title: Differences in autonomic responses between subjects with and without nausea while watching an irregularly oscillating video.
abstract: Prodromal signs such as cardiac rhythm disturbance and changes in gastric motility are generally induced before and during nausea in humans. These autonomic reactions were compared in subjects who were or were not experiencing nausea. Nausea was induced by having the subjects view a movie of oscillating pictures. Seventeen healthy volunteers were asked to relax their muscles and watch the movie. Electrogastrogram (EGG), electrocardiogram (ECG), palmar and metopic perspiration, digital blood flow and thoracic movement related to respiration were simultaneously measured while the subjects viewed the movie. A total of 11 of 17 subjects complained of nausea after watching the movie. The characteristic changes in their autonomic responses during exposure to the movie were as follows. The power of the EGG, heart rate and metopic perspiration significantly increased compared to those before watching the movie. The respiratory cycle gradually increased during and even after watching the movie. In contrast, no significant changes in the power of the EGG, heart rate and metopic perspiration were observed in the remaining six subjects who did not experience nausea. The role of the autonomic nervous system in nausea is discussed. These results suggest that these symptoms regarding the sympathetic nervous system could actually be defensive reactions against the sensation of nausea.
authors.affiliation: Department of Physiology, Kawasaki Medical School, Kurashiki, 701-0192, Japan. himi@med.kawasaki-m.ac.jp
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Himi
authors.forename: Tomoshige
authors.initials: T
authors.lastname: Koga
authors.forename: Emi
authors.initials: E
authors.lastname: Nakamura
authors.forename: Motoi
authors.initials: M
authors.lastname: Kobashi
authors.forename: Masanobu
authors.initials: M
authors.lastname: Yamane
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Tsujioka
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001341:Autonomic Nervous System / Q000502:physiology*; D004562:Electrocardiography / Q000379:methods; D005260:Female; D005769:Gastrointestinal Motility / Q000502:physiology; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D009041:Motion Sickness / Q000503:physiopathology*; D009325:Nausea / Q000503:physiopathology*; D013997:Time Factors; D014741:Video Recording