title: Topically applied vitamins and their cutaneous effects.
abstract: The number of cosmetic products which include vitamins as a constituent has increased three-fold since 1991. Vitamins are commonly used as ingredients of products designed to improve the appearance and health of the skin; for this reason the cutaneous benefits of such products are actively researched by dermatologists and chemists. The present study does a review of the action of topically applied vitamins for local use which improves the function of the skin. We specifically consider the biologic activity of topically applied vitamins, their stability and usefulness. Ways of stabilizing different kinds of vitamins, as well as their stability to oxygen, light, temperature, acids, and bases, are shown. The conclusion suggested by the review is that the efficiency of topically applied vitamins is dependent not only on their good stabilization and concentration but also on the clinical individual tests that can determine the best product for each particular patient.
authors.affiliation: Department of Aesthetics, Technological Institution, Thessalonica, Greece.
authors.forename: George T
authors.initials: GT
authors.lastname: Grammaticopoulos
authors.forename: Demetrios G
authors.initials: DG
authors.lastname: Furtunopoulos
authors.forename: Lilia G
authors.initials: LG
authors.lastname: Zisova
mesh_terms: D000287:Administration, Topical; D003358:Cosmetics / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D012867:Skin / Q000187:drug effects*; D012869:Skin Absorption; D014815:Vitamins / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D003358:Cosmetics; D014815:Vitamins