title: Cervical artery dissection: An atypical presentation with Ehlers-Danlos-like collagen pathology?
abstract: The authors took skin biopsies of the macroscopically normal skin of seven consecutive patients with spontaneous cervical artery dissection (SCAD). Histologically, alterations of the collagen and elastic fiber networks were found in six patients. In five, the histologic, immunohistochemical, and ultrastructural changes were similar to those usually found in Ehlers-Danlos syndrome (EDS). This suggests that SCAD is frequently associated with the dermal alterations seen in EDS.
authors.affiliation: Department de Neurologie, Centre Hospitalier de Luxembourg, Luxembourg. ulbricht@macnews.de
authors.forename: D
authors.initials: D
authors.lastname: Ulbricht
authors.forename: N J
authors.initials: NJ
authors.lastname: Diederich
authors.forename: T
authors.initials: T
authors.lastname: Hermanns-Lê
authors.forename: R J
authors.initials: RJ
authors.lastname: Metz
authors.forename: F
authors.initials: F
authors.lastname: Macian
authors.forename: G E
authors.initials: GE
authors.lastname: Piérard
mesh_terms: D000328:Adult; D001706:Biopsy; D020215:Carotid Artery, Internal, Dissection / Q000175:diagnosis / Q000473:pathology*; D004535:Ehlers-Danlos Syndrome / Q000473:pathology; D004547:Elastic Tissue / Q000473:pathology / Q000648:ultrastructure; D005260:Female; D024022:Fibrillar Collagens / Q000648:ultrastructure*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology* / Q000648:ultrastructure; D020217:Vertebral Artery Dissection / Q000175:diagnosis / Q000473:pathology*
chemical_list: D024022:Fibrillar Collagens