title: Usefulness of PCR analysis for diagnosis of alveolar echinococcosis with unusual localizations: two case studies.
abstract: The report presents two cases where diagnosis of alveolar echinococcosis was confirmed by Echinococcus multilocularis and Echinococcus granulosus PCR. The extrahepatic osseous involvement and the absence of initial hepatic involvement are unusual in both cases. Due to limitations of serological interpretation, PCR was useful to diagnose atypical echinococcosis.
authors.affiliation: Institut de Parasitologie et de Pathologie Tropicale, Faculté de Médecine, Hôpitaux Universitaires de Strasbourg, 3 rue Koeberlé, 67000 Strasbourg, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Georges
authors.forename: Odile
authors.initials: O
authors.lastname: Villard
authors.forename: Denis
authors.initials: D
authors.lastname: Filisetti
authors.forename: Alexander
authors.initials: A
authors.lastname: Mathis
authors.forename: Luc
authors.initials: L
authors.lastname: Marcellin
authors.forename: Yves
authors.initials: Y
authors.lastname: Hansmann
authors.forename: Ermanno
authors.initials: E
authors.lastname: Candolfi
mesh_terms: D000818:Animals; D018509:DNA, Helminth / Q000032:analysis; D004443:Echinococcosis / Q000175:diagnosis* / Q000469:parasitology; D048209:Echinococcus granulosus / Q000235:genetics / Q000302:isolation & purification*; D048210:Echinococcus multilocularis / Q000235:genetics / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction / Q000379:methods*; D013166:Spondylitis / Q000469:parasitology*; D013904:Thoracic Vertebrae / Q000469:parasitology*
chemical_list: D018509:DNA, Helminth