title: Genetic testing in hereditary melanoma.
abstract: Advances in our understanding of molecular genetics bring about unique challenges in our ability to practice molecular medicine. With the availability of commercial testing for various genetic cancer syndromes, including hereditary melanoma, specific issues regarding its use and limitations require attention before full translation of this tool into the clinical setting.
authors.affiliation: Wellman Center for Photomedicine, Department of Dermatology, Boston, Massachusetts, USA.
authors.forename: Hensin
authors.initials: H
authors.lastname: Tsao
authors.forename: Kristin
authors.initials: K
authors.lastname: Niendorf
mesh_terms: D051358:Cyclin-Dependent Kinase 4; D018844:Cyclin-Dependent Kinases / Q000235:genetics; D019942:Genes, p16 / Q000502:physiology; D020022:Genetic Predisposition to Disease; D005821:Genetic Techniques; D005820:Genetic Testing; D006801:Humans; D008545:Melanoma / Q000235:genetics*; D009154:Mutation; D011518:Proto-Oncogene Proteins / Q000235:genetics; D012878:Skin Neoplasms / Q000235:genetics*
chemical_list: D011518:Proto-Oncogene Proteins; C495900:CDK4 protein, human; D051358:Cyclin-Dependent Kinase 4; D018844:Cyclin-Dependent Kinases