Urinary excretion of vitamin A in critically ill patients complicated with acute renal failure.
OBJECTIVE
Study the possible excretion of vitamin A in urine of critically ill patients complicated with acute renal failure.


METHODS
Nine Intensive Care Unit patients, age 71.2 +/- 15.7 (mean +/- SD) with acute renal failure were studied. Urinary retinol, creatinine, protein, albumin, and serum creatinine were measured.


RESULTS
All patients excreted retinol in urine; individual values ranged from 0.007 to 0.379 micromol retinol/mmol creatinine. There was no correlation of urinary retinol/creatinine ratio with serum creatinine or with urinary protein/creatinine and albumin/creatinine ratios.


CONCLUSIONS
Excretion of retinol in urine may be indicative of acute renal failure in critically ill patients.
Gavrilov
Vladimir
V
Pediatric Pharmacology Laboratory, Soroka Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. vladimirgav@hotmail.com
Weksler
Natan
N
Ahmed
Ahmed
A
Gorodischer
Rafael
R
D058186:Acute Kidney Injury / Q000652:urine*; D000368:Aged; D000369:Aged, 80 and over; D016638:Critical Illness; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014801:Vitamin A / Q000652:urine*
D014801:Vitamin A