Phytochemical constituents of Carpesium macrocephalum F(R). et S(AV).
From the methanol extract of the whole plants of Carpesium macrocephalum F(R). et S(AV)., five sesquiterpene lactones (1: carabron, 2: tomentosin, 3: ivalin, 4: 4H-tomentosin, 5: carabrol) and three terpenoids (6: loliolide, 7: vomifoliol, 8: citrusin C) were isolated. The structures and stereochemistry of compounds 1-8 were established on the basis of chemical analysis as well as 1D- and 2D-NMR spectroscopy. Among them, compounds 2, 4, and 6-8 were isolated for the first time from Carpesium species.
Kim
Mi-Ran
MR
College of Pharmacy, Chungbuk National University, Cheongju 361-763, Korea.
Lee
Seung-Kyu
SK
Kim
Chang-Soo
CS
Kim
Kyung-Soon
KS
Moon
Dong-Cheul
DC
D019659:Asteraceae / Q000737:chemistry*; D002725:Chloroform; D006586:Hexanes; D007723:Korea; D009682:Magnetic Resonance Spectroscopy; D000432:Methanol; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification; D012997:Solvents; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet; D014867:Water
D006586:Hexanes; D012717:Sesquiterpenes; D012997:Solvents; D014867:Water; D002725:Chloroform; D000432:Methanol