title: Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming.
authors.affiliation: Laboratory of Developmental Genetics and Imprinting, Developmental Genetics Programme, The Babraham Institute, Cambridge CB2 4AT, United Kingdom.
authors.forename: Hugh D
authors.initials: HD
authors.lastname: Morgan
authors.forename: Wendy
authors.initials: W
authors.lastname: Dean
authors.forename: Heather A
authors.initials: HA
authors.lastname: Coker
authors.forename: Wolf
authors.initials: W
authors.lastname: Reik
authors.forename: Svend K
authors.initials: SK
authors.lastname: Petersen-Mahrt
mesh_terms: D000071479:APOBEC-1 Deaminase; D000619:Aminohydrolases / Q000235:genetics / Q000378:metabolism; D000818:Animals; D001483:Base Sequence; D003562:Cytidine / Q000031:analogs & derivatives* / Q000378:metabolism*; D003564:Cytidine Deaminase / Q000235:genetics / Q000378:metabolism*; D004247:DNA / Q000235:genetics / Q000378:metabolism; D019175:DNA Methylation; D044127:Epigenesis, Genetic; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism; D005260:Female; D015870:Gene Expression; D006801:Humans; D066298:In Vitro Techniques; D009154:Mutation; D051381:Rats; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism; D014018:Tissue Distribution; D000098830:AICDA (Activation-Induced Cytidine Deaminase)
chemical_list: D011994:Recombinant Proteins; D003562:Cytidine; D004247:DNA; C457060:5-methyldeoxycytidine monophosphate deaminase; D000098830:AICDA (Activation-Induced Cytidine Deaminase); D000619:Aminohydrolases; D000071479:APOBEC-1 Deaminase; C000605089:APOBEC1 protein, human; C000605091:Apobec1 protein, rat; D003564:Cytidine Deaminase; C016568:5-methylcytidine