Thrombophilia and pregnancy complications.
The implications of currently available data on the association of gestational vascular complications with thrombophilia are presented in this consensus report. Screening is recommended for women with the following previous complications: fetal loss including three or more first trimester loss, two or more second trimester loss, or any stillbirth; early, severe or recurrent preeclampsia and severe intrauterine growth restriction. Maternal antithrombotic therapy is currently evaluated in women with thrombophilia and previous complications.
Brenner
Benjamin
B
Thrombosis and Hemostasis Unit, Department of Hematology, Rambam Medical Center, PO Box 9602, Hiafa 31096, Israel. b-Brenner@rambam.health.gov.il
Grabowski
Eric F
EF
Hellgren
Margaretta
M
Kenet
Gili
G
Massicotte
Patricia
P
Manco-Johnson
Marilyn
M
Mathew
Prasad
P
Muntean
Wolfgang
W
Schlegel
Nicole
N
Nowak-Göttl
Ulrike
U
D000026:Abortion, Habitual / Q000097:blood / Q000209:etiology; D000328:Adult; D000075202:Contraindications; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy / Q000209:etiology*; D011256:Pregnancy Outcome; D019851:Thrombophilia / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
D005343:Fibrinolytic Agents