title: [Assessment of disorders after chronic psychoactive drug abuse in patients hospitalized in detoxification units].
abstract: The aim of this study was the assessment of disorders after chronic intake of psychoactive drugs, like marijuana, amphetamine, ecstasy, cocaine and opiates. In 2002 in the Department of Clinical Toxicology detoxification unit were treated 117 chronic drug abusers. The 76 of them use the opiates predominantly, the next 41 persons (35 men, 6 women), were heavy abusers of psychostimulant drugs. In opiate abusers typical withdrawal signs and symptoms were observed. In the group of psychostimulants users, the mean time of marijuana use was 6 years, amphetamine--5 years. The cocaine was used rarely. Among 25 persons (61%) from these group the withdrawal syndrome were established. The excitation of neurovegetative system, depression, or psychomotor effects were observed. We concluded the necessity of estimation of neurobiological changes after using of psychostimulants and that more controlled research might uncover a clinically diagnosable withdrawal syndrome in human psychostimulants users.
authors.affiliation: Klinika Toksykologii KMPiChS, Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.
authors.forename: Jan
authors.initials: J
authors.lastname: Chrostek Maj
authors.forename: Stanisław
authors.initials: S
authors.lastname: Kroch
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Kamenczak
authors.forename: Andrej
authors.initials: A
authors.lastname: Polewka
authors.forename: Jadwiga
authors.initials: J
authors.lastname: Szerszeń-Motyka
mesh_terms: D000293:Adolescent; D000328:Adult; D000661:Amphetamine / Q000009:adverse effects; D019969:Amphetamine-Related Disorders / Q000175:diagnosis; D002188:Cannabis / Q000009:adverse effects; D003042:Cocaine / Q000009:adverse effects; D019970:Cocaine-Related Disorders / Q000175:diagnosis; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D002189:Marijuana Abuse / Q000175:diagnosis; D008875:Middle Aged; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000009:adverse effects; D009294:Narcotics / Q000009:adverse effects; D009293:Opioid-Related Disorders / Q000175:diagnosis* / Q000453:epidemiology; D011044:Poland / Q000453:epidemiology; D011619:Psychotropic Drugs / Q000009:adverse effects*; D016320:Substance Abuse Treatment Centers; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology
chemical_list: D009294:Narcotics; D011619:Psychotropic Drugs; D000661:Amphetamine; D003042:Cocaine; D018817:N-Methyl-3,4-methylenedioxyamphetamine