title: [Alkylphenols in the environment: a risk for human health?].
abstract: Endocrine Disrupting Chemicals (ECD) are a class of chemical compounds widely utilized for many industrial and civil applications and, consequently, widely diffused in the environment. Due to their chemical-physical characteristics, ECD may interfere with several endocrine functions in humans. Alkylphenols (APs), mainly produced by biodegradation of alkylphenols polyethoxylates surfactants, are a relevant group of ECD, both for their environmental diffusion and demonstrated estrogenic activity. Aim of this paper is to assess the potential risk of exposure to APs for humans, on the basis of the available data in literature concerning APs: environmental levels, accumulation in sediments and biota, toxicological effects on experimental animals.
authors.affiliation: Dipartimento di Scienze di Sanità Pubblica G. Sanarelli, Università degli Studi di Roma La Sapienza.
authors.forename: F
authors.initials: F
authors.lastname: Ensabella
authors.forename: F
authors.initials: F
authors.lastname: Materazzo
authors.forename: T
authors.initials: T
authors.lastname: Severi
authors.forename: M
authors.initials: M
authors.lastname: Vitali
mesh_terms: D000818:Animals; D004702:Endocrine Glands / Q000187:drug effects; D004700:Endocrine System Diseases / Q000139:chemically induced*; D004787:Environmental Pollution / Q000009:adverse effects* / Q000032:analysis; D006801:Humans; D010636:Phenols / Q000009:adverse effects* / Q000032:analysis; D012307:Risk Factors; D014877:Water Pollution, Chemical / Q000009:adverse effects / Q000032:analysis
chemical_list: D010636:Phenols