title: Lipid function in plant cell polarity.
abstract: The establishment and maintenance of cell polarity play pivotal roles during plant development. During the past five years, proteins that are required for different aspects of plant cell polarity have been identified. However, the functions of lipids and their interactions with proteins that mediate polarity remained largely unaddressed. Recent genetic studies have discovered cell and tissue polarity mutants that have defects in sterol composition, glycosylphosphatidylinositol-anchored proteins, glycosylphosphatidylinositol biosynthesis and phospholipid signalling. Analyses of the affected gene products have provided a first glance at the roles of lipids in cell polarity signalling, as well as in the trafficking and anchoring of polar proteins.
authors.affiliation: Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, 90183 Umeå, Sweden.
authors.forename: Urs
authors.initials: U
authors.lastname: Fischer
authors.forename: Shuzhen
authors.initials: S
authors.lastname: Men
authors.forename: Markus
authors.initials: M
authors.lastname: Grebe
mesh_terms: D017360:Arabidopsis / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D016764:Cell Polarity; D035264:Flowers / Q000254:growth & development; D017261:Glycosylphosphatidylinositols / Q000378:metabolism; D050356:Lipid Metabolism; D008055:Lipids / Q000502:physiology*; D010940:Plant Proteins / Q000378:metabolism; D018517:Plant Roots / Q000254:growth & development; D015398:Signal Transduction; D013261:Sterols / Q000378:metabolism
chemical_list: D017261:Glycosylphosphatidylinositols; D008055:Lipids; D010940:Plant Proteins; D013261:Sterols