[Endoscopic treatment of vesicoureteral reflux].
OBJECTIVE
Endoscopic subureteral injection of tissue-augmenting substances, a 15-minute outpatient procedure has become an alternative to long-term antibiotic prophylaxis and surgical intervention in the treatment of vesicoureteral reflux (VUR) in children.


METHODS
We searched MEDLINE using the words: vesicoureteral reflux, treatment, the long-term results of endoscopic treatment of reflux. We summarized the worldwide data regarding endoscopic treatment of VUR using various tissue-augmenting substances presently available.


RESULTS
In terms of effectiveness and long-term successful results, polytetrafluoroethylene is still the most reliable injectable material for the endoscopic treatment of VUR. However, Dextranomer/hyaluronic acid copolymer (Deflux) is a new promising tissue augmenting substance which might be able to replace Teflon in the endoscopic treatment of reflux in terms of a similar to Teflon reflux cessation rate and exhibiting no evidence of migration.


CONCLUSIONS
Endoscopic subureteral polytetrafluoroethylene injection is a simple and effective outpatient procedure for in the treatment of vesicoureteral reflux. No long-term morbidity was observed in our patients with small amounts of injectable polytetrafluoroethylene.
Chertin
Boris
B
Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel. bchertin@yahoo.com
Fridmans
Alon
A
Koulikov
Dmitry
D
Abu-Arafeh
Waeil
W
Zilberman
Moshe
M
Hadas-Halpern
Irit
I
Farkas
Amicur
A
D001672:Biocompatible Materials; D004724:Endoscopy / Q000379:methods*; D006801:Humans; D011138:Polytetrafluoroethylene; D016896:Treatment Outcome; D014718:Vesico-Ureteral Reflux / Q000175:diagnosis / Q000601:surgery*
D001672:Biocompatible Materials; D011138:Polytetrafluoroethylene