[A case of allergic fungal sinusitis caused by Bipolaris spicifera].
We describe a case of allergic fungal sinusitis (AFS) caused by Bipolaris spicifera, the first case reported in Japan. A 70-year-old man was admitted to our hospital because of diplopia following bilateral nasal obstruction and discharge. Radiological studies using computed tomographic scan showed a large soft tissue mass occupying the right frontal, bilateral ethmoid and sphenoid sinuses. He underwent drainage surgery and histopathological examination of the contents of the paranasal sinuses revealed scattered fungal hyphae within "allergic mucin". By cytological examination, these hyphae showed septation at irregular intervals, and were swollen to various sizes. Microbiological studies identified the fungus as Bipolaris spicifera. The presence of allergic mucin and scattered fungal hyphae were very important findings in making a diagnosis of AFS histopathologically, so squash cytology of the contents of the paranasal sinuses was quite useful to observe fungal elements and identify the strain in this case.
Taguchi
Katsuji
K
Department of Pathology, Ohashi Hospital, Toho University School of Medicine, 2-17-6 Ohashi, Meguro-ku, Tokyo 153-8515, Japan.
Kawabata
Tomoko
T
Wakayama
Megumi
M
Oharaseki
Toshiaki
T
Yokouchi
Yuki
Y
Takahashi
Kei
K
Naoe
Shiro
S
Ogoshi
Toshio
T
Iwabuchi
Satoshi
S
Shibuya
Kazutoshi
K
Nishimura
Kazuko
K
D000368:Aged; D001203:Ascomycota / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D008297:Male; D012130:Respiratory Hypersensitivity / Q000150:complications*; D012852:Sinusitis / Q000209:etiology*