title: [A clinical study of estramustine phosphate sodium for the treatment of hot flushes in men with prostate cancer].
abstract: OBJECTIVE
  To assess the effectiveness and tolerability of estramustine sodium phosphate in men with hot flushes during combined androgen blockade (CAB) therapy for prostate cancer.
  
  
  METHODS
  Seven men with moderate to severe hot flushes were received estramustine sodium phosphate. Treatment response was assessed by hot flush score.
  
  
  RESULTS
  A significant reduction in the hot flush score was seen with all patients. No thromboembolic complications occurred in any patients.
  
  
  CONCLUSIONS
  Estramustine sodium phosphate appears to be a promising, well-tolerated and useful therapy for men with hot flushes during CAB treatment for prostate cancer.
authors.affiliation: Department of Urology, Ikeda Municipal Hospital.
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Fukuhara
authors.forename: Shohei
authors.initials: S
authors.lastname: Yokoyama
authors.forename: Koichi
authors.initials: K
authors.lastname: Tsutahara
authors.forename: Naoki
authors.initials: N
authors.lastname: Mori
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Hara
authors.forename: Seiji
authors.initials: S
authors.lastname: Yamaguchi
mesh_terms: D000368:Aged; D000726:Androgen Antagonists / Q000009:adverse effects*; D004961:Estramustine / Q000627:therapeutic use*; D019584:Hot Flashes / Q000139:chemically induced* / Q000188:drug therapy*; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000726:Androgen Antagonists; D004961:Estramustine