title: A knowledgebase system to enhance scientific discovery: Telemakus.
abstract: BACKGROUND
  With the rapid expansion of scientific research, the ability to effectively find or integrate new domain knowledge in the sciences is proving increasingly difficult. Efforts to improve and speed up scientific discovery are being explored on a number of fronts. However, much of this work is based on traditional search and retrieval approaches and the bibliographic citation presentation format remains unchanged.
  
  
  METHODS
  Case study.
  
  
  RESULTS
  The Telemakus KnowledgeBase System provides flexible new tools for creating knowledgebases to facilitate retrieval and review of scientific research reports. In formalizing the representation of the research methods and results of scientific reports, Telemakus offers a potential strategy to enhance the scientific discovery process. While other research has demonstrated that aggregating and analyzing research findings across domains augments knowledge discovery, the Telemakus system is unique in combining document surrogates with interactive concept maps of linked relationships across groups of research reports.
  
  
  CONCLUSIONS
  Based on how scientists conduct research and read the literature, the Telemakus KnowledgeBase System brings together three innovations in analyzing, displaying and summarizing research reports across a domain: (1) research report schema, a document surrogate of extracted research methods and findings presented in a consistent and structured schema format which mimics the research process itself and provides a high-level surrogate to facilitate searching and rapid review of retrieved documents; (2) research findings, used to index the documents, allowing searchers to request, for example, research studies which have studied the relationship between neoplasms and vitamin E; and (3) visual exploration interface of linked relationships for interactive querying of research findings across the knowledgebase and graphical displays of what is known as well as, through gaps in the map, what is yet to be tested. The rationale and system architecture are described and plans for the future are discussed.
authors.affiliation: Telemakus Research Program, Division of Biomedical & Health Informatics, University of Washington, Seattle, WA, USA.
authors.forename: Sherrilynne S
authors.initials: SS
authors.lastname: Fuller
authors.affiliation: Telemakus Research Program, Division of Biomedical & Health Informatics, University of Washington, Seattle, WA, USA.
authors.forename: Debra
authors.initials: D
authors.lastname: Revere
authors.affiliation: Telemakus Research Program, Division of Biomedical & Health Informatics, University of Washington, Seattle, WA, USA.
authors.forename: Paul F
authors.initials: PF
authors.lastname: Bugni
authors.affiliation: Department of Pathology, School of Medicine, University of Washington, Seattle, WA, USA.
authors.forename: George M
authors.initials: GM
authors.lastname: Martin