title: [The effect of mometasone furoate on mucociliary clearance in patients with perennial allergic rhinitis].
abstract: OBJECTIVE
  We investigated the effect of mometasone furoate on mucociliary clearance in patients with perennial allergic rhinitis.
  
  
  METHODS
  The study included 25 patients (16 females, 9 males; mean age 30 years; range 18 to 50 years) with perennial allergic rhinitis. Mometasone furoate (nasal spray) was administered at a dose of 2 puffs (100 microgr) to each nostril daily for a month. Mucociliary clearance was evaluated by the saccharin test before and after treatment.
  
  
  RESULTS
  The mean mucociliary clearance time was 6.89 +/- 0.64 minutes before the treatment and 7.18 +/- 0.54 minutes after the treatment. No significant delay in the mucociliary clearance was detected (p > 0.05). The mean mucociliary clearance time did not differ significantly between male and female patients (p > 0.05).
  
  
  CONCLUSIONS
  The results suggest that mometasone furoate do not affect mucociliary clearance in patients with perennial allergic rhinitis.
authors.affiliation: Mersin Universitesi, Tip Fakültesi Kulak Burun Boğaz Hastahiklari Anabilim Dali, Mersin. yavuzpata@mersin.edu.tr
authors.forename: Yavuz Selim
authors.initials: YS
authors.lastname: Pata
authors.forename: Yücel
authors.initials: Y
authors.lastname: Akbaş
authors.forename: Murat
authors.initials: M
authors.lastname: Unal
authors.forename: Kemal
authors.initials: K
authors.lastname: Görür
authors.forename: Cengiz
authors.initials: C
authors.lastname: Ozcan
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Vayisoğlu
mesh_terms: D000280:Administration, Inhalation; D000293:Adolescent; D000328:Adult; D018926:Anti-Allergic Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000068656:Mometasone Furoate; D009079:Mucociliary Clearance / Q000187:drug effects*; D009297:Nasal Mucosa / Q000187:drug effects; D011244:Pregnadienediols / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D018926:Anti-Allergic Agents; D011244:Pregnadienediols; D000068656:Mometasone Furoate