title: Nasojejunal tube placement after total gastrectomy: a multicenter prospective randomized trial.
abstract: OBJECTIVE
  Anastomotic disruption of the Roux-en-Y esophagojejunostomy after total gastrectomy is an infrequent complication that may lead to severe morbidity and mortality. Consequently, a nasojejunal tube (NJT) is frequently placed when this operation is performed. However, no studies have compared routine vs no placement of an NJT in patients undergoing total gastrectomy for gastric cancer, to our knowledge.
  
  
  METHODS
  Randomized controlled trial to assess the need for routine nasojejunal decompression after total gastrectomy with Roux-en-Y esophagojejunostomy in patients with gastric cancer.
  
  
  METHODS
  Tertiary care centers.
  
  
  METHODS
  Two hundred thirty-seven patients undergoing total gastrectomy for gastric cancer were randomly assigned to NJT placement (NJT group) or not (no-NJT group). The patients were monitored for postoperative complications, mortality, and postoperative course.
  
  
  METHODS
  Incidence of esophagojejunostomy leak.
  
  
  RESULTS
  The rates of anastomotic leak were similar in both groups (6.9% and 5.8% for the NJT group and no-NJT group, respectively; P = .71), as were the rates of major postoperative complications (25.9% and 21.5%, respectively; P = .42) and overall postoperative mortality (0.9% and 0.8%, respectively; P = .50). There were no differences between the 2 groups in the mean+/-SD time to passage of flatus (4.6 +/- 1.3 and 4.5 +/- 1.7 days, respectively) or to starting a liquid diet (7.8 +/- 2.6 and 7.7 +/- 1.6 days, respectively), postoperative length of hospital stay (13.5 +/- 7.3 and 13.9 +/- 10.9 days, respectively), postoperative pain, or postoperative abdominal distention.
  
  
  CONCLUSIONS
  Routine placement of an NJT after Roux-en-Y esophagojejunostomy is unnecessary in elective total gastrectomy for gastric cancer.
authors.affiliation: Digestive Surgery Unit, Department of Surgical Sciences, Catholic University School of Medicine, Rome, Italy.
authors.forename: Giovanni Battista
authors.initials: GB
authors.lastname: Doglietto
authors.forename: Valerio
authors.initials: V
authors.lastname: Papa
authors.forename: Antonio Pio
authors.initials: AP
authors.lastname: Tortorelli
authors.forename: Maurizio
authors.initials: M
authors.lastname: Bossola
authors.forename: Marcello
authors.initials: M
authors.lastname: Covino
authors.forename: Fabio
authors.initials: F
authors.lastname: Pacelli
mesh_terms: D000713:Anastomosis, Roux-en-Y; D004947:Esophagus / Q000601:surgery; D005260:Female; D005743:Gastrectomy; D006801:Humans; D007440:Intubation; D007583:Jejunum / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011183:Postoperative Complications / Q000628:therapy; D013274:Stomach Neoplasms / Q000601:surgery