[Mapping quantitative trait loci for meat quality trait in a Large White x Meishan cross].
To search for the chromosome regions for quantitative trait loci (QTL) affecting meat quality in pigs, a three-generation resource family was developed in China using three Large White grand sires and seven Meishan grand dams. A total of 147 F2 progenies derived from two populations in 1998 (n = 81) and 2000 (n = 66) were phenotyped for meat quality. All animals were typed for 48 microsatellite markers covering six chromosomes: 1, 2, 3, 4, 6 and 7. Linear model and least square analyses were used for interval mapping meat quality in jointed population and single population, permutation for empirical threshold. The strongest linkage at chromosome-wide level (P < 0.01) and genome-wide level (P < 0.05) on chromosome 4 affecting intramuscular fat (IMF) QTL from the population in 2000 was detected with explained phenotypic variance of 5.24%, and Meishan's QTL increased the intramuscular fat content. There was a suggestive QTL for IMF near the threshold of chromosome-wide in the same region in jointly population. The QTL for pH value in m. Semispinalis Capitis and m. Biceps Femoris were located on chromosomes 1 and 3, respectively. One and three QTL affecting WHC reached the thresholds of chromosome-wide level in the populations of 1998 and 2000, respectively. In the population of 1998, QTL for moisture content at chromosome-wide level was on SSC6 and in jointed populations were on SSC2, 6 and 7. There were imprinting effects in moisture content QTL, and Meishan and Large White pigs all had favorable effects influencing moisture on different chromosomes.
College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. yuhongsu652@163.net
Yu-Hong
YH
Su
Yuan-Zhu
YZ
Xiong
Si-Wen
SW
Jiang
Qin
Q
Zhang
Ming-Gang
MG
Lei
Rong
R
Zheng
Chang-Yan
CY
Deng
D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D003433:Crosses, Genetic; D006863:Hydrogen-Ion Concentration; D008460:Meat / Q000592:standards*; D010641:Phenotype; D040641:Quantitative Trait Loci; D013552:Swine / Q000235:genetics* / Q000378:metabolism; D014867:Water
D014867:Water