Glycyrrhizin and related compounds down-regulate production of inflammatory chemokines IL-8 and eotaxin 1 in a human lung fibroblast cell line.
Matsui
Sachiko
S
International Department, Minophagen Pharmaceutical Co., Ltd., 8-10-22, Akasaka, Minato-ku, Tokyo 107-0052, Japan.
Matsumoto
Hiroatsu
H
Sonoda
Yoshiko
Y
Ando
Kumi
K
Aizu-Yokota
Eriko
E
Sato
Toshitsugu
T
Kasahara
Tadashi
T
D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D054413:Chemokine CCL11; D019742:Chemokines, CC / Q000037:antagonists & inhibitors* / Q000378:metabolism; D015536:Down-Regulation / Q000187:drug effects / Q000235:genetics* / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005333:Fetus; D005347:Fibroblasts / Q000378:metabolism / Q000473:pathology; D006034:Glycyrrhetinic Acid / Q000031:analogs & derivatives* / Q000276:immunology* / Q000494:pharmacology; D019695:Glycyrrhizic Acid / Q000276:immunology* / Q000494:pharmacology; D006801:Humans; D020128:Inhibitory Concentration 50; D016209:Interleukin-8 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D008168:Lung / Q000378:metabolism / Q000473:pathology; D015394:Molecular Structure; D009504:Neutrophils / Q000502:physiology; D009844:Oligosaccharides / Q000145:classification / Q000276:immunology / Q000494:pharmacology; D016133:Polymerase Chain Reaction / Q000379:methods; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D013329:Structure-Activity Relationship
C515456:CCL11 protein, human; D054413:Chemokine CCL11; D019742:Chemokines, CC; D016209:Interleukin-8; D009844:Oligosaccharides; D012333:RNA, Messenger; C482685:glycyrrhetic acid mono-glucuronide; D019695:Glycyrrhizic Acid; D006034:Glycyrrhetinic Acid