Antimicrobial susceptibility patterns among viridans group streptococcal isolates from infective endocarditis patients from 1971 to 1986 and 1994 to 2002.
To determine whether changes in antimicrobial resistance have occurred among viridans group streptococci, we retrospectively examined 50 viridans group streptococcal isolates recovered from patients with infective endocarditis over 3 decades. Resistance rates (percent resistant isolates 1971 to 1986 and 1994 to 2002) were as follows: levofloxacin, 0 and 9; penicillin and clindamycin, 0 and 4; and erythromycin and azithromycin, 11 and 26, respectively.
Prabhu
Rajesh M
RM
Division of Infectious Diseases, Mayo Clinic College of Medicine, 200 First St. SW, Rochester, MN 55905, USA.
Piper
Kerryl E
KE
Baddour
Larry M
LM
Steckelberg
James M
JM
Wilson
Walter R
WR
Patel
Robin
R
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004697:Endocarditis, Bacterial / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D011159:Population Surveillance; D012189:Retrospective Studies; D020713:Vancomycin Resistance; D034363:Viridans Streptococci / Q000187:drug effects*
D000900:Anti-Bacterial Agents