title: T2rho-weighted contrast in MR images of the human brain.
abstract: In this work, the feasibility of using T2rho weighting as an MR contrast mechanism is evaluated. Axial images of a human brain were acquired using a single-slice spin-lock T2rho-weighted pulse sequence and compared to analogous T2-weighted images of the same slice. The contrast between white matter and gray matter in T2rho-weighted images was approximately 40% greater than that from T2-weighted data. These preliminary data suggest that the novel contrast mechanism of T2rho can be used to yield high-contrast T2-like images.
authors.affiliation: Department of Radiology, University of Pennsylvania, Philadelphia 19104-6100, USA. wheaton@seas.upenn.edu
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Wheaton
authors.forename: Arijitt
authors.initials: A
authors.lastname: Borthakur
authors.forename: Matthew T
authors.initials: MT
authors.lastname: Corbo
authors.forename: Gul
authors.initials: G
authors.lastname: Moonis
authors.forename: Elias
authors.initials: E
authors.lastname: Melhem
authors.forename: Ravinder
authors.initials: R
authors.lastname: Reddy
mesh_terms: D000328:Adult; D001931:Brain Mapping; D005240:Feasibility Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male