[Effect of extract from shenghua decoction on myoelectric activity of rabbit uterine muscle in the latest period of pregnancy].
OBJECTIVE
To elucidate the difference between uterus body and cervix under the intervention of Shenghua decoction, and to observe the rabbit uterine muscle in the latest period of pregnancy for the way of myoelectric activity.


METHODS
PowerLab/8s was used to record myoelectric activity of rabbit muscle in uterus body and cervix which was in a general anaesthesia state induced by urethane.


RESULTS
Myoelectric activities of rabbit uterine smooth muscle in the latest period of pregnancy was enhanced in vivo by being treated with Shenghua decoction 40 mg x kg(-1) (P < 0.01) while cervix myoelectric activities had no significant change (P < 0.05).


CONCLUSIONS
Myoelectric activities of rabbit uterine muscle in the latest period of pregnancy are enhanced by being treated with Shenghua decoction so its hemostatic effect can be represented via the constriction of uterus body. Shenghua decoction is beneficial for child delivery because cervix myoelectric activities have no significant change under the intervention of Shenghua decoction while the myoelectric activities of uterus body are increased significantly.
Hong
Min
M
National Standard Lab of Pharmacology for Chinese Materia Medica, Nanjing 210029, Jiangsu, China. hongmin72@hotmail.com
Yu
Li
L
Ma
Cheng
C
Zhu
Quan
Q
D000200:Action Potentials / Q000187:drug effects; D029971:Angelica sinensis / Q000737:chemistry; D000818:Animals; D002584:Cervix Uteri / Q000187:drug effects / Q000502:physiology; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D029882:Glycyrrhiza uralensis / Q000737:chemistry; D030004:Ligusticum / Q000737:chemistry; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology*; D010946:Plants, Medicinal / Q000737:chemistry; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000502:physiology*; D011817:Rabbits; D014590:Uterine Contraction / Q000187:drug effects; D014599:Uterus / Q000187:drug effects / Q000502:physiology
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal