Linear IgA dermatosis in an immunosuppressed patient after allogenic bone marrow transplantation.
Linear IgA dermatosis (LAD) is a well-recognized acquired subepidermal bullous autoimmune disease. LAD is characterized by clinical, histopathological and immunopathological findings. We report the case of a 38-year-old man who suffered from a chronic myeloic leukaemia. Although he received immunosuppressive therapy he developed LAD after an allogenic bone marrow transplantation. After diagnosis of LAD was established we started a successful systemic therapy with dapsone, while continuing the preliminary medication. Here we report for the first time on a possible relationship between LAD and bone marrow transplantation in an immunosuppressed patient.
Department of Dermatology, University School of Medicine, Essen, Germany.
T
T
Schultewolter
M
M
Goos
J
J
Dissemond
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001327:Autoimmune Diseases / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D003622:Dapsone / Q000627:therapeutic use; D006801:Humans; D016867:Immunocompromised Host; D007070:Immunoglobulin A / Q000276:immunology; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000628:therapy; D008297:Male; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007070:Immunoglobulin A; D003622:Dapsone