Modeling the protonation states of the catalytic aspartates in beta-secretase.
Rajamani
Ramkumar
R
Johnson & Johnson Pharmaceutical R&D, Welsh and McKean Roads, PO Box 776, Spring House, PA 19477, USA.
Reynolds
Charles H
CH
D053829:Amyloid Precursor Protein Secretases; D001224:Aspartic Acid / Q000737:chemistry*; D002384:Catalysis; D020134:Catalytic Domain; D010450:Endopeptidases / Q000737:chemistry*; D004791:Enzyme Inhibitors / Q000737:chemistry; D008958:Models, Molecular; D011422:Propionates / Q000737:chemistry; D011522:Protons; D011789:Quantum Theory
D004791:Enzyme Inhibitors; D011422:Propionates; D011522:Protons; D001224:Aspartic Acid; D053829:Amyloid Precursor Protein Secretases; D010450:Endopeptidases; C029658:propionic acid