title: FHL3 negatively regulates human high-affinity IgE receptor beta-chain gene expression by acting as a transcriptional co-repressor of MZF-1.
authors.affiliation: Department of Molecular Cell Immunology and Allergology, Advanced Medical Research Center, Nihon University Graduate School of Medical Sciences, 30-1 Oyaguchi, Kami-machi, Itabashi-ku, Toyko 173-8610, Japan.
authors.forename: Kyoko
authors.initials: K
authors.lastname: Takahashi
authors.forename: Chiyuki
authors.initials: C
authors.lastname: Matsumoto
authors.forename: Chisei
authors.initials: C
authors.lastname: Ra
mesh_terms: D045744:Cell Line, Tumor; D002467:Cell Nucleus / Q000737:chemistry; D002850:Chromatography, Gel; D018076:DNA, Complementary / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics / Q000502:physiology*; D015536:Down-Regulation / Q000187:drug effects / Q000502:physiology; D017930:Genes, Reporter; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000494:pharmacology; D006801:Humans; D007377:Interleukin-3 / Q000494:pharmacology; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics / Q000502:physiology*; D007438:Introns / Q000235:genetics; D051741:Kruppel-Like Transcription Factors; D060588:LIM Domain Proteins; D015471:Leukemia, Basophilic, Acute / Q000473:pathology; D008969:Molecular Sequence Data; D005810:Multigene Family; D011401:Promoter Regions, Genetic / Q000235:genetics; D011485:Protein Binding; D025941:Protein Interaction Mapping; D017434:Protein Structure, Tertiary; D021381:Protein Transport; D017455:Receptors, IgE / Q000096:biosynthesis / Q000235:genetics*; D011993:Recombinant Fusion Proteins / Q000502:physiology; D012097:Repressor Proteins / Q000235:genetics / Q000502:physiology*; D012441:Saccharomyces cerevisiae / Q000378:metabolism; D014157:Transcription Factors / Q000235:genetics / Q000502:physiology*; D014158:Transcription, Genetic / Q000187:drug effects / Q000502:physiology*; D014170:Transformation, Genetic; D020798:Two-Hybrid System Techniques; D016335:Zinc Fingers / Q000235:genetics / Q000502:physiology
chemical_list: D018076:DNA, Complementary; D004268:DNA-Binding Proteins; C117563:FHL3 protein, human; D007377:Interleukin-3; D047908:Intracellular Signaling Peptides and Proteins; D051741:Kruppel-Like Transcription Factors; D060588:LIM Domain Proteins; C502447:MS4A2 protein, human; C085969:MZF1 protein, human; D017455:Receptors, IgE; D011993:Recombinant Fusion Proteins; D012097:Repressor Proteins; D014157:Transcription Factors; D016178:Granulocyte-Macrophage Colony-Stimulating Factor