title: Comparative study of plateletpheresis using Baxter CS 3000 plus and Haemonetics MCS 3P.
abstract: Platelet concentrates made from cell separators are used more frequently due to less donor exposure and leucodepletion. This retrospective study was done to compare plateletpheresis done on two cell separators: Baxter CS 3000 plus and Haemonetics MCS 3p. Plateletpheresis procedures, done from January 1997 to April 2002, were included in the study. One hundred and seven procedures were done on Haemonetics MCS 3p using SDP protocol, 49 procedures were done on Haemonetics MCS 3p using PLP protocol, and 107 were done on Baxter CS 3000 plus. Pre-procedure donor's platelet count and haemoglobin were comparable in all the groups. Platelet yield was comparable in PLP (6.44 x 10(11) platelets) and SDP (5.27 x 10(11)) protocols, but significantly less in Baxter (4.05 x 10(11) platelets, P < 0.001 for PLP and P < 0.05 for SDP). Efficiency of platelet removal was statistically significantly different in all the groups (P < 0.0001), however it was more in PLP (PLP-55.02%, SDP-47.38%, Baxter 38.98%). A significant number of products (19.51%) of Baxter failed to comply platelet count of product < or = 2,435 x 10(9)/l compared to 5.13% in PLP and 1.23% in SDP group; 36.96% of units from PLP and 28% from SDP qualified for split products compared to 1.18% of Baxter. PLP protocol of Haemonetics MCS 3p gives better platelet yield compared to Baxter CS 3000 plus and SDP protocol of Haemonetics MCS 3p.
authors.affiliation: Green Cross Apheresis and Genetic Research Centre, 222 Anil Kunj, Paldi Char Rasta, Ahmedabad-380006, India. jagash@wilnetonline.net
authors.forename: Ashwin P
authors.initials: AP
authors.lastname: Patel
authors.forename: Amarjit
authors.initials: A
authors.lastname: Kaur
authors.forename: Vinod
authors.initials: V
authors.lastname: Patel
authors.forename: Narendra
authors.initials: N
authors.lastname: Patel
authors.forename: Dilip
authors.initials: D
authors.lastname: Shah
authors.forename: Sunil
authors.initials: S
authors.lastname: Kanvinde
authors.forename: Sanjay
authors.initials: S
authors.lastname: Prajapati
authors.forename: Hiral
authors.initials: H
authors.lastname: Patel
authors.forename: Dinesh
authors.initials: D
authors.lastname: Rathod
authors.forename: Rashmin
authors.initials: R
authors.lastname: Adesara
authors.forename: Shubha
authors.initials: S
authors.lastname: Rani
mesh_terms: D001810:Blood Volume; D005260:Female; D006801:Humans; D008297:Male; D010976:Platelet Count; D010983:Plateletpheresis / Q000295:instrumentation*; D012189:Retrospective Studies