title: A comparative study of preload-adjusted maximal and peak power: assessment of ventricular performance in clinical practice.
abstract: This study was performed to determine whether preload-adjusted peak power can act as a surrogate for preload-adjusted maximal power in the assessment of left ventricular performance in the clinical setting. Ninety-nine consecutive patients who had undergone elective coronary artery bypass grafting were studied. Fifty-five of these patients were divided into four study groups. Afterload was changed with phenylephrine (n = 12) or glyceryl trinitrate (n = 13), preload was increased with intravenous colloid (n = 18), and contractility was increased with dobutamine (n = 12). There was excellent correlation between the two indices (r = 0.99, y = 1.0168x + 0.0769; p < 0.0001). Manipulation of neither preload nor afterload affected the indices. Both indices increased significantly during dobutamine infusion (p = 0.002). In conclusion, preload-adjusted peak power can be used as a substitute for preload-adjusted maximal power in the determination of ventricular performance in clinical practice.
authors.affiliation: Institute Biomedical Technology, Ghent University, Ghent, Belgium.
authors.forename: R
authors.initials: R
authors.lastname: Amà
authors.forename: T
authors.initials: T
authors.lastname: Claessens
authors.forename: C
authors.initials: C
authors.lastname: Roosens
authors.forename: P
authors.initials: P
authors.lastname: Segers
authors.forename: P
authors.initials: P
authors.lastname: Verdonck
authors.forename: J
authors.initials: J
authors.lastname: Poelaert
mesh_terms: D002316:Cardiotonic Agents; D001026:Coronary Artery Bypass; D004280:Dobutamine; D005780:Gelatin; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D009200:Myocardial Contraction; D005996:Nitroglycerin; D010656:Phenylephrine; D011184:Postoperative Period; D015203:Reproducibility of Results; D016277:Ventricular Function, Left / Q000187:drug effects
chemical_list: D002316:Cardiotonic Agents; D010656:Phenylephrine; D004280:Dobutamine; D005780:Gelatin; D005996:Nitroglycerin