Testicular seminoma 16 years after treatment for CNS germinoma.
Most patients with intracranial germinomas will be cured and become long-term survivors. Physicians caring for these patients should recognize that these patients may be at risk for disease-related and/or treatment-related late sequelae. We report the case of a 27-year-old man who developed testicular seminoma 16 years after treatment for intracranial germinoma. Like their testicular cancer counterparts, long-term survivors of intracranial germinomas may have a susceptibility to develop a subsequent germ cell tumor. These patients require lifelong medical follow-up and should be encouraged to perform testicular self-examination at the appropriate age.
Maity
Amit
A
Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia 19104, USA. maity@xrt.upenn.edu
Shu
Hui-Kuo G
HK
Judkins
Alexander R
AR
Fisher
Michael J
MJ
Dwyer-Joyce
Lisa E A
LE
Vaughn
David J
DJ
D000328:Adult; D000359:Aftercare; D001932:Brain Neoplasms / Q000473:pathology* / Q000628:therapy; D016371:Cranial Irradiation; D003399:Craniotomy; D018237:Germinoma / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary; D018239:Seminoma / Q000473:pathology* / Q000601:surgery; D013736:Testicular Neoplasms / Q000473:pathology* / Q000628:therapy