Association between a high BK virus load in urine samples of patients with graft-versus-host disease and development of hemorrhagic cystitis after hematopoietic stem cell transplantation.
BK virus (BKV) load in urine alone or in combination with acute graft-versus-host disease (GVHD) was correlated to development of hemorrhagic cystitis (HC). BKV load in combination with acute GVHD discriminated the best, while BKV and viral load alone, but not GVHD, still showed predictive ability for HC.
Bogdanovic
G
G
Department of Oncology-Pathology, Karolinska Institute, Hudding University Hospital, Stockholm, Sweden.
Priftakis
P
P
Giraud
G
G
Kuzniar
M
M
Ferraldeschi
R
R
Kokhaei
P
P
Mellstedt
H
H
Remberger
M
M
Ljungman
P
P
Winiarski
J
J
Dalianis
T
T
D000328:Adult; D001739:BK Virus / Q000502:physiology*; D002648:Child; D003556:Cystitis / Q000209:etiology*; D006086:Graft vs Host Disease / Q000150:complications* / Q000821:virology; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D027601:Polyomavirus Infections / Q000150:complications / Q000821:virology; D014412:Tumor Virus Infections / Q000150:complications / Q000821:virology; D014556:Urine / Q000821:virology*; D019562:Viral Load