Construction of a protein array on amyloid-like fibrils using co-assembly of designed peptides.
Amyloid-like fibrils formed from de novo designed short peptides, made up a nanoscale scaffold on which streptavidin was arranged in a regular spacing, potentially allowing the development into an array technology utilizing bio-nanoconstructs.
Kodama
Hiroyuki
H
Department of Bioengineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259-B-40 Nagatsuta-cho, Midori-ku, Yokohama 226-8501, Japan.
Matsumura
Sachiko
S
Yamashita
Taro
T
Mihara
Hisakazu
H
D000595:Amino Acid Sequence; D000682:Amyloid / Q000737:chemistry* / Q000378:metabolism* / Q000648:ultrastructure; D046529:Microscopy, Electron, Transmission; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism*; D040081:Protein Array Analysis / Q000295:instrumentation / Q000379:methods*
D000682:Amyloid; D010455:Peptides