[Antimicrobial photodynamic therapy for prevention of alveolar ostitis and post-extraction pain].
OBJECTIVE
Alveolar ostitis occurs with an incidence of 3-25% after tooth extraction. Antimicrobial photodynamic therapy (aPDT) with HELBO Blue and TheraLite laser enables local decontamination of the extraction socket. The aim of the study was to evaluate the possibility of aPDT with HELBO Blue and diode soft laser to reduce the prevalence of alveolar ostitis.


METHODS
In an intraindividual study with 100 patients in 130 jaws, one or multiple contralateral teeth were removed at 1-week intervals. Randomly each side was treated with or without aPDT with a standardized protocol. At recall the evaluation of the extraction socket was performed by the investigator and the postoperative pain sensation was judged by the patient on an analog pain scale (0-100).


RESULTS
In the group with aPDT alveolar ostitis occurred at one extraction site and in the control group without aPDT in 13 cases. The subjective pain assessment on the day after tooth removal was scored with 11.2+/-9.8 in the aPDT-group and with 19.0+/-12.2 in the control group. One week after extraction the pain sensation in the aPDT group was scored with 2.4+/-9.2 and in the control group with 13.1+/-25.2. The difference was significantly lower with p=0.000 for the 1st and 8th post-surgical days in the aPDTgroup.


CONCLUSIONS
The significantly lower incidence of alveolar ostitis after antimicrobial photodynamic therapy seems to be a new and promising possibility for the prevention of alveolar ostitis.
Neugebauer
J
J
Klinik und Poliklinik für Zahnärztliche Chirurgie und Mund-, Kiefer- und Plastische Gesichtschirurgie, Universität zu Köln. Joerg.neugebauer@medizin.uni-koeln.de
Jozsa
M
M
Kübler
A
A
D001424:Bacterial Infections / Q000517:prevention & control*; D003131:Combined Modality Therapy; D004368:Dry Socket / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D010147:Pain Measurement; D010149:Postoperative Pain / Q000209:etiology / Q000517:prevention & control*; D010778:Photochemotherapy; D011182:Postoperative Care; D012307:Risk Factors; D014081:Tooth Extraction / Q000009:adverse effects*; D020390:Tooth Socket / Q000382:microbiology*; D014945:Wound Healing / Q000187:drug effects