Generalized Langevin equation with fractional Gaussian noise: subdiffusion within a single protein molecule.
By introducing fractional Gaussian noise into the generalized Langevin equation, the subdiffusion of a particle can be described as a stationary Gaussian process with analytical tractability. This model is capable of explaining the equilibrium fluctuation of the distance between an electron transfer donor and acceptor pair within a protein that spans a broad range of time scales, and is in excellent agreement with a single-molecule experiment.
Kou
S C
SC
Department of Statistics and Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Xie
X Sunney
XS
D038181:FMN Reductase / Q000737:chemistry* / Q000378:metabolism; D005182:Flavin-Adenine Dinucleotide / Q000737:chemistry / Q000378:metabolism; D005453:Fluorescence; D008956:Models, Chemical; D008958:Models, Molecular; D011487:Protein Conformation; D014443:Tyrosine / Q000737:chemistry / Q000378:metabolism
D005182:Flavin-Adenine Dinucleotide; D014443:Tyrosine; D038181:FMN Reductase