Reperfusion injury in renal transplantation: comparison of LD, HBD and NHBD renal transplants.
Comparison of reperfusion injury in kidneys transplanted from LD, HBD or NHBD donors is presented in the paper. Central venous blood samples (taken during perioperative period) was assessed for free radicals, total antioxidant activity and various markers of tissue injury. There was demonstrable ischemia reperfusion injury occurring at the time of revascularization, which was particularly notable in kidneys transplanted from NHBD donors.
Gok
M A
MA
Renal/Liver Transplant Unit, The Freeman Hospital, Newcastle Upon Tyne, England, UK. M.A.Gok@ncl.ac.uk
Shenton
B K
BK
Pelsers
M
M
Whitwood
A
A
Mantle
D
D
Cornell
C
C
Peaston
R
R
Rix
D
D
Jaques
B C
BC
Soomro
N A
NA
Manas
D M
DM
Talbot
D
D
D000328:Adult; D015415:Biomarkers / Q000032:analysis; D002102:Cadaver; D006323:Heart Arrest; D006801:Humans; D015994:Incidence; D007668:Kidney / Q000098:blood supply* / Q000378:metabolism; D016030:Kidney Transplantation; D019520:Living Donors; D008875:Middle Aged; D017382:Reactive Oxygen Species / Q000378:metabolism; D015427:Reperfusion Injury / Q000453:epidemiology* / Q000378:metabolism; D014019:Tissue Donors
D015415:Biomarkers; D017382:Reactive Oxygen Species