[The isolation and identification of two new epimer from the mother liquid of testosterone].
OBJECTIVE
To study the impurity of the drug testosterone.


METHODS
Chromatography methods were used to separate the chemical constituents. Their structures were determined by NMR and MS spectral analysis.


RESULTS
Two new epimers were isolated from the mother liquid of the drug.


CONCLUSIONS
These new epimers were identified as 3alpha-ethoxyandrost-4-en-17beta-ol, 3beta-ethoxyandrost-4-en-17beta-ol.
Yang
Zhong-Duo
ZD
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Wang
You-Fu
YF
Lin
Li-Bo
LB
Li
Yuan-Chao
YC
D000737:Androstenols / Q000737:chemistry / Q000302:isolation & purification*; D004340:Drug Contamination; D008968:Molecular Conformation; D015394:Molecular Structure; D013237:Stereoisomerism; D013739:Testosterone / Q000737:chemistry*
C494585:3-ethoxyandrost-4-en-17-ol; D000737:Androstenols; D013739:Testosterone