[An experimental study of cellular mechanic properties of intestinal epithelial cells by micropipette aspiration].
OBJECTIVE
To further understand the mechanic properties of the Intestinal Epithelial cells (IEC).


METHODS
The viscoelastic properties of the IEC-6 were determined by micropipette aspiration.


RESULTS
The elastic coefficient K1 was 436.21 +/- 89.64 dyn/cm2 and K2 was 298.37 +/- 75.16 dyn/cm2. The visous coefficient micro was 15.94 +/- 4.93 dyn/(sec x cm2).


CONCLUSIONS
The elastic component reflects the degree of initial deformation of the IEC and makes a notable impact on the deformation of the IEC. The viscous component reflects the time dependency of the deformation of the IEC and influences the velocity of the IEC deformation.
Chen
Jun
J
Department of Pharmaceutical Analysis, West China School of Pharmacy, Sichuan Unviersity, Chengdu 610041, China.
Xiao
Guangxia
G
Wu
Zezhi
Z
Qin
Jian
J
Li
Zhangwan
Z
D001696:Biomechanical Phenomena; D002448:Cell Adhesion / Q000502:physiology; D002453:Cell Cycle / Q000502:physiology; D003599:Cytoskeleton; D004548:Elasticity; D042783:Endothelial Cells / Q000166:cytology / Q000502:physiology*; D006801:Humans; D007422:Intestines / Q000166:cytology*; D012212:Rheology; D013314:Stress, Mechanical; D014783:Viscosity