[Total pharyngolaryngoesophagectomy and gastric pull-up: an evaluation of 10 cases].
OBJECTIVE
We evaluated the patients who underwent total pharyngolaryngoesophagectomy (T-PLE) and gastric pull-up (GPU) for hypopharyngeal tumors extending to the cervical esophagus.


METHODS
Ten patients (8 females, 2 males; mean age 50 years; range 39 to 60 years) were treated with T-PLE and GPU, total thyroidectomy, and bilateral neck dissection including zone VI. Histopathologic diagnoses were squamous cell carcinoma (n = 8), basaloid squamous cell carcinoma (n = 1), and adenoid cystic carcinoma (n = 1). Clinical stage, tumor stage, and nodal status were as follows: eight patients IVA, two patients III; eight patients T4a, two patients T3; seven patients N+ (6 N2, 1 N1), three patients N0.


RESULTS
Three patients (30%) died within a month after surgery. Two patients were alive after the seventh and first postoperative years, respectively. The remaining five patients died because of causes related (n = 3) to or unrelated (n = 2) to carcinoma. Survival was 20% for one year, and 14.3% for five years. Histopathologically, surgical margins were free of tumor in nine cases. The mean time to the initiation of oral feeding was nine days (range 4 to 14 days), and the mean hospital stay was 23 days (range 12 to 36 days).


CONCLUSIONS
Early initiation of oral feeding and relatively short hospitalization periods make T-PLE and GPU an appropriate palliative procedure, increasing the quality of life for many patients.
Erişen
Levent
L
Uludağ Universitesi Tip Fakültesi, 'Kulak Burun Boğaz Anabilim Dali, Ankara. lerisen@uludag.edu.tr
Coşkun
Hakan
H
Korun
Nusret
N
Gebitekin
Cengiz
C
Basut
Oğuz
O
D000328:Adult; D003528:Carcinoma, Adenoid Cystic / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D016629:Esophagectomy / Q000379:methods*; D005260:Female; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010611:Pharyngectomy; D016019:Survival Analysis; D016896:Treatment Outcome