title: Using yeast to shed light on DNA damaging toxins and irradiation.
abstract: This unlikely tale of research and development takes us from a Pacific jellyfish to fluorescent green yeast in space, via the high tech world of pharmaceutical screening and an encounter with the YETI. It charts the history of academic research project that through multidisciplinary collaboration and innovation has led to a commercial venture with applications in a number of diverse fields.
authors.affiliation: Department of Instrumentation and Analytical Science, University of Manchester Institute of Science and Technology, Manchester, UK. a.knight@umist.ac.uk
authors.forename: Andrew W
authors.initials: AW
authors.lastname: Knight
mesh_terms: D000337:Aerospace Medicine; D015374:Biosensing Techniques; D004271:DNA, Fungal / Q000187:drug effects* / Q000528:radiation effects; D004353:Drug Evaluation, Preclinical; D004784:Environmental Monitoring / Q000379:methods; D049452:Green Fluorescent Proteins / Q000235:genetics; D006801:Humans; D009152:Mutagenicity Tests / Q000295:instrumentation; D009153:Mutagens / Q000494:pharmacology; D015003:Yeasts / Q000235:genetics*
chemical_list: D004271:DNA, Fungal; D009153:Mutagens; D049452:Green Fluorescent Proteins