Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors.
Möllemann
Maria
M
Department of Neuropathology, Heinrich-Heine-University, Düsseldorf, Germany.
Wolter
Marietta
M
Felsberg
Jörg
J
Collins
V Peter
VP
Reifenberger
Guido
G
D000293:Adolescent; D000328:Adult; D000368:Aged; D001254:Astrocytoma / Q000235:genetics*; D001932:Brain Neoplasms / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D002878:Chromosomes, Human, Pair 1 / Q000235:genetics; D002888:Chromosomes, Human, Pair 19 / Q000235:genetics; D018899:CpG Islands; D019175:DNA Methylation; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D019656:Loss of Heterozygosity; D008297:Male; D008875:Middle Aged; D019853:O(6)-Methylguanine-DNA Methyltransferase / Q000235:genetics*; D009837:Oligodendroglioma / Q000235:genetics*; D011401:Promoter Regions, Genetic / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction
D012333:RNA, Messenger; D019853:O(6)-Methylguanine-DNA Methyltransferase