[Effect of qianlie huichun capsule on microstructure and ultranstructure of prostate glandular tissues in rats].
OBJECTIVE
To investigate the effect of Qianlie Huichun capsule on the microstructure and ultranstructure of prostate glandular tissue in the model rat.


METHODS
Hynertophy of prostate model rat was established by injecting testosterone to gelding male rats. After having been fed with Qianlie Huichun capsule for 30 days, the rats were killed and prostate tissues were resected for pathomorphological studies with microscope and electromicroscope, and the diameter of glandular lumer and the height of glandular epithelial cells were measured under the microspcope for different groups of rats.


RESULTS
In the model groups, the glandular epithelial cells mutiplycated notably, showing stratified and pseudostratified cells that made the glandular lumer cramped. Under the electromicroscope, the glandular epithelial cells became high columnor and the rough endoreticulum extremely expanded. But in treatment groups, the change of the diameter of the glandular lumer and the height of the glandular epithelial cells were less remarkable than those in model groups. So the differerence between the model group and the treatment groups was remarkable (P < 0.01).


CONCLUSIONS
Qianlie Huichun capsule can depress the glandular epithelialceu multiplication of prostate gland in model rats.
Duan
Deng-zhi
DZ
Traditional Medical and Medicine Institute of Yunnan, Kunming 650223, China.
Yu
Ling
L
Ten
Yi-shan
YS
Cheng
Li-ming
LM
Duan
Cheng-yu
CY
Yang
Yu-qi
YQ
Cao
Ji-gang
JG
D000818:Animals; D049109:Cell Proliferation / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D004847:Epithelial Cells / Q000473:pathology; D008297:Male; D008419:Materia Medica / Q000008:administration & dosage / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry; D011467:Prostate / Q000473:pathology* / Q000648:ultrastructure; D011470:Prostatic Hyperplasia / Q000139:chemically induced / Q000473:pathology*; D051381:Rats; D017207:Rats, Sprague-Dawley
D004365:Drugs, Chinese Herbal; D008419:Materia Medica