A novel strategy for the preparation of arylhydroxylamines: chemoselective reduction of aromatic nitro compounds using bakers' yeast.
Using bakers' yeast as a biocatalyst, the chemoselective reduction of aromatic nitro compounds bearing electron-withdrawing groups gave the corresponding hydroxylamines with good to excellent conversion under mild conditions.
Li
Feng
F
State Key Laboratory of Fine Chemicals, Dalian University of Technology, China.
Cui
Jingnan
J
Qian
Xuhong
X
Zhang
Rong
R
D002851:Chromatography, High Pressure Liquid; D006898:Hydroxylamines / Q000138:chemical synthesis*; D009574:Nitro Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D012441:Saccharomyces cerevisiae / Q000737:chemistry*
D006898:Hydroxylamines; D009574:Nitro Compounds