title: An N-terminal amphipathic helix in hepatitis C virus (HCV) NS4B mediates membrane association, correct localization of replication complex proteins, and HCV RNA replication.
authors.affiliation: Division of Gastroenterology and Hepatology, Stanford University School of Medicine, CCSR Building, Room 3115, 269 Campus Drive, Palo Alto, CA 94305-5187, USA.
authors.forename: Menashe
authors.initials: M
authors.lastname: Elazar
authors.forename: Ping
authors.initials: P
authors.lastname: Liu
authors.forename: Charles M
authors.initials: CM
authors.lastname: Rice
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Glenn
mesh_terms: D000595:Amino Acid Sequence; D045744:Cell Line, Tumor; D002462:Cell Membrane / Q000378:metabolism*; D015967:Gene Expression Regulation, Viral; D016174:Hepacivirus / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D008969:Molecular Sequence Data; D012367:RNA, Viral / Q000096:biosynthesis*; D012093:Replicon / Q000235:genetics* / Q000502:physiology; D017361:Viral Nonstructural Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D014779:Virus Replication
chemical_list: C093542:NS4 protein, hepatitis C virus; D012367:RNA, Viral; D017361:Viral Nonstructural Proteins