The distribution and chemical coding of neurons in the celiac-superior mesenteric ganglion complex supplying the normal and inflamed ileum in the pig.
The present study investigated the chemical coding of neurons in the celiac-superior mesenteric ganglion complex supplying the normal (n=4) and inflamed (n=4) ileum (chemically-induced inflammation) in juvenile pigs using retrograde tracing combined with immunohistochemistry. Ileum-projecting neurons (IPN) were predominantly distributed in the left and right superior mesenteric pools of the ganglion. The majority of them were adrenergic (tyrosine hydroxylase-positive) and also contained neuropeptide Y, somatostatin or galanin. No clear-cut differences in the distribution and chemical coding of IPN were found between normal and inflamed pigs. However, in the inflamed group, the density of peptidergic, IPN-associated nerve fibres was higher than that found in the control group.
Kaleczyc
J
J
Department of Functional Morphology, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13, 10-719 Olsztyn, Poland. jerzyk@uwm.edu.pl
Pidsudko
Z
Z
Franke-Radowiecka
A
A
Sienkiewicz
W
W
Majewski
M
M
Lakomy
M
M
Timmermans
J P
JP
D000818:Animals; D000831:Animals, Newborn; D016022:Case-Control Studies; D017615:Enteric Nervous System / Q000166:cytology*; D005260:Female; D005725:Ganglia, Autonomic / Q000166:cytology*; D007082:Ileum / Q000294:innervation*; D007150:Immunohistochemistry / Q000662:veterinary; D009474:Neurons / Q000737:chemistry / Q000166:cytology* / Q000378:metabolism; D013552:Swine