title: Investigation of efflux transport of dehydroepiandrosterone sulfate and mitoxantrone at the mouse blood-brain barrier: a minor role of breast cancer resistance protein.
authors.affiliation: Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
authors.forename: Young-Joo
authors.initials: YJ
authors.lastname: Lee
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kusuhara
authors.forename: Johan W
authors.initials: JW
authors.lastname: Jonker
authors.forename: Alfred H
authors.initials: AH
authors.lastname: Schinkel
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Sugiyama
mesh_terms: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000378:metabolism; D000070997:ATP Binding Cassette Transporter, Subfamily G, Member 2; D018528:ATP-Binding Cassette Transporters / Q000235:genetics / Q000378:metabolism*; D000166:Acridines / Q000494:pharmacology; D000818:Animals; D015703:Antigens, CD / Q000378:metabolism; D000970:Antineoplastic Agents / Q000493:pharmacokinetics; D001692:Biological Transport; D001812:Blood-Brain Barrier / Q000378:metabolism*; D019314:Dehydroepiandrosterone Sulfate / Q000493:pharmacokinetics*; D004347:Drug Interactions; D008562:Membrane Glycoproteins / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D008942:Mitoxantrone / Q000493:pharmacokinetics*; D044005:Tetrahydroisoquinolines / Q000494:pharmacology; D060245:Tetraspanin 29; D014316:Tritium
chemical_list: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000070997:ATP Binding Cassette Transporter, Subfamily G, Member 2; D018528:ATP-Binding Cassette Transporters; C501412:Abcg2 protein, mouse; D000166:Acridines; D015703:Antigens, CD; D000970:Antineoplastic Agents; C554869:CD9 protein, human; C554870:Cd9 protein, mouse; D008562:Membrane Glycoproteins; D044005:Tetrahydroisoquinolines; D060245:Tetraspanin 29; D014316:Tritium; D019314:Dehydroepiandrosterone Sulfate; D008942:Mitoxantrone; C083501:Elacridar