title: Determinants of quality of life in patients with psoriasis: a study from the US population.
abstract: BACKGROUND
  Psoriasis is a common disease with substantial effects on quality of life. Few quality of life studies have been performed in psoriasis patients from the general US population.
  
  
  OBJECTIVE
  To describe the determinants of quality of life in psoriasis patients from the US population.
  
  
  METHODS
  Patients were randomly selected from the US population. Patients who identified themselves as having been diagnosed with psoriasis by a physician were invited to complete a more detailed survey about quality of life.
  
  
  RESULTS
  Two hundred sixty-six psoriasis patients from the US population completed the detailed survey. Body surface area showed the strongest association with decrements in quality of life (Spearman 0.50, P < .0001). Younger patients and female patients also had statistically significant reductions in quality of life. Increasing psoriasis severity was associated with seeking care from multiple physicians and having decrements in income.
  
  
  CONCLUSIONS
  Patients with more extensive skin involvement have greater reductions in quality of life. Female patients and young patients are affected to a greater extent.
authors.affiliation: Department of Dermatology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, USA.
authors.forename: Joel M
authors.initials: JM
authors.lastname: Gelfand
authors.forename: Steven R
authors.initials: SR
authors.lastname: Feldman
authors.forename: Robert S
authors.initials: RS
authors.lastname: Stern
authors.forename: John
authors.initials: J
authors.lastname: Thomas
authors.forename: Tara
authors.initials: T
authors.lastname: Rolstad
authors.forename: David J
authors.initials: DJ
authors.lastname: Margolis
mesh_terms: D000367:Age Factors; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000523:psychology*; D011788:Quality of Life; D012720:Severity of Illness Index; D012737:Sex Factors; D011795:Surveys and Questionnaires; D014481:United States