Photochemical production of nitric oxide via two-photon excitation with NIR light.
Herein we demonstrate the successful photochemical generation of nitric oxide via two-photon excitation (TPE) from the supramolecular complex PPIX-RSE ({mu-S,mu-S'-protoporphyrin-IX-bis(2-thioethyl)diester]tetranitrosyl-diiron). The TPE fluorescence spectra indicate efficient energy transfer from the PPIX antennae to the iron sulfur nitrosyl cluster. Further evidence of NO release is demonstrated using a nitric oxide specific electrode and ESI+ MS.
Wecksler
Stephen
S
Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, California 93106-9510, USA.
Mikhailovsky
Alexander
A
Ford
Peter C
PC
D004566:Electrodes; D007259:Infrared Rays; D010088:Oxidoreductases / Q000138:chemical synthesis* / Q000737:chemistry; D010777:Photochemistry; D017785:Photons; D017319:Photosensitizing Agents / Q000737:chemistry; D011524:Protoporphyrins / Q000737:chemistry; D013050:Spectrometry, Fluorescence
D017319:Photosensitizing Agents; D011524:Protoporphyrins; C028025:protoporphyrin IX; D010088:Oxidoreductases; C034747:nitric-oxide reductase