Antiparasitic activity of an ivermectin and praziquantel combination paste in horses.
Modern anthelmintic use in horses has decreased the prevalence of the large strongyles, which has in turn shifted the focus of parasitologists to the pathogenic importance of the small strongyles, tapeworms, and other parasites. These studies show that a combination product containing ivermectin and praziquantel allowed efficacious treatment of horses for nematode, cestode, and bot infections. The use of this combination product may be of special benefit to horses that are mainly kept outdoors and on grazing pastures.
Marley
Sara E
SE
Merial Limited, Duluth, GA, USA.
Hutchens
Doug E
DE
Reinemeyer
Craig R
CR
Holste
John E
JE
Paul
Allan J
AJ
Rehbein
Steffen
S
D000284:Administration, Oral; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D000923:Anticestodal Agents / Q000627:therapeutic use; D000969:Antinematodal Agents / Q000627:therapeutic use; D002590:Cestode Infections / Q000188:drug therapy / Q000662:veterinary; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D006374:Helminthiasis, Animal / Q000188:drug therapy; D006734:Horse Diseases / Q000188:drug therapy* / Q000469:parasitology; D006736:Horses; D007559:Ivermectin / Q000627:therapeutic use*; D008297:Male; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary; D011223:Praziquantel / Q000627:therapeutic use*; D011897:Random Allocation; D013319:Strongyle Infections, Equine / Q000188:drug therapy*; D017183:Strongylida / Q000187:drug effects; D016896:Treatment Outcome
D000871:Anthelmintics; D000923:Anticestodal Agents; D000969:Antinematodal Agents; D011223:Praziquantel; D007559:Ivermectin