TLR2 and TLR4 stimulation differentially induce cytokine secretion in human neonatal, adult, and murine mononuclear cells.
Schaub
Bianca
B
Pulmonary and Critical Care Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Bellou
Abdelouahab
A
Gibbons
Fiona K
FK
Velasco
German
G
Campo
Monica
M
He
Hongzhen
H
Liang
Yurong
Y
Gillman
Matthew W
MW
Gold
Diane
D
Weiss
Scott T
ST
Perkins
David L
DL
Finn
Patricia W
PW
D000328:Adult; D000818:Animals; D006801:Humans; D007231:Infant, Newborn; D007371:Interferon-gamma / Q000378:metabolism*; D018793:Interleukin-13 / Q000378:metabolism*; D007963:Leukocytes, Mononuclear / Q000187:drug effects / Q000276:immunology*; D008050:Lipid A / Q000494:pharmacology; D008213:Lymphocyte Activation; D008562:Membrane Glycoproteins / Q000819:agonists*; D051379:Mice; D010457:Peptidoglycan / Q000494:pharmacology; D011956:Receptors, Cell Surface / Q000819:agonists*; D015398:Signal Transduction; D013154:Spleen / Q000166:cytology / Q000378:metabolism; D018417:Th1 Cells / Q000276:immunology; D018418:Th2 Cells / Q000276:immunology; D051195:Toll-Like Receptor 2; D051197:Toll-Like Receptor 4; D051193:Toll-Like Receptors
D018793:Interleukin-13; D008050:Lipid A; D008562:Membrane Glycoproteins; D010457:Peptidoglycan; D011956:Receptors, Cell Surface; C495342:TLR2 protein, human; C495345:TLR4 protein, human; D051195:Toll-Like Receptor 2; D051197:Toll-Like Receptor 4; D051193:Toll-Like Receptors; D007371:Interferon-gamma