Y chromosome of D. pseudoobscura is not homologous to the ancestral Drosophila Y.
We report a genome-wide search of Y-linked genes in Drosophila pseudoobscura. All six identifiable orthologs of the D. melanogaster Y-linked genes have autosomal inheritance in D. pseudoobscura. Four orthologs were investigated in detail and proved to be Y-linked in D. guanche and D. bifasciata, which shows that less than 18 million years ago the ancestral Drosophila Y chromosome was translocated to an autosome in the D. pseudoobscura lineage. We found 15 genes and pseudogenes in the current Y of D. pseudoobscura, and none are shared with the D. melanogaster Y. Hence, the Y chromosome in the D. pseudoobscura lineage appears to have arisen de novo and is not homologous to the D. melanogaster Y.
Carvalho
Antonio Bernardo
AB
Departamento de Genética, Universidade Federal do Rio de Janeiro, Caixa Postal 68011, CEP 21944-970, Rio de Janeiro, Brazil. bernardo@biologia.ufrj.br
Clark
Andrew G
AG
D000818:Animals; D005075:Biological Evolution; D002875:Chromosomes / Q000235:genetics / Q000502:physiology; D021901:DNA, Intergenic; D004330:Drosophila / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics; D005260:Female; D017344:Genes, Insect; D008040:Genetic Linkage; D016678:Genome; D007438:Introns; D008297:Male; D008957:Models, Genetic; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D011544:Pseudogenes; D014178:Translocation, Genetic; D014960:X Chromosome / Q000235:genetics / Q000502:physiology; D014998:Y Chromosome / Q000235:genetics* / Q000502:physiology*
D021901:DNA, Intergenic