Genes encoding vitamin-K epoxide reductase are present in Drosophila and trypanosomatid protists.
Vitamin-K epoxide reductase is encoded by the VKORC1 gene in mammals and other vertebrates, which also have a paralog, VKORC1L1. Single homologs are present in basal deuterostome and insect genomes, including Drosophila, and three trypanosomatid protists. VKOR is therefore an ancient gene/protein that can be studied in the Drosophila model system.
Robertson
Hugh M
HM
Department of Entomology, University of Illinois, Urbana, Illinois 61801, USA. hughrobe@uiuc.edu
D000818:Animals; D004331:Drosophila melanogaster / Q000201:enzymology / Q000235:genetics*; D006899:Mixed Function Oxygenases / Q000235:genetics*; D010802:Phylogeny; D014345:Trypanosoma / Q000201:enzymology / Q000235:genetics*; D064417:Vitamin K Epoxide Reductases
D006899:Mixed Function Oxygenases; D064417:Vitamin K Epoxide Reductases