[Pancreatic tumor revealed by metastatic bilateral ovarian tumor with virilisation syndrome].
We report a case of a 38-year-old patient presenting with both pancreatic and a bilateral ovarian tumor revealed by a virilization syndrome. Clinically, both tumors were conceivably distinct. However, on histological examination, they were found to be morphologically similar, with neuroendocrine features, suggesting that pancreatic tumor was a primitive neoplasm and the ovarian one a metastatic spread of that lesion. The virilization syndrome was due to the functional status of the ovarian tumors that was confirmed by immunohistochemical detection of inhibin.
Baranzelli
M-C
MC
Département des laboratoires, centre Oscar-Lambret, 3, rue Frédéric-Combemale, BP 307, 59020 Lille, France. mc-baranzelli@o-lambret.fr
Chauvet
M-P
MP
Vanseymortier
L
L
Cabaret
V
V
D000328:Adult; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D018358:Neuroendocrine Tumors / Q000378:metabolism* / Q000473:pathology / Q000556:secondary; D010051:Ovarian Neoplasms / Q000473:pathology / Q000556:secondary*; D010190:Pancreatic Neoplasms / Q000473:pathology*; D013577:Syndrome; D014770:Virilism / Q000209:etiology