title: Carbapenem-resistant Pseudomonas aeruginosa outbreak in an intensive care unit of a teaching hospital.
abstract: The genetic similarity of carbapenem-resistant Pseudomonas aeruginosa strains isolated in the Hospital Universitário São Francisco, Bragança Paulista, São Paulo, Brasil, was evaluated by pulsed field gel electrophoresis (PFGE). A unique clone was detected among 5 of 7 isolates, suggesting that cross-contamination might have played a role in the spread of carbapenem-resistant P. aeruginosa strains. Interestingly, a similar PFGE pattern was encountered in a P. aeruginosa strain isolated from Hospital São Paulo that was used as a PFGE control.
authors.affiliation: Division of Infectious Diseases, São Francisco University, Bragança Paulista, SP, Brazil. galesac@aol.com
authors.forename: Ana C
authors.initials: AC
authors.lastname: Gales
authors.forename: Patrícia L
authors.initials: PL
authors.lastname: Torres
authors.forename: Dominique S O
authors.initials: DS
authors.lastname: Vilarinho
authors.forename: Renata S
authors.initials: RS
authors.lastname: Melo
authors.forename: Claudinéia F L
authors.initials: CF
authors.lastname: Silva
authors.forename: Rosângela F
authors.initials: RF
authors.lastname: Cereda
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001938:Brazil / Q000453:epidemiology; D015780:Carbapenems / Q000494:pharmacology*; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D004196:Disease Outbreaks; D024881:Drug Resistance, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D005838:Genotype; D006744:Hospital Bed Capacity, 100 to 299; D006784:Hospitals, Teaching; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011552:Pseudomonas Infections / Q000453:epidemiology / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D015780:Carbapenems