title: Oropharyngeal carriage and penicillin resistance of Neisseria meningitidis in primary school children in Manisa, Turkey.
abstract: BACKGROUND
  To determine the oropharyngeal carriage rates and serogroups of Neisseria meningitidis in primary school children in Manisa, Turkey as well as the prevalence and penicillin resistance of N. meningitidis.
  
  
  METHODS
  Throat swabs obtained from 1128 children were cultured and recovered organisms were tested by disk diffusion method and the E-test for antimicrobial susceptibilities.
  
  
  RESULTS
  The carriage rate of N. meningitidis in our region was 6.2% (71 strains) and the serogroups identified were serogroups A (28.1%), B (22.5%), C (35.2%), D (2.8%) and W-135 (11.2%). Penicillin resistance was found in 16 strains (22.5%), while beta-lactamase activity was found in none.
  
  
  CONCLUSIONS
  The carriage rate of N. meningitidis and serogroups are similar to the rates reported in other countries. Continued surveillance of meningococci for antimicrobial resistance will allow early detection of changes in susceptibility patterns that might affect recommendations for chemoprophylaxis as well as for treatment.
authors.affiliation: Celal Bayar University Medicine Faculty, Department of Microbiology and Clinical Microbiology, Turkey. horugazi@hotmail.com
authors.forename: H
authors.initials: H
authors.lastname: Gazi
authors.forename: S
authors.initials: S
authors.lastname: Surucuoglu
authors.forename: B
authors.initials: B
authors.lastname: Ozbakkaloglu
authors.forename: S
authors.initials: S
authors.lastname: Akcali
authors.forename: N
authors.initials: N
authors.lastname: Ozkutuk
authors.forename: K
authors.initials: K
authors.lastname: Degerli
authors.forename: S
authors.initials: S
authors.lastname: Kurutepe
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009345:Neisseria meningitidis / Q000187:drug effects* / Q000302:isolation & purification*; D009960:Oropharynx / Q000382:microbiology*; D010403:Penicillin Resistance; D014421:Turkey