title: Ubiquitin-dependent degradation of Id1 and Id3 is mediated by the COP9 signalosome.
authors.affiliation: Department of Surgery, Division of Molecular Biology, Charité, Universitätsmedizin Berlin, Monbijoustrasse 2, D-10117, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Berse
authors.forename: Mangkey
authors.initials: M
authors.lastname: Bounpheng
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Huang
authors.forename: Barbara
authors.initials: B
authors.lastname: Christy
authors.forename: Christian
authors.initials: C
authors.lastname: Pollmann
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Dubiel
mesh_terms: D000818:Animals; D000075686:COP9 Signalosome Complex; D047390:Casein Kinase II; D002460:Cell Line; D003546:Cysteine Endopeptidases / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000378:metabolism; D006801:Humans; D051798:Inhibitor of Differentiation Protein 1; D051796:Inhibitor of Differentiation Proteins; D008666:Metalloendopeptidases / Q000378:metabolism; D051379:Mice; D008969:Molecular Sequence Data; D009097:Multienzyme Complexes / Q000378:metabolism; D046912:Multiprotein Complexes; D009363:Neoplasm Proteins / Q000235:genetics / Q000378:metabolism*; D010447:Peptide Hydrolases; D010766:Phosphorylation; D046988:Proteasome Endopeptidase Complex; D011485:Protein Binding; D011493:Protein Kinase C / Q000037:antagonists & inhibitors / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism; D011506:Proteins / Q000378:metabolism*; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism; D012097:Repressor Proteins / Q000235:genetics / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*; D020798:Two-Hybrid System Techniques; D025801:Ubiquitin / Q000378:metabolism*
chemical_list: C466088:COPS7A protein, human; D004791:Enzyme Inhibitors; C497453:ID1 protein, human; C497455:Idb1 protein, mouse; D051798:Inhibitor of Differentiation Protein 1; D051796:Inhibitor of Differentiation Proteins; D009097:Multienzyme Complexes; D046912:Multiprotein Complexes; D009363:Neoplasm Proteins; D011506:Proteins; D011993:Recombinant Fusion Proteins; D012097:Repressor Proteins; D029701:Saccharomyces cerevisiae Proteins; D014157:Transcription Factors; D025801:Ubiquitin; C075640:ID3 protein, human; C089212:protein kinase D; D047390:Casein Kinase II; D017346:Protein Serine-Threonine Kinases; D011493:Protein Kinase C; D010447:Peptide Hydrolases; D000075686:COP9 Signalosome Complex; D003546:Cysteine Endopeptidases; D008666:Metalloendopeptidases; C468276:Rri1 protein, S cerevisiae; D046988:Proteasome Endopeptidase Complex