Progressive dementia caused by Hashimoto's encephalopathy -- report of two cases.
Dementia induced by Hashimoto's encephalopathy (HE) seems to be a rare condition. We report on two patients, who revealed a syndrome consisting of a rapid progressive dementia with myocloni. In both patients, the detection of antithyroid antibodies enabled the diagnosis of HE. The symptoms receded completely during a high-dose glucocorticoid therapy. In patients with rapidly progressive dementia or with dementia of unknown origin, HE should be considered.
Department of Neurology, University of the Saarland, Homburg/Saar, Germany. nejspi@uniklinik-saarland.de
J
J
Spiegel
D
D
Hellwig
G
G
Becker
M
M
Müller
D000328:Adult; D001927:Brain Diseases / Q000150:complications*; D003704:Dementia / Q000188:drug therapy / Q000209:etiology*; D004569:Electroencephalography / Q000187:drug effects; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009207:Myoclonus / Q000188:drug therapy / Q000209:etiology; D013961:Thyroid Gland / Q000276:immunology; D013967:Thyroiditis, Autoimmune / Q000150:complications*
D005938:Glucocorticoids