Stroke after varicella vaccination.
Two children presented with acute hemiparesis 5 days and 3 weeks following varicella vaccination. Both showed unilateral infarction of the basal ganglia and internal capsule, a distribution consistent with varicella angiopathy. Both children had small patent foramen ovale (PFO), and one child also had severe iron-deficiency anemia, which may have predisposed the patient to this adverse effect.
Wirrell
Elaine
E
Division of Pediatric Neurology, Alberta Children's Hospital, and the University of Calgary, Ontario, Canada. wirrell@calgaryhealthregion.ca
Hill
Michael D
MD
Jadavji
Taj
T
Kirton
Adam
A
Barlow
Karen
K
D019433:Chickenpox Vaccine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007223:Infant; D010291:Paresis / Q000139:chemically induced* / Q000503:physiopathology; D020521:Stroke / Q000139:chemically induced*
D019433:Chickenpox Vaccine