title: Apoptotic topoisomerase I-DNA complexes induced by staurosporine-mediated oxygen radicals.
authors.affiliation: Laboratory of Molecular Pharmacology, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, Maryland 20892-4255, USA.
authors.forename: Olivier
authors.initials: O
authors.lastname: Sordet
authors.forename: Qasim A
authors.initials: QA
authors.lastname: Khan
authors.forename: Isabelle
authors.initials: I
authors.lastname: Plo
authors.forename: Philippe
authors.initials: P
authors.lastname: Pourquier
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Urasaki
authors.forename: Akira
authors.initials: A
authors.lastname: Yoshida
authors.forename: Smitha
authors.initials: S
authors.lastname: Antony
authors.forename: Glenda
authors.initials: G
authors.lastname: Kohlhagen
authors.forename: Eric
authors.initials: E
authors.lastname: Solary
authors.forename: Murat
authors.initials: M
authors.lastname: Saparbaev
authors.forename: Jacques
authors.initials: J
authors.lastname: Laval
authors.forename: Yves
authors.initials: Y
authors.lastname: Pommier
mesh_terms: D017209:Apoptosis / Q000187:drug effects / Q000502:physiology*; D004247:DNA / Q000187:drug effects / Q000378:metabolism*; D053938:DNA Fragmentation / Q000187:drug effects; D004264:DNA Topoisomerases, Type I / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D017382:Reactive Oxygen Species / Q000378:metabolism*; D019311:Staurosporine / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
chemical_list: D004791:Enzyme Inhibitors; D017382:Reactive Oxygen Species; D004247:DNA; D004264:DNA Topoisomerases, Type I; D019311:Staurosporine