Efficient and mild room temperature reduction of benzophenones under ultrasound irradiation.
Benzophenones without strong electron-releasing substituents were reduced into the corresponding benzhydrols at room temperature in moderate to good yields with Zn-NaOH-95% ethanol under ultrasound irradiation. This method is also propitious to the synthesis of 3-phenylphthalide and its derivates.
Peng
Yanqing
Y
Shanghai Key Laboratory of Chemical Biology, Institute of Pesticides and Pharmaceuticals, East China University of Science and Technology, 130 Meilong Road, P.O. Box 544, Shanghai 200237, China.
Zhong
Wujun
W
Song
Gonghua
G