Controversies in surgical pathology: minimal involvement of sentinel lymph node in breast carcinoma: prevailing concepts and challenging problems.
Sentinel lymph node biopsy has attained "standard of care'' status in the management of breast carcinoma. However, the pathological interpretation and clinical consequences of "minimally involved'' sentinel lymph nodes remain controversial. Herein, we present some of the complex and challenging pathological problems inherent in this evolving setting. Clearly, at least some of our current concepts regarding "minimally involved'' sentinel lymph nodes need reappraisal.
Rivera
Michael
M
Department of Pathology, New York Presbyterian Hospital-Weill Cornell Medical Center and Weill Medical College of Cornell University, New York, NY, USA.
Merlin
Scott
S
Hoda
Rana S
RS
Gopalan
Anuradha
A
Hoda
Syed A
SA
D000328:Adult; D000368:Aged; D001365:Axilla; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D002277:Carcinoma / Q000556:secondary* / Q000601:surgery; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D010340:Pathology, Surgical / Q000379:methods* / Q000592:standards; D021701:Sentinel Lymph Node Biopsy