Absence of de novo Y-chromosome microdeletions in male children conceived through intracytoplasmic sperm injection.
Molecular screening for Y-chromosome microdeletions in 96 Spanish male children conceived through intracytoplasmic sperm injection (ICSI) was conducted. No microdeletions were detected; these results support the notion that de novo Y-chromosome alterations are rare and unrelated to the ICSI technique itself.
Buch
Belén
B
Unidad de Reproducción, Centro Gutenberg, Málaga, Spain.
Galán
José Jorge
JJ
Lara
Miguel
M
Real
Luis Miguel
LM
Martínez-Moya
Manuel
M
Ruiz
Agustín
A
D000328:Adult; D002648:Child; D002872:Chromosome Deletion; D041322:Chromosomes, Human, Y / Q000235:genetics*; D003199:Computer Systems; D003456:Cryptorchidism / Q000235:genetics; D005220:Fathers; D005306:Fertilization; D005787:Gene Frequency; D005820:Genetic Testing; D006801:Humans; D008297:Male; D009030:Mosaicism; D009845:Oligospermia / Q000235:genetics / Q000503:physiopathology; D016133:Polymerase Chain Reaction; D012720:Severity of Illness Index; D020554:Sperm Injections, Intracytoplasmic / Q000009:adverse effects