title: Outbreak of hantavirus pulmonary syndrome, Los Santos, Panama, 1999-2000.
abstract: An outbreak of hantavirus pulmonary syndrome occurred in the province of Los Santos, Panama, in late 1999 and early 2000. Eleven cases were identified; 9 were confirmed by serology. Three cases were fatal; however, no confirmed case-patient died. Case-neighborhood serologic surveys resulted in an overall hantavirus antibody prevalence of 13% among household and neighborhood members from the outbreak foci. Epidemiologic investigations did not suggest person-to-person transmission of hantavirus infection. By use of Sin Nombre virus antigen, hantavirus antibodies were detected in Oligoryzomys fulvescens and Zygodontomys brevicauda cherriei. This outbreak resulted in the first documented cases of human hantavirus infections in Central America.
authors.affiliation: Gorgas Memorial Institute for Health Studies, Panama City, Panama.
authors.forename: Vicente
authors.initials: V
authors.lastname: Bayard
authors.forename: Paul T
authors.initials: PT
authors.lastname: Kitsutani
authors.forename: Eduardo O
authors.initials: EO
authors.lastname: Barria
authors.forename: Luis A
authors.initials: LA
authors.lastname: Ruedas
authors.forename: David S
authors.initials: DS
authors.lastname: Tinnin
authors.forename: Carlos
authors.initials: C
authors.lastname: Muñoz
authors.forename: Itza B
authors.initials: IB
authors.lastname: de Mosca
authors.forename: Gladys
authors.initials: G
authors.lastname: Guerrero
authors.forename: Rudick
authors.initials: R
authors.lastname: Kant
authors.forename: Arsenio
authors.initials: A
authors.lastname: Garcia
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Caceres
authors.forename: Fernando G
authors.initials: FG
authors.lastname: Gracio
authors.forename: Evelia
authors.initials: E
authors.lastname: Quiroz
authors.forename: Zoila
authors.initials: Z
authors.lastname: de Castillo
authors.forename: Blas
authors.initials: B
authors.lastname: Armien
authors.forename: Marlo
authors.initials: M
authors.lastname: Libel
authors.forename: James N
authors.initials: JN
authors.lastname: Mills
authors.forename: Ali S
authors.initials: AS
authors.lastname: Khan
authors.forename: Stuart T
authors.initials: ST
authors.lastname: Nichol
authors.forename: Pierre E
authors.initials: PE
authors.lastname: Rollin
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Ksiazek
authors.forename: Clarence J
authors.initials: CJ
authors.lastname: Peters
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D004197:Disease Reservoirs; D005260:Female; D006476:Orthohantavirus / Q000276:immunology; D018804:Hantavirus Pulmonary Syndrome / Q000175:diagnosis / Q000453:epidemiology*; D006306:Health Surveys; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010176:Panama / Q000453:epidemiology; D011159:Population Surveillance; D012377:Rodentia / Q000821:virology
chemical_list: D000914:Antibodies, Viral