title: Effect on pKa of metal-bound water molecules in lanthanide ion-induced cyclen "cavities".
abstract: [reaction: see text] The macrocyclic cyclen conjugates 1-4 were synthesized with the aim of forming lanthanide ion-based macrocyclic conjugates possessing deep cavities, formed upon complexation to various lanthanide ions. These complexes all possess metal-bound water molecules, where the pKa of the water molecules depends on the nature of the cavity.
authors.affiliation: Department of Chemistry, Trinity College Dublin, Dublin 2, Ireland. gunnlaut@tcd.ie
authors.forename: Thorfinnur
authors.initials: T
authors.lastname: Gunnlaugsson
authors.forename: Dermot F
authors.initials: DF
authors.lastname: Brougham
authors.forename: Ann-Marie
authors.initials: AM
authors.lastname: Fanning
authors.forename: Mark
authors.initials: M
authors.lastname: Nieuwenhuyzen
authors.forename: John E
authors.initials: JE
authors.lastname: O'Brien
authors.forename: Romain
authors.initials: R
authors.lastname: Viguier