Presence of proboscipedia and caudal gene homologues in a bivalve mollusc.
Homeobox genes encode a family of transcription factors that have essential roles in regulating the development of eukaryotes. Although they have been extensively studied in different phyla, relatively little is known about homeoboxcontaining genes and their function in molluscs. In this study, we used a polymerase chain reaction to investigate homeobox genes in the bivalve mollusc Pecten maximus. Four different homeobox sequences were identified; two were homologues of the non-Hox cluster gene caudal and the two remaining sequences had a significant homology to the ANT-C gene Proboscipedia. These sequences represent the first cad and pb homologues isolated from a member of the class Bivalvia, phylum Mollusca.
Laboratorio de Biología Molecular y del Desarrollo, Departamento de Bioquímica y Biología Molecular, Instituto de Acuicultura, Universidad de Santiago de Compostela, 15782-Santiago de Compostela, Spain.
Pablo
P
Carpintero
Antonio Juan
AJ
Pazos
Marcelina
M
Abad
José Luis
JL
Sánchez
María de la Luz
Mde L
Pérez-Parallé
D000595:Amino Acid Sequence; D000818:Animals; D029721:Drosophila Proteins / Q000235:genetics; D018398:Homeodomain Proteins / Q000235:genetics*; D008969:Molecular Sequence Data; D008974:Mollusca / Q000235:genetics*; D010802:Phylogeny; D016415:Sequence Alignment; D017385:Sequence Homology; D014157:Transcription Factors / Q000235:genetics
D029721:Drosophila Proteins; D018398:Homeodomain Proteins; D014157:Transcription Factors; C084564:cad protein, Drosophila; C096658:pb protein, Drosophila