The role of structural factors in the kinetics of cellular uptake of pyrazoloacridines and pyrazolopyrimidoacridines: implications for overcoming multidrug resistance towards leukaemia K562/DOX cells.
Tarasiuk
Jolanta
J
Department of Pharmaceutical Technology and Biochemistry, Technical University of Gdańsk, Poland. tarasiuk@univ.szczecin.pl
Majewska
Ewelina
E
Seksek
Olivier
O
Rogacka
Dorota
D
Antonini
Ippolito
I
Garnier-Suillerot
Arlette
A
Borowski
Edward
E
D000166:Acridines / Q000494:pharmacology*; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D004317:Doxorubicin / Q000494:pharmacology; D018432:Drug Resistance, Multiple; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D020014:K562 Cells; D007700:Kinetics; D007938:Leukemia / Q000473:pathology; D051379:Mice; D041681:NIH 3T3 Cells; D011720:Pyrazoles / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
D000166:Acridines; D000970:Antineoplastic Agents; D011720:Pyrazoles; D004317:Doxorubicin; C064541:NSC 366140