The effect of rTMS over the cerebellum in normal human volunteers on peg-board movement performance.
Low frequency rTMS over the paramedian part of the right cerebellum was used to test the effects of TMS-induced disruption of the cerebellum on performance of the 10-hole pegboard task. A test group (n = 14) showed significantly increased movement times lasting about 3 min after the 5-min 1 Hz rTMS train, compared to a control group who received no rTMS (n = 14), tested in a parallel group design. The increase was greatest for the hand ipsilateral to the stimulation, but the difference between the two hands was not statistically significant. These results suggest that the rTMS affects cerebellar excitability and cause a short-lasting bilateral change in sensory-motor performance.
Miall
R C
RC
Behavioural Brain Sciences Centre, School of Psychology, University of Birmingham, Birmingham B152TT, UK. r.c.miall@bham.ac.uk
Christensen
L O D
LO
D000704:Analysis of Variance; D002531:Cerebellum / Q000502:physiology*; D004574:Electromagnetic Fields; D006801:Humans; D011597:Psychomotor Performance / Q000502:physiology*; D013997:Time Factors