Candida glabrata periprosthetic infection: a case report and literature review.
We present a case of an immunocompromised host who developed a Candida glabrata infection 20 years after her total knee arthroplasty. She was treated with extensive irrigation and debridement, followed by placement of an amphotericin B cement spacer supplemented with 2 months of oral variconazole. She ultimately underwent an above-knee amputation.
Atlanta Medical Center, Georgia, USA.
Glenn
G
Gaston
John
J
Ogden
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000671:Amputation, Surgical; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D041221:Candida glabrata / Q000302:isolation & purification*; D002177:Candidiasis / Q000188:drug therapy*; D003646:Debridement; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007720:Knee Prosthesis / Q000382:microbiology*; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery*; D012086:Reoperation; D007507:Therapeutic Irrigation; D014640:Vancomycin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D014640:Vancomycin; D000666:Amphotericin B