title: A second mitral valve replacement in a patient with hereditary hemorrhagic telangiectasia (Osler's disease).
abstract: A 62-year-old female with Osler's disease was admitted to our hospital because of fever and cardiac failure. The patient had undergone a mitral valve replacement (MVR) using a Carpentier-Edwards prosthetic valve 14 years earlier. A bacterial examination of arterial blood identified Streptococcus mitis. No arteriovenous malformations were detected in visceral organs. The patient underwent MVR using the same prosthetic xenograft after conservative treatment and management of repetitive epistaxis and decayed teeth. Intra- and postoperative bleeding were typical of a mitral valve reoperation. This is the first reported experience, to the best of our knowledge, of a second MVR in a patient with Osler's disease.
authors.affiliation: Second Department of Surgery, Gunma University Faculty of Medicine, Gunma 371-8511, Japan.
authors.forename: Susumu
authors.initials: S
authors.lastname: Ishikawa
authors.forename: Kiyohiro
authors.initials: K
authors.lastname: Oshima
authors.forename: Masahiro
authors.initials: M
authors.lastname: Aizaki
authors.forename: Toru
authors.initials: T
authors.lastname: Takahashi
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Hasegawa
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Morishita
mesh_terms: D004697:Endocarditis, Bacterial / Q000209:etiology / Q000601:surgery*; D005260:Female; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000601:surgery*; D012086:Reoperation; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications*