title: [Xerostomia. Diagnosis and treatment].
abstract: Comprehensive examination and treatment were made of 57 patients with xerostomia on the background of different salivary glands diseases. Mexidol was used for treatment in the form of external blockade in the region of the salivary glands. Expressed clinical effect was observed in 67% of patients with considerable reduction or disappearance of oral cavity xerostomia, decrease of glands swelling and general condition improvement. Indices of lipid peroxidation and of antioxidant protection of mixed saliva of xerostomic patients differed from analogous control data and depended upon the type of xerostomia involved.
authors.forename: V V
authors.initials: VV
authors.lastname: Afanas'ev
authors.forename: A A
authors.initials: AA
authors.lastname: Irmiiaev
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000975:Antioxidants / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D010847:Picolines / Q000494:pharmacology / Q000627:therapeutic use*; D012463:Saliva / Q000737:chemistry / Q000187:drug effects; D012796:Sialography; D016896:Treatment Outcome; D014987:Xerostomia / Q000175:diagnosis / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D000975:Antioxidants; D010847:Picolines; C070020:emoxypine succinate