title: [PPARgamma and bone metabolism].
abstract: PPARgamma is a ligand-dependent nuclear receptor and regulates adipogenesis and associates with diabetes, obesity. Recently, relationship between PPARgamma and bone metabolism was investigated. Here, we report the molecular mechanism of PPARgamma transcriptional activity and the suppression of PPARgamma activity by cytokines in bone marrow-derived mesenchymal stem cells.
authors.affiliation: The Institute of Molecular and Cellular Biosciences, The University of Tokyo, Tokyo, Japan.
authors.forename: Ichiro
authors.initials: I
authors.lastname: Takada
authors.forename: Shigeaki
authors.initials: S
authors.lastname: Kato
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000378:metabolism*; D016207:Cytokines / Q000502:physiology; D006801:Humans; D051379:Mice; D047495:PPAR gamma / Q000235:genetics / Q000502:physiology*; D015533:Transcriptional Activation / Q000502:physiology
chemical_list: D016207:Cytokines; D047495:PPAR gamma