A life-threatening case of stenosing pill hypopharynx-oesophagitis caused by a tamsulosin capsule.
Pill oesophagitis is a frequent clinical entity that may induce dysphagia and exceptionally oesophageal occlusion. The mechanisms inducing mucosal inflammation are not completely defined, but oesophageal damage occurring when the caustic content of a drug remains in the oesophagus long enough to produce mucosal lesions seems to be a main factor. We report a case of a life-threatening stenosing pill hypopharynx-oesophagitis caused by the ingestion of a capsule of tamsulosin, a drug diffusely used for benign prostatic hyperplasia treatment.
D'Agostino
L
L
Department of Clinical and Experimental Medicine, Federico II University, Via S Pansini 5, 80131 Naples, Italy. luciano@unina.it
Manguso
F
F
Bennato
R
R
Scaramuzzo
A
A
D000317:Adrenergic alpha-Antagonists / Q000009:adverse effects; D000368:Aged; D004940:Esophageal Stenosis / Q000139:chemically induced* / Q000175:diagnosis; D004941:Esophagitis / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D007014:Hypophosphatasia / Q000139:chemically induced; D008297:Male; D010612:Pharyngitis / Q000139:chemically induced; D011470:Prostatic Hyperplasia / Q000188:drug therapy; D013449:Sulfonamides / Q000009:adverse effects*; D000077409:Tamsulosin; D014057:Tomography, X-Ray Computed
D000317:Adrenergic alpha-Antagonists; D013449:Sulfonamides; D000077409:Tamsulosin