title: [Urachal carcinoma treated with neoadjuvant intra-arterial chemotherapy: a case report].
abstract: A 43-year-old man visited our clinic with gross hematuria. Ultrasonography and computed tomography demonstrated a tumor at the bladder dome. Cold punch biopsy revealed well-differentiated adenocarcinoma and stage III A urachal carcinoma was diagnosed. Neoadjuvant intra-arterial chemotherapy with cisplatin, adriamycin and angiotensin II was performed and 40% reduction of tumor size was noted 3 weeks after this therapy. En bloc segmental resection was performed. Augmentation ilealcystoplasty was subsequently performed to secure bladder capacity. Adjuvant chemotherapy (UFT) was given for 1 year. Cystolithotomy and closure of ventral hernia were required 10 years after radical surgery for postoperative complications. The patient has survived 12 years with no evidence of local recurrence or distant metastasis.
authors.affiliation: Department of Urology, Kure Kyousai Hospital.
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Seiichi
authors.initials: S
authors.lastname: Itoh
authors.forename: Naoki
authors.initials: N
authors.lastname: Mitsuhata
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D017024:Chemotherapy, Adjuvant; D004334:Drug Administration Schedule; D004338:Drug Combinations; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D005641:Tegafur / Q000008:administration & dosage*; D014497:Urachus; D014498:Uracil / Q000008:administration & dosage*
chemical_list: D000970:Antineoplastic Agents; D004338:Drug Combinations; C096910:UFT(R) drug; D005641:Tegafur; D014498:Uracil