[Purification of viral drugs for development of diagnostic aids of Teschen disease].
Optimal methods of purification and concentration of teschevirus strain of the pigs of the first serotype "Chernigivsky-2372" have been chosen for development of the set of Teschen pig discase diagnosticums. It has been established that differential centrifugation with following ultracentrifugation in the gradient of saccharose density permits to deprive viruses from host cell proteins, empty virus capsides and defect virus particles. That is the method fit for purification of virus preparations for the solid-phase immunoenzyme analysis.
Bova
T O
TO
Soroka
V I
VI
Derev'ianko
S V
SV
Volkova
I V
IV
Mamchur
O Ie
OIe
D000818:Animals; D004682:Encephalomyelitis, Enzootic Porcine / Q000175:diagnosis*; D004770:Enterovirus / Q000648:ultrastructure; D008854:Microscopy, Electron; D004364:Pharmaceutical Preparations / Q000302:isolation & purification*; D013552:Swine; D014461:Ultracentrifugation
D004364:Pharmaceutical Preparations