title: A novel constitutively active mutation in the second cytoplasmic loop of metabotropic glutamate receptor.
authors.affiliation: Department of Biophysics, Graduate School of Science, Kyoto University and Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Corporation, Kyoto, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Yamashita
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Kai
authors.forename: Akihisa
authors.initials: A
authors.lastname: Terakita
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Shichida
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites / Q000502:physiology; D002460:Cell Line; D019206:GTP-Binding Protein alpha Subunits, Gi-Go / Q000378:metabolism; D043802:GTP-Binding Protein alpha Subunits, Gq-G11 / Q000378:metabolism; D006801:Humans; D008024:Ligands; D051379:Mice; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D017433:Protein Structure, Secondary / Q000502:physiology; D017434:Protein Structure, Tertiary / Q000235:genetics / Q000502:physiology; D018094:Receptors, Metabotropic Glutamate / Q000235:genetics* / Q000378:metabolism*; D013329:Structure-Activity Relationship
chemical_list: D008024:Ligands; D018094:Receptors, Metabotropic Glutamate; C111435:metabotropic glutamate receptor 8; C104077:metabotropic glutamate receptor type 1; D019206:GTP-Binding Protein alpha Subunits, Gi-Go; D043802:GTP-Binding Protein alpha Subunits, Gq-G11