title: Evidence for brain-derived neurotrophic factor-like neuropeptide in brain of the silk moth Bombyx mori during postembryonic periods.
abstract: Brain-derived neurotrophic factor-like neuropeptide is produced in the brain of the silk moth, Bombyx mori. Immunocytochemical studies of brain and retrocerebral complex of larvae, prepupae, pupae and adults showed that four pairs of median neurosecretory cells and six pairs of lateral neurosecretory cells which had different immunoreactivities to BDNF peptide. Day-1 adult brains showed no evidence of neurons stained by anti-BDNF antibodies. Those reactivities, which were much stronger in median cells than in lateral cells, were the weakest in an earliest larval stage and a latest pupal stage but the strongest in late larval stage. Median neurosecretory cells projected their axons into the contralateral corpora allata by decussation in the median region, nerve corpora cardiaca (NCC) I, and nerve corpora allata (NCA) I, whereas lateral neurosecretory cells extended their axons to the ipsilateral corpora allata via NCC II and NCA I.
authors.affiliation: School of Life Sciences and Biotechnology, Korea University, Anam-dong, Sungbuk-gu, Seoul 136-701, Korea.
authors.forename: Chan Woo
authors.initials: CW
authors.lastname: Park
authors.forename: Jin Hee
authors.initials: JH
authors.lastname: Kim
authors.forename: Kang Min
authors.initials: KM
authors.lastname: Kim
authors.forename: Jae Sam
authors.initials: JS
authors.lastname: Hwang
authors.forename: Seok Woo
authors.initials: SW
authors.lastname: Kang
authors.forename: Ho Suck
authors.initials: HS
authors.lastname: Kang
authors.forename: Byung Pil
authors.initials: BP
authors.lastname: Cho
authors.forename: Chai Hyeock
authors.initials: CH
authors.lastname: Yu
authors.forename: Hak Ryul
authors.initials: HR
authors.lastname: Kim
authors.forename: Bong Hee
authors.initials: BH
authors.lastname: Lee
mesh_terms: D000818:Animals; D012831:Bombyx / Q000254:growth & development*; D001923:Brain Chemistry; D019208:Brain-Derived Neurotrophic Factor / Q000235:genetics / Q000378:metabolism*; D003335:Corpora Allata / Q000166:cytology; D007150:Immunohistochemistry; D007814:Larva / Q000378:metabolism; D008675:Metamorphosis, Biological; D008954:Models, Biological; D009474:Neurons / Q000166:cytology / Q000378:metabolism; D009479:Neuropeptides / Q000235:genetics / Q000378:metabolism*; D011679:Pupa / Q000378:metabolism; D011994:Recombinant Proteins / Q000378:metabolism
chemical_list: D019208:Brain-Derived Neurotrophic Factor; D009479:Neuropeptides; D011994:Recombinant Proteins