Corneal melt after amniotic membrane transplant.
OBJECTIVE
To report an eye-threatening complication associated with amniotic membrane grafting.


METHODS
Interventional case report.


METHODS
Retrospective review of the clinical and surgical records of a 43-year-old man who developed melting of his corneal graft after amniotic membrane transplantation.


RESULTS
Melting of a corneal graft after amniotic membrane transplantation was arrested by utilizing a tectonic, full-thickness corneal button denuded of endothelium in conjunction with a temporary tarsorraphy and systemic steroids.


CONCLUSIONS
To the best of our knowledge, this is the first report of an eye-threatening complication associated with amniotic membrane grafting. Caution should be exercised in utilizing amniotic membrane in patients who have undergone multiple ophthalmologic surgical procedures, which may sensitize the ocular immune system or lead to localized ischemia.
Schechter
Barry A
BA
Rand Eye Institute, Pompano Beach, Florida 33064, USA. BDSCH77@AOL.COM
Rand
William J
WJ
Nagler
Robert S
RS
Estrin
Irving
I
Arnold
Stephen S
SS
Villate
Natalia
N
Velazquez
Gabriel E
GE
D000328:Adult; D000650:Amnion / Q000637:transplantation*; D001684:Biological Dressings / Q000009:adverse effects*; D003316:Corneal Diseases / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D016039:Corneal Transplantation; D019573:Epithelium, Corneal / Q000502:physiology; D005143:Eyelids / Q000601:surgery; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D012189:Retrospective Studies
D005938:Glucocorticoids