title: Peripancreatic Castleman disease.
abstract: BACKGROUND
  Castleman disease or giant lymph node hyperplasia is a rare disorder of the lymphoid tissue, usually occurring in the mediastinum. We report a case of localized peripancreatic plasma cell type Castleman disease, which is an unusual site.
  
  
  METHODS
  A 45-year-old woman with a history of mild epigastric pain radiating to the back for the previous year was admitted and her physical examination was normal. A raised erythrocyte sedimentation rate, C-reactive protein and hypergammaglobulinemia were found. Abdominal ultrasonography and magnetic resonance imaging demonstrated a homogeneously hypoechoic solid mass having a smooth-surface, 6 cm in diameter, located between the head of the pancreas, the lower margin of the antrum and the left lobe of the liver. The mass was totally excised surgically with repair of the pancreas capsule. Histopathological examination of the tumor showed plasma-cell type Castleman disease.
  
  
  CONCLUSIONS
  Clinicians should be aware that Castleman disease may involve peripancreatic tissue which leads to difficulties in arriving at a differential diagnosis. Surgical excision is both a diagnostic and a curative method for management of the disease.
authors.affiliation: Department of 2nd Surgery, SSK Izmir Training Hospital, Izmir, Turkey. naziferkan2002@hotmail.com
authors.forename: Nazif
authors.initials: N
authors.lastname: Erkan
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yildirim
authors.forename: Elif
authors.initials: E
authors.lastname: Selek
authors.forename: Sehnaz
authors.initials: S
authors.lastname: Sayhan
mesh_terms: D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000032:analysis; D005871:Castleman Disease / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D004386:Duodenum / Q000473:pathology; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010179:Pancreas / Q000473:pathology
chemical_list: D002097:C-Reactive Protein