Alcoholic ketoacidosis associated with multiple complications: report of 3 cases.
We report 3 patients with alcoholic ketoacidosis (AKA). All had a history of excessive intake and abrupt termination of alcohol. They showed tachypnea, tachycardia, abdominal tenderness, and epigastralgia. Metabolic acidosis with an increased anion gap, decreased PaCO2 and ketonemia were present. One patient whose ratio of 3-hydroxybutyric acid to acetoacetic acid was 4.0 was associated with diabetic ketoacidosis. All patients were successfully hydrated with electrolyte, glucose and thiamine. Complications such as liver dysfunction, lactic acidosis, acute pancreatitis, Wernicke's encephalopathy, rhabdomyolysis and heart failure were present. Attention should be paid to multiple complications in the treatment of AKA.
Tanaka
Masami
M
Department of Internal Medicine, Misato Kenwa Hospital, 4-494-1 Takano, Misato, Saitama 341-8555.
Miyazaki
Yasushi
Y
Ishikawa
Shinsuke
S
Matsuyama
Kimihiko
K
D000138:Acidosis / Q000209:etiology*; D000437:Alcoholism / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D003681:Dehydration / Q000209:etiology; D016883:Diabetic Ketoacidosis / Q000150:complications; D005260:Female; D005947:Glucose / Q000627:therapeutic use; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D007657:Ketone Bodies / Q000096:biosynthesis; D007662:Ketosis / Q000209:etiology* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012893:Sleep Wake Disorders / Q000209:etiology; D013610:Tachycardia / Q000209:etiology; D013831:Thiamine / Q000627:therapeutic use; D016896:Treatment Outcome
D007328:Insulin; D007657:Ketone Bodies; D005947:Glucose; D013831:Thiamine