Vitamin C inhibits hypoxia-induced damage and apoptotic signaling pathways in cardiomyocytes and ischemic hearts.
Guaiquil
Victor H
VH
Center for Cardiovascular and Muscle Research, Department of Anatomy and Cell Biology, State University of New York, Downstate Medical Center, Brooklyn, NY 11023, USA.
Golde
David W
DW
Beckles
Daniel L
DL
Mascareno
Eduardo J
EJ
Siddiqui
M A Q
MA
D000818:Animals; D017209:Apoptosis / Q000187:drug effects / Q000502:physiology*; D001205:Ascorbic Acid / Q000494:pharmacology*; D015687:Cell Hypoxia / Q000187:drug effects*; D003683:Dehydroascorbic Acid / Q000378:metabolism; D004195:Disease Models, Animal; D006321:Heart / Q000187:drug effects / Q000502:physiology*; D000860:Hypoxia / Q000517:prevention & control*; D032342:Muscle Cells / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D017202:Myocardial Ischemia / Q000473:pathology / Q000517:prevention & control*; D009206:Myocardium / Q000166:cytology; D051381:Rats; D017207:Rats, Sprague-Dawley; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology*
D001205:Ascorbic Acid; D003683:Dehydroascorbic Acid