Inhibitory effects of epicatechin on interleukin-1beta-induced inducible nitric oxide synthase expression in RINm5F cells and rat pancreatic islets by down-regulation of NF-kappaB activation.
Kim
Myung-Jun
MJ
Department of Physiology, College of Medicine, The Catholic University of Korea, Seoul 137-701, South Korea.
Ryu
Gyeong Ryul
GR
Kang
Jung-Hoon
JH
Sim
Sang Soo
SS
Min
Do Sik
DS
Rhie
Duck-Joo
DJ
Yoon
Shin Hee
SH
Hahn
Sang June
SJ
Jeong
In-Kyung
IK
Hong
Kyong-Ja
KJ
Kim
Myung-Suk
MS
Jo
Yang-Hyeok
YH
D000818:Animals; D002392:Catechin / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D015536:Down-Regulation; D015870:Gene Expression / Q000187:drug effects; D020672:I-kappa B Proteins / Q000378:metabolism / Q000494:pharmacology; D007328:Insulin / Q000378:metabolism; D007375:Interleukin-1 / Q000494:pharmacology*; D007515:Islets of Langerhans / Q000187:drug effects* / Q000201:enzymology; D000072000:NF-KappaB Inhibitor alpha; D016328:NF-kappa B / Q000378:metabolism*; D009569:Nitric Oxide / Q000378:metabolism; D019001:Nitric Oxide Synthase / Q000235:genetics / Q000378:metabolism*; D052247:Nitric Oxide Synthase Type II; D011401:Promoter Regions, Genetic / Q000187:drug effects / Q000502:physiology; D012333:RNA, Messenger / Q000187:drug effects / Q000378:metabolism; D051381:Rats
D020672:I-kappa B Proteins; D007328:Insulin; D007375:Interleukin-1; D016328:NF-kappa B; C000606206:Nfkbia protein, rat; D012333:RNA, Messenger; D000072000:NF-KappaB Inhibitor alpha; D009569:Nitric Oxide; D002392:Catechin; D019001:Nitric Oxide Synthase; D052247:Nitric Oxide Synthase Type II; C496318:Nos2 protein, rat