Prenatal ultrasound detection of bilateral focal polymicrogyria.
OBJECTIVE
Prenatal diagnosis by ultrasound of fetal polymicrogyria has been reported only once.


METHODS
We describe an additional case of polymicrogyria in a fetus from a monozygotic twin pair, probably the consequence of twin-to-twin transfusion syndrome.


RESULTS
On ultrasound, there were bilateral cortical hyperechogenic spots, and prenatal magnetic resonance imaging demonstrated the typical features of bilateral focal polymicrogyria.


CONCLUSIONS
Polymicrogyria can be considered in the differential diagnosis of hyperechogenic brain lesions on fetal ultrasound. We also confirm the risk of brain damage in monochorionic twins pregnancies and the likely hypoxic-ischemic etiology of polymicrogyria.
Delle Urban
Linei Augusta Brolini
LA
Department of Radiology and Neuroradiology, Ospedale Buzzi-ICP, Milano, Italy. lineiurban@hotmail.com
Righini
Andrea
A
Rustico
Mariangela
M
Triulzi
Fabio
F
Nicolini
Umberto
U
D000328:Adult; D005260:Female; D005330:Fetofetal Transfusion / Q000150:complications*; D005625:Frontal Lobe / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000196:embryology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009421:Nervous System Malformations / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000196:embryology / Q000209:etiology; D010296:Parietal Lobe / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000196:embryology; D011247:Pregnancy; D014430:Twins, Monozygotic; D016216:Ultrasonography, Prenatal