Effects of ultraviolet B irradiation on cutaneous leishmaniasis.
Protection against many infectious diseases is mediated by cellular immunity in the competent host. Ultraviolet (UV) radiation, a component of sunlight, is a potent suppressor of cell-mediated immune responses. Suzanne Holmes Giannini discusses the possible relevance of ambient levels of UVB to pathogenesis and immunity in infectious diseases, with special reference to cutaneous leishmaniasis.
University of Maryland School of Medicine, Department of Microbiology and Immunology, 655 West Baltimore Street, Baltimore, MD 21201, USA.
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Giannini