title: Neurosarcoidosis--review of imaging findings.
abstract: Five to 25% of patients with systemic sarcoidosis also have CNS involvement. Patients with systemic disease may initially present with neurologic symptoms, and rarely, the sarcoidosis may be isolated to the CNS. A typical imaging feature is thickening and enhancement of the basilar leptomeninges of the brain. Other imaging findings, such as enhancing or nonenhancing parenchymal lesions, dural, and bone lesions may occur in the head and spine. Because there is a high rate of progression and recurrence following treatment, imaging follow-up is recommended in all patients.
authors.affiliation: Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7510, USA. klury@med.unc.edu
authors.forename: Kenneth M
authors.initials: KM
authors.lastname: Lury
authors.forename: J Keith
authors.initials: JK
authors.lastname: Smith
authors.forename: Maria Gisele
authors.initials: MG
authors.lastname: Matheus
authors.forename: Mauricio
authors.initials: M
authors.lastname: Castillo
mesh_terms: D002493:Central Nervous System Diseases / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D012507:Sarcoidosis / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed