Apoptotic topoisomerase I-DNA complexes induced by staurosporine-mediated oxygen radicals.
Sordet
Olivier
O
Laboratory of Molecular Pharmacology, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, Maryland 20892-4255, USA.
Khan
Qasim A
QA
Plo
Isabelle
I
Pourquier
Philippe
P
Urasaki
Yoshimasa
Y
Yoshida
Akira
A
Antony
Smitha
S
Kohlhagen
Glenda
G
Solary
Eric
E
Saparbaev
Murat
M
Laval
Jacques
J
Pommier
Yves
Y
D017209:Apoptosis / Q000187:drug effects / Q000502:physiology*; D004247:DNA / Q000187:drug effects / Q000378:metabolism*; D053938:DNA Fragmentation / Q000187:drug effects; D004264:DNA Topoisomerases, Type I / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D017382:Reactive Oxygen Species / Q000378:metabolism*; D019311:Staurosporine / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
D004791:Enzyme Inhibitors; D017382:Reactive Oxygen Species; D004247:DNA; D004264:DNA Topoisomerases, Type I; D019311:Staurosporine