title: Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells.
authors.affiliation: Biomolecular Science Center, Burnett College of Biomedical Science, University of Central Florida, 12722 Research Parkway, Orlando, FL 32826, USA.
authors.forename: Lucia
authors.initials: L
authors.lastname: Cilenti
authors.forename: George A
authors.initials: GA
authors.lastname: Kyriazis
authors.forename: Mangala M
authors.initials: MM
authors.lastname: Soundarapandian
authors.forename: Valerie
authors.initials: V
authors.lastname: Stratico
authors.forename: Adam
authors.initials: A
authors.lastname: Yerkes
authors.forename: Kwon Moo
authors.initials: KM
authors.lastname: Park
authors.forename: Alice M
authors.initials: AM
authors.lastname: Sheridan
authors.forename: Emad S
authors.initials: ES
authors.lastname: Alnemri
authors.forename: Joseph V
authors.initials: JV
authors.lastname: Bonventre
authors.forename: Antonis S
authors.initials: AS
authors.lastname: Zervos
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000633:toxicity*; D018929:Cell Culture Techniques; D016923:Cell Death / Q000187:drug effects* / Q000502:physiology*; D002945:Cisplatin / Q000633:toxicity*; D000074923:High-Temperature Requirement A Serine Peptidase 2; D006801:Humans; D007687:Kidney Tubules, Proximal / Q000166:cytology / Q000187:drug effects* / Q000473:pathology*; D051379:Mice; D008810:Mice, Inbred C57BL; D024101:Mitochondrial Proteins; D011506:Proteins / Q000378:metabolism; D012697:Serine Endopeptidases / Q000494:pharmacology*
chemical_list: D000970:Antineoplastic Agents; D024101:Mitochondrial Proteins; D011506:Proteins; D012697:Serine Endopeptidases; C000615914:HTRA2 protein, human; D000074923:High-Temperature Requirement A Serine Peptidase 2; C000615915:Htra2 protein, mouse; D002945:Cisplatin