Two-component 10-23 DNA enzymes.
A new strategy for engineering of catalytic two-component constructions based on 10-23 DNAzyme was proposed. The using of a combination of shortened DNAzyme with 2'-O-methyl oligomers as effectors significantly increased the catalytic activity of this DNAzyme.
Fokina
A A
AA
Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia.
Kuznetsova
M A
MA
Repkova
M N
MN
Venyaminova
A G
AG
D001483:Base Sequence; D002384:Catalysis; D021881:DNA, Catalytic / Q000737:chemistry* / Q000378:metabolism; D004277:DNA, Single-Stranded / Q000737:chemistry* / Q000378:metabolism; D009690:Nucleic Acid Conformation
D021881:DNA, Catalytic; D004277:DNA, Single-Stranded; C402582:RNA-cleaving DNA 10-23