Nitrous oxide (laughing gas) facilitates excitability in rat hippocampal slices through gamma-aminobutyric acid A receptor-mediated disinhibition.
Nagashima
Kimimoto
K
Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Zorumski
Charles F
CF
Izumi
Yukitoshi
Y
D018685:Anesthetics, Inhalation / Q000494:pharmacology*; D000818:Animals; D004558:Electric Stimulation; D018691:Excitatory Amino Acid Antagonists / Q000494:pharmacology; D019706:Excitatory Postsynaptic Potentials / Q000187:drug effects*; D005110:Extracellular Space / Q000502:physiology; D018756:GABA Antagonists / Q000494:pharmacology; D058785:GABA-A Receptor Agonists; D058787:GABA-A Receptor Antagonists; D006624:Hippocampus / Q000187:drug effects*; D066298:In Vitro Techniques; D007649:Ketamine / Q000494:pharmacology; D008297:Male; D009609:Nitrous Oxide / Q000494:pharmacology*; D010852:Picrotoxin / Q000494:pharmacology; D017966:Pyramidal Cells / Q000187:drug effects; D051381:Rats; D017207:Rats, Sprague-Dawley; D011963:Receptors, GABA-A / Q000187:drug effects*; D016194:Receptors, N-Methyl-D-Aspartate / Q000187:drug effects; D009435:Synaptic Transmission / Q000187:drug effects
D018685:Anesthetics, Inhalation; D018691:Excitatory Amino Acid Antagonists; D018756:GABA Antagonists; D058785:GABA-A Receptor Agonists; D058787:GABA-A Receptor Antagonists; D007649:Ketamine; D009609:Nitrous Oxide; D010852:Picrotoxin; D011963:Receptors, GABA-A; D016194:Receptors, N-Methyl-D-Aspartate