Transplantation from non heart beating donors in Newcastle upon Tyne.
Donor shortage has led transplant surgeons to reevaluate the concept of non heart beating donation. Organs from such donors are exposed to anoxia prior to harvesting and a portion of them will consequently present with delayed graft function. There is a need for dependable viability testing of organs from less than ideal NHBD donors and machine perfusion of kidneys provides such a tool. Our experience with own design machine perfusion device, studied parameters, perfusion solutions and outcomes is presented. Emphasis is placed on the incomparability of results obtained from different perfusion systems and the need to establish local criteria of kidney viability.
Asher
John
J
Renal and Liver Transplant Unit, Freeman Hospital, High Heaton, Newcastle upon Tyne, NE7 7DN. john.asher@btinternet.com
Wilson
Colin
C
Gok
Muhammed
M
Shenton
Brian K
BK
Stamp
Susan
S
Wong
Yew Toh
YT
Gupta
Ajay
A
Talbot
David
D
D004739:England; D006323:Heart Arrest; D006801:Humans; D009926:Organ Preservation; D016377:Organ Transplantation; D010477:Perfusion / Q000295:instrumentation / Q000379:methods; D014019:Tissue Donors; D014022:Tissue Survival