Longterm follow-up of patients with multifocal choroiditis and panuveitis.
OBJECTIVE
To report the visual prognosis and longterm complications in patients with multifocal choroiditis and panuveitis (MCP).


METHODS
A retrospective study was performed with patients who met inclusion criteria for MCP at the Uveitis Clinic, Royal Victoria Hospital, McGill University, Montreal, Canada. Information collected included duration of follow-up, visual acuity (VA) measured at each clinical visit, ocular and systemic treatment and ocular complications observed during follow-up.


RESULTS
Nineteen patients (37 eyes) with MCP with a mean follow-up of 76.9 months were studied. Kaplan-Meier survival analysis showed a decrease in the proportion of patients with a final VA > or = 20/40 over time. Cystoid macular oedema was seen in 29.7% of the eyes and was the most frequent macular abnormality observed in our group. On the other hand, choroidal neovascularization was detected in only six (16.2%) of the eyes, but was related to VA < 20/200 in four of these eyes. Glaucoma was detected in 10.8% of the eyes. Cataract (posterior subcapsular and/or nuclear) was the most common longterm complication, occurring in 40% of affected eyes. Cataract surgery improved the VA in 83.3% of these eyes.


CONCLUSIONS
The visual acuity of patients with MCP decreases with time. Visual loss can occur from complications following the inflammation itself and/or iatrogenic induced by the chronic use of corticosteroids.
Vianna
Raul N G
RN
Uveitis and Ocular Immunology Unit, Department of Ophthalmology, Royal Victoria Hospital, McGill University Health Center, Montreal, Quebec, Canada. raulngvianna@ig.com.br
Ozdal
Pinar C
PC
Filho
João Pessoa Souza
JP
Ventura
Marcelo Palis
MP
Saraiva
Vinicius S
VS
Deschênes
Jean
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002833:Choroiditis / Q000150:complications*; D005128:Eye Diseases / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015864:Panuveitis / Q000150:complications*; D011379:Prognosis; D012189:Retrospective Studies; D014786:Vision Disorders / Q000209:etiology; D014792:Visual Acuity