title: One site mutation disrupts dimer formation in human DPP-IV proteins.
authors.affiliation: Division of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Taipei 115, Taiwan, Republic of China.
authors.forename: Chia-Hui
authors.initials: CH
authors.lastname: Chien
authors.forename: Li-Hao
authors.initials: LH
authors.lastname: Huang
authors.forename: Chi-Yuan
authors.initials: CY
authors.lastname: Chou
authors.forename: Yuan-Shou
authors.initials: YS
authors.lastname: Chen
authors.forename: Yu-San
authors.initials: YS
authors.lastname: Han
authors.forename: Gu-Gang
authors.initials: GG
authors.lastname: Chang
authors.forename: Po-Huang
authors.initials: PH
authors.lastname: Liang
authors.forename: Xin
authors.initials: X
authors.lastname: Chen
mesh_terms: D000243:Adenosine Deaminase / Q000737:chemistry* / Q000235:genetics* / Q000378:metabolism; D058892:Adenosine Deaminase Inhibitors; D000595:Amino Acid Sequence; D000818:Animals; D016367:Baculoviridae / Q000235:genetics; D001483:Base Sequence; D002460:Cell Line; D017124:Conserved Sequence; D018076:DNA, Complementary / Q000235:genetics; D019281:Dimerization; D018819:Dipeptidyl Peptidase 4 / Q000737:chemistry* / Q000235:genetics* / Q000378:metabolism; D006023:Glycoproteins / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D020836:Protein Structure, Quaternary; D011994:Recombinant Proteins / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D012492:Salts; D017386:Sequence Homology, Amino Acid
chemical_list: D058892:Adenosine Deaminase Inhibitors; D018076:DNA, Complementary; D006023:Glycoproteins; D011994:Recombinant Proteins; D012492:Salts; C042807:DPP4 protein, human; D018819:Dipeptidyl Peptidase 4; D000243:Adenosine Deaminase