title: Generation of novel conditional and hypomorphic alleles of the Smad2 gene.
authors.affiliation: Molecular, Cellular, and Developmental Biology Program, The Ohio State University, Columbus, OH 43210, USA.
authors.forename: Ye
authors.initials: Y
authors.lastname: Liu
authors.forename: Maria H
authors.initials: MH
authors.lastname: Festing
authors.forename: Mark
authors.initials: M
authors.lastname: Hester
authors.forename: John C
authors.initials: JC
authors.lastname: Thompson
authors.forename: Michael
authors.initials: M
authors.lastname: Weinstein
mesh_terms: D000483:Alleles; D019943:Amino Acid Substitution; D000818:Animals; D015153:Blotting, Western; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D004268:DNA-Binding Proteins / Q000235:genetics* / Q000378:metabolism*; D004622:Embryo, Mammalian / Q000166:cytology / Q000378:metabolism; D004625:Embryo, Nonmammalian; D047108:Embryonic Development; D000939:Epitopes; D005091:Exons; D017353:Gene Deletion; D018390:Gene Targeting; D005818:Genetic Engineering / Q000379:methods; D005822:Genetic Vectors; D006720:Homozygote; D019426:Integrases; D007438:Introns; D051379:Mice; D008845:Microinjections; D009030:Mosaicism; D009154:Mutation; D016133:Polymerase Chain Reaction; D011995:Recombination, Genetic; D051899:Smad2 Protein; D013234:Stem Cells; D015534:Trans-Activators / Q000235:genetics* / Q000378:metabolism*; D014764:Viral Proteins; D014981:Xenopus; D029867:Xenopus Proteins; D001616:beta-Galactosidase / Q000378:metabolism
chemical_list: D004268:DNA-Binding Proteins; D000939:Epitopes; D051899:Smad2 Protein; C497785:Smad2 protein, Xenopus; C497783:Smad2 protein, mouse; D015534:Trans-Activators; D014764:Viral Proteins; D029867:Xenopus Proteins; C045073:Cre recombinase; D019426:Integrases; D001616:beta-Galactosidase