Psoriasis remission after laparoscopic Roux-en-Y gastric bypass for morbid obesity.
BACKGROUND
Psoriasis is a chronic skin disease characterized by epithelial hyperplasia and an accelerated rate of epithelial turnover affecting approximately 1-3% of the population. Exogenous and endogenous factors including morbid obesity can increase the morbidity of psoriasis.


METHODS
A 55-year-old male, who weighed 131 kg with BMI 41 kg/m2, underwent laparoscopic Roux-en-Y gastric bypass (LRYGBP). He had a 15-year duration of severe psoriasis and was being medically treated. At 12 months after LRYGBP, he had lost 39 kg (68% EWL), and had complete resolution of the psoriasis and had discontinued all preoperative medications related to the disease. At 2 years after LRYGBP, psoriasis has not recurred.


CONCLUSIONS
Weight loss after LRYGBP should be considered as a strategy in the treatment of severe psoriasis in morbidly obese patients.
The Bariatric Institute, Cleveland Clinic Florida, Weston, FL 33331, USA.
Guillermo
G
Higa-Sansone
Samuel
S
Szomstein
Flavia
F
Soto
Oscar
O
Brasecsco
Carlos
C
Cohen
Raul J
RJ
Rosenthal
D000713:Anastomosis, Roux-en-Y; D015390:Gastric Bypass / Q000379:methods*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications / Q000601:surgery*; D011565:Psoriasis / Q000150:complications / Q000628:therapy*; D012074:Remission Induction; D016896:Treatment Outcome; D015431:Weight Loss