Recombinant human antibodies against aldehyde-modified apolipoprotein B-100 peptide sequences inhibit atherosclerosis.
Schiopu
Alexandru
A
Department of Medicine, Malmö University Hospital, Lund University, Malmö, Sweden. Alexandru.Schiopu@medforsk.mas.lu.se.
Bengtsson
Jenny
J
Söderberg
Ingrid
I
Janciauskiene
Sabina
S
Lindgren
Stefan
S
Ares
Mikko P S
MP
Shah
Prediman K
PK
Carlsson
Roland
R
Nilsson
Jan
J
Fredrikson
Gunilla Nordin
GN
D000595:Amino Acid Sequence; D000818:Animals; D053299:Apolipoprotein B-100; D001055:Apolipoproteins B / Q000737:chemistry / Q000276:immunology*; D001057:Apolipoproteins E / Q000172:deficiency / Q000235:genetics; D001161:Arteriosclerosis / Q000473:pathology / Q000517:prevention & control*; D004353:Drug Evaluation, Preclinical; D006801:Humans; D007116:Immunization, Passive; D007128:Immunoglobulin Fragments / Q000235:genetics / Q000276:immunology / Q000627:therapeutic use*; D007074:Immunoglobulin G / Q000235:genetics / Q000276:immunology / Q000627:therapeutic use*; D007135:Immunoglobulin Variable Region / Q000235:genetics / Q000276:immunology / Q000627:therapeutic use*; D007146:Immunoglobulin lambda-Chains / Q000235:genetics; D008077:Lipoproteins, LDL / Q000378:metabolism* / Q000494:pharmacology; D008264:Macrophages / Q000473:pathology; D008297:Male; D008315:Malondialdehyde / Q000737:chemistry / Q000276:immunology; D051379:Mice; D018345:Mice, Knockout; D008969:Molecular Sequence Data; D009000:Monocytes / Q000378:metabolism; D010446:Peptide Fragments / Q000737:chemistry / Q000276:immunology; D011993:Recombinant Fusion Proteins / Q000276:immunology / Q000627:therapeutic use
D053299:Apolipoprotein B-100; D001055:Apolipoproteins B; D001057:Apolipoproteins E; D007128:Immunoglobulin Fragments; D007074:Immunoglobulin G; D007135:Immunoglobulin Variable Region; D007146:Immunoglobulin lambda-Chains; D008077:Lipoproteins, LDL; D010446:Peptide Fragments; D011993:Recombinant Fusion Proteins; C099252:oxidized low density lipoprotein; D008315:Malondialdehyde