title: Stereoselective synthesis and antifungal activity of (Z)-trans-3-azolyl-2-methylchromanone oxime ethers.
abstract: A series of (Z)-trans-3-azolyl-2-methylchromanone oxime ethers were stereoselectively synthesized and tested for in vitro antifungal activity. Many of these derivatives exhibit high activity against Candida albicans, Saccharomyces cerevisiae, Aspergillus niger, and Microsporum gypseum.
authors.affiliation: Department of Medicinal Chemistry, Faculty of Pharmacy, Mazandaran University of Medical Sciences, PO Box 48175-861 Sari, Iran.
authors.forename: Saeed
authors.initials: S
authors.lastname: Emami
authors.forename: Mehraban
authors.initials: M
authors.lastname: Falahati
authors.forename: Ali
authors.initials: A
authors.lastname: Banifatemi
authors.forename: Abbas
authors.initials: A
authors.lastname: Shafiee
mesh_terms: D000880:Anthraquinones / Q000138:chemical synthesis* / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects / Q000254:growth & development; D002867:Chromones; D008826:Microbial Sensitivity Tests / Q000706:statistics & numerical data; D010091:Oximes / Q000138:chemical synthesis* / Q000494:pharmacology; D013237:Stereoisomerism
chemical_list: D000880:Anthraquinones; D000935:Antifungal Agents; D002867:Chromones; D010091:Oximes; C469373:chaetomanone