A comparative study of preload-adjusted maximal and peak power: assessment of ventricular performance in clinical practice.
This study was performed to determine whether preload-adjusted peak power can act as a surrogate for preload-adjusted maximal power in the assessment of left ventricular performance in the clinical setting. Ninety-nine consecutive patients who had undergone elective coronary artery bypass grafting were studied. Fifty-five of these patients were divided into four study groups. Afterload was changed with phenylephrine (n = 12) or glyceryl trinitrate (n = 13), preload was increased with intravenous colloid (n = 18), and contractility was increased with dobutamine (n = 12). There was excellent correlation between the two indices (r = 0.99, y = 1.0168x + 0.0769; p < 0.0001). Manipulation of neither preload nor afterload affected the indices. Both indices increased significantly during dobutamine infusion (p = 0.002). In conclusion, preload-adjusted peak power can be used as a substitute for preload-adjusted maximal power in the determination of ventricular performance in clinical practice.
Amà
R
R
Institute Biomedical Technology, Ghent University, Ghent, Belgium.
Claessens
T
T
Roosens
C
C
Segers
P
P
Verdonck
P
P
Poelaert
J
J
D002316:Cardiotonic Agents; D001026:Coronary Artery Bypass; D004280:Dobutamine; D005780:Gelatin; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D009200:Myocardial Contraction; D005996:Nitroglycerin; D010656:Phenylephrine; D011184:Postoperative Period; D015203:Reproducibility of Results; D016277:Ventricular Function, Left / Q000187:drug effects
D002316:Cardiotonic Agents; D010656:Phenylephrine; D004280:Dobutamine; D005780:Gelatin; D005996:Nitroglycerin