title: Pediatric Vision Screener 1: instrument design and operation.
abstract: We develop the Pediatric Vision Screener (PVS) to automatically detect ocular misalignment (strabismus) and defocus in human subjects. The PVS utilizes binocular retinal birefringence scanning to determine when both eyes are aligned, with a theoretical accuracy of <1 deg. The device employs an autoconjugate, bull's-eye detector-based system to detect focus. The focus and alignment pathways are separated by both wavelength and data acquisition timing. Binocular focus and alignment are detected in rapid alternating sequence, measuring both parameters in both eyes in <0.5 sec. In this work, the theory and design of the PVS are described in detail. With objective, automated measurement of both alignment and focus, the PVS represents a new approach to screening children for treatable eye disease such as amblyopia.
authors.affiliation: Harvard Medical School, Children's Hospital Boston, Department of Ophthalmology, 300 Longwood Avenue, Boston, Massachusetts 02115, USA. david.hunter@childrens.harvard.edu
authors.forename: David G
authors.initials: DG
authors.lastname: Hunter
authors.forename: Deborah S
authors.initials: DS
authors.lastname: Nassif
authors.forename: Nadya V
authors.initials: NV
authors.lastname: Piskun
authors.forename: Robert
authors.initials: R
authors.lastname: Winsor
authors.forename: Boris I
authors.initials: BI
authors.lastname: Gramatikov
authors.forename: David L
authors.initials: DL
authors.lastname: Guyton
mesh_terms: D000328:Adult; D000550:Amblyopia / Q000175:diagnosis* / Q000209:etiology; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D055095:Optics and Photonics / Q000295:instrumentation*; D010372:Pediatrics / Q000295:instrumentation* / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013285:Strabismus / Q000150:complications / Q000175:diagnosis*; D014584:User-Computer Interface; D014787:Vision Tests / Q000295:instrumentation* / Q000379:methods