title: Paraplegia and sensory deficit caused by angiotropic large cell lymphoma.
abstract: We report a case of angiotropic large cell lymphoma (ALCL) with central system involvement in which there was initially an isolated spinal cord stroke with paraplegia. MR imaging of the spinal cord demonstrated increased signal intensity in the center of the cord on T2-weighted images and subsequently a cerebral lesion in the right temporal lobe. The diagnosis of ALCL was established by brain biopsy. An enlarged spinal cord with enhancement after administration of contrast material and increased signal intensity on T2-weighted images, while not specific for ALCL, may be the first imaging findings of that disease.
authors.affiliation: Department of Neuroradiology, University François Rabelais, Centre Hospitalier Bretonneau, 2 Boulevard Tonnellé 37044 Tours Cedex, France.
authors.forename: Marc
authors.initials: M
authors.lastname: Legeais
authors.forename: Sophie
authors.initials: S
authors.lastname: Gallas
authors.forename: Jean Philippe
authors.initials: JP
authors.lastname: Cottier
authors.forename: Denis
authors.initials: D
authors.lastname: Herbreteau
mesh_terms: D000368:Aged; D001706:Biopsy; D001921:Brain / Q000473:pathology; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008279:Magnetic Resonance Imaging; D010264:Paraplegia / Q000209:etiology*; D012678:Sensation Disorders / Q000209:etiology*; D013116:Spinal Cord / Q000098:blood supply*; D014652:Vascular Diseases / Q000209:etiology*