[Study on the SFE condition for curcumin in Curcuma longa].
OBJECTIVE
To optimize the conditions of supercritical fluid extraction (SFE) for curcumin in Curcuma longa.


METHODS
Optimum extraction conditions were studied by orthogonal tests. The extracts were analyzed by HPLC.


RESULTS
The optimal extraction conditions were pressure 25 MPa, temperature 55 degrees C, static time 4 h, dynamic time 5 h, flow rate of CO2 3.5 L x min(-1), co-solvent ethanol 30% (mL x g(-1)).


CONCLUSIONS
It is feasible to extract curcumin by SFE.
Su
Shu-lan
SL
Department of Pharmaceutical Engineering of Jiangsu University, Zhenjian 212013 China. lyhssl@ujs.edu.cn
Wu
Qi-nan
QN
Ouyang
Zhen
Z
Wu
De-kang
DK
Chen
Jun
J
D002245:Carbon Dioxide; D025924:Chromatography, Supercritical Fluid / Q000379:methods*; D030024:Curcuma / Q000737:chemistry*; D003474:Curcumin / Q000032:analysis / Q000302:isolation & purification*; D000431:Ethanol; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011312:Pressure; D013696:Temperature; D013997:Time Factors
D002245:Carbon Dioxide; D000431:Ethanol; D003474:Curcumin