Essential issues of laboratory investigation for patients with haemophilia and bleeding disorders.
Apart from history-taking and physical examination, laboratory investigation is one of the essential issues for the definite diagnosis of haemophilia and bleeding disorders. The limited resources of medical personnel, equipment and reagents should be shared among several departments in the hospital, especially for serving patients with common genetic diseases such as thalassemia and haemoglobinopathies. Medical personnel require appropriate training to expand their skills in laboratory techniques. Laboratory procedures can be created, modified and simplified using locally produced and shared equipment. Molecular genetic studies can also be set up at different levels of hospital service using simple, rapid and low-cost methods. Finally, a system of periodic external quality control will guarantee the accuracy of laboratory results.
Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand. raajs@mahidol.ac.th
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Chuansumrit
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McCraw
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Preston
D001778:Blood Coagulation Disorders / Q000175:diagnosis*; D002624:Chemistry, Clinical / Q000193:education / Q000379:methods; D019411:Clinical Laboratory Techniques; D006467:Hemophilia A / Q000175:diagnosis*; D006801:Humans; D011361:Professional Competence; D011786:Quality Control