[The long-term memory retrieval following kainic acid administration].
Effect of the neurotoxin kainic acid to the food-procuring task were studied in Wistar rats. A single injection of the acid in subconvulsive dose (8 mg/kg) impaired the task performance within some weeks but not immediately after the treatment. Higher doses of kainic acid (10 mg/kg) impaired the task performance within a few hours after treatment for up to 10 days. The treatment did not prevent rat's learning of a new task in the same experimental chamber. The revealed deficit in the long-term memory retrieval might be explained by specific effects of kainic acid upon the hippocampal system.
Arkhipov
V I
VI
Shevchenko
N A
NA
D000818:Animals; D005247:Feeding Behavior / Q000187:drug effects* / Q000523:psychology; D007608:Kainic Acid / Q000633:toxicity*; D008297:Male; D008568:Memory / Q000187:drug effects* / Q000502:physiology; D011939:Mental Recall / Q000187:drug effects* / Q000502:physiology; D009498:Neurotoxins / Q000633:toxicity; D051381:Rats
D009498:Neurotoxins; D007608:Kainic Acid