Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice.
Lin
Jiandie
J
Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
Wu
Pei-Hsuan
PH
Tarr
Paul T
PT
Lindenberg
Katrin S
KS
St-Pierre
Julie
J
Zhang
Chen-Yu
CY
Mootha
Vamsi K
VK
Jäger
Sibylle
S
Vianna
Claudia R
CR
Reznick
Richard M
RM
Cui
Libin
L
Manieri
Monia
M
Donovan
Mi X
MX
Wu
Zhidan
Z
Cooper
Marcus P
MP
Fan
Melina C
MC
Rohas
Lindsay M
LM
Zavacki
Ann Marie
AM
Cinti
Saverio
S
Shulman
Gerald I
GI
Lowell
Bradford B
BB
Krainc
Dimitri
D
Spiegelman
Bruce M
BM
D000222:Adaptation, Physiological / Q000235:genetics; D000818:Animals; D001069:Appetite Regulation / Q000235:genetics; D001480:Basal Ganglia Diseases / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D001921:Brain / Q000378:metabolism* / Q000503:physiopathology; D022782:CCAAT-Enhancer-Binding Protein-beta / Q000235:genetics / Q000378:metabolism; D003342:Corpus Striatum / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D004734:Energy Metabolism / Q000235:genetics*; D005786:Gene Expression Regulation / Q000235:genetics; D005943:Gluconeogenesis / Q000235:genetics*; D005947:Glucose / Q000378:metabolism; D022781:Hepatocytes / Q000378:metabolism; D006706:Homeostasis / Q000235:genetics; D006948:Hyperkinesis / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology; D008099:Liver / Q000378:metabolism / Q000503:physiopathology; D051379:Mice; D018345:Mice, Knockout; D008928:Mitochondria / Q000235:genetics / Q000378:metabolism*; D019636:Neurodegenerative Diseases / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D009474:Neurons / Q000378:metabolism; D009765:Obesity / Q000235:genetics / Q000378:metabolism; D000071248:Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; D015534:Trans-Activators / Q000172:deficiency / Q000235:genetics*; D014157:Transcription Factors; D015854:Up-Regulation / Q000235:genetics
D022782:CCAAT-Enhancer-Binding Protein-beta; D000071248:Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; C485290:Ppargc1a protein, mouse; D015534:Trans-Activators; D014157:Transcription Factors; D005947:Glucose