title: RETRACTED: Darwinian selection on a selfing locus.
abstract: The shift to self-pollination is one of the most prevalent evolutionary transitions in flowering plants. In the selfing plant Arabidopsis thaliana, pseudogenes at the SCR and SRK self-incompatibility loci are believed to underlie the evolution of self-fertilization. Positive directional selection has driven the evolutionary fixation of pseudogene alleles of SCR, leading to substantially reduced nucleotide variation. Coalescent simulations indicate that this adaptive event may have occurred very recently and is possibly associated with the post-Pleistocene expansion of A. thaliana from glacial refugia. This suggests that ancillary morphological innovations associated with self-pollination can evolve rapidly after the inactivation of the self-incompatibility response.
authors.affiliation: Department of Genetics, North Carolina State University, Box 7614, Raleigh, NC 27695, USA.
authors.forename: Kentaro K
authors.initials: KK
authors.lastname: Shimizu
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: Cork
authors.forename: Ana L
authors.initials: AL
authors.lastname: Caicedo
authors.forename: Charlotte A
authors.initials: CA
authors.lastname: Mays
authors.forename: Richard C
authors.initials: RC
authors.lastname: Moore
authors.forename: Kenneth M
authors.initials: KM
authors.lastname: Olsen
authors.forename: Stephanie
authors.initials: S
authors.lastname: Ruzsa
authors.forename: Graham
authors.initials: G
authors.lastname: Coop
authors.forename: Carlos D
authors.initials: CD
authors.lastname: Bustamante
authors.forename: Philip
authors.initials: P
authors.lastname: Awadalla
authors.forename: Michael D
authors.initials: MD
authors.lastname: Purugganan
mesh_terms: D000483:Alleles; D017360:Arabidopsis / Q000235:genetics* / Q000502:physiology*; D005075:Biological Evolution; D002874:Chromosome Mapping; D002980:Climate; D021901:DNA, Intergenic; D017343:Genes, Plant; D014644:Genetic Variation; D018745:Genome, Plant; D005843:Geography; D006239:Haplotypes; D016013:Likelihood Functions; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D010802:Phylogeny; D010940:Plant Proteins; D011058:Pollen; D011110:Polymorphism, Genetic; D020641:Polymorphism, Single Nucleotide; D011494:Protein Kinases / Q000235:genetics* / Q000502:physiology; D011544:Pseudogenes; D011995:Recombination, Genetic; D012641:Selection, Genetic; D013995:Time
chemical_list: D021901:DNA, Intergenic; D010940:Plant Proteins; D011494:Protein Kinases; C079832:S-receptor kinase