title: Synthesis of the trisaccharide repeating unit of the atypical O-antigen polysaccharide from Danish Helicobacter pylori strains employing the 2'-carboxybenzyl glycoside.
abstract: [reaction: see text] Synthesis of the unique trisaccharide repeating unit of the O-polysaccharide of the lipopolysaccharide from Danish Helicobacter pylori strains has been accomplished. Key steps include the coupling of three monosaccharide moieties by glycosylations employing the 2'-carboxybenzyl glycoside method. Also presented is a method for the synthesis of the novel branched sugar, 3-C-methyl-D-mannose, which is one of three monosaccharide components.
authors.affiliation: Center for Bioactive Molecular Hybrids and Department of Chemistry, Yonsei University, Seoul 120-749, Korea.
authors.forename: Yong Tae
authors.initials: YT
authors.lastname: Kwon
authors.forename: Yong Joo
authors.initials: YJ
authors.lastname: Lee
authors.forename: Kyunghoon
authors.initials: K
authors.lastname: Lee
authors.forename: Kwan Soo
authors.initials: KS
authors.lastname: Kim
mesh_terms: D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D006027:Glycosides / Q000737:chemistry*; D006031:Glycosylation; D016480:Helicobacter pylori / Q000737:chemistry*; D008070:Lipopolysaccharides / Q000737:chemistry / Q000378:metabolism; D008766:Methylmannosides / Q000737:chemistry / Q000378:metabolism; D019081:O Antigens / Q000737:chemistry* / Q000378:metabolism; D011134:Polysaccharides / Q000737:chemistry*; D014312:Trisaccharides / Q000138:chemical synthesis*
chemical_list: D006027:Glycosides; D008070:Lipopolysaccharides; D008766:Methylmannosides; D019081:O Antigens; D011134:Polysaccharides; D014312:Trisaccharides