title: [New composite implant for tracheal reconstruction--preliminary study].
abstract: Stenosis of trachea's diameter occurs the most often as complications after intubation and tracheotomy. Among the other reasons of narrowing of this organ the following are being named: mechanical injuries, chemical damages, primary and metastasis tumors. The therapy of trachea's stenosis includes both alternative and radical treatments. The radical treatment consists of surgical excision of the narrowed segment followed by reconstruction of trachea (anastomosing of free ends or filling of lost segment with use of auto- or allogenic material). There is no appropriate alloplastic material developed to date, the use of which in reconstructive surgery of large segment trachea defects would bring about positive long-term experimental results. The success of alloplastic material implantation in the reconstruction of large tracheal defects is limited by the fact that the biomechanical characteristics of replaced tissue are distinctly different from synthetic material. The work is devoted to evaluation of complex mechanical characteristic of natural sheep trachea before designing the proper synthetic material for large tracheal defects reconstruction. Various mechanical tests were conducted to study the mechanical behavior of total trachea. Samples of tissue cut out from trachea were also examined. The results revealed strong directional--dependent mechanical properties of trachea. Composite constituents, namely carbon fibers and biocompatible and biostable polysulfone were used to manufacture the implant.
authors.affiliation: Katedra i Oddział Kliniczny Laryngologii Sl. AM w Zabrzu.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Scierski
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Namysłowski
authors.forename: Stanisław
authors.initials: S
authors.lastname: Błazewicz
authors.forename: Jan
authors.initials: J
authors.lastname: Pilch
authors.forename: Marta
authors.initials: M
authors.lastname: Błazewicz
authors.forename: Bozena
authors.initials: B
authors.lastname: Konieczna
mesh_terms: D000818:Animals; D003188:Composite Resins; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods*; D019736:Prostheses and Implants; D019651:Plastic Surgery Procedures / Q000379:methods*; D012756:Sheep; D014135:Tracheal Stenosis / Q000601:surgery*
chemical_list: D003188:Composite Resins