title: Hypertrophic pachymeningitis as an initial and cardinal manifestation of microscopic polyangiitis.
abstract: The authors describe a 68-year-old man who developed hypertrophic pachymeningitis as an initial and cardinal manifestation of microscopic polyangiitis. The patient had a high titer of antineutrophil cytoplasmic antibody for myeloperoxidase. Biopsies revealed necrotizing glomerulonephritis in the kidney, small vessel vasculitis in the sural nerve, and infiltration of plasma cells and eosinophils in the thickened dura mater.
authors.affiliation: Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, 13-1, Takara-machi, Kanazawa, Ishikawa 920-8640, Japan. furukawa@med.kanazawa-u.ac.jp
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Furukawa
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Matsumoto
authors.forename: Masahito
authors.initials: M
authors.lastname: Yamada
mesh_terms: D000368:Aged; D004388:Dura Mater / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008581:Meningitis / Q000175:diagnosis / Q000473:pathology*; D008833:Microcirculation; D013497:Sural Nerve / Q000473:pathology; D014657:Vasculitis / Q000175:diagnosis / Q000473:pathology*