title: Phage display vectors for the in vitro generation of human antibody fragments.
abstract: A major source of human antibodies are phage display libraries, which are constructed from various genetic sources. Antibodies are expressed as scFV and Fab antibody fragments using various vector systems. This review offers a comprehensive overview of M13 phage display antibody vectors and discusses their applications.
authors.affiliation: Department of Biotechnology, Institute of Biochemistry and Biotechnology, Carolo-Wilhelmina Technical University, Braunschweig, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Hust
authors.forename: Stefan
authors.initials: S
authors.lastname: Dübel
mesh_terms: D000911:Antibodies, Monoclonal / Q000235:genetics*; D017104:Bacteriophage M13 / Q000235:genetics; D003001:Cloning, Molecular / Q000379:methods*; D005822:Genetic Vectors / Q000235:genetics*; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000235:genetics*; D007135:Immunoglobulin Variable Region / Q000235:genetics*
chemical_list: D000911:Antibodies, Monoclonal; D007147:Immunoglobulin Light Chains; D007135:Immunoglobulin Variable Region