The microglia-activating potential of thrombin: the protease is not involved in the induction of proinflammatory cytokines and chemokines.
Hanisch
Uwe-Karsten
UK
Department of Cellular Neurosciences, Max Delbrück Center for Molecular Medicine, D-13092 Berlin, Germany. ukhanisch@med.uni-goettingen.de
van Rossum
Denise
D
Xie
Yiheng
Y
Gast
Klaus
K
Misselwitz
Rolf
R
Auriola
Seppo
S
Goldsteins
Gundars
G
Koistinaho
Jari
J
Kettenmann
Helmut
H
Möller
Thomas
T
D000595:Amino Acid Sequence; D000818:Animals; D002417:Cattle; D002478:Cells, Cultured; D018925:Chemokines / Q000096:biosynthesis; D016207:Cytokines / Q000096:biosynthesis; D006801:Humans; D018836:Inflammation Mediators / Q000378:metabolism; D007700:Kinetics; D051379:Mice; D017628:Microglia / Q000187:drug effects* / Q000502:physiology*; D008969:Molecular Sequence Data; D008970:Molecular Weight; D044462:Receptors, Proteinase-Activated / Q000187:drug effects / Q000502:physiology; D013917:Thrombin / Q000235:genetics / Q000302:isolation & purification / Q000494:pharmacology* / Q000502:physiology
D018925:Chemokines; D016207:Cytokines; D018836:Inflammation Mediators; D044462:Receptors, Proteinase-Activated; D013917:Thrombin