Beneficial effects of the sigma1 receptor agonists igmesine and dehydroepiandrosterone against learning impairments in rats prenatally exposed to cocaine.
Meunier
Johann
J
Laboratoire de Plasticité Cérébrale, CNRS FRE 2693, Université de Montpellier II, Place Eugène Bataillon, Montpellier cedex 534095, France.
Maurice
Tangui
T
D000818:Animals; D000831:Animals, Newborn; D001362:Avoidance Learning / Q000187:drug effects / Q000502:physiology; D001921:Brain / Q000187:drug effects / Q000378:metabolism / Q000503:physiopathology; D002934:Cinnamates / Q000627:therapeutic use*; D003042:Cocaine / Q000037:antagonists & inhibitors* / Q000633:toxicity; D003521:Cyclopropanes / Q000627:therapeutic use*; D003687:Dehydroepiandrosterone / Q000627:therapeutic use*; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D005260:Female; D007859:Learning Disabilities / Q000139:chemically induced / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D018782:Maze Learning / Q000187:drug effects / Q000502:physiology; D008569:Memory Disorders / Q000139:chemically induced / Q000188:drug therapy / Q000503:physiopathology; D010879:Piperazines / Q000494:pharmacology; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D017207:Rats, Sprague-Dawley; D017480:Receptors, sigma / Q000819:agonists* / Q000037:antagonists & inhibitors / Q000378:metabolism; D012727:Sex Characteristics; D000097605:Sigma-1 Receptor
D002934:Cinnamates; D003042:Cocaine; D003521:Cyclopropanes; D003687:Dehydroepiandrosterone; D010879:Piperazines; D017480:Receptors, sigma; D000097605:Sigma-1 Receptor; C093337:1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine; C065310:igmesine