title: Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: critical residues for DNA binding and hyperactivity in mammalian cells.
authors.affiliation: Stanford University, Department of Pediatrics, 300 Pasteur Dr., Room G305, Stanford, CA 94305-5208, USA.
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Yant
authors.forename: Julie
authors.initials: J
authors.lastname: Park
authors.forename: Yong
authors.initials: Y
authors.lastname: Huang
authors.forename: Jacob Giehm
authors.initials: JG
authors.lastname: Mikkelsen
authors.forename: Mark A
authors.initials: MA
authors.lastname: Kay
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D004247:DNA / Q000378:metabolism*; D004252:DNA Mutational Analysis; D004251:DNA Transposable Elements; D006367:HeLa Cells; D006801:Humans; D051379:Mice; D008810:Mice, Inbred C57BL; D016513:Mice, SCID; D008969:Molecular Sequence Data; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D019895:Transposases / Q000235:genetics* / Q000378:metabolism*
chemical_list: D004251:DNA Transposable Elements; D004247:DNA; D019895:Transposases; C494471:sleeping beauty transposase, human