title: Tricalcium phosphate granules or rigid wedge preforms in open wedge high tibial osteotomy: a radiological study with a new evaluation system.
abstract: The capacity of two forms of porous beta-tricalcium phosphate bone substitutes (TCP) to promote bone healing in open wedge high tibial osteotomy (OWHTO) was studied. We reviewed the X-rays of 27 osteotomies, with either TCP wedges or TCP granules as filling material, to compare the bone healing rates and bone remodelling, at specific postoperative intervals. A new radiologic rating system for OWHTO was created and tested for clinical applicability. All osteotomies healed uneventfully and complete resorption of TCP was demonstrated at 1 year postoperative in 85% (n = 23) of the procedures. In 44% (n = 10) of these 23 procedures, the osteotomy site was no longer visible. No difference in bone healing rate and bone remodelling was found when comparing the use of granules to a wedge, and no adverse effects of TCP were observed. The good inter- (k = 0.7) and intraobserver (k = 0.6) reliability of the new radiologic rating system enables clinical use. Good bone healing was found in OWHTO with both wedges and granules of TCP.
authors.affiliation: Department of Orthopaedic Surgery, Limb Deformity Reconstruction Unit, Sint Maartenskliniek, Nijmegen, The Netherlands.
authors.forename: Wouter L W
authors.initials: WL
authors.lastname: van Hemert
authors.forename: Karel
authors.initials: K
authors.lastname: Willems
authors.forename: Patricia G
authors.initials: PG
authors.lastname: Anderson
authors.forename: Ronald J
authors.initials: RJ
authors.lastname: van Heerwaarden
authors.forename: Ate B
authors.initials: AB
authors.lastname: Wymenga
mesh_terms: D000328:Adult; D001860:Bone Plates; D001861:Bone Regeneration / Q000187:drug effects; D018786:Bone Substitutes / Q000627:therapeutic use*; D002130:Calcium Phosphates / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging* / Q000601:surgery; D008297:Male; D020370:Osteoarthritis, Knee / Q000000981:diagnostic imaging / Q000601:surgery; D010027:Osteotomy / Q000379:methods*; D011859:Radiography; D015203:Reproducibility of Results; D013977:Tibia / Q000000981:diagnostic imaging / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D018786:Bone Substitutes; D002130:Calcium Phosphates; C018392:tricalcium phosphate