title: [Cochleovestibular syndromes in vertebrobasilar insufficiency].
abstract: The study aimed at (1) identification of the main vestibulometric characteristics of peripheral cochleovestibular syndrome caused by arterial hypertension, atherosclerosis and vegetative vascular dysfunction, (2) elucidation of the pathogenic peculiarities of its formation and (3) evaluation of therapeutic efficacy of betaserc in peripheral vertigo. Eighty-five patients with peripheral cochleovestibular syndrome (PCVS) were studied. On the base of the data of ultrasonic examination of major cranial arteries, arterial blood pressure, central hemodynamics and structural cerebral changes, it is shown that abnormalities of vertebrobasilar system play an important role in PCVS development. Stenosis of spinal and internal carotid arteries was found in a limited number of cases. A conclusion is made on involvment of hemodynamic mechanism of blood circulation insufficiency in the inner ear at microcirculating level in ischemic PCVS pathogenesis. A study of the structural cerebral changes revealed that PCVS were not accompanied by the ischemic foci in the brain. Pharmacotherapy of peripheral vertigo of vascular etiology is based on the right choice of the drugs optimizing blood circulation in combination with vestibulolytics. Therapeutic efficacy of 2-month betaserc course in peripheral vertigo has been proved.
authors.forename: N S
authors.initials: NS
authors.lastname: Alekseeva
mesh_terms: D000328:Adult; D000368:Aged; D001301:Audiometry, Pure-Tone; D002150:Caloric Tests; D003051:Cochlea / Q000503:physiopathology*; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D014715:Vertebrobasilar Insufficiency / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology*; D014717:Vertigo / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D015837:Vestibular Diseases / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology*