title: Solitary splenic metastasis of squamous cell carcinoma of the uterine cervix: a case report and review of the literature.
abstract: A 45-year-old patient presented with complaints of vaginal bleeding and pelvic pain. Fractioned probe curettage was performed and reported as Stage IIa, grade 3, squamous cell carcinoma of the uterine cervix. The patient underwent radical hysterectomy type III, bilateral salpingo-oophorectomy, omentectomy, appendectomy, and pelvic para-aortic lymph node dissection according to our clinical protocol. Adjuvant radiation therapy was planned. A splenic mass of 8 cm in diameter was revealed on computed tomography at the end of the third year of the disease-free follow-up period. Fine needle aspiration biopsy was performed and reported as metastatic carcinoma correlated to the previous cervical cancer. Debulking surgery was performed. The patient died one year after the second surgical operation. Spleen metastasis in patients with squamous cell carcinoma of the uterine cervix is exceedingly rare. Nonetheless we recommend screening of all intra-abdominal organs including the spleen as a rare metastastic site in follow-up examination protocols.
authors.affiliation: Department of Obstetrics & Gynecology, Gülhane Military Medical Academy, Etlik/Ankara, Turkey.
authors.forename: U
authors.initials: U
authors.lastname: Goktolga
authors.forename: M
authors.initials: M
authors.lastname: Dede
authors.forename: G
authors.initials: G
authors.lastname: Deveci
authors.forename: M C
authors.initials: MC
authors.lastname: Yenen
authors.forename: M S
authors.initials: MS
authors.lastname: Deveci
authors.forename: S
authors.initials: S
authors.lastname: Dilek
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000175:diagnosis* / Q000556:secondary / Q000628:therapy; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D009362:Neoplasm Metastasis; D017699:Pelvic Pain / Q000209:etiology; D013160:Splenic Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000556:secondary / Q000628:therapy; D002583:Uterine Cervical Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D014592:Uterine Hemorrhage / Q000209:etiology