5-Fluorouracil-induced coronary spasm: may inhibition of hyperpolarization factors produced by CYP2C enzymes be the cause?
Karadag
Omer
O
Babaoglu
Melih Onder
MO
Altundag
Kadri
K
Elkiran
Tamer
T
Yasar
Umit
U
Bozkurt
Atila
A
D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000009:adverse effects*; D001189:Aryl Hydrocarbon Hydroxylases / Q000378:metabolism*; D003329:Coronary Vasospasm / Q000139:chemically induced* / Q000201:enzymology* / Q000378:metabolism; D065729:Cytochrome P-450 CYP2C9; D005472:Fluorouracil / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans
D000964:Antimetabolites, Antineoplastic; C450260:CYP2C9 protein, human; D065729:Cytochrome P-450 CYP2C9; D001189:Aryl Hydrocarbon Hydroxylases; D005472:Fluorouracil