Mutagenicity of CORAGRAF and REKAGRAF in the Ames test.
Mutagenicity of CORAGRAF (natural coral) and REKAGRAF (hydroxyapatite) was tested in Ames test with and without an external metabolic activation system (S9). The test revealed no mutagenic activity of both locally produced osseous substitutes.
School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
A H
AH
Suzina
A
A
Azlina
O
O
Shamsuria
A R
AR
Samsudin
D020137:Base Pair Mismatch / Q000187:drug effects; D001711:Biotransformation / Q000502:physiology; D018786:Bone Substitutes / Q000633:toxicity*; D002119:Calcium Carbonate / Q000633:toxicity*; D002869:Chromosome Aberrations; D004926:Escherichia coli / Q000235:genetics; D006801:Humans; D006882:Hydroxyapatites / Q000633:toxicity*; D008422:Materials Testing; D009152:Mutagenicity Tests; D012486:Salmonella typhimurium / Q000235:genetics
D018786:Bone Substitutes; D006882:Hydroxyapatites; D002119:Calcium Carbonate