title: [The inhibitive effects of the ethanol extract from Radix et Rhizoma Rhei on the secretion of HBsAg and HBeAg].
abstract: OBJECTIVE
  To study the anti-HBV effects of the ethanol extract from Radix et Rhizoma Rhei.
  
  
  METHODS
  The influence of the ethanol extract from Radix et Rhizoma Rhei on the secretion of HBeAg and HBsAg was observed through the culture of the 2.2.15 cell with the ethanol extract.
  
  
  RESULTS
  11 days after the ethanol extract's action on the 2.2.15 cell, its 50% concentration dose (CD50) is 39.69 g/L; inhibiting dose (ID50) to HBsAg and HBeAg are 3.29 g/L and 2.34 g/L respectively, and TI 12.06 and 16.96 respectively.
  
  
  CONCLUSIONS
  The ethanol extract from Radix et Rhizoma Rhei can markedly inhibit the secretion of HBsAg and HBeAg in 2.2.25 cell lines.
authors.affiliation: Institute of Tropical Medicine, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405.
authors.forename: Ni
authors.initials: N
authors.lastname: Liu
authors.forename: Bianxian
authors.initials: B
authors.lastname: Zhu
authors.forename: Zhengchang
authors.initials: Z
authors.lastname: Huang
authors.forename: Yutong
authors.initials: Y
authors.lastname: Zhu
authors.forename: Qiaoyan
authors.initials: Q
authors.lastname: Chen
authors.forename: Xingbo
authors.initials: X
authors.lastname: Guo
authors.forename: Guoqiao
authors.initials: G
authors.lastname: Li
mesh_terms: D000998:Antiviral Agents / Q000494:pharmacology*; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D004642:Emodin / Q000494:pharmacology; D000431:Ethanol; D006514:Hepatitis B Surface Antigens / Q000096:biosynthesis*; D006513:Hepatitis B e Antigens / Q000096:biosynthesis*; D006515:Hepatitis B virus / Q000187:drug effects / Q000276:immunology; D010946:Plants, Medicinal / Q000737:chemistry*; D012250:Rheum / Q000737:chemistry; D027343:Rhizome / Q000737:chemistry
chemical_list: D000998:Antiviral Agents; D004365:Drugs, Chinese Herbal; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens; D000431:Ethanol; D004642:Emodin