title: Antimicrobial therapy of community-acquired pneumonia.
abstract: Community-acquired pneumonia (CAP) is a common disorder that is potentially life-threatening, especially in older adults and patients with comorbid disease. Despite substantial progress in therapeutic options, CAP remains a primary cause of death from infectious disease in the United States. The mainstay of treatment for most patients is appropriate antimicrobial therapy This article reviews the principles for initial antimicrobial therapy, highlights some of the differences in approaches to antimicrobial drug selection in selected guidelines, and includes new recommendations for empiric and pathogen-directed therapy of CAP.
authors.affiliation: Summa Health System, 75 Arch Street, Suite 105, Akron, OH 44304, USA. filet@summa-health.org
authors.forename: Thomas M
authors.initials: TM
authors.lastname: File
authors.forename: Michael S
authors.initials: MS
authors.lastname: Niederman
mesh_terms: D000553:Ambulatory Care; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects; D017714:Community-Acquired Infections / Q000188:drug therapy; D004334:Drug Administration Schedule; D024901:Drug Resistance, Multiple, Bacterial; D004363:Drug Utilization; D006760:Hospitalization; D006801:Humans; D018410:Pneumonia, Bacterial / Q000188:drug therapy* / Q000382:microbiology; D017410:Practice Guidelines as Topic
chemical_list: D000900:Anti-Bacterial Agents