Massive congenital intracranial teratoma: perioperative coagulation impairment.
Massive congenital intracranial teratoma is a rare neoplasm with a poor prognosis. Surgery may be curative only if complete resection can ben obtained. Several single case reports have been published in the pediatric literature, mostly focusing on prenatal diagnosis. The authors describe six patients with congenital intracranial teratoma treated at their institution in the past decade. Perioperatively, a marked hemostatic derangement was observed in three of them undergoing surgery: the pathophysiology of this complication is discussed. The surgical indication itself represents an ethical dilemma when treating a large intracranial tumor with partial destruction and replacement of brain structures.
Piastra
Marco
M
Pediatric Intensive Care Unit, Catholic University Medical School, Rome, Italy. xoct01@yahoo.it
Decarolis
Maria Pia
MP
Tempera
Alessia
A
Caresta
Elena
E
Polidori
Giancarlo
G
Chiaretti
Antonio
A
Pietrini
Domenico
D
Ruggiero
Antonio
A
Caldarelli
Massimo
M
Di Rocco
Concezio
C
D000328:Adult; D001777:Blood Coagulation; D001932:Brain Neoplasms / Q000151:congenital* / Q000175:diagnosis / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006470:Hemorrhage; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011296:Prenatal Diagnosis; D013724:Teratoma / Q000151:congenital* / Q000175:diagnosis / Q000601:surgery