The influence of calorie restriction during the Ramadan fast on serum fructosamine and the formation of beta hydroxybutirate in type 2 diabetes mellitus patients.
OBJECTIVE
To determine whether the Ramadan fasting can improve metabolic control evaluated from serum fructosamine and beta hydroxybutirate in patients with Type 2 diabetes mellitus.


METHODS
This was a prospective one group before and after study (self-controlled study). Twenty four patients from the outpatient clinic of the Metabolic Endocrinology Division of the Department of Internal Medicine, Faculty of Medicine, University of Indonesia/ Cipto Mangunkusumo General Hospital who were well under control underwent assessment for serum fructosamine at weeks -1, 4, and 6 (2 weeks after the Ramadan fast) and beta hydroxybutirate formation at week 4.


RESULTS
The mean serum fructosamine on weeks -1, 4, and 6 were 334.2 +/-45.7; 303.9 +/-34.5 dan 313.6 +/-45.9 umol/L. The beta hydroxybutirate level was 0.3 mmol/L.


CONCLUSIONS
The Ramadan fasting in patients with well-controlled and medium-controlled type 2 diabetes mellitus could cause a reduction in serum fructosamine and does not cause formation of beta hyroxybutirate.
Gustaviani
Reno
R
Department of Internal Medicine, Faculty of Medicine, University of Indonesia-Dr. Cipto Mangunkusumo General Hospital, Jakarta.
Soewondo
Pradana
P
Semiardji
Gatut
G
Sudoyo
Aru W
AW
D020155:3-Hydroxybutyric Acid / Q000097:blood*; D000328:Adult; D000368:Aged; D000886:Anthropometry; D031204:Caloric Restriction; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D005215:Fasting; D005260:Female; D019270:Fructosamine / Q000097:blood*; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012068:Religion and Medicine
D008055:Lipids; D019270:Fructosamine; D020155:3-Hydroxybutyric Acid