title: Clinicopathological features of gastric carcinoma patients with other primary carcinomas.
abstract: BACKGROUND
  Multiple primary carcinomas are increasingly being found because of the development of diagnostic techniques and the increasing incidence of early stage carcinoma. The purpose of this study was to determine the prevalence and clinicopathological features of gastric carcinoma patients with other primary carcinomas.
  
  
  METHODS
  There were 65 (incidence 2.6%) gastric carcinoma patients with other primary carcinomas compared with 2,444 patients with gastric carcinoma alone.
  
  
  RESULTS
  Associated primary carcinomas were often found in the gastrointestinal (GI) tract, especially in the colon (33.8%). In patients with gastric carcinoma only, poorly differentiated adenocarcinoma was the most common (43.2%), followed by moderately and well-differentiated adenocarcinoma. Similarly, poorly differentiated adenocarcinoma (33.8%) was also the prevalent histological type in gastric carcinoma patients with other primary carcinomas, although its incidence was lower. The stage of gastric carcinoma did not differ between the two groups. The estimated 5-year survival rate was 51.6% for patients with gastric carcinoma alone, and 50.7% for those with other primary carcinomas; the difference was not significant (P=0.82).
  
  
  CONCLUSIONS
  Gastric carcinoma should be treated aggressively, since the prognosis of gastric carcinoma patients treated for other primary carcinomas is not poorer than that of patients treated for gastric carcinoma alone.
authors.affiliation: Division of Gastroenterologic Surgery, Department of Surgery, Chonnam National University Medical School, 8, Hakdong, Dongku, Gwangju, 501-757, South Korea.
authors.forename: Young Kyu
authors.initials: YK
authors.lastname: Park
authors.forename: Dong Yi
authors.initials: DY
authors.lastname: Kim
authors.forename: Jae Kyoon
authors.initials: JK
authors.lastname: Joo
authors.forename: Jung Chul
authors.initials: JC
authors.lastname: Kim
authors.forename: Yang Suk
authors.initials: YS
authors.lastname: Koh
authors.forename: Seong Yeob
authors.initials: SY
authors.lastname: Ryu
authors.forename: Young Jin
authors.initials: YJ
authors.lastname: Kim
authors.forename: Shin Kon
authors.initials: SK
authors.lastname: Kim
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D016609:Neoplasms, Second Primary / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D015995:Prevalence; D013274:Stomach Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D016019:Survival Analysis