Ultrasound biomicroscopic analysis of iris profile changes with accommodation in pigmentary glaucoma and relationship to age.
OBJECTIVE
To examine the effect of accommodation on iris profile in pigmentary glaucoma and its relationship to age.


METHODS
Interventional case series.


METHODS
We measured change in iris profile with accommodation in 92 eyes of 92 patients with pigmentary glaucoma.


RESULTS
Mean age was 42 years. Mean change in posterior iris excursion from nonaccommodated to accommodated state was 144.5 microm. (P < .001). Age was plotted against iris excursion with an estimated least-squares regression line. The estimated Pearson correlation coefficient was -0.60, (P < .001). Patients younger than 42 years of age had a mean change in excursion of 209.2 microm compared with 79.8 microm for those patients older than 42 years. (P < .001)


CONCLUSIONS
This study found that there is a significant increase in posterior iris bowing in the accommodated state. Increasing age is associated with decreased posterior iris deviation. These findings add evidence to the theory of accommodation-induced reverse pupillary block in pigmentary glaucoma.
Department of Ophthalmology, Ontario Cancer Institute, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada.
Robert S
RS
Adam
Charles J
CJ
Pavlin
Lawrence J
LJ
Ulanski
D000065:Accommodation, Ocular; D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D005902:Glaucoma, Open-Angle / Q000000981:diagnostic imaging*; D006801:Humans; D007498:Iris / Q000000981:diagnostic imaging*; D008875:Middle Aged; D014463:Ultrasonography