Identification of a novel co-regulator interaction surface on the ligand binding domain of Nurr1 using NMR footprinting.
Codina
Anna
A
Medical Research Council-Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK.
Benoit
Gerard
G
Gooch
John T
JT
Neuhaus
David
D
Perlmann
Thomas
T
Schwabe
John W R
JW
D000595:Amino Acid Sequence; D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism; D002474:Cell-Free System; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000502:physiology*; D004330:Drosophila; D006801:Humans; D007700:Kinetics; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D051379:Mice; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009154:Mutation; D009474:Neurons / Q000378:metabolism; D057126:Nuclear Receptor Subfamily 4, Group A, Member 2; D010455:Peptides / Q000737:chemistry; D011485:Protein Binding; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D011994:Recombinant Proteins / Q000737:chemistry; D017386:Sequence Homology, Amino Acid; D013050:Spectrometry, Fluorescence; D013388:Succinimides / Q000737:chemistry; D014157:Transcription Factors / Q000737:chemistry / Q000502:physiology*; D014364:Tryptophan / Q000737:chemistry
D004268:DNA-Binding Proteins; D008024:Ligands; C539882:NR4A2 protein, human; C539883:Nr4a2 protein, mouse; D057126:Nuclear Receptor Subfamily 4, Group A, Member 2; D010455:Peptides; D011994:Recombinant Proteins; D013388:Succinimides; D014157:Transcription Factors; D014364:Tryptophan; C001426:N-hydroxysuccinimide