Synthesis and biological evaluation of thiazolidine-2,4-dione and 2,4-thione derivatives as inhibitors of translation initiation.
Chen
Han
H
Laboratory for Translational Research, Harvard Medical School, Cambridge, MA 02139, USA.
Fan
Yun-Hua
YH
Natarajan
Amarnath
A
Guo
Yuhong
Y
Iyasere
Julia
J
Harbinski
Fred
F
Luus
Lia
L
Christ
William
W
Aktas
Huseyin
H
Halperin
Jose A
JA
D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002118:Calcium / Q000378:metabolism; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D015852:Eukaryotic Initiation Factor-2 / Q000378:metabolism; D006801:Humans; D010766:Phosphorylation; D014176:Protein Biosynthesis / Q000187:drug effects; D013329:Structure-Activity Relationship; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D045162:Thiazolidinediones; D013871:Thiones / Q000138:chemical synthesis* / Q000494:pharmacology; D013997:Time Factors; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D015852:Eukaryotic Initiation Factor-2; D013844:Thiazoles; D045162:Thiazolidinediones; D013871:Thiones; C500090:thiazolidine-2,4-dione; C500091:thiazolidine-2,4-thione; D002118:Calcium