[An algorithm of respiratory management in the complex treatment and prevention of acute pulmonary lesions in patients with impairments of the central nervous system].
The authors elaborated an algorithm of respiratory management (RM) based on the correlation of RM parameters with the actual and proper thoracopulmonary compliance (C). The algorithm was tested on 42 patients with affections of the central nervous system (CNS) due to severe craniocerebral trauma, spinal trauma, cerebral stroke and multitrauma. Thirty-nine case-matching patients where in the control group--the routine RM algorithm was used for them. Mean pressure in the respiratory paths (Pmean, C, PaO2/FiO2 and rSO2 readings by the Glasgow coma scale, cerebral perfusion pressure, and consumption of sedatives, muscle relaxants and vasopressins as well as frequency rate of acute pulmonary lesions (APL) were registered. The RM algorithm provided for a more effective prevention and treatment of APL versus the routine RM--it cut, 3-fold, the remote APL. With the above RM algorithm, the need in sedatives, muscle relaxants and vasopressins went down from day 2. Positive trends in the neurological status as well as normalized rSO2 were observed earlier versus the controls. Finally, its use ensured a more favorable treatment outcome.
Chechenin
M G
MG
Martynenkov
V Ia
VIa
Denisov
E N
EN
Lukashev
K V
KV
D000328:Adult; D000465:Algorithms; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009125:Muscle Relaxants, Central / Q000627:therapeutic use; D012128:Respiratory Distress Syndrome / Q000188:drug therapy* / Q000209:etiology; D020196:Trauma, Nervous System / Q000150:complications*; D014667:Vasopressins / Q000627:therapeutic use
D006993:Hypnotics and Sedatives; D009125:Muscle Relaxants, Central; D014667:Vasopressins