Semiconductor quantum dots and free radical induced DNA nicking.
There is a growing interest in the use of semiconductor quantum dots as fluorescent markers in biological applications. However, there are concerns regarding the potential environmental impact and toxic nature of these nanomaterials. In this study, we have investigated the interaction of water-soluble semiconductor quantum dots with supercoiled DNA.
Green
Mark
M
Department of Physics, King's College London, Strand, London, UK WC2R 2LS. mark.a.green@kcl.ac.uk
Howman
Emily
E
D015374:Biosensing Techniques; D019187:Cadmium Compounds / Q000737:chemistry; D004278:DNA, Superhelical / Q000737:chemistry*; D005453:Fluorescence; D005609:Free Radicals / Q000737:chemistry*; D036103:Nanotechnology; D045663:Quantum Dots; D018036:Selenium Compounds / Q000737:chemistry; D012666:Semiconductors; D013440:Sulfides / Q000737:chemistry; D014867:Water / Q000737:chemistry*; D017967:Zinc Compounds / Q000737:chemistry
D019187:Cadmium Compounds; D004278:DNA, Superhelical; D005609:Free Radicals; D018036:Selenium Compounds; D013440:Sulfides; D017967:Zinc Compounds; D014867:Water; C031238:zinc sulfide