title: Inhalation of nitric oxide in the treatment of severe acute respiratory syndrome: a rescue trial in Beijing.
abstract: Inhalation of nitric oxide (NO) improved arterial oxygenation and enabled the reduction of inspired oxygen therapy and airway pressure support in patients with severe acute respiratory syndrome (SARS). In addition, chest radiography showed decreased spread or density of lung infiltrates, and the physiological effects remained after termination of inhaled NO therapy. These findings suggest not only a pulmonary vasodilator effect of inhaled NO, but also an effect on SARS.
authors.affiliation: Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.
authors.forename: Luni
authors.initials: L
authors.lastname: Chen
authors.forename: Peng
authors.initials: P
authors.lastname: Liu
authors.forename: He
authors.initials: H
authors.lastname: Gao
authors.forename: Bing
authors.initials: B
authors.lastname: Sun
authors.forename: Desheng
authors.initials: D
authors.lastname: Chao
authors.forename: Fei
authors.initials: F
authors.lastname: Wang
authors.forename: Yuanjue
authors.initials: Y
authors.lastname: Zhu
authors.forename: Göran
authors.initials: G
authors.lastname: Hedenstierna
authors.forename: Chen G
authors.initials: CG
authors.lastname: Wang
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D002681:China; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009569:Nitric Oxide / Q000008:administration & dosage*; D045169:Severe Acute Respiratory Syndrome / Q000188:drug therapy*
chemical_list: D009569:Nitric Oxide