title: 3 Tesla magnetic resonance imaging of the brain in newborns.
abstract: While it has been hypothesized that brain development is abnormal in schizophrenia and other neurodevelopmental disorders, there have been few attempts to study very early brain development in children. Twenty unsedated healthy newborns underwent 3 Tesla magnetic resonance imaging (MRI), including diffusion tensor imaging (DTI). The left ventricle was significantly larger than the right; females had significantly larger ventricles than males. Fractional anisotropy (FA) increased significantly with gestational age in the genu and splenium of the corpus callosum. It is feasible to study brain development in unsedated newborns using 3 T MRI.
authors.affiliation: UNC Schizophrenia Research Center, University of North Carolina, Chapel Hill, NC 27599-7160, USA. jgilmore@med.unc.edu
authors.forename: John H
authors.initials: JH
authors.lastname: Gilmore
authors.forename: Guihua
authors.initials: G
authors.lastname: Zhai
authors.forename: Kathy
authors.initials: K
authors.lastname: Wilber
authors.forename: J Keith
authors.initials: JK
authors.lastname: Smith
authors.forename: Weili
authors.initials: W
authors.lastname: Lin
authors.forename: Guido
authors.initials: G
authors.lastname: Gerig
mesh_terms: D001921:Brain / Q000002:abnormalities* / Q000503:physiopathology; D002552:Cerebral Ventricles / Q000473:pathology; D003337:Corpus Callosum / Q000033:anatomy & histology; D005240:Feasibility Studies; D006801:Humans; D021621:Imaging, Three-Dimensional; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D012559:Schizophrenia / Q000503:physiopathology