title: The relationship between iron status and thyroid hormones in adolescents living in an iodine deficient area.
abstract: BACKGROUND
  Iron may be only one of many nutritional factors that influence thyroid hormone metabolism in iodine-deficient areas.
  
  
  OBJECTIVE
  To evaluate the effect of iron status on thyroid hormone profile in adolescents living in a mild iodine-deficient area in Turkey.
  
  
  METHODS
  Three hundred and thirty school-aged children with mean age 14 years were examined.
  
  
  METHODS
  Free triiodothyronine, free tetraiodothyronine and thyrotropin levels were analyzed by chemiluminescent enzyme immunoassay. Hemoglobin and mean corpuscular volume were measured with a Hemocounter. Iron and total iron binding capacity concentration were determined by colorimetric photometric methods. Ferritin level was determined by immunoturbidimetry.
  
  
  RESULTS
  Thyroid hormone levels of the children with anemia were not significantly different compared to children without anemia. No significant correlation was found between thyroid hormones and iron status.
  
  
  CONCLUSIONS
  The thyroid hormone profile was not significantly affected in this area. This survey showed no correlation between iron status and thyroid hormone levels.
authors.affiliation: Department of Biochemistry, Düzce School of Medicine, Abant Izzet Baysal University, Düzce, Turkey. o_yavuz@yahoo.com
authors.forename: Ozlem
authors.initials: O
authors.lastname: Yavuz
authors.forename: Taner
authors.initials: T
authors.lastname: Yavuz
authors.forename: Cemil
authors.initials: C
authors.lastname: Kahraman
authors.forename: Nuray
authors.initials: N
authors.lastname: Yeşildal
authors.forename: Ruveyde
authors.initials: R
authors.lastname: Bundak
mesh_terms: D000293:Adolescent; D000740:Anemia / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D002648:Child; D015897:Comorbidity; D019353:Endemic Diseases / Q000706:statistics & numerical data; D005260:Female; D006043:Goiter, Endemic / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D006454:Hemoglobins; D006801:Humans; D015994:Incidence; D007455:Iodine / Q000172:deficiency; D007501:Iron / Q000097:blood*; D008297:Male; D012016:Reference Values; D013960:Thyroid Function Tests; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood*; D014284:Triiodothyronine / Q000097:blood*; D014421:Turkey / Q000453:epidemiology
chemical_list: D006454:Hemoglobins; D014284:Triiodothyronine; D013972:Thyrotropin; D007455:Iodine; D007501:Iron; D013974:Thyroxine