Cross-linking dendrimers with allyl ether end-groups using the ring-closing metathesis reaction.
A third generation Frechet-type dendrimer containing 24 allyl ether end-groups was synthesized, cross-linked using the ring-closing metathesis (RCM) reaction, and the core was removed hydrolytically without significant fragmentation. The results are analogous to those previously reported for homoallyl ether dendrimers (Wendland, M. S.; Zimmerman, S. C. J. Am. Chem. Soc. 1999, 121, 1389-1390) suggesting that the less readily available homoallyl ether dendrimers can be replaced by their allyl ethers analogues in a range of applications.
Department of Chemistry, 600 S. Mathews Avenue, University of Illinois, Urbana, Illinois 61801, USA. sczimmer@uiuc.edu
Stephanie L
SL
Elmer
Steven C
SC
Zimmerman
D000498:Allyl Compounds / Q000737:chemistry*; D003432:Cross-Linking Reagents / Q000737:chemistry*; D003500:Cyclization; D004987:Ethers / Q000138:chemical synthesis / Q000737:chemistry*; D008968:Molecular Conformation; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*
D000498:Allyl Compounds; D003432:Cross-Linking Reagents; D004987:Ethers; D011108:Polymers