Microscopic evaluation of the natural coral (Porites spp.) post-implantation in sheep femur.
The study was carried out with the aim to evaluate natural coral (Porites spp.) implanted in sheep femur microscopically. Twelve adult, male sheep were used in this study. The defect area was implanted with coral and monitored for up to 12 weeks. The sheep were euthanased at 2,4,8, and 12 weeks post-implantation. Microscopically, natural coral implanted into bone tissue have shown gradual resorption and progressively replaced by new bone. At 12 weeks post-implantation, the implanted site was almost completely surrounded by mature bone. The results showed that natural coral was found to be a biodegradable and osteo-conductive biomaterial, which acted as a scaffold for a direct osteoblastic apposition.
Fadilah
A
A
Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 UPM.
Zuki
A B Z
AB
Loqman
M Y
MY
Zamri-Saad
M
M
Al-Salihi
K A
KA
Norimah
Y
Y
Asnah
H
H
D020341:Absorbable Implants; D000818:Animals; D037421:Anthozoa; D018786:Bone Substitutes; D002119:Calcium Carbonate; D005269:Femur / Q000473:pathology*; D008297:Male; D010006:Osteoblasts / Q000473:pathology; D012756:Sheep
D018786:Bone Substitutes; D002119:Calcium Carbonate