title: Immunisation with aluminium-containing vaccine of a child with itching nodule following previous vaccination.
abstract: Vaccination of children with aluminium sensitisation against diphtheria and tetanus presents a problem, since vaccine without aluminium against these potentially serious infectious diseases is no longer available. This case report presents a 7-month-old boy who, after his second immunisation with DTaP-IPV, developed an itching injection site nodule. Before being tested for aluminium sensitisation, he was vaccinated again with DTaP-IPV without developing any reactions. This third vaccine dose was administered intramuscularly.
authors.affiliation: Medical Department, Statens Serum Institute, Artillerivej 5, DK-2300 Copenhagen S., Denmark. sjolin@dadlnet.dk
authors.forename: Marianne Sjølin
authors.initials: MS
authors.lastname: Frederiksen
authors.forename: Hanne
authors.initials: H
authors.lastname: Tofte
mesh_terms: D000276:Adjuvants, Immunologic; D000277:Adjuvants, Pharmaceutic; D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology; D006801:Humans; D007114:Immunization; D007223:Infant; D008297:Male; D011537:Pruritus / Q000209:etiology*; D014611:Vaccination / Q000592:standards*
chemical_list: D000276:Adjuvants, Immunologic; D000277:Adjuvants, Pharmaceutic; D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines