Transgenic analysis reveals that thyroid hormone receptor is sufficient to mediate the thyroid hormone signal in frog metamorphosis.
Buchholz
Daniel R
DR
Section on Molecular Morphogenesis, Laboratory of Gene Regulation and Development, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, 20892, USA.
Tomita
Akihiro
A
Fu
Liezhen
L
Paul
Bindu D
BD
Shi
Yun-Bo
YB
D000818:Animals; D030801:Animals, Genetically Modified; D018507:Gene Expression Regulation, Developmental; D007814:Larva / Q000033:anatomy & histology / Q000502:physiology; D008675:Metamorphosis, Biological / Q000502:physiology*; D009024:Morphogenesis / Q000502:physiology; D009865:Oocytes / Q000502:physiology; D011401:Promoter Regions, Genetic; D011988:Receptors, Thyroid Hormone / Q000235:genetics / Q000378:metabolism*; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism; D012097:Repressor Proteins / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology*; D014158:Transcription, Genetic; D015533:Transcriptional Activation; D019076:Transgenes; D014284:Triiodothyronine / Q000235:genetics / Q000378:metabolism*; D029867:Xenopus Proteins / Q000235:genetics / Q000378:metabolism; D014982:Xenopus laevis / Q000033:anatomy & histology / Q000502:physiology
D011988:Receptors, Thyroid Hormone; D011993:Recombinant Fusion Proteins; D012097:Repressor Proteins; D029867:Xenopus Proteins; C470195:nuclear receptor corepressor, Xenopus; D014284:Triiodothyronine