title: Synthesis of a tripeptide derivative containing the gln-arg hydroxyethylene dipeptide isostere.
abstract: [structure: see text] The protected hydroxyethylene dipeptide isostere of Gln-Arg and the tripeptide derivative 1 were synthesized as components of potential peptidase inhibitors.
authors.affiliation: Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
authors.forename: Matthias
authors.initials: M
authors.lastname: Brewer
authors.forename: Clint A
authors.initials: CA
authors.lastname: James
authors.forename: Daniel H
authors.initials: DH
authors.lastname: Rich
mesh_terms: D001120:Arginine / Q000737:chemistry*; D004151:Dipeptides / Q000737:chemistry; D005030:Ethylenes / Q000737:chemistry*; D005973:Glutamine / Q000737:chemistry*; D007783:Lactones / Q000737:chemistry; D015394:Molecular Structure; D009842:Oligopeptides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D004151:Dipeptides; D005030:Ethylenes; D007783:Lactones; D009842:Oligopeptides; D005973:Glutamine; C067254:hydroxyethylene; D001120:Arginine