Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain.
Chen
Jingshan
J
Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA.
Lipska
Barbara K
BK
Halim
Nader
N
Ma
Quang D
QD
Matsumoto
Mitsuyuki
M
Melhem
Samer
S
Kolachana
Bhaskar S
BS
Hyde
Thomas M
TM
Herman
Mary M
MM
Apud
Jose
J
Egan
Michael F
MF
Kleinman
Joel E
JE
Weinberger
Daniel R
DR
D000704:Analysis of Variance; D000818:Animals; D015153:Blotting, Western; D002394:Catechol O-Methyltransferase / Q000235:genetics*; D017931:DNA Primers; D015971:Gene Expression Regulation, Enzymologic / Q000502:physiology*; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D008214:Lymphocytes / Q000201:enzymology; D008745:Methylation; D051379:Mice; D016297:Mutagenesis, Site-Directed; D020641:Polymorphism, Single Nucleotide; D017397:Prefrontal Cortex / Q000201:enzymology* / Q000473:pathology; D011506:Proteins / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012737:Sex Factors
D017931:DNA Primers; D011506:Proteins; D012333:RNA, Messenger; D002394:Catechol O-Methyltransferase