The treatment of high and intermediate anorectal malformations: one stage or three procedures?
OBJECTIVE
The aim of this study was to examine the safety, feasibility, and the long-term outcome of complete 1-stage repair of high and intermediate anorectal malformation using posterior sagittal anorectoplasty (PSARP) in a neonate.


METHODS
One hundred thirteen patients with high-type and intermediate-type anorectal malformations (ARM) underwent follow-up. Of 113 cases, 48 cases entailed a divided colostomy, definitive operation, and colostomy closure (group I); the other 65 patients underwent 1-stage PSARP (group II). Anorectal function was measured by the modified Wingspread scoring, including "excellent," "good," "fair," and "poor." In barium enema studies, anorectal angulation was judged as "clear," "unclear," and "not present," and leakage of barium was observed in the meantime. For anorectal manometric studies, anal resting pressure (ARP), anal squeezing pressure (ASP), and positive anorectal reflex (PAR) were measured.


RESULTS
In group I, the rate of excellent and good scores was 58.3% (28 of 48). In the barium enema examination, 85.4% (41 of 48) was clear and 14.6%(7 of 48) unclear or not present. The rate of barium leakage was 10.4% (5 of 48). In group II, the rate of excellent and good was 53.8% (35 of 65). Anorectal angulations were clear in 83.1% of patients (54 of 65). Barium leakage happened in 7.69% of patients (5 of 65). Early operative complications occurred in 56.3% (27 of 48) of patients in group I and 29.2% (19 of 65) in group II. The incidence of colostomy complications in group I was 39.6% (19 of 48). Soiling and constipation were the major complications after the PSARP operation. The respective rates of constipation in the 2 groups were 47.9% (23 of 48) and 44.6% (29 of 65), and the respective rates of soiling were 47.9% (23 of 48) and 50.8% (33 of 65). There was no significant difference in the mean ARP between the 2 groups.


CONCLUSIONS
The 1-stage PSARP procedure in the neonate not only achieves the same long-term outcome as the conventional PSARP procedure but also involves fewer short-term complications. Complete 1-stage repair using the PSARP to treat high-type and intermediate-type anorectal malformations is safe and feasible.
Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Guochang
G
Liu
Jiyan
J
Yuan
Jinmei
J
Geng
Chunhua
C
Wang
Tuanguang
T
Li
D001003:Anal Canal / Q000002:abnormalities* / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D003125:Colostomy / Q000009:adverse effects / Q000379:methods; D003248:Constipation / Q000209:etiology; D013505:Digestive System Surgical Procedures / Q000009:adverse effects* / Q000379:methods*; D004311:Double-Blind Method; D005240:Feasibility Studies; D005242:Fecal Incontinence / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008365:Manometry; D012005:Rectal Prolapse / Q000209:etiology; D012006:Rectovaginal Fistula / Q000601:surgery; D012007:Rectum / Q000002:abnormalities* / Q000601:surgery*; D012086:Reoperation; D013529:Surgical Wound Dehiscence / Q000209:etiology; D013530:Surgical Wound Infection / Q000209:etiology; D016896:Treatment Outcome