[Pharmacological correction of memory impairment caused by a complex extremal action in mice with bilateral ligation of common carotid arteries].
Semax and mexidol significantly increase the survival of white mongrel male mice upon bilateral ligation of common carotid arteries. Semax virtually completely prevented retrograde amnesia development in ligated mice under conditions of a complex extremal action (emaciating swim in cold water with simultaneous wheel rotation) and increased the lifetime of these animals in altitude test chamber.
Iasnetsov
V V
VV
Ivanov
Iu V
IuV
D000324:Adrenocorticotropic Hormone / Q000008:administration & dosage / Q000031:analogs & derivatives*; D000648:Amnesia, Retrograde / Q000517:prevention & control*; D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage*; D017536:Carotid Artery, Common; D008026:Ligation; D008297:Male; D051379:Mice; D018697:Nootropic Agents / Q000008:administration & dosage*; D010446:Peptide Fragments / Q000008:administration & dosage*; D010847:Picolines / Q000008:administration & dosage*
D000975:Antioxidants; D018697:Nootropic Agents; D010446:Peptide Fragments; D010847:Picolines; C070020:emoxypine succinate; C048487:ACTH (4-7), Pro-Gly-Pro-; D000324:Adrenocorticotropic Hormone