title: The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling.
authors.affiliation: Department of Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
authors.forename: Thijs J
authors.initials: TJ
authors.lastname: Hagenbeek
authors.forename: Marianne
authors.initials: M
authors.lastname: Naspetti
authors.forename: Fabrice
authors.initials: F
authors.lastname: Malergue
authors.forename: Fabien
authors.initials: F
authors.lastname: Garçon
authors.forename: Jacques A
authors.initials: JA
authors.lastname: Nunès
authors.forename: Kitty B J M
authors.initials: KB
authors.lastname: Cleutjens
authors.forename: Jan
authors.initials: J
authors.lastname: Trapman
authors.forename: Paul
authors.initials: P
authors.lastname: Krimpenfort
authors.forename: Hergen
authors.initials: H
authors.lastname: Spits
mesh_terms: D000818:Animals; D049109:Cell Proliferation; D002470:Cell Survival / Q000502:physiology; D017931:DNA Primers; D005434:Flow Cytometry; D005838:Genotype; D015151:Immunoblotting; D047468:Immunoprecipitation; D015851:Interleukin-7 / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D051059:PTEN Phosphohydrolase; D016133:Polymerase Chain Reaction; D017027:Protein Tyrosine Phosphatases / Q000378:metabolism* / Q000502:physiology; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology*; D013601:T-Lymphocytes / Q000502:physiology*; D013950:Thymus Gland / Q000378:metabolism* / Q000502:physiology; D025521:Tumor Suppressor Proteins / Q000378:metabolism* / Q000502:physiology
chemical_list: D017931:DNA Primers; D015851:Interleukin-7; D016693:Receptors, Antigen, T-Cell, alpha-beta; D025521:Tumor Suppressor Proteins; D017027:Protein Tyrosine Phosphatases; D051059:PTEN Phosphohydrolase; C487757:Pten protein, mouse