Would Sacaca, Croton cajucara Benth (Euphorbiaceae) be an hepatotoxic plant like Germander, Teucrium chamaedrys L. (Labiatae)?
Clinical and experimental studies have consistently incriminated the medicinal plant germander (Teucrium chamaedrys L.) in epidemic and sporadic cases of liver diseases. The sacaca (Croton cajucara Benth), a common plant in Brazilian Amazon region also comes being incriminated in similar clinical cases. Of both plants were isolated diterpenoid compounds with similar chemical structures.
Soares
Manoel do Carmo Pereira
Mdo C
Instituto Evandro Chagas da Secretaria de Vigilância em Saúde do Ministério da saúde. msoares@iec.pa.gov.br
D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D029802:Croton / Q000737:chemistry / Q000633:toxicity*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D006801:Humans; D031367:Teucrium / Q000737:chemistry / Q000633:toxicity*
D004224:Diterpenes