Cup inclination and serum concentration of cobalt and chromium after metal-on-metal total hip arthroplasty.
We investigated whether cup inclination influences serum levels of cobalt and chromium after metal-on-metal total hip arthroplasty. Out of a consecutive series, 3 groups of 20 patients each were established according to their cup inclination: greatest inclination (55 degrees -63 degrees, mean 58 degrees), intermediate inclination (44 degrees -46 degrees, mean 45 degrees), and smallest inclination (23 degrees -37 degrees, mean 33 degrees). We did not detect any statistically significant difference of serum cobalt (P = .23) or serum chromium (P = .13) levels between the 3 groups applying the Kruskal Wallis test. However, 3 patients with cup inclinations of 58 degrees , 63 degrees , and 61 degrees exhibited 9.8-53.6-fold elevated cobalt and 9.5-30.5-fold elevated chromium levels when compared with the median concentrations of this trial. We therefore recommend accurate cup placement also for metal-on-metal articulations.
Brodner
Wolfram
W
Department of Orthopaedics, Vienna General Hospital, Vienna, Austria.
Grübl
Alexander
A
Jankovsky
Rafael
R
Meisinger
Vanee
V
Lehr
Stephan
S
Gottsauner-Wolf
Florian
F
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip; D002857:Chromium / Q000097:blood*; D003035:Cobalt / Q000097:blood*; D006801:Humans; D008875:Middle Aged; D011474:Prosthesis Design
D002857:Chromium; D003035:Cobalt