title: Solitary pulmonary nodules: a comparative study evaluated with contrast-enhanced dynamic MR imaging and CT.
abstract: OBJECTIVE
  The aim of this prospective study was to compare the diagnostic performances of dynamic MR imaging and CT for the differentiation of benign and malignant solitary pulmonary nodules (SPNs).
  
  
  METHODS
  Eighty-one patients with SPNs (32 malignant, 49 benign) underwent dynamic MR imaging (n=31), dynamic CT (n=27), or both (n=23). The degree of peak enhancement of benign and malignant SPNs was compared on both dynamic MR imaging and CT. Receiver operating characteristic (ROC) analysis was performed to compare the diagnostic performances of dynamic MR imaging and CT.
  
  
  RESULTS
  The malignant SPNs revealed significantly greater degrees of peak enhancement on dynamic MR imaging (mean +/- SD [p%SI] 131.2 +/- 46.1 versus 54.2 +/- 45.3; range [p%SI] 82.6-260.0 versus -0.7-171.7; P <0.0001) and CT (mean +/- SD [DMI] 37.8 +/- 15.1 versus 17.9 +/- 21.8; range [DMI] 14.1-68.2 versus -5.4-107.6; P=0.0004). Although dynamic MR imaging was somewhat superior to dynamic CT, the diagnostic performances of the 2 modalities based on ROC analysis were not statistically significant.
  
  
  CONCLUSIONS
  Dynamic MR imaging and CT seem to be equally well suited for the differentiation between benign and malignant SPNs.
authors.affiliation: Department of Radiology, Inha University Hospital, Incheon, Republic of Korea.
authors.forename: Jeong Ho
authors.initials: JH
authors.lastname: Kim
authors.forename: Hyung-Jin
authors.initials: HJ
authors.lastname: Kim
authors.forename: Kyung-Hee
authors.initials: KH
authors.lastname: Lee
authors.forename: Kwang Ho
authors.initials: KH
authors.lastname: Kim
authors.forename: Hong Lyeol
authors.initials: HL
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted; D007472:Iohexol; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012372:ROC Curve; D011856:Radiographic Image Enhancement / Q000379:methods; D012680:Sensitivity and Specificity; D003074:Solitary Pulmonary Nodule / Q000175:diagnosis* / Q000000981:diagnostic imaging; D036542:Tomography, Spiral Computed / Q000706:statistics & numerical data
chemical_list: D003287:Contrast Media; D007472:Iohexol; D019786:Gadolinium DTPA