title: Ortho alkylation of aromatic ketimine with functionalized alkene by Rh(I) catalyst.
abstract: [reaction: see text] The reaction of the imine of aromatic ketones with functionalized alkenes was performed under a catalytic amount of (PPh3)3RhCl, and corresponding ortho-alkylated ketones were obtained after hydrolysis. A variety of functional groups in the alkene were tolerated in this ortho alkylation. This procedure expands the scope of ortho alkylation to the direct ortho functionalization of aromatic ketones.
authors.affiliation: Center for Bioactive Molecular Hybrid (CBMH), Department of Chemistry, Yonsei University, Seoul 120-749, Korea.
authors.forename: Sung-Gon
authors.initials: SG
authors.lastname: Lim
authors.forename: Jeong-Ae
authors.initials: JA
authors.lastname: Ahn
authors.forename: Chul-Ho
authors.initials: CH
authors.lastname: Jun