Allylthiosulfinate: beta-cyclodextrin inclusion complex: preparation, characterization and microbiological activity.
An allylthiosulfinate: beta-cyclodextrin inclusion complex was synthesized and characterized using X-ray crystallography, IR spectroscopy, thermal analysis and nuclear magnetic resonance. The microbiological activity of the complex was tested on available fungi (Candida albicans ATCC 10231, Aspergillus niger ATCC 16404) and bacteria (Staphylococcus aureus ATCC 6538, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 9027). In small concentrations, the complex inhibited the growth of the microorganisms tested. The most susceptible microorganism was Candida albicans ATCC 10231, and the least susceptible Pseudomonas aeruginosa ATCC 9027.
Nikolic
V
V
Faculty of Technology, University of Nish, Leskovac, Serbia and Montenegro. nvesna@yahoo.com
Stankovic
M
M
Kapor
A
A
Nikolic
Lj
Lj
Cvetkovic
D
D
Stamenković
J
J
D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D018360:Crystallography, X-Ray; D004220:Disulfides; D004355:Drug Stability; D005658:Fungi / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D012995:Solubility; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013441:Sulfinic Acids / Q000138:chemical synthesis* / Q000494:pharmacology*; D013818:Thermogravimetry; D047392:beta-Cyclodextrins / Q000138:chemical synthesis* / Q000494:pharmacology*
D000890:Anti-Infective Agents; D004220:Disulfides; D013441:Sulfinic Acids; D047392:beta-Cyclodextrins; C006452:allicin; C031215:betadex