[Usefulness of F-18-fluorodeoxyglucose positron emission tomography for evaluating the efficacy of transient hepatic arterial chemoembolization for liver metastases of rectal cancer--a case report].
It is pointed out that there can be a discrepancy between the effect diagnosed by radiographic imaging and that by histological examination, when we treat patients with liver metastases of colorectal cancer by a transient hepatic arterial chemoembolization. We report a case of liver metastases of rectal cancer in which F-18-fluorodeoxyglucose positron emission tomography (FDG-PET) was useful for evaluating the therapeutic efficacy for transient hepatic arterial chemoembolization. A 58-year-old man with synchronous liver metastases (H2) of rectal cancer underwent a low anterior resection, a partial hepatectomy, cholecystectomy, and ligation of the gastroduodenal artery. After these operations, the patient received 6 hepatic arterial injections with degradable starch microspheres (300-600 mg), adriamycin (30 mg), and mitomycin C (10 mg) for the remaining metastatic lesion (S7). Although abdominal CT scan revealed a partial response, FDG-PET did not show any abnormal deposits. Hepatic posterior segmentectomy was performed 7 months after the first operation. Histological examination did not show any viable tumor cells in the resected specimen.
Yokoyama
Masaru
M
Dept. of Surgery, Saitama Medical Center, Saitama Medical School.
Ishida
Hideyuki
H
Takeuchi
Ikuya
I
Okada
Norimichi
N
Nakada
Hiroshi
H
Ohsawa
Tomonori
T
Ozawa
Fumiaki
F
Hoshino
Takanobu
T
Hashimoto
Daijyo
D
D016461:Chemoembolization, Therapeutic; D002763:Cholecystectomy; D004317:Doxorubicin / Q000008:administration & dosage; D019788:Fluorodeoxyglucose F18; D006498:Hepatectomy; D006499:Hepatic Artery; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy*; D008297:Male; D008863:Microspheres; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D049268:Positron-Emission Tomography; D012004:Rectal Neoplasms / Q000473:pathology*; D013213:Starch / Q000008:administration & dosage
D019788:Fluorodeoxyglucose F18; D016685:Mitomycin; D004317:Doxorubicin; D013213:Starch