Susac's syndrome or catastrophic antiphospholipid syndrome?
Susac's syndrome is a microangiopathic disorder of unknown pathogenesis presenting with encephalopathy, hearing loss and branch retinal artery occlusions. The term 'catastrophic' antiphospholipid syndrome (APS) is used to define a subset of the APS characterized by thrombotic microangiopathy with clinical evidence of three or more organ involvement developed in a short period of time. We describe a patient with typical features of Susac's syndrome, that appeared in less than a week, in whom aPL were detected, thus fulfilling criteria for 'probable' catastrophic APS.
Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Catalonia, Spain.
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Bucciarelli
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Cervera
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M
Martínez
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X
Latorre
J
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Font
D000328:Adult; D016736:Antiphospholipid Syndrome / Q000175:diagnosis*; D001927:Brain Diseases / Q000175:diagnosis*; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis*; D006801:Humans; D015356:Retinal Artery Occlusion / Q000175:diagnosis*; D013577:Syndrome; D013927:Thrombosis / Q000175:diagnosis; D014652:Vascular Diseases / Q000175:diagnosis*