Treatment of Onchocerciasis with ivermectin in Central America.
The success o f ivermectin in controlling transmission of Onchocerca volvulus in Guatemala suggests a broader role for this drug than morbidity control alone. In this article Ed Cupp reviews recent findings from a three-year pilot study in that country which evaluated the effects of recurrent semiannual treatment on several important factors associated with the biology o f river blindness. These results illustrate the range o f beneficial effects that occur not only for this disease but for other parasitisms when this drug is administered at the community level.
Department of Veterinary Science, University of Arizona, Tucson, AZ 85721, USA.
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