title: Meta-analysis of randomized controlled trials on hydrocolloid occlusive dressing versus conventional gauze dressing in the healing of chronic wounds.
abstract: Chronic wound management is a difficult area in surgical practice. A wide range of dressings have been recommended for the management of chronic wounds. The present meta-analysis was undertaken to determine the effectiveness of hydrocolloid dressing (HCD) in the healing of chronic wounds compared with conventional gauze dressing. All available controlled clinical trials published before December 2001 that compared HCD to conventional gauze dressing in the healing of chronic wounds were systematically reviewed. We identified and analysed 12 randomized trials (11 published; 1 unpublished) comprising 693 patients with 819 ulcers. The overall odds ratio under the fixed effect model was 1.72, that is, 72% more ulcers healed completely with HCD than with conventional gauze dressing. This result was both clinically and statistically significant.
authors.affiliation: Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Aparajita
authors.initials: A
authors.lastname: Singh
authors.forename: Sajal
authors.initials: S
authors.lastname: Halder
authors.forename: Geetha R
authors.initials: GR
authors.lastname: Menon
authors.forename: Sunil
authors.initials: S
authors.lastname: Chumber
authors.forename: Mahesh Chandra
authors.initials: MC
authors.lastname: Misra
authors.forename: Lalit Kumar
authors.initials: LK
authors.lastname: Sharma
authors.forename: Anurag
authors.initials: A
authors.lastname: Srivastava
mesh_terms: D001458:Bandages; D003102:Colloids; D003362:Cost-Benefit Analysis; D006801:Humans; D009779:Occlusive Dressings; D016017:Odds Ratio; D016032:Randomized Controlled Trials as Topic; D012306:Risk; D014945:Wound Healing
chemical_list: D003102:Colloids