Atrophic dermatofibrosarcoma protuberans: a case report and reappraisal of the literature.
Dermatofibrosarcoma protuberans (DFSP) is an uncommon cutaneous malignancy. Unusual presentations described as atrophic have been documented. A case of DFSP with both clinical and histologic atrophy is presented, and all cases purporting atrophy with this tumor are reviewed. Meaningful trends are extracted from this data. In addition, the imprecise use of the term atrophic in regard to DFSP is clarified. We maintain that the variant of atrophic DFSP that mimics atrophoderma or anetoderma, as in this case, is the rarest variant of atrophic DFSP. Atrophic DFSP should be in the differential for depressed lesions on the trunks of women or on the lower extremities of children.
Sheehan
Daniel J
DJ
Section of Dermatology, Medical College of Georgia, 1004 Chafee Ave, Augusta, GA 30904, USA.
Madkan
Vandana
V
Strickling
William A
WA
Peterson
Christopher M
CM
D000328:Adult; D018952:Antigens, CD34 / Q000032:analysis; D001284:Atrophy; D014408:Biomarkers, Tumor / Q000032:analysis; D018223:Dermatofibrosarcoma / Q000737:chemistry / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D015580:Mohs Surgery; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome
D018952:Antigens, CD34; D014408:Biomarkers, Tumor