Optically active sum frequency generation from molecules with a chiral center: amino acids as model systems.
With amino acids as model systems, optically active sum frequency generation (OA-SFG) was used to probe the chirality of molecules with a chiral center and an intrinsically achiral chromophore in isotropic solution for the first time. Like that of circular dichroism (CD), the OA-SFG's near electronic resonance originates from the extrachromophoric chiral perturbation on the carboxyl chromophore. The difference in the relative strengths of OA-SFG and CD among different amino acids can be explained by the difference in the details of perturbations.
Ji
Na
N
Department of Physics, University of California, and Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.
Shen
Yuen-Ron
YR
D000596:Amino Acids / Q000737:chemistry*; D002942:Circular Dichroism; D008956:Models, Chemical; D055095:Optics and Photonics; D013237:Stereoisomerism
D000596:Amino Acids