[Levels of sex hormones in obese women with hypertension during various periods of reproductive activity].
OBJECTIVE
To assess effects of hypertension and obesity on blood plasma levels of sex hormones and gonadotropins in fertile and postmenopausal women.


METHODS
We assessed endocrinological status and measured levels of sex hormones and gonadotropins in 228 women with grade I-III hypertension (WHO, 1999) and 114 normotensive women of fertile and postmenopausal ages (17 to 74 years). There was a definite relationship between obesity and levels of sex hormones which did not depend on blood pressure level. The authors regarded this relationship as an endocrinological consequence of obesity. Severity of hypertension was associated with elevation of luteinizing and follicle-stimulating hormones and lowering of progesterone level in fertile women and with elevated levels of sex hormones in blood plasma in menopausal women. The authors interpreted the latter phenomenon as a sign of adrenal gland hyperfunction.
O A
OA
Baĭkova
V A
VA
Liusov
E M
EM
Evsikov
A A
AA
Oshnokova
A A
AA
Magomedova
D000293:Adolescent; D000308:Adrenocortical Hyperfunction / Q000097:blood / Q000503:physiopathology; D000328:Adult; D000367:Age Factors; D000368:Aged; D003627:Data Interpretation, Statistical; D004958:Estradiol / Q000097:blood; D004964:Estriol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000503:physiopathology; D007986:Luteinizing Hormone / Q000097:blood; D008593:Menopause; D008875:Middle Aged; D009765:Obesity / Q000097:blood* / Q000503:physiopathology; D017698:Postmenopause; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood; D013739:Testosterone / Q000097:blood
D012739:Gonadal Steroid Hormones; D013739:Testosterone; D011374:Progesterone; D004958:Estradiol; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D004964:Estriol