title: 'Double asymmetric induction' as a novel tool for high stereocontrol in Baylis-Hillman reaction.
abstract: The strategy of double asymmetric induction was utilized in Baylis-Hillman reaction for the first time by the coupling of chiral aldehydes with chiral acrylate (1,2:5,6-di-O-isopropylidene-alpha-D-glucofuranose-3-acrylate) to obtain corresponding adducts with high syn diastereoselectivities (de >90%) in moderate to good yields.
authors.affiliation: D-206/B, Discovery Laboratory, Organic Chemistry Division-III Indian Institute of Chemical Technology, Hyderabad 500 007, India. prkgenius@iict.res.in
authors.forename: Palakodety Radha
authors.initials: PR
authors.lastname: Krishna
authors.forename: Rachna
authors.initials: R
authors.lastname: Sachwani
authors.forename: V
authors.initials: V
authors.lastname: Kannan