Membrane-permeant, DNA-binding agents alter intracellular trafficking and increase the transfection efficiency of complexed plasmid DNA.
Fong
Sylvia
S
California Pacific Medical Center Research Institute, San Francisco, CA 94115, USA.
Liu
Yong
Y
Heath
Timothy
T
Fong
Paul
P
Liggitt
Denny
D
Debs
Robert J
RJ
D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D006690:Bisbenzimidazole / Q000008:administration & dosage / Q000378:metabolism* / Q000494:pharmacology; D002460:Cell Line; D002463:Cell Membrane Permeability; D002467:Cell Nucleus / Q000737:chemistry / Q000378:metabolism*; D004247:DNA / Q000008:administration & dosage / Q000032:analysis / Q000378:metabolism; D015870:Gene Expression; D017930:Genes, Reporter; D007275:Injections, Intravenous; D008081:Liposomes / Q000737:chemistry / Q000378:metabolism; D008156:Luciferases / Q000032:analysis / Q000235:genetics; D051379:Mice; D008815:Mice, Inbred Strains; D009685:Nuclear Envelope / Q000187:drug effects / Q000502:physiology; D010957:Plasmids / Q000008:administration & dosage* / Q000737:chemistry / Q000378:metabolism; D011134:Polysaccharides / Q000494:pharmacology; D014018:Tissue Distribution; D014162:Transfection / Q000379:methods*
D008081:Liposomes; D011134:Polysaccharides; D004247:DNA; C007789:fucoidan; D008156:Luciferases; D006690:Bisbenzimidazole