Diagnosis of Chagas disease using recombinant DNA technology.
In this article, Alberto Frasch and Maria Reyes discuss the development of new tools for the serodiagnosis of Chagas disease (caused by Trypanosoma cruzi) and describe recombinant antigens that have proved to be of great diagnostic potential in distinguishing different stages of the disease. The work is important because different treatment strategies are needed for acute and chronic infection.
Instituto de Investigaciones Bioquímicas Fundación Campomar, Antonio Machado 151, 1405 Buenos Aires, Argentina.
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Frasch
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Reyes