title: A simple and accurate prediction model to estimate the intrahospital mortality risk of hospitalised cancer patients.
abstract: We aimed to form a risk prediction model to assess the probability of intrahospital death in cancer patients at the time of hospitalisation. The medical records and the relevant clinical parameters of cancer patients who died in or who were discharged from a teaching hospital between 1997 and 2000 (n = 334) were reviewed to explore the determinants of intrahospital death, which later were verified prospectively (n = 131). Eastern Cooperative Oncology Group (ECOG) performance status of four, short duration of disease (on a logarithmic scale), emergency admission, low haemoglobin (Hb) value (on a linear scale) and lactate dehydrogenase (LDH) value greater than 378 micro/ml were significantly and independently associated with the risk of intrahospital death. This model had a receiver operating characteristic area of 0.88 in the derivation cohort and 0.82 in the validation cohort. Using readily available clinical parameters, it is possible to devise an accurate and applicable risk prediction model for the hospitalised cancer patients.
authors.affiliation: Department of Medical Oncology, Akdeniz University Medical Faculty, Antalya, Turkey. hbozcuk@antnet.net.tr
authors.forename: H
authors.initials: H
authors.lastname: Bozcuk
authors.forename: E
authors.initials: E
authors.lastname: Koyuncu
authors.forename: M
authors.initials: M
authors.lastname: Yildiz
authors.forename: M
authors.initials: M
authors.lastname: Samur
authors.forename: M
authors.initials: M
authors.lastname: Ozdogan
authors.forename: M
authors.initials: M
authors.lastname: Artaç
authors.forename: E
authors.initials: E
authors.lastname: Coban
authors.forename: B
authors.initials: B
authors.lastname: Savas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003625:Data Collection / Q000592:standards; D004812:Epidemiologic Methods; D005260:Female; D017052:Hospital Mortality; D006784:Hospitals, Teaching; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000401:mortality*; D011379:Prognosis; D018570:Risk Assessment / Q000379:methods / Q000592:standards; D014421:Turkey / Q000453:epidemiology