title: Palladium-catalyzed borylation of phenyl bromides and application in one-pot Suzuki-Miyaura biphenyl synthesis.
abstract: The coupling reaction of pinacolborane with various aryl bromides in the presence of a catalytic amount of Pd(OAc)(2) together with DPEphos as ligand and Et(3)N as base provided arylboronates. High yields were obtained in the case of electron-donor substituted aryl bromides. The direct preparation of arylboronates allowed the one-pot, two-step synthesis of unsymmetrical biaryls in high yields. [reaction: see text]
authors.affiliation: Laboratoire de Stéréochimie associé au CNRS (UMR 7008), Université Louis Pasteur (ECPM), 25 rue Becquerel, F-67087 Strasbourg Cedex 2, France.
authors.forename: Pierre-Emmanuel
authors.initials: PE
authors.lastname: Broutin
authors.forename: Igor
authors.initials: I
authors.lastname: Cerna
authors.forename: Maria
authors.initials: M
authors.lastname: Campaniello
authors.forename: Frédéric
authors.initials: F
authors.lastname: Leroux
authors.forename: Françoise
authors.initials: F
authors.lastname: Colobert