title: Localization and quantification of mitral valve prolapse using three-dimensional echocardiography.
abstract: OBJECTIVE
  Mitral valve prolapse is a common source of severe mitral regurgitation in Western countries. Three-dimensional echocardiography can provide views of the entire valve, allowing a complete assessment of the valve leaflets and commissures. It has the potential to precisely locate and quantify mitral valve prolapse.
  
  
  RESULTS
  Between January 1997 and December 2000, 91 patients with severe mitral regurgitation due to mitral valve prolapse underwent a transesophageal echocardiography with three-dimensional reconstruction of the mitral valve as part of their pre-operative work-up. The location and extent of the prolapse by echo was compared to the surgical status. The volume of prolapsing leaflet was calculated and compared to the volume of resected tissue whenever a repair was attempted. There was an excellent correspondence between the echographic localization of the prolapse and surgical inspection, and between the volume of prolapsing and surgically resected tissue (r=0.94, p<0.0001).
  
  
  CONCLUSIONS
  In patients with severe mitral regurgitation due to mitral valve prolapse, 3D echo allowed a precise localization and an accurate quantification of the prolapsing portion of the leaflets. This technique can provide refinements in the surgical planning of mitral valve repair and in the selection of candidates for this intervention.
authors.affiliation: Division of Cardiology, the Department of Cardiothoracic Surgery and the Department of Anesthesiology, University Hospital Lausanne, BH 16, 1011 Lausanne-CHUV, Switzerland. alain.delabays@chuv.hospvd.ch
authors.forename: A
authors.initials: A
authors.lastname: Delabays
authors.forename: X
authors.initials: X
authors.lastname: Jeanrenaud
authors.forename: P-G
authors.initials: PG
authors.lastname: Chassot
authors.forename: L K
authors.initials: LK
authors.lastname: Von Segesser
authors.forename: L
authors.initials: L
authors.lastname: Kappenberger
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019560:Echocardiography, Three-Dimensional / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008945:Mitral Valve Prolapse / Q000000981:diagnostic imaging*; D011446:Prospective Studies