title: [Metachronous sinonasal squamous-cell carcinoma after pharyngolaryngectomy].
abstract: OBJECTIVE
  Three laryngectomized patients developed metachronous sinonasal squamous-cell carcinoma. We reviewed their files to search for clinical features useful for early diagnosis of this localization.
  
  
  METHODS
  Two of the patients, a textile worker and a food processing worker, had occupation exposure risk factors for sinonasal squamous-cell carcinoma. The anatomic modifications created by laryngectomy contributed to late diagnosis of the metachronous tumor at an advanced stage. Surgery was performed in all three patients. Local recurrence was observed at one year in two patients.
  
  
  CONCLUSIONS
  Sinonasal fibroscopy should be part of the surveillance scheme in laryngectomized patients to enable early diagnosis and treatment of metachronous tumors.
authors.affiliation: Service d'ORL et de CCF, CHU Bretonneau, 2 Bd Tonnellé, 37034 Tours, France. moriniere@med.univ-tours.fr
authors.forename: S
authors.initials: S
authors.lastname: Morinière
authors.forename: P
authors.initials: P
authors.lastname: Beutter
authors.forename: C
authors.initials: C
authors.lastname: Gendre
authors.forename: E
authors.initials: E
authors.lastname: Lescanne
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000556:secondary*; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods*; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology*; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods; D010255:Paranasal Sinus Neoplasms / Q000556:secondary*; D010610:Pharyngeal Neoplasms / Q000473:pathology* / Q000601:surgery*; D010614:Pharynx / Q000473:pathology* / Q000601:surgery*