent A
authors.initials: BA
authors.lastname: Williams
authors.forename: Panayotis
authors.initials: P
authors.lastname: Fasseas
authors.forename: James T
authors.initials: JT
authors.lastname: Willerson
authors.forename: Peter B
authors.initials: PB
authors.lastname: Berger
authors.forename: David R
authors.initials: DR
authors.lastname: Holmes
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D017023:Coronary Angiography; D003327:Coronary Disease / Q000401:mortality / Q000628:therapy*; D018572:Disease-Free Survival; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction; D012306:Risk; D015607:Stents; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional