An unusual mastocytoma with massive eosinophilic infiltration: identification with immunohistochemistry.
A cutaneous mastocytoma excised from a 6-month-old male infant was found to have unusual massive eosinophilic infiltrates. The mast cells were identified with the aid of immunohistochemistry with antibodies to tryptase and KIT protein (CD117). Massive eosinophilic infiltration in a cutaneous tumor could be a diagnostic clue of an eosinophil-rich mastocytoma.
Ueng
Shir-Hwa
SH
Department of Pathology, Chang Gung Memorial Hospital, Taipei 105, Taiwan.
Kuo
Tseng-tong
TT
D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008297:Male; D034801:Mastocytoma / Q000378:metabolism* / Q000473:pathology; D019009:Proto-Oncogene Proteins c-kit / Q000378:metabolism; D012878:Skin Neoplasms / Q000378:metabolism* / Q000473:pathology
D019009:Proto-Oncogene Proteins c-kit