title: [Redox status in HIV+ patients under HAART].
abstract: Oxidative stress decreases immune defences and is also suggested to participate in the activation of HIV virus replication. That is why we decided to explore some biomarkers of oxidative stress (reduced glutathione, lipoperoxides, true malondialdehyde and vitamin C) in 20 HIV positive patients whose HIV replication was determined by measurement of RNA viral load. Reduced glutathione is decreased in HIV positive patients, without correlation with the viral load. The patients mean content of lipoperoxides is twice that of controls but with such a large range that there is no statistical difference.
authors.affiliation: Fédération de biochimie, hôpital E. Herriot, Lyon. francoise.flourie@chu.lyon
authors.forename: F
authors.initials: F
authors.lastname: Flourié
authors.forename: K
authors.initials: K
authors.lastname: Arab
authors.forename: M C
authors.initials: MC
authors.lastname: Gagnieu
authors.forename: J C
authors.initials: JC
authors.lastname: Tardy
authors.forename: F
authors.initials: F
authors.lastname: Jeanblanc
authors.forename: J M
authors.initials: JM
authors.lastname: Livrozet
authors.forename: J P
authors.initials: JP
authors.lastname: Steghens
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D006679:HIV Seropositivity / Q000188:drug therapy* / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged; D010084:Oxidation-Reduction; D018384:Oxidative Stress