Promethazine: a novel application as a neuroprotectant that reduces ischemia-mediated injury by inhibiting mitochondrial dysfunction.
Narayanan
Malini V
MV
Department of Neurosurgery, Brigham and Women's Hospital, Harvard University Medical School, Boston, Massachusetts, USA.
Zhang
Wenhua
W
Stavrovskaya
Irina G
IG
Kristal
Bruce S
BS
Friedlander
Robert M
RM
D000818:Animals; D015153:Blotting, Western; D002545:Brain Ischemia / Q000150:complications / Q000517:prevention & control*; D016923:Cell Death; D002540:Cerebral Cortex / Q000187:drug effects / Q000473:pathology; D006634:Histamine H1 Antagonists / Q000494:pharmacology* / Q000627:therapeutic use*; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D028361:Mitochondrial Diseases / Q000209:etiology / Q000517:prevention & control*; D018696:Neuroprotective Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D011398:Promethazine / Q000494:pharmacology* / Q000627:therapeutic use*
D006634:Histamine H1 Antagonists; D018696:Neuroprotective Agents; D011398:Promethazine