[Clinico-neurophysiologic and experimental study of the peculiarities of adamantan-sulphate treatment in Parkinson's disease].
An experimental investigation of parkinsonism in rats and patients with initial forms of Parkinson's disease was performed by using methods of electromyography and electroneuromyography. Neurophysiologic peculiarities of reorganization of peripheral neuromotor apparatus and criteria for treatment efficacy were detected. The results obtained in the study allowed evaluating of an adequacy of adamantan-sulphate therapy either in the animal experiments and in patients with Parkinson's disease.
Avakian
G N
GN
Voronina
T A
TA
Val'dman
E A
EA
Nerobkova
L N
LN
Katunina
E A
EA
Samoĭlova
E V
EV
D000368:Aged; D000547:Amantadine / Q000494:pharmacology* / Q000627:therapeutic use*; D000818:Animals; D004195:Disease Models, Animal; D015259:Dopamine Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D004576:Electromyography / Q000295:instrumentation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000187:drug effects; D010300:Parkinson Disease / Q000175:diagnosis / Q000188:drug therapy*; D051381:Rats; D012720:Severity of Illness Index
D015259:Dopamine Agents; D000547:Amantadine