Antioxidant vitamin status in high exposure to oxidative stress in competitive athletes.
We conducted a cross-sectional study in 118 well-trained athletes to investigate 'high exposure' to sub-deficient antioxidant status, and consequently to oxidative damage, in relation to estimated daily energy expenditure (EE) and dietary antioxidant intake. Subjects completed 7 d food and activity records. Blood samples were obtained on day 8. Of the athletes 81, 60 and 43% had intakes of vitamins E, C and beta-carotene below two-thirds of the French RDA respectively, which is adjusted for EE (FRDAa). The deficit in vitamin E intake was positively correlated with EE (r 0.51, P<0.0001). All the athletes had normal plasma vitamins E and C and 14% had marginal plasma beta-carotene. Plasma thiobarbituric acid-reactive substances (TBARS) did not increase with increased EE. As evidenced by ANOVA, EE-induced vitamin C intakes increased and consequently led to increased plasma ascorbic acid concentrations. In male athletes, plasma total carotenoids were negatively correlated with plasma TBARS concentrations (r -0.31, P<0.006). The relationship between vitamin C intakes and plasma concentrations was logarithmic (r 0.59, P< 0.0001). To summarize, it is not clear whether vitamin E requirements are overestimated with reference to EE in the FRDAa. Daily requirements for vitamin C do not exceed 200 mg. Our present results could be interpreted as meaning that carotenoids play a protective role as exogenous antioxidants. Carotenoid intakes in athletes must be considered carefully.
Laboratoire Nutrition, Vieillissement et Maladies Cardio-vasculaires, Université Joseph Fourier, Domaine de la Merci, La Tronche, France.
Anne-Sophie
AS
Rousseau
Isabelle
I
Hininger
Stéphane
S
Palazzetti
Henri
H
Faure
Anne-Marie
AM
Roussel
Irène
I
Margaritis
D000328:Adult; D000975:Antioxidants / Q000008:administration & dosage* / Q000032:analysis; D001205:Ascorbic Acid / Q000008:administration & dosage / Q000097:blood; D003430:Cross-Sectional Studies; D004032:Diet; D005260:Female; D006801:Humans; D008297:Male; D018384:Oxidative Stress / Q000502:physiology*; D013177:Sports / Q000502:physiology*; D017392:Thiobarbituric Acid Reactive Substances / Q000032:analysis; D014810:Vitamin E / Q000008:administration & dosage / Q000097:blood; D014815:Vitamins / Q000008:administration & dosage* / Q000097:blood*; D024502:alpha-Tocopherol / Q000097:blood; D019207:beta Carotene / Q000097:blood
D000975:Antioxidants; D017392:Thiobarbituric Acid Reactive Substances; D014815:Vitamins; D019207:beta Carotene; D014810:Vitamin E; D024502:alpha-Tocopherol; D001205:Ascorbic Acid