title: The role of infrapopliteal angioplasty.
abstract: Infrapopliteal percutaneous transluminal angioplasty (PTA) is currently indicated in patients with critical limb ischaemia (CLI). It may be performed after femoral angioplasty or bypass surgery, to improve outflow and hence patency of the proximally treated segment. Patients with CLI are typically elderly with multiple co-morbidities and limited life expectancy and therefore, a procedure, which is minimally invasive with reduced morbidity and mortality but lesser long-term patency, may be more appropriate than a more invasive procedure with better long-term patency. Clinical success is superior to angiographic patency, because once healing has occurred, should the artery restenose or occlude, collateral flow can be sufficient to preserve tissue integrity if there is no further injury. Although no prospective randomized trials have been performed, the reported limb-salvage rates of PTA are comparable with surgery. As PTA carries a lower morbidity and mortality, shorter hospital stay and does not preclude surgery, it is ideal for this group of patients who are high-risk surgical candidates. Improvements in guide-wire and catheter technology and recanalization techniques mean that very long stenoses or occlusions, and multiple lesions can be treated successfully. At the current time, PTA is the treatment of choice for infrapopliteal occlusive disease; experience with the use of stents in this territory is increasing but currently insufficient to justify their primary use.
authors.affiliation: Department of Radiology, St George's Hospital, Blackshaw Road, London SW17 0QT, UK.
authors.forename: D
authors.initials: D
authors.lastname: Tsetis
authors.forename: A-M
authors.initials: AM
authors.lastname: Belli
mesh_terms: D000800:Angioplasty, Balloon / Q000009:adverse effects / Q000379:methods*; D001157:Arterial Occlusive Diseases / Q000601:surgery*; D016638:Critical Illness; D004343:Drug Implants; D006801:Humans; D007383:Intermittent Claudication / Q000601:surgery; D007511:Ischemia / Q000628:therapy*; D053685:Laser Therapy / Q000379:methods; D007866:Leg / Q000098:blood supply*; D023821:Limb Salvage / Q000379:methods; D011150:Popliteal Artery; D015607:Stents; D014464:Ultrasonic Therapy / Q000379:methods
chemical_list: D004343:Drug Implants