Reductive alkylation of beta-alkoxy aziridines: new route to substituted allylic amines.
[reaction: see text] A new route to substituted cyclic allylic amines via the reductive alkylation of beta-alkoxy aziridines using excess alkyllithium reagents is described.
Rosser
Clare M
CM
Department of Chemistry, University of York, Heslington, York YO10 5DD, UK.
Coote
Susannah C
SC
Kirby
Jonathan P
JP
O'Brien
Peter
P
Caine
Darren
D
D000478:Alkylation; D000498:Allyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D008094:Lithium / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D000498:Allyl Compounds; D000588:Amines; D001388:Aziridines; D009942:Organometallic Compounds; D008094:Lithium