title: Hemi-spinal cord infarction due to vertebral artery dissection in congenital afibrinogenemia.
abstract: Isolated ischemia of the cervical spinal cord is an uncommon but increasingly recognized complication of vertebral artery dissection (VAD). The authors report a young patient with congenital afibrinogenemia, who developed VAD with extensive unilateral spinal cord infarction, probably caused by local compression of spinal radicular feeders at their origin by vertebral artery hematoma.
authors.affiliation: Department of Neurology, J.W. Goethe-University, Frankfurt am Main, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Laufs
authors.forename: S
authors.initials: S
authors.lastname: Weidauer
authors.forename: C
authors.initials: C
authors.lastname: Heller
authors.forename: M
authors.initials: M
authors.lastname: Lorenz
authors.forename: T
authors.initials: T
authors.lastname: Neumann-Haefelin
mesh_terms: D000328:Adult; D000347:Afibrinogenemia / Q000150:complications* / Q000151:congenital; D000925:Anticoagulants / Q000627:therapeutic use; D002574:Cervical Vertebrae; D005260:Female; D005340:Fibrinogen / Q000627:therapeutic use; D006732:Horner Syndrome / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D010291:Paresis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D013116:Spinal Cord / Q000098:blood supply / Q000473:pathology* / Q000503:physiopathology; D020760:Spinal Cord Ischemia / Q000209:etiology* / Q000473:pathology* / Q000503:physiopathology; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex; D014711:Vertebral Artery / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D020217:Vertebral Artery Dissection / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*
chemical_list: D000925:Anticoagulants; D005340:Fibrinogen