EPR tooth dosimetry as a tool for validation of retrospective doses: an end-user perspective.
The US Department of Energy (DOE) is co-funding several studies on health effects of radiation in Southern Urals in Russia and on Chernobyl liquidators in Ukraine. Obtaining dose-response relationships is central to all these studies. In order to validate retrospective doses estimated by various methods, Electron paramagnetic Resonance (EPR) tooth dosimetry, considered by many as a gold standard, was attempted. The EPR technique, however, has some limitations. This paper discusses the potential pitfalls of using EPR tooth dosimetry, and some potential solutions.
Bhat
Mohandas
M
Office of Health Studies, EH-51, 270 Corporate Center, Department of Energy, 1000 Independence Ave. SW Washington, DC 20585, USA. mohandas.bhat@eh.doe.gov
D016477:Artifacts; D001417:Background Radiation; D019985:Benchmarking / Q000379:methods; D001822:Body Burden; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods* / Q000592:standards*; D006801:Humans; D066298:In Vitro Techniques; D038622:Internationality; D008963:Molar / Q000737:chemistry* / Q000528:radiation effects*; D011829:Radiation Dosage; D011874:Radiometry / Q000379:methods* / Q000592:standards*; D012015:Reference Standards; D012062:Relative Biological Effectiveness; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity