Hypokalaemia in ibuprofen and codeine phosphate abuse.
Ibuprofen abuse may be more prevalent than generally considered. Although normally benign, serious complications have been documented. We report an unusual presentation of hypokalaemia and its associated symptoms as a result of Nurofen Plus (200 mg ibuprofen + 12.8 mg codeine phosphate) abuse. Ibuprofen is generally not included in a standard toxicology screen, but should be considered as a rare cause of hypokalaemia.
Dyer
B T
BT
Chelsea & Westminster Hospital, London, UK.
Martin
J L
JL
Mitchell
J L
JL
Sauven
N C
NC
Gazzard
B
B
D018712:Analgesics, Non-Narcotic / Q000009:adverse effects*; D000701:Analgesics, Opioid / Q000009:adverse effects*; D003061:Codeine / Q000009:adverse effects*; D004338:Drug Combinations; D006801:Humans; D007008:Hypokalemia / Q000139:chemically induced*; D007052:Ibuprofen / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D019966:Substance-Related Disorders / Q000150:complications*
D018712:Analgesics, Non-Narcotic; D000701:Analgesics, Opioid; D004338:Drug Combinations; D003061:Codeine; D007052:Ibuprofen