title: [A case of allergic fungal sinusitis caused by Bipolaris spicifera].
abstract: We describe a case of allergic fungal sinusitis (AFS) caused by Bipolaris spicifera, the first case reported in Japan. A 70-year-old man was admitted to our hospital because of diplopia following bilateral nasal obstruction and discharge. Radiological studies using computed tomographic scan showed a large soft tissue mass occupying the right frontal, bilateral ethmoid and sphenoid sinuses. He underwent drainage surgery and histopathological examination of the contents of the paranasal sinuses revealed scattered fungal hyphae within "allergic mucin". By cytological examination, these hyphae showed septation at irregular intervals, and were swollen to various sizes. Microbiological studies identified the fungus as Bipolaris spicifera. The presence of allergic mucin and scattered fungal hyphae were very important findings in making a diagnosis of AFS histopathologically, so squash cytology of the contents of the paranasal sinuses was quite useful to observe fungal elements and identify the strain in this case.
authors.affiliation: Department of Pathology, Ohashi Hospital, Toho University School of Medicine, 2-17-6 Ohashi, Meguro-ku, Tokyo 153-8515, Japan.
authors.forename: Katsuji
authors.initials: K
authors.lastname: Taguchi
authors.forename: Tomoko
authors.initials: T
authors.lastname: Kawabata
authors.forename: Megumi
authors.initials: M
authors.lastname: Wakayama
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Oharaseki
authors.forename: Yuki
authors.initials: Y
authors.lastname: Yokouchi
authors.forename: Kei
authors.initials: K
authors.lastname: Takahashi
authors.forename: Shiro
authors.initials: S
authors.lastname: Naoe
authors.forename: Toshio
authors.initials: T
authors.lastname: Ogoshi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Iwabuchi
authors.forename: Kazutoshi
authors.initials: K
authors.lastname: Shibuya
authors.forename: Kazuko
authors.initials: K
authors.lastname: Nishimura
mesh_terms: D000368:Aged; D001203:Ascomycota / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D008297:Male; D012130:Respiratory Hypersensitivity / Q000150:complications*; D012852:Sinusitis / Q000209:etiology*