title: Trends in AIDS-defining and non-AIDS-defining malignancies among HIV-infected patients: 1989-2002.
abstract: In a comparison of rates of acquired immunodeficiency syndrome (AIDS)-defining malignancies (ADMs) for 1989-1996 versus 1997-2002, we found a decrease in ADMs (rate ratio, 0.31; P<.0001) and a significant increase in non-AIDS-defining malignancies (non-ADMs; rate ratio, 10.87; P<.0002). The mean CD4 cell count was lower among patients with ADMs than among those with non-ADMs. A longer duration of survival during highly active antiretroviral therapy might explain the increasing incidence of non-ADMs.
authors.affiliation: University of Alabama at Birmingham, USA. roger.bedimo@med.va.gov
authors.forename: Roger
authors.initials: R
authors.lastname: Bedimo
authors.forename: Ray Y
authors.initials: RY
authors.lastname: Chen
authors.forename: Neil A
authors.initials: NA
authors.lastname: Accortt
authors.forename: James L
authors.initials: JL
authors.lastname: Raper
authors.forename: Carol
authors.initials: C
authors.lastname: Linn
authors.forename: Jeroan J
authors.initials: JJ
authors.lastname: Allison
authors.forename: John
authors.initials: J
authors.lastname: Dubay
authors.forename: Michael S
authors.initials: MS
authors.lastname: Saag
authors.forename: Craig J
authors.initials: CJ
authors.lastname: Hoesley
mesh_terms: D000328:Adult; D000368:Aged; D019380:Anti-HIV Agents; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology* / Q000209:etiology*; D012307:Risk Factors
chemical_list: D019380:Anti-HIV Agents