title: [Body composition and left ventricular geometry].
abstract: Left ventricular mass and cardiac output are, particularly in obesity, correlated with fat free body mass. We assessed the relationship between ventricular geometry and fat body mass in treated hypertensives with or without normalization of blood pressure We investigated 175 patients (age: 57 +/- 15 years, M/F: 111/64, Mean blood pressure (MBP): 111 +/- 18 mmHg, BMI: 27.02 +/- 3.70 kg/m2: 20.3-39.6 kg/m2) with measure of body composition (impedancemetry Analycor2) and echographic left ventricular mass (adjusted to height2.7: mass2.7). Multiple correlation with adjustment to age and MBP were performed in men (M) and in women (W). Mass2.7 is correlated with fat mass percentage in men (R partial R: 5.6, p=0.02). LV diastolic diameter is correlated with fat free body mass while interventricular septum is correlated with fat body mass but only in men. In summary, in hypertensives not selected on BMI or BP, fat body mass is weakly correlated to ventricular wall thickness in men, probably mediated by sympathetic tone, while fat free body mass is related to ventricular volume in both gender probably through the water volume particularly in vascular bed. In conclusion, both components of body composition are differently, and weakly, linked to ventricular geometry in hypertensive patients.
authors.affiliation: Hôpital Manhès, Fleury-Mérogis.
authors.forename: B
authors.initials: B
authors.lastname: Pannier
authors.forename: J
authors.initials: J
authors.lastname: Raison
authors.forename: T I
authors.initials: TI
authors.lastname: Kondo
authors.forename: K
authors.initials: K
authors.lastname: Le Dudal
authors.forename: J
authors.initials: J
authors.lastname: Blacher
authors.forename: M
authors.initials: M
authors.lastname: Safar
mesh_terms: D000328:Adult; D000368:Aged; D000886:Anthropometry; D001794:Blood Pressure; D001823:Body Composition; D005260:Female; D006352:Heart Ventricles / Q000033:anatomy & histology*; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D020257:Ventricular Remodeling