Kinetics of neuronal and endocrine secretion.
Calcium (Ca2+) regulated secretion/exocytosis is a key mechanism for cell-cell communication. Neurotransmission and hormone release are the most studied and the best characterized of all secretion systems so far. Here, some dynamic aspects of secretory vesicle trafficking will be briefly reviewed with special emphasis on the differences between synaptic vesicle and dense-core vesicle turnover.
San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. ottavio.cremona@hsr.it
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Cremona
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Collesi
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Raiteri
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Benfenati
D000818:Animals; D004594:Electrophysiology; D004705:Endocytosis / Q000502:physiology; D005089:Exocytosis / Q000502:physiology; D006801:Humans; D007700:Kinetics; D009474:Neurons / Q000378:metabolism* / Q000648:ultrastructure; D009490:Neurosecretory Systems / Q000166:cytology / Q000502:physiology*; D013572:Synaptic Vesicles / Q000502:physiology / Q000648:ultrastructure