[Study progress on determination of environmental trace toxicants by immunosensor].
Along with the advances in immunoassay and sensing techniques, the immunosensors based on specific immunoreaction and immobilized antibody (antigen) as recognition element were developed. They can be used for real-time, in-vivo and on-the-spot determination of pesticides, industrial organic pollutants, heavy metals, biotoxins, etc. with high sensitivity and selectivity. They possess a great potential for environmental monitoring. The working mechanism, fabrication and classification of immunosensor are briefly introduced in this paper. The latest study progress on immobilization methods and sensing techniques of immunosensor for determination of trace toxicants is reviewed. The application of immunosensor in environmental monitoring and the future development are also discussed.
Tang
Lin
L
Department of Environmental Science and Engineering, Hunan University, Changsha 410082, China. etanglin@hotmail.com
Zeng
Guang-ming
GM
Huang
Guo-he
GH
Niu
Cheng-gang
CG
D000937:Antigen-Antibody Reactions; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods; D004784:Environmental Monitoring / Q000295:instrumentation / Q000379:methods*; D004785:Environmental Pollutants / Q000032:analysis*; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods*; D019216:Metals, Heavy / Q000032:analysis / Q000276:immunology; D009930:Organic Chemicals / Q000032:analysis / Q000276:immunology; D010575:Pesticides / Q000032:analysis / Q000276:immunology
D004785:Environmental Pollutants; D019216:Metals, Heavy; D009930:Organic Chemicals; D010575:Pesticides