[VGKC antibodies associated with limbic encephalitis].
Since the initial description of limbic encephalitis (LE) in 1960/1968, several subforms of this clinico-neuropathological syndrome have been identified. The best known is paraneoplastic LE. However, non-paraneoplastic forms have been reported, too. Very recently, autoantibodies against voltage-gated potassium channels have been described in association with LE. The diagnostic workup of such a case and the apparently typical good response to long-term immunotherapy of this LE subform are described.
Soeder
B M
BM
Klinik für Epileptologie, Universität Bonn.
Urbach
H
H
Elger
C E
CE
Bien
C G
CG
Beyenburg
S
S
D000906:Antibodies / Q000097:blood* / Q000276:immunology*; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D020363:Limbic Encephalitis / Q000175:diagnosis* / Q000276:immunology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D024642:Potassium Channels, Voltage-Gated / Q000276:immunology*
D000906:Antibodies; D024642:Potassium Channels, Voltage-Gated