The role of scavenger receptors in pathogen recognition and innate immunity.
Scavenger receptors represent a large family of structurally unrelated distinct gene products, expressed by myeloid and selected endothelial cells and able to recognise modified low-density lipoproteins. They also bind and internalise a variety of microbial pathogens, as well as modified or endogenous molecules derived from the host, and contribute to a range of physiological or pathological processes.
Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK. subhankar.mukherjee@path.ox.ac.uk
Subhankar
S
Mukhopadhyay
Siamon
S
Gordon
D000818:Animals; D017951:Antigen Presentation; D001419:Bacteria / Q000472:pathogenicity; D005658:Fungi / Q000472:pathogenicity; D007113:Immunity, Innate; D008024:Ligands; D010271:Parasites / Q000472:pathogenicity; D011971:Receptors, Immunologic / Q000276:immunology / Q000502:physiology*; D051116:Receptors, Scavenger; D014780:Viruses / Q000472:pathogenicity
D008024:Ligands; D011971:Receptors, Immunologic; D051116:Receptors, Scavenger