Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells.
Cilenti
Lucia
L
Biomolecular Science Center, Burnett College of Biomedical Science, University of Central Florida, 12722 Research Parkway, Orlando, FL 32826, USA.
Kyriazis
George A
GA
Soundarapandian
Mangala M
MM
Stratico
Valerie
V
Yerkes
Adam
A
Park
Kwon Moo
KM
Sheridan
Alice M
AM
Alnemri
Emad S
ES
Bonventre
Joseph V
JV
Zervos
Antonis S
AS
D000818:Animals; D000970:Antineoplastic Agents / Q000633:toxicity*; D018929:Cell Culture Techniques; D016923:Cell Death / Q000187:drug effects* / Q000502:physiology*; D002945:Cisplatin / Q000633:toxicity*; D000074923:High-Temperature Requirement A Serine Peptidase 2; D006801:Humans; D007687:Kidney Tubules, Proximal / Q000166:cytology / Q000187:drug effects* / Q000473:pathology*; D051379:Mice; D008810:Mice, Inbred C57BL; D024101:Mitochondrial Proteins; D011506:Proteins / Q000378:metabolism; D012697:Serine Endopeptidases / Q000494:pharmacology*
D000970:Antineoplastic Agents; D024101:Mitochondrial Proteins; D011506:Proteins; D012697:Serine Endopeptidases; C000615914:HTRA2 protein, human; D000074923:High-Temperature Requirement A Serine Peptidase 2; C000615915:Htra2 protein, mouse; D002945:Cisplatin