Synthesis of C-arylglycosides via Ru(II)-catalyzed [2 + 2 + 2] cycloaddition.
In the presence of catalytic amounts of Cp*RuCl(cod), the cycloaddition of 1,6-diynes with various C-alkynylglycosides proceeded at ambient temperature to afford C-arylglycosides in 46-93% yields.
Yamamoto
Yoshihiko
Y
Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Chikusa, Nagoya 464-8603, Japan. yamamoto@apchem.nagoya-u.ac.jp
Saigoku
Tomoaki
T
Ohgai
Takashige
T
Nishiyama
Hisao
H
Itoh
Kenji
K
D002384:Catalysis; D006027:Glycosides / Q000138:chemical synthesis*; D009005:Monosaccharides / Q000138:chemical synthesis*; D012428:Ruthenium / Q000737:chemistry
C438934:C-glycoside; D006027:Glycosides; D009005:Monosaccharides; D012428:Ruthenium