title: Thromboembolic events and haematological diseases: a case of stroke as clinical onset of a paroxysmal nocturnal haemoglobinuria.
abstract: Some haematological diseases are associated to an increased risk of thromboembolic events. We report a case of paroxysmal nocturnal haemoglobinuria (PNH) in which a cerebrovascular event represented the first clinical manifestation of disease. PNH is associated to thromboembolic events, generally of venous districts often involving unusual locations such as mesenteric vessels, sagittal veins, inferior vena cava and renal veins.To our knowledge arterial thrombotic episodes are rare and the involvement of arterial cerebral vessels is exceptional. Then, our case points out the importance of investigating about haematological disorders in all patients presenting with a stroke, in which the common predisposing conditions are excluded.
authors.affiliation: Internal Medicine of Second University of Naples, Naples, Italy. calimero.pocali@libero.it.
authors.forename: Gianluca
authors.initials: G
authors.lastname: Granata
authors.forename: Tiziana
authors.initials: T
authors.lastname: Izzo
authors.forename: Pierpaolo
authors.initials: P
authors.lastname: Di Micco
authors.forename: Barbara
authors.initials: B
authors.lastname: Bonamassa
authors.forename: Giampiero
authors.initials: G
authors.lastname: Castaldo
authors.forename: Vito Giuseppe
authors.initials: VG
authors.lastname: Viggiano
authors.forename: Ugo
authors.initials: U
authors.lastname: Picillo
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Castaldo
authors.forename: Alferio
authors.initials: A
authors.lastname: Niglio