title: An LEA group 3 family member is involved in survival of C. elegans during exposure to stress.
abstract: In order to establish a functional role for late embryogenesis abundant (LEA) proteins in response to stress conditions in Caenorhabditis elegans, we silenced the expression of an LEA (Ce-lea-1) gene and determined the survival of worms under stress conditions. Ce-lea-1 transcription was induced during dehydration of C. elegans dauer juveniles. Following partial silencing of Ce-lea-1 transcription, we demonstrated a specific and significant reduction in worm survival during induction of desiccation, osmotic and heat stress. Together, these results establish a functional role for Ce-lea-1 in stress survival of C. elegans and suggest that Ce-lea-1 may function as a component that is common to the responses to the examined stress conditions.
authors.affiliation: Department of Nematology, ARO, The Volcani Center, Bet Dagan 50250, Israel.
authors.forename: Tali Z
authors.initials: TZ
authors.lastname: Gal
authors.forename: Itamar
authors.initials: I
authors.lastname: Glazer
authors.forename: Hinanit
authors.initials: H
authors.lastname: Koltai
mesh_terms: D000818:Animals; D001483:Base Sequence; D017173:Caenorhabditis elegans / Q000502:physiology*; D029742:Caenorhabditis elegans Proteins / Q000235:genetics / Q000502:physiology*; D017931:DNA Primers; D003681:Dehydration / Q000503:physiopathology*; D020868:Gene Silencing; D018882:Heat Stress Disorders; D009997:Osmotic Pressure; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014158:Transcription, Genetic
chemical_list: D029742:Caenorhabditis elegans Proteins; D017931:DNA Primers