Directing flux in glycan biosynthetic pathways with a small molecule switch.
Kohler
Jennifer J
JJ
Department of Chemistry, University of California, Berkeley, B84 Hildebrand Hall, Berkeley, CA 94720, USA.
Czlapinski
Jennifer L
JL
Laughlin
Scott T
ST
Schelle
Michael W
MW
de Graffenried
Christopher L
CL
Bertozzi
Carolyn R
CR
D000818:Animals; D000942:Antigens, Bacterial / Q000187:drug effects / Q000378:metabolism; D016466:CHO Cells / Q000737:chemistry / Q000201:enzymology / Q000378:metabolism; D002384:Catalysis; D006224:Cricetinae; D005647:Fucosyltransferases / Q000187:drug effects / Q000378:metabolism*; D005700:Galactosyltransferases / Q000378:metabolism; D008970:Molecular Weight; D011134:Polysaccharides / Q000096:biosynthesis*; D017434:Protein Structure, Tertiary / Q000502:physiology; D020123:Sirolimus / Q000494:pharmacology; D000097631:Galactoside 2-alpha-L-fucosyltransferase
D000942:Antigens, Bacterial; D005647:Fucosyltransferases; D005700:Galactosyltransferases; D011134:Polysaccharides; D020123:Sirolimus; D000097631:Galactoside 2-alpha-L-fucosyltransferase; C022863:H antigen