title: Primary presentation of glioblastoma multiforme with leptomeningeal metastasis in the absence of previous craniotomy: a case report.
abstract: Glioblastoma multiforme is a highly malignant glioma with a well-known tendency for intracranial spread but rarely for extracranial spread. We report a case of an adult woman who presented with symptoms of leptomeningeal metastasis from an intracranial glioblastoma multiforme located adjacent to the lateral ventricle. There have been very few cases of glioblastoma multiforme presenting with leptomeningeal metastasis in the absence of previous therapeutic intervention.
authors.affiliation: Department of Radiation Oncology, SUNY Upstate Medical University, Syracuse, NY 13210, USA. pohars@upstate.edu
authors.forename: Surjeet
authors.initials: S
authors.lastname: Pohar
authors.forename: William
authors.initials: W
authors.lastname: Taylor
authors.forename: Vishal S
authors.initials: VS
authors.lastname: Chandan
authors.forename: Hemangini
authors.initials: H
authors.lastname: Shah
authors.forename: Robert H
authors.initials: RH
authors.lastname: Sagerman
mesh_terms: D002551:Cerebral Ventricle Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D005909:Glioblastoma / Q000175:diagnosis / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D013120:Spinal Cord Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000556:secondary*