title: ACOG practice bulletin: Clinical management guidelines for obstetrician-gynecologists, number 57, November 2004. Gynecologic herpes simplex virus infections.
abstract: Both herpes simplex virus (HSV) type I and HSV type 2 can cause genital herpes. Because the infection is chronic, genital herpes has become the most common sexually transmitted disease among women. The prevalence of the HSV-2 antibody among women in the United States is 26%, although genital herpes has been diagnosed in only a small proportion (10-25%) of individuals with HSV-2 antibodies. Herpes simplex virus type I is becoming a more frequent cause of genital herpes, especially among young women. Overall,HSV-I seroprevalence in the United States is estimated at 67%, although sero-logic data do not provide information about site of infection. Recent advances in diagnostic methods and therapeutic options are likely to change the management of genital herpes.
mesh_terms: D015075:2-Aminopurine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000212:Acyclovir / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D000077595:Famciclovir; D005260:Female; D006558:Herpes Genitalis / Q000175:diagnosis* / Q000188:drug therapy* / Q000821:virology; D018259:Herpesvirus 1, Human / Q000502:physiology; D018258:Herpesvirus 2, Human / Q000502:physiology; D006801:Humans; D000077483:Valacyclovir; D014633:Valine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014775:Virus Activation
chemical_list: D000998:Antiviral Agents; D015075:2-Aminopurine; D014633:Valine; D000077483:Valacyclovir; D000077595:Famciclovir; D000212:Acyclovir