title: Routine lumbar puncture in children with febrile seizures in Ghana: should it continue?
abstract: OBJECTIVE
  Performing routine lumbar punctures in children with febrile seizures has been controversial. This study aimed to determine the positive yield of lumbar punctures in a setting where routine lumbar puncture is routinely carried out and to determine if any other parameter could help differentiate bacterial meningitis from the various other diagnoses of children who presented with a febrile seizure.
  
  
  METHODS
  A prospective study was carried out among children aged three months to 15 years of age, hospitalized at the Komfo Anokye Teaching Hospital in Kumasi, Ghana, between July and August 2000.
  
  
  RESULTS
  There was a 10.2% (n = 19) positive yield for bacterial meningitis with a case fatality rate of 36.8% (n = 7). Cerebral malaria, which is not easily distinguishable from bacterial meningitis, accounted for 16.1% (n = 30) of the children. Twenty percent of bacterial meningitis patients had a positive blood smear for malaria. The indication for doing a lumbar puncture was similar in both cerebral malaria and bacterial meningitis patients. Signs of meningism were not the primary reason for carrying out a lumbar puncture, even in the group of children who had bacterial meningitis.
  
  
  CONCLUSIONS
  Performing routine lumbar punctures may still have a role to play in the management of children with febrile seizures.
authors.affiliation: Department of Child Health, Komfo Anokye Teaching Hospital, P.O. Box 1934, Kumasi, Ghana. malab@ghana.com
authors.forename: Alex
authors.initials: A
authors.lastname: Owusu-Ofori
authors.forename: Tsiri
authors.initials: T
authors.lastname: Agbenyega
authors.forename: Daniel
authors.initials: D
authors.lastname: Ansong
authors.forename: W Michael
authors.initials: WM
authors.lastname: Scheld
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D005869:Ghana; D006801:Humans; D007223:Infant; D008288:Malaria / Q000150:complications / Q000175:diagnosis; D016779:Malaria, Cerebral / Q000150:complications / Q000175:diagnosis*; D008297:Male; D016920:Meningitis, Bacterial / Q000150:complications / Q000175:diagnosis*; D011446:Prospective Studies; D003294:Seizures, Febrile / Q000209:etiology*; D013129:Spinal Puncture