Do elevated levels of eicosanoids play a role in head and neck cancer recurrence and metastasis? Implications for prevention and treatment.
Department of Pathology, Arizona Cancer Center, University of Arizona, College of Medicine, Tucson, Arizona, USA.
Durga P
DP
Cherukuri
Mark A
MA
Nelson
D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D051546:Cyclooxygenase 2; D015232:Dinoprostone / Q000096:biosynthesis / Q000494:pharmacology; D015777:Eicosanoids / Q000378:metabolism*; D015972:Gene Expression Regulation, Neoplastic; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D008565:Membrane Proteins; D009362:Neoplasm Metastasis / Q000235:genetics / Q000503:physiopathology; D009364:Neoplasm Recurrence, Local; D011451:Prostaglandin-Endoperoxide Synthases / Q000096:biosynthesis / Q000494:pharmacology*; D015854:Up-Regulation
D015777:Eicosanoids; D008565:Membrane Proteins; D051546:Cyclooxygenase 2; C496540:PTGS2 protein, human; D011451:Prostaglandin-Endoperoxide Synthases; D015232:Dinoprostone