Evidence for the involvement of nitric oxide in 3,4-methylenedioxymethamphetamine-induced serotonin depletion in the rat brain.
Darvesh
Altaf S
AS
University of Cincinnati, College of Pharmacy, 3223 Eden Ave., Cincinnati, OH 45267, USA.
Yamamoto
Bryan K
BK
Gudelsky
Gary A
GA
D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects*; D002956:Citrulline / Q000031:analogs & derivatives* / Q000494:pharmacology; D004298:Dopamine / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005334:Fever / Q000139:chemically induced / Q000503:physiopathology; D008297:Male; D008314:Malonates / Q000494:pharmacology; D017551:Microdialysis; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000494:pharmacology*; D019331:NG-Nitroarginine Methyl Ester / Q000494:pharmacology; D017072:Neostriatum / Q000187:drug effects / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000037:antagonists & inhibitors; D009569:Nitric Oxide / Q000502:physiology*; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors; D052248:Nitric Oxide Synthase Type I; D030421:Peroxynitrous Acid / Q000494:pharmacology; D051381:Rats; D012701:Serotonin / Q000378:metabolism*; D018490:Serotonin Agents / Q000494:pharmacology*; D013890:Thiourea / Q000031:analogs & derivatives* / Q000494:pharmacology; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000378:metabolism
D004791:Enzyme Inhibitors; D008314:Malonates; D009419:Nerve Tissue Proteins; D018490:Serotonin Agents; D030421:Peroxynitrous Acid; D002956:Citrulline; D009569:Nitric Oxide; D012701:Serotonin; C002744:3-nitrotyrosine; D014443:Tyrosine; C030290:malonic acid; D019001:Nitric Oxide Synthase; D052248:Nitric Oxide Synthase Type I; C496322:Nos1 protein, rat; D013890:Thiourea; D018817:N-Methyl-3,4-methylenedioxyamphetamine; C086717:S-methylthiocitrulline; D019331:NG-Nitroarginine Methyl Ester; D004298:Dopamine