Recurrent acute interstitial nephritis induced by azithromycin.
A 14-year-old girl is reported with recurrent, azithromycin-induced, acute interstitial nephritis. The second episode was more severe than the first; and although both were treated with intensive corticosteroid therapy, renal function remained impaired. Although most cases of antibiotic induced acute interstitial nephritis are benign and self-limited, some patients are at risk for permanent renal injury.
Soni
Neha
N
Department of Pediatrics, Division of Pediatric Nephrology, Westchester Medical Center/New York Medical College, Valhalla, NY 10595, USA.
Harrington
John W
JW
Weiss
Robert
R
Chander
Praveen
P
Vyas
Shefali
S
D000208:Acute Disease; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D017963:Azithromycin / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D012008:Recurrence
D000900:Anti-Bacterial Agents; D005938:Glucocorticoids; D017963:Azithromycin; D011241:Prednisone; D008775:Methylprednisolone