Pig muscle carnitine palmitoyltransferase I (CPTI beta), with low Km for carnitine and low sensitivity to malonyl-CoA inhibition, has kinetic characteristics similar to those of the rat liver (CPTI alpha) enzyme.
Relat
Joana
J
Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, 08028 Barcelona, Spain.
Nicot
Carine
C
Gacias
Mar
M
Woldegiorgis
Gebre
G
Marrero
Pedro F
PF
Haro
Diego
D
D000595:Amino Acid Sequence; D000818:Animals; D002331:Carnitine / Q000737:chemistry*; D002334:Carnitine O-Palmitoyltransferase / Q000037:antagonists & inhibitors* / Q000096:biosynthesis / Q000737:chemistry* / Q000235:genetics; D003001:Cloning, Molecular; D004791:Enzyme Inhibitors / Q000737:chemistry*; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000737:chemistry / Q000235:genetics; D007700:Kinetics; D008316:Malonyl Coenzyme A / Q000737:chemistry*; D051379:Mice; D008930:Mitochondria, Liver / Q000201:enzymology*; D008931:Mitochondria, Muscle / Q000201:enzymology*; D008969:Molecular Sequence Data; D051381:Rats; D011994:Recombinant Proteins / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000737:chemistry; D017386:Sequence Homology, Amino Acid; D013552:Swine
D004791:Enzyme Inhibitors; D007527:Isoenzymes; D011994:Recombinant Proteins; D008316:Malonyl Coenzyme A; D002334:Carnitine O-Palmitoyltransferase; D002331:Carnitine