title: Etiology of cerebral palsy.
abstract: OBJECTIVE
  To register the prevalence of cerebral palsy (CP) and determine etiological factors for the condition.
  
  
  METHODS
  Population based study with registration of CP-cases in children born during the 30-year period 1970-99. Cases with postneonatal etiology were excluded.
  
  
  RESULTS
  166 CP-cases were registered among 70 824 children, a prevalence of 2.3 per 1000 live born infants. The prevalence did not change significantly during the period. 66 (40%) were low birthweight infants (LBWIs; <2500 g), and 100 (60%) normal birthweight infants (NBWIs; > or = 2500 g). The origin was classified as prenatal in 37 (22%), perinatal/neonatal in 78 (47%) and unclassifiable in 51 (31 %). In LBWIs 39/66 (59%) had a perinatal/neonatal etiology, most frequently intra- or periventricular hemorrhages (IVH/PVH) and/or periventricular leukomalacia (PVL) or cerebral infarctions (CI) (17; 44%). In NBWIs 39/100 (39%) had a perinatal etiology, most frequently hypoxic-ischemic encephalopathy (HIE) (31; 79%).
  
  
  CONCLUSIONS
  In a substantial percentage of CP-cases perinatal/neonatal brain injury was classified as the cause. Among these IVH/PVH/PVL/CI dominated in LBWIs, while HIE dominated in NBWIs. Our data may point to preventability of a larger part of CP than earlier suggested.
authors.affiliation: Department of Paediatrics, Vestfold Hospital Tønsberg, Norway. alf.meberg@siv.no
authors.forename: Alf
authors.initials: A
authors.lastname: Meberg
authors.forename: Harald
authors.initials: H
authors.lastname: Broch
mesh_terms: D002547:Cerebral Palsy / Q000453:epidemiology* / Q000209:etiology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009664:Norway / Q000453:epidemiology; D015995:Prevalence; D012307:Risk Factors