Alcohol intake and incidence of de novo adult acute leukemia.
In a case-control study of adult acute leukemia we defined alcohol intake as either non-regular (<1 drink per week), light (1-5 drinks per week), moderate (6-8 drinks per week) or heavy (>8 drinks per week). An inverse association was found for light and moderate beer intake (RR = 0.58; 95% CI: 0.44, 0.76). In contrast, a positive association was found for moderate and heavy wine intake (RR = 2.1; 95% CI: 1.2, 3.8). Divergent results might reflect the effect of different nutrients in beer and wine, unmeasured confounding, or differing impacts of selection bias on these associations.
School of Public Health, Division of Epidemiology and Biostatistics, University of Illinois at Chicago, 816 SPHPI (M/C 923), 1603 W. Taylor, Chicago, IL 60612, USA. garthr@uic.edu
Garth H
GH
Rauscher
David
D
Shore
Dale P
DP
Sandler
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects*; D001515:Beer / Q000009:adverse effects; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D015994:Incidence; D007938:Leukemia / Q000139:chemically induced* / Q000209:etiology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009656:North America; D012306:Risk; D014920:Wine / Q000009:adverse effects