Relationship between the appearance of preantral follicles in the fetal ovary of Antarctic minke whales (Balaenoptera bonaerensis) and hormone concentrations in the fetal heart, umbilical cord and maternal blood.
The present study aimed to determine the relationship among changes in the number of preantral follicles and concentrations of follicle-stimulating hormone (FSH), luteinizing hormone (LH), progesterone (P4), androstenedione (A) and estradiol-17beta (E2) in the fetal heart, umbilical cord and maternal blood. Primordial follicles had already appeared in a 20 cm fetus and primary follicles were observed in a 50 cm fetus. In a 70 cm fetus, the number of primordial and primary follicles increased rapidly and secondary follicles were present. The concentrations of LH and FSH did not change between 20 cm and 160 cm in fetal length. When the fetal length became > 70 cm, serum levels in the fetus, umbilical cord and mothers, and E2 levels in umbilical cord increased synchronously (p < 0.05). These results showed increases in the number of preantral follicles in the Antarctic minke whale fetal ovary along with fetal growth during the early gestation period. These findings suggest that the change in preantral follicles was associated with changes in the concentration of steroids in early gestation periods. The changes in steroid concentrations in the fetal and umbilical cord blood and the increased number of preantral follicles were coincident at around 70 cm in fetal length, whereas the growth and differentiation of primordial and primary follicles appeared to be independent of FSH and LH.
Department of Food Production Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan.
Yuki
Y
Muranishi
Motoki
M
Sasaki
Kengo
K
Hayashi
Norihito
N
Abe
Takuma
T
Fujihira
Hajime
H
Ishikawa
Seiji
S
Ohsumi
Aiko
A
Miyamoto
Yutaka
Y
Fukui
D000735:Androstenedione / Q000097:blood / Q000378:metabolism; D000818:Animals; D000864:Antarctic Regions; D004958:Estradiol / Q000097:blood / Q000378:metabolism; D005260:Female; D005312:Fetal Blood / Q000378:metabolism; D005318:Fetal Heart / Q000378:metabolism; D005640:Follicle Stimulating Hormone / Q000097:blood / Q000378:metabolism; D005865:Gestational Age; D006728:Hormones / Q000097:blood* / Q000378:metabolism; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism; D006080:Ovarian Follicle / Q000196:embryology*; D011247:Pregnancy; D011374:Progesterone / Q000097:blood / Q000378:metabolism; D014907:Whales / Q000097:blood* / Q000196:embryology* / Q000378:metabolism
D006728:Hormones; D000735:Androstenedione; D011374:Progesterone; D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone