[Brain MR perfusion and MR spectroscopy in differentiation of radiation necrosis from tumor recurrence (case report)].
It is not always possible to differentiate tumor recurrence from radiation necrosis using conventional MR images. In this report we present a case of pathologically proven radiation necrosis which appeared as nodular contrast enhancement on conventional MR images in a patient who was surgically treated for grade II astrocytoma 5 years ago. There were decreased choline, creatine and N-acetyl aspartate peaks and significantly increased lipid peak on multivoxel H1-MR spectroscopy while there was no significant perfusion increase on MR perfusion. These findings suggested changes secondary to radiation necrosis.
Tekşam
Mehmet
M
Başkent Universitesi Tip Fakültesi, Radyoloji Anabilim Dali, Ankara, Turkey.
Kayahan
Esra Meltem
EM
Yerli
Hasan
H
Ağildere
A Muhteşem
AM
D001254:Astrocytoma / Q000473:pathology*; D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D011832:Radiation Injuries / Q000473:pathology*