Sclerosing lobular hyperplasia of the breast: fine-needle aspiration cytology findings--a case report.
Sclerosing lobular hyperplasia (SLH) is an uncommon benign lesion seen in the juvenile breast. It presents as a palpable, firm, circumscribed nodular lump in the breast of a young woman. Histologically, it is characterised by prominent lobular hyperplasia and sclerosis of the intralobular connective tissue. We discuss the cytomorphology and differential diagnosis. A 16-yr-old female patient presented with a painless, firm, nodular, mobile mass in the right breast measuring 4 x 4 cm. The clinical and radiological diagnosis was fibroadenoma. Fine-needle aspiration smears showed round to oval ductal epithelial cells in flat sheets and round clusters with an acinar arrangement. A few bare nuclei were seen dispersed in a clean background but no stroma was visualised. A combination of clinical findings, imaging, and cytological features of SLH can help to differentiate this condition from other palpable juvenile breast diseases.
Panikar
Nirupma
N
Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Shahdara, Delhi, India.
Agarwal
Sarla
S
D000293:Adolescent; D044963:Biopsy, Fine-Needle / Q000379:methods*; D001940:Breast / Q000473:pathology* / Q000601:surgery; D001941:Breast Diseases / Q000473:pathology* / Q000601:surgery; D001943:Breast Neoplasms / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000473:pathology; D006801:Humans; D006965:Hyperplasia / Q000473:pathology / Q000601:surgery; D012598:Sclerosis / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome