title: Effect of intra-abdominal pressure level on gastric intramucosal pH during pneumoperitoneum.
abstract: The present study was designed to examine the effect of intra-abdominal pressure level on gastric intramucosal pH using gastric tonometry during pneumoperitoneum. One hundred patients were prospectively randomized into 5 equal groups (N = 20 each). Intra-abdominal pressure levels were 8, 10, 12, 14, and 16 mm Hg in groups I, II, III, IV, and V, respectively. Intramucosal pH measurement was done 2 times: 30 minutes following insufflation and 1 hour after the ending of the surgery. In the first and second measurements, intramucosal pH values were found as 7.39 +/- 0.02 and 7.36 +/- 0.03 in group I; 7.41 +/- 0.03 and 7.38 +/- 0.03 in group II; 7.37 +/- 0.03 and 7.37 +/- 0.03 in group III; 7.36 +/- 0.03 and 7.37 +/- 0.03 in group IV; and 7.39 +/- 0.03, 7.36 +/- 0.03 in group V, respectively. Statistical significance was not found in the comparison of these values within the groups and between the groups (P > 0.005, for each). In conclusion, intra-abdominal pressure between 8 and 16 mm Hg did not cause significant difference in gastric intramucosal pH.
authors.affiliation: Department of General Surgery, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey. varolcelik@yahoo.com
authors.forename: Varol
authors.initials: V
authors.lastname: Celik
authors.forename: Ziya
authors.initials: Z
authors.lastname: Salihoglu
authors.forename: Sener
authors.initials: S
authors.lastname: Demiroluk
authors.forename: Ethem
authors.initials: E
authors.lastname: Unal
authors.forename: Nihat
authors.initials: N
authors.lastname: Yavuz
authors.forename: Saffet
authors.initials: S
authors.lastname: Karaca
authors.forename: Sinan
authors.initials: S
authors.lastname: Carkman
authors.forename: Oznur
authors.initials: O
authors.lastname: Demiroluk
mesh_terms: D034841:Abdominal Cavity / Q000502:physiology*; D000328:Adult; D017081:Cholecystectomy, Laparoscopic; D005260:Female; D005753:Gastric Mucosa / Q000502:physiology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D011027:Pneumoperitoneum / Q000503:physiopathology*; D011312:Pressure / Q000009:adverse effects*