[The model of height prognosis in children with growth hormone deficiency].
The authors present a test for a prognosis of height in children with somatotropic hypofunction of the hypophysis treated with growth hormone. A statistic analysis of the height prognosis was performed on support of a model. With support of the examinations and the received results the following conclusions are proposed: 1. The prognosis of the final height in girls treated with growth hormone was statistically significantly lower than boys. 2. The longer the time of therapy with growth hormone the significantly higher the prognosis of height in these children. 3. In spite of 3 years period of growth hormone therapy even with the dose of 0.7 UJ rhGH the children do not achieve calculated prognosis of height. 4. Further examinations are necessary including more children with total or partial growth hormone deficiency with a longer duration of the observation. 5. An analysis of the final height in children after interruption of the growth hormone therapy at the age of 18 years is necessary.
Kostecka
Lidia
L
Klinika Endokrynologii i Diabetologii Wieku Rozwojowego AM we Wrocławiu, Wrocław, Poland.
Wasikowa
Renata
R
Noczyńska
Anna
A
Filipowski
Henryk
H
D000293:Adolescent; D041923:Adolescent Development / Q000187:drug effects*; D001827:Body Height / Q000187:drug effects*; D002648:Child; D002657:Child Development / Q000187:drug effects*; D002675:Child, Preschool; D005260:Female; D006130:Growth Disorders / Q000188:drug therapy* / Q000453:epidemiology; D019382:Human Growth Hormone / Q000172:deficiency* / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008962:Models, Theoretical; D011044:Poland / Q000453:epidemiology; D011379:Prognosis; D013997:Time Factors; D016896:Treatment Outcome
D019382:Human Growth Hormone