Nonspecific interstitial pneumonia with poor prognosis associated with amyopathic dermatomyositis.
Amyopathic dermatomyositis (ADM) is a clinical subtype of dermatomyositis, characterized by the lack of motor weakness and the presence of normal muscle enzyme levels. ADM is sometimes accompanied by interstitial pneumonia that shows a rapid progressive course associated with a poor prognosis. We report a 49-year-old patient who presented with nonspecific interstitial pneumonia (NSIP) associated with ADM. The patient failed to respond to prednisolone and immunosuppressive therapy and died. Although idiopathic NSIP is known to have a better prognosis, NSIP in ADM could be a fatal disease. Therefore, we should appropriately treat interstitial pneumonia in ADM even if it is NSIP.
Sakamoto
Noriho
N
Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki.
Mukae
Hiroshi
H
Fujii
Takeshi
T
Yoshioka
Sumako
S
Kakugawa
Tomoyuki
T
Yamaguchi
Hiroyuki
H
Hayashi
Tomayoshi
T
Kohno
Shigeru
S
D003882:Dermatomyositis / Q000150:complications* / Q000175:diagnosis; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D011379:Prognosis; D011859:Radiography
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D011239:Prednisolone