This little pIgR went to the mucosa.
In this issue, we report the structure of the terminal domain of the polymeric immunoglobulin receptor (pIgR), which mediates the "suicide" transcytosis of multimeric immunoglobulins (IgA, IgM). This assists in reconciling decades of biochemistry, revealing a long-puzzling interaction.
Strong
Roland K
RK
Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA.
D007413:Intestinal Mucosa / Q000378:metabolism*; D008958:Models, Molecular; D011487:Protein Conformation; D019056:Receptors, Polymeric Immunoglobulin / Q000737:chemistry / Q000378:metabolism*
D019056:Receptors, Polymeric Immunoglobulin