title: Changes of plasma coenzyme Q10 levels in early infancy.
abstract: Rapid perfusion of oxygen in infants at birth may increase oxidative stress which has been incriminated in serious diseases including neonatal respiratory distress syndrome, chronic lung disease, and retinopathy of prematurity. Elucidating the antioxidant defense systems of neonates in clinical practice is important. Coenzyme Q(10) is a widely distributed, redox-active quinoid compound originally discovered as an essential part of the mitochondrial respiratory chain in mammals. Although coenzyme Q(10) is a powerful lipid antioxidant in vivo, few data pertain to plasma CoQ(10) levels in infants. This is the first paper to report plasma coenzyme Q(10) levels in preterm infants.
authors.affiliation: Department of Pediatrics, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
authors.forename: Shuko
authors.initials: S
authors.lastname: Sato
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Tsukahara
authors.forename: Yusei
authors.initials: Y
authors.lastname: Ohshima
authors.forename: Naoko
authors.initials: N
authors.lastname: Ohta
authors.forename: Mayumi
authors.initials: M
authors.lastname: Uchiyama
authors.forename: Kyouichi
authors.initials: K
authors.lastname: Sekine
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Uetake
authors.forename: Mitsufumi
authors.initials: M
authors.lastname: Mayumi
mesh_terms: D000975:Antioxidants / Q000737:chemistry; D003067:Coenzymes; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D008055:Lipids / Q000737:chemistry; D010084:Oxidation-Reduction; D018384:Oxidative Stress; D010100:Oxygen / Q000378:metabolism; D010477:Perfusion; D013997:Time Factors; D014451:Ubiquinone / Q000031:analogs & derivatives* / Q000097:blood*; D014810:Vitamin E / Q000737:chemistry
chemical_list: D000975:Antioxidants; D003067:Coenzymes; D008055:Lipids; D014451:Ubiquinone; D014810:Vitamin E; C024989:coenzyme Q10; D010100:Oxygen