title: Endoscopic and surgical management of leakage and mediastinitis after esophageal surgery.
abstract: Due to the specialisation of esophageal surgery a significant reduction of post-surgical mortality was possible during the last few decades. Nevertheless a high complication rate of about 30% remains even in the hands of experienced surgeons. Anastomotic leakage has an incidence between 5 and 30% leading to serious postoperative morbidity. With a broad range of conservative and endoscopic therapeutic methods there is encouraging progress in shortening the time to closure of the leakage and reducing the risk of severe systemic complications such as sepsis or malnutrition. If conservative therapy fails, re-surgery remains as an ultima-ratio option.
authors.affiliation: III. Medizinische Klinik, Klinikum Augsburg, Department of Internal Medicine, Postfach 101920, D-86009 Augsburg, Germany. helmut.messmann@klinikum.augsburg.de
authors.forename: H
authors.initials: H
authors.lastname: Messmann
authors.forename: Werner
authors.initials: W
authors.lastname: Schmidbaur
authors.forename: Jürgen
authors.initials: J
authors.lastname: Jäckle
authors.forename: Alois
authors.initials: A
authors.lastname: Fürst
authors.forename: I
authors.initials: I
authors.lastname: Iesalnieks
mesh_terms: D000714:Anastomosis, Surgical; D003646:Debridement; D013505:Digestive System Surgical Procedures / Q000009:adverse effects*; D004322:Drainage; D004935:Esophageal Diseases / Q000601:surgery; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use; D006801:Humans; D008480:Mediastinitis / Q000209:etiology / Q000601:surgery*; D010289:Parenteral Nutrition, Total; D019736:Prostheses and Implants; D015607:Stents; D013536:Suture Techniques; D014138:Tracheoesophageal Fistula / Q000209:etiology / Q000601:surgery*
chemical_list: D015718:Fibrin Tissue Adhesive