A case of epidermal cyst with pilomatrical differentiation.
A 20-year-old Japanese woman with an epidermal cyst on the back is described. Physical examination revealed a deep blue and round shaped cystic lesion measuring 10 min in diameter. A comedo-like keratotic plug also could be seen at the center. Histologically, the inner surface of the cyst was clearly separated of two types of the cells. The one was layers of epidermal keratinocytes and the other looked like a basal layer of epidermis, which immunohistochemically stained by S-100, HMB-45, cytokeratin (CK19) and Fontana-Masson staining. We diagnosed this case as epidermal cyst with pilomatrical differentiation.
Ikoma
Norihiro
N
Department of Dermatology, Tokai University School of Medicine, Kanagawa, Japan.
Iwashita
Kenichi
K
Umezawa
Yoshinori
Y
Matsuyama
Takashi
T
Ohta
Yukinori
Y
Ozawa
Akira
A
Umemura
Shinobu
S
Ueyama
Yoshito
Y
Yamazaki
Hitoshi
H
D000328:Adult; D002454:Cell Differentiation; D004814:Epidermal Cyst / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D004817:Epidermis / Q000378:metabolism / Q000473:pathology; D005260:Female; D018859:Hair Follicle / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D015603:Keratinocytes / Q000166:cytology; D007633:Keratins / Q000378:metabolism; D009418:S100 Proteins / Q000378:metabolism; D012835:Silver Nitrate; D012871:Skin Diseases / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D013194:Staining and Labeling; D016896:Treatment Outcome
C051037:Fontana-Masson stain; D009418:S100 Proteins; D007633:Keratins; D012835:Silver Nitrate