title: Hexafluoroacetone as protecting and activating reagent: site-selective functionalization of iminodiacetic acid.
abstract: Hexafluoroacetone was applied as a bidentate protecting and activating agent for the syntheses of RGD-peptide mimetics starting from iminodiacetic acid in solution and on solid phase.
authors.affiliation: Organisch-Chemisches Institut der Universität Leipzig, Leipzig, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Rühl
authors.forename: C
authors.initials: C
authors.lastname: Böttcher
authors.forename: L
authors.initials: L
authors.lastname: Hennig
authors.forename: K
authors.initials: K
authors.lastname: Burger
mesh_terms: D000096:Acetone / Q000031:analogs & derivatives* / Q000737:chemistry*; D001671:Biochemistry / Q000379:methods; D005466:Fluorocarbons / Q000737:chemistry*; D007098:Imino Acids / Q000737:chemistry*; D007202:Indicators and Reagents / Q000737:chemistry; D016023:Integrins / Q000037:antagonists & inhibitors; D018716:Molecular Mimicry; D009842:Oligopeptides / Q000737:chemistry; D019151:Peptide Library; D010455:Peptides / Q000737:chemistry; D006845:Hydrocarbons, Fluorinated
chemical_list: D000096:Acetone; D005466:Fluorocarbons; D007098:Imino Acids; D007202:Indicators and Reagents; D016023:Integrins; D009842:Oligopeptides; D019151:Peptide Library; D010455:Peptides; C047981:arginyl-glycyl-aspartic acid; C017366:hexafluoroacetone; D006845:Hydrocarbons, Fluorinated; C008109:iminodiacetic acid