The protective effect of cyclosporin A upon N-acetylaspartate and mitochondrial dysfunction following experimental diffuse traumatic brain injury.
Signoretti
Stefano
S
Division of Neurosurgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298-0508, USA.
Marmarou
Anthony
A
Tavazzi
Barbara
B
Dunbar
Jana
J
Amorini
Angela M
AM
Lazzarino
Giuseppe
G
Vagnozzi
Roberto
R
D000818:Animals; D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000378:metabolism*; D001930:Brain Injuries / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D016572:Cyclosporine / Q000008:administration & dosage / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D007262:Infusions, Intravenous; D007278:Injections, Spinal; D008297:Male; D008928:Mitochondria / Q000187:drug effects* / Q000473:pathology*; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D051381:Rats; D017207:Rats, Sprague-Dawley
D018696:Neuroprotective Agents; D001224:Aspartic Acid; D016572:Cyclosporine; C000179:N-acetylaspartate