title: Consensus statement on antimicrobial treatment of odontogenic bacterial infections.
abstract: The infection of the oral cavity is a common public health problem and constant cause for antibiotic prescription, with 10% of antibiotics used to treat this problem. However, few studies have so far aimed to determine its incidence. Added to this, its relationship with certain sytemic diseases (cardiac, endocrine, etc) confers this pathology vital importance. In spite of the frequency and importance of odontogenic infection, the current dispersion in criteria regarding key aspects in classification, terminology and therapeutic recommendations is noticeable. The main objective of this document, compiled as a consensus statement by specialists in microbiology and odontology, is to establish useful recommendations for all of those involved in the clinical management of this pathology. Special attention has been placed on the rise in bacterial resistance observed over the last years, specifically the proliferation of betalactamase producing strains. Another important factor causing the resistance to appear is lack of therapeutic compliance, specially what regards dosage and treatment duration. Therefore, this pathology constitutes a complex problem which requires the instauration of broad spectrum antimicrobials, well tolerated and a convenient posology so that patients receive the adequate dose over the necessary period. High doses of amoxicillin/clavulanate (2000 mg/125 mg) have showed good results and power to overcome resistance. Other agents such as metronidazole and clindamycin, followed by de claritromycin and azithromycin have also proved to be active against most of microorganisms responsible for odontogenic infection.
authors.affiliation: Dpto de Estematología III, Facultad de Odontología de la Universidad Complutense de Madrid. Antbasco@arrakis.es
authors.forename: Antonio
authors.initials: A
authors.lastname: Bascones Martínez
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Aguirre Urízar
authors.forename: Ambrosio
authors.initials: A
authors.lastname: Bermejo Fenoll
authors.forename: Andrés
authors.initials: A
authors.lastname: Blanco Carrión
authors.forename: Cosme
authors.initials: C
authors.lastname: Gay-Escoda
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: González-Moles
authors.forename: José Luis
authors.initials: JL
authors.lastname: Gutiérrez Pérez
authors.forename: Yolanda
authors.initials: Y
authors.lastname: Jiménez Soriano
authors.forename: José
authors.initials: J
authors.lastname: Liébana Ureña
authors.forename: Joaquín Francisco
authors.initials: JF
authors.lastname: López Marcos
authors.forename: Juan Ramón
authors.initials: JR
authors.lastname: Maestre Vera
authors.forename: Evelio José
authors.initials: EJ
authors.lastname: Perea Pérez
authors.forename: José
authors.initials: J
authors.lastname: Prieto Prieto
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: de Vicente Rodríguez
mesh_terms: D001424:Bacterial Infections / Q000188:drug therapy*; D006801:Humans; D009059:Mouth Diseases / Q000188:drug therapy* / Q000382:microbiology*