Synthesis and evaluation of a high relaxivity manganese(II)-based MRI contrast agent.
Troughton
Jeffrey S
JS
EPIX Medical Inc., 71 Rogers Street, Cambridge, Massachusetts 02142, USA.
Greenfield
Matthew T
MT
Greenwood
Jaclyn M
JM
Dumas
Stéphane
S
Wiethoff
Andrea J
AJ
Wang
Jufeng
J
Spiller
Marga
M
McMurry
Thomas J
TJ
Caravan
Peter
P
D000818:Animals; D003287:Contrast Media / Q000138:chemical synthesis / Q000737:chemistry / Q000493:pharmacokinetics; D004353:Drug Evaluation, Preclinical; D006801:Humans; D008279:Magnetic Resonance Imaging; D008345:Manganese / Q000097:blood / Q000737:chemistry*; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry / Q000493:pharmacokinetics; D011817:Rabbits; D012709:Serum Albumin / Q000737:chemistry; D013696:Temperature
D003287:Contrast Media; D009942:Organometallic Compounds; D012709:Serum Albumin; D008345:Manganese