[The influence of systemically administered selective dopamine antagonists of D1 and D2/D3 types on alimentary and escape conditioned placing reactions in cats].
Systemic administration of the specific antagonists of D1 (SCH23390, 0.005-0.1 mg/kg) and D2/D3 (raclopride, 0.1-0.25 mg/kg) dopamine receptors leeds to dose-dependent increase of the reaction time and decrease of conditined reflex probability up to full blocking (in the case of SCH23390) of alimentary and escape conditioned placing reaction in cats. The action of both antagonists was far more suppressive regarding conditioned escape reflex. The action of SCH23390 was far more effective than that of raclopride concerning both types of conditioned reflexes.
D000818:Animals; D001552:Benzazepines / Q000008:administration & dosage / Q000494:pharmacology*; D002415:Cats; D003214:Conditioning, Classical; D018492:Dopamine Antagonists / Q000008:administration & dosage / Q000494:pharmacology*; D065127:Dopamine D2 Receptor Antagonists; D004924:Escape Reaction / Q000187:drug effects*; D005247:Feeding Behavior / Q000187:drug effects; D020891:Raclopride / Q000008:administration & dosage / Q000494:pharmacology*; D017447:Receptors, Dopamine D1 / Q000037:antagonists & inhibitors; D050637:Receptors, Dopamine D3
D001552:Benzazepines; D018492:Dopamine Antagonists; D065127:Dopamine D2 Receptor Antagonists; D017447:Receptors, Dopamine D1; D050637:Receptors, Dopamine D3; D020891:Raclopride