Two distinct STLV-1 subtypes infecting Mandrillus sphinx follow the geographic distribution of their hosts.
The mandrill (Mandrillus sphinx) has been shown to be infected with an STLV-1 closely related to HTLV-1. Two distinct STLV-1 subtypes (D and F) infect wild mandrills with high overall prevalence (27.0%) but are different with respect to their phylogenetic relationship and parallel to the mandrills' geographic range. The clustering of these new STLV-1mnd sequences with HTLV-1 subtype D and F suggests first, past simian-to-human transmissions in Central Africa and second, that species barriers are easier to cross over than geographic barriers.
Makuwa
M
M
Laboratoire de Virologie, UGENET, CDP, SEGC-Lopé, Centre International de Recherches Médicales, Franceville, Gabon. mmakuwa@yahoo.com
Souquière
S
S
Clifford
S L
SL
Telfer
P T
PT
Sallé
B
B
Bourry
O
O
Onanga
R
R
Mouinga-Ondeme
A
A
Wickings
E J
EJ
Abernethy
K A
KA
Rouquet
P
P
Simon
F
F
Roques
P
P
D000595:Amino Acid Sequence; D000818:Animals; D006800:Deltaretrovirus Infections / Q000662:veterinary* / Q000821:virology; D005260:Female; D005681:Gabon; D016356:Gene Products, tax / Q000737:chemistry / Q000235:genetics; D008297:Male; D048528:Mandrillus / Q000502:physiology / Q000821:virology*; D008969:Molecular Sequence Data; D008992:Monkey Diseases / Q000821:virology*; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D015303:Simian T-lymphotropic virus 1 / Q000145:classification* / Q000235:genetics / Q000472:pathogenicity
D016356:Gene Products, tax