title: Subfulminant liver failure associated with quetiapine.
abstract: We report the clinical history of a patient with drug induced liver injury due to quetiapine who ultimately developed subfulminant hepatic failure and died. The clinical presentation, laboratory data, as well as liver histopathology were supportive of the putative diagnosis of drug induced liver injury. To our knowledge, this is the first report of the important association between quetiapine and drug induced liver injury.
authors.affiliation: Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
authors.forename: Ihab
authors.initials: I
authors.lastname: El Hajj
authors.forename: Ala I
authors.initials: AI
authors.lastname: Sharara
authors.forename: Don C
authors.initials: DC
authors.lastname: Rockey
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000188:drug therapy; D003987:Dibenzothiazepines / Q000009:adverse effects*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D017093:Liver Failure / Q000139:chemically induced* / Q000473:pathology; D008875:Middle Aged; D000069348:Quetiapine Fumarate
chemical_list: D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate