Molecular cloning of toxins expressed by the venom gland of Lasiodora sp.
The present work describes the identification of toxins expressed by the venom gland of the spider Lasiodora sp. The toxins LTx1, LTx2 and LTx3 were identified by the screening of a cDNA library. These toxins showed significant similarity at the amino acid level with spider toxins from Lasiodora parahybana, Eurypelma californicum, Brachypelma smithii, Selenocosmia huwena.
Vieira
A L G
AL
Laboratório de Biologia Celular e Molecular, Núcleo de Pesquisa em Ciências Biológicas, Universidade Federal de Ouro Preto, Campus do Morro do Cruzeiro, Ouro Preto, MG 35.400-00, Brazil.
Moura
M B
MB
Babá
E H
EH
Chávez-Olórtegui
C
C
Kalapothakis
E
E
Castro
I M
IM
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D015870:Gene Expression; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D013045:Species Specificity; D013111:Spider Venoms / Q000737:chemistry*; D013112:Spiders / Q000737:chemistry*
C532438:LTx2 neurotoxin, Lasiodora; D013111:Spider Venoms