5-Amidinoindoles as dual inhibitors of coagulation factors IXa and Xa.
Batt
Douglas G
DG
Bristol-Myers Squibb Pharmaceutical Research Institute, PO Box 4000, Princeton, NJ 08543-4000, USA. douglas.batt@bms.com
Qiao
Jennifer X
JX
Modi
Dilip P
DP
Houghton
Gregory C
GC
Pierson
Deborah A
DA
Rossi
Karen A
KA
Luettgen
Joseph M
JM
Knabb
Robert M
RM
Jadhav
P K
PK
Wexler
Ruth R
RR
D015949:Factor IXa / Q000037:antagonists & inhibitors* / Q000737:chemistry*; D015951:Factor Xa / Q000737:chemistry*; D065427:Factor Xa Inhibitors; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013379:Substrate Specificity
D065427:Factor Xa Inhibitors; D007211:Indoles; C033570:5-amidinoindole; D015949:Factor IXa; D015951:Factor Xa