title: Chromosome-encoded CTX-M-3 from Kluyvera ascorbata: a possible origin of plasmid-borne CTX-M-1-derived cefotaximases.
abstract: A gene identical to plasmid-borne bla(CTX-M-3) is present in the chromosome of one Kluyvera ascorbata strain. It is associated with a structure including an inverted repeat right and an open reading frame 477-like gene probably involved in the mobilization of bla(CTX-M-3). Two other K. ascorbata strains rendered the previously described bla(KLUA-9) gene.
authors.affiliation: Cátedra de Microbiología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
authors.forename: María Margarita
authors.initials: MM
authors.lastname: Rodríguez
authors.forename: Pablo
authors.initials: P
authors.lastname: Power
authors.forename: Marcela
authors.initials: M
authors.lastname: Radice
authors.forename: Carlos
authors.initials: C
authors.lastname: Vay
authors.forename: Angela
authors.initials: A
authors.lastname: Famiglietti
authors.forename: Moreno
authors.initials: M
authors.lastname: Galleni
authors.forename: Juan A
authors.initials: JA
authors.lastname: Ayala
authors.forename: Gabriel
authors.initials: G
authors.lastname: Gutkind
mesh_terms: D004926:Escherichia coli / Q000235:genetics; D007525:Isoelectric Focusing; D044086:Kluyvera / Q000201:enzymology* / Q000235:genetics*; D008969:Molecular Sequence Data; D016366:Open Reading Frames / Q000235:genetics; D010957:Plasmids / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: C071167:beta-lactamase CTX-2; C417271:beta-lactamase CTX-M-3; D001618:beta-Lactamases