title: Enhancement of ajmalicine production in Catharanthus roseus cell cultures with methyl jasmonate is dependent on timing and dosage of elicitation.
abstract: The optimum growth stage for enhancing ajmalicine production in Catharanthus roseus cultures with methyl jasmonate (MJ) was after 6 d growth. MJ added at 10 or 100 microm on day 6 gave a maximum ajmalicine production of 10.2 mg l(-1), a 300% increase over that of non-elicited cultures.
authors.affiliation: Chemical Engineering Department, 342 Snell Engineering Center, 360 Huntington Avenue, Northeastern University, Boston, MA 02115-5000, USA. clee@coe.neu.edu.
authors.forename: Carolyn W T
authors.initials: CW
authors.lastname: Lee-Parsons
authors.forename: Seda
authors.initials: S
authors.lastname: Ertürk
authors.forename: Jennifer
authors.initials: J
authors.lastname: Tengtrakool
mesh_terms: D000085:Acetates / Q000008:administration & dosage*; D030008:Catharanthus / Q000187:drug effects* / Q000502:physiology*; D049109:Cell Proliferation / Q000187:drug effects; D002478:Cells, Cultured; D003517:Cyclopentanes / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D054883:Oxylipins; D046948:Secologanin Tryptamine Alkaloids / Q000378:metabolism*; D013997:Time Factors
chemical_list: D000085:Acetates; D003517:Cyclopentanes; D054883:Oxylipins; D046948:Secologanin Tryptamine Alkaloids; C005709:raubasine; C072239:methyl jasmonate