Superoxide production by phagocytic leukocytes: the scientific legacy of Bernard Babior.
It was 32 years ago that Bernard Babior, Ruby Kipnes, and I submitted a paper to the JCI reporting that polymorphonuclear leukocytes produce superoxide (O(2) (-)) during phagocytosis and that this highly reactive oxygen radical might function as a microbicidal agent. The story of how our lab came to this discovery is one of a special relationship between a student and his brilliant mentor.
John T
JT
Curnutte
D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D009504:Neutrophils / Q000378:metabolism*; D010587:Phagocytosis; D013481:Superoxides / Q000378:metabolism*
D013481:Superoxides