title: Validity of primary care patient self-report of abnormal (but not cancer) prostate biopsy results.
abstract: OBJECTIVE
  We assessed the validity of patient self-report of abnormal (but not cancer) prostate biopsy results, ie, atypical cells or prostatic intraepithelial neoplasia.
  
  
  METHODS
  We compared survey responses and pathology records for 156 men from a multicenter, prospective cohort study, which was designed to evaluate the impact of a suspicious prostate cancer screening test followed by benign prostate biopsy.
  
  
  RESULTS
  Of the 156 subjects 45 (29%) reported having had atypical cells or prostatic intraepithelial neoplasia and 38 (24%) had a pathology report with atypia or prostate intraepithelial neoplasia. The sensitivity of the self-report was 87%, specificity was 90%, positive predictive value was 73% and negative predictive value was 95%. The kappa statistic was 0.7.
  
  
  CONCLUSIONS
  Men in this study reported this complex result accurately. However, it was concerning that 5 men (13%) appeared unaware of an abnormal prostate biopsy result, especially given the substantial residual risk of prostate cancer conferred by this result.
authors.affiliation: General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. mmcnaughtoncollins@partners.org
authors.forename: Mary
authors.initials: M
authors.lastname: McNaughton-Collins
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Barry
authors.forename: Jean-Francois
authors.initials: JF
authors.lastname: Caubet
authors.forename: David W
authors.initials: DW
authors.lastname: Bates
authors.forename: Jeong Min
authors.initials: JM
authors.lastname: Lee
authors.forename: Alison
authors.initials: A
authors.lastname: Hauser
authors.forename: Floyd J
authors.initials: FJ
authors.lastname: Fowler
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D015331:Cohort Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology; D015203:Reproducibility of Results; D012650:Self Disclosure; D011795:Surveys and Questionnaires