title: [A case of nodular regenerative hyperplasia of liver that mimicked primary biliary cirrhosis].
abstract: Nodular regenerative hyperplasia (NRH) of the liver is a rare disease that is characterized by multiple regenerative nodules in the hepatic parenchyma without fibrosis. The exact pathogenesis of NRH has not been established, but it's been suggested that obliteration of portal veins may initiate the nodular transformation. It is also known that this disease is associated with autoimmune disease, myeloproliferative disease, lymphoproliferative disease, primary biliary cirrhosis, and some chemotherapy agents. The patients with NRH are usually asymptomatic, yet if they have symptoms, the most common clinical manifestations are those of portal hypertension, including splenomegaly and esophageal varices with or without bleeding. We report a case of nodular regenerative hyperplasia that presented with clinical manifestations similar to those of primary biliary cirrhosis.
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Korea.
authors.forename: Sung Gon
authors.initials: SG
authors.lastname: Shim
authors.forename: Joo Hyun
authors.initials: JH
authors.lastname: Sohn
authors.forename: Jae Woong
authors.initials: JW
authors.lastname: Lee
authors.forename: Young Woo
authors.initials: YW
authors.lastname: Chung
authors.forename: Chang Hee
authors.initials: CH
authors.lastname: Paik
authors.forename: Jong Pyo
authors.initials: JP
authors.lastname: Kim
authors.forename: Yong Chul
authors.initials: YC
authors.lastname: Jeon
authors.forename: Dong Soo
authors.initials: DS
authors.lastname: Han
authors.forename: Joon Soo
authors.initials: JS
authors.lastname: Hahm
authors.forename: Dong Hoo
authors.initials: DH
authors.lastname: Lee
authors.forename: Choon Suhk
authors.initials: CS
authors.lastname: Kee
authors.forename: Young Ha
authors.initials: YH
authors.lastname: Oh
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D006965:Hyperplasia; D008099:Liver / Q000473:pathology*; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis*