[Progress on the study of HLA-Cw--review].
HLA-Cw belongs to classic HLA-I gene, HLA-Cw molecules have high polymorphism like HLA-A and B molecules. They distribute extensively on the surfaces of karyote, not only presenting endogenetic antigen to CD8+ T cells to induce specific killing effect, but also participating in immunologic reaction as the ligands of killer cell immunoglobulin-like receptor (KIR). Thus it has been valued for their relations to diseases and the functions in transplantation immunity, anti virus and anti-tumor immunity.
Ma
Hong-Jing
HJ
Department of Hematology, Zhujiang Hospital, The First Military Medical University, Guangzhou 510282, China.
Xiao
Lu-Lu
LL
Guo
Kun-Yuan
KY
D001327:Autoimmune Diseases / Q000276:immunology; D006086:Graft vs Host Disease / Q000209:etiology; D015236:HLA-C Antigens / Q000235:genetics / Q000502:physiology*; D006801:Humans; D009369:Neoplasms / Q000276:immunology; D011971:Receptors, Immunologic / Q000378:metabolism; D054340:Receptors, KIR; D014777:Virus Diseases / Q000276:immunology
D015236:HLA-C Antigens; D011971:Receptors, Immunologic; D054340:Receptors, KIR