Use of imidacloprid-permethrin to prevent transmission of Anaplasma phagocytophilum from naturally infected Ixodes scapularis ticks to dogs.
One group of eight beagles was treated with a combination of imidacloprid and permethrin 7 days before exposure to Ixodes scapularis ticks that were naturally infected with Anaplasma phagocytophilum. A second group of eight beagles was not treated and was also exposed to infected ticks. Seven of eight non-treated dogs--but none of the treated dogs--developed specific antibodies to A. phagocytophilum. Results of this study indicate that a combination of imidacloprid and permethrin can prevent transmission of A. phagocytophilum to dogs if administered before exposure to infected ticks.
Blagburn
Byron L
BL
Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849, USA.
Spencer
Jennifer A
JA
Billeter
Sarah A
SA
Drazenovich
Nicole L
NL
Butler
Jamie M
JM
Land
Tracey M
TM
Dykstra
Christine C
CC
Stafford
Kirby C
KC
Pough
Margaret B
MB
Levy
Steven A
SA
Bledsoe
David L
DL
D041081:Anaplasma phagocytophilum; D000818:Animals; D001096:Arachnid Vectors / Q000382:microbiology*; D004283:Dog Diseases / Q000517:prevention & control* / Q000635:transmission; D004285:Dogs; D016873:Ehrlichiosis / Q000517:prevention & control / Q000635:transmission / Q000662:veterinary*; D005260:Female; D007093:Imidazoles / Q000627:therapeutic use; D007306:Insecticides / Q000627:therapeutic use*; D018884:Ixodes / Q000382:microbiology*; D008297:Male; D000073943:Neonicotinoids; D009574:Nitro Compounds; D026023:Permethrin / Q000627:therapeutic use; D011897:Random Allocation; D013984:Tick Infestations / Q000517:prevention & control / Q000662:veterinary*; D013997:Time Factors; D016896:Treatment Outcome
D007093:Imidazoles; D007306:Insecticides; D000073943:Neonicotinoids; D009574:Nitro Compounds; C082359:imidacloprid; D026023:Permethrin