title: A divIVA null mutant of Staphylococcus aureus undergoes normal cell division.
abstract: DivIVA is involved in placement of the division septum and chromosome segregation in Bacillus subtilis and it plays important roles in cell division or morphogenesis in diverse Gram-positive bacteria. In Staphylococcus aureus, DivIVA is localized at the division septum, but it does not colocalize with the chromosomal origin of replication, as labeled with SpoOJ protein. Unexpectedly, a divIVA null mutant is not impaired in growth, nor is it affected in chromosome segregation or cell morphology.
authors.affiliation: Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.
authors.forename: Mariana G
authors.initials: MG
authors.lastname: Pinho
authors.forename: Jeff
authors.initials: J
authors.lastname: Errington
mesh_terms: D001426:Bacterial Proteins / Q000032:analysis / Q000235:genetics* / Q000502:physiology*; D018797:Cell Cycle Proteins / Q000032:analysis / Q000235:genetics* / Q000502:physiology*; D002455:Cell Division / Q000235:genetics; D020090:Chromosome Segregation; D004268:DNA-Binding Proteins / Q000032:analysis; D017353:Gene Deletion; D013211:Staphylococcus aureus / Q000166:cytology / Q000235:genetics* / Q000254:growth & development*
chemical_list: D001426:Bacterial Proteins; D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; C104636:DivIVA protein, bacteria