title: Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts.
authors.affiliation: Department of Genetics, The University of Melbourne, Victoria, Australia.
authors.forename: Shayne A
authors.initials: SA
authors.lastname: Bellingham
authors.forename: Giuseppe D
authors.initials: GD
authors.lastname: Ciccotosto
authors.forename: B Elise
authors.initials: BE
authors.lastname: Needham
authors.forename: Lisa R
authors.initials: LR
authors.lastname: Fodero
authors.forename: Anthony R
authors.initials: AR
authors.lastname: White
authors.forename: Colin L
authors.initials: CL
authors.lastname: Masters
authors.forename: Roberto
authors.initials: R
authors.lastname: Cappai
authors.forename: James
authors.initials: J
authors.lastname: Camakaris
mesh_terms: D016564:Amyloid beta-Protein Precursor / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D000818:Animals; D002478:Cells, Cultured; D002540:Cerebral Cortex / Q000166:cytology / Q000196:embryology; D003300:Copper / Q000378:metabolism*; D003301:Copper Radioisotopes; D004195:Disease Models, Animal; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism*; D015870:Gene Expression; D006706:Homeostasis / Q000235:genetics; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D009474:Neurons / Q000166:cytology / Q000378:metabolism*
chemical_list: D016564:Amyloid beta-Protein Precursor; C492952:Aplp2 protein, mouse; D003301:Copper Radioisotopes; D003300:Copper