title: Solitary infantile myofibroma compromising the airway.
abstract: Infantile myofibromatosis is an uncommon and benign condition presenting in the neonatal period. It is self-limiting disease that may present as a localised or generalised process. Various examples of this entity have been reported in the literature. This report describes a neonate with a rapidly growing oropharyngeal lesion obstructing the airway that had the typical histological features of an infantile myofibroma. This case report highlights that a solitary myofibroma may be incredibly extensive making complete excision impossible and can be particularly challenging to manage in terms of airway stabilisation.
authors.affiliation: Department of Otolaryngology, St. George's Hospital, London, UK. nnekaeze@yahoo.co.uk
authors.forename: N
authors.initials: N
authors.lastname: Eze
authors.forename: L
authors.initials: L
authors.lastname: Pitkin
authors.forename: S
authors.initials: S
authors.lastname: Crowley
authors.forename: P
authors.initials: P
authors.lastname: Wilson
authors.forename: H
authors.initials: H
authors.lastname: Daya
mesh_terms: D000402:Airway Obstruction / Q000209:etiology*; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D020680:Bronchoscopes; D003609:Dactinomycin / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D020704:Laryngoscopes; D008279:Magnetic Resonance Imaging; D008297:Male; D047708:Myofibroma / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D013517:Otorhinolaryngologic Surgical Procedures; D016896:Treatment Outcome; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D003609:Dactinomycin; D014750:Vincristine