In vitro cytotoxic and genotoxic effects of diphenylarsinic acid, a degradation product of chemical warfare agents.
Ochi
Takafumi
T
Laboratory of Toxicology, Faculty of Pharmaceutical Sciences, Teikyo University, Sagamiko, Kanagawa 199-0195, Japan. tkfmochi@pharm.teikyo-u.ac.jp
Suzuki
Toshihide
T
Isono
Hideo
H
Kaise
Toshikazu
T
D000818:Animals; D001152:Arsenicals; D045744:Cell Line, Tumor; D002470:Cell Survival; D002478:Cells, Cultured; D018385:Centrosome / Q000187:drug effects / Q000648:ultrastructure; D002619:Chemical Warfare Agents / Q000633:toxicity*; D002875:Chromosomes / Q000187:drug effects / Q000648:ultrastructure; D006224:Cricetinae; D004247:DNA / Q000096:biosynthesis; D005455:Fluorescent Antibody Technique; D005978:Glutathione / Q000378:metabolism; D006801:Humans; D008297:Male; D008870:Microtubules / Q000187:drug effects / Q000648:ultrastructure; D008940:Mitotic Index; D009153:Mutagens; D008941:Spindle Apparatus / Q000187:drug effects / Q000648:ultrastructure; D013438:Sulfhydryl Compounds / Q000633:toxicity; D014404:Tubulin / Q000378:metabolism
D001152:Arsenicals; D002619:Chemical Warfare Agents; D009153:Mutagens; D013438:Sulfhydryl Compounds; D014404:Tubulin; D004247:DNA; D005978:Glutathione; C493087:diphenylarsinic acid