Light-induced inhibition of chymotrypsin using photocleavable monolayers on gold nanoparticles.
Positively charged gold nanoparticles featuring photocleavable units within their surrounding monolayer are switched from non-interacting species to inhibitors of chymotrypsin through UV irradiation.
Fischer
Nicholas O
NO
Department of Chemistry, The University of Massachusetts, Amherst, MA 01003, USA.
Paulini
Ralph
R
Drechsler
Ulf
U
Rotello
Vincent M
VM
D002918:Chymotrypsin / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006046:Gold / Q000737:chemistry*; D015394:Molecular Structure; D049329:Nanostructures / Q000737:chemistry*; D010777:Photochemistry; D013053:Spectrophotometry; D014466:Ultraviolet Rays
D006046:Gold; D002918:Chymotrypsin