title: Towards enantioselective nucleophilic trifluoromethylation.
abstract: Various trifluoroacetamides and trifluoromethanesulfinamides, derived from chiral silylated amino alcohols, have been synthesized with the goal of achieving enantioselective nucleophilic trifluoromethylation. The best results were obtained with (R)-phenylglycinol derivatives, but the ee values did not exceed 30 %.
authors.affiliation: Laboratoire SERCOF (UMR CNRS 5181), Université Claude Bernard-Lyon 1, Bât. Chevreul, 43, Bd du 11 novembre 1918, 69622 Villeurbanne, France.
authors.forename: Solveig
authors.initials: S
authors.lastname: Roussel
authors.forename: Thierry
authors.initials: T
authors.lastname: Billard
authors.forename: Bernard R
authors.initials: BR
authors.lastname: Langlois
authors.forename: Laurent
authors.initials: L
authors.lastname: Saint-James