Impact of anemia on outcomes of patients undergoing percutaneous coronary interventions.
Of 6,929 consecutive patients who were treated with percutaneous coronary intervention, 1,708 (24.6%) had anemia according to criteria of the World Health Organization. Compared with patients who did not have anemia, those who did have anemia were older, more frequently women and African-American, had a smaller body mass index, and higher frequencies of cardiovascular risk factors and co-morbid conditions. Patients who had anemia compared with those who did not have anemia had significantly (p <0.0001) higher mortality rates during hospitalization (1.9% vs 0.4%) and at 1 year (12.8% vs 3.5%). After adjustment for potential confounders, baseline hematocrit remained a significant predictor of a 1-year mortality rate (hazard ratio 0.93 per 1% increase in hematocrit, 95% confidence interval 0.91 to 0.95).
Nikolsky
Eugenia
E
Cardiovascular Research Foundation and Columbia University Medical Center, New York, New York 10022, USA.
Mehran
Roxana
R
Aymong
Eve D
ED
Mintz
Gary S
GS
Lansky
Alexandra J
AJ
Lasic
Zoran
Z
Negoita
Manuela
M
Fahy
Martin
M
Pocock
Stuart J
SJ
Na
Yingbo
Y
Krieger
Shoshana
S
Moses
Jeffrey W
JW
Stone
Gregg W
GW
Leon
Martin B
MB
Dangas
George
G
D000368:Aged; D000740:Anemia / Q000150:complications* / Q000453:epidemiology; D015906:Angioplasty, Balloon, Coronary; D003327:Coronary Disease / Q000150:complications* / Q000628:therapy*; D005260:Female; D006400:Hematocrit; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D016896:Treatment Outcome