[Functional neuroanatomy of emotions].
OBJECTIVE
In the present study, functional neuroanatomy of the frontal lobe and limbic system could be uncovered as emotion processing neural substrates. fMRI was used to test the influence of induced emotions on a non-affective, attention-demanding, cognitive task.


METHODS
6 Psychopaths versus 7 controls were analyzed by fMRI with a simon-paradigm after emotion induction.


RESULTS
Emotion induction differentially influenced cortical activation patterns in emotion related brain areas like the amygdala and the medial prefrontal cortex.


CONCLUSIONS
Structural-morphological neural areas of emotion regulation in "psychopathy" show variant activation patterns in fMRI. The neural basis of emotional impairment could be a dysfunctional medial prefrontal cortex and amygdala.
Schwerdtner
Johannes
J
Klinik und Poliklinik für Psychiatrie und Psychotherapie der Universität Regensburg. johannes.schwerdtner@medbo.de
Sommer
Monika
M
Weber
Tatjana
T
Müller
Jürgen
J
D000328:Adult; D000339:Affect / Q000502:physiology*; D000679:Amygdala / Q000503:physiopathology; D000987:Antisocial Personality Disorder / Q000503:physiopathology*; D001143:Arousal / Q000502:physiology; D001288:Attention / Q000502:physiology*; D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping; D004193:Discrimination Learning; D004644:Emotions / Q000502:physiology*; D005555:Forensic Psychiatry; D005625:Frontal Lobe / Q000503:physiopathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008032:Limbic System / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D009415:Nerve Net / Q000503:physiopathology; D010364:Pattern Recognition, Visual / Q000502:physiology*; D017397:Prefrontal Cortex / Q000503:physiopathology; D012016:Reference Values