Application of methods of identifying receptor binding models and analysis of parameters.
BACKGROUND
Possible methods for distinguishing receptor binding models and analysing their parameters are considered.


CONCLUSIONS
The conjugate gradients method is shown to be optimal for solving problems of the kind considered. Convergence with experimental data is rapidly achieved with the appropriate model but not with alternative models.


CONCLUSIONS
Lack of convergence using the conjugate gradients method can be taken to indicate inconsistency between the receptor binding model and the experimental data. Thus, the conjugate gradients method can be used to distinguish among receptor binding models.
Gurevich
Konstantin G
KG
UNESCO Chair in healthy life for sustainable development, Moscow State Dentistry Medical University (MSDMU), Delegatskaya street 20/1, 127473, Moscow, Russian Federation, Russia. kgurevich@newmail.ru
D006801:Humans; D008024:Ligands; D008954:Models, Biological; D011956:Receptors, Cell Surface / Q000378:metabolism*
D008024:Ligands; D011956:Receptors, Cell Surface