The polyprotein allergens of nematodes.
Symptoms of infection with a number of parasitic nematodes may be associated with IgE antibody and associated immunopathologies. This has drawn attention to parasite allergens and provoked discussion on the wisdom of their inclusion in recombinant vaccines. Here, Larry McReynolds, Malcolm Kennedy and Murray Selkirk review work on a prominent set of allergens recently characterized in several nematode species.
McReynolds
L A
LA
Molecular Parasitology Division, New England Biolabs, 32 Tozer Road, Beverly, MA 019 15, USA.
Kennedy
M W
MW
Selkirk
M E
ME