title: [Usefulness of F-18-fluorodeoxyglucose positron emission tomography for evaluating the efficacy of transient hepatic arterial chemoembolization for liver metastases of rectal cancer--a case report].
abstract: It is pointed out that there can be a discrepancy between the effect diagnosed by radiographic imaging and that by histological examination, when we treat patients with liver metastases of colorectal cancer by a transient hepatic arterial chemoembolization. We report a case of liver metastases of rectal cancer in which F-18-fluorodeoxyglucose positron emission tomography (FDG-PET) was useful for evaluating the therapeutic efficacy for transient hepatic arterial chemoembolization. A 58-year-old man with synchronous liver metastases (H2) of rectal cancer underwent a low anterior resection, a partial hepatectomy, cholecystectomy, and ligation of the gastroduodenal artery. After these operations, the patient received 6 hepatic arterial injections with degradable starch microspheres (300-600 mg), adriamycin (30 mg), and mitomycin C (10 mg) for the remaining metastatic lesion (S7). Although abdominal CT scan revealed a partial response, FDG-PET did not show any abnormal deposits. Hepatic posterior segmentectomy was performed 7 months after the first operation. Histological examination did not show any viable tumor cells in the resected specimen.
authors.affiliation: Dept. of Surgery, Saitama Medical Center, Saitama Medical School.
authors.forename: Masaru
authors.initials: M
authors.lastname: Yokoyama
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Ishida
authors.forename: Ikuya
authors.initials: I
authors.lastname: Takeuchi
authors.forename: Norimichi
authors.initials: N
authors.lastname: Okada
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nakada
authors.forename: Tomonori
authors.initials: T
authors.lastname: Ohsawa
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Ozawa
authors.forename: Takanobu
authors.initials: T
authors.lastname: Hoshino
authors.forename: Daijyo
authors.initials: D
authors.lastname: Hashimoto
mesh_terms: D016461:Chemoembolization, Therapeutic; D002763:Cholecystectomy; D004317:Doxorubicin / Q000008:administration & dosage; D019788:Fluorodeoxyglucose F18; D006498:Hepatectomy; D006499:Hepatic Artery; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy*; D008297:Male; D008863:Microspheres; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D049268:Positron-Emission Tomography; D012004:Rectal Neoplasms / Q000473:pathology*; D013213:Starch / Q000008:administration & dosage
chemical_list: D019788:Fluorodeoxyglucose F18; D016685:Mitomycin; D004317:Doxorubicin; D013213:Starch