title: Catalytic enantioselective hydrogenation of vinyl bis(boronates).
abstract: Catalytic enantioselective hydrogenation of prochiral vinylmetallic reagents can provide an attractive alternative to hydrometalation and bismetalation of alkenes. In this contribution, the first highly enantioselective hydrogenation of vinyl boronic esters is described. The chiral reduction products are versatile intermediates for chemical synthesis.
authors.affiliation: Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290, USA.
authors.forename: Jeremy B
authors.initials: JB
authors.lastname: Morgan
authors.forename: James P
authors.initials: JP
authors.lastname: Morken
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis*; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D006865:Hydrogenation; D010084:Oxidation-Reduction; D013237:Stereoisomerism; D014753:Vinyl Compounds / Q000737:chemistry*
chemical_list: D000438:Alcohols; D001897:Boronic Acids; D014753:Vinyl Compounds