Abl tyrosine kinase promotes dendrogenesis by inducing actin cytoskeletal rearrangements in cooperation with Rho family small GTPases in hippocampal neurons.
Jones
Shiloh B
SB
Department of Anatomy and Cell Biology, The Brody School of Medicine at East Carolina University, Greenville, North Carolina 27858, USA.
Lu
Hope Y
HY
Lu
Qun
Q
D008841:Actin Cytoskeleton / Q000187:drug effects; D000199:Actins / Q000378:metabolism*; D000577:Amides / Q000494:pharmacology; D000818:Animals; D001369:Axons / Q000187:drug effects / Q000502:physiology; D001549:Benzamides; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000494:pharmacology; D002478:Cells, Cultured; D003599:Cytoskeleton / Q000187:drug effects / Q000648:ultrastructure*; D003712:Dendrites / Q000187:drug effects / Q000502:physiology*; D006624:Hippocampus / Q000166:cytology / Q000196:embryology / Q000201:enzymology* / Q000648:ultrastructure; D000068877:Imatinib Mesylate; D008869:Microtubule-Associated Proteins / Q000378:metabolism; D009474:Neurons / Q000187:drug effects / Q000201:enzymology / Q000648:ultrastructure; D010879:Piperazines / Q000494:pharmacology; D016315:Proto-Oncogene Proteins c-abl / Q000037:antagonists & inhibitors / Q000502:physiology*; D011725:Pyridines / Q000494:pharmacology; D011743:Pyrimidines / Q000494:pharmacology; D051381:Rats; D015398:Signal Transduction / Q000502:physiology; D013844:Thiazoles / Q000494:pharmacology; D053778:Thiazolidines; D020764:cdc42 GTP-Binding Protein / Q000378:metabolism; D020830:rac1 GTP-Binding Protein / Q000378:metabolism; D020741:rho GTP-Binding Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000502:physiology*
D000199:Actins; D000577:Amides; D001549:Benzamides; D019086:Bridged Bicyclo Compounds, Heterocyclic; D008869:Microtubule-Associated Proteins; D010879:Piperazines; D011725:Pyridines; D011743:Pyrimidines; D013844:Thiazoles; D053778:Thiazolidines; C108830:Y 27632; D000068877:Imatinib Mesylate; D016315:Proto-Oncogene Proteins c-abl; D020764:cdc42 GTP-Binding Protein; D020830:rac1 GTP-Binding Protein; D020741:rho GTP-Binding Proteins; C037067:latrunculin A