title: Prevalence of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in an urban hospital in Dhaka, Bangladesh.
abstract: The prevalence of extended-spectrum beta-lactamases (ESBL)-producing organisms in an urban hospital in Dhaka City was assessed over a 10-month period. A double disk test was performed to detect ESBL-producing Escherichia coli and Klebsiella pneumoniae. 43.2% and 39.5% of E. coli and K. pneumoniae had ESBL phenotypes, respectively. The combination of augmentin with ceftazidime detected the most ESBL-producing E. coli (39.5%) while augmentin with ceftriaxone was the best combination for the detection of ESBL (31.6%) in K. pneumoniae.
authors.affiliation: Department of Immunology and Microbiology, National Healthcare Network, 69/M, Panthopath, Dhaka1205, Bangladesh.
authors.forename: M Mushfequr
authors.initials: MM
authors.lastname: Rahman
authors.forename: J Ashraful
authors.initials: JA
authors.lastname: Haq
authors.forename: M Akram
authors.initials: MA
authors.lastname: Hossain
authors.forename: Rosy
authors.initials: R
authors.lastname: Sultana
authors.forename: Faridul
authors.initials: F
authors.lastname: Islam
authors.forename: A H M Shafiqul
authors.initials: AH
authors.lastname: Islam
mesh_terms: D019980:Amoxicillin-Potassium Clavulanate Combination / Q000494:pharmacology; D001459:Bangladesh / Q000453:epidemiology; D002442:Ceftazidime / Q000494:pharmacology; D002443:Ceftriaxone / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D005260:Female; D006786:Hospitals, Urban; D006801:Humans; D007709:Klebsiella / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D008297:Male; D008826:Microbial Sensitivity Tests; D015995:Prevalence; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D019980:Amoxicillin-Potassium Clavulanate Combination; D002443:Ceftriaxone; D002442:Ceftazidime; D001618:beta-Lactamases