title: [Interest of sentinel lymph node biopsy for the staging of ductal carcinoma in situ].
abstract: OBJECTIVE
  The aim of this study was to define the interest of sentinel lymph node biopsy (SLNB) for the staging of ductal carcinoma in situ (DCIS) and DCIS with micro-invasion (DCISM) in patients with breast carcinoma.
  
  
  METHODS
  From June 1999 to December 2002 we listed, in a retrospective study, 52 patients treated surgically for a DCIS or a DCISM. All except one had an histology before surgery, and all had SLNB. Intraoperative imprint cytology of the sentinel lymph node (SLN) was performed then there were analysed by staining with hematoxylin-eosin. Patients with positive SLN underwent complete axillary dissection.
  
  
  RESULTS
  It was removed an average of three SLNs by patient (extreme 1 to 6). Metastases in the SLN were detected in four (7,7%) of the 52 patients, including three cases had only micrometastases in the SLN. In the four patients treated with complete axillary dissection, the SLN were the only positives nodes.
  
  
  CONCLUSIONS
  The SLNB for DCIS and DCISM increases the involvement rate of lymph node. Because of the widespread for early detection of breast cancer, it is noted a regular increase in the rate of DCIS. Even if the attitude to be had towards the lymph node metastases in these cases is not yet well defined, and so only 2% of the patients approximately die of this pathology, it is interesting because of increase in absolute value of mortality, to try to improve the prognosis criteria to modify the treatment of this pathology.
authors.affiliation: Service de chirurgie oncologique, institut Paoli-Calmettes, 232 boulevard Sainte-Marguerite, BP 156, 13009 Marseille cedex 9, France. buttarellim@marseille.fnclcc.fr
authors.forename: M
authors.initials: M
authors.lastname: Buttarelli
authors.forename: G
authors.initials: G
authors.lastname: Houvenaeghel
authors.forename: M
authors.initials: M
authors.lastname: Martino
authors.forename: I
authors.initials: I
authors.lastname: Rossi
authors.forename: I
authors.initials: I
authors.lastname: Ronda
authors.forename: F
authors.initials: F
authors.lastname: Ternier
authors.forename: A
authors.initials: A
authors.lastname: Tallet
authors.forename: J
authors.initials: J
authors.lastname: Jacquemier
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology*; D005260:Female; D006801:Humans; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D012189:Retrospective Studies; D021701:Sentinel Lymph Node Biopsy