Diagnostic yield of parathyroid hormone testing in children evaluated for hypercalciuria.
Hypercalciuria is a frequent cause of non-glomerular hematuria in pediatric patients. Because hypercalciuria can be secondary to primary hyperparathyroidism, measurement of serum parathyroid hormone (PTH) levels is often performed in children with this urinary abnormality. A retrospective chart review was performed to determine the diagnostic yield of PTH measurements when performed under these clinical circumstances. Over a 30-month period (January 1, 2001 to September 30, 2003), among 31 children who had a PTH determination, the level was elevated in 1 (3%) patient. Based on these findings and the serious nature of untreated primary hyperparathyroidism, serum PTH level should be measured in pediatric patients with newly diagnosed hypercalciuria.
Lo
Christina
C
Department of Pediatrics, Division of Nephrology, Schneider Children's Hospital of the North Shore-Long Island Jewish Health System, New Hyde Park, NY 11040, USA.
Zucker
Yael
Y
Gauthier
Bernard G
BG
Vergara
Marcela
M
Frank
Rachel
R
Vento
Suzanne
S
Trachtman
Howard
H
D002118:Calcium / Q000652:urine*; D002648:Child; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000097:blood* / Q000150:complications; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood*; D012189:Retrospective Studies
D010281:Parathyroid Hormone; D002118:Calcium