[Genotypes of Candida dubliniensis in clinical isolates].
Amplification of specific sequences of the ITS1 and ITS2 regions and the intervening 5.8S rRNA gene has lead to the identification of four separate genotypes in Candida dubliniensis. Using primers specific for each genotype, we have studied the prevalence of these genotypes among 68 clinical isolates, mostly from Spanish patients infected by HIV. The majority of the isolates tested belonged to genotype 1 (97%), while only one isolate each from genotypes 2 (1.5%) and 3 (1.5%) were detected in the oral cavity of two patients with HIV infection.
Brena
Sonia
S
Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y odontología, Universidad del País Vasco, Bilbao, Spain.
Rubio
María del Carmen
Mdel C
Salesa
Ricardo
R
Iglesias
Isabel
I
Gil
Joaquina
J
Rezusta
Antonio
A
Moragues
María Dolores
MD
Pontón
José
J
D002175:Candida / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D005838:Genotype; D006801:Humans