Oral controlled release dosage forms. II. Glassy polymers in hydrophilic matrices.
Part I of this article reported general considerations of oral controlled release dosage forms and the applications of cellulose ether polymers in hydrophilic matrices. Part II of this study describes the advantages and disadvantages of limited swelling hydrophilic matrices, their preparation, mechanism, and parameters affecting drug release from these systems.
Veiga
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Laboratory of Galenic and Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra, P-3049, Coimbra, Portugal.
Salsa
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Pina
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D000284:Administration, Oral; D003432:Cross-Linking Reagents / Q000737:chemistry; D003692:Delayed-Action Preparations; D016503:Drug Delivery Systems / Q000379:methods*; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*
D003432:Cross-Linking Reagents; D003692:Delayed-Action Preparations; D004364:Pharmaceutical Preparations; D011108:Polymers