title: Promethazine: a novel application as a neuroprotectant that reduces ischemia-mediated injury by inhibiting mitochondrial dysfunction.
authors.affiliation: Department of Neurosurgery, Brigham and Women's Hospital, Harvard University Medical School, Boston, Massachusetts, USA.
authors.forename: Malini V
authors.initials: MV
authors.lastname: Narayanan
authors.forename: Wenhua
authors.initials: W
authors.lastname: Zhang
authors.forename: Irina G
authors.initials: IG
authors.lastname: Stavrovskaya
authors.forename: Bruce S
authors.initials: BS
authors.lastname: Kristal
authors.forename: Robert M
authors.initials: RM
authors.lastname: Friedlander
mesh_terms: D000818:Animals; D015153:Blotting, Western; D002545:Brain Ischemia / Q000150:complications / Q000517:prevention & control*; D016923:Cell Death; D002540:Cerebral Cortex / Q000187:drug effects / Q000473:pathology; D006634:Histamine H1 Antagonists / Q000494:pharmacology* / Q000627:therapeutic use*; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D028361:Mitochondrial Diseases / Q000209:etiology / Q000517:prevention & control*; D018696:Neuroprotective Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D011398:Promethazine / Q000494:pharmacology* / Q000627:therapeutic use*
chemical_list: D006634:Histamine H1 Antagonists; D018696:Neuroprotective Agents; D011398:Promethazine