[A case of sensory ataxic neuropathy and polymyositis of perivascular type associated with Sjögren's syndrome].
A 53-year old woman was admitted with of sensory disturbance and weakness of lower limbs which had progressed slowly in the previous ten years. A diagnosis of sensory ataxic neuropathy associated with Sjögren's syndrome was made. A sural nerve biopsy showed marked loss of myelinated fibers. A muscle biopsy revealed atrophy of muscle fibers along with perivascular cellular infiltration. The dorsal root ganglia have been considered to be the main site affected in the ataxic neuropathy in Sjögren's syndrome. However, the evidence for that was meager. The perivascular inflammatory change observed in the muscle may also have existed in the peripheral nervous system including the dorsal root ganglia.
Taguchi
Takato
T
Department of Neurology, Tokyo Metropolitan Neurological Hospital, 2-6-1 Musashidai, Fuchu, Tokyo 183-0042, Japan.
Matsubara
Shiro
S
Miyamoto
Kazuhito
K
Mizutani
Toshio
T
Hayashi
Hideaki
H
Arakaki
Rieko
R
Hayashi
Yoshio
Y
D001259:Ataxia / Q000150:complications* / Q000473:pathology; D005260:Female; D005727:Ganglia, Spinal / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D010523:Peripheral Nervous System Diseases / Q000150:complications* / Q000473:pathology; D017285:Polymyositis / Q000150:complications* / Q000473:pathology; D012678:Sensation Disorders / Q000150:complications* / Q000473:pathology; D012859:Sjogren's Syndrome / Q000150:complications*