title: Would Sacaca, Croton cajucara Benth (Euphorbiaceae) be an hepatotoxic plant like Germander, Teucrium chamaedrys L. (Labiatae)?
abstract: Clinical and experimental studies have consistently incriminated the medicinal plant germander (Teucrium chamaedrys L.) in epidemic and sporadic cases of liver diseases. The sacaca (Croton cajucara Benth), a common plant in Brazilian Amazon region also comes being incriminated in similar clinical cases. Of both plants were isolated diterpenoid compounds with similar chemical structures.
authors.affiliation: Instituto Evandro Chagas da Secretaria de Vigilância em Saúde do Ministério da saúde. msoares@iec.pa.gov.br
authors.forename: Manoel do Carmo Pereira
authors.initials: Mdo C
authors.lastname: Soares
mesh_terms: D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D029802:Croton / Q000737:chemistry / Q000633:toxicity*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D006801:Humans; D031367:Teucrium / Q000737:chemistry / Q000633:toxicity*
chemical_list: D004224:Diterpenes