title: Mannose 6-phosphorylated proteins are required for tumor necrosis factor-induced apoptosis: defective response in I-cell disease fibroblasts.
authors.affiliation: INSERM U466, Centre Hospitalier Universitaire de Rangueil, 1 Avenue Jean Poulhès, TSA 50032, 31059 Toulouse cedex 9, France.
authors.forename: Claudine
authors.initials: C
authors.lastname: Tardy
authors.forename: Hélène
authors.initials: H
authors.lastname: Autefage
authors.forename: Virgine
authors.initials: V
authors.lastname: Garcia
authors.forename: Thierry
authors.initials: T
authors.lastname: Levade
authors.forename: Nathalie
authors.initials: N
authors.lastname: Andrieu-Abadie
mesh_terms: D000626:Aminopeptidases; D000818:Animals; D017209:Apoptosis; D002268:Carboxypeptidases / Q000737:chemistry; D002401:Cathepsin B / Q000378:metabolism; D056668:Cathepsin L; D002403:Cathepsins / Q000378:metabolism; D016923:Cell Death; D002461:Cell Line, Transformed; D002470:Cell Survival; D004396:Coloring Agents / Q000494:pharmacology; D003470:Culture Media / Q000494:pharmacology; D003546:Cysteine Endopeptidases; D045304:Cytochromes c / Q000378:metabolism; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; D004305:Dose-Response Relationship, Drug; D010450:Endopeptidases / Q000378:metabolism; D053222:Fas Ligand Protein; D005347:Fibroblasts / Q000378:metabolism*; D005434:Flow Cytometry; D006056:Golgi Apparatus / Q000378:metabolism; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000096:biosynthesis; D008214:Lymphocytes / Q000378:metabolism; D008247:Lysosomes / Q000378:metabolism / Q000648:ultrastructure; D008360:Mannosephosphates / Q000737:chemistry*; D008562:Membrane Glycoproteins / Q000378:metabolism; D051379:Mice; D008856:Microscopy, Fluorescence; D009081:Mucolipidoses / Q000378:metabolism*; D010641:Phenotype; D010766:Phosphorylation; D011994:Recombinant Proteins / Q000737:chemistry; D015398:Signal Transduction; D012867:Skin / Q000166:cytology; D013778:Tetrazolium Salts / Q000494:pharmacology; D013844:Thiazoles / Q000494:pharmacology; D013997:Time Factors; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*; D019014:fas Receptor / Q000096:biosynthesis
chemical_list: D004396:Coloring Agents; D003470:Culture Media; C505661:FASLG protein, human; D053222:Fas Ligand Protein; C505658:Fasl protein, mouse; D008360:Mannosephosphates; D008562:Membrane Glycoproteins; D011994:Recombinant Proteins; D013778:Tetrazolium Salts; D013844:Thiazoles; D014409:Tumor Necrosis Factor-alpha; D019014:fas Receptor; D018799:Intercellular Adhesion Molecule-1; C027693:mannose-6-phosphate; D045304:Cytochromes c; D002268:Carboxypeptidases; D002403:Cathepsins; D010450:Endopeptidases; D000626:Aminopeptidases; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; D003546:Cysteine Endopeptidases; D002401:Cathepsin B; C534281:CTSL protein, human; D056668:Cathepsin L; C534278:Ctsl protein, mouse; C022616:thiazolyl blue