title: Micropapillary variant of transitional cell carcinoma of the bladder.
abstract: A 77-year-old man visited the Kobe City General Hospital complaining of macroscopic hematuria. A computed tomography scan found a bladder tumor with left iliac and para-aortic lymph node metastasis. Two courses of cisplatin, cyclophosphamide and doxorubicin chemotherapy resulted in a minimal response. Radical cystectomy and a retroperitoneal lymph node dissection with bilateral ureterocutaneostomy reconstruction were then performed. A pathological examination revealed a micropapillary variant of transitional cell carcinoma (Grade 3, pT1pN2M1). The patient died of pelvic recurrence 7 months after the initiation of chemotherapy. Peritonitis carcinomatosa and lung metastases were observed at autopsy.
authors.affiliation: Department of Urology, Kobe City General Hospital, Japan. sugifly@oak.ocn.ne.jp
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Sugino
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Negoro
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Iwamura
authors.forename: Seiji
authors.initials: S
authors.lastname: Moroi
authors.forename: Hiroya
authors.initials: H
authors.lastname: Oka
authors.forename: Mutsushi
authors.initials: M
authors.lastname: Kawakita
authors.forename: Keisuke
authors.initials: K
authors.lastname: Hanioka
authors.forename: Hideo
authors.initials: H
authors.lastname: Takeuchi
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002295:Carcinoma, Transitional Cell / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D017809:Fatal Outcome; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D009364:Neoplasm Recurrence, Local; D019651:Plastic Surgery Procedures; D014057:Tomography, X-Ray Computed; D001749:Urinary Bladder Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery