Syntheses of stereochemically diverse nine-membered ring-containing biaryls.
[reaction: see text] A library of nine-membered, biaryl-containing rings has been synthesized in parallel on polystyrene macrobeads. Dimeric medium rings were shown to be accessible via a regio- and stereoselective double cyclization.
Krishnan
Shyam
S
Department of Chemistry and Chemical Biology, Howard Hughes Medical Institute, Harvard University, and the Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02138, USA.
Schreiber
Stuart L
SL
D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis*; D003500:Cyclization; D019281:Dimerization; D005707:Gallic Acid / Q000031:analogs & derivatives* / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry*; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis*; D008956:Models, Chemical; D011137:Polystyrenes / Q000737:chemistry; D013237:Stereoisomerism
D001643:Bridged Bicyclo Compounds; D005960:Glucosides; D006841:Hydrocarbons, Aromatic; D011137:Polystyrenes; D005707:Gallic Acid; C087926:tellimagrandin I