title: Study of lubricant-induced changes in chronic snorers (SLICCS).
abstract: OBJECTIVE
  The efficacy of many of the noninvasive treatments for snoring has not been evaluated in controlled trials. This paper seeks to evaluate the efficacy of an oil-based spray in the treatment of snoring, in a double-blinded, placebo-controlled, crossover trial using objective acoustic analysis and subjective questionnaires.
  
  
  METHODS
  Participants were randomized to use both oil-based oral spray (treatment) and water-based oral spray (placebo) during a two-night in-home study period. Questionnaires were completed by participant and bed-partner in addition to audio-tape recordings which were analyzed for frequency, duration, and mean energy of snoring.
  
  
  RESULTS
  Greatest snoring rate demonstrated 30% = benefit; 40% = no change; 30% = adverse effect (n = 20). Percent time snoring yielded: 30% benefit; 15% no change; 55% adverse effect (n = 20). Study data results for mean energy were (n = 12): benefit = 17%, no change = 33%, adverse effect = 50%. Bed-partner observations (n = 17) demonstrated 37% = benefit; 38% = no change; 25% = adverse effect.
  
  
  CONCLUSIONS
  Objective and subjective evaluation of the performance of the oil-based Snoreless spray in comparison to placebo demonstrated a lack of efficacy in snoring reduction.
authors.affiliation: Wake Forest University School of Medicine, Winston-Salem, NC 25157, USA.
authors.forename: Rohan C
authors.initials: RC
authors.lastname: Wijewickrama
authors.forename: David
authors.initials: D
authors.lastname: Blalock
authors.forename: James W
authors.initials: JW
authors.lastname: Mims
mesh_terms: D000162:Acoustics / Q000295:instrumentation; D000287:Administration, Topical; D000328:Adult; D002908:Chronic Disease; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008153:Lubrication; D008297:Male; D008875:Middle Aged; D009821:Oils / Q000008:administration & dosage*; D012913:Snoring / Q000175:diagnosis / Q000188:drug therapy*; D013637:Tape Recording; D016896:Treatment Outcome
chemical_list: D009821:Oils