Changes in cognitive function after neuronal cell transplantation for basal ganglia stroke.
Reported is the change in cognitive function after neuronal cell transplantation as a treatment for basal ganglia stroke. Nine subjects (two controls, seven transplants), all over 2 years post stroke, completed a comprehensive neuropsychological test battery prior to and 6 months after treatment. Four transplanted subjects who had strokes in the nondominant hemisphere showed marked improvement on the Rey Complex Figure, a test of visuospatial/constructional ability and nonverbal memory.
Stilley
C S
CS
Neurotransplantation Research Program and School of Nursing, University of Pittsburgh, PA, USA. css100@pitt.edu
Ryan
C M
CM
Kondziolka
D
D
Bender
A
A
DeCesare
S
S
Wechsler
L
L
D000368:Aged; D020144:Basal Ganglia Cerebrovascular Disease / Q000503:physiopathology / Q000523:psychology / Q000601:surgery*; D020520:Brain Infarction / Q000503:physiopathology / Q000523:psychology / Q000601:surgery*; D003071:Cognition; D004292:Dominance, Cerebral; D006801:Humans; D011939:Mental Recall; D008875:Middle Aged; D009474:Neurons / Q000637:transplantation*; D009483:Neuropsychological Tests; D016037:Single-Blind Method; D013238:Stereotaxic Techniques; D013647:Task Performance and Analysis