Is there a role for maintaining sinus rhythm in patients with atrial fibrillation?
Recent studies have indicated that outcomes in patients with atrial fibrillation who are managed with rate control and anticoagulation are similar to those in patients who have maintenance of sinus rhythm. These studies did not include important groups of patients with atrial fibrillation in whom antiarrhythmic therapy may be appropriate. This perspective argues for the maintenance of sinus rhythm and for the use of antiarrhythmic therapy that includes medications, invasive procedures, and a combination of both in appropriate patients.
Zimetbaum
Peter
P
Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.
Josephson
Mark E
ME
D000889:Anti-Arrhythmia Agents / Q000009:adverse effects / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000188:drug therapy / Q000628:therapy*; D003131:Combined Modality Therapy; D016903:Drug Monitoring; D006801:Humans
D000889:Anti-Arrhythmia Agents; D000925:Anticoagulants