High prevalence of ciprofloxacin-resistant Neisseria gonorrhoeae in Northern Taiwan.
Among 55 preserved isolates collected in northern Taiwan from 1999 through 2003, ciprofloxacin resistance (minimum inhibitory concentration, >or=1 microg/mL) was found in 1 (25%) of 4 isolates obtained in 1999-2000 and in 27 (93.1%) of 29 isolates obtained in 2003. Pulsed-field gel electrophoresis analysis indicated that several clones predominated among the ciprofloxacin-resistant isolates.
Hsueh
Po-Ren
PR
Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan. hsporen@ha.mc.ntu.edu.tw
Tseng
Sung-Pin
SP
Teng
Lee-Jene
LJ
Ho
Shen-Wu
SW
D000328:Adult; D000890:Anti-Infective Agents / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology*; D004352:Drug Resistance, Microbial / Q000502:physiology*; D005260:Female; D006069:Gonorrhea / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009344:Neisseria gonorrhoeae / Q000187:drug effects* / Q000302:isolation & purification; D015995:Prevalence; D013624:Taiwan / Q000453:epidemiology
D000890:Anti-Infective Agents; D002939:Ciprofloxacin