[Diphenhydramin-overdose: anticholinergic symptoms, EEG-findings in the course and drug treatment of a gerontopsychiatric patient].
In this case-study the case of a 76-year old white male with the diagnosis of beginning dementia and psychotic symptoms, who ingested 200 mg of diphenhydramin in suicidal intention, is presented. After a 3 days period in an internal medicine ward, in which he showed only mild anticholinergic symptoms, the patient was transferred to the psychiatric hospital. Here he showed more severe anticholinergic symptoms, including EEG-changes, for a prolonged period of two weeks time. This case helps to show the relevance of closer observation and EEG-controls in gerontopsychiatric patients even after the ingestion of a comparatively low dose of antihistaminics.
Englert
Isabel
I
Krankenhaus Schloss Werneck. isabel.englert@kh-schloss-werneck.de
D000368:Aged; D001921:Brain / Q000187:drug effects*; D018680:Cholinergic Antagonists / Q000506:poisoning*; D003704:Dementia / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D003866:Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D004155:Diphenhydramine / Q000506:poisoning*; D004359:Drug Therapy, Combination; D004569:Electroencephalography / Q000187:drug effects*; D006634:Histamine H1 Antagonists / Q000506:poisoning*; D006801:Humans; D008140:Lorazepam / Q000627:therapeutic use; D008297:Male; D010259:Paranoid Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D011041:Poisoning / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D018967:Risperidone / Q000627:therapeutic use; D013406:Suicide, Attempted / Q000523:psychology*; D013693:Temazepam / Q000627:therapeutic use
D018680:Cholinergic Antagonists; D006634:Histamine H1 Antagonists; D004155:Diphenhydramine; D013693:Temazepam; D018967:Risperidone; D008140:Lorazepam