title: High-performance liquid chromatography of di- and trisubstituted aromatic positional isomers on 1,3-alternate 25,27-dipropoxy-26,28-bis-[3-propyloxy]-calix[4]arene-bonded silica gel stationary phase.
abstract: A new 1,3-alternate 25,27-dipropoxy-26,28-bis-[3-propyloxy]-calix[4]arene-bonded silica gel stationary phase (1,3-Alt CalixPr) has been prepared and used for the separation of di- and trisubstituted aromatic positional isomers by HPLC. The effect of organic modifier content, pH and column temperature on retention and selectivity of the benzene derivatives were studied. The retention mechanism was also discussed. The results indicated that the stationary phase behaves like a reversed-phase packing. However inclusion, hydrophobic, hydrogen bonding and pi-pi interactions seem to be involved in separation process.
authors.affiliation: Department of Organic Chemistry, Gdansk University of Technology, Narutowicza 11/12, 80-952 Gdańsk, Poland. pestka@chem.pg.gda.pl
authors.forename: Magdalena
authors.initials: M
authors.lastname: Sliwka-Kaszyńska
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Jaszczołt
authors.forename: Dariusz
authors.initials: D
authors.lastname: Witt
authors.forename: Janusz
authors.initials: J
authors.lastname: Rachoń
mesh_terms: D047250:Calixarenes / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D007536:Isomerism; D058428:Silica Gel; D012822:Silicon Dioxide / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: C498313:1,3-alternate 25,27-dipropoxy-26,28-bis-(3-propyloxy)-calix(4)arene; D047250:Calixarenes; D058428:Silica Gel; D012822:Silicon Dioxide