Matrix GLA protein stimulates VEGF expression through increased transforming growth factor-beta1 activity in endothelial cells.
Boström
Kristina
K
Division of Cardiology, David Geffen School of Medicine, University of California, Box 951679, Rm. 47-123 CHS, Los Angeles, CA 90095-1679, USA. kbostrom@mednet.ucla.edu
Zebboudj
Amina F
AF
Yao
Yucheng
Y
Lin
Than S
TS
Torres
Alejandra
A
D000818:Animals; D001011:Aorta / Q000473:pathology; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins / Q000378:metabolism; D002135:Calcium-Binding Proteins / Q000378:metabolism / Q000502:physiology*; D002417:Cattle; D002465:Cell Movement; D049109:Cell Proliferation; D002478:Cells, Cultured; D003094:Collagen / Q000737:chemistry; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D042783:Endothelial Cells / Q000378:metabolism*; D016326:Extracellular Matrix Proteins / Q000378:metabolism / Q000502:physiology*; D016222:Fibroblast Growth Factor 2 / Q000378:metabolism; D017930:Genes, Reporter; D006801:Humans; D015151:Immunoblotting; D047468:Immunoprecipitation; D007797:Laminin / Q000737:chemistry; D008156:Luciferases / Q000378:metabolism; D010957:Plasmids / Q000378:metabolism; D011509:Proteoglycans / Q000737:chemistry; D012313:RNA / Q000737:chemistry / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013997:Time Factors; D014162:Transfection; D016212:Transforming Growth Factor beta / Q000378:metabolism*; D053773:Transforming Growth Factor beta1; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism*; D000097568:Matrix Gla Protein
D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins; D002135:Calcium-Binding Proteins; D003094:Collagen; D004338:Drug Combinations; D016326:Extracellular Matrix Proteins; D016222:Fibroblast Growth Factor 2; D007797:Laminin; D008156:Luciferases; D011509:Proteoglycans; D012313:RNA; D016212:Transforming Growth Factor beta; D053773:Transforming Growth Factor beta1; D042461:Vascular Endothelial Growth Factor A; D000097568:Matrix Gla Protein; C525718:BMP2 protein, human; C508960:TGFB1 protein, human; C059485:matrigel