title: An uncommon presentation: chronic meningococcaemia associated with cholestatic hepatitis in a Turkish child.
abstract: Chronic meningococcaemia is a very rare clinical manifestation of invasive infection by Neisseria meningitidis. A 9-year-old girl was admitted to our clinic with complaints of fever, headache, arthralgia, and maculopapular rash. The diagnosis was made by the growth of Neisseria meningitidis in the blood cultures. Four days after admission, liver function tests were increased and were compatible with cholestatic hepatitis. Thereafter, the patient was successfully treated and symptoms were completely resolved. To our knowledge, there have been no previous reports of Neisseria meningitidis causing cholestatic hepatitis. Herein, we present an unusual child patient with chronic meningococcaemia associated with cholestatic hepatitis.
authors.affiliation: Department of Pediatrics, Ondokuz Mayis University Faculty of Medicine, Samsun,Turkey. mtotan@omu.edu.tr
authors.forename: Mehmet
authors.initials: M
authors.lastname: Totan
authors.forename: Gulcan
authors.initials: G
authors.lastname: Yildiz
authors.forename: Ayhan Gazi
authors.initials: AG
authors.lastname: Kalayci
mesh_terms: D016470:Bacteremia / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D002648:Child; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D041781:Jaundice, Obstructive / Q000150:complications* / Q000382:microbiology; D008589:Meningococcal Infections / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D009345:Neisseria meningitidis / Q000187:drug effects / Q000302:isolation & purification; D010400:Penicillin G / Q000627:therapeutic use; D035583:Rare Diseases; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014421:Turkey
chemical_list: D010400:Penicillin G