Malignant peripheral nerve sheath tumour metastatic to the orbit.
OBJECTIVE
To present a case of malignant peripheral nerve sheath tumour (MPNST) metastatic to the orbit.


RESULTS
The authors describe a 29-year-old woman with disseminated MPNST who presented with acute right orbital inflammation. Computerized tomography revealed a superolateral mass with a central radiolucent area. At biopsy, the mass was primarily subperiosteal and histology showed a spindle cell, S100-positive MPNST consistent with the primary tumour.


CONCLUSIONS
This is the second reported case of MPNST metastatic to the orbit and illustrates that an inflammatory presentation is possible in this aggressive malignancy.
Selva
Dinesh
D
Department of Ophthalmology, University of British Columbia and the Vancouver General Hospital, Vancouver, Canada.
Davis
Garry
G
Dodd
Tom
T
Rootman
Jack
J
D000328:Adult; D002443:Ceftriaxone / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D018317:Nerve Sheath Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary*; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary*; D012983:Soft Tissue Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed
D002443:Ceftriaxone