title: [Value of transvaginal color Doppler flow imaging conjugated with multiple serum tumor markers in diagnosis of ovarian tumors].
abstract: OBJECTIVE
  To investigate the value of trasvaginal color Doppler flow imaging (TV-CDFI ) in combination with multiple serum tumor markers in the diagnosis of ovarian tumors.
  
  
  METHODS
  A total of 74 patients with pelvic masses ( 30 cases with benign tumors, 44 cases with malignant tumors) were examined by TV-CDFI and the level of 7 serum tumor markers was also measured at same time. The above results were compared with the pathologic findings.
  
  
  RESULTS
  The diagnostic accuracy for the TV-CDFI only, and 7 serum tumor markers measured were 90.5% and 59.5% respectively. If TV-CDFI combined with multiple serum tumor marker measurements, the diagnostic accuracy of 98.6% was achieved, whereby it was 97.7% for malignant tumors.
  
  
  CONCLUSIONS
  TV-CDFI allows the diagnosis and differential diagnosis of the majority of ovarian tumors, particularly in part of ovarian carcinoma at early stage. Combined with multiple serum tumor marker measurements, this method can improve diagnostic sensitivity and specificity,hence it facilitates the early diagnosis and differential diagnosis.
authors.affiliation: Department of Ultrasound, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, 510060 P.R.China. gz-wangyue@yahoo.com.cn
authors.forename: Yue
authors.initials: Y
authors.lastname: Wang
authors.forename: Long-Zhong
authors.initials: LZ
authors.lastname: Liu
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Zhou
authors.forename: Xiao-Qing
authors.initials: XQ
authors.lastname: Pei
authors.forename: Xiao-Yue
authors.initials: XY
authors.lastname: Chen
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000000981:diagnostic imaging; D000293:Adolescent; D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood*; D018284:Cystadenocarcinoma, Serous / Q000097:blood / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000097:blood / Q000000981:diagnostic imaging*; D013724:Teratoma / Q000097:blood / Q000000981:diagnostic imaging*; D018615:Ultrasonography, Doppler, Color
chemical_list: D014408:Biomarkers, Tumor