The occurrence of Guillain-Barre syndrome within families.
This report describes 12 Dutch families of which at least two members have had Guillain-Barre syndrome (GBS). The authors observed an earlier onset of GBS in successive generations. The occurrence of GBS within families suggests a role for genetic factors in the pathogenesis of GBS.
Geleijns
K
K
Department of Neurology, Room Ee 2230, Erasmus Medical Center, PO Box 1738, 3000 DR Rotterdam, The Netherlands. c.geleijns@erasmusmc.nl
Brouwer
B A
BA
Jacobs
B C
BC
Houwing-Duistermaat
J J
JJ
van Duijn
C M
CM
van Doorn
P A
PA
D000328:Adult; D017668:Age of Onset; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D020022:Genetic Predisposition to Disease; D020275:Guillain-Barre Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D010375:Pedigree