Nuclear pore complex structure: unplugged and dynamic pores.
Nuclear pore complexes (NPCs) are large protein assemblies embedded in the nuclear envelope that act as passageways for transport of molecules into and out of the nucleus. Two new studies, one in Nature Cell Biology and one in Science , offer direct evidence that the NPC is a highly dynamic structure.
Panté
Nelly
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Department of Zoology, University of British Columbia, 6270 University Boulevard, Vancouver, British Columbia V6T 1Z4, Canada.
D000818:Animals; D016880:Anisotropy; D002467:Cell Nucleus / Q000378:metabolism / Q000648:ultrastructure; D003593:Cytoplasm / Q000378:metabolism; D004023:Dictyostelium; D049452:Green Fluorescent Proteins / Q000378:metabolism; D006801:Humans; D008854:Microscopy, Electron; D008954:Models, Biological; D022022:Nuclear Pore / Q000502:physiology*; D028861:Nuclear Pore Complex Proteins / Q000737:chemistry* / Q000378:metabolism
D028861:Nuclear Pore Complex Proteins; D049452:Green Fluorescent Proteins