Triethylsilane-indium(III) chloride system as a radical reagent.
[reaction: see text] A novel generation method of indium hydride (Cl2InH) was found by the transmetalation of InCl3 with Et3SiH. In the intramolecular cyclization of enynes, the previously reported system (NaBH4-InCl3) has a problem of side reactions with the coexistent borane. In contrast, the problem was solved by the presented system, which affords effective hydroindation of alkynes.
Hayashi
Naoki
N
Department of Molecular Chemistry, Science and Technology Center for Atoms, Molecules and Ions Control (STAMIC), Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Shibata
Ikuya
I
Baba
Akio
A