title: Regression methods for cost-effectiveness analysis with censored data.
abstract: A system of seemingly unrelated regression equations is proposed for prognostic factor adjustment and subgroup analysis when comparing two groups in a cost-effectiveness analysis with censored data. Because of the induced dependent censoring on costs and quality-adjusted survival, inverse probability weighting is employed for parameter estimation. The method is illustrated with data from two recent examples using both survival time and quality-adjusted survival time as the measures of effectiveness.
authors.affiliation: Program in Population Health Sciences, Research Institute, Hospital for Sick Children, 555 University Avenue, Toronto, ON, Canada M5G 1X8. willana@mcmaster.ca
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Willan
authors.forename: D Y
authors.initials: DY
authors.lastname: Lin
authors.forename: Andrea
authors.initials: A
authors.lastname: Manca
mesh_terms: D000638:Amiodarone / Q000191:economics; D000889:Anti-Arrhythmia Agents / Q000191:economics; D002170:Canada; D003362:Cost-Benefit Analysis / Q000379:methods*; D017147:Defibrillators, Implantable / Q000191:economics; D005260:Female; D006323:Heart Arrest / Q000517:prevention & control; D006801:Humans; D007045:Hysterectomy, Vaginal / Q000191:economics; D010535:Laparoscopy / Q000191:economics; D008297:Male; D015233:Models, Statistical; D019057:Quality-Adjusted Life Years; D016032:Randomized Controlled Trials as Topic / Q000191:economics*; D016019:Survival Analysis
chemical_list: D000889:Anti-Arrhythmia Agents; D000638:Amiodarone