title: Current practice in managing patients on anticoagulants and/or antiplatelet agents around the time of gastrointestinal endoscopy -- a nation-wide survey in Germany.
abstract: Anticoagulants and antiplatelet agents are widely used in the prophylaxis and management of thromboembolic and cardiovascular diseases. Gastrointestinal bleeding is a well-known complication of these agents. Modification of anticoagulant and antiplatelet therapy is often required in patients undergoing surgical procedures and specific recommendations for the perioperative period have been issued. Fewer data exist with regard to the use of these agents around the time of endoscopic procedures. A survey of the American Society for Gastrointestinal Endoscopy (ASGE), performed several years ago, showed a wide variation between endoscopists in the management of anticoagulants and antiplatelet agents in the periendoscopic period. Subsequently, guidelines have been proposed by the ASGE as well as the German Society for Gastroenterology (DGVS). The aim of this study was to investigate the current practices among German endoscopists regarding the use of these medications in patients undergoing endoscopic procedures and to assess their adherence to published guidelines. Our data demonstrate that, in spite of the dissemination of guidelines, there is still a wide variation in the periendoscopic management of patients who are at increased risk for bleeding due to anticoagulants, especially in patients taking antiplatelet agents.
authors.affiliation: I. Medizinische Klinik und Poliklinik der Johannes-Gutenberg-Universität Mainz, Germany. patrick.mosler@web.de
authors.forename: P
authors.initials: P
authors.lastname: Mosler
authors.forename: K
authors.initials: K
authors.lastname: Mergener
authors.forename: U
authors.initials: U
authors.lastname: Denzer
authors.forename: R
authors.initials: R
authors.lastname: Kiesslich
authors.forename: P R
authors.initials: PR
authors.lastname: Galle
authors.forename: S
authors.initials: S
authors.lastname: Kanzler
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage* / Q000009:adverse effects; D001780:Blood Coagulation Tests; D016099:Endoscopy, Gastrointestinal; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced / Q000517:prevention & control; D005858:Germany; D019983:Guideline Adherence / Q000706:statistics & numerical data; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage* / Q000009:adverse effects; D012306:Risk; D011795:Surveys and Questionnaires
chemical_list: D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors