[New fluoroquinolones in urology].
The authors review the practice of using fluoroquinolones (FQ) of the second generation in urology: levofloxacine, sparfloxacine, moxifloxacine. Details are given on chemical structure of FQ, their antimicrobial spectrum, indications for FQ administration, pharmacokinetics, efficacy in complicated infections of the urinary tracts. Treatment with new FQ demonstrated a good effect: high clinical and bacteriological responses (100 and 98.5%; 88.7 and 78.1%, 95.7 and 85.7% in the treatment with levofloxacine, sparfloxacine, moxifloxacine, respectively). The area of clinical application of FQ is urinary infection, urogenital infections, sexually transmitted diseases.
I I
II
Derevianko
L A
LA
Hefedova
D000890:Anti-Infective Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects; D024841:Fluoroquinolones / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
D000890:Anti-Infective Agents; D024841:Fluoroquinolones