[Protective effect of ganfukang capsule on hepatocytes in rats with experimental hepatic fibrosis].
OBJECTIVE
To observe the protective effect of ganfukang capsule on hepatocytes of rats with experimental hepatic fibrosis rat.


METHODS
SD rat model of liver fibrosis was induced by CCl4. The effect of ganfukang capsule on liver function, histological change and ultrastructural were examined.


RESULTS
Liver function, histological change and ultrastructural were significantly improved. The degree of steatosis was significantly decreased.


CONCLUSIONS
Ganfukang capsule might protect hepatocytes, mitochondria from the injury induced by CCl4 and improve liver function.
Che
Ying
Y
The First Affiliated Hospital of Dalian Medical University.
Xu
Tingting
T
Jiang
Miaona
M
Jia
Yujie
Y
D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D002214:Capsules; D002252:Carbon Tetrachloride Poisoning; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D022781:Hepatocytes / Q000187:drug effects* / Q000473:pathology; D008106:Liver Cirrhosis, Experimental / Q000139:chemically induced / Q000378:metabolism / Q000473:pathology*; D008111:Liver Function Tests; D020011:Protective Agents / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley
D002214:Capsules; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D020011:Protective Agents; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase