Enzymatic formation of multiple triterpenes by mutation of tyrosine 510 of the oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae.
Wu
Tung-Kung
TK
Department of Biological Science and Technology, Center for Interdisciplinary Molecular Science, National Chiao Tung University, 300, Hsin-Chu, Taiwan, Republic of China. tkwmll@mail.nctu.edu.tw
Chang
Cheng-Hsiang
CH
D019751:Intramolecular Transferases / Q000235:genetics / Q000378:metabolism*; D016296:Mutagenesis; D009154:Mutation / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000201:enzymology* / Q000235:genetics; D014315:Triterpenes / Q000378:metabolism*; D014443:Tyrosine / Q000737:chemistry* / Q000235:genetics
D014315:Triterpenes; D014443:Tyrosine; D019751:Intramolecular Transferases; C021924:lanosterol synthase