CYP 17 and CYP 19 inhibitors. Evaluation of fluorine effects on the inhibiting activity of regioselectively fluorinated 1-(Naphthalen-2-ylmethyl)imidazoles.
Hartmann
Rolf W
RW
8.5 Pharmaceutical and Medicinal Chemistry, Saarland University, P.O. Box 151150, D-66041 Saarbrücken, Germany. rwh@mx.uni-saarland.de
Palusczak
Anja
A
Lacan
Fabrice
F
Ricci
Giacomo
G
Ruzziconi
Renzo
R
D001141:Aromatase / Q000378:metabolism*; D047072:Aromatase Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology*; D005461:Fluorine / Q000494:pharmacology*; D007093:Imidazoles / Q000494:pharmacology*; D007700:Kinetics; D015394:Molecular Structure; D009281:Naphthalenes / Q000494:pharmacology*; D013254:Steroid 17-alpha-Hydroxylase / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship
D047072:Aromatase Inhibitors; D007093:Imidazoles; D009281:Naphthalenes; D005461:Fluorine; D001141:Aromatase; D013254:Steroid 17-alpha-Hydroxylase