title: Oxidosqualene cyclase second-sphere residues profoundly influence the product profile.
authors.affiliation: Department of Chemistry, Rice University, 6100 S. Main Street, Houston, TX 77005, USA.
authors.forename: Silvia
authors.initials: S
authors.lastname: Lodeiro
authors.forename: Michael J R
authors.initials: MJ
authors.lastname: Segura
authors.forename: Martin
authors.initials: M
authors.lastname: Stahl
authors.forename: Tanja
authors.initials: T
authors.lastname: Schulz-Gasch
authors.forename: Seiichi P T
authors.initials: SP
authors.lastname: Matsuda
mesh_terms: D002384:Catalysis; D019751:Intramolecular Transferases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D008958:Models, Molecular; D008968:Molecular Conformation; D016296:Mutagenesis; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000235:genetics
chemical_list: D019751:Intramolecular Transferases; C021924:lanosterol synthase; C021923:cycloartenol synthase