The association of diet and other lifestyle factors with the onset of overactive bladder: a longitudinal study in men.
OBJECTIVE
To investigate associations between diet and non-dietary lifestyle factors and the onset of overactive bladder (OAB) in men.


METHODS
Random sample of community-dwelling men aged 40 years plus.


METHODS
Baseline data on urinary symptoms and diet were collected from 5454 men using a postal questionnaire and a food-frequency questionnaire. Follow-up data on urinary symptoms were collected from 4887 men in a postal survey one year later. Logistic regression analysis was used to investigate diet and lifestyle factors associated with onset of OAB in the men without OAB at baseline.


RESULTS
There was a highly significant negative association between beer intake at baseline and subsequent OAB onset (P=0.001), with reduced risk at all levels of intake compared with those who seldom/never drank beer. Adjustment for total alcohol intake (g ethanol day(-1)) reduced the significance of the association (P=0.02). None of the food groups studied was associated with OAB onset, with the possible exception of potatoes (P=0.05), which showed an increased risk of onset at the highest level of consumption. Physical activity, smoking and obesity were not significantly associated.


CONCLUSIONS
While most diet and lifestyle factors were not associated with OAB onset, the evidence from this prospective longitudinal study suggests that beer may have a protective role in the development of OAB. This could be due to a non-alcoholic ingredient as well as the alcohol content.
Dallosso
Helen M
HM
Department of Health Sciences, University of Leicester, UK. Hmd2@le.ac.uk
Matthews
Ruth J
RJ
McGrother
Catherine W
CW
Donaldson
Madeleine M K
MM
Shaw
Chris
C
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001515:Beer; D004032:Diet; D015444:Exercise / Q000502:physiology; D005247:Feeding Behavior / Q000502:physiology*; D006801:Humans; D008019:Life Style; D016015:Logistic Models; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D018570:Risk Assessment; D011198:Solanum tuberosum; D011795:Surveys and Questionnaires; D014549:Urinary Incontinence / Q000453:epidemiology / Q000209:etiology*