Cell migration: an overview.
Cell migration is an essential process for normal development and homeostasis that can also contribute to important pathologies. Not surprisingly, there is considerable interest in understanding migration on a molecular level, but this is a difficult task. However, technologies are rapidly emerging to address the major intellectual challenges associated with migration. In this chapter, we outline the basics of cell migration with an emphasis on the diverse systems, methodologies, and techniques described in this book. From the contributions presented, it is apparent that the next few years should produce major advances in our understanding of cell migration.
Webb
Donna J
DJ
Department of Cell Biology, University of Virginia, Charlottesville, VA, USA.
Zhang
Huaye
H
Horwitz
Alan F
AF
D000818:Animals; D002448:Cell Adhesion; D002465:Cell Movement / Q000502:physiology*; D016764:Cell Polarity