title: Histiocytic necrotising lymphadenitis (Kikuchi's disease): a rare cause of cervical lymphadenopathy.
abstract: Both Head and Neck Surgeons and General Surgeons are frequently referred patients with cervical lymphadenopathy. An uncommon but important cause is histiocytic necrotising lymphadenitis. This is a benign self-limiting disease that has been confused with malignant lymphomas. Some patients may also experience distressing and debilitating symptoms which can last for months. We describe four cases to illustrate the varied clinical presentation of this disease and present new signs seen in association with it. A remarkable therapeutic response to a short course of oral corticosteroids was observed in one case.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, South Manchester University Hospitals NHS Trust, Manchester, UK. viv959@yahoo.co.uk
authors.forename: V
authors.initials: V
authors.lastname: Kaushik
authors.forename: T H
authors.initials: TH
authors.lastname: Malik
authors.forename: P W
authors.initials: PW
authors.lastname: Bishop
authors.forename: P H
authors.initials: PH
authors.lastname: Jones
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D001707:Biopsy, Needle; D005260:Female; D005500:Follow-Up Studies; D020042:Histiocytic Necrotizing Lymphadenitis / Q000188:drug therapy* / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D007150:Immunohistochemistry; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D018570:Risk Assessment; D012494:Sampling Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones