New sesquiterpenes from Pluchea arabica.
Two new sesquiterpenes, godotol A (1) and godotol B (2), were isolated from Pluchea arabica. Their structures were determined by analysis of NMR data. The absolute configurations of 1 and 2 were established by Mosher ester methodology. The godotols displayed weak activity against bacteria and the brine shrimp larvae. They were also inactive in the DPPH antioxidant assay.
Fatope
Majekodunmi O
MO
Department of Chemistry, College of Science, Sultan Qaboos University, PO Box 36, Postal Code 123, Al-Khod, Muscat, Sultanate of Oman. majek@squ.edu.om
Nair
Rani S
RS
Marwah
Ruchi G
RG
Al-Nadhiri
Haifaa H S
HH
D000818:Animals; D001156:Artemia / Q000187:drug effects; D019659:Asteraceae / Q000737:chemistry*; D001713:Biphenyl Compounds; D002176:Candida albicans / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D007711:Klebsiella pneumoniae / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009850:Oman; D010851:Picrates / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012476:Salmonella arizonae / Q000187:drug effects; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects
D001713:Biphenyl Compounds; D010851:Picrates; D012717:Sesquiterpenes; C495020:godotol A; C495021:godotol B; C004931:1,1-diphenyl-2-picrylhydrazyl