Low autocrine interferon beta production as a gene therapy approach for AIDS: Infusion of interferon beta-engineered lymphocytes in macaques chronically infected with SIVmac251.
Gay
Wilfried
W
CEA, Laboratoire d'Immuno-Pathologie Expérimentale, Service de Neurovirologie, CRSSA, EPHE, IPSC, Université Paris XI, 18 route du Panorama 92265 Fontenay aux Roses, Cedex, France. WGAYLEN@aol.com
Lauret
Evelyne
E
Boson
Bertrand
B
Larghero
Jérome
J
Matheux
Franck
F
Peyramaure
Sophie
S
Rousseau
Véronique
V
Dormont
Dominique
D
De Maeyer
Edward
E
Le Grand
Roger
R
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D000818:Animals; D001483:Base Sequence; D018791:CD4 Lymphocyte Count; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology; D017931:DNA Primers; D004279:DNA, Viral / Q000235:genetics / Q000302:isolation & purification; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors; D016899:Interferon-beta / Q000008:administration & dosage / Q000235:genetics* / Q000627:therapeutic use*; D017710:Lymphocyte Transfusion; D008214:Lymphocytes / Q000276:immunology*; D008252:Macaca fascicularis; D008297:Male; D011401:Promoter Regions, Genetic; D012367:RNA, Viral / Q000097:blood / Q000235:genetics / Q000302:isolation & purification; D012190:Retroviridae; D017384:Sequence Deletion; D016097:Simian Acquired Immunodeficiency Syndrome / Q000188:drug therapy* / Q000276:immunology; D015302:Simian Immunodeficiency Virus / Q000235:genetics / Q000276:immunology*; D019562:Viral Load
D017931:DNA Primers; D004279:DNA, Viral; D012367:RNA, Viral; D016899:Interferon-beta