Highly stereo- and regioselective ni-catalyzed homoallylation of aldimines with conjugated dienes promoted by diethylzinc.
Under the nickel catalysis, in one pot, diethylzinc serves as a reducing agent to connect the three components of 1,3-dienes, alkyl or aryl aldehydes, and anilines to furnish 3-substituted 3,5-syn-5-(arylamino)pent-1-enes 1, the homoallylation products of aldimines with dienes, in excellent yields and with high regio- and stereoselectivity.
Kimura
Masanari
M
Department of Applied Chemistry, Faculty of Engineering, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Miyachi
Atsuko
A
Kojima
Keisuke
K
Tanaka
Shuji
S
Tamaru
Yoshinao
Y