title: [Extrapleural pneumonectomy of malignant pleural mesothelioma].
abstract: We analyzed 7 patients with malignant pleural mesothelioma who underwent extrapleural pneumonectomy. Six men and a woman had a mean age of 65 years old. The postoperative mortality rate was 14% (1 death) and morbidity, 43% (3 cases). According to staging of International Mesothelioma Interest Group, 2 patients had stage I disease, 1 did stage II, 3 did stage III and 1 did stage IV. Local recurrences were found in 3 patients and metastasis in 2. In patients with local recurrences, 2 had irradiation with chemotherapy and 1, irradiation. In patients with recurrences of metastasis, 1 had chemotherapy and 1, supportive care. Seven patients with extrapleural pneumonectomy and 10 without surgery had median survivals of 16 months and 10 months, 1-year survival rates of 71% and 40% and 2-year survival rates of 57% and 0% respectively (p=0.071). Extrapleural pneumonectomy with adjuvant therapy could be effective treatment for malignant pleural mesothelioma.
authors.affiliation: Department of General Thoracic Surgery, Izumisano Municipal Hospital, Rinku General Medical Center, Izumisano, Japan.
authors.forename: Hyung-Eun
authors.initials: HE
authors.lastname: Yoon
authors.forename: K
authors.initials: K
authors.lastname: Nonaka
authors.forename: K
authors.initials: K
authors.lastname: Fukuhara
authors.forename: H
authors.initials: H
authors.lastname: Ueshima
authors.forename: T
authors.initials: T
authors.lastname: Sugiura
authors.forename: H
authors.initials: H
authors.lastname: Kaneda
authors.forename: S
authors.initials: S
authors.lastname: Shimamoto
authors.forename: M
authors.initials: M
authors.lastname: Imakita
authors.forename: K
authors.initials: K
authors.lastname: Iwase
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000601:surgery* / Q000628:therapy; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010997:Pleural Neoplasms / Q000601:surgery* / Q000628:therapy; D011013:Pneumonectomy / Q000379:methods*