Latency of onset of de novo myelodysplastic syndromes.
The latency of onset of de novo myelodysplastic syndromes (MDS) is unknown. We report a retrospective analysis of blood counts from patients with MDS and acute myeloid leukemia (AML), and demonstrate temporal differences in rates of change of hemoglobin concentration and mean cell volume within 2-3 years of diagnosis, indicative of the earliest evidence of disease.
Wu
Pei-shan
PS
Hay
Annette E
AE
Thomas
Giles E
GE
Bowen
David T
DT
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004909:Erythrocyte Indices; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000097:blood / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000097:blood* / Q000175:diagnosis; D012189:Retrospective Studies