Influence of time-delayed feedback in the firing pattern of thermally sensitive neurons.
We explore the dynamics of a Hodgkin-Huxley-type model for thermally sensitive neurons that exhibit intrinsic oscillatory activity. The model is modified to include a feedback loop that is represented by two parameters: the synaptic strength and the transmission delay time. We analyze the dynamics of the neuron depending on the temperature, the synaptic strength, and the delay time. We find parameter regions where the effect of the recurrent connexion is excitatory, inducing spikes or trains of spikes, and regions where it is inhibitory, reducing or eliminating completely the spiking behavior. We characterize the complex interplay of the intrinsic dynamics of the neuron with the recurrent feedback input and a noisy input.
Sainz-Trapága
M
M
Departamento de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.
Masoller
C
C
Braun
H A
HA
Huber
M T
MT
D000200:Action Potentials / Q000502:physiology*; D000222:Adaptation, Physiological / Q000502:physiology; D000818:Animals; D001683:Biological Clocks / Q000502:physiology*; D003198:Computer Simulation; D005246:Feedback / Q000502:physiology*; D006801:Humans; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology*; D013696:Temperature; D013823:Thermoreceptors / Q000502:physiology*; D013997:Time Factors