Effect of cyclooxygenase-1 inhibition in postoperative pain is developmentally regulated.
Ririe
Douglas G
DG
Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1009, USA. dririe@wfubmc.edu
Prout
Heather M
HM
Eisenach
James C
JC
D000367:Age Factors; D000818:Animals; D051545:Cyclooxygenase 1; D016861:Cyclooxygenase Inhibitors / Q000627:therapeutic use*; D007527:Isoenzymes / Q000032:analysis / Q000037:antagonists & inhibitors*; D008297:Male; D008565:Membrane Proteins; D017288:Pain Threshold / Q000187:drug effects; D010149:Postoperative Pain / Q000188:drug therapy* / Q000503:physiopathology; D011451:Prostaglandin-Endoperoxide Synthases / Q000032:analysis; D011720:Pyrazoles / Q000627:therapeutic use*; D051381:Rats; D017207:Rats, Sprague-Dawley
D016861:Cyclooxygenase Inhibitors; D007527:Isoenzymes; D008565:Membrane Proteins; D011720:Pyrazoles; C115461:SC 560; D051545:Cyclooxygenase 1; D011451:Prostaglandin-Endoperoxide Synthases; C496513:Ptgs1 protein, rat