title: Successful detection of (anti-)androgenic and aromatase inhibitors in pre-spawning adult fathead minnows (Pimephales promelas) using easily measured endpoints of sexual development.
authors.affiliation: AstraZeneca Global Safety, Health and Environment, Brixham Environmental Laboratory, Freshwater Quarry, Brixham, Devon TQ5 8BA, UK. grace.panter@brixham.astrazeneca.com
authors.forename: G H
authors.initials: GH
authors.lastname: Panter
authors.forename: T H
authors.initials: TH
authors.lastname: Hutchinson
authors.forename: K S
authors.initials: KS
authors.lastname: Hurd
authors.forename: A
authors.initials: A
authors.lastname: Sherren
authors.forename: R D
authors.initials: RD
authors.lastname: Stanley
authors.forename: C R
authors.initials: CR
authors.lastname: Tyler
mesh_terms: D000704:Analysis of Variance; D000726:Androgen Antagonists / Q000032:analysis* / Q000633:toxicity; D000728:Androgens / Q000032:analysis / Q000633:toxicity; D000818:Animals; D047072:Aromatase Inhibitors / Q000032:analysis* / Q000633:toxicity; D001681:Biological Assay / Q000379:methods; D015415:Biomarkers / Q000032:analysis; D003530:Cyprinidae / Q000097:blood*; D013196:Dihydrotestosterone / Q000032:analysis / Q000633:toxicity; D004305:Dose-Response Relationship, Drug; D004781:Environmental Exposure / Q000032:analysis; D004784:Environmental Monitoring / Q000379:methods*; D017316:Fadrozole / Q000032:analysis / Q000633:toxicity; D005260:Female; D005485:Flutamide / Q000032:analysis / Q000633:toxicity; D006066:Gonads / Q000187:drug effects; D008297:Male; D012737:Sex Factors; D046468:Sexual Development / Q000187:drug effects*; D014819:Vitellogenins / Q000097:blood* / Q000187:drug effects; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity
chemical_list: D000726:Androgen Antagonists; D000728:Androgens; D047072:Aromatase Inhibitors; D015415:Biomarkers; D014819:Vitellogenins; D014874:Water Pollutants, Chemical; D013196:Dihydrotestosterone; D005485:Flutamide; D017316:Fadrozole