Impact of body mass index on in vitro fertilization outcomes.
OBJECTIVE
To determine if body mass index (BMI) impacts IVF outcome.


METHODS
Retrospective, cohort study. Main outcome measure was number of oocytes obtained.


RESULTS
BMI did not correlate with the prestimulation parameters. There was a significant positive correlation between BMI and the number of follicles on ultrasound prior to egg retrieval. A threshold analysis revealed a significant change in parameters at a BMI > 24 kg/m2. Patients with BMI > 24 kg/m2 demonstrated a significant increase in the number of follicles after stimulation (p = 0.03) and a comparative decrease in the number ampules of gonadotropins used (p = 0.04) and days of stimulation required (p = 0.01).


CONCLUSIONS
These data demonstrated that an elevated BMI significantly correlates with the number of follicles, days of stimulation, and number of ampules of gonadotropins used. Further correlation to an actual increase in number of oocytes and pregnancy rates may be limited by insufficient power in this study.
Frattarelli
John L
JL
Department of Obstetrics and Gynecology, Tripler Army Medical Center, Honolulu, Hawaii 96859-5000, USA. john.frattarelli@amedd.army.mil
Kodama
Catherine Lee
CL
D000328:Adult; D015992:Body Mass Index; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods; D006801:Humans; D009865:Oocytes / Q000166:cytology*; D006080:Ovarian Follicle / Q000166:cytology; D012044:Regression Analysis; D012189:Retrospective Studies; D016896:Treatment Outcome