The maturing of the human embryonic stem cell transcriptome profile.
Several recent reports used microarray, serial analysis of gene expression (SAGE), and expressed sequence tags (EST) strategies to characterize the human embryonic stem cell transcriptome and those of their differentiated derivatives. All three approaches yielded valuable data and highlight the fact that a large percentage of genes remain uncharacterized in these cells representative of early human development.
Robson
Paul
P
Stem Cell and Developmental Biology, Genome Institute of Singapore and Department of Biological Sciences, National University of Singapore, 60 Biopolis Street, 02-01, Genome Building, Singapore 138672. robsonp@gis.a-star.edu.sg
D019992:Databases as Topic; D004622:Embryo, Mammalian / Q000166:cytology*; D020224:Expressed Sequence Tags; D015723:Gene Library; D005821:Genetic Techniques; D016678:Genome; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis; D040081:Protein Array Analysis / Q000379:methods; D020543:Proteome; D012333:RNA, Messenger / Q000378:metabolism*; D012984:Software; D013234:Stem Cells / Q000166:cytology*
D020543:Proteome; D012333:RNA, Messenger