What is common to brain activity evoked by the perception of visual and auditory filled durations? A study with MEG and EEG co-recordings.
EEG and MEG scalp data were simultaneously recorded while human participants were performing a duration discrimination task in visual and auditory modality, separately. Short durations were used ranging from 500 to 900 ms, among which participants had to discriminate a previously memorized 700-ms "standard" duration. Behavioral results show accurate but variable performance within and between participants with expected modality effects: the percentage of responses was greater and the mean response time was shorter for auditory than for visual signals. Sustained electric and magnetic activities were obtained correlatively to duration estimation, but with distinct spatiotemporal properties. Electric CNV-like potentials showed fronto-central negativity in both modalities, whereas magnetic sustained fields were distributed with respect to the modality of the interval to be timed. Time courses of these slow brain activities were found to be dependent on stimulus duration but not on its modality nor on the recording signal (EEG or MEG). Source reconstruction demonstrated that these sustained potentials/fields were generated by superimposed contributions from visual and auditory cortices (sustained sensory responses, SSR) and from prefrontal and parietal regions. By using these two complementary techniques, we thus demonstrated the involvement of frontal and parietal cerebral cortex in human timing.
Laboratoire de Neurosciences Cognitives et Imagerie Cérébrale, CNRS UPR640-LENA, Hôpital Salpêtrière, 47 Boulevard de l'Hôpital, 75651 Paris Cedex 13, France. karim.ndiaye@chups.jussieu.fr
Karim
K
N'Diaye
Richard
R
Ragot
Line
L
Garnero
Viviane
V
Pouthas
D000161:Acoustic Stimulation / Q000379:methods; D000328:Adult; D001307:Auditory Perception / Q000502:physiology*; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D003265:Contingent Negative Variation / Q000502:physiology; D004192:Discrimination, Psychological / Q000502:physiology; D004569:Electroencephalography / Q000379:methods; D005071:Evoked Potentials / Q000502:physiology*; D006801:Humans; D015225:Magnetoencephalography / Q000379:methods; D008297:Male; D010775:Photic Stimulation / Q000379:methods; D011930:Reaction Time / Q000502:physiology; D013997:Time Factors; D013998:Time Perception / Q000502:physiology; D014796:Visual Perception / Q000502:physiology*