title: Bone remodelling of a proximal femur with the thrust plate prosthesis: an in vitro case.
abstract: The key to the development of a successful implant is an understanding of the effect of bone remodelling on its long-term fixation. In this study, clinically observed patterns of bone remodelling have been compared with computer-based predictions for one particular design of prosthesis, the Thrust Plate Prosthesis (Centerpulse Orthopedics, Winterthur, Switzerland). Three-dimensional finite-element models were created using geometrical and bone density data obtained from CT scanning. Results from the bone remodelling simulation indicated that varying the relative rate of bone deposition/resorption and the interfacial conditions between the bone and the implant could produce the trend towards the two clinically observed patterns of remodelling.
authors.affiliation: Department of Mechanical Engineering, University of Bath, Claverton Down, BA2 7AY Bath, UK.
authors.forename: W R
authors.initials: WR
authors.lastname: Taylor
authors.forename: H
authors.initials: H
authors.lastname: Ploeg
authors.forename: D
authors.initials: D
authors.lastname: Hertig
authors.forename: M D
authors.initials: MD
authors.lastname: Warner
authors.forename: S E
authors.initials: SE
authors.lastname: Clift
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects / Q000379:methods; D001860:Bone Plates; D016723:Bone Remodeling / Q000502:physiology*; D001862:Bone Resorption / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D003198:Computer Simulation; D003936:Diagnosis, Computer-Assisted / Q000379:methods; D019544:Equipment Failure Analysis / Q000379:methods*; D005269:Femur / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery*; D020342:Finite Element Analysis; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D006622:Hip Prosthesis; D006801:Humans; D008954:Models, Biological; D011475:Prosthesis Failure; D011859:Radiography; D013314:Stress, Mechanical; D016474:Weight-Bearing