title: Lack of response to isotretinoin in annular elastolytic giant cell granuloma.
abstract: Annular elastolytic giant cell granuloma is a rare disease characterized by annular configurated lesions with typical histopathologic findings. We report a case of annular elastolytic giant cell granuloma in a 50-year-old male patient. Treatment modalities for this disease are limited and mostly unsatisfactory, although isotretinoin was found to be effective in a single case. However, systemic isotretinoin treatment of 12 weeks' duration was of no benefit in the presented case.
authors.affiliation: Süleyman Demirel University Faculty of Medicine Department of Dermatology, Isparta, Turkey.
authors.forename: Pinar Y
authors.initials: PY
authors.lastname: Basak
authors.forename: Ilkay
authors.initials: I
authors.lastname: Icke
authors.forename: Vahide B
authors.initials: VB
authors.lastname: Akkaya
authors.forename: Kayhan
authors.initials: K
authors.lastname: Basak
mesh_terms: D000284:Administration, Oral; D003937:Diagnosis, Differential; D006101:Granuloma, Giant Cell / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage / Q000627:therapeutic use*; D007641:Keratolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009333:Neck; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D017211:Treatment Failure
chemical_list: D007641:Keratolytic Agents; D015474:Isotretinoin