Prefabrication of bone by vascular induction: an experimental study in rabbits.
The various methods of prefabricating flaps include vascular induction through staged transfer; pretransfer delay, expansion, and grafting; the use of alloplastic materials; and tissue bioengineering. In this experimental study, vascular induction was used to provide an axial vascular pedicle to randomly nourished tissue. Twenty-six New Zealand rabbits, ages and weights ranging between 6 months-1 year and 1.5-3.5 kg, respectively, were used. The sex difference was not considered. The deep inferior epigastric artery and vein were used to carry blood and were placed into a segment of femur to prefabricate the bone. Four weeks later, the viability of the segment of bone prefabricated by new axial pedicle was shown by scintigraphic study, and the new axial pedicle was ready for free transfer.
Keser
Abdülmuttalip
A
Department of Plastic and Reconstructive Surgery, Emergency Care and Traumatology Hospital, Ankara, Turkey. nmbozkurt@yahoo.com
Bozkurt
Murat
M
Taner
Omer Faruk
OF
Akan
Mithat
M
Sensöz
Omer
O
D000818:Animals; D016025:Bone Transplantation / Q000379:methods; D001842:Bone and Bones / Q000098:blood supply*; D004195:Disease Models, Animal; D019074:Epigastric Arteries / Q000601:surgery*; D005260:Female; D006085:Graft Survival; D008297:Male; D008833:Microcirculation; D011817:Rabbits; D012039:Regional Blood Flow / Q000502:physiology; D012307:Risk Factors; D012680:Sensitivity and Specificity; D013524:Surgical Flaps / Q000098:blood supply*; D020858:Tissue and Organ Harvesting / Q000379:methods*