Inhibition of isoprene biosynthesis pathway enzymes by phosphonates, bisphosphonates, and diphosphates.
Cheng
Feng
F
Departments of Chemistry and Biophysics, 600 South Mathews Avenue, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Oldfield
Eric
E
D019747:Aldose-Ketose Isomerases / Q000737:chemistry*; D000465:Algorithms; D019883:Alkyl and Aryl Transferases / Q000737:chemistry*; D001665:Binding Sites; D019748:Carbon-Carbon Double Bond Isomerases / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004164:Diphosphonates / Q000737:chemistry; D051228:Geranyltranstransferase; D045782:Hemiterpenes; D008024:Ligands; D008958:Models, Molecular; D008968:Molecular Conformation; D009097:Multienzyme Complexes / Q000737:chemistry*; D063065:Organophosphonates / Q000737:chemistry; D009943:Organophosphorus Compounds / Q000737:chemistry*; D010088:Oxidoreductases / Q000737:chemistry*; D011106:Polyisoprenyl Phosphates / Q000737:chemistry; D011485:Protein Binding; D021281:Quantitative Structure-Activity Relationship
D004164:Diphosphonates; D045782:Hemiterpenes; D008024:Ligands; D009097:Multienzyme Complexes; D063065:Organophosphonates; D009943:Organophosphorus Compounds; D011106:Polyisoprenyl Phosphates; D010088:Oxidoreductases; C114231:1-deoxy-D-xylulose 5-phosphate reductoisomerase; D019883:Alkyl and Aryl Transferases; D051228:Geranyltranstransferase; D019747:Aldose-Ketose Isomerases; D019748:Carbon-Carbon Double Bond Isomerases; C021453:isopentenyldiphosphate delta-isomerase