[A case of pulmonary nocardiosis with a polypoid lesion in a bronchus].
A 62-year-old woman was admitted with fever and bloody sputum. A mass shadow in the left S3 and obstruction of the left B3 were seen on a chest radiograph and CT. Obstructive pneumonia was suspected, and cefotiam and imipenem/cilastatin were administered. However, this treatment did not show adequate efficacy. Bronchoscopy demonstrated a yellowish-white polypoid lesion in the left B3, but histopathological findings with HE staining yielded no definite diagnosis. Subsequently, Nocardia asteroides was detected in sputum test. A sulfamethoxazole-trimethoprim combination and minocycline were administered, and the clinical findings improved. Gram-positive microfilaments were confirmed retrospectively in the pathologic specimen, and a diagnosis of pulmonary nocardiosis was made.
Morita
Hiroki
H
Department of Internal Medicine and Bioregulation, Nagoya City University Graduate School of Medical Sciences.
Torii
Masayoshi
M
Yokoyama
Takako
T
Ebi
Masahide
M
Takakuwa
Osamu
O
Nakamura
Atsushi
A
Usami
Ikuji
I
D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001982:Bronchial Diseases / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D008911:Minocycline / Q000008:administration & dosage; D009617:Nocardia Infections / Q000188:drug therapy* / Q000473:pathology; D009616:Nocardia asteroides / Q000302:isolation & purification; D011127:Polyps / Q000150:complications / Q000473:pathology*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000008:administration & dosage
D000900:Anti-Bacterial Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D008911:Minocycline