Total synthesis of callipeltoside A.
A convergent total synthesis of cytotoxic marine macrolide callipeltoside A is described. The synthesis highlights two stereoselective [4 + 2] annulations for the preparation of associated pyran rings.
Huang
Hongbing
H
Department of Chemistry and Center for Chemical Methodology and Library Development, 590 Commonwealth Avenue, Boston University, Boston, Massachusetts 02215, USA.
Panek
James S
JS
D018942:Macrolides / Q000138:chemical synthesis*; D013237:Stereoisomerism
D018942:Macrolides; C410329:callipeltoside A