title: Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option.
authors.affiliation: Department of Pathology, University Medical Centre St. Radboud, Nijmegen, the Netherlands. w.leenders@pathol.umcn.nl
authors.forename: William P J
authors.initials: WP
authors.lastname: Leenders
authors.forename: Benno
authors.initials: B
authors.lastname: Küsters
authors.forename: Kiek
authors.initials: K
authors.lastname: Verrijp
authors.forename: Cathy
authors.initials: C
authors.lastname: Maass
authors.forename: Pieter
authors.initials: P
authors.lastname: Wesseling
authors.forename: Arend
authors.initials: A
authors.lastname: Heerschap
authors.forename: Dirk
authors.initials: D
authors.lastname: Ruiter
authors.forename: Andy
authors.initials: A
authors.lastname: Ryan
authors.forename: Robert
authors.initials: R
authors.lastname: de Waal
mesh_terms: D020533:Angiogenesis Inhibitors / Q000494:pharmacology*; D000818:Animals; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D045744:Cell Line, Tumor; D018450:Disease Progression; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D008545:Melanoma / Q000188:drug therapy* / Q000473:pathology*; D051379:Mice; D008807:Mice, Inbred BALB C; D009336:Necrosis; D009362:Neoplasm Metastasis; D009389:Neovascularization, Pathologic; D016376:Oligonucleotides, Antisense / Q000737:chemistry; D010641:Phenotype; D010880:Piperidines / Q000494:pharmacology; D010919:Placebos; D011799:Quinazolines / Q000494:pharmacology; D012313:RNA / Q000378:metabolism; D014162:Transfection; D016896:Treatment Outcome; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism
chemical_list: D020533:Angiogenesis Inhibitors; D016376:Oligonucleotides, Antisense; D010880:Piperidines; D010919:Placebos; D011799:Quinazolines; D042461:Vascular Endothelial Growth Factor A; D012313:RNA; C452423:vandetanib