Tichocarpols A and B, two novel phenylpropanoids with feeding-deterrent activity from the red alga Tichocarpus crinitus.
Two novel phenylpropanoic acid derivatives, tichocarpol A (1) and tichocarpol B (2), were isolated along with floridoside and isethionic acid from the red alga Tichocarpus crinitus. The structures of these novel metabolites were elucidated using a combination of spectral (1D and 2D NMR techniques and ESIMS) and chemical methods. Compounds 1, 2, and floridoside exhibited feeding-deterrent activity against the sea urchin Strongylocentrotus intermedius.
Ishii
Takahiro
T
Division of Material Science, Graduate School of Environmental Earth Science, Hokkaido University, Sapporo 060-0810, Japan.
Okino
Tatsufumi
T
Suzuki
Minoru
M
Machiguchi
Yuji
Y
D000818:Animals; D005247:Feeding Behavior / Q000187:drug effects*; D007564:Japan; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010666:Phenylpropionates / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000461:Rhodophyta / Q000737:chemistry*; D012617:Sea Urchins / Q000187:drug effects*
D010666:Phenylpropionates; C493746:tichocarpol A; C493747:tichocarpol B