Fluoride releasing materials: their anti-cariogenic properties tested in in vitro caries models.
The anti-cariogenic properties of three fluoride-releasing materials on root surfaces were evaluated using two different caries models. Standardized cavities were prepared in dentin specimens and restored with either glass-ionomer, resin-modified glass-ionomer, polyacid-modified resin composite or resin composite material. Two groups of 56 specimens were demineralized using a microbial caries model for three days, while another 56 specimens were demineralized using a chemical demineralization model for three days. Lesions around the restorations were measured with a confocal laser scanning microscope. Glass ionomers demonstrated significant anti-cariogenic properties when exposed to the chemical model. However, no significant anti-cariogenic properties were observed with the microbial caries model. In conclusion, the fluoride releasing materials showed different anti-cariogenic properties in root surfaces under the different caries models, suggesting that caution should be exercised when trying to extrapolate the results of in vitro studies to the clinical situation.
Graduate Operative Department, Indiana University School of Dentistry, Indianapolis, IN, USA. lsa@iupui.edu
Lorena Taddei
LT
Sá
Carlos
C
González-Cabezas
Michael A
MA
Cochran
Margherita
M
Fontana
Bruce A
BA
Matis
B Keith
BK
Moore
D002327:Cariostatic Agents / Q000737:chemistry*; D020770:Compomers / Q000737:chemistry; D003188:Composite Resins / Q000737:chemistry; D003731:Dental Caries / Q000139:chemically induced / Q000382:microbiology / Q000517:prevention & control*; D003737:Dental Cavity Preparation; D003764:Dental Materials / Q000737:chemistry*; D003804:Dentin / Q000473:pathology; D005459:Fluorides / Q000737:chemistry*; D005899:Glass Ionomer Cements / Q000737:chemistry; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007780:Lacticaseibacillus casei / Q000502:physiology; D018613:Microscopy, Confocal; D019279:Resin Cements / Q000737:chemistry; D013295:Streptococcus mutans / Q000502:physiology; D013499:Surface Properties; D017001:Tooth Demineralization / Q000139:chemically induced / Q000382:microbiology; D014092:Tooth Root / Q000473:pathology
D002327:Cariostatic Agents; D020770:Compomers; D003188:Composite Resins; D003764:Dental Materials; D005899:Glass Ionomer Cements; D019279:Resin Cements; D005459:Fluorides