title: The genomics of malaria infection.
abstract: Malaria research is now dominated by information flowing from the genome sequencing projects and the associated transcriptome- and proteome-mapping projects. As more species are sequenced, comparative and phylogenetic comparisons are improving the quality of gene finding, and are providing various approaches to the identification of genes important to parasite biology and the pathogenesis of disease. We are still in the early days of exploiting these data in a systematic way and the sheer volume of data presents daunting challenges. This article reviews the progress in using this genomic information and discusses opportunities for other approaches.
authors.affiliation: Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia. ross.coppel@med.monash.edu.au
authors.forename: Ross L
authors.initials: RL
authors.lastname: Coppel
authors.forename: David S
authors.initials: DS
authors.lastname: Roos
authors.forename: Zbynek
authors.initials: Z
authors.lastname: Bozdech
mesh_terms: D000818:Animals; D016054:DNA, Protozoan / Q000235:genetics; D018503:Genome, Protozoan; D023281:Genomics / Q000379:methods; D006801:Humans; D016778:Malaria, Falciparum / Q000469:parasitology*; D051379:Mice; D010963:Plasmodium falciparum / Q000235:genetics* / Q000502:physiology; D015800:Protozoan Proteins; D014158:Transcription, Genetic
chemical_list: D016054:DNA, Protozoan; D015800:Protozoan Proteins