title: Omeprazole treatment of Korean patients: effects on gastric pH and gastrin release in relation to CYP2C19 geno- and phenotypes.
authors.affiliation: Department of Laboratory Medicine, Division of Clinical Pharmacology, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden. keunroh@inha.ac.kr
authors.forename: Hyung-Keun
authors.initials: HK
authors.lastname: Roh
authors.forename: Pum-Soo
authors.initials: PS
authors.lastname: Kim
authors.forename: Don-Haeng
authors.initials: DH
authors.lastname: Lee
authors.forename: Gunnel
authors.initials: G
authors.lastname: Tybring
authors.forename: Mohamed
authors.initials: M
authors.lastname: Sagar
authors.forename: Chang-Shin
authors.initials: CS
authors.lastname: Park
authors.forename: Rein
authors.initials: R
authors.lastname: Seensalu
authors.forename: Leif
authors.initials: L
authors.lastname: Bertilsson
mesh_terms: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000328:Adult; D000368:Aged; D000897:Anti-Ulcer Agents / Q000097:blood / Q000493:pharmacokinetics / Q000627:therapeutic use*; D019540:Area Under Curve; D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics*; D065731:Cytochrome P-450 CYP2C19; D005260:Female; D005745:Gastric Acidity Determination; D005755:Gastrins / Q000097:blood / Q000378:metabolism*; D005838:Genotype; D006801:Humans; D006863:Hydrogen-Ion Concentration / Q000187:drug effects; D007723:Korea; D008297:Male; D008875:Middle Aged; D006899:Mixed Function Oxygenases / Q000235:genetics*; D009853:Omeprazole / Q000031:analogs & derivatives* / Q000097:blood / Q000493:pharmacokinetics / Q000627:therapeutic use*; D010641:Phenotype; D013272:Stomach Diseases / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism
chemical_list: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000897:Anti-Ulcer Agents; D005755:Gastrins; C040450:omeprazole sulfone; C049963:5-hydroxymethylomeprazole; D006899:Mixed Function Oxygenases; D001189:Aryl Hydrocarbon Hydroxylases; C045793:CYP2C19 protein, human; D065731:Cytochrome P-450 CYP2C19; D009853:Omeprazole