title: A new halopropargylation of alkynes promoted by boron trihalides. highly stereo- and regioselective syntheses of substituted (Z)-1-halo-1,4-enyne derivatives.
abstract: [reaction: see text] A new halopropargylation of alkynes promoted by boron trihalides has been developed. Reactions of (Z)-2-halo-1-vinylboron dihalides (generated in situ via reaction of alkynes with boron trihalides) with lithium propargyloxides in CH(2)Cl(2) at room temperature produce the corresponding (Z)-1-halo-1,4-enynes in modest to good yields.
authors.affiliation: Department of Chemistry, The University of Tennessee, Knoxville, Tennessee 37006-1600, USA. kabalka@utk.edu
authors.forename: George W
authors.initials: GW
authors.lastname: Kabalka
authors.forename: Zhongzhi
authors.initials: Z
authors.lastname: Wu
authors.forename: Yuhong
authors.initials: Y
authors.lastname: Ju