Lincosamides: chemical structure, biosynthesis, mechanism of action, resistance, and applications.
Spízek
Jaroslav
J
Institute of Microbiology Academy of Sciences of the Czech Republic 142 20 Prague 4, Czech Republic. spizek@biomed.cas.cz
Novotná
Jitka
J
Rezanka
Tomás
T
D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D000981:Antiprotozoal Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D002981:Clindamycin / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D004351:Drug Resistance; D056890:Eukaryota / Q000187:drug effects; D015964:Gene Expression Regulation, Bacterial; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006801:Humans; D008034:Lincomycin / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D055231:Lincosamides; D018942:Macrolides / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D013302:Streptomyces / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D000981:Antiprotozoal Agents; D001426:Bacterial Proteins; D055231:Lincosamides; D018942:Macrolides; D002981:Clindamycin; D008034:Lincomycin