title: Phosphorylation of nucleotide molecules in hydrothermal environments.
abstract: Phosphorylation of AMP into ADP and ATP, that can outrun their hydrolysis, was made possible in a simulated hydrothermal environment when trimetaphosphate was used as the phosphate source. The best yields of phosphorylated products were obtained when the reaction fluids whose temperature was set at about 100 degrees centigrade was injected into the cold environment maintained at 0 degree in a recycling manner. Hydrothermal environments in the primitive ocean could also have served as prebiotic sites for phosphorylation, among others.
authors.affiliation: Department of BioEngineering, Nagaoka University of Technology, Nagaoka 940-2188, Japan.
authors.forename: Keita
authors.initials: K
authors.lastname: Ozawa
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nemoto
authors.forename: Ei-ichi
authors.initials: E
authors.lastname: Imai
authors.forename: Hajime
authors.initials: H
authors.lastname: Honda
authors.forename: Kuniyuki
authors.initials: K
authors.lastname: Hatori
authors.forename: Koichiro
authors.initials: K
authors.lastname: Matsuno
mesh_terms: D000227:Adenine Nucleotides / Q000737:chemistry*; D003080:Cold Temperature; D004777:Environment; D006358:Hot Temperature; D009792:Oceans and Seas; D010710:Phosphates / Q000737:chemistry*; D010766:Phosphorylation
chemical_list: D000227:Adenine Nucleotides; D010710:Phosphates