title: Sedative effects and serum drug concentrations of oxymorphone and metabolites after subcutaneous administration of a liposome-encapsulated formulation in dogs.
authors.affiliation: Department of Surgical Sciences, School of Veterinary, University of Wisconsin, 2015 Linden Drive, Madison, WI 53706, USA. smith@svm.vetmed.wisc.edu
authors.forename: L J
authors.initials: LJ
authors.lastname: Smith
authors.forename: L
authors.initials: L
authors.lastname: Krugner-Higby
authors.forename: L A
authors.initials: LA
authors.lastname: Trepanier
authors.forename: D E
authors.initials: DE
authors.lastname: Flaska
authors.forename: V
authors.initials: V
authors.lastname: Joers
authors.forename: T D
authors.initials: TD
authors.lastname: Heath
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics* / Q000494:pharmacology; D000818:Animals; D004285:Dogs / Q000378:metabolism* / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004337:Drug Carriers / Q000008:administration & dosage; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics* / Q000494:pharmacology; D007279:Injections, Subcutaneous / Q000662:veterinary; D008081:Liposomes / Q000008:administration & dosage; D008297:Male; D010111:Oxymorphone / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics* / Q000494:pharmacology; D012119:Respiration / Q000187:drug effects
chemical_list: D000701:Analgesics, Opioid; D004337:Drug Carriers; D006993:Hypnotics and Sedatives; D008081:Liposomes; D010111:Oxymorphone