Subtype selective substrates for histone deacetylases.
Heltweg
Birgit
B
Department of Pharmaceutical and Medicinal Chemistry, Westfälische Wilhelms-Universität Münster, Hittorfstrasse 58-62, 48149 Münster, Germany.
Dequiedt
Franck
F
Marshall
Brett L
BL
Brauch
Carsten
C
Yoshida
Minoru
M
Nishino
Norikazu
N
Verdin
Eric
E
Jung
Manfred
M
D000818:Animals; D006367:HeLa Cells; D006655:Histone Deacetylases / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D008239:Lysine / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000493:pharmacokinetics; D051381:Rats; D011994:Recombinant Proteins / Q000378:metabolism; D056564:Sirtuin 1; D037761:Sirtuins / Q000378:metabolism; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013379:Substrate Specificity
D011994:Recombinant Proteins; C447939:SIRT1 protein, human; D056564:Sirtuin 1; D037761:Sirtuins; D006655:Histone Deacetylases; D008239:Lysine