title: Acute arterial thrombotic purpura complicating varicella and the role of hyperbaric oxygen as an adjunctive therapy.
abstract: Chickenpox is a common infectious disease of the pediatric age group with rare complications such as hemorrhagic varicella and arterial thrombotic purpura. Medical support is the mainstay of treatment in such cases but for the rescue of necrotic tissues, hyperbaric oxygen (HBO) therapy should be applied in addition to anticoagulant intervention. We report an infant with acute arterial thrombotic purpura which developed after varicella eruption and who made full recovery with the help of HBO as an adjunctive treatment modality. Fresh frozen plasma and low molecular weight heparin were given for prolonged prothrombin time and thromboemboli on the 2nd-4th digits of his right foot. Protein C, protein S and factor V levels were found to be normal in our patient. Necrotic lesions on the toes regressed with repeated HBO treatment and amputation was not needed.
authors.affiliation: Department of Pediatrics, Social Security Foundation, Bakirköy Maternity and Children's Training Hospital, Istanbul, Turkey.
authors.forename: Rengin
authors.initials: R
authors.lastname: Siraneci
authors.forename: Nevin
authors.initials: N
authors.lastname: Hatipoğlu
authors.forename: Hüsem
authors.initials: H
authors.lastname: Hatipoğlu
authors.forename: Kadir
authors.initials: K
authors.lastname: Dündar
authors.forename: Leyla
authors.initials: L
authors.lastname: Baygin
authors.forename: Canan
authors.initials: C
authors.lastname: Yildiz
authors.forename: Ozden
authors.initials: O
authors.lastname: Türel
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D002644:Chickenpox / Q000150:complications*; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D006931:Hyperbaric Oxygenation; D007223:Infant; D008297:Male; D011697:Purpura, Thrombotic Thrombocytopenic / Q000150:complications* / Q000628:therapy*
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight