title: [Guided bone regeneration beneath titanium foils].
abstract: The aim of this study was to examine the clinical and histological bony healing process beneath titanium foils used for guided tissue regeneration as well as of the Frios Algipore graft which was applied with autologous bone. 66 sinus floor elevations were carried out and examined over a period of three years and eight months. A success rate of 64% was recorded with foil incorporation. Complications occurred in form of primary and secondary disturbances in the healing process caused by exposure of the foil. 12 of the 66 foils had to be removed early. In all but one case, the augmented bone material was macroscopically well integrated despite the loss of the foil. Primary stability of the inserted dental implants into the ossified augmented site after operations of the sinus maxillaris was reached in all cases with absence of post-operative complications, and in 94% when there was postoperative exposure of the membrane. Histologically, a thin layer of connective tissue poor in cells but rich in collagen fibers appeared underneath the titanium foil. This was followed by newly-formed bony tissue transforming into osseous lamella parallel to the membrane underneath the new periost. In 65 out of 66 cases a sufficient amount of stable bone was built up locally suggesting good bio-compatibility and barrier function. Further, the foil also provided mechanical rest and supporting function for the space underneath. However, the occurrence of healing complications in 36% of the cases showed a need to improve on the titanium foils.
authors.affiliation: Poliklinik für zahnärztliche Prothetik und Werkstoffkunde, Zentrum für Zahn-, Mund- und Kieferheilkunde der Universität Leipzig.
authors.forename: Katharina
authors.initials: K
authors.lastname: Otto
authors.forename: Christian
authors.initials: C
authors.lastname: Schopper
authors.forename: Rolf
authors.initials: R
authors.lastname: Ewers
authors.forename: J Thomas
authors.initials: JT
authors.lastname: Lambrecht
mesh_terms: D001861:Bone Regeneration; D018786:Bone Substitutes; D016025:Bone Transplantation; D003758:Dental Implantation, Endosseous; D016557:Guided Tissue Regeneration, Periodontal / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008443:Maxillary Sinus / Q000601:surgery*; D008567:Membranes, Artificial; D013516:Oral Surgical Procedures, Preprosthetic; D011183:Postoperative Complications; D012189:Retrospective Studies; D014025:Titanium; D016896:Treatment Outcome
chemical_list: C483718:Algipore; D018786:Bone Substitutes; D008567:Membranes, Artificial; D014025:Titanium