title: [Onychomatricoma, a rare lesion of the nail].
abstract: Onychomatricoma is a rare fibroepithelial lesion of the nail matrix with peculiar clinical and histological features. Clinically, it is characterized by a longitudinal band of yellow thickening of the nail plate with transverse overcurvature and splinter hemorrhages. Nail avulsion exposes a villous tumor of the matrix with filamentous digitations extending into multiple holes of the nail plate. Histologically, a thick keratogenous zone forms a thickened nail plate. The lesion in its proximal portion is characterized by deep epithelial invaginations and by a stroma organized in two layers. The distal zone corresponds to multiple fibroepithelial projections extending into the nail plate. The diagnosis can be difficult in the presence of misleading clinical features or when the specimen is incomplete or examined with an improper orientation. Surgical resection is the recommended treatment.
authors.affiliation: Service d'Anatomie Pathologique, France. ana.path@chu-limoges.fr
authors.forename: Isabelle
authors.initials: I
authors.lastname: Pommepuy
authors.forename: Denis
authors.initials: D
authors.lastname: Roblet
authors.forename: Sophie
authors.initials: S
authors.lastname: Blaise
authors.forename: Manuela
authors.initials: M
authors.lastname: Delage-Corre
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Bonnetblanc
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Fayol
authors.forename: François
authors.initials: F
authors.lastname: Labrousse
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D009260:Nail Diseases / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*