Kinetochores: if you build it, they will come.
Successful mitosis depends critically on the segregation of chromosomes by kinetochore microtubules. A recent paper describes a conserved protein network from Caenorhabditis elegans that is composed of three classes of molecules, each of which contributes uniquely to the building of the kinetochore-microtubule attachment site.
DeLuca
Jennifer G
JG
University of North Carolina, Department of Biology, 607 Fordham Hall, CB#3280, Chapel Hill, North Carolina 27599-3280, USA.
Salmon
E D
ED
D000818:Animals; D017173:Caenorhabditis elegans; D020090:Chromosome Segregation / Q000502:physiology*; D018386:Kinetochores / Q000378:metabolism*; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D008956:Models, Chemical
D008869:Microtubule-Associated Proteins