Cyclin-dependent kinase activity is required at early times for accurate processing and accumulation of the human cytomegalovirus UL122-123 and UL37 immediate-early transcripts and at later times for virus production.
Sanchez
Veronica
V
Molecular Biology Section, Mail Code 0366, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0366, USA.
McElroy
Anita K
AK
Yen
Judy
J
Tamrakar
Sama
S
Clark
Charles L
CL
Schwartz
Rachel A
RA
Spector
Deborah H
DH
D001483:Base Sequence; D002478:Cells, Cultured; D018844:Cyclin-Dependent Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D003587:Cytomegalovirus / Q000378:metabolism / Q000502:physiology*; D005347:Fibroblasts / Q000821:virology; D015967:Gene Expression Regulation, Viral; D006801:Humans; D017874:Immediate-Early Proteins / Q000235:genetics / Q000378:metabolism*; D008969:Molecular Sequence Data; D011687:Purines / Q000494:pharmacology; D000077546:Roscovitine; D015534:Trans-Activators / Q000235:genetics / Q000378:metabolism*; D014158:Transcription, Genetic; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism*; D014779:Virus Replication
C069186:IE2 protein, Cytomegalovirus; D017874:Immediate-Early Proteins; D011687:Purines; D015534:Trans-Activators; C420323:UL37 protein, Human herpesvirus 5; D014764:Viral Proteins; D000077546:Roscovitine; D018844:Cyclin-Dependent Kinases