[Determination of entrapment efficiency of breviscapine nanoliposomes].
OBJECTIVE
To determine the entrapment efficiency of breviscapine nanoliposomes.


METHODS
Retrodialysis method was used to determine the entrapment efficiency of breviscapine nanoliposomes. The drug recovery and the sample recovery were considered to verify the feasibility of the method.


RESULTS
The drug recovery was (99.6 +/- 0.6)%. The sample recovery was (99.9 +/- 0.8)%. The entrapment efficiency of breviscapine nanoliposomes was (75.3 +/- 2.3)%.


CONCLUSIONS
The method used in this study is simple, applicable and accurate for determination of the entrapment efficiency of breviscapine nanoliposomes.
Xiong
Fei
F
Institute of Pharmaceutics, China Pharmaceutical University, Nanjing 210009, China.
Zhu
Jia-bi
JB
Wang
Wei
W
Hua
Xiao-bing
XB
D019659:Asteraceae / Q000737:chemistry; D004337:Drug Carriers; D005419:Flavonoids / Q000008:administration & dosage* / Q000737:chemistry / Q000302:isolation & purification; D008081:Liposomes; D036103:Nanotechnology; D010316:Particle Size; D010946:Plants, Medicinal / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*
D004337:Drug Carriers; D005419:Flavonoids; D008081:Liposomes; C061097:breviscapine