Non-neurologic manifestations of tuberous sclerosis complex.
Tuberous sclerosis complex is a heterogeneous genetic disorder affecting multiple organ systems at various points throughout the lifespan. Increasingly, neurologically asymptomatic adults are being diagnosed with tuberous sclerosis complex through renal or pulmonary presentations. Although chiefly recognized for its cerebral manifestations, understanding of the non-neurologic aspects of the disorder has advanced greatly in recent years, and they are reviewed here.
Franz
David Neal
DN
Tuberous Sclerosis Clinic, University of Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. david.franz@chmcc.org
D000328:Adult; D006331:Heart Diseases / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology* / Q000473:pathology; D008171:Lung Diseases / Q000209:etiology* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D012164:Retinal Diseases / Q000209:etiology* / Q000473:pathology; D014076:Tooth Diseases / Q000209:etiology; D014402:Tuberous Sclerosis / Q000150:complications*