Novel histone deacetylase inhibitors: cyclic tetrapeptide with trifluoromethyl and pentafluoroethyl ketones.
Jose
Binoy
B
CREST Research Project, Japan Science and Technology Agency, Saitama 332-0012, Japan.
Oniki
Yusuke
Y
Kato
Tamaki
T
Nishino
Norikazu
N
Sumida
Yuko
Y
Yoshida
Minoru
M
D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001665:Binding Sites; D002851:Chromatography, High Pressure Liquid; D004355:Drug Stability; D056572:Histone Deacetylase Inhibitors; D006655:Histone Deacetylases / Q000737:chemistry*; D006801:Humans; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D010456:Peptides, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011401:Promoter Regions, Genetic; D016283:Proto-Oncogene Proteins p21(ras) / Q000235:genetics; D013329:Structure-Activity Relationship; D015032:Zinc / Q000737:chemistry
D000970:Antineoplastic Agents; D056572:Histone Deacetylase Inhibitors; D007659:Ketones; D010456:Peptides, Cyclic; D006655:Histone Deacetylases; C501009:HRAS protein, human; D016283:Proto-Oncogene Proteins p21(ras); D015032:Zinc