Calmodulin-myosin light chain kinase inhibition changes fibroblast-populated collagen lattice contraction, cell migration, focal adhesion formation, and wound contraction.
Levinson
Howard
H
Division of Plastic Surgery, MS Hershey Medical Center, Hershey, PA, USA. hlev1@yahoo.com
Moyer
Kurtis E
KE
Saggers
Gregory C
GC
Ehrlich
H Paul
HP
D000818:Animals; D002147:Calmodulin / Q000037:antagonists & inhibitors; D002448:Cell Adhesion / Q000187:drug effects / Q000502:physiology; D002465:Cell Movement / Q000187:drug effects / Q000502:physiology; D002478:Cells, Cultured; D004195:Disease Models, Animal; D005260:Female; D005347:Fibroblasts / Q000187:drug effects* / Q000502:physiology; D005476:Fluphenazine / Q000494:pharmacology*; D007150:Immunohistochemistry; D008297:Male; D009219:Myosin-Light-Chain Kinase / Q000187:drug effects / Q000378:metabolism* / Q000502:physiology; D010766:Phosphorylation; D011336:Probability; D051381:Rats; D017207:Rats, Sprague-Dawley; D012680:Sensitivity and Specificity; D013449:Sulfonamides / Q000494:pharmacology*; D014945:Wound Healing / Q000187:drug effects / Q000502:physiology; D014947:Wounds and Injuries / Q000188:drug therapy* / Q000201:enzymology*
D002147:Calmodulin; D013449:Sulfonamides; C017967:W 7; D009219:Myosin-Light-Chain Kinase; D005476:Fluphenazine