Balanced de novo translocation t(6;7)(p25;q31) and cleft palate as an isolated finding.
We report a prenatally diagnosed balanced de novo translocation t(6;7)(p25;q31). Physical examination of the baby born at term revealed only a posterior cleft palate. Laboratory examinations and radiologic investigations were found normal. Two years follow-up of the patient showed her mental and motor development was appropriate with her age. Our report is the first observation on balanced de novo translocation t(6;7)(p25;q31) and cleft palate. Association of this translocation and cleft palate has not been reported previously.
Balci
S
S
Department of Clinical Genetics, Hacettepe University, Ihsan Doğramaci Children's Hospital, 06100 Sihhiye, Ankara, Turkey. sbalci@hacettepe.edu.tr
Aypar
E
E
Son
Y Aydin
YA
Beksaç
M S
MS
D000328:Adult; D002896:Chromosomes, Human, Pair 6 / Q000235:genetics*; D002897:Chromosomes, Human, Pair 7 / Q000235:genetics*; D002899:Chromosomes, Human, Pair 9 / Q000235:genetics*; D002972:Cleft Palate / Q000175:diagnosis / Q000235:genetics*; D005260:Female; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014178:Translocation, Genetic