Thromboembolic events and haematological diseases: a case of stroke as clinical onset of a paroxysmal nocturnal haemoglobinuria.
Some haematological diseases are associated to an increased risk of thromboembolic events. We report a case of paroxysmal nocturnal haemoglobinuria (PNH) in which a cerebrovascular event represented the first clinical manifestation of disease. PNH is associated to thromboembolic events, generally of venous districts often involving unusual locations such as mesenteric vessels, sagittal veins, inferior vena cava and renal veins.To our knowledge arterial thrombotic episodes are rare and the involvement of arterial cerebral vessels is exceptional. Then, our case points out the importance of investigating about haematological disorders in all patients presenting with a stroke, in which the common predisposing conditions are excluded.
Granata
Gianluca
G
Internal Medicine of Second University of Naples, Naples, Italy. calimero.pocali@libero.it.
Izzo
Tiziana
T
Di Micco
Pierpaolo
P
Bonamassa
Barbara
B
Castaldo
Giampiero
G
Viggiano
Vito Giuseppe
VG
Picillo
Ugo
U
Castaldo
Giuseppe
G
Niglio
Alferio
A