title: Cardiopulmonary bypass: it's not the size, it's how you use it! Review of a comprehensive blood-conservation strategy.
abstract: Several of the manufacturers of cardiopulmonary bypass equipment have recently introduced new miniature cardiopulmonary bypass systems. New advancements in cardiopulmonary bypass technology are almost always of interest to the perfusion community. However, the question arises, what advantages do these systems offer over our present technology? The manufacturers claim that these new systems will add to our perfusion armamentarium by offering us an opportunity to further reduce priming volume and the surface area to which the blood is exposed. Our group, in the Department of Cardiac Surgery at Boston Medical Center has been involved in the development of a comprehensive blood conservation strategy since 1994. Our published data clearly demonstrates improved clinical outcomes using coated circuit technology as part of a comprehensive blood conservation strategy. In an effort to clearly evaluate this new technology, in this article we review our current technique at Boston Medical Center.
authors.affiliation: Department of Cardiothoracic Surgery, Brigham and Woman's Hospital/Cape Cod Hospital, Hyannis, MA 02601, USA. klilly@capecodhealth.org
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Lilly
authors.forename: Paul J
authors.initials: PJ
authors.lastname: O'Gara
authors.forename: Patrick R
authors.initials: PR
authors.lastname: Treanor
authors.forename: Deborah
authors.initials: D
authors.lastname: Reardon
authors.forename: Richard
authors.initials: R
authors.lastname: Crowley
authors.forename: Curtis
authors.initials: C
authors.lastname: Hunter
authors.forename: Oz M
authors.initials: OM
authors.lastname: Shapira
authors.forename: Gabriel S
authors.initials: GS
authors.lastname: Aldea
authors.forename: Harold L
authors.initials: HL
authors.lastname: Lazar
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Shemin
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage*; D001781:Blood Component Removal; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001793:Blood Preservation; D002315:Cardiopulmonary Bypass / Q000295:instrumentation* / Q000379:methods; D016503:Drug Delivery Systems; D005112:Extracorporeal Circulation / Q000379:methods*; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D008904:Miniaturization; D010973:Platelet Adhesiveness; D010976:Platelet Count; D013396:Suction
chemical_list: D000925:Anticoagulants; D006493:Heparin