title: Isolation, optimization of production and structure-activity relationship studies of monocillin I, the cytotoxic constituent of Paraphaeosphaeria quadriseptata.
authors.affiliation: Southwest Center for Natural Products Research and Commercialization, Office of Arid Lands Studies, College of Agriculture and Life Sciences, University of Arizona, 250 E. Valencia Road, Tucson, Arizona 85706-6800, USA.
authors.forename: E M Kithsiri
authors.initials: EM
authors.lastname: Wijeratne
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Carbonezi
authors.forename: Jacqueline A
authors.initials: JA
authors.lastname: Takahashi
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Seliga
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Turbyville
authors.forename: Elizabeth E
authors.initials: EE
authors.lastname: Pierson
authors.forename: Leland S
authors.initials: LS
authors.lastname: Pierson
authors.forename: Hans D
authors.initials: HD
authors.lastname: VanEtten
authors.forename: Luke
authors.initials: L
authors.lastname: Whitesell
authors.forename: Vanderlan da S
authors.initials: Vda S
authors.lastname: Bolzani
authors.forename: A A Leslie
authors.initials: AA
authors.lastname: Gunatilaka
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification*; D001203:Ascomycota / Q000378:metabolism*; D045744:Cell Line, Tumor; D002851:Chromatography, High Pressure Liquid; D003470:Culture Media; D006801:Humans; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D000903:Antibiotics, Antineoplastic; D003470:Culture Media; D007783:Lactones; C444505:monocillin I