title: Pure post-stroke cerebellar cognitive affective syndrome: a case report.
abstract: Cerebellar pathology commonly shows important motor signs and less evident cognitive dysfunction. The 'cerebellar cognitive affective syndrome' is characterised by impairment on executive function, spatial cognition, language and behaviour. We report the case of a man with acute onset of transitory motor features and severe mental disorders. Cranial CT and brain MRI revealed extended cerebellar lesions. Neuropsychological assessment disclosed deficits of attention, executive function and memory. Auditory event-related potentials showed abnormal P300. These data suggest a pure "cerebellar cognitive affective syndrome"and strengthen the hypothesis of cerebellar cognitive function modulation.
authors.affiliation: Institute of Clinical Neurology, University of Sassari, Viale San Pietro 10, I-07100, Sassari, Italy. kpaulus@hotmail.com
authors.forename: K S
authors.initials: KS
authors.lastname: Paulus
authors.forename: I
authors.initials: I
authors.lastname: Magnano
authors.forename: M
authors.initials: M
authors.lastname: Conti
authors.forename: P
authors.initials: P
authors.lastname: Galistu
authors.forename: M
authors.initials: M
authors.lastname: D'Onofrio
authors.forename: W
authors.initials: W
authors.lastname: Satta
authors.forename: I
authors.initials: I
authors.lastname: Aiello
mesh_terms: D000368:Aged; D001288:Attention / Q000502:physiology; D002526:Cerebellar Diseases / Q000209:etiology* / Q000473:pathology / Q000523:psychology; D002531:Cerebellum / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D003072:Cognition Disorders / Q000209:etiology* / Q000473:pathology / Q000523:psychology; D018913:Event-Related Potentials, P300 / Q000502:physiology; D006801:Humans; D007806:Language Disorders / Q000209:etiology / Q000473:pathology / Q000523:psychology; D008279:Magnetic Resonance Imaging; D008297:Male; D008569:Memory Disorders / Q000150:complications / Q000473:pathology / Q000523:psychology; D019964:Mood Disorders / Q000209:etiology* / Q000473:pathology / Q000523:psychology; D009483:Neuropsychological Tests; D020521:Stroke / Q000150:complications* / Q000473:pathology / Q000523:psychology; D014057:Tomography, X-Ray Computed