Mutations in the DNA-binding domain of the transcription factor Bright act as dominant negative proteins and interfere with immunoglobulin transactivation.
Nixon
Jamee C
JC
Oklahoma Medical Research Foundation, 825 N. E. 13 Street, Oklahoma City, Oklahoma 73104, USA.
Rajaiya
Jaya
J
Webb
Carol F
CF
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D001665:Binding Sites / Q000235:genetics; D016466:CHO Cells; D002460:Cell Line; D006224:Cricetinae; D004247:DNA / Q000235:genetics / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D019281:Dimerization; D007148:Immunoglobulin mu-Chains / Q000235:genetics*; D066298:In Vitro Techniques; D051379:Mice; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D009857:Oncogenes / Q000235:genetics*; D020836:Protein Structure, Quaternary; D017434:Protein Structure, Tertiary; D011994:Recombinant Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D015534:Trans-Activators / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D014157:Transcription Factors; D015533:Transcriptional Activation; D014162:Transfection
C097532:Arid3a protein, mouse; D004268:DNA-Binding Proteins; D007148:Immunoglobulin mu-Chains; D011994:Recombinant Proteins; D015534:Trans-Activators; D014157:Transcription Factors; D004247:DNA