[Blood coagulation parameters in patients with lichen planus].
The aim of this study was to evaluate some blood parameters of coagulation process in blood plasma of patients suffering from lichen planus. The study group consisted of 23 patients--14 women and 9 men, aged 33-75 years. Control group contained 30-age matched healthy persons. In blood of plasma the following parameters were determined: activity of antithrombin III (AT III) and concentration of prothrombin fragments 1+2 (F1+2), complexes thrombin-antithrombin III (TAT). In blood plasma of patients with lichen planus the concentration of F1+2 was significantly higher than in healthy persons. Increased concentration of F1+2 indicated intensive thrombinogenesis in vivo in patients with lichen planus.
Wankiewicz
Anna
A
Katedra i Klinika Dermatologii AM w Bydgoszczy.
Iwan-Zietek
Iza
I
Rość
Danuta
D
D000328:Adult; D000368:Aged; D000990:Antithrombin III / Q000378:metabolism*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008010:Lichen Planus / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011516:Prothrombin / Q000378:metabolism*
D000990:Antithrombin III; D011516:Prothrombin