Acute retinal toxicity from the novel anti-tumor agent, Irofulven.
Melendez
Robert F
RF
Department of Ophthalmology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229-3900, USA.
Harrison
Joseph M
JM
Rowinsky
Eric K
EK
Hammond
Lisa A
LA
Fitzsimmons
Thomas D
TD
D000368:Aged; D018906:Antineoplastic Agents, Alkylating / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D008875:Middle Aged; D012160:Retina / Q000187:drug effects* / Q000503:physiopathology; D012164:Retinal Diseases / Q000139:chemically induced* / Q000503:physiopathology; D012717:Sesquiterpenes / Q000009:adverse effects*; D014794:Visual Fields / Q000187:drug effects
D018906:Antineoplastic Agents, Alkylating; D012717:Sesquiterpenes; C102714:irofulven