title: Nucleocapsid protein as early diagnostic marker for SARS.
abstract: Serum samples from 317 patients with patients with severe acute respiratory syndrome (SARS) were tested for the nucleocapsid (N) protein of SARS-associated coronavirus, with sensitivities of 94% and 78% for the first 5 days and 6-10 days after onset, respectively. The specificity was 99.9%. N protein can be used as an early diagnostic maker for SARS.
authors.affiliation: Center of Laboratory, Zhujiang Hospital, First Military Medical University, Guangzhou, People's Republic of China. linche@pub.guangzhou.gd.cn
authors.forename: Xiao-Yan
authors.initials: XY
authors.lastname: Che
authors.forename: Wei
authors.initials: W
authors.lastname: Hao
authors.forename: Yadi
authors.initials: Y
authors.lastname: Wang
authors.forename: Biao
authors.initials: B
authors.lastname: Di
authors.forename: Kai
authors.initials: K
authors.lastname: Yin
authors.forename: Yin-Chao
authors.initials: YC
authors.lastname: Xu
authors.forename: Chang-Sen
authors.initials: CS
authors.lastname: Feng
authors.forename: Zhuo-Yue
authors.initials: ZY
authors.lastname: Wan
authors.forename: Vincent C C
authors.initials: VC
authors.lastname: Cheng
authors.forename: Kwok-Yung
authors.initials: KY
authors.lastname: Yuen
mesh_terms: D000914:Antibodies, Viral / Q000097:blood; D015415:Biomarkers; D006801:Humans; D019590:Nucleocapsid Proteins / Q000097:blood*; D045473:Severe acute respiratory syndrome-related coronavirus / Q000302:isolation & purification*; D045169:Severe Acute Respiratory Syndrome / Q000175:diagnosis*; D013997:Time Factors
chemical_list: D000914:Antibodies, Viral; D015415:Biomarkers; D019590:Nucleocapsid Proteins