title: [Registration of clinical trials: a statement from the International Committee of Medical Journal Editors].
abstract: Altruistic motives and trust are central to scientific investigations involving people. These prompt volunteers to participate in clinical trials. However, publication bias and other causes of the failure to report trial results may lead to an overly positive view of medical interventions in the published evidence available. Registration of randomised controlled trials right from the start is therefore warranted. The International Committee of Medical Journal Editors has issued a statement to the effect that the 11 journals represented in the Committee will not consider publication of the results of trials that have not been registered in a publicly accessible register such as www.clinicaltrials.gov. Patients who voluntarily participate in clinical trials need to know that their contribution to better human healthcare is available for decision making in clinical practice.
authors.forename: C
authors.initials: C
authors.lastname: DeAngelis
authors.forename: J M
authors.initials: JM
authors.lastname: Drazen
authors.forename: F A
authors.initials: FA
authors.lastname: Frizelle
authors.forename: C
authors.initials: C
authors.lastname: Haug
authors.forename: J
authors.initials: J
authors.lastname: Hoey
authors.forename: R
authors.initials: R
authors.lastname: Horton
authors.forename: S
authors.initials: S
authors.lastname: Kotzin
authors.forename: C
authors.initials: C
authors.lastname: Laine
authors.forename: A
authors.initials: A
authors.lastname: Marusic
authors.forename: A J P M
authors.initials: AJ
authors.lastname: Overbeke
authors.forename: T V
authors.initials: TV
authors.lastname: Schroeder
authors.forename: H C
authors.initials: HC
authors.lastname: Sox
authors.forename: M B
authors.initials: MB
authors.lastname: van der Weyden
mesh_terms: D002986:Clinical Trials as Topic / Q000592:standards*; D035081:Editorial Policies; D010506:Periodicals as Topic / Q000592:standards*; D012042:Registries