title: Transient swelling of peripheral nerves in a case of neurosarcoidosis.
abstract: We present a case of neurosarcoidosis showing bilateral carpal tunnel syndrome which disappeared without any medication. This patient was also suffering from motor and sensory disturbance caused by peripheral neuropathy of the four extremities. Magnetic resonance image showed transient swelling of the median nerve, and subperineurial edema was unexpectedly observed in some fascicles in sural nerve biopsy. We hypothesize that the carpal tunnel syndrome in this case was induced by the intercanal high pressure due to edema inside the tunnel, which might be related to the high level of serum IL-2.
authors.affiliation: First Department of Internal Medicine, Section of Neurology, Asahikawa Medical College, Asahikawa.
authors.forename: Setsu
authors.initials: S
authors.lastname: Nakatani-Enomoto
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Aizawa
authors.forename: Satoshi
authors.initials: S
authors.lastname: Koyama
authors.forename: Kenji
authors.initials: K
authors.lastname: Kuroda
authors.forename: Takashi
authors.initials: T
authors.lastname: Kimura
authors.forename: Kenjiro
authors.initials: K
authors.lastname: Kikuchi
mesh_terms: D000368:Aged; D002349:Carpal Tunnel Syndrome / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D010525:Peripheral Nerves / Q000473:pathology; D011115:Polyneuropathies / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D012507:Sarcoidosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids