Keratosis punctata palmoplantaris controlled with topical retinoids: a case report and review of the literature.
Keratosis punctata palmoplantaris (KPPP) is a rare genodermatosis with an autosomal-dominant pattern of inheritance. We report the case of a 61-year-old woman who presented with a long history of multiple symptomatic hyperkeratotic papules on the palms and soles. In addition, we review the literature and present the current classification of the heterogeneous group of punctate palmoplantar keratoses, the cutaneous and histologic findings, the differential diagnosis, the possible association with various anomalies including malignancies, and the various treatment options.
Kong
Michael S
MS
Regional Support Organization, San Diego, California 92136, USA. michael.kong@navy.mil
Harford
Robert
R
O'Neill
Jennifer T
JT
D000279:Administration, Cutaneous; D005260:Female; D005528:Foot / Q000473:pathology; D006225:Hand / Q000473:pathology; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics; D007641:Keratolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D008875:Middle Aged; D009539:Nicotinic Acids / Q000008:administration & dosage / Q000627:therapeutic use; D010375:Pedigree; D011379:Prognosis; D012176:Retinoids / Q000008:administration & dosage / Q000627:therapeutic use*; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D013997:Time Factors; D016896:Treatment Outcome
D007641:Keratolytic Agents; D009539:Nicotinic Acids; D012176:Retinoids; C086827:tazarotene