title: Bubble generation in a twisted and bent DNA-like model.
abstract: The DNA molecule is modeled by a parabola embedded chain with long-range interactions between twisted base pair dipoles. A mechanism for bubble generation is presented and investigated in two different configurations. Using random normally distributed initial conditions to simulate thermal fluctuations, a relationship between bubble generation, twist and curvature is established. An analytical approach supports the numerical results.
authors.affiliation: Informatics and Mathematical Modelling and Department of Mathematics, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark. p.v.larsen@mat.dtu.dk
authors.forename: P V
authors.initials: PV
authors.lastname: Larsen
authors.forename: P L
authors.initials: PL
authors.lastname: Christiansen
authors.forename: O
authors.initials: O
authors.lastname: Bang
authors.forename: J F R
authors.initials: JF
authors.lastname: Archilla
authors.forename: Yu B
authors.initials: YB
authors.lastname: Gaididei