title: Development and automation of a 384-well cell fusion assay to identify inhibitors of CCR5/CD4-mediated HIV virus entry.
authors.affiliation: Laboratory Automation Group, Pfizer Global Research and Development, Kent, UK.
authors.forename: Joe
authors.initials: J
authors.lastname: Bradley
authors.forename: Jasween
authors.initials: J
authors.lastname: Gill
authors.forename: Francois
authors.initials: F
authors.lastname: Bertelli
authors.forename: Sara
authors.initials: S
authors.lastname: Letafat
authors.forename: Romu
authors.initials: R
authors.lastname: Corbau
authors.forename: Paul
authors.initials: P
authors.lastname: Hayter
authors.forename: Paula
authors.initials: P
authors.lastname: Harrison
authors.forename: Andy
authors.initials: A
authors.lastname: Tee
authors.forename: Wilma
authors.initials: W
authors.lastname: Keighley
authors.forename: Manos
authors.initials: M
authors.lastname: Perros
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Ciaramella
authors.forename: Andreas
authors.initials: A
authors.lastname: Sewing
authors.forename: Christine
authors.initials: C
authors.lastname: Williams
mesh_terms: D000818:Animals; D001665:Binding Sites; D001681:Biological Assay / Q000379:methods*; D065100:CCR5 Receptor Antagonists; D015704:CD4 Antigens / Q000378:metabolism*; D016466:CHO Cells; D002459:Cell Fusion; D002460:Cell Line; D006224:Cricetinae; D003412:Cricetulus; D015696:Gene Products, tat / Q000378:metabolism; D019302:HIV Envelope Protein gp160 / Q000378:metabolism; D023581:HIV Fusion Inhibitors / Q000032:analysis* / Q000494:pharmacology; D015497:HIV-1 / Q000378:metabolism*; D006367:HeLa Cells; D006801:Humans; D010446:Peptide Fragments / Q000378:metabolism; D019713:Receptors, CCR5 / Q000378:metabolism*; D012371:Robotics / Q000295:instrumentation / Q000379:methods*; D013997:Time Factors; D014162:Transfection; D001616:beta-Galactosidase / Q000378:metabolism; D054322:tat Gene Products, Human Immunodeficiency Virus
chemical_list: D065100:CCR5 Receptor Antagonists; D015704:CD4 Antigens; D015696:Gene Products, tat; D019302:HIV Envelope Protein gp160; D023581:HIV Fusion Inhibitors; D010446:Peptide Fragments; D019713:Receptors, CCR5; D054322:tat Gene Products, Human Immunodeficiency Virus; C415751:tat peptide (1-9), Human immunodeficiency virus 1; D001616:beta-Galactosidase