Convenience of serum for visceral leishmaniasis diagnosis by PCR.
In this retrospective study, the usefulness of a PCR performed on serum for primary diagnosis and monitoring of Mediterranean visceral leishmaniasis (MVL) was assessed. In the case of primary diagnosis of MVL, the serum PCR showed a sensitivity of 97% and a specificity of 95%, with positive and negative predictive values of 94 and 97%, respectively.
Fissore
Cristel
C
Equipe de Recherche sur les Leishmanioses, Université de Nice-Sophia-Antipolis, Nice, France. fissore.c@chu-nice.fr
Delaunay
Pascal
P
Ferrua
Bernard
B
Rosenthal
Eric
E
Del Giudice
Pascal
P
Aufeuvre
Jean-Pierre
JP
Le Fichoux
Yves
Y
Marty
Pierre
P
D000328:Adult; D000818:Animals; D002648:Child; D016054:DNA, Protozoan / Q000032:analysis / Q000097:blood*; D006801:Humans; D018314:Leishmania infantum / Q000235:genetics / Q000302:isolation & purification*; D007898:Leishmaniasis, Visceral / Q000175:diagnosis*; D016133:Polymerase Chain Reaction / Q000379:methods*; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity
D016054:DNA, Protozoan