mTOR cascade activation distinguishes tubers from focal cortical dysplasia.
Baybis
Marianna
M
PENN Epilepsy Center and Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA.
Yu
Jia
J
Lee
Allana
A
Golden
Jeff A
JA
Weiner
Howard
H
McKhann
Guy
G
Aronica
Eleonora
E
Crino
Peter B
PB
D000293:Adolescent; D000328:Adult; D002452:Cell Count / Q000379:methods; D002540:Cerebral Cortex / Q000378:metabolism / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D004268:DNA-Binding Proteins / Q000378:metabolism; D004827:Epilepsy / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D039642:Eukaryotic Initiation Factors / Q000378:metabolism; D005260:Female; D005786:Gene Expression Regulation; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D017403:In Situ Hybridization / Q000379:methods; D007223:Infant; D007335:Insulin-Like Growth Factor II / Q000235:genetics / Q000378:metabolism; D008297:Male; D042282:Microdissection / Q000379:methods; D011494:Protein Kinases / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D012333:RNA, Messenger / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods; D038601:Ribosomal Protein S6 / Q000378:metabolism; D038762:Ribosomal Protein S6 Kinases, 70-kDa / Q000378:metabolism; D050796:STAT3 Transcription Factor; D058570:TOR Serine-Threonine Kinases; D015534:Trans-Activators / Q000378:metabolism; D016212:Transforming Growth Factor beta / Q000235:genetics / Q000378:metabolism; D014402:Tuberous Sclerosis / Q000235:genetics / Q000378:metabolism / Q000473:pathology*
D004268:DNA-Binding Proteins; D039642:Eukaryotic Initiation Factors; D012333:RNA, Messenger; D038601:Ribosomal Protein S6; D050796:STAT3 Transcription Factor; C494086:STAT3 protein, human; D015534:Trans-Activators; D016212:Transforming Growth Factor beta; D007335:Insulin-Like Growth Factor II; D011494:Protein Kinases; C546842:MTOR protein, human; D038762:Ribosomal Protein S6 Kinases, 70-kDa; D058570:TOR Serine-Threonine Kinases