title: The PedsQL Multidimensional Fatigue Scale in pediatric rheumatology: reliability and validity.
abstract: OBJECTIVE
  . The PedsQL (Pediatric Quality of Life Inventory) is a modular instrument designed to measure health related quality of life (HRQOL) in children and adolescents ages 2-18 years. The recently developed 18-item PedsQL Multidimensional Fatigue Scale was designed to measure fatigue in pediatric patients and comprises the General Fatigue Scale (6 items), Sleep/Rest Fatigue Scale (6 items), and Cognitive Fatigue Scale (6 items). The PedsQL 4.0 Generic Core Scales were developed as the generic core measure to be integrated with the PedsQL Disease-Specific Modules. The PedsQL 3.0 Rheumatology Module was designed to measure pediatric rheumatology-specific HRQOL. Methods. The PedsQL Multidimensional Fatigue Scale, Generic Core Scales, and Rheumatology Module were administered to 163 children and 154 parents (183 families accrued overall) recruited from a pediatric rheumatology clinic. Results. Internal consistency reliability for the PedsQL Multidimensional Fatigue Scale Total Score (a = 0.95 child, 0.95 parent report), General Fatigue Scale (a = 0.93 child, 0.92 parent), Sleep/Rest Fatigue Scale (a = 0.88 child, 0.90 parent), and Cognitive Fatigue Scale (a = 0.93 child, 0.96 parent) were excellent for group and individual comparisons. The validity of the PedsQL Multidimensional Fatigue Scale was confirmed through hypothesized intercorrelations with dimensions of generic and rheumatology-specific HRQOL. The PedsQL Multidimensional Fatigue Scale distinguished between healthy children and children with rheumatic diseases as a group, and was associated with greater disease severity. Children with fibromyalgia manifested greater fatigue than children with other rheumatic diseases.
  
  
  CONCLUSIONS
  The results confirm the initial reliability and validity of the PedsQL Multidimensional Fatigue Scale in pediatric rheumatology.
authors.affiliation: Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, 3137 TAMU, College Station, TX 77843-3137, USA. jvarni@archone.tamu.edu
authors.forename: James W
authors.initials: JW
authors.lastname: Varni
authors.forename: Tasha M
authors.initials: TM
authors.lastname: Burwinkle
authors.forename: Ilona S
authors.initials: IS
authors.lastname: Szer
mesh_terms: D000203:Activities of Daily Living; D000293:Adolescent; D017677:Age Distribution; D001171:Arthritis, Juvenile / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D005221:Fatigue / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D015994:Incidence; D008297:Male; D010372:Pediatrics / Q000592:standards; D011336:Probability; D015203:Reproducibility of Results; D012219:Rheumatology / Q000592:standards; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D017678:Sex Distribution