title: Synthesis of 1,1,4,4-tetrabromo-2-butenes and related compounds via desilylation-bromination of silylated 1,3-butadiene derivatives.
abstract: The combination of zirconocene-mediated coupling of silylated alkynes with a protonation-desilylation or bromination-desilylation process afforded otherwise unavailable butadiene derivatives. When (E,E)-2,3-dialkyl-1,4-bis(trimethylsilyl)-1,3-butadienes were treated with 3 equiv of Br(2) in CH(2)Cl(2), (E)-2,3-dialkyl-1,1,4,4-tetrabromo-2-butenes were obtained in excellent yields with perfect stereoselectivity.
authors.affiliation: Peking University-Hokkaido University Joint Lab, College of Chemistry, Peking University, Beijing 100871, China.
authors.forename: Zhenfeng
authors.initials: Z
authors.lastname: Xi
authors.forename: Xiaozhong
authors.initials: X
authors.lastname: Liu
authors.forename: Jianming
authors.initials: J
authors.lastname: Lu
authors.forename: Fengyu
authors.initials: F
authors.lastname: Bao
authors.forename: Hongtao
authors.initials: H
authors.lastname: Fan
authors.forename: Zhiping
authors.initials: Z
authors.lastname: Li
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Takahashi