Infantile acute hemorrhagic edema and rotavirus infection.
Infantile acute hemorrhagic edema (AHE) is a benign condition characterized by a dramatic onset of inflammatory edema and ecchymotic purpura in a target or cockade pattern. It is considered an uncommon form of cutaneous vasculitis occurring in children younger than 2 years of age. The outbreak is frequently preceded by an immunization or various infections. We describe an 11-month-old girl with rosette-shaped purpuric plaques on the face and limbs, clinically consistent with a diagnosis of AHE of the skin, associated with fever and diarrhea. Laboratory investigations showed a rotavirus infection, which has not previously been reported in association with AHE of the skin. The disease had a benign course without relapses. Appropriate microbiologic investigations are advisable to confirm the possible etiologic role of rotavirus.
Operative Unit of Dermatology, 1st Medical Department, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy. vito.dilernia@asmn.re.it
Vito
V
Di Lernia
Mara
M
Lombardi
Giovanni
G
Lo Scocco
D003937:Diagnosis, Differential; D004431:Ear, External; D004487:Edema / Q000209:etiology*; D005121:Extremities; D005145:Face; D005260:Female; D006801:Humans; D007223:Infant; D011693:Purpura / Q000209:etiology*; D012400:Rotavirus Infections / Q000150:complications / Q000175:diagnosis* / Q000473:pathology