Serum levels of nitric oxide end products and interactions with lipoproteins in patients with coronary artery disease.
The purpose of this study was to examine whether the serum levels of nitric oxide end products and the ratio of nitrite to lipoproteins are valid instruments in the clinical follow-up of patients with coronary artery disease. 65 subjects were divided into three groups, including patients with coronary artery disease, silent coronary artery disease and controls. The serum nitrite level and also the ratio of nitrite to high-density lipoprotein were significantly different between the groups. According to the number of obstructed arteries, the serum nitrite level and the ratio of nitrite to high-density lipoprotein were found statistically different between the groups. There was a positive correlation between the serum nitrite level and the ratio of nitrite to high-density lipoprotein and the number of obstructed arteries. In conclusion, the serum nitrite level and ratio of nitrite to high-density lipoprotein may provide a beneficial guide to follow-up the status of patients with coronary artery disease.
Afrasyap
Lale
L
Department of Biochemistry, Faculty of Health, Mugla University, Istanbul, Turkey. laledr@yahoo.com
Oztürk
Güler
G
Erbaş
Deniz
D
D000368:Aged; D001024:Aortic Valve Stenosis / Q000097:blood / Q000473:pathology; D008076:Cholesterol, HDL / Q000097:blood*; D008078:Cholesterol, LDL / Q000097:blood*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000097:blood* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009566:Nitrates / Q000097:blood*; D009569:Nitric Oxide / Q000378:metabolism; D009573:Nitrites / Q000097:blood*; D012044:Regression Analysis
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D009566:Nitrates; D009573:Nitrites; D009569:Nitric Oxide