title: Testicular granulocytic sarcoma, a source of diagnostic confusion.
abstract: We report a case of granulocytic sarcoma of the testis without hematologic manifestations. The patient was disease free 7 years after the initial presentation. The initial pathology interpretation favored a diagnosis of high-grade non-Hodgkin's lymphoma but additional histologic staining confirmed the diagnosis of granulocytic sarcoma. Only 2 cases of testicular granulocytic sarcoma without an associated hematologic disorder have been described. To our knowledge, this is the third reported case. The diagnosis of this rare tumor is difficult and should be in the differential diagnosis when non-Hodgkin's lymphoma is considered.
authors.affiliation: Department of Urological Surgery, Lister Hospital, Stevenage, Herts, United Kingdom.
authors.forename: J
authors.initials: J
authors.lastname: Constantinou
authors.forename: T
authors.initials: T
authors.lastname: Nitkunan
authors.forename: M
authors.initials: M
authors.lastname: Al-Izzi
authors.forename: T A
authors.initials: TA
authors.lastname: McNicholas
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D002467:Cell Nucleus / Q000648:ultrastructure; D003520:Cyclophosphamide / Q000008:administration & dosage; D003561:Cytarabine / Q000008:administration & dosage; D003594:Cytoplasmic Granules / Q000737:chemistry / Q000648:ultrastructure; D003630:Daunorubicin / Q000008:administration & dosage; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D011239:Prednisolone / Q000008:administration & dosage; D023981:Sarcoma, Myeloid / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014408:Biomarkers, Tumor; D003561:Cytarabine; D014750:Vincristine; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone; D008727:Methotrexate; D003630:Daunorubicin