title: [Establishment of canine models of penetrating craniocerebral gunshot wound].
abstract: OBJECTIVE
  To establish a canine model of penetrating craniocerebral gunshot wound.
  
  
  METHODS
  Gunshot wound was induced in 54 cross-bred dogs using 7.62-mm pistol bullets fired using a pistol from a distance of 30 cm in coronal direction with a tilt of 10 degrees toward the orbit, causing penetrating craniocerebral injury 1 cm posterior and 1.5 cm superior to the lateral canthus. The breathing and pathological changes in the brain tissue were observed after the injury.
  
  
  RESULTS
  Autonomous breathing was recovered in 9 out of 21 dogs with respiratory arrest after the injury, and the total survival rate was 77.8% in the 54 dogs after the injury. Intracranial hematoma, intracranial pneumatosis, contusion and laceration of brain, and cranial bone fragments were found by cranial CT, with the entrance and exit of the bullet seen on the right and left frontal bone respectively. Pathological examination showed contusion and laceration of the brain tissues.
  
  
  CONCLUSIONS
  The model of craniocerebral perforating wound has been successfully established in dogs.
authors.affiliation: Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. xty64@126.com
authors.forename: Li
authors.initials: L
authors.lastname: Yu
authors.forename: Ru-xiang
authors.initials: RX
authors.lastname: Xu
authors.forename: Ping
authors.initials: P
authors.lastname: Peng
authors.forename: Pei-zeng
authors.initials: PZ
authors.lastname: Xie
authors.forename: Hong-sheng
authors.initials: HS
authors.lastname: Zhu
authors.forename: Song-qing
authors.initials: SQ
authors.lastname: Wang
mesh_terms: D000818:Animals; D006259:Craniocerebral Trauma; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D008297:Male; D014948:Wounds, Gunshot; D014950:Wounds, Penetrating