Efficient synthesis of 1-adamantanecarboxaldehyde by the GaCl3-mediated carbonylation of adamantane under mild reaction conditions.
The reaction of adamantane (1) with CO (1 atm) in 1,2-dichloroethane at room temperature in the presence of GaCl(3) results in formylation to give 1-adamantanecarboxaldehyde (2) in up to 84% yield.
Oshita
Masayuki
M
Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Chatani
Naoto
N