Tissue homeostasis of the myocardium in newborn albino rats exposed to intrauterine hypoxia.
Somatometric indexes were modified in the offspring of rats exposed to hypobaric hypoxia. DNA synthesis and tissue mitotic index increased in 5-day-old male rats, but underwent less pronounced changes in females. Our results indicate that hypoxia modulates morphogenesis of the myocardium. We revealed sex differences in the reaction of newborn albino rats to intrauterine hypoxia.
Kryzhanovskaya
S Yu
SY
Central Research Laboratory, Far-Eastern State Medical University, Khabarovsk.
Sazonova
E N
EN
Timoshin
S S
SS
D000818:Animals; D000831:Animals, Newborn; D001274:Atmospheric Pressure; D001345:Autoradiography; D002466:Cell Nucleolus / Q000378:metabolism; D004247:DNA / Q000096:biosynthesis; D005260:Female; D005311:Fetal Hypoxia; D006706:Homeostasis; D000860:Hypoxia / Q000378:metabolism*; D008297:Male; D008940:Mitotic Index; D009206:Myocardium / Q000166:cytology / Q000378:metabolism*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D012737:Sex Factors
D004247:DNA