title: Induction of cyclooxygenase-2 overexpression in human gastric epithelial cells by Helicobacter pylori involves TLR2/TLR9 and c-Src-dependent nuclear factor-kappaB activation.
authors.affiliation: Department of Pharmacology, College of Medicine, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Ya Jen
authors.initials: YJ
authors.lastname: Chang
authors.forename: Ming Shiang
authors.initials: MS
authors.lastname: Wu
authors.forename: Jaw Town
authors.initials: JT
authors.lastname: Lin
authors.forename: Bor Shyang
authors.initials: BS
authors.lastname: Sheu
authors.forename: Tatsushi
authors.initials: T
authors.lastname: Muta
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Inoue
authors.forename: Ching-Chow
authors.initials: CC
authors.lastname: Chen
mesh_terms: D022762:CCAAT-Enhancer-Binding Proteins / Q000378:metabolism; D017362:Cyclic AMP Response Element-Binding Protein / Q000378:metabolism; D051546:Cyclooxygenase 2; D004789:Enzyme Activation; D005753:Gastric Mucosa / Q000201:enzymology* / Q000382:microbiology; D015971:Gene Expression Regulation, Enzymologic; D016391:Genes, src / Q000502:physiology*; D016480:Helicobacter pylori / Q000502:physiology*; D006801:Humans; D007700:Kinetics; D008562:Membrane Glycoproteins / Q000502:physiology*; D008565:Membrane Proteins; D008745:Methylation; D016328:NF-kappa B / Q000378:metabolism*; D011401:Promoter Regions, Genetic; D011451:Prostaglandin-Endoperoxide Synthases / Q000096:biosynthesis / Q000235:genetics*; D011956:Receptors, Cell Surface / Q000502:physiology*; D051195:Toll-Like Receptor 2; D051197:Toll-Like Receptor 4; D051217:Toll-Like Receptor 9; D051193:Toll-Like Receptors
chemical_list: D022762:CCAAT-Enhancer-Binding Proteins; D017362:Cyclic AMP Response Element-Binding Protein; D008562:Membrane Glycoproteins; D008565:Membrane Proteins; D016328:NF-kappa B; D011956:Receptors, Cell Surface; C495342:TLR2 protein, human; C495345:TLR4 protein, human; C495371:TLR9 protein, human; D051195:Toll-Like Receptor 2; D051197:Toll-Like Receptor 4; D051217:Toll-Like Receptor 9; D051193:Toll-Like Receptors; D051546:Cyclooxygenase 2; C496540:PTGS2 protein, human; D011451:Prostaglandin-Endoperoxide Synthases