Inclusion complex formation between alpha-cyclodextrin and biodegradable aliphatic polyesters.
Inclusion complexes (ICs) between alpha-cyclodextrin (alpha-CD) and three kinds of biodegradable aliphatic polyesters with different sequence lengths of the monomeric repeating units poly(3-hydroxypropionate) [P(3HP)], poly(4-hydroxybutyrate) [P(4HB)] and poly(epsilon-caprolactone)(PCL) were prepared by mixing a solution of alpha-CD with that of the polymer, followed by stirring. The ICs were obtained as insoluble precipitates and characterized by FT-IR, WAXD and DSC. All measurements showed that the polymer chains of all three kinds of polyester were included into the alpha-CD cavity and formed ICs with different stoichiometries. WAXD patterns and thermal analysis indicated that these ICs possessed a channel structure and the crystallization of the polyester chains was suppressed upon inclusion into the alpha-CD cavity.
Shin
Kyung-Moo
KM
Department of Biomolecular Engineering, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8501, Japan.
Dong
Tungalag
T
He
Yong
Y
Taguchi
Yoichi
Y
Oishi
Akihiro
A
Nishida
Haruo
H
Inoue
Yoshio
Y
D001673:Biodegradation, Environmental; D002152:Calorimetry, Differential Scanning; D003460:Crystallization; D006860:Hydrogen Bonding; D046911:Macromolecular Substances; D009682:Magnetic Resonance Spectroscopy; D011091:Polyesters / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D017550:Spectroscopy, Fourier Transform Infrared; D013696:Temperature; D014961:X-Ray Diffraction; D047391:alpha-Cyclodextrins / Q000032:analysis / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism
D046911:Macromolecular Substances; D011091:Polyesters; D047391:alpha-Cyclodextrins; C032613:alpha-cyclodextrin