title: [Nonspecific interstitial pneumonitis: a clinicopathologic entity, histologic pattern or unclassified group of heterogeneous interstitial pneumonitis?].
abstract: Nonspecific interstitial pneumonitis (NSIP) initially described by Katzenstein and Fiorelli in 1994, seems to be a distinct clinicopathologic entity among idiopathic interstitial pneumonitis (IIP). Besides different histologic features from other IIP, NSIP is characterized by a better long-term outcome, associated with a better steroids responsiveness than idiopathic pulmonar fibrosis (IPF), where usually were included. Thus, differentiating NSIP from other IIP, namely IPF is very significant, since it has important therapeutic and prognostic implications. NSIP encloses different pathologies, namely those with inflammatory predominance (cellular subtype) or fibrous predominance (fibrosing subtype). NSIP is reviewed and discussed by the authors, after two clinical cases description.
authors.forename: António
authors.initials: A
authors.lastname: Morais
authors.forename: M Conceição Souto
authors.initials: MC
authors.lastname: Moura
authors.forename: M Rosa
authors.initials: MR
authors.lastname: Cruz
authors.forename: Isabel
authors.initials: I
authors.lastname: Gomes
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000145:classification / Q000473:pathology*; D008297:Male; D008875:Middle Aged