title: Presentation of malignant pleural mesothelioma with symptomatic brain metastasis: report of a case.
abstract: Central nervous system metastases from diffuse malignant pleural mesothelioma are rare. Here we describe a patient without known asbestos exposure who presented with chest pain, increasing shortness of breath and persistent headache. Evaluation found biphasic malignant mesothelioma of the right hemithorax and a single brain metastasis confirmed by computed tomography. This represents only the second case of a patient with pleural mesothelioma presenting with symptomatic central nervous system metastases.
authors.affiliation: Division of Radiation Oncology, Marshfield Clinic, Marshfield, WI 54481, USA. Huncharek.Michael@MarshfieldClinic.org
authors.forename: Michael
authors.initials: M
authors.lastname: Huncharek
authors.forename: Ali
authors.initials: A
authors.lastname: Bseiso
authors.forename: Lawrence
authors.initials: L
authors.lastname: Hutchins
authors.forename: John
authors.initials: J
authors.lastname: Warner
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary; D010997:Pleural Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed