title: [Study on the potentiation of bone marrow mesenchymal stem cells involved in sebaceous duct formation].
abstract: OBJECTIVE
  To investigate the feasibility of differentiation of bone marrow mesenchymal stem cells (MSCs) into skin appandence.
  
  
  METHODS
  Porcine MSCs were isolated from porcine marrow and grown in vitro. After labeling with BrdU, MSCs were engrafted to porcine skin. At 1, 2, 4 weeks after the transplantation, immunohistochemical examinations were carried out to detect the positive staining of BrdU and cytokeratin.
  
  
  RESULTS
  A few sebaceous duct cells, which expressed cytokeratin, were also BrdU positive, and these cells were considered may to be transplanted MSCs-derived cells.
  
  
  CONCLUSIONS
  Porcine MSCs might have the potential to differentiated into sebaceous duct cells in skin.
authors.affiliation: Department of Stomatology of the Second Affiliated Hospital of Chinese Medical University, Shenyang 110003, China. fuxb@vip.sina.com
authors.forename: Li-jun
authors.initials: LJ
authors.lastname: Fang
authors.forename: Xiao-bing
authors.initials: XB
authors.lastname: Fu
authors.forename: Biao
authors.initials: B
authors.lastname: Cheng
authors.forename: Tong-zhu
authors.initials: TZ
authors.lastname: Sun
authors.forename: Jian-fu
authors.initials: JF
authors.lastname: Li
authors.forename: Rong
authors.initials: R
authors.lastname: Cao
authors.forename: Yu-xin
authors.initials: YX
authors.lastname: Wang
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology*; D002454:Cell Differentiation; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000166:cytology*; D012627:Sebaceous Glands / Q000166:cytology*; D013552:Swine; D013556:Swine, Miniature; D014182:Transplantation, Autologous