[A clinical study on manshuailing oral liquid in treating elder patients with congestive heart failure of type heart and kidney yang deficiency].
OBJECTIVE
To investigate the clinical effect of manshuailing oral liquid on patients with congestive heart failure of type heart and kidney Yang deficiency.


METHODS
90 patients of heart failure were randomly divided into 2 groups. 45 cases in the routine treatment group (RT) received general therapy including diuretics and digitalis, and 45 cases in the Chinese herb medicine group (CH) were treated basically with the above medicine, with additional manshuailing oral liquid. The clinical effect was summarized 6 weeks after treatment.


RESULTS
Total effect rate was 82.2% and 62.2% in CH and RTgroup respectively. Compared with pretreatment, heart function including stroke volume (SV), stroke volume index (SVI), cardiac index (CI), shorten rate of left ventricular short axe (deltaD%), distance of inter-ventricular septal to mitral valve (EPSS) were all improved significantly in both groups (P < 0.05 or P < 0.01), and with even better effects in the CH group than the RT group (P < 0.05 or P < 0.01), except the SV.


CONCLUSIONS
Manshuailing oral liquid can alleviate clinical symptom, decreased EPSS, increase deltaD% and improve heart function.
Yang
Ding-you
DY
The Institute of Geriatric Cardiology of PLA General Hospital, Beijing 100853 China.
Wu
Xing-li
XL
Xu
Hao
H
Duan
Xue-zhong
XZ
Wang
Shi-wen
SW
Lu
Zhi-zheng
ZZ
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D002316:Cardiotonic Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D004077:Digoxin / Q000627:therapeutic use; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000302:isolation & purification / Q000627:therapeutic use*; D005260:Female; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006334:Heart Function Tests; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use; D007548:Isosorbide Dinitrate / Q000627:therapeutic use; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D049993:Sodium Chloride Symporter Inhibitors / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000627:therapeutic use; D016711:Yang Deficiency / Q000188:drug therapy*
D002316:Cardiotonic Agents; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D049993:Sodium Chloride Symporter Inhibitors; D014665:Vasodilator Agents; D006852:Hydrochlorothiazide; D004077:Digoxin; D007548:Isosorbide Dinitrate