title: Inclusion complex formation between alpha-cyclodextrin and biodegradable aliphatic polyesters.
abstract: Inclusion complexes (ICs) between alpha-cyclodextrin (alpha-CD) and three kinds of biodegradable aliphatic polyesters with different sequence lengths of the monomeric repeating units poly(3-hydroxypropionate) [P(3HP)], poly(4-hydroxybutyrate) [P(4HB)] and poly(epsilon-caprolactone)(PCL) were prepared by mixing a solution of alpha-CD with that of the polymer, followed by stirring. The ICs were obtained as insoluble precipitates and characterized by FT-IR, WAXD and DSC. All measurements showed that the polymer chains of all three kinds of polyester were included into the alpha-CD cavity and formed ICs with different stoichiometries. WAXD patterns and thermal analysis indicated that these ICs possessed a channel structure and the crystallization of the polyester chains was suppressed upon inclusion into the alpha-CD cavity.
authors.affiliation: Department of Biomolecular Engineering, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8501, Japan.
authors.forename: Kyung-Moo
authors.initials: KM
authors.lastname: Shin
authors.forename: Tungalag
authors.initials: T
authors.lastname: Dong
authors.forename: Yong
authors.initials: Y
authors.lastname: He
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Taguchi
authors.forename: Akihiro
authors.initials: A
authors.lastname: Oishi
authors.forename: Haruo
authors.initials: H
authors.lastname: Nishida
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Inoue
mesh_terms: D001673:Biodegradation, Environmental; D002152:Calorimetry, Differential Scanning; D003460:Crystallization; D006860:Hydrogen Bonding; D046911:Macromolecular Substances; D009682:Magnetic Resonance Spectroscopy; D011091:Polyesters / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D017550:Spectroscopy, Fourier Transform Infrared; D013696:Temperature; D014961:X-Ray Diffraction; D047391:alpha-Cyclodextrins / Q000032:analysis / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism
chemical_list: D046911:Macromolecular Substances; D011091:Polyesters; D047391:alpha-Cyclodextrins; C032613:alpha-cyclodextrin