Construction of chiral quaternary carbon centers by Pd-catalyzed asymmetric allylic substitution with P,N-1,1'-ferrocene ligands.
A chiral quaternary carbon center on allyl substrates was constructed by Pd-catalyzed allylic alkylation reaction in good to high regio- and enantioselectivities for a wide range of substrates for the first time. [reaction: see text]
Hou
Xue-Long
XL
State Key Laboratory of Organometallic Chemistry and Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, The Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, P. R. China. xlhou@mail.sioc.ac.cn
Sun
Na
N