title: Bufadienolides from Drimia robusta and Urginea epigea (Hyacinthaceae).
abstract: Two bufadienolides, 6beta-acetoxy-3beta,8beta,14beta-trihydroxy-12-oxobufa-4,20,22-trienolide and 14beta-hydroxybufa-3,5,20,22-tetraenolide were isolated from the dichloromethane extract of the bulbs of Drimia robusta and the methanol extract of the bulbs of Urginea epigea, respectively. The bulbs of Drimia robusta also yielded several known compounds, 6beta-acetoxy-3beta,8beta,12beta,14beta-tetrahydroxybufa-4,20,22-trienolide (12beta-hydroxyscillirosidin) from the dichloromethane extract and three common aromatic acids, 4-hydroxy-3-methoxybenzoic acid, 3,4-dihydroxybenzoic acid, and trans-3-(4'-hydroxyphenyl)-2-propenoic acid from the ethyl acetate extract.
authors.affiliation: Natural Products Research Group, School of Pure and Applied Chemistry, University of KwaZulu-Natal, Durban 4041, South Africa. Koorbanally@nu.ac.za
authors.forename: Neil A
authors.initials: NA
authors.lastname: Koorbanally
authors.forename: Chantal
authors.initials: C
authors.lastname: Koorbanally
authors.forename: Avinash
authors.initials: A
authors.lastname: Harilal
authors.forename: Dulcie A
authors.initials: DA
authors.lastname: Mulholland
authors.forename: Neil R
authors.initials: NR
authors.lastname: Crouch
mesh_terms: D002018:Bufanolides / Q000737:chemistry* / Q000302:isolation & purification; D003373:Coumaric Acids; D031448:Drimia / Q000737:chemistry; D062385:Hydroxybenzoates / Q000737:chemistry; D019668:Liliaceae / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D011422:Propionates / Q000737:chemistry; D014641:Vanillic Acid / Q000737:chemistry
chemical_list: C442171:12beta-hydroxyscillirosidin; C495467:14beta-hydroxybufa-3,5,20,22-tetraenolide; C495468:6beta-acetoxy-3beta,8beta,14beta-trihydroxy-12-oxobufa-4,20,22-trienolide; D002018:Bufanolides; D003373:Coumaric Acids; D062385:Hydroxybenzoates; D011422:Propionates; C009091:protocatechuic acid; D014641:Vanillic Acid; C495469:p-coumaric acid