title: Breast cancer bone metastasis in femur: surgical considerations and reconstruction with Long Gamma Nail.
abstract: OBJECTIVE
  The femur is the most common long bone involved in metastatic breast cancer. Several studies have been published on the surgical management of metastatic disease of the femur. However, only few studies have been published specifically on the outcomes following reconstruction of femoral metastasis from breast cancer using a third generation intramedullary nail. The aim of this study is to review the outcomes after intramedullary surgical stabilization of femoral metastases from breast cancer. This is often associated with significant bone destruction.
  
  
  METHODS
  A retrospective study of 18 femoral metastatic lesions in 15 patients treated with a Long Gamma Nail over a 6-year period was carried out. Pain relief, mobilization status and implant related complications were the main outcome measures analyzed.
  
  
  RESULTS
  Thirteen out of 15 patients had complete pain relief and all patients regained their preoperative mobilization status with or without walking aids. There were no implant failures or perioperative deaths. Four (26%) patients developed minor complications. Ten patients died with an average survival of 9 months and five patients are alive with an average survival of 32 months.
  
  
  CONCLUSIONS
  Stabilization of femoral metastases due to breast cancer with Long Gamma Nail is a safe and effective method with acceptable risks.
authors.affiliation: Base Hospital, Derbyshire Royal Infirmary, Derby, UK. srsamsani@aol.com
authors.forename: S R
authors.initials: SR
authors.lastname: Samsani
authors.forename: V
authors.initials: V
authors.lastname: Panikkar
authors.forename: K M
authors.initials: KM
authors.lastname: Venu
authors.forename: D
authors.initials: D
authors.lastname: Georgiannos
authors.forename: D
authors.initials: D
authors.lastname: Calthorpe
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001858:Bone Nails; D001943:Breast Neoplasms / Q000473:pathology*; D005266:Femoral Neoplasms / Q000556:secondary* / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D010146:Pain / Q000209:etiology / Q000517:prevention & control; D011183:Postoperative Complications; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome