title: [Study on preparation of beta-cyclodextrin inclusion complex of volatile oil in xiongdan xiaoyan capsules].
abstract: OBJECTIVE
  To study optimum inclusion conditions for volatile oil from three medicinal slices in Xiongdan Xiaoyan capsules.
  
  
  METHODS
  Saturated water solution method (agitation method), ultrasonic method and rubbing method were studied and compared. The preparation conditions of ultrasonic method were investigated by the orthogonal test.
  
  
  RESULTS
  The optimum inclusion conditions of ultrasonic method were established.
  
  
  CONCLUSIONS
  The ultrasonic method can be used for production of inclusion complex in the factory with high inclusion rate and was effectiveness.
authors.affiliation: Laboratory of Targeting and New Drug Delivery Systems, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
authors.forename: Xiong-liang
authors.initials: XL
authors.lastname: Xu
authors.forename: Zhi-rong
authors.initials: ZR
authors.lastname: Zhang
authors.forename: Zu-xing
authors.initials: ZX
authors.lastname: He
authors.forename: Guo-qing
authors.initials: GQ
authors.lastname: Huang
authors.forename: Dong
authors.initials: D
authors.lastname: Ran
mesh_terms: D029969:Angelica / Q000737:chemistry; D002214:Capsules; D004337:Drug Carriers; D004338:Drug Combinations; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000302:isolation & purification; D027541:Mentha / Q000737:chemistry; D009822:Oils, Volatile / Q000008:administration & dosage* / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry*; D032134:Saururaceae / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*; D014465:Ultrasonics; D047392:beta-Cyclodextrins
chemical_list: D002214:Capsules; D004337:Drug Carriers; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D009822:Oils, Volatile; D047392:beta-Cyclodextrins; C031215:betadex