title: [Comparison of hepatic protein synthesis function between Banna Minipig Inbred Line and human].
abstract: OBJECTIVE
  This is a research aimed at comparing the hepatic protein synthesis function of Banna Minipig Inbred Line (BMI) with that of human so as to evaluate the possibility of porcine liver replacement of human counterpart.
  
  
  METHODS
  The venous blood samples from BMI and volunteer participants were collected. The albumin and total protein in the separated sera were tested using Beckman delta CX7 autoanalyzer, and serum protein electrophoresis was performed.
  
  
  RESULTS
  No significant differences in albumin and in the percentage and concentration of globulins synthesized in liver (alpha1-, alpha2- and beta-globulin) between BMI and human were observed. The percentage and concentration of gamma-globulin synthesized in the lymphocytes of BMI were significantly higher than those of human.
  
  
  CONCLUSIONS
  The above findings suggested the similarity between BMI liver and human liver in respect to albumin and alpha, beta-globulin synthesis.
authors.affiliation: Lab of Transplant Engineering and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
authors.forename: You-ping
authors.initials: YP
authors.lastname: Li
authors.forename: Jing-qiu
authors.initials: JQ
authors.lastname: Cheng
authors.forename: Zhi-ying
authors.initials: ZY
authors.lastname: Peng
authors.forename: Sheng-fu
authors.initials: SF
authors.lastname: Li
authors.forename: Yang-zhi
authors.initials: YZ
authors.lastname: Zeng
mesh_terms: D000510:Alpha-Globulins / Q000032:analysis / Q000302:isolation & purification; D000818:Animals; D017849:Animals, Inbred Strains; D001609:Beta-Globulins / Q000032:analysis / Q000302:isolation & purification; D001798:Blood Proteins / Q000032:analysis*; D004586:Electrophoresis / Q000379:methods; D006801:Humans; D008099:Liver / Q000378:metabolism*; D016031:Liver Transplantation; D008297:Male; D014176:Protein Biosynthesis; D013552:Swine; D013556:Swine, Miniature; D014183:Transplantation, Heterologous; D005719:gamma-Globulins / Q000032:analysis / Q000302:isolation & purification
chemical_list: D000510:Alpha-Globulins; D001609:Beta-Globulins; D001798:Blood Proteins; D005719:gamma-Globulins