title: hp-DPI: Helicobacter pylori database of protein interactomes--embracing experimental and inferred interactions.
abstract: We implemented a statistical model into our protein interaction database for validation of two-hybrid assays of Helicobacter pylori, and prediction of putative protein interactions not yet discovered experimentally. To present the enormous amount of experimental and inferred protein interaction networking maps, the H.pylori Database of Protein Interactomes (hp-DPI) is developed with a succinct yet comprehensive visualization tool integrated with annotation from Genbank, GO, and KEGG. hp-DPI is first built with, but not limited to, H.pylori protein interactions and is expected to naturally include other organisms' protein interacting relationships in the future.
authors.affiliation: Division of Biostatistics and Bioinformatics, National Health Research Institutes, #128, Sec. 2 Yaun-Chio-Yun Rd, Taipei 115, Taiwan. cylin@nhri.org.tw
authors.forename: Chung-Yen
authors.initials: CY
authors.lastname: Lin
authors.forename: Chia-Ling
authors.initials: CL
authors.lastname: Chen
authors.forename: Chi-Shiang
authors.initials: CS
authors.lastname: Cho
authors.forename: Li-Ming
authors.initials: LM
authors.lastname: Wang
authors.forename: Chia-Ming
authors.initials: CM
authors.lastname: Chang
authors.forename: Pao-Yang
authors.initials: PY
authors.lastname: Chen
authors.forename: Chen-Zen
authors.initials: CZ
authors.lastname: Lo
authors.forename: Chao A
authors.initials: CA
authors.lastname: Hsiung
mesh_terms: D000465:Algorithms; D001426:Bacterial Proteins / Q000378:metabolism*; D003196:Computer Graphics; D003628:Database Management Systems; D030562:Databases, Protein; D004282:Documentation / Q000379:methods; D016480:Helicobacter pylori / Q000378:metabolism*; D016247:Information Storage and Retrieval / Q000379:methods*; D009862:Online Systems; D025941:Protein Interaction Mapping / Q000379:methods*; D014584:User-Computer Interface
chemical_list: D001426:Bacterial Proteins