Randomized, controlled trial of priming with 10,000 IU versus 20,000 IU of human chorionic gonadotropin in women with polycystic ovary syndrome who are undergoing in vitro maturation.
Preretrieval priming with 10,000 IU hCG can improve oocyte maturation rates in vitro for women undergoing in vivo maturation treatment, though the optimum dose is unknown. This prospective, randomized, controlled trial demonstrated no improvement in oocyte maturation rates with 20,000 IU of hCG compared with 10,000 IU of hCG and therefore no benefit of the higher dose.
Gulekli
Bulent
B
McGill Reproductive Centre, Royal Victoria Hospital, Montreal, Québec, Canada.
Buckett
William M
WM
Chian
Ri-Cheng
RC
Child
Timothy J
TJ
Abdul-Jalil
A Kamal
AK
Tan
Seang Lin
SL
D000328:Adult; D016922:Cellular Senescence / Q000187:drug effects; D006063:Chorionic Gonadotropin / Q000008:administration & dosage* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy* / Q000209:etiology* / Q000503:physiopathology; D009865:Oocytes / Q000187:drug effects; D011085:Polycystic Ovary Syndrome / Q000150:complications*; D011300:Preoperative Care; D020858:Tissue and Organ Harvesting
D006063:Chorionic Gonadotropin