title: Cross sections of electron inelastic interactions in DNA.
abstract: The cross sections of electron inelastic interaction in DNA are calculated using the dielectric response theory and Penn statistical approximation, with the exchange correction included. An empirical approach to obtain optical energy loss function is given for the organic compounds without available optical data. Comparisons of the calculated data with available experimental and theoretical results have been done to show the reliability of the approach proposed in this work. Using this approach, the total inelastic cross sections for five bases: guanine, adenine, thymine, cytosine and uracil have been calculated in the energy range of E< or =10 keV and compared with those recently obtained with the Deutsch-Mark formalism and the Binary-Encounter-Bethe model, respectively. An equivalent unit of the DNA molecule is constructed according to the contents of A-T and G-C base pairs in DNA, and is divided into five constituents, i.e. sugar-phosphate and four bases. The total inelastic cross sections for the constructed unit of the DNA molecule and its constituents have also been calculated.
authors.affiliation: School of Electrical Engineering, Shandong University (southern campus), 250061 Jinan, Shandong, PR China. tzy@sdu.edu.cn
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Tan
authors.forename: Yueyuan
authors.initials: Y
authors.lastname: Xia
authors.forename: Xiangdong
authors.initials: X
authors.lastname: Liu
authors.forename: Mingwen
authors.initials: M
authors.lastname: Zhao
authors.forename: Yanju
authors.initials: Y
authors.lastname: Ji
authors.forename: Feng
authors.initials: F
authors.lastname: Li
authors.forename: Boda
authors.initials: B
authors.lastname: Huang
mesh_terms: D001665:Binding Sites; D003198:Computer Simulation; D004247:DNA / Q000737:chemistry* / Q000528:radiation effects*; D004249:DNA Damage; D004307:Dose-Response Relationship, Radiation; D004548:Elasticity; D004583:Electrons; D018499:Linear Energy Transfer; D008956:Models, Chemical; D008958:Models, Molecular; D015233:Models, Statistical; D009711:Nucleotides / Q000737:chemistry / Q000528:radiation effects; D011829:Radiation Dosage
chemical_list: D009711:Nucleotides; D004247:DNA