title: Association between exercise capacity and left ventricular geometry in overweight patients with mild systemic hypertension.
abstract: The purpose of this study was to determine the relation between left ventricular (LV) geometry and exercise capacity in unmedicated, hypertensive patients. Analysis of the data revealed peak oxygen consumption (ml kg(-1) min(-1)) for concentric hypertrophy (corrected mean +/- SE 23.5 +/- 1.2) was significantly less (F = 3.68, p <0.02) than the concentric remodeling (28.1 +/- 1.2) and normal (27.3 +/- 0.6) geometries. The LV geometric pattern was found to be associated with exercise capacity in unmedicated, hypertensive patients, such that patients with concentric hypertrophy showed reduced capacity.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA.
authors.forename: Lee M
authors.initials: LM
authors.lastname: Pierson
authors.forename: Simon L
authors.initials: SL
authors.lastname: Bacon
authors.forename: Andrew
authors.initials: A
authors.lastname: Sherwood
authors.forename: Alan L
authors.initials: AL
authors.lastname: Hinderliter
authors.forename: Michael
authors.initials: M
authors.lastname: Babyak
authors.forename: Elizabeth C D
authors.initials: EC
authors.lastname: Gullette
authors.forename: Robert
authors.initials: R
authors.lastname: Waugh
authors.forename: James A
authors.initials: JA
authors.lastname: Blumenthal
mesh_terms: D004452:Echocardiography; D017079:Exercise Tolerance; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology*; D017379:Hypertrophy, Left Ventricular / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000503:physiopathology*; D010101:Oxygen Consumption