Dyslipidemia in patients with angiographically confirmed coronary artery disease--an opportunity for improvement.
BACKGROUND
There are few data about lipid profiles in unselected patients with angiographically confirmed coronary artery disease (CAD).


OBJECTIVE
The study was undertaken to investigate the demographics, clinical characteristics, angiographic findings, and baseline lipid status of 1,000 consecutive unselected patients with angiographically confirmed CAD.


METHODS
Between April 2001 and July 2002, we obtained informed consent and prospectively collected clinical characteristics, fasting lipid profiles, and angiographic results from 1,000 sequential patients with CAD confirmed by angiography.


RESULTS
In these patients with confirmed CAD, 78% had history of hyperlipidemia. Although 62% were receiving lipid-lowering therapy, only 46% had a low-density lipoprotein target of < 100 mg/dl, and only 20% had achieved all four National Cholesterol Education Program-recommended lipid targets.


CONCLUSIONS
Better strategies to ensure optimal lipid levels are required. One such method using computerized workflow is being evaluated in this population.
Khanal
Sanjaya
S
Henry Ford Heart and Vascular Institute, Detroit, Michigan 48202, USA. skhanal1@hfhs.org
Obeidat
Omar
O
Lu
Mei
M
Douthat
Lori
L
Hudson
Michael P
MP
Greenbaum
Adam B
AB
Kugelmass
Aaron
A
Weaver
W Douglas
WD
D000368:Aged; D015415:Biomarkers / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood / Q000187:drug effects; D008078:Cholesterol, LDL / Q000097:blood / Q000187:drug effects; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000097:blood / Q000000981:diagnostic imaging* / Q000188:drug therapy; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000592:standards / Q000627:therapeutic use; D006949:Hyperlipidemias / Q000097:blood / Q000000981:diagnostic imaging* / Q000188:drug therapy; D000960:Hypolipidemic Agents / Q000592:standards / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D011446:Prospective Studies; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood
D015415:Biomarkers; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D000960:Hypolipidemic Agents; D014280:Triglycerides