Comparison of the antinociceptive activity of two new NO-releasing derivatives of the NSAID S-ketoprofen in rats.
Gaitan
Gema
G
Departamento de Fisiología, Facultad de Medicina, Universidad de Alcalá, Madrid, Spain.
Ahuir
F Javier
FJ
Del Soldato
Piero
P
Herrero
Juan F
JF
D000700:Analgesics; D000758:Anesthesia; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D001522:Behavior, Animal / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D002351:Carrageenan; D004305:Dose-Response Relationship, Drug; D004487:Edema / Q000139:chemically induced / Q000517:prevention & control; D004558:Electric Stimulation; D007660:Ketoprofen / Q000031:analogs & derivatives* / Q000494:pharmacology*; D008297:Male; D009046:Motor Neurons / Q000187:drug effects; D018482:Muscle, Skeletal / Q000187:drug effects / Q000294:innervation; D009569:Nitric Oxide / Q000378:metabolism*; D010147:Pain Measurement / Q000187:drug effects; D010812:Physical Stimulation; D051381:Rats; D017208:Rats, Wistar; D012018:Reflex / Q000187:drug effects
D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D009569:Nitric Oxide; D002351:Carrageenan; D007660:Ketoprofen