title: [The comparison of the result of exercise bronchoprovocation test and methacholine bronchoprovocation test in athletes].
abstract: The excess contraction respond of the bronchiols to the specific and non-specific agent is called bronchial hyperresponsiveness. In our study we compared the result of exercise bronchoprovocation test and methacholine bronchoprovocation test in athletes (group I) and in sedentary subjects (group II). The subjects that their age, height, weight and environmental status of the test room (temperature and humidity) were not statistically different, they gave statistically different respond to the methacholine bronchoprovocation test (p< 0.05). Their respond to exercise bronchoprovocation test was similar and there was no statistically difference between two groups (p> 0.05). In group I, there was a correlation in the result of exercise bronchoprovocation test and methacholine bronchoprovocation test (r= 0.60, p< 0.05), but in group II there was no correlation in this two tests. The parameters that we use for evaluation of the allergic status (total IgE, eosinophil count, number of atopic subject in groups) were not statistically different (p> 0.05). In both two groups there was a statistically different respond in the result of exercise bronchoprovocation test and methacholine bronchoprovocation test. These findings suggests that methacholine bronchoprovocation test is a more sensitive test for the diagnosis of BHR in athletes and sedantery subjects than exercise bronchoprovocation test.
authors.affiliation: Department of Physiology, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey. udal@cumhuriyet.edu.tr
authors.forename: Uğur
authors.initials: U
authors.lastname: Dal
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Akkurt
authors.forename: Sena
authors.initials: S
authors.lastname: Erdal
mesh_terms: D000328:Adult; D001250:Asthma, Exercise-Induced / Q000175:diagnosis* / Q000503:physiopathology; D016535:Bronchial Hyperreactivity / Q000175:diagnosis* / Q000503:physiopathology; D001985:Bronchial Provocation Tests / Q000379:methods*; D016085:Bronchoconstrictor Agents; D016022:Case-Control Studies; D005080:Exercise Test / Q000379:methods*; D006801:Humans; D008168:Lung / Q000187:drug effects* / Q000502:physiology; D008297:Male; D016210:Methacholine Chloride; D013177:Sports
chemical_list: D016085:Bronchoconstrictor Agents; D016210:Methacholine Chloride