Treatment of recurrent bacterial vaginosis with tinidazole.
BACKGROUND
Recurrent bacterial vaginosis is a difficult clinical condition. In women with recurrent bacterial vaginosis, relapses are common, even after prolonged courses of maintenance therapy. Because of its spectrum of activity, tinidazole was used in a patient with recurrent bacterial vaginosis.


METHODS
A 23-year-old woman taking oral contraceptives had a single sexual partner. She was treated for recurrent bacterial vaginosis with multiple courses of metronidazole gel 0.75%, including regimens of maintenance therapy. The patient experienced repeated recurrences shortly after stopping treatment. A single course of oral tinidazole resulted in a prolonged period where she was free of bacterial vaginosis.


CONCLUSIONS
Treatment options for recurrent bacterial vaginosis are currently limited. Tinidazole may be a useful option in women with recurrent bacterial vaginosis.
Baylson
F Ariella
FA
Department of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Nyirjesy
Paul
P
Weitz
M Velma
MV
D000328:Adult; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D000994:Antitrichomonal Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use*; D012008:Recurrence; D014011:Tinidazole / Q000627:therapeutic use*; D016585:Vaginosis, Bacterial / Q000188:drug therapy*
D000981:Antiprotozoal Agents; D000994:Antitrichomonal Agents; D014011:Tinidazole; D008795:Metronidazole