Synthesis of cyclopropanes via organoiron methodology: preparation of the C9-C16 alkenylcyclopropane segment of ambruticin.
A synthesis of the C9-C16 segment of ambruticin is described which relies on organoiron methodology to establish the 1,2,3-trisubstituted cyclopropane ring.
Lukesh
Julie M
JM
Department of Chemistry, Marquette University, P.O. Box 1881, Milwaukee, WI 53201-1881, USA.
Donaldson
William A
WA
D000475:Alkenes / Q000737:chemistry; D002625:Chemistry, Organic; D003521:Cyclopropanes / Q000138:chemical synthesis*; D007501:Iron / Q000737:chemistry*; D008024:Ligands; D008956:Models, Chemical; D055601:Organic Chemistry Phenomena; D011714:Pyrans / Q000138:chemical synthesis*
D000475:Alkenes; D003521:Cyclopropanes; D008024:Ligands; D011714:Pyrans; C030797:cyclopropane; D007501:Iron; C014964:ambruticin