New method for detection of Mycobacterium tuberculosis Direct Test inhibitors in clinical specimens.
Existing protocols for the detection of Mycobacterium tuberculosis Direct Test (MDT) inhibitors require substantial quantities of specimen and cannot distinguish Mycobacterium tuberculosis complex from other mycobacteria if inhibitors are present. We describe a preliminary evaluation of a simple and practical protocol for MTD inhibitor testing that circumvents these difficulties.
Sloutsky
A
A
Massachusetts State Laboratory Institute, Boston, MA 02130, USA. alex.sloutsky@state.ma.us
Han
L L
LL
Werner
B G
BG
D001431:Bacteriological Techniques; D005260:Female; D006801:Humans; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D012329:RNA, Bacterial / Q000032:analysis; D012189:Retrospective Studies; D012494:Sampling Studies; D012680:Sensitivity and Specificity; D013048:Specimen Handling
D012329:RNA, Bacterial