[The effects of traditional Chinese medicines on the adherence of Streptococcus mutans to salivary acquired pellicle in vitro].
OBJECTIVE
To investigate the effects of traditional Chinese medicines on the preliminary adherence of Streptococcus mutans to salivary acquired pellicles.


METHODS
The hydroxyapatites beads were coated by saliva to form S-HA, an in vitro model of experimental pellicle. Streptococcus mutans was chosen as the experiment strain, and radiolabeled with 3H-thymidine. Two parts of adherence inhibit study were carried on with medicines pretreated S-HA and medicines pretreated bacteria. The numbers of 3H-thymidine labeled bacteria attached to S-HA were counted by scintillation counting to indicate the amount of adherence.


RESULTS
It was found that most of the traditional Chinese medicines tested could inhibit the adherence to S-HA to different extent, especially the Galla Chinensis, which has significant inhibitory action.


CONCLUSIONS
Galla Chinensis may be a prospective medicine to inhibit the cariogenic bacteria's preliminary adherence to salivary acquired pellicles.
Huang
Zhengwei
Z
West China School of Stomatology, Sichuan University, Chengdu 610041, China.
Zhou
Xuedong
X
Li
Jiyao
J
Liu
Tianjia
T
Li
Hong
H
Zhu
Bing
B
D001422:Bacterial Adhesion / Q000187:drug effects*; D002327:Cariostatic Agents / Q000494:pharmacology; D003731:Dental Caries / Q000382:microbiology*; D044622:Dental Pellicle; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D006801:Humans; D006882:Hydroxyapatites; D012463:Saliva / Q000382:microbiology; D013295:Streptococcus mutans / Q000187:drug effects*
D002327:Cariostatic Agents; D004365:Drugs, Chinese Herbal; D006882:Hydroxyapatites