[Enuresis in children with sickle cell disease].
METHODS
In order to analyze epidemiological and clinical characteristics of enuresis in children with sickle cell disease, and identify risk and aetiological factors, 987 subjects (aged 5-20 years) took part in a cross-sectional study. These children were divided into two groups: group 1 consisted of 456 homozygous children with sickle cell disease (haemoglobin SS), while group 2 consisted of 531 normal children. These groups were paired according to age and sex.


RESULTS
The prevalence of enuresis was 50.9% in group 1 and 16.4% in group 2, and was significantly higher (P < 0.05) in the girls. The frequency decreased significantly between the ages of 5-20. At age 16, frequency of enuretic children with sickle cell disease remained statistically greater (15.9% vs. 8.0%). The frequency of wet nights was higher (P < 0.05) in group 1. In addition, anaemia crisis and painful crisis were related to prevalence of enuresis. There was a significant (P < 0.01) negative correlation between haemoglobin F percentage and prevalence of enuresis.


CONCLUSIONS
Enuresis is frequent in children with sickle cell disease and its intensity is linked to severity of disease.
Mabiala Babela
J R
JR
Service de pédiatrie, CHU de Brazzaville, BP 32, Congo. j.mabiala.babela@caramail.com <j.mabiala.babela@caramail.com>
Loumingou
R
R
Pemba-Loufoua
A
A
Londjongo
W
W
Nzingoula
S
S
Senga
P
P
D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004775:Enuresis / Q000453:epidemiology*; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D015995:Prevalence; D012016:Reference Values