[Influence of staphylococcal metabolites on adhesive reactions in the system "Candida albicans-buccal epitheliocytes"].
The influence of S. aureus and S. epidermitidis metabolites on the adhesive reactions in the system "C. albicans-buccal epitheliocytes" was studied. The study revealed that the treatment of C. albicans with S. aureus supernatants inhibited the adhesion of C. albicans to epitheliocytes, the degree of the inhibiting action of S. aureus supernatants in the system depending on their strain specificity. S. epidermitidis supernatants produced no adhesive effect. The irreversible decrease of the adhesive activity of C. albicans under the action of bacterial metabolites was, seemingly, the consequence of transformation of the receptor apparatus of C. albicans. At the same time S. aureus supernatants produced no essential influence on the adhesive potential and viability of buccal epitheliocytes.
Makhrova
T V
TV
Zaslavskaia
M I
MI
Maianskiĭ
A N
AN
D000293:Adolescent; D000328:Adult; D002176:Candida albicans / Q000187:drug effects / Q000502:physiology*; D002448:Cell Adhesion / Q000187:drug effects; D017077:Culture Media, Conditioned / Q000494:pharmacology; D004847:Epithelial Cells / Q000382:microbiology; D006801:Humans; D009061:Mouth Mucosa / Q000382:microbiology*; D013045:Species Specificity; D013211:Staphylococcus aureus / Q000254:growth & development / Q000378:metabolism*; D013212:Staphylococcus epidermidis / Q000254:growth & development / Q000378:metabolism*
D017077:Culture Media, Conditioned