title: Three isocoumarins and a benzofuran from the cultured lichen mycobionts of Pyrenula sp.
abstract: The spore-derived mycobionts of the lichen Pyrenula sp. were cultivated on a malt-yeast extract medium supplemented with 10% sucrose. The investigation of their metabolites resulted in isolation of four compounds, three isocoumarins and a biogenetically related benzofuran; their structures were determined by spectroscopic methods.
authors.affiliation: Kobe Pharmaceutical University, 4-19-1, Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Takenaka
authors.forename: Takao
authors.initials: T
authors.lastname: Tanahashi
authors.forename: Naotaka
authors.initials: N
authors.lastname: Nagakura
authors.forename: Atsuko
authors.initials: A
authors.lastname: Itoh
authors.forename: Nobuo
authors.initials: N
authors.lastname: Hamada
mesh_terms: D001572:Benzofurans / Q000737:chemistry* / Q000302:isolation & purification; D003374:Coumarins / Q000737:chemistry*; D049934:Isocoumarins; D008011:Lichens / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure
chemical_list: C495550:(E)-5,8-dihydroxy-3-(1-pentenyl)isocoumarin; C495551:(E)-5-hydroxy-8-methoxy-3-(1-pentenyl)isocoumarin; D001572:Benzofurans; D003374:Coumarins; D049934:Isocoumarins; C495552:cis-3,4-dihydro-4,5,8-trihydroxy -3-(1-pentenyl)isocoumarin; C495553:pyrenulafuran