title: Efficient antioxidant capacity against lipid peroxide levels in healthy elderly of Mexico City.
abstract: We evaluated antioxidant activity against lipid peroxide levels (LPO) in healthy elderly and adults of Mexico City in comparison with a population of a rural area. The study included free-living subjects: 38 adults aged <60 years and 129 older subjects aged > or = 60 years of urban Mexico City in addition to 37 adults aged <60 years and 88 older subjects aged > or = 60 years of rural area (Actopan, Hidalgo State, Mexico). LPO were observed as higher in adults and elderly of the urban area than among rural subjects (P<0.01), although LPO levels were similar in rural adults and elderly (P>0.05); conversely, in urban area levels were higher in the elderly than in adults (P<0.01). On the other hand, the superoxide dismutase in urban elderly was higher than that in rural elderly (P<0.05) but similar between urban adults and urban elderly (P>0.05). Total oxidant status in urban elderly was higher than that in rural elderly (P<0.01). Our findings allow us to conclude that the urban elderly (residents of Mexico City) have higher oxidative stress than the rural-dwelling elderly, though the urban elderly have efficient antioxidant capacity as a response to elevated LPO.
authors.affiliation: Unidad de Investigación en Gerontología, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Fuerte de Loreto, Col. Ejercito de Oriente, Batalla 5 de mayo s/n, esq. 09230 Mexico City, Mexico.
authors.forename: Martha A
authors.initials: MA
authors.lastname: Sánchez-Rodríguez
authors.forename: Raquel
authors.initials: R
authors.lastname: Retana-Ugalde
authors.forename: Mirna
authors.initials: M
authors.lastname: Ruíz-Ramos
authors.forename: José Luis
authors.initials: JL
authors.lastname: Muñoz-Sánchez
authors.forename: Luis Alberto
authors.initials: LA
authors.lastname: Vargas-Guadarrama
authors.forename: Víctor Manuel
authors.initials: VM
authors.lastname: Mendoza-Núñez
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000397:Air Pollution; D000975:Antioxidants / Q000032:analysis* / Q000378:metabolism; D004781:Environmental Exposure / Q000706:statistics & numerical data*; D005260:Female; D006299:Health Services for the Aged; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood*; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D018384:Oxidative Stress; D012307:Risk Factors; D012423:Rural Health; D014504:Urban Health
chemical_list: D000975:Antioxidants; D008054:Lipid Peroxides