Sebaceous carcinoma of the oral mucosa: case report and review of the literature.
Fordyce granules are found in the oral mucosa of up to 80% of adults. However, primary malignant sebaceous tumors of the oral mucosa are exceedingly rare. To our knowledge, only 5 examples of intraoral sebaceous carcinoma have been reported in the literature. This report describes a primary sebaceous carcinoma of the labial mucosa that arose in an area containing numerous Fordyce granules. A brief review of the clinical and histopathologic features of sebaceous carcinoma is also presented.
Alawi
Faizan
F
Department of Pathology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104-6002, USA. falawi@path.dental.upenn.edu
Siddiqui
Asma
A
D018266:Adenocarcinoma, Sebaceous / Q000473:pathology*; D000368:Aged; D001706:Biopsy; D002828:Choristoma / Q000473:pathology; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D008048:Lip Neoplasms / Q000473:pathology*; D008297:Male; D009059:Mouth Diseases / Q000473:pathology; D009061:Mouth Mucosa / Q000473:pathology; D018396:Mucin-1 / Q000032:analysis; D011944:Receptors, Androgen / Q000032:analysis; D012627:Sebaceous Glands / Q000473:pathology; D013545:Sweat Glands / Q000473:pathology
D018396:Mucin-1; D011944:Receptors, Androgen