Effect of Saiko-ka-ryukotsu-borei-to on amylase activity in mice.
The effects of Saiko-ka-ryukotsu-borei-to (SRBT), a Chinese medicinal prescription, on mouse serum amylase activity were investigated in vivo. SRBT was found to not only dose- and/or time-dependently augment amylase activity, but also to increase alpha-amylase protein content and soluble starch metabolic activity. These results provide a rational basis for the clinical use of SRBT that may accompany disease therapy.
Department of Pharmacognosy, Tohoku Pharmaceutical University, Aoba-ku, Sendai, Japan. kenrs@tohoku-pharm.ac.jp
Kenroh
K
Sasaki
So-ichi
S
Ito
Yusuke
Y
Nakamura
Fumihiko
F
Yoshizaki
D000818:Animals; D001786:Blood Glucose / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000494:pharmacology*; D004591:Electrophoresis, Polyacrylamide Gel; D008297:Male; D051379:Mice; D012995:Solubility; D013213:Starch / Q000737:chemistry; D000516:alpha-Amylases / Q000097:blood*
D001786:Blood Glucose; D004365:Drugs, Chinese Herbal; C095444:saiko-ka-ryukotsu-borei-to; D013213:Starch; D000516:alpha-Amylases