Sequence variants in the 3'-->5' deoxyribonuclease TREX2: identification in a genetic screen and effects on catalysis by the recombinant proteins.
Perrino
Fred W
FW
Department of Biochemistry, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA.
Krol
Anna
A
Harvey
Scott
S
Zheng
S Lilly
SL
Horita
David A
DA
Hollis
Thomas
T
Meyers
Deborah A
DA
Isaacs
William B
WB
Xu
Jianfeng
J
D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D005090:Exodeoxyribonucleases / Q000235:genetics* / Q000378:metabolism; D014644:Genetic Variation; D006801:Humans; D007700:Kinetics; D008297:Male; D010750:Phosphoproteins / Q000235:genetics* / Q000378:metabolism; D016133:Polymerase Chain Reaction; D020641:Polymorphism, Single Nucleotide; D011471:Prostatic Neoplasms / Q000201:enzymology; D011994:Recombinant Proteins / Q000378:metabolism; D012016:Reference Values
D010750:Phosphoproteins; D011994:Recombinant Proteins; D005090:Exodeoxyribonucleases; C486104:TREX2 protein, human