Incontinentia pigmenti achromians (Ito).
A patient with incontinentia pigmenti achromians was reported. She displayed other abnormalities such as a saddle nose, malformed auricles, growth retardation, convulsions and abnormal EEG. Histopathologically, a partial decrease in melanin granules in the basal layer and the presence of melanocytes which showed a weak dopa reaction were the main findings. The hypofunction of melanin production was detected by electron microscopy.
Department of Dermatology, Osaka University School of Medicine, Fukushimaku, Osaka, Japan.
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Hata
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Endo
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Yabuuchi
D000015:Abnormalities, Multiple / Q000175:diagnosis*; D001707:Biopsy, Needle; D002675:Child, Preschool; D005260:Female; D006130:Growth Disorders / Q000175:diagnosis; D006801:Humans; D007150:Immunohistochemistry; D007564:Japan; D001523:Mental Disorders / Q000175:diagnosis; D008854:Microscopy, Electron; D010859:Pigmentation Disorders / Q000175:diagnosis / Q000473:pathology*; D011379:Prognosis; D018570:Risk Assessment; D012867:Skin / Q000473:pathology / Q000648:ultrastructure*