title: [Protective effect of ganfukang capsule on hepatocytes in rats with experimental hepatic fibrosis].
abstract: OBJECTIVE
  To observe the protective effect of ganfukang capsule on hepatocytes of rats with experimental hepatic fibrosis rat.
  
  
  METHODS
  SD rat model of liver fibrosis was induced by CCl4. The effect of ganfukang capsule on liver function, histological change and ultrastructural were examined.
  
  
  RESULTS
  Liver function, histological change and ultrastructural were significantly improved. The degree of steatosis was significantly decreased.
  
  
  CONCLUSIONS
  Ganfukang capsule might protect hepatocytes, mitochondria from the injury induced by CCl4 and improve liver function.
authors.affiliation: The First Affiliated Hospital of Dalian Medical University.
authors.forename: Ying
authors.initials: Y
authors.lastname: Che
authors.forename: Tingting
authors.initials: T
authors.lastname: Xu
authors.forename: Miaona
authors.initials: M
authors.lastname: Jiang
authors.forename: Yujie
authors.initials: Y
authors.lastname: Jia
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D002214:Capsules; D002252:Carbon Tetrachloride Poisoning; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D022781:Hepatocytes / Q000187:drug effects* / Q000473:pathology; D008106:Liver Cirrhosis, Experimental / Q000139:chemically induced / Q000378:metabolism / Q000473:pathology*; D008111:Liver Function Tests; D020011:Protective Agents / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D002214:Capsules; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D020011:Protective Agents; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase