Selective enhancement of tonic GABAergic inhibition in murine hippocampal neurons by low concentrations of the volatile anesthetic isoflurane.
Caraiscos
Valerie B
VB
Institute of Medical Science, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Newell
J Glen
JG
You-Ten
Kong E
KE
Elliott
Erin M
EM
Rosahl
Thomas W
TW
Wafford
Keith A
KA
MacDonald
John F
JF
Orser
Beverley A
BA
D018685:Anesthetics, Inhalation / Q000494:pharmacology*; D000818:Animals; D002478:Cells, Cultured; D002540:Cerebral Cortex / Q000166:cytology; D004305:Dose-Response Relationship, Drug; D005071:Evoked Potentials / Q000187:drug effects; D019706:Excitatory Postsynaptic Potentials / Q000187:drug effects; D006624:Hippocampus / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D007530:Isoflurane / Q000494:pharmacology*; D051379:Mice; D018345:Mice, Knockout; D009433:Neural Inhibition / Q000187:drug effects*; D017966:Pyramidal Cells / Q000187:drug effects / Q000502:physiology; D011963:Receptors, GABA-A / Q000187:drug effects* / Q000235:genetics / Q000502:physiology; D011994:Recombinant Proteins; D009435:Synaptic Transmission / Q000187:drug effects*
D018685:Anesthetics, Inhalation; C496250:Gabra5 protein, mouse; D011963:Receptors, GABA-A; D011994:Recombinant Proteins; D007530:Isoflurane