title: [Uncorrected transposition of the great arteries and large ventricular septum defect perioperative management of a caesarean section].
abstract: Patients with congenital cyanotic heart disease are a challenge to the anaesthetist due to the individual haemodynamic characteristics. Maintaining a balance between systemic and pulmonary-vascular resistance is crucial. Here we outline the successful perioperative management of a 24-year-old female with uncorrected transposition of the great arteries (D-TGA) and large septal defect of the ventricle (functionally single ventricle). She was transferred to our perinatologic centre in the 32nd week of pregnancy with symptoms of increasing cardial insufficiency. The peripartum management was agreed upon at an interdisciplinary conference and caesarean section was performed in the 35th week of pregnancy with epidural anaesthesia and no significant problems. Due to hypercoagulability and the risk of "paradoxical" embolism, low molecular weight heparin was given for 6 weeks post partum. The infant was underweight and was admitted to the neonatal intensive care unit, where she made a satisfactory progress.
authors.affiliation: Klinik für Anästhesiologie und Intensivtherapie, Friedrich-Schiller-Universität, Jena. cwsm.schummer@gmx.de
authors.forename: W
authors.initials: W
authors.lastname: Schummer
authors.forename: C
authors.initials: C
authors.lastname: Schummer
authors.forename: E
authors.initials: E
authors.lastname: Schleussner
authors.forename: R
authors.initials: R
authors.lastname: Fröber
authors.forename: M
authors.initials: M
authors.lastname: Ferrari
authors.forename: J
authors.initials: J
authors.lastname: Fuchs
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D002585:Cesarean Section; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000150:complications* / Q000473:pathology; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D011182:Postoperative Care; D011247:Pregnancy; D014188:Transposition of Great Vessels / Q000150:complications* / Q000473:pathology
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight