title: Multiple cutaneous reticulohistiocytomas in a patient with rheumatoid arthritis.
abstract: A 64-year-old woman with a long-standing peripheral symmetric polyarthritis with positive rheumatoid serology was evaluated for multiple asymptotic papulonodules of fingers, mentum, lower lip, ears, and eyelids. Histopathologic examination showed a dermal infiltrate composed of histiocytes, multinucleate giant cells with ground-glass cytoplasm, and lymphocytes, suggestive of reticulohistiocytoma. The possibilities of multicentric reticulohistiocytosis with positive rheumatoid serology or coexistence of multiple cutaneous reticulohistiocytomas and rheumatoid arthritis are discussed.
authors.affiliation: Department of Dermatology, University Hospital, Coimbra, Portugal. ricardojvieira@aeiou.pt
authors.forename: Ricardo
authors.initials: R
authors.lastname: Vieira
authors.forename: Margarida Robalo
authors.initials: MR
authors.lastname: Cordeiro
authors.forename: Angelina
authors.initials: A
authors.lastname: Mariano
authors.forename: Jose Pedro
authors.initials: JP
authors.lastname: Reis
authors.forename: Oscar
authors.initials: O
authors.lastname: Tellechea
authors.forename: Americo
authors.initials: A
authors.lastname: Figueiredo
mesh_terms: D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000473:pathology*; D005260:Female; D015616:Histiocytosis, Non-Langerhans-Cell / Q000150:complications* / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D012871:Skin Diseases / Q000150:complications* / Q000473:pathology*