title: Construction of building-blocks for polyether synthesis using sequential catalytic ring-closing enyne and cross metathesis.
abstract: Highly functionalised six- and seven-membered cyclic ethers bearing a variety of side chains have been synthesised using ring-closing enyne metathesis and subsequent cross metathesis of the intermediate diene; one-pot enyne and cross metathesis has also been accomplished, allowing ring construction and side chain introduction to be performed in a single operation.
authors.affiliation: School of Chemistry, University of Nottingham, University Park, Nottingham, UK NG7 2RD. j.s.clark@nottingham.ac.uk
authors.forename: J Stephen
authors.initials: JS
authors.lastname: Clark
authors.forename: Frédéric
authors.initials: F
authors.lastname: Elustondo
authors.forename: Marc C
authors.initials: MC
authors.lastname: Kimber
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D004987:Ethers / Q000138:chemical synthesis*; D008968:Molecular Conformation; D010084:Oxidation-Reduction
chemical_list: D000480:Alkynes; D004987:Ethers