Imaging takes a quantum leap.
Semiconducting nanocrystals, or quantum dots (QDs), have emerged as a new tool in physiological imaging, combining high brilliance, photostability, broad excitation but very narrow emission spectra, and surface chemistry compatible with biomolecular conjugation. In this review, we demonstrate the power of QDs in diverse applications, including long-term in vivo fluorescence imaging.
Lidke
Diane S
DS
Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, D-37077 Göttingen, Germany. dlidke@gwdg.de
Arndt-Jovin
Donna J
DJ
D000818:Animals; D008856:Microscopy, Fluorescence / Q000379:methods* / Q000639:trends*; D045663:Quantum Dots