Assessment of areas at increased risk for poliovirus circulation in Ecuador.
To assess areas at risk for poliovirus circulation in Ecuador, we first selected provinces at highest risk based on low immunization coverage with three doses of oral poliovirus vaccine, and a low number of reported cases of acute flaccid paralysis (AFP). Subsequently, we reviewed discharge data for the period 1996--2000 for diagnoses compatible with AFP in the only two national referral hospitals in Quito, and at least two main hospitals in each of the six selected provinces. Environmental samples from one or two cities/towns in each selected province were tested for poliovirus. Of the 14 identified AFP-compatible cases, 8 (57%) had been previously reported and investigated. We visited four out of the six unreported cases; none of those four had sequelae compatible with poliomyelitis. From the 14 environmental samples taken, we identified Sabin viruses in six of the samples; no vaccine-derived polioviruses were isolated. Using this methodology, we found no evidence of undetected poliovirus circulation in Ecuador.
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. gdayan@cdc.gov
Gustavo H
GH
Dayan
Rodrigo
R
Rodríguez
Jan
J
Vinjé
Nancy
N
Vásconez
Víctor
V
Cáceres
Nicole
N
Gregoricus
Mark
M
Sobsey
Mauricio
M
Landaverde
D004196:Disease Outbreaks / Q000517:prevention & control*; D004197:Disease Reservoirs; D004484:Ecuador / Q000453:epidemiology; D004784:Environmental Monitoring / Q000379:methods; D062665:Epidemiological Monitoring; D006801:Humans; D010351:Patient Discharge / Q000706:statistics & numerical data*; D011051:Poliomyelitis / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control* / Q000635:transmission / Q000821:virology; D017955:Poliovirus / Q000302:isolation & purification*; D011055:Poliovirus Vaccine, Oral; D011159:Population Surveillance / Q000379:methods*; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D014611:Vaccination / Q000706:statistics & numerical data
D011055:Poliovirus Vaccine, Oral