Sotalol versus propafenone for long-term maintenance of normal sinus rhythm in patients with recurrent symptomatic atrial fibrillation.
This prospective, randomized, single-blinded, placebo-controlled study compared the efficacy and safety of sotalol and propafenone when used for long-term prevention of atrial fibrillation. For the long-term maintenance of normal sinus rhythm, propafenone seems to be more effective than sotalol.
Kochiadakis
George E
GE
Cardiology Department, University Hospital of Heraklion, Heraklion, Crete, Greece.
Igoumenidis
Nikos E
NE
Hamilos
Michail E
ME
Tzerakis
Panagiotis G
PG
Klapsinos
Nikos C
NC
Chlouverakis
Gregory I
GI
Vardas
Panos E
PE
D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011405:Propafenone / Q000627:therapeutic use*; D011446:Prospective Studies; D012008:Recurrence; D012449:Safety; D013015:Sotalol / Q000627:therapeutic use*
D000889:Anti-Arrhythmia Agents; D011405:Propafenone; D013015:Sotalol