title: Dichloromethane activation. Direct methylenation of ketones and aldehydes with CH2Cl2 promoted by Mg/TiCl4/THF.
abstract: [reaction: see text] This Mg-TiCl4-promoted CH2-transfer reaction of CH2Cl2 represents an extremely simple, practical, and efficient methylenation of a variety of ketones and aldehydes, especially in enolizable or sterically hindered ketones such as 2,2-dimethylcyclohexanone, camphor, and fenchone.
authors.affiliation: Department of Chemistry, National Chung-Hsing University, Taichung 400, Taiwan, Republic of China. thyan@mail.nchu.edu.tw
authors.forename: Tu-Hsin
authors.initials: TH
authors.lastname: Yan
authors.forename: Chia-Chung
authors.initials: CC
authors.lastname: Tsai
authors.forename: Ching-Ting
authors.initials: CT
authors.lastname: Chien
authors.forename: Chia-Ching
authors.initials: CC
authors.lastname: Cho
authors.forename: Pei-Chen
authors.initials: PC
authors.lastname: Huang