title: Salmonellosis and ulcerative colitis. A causal relationship or just a coincidence.
abstract: Coincidence of salmonellosis and ulcerative colitis is a rare clinical problem. Salmonella infection was reported to complicate the ulcerative colitis, as either facilitating its occurrence or activation. In this article, we present a case with salmonellosis whose clinicopathological findings also suggested ulcerative colitis. The patient improved rapidly after taking additional mesalazine to norfloxacin treatment. We conclude that salmonella infection might have either been coincidentally present or might have triggered an early ulcerative colitis in this patient who did not have history of inflammatory bowel diseases. In case of persistent severe diarrhea despite appropriate treatment, the possibility of a coincident inflammatory bowel disease such as ulcerative colitis should always be considered, especially in endemic regions for salmonellosis.
authors.affiliation: Department of Gastroenterology, School of Medicine, Adnan Menderes University, Aydin, Turkey. karaogluaok@yahoo.com
authors.forename: Ali O
authors.initials: AO
authors.lastname: Karaoglu
authors.forename: Vahit
authors.initials: V
authors.lastname: Yukselen
authors.forename: Gunay T
authors.initials: GT
authors.lastname: Ertem
authors.forename: Muhan
authors.initials: M
authors.lastname: Erkus
mesh_terms: D000006:Abdomen, Acute / Q000175:diagnosis / Q000209:etiology; D000328:Adult; D001707:Biopsy, Needle; D003093:Colitis, Ulcerative / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D003113:Colonoscopy; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007413:Intestinal Mucosa / Q000473:pathology; D008297:Male; D019804:Mesalamine / Q000627:therapeutic use; D009643:Norfloxacin / Q000627:therapeutic use; D018570:Risk Assessment; D012480:Salmonella Infections / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D012477:Salmonella enteritidis / Q000302:isolation & purification*; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D019804:Mesalamine; D009643:Norfloxacin