[A case of disseminated tumor from cecal cancer with survival for over 5 years after twice surgical resection and systemic chemotherapy].
A 66-year-old man underwent a curative operation for cecal cancer on the 30th of November, 1998. Since his CEA level rose in January 2001, computed tomography (CT) revealed a tumor in the abdomen. He underwent a resection of this tumor and disseminated tumors that were diagnosed during the operation. He received systemic chemotherapy (5'-DFUR 600 mg 3x everyday, CPT-11 80 mg/body div every 2 weeks), but the CEA level rose again in August 2003. He was diagnosed with spleen metastasis and underwent splenectomy. The tumor disseminated in the left diaphragm was also resected. After that, he received systemic chemotherapy (5-FU 500 mg/body/week div, levofolinate calcium 250 mg/body/week i.v.) as an outpatient. Peritoneal carcinomatosis from colorectal cancer with distant metastasis, in general, has no indication for an operation. However, if dissemination is located after a sufficient observation period, its resection may be recommended.
Tamesa
Takao
T
Dept. of Surgery II, Yamaguchi University School of Medicine.
Watanabe
Yusaku
Y
Yoshimura
Kiyoshi
K
Mori
Naohide
N
Yamamoto
Shigeru
S
Hazama
Shoichi
S
Tangoku
Akira
A
Oka
Masaaki
M
D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D002272:Carcinoembryonic Antigen / Q000097:blood; D002430:Cecal Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D005467:Floxuridine / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D000077146:Irinotecan; D002955:Leucovorin / Q000008:administration & dosage; D008297:Male; D009366:Neoplasm Seeding; D010534:Peritoneal Neoplasms / Q000556:secondary* / Q000628:therapy*; D012086:Reoperation
D002272:Carcinoembryonic Antigen; D005467:Floxuridine; D000077146:Irinotecan; D002955:Leucovorin; D005472:Fluorouracil; C025034:doxifluridine; D002166:Camptothecin