The optimal time for intracytoplasmic sperm injection in the human is from 37 to 41 hours after administration of human chorionic gonadotropin.
Fertilization rates increased continuously with the time elapsed after administration of hCG, reaching a peak of 84% when intracytoplasmic sperm injection (ICSI) was performed >41 hours after hCG administration. However, the highest implantation rate, 24%, was achieved when ICSI was performed 37-41 hours after hCG administration.
Dozortsev
Dmitri
D
Clinica e Centro de Pesquisa em Reproducao Humana Roger Abdelmassih, São Paulo, Brazil. dmitri@dozortsev.net
Nagy
Peter
P
Abdelmassih
Soraya
S
Oliveira
Flavio
F
Brasil
Amanda
A
Abdelmassih
Vicente
V
Diamond
Michael
M
Abdelmassih
Roger
R
D000328:Adult; D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D010064:Embryo Implantation / Q000187:drug effects*; D005260:Female; D005306:Fertilization / Q000187:drug effects*; D006801:Humans; D008297:Male; D020554:Sperm Injections, Intracytoplasmic; D013997:Time Factors
D006063:Chorionic Gonadotropin