Radiation-guided drug delivery to tumor blood vessels results in improved tumor growth delay.
Geng
Ling
L
Department of Radiation Oncology, Vanderbilt University, Nashville, TN 37232, USA.
Osusky
Katherine
K
Konjeti
Sekhar
S
Fu
Allie
A
Hallahan
Dennis
D
D020533:Angiogenesis Inhibitors / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D002945:Cisplatin / Q000494:pharmacology; D003131:Combined Modality Therapy / Q000379:methods*; D004195:Disease Models, Animal; D016503:Drug Delivery Systems / Q000379:methods*; D004354:Drug Screening Assays, Antitumor / Q000379:methods; D005260:Female; D016650:Fluorescein-5-isothiocyanate / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D007205:Indium Radioisotopes; D008081:Liposomes / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D051379:Mice; D008810:Mice, Inbred C57BL; D009369:Neoplasms / Q000532:radiotherapy*; D009374:Neoplasms, Experimental / Q000098:blood supply / Q000532:radiotherapy* / Q000648:ultrastructure; D017247:Neutron Capture Therapy; D011838:Radiation-Sensitizing Agents / Q000494:pharmacology; D011874:Radiometry / Q000009:adverse effects / Q000379:methods; D012867:Skin / Q000098:blood supply / Q000187:drug effects / Q000648:ultrastructure; D014407:Tumor Cells, Cultured; D014909:Wheat Germ Agglutinins / Q000378:metabolism / Q000494:pharmacology
D020533:Angiogenesis Inhibitors; D007205:Indium Radioisotopes; D008081:Liposomes; D011838:Radiation-Sensitizing Agents; D014909:Wheat Germ Agglutinins; C047939:fluorescein isothiocyanate-wheat germ agglutinin; D016650:Fluorescein-5-isothiocyanate; D002945:Cisplatin