title: Irradiating the groin nodes without breaking a leg: a comparison of techniques for groin node irradiation.
abstract: The purpose of this study was to determine the optimal technique for delivering postoperative radiotherapy for vulvar cancer and other tumors requiring treatment of the inguinal nodes. This project compared tumor coverage and normal tissue sparing for the 5 main radiotherapy techniques that are used to treat vulvar cancer. The intensity-modulated radiation therapy (IMRT) plan was undesirable because it resulted in an excessive dose to portions of the central pelvic structures. The photon thunderbird with skin match was unacceptable because it underdosed a portion of the groin region. The electron thunderbird was ideal for thin patients but was not applicable for most patients because of excessive dose to the skin and subcutaneous tissues. The photon through-and-through and the photon thunderbird with deep match were acceptable in most situations. In thin patients, where the depth of the inguinal vessels is less than 3 cm, the electron thunderbird is the technique of choice. In the average-sized patient, both the photon through-and-through and the photon thunderbird with deep match are reasonable options. The available literature suggests that the risk of femoral neck fracture or necrosis of the femoral head is approximately 11% at 5 years using the photon through-and-through technique. In our opinion, this is an acceptable price to pay for reliable node coverage, setup simplicity, and zero risk of overdose at field junctions.
authors.affiliation: Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL 32610-0385, USA.
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Gilroy
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Amdur
authors.forename: Debbie A
authors.initials: DA
authors.lastname: Louis
authors.forename: Jonathan G
authors.initials: JG
authors.lastname: Li
authors.forename: William M
authors.initials: WM
authors.lastname: Mendenhall
mesh_terms: D005260:Female; D005270:Femur Head; D005272:Femur Neck; D006119:Groin; D006801:Humans; D008198:Lymph Nodes; D015182:Lymphatic Irradiation / Q000379:methods*; D010388:Pelvis; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D012867:Skin; D040521:Subcutaneous Tissue; D014846:Vulvar Neoplasms / Q000532:radiotherapy*