ALSFRS-R.
The ALSFRS-R is an attractive primary outcome measure in clinical trials of ALS because it is validated, easy to administer, minimizes dropout, reduces cost, and correlates with survival. Unlike the other standard outcome measures currently employed, the ALSFRS-R is also a measure of global function.
Gordon
Paul H
PH
Eleanor and Lou Gehrig MDA/ALS Research Center, Neurological Institute, New York, NY 10032, USA. pgordon@neuro.columbia.edu
Miller
Robert G
RG
Moore
Dan H
DH
D000203:Activities of Daily Living; D000690:Amyotrophic Lateral Sclerosis / Q000188:drug therapy / Q000523:psychology*; D002986:Clinical Trials as Topic; D006801:Humans; D017063:Outcome Assessment, Health Care / Q000379:methods*; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D018434:Sickness Impact Profile