Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes.
Grünblatt
E
E
Institute of Clinical Neurochemistry and National Parkinson Foundation Centre of Excellence Laboratories, Clinic and Policlinic for Psychiatry and Psychotherapy, University of Würzburg, Germany.
Mandel
S
S
Jacob-Hirsch
J
J
Zeligson
S
S
Amariglo
N
N
Rechavi
G
G
Li
J
J
Ravid
R
R
Roggendorf
W
W
Riederer
P
P
Youdim
M B H
MB
D000368:Aged; D000369:Aged, 80 and over; D002448:Cell Adhesion / Q000235:genetics; D003599:Cytoskeleton / Q000235:genetics; D005260:Female; D015870:Gene Expression; D020869:Gene Expression Profiling; D006360:Heat-Shock Proteins / Q000235:genetics; D006801:Humans; D007501:Iron / Q000378:metabolism; D008297:Male; D009097:Multienzyme Complexes / Q000235:genetics; D020411:Oligonucleotide Array Sequence Analysis; D018384:Oxidative Stress / Q000235:genetics; D010300:Parkinson Disease / Q000235:genetics*; D046988:Proteasome Endopeptidase Complex / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013378:Substantia Nigra / Q000502:physiology*; D044767:Ubiquitin-Protein Ligases / Q000235:genetics
D006360:Heat-Shock Proteins; D009097:Multienzyme Complexes; D007501:Iron; D044767:Ubiquitin-Protein Ligases; D046988:Proteasome Endopeptidase Complex