title: Determination of the free radical scavenging activity of dihydropyran-2,4-diones.
abstract: The antioxidant activities of four synthetic dihydropyran-2,4-diones have been established through the determination of their abilities to inhibit free radicals using DPPH(*) as the stable radical. Whilst all of the compounds exhibited high inhibition percentages, the most active member of the group was 6-phenyl-dihydropyran-2,4-dione. The antioxidant activity of the dihydropyran-2,4-diones is reported here for the first time and extends our knowledge of the range of valuable biological activities associated with this group of compounds.
authors.affiliation: LaSO, Laboratório de Síntese Orgânica, Departamento de Química, CCEN, Universidade Federal de Alagoas, 57.072-970 Maceió, AL, Brazil.
authors.forename: Laura Cristiane
authors.initials: LC
authors.lastname: de Souza
authors.forename: Stella Maris Soares
authors.initials: SM
authors.lastname: de Araújo
authors.forename: Dennis
authors.initials: D
authors.lastname: de Oliveira Imbroisi
mesh_terms: D004095:Dihydropyridines / Q000737:chemistry* / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D016166:Free Radical Scavengers / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D004095:Dihydropyridines; D016166:Free Radical Scavengers