The hazard of malarial nephropathy.
Renal damage in malaria occurs as a result of two distinct mechanisms: microcirculatory disturbance, which is confined to falciparum malaria, and immunological damage through the deposition of soluble immune complexes. Quartan malarial nephropathy, due to Plasmodium malariae, is a progressive disease ending in chronic, hypertensive, renal failure. The disease seems most prevalent in adolescents, placing a heavy burden on the health services of developing countries where falciparum malaria is endemic.
Kibukamusoke
J W
JW
John Curtin School for Medical Research, Australian National University, Canberra, Australia.