New sesterterpenes from the sponge Smenospongia sp.
Five new sesterterpenes, three scalarane-type (1-3) and two linear furanosesterterpenes (4, 5), were isolated from the marine sponge Smenospongia sp. collected from Gagu-Do, Korea. The structures of the new compounds, which exhibited moderate cytotoxicity toward the human leukemia cell line K562, were determined from an analysis of spectroscopic data.
Rho
Jung-Rae
JR
Marine Natural Products Laboratory, Korea Ocean Research & Development Institute, Ansan PO Box 29, Seoul 425-600.
Lee
Hyi-Seung
HS
Shin
Hee Jae
HJ
Ahn
Jong-Woong
JW
Kim
Ji-Yun
JY
Sim
Chung J
CJ
Shin
Jongheon
J
D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D020014:K562 Cells; D007723:Korea; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry*; D054830:Sesterterpenes; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000970:Antineoplastic Agents; D054830:Sesterterpenes; D013729:Terpenes