Molecular networks in model systems.
Model organisms, especially the budding yeast, are leading systems in the transformation of biology into an information science. With the availability of genome sequences and genome-scale data generation technologies, the extraction of biological insight from complex integrated molecular networks has become a major area of research. Here I examine key concepts and review research developments. I propose specific areas of research effort to drive network analysis in directions that will promote modeling with increasing predictive power.
Galitski
Timothy
T
Institute for Systems Biology, Seattle, Washington 98103, USA. tgalitski@systemsbiology.org
D019295:Computational Biology; D008957:Models, Genetic