title: [Antibodies to beta-2 glycoprotein I in serum and aqueous humor of patients with glaucoma and their influence on the static perimetry].
abstract: OBJECTIVE
  The evaluation of the relationships between the antibodies anti beta-2 glycoprotein I in serum and aqueous humor of the glaucoma patients to the visual field defects.
  
  
  METHODS
  48 persons (38 women and 17 men), aged 30-86 (mean age 70), suffering from glaucoma was examined. There were 19 with POAG, 18 with PACG and 11 with PEXG. All patients have undergone trabeculectomy. In plasma and anterior chamber fluid the level of antibodies to beta-2 glycoprotein I classes IgA and IgG were measured using ELISA method (commercial kits produced by Euroimmun), according to producer's instruction. The visual field defects were examined with Humphrey static perimetry. Statistical analysis was performed using Spearman test.
  
  
  RESULTS
  There were no significant correlations between antibodies anti beta-2 glycoprotein I, static perimetry, age and duration of the disease.
  
  
  CONCLUSIONS
  There have not been stated any relationships between the static perimetry to antiphospholipid antibodies level in serum and aqueous humor in patients with glaucoma. It is the preliminary communication.
authors.affiliation: II Kliniki Okulistyki Akademii Medycznej im. prof. Feliksa Skubiszewskiego w Lublinie.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Latalska
authors.forename: Marek
authors.initials: M
authors.lastname: Gerkowicz
authors.forename: Ewa
authors.initials: E
authors.lastname: Kosior-Jarecka
authors.forename: Maria
authors.initials: M
authors.lastname: Kozioł-Montewka
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Pietraś-Trzpiel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001082:Aqueous Humor / Q000276:immunology*; D001323:Autoantibodies / Q000097:blood / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005901:Glaucoma / Q000276:immunology* / Q000503:physiopathology* / Q000601:surgery; D006023:Glycoproteins / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D014130:Trabeculectomy; D058609:Visual Field Tests; D014794:Visual Fields / Q000276:immunology; D053482:beta 2-Glycoprotein I
chemical_list: D001323:Autoantibodies; D006023:Glycoproteins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D053482:beta 2-Glycoprotein I