Induction of cyclooxygenase-2 in reactive glial cells by the CD40 pathway: relevance to amyotrophic lateral sclerosis.
Okuno
Tatsusada
T
Department of Neurology, Osaka University Graduate School of Medicine, Osaka, Japan.
Nakatsuji
Yuji
Y
Kumanogoh
Atsushi
A
Koguchi
Ken
K
Moriya
Masayuki
M
Fujimura
Harutoshi
H
Kikutani
Hitoshi
H
Sakoda
Saburo
S
D000690:Amyotrophic Lateral Sclerosis / Q000201:enzymology / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D019013:CD40 Antigens / Q000235:genetics / Q000378:metabolism* / Q000494:pharmacology; D051546:Cyclooxygenase 2; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology; D004195:Disease Models, Animal; D004790:Enzyme Induction / Q000187:drug effects / Q000502:physiology; D007527:Isoenzymes / Q000037:antagonists & inhibitors / Q000096:biosynthesis* / Q000235:genetics; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D008822:Mice, Transgenic; D009457:Neuroglia / Q000201:enzymology / Q000378:metabolism*; D009474:Neurons / Q000166:cytology / Q000201:enzymology / Q000378:metabolism; D011451:Prostaglandin-Endoperoxide Synthases / Q000096:biosynthesis* / Q000235:genetics; D015398:Signal Transduction / Q000502:physiology; D013119:Spinal Cord Injuries / Q000201:enzymology / Q000378:metabolism; D013482:Superoxide Dismutase / Q000235:genetics; D015854:Up-Regulation / Q000187:drug effects / Q000235:genetics
D019013:CD40 Antigens; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D007527:Isoenzymes; D051546:Cyclooxygenase 2; D011451:Prostaglandin-Endoperoxide Synthases; C109415:SOD1 G93A protein; D013482:Superoxide Dismutase