title: Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain.
authors.affiliation: Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Jingshan
authors.initials: J
authors.lastname: Chen
authors.forename: Barbara K
authors.initials: BK
authors.lastname: Lipska
authors.forename: Nader
authors.initials: N
authors.lastname: Halim
authors.forename: Quang D
authors.initials: QD
authors.lastname: Ma
authors.forename: Mitsuyuki
authors.initials: M
authors.lastname: Matsumoto
authors.forename: Samer
authors.initials: S
authors.lastname: Melhem
authors.forename: Bhaskar S
authors.initials: BS
authors.lastname: Kolachana
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Hyde
authors.forename: Mary M
authors.initials: MM
authors.lastname: Herman
authors.forename: Jose
authors.initials: J
authors.lastname: Apud
authors.forename: Michael F
authors.initials: MF
authors.lastname: Egan
authors.forename: Joel E
authors.initials: JE
authors.lastname: Kleinman
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Weinberger
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D015153:Blotting, Western; D002394:Catechol O-Methyltransferase / Q000235:genetics*; D017931:DNA Primers; D015971:Gene Expression Regulation, Enzymologic / Q000502:physiology*; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D008214:Lymphocytes / Q000201:enzymology; D008745:Methylation; D051379:Mice; D016297:Mutagenesis, Site-Directed; D020641:Polymorphism, Single Nucleotide; D017397:Prefrontal Cortex / Q000201:enzymology* / Q000473:pathology; D011506:Proteins / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012737:Sex Factors
chemical_list: D017931:DNA Primers; D011506:Proteins; D012333:RNA, Messenger; D002394:Catechol O-Methyltransferase