[Studies on extraction process of Fructus Schisandrae chinensis and Fructus Ligustri lucidi in gandening tablet].
OBJECTIVE
To optimize the combined extraction methods of Fructus Schisandrae Chinensis and Fructus Ligustri Lucidi.


METHODS
The extraction effects of three processes (SFE CO2, alcohol-extraction, water-extraction) were compared by the contents of deoxyschizandrin, the dried extraction yield and production feasibility.


RESULTS
The method of alcohol-extraction was the best of the three methods, and the extraction conditions were optimized by orthogonal design as follows: sixfold 90% alcohol for two times and each for one hour.


CONCLUSIONS
The extraction method is steady and feasible, which can be used for reference for the extraction process of Fructus Schisandrae Chinensis and Fructus Ligustri Lucidi.
Pan
Wu-Jiu
WJ
Department of Pharmacy, 302 Hospital of People's Liberation Army, Beijing 100039, China. panwujiu@hotmail.com
Xiao
Xiao-He
XH
Xiao
Xue
X
Yuan
Hai-Long
HL
Zhao
Yan-Ling
YL
D000438:Alcohols; D002626:Chemistry, Pharmaceutical / Q000379:methods; D025924:Chromatography, Supercritical Fluid; D034242:Cyclooctanes / Q000302:isolation & purification*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D005638:Fruit / Q000737:chemistry; D017705:Lignans / Q000302:isolation & purification*; D031659:Ligustrum / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D011083:Polycyclic Compounds / Q000302:isolation & purification*; D032141:Schisandra / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods*
D000438:Alcohols; D034242:Cyclooctanes; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D017705:Lignans; D011083:Polycyclic Compounds; C011105:schizandrin