Meningiomas invading the superior sagittal sinus: surgical experience in 108 cases.
OBJECTIVE
Radical resection of meningiomas invading the superior sagittal sinus (SSS) presents several hazards. Some surgeons consider SSS invasion a contraindication for complete resection, and others advocate total resection with venous reconstruction. There is a lack of published large series to provide definitive guidelines for the surgical treatment of these complex cases. We report our 15-year experience with surgery of parasagittal meningiomas invading the SSS.


METHODS
Between 1986 and 2001, 108 patients (73 women, 35 men; age range, 22-83 yr; mean age, 56.2 yr) underwent surgery at the Neurological Institute "C. Besta" of Milan for tumors invading the SSS. Parasagittal meningiomas not invading the SSS were excluded from this series.


RESULTS
Simpson Grade I to II removal was achieved in 100 patients. Thirty patients with meningiomas totally occluding the SSS had complete resection of the encased portion of the sinus. Histological examination revealed 86 benign (79.6%), 16 atypical (14.8%), and 4 malignant (3.7%) meningiomas along with 2 hemangiopericytomas. There were two perioperative deaths. Serious complications included brain swelling (nine patients; 8.3%) and postoperative hematoma (two patients; 1.85%). Follow-up ranged from 19 to 223 months (mean, 79.5 mo). One patient was lost to follow-up. Tumors recurred in 15 patients (13.9%). After multivariate analysis, histological type, tumor size, and Simpson grade were confirmed as significant independent prognostic factors for recurrence.


CONCLUSIONS
On the basis of our results, we conclude that if the sinus is partially invaded, it can be opened to obtain as complete a resection as possible and to attempt to preserve the patency of the sinus. If the sinus is obstructed, the portion of the sinus involved can be resected completely. In both situations, extreme care is vital to preservation of cortical veins, which may offer important collateral drainage. With our approach, good results are achieved and it is not necessary to reconstruct the sinus.
DiMeco
Francesco
F
Department of Neurosurgery, Istituto Nazionale Neurologico C. Besta, 20133 Milan, Italy. fdimeco@jhmi.edu
Li
Khan W
KW
Casali
Cecilia
C
Ciceri
Elisa
E
Giombini
Sergio
S
Filippini
Graziella
G
Broggi
Giovanni
G
Solero
Carlo L
CL
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003392:Cranial Sinuses / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008016:Life Change Events; D008297:Male; D008577:Meningeal Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D008579:Meningioma / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D008875:Middle Aged; D009017:Morbidity; D009361:Neoplasm Invasiveness / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D015996:Survival Rate; D016896:Treatment Outcome