Tight blood glucose control: a recommendation applicable to any critically ill patient?
The issue of tight glucose control with intensive insulin therapy in critically ill patients remains controversial. Although compelling evidence supports this strategy in postoperative patients who have undergone cardiac surgery, the use of tight glucose control has been challenged in other situations, including in medical critically ill patients and in those who have undergone non-cardiac surgery. Similarly, the mechanisms that underlie the effects of high-dose insulin are not fully elucidated. These arguments emphasize the need to study the effects of tight glucose control in a large heterogeneous cohort of intensive care unit patients.
Devos
Philippe
P
Department of Intensive Care, Centre Hospitalier Universitaire du Sart Tilman, Liege, Belgium.
Preiser
Jean-Charles
JC
D001786:Blood Glucose / Q000187:drug effects; D016638:Critical Illness; D004198:Disease Susceptibility; D006801:Humans; D006943:Hyperglycemia / Q000188:drug therapy / Q000503:physiopathology; D007328:Insulin / Q000008:administration & dosage*; D007362:Intensive Care Units; D011182:Postoperative Care; D013903:Thoracic Surgery
D001786:Blood Glucose; D007328:Insulin