Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo.
Hollenberg
Morley D
MD
Mucosal Inflammation Research Groups, Canadian Institutes of Health Research, Proteases and Inflammation Network (PAIN), Faculty of Medicine, University of Calgary, Calgary, AB, Canada T2N 4N1. mhollenb@ucalgary.ca
Saifeddine
Mahmoud
M
Sandhu
Sabrina
S
Houle
Steeve
S
Vergnolle
Nathalie
N
D000595:Amino Acid Sequence / Q000235:genetics; D000818:Animals; D004305:Dose-Response Relationship, Drug; D066298:In Vitro Techniques; D007249:Inflammation / Q000139:chemically induced* / Q000235:genetics; D008024:Ligands; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects / Q000502:physiology; D010446:Peptide Fragments / Q000235:genetics / Q000494:pharmacology* / Q000633:toxicity; D051381:Rats; D017207:Rats, Sprague-Dawley; D017208:Rats, Wistar; D018179:Receptors, Thrombin / Q000819:agonists* / Q000235:genetics / Q000502:physiology; D014664:Vasodilation / Q000187:drug effects / Q000502:physiology
D008024:Ligands; D010446:Peptide Fragments; D018179:Receptors, Thrombin; C112908:protease-activated receptor 4