title: [Chronic necrotizing pulmonary aspergillosis in an immunocompromised patient].
abstract: A case with chronic necrotizing pulmonary aspergillosis that was mimicking the radiomorphology of malignant tumor was reported. The patient was admitted to hospital with progression of a left upper lobe infiltrate which was known and under regular observation for 8 years, and haemoptoe. Computer tomography scan showed a spiculated abnormality in the left upper lobe with mediastinal lymphadenomegaly. Based on this finding pulmonary malignancy was suspected and, therefore, the patient was referred to surgical intervention. The post surgical histology revealed aspergillus in the specimen. Since signs of vascular invasion could not be detected microscopically and the disease developed in immunocompromised patient (due to diabetes mellitus and long term steroid treatment) the clinical condition was determined as chronic necrotizing aspergillosis. It is very likely that the pathogen infected the patient during his daily work in a bakery. The present paper also summarizes the clinical aspects, differential diagnosis and therapy of different forms of pulmonary aspergillosis with emphasis on chronic necrotizing pulmonary aspergillosis.
authors.affiliation: Semmelweis Egyetem, Altalános Orvostudományi Kar, Pulmonológiai Klinika, Budapest.
authors.forename: Anikó
authors.initials: A
authors.lastname: Bohács
authors.forename: Judit
authors.initials: J
authors.lastname: Kocsis
authors.forename: Akos
authors.initials: A
authors.lastname: Somoskövi
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Mészáros
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Sápi
authors.forename: Lilla
authors.initials: L
authors.lastname: Tamási
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Bártfai
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000009:adverse effects; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy; D002908:Chronic Disease; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D003937:Diagnosis, Differential; D006801:Humans; D016867:Immunocompromised Host; D008172:Lung Diseases, Fungal / Q000145:classification / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects; D011379:Prognosis; D012307:Risk Factors
chemical_list: D000305:Adrenal Cortex Hormones; D000935:Antifungal Agents