title: A microwave-assisted click chemistry synthesis of 1,4-disubstituted 1,2,3-triazoles via a copper(I)-catalyzed three-component reaction.
abstract: A microwave-assisted three-component reaction was used to prepare a series of 1,4-disubstituted-1,2,3-triazoles from corresponding alkyl halides, sodium azide, and alkynes. This procedure eliminates the need to handle organic azides, as they are generated in situ, making this already powerful click process even more user-friendly and safe.
authors.affiliation: Department of Chemistry, University of Leuven, Celestijnenlaan 200F, B-3001 Leuven, Belgium.
authors.forename: Prasad
authors.initials: P
authors.lastname: Appukkuttan
authors.forename: Wim
authors.initials: W
authors.lastname: Dehaen
authors.forename: Valery V
authors.initials: VV
authors.lastname: Fokin
authors.forename: Erik
authors.initials: E
authors.lastname: Van der Eycken