Three new compounds from the plant Lippia alva as inhibitors of chemokine receptor 5 (CCR5).
Hegde
Vinod R
VR
Schering Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA. vinod.hegde@spcorp.com
Pu
Haiyan
H
Patel
Mahesh
M
Das
Pradip R
PR
Strizki
Julie
J
Gullo
Vincent P
VP
Chou
Chuan-Chu
CC
Buevich
Alexei V
AV
Chan
Tze-Ming
TM
D019380:Anti-HIV Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D065100:CCR5 Receptor Antagonists; D020013:Calcium Signaling; D045744:Cell Line, Tumor; D003521:Cyclopropanes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D032411:Lippia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000737:chemistry; D013329:Structure-Activity Relationship
D019380:Anti-HIV Agents; D065100:CCR5 Receptor Antagonists; D003521:Cyclopropanes; D007783:Lactones; D010936:Plant Extracts