title: Conversion of atrial fibrillation to sinus rhythm during landiolol infusion.
abstract: A 71-year-old woman with a history of persistent atrial fibrillation underwent clipping of a ruptured cerebral artery aneurysm. During the surgery her cardiac rhythm was atrial fibrillation and the ventricular rate increased to 130 beats.min(-1). Administration of landiolol was started with 1-min loading infusion at 0.125 mg.kg(-1).min(-1) and continuous infusion at 0.04 mg.kg(-1).min(-1), which was effective in controlling the ventricular rate without causing hypotension. Approximately 120 min after the landiolol infusion was started, the atrial fibrillation was converted to sinus rhythm. Her sinus rhythm was maintained until she left the operating room, even after discontinuation of landiolol.
authors.affiliation: Department of Anesthesiology and Critical Care Medicine, Funabashi Municipal Medical Center, Funabashi, Japan.
authors.forename: Taku
authors.initials: T
authors.lastname: Mayahara
authors.forename: Maria
authors.initials: M
authors.lastname: Goto
authors.forename: Mikako
authors.initials: M
authors.lastname: Sato
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kanazawa
authors.forename: Shinji
authors.initials: S
authors.lastname: Isomine
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nakajima
authors.forename: Koji
authors.initials: K
authors.lastname: Sakaida
mesh_terms: D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage*; D001281:Atrial Fibrillation / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D002532:Intracranial Aneurysm / Q000601:surgery; D007430:Intraoperative Care; D009025:Morpholines / Q000008:administration & dosage*; D014508:Urea / Q000008:administration & dosage / Q000031:analogs & derivatives*
chemical_list: D000889:Anti-Arrhythmia Agents; D009025:Morpholines; C077049:landiolol; D014508:Urea