Posttranslational modifications of alpha-tubulin of Toxoplasma gondii.
The posttranslational modifications of alpha-tubulin of Toxoplasma gondii were characterized by antibodies and biochemical analysis of the carboxy-terminal peptide. Alpha-Tubulin is acetylated and glutamylated. Side chains with up to three glutamate residues are linked to Glu445 of T. gondii alpha-tubulin. The data suggest that the site of glutamylation on alpha-tubulin is conserved over a broad range of species.
Plessmann
Uwe
U
Department of Biochemistry, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.
Reiter-Owona
Ingrid
I
Lechtreck
Karl-Ferdinand
KF
D000595:Amino Acid Sequence; D000818:Animals; D013058:Mass Spectrometry; D008969:Molecular Sequence Data; D011499:Protein Processing, Post-Translational; D017422:Sequence Analysis, DNA; D014122:Toxoplasma / Q000378:metabolism*; D014404:Tubulin / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*
D014404:Tubulin