title: [A new crystal form of the Fab fragment of a monoclonal antibody to human interleukin-2: the three-dimensional structure at 2.7 A resolution].
abstract: The three-dimensional structure of the antigen-binding fragment of a monoclonal antibody to human interleukin-2 in a new crystal form (space group P2(1)2(1)2(1); unit cell parameters: a = 42.82, b = 90.68, and c = 139.82 A) was determined by the X-ray molecular replacement method at the resolution of 2.7 A. The protein folding and the stereochemistry of its antigen-binding site were comparatively analyzed. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2004, vol. 30, no. 5; see also http: // www.maik.ru.
authors.forename: V Z
authors.initials: VZ
authors.lastname: Pletnev
authors.forename: E A
authors.initials: EA
authors.lastname: Goriacheva
authors.forename: I N
authors.initials: IN
authors.lastname: Tsygannik
authors.forename: V A
authors.initials: VA
authors.lastname: Nesmeianov
authors.forename: S V
authors.initials: SV
authors.lastname: Pletnev
authors.forename: W
authors.initials: W
authors.lastname: Pangborn
authors.forename: W
authors.initials: W
authors.lastname: Daux
mesh_terms: D000911:Antibodies, Monoclonal / Q000737:chemistry* / Q000276:immunology; D000941:Antigens / Q000378:metabolism; D018360:Crystallography, X-Ray; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000737:chemistry*; D007376:Interleukin-2 / Q000276:immunology*; D008958:Models, Molecular; D011487:Protein Conformation; D014867:Water
chemical_list: D000911:Antibodies, Monoclonal; D000941:Antigens; D007140:Immunoglobulin Fab Fragments; D007376:Interleukin-2; D014867:Water