title: An overview of the role of insulin in the treatment of hyperglycemia during acute myocardial ischemia.
abstract: Hyperglycemia on admission to the coronary care unit is associated with poor outcome. It has now been reasonably well established that intravenous insulin infusion during acute myocardial infarction has a protective role and reduces mortality. The present article reviews the current understanding of the cardioprotective effect of insulin and the recent advances in this area.
authors.affiliation: Department of Medicine, Division of Endocrinology, Dalhousie University, Halifax, Canada. ali.imran@cdha.nshealth.ca
authors.forename: S Ali
authors.initials: SA
authors.lastname: Imran
authors.forename: K
authors.initials: K
authors.lastname: Malmberg
authors.forename: Jafna L
authors.initials: JL
authors.lastname: Cox
authors.forename: Thomas Pp
authors.initials: TP
authors.lastname: Ransom
authors.forename: Ehud
authors.initials: E
authors.lastname: Ur
mesh_terms: D003325:Coronary Care Units; D003422:Critical Care / Q000379:methods; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000188:drug therapy* / Q000209:etiology / Q000401:mortality; D007262:Infusions, Intravenous; D007328:Insulin / Q000627:therapeutic use*; D008297:Male; D009203:Myocardial Infarction / Q000150:complications* / Q000175:diagnosis / Q000401:mortality; D017202:Myocardial Ischemia / Q000503:physiopathology; D011379:Prognosis; D018570:Risk Assessment; D012720:Severity of Illness Index; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D007328:Insulin