A 384-well cell-based phospho-ERK assay for dopamine D2 and D3 receptors.
Wong
Stephen K-F
SK
Department of Neuroscience, Pfizer Global Research Development, Pfizer Inc., Easter Point Road, Groton, CT 06340, USA. stephen_wong@groton.pfizer.com
D015415:Biomarkers / Q000032:analysis / Q000378:metabolism; D015153:Blotting, Western; D002478:Cells, Cultured; D004298:Dopamine / Q000378:metabolism / Q000494:pharmacology; D004790:Enzyme Induction / Q000187:drug effects; D006801:Humans; D007259:Infrared Rays; D007700:Kinetics; D020928:Mitogen-Activated Protein Kinases / Q000032:analysis / Q000276:immunology / Q000378:metabolism*; D010766:Phosphorylation; D011869:Radioligand Assay; D017448:Receptors, Dopamine D2 / Q000819:agonists / Q000235:genetics / Q000378:metabolism*; D050637:Receptors, Dopamine D3; D012680:Sensitivity and Specificity
D015415:Biomarkers; C493593:DRD3 protein, human; D017448:Receptors, Dopamine D2; D050637:Receptors, Dopamine D3; D020928:Mitogen-Activated Protein Kinases; D004298:Dopamine