title: May 2004: newborn with intracranial mass.
abstract: May 2004: We present the case of a male newborn (38th week of gestation) with a 3-week history of a sonographically detected parietal mass of 5-cm diameter. The entire mass was removed at surgery. Surprisingly, microscopy revealed an intracerebral hemorrhage and nests of glycophorin-A immunoreactive blasts and nucleated erythrocytes in the surrounding parenchyma. The final diagnosis was chronic intracerebral hemorrhage of unknown etiology with reactive changes of the surrounding brain tissue and perifocal extramedullary erythropoiesis. This case is unique because, to date, intracranial extramedullary erythropoiesis has only been described in chronic subdural hemorrhage.
authors.affiliation: Institute of Pathology, Laboratory of Neuropathology, University Hospitals of Ulm, Germany.
authors.forename: Stefanie
authors.initials: S
authors.lastname: Scheil
authors.forename: Torsten
authors.initials: T
authors.lastname: Horn
authors.forename: Ulrich
authors.initials: U
authors.lastname: Kunz
authors.forename: Andreas
authors.initials: A
authors.lastname: Gabelmann
authors.forename: Anna-Leena
authors.initials: AL
authors.lastname: Sirén
authors.forename: Rüdiger
authors.initials: R
authors.lastname: Klein
authors.forename: Christoph
authors.initials: C
authors.lastname: Schindler
authors.forename: Peter
authors.initials: P
authors.lastname: Möller
authors.forename: Clemens
authors.initials: C
authors.lastname: Sommer
mesh_terms: D002493:Central Nervous System Diseases / Q000378:metabolism / Q000473:pathology*; D002543:Cerebral Hemorrhage / Q000378:metabolism / Q000473:pathology*; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D016708:Synaptophysin / Q000378:metabolism
chemical_list: D005904:Glial Fibrillary Acidic Protein; D016708:Synaptophysin