title: Monosomy 22 as a diagnostic aid in a case of late recurrence of adult granulosa cell tumor of the ovary.
abstract: Cytogenetic analysis of a case of metastatic granulosa cell tumor recurring 21 years after oophorectomy revealed monosomy 22. This anomaly, typical of granulosa cell tumor, coupled with the pathologic and immunophenotypic findings assisted in establishing the proper diagnosis of this lesion in the absence of the original histopathologic slides.
authors.affiliation: Department of Pathology, Creighton University Medical Center, 601 North 30th Street, Omaha, NE 68131, USA. caughron@creighton.edu
authors.forename: Samuel K
authors.initials: SK
authors.lastname: Caughron
authors.forename: Julia A
authors.initials: JA
authors.lastname: Bridge
authors.forename: Chhanda B
authors.initials: CB
authors.lastname: Bewtra
authors.forename: William J
authors.initials: WJ
authors.lastname: Hunter
authors.forename: Marilu
authors.initials: M
authors.lastname: Nelson
authors.forename: Suganthi
authors.initials: S
authors.lastname: Soundararajan
authors.forename: Edibaldo
authors.initials: E
authors.lastname: Silva
authors.forename: Zoran
authors.initials: Z
authors.lastname: Gatalica
mesh_terms: D000368:Aged; D002892:Chromosomes, Human, Pair 22; D005260:Female; D006106:Granulosa Cell Tumor / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007621:Karyotyping; D009006:Monosomy; D010051:Ovarian Neoplasms / Q000235:genetics*; D012186:Retroperitoneal Neoplasms / Q000235:genetics* / Q000473:pathology / Q000556:secondary*