title: Potential role of the ventilation and perfusion (V/Q) lung scan in the diagnosis of acute chest syndrome in adults with sickle cell disease.
abstract: The current criteria for diagnosing ACS are chest pain and presence of a new infiltrate on the chest radiograph (CXR). This study was designed to evaluate the role of ventilation and perfusion (V/Q) scan to assist in the early diagnosis of ACS. An abnormal V/Q scan was associated with a diagnosis of ACS that reached a statistical significance (P < 0.038). The sensitivity and specificity were found to be 60% and 100%, respectively. We conclude that V/Q scan may play a role in the early diagnosis of ACS.
authors.affiliation: Department of Medicine, Finch University of Health Sciences/The Chicago Medical School at Mount Sinai Hospital Medical Center, Chicago, Illinois 60608, USA.
authors.forename: Navleen
authors.initials: N
authors.lastname: Kaur
authors.forename: Bharat
authors.initials: B
authors.lastname: Motwani
authors.forename: Devaki
authors.initials: D
authors.lastname: Sivasubramaniam
authors.forename: Lori
authors.initials: L
authors.lastname: Feldman
authors.forename: Sandra
authors.initials: S
authors.lastname: Allen
authors.forename: Richard
authors.initials: R
authors.lastname: Ferguson
authors.forename: Gail
authors.initials: G
authors.lastname: Shiomoto
authors.forename: David
authors.initials: D
authors.lastname: Ansell
authors.forename: Maxwell
authors.initials: M
authors.lastname: Westerman
authors.forename: Lawrence
authors.initials: L
authors.lastname: Feldman
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000097:blood / Q000150:complications*; D001772:Blood Cell Count; D002637:Chest Pain / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014692:Ventilation-Perfusion Ratio
chemical_list: D006454:Hemoglobins