[Measurement of basal inhibin B level in Bulgarian women of the childbearing age].
OBJECTIVE
To establish mean and reference range of basal serum inhibin B levels in a group of healthy fertile Bulgarian women.


METHODS
The present report covers the results of 9 month's period in which sixty-five healthy fertile Bulgarian women, aged 20-40 years were selected to determinate a reference group of healthy fertile women with normal values of inhibin B. Blood samples were collected on early follicular phase of menstrual cycle (2-4 days). Inhibin B was analyzed in duplicate with the use of a double-antibody ELISA.


RESULTS
We established mean values of inhibin B 121.22 (+/- 45.04) pg/ml in a group of 65 healthy fertile Bulgarian women with mean 30.78 (+/- 3.94) years of age. The values of inhibin-B, which we obtained in the 5th percentile, was 33.15 pg/ml and in the 95th percentile was 190.75 pg/ml.


CONCLUSIONS
The measurement of inhibin B is a test easy for performance, with reference values for healthy fertile Bulgarian women between 33.15 pg/ml and 190.75 pg/ml.
Vladimirov
Ia
Ia
Tacheva
D
D
Kalinov
K
K
Manolov
V
V
Zakharieva
B
B
D000328:Adult; D015415:Biomarkers / Q000097:blood; D002031:Bulgaria; D005260:Female; D005298:Fertility / Q000502:physiology*; D006801:Humans; D007265:Inhibins / Q000097:blood*; D008597:Menstrual Cycle / Q000097:blood; D012016:Reference Values
D015415:Biomarkers; C422364:inhibin B; D007265:Inhibins