Fatal cerebral infarctions in diabetic ketoacidosis in a child with previously unknown heterozygosity for factor V Leiden deficiency.
An 11-year-old boy with poorly controlled diabetes had sudden collapse after the development of lower extremity deep venous thrombosis, with fatal cerebral infarctions. He was heterozygous for factor V Leiden deficiency. This case emphasizes the value of cranial imaging after initial resuscitative treatment of neurologic collapse in diabetic ketoacidosis.
Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA. rosenal@peds.ufl.edu <rosenal@peds.ufl.edu>
Arlan L
AL
Rosenbloom
D002544:Cerebral Infarction / Q000209:etiology*; D002648:Child; D016883:Diabetic Ketoacidosis / Q000150:complications*; D005165:Factor V / Q000235:genetics*; D005166:Factor V Deficiency / Q000150:complications*; D017809:Fatal Outcome; D006801:Humans; D008297:Male
C095381:factor V Leiden; D005165:Factor V