title: [Characterization of the foci of meningococcal infection in closed groups of males].
abstract: A total of 257 foci of meningococcal infection in groups of servicemen were selectively examined in 1982-2002. From these groups 353 patients with generalized forms of the disease underwent hospitalization. Most of the foci had a single infection, the proportion of foci with 10-40 patients was 82.6%. The meningococcal infection rate among humans in the foci was 25-37%, group A meningococci playing the leading role. In the structure of meningococcal infection generalized forms of infection constituted 16%, localized forms constituted 25% and inapparent forms (carriers)--59%. The formation of the morbidity structure was influenced by the type of the focus (with a single or multiple infection) and the character of morbidity for many years (during epidemic or at the period between epidemics). No absolute dependence of the level of meningococcal carrier state in the groups of servicemen on the appearance of the generalized forms of meningococcal infection was noted. Thus, both during epidemic and at the period between epidemics the population of meningococci, heterogeneous in its serological structure and differing in its clinical and epidemiological importance, constantly circulated with the leading role played by group A meningococci.
authors.forename: M V
authors.initials: MV
authors.lastname: Makhnev
authors.forename: A V
authors.initials: AV
authors.lastname: Makhnev
mesh_terms: D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology; D004196:Disease Outbreaks; D004197:Disease Reservoirs; D006801:Humans; D008297:Male; D008589:Meningococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D008889:Military Personnel; D009345:Neisseria meningitidis / Q000145:classification / Q000302:isolation & purification*; D012426:Russia / Q000453:epidemiology; D012703:Serotyping