[Clinical analysis of multiple organ dysfunction syndrome in patients suffering from SARS].
OBJECTIVE
To analyze the features of organ dysfunction in severe acute respiratory syndrome (SARS) and the factors inducing multiple organ dysfunction syndrome (MODS) in these patients.


METHODS
The clinical data of 135 SARS patients and 13 patients with severe SARS complicated by MODS were studied retrospectively.


RESULTS
SARS could result in organ dysfunction. Its incidence rate was high, the patients' condition was severe, and the mortality was higher. SARS could end in MODS and the mortality was 92.3x. The main dysfunctioning organs were the lung (76.9x), the immune system (92.3x), the cardiovascular system (30.8x), the blood system (61.5x), the liver (38.5x), and the kidney (53.8x).


CONCLUSIONS
Dysfunction of organs are closely correlated with prognosis of SARS. The causes of MODS in SARS are probably injury to the immune system and systemic inflammatory response syndrome.
Yin
Cheng-hong
CH
Beijing Friendship Hospital, Affiliated to Capital University of Medical Sciences, Beijing 100050, China.
Wang
Chao
C
Tang
Zhe
Z
Wen
Yan
Y
Zhang
Shu-wen
SW
Wang
Bao-en
BE
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology*; D012189:Retrospective Studies; D045169:Severe Acute Respiratory Syndrome / Q000150:complications*; D055815:Young Adult