title: Fertility after ovarian drilling by transvaginal fertiloscopy for treatment of polycystic ovary syndrome.
abstract: OBJECTIVE
  To evaluate fertiloscopy ovarian drilling with bipolar energy in women with clomiphene citrate-resistant polycystic ovary syndrome (PCOS).
  
  
  METHODS
  Prospective study (Canadian Task Force classification II).
  
  
  METHODS
  University teaching hospital and private clinic.
  
  
  METHODS
  Eighty women with clomiphene citrate-resistant PCOS.
  
  
  METHODS
  Operative transvaginal fertiloscopy with a coaxial bipolar electrode.
  
  
  RESULTS
  During a mean follow-up of 18.1 months (+/- 6.4), 73 women (91%) recovered regular and ovulatory cycles. The cumulative pregnancy rate was 60% (44/73) for spontaneous and stimulated cycles, with 39.7% (29/73) imputed to drilling alone. The mean time to conceive was 3.9 months (range 1-11.8). There were eight miscarriages (18%), and no ectopic pregnancies or multiple pregnancy. No complications occurred.
  
  
  CONCLUSIONS
  Ovarian drilling by transvaginal fertiloscopy with bipolar electrosurgery appears to be an effective minimally invasive procedure in patients with PCOS resistant to clomiphene citrate.
authors.affiliation: Service de Gynécologie-Obstétrique, Hôpital Antoine Béclère, Assistance Publique-Hôpitaux de Paris, Clamart, France.
authors.forename: Hervé
authors.initials: H
authors.lastname: Fernandez
authors.forename: Antoine
authors.initials: A
authors.lastname: Watrelot
authors.forename: Jean-Dominique
authors.initials: JD
authors.lastname: Alby
authors.forename: Jacques
authors.initials: J
authors.lastname: Kadoch
authors.forename: Amélie
authors.initials: A
authors.lastname: Gervaise
authors.forename: Renaud
authors.initials: R
authors.lastname: deTayrac
authors.forename: René
authors.initials: R
authors.lastname: Frydman
mesh_terms: D000328:Adult; D002996:Clomiphene / Q000627:therapeutic use; D004598:Electrosurgery; D005260:Female; D005298:Fertility; D006801:Humans; D010053:Ovary / Q000601:surgery*; D011085:Polycystic Ovary Syndrome / Q000188:drug therapy / Q000601:surgery*; D011184:Postoperative Period; D011446:Prospective Studies; D017211:Treatment Failure
chemical_list: D002996:Clomiphene