Aspirin treatment for neonatal infectious endocarditis.
We describe a term female neonate with Serratia marcescens endocarditis. Despite adequate antibiotic therapy for 8 days, the bacteremia persisted and there was an increase in vegetation size. Treatment with aspirin was initiated, with resolution of the bacteremia and a gradual decrease in vegetation size. We conclude that in neonatal endocarditis, aspirin may be beneficial additional treatment.
Adler
A
A
Department of Neonatology, Meir Medical Center, Kfar-Saba, Israel.
Litmanovitz
I
I
Bauer
S
S
Dolfin
T
T
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004697:Endocarditis, Bacterial / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D000077731:Meropenem; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D016868:Serratia Infections / Q000188:drug therapy*; D012706:Serratia marcescens; D013845:Thienamycins / Q000627:therapeutic use; D014640:Vancomycin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D010975:Platelet Aggregation Inhibitors; D013845:Thienamycins; D014640:Vancomycin; D000077731:Meropenem; D001241:Aspirin