Ciliogenesis: polarity proteins on the move.
The formation and maintenance of cilia and flagella require a selective and directed transport along the axoneme, a characteristic central bundle of microtubules. Recent evidence suggests an interesting link between the generation of cilia and the protein complexes that establish apico-basal cell polarity.
Institut für Genetik, Heinrich-Heine-Universität Düsseldorf, D-40225 Düsseldorf, Germany. olaf.bossinger@uni-duesseldorf.de
Olaf
O
Bossinger
André
A
Bachmann
D016764:Cell Polarity / Q000235:genetics / Q000502:physiology; D002923:Cilia / Q000502:physiology*; D005407:Flagella / Q000502:physiology*; D036341:Intercellular Signaling Peptides and Proteins / Q000235:genetics / Q000502:physiology; D008870:Microtubules / Q000502:physiology*; D008954:Models, Biological; D020409:Molecular Motor Proteins / Q000502:physiology*; D009024:Morphogenesis / Q000502:physiology*; D021381:Protein Transport / Q000502:physiology
D036341:Intercellular Signaling Peptides and Proteins; D020409:Molecular Motor Proteins