[Non-penetrating deep sclerectomy in the treatment of advanced cases of open angle glaucoma].
OBJECTIVE
The purpose of the paper was to examine the efficacy of non-penetrating deep sclerectomy (NPDS) with sodium hyaluronate implants and mitomycin C in the treatment of advanced cases of open angle glaucoma.


METHODS
Thirty-five eyes of 35 patients with medically uncontrolled advanced open angle glaucoma were retrospectively analyzed. Visual acuity and intraocular pressure measurement were performed before and after surgery at 1 and 7 days and 1, 6 and 12 months. Visual field was analyzed before and 12 months after surgery.


RESULTS
The mean preoperative intraocular pressure was 27+/-3.1 mm Hg and 18.1+/-1.5 at 12 month after surgery (p<0.05). Visual acuity decreased more than two rows on Snellen chart in 4 patients. Visual field analysis shows mean defect MD--17+/-5.2 before surgery and 20.1+/-6.2 after 12 month of follow up (p>0.05). Complete success rate defined as an IOP lower than 21 mmHg without medications was 51%. In 3 eyes we performed needling and in 8 goniopuncture. Postoperative complications included hyphaema in 3 eyes, choroidal detachment in 1 eye, bleb fibrosis in 2 eyes.


CONCLUSIONS
1. Deep sclerectomy with SK-GEL implant and antimetabolites provided good reasonable control of intraocular pressure. 2. In uncomplicated cases it let us achieve stabilization of the visual field.
Gierek-Lapińska
Ariadna
A
Kliniki Okulistyki Slaskiej Akademii Medycznej w Katowicach.
Leszczyński
Rafał
R
Wróbel
Andrzej
A
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D006820:Hyaluronic Acid / Q000627:therapeutic use*; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000627:therapeutic use*; D012189:Retrospective Studies; D012590:Sclera / Q000601:surgery*; D012599:Sclerostomy / Q000379:methods*; D013997:Time Factors; D016896:Treatment Outcome; D014792:Visual Acuity / Q000187:drug effects
D000900:Anti-Bacterial Agents; D016685:Mitomycin; D006820:Hyaluronic Acid