title: Use of viscodissection and silicone oil in vitrectomy for severe diabetic retinopathy.
abstract: Improvement in surgical techniques has led to improved anatomic and functional success rates following surgery for severe complications of proliferative diabetic retinopathy (PDR). We compared the anatomic and functional outcomes of surgery in a non-randomized, consecutive case series of patients with severe PDR. We found that viscodissection using Healon provides outcomes comparable to conventional pick and scissors dissection. We also found that adjunctive use of silicone oil can salvage selected cases with particularly severe manifestations of PDR (e.g., the fibrinoid syndrome). With proper selection of patients and techniques, the anatomic success rate can exceed 80% even in the most severe cases. The goal of this paper is to show the applicability of using viscodissection and silicone oil infusion during vitrectomy in eyes with severe PDR.
authors.affiliation: Institute of Ophthalmology and Visual Science, New Jersey Medical School, Newark 01701-1709, USA.
authors.forename: R A
authors.initials: RA
authors.lastname: Grigorian
authors.forename: A
authors.initials: A
authors.lastname: Castellarin
authors.forename: N
authors.initials: N
authors.lastname: Bhagat
authors.forename: L
authors.initials: L
authors.lastname: Del Priore
authors.forename: S
authors.initials: S
authors.lastname: Von Hagen
authors.forename: M A
authors.initials: MA
authors.lastname: Zarbin
mesh_terms: D003930:Diabetic Retinopathy / Q000601:surgery*; D004210:Dissection / Q000379:methods*; D006801:Humans; D012827:Silicone Oils / Q000627:therapeutic use*; D014821:Vitrectomy / Q000379:methods*
chemical_list: D012827:Silicone Oils