[Risk factors of atherosclerosis in end-stage renal disease patients].
Patients with end-stage renal disease have greatly elevated risks of atherosclerotic disease. Vascular calcification in advanced atherosclerosis is a common feature in ESRD patients. Risk factors of atherosclerosis in ESRD patients are coronary risk factors such as hypertension, diabetes and hyperlipidemia and hyperphosphatemia. Bone associated proteins including osteopontin, matrix Gla protein and osteoprotegerin may be involved in the progression of atherosclerosis.
Jono
Shuichi
S
Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
D001161:Arteriosclerosis / Q000209:etiology*; D002135:Calcium-Binding Proteins / Q000502:physiology; D048909:Diabetes Complications; D003920:Diabetes Mellitus; D016326:Extracellular Matrix Proteins / Q000502:physiology; D006023:Glycoproteins / Q000502:physiology; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications; D006973:Hypertension / Q000150:complications; D007676:Kidney Failure, Chronic / Q000150:complications*; D053495:Osteopontin; D053244:Osteoprotegerin; D018160:Receptors, Cytoplasmic and Nuclear / Q000502:physiology; D018124:Receptors, Tumor Necrosis Factor; D012307:Risk Factors; D012795:Sialoglycoproteins / Q000502:physiology; D000097568:Matrix Gla Protein
D002135:Calcium-Binding Proteins; D016326:Extracellular Matrix Proteins; D006023:Glycoproteins; D053495:Osteopontin; D053244:Osteoprotegerin; D018160:Receptors, Cytoplasmic and Nuclear; D018124:Receptors, Tumor Necrosis Factor; D012795:Sialoglycoproteins; D000097568:Matrix Gla Protein; C506895:SPP1 protein, human; C506030:TNFRSF11B protein, human