title: Design of a data model for developing laboratory information management and analysis systems for protein production.
abstract: Data management has emerged as one of the central issues in the high-throughput processes of taking a protein target sequence through to a protein sample. To simplify this task, and following extensive consultation with the international structural genomics community, we describe here a model of the data related to protein production. The model is suitable for both large and small facilities for use in tracking samples, experiments, and results through the many procedures involved. The model is described in Unified Modeling Language (UML). In addition, we present relational database schemas derived from the UML. These relational schemas are already in use in a number of data management projects.
authors.affiliation: EMBL Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
authors.forename: Anne
authors.initials: A
authors.lastname: Pajon
authors.forename: John
authors.initials: J
authors.lastname: Ionides
authors.forename: Jon
authors.initials: J
authors.lastname: Diprose
authors.forename: Joël
authors.initials: J
authors.lastname: Fillon
authors.forename: Rasmus
authors.initials: R
authors.lastname: Fogh
authors.forename: Alun W
authors.initials: AW
authors.lastname: Ashton
authors.forename: Helen
authors.initials: H
authors.lastname: Berman
authors.forename: Wayne
authors.initials: W
authors.lastname: Boucher
authors.forename: Miroslaw
authors.initials: M
authors.lastname: Cygler
authors.forename: Emeline
authors.initials: E
authors.lastname: Deleury
authors.forename: Robert
authors.initials: R
authors.lastname: Esnouf
authors.forename: Joël
authors.initials: J
authors.lastname: Janin
authors.forename: Rosalind
authors.initials: R
authors.lastname: Kim
authors.forename: Isabelle
authors.initials: I
authors.lastname: Krimm
authors.forename: Catherine L
authors.initials: CL
authors.lastname: Lawson
authors.forename: Eric
authors.initials: E
authors.lastname: Oeuillet
authors.forename: Anne
authors.initials: A
authors.lastname: Poupon
authors.forename: Stéphane
authors.initials: S
authors.lastname: Raymond
authors.forename: Tim
authors.initials: T
authors.lastname: Stevens
authors.forename: Herman
authors.initials: H
authors.lastname: van Tilbeurgh
authors.forename: John
authors.initials: J
authors.lastname: Westbrook
authors.forename: Peter
authors.initials: P
authors.lastname: Wood
authors.forename: Eldon
authors.initials: E
authors.lastname: Ulrich
authors.forename: Wim
authors.initials: W
authors.lastname: Vranken
authors.forename: Li
authors.initials: L
authors.lastname: Xueli
authors.forename: Ernest
authors.initials: E
authors.lastname: Laue
authors.forename: David I
authors.initials: DI
authors.lastname: Stuart
authors.forename: Kim
authors.initials: K
authors.lastname: Henrick
mesh_terms: D000465:Algorithms; D000595:Amino Acid Sequence; D003627:Data Interpretation, Statistical; D030562:Databases, Protein; D023281:Genomics / Q000379:methods*; D020407:Internet; D008954:Models, Biological; D011381:Programming Languages; D015202:Protein Engineering / Q000379:methods*; D011506:Proteins / Q000737:chemistry*; D040901:Proteomics / Q000379:methods*; D012106:Research; D012984:Software; D012985:Software Design; D049490:Systems Biology; D017432:Unified Medical Language System
chemical_list: D011506:Proteins