title: Synthesis and evaluation of the affinity toward mu-opioid receptors of atypical, lipophilic ligands based on the sequence c[-Tyr-Pro-Trp-Phe-Gly-].
authors.affiliation: Dipartimento di Chimica G. Ciamician and CSFM, via Selmi 2, Università di Bologna, 40126 Bologna, Italy. giuliana.cardillo@unibo.it
authors.forename: Giuliana
authors.initials: G
authors.lastname: Cardillo
authors.forename: Luca
authors.initials: L
authors.lastname: Gentilucci
authors.forename: Alessandra
authors.initials: A
authors.lastname: Tolomelli
authors.forename: Raffaella
authors.initials: R
authors.lastname: Spinosa
authors.forename: Maria
authors.initials: M
authors.lastname: Calienni
authors.forename: Ahmed R
authors.initials: AR
authors.lastname: Qasem
authors.forename: Santi
authors.initials: S
authors.lastname: Spampinato
mesh_terms: D000818:Animals; D001667:Binding, Competitive; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D000242:Cyclic AMP / Q000096:biosynthesis; D066298:In Vitro Techniques; D008024:Ligands; D010456:Peptides, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011869:Radioligand Assay; D051381:Rats; D017450:Receptors, Opioid, mu / Q000819:agonists* / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D008024:Ligands; D010456:Peptides, Cyclic; D017450:Receptors, Opioid, mu; C492968:cyclo(tyrosyl-prolyl-tryptophyl-phenylalanyl-glycyl); D000242:Cyclic AMP