title: Malignant rhabdoid tumor of the kidney in a child: report of a case with recurrence in the contralateral kidney.
abstract: BACKGROUND
  Malignant rhabdoid tumor (MRT) of the kidney is a rare and aggressive neoplasm with a controversial histogenesis. Although their immunohistochemistry may be diverse, the rhabdoid phenotype and mutations of the INI1 gene are consistently exhibited by MRTs regardless of their location.
  
  
  METHODS
  MRT recurred in the contralateral kidney in a 12-month-old child within 6 months after the initial histologic diagnosis, nephrectomy and autologous stem cell transplant. The presence of widespread metastases at the time of the recurrence precluded any further chemical and surgical diagnostic or therapeutic intervention.
  
  
  CONCLUSIONS
  To the best of our knowledge, only a few cases describing the cytologic diagnosis of MRT of the kidney in a child have been reported. This case illustrates the usefulness of cytologic diagnosis in an MRT recurrence.
authors.affiliation: Department of Pathology, Long Island Jewish Medical Center, New Hyde Park, New York 11040, USA.
authors.forename: Rubina S
authors.initials: RS
authors.lastname: Cocker
authors.forename: Mona
authors.initials: M
authors.lastname: Sharaan
authors.forename: Patricia
authors.initials: P
authors.lastname: Wasserman
mesh_terms: D014408:Biomarkers, Tumor; D044963:Biopsy, Fine-Needle; D002467:Cell Nucleus / Q000473:pathology; D003593:Cytoplasm / Q000473:pathology; D018450:Disease Progression; D017809:Fatal Outcome; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D007633:Keratins / Q000378:metabolism; D007668:Kidney / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D008297:Male; D009362:Neoplasm Metastasis / Q000000981:diagnostic imaging / Q000473:pathology; D009392:Nephrectomy; D011859:Radiography; D012008:Recurrence; D018335:Rhabdoid Tumor / Q000000981:diagnostic imaging / Q000473:pathology* / Q000556:secondary; D033581:Stem Cell Transplantation; D014182:Transplantation, Autologous; D014746:Vimentin / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; D014746:Vimentin; D007633:Keratins