title: Plasmapheresis in the treatment of hyperthyroidism associated with agranulocytosis: A case report.
abstract: Plasmapheresis, also known as therapeutic plasma exchange, is used in the treatment of several disorders. Temporary improvement after plasmapheresis in cases with thyrotoxicosis has been reported. A 55-year-old woman presented with agranulocytosis induced by propylthiouracil and clinical signs of heart failure. Three sessions of plasmapheresis were performed. We observed an improvement of thyroid hormone levels and clinical findings as well. Plasmapheresis can be an option when drug treatment of thyrotoxicosis fails.
authors.affiliation: Division of Hematology, Cukurova University, Faculty of Medicine, Adana, Turkey. bguvenc@cu.edu.tr
authors.forename: Birol
authors.initials: B
authors.lastname: Guvenc
authors.forename: Cagatay
authors.initials: C
authors.lastname: Unsal
authors.forename: Emel
authors.initials: E
authors.lastname: Gurkan
authors.forename: Süleyman
authors.initials: S
authors.lastname: Dincer
mesh_terms: D000380:Agranulocytosis / Q000139:chemically induced*; D013956:Antithyroid Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000628:therapy*; D008875:Middle Aged; D010956:Plasmapheresis; D011441:Propylthiouracil / Q000009:adverse effects*
chemical_list: D013956:Antithyroid Agents; D011441:Propylthiouracil