The influence of obstructive sleep apnea on FFR measurements for coronary lesion assessment.
Fractional flow reserve (FFR) determinations have been demonstrated to be largely independent of changes in systemic hemodynamic changes. Herein, we describe a case of obstructive sleep apnea cyclically altering FFR measurements from normal to abnormal in a patient with an intermediately severe coronary narrowing following treatment for an acute coronary syndrome. To eliminate uncertainty, FFR measurements should be made if possible during suspended respiration.
Ciaramita
Jeffrey P
JP
J. Gerard Mudd Cardiac Catheterization Laboratory, St. Louis University Health Sciences Center, 3635 Vista Avenue at Grand Boulevard, St. Louis, MO 63110, USA.
Parham
Walter A
WA
Herrmann
Steven
S
Khoukaz
Souheil
S
Kern
Morton J
MJ
D001783:Blood Flow Velocity; D001794:Blood Pressure / Q000502:physiology; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000502:physiology*; D003327:Coronary Disease / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D003331:Coronary Vessels / Q000502:physiology*; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000502:physiology; D008875:Middle Aged; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000503:physiopathology*; D014655:Vascular Resistance / Q000502:physiology