Nonlinear-analysis of human sleep EEG using detrended fluctuation analysis.
Quantification of the fractal scaling properties of human sleep EEG dynamics was sought and each normal sleep stage was compared with that of sleep apnea. The fractal scaling exponents that quantify power-law correlations were computed using detrended fluctuation analysis. Six healthy subjects, aged 30-35 years, participated and six recordings of the apnea were acquired from MIT/BIH polysomnography database. The data were 8-h baseline recordings (23:00-07:00 h). The EEG signals from the C4-A1 derivation were acquired with a resolution of 250 Hz. The sleep stages were visually scored for 30 s epochs, according to the criteria of Rechtschaffen and Kales. The mean scaling exponents increased from the awake stage to stages 1, 2 and 3-4, but decreased during rapid eye movement (REM) sleep. The scaling exponents of the apnea were lower than those of the healthy subject for all the stages. The scaling exponents could be attributed to the fractal nature of EEG, which would be more appropriate for describing the complexity of EEG due to its assumption of non-stationarity.
Lee
Jong-Min
JM
Department of Biomedical Engineering, College of Medicine, Hanyang University, Sungdong, P.O. Box 55, Seoul 133-605, South Korea.
Kim
Dae-Jin
DJ
Kim
In-Young
IY
Suk Park
Kwang
K
Kim
Sun I
SI
D000328:Adult; D000465:Algorithms; D001921:Brain / Q000503:physiopathology*; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D017709:Fractals; D006801:Humans; D008297:Male; D008959:Models, Neurological; D017711:Nonlinear Dynamics; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012890:Sleep; D012891:Sleep Apnea Syndromes / Q000175:diagnosis / Q000503:physiopathology*; D014851:Wakefulness