The effects of static magnetic field on action potential propagation and excitation recovery in nerve.
Calculations using the Hodgkin-Huxley and one-dimensional cable equations have been performed to determine the expected sensitivity of conduction and refractoriness to changes in the time constant of sodium channel deactivation at negative potentials, as reported experimentally by Rosen (Bioelectromagnetics 24 (2003) 517) when voltage-gated sodium channels are exposed to a 125 mT static magnetic field. The predicted changes in speed of conduction and refractory period are very small.
Hinch
R
R
Mathematical Institute, 24-29 St. Giles, Oxford, OX1 3LB, UK.
Lindsay
K A
KA
Noble
D
D
Rosenberg
J R
JR
D000200:Action Potentials / Q000502:physiology / Q000528:radiation effects*; D000818:Animals; D004594:Electrophysiology; D006801:Humans; D008280:Magnetics / Q000009:adverse effects*; D008959:Models, Neurological; D009431:Neural Conduction / Q000502:physiology / Q000528:radiation effects*; D009474:Neurons / Q000502:physiology / Q000528:radiation effects*