Structure/function analyses of human serum paraoxonase (HuPON1) mutants designed from a DFPase-like homology model.
Yeung
David T
DT
Biochemical Pharmacology Branch, Pharmacology Division, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010-5400, USA.
Josse
Denis
D
Nicholson
James D
JD
Khanal
Akhil
A
McAndrew
Christopher W
CW
Bahnson
Brian J
BJ
Lenz
David E
DE
Cerasoli
Douglas M
DM
D000818:Animals; D043303:Aryldialkylphosphatase / Q000097:blood / Q000737:chemistry* / Q000235:genetics*; D001483:Base Sequence; D020134:Catalytic Domain / Q000235:genetics; D002942:Circular Dichroism; D004247:DNA / Q000235:genetics; D049832:Decapodiformes / Q000201:enzymology; D006801:Humans; D066298:In Vitro Techniques; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D044345:Phosphoric Triester Hydrolases / Q000737:chemistry; D011487:Protein Conformation; D017433:Protein Structure, Secondary; D011994:Recombinant Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism
D011994:Recombinant Proteins; D004247:DNA; D044345:Phosphoric Triester Hydrolases; D043303:Aryldialkylphosphatase; C468406:PON1 protein, human; C020061:diisopropyl-fluorophosphatase