Use of low molecular weight heparin in cats: 57 cases (1999-2003).
OBJECTIVE
To determine duration of administration, complications, and frequency of aortic thromboembolism associated with administration of low molecular weight heparin (dalteparin) in cats.


METHODS
Retrospective study.


METHODS
57 cats treated with dalteparin


METHODS
Data were recorded from the medical records of cats treated with dalteparin, and owners were contacted by telephone for information regarding ease of administration and possible adverse effects.


RESULTS
Dalteparin was easily administered by owners. Median dose was 99 U/kg (45 U/lb) once or twice daily. Bleeding complications were infrequent. Of 43 cats with cardiomyopathy that received owner-administered dalteparin for a median follow-up time of 172 days, 8 cats developed documented or possible arterial thromboembolism.


CONCLUSIONS
Dalteparin was easily administered by owners and was well tolerated by cats. Whether dalteparin administration can reduce the frequency or severity of arterial thromboembolism is not yet known.
Smith
Caren E
CE
Department of Clinical Sciences, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA.
Rozanski
Elizabeth A
EA
Freeman
Lisa M
LM
Brown
Donald J
DJ
Goodman
Jennifer S
JS
Rush
John E
JE
D000818:Animals; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use*; D001777:Blood Coagulation / Q000187:drug effects; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000009:adverse effects / Q000627:therapeutic use*; D007279:Injections, Subcutaneous / Q000662:veterinary; D008297:Male; D012189:Retrospective Studies; D013923:Thromboembolism / Q000188:drug therapy / Q000662:veterinary*; D016896:Treatment Outcome
D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight