Nitric oxide in neurodegenerative diseases.
Nitric oxide (NO) free radical as a major signaling molecule in nervous systems has been shown to have close relationship with neurodegenerative diseases. The results about the relation of NO and neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD) and stroke in recent years are reviewed. Particularly, the results of antioxidants and NO in neurodegenerative disorders from author's own laboratory are included in this paper.
Zhao
Baolu
B
Center of Brain and Cognitive Sciences, Institute of Biophysics, Academia Sinica, Beijing 100101, PR China. zhaobl@sun5.ibp.ac.cn
D000544:Alzheimer Disease / Q000378:metabolism; D000818:Animals; D000975:Antioxidants / Q000378:metabolism / Q000494:pharmacology; D001921:Brain / Q000378:metabolism; D005609:Free Radicals; D006801:Humans; D019636:Neurodegenerative Diseases / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism; D009569:Nitric Oxide / Q000737:chemistry* / Q000378:metabolism; D010300:Parkinson Disease / Q000378:metabolism; D020521:Stroke / Q000473:pathology
D000975:Antioxidants; D005609:Free Radicals; D009569:Nitric Oxide