title: Hormonal monitoring of the first trimester of pregnancy.
abstract: The hormonal changes and maternal adaptations of human pregnancy are among the most remarkable phenomena in nature. Endocrinologic parameters in the early gestation period have been used to predict abnormal pregnancies and to identify fetuses that have chromosomal aberrations. This article focuses on the changes in hormones that are secreted by the maternal-fetal-placental unit that are unique for the first trimester of pregnancy and their impact on clinical outcome.
authors.affiliation: Cerrahpasa Medical Faculty, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, Istanbul University, Cerrahpasa PTT PK 31, 34301 Istanbul, Turkey. eoral@superonline.com
authors.forename: Engin
authors.initials: E
authors.lastname: Oral
authors.forename: Mehmet R
authors.initials: MR
authors.lastname: Genç
mesh_terms: D002272:Carcinoembryonic Antigen / Q000378:metabolism; D016207:Cytokines / Q000378:metabolism; D005260:Female; D055436:Growth Differentiation Factor 15; D006728:Hormones / Q000378:metabolism*; D006801:Humans; D018970:Insulin-Like Growth Factor Binding Protein 1 / Q000378:metabolism; D008263:Macrophage Migration-Inhibitory Factors / Q000378:metabolism; D011247:Pregnancy / Q000378:metabolism*; D011261:Pregnancy Trimester, First / Q000502:physiology*; D011266:Pregnancy-Associated Plasma Protein-A / Q000378:metabolism
chemical_list: D002272:Carcinoembryonic Antigen; D016207:Cytokines; C526140:GDF15 protein, human; D055436:Growth Differentiation Factor 15; D006728:Hormones; D018970:Insulin-Like Growth Factor Binding Protein 1; D008263:Macrophage Migration-Inhibitory Factors; D011266:Pregnancy-Associated Plasma Protein-A