title: Two distinct STLV-1 subtypes infecting Mandrillus sphinx follow the geographic distribution of their hosts.
abstract: The mandrill (Mandrillus sphinx) has been shown to be infected with an STLV-1 closely related to HTLV-1. Two distinct STLV-1 subtypes (D and F) infect wild mandrills with high overall prevalence (27.0%) but are different with respect to their phylogenetic relationship and parallel to the mandrills' geographic range. The clustering of these new STLV-1mnd sequences with HTLV-1 subtype D and F suggests first, past simian-to-human transmissions in Central Africa and second, that species barriers are easier to cross over than geographic barriers.
authors.affiliation: Laboratoire de Virologie, UGENET, CDP, SEGC-Lopé, Centre International de Recherches Médicales, Franceville, Gabon. mmakuwa@yahoo.com
authors.forename: M
authors.initials: M
authors.lastname: Makuwa
authors.forename: S
authors.initials: S
authors.lastname: Souquière
authors.forename: S L
authors.initials: SL
authors.lastname: Clifford
authors.forename: P T
authors.initials: PT
authors.lastname: Telfer
authors.forename: B
authors.initials: B
authors.lastname: Sallé
authors.forename: O
authors.initials: O
authors.lastname: Bourry
authors.forename: R
authors.initials: R
authors.lastname: Onanga
authors.forename: A
authors.initials: A
authors.lastname: Mouinga-Ondeme
authors.forename: E J
authors.initials: EJ
authors.lastname: Wickings
authors.forename: K A
authors.initials: KA
authors.lastname: Abernethy
authors.forename: P
authors.initials: P
authors.lastname: Rouquet
authors.forename: F
authors.initials: F
authors.lastname: Simon
authors.forename: P
authors.initials: P
authors.lastname: Roques
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D006800:Deltaretrovirus Infections / Q000662:veterinary* / Q000821:virology; D005260:Female; D005681:Gabon; D016356:Gene Products, tax / Q000737:chemistry / Q000235:genetics; D008297:Male; D048528:Mandrillus / Q000502:physiology / Q000821:virology*; D008969:Molecular Sequence Data; D008992:Monkey Diseases / Q000821:virology*; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D015303:Simian T-lymphotropic virus 1 / Q000145:classification* / Q000235:genetics / Q000472:pathogenicity
chemical_list: D016356:Gene Products, tax