title: Pulmonary capillaritis with hemorrhage due to propylthiouracil therapy in a child.
abstract: We report on a case of pulmonary capillaritis with diffuse alveolar hemorrhage in a child due to propylthiouracil (PTU). PTU treatment is a rare cause of pulmonary capillaritis in adults; we report on the first case in a pediatric patient. The treatment of pulmonary capillaritis often requires corticosteroid therapy, other immunosuppressive medications, or withdrawal of the causative agent. Our patient recovered completely after treatment with a limited course of corticosteroids and removal of PTU.
authors.affiliation: Department of Pediatrics, St. Christopher's Hospital for Children, Drexel University College of Medicine, Philadelphia, Pennsylvania 19134, USA.
authors.forename: Anayansi Lasso
authors.initials: AL
authors.lastname: Pirot
authors.forename: Donald
authors.initials: D
authors.lastname: Goldsmith
authors.forename: Judy
authors.initials: J
authors.lastname: Pascasio
authors.forename: Suzanne E
authors.initials: SE
authors.lastname: Beck
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D013956:Antithyroid Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D002196:Capillaries / Q000473:pathology*; D002648:Child; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D006980:Hyperthyroidism / Q000188:drug therapy; D007249:Inflammation; D008168:Lung / Q000098:blood supply*; D008171:Lung Diseases / Q000139:chemically induced* / Q000188:drug therapy; D011441:Propylthiouracil / Q000009:adverse effects* / Q000627:therapeutic use*
chemical_list: D000305:Adrenal Cortex Hormones; D013956:Antithyroid Agents; D011441:Propylthiouracil