title: [Acute complications in sickle cell disease].
abstract: Sickle cell disease is an inherited disease characterised by the presence of an abnormal haemoglobin. Sickle cell disease can be complicated by acute vaso-occlusive crisis, which are the major clinical problem prompting admission to hospital and the major cause of death. It mainly manifests by osteo-articular pain and acute chest syndrome and can be complicated by multi-organ failure. The main treatment of severe acute vaso-occlusive crisis is based on transfusion.
authors.affiliation: Service de médecine interne, unité des maladies génétiques du globule rouge et d'aphérèse, CHU Henri Mondor, 94010 Créteil. anoosha.habibi@hmn.ap-hop-paris.fr
authors.forename: Anoosha
authors.initials: A
authors.lastname: Habibi
authors.forename: Dora
authors.initials: D
authors.lastname: Bachir
authors.forename: Bertrand
authors.initials: B
authors.lastname: Godeau
mesh_terms: D000208:Acute Disease; D000755:Anemia, Sickle Cell / Q000150:complications*; D001157:Arterial Occlusive Diseases / Q000209:etiology* / Q000628:therapy*; D001803:Blood Transfusion; D006801:Humans; D009102:Multiple Organ Failure / Q000209:etiology; D010146:Pain / Q000209:etiology; D013577:Syndrome