title: Nicotine use in schizophrenia and disinhibition.
abstract: The role of personality in nicotine use has been little studied in patients with schizophrenia. The objectives of the present study were to compare impulsivity, sensation seeking and anhedonia in a group of schizophrenic patients with and without current cigarette smoking. One hundred patients with schizophrenia or schizoaffective disorder (DSM-III-R criteria) were assessed with the Positive and Negative Syndrome Scale, the Fagerström Scale, the Barratt Impulsivity Scale, the Zuckerman Seeking Sensation Scale, and the Chapman Physical Anhedonia Scale. Among these patients, 67% were current smokers. The mean scores for sensation seeking were higher in the group of smokers than in the group of nonsmokers. The differences were found exclusively with the "disinhibition" subscale. No significant difference was found for impulsivity and physical anhedonia mean scores. The scores on the Sensation Seeking Scale were especially low in nonsmokers. Cigarette smoking could influence disinhibition and possibly help to normalize inhibition in schizophrenic patients.
authors.affiliation: Service de Psychiatrie, BP 27, Centre Hospitalier, F91401 Orsay, France. alaindervaux@wanadoo.fr
authors.forename: Alain
authors.initials: A
authors.lastname: Dervaux
authors.forename: Franck J
authors.initials: FJ
authors.lastname: Baylé
authors.forename: Xavier
authors.initials: X
authors.lastname: Laqueille
authors.forename: Marie-Chantal
authors.initials: MC
authors.lastname: Bourdel
authors.forename: Michèle-Hélène
authors.initials: MH
authors.lastname: Le Borgne
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Olié
authors.forename: Marie-Odile
authors.initials: MO
authors.lastname: Krebs
mesh_terms: D000328:Adult; D000342:Affective Symptoms / Q000175:diagnosis / Q000453:epidemiology; D001143:Arousal; D015897:Comorbidity; D005260:Female; D006801:Humans; D007175:Impulsive Behavior / Q000175:diagnosis / Q000453:epidemiology; D007266:Inhibition, Psychological; D008297:Male; D008875:Middle Aged; D010555:Personality Inventory; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D012309:Risk-Taking; D012559:Schizophrenia / Q000175:diagnosis / Q000453:epidemiology*; D012565:Schizophrenic Psychology; D012907:Smoking / Q000453:epidemiology* / Q000523:psychology; D013223:Statistics as Topic