title: Neuronal pathway finding: from neurons to initial neural networks.
abstract: Neuronal pathway finding is crucial for structured cellular organization and development of neural circuits within the nervous system. Neuronal pathway finding within the visual system has been extensively studied and therefore is used as a model to review existing knowledge regarding concepts of this developmental process. General principles of neuron pathway finding throughout the nervous system exist. Comprehension of these concepts guides neuroscience nurses in gaining an understanding of the developmental course of action, the implications of different anomalies, as well as the theoretical basis and nursing implications of some provocative new therapies being proposed to treat neurodegenerative diseases and neurologic injuries. These therapies have limitations in light of current ethical, developmental, and delivery modes and what is known about the development of neuronal pathways.
authors.affiliation: University of Washington School of Nursing, Seattle, WA, USA. graymtr@u.washington.edu
authors.forename: Cecelia I
authors.initials: CI
authors.lastname: Roscigno
mesh_terms: D000344:Afferent Pathways / Q000033:anatomy & histology / Q000502:physiology; D001369:Axons / Q000502:physiology / Q000648:ultrastructure; D003337:Corpus Callosum / Q000033:anatomy & histology / Q000502:physiology; D023882:Dominance, Ocular / Q000502:physiology; D020439:Growth Cones / Q000502:physiology / Q000648:ultrastructure; D006801:Humans; D020647:Lateral Thalamic Nuclei / Q000033:anatomy & histology / Q000502:physiology; D008959:Models, Neurological; D009415:Nerve Net / Q000033:anatomy & histology / Q000502:physiology*; D009422:Nervous System Diseases / Q000628:therapy; D009434:Neural Pathways / Q000033:anatomy & histology / Q000502:physiology*; D009474:Neurons / Q000502:physiology* / Q000648:ultrastructure; D024802:Nurse's Role; D009897:Optic Chiasm / Q000033:anatomy & histology / Q000502:physiology; D012165:Retinal Ganglion Cells / Q000502:physiology / Q000648:ultrastructure; D013477:Superior Colliculi / Q000033:anatomy & histology / Q000502:physiology; D014795:Visual Pathways / Q000502:physiology / Q000648:ultrastructure