Supraumbilical skin rash and fat necrosis after transcatheter arterial chemoembolization: a case report.
We report the case of a 63-year-old female who had chronic hepatitis C and who was diagnosed with hepatocellular carcinoma. Hepatic angiography showed one visible and tortuous falciform artery arising as the terminal branch of the left hepatic artery. Transcatheter arterial chemoembolization (TACE) was performed via the left hepatic artery. The patient developed supraumbilical skin rash with local tenderness on the following day. After supportive treatment by a dermatologist, the skin rash subsided gradually with sequelae of irregular skin surface and one small subcutaneous nodule. Skin biopsy of the lesion 1 year later showed fat necrosis with foreign body reaction and fibrosis. We discuss this rare complication of TACE and review the literature.
Department of Medical Imaging, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chao-Chun
CC
Lin
Ding-Kwo
DK
Wu
Paul Ming-Chen
PM
Shih
Gin-Chung
GC
Liu
Wan-Long
WL
Chuang
D006528:Carcinoma, Hepatocellular / Q000628:therapy; D016461:Chemoembolization, Therapeutic / Q000009:adverse effects*; D005076:Exanthema / Q000209:etiology* / Q000473:pathology; D005218:Fat Necrosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000628:therapy; D008875:Middle Aged