Solitary pulmonary nodules: optimal slice thickness of high-resolution CT in differentiating malignant from benign.
The purpose of this study was to determine an optimal slice thickness that was efficient in differentiating malignant from benign solitary pulmonary nodules (SPNs) on high-resolution computed tomography (HRCT) images. For a total of 92 SPNs, four radiologist indicated their confidence level for the malignant or benign SPN on the CT images presented in 1-, 3-, and 5-mm slice thickness. HRCT could be used to differentiate more accurately the malignant nodules from the benign ones using 1-mm-thick sections than 3- or 5-mm-thick sections.
Department of Radiology, Nagoya University School of Medicine, 65 Tsurumai, Shouwa-ku, Nagoya 466-85500, Japan. iwano45@med.nagoya-u.ac.jp
Shingo
S
Iwano
Naoki
N
Makino
Mitsuru
M
Ikeda
Shigeki
S
Itoh
Masanori
M
Tadokoro
Hiroko
H
Satake
Takeo
T
Ishigaki
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D015331:Cohort Studies; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011336:Probability; D012372:ROC Curve; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging* / Q000473:pathology*; D036542:Tomography, Spiral Computed / Q000379:methods*