[The QOL of the patient with advanced pancreatic carcinoma was changed for the better with combination therapy consisting of arterial chemotherapy and injection of interferon].
The prognosis of advanced pancreatic carcinoma with multiple liver metastases is extremely poor. The current methods of treating pancreatic carcinoma are far from satisfactory. The results of systemic and regional chemotherapies for pancreatic carcinoma are disappointing. The patient was a 68-year-old male with advanced pancreatic carcinoma. After an operation, he received a combination therapy consisting of arterial infusion (gemcitabine hydrochloride, GEM, 600 mg) and muscle injection of interferon (IFN, 300x10(4) U). A decrease in metastatic tumor of the liver was observed. In this report, we describe the case of a patient whose effective results were achieved by using a new combination of GEM and IFN.
Funahashi
Hitoshi
H
Dept. of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences.
Sawai
Hirozumi
H
Okada
Yuji
Y
Sakamoto
Masaki
M
Takahashi
Hiroki
H
Matsuo
Youichi
Y
Wakasugi
Takehiro
T
Yamamoto
Minoru
M
Takeyama
Hiromitsu
H
Manabe
Tadao
T
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D006801:Humans; D007261:Infusions, Intra-Arterial; D007372:Interferons / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000556:secondary; D008297:Male; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000628:therapy*; D011788:Quality of Life; D000093542:Gemcitabine
D003841:Deoxycytidine; D007372:Interferons; D000093542:Gemcitabine