Endometrial biopsy: a test whose time has come and gone.
To document ovulation in an infertility investigation, a timed endometrial biopsy is painful, expensive, invasive, requires precise cycle timing for proper interpretation, and cannot independently distinguish between fertile and infertile women. Urinary LH kit testing has a significant false-positive rate (approximately 7.6%). A midluteal serum progesterone is a much simpler method that compares favorably with either endometrial biopsy or LH kit testing.
Haney
Arthur F
AF
The Chicago Lying-in Hospital, Department of Obstetrics and Gynecology, The University of Chicago, Chicago, Illinois 60637, USA. ahaney@babies.bsd.uchicago.edu
D001706:Biopsy; D004717:Endometrium / Q000473:pathology*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000473:pathology*; D018456:Reproductive Medicine / Q000639:trends*