title: [Genetic amniocentesis--characteristic of patients, indications, outcomes, complications].
abstract: The indications, outcomes and complications of genetic amniocentesis in a group of 358 women were undeped. The most frequent indication for amniocentesis was maternal age over 35 years. Chromosomal abnormalities were identified in 21 cases (5.8%)--most of them were chromosomal inversions. There were no neural tube defects. In 6 (1.6%) cases the cell culture of amniotic fluid was unsuccessful. The level of alpha-fetoprotein was lower in fetuses with chromosomal abnormalities. 2 (0.5%) patients lost pregnancy after procedure, 4 (1.1%) had amniotic fluid leakage and 1 (0.2%) had pain in hypogastrium after amniocentesis.
authors.affiliation: II Katedra i Klinika Połoznictwa i Ginekologii AM w Warszawie.
authors.forename: Paweł
authors.initials: P
authors.lastname: Milewczyk
authors.forename: Tomasz
authors.initials: T
authors.lastname: Lipiński
authors.forename: Anita
authors.initials: A
authors.lastname: Hamela-Olkowska
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Jalinik
authors.forename: Roman
authors.initials: R
authors.lastname: Szczecina
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Czajkowski
authors.forename: Jacek
authors.initials: J
authors.lastname: Zaremba
mesh_terms: D000328:Adult; D000649:Amniocentesis / Q000009:adverse effects; D002869:Chromosome Aberrations; D005260:Female; D005838:Genotype; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D012189:Retrospective Studies; D000509:alpha-Fetoproteins / Q000378:metabolism
chemical_list: D000509:alpha-Fetoproteins