Di- and tri-alkylphosphine adducts of S-donor palladacycles as catalysts in the Suzuki coupling of aryl chlorides.
The reaction of tricyclohexylphosphine with the S-based palladacycle [(Pd(mu-OAc)(kappa2-S,C-C(6)H(4)CH(2)SMe))(2)] gives several products, regardless of stoichiometry, one of which, [Pd(kappa1-OAc)(eta1-C(6)H(4)CH(2)SMe)(PCy3)2], has been characterised crystallographically. Despite this, catalysts formed in situ from di- and tri-alkylphosphines and [(Pd(mu-OAc)(kappa2-S,C-C(6)H(4)CH(2)SMe))2] show excellent activity in the Suzuki coupling of a range of deactivated, non-activated and activated aryl chloride substrates.
Bedford
Robin B
RB
Department of Chemistry, University of Exeter, Exeter EX4 4QD, UK. r.bedford@ex.ac.uk
Cazin
Catherine S J
CS
Hursthouse
Michael B
MB
Light
Mark E
ME
Scordia
Véronique J M
VJ