Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage.
Lee
Daekee
D
Department of Genetics, CB#7264, University of North Carolina, Chapel Hill, NC 27599, USA.
Pearsall
R Scott
RS
Das
Sanjoy
S
Dey
Sudhansu K
SK
Godfrey
Virginia L
VL
Threadgill
David W
DW
D000818:Animals; D001835:Body Weight; D002460:Cell Line; D003106:Colon / Q000033:anatomy & histology / Q000473:pathology; D016264:Dextran Sulfate / Q000008:administration & dosage / Q000494:pharmacology; D004195:Disease Models, Animal; D004815:Epidermal Growth Factor / Q000235:genetics* / Q000378:metabolism*; D066260:Epiregulin; D004847:Epithelial Cells / Q000166:cytology / Q000378:metabolism; D018390:Gene Targeting; D017930:Genes, Reporter; D007413:Intestinal Mucosa / Q000033:anatomy & histology / Q000187:drug effects / Q000473:pathology*; D007414:Intestinal Neoplasms / Q000378:metabolism* / Q000473:pathology; D008115:Liver Regeneration / Q000502:physiology; D008297:Male; D051379:Mice; D018345:Mice, Knockout; D014018:Tissue Distribution
D066260:Epiregulin; C587881:Ereg protein, mouse; D004815:Epidermal Growth Factor; D016264:Dextran Sulfate