title: Seasonal lethality of the organophosphate pesticide, azamethiphos to female American lobster (Homarus americanus).
abstract: The organophosphate pesticide azamethiphos is the active ingredient in Salmosan, a product formerly registered in Canada for the treatment of cultured Atlantic salmon against infestations of the ectoparasite Lepeophtheirus salmonis. The 48-h LC50 of azamethiphos to female American lobsters was determined bimonthly for 2 years to determine whether the sensitivity of lobsters to azamethiphos varied with time of year, molt stage, or reproductive stage. The LC50's ranged from 0.61 to 3.24 microg/L. The lobsters were most sensitive to azamethiphos during the spawning and molting seasons which occur in the summer and early fall when seawater temperatures are highest. Testing of compounds on this species for regulatory purposes should take into account that there may be variations in sensitivity during the molt and reproductive cycles.
authors.affiliation: Marine Environmental Sciences Division, Fisheries and Oceans Canada, St. Andrews Biological Station, 531 Brandy Cove Rd., St. Andrews, NB, Canada E5B 2L9. burridgel@dfo-mpo.gc.ca
authors.forename: L E
authors.initials: LE
authors.lastname: Burridge
authors.forename: K
authors.initials: K
authors.lastname: Haya
authors.forename: S L
authors.initials: SL
authors.lastname: Waddy
mesh_terms: D000818:Animals; D002170:Canada; D005260:Female; D007928:Lethal Dose 50; D018978:Molting; D008121:Nephropidae / Q000187:drug effects* / Q000502:physiology; D063086:Organothiophosphates / Q000633:toxicity*; D010575:Pesticides / Q000633:toxicity*; D012098:Reproduction; D012621:Seasons; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D063086:Organothiophosphates; D010575:Pesticides; D014874:Water Pollutants, Chemical; C072763:azamethiphos