Spinal dorsal horn calcium channel alpha2delta-1 subunit upregulation contributes to peripheral nerve injury-induced tactile allodynia.
Li
Chun-Ying
CY
Department of Anesthesiology, College of Medicine, University of California, Irvine, Irvine, California 92717, USA.
Song
Yan-Hua
YH
Higuera
Emiliano S
ES
Luo
Z David
ZD
D000818:Animals; D015153:Blotting, Western; D015220:Calcium Channels / Q000096:biosynthesis / Q000502:physiology*; D020746:Calcium Channels, L-Type; D005727:Ganglia, Spinal / Q000378:metabolism; D006941:Hyperesthesia / Q000503:physiopathology*; D008026:Ligation; D008297:Male; D009437:Neuralgia / Q000503:physiopathology; D009474:Neurons / Q000378:metabolism; D020319:Oligodeoxyribonucleotides, Antisense; D010146:Pain / Q000503:physiopathology*; D010523:Peripheral Nervous System Diseases / Q000503:physiopathology*; D017729:Presynaptic Terminals / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D013116:Spinal Cord / Q000378:metabolism / Q000503:physiopathology*; D013126:Spinal Nerve Roots / Q000502:physiology; D013127:Spinal Nerves / Q000502:physiology; D014110:Touch; D015854:Up-Regulation
C486060:Cacna2d1 protein, rat; D015220:Calcium Channels; D020746:Calcium Channels, L-Type; D020319:Oligodeoxyribonucleotides, Antisense