Study of lubricant-induced changes in chronic snorers (SLICCS).
OBJECTIVE
The efficacy of many of the noninvasive treatments for snoring has not been evaluated in controlled trials. This paper seeks to evaluate the efficacy of an oil-based spray in the treatment of snoring, in a double-blinded, placebo-controlled, crossover trial using objective acoustic analysis and subjective questionnaires.


METHODS
Participants were randomized to use both oil-based oral spray (treatment) and water-based oral spray (placebo) during a two-night in-home study period. Questionnaires were completed by participant and bed-partner in addition to audio-tape recordings which were analyzed for frequency, duration, and mean energy of snoring.


RESULTS
Greatest snoring rate demonstrated 30% = benefit; 40% = no change; 30% = adverse effect (n = 20). Percent time snoring yielded: 30% benefit; 15% no change; 55% adverse effect (n = 20). Study data results for mean energy were (n = 12): benefit = 17%, no change = 33%, adverse effect = 50%. Bed-partner observations (n = 17) demonstrated 37% = benefit; 38% = no change; 25% = adverse effect.


CONCLUSIONS
Objective and subjective evaluation of the performance of the oil-based Snoreless spray in comparison to placebo demonstrated a lack of efficacy in snoring reduction.
Wijewickrama
Rohan C
RC
Wake Forest University School of Medicine, Winston-Salem, NC 25157, USA.
Blalock
David
D
Mims
James W
JW
D000162:Acoustics / Q000295:instrumentation; D000287:Administration, Topical; D000328:Adult; D002908:Chronic Disease; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008153:Lubrication; D008297:Male; D008875:Middle Aged; D009821:Oils / Q000008:administration & dosage*; D012913:Snoring / Q000175:diagnosis / Q000188:drug therapy*; D013637:Tape Recording; D016896:Treatment Outcome
D009821:Oils