title: Economic evaluation of a short-course intensive rehabilitation program in patients with intermittent claudication.
abstract: OBJECTIVE
  The aim of this study was to provide cost-description and cost-effectiveness of a short-course intensive in-hospital rehabilitation program in patients with intermittent claudication.
  
  
  METHODS
  Costs per case treated were calculated according to a local standard protocol including diagnostic evaluation of peripheral arterial disease and other related cardiovascular conditions, physical training, and secondary prevention. Three additional less structured scenarios were also evaluated.
  
  
  RESULTS
  All 107 enrolled patients (males 91%, mean age 65+/-8 years) completed the program (4-week duration; twice a day walking exercise) and showed significant increases in walking performance, as evaluated by constant treadmill-test. At admission, the mean values of initial claudication distance (ICD) and absolute claudication distance (ACD) were 150+/-111 and 432+/-327 m, respectively. At the end of the program, 12 (11%) patients completed the treadmill test without pain, while 31 (29%) completed the test without stopping due to maximal pain. Among the remaining 64 (60%) patients, the ICD and ACD increased by 137% and 112%, respectively. The cost per case treated ranged from Euro 1733.2 (standard protocol) to Euro 918.9 (physical training only). By adding the cost of hospitalization and indirect costs, the same costs ranged from Euro 4626.2 to Euro 3811.9. The average cost to walk one additional meter without pain as a result of the rehabilitation program was Euro 57.5, while the cost to walk one additional meter before stopping was Euro 27. As showed by sensitivity analysis, the maintenance of the expected level of treatment success was crucial for program's cost-effectiveness.
  
  
  CONCLUSIONS
  From the societal viewpoint, short-course intensive rehabilitation may be cost-effective in patients with stable intermittent claudication and could be considered in decision models evaluating different therapeutic options.
authors.affiliation: Division of Cardiology, Section of Angiology, IRCCS Salvatore Maugeri Foundation, Institute of Tradate (Varese), Italy. mambrosetti@fsm.it
authors.forename: M
authors.initials: M
authors.lastname: Ambrosetti
authors.forename: M
authors.initials: M
authors.lastname: Salerno
authors.forename: S
authors.initials: S
authors.lastname: Boni
authors.forename: G
authors.initials: G
authors.lastname: Daniele
authors.forename: R
authors.initials: R
authors.lastname: Tramarin
authors.forename: R F E
authors.initials: RF
authors.lastname: Pedretti
mesh_terms: D000368:Aged; D003362:Cost-Benefit Analysis; D005081:Exercise Therapy / Q000191:economics*; D005260:Female; D017721:Hospital Costs; D006760:Hospitalization / Q000191:economics; D006801:Humans; D007383:Intermittent Claudication / Q000191:economics* / Q000534:rehabilitation*; D007558:Italy; D008297:Male