title: [Microbial keratitis following laser in situ keratomileusis. Prevention, differential diagnosis, and therapy].
abstract: Laser in situ keratomileusis (LASIK) is an effective option and currently one of the most commonly applied surgical techniques in the correction of refractive errors such as myopia, hyperopia, and astigmatism. In contrast to photorefractive keratectomy, it maintains the integrity of Bowman's membrane and the epithelium leading to faster visual rehabilitation as well as less pain and discomfort. Nevertheless, following LASIK the stroma is exposed to infectious organisms. Sight-threatening complications after LASIK are reported to be as rare as 1 in 1000 procedures. However, any infectious keratitis remains potentially devastating. Reports about infectious keratitis following LASIK have increasingly surfaced in recent years. We present a review of the literature on microbial keratitis and present our own cases and recommendations for possible prophylaxis and therapy.
authors.affiliation: Augenklinik, Universität, Mainz. tehrani@augen.klinik.uni-mainz.de
authors.forename: M
authors.initials: M
authors.lastname: Tehrani
authors.forename: H B
authors.initials: HB
authors.lastname: Dick
authors.forename: G
authors.initials: G
authors.lastname: Daeschlein
authors.forename: A
authors.initials: A
authors.lastname: Kramer
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D015817:Eye Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology / Q000517:prevention & control; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology / Q000517:prevention & control; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology / Q000517:prevention & control; D006801:Humans; D015994:Incidence; D007634:Keratitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology* / Q000517:prevention & control; D016849:Keratitis, Herpetic / Q000175:diagnosis / Q000209:etiology; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D011182:Postoperative Care; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy / Q000517:prevention & control; D011300:Preoperative Care; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents