Thalidomide and pentoxifylline block the renal effects of supernatants of macrophages activated with Crotalus durissus cascavella venom.
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Departamento de Análises Clínicas e Toxicológicas, Instituto de Biomedicina e Unidade de Pesquisas Clínicas, Universidade Federal do Ceará, 60420-970 Fortaleza, Ceará, Brazil. martinsalice@hotmail.com
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D000818:Animals; D003435:Crotalid Venoms / Q000037:antagonists & inhibitors / Q000633:toxicity*; D005260:Female; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007668:Kidney / Q000187:drug effects*; D008262:Macrophage Activation / Q000187:drug effects; D017737:Macrophages, Peritoneal / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D010431:Pentoxifylline / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D013792:Thalidomide / Q000494:pharmacology*; D014409:Tumor Necrosis Factor-alpha / Q000187:drug effects / Q000378:metabolism*
D003435:Crotalid Venoms; D007166:Immunosuppressive Agents; D014409:Tumor Necrosis Factor-alpha; D013792:Thalidomide; D010431:Pentoxifylline