Aza-Reformatsky-type reaction of alpha-iodomethyl ketone O-alkyl oximes promoted by titanium tetraiodide.
Titanium tetraiodide promotes an aza-Reformatsky-type reaction of alpha-iodomethyl ketone O-alkyl oximes with carbonyl compounds to give beta-hydroxy ketone O-alkyl oximes in good to high yields.
Department of Chemistry for Materials, Mie University, Tsu, Mie 514-8507, Japan. mshimizu@chem.mie-u.ac.jp.
Makoto
M
Shimizu
Tadahiro
T
Toyoda