Nanocrystalline hydroxyapatite-polyaspartate composites.
The direct synthesis of hydroxyapatite-poly-L-aspartic acid (HA-PASP) nanocrystals has been carried out in presence of increasing amounts of PASP in solution up to 56 mmol/l. WAXS, TEM, TGA, IR and chemical analyses were used to characterize the structure, morphology and composition of the products. PASP is quantitatively incorporated into HA crystals, provoking a reduction of the coherent length of the crystalline domains. Furthermore, composite crystals display a greater length/width ratio with respect to the control HA crystals, and show a remarkable trend towards aggregation. The broadening of the X-ray diffraction reflections indicate a reduction of the coherent length along the long dimension 002 and the cross section 310 of the apatite crystals. The comparison between the morphological and structural data allows to suggest a specific interaction between PASP and HA structure.
Dipartimento di Chimica "G. Ciamician" and ISOF-CNR, via Selmi 2, 40126 Bologna, Italy. adriana.bigi@unibo.it
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Bigi
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Boanini
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Gazzano
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Rubini
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Torricelli
D001672:Biocompatible Materials / Q000737:chemistry*; D003460:Crystallization / Q000379:methods*; D017886:Durapatite / Q000737:chemistry*; D008420:Manufactured Materials / Q000032:analysis; D008422:Materials Testing; D008968:Molecular Conformation; D049329:Nanostructures / Q000737:chemistry*; D010316:Particle Size; D010455:Peptides / Q000737:chemistry*
D001672:Biocompatible Materials; D010455:Peptides; C017645:polyaspartate; D017886:Durapatite