Hormonal correlates for the initiation of breast-feeding in Bangladeshi women.
Hormonal changes that occur before or during parturition are known to trigger early postpartum maternal behaviors in many mammals. In humans, little evidence has been found for hormonal mediation of early postpartum maternal behavior. In this paper, we investigate associations between fetoplacental hormone concentrations in late pregnancy on the time from parturition to initiation of breast-feeding. A sample of 91 pregnant rural Bangladeshi women, enrolled in a 9-month prospective study, provided twice-weekly urine specimens and structured interviews. The subjects provided self-reports of time from parturition to initiation of breast-feeding. Specimens were assayed for urinary concentrations of human chorionic gonadotropin (hCG), pregnanediol-3alpha-glucuronide (PdG, a metabolite of progesterone), and urinary estrone conjugates (E1C). Parametric hazards analysis was used to investigate the effects of hCG, PdG, and E1C concentrations and other covariates (mother's age, parity, and child's sex) on the duration from parturition to breast-feeding. Mother's age, parity, the child's sex, hCG, and PdG showed no association with the onset of breast-feeding. Urinary E1C was significantly associated with time to initiation of breast-feeding, explaining about 4% of the variation in the behavior. The relationship was positive so that higher prepartum concentrations of EIC were associated with later times to initiation of breast-feeding. The direction of this relationship is opposite that found for many other species of mammals but is consistent with some recent findings in primates.
Holman
Darryl J
DJ
Department of Anthropology, University of Washington, Seattle, WA 98195, USA. djholman@u.washington.edu
Grimes
Michael A
MA
Brindle
Eleanor
E
O'Connor
Kathleen A
KA
D000328:Adult; D000367:Age Factors; D001459:Bangladesh / Q000453:epidemiology; D001942:Breast Feeding / Q000706:statistics & numerical data; D006063:Chorionic Gonadotropin / Q000652:urine*; D004970:Estrone / Q000652:urine*; D005260:Female; D006801:Humans; D007774:Lactation / Q000652:urine*; D008297:Male; D008425:Maternal Behavior / Q000502:physiology*; D009034:Mother-Child Relations; D049590:Postpartum Period / Q000652:urine; D011247:Pregnancy / Q000652:urine; D011276:Pregnanediol / Q000031:analogs & derivatives* / Q000652:urine*; D011446:Prospective Studies; D012737:Sex Factors; D013997:Time Factors
D006063:Chorionic Gonadotropin; C022270:pregnanediol-3 alpha-glucuronide; D004970:Estrone; D011276:Pregnanediol