title: [Cranial hyperostosis as a metastasic adenocarcinoma presentation form].
abstract: Hyperostosis is a volume-unit osseous increase of very diverse etiology. We present the case of a 68-year woman with a cranial hyperostosis debuting with frontal protrusion, headache and neurologic symptoms. Image proves demonstrated a hyperostosis in the calotte and meningeal enhancement, without intracerebral lesions nor malignant cells in the cerebrospinal fluid. Analytic data were unspecific. Cranial biopsy showed huge neoplastic infiltration in bone and meninges. Primary site remained unknown after a CAT and a mammography.
authors.affiliation: Servicio de Medicina Interna, Hospital Universitario La Fe, Valencia, Spain. Lu_sua@hotmail.com
authors.forename: L
authors.initials: L
authors.lastname: Suárez Alvarez
authors.forename: N
authors.initials: N
authors.lastname: Muelas Gómez
authors.forename: J A
authors.initials: JA
authors.lastname: Todolí Parra
authors.forename: T
authors.initials: T
authors.lastname: Sevilla Mantecón
authors.forename: J R
authors.initials: JR
authors.lastname: Calabuig Alborch
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000556:secondary*; D000368:Aged; D005260:Female; D006801:Humans; D006957:Hyperostosis Frontalis Interna / Q000175:diagnosis* / Q000209:etiology; D008577:Meningeal Neoplasms / Q000150:complications / Q000556:secondary*; D009382:Neoplasms, Unknown Primary; D012888:Skull Neoplasms / Q000150:complications / Q000556:secondary*