title: Resources involved in managing retinal detachment complicated by proliferative vitreoretinopathy.
abstract: OBJECTIVE
  To report the differences in cost of treatment and outcome in retinal detachment (RD) cases with and without proliferative vitreoretinopathy (PVR).
  
  
  METHODS
  Analysis of clinical trial databases of RD observed in 190 eyes of 190 patients. Eyes were classified as no PVR, developing PVR, or established PVR. For each eye, total cost of treatment undertaken on Moorfields Eye Hospital vitreoretinal unit, final retinal status, and best-corrected visual acuity were recorded.
  
  
  RESULTS
  Management of patients who developed PVR involved approximately double the resources of RD without PVR. Eyes with pre-exiting PVR had similar resource input to those with RD without PVR. Patients who developed PVR had a mean of 3.7 operations (including subsequent cataract surgery) compared to 1.8 and 2.1 respectively for noncomplicated RD and pre-existing PVR. Anatomic success and visual outcome was significantly worse in eyes with PVR.
  
  
  CONCLUSIONS
  Treatment of eyes that developed PVR after initial surgery cost significantly more than eyes with no PVR or established PVR (P < 0.01). Improvements in the management of RD aimed at preventing PVR and advances in PVR treatment may have significant financial as well as clinical benefits.
authors.affiliation: Moorfields Eye Hospital, City Road, London, United Kingdom.
authors.forename: Nandesh N
authors.initials: NN
authors.lastname: Patel
authors.forename: Catey
authors.initials: C
authors.lastname: Bunce
authors.forename: Riaz H
authors.initials: RH
authors.lastname: Asaria
authors.forename: David G
authors.initials: DG
authors.lastname: Charteris
mesh_terms: D000293:Adolescent; D000328:Adult; D017281:Cost of Illness; D016208:Databases, Factual; D003695:Delivery of Health Care / Q000191:economics / Q000706:statistics & numerical data*; D005260:Female; D017048:Health Care Costs; D006295:Health Resources / Q000191:economics / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013508:Ophthalmologic Surgical Procedures / Q000706:statistics & numerical data; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D012163:Retinal Detachment / Q000150:complications / Q000191:economics / Q000601:surgery*; D006113:United Kingdom; D014792:Visual Acuity; D018630:Vitreoretinopathy, Proliferative / Q000191:economics / Q000209:etiology / Q000601:surgery*