Identification of an expressed gene in Dipylidium caninum.
Recombinant DNA studies have been focused on developing vaccines to different cestodes. But few studies involving Dipylidium caninum molecular biology and genes have been done. Only partial sequences of mitochondrial DNA and ribosomal RNA gene are available in databases. Any molecular work with this parasite, including epidemiology, study of drug-resistant strains, and vaccine development, is hampered by the lack of knowledge of its genome. Thus, the knowledge of specific genes of different developmental stages of D. caninum is crucial to locate potential targets to be used as candidates to develop a vaccine and/or new drugs against this parasite. Here we report, for the first time, the sequencing of a fragment of a D. caninum expressed gene.
Miranda
Rodrigo R C
RR
Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Costa-Júnior
Livio M
LM
Campos
Artur K
AK
Santos
Hudson A
HA
Rabelo
Elida M L
EM
D000818:Animals; D002589:Cestoda / Q000235:genetics* / Q000472:pathogenicity*; D002590:Cestode Infections / Q000235:genetics*; D004283:Dog Diseases / Q000235:genetics* / Q000469:parasitology*; D004285:Dogs; D020869:Gene Expression Profiling; D009245:NADH Dehydrogenase / Q000235:genetics; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D014612:Vaccines
D014612:Vaccines; D009245:NADH Dehydrogenase