title: Regional variability in population acute myocardial infarction cumulative incidence and mortality rates in Spain 1997 and 1998.
abstract: BACKGROUND
  Myocardial infarction (MI) incidence and mortality display a high geographic variation.
  
  
  OBJECTIVE
  The objective of the present study was to analyze MI mortality, cumulative incidence rate variability in seven regions of Spain from 1997 to 1998.
  
  
  RESULTS
  Standardized methods were used to identify, find, register, and classify MI cases that were classified as definite, possible, insufficient-data MI, and non-MI. The total population of the seven monitored regions was 7,364,682 inhabitants. Of the 11,256 cases fulfilling eligibility criteria to investigate, 10,660 were selected to calculate MI rates: 6554 (61.5%) non-fatal definite MI, 1179 (11.1%) fatal definite MI, 1859 (17.4%) fatal possible MI, 1068 (10.0%) fatal cases with insufficient data. The IBERICA 25-74 years age-standardized cumulative incidence rates for men and women, were 207 (range: 175-252) and 45 (range: 36-65) per 100,000, respectively. The age-standardized mortality rates for men and women, were 73 (range: 62-94) and 20 (range: 13-29) per 100,000, respectively. Age-standardized case-fatality was 31.4 and 24.2% in men aged 25-74 and 35-64 years, respectively, and 32.7 and 27.0%, respectively, in women.
  
  
  CONCLUSIONS
  MI cumulative incidence and mortality rates are low compared with other industrialized countries but, vary considerably among regions in a Mediterranean country like Spain.
authors.affiliation: Unitat de Lipids i Epidemiologia Cardiovascular, Institut Municipal d'Investigació Medica, Barcelona, Spain. jmarrugat@imim.es
authors.forename: Jaume
authors.initials: J
authors.lastname: Marrugat
authors.forename: Roberto
authors.initials: R
authors.lastname: Elosua
authors.forename: Elena
authors.initials: E
authors.lastname: Aldasoro
authors.forename: María José
authors.initials: MJ
authors.lastname: Tormo
authors.forename: Hermelinda
authors.initials: H
authors.lastname: Vanaclocha
authors.forename: Antonio
authors.initials: A
authors.lastname: Segura
authors.forename: Miquel
authors.initials: M
authors.lastname: Fiol
authors.forename: Concepción
authors.initials: C
authors.lastname: Moreno-Iribas
authors.forename: Gloria
authors.initials: G
authors.lastname: Pérez
authors.forename: José María
authors.initials: JM
authors.lastname: Arteagoitia
authors.forename: Lluis
authors.initials: L
authors.lastname: Cirera
authors.forename: Adolfo
authors.initials: A
authors.lastname: Cabadés
authors.forename: Gema
authors.initials: G
authors.lastname: Vega
authors.forename: José Ignacio
authors.initials: JI
authors.lastname: Ayestarán
authors.forename: Vega
authors.initials: V
authors.lastname: García
authors.forename: Iraida
authors.initials: I
authors.lastname: Hurtado-de-Saracho
authors.forename: José
authors.initials: J
authors.lastname: García
authors.forename: Oscar
authors.initials: O
authors.lastname: Zurriaga
authors.forename: Javier
authors.initials: J
authors.lastname: Muñiz
authors.forename: Joan
authors.initials: J
authors.lastname: Sala
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000465:Algorithms; D019049:Developed Countries / Q000706:statistics & numerical data; D005260:Female; D005843:Geography; D006801:Humans; D015994:Incidence; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology* / Q000401:mortality*; D012042:Registries; D017678:Sex Distribution; D013030:Spain / Q000453:epidemiology; D011795:Surveys and Questionnaires