Intestinal mucus alters the ability of probiotic bacteria to bind aflatoxin B1 in vitro.
Several probiotics are known to bind aflatoxin B(1) (AFB(1)) to their surfaces and to adhere to intestinal mucus. In this study, preincubation of two probiotic preparations with either AFB(1) or mucus reduced the subsequent surface binding of mucus and AFB(1), respectively, in a strain-dependent manner.
Gratz
S
S
Department of Clinical Nutrition, University of Kuopio, Harjulantie 1, P.O. Box 1627, 70211 Kuopio, Finland.
Mykkänen
H
H
Ouwehand
A C
AC
Juvonen
R
R
Salminen
S
S
El-Nezami
H
H
D016604:Aflatoxin B1 / Q000378:metabolism* / Q000633:toxicity; D000818:Animals; D005506:Food Contamination; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000378:metabolism*; D007422:Intestines / Q000382:microbiology*; D007700:Kinetics; D007778:Lactobacillus / Q000378:metabolism; D009093:Mucus / Q000378:metabolism* / Q000382:microbiology*; D019936:Probiotics; D011424:Propionibacterium / Q000378:metabolism; D034421:Sus scrofa
D016604:Aflatoxin B1