Major human cytomegalovirus structural protein pp65 (ppUL83) prevents interferon response factor 3 activation in the interferon response.
Abate
Davide A
DA
Department of Microbiology and Immunology, D 347 Fairchild Science Bldg., Stanford University School of Medicine, Stanford, CA 94305-5124, USA.
Watanabe
Shinya
S
Mocarski
Edward S
ES
D002478:Cells, Cultured; D003587:Cytomegalovirus / Q000235:genetics / Q000472:pathogenicity*; D004268:DNA-Binding Proteins / Q000378:metabolism*; D005347:Fibroblasts / Q000821:virology; D005786:Gene Expression Regulation; D006801:Humans; D050838:Interferon Regulatory Factor-3; D007370:Interferon Type I / Q000378:metabolism; D020411:Oligonucleotide Array Sequence Analysis; D010750:Phosphoproteins / Q000235:genetics / Q000494:pharmacology*; D011506:Proteins / Q000235:genetics / Q000378:metabolism; D020543:Proteome; D014157:Transcription Factors / Q000378:metabolism*; D014763:Viral Matrix Proteins / Q000235:genetics / Q000494:pharmacology*
D004268:DNA-Binding Proteins; C494232:IRF3 protein, human; D050838:Interferon Regulatory Factor-3; D007370:Interferon Type I; D010750:Phosphoproteins; D011506:Proteins; D020543:Proteome; D014157:Transcription Factors; D014763:Viral Matrix Proteins; C065418:cytomegalovirus matrix protein 65kDa