title: Effect of arousal methods for 175 cases of prolonged coma after severe traumatic brain injury and its related factors.
abstract: OBJECTIVE
  To determine the effect of arousal methods for prolonged coma of 175 patients with severe traumatic brain injury and related factors.
  
  
  METHODS
  There were 175 cases with persistent coma longer than 1 month after severe traumatic brain injury. Coma lasted 1-12 months. Arousal procedures included hyperbaric oxygen, physical therapy and arousal drugs.
  
  
  RESULTS
  In the 175 prolonged coma patients 110 got recovery of consciousness; in 118 cases with coma of 1-3 months, 86 cases recovered consciousness (72.9%); in 42 cases with coma of 4-6 months, 20 cases recovered consciousness (47.6); and in 15 cases with coma of longer than 6 months, only 4 cases recovered consciousness (26.7%). The recovery of consciousness depended on patient's primary brain stem damage, cerebral hernia, GCS score, and age.
  
  
  CONCLUSIONS
  Application of appropriate arousal procedures improves recovery of consciousness in patients with prolonged coma.
authors.affiliation: Department of Neurosurgery, Renji Hospital, Shanghai Second Medical University, Shanghai 200001, China. jiangjyb@online.sh.cn
authors.forename: Ji-Yao
authors.initials: JY
authors.lastname: Jiang
authors.forename: Ying-Hui
authors.initials: YH
authors.lastname: Bo
authors.forename: Yu-Hua
authors.initials: YH
authors.lastname: Yin
authors.forename: Yao-Hua
authors.initials: YH
authors.lastname: Pan
authors.forename: Yu-Min
authors.initials: YM
authors.lastname: Liang
authors.forename: Qi-Zhong
authors.initials: QZ
authors.lastname: Luo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001930:Brain Injuries / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D020207:Coma, Post-Head Injury / Q000628:therapy*; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D008297:Male; D008875:Middle Aged; D020127:Recovery of Function; D016896:Treatment Outcome