Calcium and salinity sensing by the thick ascending limb: a journey from mammals to fish and back again.
The roles of the CaSR in endocrine, epithelial, CNS, and other cells have been reviewed previously [17-19, 20, 27-30, 31-33]. This brief review focuses on the roles of the CaSR in the thick ascending limb of Henle (TAL), and is written in honor of my mentor and long-term friend and colleague, Thomas E. Andreoli, on the occasion of his retirement. My early studies of TAL function with Tom Andreoli were the inspiration for this work.
Department of Cellular and Molecular Physiology, Yale University School of Medicine, 333 Cedar Street, SHM B147, P.O. Box 208026, SA115 New Haven, CT 06525-8026 , USA. steven.hebert@yale.edu
Steven C
SC
Hebert
D000818:Animals; D001693:Biological Transport, Active; D002118:Calcium / Q000097:blood; D005399:Fishes; D006801:Humans; D007686:Kidney Tubules, Distal / Q000502:physiology*; D008138:Loop of Henle / Q000502:physiology*; D044169:Receptors, Calcium-Sensing / Q000502:physiology*; D012964:Sodium / Q000378:metabolism
D044169:Receptors, Calcium-Sensing; D012964:Sodium; D002118:Calcium