Kidney transplantation from non heart-beating donors.
The use of non heart-beating donor (NHBD) kidneys to expand transplant programmes offers an answer to the problem of donor shortage. This source of kidneys is utilised by very few renal transplant units despite longstanding and growing evidence of equivalent graft function and survival, compared with cadaveric donor organs. This article reviews the selection criteria, technical approaches and logistical organisation involved in NHBD kidney retrieval and transplantation and outlines the evidence for graft function and survival, and patient outcome. The ethical and legal implications of running a NHBD programme are discussed, and some areas of current and likely future research are covered.
Brook
N R
NR
The University Division of Transplant Surgery, Leicester General Hospital, Gwendolen Road, Leicester, LE1 6GF. nicholasbrook@fastmail.fm
Nicholson
M L
ML
D006084:Graft Rejection; D006801:Humans; D007036:Hypothermia, Induced; D016030:Kidney Transplantation / Q000379:methods; D009926:Organ Preservation; D018579:Patient Selection; D010477:Perfusion; D014019:Tissue Donors