title: [Clinical observation of the pathological changes of axial length, corneal curvature and posterior segment wall of eyeball in eyes with high myopia].
abstract: OBJECTIVE
  To study the correlation between the characteristics of the morphologic changes in the wall of eyeball with high myopia and the visual function.
  
  
  METHODS
  The axial length, corneal curvature, etc., of 280 eyes in 140 cases (the diopter was from -6.25D to approximately -30.00D) were examined and the data were settled statistically.
  
  
  RESULTS
  (1) The corrected visual acuity in the patents with high myopia decreased apparently with the increase of diopter. The difference was significant (P < 0.001). (2) The axial length of anteroposterior diameter in 96.1% eyes increased, with which the diopter also increased. (3) 27.1% exophthalmos were forward. (4) There was no significant difference when compared the anterior surface corneal curvature with emmetropic eyes. (5) Posterior scleral staphyloma occurred in 80.7% eyes. (6) Optic nerve atrophy and optic disk atrophic arc spot occurred in 82.3% eyes. (7) The intraocular pressure increases in 5.3% eyes.
  
  
  CONCLUSIONS
  The severe damage to the visual function because of the pathological changes on the wall of eyeball is the main cause that vision can not be corrected in clinics.
authors.affiliation: Zongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou, China.
authors.forename: R
authors.initials: R
authors.lastname: Yu
authors.forename: Z
authors.initials: Z
authors.lastname: Guan
authors.forename: Z
authors.initials: Z
authors.lastname: Hu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003315:Cornea / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000150:complications / Q000473:pathology*; D009798:Ocular Hypertension / Q000209:etiology / Q000473:pathology; D009896:Optic Atrophy / Q000209:etiology / Q000473:pathology; D012029:Refraction, Ocular; D015422:Scleral Diseases / Q000209:etiology / Q000473:pathology; D014792:Visual Acuity; D055815:Young Adult