Borate transport and cell growth and proliferation. Not only in plants.
Boron is an abundant mineral essential for the life cycle of plants and may play a role in animal development and growth. Very little is known about boron homeostasis in plant and animal cells and the physiological roles of boron in animals. The recent identification of boron transporters, BOR1 in plants and NaBC1 in mammals, and that NaBC1 functions as an electrogenic Na+-coupled borate transporter essential for cell growth and proliferation open the way to probe the roles of boron in cellular function and physiology.
Park
Meeyoung
M
Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA.
Li
Qin
Q
Shcheynikov
Nikolay
N
Muallem
Shmuel
S
Zeng
Weizong
W
D000818:Animals; D001693:Biological Transport, Active; D001881:Borates / Q000378:metabolism*; D001895:Boron / Q000502:physiology*; D002453:Cell Cycle / Q000502:physiology; D048708:Cell Growth Processes / Q000502:physiology*; D049109:Cell Proliferation; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D009363:Neoplasm Proteins / Q000502:physiology; D059828:Plant Cells; D010944:Plants / Q000378:metabolism
C113699:BCAS1 protein, human; D001881:Borates; D009363:Neoplasm Proteins; D001895:Boron