title: A dose-response study with the feed enzyme beta-mannanase in broilers provided with corn-soybean meal based diets in the absence of antibiotic growth promoters.
abstract: An experiment was designed to assess the effects of graded levels of beta-mannanase on performance and body weight uniformity of male broilers provided with diets based on corn and soybean meal and devoid of antibiotic growth promoters or coccidiostats. Four dietary treatments contained 0, 50, 80, and 110 MU of Hemicell/ ton (where 1 MU = 10(6) enzyme activity units, 100 MU/ton is manufacturer's recommendation). Each treatment contained 15 pens with 40 birds/pen. Individual bird weights were determined on d 0, 21, and 42. From 21 to 42 d of age, feed intake for the 80 MU/ton treatment was significantly greater than the 50 MU/ton treatment. beta-Mannanase inclusion at 80 or 110 MU/ton induced improvements (P < 0.05) in weight gain (3.9 to 4.8%) and feed efficiency (3.5 to 3.8%) over the control, whereas inclusion of 50 MU/ton resulted in no significant benefit. There were no significant differences between 80 or 110 MU/ton. The experiment demonstrated that dietary inclusion of beta-mannanase at approximately 50 MU/ton is not sufficient for maximum response. Inclusion at 80 MU/ ton improved broiler gains and feed conversion and increasing to 110 MU/ton resulted in no significant additional response.
authors.affiliation: ChemGen Corporation, Gaithersburg, Maryland 20877-2144, USA. mjackson@chemgen.com
authors.forename: M E
authors.initials: ME
authors.lastname: Jackson
authors.forename: K
authors.initials: K
authors.lastname: Geronian
authors.forename: A
authors.initials: A
authors.lastname: Knox
authors.forename: J
authors.initials: J
authors.lastname: McNab
authors.forename: E
authors.initials: E
authors.lastname: McCartney
mesh_terms: D000821:Animal Feed; D000818:Animals; D001835:Body Weight / Q000187:drug effects*; D002645:Chickens / Q000254:growth & development*; D004032:Diet; D004305:Dose-Response Relationship, Drug; D005247:Feeding Behavior; D008297:Male; D015430:Weight Gain / Q000187:drug effects; D044902:beta-Mannosidase / Q000008:administration & dosage* / Q000494:pharmacology*
chemical_list: D044902:beta-Mannosidase