[T-lymphocyte subpopulations and tumor necrosis factor-alpha in patients with acute Flexner's dysentery].
In 41 patients aged 24-63 years with acute Flexner's dysentery T-lymphocyte subpopulations CD-3, CD-4, CD-8, IRI and the content of tumor necrosis factor alpha (TNF-alpha) in the blood serum were detected. The suppression of T-cell mediated immunity on account of the presence of CD-4 with decreased immunoregulatory index and an increased content of TNF-alpha were established. Changes in T-cell mediated immunity and TNF-alpha depended on the period and the severity of the diseases.
Nagoev
B S
BS
Marzhokhova
M Iu
MIu
D000208:Acute Disease; D000328:Adult; D017252:CD3 Complex / Q000032:analysis; D015704:CD4 Antigens / Q000032:analysis; D016827:CD8 Antigens / Q000032:analysis; D004405:Dysentery, Bacillary / Q000097:blood / Q000276:immunology*; D006801:Humans; D018655:Lymphocyte Count; D008875:Middle Aged; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis
D017252:CD3 Complex; D015704:CD4 Antigens; D016827:CD8 Antigens; D014409:Tumor Necrosis Factor-alpha