Management of traumatic brain injury: some current evidence and applications.
Traumatic brain injury remains a worldwide problem. Newer modalities in the management of such injuries include both drugs and therapeutic strategies. Continuing research in animal models has provided a better understanding of the pathophysiological processes that follow head injury, and this in turn has enabled workers to work on improved treatment targets. Although there are exciting and novel approaches emerging, there is no substitute for meticulous initial resuscitation. Additionally, some of the more well known management options are now better understood. These concepts are discussed in the article.
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Walton Centre for Neurology and Neurosurgery and University Hospital Aintree, Longmoor Lane, Liverpool L9 7AL, UK. arpan1@yahoo.com
D015502:Absorptiometry, Photon; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001463:Barbiturates / Q000627:therapeutic use; D001930:Brain Injuries / Q000209:etiology / Q000628:therapy*; D002986:Clinical Trials as Topic; D004234:Diuretics, Osmotic / Q000627:therapeutic use; D013759:Dronabinol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D006874:Hydrostatic Pressure; D007035:Hypothermia / Q000628:therapy; D008353:Mannitol / Q000627:therapeutic use; D019148:Neuromuscular Blockade; D018696:Neuroprotective Agents / Q000627:therapeutic use; D009997:Osmotic Pressure; D012965:Sodium Chloride / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D001463:Barbiturates; D004234:Diuretics, Osmotic; D018696:Neuroprotective Agents; D008353:Mannitol; D012965:Sodium Chloride; D013759:Dronabinol; C062018:HU 211