Analysis of the reasons for accepting or declining participation in genetic research for breast cancer: a hospital-based population study.
The majority of a hospital-based population accepted to participate in a molecular screening project for familial breast cancer, giving their informed consent to blood sampling. Only 9.5% of patients declined to sign the consent form. Here we report the reasons for refusal and we critically review our methodological approach to obtain consent for a blood test for genetic research in a clinical setting.
Paradiso
Angelo
A
Laboratorio di Oncologia Sperimentale Clinica, Dipartimento di Oncologia Sperimentale, Istituto Oncologico di Bari, Italy. paradiso.io.bari@virgilio.it
Bruno
Michele
M
Cicoria
Onofrio
O
Digennaro
Maria
M
Longo
Salvatore
S
Rinaldi
Michele
M
Schittulli
Francesco
F
D001943:Breast Neoplasms / Q000235:genetics*; D005260:Female; D036281:Genetic Research; D006801:Humans; D007258:Informed Consent; D007297:Inpatients / Q000706:statistics & numerical data; D007558:Italy; D008403:Mass Screening; D010358:Patient Participation / Q000706:statistics & numerical data; D045808:Refusal to Participate / Q000706:statistics & numerical data