[Effectiveness of artificial pneumothorax in the treatment of patients with pulmonary tuberculosis with multiple drug-resistant Mycobacteria].
The efficiency of treatment was compared in 2 groups of patients with destructive pulmonary tuberculosis and isolation of multidrug resistant Mycobacteria. In 43 patients of a study group, artificial pneumothorax (AP) was used during chemotherapy with reserve drugs while 43 patients of a control group received chemotherapy alone. AP was shown to be highly effective in treating patients with destructive pulmonary tuberculosis who isolated multidrug resistant Mycobacteria. Moreover, by the end of 12-month therapy, AP in combination with chemotherapy ensured cessation of bacterial isolation in 88.7% and cavernous closure in the lung in 86.8%, which was almost twice higher than that with therapy with reserve antituberculous drugs.
Chukanov
V I
VI
Mishin
V Iu
VIu
Sigaev
A T
AT
Vasil'eva
I A
IA
Osadchaia
O A
OA
Perfil'ev
A V
AV
Naumova
A N
AN
Bagdasarian
T R
TR
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D024901:Drug Resistance, Multiple, Bacterial; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011031:Pneumothorax, Artificial / Q000379:methods*; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy / Q000628:therapy*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000628:therapy*
D000995:Antitubercular Agents