Microscopic polyangiitis sparing the kidneys in a long-term survivor after allogenic bone marrow transplantation and graft-versus-host disease.
We report an unusual case of microscopic polyangiitis sparing the kidneys in a long-term survivor of allogenic bone marrow transplantation. Clinical and pathologic studies revealed cutaneous leukocytoclastic vasculitis and isolated pulmonary capillaritis. Serological studies revealed "double positive": perinuclear antineutrophil cytoplasmic (p-ANCA) antibody testing with anti-myeloperoxidase (MPO) activity and anti-glomerular basement membrane (anti-GBM) antibody. The vasculitis has been successfully controlled with prednisone and cyclophosphamide.
Almoallim
Hani
H
Department of Medicine, Medical College, Umm Alqura University Makkah, P.O. Box 1821, Jeddah 21441, Saudi Arabia. hanialmoallim@hotmail.com
Caroline Patterson
A
A
D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D005260:Female; D006086:Graft vs Host Disease / Q000150:complications*; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D008833:Microcirculation; D008875:Middle Aged; D011652:Pulmonary Circulation; D012079:Renal Circulation; D017741:Survivors; D014184:Transplantation, Homologous; D014657:Vasculitis / Q000209:etiology*