Colonic neuroendocrine carcinoma in a child.
A 10-year-old boy with congenital immunodeficiency (X-linked agammaglobulinaemia) presented with loss of appetite and weight, right-sided abdominal pain, diarrhoea and low-grade fever. Radiological investigations with barium follow-through, CT, PET and octreotide scans revealed a primary caecal/ascending proximal colonic mass with liver and bony metastases. Urine screen for 5HIAA was positive. Percutaneous liver biopsy confirmed the diagnosis of neuroendocrine carcinoma. The radiological work-up and the usefulness of various imaging modalities in the diagnosis of this rare paediatric tumour are discussed. The PET scan demonstrated the primary tumour and the metastatic locations more vividly than the octreotide scan, which is currently considered to be the most specific imaging modality for neuroendocrine masses.
Sasi
Omai Al
OA
Department of Radiology, MBC#28, King Faisal Specialist Hospital and Research Centre, PO Box 3354, 11211, Riyadh, Saudi Arabia. dr_omaialsasi@hotmail.com
Sathiapalan
Rajeev
R
Rifai
Ayman
A
Tulbah
Asthma Mahmoud Mohamed
AM
Al-Mehaidib
Ali
A
Kofide
Amani
A
Hugosson
Claes
C
D001706:Biopsy; D018278:Carcinoma, Neuroendocrine / Q000000981:diagnostic imaging*; D002648:Child; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005765:Gastrointestinal Agents; D006801:Humans; D007205:Indium Radioisotopes; D008297:Male; D015282:Octreotide; D049268:Positron-Emission Tomography
D005765:Gastrointestinal Agents; D007205:Indium Radioisotopes; D015282:Octreotide