Best evidence topic report. Non-steroidal anti-inflammatory drugs and exacerbations of asthma in children.
A short cut review was carried out to establish whether non-steroidal anti-inflammatory agents cause exacerbations of asthma in children. Altogether 301 papers were found using the reported search, of which two presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these best papers are tabulated. A clinical bottom line is stated.
Body
Richard
R
Department of Emergency Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.
Potier
Katherine
K
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D001249:Asthma / Q000139:chemically induced*; D002648:Child; D004630:Emergencies; D005334:Fever / Q000188:drug therapy*; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects*; D008297:Male
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007052:Ibuprofen