Development of a 30-week-pregnant female tomographic model from computed tomography (CT) images for Monte Carlo organ dose calculations.
Assessment of radiation dose and risk to a pregnant woman and her fetus is an important task in radiation protection. Although tomographic models for male and female patients of different ages have been developed using medical images, such models for pregnant women had not been developed to date. This paper reports the construction of a partial-body model of a pregnant woman from a set of computed tomography (CT) images. The patient was 30 weeks into pregnancy, and the CT scan covered the portion of the body from above liver to below pubic symphysis in 70 slices. The thickness for each slice is 7 mm, and the image resolution is 512x512 pixels in a 48 cm x 48 cm field; thus, the voxel size is 6.15 mm3. The images were segmented to identify 34 major internal organs and tissues considered sensitive to radiation. Even though the masses are noticeably different from other models, the three-dimensional visualization verified the segmentation and its suitability for Monte Carlo calculations. The model has been implemented into a Monte Carlo code, EGS4-VLSI (very large segmented images), for the calculations of radiation dose to a pregnant woman. The specific absorbed fraction (SAF) results for internal photons were compared with those from a stylized model. Small and large differences were found, and the differences can be explained by mass differences and by the relative geometry differences between the source and the target organs. The research provides the radiation dosimetry community with the first voxelized tomographic model of a pregnant woman, opening the door to future dosimetry studies.
Nuclear Engineering and Engineering Physics Program, Rensselaer Polytechnic Institute, Troy, New York 12180, USA.
Chengyu
C
Shi
X George
XG
Xu
D001822:Body Burden; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods / Q000592:standards; D008954:Models, Biological; D015233:Models, Statistical; D009010:Monte Carlo Method; D009928:Organ Specificity; D011247:Pregnancy / Q000502:physiology* / Q000528:radiation effects; D011261:Pregnancy Trimester, First / Q000502:physiology*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods* / Q000592:standards; D011874:Radiometry / Q000379:methods* / Q000592:standards; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods* / Q000592:standards; D012062:Relative Biological Effectiveness; D014057:Tomography, X-Ray Computed / Q000379:methods*