Predicted value of renin activity in a woman who had severe ovarian hyperstimulation syndrome with internal jugular vein thrombosis.
OBJECTIVE
To assess plasma renin activity in a patient with severe ovarian hyperstimulation syndrome (OHSS) and internal jugular vein thrombosis.


METHODS
Case report.


METHODS
University-affiliated infertility center.


METHODS
A 33-year-old woman with OHSS and internal jugular vein thrombosis.


METHODS
Controlled ovulation hyperstimulation with recombinant FSH induction.


METHODS
Plasma renin activity (PRA), color Doppler ultrasound of the neck.


RESULTS
The patient had internal jugular vein thrombosis caused by severe OHSS. The PRA was significantly elevated during the acute stage and subsequently declined after resolution of the OHSS.


CONCLUSIONS
In this patient elevated PRA appeared to be associated with the development of OHSS and thrombosis. The implication of the ovarian renin-angiotensin system in the development of OHSS and thrombosis is relevant.
Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, R.O.C.
Fung-Wei
FW
Chang
Chying-Chyuan
CC
Chan
Chang-Sheng
CS
Yin
Gwo-Jang
GJ
Wu
D000032:Abortion, Therapeutic; D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007601:Jugular Veins; D008297:Male; D016471:Ovarian Hyperstimulation Syndrome / Q000097:blood* / Q000150:complications / Q000628:therapy; D011247:Pregnancy; D012083:Renin / Q000097:blood*; D013480:Superovulation; D020246:Venous Thrombosis / Q000097:blood* / Q000150:complications / Q000628:therapy
D000925:Anticoagulants; D012083:Renin