title: Vaccine protection from CD4+ T-cell loss caused by simian immunodeficiency virus (SIV) mac251 is afforded by sequential immunization with three unrelated vaccine vectors encoding multiple SIV antigens.
authors.affiliation: Department of Virology, Biomedical Primate Research Centre, Lange Kleiweg 139, 2288 GJ Rijswijk, the Netherlands.
authors.forename: Gerrit
authors.initials: G
authors.lastname: Koopman
authors.affiliation: Department of Virology, Biomedical Primate Research Centre, Lange Kleiweg 139, 2288 GJ Rijswijk, the Netherlands.
authors.forename: Daniella
authors.initials: D
authors.lastname: Mortier
authors.affiliation: Department of Virology, Biomedical Primate Research Centre, Lange Kleiweg 139, 2288 GJ Rijswijk, the Netherlands.
authors.forename: Sam
authors.initials: S
authors.lastname: Hofman
authors.affiliation: Department of Virology, Biomedical Primate Research Centre, Lange Kleiweg 139, 2288 GJ Rijswijk, the Netherlands.
authors.forename: Henk
authors.initials: H
authors.lastname: Niphuis
authors.affiliation: Department of Virology, Biomedical Primate Research Centre, Lange Kleiweg 139, 2288 GJ Rijswijk, the Netherlands.
authors.forename: Zahra
authors.initials: Z
authors.lastname: Fagrouch
authors.affiliation: Robert Koch Institut, Nordufer 20, D-13353 Berlin, Germany.
authors.forename: Steve
authors.initials: S
authors.lastname: Norley
authors.affiliation: GSF-Institut für Molekulare Virologie, Trogerstrasse 4b, 81675 München, Germany.
authors.forename: Gerd
authors.initials: G
authors.lastname: Sutter
authors.affiliation: Karolinska Institute, PO Box 280, SE-171 77 Solna, Sweden.
authors.forename: Peter
authors.initials: P
authors.lastname: Liljeström
authors.affiliation: Department of Virology, Biomedical Primate Research Centre, Lange Kleiweg 139, 2288 GJ Rijswijk, the Netherlands.
authors.forename: Jonathan L
authors.initials: JL
authors.lastname: Heeney
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D018791:CD4 Lymphocyte Count; D007114:Immunization; D007371:Interferon-gamma / Q000096:biosynthesis; D007376:Interleukin-2 / Q000096:biosynthesis; D015847:Interleukin-4 / Q000096:biosynthesis; D008253:Macaca mulatta; D018449:SAIDS Vaccines / Q000276:immunology*; D016097:Simian Acquired Immunodeficiency Syndrome / Q000276:immunology*; D014614:Vaccines, Synthetic / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D007376:Interleukin-2; D018449:SAIDS Vaccines; D014614:Vaccines, Synthetic; D015847:Interleukin-4; D007371:Interferon-gamma