[Analysis of polymorphism of ACTBP2 locus in Han population in Chengdu and triplexing of three STR loci].
OBJECTIVE
To obtain the polymorphism of ACTBP2 locus in Han Chinese in Chengdu and establish the triplexing of three STR loci (DHFRP2,FIBRA and ACTBP2).


METHODS
Amp-FLP, PAGE and silver stain were used to analyze 147 individuals.


RESULTS
Twenty alleles and 86 genotypes were observed in ACTBP2. The discriminating power (DP), observed heterozygosity(h), polymorphism information content (PIC) and chance of paternity exclusion power (EP) were 0.9861, 0.9728, 0.9310 and 0.8203, respectively. The distributions of the genotypes were in good agreement with Hardy-Weinberg equilibrium. Studies of the families revealed that the locus was in accord with the Mendelian law.


CONCLUSIONS
These data indicate that ACTBP2 is of good polymorphism and can be applied to human genetic study, forensic parentage testing and identification.
Xu
Zhenbo
Z
The Research Institution of Forensic Science and Technology, Shenzhen Police Bureau, Shenzhen 518001, China.
Chen
Lin
L
Wu
Meiyun
M
Sun
Guangyun
G
Li
Xiaobin
X
Lai
Yue
Y
Hu
Haiyang
H
Wang
Xin
X
D000483:Alleles; D044466:Asian People / Q000235:genetics*; D002681:China / Q000208:ethnology; D005260:Female; D005554:Forensic Medicine; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences / Q000235:genetics*