Resistance in nematode parasites of livestock to the benzimidazole anthelmintics.
The benzimidazoles have served humans well in the continual battle to control nematode parasites among livestock. However, the value of these drugs has been seriously undermined in various countries, particularly in the southern hemisphere, by the development of resistance in the target parasite species. Scientists in many countries are trying to come to grips with this problem, with studies both in the laboratory and the field. However, there are shortcomings with both approaches, particularly the former, which need to be recognized. In this article, Peter Waller discusses these in relation to research into the experimental and epidemiological aspects of benzimidazole resistance.
CSIRO Division of Animal Health, McMaster Laboratory, Private Bag No. 1, Glebe, NSW 2037, Australia.
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