[Mechanism and prevention measures of gene silencing].
With the widely application of transgene technology in the fields of high-level biologies, more and more attention was payed to gene silence. Gene silence can take place at the phase of transcription and post-transcription. With the results of methylation, repeated copies and homologous sequence of inner genes, trans-gene are silenced. There are many kinds of mechanisms of gene silencing and here, the mechanisms explaining the gene silence and some prevention measures were summarized in this paper.
South China University of Technology, Guangzhou 510642, China.
Shisong
S
Fang
Pingjian
P
Deng
Shujin
S
Zhao
D019175:DNA Methylation; D020868:Gene Silencing; D034622:RNA Interference; D017385:Sequence Homology; D014158:Transcription, Genetic