Any increased risk of autoimmune disease?
Autoimmune diseases such as systemic lupus erythematosus (SLE) are known to have a strong genetic component, therefore the risk of autoimmune disease might be increased in family members of patients with SLE. However, there are currently no data that support a higher incidence of autoimmune disorders in the offspring of SLE patients. Babies with neonatal lupus are not at increased risk to develop SLE in later life, but a continued follow-up is suggested, especially prior to adolescence and if the mother herself has an autoimmune disease.
Department of Pediatrics, Istituti Clinici di Perfezionamento, Milano, Italy. rolando.cimaz@unimi.it
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D001327:Autoimmune Diseases / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease; D006327:Heart Block / Q000209:etiology / Q000235:genetics; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000235:genetics; D008177:Lupus Vulgaris / Q000235:genetics; D011247:Pregnancy; D011248:Pregnancy Complications; D012307:Risk Factors