title: Prevalence of rubella antibody in pregnant women in Ibadan, Nigeria.
abstract: BACKGROUND
  There is a dearth of information on the incidence and prevalence of rubella infection in Nigeria. The risk of congenital rubella in sero-negative pregnant women has been found to produce congenital abnormalities even in developed countries.
  
  
  OBJECTIVE
  The aim of this study is to determine the prevalence of rubella virus antibody in pregnant women.
  
  
  METHODS
  The place of study is the antenatal care clinic of Adeoyo State Hospital, Ibadan.
  
  
  METHODS
  This is a cross-sectional study of primigravida women attending the antenatal care facilities in a general hospital The rubella IgG antibody of the women was detected in sera using the RUB IgG Test kit. This is a quantitative ELISA technique.
  
  
  RESULTS
  The prevalence of rubella antibody in 159 pregnant women that participated in this study was 68.5% with a confidence interval of 64.8% - 72.2%. Women living in rural -urban areas have statistically significant higher prevalence of antibody than those in urban areas.
  
  
  CONCLUSIONS
  This prevalence of rubella antibody in pregnant women suggests 1 in 4 pregnant woman is susceptible and the foetus at risk of congenital rubella malformation.
authors.affiliation: Institute of Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan.
authors.forename: A E
authors.initials: AE
authors.lastname: Bamgboye
authors.forename: K A
authors.initials: KA
authors.lastname: Afolabi
authors.forename: F I
authors.initials: FI
authors.lastname: Esumeh
authors.forename: I B
authors.initials: IB
authors.lastname: Enweani
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008403:Mass Screening; D009549:Nigeria / Q000453:epidemiology; D010044:Outpatient Clinics, Hospital; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood / Q000453:epidemiology / Q000276:immunology*; D012409:Rubella / Q000097:blood / Q000453:epidemiology / Q000276:immunology*; D012412:Rubella virus / Q000276:immunology*; D012423:Rural Health; D016036:Seroepidemiologic Studies; D014504:Urban Health
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; C040901:rubella antibodies