title: A rare cause of complete heart block after transdermal botanical treatment for psoriasis.
abstract: We report the case of a 59-year-old man with a new 3 degrees AV block with a history of psoriasis. After implantation of a definitive DDDR pacemaker, the patient reported a transdermal self-medication with an extract of Nerium oleander for the treatment of his psoriasis. The pharmacological, epidemiological, and clinical features are discussed in brief.
authors.affiliation: Kantonsspital Glarus, Department of Internal Medicine, Glarus, Switzerland.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Wojtyna
authors.forename: Frank
authors.initials: F
authors.lastname: Enseleit
mesh_terms: D000279:Administration, Cutaneous; D002037:Bundle-Branch Block / Q000139:chemically induced* / Q000175:diagnosis; D002298:Cardenolides / Q000008:administration & dosage / Q000633:toxicity*; D003937:Diagnosis, Differential; D004562:Electrocardiography / Q000187:drug effects; D006327:Heart Block / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D030007:Nerium / Q000633:toxicity*; D008517:Phytotherapy / Q000009:adverse effects*; D010936:Plant Extracts / Q000008:administration & dosage / Q000633:toxicity*; D011565:Psoriasis / Q000188:drug therapy*
chemical_list: D002298:Cardenolides; D010936:Plant Extracts; C021065:oleandrin