title: Lack of toxic effects following acute overdose of cellcept (mycophenolate mofetil).
abstract: Mycophenolate mofetil is an immunosuppressive drug used for prevention of graft rejection following solid organ transplant and for treatment of autoimmune disorders. We report a case of a 24-year-old female with lupus nephritis that presented following ingestion of 10 grams of mycophenolate in a suicide gesture. Serum levels confirmed ingestion. The patient was treated with decontamination and supportive care and recovered with no adverse effect.
authors.affiliation: Rocky Mountain Poison and Drug Center-Denver Health, Division of Emergency Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA.
authors.forename: Vikhyat S
authors.initials: VS
authors.lastname: Bebarta
authors.forename: Kennon
authors.initials: K
authors.lastname: Heard
authors.forename: Craig
authors.initials: C
authors.lastname: Nadelson
mesh_terms: D000328:Adult; D000931:Antidotes / Q000627:therapeutic use; D001772:Blood Cell Count; D002606:Charcoal / Q000627:therapeutic use; D062787:Drug Overdose; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007166:Immunosuppressive Agents / Q000506:poisoning* / Q000627:therapeutic use; D008181:Lupus Nephritis / Q000188:drug therapy; D009173:Mycophenolic Acid / Q000031:analogs & derivatives* / Q000506:poisoning* / Q000627:therapeutic use; D013406:Suicide, Attempted
chemical_list: D000931:Antidotes; D007166:Immunosuppressive Agents; D002606:Charcoal; D009173:Mycophenolic Acid