[Nitric oxide donors, a new treatment for insulin resistance, metabolic syndrome and diabetes?].
Obesity/insulin resistance ("diabesity") and the associated long term complications are reaching epidemic proportions worldwide. Recent evidence in experimental animals and humans shows that nitric oxide (NO) plays a key role in glucose and cardiovascular homeostasis. Pharmaceutical drugs releasing small and physiological amounts of NO may represent potential new treatments for insulin resistance.
Jayet
Pierre-Yves
PY
Département de médecine interne et Centre Botnar de Recherche Clinique, CHUV Lausanne.
Thalmann
Sébastien
S
Cook
Stéphane
S
Duplain
Hervé
H
Sartori
Claudio
C
Vollenweider
Peter
P
Scherrer
Urs
U
D003920:Diabetes Mellitus / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007333:Insulin Resistance; D024821:Metabolic Syndrome / Q000188:drug therapy* / Q000503:physiopathology; D009569:Nitric Oxide / Q000494:pharmacology; D020030:Nitric Oxide Donors / Q000494:pharmacology*; D009765:Obesity
D020030:Nitric Oxide Donors; D009569:Nitric Oxide