[The study of cerebral oxygenation and central hemodynamics in patients with ischemic heart disease at rest and during physical effort.].
Cerebral oxygenation (rSO(2)) in the region of sagittal sinus and main hemodynamic parameters were measured in 112 patients with ischemic heart disease and class II-III angina. Four groups of patients were distinguished according to degree of rSO(2) lowering. Hemodynamics and oxygen transport function of the blood were proportionally related to degree of rSO(2) lowering. Normal rSO(2) (>70%) and degree lower (70-61%) was associated with predicted (desirable) cerebral blood flow. Lower rSO(2) values (60-50%) were accompanied with increased oxygen utilization (by 20-25%). Critical rSO(2) lowering (below 50%) was associated with>/=75% rise of oxygen utilization what was indicative of decreased brain blood flow and cerebral ischemia.
E. N. Meshalkin Research Institute for Circulation Patology, Novosibirsk.
G N
GN
Okuneva
E N
EN
Levicheva
A M
AM
Cherniavskiĭ
V V
VV
Marcheva
A V
AV
Shun'kin
S P
SP
Mironenko
M N
MN
Deriagin
D002560:Cerebrovascular Circulation; D006439:Hemodynamics; D006801:Humans; D017202:Myocardial Ischemia; D010100:Oxygen; D005082:Physical Exertion; D019265:Spectroscopy, Near-Infrared
D010100:Oxygen