title: Impact of radical hysterectomy for cervical cancer on urodynamic findings.
abstract: To elucidate the impact of radical hysterectomy upon the urodynamic findings of patients with cervical cancer, 20 patients with cervical cancer at stage IB to IIA who underwent radical hysterectomy were recruited. Each patient underwent a 20-min pad test and urodynamic study prior to and 3 months after radical hysterectomy. ANOVA, Bonferroni test and paired t -test were utilized for analysis. The mean age of the 20 patients was 50.2+/-8.7 years with a mean parity of 3.5+/-1.5. Four (20%) of the 20 cases revealed normal urodynamic findings preoperatively, and the urodynamic findings became abnormal after surgery. Comparing the urodynamic parameters of both bladder voiding and storage functions pre- and post-surgery, we found significant impairments postoperatively in all 20 cases. Our data demonstrate that abnormal urodynamic findings may pre-exist for some patients with cervical cancer prior to surgical treatment. These findings may worsen, and/or additional abnormal states may arise subsequent to radical hysterectomy.
authors.affiliation: Department of Obstetrics and Gynecology, Chung-Shan Medical University, Taichung, Taiwan.
authors.forename: Long-Yau
authors.initials: LY
authors.lastname: Lin
authors.forename: Jian-Hong
authors.initials: JH
authors.lastname: Wu
authors.forename: Chiong-Wu
authors.initials: CW
authors.lastname: Yang
authors.forename: Bor-Ching
authors.initials: BC
authors.lastname: Sheu
authors.forename: Ho-Hsiung
authors.initials: HH
authors.lastname: Lin
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D008875:Middle Aged; D011182:Postoperative Care; D011300:Preoperative Care; D012189:Retrospective Studies; D012212:Rheology; D014521:Urethra / Q000503:physiopathology; D001743:Urinary Bladder / Q000503:physiopathology; D014563:Urodynamics / Q000502:physiology*; D002583:Uterine Cervical Neoplasms / Q000503:physiopathology* / Q000601:surgery*