title: [Effects of weight-bearing exercise on bone metabolism in college women].
abstract: OBJECTIVE
  This study was done to identify the effects of weight-bearing exercise(WBE) on bone metabolism.
  
  
  METHODS
  WBE was performed for 12 weeks by healthy college women. Bone-related parameters were measured four times during this period by evaluating the immunoradiometric assay and enzyme immunoassay. Bone mineral densities (BMDs) were measured by dual energy x-ray absorptiometry before and after the WBE program. Data was analyzed using t-test, paired t-test, x2-test, and repeated measures ANOVA.
  
  
  RESULTS
  Osteocalcin, a bone formation marker, increased more in the experimental group than in the control group based on the interaction between time and group (F=3.29 p=.024). Little difference between the two groups was found for the other parameters: urinary deoxypyridinoline, insulin-like growth factor I, parathormone, serum calcium, and serum phosphorus without showing any time interaction between the groups. The femoral trochanter BMD rose in the experimental group while that of the control group fell, showing a significant difference for BMD (t=3.06 p=.005). However, there was no significant difference between the two groups for changes in BMD of the forearm, lumbar spine, femoral neck, and femoral ward's triangle.
  
  
  CONCLUSIONS
  These findings supported the WBE is beneficial for increasing bone formation in college women and long-term application is needed to substantiate the effects of WBE as a intervention in promotion of bone-health.
authors.affiliation: College of Nursing, University of Illinois at Chicago, USA.
authors.forename: Ju-Sung
authors.initials: JS
authors.lastname: Kim
authors.forename: Myung-Hee
authors.initials: MH
authors.lastname: Kim
authors.forename: Jae-Shin
authors.initials: JS
authors.lastname: Shin
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D015519:Bone Density; D015444:Exercise; D005260:Female; D006801:Humans; D015675:Osteocalcin / Q000097:blood
chemical_list: D015675:Osteocalcin