Silencing of the retinoid response gene TIG1 by promoter hypermethylation in nasopharyngeal carcinoma.
Kwong
Joseph
J
Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China.
Lo
Kwok-Wai
KW
Chow
Lillian Shuk-Nga
LS
Chan
Franky Leung
FL
To
Ka-Fai
KF
Huang
Dolly P
DP
D000818:Animals; D001374:Azacitidine / Q000031:analogs & derivatives* / Q000494:pharmacology; D002478:Cells, Cultured; D019175:DNA Methylation; D015254:DNA Modification Methylases / Q000037:antagonists & inhibitors; D000077209:Decitabine; D004791:Enzyme Inhibitors / Q000494:pharmacology; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects; D020868:Gene Silencing; D006801:Humans; D056892:Mediator Complex; D051379:Mice; D009303:Nasopharyngeal Neoplasms / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D009305:Nasopharynx / Q000378:metabolism / Q000473:pathology; D011401:Promoter Regions, Genetic / Q000235:genetics*; D018168:Receptors, Retinoic Acid / Q000235:genetics; D012176:Retinoids / Q000494:pharmacology*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014157:Transcription Factors / Q000235:genetics*; D014183:Transplantation, Heterologous
D004791:Enzyme Inhibitors; C416944:MED15 protein, human; D056892:Mediator Complex; C437968:PLAAT4 protein, human; D018168:Receptors, Retinoic Acid; D012176:Retinoids; D014157:Transcription Factors; D000077209:Decitabine; D015254:DNA Modification Methylases; D001374:Azacitidine