title: [Aneurysmal rupture during embolization with Guglielmi detachable coils].
abstract: OBJECTIVE
  The purpose of this study is to determinate the frequency, causes, management and outcome of aneurysmal rupture occurring during embolization. We present our experience with this severe and feared complication.
  
  
  METHODS
  We retrospectively reviewed 314 acute cerebral aneurysms that were treated with endovascular coiling. These patients were identified and the management and outcomes were recorded. The literature was reviewed.
  
  
  RESULTS
  Six patients had an intraprocedural aneurysmal rupture. This complication occurred sporadically. Prevalence was 1.9%. Of these six, four were women and two were men. The mean age was 68 years (range: 43-74 years). Four aneurysms were located in the anterior circulation and two in the posterior circulation. Perforation occurred during microcatheterization of the aneurysm in one case and during coil deposition in five cases. In these five patients, aneurysmal rupture resulted from detachment of the first coil in three patients and detachment of the third and last coil in two patients. Hemodynamic changes were noted for one patient. The Glasgow Outcome Scale score at last follow-up examination was 1 in three patients and 3 in one patient (fair recovery). Mortality was 33% and morbidity was 16.7%.
  
  
  CONCLUSIONS
  Aneurysmal perforation during embolization is a rare event (1.8 to 4.4%). When perforation is recognized, embolization can be completed immediately with further coil deposition and reversal of anticoagulation therapy.
authors.affiliation: Service de Neurochirurgie, CHU Nord, Amiens. jojo.peltier@caramail.com
authors.forename: J
authors.initials: J
authors.lastname: Peltier
authors.forename: A
authors.initials: A
authors.lastname: Nowtash
authors.forename: P
authors.initials: P
authors.lastname: Toussaint
authors.forename: C
authors.initials: C
authors.lastname: Desenclos
authors.forename: H
authors.initials: H
authors.lastname: Deramond
authors.forename: D
authors.initials: D
authors.lastname: Le Gars
mesh_terms: D000328:Adult; D000368:Aged; D017542:Aneurysm, Ruptured / Q000209:etiology* / Q000628:therapy; D004621:Embolization, Therapeutic / Q000009:adverse effects* / Q000295:instrumentation; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000209:etiology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors