Dairy cream as a phantom material for biexponential diffusion decay.
Commercially available aliquots of dairy cream are shown to have diffusion decay curves characterized by biexponential functions when studied over a wide range of b-factors. The fast and slow diffusion components responsible for the biexponential decay are attributed to water and lipid protons, respectively. The fast diffusion coefficient and relative fast and slow diffusion component fractions obtained from biexponential fits of cream phantoms over a wide range of b-factors up to 3,000 s/mm2 are similar to those obtained previously for brain. The slow diffusion coefficient from lipid protons is smaller than that found in the brain. Overall, however, the results suggest that dairy cream can serve as a widely available phantom material for testing software and hardware components designed to perform quantitative, biexponential diffusion decay studies.
Ababneh
Z
Z
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
Haque
M
M
Maier
S E
SE
Mulkern
R V
RV
D000818:Animals; D040761:Biomimetic Materials / Q000032:analysis / Q000737:chemistry*; D001923:Brain Chemistry; D002417:Cattle; D003611:Dairy Products / Q000032:analysis; D038524:Diffusion Magnetic Resonance Imaging / Q000295:instrumentation* / Q000379:methods*; D008422:Materials Testing; D008892:Milk / Q000737:chemistry*; D019047:Phantoms, Imaging