Whooping cough due to Bordetella parapertussis: an unresolved problem.
Bordetella parapertussis is one of the bacteria that causes whooping cough. However, little attention has been paid to this bacterium because it causes a milder illness than Bordetella pertussis and the rate of detection is low, even though research suggests that pertussis vaccines have limited efficacy against B. parapertussis infection. However, recent studies have revealed high rates of detection in patients with whooping cough in some field studies. In this review, the relevant studies of B. parapertussis are summarized and it is demonstrated that it is now necessary to pay greater attention to infections by this bacterium.
Watanabe
Mineo
M
University of Cincinnati, Department of Molecular Genetics, Biochemistry and Microbiology, 231 Albert Sabin way, Cincinnati, OH 45267-0524, USA. mineo.watanabe@uc.edu
Nagai
Masaaki
M
D000818:Animals; D042483:Bordetella parapertussis / Q000472:pathogenicity; D001886:Bordetella pertussis / Q000472:pathogenicity; D002986:Clinical Trials as Topic; D003937:Diagnosis, Differential; D006801:Humans; D010567:Pertussis Vaccine / Q000627:therapeutic use; D014917:Whooping Cough / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology* / Q000503:physiopathology
D010567:Pertussis Vaccine