title: The production and interpretation of disease mapsA methodological case-study.
abstract: BACKGROUND
  The study of the spatial variation in disease incidence is a vital component of descriptive epidemiology. The production of attractive and informative disease maps complements any formal statistical analyses of spatial variations and often their visual impact will influence the recipient of the information much more than the accompanying statistics. Like any other graphical display, however, a map can both inform and mislead.
  
  
  METHODS
  We describe methodological alternatives and pitfalls for the production of disease maps using data on recent suicides in England and Wales as an illustrative example.
  
  
  RESULTS
  Decisions concerning the methods of mapping of suicide rates, including smoothing, choice of grouping criteria and colouring scheme dramatically influence the resulting map and how it might be interpreted by the reader.
  
  
  CONCLUSIONS
  This study provides clinicians and other non-specialist research workers an insight into the methodological pitfalls of disease mapping and atlas production and should also act as a methodological framework for a critical appraisal of published maps and atlases.
authors.affiliation: Biostatistics Group, School of Epidemiology & Health Sciences, Stopford Building, Oxford Road, Manchester M13 9PT, UK.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Rezaeian
authors.forename: Graham
authors.initials: G
authors.lastname: Dunn
authors.forename: Selwyn
authors.initials: S
authors.lastname: St Leger
authors.forename: Louis
authors.initials: L
authors.lastname: Appleby
mesh_terms: D002423:Cause of Death; D003430:Cross-Sectional Studies; D004739:England; D006801:Humans; D015994:Incidence; D009026:Mortality; D011159:Population Surveillance; D015203:Reproducibility of Results; D013405:Suicide / Q000706:statistics & numerical data*; D019371:Topography, Medical / Q000379:methods*; D014852:Wales