title: [A case of disseminated tumor from cecal cancer with survival for over 5 years after twice surgical resection and systemic chemotherapy].
abstract: A 66-year-old man underwent a curative operation for cecal cancer on the 30th of November, 1998. Since his CEA level rose in January 2001, computed tomography (CT) revealed a tumor in the abdomen. He underwent a resection of this tumor and disseminated tumors that were diagnosed during the operation. He received systemic chemotherapy (5'-DFUR 600 mg 3x everyday, CPT-11 80 mg/body div every 2 weeks), but the CEA level rose again in August 2003. He was diagnosed with spleen metastasis and underwent splenectomy. The tumor disseminated in the left diaphragm was also resected. After that, he received systemic chemotherapy (5-FU 500 mg/body/week div, levofolinate calcium 250 mg/body/week i.v.) as an outpatient. Peritoneal carcinomatosis from colorectal cancer with distant metastasis, in general, has no indication for an operation. However, if dissemination is located after a sufficient observation period, its resection may be recommended.
authors.affiliation: Dept. of Surgery II, Yamaguchi University School of Medicine.
authors.forename: Takao
authors.initials: T
authors.lastname: Tamesa
authors.forename: Yusaku
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Yoshimura
authors.forename: Naohide
authors.initials: N
authors.lastname: Mori
authors.forename: Shigeru
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Shoichi
authors.initials: S
authors.lastname: Hazama
authors.forename: Akira
authors.initials: A
authors.lastname: Tangoku
authors.forename: Masaaki
authors.initials: M
authors.lastname: Oka
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D002272:Carcinoembryonic Antigen / Q000097:blood; D002430:Cecal Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D005467:Floxuridine / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D000077146:Irinotecan; D002955:Leucovorin / Q000008:administration & dosage; D008297:Male; D009366:Neoplasm Seeding; D010534:Peritoneal Neoplasms / Q000556:secondary* / Q000628:therapy*; D012086:Reoperation
chemical_list: D002272:Carcinoembryonic Antigen; D005467:Floxuridine; D000077146:Irinotecan; D002955:Leucovorin; D005472:Fluorouracil; C025034:doxifluridine; D002166:Camptothecin