title: Kaposiform hemangioendothelioma: the first reported case in a nonhuman animal species.
abstract: Kaposiform hemangioendothelioma is a rare vascular tumor that almost exclusively occurs in children. It is a low-grade malignant neoplasm that is locally aggressive but without proven metastatic potential. Herein, we describe a case of Kaposiform hemangioendothelioma in a 10-year-old male dog. To the best of our knowledge, this is the first report of this vascular tumor occurring in a nonhuman animal species. The tumor was located on the ventromedial surface of the posterior limb. Microscopic examination of the lesion revealed a multinodular tumor with sheets of spindled endothelial cells forming vascular slits similar to Kaposi's sarcoma and peripheral tumor lobules resembling capillary hemangioma.
authors.affiliation: Department of Pathology, University of Miami/Jackson Memorial Medical Center, 1611 North West 12 Avenue, Holtz Center, Room 2042, Miami, FL 33136, USA. vvincek@med.miami.edu
authors.forename: V
authors.initials: V
authors.lastname: Vincek
authors.forename: L
authors.initials: L
authors.lastname: Zaulyanov
authors.forename: M
authors.initials: M
authors.lastname: Mirzabeigi
mesh_terms: D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D006390:Hemangioendothelioma / Q000473:pathology / Q000662:veterinary*; D006394:Hemangiosarcoma / Q000473:pathology / Q000662:veterinary*; D008297:Male; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology / Q000662:veterinary*