Design of a data model for developing laboratory information management and analysis systems for protein production.
Data management has emerged as one of the central issues in the high-throughput processes of taking a protein target sequence through to a protein sample. To simplify this task, and following extensive consultation with the international structural genomics community, we describe here a model of the data related to protein production. The model is suitable for both large and small facilities for use in tracking samples, experiments, and results through the many procedures involved. The model is described in Unified Modeling Language (UML). In addition, we present relational database schemas derived from the UML. These relational schemas are already in use in a number of data management projects.
Pajon
Anne
A
EMBL Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
Ionides
John
J
Diprose
Jon
J
Fillon
Joël
J
Fogh
Rasmus
R
Ashton
Alun W
AW
Berman
Helen
H
Boucher
Wayne
W
Cygler
Miroslaw
M
Deleury
Emeline
E
Esnouf
Robert
R
Janin
Joël
J
Kim
Rosalind
R
Krimm
Isabelle
I
Lawson
Catherine L
CL
Oeuillet
Eric
E
Poupon
Anne
A
Raymond
Stéphane
S
Stevens
Tim
T
van Tilbeurgh
Herman
H
Westbrook
John
J
Wood
Peter
P
Ulrich
Eldon
E
Vranken
Wim
W
Xueli
Li
L
Laue
Ernest
E
Stuart
David I
DI
Henrick
Kim
K
D000465:Algorithms; D000595:Amino Acid Sequence; D003627:Data Interpretation, Statistical; D030562:Databases, Protein; D023281:Genomics / Q000379:methods*; D020407:Internet; D008954:Models, Biological; D011381:Programming Languages; D015202:Protein Engineering / Q000379:methods*; D011506:Proteins / Q000737:chemistry*; D040901:Proteomics / Q000379:methods*; D012106:Research; D012984:Software; D012985:Software Design; D049490:Systems Biology; D017432:Unified Medical Language System
D011506:Proteins