title: Strong modulation of two-photon excited fluorescence of quadripolar dyes by (de)protonation.
abstract: Two quadripolar dyes have been designed and synthesized that present large cross sections for two-photon excitation and whose fluorescence responds strongly to (de)protonation. These dyes are considered as prototypes of molecular pH probes for multiphoton fluorescence microscopy.
authors.affiliation: Synthèse et Electrosynthèse Organiques (CNRS UMR 6510), Institut de Chimie, Université de Rennes 1, Campus de Beaulieu, Bâtiment 10A, F-35042 Rennes Cedex, France.
authors.forename: Martinus H V
authors.initials: MH
authors.lastname: Werts
authors.forename: Said
authors.initials: S
authors.lastname: Gmouh
authors.forename: Olivier
authors.initials: O
authors.lastname: Mongin
authors.forename: Thomas
authors.initials: T
authors.lastname: Pons
authors.forename: Mireille
authors.initials: M
authors.lastname: Blanchard-Desce
mesh_terms: D001555:Benzene Derivatives / Q000138:chemical synthesis / Q000737:chemistry; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D008567:Membranes, Artificial; D036641:Microscopy, Fluorescence, Multiphoton / Q000379:methods*; D010713:Phosphatidylcholines / Q000737:chemistry; D010777:Photochemistry; D017785:Photons; D011522:Protons; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet
chemical_list: D001555:Benzene Derivatives; D005456:Fluorescent Dyes; D008567:Membranes, Artificial; D010713:Phosphatidylcholines; D011522:Protons; C017251:1,2-oleoylphosphatidylcholine