Postsplenectomy recurrence of thrombocytopenia with an accessory spleen.
Autoimmune thrombocytopenic purpura (AITP) is an autoimmune disorder that results from antiplatelet autoantibodies; these autoantibodies cause platelet destruction in the reticluoendothelial system. Oral corticosteroid therapy is the first line treatment. Splenectomy is the major treatment modality after the failure of more conservative medical therapy. Approximately 15% of the patients will relapse either soon after splenectomy or, as is less common, many years later. The presence of an accessory spleen should be sought. We experienced a patient with a known diagnosis of autoimmune thrombocytopenic purpura who had a worsening thrombocytopenia 11 years after splenectomy. This patient was diagnosed with an accessory spleen. Accessory splenectomy was performed with only a transient elevation of the platelets. We report here on this case with a review of the literature.
Woo
Jin Hyun
JH
Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Park
Sung Hyun
SH
Park
Yoon Kyung
YK
Choi
Chan Bum
CB
Choi
Yun Young
YY
Ahn
Myung Ju
MJ
Kim
In Soon
IS
D000328:Adult; D005260:Female; D006801:Humans; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000601:surgery*; D011877:Radionuclide Imaging; D012008:Recurrence; D013154:Spleen / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000601:surgery; D013156:Splenectomy