Membrane permeation characteristics of abacavir in human erythrocytes and human T-lymphoblastoid CD4+ CEM cells: comparison with (-)-carbovir.
Mahony
William B
WB
Division of Medicinal Chemistry, GlaxoSmithKline, Research Triangle Park, NC 27709, USA.
Domin
Barbara A
BA
Daluge
Susan M
SM
Zimmerman
Thomas P
TP
D019380:Anti-HIV Agents / Q000493:pharmacokinetics*; D001692:Biological Transport; D015496:CD4-Positive T-Lymphocytes / Q000378:metabolism*; D002463:Cell Membrane Permeability / Q000502:physiology; D015224:Dideoxynucleosides / Q000493:pharmacokinetics*; D004305:Dose-Response Relationship, Drug; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D000099227:Abacavir
D019380:Anti-HIV Agents; D015224:Dideoxynucleosides; D000099227:Abacavir; C057503:carbovir