Protective efficacy of a DNA influenza virus vaccine is markedly increased by the coadministration of a Schiff base-forming drug.
Charo
Jehad
J
Department of Oncology-Pathology, Cancer Center Karolinska (CCK), Karolinska Hospital, R8:01, S-171 76 Stockholm, Sweden. Jehad.Charo@mtc.ki.se
Lindencrona
Jan Alvar
JA
Carlson
Lena-Maria
LM
Hinkula
Jorma
J
Kiessling
Rolf
R
D000276:Adjuvants, Immunologic; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D001547:Benzaldehydes / Q000008:administration & dosage / Q000276:immunology*; D001565:Benzoates / Q000008:administration & dosage / Q000276:immunology*; D019267:Hemagglutinin Glycoproteins, Influenza Virus / Q000235:genetics / Q000276:immunology; D007114:Immunization; D007252:Influenza Vaccines / Q000008:administration & dosage / Q000276:immunology*; D051379:Mice; D009698:Nucleoproteins / Q000235:genetics / Q000276:immunology; D009976:Orthomyxoviridae Infections / Q000517:prevention & control*; D010957:Plasmids; D012545:Schiff Bases; D013601:T-Lymphocytes / Q000276:immunology; D018417:Th1 Cells / Q000276:immunology; D019444:Vaccines, DNA / Q000008:administration & dosage / Q000276:immunology*
D000276:Adjuvants, Immunologic; D000907:Antibodies, Bacterial; D001547:Benzaldehydes; D001565:Benzoates; D019267:Hemagglutinin Glycoproteins, Influenza Virus; D007252:Influenza Vaccines; D009698:Nucleoproteins; D012545:Schiff Bases; D019444:Vaccines, DNA; C059629:tucaresol