title: On the diagnosis and management of neurocutaneous syndrome, a toxicity disorder from dental sealants.
abstract: Neurocutaneous syndrome, a newly discovered toxicity disorder, is characterized by neurological sensations, pain, depleted energy, and memory loss as well as itchy cutaneous lesions that may invite various opportunistic infections. Components in the calcium hydroxide dental sealants Dycal, Life and Sealapex have been identified as sources of the observed symptoms. Sulfonamide and neurological toxicity issues are discussed, and three case histories are presented. Additional notes on zinc oxide, Fynal, IRM, and Sultan U/P sealers are also included. Diagnostic and management protocols at the Parasitology Center, Inc., are proposed.
authors.affiliation: Parasitology Center, Inc., Phoenix, Ariz, USA.
authors.forename: Omar M
authors.initials: OM
authors.lastname: Amin
mesh_terms: D000328:Adult; D002126:Calcium Hydroxide / Q000737:chemistry / Q000633:toxicity; D003731:Dental Caries / Q000628:therapy; D003736:Dental Cavity Lining / Q000009:adverse effects* / Q000379:methods; D003737:Dental Cavity Preparation / Q000379:methods; D003764:Dental Materials / Q000737:chemistry / Q000633:toxicity; D003785:Dental Pulp Capping / Q000009:adverse effects* / Q000379:methods; D003793:Dental Restoration, Permanent / Q000009:adverse effects; D005260:Female; D006801:Humans; D007284:Inlays / Q000009:adverse effects; D008903:Minerals / Q000737:chemistry / Q000633:toxicity; D020752:Neurocutaneous Syndromes / Q000139:chemically induced / Q000175:diagnosis* / Q000628:therapy*; D010895:Pit and Fissure Sealants / Q000737:chemistry / Q000627:therapeutic use / Q000633:toxicity*; D012086:Reoperation; D012459:Salicylates / Q000737:chemistry / Q000633:toxicity
chemical_list: D003764:Dental Materials; D008903:Minerals; D010895:Pit and Fissure Sealants; D012459:Salicylates; C055601:Sealapex; C025702:Dycal; C040408:Life (dental material); D002126:Calcium Hydroxide