title: Guanidines as a nitrogen source for direct conversion of epoxides to aziridines.
abstract: Direct conversion of epoxides to aziridines was achieved with guanidines as a nitrogen source. Stereochemical inversion at the chiral centers of epoxides was observed without loss of optical purity.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi, Inage, Chiba 263-8522, Japan.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Tsuchiya
authors.forename: Takuya
authors.initials: T
authors.lastname: Kumamoto
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Ishikawa
mesh_terms: D001388:Aziridines / Q000138:chemical synthesis*; D004852:Epoxy Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D006146:Guanidines / Q000737:chemistry*; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*
chemical_list: D001388:Aziridines; D004852:Epoxy Compounds; D006146:Guanidines; D009584:Nitrogen