title: Treating amiodarone-induced thyrotoxicosis with radioactive iodine.
abstract: Amiodarone use in the United States is increasing including a role in advanced cardiac life support protocols. There has been a significant increase in hypothyroidism, destructive thyroiditis (type II), and iodine-induced thyrotoxicosis (type I) with amiodarone. Preexisting thyroid disease and status of iodine intake can determine the nature of iodine-induced thyroid disease. Treating amiodarone-induced thyrotoxicosis (AIT) may include traditional antithyroid agents, glucocorticoids, and surgery. Usually, it is assumed the radioactive iodine uptake (RAIU) will be low, and this choice as a treatment modality is excluded at the initial visit. We report a satisfactory outcome in a patient with AIT using radioactive iodine. The role of radioactive iodine in treating AIT is reviewed
authors.affiliation: Department of Internal Medicine, East Tennessee State University, Johnson City, USA.
authors.forename: Said B
authors.initials: SB
authors.lastname: Iskandar
authors.forename: Richard M
authors.initials: RM
authors.lastname: Jordan
authors.forename: M Jordan
authors.initials: MJ
authors.lastname: Richard
authors.forename: Alan N
authors.initials: AN
authors.lastname: Peiris
mesh_terms: D000368:Aged; D000638:Amiodarone / Q000009:adverse effects* / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008297:Male; D018570:Risk Assessment; D012720:Severity of Illness Index; D013960:Thyroid Function Tests; D013971:Thyrotoxicosis / Q000139:chemically induced* / Q000532:radiotherapy*; D016896:Treatment Outcome
chemical_list: D007457:Iodine Radioisotopes; D000638:Amiodarone