Dietary salt, blood pressure, and microalbuminuria.
The relationship between dietary salt, blood pressure, and risk for cardiovascular disease has been debated for decades. Microalbuminuria is a biomarker for both cardiovascular and kidney disease. The presence of microalbuminuria correlates directly with the risk for myocardial infarction and stroke and indicates individuals at risk for the development of progressive kidney disease. Since patients with the metabolic syndrome, diabetes, or chronic kidney disease often are blood pressure salt sensitive, and it is well known that increasing dietary salt may offset both the antihypertensive and antiproteinuric effects of renin-angiotensin system blocking drugs, physicians must consider increased salt intake as a potential modifiable risk factor for progression of chronic kidney disease and possibly even cardiovascular disease.
Weir
Matthew R
MR
Division of Nephrology, University of Maryland Hospital, 22 South Greene Street, Baltimore, MD 21201-1595, USA. mweir@medicine.umaryland.edu
D000419:Albuminuria; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000503:physiopathology*; D006801:Humans; D017673:Sodium Chloride, Dietary
D017673:Sodium Chloride, Dietary