Emerging trends in infections among renal transplant recipients.
Outcomes following renal and simultaneous kidney-pancreas transplants have improved significantly due to better surgical techniques and improved modalities of antirejection therapy. However, infection remains a significant cause of morbidity and mortality. The use of new modalities of immunosuppression and routine use of antimicrobial prophylaxis has changed the pattern of infections post-transplantation. Cytomegalovirus remains a significant problem and BK virus has emerged as an important pathogen. New antimicrobial agents are now available to treat infection, however, antimicrobial resistance remains a concern.
Division of Infectious Diseases, Wayne State University School of Medicine, Detroit, MI, USA.
Nestor F
NF
Varon
George J
GJ
Alangaden
D000818:Animals; D006801:Humans; D007114:Immunization; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D007239:Infections / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000276:immunology; D009894:Opportunistic Infections / Q000188:drug therapy / Q000382:microbiology; D011183:Postoperative Complications / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control / Q000628:therapy*; D012306:Risk; D013530:Surgical Wound Infection / Q000188:drug therapy
D007166:Immunosuppressive Agents