HAART-prolonged life of HIV-infected patients should not be shortened by hepatitis C.
As highly active antiretroviral treatment (HAART) prolongs the life of HIV-infected individuals and reduces mortality associated with opportunistic infections, liver diseases have become a major challenge in the management of these patients. up to 45% of deaths of persons with HIV are related to endstage liver disease, some of which might have been avoided with a less hesitant approach to hepatitis C treatment in the setting of HIV/ hepatitis C (HCV) coinfection.
Horster
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Dept. of Infectious Diseases, Medical Policlinic, Ludwig Maximilian University Munich, Pettenkoferstr. 8a, D-80336 Munich, Germany.
Goebel
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FD
D023241:Antiretroviral Therapy, Highly Active; D015897:Comorbidity; D015658:HIV Infections / Q000150:complications* / Q000821:virology; D006526:Hepatitis C / Q000401:mortality* / Q000473:pathology; D006801:Humans; D008017:Life Expectancy; D011379:Prognosis