Genomic and proteomic adaptations to growth at high temperature.
Most positively selected mutations cause changes in metabolism, resulting in a better-adapted phenotype. But as well as acting on the information content of genes, natural selection may also act directly on nucleic acid and protein molecules. We review the evidence for direct temperature-dependent natural selection acting on genomes, transcriptomes and proteomes.
Department of Biology, Concordia University, 7141 Sherbrooke Street, Montreal, Quebec, H4B 1R6, Canada. dhickey@alcor.concordia.ca
Donal A
DA
Hickey
Gregory A C
GA
Singer
D000222:Adaptation, Physiological / Q000235:genetics*; D001482:Base Composition; D003062:Codon / Q000235:genetics; D004247:DNA / Q000235:genetics; D005057:Eukaryotic Cells / Q000378:metabolism; D019143:Evolution, Molecular; D016678:Genome; D023281:Genomics; D006358:Hot Temperature; D014176:Protein Biosynthesis / Q000235:genetics; D020543:Proteome / Q000235:genetics* / Q000378:metabolism*; D040901:Proteomics; D012313:RNA / Q000235:genetics; D012641:Selection, Genetic; D014158:Transcription, Genetic / Q000235:genetics
D003062:Codon; D020543:Proteome; D012313:RNA; D004247:DNA