title: SPR-based interaction studies with small molecular weight ligands using hAGT fusion proteins.
authors.affiliation: F. Hoffmann-La Roche Ltd, Pharmaceutical Research, Discovery Chemistry, CH-4070- Basel, Switzerland. walter.huber@roche.com
authors.forename: Walter
authors.initials: W
authors.lastname: Huber
authors.forename: Samantha
authors.initials: S
authors.lastname: Perspicace
authors.forename: Josiane
authors.initials: J
authors.lastname: Kohler
authors.forename: Francis
authors.initials: F
authors.lastname: Müller
authors.forename: Daniel
authors.initials: D
authors.lastname: Schlatter
mesh_terms: D002457:Cell Extracts; D000081406:Peptidyl-Prolyl Isomerase F; D021983:Cyclophilins / Q000378:metabolism; D016572:Cyclosporine / Q000378:metabolism; D004926:Escherichia coli / Q000235:genetics; D006801:Humans; D007700:Kinetics; D008024:Ligands; D015394:Molecular Structure; D008970:Molecular Weight; D019853:O(6)-Methylguanine-DNA Methyltransferase / Q000235:genetics / Q000378:metabolism*; D011485:Protein Binding; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism*; D020349:Surface Plasmon Resonance / Q000379:methods*
chemical_list: D002457:Cell Extracts; D000081406:Peptidyl-Prolyl Isomerase F; D008024:Ligands; D011993:Recombinant Fusion Proteins; D016572:Cyclosporine; D019853:O(6)-Methylguanine-DNA Methyltransferase; D021983:Cyclophilins