Mercuric triflate-catalyzed synthesis of 2-methylfurans from 1-alkyn-5-ones.
[reaction: see text] 2-Methylfurans were prepared by an effective cyclization of 1-alkyn-5-ones in the presence of mercuric triflate as the catalyst under very mild reaction conditions with high catalytic turnover up to 100 times. Benzene, toluene, or dichloromethane was the solvent of choice.
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
Hiroshi
H
Imagawa
Takahiro
T
Kurisaki
Mugio
M
Nishizawa