Peroxynitrite decomposition catalyst, iron metalloporphyrin, reduces quinolinate-induced neurotoxicity in rats.
Laboratorio de Aminoácidos Excitadores/Departamento de Neuroquímica, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, México D.F. 14269, Mexico.
Dario
D
Santiago-López
Beatriz
B
Vázquez-Román
Verónica
V
Pérez-de La Cruz
Diana
D
Barrera
Daniel
D
Rembao
Citlaltepetl
C
Salinas-Lara
José
J
Pedraza-Chaverrí
Sonia
S
Galván-Arzate
Syed F
SF
Ali
Abel
A
Santamaría
D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D001927:Brain Diseases / Q000139:chemically induced / Q000378:metabolism*; D003342:Corpus Striatum / Q000187:drug effects / Q000378:metabolism; D007501:Iron / Q000378:metabolism*; D008297:Male; D008665:Metalloporphyrins / Q000378:metabolism*; D009498:Neurotoxins / Q000633:toxicity; D009584:Nitrogen / Q000378:metabolism; D018384:Oxidative Stress / Q000187:drug effects; D030421:Peroxynitrous Acid / Q000378:metabolism*; D017378:Quinolinic Acid / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000378:metabolism
D000975:Antioxidants; D008665:Metalloporphyrins; D009498:Neurotoxins; D030421:Peroxynitrous Acid; C002744:3-nitrotyrosine; D014443:Tyrosine; D007501:Iron; D017378:Quinolinic Acid; D009584:Nitrogen