title: Listeria monocytogenes sigmaB contributes to invasion of human intestinal epithelial cells.
abstract: The role of sigma(B) in Listeria monocytogenes infection of human intestinal epithelial cells was investigated. Invasion defects associated with loss of sigma(B) paralleled those of a DeltainlA strain independently of the sigma(B)-dependent P2(prfA) promoter. Concomitantly, amounts of inlA transcript and InlA protein were significantly decreased in the DeltasigB strain.
authors.affiliation: Department of Microbiology and Immunology, VMC 5-169, Cornell University, Ithaca, NY 14853, USA.
authors.forename: Heesun
authors.initials: H
authors.lastname: Kim
authors.forename: Kathryn J
authors.initials: KJ
authors.lastname: Boor
authors.forename: Hélène
authors.initials: H
authors.lastname: Marquis
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000502:physiology*; D006801:Humans; D007413:Intestinal Mucosa / Q000382:microbiology*; D008089:Listeria monocytogenes / Q000472:pathogenicity*; D012333:RNA, Messenger / Q000032:analysis; D012808:Sigma Factor / Q000502:physiology*
chemical_list: D001426:Bacterial Proteins; D012333:RNA, Messenger; C079011:SigB protein, Bacteria; D012808:Sigma Factor; C069761:internalin protein, Bacteria