title: Cyclization of 1-bromo-2,7- and 1-bromo-2,8-enynes mediated by indium.
abstract: [reaction: see text] The cyclization of 1-bromo-2,7- and 1-bromo-2,8-enynes mediated by indium in DMF produced five- and six-membered cyclic compounds. Although KI was a necessary additive in the cyclization of terminal 1-bromo-2,7-enynes to give the desired products at 25 degrees C, reactions of terminal 1-bromo-2,8-enynes and internal 1-bromo-2,7-enynes with indium proceeded at 100 degrees C in DMF without KI. After cyclizations, subsequent cross-coupling reaction and iodolysis increase the usefulness of this reaction.
authors.affiliation: Department of Chemistry, Kangwon National University, Chunchon 200-701, Republic of Korea. phlee@kangwon.ac.kr
authors.forename: Phil Ho
authors.initials: PH
authors.lastname: Lee
authors.forename: Sundae
authors.initials: S
authors.lastname: Kim
authors.forename: Kooyeon
authors.initials: K
authors.lastname: Lee
authors.forename: Dong
authors.initials: D
authors.lastname: Seomoon
authors.forename: Hyunseok
authors.initials: H
authors.lastname: Kim
authors.forename: Seokju
authors.initials: S
authors.lastname: Lee
authors.forename: Misook
authors.initials: M
authors.lastname: Kim
authors.forename: Mijeong
authors.initials: M
authors.lastname: Han
authors.forename: Kwanghyun
authors.initials: K
authors.lastname: Noh
authors.forename: Tom
authors.initials: T
authors.lastname: Livinghouse