[Recurrent malignant tumors of the adrenal glands: treatment and prognosis].
The malignant adrenal tumors (MAT) have aggressive trend and inclined to often recurrences and early metastasis. The author has analyzed the causes of the recurrences of MAT in 292 patients which have been treated in the clinic. The recurrences of MAT were shown to originate rather from adrenal cortex than from adrenal medulla. The anaplastic and low-grade differentiated cancers associate with the worst prognosis and low efficacy of treatment. Regional lymphatic collectors were the most often observed localization of the recurrent tumor (63.5%). The development of new surgical procedures which include prophylactic systematic cellular retroperitoneal dissection will decrease the number of MAT recurrences after the primary surgical operation. The tumor recurrence is a bad prognostic factor. The patients (55.8%) with MAT recurrence were diagnosed to have their tumor incurable.
Kvacheniuk
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D000305:Adrenal Cortex Hormones / Q000378:metabolism; D000310:Adrenal Gland Neoplasms / Q000378:metabolism / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D000315:Adrenalectomy; D005260:Female; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000378:metabolism / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D009376:Neoplasms, Hormone-Dependent / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D011379:Prognosis
D000305:Adrenal Cortex Hormones