title: Synchronous solitary metastasis of transitional cell carcinoma of the bladder to the testis.
abstract: Primary tumors known to metastasize to the testis, in order of decreasing frequency, are prostate, lung, gastrointestinal tract, melanoma, and kidney tumors. Metastasis from bladder cancer to the testis is extremely rare, occurs with advanced and metastatic disease, and is usually a finding at autopsy. We report a rare, and probably the first, case of solitary and synchronous metastatic transitional cell carcinoma of the bladder to the testis, discovered on the preoperative workup. An incidentally discovered testicular mass in a man with high-grade, invasive bladder cancer should be considered a metastatic lesion until proven otherwise.
authors.affiliation: Department of Urology, Stanford University School of Medicine and Palo Alto Veterans Affairs Medical Center, Stanford, California, USA.
authors.forename: Kelly
authors.initials: K
authors.lastname: Morgan
authors.forename: Sandy
authors.initials: S
authors.lastname: Srinivas
authors.forename: Fuads
authors.initials: F
authors.lastname: Freiha
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002295:Carcinoma, Transitional Cell / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D015653:Cystectomy; D003556:Cystitis / Q000150:complications / Q000175:diagnosis; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D006417:Hematuria / Q000209:etiology; D006801:Humans; D033162:Incidental Findings; D008297:Male; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000601:surgery; D016609:Neoplasms, Second Primary; D009919:Orchiectomy; D049268:Positron-Emission Tomography; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary; D011832:Radiation Injuries / Q000150:complications / Q000175:diagnosis; D013736:Testicular Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D020728:Transurethral Resection of Prostate; D014463:Ultrasonography; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D014547:Urinary Diversion; D000093542:Gemcitabine
chemical_list: D003841:Deoxycytidine; D002945:Cisplatin; D000093542:Gemcitabine