Kinetic control in noncovalent synthesis: regioselective ligand exchange into a hydrogen bonded assembly.
This paper illustrates the use of a kinetically controlled exchange reaction to effect regioselective modification of a hydrogen-bonded assembly. Both the bound anion and cation can control the exchange of ligand into the different layers of a synthetic G-quadruplex.
Davis
Jeffery T
JT
Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, USA. jd140@umail.umd.edu
Kaucher
Mark S
MS
Kotch
Frank W
FW
Iezzi
Maura A
MA
Clover
Bryna C
BC
Mullaugh
Katherine M
KM