title: [Guided reconstruction of soft tissue defects of the palate with n-HA/PA66 plates: an experimental study in goats.].
abstract: OBJECTIVE
  To evaluate the effect of n-HA/PA66 plate as a guided implant for the regeneration of the soft tissue defects in palatal region of goats.
  
  
  METHODS
  12 goats were divided into experimental group and control group at random. 18.0 mm x 14.0 mm soft tissue defect and 15.0 mm x 13.0 mm hard tissue defect were formed artificially in hard palate. n-HA/PA66 plates were implanted to the defect in the experimental group. The tissue regeneration in the defects was observed and the structure of regenerating tissue was analyzed by histology.
  
  
  RESULTS
  The mucoperiosteal tissue in the experimental group regenerated along the n-HA/PA66 plates and the mucoperiosteal defects were closed in 6 weeks. The soft and hard tissues were not closed up in control group in 6 weeks.
  
  
  CONCLUSIONS
  n-HA/PA66 plates can guide the regeneration of mucoperiosteal tissue to close the palatal defects.
authors.affiliation: West China College of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: En
authors.initials: E
authors.lastname: Luo
authors.forename: Lan
authors.initials: L
authors.lastname: Yu
authors.forename: Qian
authors.initials: Q
authors.lastname: Zheng
authors.forename: Shi-cheng
authors.initials: SC
authors.lastname: Wei
authors.forename: Han-zhang
authors.initials: HZ
authors.lastname: Wang
authors.forename: Yu-bao
authors.initials: YB
authors.lastname: Li
authors.forename: Jie
authors.initials: J
authors.lastname: Wei
authors.forename: Yi
authors.initials: Y
authors.lastname: Zuo
mesh_terms: D000818:Animals; D006041:Goats; D010159:Palate / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D014945:Wound Healing