title: Identification of the rabbit liver UDP-glucuronosyltransferase catalyzing the glucuronidation of 4-ethoxyphenylurea (dulcin).
authors.affiliation: Clinical Pharmaceutics Laboratory, Department of Pharmaceutics, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan. uesawa@my-pharm.ac.jp
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Uesawa
authors.forename: Adam G
authors.initials: AG
authors.lastname: Staines
authors.forename: Audrey
authors.initials: A
authors.lastname: O'Sullivan
authors.forename: Kiminori
authors.initials: K
authors.lastname: Mohri
authors.forename: Brian
authors.initials: B
authors.lastname: Burchell
mesh_terms: D000818:Animals; D015153:Blotting, Western; D019556:COS Cells; D002522:Chlorocebus aethiops; D002851:Chromatography, High Pressure Liquid; D002853:Chromatography, Liquid; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005707:Gallic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology; D020719:Glucuronides / Q000378:metabolism*; D014453:Glucuronosyltransferase / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D066298:In Vitro Techniques; D007527:Isoenzymes; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism; D010671:Phenylurea Compounds / Q000493:pharmacokinetics*; D011506:Proteins / Q000378:metabolism; D011817:Rabbits; D021241:Spectrometry, Mass, Electrospray Ionization; D014162:Transfection
chemical_list: D004791:Enzyme Inhibitors; D020719:Glucuronides; D007527:Isoenzymes; D010671:Phenylurea Compounds; D011506:Proteins; C016627:octyl gallate; D005707:Gallic Acid; C004352:dulcin; D014453:Glucuronosyltransferase; C107611:UDP-glucuronosyltransferase, UGT1A7