Effects of ultraviolet B irradiation on cutaneous leishmaniasis.
Protection against many infectious diseases is mediated by cellular immunity in the competent host. Ultraviolet (UV) radiation, a component of sunlight, is a potent suppressor of cell-mediated immune responses. Suzanne Holmes Giannini discusses the possible relevance of ambient levels of UVB to pathogenesis and immunity in infectious diseases, with special reference to cutaneous leishmaniasis.
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University of Maryland School of Medicine, Department of Microbiology and Immunology, 655 West Baltimore Street, Baltimore, MD 21201, USA.