title: Dearomatising rearrangements of lithiated thiophenecarboxamides.
abstract: Thiophene-3-carboxamides bearing allyl or benzyl substituents at nitrogen undergo dearomatising cyclisation on treatment with LDA. Rearrangements transform the dearomatised products into pyrrolinones, azepinones or partially saturated azepinothiophenes.
authors.affiliation: Department of Chemistry, University of Manchester, Oxford Road, Manchester, UK M13 9PL. j.p.clayden@man.ac.uk
authors.forename: Jonathan
authors.initials: J
authors.lastname: Clayden
authors.forename: Rachel
authors.initials: R
authors.lastname: Turnbull
authors.forename: Madeleine
authors.initials: M
authors.lastname: Helliwell
authors.forename: Ivan
authors.initials: I
authors.lastname: Pinto
mesh_terms: D018360:Crystallography, X-Ray; D008094:Lithium / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013876:Thiophenes / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D013876:Thiophenes; D008094:Lithium