Luminescent nanoparticle probes for bioimaging.
Bioimaging with luminescent nanoparticle probes have recently attracted widespread interest in biology and medicine. In comparison with commonly used organic dyes, luminescent nanoparticles are better in terms of photostability and sensitivity. These optical features of nanoparticle probes are critical for real time tracking and monitoring of biological events in the cellular level, which may not be accomplished using regular fluorescent dyes. Nanoparticle probes are also shown highly suitable for immunoassay and other diagnostic and therapeutic applications. In this article, we describe a variety of optical nanoparticle probes such as quantum dots, metal nanoparticles, dye-doped nanoparticles etc. for bioimaging applications.
Santra
Swadeshmukul
S
Department of Neurological Surgery, University of Florida, Gainesville, Florida 32610, USA.
Xu
Jinsheng
J
Wang
Kemin
K
Tan
Weihong
W
D005456:Fluorescent Dyes / Q000494:pharmacology*; D007118:Immunoassay; D046529:Microscopy, Electron, Transmission / Q000379:methods; D008856:Microscopy, Fluorescence / Q000379:methods*; D036103:Nanotechnology / Q000379:methods*; D011108:Polymers / Q000737:chemistry; D045663:Quantum Dots; D012825:Silicon / Q000737:chemistry; D013997:Time Factors
D005456:Fluorescent Dyes; D011108:Polymers; D012825:Silicon