title: VanE-type vancomycin-resistant Enterococcus faecalis clinical isolates from Australia.
abstract: Three distinct Enterococcus faecalis VanE-type isolates-BM4574, BM4575, and BM4576-obtained in Australia were studied. Expression of the resistance genes was constitutive in BM4575, probably due to a 2-bp deletion into the vanSE gene, and inducible in BM4574 and BM4576. Transcription analysis of the vanE operons suggested that the five genes were cotranscribed from an initiation site located 25 bp upstream from the ATG start codon of vanE.
authors.affiliation: Unité des Agents Antibactériens, Institut Pasteur, Paris, France.
authors.forename: Lorena
authors.initials: L
authors.lastname: Abadía-Patiño
authors.forename: Keryn
authors.initials: K
authors.lastname: Christiansen
authors.forename: Jan
authors.initials: J
authors.lastname: Bell
authors.forename: Patrice
authors.initials: P
authors.lastname: Courvalin
authors.forename: Bruno
authors.initials: B
authors.lastname: Périchon
mesh_terms: D001315:Australia; D001426:Bacterial Proteins / Q000235:genetics*; D002874:Chromosome Mapping; D003062:Codon / Q000235:genetics; D017931:DNA Primers; D016521:Electrophoresis, Gel, Pulsed-Field; D013293:Enterococcus faecalis / Q000187:drug effects* / Q000201:enzymology; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology*; D008025:Ligases / Q000235:genetics*; D009876:Operon / Q000235:genetics; D010457:Peptidoglycan / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014158:Transcription, Genetic; D020713:Vancomycin Resistance / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; D003062:Codon; D017931:DNA Primers; D010457:Peptidoglycan; D008025:Ligases; C469907:VanE protein, Enterococcus faecalis