title: Relationship between anxiety and thyroid function in patients with panic disorder.
abstract: The aim of this study was to investigate correlations between thyroid function and severity of anxiety or panic attacks in patients with panic disorder. The authors examined 66 out-patients with panic disorder (medicated, n=41; non-medicated, n=25), and measured their free thriiodothyronine (T3), free thyroxine (T4) and thyroid-stimulating hormone (TSH) levels. Significant correlations between the thyroid hormone levels and clinical features were observed in the non-medicated patients. The more severe current panic attacks were, the higher the TSH levels were. In addition, severity of anxiety correlated negatively with free T4 levels. In this study, we discuss relationship between thyroid function and the clinical severity or features of panic disorder.
authors.affiliation: Department of Psychiatry and Neurobiology, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa 920-8641, Japan. mitsuru@zc4.so-net.ne.jp
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Kikuchi
authors.forename: Ryutarou
authors.initials: R
authors.lastname: Komuro
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Oka
authors.forename: Tomokazu
authors.initials: T
authors.lastname: Kidani
authors.forename: Akira
authors.initials: A
authors.lastname: Hanaoka
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Koshino
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000379:Agoraphobia / Q000097:blood / Q000523:psychology; D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D001007:Anxiety / Q000503:physiopathology* / Q000523:psychology*; D001341:Autonomic Nervous System / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016584:Panic Disorder / Q000188:drug therapy / Q000503:physiopathology* / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D013960:Thyroid Function Tests; D013963:Thyroid Hormones / Q000097:blood
chemical_list: D000928:Antidepressive Agents; D013963:Thyroid Hormones