[Association between the level of serum pepsinogen I and markers of the Helicobacter pylori infection in teenagers].
The concentration of pepsinogen I as well as antibodies to Helicobacter pylori and CagA protein were determined in the blood serum in 84 schoolchildren at the age of 14-17 using the immune-enzyme analysis. The level of pepsinogen I did not depend on the sex, age, gastroenterological symptoms and ulcer occurrence in parents. However, the concentration of pepsinogen was higher in teenagers infected with H. pylori (89.6 ug/l) than in non-infected ones (69.4 ug/l, p = 0.012), this increase taking place mostly due to strains containing CagA.
O V
OV
Reshetnikov
S A
SA
Kurilovich
S A
SA
Krotov
V A
VA
Krotova
O V
OV
Shumakova
D000293:Adolescent; D000942:Antigens, Bacterial / Q000276:immunology; D001426:Bacterial Proteins / Q000276:immunology; D015415:Biomarkers / Q000097:blood; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000276:immunology; D006801:Humans; D020116:Pepsinogen A / Q000097:blood*
D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D015415:Biomarkers; C080866:cagA protein, Helicobacter pylori; D020116:Pepsinogen A