title: [Protective effect of lycopene on the oxidative damage of lung in rat induced by ozone].
abstract: OBJECTIVE
  To observe the effect of Lycopene (LP) on the oxidative damage of lung induced by exposing ozone.
  
  
  METHODS
  The injury model of lung was induced by exposing ozone. The xanthines oxidize method and TBA was used to determine SOD, MDA and GSH-Px in serum and lung respectively.
  
  
  RESULTS
  Compared with model rats, SOD and GSH-Px in the group of LP administrated were increased and MDA were decreased significantly (P < 0.05).
  
  
  CONCLUSIONS
  it was showed that LP could protect oxidative damage of lung induced by ozone in rats.
authors.affiliation: School of Public Health, Harbin Medical University, Harbin 150001, China.
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Pan
authors.forename: Likui
authors.initials: L
authors.lastname: Wan
authors.forename: Shengbo
authors.initials: S
authors.lastname: Sun
authors.forename: Lixin
authors.initials: L
authors.lastname: Na
authors.forename: Shengsan
authors.initials: S
authors.lastname: Li
authors.forename: Jun
authors.initials: J
authors.lastname: Cao
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002338:Carotenoids / Q000494:pharmacology*; D005979:Glutathione Peroxidase / Q000378:metabolism; D008168:Lung / Q000187:drug effects* / Q000378:metabolism; D000077276:Lycopene; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D018384:Oxidative Stress / Q000187:drug effects*; D010126:Ozone / Q000633:toxicity*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013482:Superoxide Dismutase / Q000378:metabolism
chemical_list: D000975:Antioxidants; D002338:Carotenoids; D008315:Malondialdehyde; D010126:Ozone; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D000077276:Lycopene