Chronic granulomatous disease and peripheral ulcerative keratitis: a rare case of recurrent external ocular disease.
METHODS
We report a case of a 29-year-old lady, with known Chronic Granulomatous Disease, who presented with an acneiform scarring facial and trunk eruption and sore red eyes. Slitlamp examination showed limbal granulomas and adjacent peripheral ulcerative keratitis.


CONCLUSIONS
The authors are considering the possible causes of the keratitis. As there were no signs of blepharitis at the time of initial presentation, the keratitis was most likely mediated by the adjacent limbal granuloma, and not due to Staphylococcal hypersensitivity.


CONCLUSIONS
Although ocular involvement in CGD has been described before, this is the first article that describes limbal granulomata and peripheral ulcerative keratitis. Multidisciplinary management with longstanding oral antibiotic treatment, and topical combined antibiotic-steroid treatment were required to bring the condition under control.
Leroux
K
K
Department of Ophthalmology, Mayday University Hospital, London, UK. kathleen.leroux@uz.kuleuven.ac.be
Mallon
E
E
Ayliffe
W H
WH
D000328:Adult; D001706:Biopsy; D003320:Corneal Ulcer / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000473:pathology; D006801:Humans; D012867:Skin / Q000473:pathology