Increased systolic daily ambulatory blood pressure in adult women born preterm.
We have studied 24-h ambulatory blood pressure and kidney function in three groups of adult women: (1) born full term but with birth weights below the 3rd percentile for gestational age (n =18), (2) born preterm before gestational week 33 (median birth weight 1,250 g, range 950-2,040 g) (ex-preterm, n =14), and (3) those born full term with normal birth weights (comparison group n =17). We have previously published the results from the study. We recalculated the daily ambulatory blood pressure and redefined the time interval from 6:00-24:00 to 8:00-20:00, since this better corresponds to daily active life. We found significantly increased mean daily systolic ambulatory blood pressure in the ex-preterm group. The result supports the suggestion that disturbance and/or disruption of the normal prenatal milieu seem to affect arterial blood pressure in adult life.
Kistner
Anna
A
Department of Medicine, Division of Nephrology, Karolinska University Hospital Solna, 171-76 Stockholm, Sweden. anna.kistner@telia.com
Celsi
Gianni
G
Vanpée
Mireille
M
Jacobson
Stefan H
SH
D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory / Q000379:methods*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000502:physiology*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D013599:Systole