Celiac disease during pregnancy.
OBJECTIVE
One of my patients was diagnosed with celiac disease and maintains a strict gluten-free diet. Is her fetus at risk of neural tube defects because she does not get folic acid from bread and other flour-based foods?


CONCLUSIONS
A woman with celiac disease must supplement her diet with multivitamins, including folic acid. Most prenatal vitamins contain 0.8 to 0.9 mg of folic acid, double the amount recommended by Health Canada for prevention of neural tube defects. Without supplementation (eg, undiagnosed pregnancy), women with celiac disease might not take in enough folate to maintain protective levels.
Hancock
Rebecca
R
Motherisk Program, Hospital for Sick Children, Toronto, Ont.
Koren
Gideon
G
D002446:Celiac Disease / Q000150:complications* / Q000178:diet therapy* / Q000378:metabolism; D019587:Dietary Supplements; D005260:Female; D005492:Folic Acid / Q000008:administration & dosage / Q000378:metabolism; D005494:Folic Acid Deficiency / Q000209:etiology / Q000517:prevention & control; D005527:Food, Fortified; D006397:Hematinics / Q000008:administration & dosage; D006801:Humans; D009436:Neural Tube Defects / Q000209:etiology / Q000517:prevention & control; D011247:Pregnancy; D011248:Pregnancy Complications / Q000178:diet therapy* / Q000378:metabolism / Q000517:prevention & control
D006397:Hematinics; D005492:Folic Acid