Cytoplasmic crystalline inclusions in a anaplastic oligoastrocytoma.
A 41-year-old male presented with an ill-demarcated mass involving the left fronto-temporal lobe and the basal ganglia. Light microscopically the tumor was diagnosed as an anaplastic oligoastrocytoma. Electron microscopy revealed several cytoplasmic crystalline inclusions in tumor cells of oligodendroglial lineage. No crystalline inclusions were membrane bound. The morphologic features with unique ultrastructural findings are presented.
Kim
Min-Kyung
MK
Department of Pathology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea. mkgene@ilsanpaik.ac.kr
Joo
Mee
M
Kim
Hanseong
H
Park
Sung-Hye
SH
Chi
Je G
JG
D000328:Adult; D001254:Astrocytoma / Q000737:chemistry / Q000601:surgery / Q000648:ultrastructure*; D014408:Biomarkers, Tumor / Q000032:analysis; D001932:Brain Neoplasms / Q000737:chemistry / Q000601:surgery / Q000648:ultrastructure*; D003460:Crystallization; D006801:Humans; D007150:Immunohistochemistry; D002479:Inclusion Bodies / Q000648:ultrastructure*; D008279:Magnetic Resonance Imaging; D008297:Male; D046529:Microscopy, Electron, Transmission
D014408:Biomarkers, Tumor