[Role of human and bacterial heat shock proteins in inflammatory and immunological mechanisms of atherosclerosis].
Atherosclerosis remains the leading cause of morbidity and mortality in many countries. Recent studies have demonstrated that the pathogenesis of atherosclerosis involves not only lipid deposition, but also the inflammatory process. The heat shock proteins (HSPS) are expressed in normal cells but their expression is enhanced by a number of different stress factors including heat and ischaemia. They play important roles in chaperoning the "folding" of other proteins and in protein degradation.
Rajtar
Renata
R
II Klinika Kardiologii Instytutu Kardiologii, Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.
Kloch
Małgorzata
M
Kolasińska-Kloch
Władysława
W
D000818:Animals; D001161:Arteriosclerosis / Q000276:immunology / Q000378:metabolism* / Q000503:physiopathology; D006360:Heat-Shock Proteins / Q000276:immunology / Q000378:metabolism*; D006801:Humans; D017202:Myocardial Ischemia / Q000276:immunology / Q000378:metabolism* / Q000503:physiopathology
D006360:Heat-Shock Proteins