[Acute generalised exanthematous pustolosis in a 2-year-old girl following treatment with amoxicillin].
A two-year-old girl had had fever for one week, and since the previous day general malaise, cutaneous pustolosis with swollen hands and feet. The skin condition had developed three days after the start of amoxicillin therapy. Laboratory tests at the time of admission indicated an infection. The diagnosis was 'acute generalised exanthematous pustulosis' (AGEP). During treatment with a soothing lotion, lasting one week, the patient improved and the skin condition disappeared. AGEP is characterised by acute onset of a pustular eruption in association with fever. It is usually seen after the use of drugs. This is an uncommon disease in children.
van der Meulen
M
M
Reinier de Graaf Groep, afd. Kindergeneeskunde, Reinier de Graafweg 3-11, 2625 AD Delft. meulen@rdgg.nl
van Veen
L
L
van der Lely
N
N
D000658:Amoxicillin / Q000009:adverse effects* / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002675:Child, Preschool; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology*; D005076:Exanthema / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D006801:Humans; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000175:diagnosis
D000900:Anti-Bacterial Agents; D000658:Amoxicillin