title: A novel drug target in Alzheimer's disease.
authors.affiliation: Department of Epidemiology and Biostatistics, Erasmus Medical Centre, 3000 DR Rotterdam, Netherlands. m.bornebroek@erasmusmc.nl
authors.forename: Marjolijn
authors.initials: M
authors.lastname: Bornebroek
authors.forename: Samir
authors.initials: S
authors.lastname: Kumar-Singh
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000188:drug therapy* / Q000378:metabolism; D053829:Amyloid Precursor Protein Secretases; D016564:Amyloid beta-Protein Precursor / Q000378:metabolism; D000818:Animals; D016282:Aspartic Acid Endopeptidases / Q000378:metabolism; D002352:Carrier Proteins / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D009185:Myelin Proteins; D009419:Nerve Tissue Proteins / Q000378:metabolism; D000070798:Nogo Proteins
chemical_list: D016564:Amyloid beta-Protein Precursor; D002352:Carrier Proteins; D047908:Intracellular Signaling Peptides and Proteins; D008565:Membrane Proteins; D009185:Myelin Proteins; D009419:Nerve Tissue Proteins; D000070798:Nogo Proteins; C476198:RTN3 protein, human; C000603199:RTN4 protein, human; C000603201:Rtn4 protein, mouse; D053829:Amyloid Precursor Protein Secretases; D010450:Endopeptidases; D016282:Aspartic Acid Endopeptidases; C509284:BACE2 protein, human; C509280:BACE1 protein, human; C509282:Bace1 protein, mouse