Protective effects of vitamin A and vitamin E succinate against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced body wasting, hepatomegaly, thymic atrophy, production of reactive oxygen species and DNA damage in C57BL/6J mice.
Alsharif
Naser Z
NZ
Creighton University Medical Center, School of Pharmacy & Health Professions, Department of Pharmacy Sciences, Omaha, NE 68178, USA. nalshari@creighton.edu
Hassoun
Ezdihar A
EA
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001284:Atrophy / Q000139:chemically induced / Q000517:prevention & control; D004249:DNA Damage / Q000187:drug effects; D005260:Female; D006529:Hepatomegaly / Q000139:chemically induced / Q000517:prevention & control; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D051379:Mice; D008810:Mice, Inbred C57BL; D009929:Organ Size / Q000187:drug effects; D018384:Oxidative Stress / Q000187:drug effects*; D010533:Peritoneal Lavage; D000072317:Polychlorinated Dibenzodioxins / Q000037:antagonists & inhibitors* / Q000633:toxicity; D017382:Reactive Oxygen Species / Q000378:metabolism; D013950:Thymus Gland / Q000187:drug effects* / Q000473:pathology; D024505:Tocopherols; D014801:Vitamin A / Q000494:pharmacology*; D014810:Vitamin E / Q000031:analogs & derivatives* / Q000494:pharmacology*; D015431:Weight Loss / Q000187:drug effects; D015262:Xenobiotics / Q000037:antagonists & inhibitors* / Q000633:toxicity
D000975:Antioxidants; D000072317:Polychlorinated Dibenzodioxins; D017382:Reactive Oxygen Species; D015262:Xenobiotics; D014801:Vitamin A; D014810:Vitamin E; D024505:Tocopherols