title: Effects of intralaminar thalamic stimulation on language functions.
abstract: Fifteen neurosurgical subjects, who were undergoing thalamic chronic electrode implants as a treatment for dyskinesia and chronic pain, were evaluated on a series of neurolinguistic functions to determine if the stimulation of the centromedianum nucleus of the thalamus affected language and cognitive processing. Analysis of the data revealed that the stimulation of the left centromedianum nucleus had resulted in a notable facilitatory influence on the processing of language functions; this facilitatory effect was measured in terms of the number of errors produced and the patients' response latency time. The facilitatory effect was also noted to have extended to other language functions. The nature of the facilitation from the stimulation of the left centromedianum nucleus, an extension of the brainstem reticular formation, on language functions is discussed.
authors.affiliation: Speech Pathology and Audiology Department, Marquette University, Milwaukee, WI 53233, USA. subhash.bhatnagar@marquette.edu
authors.forename: Subhash C
authors.initials: SC
authors.lastname: Bhatnagar
authors.forename: George T
authors.initials: GT
authors.lastname: Mandybur
mesh_terms: D000328:Adult; D000368:Aged; D001933:Brain Stem / Q000502:physiology; D003071:Cognition; D020820:Dyskinesias / Q000628:therapy*; D004558:Electric Stimulation / Q000295:instrumentation; D004567:Electrodes, Implanted; D005260:Female; D006801:Humans; D020646:Intralaminar Thalamic Nuclei / Q000502:physiology*; D007802:Language; D008297:Male; D008875:Middle Aged; D011930:Reaction Time; D012154:Reticular Formation / Q000502:physiology; D013238:Stereotaxic Techniques