title: Uterine contractions evaluated on cine MR imaging in patients with uterine leiomyomas.
abstract: OBJECTIVE
  Submucosal leiomyoma is one of the most recognized causes of infertility and habitual abortion. The purpose of this study is to evaluate uterine peristalsis, a cycle-related inherent contractility of uterus probably responsible for sperm transport and conservation of pregnancy, in patients with uterine leiomyomas using cine magnetic resonance (MR) imaging.
  
  
  METHODS
  Study population consisted of 26 female patients (age range: 19-51 years, mean: 41 years), in which 16 patients had submucosal leiomyomas and 10 patients had intramural or subserosal leiomyomas. We prospectively performed MR imaging of the midsagittal plane of uterus using 1.5 T magnet (Symphony, Siemens Medical Systems) with a body array coil, and obtained 60 half-Fourier acquisition single shot turbo spin echo (HASTE) images (Echo time=80 ms, FOV=300 mm, slice thickness 5 mm, matrix 256x256) within 2 min, and displayed them on cine mode at 12x faster than real speed. Evaluated were peristaltic movements at the endometral-myometrial junction and focal myometrial movements, adjacent to leiomyomas, regarding presence, direction, frequency, and conduction.
  
  
  RESULTS
  The peristaltic movements were identified in 12/16 patients with submucosal lesions and 10/10 with other leiomyomas. The frequency and direction were cycle-related. Loss of peristalsis was noted adjacent to submucosal myomas in 4/12 patients, but was not in others. Focal myometrial movements were noted in 9/16 patients with submucosal myomas, but not in others.
  
  
  CONCLUSIONS
  Uterine peristaltic movements were partly interrupted by submucosal leiomoymas, but not by myometrial or subserosal leiomyomas. Loss of peristalsis and focal myometrial movements was noted only adjacent to submucosal leiomyomas. These findings are considered to represent dysfunctional contractility, and may be related with pregnancy loss.
authors.affiliation: Department of Radiology, Kyoto City Hospital, Kyoto, Japan. mizuki@mbox.kyoto-inet.or.jp
authors.forename: Mizuki
authors.initials: M
authors.lastname: Nishino
authors.forename: Kaori
authors.initials: K
authors.lastname: Togashi
authors.forename: Asako
authors.initials: A
authors.lastname: Nakai
authors.forename: Katsumi
authors.initials: K
authors.lastname: Hayakawa
authors.forename: Shotarou
authors.initials: S
authors.lastname: Kanao
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Iwasaku
authors.forename: Shingo
authors.initials: S
authors.lastname: Fujii
mesh_terms: D000328:Adult; D004717:Endometrium / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007889:Leiomyoma / Q000473:pathology / Q000503:physiopathology*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods; D008875:Middle Aged; D009092:Mucous Membrane / Q000473:pathology; D009215:Myometrium / Q000473:pathology / Q000503:physiopathology; D011446:Prospective Studies; D012704:Serous Membrane / Q000473:pathology; D014590:Uterine Contraction / Q000502:physiology*; D014594:Uterine Neoplasms / Q000473:pathology / Q000503:physiopathology*