title: Low levels of pregnancy-associated plasma protein-A in asymptomatic women destined for miscarriage.
abstract: In an asymptomatic cohort, serum pregnancy-associated protein-A (PAPP-A) levels among women destined to miscarry were 14% of those seen with ongoing pregnancies. Levels were as low 3 weeks before diagnosis as on the day of diagnosis, suggesting that PAPP-A levels might predict future miscarriage.
authors.affiliation: Department of Obstetrics and Gynaecology, Monash University, Monash Medical Centre, Clayton, Victoria, Australia. Stephen.Tong@med.monash.edu.au
authors.forename: Stephen
authors.initials: S
authors.lastname: Tong
authors.forename: Budi
authors.initials: B
authors.lastname: Marjono
authors.forename: Sheila
authors.initials: S
authors.lastname: Mulvey
authors.forename: Euan M
authors.initials: EM
authors.lastname: Wallace
mesh_terms: D000022:Abortion, Spontaneous / Q000097:blood*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D011237:Predictive Value of Tests; D011247:Pregnancy / Q000097:blood*; D011266:Pregnancy-Associated Plasma Protein-A / Q000172:deficiency*
chemical_list: D011266:Pregnancy-Associated Plasma Protein-A