Chemical diversity through biotransformations.
Diversity constitutes an intrinsic property of biosynthesis. This inherent property can be exploited and successfully applied in organic synthesis. Recent advances have been made in many areas, including the use of multifunctional enzymes and catalytic promiscuity, the synthesis of diverse products from a single substrate, the use of different biotransformations to make one product, and the use of in vivo biotransformations.
Müller
Michael
M
Institute of Biotechnology 2, Research Centre Jülich, 52425 Jülich, Germany. mi.mueller@fz-juelich.de
D001711:Biotransformation; D020650:Combinatorial Chemistry Techniques; D004798:Enzymes / Q000378:metabolism; D013379:Substrate Specificity
D004798:Enzymes