Antimicrobial effect of Cu(II) complexes containing oxime ligands.
The antibacterial, antifungal and antitubercular activity of Cu(II) complexes was studied. All the complexes have been screened against Staphylococcus aureus, Salmonella typhi, Candida albican, Aspergillus niger, Saccharomyces cerevisiae and H37Rv and found to be more toxic than the parent ligand. The activity increased in the order Cu(5-methyl-2,3-hexanedione dioxime)2 < Cu(5-methyl-3-oximino-hexan-2-o-ne-hydrazone)2 < Cu(5-methyl-3-oximino-hexan-2-one-phenylhydrazone)2.
Donde
K J
KJ
Department of Chemistry, The Institute of Science, 15, Madam Cama Road, Mumbai-400032 India.
Patil
V R
VR
Malve
S P
SP
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D003300:Copper / Q000737:chemistry / Q000494:pharmacology*; D008024:Ligands; D008826:Microbial Sensitivity Tests / Q000706:statistics & numerical data; D010091:Oximes / Q000737:chemistry / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D008024:Ligands; D010091:Oximes; D003300:Copper