title: Obstetric management of Klippel-Trenaunay syndrome.
abstract: BACKGROUND
  Klippel-Trenaunay syndrome is a rare congenital disease characterized by extensive cutaneous vascular malformations, venous varicosities, focal abnormalities of the deep venous system, and underlying soft tissue or bony hypertrophy. Given the rarity of the disease, there is little information available to counsel patients with Klippel-Trenaunay syndrome regarding obstetric outcome.
  
  
  METHODS
  We report our experience with 3 patients in whom Klippel-Trenaunay syndrome complicated 4 pregnancies. Successful delivery of a healthy infant at or beyond 36 weeks of gestation was achieved in all pregnancies. One of the 4 pregnancies was complicated by pulmonary embolism.
  
  
  CONCLUSIONS
  Klippel-Trenaunay syndrome was once thought to be a contraindication to pregnancy. With careful management, successful pregnancies can be achieved.
authors.affiliation: Department of Obstetrics & Gynecology, New York University School of Medicine, New York, New York, USA. ar53@nyu.edu
authors.forename: Andrei
authors.initials: A
authors.lastname: Rebarber
authors.forename: Ashley S
authors.initials: AS
authors.lastname: Roman
authors.forename: Daniel
authors.initials: D
authors.lastname: Roshan
authors.forename: Francine
authors.initials: F
authors.lastname: Blei
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D005260:Female; D047109:Fetal Development / Q000502:physiology; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D007715:Klippel-Trenaunay-Weber Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D008991:Monitoring, Physiologic; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis* / Q000188:drug therapy; D011256:Pregnancy Outcome; D011296:Prenatal Diagnosis / Q000379:methods; D035583:Rare Diseases; D012494:Sampling Studies; D012720:Severity of Illness Index
chemical_list: D000925:Anticoagulants