Prostratin induces HIV activation and downregulates HIV receptors in peripheral blood lymphocytes.
Rullas
Joaquín
J
AIDS Immunopathogenesis Unit, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Madrid, Spain.
Bermejo
Mercedes
M
García-Pérez
Javier
J
Beltán
Manuela
M
González
Nuria
N
Hezareh
Marjan
M
Brown
Stephen J
SJ
Alcamí
José
J
D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D015536:Down-Regulation; D006678:HIV / Q000187:drug effects* / Q000235:genetics / Q000502:physiology; D016325:HIV Long Terminal Repeat; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000187:drug effects* / Q000378:metabolism / Q000821:virology; D016328:NF-kappa B / Q000378:metabolism; D010703:Phorbol Esters / Q000494:pharmacology*; D019713:Receptors, CCR5 / Q000378:metabolism; D019718:Receptors, CXCR4 / Q000378:metabolism; D015728:Receptors, HIV / Q000187:drug effects* / Q000378:metabolism; D013997:Time Factors; D015533:Transcriptional Activation; D014162:Transfection; D014775:Virus Activation
D016328:NF-kappa B; D010703:Phorbol Esters; D019713:Receptors, CCR5; D019718:Receptors, CXCR4; D015728:Receptors, HIV; C070999:prostratin