Cognitive performance of male adolescents is lower than controls across psychiatric disorders: a population-based study.
OBJECTIVE
Psychiatric patients, as well as humans or experimental animals with brain lesions, often concurrently manifest behavioral deviations and subtle cognitive impairments. This study tested the hypothesis that as a group, adolescents suffering from psychiatric disorders score worse on cognitive tests compared with controls.


METHODS
As part of the assessment for eligibility to serve in the military, the entire, unselected population of 16-17-year old male Israelis undergo cognitive testing and screening for psychopathology by the Draft Board. We retrieved the cognitive test scores of 19 075 adolescents who were assigned any psychiatric diagnosis, and compared them with the scores of 243 507 adolescents without psychiatric diagnoses.


RESULTS
Mean test scores of cases were significantly poorer then controls for all diagnostic groups, except for eating disorders. Effect sizes ranged from 0.3 to 1.6.


CONCLUSIONS
As group, adolescent males with psychiatric disorders manifest at least subtle impairments in cognitive functioning.
Weiser
M
M
Department of Psychiatry, Sheba Medical Center, Tel Hashomer, Israel. mweiser@netvision.net.il
Reichenberg
A
A
Rabinowitz
J
J
Knobler
H Y
HY
Lubin
G
G
Yazvitzky
R
R
Nahon
D
D
Gur
R C
RC
Davidson
M
M
D000293:Adolescent; D003072:Cognition Disorders / Q000175:diagnosis* / Q000453:epidemiology; D015331:Cohort Studies; D015897:Comorbidity; D006801:Humans; D007557:Israel / Q000453:epidemiology; D008297:Male; D008403:Mass Screening; D001523:Mental Disorders / Q000175:diagnosis* / Q000453:epidemiology; D011569:Psychiatric Status Rating Scales