[A complete response using TS-1 in a patient with paramesenteric lymph node recurrence of gastric cancer].
A 86-year-old male patient underwent distal gastrectomy, D2 lymph node dissection for type 2 gastric cancer. Five months after the surgery, abdominal computed tomography (CT) revealed paramesenteric vein lymph node recurrence (# 14v), 12 mm in size. TS-1 (80 mg/day) was administered for 28 days, followed by 14 days rest, as one course. A complete response was obtained after the second course. The patient has been in good health without a recurrence for 36 weeks after 5 courses. As for adverse events, leukopenia (grade 2) was observed temporarily but required no treatment.
Yasutomo
Noriyuki
N
Dept. of Surgery, Ishikari Hospital.
Kawabata
Mikio
M
D000368:Aged; D000369:Aged, 80 and over; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008638:Mesenteric Arteries; D010094:Oxonic Acid / Q000627:therapeutic use*; D011184:Postoperative Period; D011725:Pyridines / Q000627:therapeutic use*; D012008:Recurrence; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000601:surgery*; D005641:Tegafur / Q000627:therapeutic use*
D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid