Studies on the constituents of Swertia japonica MAKINO I. On the structures of new secoiridoid diglycosides.
Eight new secoiridoid diglycosides, 6'-O-alpha-L-arabinopyranosylswertiamarin (1), 3'-O-beta-D-glucopyranosylswertiamarin (2), 4'-O-beta-D-glucopyranosylswertiamarin (3), 3'-O-beta-D-galactopyranosylswertiamarin (4), 6'-O-alpha-D-galactopyranosylswertiamarin (5), 6'-O-alpha-D-mannopyranosylswertiamarin (6), 6'-O-beta-D-fructofuranosylswertiamarin (7) and 5''-O-beta-D-glucopyranosylamaroswerin (12), were isolated, together with five known compounds from the whole plants of Swertia japonica MAKINO. The structures of the new compounds were elucidated on the basis of chemical and spectroscopic evidence. Compounds 6 and 7 are the first naturally occuring iridoid diglycosides having an alpha-D-mannopyranosyl unit and beta-D-fructofuranosyl unit, respectively.
Tohoku Pharmaceutical University, Miyagi, Japan.
Masafumi
M
Kikuchi
Masao
M
Kikuchi
D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D039823:Iridoids / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry; D029967:Swertia
D006027:Glycosides; D039823:Iridoids; D010936:Plant Extracts