Inhibitory effects of TRK-820 on systemic skin scratching induced by morphine in rhesus monkeys.
Wakasa
Yoshio
Y
Pharmacology and Toxicology Department, Ina Research Inc., 2148-188 Nishiminowa, Ina, Nagano 399-4501, Japan. wakasa@ina-research.co.jp
Fujiwara
Atsushi
A
Umeuchi
Hideo
H
Endoh
Takashi
T
Okano
Kiyoshi
K
Tanaka
Toshiaki
T
Nagase
Hiroshi
H
D019900:3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer / Q000008:administration & dosage / Q000627:therapeutic use; D000818:Animals; D004305:Dose-Response Relationship, Drug; D008253:Macaca mulatta; D009019:Morphinans / Q000008:administration & dosage / Q000627:therapeutic use*; D009020:Morphine / Q000009:adverse effects*; D009043:Motor Activity / Q000187:drug effects; D019370:Observation; D011537:Pruritus / Q000139:chemically induced* / Q000188:drug therapy*; D017473:Receptors, Opioid, kappa / Q000819:agonists; D013141:Spiro Compounds / Q000008:administration & dosage / Q000627:therapeutic use*; D018709:Statistics, Nonparametric
D009019:Morphinans; D017473:Receptors, Opioid, kappa; D013141:Spiro Compounds; C111212:TRK 820; D019900:3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; D009020:Morphine