title: [Lung cancer].
abstract: Tumor markers are defined as substances which are produced by cancer cells or non-cancer cells reactive to cancer cells, and reflect the cancer status, such as its presence, characteristics, and volume. Clinically, many tumor markers are useful not only to assess the presence/absence of cancer, the primary site, histology, stage, and recurrence, but also to monitor the anti-cancer therapy. Tumor markers for lung cancer play only supporting roles because of their limited sensitivity and specificity, but they are clinically essential to daily medical oncology. This review addresses 6 important tumor markers for lung cancer, namely, CEA, SLX, CYFRA, SCC, ProGRP, and NSE.
authors.affiliation: Division of Respiratory Disease, Saitama Cancer Center.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Komagata
authors.forename: Shuichi
authors.initials: S
authors.lastname: Yoneda
mesh_terms: D000951:Antigens, Neoplasm / Q000097:blood; D014408:Biomarkers, Tumor / Q000097:blood*; D002272:Carcinoembryonic Antigen / Q000097:blood; D006801:Humans; D007633:Keratins / Q000097:blood; D008175:Lung Neoplasms / Q000175:diagnosis*; D009844:Oligosaccharides / Q000097:blood; D010446:Peptide Fragments / Q000097:blood; D010455:Peptides / Q000097:blood; D010751:Phosphopyruvate Hydratase / Q000097:blood; D011994:Recombinant Proteins / Q000097:blood; D015843:Serpins / Q000097:blood; D000080506:Sialyl Lewis X Antigen
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D009844:Oligosaccharides; D010446:Peptide Fragments; D010455:Peptides; D011994:Recombinant Proteins; D015843:Serpins; D000080506:Sialyl Lewis X Antigen; C087079:pro-gastrin-releasing peptide (31-98); C051072:squamous cell carcinoma-related antigen; D007633:Keratins; D010751:Phosphopyruvate Hydratase