Para-Bromophenacyl bromide alleviates airway hyperresponsiveness and modulates cytokines, IgE and eosinophil levels in ovalbumin-sensitized and -challenged mice.
Ram
Arjun
A
Molecular Immunology and Immunogenetics Laboratory, Institute of Genomics and Integrative Biology, Mall Road, Delhi-110007, India.
Das
Moumita
M
Gangal
Sharad V
SV
Ghosh
Balaram
B
D000098:Acetophenones / Q000009:adverse effects / Q000276:immunology / Q000627:therapeutic use*; D000280:Administration, Inhalation; D000336:Aerosols; D000402:Airway Obstruction / Q000139:chemically induced / Q000276:immunology / Q000517:prevention & control; D000818:Animals; D016535:Bronchial Hyperreactivity / Q000139:chemically induced / Q000276:immunology / Q000517:prevention & control*; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology / Q000276:immunology; D002452:Cell Count; D016207:Cytokines / Q000145:classification / Q000187:drug effects* / Q000276:immunology; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004804:Eosinophils / Q000187:drug effects* / Q000276:immunology; D007114:Immunization / Q000379:methods*; D007073:Immunoglobulin E / Q000097:blood / Q000187:drug effects* / Q000276:immunology; D007194:India; D008297:Male; D016210:Methacholine Chloride / Q000009:adverse effects / Q000037:antagonists & inhibitors; D051379:Mice; D008807:Mice, Inbred BALB C; D010047:Ovalbumin / Q000009:adverse effects / Q000276:immunology*; D010741:Phospholipases A / Q000037:antagonists & inhibitors / Q000627:therapeutic use
D000098:Acetophenones; D000336:Aerosols; D016207:Cytokines; D016210:Methacholine Chloride; D007073:Immunoglobulin E; D010047:Ovalbumin; D010741:Phospholipases A; C006821:4-bromophenacyl bromide