Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells.
Kuo
Pao-Chen
PC
Molecular Toxicology Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, No. 7 Section 3 Chung-Yang Road, Hualien 970, Taiwan.
Liu
Huei-Fang
HF
Chao
Jui-I
JI
D017209:Apoptosis; D052160:Benzothiazoles; D015153:Blotting, Western; D002277:Carcinoma / Q000473:pathology*; D002453:Cell Cycle; D018797:Cell Cycle Proteins / Q000378:metabolism*; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D019926:Cyclin B / Q000378:metabolism; D056744:Cyclin B1; D050759:Cyclin-Dependent Kinase Inhibitor p21; D004247:DNA / Q000737:chemistry; D019084:Fluorescent Antibody Technique, Indirect; D016195:G2 Phase; D006801:Humans; D051034:Inhibitor of Apoptosis Proteins; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008858:Microscopy, Phase-Contrast; D008869:Microtubule-Associated Proteins / Q000502:physiology*; D008875:Middle Aged; D008938:Mitosis; D008954:Models, Biological; D009363:Neoplasm Proteins; D016376:Oligonucleotides, Antisense / Q000737:chemistry / Q000494:pharmacology; D010766:Phosphorylation; D021381:Protein Transport; D011794:Quercetin / Q000494:pharmacology*; D034741:RNA, Small Interfering / Q000378:metabolism; D000077022:Survivin; D013844:Thiazoles / Q000378:metabolism; D013912:Threonine / Q000378:metabolism; D013997:Time Factors; D014050:Toluene / Q000031:analogs & derivatives* / Q000378:metabolism; D014162:Transfection; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism*
C107489:BIRC5 protein, human; D052160:Benzothiazoles; C534699:CCNB1 protein, human; C493956:CDKN1A protein, human; D018797:Cell Cycle Proteins; D019926:Cyclin B; D056744:Cyclin B1; D050759:Cyclin-Dependent Kinase Inhibitor p21; D051034:Inhibitor of Apoptosis Proteins; D008869:Microtubule-Associated Proteins; D009363:Neoplasm Proteins; D016376:Oligonucleotides, Antisense; D034741:RNA, Small Interfering; D000077022:Survivin; D013844:Thiazoles; D016159:Tumor Suppressor Protein p53; D013912:Threonine; D014050:Toluene; D004247:DNA; D011794:Quercetin; C121565:pifithrin