A pathophysiological approach to antiretroviral therapy.
A discussion of the pathophysiology of HIV infection is important not only to understand both routine and novel therapeutic approaches, but also to appreciate the challenges of long-term control and viral eradication. This article will first briefly review certain pathophysiologic principles of HIV infection that have particular therapeutic implications, and then discuss general tenets of antiretroviral therapy, followed by new developments in the field.
Walter Reed Army Medical Center, Washington, DC, USA. emillesho@yahoo.com.
Emil
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Lesho
D000818:Animals; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods*; D003713:Dendritic Cells / Q000276:immunology; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy* / Q000276:immunology / Q000503:physiopathology*; D015497:HIV-1 / Q000235:genetics / Q000276:immunology; D006801:Humans; D011247:Pregnancy; D015728:Receptors, HIV / Q000187:drug effects; D019562:Viral Load
D015728:Receptors, HIV