Alpha-arylsulfanyl-alpha-fluoro carbenoids: their novel chemistry and synthetic applications.
The bromine-magnesium exchange reactions of arylthiobromodifluoromethanes with Grignard reagents have been studied. Upon trapping with electrophiles, alkyl aryl sulfides and ketenedithioacetals are obtained. The reaction is proposed to occur via novel alpha-arylsulfanyl-alpha-fluoro carbenoids. The first examples of arylthiomethane multipole synthons are also reported. [reaction: see text]
Pohmakotr
Manat
M
Department of Chemistry, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok 10400, Thailand. scmpk@mahidol.ac.th
Ieawsuwan
Winai
W
Tuchinda
Patoomratana
P
Kongsaeree
Palangpon
P
Prabpai
Samran
S
Reutrakul
Vichai
V