Many P-element insertions affect wing shape in Drosophila melanogaster.
A screen of random, autosomal, homozygous-viable P-element insertions in D. melanogaster found small effects on wing shape in 11 of 50 lines. The effects were due to single insertions and remained stable and significant for over 5 years, in repeated, high-resolution measurements. All 11 insertions were within or near protein-coding transcription units, none of which were previously known to affect wing shape. Many sites in the genome can affect wing shape.
Weber
Kenneth
K
Department of Biological Sciences, University of Southern Maine, Portland, 04104-9300, USA. keweber@usm.maine.edu
Johnson
Nancy
N
Champlin
David
D
Patty
April
A
D000818:Animals; D001483:Base Sequence; D017931:DNA Primers; D004251:DNA Transposable Elements; D004331:Drosophila melanogaster / Q000196:embryology* / Q000235:genetics*; D010957:Plasmids; D015183:Restriction Mapping; D014921:Wings, Animal / Q000033:anatomy & histology*
D017931:DNA Primers; D004251:DNA Transposable Elements