Bed rest versus free mobilisation following embryo transfer: a prospective randomised study.
OBJECTIVE
To evaluate the efficacy of two clinical methods of post-embryo transfer protocols in patients undergoing in vitro fertilisation.


METHODS
Prospective, randomised clinical trial.


METHODS
Hospital-based clinic for reproductive medicine.


METHODS
Women under 40 years of age who were undergoing in vitro fertilisation with GnRH pituitary down-regulation and controlled ovarian hyperstimulation.


METHODS
Patients were randomised to rest for either 1 or 24 hours after embryo transfer.


METHODS
Clinical pregnancy per cycle rate (the percentage of cycles started that demonstrated a live fetus on ultrasound examination performed at six or seven weeks of gestation).


RESULTS
The clinical pregnancy rates were 21.5% for the 1-hour and 18.2% for the 24-hour post-embryo transfer groups. The implantation rate per embryo was significantly higher in the 1-hour group (14.4%) than in the 24-hour group (9%).


CONCLUSIONS
One-hour and 24-hour rest post-embryo transfer result in comparable rates of clinical pregnancy. However, 24-hour rest results in reduced implantation rate per embryo.
Amarin
Zouhair O
ZO
Department of Obstetrics and Gynaecology, Jordan University of Science and Technology, Irbid, Jordan Fakeeh Hospital, Jeddah, Saudi Arabia.
Obeidat
Basil R
BR
D000328:Adult; D001510:Bed Rest; D004434:Early Ambulation; D004624:Embryo Transfer; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy / Q000706:statistics & numerical data*; D011446:Prospective Studies; D018709:Statistics, Nonparametric