title: An unusual mastocytoma with massive eosinophilic infiltration: identification with immunohistochemistry.
abstract: A cutaneous mastocytoma excised from a 6-month-old male infant was found to have unusual massive eosinophilic infiltrates. The mast cells were identified with the aid of immunohistochemistry with antibodies to tryptase and KIT protein (CD117). Massive eosinophilic infiltration in a cutaneous tumor could be a diagnostic clue of an eosinophil-rich mastocytoma.
authors.affiliation: Department of Pathology, Chang Gung Memorial Hospital, Taipei 105, Taiwan.
authors.forename: Shir-Hwa
authors.initials: SH
authors.lastname: Ueng
authors.forename: Tseng-tong
authors.initials: TT
authors.lastname: Kuo
mesh_terms: D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008297:Male; D034801:Mastocytoma / Q000378:metabolism* / Q000473:pathology; D019009:Proto-Oncogene Proteins c-kit / Q000378:metabolism; D012878:Skin Neoplasms / Q000378:metabolism* / Q000473:pathology
chemical_list: D019009:Proto-Oncogene Proteins c-kit