title: Sudden death in young adults: a 25-year review of autopsies in military recruits.
abstract: BACKGROUND
  Sudden death among military recruits is a rare but devastating occurrence. Because extensive medical data are available on this cross-sectional and diverse population, identification of the underlying causes of sudden death may promote health care policy to reduce the incidence of sudden death.
  
  
  OBJECTIVE
  To determine the causes of nontraumatic sudden death among a cohort of military recruits.
  
  
  METHODS
  Retrospective cohort study using demographic and autopsy data from the Department of Defense Recruit Mortality Registry.
  
  
  METHODS
  Basic military training.
  
  
  METHODS
  All nontraumatic sudden deaths from a monitored 6.3 million men and women age 18 to 35 years.
  
  
  METHODS
  Descriptive analysis, crude mortality rates of causes of sudden death, and frequency of events as a function of cause of death.
  
  
  RESULTS
  Of 126 nontraumatic sudden deaths (rate, 13.0/100,000 recruit-years), 108 (86%) were related to exercise. The most common cause of sudden death was an identifiable cardiac abnormality (64 of 126 recruits [51%]); however, a substantial number of deaths remained unexplained (44 of 126 recruits [35%]). The predominant structural cardiac abnormalities were coronary artery abnormalities (39 of 64 recruits [61%]), myocarditis (13 of 64 recruits [20%]), and hypertrophic cardiomyopathy (8 of 64 recruits [13%]). An anomalous coronary artery accounted for one third (21 of 64 recruits) of the cases in this cohort, and, in each, the left coronary artery arose from the right (anterior) sinus of Valsalva, coursing between the pulmonary artery and aorta.
  
  
  CONCLUSIONS
  This cohort underwent a preenlistment screening program that included history and physical examination; this may have altered outcomes.
  
  
  CONCLUSIONS
  Cardiac abnormalities are the leading identifiable cause of sudden death among military recruits; however, more than one third of sudden deaths remain unexplained after detailed medical investigation.
authors.affiliation: Brooke Army Medical Center, San Antonio, Texas, USA. Robert.Eckart@us.army.mil
authors.forename: Robert E
authors.initials: RE
authors.lastname: Eckart
authors.forename: Stephanie L
authors.initials: SL
authors.lastname: Scoville
authors.forename: Charles L
authors.initials: CL
authors.lastname: Campbell
authors.forename: Eric A
authors.initials: EA
authors.lastname: Shry
authors.forename: Karl C
authors.initials: KC
authors.lastname: Stajduhar
authors.forename: Robert N
authors.initials: RN
authors.lastname: Potter
authors.forename: Lisa A
authors.initials: LA
authors.lastname: Pearse
authors.forename: Renu
authors.initials: R
authors.lastname: Virmani
mesh_terms: D000293:Adolescent; D000328:Adult; D009202:Cardiomyopathies / Q000401:mortality; D002423:Cause of Death; D015331:Cohort Studies; D003330:Coronary Vessel Anomalies / Q000401:mortality; D003645:Death, Sudden / Q000209:etiology* / Q000517:prevention & control; D016757:Death, Sudden, Cardiac / Q000209:etiology / Q000517:prevention & control; D005260:Female; D006801:Humans; D008297:Male; D008889:Military Personnel; D012189:Retrospective Studies