[Freezing of gait is a symptom of Parkinson disease].
One could distinguish between "off freezing", which is a symptom tightly bound to L-dopa dosage and titration, and is clinically bound to wearing off, and, on the contrary, "on freezing" which does not respond to therapy modifications or to different drug's titration. On freezing seems to be related to frontal-basal ganglia-pontine neural pathway disruption. This neural disruption may be related with altered perception of extra and peri-personal space which are two major problems of these patients. We demonstrate in a group of patients with "on freezing" evident defect of attention, focus capability, of set-shifting properties, and of alteration in body/space relationship. We discuss on results obtained by specific training of physiotherapy with an review on literature.
Mezzarobba
Susanna
S
Corso di Laurea in Fisioterapia, UCO Clinica Neurologica, Università, Trieste.
Bandel
Dora
D
Capus
Livio
L
Torre
Paola
P
Moretti
Rita
R
D000978:Antiparkinson Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D001288:Attention; D005260:Female; D005684:Gait; D006801:Humans; D007980:Levodopa / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D010300:Parkinson Disease / Q000188:drug therapy / Q000503:physiopathology* / Q000534:rehabilitation*; D026741:Physical Therapy Modalities; D011597:Psychomotor Performance; D013028:Space Perception; D013997:Time Factors
D000978:Antiparkinson Agents; D007980:Levodopa