title: [Affection on oxygen tension of the lens after vitrectomy].
abstract: OBJECTIVE
  To measure the oxygen tension (PO2) in the rabbit vitreous and lens and to investigate the mechanism by which it is controlled, the affection on oxygen tension of the lens after vitrectomy was studied.
  
  
  METHODS
  Using a fiber-optic oxygen sensor system, oxygen tension of the rabbit vitreous and lens was probed in vivo and oxygen permeability of posterior capsule was also measured on isolated rabbit lens.
  
  
  RESULTS
  It was found that with agreement with previous study, PO2 is relatively high and the PO2 gradient is large in vitreous body close to the retina whereas more than 0.5 mm away from the retina the vitreal PO2 is relatively low and the PO2 gradient is very shallow. Oxygen tension in the lens is asymmetric with the anterior being higher than the posterior and oxygen in the posterior lens being at the similar tension as the anterior vitreous behind the lens. The posterior capsule of the rabbit lens is relatively high in oxygen permeability.
  
  
  CONCLUSIONS
  The vitreous body plays a key role in maintaining a low and stable level of oxygen in the lens. After vitrectomy oxygen tension in the lens may increase.
authors.affiliation: People's Hospital Affiliated Beijing University, Beijing 100044, China.
authors.forename: Jianhong
authors.initials: J
authors.lastname: Liang
authors.forename: Lei
authors.initials: L
authors.lastname: Zheng
authors.forename: Changxian
authors.initials: C
authors.lastname: Yi
authors.forename: Irene
authors.initials: I
authors.lastname: Barbazetto
authors.forename: James
authors.initials: J
authors.lastname: Dillon
mesh_terms: D000818:Animals; D007903:Lens Capsule, Crystalline / Q000502:physiology; D007908:Lens, Crystalline / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism*; D010313:Partial Pressure; D011184:Postoperative Period; D011817:Rabbits; D014821:Vitrectomy; D014822:Vitreous Body / Q000378:metabolism*
chemical_list: D010100:Oxygen