title: A comparison of anesthetic quality in propofol-spinal anesthesia and propofol-fentanyl anesthesia for total knee arthroplasty in elderly patients.
abstract: OBJECTIVE
  To compare propofol plus spinal anesthesia during spontaneous ventilation using the Laryngeal Mask Airway and propofol plus fentanyl anesthesia during mechanical ventilation with an endotracheal tube on quality of recovery after anesthesia.
  
  
  METHODS
  Prospective, randomized study.
  
  
  METHODS
  Hirosaki National Hospital.
  
  
  METHODS
  150 patients (aged > 70 years) undergoing total knee arthroplasty.
  
  
  METHODS
  Patients were divided randomly into two groups, to receive spontaneous ventilation with a Laryngeal Mask Airway during propofol-spinal anesthesia, or to receive propofol-fentanyl anesthesia with mechanical ventilation via endotracheal tube.
  
  
  METHODS
  Quality of anesthesia recovery such as nausea, vomiting, headache, pain throat, hoarse voice, back pain, dizziness, feeling comfortable, dreaming, recovery times in recovery of anesthesia, recovery times, postoperative pain, confusion, was assessed.
  
  
  RESULTS
  The frequency of postoperative pain throat, hoarse voice, and nausea was significantly lower in the propofol-spinal anesthesia group than the propofol-fentanyl anesthesia group. The time to extubation, emergence, response to commands, and orientation were significantly faster (p < 0.001) in the propofol-spinal anesthesia group than the propofol-fentanyl anesthesia group. The frequency of postoperative confusion occurring in the propofol-spinal anesthesia group during the first 24 hours was significantly lower than that of the propofol-fentanyl anesthesia group (p = 0.03).
  
  
  CONCLUSIONS
  Propofol-spinal anesthesia provided better and faster recovery than did propofol-fentanyl anesthesia for elderly patients undergoing total knee arthroplasty.
authors.affiliation: Department of Anesthesiology, Hirosaki National Hospital, Hirosaki, Japan. masuika@cc.hirosaki-u.ac.jp
authors.forename: Akira
authors.initials: A
authors.lastname: Kudoh
authors.forename: Hajime
authors.initials: H
authors.lastname: Takase
authors.forename: Tomoko
authors.initials: T
authors.lastname: Takazawa
mesh_terms: D000368:Aged; D000762:Anesthesia Recovery Period; D000775:Anesthesia, Spinal; D019162:Anesthetics, Combined / Q000008:administration & dosage* / Q000009:adverse effects; D018686:Anesthetics, Intravenous / Q000008:administration & dosage* / Q000009:adverse effects; D019645:Arthroplasty, Replacement, Knee; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007442:Intubation, Intratracheal / Q000379:methods; D008297:Male; D015742:Propofol / Q000008:administration & dosage* / Q000009:adverse effects; D012121:Respiration, Artificial
chemical_list: D019162:Anesthetics, Combined; D018686:Anesthetics, Intravenous; D005283:Fentanyl; D015742:Propofol