The effect of a brominated flame retardant, tetrabromobisphenol-A, on free radical formation in human neutrophil granulocytes: the involvement of the MAP kinase pathway and protein kinase C.
Reistad
Trine
T
Norwegian Defence Research Establishment, Division for Protection, PO Box 25, N-2027 Kjeller, Norway. Trine.Reistad@ffi.no
Mariussen
Espen
E
Fonnum
Frode
F
D001559:Benzhydryl Compounds; D002118:Calcium / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005411:Flame Retardants / Q000633:toxicity*; D006801:Humans; D066298:In Vitro Techniques; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism*; D019255:NADPH Oxidases / Q000378:metabolism; D009504:Neutrophils / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D010636:Phenols / Q000633:toxicity; D010766:Phosphorylation; D011075:Polybrominated Biphenyls / Q000633:toxicity*; D011493:Protein Kinase C / Q000378:metabolism*; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000378:metabolism*; D013997:Time Factors; D000098826:Bisphenol A Compounds
D001559:Benzhydryl Compounds; D002118:Calcium; D005411:Flame Retardants; D020928:Mitogen-Activated Protein Kinases; D019255:NADPH Oxidases; D010636:Phenols; D011075:Polybrominated Biphenyls; D011493:Protein Kinase C; D011505:Protein-Tyrosine Kinases; D017382:Reactive Oxygen Species; C020806:tetrabromobisphenol A; C006780:bisphenol A; D000098826:Bisphenol A Compounds