S-100 protein immunoreactivity in the upper eyelid of the sheep Ovis aries.
The aim of this work was to analyse the distribution pattern of S-100-immunoreactive elements in the upper eyelid of the sheep. This pattern may be of importance regarding the diagnosis and prognosis of eyelid tumours that are linked to deregulation of S-100 gene expression. Thirty upper eyelids taken from 15 adult male Ovis aries were studied by means of the peroxidase-antiperoxidase method for light microscopy. S-100-immunopositive cells were found in the eyelid edge. S-100-immunopositive steams and thinner fibres were found throughout the eyelid. These nerve processes typically were denser around glands, hair follicles and blood vessels. S-100-immunopositive elements may play a role as neuromodulator and also in the development of the vegetative innervation of the epithelium and its derivatives.
Aisa
J
J
Department of Human Anatomy and Histology, School of Medicine, University of Zaragoza, 50.009 Zaragoza, Spain.
Lahoz
M
M
Serrano
P
P
Pérez-Castejón
M C
MC
Junquera
C
C
Martínez-Ciriano
M C
MC
Pes
N
N
Vera-Gil
A
A
D000818:Animals; D001808:Blood Vessels / Q000378:metabolism; D005142:Eyelid Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology; D005143:Eyelids / Q000098:blood supply / Q000294:innervation / Q000378:metabolism*; D005786:Gene Expression Regulation; D018859:Hair Follicle / Q000378:metabolism*; D007150:Immunohistochemistry; D008297:Male; D010525:Peripheral Nerves / Q000378:metabolism*; D009418:S100 Proteins / Q000378:metabolism*; D012756:Sheep
D009418:S100 Proteins