An enantioselective fluorescent sensor for sugar acids.
Chiral fluorescent boronic acid 1 was found to be a highly enantioselective, chemoselective, and sensitive sensor for sugar acids, such as tartaric acid. Enantioselectivities (K(R)/K(S)) of up to 550:1, chemoselectivity up to 11,000:1, and sensitivities in the micromolar range with sensor 1 were observed. Single-crystal X-ray analysis was used to confirm the structure of the fluorescent species.
Zhao
Jianzhang
J
Department of Chemistry and Bath Chemical Crystallography, University of Bath, Bath BA2 7AY, UK.
Davidson
Matthew G
MG
Mahon
Mary F
MF
Kociok-Köhn
Gabriele
G
James
Tony D
TD
D001897:Boronic Acids / Q000032:analysis / Q000737:chemistry; D018360:Crystallography, X-Ray; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008958:Models, Molecular; D013050:Spectrometry, Fluorescence; D013237:Stereoisomerism; D013400:Sugar Acids / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism; D017186:Titrimetry
D001897:Boronic Acids; D005456:Fluorescent Dyes; D013400:Sugar Acids