Analysis of the third transmembrane domain of the human type 1 angiotensin II receptor by cysteine scanning mutagenesis.
Martin
Stéphane S
SS
Department of Pharmacology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, Quebec J1H 5N4, Canada.
Boucard
Antony A
AA
Clément
Martin
M
Escher
Emanuel
E
Leduc
Richard
R
Guillemette
Gaétan
G
D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D019556:COS Cells; D003545:Cysteine / Q000737:chemistry*; D018076:DNA, Complementary / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005020:Ethyl Methanesulfonate / Q000031:analogs & derivatives* / Q000737:chemistry; D006801:Humans; D007202:Indicators and Reagents / Q000494:pharmacology; D007532:Isoleucine / Q000737:chemistry; D007700:Kinetics; D008024:Ligands; D008954:Models, Biological; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D009154:Mutation; D009841:Oligonucleotides / Q000737:chemistry; D011485:Protein Binding; D011487:Protein Conformation; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D044140:Receptor, Angiotensin, Type 1 / Q000737:chemistry* / Q000235:genetics; D014443:Tyrosine / Q000737:chemistry
D018076:DNA, Complementary; D007202:Indicators and Reagents; D008024:Ligands; D009841:Oligonucleotides; D044140:Receptor, Angiotensin, Type 1; C093171:methanethiosulfonate ethylammonium; D007532:Isoleucine; D014443:Tyrosine; D005020:Ethyl Methanesulfonate; D003545:Cysteine