Molecular and physiological comparisons between Saccharomyces cerevisiae and Saccharomyces boulardii.
In this paper, comparative molecular studies between authentic Saccharomyces cerevisiae strains, related species, and the strain described as Saccharomyces boulardii were performed. The response of a S. boulardii strain and a S. cerevisiae strain (W303) to different stress conditions was also evaluated. The results obtained in this study show that S. boulardii is genetically very close or nearly identical to S. cerevisiae. Metabolically and physiologically, however, it shows a very different behavior, particularly in relation to growth yield and resistance to temperature and acidic stresses, which are important characteristics for a microorganism to be used as a probiotic.
Núcleo de pesquisa em Ciências Biológicas, Instituto de Ciências Exatas e Biológicas, Universidade Federal de Ouro Preto, Ouro Preto Minas Gerais, Brazil.
Juliana L R
JL
Fietto
Raquel S
RS
Araújo
Frederico N
FN
Valadão
Luciano G
LG
Fietto
Rogelio L
RL
Brandão
Maria J
MJ
Neves
Fátima C O
FC
Gomes
Jacques R
JR
Nicoli
Ieso M
IM
Castro
D004271:DNA, Fungal / Q000032:analysis; D021903:DNA, Ribosomal Spacer / Q000032:analysis; D018869:Heat-Shock Response; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008969:Molecular Sequence Data; D016533:Mycological Typing Techniques; D019936:Probiotics; D012440:Saccharomyces / Q000145:classification* / Q000235:genetics* / Q000254:growth & development / Q000502:physiology; D012441:Saccharomyces cerevisiae / Q000145:classification* / Q000235:genetics* / Q000254:growth & development / Q000502:physiology; D017422:Sequence Analysis, DNA; D013696:Temperature
D004271:DNA, Fungal; D021903:DNA, Ribosomal Spacer