title: Novel PPARgamma agonists GI 262570, GW 7845, GW 1929, and pioglitazone decrease calcium channel function and myogenic tone in rat mesenteric arteries.
authors.affiliation: Department of Pharmacology, University of Vermont College of Medicine, Burlington, VT 05406-0068, USA.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Heppner
authors.forename: Adrian D
authors.initials: AD
authors.lastname: Bonev
authors.forename: Delrae M
authors.initials: DM
authors.lastname: Eckman
authors.forename: Maria F
authors.initials: MF
authors.lastname: Gomez
authors.forename: Georgi V
authors.initials: GV
authors.lastname: Petkov
authors.forename: Mark T
authors.initials: MT
authors.lastname: Nelson
mesh_terms: D000465:Algorithms; D000818:Animals; D001464:Barium / Q000037:antagonists & inhibitors; D001577:Benzophenones / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects; D015220:Calcium Channels / Q000187:drug effects* / Q000378:metabolism; D004594:Electrophysiology; D005260:Female; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects; D008638:Mesenteric Arteries / Q000166:cytology / Q000187:drug effects; D032342:Muscle Cells / Q000187:drug effects; D009129:Muscle Tonus / Q000187:drug effects*; D009131:Muscle, Smooth, Vascular / Q000166:cytology / Q000187:drug effects*; D010080:Oxazoles / Q000494:pharmacology*; D047495:PPAR gamma / Q000819:agonists*; D018408:Patch-Clamp Techniques; D000077205:Pioglitazone; D051381:Rats; D017207:Rats, Sprague-Dawley; D045162:Thiazolidinediones / Q000494:pharmacology*; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000494:pharmacology*; D014664:Vasodilation / Q000187:drug effects
chemical_list: D001577:Benzophenones; D015220:Calcium Channels; D007004:Hypoglycemic Agents; D010080:Oxazoles; D047495:PPAR gamma; D045162:Thiazolidinediones; C401311:GW 7845; D001464:Barium; C422415:farglitazar; D014443:Tyrosine; D000077205:Pioglitazone; C120099:GW 1929