title: Management of massive cerebral infarct.
abstract: Patients with large hemispheric strokes frequently develop neurologic deterioration secondary to cerebral edema. Regardless of the medical and surgical management of cerebral edema, there is high morbidity and mortality. This article reviews the clinical and radiographic features of large hemispheric strokes and examines the various therapeutic options for management of cerebral edema.
authors.affiliation: Neuroscience ICU, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. ghenderson@partners.org
authors.forename: Galen V
authors.initials: GV
authors.lastname: Henderson
mesh_terms: D001921:Brain / Q000473:pathology / Q000503:physiopathology; D001929:Brain Edema / Q000209:etiology; D002544:Cerebral Infarction / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007036:Hypothermia, Induced / Q000379:methods; D019586:Intracranial Hypertension / Q000628:therapy; D007427:Intracranial Pressure / Q000502:physiology; D007511:Ischemia / Q000150:complications / Q000175:diagnosis; D008991:Monitoring, Physiologic; D012306:Risk