[Antibodies to beta-2 glycoprotein I in serum and aqueous humor of patients with glaucoma and their influence on the static perimetry].
OBJECTIVE
The evaluation of the relationships between the antibodies anti beta-2 glycoprotein I in serum and aqueous humor of the glaucoma patients to the visual field defects.


METHODS
48 persons (38 women and 17 men), aged 30-86 (mean age 70), suffering from glaucoma was examined. There were 19 with POAG, 18 with PACG and 11 with PEXG. All patients have undergone trabeculectomy. In plasma and anterior chamber fluid the level of antibodies to beta-2 glycoprotein I classes IgA and IgG were measured using ELISA method (commercial kits produced by Euroimmun), according to producer's instruction. The visual field defects were examined with Humphrey static perimetry. Statistical analysis was performed using Spearman test.


RESULTS
There were no significant correlations between antibodies anti beta-2 glycoprotein I, static perimetry, age and duration of the disease.


CONCLUSIONS
There have not been stated any relationships between the static perimetry to antiphospholipid antibodies level in serum and aqueous humor in patients with glaucoma. It is the preliminary communication.
Latalska
Małgorzata
M
II Kliniki Okulistyki Akademii Medycznej im. prof. Feliksa Skubiszewskiego w Lublinie.
Gerkowicz
Marek
M
Kosior-Jarecka
Ewa
E
Kozioł-Montewka
Maria
M
Pietraś-Trzpiel
Małgorzata
M
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001082:Aqueous Humor / Q000276:immunology*; D001323:Autoantibodies / Q000097:blood / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005901:Glaucoma / Q000276:immunology* / Q000503:physiopathology* / Q000601:surgery; D006023:Glycoproteins / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D014130:Trabeculectomy; D058609:Visual Field Tests; D014794:Visual Fields / Q000276:immunology; D053482:beta 2-Glycoprotein I
D001323:Autoantibodies; D006023:Glycoproteins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D053482:beta 2-Glycoprotein I