[Survey on native place and surname of parents in a newborn infant cord blood DNA bank of Han nation].
A hospital-sampled newborn infant cord blood DNA bank was collected to measure the homogeneity comparing with China and northern China population by distribution of native place and surname. The DNA bank included in 566 cases of newborn infant of Han nation in a hospital in Beijing to sample cord blood, parents' native place and surname. The parents' native place and surname were analyzed for distribution, proportion to evaluate their difference with those from China and northern China population data. In the DNA bank, native place of parents from Beijing was from 45.1% to 49.8%, that from Hebei, Shandong, Henan, Jiangsu provinces second from 3.7% to 10.6%, that from other provinces lower than above provinces. The native place of parents covered thirty provinces, municipalities and autonomous regions in China, except Tibet autonomous region and Guizhou province. There were 146 surnames of father and 145 surnames of mother included in the DNA bank. Nine surnames were found more than 1.5% in sampled population. The front eight surnames in order of father were Wang (9.0%), Li (8.0%), Zhang (7.8%), Liu (7.1%), Yang (4.1%), Chen (3.5%), Zhao (3.4%), Gao (1.6%). The front eight surnames in order of mother were Wang (11.8%), Li (8.3%), Zhang (7.8%), Liu (6.4%), Zhao (3.7%), Chen (3.4%), Sun (2.8%), Yang (2.7%). The front seven surnames in order of parents were Wang (10.42%), Li (8.13%), Zhang (7.77%), Liu (6.71%), Zhao (3.53%), Chen (3.45%), Yang (3.36%). The surname distribution of DNA bank was similar to that of north China (Wang 9.87%, Li 9.28%, Zhang 9.13%, Liu 6.68%, Zhao 3.56%, Yang 3.04%, Chen 2.51%) without significance, chi2 = 8.54, df = 6, P = 0.20. The surname in order between DNA bank and northern China was uniform in front fives, the sixth and the seventh reversed. The newborn infant cord blood DNA bank from a hospital in Beijing suggests some feature of the northern China population in surnames Based on the hospital-sampling stratagem, to modify the sampling method might collect suitable newborn infant cord blood DNA bank to fit for human genetic research.
Zhao
Yi-Ming
YM
Center for Clinical Epidemiological Research, Peking University Third Medical School, Beijing 100083, China. yiming-zhao115@163.com
Zhao
Wei-Hong
WH
Cai
Xiao-Ning
XN
Zhu
Ping
P
D002681:China / Q000208:ethnology; D030561:Databases, Nucleic Acid; D005312:Fetal Blood / Q000737:chemistry*; D006801:Humans; D007231:Infant, Newborn; D009275:Names; D010290:Parents