Guanidines as a nitrogen source for direct conversion of epoxides to aziridines.
Direct conversion of epoxides to aziridines was achieved with guanidines as a nitrogen source. Stereochemical inversion at the chiral centers of epoxides was observed without loss of optical purity.
Tsuchiya
Yukiko
Y
Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi, Inage, Chiba 263-8522, Japan.
Kumamoto
Takuya
T
Ishikawa
Tsutomu
T
D001388:Aziridines / Q000138:chemical synthesis*; D004852:Epoxy Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D006146:Guanidines / Q000737:chemistry*; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*
D001388:Aziridines; D004852:Epoxy Compounds; D006146:Guanidines; D009584:Nitrogen