title: Intracellular membrane transport systems in Trypanosoma brucei.
abstract: Trypanosomes belong to the order kinetoplastida, an early diverging group of organisms in the eukaryotic lineage. The principal reasons for interest in these organisms are twofold; they provide a superb distant triangulation point from which to assess global features of eukaryotic biology and, more importantly, they are representative of a number of pathogenic parasitic protozoa with a huge public health impact --Trypanosoma brucei, T. cruzi and Leishmania spp. Recent advances in the study of intracellular transport in T. brucei have been considerable, and a fuller picture of the complexity, function and role that the endomembrane system plays in trypanosomes is finally emerging.
authors.affiliation: Department of Biological Sciences, Imperial College, London, UK. mfield@mac.com
authors.forename: Mark C
authors.initials: MC
authors.lastname: Field
authors.forename: Mark
authors.initials: M
authors.lastname: Carrington
mesh_terms: D000818:Animals; D004705:Endocytosis / Q000502:physiology; D005089:Exocytosis / Q000502:physiology; D007425:Intracellular Membranes / Q000502:physiology*; D021381:Protein Transport / Q000502:physiology; D014345:Trypanosoma / Q000502:physiology*