Age, sex, and reproductive state influence free amino acid concentrations in the fasting elephant seal.
Long-term fasting is a component of northern elephant seal (Mirounga angustirostris) life history requiring physiological adaptations to nitrogen conservation. Plasma free amino acids (FAAs) were determined for five elephant seal pups during the second and eighth weeks of the postweaning fast, six lactating female seals at 4-6 and 25 d postpartum, and seven sexually competitive adult male seals taken midway through the breeding season. Total FAAs declined in lactating females (11%) and pups (30%) with time fasting, but cystine concentration more than doubled in pups while decreasing by approximately 43% in lactating females. Methionine concentration significantly increased (approximately 68%) across lactation in adult females but was low for all classes of seal. Alanine was the most abundant FAA in adult males, and glycine became the dominant FAA in adult females late in lactation. Glutamine dominated the FAAs of weaned pups across the fast. Reductions in total FAAs of weanlings mirrored reductions in protein catabolism, but reductions in total FAAs also occurred in lactating females concomitant with an increase in protein catabolism. Observed variation in FAA concentrations may reflect ontogenetic requirements for certain amino acids in fasting weanlings. Similarly, increases in specific FAA concentrations across lactation may reflect variations in FAA flux resulting from the nutrient demands of lactogenesis.
Houser
Dorian S
DS
Department of Biology, School of Science and Technology, Sonoma State University, 1801 East Cotati Avenue, Rohnert Park, CA, 94928, USA.
Crocker
Daniel E
DE
D000222:Adaptation, Physiological; D000367:Age Factors; D000596:Amino Acids / Q000097:blood*; D000818:Animals; D002140:California; D002852:Chromatography, Ion Exchange; D005215:Fasting / Q000502:physiology; D005260:Female; D007774:Lactation / Q000502:physiology; D008297:Male; D012098:Reproduction / Q000502:physiology*; D046048:Seals, Earless / Q000502:physiology*; D012737:Sex Factors
D000596:Amino Acids