Three cases of Q fever osteomyelitis in children and a review of the literature.
Q fever is a common zoonosis worldwide. Awareness of the disease and newer diagnostic modalities have resulted in increasing recognition of unusual manifestations. We report 3 cases of Q fever osteomyelitis in children and review the literature on 11 other reported cases. The cases demonstrate that Coxiella burnetii can cause granulomatous osteomyelitis that presents without systemic symptoms and frequently results in a chronic, relapsing, multifocal clinical course. Optimal selection and duration of antimicrobial therapy and methods of monitoring therapy are currently uncertain.
Department of Paediatrics, Mater Children's Hospital, South Brisbane, Australia. clare_nourse@mater.org.au
Clare
C
Nourse
Anthony
A
Allworth
Andrew
A
Jones
Robert
R
Horvath
Joe
J
McCormack
Jeremy
J
Bartlett
David
D
Hayes
Jennifer M
JM
Robson
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D011778:Q Fever / Q000175:diagnosis* / Q000473:pathology
D000900:Anti-Bacterial Agents