title: [Brain MR perfusion and MR spectroscopy in differentiation of radiation necrosis from tumor recurrence (case report)].
abstract: It is not always possible to differentiate tumor recurrence from radiation necrosis using conventional MR images. In this report we present a case of pathologically proven radiation necrosis which appeared as nodular contrast enhancement on conventional MR images in a patient who was surgically treated for grade II astrocytoma 5 years ago. There were decreased choline, creatine and N-acetyl aspartate peaks and significantly increased lipid peak on multivoxel H1-MR spectroscopy while there was no significant perfusion increase on MR perfusion. These findings suggested changes secondary to radiation necrosis.
authors.affiliation: Başkent Universitesi Tip Fakültesi, Radyoloji Anabilim Dali, Ankara, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Tekşam
authors.forename: Esra Meltem
authors.initials: EM
authors.lastname: Kayahan
authors.forename: Hasan
authors.initials: H
authors.lastname: Yerli
authors.forename: A Muhteşem
authors.initials: AM
authors.lastname: Ağildere
mesh_terms: D001254:Astrocytoma / Q000473:pathology*; D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D011832:Radiation Injuries / Q000473:pathology*