Chronotherapy of malaria: an approach to malaria chemotherapy.
Chronotherapy is the science of the timing of drug application so as to achieve optimal therapeutic success for the treatment of disease. Here, Irene Landau, Alain Chabaud, Gilles Cambie and Hagai Ginsburg show how a suitable animal model can be chosen, how the stage of parasite development most susceptible to the drug can be identified, and how this can eventually be used for the improvement of drug treatment.
Laboratoire de Zoologie-Vers, associé ou CNRS, Museum National d'Histoire Naturelle, 61 rue Buffon, 75231 Paris Cedex 05, France.
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Chabaud
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Cambie
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Ginsburg