title: HPLC identification of oversulphated chondroitin as the major glycosaminoglycan of human tonsils.
abstract: The glycosaminoglycans of human nasopharyngeal and palatine tonsils, obtained after surgical dissection due to tonsillitis, were isolated and characterized by means of enzyme susceptibility and HPLC. Chondroitin/dermatan sulphate were the major glycosaminoglycans identified. A large proportion of this glycosaminoglycan was made up of oversulphated structures, namely DeltaDi-di(4,6)S, which were found mainly in invertebrate tissues and in mast cells.
authors.affiliation: Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras 265 00, Greece.
authors.forename: I E
authors.initials: IE
authors.lastname: Triantaphyllidou
authors.forename: N S
authors.initials: NS
authors.lastname: Mastronikolis
authors.forename: Th A
authors.initials: TA
authors.lastname: Papadas
authors.forename: D H
authors.initials: DH
authors.lastname: Vynios
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002809:Chondroitin Sulfates / Q000032:analysis*; D002850:Chromatography, Gel / Q000379:methods; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D006025:Glycosaminoglycans / Q000032:analysis*; D006801:Humans; D014066:Palatine Tonsil / Q000737:chemistry*
chemical_list: D006025:Glycosaminoglycans; D002809:Chondroitin Sulfates