Activation of dendritic cells and induction of T cell responses by HPV 16 L1/E7 chimeric virus-like particles are enhanced by CpG ODN or sorbitol.
Freyschmidt
Eva-Jasmin
EJ
Deutsches Krebsforschungszentrum, Heidelberg, Germany.
Alonso
Angel
A
Hartmann
Gunther
G
Gissmann
Lutz
L
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D018122:B7-1 Antigen / Q000096:biosynthesis; D001853:Bone Marrow / Q000187:drug effects / Q000276:immunology* / Q000821:virology; D019013:CD40 Antigens / Q000096:biosynthesis; D036022:Capsid Proteins / Q000235:genetics / Q000276:immunology; D002478:Cells, Cultured; D018899:CpG Islands; D003713:Dendritic Cells / Q000187:drug effects / Q000276:immunology* / Q000821:virology; D004306:Dose-Response Relationship, Immunologic; D018984:Epitopes, T-Lymphocyte / Q000096:biosynthesis; D005260:Female; D000949:Histocompatibility Antigens Class II / Q000096:biosynthesis; D018799:Intercellular Adhesion Molecule-1 / Q000096:biosynthesis; D008070:Lipopolysaccharides / Q000494:pharmacology; D008213:Lymphocyte Activation / Q000187:drug effects; D051379:Mice; D008810:Mice, Inbred C57BL; D009838:Oligodeoxyribonucleotides / Q000494:pharmacology*; D009856:Oncogene Proteins, Viral / Q000235:genetics / Q000276:immunology* / Q000494:pharmacology; D027383:Papillomaviridae / Q000472:pathogenicity*; D050725:Papillomavirus E7 Proteins; D013012:Sorbitol / Q000494:pharmacology*; D013602:T-Lymphocytes, Cytotoxic / Q000187:drug effects / Q000276:immunology* / Q000821:virology
D000276:Adjuvants, Immunologic; D018122:B7-1 Antigen; D019013:CD40 Antigens; D036022:Capsid Proteins; D018984:Epitopes, T-Lymphocyte; D000949:Histocompatibility Antigens Class II; D008070:Lipopolysaccharides; D009838:Oligodeoxyribonucleotides; D009856:Oncogene Proteins, Viral; D050725:Papillomavirus E7 Proteins; C059731:oncogene protein E7, Human papillomavirus type 16; D018799:Intercellular Adhesion Molecule-1; D013012:Sorbitol; C063317:L1 protein, Human papillomavirus type 16