Cyclopentanoid cyanohydrin glucosides and amides of Lindackeria dentata.
A mixture of cyanogenic glucosides epivolkenin and taraktophyllin, 1,4-dihydroxy-2-cyclopentenecarboxamide, and uridine were isolated from leaves of Lindackeria dentata (Flacourtiaceae). Another cyclopentanoid amide, (1 R,4 S,5 R)-1,4,5-trihydroxy-2-cyclopentenecarboxamide, was synthesized in two steps from gynocardin, and shown to have the same relative configuration as a partially identified amide previously isolated from L. dentata bark.
Jaroszewski
Jerzy W
JW
Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, Copenhagen, Denmark. jj@dfuni.dk
Ekpe
Patrick
P
Witt
Matthias
M
D000577:Amides / Q000737:chemistry; D005960:Glucosides / Q000737:chemistry; D006801:Humans; D009570:Nitriles / Q000737:chemistry; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves; D031308:Salicaceae
D000577:Amides; D005960:Glucosides; D009570:Nitriles; D010936:Plant Extracts; C430593:cyanohydrin