The involvement of hemozoin toxicity in depression of cellular immunity.
Human monocyte-derived macrophages are severely impaired after ingestion of isolated malaria pigment (hemozoin) or hemozoin-containing red blood cells'. In this brief review, Franco Turrini, Evelin Schwarzer and Poolo Arese discuss possible pothophysiologicol consequences, outline unresolved problems and provide an outlook for future research.
Turrini
F
F
Department of Genetics Biology and Medical Chemistry, University of Torino Medical School, Torino, Italy.
Schwarzer
E
E
Arese
P
P