[Topical application of morphine gel in inflammatory mucosal and cutaneous lesions].
OBJECTIVE
The aim of this study was to demonstrate a peripheral local opioid effect using case examples involving inflammatory mucosal and cutaneous lesions.


METHODS
A 0.1% morphine gel, mixed in the hospital pharmacy, was applied several times daily to inflammatory mucosal lesions (oral, anogenital and in one patient to a skin ulcer). The effects and side effects were documented.


RESULTS
All patients experienced a significant reduction in pain with the use of topical morphine gel and no side effects were seen.


CONCLUSIONS
Topical peripheral application of morphine gel is a simple, effective method that can be carried out by patients several times a day with few side effects.
Platzer
M
M
Abteilung für Anästhesiologie und allgemeine Intensivmedizin, LKH Klagenfurt.
Likar
R
R
Stein
C
C
Beubler
E
E
Sittl
R
R
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage* / Q000627:therapeutic use*; D009092:Mucous Membrane / Q000187:drug effects / Q000473:pathology; D012871:Skin Diseases / Q000503:physiopathology*; D012883:Skin Ulcer / Q000503:physiopathology*
D000701:Analgesics, Opioid; D009020:Morphine