[Microdamage and bone quality].
Fatigue occurs in every material under repetitive loading. Because bone is also being loaded under physiological condition, fatigue also occurs in bone and it is observed as microdamages under light microscope. However, in vivo bone is different from that ex-vivo. It is strongly suggests that in vivo microdamage is repaired by bone remodeling. Once generation and repair of microdamage is imbalanced, microdamage accumulates in bone and causes fatigue fracture.
Mori
Satoshi
S
Department of Orthopedic Surgery Faculty of Medicine, Kagawa University.
D000368:Aged; D000369:Aged, 80 and over; D001842:Bone and Bones / Q000473:pathology / Q000502:physiology*; D006801:Humans; D016474:Weight-Bearing