Deep brain stimulation of the subthalamic nucleus reduces antiparkinsonian medication costs.
This study reports a retrospective analysis of 16 patients to determine changes in medication costs associated with deep brain stimulation of the bilateral subthalamic nucleus (DBS B-STN). Antiparkinsonian medication (APMED) costs were evaluated pre- and post-operatively at 1 and 2 years, based on prescribed dosages. After treatment with DBS, patients experienced a 32% reduction in APMED costs after 1 year and a 39% reduction after 2 years. Hypothetical projections of total potential savings are presented, accounting for increasingly complex medication regimens and medication cost inflation. DBS patients may experience a significant long-term reduction in the cost of their pharmacologic treatment.
Charles
P David
PD
The Movement Disorders Clinic, Department of Neurology, Vanderbilt University Medical Center, 2100 Pierce Avenue, Suite 352 MCS, Vanderbilt University, Nashville, TN 37212-3375, USA. p.david.charles@vanderbilt.edu
Padaliya
Bimal B
BB
Newman
William J
WJ
Gill
Chandler E
CE
Covington
Cassondra D
CD
Fang
John Y
JY
So
Stephanie A
SA
Tramontana
Michael G
MG
Konrad
Peter E
PE
Davis
Thomas L
TL
D000547:Amantadine / Q000191:economics / Q000627:therapeutic use; D000978:Antiparkinson Agents / Q000008:administration & dosage / Q000191:economics* / Q000627:therapeutic use*; D065098:Catechol O-Methyltransferase Inhibitors; D003131:Combined Modality Therapy; D046690:Deep Brain Stimulation / Q000191:economics; D016527:Drug Costs; D004567:Electrodes, Implanted; D004791:Enzyme Inhibitors / Q000191:economics / Q000627:therapeutic use; D006801:Humans; D007980:Levodopa / Q000191:economics / Q000627:therapeutic use; D018803:Models, Economic; D019635:Neurosurgical Procedures; D010300:Parkinson Disease / Q000188:drug therapy / Q000191:economics* / Q000628:therapy*; D012189:Retrospective Studies; D020531:Subthalamic Nucleus / Q000502:physiology*
D000978:Antiparkinson Agents; D065098:Catechol O-Methyltransferase Inhibitors; D004791:Enzyme Inhibitors; D007980:Levodopa; D000547:Amantadine