title: N-acetylcysteine treatment normalizes serum tumor necrosis factor-alpha level and hinders the progression of cardiac injury in hypertensive rats.
authors.affiliation: Fédération de Cardiologie, Hôpital Henri Mondor, Créteil, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Bourraindeloup
authors.forename: Christophe
authors.initials: C
authors.lastname: Adamy
authors.forename: Gabriele
authors.initials: G
authors.lastname: Candiani
authors.forename: Michel
authors.initials: M
authors.lastname: Cailleret
authors.forename: Marie-Claude
authors.initials: MC
authors.lastname: Bourin
authors.forename: Thierry
authors.initials: T
authors.lastname: Badoual
authors.forename: Jin Bo
authors.initials: JB
authors.lastname: Su
authors.forename: Sylviane
authors.initials: S
authors.lastname: Adubeiro
authors.forename: Françoise
authors.initials: F
authors.lastname: Roudot-Thoraval
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Dubois-Rande
authors.forename: Luc
authors.initials: L
authors.lastname: Hittinger
authors.forename: Françoise
authors.initials: F
authors.lastname: Pecker
mesh_terms: D000111:Acetylcysteine / Q000494:pharmacology / Q000627:therapeutic use*; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology / Q000627:therapeutic use*; D003094:Collagen / Q000032:analysis; D018450:Disease Progression; D004353:Drug Evaluation, Preclinical; D005978:Glutathione / Q000172:deficiency / Q000502:physiology*; D006352:Heart Ventricles / Q000737:chemistry; D006973:Hypertension / Q000097:blood / Q000139:chemically induced / Q000150:complications / Q000188:drug therapy*; D008297:Male; D020778:Matrix Metalloproteinase 2 / Q000032:analysis; D020780:Matrix Metalloproteinase 9 / Q000032:analysis; D009200:Myocardial Contraction; D009206:Myocardium / Q000378:metabolism; D019331:NG-Nitroarginine Methyl Ester / Q000633:toxicity; D009569:Nitric Oxide / Q000096:biosynthesis; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors; D018384:Oxidative Stress / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D017673:Sodium Chloride, Dietary / Q000633:toxicity; D013108:Sphingomyelin Phosphodiesterase / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis*; D014463:Ultrasonography; D018487:Ventricular Dysfunction, Left / Q000097:blood / Q000000981:diagnostic imaging / Q000209:etiology / Q000517:prevention & control*; D020257:Ventricular Remodeling / Q000187:drug effects*
chemical_list: D000975:Antioxidants; D017673:Sodium Chloride, Dietary; D014409:Tumor Necrosis Factor-alpha; D009569:Nitric Oxide; D003094:Collagen; D019001:Nitric Oxide Synthase; D013108:Sphingomyelin Phosphodiesterase; D020778:Matrix Metalloproteinase 2; D020780:Matrix Metalloproteinase 9; D005978:Glutathione; D019331:NG-Nitroarginine Methyl Ester; D000111:Acetylcysteine