title: The ProDom database of protein domain families: more emphasis on 3D.
abstract: ProDom is a comprehensive database of protein domain families generated from the global comparison of all available protein sequences. Recent improvements include the use of three-dimensional (3D) information from the SCOP database; a completely redesigned web interface (http://www.toulouse.inra.fr/prodom.html); visualization of ProDom domains on 3D structures; coupling of ProDom analysis with the Geno3D homology modelling server; Bayesian inference of evolutionary scenarios for ProDom families. In addition, we have developed ProDom-SG, a ProDom-based server dedicated to the selection of candidate proteins for structural genomics.
authors.affiliation: Laboratoire des Interactions Plantes-Microorganismes, INRA/CNRS, BP 27, F-31326 Castanet-Tolosan Cedex, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Bru
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Courcelle
authors.forename: Sébastien
authors.initials: S
authors.lastname: Carrère
authors.forename: Yoann
authors.initials: Y
authors.lastname: Beausse
authors.forename: Sandrine
authors.initials: S
authors.lastname: Dalmar
authors.forename: Daniel
authors.initials: D
authors.lastname: Kahn
mesh_terms: D003196:Computer Graphics; D030562:Databases, Protein; D023281:Genomics; D020407:Internet; D008958:Models, Molecular; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry / Q000145:classification; D016415:Sequence Alignment; D020539:Sequence Analysis, Protein; D014584:User-Computer Interface
chemical_list: D011506:Proteins