Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise.
Mendell
Joshua T
JT
Institute of Genetic Medicine, Johns Hopkins University School of Medicine, 539 Broadway Research Building, 733 N. Broadway, Baltimore, Maryland 21205, USA.
Sharifi
Neda A
NA
Meyers
Jennifer L
JL
Martinez-Murillo
Francisco
F
Dietz
Harry C
HC
D000596:Amino Acids / Q000378:metabolism; D018389:Codon, Nonsense / Q000235:genetics; D016368:Frameshift Mutation; D005786:Gene Expression Regulation; D006367:HeLa Cells; D006801:Humans; D008969:Molecular Sequence Data; D020365:RNA Helicases; D012323:RNA Processing, Post-Transcriptional; D020871:RNA Stability; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D015534:Trans-Activators / Q000235:genetics
D000596:Amino Acids; D018389:Codon, Nonsense; D012333:RNA, Messenger; D015534:Trans-Activators; D020365:RNA Helicases; C101828:UPF1 protein, human