Hypertrophic pachymeningitis as an initial and cardinal manifestation of microscopic polyangiitis.
The authors describe a 68-year-old man who developed hypertrophic pachymeningitis as an initial and cardinal manifestation of microscopic polyangiitis. The patient had a high titer of antineutrophil cytoplasmic antibody for myeloperoxidase. Biopsies revealed necrotizing glomerulonephritis in the kidney, small vessel vasculitis in the sural nerve, and infiltration of plasma cells and eosinophils in the thickened dura mater.
Furukawa
Yutaka
Y
Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, 13-1, Takara-machi, Kanazawa, Ishikawa 920-8640, Japan. furukawa@med.kanazawa-u.ac.jp
Matsumoto
Yasuko
Y
Yamada
Masahito
M
D000368:Aged; D004388:Dura Mater / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008581:Meningitis / Q000175:diagnosis / Q000473:pathology*; D008833:Microcirculation; D013497:Sural Nerve / Q000473:pathology; D014657:Vasculitis / Q000175:diagnosis / Q000473:pathology*