Effectiveness of contact lens disinfectants after lens storage.
OBJECTIVE
To determine the effectiveness of multipurpose contact lens solutions after incubation with lenses for one week.


METHODS
Five multipurpose solutions, three lots each, were preincubated with contact lenses for one week. The solutions were removed and one of three microbes was added to a final concentration of l x l0(6)/mL. The inoculated solutions were incubated for 4 and 6 hours; aliquots were then neutralized, serially diluted, and plated. Plate counts were used to determine the approximate number of organisms that were killed effectively by the contact lens solution.


RESULTS
Of the five solutions tested, only OPTI-FREE Express maintained full effectiveness after preincubation with lenses. The other solutions were effective only with Fusarium solani after the preincubation period.


CONCLUSIONS
We propose that the active component was sufficiently reduced by absorption or inactivation during storage with contact lenses such that it was rendered effective only for F. solani and was no longer concentrated enough to be effective with the bacterial species.
Dannelly
H Kathleen
HK
Department of Life Sciences, Indiana State University, Terre Haute, IN 47809, USA. hdannelly@indstate.edu
Waworuntu
Rosaline V
RV
D001422:Bacterial Adhesion / Q000187:drug effects*; D001431:Bacteriological Techniques; D015169:Colony Count, Microbial; D018639:Contact Lens Solutions / Q000494:pharmacology*; D003261:Contact Lenses / Q000382:microbiology*; D005670:Fusarium / Q000187:drug effects* / Q000254:growth & development; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000254:growth & development; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000254:growth & development
D018639:Contact Lens Solutions