title: [The effectiveness of latanoprost for the treatment of pediatric glaucoma].
abstract: Latanoprost is a prostaglandin F2alpha analog that reduces intraocular pressure by 20-40% in adults with open-angle glaucoma. The efficacy and safety of this drug in children has not been widely reported. In our study we evaluated the effect of latanoprost in 14 children aged 12-18 years (mean 15 years): 10 patients with glaucoma juvenile (I group); 2 patients with secondary glaucoma because of uveitis recidivans and 2 patients with aniridia and albinismus (II group). In the I group the average IOP decrement was 9 mmHg or 36.5% (range 29-44%). In the II group the average IOP decrement was 6.5 mmHg or 23.5% (range 11-33%). In one child with aniridia after one year of treatment IOL rose again to 26 mmHg and antiglaucomatous surgery was necessary. Ocular side effects in children of latanoprost are mild.
authors.affiliation: Kliniki Okulistyki Dzieciecej Akademii Medycznej w Białymstoku.
authors.forename: Beata
authors.initials: B
authors.lastname: Urban
authors.forename: Alina
authors.initials: A
authors.lastname: Bakunowicz-Lazarczyk
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Mrugacz
authors.forename: Monika
authors.initials: M
authors.lastname: Oziebło-Kupczyk
mesh_terms: D000293:Adolescent; D000959:Antihypertensive Agents / Q000627:therapeutic use; D002648:Child; D005260:Female; D005901:Glaucoma / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D000077338:Latanoprost; D008297:Male; D011461:Prostaglandins F, Synthetic / Q000627:therapeutic use*; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents; D011461:Prostaglandins F, Synthetic; D000077338:Latanoprost