title: A novel pharmatope tag inserted into the beta4 subunit confers allosteric modulation to neuronal nicotinic receptors.
authors.affiliation: Department of Molecular Pharmacology, Physiology and Biotechnology, Brown Medical School, Providence, Rhode Island 02912, USA.
authors.forename: Tanya
authors.initials: T
authors.lastname: Sanders
authors.forename: Edward
authors.initials: E
authors.lastname: Hawrot
mesh_terms: D000495:Allosteric Site; D000818:Animals; D001665:Binding Sites; D001671:Biochemistry / Q000379:methods; D002038:Bungarotoxins / Q000494:pharmacology; D002462:Cell Membrane / Q000378:metabolism; D018360:Crystallography, X-Ray; D003545:Cysteine / Q000737:chemistry; D004594:Electrophysiology; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D018482:Muscle, Skeletal / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000737:chemistry* / Q000378:metabolism; D009474:Neurons / Q000378:metabolism; D009865:Oocytes / Q000378:metabolism; D010455:Peptides / Q000737:chemistry; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D018075:RNA, Complementary / Q000378:metabolism; D051381:Rats; D011978:Receptors, Nicotinic / Q000737:chemistry* / Q000378:metabolism; D013997:Time Factors; D014101:Torpedo; D014982:Xenopus laevis
chemical_list: D002038:Bungarotoxins; C486720:Chrnb4 protein, mouse; D009419:Nerve Tissue Proteins; D010455:Peptides; D018075:RNA, Complementary; D011978:Receptors, Nicotinic; D003545:Cysteine