Mycobacterium avium subsp. paratuberculosis strains isolated from Crohn's disease patients and animal species exhibit similar polymorphic locus patterns.
Analysis of short sequence repeats of Mycobacterium avium subsp. paratuberculosis isolated from Crohn's disease patients identified two alleles, both of which clustered with strains derived from animals with Johne's disease. Identification of a limited number of genotypes among human strains implies the existence of human disease-associated genotypes and strain sharing with animals.
Ghadiali
Alifiya H
AH
Food Animal Health Research Program, Ohio Agricultural Research Development Center, the Ohio State University, Wooster, Ohio 44691, USA.
Strother
Megan
M
Naser
Saleh A
SA
Manning
Elizabeth J B
EJ
Sreevatsan
Srinand
S
D000483:Alleles; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology; D003424:Crohn Disease / Q000382:microbiology*; D004269:DNA, Bacterial / Q000032:analysis; D015511:Goat Diseases / Q000382:microbiology; D006041:Goats; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics*; D016927:Mycobacterium avium subsp. paratuberculosis / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D010283:Paratuberculosis / Q000382:microbiology*; D011110:Polymorphism, Genetic; D012756:Sheep; D012757:Sheep Diseases / Q000382:microbiology
D004269:DNA, Bacterial