[Surgical treatment of multiresistant lung tuberculosis].
Drug resistance has become a major problem in the treatment of tuberculosis. Pulmonary resection in combination with chemotherapy appears to be an effective measure for the treatment of multi-drug resistant pulmonary tuberculosis. A retrospective review was performed of the medical and laboratory findings of 28 patients with multi-drug resistant tuberculosis who underwent pulmonary resection for pulmonary tuberculosis between January 1990 and December 2000 at La Maria Hospital, Medellín. Twenty-one of them had medical therapy before surgery; 14 patients underwent upper lobectomy and 10 patients pneumonectomy). The AFB negative sputum conversion rate was 88.9% (25/27) after surgery, during an average of 6 weeks. Bacteriological relapses were confirmed in 6 of 27, 4 of these 6 had AFB negative sputum. Twenty-eight patients had medical therapy after surgery. For selected patients, pulmonary resection in combination with chemotherapy should be considered an effective measure for treatment of multi-drug resistant pulmonary tuberculosis.
Tobón
Angela
A
Hospital La María, Medellín, Colombia.
Paniagua
Lizeth
L
Henao
Marcela
M
Arcila
Vivian
V
Maya
José
J
Bedoya
Fernando
F
Muñoz
Bernardo
B
D000293:Adolescent; D000328:Adult; D000368:Aged; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000601:surgery*