title: [A multiple myeloma long term survival case].
abstract: Multiple myeloma is a malignant plasma cells proliferation in the bone marrow leading to a monoclonal immunoglobulin hypersecretion. The survival duration of this disease ranges usually from 2 to 3 years. However, as this reported case, a long-term survival remains possible. A 29 year old woman was admitted to the internal medicine department for bone pain, weight loss and pathologic fractures. The clinical examination revealed an anaemia, a spinal compression (D10) and atrophia of quadriceps and gluteus muscle. The radiologic findings observed were multiple fractures. The bone marrow aspiration confirmed the plasmocytosis greater than 50%, with immature plasma cells and other lineages rarefication. The disease belonged to the stage III A of the Salmon and Durie classification. Chemotherapy with melphalan associated to prednisone was started with a two to three months biological and clinical follow-up. This treatment allowed 12 years survival. Because of this variety, the search for new prognostic factors would be relevant.
authors.affiliation: Travail de la Clinique Médicale I CHU A. Le Dantec, Avenue Pasteur, Dakar.
authors.forename: Abdoulaye
authors.initials: A
authors.lastname: Pouye
authors.forename: Mamadou Mourtalla
authors.initials: MM
authors.lastname: Ka
authors.forename: Saïdou
authors.initials: S
authors.lastname: Diallo
authors.forename: Seynabou
authors.initials: S
authors.lastname: Fall
authors.forename: Daouda
authors.initials: D
authors.lastname: Dia
authors.forename: Souhaïbou
authors.initials: S
authors.lastname: Ndongo
authors.forename: Abdoulaye
authors.initials: A
authors.lastname: Leye
authors.forename: Moreira Thérèse
authors.initials: MT
authors.lastname: Diop
mesh_terms: D000328:Adult; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D009101:Multiple Myeloma / Q000628:therapy*; D017741:Survivors; D013997:Time Factors