The effect of lens edge design versus anterior capsule overlap on posterior capsule opacification.
OBJECTIVE
To determine whether lens edge design or anterior capsule overlap on the intraocular lens (IOL) has greater effect on posterior capsule opacification (PCO).


METHODS
Retrospective cohort clinical study.


METHODS
Retrospective.


METHODS
Academic clinical practice.


METHODS
The patient population consisted of 259 uncomplicated surgical patients (259 eyes) with no confounding comorbidity and at least 1 year of follow-up after surgical placement of a silicone or hydrophobic acrylic lens.


METHODS
Digital retroilluminated photographs were taken to ascertain PCO, anterior capsular opacification (ACO), previous neodymium:YAG capsulotomy and degree of anterior capsule overlap on the IOL optic.


METHODS
PCO, ACO, YAG capsulotomy rate, and anterior capsule overlap on the IOL optic.


RESULTS
One hundred forty-eight digital images (74 silicone and 74 acrylic) were measurable for both anterior capsule overlap and PCO. Complete 360 degrees of anterior capsule overlap on the IOL was associated with decreased PCO (P = <.001). A significant negative correlation was found between the degree of anterior capsule overlap and PCO (P = <.001). Evaluation of PCO, and YAG capsulotomy rates were similar between acrylic and silicone lenses. Minimal anterior capsule overlap may also be associated with PCO prevention.


CONCLUSIONS
Implanting a lens with complete anterior capsule overlap on the IOL was found to significantly reduce PCO, which advantage appeared to be greater than PCO prevention by a truncated, sharp edge IOL design.
Department of Ophthalmology and Visual Sciences, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.
Stacy R
SR
Smith
Todd
T
Daynes
Michael
M
Hinckley
Trevin R
TR
Wallin
Randall J
RJ
Olson
D000180:Acrylic Resins; D000368:Aged; D000869:Anterior Eye Segment; D002386:Cataract / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007903:Lens Capsule, Crystalline / Q000601:surgery*; D019654:Lens Implantation, Intraocular / Q000379:methods*; D007910:Lenses, Intraocular; D008297:Male; D011183:Postoperative Complications / Q000517:prevention & control*; D011474:Prosthesis Design; D012189:Retrospective Studies; D012826:Silicone Elastomers
D000180:Acrylic Resins; D012826:Silicone Elastomers