title: [Effects of repeated intraperitoneal CDDP chemotherapy for the prevention of T3 and T4 gastric cancer].
abstract: We studied the significance of repeated intraperitoneal CDDP administration, as adjuvant chemotherapy, for the prevention of T3 and T4 gastric cancer. Fifty-two patients who had been operated as Curability B were divided into the following two groups, and the data on survival rate, median survival time and interval of "free of recurrence" were accumulated and analyzed. Group A consisted of nineteen patients treated with intraperitoneal CDDP administration and oral anticancer drugs. Group B were treated with systemic chemotherapy. Group A was superior to Group B in comparing the analyzed data. These results suggested that repeated intraperitoneal CDDP chemotherapy for the prevention of T3 and T4 advanced gastric cancer would improve survival rate.
authors.affiliation: Dept. of Surgery, Hiroshima City Hospital.
authors.forename: Shuya
authors.initials: S
authors.lastname: Yano
authors.forename: Motoki
authors.initials: M
authors.lastname: Ninomiya
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sasaki
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Umeoka
authors.forename: Masao
authors.initials: M
authors.lastname: Harano
authors.forename: Hideki
authors.initials: H
authors.lastname: Aoki
authors.forename: Tadashi
authors.initials: T
authors.lastname: Onoda
authors.forename: Shigehiro
authors.initials: S
authors.lastname: Shiozaki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ohno
authors.forename: Kenji
authors.initials: K
authors.lastname: Higaki
authors.forename: Norihisa
authors.initials: N
authors.lastname: Takakura
mesh_terms: D000284:Administration, Oral; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002945:Cisplatin / Q000008:administration & dosage*; D018450:Disease Progression; D018572:Disease-Free Survival; D004334:Drug Administration Schedule; D006801:Humans; D007263:Infusions, Parenteral; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000401:mortality
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin