title: Synthetic approaches to the 2003 new drugs.
abstract: New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as drug-like leads for designing new future drugs. To these ends, this review covers the syntheses of 23 NCEs marketed in 2003.
authors.affiliation: Pfizer Global Research and Development, Pfizer Inc, Groton, CT 06340, USA. kevin_k_liu@groton.pfizer.com
authors.forename: Kevin K-C
authors.initials: KK
authors.lastname: Liu
authors.forename: Jin
authors.initials: J
authors.lastname: Li
authors.forename: Subas
authors.initials: S
authors.lastname: Sakya
mesh_terms: D015507:Drugs, Investigational / Q000138:chemical synthesis; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis*; D013678:Technology, Pharmaceutical / Q000379:methods* / Q000639:trends
chemical_list: D015507:Drugs, Investigational; D004364:Pharmaceutical Preparations