title: The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin.
authors.affiliation: Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
authors.forename: Taiping
authors.initials: T
authors.lastname: Chen
authors.forename: Naomi
authors.initials: N
authors.lastname: Tsujimoto
authors.forename: En
authors.initials: E
authors.lastname: Li
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D004247:DNA / Q000378:metabolism; D004248:DNA (Cytosine-5-)-Methyltransferases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D019175:DNA Methylation; D000090205:DNA Methyltransferase 3A; D006570:Heterochromatin / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D051379:Mice; D018895:Microsatellite Repeats; D041681:NIH 3T3 Cells; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism; D013234:Stem Cells / Q000166:cytology / Q000502:physiology; D000097584:DNA Methyltransferase 3B
chemical_list: D004247:DNA; D004248:DNA (Cytosine-5-)-Methyltransferases; D000090205:DNA Methyltransferase 3A; D006570:Heterochromatin; D011993:Recombinant Fusion Proteins; D000097584:DNA Methyltransferase 3B; C000717967:DNMT3A protein, human; C000715535:Dnmt3a protein, mouse