title: Direct access to ketones from aldehydes via rhodium-catalyzed cross-coupling reaction with potassium trifluoro(organo)borates.
abstract: A direct cross-coupling reaction of aromatic aldehydes with potassium trifluoro(organo)borates afforded ketones in high yields and under mild conditions in the presence of a rhodium catalyst and acetone. This new reaction, involving a formal aldehyde C-H bond activation, is believed to proceed via a Heck-type mechanism followed by hydride transfer to acetone.
authors.affiliation: Laboratoire de Synthèse Sélective Organique (UMR 7573, CNRS), Ecole Nationale Supérieure de Chimie de Paris, 11 rue P&M Curie, 75231 Paris Cedex 05, France.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Pucheault
authors.forename: Sylvain
authors.initials: S
authors.lastname: Darses
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Genet