title: Outcomes after pylorus-preserving gastrectomy for early gastric cancer: a prospective multicenter trial.
abstract: The aim of the present study was to compare in a prospective, multicenter trial the results early and late after pylorus-preserving gastrectomy (PPG) versus conventional distal gastrectomy (CDG) with Billroth I anastomosis for early gastric cancer. Eighty-one patients with early gastric cancer were randomized and then underwent either PPG or CDG. Duration of operation, intraoperative blood loss, days until removal of the nasogastric tube, days until start of oral intake, and decrease in body weight were studied as parameters for outcomes early after the surgery. Late results were studied in patients followed for longer than 3 years. Change in body weight, status of oral intake, symptoms suggesting early dumping syndrome, and overall satisfaction were addressed in the questionnaire. The presence of gallstones was examined with ultrasonography. There were no differences in early results between PPG and CDG. The incidence of early dumping syndrome was lower in PPG (8%) than in CDG (33%). Other late results including the incidence of gallstones were not different between the 2 groups. These results indicate that PPG is as safe as CDG and has an advantage in terms of early dumping syndrome.
authors.affiliation: Department of Surgery, Tohoku University School of Medicine, Seiryo-machi, 980-8574 Aoba-ku, Sendai, Japan. cshibata@gonryo.med.tohoku.ac.jp
authors.forename: Chikashi
authors.initials: C
authors.lastname: Shibata
authors.forename: Ken-ichí
authors.initials: KI
authors.lastname: Shiiba
authors.forename: Yuji
authors.initials: Y
authors.lastname: Funayama
authors.forename: Seiichi
authors.initials: S
authors.lastname: Ishii
authors.forename: Kouhei
authors.initials: K
authors.lastname: Fukushima
authors.forename: Takayuki
authors.initials: T
authors.lastname: Mizoi
authors.forename: Kaori
authors.initials: K
authors.lastname: Koyama
authors.forename: Koh
authors.initials: K
authors.lastname: Miura
authors.forename: Seiki
authors.initials: S
authors.lastname: Matsuno
authors.forename: Hiroo
authors.initials: H
authors.lastname: Naito
authors.forename: Eiichi
authors.initials: E
authors.lastname: Kato
authors.forename: Tsuyohiko
authors.initials: T
authors.lastname: Honda
authors.forename: Satoshi
authors.initials: S
authors.lastname: Momono
authors.forename: Akio
authors.initials: A
authors.lastname: Ouchi
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Ashino
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Tsuneaki
authors.initials: T
authors.lastname: Fujiya
authors.forename: Akihiro
authors.initials: A
authors.lastname: Iwatsuki
authors.forename: Iwao
authors.initials: I
authors.lastname: Sasaki
mesh_terms: D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011708:Pylorus; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome