Tyr204Phe and Val34Leu polymorphisms in two Brazilian ethnic groups and in patients with recurrent miscarriages.
This study investigated the prevalence of Tyr204Phe and Val34Leu polymorphisms in two Brazilian ethnic groups (171 Caucasians and 27 Blacks, and 117 men and 81 women) and in patients with recurrent miscarriages (RM) (86 women: 53 Caucasians and 33 Blacks). Study groups were matched to control groups by race and age. The prevalence of these polymorphisms did not differ between patients with RM and controls or between Caucasian and blacks, suggesting that these polymorphisms cannot be considered a risk factor for RM.
Barbosa
Helena C L
HC
Hematology and Hemotherapy Center, State University of Campinas, Campinas, São Paulo, Brazil.
Carvalho
Egle C C
EC
Barini
Ricardo
R
Siqueira
Lucia Helena
LH
Costa
Devanira S P
DS
Annichino-Bizzacchi
Joyce M
JM
D000026:Abortion, Habitual / Q000235:genetics*; D044383:Black People / Q000235:genetics*; D001938:Brazil / Q000208:ethnology; D005176:Factor XIII / Q000235:genetics*; D005260:Female; D006801:Humans; D007930:Leucine; D008297:Male; D010649:Phenylalanine; D011110:Polymorphism, Genetic; D011247:Pregnancy; D014443:Tyrosine; D014633:Valine; D044465:White People / Q000235:genetics*
D014443:Tyrosine; D010649:Phenylalanine; D005176:Factor XIII; D007930:Leucine; D014633:Valine