Cardiac tissue engineering: regeneration of the wounded heart.
New solutions are needed to regenerate hearts damaged by myocardial infarction, to overcome bad prognosis of patients with heart failure, and to address the shortage of heart donors. In the past few years, cardiac tissue engineering has emerged as a new and ambitious approach that combines knowledge from material chemistry with cell biology and medicine. In this short review, we present an overview on the most promising materials and cell-therapy strategies used in the past few years for the regeneration of the wounded heart.
Zammaretti
Prisca
P
Institute for Biomedical Engineering, Swiss Federal Institute, Moussonstrasse, 18, 8044 Zurich.
Jaconi
Marisa
M
D000818:Animals; D001672:Biocompatible Materials; D017690:Cell Transplantation / Q000379:methods; D006321:Heart / Q000502:physiology; D006333:Heart Failure / Q000628:therapy*; D006801:Humans; D009203:Myocardial Infarction / Q000628:therapy*; D012038:Regeneration; D023822:Tissue Engineering / Q000379:methods
D001672:Biocompatible Materials