title: [Damage to erythrocyte membranes induced by high-intensity ultrasound].
abstract: The effect of high-intensity ultrasound (11.2-54.2 W/cm2, frequency 36 kHz) on the structural and functional state of erythrocytes was investigated. It was shown that, at short-term action of the ultrasound (up to 1 min), the dose-dependent hemolysis of erythrocytes occurs. It was found that the exposure to ultrasound of high intensity (54.2 W/cm2) leads to the disruption of the structural state of erythrocyte membranes, which manifests itself in a change of microviscosity of the lipid bilayer of membranes and inhibition of the activity of the lipid-dependent membrane-bound enzyme acetylcholinesterase.
authors.forename: I E
authors.initials: IE
authors.lastname: Adzerikho
authors.forename: N M
authors.initials: NM
authors.lastname: Kozlova
authors.forename: A N
authors.initials: AN
authors.lastname: Antonovich
authors.forename: G P
authors.initials: GP
authors.lastname: Zubritskaia
authors.forename: E I
authors.initials: EI
authors.lastname: Slobozhanina
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism; D004910:Erythrocyte Membrane / Q000737:chemistry* / Q000201:enzymology*; D006461:Hemolysis; D006801:Humans; D008051:Lipid Bilayers / Q000378:metabolism; D014465:Ultrasonics
chemical_list: D008051:Lipid Bilayers; D000110:Acetylcholinesterase