Unexpected cross-coupling reaction between o-chloroaryl ketones and organomanganese reagents.
Alkyl- and arylmanganese reagents react with o-chloro or o-bromoaryl ketones to give the substituted ketones in high yields. The cross-coupling reaction is performed under mild conditions (-60 to +40 degrees C, 30 min to 4 h) and takes place with excellent chemoselectivity. [reaction: see text]
Cahiez
Gérard
G
Laboratoire de Chimie Organique Sélective et de Chimie Organométallique (SOSCO), UMR 8123 CNRS-UCP-ESCOM, 13 Boulevard de l'Hautil, F-95092 Cergy-Pontoise, France. gerard.cahiez@chim.u-cergy.fr
Luart
Denis
D
Lecomte
Fabien
F