Candiduria in hospital patients: a study prospective.
The presence of Candida species in the urine is frequent among hospitalized patients. We studied sample urine of 205 hospitalized patients during a 1-year period to determine the incidence of nosocomial candiduria. The yeasts were isolated in 22% (45/205) urine cultures and risk factors in these patients were analyzed. Candida albicans was isolated in 35.6% and C. tropicalis (22%) was the second most frequent species isolated. Most patients were women (57.8%) with a mean age of 48.7 years. The principal risk factors that were observed in patients with candiduria included antibiotics therapy (100%), urinary catheterization (84.4%), surgical procedure (66.7%), female sex and extended hospitalization. The efficacy of fluconazole therapy to eradicate Candida from urine was demonstrated (p =0.05). Of the 23 individuals who received antifungal therapy, candiduria persisted in 9 (39.2%) and of 22 patients who received no antifungal therapy, the candiduria persisted in 15 (68.2%).
Instituto de Patologia Tropical e Saúde Pública da Universidade Federal de Goiás; Brazil.
Cláudia Castelo Branco Artiaga
CC
Kobayashi
Orionalda Fátima Lisboa
OF
de Fernandes
Karla Carvalho
KC
Miranda
Efigênia Dantas
ED
de Sousa
Maria do Rosário Rodrigues
Mdo R
Silva
D000935:Antifungal Agents / Q000627:therapeutic use*; D002175:Candida / Q000302:isolation & purification*; D002177:Candidiasis / Q000188:drug therapy / Q000382:microbiology / Q000652:urine*; D015169:Colony Count, Microbial; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology / Q000652:urine*; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D014556:Urine / Q000382:microbiology
D000935:Antifungal Agents; D015725:Fluconazole