title: Live attenuated influenza vaccine induces cross-reactive antibody responses in children against an a/Fujian/411/2002-like H3N2 antigenic variant strain.
abstract: Serum antibody titers against the A/Panama/2007/99(H3N2) and A/Fujian/411/2002(H3N2)-like viruses were determined in children 6-35 months of age who received either 1 dose of the inactivated influenza vaccine or the live attenuated influenza vaccine containing the A/Panama strain. Results indicated that the live vaccine induced higher antibody responses than the inactivated vaccine against the A/Panama and A/Fujian-like viruses.
authors.affiliation: MedImmune Vaccines, Mountain View, CA, USA.
authors.forename: Paul M
authors.initials: PM
authors.lastname: Mendelman
authors.forename: Ruth
authors.initials: R
authors.lastname: Rappaport
authors.forename: Iksung
authors.initials: I
authors.lastname: Cho
authors.forename: Stan
authors.initials: S
authors.lastname: Block
authors.forename: William
authors.initials: W
authors.lastname: Gruber
authors.forename: Marilyn
authors.initials: M
authors.lastname: August
authors.forename: Denise
authors.initials: D
authors.lastname: Dawson
authors.forename: Julie
authors.initials: J
authors.lastname: Cordova
authors.forename: George
authors.initials: G
authors.lastname: Kemble
authors.forename: Kutubuddin
authors.initials: K
authors.lastname: Mahmood
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Palladino
authors.forename: Min-Shi
authors.initials: MS
authors.lastname: Lee
authors.forename: Ahmad
authors.initials: A
authors.lastname: Razmpour
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Stoddard
authors.forename: Bruce D
authors.initials: BD
authors.lastname: Forrest
mesh_terms: D000367:Age Factors; D000914:Antibodies, Viral / Q000032:analysis / Q000276:immunology*; D000917:Antibody Formation / Q000276:immunology; D002675:Child, Preschool; D005260:Female; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007115:Immunization Schedule; D015994:Incidence; D007223:Infant; D053122:Influenza A Virus, H3N2 Subtype; D009980:Influenza A virus / Q000145:classification* / Q000276:immunology*; D007252:Influenza Vaccines / Q000008:administration & dosage* / Q000276:immunology; D007251:Influenza, Human / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control*; D008297:Male; D011336:Probability; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D012737:Sex Factors; D018709:Statistics, Nonparametric; D014481:United States / Q000453:epidemiology; D014611:Vaccination / Q000379:methods*; D014613:Vaccines, Attenuated / Q000008:administration & dosage / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D007252:Influenza Vaccines; D014613:Vaccines, Attenuated