title: The influence of superficial venous surgery and compression on incompetent calf perforators in chronic venous leg ulceration.
abstract: OBJECTIVE
  Previous studies have suggested that perforating vein incompetence is reduced by surgery to superficial veins. This study analysed the effect in a randomised clinical trial.
  
  
  METHODS
  Retrospective analysis of duplex data.
  
  
  METHODS
  Patients in this study were part of the ESCHAR randomised controlled trial. All patients had chronic venous leg ulceration with superficial venous reflux. Patients were treated with compression bandaging alone or compression plus superficial venous surgery. Legs were assessed using colour venous duplex prior to treatment and at 3 and 12 months.
  
  
  RESULTS
  Of 500 patients recruited to the ESCHAR trial, 261 were included in this study. One hundred and forty six of 261 legs were treated with compression alone and 115/261 underwent compression and superficial venous surgery. In the compression group, more legs had incompetent perforators at 12 months (77/131) compared to baseline (61/146, p =0.010, Wilcoxon Signed Ranks test for paired data in 131 legs). Following surgery, significantly fewer legs had incompetent calf perforators (59/115 vs 44/104 at 12 months, p =0.001, Wilcoxon Signed Ranks test for paired data in 104 legs). In addition, significantly fewer legs in the compression and surgery group developed new perforator incompetence in comparison to the group treated with compression alone (12/104 vs 36/131, p =0.003, Chi-Squared test).
  
  
  CONCLUSIONS
  Surgical correction of superficial reflux may abolish incompetence in some calf perforators and offer protection against developing new perforator incompetence.
authors.affiliation: Department of Vascular Surgery, Cheltenham General Hospital, GL53 7AN Gloucestershire, UK.
authors.forename: M S
authors.initials: MS
authors.lastname: Gohel
authors.forename: J R
authors.initials: JR
authors.lastname: Barwell
authors.forename: C
authors.initials: C
authors.lastname: Wakely
authors.forename: J
authors.initials: J
authors.lastname: Minor
authors.forename: K
authors.initials: K
authors.lastname: Harvey
authors.forename: J J
authors.initials: JJ
authors.lastname: Earnshaw
authors.forename: B P
authors.initials: BP
authors.lastname: Heather
authors.forename: M R
authors.initials: MR
authors.lastname: Whyman
authors.forename: K R
authors.initials: KR
authors.lastname: Poskitt
mesh_terms: D001458:Bandages; D002908:Chronic Disease; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D012189:Retrospective Studies; D016896:Treatment Outcome; D018615:Ultrasonography, Doppler, Color; D014647:Varicose Ulcer / Q000209:etiology / Q000628:therapy*; D014656:Vascular Surgical Procedures; D014680:Veins / Q000601:surgery*; D014689:Venous Insufficiency / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*