title: Enantioselective synthesis of 2- and 3-substituted 2,3-dihydro[1,4]dioxino[2,3-b]pyridine derivatives and enantiomeric purity control by capillary electrophoresis.
abstract: A rapid and simple procedure for enantioselective preparation of 2- and 3-substituted 2,3-dihydro[1,4]dioxino[2,3-b]pyridine derivatives (A and B, respectively) is described. The enantiomeric purity of each isomer was determined by capillary electrophoresis using a dual-cyclodextrin system (S-beta-CD/beta-CD) dissolved in formic acid-ammonia buffer (pH 4, ionic strength 50 mM).
authors.affiliation: Laboratoire de Chimie Bioorganique et Analytique, Université Hassan II--Mohammédia, Morocco.
authors.forename: S
authors.initials: S
authors.lastname: Lazar
authors.forename: M
authors.initials: M
authors.lastname: Soukri
authors.forename: M
authors.initials: M
authors.lastname: El Haddad
authors.forename: M
authors.initials: M
authors.lastname: Akssira
authors.forename: J M
authors.initials: JM
authors.lastname: Leger
authors.forename: C
authors.initials: C
authors.lastname: Jarry
authors.forename: Ph
authors.initials: P
authors.lastname: Morin
authors.forename: G
authors.initials: G
authors.lastname: Guillaumet
mesh_terms: D019075:Electrophoresis, Capillary / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism; D014961:X-Ray Diffraction
chemical_list: D011725:Pyridines