Methotrexate inhibits the glyoxalase system in vivo in children with acute lymphoid leukaemia.
Bartyik
Katalin
K
Department of Paediatrics, Albert Szent-Gyorgyi Medical School, University of Szeged, Koranyi Fasor 14-15, H-6720 Szeged, Hungary.
Turi
Sandor
S
Orosz
Ferenc
F
Karg
Eszter
E
D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D004791:Enzyme Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007791:Lactoylglutathione Lyase / Q000037:antagonists & inhibitors*; D008297:Male; D008727:Methotrexate / Q000494:pharmacology / Q000627:therapeutic use*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000201:enzymology*
D000964:Antimetabolites, Antineoplastic; D004791:Enzyme Inhibitors; D007791:Lactoylglutathione Lyase; D008727:Methotrexate