title: Esophageal papillomatosis complicated by squamous cell carcinoma in situ.
abstract: We present a case of esophageal papillomatosis with underlying squamous cell carcinoma in situ. An esophageal lesion resected from a 74-year-old woman demonstrated histological findings characteristic of squamous cell papilloma (fibrovascular core and numerous finger-like projections covered with hyperplastic squamous epithelium) and severe dysplasia characteristic of squamous cell carcinoma. The relation of squamous papilloma and squamous cell carcinoma is discussed. It is suggested that esophageal squamous cell papilloma is a premalignant lesion.
authors.affiliation: Department of Surgery, Creighton University School of Medicine, Omaha, Nebraska 68131, USA.
authors.forename: J
authors.initials: J
authors.lastname: Reynoso
authors.forename: R E
authors.initials: RE
authors.lastname: Davis
authors.forename: W W
authors.initials: WW
authors.lastname: Daniels
authors.forename: Z T
authors.initials: ZT
authors.lastname: Awad
authors.forename: Z
authors.initials: Z
authors.lastname: Gatalica
authors.forename: C J
authors.initials: CJ
authors.lastname: Filipi
mesh_terms: D000368:Aged; D001706:Biopsy; D002278:Carcinoma in Situ / Q000175:diagnosis* / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D004724:Endoscopy; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D010212:Papilloma / Q000175:diagnosis* / Q000473:pathology; D011230:Precancerous Conditions / Q000175:diagnosis* / Q000473:pathology