Stochastic Liouville equation simulation of multidimensional vibrational line shapes of trialanine.
The line shapes detected in coherent femtosecond vibrational spectroscopies contain direct signatures of peptide conformational fluctuations through their effect on vibrational frequencies and intermode couplings. These effects are simulated in trialanine using a Green's function solution of a stochastic Liouville equation constructed for four collective bath coordinates (two Ramachandran angles affecting the mode couplings and two diagonal energies). We find that fluctuations of the Ramachandran angles which hardly affect the linear absorption can be effectively probed by two-dimensional spectra. The signal generated at k(1)+k(2)-k(3) is particularly sensitive to such fluctuations.
Jansen
Thomas la Cour
Tl
Department of Chemistry, University of California, Irvine, CA 92697-2025, USA.
Zhuang
Wei
W
Mukamel
Shaul
S
D000409:Alanine / Q000737:chemistry*; D003198:Computer Simulation; D008956:Models, Chemical; D008958:Models, Molecular; D013057:Spectrum Analysis / Q000379:methods*; D014732:Vibration
D000409:Alanine