Gold and silver nanoparticles functionalized with known numbers of oligonucleotides per particle for DNA detection.
The biospecificity of gold and silver nanoparticles, functionalized with known numbers of oligonucleotides, is demonstrated in colorimetric microbead assays for complementary and mismatch sequences.
Chen
Yang
Y
Department of Chemistry and Centre for Bioarray Innovation, Liverpool University, Liverpool, UK L69 7ZD.
Aveyard
Jenny
J
Wilson
Robert
R
D001483:Base Sequence; D003124:Colorimetry / Q000379:methods*; D004247:DNA / Q000032:analysis* / Q000235:genetics*; D006046:Gold / Q000737:chemistry*; D008863:Microspheres; D049329:Nanostructures / Q000737:chemistry*; D009841:Oligonucleotides / Q000737:chemistry* / Q000235:genetics; D012834:Silver / Q000737:chemistry*; D013057:Spectrum Analysis
D009841:Oligonucleotides; D012834:Silver; D006046:Gold; D004247:DNA