title: Glomus tumor of the duodenum: a case report.
abstract: We describe a rare case of glomus tumor of the duodenum. The tumor was detected in a 46-year-old man being investigated for episodes of gastrointestinal bleeding. The excised specimen showed a 2.3 x 1.5 x 1.5 cm gray-tan tumor involving the mucosa and the submucosa. The overlying mucosa was focally ulcerated. Histologically, the tumor had a solid pattern of sharply demarcated, round glomus cells with prominent pericytoma-like vessels of varying sizes. The neoplastic cells stained for vimentin, smooth muscle actin, and focally for synaptophysin. These histologic and immunohistochemical features are consistent with a diagnosis of glomus tumor of the duodenum.
authors.affiliation: Department of Pathology, Washington Hospital Center, Washington, DC, USA.
authors.forename: Majd
authors.initials: M
authors.lastname: Jundi
authors.forename: Ernest E
authors.initials: EE
authors.lastname: Lack
authors.forename: Erwin A
authors.initials: EA
authors.lastname: Brun
authors.forename: Jesus
authors.initials: J
authors.lastname: Esquivel
authors.forename: Dhruv
authors.initials: D
authors.lastname: Kumar
mesh_terms: D000199:Actins / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D004379:Duodenal Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D005918:Glomus Tumor / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D016708:Synaptophysin / Q000032:analysis; D016896:Treatment Outcome; D014746:Vimentin / Q000032:analysis
chemical_list: D000199:Actins; D014408:Biomarkers, Tumor; D016708:Synaptophysin; D014746:Vimentin