The ser9gly SNP in the dopamine D3 receptor causes a shift from cAMP related to PGE2 related signal transduction mechanisms in transfected CHO cells.
Hellstrand
M
M
Danielsen
E A
EA
Steen
V M
VM
Ekman
A
A
Eriksson
E
E
Nilsson
C L
CL
D019943:Amino Acid Substitution; D000818:Animals; D016466:CHO Cells; D006224:Cricetinae; D003412:Cricetulus; D000242:Cyclic AMP / Q000378:metabolism*; D015232:Dinoprostone / Q000096:biosynthesis* / Q000378:metabolism; D004298:Dopamine / Q000494:pharmacology; D005998:Glycine / Q000235:genetics; D006801:Humans; D020641:Polymorphism, Single Nucleotide; D017448:Receptors, Dopamine D2 / Q000235:genetics* / Q000378:metabolism; D050637:Receptors, Dopamine D3; D012694:Serine / Q000235:genetics; D015398:Signal Transduction; D014162:Transfection
C493593:DRD3 protein, human; D017448:Receptors, Dopamine D2; D050637:Receptors, Dopamine D3; D012694:Serine; D000242:Cyclic AMP; D015232:Dinoprostone; D005998:Glycine; D004298:Dopamine