title: [Immunological safety and sensitizing effect of an MB-7-based vaccine against hepatitis A].
abstract: The influence of a vaccine based on the MB-7 strain of hepatitis A virus (VP-MB-7) designed at the "Vector" Center of Virology and Biotechnology was studied. VP-MB-7 was found to provoke no allergic response and to have an activating effect on the specific and non-specific responses of cell and humoral immunity similar to those evoked by hepatitis A vaccine "Hep-A-in Vac".
authors.forename: M A
authors.initials: MA
authors.lastname: Smerdova
authors.forename: S V
authors.initials: SV
authors.lastname: Usova
authors.forename: M P
authors.initials: MP
authors.lastname: Smolina
authors.forename: S V
authors.initials: SV
authors.lastname: Netesov
authors.forename: A G
authors.initials: AG
authors.lastname: Maĭdaniuk
authors.forename: M A
authors.initials: MA
authors.lastname: Muntianova
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Nemtsov
authors.forename: N I
authors.initials: NI
authors.lastname: Kriuk
authors.forename: V V
authors.initials: VV
authors.lastname: Iashin
authors.forename: L G
authors.initials: LG
authors.lastname: Karpovich
authors.forename: T V
authors.initials: TV
authors.lastname: Kalashnikova
mesh_terms: D000818:Animals; D002452:Cell Count; D004353:Drug Evaluation, Preclinical; D006168:Guinea Pigs; D006506:Hepatitis A / Q000097:blood / Q000517:prevention & control*; D035922:Hepatitis A Antibodies / Q000096:biosynthesis*; D022362:Hepatitis A Vaccines / Q000008:administration & dosage* / Q000276:immunology*; D017957:Hepatitis A Virus, Human / Q000276:immunology*; D007111:Immunity, Cellular; D018655:Lymphocyte Count; D051379:Mice; D008807:Mice, Inbred BALB C; D013154:Spleen / Q000276:immunology; D016176:T-Lymphocyte Subsets / Q000276:immunology; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D014611:Vaccination
chemical_list: D035922:Hepatitis A Antibodies; D022362:Hepatitis A Vaccines