[Studies on extraction process of Phyllanthus urinaria].
OBJECTIVE
To optimize the extraction process of Phyllanthus urinaria L.


METHODS
The optimum extraction condition was investigated by the orthogonal design in flavonoids content as index.


RESULTS
The factors influencing extraction efficiency were as follows: D > A > B> C (A: Concentration of ethanol, B: The amount of ethanol added, C: Time of extraction, D: Times of extraction). The optimum extraction condition was: extracting the drug for 3 times, every time for 2 hour, after adding 8 fold of ethanol, utilizing concentration of ethanol for 70%.


CONCLUSIONS
The optimized process is stable and high efficient.
Li
W
W
College of Pharmacy, Xi'an Jiaotong University, Xi'an 710061.
Niu
X
X
D002626:Chemistry, Pharmaceutical / Q000379:methods; D004339:Drug Compounding; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification*; D000431:Ethanol; D005419:Flavonoids / Q000032:analysis / Q000302:isolation & purification; D029803:Phyllanthus / Q000737:chemistry*; D013647:Task Performance and Analysis
D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D000431:Ethanol