A mixture of isothiocyanates induces cyclin B1- and p53-mediated cell-cycle arrest and apoptosis of human T lymphoblastoid cells.
Fimognari
C
C
Department of Pharmacology, University of Bologna, via Irnerio 48, 40126, Italy. carmela.fimognari@unibo.it
Nüsse
M
M
Berti
F
F
Iori
R
R
Cantelli-Forti
G
G
Hrelia
P
P
D017209:Apoptosis / Q000502:physiology*; D002453:Cell Cycle / Q000502:physiology*; D002851:Chromatography, High Pressure Liquid; D019926:Cyclin B / Q000502:physiology*; D056744:Cyclin B1; D005434:Flow Cytometry; D005961:Glucosinolates / Q000494:pharmacology; D006801:Humans; D017879:Isothiocyanates / Q000494:pharmacology*; D019169:Jurkat Cells; D011518:Proto-Oncogene Proteins / Q000378:metabolism; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism / Q000502:physiology*; D051028:bcl-2-Associated X Protein
C494826:BAX protein, human; C534699:CCNB1 protein, human; D019926:Cyclin B; D056744:Cyclin B1; D005961:Glucosinolates; D017879:Isothiocyanates; D011518:Proto-Oncogene Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D016159:Tumor Suppressor Protein p53; D051028:bcl-2-Associated X Protein