title: The Vertebrate Genome Annotation (Vega) database.
abstract: The Vertebrate Genome Annotation (Vega) database (http://vega.sanger.ac.uk) has been designed to be a community resource for browsing manual annotation of finished sequences from a variety of vertebrate genomes. Its core database is based on an Ensembl-style schema, extended to incorporate curation-specific metadata. In collaboration with the genome sequencing centres, Vega attempts to present consistent high-quality annotation of the published human chromosome sequences. In addition, it is also possible to view various finished regions from other vertebrates, including mouse and zebrafish. Vega displays only manually annotated gene structures built using transcriptional evidence, which can be examined in the browser. Attempts have been made to standardize the annotation procedure across each vertebrate genome, which should aid comparative analysis of orthologues across the different finished regions.
authors.affiliation: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK. jla1@sanger.ac.uk
authors.forename: J L
authors.initials: JL
authors.lastname: Ashurst
authors.forename: C-K
authors.initials: CK
authors.lastname: Chen
authors.forename: J G R
authors.initials: JG
authors.lastname: Gilbert
authors.forename: K
authors.initials: K
authors.lastname: Jekosch
authors.forename: S
authors.initials: S
authors.lastname: Keenan
authors.forename: P
authors.initials: P
authors.lastname: Meidl
authors.forename: S M
authors.initials: SM
authors.lastname: Searle
authors.forename: J
authors.initials: J
authors.lastname: Stalker
authors.forename: R
authors.initials: R
authors.lastname: Storey
authors.forename: S
authors.initials: S
authors.lastname: Trevanion
authors.forename: L
authors.initials: L
authors.lastname: Wilming
authors.forename: T
authors.initials: T
authors.lastname: Hubbard
mesh_terms: D000818:Animals; D002877:Chromosomes, Human / Q000737:chemistry; D003628:Database Management Systems; D030541:Databases, Genetic / Q000592:standards; D016678:Genome; D023281:Genomics; D006801:Humans; D051379:Mice; D014584:User-Computer Interface; D014714:Vertebrates / Q000235:genetics*; D015027:Zebrafish / Q000235:genetics