Infantile acute hemorrhagic edema and rotavirus infection.
Infantile acute hemorrhagic edema (AHE) is a benign condition characterized by a dramatic onset of inflammatory edema and ecchymotic purpura in a target or cockade pattern. It is considered an uncommon form of cutaneous vasculitis occurring in children younger than 2 years of age. The outbreak is frequently preceded by an immunization or various infections. We describe an 11-month-old girl with rosette-shaped purpuric plaques on the face and limbs, clinically consistent with a diagnosis of AHE of the skin, associated with fever and diarrhea. Laboratory investigations showed a rotavirus infection, which has not previously been reported in association with AHE of the skin. The disease had a benign course without relapses. Appropriate microbiologic investigations are advisable to confirm the possible etiologic role of rotavirus.
Di Lernia
Vito
V
Operative Unit of Dermatology, 1st Medical Department, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy. vito.dilernia@asmn.re.it
Lombardi
Mara
M
Lo Scocco
Giovanni
G
D003937:Diagnosis, Differential; D004431:Ear, External; D004487:Edema / Q000209:etiology*; D005121:Extremities; D005145:Face; D005260:Female; D006801:Humans; D007223:Infant; D011693:Purpura / Q000209:etiology*; D012400:Rotavirus Infections / Q000150:complications / Q000175:diagnosis* / Q000473:pathology