Corneal perforation with secondary congenital aphakia in Peters anomaly.
OBJECTIVE
To describe two cases of secondary congenital aphakia in association with Peters anomaly.


METHODS
Two infants were noted to have corneal opacification at birth. Each child was found to have Peters anomaly requiring corneal transplantation in 1 or both eyes.


RESULTS
Each child underwent penetrating keratoplasty, revealing absence of the crystalline lens in 1 eye. Histopathologic evaluation of the corneal buttons was performed. Each specimen showed full-thickness corneal defects with lens remnants.


CONCLUSIONS
Secondary congenital aphakia from corneal perforation should be considered in the presentation of severe Peters anomaly.
Banning
Chris S
CS
Emory Eye Center, Emory University, Atlanta, Georgia 30322, USA. cbanning@hotmail.com
Blackmon
Douglas M
DM
Song
C Diane
CD
Grossniklaus
Hans E
HE
D001035:Aphakia / Q000151:congenital* / Q000601:surgery; D003315:Cornea / Q000002:abnormalities*; D003318:Corneal Opacity / Q000151:congenital* / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D015948:Keratoplasty, Penetrating; D007908:Lens, Crystalline / Q000002:abnormalities*; D008297:Male; D012422:Rupture, Spontaneous