title: Cognitive function before and after surgery in patients with unruptured intracranial aneurysm.
abstract: OBJECTIVE
  This prospective study investigated whether surgery for unruptured intracranial aneurysms (UIAs) affects cognitive function and cerebral blood flow (CBF).
  
  
  METHODS
  Cognitive tests using the Wechsler Adult Intelligence Scale-Revised, Wechsler Memory Scale, Rey-Osterrieth Complex Figure test, and CBF measurements using single-photon emission computed tomography were performed before and after surgery for UIAs in 44 patients < or =70 years of age.
  
  
  RESULTS
  Group-rate analysis showed the verbal intelligence quotient (IQ), performance IQ, full-scale IQ, and recall trial scores of the Rey-Osterrieth Complex Figure test all increased significantly after surgery, whereas the Wechsler Memory Scale and copy trial scores of the Rey-Osterrieth Complex Figure test were not significantly different. Event-rate analysis demonstrated that no patient showed impaired cognition. There was no significant difference between CBF before and after surgery.
  
  
  CONCLUSIONS
  Surgical repair for UIAs does not impair cognition or CBF in patients without postoperative restrictions in lifestyle.
authors.affiliation: Department of Neurosurgery, Iwate Medical University, 19-1 Uchimaru, Morioka, 020-8505. Japan. ootawara-nsu@umin.ac.jp
authors.forename: Yasunari
authors.initials: Y
authors.lastname: Otawara
authors.forename: Kuniaki
authors.initials: K
authors.lastname: Ogasawara
authors.forename: Akira
authors.initials: A
authors.lastname: Ogawa
authors.forename: Keiko
authors.initials: K
authors.lastname: Yamadate
mesh_terms: D000328:Adult; D000368:Aged; D002540:Cerebral Cortex / Q000098:blood supply; D003071:Cognition; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012039:Regional Blood Flow; D016896:Treatment Outcome