title: Mediators of blood-brain barrier disruption and potential therapeutic interventions for protection of the barrier following focal ischemia.
authors.affiliation: Department of Neurological Surgery, Cleveland Clinic Foundation, Ohio, USA.
authors.forename: Stephen N
authors.initials: SN
authors.lastname: Ponnampalam
authors.forename: Marc R
authors.initials: MR
authors.lastname: Mayberg
mesh_terms: D042682:Angiopoietins / Q000378:metabolism; D000818:Animals; D001812:Blood-Brain Barrier / Q000502:physiology*; D002545:Brain Ischemia / Q000201:enzymology / Q000503:physiopathology* / Q000628:therapy*; D002199:Capillary Permeability / Q000502:physiology; D003300:Copper / Q000378:metabolism; D007036:Hypothermia, Induced / Q000379:methods; D018799:Intercellular Adhesion Molecule-1 / Q000378:metabolism; D007375:Interleukin-1 / Q000378:metabolism; D007962:Leukocytes / Q000378:metabolism; D061965:Matrix Metalloproteinase Inhibitors; D020782:Matrix Metalloproteinases / Q000378:metabolism; D051379:Mice; D051381:Rats; D019087:Selectins / Q000378:metabolism; D013482:Superoxide Dismutase / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism; D015032:Zinc / Q000378:metabolism
chemical_list: D042682:Angiopoietins; D007375:Interleukin-1; D061965:Matrix Metalloproteinase Inhibitors; D019087:Selectins; D014409:Tumor Necrosis Factor-alpha; D042461:Vascular Endothelial Growth Factor A; D018799:Intercellular Adhesion Molecule-1; D003300:Copper; D013482:Superoxide Dismutase; D020782:Matrix Metalloproteinases; D015032:Zinc