Efficiency of refracterin in patients with chronic cardiac insufficiency caused by coronary heart disease.
Composite preparation refracterin administered in a dose of 300 mg/day for 3 days in addition to routine therapy significantly improved the results of treatment of severe cardiac insufficiency of ischemic genesis compared to placebo. Improvement of clinical status of patients is determined by positive dynamics of systolic and diastolic functions of the left ventricle.
Kanorskii
S G
SG
Krasnodar Research Center, Russian Academy of Medical Sciences, Administration of Krasnodar Krai; Krasnodar City Emergency Hospital.
Galenko-Yaroshevskii
P A
PA
Zingilevskii
K B
KB
D000113:Acetyldigoxins / Q000627:therapeutic use*; D000368:Aged; D002303:Cardiac Output, Low / Q000188:drug therapy* / Q000209:etiology; D002316:Cardiotonic Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D003327:Coronary Disease / Q000150:complications / Q000188:drug therapy*; D045304:Cytochromes c / Q000627:therapeutic use*; D004338:Drug Combinations; D004452:Echocardiography / Q000187:drug effects; D005260:Female; D006801:Humans; D007288:Inosine / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009243:NAD / Q000627:therapeutic use*; D010099:Oxyfedrine / Q000627:therapeutic use*; D013599:Systole / Q000187:drug effects; D016896:Treatment Outcome; D016277:Ventricular Function, Left / Q000187:drug effects
D000113:Acetyldigoxins; D002316:Cardiotonic Agents; D004338:Drug Combinations; D009243:NAD; D007288:Inosine; D045304:Cytochromes c; D010099:Oxyfedrine