Ferrocenyl monophosphine ligands: synthesis and applications in the Suzuki-Miyaura coupling of aryl chlorides.
Ferrocenyl monophosphine ligands have been developed by a method based on palladium-catalyzed Suzuki-Miyaura coupling. The modular procedure creates a rapid synthesis of phosphines with diverse properties. The electron-rich phosphines have been successfully applied to the Suzuki-Miyaura coupling of activated and deactivated aryl chlorides, with low catalyst loading being feasible in the synthesis of tris-ortho-substituted biaryls.
Baillie
Colin
C
Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, UK.
Zhang
Lixin
L
Xiao
Jianliang
J