title: The role of magnetic resonance imaging in diagnosis and management of breast cancer.
abstract: A review of the literature on the current applications of breast magnetic resonance imaging (MRI) indications, their rationale and their place in diagnosis and management of breast cancer was given. Contrast-enhanced breast MRI is developing as a valuable adjunct to mammography and sonography. Its high sensitivity for invasive breast cancer establishes its superiority in evaluation of multifocality/multicentricity, tumor response to neoadjuvant chemotherapy, detection of recurrence, and staging. Emerging applications include spectroscopy, usage of new contrast agents, and MRI-guided interventions, including noninvasive treatment of breast cancer. Its potential benefit in screening high-risk women has yet to be established with prospective studies, particularly with regard to false positive results.
authors.affiliation: Department of Radiology, University of North Carolina at Chapel Hill Medical School, CB 7510, 101 Manning Dr., Chapel Hill, NC 27599, USA. Dag_Pavic@med.unc.edu
authors.forename: Dag
authors.initials: D
authors.lastname: Pavic
authors.forename: Marcia A
authors.initials: MA
authors.lastname: Koomen
authors.forename: Cherie M
authors.initials: CM
authors.lastname: Kuzmiak
authors.forename: Y H
authors.initials: YH
authors.lastname: Lee
authors.forename: Etta D
authors.initials: ED
authors.lastname: Pisano
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008207:Lymphatic Metastasis / Q000175:diagnosis / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000295:instrumentation* / Q000379:methods*; D015412:Mastectomy, Segmental; D020360:Neoadjuvant Therapy