[Taurine effects on background impulse activity of the internal geniculate body neurons and mesencephalic inferior tubers of white rats].
Microelectrophysiological and computer techniques were used in the study of background impulse activity (BIA) of the internal geniculate body (IGB) neurons and mesencephalic inferior tubers (MIT) of white rats. Definite differences were found in BIA by regularity, dynamic types and modality of interimpulse histograms. Mean frequency of MIT neuron discharges was 16-17 Hz and was about 3 times higher than in neurons of the IGB. Intraperitoneal injection of taurin noticeably suppressed neuronal activity in both nuclei. The drug reduced mean frequency of background impulse discharges both in MIT and IGB. Thus, taurin produces primarily suppressing modulating effect on neuronal activity of IGB and MIT.
Khanbabian
M V
MV
Khudaberdian
D N
DN
Khanbabian
A M
AM
Arutiunian
A G
AG
Gevorkian
A P
AP
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D017626:Cochlear Nucleus / Q000187:drug effects* / Q000502:physiology; D003201:Computers; D003627:Data Interpretation, Statistical; D004594:Electrophysiology; D005829:Geniculate Bodies / Q000187:drug effects* / Q000502:physiology*; D007274:Injections, Intraperitoneal; D008839:Microelectrodes; D009430:Neural Analyzers / Q000502:physiology; D009474:Neurons / Q000187:drug effects* / Q000502:physiology*; D051381:Rats; D013654:Taurine / Q000008:administration & dosage / Q000494:pharmacology*; D003336:Tectum Mesencephali / Q000187:drug effects* / Q000502:physiology*
D013654:Taurine