[The effects of extracts from Herba Lagopsis on lymph microcirculation of acute blood stasis rats].
OBJECTIVE
To observe the effects of the extracts from Herba Lagopsis (HLE) on lymph microcirculation of acute blood stasis rats.


METHODS
The acute blood stasis model was made by iv dextran (10 ml/kg) within 1 min. After 6 minutes, HLE(1.0g/kg) was given intravenously to the treatment group and the same volume of NS was done in the normal control group. The changes of contractility of mesenteric micro-lymphatics (ML) was observed by using a vital microscope with TV recorder.


RESULTS
HLE could markedly improve the ML spontaneous constraction frequency, lymphatics constractive activity (Index I), total lymphatics constractive activity (Index II) and lymphatics dynamics (L. D-Index) (P < 0.05 approximately 0.01).


CONCLUSIONS
HLE played an important role in lymph microcirculation of acute blood stasis rats.
Zhang
Limin
L
Hebei North College, Zhangjiakou 075029.
Jiang
Hua
H
Liu
Yankai
Y
Zhang
Xuefeng
X
Niu
Chunyu
C
Zhang
Wanming
W
D000208:Acute Disease; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D019686:Lamiaceae / Q000737:chemistry*; D008208:Lymphatic System / Q000098:blood supply / Q000187:drug effects*; D008297:Male; D008643:Mesentery / Q000098:blood supply / Q000187:drug effects*; D008833:Microcirculation / Q000187:drug effects* / Q000503:physiopathology; D018715:Microscopy, Video; D009119:Muscle Contraction / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar
D004365:Drugs, Chinese Herbal