title: Secondary erythrocytosis associated with distal renal tubular acidosis.
abstract: OBJECTIVE
  Diagnosis and classification of renal tubular acidosis (RTA) have traditionally been made on the basis of functional studies. Despite recent expanding knowledge about the molecular abnormalities involved in renal bicarbonate (HCO3-) and H+ transport, the pathophysiology of secondary erythrocytosis in association with distal RTA remains obscure.
  
  
  METHODS
  A 2-month-old boy with severe hyperchloremic metabolic acidosis with positive urine anion gap was diagnosed with distal RTA. Replacement therapy with sodium bicarbonate and potassium citrate succeeded in improving his metabolic acidosis and growth. His renal function remained normal. He had persistent erythrocytosis.
  
  
  CONCLUSIONS
  Secondary erythrocytosis is a rarely reported association of distal RTA. It may increase the risk of thromboembolism.
authors.affiliation: Department of Pediatrics, Saiseikai Toyama Hospital, Toyama, Japan. stingray19659@hotmail.com
authors.forename: H
authors.initials: H
authors.lastname: Matsukura
authors.forename: H
authors.initials: H
authors.lastname: Satoh
authors.forename: M
authors.initials: M
authors.lastname: Arai
authors.forename: A
authors.initials: A
authors.lastname: Higuchi
authors.forename: T
authors.initials: T
authors.lastname: Miyawaki
authors.forename: K
authors.initials: K
authors.lastname: Izumino
mesh_terms: D000141:Acidosis, Renal Tubular / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D007223:Infant; D008297:Male; D011086:Polycythemia / Q000000981:diagnostic imaging / Q000209:etiology*; D011859:Radiography