title: [Anastrozole-resistant breast cancer responsive to exemestane--a case report].
abstract: We describe a postmenopausal woman suffering from advanced breast cancer with pleural effusion. She had prior anastrozole therapy, and was referred to our hospital with dyspnea. The use of exemestane, a highly selective steroidal aromatase inhibitor (25 mg daily), successfully induced remission of pleural effusion. Exemestane is a useful treatment for postmenopausal woman with advanced breast cancer, which is refractory to anastrozole.
authors.affiliation: First Dept. of Surgery, Wakayama Medical University.
authors.forename: Teruhisa
authors.initials: T
authors.lastname: Sakurai
authors.forename: Shoji
authors.initials: S
authors.lastname: Oura
authors.forename: Issei
authors.initials: I
authors.lastname: Hirai
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Tanino
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Yoshimas
authors.forename: Yozo
authors.initials: Y
authors.lastname: Kokawa
authors.forename: Munehiro
authors.initials: M
authors.lastname: Nishida
authors.forename: Rie
authors.initials: R
authors.lastname: Sasaki
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kinoshita
authors.forename: Toshiya
authors.initials: T
authors.lastname: Bessho
authors.forename: Hiroya
authors.initials: H
authors.lastname: Yokochi
authors.forename: Osamu
authors.initials: O
authors.lastname: Nishimura
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Okamura
mesh_terms: D000368:Aged; D000077384:Anastrozole; D000730:Androstadienes / Q000627:therapeutic use*; D047072:Aromatase Inhibitors / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000188:drug therapy* / Q000473:pathology; D019008:Drug Resistance, Neoplasm; D005260:Female; D006801:Humans; D009570:Nitriles / Q000494:pharmacology*; D017698:Postmenopause; D014230:Triazoles / Q000494:pharmacology*
chemical_list: D000730:Androstadienes; D047072:Aromatase Inhibitors; D009570:Nitriles; D014230:Triazoles; D000077384:Anastrozole; C056516:exemestane