title: Brain perfusion territory imaging applying oblique-plane arterial spin labeling with a standard send/receive head coil.
abstract: A new method for the selective spin labeling of left- or right-sided supplying arteries of the brain without the need for additional RF coils is demonstrated. A clinical 1.5 T scanner was used. The spatial selectivity of the labeling process is based on the limited coverage of the excitation field of a standard send/receive head coil together with an oblique positioning of the labeling plane. A computer simulation was used to optimize key labeling parameters under the condition of laminar flow. The validity of the computer model results was confirmed by MRI measurements with a flow model. For human studies, a double-inversion continuous arterial spin labeling (CASL) sequence was modified to allow for arbitrary positioning of the labeling plane. The obtained perfusion-weighted images showed a clear delineation of the perfusion territories of the selected arteries in the anterior circulation of the brain and good gray/white matter contrast.
authors.affiliation: Section of Neuroradiology, Christian-Albrechts-Universität, Kiel, Germany. wernerr@nch.uni-kiel.de
authors.forename: Richard
authors.initials: R
authors.lastname: Werner
authors.forename: Karsten
authors.initials: K
authors.lastname: Alfke
authors.forename: Tobias
authors.initials: T
authors.lastname: Schaeffter
authors.forename: Arya
authors.initials: A
authors.lastname: Nabavi
authors.forename: H Maximilian
authors.initials: HM
authors.lastname: Mehdorn
authors.forename: Olav
authors.initials: O
authors.lastname: Jansen
mesh_terms: D001931:Brain Mapping; D002560:Cerebrovascular Circulation; D003198:Computer Simulation; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D019047:Phantoms, Imaging; D013113:Spin Labels
chemical_list: D013113:Spin Labels