title: Native valve endocarditis due to coagulase-negative staphylococci: report of 99 episodes from the International Collaboration on Endocarditis Merged Database.
abstract: Using a large cohort of patients from the International Collaboration on Endocarditis Merged Database, we compared coagulase-negative staphylococcal (CoNS) native-valve endocarditis (NVE) to NVE caused by more common pathogens. Rates of heart failure and mortality were similar between patients with CoNS NVE and patients with Staphylococcus aureus NVE, but rates for both groups were significantly higher than rates for patients with NVE due to viridans streptococci. These results emphasize the importance of CoNS as a cause of NVE and the potential for serious complications with this infection.
authors.affiliation: Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA. chu00009@mc.duke.edu
authors.forename: Vivian H
authors.initials: VH
authors.lastname: Chu
authors.forename: Christopher H
authors.initials: CH
authors.lastname: Cabell
authors.forename: Elias
authors.initials: E
authors.lastname: Abrutyn
authors.forename: G Ralph
authors.initials: GR
authors.lastname: Corey
authors.forename: Bruno
authors.initials: B
authors.lastname: Hoen
authors.forename: Jose M
authors.initials: JM
authors.lastname: Miro
authors.forename: Lars
authors.initials: L
authors.lastname: Olaison
authors.forename: Martin E
authors.initials: ME
authors.lastname: Stryjewski
authors.forename: Paul
authors.initials: P
authors.lastname: Pappas
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Anstrom
authors.forename: Susannah
authors.initials: S
authors.lastname: Eykyn
authors.forename: Gilbert
authors.initials: G
authors.lastname: Habib
authors.forename: Natividad
authors.initials: N
authors.lastname: Benito
authors.forename: Vance G
authors.initials: VG
authors.lastname: Fowler
mesh_terms: D000368:Aged; D004697:Endocarditis, Bacterial / Q000453:epidemiology / Q000382:microbiology*; D005260:Female; D006349:Heart Valve Diseases / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000453:epidemiology