Novel sesterterpenes from Leucosceptrum canum of nepalese origin.
Two novel sesterterpenoids, leucosesterterpenone (1) and leucosesterlactone (2), with novel skeleta were isolated from the hexane extract of the medicinal plant, Leucosceptrum canum. Their structures were established by the analysis of NMR data and the single-crystal X-ray diffraction of compound 1. Compounds 1 and 2 were found to exhibit activity against prolylendopeptidase (PEP).
Choudhary
Muhammad Iqbal
MI
H. E. J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi 75270, Pakistan.
Ranjit
Rosa
R
Atta-ur-Rahman
Hussain
Sajjad
S
Devkota
Krishna Prasad
KP
Shrestha
Tirtha Maiya
TM
Parvez
Masood
M
D019686:Lamiaceae / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D054830:Sesterterpenes; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification*
D054830:Sesterterpenes; D013729:Terpenes