Splitting hairs--discovery of a new DNA repair and transcription factor for the human disease trichothiodystrophy.
The gene responsible for the TTD-A group of the DNA repair deficient disease trichothiodystrophy has been identified as a small, 8 kDa, component of the transcription factor TFIIH which contributes to the stability and concentration of TFIIH in vivo.
Cleaver
James E
JE
Auerback Melanoma Laboratory, Room N431, UCSF Cancer Center, University of California, Box 0808, San Francisco, CA 94143-0808, USA. jcleaver@cc.ucsf.edu
D004260:DNA Repair; D006201:Hair Diseases / Q000235:genetics*; D006801:Humans; D051758:Transcription Factor TFIIH; D019473:Transcription Factors, TFII / Q000502:physiology*; D014158:Transcription, Genetic
D019473:Transcription Factors, TFII; D051758:Transcription Factor TFIIH