[Application and development of purification in cancer genomics research].
In the study of cancer genomics, a series of purification methods have been invented to collect homogenous cells from heterogeneous cancerated tissue. Tissue microdissection methods, such as manual microdissection, mechanical microdissection, and laser technology, accelerated cancer genomics research. Each method holds both advantage and disadvantage, the selection of methods depends on the demands of study, and the instruments used in study.
Liu
Zhong-Qi
ZQ
Department of Otolaryngology, Xiangya Hospital, Central South University, Changsha, Hunan 410 078, P.R. China.
Tian
Yong-Quan
YQ
D000818:Animals; D002469:Cell Separation / Q000379:methods*; D020732:Cytogenetic Analysis / Q000379:methods; D004210:Dissection / Q000379:methods; D020869:Gene Expression Profiling; D023281:Genomics / Q000379:methods*; D006801:Humans; D007834:Lasers; D042282:Microdissection / Q000295:instrumentation / Q000379:methods*; D009369:Neoplasms / Q000235:genetics* / Q000473:pathology