title: Direct intramolecular arylation of unactivated arenes: application to the synthesis of aporphine alkaloids.
abstract: The direct intramolecular C-H arylation of unactivated arenes is a viable strategy for the synthesis of aporphine alkaloids. These reactions occur with 3 to 5 mol% catalyst and generate the aporphine skeleton in up to 99% yield.
authors.affiliation: Center for Catalysis Research and Innovation, University of Ottawa, Department of Chemistry, 10 Marie Curie, Ottawa, Canada K1N 6N5.
authors.forename: Marc
authors.initials: M
authors.lastname: Lafrance
authors.forename: Nicole
authors.initials: N
authors.lastname: Blaquière
authors.forename: Keith
authors.initials: K
authors.lastname: Fagnou
mesh_terms: D001060:Aporphines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012997:Solvents; D013696:Temperature
chemical_list: D001060:Aporphines; D012997:Solvents