Neuroblastoma update.
OBJECTIVE
The purpose of this paper is to review the most recent medical literature pertaining to neuroblastoma. Clinically, progress continues to be made on the refinement of radiographic staging and risk stratification-based treatment.


RESULTS
Meanwhile, experimental efforts focus on the continued search for biologic prognostic markers and the development of novel therapies including second-generation retinoids, tumor vaccines, and new modes of drug delivery with improved safety and efficacy.


CONCLUSIONS
Review of the recent neuroblastoma literature demonstrates continued progress in our ability to understand and treat this enigmatic tumor.
Henry
Marion C W
MC
Section of Pediatric Surgery, Yale University School of Medicine, New Haven, CT 06520-8062, USA.
Tashjian
David B
DB
Breuer
Christopher K
CK
D014408:Biomarkers, Tumor / Q000032:analysis*; D006801:Humans; D009367:Neoplasm Staging / Q000379:methods*; D009447:Neuroblastoma / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D011379:Prognosis; D018570:Risk Assessment
D014408:Biomarkers, Tumor