[Effects of prognostic parameters and radiotherapy on survival of patients with pulmonary cancer].
OBJECTIVE
To analyze factors influencing expected survival of pulmonary cancer (PC) patients given radiotherapy, i.e. age of the patient, stage of the disease, size of the tumor, involvement of the lymph nodes, a total focal dose, space distribution of the dose.


METHODS
Among PC patients 87% were males and 73.9% were 60 years of age and older. Local PC (stage IIIa and IIIb) was diagnosed in 65.2%. Non-small-cell PC was in 83.8%. Effects of radiotherapy on the survival was analysed in 115 patients. Total focal doses made up 30 Gy (3.0 Gy/10 fractions) to 70 Gy (2.0 Gy/35 fractions).


RESULTS
Longer survival was achieved after irradiation with greater dose and modern three-dimentional planning of conformic radiotherapy. A significant prolongation of the survival was seen in raising the total focal dose to 50 Gy. There is a correlation between the dose and conformity of the dose distribution. During the study 58.2% patients died.


CONCLUSIONS
Assessment of the survival of PC patients given radiotherapy has shown that negative prognostic factors are the following: PC stage IIIA, IIIB and IV, extensive local spread of the tumor, large primary tumor, involvement of the lymph nodes.
Iuozaĭtite
E
E
Inchiura
A
A
Sakalaukas
R
R
Valius
L
L
D000368:Aged; D005260:Female; D005720:Gamma Rays; D006801:Humans; D008017:Life Expectancy; D008175:Lung Neoplasms / Q000503:physiopathology / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011829:Radiation Dosage; D011879:Radiotherapy Dosage