title: [Umbilical metastasis (Sister Mary Joseph's nodule) diagnosed by fine-needle aspiration].
abstract: Sister Mary Joseph's nodule is the eponym for metastatic involvement of the umbilicus. This less common entity is the sign of disseminated malignant disease, mainly of digestive and gynecologic origin, and is associated with a poor prognosis. A case of Sister Mary Joseph's nodule in a 76-year-old woman in whom the umbilical metastasis was the first sign of malignant disease in presented. The diagnosis of metastatic adenocarcinoma was established by fine needle aspiration cytology of the umbilical nodule. Radiological and ultrasonographic investigation disclosed carcinoma of the gallbladder with pancreas, stomach, and colon invasion as well as peritoneal dissemination. The diagnosis was confirmed by exploratory laparatomy and histological examination of the excised umbilical nodule.
authors.affiliation: Vojnomedicinska akademija, ZPSM-Institut za patologiju, Beograd, Srbija i Crna Gora. zeljkat@sezampro.yu
authors.forename: Zeljka
authors.initials: Z
authors.lastname: Tatomirović
authors.forename: Radojka
authors.initials: R
authors.lastname: Bokun
authors.forename: Vesna
authors.initials: V
authors.lastname: Skuletić
authors.forename: Srbislav
authors.initials: S
authors.lastname: Ilić
authors.forename: Branka
authors.initials: B
authors.lastname: Roganović
authors.forename: Dragan
authors.initials: D
authors.lastname: Milutinović
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000556:secondary*; D000368:Aged; D044963:Biopsy, Fine-Needle; D005260:Female; D005706:Gallbladder Neoplasms / Q000473:pathology*; D006801:Humans; D014472:Umbilicus