[Sentinel node study with patent blue in cervical cancer].
OBJECTIVE
The purpose of this study was to determine the feasibility of sentinel node identification in patients with invasive cervix cancer undergoing radical hysterectomy and pelvic lymphadenectomy using intraoperative lymphatic mapping with patent blue dye.


METHODS
Fifty one patients wtih Figo I and II cervical cancer were submitted to radical hysterectomy and pelvic lymphadenectomy. The patent blue V was injected around the tumor before beginning surgery. At the time of pelvic lymphadenectomy, lymph nodes with obvious uptake of the dye were separated from the remainder of the lymphadenectomy specimen.


RESULTS
Sentinel nodes were detected in 32 of the 51 patients. Four cases of false negative were observed. The specificity, sensitivity, positive predictive value and negative predictive value were 38.6%, 42.8%, 10% and 80.9%, respectively.


CONCLUSIONS
Identification of sentinel node with patent blue dye is feasible in cervical cancer. A larger series will be required to establish sentinel detection in cervical cancer for further therapy concepts and planning.
Vieira
Sabas Carlos
SC
Departamento de Clínica Geral, Universidade Federal do Piauí e Hospital São Marcos, Teresina, PI. sabasmarcia@uol.com.br
Zeferino
Luiz Carlos
LC
Silva
Benedito Borges da
BB
Santana
Jerúsia O Ibiapina de
JO
Santos
Lina Gomes dos
LG
Carvalho
Teresinha Castello Branco
TC
Rocha
Maria Castelo Branco de Deus
MC
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000556:secondary; D004396:Coloring Agents; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology* / Q000601:surgery; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009367:Neoplasm Staging; D010388:Pelvis; D012394:Rosaniline Dyes; D012680:Sensitivity and Specificity; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis*
D004396:Coloring Agents; D012394:Rosaniline Dyes; C008769:sulfan blue