title: Synthesis of enantiopure imidazolines through a Ritter reaction of 2-(1-aminoalkyl)aziridines with nitriles.
abstract: The Ritter reaction of enantiopure 2-(1-aminoalkyl)aziridines 1 with different nitriles afford enantiopure tetrasubstituted imidazolines 2. The opening of the aziridine ring takes place with total regio- and stereoselectivity. A mechanism to explain the described addition reaction is proposed. [reaction: see text]
authors.affiliation: Departamento de Química Orgánica e Inorgánica y Departamento de Química Física y Analítica, Facultad de Química Universidad de Oviedo, Julián Clavería 8, 33071 Oviedo, Spain. jmcg@fq.uniovi.es
authors.forename: José M
authors.initials: JM
authors.lastname: Concellón
authors.forename: Estela
authors.initials: E
authors.lastname: Riego
authors.forename: José Ramón
authors.initials: JR
authors.lastname: Suárez
authors.forename: Santiago
authors.initials: S
authors.lastname: García-Granda
authors.forename: M Rosario
authors.initials: MR
authors.lastname: Díaz