Multiple-antibiotic resistance of Enterococcus spp. isolated from commercial poultry production environments.
The potential impact of food animals in the production environment on the bacterial population as a result of antimicrobial drug use for growth enhancement continues to be a cause for concern. Enterococci from 82 farms within a poultry production region on the eastern seaboard were isolated to establish a baseline of susceptibility profiles for a number of antimicrobials used in production as well as clinical environments. Of the 541 isolates recovered, Enterococcus faecalis (53%) and E. faecium (31%) were the predominant species, while multiresistant antimicrobial phenotypes were observed among all species. The prevalence of resistance among isolates of E. faecalis was comparatively higher among lincosamide, macrolide, and tetracycline antimicrobials, while isolates of E. faecium were observed to be more frequently resistant to fluoroquinolones and penicillins. Notably, 63% of the E. faecium isolates were resistant to the streptogramin quinupristin-dalfopristin, while high-level gentamicin resistance was observed only among the E. faecalis population, of which 7% of the isolates were resistant. The primary observations are that enterococci can be frequently isolated from the poultry production environment and can be multiresistant to antimicrobials used in human medicine. The high frequency with which resistant enterococci are isolated from this environment suggests that these organisms might be useful as sentinels to monitor the development of resistance resulting from the usage of antimicrobial agents in animal production.
Hayes
Joshua R
JR
Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA.
English
Linda L
LL
Carr
Lewis E
LE
Wagner
David D
DD
Joseph
Sam W
SW
D000822:Animal Husbandry; D000818:Animals; D002645:Chickens / Q000382:microbiology*; D024901:Drug Resistance, Multiple, Bacterial; D016983:Enterococcus / Q000187:drug effects* / Q000302:isolation & purification* / Q000472:pathogenicity; D013293:Enterococcus faecalis / Q000187:drug effects / Q000302:isolation & purification / Q000472:pathogenicity; D016984:Enterococcus faecium / Q000187:drug effects / Q000302:isolation & purification / Q000472:pathogenicity; D005516:Food Microbiology; D006801:Humans; D008826:Microbial Sensitivity Tests; D010641:Phenotype; D013045:Species Specificity