Solitary pulmonary nodules: optimal slice thickness of high-resolution CT in differentiating malignant from benign.
The purpose of this study was to determine an optimal slice thickness that was efficient in differentiating malignant from benign solitary pulmonary nodules (SPNs) on high-resolution computed tomography (HRCT) images. For a total of 92 SPNs, four radiologist indicated their confidence level for the malignant or benign SPN on the CT images presented in 1-, 3-, and 5-mm slice thickness. HRCT could be used to differentiate more accurately the malignant nodules from the benign ones using 1-mm-thick sections than 3- or 5-mm-thick sections.
Iwano
Shingo
S
Department of Radiology, Nagoya University School of Medicine, 65 Tsurumai, Shouwa-ku, Nagoya 466-85500, Japan. iwano45@med.nagoya-u.ac.jp
Makino
Naoki
N
Ikeda
Mitsuru
M
Itoh
Shigeki
S
Tadokoro
Masanori
M
Satake
Hiroko
H
Ishigaki
Takeo
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D015331:Cohort Studies; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011336:Probability; D012372:ROC Curve; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging* / Q000473:pathology*; D036542:Tomography, Spiral Computed / Q000379:methods*