New elements of the termination of transcription in prokaryotes.
We report here that phased runs of adenines and thymines are very frequent in the neighborhood of 3' of the coding regions of Escherichia coli and Bacillus subtilis. These findings suggest that the DNA curvature could affect transcription termination either directly, through contacts with RNA polymerase, or indirectly, via contacts with some regulatory proteins.
Institute of Evolution, University of Haifa, Haifa 31905, Israel.
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Bolshoy
D000225:Adenine / Q000737:chemistry*; D001412:Bacillus subtilis / Q000378:metabolism*; D004247:DNA / Q000737:chemistry; D012321:DNA-Directed RNA Polymerases / Q000737:chemistry / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism*; D005798:Genes, Bacterial; D015233:Models, Statistical; D013941:Thymine / Q000737:chemistry*; D014158:Transcription, Genetic
D004247:DNA; D012321:DNA-Directed RNA Polymerases; D000225:Adenine; D013941:Thymine