title: [Investigation of cross-infection of Pseudomonas aeruginosa in an intensive care unit].
abstract: OBJECTIVE
  To investigate the factors responsible for Pseudomonas aeruginosa nosocomial cross-infection in the intensive care unit (ICU) and provide effective measure for the prevention and management.
  
  
  METHODS
  The homology of 7 Pseudomonas aeruginosa strains isolated from the patients in the ICU and the environment was examined by biological, serological, drug-resistance and plasmid analysis.
  
  
  RESULTS
  The results of serological and plasmid analyses had good consistency, which demonstrated that the 7 Pseudomonas aeruginosa strains originated from solution in the oxygen humidifier, with uniform serological and plasmid type, and belonged to the same clone with cross-infection by contact between the patients or nursing staff and the objects in the ICU.
  
  
  CONCLUSIONS
  Serological and plasmid analyses are more practical for identifying the sources of Pseudomonas aeruginosa cross-infection, which can be prevented by strict disinfection of the instrument and supervision of the nursing staff in the ICU.
authors.affiliation: Department of Blood Transfusion, Nanfang Hospital, Southern Medical University, Guangzhou 510315, China. laifucai@fimmu.com
authors.forename: Fu-cai
authors.initials: FC
authors.lastname: Lai
authors.forename: Ying-ming
authors.initials: YM
authors.lastname: Bai
authors.forename: Cheng-hui
authors.initials: CH
authors.lastname: Mu
authors.forename: Dao-bo
authors.initials: DB
authors.lastname: Peng
authors.forename: Hui
authors.initials: H
authors.lastname: Zhao
mesh_terms: D003428:Cross Infection / Q000382:microbiology* / Q000517:prevention & control; D006801:Humans; D007362:Intensive Care Units; D011552:Pseudomonas Infections / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000145:classification / Q000302:isolation & purification*