title: Minimization of sample size when comparing two small probabilities in a non-inferiority safety trial.
authors.forename: Joachim
authors.initials: J
authors.lastname: Röhmel
authors.forename: Gernot
authors.initials: G
authors.lastname: Wassmer
mesh_terms: D017322:Clinical Trials, Phase II as Topic / Q000379:methods*; D004341:Drug Evaluation / Q000379:methods*; D006801:Humans; D012107:Research Design; D018401:Sample Size