title: Pleural cryptococcosis with idiopathic CD4 positive T-lymphocytopenia.
abstract: A 19-year-old man was admitted to our hospital because of chest pain. He was diagnosed as having pleural cryptococcosis by pleural biopsy. His CD4 positive T-lymphocyte count was low (< 300 microl) and there was no evidence of human immunodeficiency virus infection. He was successfully treated with fluconazole. However, his CD4 positive lymphocyte counts remained low after the recovery and he was diagnosed as idiopathic CD4 positive T-lymphocytopenia. Pleural cryptococcosis is rare and its predisposing condition is still controversial. To our knowledge, this is the first case of pleural cryptococcosis associated with idiopathic CD4 positive T lymphocytopenia.
authors.affiliation: Third Department of Internal Medicine, Kagoshima University Faculty of Medicine, Sakuragaoka 8-35-1, Kagoshima 890-8520.
authors.forename: Takashi
authors.initials: T
authors.lastname: Kawabata
authors.forename: Wataru
authors.initials: W
authors.lastname: Matsuyama
authors.forename: Ikkou
authors.initials: I
authors.lastname: Higashimoto
authors.forename: Yoshifusa
authors.initials: Y
authors.lastname: Koreeda
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Eiraku
authors.forename: Masaharu
authors.initials: M
authors.lastname: Kawabata
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Osame
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D002637:Chest Pain / Q000209:etiology; D003453:Cryptococcosis / Q000150:complications* / Q000628:therapy; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010994:Pleura / Q000187:drug effects / Q000382:microbiology / Q000473:pathology; D010995:Pleural Diseases / Q000150:complications* / Q000175:diagnosis; D011379:Prognosis; D018344:T-Lymphocytopenia, Idiopathic CD4-Positive / Q000150:complications* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole