Malignant peripheral nerve sheath tumor of the paranasal sinuses.
Malignant peripheral nerve sheath tumors of the nose and paranasal sinuses are extremely uncommon. We report the case of a 65-year-old woman who presented with a rapid emergence of "nasal polyps" that completely obstructed her nasal passages. Six years earlier she had been assessed elsewhere for nasal polyps. At presentation, the patient exhibited gross polyposis, with lesions protruding from both nostrils. Histology confirmed a diagnosis of a malignant peripheral nerve sheath tumor This case demonstrates that symptoms of nasal obstruction are not always secondary to simple causes. We discuss the clinical picture of nasal and paranasal malignant peripheral nerve sheath tumor, its pathology, and its treatment.
Ahsan
Farhan
F
Department of Otolaryngology-Head and Neck Surgery, Aberdeen Royal Infirmary, University of Aberdeen, Foresterhill, Aberdeen, Scotland.
Lee
Maggie K
MK
Ah-See
Kim W
KW
Chapman
Andrea D
AD
D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D003110:Colonic Neoplasms / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D015508:Nasal Obstruction / Q000209:etiology; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D016609:Neoplasms, Second Primary / Q000175:diagnosis; D018317:Nerve Sheath Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010255:Paranasal Sinus Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery