Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity.
Fewell
Sheara W
SW
Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.
Smith
Christine M
CM
Lyon
Michael A
MA
Dumitrescu
Teodora Pene
TP
Wipf
Peter
P
Day
Billy W
BW
Brodsky
Jeffrey L
JL
D000251:Adenosine Triphosphatases / Q000737:chemistry; D000255:Adenosine Triphosphate / Q000737:chemistry; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology; D001692:Biological Transport; D004305:Dose-Response Relationship, Drug; D006146:Guanidines / Q000494:pharmacology; D050956:HSP40 Heat-Shock Proteins; D018840:HSP70 Heat-Shock Proteins / Q000737:chemistry / Q000502:physiology*; D006360:Heat-Shock Proteins / Q000737:chemistry*; D006801:Humans; D006868:Hydrolysis; D008956:Models, Chemical; D008958:Models, Molecular; D018832:Molecular Chaperones / Q000737:chemistry*; D011485:Protein Binding; D011487:Protein Conformation; D011499:Protein Processing, Post-Translational; D021381:Protein Transport; D012984:Software; D013329:Structure-Activity Relationship; D013816:Thermodynamics; D013997:Time Factors
D000903:Antibiotics, Antineoplastic; C494647:DNAJB1 protein, human; D006146:Guanidines; D050956:HSP40 Heat-Shock Proteins; D018840:HSP70 Heat-Shock Proteins; D006360:Heat-Shock Proteins; D018832:Molecular Chaperones; D000255:Adenosine Triphosphate; D000251:Adenosine Triphosphatases; C037258:gusperimus