title: HCV NS5B polymerase-bound conformation of a soluble sulfonamide inhibitor by 2D transferred NOESY.
authors.affiliation: ViroChem Pharma Inc., 275 Armand-Frappier Blvd., Laval, Quebec, Canada H7V 4A7. cyannopoulos@virochempharma.com
authors.forename: Constantin G
authors.initials: CG
authors.lastname: Yannopoulos
authors.forename: Ping
authors.initials: P
authors.lastname: Xu
authors.forename: Feng
authors.initials: F
authors.lastname: Ni
authors.forename: Laval
authors.initials: L
authors.lastname: Chan
authors.forename: Oswy Z
authors.initials: OZ
authors.lastname: Pereira
authors.forename: T Jagadeeswar
authors.initials: TJ
authors.lastname: Reddy
authors.forename: Sanjoy K
authors.initials: SK
authors.lastname: Das
authors.forename: Carl
authors.initials: C
authors.lastname: Poisson
authors.forename: Nghe
authors.initials: N
authors.lastname: Nguyen-Ba
authors.forename: Nathalie
authors.initials: N
authors.lastname: Turcotte
authors.forename: Melanie
authors.initials: M
authors.lastname: Proulx
authors.forename: Lilianne
authors.initials: L
authors.lastname: Halab
authors.forename: Wuyi
authors.initials: W
authors.lastname: Wang
authors.forename: Jean
authors.initials: J
authors.lastname: Bédard
authors.forename: Nicolas
authors.initials: N
authors.lastname: Morin
authors.forename: Martine
authors.initials: M
authors.lastname: Hamel
authors.forename: Olivier
authors.initials: O
authors.lastname: Nicolas
authors.forename: Darius
authors.initials: D
authors.lastname: Bilimoria
authors.forename: Lucille
authors.initials: L
authors.lastname: L'Heureux
authors.forename: Richard
authors.initials: R
authors.lastname: Bethell
authors.forename: Gervais
authors.initials: G
authors.lastname: Dionne
mesh_terms: D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000737:chemistry; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D011725:Pyridines / Q000737:chemistry; D012324:RNA-Dependent RNA Polymerase / Q000037:antagonists & inhibitors* / Q000737:chemistry; D013329:Structure-Activity Relationship; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry; D013876:Thiophenes / Q000737:chemistry; D017361:Viral Nonstructural Proteins / Q000037:antagonists & inhibitors* / Q000737:chemistry
chemical_list: D000998:Antiviral Agents; D011725:Pyridines; D013449:Sulfonamides; D013876:Thiophenes; D017361:Viral Nonstructural Proteins; C087036:NS-5 protein, hepatitis C virus; D012324:RNA-Dependent RNA Polymerase