title: [Pancreaticojejunal anastomosis: the "Achilles heel" of pancreaticoduodenectomy].
abstract: This article reviews available data on factors influencing healing of pancreatic anastomosis following pancreaticoduodenectomy. Technical approaches of various techniques of pancreatic anastomosis including pancreaticogastrostomy are discussed and compared. Attention is paid to the other associated risk factors for pancreatic anastomotic leakage such as patient status, as well as morphologic and physiologic peculiarities of pancreatic remnant. The concept of pharmacological prevention of anastomotic leakage is discussed.
authors.affiliation: Clinic of Surgery, Kaunas University of Medicine Hospital, Lithuania.
authors.forename: Antanas
authors.initials: A
authors.lastname: Gulbinas
authors.forename: Giedrius
authors.initials: G
authors.lastname: Barauskas
authors.forename: Juozas
authors.initials: J
authors.lastname: Pundzius
mesh_terms: D000367:Age Factors; D000368:Aged; D000714:Anastomosis, Surgical; D018849:Controlled Clinical Trials as Topic; D005765:Gastrointestinal Agents / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D015201:Meta-Analysis as Topic; D015282:Octreotide / Q000008:administration & dosage / Q000627:therapeutic use; D010179:Pancreas / Q000601:surgery; D010185:Pancreatic Fistula / Q000209:etiology* / Q000517:prevention & control; D016577:Pancreaticoduodenectomy / Q000009:adverse effects / Q000379:methods; D010193:Pancreaticojejunostomy / Q000009:adverse effects / Q000379:methods; D012307:Risk Factors; D013004:Somatostatin / Q000008:administration & dosage / Q000627:therapeutic use; D013270:Stomach / Q000601:surgery
chemical_list: D005765:Gastrointestinal Agents; D013004:Somatostatin; D015282:Octreotide