A new cytotoxic naphthoquinone from Paepalanthus latipes.
Quinones constitute an important class of naturally occurring compounds. They are found in plants, fungi and bacteria. Large number of quinones has been associated with antitumor, antibacterial, antimalarial and antifungal activities. In this work we describe the isolation, structure determination and the cytotoxic index of a new 1,4-naphthoquinone isolated from the capitula of Paepalanthus latipes.
Kitagawa
Rodrigo Rezende
RR
Instituto de Química de Araraquara, Universidade Estadual Paulista Júlio de Mesquita Filho, Rua Prof. Francisco Degni, Araraquara, SP, Brazil.
Raddi
Maria Stella Gonçalves
MS
Santos
Lourdes Campaner Dos
LC
Vilegas
Wagner
W
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D045744:Cell Line, Tumor; D039262:Eriocaulaceae / Q000737:chemistry*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D009285:Naphthoquinones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D017382:Reactive Oxygen Species; D021241:Spectrometry, Mass, Electrospray Ionization; D013778:Tetrazolium Salts; D013844:Thiazoles
D000972:Antineoplastic Agents, Phytogenic; D009285:Naphthoquinones; D017382:Reactive Oxygen Species; D013778:Tetrazolium Salts; D013844:Thiazoles; C022616:thiazolyl blue