MAPK recruitment by beta-amyloid in organotypic hippocampal slice cultures depends on physical state and exposure time.
Bell
Karen A
KA
Division of Neuroscience, Baylor College of Medicine, Houston, Texas, USA.
O'Riordan
Kenneth J
KJ
Sweatt
J David
JD
Dineley
Kelly T
KT
D016229:Amyloid beta-Peptides / Q000494:pharmacology*; D000818:Animals; D017868:Cyclic AMP-Dependent Protein Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism; D004789:Enzyme Activation / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006624:Hippocampus / Q000187:drug effects* / Q000378:metabolism*; D066298:In Vitro Techniques; D046911:Macromolecular Substances; D020928:Mitogen-Activated Protein Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D009538:Nicotine / Q000494:pharmacology; D010446:Peptide Fragments / Q000494:pharmacology*; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D000081082:Phosphoinositide-3 Kinase Inhibitors; D051381:Rats; D017207:Rats, Sprague-Dawley; D011978:Receptors, Nicotinic / Q000187:drug effects / Q000378:metabolism; D038744:Ribosomal Protein S6 Kinases, 90-kDa / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects; D013997:Time Factors; D064569:alpha7 Nicotinic Acetylcholine Receptor
D016229:Amyloid beta-Peptides; D017868:Cyclic AMP-Dependent Protein Kinases; D004791:Enzyme Inhibitors; D046911:Macromolecular Substances; D020928:Mitogen-Activated Protein Kinases; D009538:Nicotine; D010446:Peptide Fragments; D019869:Phosphatidylinositol 3-Kinases; D000081082:Phosphoinositide-3 Kinase Inhibitors; D011978:Receptors, Nicotinic; D038744:Ribosomal Protein S6 Kinases, 90-kDa; D064569:alpha7 Nicotinic Acetylcholine Receptor; C579165:Chrna7 protein, rat; C078592:amyloid beta-protein (1-40); C075222:amyloid beta-protein (1-42)