Cross-protection study of the nine serovars of Haemophilus paragallinarum in the Kume haemagglutinin scheme.
The cross-protection and haemagglutination-inhibition antibodies present in chickens vaccinated with one of the nine currently recognized Kume haemagglutinin serovars of Haemophilus paragallinarum were investigated. The results confirmed the widely accepted dogma that serogroups A, B, and C represent three distinct immunovars. Within Kume serogroup A, there was generally good cross-protection among all four serovars. However, within Kume serogroup C, there was evidence of a reduced level of cross-protection between some of the four serovars. The haemagglutination-inhibition antibody levels generally showed the same trend as with the cross-protection results. This study suggests that some apparent field failures of infectious coryza vaccines may be due to a lack of cross-protection between the vaccine strains and the field strains. Our results will help guide the selection of strains for inclusion in infectious coryza vaccines.
Soriano
Edgardo V
EV
Centro de Investigación y Estudios Avanzados en Salud Animal, Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca 50000, México. soriano@uaemex.mx
Garduño
Manuel Longinos
ML
Téllez
Guillermo
G
Rosas
Pomposo Fernández
PF
Suárez-Güemes
Francisco
F
Blackall
Patrick J
PJ
D000818:Animals; D002645:Chickens / Q000382:microbiology*; D003139:Common Cold / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control / Q000662:veterinary*; D003429:Cross Reactions / Q000276:immunology*; D006192:Haemophilus Infections / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary*; D044134:Haemophilus paragallinarum / Q000145:classification / Q000276:immunology*; D006386:Hemagglutination Tests / Q000662:veterinary; D011201:Poultry Diseases / Q000276:immunology* / Q000382:microbiology; D012703:Serotyping / Q000379:methods / Q000662:veterinary; D013045:Species Specificity; D014611:Vaccination / Q000662:veterinary*