[Structure identification of two new cerebrosides from Helicia nilagirica Beed].
OBJECTIVE
To study the bioactive components from Helicia nilagirica.


METHODS
Compounds were separated with a combination of multi-chromatography. Their chemical structures were determined on the basis of spectral analysis and chemical evidence.


RESULTS
Two compounds were isolated from the leaves of Helicia nilagirica. Compound 1 was elucidated as 1-O-3-D-glucopyranosyl-(2S,3S,4R,8Z)-2-[(2'R)-2'-hyd roxylignocenoyl-amino]-8-octadecene-1, 3, 4-triol. Compound 2 was an analogue of 1.


CONCLUSIONS
The two compounds are new cerebrosides.
Wu
Tong
T
Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, China. Tongwu8@hotmail.com
Kong
De-Yun
DY
Li
Hui-Ting
HT
D002554:Cerebrosides / Q000737:chemistry / Q000302:isolation & purification*; D005963:Glucosylceramides / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D039105:Proteaceae / Q000737:chemistry*
C494584:1-O-glucopyranosyl-2-(2'-hydroxylignocenoylaminio)-8-octadecene-1,3,4-triol; D002554:Cerebrosides; D005963:Glucosylceramides