title: [Effects of a physical training program on quantitative neurological indices in mild stage type 2 spinocerebelar ataxia patients].
abstract: BACKGROUND
  Type 2 spinocerebelar ataxia (SCA2) is a neurodegenerative disease with higher prevalence and incidence in Holguín province, Cuba. At present, there is not any drug to counteract the loss of coordinative motor capacities of these patients. Thus physical training seems to be the only way to attenuate the course of disease.
  
  
  OBJECTIVE
  To evaluate the effectiveness of a physical training program on quantitative neurological indices in SCA2 patients.
  
  
  METHODS
  A samples of 87 SCA2 patients were studied. All subjects underwent a six month physical exercise program based on coordination, balance and muscular conditioning exercises. Quantitative tests were applied to all patients both before and after the application of the exercise program. Comparisons between pretest versus posttest values were made to evaluate the improvement in neurological indices.
  
  
  RESULTS
  All neurological indices both with open eyes and closed eyes significantly improved from pretest to posttest. Static balance, evaluated by Romberg test, also enhanced with training.
  
  
  CONCLUSIONS
  The exercise training program significantly improved the neurological indices in SCA2 patient with mild stage of disease.
authors.affiliation: Clínica para la Investigación y Rehabilitación de las Ataxias Hereditarias (CIRAH) Carlos J Finlay, Holguín, Cuba. ilbedi@cristal.hlg.sld.cu
authors.forename: I
authors.initials: I
authors.lastname: Pérez-Avila
authors.forename: J A
authors.initials: JA
authors.lastname: Fernández-Vieitez
authors.forename: E
authors.initials: E
authors.lastname: Martínez-Góngora
authors.forename: R
authors.initials: R
authors.lastname: Ochoa-Mastrapa
authors.forename: M G
authors.initials: MG
authors.lastname: Velázquez-Manresa
mesh_terms: D000328:Adult; D005081:Exercise Therapy; D006801:Humans; D008875:Middle Aged; D009483:Neuropsychological Tests; D020754:Spinocerebellar Ataxias / Q000473:pathology / Q000503:physiopathology / Q000628:therapy