title: Prevention of intraventricular hemorrhage by indomethacin in male preterm infants.
abstract: Our multicenter Indomethacin Intraventricular Hemorrhage (IVH) Prevention Trial demonstrated a reduction of IVH in preterm infants. Analysis of our cohort by sex showed indomethacin halved the incidence of IVH, eliminated parenchymal hemorrhage, and was associated with higher verbal scores at 3 to 8 years in boys.
authors.affiliation: Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA. Laura.ment@yale.edu
authors.forename: Laura R
authors.initials: LR
authors.lastname: Ment
authors.forename: Betty R
authors.initials: BR
authors.lastname: Vohr
authors.forename: Robert W
authors.initials: RW
authors.lastname: Makuch
authors.forename: Michael
authors.initials: M
authors.lastname: Westerveld
authors.forename: Karol H
authors.initials: KH
authors.lastname: Katz
authors.forename: Karen C
authors.initials: KC
authors.lastname: Schneider
authors.forename: Charles C
authors.initials: CC
authors.lastname: Duncan
authors.forename: Richard
authors.initials: R
authors.lastname: Ehrenkranz
authors.forename: William
authors.initials: W
authors.lastname: Oh
authors.forename: Alistair G S
authors.initials: AG
authors.lastname: Philip
authors.forename: David T
authors.initials: DT
authors.lastname: Scott
authors.forename: Walter C
authors.initials: WC
authors.lastname: Allan
mesh_terms: D002317:Cardiovascular Agents / Q000627:therapeutic use*; D002543:Cerebral Hemorrhage / Q000517:prevention & control*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007213:Indomethacin / Q000627:therapeutic use*; D007231:Infant, Newborn; D007234:Infant, Premature; D019102:Infant, Very Low Birth Weight; D007807:Language Tests; D016015:Logistic Models; D008297:Male; D015337:Multicenter Studies as Topic; D016032:Randomized Controlled Trials as Topic; D012727:Sex Characteristics
chemical_list: D002317:Cardiovascular Agents; D007213:Indomethacin