Potential role of the ventilation and perfusion (V/Q) lung scan in the diagnosis of acute chest syndrome in adults with sickle cell disease.
The current criteria for diagnosing ACS are chest pain and presence of a new infiltrate on the chest radiograph (CXR). This study was designed to evaluate the role of ventilation and perfusion (V/Q) scan to assist in the early diagnosis of ACS. An abnormal V/Q scan was associated with a diagnosis of ACS that reached a statistical significance (P < 0.038). The sensitivity and specificity were found to be 60% and 100%, respectively. We conclude that V/Q scan may play a role in the early diagnosis of ACS.
Kaur
Navleen
N
Department of Medicine, Finch University of Health Sciences/The Chicago Medical School at Mount Sinai Hospital Medical Center, Chicago, Illinois 60608, USA.
Motwani
Bharat
B
Sivasubramaniam
Devaki
D
Feldman
Lori
L
Allen
Sandra
S
Ferguson
Richard
R
Shiomoto
Gail
G
Ansell
David
D
Westerman
Maxwell
M
Feldman
Lawrence
L
D000328:Adult; D000755:Anemia, Sickle Cell / Q000097:blood / Q000150:complications*; D001772:Blood Cell Count; D002637:Chest Pain / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014692:Ventilation-Perfusion Ratio
D006454:Hemoglobins