title: Box-Cox transformation of left-censored data with application to the analysis of coronary artery calcification and pharmacokinetic data.
abstract: Box-Cox transformation is investigated for regression models for left-censored data. Examples are provided using coronary calcification data from the Multi-Ethnic Study of Atherosclerosis and pharmacokinetic data of a nicotine nasal spray.
authors.affiliation: Collaborative Health Studies Coordinating Center, University of Washington, Box 354922, Building 29, Suite 310, 6200 NE 74th Street, Seattle, WA 98115-8160, USA.
authors.forename: Cong
authors.initials: C
authors.lastname: Han
authors.forename: Richard
authors.initials: R
authors.lastname: Kronmal
mesh_terms: D000281:Administration, Intranasal; D000368:Aged; D001699:Biometry; D002114:Calcinosis / Q000473:pathology; D003331:Coronary Vessels / Q000473:pathology; D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D009538:Nicotine / Q000008:administration & dosage / Q000493:pharmacokinetics; D016016:Proportional Hazards Models; D012044:Regression Analysis
chemical_list: D009538:Nicotine