Growth hormone deficiency in HIV-infected children following successful treatment with highly active antiretroviral therapy.
Growth failure is common in children with untreated HIV, although growth hormone (GH) deficiency is rare. Treatment with highly active antiretroviral therapy usually results in resumption of normal growth. We report the cases of 2 children with growth failure despite stable full suppression of viremia who were found to be GH deficient.
Department of Pediatrics, University of Maryland, Baltimore, Maryland, USA. dwatson@peds.umaryland.edu <dwatson@peds.umaryland.edu>
Douglas C
DC
Watson
Debra R
DR
Counts
D023241:Antiretroviral Therapy, Highly Active; D002648:Child; D002675:Child, Preschool; D006130:Growth Disorders / Q000188:drug therapy / Q000209:etiology*; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D019382:Human Growth Hormone / Q000172:deficiency* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011994:Recombinant Proteins / Q000627:therapeutic use
D011994:Recombinant Proteins; D019382:Human Growth Hormone