title: Gold and silver nanoparticles functionalized with known numbers of oligonucleotides per particle for DNA detection.
abstract: The biospecificity of gold and silver nanoparticles, functionalized with known numbers of oligonucleotides, is demonstrated in colorimetric microbead assays for complementary and mismatch sequences.
authors.affiliation: Department of Chemistry and Centre for Bioarray Innovation, Liverpool University, Liverpool, UK L69 7ZD.
authors.forename: Yang
authors.initials: Y
authors.lastname: Chen
authors.forename: Jenny
authors.initials: J
authors.lastname: Aveyard
authors.forename: Robert
authors.initials: R
authors.lastname: Wilson
mesh_terms: D001483:Base Sequence; D003124:Colorimetry / Q000379:methods*; D004247:DNA / Q000032:analysis* / Q000235:genetics*; D006046:Gold / Q000737:chemistry*; D008863:Microspheres; D049329:Nanostructures / Q000737:chemistry*; D009841:Oligonucleotides / Q000737:chemistry* / Q000235:genetics; D012834:Silver / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: D009841:Oligonucleotides; D012834:Silver; D006046:Gold; D004247:DNA