Inhalation of nitric oxide in the treatment of severe acute respiratory syndrome: a rescue trial in Beijing.
Inhalation of nitric oxide (NO) improved arterial oxygenation and enabled the reduction of inspired oxygen therapy and airway pressure support in patients with severe acute respiratory syndrome (SARS). In addition, chest radiography showed decreased spread or density of lung infiltrates, and the physiological effects remained after termination of inhaled NO therapy. These findings suggest not only a pulmonary vasodilator effect of inhaled NO, but also an effect on SARS.
Chen
Luni
L
Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.
Liu
Peng
P
Gao
He
H
Sun
Bing
B
Chao
Desheng
D
Wang
Fei
F
Zhu
Yuanjue
Y
Hedenstierna
Göran
G
Wang
Chen G
CG
D000280:Administration, Inhalation; D000328:Adult; D002681:China; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009569:Nitric Oxide / Q000008:administration & dosage*; D045169:Severe Acute Respiratory Syndrome / Q000188:drug therapy*
D009569:Nitric Oxide