Nitrile oxide cycloadditions in supercritical carbon dioxide.
The regioselectivity of dipolar cycloadditions of mesitonitrile oxide to various dipolarophiles in supercritical carbon dioxide can be tuned by changes in density, the magnesium bromide-mediated cycloaddition to pent-1-en-3-ol proceeding with higher stereoselectivity than in most conventional solvents.
Lee
Connie K Y
CK
Melville Laboratory for Polymer Synthesis, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK CB2 1EW. abh1@cam.ac.uk
Holmes
Andrew B
AB
Al-Duri
Bushra
B
Leeke
Gary A
GA
Santos
Regina C D
RC
Seville
Jonathan P K
JP