title: Effect of probiotic containing Saccharomyces boulardii on experimental ochratoxicosis in broilers: hematobiochemical studies.
abstract: In the present investigation, the toxicopathological effects of ochratoxin A of 0.5 ppm on hematobiochemical parameters of broilers were studied with efficacy of dietary concentration of probiotic containing yeast culture Saccharomyces boulardii of 10 mg/kg of feed. One hundred twenty day old chicks were randomly divided into four groups, thirty chicks each. Groups A and C chicks were offered normal feed and that added with probiotic Saccharomyces boulardii respectively. The birds in group B were fed ochratoxin A of 0.5 ppm of feed. Where as, the birds of group D, were fed with ochratoxin A of 0.5 ppm along with probiotic Saccharomyces boulardii of 10 mg/kg of diet. Hematological studies carried revealed significant decrease in the haemoglobin and packed cell volume in birds of group B and reduced effect in birds of group D due to probiotic. Biochemical profiles revealed significant improvement in probiotic treated group D when compared with decreased values of Total protein, albumin, globulin and increased levels of serum creatinine and SGPT in birds of groups B.
authors.affiliation: Department of Pathology, Bombay Veterinary College, Mumbai, India. drsachinagawane@yahoo.com
authors.forename: S B
authors.initials: SB
authors.lastname: Agawane
authors.forename: P S
authors.initials: PS
authors.lastname: Lonkar
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000821:Animal Feed; D000818:Animals; D002273:Carcinogens / Q000633:toxicity*; D002645:Chickens / Q000097:blood; D003404:Creatinine / Q000097:blood; D006400:Hematocrit / Q000662:veterinary; D015651:Mycotoxicosis / Q000097:blood / Q000517:prevention & control / Q000662:veterinary*; D009793:Ochratoxins / Q000633:toxicity*; D011201:Poultry Diseases / Q000097:blood / Q000517:prevention & control*; D019936:Probiotics / Q000627:therapeutic use*; D012440:Saccharomyces / Q000502:physiology*
chemical_list: D002273:Carcinogens; D009793:Ochratoxins; C025589:ochratoxin A; D003404:Creatinine; D000410:Alanine Transaminase