title: Acamprosate campral for alcoholism.
abstract: Acamprosate has a different mechanism of action than other drugs used for maintenance of abstinence from alcohol and is generally well tolerated. Diarrhea is the most common adverse effect. Its efficacy in controlled trials has been modest at best, and was poor when patients lacked social support for remaining abstinent. Acomprosate can be used in combination with naltrexone or disulfiram.
mesh_terms: D000077443:Acamprosate; D000427:Alcohol Deterrents / Q000627:therapeutic use*; D000437:Alcoholism / Q000188:drug therapy*; D003967:Diarrhea / Q000139:chemically induced; D004221:Disulfiram / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D009271:Naltrexone / Q000627:therapeutic use; D013654:Taurine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use*
chemical_list: D000427:Alcohol Deterrents; D013654:Taurine; D009271:Naltrexone; D000077443:Acamprosate; D004221:Disulfiram