Structural and functional characterization of "laboratory evolved" cytochrome P450cam mutants showing enhanced naphthalene oxygenation activity.
Matsuura
Koji
K
Department of Molecular Engineering, Graduate School of Engineering, Kyoto University, Nishikyo, Kyoto 615-8510, Japan.
Tosha
Takehiko
T
Yoshioka
Shiro
S
Takahashi
Satoshi
S
Ishimori
Koichiro
K
Morishima
Isao
I
D019943:Amino Acid Substitution; D019475:Camphor 5-Monooxygenase / Q000737:chemistry*; D004789:Enzyme Activation; D004795:Enzyme Stability; D016297:Mutagenesis, Site-Directed; D009154:Mutation; D009281:Naphthalenes / Q000737:chemistry*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D011487:Protein Conformation; D021281:Quantitative Structure-Activity Relationship; D011994:Recombinant Proteins / Q000737:chemistry
D009281:Naphthalenes; D011994:Recombinant Proteins; C031721:naphthalene; D019475:Camphor 5-Monooxygenase; D010100:Oxygen