Xylazine-midazolam-ketamine versus medetomidine-midazolam-ketamine anesthesia in captive Siberian tigers (Panthera tigris altaica).
Two alpha2-adrenoceptor agents, xylazine and medetomidine, in combination with midazolam and ketamine safely and effectively immobilized Siberian tigers (Panthera tigris altaica). The medetomidine protocol used smaller drug volumes, and induction and recovery times were shorter. Although cardiopulmonary abnormalities were noted, none were likely to be life threatening.
Curro
Thomas G
TG
Henry Doorly Zoo, 3701 S 10th Street, Omaha, Nebraska 68107, USA.
Okeson
Danelle
D
Zimmerman
Dawn
D
Armstrong
Douglas L
DL
Simmons
Lee G
LG
D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage*; D019162:Anesthetics, Combined / Q000008:administration & dosage*; D000778:Anesthetics, Dissociative / Q000008:administration & dosage*; D000818:Animals; D000836:Animals, Zoo / Q000502:physiology; D005260:Female; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D007103:Immobilization / Q000379:methods / Q000662:veterinary; D007273:Injections, Intramuscular / Q000662:veterinary; D007649:Ketamine / Q000008:administration & dosage; D008297:Male; D020926:Medetomidine / Q000008:administration & dosage; D008874:Midazolam / Q000008:administration & dosage; D046010:Tigers / Q000502:physiology*; D014991:Xylazine / Q000008:administration & dosage
D000316:Adrenergic alpha-Agonists; D019162:Anesthetics, Combined; D000778:Anesthetics, Dissociative; D006993:Hypnotics and Sedatives; D014991:Xylazine; D007649:Ketamine; D020926:Medetomidine; D008874:Midazolam