The functional and immunological significance of some schistosome surface molecules.
The molecules discussed in this review include some of the leading vaccine candidates in schistosomiasis: the glutathione S-transferases, triose-phosphate isomerase, glyceraldehyde-3-phosphate dehydrogenase and the 23 and 25 kDa surface integral membrane proteins. Mark Wright, Kathy Davem and Graham Mitchell highlight the possible biological roles and immunological relevance of these molecules.
The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria 3050, Australia.
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