Heat-induced oligomerization of gp96 occurs via a site distinct from substrate binding and is regulated by ATP.
Thorne
Meghan E
ME
Department of Chemistry and Biochemistry, Bradley University, 1501 West Bradley Avenue, Peoria, IL 61625, USA.
McQuade
Kristi L
KL
D000255:Adenosine Triphosphate / Q000737:chemistry*; D001665:Binding Sites / Q000528:radiation effects; D019281:Dimerization; D004789:Enzyme Activation; D004795:Enzyme Stability; D018840:HSP70 Heat-Shock Proteins / Q000737:chemistry* / Q000528:radiation effects*; D006358:Hot Temperature; D007700:Kinetics; D008565:Membrane Proteins / Q000737:chemistry* / Q000528:radiation effects*; D008970:Molecular Weight; D011485:Protein Binding / Q000528:radiation effects; D013329:Structure-Activity Relationship
D018840:HSP70 Heat-Shock Proteins; D008565:Membrane Proteins; C018551:glucose-regulated proteins; D000255:Adenosine Triphosphate