title: Cellular and physiological effects of probiotics and prebiotics.
abstract: We review the present knowledge on the biological mechanisms of action of probiotics and prebiotics. They include direct effects in the intestinal lumen or on intestinal or immune cells, and indirect mechanisms through modulation of the endogenous microflora (composition or functions such as butyrate production) or of the immune system.
authors.affiliation: Gastroenterology Department, European Hospital Georges Pompidou, Assistance Publique des Hôpitaux de Paris & Paris V University, France. philippe.marteau@egp.ap-hop-paris.fr.
authors.forename: Philippe
authors.initials: P
authors.lastname: Marteau
authors.forename: Philippe
authors.initials: P
authors.lastname: Seksik
authors.forename: Patricia
authors.initials: P
authors.lastname: Lepage
authors.forename: Joël
authors.initials: J
authors.lastname: Doré
mesh_terms: D000818:Animals; D002087:Butyrates / Q000378:metabolism / Q000494:pharmacology; D016207:Cytokines / Q000378:metabolism; D004064:Digestive System / Q000187:drug effects / Q000276:immunology / Q000382:microbiology; D006801:Humans; D007107:Immune System / Q000187:drug effects / Q000276:immunology; D007111:Immunity, Cellular / Q000187:drug effects / Q000276:immunology; D009844:Oligosaccharides / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use; D019936:Probiotics / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D002087:Butyrates; D016207:Cytokines; D009844:Oligosaccharides