Asymmetric synthesis of highly substituted beta-lactones by nucleophile-catalyzed [2+2] cycloadditions of disubstituted ketenes with aldehydes.
Wilson
Jonathan E
JE
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Fu
Gregory C
GC
D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D005030:Ethylenes / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
D000447:Aldehydes; D005030:Ethylenes; D007659:Ketones; D007783:Lactones; C008223:ketene