title: Anti-fungal sesquiterpenoid from the root exudate of Solanum abutiloides.
abstract: The Solanum abutiloides plant is highly resistant to soil-borne pathogens such as Fusarium oxysporum f. sp. melongenae, Verticillium dahliae, and Ralstonia solanacearum. This species is utilized as a mating source of resistant cultivars and is also used as a rootstock. The root exudate of Solanum abutiloides was extracted from a soil system composed of charcoal and vermiculite. Anti-fungal activity was found in the extract, and an active ingredient was isolated. The chemical structure of the active compound was determined to be 3-beta-acetoxysolavetivone, a new sesquiterpenoid. The anti-fungal activity of 3-beta-acetoxysolavetivone examined by the inhibition of spore germination of Fusarium oxysporum was close to that of lubimin, and higher than that of solavetivone.
authors.affiliation: Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University, Sapporo 060-8589, Japan.
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Yokose
authors.forename: Kozue
authors.initials: K
authors.lastname: Katamoto
authors.forename: Sun
authors.initials: S
authors.lastname: Park
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Matsuura
authors.forename: Teruhiko
authors.initials: T
authors.lastname: Yoshihara
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005670:Fusarium / Q000187:drug effects; D015394:Molecular Structure; D010936:Plant Extracts; D018517:Plant Roots / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D012987:Soil; D032322:Solanum / Q000737:chemistry*; D013172:Spores, Fungal / Q000187:drug effects; D013141:Spiro Compounds; D000094162:Phytoalexins
chemical_list: D000935:Antifungal Agents; D005663:Furans; D010936:Plant Extracts; D012717:Sesquiterpenes; D012987:Soil; C438421:solavetivone; D013141:Spiro Compounds; D000094162:Phytoalexins