title: Low-grade endometrial stromal sarcoma presenting as vaginal nodule.
abstract: Endometrial stromal sarcoma is a rare neoplasm of the uterus. Extrauterine locations of this neoplasm, excluding metastases or local extension, are even more unusual and are usually associated with the presence of endometriosis. The authors report a case of endometrial stromal sarcoma presenting as a vaginal wall nodule, without any sign of primary uterine tumor after extensive evaluation or presence of endometriosis. The morphology, immunohistochemical profile, differential diagnoses, and pathogenesis are discussed, as well as a review of the literature on this issue.
authors.affiliation: Department of Pathology, State University of São Paulo, Botucatu Campus, State of, São Paulo, Brazil.
authors.forename: Marcus V N
authors.initials: MV
authors.lastname: Corpa
authors.forename: Eduardo P
authors.initials: EP
authors.lastname: Serafini
authors.forename: Carlos E
authors.initials: CE
authors.lastname: Bacchi
mesh_terms: D000328:Adult; D015703:Antigens, CD / Q000378:metabolism; D014408:Biomarkers, Tumor / Q000378:metabolism; D003937:Diagnosis, Differential; D018572:Disease-Free Survival; D016889:Endometrial Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D011960:Receptors, Estrogen / Q000378:metabolism; D011980:Receptors, Progesterone / Q000378:metabolism; D018203:Sarcoma, Endometrial Stromal / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D039961:Semaphorins / Q000378:metabolism; D014625:Vaginal Neoplasms / Q000473:pathology*
chemical_list: D015703:Antigens, CD; D014408:Biomarkers, Tumor; C093224:CD100 antigen; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D039961:Semaphorins