The lack of evidence for ELF magnetic-field effects on bilayer membranes and reconstituted membrane channels.
The effects of low-frequency (10-500 Hz) magnetic fields on the electrical properties of channel-free bilayer membranes, and on the single-channel conductance and macroscopic gating characteristics of porin channels incorporated into membranes, have been studied for field strengths in the range 10-100 microT. The field conditions that could in theory give rise to 'cyclotron resonance' effects were also studied. No evidence has been found to support the concept that cyclotron resonance and membrane ion channel effects are involved in the reported biological effects of ELF magnetic fields.
Burt
J P
JP
Institute of Molecular and Biomolecular Electronics, University of Wales, Dean Street, Bangor, Gwynedd LL57 1UT, UK.
Morgan
H
H
Pethig
R
R
D004307:Dose-Response Relationship, Radiation; D004553:Electric Conductivity; D004574:Electromagnetic Fields; D015640:Ion Channel Gating / Q000528:radiation effects*; D008051:Lipid Bilayers / Q000737:chemistry* / Q000528:radiation effects*; D008560:Membrane Fluidity / Q000528:radiation effects*; D008564:Membrane Potentials / Q000528:radiation effects; D008567:Membranes, Artificial; D018272:Porins / Q000737:chemistry* / Q000528:radiation effects*; D011829:Radiation Dosage
D008051:Lipid Bilayers; D008567:Membranes, Artificial; D018272:Porins