Prevalence of hepatitis B and hepatitis C viral infections in Indian patients with chronic renal failure.
The present study reports prevalence of posttransplant hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in 256 patients with chronic renal failure (CRF) and with a history of either renal transplant or hemodialysis. Out of 256 patients 138 had renal transplant and 118 were on maintenance hemodialysis. Among the patients screened, 7% had HBV infection alone, 46% were infected with HCV alone, while 37.10% were found to have co-infection of both the viruses. Our findings implicate these viruses as the major cause of posttransplant hepatitis in Indian patients with CRF and indicate implementation of stringent screening procedures for these two viral infections.
Chandra
Madhavi
M
Center for Liver Research and Diagnostics, Deccan College of Medical Sciences and Allied Hospitals, Zafar Gadh, Kanchan Bagh, Hyderabad, India.
Khaja
Mohammad Nanne
MN
Hussain
Mohammad Mehaboob
MM
Poduri
Chetan Datta
CD
Farees
Nafeesa
N
Habeeb
Mohammad Aejaz
MA
Krishnan
Srinivasan
S
Ramareddy
Guntaka Venkata
GV
Habibullah
Chittoor Mohammad
CM
D004279:DNA, Viral / Q000032:analysis; D019694:Hepatitis B, Chronic / Q000150:complications / Q000453:epidemiology*; D019698:Hepatitis C, Chronic / Q000150:complications / Q000453:epidemiology*; D006801:Humans; D007194:India / Q000453:epidemiology; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D016030:Kidney Transplantation / Q000009:adverse effects; D015995:Prevalence; D006435:Renal Dialysis; D014184:Transplantation, Homologous
D004279:DNA, Viral