[Vascular endothelial cells and osteoblasts].
Bone has a variety of cells including osteoblasts and vascular endothelial cells. Evidence for interaction between these cells in bone has been accumulated. In this review, roles of vascular endothelial growth factor (VEGF) in bone are discussed. I refer to increase in osteoblastic VEGF production by statins, drugs for hypercholesterolemia, which possess promotion of bone formation. Moreover, I have mentioned the presence of bone-like tissue in atherosclerotic plaque.
Horiuchi
Noboru
N
Department of Biochemistry, Ohu University School of Dentistry.
D000818:Animals; D042783:Endothelial Cells / Q000502:physiology*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology; D051379:Mice; D010006:Osteoblasts / Q000502:physiology*; D042461:Vascular Endothelial Growth Factor A / Q000502:physiology
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D042461:Vascular Endothelial Growth Factor A