title: Computerised patient-specific guidelines for management of common mental disorders in primary care: a randomised controlled trial.
abstract: BACKGROUND
  A large proportion of people with depression and anxiety go unrecognised by their general practitioner (GP). Case-finding does not appear to be effective on its own.
  
  
  OBJECTIVE
  To compare the effectiveness of case-finding followed by computer-generated patient-specific guidelines with usual care for the management of common mental disorders in primary care.
  
  
  METHODS
  Individual patient randomised controlled trial.
  
  
  METHODS
  Five general practices in Bristol and Cardiff.
  
  
  METHODS
  762 individuals aged >/= 16 years scoring >/= 12 on the Clinical Interview Schedule Revised were randomised. The experimental intervention required participants to complete a computerised psychosocial assessment that generated a report for the GP including patient-specific treatment recommendations. The control patients were treated as usual with access to locally agreed guidelines.
  
  
  RESULTS
  Participants' 12-item General Health Questionnaire (GHQ) score dropped irrespective of treatment allocation. The experimental group had a significantly lower GHQ score at 6 weeks, but not at 6 months. Recovery at 6 months was 3% greater among those receiving the experimental intervention (95% confidence interval [CI] = -4 to 10). Treatment was not significantly associated with quality of life or patient satisfaction.
  
  
  CONCLUSIONS
  Only small benefits are likely from using case-finding followed by patient-specific guidelines to improve clinical management of common mental disorders in primary care. However, depression and anxiety are important public health problems so the utility of such systems should be further investigated.
authors.affiliation: Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK.
authors.forename: Hollie V
authors.initials: HV
authors.lastname: Thomas
authors.forename: Glyn
authors.initials: G
authors.lastname: Lewis
authors.forename: Margaret
authors.initials: M
authors.lastname: Watson
authors.forename: Truda
authors.initials: T
authors.lastname: Bell
authors.forename: Ita
authors.initials: I
authors.lastname: Lyons
authors.forename: Keith
authors.initials: K
authors.lastname: Lloyd
authors.forename: Scott
authors.initials: S
authors.lastname: Weich
authors.forename: Deborah
authors.initials: D
authors.lastname: Sharp
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001008:Anxiety Disorders / Q000628:therapy; D003658:Decision Making, Computer-Assisted; D003866:Depressive Disorder / Q000628:therapy; D005194:Family Practice / Q000458:organization & administration*; D005500:Follow-Up Studies; D006801:Humans; D001523:Mental Disorders / Q000628:therapy*; D008875:Middle Aged; D017060:Patient Satisfaction; D017410:Practice Guidelines as Topic; D011788:Quality of Life; D016896:Treatment Outcome