Construction, training and clinical validation of an interpretation system for genotypic HIV-1 drug resistance based on fuzzy rules revised by virological outcomes.
De Luca
Andrea
A
Institute of Clinical Infectious Diseases, Catholic University, Rome, Italy. andrea.deluca@rm.unicatt.it
Vendittelli
Marilena
M
Baldini
Francesco
F
Di Giambenedetto
Simona
S
Trotta
Maria Paola
MP
Cingolani
Antonella
A
Bacarelli
Alessandra
A
Gori
Caterina
C
Perno
Carlo Federico
CF
Antinori
Andrea
A
Ulivi
Giovanni
G
D000293:Adolescent; D000328:Adult; D000368:Aged; D000465:Algorithms; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active; D002986:Clinical Trials as Topic; D030541:Databases, Genetic; D024882:Drug Resistance, Viral / Q000235:genetics*; D004359:Drug Therapy, Combination; D005260:Female; D017143:Fuzzy Logic; D005838:Genotype; D015658:HIV Infections / Q000188:drug therapy* / Q000821:virology; D016333:HIV Protease / Q000235:genetics; D054303:HIV Reverse Transcriptase / Q000235:genetics; D015497:HIV-1 / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D009154:Mutation; D015203:Reproducibility of Results; D016879:Salvage Therapy
D044966:Anti-Retroviral Agents; D054303:HIV Reverse Transcriptase; D016333:HIV Protease