title: Successful use of the frontrunner catheter in the treatment of in-stent coronary chronic total occlusions.
abstract: Percutaneous intervention of coronary chronic total occlusion (CTO) from in-stent restenosis (ISR) is hindered by difficulty to cross the lesion with conventional guidewires. This study describes the successful treatment of five cases of CTOs from ISR using the Frontrunner controlled blunt microdissection catheter. Four of the five cases had failed previous attempts of percutaneous intervention with conventional guidewires. The Frontrunner catheter successfully facilitated the placement of guidewire into the distal true lumen in all five cases. The median crossing time was 10 min. No subintimal delivery of guidewire or vascular perforation was observed. TIMI 3 flow was achieved in all target vessels after further balloon angioplasty or stenting. The Frontrunner device is a safe and effective tool in the treatment of CTOs from ISR.
authors.affiliation: Columbia University Medical Center and Cardiovascular Research Foundation, 161 Fort Washington Avenue, New York, NY 10032, USA.
authors.forename: Yi-Ming
authors.initials: YM
authors.lastname: Yang
authors.forename: Roxana
authors.initials: R
authors.lastname: Mehran
authors.forename: George
authors.initials: G
authors.lastname: Dangas
authors.forename: Arlene
authors.initials: A
authors.lastname: Reyes
authors.forename: Jenny
authors.initials: J
authors.lastname: Qin
authors.forename: Gregg W
authors.initials: GW
authors.lastname: Stone
authors.forename: Martin B
authors.initials: MB
authors.lastname: Leon
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Moses
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D019917:Blood Vessel Prosthesis Implantation; D006328:Cardiac Catheterization / Q000295:instrumentation*; D002908:Chronic Disease; D017023:Coronary Angiography; D003326:Coronary Circulation; D003327:Coronary Disease / Q000503:physiopathology / Q000628:therapy; D023903:Coronary Restenosis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015607:Stents