Multidrug resistant miliary tuberculosis and Pott's disease in an immunocompetent patient.
In a high tuberculosis TB prevalence country, mortality due to miliary TB is not unknown but the treatment outcome in general is good. We describe a previously healthy man with miliary TB who did not respond to 2-months antituberculous therapy with 4 drugs. Persistent complaints of backache, which antedated chest symptoms, resulted in a diagnosis of Pott's disease. Culture of bronchial aspirate yielded multidrug resistant Mycobacterium tuberculosis that responded slowly to streptomycin, ethionamide, cycloserine, clofazimine, ofloxacin, paraaminosalicylic acid and isoniazid. The association of multidrug resistant miliary TB with Pott's disease in an immunocompetent patient is yet to be highlighted.
Shah
Ashok
A
Department of Respiratory Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India. ashokshah99@yahoo.com
Panjabi
Chandramani
C
Maurya
Vikas
V
Khanna
Puneet
P
D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D018570:Risk Assessment; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014374:Tuberculin Test; D014391:Tuberculosis, Miliary / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D018088:Tuberculosis, Multidrug-Resistant / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D014399:Tuberculosis, Spinal / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy