Meta-analysis of randomized controlled trials on hydrocolloid occlusive dressing versus conventional gauze dressing in the healing of chronic wounds.
Chronic wound management is a difficult area in surgical practice. A wide range of dressings have been recommended for the management of chronic wounds. The present meta-analysis was undertaken to determine the effectiveness of hydrocolloid dressing (HCD) in the healing of chronic wounds compared with conventional gauze dressing. All available controlled clinical trials published before December 2001 that compared HCD to conventional gauze dressing in the healing of chronic wounds were systematically reviewed. We identified and analysed 12 randomized trials (11 published; 1 unpublished) comprising 693 patients with 819 ulcers. The overall odds ratio under the fixed effect model was 1.72, that is, 72% more ulcers healed completely with HCD than with conventional gauze dressing. This result was both clinically and statistically significant.
Singh
Aparajita
A
Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
Halder
Sajal
S
Menon
Geetha R
GR
Chumber
Sunil
S
Misra
Mahesh Chandra
MC
Sharma
Lalit Kumar
LK
Srivastava
Anurag
A
D001458:Bandages; D003102:Colloids; D003362:Cost-Benefit Analysis; D006801:Humans; D009779:Occlusive Dressings; D016017:Odds Ratio; D016032:Randomized Controlled Trials as Topic; D012306:Risk; D014945:Wound Healing
D003102:Colloids