A case of Schönlein-Henoch-purpura: an immunopathological study.
A case of Schonlein-Henoch-purpura is presented. The immunofluorescent study of skin lesions of the patient showed granular deposits of IgA and C3 in the blood vessel walls perivascular deposits of plasminogen and diffuse localization of fibrin and fibrinogen in the upper dermis. Complement activation via the alternative pathway through IgA, C3 and plasminogen deposits was suggested.
Department of Dermatology, Kawasaki Medical School, Kurashiki 701-01, Japan.
M
M
Namba
M
M
Kohda
M
M
Gotoh
S
S
Nakagawa
H
H
Ueki
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001707:Biopsy, Needle; D003176:Complement C3 / Q000032:analysis / Q000276:immunology*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D011695:IgA Vasculitis / Q000175:diagnosis / Q000276:immunology* / Q000473:pathology*; D007070:Immunoglobulin A / Q000032:analysis / Q000276:immunology*; D007150:Immunohistochemistry; D007564:Japan; D011379:Prognosis; D018570:Risk Assessment; D012720:Severity of Illness Index
D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D003176:Complement C3; D007070:Immunoglobulin A