title: A milligram of gluten a day keeps the mucosal recovery away: a case report.
abstract: In recent years it has been suggested that patients with celiac disease can be adequately followed up on the basis of merely clinical and serological response to a gluten-free diet. Thus, a duodenal biopsy some months after commencement of a gluten-free diet would no longer be necessary. We report here the case of a celiac patient in whom the ingestion of a milligram of gluten every day for 2 years prevented histological recovery in spite of satisfactory clinical and serological response. The literature regarding the minimal amount of gluten that could be harmless to celiac patients is reviewed.
authors.affiliation: IRCCS Policlinico S Matteo, University of Pavia, Italy.
authors.forename: Federico
authors.initials: F
authors.lastname: Biagi
authors.forename: Jonia
authors.initials: J
authors.lastname: Campanella
authors.forename: Susi
authors.initials: S
authors.lastname: Martucci
authors.forename: Donatella
authors.initials: D
authors.lastname: Pezzimenti
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Ciclitira
authors.forename: Heather J
authors.initials: HJ
authors.lastname: Ellis
authors.forename: Gino R
authors.initials: GR
authors.lastname: Corazza
mesh_terms: D000328:Adult; D002446:Celiac Disease / Q000178:diet therapy* / Q000473:pathology*; D018753:Diet, Protein-Restricted / Q000379:methods; D004305:Dose-Response Relationship, Drug; D005260:Female; D005983:Glutens / Q000008:administration & dosage*; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology*; D010349:Patient Compliance; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D005983:Glutens