title: Reconstruction of the mandible using preshaped 2.3 mm titanium plates, autogenous particulate cortico-cancellous bone grafts and platelet rich plasma: a report on eight patients.
abstract: The results are presented of eight patients who had partial mandibulectomies for malignant tumours and were secondarily reconstructed with pre-shaped 2.3 mm titanium plates, autogenous particulate cortico-cancellous bone grafts and platelet rich plasma. Healing was uneventful in all cases and when prosthodontically needed, implants were inserted after approximately 6 months, whilst biopsies were taken. The histology showed bone remodelling in six cases, whilst in one case after 6 months the bone was largely replaced by abundant fibrous tissue. In this case the implants were lost after 9 months. In one case a new carcinoma developed after 6 months with subsequent death of the patient. Thus, in six patients adequate results were achieved with adequate functional and aesthetic outcome, given the poor conditions of the surrounding tissues. This method provides three-dimensional reconstruction with sufficient bone height and volume to facilitate prosthodontic treatment.
authors.affiliation: Department of Oral and Maxillofacial Surgery, University Medical Center Nijmegen, Nijmegen, The Netherlands. m.merkx@kc.umcn.nl
authors.forename: M A W
authors.initials: MA
authors.lastname: Merkx
authors.forename: J P M
authors.initials: JP
authors.lastname: Fennis
authors.forename: C M
authors.initials: CM
authors.lastname: Verhagen
authors.forename: P J W
authors.initials: PJ
authors.lastname: Stoelinga
mesh_terms: D000368:Aged; D001672:Biocompatible Materials; D001860:Bone Plates; D016723:Bone Remodeling / Q000502:physiology; D016025:Bone Transplantation; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D015921:Dental Implants; D019232:Dental Restoration Failure; D004955:Esthetics, Dental; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008334:Mandible / Q000601:surgery*; D008339:Mandibular Neoplasms / Q000601:surgery; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D017713:Platelet Transfusion; D019651:Plastic Surgery Procedures; D014025:Titanium; D014182:Transplantation, Autologous; D014945:Wound Healing / Q000502:physiology
chemical_list: D001672:Biocompatible Materials; D015921:Dental Implants; D014025:Titanium