Antimicrobial screening and quantitative determination of benzoic acid derivative of Gomphrena celosioides by TLC-densitometry.
The antimicrobial activity of ethanolic extract and pure compounds of Gomphrena celosioides have been screened by Kirby-Bauer method. Quantitative determination of 4-hydroxy-3-methoxy-benzoic acid in stems, leaves, flowers and roots was established by TLC-densitometry. Results showed significant activity against Staphylococcus aureus and Salmonella typhi. There were no significant differences in the determined benzoic acid derivative.
de Moura
Rute Mendonça Xavier
RM
Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, 14040-020 Ribeirão Preto, São Paulo, Brazil.
Pereira
Paulo Sérgio
PS
Januário
Ana Helena
AH
França
Suzelei de Castro
Sde C
Dias
Diones Aparecida
DA
D027703:Amaranthaceae; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D019817:Benzoic Acid / Q000302:isolation & purification* / Q000494:pharmacology; D002855:Chromatography, Thin Layer / Q000379:methods; D003720:Densitometry / Q000379:methods; D004353:Drug Evaluation, Preclinical / Q000379:methods; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology; D018514:Plant Structures; D012485:Salmonella typhi / Q000187:drug effects / Q000502:physiology
D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D019817:Benzoic Acid