title: Pentacyclic triterpenoids from Aster ageratoides var. pilosus.
abstract: Two new pentacyclic triterpenoids, 2beta,3beta,16alpha-trihydroxyl-24alpha-al-olean-12-en-28-oic acid (1), 2beta,3beta-dihydroxyl-16-O-beta-D-glucopyranose-24alpha-al-olean-12-en-28-oic acid (2) and two known pentacyclic triterpenoids were isolated from the roots of Aster ageratoides var. pilosus. Their structures were elucidated by spectroscopic methods (IR, MS, 1H, 13C and 2D NMR). In addition, the anti-bacterial activity and anti-tumor activity of compound 2 were tested.
authors.affiliation: College of Chemistry and Chemical Engineering, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, PR China.
authors.forename: Fu-Lin
authors.initials: FL
authors.lastname: Yan
authors.forename: Ai-Xia
authors.initials: AX
authors.lastname: Wang
authors.forename: Zhong-Jian
authors.initials: ZJ
authors.lastname: Jia
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D031173:Aster Plant / Q000737:chemistry*; D001412:Bacillus subtilis / Q000187:drug effects; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D004926:Escherichia coli / Q000187:drug effects; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D021241:Spectrometry, Mass, Electrospray Ionization; D013211:Staphylococcus aureus / Q000187:drug effects; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D000972:Antineoplastic Agents, Phytogenic; D014315:Triterpenes