title: [Obstructive sleep apnea syndrome as a risk factor of glaucomatous neuropathy].
abstract: The consequences of sleep apneas in patients with obstructive sleep apnea (OSA) syndrome may influence the function of visual system. In 21 patients with OSA syndrome (apnea/hypopnea index--AHI 50+/-20) the detailed ophthalmologic studies, including tonometry, biomicroscopic evaluation of the anterior segment of the eye, automatic perimetry and stereoscopic examination of the eye fundus have been performed. In 4 patients (19%) the signs of lesions in the optic tract have been found. These were: defects in visual field caused by glaucoma (primary open-angle glaucoma and normal-tension glaucoma) in 2 patients and defects in visual field (concentric and quadrantic homonymous) caused by diffuse lesions in the cortico-nuclear tract in 2 patients. In patients with the lesions in the optic tract there were severe disorders of breathing during sleep: AHI >60, mean SaO2 at the end of the apneas <86% and minimal SaO2 at the end of the apneas <70%. The authors conclude that in OSA patients there is a high risk of the lesions of the optic tract as a consequence of severe and repetitive hypoxemia during sleep.
authors.affiliation: Kliniki Okulistyki Akademii Medycznej we Wrocławiu.
authors.forename: Marta
authors.initials: M
authors.lastname: Misiuk-Hojło
authors.forename: Anna
authors.initials: A
authors.lastname: Brzecka
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Kobierzycka
authors.forename: Marek
authors.initials: M
authors.lastname: Szaliński
mesh_terms: D000328:Adult; D005260:Female; D005901:Glaucoma / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D009900:Optic Nerve / Q000473:pathology* / Q000503:physiopathology; D009901:Optic Nerve Diseases / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D020181:Sleep Apnea, Obstructive / Q000150:complications*; D014065:Tonometry, Ocular; D058609:Visual Field Tests; D014794:Visual Fields