Gianotti-Crosti syndrome caused by acute hepatitis B virus genotype D infection.
A 12-year-old girl with Gianotti-Crosti syndrome caused by hepatitis B virus (HBV) infection was admitted due to eruption on her extremities. Laboratory findings revealed elevation of transaminase, positivity for HB surface antigen (HBsAg), and an IgM type anti-HB core. The eruption and level of transaminase improved, and HBsAg became negative within 2 months of onset. Analysis of the virus revealed it to be genotype D with a genomic length of 3,182 bases and the HBsAg serotype was ayw3, which is very rare in Japan. The possible relationship between Gianotti-Crosti syndrome and HBV genotype D infection is discussed.
Michitaka
Kojiro
K
Endoscopy Center, Ehime University School of Medicine, Shigenobucho, Onsen-gun, Ehime 791-0295.
Horiike
Norio
N
Chen
Yan
Y
Duong
Tran Nhu
TN
Konishi
Ichiro
I
Mashiba
Toshie
T
Tokumoto
Yoshio
Y
Hiasa
Yoichi
Y
Tanaka
Yasuhito
Y
Mizokami
Masashi
M
Onji
Morikazu
M
D000169:Acrodermatitis / Q000235:genetics / Q000821:virology*; D000208:Acute Disease; D002648:Child; D005260:Female; D005838:Genotype; D006509:Hepatitis B / Q000150:complications / Q000235:genetics*; D006515:Hepatitis B virus / Q000235:genetics*; D006801:Humans