title: [Study on extraction technology for extract and flavonoids in Chrysanthemum morifolium by orthogonal design].
abstract: OBJECTIVE
  To ascertain extraction technology condition for extract and flavonoids from Chrysanthum morifoliwn.
  
  
  METHODS
  The optimizing ultrasonic extraction condition on the basis of extractive yield and flavonoids were determined by orthogonal design.
  
  
  RESULTS
  The order of factors which affected the flavonoid extraction was extraction times > ethanol concentration > ultrasonic time > solvent quantity.
  
  
  CONCLUSIONS
  The optimum ultrasonic extractions are A2B3C3D3. Compared with traditional extraction, ultraction method is timesaving, simple to operate, stable and need not be heated.
authors.affiliation: College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Yin
authors.forename: Yong-Zhou
authors.initials: YZ
authors.lastname: Hu
authors.forename: Xin-Ji
authors.initials: XJ
authors.lastname: Yang
authors.forename: Xiu-Lan
authors.initials: XL
authors.lastname: Tian
authors.forename: Zhen
authors.initials: Z
authors.lastname: Wang
mesh_terms: D031202:Chrysanthemum / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000032:analysis*; D005419:Flavonoids / Q000032:analysis*; D035264:Flowers / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D004365:Drugs, Chinese Herbal; D005419:Flavonoids