In vivo dynamics of an immune response in the bumble bee Bombus terrestris.
Concepts from evolutionary ecology have recently been applied to questions of immune defences. However, an important but often neglected aspect is the temporal dynamics of the simple immune measures used in ecological studies. Here, we present observations for workers of the bumble bee Bombus terrestris on the dynamics of the phenoloxidase (PO) system, antibacterial activity, and the total number of haemocytes following a challenge with immune elicitors (LPS, Laminarin), over a time-span ranging from 1min to 14 days. The dynamics of the PO measurement showed a complex pattern and was correlated with haemocyte counts. Antibacterial activity, on the other hand, increased sharply between 2 and 24h post-challenge followed by a slow decrease. Surprisingly, the effects of a challenge lasted up to 14 days.
Korner
P
P
Ecology and Evolution, ETH-Zentrum NW, 8092 Zurich, Switzerland. pius.korner@bluewin.ch
Schmid-Hempel
P
P
D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000818:Animals; D001516:Bees / Q000276:immunology*; D005260:Female; D005936:Glucans; D006434:Hemocytes / Q000166:cytology / Q000187:drug effects; D006458:Hemolymph / Q000276:immunology; D008070:Lipopolysaccharides / Q000494:pharmacology; D008297:Male; D014442:Monophenol Monooxygenase / Q000187:drug effects / Q000378:metabolism; D011134:Polysaccharides / Q000494:pharmacology; D013997:Time Factors
D000276:Adjuvants, Immunologic; D005936:Glucans; D008070:Lipopolysaccharides; D011134:Polysaccharides; C008247:laminaran; D014442:Monophenol Monooxygenase