title: The F-ATPase operon promoter of Streptococcus mutans is transcriptionally regulated in response to external pH.
abstract: Streptococcus mutans F-ATPase, the major component of the acid-adaptive response of the organism, is transcriptionally upregulated at low pH. Fusions of the F-ATPase promoter to chloramphenicol acetyltransferase indicated that pH-dependent expression is still observed with a short promoter that contains a domain conserved between streptococcal ATPase operons.
authors.affiliation: Center for Oral Biology, Box 611, 601 Elmwood Ave., Rochester, NY 14642, USA.
authors.forename: Wendi L
authors.initials: WL
authors.lastname: Kuhnert
authors.forename: Guolu
authors.initials: G
authors.lastname: Zheng
authors.forename: Roberta C
authors.initials: RC
authors.lastname: Faustoferri
authors.forename: Robert G
authors.initials: RG
authors.lastname: Quivey
mesh_terms: D025243:Bacterial Proton-Translocating ATPases / Q000235:genetics / Q000378:metabolism*; D001483:Base Sequence; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008969:Molecular Sequence Data; D009876:Operon; D011401:Promoter Regions, Genetic; D013295:Streptococcus mutans / Q000201:enzymology* / Q000235:genetics / Q000254:growth & development; D014158:Transcription, Genetic
chemical_list: D025243:Bacterial Proton-Translocating ATPases