title: [Cross-cultural adaptation of a questionnaire for measuring the quality of life of patients taking oral anticoagulants].
abstract: OBJECTIVE
  To adapt to Spanish culture and language a questionnaire developed to evaluate the quality of life of patients taking oral anticoagulation treatment (OAT) and to measure its validity.
  
  
  METHODS
  A descriptive observation study to validate an instrument to measure health-related quality of life.
  
  
  METHODS
  Primary and specialist care.
  
  
  METHODS
  225 patients, all the patients at our centre who were on OAT and a consecutive sample of patients on OAT from the referral hospital's haemotology service.
  
  
  METHODS
  Direct translation, back-translation, and pilot study. Factor analysis and item-dimension grouping, internal consistency analysis and analysis of the item-total correlation of the definitive version of the questionnaire in Spanish.
  
  
  RESULTS
  Mean age was 65 (SD=13 years); 51% were women; 45.8% were monitored in PC. Validity study: factor analysis extracted 5 factors that explained 41.62% of total variance value and obtained a grouping different from the original; Cronbach's alpha was .82 overall and ran from .56 to .74 in the various dimensions; and item-total correlation analysis had statistically significant values, except for question 29.
  
  
  CONCLUSIONS
  After adaptation to Spanish culture and language of a questionnaire developed to evaluate the quality of life of patients taking OAT, it was found to be a useful instrument, valid for use in our milieu.
authors.affiliation: Centro de Salud San Blas, Area 10 IMSALUD, Parla, Madrid, Spain. rsanchez.gapm10@salud.madrid.org
authors.forename: R
authors.initials: R
authors.lastname: Sánchez González
authors.forename: M
authors.initials: M
authors.lastname: Yanes Baonza
authors.forename: A
authors.initials: A
authors.lastname: Cabrera Majada
authors.forename: J M
authors.initials: JM
authors.lastname: Ferrer García-Borrás
authors.forename: R
authors.initials: R
authors.lastname: Alvarez Nido
authors.forename: E
authors.initials: E
authors.lastname: Barrera Linares
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000008:administration & dosage* / Q000009:adverse effects; D003466:Cultural Characteristics; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction / Q000706:statistics & numerical data*; D011788:Quality of Life / Q000523:psychology*; D011795:Surveys and Questionnaires; D014177:Translations
chemical_list: D000925:Anticoagulants