An unusual presentation of primary amyloidosis.
A 65-year-old male patient presented with right upper-quadrant abdominal pain. Ultrasonography revealed hypoechoic lesion in the perihepatic and intraparenchymal area. Computed tomography (CT) showed hypodense lesion in the same localization. A fine needle biopsy specimen of the perihepatic lesion was hemorrhagic. On abdominal CT, the liver showed enhancement, but the spleen did not enhance. The spleen could not be detected by scintigraphic imaging using Tc99m sulfur dioxide. A diagnosis of primary amyloidosis was made by renal biopsy. Melphalan 10 mg/day for 4 days/month was started. The clinical and radiological follow up demonstrated a resorption of the hematoma. The patient is still alive at the eighth month of therapy.
Dursun
Mehmet
M
Department of Gastroenterology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey. dursunm@dicle.edu.tr
Ayyildiz
Orhan
O
Yilmaz
Serif
S
Bilici
Aslan
A
D015746:Abdominal Pain / Q000175:diagnosis* / Q000209:etiology; D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis* / Q000188:drug therapy; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006406:Hematoma / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007150:Immunohistochemistry; D008107:Liver Diseases / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008558:Melphalan / Q000627:therapeutic use; D011877:Radionuclide Imaging; D018570:Risk Assessment; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018608:Ultrasonography, Doppler
D008558:Melphalan