title: Small GTPases in vesicle trafficking.
abstract: Plant small GTPases belonging to the Rop, Arf, and Rab families are regulators of vesicle trafficking. Rop GTPases regulate actin dynamics and modulate H(2)O(2) production in polar cell growth and pathogen defence. A candidate Rop GDP to Rop GTP exchange factor (RopGEF) SPIKE1 is involved in the morphogenesis of leaf epidermal cells. The ArfGEF GNOM regulates the endosomal recycling of the PIN proteins, which are involved in polar auxin transport. Intracellular localisation of small GTPases and functional studies using dominant mutant versions of Arf and Rab GTPases are defining novel plant-specific membrane compartments, especially those that participate in endosomal vesicle trafficking.
authors.affiliation: Institut für Biologie II, Albert-Ludwigs-Universität Freiburg, Schänzlestrasse 1, 79104 Freiburg, Germany. arthur.molendijk@biologie.uni-freiburg.de
authors.forename: Arthur J
authors.initials: AJ
authors.lastname: Molendijk
authors.forename: Benedetto
authors.initials: B
authors.lastname: Ruperti
authors.forename: Klaus
authors.initials: K
authors.lastname: Palme
mesh_terms: D020727:ADP-Ribosylation Factors / Q000378:metabolism / Q000502:physiology; D001692:Biological Transport; D016764:Cell Polarity; D020558:GTP Phosphohydrolases / Q000378:metabolism / Q000502:physiology*; D007210:Indoleacetic Acids / Q000378:metabolism; D008954:Models, Biological; D010944:Plants / Q000276:immunology / Q000378:metabolism*; D015398:Signal Transduction; D020691:rab GTP-Binding Proteins / Q000378:metabolism / Q000502:physiology; D020741:rho GTP-Binding Proteins / Q000378:metabolism / Q000502:physiology
chemical_list: D007210:Indoleacetic Acids; D020558:GTP Phosphohydrolases; D020727:ADP-Ribosylation Factors; D020691:rab GTP-Binding Proteins; D020741:rho GTP-Binding Proteins