title: Propionibacterium acnes endophthalmitis with bacterial sequestration in a Molteno's implant after cataract extraction.
abstract: OBJECTIVE
  To report a case of Propionibacterium acnes endophthalmitis following uncomplicated cataract extraction with bacterial sequestration in a preexisting Molteno's drainage implant.
  
  
  METHODS
  Interventional case report.
  
  
  METHODS
  A 7-year-old girl with congenital glaucoma and a preexisting Molteno's drainage implant developed anterior nongranulomatous uveitis 4 months following cataract surgery. P. acnes endophthalmitis was diagnosed by polymerase chain reaction, Southern blot, and electron microscopy.
  
  
  RESULTS
  Extraction of the Molteno's implant was required to control the persistent intraocular inflammation and to convert the results of polymerase chain reaction and Southern blot testing of aqueous sample for P. acnes from positive to negative.
  
  
  CONCLUSIONS
  P. acnes may be sequestered in glaucoma implants, potentially requiring implant removal to treat cases of P. acnes endophthalmitis.
authors.affiliation: Department of Ophthalmology, University of California, San Francisco, California, USA.
authors.forename: David A
authors.initials: DA
authors.lastname: Hollander
authors.forename: Emilio M
authors.initials: EM
authors.lastname: Dodds
authors.forename: Silvia B
authors.initials: SB
authors.lastname: Rossetti
authors.forename: Irmgard S
authors.initials: IS
authors.lastname: Wood
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Alvarado
mesh_terms: D001082:Aqueous Humor / Q000382:microbiology; D015139:Blotting, Southern; D002387:Cataract Extraction; D002648:Child; D020878:Device Removal; D009877:Endophthalmitis / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D005260:Female; D005901:Glaucoma / Q000151:congenital / Q000601:surgery; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D019654:Lens Implantation, Intraocular; D018465:Molteno Implants / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D011183:Postoperative Complications; D011425:Propionibacterium acnes / Q000235:genetics / Q000302:isolation & purification* / Q000648:ultrastructure; D014821:Vitrectomy