title: Rheolytic catheter thrombectomy, balloon angioplasty, and direct recombinant tissue plasminogen activator thrombolysis of dural sinus thrombosis with preexisting hemorrhagic infarctions.
abstract: We describe the case of a 28-year-old obtunded woman who presented with bilateral anterior parietal lobe cortical hemorrhages associated with thrombosis of the superior sagittal sinus, both transverse and sigmoid sinuses, and multiple cortical veins draining into the sagittal sinus. Initial heparin therapy was not effective. A combination of AngioJet rheolytic catheter thrombectomy, balloon angioplasty, and continuous direct superior sagittal sinus recombinant tissue plasminogen activator infusion led to venous recanalization with a successful clinical outcome, without worsening of the preexisting intracranial hemorrhages.
authors.affiliation: Department of Neuroradiology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
authors.forename: Kenneth R
authors.initials: KR
authors.lastname: Curtin
authors.forename: Ali
authors.initials: A
authors.lastname: Shaibani
authors.forename: Scott A
authors.initials: SA
authors.lastname: Resnick
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Russell
authors.forename: Tanya
authors.initials: T
authors.lastname: Simuni
mesh_terms: D000328:Adult; D000800:Angioplasty, Balloon; D002543:Cerebral Hemorrhage / Q000150:complications; D002544:Cerebral Infarction / Q000150:complications; D004388:Dura Mater; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D010690:Phlebography; D011994:Recombinant Proteins / Q000627:therapeutic use; D012851:Sinus Thrombosis, Intracranial / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D017131:Thrombectomy / Q000379:methods*; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents; D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator