title: An efficient multi-stage, single-arm Phase II futility design for ALS.
authors.affiliation: Medical University of South Carolina, Charleston, SC, USA.
authors.forename: Yuko Y
authors.initials: YY
authors.lastname: Palesch
authors.forename: Barbara C
authors.initials: BC
authors.lastname: Tilley
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000188:drug therapy*; D017322:Clinical Trials, Phase II as Topic / Q000379:methods*; D006801:Humans; D012107:Research Design / Q000639:trends*