title: Fibrous pleural tumor with hypoglycemia: case study.
abstract: Many neoplastic tumors exhibit paraneoplastic syndromes manifested by endocrinopathy. This is particularly true of intrathoracic tumors such as lung cancers, thymomas, carcinoid tumors and mediastinal germ cell neoplasm. Fibrous tumors of the pleura are rare intrathoracic tumors, which are usually benign and often grow to huge size. A subset of these neoplasms present with the syndrome of hypoglycemia. Although first reported more than 70 years ago, the diagnosis is rarely considered when a patient presents with syncope and hypoglycemia. This article reports a patient who presented with a large pleural mass and a hypoglycemic syndrome. (The disease was surgically cured.) The probable mechanism of hypoglycemia is discussed.
authors.affiliation: Department of Intensive Care Unit, King Fahad National Guard Hospital Riyadh, Kingdom of Saudi Arabia.
authors.forename: Naeem
authors.initials: N
authors.lastname: Adhami
authors.forename: Raees
authors.initials: R
authors.lastname: Ahmed
authors.forename: Patrick A
authors.initials: PA
authors.lastname: Lento
authors.forename: Mona
authors.initials: M
authors.lastname: Shimshi
authors.forename: Steven D
authors.initials: SD
authors.lastname: Herman
authors.forename: Alvin S
authors.initials: AS
authors.lastname: Teirstein
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D007003:Hypoglycemia / Q000175:diagnosis* / Q000209:etiology; D008875:Middle Aged; D018218:Neoplasms, Fibrous Tissue / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D010997:Pleural Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D017526:Receptor, IGF Type 1; D017527:Receptor, IGF Type 2; D013908:Thoracotomy
chemical_list: D017527:Receptor, IGF Type 2; D017526:Receptor, IGF Type 1