title: [Sentinel node study with patent blue in cervical cancer].
abstract: OBJECTIVE
  The purpose of this study was to determine the feasibility of sentinel node identification in patients with invasive cervix cancer undergoing radical hysterectomy and pelvic lymphadenectomy using intraoperative lymphatic mapping with patent blue dye.
  
  
  METHODS
  Fifty one patients wtih Figo I and II cervical cancer were submitted to radical hysterectomy and pelvic lymphadenectomy. The patent blue V was injected around the tumor before beginning surgery. At the time of pelvic lymphadenectomy, lymph nodes with obvious uptake of the dye were separated from the remainder of the lymphadenectomy specimen.
  
  
  RESULTS
  Sentinel nodes were detected in 32 of the 51 patients. Four cases of false negative were observed. The specificity, sensitivity, positive predictive value and negative predictive value were 38.6%, 42.8%, 10% and 80.9%, respectively.
  
  
  CONCLUSIONS
  Identification of sentinel node with patent blue dye is feasible in cervical cancer. A larger series will be required to establish sentinel detection in cervical cancer for further therapy concepts and planning.
authors.affiliation: Departamento de Clínica Geral, Universidade Federal do Piauí e Hospital São Marcos, Teresina, PI. sabasmarcia@uol.com.br
authors.forename: Sabas Carlos
authors.initials: SC
authors.lastname: Vieira
authors.forename: Luiz Carlos
authors.initials: LC
authors.lastname: Zeferino
authors.forename: Benedito Borges da
authors.initials: BB
authors.lastname: Silva
authors.forename: Jerúsia O Ibiapina de
authors.initials: JO
authors.lastname: Santana
authors.forename: Lina Gomes dos
authors.initials: LG
authors.lastname: Santos
authors.forename: Teresinha Castello Branco
authors.initials: TC
authors.lastname: Carvalho
authors.forename: Maria Castelo Branco de Deus
authors.initials: MC
authors.lastname: Rocha
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000556:secondary; D004396:Coloring Agents; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology* / Q000601:surgery; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009367:Neoplasm Staging; D010388:Pelvis; D012394:Rosaniline Dyes; D012680:Sensitivity and Specificity; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis*
chemical_list: D004396:Coloring Agents; D012394:Rosaniline Dyes; C008769:sulfan blue