Preparation of C-3,5-acyl furanoses via highly selective intramolecular acyl migration.
A practical synthesis of C-3,5-acyl furanose via a base-catalyzed, highly selective intramolecular acyl migration in alcohol solvents is reported.
Xu
Feng
F
Department of Process Research, Merck Research Laboratories, Rahway, New Jersey 07065, USA. feng_xu@merck.com
Simmons
Bryon
B
Savary
Kimberly
K
Yang
Chunhua
C
Reamer
Robert A
RA
D000215:Acylation; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D015394:Molecular Structure; D012266:Ribose / Q000031:analogs & derivatives* / Q000138:chemical synthesis*
D012266:Ribose