title: Chronic renal failure in an English bull terrier with polycystic kidney disease.
abstract: An entire female English bull terrier, aged five years and one month, was diagnosed with polycystic kidney disease by renal ultrasonography. It had thickening and abnormal motion of the mitral valve on 2D and M mode echocardiography, and left ventricular outflow tract obstruction, characterised by turbulence in the left ventricular outflow tract and elevated aortic blood flow velocity, detected by colour flow and spectral Doppler echocardiography, respectively. Two years later, haematology, serum biochemistry and urinalysis data suggested the presence of compensated renal failure. The dog was euthanased at 10 years and eight months of age, with haematology, serum biochemistry and urinalysis data Indicating decompensated chronic renal failure. Postmortem examination confirmed polycystic kidney disease, chronic renal disease, mitral and aortic valvular myxomatous degeneration, and mixed mammary neoplasia. This case demonstrates that bull terriers with polycystic kidney disease may develop associated chronic renal failure.
authors.affiliation: School of Veterinary Science, The University of Queensland, St Lucia, Queensland, Australia.
authors.forename: C A
authors.initials: CA
authors.lastname: O'Leary
authors.forename: S
authors.initials: S
authors.lastname: Turner
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity; D004283:Dog Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000209:etiology; D004285:Dogs; D018618:Echocardiography, Doppler, Color / Q000379:methods / Q000662:veterinary; D017809:Fatal Outcome; D005260:Female; D007668:Kidney / Q000000981:diagnostic imaging; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000662:veterinary*; D007690:Polycystic Kidney Diseases / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000662:veterinary*; D014694:Ventricular Outflow Obstruction / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000662:veterinary