The ArrayExpress gene expression database: a software engineering and implementation perspective.
BACKGROUND
The lack of microarray data management systems and databases is still one of the major problems faced by many life sciences laboratories. While developing the public repository for microarray data ArrayExpress we had to find novel solutions to many non-trivial software engineering problems. Our experience will be both relevant and useful for most bioinformaticians involved in developing information systems for a wide range of high-throughput technologies.


RESULTS
ArrayExpress has been online since February 2002, growing exponentially to well over 10,000 hybridizations (as of September 2004). It has been demonstrated that our chosen design and implementation works for databases aimed at storage, access and sharing of high-throughput data.


BACKGROUND
The ArrayExpress database is available at http://www.ebi.ac.uk/arrayexpress/. The software is open source.


BACKGROUND
ugis@ebi.ac.uk.
Sarkans
Ugis
U
EMBL Outstation-Hinxton, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK. ugis@ebi.ac.uk
Parkinson
Helen
H
Lara
Gonzalo Garcia
GG
Oezcimen
Ahmet
A
Sharma
Anjan
A
Abeygunawardena
Niran
N
Contrino
Sergio
S
Holloway
Ele
E
Rocca-Serra
Philippe
P
Mukherjee
Gaurab
G
Shojatalab
Mohammadreza
M
Kapushesky
Misha
M
Sansone
Susanna-Assunta
SA
Farne
Anna
A
Rayner
Tim
T
Brazma
Alvis
A
D000465:Algorithms; D003628:Database Management Systems; D030541:Databases, Genetic; D020869:Gene Expression Profiling / Q000379:methods*; D033181:Information Dissemination / Q000379:methods; D016247:Information Storage and Retrieval / Q000379:methods*; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D011506:Proteins / Q000235:genetics* / Q000378:metabolism*; D012984:Software
D011506:Proteins