title: [Platelet activation through signal transduction--review].
abstract: Platelet is activated through signal transduction, that mainly includes phospholipase-beta (PLCbeta) pathway, protein tyrosine kinases (PTK) pathway, phosphatidylinositol3-kinase (PI3-K) pathway, mitogen-activated protein kinases (MAPK) pathway, cyclic adenosine monophosphate-protein kinase A (cAMP-PKA) pathway and phospholipase A2 (PLA2) pathway. This article focuses on the relationship between signal transduction and platelet activation.
authors.affiliation: Institute of Blood Transfusion, Academy of Military Medical Sciences, Beijing 100850, China.
authors.forename: Hai Yun
authors.initials: HY
authors.lastname: Pei
authors.forename: Ying
authors.initials: Y
authors.lastname: Han
mesh_terms: D002118:Calcium / Q000378:metabolism; D004792:Enzyme Precursors / Q000378:metabolism; D006160:Guanosine Triphosphate / Q000378:metabolism; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D019869:Phosphatidylinositol 3-Kinases / Q000502:physiology; D015539:Platelet Activation; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D015398:Signal Transduction; D000072377:Syk Kinase; D014841:von Willebrand Factor / Q000502:physiology
chemical_list: D004792:Enzyme Precursors; D047908:Intracellular Signaling Peptides and Proteins; D014841:von Willebrand Factor; D006160:Guanosine Triphosphate; D019869:Phosphatidylinositol 3-Kinases; D011505:Protein-Tyrosine Kinases; C000606896:SYK protein, human; D000072377:Syk Kinase; D002118:Calcium