Two novel dicoumaro-p-menthanes from Gerbera piloselloides (L.) CASS.
Two new type dicoumarins (dicoumaro-p-menthanes), named dibothrioclinins I (1) and II (2) were isolated from the roots and rhizomes of Gerbera piloselloides (L.) CASS., collected in Yunnan Province, China. Their structures were elucidated on the basis of MS, 1D ((1)H-NMR, (13)C-NMR, DEPT and NOE) and 2D ((1)H-(1)H COSY, HMQC, HMBC) NMR spectral analyses. The relative structures of the two compounds were established by NOE difference spectroscopy and further confirmed by single-crystal X-ray diffraction studies.
Xiao
Ying
Y
Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100-050, China.
Ding
Yi
Y
Li
Jian-Bei
JB
Nohara
Toshihiro
T
D019659:Asteraceae; D001728:Dicumarol / Q000737:chemistry* / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification*; D018517:Plant Roots; D027343:Rhizome
D004365:Drugs, Chinese Herbal; D001728:Dicumarol