[Influences of second generation antipsychotics on the course of schizophrenia].
Although there were multiple initiatives to modify course and outcome of schizophrenia by optimizing present psychopharmacologic strategies many unsolved problems still exist. There is no doubt that first generation antipsychotics reduce positive symptoms of psychosis but the impact on negative symptoms or disturbances of affect or cognition remains very poor. In contrast second generation antipsychotics show significantly a better tolerability, especially less extrapyramidal side effects. However, they may initiate strong individual side effects. This article reflects advantages and disadvantages of modern antipsychotics on the course of schizophrenia.
Messer
Thomas
T
Bezirkskrankenhaus Augsburg. t.messer@bkh-augsburg.de
D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D004409:Dyskinesia, Drug-Induced / Q000209:etiology; D006801:Humans; D012559:Schizophrenia / Q000188:drug therapy*; D012565:Schizophrenic Psychology; D016896:Treatment Outcome
D014150:Antipsychotic Agents