Comparison of four demand oxygen delivery systems at rest and during exercise for chronic obstructive pulmonary disease.
OBJECTIVE
The aim of this study was to assess the performance of four demand oxygen delivery systems (DODS) in improving oxygenation and effort tolerance, at rest and during exercise, in chronic obstructive pulmonary disease (COPD) patients.


METHODS
Thirteen COPD patients were prospectively included. Four DODS (Oxiclip, Versatile, Venture and Impulse) were compared with continuous-flow oxygen (CFO). Nine of these patients performed 6-min walking tests on room air and on 3 l/min oxygen by DODS and CFO; Oxygen saturation, walking distance and the Borg dyspnea score were recorded.


RESULTS
With all four DODS devices arterial oxygenation was improved with lower oxygen flow rates than with CFO. Oxygen economy was best with Impulse, but at a cost of less satisfactory oxygenation. Exercise desaturation was similar with CFO, Oxiclip, Venture, and Impulse but significantly higher with Versatile (P < 0.05). Borg dyspnea scores were similar with CFO, Oxiclip, Venture, and Versatile but worse with Impulse (P < 0.05). There was no significant difference in walking distances.


CONCLUSIONS
All four DODS improved oxygen saturation and saved oxygen. However, performance was better with the two devices (Oxiclip and Venture) that deliver a bolus of oxygen at inspiration onset.
Fuhrman
C
C
Service de Pneumologie, Centre Hospitalier Intercommunal de Créteil, Créteil, France.
Chouaid
C
C
Herigault
R
R
Housset
B
B
Adnot
S
S
D015444:Exercise / Q000502:physiology*; D017079:Exercise Tolerance; D005260:Female; D005541:Forced Expiratory Volume / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000008:administration & dosage* / Q000097:blood; D010102:Oxygen Inhalation Therapy / Q000295:instrumentation*; D010313:Partial Pressure; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology / Q000628:therapy*; D014797:Vital Capacity / Q000502:physiology
D010100:Oxygen