Inhibitory targeting of checkpoint kinase signaling overrides radiation-induced cell cycle gene regulation: a therapeutic strategy in tumor cell radiosensitization?
Ree
Anne Hansen
AH
Department of Tumor Biology, The Norwegian Radium Hospital, 0310 Oslo, Norway.
Bratland
Ase
A
Nome
Ragnhild V
RV
Stokke
Trond
T
Fodstad
Oystein
O
Andersson
Yvonne
Y
D000818:Animals; D016923:Cell Death / Q000502:physiology; D045744:Cell Line, Tumor; D000071877:Checkpoint Kinase 1; D019926:Cyclin B / Q000502:physiology; D056744:Cyclin B1; D016195:G2 Phase / Q000502:physiology / Q000528:radiation effects*; D019398:Genes, BRCA1 / Q000502:physiology; D018816:Genes, cdc / Q000502:physiology / Q000528:radiation effects*; D011494:Protein Kinases / Q000502:physiology*; D011836:Radiation Tolerance / Q000502:physiology*; D015398:Signal Transduction
D019926:Cyclin B; D056744:Cyclin B1; D011494:Protein Kinases; D000071877:Checkpoint Kinase 1