title: Transcription factors, pancreatic development, and beta-cell maintenance.
abstract: Transcription factors play an important role during pancreatic development ensuring normal differentiation of the islet endocrine cells. In mature beta-cells, expression of specific transcription factors is essential in maintaining normal beta-cell function.
authors.affiliation: Diabetes Research Group, Medical Research Council, Tygerberg, South Africa. marlon.cerf@mrc.ac.za
authors.forename: M E
authors.initials: ME
authors.lastname: Cerf
authors.forename: C J F
authors.initials: CJ
authors.lastname: Muller
authors.forename: D F
authors.initials: DF
authors.lastname: Du Toit
authors.forename: J
authors.initials: J
authors.lastname: Louw
authors.forename: S A
authors.initials: SA
authors.lastname: Wolfe-Coote
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism* / Q000473:pathology; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D007515:Islets of Langerhans / Q000254:growth & development* / Q000378:metabolism* / Q000473:pathology; D010179:Pancreas / Q000196:embryology / Q000254:growth & development* / Q000378:metabolism* / Q000473:pathology; D014157:Transcription Factors / Q000378:metabolism*
chemical_list: D014157:Transcription Factors