Osteopenia and osteoporosis in HIV+ patients, untreated or receiving HAART.
In the last few years there are increasing evidences suggesting that osteopenia and osteoporosis are frequent among HIV positive patients. It is still not clear if the bone demineralization is a direct consequence of viral infection or of the antiretroviral drugs. Studies to date therefore give conflicting results. We performed a study to evaluate the prevalence of osteopenia and osteoporosis in HIV positive patients, either untreated or receiving antiretroviral therapy, to asses the frequency of these conditions and the role of antiretroviral drugs.
Landonio
S
S
1st Department of Infectious Diseases and Allergy, Luigi Sacco Hospital, Via GB Grassi 74, 20157 Milan, Italy.
Quirino
T
T
Bonfanti
P
P
Gabris
A
A
Boccassini
L
L
Gulisano
C
C
Vulpio
L
L
Ricci
E
E
Carrabba
M
M
Vigevani
G M
GM
D000328:Adult; D000704:Analysis of Variance; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D015519:Bone Density / Q000187:drug effects / Q000502:physiology; D001851:Bone Diseases, Metabolic / Q000139:chemically induced / Q000000981:diagnostic imaging* / Q000453:epidemiology; D016009:Chi-Square Distribution; D005260:Female; D015658:HIV Infections / Q000000981:diagnostic imaging* / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000453:epidemiology; D014463:Ultrasonography