Usefulness of pindolol for treatment of neurocardiogenic syncope.
This study evaluated the efficacy of pindolol, a noncardioselective beta blocker with intrinsic sympathetic activity, on neurocardiogenic syncope using a head-up tilt-table test in 66 patients. Pindolol was equally effective in men and women and the 2 age groups (>60 and <60 years) of the study cohort. The earliest benefit was seen </=3 days after initiating treatment. Side effects were better tolerated in younger patients (age <60 years).
Nair
Nandini
N
Department of Cardiology, Drexel University College of Medicine, Hahnemann University Hospital, Philadelphia, Pennsylvania, USA.
Padder
Farooq A
FA
Kutalek
Steven P
SP
Kantharia
Bharat K
BK
D000293:Adolescent; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000187:drug effects; D004341:Drug Evaluation; D005260:Female; D005500:Follow-Up Studies; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010869:Pindolol / Q000627:therapeutic use*; D019462:Syncope, Vasovagal / Q000188:drug therapy*; D018667:Tilt-Table Test; D016896:Treatment Outcome
D000319:Adrenergic beta-Antagonists; D010869:Pindolol