Sequence variation in the gene encoding the major capsid protein of Korean fish iridoviruses.
Ten iridoviruses were isolated from cultured fish from various regions in Korea; 7 from rock bream, 1 from red sea bream, 1 from sea bass, and 1 from rockfish. The full open-reading frame (ORF) encoding the major capsid protein (MCP) (1362 bp) from ten iridoviruses were sequenced and the nucleotide sequences were phylogenetically analyzed. Phylogenetic analysis revealed that the ten Korean isolates were classified into one cluster. However, their sequences were not identical and, based on the nucleotide sequence variation, they could be further divided into two subgroups. While nine Korean isolates were similar to the Japanese isolate red sea bream iridovirus (RSIV), one isolate was distinct from other iridovirus isolates. These results suggest that a diversity of iridoviruses exist in Korea and that a new variant strain has emerged.
Do
J W
JW
Pathology Division, National Fisheries Research and Development Institute, Busan, Korea.
Cha
S J
SJ
Kim
J S
JS
An
E J
EJ
Park
M S
MS
Kim
J W
JW
Kim
Y C
YC
Park
M A
MA
Park
J W
JW
D000595:Amino Acid Sequence; D000818:Animals; D036022:Capsid Proteins / Q000235:genetics*; D004266:DNA Virus Infections / Q000662:veterinary* / Q000821:virology; D005393:Fish Diseases / Q000821:virology*; D005399:Fishes; D005814:Genes, Viral; D014644:Genetic Variation; D007497:Iridoviridae / Q000235:genetics* / Q000302:isolation & purification; D007723:Korea; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D010802:Phylogeny; D016415:Sequence Alignment
D036022:Capsid Proteins