[CPT-11 hepatic arterial infusion chemotherapy for metastatic liver tumor from gastric cancer].
We have experienced a case of gastric cancer with multiple liver metastases resistant to combined treatment of TS-1 and CDDP. After the treatment with TS-1 and CDDP, abdominal CT demonstrated a progressive growth of metastatic liver tumor. Administration of CPT-11 (80 mg/body) by a hepatic arterial infusion inhibited the growth of metastatic liver tumor and decreased serum levels of CEA and CA19-9 for several months without a significant adverse side effect.
Nagahama
Takeshi
T
Dept of Surgery, Tokyo Metropolitan Toshima Hospital.
Ando
Masayuki
M
Maruyama
Michio
M
D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage*; D002166:Camptothecin / Q000008:administration & dosage* / Q000031:analogs & derivatives*; D006801:Humans; D007261:Infusions, Intra-Arterial; D000077146:Irinotecan; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D013274:Stomach Neoplasms / Q000473:pathology*
D000972:Antineoplastic Agents, Phytogenic; D000077146:Irinotecan; D002166:Camptothecin