title: Management of platypnea-orthodeoxia syndrome by transcatheter closure of atrial communication: hemodynamic characteristics, clinical and echocardiographic outcome.
abstract: Percutaneous transcatheter closure of patent foramen ovale or atrial septal defect is an alternative to surgery for the treatment of platypnea-orthodeoxia syndrome. We report the hemodynamic characteristics and clinical and echocardiographic outcomes of 18 patients with platypnea-orthodeoxia syndrome that underwent transcatheter closure of patent foramen ovale or atrial septal defect. Successful closure was achieved in all patients with no in-hospital mortality or adverse events. Complete resolution of symptoms was seen in all patients and mean oxygen saturation increased from 82.6 +/- 5.4% to 96.1+/-2.2% post-procedure (p < 0.01).
authors.affiliation: Massachusetts General Hospital, Boston, MA 02114, USA.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Delgado
authors.forename: Ignacio
authors.initials: I
authors.lastname: Inglessis
authors.forename: Francisco
authors.initials: F
authors.lastname: Martin-Herrero
authors.forename: Danita
authors.initials: D
authors.lastname: Yoerger
authors.forename: Richard
authors.initials: R
authors.lastname: Liberthson
authors.forename: Fernando
authors.initials: F
authors.lastname: Buoanno
authors.forename: Igor
authors.initials: I
authors.lastname: Palacios
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006328:Cardiac Catheterization / Q000379:methods*; D004417:Dyspnea / Q000209:etiology*; D004452:Echocardiography; D004864:Equipment and Supplies; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D006439:Hemodynamics; D006801:Humans; D000860:Hypoxia / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D011187:Posture / Q000502:physiology
chemical_list: D010100:Oxygen