[Systolic and diastolic function of heart ventricles and their remodeling in adult patients with congenital heart disease in phase of Eisenmenger's syndrome].
55 patients with congenital heart diseases (CHD) in phase of Eisenmereger's syndrome (ES) (11 patients with ductus arteriosus (DA), 28--ventricular septal defect (VSD), 16--atrial septal defect (ASD)) at age of 14-53 (mean 29.7+/-3.2) were examined. Heart failure corresponded to I-II functional classes (NYHA) in 28 (50.9%) patients, III-IV--in 27 (49.1%). Diagnosis of ES was confirmed by ECG, Doppler-Echo-CG, catheterization and ventriculography. Moderate right ventricle systolic dysfunction was revealed and confirmed by its dilation and deterioration of inferior vena cava (IVC) (for 156.0% in comparision with healthy people, P<0.001) in patients DA and ASD collapse after inspiration. Unchanged indices of Vmax and Accmax in PA and IVC diameter showed good compensatory potential of RV. There was the initial stage of LV systolic dysfunction (decrease EF for 7.0%, Vmax for 16.7% and Accmax for 21.4%, P<0.05). Diastolic dysfunction of both ventricles in patients with ES is unidirectional and corresponds to relaxation type.
Amosova
K M
KM
Konopl'ova
L F
LF
Tashova
S P
SP
Kazakov
V Ie
VIe
Rudenko
Iu V
IuV
D000293:Adolescent; D000328:Adult; D003971:Diastole / Q000502:physiology; D004541:Eisenmenger Complex / Q000503:physiopathology; D005260:Female; D006330:Heart Defects, Congenital / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013599:Systole / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*; D020257:Ventricular Remodeling / Q000502:physiology*