title: [Altered parameters of respiration mechanics as compared with clinical and X-ray changes in new cases of pulmonary tuberculosis].
abstract: This study was undertaken to explore changes in the mechanics of respiration in new cases of pulmonary tuberculosis during 3-4-month chemotherapy as compared to the course of a tuberculous process, which was based on the times of bacterial isolation cession and cavernous closures. A hundred and thirty-four patients (95 males and 39 females) with different forms of tuberculosis were followed up. The study of external respiratory function involved spirometry, determination of forced expiratory flow-volume, body plethysmography, examination of the mechanics of the lung by esophageal probing. During chemotherapy, bronchial patiency, the elastic constituent of pulmonary impedance, total bronchial resistance, and respiratory performance were ascertained to vary independently of one another. The authors have identified the factors that most greatly influence these changes: baseline bronchial obstruction on the one hand and the form of tuberculosis and the severity of a destructive process in the lung on the other one. A significant association of the time course of changes was found in the mechanics of the lung and in a tuberculous process, which was based on the times of bacterial isolation cession and cavernous closures.
authors.forename: M F
authors.initials: MF
authors.lastname: Iaushev
authors.forename: L V
authors.initials: LV
authors.lastname: Khabibullina
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D011859:Radiography; D012137:Respiratory System / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D012720:Severity of Illness Index; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging* / Q000503:physiopathology*