Mechanism of differential inhibition of hepatic and pancreatic fatty acid ethyl ester synthase by inhibitors of serine-esterases: in vitro and cell culture studies.
Kaphalia
Bhupendra S
BS
Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0609, USA.
Mericle
Kelly A
KA
Ansari
G A S
GA
D000217:Acyltransferases / Q000037:antagonists & inhibitors*; D000818:Animals; D043182:Carboxylesterase / Q000037:antagonists & inhibitors / Q000378:metabolism; D045744:Cell Line, Tumor; D002802:Cholinesterases / Q000378:metabolism; D004950:Esterases / Q000037:antagonists & inhibitors*; D006801:Humans; D007202:Indicators and Reagents; D008099:Liver / Q000201:enzymology*; D017551:Microdialysis; D009596:Nitrophenols / Q000378:metabolism; D009943:Organophosphorus Compounds / Q000494:pharmacology; D010179:Pancreas / Q000201:enzymology*; D011753:Pyrones / Q000494:pharmacology; D012694:Serine / Q000378:metabolism; D013379:Substrate Specificity; D013552:Swine
D007202:Indicators and Reagents; D009596:Nitrophenols; D009943:Organophosphorus Compounds; D011753:Pyrones; C000516:2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide; D012694:Serine; C008642:4-nitrophenyl acetate; C037903:3-benzyl-6-chloro-2-pyrone; D000217:Acyltransferases; D004950:Esterases; D043182:Carboxylesterase; C043403:fatty acyl ethyl ester synthase; D002802:Cholinesterases