title: New sesterterpenes from the sponge Smenospongia sp.
abstract: Five new sesterterpenes, three scalarane-type (1-3) and two linear furanosesterterpenes (4, 5), were isolated from the marine sponge Smenospongia sp. collected from Gagu-Do, Korea. The structures of the new compounds, which exhibited moderate cytotoxicity toward the human leukemia cell line K562, were determined from an analysis of spectroscopic data.
authors.affiliation: Marine Natural Products Laboratory, Korea Ocean Research & Development Institute, Ansan PO Box 29, Seoul 425-600.
authors.forename: Jung-Rae
authors.initials: JR
authors.lastname: Rho
authors.forename: Hyi-Seung
authors.initials: HS
authors.lastname: Lee
authors.forename: Hee Jae
authors.initials: HJ
authors.lastname: Shin
authors.forename: Jong-Woong
authors.initials: JW
authors.lastname: Ahn
authors.forename: Ji-Yun
authors.initials: JY
authors.lastname: Kim
authors.forename: Chung J
authors.initials: CJ
authors.lastname: Sim
authors.forename: Jongheon
authors.initials: J
authors.lastname: Shin
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D020014:K562 Cells; D007723:Korea; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry*; D054830:Sesterterpenes; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D054830:Sesterterpenes; D013729:Terpenes