[Study on analysis of thioglycolic acid in cosmetics by ion chromatography].
OBJECTIVE
An analytical method of determinating thioglycolic acid in cosmetics by ion-exchange chromatography suppressed conductivity detection has been developed.


METHODS
A high capacity anion exchange column, IonPacAS11-HC column was used. 25mmol/L NaOH + 1% methanol was used as eluent, and the flow rate was set up at 0.85ml/min. Samples were pretreated by extraction with CHCl3 to remove some organic substance, and then upper clean liquid was injected.


RESULTS
The influence of samples' pH, coexist anion and the concentration of methanol in eluent on determination was discussed. The method enjoyed a wide linear range and good precision. The detection limit was 2.3mg/kg. The average recoveries were 91.5% - 10.0%, and the relative standard deviation (RSD%) was less 0.941.


CONCLUSIONS
The results showed that the method was simple, accurate and might be good for application.
Center of Disease Control and Prevention of Guangdong Province, Guangzhou 510300, China.
Zhixiong
Z
Zhong
Da'an
D
Du
Chunsui
C
Liang
Jing
J
Yao
D002852:Chromatography, Ion Exchange; D003358:Cosmetics / Q000737:chemistry*; D013864:Thioglycolates / Q000032:analysis*
D003358:Cosmetics; D013864:Thioglycolates