Acinic cell carcinoma: an unusual cause of bronchial obstruction in a child.
Primary acinic cell carcinomas of the lung are rare tumors, usually presenting in adulthood as parenchymal or endobronchial masses. These lesions are generally recognized by their morphological pattern and the presence of periodic acid-Schiff (PAS)-positive, diastase-resistant cytoplasmic granules. We describe a case of pri-mary acinic cell carcinoma of the bronchus in a 4-year-old girl. The tumor has the typical acinar structures:weakly PAS-positive, diastase-resistant cytoplasmic granules and intra-acinar laminated calcific structures. A lobectomy was done with a clear bronchial resection margin. The child is well with no evidence of recurrence or metastasis 2 years postresection.
Sabaratnam
Rathi M
RM
Department of Anatomical Pathology, Neson R. Mandela School of Medicine, University of KwaZulu-Natal, Congella, Durban, South Africa.
Anunathan
Redi
R
Govender
Dhirendra
D
D000402:Airway Obstruction / Q000209:etiology*; D018267:Carcinoma, Acinar Cell / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D002283:Carcinoma, Bronchogenic / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008168:Lung / Q000648:ultrastructure; D008175:Lung Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D046529:Microscopy, Electron, Transmission; D010503:Periodic Acid-Schiff Reaction; D022142:Secretory Vesicles / Q000648:ultrastructure