title: Synthesis of zwitterionic 4-hydroxycoumarin derivatives through a unique reaction of 4-hydroxycoumarins with p- benzoquinone and pyridine.
abstract: [reaction: see text] A unique reaction of 4-hydroxycoumarins with p-benzoquinone and pyridine was found, and through the reaction, six zwitterionic 4-hydroxycoumarin derivatives were synthesized. The structures of these compounds were determined by IR, MS(ESI), 1H NMR, 13C NMR, and single-crystal X-ray diffraction studies.
authors.affiliation: School of Pharmaceutical Science, Sun Yat-Sen University, Guangzhou, 510275 People's Republic of China.
authors.forename: Sheng-Ling
authors.initials: SL
authors.lastname: Zhang
authors.forename: Zhi-Shu
authors.initials: ZS
authors.lastname: Huang
authors.forename: Lin-Kun
authors.initials: LK
authors.lastname: An
authors.forename: Xian-Zhang
authors.initials: XZ
authors.lastname: Bu
authors.forename: Lin
authors.initials: L
authors.lastname: Ma
authors.forename: Yue-Ming
authors.initials: YM
authors.lastname: Li
authors.forename: Albert S C
authors.initials: AS
authors.lastname: Chan
authors.forename: Lian-Quan
authors.initials: LQ
authors.lastname: Gu
mesh_terms: D015110:4-Hydroxycoumarins / Q000138:chemical synthesis* / Q000737:chemistry*; D016227:Benzoquinones / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods / Q000592:standards; D008958:Models, Molecular; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*; D012015:Reference Standards; D012680:Sensitivity and Specificity; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods; D013055:Spectrophotometry, Infrared / Q000379:methods; D013237:Stereoisomerism; D014961:X-Ray Diffraction
chemical_list: D015110:4-Hydroxycoumarins; D016227:Benzoquinones; D011725:Pyridines; C023666:pyridine