title: [Topical application of morphine gel in inflammatory mucosal and cutaneous lesions].
abstract: OBJECTIVE
  The aim of this study was to demonstrate a peripheral local opioid effect using case examples involving inflammatory mucosal and cutaneous lesions.
  
  
  METHODS
  A 0.1% morphine gel, mixed in the hospital pharmacy, was applied several times daily to inflammatory mucosal lesions (oral, anogenital and in one patient to a skin ulcer). The effects and side effects were documented.
  
  
  RESULTS
  All patients experienced a significant reduction in pain with the use of topical morphine gel and no side effects were seen.
  
  
  CONCLUSIONS
  Topical peripheral application of morphine gel is a simple, effective method that can be carried out by patients several times a day with few side effects.
authors.affiliation: Abteilung für Anästhesiologie und allgemeine Intensivmedizin, LKH Klagenfurt.
authors.forename: M
authors.initials: M
authors.lastname: Platzer
authors.forename: R
authors.initials: R
authors.lastname: Likar
authors.forename: C
authors.initials: C
authors.lastname: Stein
authors.forename: E
authors.initials: E
authors.lastname: Beubler
authors.forename: R
authors.initials: R
authors.lastname: Sittl
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage* / Q000627:therapeutic use*; D009092:Mucous Membrane / Q000187:drug effects / Q000473:pathology; D012871:Skin Diseases / Q000503:physiopathology*; D012883:Skin Ulcer / Q000503:physiopathology*
chemical_list: D000701:Analgesics, Opioid; D009020:Morphine