title: Adjuvant high dose rate brachytherapy (Ir-192) in the management of keloids which have recurred after surgical excision and external radiation.
abstract: We describe our experience with adjuvant high dose rate brachytherapy (Ir-192) (HDRB) in patients, who failed surgery and post-operative external radiation therapy. The salvage treatment consisted of excision of the keloid and wound closure followed by HDRB (15 Gy in three fractions given on three consecutive business days beginning the day of surgery). At the time of last follow up, 88% (15/17) of the keloids were without any evidence of recurrence.
authors.affiliation: Department of Radiation Oncology, Montefiore Medical Center, Bronx, NY 10467, USA.
authors.forename: Madhur K
authors.initials: MK
authors.lastname: Garg
authors.forename: Paul
authors.initials: P
authors.lastname: Weiss
authors.forename: Anand K
authors.initials: AK
authors.lastname: Sharma
authors.forename: Giridhar R
authors.initials: GR
authors.lastname: Gorla
authors.forename: Wainwright
authors.initials: W
authors.lastname: Jaggernauth
authors.forename: Ravindra
authors.initials: R
authors.lastname: Yaparpalvi
authors.forename: John
authors.initials: J
authors.lastname: Delrowe
authors.forename: Jonathan J
authors.initials: JJ
authors.lastname: Beitler
mesh_terms: D000293:Adolescent; D000328:Adult; D001918:Brachytherapy; D015331:Cohort Studies; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007627:Keloid / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011879:Radiotherapy Dosage; D018714:Radiotherapy, Adjuvant; D012008:Recurrence; D018570:Risk Assessment; D012720:Severity of Illness Index; D013514:Surgical Procedures, Operative / Q000379:methods; D017211:Treatment Failure; D016896:Treatment Outcome