title: Airborne allergy to sunflower seed.
abstract: BACKGROUND
  There is increasing evidence that bird fanciers may develop airborne allergies to unusual allergens.
  
  
  OBJECTIVE
  To detect the allergen source in a bird fancier with a history of asthma associated with bird cage cleaning activities and with contact with a Brazil parrot.
  
  
  METHODS
  SPT with a large series of both airborne and food allergens were carried out. IgE reactivity to allergens causing wheal and flare reactions was confirmed by in-vitro investigations including ELISA/ELISA inhibition and immunoblot analysis.
  
  
  RESULTS
  Strong skin reactivity to sunflower seed was observed. Immunoblot analysis showed IgE reactivity to low m.w. proteins, most probably 2S albumin, and ELISA inhibition studies showed the absence of cross-reactivity to mustard.
  
  
  CONCLUSIONS
  Sunflower seed dust may sensitize patients via the respiratory tract. Differently from previously reported cases of sunflower seed allergy, no cross-reactivity to 2S albumin from botanically unrelated seeds was found.
authors.affiliation: Ambulatorio di Allergologia, Clinica San Carlo, Paderno Dugnano (MI), Italy. r.asero@libero.it
authors.forename: R
authors.initials: R
authors.lastname: Asero
authors.forename: G
authors.initials: G
authors.lastname: Mistrello
authors.forename: D
authors.initials: D
authors.lastname: Roncarolo
authors.forename: S
authors.initials: S
authors.lastname: Amato
mesh_terms: D000485:Allergens / Q000276:immunology*; D001249:Asthma / Q000209:etiology* / Q000503:physiopathology; D004781:Environmental Exposure; D004797:Enzyme-Linked Immunosorbent Assay; D006368:Helianthus / Q000276:immunology*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000175:diagnosis / Q000209:etiology*; D007073:Immunoglobulin E / Q000276:immunology; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D012882:Skin Tests
chemical_list: D000485:Allergens; D007073:Immunoglobulin E