title: Bollgard II cotton: compositional analysis and feeding studies of cottonseed from insect-protected cotton (Gossypium hirsutum L.) producing the Cry1Ac and Cry2Ab2 proteins.
abstract: Bollgard II cotton event 15985 producing the Cry1Ac and Cry2Ab2 proteins has been developed by genetic modification to broaden the spectrum of insects to which the plant is tolerant and to provide an insect resistance management tool to impede the onset of resistance. The purpose of this study was to evaluate the composition and nutrition of Bollgard II cotton, relative to the use for food and animal feed, compared to that of conventional cotton varieties. Compositional analyses were conducted to measure proximate, fiber, amino acid, fatty acid, gossypol, and mineral contents of cottonseed from a total of 14 U.S. field sites over two years. Compositional analysis results showed that the cottonseed and cottonseed oil from Bollgard II cotton were comparable in their composition to those of the conventional control cotton line and other commercial varieties. The composition data are supported by nutritional safety studies conducted with dairy cows, catfish, and quail. Results from these studies showed that Bollgard II performed similarly to the conventional control cotton varieties. These data demonstrate that Bollgard II cotton is compositionally and nutritionally equivalent to conventional cotton varieties. These data support the conclusion that Bollgard II cotton is as safe and nutritious as conventional cotton for food and feed use.
authors.affiliation: Monsanto Company, 800 North Lindbergh Boulevard, St. Louis, Missouri 63167, USA.
authors.forename: Kathryn A
authors.initials: KA
authors.lastname: Hamilton
authors.forename: Paul D
authors.initials: PD
authors.lastname: Pyla
authors.forename: Matthew
authors.initials: M
authors.lastname: Breeze
authors.forename: Tammy
authors.initials: T
authors.lastname: Olson
authors.forename: Menghe
authors.initials: M
authors.lastname: Li
authors.forename: Edwin
authors.initials: E
authors.lastname: Robinson
authors.forename: Sean P
authors.initials: SP
authors.lastname: Gallagher
authors.forename: Roy
authors.initials: R
authors.lastname: Sorbet
authors.forename: Yin
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000821:Animal Feed; D000818:Animals; D000083722:Bacillus thuringiensis Toxins; D001426:Bacterial Proteins / Q000235:genetics*; D001427:Bacterial Toxins / Q000235:genetics*; D002417:Cattle; D003369:Cottonseed Oil / Q000737:chemistry*; D004043:Dietary Fiber / Q000032:analysis; D004731:Endotoxins / Q000235:genetics*; D005227:Fatty Acids / Q000032:analysis; D003368:Gossypium / Q000737:chemistry / Q000235:genetics*; D006072:Gossypol / Q000032:analysis; D006460:Hemolysin Proteins; D007059:Ictaluridae; D008903:Minerals / Q000032:analysis; D030821:Plants, Genetically Modified / Q000737:chemistry / Q000235:genetics*; D011784:Quail
chemical_list: D000596:Amino Acids; D000083722:Bacillus thuringiensis Toxins; D001426:Bacterial Proteins; D001427:Bacterial Toxins; D003369:Cottonseed Oil; D004043:Dietary Fiber; D004731:Endotoxins; D005227:Fatty Acids; D006460:Hemolysin Proteins; D008903:Minerals; C030956:insecticidal crystal protein, Bacillus Thuringiensis; D006072:Gossypol