[Prophylaxis of wound infection with immobilized antibacterial drugs].
New drug ambipor that is an immobilized antibacterial agent with local prolonged therapeutic activity was developed for prophylaxis of wound suppuration. In ambipor A drugs gentamicin, dioxidin, kephzol and riphampicin are immobilazed, in iodopor - iodine. Experimental studies on 455 white rats showed that ambipor prevents suppuration, abscess formation around ligatures, improve regeneration and fibrillogenesis. In clinical practice ambipor A and iodopor were used in 562 patients. Rate of suppuration decreased from 11.7 to 2.3% compared with control group of patients.
A V
AV
Bolenko
D D
DD
Men'shikov
G P
GP
Titov
S V
SV
Kuprikov
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D014946:Wound Infection / Q000382:microbiology / Q000473:pathology / Q000517:prevention & control*
D000900:Anti-Bacterial Agents; D005839:Gentamicins