Plantar hyperhidrosis and pitted keratolysis treated with botulinum toxin injection.
BACKGROUND
Sulcate plantare keratolysis or pitted keratolysis (plantar keratolysis sulcatum) is a disease that is commonly found in tropical countries. Patients have also reported plantar hyperhidrosis.


OBJECTIVE
Two patients with pitted keratolysis resistant to topical and systemic treatments are described.


METHODS
Both patients were injected with botulinum toxin distributed evenly through the plantar extension.


RESULTS
The response to the treatment was excellent despite using a low dose of botulinum toxin with the plantar keratolysis healing completely.


CONCLUSIONS
Hyperhidrosis may be considered the major etiologic factor for pitted keratolysis that does not respond to treatment.
Tamura
Bhertha M
BM
General Hospital of the Medical School of the University of São Paulo, São Paulo, Brazil. tamurab@uol.com.br
Cucé
Luiz Carlos
LC
Souza
Raquel Leão
RL
Levites
Jacob
J
D000328:Adult; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D005260:Female; D005533:Foot Dermatoses / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D006945:Hyperhidrosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D007271:Injections, Intradermal; D008297:Male
D003879:Dermatologic Agents; D019274:Botulinum Toxins, Type A