Concordance correlation in the measurements of time to event.
The concordance correlation coefficient (CCC), a measure of concordance in ratings from multiple raters, was used to study inter-rater agreement in measurements of time to event, generally not observed with perfect consistency among raters. As a function of the first two moments of rating measures, the CCC can be estimated with data subject to censoring, using a likelihood-based estimation method applied under the assumptions of random censoring and parametric distribution models for the ratings of time to event. A simulation study was conducted for small sample performance under various censoring proportions. The use of the CCC with censored data is illustrated with an example taken from a data set containing data on time to an event with two raters per subject.
Liu
Xinhua
X
Department of Biostatistics, New York State Psychiatric Institute & Columbia University, New York, NY 10032, USA. x126@columbia.edu
Du
Yunling
Y
Teresi
Jeanne
J
Hasin
Deborah S
DS
D000293:Adolescent; D000328:Adult; D003198:Computer Simulation; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D008137:Longitudinal Studies; D008297:Male; D001523:Mental Disorders / Q000150:complications; D008875:Middle Aged; D015588:Observer Variation; D015203:Reproducibility of Results; D018709:Statistics, Nonparametric; D019966:Substance-Related Disorders / Q000150:complications