[Tetrodotoxine-dependent glycine release in the rat nucleus accumbens during correction of feeding behaviour].
Presence of a tone previously paired with a foot-shock in rats during food intake increases the glycine extracellular level in the n. accumbens. The increase will be completely prevented by intra-accumbal infusion of Na-channel blocking agent tetrodotoxine. The findings suggest that glycine mechanisms in the n. accumbens are involved in the correction of feeding behaviour.
Saul'skaia
N B
NB
Solov'eva
N A
NA
D000818:Animals; D004435:Eating / Q000187:drug effects / Q000502:physiology; D005110:Extracellular Space / Q000502:physiology; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology*; D005998:Glycine / Q000378:metabolism*; D017551:Microdialysis; D009714:Nucleus Accumbens / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D026941:Sodium Channel Blockers / Q000494:pharmacology*; D013779:Tetrodotoxin / Q000494:pharmacology*
D026941:Sodium Channel Blockers; D013779:Tetrodotoxin; D005998:Glycine