title: Carcinoma ex-pleomorphic adenoma of the breast. Report of three cases suggesting a relationship to metaplastic carcinoma of matrix-producing type.
abstract: Three cases of carcinoma ex-pleomorphic adenoma of the breast are reported. Patients were 82, 60 and 56 years old and presented with a breast lump. All tumours showed areas of pleomorphic adenoma adjacent to typical areas of malignant transformation. These cases add to the spectrum of tumours shared by breast and salivary gland. The relationship between these neoplasms and metaplastic carcinoma of matrix-producing type is discussed.
authors.affiliation: Department of Pathology, British Columbia Cancer Agency, Vancouver, BC, V5Z 4E6, Canada. mhayes@bccancer.bc.ca
authors.forename: Malcolm M
authors.initials: MM
authors.lastname: Hayes
authors.forename: David
authors.initials: D
authors.lastname: Lesack
authors.forename: Christophe
authors.initials: C
authors.lastname: Girardet
authors.forename: Marina
authors.initials: M
authors.lastname: Del Vecchio
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Eusebi
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology* / Q000628:therapy; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001365:Axilla; D044963:Biopsy, Fine-Needle; D001943:Breast Neoplasms / Q000473:pathology* / Q000628:therapy; D002471:Cell Transformation, Neoplastic; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008197:Lymph Node Excision; D015411:Mastectomy, Modified Radical; D015412:Mastectomy, Segmental; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant
chemical_list: D000970:Antineoplastic Agents