Reactivation of SYK expression by inhibition of DNA methylation suppresses breast cancer cell invasiveness.
Yuan
Yunfei
Y
Department of Molecular Pathology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.
Liu
Hongji
H
Sahin
Aysegul
A
Dai
Jia Le
JL
D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology; D001374:Azacitidine / Q000031:analogs & derivatives* / Q000494:pharmacology; D001940:Breast / Q000378:metabolism; D001943:Breast Neoplasms / Q000235:genetics / Q000517:prevention & control*; D044584:Carcinoma, Ductal / Q000235:genetics / Q000517:prevention & control; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000235:genetics / Q000517:prevention & control; D049109:Cell Proliferation / Q000187:drug effects; D019175:DNA Methylation; D015254:DNA Modification Methylases / Q000037:antagonists & inhibitors; D000077209:Decitabine; D004792:Enzyme Precursors / Q000037:antagonists & inhibitors* / Q000235:genetics* / Q000378:metabolism; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D020868:Gene Silencing; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D009361:Neoplasm Invasiveness / Q000517:prevention & control*; D010641:Phenotype; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors* / Q000235:genetics* / Q000378:metabolism; D013267:Stilbenes / Q000494:pharmacology; D000072377:Syk Kinase
D000964:Antimetabolites, Antineoplastic; D004792:Enzyme Precursors; D047908:Intracellular Signaling Peptides and Proteins; D013267:Stilbenes; C041525:3,3',4,5'-tetrahydroxystilbene; D000077209:Decitabine; D015254:DNA Modification Methylases; D011505:Protein-Tyrosine Kinases; C000606896:SYK protein, human; D000072377:Syk Kinase; D001374:Azacitidine