Radiation-induced intracranial meningiomas: review of six operated cases.
It is well known that radiation can induce meningiomas. These tumors usually arise in patients with a history of low-dose radiation to the scalp for treatment of tinea capitis or high-dose radiation for a previous brain tumor. Radiation-associated meningiomas (RAMs) morphologically resemble their spontaneously arising counterparts. However, RAMs frequently present a more malignant phenotype and, as such, are diagnosed as "atypical" or "aggressive" meningiomas and occur predominantly in younger patients. This paper describes six cases of radiation-associated intracranial meningiomas in patients previously treated with low-dose radiation to the scalp for tinea capitis.
De Tommasi
Antonio
A
Department of Neurosurgery, University of Bari, Italy. adetommasi@neurosurgery.uniba.it
Occhiogrosso
Michele
M
De Tommasi
Claudio
C
Cimmino
Antonia
A
Sanguedolce
Francesca
F
Vailati
Giacomo
G
D016371:Cranial Irradiation / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000209:etiology* / Q000601:surgery; D008579:Meningioma / Q000175:diagnosis* / Q000209:etiology* / Q000601:surgery; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis* / Q000601:surgery; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D014006:Tinea Capitis / Q000532:radiotherapy