Hypothalamic control of body temperature: insights from the past.
This essay looks at the historical significance of three APS classic papers that are freely available online: Hammel HT, Hardy JD, and Fusco MM. Thermoregulatory responses to hypothalamic cooling in unanesthetized dogs. Am J Physiol 198: 481-486, 1960 (http://ajplegacy.physiology.org/cgi/reprint/198/3/481). Hammel HT, Jackson DC, Stolwijk JAJ, Hardy JD, and Stromme SB. Temperature regulation by hypothalamic proportional control with an adjustable set point. J Appl Physiol 18: 1146-1154, 1963 (http://jap.physiology.org/cgi/reprint/18/6/1146). Hellstrom B and Hammel HT. Some characteristics of temperature regulation in the unanesthetized dog. Am J Physiol 213: 547-556, 1967 (http://ajplegacy.physiology.org/cgi/reprint/213/2/547).
Gary W
GW
Mack
D000818:Animals; D001833:Body Temperature Regulation / Q000502:physiology*; D004285:Dogs; D049673:History, 20th Century; D007031:Hypothalamus / Q000502:physiology*; D010827:Physiology / Q000266:history*; D011301:Preoptic Area / Q000502:physiology