[Polymorphic analysis of four Y short tandem repeat loci in Han nationality of Hebei province in China].
OBJECTIVE
To investigate the distribution of the polymorphism of the Y-chromosomal loci DYS438, DYS439, GATA A7.1 and GATA A7.2 among Han population in Hebei province.


METHODS
With the use of PCR followed by polyacrylamide gel electrophoresis and silver staining, the allele frequencies of these loci in 164 unrelated men of Han population were investigated.


RESULTS
Four, five, five, four alleles were observed at the loci DYS438, DYS439, GATA A7.1 and GATA A7.2 respectively; the frequencies of these alleles ranged from 0.0359 to 0.6587, from 0.0179 to 0.4107, from 0.0122 to 0.4146 and from 0.0476 to 0.5238 respectively; the probability discrimination of these loci were 0.5121, 0.6811, 0.6679 and 0.6327 respectively. Seventy different haplotypes were found at these loci. Thirty-six different haplotypes appeared only once. The power of discrimination of these four loci was 0.9480.


CONCLUSIONS
The results demonstrate that these loci(DYS438, DYS439, GATA A7.1 and GATA A7.2) are good genetic markers with high determination power and can be applied to individual identification, especially in paternity test and the detection of mixed samples.
Zhao
Li
L
Department of Forensic Medicine, Hebei Medical University, Shijiazhuang, Hebei, 050017 P. R. China.
Yao
Yu-xia
YX
Cong
Bin
B
Fu
Li-hong
LH
Gu
Zhen-yong
ZY
Li
Shu-jin
SJ
Zuo
Min
M
Zhang
Guo-zhong
GZ
D000483:Alleles; D044466:Asian People / Q000235:genetics*; D002681:China / Q000208:ethnology; D041322:Chromosomes, Human, Y; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D005838:Genotype; D006239:Haplotypes; D006801:Humans; D008297:Male; D010334:Paternity; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences / Q000235:genetics*
D005819:Genetic Markers