title: Calculation of the peak concentration of 2-chlorobenzamide generated in the hydrolysis of the benzoylphenylurea insecticide 1-(2-chlorobenzoyl)-3-(4-chlorophenyl)urea.
abstract: 1-(2-chlorobenzoyl)-3-(4-chlorophenyl)urea (CCU), a new analogue of diflubenuron and PH-6038, has been widely used in agriculture and forestry as a molt-inhibiting hormone insecticide which was developed in China. 2-Chlorobenzamide, a main degradation product of CCU in the environment, has been identified as a potential carcinogen, so the content of 2-chlorobenzamide from the breakup of CCU will directly affect the environmental safety of CCU. In this paper we describe a simple, rapid, and convenient prediction model for predicting the level and time of occurrence of the peak concentration of 2-chlorobenzamide in the hydrolysis of CCU verified by experimental data. The time for reaching the peak concentration of 2-chlorobenzamide (tm) at 25 degrees C and pH 6 is 13.5 d, and the maximum concentration of 2-chlorobenzamide (ym) is 3.2% of the initial concentration of CCU according to the results from the prediction model. These results are similar to the real values from the experiments, which are 22 d and 1.6% of the initial concentration of CCU, respectively. The difference between the values of the prediction and experiment is discussed, and it is demonstrated that the predicting model is highly credible.
authors.affiliation: Henan Key Laboratory for Environmental Pollution Control and School of Chemistry and Environmental Sciences, Henan Normal University, Xinxiang 453007, Henan, People's Republic of China.
authors.forename: Wenying
authors.initials: W
authors.lastname: Lu
authors.forename: Qingxiang
authors.initials: Q
authors.lastname: Zhou
authors.forename: Guoguang
authors.initials: G
authors.lastname: Liu
mesh_terms: D001549:Benzamides / Q000032:analysis*; D002273:Carcinogens / Q000032:analysis; D004785:Environmental Pollutants / Q000032:analysis; D006207:Half-Life; D006868:Hydrolysis; D007306:Insecticides / Q000737:chemistry*; D013997:Time Factors; D014508:Urea / Q000031:analogs & derivatives* / Q000737:chemistry*
chemical_list: C495513:1-(2-chlorobenzoyl)-3-(4-chlorophenyl)urea; D001549:Benzamides; D002273:Carcinogens; D004785:Environmental Pollutants; D007306:Insecticides; D014508:Urea; C412475:2-chlorobenzamide