title: Utilization of macrophages in anticancer therapy: the macrophage network theory.
abstract: Appropriate and rational modulation of innate immunity may enhance the therapeutic efficacy of emerging immune therapies for treating cancer. One of the crucial cells of innate immunity is the macrophage. The purpose of this article was to review those issues that suggest ways of exploiting macrophage local functions in immune therapy, and to discuss the suitability of low molecular-weight lipopolysaccharides as potent modulators of macrophage functions for immune therapy of cancer.
authors.affiliation: Institute for Health Science, Tokushima Bunri University, Nishihama, Yamashiro-cho, Tokushima-shi, Japan.
authors.forename: Chie
authors.initials: C
authors.lastname: Kohchi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Inagawa
authors.forename: Mami
authors.initials: M
authors.lastname: Hino
authors.forename: Mutsumi
authors.initials: M
authors.lastname: Oda
authors.forename: Kazue
authors.initials: K
authors.lastname: Nakata
authors.forename: Aya
authors.initials: A
authors.lastname: Yoshida
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Hori
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Terada
authors.forename: Kimiko
authors.initials: K
authors.lastname: Makino
authors.forename: Kunio
authors.initials: K
authors.lastname: Takiguchi
authors.forename: Gen-Ichiro
authors.initials: G
authors.lastname: Soma
mesh_terms: D000818:Animals; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D008070:Lipopolysaccharides / Q000276:immunology / Q000494:pharmacology*; D008262:Macrophage Activation / Q000187:drug effects / Q000276:immunology; D008264:Macrophages / Q000187:drug effects / Q000276:immunology*; D009369:Neoplasms / Q000276:immunology* / Q000628:therapy*
chemical_list: D008070:Lipopolysaccharides