title: Etiology of azoospermia in 100 consecutive nonvasectomized men.
abstract: History was taken systematically for 100 azoospermic, nonvasectomized men referred consecutively to a Danish fertility clinic. The men were examined by ultrasound, and their blood samples were analyzed for karyotype, Y microdeletions, and cystic fibrosis transmembrane conductance regulator gene mutations. In 29% of patients, the condition could be explained by genetic abnormalities; in 22%, by diseases or external influence; and in 27%, by former cryptorchidism. The azoospermic condition remained unexplained in only 22%.
authors.affiliation: The Fertility Clinic, Braedstrup Hospital, Braedstrup, Denmark. jfe@bs.vejleamt.dk
authors.forename: Jens
authors.initials: J
authors.lastname: Fedder
authors.forename: Dorthe
authors.initials: D
authors.lastname: Crüger
authors.forename: Birthe
authors.initials: B
authors.lastname: Oestergaard
authors.forename: Gert Bruun
authors.initials: GB
authors.lastname: Petersen
mesh_terms: D003456:Cryptorchidism / Q000150:complications; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics; D006801:Humans; D008297:Male; D009154:Mutation; D009845:Oligospermia / Q000000981:diagnostic imaging / Q000209:etiology* / Q000235:genetics / Q000473:pathology; D014463:Ultrasonography; D014649:Vas Deferens / Q000002:abnormalities
chemical_list: C505032:CFTR protein, human; D019005:Cystic Fibrosis Transmembrane Conductance Regulator