title: [Anticoagulation with bemiparina after intracerebral hemorrhage as complication of bacterial endocarditis on metallic prosthetic valve].
abstract: We present the case of a patient with an intracerebral hemorrhage as complication of an infectious endocarditis (EI) produced by Neisseria sicca on a prosthetic mitral valve. The patient was anticoagulated previously with Acenocumarol as prophylaxis of thrombosis of the prosthetic valve. He was diagnosed as having IE and later he presented neurological symptoms as consequence of several intracerebral hemorrhagic foci. We decided to continue the anticoagulation with sodium heparin followed of Bemiparina and no new hemorrhagic complications nor thrombosis of the valve were observed after three months of the event. We have not found in the literature any case where low molecular weight heparin has been used as method of anticoagulation in these cases beyond two weeks.
authors.affiliation: Servicio de Medicina Interna, Hospital Regional Carlos Haya, Málaga, Spain. amcubo@telefonica.net
authors.forename: A
authors.initials: A
authors.lastname: Muñoz Morente
authors.forename: M A
authors.initials: MA
authors.lastname: Barón Ramos
authors.forename: S
authors.initials: S
authors.lastname: Mateos Fernández
authors.forename: S
authors.initials: S
authors.lastname: López Palmero
authors.forename: J
authors.initials: J
authors.lastname: Villar Jiménez
authors.forename: J M
authors.initials: JM
authors.lastname: Regueira Iglesias
mesh_terms: D002543:Cerebral Hemorrhage / Q000188:drug therapy* / Q000209:etiology; D004697:Endocarditis, Bacterial / Q000150:complications*; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve; D042808:Neisseria sicca; D016870:Neisseriaceae Infections / Q000150:complications*; D016459:Prosthesis-Related Infections / Q000150:complications*
chemical_list: D006495:Heparin, Low-Molecular-Weight; C411345:bemiparin