[A method for improving measuring accuracy in multi-channel impedance spectroscopy (MIS)].
The use of impedance spectroscopy as a diagnostic tool for the investigation of biological objects involves the consideration of numerous parameters impacting on measuring accuracy. This paper describes a calibration method for multichannel instruments that reduces the non-inconsiderable influence of frequency response variations between the channels, thus significantly increasing measuring accuracy. The method is tested in a recently developed, high-resolution, multi-channel bio-impedance analyser. Reduction of the measuring error is demonstrated, and the magnitude and phase resolution is quantified. The advantage of this method lies in its applicability to existing systems. Furthermore, an additional calibration impedance is not needed.
Institut für Biomedizinische Technik und Krankenhaustechnik, Medizinische Hochschule Hannover. florian.thiel@ptb.de
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D000465:Algorithms; D000818:Animals; D002138:Calibration; D017097:Electric Impedance; D006801:Humans; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013057:Spectrum Analysis / Q000295:instrumentation* / Q000379:methods*