Anti-fungal sesquiterpenoid from the root exudate of Solanum abutiloides.
The Solanum abutiloides plant is highly resistant to soil-borne pathogens such as Fusarium oxysporum f. sp. melongenae, Verticillium dahliae, and Ralstonia solanacearum. This species is utilized as a mating source of resistant cultivars and is also used as a rootstock. The root exudate of Solanum abutiloides was extracted from a soil system composed of charcoal and vermiculite. Anti-fungal activity was found in the extract, and an active ingredient was isolated. The chemical structure of the active compound was determined to be 3-beta-acetoxysolavetivone, a new sesquiterpenoid. The anti-fungal activity of 3-beta-acetoxysolavetivone examined by the inhibition of spore germination of Fusarium oxysporum was close to that of lubimin, and higher than that of solavetivone.
Yokose
Toshiyuki
T
Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University, Sapporo 060-8589, Japan.
Katamoto
Kozue
K
Park
Sun
S
Matsuura
Hideyuki
H
Yoshihara
Teruhiko
T
D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005670:Fusarium / Q000187:drug effects; D015394:Molecular Structure; D010936:Plant Extracts; D018517:Plant Roots / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D012987:Soil; D032322:Solanum / Q000737:chemistry*; D013172:Spores, Fungal / Q000187:drug effects; D013141:Spiro Compounds; D000094162:Phytoalexins
D000935:Antifungal Agents; D005663:Furans; D010936:Plant Extracts; D012717:Sesquiterpenes; D012987:Soil; C438421:solavetivone; D013141:Spiro Compounds; D000094162:Phytoalexins