In vitro metabolism of cyclosporine A by human kidney CYP3A5.
Dai
Yang
Y
Department of Pharmaceutics, University of Washington, Seattle, WA 98195, USA.
Iwanaga
Kazunori
K
Lin
Yvonne S
YS
Hebert
Mary F
MF
Davis
Connie L
CL
Huang
Weili
W
Kharasch
Evan D
ED
Thummel
Kenneth E
KE
D001711:Biotransformation; D015153:Blotting, Western; D016572:Cyclosporine / Q000032:analysis / Q000378:metabolism*; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics / Q000378:metabolism*; D005838:Genotype; D006801:Humans; D007668:Kidney / Q000201:enzymology*; D007700:Kinetics; D008861:Microsomes / Q000378:metabolism; D013739:Testosterone / Q000378:metabolism
C098103:AM 19; D013739:Testosterone; D016572:Cyclosporine; D003577:Cytochrome P-450 Enzyme System; C104464:CYP3A protein, human; C510164:CYP3A5 protein, human; D051544:Cytochrome P-450 CYP3A; C510163:CYP3A4 protein, human