Evidence for brain-derived neurotrophic factor-like neuropeptide in brain of the silk moth Bombyx mori during postembryonic periods.
Brain-derived neurotrophic factor-like neuropeptide is produced in the brain of the silk moth, Bombyx mori. Immunocytochemical studies of brain and retrocerebral complex of larvae, prepupae, pupae and adults showed that four pairs of median neurosecretory cells and six pairs of lateral neurosecretory cells which had different immunoreactivities to BDNF peptide. Day-1 adult brains showed no evidence of neurons stained by anti-BDNF antibodies. Those reactivities, which were much stronger in median cells than in lateral cells, were the weakest in an earliest larval stage and a latest pupal stage but the strongest in late larval stage. Median neurosecretory cells projected their axons into the contralateral corpora allata by decussation in the median region, nerve corpora cardiaca (NCC) I, and nerve corpora allata (NCA) I, whereas lateral neurosecretory cells extended their axons to the ipsilateral corpora allata via NCC II and NCA I.
Park
Chan Woo
CW
School of Life Sciences and Biotechnology, Korea University, Anam-dong, Sungbuk-gu, Seoul 136-701, Korea.
Kim
Jin Hee
JH
Kim
Kang Min
KM
Hwang
Jae Sam
JS
Kang
Seok Woo
SW
Kang
Ho Suck
HS
Cho
Byung Pil
BP
Yu
Chai Hyeock
CH
Kim
Hak Ryul
HR
Lee
Bong Hee
BH
D000818:Animals; D012831:Bombyx / Q000254:growth & development*; D001923:Brain Chemistry; D019208:Brain-Derived Neurotrophic Factor / Q000235:genetics / Q000378:metabolism*; D003335:Corpora Allata / Q000166:cytology; D007150:Immunohistochemistry; D007814:Larva / Q000378:metabolism; D008675:Metamorphosis, Biological; D008954:Models, Biological; D009474:Neurons / Q000166:cytology / Q000378:metabolism; D009479:Neuropeptides / Q000235:genetics / Q000378:metabolism*; D011679:Pupa / Q000378:metabolism; D011994:Recombinant Proteins / Q000378:metabolism
D019208:Brain-Derived Neurotrophic Factor; D009479:Neuropeptides; D011994:Recombinant Proteins