[Detection of free testosterone in the serum and semen of idiopathic oligospermia patients and its significance].
OBJECTIVE
To detect free testosterone (FT) in the serum and semen of patients with idiopathic oligospermia, and further analyze the relationship between FT and idiopathic oligospermia.


METHODS
Blood samples were collected from the males of a normal control group (n = 44) and an idiopathic oligospermia group (n = 44) at 8:00-10:00 a.m.. Semen samples were collected from the males of a normal control group (n = 30) and an idiopathic oligospermia group (n = 37) at the same time. Sperm density was detected by routine semen analysis, and FT in the serum and semen was detected by RIA.


RESULTS
There was no significant difference in the serum concentrations of FT between the groups of normal control [(97.50 +/- 46.96) pmol/L] and idiopathic oligospermia [(94.88 +/- 42.04) pmol/L], P > 0.5. But the difference was significant in the semen concentrations of FT between the groups of normal control [(2.01 +/- 0.32) pmol/L] and idiopathic oligospermia [(0.52 +/- 0.44) pmol/L], P < 0.01.


CONCLUSIONS
Measurement of semen FT concentration could early reflect the function of the testis, which contributes to the early diagnosis and treatment of idiopathic oligospermia.
Wang
Guohong
G
Laboratory of Radioimmunoassay, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.
Xu
Ruiji
R
Zhang
Zhongshu
Z
Wang
Xiaojie
X
D000328:Adult; D016022:Case-Control Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009845:Oligospermia / Q000097:blood / Q000378:metabolism*; D012661:Semen / Q000737:chemistry*; D013739:Testosterone / Q000097:blood / Q000378:metabolism*
D013739:Testosterone