[Study on releasing rate of chrysophanol from Ruyi Jinhuang plaster].
OBJECTIVE
To study the releasing rate of chrysophanol from Ruyi Jinhuang plaster.


METHODS
Based on the detecting methods of releasing rate and residual dosage applied in (Pharmacopoeia of P. R. C) (2000 edition), the contents of chrysophanol were detected by HPLC.


RESULTS
Chrysophanol in Ruyi Jinhuang plaster could well be released from plaster and to form medicinal concentration gradient.


CONCLUSIONS
Chrysophanol in Ruyi-Jinhuang plaster can possibly be absorbed by skin.
Mao
Ping
P
Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Xu
Jia
J
Wu
Yun-Mine
YM
D000279:Administration, Cutaneous; D000818:Animals; D000880:Anthraquinones / Q000378:metabolism*; D030024:Curcuma / Q000737:chemistry; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000493:pharmacokinetics*; D005260:Female; D006168:Guinea Pigs; D008297:Male; D032102:Phellodendron / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D012250:Rheum / Q000737:chemistry; D012867:Skin / Q000378:metabolism; D012869:Skin Absorption
D000880:Anthraquinones; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C027113:chrysophanic acid