Dielectric modulation of biological water.
We show that water constrained by vicinal hydrophobes undergoes a librational dynamics that lowers the dielectric susceptibility and induces a "redshift" of the relaxation frequency in the hydration shell. The results shed light on the way proteins enhance their intramolecular interactions as they fold or associate.
Despa
Florin
F
Department of Chemistry, The University of Chicago, Chicago, Illinois 60637, USA.
Fernández
Ariel
A
Berry
R Stephen
RS
D001834:Body Water / Q000737:chemistry*; D003198:Computer Simulation; D004553:Electric Conductivity; D008956:Models, Chemical; D008958:Models, Molecular; D008968:Molecular Conformation; D011487:Protein Conformation; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry*; D055672:Static Electricity; D014867:Water / Q000737:chemistry*
D011506:Proteins; D014867:Water