[Inappropriate combinations of antiretroviral drugs].
At present 19 antiretroviral drugs are available, which offer together 969 possible triple-combinations. Only a few combinations, mainly of nucleoside inhibitors of reverse transcriptase, are contraindicated due to undesirable interactions, which may negatively influence the treatment efficacy or increase toxicity. With raising number of antiretroviral drugs there must also be paid more attention to possible interactions of these drugs.
Machala
Ladislav
L
Clinic of Infectious Diseases, Faculty Hospital Bulovka, Budínova 2, 180-81 Prague 8, Czech Republic. ladimachala@hotmail.com
Cerný
Rudolf
R
D044966:Anti-Retroviral Agents / Q000008:administration & dosage* / Q000009:adverse effects; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D015658:HIV Infections / Q000188:drug therapy; D006801:Humans
D044966:Anti-Retroviral Agents