title: Associations between relationship support and psychological reactions of participants and partners to BRCA1 and BRCA2 testing in a clinic-based sample.
abstract: BACKGROUND
  Despite the potential importance of communication about genetic testing between test participants and their significant others, little is known about social support and communication between women undergoing BRCA1 and BRCA2 testing and their partners.
  
  
  OBJECTIVE
  The aims of this longitudinal study were to examine communication about genetic testing during and following testing and to evaluate whether communication is associated with psychological distress reported by test participants and their partners.
  
  
  METHODS
  Participants were 153 women who were undergoing genetic testing and 118 partners of women undergoing testing. Relationship communication and distress were evaluated at the time of pretest education and 6 months postdisclosure.
  
  
  RESULTS
  Overall, the decision to undergo testing was discussed by the majority of test participants and partners, and most couples felt their partners were supportive. Most women disclosed their results to their partners. Longitudinal analyses suggested that less support and protective buffering were associated with greater distress 6 months postdisclosure among test participants, whereas lower comfort in sharing concerns and partner support were associated with lower distress 6 months postdisclosure among partners.
  
  
  CONCLUSIONS
  The results of this study suggest that the majority of couples respond supportively during the test experience, but for a small subset of couples the process can strain the relationship. Partner support during this process is important, particularly for test participants dealing with an uninformative test result.
authors.affiliation: Fox Chase Cancer Center, Philadelphia, PA 19111, USA. SL_Manne@fccc.edu
authors.forename: Sharon
authors.initials: S
authors.lastname: Manne
authors.forename: Janet
authors.initials: J
authors.lastname: Audrain
authors.forename: Marc
authors.initials: M
authors.lastname: Schwartz
authors.forename: David
authors.initials: D
authors.lastname: Main
authors.forename: Clinton
authors.initials: C
authors.lastname: Finch
authors.forename: Caryn
authors.initials: C
authors.lastname: Lerman
mesh_terms: D000554:Ambulatory Care Facilities; D001943:Breast Neoplasms / Q000235:genetics / Q000523:psychology*; D003142:Communication; D005260:Female; D019398:Genes, BRCA1; D024522:Genes, BRCA2; D005817:Genetic Counseling; D005820:Genetic Testing / Q000523:psychology*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012044:Regression Analysis; D018454:Spouses / Q000523:psychology*; D013315:Stress, Psychological; D014481:United States