title: The search for new beta-cell sources.
abstract: Type 1 diabetes affects an estimated 150 million people worldwide and results from an autoimmune-mediated destruction of insulin-producing beta-cells. In the United States alone more than 16 million people are affected by this disease and it is estimated that spending for diabetes management accounts for one out of every eight healthcare dollars. In this context, scientists are proposing novel therapeutic strategies that might allow a perfect glycemic control of most patients with diabetes.
authors.affiliation: Laboratory of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of the Basque Country, Vitoria-Gasteiz, 01002, Spain.
authors.forename: Gorka
authors.initials: G
authors.lastname: Orive
authors.forename: Alicia R
authors.initials: AR
authors.lastname: Gascón
authors.forename: Rosa M
authors.initials: RM
authors.lastname: Hernández
authors.forename: José Luis
authors.initials: JL
authors.lastname: Pedraz
mesh_terms: D000818:Animals; D003922:Diabetes Mellitus, Type 1 / Q000473:pathology* / Q000628:therapy*; D006801:Humans; D006943:Hyperglycemia / Q000628:therapy; D007328:Insulin / Q000627:therapeutic use; D007515:Islets of Langerhans / Q000166:cytology*; D016381:Islets of Langerhans Transplantation / Q000379:methods*; D051379:Mice; D013552:Swine; D014183:Transplantation, Heterologous
chemical_list: D007328:Insulin