A nonradiometric, high-throughput assay for poly(ADP-ribose) glycohydrolase (PARG): application to inhibitor identification and evaluation.
Putt
Karson S
KS
Department of Biochemistry, University of Illinois, Urbana, IL 61801, USA.
Hergenrother
Paul J
PJ
D000818:Animals; D002138:Calibration; D002417:Cattle; D004791:Enzyme Inhibitors / Q000302:isolation & purification* / Q000494:pharmacology*; D004926:Escherichia coli / Q000235:genetics; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D011064:Poly Adenosine Diphosphate Ribose / Q000378:metabolism; D013949:Thymus Extracts / Q000378:metabolism
D004791:Enzyme Inhibitors; D013949:Thymus Extracts; D011064:Poly Adenosine Diphosphate Ribose; D006026:Glycoside Hydrolases; C022407:poly ADP-ribose glycohydrolase