title: Advancement of biomarker discovery and validation through the HUPO plasma proteome project.
abstract: The Human Proteome Organization (HUPO) Plasma Proteome Project has mounted a Pilot Phase focussed on key problems essential for standardization of specimen collection, specimen handling, choice of fractionation and analysis technologies, and search engines and databases for protein identifications. This international collaboration will lay the groundwork for many large-scale clinical and epidemiological studies of health and disease.
authors.affiliation: University of Michigan, A510 MSRB I, 1150 W. Medical Center Drive, Ann Arbor, MI 48109-0656, USA. gomenn@umich.edu.
authors.forename: Gilbert S
authors.initials: GS
authors.lastname: Omenn
mesh_terms: D015415:Biomarkers / Q000097:blood*; D030562:Databases, Protein; D006801:Humans; D007391:International Cooperation; D010865:Pilot Projects; D040901:Proteomics / Q000379:methods* / Q000592:standards / Q000639:trends
chemical_list: D015415:Biomarkers