title: Construction and evaluation of an average CT brain image for inter-subject registration.
abstract: An average CT brain image is constructed to serve as reference frame for inter-subject registration. A set of 96 clinical CT images is used. Registration includes translation, rotation, and anisotropic scaling. A temporary average based on a subset of 32 images is constructed. This image is used as reference for the iterative construction of the average CT image. This approach is computationally efficient and results in a consistent registration of the 96 images. Registration of new images to the average CT is more consistent than registration to a single CT image. The use of the average CT image is illustrated.
authors.affiliation: Image Sciences Institute, University Medical Center Utrecht, Room E01.335, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands. cynthia@isi.uu.nl
authors.forename: Cynthia
authors.initials: C
authors.lastname: Jongen
authors.forename: Josien P W
authors.initials: JP
authors.lastname: Pluim
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Nederkoorn
authors.forename: Max A
authors.initials: MA
authors.lastname: Viergever
authors.forename: Wiro J
authors.initials: WJ
authors.lastname: Niessen
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging*; D006801:Humans; D020521:Stroke / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods*