Population genetic studies of the pancreatic amylase (AMY2, E.C. 3.2.1.1) in Bulgaria.
The pancreatic amylase (AMY2, E.C. 3.2.1.1) polymorphism has been studied in 2346 individuals from south-central and south-eastern Bulgaria. The allele frequencies have been determined as AMY2*1 = 0.9520 and AMY2*2 = 0.0480. The neighbor joining tree of seven subpopulations revealed only small genetic distances. Compared with other populations, the Bulgarian sample clustered with samples from Romania, Hungary, Germany and Switzerland, with larger distances to Albania, Greece and Macedonia.
Baltova
Sofia
S
Department of Anatomy and Physiology of Man, Biological Faculty, University of Plovdiv, Plovdiv, Bulgaria. bsofi@abv.bg
Scheil
Hans-Georg
HG
D000328:Adult; D002031:Bulgaria; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D006801:Humans; D007527:Isoenzymes / Q000235:genetics; D008297:Male; D008565:Membrane Proteins / Q000235:genetics*; D055292:Pancreatic alpha-Amylases; D010641:Phenotype; D011110:Polymorphism, Genetic; D000516:alpha-Amylases
D005819:Genetic Markers; D007527:Isoenzymes; D008565:Membrane Proteins; C513534:AMY2A protein, human; C513535:AMY2B protein, human; D055292:Pancreatic alpha-Amylases; D000516:alpha-Amylases