Successful pregnancy and delivery in a young woman with cystic fibrosis and gestational diabetes.
We describe a 23-year-old Delta F508 homozygote cystic fibrosis primigravida. At the onset of gestation, she had mild to moderate pulmonary involvement, exocrine pancreatic insufficiency, focal biliary cirrhosis, satisfactory nutritional status and normal fasting and post-prandial glucose blood levels. At 29 weeks, she developed polyhydramnion and gestational diabetes. At 37 weeks, she was delivered of a live 2,980 g boy by caesarean section under epidural anaesthesia. Insulin was subsequently discontinued and her pulmonary function improved spontaneously. Neither maternal nor neonatal health problems were observed during the 3-month follow-up.
Galli-Tsinopoulou
Assimina
A
4 Department of Pediatrics, Aristotle University of Thessaloniki, P.O. Box 322 Thermi, 57001 Thessaloniki, Greece.
Mamopoulos
Apostolos
A
Panagiotides
Michael
M
Nousia-Arvanitakis
Sanda
S
D000328:Adult; D002585:Cesarean Section; D003550:Cystic Fibrosis / Q000150:complications* / Q000628:therapy; D016640:Diabetes, Gestational / Q000150:complications* / Q000628:therapy; D005260:Female; D020073:Gravidity; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D011256:Pregnancy Outcome; D011295:Prenatal Care / Q000379:methods