title: Mutational status of IgVH genes consistent with antigen-driven selection but not percent of mutations has prognostic impact in B-cell chronic lymphocytic leukemia.
authors.affiliation: Clinical and Experimental Hematology Research Unit, Centro di Riferimento Oncologico, I.R.C.C.S., Aviano, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Degan
authors.forename: Maurizio
authors.initials: M
authors.lastname: Rupolo
authors.forename: Michele Dal
authors.initials: MD
authors.lastname: Bo
authors.forename: Anna
authors.initials: A
authors.lastname: Stefanon
authors.forename: Riccardo
authors.initials: R
authors.lastname: Bomben
authors.forename: Antonella
authors.initials: A
authors.lastname: Zucchetto
authors.forename: Enrica
authors.initials: E
authors.lastname: Canton
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Berretta
authors.forename: Paola
authors.initials: P
authors.lastname: Nanni
authors.forename: Agostino
authors.initials: A
authors.lastname: Steffan
authors.forename: Pier Ferruccio
authors.initials: PF
authors.lastname: Ballerini
authors.forename: Daniela
authors.initials: D
authors.lastname: Damiani
authors.forename: Carlo
authors.initials: C
authors.lastname: Pucillo
authors.forename: Vincenza
authors.initials: V
authors.lastname: Attadia
authors.forename: Alfonso
authors.initials: A
authors.lastname: Colombatti
authors.forename: Valter
authors.initials: V
authors.lastname: Gattei
mesh_terms: D036541:ADP-ribosyl Cyclase / Q000235:genetics; D051997:ADP-ribosyl Cyclase 1; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000941:Antigens / Q000737:chemistry; D015703:Antigens, CD / Q000235:genetics; D002454:Cell Differentiation; D004252:DNA Mutational Analysis; D005260:Female; D005803:Genes, Immunoglobulin / Q000235:genetics*; D006801:Humans; D007135:Immunoglobulin Variable Region / Q000235:genetics*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000235:genetics*; D008297:Male; D008562:Membrane Glycoproteins; D008875:Middle Aged; D009154:Mutation; D011379:Prognosis; D013997:Time Factors
chemical_list: D000941:Antigens; D015703:Antigens, CD; D007135:Immunoglobulin Variable Region; D008562:Membrane Glycoproteins; D036541:ADP-ribosyl Cyclase; C498154:CD38 protein, human; D051997:ADP-ribosyl Cyclase 1