[Fluorescent probes for intracellular Mg2+ measurement].
Recently, fluorescent probes are widely used as tools for dynamical measurement of ion distributions and concentrations in cells. They are highly sensitive, and offer imaging by the use of fluorescent microscopy in easily and less cell damaging way. This paper discusses the selectivity and optical character of the three novel Mg(2+) fluorescent probes. KMG-20AM offers ratiometric quantative measurement of Mg(2+), KMG-104 provides high-sensitive qualitative analysis and 3-D measurement. With those improved Mg(2+) fluorescent probes, the physiological and pathological role of Mg(2+) are going to be more and more clear.
Komatsu
Hirokazu
H
Department of Applied Chemistry, Faculty of Science and Technology, Keio University.
Suzuki
Yoshio
Y
Suzuki
Koji
K
D002413:Cations, Divalent; D005456:Fluorescent Dyes; D006801:Humans; D008274:Magnesium / Q000032:analysis*; D008856:Microscopy, Fluorescence; D012680:Sensitivity and Specificity
D002413:Cations, Divalent; D005456:Fluorescent Dyes; D008274:Magnesium