title: Health-related quality of life outcome for oral cancer survivors after surgery and postoperative radiotherapy.
abstract: BACKGROUND
  Health-related quality of life (HRQL) data are becoming an important supplement to information pertaining to treatment outcome for cancer patients. The purpose of this study was to evaluate the HRQL outcome for oral cancer survivors after surgery plus postoperative radiotherapy (RT) and to investigate the variables associated with their HRQL.
  
  
  METHODS
  Sixty-six oral cancer patients with cancer-free survival after surgery plus postoperative RT of >2 years were enrolled. The Short Form-36 (SF-36) questionnaire in the Taiwan Chinese version was self-reported by all participants at the clinics. The linear regression model was used to analyze the socio-demographic and medical-related variables correlated with the physical component summary (PCS) and mental component summary (MCS) in SF-36.
  
  
  RESULTS
  The mean scores of the eight functional domains in the SF-36 were markedly lower for oral cancer survivors compared with the Taiwanese and US norms. Those with older age, lower annual family income, more advanced cancer stage and flap reconstruction had significantly worse PCS, and those with lower annual family income, unemployment and more advanced cancer stage reported significantly worse MCS. This model accounts for 63% of variance in PCS, and 51% in MCS.
  
  
  CONCLUSIONS
  These results provided patient-reported evidence that oral cancer survivors lived with a worse HRQL compared with the general Taiwanese population. Socio-economic factors and cancer stage were important factors correlated with their HRQL.
authors.affiliation: Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital, 123 Ta-Pei Rd, Niao Sung Hsiang, Kaohsiung Hsien, Taiwan. a7323630@ms14.hinet.net
authors.forename: Fu-Min
authors.initials: FM
authors.lastname: Fang
authors.forename: Wen-Ling
authors.initials: WL
authors.lastname: Tsai
authors.forename: Chih-Yen
authors.initials: CY
authors.lastname: Chien
authors.forename: Herng-Chia
authors.initials: HC
authors.lastname: Chiu
authors.forename: Chong-Jong
authors.initials: CJ
authors.lastname: Wang
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D003430:Cross-Sectional Studies; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000523:psychology* / Q000532:radiotherapy* / Q000601:surgery; D011184:Postoperative Period; D011788:Quality of Life; D011795:Surveys and Questionnaires; D017741:Survivors; D016896:Treatment Outcome