title: The occurrence of Guillain-Barre syndrome within families.
abstract: This report describes 12 Dutch families of which at least two members have had Guillain-Barre syndrome (GBS). The authors observed an earlier onset of GBS in successive generations. The occurrence of GBS within families suggests a role for genetic factors in the pathogenesis of GBS.
authors.affiliation: Department of Neurology, Room Ee 2230, Erasmus Medical Center, PO Box 1738, 3000 DR Rotterdam, The Netherlands. c.geleijns@erasmusmc.nl
authors.forename: K
authors.initials: K
authors.lastname: Geleijns
authors.forename: B A
authors.initials: BA
authors.lastname: Brouwer
authors.forename: B C
authors.initials: BC
authors.lastname: Jacobs
authors.forename: J J
authors.initials: JJ
authors.lastname: Houwing-Duistermaat
authors.forename: C M
authors.initials: CM
authors.lastname: van Duijn
authors.forename: P A
authors.initials: PA
authors.lastname: van Doorn
mesh_terms: D000328:Adult; D017668:Age of Onset; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D020022:Genetic Predisposition to Disease; D020275:Guillain-Barre Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D010375:Pedigree