title: Diversity of toxic shock syndrome toxin 1-positive Staphylococcus aureus isolates.
abstract: Staphylococcus aureus isolates from women with nasal, anal, or vaginal colonization were evaluated for population diversity by pulsed-field gel electrophoresis. Cluster analysis of restriction patterns revealed diversity indices of 0.89 and 0.99 for toxic shock syndrome toxin 1-positive and -negative isolates, respectively. Toxin-producing strains were isolated more frequently from the nares than from other sites.
authors.affiliation: Channing Laboratory, Department of Pathology and Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachsetts 02115, USA. jwarner@rics.bwh.harvard.edu
authors.forename: John E
authors.initials: JE
authors.lastname: Warner
authors.forename: Andrew B
authors.initials: AB
authors.lastname: Onderdonk
mesh_terms: D001003:Anal Canal / Q000382:microbiology; D001427:Bacterial Toxins / Q000378:metabolism*; D015252:Deoxyribonucleases, Type II Site-Specific; D016521:Electrophoresis, Gel, Pulsed-Field; D004768:Enterotoxins / Q000378:metabolism*; D005260:Female; D014644:Genetic Variation; D006801:Humans; D009296:Nasal Cavity / Q000382:microbiology; D015183:Restriction Mapping; D013203:Staphylococcal Infections / Q000382:microbiology; D013211:Staphylococcus aureus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D018089:Superantigens / Q000378:metabolism*; D014621:Vagina / Q000382:microbiology
chemical_list: D001427:Bacterial Toxins; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal; C025651:CCCGGG-specific type II deoxyribonucleases; D015252:Deoxyribonucleases, Type II Site-Specific