Helicobacter cinaedi bacteremia presenting as macules in an afebrile patient with X-linked agammaglobulinemia.
We describe a 54-year-old man with X-linked agammaglobulinemia (XLA) and Helicobacter cinaedi bacteremia, who presented with tender, hyper-pigmented skin macules without increased local warmth or fever. We propose that this presentation may be a characteristic early sign of bacteremia caused by H. cinaedi and related organisms in otherwise healthy immunocompromised patients. This case demonstrates the importance of a high index of suspicion for H. cinaedi bacteremia in immunocompromised patients with unexplained skin lesions.
Simons
E
E
Dept. of Pediatrics, The Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, 600 N. Wolfe Street, CMSC 1102, Baltimore, MD 21287-3923, USA. esimons@medscape.com
Spacek
L A
LA
Lederman
H M
HM
Winkelstein
J A
JA
D000361:Agammaglobulinemia / Q000150:complications / Q000235:genetics* / Q000382:microbiology*; D016470:Bacteremia / Q000209:etiology* / Q000473:pathology; D040181:Genetic Diseases, X-Linked / Q000150:complications / Q000235:genetics* / Q000382:microbiology*; D016998:Helicobacter / Q000472:pathogenicity*; D016481:Helicobacter Infections / Q000209:etiology* / Q000473:pathology; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged