The unknown nuclear protein that decreases HNF3 activity ensures species specificity of action of hepatocarcinogenic amino azo dyes.
Kropachev
K Yu
KY
Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, pr Akademika Lavrent'eva 10, Novosibirsk, 630090 Russia.
Pakharukova
M Yu
MY
Bryzgalov
L O
LO
Kaledin
V I
VI
Kobzev
V F
VF
Merkulova
T I
TI
D000818:Animals; D004396:Coloring Agents / Q000494:pharmacology*; D004268:DNA-Binding Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism*; D004052:Diethylnitrosamine / Q000494:pharmacology; D015536:Down-Regulation; D051541:Hepatocyte Nuclear Factor 3-alpha; D008099:Liver / Q000187:drug effects*; D008297:Male; D008749:Methyldimethylaminoazobenzene / Q000494:pharmacology*; D051379:Mice; D009687:Nuclear Proteins / Q000032:analysis / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000502:physiology*; D051381:Rats; D013045:Species Specificity; D014157:Transcription Factors / Q000037:antagonists & inhibitors / Q000378:metabolism*; D009762:o-Aminoazotoluene / Q000494:pharmacology*
D004396:Coloring Agents; D004268:DNA-Binding Proteins; C496500:Foxa1 protein, mouse; C496501:Foxa1 protein, rat; D051541:Hepatocyte Nuclear Factor 3-alpha; D009687:Nuclear Proteins; D014157:Transcription Factors; D004052:Diethylnitrosamine; D008749:Methyldimethylaminoazobenzene; D009762:o-Aminoazotoluene