Inhibition of microsporidian spore germination.
Microsporidia are obligate intracellular parasites that are increasingly recognized as significant causes of disease in AIDS patients. Gordon Leitch, Govinda Visvesvara and Qing He here describe the deployment of the microsporidian spore infection apparatus, the polar filament, and show how this may be a useful site for chemotherapeutic interdiction of the infections caused by these parasites.
Leitch
G J
GJ
Department of Physiology, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Visvesvara
G S
GS
He
Q
Q