Cytochrome c oxidase, ligands and electrons.
We present hereby an overview of the reactions of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, with ligands (primarily oxygen) and electrons, pointing out where necessary unresolved facts or questionable interpretations.
Brunori
Maurizio
M
Department of Biochemical Sciences A. Rossi Fanelli and CNR Institute of Molecular Biology and Pathology, University of Rome La Sapienza, P. le Aldo Moro, 5, I-00185 Roma, Italia. maurizio.brunori@uniroma1.it
Giuffrè
Alessandro
A
Sarti
Paolo
P
D000818:Animals; D001665:Binding Sites; D003300:Copper / Q000737:chemistry; D004579:Electron Transport / Q000502:physiology; D003576:Electron Transport Complex IV / Q000737:chemistry* / Q000378:metabolism*; D004583:Electrons; D008024:Ligands; D015394:Molecular Structure; D009569:Nitric Oxide / Q000378:metabolism; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry / Q000378:metabolism; D011485:Protein Binding; D011487:Protein Conformation; D011522:Protons
D008024:Ligands; D011522:Protons; D009569:Nitric Oxide; D003300:Copper; D003576:Electron Transport Complex IV; D010100:Oxygen