title: Advances in surface-enhanced fluorescence.
abstract: We report recent achievements in metal-enhanced fluorescence from our laboratory. Several fluorophore systems have been studied on metal particle-coated surfaces and in colloid suspensions. In particular, we describe a distance dependent enhancement on silver island films (SIFs), release of self-quenching of fluorescence near silver particles, and the applications of fluorescence enhancement near metalized surfaces to bioassays. We discuss a number of methods for various shaped silver particle deposition on surfaces.
authors.affiliation: Department of Biochemistry and Molecular Biology, Center for Fluorescence Spectroscopy, University of Maryland, 725 West Lombard Street, Baltimore, Maryland 21201, USA. lakowicz@cfs.umbi.umd.edu
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Lakowicz
authors.forename: Chris D
authors.initials: CD
authors.lastname: Geddes
authors.forename: Ignacy
authors.initials: I
authors.lastname: Gryczynski
authors.forename: Joanna
authors.initials: J
authors.lastname: Malicka
authors.forename: Zygmunt
authors.initials: Z
authors.lastname: Gryczynski
authors.forename: Kadir
authors.initials: K
authors.lastname: Aslan
authors.forename: Joanna
authors.initials: J
authors.lastname: Lukomska
authors.forename: Evgenia
authors.initials: E
authors.lastname: Matveeva
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.forename: Ramachandram
authors.initials: R
authors.lastname: Badugu
authors.forename: Jun
authors.initials: J
authors.lastname: Huang
mesh_terms: D000465:Algorithms; D001360:Avidin / Q000737:chemistry; D001710:Biotin / Q000737:chemistry; D003102:Colloids / Q000737:chemistry; D004247:DNA / Q000032:analysis / Q000737:chemistry; D004563:Electrochemistry; D005453:Fluorescence; D031541:Fluorescence Resonance Energy Transfer; D005456:Fluorescent Dyes / Q000737:chemistry / Q000528:radiation effects; D008670:Metals / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D049329:Nanostructures / Q000737:chemistry; D036103:Nanotechnology / Q000379:methods*; D009693:Nucleic Acid Hybridization / Q000379:methods; D010777:Photochemistry; D012710:Serum Albumin, Bovine / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013499:Surface Properties
chemical_list: D003102:Colloids; D005456:Fluorescent Dyes; D008670:Metals; D001360:Avidin; D012710:Serum Albumin, Bovine; D012834:Silver; D001710:Biotin; D004247:DNA