title: The influence of obstructive sleep apnea on FFR measurements for coronary lesion assessment.
abstract: Fractional flow reserve (FFR) determinations have been demonstrated to be largely independent of changes in systemic hemodynamic changes. Herein, we describe a case of obstructive sleep apnea cyclically altering FFR measurements from normal to abnormal in a patient with an intermediately severe coronary narrowing following treatment for an acute coronary syndrome. To eliminate uncertainty, FFR measurements should be made if possible during suspended respiration.
authors.affiliation: J. Gerard Mudd Cardiac Catheterization Laboratory, St. Louis University Health Sciences Center, 3635 Vista Avenue at Grand Boulevard, St. Louis, MO 63110, USA.
authors.forename: Jeffrey P
authors.initials: JP
authors.lastname: Ciaramita
authors.forename: Walter A
authors.initials: WA
authors.lastname: Parham
authors.forename: Steven
authors.initials: S
authors.lastname: Herrmann
authors.forename: Souheil
authors.initials: S
authors.lastname: Khoukaz
authors.forename: Morton J
authors.initials: MJ
authors.lastname: Kern
mesh_terms: D001783:Blood Flow Velocity; D001794:Blood Pressure / Q000502:physiology; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000502:physiology*; D003327:Coronary Disease / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D003331:Coronary Vessels / Q000502:physiology*; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000502:physiology; D008875:Middle Aged; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000503:physiopathology*; D014655:Vascular Resistance / Q000502:physiology