DNA vaccines against anthrax.
DNA vaccination is vaccination at its simplest. Due to renewed interest in vaccination against anthrax and other biothreat agents, a genetic immunisation approach offers attractive possibilities for rapid, responsive vaccine development. DNA vaccination against anthrax is an active area of research showing promising results at present, which in the short-term and in the future could form the basis for new advances in multi-agent vaccine development. The anthrax 'model' constitutes an important experimental system for genetic immunisation technology development.
Naval Medical Research Center, Biodefense Research Directorate, Silver Spring, MD, USA.
Darrell R
DR
Galloway
Les
L
Baillie
D000818:Animals; D000881:Anthrax / Q000517:prevention & control*; D022122:Anthrax Vaccines / Q000276:immunology; D001408:Bacillus anthracis / Q000235:genetics / Q000276:immunology; D023482:Bioterrorism; D002417:Cattle; D002418:Cattle Diseases / Q000635:transmission; D004269:DNA, Bacterial / Q000276:immunology; D004353:Drug Evaluation, Preclinical; D005260:Female; D006801:Humans; D008253:Macaca mulatta; D008297:Male; D051379:Mice; D010957:Plasmids / Q000008:administration & dosage / Q000235:genetics; D011817:Rabbits; D014611:Vaccination; D019444:Vaccines, DNA / Q000276:immunology
D022122:Anthrax Vaccines; D004269:DNA, Bacterial; D019444:Vaccines, DNA