title: [Analysis of disturbances in carbohydrate metabolism in the adult population of Yecla (Murcia, Spain)].
abstract: OBJECTIVE
  To determine the prevalence of impaired fasting glucose (IFG or GBA), impaired glucose tolerance (IGT) and type 2 diabetes mellitus (DM2) in the adult population of Yecla. RESEARCH, DESIGN, AND METHODS: We performed a population-based cross-sectional study (on Primary Care Field) with stratified and random sampling (393) from 17 500 residents in Yecla with sanitary card and aged > or =30 years. We studied 286 subjects (107 declining to participate) and 261 of them (125 men and 136 women) underwent an oral glucose tolerance test (OGTT).
  
  
  METHODS
  World Health Organization (WHO-99) and American Diabetes Association (ADA-97) criteria were used for diagnosis of unknown DM2, GBA and IGT. Socio-demographic and anthropometric variables were measured. Plasma lipid, glycosylated haemoglobin (HbA1C), microalbuminuria and insulin levels also were measured. Insulin resistance was evaluated by the HOMA method.
  
  
  RESULTS
  According ADA-97 criteria the prevalence of DM2 and GBA was 2.65 (CI+/-1.95) and 4.3% (+/-2.5) respectively. Underwent an OGTT, the age-adjusted prevalence of DM2, IGT and GBA (using the Spanish population of July 02) was 6.7 (95%CI, 3,7-9,7); 13.2 (95%CI, 9.1-17.3) and 0.2% (95%CI, 0-1.8) respectively. The known DM2 was 5,9% (95%CI, 3.8-8) and the global prevalence of DM2 was 12.6% (95%CI, 9.6-15.6). The diabetes was associated with overweight, overage and higher insulin, HbA1C and insulin resistance levels.
  
  
  CONCLUSIONS
  There is a high prevalence of DM2 in Yecla (known/unknown 0.87/1). The ADA97 criteria only detected 53% of the unknown DM2. The 78% of normoglycemics subjects had overweight or upper-body fat distribution and diabetics people had higher BMI (Body Mass Index), Hypertension, insulinemia, HbA1C and insulin resistance levels than normoglycemics and IGT subjects.
authors.affiliation: Unidad Docente Medicina Familiar y Comunitaria y Gerencia, Atención Primaria Murcia, Centro Salud Mariano Yago, Yecla, Murcia, Spain. jmartinezc@inicia.es
authors.forename: J
authors.initials: J
authors.lastname: Martínez Candela
authors.forename: A
authors.initials: A
authors.lastname: Gallardo Martín
authors.forename: J
authors.initials: J
authors.lastname: Franch Nadal
authors.forename: J
authors.initials: J
authors.lastname: Romero Ortiz
authors.forename: C
authors.initials: C
authors.lastname: Cánovas Domínguez
authors.forename: R
authors.initials: R
authors.lastname: Gómez Marco
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D050260:Carbohydrate Metabolism; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D018149:Glucose Intolerance / Q000175:diagnosis / Q000453:epidemiology*; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D017678:Sex Distribution; D013030:Spain / Q000453:epidemiology
chemical_list: D001786:Blood Glucose