title: Prospective psychosocial monitoring of living kidney donors using the Short Form-36 health survey: results at 12 months.
abstract: BACKGROUND
  Lack of prospective psychosocial outcome studies on living kidney donors impedes identification of risk factors for poor outcome.
  
  
  METHODS
  Psychiatric assessment of living kidney donors was performed preoperatively and at 4 and 12 months postoperatively using a semistructured interview, the Short Form (SF)-36 Health Survey, and Patient Health Questionnaire psychiatric assessment. A total of 48 of 51 consecutive donors (94%) over a 5-year period were available for follow-up and completed all assessments.
  
  
  RESULTS
  At preoperative assessment, only 1 of the 48 donors (2%) had a Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition Axis I psychiatric disorder, but 15 (31%) developed a disorder during the 12 months, a 29% incidence. Disorders were depressive (12%), anxiety (6%), and adjustment (13%). Seven donors (15%) demonstrated a disorder at 12 months (depressive 10%, anxiety 2%, adjustment 2%). There was a corresponding decline in psychosocial function as measured by the SF-36 Mental Component Summary score; it decreased at both 4 and 12 months (P<0.01, P<0.05); for 19% of donors, this was a larger decrease than would be expected for the cohort (>2 standard error of measurement units). Scores for SF-36 scales of General Health and Vitality decreased significantly (P<0.05), as did those of Bodily Pain, indicating greater impairment from pain. Psychiatric disorder at 12 months was associated with donor psychosocial function (Mental Component Summary) and psychiatric disorder at 4 months (P<0.01), physical function (SF-36 Physical Component Summary score) at 4 and 12 months (P<0.01), and recipient psychiatric disorder at 12 months (P<0.05).
  
  
  CONCLUSIONS
  Donors should be alerted to possible psychosocial impairment, assessed for risk factors, and monitored for at least 12 months. Treatment should be available.
authors.affiliation: Consultation-Liaison Psychiatry Service and Monash University Department of Psychological Medicine, Monash Medical Centre, Southern Health, Clayton VIC 3168, Australia. graeme.smith@med.monash.edu.au
authors.forename: Graeme C
authors.initials: GC
authors.lastname: Smith
authors.forename: Thomas
authors.initials: T
authors.lastname: Trauer
authors.forename: Peter G
authors.initials: PG
authors.lastname: Kerr
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Chadban
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D000368:Aged; D001007:Anxiety / Q000453:epidemiology; D003863:Depression / Q000453:epidemiology; D005260:Female; D006306:Health Surveys; D006801:Humans; D016030:Kidney Transplantation; D019520:Living Donors / Q000523:psychology*; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology*; D008875:Middle Aged; D011446:Prospective Studies