Rat immunoglobulins.
Five immunoglobulin isotypes (or classes) have been identified in the human as well as in the rat species. The homologies between the human and the rat immunoglobulin classes have been well defined with the help of the monoclonal immunoglobulins produced by the LOU immunocytomas (plasmocytomas,myeloma tumours). The LOU rat immunocytomas model, the physicochemical and the biological properties of the rat immunoglobulins are described in this review.
Rousseaux
J
J
Institut de Recherche sur le Cancer, INSERM U124, Place de Verdun, B.P. 3567, 59020 Lille, France.
Bazin
H
H
D000818:Animals; D000911:Antibodies, Monoclonal / Q000737:chemistry / Q000276:immunology* / Q000302:isolation & purification; D007126:Immunoglobulin Allotypes / Q000737:chemistry / Q000276:immunology; D007132:Immunoglobulin Isotypes / Q000737:chemistry / Q000276:immunology* / Q000302:isolation & purification; D009194:Myeloma Proteins / Q000276:immunology; D051381:Rats; D011919:Rats, Inbred Strains / Q000276:immunology*
D000911:Antibodies, Monoclonal; D007126:Immunoglobulin Allotypes; D007132:Immunoglobulin Isotypes; D009194:Myeloma Proteins