Intracellular sequestration of hetero-oligomers formed by wild-type and glaucoma-causing myocilin mutants.
Gobeil
Stéphane
S
Molecular Endocrinology and Oncology Research Center, Laval University Hospital (CHUL) Research Center, Québec City, Québec, Canada.
Rodrigue
Marc-André
MA
Moisan
Steve
S
Nguyen
Thai D
TD
Polansky
Jon R
JR
Morissette
Jean
J
Raymond
Vincent
V
D000818:Animals; D001082:Aqueous Humor / Q000378:metabolism; D015153:Blotting, Western; D019556:COS Cells; D002522:Chlorocebus aethiops; D003598:Cytoskeletal Proteins; D019281:Dimerization; D016326:Extracellular Matrix Proteins / Q000235:genetics* / Q000378:metabolism; D005136:Eye Proteins / Q000235:genetics* / Q000378:metabolism; D005902:Glaucoma, Open-Angle / Q000235:genetics* / Q000378:metabolism; D006023:Glycoproteins / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D016297:Mutagenesis, Site-Directed; D009154:Mutation; D014129:Trabecular Meshwork / Q000378:metabolism; D014162:Transfection; D000099179:Myocilin
D003598:Cytoskeletal Proteins; D016326:Extracellular Matrix Proteins; D005136:Eye Proteins; D006023:Glycoproteins; D000099179:Myocilin; C081451:olfactomedin