Structure determination of mycolactone C via total synthesis.
[structure: see text] By total synthesis, mycolactone C has been established as an approximately 1:1 mixture of Z-Delta4'5'- and E-Delta4'5'-geometric isomers of C12'-deoxymycolactones A and B.
Judd
Ted C
TC
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
Bischoff
Alexander
A
Kishi
Yoshito
Y
Adusumilli
Sarojini
S
Small
Pamela L C
PL
D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry*; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry*; D018942:Macrolides; D008968:Molecular Conformation; D019911:Mycobacterium ulcerans / Q000737:chemistry*
D000475:Alkenes; D007783:Lactones; D018942:Macrolides; C451488:mycolactone A; C451489:mycolactone B; C510305:mycolactone C