Hypolipidemic effect of Coriandrum sativum L. in triton-induced hyperlipidemic rats.
In the biphasic model of triton-induced hyperlipidemia, C. sativum at a dose of 1g/kg body weight reduced cholesterol and triglycerides levels in both synthesis and excretory phases in rats, and the results were comparable with that of Liponil, a commercially available herbal hypolipidemic drug. The results suggest that coriander decreases the uptake and enhances the breakdown of lipids. From the study it can be assumed that coriander has the potential to be popularized as a household herbal remedy with preventive and curative effect against hyperlipidemia.
International Institute of Biotechnology and Toxicology, Department of Toxicology, Padappai 601 301, India. fippat@giasmd01.vsnl.net.in
A Arun Sam
AA
Lal
T
T
Kumar
P Balakrishna
PB
Murthy
K Sadasivan
KS
Pillai
D000818:Animals; D002784:Cholesterol / Q000378:metabolism*; D028526:Coriandrum / Q000737:chemistry*; D006949:Hyperlipidemias / Q000097:blood / Q000139:chemically induced / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal; D011092:Polyethylene Glycols; D051381:Rats; D017208:Rats, Wistar; D014280:Triglycerides / Q000378:metabolism*
D000960:Hypolipidemic Agents; D010936:Plant Extracts; D014280:Triglycerides; D011092:Polyethylene Glycols; D002784:Cholesterol