Nerve growth factor involvement in the visual system: implications in allergic and neurodegenerative diseases.
The purpose of this review is to outline the main role of nerve growth factor (NGF) in the visual system and particularly in the ocular surface in physiological and pathological conditions. The present review of experimental and clinical studies will highlight old and recent strategies for treating ocular surface and tear disorders with NGF.
Micera
Alessandra
A
CIR Laboratorio di Oftalmologia, Campus Bio-Medico and Fondazione GB Bietti, Rome, Italy.
Lambiase
Alessandro
A
Aloe
Luigi
L
Bonini
Sergio
S
Levi-Schaffer
Francesca
F
Bonini
Stefano
S
D005128:Eye Diseases / Q000276:immunology / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D006967:Hypersensitivity / Q000473:pathology / Q000503:physiopathology*; D020932:Nerve Growth Factor / Q000378:metabolism*; D019636:Neurodegenerative Diseases / Q000473:pathology / Q000503:physiopathology*; D009799:Ocular Physiological Phenomena; D020800:Receptor, Nerve Growth Factor; D020917:Receptor, trkA / Q000378:metabolism; D017475:Receptors, Nerve Growth Factor / Q000378:metabolism
D020800:Receptor, Nerve Growth Factor; D017475:Receptors, Nerve Growth Factor; D020932:Nerve Growth Factor; D020917:Receptor, trkA