title: Tandem oxidation processes for the preparation of functionalized cyclopropanes.
abstract: [reaction: see text] A novel manganese dioxide-mediated tandem oxidation process (TOP) has been developed which allows the direct conversion of allylic alcohols into cyclopropanes, the intermediate aldehydes being trapped in situ with a stabilized sulfur-ylide. This methodology has been applied successfully to a variety of allylic alcohols and to a formal synthesis of the simple, naturally occurring lignan, (+/-)-picropodophyllone.
authors.affiliation: Department of Chemistry, University of York, Heslington, York YO10 5DD, UK.
authors.forename: Magalie F
authors.initials: MF
authors.lastname: Oswald
authors.forename: Steven A
authors.initials: SA
authors.lastname: Raw
authors.forename: Richard J K
authors.initials: RJ
authors.lastname: Taylor