Sugar-sensitive thin films composed of concanavalin A and glycogen.
Sugar-sensitive thin films were prepared by a layer-by-layer deposition of concanavalin A (Con A) and glycogen on the surface of a quartz slide and their sugar-induced decomposition was studied. The Con A/glycogen multilayer films can be decomposed by exposing them to sugar solutions (D-glucose, D-mannose, methyl-alpha-D-glucose and methyl-alpha-D-mannose), as a result of displacement of sugar residues of glycogen from the binding sites of Con A by the free sugar added in the solution. The rate of decomposition significantly depended on the type of sugar and its concentration.
Graduate School of Pharmaceutical Sciences, Tohoku University, Aramaki, Aoba-ku, Sendai 980-8578, Japan.
Katsuhiko
K
Sato
Yoko
Y
Imoto
Jun
J
Sugama
Shunsuke
S
Seki
Hiroyuki
H
Inoue
Tsuyoshi
T
Odagiri
Jun-ichi
J
Anzai