title: Application of tandem Ugi multi-component reaction/ring closing metathesis to the synthesis of a conformationally restricted cyclic pentapeptide.
abstract: A conformationally restricted cyclic pentapeptide, containing an unsaturated 9-membered lactam as a semi-rigid scaffold, was prepared in a very convergent manner, through tandem Ugi reaction/ring closing metathesis.
authors.affiliation: Department of Chemistry and Industrial Chemistry, via Dodecaneso 31, 16146, Genova, Italy.
authors.forename: Silvia Anthoine
authors.initials: SA
authors.lastname: Dietrich
authors.forename: Luca
authors.initials: L
authors.lastname: Banfi
authors.forename: Andrea
authors.initials: A
authors.lastname: Basso
authors.forename: Gianluca
authors.initials: G
authors.lastname: Damonte
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Guanti
authors.forename: Renata
authors.initials: R
authors.lastname: Riva
mesh_terms: D018360:Crystallography, X-Ray; D003500:Cyclization; D008958:Models, Molecular; D010456:Peptides, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry; D011487:Protein Conformation; D013237:Stereoisomerism
chemical_list: D010456:Peptides, Cyclic