Mutation of the Pax6 gene causes impaired glucose-stimulated insulin secretion.
Kuroda
A
A
Kaneto
H
H
Fujitani
Y
Y
Watada
H
H
Nakatani
Y
Y
Kajimoto
Y
Y
Matsuhisa
M
M
Yamasakai
Y
Y
Fujiwara
M
M
D000818:Animals; D015783:Aniridia / Q000235:genetics; D001120:Arginine / Q000494:pharmacology; D001786:Blood Glucose / Q000187:drug effects / Q000378:metabolism; D005136:Eye Proteins / Q000235:genetics*; D005947:Glucose / Q000494:pharmacology*; D005951:Glucose Tolerance Test; D018398:Homeodomain Proteins / Q000235:genetics*; D006801:Humans; D007328:Insulin / Q000096:biosynthesis / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000502:physiology*; D005810:Multigene Family; D000071841:PAX6 Transcription Factor; D051761:Paired Box Transcription Factors; D051381:Rats; D011922:Rats, Mutant Strains; D017207:Rats, Sprague-Dawley; D012097:Repressor Proteins / Q000235:genetics*
D001786:Blood Glucose; D005136:Eye Proteins; D018398:Homeodomain Proteins; D007328:Insulin; D000071841:PAX6 Transcription Factor; C000605730:PAX6 protein, human; D051761:Paired Box Transcription Factors; C000605733:Pax6 protein, rat; D012097:Repressor Proteins; D001120:Arginine; D005947:Glucose