title: Effect of contraceptives on the prevalence of vaginal colonization with Candida species in Edo State, Nigeria.
abstract: High vaginal swabs (HVS) obtained from 500 volunteers in Edo State, Nigeria which comprised 394 contraceptive users and 106 non-contraceptive users were screened for the prevalence of Candida species using standard procedures. Results revealed the isolation of Candida species in 246 of volunteers. These included Candida albicans 174 (38.4%), Candida pseudotropicalis 20 (4%), Candida stellatoidea 15 (3%), Candida krusei nine (1.8%), Candida guilliermondii 12 (2.4%), Candida tropicalis 11 (2.2%) and Candida glabrata five (1%). Of the 394 contraceptive users, 203 (51.5%) had Candida species isolated from them compared to 43 (40.6%) from 106 non-contraceptive users. There was significant relationship (P<0.001) between the type of contraceptive used and the prevalence of vaginal colonization. Age and marital status of the volunteers sampled had significant relationship (P<0.001) with the prevalence of vaginal colonization. Results have revealed an association between use of contraceptive and the prevalence of vaginal colonization in our environment.
authors.affiliation: Department of Microbiology, Faculty of Natural Sciences, Ambrose Alli University, P.M.B. 14, Ekpoma, Edo State, Nigeria. ibenweani@hotmail.com
authors.forename: I B
authors.initials: IB
authors.lastname: Enweani
authors.forename: H C
authors.initials: HC
authors.lastname: Gugnani
authors.forename: R
authors.initials: R
authors.lastname: Okobia
authors.forename: S B
authors.initials: SB
authors.lastname: Ojo