Recovery and rehabilitation in stroke: stem cells.
The recent demonstration that neurons for transplantation can be generated from stem cells and that the adult brain produces new neurons in response to stroke has raised hope for the development of a stem cell therapy for patients affected with this disorder. In this review we propose a road map to the clinic and describe the different scientific tasks that need to be accomplished to move stem cell-based approaches toward application in stroke patients.
Lindvall
Olle
O
Laboratory of Neurogenesis and Cell Therapy, Wallenberg Neuroscience Center, University Hospital BMC A-11, Lund, Sweden. olle.lindvall@neurol.lu.se
Kokaia
Zaal
Z
D000818:Animals; D004195:Disease Models, Animal; D006801:Humans; D033581:Stem Cell Transplantation; D020521:Stroke / Q000628:therapy; D000071939:Stroke Rehabilitation