[Methods for single unit recording in behavioring morphine craving rat].
In this paper, one method was introduced, which was a combination of the cue-related morphine addiction model and a technique for obtaining chronic extracellular recordings of single unit in freely moving rats. With the combination and improvement of this technique, we have successfully applied this new method to study the neuronal activity of the hippocampus CA1 region in morphine withdrawal rats. In all, we found some more accurate and objective cellular characteristics of hippocampal neurons, and considered these characteristics as one of electrophysiological indexes of morphine addiction rats.
Liu
Su-Qing
SQ
Section of Primates Cognitive Brain Research, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming 650223, China.
Wu
Jing
J
Yang
Jian-Zhen
JZ
Tian
Shao-Hua
SH
Chen
Nan-Hui
NH
Lei
Yan-Lin
YL
Peng
Yan-Ping
YP
Wang
Jian-Hong
JH
Ma
Yuan-Ye
YY
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D004594:Electrophysiology / Q000295:instrumentation*; D006624:Hippocampus / Q000503:physiopathology*; D009021:Morphine Dependence / Q000503:physiopathology* / Q000523:psychology*; D009474:Neurons / Q000502:physiology; D051381:Rats; D013375:Substance Withdrawal Syndrome / Q000503:physiopathology* / Q000523:psychology