Dissociation of action and object naming: evidence from cortical stimulation mapping.
This cortical stimulation mapping study investigates the neural representation of action and object naming. Data from 13 neurosurgical subjects undergoing awake cortical mapping is presented. Our findings indicate clear evidence of differential disruption of noun and verb naming in the context of this naming task. At the individual level, evidence was found for punctuate regions of perisylvian cortex subserving noun and verb function. Across subjects, however, the location of these sites varied. This finding may help explain discrepancies between lesion and functional imaging studies of noun and verb naming. In addition, an alternative coding of these data served to highlight the grammatical class vulnerability of the target response. The use of this coding scheme implicates a role for the supramarginal gyrus in verb-naming behavior. These data are discussed with respect to a functional-anatomical pathway underlying verb naming.
Corina
David P
DP
Department of Psychology, University of Washington, Seattle, Washington 98195, USA. corina@u.washington.edu
Gibson
Erin K
EK
Martin
Richard
R
Poliakov
Andrew
A
Brinkley
James
J
Ojemann
George A
GA
D000328:Adult; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000033:anatomy & histology* / Q000502:physiology*; D004558:Electric Stimulation; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007802:Language; D007807:Language Tests; D008297:Male; D008959:Models, Neurological; D009434:Neural Pathways / Q000033:anatomy & histology* / Q000502:physiology*; D015588:Observer Variation; D010296:Parietal Lobe / Q000502:physiology; D013060:Speech / Q000502:physiology*; D013702:Temporal Lobe / Q000033:anatomy & histology / Q000502:physiology; D014705:Verbal Behavior / Q000502:physiology*