title: Effects of altering the electronics of 2-methoxyestradiol on cell proliferation, on cytotoxicity in human cancer cell cultures, and on tubulin polymerization.
authors.affiliation: Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: Allison B
authors.initials: AB
authors.lastname: Edsall
authors.forename: Arasambattu K
authors.initials: AK
authors.lastname: Mohanakrishnan
authors.forename: Donglai
authors.initials: D
authors.lastname: Yang
authors.forename: Philip E
authors.initials: PE
authors.lastname: Fanwick
authors.forename: Ernest
authors.initials: E
authors.lastname: Hamel
authors.forename: Arthur D
authors.initials: AD
authors.lastname: Hanson
authors.forename: Gregory E
authors.initials: GE
authors.lastname: Agoston
authors.forename: Mark
authors.initials: M
authors.lastname: Cushman
mesh_terms: D000077584:2-Methoxyestradiol; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001704:Biopolymers; D002455:Cell Division / Q000187:drug effects; D045744:Cell Line, Tumor; D018360:Crystallography, X-Ray; D004354:Drug Screening Assays, Antitumor; D004958:Estradiol / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D008958:Models, Molecular; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D014404:Tubulin / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D001704:Biopolymers; D014404:Tubulin; D004958:Estradiol; D000077584:2-Methoxyestradiol