Hodgkin's disease-related central nervous system angiopathy presenting as reversible posterior leukoencephalopathy.
Reversible posterior leukoencephalopathy syndrome (RPLS) is a clinical syndrome characterized by headache, conscious disturbance, seizure, and cortical visual loss with neuroimaging finding of edema in the posterior regions of the brain, with a reversible course (1). The precise pathomechanism of RPLS is not understood. However, association with uncontrolled hypertension, renal failure, eclampsia, or immunosuppressive agents has been implicated (1). We describe herein a case of Hodgkin's disease (HD)-related central nervous system (CNS) angiitis with neuroimaging finding suggestive of RPLS. The pathophysiology of RPLS in cases with CNS angiitis is discussed.
Miyazaki
Yusei
Y
Department of Neurology, Sapporo City General Hospital.
Tajima
Yasutaka
Y
Sudo
Kazumasa
K
Matsumoto
Akihisa
A
Tashiro
Jun
J
Kikuchi
Seiji
S
Sasaki
Hidenao
H
Tashiro
Kunio
K
D000328:Adult; D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000209:etiology*; D002533:Cerebral Angiography; D003937:Diagnosis, Differential; D005260:Female; D005334:Fever / Q000209:etiology; D006261:Headache / Q000209:etiology; D006689:Hodgkin Disease / Q000150:complications*; D006801:Humans; D006973:Hypertension / Q000150:complications; D007674:Kidney Diseases / Q000150:complications; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed; D020293:Vasculitis, Central Nervous System / Q000150:complications* / Q000175:diagnosis