title: Low-grade cervical squamous intraepithelial lesion during pregnancy: conservative antepartum management.
abstract: The purpose of this retrospective study was to determine the regression rate and management of low-grade squamous intraepithelial lesions (LSIL) in pregnancy. Seventy-four women with cytological findings of LSIL were analysed during the pregnant-puerperal period (until 12 months postpartum). Age, parity, cytological and colposcopic findings, route of delivery, and postpartum follow-up were studied. The age and parity of patients ranged (average) from 12 to 32 years (21.2 +/- 4.9), 0-5 (0.89 +/- 1.14), and 9-32 years (16.1 +/- 3.5), respectively. Thirty-nine of 55 (70.9%) and 12 of 19 (63.1%) pregnant women had normal cytology after vaginal delivery and caesarean section, respectively (p > 0.05). In postpartum, eight patients (10.8%) persisted with LSIL and ten (13.5%) presented high-grade squamous intraepithelial lesions. No case of unsatisfactory colposcopy and invasive carcinoma were found. LSIL during pregnancy has a high rate of regression, regardless of the route of delivery. Conservative management with colposcopic evaluation is proposed during gestation.
authors.affiliation: Discipline of Gynaecology and Obstetrics, Faculty of Medicine of Triângulo Mineiro, Uberaba M.G. (Brazil).
authors.forename: E F C
authors.initials: EF
authors.lastname: Murta
authors.forename: F C Goulart
authors.initials: FC
authors.lastname: de Andrade
authors.forename: S J
authors.initials: SJ
authors.lastname: Adad
authors.forename: Hazarabedian
authors.initials: H
authors.lastname: de Souza
mesh_terms: D000293:Adolescent; D000328:Adult; D001938:Brazil / Q000453:epidemiology; D002648:Child; D003127:Colposcopy; D005260:Female; D006801:Humans; D008499:Medical Records; D049590:Postpartum Period; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D011295:Prenatal Care; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D014626:Vaginal Smears; D002578:Uterine Cervical Dysplasia / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*