Progress towards a defined vaccine for schistosomiasis.
During the last five years considerable progress has been made in studies o f schistosome immunology. Convergent views have emerged from the study of human and animal immunity which agree on the mechanisms required and the antigens involved. The reproducible induction of protective immunity with attenuated parasites and with antigenic preparations has now led to agreement that vaccination against schistosomiosis is on achievable goal. The evidence that led to this optimistic view was reviewed at a scientific working group on 'Prospects for Immunological Intervention in Human Schistosomiosis' held in Geneva in May 1986, under the auspices of the UNDP/World Bonk/WHO Special Programme.
National Institute for Medical Research, London NW7 IAA, UK.
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