A polymorphism in thrombospondin-1 associated with familial premature coronary artery disease alters Ca2+ binding.
Hannah
Blue-leaf A
BL
Department of Medicine, Medical Scientist Training Programs, University of Wisconsin, Madison, Wisconsin 53706, USA.
Misenheimer
Tina M
TM
Pranghofer
Michelle M
MM
Mosher
Deane F
DF
D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D001216:Asparagine / Q000737:chemistry; D001665:Binding Sites / Q000235:genetics; D002118:Calcium / Q000378:metabolism*; D003324:Coronary Artery Disease / Q000235:genetics* / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D020641:Polymorphism, Single Nucleotide; D011994:Recombinant Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D012694:Serine / Q000737:chemistry; D019700:Thrombospondin 1 / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*
D010446:Peptide Fragments; D011994:Recombinant Proteins; D019700:Thrombospondin 1; D012694:Serine; D001216:Asparagine; D002118:Calcium