Lactate dehydrogenase isoenzyme of lens in fetus.
OBJECTIVE
The LDH isoenzyme patterns were evaluated in lens of fetus to study the metabolism in human lenses.


METHODS
LDH isoenzyme electrophoresis was performed in 15 lenses of human fetus aged from 4 - 6 months.


RESULTS
There are 5 bands of LDH in fetus lens. LDH4 lever is the highest, and LDH1 is the lowest, especially in the cortex of lens. LDH1 is higher in lens of 4 months of age than in that of 5 and 6 months of age.


CONCLUSIONS
LDH isoenzyme in lens of fetus shows mainly anaerobic metabolism in development, but there is also aerobic metabolism, especially in younger fetus.
Ding
Kexi
K
Department of Ophthalmology, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Zhang
Yasong
Y
D004591:Electrophoresis, Polyacrylamide Gel; D005333:Fetus / Q000378:metabolism; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D007908:Lens, Crystalline / Q000201:enzymology*
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase