Metastatic lesions involving the sella: report of three cases and review of the literature.
Metastatic cancer must be considered as a possibility for intrasellar masses. Newer treatment modalities, such as gamma knife radiosurgery needs to be explored for these lesions. Three cases of intrasellar metastatic lesions were retrospectively reviewed. Presenting complaints, radiographic studies, operative procedure, and histopathological confirmation were recorded for each patient. All had an unknown primary malignancy prior to the presentation with the intrasellar lesion detected by magnetic resonance imaging (MRI). Presenting symptoms were diplopia with extraocular movement deficits in all patients. Transsphenoidal resection or biopsy was performed. Histopathological analysis revealed small cell carcinoma in two patients and plasmacytoma in one. All patients received postoperative radiation and/or chemotherapy. Survival following initial presentation was 2 months and 6 months for two of the patients; the third patient is alive at 2-month follow-up.
Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA.
Christina
C
Weilbaecher
Ravish V
RV
Patwardhan
Marjorie
M
Fowler
Brian K
BK
Willis
Anil
A
Nanda
D000368:Aged; D018288:Carcinoma, Small Cell / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000473:pathology; D009460:Neurologic Examination; D019635:Neurosurgical Procedures; D010911:Pituitary Neoplasms / Q000473:pathology / Q000556:secondary*; D010954:Plasmacytoma / Q000473:pathology; D012658:Sella Turcica