title: Long-term effects of green tea ingestion on atherosclerotic biological markers in smokers.
abstract: OBJECTIVE
  Smoking is a risk factor for coronary artery disease and triggers vascular injury by platelet aggregation and induces atherosclerosis through induction of oxidative stress. Green tea is known to have antioxidant capacity and anti-platelet activity.
  
  
  METHODS
  Twenty adult male smokers ingested 600 mL of green tea for 4 weeks. Their lipid profile, C-reactive protein (CRP), total antioxidant capacity, oxidized LDL, soluble VCAM-1, soluble ICAM-1, and soluble P-selectin were measured at baseline and 2 and 4 weeks after green tea ingestion.
  
  
  RESULTS
  Plasma soluble P-selectin (sP-selectin) levels decreased significantly after 2 and 4 weeks of green tea ingestion compared with those before green tea ingestion (P < 0.001). Plasma concentrations of oxidized LDL decreased significantly after green tea ingestion (P < 0.05).
  
  
  CONCLUSIONS
  The results of this study suggest the effect of green tea on sP-selectin and oxidized LDL.
authors.affiliation: Department of Laboratory Medicine, Asan Medical Center and University of Ulsan College of Medicine, Songpa-Gu, Seoul, South Korea.
authors.forename: Woochang
authors.initials: W
authors.lastname: Lee
authors.forename: Won-Ki
authors.initials: WK
authors.lastname: Min
authors.forename: Sail
authors.initials: S
authors.lastname: Chun
authors.forename: Yong-Wha
authors.initials: YW
authors.lastname: Lee
authors.forename: Hyosoon
authors.initials: H
authors.lastname: Park
authors.forename: Do Hoon
authors.initials: DH
authors.lastname: Lee
authors.forename: You Kyoung
authors.initials: YK
authors.lastname: Lee
authors.forename: Ji Eun
authors.initials: JE
authors.lastname: Son
mesh_terms: D000328:Adult; D001161:Arteriosclerosis / Q000378:metabolism*; D015415:Biomarkers; D006801:Humans; D008077:Lipoproteins, LDL / Q000097:blood; D019007:P-Selectin / Q000097:blood; D012907:Smoking / Q000378:metabolism*; D013662:Tea / Q000378:metabolism*; D013997:Time Factors
chemical_list: D015415:Biomarkers; D008077:Lipoproteins, LDL; D019007:P-Selectin; D013662:Tea; C099252:oxidized low density lipoprotein