Involvement of thalamic paraventricular nucleus in the anticipatory reaction under food restriction in the rat.
To investigate which brain regions are involved in the anticipatory activity in rats restricted feeding for 2 hr, we examined c-Fos expression before and after feeding. Only the thalamic paraventricular nucleus (tPVN) showed c-Fos expression before feeding than after feeding. After the anticipatory locomotor activity rhythm was established, lesioning the tPVN attenuated this rhythm, but not the light-dark entrained rhythm. The anticipatory increase of blood corticosterone levels was not established in long-term tPVN-lesioned rats. These results suggest that the tPVN is involved in the expression of anticipatory reactions under a food-restricted regimen.
Nakahara
Keiko
K
Department of Veterinary Physiology, Faculty of Agriculture, University of Miyazaki, Japan.
Fukui
Kento
K
Murakami
Noboru
N
D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology*; D003345:Corticosterone / Q000097:blood; D005247:Feeding Behavior / Q000502:physiology*; D005508:Food Deprivation / Q000502:physiology*; D008124:Locomotion / Q000502:physiology; D020644:Midline Thalamic Nuclei / Q000378:metabolism / Q000502:physiology*; D016760:Proto-Oncogene Proteins c-fos / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar
D016760:Proto-Oncogene Proteins c-fos; D003345:Corticosterone