title: Treatment of pain symptoms in irritable bowel syndrome patients.
abstract: Irritable bowel syndrome represents a common gastrointestinal disorder that significantly impacts patients' lives. It is defined by Rome II criteria and characterized by abdominal pain and bloating associated with changes in bowel habit. Visceral hypersensitivity is currently considered a biological marker for the disease. Current therapeutic treatments include the use of fiber supplements, antidiarrheal agents, laxatives, antispasmodics, tricyclic antidepressants and serotonergic agents. Through a proper understanding of the diagnostic criteria, pathophysiology and treatment options, this disorder can be treated effectively in many patients.
authors.affiliation: University of Florida, Department of Medicine, Division of Gastroenterology, Gainesville, Florida 32608, USA.
authors.forename: Vishal
authors.initials: V
authors.lastname: Gupta
authors.forename: Baharak
authors.initials: B
authors.lastname: Moshiree
authors.forename: G Nicholas
authors.initials: GN
authors.lastname: Verne
mesh_terms: D015746:Abdominal Pain / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D004043:Dietary Fiber / Q000145:classification / Q000494:pharmacology; D004334:Drug Administration Schedule; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D015337:Multicenter Studies as Topic; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000145:classification; D016032:Randomized Controlled Trials as Topic
chemical_list: D004043:Dietary Fiber; D004364:Pharmaceutical Preparations