Elevation in urinary levels of pyridinium cross-links of collagen following chymopapain-induced degradation of articular cartilage in the rabbit knee provides evidence of metabolic changes in bone.
Uebelhart
D
D
Department of Biochemistry, Rush Medical College at Rush-Presbyterian-St Luke's Medical Center, Chicago, IL 60612, USA.
Thonar
E J
EJ
Pietryla
D W
DW
Williams
J M
JM
D000375:Aging / Q000652:urine; D000596:Amino Acids / Q000652:urine*; D000818:Animals; D001169:Arthritis, Experimental / Q000139:chemically induced / Q000473:pathology / Q000652:urine*; D002358:Cartilage, Articular / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D002917:Chymopapain; D003094:Collagen / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D008297:Male; D011817:Rabbits
D000596:Amino Acids; C015484:pyridinoline; C036020:deoxypyridinoline; D003094:Collagen; D002917:Chymopapain