title: Synthesis of fused polycycles by 1,4-palladium migration chemistry.
abstract: Novel palladium migration/arylation methodology for the synthesis of complex fused polycycles has been developed, in which one or more sequential Pd-catalyzed intramolecular migration processes involving C-H activation are employed. The chemistry works best with electron-rich aromatics, which is in agreement with the idea that these palladium-catalyzed C-H activation reactions parallel electrophilic aromatic substitution.
authors.affiliation: Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
authors.forename: Qinhua
authors.initials: Q
authors.lastname: Huang
authors.forename: Marino A
authors.initials: MA
authors.lastname: Campo
authors.forename: Tuanli
authors.initials: T
authors.lastname: Yao
authors.forename: Qingping
authors.initials: Q
authors.lastname: Tian
authors.forename: Richard C
authors.initials: RC
authors.lastname: Larock
mesh_terms: D002384:Catalysis; D003500:Cyclization; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D011083:Polycyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D006576:Heterocyclic Compounds, 4 or More Rings; D011083:Polycyclic Compounds; D010165:Palladium