'Cerebral palsy' due to mitochondrial cytopathy.
Two children aged 10 and 13 years with initially static motor problems, diagnosed as cerebral palsy, were found to have respiratory chain defects after developing a progressive course and multisystem involvement. Mitochondrial cytopathies should be considered in the differential diagnosis of cerebral palsy.
Mordekar
S R
SR
Department of Paediatric Neurology, Sheffield Children's Hospital, Western Bank, Sheffield, United Kingdom. smordekar@yahoo.com
Baxter
P S
PS
D000293:Adolescent; D001921:Brain / Q000473:pathology*; D002547:Cerebral Palsy / Q000175:diagnosis* / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D009877:Endophthalmitis / Q000209:etiology; D005260:Female; D013006:Growth Hormone / Q000172:deficiency; D006801:Humans; D007223:Infant; D007625:Kearns-Sayre Syndrome / Q000150:complications / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D009123:Muscle Hypotonia / Q000209:etiology; D009132:Muscles / Q000473:pathology
D013006:Growth Hormone