title: Impact of E1a modifications on tumor-selective adenoviral replication and toxicity.
authors.affiliation: Division of Pulmonary & Critical Care Medicine, New York University School of Medicine, New York, NY 10016, USA.
authors.forename: Harald
authors.initials: H
authors.lastname: Sauthoff
authors.forename: Teona
authors.initials: T
authors.lastname: Pipiya
authors.forename: Sheila
authors.initials: S
authors.lastname: Heitner
authors.forename: Shu
authors.initials: S
authors.lastname: Chen
authors.forename: Bertram
authors.initials: B
authors.lastname: Bleck
authors.forename: Joan
authors.initials: J
authors.lastname: Reibman
authors.forename: William
authors.initials: W
authors.lastname: Chang
authors.forename: Robert G
authors.initials: RG
authors.lastname: Norman
authors.forename: William N
authors.initials: WN
authors.lastname: Rom
authors.forename: John G
authors.initials: JG
authors.lastname: Hay
mesh_terms: D000256:Adenoviridae / Q000235:genetics*; D017500:Adenovirus E1A Proteins / Q000235:genetics* / Q000378:metabolism; D020816:Amino Acid Motifs / Q000235:genetics; D001665:Binding Sites / Q000235:genetics; D045744:Cell Line, Tumor; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors / Q000633:toxicity*; D006801:Humans; D047468:Immunoprecipitation; D009369:Neoplasms / Q000628:therapy*; D009687:Nuclear Proteins / Q000378:metabolism; D017434:Protein Structure, Tertiary / Q000235:genetics; D016160:Retinoblastoma Protein / Q000235:genetics / Q000378:metabolism; D016196:S Phase; D017384:Sequence Deletion; D015534:Trans-Activators / Q000378:metabolism; D014779:Virus Replication / Q000235:genetics*
chemical_list: D017500:Adenovirus E1A Proteins; D009687:Nuclear Proteins; D016160:Retinoblastoma Protein; D015534:Trans-Activators