title: Circulating tenascin-C levels in patients with idiopathic dilated cardiomyopathy.
abstract: Circulating serum tenascin-C (an extracellular matrix glycoprotein) levels in patients with idiopathic dilated cardiomyopathy (IDC) were measured. Serum tenascin-C levels were increased in proportion to the severity of left ventricular dysfunction in patients with IDC. The associations of serum tenascin-C levels with serum troponin T and procollagen type III aminoterminal peptide levels suggest that increased levels of serum tenascin-C indicate ongoing replacement fibrosis after myocardial damage in IDC.
authors.affiliation: Second Department of Internal Medicine, Oita University, Oita, Japan.
authors.forename: Nobuko
authors.initials: N
authors.lastname: Aso
authors.forename: Akira
authors.initials: A
authors.lastname: Tamura
authors.forename: Masaru
authors.initials: M
authors.lastname: Nasu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood*; D002311:Cardiomyopathy, Dilated / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012720:Severity of Illness Index; D019063:Tenascin / Q000097:blood*; D018487:Ventricular Dysfunction, Left
chemical_list: D015415:Biomarkers; D019063:Tenascin