Recurrent thrombophlebitis in a colon cancer patient with C677T heterozygous genotype for MTHFR treated with 5-fluorouracil-based adjuvant chemotherapy.
Schiavon
Gaia
G
Medical Oncology and Haematology, Campus Bio-Medico University, Via Emilio Longoni 83, IT-00155 Rome, Italy.
Vincenzi
Bruno
B
Santini
Daniele
D
Avvisati
Giuseppe
G
Tonini
Giuseppe
G
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D003110:Colonic Neoplasms / Q000188:drug therapy*; D005472:Fluorouracil / Q000008:administration & dosage / Q000009:adverse effects* / Q000378:metabolism; D005838:Genotype; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008297:Male; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics* / Q000494:pharmacology*; D012307:Risk Factors; D013924:Thrombophlebitis / Q000139:chemically induced* / Q000235:genetics*
D042965:Methylenetetrahydrofolate Reductase (NADPH2); D002955:Leucovorin; D005472:Fluorouracil