title: Versatile synthesis of Boc protected hydrazinoacetic acid and its application to the chemoselective ligation of TASP molecules.
abstract: This paper describes a convenient synthesis of protected hydrazine derivatives, i.e. 1,2-bis-Boc-hydrazinoacetic acid, and its application for hydrazone ligation techniques in convergent template assembled synthetic protein (TASP) synthesis.
authors.affiliation: Institute of Chemical Sciences and Engineering, Federal Institute of Technology Lausanne, CH-1015 Lausanne, Switzerland.
authors.forename: Damiano
authors.initials: D
authors.lastname: Banfi
authors.forename: Manfred
authors.initials: M
authors.lastname: Mutter
authors.forename: Luc
authors.initials: L
authors.lastname: Patiny
mesh_terms: D005998:Glycine / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000378:metabolism; D010446:Peptide Fragments / Q000138:chemical synthesis* / Q000378:metabolism
chemical_list: D010446:Peptide Fragments; C063864:hydrazinoacetic acid; D005998:Glycine