Predictors of cardiovascular death in patients with a left ventricular restrictive filling pattern of the mitral inflow.
The survival, clinical and echocardiographic variables and the predictors of cardiovascular death were determined for a group of 168 patients (mean age 63+/-13 years; 65 females; mean left ventricular ejection fraction 32+/-10%) with restrictive filling of the left ventricle and depressed systolic function after a mean follow-up period of 2.7+/-1 years. Shorter deceleration time (DT) of the mitral inflow was the only variable significantly different between survivors and nonsurvivors (p<0.05) and the only predictor of death found by multivariate logistic regression analysis (odds ratio 2.2, 95% confidence interval 1.7-3.6). In this patient population, a DT of the early wave of the mitral inflow <140 ms identified the patients with the highest risk of cardiac death. DT is a practical echocardiographic parameter for risk stratification of patients with significant left ventricular systolic dysfunction and restrictive filling of the left ventricle.
Boccalandro
Fernando
F
Odessa Heart Institute, Odessa, Tex. 79761, USA. Fernando.Boccalandro@uth.tmc.edu
Loghin
Catalin
C
Seung-Ho
Kang
K
Barasch
Eddy
E
D002313:Cardiomyopathy, Restrictive / Q000401:mortality* / Q000503:physiopathology; D004452:Echocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000503:physiopathology*; D015999:Multivariate Analysis; D011237:Predictive Value of Tests; D013781:Texas / Q000453:epidemiology; D018487:Ventricular Dysfunction, Left / Q000401:mortality* / Q000503:physiopathology