title: Hydroamination/Heck reaction sequence for a highly regioselective one-pot synthesis of indoles using 2-chloroaniline.
abstract: A one-pot indole synthesis consisting of a highly regioselective TiCl(4)-catalyzed hydroamination and a 5-endo Heck cyclization starting from 2-chloroaniline is described, using an in-situ generated, sterically hindered imidazol-2-ylidene palladium complex.
authors.affiliation: Department of Chemistry, Ludwig-Maximilians-Universität München, D-81377 München, Germany. lutz.ackermann@cup.uni-muenchen.de
authors.forename: Lutz
authors.initials: L
authors.lastname: Ackermann
authors.forename: Ludwig T
authors.initials: LT
authors.lastname: Kaspar
authors.forename: Christian J
authors.initials: CJ
authors.lastname: Gschrei