title: Aziridine sulfides and disulfides as catalysts for the enantioselective addition of diethylzinc to aldehydes.
abstract: Chiral aziridine sulfides and disulfides were synthesized from readily available and inexpensive R-cysteine by a Mitsunobu reaction; their application in the addition of diethylzinc to aldehydes provides secondary alcohols with up to 99% ee and S-configuration.
authors.affiliation: Departamento de Química, Universidade Federal de Santa Maria, 97105-900-Santa Maria-RS, Brazil. albraga@quimica.ufsm.br
authors.forename: Antonio L
authors.initials: AL
authors.lastname: Braga
authors.forename: Priscila
authors.initials: P
authors.lastname: Milani
authors.forename: Marcio W
authors.initials: MW
authors.lastname: Paixão
authors.forename: Gilson
authors.initials: G
authors.lastname: Zeni
authors.forename: Oscar E D
authors.initials: OE
authors.lastname: Rodrigues
authors.forename: Elenilson F
authors.initials: EF
authors.lastname: Alves
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis; D000447:Aldehydes / Q000737:chemistry*; D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D013440:Sulfides / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: D000438:Alcohols; D000447:Aldehydes; D001388:Aziridines; D009942:Organometallic Compounds; D013440:Sulfides; C033132:aziridine; D015032:Zinc