Role of antiplatelet therapy in cardiovascular disease II: Ischemic stroke.
The etiology of cerebrovascular disease is heterogeneous, with the majority of strokes being of ischemic origin. Transient ischemic attack is now considered to be an important precursor and long-term risk factor for ischemic stroke. Given the lack of acute therapies for ischemic stroke, current treatments focus on secondary prevention through risk-factor management, pharmacotherapy and interventional approaches. As illustrated in this paper, antiplatelet agents (e.g. clopidogrel, aspirin, dipyridamole) are the cornerstone of therapy for prevention of recurrent ischemic stroke.
Cavendish
Jeffrey J
JJ
Department of Cardiology, Naval Medical Center, San Diego, CA 92134, USA. JJCavendish@nmcsd.med.navy.mil
Cramer
Steven C
SC
Graham
Glenn D
GD
D000328:Adult; D000368:Aged; D002545:Brain Ischemia / Q000188:drug therapy* / Q000517:prevention & control; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D012008:Recurrence; D020521:Stroke / Q000188:drug therapy* / Q000517:prevention & control
D010975:Platelet Aggregation Inhibitors