Is a metallic stent useful for non resectable esophageal cancer?
A flexible nitinol stent was inserted to treat malignant stricture of the esophagus in 28 patients. Stenting was successful in all 28 patients, leading to an improved oral intake that was maintained for >80% of the survival period in 26 patients. Patients with tumors arising in the esophagus (n=24) were divided into two groups to compare complications and prognosis: patients who underwent stenting only (n=10); and patients who underwent stenting after radiochemotherapy (n=14). Fatal complications associated with stenting were seen in four patients (28.6%) who underwent stenting after radiochemotherapy and in one patient (10.0%) who underwent stenting only. Although survival was significantly longer for patients who underwent prior radiochemotherapy than for patients who did not, the incidence of fatal complications tended to be higher. No significant differences in background factors other than radiochemotherapy before stenting were observed between patients with fatal and non-fatal complications. Stenting was shown to represent a useful treatment for malignant stricture of the esophagus, as oral intake improved and was maintained for a long period of time in most patients. However, incidence of fatal complications was high among patients who underwent radiochemotherapy, and caution must be exercised due to the difficulty in predicting fatal complications.
Department of Oncological Science (Surgery 2), Oita University Faculty of Medicine, Oita, Japan.
Shinsuke
S
Wada
Tsuyoshi
T
Noguchi
Shinsuke
S
Takeno
Hatsuo
H
Moriyama
Tsuyoshi
T
Hashimoto
Yuzo
Y
Uchida
Katsunobu
K
Kawahara
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000497:Alloys; D002277:Carcinoma / Q000401:mortality / Q000556:secondary / Q000628:therapy*; D003680:Deglutition Disorders / Q000209:etiology / Q000601:surgery; D004938:Esophageal Neoplasms / Q000401:mortality / Q000556:secondary / Q000628:therapy*; D004945:Esophagoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015607:Stents / Q000009:adverse effects; D015996:Survival Rate; D016896:Treatment Outcome
D000497:Alloys; C013616:nitinol