title: Synthesis and melanin biosynthesis inhibitory activity of (+/-)-terrein produced by Penicillium sp. 20135.
abstract: Terrein was isolated from Penicillium sp. 20135, prepared by a practical synthetic way, and evaluated first time for its melanin biosynthesis inhibitory activity.
authors.affiliation: Korea Research Institute of Bioscience and Biotechnology, 52 Oun, Yusong, Taejon 305-333, Republic of Korea.
authors.forename: Sangku
authors.initials: S
authors.lastname: Lee
authors.forename: Won-Gon
authors.initials: WG
authors.lastname: Kim
authors.forename: Eungsoo
authors.initials: E
authors.lastname: Kim
authors.forename: In-Ja
authors.initials: IJ
authors.lastname: Ryoo
authors.forename: Hyeong Kyu
authors.initials: HK
authors.lastname: Lee
authors.forename: Jae Nyoung
authors.initials: JN
authors.lastname: Kim
authors.forename: Sang-Hun
authors.initials: SH
authors.lastname: Jung
authors.forename: Ick-Dong
authors.initials: ID
authors.lastname: Yoo
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D008543:Melanins / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D008544:Melanocytes / Q000187:drug effects*; D008956:Models, Chemical; D010407:Penicillium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000900:Anti-Bacterial Agents; D003517:Cyclopentanes; D004791:Enzyme Inhibitors; D008543:Melanins; C439087:terrein