[Pseudomonas sepsis with ecthyma gangrenosum in an acute myeloid leukemia patient].
A 56-year-old woman with acute myeloid leukemia had two rapidly growing necrotizing nodules with ulcer formation on her head after the first course of consolidation therapy. Clinical features corresponding to sepsis (e.g., fever) appeared following the development of the skin lesion. Pseudomonas aeruginosa was isolated from the blood as well as pus of the lesion. Based on these findings, a diagnosis of ecthyma gangrenosum was made. Treatment with ciprofloxacin and gamma-globulin dramatically improved the patient's clinical features. Since Pseudomonas sepsis with ecthyma gangrenosum is associated with a high mortality rate, it is important to start immediate treatment with appropriate antibiotics.
Obara
Yoko
Y
Division of Hematology, Department of Medicine, Jichi Medical School.
Nagai
Tadashi
T
Mori
Masaki
M
Ohmine
Ken
K
Toshima
Masaki
M
Komatsu
Norio
N
Ozawa
Keiya
K
D000890:Anti-Infective Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D003561:Cytarabine / Q000008:administration & dosage / Q000009:adverse effects; D004473:Ecthyma / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D015255:Idarubicin / Q000008:administration & dosage / Q000009:adverse effects; D016867:Immunocompromised Host; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000188:drug therapy; D008875:Middle Aged; D008942:Mitoxantrone / Q000008:administration & dosage / Q000009:adverse effects; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000209:etiology*; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D012535:Scalp; D018805:Sepsis / Q000188:drug therapy / Q000209:etiology*; D016896:Treatment Outcome; D005719:gamma-Globulins / Q000627:therapeutic use
D000890:Anti-Infective Agents; D005719:gamma-Globulins; D003561:Cytarabine; D002939:Ciprofloxacin; D008942:Mitoxantrone; D015255:Idarubicin