Review of "Implications of Hormesis for Industrial Hygiene".
Hormesis is an appealing concept when considered from the evolutionary viewpoint. It may provide a new approach to deriving the "no observed adverse effect level" for occupational exposures to chemicals. An over-reliance on mathematical modeling without a clear understanding of exposures and health outcomes stymies current scientific decision-making. Care must be taken, however, as not all endpoints will exhibit a hormetic response.
Brosseau
L M
LM
School of Public Health, Universityof Minnesota, Minneapolis, USA. brosseau@umn.edu
D000818:Animals; D004305:Dose-Response Relationship, Drug; D006801:Humans; D019055:No-Observed-Adverse-Effect Level; D016273:Occupational Exposure; D016272:Occupational Health; D018675:Toxicity Tests / Q000379:methods