Calcium and salinity sensing by the thick ascending limb: a journey from mammals to fish and back again.
The roles of the CaSR in endocrine, epithelial, CNS, and other cells have been reviewed previously [17-19, 20, 27-30, 31-33]. This brief review focuses on the roles of the CaSR in the thick ascending limb of Henle (TAL), and is written in honor of my mentor and long-term friend and colleague, Thomas E. Andreoli, on the occasion of his retirement. My early studies of TAL function with Tom Andreoli were the inspiration for this work.
Hebert
Steven C
SC
Department of Cellular and Molecular Physiology, Yale University School of Medicine, 333 Cedar Street, SHM B147, P.O. Box 208026, SA115 New Haven, CT 06525-8026 , USA. steven.hebert@yale.edu
D000818:Animals; D001693:Biological Transport, Active; D002118:Calcium / Q000097:blood; D005399:Fishes; D006801:Humans; D007686:Kidney Tubules, Distal / Q000502:physiology*; D008138:Loop of Henle / Q000502:physiology*; D044169:Receptors, Calcium-Sensing / Q000502:physiology*; D012964:Sodium / Q000378:metabolism
D044169:Receptors, Calcium-Sensing; D012964:Sodium; D002118:Calcium