Second-order advantage achieved with four-way fluorescence excitation-emission-kinetic data processed by parallel factor analysis and trilinear least-squares. Determination of methotrexate and leucovorin in human urine.
Olivieri
Alejandro C
AC
Departamento de Química Analítica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario S2002LRK, Argentina. aolivier@fbioyf.unr.edu.ar
Arancibia
Juan A
JA
Muñoz de la Peña
Arsenio
A
Durán-Merás
Isabel
I
Espinosa Mansilla
Anunciación
A
D006801:Humans; D007700:Kinetics; D016018:Least-Squares Analysis; D002955:Leucovorin / Q000737:chemistry / Q000652:urine*; D008727:Methotrexate / Q000737:chemistry / Q000652:urine*; D015394:Molecular Structure; D013050:Spectrometry, Fluorescence / Q000379:methods*; D013997:Time Factors
D002955:Leucovorin; D008727:Methotrexate