GABA(A) agonists and partial agonists: THIP (Gaboxadol) as a non-opioid analgesic and a novel type of hypnotic.
Krogsgaard-Larsen
Povl
P
Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, 2 Universitetsparken, DK-2100 Copenhagen, Denmark. ano@carlsbergfondet.dk
Frølund
Bente
B
Liljefors
Tommy
T
Ebert
Bjarke
B
D018712:Analgesics, Non-Narcotic / Q000494:pharmacology; D001007:Anxiety / Q000188:drug therapy; D018755:GABA Agonists / Q000494:pharmacology* / Q000627:therapeutic use; D018756:GABA Antagonists / Q000494:pharmacology; D058785:GABA-A Receptor Agonists; D058787:GABA-A Receptor Antagonists; D006801:Humans; D006993:Hypnotics and Sedatives / Q000494:pharmacology; D007555:Isoxazoles / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D010880:Piperidines / Q000737:chemistry / Q000494:pharmacology; D012893:Sleep Wake Disorders / Q000188:drug therapy
D018712:Analgesics, Non-Narcotic; D018755:GABA Agonists; D018756:GABA Antagonists; D058785:GABA-A Receptor Agonists; D058787:GABA-A Receptor Antagonists; D006993:Hypnotics and Sedatives; D007555:Isoxazoles; D010880:Piperidines; C073009:5-(4-piperidyl)isoxazol-3-ol; C015542:gaboxadol