[Secondary surfactant deficiencies in extremely low birth weight premature infants].
Primary deficiency of surfactant is responsible for the respiratory distress syndrome and concerns premature neonates born before 33 weeks of gestation. However, newborns may develop respiratory disorders related to a secondary deficiency or dysfunction of surfactant. We report the course of three extremely low birth weight premature infants who experienced clinical respiratory decompensation at two weeks and showed a marked improvement after exogenous natural surfactant administration.
Rivera
S
S
Service de pédiatrie II, médecine néonatale et réanimation pédiatrique, hôpital de Hautepierre, hôpitaux universitaires de Strasbourg, avenue Molière, 67098 Strasbourg cedex, France.
Gaugler
C
C
Langlet
C
C
Villega
F
F
Astruc
D
D
Escande
B
B
Kuhn
P
P
Messer
J
J
D006801:Humans; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D011379:Prognosis; D011663:Pulmonary Surfactants / Q000627:therapeutic use*; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology* / Q000473:pathology; D016896:Treatment Outcome
D011663:Pulmonary Surfactants