title: [Effects of anticoagulation therapy with low molecular weight heparin in acute pancreatitis].
abstract: OBJECTIVE
  To evaluate the effects of anticoagulation therapy with low molecular weight heparin in acute pancreatitis.
  
  
  METHODS
  Low molecular weight heparin, in a dose of 40 mg or 0.01 ml/kg, by subcutaneous injection, every 12 hours, was administered to 17 acute pancreatitis patients combined with conventional therapy. The changes of serum enzymology and prognosis in patients treated with low molecular weight heparin or conventional therapy were observed.
  
  
  RESULTS
  Anticoagulation by low molecular weight heparin could significantly decrease the blood white cell count of patients with acute pancreatitis and increase their arterial blood oxygen partial pressure. It could cut down the duration of hospitalization and reduce the aggravation rate, secondary operation rate, and mortality of these patients without increasing hemorrhagic tendency or its related complications.
  
  
  CONCLUSIONS
  Anticoagulation therapy with low molecular weight heparin is safe and effective in the treatment of acute pancreatitis, and it may improve its prognosis.
authors.affiliation: 304th Division, General Hospital of PLA, Beijing 100037, China.
authors.forename: Hua-bo
authors.initials: HB
authors.lastname: Jiao
authors.forename: Zhi
authors.initials: Z
authors.lastname: Qiao
authors.forename: Xiang-long
authors.initials: XL
authors.lastname: Tan
authors.forename: Jun-dong
authors.initials: JD
authors.lastname: Du
authors.forename: Yang
authors.initials: Y
authors.lastname: Fei
authors.forename: Da-dong
authors.initials: DD
authors.lastname: Wang
authors.forename: Ji-ye
authors.initials: JY
authors.lastname: Li
authors.forename: Yong-ming
authors.initials: YM
authors.lastname: Yao
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use*; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000188:drug therapy*; D011379:Prognosis
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight