Primary carcinoid tumor of the bilateral testis associated with carcinoid syndrome.
Carcinoid tumors derived from neuroendocrine cells can release serotonin and other vasoactive substances into the systemic circulation, resulting in carcinoid syndrome. Testicular carcinoid, a rare disease accounting for less than 1% of all testicular neoplasms, rarely manifests symptoms of carcinoid syndrome. We describe a case of carcinoid syndrome arising from a primary testicular carcinoid tumor. A 21-year-old male patient presented with facial flushing and diarrhea for 5 years. He had an enlarged left testis and a 1-cm, ill-defined, hard, non-tender mass in his right testis. His 24 h urinary excretion of 5-hydroxyindoleacetic acid was elevated (16.1 mg/day). Somatostatin receptor scintigraphy correlated with carcinoid tumor in both testes. Following bilateral orchiectomy, the patient's facial flushing and diarrhea disappeared.
Son
Hyun-Young
HY
Department of Internal Medicine, University of Ulsan College of Medicine, Seoul, Korea.
Ra
Seung-Won
SW
Jeong
Jin-Ook
JO
Koh
Eun-Hee
EH
Lee
Hyang-Im
HI
Koh
Jung-Min
JM
Kim
Won-Bae
WB
Park
Joong-Yeol
JY
Shong
Young-Kee
YK
Lee
Ki-Up
KU
Kim
Ghi-Su
GS
Kim
Min-Seon
MS
D000328:Adult; D002276:Carcinoid Tumor / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000652:urine; D008297:Male; D008303:Malignant Carcinoid Syndrome / Q000209:etiology*; D009919:Orchiectomy; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000601:surgery
D006897:Hydroxyindoleacetic Acid