title: Metabolic engineering of isoprenoid biosynthesis in Arabidopsis for the production of taxadiene, the first committed precursor of Taxol.
authors.affiliation: Departament de Bioquímica i Biologia Molecular, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1-7, 08028 Barcelona, Spain.
authors.forename: Oscar
authors.initials: O
authors.lastname: Besumbes
authors.forename: Susanna
authors.initials: S
authors.lastname: Sauret-Güeto
authors.forename: Michael A
authors.initials: MA
authors.lastname: Phillips
authors.forename: Santiago
authors.initials: S
authors.lastname: Imperial
authors.forename: Manuel
authors.initials: M
authors.lastname: Rodríguez-Concepción
authors.forename: Albert
authors.initials: A
authors.lastname: Boronat
mesh_terms: D000475:Alkenes / Q000378:metabolism*; D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism*; D004224:Diterpenes / Q000378:metabolism*; D005786:Gene Expression Regulation / Q000235:genetics; D007535:Isomerases / Q000235:genetics / Q000378:metabolism*; D017239:Paclitaxel / Q000096:biosynthesis*; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D030821:Plants, Genetically Modified; D011106:Polyisoprenyl Phosphates / Q000378:metabolism*; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism; D020946:Taxus / Q000201:enzymology / Q000235:genetics*
chemical_list: D000475:Alkenes; D004224:Diterpenes; D010940:Plant Proteins; D011106:Polyisoprenyl Phosphates; D011994:Recombinant Proteins; C093125:taxa-4(5),11(12)diene; D007535:Isomerases; C095926:taxa-4(5),11(12)-diene synthase; C002963:geranylgeranyl pyrophosphate; D017239:Paclitaxel