title: Treatment of locally recurrent rectal cancer with special focus on regional pelvic hyperthermia.
abstract: Progress in surgery and adjuvant therapy has markedly improved local control and survival rates in patients with primary, non-metastatic rectal cancer. However, the prognosis of patients with locally recurrent disease is still poor, and a realistic chance for repeated treatment with curative intent is still restricted to the minority of cases. Therefore, effective palliation of symptoms and preservation of a good quality of life are the major goals of therapy for most patients with local recurrence of rectal cancer. Here we give a short overview on the options available for the treatment of pelvic recurrence of rectal cancer, with special focus on adjunctive regional pelvic radiofrequency hyperthermia.
authors.affiliation: Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Campus Virchow-Klinikum, Charité Universitätsmedizin Berlin, Germany. bert.hildebrandt@charite.de
authors.forename: B
authors.initials: B
authors.lastname: Hildebrandt
authors.forename: P
authors.initials: P
authors.lastname: Wust
authors.forename: J
authors.initials: J
authors.lastname: Gellermann
authors.forename: A
authors.initials: A
authors.lastname: Nicolaou
authors.forename: R-U
authors.initials: RU
authors.lastname: Trappe
authors.forename: R
authors.initials: R
authors.lastname: Felix
authors.forename: H
authors.initials: H
authors.lastname: Riess
authors.forename: B
authors.initials: B
authors.lastname: Rau
mesh_terms: D003131:Combined Modality Therapy / Q000379:methods; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D010388:Pelvis; D012004:Rectal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D016896:Treatment Outcome