title: Urinary methylxanthine and autistic disorder: absence of previously reported correlation.
abstract: We were unable to reveal significant difference in the levels of xanthine and methylxanthines in the urine samples from 59 patients diagnosed with autistic symptoms and 64 age- and sex-matched normal volunteers. Our data suggest that abnormalities in xanthine and methylxanthine excretion (US Patent 20020019406 A1, Feb. 12, 2002) represent distincly uncommon symptoms in autism.
authors.affiliation: Department of Gynecology, Perinatology and Child Health, University of Roma La Sapienza, Roma, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Salerno
authors.forename: C
authors.initials: C
authors.lastname: Crifò
mesh_terms: D001321:Autistic Disorder / Q000652:urine*; D016022:Case-Control Studies; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006801:Humans; D008297:Male; D013053:Spectrophotometry; D013805:Theobromine / Q000652:urine; D013997:Time Factors; D014665:Vasodilator Agents / Q000652:urine; D014970:Xanthines / Q000652:urine*
chemical_list: D014665:Vasodilator Agents; D014970:Xanthines; C008514:methylxanthine; D013805:Theobromine