title: 1.8A X-ray structure of C95M/C1095F double mutant of tethered HIV-1 protease dimer complexed with acetyl pepstatin.
authors.affiliation: Solid State Physics Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India.
authors.forename: Vishal
authors.initials: V
authors.lastname: Prashar
authors.forename: M V
authors.initials: MV
authors.lastname: Hosur
mesh_terms: D019943:Amino Acid Substitution; D001665:Binding Sites; D003198:Computer Simulation; D003460:Crystallization / Q000379:methods; D018360:Crystallography, X-Ray / Q000379:methods; D003545:Cysteine / Q000737:chemistry*; D019281:Dimerization; D004789:Enzyme Activation; D016333:HIV Protease / Q000737:chemistry*; D046911:Macromolecular Substances; D008956:Models, Chemical; D008958:Models, Molecular; D016297:Mutagenesis, Site-Directed; D009154:Mutation; D010436:Pepstatins / Q000737:chemistry*; D011485:Protein Binding; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D013329:Structure-Activity Relationship
chemical_list: D046911:Macromolecular Substances; D010436:Pepstatins; C014195:Streptomyces pepsin inhibitor; D016333:HIV Protease; D003545:Cysteine