Receptive field size and response latency are correlated within the cat visual thalamus.
Each point in visual space is encoded at the level of the thalamus by a group of neighboring cells with overlapping receptive fields. Here we show that the receptive fields of these cells differ in size and response latency but not at random. We have found that in the cat lateral geniculate nucleus (LGN) the receptive field size and response latency of neighboring neurons are significantly correlated: the larger the receptive field, the faster the response to visual stimuli. This correlation is widespread in LGN. It is found in groups of cells belonging to the same type (e.g., Y cells), and of different types (i.e., X and Y), within a specific layer or across different layers. These results indicate that the inputs from the multiple geniculate afferents that converge onto a cortical cell (approximately 30) are likely to arrive in a sequence determined by the receptive field size of the geniculate afferents. Recent studies have shown that the peak of the spatial frequency tuning of a cortical cell shifts toward higher frequencies as the response progresses in time. Our results are consistent with the idea that these shifts in spatial frequency tuning arise from differences in the response time course of the thalamic inputs.
Weng
Chong
C
Department of Biological Sciences, State University of New York-State College of Optometry, 33 West 42nd Street, New York, NY 10036, USA.
Yeh
Chun-I
CI
Stoelzel
Carl R
CR
Alonso
Jose-Manuel
JM
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001931:Brain Mapping; D002415:Cats; D002452:Cell Count / Q000379:methods; D003198:Computer Simulation; D005829:Geniculate Bodies / Q000166:cytology*; D009010:Monte Carlo Method; D009474:Neurons / Q000145:classification / Q000502:physiology*; D010775:Photic Stimulation / Q000379:methods; D011930:Reaction Time / Q000502:physiology*; D013028:Space Perception / Q000502:physiology; D013223:Statistics as Topic; D013997:Time Factors; D014794:Visual Fields / Q000502:physiology*