Red cell deformability and invasion by malaria parasites.
Malaria parasites enter red cells in a multi-step process involving attachment, membrane deformation, invagination and encapsulation. The molecular basis of red cell rigidity is examined by Geoff Pasvol and lain Wilson, and they discuss its effect on the efficiency of invasion by various Plasmodium spp.
Wellcome Senior Lecturer, Nuffield Department of Clinical Medicine, John Radcli f ffe Hospital, Headington, Oxford 0X3 9DU, UK.
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