The effect of variable CYP3A5 expression on cyclosporine dosing, blood pressure and long-term graft survival in renal transplant patients.
Kreutz
Reinhold
R
Abteilung Klinische Pharmakologie, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany. Kreutz@medizin.fu-berlin.de
Zürcher
Heiko
H
Kain
Silke
S
Martus
Peter
P
Offermann
Gerd
G
Beige
Joachim
J
D000328:Adult; D000483:Alleles; D001483:Base Sequence; D001794:Blood Pressure; D016572:Cyclosporine / Q000008:administration & dosage*; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics*; D004247:DNA / Q000235:genetics; D005260:Female; D015870:Gene Expression; D006085:Graft Survival; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D007668:Kidney / Q000201:enzymology; D016030:Kidney Transplantation / Q000502:physiology*; D008297:Male; D008875:Middle Aged
D007166:Immunosuppressive Agents; D016572:Cyclosporine; D004247:DNA; D003577:Cytochrome P-450 Enzyme System; C104464:CYP3A protein, human; C510164:CYP3A5 protein, human; D051544:Cytochrome P-450 CYP3A