Bubble generation in a twisted and bent DNA-like model.
The DNA molecule is modeled by a parabola embedded chain with long-range interactions between twisted base pair dipoles. A mechanism for bubble generation is presented and investigated in two different configurations. Using random normally distributed initial conditions to simulate thermal fluctuations, a relationship between bubble generation, twist and curvature is established. An analytical approach supports the numerical results.
Larsen
P V
PV
Informatics and Mathematical Modelling and Department of Mathematics, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark. p.v.larsen@mat.dtu.dk
Christiansen
P L
PL
Bang
O
O
Archilla
J F R
JF
Gaididei
Yu B
YB