Impact of E1a modifications on tumor-selective adenoviral replication and toxicity.
Sauthoff
Harald
H
Division of Pulmonary & Critical Care Medicine, New York University School of Medicine, New York, NY 10016, USA.
Pipiya
Teona
T
Heitner
Sheila
S
Chen
Shu
S
Bleck
Bertram
B
Reibman
Joan
J
Chang
William
W
Norman
Robert G
RG
Rom
William N
WN
Hay
John G
JG
D000256:Adenoviridae / Q000235:genetics*; D017500:Adenovirus E1A Proteins / Q000235:genetics* / Q000378:metabolism; D020816:Amino Acid Motifs / Q000235:genetics; D001665:Binding Sites / Q000235:genetics; D045744:Cell Line, Tumor; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors / Q000633:toxicity*; D006801:Humans; D047468:Immunoprecipitation; D009369:Neoplasms / Q000628:therapy*; D009687:Nuclear Proteins / Q000378:metabolism; D017434:Protein Structure, Tertiary / Q000235:genetics; D016160:Retinoblastoma Protein / Q000235:genetics / Q000378:metabolism; D016196:S Phase; D017384:Sequence Deletion; D015534:Trans-Activators / Q000378:metabolism; D014779:Virus Replication / Q000235:genetics*
D017500:Adenovirus E1A Proteins; D009687:Nuclear Proteins; D016160:Retinoblastoma Protein; D015534:Trans-Activators