title: Role of multisection CT angiography in the evaluation of vertebrobasilar vasospasm in patients with subarachnoid hemorrhage.
abstract: OBJECTIVE
  Optimal means for assessing cerebral vasospasm, mainly at the vertebrobasilar system, have not been established. The purpose of this study was to evaluate the role of multisection CT angiography (MCTA) in the detection and quantification of vertebrobasilar vasospasm (VBS) indicated on transcranial Doppler (TCD) imaging in patients with subarachnoid hemorrhage (SAH).
  
  
  METHODS
  Forty-three MCTA studies of the vertebrobasilar arteries were performed with a multisection spiral CT scanner in 36 patients with SAH. Parameters used were 1-mm collimation, 0.625Q pitch, 120 kV, and 250 mAs. Contrast material was injected (80-100 mL, 3 mL/s) after a 15-20-second delay. Postprocessing of the vertebrobasilar system was performed by using maximum intensity projection and volume-rendering reconstruction. Vessel diameter was measured at different intracranial locations along the vertebral and basilar arteries perpendicular to their long axis by using curved reformatted multiplanar reformation. TCD imaging of the posterior circulation was performed within 24 hours.
  
  
  RESULTS
  MCTA demonstrated narrowed arteries compatible with VBS in 13 patients, consistent with TCD findings. Despite TCD recordings of high flow velocity in three other patients, MCTA did not reveal vasospasm but did show wide arteries feeding arteriovenous malformations in two and normal-sized arteries in one. VBS in two patients was identified on MCTA but overlooked during TCD imaging. Twenty patients had normal findings on both TCD and MCTA studies.
  
  
  CONCLUSIONS
  Cerebral MCTA is recommended as a reliable, rapid, and minimally invasive diagnostic method, one complementary to TCD imaging for assessing VBS in patients with SAH.
authors.affiliation: Department of Radiology, Rambam Medical Center, Haifa, Israel.
authors.forename: Dorith
authors.initials: D
authors.lastname: Goldsher
authors.forename: Reuven
authors.initials: R
authors.lastname: Shreiber
authors.forename: Venyamin
authors.initials: V
authors.lastname: Shik
authors.forename: Yonit
authors.initials: Y
authors.lastname: Tavor
authors.forename: Jean F
authors.initials: JF
authors.lastname: Soustiel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001488:Basilar Artery / Q000000981:diagnostic imaging; D001783:Blood Flow Velocity; D002533:Cerebral Angiography; D020202:Cerebral Hemorrhage, Traumatic / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D002538:Intracranial Arteriovenous Malformations / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D012016:Reference Values; D012680:Sensitivity and Specificity; D013223:Statistics as Topic; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging*; D036542:Tomography, Spiral Computed; D017585:Ultrasonography, Doppler, Transcranial; D020301:Vasospasm, Intracranial / Q000000981:diagnostic imaging*; D014711:Vertebral Artery / Q000000981:diagnostic imaging; D014715:Vertebrobasilar Insufficiency / Q000000981:diagnostic imaging*