title: Overnight orthokeratology: refractive and corneal recovery after discontinuation of reverse-geometry lenses.
abstract: OBJECTIVE
  To determine the refractive and corneal topographic recovery after the use of reverse-geometry contact lenses for overnight orthokeratology.
  
  
  METHODS
  Both eyes of 15 subjects were fitted with reverse-geometry contact lenses that were worn by the subjects for 1 month. Uncorrected visual acuity, refractive correction (sphere and spherical equivalent), corneal curvature, and corneal thickness were measured during this time and for 2 weeks after discontinuation of lens wear.
  
  
  RESULTS
  Ten subjects completed the investigation. Uncorrected visual acuity, refractive correction, and corneal curvature had changed significantly (P = 0.01) after 1 month of lens wear. By the end of 1 month, central corneal thickness was significantly thinner than the baseline value (P = 0.01), but it recovered fully after one night of no lens wear. Recovery of corneal curvature was complete 1 week after lens wear was discontinued. Refractive correction and binocular uncorrected visual acuity recovered fully after 2 weeks. Monocular uncorrected visual acuity remained significantly (P = 0.01) different from baseline acuity 2 weeks after lens discontinuation.
  
  
  CONCLUSIONS
  Full effect of overnight orthokeratology in low myopes is achieved within 1 week of initiating use of reverse-geometry lenses. Recovery after short-term use of reverse-geometry lenses is rapid for corneal thickness and corneal curvature. Refractive correction and binocular uncorrected visual acuity recovered fully after 2 weeks. Monocular uncorrected visual acuity was the slowest to recover and had not achieved full recovery after 2 weeks.
authors.affiliation: Borish Center for Ophthalmic Research, School of Optometry, Indiana University, Bloomington, IN 47405, USA. sonip@indiana.edu
authors.forename: P Sarita
authors.initials: PS
authors.lastname: Soni
authors.forename: Tracy T
authors.initials: TT
authors.lastname: Nguyen
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Bonanno
mesh_terms: D000328:Adult; D003261:Contact Lenses; D003315:Cornea / Q000503:physiopathology*; D019781:Corneal Topography; D005260:Female; D006801:Humans; D008297:Male; D009216:Myopia / Q000503:physiopathology / Q000628:therapy*; D011474:Prosthesis Design; D013997:Time Factors; D014792:Visual Acuity / Q000502:physiology