[Identification of RNA-recognizing modules on the surface of ribosomal proteins].
Properties of specific interaction between ribosomal proteins and ribosomal RNAs were analyzed and a method for determination of "recognizing modules" on the protein surface was proposed. The method is based on the search of protein atoms making conserved H-bonds with RNA and forming an invariant spatial structure in homologous rRNA-protein complexes and in the isolated protein. A potential of the method is demonstrated on the determination of the recognizing modules on the surfaces of ribosomal proteins S8, S15 and L5.
Nevskaia
N A
NA
Nikonov
O S
OS
Revtovich
S V
SV
Garber
M B
MB
Nikonov
S V
SV
D001419:Bacteria / Q000378:metabolism; D006860:Hydrogen Bonding; D015394:Molecular Structure; D009154:Mutation / Q000235:genetics; D012335:RNA, Ribosomal / Q000378:metabolism*; D012269:Ribosomal Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*
D012335:RNA, Ribosomal; D012269:Ribosomal Proteins