title: Transient visual loss after amyl Isobutyl nitrite abuse.
abstract: OBJECTIVE
  To report retinal alterations after Isobutyl nitrite (popper) inhalation.
  
  
  METHODS
  Case Report.
  
  
  RESULTS
  A 30-year-old man presented a sudden visual decrease following the use of Isobutyl nitrite (popper) while he was at a discotheque. His visual acuity (VA) was 20/50 in the right eye (RE) and 20/63 in the left eye (LE). Ophthalmoscopy revealed symmetric alteration of the foveal reflex with a small yellowish-white spot in the foveal area, much more evident in the RE. Fluorescein angiography and OCT were normal. Visual field showed a mild reduction of central differential light sensitivity. A progressive recovery was noted and at one month's follow-up VA was 20/25 in OU with very faint yellowish-white spots.
  
  
  CONCLUSIONS
  The inhalation of drugs as "popper" may cause a visual loss by unclear mechanisms.
authors.affiliation: Clinica Oculistica, Ospedale di Melegnano, Vizzolo Predabissi, Italy. pece.retina@mclink.it
authors.forename: Alfredo
authors.initials: A
authors.lastname: Pece
authors.forename: Fabio
authors.initials: F
authors.lastname: Patelli
authors.forename: Paolo
authors.initials: P
authors.lastname: Milani
authors.forename: Luisa
authors.initials: L
authors.lastname: Pierro
mesh_terms: D000328:Adult; D000680:Amyl Nitrite / Q000009:adverse effects*; D001766:Blindness / Q000139:chemically induced* / Q000503:physiopathology; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D012160:Retina / Q000187:drug effects* / Q000503:physiopathology; D041623:Tomography, Optical Coherence; D014665:Vasodilator Agents / Q000009:adverse effects*; D014794:Visual Fields / Q000187:drug effects
chemical_list: D014665:Vasodilator Agents; D000680:Amyl Nitrite