cis-Eudesmane sesquiterpene glycosides from Liriope muscari and Ophiopogon japonicus.
Two new cis-eudesmane sesquiterpene glycosides, liriopeoside A (1) and ophiopogonoside A (2), were extracted and purified from tubers of Liriope muscari and Ophiopogon japonicus, respectively, along with three known compounds. Their structures were elucidated as 1beta,6beta-dihydroxy-cis-eudesm-3-ene-6-O-beta-D-glucopyranoside (1) and 1beta,4beta,6beta-trihydroxy-cis-eudesmane-6-O-beta-D-glucopyranoside (2) by spectral data analysis. The structure and the relative configuration of compound 1 were confirmed by X-ray crystallographic analysis. This is the first time that cis-eudesmane-type sesquiterpenes have been reported from the genera Ophiopogon and Liriope.
Cheng
Zhi-Hong
ZH
Department of Complex Prescription of Chinese Materia Medica, China Pharmaceutical University, Nanjing 210009, Jiangsu, People's Republic of China.
Wu
Tao
T
Bligh
S W Annie
SW
Bashall
Alan
A
Yu
Bo-Yang
BY
D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D031424:Liriope Plant / Q000737:chemistry*; D008516:Medicine, Chinese Traditional; D008968:Molecular Conformation; D015394:Molecular Structure; D031441:Ophiopogon / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D045787:Sesquiterpenes, Eudesmane / Q000737:chemistry / Q000302:isolation & purification*
D006027:Glycosides; D045787:Sesquiterpenes, Eudesmane; C493744:liriopeoside A; C493745:ophiopogonoside A