title: Peripheral odontogenic keratocyst: report of two cases and review of the literature.
abstract: The odontogenic keratocyst is a developmental odontogenic cyst most commonly occurring in the jaws. In rare instances, however, this lesion has been reported to occur in the gingival soft tissues. Although most authors have regarded these soft tissue lesions to be peripheral odontogenic keratocysts, others have preferred to regard them as histopathologic variants of the gingival cyst of the adult. We document 2 additional cases occurring in the gingival soft tissues, and we review the existing literature concerning this unusual lesion. Given the distinct microscopic features and possible association with nevoid basal cell carcinoma syndrome, we favor the view that this lesion represents the soft tissue counterpart of the intraosseous odontogenic keratocyst.
authors.affiliation: Division of Oral and Maxillofacial Pathology, Department of Pathology, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Angela C
authors.initials: AC
authors.lastname: Chi
authors.forename: James R
authors.initials: JR
authors.lastname: Owings
authors.forename: Susan
authors.initials: S
authors.lastname: Muller
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016301:Alveolar Bone Loss / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D005882:Gingival Diseases / Q000473:pathology*; D006801:Humans; D008336:Mandibular Diseases / Q000473:pathology; D008439:Maxillary Diseases / Q000473:pathology; D008875:Middle Aged; D009807:Odontogenic Cysts / Q000473:pathology*