Expression of genes coding melatonin and serotonin receptors in rodent skin.
Targeted search for expression of melatonin and serotonin receptors genes in the skin of C57BL/6J mice showed expression of MT1B (but not MT1A). Mouse skin and hamster melanomas also expressed 5HT2B and 5HT7. We identified two novel isoforms of MT1A and 5HT7.
Department of Pathology, University of Tennessee Health Science Center, 930 Madison Ave., Room 519, Memphis, TN 38163, USA. aslominski@utmem.edu
Andrzej
A
Slominski
Alexander
A
Pisarchik
Jacobo
J
Wortsman
D000818:Animals; D006224:Cricetinae; D005260:Female; D005786:Gene Expression Regulation; D008544:Melanocytes / Q000166:cytology / Q000378:metabolism; D008545:Melanoma / Q000378:metabolism; D008647:Mesocricetus; D051379:Mice; D008810:Mice, Inbred C57BL; D008969:Molecular Sequence Data; D010902:Pituitary Gland / Q000166:cytology / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism; D044094:Receptors, Melatonin / Q000235:genetics* / Q000378:metabolism; D011985:Receptors, Serotonin / Q000235:genetics* / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012867:Skin / Q000378:metabolism*; D012878:Skin Neoplasms / Q000378:metabolism; D014407:Tumor Cells, Cultured
D012333:RNA, Messenger; D044094:Receptors, Melatonin; D011985:Receptors, Serotonin