Excess of Pappenheimer bodies (siderocytes) in two splenectomized siblings with congenital dyserythropoietic anemia--type II (CDA-II) and iron overload.
In two splenectomized siblings with congenital dyserythropoietic anemia type-II (CDA-II) and iron overload excess of Pappenheimer bodies reaching 46.4% and 15.9% respectively was found. Cause, significance and differential diagnosis of this finding were discussed.
Chrobák
Ladislav
L
Charles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové: 2nd Department of Medicine, Division of Clinical Hematology. ladislavchrobak@seznam.cz
Matysová
Jindriska
J
D000328:Adult; D000742:Anemia, Dyserythropoietic, Congenital / Q000097:blood* / Q000150:complications / Q000235:genetics / Q000601:surgery; D002675:Child, Preschool; D004912:Erythrocytes / Q000648:ultrastructure*; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D019190:Iron Overload / Q000209:etiology*; D013156:Splenectomy