title: Potent antiviral effect of reverset in HIV-1-infected adults following a single oral dose.
authors.affiliation: Pharmasset, Inc., Tucker, Ga., USA.
authors.forename: Lieven J
authors.initials: LJ
authors.lastname: Stuyver
authors.forename: Tamara R
authors.initials: TR
authors.lastname: McBrayer
authors.forename: Dirk
authors.initials: D
authors.lastname: Schürmann
authors.forename: Irena
authors.initials: I
authors.lastname: Kravec
authors.forename: Amanda
authors.initials: A
authors.lastname: Beard
authors.forename: Leanne
authors.initials: L
authors.lastname: Cartee
authors.forename: Raymond F
authors.initials: RF
authors.lastname: Schinazi
authors.forename: Abel
authors.initials: A
authors.lastname: De La Rosa
authors.forename: Robert L
authors.initials: RL
authors.lastname: Murphy
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Otto
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D015331:Cohort Studies; D003570:Cytidine Triphosphate / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000493:pharmacokinetics / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005838:Genotype; D015658:HIV Infections / Q000188:drug therapy* / Q000378:metabolism / Q000821:virology; D054303:HIV Reverse Transcriptase / Q000037:antagonists & inhibitors* / Q000235:genetics; D015497:HIV-1 / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008875:Middle Aged; D018894:Reverse Transcriptase Inhibitors / Q000493:pharmacokinetics / Q000627:therapeutic use*; D017423:Sequence Analysis, RNA; D019562:Viral Load; D016047:Zalcitabine / Q000031:analogs & derivatives
chemical_list: D018894:Reverse Transcriptase Inhibitors; D003570:Cytidine Triphosphate; D016047:Zalcitabine; D054303:HIV Reverse Transcriptase; C099405:dexelvucitabine