title: Functions of the HIV-1 Nef protein.
abstract: The Nef protein of the human immunodeficiency virus is as important for disease progression as it is perplexing in its number of target molecules and functions. In this chapter I will try to give an overview on the numerous functions of HIV from a molecular as well as functional point of view. Due to space restriction and for the sake of clarity I will not describe or list all the effects reported in the literature but rather concentrate on the most important aspects of Nef function.
authors.affiliation: University of Miami, School of Medicine, Department of Microbiology and Immunology, P.O. Box 016960 (R-138), Miami, FL 33101, USA. abaur@med.miami.edu
authors.forename: Andreas
authors.initials: A
authors.lastname: Baur
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000502:physiology; D015693:Gene Products, nef / Q000502:physiology*; D015497:HIV-1 / Q000502:physiology*; D006801:Humans; D015398:Signal Transduction / Q000502:physiology; D054311:nef Gene Products, Human Immunodeficiency Virus
chemical_list: D015693:Gene Products, nef; D054311:nef Gene Products, Human Immunodeficiency Virus