title: [18F-FDG positron emission tomography for mediastinal staging of lung cancer].
abstract: OBJECTIVE
  To evaluate the diagnostic value of (18)F-FDG positron emission tomography (PET) in mediastinal staging of lung cancer.
  
  
  METHODS
  A retrospective analysis of mediastinal staging was carried out in 41 cases of lung cancer by comparing the preoperative mediastinal FDG PET and CT findings with the pathological results.
  
  
  RESULTS
  According to the pathological results, 18 patients had mediastinal metastasis, 17 of whom were correctly identified by FDG PET, and 10 by CT. Of the other 23 patients without mediastinal metastasis pathologically, 22 were correctly diagnosed by FDG PET and 20 by CT. The sensitivity and accuracy for diagnosis of regional mediastinal lymph node metastasis with FDG PET were 94.4% and 95.1%, obviously higher than those of CT (55.6% and 73.2%, P<0.05).
  
  
  CONCLUSIONS
  FDG PET is a better alternative for mediastinal staging of lung cancer, specially for identification of small lymph node metastasis escaping detection by CT, to provide important evidence for clinical staging and treatment planning of lung cancer.
authors.affiliation: Diagnostic Imaging Centre, Southern Medical University, Guangzhou 510515, China.
authors.forename: Fang-ying
authors.initials: FY
authors.lastname: Liu
authors.forename: Xue-lin
authors.initials: XL
authors.lastname: Zhang
authors.forename: Jian-biao
authors.initials: JB
authors.lastname: Shang
authors.forename: Quan-shi
authors.initials: QS
authors.lastname: Wang
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000556:secondary; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000556:secondary; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D012189:Retrospective Studies
chemical_list: D019788:Fluorodeoxyglucose F18