Stereoconservative Negishi arylation and alkynylation as an efficient approach to enantiopure 2,2'-diarylated 1,1'-binaphthyls.
Negishi arylation and alkynylation of easily synthesized chiral 2,2'-diodo-1,1'-binaphthyl rapidly proceeds in refluxing THF utilizing controlled microwave irradiation, affording enantiopure 2,2'-diarylated 1,1'-binaphthyls in good to excellent yields.
Krascsenicsová
Katarína
K
Department of Organic Chemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Slovak Republic.
Walla
Peter
P
Kasák
Peter
P
Uray
Georg
G
Kappe
C Oliver
CO
Putala
Martin
M