[Association of polymorphic marker A1/A2 of gene ITGB3 with coronary artery disease and myocardial infarction].
The distributions of the alleles and genotypes of polymorphic marker A1/A2 of gene ITGB3 encoding the beta3 subunit of integrin alphaIIbbeta3 in groups of patients with coronary artery disease (CAD), including those who have had myocardial infarction (MI), and in the control group have been compared. Analysis using Fisher's test has not revealed significant differences between these groups with respect to the distributions of the alleles and genotypes of polymorphic marker A1/A2 of gene ITGB3. This indicates that this polymorphic marker is not associated with either CAD or MI in the Moscow population.
Chudakova
D A
DA
Minushkina
L O
LO
Zateĭshchikov
D A
DA
Nosikov
V V
VV
D016022:Case-Control Studies; D003327:Coronary Disease / Q000235:genetics*; D005260:Female; D005819:Genetic Markers / Q000235:genetics; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D006801:Humans; D039661:Integrin beta3 / Q000235:genetics*; D008297:Male; D009031:Moscow; D009203:Myocardial Infarction / Q000235:genetics*
D005819:Genetic Markers; C061248:ITGB3 protein, human; D039661:Integrin beta3