[Effect of magnesium on neural activities in vitro].
It has been well known that magnesium ion (Mg(2+)) plays an important role in biological functions, especially in neural activities and functions. However, not so many researches have been carried to this subject. Here we investigated the Mg(2+)effect on neuronal electrical activities together with NMDA receptor and synaptic glutamate release by using Multi-Electrode Array (MEA) and Enzyme modified MEA-based multi-array sensor.
Torimitsu
Keiichi
K
NTT Basic Research Laboratories, NTT Corporation, SORST/JST.
Kasai
Nahoko
N
Furukawa
Yuriko
Y
D000200:Action Potentials; D000818:Animals; D015374:Biosensing Techniques; D002478:Cells, Cultured; D002540:Cerebral Cortex / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D018698:Glutamic Acid / Q000378:metabolism; D006624:Hippocampus / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D008274:Magnesium / Q000494:pharmacology / Q000502:physiology*; D008839:Microelectrodes; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors
D016194:Receptors, N-Methyl-D-Aspartate; D018698:Glutamic Acid; D008274:Magnesium