Distribution of antimicrobial resistance and virulence-related genes among Brazilian group B streptococci recovered from bovine and human sources.
In the present report we describe the characteristics of 189 antimicrobial-resistant Streptococcus agalactiae isolates from bovine (38 isolates) and human (151 isolates) sources. All the strains were resistant to tetracycline (TET), and 16 (8.5%) were also resistant to erythromycin, corresponding to 23.7% of the TET-resistant bovine isolates and 4.6% of the TET-resistant human isolates. The tet(O), erm(B), and mreA resistance-related genes, as well as the bca and scpB virulence-related genes, were the most frequent among the bovine isolates, while the tet(M), erm(A), mreA, bca, lmb, and scpB genes were the most prevalent among the isolates from humans. Although a few major clusters were observed, pulsed-field gel electrophoresis results revealed a variety of profiles, reflecting the substantial genetic diversity among strains of this species isolated from either humans or bovines.
Duarte
Rafael S
RS
Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, CCS, Bloco I, Cidade Universitária, Rio de Janeiro, RJ 21941-590, Brazil.
Bellei
Bruna C
BC
Miranda
Otávio P
OP
Brito
Maria A V P
MA
Teixeira
Lúcia M
LM
D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics*; D001938:Brazil / Q000453:epidemiology; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology / Q000382:microbiology; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D016521:Electrophoresis, Gel, Pulsed-Field; D004917:Erythromycin / Q000494:pharmacology; D005260:Female; D006801:Humans; D008414:Mastitis, Bovine / Q000453:epidemiology / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D013290:Streptococcal Infections / Q000453:epidemiology / Q000382:microbiology*; D013292:Streptococcus agalactiae / Q000187:drug effects / Q000235:genetics / Q000472:pathogenicity*; D013752:Tetracycline / Q000494:pharmacology; D014774:Virulence / Q000235:genetics
D001426:Bacterial Proteins; D004917:Erythromycin; D013752:Tetracycline