Neuronal network formation in human cerebral cortex.
Knowledge of the development of structural and functional connectivity in the human brain is of great fundamental and practical importance, but is largely lacking. In this review qualitative and quantitative data are presented on the formation of dendrites, axons and synapses in different regions of the human cerebral cortex from prenatal life until adulthood. This information is compiled to provide baseline information for comparison of similar data derived from postmortem brains of persons with developmental brain disorders. In addition, some data are provided on the influence of the sensory environment on cortical network formation in animals.
Ramakers
Ger J A
GJ
Neurons and Networks, Netherlands Institute for Brain Research, Meibergdreef 33, 1105 AZ Amsterdam ZO, The Netherlands. G.Ramakers@nih.knaw.nl
D002540:Cerebral Cortex / Q000254:growth & development*; D006801:Humans; D009415:Nerve Net / Q000254:growth & development*; D009473:Neuronal Plasticity