Isochromosome 20p associated with multiple congenital abnormalities.
A second case of tetrasomy 20p due to an additional isochromosome 20p is reported. This resulted in a spontaneous intrauterine death with multiple congenital abnormalities. In keeping with the previous report, the foetus had poor ossification resulting in multiple long bone fractures.
Fryer
Alan E
AE
Departments of Clinical Genetics Pathology Radiology, Royal Liverpool Children's Hospital Department of Obstetrics, Countess of Chester Hospital Department of Cytogenetics, Liverpool Women's Hospital.
Ashworth
Michael
M
Hawe
Jed
J
Pilling
David
D
Pauling
Margaret
M
Maye
Una
U
D002869:Chromosome Aberrations; D002890:Chromosomes, Human, Pair 20; D005260:Female; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D011256:Pregnancy Outcome