title: Genetically determined resistance to collagenase action augments interstitial collagen accumulation in atherosclerotic plaques.
authors.affiliation: Donald W. Reynolds Cardiovascular Clinical Research Center, Department of Medicine, and Women's Hospital, Harvard Medical School, Boston, Mass 02115, USA.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Fukumoto
authors.forename: Jun-o
authors.initials: JO
authors.lastname: Deguchi
authors.forename: Peter
authors.initials: P
authors.lastname: Libby
authors.forename: Elena
authors.initials: E
authors.lastname: Rabkin-Aikawa
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Sakata
authors.forename: Michael T
authors.initials: MT
authors.lastname: Chin
authors.forename: Christopher C
authors.initials: CC
authors.lastname: Hill
authors.forename: Patrick R
authors.initials: PR
authors.lastname: Lawler
authors.forename: Nerea
authors.initials: N
authors.lastname: Varo
authors.forename: Frederick J
authors.initials: FJ
authors.lastname: Schoen
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Krane
authors.forename: Masanori
authors.initials: M
authors.lastname: Aikawa
mesh_terms: D019943:Amino Acid Substitution; D000818:Animals; D001057:Apolipoproteins E / Q000172:deficiency / Q000235:genetics; D002452:Cell Count; D016923:Cell Death; D002465:Cell Movement; D024042:Collagen Type I / Q000235:genetics / Q000378:metabolism*; D017364:Collagenases / Q000378:metabolism*; D003324:Coronary Artery Disease / Q000201:enzymology* / Q000235:genetics / Q000473:pathology; D003433:Crosses, Genetic; D004036:Diet, Atherogenic; D008264:Macrophages / Q000201:enzymology*; D017737:Macrophages, Peritoneal / Q000201:enzymology; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D009131:Muscle, Smooth, Vascular / Q000473:pathology; D013379:Substrate Specificity / Q000235:genetics; D017539:Tunica Intima / Q000473:pathology
chemical_list: D001057:Apolipoproteins E; D024042:Collagen Type I; D017364:Collagenases