title: [The application and advancement of rapid prototyping technology in bone tissue engineering].
abstract: In bone tissue engineering, a highly porous artificial extracellular matrix or scaffold is essential to the attachment, proliferation and differentiation of bone cells (osteoblast, osteoclast and osteocytes) and the formation of bone tissue. However, conventional scaffold materials for bone tissue engineering proved less valuable for actual applications because they lack mechanical strength, interconnected channel network, and controllable porosity or channel size. Therefore,to explore the ideal scaffold materials is one of the popular studies on current bone tissue engineering. In this paper, we review, the application and advancement of a newly-developed technology generally known as rapid prototyping (RP) techniques in bone tissue engineering.
authors.affiliation: Bioengineering College and National Key Laboratory on Biomechanics & Tissue Engineering under the State Education Ministry of China, Chongqing Uniersity, Chongqing 400044, China.
authors.forename: Chuanglong
authors.initials: C
authors.lastname: He
authors.forename: Liewen
authors.initials: L
authors.lastname: Xia
authors.forename: Yanfeng
authors.initials: Y
authors.lastname: Luo
authors.forename: Yuanliang
authors.initials: Y
authors.lastname: Wang
mesh_terms: D018786:Bone Substitutes; D001842:Bone and Bones; D002454:Cell Differentiation; D002455:Cell Division; D002478:Cells, Cultured; D005109:Extracellular Matrix; D006801:Humans; D010006:Osteoblasts / Q000166:cytology*; D016062:Porosity; D023822:Tissue Engineering
chemical_list: D018786:Bone Substitutes