Investigation of the origin of C2 units in biosynthesis of streptolydigin.
[reaction: see text] Isotope labeling studies show that malonate, not acetate, furnishes all four C(2) units in the acyltetramic acid streptolydigin. The results are compared with those for pramanicin, and implications for the biosynthetic pathway are discussed.
Chen
Hao
H
Department of Chemistry, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4M1, Canada.
Harrison
Paul H M
PH