title: Role of antiplatelet therapy in cardiovascular disease II: Ischemic stroke.
abstract: The etiology of cerebrovascular disease is heterogeneous, with the majority of strokes being of ischemic origin. Transient ischemic attack is now considered to be an important precursor and long-term risk factor for ischemic stroke. Given the lack of acute therapies for ischemic stroke, current treatments focus on secondary prevention through risk-factor management, pharmacotherapy and interventional approaches. As illustrated in this paper, antiplatelet agents (e.g. clopidogrel, aspirin, dipyridamole) are the cornerstone of therapy for prevention of recurrent ischemic stroke.
authors.affiliation: Department of Cardiology, Naval Medical Center, San Diego, CA 92134, USA. JJCavendish@nmcsd.med.navy.mil
authors.forename: Jeffrey J
authors.initials: JJ
authors.lastname: Cavendish
authors.forename: Steven C
authors.initials: SC
authors.lastname: Cramer
authors.forename: Glenn D
authors.initials: GD
authors.lastname: Graham
mesh_terms: D000328:Adult; D000368:Aged; D002545:Brain Ischemia / Q000188:drug therapy* / Q000517:prevention & control; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D012008:Recurrence; D020521:Stroke / Q000188:drug therapy* / Q000517:prevention & control
chemical_list: D010975:Platelet Aggregation Inhibitors