[Acute psychosis after administration of bupropion hydrochloride (Zyban)].
A 29-year old had been admitted to our institution with acute onset of schizophreniform psychosis after 5-day administration of sustained-release bupropion hydrochloride, which had been prescribed for nicotine withdrawal in a daily dosage of 300 mg. Examination results were found to be completely normal, apart from a positive drug screen for cannabis. We hypothesize that bupropion had induced psychotic symptoms in this patient.
Neumann
Marcus
M
Bezirksklinikum Gabersee. marcus.neumann@gabersee.de
Livak
Vitali
V
Paul
Hans-Werner
HW
D000208:Acute Disease; D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects* / Q000627:therapeutic use; D016642:Bupropion / Q000009:adverse effects* / Q000627:therapeutic use; D003692:Delayed-Action Preparations; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D009483:Neuropsychological Tests; D011605:Psychoses, Substance-Induced / Q000209:etiology*; D011618:Psychotic Disorders / Q000175:diagnosis / Q000523:psychology; D014029:Tobacco Use Disorder / Q000534:rehabilitation
D018687:Antidepressive Agents, Second-Generation; D003692:Delayed-Action Preparations; D016642:Bupropion