Brain serotonin transporter availability predicts treatment response to selective serotonin reuptake inhibitors.
Kugaya
Akira
A
Department of Psychiatry, Yale University, New Haven, Connecticut, USA. akira.kugaya@yale.edu
Sanacora
Gerard
G
Staley
Julie K
JK
Malison
Robert T
RT
Bozkurt
Ali
A
Khan
Shaukat
S
Anand
Amit
A
Van Dyck
Christopher H
CH
Baldwin
Ronald M
RM
Seibyl
John P
JP
Charney
Dennis
D
Innis
Robert B
RB
D000328:Adult; D000704:Analysis of Variance; D001931:Brain Mapping; D003042:Cocaine / Q000031:analogs & derivatives* / Q000378:metabolism; D003865:Major Depressive Disorder / Q000188:drug therapy* / Q000378:metabolism; D004027:Diencephalon / Q000000981:diagnostic imaging / Q000187:drug effects / Q000378:metabolism*; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use; D006801:Humans; D007457:Iodine Radioisotopes / Q000378:metabolism; D008297:Male; D016555:Matched-Pair Analysis; D008562:Membrane Glycoproteins / Q000378:metabolism*; D026901:Membrane Transport Proteins / Q000378:metabolism*; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D017374:Paroxetine / Q000627:therapeutic use; D019275:Radiopharmaceuticals / Q000378:metabolism; D012016:Reference Values; D012701:Serotonin / Q000378:metabolism; D050486:Serotonin Plasma Membrane Transport Proteins; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D015899:Tomography, Emission-Computed, Single-Photon; D016896:Treatment Outcome
D003042:Cocaine; D005473:Fluoxetine; D007457:Iodine Radioisotopes; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; D017374:Paroxetine; D019275:Radiopharmaceuticals; D012701:Serotonin; D050486:Serotonin Plasma Membrane Transport Proteins; D017367:Selective Serotonin Reuptake Inhibitors; C493230:SLC6A4 protein, human; C069723:2beta-carbomethoxy-3beta-(4-iodophenyl)tropane