title: DOTS centre at a tertiary care teaching hospital: lessons learned and future directions.
abstract: BACKGROUND
  In 1993, Government of India started the Revised National Tuberculosis Control Programme (RNTCP). A model Directly Observed Therapy, Short-Course (DOTS) centre was established at the All India Institute of Medical Sciences (AIIMS) to (i) identify the challenges and opportunities in establishing DOTS centres at tertiary care facilities, (ii) to teach the strategies of RNTCP to medical and paramedical staff, and (iii) to undertake relevant operational research connected with tuberculosis (TB) treatment and control. In this communication, we describe the experience of establishing a DOTS centre at India's premier medical institute and discuss the lessons learned.
  
  
  METHODS
  Since September 2001 through November 2002 AIIMS employees and their dependants diagnosed with tuberculosis were enrolled for treatment at AIIMS DOTS centre. One hundred sixty-eight patients were diagnosed as suffering from tuberculosis. Of these 49 patients were referred out and remaining 119 patients were treated at AIIMS DOTS centre.
  
  
  RESULTS
  Treatment success was achieved in 80% (20/25) of new smear positive cases and the DOTS centre achieved other targets set up by the RNTCP. As the results of the pilot study at AIIMS DOTS centre were favourable, the facilities of AIIMS DOTS centre were extended to the general public from September 2002 onwards.
  
  
  CONCLUSIONS
  Despite tremendous patient load at tertiary care facilities, it is possible to achieve targets established by the RNTCP. However, additional research needs to be conducted especially relating to drug resistance and surrogate markers of failure under RNTCP.
authors.affiliation: Department of Medicine, All India Institute of Medical Sciences, New Delhi, India. sksharma@aiims.ac.in
authors.forename: S K
authors.initials: SK
authors.lastname: Sharma
authors.forename: S
authors.initials: S
authors.lastname: Lawaniya
authors.forename: H
authors.initials: H
authors.lastname: Lal
authors.forename: U B
authors.initials: UB
authors.lastname: Singh
authors.forename: P K
authors.initials: PK
authors.lastname: Sinha
mesh_terms: D000328:Adult; D003140:Communicable Disease Control / Q000458:organization & administration; D023801:Directly Observed Therapy; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D007194:India; D008297:Male; D014376:Tuberculosis / Q000517:prevention & control*; D014397:Tuberculosis, Pulmonary / Q000517:prevention & control