title: Up-regulation of microsomal prostaglandin E synthase 1 in osteoarthritic human cartilage: critical roles of the ERK-1/2 and p38 signaling pathways.
authors.affiliation: UMR CNRS 7079, Université Pierre et Marie Curie (Paris VI), Paris, France.
authors.forename: Kayo
authors.initials: K
authors.lastname: Masuko-Hongo
authors.forename: Francis
authors.initials: F
authors.lastname: Berenbaum
authors.forename: Lydie
authors.initials: L
authors.lastname: Humbert
authors.forename: Colette
authors.initials: C
authors.lastname: Salvat
authors.forename: Mary B
authors.initials: MB
authors.lastname: Goldring
authors.forename: Sylvie
authors.initials: S
authors.lastname: Thirion
mesh_terms: D002358:Cartilage, Articular / Q000276:immunology*; D002460:Cell Line; D019902:Chondrocytes / Q000276:immunology; D006801:Humans; D007375:Interleukin-1 / Q000276:immunology; D019746:Intramolecular Oxidoreductases / Q000096:biosynthesis* / Q000276:immunology; D019950:Mitogen-Activated Protein Kinase 1 / Q000276:immunology; D048052:Mitogen-Activated Protein Kinase 3; D020928:Mitogen-Activated Protein Kinases / Q000276:immunology*; D010003:Osteoarthritis / Q000276:immunology*; D000071876:Prostaglandin-E Synthases; D015398:Signal Transduction / Q000276:immunology; D015854:Up-Regulation / Q000276:immunology; D048051:p38 Mitogen-Activated Protein Kinases
chemical_list: D007375:Interleukin-1; D019950:Mitogen-Activated Protein Kinase 1; D048052:Mitogen-Activated Protein Kinase 3; D020928:Mitogen-Activated Protein Kinases; D048051:p38 Mitogen-Activated Protein Kinases; D019746:Intramolecular Oxidoreductases; C000605862:PTGES protein, human; D000071876:Prostaglandin-E Synthases