[Progress in nuclear receptor research].
Nuclear receptors belong to a superfamily of ligand-activated transcription factors, which are involved in regulating gene expression in development, cell differentiation, physiological and metabolic processes. In this review we summarize the studies of nuclear receptor and present the progresses in the researches on nuclear receptor and lipid physiology, nuclear receptor and tumor, and nuclear receptor and co-regulators.
Wang
Shui-Liang
SL
Department of medical genetics, Second Military Medical University, Shanghai 200433, China. wangsl72@yahoo.com
Fu
Ji-Liang
JL
D000818:Animals; D004268:DNA-Binding Proteins / Q000502:physiology; D005786:Gene Expression Regulation; D006801:Humans; D050356:Lipid Metabolism; D000071518:Liver X Receptors; D009369:Neoplasms / Q000209:etiology / Q000517:prevention & control; D057093:Orphan Nuclear Receptors; D010802:Phylogeny; D018160:Receptors, Cytoplasmic and Nuclear / Q000737:chemistry / Q000502:physiology*; D014157:Transcription Factors / Q000502:physiology; D000099150:Receptor, Farnesoid X-Activated
D004268:DNA-Binding Proteins; D000071518:Liver X Receptors; D057093:Orphan Nuclear Receptors; D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors; D000099150:Receptor, Farnesoid X-Activated