Distal arthrogryposis and neonatal hypotonia: an unusual presentation of Prader-Willi syndrome (PWS).
The clinical features of Prader-Willi Syndrome (PWS) in the neonate are marked by hypotonia, absence of crying, and feeding difficulties, but the clinical nature of PWS in utero remains unclear. We report a case of PWS with fetal immobility and distal arthrogryposis in a girl admitted the first day of life to the neonatal intensive care unit for severe hypotonia and respiratory distress.
Denizot
S
S
Département de périnatologie, CHU de Nantes, France.
Boscher
C
C
Le Vaillant
C
C
Rozé
J C
JC
Gras Le Guen
C
C
D001176:Arthrogryposis / Q000150:complications*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009123:Muscle Hypotonia / Q000150:complications*; D011218:Prader-Willi Syndrome / Q000150:complications / Q000175:diagnosis*