title: Incidence of glaucoma in patients with uveitis.
abstract: OBJECTIVE
  To evaluate the incidence of glaucoma and elevation of intraocular pressure (IOP) in patients with inflammatory eye disease.
  
  
  METHODS
  Retrospective review of medical records of 391 consecutive patients with uveitis attending a uveitis clinic of an academic Department of Ophthalmology from January 1999 to August 2002. Demographic, ocular and systemic variables were recorded. The diagnosis and treatment of uveitis were recorded. Uveitis was classified according to standard anatomic, etiological and clinical criteria. "Glaucoma" was defined as elevated IOP (>21 mm Hg) or glaucomatous optic nerve damage requiring medical and/or surgical anti-glaucoma treatment. Kaplan-Maier analysis and log-rank tests were used to evaluate and compare the incidence of glaucoma.
  
  
  RESULTS
  The incidence of glaucoma as defined above at 3 and 12 months after acute uveitis was 7.6%. In patients with chronic uveitis (n = 337), the incidence of glaucoma at 1 and 5 years was 6.5% and 11.1%, respectively. There was no statistically significant difference in the incidence of glaucoma between different types of uveitis, idiopathic versus non-idiopathic, and among anterior, intermediate, posterior and panuveitis. Visual loss occurred more frequently in patients with glaucoma than in patients without glaucoma.
  
  
  CONCLUSIONS
  In patients with chronic inflammatory eye disease, the presence of glaucoma was associated with an increasing risk of visual loss. The incidence of glaucoma increased with time and was similar among the different types of uveitis.
authors.affiliation: Department of Ophthalmology, Aberdeen Royal Infirmary, University of Aberdeen, Foresterhill, UK.
authors.forename: Piergiorgio
authors.initials: P
authors.lastname: Neri
authors.forename: Augusto
authors.initials: A
authors.lastname: Azuara-Blanco
authors.forename: John V
authors.initials: JV
authors.lastname: Forrester
mesh_terms: D000208:Acute Disease; D000328:Adult; D002908:Chronic Disease; D005260:Female; D005901:Glaucoma / Q000150:complications / Q000453:epidemiology* / Q000209:etiology*; D006801:Humans; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D014605:Uveitis / Q000150:complications*; D014786:Vision Disorders / Q000453:epidemiology / Q000209:etiology