[Expression of macrophage migration inhibition factor in pancreatic carcinoma tissue].
OBJECTIVE
To observe the expression of macrophage migration inhibitory factor (MIF) in pancreatic carcinoma tissue and analyze the relationship between MIF expression and clinical manifestations.


METHODS
MIF expression in pancreatic carcinoma and normal pancreatic tissue were detected with immunohistochemical method.


RESULTS
The positivity rates of MIF in pancreatic carcinoma and normal pancreatic tissue were 69.4% (25/36) and 0 (0/10) respectively. MIF expression was found to relate to the degree of cell differentiation of pancreatic carcinoma, but not to the clinical stages or the status of lymph node metastasis.


CONCLUSIONS
MIF might be related to the pathogenesis of pancreatic carcinoma.
Jin
Zhi-qing
ZQ
Institute for Digestive Disease of PLA, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. potatoneimeng@163.com
Zhi
Fa-chao
FC
Chen
Xue-qing
XQ
Wang
Ya-dong
YD
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008263:Macrophage Migration-Inhibitory Factors / Q000096:biosynthesis* / Q000235:genetics; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000378:metabolism*; D010190:Pancreatic Neoplasms / Q000378:metabolism* / Q000473:pathology
D008263:Macrophage Migration-Inhibitory Factors