[Genotypes of Candida dubliniensis in clinical isolates].
Amplification of specific sequences of the ITS1 and ITS2 regions and the intervening 5.8S rRNA gene has lead to the identification of four separate genotypes in Candida dubliniensis. Using primers specific for each genotype, we have studied the prevalence of these genotypes among 68 clinical isolates, mostly from Spanish patients infected by HIV. The majority of the isolates tested belonged to genotype 1 (97%), while only one isolate each from genotypes 2 (1.5%) and 3 (1.5%) were detected in the oral cavity of two patients with HIV infection.
Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y odontología, Universidad del País Vasco, Bilbao, Spain.
Sonia
S
Brena
María del Carmen
Mdel C
Rubio
Ricardo
R
Salesa
Isabel
I
Iglesias
Joaquina
J
Gil
Antonio
A
Rezusta
María Dolores
MD
Moragues
José
J
Pontón
D002175:Candida / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D005838:Genotype; D006801:Humans