title: Enhancement of the antibody-dependent cellular cytotoxicity of low-fucose IgG1 Is independent of FcgammaRIIIa functional polymorphism.
authors.affiliation: Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Tokyo, Japan.
authors.forename: Rinpei
authors.initials: R
authors.lastname: Niwa
authors.forename: Shigeki
authors.initials: S
authors.lastname: Hatanaka
authors.forename: Emi
authors.initials: E
authors.lastname: Shoji-Hosaka
authors.forename: Mikiko
authors.initials: M
authors.lastname: Sakurada
authors.forename: Yukari
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Aya
authors.initials: A
authors.lastname: Uehara
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Yokoi
authors.forename: Kazuyasu
authors.initials: K
authors.lastname: Nakamura
authors.forename: Kenya
authors.initials: K
authors.lastname: Shitara
mesh_terms: D000483:Alleles; D000911:Antibodies, Monoclonal / Q000494:pharmacology; D058846:Antibodies, Monoclonal, Murine-Derived; D000912:Antibodies, Neoplasm / Q000737:chemistry; D000920:Antibody-Dependent Cell Cytotoxicity; D018951:Antigens, CD20 / Q000096:biosynthesis; D045744:Cell Line, Tumor; D004305:Dose-Response Relationship, Drug; D004797:Enzyme-Linked Immunosorbent Assay; D005643:Fucose / Q000737:chemistry* / Q000378:metabolism; D005838:Genotype; D006801:Humans; D007074:Immunoglobulin G / Q000737:chemistry*; D007694:Killer Cells, Natural / Q000166:cytology; D007963:Leukocytes, Mononuclear / Q000378:metabolism; D009000:Monocytes / Q000378:metabolism; D009504:Neutrophils / Q000166:cytology; D010641:Phenotype; D011110:Polymorphism, Genetic; D011485:Protein Binding; D017452:Receptors, IgG / Q000737:chemistry*; D011994:Recombinant Proteins / Q000737:chemistry; D000069283:Rituximab; D013997:Time Factors
chemical_list: D000911:Antibodies, Monoclonal; D058846:Antibodies, Monoclonal, Murine-Derived; D000912:Antibodies, Neoplasm; D018951:Antigens, CD20; D007074:Immunoglobulin G; D017452:Receptors, IgG; D011994:Recombinant Proteins; D005643:Fucose; D000069283:Rituximab