title: [Evolution of lung cancer in the North of the province of Castellón, Spain, 1993-2002].
abstract: OBJECTIVE
  To investigate the changes in lung cancer incidence, histological type, and survival in patients in the north of the province of Castellón, Spain, during a follow-up period of 10 years, and to compare the findings with other national and international studies.
  
  
  METHODS
  All patients diagnosed with lung cancer between January 1, 1993 and December 31, 2002 were included in this prospective, observational study. Disease was confirmed by biopsy or suspected from clinical, radiological, and/or bronchoscopic findings.
  
  
  RESULTS
  In the study period, 271 patients were diagnosed with lung cancer (239 men and 32 women), with a mean (SD) age of 66.8 (11.8) years. The age-adjusted incidence rate standardized to the world population was 20.42 cases per 100,000 population. Smokers or ex-smokers comprised 88.1% of the study population, and 72.6% of patients were over 60 years old. Biopsy confirmation was obtained in 262 cases (96.7%). Squamous cell carcinoma predominated (46.5%) but the proportion of adenocarcinoma increased (23.6%). Surgery was possible in only 22% of the patients. Mean overall 5-year survival was 15.7 months.
  
  
  CONCLUSIONS
  In the north of the province of Castellón, the incidence of lung cancer continues to increase in men but has decreased slightly in women. Squamous cell carcinoma is the most common type, but the incidence of adenocarcinoma has clearly increased. Overall, survival did not improve during the 10 years of follow up despite advances in treatment.
authors.affiliation: Unidad de Neumología, Servicio de Medicina Interna, Hospital Comarcal de Vinaroz, Vinaroz, Castellón, Spain. miravet_lui@gva.es
authors.forename: L
authors.initials: L
authors.lastname: Miravet
authors.forename: A
authors.initials: A
authors.lastname: Paradís
authors.forename: S
authors.initials: S
authors.lastname: Peláez
authors.forename: M
authors.initials: M
authors.lastname: Arnal
authors.forename: F
authors.initials: F
authors.lastname: Cabadés
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D001984:Bronchial Neoplasms / Q000401:mortality* / Q000473:pathology* / Q000628:therapy; D001999:Bronchoscopy; D002294:Carcinoma, Squamous Cell / Q000401:mortality* / Q000473:pathology* / Q000628:therapy; D002391:Catchment Area, Health; D003131:Combined Modality Therapy; D018450:Disease Progression; D005260:Female; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000401:mortality* / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012907:Smoking / Q000453:epidemiology; D013030:Spain / Q000453:epidemiology; D015996:Survival Rate