Prenylated benzophenones and xanthones from Hypericum scabrum.
Two new polyprenylated benzophenones, a new polyprenylated phloroglucinol, and six new xanthone derivatives were isolated from the aerial parts of the Uzbekistan medicinal plant Hypericum scabrum. Their structures were elucidated on the basis of spectroscopic evidence. The isolated compounds showed moderate cytotoxicity for human tumor cells.
Tanaka
Naonobu
N
Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan.
Takaishi
Yoshihisa
Y
Shikishima
Yasuhiro
Y
Nakanishi
Yuka
Y
Bastow
Kenneth
K
Lee
Kuo-Hsiung
KH
Honda
Gisho
G
Ito
Michiho
M
Takeda
Yoshio
Y
Kodzhimatov
Olimjon K
OK
Ashurmetov
Ozodbek
O
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001577:Benzophenones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D020902:Hypericum / Q000737:chemistry*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D014407:Tumor Cells, Cultured; D014610:Uzbekistan; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000972:Antineoplastic Agents, Phytogenic; D001577:Benzophenones; D044004:Xanthones