title: In vivo induced antigen technology (IVIAT).
abstract: In vivo induced antigen technology (IVIAT) is a technique that identifies pathogen antigens that are immunogenic and expressed in vivo during human infection. IVIAT is complementary to other techniques that identify genes and their products expressed in vivo. Genes and gene pathways identified by IVIAT may play a role in virulence or pathogenesis during human infection, and may be appropriate for inclusion in therapeutic, vaccine or diagnostic applications.
authors.affiliation: Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA.
authors.forename: Sean M
authors.initials: SM
authors.lastname: Rollins
authors.forename: Amanda
authors.initials: A
authors.lastname: Peppercorn
authors.forename: Long
authors.initials: L
authors.lastname: Hang
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Hillman
authors.forename: Stephen B
authors.initials: SB
authors.lastname: Calderwood
authors.forename: Martin
authors.initials: M
authors.lastname: Handfield
authors.forename: Edward T
authors.initials: ET
authors.lastname: Ryan
mesh_terms: D000941:Antigens / Q000032:analysis* / Q000096:biosynthesis; D005786:Gene Expression Regulation; D015723:Gene Library; D006801:Humans; D007158:Immunologic Techniques; D007239:Infections / Q000276:immunology / Q000382:microbiology
chemical_list: D000941:Antigens