Langerhans cell histiocytosis: report of a single organ involvement in a child.
Langerhans cell histiocytosis is a rare disorder characterized by abnormal proliferation of Langerhans cells that can affect various organ systems. The disease usually presents as a unifocal lytic bone lesion and can affect any age group. Less frequently it presents as a disseminated disease with multisystem involvement. Hepatic manifestation in Langerhans cell histiocytosis is relatively rare and usually presents as a part of a disseminated process. We report a case of Langerhans cell histiocytosis involving only the liver in a 9-years-old child.
Buza
Natalia
N
Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, New Orleans, LA 70112-2699, USA.
Lagarde
D C
DC
Dash
Srikanta
S
Haque
Salima
S
D001707:Biopsy, Needle; D002648:Child; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008099:Liver / Q000473:pathology*; D008103:Liver Cirrhosis / Q000473:pathology