title: Nasal chondromesenchymal hamartoma: report of a case and review of the literature.
abstract: The sinonasal region is the site of several hamartomatous lesions, the majority of which are mesenchymal, with vascular hamartomas predominating. The occurrence of hamartomas in the nasal cavity of infants and children is especially rare. Nasal chondromesenchymal hamartoma (NCMH) is a rare lesion of the intranasal sinuses generally diagnosed in the newborn period, with the eldest reported patient presenting at 16 years of age. This neoplasm is composed of mesenchymal-stromal and chondroid tissue in varying proportions. It is felt to be analogous to the mesenchymal hamartoma of the chest wall, a lesion of similar histology generally involving the ribs and chest wall of neonates. To the best of our knowledge, only 14 cases of NCMH have been reported to date. We report a case of NCMH in an 11-year-old boy.
authors.affiliation: Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
authors.forename: Elizabeth S
authors.initials: ES
authors.lastname: Norman
authors.forename: Simon
authors.initials: S
authors.lastname: Bergman
authors.forename: Jacqueline K
authors.initials: JK
authors.lastname: Trupiano
mesh_terms: D002356:Cartilage / Q000378:metabolism / Q000473:pathology*; D002648:Child; D006222:Hamartoma / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008648:Mesoderm / Q000378:metabolism / Q000473:pathology*; D010254:Paranasal Sinus Diseases / Q000378:metabolism / Q000473:pathology*