HESAS: HERVs Expression and Structure Analysis System.
CONCLUSIONS
HESAS (HERVs Expression and Structure Analysis System) database was developed to understand the human endogenous retroviruses (HERVs) that have an effect on the expression of human functional genes. The database products are generated by the exon-based expressed sequence tag clustering and reconstructing of partial HERV structures that result from various mutations during primate evolution. The expression types were classified according to the existence of splicing, transcriptional start and polyadenylation signal sites. The database currently contains HERV information on 26,981 human genes of exon-intron structure. The HERV elements were inserted into 17,317 of these genes and linked to expression with 898 genes.


BACKGROUND
http://www.primate.or.kr/HESAS CONTACT: khs307@pusan.ac.kr.
Kim
Tae-Hyung
TH
PBBRC, Interdisciplinary Research Program of Bioinformatics, College of Natural Sciences, Pusan National University, Busan 609-735, Korea.
Jeon
Yeo-Jin
YJ
Kim
Woo-Yeon
WY
Kim
Heui-Soo
HS
D000465:Algorithms; D002874:Chromosome Mapping / Q000379:methods*; D003628:Database Management Systems; D030561:Databases, Nucleic Acid; D020077:Endogenous Retroviruses / Q000235:genetics*; D020224:Expressed Sequence Tags; D015894:Genome, Human; D006801:Humans; D016247:Information Storage and Retrieval / Q000379:methods*; D016415:Sequence Alignment / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software