Porcine circovirus as a possible cause of postweaning wasting in pigs in Switzerland.
Postweaning wasting is a major worldwide problem in pig production, particularly with respect to the disease termed postweaning multisystemic wasting syndrome (PMWS). In addition to wasting, PMWS symptoms include respiratory distress, diarrhoea, pallor and occasional cases of jaundice. The causative agent is porcine circovirus type 2 (PCV-2). The objective of the present study was to determine the significance of PMWS and similar conditions in Switzerland. A total of 72 weaned piglets from 26 farms showing wasting were examined for the presence of PCV-2 by immunohistochemical and histological analysis and 57 piglets from 21 farms were examined serologically. Possible causes for wasting other than PCV-2 were investigated by macroscopic, histological and bacteriological methods. PCV-2 antigen was identified immunohistochemically in the lymphatic organs in 11 of these 72 piglets. However, only 4 animals showed histological changes typical of PMWS. PCV-2 antibodies were found in 70% of the piglets. Piglets with wasting syndrome not associated with PCV-2 infection suffered from conditions including porcine proliferative enteropathy, gastric ulcers, polyserositis and polyarthritis. The most frequent condition was chronic enteritis not associated to circovirus infection. The results from the serological analyses indicate a wide distribution of PCV-2 in the Swiss pig population. However, confirmed cases of PMWS were rare in the investigated piglets.
Staebler
S
S
Institute of Veterinary Pathology, University of Zurich, Switzerland.
Buergi
E
E
Litzenberger
B
B
McCullough
K
K
McNair
I
I
McNeilly
F
F
Pospischil
A
A
Sydler
T
T
D000818:Animals; D000831:Animals, Newborn; D000914:Antibodies, Viral / Q000097:blood; D000956:Antigens, Viral / Q000032:analysis; D018173:Circoviridae Infections / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary*; D017925:Circovirus / Q000276:immunology / Q000302:isolation & purification*; D005260:Female; D007150:Immunohistochemistry / Q000379:methods / Q000662:veterinary; D008297:Male; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology* / Q000473:pathology / Q000821:virology; D013557:Switzerland; D019282:Wasting Syndrome / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D014886:Weaning
D000914:Antibodies, Viral; D000956:Antigens, Viral