[Enuresis in children with sickle cell disease].
METHODS
In order to analyze epidemiological and clinical characteristics of enuresis in children with sickle cell disease, and identify risk and aetiological factors, 987 subjects (aged 5-20 years) took part in a cross-sectional study. These children were divided into two groups: group 1 consisted of 456 homozygous children with sickle cell disease (haemoglobin SS), while group 2 consisted of 531 normal children. These groups were paired according to age and sex.


RESULTS
The prevalence of enuresis was 50.9% in group 1 and 16.4% in group 2, and was significantly higher (P < 0.05) in the girls. The frequency decreased significantly between the ages of 5-20. At age 16, frequency of enuretic children with sickle cell disease remained statistically greater (15.9% vs. 8.0%). The frequency of wet nights was higher (P < 0.05) in group 1. In addition, anaemia crisis and painful crisis were related to prevalence of enuresis. There was a significant (P < 0.01) negative correlation between haemoglobin F percentage and prevalence of enuresis.


CONCLUSIONS
Enuresis is frequent in children with sickle cell disease and its intensity is linked to severity of disease.
Service de pédiatrie, CHU de Brazzaville, BP 32, Congo. j.mabiala.babela@caramail.com <j.mabiala.babela@caramail.com>
J R
JR
Mabiala Babela
R
R
Loumingou
A
A
Pemba-Loufoua
W
W
Londjongo
S
S
Nzingoula
P
P
Senga
D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004775:Enuresis / Q000453:epidemiology*; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D015995:Prevalence; D012016:Reference Values