title: High-resolution imaging of living retina through optic adaptive retinal imaging system.
abstract: OBJECTIVE
  To evaluate the possibility as well as the usage of adaptive optics in high-resolution retinal imaging.
  
  
  METHODS
  From March to November 2001, the fundus of 25 adults were checked by using Optic Adaptive Retinal Imaging System (OAS). The age of the subjects varied from 18 - 48 years. All had normal visual acuity from 0.9 to 1.0. No abnormality was found in the ocular examination, and their medical as well as ocular history was unremarkable.
  
  
  RESULTS
  High-resolution images of the retinal cells, photoreceptor and bipolar cell, were analysed. In these images, the cells are clearly resolved. The density of the photoreceptor at area 1.5 degree from the foveloa is around 40 000 - 50 000/mm2. At area 3 degree, it drops to less than 30 000/mm2.
  
  
  CONCLUSIONS
  Optic Adaptive Retinal Imaging System (AOS) is able to get high-resolution image of retinal cells in living human eyes. It may be widely used in ophthalmology experimentally and clinically.
authors.affiliation: Eye ENT Hospital of Fudan University, Shanghai 200031, China.
authors.forename: Chunhui
authors.initials: C
authors.lastname: Jiang
authors.forename: Wenji
authors.initials: W
authors.lastname: Wang
authors.forename: Ning
authors.initials: N
authors.lastname: Ling
authors.forename: Gezhi
authors.initials: G
authors.lastname: Xu
authors.forename: Xuejun
authors.initials: X
authors.lastname: Rao
authors.forename: Xinyang
authors.initials: X
authors.lastname: Li
authors.forename: Yudong
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D015350:Contrast Sensitivity / Q000502:physiology; D003941:Diagnostic Techniques, Ophthalmological; D005654:Fundus Oculi; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D007368:Interferometry / Q000295:instrumentation / Q000379:methods*; D008875:Middle Aged; D009887:Ophthalmoscopy / Q000379:methods; D055095:Optics and Photonics / Q000295:instrumentation*; D012160:Retina / Q000033:anatomy & histology* / Q000502:physiology; D014785:Vision, Ocular