title: [Polymorphic analysis of four Y short tandem repeat loci in Han nationality of Hebei province in China].
abstract: OBJECTIVE
  To investigate the distribution of the polymorphism of the Y-chromosomal loci DYS438, DYS439, GATA A7.1 and GATA A7.2 among Han population in Hebei province.
  
  
  METHODS
  With the use of PCR followed by polyacrylamide gel electrophoresis and silver staining, the allele frequencies of these loci in 164 unrelated men of Han population were investigated.
  
  
  RESULTS
  Four, five, five, four alleles were observed at the loci DYS438, DYS439, GATA A7.1 and GATA A7.2 respectively; the frequencies of these alleles ranged from 0.0359 to 0.6587, from 0.0179 to 0.4107, from 0.0122 to 0.4146 and from 0.0476 to 0.5238 respectively; the probability discrimination of these loci were 0.5121, 0.6811, 0.6679 and 0.6327 respectively. Seventy different haplotypes were found at these loci. Thirty-six different haplotypes appeared only once. The power of discrimination of these four loci was 0.9480.
  
  
  CONCLUSIONS
  The results demonstrate that these loci(DYS438, DYS439, GATA A7.1 and GATA A7.2) are good genetic markers with high determination power and can be applied to individual identification, especially in paternity test and the detection of mixed samples.
authors.affiliation: Department of Forensic Medicine, Hebei Medical University, Shijiazhuang, Hebei, 050017 P. R. China.
authors.forename: Li
authors.initials: L
authors.lastname: Zhao
authors.forename: Yu-xia
authors.initials: YX
authors.lastname: Yao
authors.forename: Bin
authors.initials: B
authors.lastname: Cong
authors.forename: Li-hong
authors.initials: LH
authors.lastname: Fu
authors.forename: Zhen-yong
authors.initials: ZY
authors.lastname: Gu
authors.forename: Shu-jin
authors.initials: SJ
authors.lastname: Li
authors.forename: Min
authors.initials: M
authors.lastname: Zuo
authors.forename: Guo-zhong
authors.initials: GZ
authors.lastname: Zhang
mesh_terms: D000483:Alleles; D044466:Asian People / Q000235:genetics*; D002681:China / Q000208:ethnology; D041322:Chromosomes, Human, Y; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D005838:Genotype; D006239:Haplotypes; D006801:Humans; D008297:Male; D010334:Paternity; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences / Q000235:genetics*
chemical_list: D005819:Genetic Markers