title: [Effects of vitamin D on bone quality].
abstract: The degree of increase BMD (bone mineral density) alone fails to account for the broader effectiveness of vitamin D in reducing the risk of fractures related to osteoporosis. The concept of bone strength also has evolved, integrating those traditional measures of bone quantity (mass) with more recently examined components of bone quality, for example, bone micro-architecture, degree of mineralization, accumulation of micro-damage, and bone turnover. In this review, the effects of vitamin D on bone quality, especially, on bone micro-architecture and degree of mineralization will be discussed.
authors.affiliation: Pharmaceutical Discovery Research Laboratories, Institute for Bio-medical Research Teijin Pharma Limited.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Azuma
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Harada
authors.forename: Seiichi
authors.initials: S
authors.lastname: Ishizuka
authors.forename: Takashi
authors.initials: T
authors.lastname: Kamimura
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000187:drug effects / Q000502:physiology*; D002113:Calcification, Physiologic / Q000187:drug effects; D006801:Humans; D051381:Rats; D014807:Vitamin D / Q000494:pharmacology*
chemical_list: D014807:Vitamin D