Autologous skeletal myoblasts for myocardial regeneration.
We overview the current knowledge about the use of skeletal myoblasts in regeneration of infarcted myocardium. Myoblasts are attractive candidates for cell source for cardiomyoplasty in chronic postmyocardial injury as indicated by experimental and initial clinical experience. We also review the recent developments in skeletal myoblasts transplantation techniques with special attention to percutaneous transvenous approach to deliver therapeutic agents into myocardium from the lumen of coronary veins under intravascular guidance.
Siminiak
Tomasz
T
Department of Cardiology, University School of Medical Sciences, District Hospital, Poznań, Poland. tomasz.siminiak@usoms.poznan.pl
Kalmucki
Piotr
P
Kurpisz
Maciej
M
D001145:Arrhythmias, Cardiac / Q000209:etiology; D006328:Cardiac Catheterization; D001026:Coronary Artery Bypass; D019160:Endosonography; D006801:Humans; D032448:Myoblasts, Skeletal; D009200:Myocardial Contraction; D009203:Myocardial Infarction / Q000601:surgery*; D014182:Transplantation, Autologous