title: Laser in situ keratomileusis to correct post-keratoplasty astigmatism; 1-step versus 2-step procedure.
abstract: OBJECTIVE
  To investigate the correction of post-penetrating keratoplasty (PKP) astigmatism using laser in situ keratomileusis (LASIK). Visual and refractive outcomes were evaluated after LASIK was performed in 1 step (lamellar cut and ablation in 1 procedure) or 2 steps (lamellar cut then ablation in 2 successive procedures).
  
  
  METHODS
  Department of Cornea and Refractive Surgery, Vissum-Instituto Oftalmológico de Alicante, University of Miguel Hernández, Alicante, Spain.
  
  
  METHODS
  In this prospective observational study, 22 consecutive eyes were divided into 2 groups depending on the LASIK procedure performed to correct post-PKP astigmatism. Group 1 (1-step LASIK) included 11 eyes and Group 2 (2-step LASIK), 11 eyes. The patients were followed for 6 months.
  
  
  RESULTS
  A statistically significant improvement was obtained in Group 2 with a mean vector analysis result of the cylinder of -4.37 diopters (D) +/- 1.79 (SD) (P = .018). In Group 1, the mean astigmatism correction was 2.38 +/- 1.71 D. The number of reoperations and residual refractive defects were significantly better in Group 2.
  
  
  CONCLUSIONS
  The 2-step technique improved the accuracy of excimer laser correction of post-PKP astigmatism.
authors.affiliation: Instituto Oftalmológico de Alicante, University of Miguel Hernández, Alicante, Spain. jlalio@oftalio.com
authors.forename: Jorge L
authors.initials: JL
authors.lastname: Alió
authors.forename: Jaime
authors.initials: J
authors.lastname: Javaloy
authors.forename: Amr A
authors.initials: AA
authors.lastname: Osman
authors.forename: Virgilio
authors.initials: V
authors.lastname: Galvis
authors.forename: Alejandro
authors.initials: A
authors.lastname: Tello
authors.forename: Hazem E
authors.initials: HE
authors.lastname: Haroun
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001251:Astigmatism / Q000209:etiology / Q000601:surgery*; D019781:Corneal Topography; D005260:Female; D006085:Graft Survival; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D015948:Keratoplasty, Penetrating / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011446:Prospective Studies; D012029:Refraction, Ocular / Q000502:physiology; D012449:Safety; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology