[Action of vitamin D on mineralization].
The effects of 1,25 (OH) (2)D on bone mineralization appear to be indirect by stimulating the calcium and phosphate supply, mainly by absorption from intestine. The disturbance in vitamin D action results in rickets in infancy and osteomalacia in adults. An association has been recently reported between mild vitamin D insufficiency and decreased bone mineral density in the elderly, which enhances the importance of appropriate vitamin D intake.
Michigami
Toshimi
T
Department of Environmental Medicine, Osaka Medical Center and Research Institute for Maternal and Child Health.
D000818:Animals; D015519:Bone Density; D002113:Calcification, Physiologic; D002118:Calcium / Q000378:metabolism; D000089703:Fibroblast Growth Factor-23; D005346:Fibroblast Growth Factors / Q000502:physiology; D006801:Humans; D007408:Intestinal Absorption; D007687:Kidney Tubules, Proximal / Q000378:metabolism; D009999:Ossification, Heterotopic / Q000209:etiology; D010018:Osteomalacia / Q000209:etiology; D010281:Parathyroid Hormone / Q000502:physiology; D010758:Phosphorus / Q000378:metabolism; D018167:Receptors, Calcitriol / Q000502:physiology; D012279:Rickets / Q000209:etiology; D014807:Vitamin D / Q000008:administration & dosage / Q000009:adverse effects / Q000502:physiology*; D014808:Vitamin D Deficiency
D010281:Parathyroid Hormone; D018167:Receptors, Calcitriol; D014807:Vitamin D; D010758:Phosphorus; D005346:Fibroblast Growth Factors; D000089703:Fibroblast Growth Factor-23; D002118:Calcium