Amiodarone optic neuropathy--review.
The antiarrhythmic agent, amiodarone (Cordone), Pacerone), has been reported to cause optic neuropathy. However, the clinical manifestations are similar to non-arteritic anterior ischemic optic neuropathy (AION), which makes diagnosing amiodarone optic neuropathy difficult. There is controversy whether or not amiodarone optic neuropathy actually exists as a distinct entity. The clinical manifestations and the proposed pathophysiology of amiodarone optic neuropathy are discussed.
Chen
David
D
Ophthalmology, New England Medical Center, Tufts University, Boston, MA, USA. david8072@yahoo.com
Hedges
Thomas R
TR
D000638:Amiodarone / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D006801:Humans; D009901:Optic Nerve Diseases / Q000139:chemically induced* / Q000503:physiopathology / Q000628:therapy
D000889:Anti-Arrhythmia Agents; D000638:Amiodarone