title: Design and evaluation of a Dean vortex-based micromixer.
abstract: A mixer, based on the Dean vortex, is fabricated and tested in an on-chip format. When fluid is directed around a curve under pressure driven flow, the high velocity streams in the center of the channel experience a greater centripetal force and so are deflected outward. This creates a pair of counter-rotating vortices moving fluid toward the inner wall at the top and bottom of the channel and toward the outer wall in the center. For the geometries studied, the vortices were first seen at Reynolds numbers between 1 and 10 and became stronger as the flow velocity is increased. Vortex formation was monitored in channels with depth/width ratios of 0.5, 1.0, and 2.0. The lowest aspect ratio strongly suppressed vortex formation. Increasing the aspect ratio above 1 appeared to provide improved mixing. This design has the advantages of easy fabrication and low surface area.
authors.affiliation: Center for Bio/Molecular Science and Engineering, Naval Research Laboratory, Washington DC 20375-5348, USA.
authors.forename: Peter B
authors.initials: PB
authors.lastname: Howell
authors.forename: David R
authors.initials: DR
authors.lastname: Mott
authors.forename: Joel P
authors.initials: JP
authors.lastname: Golden
authors.forename: Frances S
authors.initials: FS
authors.lastname: Ligler
mesh_terms: D002498:Centrifugation / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods; D044085:Microfluidics / Q000295:instrumentation* / Q000379:methods; D008904:Miniaturization; D009038:Motion