title: Low frequency of BMPR2 mutations in a German cohort of patients with sporadic idiopathic pulmonary arterial hypertension.
authors.affiliation: Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Koehler
authors.forename: E
authors.initials: E
authors.lastname: Grünig
authors.forename: M W
authors.initials: MW
authors.lastname: Pauciulo
authors.forename: M M
authors.initials: MM
authors.lastname: Hoeper
authors.forename: H
authors.initials: H
authors.lastname: Olschewski
authors.forename: H
authors.initials: H
authors.lastname: Wilkens
authors.forename: M
authors.initials: M
authors.lastname: Halank
authors.forename: J
authors.initials: J
authors.lastname: Winkler
authors.forename: R
authors.initials: R
authors.lastname: Ewert
authors.forename: H
authors.initials: H
authors.lastname: Bremer
authors.forename: S
authors.initials: S
authors.lastname: Kreuscher
authors.forename: B
authors.initials: B
authors.lastname: Janssen
authors.forename: W C
authors.initials: WC
authors.lastname: Nichols
mesh_terms: D000328:Adult; D000595:Amino Acid Sequence; D000818:Animals; D052006:Bone Morphogenetic Protein Receptors, Type II; D015331:Cohort Studies; D004252:DNA Mutational Analysis; D005787:Gene Frequency; D005858:Germany; D006801:Humans; D006976:Hypertension, Pulmonary / Q000235:genetics*; D008969:Molecular Sequence Data; D009154:Mutation; D017346:Protein Serine-Threonine Kinases / Q000235:genetics*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D016415:Sequence Alignment
chemical_list: D017346:Protein Serine-Threonine Kinases; C498218:BMPR2 protein, human; D052006:Bone Morphogenetic Protein Receptors, Type II