[Effects of repeated intraperitoneal CDDP chemotherapy for the prevention of T3 and T4 gastric cancer].
We studied the significance of repeated intraperitoneal CDDP administration, as adjuvant chemotherapy, for the prevention of T3 and T4 gastric cancer. Fifty-two patients who had been operated as Curability B were divided into the following two groups, and the data on survival rate, median survival time and interval of "free of recurrence" were accumulated and analyzed. Group A consisted of nineteen patients treated with intraperitoneal CDDP administration and oral anticancer drugs. Group B were treated with systemic chemotherapy. Group A was superior to Group B in comparing the analyzed data. These results suggested that repeated intraperitoneal CDDP chemotherapy for the prevention of T3 and T4 advanced gastric cancer would improve survival rate.
Yano
Shuya
S
Dept. of Surgery, Hiroshima City Hospital.
Ninomiya
Motoki
M
Sasaki
Hiroshi
H
Umeoka
Tatsuo
T
Harano
Masao
M
Aoki
Hideki
H
Onoda
Tadashi
T
Shiozaki
Shigehiro
S
Ohno
Satoshi
S
Higaki
Kenji
K
Takakura
Norihisa
N
D000284:Administration, Oral; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002945:Cisplatin / Q000008:administration & dosage*; D018450:Disease Progression; D018572:Disease-Free Survival; D004334:Drug Administration Schedule; D006801:Humans; D007263:Infusions, Parenteral; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000401:mortality
D000970:Antineoplastic Agents; D002945:Cisplatin