title: False-positive Aspergillus galactomannan enzyme-linked immunosorbent assay results in vivo during amoxicillin-clavulanic acid treatment.
abstract: Positive Platelia Aspergillus test results were observed in consecutive serum samples from an immunocompromised host during amoxicillin-clavulanic acid treatment, and a correlation between plasmatic amoxicillin concentration and galactomannan optical density index was observed. Amoxicillin-clavulanic acid vials tested positive for galactomannan but were negative for Aspergillus DNA.
authors.affiliation: Department of Hematology, Santa Croce Hospital, Via Michele Coppino 26, 12100 Cuneo, Italy. daealemattei@tin.it
authors.forename: Daniele
authors.initials: D
authors.lastname: Mattei
authors.forename: Davide
authors.initials: D
authors.lastname: Rapezzi
authors.forename: Nicola
authors.initials: N
authors.lastname: Mordini
authors.forename: Federica
authors.initials: F
authors.lastname: Cuda
authors.forename: Cristiana
authors.initials: C
authors.lastname: Lo Nigro
authors.forename: Maura
authors.initials: M
authors.lastname: Musso
authors.forename: Aldo
authors.initials: A
authors.lastname: Arnelli
authors.forename: Sebastiano
authors.initials: S
authors.lastname: Cagnassi
authors.forename: Andrea
authors.initials: A
authors.lastname: Gallamini
mesh_terms: D019980:Amoxicillin-Potassium Clavulanate Combination / Q000627:therapeutic use*; D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy*; D001230:Aspergillus / Q000302:isolation & purification; D004797:Enzyme-Linked Immunosorbent Assay; D005189:False Positive Reactions; D005260:Female; D005690:Galactose / Q000031:analogs & derivatives; D006801:Humans; D016867:Immunocompromised Host; D008351:Mannans / Q000032:analysis*; D008875:Middle Aged; D011933:Reagent Kits, Diagnostic
chemical_list: D008351:Mannans; D011933:Reagent Kits, Diagnostic; C012990:galactomannan; D019980:Amoxicillin-Potassium Clavulanate Combination; D005690:Galactose