title: Intracranial metastatic esthesioneuroblastoma responsive to temozolomide.
abstract: Successful management of a heavily pretreated 58-year-old woman with metastatic esthesioneuoblastoma using temozolomide is reported. There is no standard treatment of this tumors with extra- and intracranial manifestations. The response, long term stability and high quality of life using temozolomide for this tumor entity should be recognized.
authors.affiliation: Department of Neurology, University of Tübingen Medical School, Tübingen, Germany. wolfgang.wick@uni-tuebingen.de
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Wick
authors.forename: Antje
authors.initials: A
authors.lastname: Wick
authors.forename: Wilhelm
authors.initials: W
authors.lastname: Küker
authors.forename: Johannes
authors.initials: J
authors.lastname: Dichgans
authors.forename: Michael
authors.initials: M
authors.lastname: Weller
mesh_terms: D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000556:secondary; D003606:Dacarbazine / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D018304:Esthesioneuroblastoma, Olfactory / Q000188:drug therapy* / Q000556:secondary; D005260:Female; D006801:Humans; D008875:Middle Aged; D009296:Nasal Cavity / Q000473:pathology*; D009669:Nose Neoplasms / Q000188:drug therapy* / Q000473:pathology; D011788:Quality of Life; D000077204:Temozolomide
chemical_list: D018906:Antineoplastic Agents, Alkylating; D003606:Dacarbazine; D000077204:Temozolomide