Asmarines I, J, and K and nosyberkol: four new compounds from the marine sponge Raspailia sp.
Five asmarines, the known A and F and three new ones, I, J, and K, and four diterpenes, the known chelodane, barekoxide, and zaatirin and a new one, nosyberkol, were isolated from the Nosy Be Islands (Madagascar) sponge Raspailia sp. The structures of all these compounds were established on the basis of MS and NMR data. A biogenesis for the various Raspailia sp. diterpenes is suggested.
Rudi
Amira
A
School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel-Aviv University, Ramat Aviv 69978, Israel.
Aknin
Maurice
M
Gaydou
Emile
E
Kashman
Yoel
Y
D000818:Animals; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D008270:Madagascar; D013058:Mass Spectrometry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011161:Porifera; D014407:Tumor Cells, Cultured
D004224:Diterpenes; C495047:asmarine I; C495049:asmarine J; C495048:asmarine K