title: Acute pulmonary edema caused by hypoglycemia due to insulin overdose.
abstract: We report a very rare case of acute pulmonary edema caused by hypoglycemia from insulin overdose during an attempted suicide. A 16-year-old woman with type 1 diabetes was brought to our hospital because of hypoglycemic coma. She exhibited severe hypoxia; upon intubation, bloody froth poured out of the tube. Chest X-ray revealed bilateral infiltrates. Endocrinological data revealed high concentrations of catecholamines. This case indicates that pulmonary edema remains a potential complication of insulin overdose. The possible mechanisms of pulmonary edema associated with hypoglycemia are discussed.
authors.affiliation: Department of Endocrinology and Metabolism, Kimitsu Central Hospital, Chiba.
authors.forename: Daigaku
authors.initials: D
authors.lastname: Uchida
authors.forename: Sawako
authors.initials: S
authors.lastname: Ohigashi
authors.forename: Satosi
authors.initials: S
authors.lastname: Hikita
authors.forename: Nobuya
authors.initials: N
authors.lastname: Kitamura
authors.forename: Mitsutaka
authors.initials: M
authors.lastname: Motoyoshi
authors.forename: Ichiro
authors.initials: I
authors.lastname: Tatsuno
mesh_terms: D000293:Adolescent; D001774:Blood Chemical Analysis; D062787:Drug Overdose / Q000150:complications; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced*; D007004:Hypoglycemic Agents / Q000009:adverse effects*; D007328:Insulin / Q000009:adverse effects*; D011654:Pulmonary Edema / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D013902:Radiography, Thoracic; D012121:Respiration, Artificial / Q000379:methods
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin