title: Determination of cobalt in pharmaceutical products.
abstract: The aim of this paper is to determine the content of cobalt in pharmaceutical products (B(12) vitamin powder, B(12) ampoules, Centrum, Spectrum ABC and Optima Forte) by spectrometric (FAAS, GFAAS and ICP-AES) and electrometric (AdSV) analytical techniques. The samples (approximately 0.5g) were treated with a mixture of 6mL HNO(3) and 1mL H(2)O(2) in the microwave oven. Due to the matrix effects the method of standard addition is preferred. The validity of the methods was tested by recovery studies of standard addition and results were found to be satisfactory.
authors.affiliation: Department of Analytical Chemistry, Faculty of Chemistry, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest-3, Romania. anca_stoica2003@yahoo.com
authors.forename: Anca-Iulia
authors.initials: AI
authors.lastname: Stoica
authors.forename: Mariana
authors.initials: M
authors.lastname: Peltea
authors.forename: George-Emil
authors.initials: GE
authors.lastname: Baiulescu
authors.forename: Mihai
authors.initials: M
authors.lastname: Ionica
mesh_terms: D003035:Cobalt / Q000032:analysis*; D004364:Pharmaceutical Preparations / Q000032:analysis*; D014805:Vitamin B 12 / Q000032:analysis
chemical_list: D004364:Pharmaceutical Preparations; D003035:Cobalt; D014805:Vitamin B 12