title: Primary carcinoid tumor of the bilateral testis associated with carcinoid syndrome.
abstract: Carcinoid tumors derived from neuroendocrine cells can release serotonin and other vasoactive substances into the systemic circulation, resulting in carcinoid syndrome. Testicular carcinoid, a rare disease accounting for less than 1% of all testicular neoplasms, rarely manifests symptoms of carcinoid syndrome. We describe a case of carcinoid syndrome arising from a primary testicular carcinoid tumor. A 21-year-old male patient presented with facial flushing and diarrhea for 5 years. He had an enlarged left testis and a 1-cm, ill-defined, hard, non-tender mass in his right testis. His 24 h urinary excretion of 5-hydroxyindoleacetic acid was elevated (16.1 mg/day). Somatostatin receptor scintigraphy correlated with carcinoid tumor in both testes. Following bilateral orchiectomy, the patient's facial flushing and diarrhea disappeared.
authors.affiliation: Department of Internal Medicine, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Hyun-Young
authors.initials: HY
authors.lastname: Son
authors.forename: Seung-Won
authors.initials: SW
authors.lastname: Ra
authors.forename: Jin-Ook
authors.initials: JO
authors.lastname: Jeong
authors.forename: Eun-Hee
authors.initials: EH
authors.lastname: Koh
authors.forename: Hyang-Im
authors.initials: HI
authors.lastname: Lee
authors.forename: Jung-Min
authors.initials: JM
authors.lastname: Koh
authors.forename: Won-Bae
authors.initials: WB
authors.lastname: Kim
authors.forename: Joong-Yeol
authors.initials: JY
authors.lastname: Park
authors.forename: Young-Kee
authors.initials: YK
authors.lastname: Shong
authors.forename: Ki-Up
authors.initials: KU
authors.lastname: Lee
authors.forename: Ghi-Su
authors.initials: GS
authors.lastname: Kim
authors.forename: Min-Seon
authors.initials: MS
authors.lastname: Kim
mesh_terms: D000328:Adult; D002276:Carcinoid Tumor / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000652:urine; D008297:Male; D008303:Malignant Carcinoid Syndrome / Q000209:etiology*; D009919:Orchiectomy; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000601:surgery
chemical_list: D006897:Hydroxyindoleacetic Acid