Effects of two familial hypertrophic cardiomyopathy mutations in alpha-tropomyosin, Asp175Asn and Glu180Gly, on the thermal unfolding of actin-bound tropomyosin.
Kremneva
Elena
E
A. N. Bach Institute of Biochemistry, Russian Academy of Sciences, Moscow 119071, Russia.
Boussouf
Sabrina
S
Nikolaeva
Olga
O
Maytum
Robin
R
Geeves
Michael A
MA
Levitsky
Dmitrii I
DI
D000199:Actins / Q000737:chemistry*; D019943:Amino Acid Substitution; D001665:Binding Sites; D024741:Cardiomyopathy, Hypertrophic, Familial / Q000235:genetics* / Q000378:metabolism*; D016297:Mutagenesis, Site-Directed; D009154:Mutation; D011485:Protein Binding; D011489:Protein Denaturation; D017510:Protein Folding; D013329:Structure-Activity Relationship; D013696:Temperature; D014335:Tropomyosin / Q000737:chemistry* / Q000235:genetics
D000199:Actins; D014335:Tropomyosin