Rational design of an L-histidine-derived minimal artificial acylase for the kinetic resolution of racemic alcohols.
Ishihara
Kazuaki
K
Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa, Nagoya 464-8603, Japan. ishihara@cc.nagoya-u.ac.jp
Kosugi
Yuji
Y
Akakura
Matsujiro
M
D000215:Acylation; D000438:Alcohols / Q000737:chemistry / Q000302:isolation & purification*; D000581:Amidohydrolases / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D006639:Histidine / Q000031:analogs & derivatives* / Q000737:chemistry; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry; D007700:Kinetics; D017433:Protein Structure, Secondary; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism
C417980:4-(dimethylamine)pyridine; D000438:Alcohols; D007093:Imidazoles; D011725:Pyridines; D006639:Histidine; D000581:Amidohydrolases; C019665:amidase