[Changes of axoplasmic transportation during experimental facial nerve regeneration].
OBJECTIVE
To determine the roles of axoplasmic transportation during regeneration after facial nerve injury.


METHODS
Facial nucleus injection and isotopic-label tracer with liquid scintillation counting techniques were used to investigate the changes of radioactivity after guinea pig facial nerve compressed.


RESULTS
Axoplasmic transportation was observed again at 3 d after facial nerve injury, and the function recovered until 14 d. At 21 d after injury, it showed that transportation curve of radiolabeled protein was similar with that of the normal. There was particular curve in slow axoplasmic transportation that included two wave: W1 and W2. The axons regenerated at a rate of (2.84 +/- 0.12) mm/d in fast transportation while that of slow transportation is (3.16 +/- 0.08) mm/d.


CONCLUSIONS
It suggests that axoplasmic transport act as a important role during the course of facial nerve regeneration.
Ma
Hongmin
H
Department of Otorhinolaryngology, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032.
Wang
Jinling
J
Qiu
Jianhua
J
Huang
Weiguo
W
D000818:Animals; D001370:Axonal Transport / Q000502:physiology*; D020220:Facial Nerve Injuries / Q000378:metabolism*; D005260:Female; D006168:Guinea Pigs; D008297:Male; D009416:Nerve Regeneration