Highly regioselective nucleophilic carbon-carbon bond formation on furans and thiophenes initiated by pummerer-type reaction.
[reaction: see text] The reactions of (phenylsulfinyl)furans or -thiophenes with carbon nucleophiles in the presence of trifluoroacetic anhydride allowed the nucleophilic installation of carbon functional groups on the furan and thiophene nuclei with complete regioselectivity.
Akai
Shuji
S
Graduate School of Pharmaceutical Sciences, Osaka University, 1-6, Yamada-oka, Suita, Osaka 565-0871, Japan.
Kawashita
Norihito
N
Satoh
Hideharu
H
Wada
Yasufumi
Y
Kakiguchi
Keisuke
K
Kuriwaki
Ikumi
I
Kita
Yasuyuki
Y