title: Attenuated adult biphasic shocks for prolonged pediatric ventricular fibrillation: support for pediatric automated defibrillators.
abstract: OBJECTIVE
  To evaluate published data regarding the treatment of prolonged pediatric defibrillation, with special emphasis on the use of attenuated adult biphasic shocks for pediatric defibrillation.
  
  
  METHODS
  Review relevant human and animal literature.
  
  
  RESULTS
  Rhythm analysis algorithms from two manufacturers of automated external defibrillators can accurately distinguish shockable from nonshockable rhythms in children. Theoretical considerations and transthoracic impedance data from animals and children suggest that pediatric defibrillation doses should not necessarily vary in a simple weight-based manner. Two piglet studies have established that an attenuated adult biphasic dosage can be successfully used for 3.5- to 24-kg animals in ventricular fibrillation. One study established that the attenuated adult biphasic dosage was at least as safe and effective as the standard monophasic weight-based dosing.
  
  
  CONCLUSIONS
  This review supports the American Heart Association's new guidelines for pediatric automated external defibrillator usage: "Automated external defibrillators may be used for children 1 to 8 yrs of age who have no signs of circulation. Ideally the device should deliver a pediatric dose. The arrhythmia detection system used in the device should demonstrate high specificity for pediatric shockable rhythms, i.e., it will not recommend delivery of a shock for nonshockable rhythms."
authors.affiliation: University of Arizona Steele Memorial Children's Research Center and Sarver Heart Center, Department of Pediatrics, Tucson, AZ, USA.
authors.forename: Robert A
authors.initials: RA
authors.lastname: Berg
mesh_terms: D000328:Adult; D000818:Animals; D001835:Body Weight; D002648:Child; D002675:Child, Preschool; D004554:Electric Countershock / Q000379:methods*; D006323:Heart Arrest / Q000628:therapy*; D006801:Humans; D007223:Infant; D010372:Pediatrics; D013552:Swine; D014693:Ventricular Fibrillation / Q000628:therapy*