title: Romifidine-ketamine anaesthesia in atropine and triflupromazine pre-medicated buffalo calves.
abstract: The study was conducted on 10 buffalo calves with a weight of 98.5 +/- 3.9 kg and age 9.7 +/- 1.3 months. Ten trials of two treatments were carried out using a randomized block design. Atropine at the dose of 0.02 mg/kg bodyweight was administered in both the groups. The animals of group I received romifidine at the dose of 10 microg/kg i.v., 10 min after atropine administration, whereas, animals of group II received triflupromazine at the dose of 0.3 mg/kg i.m. and 10 min later romifidine at the dose of 10 microg/kg i.v. immediately followed by ketamine at the dose of 5 mg/kg i.v. The onset of action of romifidine in group I occurred within 2 min and the animals remained under mild sedation for 31 +/- 4.8 min. In group II, the triflupromazine-romifidine-ketamine combination induced anaesthesia for 14 +/- 2.3 min. Hypothermia, significant bradycardia and respiratory depression was noticed in both groups at different time intervals.
authors.affiliation: Division of Surgery, Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, India.
authors.forename: A K
authors.initials: AK
authors.lastname: Sharma
authors.forename: N
authors.initials: N
authors.lastname: Kumar
authors.forename: U
authors.initials: U
authors.lastname: Dimri
authors.forename: M
authors.initials: M
authors.lastname: Hoque
authors.forename: S K
authors.initials: SK
authors.lastname: Maiti
authors.forename: O P
authors.initials: OP
authors.lastname: Gupta
authors.forename: A
authors.initials: A
authors.lastname: Shahi
mesh_terms: D000759:Adjuvants, Anesthesia / Q000009:adverse effects; D000758:Anesthesia / Q000379:methods / Q000662:veterinary*; D000778:Anesthetics, Dissociative / Q000009:adverse effects; D000818:Animals; D001285:Atropine / Q000009:adverse effects; D001919:Bradycardia / Q000139:chemically induced / Q000662:veterinary; D002020:Buffaloes / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D006339:Heart Rate / Q000187:drug effects; D007035:Hypothermia / Q000139:chemically induced / Q000662:veterinary; D007093:Imidazoles / Q000009:adverse effects; D007649:Ketamine / Q000009:adverse effects; D008297:Male; D011229:Preanesthetic Medication / Q000662:veterinary*; D011897:Random Allocation; D014273:Triflupromazine / Q000009:adverse effects
chemical_list: D000759:Adjuvants, Anesthesia; D000778:Anesthetics, Dissociative; D007093:Imidazoles; D007649:Ketamine; D001285:Atropine; C076257:romifidine; D014273:Triflupromazine