title: A new HOPE for aldosterone blockade?
authors.forename: Bertram
authors.initials: B
authors.lastname: Pitt
mesh_terms: D000450:Aldosterone / Q000096:biosynthesis / Q000502:physiology*; D000804:Angiotensin II / Q000502:physiology; D047228:Angiotensin II Type 1 Receptor Blockers / Q000494:pharmacology / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D000808:Angiotensinogen / Q000235:genetics; D000818:Animals; D003327:Coronary Disease / Q000188:drug therapy / Q000503:physiopathology* / Q000517:prevention & control; D019405:Cytochrome P-450 CYP11B2 / Q000096:biosynthesis / Q000235:genetics; D004359:Drug Therapy, Combination; D004730:Endothelium, Vascular / Q000187:drug effects / Q000378:metabolism; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D008077:Lipoproteins, LDL / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D000451:Mineralocorticoid Receptor Antagonists / Q000494:pharmacology / Q000627:therapeutic use*; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000378:metabolism; D032383:Myocytes, Cardiac / Q000187:drug effects / Q000378:metabolism; D009569:Nitric Oxide / Q000378:metabolism; D051381:Rats; D044140:Receptor, Angiotensin, Type 1 / Q000502:physiology; D011973:Receptors, LDL / Q000502:physiology; D018161:Receptors, Mineralocorticoid / Q000187:drug effects / Q000502:physiology; D051131:Receptors, Oxidized LDL; D011993:Recombinant Fusion Proteins / Q000502:physiology; D012083:Renin / Q000235:genetics; D051127:Scavenger Receptors, Class E; D015398:Signal Transduction
chemical_list: D047228:Angiotensin II Type 1 Receptor Blockers; D000806:Angiotensin-Converting Enzyme Inhibitors; D008077:Lipoproteins, LDL; D000451:Mineralocorticoid Receptor Antagonists; C495137:OLR1 protein, human; C495136:OLR1 protein, rat; C495138:Olr1 protein, mouse; D044140:Receptor, Angiotensin, Type 1; D011973:Receptors, LDL; D018161:Receptors, Mineralocorticoid; D051131:Receptors, Oxidized LDL; D011993:Recombinant Fusion Proteins; D051127:Scavenger Receptors, Class E; C099252:oxidized low density lipoprotein; D000808:Angiotensinogen; D000804:Angiotensin II; D009569:Nitric Oxide; D000450:Aldosterone; D019405:Cytochrome P-450 CYP11B2; D012083:Renin