title: Detection of ticarcillin-clavulonic acid susceptibility with microdilution method in Citrobacter, Hafnia, Proteus and some gram negative bacteria.
abstract: The broth dilution method has been regarded as a good alternative test for detection of susceptibilities to antimicrobial agents. In this study, the antimicrobial activity of ticarcillin-clavulonic acid (TIM) was investigated by the minimal inhibitory concentration (MIC) method on strains of Aeromonas, Citrobacter, Hafnia, Morganella, Proteus, Pseudomonas and gram negative bacteria isolated from raw milk. The isolate collection included 91 gram negative strains. Fifty-one (56.04%) isolates were found sensitive (MIC < or = 8 microg/ml), 12 (13.19%) isolates were found intermediately sensitive (MIC 16-32 microg/ml), and 28 (30.77%) isolates were found resistant (MIC > or = 64 microg/ml) to TIM.
authors.affiliation: Microbiology Department, Faculty of Science and Arts, Gazi University, Teknikokullar, Ankara, Turkey. guraz@gazi.edu.tr
authors.forename: Güven
authors.initials: G
authors.lastname: Uraz
authors.forename: Ozlem
authors.initials: O
authors.lastname: Oncül
mesh_terms: D000333:Aeromonas / Q000187:drug effects; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002417:Cattle; D002954:Citrobacter / Q000187:drug effects; D002969:Clavulanic Acids / Q000494:pharmacology*; D004754:Enterobacter / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D005516:Food Microbiology; D006092:Gram-Negative Facultatively Anaerobic Rods / Q000187:drug effects*; D020595:Hafnia / Q000187:drug effects; D007709:Klebsiella / Q000187:drug effects; D008826:Microbial Sensitivity Tests / Q000379:methods; D008892:Milk / Q000382:microbiology*; D011511:Proteus / Q000187:drug effects; D013982:Ticarcillin / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D002969:Clavulanic Acids; D004791:Enzyme Inhibitors; C043215:ticarcillin-clavulanic acid; D013982:Ticarcillin