title: Crohn disease of the small bowel proximal to the terminal ileum: detection by MR-enteroclysis.
abstract: BACKGROUND
  Although Crohn disease (CD) can affect the entire alimentary tract, the proportion of patients with small-bowel inflammation proximal to the terminal ileum is still unclear. Magnetic resonance imaging (MRI) combined with small-bowel enteroclysis can detect inflammatory lesions of the small bowel. Hence, we applied MR-enteroclysis to assess the percentage of patients with small-bowel inflammation proximal to the terminal ileum among patients with CD and abdominal pain.
  
  
  METHODS
  Twenty-five consecutive patients with low, active CD of the colon and/or terminal ileum and episodes of abdominal pain were examined by both MR-enteroclysis and conventional enteroclysis. The findings of MR-enteroclysis were compared with endoscopic and histological results in the terminal ileum and conventional enteroclysis in the small bowel proximal to the terminal ileum.
  
  
  RESULTS
  In 13 of the 25 patients, inflammation of the small bowel proximal to the terminal ileum was shown by MR-enteroclysis, whereas in only 4 of the 25 patients, signs of inflammation of the small bowel proximal to the terminal ileum were shown by conventional enteroclysis, all of which were demonstrated by MR-enteroclysis. MR-enteroclysis confirmed the findings in 22 of 25 patients in whom endoscopy and histology had shown inflammation (16 of 18) or no inflammation (6 of 7) of the terminal ileum.
  
  
  CONCLUSIONS
  In symptomatic patients with CD even of low activity, inflammation of the small bowel proximal to the terminal ileum is frequent.
authors.affiliation: Department of Medicine II, Institute of Clinical Radiology, Klinikum Grosshadern, University of Munich, Germany. thomas.ochsenkuehn@med.uni-muenchen.de
authors.forename: T
authors.initials: T
authors.lastname: Ochsenkühn
authors.forename: K
authors.initials: K
authors.lastname: Herrmann
authors.forename: S O
authors.initials: SO
authors.lastname: Schoenberg
authors.forename: M F
authors.initials: MF
authors.lastname: Reiser
authors.forename: B
authors.initials: B
authors.lastname: Göke
authors.forename: M
authors.initials: M
authors.lastname: Sackmann
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D003287:Contrast Media / Q000008:administration & dosage; D003424:Crohn Disease / Q000175:diagnosis*; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007082:Ileum / Q000473:pathology*; D007091:Image Processing, Computer-Assisted; D007150:Immunohistochemistry; D007583:Jejunum / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011336:Probability; D011446:Prospective Studies; D012494:Sampling Studies; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA