title: Reflections on the landmark studies of beta-carotene supplementation.
authors.forename: Anna J
authors.initials: AJ
authors.lastname: Duffield-Lillico
authors.forename: Colin B
authors.initials: CB
authors.lastname: Begg
mesh_terms: D000818:Animals; D016588:Anticarcinogenic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D000975:Antioxidants / Q000008:administration & dosage* / Q000009:adverse effects; D002273:Carcinogens / Q000008:administration & dosage / Q000009:adverse effects*; D002318:Cardiovascular Diseases / Q000401:mortality; D002986:Clinical Trials as Topic; D019587:Dietary Supplements; D004195:Disease Models, Animal; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008168:Lung / Q000187:drug effects / Q000378:metabolism; D008175:Lung Neoplasms / Q000139:chemically induced* / Q000453:epidemiology* / Q000209:etiology / Q000378:metabolism / Q000517:prevention & control; D008297:Male; D016877:Oxidants / Q000008:administration & dosage / Q000009:adverse effects*; D016032:Randomized Controlled Trials as Topic; D018570:Risk Assessment; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D014481:United States / Q000453:epidemiology; D019207:beta Carotene / Q000008:administration & dosage* / Q000009:adverse effects*
chemical_list: D016588:Anticarcinogenic Agents; D000975:Antioxidants; D002273:Carcinogens; D016877:Oxidants; D019207:beta Carotene