title: Clear cell sarcoma associated with multiple pulmonary metastases with structural and numerical karyotypic changes.
abstract: Cytogenetic analysis was performed on a specimen from a pulmonary metastasis of clear cell sarcoma originated on the right ankle of a 53-year-old Japanese woman. It revealed near-triploid with several numerical changes including abnormalities in the copy number of chromosomes 7, 8, and 22, and structural abnormalities of chromosome 22 and others. This is a minor case which showed the multiple abnormalities of chromosomes in the absence of a t (12;22) translocation.
authors.affiliation: Department of Dermatology and Clinical Research Institute, Hokkaido Cancer Center, Sapporo, Japan. kato@sap-cc.go.jp
authors.forename: N
authors.initials: N
authors.lastname: Kato
authors.forename: O
authors.initials: O
authors.lastname: Mizuno
authors.forename: A
authors.initials: A
authors.lastname: Tamura
authors.forename: Y
authors.initials: Y
authors.lastname: Yamanaka
authors.forename: S
authors.initials: S
authors.lastname: Tanimura
authors.forename: H
authors.initials: H
authors.lastname: Minakawa
mesh_terms: D000842:Ankle; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007621:Karyotyping; D008175:Lung Neoplasms / Q000235:genetics* / Q000556:secondary*; D008875:Middle Aged; D018227:Sarcoma, Clear Cell / Q000235:genetics* / Q000473:pathology / Q000556:secondary*; D012878:Skin Neoplasms / Q000235:genetics / Q000473:pathology