Lymphoproliferative disorders in paediatric rheumatic diseases. A report of two cases.
Lymphoproliferative disorders (LPD) are reported with a much lower frequency in children with rheumatic diseases than in their adult counterparts. We describe 2 patients who developed a lymphoma during the course of the disease. The first is a 16-year-old girl diagnosed with systemic juvenile idiopathic arthritis 6 years before who developed a mucosa-associated lymphoid tissue (MALT) lymphoma. The second report involves a boy diagnosed with systemic lupus erythematosus at 9 years of age who developed a Hodgkin's lymphoma 9 years after the disease onset. In spite of the low frequency of LPD in children with rheumatic diseases, these processes do occur.
Paediatric Rheumatology Unit, University Hospital La Paz, Madrid, Spain. reumaped.hulp@salud.madrid.org
R
R
Merino
J
J
de Inocencio
P
P
García-Miguel
J
J
García-Consuegra
D001171:Arthritis, Juvenile / Q000150:complications*; D002648:Child; D005260:Female; D006689:Hodgkin Disease / Q000209:etiology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000209:etiology*; D008297:Male; D010307:Parotid Neoplasms / Q000209:etiology*