Human cytomegalovirus infection induces rapamycin-insensitive phosphorylation of downstream effectors of mTOR kinase.
Kudchodkar
Sagar B
SB
Department of Cancer Biology, Abramson Family Cancer Research Institute, 421 Curie Blvd., University of Pennsylvania, Philadelphia, PA 19104-6142, USA.
Yu
Yongjun
Y
Maguire
Tobi G
TG
Alwine
James C
JC
D002478:Cells, Cultured; D003587:Cytomegalovirus / Q000472:pathogenicity*; D039603:Eukaryotic Initiation Factor-4G / Q000378:metabolism*; D039642:Eukaryotic Initiation Factors / Q000378:metabolism*; D005347:Fibroblasts / Q000821:virology; D006801:Humans; D000860:Hypoxia; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D000081082:Phosphoinositide-3 Kinase Inhibitors; D010766:Phosphorylation / Q000187:drug effects; D011494:Protein Kinases / Q000378:metabolism*; D015398:Signal Transduction; D020123:Sirolimus / Q000494:pharmacology*; D058570:TOR Serine-Threonine Kinases; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism
D039603:Eukaryotic Initiation Factor-4G; D039642:Eukaryotic Initiation Factors; D019869:Phosphatidylinositol 3-Kinases; D000081082:Phosphoinositide-3 Kinase Inhibitors; D011494:Protein Kinases; D020123:Sirolimus; D058570:TOR Serine-Threonine Kinases; D014764:Viral Proteins; C546842:MTOR protein, human