Allylsilanes and vinylsilanes from silylcupration of carbon-carbon multiple bonds: scope and synthetic applications.
Silylcupration of multiple bonds (allenes, acetylenes, dienes, and styrenes) has become one of the most efficient procedures for the synthesis of vinyl- and allylsilanes. These substrates are useful building blocks in organic synthesis since they undergo a great variety of silicon-assisted transformations. The methodology reported has been widely used in the synthesis of different natural products, as well as in the construction of carbo- and heterocycles. In this Account, we wish to illustrate our contribution to this field, as well as to highlight the contributions of others.
Barbero
Asunción
A
Departamento de Química Orgánica, Facultad de Ciencias, C/ Dr Mergelina s/n, 47011 Valladolid, Spain.
Pulido
Francisco J
FJ