title: High resolution electrospray and electrospray tandem mass spectra of rotenone and its isoxazoline cycloadducts.
abstract: An evaluation of the gas-phase ion chemistry of rotenone (1) by electrospray ionisation (ESI) mass spectrometry (MS) and tandem mass spectrometry (MS2) is presented, aiming at providing tools for its determination in natural and biological matrices. The behaviour of its cycloadducts with benzonitrile-N-oxide (2) and 2,4,6-trimethylbenzonitrile-N-oxide (3) was also evaluated and the MS data thus obtained have provided evidence into the mechanism of formation of the key product ion at m/z 192 which can be considered a marker in the MS and MS2 spectra of rotenone and its derivatives.
authors.affiliation: Dipartimento di Chimica Organica e Biologica, Università, Vill. S. Agata, I-98166 Messina, Italy.
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Cordaro
authors.forename: Leonardo
authors.initials: L
authors.lastname: Di Donna
authors.forename: Giovanni
authors.initials: G
authors.lastname: Grassi
authors.forename: Loredana
authors.initials: L
authors.lastname: Maiuolo
authors.forename: Fabio
authors.initials: F
authors.lastname: Mazzotti
authors.forename: Enzo
authors.initials: E
authors.lastname: Perri
authors.forename: Giovanni
authors.initials: G
authors.lastname: Sindona
authors.forename: Antonio
authors.initials: A
authors.lastname: Tagarelli
mesh_terms: D003500:Cyclization; D006571:Heterocyclic Compounds; D007306:Insecticides / Q000737:chemistry*; D007555:Isoxazoles / Q000737:chemistry*; D015394:Molecular Structure; D012402:Rotenone / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000295:instrumentation* / Q000379:methods*
chemical_list: D006571:Heterocyclic Compounds; D007306:Insecticides; D007555:Isoxazoles; D012402:Rotenone