title: [Off-pump endovascular treatment of aortic arch aneurysms].
abstract: BACKGROUND
  Traditional repair of aortic arch aneurysms requires cardiopulmonary bypass, hypothermia and circulatory arrest. Endovascular repair is an attractive, less invasive alternative that may change our therapeutic approach. The aim of this study was to review our clinical experience with endovascular treatment of aortic arch aneurysms and to address the new problems in this area.
  
  
  METHODS
  In the last 5 years, we treated 21 patients for aortic arch pathology with an "off-pump" endovascular repair (18 men, 3 women, mean age 71.4 +/- 7.2 years). We used 26 stent grafts (5 Gore Excluder TAG, 3 Endomed Endofit, 6 Medtronic Talent, 12 Cook Zenith TX1) with a mean of 1.2 graft/patient. Proximal fixation of endograft was achieved by means of aortic "de-branching" in 11 cases. In 10 cases the left subclavian artery was intentionally covered without revascularization. Follow-up included clinical examination, chest X-ray and computed tomography at discharge and at 6-month intervals thereafter.
  
  
  RESULTS
  Technical success was 85% (18/21). There was one in-hospital death (4.7%) due to endograft migration. We observed 2 cases of type I endoleak (9.5%). One surgical conversion was performed 2 weeks after the procedure, because of total collapse of the stent graft with rupture of three stents. No complications related to the coverage of the left subclavian artery were observed. At a mean follow-up of 18.7 +/- 12.8 months, no mortality or morbidity including new-onset endoleak, stent-graft migration and thrombosis of supra-aortic grafts were recorded.
  
  
  CONCLUSIONS
  Endovascular treatment of aortic arch pathology is feasible even in elderly patients. However, accurate placement in the arch and aneurysm sealing with the currently available devices, may be challenging due to the involvement of supra-aortic vessels, the anatomical curvature of the arch, the high blood flow, and substantial movement of the aorta with each heartbeat.
authors.affiliation: Università Vita-Salute San Raffaele, Milano. g.melissano@hsr.it
authors.forename: Germano
authors.initials: G
authors.lastname: Melissano
authors.forename: Efrem
authors.initials: E
authors.lastname: Civilini
authors.forename: Francesco
authors.initials: F
authors.lastname: Maisano
authors.forename: Alessandro
authors.initials: A
authors.lastname: Castiglioni
authors.forename: Luca
authors.initials: L
authors.lastname: Asso Bertoglio
authors.forename: Francesco
authors.initials: F
authors.lastname: Setacci
authors.forename: Andrea
authors.initials: A
authors.lastname: Carozzo
authors.forename: Silvio
authors.initials: S
authors.lastname: Magrin
authors.forename: Alberto
authors.initials: A
authors.lastname: Zangrillo
authors.forename: Giovanni
authors.initials: G
authors.lastname: La Canna
authors.forename: Ottavio
authors.initials: O
authors.lastname: Alfieri
authors.forename: Roberto
authors.initials: R
authors.lastname: Chiesa
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D047549:Coronary Artery Bypass, Off-Pump; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome