Diastereoselective synthesis of cycloheptadienol derivatives by a formal [5+2] carbocyclization reaction of alpha,beta,gamma,delta-diunsaturated (methoxy)carbene complexes with methyl ketone lithium enolates.
Barluenga
José
J
Instituto Universitario de Química Organometálica "Enrique Moles", Unidad Asociada al CSIC, Universidad de Oviedo, Julián Clavería 8, 33006 Oviedo, Spain. barluenga@uniovi.es
Alonso
Jorge
J
Fañanás
Francisco J
FJ
Borge
Javier
J
García-Granda
Santiago
S
D018360:Crystallography, X-Ray; D003500:Cyclization; D003508:Cycloheptanes / Q000138:chemical synthesis*; D006838:Hydrocarbons; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry*; D008094:Lithium / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism
D003508:Cycloheptanes; D006838:Hydrocarbons; D007659:Ketones; D009942:Organometallic Compounds; C030011:carbene; D008094:Lithium; D008697:Methane