[Impact of extra waters on immunosystem in mice].
OBJECTIVE
To study impact of extra waters on immunosystem in mice-alkaline ionized water, mineral-ecology water, activated water, and pure water.


METHODS
According to Function Assessment and Experiment for Function Food, 1996, the ratio of spain and body weight, the ratio of thymus and body weight, the delayed type hypersensitivity (DTH), the phagocytosing functions by cock RBC, the plaque forming cell (PFC) and HC50 testing were assessment with 120 male Balb/c mice of 17.8 - 23.3 g (group I), the mice were divided into four group, and drank daily the four kinds of waters respectively until 50 days. The lymph cell transformation by ConA and NK cell activity were assessment with other l20 male Balb/c mice of 17.8 - 23.3 g (group II), the mice were divided into four group and drank daily the four kinds of waters respectively until 50 days. The phagocytosing functions by carbon powder were assessment with other 120 female Balb/c mice of 16.7 - 22.0 g (group III) were divided into four group and drank daily the four kinds of waters respectively until 50 days. The data were statisticed by Stata soft.


RESULTS
Other three waters compared with the pure water: (1) Alkaline ionized water and activated water can alleviate the body weight increase of male Balb/c mouse (P < 0.01 & P < 0.05), but alkaline ionized water, mineral-ecology water, activated water don't impact on the female Balb/c mouse body weight (P > 0.05). (2) Activated water can remarkably increase the ratio of thymus and body weight (P < 0.05), and increase the phagocytosing ability by cock RBC (P < 0.01), and increase the NK cell activity (P < 0.01). (3) The three extra waters don't impact on other items for the Balh/c mouce.


CONCLUSIONS
The study must be continued to impact on immunosystem in mice for extra waters.
Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Yepeng
Y
Li
Chunhui
C
Han
Yanjun
Y
Li
Yuwei
Y
Li
Xi
X
Zhao
Kai
K
Zhong
Tingjun
T
Chen
Ming
M
Zhang
Fucheng
F
Fan
Yong
Y
Tao
Rong
R
Ji
D000818:Animals; D007107:Immune System / Q000187:drug effects* / Q000276:immunology; D007694:Killer Cells, Natural / Q000276:immunology; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010587:Phagocytosis / Q000187:drug effects; D014867:Water; D015430:Weight Gain / Q000187:drug effects
D014867:Water