title: Concordance correlation in the measurements of time to event.
abstract: The concordance correlation coefficient (CCC), a measure of concordance in ratings from multiple raters, was used to study inter-rater agreement in measurements of time to event, generally not observed with perfect consistency among raters. As a function of the first two moments of rating measures, the CCC can be estimated with data subject to censoring, using a likelihood-based estimation method applied under the assumptions of random censoring and parametric distribution models for the ratings of time to event. A simulation study was conducted for small sample performance under various censoring proportions. The use of the CCC with censored data is illustrated with an example taken from a data set containing data on time to an event with two raters per subject.
authors.affiliation: Department of Biostatistics, New York State Psychiatric Institute & Columbia University, New York, NY 10032, USA. x126@columbia.edu
authors.forename: Xinhua
authors.initials: X
authors.lastname: Liu
authors.forename: Yunling
authors.initials: Y
authors.lastname: Du
authors.forename: Jeanne
authors.initials: J
authors.lastname: Teresi
authors.forename: Deborah S
authors.initials: DS
authors.lastname: Hasin
mesh_terms: D000293:Adolescent; D000328:Adult; D003198:Computer Simulation; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D008137:Longitudinal Studies; D008297:Male; D001523:Mental Disorders / Q000150:complications; D008875:Middle Aged; D015588:Observer Variation; D015203:Reproducibility of Results; D018709:Statistics, Nonparametric; D019966:Substance-Related Disorders / Q000150:complications