title: Testicular seminoma 16 years after treatment for CNS germinoma.
abstract: Most patients with intracranial germinomas will be cured and become long-term survivors. Physicians caring for these patients should recognize that these patients may be at risk for disease-related and/or treatment-related late sequelae. We report the case of a 27-year-old man who developed testicular seminoma 16 years after treatment for intracranial germinoma. Like their testicular cancer counterparts, long-term survivors of intracranial germinomas may have a susceptibility to develop a subsequent germ cell tumor. These patients require lifelong medical follow-up and should be encouraged to perform testicular self-examination at the appropriate age.
authors.affiliation: Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia 19104, USA. maity@xrt.upenn.edu
authors.forename: Amit
authors.initials: A
authors.lastname: Maity
authors.forename: Hui-Kuo G
authors.initials: HK
authors.lastname: Shu
authors.forename: Alexander R
authors.initials: AR
authors.lastname: Judkins
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Fisher
authors.forename: Lisa E A
authors.initials: LE
authors.lastname: Dwyer-Joyce
authors.forename: David J
authors.initials: DJ
authors.lastname: Vaughn
mesh_terms: D000328:Adult; D000359:Aftercare; D001932:Brain Neoplasms / Q000473:pathology* / Q000628:therapy; D016371:Cranial Irradiation; D003399:Craniotomy; D018237:Germinoma / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary; D018239:Seminoma / Q000473:pathology* / Q000601:surgery; D013736:Testicular Neoplasms / Q000473:pathology* / Q000628:therapy