Multiple cutaneous reticulohistiocytomas in a patient with rheumatoid arthritis.
A 64-year-old woman with a long-standing peripheral symmetric polyarthritis with positive rheumatoid serology was evaluated for multiple asymptotic papulonodules of fingers, mentum, lower lip, ears, and eyelids. Histopathologic examination showed a dermal infiltrate composed of histiocytes, multinucleate giant cells with ground-glass cytoplasm, and lymphocytes, suggestive of reticulohistiocytoma. The possibilities of multicentric reticulohistiocytosis with positive rheumatoid serology or coexistence of multiple cutaneous reticulohistiocytomas and rheumatoid arthritis are discussed.
Vieira
Ricardo
R
Department of Dermatology, University Hospital, Coimbra, Portugal. ricardojvieira@aeiou.pt
Cordeiro
Margarida Robalo
MR
Mariano
Angelina
A
Reis
Jose Pedro
JP
Tellechea
Oscar
O
Figueiredo
Americo
A
D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000473:pathology*; D005260:Female; D015616:Histiocytosis, Non-Langerhans-Cell / Q000150:complications* / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D012871:Skin Diseases / Q000150:complications* / Q000473:pathology*