Is one Gy always one Gy? The integration between conventional radiotherapy and special techniques.
The new radiotherapy techniques as HDR and LDR brachytherapy, stereotactic radiotherapy, 3D-CRT, and IMRT require an accurate knowledge of the biological characteristics of the tumor with correct definition of target volumes. As demonstrated by the two reported cases, the formulae equivalent to 2 Gy in the special techniques are useful for the increase in the total dose to GTV while sparing the organs at risk.
Gabriele
Pietro
P
Unità di Radioterapia, Istituto per la Cura e la Ricerca sul Cancro, IRCC, Candiolo, Torino, Italy. pgabriele@mauriziano.it
Bona
Cristina
C
Piermattei
Angelo
A
Baiotto
Barbara
B
D000368:Aged; D001918:Brachytherapy; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D016889:Endometrial Neoplasms / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D008433:Mathematics; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D012062:Relative Biological Effectiveness