title: Benign mixed tumour of the skin with extensive ossification and marrow formation: a case report.
abstract: Benign mixed tumour of the skin (chondroid syringoma) is an uncommon skin adnexal tumour, usually presenting as a slow growing solitary painless nodule. The morphological appearances are similar to those of a pleomorphic adenoma of the salivary gland. Hair matrix and sebaceous differentiation can be seen in some lesions. Focal ossification is a rare finding. This report presents a case of a similar tumour arising in the cheek of a 43 year old white man, showing extensive ossification. Clinical, radiological, and pathological correlation and diagnosis proved to be difficult preoperatively. Only two cases of a benign mixed tumour with pronounced ossification have been reported so far, both in Japanese patients. This is the first reported case seen in a white man. Awareness of these lesions will avoid potential diagnostic pitfalls.
authors.affiliation: Department of Histopathology, Derriford Hospital, Derriford Road, Plymouth PL6 8DH, UK. rachnaawashti@hotmail.com
authors.forename: R
authors.initials: R
authors.lastname: Awasthi
authors.forename: D
authors.initials: D
authors.lastname: Harmse
authors.forename: D
authors.initials: D
authors.lastname: Courtney
authors.forename: C B A
authors.initials: CB
authors.lastname: Lyons
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology*; D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D006801:Humans; D008297:Male; D009999:Ossification, Heterotopic / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000473:pathology*