Idiopathic hypercalcemia and eosinophilic fasciitis: a novel association.
A 15 year-old boy presented with moderate hypercalcemia (serum calcium 3.35 mmol/l) and eosinophilic fasciitis. An extensive search for a cause of hypercalcemia or underlying malignancy proved negative. Glucocorticoid treatment resulted in significant clinical improvement and resolution of the hypercalcemia. This report describes the novel association of hypercalcemia with eosinophilic fasciitis, with potential implications for the role of inflammatory mediators.
Rutter
Meilan M
MM
Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. meilan.rutter@cchmc.org
Prahalad
Sampath
S
Passo
Murray
M
Backeljauw
Philippe F
PF
D000293:Adolescent; D001774:Blood Chemical Analysis; D004802:Eosinophilia / Q000150:complications / Q000175:diagnosis*; D005208:Fasciitis / Q000150:complications / Q000175:diagnosis*; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D006934:Hypercalcemia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D008297:Male; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
D005938:Glucocorticoids