A novel imaging probe for in vivo detection of neuritic and diffuse amyloid plaques in the brain.
Okamura
Nobuyuki
N
BF Research Institute, c/o National Cardiovascular Center, Fujishiro-dai, Suita, Osaka, Japan. oka@mail.tains.tohoku.ac.jp
Suemoto
Takahiro
T
Shiomitsu
Tsuyoshi
T
Suzuki
Masako
M
Shimadzu
Hiroshi
H
Akatsu
Hiroyasu
H
Yamamoto
Takayuki
T
Arai
Hiroyuki
H
Sasaki
Hidetada
H
Yanai
Kazuhiko
K
Staufenbiel
Matthias
M
Kudo
Yukitsuka
Y
Sawada
Tohru
T
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000378:metabolism / Q000473:pathology; D016229:Amyloid beta-Peptides / Q000378:metabolism*; D000818:Animals; D001583:Benzoxazoles / Q000737:chemistry / Q000378:metabolism; D001921:Brain / Q000166:cytology / Q000378:metabolism / Q000473:pathology*; D003952:Diagnostic Imaging; D005260:Female; D005456:Fluorescent Dyes / Q000737:chemistry / Q000378:metabolism*; D017611:Fluorine Compounds / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D008297:Male; D051379:Mice; D008822:Mice, Transgenic; D015394:Molecular Structure; D058225:Plaque, Amyloid / Q000737:chemistry / Q000378:metabolism / Q000473:pathology; D049268:Positron-Emission Tomography / Q000379:methods*
D016229:Amyloid beta-Peptides; D001583:Benzoxazoles; D005456:Fluorescent Dyes; D017611:Fluorine Compounds