De novo designed peptidic redox potential probe: linking sensitized emission to disulfide bond formation.
The design and utility of a peptidic probe capable of accurately measuring environmental redox potential via sensitized emission has been prepared. This probe is characterized by long-lived luminescence (millisecond), nanomolar detection limits, and a probe reduction potential of -0.243 V.
Lee
Kyung
K
University of Delaware, Department of Chemistry and Biochemistry, Newark, Delaware 19716-2522, USA.
Dzubeck
Valerie
V
Latshaw
Lauren
L
Schneider
Joel P
JP
D004220:Disulfides / Q000138:chemical synthesis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D007700:Kinetics; D009842:Oligopeptides / Q000138:chemical synthesis / Q000737:chemistry*; D010084:Oxidation-Reduction; D017433:Protein Structure, Secondary; D013050:Spectrometry, Fluorescence
D004220:Disulfides; D005456:Fluorescent Dyes; D009842:Oligopeptides