title: MetaRouter: bioinformatics for bioremediation.
abstract: Bioremediation, the exploitation of biological catalysts (mostly microorganisms) for removing pollutants from the environment, requires the integration of huge amounts of data from different sources. We have developed MetaRouter, a system for maintaining heterogeneous information related to bioremediation in a framework that allows its query, administration and mining (application of methods for extracting new knowledge). MetaRouter is an application intended for laboratories working in biodegradation and bioremediation, which need to maintain and consult public and private data, linked internally and with external databases, and to extract new information from it. Among the data-mining features is a program included for locating biodegradative pathways for chemical compounds according to a given set of constraints and requirements. The integration of biodegradation information with the corresponding protein and genome data provides a suitable framework for studying the global properties of the bioremediation network. The system can be accessed and administrated through a web interface. The full-featured system (except administration facilities) is freely available at http://pdg.cnb.uam.es/MetaRouter. Additional material: http://www.pdg.cnb.uam.es/biodeg_net/MetaRouter.
authors.affiliation: Department of Biological Sciences, Structural Bioinformatics Group, Biochemistry Building, Imperial College, London SW7 2AZ, UK. f.pazos@imperial.ac.uk
authors.forename: Florencio
authors.initials: F
authors.lastname: Pazos
authors.forename: David
authors.initials: D
authors.lastname: Guijas
authors.forename: Alfonso
authors.initials: A
authors.lastname: Valencia
authors.forename: Victor
authors.initials: V
authors.lastname: De Lorenzo
mesh_terms: D001419:Bacteria / Q000235:genetics / Q000378:metabolism; D001673:Biodegradation, Environmental; D019295:Computational Biology; D016208:Databases, Factual; D004783:Environmental Microbiology; D004785:Environmental Pollutants / Q000378:metabolism*; D023281:Genomics; D020407:Internet; D018511:Systems Integration; D014584:User-Computer Interface
chemical_list: D004785:Environmental Pollutants