Intraischaemic hypothermia reduces free radical production and protects against ischaemic insults in cultured hippocampal slices.
McManus
Terence
T
Division of Clinical Neurosciences, School of Medicine, Southampton University, Southampton, UK.
Sadgrove
Matthew
M
Pringle
Ashley K
AK
Chad
John E
JE
Sundstrom
Lars E
LE
D000818:Animals; D000831:Animals, Newborn; D002545:Brain Ischemia / Q000378:metabolism*; D015687:Cell Hypoxia / Q000502:physiology; D019610:Cytoprotection / Q000502:physiology; D018690:Excitatory Amino Acid Agonists / Q000494:pharmacology; D005456:Fluorescent Dyes; D005609:Free Radicals / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism; D006624:Hippocampus / Q000187:drug effects / Q000378:metabolism*; D007036:Hypothermia, Induced; D066298:In Vitro Techniques; D016202:N-Methylaspartate / Q000494:pharmacology; D009410:Nerve Degeneration / Q000517:prevention & control; D009474:Neurons / Q000187:drug effects / Q000378:metabolism; D009569:Nitric Oxide / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013481:Superoxides / Q000378:metabolism; D013696:Temperature; D013997:Time Factors
D018690:Excitatory Amino Acid Agonists; D005456:Fluorescent Dyes; D005609:Free Radicals; D013481:Superoxides; D009569:Nitric Oxide; D016202:N-Methylaspartate; D005947:Glucose