Structure elucidation by NMR spectroscopy of a new acetylated saponin from Centratherum anthelminticum.
A new glycosylated triterpene has been isolated from the seeds of Centratherum anthelminticum, a medicinally important plant. The structural analysis of its acetylated derivative was performed by 1H, 13C NMR, 1H-1H COSY, HMQC, HMBC and DEPT spectroscopy. The saponin was shown to contain hederagenin and six sugar residues forming two glycosyl chains. The complete structure of the saponin was established as 3-O-[beta-D-glucopyranosyl-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranosyl]-28-O-[beta-D-glucuronopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->3)-beta-D-glucopyranosyl]-hederagenin.
Mehta
B K
BK
School of Studies in Chemistry, Vikram University, Ujjain 456010 (M.P.), India. bkmehta@yahoo.com
Mehta
Darshana
D
Itoriya
Amrita
A
D019659:Asteraceae / Q000737:chemistry*; D002240:Carbohydrate Sequence; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification; D012639:Seeds / Q000737:chemistry
C500614:3-O-(glucopyranosyl-1-3-rhamnopyranosyl-1-2-arabinopyranosyl)-28-O-(glucopyranosyl-1-4-rhamnopyranosyl-1-3-glucopyranosyl)hedaragenin; D012503:Saponins; D009828:Oleanolic Acid; C025763:hederagenin