Stereotactic radiosurgery for patients with solid brain metastases: current status.
The goal of this article is to provide a contemporary update on the use of stereotactic radiosurgery (SRS) for the treatment of intracranial metastatic disease. We discuss the rationale for employing SRS in brain metastases and describe the critical factors that predict outcome. We highlight the main clinical indications for SRS including treatment of recurrent brain metastases after previous whole brain radiation therapy (WBRT), as a boost after WBRT, and as sole therapy for newly diagnosed tumors. For each clinical scenario, we offer a treatment algorithm based on our clinical experience. The article also addresses the most common complications associated with SRS and their treatment.
Warnick
Ronald E
RE
Department of Neurosurgery, The Neuroscience Institute, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267-0515, USA. editor@mayfieldclinic.com
Darakchiev
Borimir J
BJ
Breneman
John C
JC
D001932:Brain Neoplasms / Q000556:secondary* / Q000601:surgery*; D003131:Combined Modality Therapy; D006801:Humans; D016634:Radiosurgery / Q000379:methods*