Gabapentin for the treatment of itching produced by burns and wound healing in children: a pilot study.
We describe the use of gabapentin for the treatment of itching in wound healing in 35 children. All children were already treated with chlorpheniramine and trimeprazine but they remained irritable and were constantly rubbing their wounds. Within 24h of commencing treatment itching had improved significantly in all of the children.
Mendham
J E
JE
Department of Anaesthesia, Frenchay Hospital Frenchay, Bristol BS16 1LE, UK.
D000293:Adolescent; D000588:Amines / Q000009:adverse effects / Q000627:therapeutic use*; D000982:Antipruritics / Q000009:adverse effects / Q000627:therapeutic use*; D002056:Burns / Q000150:complications* / Q000503:physiopathology; D002648:Child; D002653:Child Behavior Disorders / Q000139:chemically induced; D002675:Child, Preschool; D003509:Cyclohexanecarboxylic Acids / Q000009:adverse effects / Q000627:therapeutic use*; D000077206:Gabapentin; D006801:Humans; D007223:Infant; D008297:Male; D011537:Pruritus / Q000188:drug therapy* / Q000209:etiology; D014945:Wound Healing / Q000502:physiology; D005680:gamma-Aminobutyric Acid / Q000009:adverse effects / Q000627:therapeutic use*
D000588:Amines; D000982:Antipruritics; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin