[Concentration changes of amylase in vitreous humor of acute pancreatitis associated with different postmortem interval in rabbits].
OBJECTIVE
To investigate concentration changes of amylase in rabbits vitreous humor of acute pancreatitis associated with postmortem different interval.


METHODS
To induce animal model of acute pancreatitis with sodium taurocholate, observed concentration changes of amylase after different postmortem interval, then compared with normal.


RESULTS
The concentration of amylase in vitreous humor of rabbit 24h after death were related to postmortem interval significantly; The concluded formulae of the relationship between postmortem interval and amylase concentration is y=8.7420+0.7699x-0.0083x2 (R2=92.62792, F=14.89734, P=0.001).


CONCLUSIONS
Concentration changes of amylase in vitreous humor of acute pancreatitis associated with postmortem interval may provide a new sensitive and objective method for the forensic early injury time estimation.
Li
Xing-biao
XB
Department of Forensic Medicine, Wenzhou Medical College, Wenzhou 325027, China.
Zhang
Hai-yan
HY
Shao
Li-ming
LM
D000681:Amylases / Q000032:analysis*; D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D008297:Male; D010195:Pancreatitis / Q000139:chemically induced / Q000201:enzymology*; D011180:Postmortem Changes; D011817:Rabbits; D013053:Spectrophotometry / Q000379:methods; D013656:Taurocholic Acid; D013997:Time Factors; D014822:Vitreous Body / Q000737:chemistry*
D013656:Taurocholic Acid; D000681:Amylases