title: Neuroblastoma update.
abstract: OBJECTIVE
  The purpose of this paper is to review the most recent medical literature pertaining to neuroblastoma. Clinically, progress continues to be made on the refinement of radiographic staging and risk stratification-based treatment.
  
  
  RESULTS
  Meanwhile, experimental efforts focus on the continued search for biologic prognostic markers and the development of novel therapies including second-generation retinoids, tumor vaccines, and new modes of drug delivery with improved safety and efficacy.
  
  
  CONCLUSIONS
  Review of the recent neuroblastoma literature demonstrates continued progress in our ability to understand and treat this enigmatic tumor.
authors.affiliation: Section of Pediatric Surgery, Yale University School of Medicine, New Haven, CT 06520-8062, USA.
authors.forename: Marion C W
authors.initials: MC
authors.lastname: Henry
authors.forename: David B
authors.initials: DB
authors.lastname: Tashjian
authors.forename: Christopher K
authors.initials: CK
authors.lastname: Breuer
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis*; D006801:Humans; D009367:Neoplasm Staging / Q000379:methods*; D009447:Neuroblastoma / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D011379:Prognosis; D018570:Risk Assessment
chemical_list: D014408:Biomarkers, Tumor