[Early form of toxoplasmosis with accompanying enlargement of lymph nodes].
The paper describes a case of a 42-year-old female presented rapidly increasing enlargement of lymph nodes. Initially it was believed to be an effect of proliferous systemic changes. The diagnostic procedures did not confirm the initial diagnosis but they evoked a lot of stress of the patient as well as her psychic discomfort resulting from a number of biopsies. Serological tests carried out in the further course of the diagnostic procedure showed that the increased nodular reaction should be attributed to Toxoplasma gondii invasion, which was indicated by the presence of IgM and IgA antibodies and low avidity of IgG. The early administration of specific treatment with spiramycin led to the regression of the clinical symptoms and gradual normalization of the serological test. The case is worth attention for several reasons: 1. it indicates that it is necessary to consider T. gondii infection in basic clinical practice, which is frequently ignored, 2. it illustrates the effectiveness of early specific treatment, 3. it demonstrates the importance of well selected and properly interpreted microbiological tests.
Małafiej
Eugeniusz
E
Zakład Mikrobiologii Klinicznej, Instytutu Centrum Zdrowia Matki Polki w Lodzi. euma@mazurek.man.lodz.pl
Spiewak
Ewa
E
Frankowska
Joanna
J
Maciejewska
Ewa
E
D000328:Adult; D000913:Antibodies, Protozoan / Q000097:blood*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008198:Lymph Nodes / Q000469:parasitology* / Q000473:pathology*; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology*
D000913:Antibodies, Protozoan; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M