title: Immunomodulators for skin cancer.
abstract: Therapeutic interventions to augment tumor antigenicity or increase the host's immune response against cancer cells include recombinant cytokines, immune modulators, vaccination with tumor antigens, T cell-based immunotherapy, and gene therapy. We describe the current role of the immunomodulators (up-regulators of the immune response) in the therapy of skin cancer (non melanoma skin cancer, melanoma, lymphoma, Kaposi sarcoma, and extramammary Paget's disease).
authors.affiliation: Department of Dermatology and Cutaneous Surgery University of Miami-School of Medicine, FL, USA.
authors.forename: Adriana M
authors.initials: AM
authors.lastname: Villa
authors.forename: Brian
authors.initials: B
authors.lastname: Berman
mesh_terms: D000634:Aminoquinolines / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001913:Bowen's Disease / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D006801:Humans; D000077271:Imiquimod; D007155:Immunologic Factors / Q000627:therapeutic use*; D007372:Interferons / Q000627:therapeutic use*; D008223:Lymphoma / Q000188:drug therapy*; D008545:Melanoma / Q000188:drug therapy*; D010145:Paget Disease, Extramammary / Q000188:drug therapy*; D012514:Sarcoma, Kaposi / Q000188:drug therapy*; D012878:Skin Neoplasms / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D007155:Immunologic Factors; D007372:Interferons; D000077271:Imiquimod