[Pulmonary hypertension--some problems resolved. More remain to be solved].
Pulmonary hypertension especially arterial and idiopathic is still a poorly understood disease often affecting young adults and leading to right ventricular overload, failure and death due to low cardiac output. Justification for new, aggressive, costly but effective methods of pharmacological and interventional treatment of pulmonary hypertension require precise, repeatedly performed prognostic assessment. This is currently provided not only by repeated right heart catheterization but mostly by exercise testing as well as non-invasive techniques such as echo-Doppler and biochemical myocyte markers including B-type natriuretic peptide and cardiac troponin. Such methods should allow better timing of atrial septostomy and listing for lung transplantation.
Torbicki
Adam
A
Klinika Chorób Wewnetrznych Instytutu Gruźlicy i Chorób Płuc w Warszawie.
D015415:Biomarkers / Q000378:metabolism; D006328:Cardiac Catheterization; D015150:Echocardiography, Doppler; D005080:Exercise Test; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D032383:Myocytes, Cardiac / Q000378:metabolism; D020097:Natriuretic Peptide, Brain / Q000378:metabolism; D011379:Prognosis; D014336:Troponin / Q000378:metabolism; D018497:Ventricular Dysfunction, Right / Q000209:etiology*
D015415:Biomarkers; D014336:Troponin; D020097:Natriuretic Peptide, Brain