Defective VLDL metabolism and severe atherosclerosis in mice expressing human apolipoprotein E isoforms but lacking the LDL receptor.
Knouff
Christopher
C
Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599-7525, USA.
Briand
Olivier
O
Lestavel
Sophie
S
Clavey
Veronique
V
Altenburg
Michael
M
Maeda
Nobuyo
N
D000818:Animals; D001011:Aorta / Q000378:metabolism / Q000473:pathology; D001057:Apolipoproteins E / Q000235:genetics / Q000378:metabolism*; D001161:Arteriosclerosis / Q000235:genetics / Q000378:metabolism*; D002478:Cells, Cultured; D015243:Cholesterol, VLDL / Q000378:metabolism*; D004032:Diet; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism; D005838:Genotype; D006801:Humans; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000097:blood; D008297:Male; D051379:Mice; D018345:Mice, Knockout; D011485:Protein Binding; D020033:Protein Isoforms / Q000235:genetics / Q000378:metabolism; D011973:Receptors, LDL / Q000235:genetics / Q000378:metabolism*
D001057:Apolipoproteins E; D015243:Cholesterol, VLDL; D008055:Lipids; D008074:Lipoproteins; D020033:Protein Isoforms; D011973:Receptors, LDL