title: [Clinical observation on treatment of chronic suppurative otitis media caused large tympanic membranes perforation by ear-dropping with combined Chinese and Western drugs].
abstract: OBJECTIVE
  To observe the therapeutic effect of the self-prepared ear dropping made by combined Chinese and Western drugs in treating chronic suppurative otitis media caused large tympanic membrane perforation.
  
  
  METHODS
  Sixty-four patients were randomly divided into two groups, the treated group treated with the self-prepared ear-dropping and the control group treated with ear-dropping made by placebo, to observe the therapeutic effect and adverse reaction.
  
  
  RESULTS
  In the 32 patients of the treated group, 15 patients were cured, the cured tympanic membrane was normal in shape and thickness in 11, scarred in 3, and thin and transparent in 1. The hearing was improved in all patients with cured tympanic membrane. But no one was cured in the control group.
  
  
  CONCLUSIONS
  The self-prepared ear-dropping had good effect in treating tympanic membrane perforation, it is simple, cheap and no need of further operation.
authors.affiliation: Department of Otorhinolaryngology and Head Neck Surgery, The First Affiliated People's Hospital of Jiaotong University, Shanghai (200080). likeyong5@yahoo.com.cn
authors.forename: Ke-yong
authors.initials: KY
authors.lastname: Li
authors.forename: Ning-jun
authors.initials: NJ
authors.lastname: Zhao
authors.forename: Jiang-cai
authors.initials: JC
authors.lastname: Zhu
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010035:Otitis Media, Suppurative / Q000150:complications / Q000188:drug therapy*; D008517:Phytotherapy; D018058:Tympanic Membrane Perforation / Q000188:drug therapy* / Q000209:etiology
chemical_list: D004365:Drugs, Chinese Herbal