[Carbogen combined with drugs in the treatment of sudden deafness].
OBJECTIVE
To analyze the clinical efficiency and study the possible mechanism of the carbogen combined with drugs in the treatment of sudden deafness.


METHODS
Fifty-two patients with sudden deafness were divided into two groups: Twenty-six cases received carbogen (5% CO2 - 95% O2) combined with drug therapeutics of a course of intravenous administration of dexamethasone, vitaminB, low molecular dextran, salviae miltiorrhizae, and intake vitaminC, vitaminE, et al and the other 26 cases received the drugs only. The clinical effects were compared.


RESULTS
The total effective rate was 76.92% in the carbogen group and 50.00% in the control group. The difference was significant between the two groups. The recovery time in the carbogen group was 3-14 days while in the control group was 6-23 days.


CONCLUSIONS
The efficiency of carbogen ombined with drugs is superior to drug therapeutics in the treatment of sudden deafness.
Ni
Yusu
Y
Department of Otorhinolaryngology-Head and Neck Surgery, Huashan Hospital of Fudan University, Shanghai, 200040, China.
Zhao
Xia
X
D000293:Adolescent; D000328:Adult; D000368:Aged; D002245:Carbon Dioxide / Q000627:therapeutic use*; D002648:Child; D003131:Combined Modality Therapy; D003907:Dexamethasone / Q000627:therapeutic use; D005938:Glucocorticoids / Q000627:therapeutic use; D003639:Hearing Loss, Sudden / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D018696:Neuroprotective Agents / Q000627:therapeutic use; D010100:Oxygen / Q000627:therapeutic use*; D012138:Respiratory Therapy; D014665:Vasodilator Agents / Q000627:therapeutic use
D005938:Glucocorticoids; D018696:Neuroprotective Agents; D014665:Vasodilator Agents; D002245:Carbon Dioxide; D003907:Dexamethasone; C011700:carbogen; D010100:Oxygen