title: Comparison of measurement of cross-sectional coronary atherosclerotic plaque and vessel areas by 16-slice multidetector computed tomography versus intravascular ultrasound.
abstract: In 26 patients, 16-slice multidetector computed tomography (MDCT) with 0.75-mm collimation and intravascular ultrasound (IVUS) of 1 coronary artery were performed. At 100 sites within the coronary arteries, the measurement of cross-sectional luminal area and, if detectable, the cross-sectional area of atherosclerotic plaque was performed independently with IVUS and MDCT. The mean luminal area (r = 0.92), measured at 100 sites, and plaque area (r = 0.55), measured at 65 sites, were significantly correlated (p <0.001) between MDCT and IVUS. The mean luminal area and mean plaque area were slightly but significantly overestimated with MDCT. MDCT permits the noninvasive measurement of coronary cross-sectional luminal and plaque areas with moderate accuracy.
authors.affiliation: Division of Cardiology, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA.
authors.forename: Fabian
authors.initials: F
authors.lastname: Moselewski
authors.forename: Dieter
authors.initials: D
authors.lastname: Ropers
authors.forename: Karsten
authors.initials: K
authors.lastname: Pohle
authors.forename: Udo
authors.initials: U
authors.lastname: Hoffmann
authors.forename: Maros
authors.initials: M
authors.lastname: Ferencik
authors.forename: Ray C
authors.initials: RC
authors.lastname: Chan
authors.forename: Ricardo C
authors.initials: RC
authors.lastname: Cury
authors.forename: Suhny
authors.initials: S
authors.lastname: Abbara
authors.forename: Ik-Kyung
authors.initials: IK
authors.lastname: Jang
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Brady
authors.forename: Werner G
authors.initials: WG
authors.lastname: Daniel
authors.forename: Stephan
authors.initials: S
authors.lastname: Achenbach
mesh_terms: D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D018084:Ultrasonography, Interventional