title: [Gastroesophagopharyngeal reflux in infants and children with recurrent symptoms of the upper respiratory tract].
abstract: Gastroesophageal reflux (GER) plays an important role in pathogenesis of recurrent/chronic disorders of the respiratory tract. Atypical symptoms of GER can be suggested to be cause of the otorhinolaryngological problems. For these last manifestations no cause-effect relationship has yet been proven. There are many therapeutic studies, in which treatment of GERD is examined for its impact on coexisting respiratory disorders. The aim of our study was to confirm the presence of acid reflux by using 24-hour intraesophageal pH monitoring. From the group of 29 patients with recurrent episodes of the pharyngitis, laryngitis and tracheitis, we evaluated 18 children aged 3 months to 8 years (mean, 4.23 +/- 2.85) with coexisting reflux symptoms. The protocol included a parenteral interview, physical examination, roentgenograms of the chest and larynx, laryngoscopy, as well as 24-hour simultaneous proximal and distal esophageal pH monitoring. The most significant differences between examined patients and control subjects was noted in terms of the lowest pH value, number of reflux episodes and index reflux while pH dropped below 4. Every significant drop under pH 6 recorded in proximal esophagus was simultaneous with reflux episode in distal esophagus. We found increased both sensitivity and specificity of the simultaneous pH monitoring in the distal and proximal part of the esophagus comparing to monitoring by the single probe. We confirmed the presence of gastroesophagopharyngeal reflux in patients with recurrent disorders of pharynx, larynx and/or trachea.
authors.affiliation: III Klinika Chorób Dzieci Akademii Medycznej w Białymstoku.
authors.forename: Janusz
authors.initials: J
authors.lastname: Semeniuk
authors.forename: Maciej
authors.initials: M
authors.lastname: Kaczmarski
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Sidor
authors.forename: Aleksander
authors.initials: A
authors.lastname: Krasnow
authors.forename: Urszula
authors.initials: U
authors.lastname: Daniluk
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Matuszewska
mesh_terms: D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D007827:Laryngitis / Q000209:etiology*; D008297:Male; D008991:Monitoring, Physiologic; D010612:Pharyngitis / Q000209:etiology*; D011044:Poland; D012008:Recurrence; D012680:Sensitivity and Specificity; D013997:Time Factors; D014136:Tracheitis / Q000209:etiology*