Local anesthetics reduce mortality and protect against renal and hepatic dysfunction in murine septic peritonitis.
Gallos
George
G
Department of Anesthesiology, Columbia University, 630 West 168th Street, New York, NY 10032-3784, USA.
Jones
Dean R
DR
Nasr
Samih H
SH
Emala
Charles W
CW
Lee
H Thomas
HT
D000779:Anesthetics, Local / Q000627:therapeutic use*; D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D018925:Chemokines / Q000097:blood; D007668:Kidney / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D008099:Liver / Q000187:drug effects* / Q000502:physiology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D010538:Peritonitis / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D009195:Peroxidase / Q000378:metabolism; D018805:Sepsis / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis
D000779:Anesthetics, Local; D018925:Chemokines; D014409:Tumor Necrosis Factor-alpha; D009195:Peroxidase