title: [Emotional processing in patients with a dissocial personality disorder subtype "psychopathy" according to PCL-R].
abstract: OBJECTIVE
  Functional MRI was used to test the effects of the deficient emotional responsiveness of psychopathic patients on cognitive processes.
  
  
  METHODS
  We used a Simon-paradigm, in which ten healthy volunteers and ten patients with a diagnosis of "psychopathy" (defined by Hare Psychopathy Checklist Revised) have to select their spatially defined responses on the basis of a nonspatial stimuli feature. For the emotion induction pictures from the International Affective Picture System (IAPS) were selected. At the beginning and intermediated by the Simon-paradigm blocks of positive, negative or neutral pictures were presented.
  
  
  RESULTS
  Patients with "psychopathy" exhibited untypical activation patterns in amygdala and prefrontal regions during interferences between negative or positive stimulations and cognitive tasks.
  
  
  CONCLUSIONS
  These results demonstrated disturbed regulation of emotion-cognition-interaction in "psychopathy" according to PCL-R.
authors.affiliation: Klinik für Forensische Psychiatrie der Universität Regensburg am Bezirksklinikum Regensburg. tatjana.weber@medbo.de
authors.forename: Tatjana
authors.initials: T
authors.lastname: Weber
authors.forename: Monika
authors.initials: M
authors.lastname: Sommer
authors.forename: Göran
authors.initials: G
authors.lastname: Hajak
authors.forename: Jürgen
authors.initials: J
authors.lastname: Müller
mesh_terms: D000328:Adult; D000339:Affect / Q000502:physiology*; D000679:Amygdala / Q000503:physiopathology; D000987:Antisocial Personality Disorder / Q000175:diagnosis / Q000503:physiopathology*; D001288:Attention / Q000502:physiology*; D001921:Brain / Q000503:physiopathology*; D004644:Emotions / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D009415:Nerve Net / Q000503:physiopathology; D009949:Orientation / Q000502:physiology; D010364:Pattern Recognition, Visual / Q000502:physiology; D011597:Psychomotor Performance / Q000502:physiology; D011930:Reaction Time / Q000502:physiology; D012016:Reference Values