title: Moraxella catarrhalis coaggregates with Streptococcus pyogenes and modulates interactions of S. pyogenes with human epithelial cells.
abstract: The pathogens Streptococcus pyogenes and Moraxella catarrhalis colonize overlapping regions of the human nasopharynx. We have found that M. catarrhalis can dramatically increase S. pyogenes adherence to human epithelial cells and that species-specific coaggregation of these bacteria correlates with this enhanced adherence.
authors.affiliation: Department of Medical Microbiology and Immunology, Medical College of Ohio, Toledo 43614-5806, USA.
authors.forename: Eric R
authors.initials: ER
authors.lastname: Lafontaine
authors.forename: David
authors.initials: D
authors.lastname: Wall
authors.forename: Serena L
authors.initials: SL
authors.lastname: Vanlerberg
authors.forename: Haig
authors.initials: H
authors.lastname: Donabedian
authors.forename: Darren D
authors.initials: DD
authors.lastname: Sledjeski
mesh_terms: D001422:Bacterial Adhesion; D002460:Cell Line; D004847:Epithelial Cells / Q000382:microbiology*; D006801:Humans; D001936:Moraxella catarrhalis / Q000472:pathogenicity / Q000502:physiology*; D045828:Moraxellaceae Infections / Q000150:complications / Q000382:microbiology; D009305:Nasopharynx / Q000382:microbiology*; D013290:Streptococcal Infections / Q000150:complications / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000472:pathogenicity* / Q000502:physiology*