[Analysis for epidemic trend of acquired immunodeficiency syndrome in Yunnan Province of China].
OBJECTIVE
To understand epidemiologic characteristics and changes in epidemic trend of human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) in different areas and populations of Yunnan Province.


METHODS
Seroepidemiological studies were conducted in injection drug users (IDUs), women sex workers, whoring goers, patients with sexually transmitted disease (STD), patients with tuberculosis, pregnant women and blood donors with sentinel surveillance, ad hoc investigations, regular case-finding and data collection during 1989 to 2003 in Yunnan Province.


RESULTS
Relatively high prevalence of HIV/AIDS was firstly found in IDUs from border areas of the province in 1989. By December of 2003, totally 14 905 cases with HIV infection were reported in 121 counties of 16 prefectures in Yunnan Province. Prevalence of HIV infection ranged from 21.2% to 27.8% in IDUs, over 40% in IDUs from six areas, and 1.23% to 6.67% and 0.3% to 1.8% in underground prostitutes and whoring goers, respectively. Prevalence of HIV infection was 2.1% to 2.7%, 10.8% in specific areas, in male patients with STD, and was 0.14% to 0.25% in pregnant women during 1993 to 2002 and increased to 0.37% in 2003. Prevalence of HIV infection ranged 1.5% to 1.6% in patients with tuberculosis and 0.01% in blood donors during 1999 to 2000 and increased to 0.07% in 2003.


CONCLUSIONS
Epidemic of HIV infection began in late 1980s in Yunnan, then spread from border areas to inland through IDUs, maintaining a higher prevalence in them to date. Sexual transmission of HIV/AIDS showed an increasing trend in them, with a low prevalence in general population, but appeared a wide spread in local areas.
Lu
Lin
L
The Department of AIDS/STD, Yunnan Provincial Center for Disease Control and Prevention, Kunming 650022, China.
Jia
Man-Hong
MH
Zhang
Xiao-Bo
XB
Luo
Hong-Bing
HB
Ma
Yan-Ling
YL
Fu
Li-Ru
LR
Lu
Ji-Yun
JY
D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology*; D000328:Adult; D002681:China / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000453:epidemiology; D015528:HIV Seroprevalence; D015497:HIV-1; D006801:Humans; D008297:Male; D015995:Prevalence; D012309:Risk-Taking; D018571:Sentinel Surveillance; D012749:Sexually Transmitted Diseases / Q000453:epidemiology; D015819:Substance Abuse, Intravenous / Q000150:complications / Q000453:epidemiology; D011795:Surveys and Questionnaires