Microbial oxidation of terfenadine and ebastine into fexofenadine and carebastine.
Mazier
Claire
C
Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, URA 400 CNRS, Université René Descartes Paris V, 45 rue des Saints-Pères, 75270 Paris Cedex 06, France.
Jaouen
Maryse
M
Sari
Marie-Agnès
MA
Buisson
Didier
D
D020095:Absidia / Q000378:metabolism*; D001711:Biotransformation; D002090:Butyrophenones / Q000378:metabolism*; D020093:Cunninghamella / Q000378:metabolism*; D006634:Histamine H1 Antagonists / Q000378:metabolism; D010084:Oxidation-Reduction; D010880:Piperidines / Q000378:metabolism*; D013305:Streptomyces griseus / Q000378:metabolism*; D016593:Terfenadine / Q000031:analogs & derivatives* / Q000378:metabolism*
D002090:Butyrophenones; D006634:Histamine H1 Antagonists; D010880:Piperidines; C058251:carebastine; D016593:Terfenadine; C093230:fexofenadine; C058249:ebastine