title: Substrate analogs for the investigation of deoxyxylulose 5-phosphate reductoisomerase inhibition: synthesis and evaluation.
authors.affiliation: College of Pharmacy, Pharmacy Building. Rm. 203, Oregon State University, Corvallis, OR 97331-3507, USA.
authors.forename: Chanokporn
authors.initials: C
authors.lastname: Phaosiri
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Proteau
mesh_terms: D019747:Aldose-Ketose Isomerases / Q000037:antagonists & inhibitors* / Q000737:chemistry*; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry; D005578:Fosfomycin / Q000031:analogs & derivatives* / Q000737:chemistry; D009097:Multienzyme Complexes / Q000037:antagonists & inhibitors* / Q000737:chemistry*; D010088:Oxidoreductases / Q000037:antagonists & inhibitors* / Q000737:chemistry*; D011994:Recombinant Proteins / Q000037:antagonists & inhibitors / Q000737:chemistry; D013329:Structure-Activity Relationship; D013403:Sugar Phosphates / Q000138:chemical synthesis* / Q000737:chemistry; D046939:Synechocystis / Q000201:enzymology
chemical_list: D004791:Enzyme Inhibitors; D009097:Multienzyme Complexes; D011994:Recombinant Proteins; D013403:Sugar Phosphates; D005578:Fosfomycin; C024640:fosmidomycin; D010088:Oxidoreductases; C114231:1-deoxy-D-xylulose 5-phosphate reductoisomerase; D019747:Aldose-Ketose Isomerases