Anti-tuberculosis activity of some N-pentopyranosylamines.
With the advent of multidrug-resistant Mycobacterium tuberculosis, new effective drugs are rapidly needed. Thirty-two derivatives of some N-pentopyranosylamines were prepared and tested under the Tuberculosis Antimicrobial Acquisition and Coordinating Facility (TAACF) program. This communication is presenting their antituberculosis activity in the primary screen.
Moczulska
Antonina
A
Department of Chemistry, Institute of Biology and Environment Protection, The Pedagogic University, 22 Arciszewskiego Str., 76-200 Słupsk, Poland.
D000606:Amino Sugars / Q000737:chemistry / Q000494:pharmacology*; D000995:Antitubercular Agents / Q000737:chemistry / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D013329:Structure-Activity Relationship
D000606:Amino Sugars; D000995:Antitubercular Agents