Behçet's disease in Moroccan children: a report of 12 cases.
We report 12 cases of Behçet's disease (BD) in children. The mean age of symptom onset was 12.4 years. Four patients (33.3%) had a past familial history of BD. Clinical manifestations were: oral aphtosis (n = 12), genital aphtosis (n = 9), ocular involvement (n = 9), neuro-Behçet (n = 6), venous thrombosis (n = 4), articular involvement (n = 3), and entero-Behçet (n = 1). All patients but one were initially treated with steroids; three cases with ocular involvement were treated with chlorambucil; and three other cases of neuro-Behçet were treated with cyclophosphamide. After a mean follow-up of 4 years, four patients with neurological involvement developed steroid-dependence with recurrence of symptoms. Four patients had optic atrophy with blindness.
Allali
F
F
Rheumatology B Department, El Ayachi Hospital, Sale, Morocco. fadouaallali@yahoo.fr
Benomar
A
A
Karim
A
A
Lazrak
N
N
Mohcine
Z
Z
El Yahyaoui
M
M
Chkili
T
T
Hajjaj-Hassouni
N
N
D000293:Adolescent; D001528:Behcet Syndrome / Q000145:classification / Q000175:diagnosis* / Q000235:genetics*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009018:Morocco; D009679:Nuclear Family; D012189:Retrospective Studies