[Change of the cell immunity indexes in patients with multiple gastroduodenal ulcers under the influence of surgical treatment].
There were followed up 62 patients with multiple gastroduodenal ulcers. Before the operation in them distinct changes of the cell chain of immunity were established: T-lymphopenia, the T-lymphocytes subpopulations dysbalance, predominantly with reduction of the circulating T-helpers/inductors (CD4+) quantity with preservation on nearly normal and moderately subnormal level of T-suppressors/killers (CD8+), the immunoregulatory index (CD4/CD8) lowering. The quantity of B-lymphocytes (CD22+) was in normal limits or moderately reduced. Essential lowering of index of the lymphocytes blasttransformation reaction was noted, witnessing inhibition of the T-lymphocytes functional activity occurrence. Overall the data obtained have had witnessed the secondary immunodeficiency state presence, which deepened after operative intervention performance and was not removed as a result of the conventional treatment conduction.
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D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015703:Antigens, CD / Q000276:immunology; D004381:Duodenal Ulcer / Q000150:complications / Q000276:immunology / Q000601:surgery; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013276:Stomach Ulcer / Q000150:complications / Q000276:immunology / Q000601:surgery
D015703:Antigens, CD