title: [Lazarus phenomenon: spontaneous resuscitation].
abstract: A 94-year-old woman undergoing surgery for simple repair of a duodenal perforation experienced a sudden massive hemorrhage (1500 mL) when the duodenum was separated from adjacent structures. Hemodynamic stability was re-established when fluids were replaced. After the abdominal wall was closed, increased amplitude of the QRS wave was observed and heart rate slowed until there was no pulse. Electromechanical dissociation (EMD) was diagnosed and cardiopulmonary resuscitation was started. When EMD persisted after 40 minutes, resuscitative measures were stopped and the ventilator was disconnected, though orotracheal intubation and arterial and electrocardiographic monitoring were maintained. After 2 or 3 minutes, heart rhythm restarted spontaneously and arterial pressure waves reappeared on the monitor. The patient progressed well for 72 hours, after which she developed septic shock and multiorgan failure, dying 18 days later. The Lazarus phenomenon may be more common than the medical literature would indicate, possibly because a large gap in our understanding of the pathophysiology of the phenomenon underlies anecdotes about "miracles". As we wait for adequate international consensus on a protocol for monitoring the withdrawal of resuscitative measures, we should act prudently before definitively certifying death. The case we report occurred during a surgical intervention in which the patient had received general anesthesia. We believe that the causes that might explain the Lazarus phenomenon are quite different in that context than they would be in a nonsurgical setting, such that it would be useful to create a national database to keep a record of such intraoperative events.
authors.affiliation: Departamento de Anestesiología y Reanimación, Hospital Universitario Virgen Macarena, Sevilla. jlcasielles@hotmail.com
authors.forename: J L
authors.initials: JL
authors.lastname: Casielles García
authors.forename: M V
authors.initials: MV
authors.lastname: González Latorre
authors.forename: N
authors.initials: N
authors.lastname: Fernández Amigo
authors.forename: A
authors.initials: A
authors.lastname: Guerra Vélz
authors.forename: M
authors.initials: M
authors.lastname: Cotta Galán
authors.forename: E
authors.initials: E
authors.lastname: Bravo Capaz
authors.forename: M
authors.initials: M
authors.lastname: de las Mulas Béjar
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006323:Heart Arrest; D006801:Humans; D012075:Remission, Spontaneous