Chemotaxonomic relevance of cardenolides in Urginea fugax.
In a chemotaxonomic approach the investigation of a methanolic extract of bulbs of Urginea fugax (MORIS) STEINH. resulted in the detection of several cardenolides. The structure of a novel compound, named fugaxin (1), was established as 12alpha,14beta-dihydroxy-2alpha,3beta-(tetrahydro-3',5'-dihydroxy-4'-methoxy-6'-methyl-2H-pyran-2',4'-diylbisoxy)-card-4,20-dienolide by extensive NMR spectroscopic studies including 2D-NMR techniques (COSY, HSQC, HMQC) and selective 1D experiments (NOE, TOCSY) as well as HR-ESI-MS. The chemotaxonomic relevance of the occurrence of cardenolides in the genus Urginea is discussed.
Krenn
Liselotte
L
Institute of Pharmacognosy, University of Vienna, PharmaCenterVienna, Althanstrasse 14, A-1090 Vienna, Austria. liselotte.krenn@univie.ac.at
Hüfner
Antje
A
Kastenhuber
Anna
A
Speta
Franz
F
D002298:Cardenolides / Q000737:chemistry*; D031448:Drimia / Q000737:chemistry* / Q000145:classification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry
C494931:12alpha,14beta-dihydroxy-2alpha,3beta-(tetrahydro-3',5'-dihydroxy-4'-methoxy-6'-methyl-2H-pyran-2',4'-diylbisoxy)-card-4,20-dienolid; D002298:Cardenolides