[Spinal anesthesia with isobaric 0.5% bupivacaine for lower limb surgery: effects of different volumes].
BACKGROUND
The effects of different volumes (2.4, 2.6, 2.8 and 3.0 ml) of isobaric 0.5% bupivacaine used for spinal anesthesia were compared in 206 patients scheduled for lower limb surgery.


METHODS
The spinal anesthesia was performed with the patients in the lateral position and the isobaric 0.5% bupivacaine was injected intrathecally at the L3-4 interspace.


RESULTS
The time to maximum cephalad spread of anesthesia (loss of cold sensation) varied between 25 and 40 min. A significant difference was found in cephalad spread between 2.4 ml group and 3.0 ml group (T11 vs T7), and between 2.6 ml group and 3.0 ml group (T11 vs T7). Severe hypotension did not occur during the study.


CONCLUSIONS
Spinal anesthesia with 2.8 ml of isobaric 0.5% bupivacaine proved satisfactory for lower limb surgery.
Haranishi
Yasunori
Y
Department of Anesthesia, Yamaguchi Prefectural Central Hospital, Hofu 747-8511.
Matayoshi
Yasutoshi
Y
Yoshitomi
Kaori
K
Uchida
Masato
M
Nakamura
Kumiko
K
Oka
Hideo
H
Tamura
Hisashi
H
Shibasaki
Seiichi
S
D000328:Adult; D000368:Aged; D000775:Anesthesia, Spinal; D000779:Anesthetics, Local / Q000008:administration & dosage* / Q000493:pharmacokinetics; D002045:Bupivacaine / Q000008:administration & dosage* / Q000493:pharmacokinetics; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007278:Injections, Spinal; D035002:Lower Extremity / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012996:Solutions; D013997:Time Factors
D000779:Anesthetics, Local; D012996:Solutions; D002045:Bupivacaine