title: Modifications of minimal luminal diameter during the 24 hours following percutaneous treatment of in-stent restenosis.
abstract: The early renarrowing after percutaneous coronary interventions (PCI) for in-stent restenosis (ISR) is a phenomenon that has received little investigation. Therefore, we assessed the angiographic minimal luminal diameter (MLD) before, immediately after, and 24 hours after the procedure in 30 ISR's treated with balloon angioplasty (BA) or rotational atherectomy (RA). The MLD was 0.68+/-0.48 mm at baseline, 2.42+/-0.38 mm after the procedure, and 2.25+/-0.39 mm at 24 hours (p < 0.0001 for all comparisons). Therefore, a small but significant decrease in MLD between post-procedure and 24 hours, corresponding to an early loss of 0.18+/-0.16 mm, was evident. The early loss was not significantly different in ISR's treated with BA or RA (0.15+/-0.16 mm and 0.20+/-0.16 mm, respectively). No significant correlation between early loss and lesion length, diameter stenosis, reference diameter, and acute gain was found. However, no increase of the 24-hour diameter stenosis to more than 50% was observed. We conclude that the magnitude of early luminal loss after PCI of ISR is small and therefore does not generally constitute a clinical problem.
authors.affiliation: Divisione di Cardiologia, Ospedale San Martino, Genoa, Italy. paolo.rubartelli@hsanmartino.it.
authors.forename: Paolo
authors.initials: P
authors.lastname: Rubartelli
authors.forename: Corinna
authors.initials: C
authors.lastname: Giachero
authors.forename: Francesco
authors.initials: F
authors.lastname: Abbadessa
authors.forename: Massimo
authors.initials: M
authors.lastname: Vischi
authors.forename: Sergio
authors.initials: S
authors.lastname: Chierchia
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D017073:Atherectomy / Q000009:adverse effects*; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects; D001837:Body Weights and Measures; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000000981:diagnostic imaging*; D023921:Coronary Stenosis / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015607:Stents / Q000009:adverse effects; D013997:Time Factors