[Primary analysis of the situation of hepatitis G virus infection in different groups of people].
In order to investigate the situation of hepatitis G virus (HGV) infection among different groups of people, two self-selected peptides from HGV NS5 were used to develop an indirect ELISA for anti-HGV IgG detection. 1209 sera from different peoples were detected and the positive rate of anti-HGV IgG was (3.8%). Among these groups the group of non A-E hepatitis had the highest anti-HGV positive rate (20.5%), higher than that in the groups of natural people (0.8%) and other hepatitis patients (3.3%), the difference was significant. The anti-HGV IgG positive rate in the group of HC patients 8.0% was higher than that in other hepatitis A-E patients, the positive rate (8.0%) in paid donors was higher than that in voluntary donors (0%), and that in groups with venereal diseases and HIV infection were 3.6% and 8.0%, respectively. The results suggested that there has higher rate of HGV infection in our country; HGV is the important factor causing non A-E, the paid donors is the dangerous group, they should be strictly screened, and the people with transfusion have higher rate of HGV infection. Since there is different rate of HGV infection in different human population so it is important to study further the epidemiological characteristics of HGV for its prevention.
He
H
H
Dept. of Virology, 302 Hospital, Beijing 100039.
Mao
P
P
Han
J
J
Bai
Y
Y
Ju
L
L
Zhu
L
L
Hong
S
S
D002681:China / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D018178:Flaviviridae Infections / Q000453:epidemiology* / Q000276:immunology / Q000821:virology; D029407:GB virus C / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000097:blood; D006525:Hepatitis, Viral, Human / Q000453:epidemiology* / Q000276:immunology / Q000821:virology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood
D006508:Hepatitis Antibodies; D007074:Immunoglobulin G