Genetically increasing Myoc expression supports a necessary pathologic role of abnormal proteins in glaucoma.
Gould
Douglas B
DB
The Jackson Laboratory, Bar Harbor, Maine, USA.
Miceli-Libby
Laura
L
Savinova
Olga V
OV
Torrado
Mario
M
Tomarev
Stanislav I
SI
Smith
Richard S
RS
John
Simon W M
SW
D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000494:pharmacology; D000328:Adult; D000818:Animals; D003598:Cytoskeletal Proteins; D005123:Eye / Q000033:anatomy & histology; D005136:Eye Proteins / Q000235:genetics* / Q000378:metabolism*; D005786:Gene Expression Regulation / Q000187:drug effects; D005902:Glaucoma, Open-Angle / Q000139:chemically induced / Q000235:genetics / Q000378:metabolism*; D006023:Glycoproteins / Q000235:genetics* / Q000378:metabolism*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects / Q000502:physiology*; D051379:Mice; D008810:Mice, Inbred C57BL; D008822:Mice, Transgenic; D009900:Optic Nerve / Q000033:anatomy & histology / Q000378:metabolism; D011401:Promoter Regions, Genetic; D012165:Retinal Ganglion Cells / Q000166:cytology / Q000378:metabolism; D014129:Trabecular Meshwork / Q000166:cytology / Q000378:metabolism; D000099179:Myocilin
D000305:Adrenal Cortex Hormones; D003598:Cytoskeletal Proteins; D005136:Eye Proteins; D006023:Glycoproteins; D000099179:Myocilin