title: Glioblastoma multiforme causing calvarial destruction: an unusual manifestation revisited.
abstract: This report describes invasion of overlying calvaria and soft tissues by a high-grade glioma without macroscopic evidence of dural involvement. The initial radiologic examinations demonstrated a heterogeneous mass in the right frontoparietal region with both extra- and intra-axial components. Inward displacement of the adjacent dura initially prompted consideration for extra-axial lesions such as metastatic lesions, lymphoma, or an aggressive meningioma. The pathologic findings demonstrated a glial cell origin.
authors.affiliation: Department of Radiology, Medical College of Virginia, Richmond, VA, USA.
authors.forename: Vinay
authors.initials: V
authors.lastname: Gheyi
authors.forename: Ferdinand K
authors.initials: FK
authors.lastname: Hui
authors.forename: Egon M
authors.initials: EM
authors.lastname: Doppenberg
authors.forename: William
authors.initials: W
authors.lastname: Todd
authors.forename: William C
authors.initials: WC
authors.lastname: Broaddus
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003399:Craniotomy; D003937:Diagnosis, Differential; D004388:Dura Mater / Q000473:pathology; D005625:Frontal Lobe / Q000473:pathology*; D005909:Glioblastoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D009361:Neoplasm Invasiveness / Q000473:pathology*; D010296:Parietal Lobe / Q000473:pathology*; D012535:Scalp / Q000473:pathology; D012886:Skull / Q000473:pathology*; D014057:Tomography, X-Ray Computed