title: [Detection of free testosterone in the serum and semen of idiopathic oligospermia patients and its significance].
abstract: OBJECTIVE
  To detect free testosterone (FT) in the serum and semen of patients with idiopathic oligospermia, and further analyze the relationship between FT and idiopathic oligospermia.
  
  
  METHODS
  Blood samples were collected from the males of a normal control group (n = 44) and an idiopathic oligospermia group (n = 44) at 8:00-10:00 a.m.. Semen samples were collected from the males of a normal control group (n = 30) and an idiopathic oligospermia group (n = 37) at the same time. Sperm density was detected by routine semen analysis, and FT in the serum and semen was detected by RIA.
  
  
  RESULTS
  There was no significant difference in the serum concentrations of FT between the groups of normal control [(97.50 +/- 46.96) pmol/L] and idiopathic oligospermia [(94.88 +/- 42.04) pmol/L], P > 0.5. But the difference was significant in the semen concentrations of FT between the groups of normal control [(2.01 +/- 0.32) pmol/L] and idiopathic oligospermia [(0.52 +/- 0.44) pmol/L], P < 0.01.
  
  
  CONCLUSIONS
  Measurement of semen FT concentration could early reflect the function of the testis, which contributes to the early diagnosis and treatment of idiopathic oligospermia.
authors.affiliation: Laboratory of Radioimmunoassay, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.
authors.forename: Guohong
authors.initials: G
authors.lastname: Wang
authors.forename: Ruiji
authors.initials: R
authors.lastname: Xu
authors.forename: Zhongshu
authors.initials: Z
authors.lastname: Zhang
authors.forename: Xiaojie
authors.initials: X
authors.lastname: Wang
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009845:Oligospermia / Q000097:blood / Q000378:metabolism*; D012661:Semen / Q000737:chemistry*; D013739:Testosterone / Q000097:blood / Q000378:metabolism*
chemical_list: D013739:Testosterone