Increased sensitivity and confidence of SPECT over planar imaging in dual-phase sestamibi for parathyroid adenoma detection.
PURPOSE OF REPORT: To determine the usefulness of SPECT imaging over planar imaging for the detection of parathyroid adenomas using dual-phase Tc-99m sestamibi.


METHODS
The records of patients referred for dual-phase sestamibi scintigraphy for detection of parathyroid adenomas were reviewed retrospectively. The images were reviewed blindly and planar images were compared with SPECT. The imaging results were compared with the operative results to determine the sensitivity, accuracy of localization, and confidence of the reporting radiologist.


RESULTS
The records of 37 patients were reviewed. Sensitivity was 62% for planar imaging and 73% for SPECT. There was one false positive. The side of the adenoma was correctly identified in all other patients. Confidence of detection was higher for SPECT than for planar imaging.


CONCLUSIONS
SPECT imaging increased the sensitivity and confidence of the detection of parathyroid adenomas. The results indicate that SPECT should be used for all preoperative parathyroid localization.
Slater
Andrew
A
Department of Radiology, The Churchill Hospital, Oxford, UK. andrewslater99@hotmail.com
Gleeson
Fergus V
FV
D000236:Adenoma / Q000000981:diagnostic imaging*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D016037:Single-Blind Method; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi