title: Participation of endogenous corticosteroids in inflammatory response in type 2 streptozotocin diabetic rats.
abstract: The inflammatory response is decreased in diabetic animals. After adrenals removal this impaired response in type 2 diabetic rats evaluated by pleurisy and vascular permeability tests was restored. Our studies demonstrate that endogenous corticosteroids play a partial role in the impaired inflammatory response in type 2 streptozotocin diabetic rats.
authors.affiliation: Paranaense University, 87502-210 Umuarama, PR, Brazil.
authors.forename: G A N
authors.initials: GA
authors.lastname: de Melo
authors.forename: J L
authors.initials: JL
authors.lastname: Sartoretto
authors.forename: S M
authors.initials: SM
authors.lastname: Caparroz-Assef
authors.forename: C A
authors.initials: CA
authors.lastname: Bersani-Amado
authors.forename: Z B
authors.initials: ZB
authors.lastname: Fortes
authors.forename: R K N
authors.initials: RK
authors.lastname: Cuman
mesh_terms: D000305:Adrenal Cortex Hormones / Q000502:physiology*; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism* / Q000473:pathology*; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism* / Q000473:pathology*; D018836:Inflammation Mediators / Q000502:physiology*; D008297:Male; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000305:Adrenal Cortex Hormones; D018836:Inflammation Mediators