title: Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth.
authors.affiliation: California Institute of Technology, Division of Biology, Pasadena, CA 91125, USA.
authors.forename: Wange
authors.initials: W
authors.lastname: Lu
authors.forename: Vicky
authors.initials: V
authors.lastname: Yamamoto
authors.forename: Blanca
authors.initials: B
authors.lastname: Ortega
authors.forename: David
authors.initials: D
authors.lastname: Baltimore
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D002454:Cell Differentiation / Q000235:genetics*; D002460:Cell Line; D002490:Central Nervous System / Q000166:cytology / Q000196:embryology* / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D000072261:Dishevelled Proteins; D029721:Drosophila Proteins; D004622:Embryo, Mammalian / Q000166:cytology / Q000196:embryology* / Q000378:metabolism; D051157:Frizzled Receptors; D005809:Genes, Regulator / Q000235:genetics; D020439:Growth Cones / Q000378:metabolism* / Q000648:ultrastructure; D006801:Humans; D051821:Lymphoid Enhancer-Binding Factor 1; D046911:Macromolecular Substances; D051379:Mice; D008822:Mice, Transgenic; D010750:Phosphoproteins; D011485:Protein Binding / Q000235:genetics; D017434:Protein Structure, Tertiary / Q000235:genetics; D011506:Proteins / Q000235:genetics / Q000378:metabolism; D011518:Proto-Oncogene Proteins / Q000235:genetics / Q000378:metabolism*; D034741:RNA, Small Interfering; D020794:Receptor Protein-Tyrosine Kinases / Q000235:genetics / Q000378:metabolism*; D043562:Receptors, G-Protein-Coupled; D017981:Receptors, Neurotransmitter / Q000235:genetics / Q000378:metabolism; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism; D051153:Wnt Proteins; D051155:Wnt1 Protein; D060508:Wnt3 Protein; D060509:Wnt3A Protein
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D004268:DNA-Binding Proteins; D000072261:Dishevelled Proteins; D029721:Drosophila Proteins; D051157:Frizzled Receptors; C489739:Fzd1 protein, mouse; D051821:Lymphoid Enhancer-Binding Factor 1; D046911:Macromolecular Substances; D010750:Phosphoproteins; D011506:Proteins; D011518:Proto-Oncogene Proteins; D034741:RNA, Small Interfering; D043562:Receptors, G-Protein-Coupled; D017981:Receptors, Neurotransmitter; D014157:Transcription Factors; C495247:WNT1 protein, human; C555510:WNT3A protein, human; D051153:Wnt Proteins; D051155:Wnt1 Protein; C495246:Wnt1 protein, mouse; D060508:Wnt3 Protein; D060509:Wnt3A Protein; C555511:Wnt3a protein, mouse; C000606588:dsh protein, Drosophila; D020794:Receptor Protein-Tyrosine Kinases; C118148:Ryk protein, mouse