title: Liver transplantation-associated hypercalcemia followed by acute renal dysfunction.
abstract: A 34-year-old woman with liver insufficiency due to glycogen storage disease III underwent a living spousal liver transplantation. Soon after the successful operation, moderate hypercalcemia along with hyperbilirubinemia emerged without clarified reasons. The hypercalcemia persisted for over a month despite calcitonin treatment and the serum calcium level surged to 13.2 mg/dl with albumin correction. Renal dysfunction was indicated by an acute increase in serum creatinine (approximately 0.8 to approximately 2.8 mg/ml), which was assumed to be hypercalcemia-induced and was effectively treated with bisphosphonate, pamidronate (30 mg, i.v.). Recent topics related to transplantation-associated hypercalcemia are discussed.
authors.affiliation: Department of Internal Medicine and Pathophysiology, Nagoya City University Graduate School of Medical Sciences, Nagoya.
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Shirasawa
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Nomura
authors.forename: Atsuhiro
authors.initials: A
authors.lastname: Yoshida
authors.forename: Takashi
authors.initials: T
authors.lastname: Hashimoto
authors.forename: Genjiro
authors.initials: G
authors.lastname: Kimura
authors.forename: Makoto
authors.initials: M
authors.lastname: Ito
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D000328:Adult; D005260:Female; D006010:Glycogen Storage Disease Type III / Q000150:complications; D006801:Humans; D006932:Hyperbilirubinemia / Q000209:etiology; D006934:Hypercalcemia / Q000188:drug therapy / Q000209:etiology*; D017093:Liver Failure / Q000209:etiology / Q000601:surgery; D016031:Liver Transplantation / Q000009:adverse effects*; D019520:Living Donors