Stereochemical control of the Passerini reaction.
A catalytic asymmetric Passerini reaction using tridentate indan (pybox) Cu(II) Lewis acid complex 4 with substrates capable of bidentate coordination has been achieved. The reaction occurs via ligand-accelerated catalysis.
Andreana
Peter R
PR
Howard Hughes Medical Institute, Center for Chemical Methodology and Library Development (CMLD-HU) & Broad Institute of Harvard and MIT, Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
Liu
Chang C
CC
Schreiber
Stuart L
SL
D002384:Catalysis; D007189:Indans / Q000737:chemistry*; D013237:Stereoisomerism
D007189:Indans; C093582:indan