[An epidemiological study on omphalocele in China during 1996 to 2000].
OBJECTIVE
To understand the trend of incidence of omphalocele and its epidemiological characteristics in China during 1996 to 2000.


METHODS
Surveillance data of omphalocele were collected from 460 hospitals at county level or above county level, involving all births with 28-week gestation to 7 days after delivery, including live births, fetal deaths and stillbirths in 31 provinces, autonomous regions and municipalities all over the country during 1996 to 2000.


RESULTS
Overall incidence of omphalocele in China was 1.52 per 10 000 live births, with an increasing trend during 1996 to 2000. Incidence of omphalocele was 1.40 per 10 000 and 1.83 per 10 000 in the rural and urban areas, respectively, with a statistically significant difference (P < 0.05), and 1.54 per 10 000 and 1.41 per 10 000 in boys and girls, respectively. Babies of omphalocele associated with other malformation accounted for 30.77% of the total cases. Perinatal fatality rate of omphalocele was 51.18%, with prenatal diagnostic rate of 31.07%.


CONCLUSIONS
Prevalence of omphalocele appeared an increasing trend in China during the period from 1996 to 2000. Occurrence of omphalocele was more frequent in rural areas than that in urban areas. Perinatal fatality rate in babies with omphalocele was higher and fatality of associated omphalocele was higher than that of simple one. It is suggested that management of perinatal care and level of prenatal diagnosis for omphalocele should be improved.
Zhou
Guang-Xuan
GX
National Center for Birth Defects Monitoring, The Second West China Hospital, Sichuan University, Chengdu 610041, China.
Liang
Juan
J
Zhu
Jun
J
Dai
Li
L
Wang
Yan-Ping
YP
Miao
Lei
L
D002681:China / Q000453:epidemiology; D005260:Female; D006554:Hernia, Umbilical / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008297:Male; D012423:Rural Health