The association between obesity and the progression of prostate and renal cell carcinoma.
Obesity has been linked to the incidence and mortality of several malignancies, including prostate and renal cancer. Increased body mass appears to have a more consistent association with prostate cancer mortality than incidence and recent studies suggest that it may be related to higher recurrence rates after radical prostatectomy. Obesity has an even stronger association with the development and progression of renal cancer, particularly in women. Since obesity is one of few modifiable risk factors that may impact the clinical course of these cancers, lifestyle and dietary changes to limit obesity should be recommended.
Amling
Christopher L
CL
Department of Urology, Naval Medical Center, 34800 Bob Wilson Drive, San Diego, CA 92134-5000, USA. clamling@nmcsd.med.navy.nil
D002292:Carcinoma, Renal Cell / Q000150:complications* / Q000401:mortality; D004038:Diet, Reducing; D018450:Disease Progression; D005260:Female; D015438:Health Behavior; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications* / Q000401:mortality; D008019:Life Style; D008297:Male; D009765:Obesity / Q000150:complications* / Q000628:therapy; D011468:Prostatectomy / Q000401:mortality; D011471:Prostatic Neoplasms / Q000150:complications* / Q000401:mortality / Q000601:surgery