Hypoxia modulates adenosine receptors in human endothelial and smooth muscle cells toward an A2B angiogenic phenotype.
Feoktistov
Igor
I
Division of Cardiovascular Medicine, Vanderbilt University, Nashville, TN 37232-6300, USA. igor.feoktistov@vanderbilt.edu
Ryzhov
Sergey
S
Zhong
Hongyan
H
Goldstein
Anna E
AE
Matafonov
Anton
A
Zeng
Dewan
D
Biaggioni
Italo
I
D015687:Cell Hypoxia / Q000502:physiology*; D002478:Cells, Cultured; D004268:DNA-Binding Proteins / Q000502:physiology; D015536:Down-Regulation; D042783:Endothelial Cells / Q000378:metabolism*; D015870:Gene Expression; D006801:Humans; D051793:Hypoxia-Inducible Factor 1; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D032389:Myocytes, Smooth Muscle / Q000378:metabolism*; D018919:Neovascularization, Physiologic; D009687:Nuclear Proteins / Q000502:physiology; D010641:Phenotype; D012333:RNA, Messenger; D043704:Receptor, Adenosine A2B / Q000502:physiology; D018047:Receptors, Purinergic P1 / Q000502:physiology*; D014157:Transcription Factors / Q000502:physiology; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism*
D004268:DNA-Binding Proteins; C497442:HIF1A protein, human; D051793:Hypoxia-Inducible Factor 1; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D009687:Nuclear Proteins; D012333:RNA, Messenger; D043704:Receptor, Adenosine A2B; D018047:Receptors, Purinergic P1; D014157:Transcription Factors; D042461:Vascular Endothelial Growth Factor A