title: Selective synthesis of alpha,beta-unsaturated ketones by dibutyltin dimethoxide-catalyzed condensation of aldehydes with alkenyl trichloroacetates.
abstract: Various alpha,beta-unsaturated ketones were stereoselectively synthesized in high yields up to 94% by a condensation reaction between alkenyl trichloroacetates and aldehydes using dibutyltin dimethoxide as a catalyst in the presence of methanol. This process is superior to the classical Claisen-Schmidt condensation with respect to mildness of the base catalyst and product selectivity.
authors.affiliation: Department of Chemistry, Faculty of Science, Chiba University, Inage, Chiba 263-8522, Japan. ayanagi@faculty.chiba-u.jp
authors.forename: Akira
authors.initials: A
authors.lastname: Yanagisawa
authors.forename: Riku
authors.initials: R
authors.lastname: Goudu
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Arai