Endometrial endotoxin, assisted reproductive technology, and preterm birth.
The failure of antibiotic prophylaxis to reduce preterm birth in women at risk and the increased rate of preterm birth in singleton pregnancy after ART may have a common explanation: persistent bacterial endotoxin in the endometrium, reported by Kamiyama et al. as an explanation for reduced fertility.
Iams
Jay D
JD
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, The Ohio State University, Columbus, Ohio 43210-1228, USA.
D019072:Antibiotic Prophylaxis; D004731:Endotoxins / Q000378:metabolism*; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D007246:Infertility / Q000382:microbiology*; D007752:Obstetric Labor, Premature / Q000382:microbiology; D011247:Pregnancy; D047928:Premature Birth / Q000382:microbiology*; D027724:Reproductive Techniques, Assisted
D004731:Endotoxins