title: MR spectroscopy in the diagnosis of cerebral amyloid angiopathy presenting as a brain tumor.
abstract: We present two cases of focal, tumefactive, masslike lesions of diffuse cerebral amyloid angiopathy (CAA) that presented as areas of increased signal intensity on long TR sequences without contrast enhancement or restricted diffusion. MR spectroscopy revealed normal metabolite ratios and unremarkable spectra. Pathologic tissue showed CAA and CAA with angitis of the CNS. Tumefactive CAA is a rare condition, and we describe its characteristics at MR spectroscopy and diffusion-weighted imaging.
authors.affiliation: Department of Radiology, Neuroradiology Section, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.
authors.forename: Yair
authors.initials: Y
authors.lastname: Safriel
authors.forename: Gordon
authors.initials: G
authors.lastname: Sze
authors.forename: Kaye
authors.initials: K
authors.lastname: Westmark
authors.forename: Joachim
authors.initials: J
authors.lastname: Baehring
mesh_terms: D000368:Aged; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis*; D016657:Cerebral Amyloid Angiopathy / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000150:complications / Q000473:pathology; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D014657:Vasculitis / Q000150:complications / Q000473:pathology