title: Cullin-containing E3 ubiquitin ligases in plant development.
abstract: In eukaryotes, the ubiquitin-proteasome system participates in the control of signal transduction events by selectively eliminating regulatory proteins. E3 ubiquitin ligases specifically bind degradation substrates and mediate their poly-ubiquitylation, a prerequisite for their degradation by the 26S proteasome. On the basis of the analysis of the Arabidopsis genome sequence, it is predicted that there are more than 1000 E3 ubiquitin ligases in plants. Several types of E3 ubiquitin ligases have already been characterized in eukaryotes. Recently, some of these E3 enzymes have been implicated in specific plant signaling pathways.
authors.affiliation: Centre for Plant Molecular Biology, Developmental Genetics, Auf der Morgenstelle 5, 72076 Tübingen, Germany. claus.schwechheimer@zmbp.uni-tuebingen.de
authors.forename: Claus
authors.initials: C
authors.lastname: Schwechheimer
authors.forename: Luz Irina A
authors.initials: LI
authors.lastname: Calderon Villalobos
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism; D029681:Arabidopsis Proteins / Q000378:metabolism; D050976:Basic-Leucine Zipper Transcription Factors; D002352:Carrier Proteins / Q000378:metabolism; D018797:Cell Cycle Proteins / Q000378:metabolism; D044842:Cullin Proteins / Q000378:metabolism; D004268:DNA-Binding Proteins; D005030:Ethylenes / Q000378:metabolism; D005875:Gibberellins / Q000378:metabolism; D047908:Intracellular Signaling Peptides and Proteins; D008958:Models, Molecular; D009687:Nuclear Proteins / Q000378:metabolism; D010940:Plant Proteins; D015398:Signal Transduction; D014157:Transcription Factors / Q000378:metabolism; D044767:Ubiquitin-Protein Ligases / Q000378:metabolism*
chemical_list: D029681:Arabidopsis Proteins; D050976:Basic-Leucine Zipper Transcription Factors; D002352:Carrier Proteins; D018797:Cell Cycle Proteins; D044842:Cullin Proteins; C088435:DET1 protein, Arabidopsis; D004268:DNA-Binding Proteins; C106987:EIN3 protein, Arabidopsis; D005030:Ethylenes; C109555:GAI protein, Arabidopsis; D005875:Gibberellins; C109254:HY5 protein, Arabidopsis; C457459:HYH protein, Arabidopsis; D047908:Intracellular Signaling Peptides and Proteins; D009687:Nuclear Proteins; D010940:Plant Proteins; D014157:Transcription Factors; C036216:ethylene; C007842:gibberellic acid; C471983:AT2G32950 protein, Arabidopsis; D044767:Ubiquitin-Protein Ligases