NOD2 mutations and Crohn's disease: are Paneth cells and their antimicrobial peptides the link?
Gastroenterology Unit, Canberra Hospital, Woden ACT 2606, Canberra, Australia.
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D003424:Crohn Disease / Q000235:genetics* / Q000276:immunology; D006801:Humans; D018928:Immunity, Mucosal; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics*; D009154:Mutation / Q000276:immunology*; D053473:Nod2 Signaling Adaptor Protein; D019879:Paneth Cells / Q000276:immunology*; D023084:alpha-Defensins / Q000096:biosynthesis
D047908:Intracellular Signaling Peptides and Proteins; C429018:NOD2 protein, human; D053473:Nod2 Signaling Adaptor Protein; D023084:alpha-Defensins