Endophthalmitis caused by Klebsiella species.
OBJECTIVE
To investigate clinical settings, antibiotic sensitivities, and visual outcomes associated with endophthalmitis caused by Klebsiella species.


METHODS
Retrospective case series.


METHODS
Record review of patients with endophthalmitis caused by Klebsiella (1984 through 2003).


RESULTS
Clinical settings included cataract surgery (one eye), trauma (two), perforated corneal ulcer (one), and endogenous associated with hepatic abscess (one). Pretreatment vision was hand motions or better in four eyes (80%). Initial treatment was enucleation (one eye), pars plana vitrectomy (two), and vitreous tap and injection (two); intravitreal antibiotics were administered to all nonenucleated eyes. Klebsiella was sensitive to one or more antibiotics administered initially in all cases. In nonenucleated eyes, final acuity was >or=20/400 in two, 1/200 in one, and light perception in one.


CONCLUSIONS
Despite treatment with appropriate antibiotics, endophthalmitis caused by Klebsiella species is associated with generally poor visual outcomes.
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida 33136, USA. iscott@bpei.med.miami.edu <iscott@bpei.med.miami.edu>
Ingrid U
IU
Scott
Neil
N
Matharoo
Harry W
HW
Flynn
Darlene
D
Miller
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D009877:Endophthalmitis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007710:Klebsiella Infections / Q000188:drug therapy / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000302:isolation & purification*; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012189:Retrospective Studies; D014792:Visual Acuity; D014821:Vitrectomy; D014822:Vitreous Body / Q000382:microbiology
D000900:Anti-Bacterial Agents