title: Treatment of headache with botulinum toxin administration.
abstract: Botulinum toxin has been increasingly applied to the treatment of a wide variety of neurological disorders. Its application to headache disorders, and specifically those classified as migraine or tension-type, followed the observation of its effectiveness in decreasing pain. Studies that have primarily used botulinum toxin type A, but with varying dose regimens and sites of administration, have since observed its beneficial effects and in those subjects, headaches have lessened in their frequency or severity. However, questions that have primarily concerned dose and sites of administration have since arisen and clear guidelines for botulinum toxin use in headache disorders have yet to be developed.
authors.affiliation: Department of Neurology, Loyola University Medical Center, Maywood, IL 60153, USA. ggruene@lumc.edu
authors.forename: Gregory
authors.initials: G
authors.lastname: Gruener
authors.forename: Walter
authors.initials: W
authors.lastname: Jay
mesh_terms: D001905:Botulinum Toxins / Q000627:therapeutic use*; D006261:Headache / Q000188:drug therapy*; D006801:Humans; D008881:Migraine Disorders / Q000188:drug therapy; D018781:Tension-Type Headache / Q000188:drug therapy
chemical_list: D001905:Botulinum Toxins