Polycyclic aromatic hydrocarbons: physicochemical properties, environmental appearance and impact on living organisms.
Human exposure to environmental pollution is of great interest nowadays. Many substances present in the environment are considered as carcinogenic to humans. Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental carcinogens. In this paper, PAHs are described: their physicochemical properties, natural and anthropogenic sources, environmental, dietary and occupational exposure and impact on human health. Metabolical carcinogenic activation of PAHs and the role of metabolism products as biomarkers of PAH exposure have been discussed.
Skupińska
Katarzyna
K
Confocal Microscopy Laboratory, National Institute of Public Health, 30/34 Chełmska, 00-725 Warsaw, Poland.
Misiewicz
Irena
I
Kasprzycka-Guttman
Teresa
T
D002273:Carcinogens / Q000009:adverse effects* / Q000737:chemistry; D004781:Environmental Exposure / Q000009:adverse effects*; D006801:Humans; D011084:Polycyclic Aromatic Hydrocarbons / Q000009:adverse effects* / Q000737:chemistry; D013329:Structure-Activity Relationship
D002273:Carcinogens; D011084:Polycyclic Aromatic Hydrocarbons