[Effect of integrated traditional Chinese and Western medicine therapy on progression of acute renal failure in patients with chronic renal insufficiency: a short-term clinical study].
OBJECTIVE
To evaluate the effect of integrated traditional Chinese and Western medicine therapy on the progression of acute renal failure in patients with chronic renal insufficiency.


METHODS
Thirty-two patients with chronic renal insufficiency developed acute renal failure recently were treated with Chinese herbs and western drugs intravenously and clysterizing of Chinese herbs liquid for 30 minutes, and the treatment course was 14 days. Assessment of liver and renal function, blood routine, electrolytes and endogenous creatinine clearance rate (Ccr) was performed before and 2 weeks after the treatment.


RESULTS
The levels of hemoglobin (HB), white blood cell count (WBC) and serum electrolytes showed no significant changes after the treatment. The levels of blood urea nitrogen (BUN) and serum creatinine (SCr) decreased, while the level of Ccr increased significantly (P<0.05) after the treatment. The total effective rate was 65.6%.


CONCLUSIONS
The integrated traditional Chinese and Western medicine therapy can effectively delay the deterioration of renal function in patients with chronic renal insufficiency accompanied by acute renal failure.
Fu
Peng
P
Department of Nephrology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China. fupeng66@citiz.net
Yu
Guang
G
Huang
Xue-Qiang
XQ
Xu
Jing
J
Mei
Xiao-Bin
XB
Wu
Hao
H
Yuan
Wei-Jie
WJ
D058186:Acute Kidney Injury / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001806:Blood Urea Nitrogen; D003404:Creatinine / Q000097:blood / Q000378:metabolism; D018450:Disease Progression; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000188:drug therapy*; D007677:Kidney Function Tests; D008111:Liver Function Tests; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D028321:Plant Preparations; D011188:Potassium / Q000097:blood / Q000378:metabolism; D012189:Retrospective Studies; D012964:Sodium / Q000097:blood / Q000378:metabolism; D016896:Treatment Outcome
D004365:Drugs, Chinese Herbal; D010936:Plant Extracts; D028321:Plant Preparations; D012964:Sodium; D003404:Creatinine; D011188:Potassium