title: Structure/function analyses of human serum paraoxonase (HuPON1) mutants designed from a DFPase-like homology model.
authors.affiliation: Biochemical Pharmacology Branch, Pharmacology Division, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010-5400, USA.
authors.forename: David T
authors.initials: DT
authors.lastname: Yeung
authors.forename: Denis
authors.initials: D
authors.lastname: Josse
authors.forename: James D
authors.initials: JD
authors.lastname: Nicholson
authors.forename: Akhil
authors.initials: A
authors.lastname: Khanal
authors.forename: Christopher W
authors.initials: CW
authors.lastname: McAndrew
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Bahnson
authors.forename: David E
authors.initials: DE
authors.lastname: Lenz
authors.forename: Douglas M
authors.initials: DM
authors.lastname: Cerasoli
mesh_terms: D000818:Animals; D043303:Aryldialkylphosphatase / Q000097:blood / Q000737:chemistry* / Q000235:genetics*; D001483:Base Sequence; D020134:Catalytic Domain / Q000235:genetics; D002942:Circular Dichroism; D004247:DNA / Q000235:genetics; D049832:Decapodiformes / Q000201:enzymology; D006801:Humans; D066298:In Vitro Techniques; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D044345:Phosphoric Triester Hydrolases / Q000737:chemistry; D011487:Protein Conformation; D017433:Protein Structure, Secondary; D011994:Recombinant Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism
chemical_list: D011994:Recombinant Proteins; D004247:DNA; D044345:Phosphoric Triester Hydrolases; D043303:Aryldialkylphosphatase; C468406:PON1 protein, human; C020061:diisopropyl-fluorophosphatase