New cellulose-supported reagent: a sustainable approach to guanidines.
[reaction: see text] A new cellulose-supported reagent for the synthesis of guanidine in aqueous medium is reported starting from commercially available functionalized cellulose beads. Primary and secondary amines, anilines, and amino acids were transformed to the corresponding guanidines in high yields and under very mild conditions.
Porcheddu
Andrea
A
Dipartimento di Chimica, Università degli Studi di Sassari, via Vienna 2, I-07100 Sassari, Italy. anpo@uniss.it
Giacomelli
Giampaolo
G
Chighine
Alessandra
A
Masala
Simonetta
S
D000588:Amines / Q000737:chemistry; D000596:Amino Acids / Q000737:chemistry; D000814:Aniline Compounds / Q000737:chemistry; D002482:Cellulose / Q000737:chemistry*; D006146:Guanidines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
D000588:Amines; D000596:Amino Acids; D000814:Aniline Compounds; D006146:Guanidines; D002482:Cellulose; C023650:aniline