title: Combining two-directional synthesis and tandem reactions: an efficient strategy for the total syntheses of (+/-)-hippodamine and (+/-)-epi-hippodamine.
abstract: Two-directional total stereoselective syntheses of (+/-)-hippodamine and (+/-)-epi-hippodamine, utilising a tandem deprotection/intramolecular double Michael addition sequence as the key step, are presented.
authors.affiliation: School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich, UK NR4 7TJ.
authors.forename: Martin
authors.initials: M
authors.lastname: Rejzek
authors.forename: Robert A
authors.initials: RA
authors.lastname: Stockman
authors.forename: David L
authors.initials: DL
authors.lastname: Hughes
mesh_terms: D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D011799:Quinazolines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000588:Amines; D011799:Quinazolines; C511678:hippodamine