title: Treatment efficacy research: a window into genetic and neurodevelopmental correlates of developmental disabilities.
abstract: This issue of MRDD research reviews is dedicated to treatment efficacy research. The treatment of MRDD conditions has long been a central question, but the clinical science of treatment efficacy has not yet been systematically applied to many MRDD typologies. The purpose of this paper is to provide an overview of this special issue and to provide a rationale for including treatment efficacy research as a tool for studying selected neurological development and genetic correlates of MRDD. Existing treatment efficacy paradigms should be applied systematically to relevant populations (and theoretical questions) and new, objectively tested paradigms should be developed in order to integrate ongoing discovery in MRDD.
authors.affiliation: Department of Hearing and Speech Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA. Stephen.m.camarata.2@vanderbilt.edu
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Camarata
authors.forename: Robert T
authors.initials: RT
authors.lastname: Wertz
mesh_terms: D001321:Autistic Disorder / Q000235:genetics / Q000628:therapy; D001921:Brain / Q000254:growth & development / Q000503:physiopathology; D002648:Child; D002658:Developmental Disabilities / Q000235:genetics / Q000628:therapy*; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics / Q000628:therapy*; D007805:Language Development Disorders / Q000235:genetics / Q000628:therapy; D007808:Language Therapy; D012107:Research Design; D016896:Treatment Outcome