[Pathological studies of vocal polyps and vocal nodes].
OBJECTIVE
In order to investigate the pathological differences and similarities of vocal nodes and vocal polyps.


METHODS
144 samples of vocal nodes and vocal polyps were examined by an experienced pathologist.


RESULTS
There were no significant statistical difference in short-term vocal nodes and vocal polyps. In long-term vocal nodes and vocal polyps, vocal nodes had thickened basal membrane, and abnormal keratinization of epithelium, vocal polyps had thin or discrete thickening of basement membrane, more pronounced edema, dilated vessels or growth of new blood vessels.


CONCLUSIONS
It proved that vocal nodes and polyps are the result of "microtraumas" occurring at various phases of wound repair, thus accounting for the homogeneity and heterogeneity of histological and clinical manifestations.
Ding
Guoyu
G
Department of Otolaryngology, People's Hospital of Peking University, Beijing 100044.
Liao
Xiaoyun
X
Yu
Lisheng
L
D000328:Adult; D005260:Female; D006801:Humans; D007818:Laryngeal Diseases / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011127:Polyps / Q000473:pathology*; D014827:Vocal Cords / Q000473:pathology*