title: [Cytomegalovirus infection in peptic ulcer in renal transplant recipient: a case report].
abstract: Gastroduodenal ulcers in renal transplant recipients are usually originated from excessive acid secretion or infection of Helicobacter pyroli. Herein, we report a case of cytomegalovirus (CMV)--induced gastric ulcer following cadaveric renal transplantation. The patient was a 48-year-old man with chronic renal failure and received cadaveric renal transplantation. A month later, he had epigastralgia without CMV-positive antigenemia and received gastrointestinal fiberscopy. Endoscopically, gastric ulcer was identified. Histological findings revealed conspicious nuclear enlargement of the non-epithelial cells in the ulcer bed, which indicated CMV infection. The patient was treated with ganciclovir for 2 weeks and the symptom was relieved. He discharged with a good renal function on day 75 posttransplant. CMV infection plays an important role in gastric ulcer after renal transplantation. Antigenemia assay dose not seem feasible for the detection of CMV-induced gastric ulcer.
authors.affiliation: Department of Urology, Ehime University School of Medicine, Ehime 791-0295, Japan.
authors.forename: Shin
authors.initials: S
authors.lastname: Ishiguro
authors.forename: Tetsuhiro
authors.initials: T
authors.lastname: Ikeda
authors.forename: Kenji
authors.initials: K
authors.lastname: Shimamoto
authors.forename: Nozomu
authors.initials: N
authors.lastname: Tanji
authors.forename: Hiroji
authors.initials: H
authors.lastname: Ohoka
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Yokoyama
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D002102:Cadaver; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000188:drug therapy; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D016867:Immunocompromised Host; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections; D013276:Stomach Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D015774:Ganciclovir