title: Surgical treatment of Buerger's disease.
abstract: We aimed to evaluate the characteristics of 198 new patients with Buerger's disease treated surgically in the last decade. We also compared these results with our former series reported in 1993. The records of patients with Buerger's disease who were enrolled in an ongoing investigational protocol between 1991 and 2001 were reviewed. Sympathectomy was carried out in 161 patients and revascularization in 19 patients. The cumulative secondary patency rate was 57.9% for bypass grafts at a mean follow-up of 5.4 years. Clinical outcome following sympathectomy was considered improved in 52.3% of patients, stable in 27.8%, and worse in 19.8%. Seven major and 36 minor amputations were performed, with a limb salvage rate of 95.6%. The aggressiveness of the disease has increased compared with previous series, parallel to the expansion of cigarette consumption. Bypass surgery should be considered for patients with severe ischemia who have target vessels. Sympathectomy still has a role to improve distal flow.
authors.affiliation: Department of Cardiovascular Surgery, Istanbul University Cerrahpasa Medical School, Istanbul, Turkey. akbozkurt@yahoo.com
authors.forename: A Kürşat
authors.initials: AK
authors.lastname: Bozkurt
authors.forename: Kazim
authors.initials: K
authors.lastname: Beşirli
authors.forename: Cengiz
authors.initials: C
authors.lastname: Köksal
authors.forename: Gökce
authors.initials: G
authors.lastname: Sirin
authors.forename: Lale
authors.initials: L
authors.lastname: Yüceyar
authors.forename: Hasan
authors.initials: H
authors.lastname: Tüzün
authors.forename: Ayla Gürel
authors.initials: AG
authors.lastname: Sayin
mesh_terms: D000293:Adolescent; D000328:Adult; D000671:Amputation, Surgical; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D013562:Sympathectomy / Q000379:methods; D013919:Thromboangiitis Obliterans / Q000601:surgery*; D016896:Treatment Outcome; D014654:Vascular Patency / Q000502:physiology