A stereodivergent synthesis of virantmycin by an enzyme-mediated diester desymmetrization and a highly hindered aryl amination.
Back
Thomas G
TG
Department of Chemistry, University of Calgary, Calgary, AB, T2N 1N4, Canada. tgback@ucalgary.ca
Wulff
Jeremy E
JE
D000586:Amination; D000818:Animals; D004950:Esterases / Q000378:metabolism*; D004952:Esters / Q000737:chemistry* / Q000378:metabolism*; D005459:Fluorides / Q000737:chemistry; D008099:Liver / Q000201:enzymology; D015394:Molecular Structure; D011804:Quinolines / Q000737:chemistry* / Q000378:metabolism*; D013237:Stereoisomerism; D013552:Swine
D004952:Esters; D011804:Quinolines; C030886:virantmycin; D004950:Esterases; D005459:Fluorides