title: Development of counterpulsation algorithm for a moving-actuator type pulsatile LVAD.
abstract: A pulsatile left ventricular assist device (LVAD) was used to support the aortic blood pumping function of an injured left ventricle, and as a result helped its recovery. It is important to observe a left ventricle's pumping status and to adjust the operating status of a LVAD to reduce the left ventricle's pumping load and thus to enhance its recovery. To observe the left ventricle's pumping status, an electrocardiogram (ECG) signal is generally used because it is a result of the natural heart's blood pumping function. In this paper, we describe the development of an ECG based counterpulsation control algorithm that prevents simultaneous aortic blood co-pumping by a left ventricle and a moving-actuator type pulsatile LVAD and as a result, reduces the natural heart's pumping load. In addition, to verify the algorithm's applicability for LVAD control we designed three ECG based automatic pump control algorithms that use a developed counterpulsation control algorithm. These algorithms control the operating status of a LVAD automatically and, at the same time, maintain a counterpulsing status. The results of in vitro experiments show that the counterpulsing effect between a left ventricle and a LVAD was successfully produced and that the newly designed automatic pump control algorithms met their own control purposes with a counterpulsing effect.
authors.affiliation: Interdisciplinary Program of Medical and Biological Engineering Major, Seoul National University, Seoul - Korea.
authors.forename: K W
authors.initials: KW
authors.lastname: Nam
authors.forename: J
authors.initials: J
authors.lastname: Chung
authors.forename: S W
authors.initials: SW
authors.lastname: Choi
authors.forename: W E
authors.initials: WE
authors.lastname: Kim
authors.forename: K
authors.initials: K
authors.lastname: Sun
authors.forename: B G
authors.initials: BG
authors.lastname: Min
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D015908:Counterpulsation / Q000379:methods*; D004562:Electrocardiography; D004867:Equipment Design; D006353:Heart-Assist Devices; D006801:Humans; D008955:Models, Cardiovascular; D012815:Signal Processing, Computer-Assisted; D018487:Ventricular Dysfunction, Left / Q000628:therapy*