title: Multiple sclerosis and celiac disease: is there an increased risk?
abstract: Multiple sclerosis and celiac disease are both considered immune-mediated diseases. Recently, improved serological screening methods provided a higher prevalence of celiac disease (CD) in the general population worldwide and also demonstrated gastrointestinal symptoms may be lacking. The aim of this study was to determine the prevalence of (CD) in an unselected group of 95 adults with multiple sclerosis using transglutaminase antibodies. No patients showed pathological values. Different immune and genetic basis between the two diseases may represent crucial insights to explain our results.
authors.affiliation: Clinica Pediatrica, Università dell'Insubria, Varese, Italy. silvisa@tin.it
authors.forename: S
authors.initials: S
authors.lastname: Salvatore
authors.forename: S
authors.initials: S
authors.lastname: Finazzi
authors.forename: A
authors.initials: A
authors.lastname: Ghezzi
authors.forename: A
authors.initials: A
authors.lastname: Tosi
authors.forename: A
authors.initials: A
authors.lastname: Barassi
authors.forename: C
authors.initials: C
authors.lastname: Luini
authors.forename: B
authors.initials: B
authors.lastname: Bettini
authors.forename: A
authors.initials: A
authors.lastname: Zibetti
authors.forename: L
authors.initials: L
authors.lastname: Nespoli
authors.forename: G V
authors.initials: GV
authors.lastname: Melzi d'Eril
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000097:blood; D002446:Celiac Disease / Q000453:epidemiology* / Q000276:immunology*; D006801:Humans; D008875:Middle Aged; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000453:epidemiology* / Q000276:immunology*; D015995:Prevalence; D012307:Risk Factors; D011503:Transglutaminases / Q000276:immunology
chemical_list: D001323:Autoantibodies; D011503:Transglutaminases