title: Central venous lines in neonates: a study of 2186 catheters.
abstract: OBJECTIVE
  To describe the use of percutaneously inserted silicone central venous lines (CVLs) in neonates at the Royal Brisbane and Women's Hospital, Australia.
  
  
  METHODS
  Data for all infants admitted from 1 January 1984 until 31 December 2002 who had a CVL were examined in the neonatal database, completed from paper records and patient charts where necessary. Autopsy reports of all babies who died with a catheter in place were reviewed.
  
  
  RESULTS
  There were 18,761 admissions, 2186 catheters in 1862 babies for a total of 35,159 days (median 14 days, range 1-99 days). The tip was in the right atrium for 1282 (58.6%) of the catheters. A total of 142 babies (7.6%) died with a CVL in place, 89 (4.8%) with the catheter tip in the right atrium. Thirty two of these 89 babies had an autopsy. No autopsies reported tension in the pericardium or milky fluid resembling intralipid. One case (0.05% of catheters) of non-lethal pericardial effusion occurred in a baby whose catheter was inappropriately left coiled in the right atrium. There were no cases of pleural effusion related to CVL use. Most (1523, 69.7%) were removed electively. Septicaemia occurred during the life of 116 catheters (5.3%).
  
  
  CONCLUSIONS
  This is the largest series of percutaneously inserted silicone central venous catheters reported. It illustrates the safety of these catheters in this context. It highlights the value of keeping prospective records on such catheters. Catheters with their tips in the right atrium and not coiled did not cause pericardial effusion. Strict insertion and management principles for CVLs should be adhered to.
authors.affiliation: Royal Brisbane and Women's Hospital, RBH Post Office, Brisbane, Queensland 4029, Australia. David_Cartwright@health.qld.gov.au
authors.forename: D W
authors.initials: DW
authors.lastname: Cartwright
mesh_terms: D001344:Autopsy; D001724:Birth Weight; D002405:Catheterization, Central Venous / Q000009:adverse effects / Q000295:instrumentation* / Q000706:statistics & numerical data; D006325:Heart Atria; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D008485:Medical Audit; D010490:Pericardial Effusion / Q000209:etiology; D010996:Pleural Effusion / Q000209:etiology; D018805:Sepsis / Q000382:microbiology; D012828:Silicones
chemical_list: D012828:Silicones