Synthesis and in vitro photodynamic activity of new hexadeca-carboxy phthalocyanines.
Two new hexadeca-carboxy phthalocyanines have been synthesised and evaluated for their photodynamic activities; the zinc(II) analogue exhibits a high class-A scavenger-receptor mediated photocytotoxicity towards the J774 murine macrophage cell line.
Choi
Chi-Fung
CF
Department of Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
Tsang
Po-Ting
PT
Huang
Jian-Dong
JD
Chan
Elaine Y M
EY
Ko
Wing-Hung
WH
Fong
Wing-Ping
WP
Ng
Dennis K P
DK
D000818:Animals; D002460:Cell Line; D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology*; D054833:Isoindoles; D008264:Macrophages / Q000187:drug effects; D051379:Mice; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D013056:Spectrophotometry, Ultraviolet
D007211:Indoles; D054833:Isoindoles; D017319:Photosensitizing Agents; C013647:phthalocyanine