The P23T cataract mutation causes loss of solubility of folded gammaD-crystallin.
Evans
P
P
Department of Crystallography, Birkbeck College, Malet Street, London WC1E 7HX, UK.
Wyatt
K
K
Wistow
G J
GJ
Bateman
O A
OA
Wallace
B A
BA
Slingsby
C
C
D000595:Amino Acid Sequence; D000818:Animals; D002386:Cataract / Q000151:congenital / Q000235:genetics* / Q000378:metabolism; D002942:Circular Dichroism; D019791:Guanidine / Q000378:metabolism; D006801:Humans; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009154:Mutation; D011489:Protein Denaturation; D017510:Protein Folding; D017433:Protein Structure, Secondary; D016415:Sequence Alignment; D012995:Solubility; D038222:gamma-Crystallins / Q000737:chemistry* / Q000235:genetics*
D038222:gamma-Crystallins; D019791:Guanidine