title: The capacity of particles to increase allergic sensitization is predicted by particle number and surface area, not by particle mass.
authors.affiliation: Division of Environmental Medicine, Norwegian Institute of Public Health, PO Box 4404 Nydalen, NO-0403 Oslo, Norway. unni.cecilie.nygaard@fhi.no
authors.forename: Unni Cecilie
authors.initials: UC
authors.lastname: Nygaard
authors.forename: Mari
authors.initials: M
authors.lastname: Samuelsen
authors.forename: Audun
authors.initials: A
authors.lastname: Aase
authors.forename: Martinus
authors.initials: M
authors.lastname: Løvik
mesh_terms: D000276:Adjuvants, Immunologic; D000818:Animals; D000954:Antigens, Surface / Q000032:analysis; D002244:Carbon / Q000633:toxicity; D016207:Cytokines / Q000032:analysis / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006967:Hypersensitivity / Q000473:pathology*; D007073:Immunoglobulin E / Q000096:biosynthesis; D007074:Immunoglobulin G / Q000096:biosynthesis; D008198:Lymph Nodes / Q000276:immunology / Q000473:pathology; D018655:Lymphocyte Count; D008214:Lymphocytes / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D010047:Ovalbumin / Q000276:immunology; D010316:Particle Size; D010641:Phenotype; D011137:Polystyrenes / Q000633:toxicity; D011237:Predictive Value of Tests; D012044:Regression Analysis; D013499:Surface Properties; D013936:Thymidine / Q000378:metabolism; D001335:Vehicle Emissions / Q000633:toxicity
chemical_list: D000276:Adjuvants, Immunologic; D000954:Antigens, Surface; D016207:Cytokines; D007074:Immunoglobulin G; D011137:Polystyrenes; D001335:Vehicle Emissions; D007073:Immunoglobulin E; D002244:Carbon; D010047:Ovalbumin; D013936:Thymidine