title: Clinicopathologic case report: scleral buckle associated nontuberculous mycobacterial scleritis.
abstract: Nontuberculous mycobacterial (NTM) infections have become increasingly important in ophthalmology, particularly with keratorefractive surgery. We report a case of scleral buckle associated NTM scleritis occurring in a 69-year-old male after silicone sponge explant removal. Purulent scleral ulceration with nodule formation persisted despite topical antimicrobial therapy, buckle removal, and surgical debridement. Eventually, tissue biopsy revealed noncasseating granulomas with acid-fast bacilli that were identified in culture as Mycobacterium chelonae. The infection resolved only after administration of systemic antibiotics. NTM are important pathogens in scleral buckle associated scleritis and should be considered in persistent cases. Surgical therapy remains the cornerstone of therapy, but antimicrobials, particularly newer fourth generation fluoroqunilones, may have an important role in treating scleral buckle associated NTM scleritis.
authors.affiliation: Department of Ophthalmology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 60153, USA.
authors.forename: Jared S
authors.initials: JS
authors.lastname: Nielsen
authors.forename: Steven
authors.initials: S
authors.lastname: Blatt
authors.forename: Jay I
authors.initials: JI
authors.lastname: Perlman
authors.forename: Richard G
authors.initials: RG
authors.lastname: Gieser
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents; D003646:Debridement; D020878:Device Removal; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D016926:Mycobacterium chelonae / Q000302:isolation & purification*; D012086:Reoperation; D012163:Retinal Detachment / Q000601:surgery; D012591:Scleral Buckling / Q000009:adverse effects*; D015423:Scleritis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents