Synthesis and hetero-Michael addition reactions of 2-alkynyl oxazoles and oxazolines.
Stereoselective conjugate additions of alcohols, amines, thiols, and halides to C(2)-alkynyl oxazoles and oxazolines provide a versatile entry to heterocyclic building blocks.
Wipf
Peter
P
Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA. pwipf@pitt.edu
Graham
Thomas H
TH
D015394:Molecular Structure; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry; D010081:Oxazolone / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
D010080:Oxazoles; D010081:Oxazolone