[Isolation and elucidation of antioxidant constituents from acetone extract in root of Scutellaria rehderiana].
OBJECTIVE
To isolatate and elucidate the antioxidant constituents from acetone extract of Scutellaria rehderiana.


METHODS
Chemical constituents were isolated by several column chromatographies and their structures were elucidated on the basis of standard compounds and spectral analysis.


RESULTS
Five compounds, oroxylin A, wogonin, baicalein, ganhuangenin, ganhuangemin were isolated from acetone extract of S. rehderiana. Baicalin was obtained from methanol extract of S. rehderiana.


CONCLUSIONS
Ganhuangemin was isolated from the plant for the first time. Baicalein and ganhuangenin have stronger antioxidant activity than that of BHT (butylated hydroxytoluene).
Su
Ya-lun
YL
Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. suyalun@imm.ac.cn
Huang
Yu
Y
Chen
Zhen-yu
ZY
D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D044950:Flavanones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D031363:Scutellaria / Q000737:chemistry*
D000975:Antioxidants; D044950:Flavanones; D005419:Flavonoids; C497484:ganhuangemin; C006680:baicalein; C047101:ganhuangenin; C085514:wogonin