title: Renal angiomyolipoma in Japanese tuberous sclerosis patients.
abstract: OBJECTIVE
  Renal angiomyolipoma (AML) is a benign neoplasm that may grow massive in tuberous sclerosis (TS) patients. The aim of this study was to document the characteristics of renal AML in Japanese TS patients.
  
  
  METHODS
  Medical records of 29 TS patients followed up at the authors' center were reviewed for the presence, size, symptom, and treatment of renal AML.
  
  
  RESULTS
  Twenty-four patients screened for renal AML were subdivided into 4 groups: group 0 (n = 8), no mass; group 1 (n = 5), AML less than 1 cm in diameter; group 2 (n = 4), AML 1 to 4 cm in diameter; group 3 (n = 7), AML greater than 4 cm in diameter. When present, AML always affected both kidneys and were multiple. All patients in groups 1 and 2 were symptom free, and the tumors seemed stable in size. All tumors in group 3 grew progressively causing various symptoms. Total or partial nephrectomy or transarterial embolization was performed in 5 patients with limited success.
  
  
  CONCLUSIONS
  AML in TS patients can be stable or aggressive. Pediatric surgeons aware of this problem should be involved in a follow-up program.
authors.affiliation: Department of Surgery, National Center for hild Health and Development, Tokyo, Japan.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Kitano
authors.forename: Toshiro
authors.initials: T
authors.lastname: Honna
authors.forename: Kenji
authors.initials: K
authors.lastname: Nihei
authors.forename: Jun
authors.initials: J
authors.lastname: Miyauchi
authors.forename: Kentarou
authors.initials: K
authors.lastname: Matsuoka
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Kuroda
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Tanaka
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Morikawa
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Fuchimoto
mesh_terms: D000293:Adolescent; D000328:Adult; D018207:Angiomyolipoma / Q000150:complications*; D002648:Child; D005260:Female; D006801:Humans; D007564:Japan; D007680:Kidney Neoplasms / Q000150:complications*; D008297:Male; D012189:Retrospective Studies; D014402:Tuberous Sclerosis / Q000150:complications*