title: Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses.
authors.affiliation: Diabetes Endocrine Research Center, Fitkin 1, Yale School of Medicine, 333 Cedar St., New Haven, CT 06520, USA.
authors.forename: Mark L
authors.initials: ML
authors.lastname: Evans
authors.forename: Rory J
authors.initials: RJ
authors.lastname: McCrimmon
authors.forename: Daniel E
authors.initials: DE
authors.lastname: Flanagan
authors.forename: Tara
authors.initials: T
authors.lastname: Keshavarz
authors.forename: Xiaoning
authors.initials: X
authors.lastname: Fan
authors.forename: Ewan C
authors.initials: EC
authors.lastname: McNay
authors.forename: Ralph J
authors.initials: RJ
authors.lastname: Jacob
authors.forename: Robert S
authors.initials: RS
authors.lastname: Sherwin
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000187:drug effects / Q000378:metabolism*; D001921:Brain / Q000187:drug effects / Q000502:physiology*; D002096:C-Peptide / Q000097:blood; D002552:Cerebral Ventricles / Q000502:physiology; D005905:Glyburide / Q000008:administration & dosage / Q000494:pharmacology*; D007263:Infusions, Parenteral; D007328:Insulin / Q000097:blood; D008297:Male; D015221:Potassium Channels / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D014697:Ventromedial Hypothalamic Nucleus / Q000187:drug effects / Q000502:physiology*
chemical_list: D001786:Blood Glucose; D002096:C-Peptide; D007328:Insulin; D015221:Potassium Channels; D005905:Glyburide