title: Intrathecal baclofen withdrawal: emergent recognition and management.
abstract: Patients with severe spasticity are frequently encountered in the pediatric emergency department. Intrathecal baclofen therapy is being used increasingly to treat these patients. The purpose of this case series is to illustrate the importance of early recognition and treatment of intrathecal baclofen withdrawal, a potentially life-threatening complication of intrathecal baclofen therapy. Four cases of intrathecal baclofen withdrawal are presented.
authors.affiliation: Department of Pediatrics, Division of Emergency Medicine, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA. noel.zuckerbraun@chp.edu
authors.forename: Noel S
authors.initials: NS
authors.lastname: Zuckerbraun
authors.forename: Susan S
authors.initials: SS
authors.lastname: Ferson
authors.forename: A Leland
authors.initials: AL
authors.lastname: Albright
authors.forename: Eva
authors.initials: E
authors.lastname: Vogeley
mesh_terms: D000293:Adolescent; D000328:Adult; D001418:Baclofen / Q000009:adverse effects*; D002648:Child; D005260:Female; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D009125:Muscle Relaxants, Central / Q000009:adverse effects*; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
chemical_list: D009125:Muscle Relaxants, Central; D001418:Baclofen