A novel strategy for the preparation of arylhydroxylamines: chemoselective reduction of aromatic nitro compounds using bakers' yeast.
Using bakers' yeast as a biocatalyst, the chemoselective reduction of aromatic nitro compounds bearing electron-withdrawing groups gave the corresponding hydroxylamines with good to excellent conversion under mild conditions.
State Key Laboratory of Fine Chemicals, Dalian University of Technology, China.
Feng
F
Li
Jingnan
J
Cui
Xuhong
X
Qian
Rong
R
Zhang
D002851:Chromatography, High Pressure Liquid; D006898:Hydroxylamines / Q000138:chemical synthesis*; D009574:Nitro Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D012441:Saccharomyces cerevisiae / Q000737:chemistry*
D006898:Hydroxylamines; D009574:Nitro Compounds