title: Lymphoplasmacyte rich meningioma. A case report and review of the literature.
abstract: A peculiar type of meningioma with conspicious plasma-cell components is described. In accordance with the World Health Organization's Histological Typing of Tumours of the Central Nervous System, this rare clinical entity is recently designed as lymphoplasmacyte rich (LPR) meningioma. This type of meningioma is usually accompanied by prominent peripheral blood abnormalities, anemia and/or policlonal gammophaty, that disappear after surgical removal of the tumor. Actually, the origin (neoplastic or inflammatory) of this tumor is unclear; its biological behavior and clinical course are anomalous so it is considered closer to intracranial inflammatory masses rather than typical meningioma. In this paper, a new case of intracranial LPR meningioma occurring in a woman, is reported and a review the literature is made.
authors.affiliation: Department of Neurosurgery, Federico II University School of Medicine, Naples, Italy. carmen975@libero.it
authors.forename: M C
authors.initials: MC
authors.lastname: Bruno
authors.forename: C
authors.initials: C
authors.lastname: Ginguené
authors.forename: M
authors.initials: M
authors.lastname: Santangelo
authors.forename: K
authors.initials: K
authors.lastname: Panagiotopoulos
authors.forename: G A
authors.initials: GA
authors.lastname: Piscopo
authors.forename: F
authors.initials: F
authors.lastname: Tortora
authors.forename: A
authors.initials: A
authors.lastname: Elefante
authors.forename: M L
authors.initials: ML
authors.lastname: De Caro
authors.forename: A
authors.initials: A
authors.lastname: Cerillo
mesh_terms: D000740:Anemia / Q000150:complications* / Q000175:diagnosis; D001402:B-Lymphocytes / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D014408:Biomarkers, Tumor / Q000096:biosynthesis; D003399:Craniotomy; D004244:Dizziness / Q000209:etiology; D005260:Female; D006261:Headache / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D008579:Meningioma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D018365:Neoplasm, Residual / Q000175:diagnosis*; D010950:Plasma Cells / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor