HIV-host interactions: vital to the virus and key to its inhibition.
Much progress has been made in recent years in the investigation of the interplay between HIV-1 and its host cells. Most of these interactions are complex and have not yet been fully unraveled. Nevertheless, current knowledge on the molecular interactions between HIV and host-cell factors has substantially broadened our understanding of the viral life cycle and opened new investigative areas for drug intervention.
Trkola
Alexandra
A
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, 8091 Zurich, Switzerland. alexandra.trkola@usz.ch
D002478:Cells, Cultured; D015967:Gene Expression Regulation, Viral; D015497:HIV-1 / Q000235:genetics / Q000472:pathogenicity* / Q000502:physiology; D006801:Humans; D011506:Proteins / Q000378:metabolism*; D012191:Retroviridae Proteins / Q000378:metabolism*; D014779:Virus Replication
D011506:Proteins; D012191:Retroviridae Proteins