Structure confirmation of a bioactive lactone isolated from Otoba parvifolia through the synthesis of a model compound.
Synthesis of a model compound 4 structurally related to a bioactive lactone 3 isolated from Otoba parvifolia has been accomplished. The good match between the NMR data of both compounds suggests they have identical bicyclic [3.3.1] carbon skeletons.
Marques
Francisco A
FA
Chemistry Department, Federal University of Paraná, P.O. Box 19081, Curitiba, PR, 81.531-990 Brazil. tic@ufpr.br
Lenz
Cesar A
CA
Simonelli
Fabio
F
Maia
Beatriz Helena L Noronha Sales
BH
Vellasco
Adriana P
AP
Eberlin
Marcos N
MN
D005638:Fruit / Q000737:chemistry; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008958:Models, Molecular; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*
D007783:Lactones