title: In vivo and in vitro activities of the seed extract of Piper guineense Schum. and Thonn. against skin and gill monogenean parasites of gold fish (Carassius auratus auratus).
abstract: Methanol extracts of the seeds of Piper guineense (Piperaceae) were active against gold fish (Carassius auratus auratus L. Pisces Cyprinidae) monogenean parasites. The seed extract of P. guineense was administered at different concentrations (0.5-2.0 mg/L) under in vivo and in vitro conditions. There was a higher efficacy of the effects of the extracts against fish parasites under in vitro situations than under in vivo. Three major compounds (piperanine, N-isobutyl (E,E)-2,4 decadienamide and Deltaalpha,beta-dihydrowasanine) were identified from the seed extract of Piper guineense by LC-MS analysis.
authors.affiliation: Institute of Oceanography, University of Calabar, P.M.B. 1115, Calabar, Nigeria. albertekanem@yahoo.com
authors.forename: A P
authors.initials: AP
authors.lastname: Ekanem
authors.forename: M
authors.initials: M
authors.lastname: Wang
authors.forename: J E
authors.initials: JE
authors.lastname: Simon
authors.forename: A I
authors.initials: AI
authors.lastname: Obiekezie
authors.forename: F
authors.initials: F
authors.lastname: Morah
mesh_terms: D000818:Animals; D005393:Fish Diseases / Q000188:drug therapy / Q000469:parasitology; D005880:Gills / Q000469:parasitology; D006054:Goldfish / Q000469:parasitology*; D006374:Helminthiasis, Animal / Q000188:drug therapy / Q000469:parasitology; D021261:Parasitic Sensitivity Tests; D008517:Phytotherapy; D031701:Piper; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D010986:Platyhelminths / Q000187:drug effects*; D012639:Seeds; D012867:Skin / Q000469:parasitology
chemical_list: D010936:Plant Extracts