[Choosing of disaggregants for the treatment of patients with instable angina without lifting the ST segment].
The cases study dealt with choosing an individual antiaggregant therapy for patients with instable angina (IA) without lifting the ST segment. Seventy-eight patients with IA, who were treated, apart from routine therapy, by different disaggregants, were examined. The aggregation of platelets was tested on the laser LA 230 "Biola" analyzer, Russia. Aspirin effectively suppressed the adrenalin-induced aggregation of platelets in 20 of 26 patients; cardiomagnil effectively suppressed it in all 17 patients; and plavix reliably reduced the ADP-induced aggregation of platelets. Both types of platelets aggregation were reliably reduced in combined therapy (plavix plus cardiomagnil). Thus, the combined therapy by drugs with different action mechanisms was proven to most effective in patients with IA.
Poponina
T M
TM
Kapilevich
N A
NA
D000787:Angina Pectoris / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage*
D010975:Platelet Aggregation Inhibitors