title: [Resection of giant pituitary adenomas through transnasal and transsphenoidal approach with nasoendoscope].
abstract: OBJECTIVE
  To investigate the feasibility of transnasal and transsphenoidal surgery for giant pituitary adenomas with nasoendoscope.
  
  
  METHODS
  The giant pituitary adenomas were resected by the transnasal and transsphenoidal surgery with nasoendoscope in 13 patients.
  
  
  RESULTS
  The tumors were totally resected in 9 cases (69.2%), subtotally in 3 cases (23.1%) and the resection failed in 1 (7.7%). Vision and visual field were significantly improved in 10 patients (76.9%) one week after the operations, of whom 7 had nearly or completely normal vision and visual field. There were no serious complications or death except transient cerebro spinal fluid leakage in 2 patients.
  
  
  CONCLUSIONS
  It should be noted that the operative manipulation and curative effect of nasoendoscopic surgery on the giant pituitary adenomas may be affected by some factors such as the hemorrhage during the operation, anatomical abnormality, parasellar tissue projecting into the sella, postoperative improper treatment and so on.
authors.affiliation: Department of Otolaryngology, Wuhan General Hospital of Guangzhou Military Command, Wuhan, 430070, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Zhang
authors.forename: Wuyan
authors.initials: W
authors.lastname: Lin
authors.forename: Xingqi
authors.initials: X
authors.lastname: Yao
mesh_terms: D000236:Adenoma / Q000601:surgery*; D000328:Adult; D000368:Aged; D004724:Endoscopy; D005260:Female; D006801:Humans; D007016:Hypophysectomy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000601:surgery*