title: [Slow-release transdermal fentanyl used as anesthesia aided drug in ESS operation].
abstract: OBJECTIVE
  To observe the safety of slow-release transdermal fentanyl (TDF) used as anesthesia aided drug in endoscopic sinus surgery (ESS) peri-operation.
  
  
  METHODS
  In 30 cases of ESS operation, we observed their blood pressure, pulse and degree of blood oxygen saturation (SpO2%) before the TDF patch used and 10 min, 20 min, 30 min, 60 min after the patch used, their results were compared in respective. We observed the morbidity rate of patients accompanied with nausea, vomiting, bad appetite, skin reaction and vertigo at the same time.
  
  
  RESULTS
  There were no significant difference of blood pressure before and after the patch used, and so were the pulse and SpO2%. There were no patients accompanied with vomiting, vertigo and skin reaction. Four cases accompanied with nausea and bad appetite.
  
  
  CONCLUSIONS
  TDF is a safe, effective and convenient anesthesia aided drug in ESS peri-operation.
authors.affiliation: Department of Otorhinolaryngology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
authors.forename: Hongtao
authors.initials: H
authors.lastname: Zhen
authors.forename: Qixue
authors.initials: Q
authors.lastname: Gao
authors.forename: Jun
authors.initials: J
authors.lastname: Xu
authors.forename: Yonghua
authors.initials: Y
authors.lastname: Cui
authors.forename: Hanqi
authors.initials: H
authors.lastname: Chu
mesh_terms: D000279:Administration, Cutaneous; D000293:Adolescent; D000328:Adult; D000368:Aged; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000009:adverse effects; D000758:Anesthesia; D002648:Child; D004724:Endoscopy; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D009668:Nose Diseases / Q000601:surgery*; D011300:Preoperative Care
chemical_list: D000701:Analgesics, Opioid; D005283:Fentanyl