[Total intravenous anesthesia with ketamine and the condition of the higher psychic function in the early and remote postoperative periods].
Influence of total intravenous anesthesia with ketamine on the higher psychic function was studied, immediately after surgery and in the remote postoperative period, in 143 patients with different typological properties of the nervous system after a scheduled surgery--supravaginal uterectomy in fibromyoma of the uterine body. The authors defined 6 groups of patients with different typological properties of the nervous system. Persistent impairment of the higher nervous functions were established, immediately after surgery and in the remote postoperative period, in patients with a weak nervous system, biased nervous balance towards excitation, and with lability of nervous processes. Total intravenous anesthesia with ketamine, when used in patients with the robust nervous system, biased nervous balance towards excitation, and with lability of nervous processes, caused changes in the higher nervous functions and an intensified level of nervous-and-psychic loads, which were unstable and were arrested by the 30th postoperative day. The use of such anesthetic scheme was found to be inadvisable in the above groups of patients. The described impairments were not registered when total intravenous anesthesia was used in patients with a balanced nervous system irrespective of its type, a biased nervous balance towards inhibition and with inertness of nervous processes. The above anesthetic management is acceptable for such patients.
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Davydov
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Neĭmark
D000328:Adult; D000762:Anesthesia Recovery Period; D000771:Anesthesia, Intravenous; D000778:Anesthetics, Dissociative / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007649:Ketamine / Q000009:adverse effects*; D008606:Mental Processes / Q000187:drug effects*; D008875:Middle Aged; D009420:Nervous System / Q000187:drug effects*; D014599:Uterus / Q000601:surgery
D000778:Anesthetics, Dissociative; D007649:Ketamine