title: Shape-tunable polymer nodules grown from liposomes via ring-opening metathesis polymerization.
abstract: A new inisurf (acting as surfactant and initiator) molecule for ring-opening metathesis polymerization (ROMP) was synthesized and used in aqueous solution in order to control the size and shape of polymer nodules grown from liposomes. Nodules were observed to grow in size with conversion of monomer, and depending on the monomer used, they adopted either a spherical or comet-like shape. Here, we investigate polymer production from a liposome surface. We use a hydrophobic derivative of the Grubbs catalyst positioned at the liposome surface to allow for ROMP of monomers dissolved in the aqueous outer phase. We obtain nodules of polymer that can grow up to tens of micrometers, unveiling new efficient possibilities of polymerization from a membrane in an aqueous solution.
authors.affiliation: Laboratoire de Physicochimie Curie, Institut Curie, UMR 168, 11 rue Pierre et Marie Curie, 75231 Paris Cedex 05, France.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Jarroux
authors.forename: Patrick
authors.initials: P
authors.lastname: Keller
authors.forename: Anne-Françoise
authors.initials: AF
authors.lastname: Mingotaud
authors.forename: Christophe
authors.initials: C
authors.lastname: Mingotaud
authors.forename: Cécile
authors.initials: C
authors.lastname: Sykes
mesh_terms: D003500:Cyclization; D008081:Liposomes / Q000737:chemistry*; D008853:Microscopy / Q000379:methods; D009636:Norbornanes / Q000737:chemistry*; D010713:Phosphatidylcholines / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*
chemical_list: D008081:Liposomes; D009636:Norbornanes; D010713:Phosphatidylcholines; D011108:Polymers; C017251:1,2-oleoylphosphatidylcholine