Effect of dietary fish oil on body fat mass and basal fat oxidation in healthy adults.
OBJECTIVE
To investigate whether the substitution of fish oil for visible fats in a control diet (52% carbohydrates, 16% protein, 32% fat; P:S 0.2) influences body fat mass and substrate oxidation in healthy adults.


METHODS
Six volunteers (5 men; 23 +/- 2 y; BMI: 21.9 +/- 1.6) were fed a control diet (C) ad libitum during a period of three weeks and, 10-12 weeks later, the same diet where 6 g/d of visible fat were replaced by 6 g/d of fish oil (FO) for another three weeks.


RESULTS
Energy intakes (IKA-calorimeter) were unchanged. Body fat mass (Dual-energy X-ray absorptiometry) decreased with FO (-0.88 +/- 0.16 vs -0.3 +/- 0.34 kg; FO vs C; P < 0.05). When adjusted for lean body mass (Ancova), resting metabolic rate (indirect calorimetry) was unchanged. Basal respiratory quotient decreased with FO (0.815 +/- 0.02 vs 0.834 +/- 0.02; P < 0.05) and basal lipid oxidation increased with FO (1.06 +/- 0.17 vs 0.87 +/- 0.13 mg kg(-1) min(-1); P < 0.05).


CONCLUSIONS
Dietary FO reduces body fat mass and stimulates lipid oxidation in healthy adults.
Couet
C
C
Laboratoire de Nutrition et Clinique Médicale A, J.E. 313, Université François Rabelais, 37000 Tours, France.
Delarue
J
J
Ritz
P
P
Antoine
J M
JM
Lamisse
F
F
D000328:Adult; D001481:Basal Metabolism; D001823:Body Composition; D002153:Calorimetry, Indirect; D003720:Densitometry; D002149:Energy Intake; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage; D005260:Female; D005395:Fish Oils / Q000008:administration & dosage*; D006801:Humans; D016014:Linear Models; D050356:Lipid Metabolism; D008297:Male; D010084:Oxidation-Reduction
D015525:Fatty Acids, Omega-3; D005395:Fish Oils