title: Sotalol versus propafenone for long-term maintenance of normal sinus rhythm in patients with recurrent symptomatic atrial fibrillation.
abstract: This prospective, randomized, single-blinded, placebo-controlled study compared the efficacy and safety of sotalol and propafenone when used for long-term prevention of atrial fibrillation. For the long-term maintenance of normal sinus rhythm, propafenone seems to be more effective than sotalol.
authors.affiliation: Cardiology Department, University Hospital of Heraklion, Heraklion, Crete, Greece.
authors.forename: George E
authors.initials: GE
authors.lastname: Kochiadakis
authors.forename: Nikos E
authors.initials: NE
authors.lastname: Igoumenidis
authors.forename: Michail E
authors.initials: ME
authors.lastname: Hamilos
authors.forename: Panagiotis G
authors.initials: PG
authors.lastname: Tzerakis
authors.forename: Nikos C
authors.initials: NC
authors.lastname: Klapsinos
authors.forename: Gregory I
authors.initials: GI
authors.lastname: Chlouverakis
authors.forename: Panos E
authors.initials: PE
authors.lastname: Vardas
mesh_terms: D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011405:Propafenone / Q000627:therapeutic use*; D011446:Prospective Studies; D012008:Recurrence; D012449:Safety; D013015:Sotalol / Q000627:therapeutic use*
chemical_list: D000889:Anti-Arrhythmia Agents; D011405:Propafenone; D013015:Sotalol