title: An unexpected three-component condensation leading to amino- (3-oxo-2,3-dihydro-1H-isoindol-1-ylidene)- acetonitriles.
abstract: The reaction of 2-carboxybenzaldehyde with primary amines in the presence of cyanide leads to the formation of 2-substituted amino(3-oxo-2,3-dihydro-1H-isoindol-1-ylidene)acetonitriles. These compounds originate from the condensation of 2-carboxybenzaldehyde with the amine and two molecules of hydrogen cyanide and represent a novel class of isoindolinones.
authors.affiliation: Institut für Organische Chemie, Universität Mainz, Duesbergweg 10-14, 55128 Mainz, Germany. opatz@uni-mainz.de
authors.forename: Till
authors.initials: T
authors.lastname: Opatz
authors.forename: Dorota
authors.initials: D
authors.lastname: Ferenc