Ectopic expression of tyrosinase increases melanin synthesis and cell death following UVB irradiation in fibroblasts from familial atypical multiple mole and melanoma (FAMMM) patients.
Yoneta
Akihiro
A
Department of Dermatology, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo 060-8543, Japan.
Yamashita
Toshiharu
T
Jin
Hai-Ying
HY
Kondo
Seiji
S
Jimbow
Kowichi
K
D000256:Adenoviridae / Q000235:genetics; D015153:Blotting, Western; D016923:Cell Death; D002470:Cell Survival; D004416:Dysplastic Nevus Syndrome / Q000235:genetics / Q000378:metabolism*; D005192:Family Health; D005347:Fibroblasts / Q000378:metabolism* / Q000528:radiation effects*; D005821:Genetic Techniques; D006801:Humans; D008543:Melanins / Q000096:biosynthesis* / Q000378:metabolism; D008545:Melanoma / Q000209:etiology / Q000378:metabolism*; D014442:Monophenol Monooxygenase / Q000096:biosynthesis* / Q000378:metabolism; D009508:Nevus, Pigmented / Q000378:metabolism*; D013997:Time Factors; D014443:Tyrosine / Q000378:metabolism; D014466:Ultraviolet Rays; D014983:Xeroderma Pigmentosum / Q000378:metabolism
D008543:Melanins; D014443:Tyrosine; D014442:Monophenol Monooxygenase