[Evaluation of renal blood flow by Doppler study in children and adolescents with type 1 diabetes].
Renal blood flow was ultrasonographically studied in 220 children, adolescents, and young, postpubertal patients who had fell ill with type 1 diabetes mellitus (DM) in childhood (of them there were 111 (49.8%) males and 112 (50.2%) females with a disease history of 1 to 27 years (73 patients with diabetic nephropathy (DN) and 150 without DN). Thirty apparently healthy children and adolescents made up a comparison group. Doppler duplex scanning and Doppler pulse-wave study (DPWS) were made at the level of the great renal artery, segmental, interlobar, and arcuate arteries. With DPWS, the values of peripheral resistance were lower than the normal values at the level of interlobar and arcuate arteries in all patients with microangiopathies. There were significant differences between the groups of patients with different types of microangiopathies, the group of patients with DM without DMA, and the control group. Echography was used to determine the volumes of the kidneys in 220 patients. In patients with DM, renal volume was significantly greater than that in the control patients (p<0.05).
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Pykov
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Trufanova
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Sivous
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003928:Diabetic Nephropathies / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging*; D008297:Male; D012077:Renal Artery / Q000000981:diagnostic imaging; D012079:Renal Circulation; D013997:Time Factors; D018608:Ultrasonography, Doppler