title: Low perioperative mortality for cardiac surgery in octogenarians.
abstract: OBJECTIVE
  The number of cardiac operations in octogenarians is steadily increasing. A review of personal 4 years' experience is made in order to identify which variables are associated to a poor prognosis in this high risk population.
  
  
  METHODS
  Perioperative variables and short-term outcome of 109 consecutive octogenarians were prospectively collected in a database. Data were analysed with descriptive statistics. Univariate and multivariate analyses were performed to identify preoperative risk factors for prolonged mechanical ventilation and ICU stay.
  
  
  RESULTS
  The 109 octogenarians represented 1.8% of the 4 940 cardiac operations performed at our University Teaching Hospital in the period January 1998-June 2001: 94 patients had comorbidities (86%); 46 underwent valve surgery (42%), 38 had coronary artery bypass grafting surgery (36%), and combined procedures or aortic arch replacement were performed in 25 patients (22%). Two patients died (1.8%). Postoperative complications included: myocardial infarction (10 patients, 9%), stroke (6 patients, 5%), renal replacement therapy (1 patient, 1%). Sixty nine patients (63%) had an uneventful perioperative period (63%). On a multivariate analysis, cardiopulmonary bypass (CPB) time was associated with prolonged intubation and ICU stay; mitral pathology predicted prolonged intubation while previous cardiac surgery was associated with prolonged ICU stay.
  
  
  CONCLUSIONS
  The 109 octogenarians studied had an excellent course in the immediate postoperative period. Therefore, on the basis of personal experience cardiac surgery could be safely performed in octogenarians.
authors.affiliation: Department of Cardiovascular Anesthesia, IRCCS San Raffaele Hospital, Vita-Salute University, Milan, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Zangrillo
authors.forename: D
authors.initials: D
authors.lastname: Sparicio
authors.forename: M
authors.initials: M
authors.lastname: Crivellari
authors.forename: G
authors.initials: G
authors.lastname: Aletti
authors.forename: T
authors.initials: T
authors.lastname: Bove
authors.forename: D
authors.initials: D
authors.lastname: Mamo
authors.forename: E
authors.initials: E
authors.lastname: Bignami
authors.forename: G
authors.initials: G
authors.lastname: Marino
authors.forename: G
authors.initials: G
authors.lastname: Landoni
mesh_terms: D000368:Aged; D000369:Aged, 80 and over / Q000502:physiology*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000401:mortality*; D005260:Female; D006801:Humans; D008297:Male; D019990:Perioperative Care / Q000401:mortality*; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome