Melanoma heterogeneity: differential, invasive, metastatic properties and profiles of cathepsin B, D and L activities in subclones of the B16F10-NEX2 cell line.
Freitas
Zenilda F O
ZF
Experimental Oncology Unit (UNONEX), Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
Rodrigues
Elaine G
EG
Oliveira
Vitor
V
Carmona
Adriana K
AK
Travassos
Luiz R
LR
D000818:Animals; D000951:Antigens, Neoplasm / Q000096:biosynthesis; D002401:Cathepsin B / Q000378:metabolism; D002403:Cathepsins / Q000494:pharmacology; D045744:Cell Line, Tumor; D002465:Cell Movement; D002469:Cell Separation; D002470:Cell Survival; D003094:Collagen / Q000494:pharmacology; D003546:Cysteine Endopeptidases / Q000378:metabolism; D004338:Drug Combinations; D005434:Flow Cytometry; D006863:Hydrogen-Ion Concentration; D007797:Laminin / Q000494:pharmacology; D008545:Melanoma / Q000175:diagnosis* / Q000473:pathology*; D008546:Melanoma, Experimental / Q000473:pathology; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D010447:Peptide Hydrolases / Q000378:metabolism; D011509:Proteoglycans / Q000494:pharmacology; D012333:RNA, Messenger / Q000378:metabolism; D013997:Time Factors; D014407:Tumor Cells, Cultured
D000951:Antigens, Neoplasm; D004338:Drug Combinations; D007797:Laminin; D011509:Proteoglycans; D012333:RNA, Messenger; C059485:matrigel; D003094:Collagen; D002403:Cathepsins; D010447:Peptide Hydrolases; D003546:Cysteine Endopeptidases; D002401:Cathepsin B