[Biochemical markers of preterm delivery].
The paper presents the current status of knowledge about pathology of preterm delivery with presentation of biochemical markers diagnostically useful in prediction of this pathology. Infectious cause of preterm delivery and usefulness of infection diagnostic markers in it's prediction are discussed. Diagnostic potential of immunological inflammatory markers such as IL-6, TNF-alfa and fibronectin and oestriol are emphasised in the context of recently published data. The present status of knowledge doesn't allow for pointing of the most sensitive and specific single predictor of preterm delivery. The most promising are multi-marker investigations performed in pregnancy with risk factors.
Leszczyńska-Gorzelak
Bozena
B
Katedra i Klinika Połoznictwa i Perinatologii, Akademii Medycznej w Lublinie.
Poniedziałek-Czajkowska
Elzbieta
E
D015415:Biomarkers / Q000097:blood*; D004964:Estriol / Q000097:blood; D005260:Female; D005353:Fibronectins / Q000097:blood; D006801:Humans; D007223:Infant; D015850:Interleukin-6 / Q000097:blood; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood; D011256:Pregnancy Outcome; D047928:Premature Birth / Q000097:blood* / Q000209:etiology; D012307:Risk Factors; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
D015415:Biomarkers; D005353:Fibronectins; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D004964:Estriol