In vivo and in vitro chondrotoxicity of ciprofloxacin in juvenile rats.
Li
Ping
P
Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 200032, China.
Cheng
Neng-Neng
NN
Chen
Bin-Yan
BY
Wang
Yong-Ming
YM
D000818:Animals; D000890:Anti-Infective Agents / Q000493:pharmacokinetics / Q000633:toxicity*; D019540:Area Under Curve; D002358:Cartilage, Articular / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D049109:Cell Proliferation / Q000187:drug effects; D002478:Cells, Cultured; D019902:Chondrocytes / Q000166:cytology* / Q000378:metabolism; D002939:Ciprofloxacin / Q000493:pharmacokinetics / Q000633:toxicity*; D008297:Male; D011509:Proteoglycans / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley
D000890:Anti-Infective Agents; D011509:Proteoglycans; D002939:Ciprofloxacin