Fertility after ovarian drilling by transvaginal fertiloscopy for treatment of polycystic ovary syndrome.
OBJECTIVE
To evaluate fertiloscopy ovarian drilling with bipolar energy in women with clomiphene citrate-resistant polycystic ovary syndrome (PCOS).


METHODS
Prospective study (Canadian Task Force classification II).


METHODS
University teaching hospital and private clinic.


METHODS
Eighty women with clomiphene citrate-resistant PCOS.


METHODS
Operative transvaginal fertiloscopy with a coaxial bipolar electrode.


RESULTS
During a mean follow-up of 18.1 months (+/- 6.4), 73 women (91%) recovered regular and ovulatory cycles. The cumulative pregnancy rate was 60% (44/73) for spontaneous and stimulated cycles, with 39.7% (29/73) imputed to drilling alone. The mean time to conceive was 3.9 months (range 1-11.8). There were eight miscarriages (18%), and no ectopic pregnancies or multiple pregnancy. No complications occurred.


CONCLUSIONS
Ovarian drilling by transvaginal fertiloscopy with bipolar electrosurgery appears to be an effective minimally invasive procedure in patients with PCOS resistant to clomiphene citrate.
Fernandez
Hervé
H
Service de Gynécologie-Obstétrique, Hôpital Antoine Béclère, Assistance Publique-Hôpitaux de Paris, Clamart, France.
Watrelot
Antoine
A
Alby
Jean-Dominique
JD
Kadoch
Jacques
J
Gervaise
Amélie
A
deTayrac
Renaud
R
Frydman
René
R
D000328:Adult; D002996:Clomiphene / Q000627:therapeutic use; D004598:Electrosurgery; D005260:Female; D005298:Fertility; D006801:Humans; D010053:Ovary / Q000601:surgery*; D011085:Polycystic Ovary Syndrome / Q000188:drug therapy / Q000601:surgery*; D011184:Postoperative Period; D011446:Prospective Studies; D017211:Treatment Failure
D002996:Clomiphene