title: [beta-blockers in the treatment of hypertension in diabetic patients].
abstract: Cardiovascular diseases and strokes are the main reasons of premature deaths in 70% patients with non insulin-dependent and also insulin-dependent diabetes mellitus. Hypertension is 2 to 3 times more frequent in diabetic patients than in the rest of population. In the guidelines for management of hypertension in diabetes published this year beta-blockers are proposed together with the ACE-inhibitors as the first-choice drugs. The latest studies did not confirm the risk of higher and prolonged hypoglycemia during cardioselective beta-adrenergic blocade, but the insulin-treated diabetics with hypoglycemia episodes in the past should be watched very carefully when given beta-blockers. It is emphasized, that beta-blockers are very useful especially in patients with diabetes mellitus, hypertension and coronary artery disease. In patients after myocardial infarction the advantages with treatment with beta-blockers dominate over the potential risk of adverse drug reactions.
authors.affiliation: Katedra i Klinika Kardiologii AM we Wrocławiu.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Kobusiak-Prokopowicz
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D003920:Diabetes Mellitus / Q000453:epidemiology*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000453:epidemiology*
chemical_list: D000319:Adrenergic beta-Antagonists