Validation and cross-cultural adjustment of PDQL-questionnaire, Spanish version (Ecuador) (PDQL-EV).
OBJECTIVE
To validate the Ecuadorian Spanish-language version of the Parkinson's Disease Quality of Life Questionnaire (PDQL-EV).


METHODS
Cross-sectional study of patients with Parkinson's Disease attending a Movement Disorders Clinic. MEASURES APPLIED: Hoehn and Yahr (HY), Unified Parkinson's Disease Rating Scale (UPDRS-3.0), Schwab and England Scale (SES), Pfeiffer Questionnaire (SPMSQ), Hospital Anxiety and Depression Scale (HADS). PDQ-39 and PDQL-EV were applied, the latter after translation and back translation.


RESULTS
The study included 137 patients with an age range of 69.43 +/- 10.18 years (mean +/- SD), duration of illness 5.87 +/- 2.58 years, and HY 2.28 +/- 0.77. The PDQL-EV internal consistency (Cronbach's alpha) yielded: Parkinson's symptoms (PS) 0.85; systemic symptoms (SS) 0.69; social function (SF) 0.81; and emotional function (EF) 0.78. The correlation between measurements varied from 0.68 (PS-SS) to 0.46 (SS-EF), and total measurement correlation from 0.58 (EF) to 0.74 (PS) (altogether, p < 0.0001). The correlation of PDQL with clinical variables was: HY -0.62; UPDRS (subscales 1, 2 and 3) -0.55, -0.76, and -0.48, respectively; SES 0.65; SPMSQ -0.35; HADS-anxiety -0.55; HADS-depression -0.67; and PDQ-39 -0.91 (altogether p < 0.0001). PDQL-EV scores were significantly different (p < 0.0001) between moderate and advanced stages, for all domains except for EF (p = 0.006).


CONCLUSIONS
The PDQ-EV has satisfactory internal consistency, and converging and discriminating validity.
Abnormal Movements Clinic, Neurology Department, Carlos Andrade Marín Hospital, Quito, Ecuador. serranom@pi.pro.ec
Marcos
M
Serrano-Dueñas
Pablo
P
Martínez-Martín
Verónica
V
Vaca-Baquero
D000368:Aged; D001007:Anxiety / Q000209:etiology / Q000523:psychology; D003431:Cross-Cultural Comparison; D003430:Cross-Sectional Studies; D003863:Depression / Q000209:etiology / Q000523:psychology; D004484:Ecuador; D004644:Emotions; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life; D012919:Social Behavior; D011795:Surveys and Questionnaires