Gestational trophoblastic neoplasia: the management of relapsing patients and other recent advances.
The treatment of gestational trophoblastic neoplasia (GTN) represents one of the modern success stories in cancer medicine. Early diagnosis, effective treatments, monitoring of response with a series of serum human chorionic gonadotropin levels, and centralized care have all contributed to this success. Nevertheless, some patients relapse after initial chemotherapy. This review discusses the routine management of GTN and how to treat relapsed disease.
Sarwar
Naveed
N
Trophoblastic Disease Centre, Department of Medical Oncology, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK.
Newlands
Edward S
ES
Seckl
Michael J
MJ
D005260:Female; D031901:Gestational Trophoblastic Disease / Q000473:pathology / Q000628:therapy*; D006801:Humans; D006828:Hydatidiform Mole / Q000473:pathology; D008495:Medical Oncology / Q000379:methods; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging / Q000379:methods; D011247:Pregnancy; D011379:Prognosis; D012008:Recurrence; D012074:Remission Induction; D014599:Uterus / Q000601:surgery