Chromosome-encoded CTX-M-3 from Kluyvera ascorbata: a possible origin of plasmid-borne CTX-M-1-derived cefotaximases.
A gene identical to plasmid-borne bla(CTX-M-3) is present in the chromosome of one Kluyvera ascorbata strain. It is associated with a structure including an inverted repeat right and an open reading frame 477-like gene probably involved in the mobilization of bla(CTX-M-3). Two other K. ascorbata strains rendered the previously described bla(KLUA-9) gene.
Rodríguez
María Margarita
MM
Cátedra de Microbiología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Power
Pablo
P
Radice
Marcela
M
Vay
Carlos
C
Famiglietti
Angela
A
Galleni
Moreno
M
Ayala
Juan A
JA
Gutkind
Gabriel
G
D004926:Escherichia coli / Q000235:genetics; D007525:Isoelectric Focusing; D044086:Kluyvera / Q000201:enzymology* / Q000235:genetics*; D008969:Molecular Sequence Data; D016366:Open Reading Frames / Q000235:genetics; D010957:Plasmids / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics*
C071167:beta-lactamase CTX-2; C417271:beta-lactamase CTX-M-3; D001618:beta-Lactamases