title: Dichloromethane as an unusual methylene equivalent. A new entry of highly nucleophilic and selective titanium-methylene complexes for ester methylenation.
abstract: [reaction: see text] The successful application of CH2Cl2-Mg-TiCl4-system mediated methylenation of various esters such as tert-butyl ester and 2,5-cyclohexadiene-1-carboxylate highlights the extraordinary reactivity, selectivity, and the nonbasic nature of this new methylene-carbenoid, which serves as a practical reagent applicable to large-scale synthesis.
authors.affiliation: Department of Chemistry, National Chung-Hsing University, Taichung 400, Taiwan, Republic of China. thyan@mail.nchu.edu.tw
authors.forename: Tu-Hsin
authors.initials: TH
authors.lastname: Yan
authors.forename: Ching-Ting
authors.initials: CT
authors.lastname: Chien
authors.forename: Chia-Chung
authors.initials: CC
authors.lastname: Tsai
authors.forename: Kuo-Wei
authors.initials: KW
authors.lastname: Lin
authors.forename: Yen-Hsien
authors.initials: YH
authors.lastname: Wu