Global nucleosome distribution and the regulation of transcription in yeast.
Recent studies show that active regulatory regions of the yeast genome have a lower density of nucleosomes than other regions, and that there is an inverse correlation between nucleosome density and the transcription rate of a gene. This may be the result of transcription factors displacing nucleosomes.
Stowers Institute for Medical Research, 1,000 East 50th Street, Kansas City, MO 64110, USA.
Sevinc
S
Ercan
Michael J
MJ
Carrozza
Jerry L
JL
Workman
D015966:Gene Expression Regulation, Fungal / Q000235:genetics*; D016681:Genome, Fungal; D009707:Nucleosomes / Q000235:genetics* / Q000378:metabolism*; D014158:Transcription, Genetic / Q000235:genetics*; D015003:Yeasts / Q000235:genetics*
D009707:Nucleosomes