SCID mice as models for parasitic infections.
Mice with severe combined immunodeficiency (SCID mice) have become a favored model system for the study of many parasitic diseases. In this review, Samuel Stanley Jr and Herbert Virgin IV provide a brief overview of the biology of the SCID mouse, and review some examples of how the SCID mouse model has been applied to the study of the immunology of a number of different parasitic diseases.
Departments of Medicine and Molecular Microbiology, Washington University School of Medicine, St Louis, MO 63110, USA.
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