Application of lipases in kinetic resolution of racemates.
Lipases have been well established as valuable catalysts in organic synthesis. This review article focuses on some of the recent developments in the rapidly growing field of lipase-catalyzed kinetic resolution of racemates as a versatile method for the separation of enantiomers. The literature search dates back to the last five years and covers some comprehensive examples. The main emphasis is on the use of lipases in organic solvents.
Ghanem
Ashraf
A
Department of Organic Chemistry, University of Geneva, Geneva, Switzerland. ghanem@kfshrc.edu.sa
Aboul-Enein
Hassan Y
HY
D002851:Chromatography, High Pressure Liquid; D003460:Crystallization; D006868:Hydrolysis; D007700:Kinetics; D008049:Lipase / Q000737:chemistry*; D009930:Organic Chemicals / Q000737:chemistry; D012997:Solvents / Q000737:chemistry; D013237:Stereoisomerism
D009930:Organic Chemicals; D012997:Solvents; D008049:Lipase