Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling.
Fernández-Monreal
Mónica
M
CNRS UMR 6185, University of Caen, Centre Cyceron, Bd. Henri Becquerel, BP 5229, 14074, Caen, France.
López-Atalaya
José P
JP
Benchenane
Karim
K
Cacquevel
Mathias
M
Dulin
Fabienne
F
Le Caer
Jean-Pierre
JP
Rossier
Jean
J
Jarrige
Anne-Charlotte
AC
Mackenzie
Eric T
ET
Colloc'h
Nathalie
N
Ali
Carine
C
Vivien
Denis
D
D000409:Alanine / Q000737:chemistry; D000595:Amino Acid Sequence; D000818:Animals; D001120:Arginine / Q000737:chemistry*; D001665:Binding Sites; D002118:Calcium / Q000737:chemistry; D002460:Cell Line; D006801:Humans; D015151:Immunoblotting; D007700:Kinetics; D008024:Ligands; D013058:Mass Spectrometry; D051379:Mice; D018715:Microscopy, Video; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D009154:Mutation; D009474:Neurons / Q000378:metabolism; D017354:Point Mutation; D011485:Protein Binding; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D016194:Receptors, N-Methyl-D-Aspartate / Q000737:chemistry* / Q000378:metabolism*; D011994:Recombinant Proteins / Q000737:chemistry; D017386:Sequence Homology, Amino Acid; D015398:Signal Transduction; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013696:Temperature; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000737:chemistry*; D014162:Transfection
D008024:Ligands; C409466:NR1 NMDA receptor; D016194:Receptors, N-Methyl-D-Aspartate; D011994:Recombinant Proteins; D001120:Arginine; D010959:Tissue Plasminogen Activator; D000409:Alanine; D002118:Calcium