Consequences of increased neuromotor noise for reaching movements in persons with stroke.
Understanding stroke-induced changes to the motor control of the more affected arm of people with stroke may lead to more effective rehabilitation interventions that improve function. Reaching movements of the more affected arm in persons with stroke are slow, segmented, and indirect. Such changes may be related to a reduced capacity to transmit motor commands in the presence of neuromotor noise. In tasks requiring both speed and accuracy, transmission capacity can be characterized by the linear relationship between movement time and task difficulty (Fitts' law). This study quantified Fitts' slope and intercept coefficients in stroke during reaching tasks and their relationship to kinematic measures of path accuracy (directness), trajectory corrections (segmentation), and planning strategy (skewness). We compared Fitts' slope and intercept and kinematics among the more and the less affected arm of 20 persons with stroke and the nondominant arm of ten healthy persons. Slope and intercept were significantly increased in the more affected arm of the group with stroke and related to clinical measurements of motor impairment and tone. For both the more and the less affected arm of the group with stroke, increased slopes and intercepts were correlated to more indirect, segmented, and positively skewed movement. Our findings suggest that stroke results in greater neuromotor noise, which has consequences for both motor execution and planning. Individuals with stroke demonstrate substantially more deviation from straight-line paths than do controls, despite using more conservative strategies (i.e., leftward shift of velocity profile) and extensive feedback control (i.e., segmentation).
McCrea
Patrick H
PH
Department of Mechanical Engineering, University of BC, Vancouver, Canada.
Eng
Janice J
JJ
D000368:Aged; D001132:Arm / Q000294:innervation / Q000503:physiopathology*; D001696:Biomechanical Phenomena; D001921:Brain / Q000503:physiopathology*; D004525:Efferent Pathways / Q000502:physiology; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008959:Models, Neurological; D009068:Movement / Q000502:physiology*; D009069:Movement Disorders / Q000209:etiology / Q000503:physiopathology*; D011597:Psychomotor Performance / Q000502:physiology; D020521:Stroke / Q000503:physiopathology*; D009435:Synaptic Transmission / Q000502:physiology