title: Intramedullary spinal cord metastasis in breast cancer: clinical features, diagnosis, and therapeutic consideration.
abstract: Intramedullary spinal cord metastases (ISCMs) are very rare, but can cause devastating complications from underlying breast cancer. We report the case of a woman with known metastatic breast cancer and progressive neurologic deterioration caused by an ISCM. The epidemiology, pathogenesis, clinical presentation, diagnostic considerations, and therapeutic options are discussed.
authors.affiliation: Department of Medicine, Hematology Oncology Division, University of Florida Health Science Center, 653-1 West 8th St., Jacksonville, FL 32209-6511, USA. augusto.villegas@jax.ufl.edu
authors.forename: Augusto E
authors.initials: AE
authors.lastname: Villegas
authors.forename: Troy H
authors.initials: TH
authors.lastname: Guthrie
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000556:secondary / Q000628:therapy; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009362:Neoplasm Metastasis; D013120:Spinal Cord Neoplasms / Q000175:diagnosis* / Q000556:secondary / Q000628:therapy; D013904:Thoracic Vertebrae