Inhibition of 5-lipoxygenase induces cell death in anti-inflammatory fatty acid-treated HL-60 cells.
Gillis
Robert C
RC
Division of Trauma and Critical Care, Department of Surgery, Graduate School of Medicine, The University of Tennessee Medical Center, Knoxville, Tennessee 37920, USA.
Daley
Brian J
BJ
Enderson
Blaine L
BL
Karlstad
Michael D
MD
D017209:Apoptosis / Q000187:drug effects*; D001094:Arachidonate 5-Lipoxygenase / Q000378:metabolism; D002470:Cell Survival / Q000187:drug effects; D016861:Cyclooxygenase Inhibitors; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D015118:Eicosapentaenoic Acid / Q000494:pharmacology*; D004750:Enteral Nutrition; D005434:Flow Cytometry; D018922:HL-60 Cells; D006801:Humans; D016859:Lipoxygenase Inhibitors; D017965:gamma-Linolenic Acid / Q000494:pharmacology*
D016861:Cyclooxygenase Inhibitors; D004338:Drug Combinations; D016859:Lipoxygenase Inhibitors; D017965:gamma-Linolenic Acid; D015118:Eicosapentaenoic Acid; D001094:Arachidonate 5-Lipoxygenase