[The head MRI by fluid attenuated inversion recovery (FLAIR) was useful for diagnosis in the patient with post influenza vaccinal acute disseminated encephalomyelitis (ADEM)].
A 6-year-old, previously healthy boy developed ataxia and muscle weakness, 16 days after influenza vaccination. The CSF showed an elevated level of myelin basic protein, pleocytosis and negative influenza virus isolation. The head MRI revealed an extensive high intensity area in the deep white matter, which was more clearly defined on FLAIR images. The diagnosis of post influenza vaccinal ADEM was made, and he was successfully treated by steroid pulse therapy with a monophasic course and favorable outcome.
Iyoda
Kuniaki
K
Department of Pediatrics, Hiroshima City Hospital, Hiroshima. kuiyoda@av6.mopera.ne.jp
Mitsuda
Naomi
N
Ogawa
Kazunori
K
Okazaki
Tomio
T
D002648:Child; D004673:Encephalomyelitis, Acute Disseminated / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007252:Influenza Vaccines / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D011239:Prednisolone / Q000008:administration & dosage; D020551:Pulse Therapy, Drug; D016896:Treatment Outcome
D007252:Influenza Vaccines; D011239:Prednisolone; D008775:Methylprednisolone