title: VFDB: a reference database for bacterial virulence factors.
abstract: Bacterial pathogens continue to impose a major threat to public health worldwide in the 21st century. Intensified studies on bacterial pathogenesis have greatly expanded our knowledge about the mechanisms of the disease processes at the molecular level over the last decades. To facilitate future research, it becomes necessary to form a database collectively presenting the virulence factors (VFs) of various medical significant bacterial pathogens. The aim of virulence factor database (VFDB) (http://www.mgc.ac.cn/VFs/) is to provide such a source for scientists to rapidly access to current knowledge about VFs from various bacterial pathogens. VFDB is comprehensive and user-friendly. One can search VFDB by browsing each genus or by typing keywords. Furthermore, a BLAST search tool against all known VF-related genes is also available. VFDB provides a unified gateway to store, search, retrieve and update information about VFs from various bacterial pathogens.
authors.affiliation: State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100052, China.
authors.forename: Lihong
authors.initials: L
authors.lastname: Chen
authors.forename: Jian
authors.initials: J
authors.lastname: Yang
authors.forename: Jun
authors.initials: J
authors.lastname: Yu
authors.forename: Zhijian
authors.initials: Z
authors.lastname: Yao
authors.forename: Lilian
authors.initials: L
authors.lastname: Sun
authors.forename: Yan
authors.initials: Y
authors.lastname: Shen
authors.forename: Qi
authors.initials: Q
authors.lastname: Jin
mesh_terms: D001419:Bacteria / Q000235:genetics / Q000472:pathogenicity*; D001426:Bacterial Proteins / Q000737:chemistry; D030541:Databases, Genetic; D005798:Genes, Bacterial; D020407:Internet; D012984:Software; D014584:User-Computer Interface; D037521:Virulence Factors / Q000737:chemistry / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; D037521:Virulence Factors