Novel cationic lipids incorporating an acid-sensitive acylhydrazone linker: synthesis and transfection properties.
Aissaoui
Abderrahim
A
INSERM U458, Hôpital Robert Debré, AP-HP, 48 Boulevard Sérurier, 75019 Paris, France.
Martin
Benjamin
B
Kan
Erwan
E
Oudrhiri
Noufissa
N
Hauchecorne
Michelle
M
Vigneron
Jean-Pierre
JP
Lehn
Jean-Marie
JM
Lehn
Pierre
P
D000818:Animals; D002412:Cations / Q000737:chemistry; D002460:Cell Line; D002783:Cholestenones / Q000138:chemical synthesis* / Q000737:chemistry / Q000633:toxicity; D004247:DNA / Q000008:administration & dosage; D005260:Female; D017930:Genes, Reporter; D006801:Humans; D006835:Hydrazones / Q000138:chemical synthesis* / Q000737:chemistry* / Q000633:toxicity; D006868:Hydrolysis; D007322:Instillation, Drug; D008055:Lipids / Q000138:chemical synthesis* / Q000737:chemistry / Q000633:toxicity; D008081:Liposomes; D008156:Luciferases / Q000096:biosynthesis / Q000235:genetics; D008168:Lung / Q000378:metabolism*; D051379:Mice; D008807:Mice, Inbred BALB C; D013329:Structure-Activity Relationship; D014162:Transfection
D002412:Cations; D002783:Cholestenones; D006835:Hydrazones; D008055:Lipids; D008081:Liposomes; C492969:bis(2-aminoethyl)amine hydrazone-cholest-4-enone; D004247:DNA; D008156:Luciferases