title: Intravascular ultrasonic comparative analysis of degree of intimal hyperplasia produced by four different stents in the coronary arteries.
abstract: Intravascular ultrasound studies were performed at angiographic follow-up on 121 native coronary lesions treated with 1 bare metal stent (n = 50), high-dose dexamethasone-eluting stents (n = 18), non-polymer-based paclitaxel-eluting stents (n = 18), or sirolimus-eluting stents (n = 35). Paclitaxel- and sirolimus-eluting stents reduced mean intimal hyperplasia thickness compared with bare metal stents by 49% and 90% (p = 0.048 and p <0.001), respectively, whereas mean intimal hyperplasia thickness treated with dexamethasone-eluting stents was similar to those lesions treated with bare metal stents.
authors.affiliation: Medical Clinic I, University RWTH Aachen, Aachen, Germany. RHoffmann@UKAACHEN.de
authors.forename: Rainer
authors.initials: R
authors.lastname: Hoffmann
authors.forename: Peter W
authors.initials: PW
authors.lastname: Radke
authors.forename: Jan R
authors.initials: JR
authors.lastname: Ortlepp
authors.forename: Philipp K
authors.initials: PK
authors.lastname: Haager
authors.forename: Rüdiger
authors.initials: R
authors.lastname: Blindt
authors.forename: Ekatarina
authors.initials: E
authors.lastname: Iofina
authors.forename: Andreas
authors.initials: A
authors.lastname: Franke
authors.forename: Roswitha
authors.initials: R
authors.lastname: Langenberg
authors.forename: Christian
authors.initials: C
authors.lastname: Weber
authors.forename: Peter
authors.initials: P
authors.lastname: Hanrath
mesh_terms: D023903:Coronary Restenosis / Q000209:etiology; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000473:pathology*; D003907:Dexamethasone; D006801:Humans; D006965:Hyperplasia; D017239:Paclitaxel; D011474:Prosthesis Design; D020123:Sirolimus; D015607:Stents / Q000009:adverse effects; D017539:Tunica Intima / Q000473:pathology; D018084:Ultrasonography, Interventional
chemical_list: D003907:Dexamethasone; D017239:Paclitaxel; D020123:Sirolimus