New reactions in water: metal-free conversion of alcohols and ketones into alpha-iodoketones.
Using water as the reaction medium, ketones can be transformed into alpha-iodoketones upon treatment with sodium iodide, hydrogen peroxide and an acid; interestingly, alpha-iodoketones can be also obtained from secondary alcohols through a metal-free tandem oxidation-iodination approach.
Barluenga
José
J
Instituto de Química Organometálica Enrique Moles, Universidad de Oviedo, Oviedo, 33006, Spain. barluenga@uniovi.es
Marco-Arias
María
M
González-Bobes
Francisco
F
Ballesteros
Alfredo
A
González
José M
JM