title: [Study on the SFE condition for curcumin in Curcuma longa].
abstract: OBJECTIVE
  To optimize the conditions of supercritical fluid extraction (SFE) for curcumin in Curcuma longa.
  
  
  METHODS
  Optimum extraction conditions were studied by orthogonal tests. The extracts were analyzed by HPLC.
  
  
  RESULTS
  The optimal extraction conditions were pressure 25 MPa, temperature 55 degrees C, static time 4 h, dynamic time 5 h, flow rate of CO2 3.5 L x min(-1), co-solvent ethanol 30% (mL x g(-1)).
  
  
  CONCLUSIONS
  It is feasible to extract curcumin by SFE.
authors.affiliation: Department of Pharmaceutical Engineering of Jiangsu University, Zhenjian 212013 China. lyhssl@ujs.edu.cn
authors.forename: Shu-lan
authors.initials: SL
authors.lastname: Su
authors.forename: Qi-nan
authors.initials: QN
authors.lastname: Wu
authors.forename: Zhen
authors.initials: Z
authors.lastname: Ouyang
authors.forename: De-kang
authors.initials: DK
authors.lastname: Wu
authors.forename: Jun
authors.initials: J
authors.lastname: Chen
mesh_terms: D002245:Carbon Dioxide; D025924:Chromatography, Supercritical Fluid / Q000379:methods*; D030024:Curcuma / Q000737:chemistry*; D003474:Curcumin / Q000032:analysis / Q000302:isolation & purification*; D000431:Ethanol; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011312:Pressure; D013696:Temperature; D013997:Time Factors
chemical_list: D002245:Carbon Dioxide; D000431:Ethanol; D003474:Curcumin