Ruthenium-catalyzed hydrogenation of alkynylstannanes with migration of the stannyl group.
Molecular hydrogen adds to aliphatic and aromatic alkynylstannanes in the presence of a ruthenium catalyst, pushing the stannyl group to the adjacent carbon atom to give alpha-substituted vinylstannanes. This is the first achievement of hydrogenation of alkynylstannanes, which is applicable also to the deuteration affording precursors for an important class of deuterium-labeled compounds.
Shirakawa
Eiji
E
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan. shirakawa@kuchem.kyoto-u.ac.jp
Morita
Ryotaro
R
Tsuchimoto
Teruhisa
T
Kawakami
Yusuke
Y