title: Severe calcinosis cutis in an infant.
abstract: We report on an infant with severe asphyxia and persistent pulmonary hypertension as a newborn. The baby received prolonged intravenous calcium gluconate therapy for hypocalcemia. At 5 weeks of age, multiple firm, indurated areas (armor-like lesions) were palpable in the subcutaneous tissues of the trunk, arms, legs, and face, particularly in skin folds. Roentgenographic study showed generalized soft-tissue calcifications throughout the body, extremities, and face. Calcinosis cutis occurs through a variety of pathogenetic mechanisms. Case reports on calcinosis cutis in infants are uncommon, and the calcifications are mostly localized. In our patient, they are generalized.
authors.affiliation: Department of Pediatrics, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA. surasak1@aol.com
authors.forename: Surasak
authors.initials: S
authors.lastname: Puvabanditsin
authors.forename: Eugene
authors.initials: E
authors.lastname: Garrow
authors.forename: Ruetima
authors.initials: R
authors.lastname: Titapiwatanakun
authors.forename: Rahel
authors.initials: R
authors.lastname: Getachew
authors.forename: Jigneshkumar B
authors.initials: JB
authors.lastname: Patel
mesh_terms: D001238:Asphyxia Neonatorum / Q000150:complications; D002114:Calcinosis / Q000209:etiology*; D002125:Calcium Gluconate / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006996:Hypocalcemia / Q000188:drug therapy; D007231:Infant, Newborn; D010547:Persistent Fetal Circulation Syndrome / Q000150:complications; D012075:Remission, Spontaneous; D012871:Skin Diseases / Q000209:etiology*
chemical_list: D002125:Calcium Gluconate