Human mAChR antibodies from Sjögren syndrome sera increase cerebral nitric oxide synthase activity and nitric oxide synthase mRNA level.
Reina
Silvia
S
Pharmacology Unit, School of Dentistry, University of Buenos Aires, 1121AAH, Argentina.
Sterin-Borda
Leonor
L
Orman
Betina
B
Borda
Enri
E
D000328:Adult; D000818:Animals; D001323:Autoantibodies / Q000097:blood*; D002478:Cells, Cultured; D002540:Cerebral Cortex / Q000378:metabolism*; D004789:Enzyme Activation; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007527:Isoenzymes / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D019001:Nitric Oxide Synthase / Q000378:metabolism*; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000032:analysis; D051381:Rats; D017208:Rats, Wistar; D011976:Receptors, Muscarinic / Q000276:immunology*; D012859:Sjogren's Syndrome / Q000097:blood* / Q000276:immunology
D001323:Autoantibodies; D007074:Immunoglobulin G; D007527:Isoenzymes; D012333:RNA, Messenger; D011976:Receptors, Muscarinic; D019001:Nitric Oxide Synthase