[Antipsychotics and memory functions in schizophrenic patients].
OBJECTIVE
The aim of this study was to evaluate the effects of antipsychotics on memory functions in schizophrenic patients under clinical routine conditions.


METHODS
Schizophrenic patients (n = 111) before discharge to outpatient treatment were evaluated on verbal memory function. Data were analyzed according to pharmacological treatment controlling for age.


RESULTS
We observed that treatment with atypical antipsychotics (n = 80) compared with conventional neuroleptics (n = 31) was significantly associated with a more favorable effect on memory function. In short-term- and working-memory and retention a clear advantage of atypical antipsychotics could be seen.


CONCLUSIONS
Results from this study suggest that even under clinical routine conditions atypical antipsychotics have an advantage on memory function when compared with conventional antipsychotics.
Brunnauer
Alexander
A
Bezirksklinikum Gabersee, Fachkrankenhaus für Psychiatrie, Psychotherapie und Neurologie. brunnauer.alexander@gabersee.de
Geiger
Elisabeth
E
Laux
Gerd
G
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008570:Memory, Short-Term / Q000187:drug effects*; D008875:Middle Aged; D009483:Neuropsychological Tests; D012559:Schizophrenia / Q000188:drug therapy*; D012565:Schizophrenic Psychology; D016896:Treatment Outcome; D014706:Verbal Learning / Q000187:drug effects*