Lymphoproliferative disorders in paediatric rheumatic diseases. A report of two cases.
Lymphoproliferative disorders (LPD) are reported with a much lower frequency in children with rheumatic diseases than in their adult counterparts. We describe 2 patients who developed a lymphoma during the course of the disease. The first is a 16-year-old girl diagnosed with systemic juvenile idiopathic arthritis 6 years before who developed a mucosa-associated lymphoid tissue (MALT) lymphoma. The second report involves a boy diagnosed with systemic lupus erythematosus at 9 years of age who developed a Hodgkin's lymphoma 9 years after the disease onset. In spite of the low frequency of LPD in children with rheumatic diseases, these processes do occur.
Merino
R
R
Paediatric Rheumatology Unit, University Hospital La Paz, Madrid, Spain. reumaped.hulp@salud.madrid.org
de Inocencio
J
J
García-Miguel
P
P
García-Consuegra
J
J
D001171:Arthritis, Juvenile / Q000150:complications*; D002648:Child; D005260:Female; D006689:Hodgkin Disease / Q000209:etiology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000209:etiology*; D008297:Male; D010307:Parotid Neoplasms / Q000209:etiology*