title: Twenty-three years of disease-free survival following cutaneous metastasis from a primary bladder transitional cell carcinoma.
abstract: We present a case of cutaneous metastases from a primary bladder transitional cell carcinoma (TCC), with a prolonged survival of 23 years. Cutaneous metastases from primary bladder TCC are uncommon and, like all metastases, have a poor prognosis. The common modality of treatment of cutaneous metastases from a primary bladder cancer is wide local excision of the metastases followed by combination chemotherapy. Here, we present a case of a solitary cutaneous metastasis from a primary bladder TCC, which was treated with wide local excision and single agent chemotherapy. Twenty-three years on, the patient remains disease and recurrence free.
authors.affiliation: Department of Surgery, Medical School, Newcastle University, Newcastle upon Tyne, UK. bharat.gowardhan@ncl.ac.uk
authors.forename: Bharat
authors.initials: B
authors.lastname: Gowardhan
authors.forename: Marie E
authors.initials: ME
authors.lastname: Mathers
authors.forename: Jeremy G W
authors.initials: JG
authors.lastname: Feggetter
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D002295:Carcinoma, Transitional Cell / Q000556:secondary* / Q000628:therapy; D018572:Disease-Free Survival; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D012878:Skin Neoplasms / Q000556:secondary* / Q000628:therapy; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000628:therapy
chemical_list: D000964:Antimetabolites, Antineoplastic; D008727:Methotrexate