title: Cystatin C as a marker of GFR--history, indications, and future research.
abstract: OBJECTIVE
  To summarize recent knowledge on the small molecular weight protein cystatin C (cys-C) and its use as a marker of the glomerular filtration rate (GFR).
  
  
  METHODS
  A multinational expert meeting was held in April 2002 in Marburg, Germany. Contributors summarized their main findings.
  
  
  CONCLUSIONS
  Cys-C is at least equal if not superior to serum creatinine as a marker of GFR. The independence from height, gender, age, and muscle mass is advantageous. Select patient groups such as children, the elderly, and patients with reduced muscle mass benefit in particular.
authors.affiliation: Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Canada. filler@cheo.on.ca
authors.forename: Guido
authors.initials: G
authors.lastname: Filler
authors.forename: Arend
authors.initials: A
authors.lastname: Bökenkamp
authors.forename: W
authors.initials: W
authors.lastname: Hofmann
authors.forename: Thierry
authors.initials: T
authors.lastname: Le Bricon
authors.forename: Cecília
authors.initials: C
authors.lastname: Martínez-Brú
authors.forename: Anders
authors.initials: A
authors.lastname: Grubb
mesh_terms: D000293:Adolescent; D000368:Aged; D015415:Biomarkers; D002648:Child; D055316:Cystatin C; D015891:Cystatins; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D016030:Kidney Transplantation; D011247:Pregnancy
chemical_list: D015415:Biomarkers; C525030:CST3 protein, human; D055316:Cystatin C; D015891:Cystatins