title: Mitochondrial function dependent proliferation assay for the diagnosis of mitochondrial disorders in human fibroblasts.
abstract: A media has been developed which enables the assessment of mitochondrial function in fibroblasts by measuring proliferation as an end point.
authors.affiliation: Biochemical Genetics Laboratory, Alberta Children's Hospital, Calgary, Alberta, Canada.
authors.forename: Stephen D
authors.initials: SD
authors.lastname: Hodges
authors.forename: Floyd F
authors.initials: FF
authors.lastname: Snyder
mesh_terms: D001706:Biopsy; D003585:Cell Biology; D049109:Cell Proliferation; D002478:Cells, Cultured; D003470:Culture Media / Q000494:pharmacology; D005347:Fibroblasts / Q000378:metabolism*; D005973:Glutamine / Q000378:metabolism; D006801:Humans; D007288:Inosine / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism*; D028361:Mitochondrial Diseases / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism; D010429:Pentoses / Q000378:metabolism
chemical_list: D003470:Culture Media; D010429:Pentoses; D005973:Glutamine; D007288:Inosine; D010100:Oxygen