title: Alcon CustomCornea wavefront-guided retreatments after laser in situ keratomileusis.
abstract: OBJECTIVE
  To evaluate the outcome of wavefront-guided ablations for the correction of residual myopia and astigmatism after standard laser in situ keratomileusis (LASIK).
  
  
  METHODS
  Twenty nine eyes of 26 patients who underwent wavefront-guided LASIK retreatment with Alcon CustomCornea (Alcon Laboratories Inc, Fort Worth, Tex) were evaluated. Complete ophthalmologic examination, corneal topography, and wavefront measurements were performed. Uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), manifest refraction, and wavefront analysis were evaluated preoperatively, 1 week, 3 months, and 6 months after surgery. Wavefront measurements were assessed using the LADARWave device. Statistical analysis was performed using the McNemar test and percentages of success.
  
  
  RESULTS
  One week postoperatively, UCVA was > or =20/40 in 100% of eyes (> or =20/20 in 31%) and BSCVA was > or =20/40 in 100% (> or =20/20 in 73%). Wavefront analysis showed a decrease in total aberrations, high order aberrations, defocus, coma, spherical aberration, and other terms of higher order aberrations at 1-week follow-up. Three months postoperatively, UCVA was > or =20/40 in 100% of eyes (> or =20/20 in 38%) and BSCVA was > or =20/40 in 100% (> or =20/20 in 81%). Six months postoperatively, UCVA was > or =20/40 in 100% of eyes (> or =20/20 in 60%) and BSCVA was > or =20/40 in 100% (> or =20/20 in 90%). Wavefront analysis showed decrease in total aberration, high order aberration, defocus, coma, and spherical aberration.
  
  
  CONCLUSIONS
  Wavefront-guided LASIK retreatment in post-LASIK eyes represents a good option for laser vision correction. All eyes showed reduction in pre-existing total aberrations. Some high order aberration components decreased in this initial series. Further follow-up is necessary to assess the initial predictability of wavefront-guided LASIK upgrade.
authors.affiliation: Department of Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil. mrchalita@pobox.com
authors.forename: Maria Regina
authors.initials: MR
authors.lastname: Chalita
authors.forename: Meng
authors.initials: M
authors.lastname: Xu
authors.forename: Ronald R
authors.initials: RR
authors.lastname: Krueger
mesh_terms: D000328:Adult; D000368:Aged; D001251:Astigmatism / Q000601:surgery* / Q000628:therapy; D003316:Corneal Diseases / Q000175:diagnosis / Q000601:surgery; D019781:Corneal Topography; D005139:Eyeglasses; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000601:surgery* / Q000628:therapy; D012086:Reoperation; D012189:Retrospective Studies; D016896:Treatment Outcome; D014786:Vision Disorders / Q000175:diagnosis / Q000601:surgery; D014792:Visual Acuity