Collagen fibers an important entity in skin tissues remodeling.
Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM) evaluation were carried out in the in vivo skin construct using fibrin as biomaterial. To investigate its progressive remodeling, nude mice were grafted and the Extracellular Matrix (ECM) components were studied at four and eight weeks post-grafting. It was discovered that by 4 weeks of remodeling the skin construct acquired its native structure.
Norhayati
M M
MM
Institute of Bioscience, Universiti Putra Malaysia.
Mazlyzam
A L
AL
Asmah
R
R
Fuzina
H
H
Aminuddin
B S
BS
Ruszymah
B H I
BH
Fauziah
O
O
D000818:Animals; D003094:Collagen / Q000502:physiology*; D005109:Extracellular Matrix / Q000473:pathology; D005347:Fibroblasts / Q000473:pathology; D006801:Humans; D051379:Mice; D008819:Mice, Nude; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D012038:Regeneration / Q000502:physiology*; D012867:Skin / Q000473:pathology*; D016038:Skin Transplantation / Q000473:pathology; D023822:Tissue Engineering
D003094:Collagen