title: Corneal melt after amniotic membrane transplant.
abstract: OBJECTIVE
  To report an eye-threatening complication associated with amniotic membrane grafting.
  
  
  METHODS
  Interventional case report.
  
  
  METHODS
  Retrospective review of the clinical and surgical records of a 43-year-old man who developed melting of his corneal graft after amniotic membrane transplantation.
  
  
  RESULTS
  Melting of a corneal graft after amniotic membrane transplantation was arrested by utilizing a tectonic, full-thickness corneal button denuded of endothelium in conjunction with a temporary tarsorraphy and systemic steroids.
  
  
  CONCLUSIONS
  To the best of our knowledge, this is the first report of an eye-threatening complication associated with amniotic membrane grafting. Caution should be exercised in utilizing amniotic membrane in patients who have undergone multiple ophthalmologic surgical procedures, which may sensitize the ocular immune system or lead to localized ischemia.
authors.affiliation: Rand Eye Institute, Pompano Beach, Florida 33064, USA. BDSCH77@AOL.COM
authors.forename: Barry A
authors.initials: BA
authors.lastname: Schechter
authors.forename: William J
authors.initials: WJ
authors.lastname: Rand
authors.forename: Robert S
authors.initials: RS
authors.lastname: Nagler
authors.forename: Irving
authors.initials: I
authors.lastname: Estrin
authors.forename: Stephen S
authors.initials: SS
authors.lastname: Arnold
authors.forename: Natalia
authors.initials: N
authors.lastname: Villate
authors.forename: Gabriel E
authors.initials: GE
authors.lastname: Velazquez
mesh_terms: D000328:Adult; D000650:Amnion / Q000637:transplantation*; D001684:Biological Dressings / Q000009:adverse effects*; D003316:Corneal Diseases / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D016039:Corneal Transplantation; D019573:Epithelium, Corneal / Q000502:physiology; D005143:Eyelids / Q000601:surgery; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D012189:Retrospective Studies
chemical_list: D005938:Glucocorticoids