Familial lipomyelomeningocele: a further report.
Lipomyelomeningocele is a form of spina bifida occulta with a distinct pathogenesis that differentiates it from open neural tube defects. Familial forms are rare and the condition may be polygenic. We report on 2 affected siblings with similar lesions and raise the possibility of an autosomal recessive pattern of inheritance with implications for genetic counselling.
Kannu
Peter
P
Northern Regional Genetics Service, Auckland Hospital, Auckland, New Zealand.
Furneaux
Christopher
C
Aftimos
Salim
S
D002675:Child, Preschool; D005192:Family Health; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D035781:Siblings; D016136:Spina Bifida Occulta / Q000235:genetics / Q000473:pathology*