Cryotherapy simulator for localized prostate cancer.
Cryotherapy is a treatment modality that uses a technique to selectively freeze tissue and thereby cause controlled tissue destruction. The procedure involves placement of multiple small diameter probes through the perineum into the prostate tissue at selected spatial intervals. Transrectal ultrasound is used to properly position the cylindrical probes before activation of the liquid Argon cooling element, which lowers the tissue temperature below -40 degrees Centigrade. Tissue effect is monitored by transrectal ultrasound changes as well as thermocouples placed in the tissue. The computer-based cryotherapy simulation system mimics the major surgical steps involved in the procedure. The simulated real-time ultrasound display is generated from 3-D ultrasound datasets where the interaction of the ultrasound with the instruments as well as the frozen tissue is simulated by image processing. The thermal and mechanical simulations of the tissue are done using a modified finite-difference/finite-element method optimized for real-time performance. The simulator developed is a part of a comprehensive training program, including a computer-based learning system and hands-on training program with a proctor, designed to familiarize the physician with the technique and equipment involved.
Department of Urology, School of Medicine and Health Sciences, The George Washington University, USA.
James K
JK
Hahn
Michael J
MJ
Manyak
Ge
G
Jin
Dongho
D
Kim
John
J
Rewcastle
Sunil
S
Kim
Raymond J
RJ
Walsh
D003198:Computer Simulation; D017679:Cryotherapy / Q000295:instrumentation*; D003626:Data Display; D019160:Endosonography / Q000295:instrumentation*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000295:instrumentation; D008297:Male; D011467:Prostate / Q000000981:diagnostic imaging; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D012984:Software; D014584:User-Computer Interface