title: Formates and dithionates: sensitive EPR-dosimeter materials for radiation therapy.
abstract: Polycrystalline formates and dithionates are promising materials for EPR dosimetry, as large yields of radiation induced stable radicals are formed with a linear dose response. Rapid spin relaxation rates were detected in many of the substances, indicating that a high microwave power can be applied during EPR acquisition in order to improve sensitivity. Different techniques used to further improve the sensitivity, such as the replacement of 7Li with 6Li or exchange of protons with deuterons in the corresponding crystalline matrices and metal ion doping are discussed. It is concluded that formates and dithionates may be up to 10 times as sensitive as L-alpha-alanine.
authors.affiliation: Department of Medicine and Care, Radiation Physics, Faculty of Health Sciences, University of Linköping, S-581 85 Linköping, Sweden. eva.lund@imv.liu.se
authors.forename: E
authors.initials: E
authors.lastname: Lund
authors.forename: H
authors.initials: H
authors.lastname: Gustafsson
authors.forename: M
authors.initials: M
authors.lastname: Danilczuk
authors.forename: M D
authors.initials: MD
authors.lastname: Sastry
authors.forename: A
authors.initials: A
authors.lastname: Lund
authors.forename: T A
authors.initials: TA
authors.lastname: Vestad
authors.forename: E
authors.initials: E
authors.lastname: Malinen
authors.forename: E O
authors.initials: EO
authors.lastname: Hole
authors.forename: E
authors.initials: E
authors.lastname: Sagstuen
mesh_terms: D004307:Dose-Response Relationship, Radiation; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods*; D005561:Formates / Q000737:chemistry* / Q000528:radiation effects*; D008872:Microwaves; D011874:Radiometry / Q000295:instrumentation / Q000379:methods*; D011878:Radiotherapy / Q000379:methods*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013871:Thiones / Q000737:chemistry* / Q000528:radiation effects*
chemical_list: D005561:Formates; D013871:Thiones; C030544:formic acid