title: GeneNet in 2005.
abstract: The GeneNet system is designed for collection and analysis of the data on gene and metabolic networks, signal transduction pathways and kinetic characteristics of elementary processes. In the past 2 years, the GeneNet structure was considerably improved: (i) the current version of the database is now implemented using ORACLE9i; (ii) the capacities to describe the structure of the protein complexes and the interactions between the units are increased; (iii) two tables with kinetic constants and more detailed descriptions of certain reactions were added; and (iv) a module for kinetic modeling was supplemented. The current SRS release of the GeneNet database contains 37 graphical maps of gene networks, as well as descriptions of 1766 proteins, 1006 genes, 241 small molecules and 3254 relationships between gene network units, and 552 kinetic constants. Information distributed between 16 interlinked tables was obtained by annotating 1980 journal publications. SRS release of the GeneNet database, the graphical viewer and the modeling section are available at http://wwwmgs.bionet.nsc.ru/mgs/gnw/genenet/.
authors.affiliation: Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Lavrentiev Avenue 10, Novosibirsk 630090, Russia. eananko@bionet.nsc.ru
authors.forename: E A
authors.initials: EA
authors.lastname: Ananko
authors.forename: N L
authors.initials: NL
authors.lastname: Podkolodny
authors.forename: I L
authors.initials: IL
authors.lastname: Stepanenko
authors.forename: O A
authors.initials: OA
authors.lastname: Podkolodnaya
authors.forename: D A
authors.initials: DA
authors.lastname: Rasskazov
authors.forename: D S
authors.initials: DS
authors.lastname: Miginsky
authors.forename: V A
authors.initials: VA
authors.lastname: Likhoshvai
authors.forename: A V
authors.initials: AV
authors.lastname: Ratushny
authors.forename: N N
authors.initials: NN
authors.lastname: Podkolodnaya
authors.forename: N A
authors.initials: NA
authors.lastname: Kolchanov
mesh_terms: D003196:Computer Graphics; D003198:Computer Simulation; D030541:Databases, Genetic; D007700:Kinetics; D008660:Metabolism; D008957:Models, Genetic; D046912:Multiprotein Complexes / Q000737:chemistry; D015398:Signal Transduction
chemical_list: D046912:Multiprotein Complexes