May 2004: newborn with intracranial mass.
May 2004: We present the case of a male newborn (38th week of gestation) with a 3-week history of a sonographically detected parietal mass of 5-cm diameter. The entire mass was removed at surgery. Surprisingly, microscopy revealed an intracerebral hemorrhage and nests of glycophorin-A immunoreactive blasts and nucleated erythrocytes in the surrounding parenchyma. The final diagnosis was chronic intracerebral hemorrhage of unknown etiology with reactive changes of the surrounding brain tissue and perifocal extramedullary erythropoiesis. This case is unique because, to date, intracranial extramedullary erythropoiesis has only been described in chronic subdural hemorrhage.
Scheil
Stefanie
S
Institute of Pathology, Laboratory of Neuropathology, University Hospitals of Ulm, Germany.
Horn
Torsten
T
Kunz
Ulrich
U
Gabelmann
Andreas
A
Sirén
Anna-Leena
AL
Klein
Rüdiger
R
Schindler
Christoph
C
Möller
Peter
P
Sommer
Clemens
C
D002493:Central Nervous System Diseases / Q000378:metabolism / Q000473:pathology*; D002543:Cerebral Hemorrhage / Q000378:metabolism / Q000473:pathology*; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D016708:Synaptophysin / Q000378:metabolism
D005904:Glial Fibrillary Acidic Protein; D016708:Synaptophysin