[Association of hereditary hemochromatosis and pernicious anaemia].
BACKGROUND
Hereditary hemochromatosis is inherited as an autosomal recessive trait. It is characterized by increased absorption of dietary iron. The association between pernicious anaemia and hereditary hemochromatosis has never been described.


METHODS
We report a case of paradoxical association of hereditary hemochromatosis and pernicious anaemia.


CONCLUSIONS
It seems that pernicious anaemia may prevent manifestations of hemochromatosis. We suppose that this protective role is due to atrophic body gastritis with iron malabsorption.
Service de médecine interne, CHR Pellegrin, place Raba-Léon, 33000 Bordeaux, France. hassene.attout@chu-bordeaux.fr
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Sériès
D000368:Aged; D000752:Anemia, Pernicious / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D001815:Bloodletting; D005293:Ferritins / Q000097:blood; D005500:Follow-Up Studies; D006432:Hemochromatosis / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D006801:Humans; D008297:Male; D009154:Mutation; D013997:Time Factors; D014168:Transferrin / Q000032:analysis; D016896:Treatment Outcome; D014805:Vitamin B 12 / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use
D014168:Transferrin; D005293:Ferritins; D014805:Vitamin B 12