Fatal cerebral infarctions in diabetic ketoacidosis in a child with previously unknown heterozygosity for factor V Leiden deficiency.
An 11-year-old boy with poorly controlled diabetes had sudden collapse after the development of lower extremity deep venous thrombosis, with fatal cerebral infarctions. He was heterozygous for factor V Leiden deficiency. This case emphasizes the value of cranial imaging after initial resuscitative treatment of neurologic collapse in diabetic ketoacidosis.
Rosenbloom
Arlan L
AL
Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA. rosenal@peds.ufl.edu <rosenal@peds.ufl.edu>
D002544:Cerebral Infarction / Q000209:etiology*; D002648:Child; D016883:Diabetic Ketoacidosis / Q000150:complications*; D005165:Factor V / Q000235:genetics*; D005166:Factor V Deficiency / Q000150:complications*; D017809:Fatal Outcome; D006801:Humans; D008297:Male
C095381:factor V Leiden; D005165:Factor V