Laser microdissection microscopy in parasitology: microscopes meet thermocyclers.
The new methods of laser microdissection microscopy have received wide acceptance in biology and have been applied in a small number of parasitology investigations. Here, the techniques and applications of laser microdissection microscopy are reviewed with suggestions of how the systems might be used to explore applied questions in parasite molecular biology and host-parasite interactions.
Jones
Malcolm K
MK
Australian Centre for International and Tropical and International Health and Nutrition, Queensland Institute of Medical Research, Herston, Queensland 4029, Australia. malcolmJ@qimr.edu.au <malcolmJ@qimr.edu.au>
Randall
Louise M
LM
McManus
Donald P
DP
Engwerda
Christian R
CR
D000818:Animals; D006790:Host-Parasite Interactions / Q000502:physiology; D018613:Microscopy, Confocal / Q000379:methods*; D008967:Molecular Biology; D010271:Parasites / Q000033:anatomy & histology* / Q000648:ultrastructure*; D040901:Proteomics