[Observation of clinical response of "sheng ban recipe" for platelets decrease after chemotherapy].
OBJECTIVE
The majority of cancer chemotherapy can lead to bone marrow depression, which often affects clinical response as chemotherapy can not be carried out with enough dosage on time. The platelets decrease is one of the problems caused by bone marrow depression. Though the clinical response of hyodermic "IL-11" is affirmed to advance platelets presently, it is limited by expensive price. Other agents that can be taken orally with suitable price and equal authenticity are less reported. The author observed clinical response of platelets decrease adopting traditional Chinese medicine "Sheng Ban Recipe"(SBR).


METHODS
Totally 103 patients with platelets decrease after chemotherapy from July 1994 to Jannary 2002. They were randomly divided into two groups: SBR plus common treatment group and common treatment alone group. The previous group take 1 package SBR for twice drink per day. Common treatment group give common therapy only. The follow-up period is 2 weeks.


RESULTS
Among the 55 cases in SBR group, noticeable efficiency 20%, efficiency 50.9%, total efficiency 70.9%, which is evidently superior to common group.


CONCLUSIONS
"Sheng Ban Recipe" can effectively treat thrombocytopenia after chemotherapy, which helps to reduce the necessary of intravenous drip of platelets and the risk of hemorrhage.
Zhang
Bei
B
Department of Traditional Chinese Medicine, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, 510060, R.P. China. Zb6336@hotmail.com
Hu
Pi-Li
PL
Qiu
Hui-Juan
HJ
Qian
Sui-Yi
SY
Chen
Xu-Xian
XX
Huang
Guo-Xian
GX
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy*; D008223:Lymphoma / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D010976:Platelet Count; D013921:Thrombocytopenia / Q000139:chemically induced / Q000188:drug therapy*
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal