title: [Retroperitoneal lymph node metastasis in epithelial cancer of the ovary: a report of 58 cases].
abstract: OBJECTIVE
  To analyze the retroperitoneal lymph node metastasis in epithelial cancer of the ovary and offer scientific indications for lymph node radical dissection.
  
  
  METHODS
  Fifty-eight patients with ovarian cancer treated from January 1990 to December 2000 were retrospectively reviewed. Single-factor and multifactor analysis with Logistic regression model were performed by SPSS 10.0 statistic software.
  
  
  RESULTS
  The metastasis rates of overall lymph nodes, pelvic nodes and para-aortic nodes were 48.3%, 37.9% and 25.9% respectively, among which no significant difference was noted (P > 0.05). Single-factor analysis showed that tumor location, ascitic condition, clinical stage and the size of residual tumor were associated with retroperitoneal lymph node metastasis. Multifactor analysis revealed that clinical stage and size of residual tumor were independent risk factors for metastasis of retroperitoneal lymph nodes.
  
  
  CONCLUSIONS
  For early ovarian cancer patients, it is extremely important to perform radical dissection of the retroperitoneal lymph nodes. For advanced or residual lesions, radical dissection of pelvic nodes and para-aortic nodes could be considered in the second exploration.
authors.affiliation: Department of Gynecology, Fujian Tumor Hospital, Fuzhou 350014, China. fzxr@21cn.com
authors.forename: Rong
authors.initials: R
authors.lastname: Xie
authors.forename: Yu-Zhen
authors.initials: YZ
authors.lastname: Lin
authors.forename: Gui-Lin
authors.initials: GL
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage; D018282:Cystadenocarcinoma, Mucinous / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D018284:Cystadenocarcinoma, Serous / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D004317:Doxorubicin / Q000008:administration & dosage / Q000031:analogs & derivatives; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D012187:Retroperitoneal Space; D012189:Retrospective Studies; D024162:Second-Look Surgery
chemical_list: D004317:Doxorubicin; D003520:Cyclophosphamide; D002945:Cisplatin