title: Relation of left ventricular sphericity to 10-year survival after acute myocardial infarction.
abstract: After ST-elevation myocardial infarction, the association between left ventricular sphericity (measured by biplane ventriculography) and survival rate at a median of 6.5 years was determined in 825 patients. The highest tertile of sphericity (vs the lowest and middle tertiles) was associated with a decreased 10-year survival rate in patients who had anterior myocardial infarction (p = 0.002), inferior myocardial infarction (p = 0.011), Thrombolysis In Myocardial Infarction (TIMI) grade 3 flow (p = 0.005), or TIMI grade 0 to 2 flow (p = 0.001) in the infarct artery. The independent multivariate predictors of a 10-year survival rate were ejection fraction (p = 0.002), treadmill exercise duration (p = 0.004), biplane left ventricular sphericity index (p = 0.032), age (p = 0.043), and end-systolic volume index (p = 0.047), but not TIMI flow grade.
authors.affiliation: Cardiology Department, Green Lane Hospital, Auckland, New Zealand.
authors.forename: Selwyn P
authors.initials: SP
authors.lastname: Wong
authors.forename: John K
authors.initials: JK
authors.lastname: French
authors.forename: Anna-Maria
authors.initials: AM
authors.lastname: Lydon
authors.forename: Samuel O M
authors.initials: SO
authors.lastname: Manda
authors.forename: Wanzhen
authors.initials: W
authors.lastname: Gao
authors.forename: Noel G
authors.initials: NG
authors.lastname: Ashton
authors.forename: Harvey D
authors.initials: HD
authors.lastname: White
mesh_terms: D002932:Cineangiography; D005080:Exercise Test; D005260:Female; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality* / Q000473:pathology / Q000503:physiopathology; D015635:Radionuclide Ventriculography; D016032:Randomized Controlled Trials as Topic; D013318:Stroke Volume; D015996:Survival Rate; D016277:Ventricular Function, Left; D020257:Ventricular Remodeling