Remote intrapulmonary spread of recurrent respiratory papillomatosis with malignant transformation.
Recurrent respiratory papillomatosis is the most common neoplasm of the larynx in childhood. Extension into lung parenchyma occurs in less than 1% of patients and has a low risk of malignant transformation. Treatment options for intrapulmonary spread have shown limited success. We describe a case of recurrent respiratory papillomatosis with extensive parenchymal involvement and adenosquamous carcinoma in a 14-year-old girl.
Katz
Sherri L
SL
Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
Das
Prabodh
P
Ngan
Bo-Yee
BY
Manson
David
D
Pappo
Alberto S
AS
Sweezey
Neil B
NB
Solomon
Melinda P
MP
D000293:Adolescent; D001707:Biopsy, Needle; D018196:Carcinoma, Adenosquamous / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D010212:Papilloma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed