Bisphosphonate-ciprofloxacin bound to Skelite is a prototype for enhancing experimental local antibiotic delivery to injured bone.
Buxton
T B
TB
Department of Clinical Investigation, Dwight David Eisenhower Army Medical Center, Fort Gordon, Georgia 30905, USA. Thomas.Buxton@SE.AMEDD.Army.mil
Walsh
D S
DS
Harvey
S B
SB
McPherson
J C
JC
Hartmann
J F
JF
Plowman
K M
KM
D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D002130:Calcium Phosphates; D002939:Ciprofloxacin / Q000008:administration & dosage*; D004164:Diphosphonates / Q000008:administration & dosage*; D004337:Drug Carriers; D004338:Drug Combinations; D010019:Osteomyelitis / Q000188:drug therapy*; D051381:Rats; D013203:Staphylococcal Infections / Q000188:drug therapy; D013211:Staphylococcus aureus; D013530:Surgical Wound Infection / Q000188:drug therapy*; D013978:Tibial Fractures
D000890:Anti-Infective Agents; D002130:Calcium Phosphates; D004164:Diphosphonates; D004337:Drug Carriers; D004338:Drug Combinations; D002939:Ciprofloxacin; C020243:calcium phosphate