Hepatoblastoma in a patient with a partial trisomy 9p syndrome: a case report.
After an uneventful pregnancy, a boy was born by vacuum extraction at 40.6 weeks' gestation. Physical examination revealed several malformations due to a partial trisomy 9p [karyotype: 46,XY, dup(9)(p13p24)]. Three months after birth, the boy presented with a hepatoblastoma without distant metastases which was treated with chemotherapy combined with surgery. At the last follow-up, 15 years after the resection of the hepatoblastoma, he was still in complete remission. To our knowledge this is the first case report of a patient with a constitutional partial trisomy 9p associated with hepatoblastoma.
Schnater
J Marco
JM
Pediatric Surgical Center of Amsterdam (Emma Children's Hospital AMC / Vrije Universiteit Medical Center), Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Schouten-van Meeteren
Antoinette Y N
AY
Heins
Yvonne M
YM
Aronson
Daniël C
DC
D000015:Abnormalities, Multiple / Q000235:genetics*; D002899:Chromosomes, Human, Pair 9; D018197:Hepatoblastoma / Q000150:complications*; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000150:complications*; D008297:Male; D014314:Trisomy / Q000235:genetics*