Screening for antibacterial activity in 72 species of wood-colonizing fungi by the Vibrio fisheri bioluminescence method.
Resistance of pathogenic bacteria to antibiotics leads scientists to discover new antibacterial drugs. Ninety samples of wood-colonizing fungi were cultivated on agar plates, and their extracts tested for antibacterial activity using the Vibrio fischeri bioluminescence test. Two fungi species, Serpula lacrymans and Nectria vilior, were found to be a potential new source of thermostable antibiotics. Vibrio fischeri bioluminescence test was found to be a useful method for antibacterial activity screening from the samples of natural origin.
Zrimec
Maja Berden
MB
Institute Bion, Stegne 21, SI--1000 Ljubljana, Slovenia.
Zrimec
Alexis
A
Slanc
Petra
P
Kac
Javor
J
Kreft
Samo
S
D048908:Aliivibrio fischeri / Q000187:drug effects* / Q000235:genetics / Q000502:physiology; D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D001487:Basidiomycota / Q000302:isolation & purification / Q000378:metabolism; D005658:Fungi / Q000302:isolation & purification / Q000378:metabolism*; D017930:Genes, Reporter; D006999:Hypocreales / Q000302:isolation & purification / Q000378:metabolism; D008826:Microbial Sensitivity Tests; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*; D014934:Wood
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; C085427:LuxI protein, Bacteria; D014157:Transcription Factors