title: Systemic dermatitis and obstructive respiratory syndrome following occupational sensitization to trichloroethylene.
abstract: We present a derma-respiratory syndrome in a patient occupationally exposed to trichloroethylene (TCE). At the beginning of its industrial use trichloroethylene was considered harmless. But, in time it showed a high noxious capacity. It produces an important and various pathology, which evolves as acute or chronic disease. The case we present shows that trichloroethylene can induce cutaneous pathology that excels contact dermatitis. It also proves that trichloroethylene can produce systemic effects (obstructive respiratory syndrome). The particularity of the case is based on the succession of the events, first the cutaneous and then the respiratory effects. A long period of time was necessary for the installation of the symptoms (for cutaneous and bronchial sensitization to take place). The case presented is the proof that trichloroethylene's great toxicity cannot be doubted and that the clinical forms due to sensitization to trichloroethylene can be dramatic.
authors.affiliation: Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. agrirascu@yahoo.com
authors.forename: Agripina
authors.initials: A
authors.lastname: Raşcu
authors.forename: Letiţia
authors.initials: L
authors.lastname: Bucur
authors.forename: Eugenia
authors.initials: E
authors.lastname: Naghi
authors.forename: B
authors.initials: B
authors.lastname: Drăghici
mesh_terms: D000328:Adult; D003872:Dermatitis / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000139:chemically induced*; D009784:Occupational Diseases / Q000139:chemically induced*; D012997:Solvents / Q000009:adverse effects*; D014241:Trichloroethylene / Q000009:adverse effects*
chemical_list: D012997:Solvents; D014241:Trichloroethylene