title: Serum leptin elevation in obese women with PCOs: a continuing controversy.
abstract: OBJECTIVE
  To evaluate leptin levels in a sample of obese women with PCOS and compare the results with obese and non-obese control, to be ultimately correlated with BMI, and insulin sensitivity.
  
  
  METHODS
  Leptin and insulin assays by immuno-radiometric method, glucose assay by enzymatic colorimetric method.
  
  
  RESULTS
  Leptin levels were significantly different between obese and non-obese subjects, and were significantly different between insulin resistant and non-insulin resistant obese PCOS, but were not significantly different between obese non-insulin resistant PCOS, and obese controls.
  
  
  CONCLUSIONS
  Body mass index and insulin resistance are the two main factors governing serum leptin levels.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University, Alexandria, Egypt. hishamsaleh@link.net
authors.forename: Hisham Ali
authors.initials: HA
authors.lastname: Saleh
authors.forename: Mohamed Amr
authors.initials: MA
authors.lastname: El-Nwaem
authors.forename: Magdy Mamdouh
authors.initials: MM
authors.lastname: El-Bordiny
authors.forename: Hala Mohamed El-Sayed
authors.initials: HM
authors.lastname: Maqlad
authors.forename: Amr Ahmed
authors.initials: AA
authors.lastname: El-Mohandes
authors.forename: Ebtehag Mohamed
authors.initials: EM
authors.lastname: Eldaqaq
mesh_terms: D000328:Adult; D015992:Body Mass Index; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000097:blood*; D007328:Insulin / Q000097:blood*; D007333:Insulin Resistance; D020738:Leptin / Q000097:blood*; D009765:Obesity / Q000150:complications*; D011085:Polycystic Ovary Syndrome / Q000150:complications*
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin; D020738:Leptin