Morphometrical analysis of the kidney from nonobese diabetic (NOD) mice in the non-diabetic stage.
The kidneys of non-diabetic NOD and wild type ICR mice were examined morphometrically at 3 and 6 months of age. Kidney weights and diameter of renal corpuscles of non-diabetic NOD mice were less than those of ICR mice. No lesions were observed in glomeruli or uriniferous tubules. Renin-positive areas were more common in NOD mice than in ICR mice, but no differences were detected in the Western blot analyses.
Maeda
Michie
M
Department of Veterinary Anatomy, Faculty of Agriculture, Kagoshima University, Japan.
Yabuki
Akira
A
Matsumoto
Mitsuharu
M
Taniguchi
Kazuyuki
K
Suzuki
Syusaku
S
D000367:Age Factors; D000818:Animals; D015153:Blotting, Western; D001837:Body Weights and Measures; D007150:Immunohistochemistry; D007668:Kidney / Q000033:anatomy & histology*; D051379:Mice; D016688:Mice, Inbred NOD / Q000033:anatomy & histology*; D009929:Organ Size