title: The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector.
authors.affiliation: Peptide Biology Laboratories, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
authors.forename: Robert A
authors.initials: RA
authors.lastname: Screaton
authors.forename: Michael D
authors.initials: MD
authors.lastname: Conkright
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Katoh
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Best
authors.forename: Gianluca
authors.initials: G
authors.lastname: Canettieri
authors.forename: Shawn
authors.initials: S
authors.lastname: Jeffries
authors.forename: Ernesto
authors.initials: E
authors.lastname: Guzman
authors.forename: Sherry
authors.initials: S
authors.lastname: Niessen
authors.forename: John R
authors.initials: JR
authors.lastname: Yates
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takemori
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Okamoto
authors.forename: Marc
authors.initials: M
authors.lastname: Montminy
mesh_terms: D048948:14-3-3 Proteins / Q000378:metabolism; D021581:Active Transport, Cell Nucleus / Q000235:genetics; D000818:Animals; D019703:Calcineurin / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism; D020013:Calcium Signaling / Q000502:physiology*; D002460:Cell Line; D000242:Cyclic AMP / Q000378:metabolism*; D017362:Cyclic AMP Response Element-Binding Protein / Q000378:metabolism*; D005786:Gene Expression Regulation / Q000235:genetics; D005947:Glucose / Q000378:metabolism; D006728:Hormones / Q000378:metabolism; D006801:Humans; D007515:Islets of Langerhans / Q000378:metabolism; D046911:Macromolecular Substances; D051379:Mice; D010750:Phosphoproteins / Q000235:genetics / Q000378:metabolism*; D010766:Phosphorylation; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D034741:RNA, Small Interfering; D015398:Signal Transduction / Q000502:physiology; D015534:Trans-Activators / Q000235:genetics / Q000378:metabolism*; D014157:Transcription Factors
chemical_list: D048948:14-3-3 Proteins; C493245:CRTC2 protein, human; D017362:Cyclic AMP Response Element-Binding Protein; D006728:Hormones; D046911:Macromolecular Substances; D010750:Phosphoproteins; D034741:RNA, Small Interfering; D015534:Trans-Activators; D014157:Transcription Factors; D000242:Cyclic AMP; C474808:salt-inducible kinase-2, mouse; D017346:Protein Serine-Threonine Kinases; D019703:Calcineurin; D005947:Glucose; D002118:Calcium