Sustained-release devices in inner ear medical therapy.
Inner ear medical therapy has been gaining increasing popularity during the last 2 decades. Despite the increased use of this therapy,basic questions regarding this type of treatment have not been answered. The authors have used a variety of sustained-release devices in the laboratory to begin to answer some of these basic questions. This article discusses the results of this work and the application and use of sustained-release devices in patients.
The Department of Defense Spatial Orientation Center, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA 93134, USA. mehoffer@nmcsd.med.navy.mil
Michael E
ME
Hoffer
Ben J
BJ
Balough
Kim R
KR
Gottshall
Keith
K
Allen
Peter
P
Weisskopf
Derin
D
Wester
Cary
C
Balaban
D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D003692:Delayed-Action Preparations; D016503:Drug Delivery Systems / Q000295:instrumentation*; D005839:Gentamicins / Q000008:administration & dosage*; D006801:Humans; D008575:Meniere Disease / Q000188:drug therapy; D014432:Tympanic Membrane
D000900:Anti-Bacterial Agents; D003692:Delayed-Action Preparations; D005839:Gentamicins