Bovine somatotropin and rumen-undegradable protein effects in prepubertal dairy heifers: effects on body composition and organ and tissue weights.
The objectives of this study were to determine the effect of recombinant bovine somatotropin (bST) and added dietary rumen undegradable protein (RUP) on organ and tissue weights and body composition in growing dairy heifers. Thirty-two Holstein heifers were in the experiment, 8 killed initially at 3 mo of age, with the remaining 24 Holstein heifers randomly assigned to treatments (n = 6) consisting of 0.1 mg/kg of body weight per day of bST and 2% added dietary RUP (dry matter basis) applied in a 2 x2 factorial design. A total of 6 heifers per treatment group (3 each at 5 and 10 mo of age), were slaughtered to determine body composition and organ masses. Feed intake measured from group intakes were increased by 0.25 and 0.35 kg/d with bST and RUP, respectively. Administration of bST tended to increase the weights of visceral organs including heart, kidney, and spleen by 16, 16, and 38%, respectively. At 10 mo of age, there was a trend for increased empty body weights (EBW) and non-carcass components for heifers treated with bST, but there were no effects of RUP. Body components and organ weights, expressed as a percentage of BW were not affected by RUP or bST. Somatotropin increased ash weight at 10 mo without affecting amounts of protein, fat, and energy. Rates of ash deposition between 3 and 10 mo of age were increased 7 and 4 g/d by bST and RUP, respectively. There were no treatment effects on rates of body fat, protein, and energy deposition. Bovine somatotropin and RUP altered the metabolism of growing heifers in a manner that was consistent with increased rates of skeletal growth. This suggests that nutritional and endocrine manipulations could increase growth rates of skeletal tissues without increasing fat deposition in prepubertal dairy heifers.
Moallem
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U
Department of Animal and Avian Sciences, University of Maryland, College Park 20742, USA.
Dahl
G E
GE
Duffey
E K
EK
Capuco
A V
AV
Wood
D L
DL
McLeod
K R
KR
Baldwin
R L
RL
Erdman
R A
RA
D000375:Aging / Q000502:physiology; D000818:Animals; D001823:Body Composition / Q000187:drug effects*; D002417:Cattle / Q000254:growth & development / Q000378:metabolism*; D004044:Dietary Proteins / Q000008:administration & dosage* / Q000494:pharmacology; D002149:Energy Intake; D005260:Female; D013006:Growth Hormone / Q000008:administration & dosage* / Q000494:pharmacology; D009929:Organ Size / Q000187:drug effects*; D011897:Random Allocation; D012417:Rumen / Q000378:metabolism*; D015430:Weight Gain
D004044:Dietary Proteins; C073294:growth hormone, bovine; D013006:Growth Hormone