title: [Effect of integrated traditional Chinese and Western medicine therapy on progression of acute renal failure in patients with chronic renal insufficiency: a short-term clinical study].
abstract: OBJECTIVE
  To evaluate the effect of integrated traditional Chinese and Western medicine therapy on the progression of acute renal failure in patients with chronic renal insufficiency.
  
  
  METHODS
  Thirty-two patients with chronic renal insufficiency developed acute renal failure recently were treated with Chinese herbs and western drugs intravenously and clysterizing of Chinese herbs liquid for 30 minutes, and the treatment course was 14 days. Assessment of liver and renal function, blood routine, electrolytes and endogenous creatinine clearance rate (Ccr) was performed before and 2 weeks after the treatment.
  
  
  RESULTS
  The levels of hemoglobin (HB), white blood cell count (WBC) and serum electrolytes showed no significant changes after the treatment. The levels of blood urea nitrogen (BUN) and serum creatinine (SCr) decreased, while the level of Ccr increased significantly (P<0.05) after the treatment. The total effective rate was 65.6%.
  
  
  CONCLUSIONS
  The integrated traditional Chinese and Western medicine therapy can effectively delay the deterioration of renal function in patients with chronic renal insufficiency accompanied by acute renal failure.
authors.affiliation: Department of Nephrology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China. fupeng66@citiz.net
authors.forename: Peng
authors.initials: P
authors.lastname: Fu
authors.forename: Guang
authors.initials: G
authors.lastname: Yu
authors.forename: Xue-Qiang
authors.initials: XQ
authors.lastname: Huang
authors.forename: Jing
authors.initials: J
authors.lastname: Xu
authors.forename: Xiao-Bin
authors.initials: XB
authors.lastname: Mei
authors.forename: Hao
authors.initials: H
authors.lastname: Wu
authors.forename: Wei-Jie
authors.initials: WJ
authors.lastname: Yuan
mesh_terms: D058186:Acute Kidney Injury / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001806:Blood Urea Nitrogen; D003404:Creatinine / Q000097:blood / Q000378:metabolism; D018450:Disease Progression; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000188:drug therapy*; D007677:Kidney Function Tests; D008111:Liver Function Tests; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D028321:Plant Preparations; D011188:Potassium / Q000097:blood / Q000378:metabolism; D012189:Retrospective Studies; D012964:Sodium / Q000097:blood / Q000378:metabolism; D016896:Treatment Outcome
chemical_list: D004365:Drugs, Chinese Herbal; D010936:Plant Extracts; D028321:Plant Preparations; D012964:Sodium; D003404:Creatinine; D011188:Potassium