title: Unmasking hypotension by beta lactam during dextran sulfate low-density lipoprotein apheresis.
abstract: The authors report, for the first time, potentially fatal adverse effects of combined treatment using beta lactam and low-density lipoprotein (LDL) apheresis with dextran sulfate adsorption. A 62-year-old man was receiving LDL apheresis because of peripheral artery disease. Cefmetazole was administered to treat infection of a leg ulcer. Although antibiotics alone did not cause any allergic reactions, he manifested circulatory collapse during LDL apheresis. Possible mechanisms for shock were discussed.
authors.affiliation: Shinjuku Suimei Clinic, Shinjuku, Tokyo, Japan.
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Takenaka
authors.forename: Masako
authors.initials: M
authors.lastname: Sakamoto
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Suzuki
mesh_terms: D001781:Blood Component Removal / Q000009:adverse effects / Q000379:methods*; D016264:Dextran Sulfate / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007022:Hypotension / Q000209:etiology*; D008077:Lipoproteins, LDL / Q000097:blood*; D008297:Male; D008875:Middle Aged; D047090:beta-Lactams / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D008077:Lipoproteins, LDL; D047090:beta-Lactams; D016264:Dextran Sulfate