title: Osseous lesions of the pelvis and long tubular bones containing both fat and fluid-like signal intensity: an analysis of 28 patients.
abstract: OBJECTIVE
  The purpose of this study was to explore the nature of lesions in the pelvis and the long tubular bones that, with MR imaging, were found to contain both fat and fluid-like signal intensity and to correlate these findings with those of radiography, histologic analysis, and clinical and radiographic follow-up.
  
  
  METHODS
  A retrospective review of the radiologic, clinical and histologic parameters of 28 patients with lesions in the pelvis and long tubular bones comprised of elements that demonstrated both fat and fluid signal intensity characteristics by MR imaging was performed. Several parameters were analyzed. Histologic analysis was available in 12 patients. Clinical and, or imaging follow-up was available in 13 patients.
  
  
  RESULTS
  Imaging and histologic findings suggested the presence of fat and fluid and fluid components in all lesions with which could be divided into distinct MR imaging patterns. Histologic analysis suggested the possibility of a shared pathogenesis among several different lesions.
  
  
  CONCLUSIONS
  All lesions of the long tubular bones in our series revealing both fat and fluid-like signal intensities with MR imaging were nonaggressive on the basis of other imaging findings, follow-up assessment, histologic analysis, or combinations of the three. Histologic findings suggest a relationship among lipomas, fat necrosis and cystic infarct of bone.
authors.affiliation: Department of Radiology, VA Healthcare System, 3350 La Jolla Village Dr., La Jolla, CA 92161, USA. cbchung@ucsd.edu
authors.forename: Christine B
authors.initials: CB
authors.lastname: Chung
authors.forename: Mark
authors.initials: M
authors.lastname: Murphey
authors.forename: Gina
authors.initials: G
authors.lastname: Cho
authors.forename: Mark
authors.initials: M
authors.lastname: Schweitzer
authors.forename: Jeurg
authors.initials: J
authors.lastname: Hodler
authors.forename: Parvis
authors.initials: P
authors.lastname: Haghihi
authors.forename: Donald
authors.initials: D
authors.lastname: Resnick
mesh_terms: D000273:Adipose Tissue / Q000473:pathology; D000293:Adolescent; D000328:Adult; D000368:Aged; D001845:Bone Cysts / Q000175:diagnosis / Q000473:pathology; D001847:Bone Diseases / Q000175:diagnosis* / Q000473:pathology; D001859:Bone Neoplasms / Q000175:diagnosis / Q000473:pathology; D005122:Exudates and Transudates; D005218:Fat Necrosis / Q000175:diagnosis / Q000473:pathology; D005260:Female; D005269:Femur / Q000098:blood supply / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D006811:Humerus / Q000098:blood supply / Q000473:pathology; D007085:Ilium / Q000098:blood supply / Q000473:pathology; D007238:Infarction / Q000175:diagnosis / Q000473:pathology; D008067:Lipoma / Q000175:diagnosis / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010384:Pelvic Bones / Q000098:blood supply / Q000473:pathology*; D015642:Radiology, Interventional; D012189:Retrospective Studies; D013977:Tibia / Q000098:blood supply / Q000473:pathology