title: Rhodium-catalyzed novel trifluoromethylation at the alpha-position of alpha,beta-unsaturated ketones.
abstract: Treatment of alpha,beta-unsaturated ketones with CF(3)I in the presence of Et(2)Zn and RhCl(PPh(3))(3) gave novel alpha-trifluoromethylation products in good yields. Hydrogen transfer from the ethyl group on the rhodium complex to the beta-position of the enone seems to play an important role in this reaction.
authors.affiliation: Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka 573-0101, Japan.
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Sato
authors.forename: Masaaki
authors.initials: M
authors.lastname: Omote
authors.forename: Akira
authors.initials: A
authors.lastname: Ando
authors.forename: Itsumaro
authors.initials: I
authors.lastname: Kumadaki