HIV and malaria: a lesson in immunology?
HIV is now common in many areas of Africa that are also highly endemic for malaria. In this article, Geoff Butcher summarizes the available data on the possible interaction o f HIV and malaria, and shows that the course of falciparum malaria is virtually unaffected by the presence of HIV. This raises significant questions for our understanding of immunity to the asexual blood stages of human malaria and the use of animal models in malaria research.
Butcher
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Department of Biology, Imperial College o f Science Technology and Medicine, Prince Consort Road, London, UK SW7 2BB.