title: [Ethmoid adenocarcinoma: trans-facial approach for anterior skull base resection. a series of 80 cases].
abstract: OBJECTIVE
  To present results of a retrospective analysis of eighty cases of ethmoid adenocarcinoma. Carcinologic and surgical results of anterior skull base resection via the transfacial approach are presented.
  
  
  METHODS
  Tumors were classified as 5% T1, 23% T2, 31% T3, 21% T4a and 20% T4b. Thirty-four patients were treated via a paralateronasal approach without skull base resection. Anterior skull bas resections were performed via the transfacial approach for 26 patients and by combined neurosurgical approach for 21.
  
  
  RESULTS
  Mean follow-up was 4.8 years. Survival rate was 63.4% at 5 years and 57.9% at 8 years. Forty-two patients were alive and disease-free at last follow-up. Three patients were alive with recurrence. The rate of local recurrence was 38.8%. Complications occurred in 20% of the patients who had a transfacial approach. Complications appeared to be less frequent than with the combined approach.
  
  
  CONCLUSIONS
  Prognosis is related to local control and could be improved by using skull base resection more systematically. In our experience this can be managed by a transfacial approach with similar carcinological results and less complications than the combined approach.
authors.affiliation: Service d'ORL et chirurgie cervico-faciale, Hotel-Dieu, place A. Ricordeau, 44093 Nantes Cedex 1, France. fjegoux@free.fr
authors.forename: Fr
authors.initials: F
authors.lastname: Jegoux
authors.forename: Ch
authors.initials: Ch
authors.lastname: Ferron
authors.forename: O
authors.initials: O
authors.lastname: Malard
authors.forename: G
authors.initials: G
authors.lastname: Cariou
authors.forename: A
authors.initials: A
authors.lastname: Faure
authors.forename: C
authors.initials: C
authors.lastname: Beauvillain De Montreuil
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005004:Ethmoid Bone / Q000473:pathology* / Q000601:surgery*; D005145:Face; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods*; D010255:Paranasal Sinus Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D019291:Skull Base / Q000601:surgery*; D015996:Survival Rate