Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice.
Huo
Yuqing
Y
University of Virginia, Charlottesville, Va, USA. Yuqing@umn.edu.
Zhao
Lei
L
Hyman
Matthew Craig
MC
Shashkin
Pavel
P
Harry
Brian L
BL
Burcin
Tracy
T
Forlow
S Bradley
SB
Stark
Matthew A
MA
Smith
David F
DF
Clarke
Sean
S
Srinivasan
Suseela
S
Hedrick
Catherine C
CC
Praticò
Domenico
D
Witztum
Joseph L
JL
Nadler
Jerry L
JL
Funk
Colin D
CD
Ley
Klaus
K
D000818:Animals; D001057:Apolipoproteins E / Q000172:deficiency* / Q000235:genetics; D001092:Arachidonate 12-Lipoxygenase / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D001093:Arachidonate 15-Lipoxygenase / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D001161:Arteriosclerosis / Q000201:enzymology*; D019898:Autocrine Communication; D016026:Bone Marrow Transplantation; D002448:Cell Adhesion / Q000187:drug effects; D002454:Cell Differentiation / Q000187:drug effects; D002478:Cells, Cultured / Q000166:cytology / Q000187:drug effects / Q000201:enzymology; D015237:Dinoprost / Q000031:analogs & derivatives* / Q000097:blood; D042783:Endothelial Cells / Q000187:drug effects / Q000201:enzymology*; D004730:Endothelium, Vascular / Q000166:cytology; D005487:Foam Cells / Q000166:cytology*; D006938:Hyperlipoproteinemia Type II / Q000097:blood / Q000201:enzymology* / Q000235:genetics; D015847:Interleukin-4 / Q000494:pharmacology; D008077:Lipoproteins, LDL / Q000494:pharmacology; D017737:Macrophages, Peritoneal / Q000166:cytology / Q000187:drug effects / Q000201:enzymology*; D051379:Mice; D018345:Mice, Knockout; D009131:Muscle, Smooth, Vascular / Q000166:cytology; D032389:Myocytes, Smooth Muscle / Q000166:cytology / Q000187:drug effects / Q000201:enzymology*; D012333:RNA, Messenger / Q000096:biosynthesis; D011828:Radiation Chimera; D014280:Triglycerides / Q000097:blood
C475064:12-15-lipoxygenase; C115626:8,12-iso-isoprostane F2alpha-VI; D001057:Apolipoproteins E; D008077:Lipoproteins, LDL; D012333:RNA, Messenger; D014280:Triglycerides; C032629:acetyl-LDL; D015847:Interleukin-4; D015237:Dinoprost; D001092:Arachidonate 12-Lipoxygenase; D001093:Arachidonate 15-Lipoxygenase