The role of magnetic resonance imaging in diagnosis and management of breast cancer.
A review of the literature on the current applications of breast magnetic resonance imaging (MRI) indications, their rationale and their place in diagnosis and management of breast cancer was given. Contrast-enhanced breast MRI is developing as a valuable adjunct to mammography and sonography. Its high sensitivity for invasive breast cancer establishes its superiority in evaluation of multifocality/multicentricity, tumor response to neoadjuvant chemotherapy, detection of recurrence, and staging. Emerging applications include spectroscopy, usage of new contrast agents, and MRI-guided interventions, including noninvasive treatment of breast cancer. Its potential benefit in screening high-risk women has yet to be established with prospective studies, particularly with regard to false positive results.
Pavic
Dag
D
Department of Radiology, University of North Carolina at Chapel Hill Medical School, CB 7510, 101 Manning Dr., Chapel Hill, NC 27599, USA. Dag_Pavic@med.unc.edu
Koomen
Marcia A
MA
Kuzmiak
Cherie M
CM
Lee
Y H
YH
Pisano
Etta D
ED
D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008207:Lymphatic Metastasis / Q000175:diagnosis / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000295:instrumentation* / Q000379:methods*; D015412:Mastectomy, Segmental; D020360:Neoadjuvant Therapy