title: Histamine H3 receptor agonists.
abstract: The SAR of H3 ligands has been difficult to evaluate because of species differences, multiple isoforms and constitutive activity, among other complicating factors. A review is given of the sometimes-conflicting affinity, activity and efficacy data of H3 agonists that has been described in literature to date.
authors.affiliation: De Novo Pharmaceuticals, Compass House, Vision Park Histon, Cambridge, UK. ideesch@few.vu.nl
authors.forename: I J P
authors.initials: IJ
authors.lastname: De Esch
authors.forename: K J
authors.initials: KJ
authors.lastname: Belzar
mesh_terms: D000818:Animals; D017442:Histamine Agonists / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D008024:Ligands; D018100:Receptors, Histamine H3 / Q000378:metabolism*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D017442:Histamine Agonists; D008024:Ligands; D018100:Receptors, Histamine H3