title: Intravaginal naproxen in preterm labour: a preliminary study.
abstract: In a preliminary study, the possibility that local inhibition of postaglandin formation may inhibit preterm labour was examined. An intravaginal cyclo-oxygenase inhibitor, naproxen sodium, 500 mg was used in cases of preterm labour. The gestational ages of the patients were between 27 and 34 weeks, and they included a triplet pregnancy unresponsive to beta-sympathomimetic therapy. Treatment with intravaginal naproxen sodium was associated with prolongation of pregnancy for more than 6 days in five out of seven patients. No untoward fetal or maternal side-effects were detected.
authors.affiliation: Akdeniz University, School of Medicine, Department of Obsterics and Gynaecology, Antalya, Turkey.
authors.forename: G
authors.initials: G
authors.lastname: Elpek
authors.forename: M
authors.initials: M
authors.lastname: Uner
authors.forename: B
authors.initials: B
authors.lastname: Trak
authors.forename: Z
authors.initials: Z
authors.lastname: Akinci
authors.forename: C G
authors.initials: CG
authors.lastname: Zorlu