title: Radiotherapy for breast cancer in patients undergoing breast reconstruction or augmentation.
abstract: Due to increasing indications for postmastectomy radiotherapy and a growing demand for breast reconstruction or augmentation, increasing numbers of patients are currently being exposed to both these treatments. In view of the wide range of available techniques for breast reconstruction, either prosthetic or autologous, and their various sequencing in relation to radiotherapy, physicians can be faced with numerous clinical situations requiring comprehensive knowledge of the topic. This review discusses physical, radiobiological and clinical aspects of combining breast reconstruction and radiotherapy. The available data indicate the feasibility of such combinations, although at the expense of increased risk of complications and less satisfactory cosmesis. Of the two methods of breast reconstruction: using autologous tissue or prosthesis, the former seems to provide better cosmesis and a lower risk of complications in conjunction with radiotherapy. To minimize the risk of unfavourable outcome, the techniques and timing of both breast reconstruction and radiotherapy should be given meticulous attention.
authors.affiliation: Department of Oncology and Radiotherapy, Medical University of Gdańsk, Debinki 7, 80-211 Gdańsk, Poland. elsenkus@amg.gda.pl
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Senkus-Konefka
authors.forename: Marzena
authors.initials: M
authors.lastname: Wełnicka-Jaśkiewicz
authors.forename: Janusz
authors.initials: J
authors.lastname: Jaśkiewicz
authors.forename: Jacek
authors.initials: J
authors.lastname: Jassem
mesh_terms: D019928:Breast Implantation; D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008408:Mastectomy; D015412:Mastectomy, Segmental; D011183:Postoperative Complications; D011878:Radiotherapy / Q000379:methods; D019651:Plastic Surgery Procedures; D013997:Time Factors