title: Cell biology. "Pumping" iron: the proteins.
authors.affiliation: Department of Molecular and Experimental Medicine, Scripps Research Institute, La Jolla, CA 92037, USA. beutler@scripps.edu
authors.forename: Ernest
authors.initials: E
authors.lastname: Beutler
mesh_terms: D000818:Animals; D023181:Antimicrobial Cationic Peptides / Q000378:metabolism*; D001692:Biological Transport; D027682:Cation Transport Proteins / Q000235:genetics / Q000378:metabolism*; D020895:Enterocytes / Q000378:metabolism; D004920:Erythropoiesis; D004921:Erythropoietin / Q000235:genetics / Q000378:metabolism; D005786:Gene Expression Regulation; D006432:Hemochromatosis / Q000235:genetics; D000071020:Hemochromatosis Protein; D022781:Hepatocytes / Q000378:metabolism; D064451:Hepcidins; D015395:Histocompatibility Antigens Class I / Q000235:genetics; D006706:Homeostasis; D007501:Iron / Q000378:metabolism*; D035941:Iron Regulatory Protein 1 / Q000378:metabolism*; D035942:Iron Regulatory Protein 2 / Q000378:metabolism*; D008565:Membrane Proteins / Q000235:genetics; D051379:Mice; D008954:Models, Biological; D009154:Mutation; D009569:Nitric Oxide / Q000378:metabolism; D010100:Oxygen / Q000502:physiology; D020218:Response Elements; D015398:Signal Transduction; D014158:Transcription, Genetic; D000098742:Ferroportin
chemical_list: D023181:Antimicrobial Cationic Peptides; D027682:Cation Transport Proteins; D000071020:Hemochromatosis Protein; D064451:Hepcidins; C499535:Hfe protein, mouse; D015395:Histocompatibility Antigens Class I; D008565:Membrane Proteins; D000098742:Ferroportin; D004921:Erythropoietin; D009569:Nitric Oxide; D007501:Iron; D035941:Iron Regulatory Protein 1; D035942:Iron Regulatory Protein 2; D010100:Oxygen