title: A case of epidermal cyst with pilomatrical differentiation.
abstract: A 20-year-old Japanese woman with an epidermal cyst on the back is described. Physical examination revealed a deep blue and round shaped cystic lesion measuring 10 min in diameter. A comedo-like keratotic plug also could be seen at the center. Histologically, the inner surface of the cyst was clearly separated of two types of the cells. The one was layers of epidermal keratinocytes and the other looked like a basal layer of epidermis, which immunohistochemically stained by S-100, HMB-45, cytokeratin (CK19) and Fontana-Masson staining. We diagnosed this case as epidermal cyst with pilomatrical differentiation.
authors.affiliation: Department of Dermatology, Tokai University School of Medicine, Kanagawa, Japan.
authors.forename: Norihiro
authors.initials: N
authors.lastname: Ikoma
authors.forename: Kenichi
authors.initials: K
authors.lastname: Iwashita
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Umezawa
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsuyama
authors.forename: Yukinori
authors.initials: Y
authors.lastname: Ohta
authors.forename: Akira
authors.initials: A
authors.lastname: Ozawa
authors.forename: Shinobu
authors.initials: S
authors.lastname: Umemura
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Ueyama
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Yamazaki
mesh_terms: D000328:Adult; D002454:Cell Differentiation; D004814:Epidermal Cyst / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D004817:Epidermis / Q000378:metabolism / Q000473:pathology; D005260:Female; D018859:Hair Follicle / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D015603:Keratinocytes / Q000166:cytology; D007633:Keratins / Q000378:metabolism; D009418:S100 Proteins / Q000378:metabolism; D012835:Silver Nitrate; D012871:Skin Diseases / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D013194:Staining and Labeling; D016896:Treatment Outcome
chemical_list: C051037:Fontana-Masson stain; D009418:S100 Proteins; D007633:Keratins; D012835:Silver Nitrate