title: A new polymer-supported reagent for the synthesis of beta-lactams in solution.
abstract: A modified Mukaiyama reagent was prepared on a PS-DVB resin. This reagent was used for the preparation of beta-lactams, using the Staudinger reaction. The products were obtained by generating the ketene from a carboxylic acid under sonication with the resin followed by reaction with the imine. Excess of the imine was removed by reduction followed by acid scavenging.
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Sassari, Via Vienna 2, 07100 Sassari, Italy.
authors.forename: Donato
authors.initials: D
authors.lastname: Donati
authors.forename: Costanza
authors.initials: C
authors.lastname: Morelli
authors.forename: Andrea
authors.initials: A
authors.lastname: Porcheddu
authors.forename: Maurizio
authors.initials: M
authors.lastname: Taddei
mesh_terms: D007202:Indicators and Reagents / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D012996:Solutions; D047090:beta-Lactams / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D007202:Indicators and Reagents; D011108:Polymers; D012996:Solutions; D047090:beta-Lactams