title: [Isolation and characterization of active compounds from Aloe vera with a possible role in skin protection].
abstract: Aloe vera is widely used in food supplements, beverages, pharmaceuticals, and cosmetics. It has been long recognized as an effective natural remedy for its wound-healing properties and its positive influence on other inflammatory skin disorders. Major proteins and mono- and polysaccharides were identified and analysed from Aloe vera commercial extract. Molecular weight of proteins calculated from the sets of molecular weight reference standards, ranged from 70 kDa for the largest to 14 kDa for the smallest ones. IR spectral analysis of the carbohydrate fraction shows that the main carbohydrate copound is acetylated (1 --> 4)-beta-D-mannan substituated with D-galactose and D-glucose. The results have shown that proteins and polysaccharides are a necessary component in the study of biological activity of Aloe vera leaf extract.
authors.affiliation: Katedra farmakognózie a botaniky, Farmaceutickej faculty, Univerzity Komenského, Bratislava. kostalova@fpharm.uniba.sk
authors.forename: D
authors.initials: D
authors.lastname: Kostálová
authors.forename: L
authors.initials: L
authors.lastname: Bezáková
authors.forename: M
authors.initials: M
authors.lastname: Oblozinský
authors.forename: A
authors.initials: A
authors.lastname: Kardosová
mesh_terms: D000504:Aloe / Q000737:chemistry*; D006801:Humans; D009195:Peroxidase / Q000032:analysis; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D010940:Plant Proteins / Q000032:analysis; D011134:Polysaccharides / Q000032:analysis; D012867:Skin / Q000187:drug effects
chemical_list: D010936:Plant Extracts; D010940:Plant Proteins; D011134:Polysaccharides; D009195:Peroxidase