title: Few amino acid positions in rpoB are associated with most of the rifampin resistance in Mycobacterium tuberculosis.
authors.affiliation: Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742-3360, USA. mike@umiacs.umd.edu.
authors.forename: Michael P
authors.initials: MP
authors.lastname: Cummings
authors.forename: Mark R
authors.initials: MR
authors.lastname: Segal
mesh_terms: D000596:Amino Acids / Q000502:physiology*; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D002965:Classification / Q000379:methods; D012321:DNA-Directed RNA Polymerases / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D004352:Drug Resistance, Microbial / Q000235:genetics*; D005838:Genotype; D008954:Models, Biological; D015233:Models, Statistical; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics; D010641:Phenotype; D011237:Predictive Value of Tests; D012044:Regression Analysis; D012293:Rifampin / Q000378:metabolism*
chemical_list: D000596:Amino Acids; D001426:Bacterial Proteins; D012321:DNA-Directed RNA Polymerases; C105078:RNA polymerase beta subunit; D012293:Rifampin