Comparison of measurement of cross-sectional coronary atherosclerotic plaque and vessel areas by 16-slice multidetector computed tomography versus intravascular ultrasound.
In 26 patients, 16-slice multidetector computed tomography (MDCT) with 0.75-mm collimation and intravascular ultrasound (IVUS) of 1 coronary artery were performed. At 100 sites within the coronary arteries, the measurement of cross-sectional luminal area and, if detectable, the cross-sectional area of atherosclerotic plaque was performed independently with IVUS and MDCT. The mean luminal area (r = 0.92), measured at 100 sites, and plaque area (r = 0.55), measured at 65 sites, were significantly correlated (p <0.001) between MDCT and IVUS. The mean luminal area and mean plaque area were slightly but significantly overestimated with MDCT. MDCT permits the noninvasive measurement of coronary cross-sectional luminal and plaque areas with moderate accuracy.
Moselewski
Fabian
F
Division of Cardiology, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Ropers
Dieter
D
Pohle
Karsten
K
Hoffmann
Udo
U
Ferencik
Maros
M
Chan
Ray C
RC
Cury
Ricardo C
RC
Abbara
Suhny
S
Jang
Ik-Kyung
IK
Brady
Thomas J
TJ
Daniel
Werner G
WG
Achenbach
Stephan
S
D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D018084:Ultrasonography, Interventional