Effects of egg yolk proteins on the longitudinal bone growth of adolescent male rats.
Hen egg is a nutritional store for a new life. We examined the effect of egg yolk proteins on longitudinal bone growth in the rat. Protein fractions from egg yolk were tested. Milk protein, casein, was used as a control. The bone growth rate was significantly increased by yolk water-soluble protein (YSP, 100 mg/kg) administration for 5 d. The bone morphogenetic protein-2 immunostaining of growth plate was also increased. Considering the results, YSP can be used as a growth-promoting factor.
Leem
Kang-Hyun
KH
College of Oriental Medicine, Semyung University, Chungbuk, South Korea.
Kim
Myung-Gyou
MG
Kim
Hyun-Mi
HM
Kim
Mujo
M
Lee
Young-Ja
YJ
Kim
Hye Kyung
HK
D000818:Animals; D048588:Benzoxazines; D001846:Bone Development / Q000187:drug effects*; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins / Q000378:metabolism; D001842:Bone and Bones / Q000166:cytology; D002364:Caseins / Q000494:pharmacology; D019902:Chondrocytes / Q000187:drug effects; D004527:Egg Proteins / Q000494:pharmacology*; D008297:Male; D010078:Oxazines; D051381:Rats; D017207:Rats, Sprague-Dawley; D013268:Stimulation, Chemical; D016212:Transforming Growth Factor beta / Q000378:metabolism
D048588:Benzoxazines; C525720:Bmp2 protein, rat; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins; D002364:Caseins; D004527:Egg Proteins; D010078:Oxazines; D016212:Transforming Growth Factor beta; C028911:cresyl violet