title: Antimicrobial screening and quantitative determination of benzoic acid derivative of Gomphrena celosioides by TLC-densitometry.
abstract: The antimicrobial activity of ethanolic extract and pure compounds of Gomphrena celosioides have been screened by Kirby-Bauer method. Quantitative determination of 4-hydroxy-3-methoxy-benzoic acid in stems, leaves, flowers and roots was established by TLC-densitometry. Results showed significant activity against Staphylococcus aureus and Salmonella typhi. There were no significant differences in the determined benzoic acid derivative.
authors.affiliation: Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, 14040-020 Ribeirão Preto, São Paulo, Brazil.
authors.forename: Rute Mendonça Xavier
authors.initials: RM
authors.lastname: de Moura
authors.forename: Paulo Sérgio
authors.initials: PS
authors.lastname: Pereira
authors.forename: Ana Helena
authors.initials: AH
authors.lastname: Januário
authors.forename: Suzelei de Castro
authors.initials: Sde C
authors.lastname: França
authors.forename: Diones Aparecida
authors.initials: DA
authors.lastname: Dias
mesh_terms: D027703:Amaranthaceae; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D019817:Benzoic Acid / Q000302:isolation & purification* / Q000494:pharmacology; D002855:Chromatography, Thin Layer / Q000379:methods; D003720:Densitometry / Q000379:methods; D004353:Drug Evaluation, Preclinical / Q000379:methods; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology; D018514:Plant Structures; D012485:Salmonella typhi / Q000187:drug effects / Q000502:physiology
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D019817:Benzoic Acid