Acneiform eruption induced by Iressa (gefitinib) tablets used to treat non-small cell lung cancer.
Many medications have been reported to induce acneiform eruptions. A relatively new chemotherapy drug, gefitinib (Iressa), approved by the Food and Drug Administration in 2003 for the treatment of advanced-stage non-small cell lung cancer (NSCLC), has been reported to cause acne or an acne-like eruption. We report an Asian female who presented with hundreds of erythematous papules and pustules on her face, chest, and back, all of which appeared after starting gefitinib to treat non-small cell lung cancer.
Warthan
Molly M
MM
Texas Tech University Health Sciences Center Lubbock, Texas 79424, USA.
Jumper
Cynthia A
CA
Smith
Jennifer L
JL
D017486:Acneiform Eruptions / Q000139:chemically induced*; D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy; D005260:Female; D000077156:Gefitinib; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy; D011799:Quinazolines / Q000009:adverse effects*; D013607:Tablets
D000970:Antineoplastic Agents; D011799:Quinazolines; D013607:Tablets; D000077156:Gefitinib