The involvement of hemozoin toxicity in depression of cellular immunity.
Human monocyte-derived macrophages are severely impaired after ingestion of isolated malaria pigment (hemozoin) or hemozoin-containing red blood cells'. In this brief review, Franco Turrini, Evelin Schwarzer and Poolo Arese discuss possible pothophysiologicol consequences, outline unresolved problems and provide an outlook for future research.
Department of Genetics Biology and Medical Chemistry, University of Torino Medical School, Torino, Italy.
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