The rationale for low-dose hormonal therapy.
A trend in hormonal therapy has been to use a lower dose. The justification for this approach based on both efficacy and safety is presented.
Lobo
Rogerio A
RA
Columbia University's College of Physicians and Surgeons, 622 West 168 Street, 16th floor, New York, NY 10032, USA. ra135@columbia.edu
D001943:Breast Neoplasms / Q000453:epidemiology; D003327:Coronary Disease / Q000517:prevention & control; D004305:Dose-Response Relationship, Drug; D015914:Estrogen Replacement Therapy / Q000009:adverse effects / Q000379:methods*; D004967:Estrogens / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D019584:Hot Flashes; D006801:Humans; D008593:Menopause; D015663:Osteoporosis, Postmenopausal / Q000517:prevention & control; D011372:Progestins / Q000008:administration & dosage
D004967:Estrogens; D011372:Progestins