A review of the current use of magnetic resonance imaging in pregnancy and safety implications for the fetus.
This paper presents an overview of the application of and risks of exposure to Magnetic Resonance Imaging (MRI) in pregnancy. It reviews the risks to the fetus by considering the hazards in terms of the three main components of an MRI system. These are the static magnetic field, the time-varying magnetic gradient fields and the pulsed radio frequency fields. The hazards discussed are biological effects, miscarriage, heating effects and acoustic noise exposure. This paper also presents a survey of MRI sites within the United Kingdom to ascertain the extent of MRI usage in pregnancy. To validate the situation of MRI in pregnancy a survey was sent to 352 MR units throughout the United Kingdom. The questions were grouped to assess (a) maternal MRI diagnosis (b) fetal MRI and (c) work practices for pregnant MRI staff. The results showed that 91% of sites were imaging pregnant women in need of diagnosis in the second and third trimester. This paper highlights that MRI can add information for fetal central nervous system abnormalities identified by ultrasound screening, however within the UK direct fetal imaging was only performed in 8% of sites. This paper indicates the need for research to be undertaken for specific MRI clinical conditions. It also advises that risk assessment for pregnant staff working in MRI is performed, and that there is a clear need for further research into the effects of MRI in pregnancy as there is a need for clear authoritive advice.
De Wilde
J P
JP
Department of Bioengineering, Bagrit Centre, Imperial College, Exhibition Road, South Kensington, London SW7 2 AZ, UK. j.dewilde@imperial.ac.uk
Rivers
A W
AW
Price
D L
DL
D002490:Central Nervous System / Q000528:radiation effects*; D004574:Electromagnetic Fields / Q000009:adverse effects*; D005260:Female; D005333:Fetus / Q000528:radiation effects*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000009:adverse effects*; D011247:Pregnancy