title: Helicobacter pylori: recombination, population structure and human migrations.
abstract: Helicobacter pylori shows extensive genetic diversity and variability due to frequent intraspecific recombination during mixed infection. In the last years, modern genetic and genomic technology as well as cutting-edge population genetic analysis have been used to investigate the population structure and genetic variability of this pathogen. This review article summarizes recent developments in this rapidly moving field.
authors.affiliation: Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Medizinische Hochschule Hannover, Carl-Neuberg-Str 1, D-30625 Hannover, Germany. suerbaum.sebastian@mh-hannover.de
authors.forename: Sebastian
authors.initials: S
authors.lastname: Suerbaum
authors.forename: Mark
authors.initials: M
authors.lastname: Achtman
mesh_terms: D017753:Ecosystem; D004641:Emigration and Immigration; D014644:Genetic Variation; D016680:Genome, Bacterial; D016481:Helicobacter Infections / Q000453:epidemiology* / Q000382:microbiology*; D016480:Helicobacter pylori / Q000235:genetics* / Q000472:pathogenicity*; D006801:Humans; D017720:Molecular Epidemiology; D011157:Population Dynamics; D011995:Recombination, Genetic