title: Benzothienyloxy phenylpropanamines, novel dual inhibitors of serotonin and norepinephrine reuptake.
authors.affiliation: Eli Lilly and Company Ltd., Lilly Research Centre, Windlesham, Surrey GU20 6PH, UK.
authors.forename: J R
authors.initials: JR
authors.lastname: Boot
authors.forename: G
authors.initials: G
authors.lastname: Brace
authors.forename: C L
authors.initials: CL
authors.lastname: Delatour
authors.forename: N
authors.initials: N
authors.lastname: Dezutter
authors.forename: J
authors.initials: J
authors.lastname: Fairhurst
authors.forename: J
authors.initials: J
authors.lastname: Findlay
authors.forename: P T
authors.initials: PT
authors.lastname: Gallagher
authors.forename: I
authors.initials: I
authors.lastname: Hoes
authors.forename: S
authors.initials: S
authors.lastname: Mahadevan
authors.forename: S N
authors.initials: SN
authors.lastname: Mitchell
authors.forename: R E
authors.initials: RE
authors.lastname: Rathmell
authors.forename: S J
authors.initials: SJ
authors.lastname: Richards
authors.forename: R G
authors.initials: RG
authors.lastname: Simmonds
authors.forename: L
authors.initials: L
authors.lastname: Wallace
authors.forename: M A
authors.initials: MA
authors.lastname: Whatton
mesh_terms: D018759:Adrenergic Uptake Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology; D000928:Antidepressive Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D050483:Dopamine Plasma Membrane Transport Proteins; D006801:Humans; D066298:In Vitro Techniques; D008562:Membrane Glycoproteins / Q000378:metabolism; D026901:Membrane Transport Proteins / Q000378:metabolism; D008862:Microsomes, Liver / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000378:metabolism; D009638:Norepinephrine / Q000037:antagonists & inhibitors* / Q000378:metabolism; D050484:Norepinephrine Plasma Membrane Transport Proteins; D011437:Propylamines / Q000138:chemical synthesis* / Q000494:pharmacology; D050486:Serotonin Plasma Membrane Transport Proteins; D017367:Selective Serotonin Reuptake Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D027981:Symporters / Q000378:metabolism; D013876:Thiophenes / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D018759:Adrenergic Uptake Inhibitors; D000928:Antidepressive Agents; D050483:Dopamine Plasma Membrane Transport Proteins; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; D009638:Norepinephrine; D050484:Norepinephrine Plasma Membrane Transport Proteins; D011437:Propylamines; D050486:Serotonin Plasma Membrane Transport Proteins; D017367:Selective Serotonin Reuptake Inhibitors; D027981:Symporters; D013876:Thiophenes; C493227:SLC6A2 protein, human; C493230:SLC6A4 protein, human