Content of the HMG-17 chromosomal protein in porcine tissues.
HMG-17 proteins are nucleosomal proteins, implicated in control of chromatin structure and transcription, in a way that has not yet been fully understood. In this report, quantification of HMG-17 in porcine tissues was performed, by ELISA, using previously produced and characterized specific rabbit anti-HMG-17 antibodies. Our results showed high levels of HMG-17 compared to the DNA and H1 content of the tissues (on the contrary to previous reports), and more specifically that there were 1.7 molecules of HMG-17 per molecule of histone H1.
Boumba
Vassiliki A
VA
Laboratory of Biological Chemistry, Greece.
Seferiadis
Konstantin
K
Vougiouklakis
Theodore
T
D000818:Animals; D002875:Chromosomes / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D024242:HMGN2 Protein / Q000032:analysis* / Q000235:genetics / Q000378:metabolism; D007124:Immunoenzyme Techniques / Q000379:methods*; D013552:Swine / Q000235:genetics / Q000378:metabolism
D024242:HMGN2 Protein