title: Benzodiazepine dependence.
abstract: BACKGROUND
  Benzodiazepine dependency can occur as a result of treatment for anxiety disorders or sleep disturbance. While benzodiazepine withdrawal can be challenging, cessation of use can be even more difficult if there are other comorbidities such as oestrogen deficiency with vasomotor symptoms and anxiety disorders.
  
  
  OBJECTIVE
  This article provides practical information for general practitioners in the management of patients with benzodiazepine dependence.
  
  
  CONCLUSIONS
  Some patients may have common medical presentations and coexisting drug dependence. It is often difficult to separate these two issues. In the case of benzodiazepine dependence, gradual withdrawal over time and nonpharmacological treatment of the symptoms of withdrawal such as anxiety or insomnia is effective. Better outcomes are achieved where the GP discusses and plans strategies well in advance with the patient. Treatment often involves multiple interventions from various health professionals. General practitioners are ideally placed to coordinate such treatment.
authors.affiliation: Drug and Alcohol Office, Centre for Postgraduate Medicine, Edith Cowan University. eric.khong@health.wa.gov.au
authors.forename: Eric
authors.initials: E
authors.lastname: Khong
authors.forename: Moira G
authors.initials: MG
authors.lastname: Sim
authors.forename: Gary
authors.initials: G
authors.lastname: Hulse
mesh_terms: D014151:Anti-Anxiety Agents / Q000009:adverse effects*; D001008:Anxiety Disorders / Q000150:complications / Q000628:therapy; D001569:Benzodiazepines / Q000009:adverse effects*; D002985:Clinical Protocols; D004361:Drug Tolerance; D005194:Family Practice / Q000379:methods; D005260:Female; D006801:Humans; D008875:Middle Aged; D010076:Oxazepam / Q000627:therapeutic use; D012064:Relaxation Therapy; D007319:Sleep Initiation and Maintenance Disorders / Q000209:etiology / Q000628:therapy; D013375:Substance Withdrawal Syndrome / Q000628:therapy*; D019966:Substance-Related Disorders / Q000175:diagnosis* / Q000628:therapy*
chemical_list: D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D010076:Oxazepam