[Damage to erythrocyte membranes induced by high-intensity ultrasound].
The effect of high-intensity ultrasound (11.2-54.2 W/cm2, frequency 36 kHz) on the structural and functional state of erythrocytes was investigated. It was shown that, at short-term action of the ultrasound (up to 1 min), the dose-dependent hemolysis of erythrocytes occurs. It was found that the exposure to ultrasound of high intensity (54.2 W/cm2) leads to the disruption of the structural state of erythrocyte membranes, which manifests itself in a change of microviscosity of the lipid bilayer of membranes and inhibition of the activity of the lipid-dependent membrane-bound enzyme acetylcholinesterase.
Adzerikho
I E
IE
Kozlova
N M
NM
Antonovich
A N
AN
Zubritskaia
G P
GP
Slobozhanina
E I
EI
D000110:Acetylcholinesterase / Q000378:metabolism; D004910:Erythrocyte Membrane / Q000737:chemistry* / Q000201:enzymology*; D006461:Hemolysis; D006801:Humans; D008051:Lipid Bilayers / Q000378:metabolism; D014465:Ultrasonics
D008051:Lipid Bilayers; D000110:Acetylcholinesterase