Transient swelling of peripheral nerves in a case of neurosarcoidosis.
We present a case of neurosarcoidosis showing bilateral carpal tunnel syndrome which disappeared without any medication. This patient was also suffering from motor and sensory disturbance caused by peripheral neuropathy of the four extremities. Magnetic resonance image showed transient swelling of the median nerve, and subperineurial edema was unexpectedly observed in some fascicles in sural nerve biopsy. We hypothesize that the carpal tunnel syndrome in this case was induced by the intercanal high pressure due to edema inside the tunnel, which might be related to the high level of serum IL-2.
Nakatani-Enomoto
Setsu
S
First Department of Internal Medicine, Section of Neurology, Asahikawa Medical College, Asahikawa.
Aizawa
Hitoshi
H
Koyama
Satoshi
S
Kuroda
Kenji
K
Kimura
Takashi
T
Kikuchi
Kenjiro
K
D000368:Aged; D002349:Carpal Tunnel Syndrome / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D010525:Peripheral Nerves / Q000473:pathology; D011115:Polyneuropathies / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D012507:Sarcoidosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D016896:Treatment Outcome
D005938:Glucocorticoids