Highly diastereo- and enantioselective reagents for aldehyde crotylation.
Two new, crystalline solid, storable, and highly enantioselective reagents for aldehyde crotylation have been developed. Both (cis and trans) crotylsilane reagents are easily prepared in bulk, require trivial reaction conditions, and provide the homoallylic alcohol products with near diastereo- and enantiospecificity in many cases.
Hackman
Blaine M
BM
Department of Chemistry, Columbia University, New York, New York 10027, USA.
Lombardi
Pamela J
PJ
Leighton
James L
JL
D000447:Aldehydes / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*
D000447:Aldehydes; D012821:Silanes; C507609:crotylsilane