Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit.
Ogris
Waltraud
W
Division of Biochemistry and Molecular Biology, Brain Research Institute, Medical University of Vienna, Spitalgasse 4, A-1090 Vienna, Austria.
Pöltl
Angelika
A
Hauer
Birgit
B
Ernst
Margot
M
Oberto
Alessandra
A
Wulff
Peer
P
Höger
Harald
H
Wisden
William
W
Sieghart
Werner
W
D000818:Animals; D001569:Benzodiazepines / Q000494:pharmacology*; D001665:Binding Sites; D000078306:Clobazam; D005260:Female; D005445:Flunitrazepam / Q000494:pharmacology; D008024:Ligands; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008958:Models, Molecular; D017354:Point Mutation; D011487:Protein Conformation; D021122:Protein Subunits / Q000737:chemistry / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*; D011963:Receptors, GABA-A / Q000737:chemistry / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*
D008024:Ligands; D021122:Protein Subunits; D011963:Receptors, GABA-A; D001569:Benzodiazepines; D000078306:Clobazam; D005445:Flunitrazepam