Strength vs aerobic training in children with cystic fibrosis: a randomized controlled trial.
OBJECTIVE
Exercise has the potential to improve the ability of a patient with cystic fibrosis (CF) to cope with the physical demands of everyday life, and may improve prognosis. The purpose of this study was to compare the effects of a home-based, semi-supervised, upper-body strength-training regimen with a similarly structured aerobic training regimen.


METHODS
Data were collected during a 1-year randomized clinical trial.


METHODS
Counselors conducted in-home visits with the participants once per week for the first 8 weeks followed by monthly visits for the remainder of the study.


METHODS
Sixty-seven patients with CF, aged 8 to 18 years, participated in the trial.


METHODS
Participants in both exercise conditions were encouraged to exercise at least three times per week for 1 year. Each child in the aerobic group was given a stair-stepping machine, and each child in the upper-body strength training group was given an upper-body-only weight-resistance machine.


RESULTS
Aerobic fitness, pulmonary function, quality of life, and strength were measured at baseline, at 6 months, and at 12 months. Strength training increased the maximum weight lifted for biceps curls significantly more than aerobic training (p < 0.02). However, this differential did not remain significant after control for increase in height. Both training procedures were associated with increased strength (p < 0.002) and physical work capacity (PWC) [p < 0.033].


CONCLUSIONS
We concluded that strength and aerobic training may increase upper-body strength, and that both types of training may increase PWC for children with CF. Future trials should be conducted with no-training control subjects and larger samples to increase statistical power.
Orenstein
David M
DM
Center for Behavioral Epidemiology and Community Health, 9245 Sky Park Court, Suite 230, San Diego, CA 92123, USA.
Hovell
Melbourne F
MF
Mulvihill
Mary
M
Keating
Kristen K
KK
Hofstetter
C Richard
CR
Kelsey
Sheryl
S
Morris
Kimberly
K
Nixon
Patricia A
PA
D000293:Adolescent; D002648:Child; D003550:Cystic Fibrosis / Q000534:rehabilitation*; D005081:Exercise Therapy / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D010809:Physical Fitness; D011446:Prospective Studies; D011788:Quality of Life; D012129:Respiratory Function Tests; D016896:Treatment Outcome