The relationship between iron status and thyroid hormones in adolescents living in an iodine deficient area.
BACKGROUND
Iron may be only one of many nutritional factors that influence thyroid hormone metabolism in iodine-deficient areas.


OBJECTIVE
To evaluate the effect of iron status on thyroid hormone profile in adolescents living in a mild iodine-deficient area in Turkey.


METHODS
Three hundred and thirty school-aged children with mean age 14 years were examined.


METHODS
Free triiodothyronine, free tetraiodothyronine and thyrotropin levels were analyzed by chemiluminescent enzyme immunoassay. Hemoglobin and mean corpuscular volume were measured with a Hemocounter. Iron and total iron binding capacity concentration were determined by colorimetric photometric methods. Ferritin level was determined by immunoturbidimetry.


RESULTS
Thyroid hormone levels of the children with anemia were not significantly different compared to children without anemia. No significant correlation was found between thyroid hormones and iron status.


CONCLUSIONS
The thyroid hormone profile was not significantly affected in this area. This survey showed no correlation between iron status and thyroid hormone levels.
Yavuz
Ozlem
O
Department of Biochemistry, Düzce School of Medicine, Abant Izzet Baysal University, Düzce, Turkey. o_yavuz@yahoo.com
Yavuz
Taner
T
Kahraman
Cemil
C
Yeşildal
Nuray
N
Bundak
Ruveyde
R
D000293:Adolescent; D000740:Anemia / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D002648:Child; D015897:Comorbidity; D019353:Endemic Diseases / Q000706:statistics & numerical data; D005260:Female; D006043:Goiter, Endemic / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D006454:Hemoglobins; D006801:Humans; D015994:Incidence; D007455:Iodine / Q000172:deficiency; D007501:Iron / Q000097:blood*; D008297:Male; D012016:Reference Values; D013960:Thyroid Function Tests; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood*; D014284:Triiodothyronine / Q000097:blood*; D014421:Turkey / Q000453:epidemiology
D006454:Hemoglobins; D014284:Triiodothyronine; D013972:Thyrotropin; D007455:Iodine; D007501:Iron; D013974:Thyroxine