Guidelines and alternatives for neuraxial anesthesia and venous thromboembolism prophylaxis in major orthopedic surgery.
Neuraxial anesthesia during major orthopedic surgery, combined with venous thromboembolism prophylaxis, is generally safe and well tolerated, with potential benefits over general anesthesia. The risk of spinal/epidural hematoma, a rare but very serious complication, can be minimized by careful patient selection and attention to anesthetic technique. This risk is further reduced with the use of peripheral nerve blocks in place of neuraxial anesthesia.
Hantler
Charles
C
Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Despotis
George J
GJ
Sinha
Raj
R
Chelly
Jacques E
JE
D000765:Anesthesia, Conduction / Q000009:adverse effects / Q000379:methods*; D000768:Anesthesia, General; D001241:Aspirin / Q000627:therapeutic use; D065427:Factor Xa Inhibitors; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D019637:Orthopedic Procedures; D020246:Venous Thrombosis / Q000517:prevention & control*; D014812:Vitamin K / Q000037:antagonists & inhibitors; D014859:Warfarin / Q000494:pharmacology
D065427:Factor Xa Inhibitors; D014812:Vitamin K; D014859:Warfarin; D006493:Heparin; D001241:Aspirin