Hepatitis C and B-cell lymphoma.
Hepatitis C virus (HCV) infection is a major public health problem worldwide. HCV, a lymphotropic and hepatotropic virus, is clearly associated with cirrhosis, end-stage liver disease, autoimmune phenomena, hepatocellular carcinoma, and essential mixed cryoglobulinemia. Recently, there have been increasing reports of B-cell lymphomas in patients with HCV infection, and epidemiologic data from several sources have demonstrated high rates of HCV seroprevalence in patients with B-cell malignancies. This review describes a case report of a patient with HCV and chronic lymphocytic leukemia, followed by a summary of the literature on this rapidly evolving area.
Division of Hematology and Oncology, New York Hospital-Cornell Medical Center, New York, New York 10021, USA.
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D005260:Female; D006526:Hepatitis C / Q000150:complications* / Q000453:epidemiology / Q000628:therapy; D006801:Humans; D016031:Liver Transplantation; D016393:Lymphoma, B-Cell / Q000821:virology*; D008875:Middle Aged