title: [SPECT imaging of cerebral arteriovenous angiomas. A preliminary report].
abstract: OBJECTIVE
  The purpose of this study was to demonstrate scintigraphic evaluation of cerebral perfusion in patients with intracranial hemangiomas.
  
  
  METHODS
  The examination was carried out in 12 patients aged from 12 to 67 years. In all the patients cerebral angiomas were previously diagnosed and all of them were qualified for intravascular embolization. Brain scintigraphy was performed after IV injection of 99mTcECD and included the dynamic phase with images obtained every 2 seconds for 1.5 minutes and SPECT imaging. The semiquantitative analysis of regional cerebral blood flow was based on the comparison between activity in two symmetrical regions of interest. Cerebral angiography combined with intravascular embolization followed the scintigraphic examination.
  
  
  RESULTS
  Based on angiograms, the size of the nidus was estimated at 1.0 to 9.0 cm. In 8 patients the dynamic study showed an increased tracer accumulation in the region of angioma. On SPECT images the nidus was visualized as focally decreased perfusion in all cases. A decreased tracer accumulation in the area adjacent to the nidus was detected in 8 patients. The ratio of activity in the region of angioma to activity in normally perfused tissue calculated using the semiquantitative analysis was 52% to 89%.
  
  
  CONCLUSIONS
  SPECT images and dynamic phase of cerebral perfusion scintigraphy allow perfusion changes caused by the presence of intracranial angiomas to be identified.
authors.affiliation: Katedra i Zakład Medycyny Nuklearnej, Akademia Medyczna w Lublinie, Lublin, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Nocuń
authors.forename: Maciej
authors.initials: M
authors.lastname: Szajner
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Gil
authors.forename: Witold
authors.initials: W
authors.lastname: Cholewiński
authors.forename: Tomasz
authors.initials: T
authors.lastname: Trojanowski
authors.forename: Janina
authors.initials: J
authors.lastname: Zaorska-Rajca
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D002648:Child; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D015899:Tomography, Emission-Computed, Single-Photon