Effect of elevated admission serum creatinine and its worsening on outcome in hospitalized patients with decompensated heart failure.
Renal insufficiency (RI), as represented by elevated serum creatinine (>1.5 mg/dl) on admission, is common and found in almost half of patients hospitalized with decompensated heart failure. This finding is associated with prolongation of length of stay and rate of rehospitalizations after discharge and also has an independent unfavorable effect on 6-month mortality. Similarly, an increase in serum creatinine (>0.5 mg/dl) in the hospital results in a significantly longer length of stay and has an independent effect on long-term mortality.
Heart Failure Program, Division of Cardiovascular Medicine, University of Southern California, Keck School of Medicine, Los Angeles, California 90033, USA.
Mohammed W
MW
Akhter
Doron
D
Aronson
Fahed
F
Bitar
Salman
S
Khan
Harpreet
H
Singh
Rajinder P
RP
Singh
Andrew J
AJ
Burger
Uri
U
Elkayam
D000368:Aged; D015415:Biomarkers / Q000097:blood; D001794:Blood Pressure / Q000502:physiology; D003404:Creatinine / Q000097:blood*; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000097:blood* / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007668:Kidney / Q000378:metabolism / Q000503:physiopathology; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010343:Patient Admission; D011237:Predictive Value of Tests; D016016:Proportional Hazards Models; D011446:Prospective Studies; D051437:Renal Insufficiency / Q000097:blood / Q000503:physiopathology / Q000628:therapy; D013223:Statistics as Topic; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology
D015415:Biomarkers; D003404:Creatinine