title: [The role of emotions in psychopathology].
abstract: OBJECTIVE
  In the present study, functional fMRI was used to test the influence of induced emotions on a non-affective, attention-demanding, cognitive task.
  
  
  METHODS
  Twelve healthy males viewed blocks of affective pictures. Between picture presentation a Simon-paradigm was presented. In an alternating way blocks with stimulus-response compatible and incompatible trials were presented.
  
  
  RESULTS
  Emotion induction differentially influenced cortical activation patterns. In negative mood incompatible trials in contrast to compatible trials lead to significant decrease of activity in emotion related brain areas like the amygdala, the hippocampus and the medial prefrontal cortex.
  
  
  CONCLUSIONS
  These results support the hypothesis that negative emotions increase the information processing load and drain attentional resources. To compensate these effects emotion related brain areas must attenuate their activity.
authors.affiliation: Klinik für Psychiatrie und Psychotherapie der Universität Regensburg am Bezirksklinikum. monika.sommer@medbo.de
authors.forename: Monika
authors.initials: M
authors.lastname: Sommer
authors.forename: Jürgen
authors.initials: J
authors.lastname: Müller
authors.forename: Tatjana
authors.initials: T
authors.lastname: Weber
authors.forename: Göran
authors.initials: G
authors.lastname: Hajak
mesh_terms: D000328:Adult; D000339:Affect / Q000502:physiology*; D000679:Amygdala / Q000503:physiopathology; D001143:Arousal / Q000502:physiology; D001288:Attention / Q000502:physiology*; D001921:Brain / Q000503:physiopathology*; D004644:Emotions / Q000502:physiology*; D006624:Hippocampus / Q000503:physiopathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000503:physiopathology*; D010364:Pattern Recognition, Visual / Q000502:physiology; D017397:Prefrontal Cortex / Q000503:physiopathology; D011930:Reaction Time / Q000502:physiology; D012016:Reference Values