Native valve endocarditis due to coagulase-negative staphylococci: report of 99 episodes from the International Collaboration on Endocarditis Merged Database.
Using a large cohort of patients from the International Collaboration on Endocarditis Merged Database, we compared coagulase-negative staphylococcal (CoNS) native-valve endocarditis (NVE) to NVE caused by more common pathogens. Rates of heart failure and mortality were similar between patients with CoNS NVE and patients with Staphylococcus aureus NVE, but rates for both groups were significantly higher than rates for patients with NVE due to viridans streptococci. These results emphasize the importance of CoNS as a cause of NVE and the potential for serious complications with this infection.
Chu
Vivian H
VH
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA. chu00009@mc.duke.edu
Cabell
Christopher H
CH
Abrutyn
Elias
E
Corey
G Ralph
GR
Hoen
Bruno
B
Miro
Jose M
JM
Olaison
Lars
L
Stryjewski
Martin E
ME
Pappas
Paul
P
Anstrom
Kevin J
KJ
Eykyn
Susannah
S
Habib
Gilbert
G
Benito
Natividad
N
Fowler
Vance G
VG
D000368:Aged; D004697:Endocarditis, Bacterial / Q000453:epidemiology / Q000382:microbiology*; D005260:Female; D006349:Heart Valve Diseases / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000453:epidemiology