title: [New insights on the effects of hormone replacement therapy on the breast tissue and the orgnaism].
abstract: Within the last fifteen to twenty years extensive discussions were held about advantages and disadvantages of postmenopausal hormone replacement therapy. Basing on recent data from prospectively randomized studies the long-term application of a combined estrogen-gestagen therapy for general prophylaxis cannot be recommended. Ongoing studies are expected to provide sufficient data to determine regimens for the prevention of osteoporosis, development of cancer, and cardiovascular diseases.
authors.affiliation: Abteilung für Spezielle Gynäkologie, Universitätsklinik für Frauenheilkunde, Wien, Osterreich. waltraud.tayyib-kronfusz@akh-wien.ac.at
authors.forename: Ernst
authors.initials: E
authors.lastname: Kubista
mesh_terms: D001943:Breast Neoplasms / Q000139:chemically induced* / Q000517:prevention & control; D002318:Cardiovascular Diseases / Q000139:chemically induced* / Q000517:prevention & control; D005260:Female; D020249:Hormone Replacement Therapy / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D015663:Osteoporosis, Postmenopausal / Q000517:prevention & control; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D018570:Risk Assessment