Anabolism of amdoxovir: phosphorylation of dioxolane guanosine and its 5'-phosphates by mammalian phosphotransferases.
Feng
Joy Y
JY
Gilead Sciences, 4 University Place, 4611 University Drive, Durham, NC 27707, USA. joy.feng@gilead.com
Parker
William B
WB
Krajewski
Megan L
ML
Deville-Bonne
Dominique
D
Veron
Michel
M
Krishnan
Preethi
P
Cheng
Yung-Chi
YC
Borroto-Esoda
Katyna
K
D000998:Antiviral Agents; D004148:Dioxolanes / Q000378:metabolism*; D006151:Guanosine / Q000031:analogs & derivatives* / Q000378:metabolism*; D006160:Guanosine Triphosphate / Q000031:analogs & derivatives* / Q000378:metabolism*; D006801:Humans; D010766:Phosphorylation; D010770:Phosphotransferases / Q000378:metabolism*; D011684:Purine Nucleosides / Q000378:metabolism*; D014407:Tumor Cells, Cultured
D000998:Antiviral Agents; D004148:Dioxolanes; D011684:Purine Nucleosides; C098394:dioxolane guanosine; C475165:dioxolane guanosine 5'-triphosphate; D006151:Guanosine; C098393:amdoxovir; D006160:Guanosine Triphosphate; D010770:Phosphotransferases