A cutaneous gene therapy approach to treat infection through keratinocyte-targeted overexpression of antimicrobial peptides.
Carretero
Marta
M
Epithelial Damage, Repair, and Tissue Engineering, Ciemat-Fundación Marcelino Botín, Madrid, Spain.
Del Río
Marcela
M
García
Marta
M
Escámez
María José
MJ
Mirones
Isabel
I
Rivas
Luis
L
Balague
Cristina
C
Jorcano
Jose Luis
JL
Larcher
Fernando
F
D000256:Adenoviridae / Q000235:genetics; D000900:Anti-Bacterial Agents / Q000096:biosynthesis; D023181:Antimicrobial Cationic Peptides / Q000096:biosynthesis / Q000235:genetics*; D002460:Cell Line; D015870:Gene Expression; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors; D006801:Humans; D066298:In Vitro Techniques; D015603:Keratinocytes / Q000378:metabolism*; D012867:Skin / Q000033:anatomy & histology / Q000382:microbiology; D017192:Skin Diseases, Bacterial / Q000628:therapy*; D014161:Transduction, Genetic
D000900:Anti-Bacterial Agents; D023181:Antimicrobial Cationic Peptides