U1 RNA induces innate immunity signaling.
Hoffman
Robert W
RW
University of Miami and the Miami VA Medical Center, Miami, Florida 33136, USA.
Gazitt
Tal
T
Foecking
Mark F
MF
Ortmann
Robert A
RA
Misfeldt
Michael
M
Jorgenson
Rebecca
R
Young
Steven L
SL
Greidinger
Eric L
EL
D000818:Animals; D002455:Cell Division / Q000276:immunology; D002460:Cell Line; D006801:Humans; D007113:Immunity, Innate / Q000276:immunology*; D015850:Interleukin-6 / Q000096:biosynthesis / Q000276:immunology; D016209:Interleukin-8 / Q000096:biosynthesis / Q000276:immunology; D008024:Ligands; D008562:Membrane Glycoproteins / Q000276:immunology*; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D012342:RNA, Small Nuclear / Q000276:immunology*; D011956:Receptors, Cell Surface / Q000276:immunology*; D017412:Ribonucleoprotein, U1 Small Nuclear / Q000276:immunology; D015398:Signal Transduction / Q000276:immunology*; D051196:Toll-Like Receptor 3; D051198:Toll-Like Receptor 5; D051193:Toll-Like Receptors
D015850:Interleukin-6; D016209:Interleukin-8; D008024:Ligands; D008562:Membrane Glycoproteins; D012342:RNA, Small Nuclear; D011956:Receptors, Cell Surface; D017412:Ribonucleoprotein, U1 Small Nuclear; C495344:TLR3 protein, human; C495346:TLR5 protein, human; D051196:Toll-Like Receptor 3; D051198:Toll-Like Receptor 5; D051193:Toll-Like Receptors; C405483:U1 small nuclear RNA