Antibiotic treatment for influenza does not affect resolution of illness, secondary visits or lost workdays.
Antibiotics are common prescribed against influenza, although no trials of their efficacy have been published. We compared clinical and societal outcomes in 701 patients (56% flu-positive) according to use of antibiotics. The median duration of illness, rate of secondary visits, and lost workdays did not differ between antibiotic and non-antibiotic treated patients. Antibiotics are unnecessary expenses in the initial treatment of influenza, as they can give potential side-effects and contribute to spread of antibiotic-resistant bacteria.
Institut National de la Santé Et de la Recherche Médicale, INSERM Unit 444, Université Pierre et Marie Curie, Assistance Publique- Hôpitaux de Paris, Paris, France.
Fabrice
F
Carrat
Michael
M
Schwarzinger
Bruno
B
Housset
Alain-Jacques
AJ
Valleron
D000041:Absenteeism; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D005602:France; D006801:Humans; D007251:Influenza, Human / Q000188:drug therapy* / Q000503:physiopathology; D008875:Middle Aged; D018582:Sick Leave / Q000706:statistics & numerical data*
D000900:Anti-Bacterial Agents