Spontaneous renal allograft rupture without acute rejection.
Renal allograft rupture (RAR) is a rare but potentially serious complication in the transplanted recipients. The most common cause is acute rejection. We report four cases (0.5%) of RAR occurred in a series of 778 consecutive kidney transplantations due to severe acute tubular necrosis and renal vein thrombosis with no evidence of acute rejection. Transplant nephrectomy was performed in three patients, whereas graft repair was achieved in one patient. These data suggest that RAR may be associated with renal vein thrombosis or severe acute tubular necrosis in absence of acute rejection. Frequently nephrectomy is necessary, but conservative surgical treatment should be attempted to preserve the allograft in selected cases.
Department of Surgery, Institute of General Surgery and Organ Transplantation, University of Parma, Italy. busi@nemo.unipr.it
Nicola
N
Busi
Enzo
E
Capocasale
Maria Patrizia
MP
Mazzoni
Luisa
L
Benozzi
Raffaele Dalla
RD
Valle
Vincenzo
V
Cambi
Mario
M
Sianesi
D000328:Adult; D005260:Female; D006406:Hematoma / Q000209:etiology; D006801:Humans; D007238:Infarction / Q000209:etiology; D007674:Kidney Diseases / Q000209:etiology* / Q000601:surgery; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation; D007683:Kidney Tubular Necrosis, Acute / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D011183:Postoperative Complications / Q000209:etiology* / Q000601:surgery; D012082:Renal Veins; D012422:Rupture, Spontaneous; D013526:Surgical Mesh; D013536:Suture Techniques; D014180:Transplantation / Q000473:pathology*; D014184:Transplantation, Homologous; D020246:Venous Thrombosis / Q000150:complications*