title: Muscarinic toxin 7 selectivity is dictated by extracellular receptor loops.
authors.affiliation: A. I. Virtanen Institute for Molecular Sciences, Department of Neurobiology, Kuopio University, FIN-70211 Kuopio, Finland.
authors.forename: Anu
authors.initials: A
authors.lastname: Kukkonen
authors.forename: Mikael
authors.initials: M
authors.lastname: Peräkylä
authors.forename: Karl E O
authors.initials: KE
authors.lastname: Akerman
authors.forename: Johnny
authors.initials: J
authors.lastname: Näsman
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D002118:Calcium / Q000737:chemistry; D002460:Cell Line; D004305:Dose-Response Relationship, Drug; D004546:Elapid Venoms / Q000737:chemistry* / Q000235:genetics* / Q000378:metabolism; D018698:Glutamic Acid / Q000737:chemistry; D006801:Humans; D007313:Insecta; D007700:Kinetics; D008024:Ligands; D008239:Lysine / Q000737:chemistry; D008969:Molecular Sequence Data; D016296:Mutagenesis; D016297:Mutagenesis, Site-Directed; D009154:Mutation; D010649:Phenylalanine / Q000737:chemistry; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D043643:Receptor, Muscarinic M1 / Q000737:chemistry; D043587:Receptor, Muscarinic M3 / Q000737:chemistry; D011994:Recombinant Proteins / Q000737:chemistry; D017386:Sequence Homology, Amino Acid; D013997:Time Factors
chemical_list: D004546:Elapid Venoms; D008024:Ligands; D043643:Receptor, Muscarinic M1; D043587:Receptor, Muscarinic M3; D011994:Recombinant Proteins; C419876:muscarinic toxin 7; D018698:Glutamic Acid; D010649:Phenylalanine; D008239:Lysine; D002118:Calcium