A cyclic peptide, L1AD3, induces early signs of apoptosis in human leukemic T-cell lines.
Smith
Charles A
CA
Department of Medicinal and Biological Chemistry, College of Pharmacy, The University of Toledo, Toledo, OH 43606, USA. charlesasmithphd@buckeye-express.com
Hinman
Channing L
CL
D000595:Amino Acid Sequence; D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects* / Q000502:physiology; D020169:Caspases / Q000187:drug effects; D002460:Cell Line; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D002942:Circular Dichroism; D004179:Cobra Cardiotoxin Proteins / Q000138:chemical synthesis / Q000494:pharmacology*; D006801:Humans; D007938:Leukemia / Q000473:pathology*; D007962:Leukocytes / Q000187:drug effects; D008958:Models, Molecular; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D051381:Rats; D013329:Structure-Activity Relationship; D013601:T-Lymphocytes / Q000187:drug effects*
D000970:Antineoplastic Agents; D004179:Cobra Cardiotoxin Proteins; C494064:L1AD3 peptide, Naja naja atra; D020169:Caspases