Gestrinone in the treatment of uterine leiomyomata: effects on uterine blood supply.
Gestrinone has been shown to reduce uterine volume and stop bleeding in women with uterine leiomyomata. In the present study, we demonstrated a reduction in the volume of uterine myomas and in the uterine artery blood perfusion over a 6-month period of gestrinone administration in premenopausal women.
La Marca
Antonio
A
Institute of Obstetrics and Gynecology, Universty of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy.
Giulini
Simone
S
Vito
Giovanni
G
Orvieto
Raoul
R
Volpe
Annibale
A
Jasonni
Valerio Maria
VM
D000328:Adult; D004965:Estrogen Antagonists / Q000627:therapeutic use*; D005260:Female; D005867:Gestrinone / Q000627:therapeutic use*; D006801:Humans; D018231:Leiomyomatosis / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000188:drug therapy*; D017697:Premenopause; D012039:Regional Blood Flow / Q000187:drug effects; D013997:Time Factors; D016896:Treatment Outcome; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000188:drug therapy*
D004965:Estrogen Antagonists; D005867:Gestrinone