An experimental infection (II) to investigate the importance of indirect classical swine fever virus transmission by excretions and secretions of infected weaner pigs.
An experiment was set up to investigate the role of excretions and secretions in the indirect transmission of classical swine fever virus (CSFV). In five small pens, 10 weaner pigs (two pigs per pen) were housed and inoculated with CSFV. Experimental infection was successful in all pigs. The infected pigs were kept in the pens for a period of 15 days after which the pens were depopulated and pigs were killed. At the moment of depopulation, all inoculated pigs were visibly clinically diseased and had high fever. Ten hours later the same pens were repopulated with five pairs of susceptible pigs. From inoculation onwards and especially between depopulation and restocking, the pens were neither cleaned nor disinfected. Four days post-repopulation, three of the susceptible pigs were detected positive on virus isolation. A fourth pig was detected positive 2 days later. Later on, the remaining pigs also became infected, most probably due to contact and between pen infections. It can be concluded that transmission of the virus via excretions and secretions succeeded in four of 10 pigs. This result indicates that transmission of CSFV via excretions and secretions can be of importance in a late, clinical stage of disease.
Ribbens
S
S
Department of Reproduction, Obstetrics and Herd Health, Faculty of Veterinary Medicine, Unit of Veterinary Epidemiology, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium. stefaan.ribbens@ugent.be
Dewulf
J
J
Koenen
F
F
Laevens
H
H
Mintiens
K
K
de Kruif
A
A
D000818:Animals; D000831:Animals, Newborn; D006691:Classical Swine Fever / Q000097:blood / Q000635:transmission*; D006692:Classical Swine Fever Virus / Q000472:pathogenicity*; D018562:Disease Transmission, Infectious / Q000662:veterinary*; D005243:Feces / Q000821:virology; D006799:Housing, Animal; D012463:Saliva / Q000821:virology; D013552:Swine; D016896:Treatment Outcome; D014886:Weaning