title: [Perioperative targeting brachytherapy for lung cancer invading the chest wall].
abstract: We evaluated the efficacy of perioperative targeting brachytherapy for lung cancer invading the chest wall. Between 1998 and 2003, 7 patients underwent perioperative targeting brachytherapy for lung cancer invading the chest wall. There were 5 male and 2 female patients. The mean age was 63.3 years, with a range of 45 to 77 years. All patients underwent complete resection including the chest wall combined resection. During the operation, plastic afterloading catheters fixed on the Vicryl mesh at interval of 1 cm were placed on the site of chest wall resection. From the third to sixth day after the operation, 15 to 32 Gy of radiation was delivered over 3 or 4 days using a high dose rate remote afterloading system. The area targeted for brachytherapy was determined by a computed tomography (CT) scanner translator with a computer program for radiation planning. The median postoperative hospital stay was 35 days. Local recurrences were observed in 2 patients, but there was no evidence of recurrence in the margin of the resected chest wall. We believe that this short period of treatment and the low side effects enhances the quality of the patients. Prevention of local recurrence was achieved in short term follow-up.
authors.affiliation: Department of General and Cardiothoracic Surgery, School of Medicine, Kanazawa University, Kanazawa, Japan.
authors.forename: Masaya
authors.initials: M
authors.lastname: Takizawa
authors.forename: M
authors.initials: M
authors.lastname: Oda
authors.forename: Y
authors.initials: Y
authors.lastname: Ohta
authors.forename: K
authors.initials: K
authors.lastname: Kawakami
authors.forename: Y
authors.initials: Y
authors.lastname: Tsunezuka
authors.forename: I
authors.initials: I
authors.lastname: Matsumoto
authors.forename: M
authors.initials: M
authors.lastname: Tamura
authors.forename: T
authors.initials: T
authors.lastname: Yachi
authors.forename: G
authors.initials: G
authors.lastname: Watanabe
authors.forename: T
authors.initials: T
authors.lastname: Takanaka
authors.forename: H
authors.initials: H
authors.lastname: Nishijima
authors.forename: O
authors.initials: O
authors.lastname: Matsui
mesh_terms: D000368:Aged; D001918:Brachytherapy; D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology* / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000532:radiotherapy* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control*; D011300:Preoperative Care; D011879:Radiotherapy Dosage; D013899:Thoracic Neoplasms / Q000473:pathology*; D035441:Thoracic Wall