title: [Secondary surfactant deficiencies in extremely low birth weight premature infants].
abstract: Primary deficiency of surfactant is responsible for the respiratory distress syndrome and concerns premature neonates born before 33 weeks of gestation. However, newborns may develop respiratory disorders related to a secondary deficiency or dysfunction of surfactant. We report the course of three extremely low birth weight premature infants who experienced clinical respiratory decompensation at two weeks and showed a marked improvement after exogenous natural surfactant administration.
authors.affiliation: Service de pédiatrie II, médecine néonatale et réanimation pédiatrique, hôpital de Hautepierre, hôpitaux universitaires de Strasbourg, avenue Molière, 67098 Strasbourg cedex, France.
authors.forename: S
authors.initials: S
authors.lastname: Rivera
authors.forename: C
authors.initials: C
authors.lastname: Gaugler
authors.forename: C
authors.initials: C
authors.lastname: Langlet
authors.forename: F
authors.initials: F
authors.lastname: Villega
authors.forename: D
authors.initials: D
authors.lastname: Astruc
authors.forename: B
authors.initials: B
authors.lastname: Escande
authors.forename: P
authors.initials: P
authors.lastname: Kuhn
authors.forename: J
authors.initials: J
authors.lastname: Messer
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D011379:Prognosis; D011663:Pulmonary Surfactants / Q000627:therapeutic use*; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D011663:Pulmonary Surfactants