[Structural basis of alpha-tocopherol succinate as an antineoplastic agent].
Alpha-tocopherol succinate is a redox-silent analog of alpha-tocopherol which is the major component of vitamin E. Recently, the research findings showed that, as a kind of pro-vitamin E, alpha-tocopherol succinate possesses antineoplastic activity which alpha-tocopherol lacks of. In this review paper, the link between the structure and antineoplastic activity of alpha-tocopherol succinate was focused.
Li
Hongwei
H
School of Public Health, Harbin Medical University, Harbin 150001, China.
Wu
Kun
K
D000970:Antineoplastic Agents / Q000737:chemistry*; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D024505:Tocopherols; D014810:Vitamin E / Q000031:analogs & derivatives* / Q000737:chemistry
D000970:Antineoplastic Agents; D014810:Vitamin E; D024505:Tocopherols