title: Prenylated benzophenones and xanthones from Hypericum scabrum.
abstract: Two new polyprenylated benzophenones, a new polyprenylated phloroglucinol, and six new xanthone derivatives were isolated from the aerial parts of the Uzbekistan medicinal plant Hypericum scabrum. Their structures were elucidated on the basis of spectroscopic evidence. The isolated compounds showed moderate cytotoxicity for human tumor cells.
authors.affiliation: Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan.
authors.forename: Naonobu
authors.initials: N
authors.lastname: Tanaka
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Takaishi
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Shikishima
authors.forename: Yuka
authors.initials: Y
authors.lastname: Nakanishi
authors.forename: Kenneth
authors.initials: K
authors.lastname: Bastow
authors.forename: Kuo-Hsiung
authors.initials: KH
authors.lastname: Lee
authors.forename: Gisho
authors.initials: G
authors.lastname: Honda
authors.forename: Michiho
authors.initials: M
authors.lastname: Ito
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Takeda
authors.forename: Olimjon K
authors.initials: OK
authors.lastname: Kodzhimatov
authors.forename: Ozodbek
authors.initials: O
authors.lastname: Ashurmetov
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001577:Benzophenones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D020902:Hypericum / Q000737:chemistry*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D014407:Tumor Cells, Cultured; D014610:Uzbekistan; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D001577:Benzophenones; D044004:Xanthones