[Comparison of a rapid antigen test and cultures for diagnosis of meningitis in children].
Fourteen pediatric patients diagnosed as bacterial meningitis between August 1997 and April 2002 were enrolled in this study. Both rapid antigen detection test, Slidex Meningite 5 Kit (Biomerieux) and culture were performed using cerebrospinal fluids (CSF). H. influenzae was isolated from 11 samples and was the most frequently isolated bacteria, followed by S. pneumoniae from 4 samples and enteric bacteriae from 2 samples. Five out of six samples with positive result by culture were also positive by the rapid antigen test. Gram-negative rod was identified in smear specimens of CSF from all these 5 samples. Significance of the rapid antigen test should be recognized under drug resistance of those bacteriae are increasing.
Hashikita
Giichi
G
Department of Central Clinical Laboratory, Saitama Medicine School Hospital, 38 Morohongo, Moroyama-machi, Iruma-gun, Saitama 350 0495, Japan.
Kishi
Etsuko
E
Takahashi
Shun
S
Kawamura
Toru
T
Tachi
Yoshimi
Y
Koyama
Sachie
S
Suto
Yukie
Y
Itabashi
Akira
A
Yamazaki
Tsutomu
T
Harashima
Hiroko
H
Uehara
Suzuko
S
Sasaki
Nozomu
N
Maesaki
Sigefumi
S
D000328:Adult; D000942:Antigens, Bacterial / Q000032:analysis*; D002555:Cerebrospinal Fluid / Q000382:microbiology*; D002648:Child; D006801:Humans; D007158:Immunologic Techniques; D007159:Immunologic Tests; D016920:Meningitis, Bacterial / Q000175:diagnosis*; D011933:Reagent Kits, Diagnostic / Q000592:standards
D000942:Antigens, Bacterial; D011933:Reagent Kits, Diagnostic