IL-8 and its CXCR1 and CXCR2 receptors participate in the control of megakaryocytic proliferation, differentiation, and ploidy in myeloid metaplasia with myelofibrosis.
Emadi
Sharareh
S
Institut National de la Santé et de la Recherche Médicale, Unit 602, André Lwoff Institute, Paul Brousse Hospital, Villejuif, France.
Clay
Denis
D
Desterke
Christophe
C
Guerton
Bernadette
B
Maquarre
Eliane
E
Charpentier
Agnès
A
Jasmin
Claude
C
Le Bousse-Kerdilès
Marie-Caroline
MC
D000368:Aged; D000906:Antibodies / Q000494:pharmacology; D018952:Antigens, CD34 / Q000378:metabolism; D001792:Blood Platelets / Q000502:physiology; D002454:Cell Differentiation / Q000276:immunology; D002455:Cell Division / Q000276:immunology; D015870:Gene Expression / Q000276:immunology; D006801:Humans; D016209:Interleukin-8 / Q000097:blood* / Q000235:genetics; D008533:Megakaryocytes / Q000166:cytology* / Q000502:physiology; D008875:Middle Aged; D009500:Neutralization Tests; D011003:Ploidies; D055728:Primary Myelofibrosis / Q000378:metabolism / Q000503:physiopathology*; D023062:Receptors, Interleukin-8A / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D023063:Receptors, Interleukin-8B / Q000235:genetics / Q000276:immunology / Q000378:metabolism*
D000906:Antibodies; D018952:Antigens, CD34; D016209:Interleukin-8; D023062:Receptors, Interleukin-8A; D023063:Receptors, Interleukin-8B