title: [A case of hypersensitivity pneumonitis caused by Lyophyllum karst].
abstract: A 52-year-old woman who has worked at factory to check pack Lyophyllum karst for six years consulted another doctor for dry cough as common cold. After a month, low grade fever, dyspnea on effort, and productive cough brought her to our hospital. Her chest radiographs showed multiple small nodular shadows and ground glass opacities in entire lung fields. Histopathological examination of transbronchial lung biopsy specimen revealed granuloma and thickening of alveolar septa with lymphocytes infiltration. She was admitted to our hospital for hypersensitivity pneumonitis and prescribed predonisorone 30 mg/day. Her symptoms and the finding of chest radiograph improved in two weeks. The precipitation antibodies to Lyophyllum karst were positive and the symptoms exacerbated by going to work. Those finding suggests that hypersensitivity pneumonitis in this case. After quitting her job, she has had no relapse by tapering steroids.
authors.affiliation: Department of Internal Medicine, Toyama Prefectural Central Hospital. tan@tch.pref.toyama.jp
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Taniguchi
authors.forename: Toshiro
authors.initials: T
authors.lastname: Miwa
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Abo
authors.forename: Hideki
authors.initials: H
authors.lastname: Miyazawa
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Noto
authors.forename: Akio
authors.initials: A
authors.lastname: Uchiyama
authors.forename: Atsuo
authors.initials: A
authors.lastname: Miwa
authors.forename: Saburo
authors.initials: S
authors.lastname: Izumi
mesh_terms: D000542:Alveolitis, Extrinsic Allergic / Q000276:immunology*; D001487:Basidiomycota / Q000276:immunology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009784:Occupational Diseases / Q000276:immunology*