title: ACR classification criteria for systemic lupus erythematosus: complement components.
abstract: Complement is involved in the pathogenesis of systemic lupus erythematosus (SLE) and has also a seemingly paradoxical protective role in the development of the disease. Low levels of components within the classical pathway of complement especially C1q, C4 and C3 have a high specificity for SLE diagnosis and should be considered as promising for inclusion in classification criteria of SLE.
authors.affiliation: Department of Rheumatology, University Hospital, Sweden.
authors.forename: O
authors.initials: O
authors.lastname: Nived
authors.forename: G
authors.initials: G
authors.lastname: Sturfelt
mesh_terms: D015415:Biomarkers / Q000032:analysis; D015922:Complement C1q / Q000032:analysis; D003165:Complement System Proteins / Q000032:analysis*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000145:classification / Q000175:diagnosis*
chemical_list: D015415:Biomarkers; D015922:Complement C1q; D003165:Complement System Proteins