title: Selective lithiation of 4-(1H-1-pyrrolyl)pyridine. access to new electron-releasing ligands.
abstract: The first lithiation of 4-(1H-1-pyrrolyl)pyridine has been realized. The use of BuLi-containing lithium aggregates induced the selective pyridine ring functionalization by taking advantage of the electron-donor effect of the pyrrole nucleus. Opportune substituents were introduced alpha to the pyridine nitrogen leading to new electron-enriched pyridylphosphine, bipyridine, and terpyridine ligands.
authors.affiliation: Synthèse Organométallique et Réactivité, UMR CNRS 7565, Université Henri Poincaré, Boulevard des Aiguillettes, 54506 Vandoeuvre-lès-Nancy, France.
authors.forename: David
authors.initials: D
authors.lastname: Martineau
authors.forename: Philippe
authors.initials: P
authors.lastname: Gros
authors.forename: Yves
authors.initials: Y
authors.lastname: Fort