title: [Safety assessment of GM yeast feed additive with cecropin CAD gene].
abstract: OBJECTIVE
  To evaluate the safety of GM yeast feed additive with cecropin CAD and to study and set up a model of Safety assessment for GM feed and detecting method.
  
  
  METHODS
  To ensure the safety of the GM products, it has been done that to detect and value the safety of receptor organisms and expression products of extrinsic gene, the genetic stability of biologic properties of genomic modified yeast feed and condition of transfer and cumulation of anti-bacterial peptide and its products in circumstance and the feeded animals.
  
  
  CONCLUSIONS
  The receptor animals and expression products of extrinic gene are safe, and the genomic modified products have steady genetic characters. The cectopin CAD neither cumulates in feeded animal nor releases into environment. The genomic modified feed additive is safe.
authors.affiliation: Shenzhen Center for Disease Control and Prevention, Shenzhen 518020, China.
authors.forename: Pingjian
authors.initials: P
authors.lastname: Deng
authors.forename: Shisong
authors.initials: S
authors.lastname: Fang
authors.forename: Dongyan
authors.initials: D
authors.lastname: Yang
authors.forename: Lihua
authors.initials: L
authors.lastname: Jiang
authors.forename: Xiangqiang
authors.initials: X
authors.lastname: Yu
authors.forename: Yongbin
authors.initials: Y
authors.lastname: Huang
authors.forename: Ziran
authors.initials: Z
authors.lastname: Huang
mesh_terms: D000821:Animal Feed / Q000633:toxicity*; D000818:Animals; D023181:Antimicrobial Cationic Peptides / Q000235:genetics / Q000378:metabolism*; D002645:Chickens; D033364:Decapoda; D005503:Food Additives / Q000633:toxicity*; D030841:Food, Genetically Modified / Q000633:toxicity*; D051379:Mice; D030781:Organisms, Genetically Modified; D018570:Risk Assessment; D012449:Safety; D013552:Swine; D018675:Toxicity Tests; D015003:Yeasts / Q000235:genetics* / Q000378:metabolism
chemical_list: D023181:Antimicrobial Cationic Peptides; D005503:Food Additives