title: Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination.
authors.affiliation: Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Antony
authors.forename: Guido
authors.initials: G
authors.lastname: van Marle
authors.forename: Wycliffe
authors.initials: W
authors.lastname: Opii
authors.forename: D Allan
authors.initials: DA
authors.lastname: Butterfield
authors.forename: François
authors.initials: F
authors.lastname: Mallet
authors.forename: Voon Wee
authors.initials: VW
authors.lastname: Yong
authors.forename: John L
authors.initials: JL
authors.lastname: Wallace
authors.forename: Robert M
authors.initials: RM
authors.lastname: Deacon
authors.forename: Kenneth
authors.initials: K
authors.lastname: Warren
authors.forename: Christopher
authors.initials: C
authors.lastname: Power
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology / Q000627:therapeutic use; D001253:Astrocytes / Q000276:immunology* / Q000378:metabolism / Q000821:virology; D016923:Cell Death / Q000276:immunology; D002460:Cell Line; D003373:Coumaric Acids / Q000494:pharmacology / Q000627:therapeutic use; D004195:Disease Models, Animal; D004660:Encephalitis / Q000188:drug therapy / Q000276:immunology* / Q000821:virology; D020077:Endogenous Retroviruses / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D015686:Gene Products, env / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D051379:Mice; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000188:drug therapy / Q000276:immunology* / Q000821:virology; D009186:Myelin Sheath / Q000378:metabolism; D009836:Oligodendroglia / Q000276:immunology* / Q000378:metabolism; D010084:Oxidation-Reduction; D011257:Pregnancy Proteins / Q000235:genetics / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism; D051381:Rats; D017382:Reactive Oxygen Species / Q000037:antagonists & inhibitors / Q000378:metabolism; D011993:Recombinant Fusion Proteins / Q000494:pharmacology
chemical_list: D000975:Antioxidants; D003373:Coumaric Acids; D015686:Gene Products, env; D011257:Pregnancy Proteins; D012333:RNA, Messenger; D017382:Reactive Oxygen Species; D011993:Recombinant Fusion Proteins; C405335:syncytin; C004999:ferulic acid