title: Chronic invasive fungal rhinosinusitis: two new cases and review of the literature.
abstract: BACKGROUND
  Chronic invasive fungal rhinosinusitis is rare in the immunocompetent patient. Few cases have been published except for in a specific geographic area (Sudan, India).
  
  
  RESULTS
  We reported two new cases of chronic invasive fungal rhinosinusitis due to Aspergillus, which was successfully treated, to analyze the different clinical, radiological, and mycological criteria.
  
  
  CONCLUSIONS
  Through these two new clinical cases and the analysis of the literature, we suggested, in the absence of general agreement on the surgical and medical management, the current strategies available for this rare pathology. New antifungal drugs seem to be an efficient alternative to classic antifungal agents, especially those that require an extended course of oral therapy for the chronic invasive form.
authors.affiliation: Departments of Ear, Nose, and Throat and Maxillofacial Surgery, C H University Poitiers, Poitiers Cedex, France.
authors.forename: Xavier
authors.initials: X
authors.lastname: Dufour
authors.forename: Catherine
authors.initials: C
authors.lastname: Kauffmann-Lacroix
authors.forename: France
authors.initials: F
authors.lastname: Roblot
authors.forename: Jean Michel
authors.initials: JM
authors.lastname: Goujon
authors.forename: Jean Philippe
authors.initials: JP
authors.lastname: Breux
authors.forename: Jean Claude
authors.initials: JC
authors.lastname: Ferrié
authors.forename: Jean Michel
authors.initials: JM
authors.lastname: Klossek
mesh_terms: D000328:Adult; D000368:Aged; D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy; D001232:Aspergillus fumigatus; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D012852:Sinusitis / Q000175:diagnosis* / Q000188:drug therapy