Kawasaki disease in central area of Northeast Thailand.
Kawasaki disease (KD) is a leading cause of acquired heart disease of childhood. The authors retrospectively reviewed cases of KD in major referral centers of central Northeast Thailand from July 1991 to June 2003. Seventy-three episodes occurring in 72 patients were diagnosed with KD by the American Heart Association criteria with a mean age of presentation of 27 +/- 19 months. The annual incidence was 2.2 per 100,000 children < 5 years of age. Coronary artery abnormalities (CAA) were found in 15 (20.5%) children. Nine patients (18%) who were diagnosed before 10 days were not treated with intravenous immunoglobulin (IVIG). Two (13%) of the 15 patients still had coronary lesions at the end of the follow-up period of 35.5 +/- 13.4 months. Index of suspicious should be maintained in children who had clinical signs of KD for early diagnosis and prompt treatment with IVIG.
Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Thailand. manat@kku.ac.th
Manat
M
Panamonta
Arnkisa
A
Chaikitpinyo
Kritvikrom
K
Durongpisitkul
Supattra
S
Somchit
Setthasiri
S
Petcharatana
Yuttapong
Y
Wongswadiwat
Pope
P
Kosalaraksa
Pagakrong
P
Lumbiganon
D002675:Child, Preschool; D003231:Conjunctivitis / Q000209:etiology; D003327:Coronary Disease / Q000209:etiology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D015994:Incidence; D007223:Infant; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D013785:Thailand / Q000453:epidemiology
D016756:Immunoglobulins, Intravenous