title: Chemical composition, antibacterial and antifungal activities of the essential oil of Haplophyllum tuberculatum from Oman.
abstract: The chemical composition of the essential oil of Haplophyllum tuberculatum (Forsskal) A. Juss (Rutaceae) was analyzed by gas chromatography-mass spectral (GC-MS) and 13C NMR spectroscopy. Thirty compounds, constituting about 99.7% of the total oil, were identified. The most abundant oil components are beta-phellandrene (23.3%), limonene (12.6%), (Z)-beta-ocimene (12.3%), beta-caryophyllene (11.6%), myrcene (11.3%), and alpha-phellandrene (10.9%). Ten microlitres (25 mg) of pure oil partially inhibited the growth of Escherichia coli, Salmonella choleraesuis, and Bacillus subtilis to the same extent as 0.10 microg of gentamycin sulfate. The oil also affected the mycelial growth of Curvularia lunata and Fusarium oxysporium in a dose-dependent manner but had no effect on the germination of their spores.
authors.affiliation: Department of Chemistry, College of Science, Sultan Qaboos University, PO Box 36, Al-Khod-123, Muscat, Sultanate of Oman.
authors.forename: Suad Khamis S
authors.initials: SK
authors.lastname: Al-Burtamani
authors.forename: Majekodunmi O
authors.initials: MO
authors.lastname: Fatope
authors.forename: Ruchi G
authors.initials: RG
authors.lastname: Marwah
authors.forename: Anthony K
authors.initials: AK
authors.lastname: Onifade
authors.forename: Salim H
authors.initials: SH
authors.lastname: Al-Saidi
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry*; D000935:Antifungal Agents / Q000737:chemistry*; D035264:Flowers / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D006090:Gram-Negative Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects; D009822:Oils, Volatile / Q000737:chemistry*; D009850:Oman; D010936:Plant Extracts / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D027821:Rutaceae / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D009822:Oils, Volatile; D010936:Plant Extracts