title: [Hemophagocytic syndrome complicating adult's seropositive rheumatoid arthritis].
abstract: BACKGROUND
  Macrophage activation syndrome (MAS) is a severe complication of chronic rheumatic diseases, particularly juvenile rheumatoid arthritis. However, MAS is rarely described in adult rheumatoid polyarthritis.
  
  
  METHODS
  We report a case of MAS complicating a seropositive rheumatoid polyarthritis after 20 years of evolution. Pancytopenia with fever, renal failure and hepatic dysfunction revealed the disease that was confirmed by multiple macrophages and monocytes invading the bone marrow specimen.
  
  
  CONCLUSIONS
  Outcome has been spectacular under corticosteroids.
authors.affiliation: Clinique médicale 1, CHU A.-Le-Dantec, Dakar, Sénégal. niangabdou@yahoo.com <niangabdou@yahoo.com>
authors.forename: A
authors.initials: A
authors.lastname: Niang
authors.forename: S
authors.initials: S
authors.lastname: Diallo
authors.forename: M M
authors.initials: MM
authors.lastname: Ka
authors.forename: A
authors.initials: A
authors.lastname: Pouye
authors.forename: S
authors.initials: S
authors.lastname: Diop
authors.forename: S
authors.initials: S
authors.lastname: Ndongo
authors.forename: T M
authors.initials: TM
authors.lastname: Diop
mesh_terms: D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D015616:Histiocytosis, Non-Langerhans-Cell / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone