Oxidosqualene cyclase second-sphere residues profoundly influence the product profile.
Lodeiro
Silvia
S
Department of Chemistry, Rice University, 6100 S. Main Street, Houston, TX 77005, USA.
Segura
Michael J R
MJ
Stahl
Martin
M
Schulz-Gasch
Tanja
T
Matsuda
Seiichi P T
SP
D002384:Catalysis; D019751:Intramolecular Transferases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D008958:Models, Molecular; D008968:Molecular Conformation; D016296:Mutagenesis; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000235:genetics
D019751:Intramolecular Transferases; C021924:lanosterol synthase; C021923:cycloartenol synthase