Down syndrome with morgagni hernia and hypothyroidism.
A rare association of Down syndrome with hypothyroidism and Morgagni type of diaphragmatic defect is described in a one-year-old male child who presented with a history of recurrent chest infections and delayed milestones. He showed obvious features of Down syndrome but was also found to have hypothyroidism on investigations. Morgagni hernia was suspected on lateral chest X- ray and confirmed by CT scan thorax. He responded well to the management, which included surgical repair of the hernia.
Naveed-ur-Rehman
Department of Paediatrics, Shifa College of Medicine, Islamabad. rehman_naveed@hotmail.com
Ahmad
Zaheer
Z
Anwar-ul-Haq
Abbas
Khwaja Ahmad
KA
D004314:Down Syndrome / Q000150:complications*; D006548:Hernia, Diaphragmatic / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007037:Hypothyroidism / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D007223:Infant; D008297:Male; D011014:Pneumonia / Q000188:drug therapy / Q000209:etiology; D012008:Recurrence; D013963:Thyroid Hormones / Q000627:therapeutic use; D013974:Thyroxine / Q000627:therapeutic use
D013963:Thyroid Hormones; D013974:Thyroxine