title: Susac syndrome: serial diffusion-weighted MR imaging.
abstract: Susac syndrome (SS) is a clinical triad of hearing loss, retinal artery occlusion and encephalopathy. The typical MR imaging findings of multiple focal lesions in the corpus callosum and subcortical white matter can be easily misdiagnosed as multiple sclerosis. On diffusion-weighted (DW) MR imaging, new lesions were hyperintense, with reduced apparent diffusion coefficient (ADC). These lesions later became less prominent or hypointense on subsequent DW MR imaging. Serial DW imaging and ADC maps may be useful in differentiating SS from demyelinating diseases.
authors.affiliation: Department of Neuroradiology, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore.
authors.forename: Mao Sheng
authors.initials: MS
authors.lastname: Xu
authors.forename: Chai Beng
authors.initials: CB
authors.lastname: Tan
authors.forename: T
authors.initials: T
authors.lastname: Umapathi
authors.forename: C C Tchoyoson
authors.initials: CC
authors.lastname: Lim
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001160:Arterioles / Q000000981:diagnostic imaging; D001927:Brain Diseases / Q000175:diagnosis* / Q000188:drug therapy; D003072:Cognition Disorders / Q000188:drug therapy / Q000209:etiology; D003337:Corpus Callosum / Q000473:pathology; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D006261:Headache / Q000209:etiology; D034381:Hearing Loss / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D011859:Radiography; D012074:Remission Induction; D012161:Retinal Artery / Q000000981:diagnostic imaging; D015356:Retinal Artery Occlusion / Q000175:diagnosis* / Q000188:drug therapy; D013577:Syndrome
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone