title: Severe tick borne encephalitis with simultaneous brain stem, bithalamic, and spinal cord involvement documented by MRI.
abstract: A case of tick borne encephalitis (TBE) is reported, with simultaneous brain stem, spinal cord, and bilateral thalamic involvement confirmed by magnetic resonance imaging (MRI). After exposure to a TBE endemic region, the patient developed a biphasic clinical course with initial flu-like symptoms followed by a severe brain stem syndrome. The diagnosis of TBE was confirmed serologically. Repeated MRI scans showed brain stem, bithalamic, and spinal cord involvement. The outcome was favourable. TBE cases with concomitant myelitis tend to have a more severe clinical course and more likelihood of needing intensive care support. They should therefore be identified early in order to be prepared for life threatening respiratory complications.
authors.affiliation: Department of Neurology, University of Munich, Klinikum Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany. andreas.bender@med.uni-muenchen.de
authors.forename: A
authors.initials: A
authors.lastname: Bender
authors.forename: G
authors.initials: G
authors.lastname: Schulte-Altedorneburg
authors.forename: E U
authors.initials: EU
authors.lastname: Walther
authors.forename: H-W
authors.initials: HW
authors.lastname: Pfister
mesh_terms: D000328:Adult; D001933:Brain Stem / Q000473:pathology*; D004669:Encephalitis Viruses, Tick-Borne; D004675:Encephalitis, Tick-Borne / Q000473:pathology*; D006801:Humans; D008297:Male; D009187:Myelitis / Q000473:pathology* / Q000821:virology; D012720:Severity of Illness Index; D013788:Thalamus / Q000473:pathology*