title: Triterpenoid saponins from leaves of Hedera pastuchowii.
abstract: Five new triterpenoid saponins, pastuchoside A (1), B (3), C (5), D (7) and E (9), were isolated from the leaves of Hedera pastuchowii. They have oleanolic acid or hederagenin as aglycone. The structures were established by NMR spectroscopy including gs (gradient selected)-COSY, gs-HSQC, gs-HSQC-TOCSY and gs-HMBC experiments, and mass spectrometry (ESI-HR-MS). Heptaoside saponins, compounds 1 and 3, are described for the first time in the genus Hedera.
authors.affiliation: Institute of Pharmacochemistry, Academy of Sciences of Georgia, Tbilisi, Georgia.
authors.forename: Vakhtang
authors.initials: V
authors.lastname: Mshvildadze
authors.forename: Riad
authors.initials: R
authors.lastname: Elias
authors.forename: Robert
authors.initials: R
authors.lastname: Faure
authors.forename: David
authors.initials: D
authors.lastname: Rondeau
authors.forename: Laurent
authors.initials: L
authors.lastname: Debrauwer
authors.forename: Genri
authors.initials: G
authors.lastname: Dekanosidze
authors.forename: Ether
authors.initials: E
authors.lastname: Kemertelidze
authors.forename: Guy
authors.initials: G
authors.lastname: Balansard
mesh_terms: D035981:Hedera / Q000737:chemistry*; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D018515:Plant Leaves / Q000737:chemistry; D012503:Saponins / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D014315:Triterpenes / Q000737:chemistry*
chemical_list: D012503:Saponins; D014315:Triterpenes; C499799:pastuchoside A; C499801:pastuchoside B; C499800:pastuchoside C; C499802:pastuchoside D