Performance of the Binax NOW Streptococcus pneumoniae urinary antigen assay for diagnosis of pneumonia in children with underlying pulmonary diseases in the absence of acute pneumococcal infection.
The performance of the Binax NOW immunochromatographic test for detecting Streptococcus pneumoniae antigen in urine specimens from 103 children presenting underlying pulmonary diseases with no recent pneumococcal infection was assessed. Our data indicate that this assay is unlikely to be useful for discriminating between children with and without pneumococcal pneumonia.
Navarro
David
D
Department of Microbiology, University Clinical Hospital, Valencia, Spain.
García-Maset
Leonor
L
Gimeno
Concepción
C
Escribano
Amparo
A
García-de-Lomas
Juan
J
D000293:Adolescent; D000942:Antigens, Bacterial / Q000652:urine*; D002648:Child; D002675:Child, Preschool; D002845:Chromatography; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000379:methods; D007223:Infant; D008171:Lung Diseases / Q000150:complications*; D008297:Male; D011008:Pneumococcal Infections / Q000382:microbiology; D011018:Pneumonia, Pneumococcal / Q000175:diagnosis* / Q000382:microbiology; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity; D013296:Streptococcus pneumoniae / Q000302:isolation & purification*
D000942:Antigens, Bacterial; D011933:Reagent Kits, Diagnostic