Use of stereotactic intensity-modulated radiotherapy in thyroid-related ophthalmopathy. Case report.
Thyroid-related ophthalmopathy (TRO), a debilitating condition involving a range of visual and orbital symptoms, occurs in up to 40% of patients with Graves disease. The goals of treatment include correcting thyroid dysfunction, relieving ocular pain, preserving vision, and improving cosmetic appearance. Options for therapy include symptomatic treatment, glucocorticoid medication, radiation therapy, and surgery. Traditional radiation treatment uses small opposed bilateral fields consisting of retrobulbar volumes and customized blocks to shield periorbital structures. The combination of intensity-modulated radiotherapy (IMRT) and stereotactic technology facilitates the administration of radiation to patients suffering from TRO and provides greater safety and efficacy than traditional treatment. The authors present the case of a patient with severe TRO whose symptoms resolved rapidly after treatment with stereotactic IMRT. The outcome in this case supports stereotactic IMRT as an effective treatment option for patients with TRO who also undergo radiation therapy.
Espinoza
Salvador
S
Departments of Radiation Oncology, New York Medical College, Valhalla, New York, USA.
Saboori
Mehran
M
Forman
Scott
S
Moorthy
Chitti R
CR
Benzil
Deborah L
DL
D000328:Adult; D005260:Female; D006111:Graves Disease / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D012720:Severity of Illness Index; D013238:Stereotaxic Techniques; D016896:Treatment Outcome