title: What predicts suicide attempts in women with eating disorders?
abstract: BACKGROUND
  Suicide is a common cause of death in anorexia nervosa and suicide attempts occur often in both anorexia nervosa and bulimia nervosa. No studies have examined predictors of suicide attempts in a longitudinal study of eating disorders with frequent follow-up intervals. The objective of this study was to determine predictors of serious suicide attempts in women with eating disorders.
  
  
  METHODS
  In a prospective longitudinal study, women diagnosed with either DSM-IV anorexia nervosa (n = 136) or bulimia nervosa (n = 110) were interviewed and assessed for suicide attempts and suicidal intent every 6-12 months over 8.6 years.
  
  
  RESULTS
  Fifteen percent of subjects reported at least one prospective suicide attempt over the course of the study. Significantly more anorexic (22.1%) than bulimic subjects (10.9%) made a suicide attempt. Multivariate analyses indicated that the unique predictors of suicide attempts for anorexia nervosa included the severity of both depressive symptoms and drug use over the course of the study. For bulimia nervosa, a history of drug use disorder at intake and the use of laxatives during the study significantly predicted suicide attempts.
  
  
  CONCLUSIONS
  Women with anorexia nervosa or bulimia nervosa are at considerable risk to attempt suicide. Clinicians should be aware of this risk, particularly in anorexic patients with substantial co-morbidity.
authors.affiliation: Harvard Eating Disorders Center, Massachusetts General Hospital, Boston, MA 02114, USA. d.franko@neu.edu
authors.forename: D L
authors.initials: DL
authors.lastname: Franko
authors.forename: P K
authors.initials: PK
authors.lastname: Keel
authors.forename: D J
authors.initials: DJ
authors.lastname: Dorer
authors.forename: M A
authors.initials: MA
authors.lastname: Blais
authors.forename: S S
authors.initials: SS
authors.lastname: Delinsky
authors.forename: K T
authors.initials: KT
authors.lastname: Eddy
authors.forename: V
authors.initials: V
authors.lastname: Charat
authors.forename: R
authors.initials: R
authors.lastname: Renn
authors.forename: D B
authors.initials: DB
authors.lastname: Herzog
mesh_terms: D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000175:diagnosis / Q000453:epidemiology; D002032:Bulimia / Q000175:diagnosis / Q000453:epidemiology; D039721:Diagnostic and Statistical Manual of Mental Disorders; D001068:Feeding and Eating Disorders / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D013406:Suicide, Attempted / Q000706:statistics & numerical data*