Matrix metalloproteinase-1 promoter polymorphisms and changes in left ventricular volume following acute myocardial infarction.
The relation between matrix metalloproteinase-1 promoter genotype and remodeling was studied in 42 patients after their first acute myocardial infarctions. Patients possessing 2 GG alleles were at increased risk for remodeling compared with homozygotes for the G allele and heterozygotes possessing 1 G and 1 GG allele.
Department of Cardiology, Western Infirmary/University of Glasgow, Glasgow, Scotland, United Kingdom.
Thomas N
TN
Martin
Dawn E
DE
Penney
Jamie A
JA
Smith
Bjoern A
BA
Groenning
Henry J
HJ
Dargie
Graham S
GS
Hillis
D000368:Aged; D002306:Cardiac Volume; D005260:Female; D006352:Heart Ventricles; D006801:Humans; D008297:Male; D020781:Matrix Metalloproteinase 1 / Q000235:genetics*; D008875:Middle Aged; D009203:Myocardial Infarction / Q000235:genetics* / Q000503:physiopathology*; D011110:Polymorphism, Genetic
D020781:Matrix Metalloproteinase 1