title: A rare case of de novo distal 19q trisomy prenatally diagnosed.
abstract: We present a case of de novo trisomy of distal 19q diagnosed prenatally by cytogenetics and FISH analysis. The autopsy performed after termination of the pregnancy showed major internal and external malformations that are associated with this chromosome abnormality.
authors.affiliation: Institut de Pathologie et de Génétique, Loverval, Belgium. sonia.rombouts@ipg.be
authors.forename: Sonia
authors.initials: S
authors.lastname: Rombout
authors.forename: Daniel
authors.initials: D
authors.lastname: Sartenaer
authors.forename: Benoît
authors.initials: B
authors.lastname: Parmentier
authors.forename: Christian
authors.initials: C
authors.lastname: Dugauquier
authors.forename: Yves
authors.initials: Y
authors.lastname: Gillerot
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics* / Q000473:pathology; D000328:Adult; D000649:Amniocentesis; D000653:Amniotic Fluid / Q000166:cytology; D002888:Chromosomes, Human, Pair 19 / Q000235:genetics; D002892:Chromosomes, Human, Pair 22 / Q000235:genetics; D020732:Cytogenetic Analysis; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007231:Infant, Newborn; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014178:Translocation, Genetic / Q000235:genetics*; D014314:Trisomy / Q000175:diagnosis*