Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway.
Powles
Thomas
T
New Drug Study Group, St. Bartholomew's Hospital, London, United Kingdom.
te Poele
Robert
R
Shamash
Jonathan
J
Chaplin
Tracy
T
Propper
David
D
Joel
Simon
S
Oliver
Tim
T
Liu
Wai Man
WM
D002186:Cannabinoids / Q000633:toxicity*; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects*; D013759:Dronabinol / Q000633:toxicity*; D005786:Gene Expression Regulation / Q000187:drug effects; D018922:HL-60 Cells; D006801:Humans; D020935:MAP Kinase Signaling System / Q000187:drug effects / Q000502:physiology*; D043884:Receptor, Cannabinoid, CB1 / Q000187:drug effects / Q000502:physiology*; D043885:Receptor, Cannabinoid, CB2 / Q000187:drug effects / Q000502:physiology*; D016159:Tumor Suppressor Protein p53 / Q000187:drug effects / Q000378:metabolism
D002186:Cannabinoids; D043884:Receptor, Cannabinoid, CB1; D043885:Receptor, Cannabinoid, CB2; D016159:Tumor Suppressor Protein p53; D013759:Dronabinol