Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: critical residues for DNA binding and hyperactivity in mammalian cells.
Yant
Stephen R
SR
Stanford University, Department of Pediatrics, 300 Pasteur Dr., Room G305, Stanford, CA 94305-5208, USA.
Park
Julie
J
Huang
Yong
Y
Mikkelsen
Jacob Giehm
JG
Kay
Mark A
MA
D000595:Amino Acid Sequence; D000818:Animals; D004247:DNA / Q000378:metabolism*; D004252:DNA Mutational Analysis; D004251:DNA Transposable Elements; D006367:HeLa Cells; D006801:Humans; D051379:Mice; D008810:Mice, Inbred C57BL; D016513:Mice, SCID; D008969:Molecular Sequence Data; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D019895:Transposases / Q000235:genetics* / Q000378:metabolism*
D004251:DNA Transposable Elements; D004247:DNA; D019895:Transposases; C494471:sleeping beauty transposase, human