title: An orphan receptor adopted by a family of transmitters.
abstract: A tenet of pharmacology states that a receptor must be selective for and bind its natural ligand with high affinity. Recently discovered ligands of some deorphanized G protein-coupled receptors challenge this concept.
authors.affiliation: Department of Pharmacology, University of California, Irvine, Med Surge II, Room 369, Irvine, CA 92697-4625, USA. ocivelli@uci.edu
authors.forename: Olivier
authors.initials: O
authors.lastname: Civelli
mesh_terms: D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000502:physiology; D006801:Humans; D043562:Receptors, G-Protein-Coupled / Q000502:physiology*
chemical_list: D000596:Amino Acids; C488584:GPRC6A protein, human; D043562:Receptors, G-Protein-Coupled