title: Influence of glutathione depletion on plasma membrane cholesterol esterification and on Tc-99m-sestamibi and Tc-99m-tetrofosmin uptakes: a comparative study in sensitive U-87-MG and multidrug-resistant MRP1 human glioma cells.
authors.affiliation: Laboratory of Biophysics Research Group EA 3063, Faculty of Medicine, Saint-Etienne, France.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Le Jeune
authors.forename: Nathalie
authors.initials: N
authors.lastname: Perek
authors.forename: Delphine
authors.initials: D
authors.lastname: Denoyer
authors.forename: Francis
authors.initials: F
authors.lastname: Dubois
mesh_terms: D001692:Biological Transport; D019328:Buthionine Sulfoximine / Q000494:pharmacology; D045744:Cell Line, Tumor; D002788:Cholesterol Esters / Q000378:metabolism*; D018432:Drug Resistance, Multiple; D019008:Drug Resistance, Neoplasm; D005910:Glioma / Q000188:drug therapy* / Q000378:metabolism; D005978:Glutathione / Q000032:analysis*; D006801:Humans; D008563:Membrane Lipids / Q000032:analysis / Q000378:metabolism*; D027425:ATP-Binding Cassette, Sub-Family C Proteins / Q000032:analysis*; D009943:Organophosphorus Compounds / Q000493:pharmacokinetics*; D015609:Organotechnetium Compounds / Q000493:pharmacokinetics*; D017256:Technetium Tc 99m Sestamibi / Q000493:pharmacokinetics*
chemical_list: D019328:Buthionine Sulfoximine; D002788:Cholesterol Esters; D005978:Glutathione; D008563:Membrane Lipids; D027425:ATP-Binding Cassette, Sub-Family C Proteins; D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D017256:Technetium Tc 99m Sestamibi; C078700:technetium tc-99m tetrofosmin; C421109:multidrug resistance-associated protein 1