Epithelial ion transport - possible contribution to parasite expulsion.
Multiple local effector mechanisms contribute to host protection from multicellular parasites. In this article, Alan Baird and Kate O'Malley describe a technique for voltage clamping isolated intestinal mucosae obtained from previously parasitized animals. Antigen challenge evoked an ion transport response which is the mechanism underlying net fluid secretion that may contribute to repulsion of enteric-dwelling parasites.
Department of Pharmacology, University College Dublin, Dublin 4, Republic of Ireland.
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AW
Baird
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KE
O'Malley