title: Quassinoids can induce mitochondrial membrane depolarisation and caspase 3 activation in human cells.
authors.forename: A
authors.initials: A
authors.lastname: Rosati
authors.forename: E
authors.initials: E
authors.lastname: Quaranta
authors.forename: M
authors.initials: M
authors.lastname: Ammirante
authors.forename: M C
authors.initials: MC
authors.lastname: Turco
authors.forename: A
authors.initials: A
authors.lastname: Leone
authors.forename: V
authors.initials: V
authors.lastname: De Feo
mesh_terms: D032268:Ailanthus / Q000737:chemistry; D017209:Apoptosis / Q000187:drug effects; D051017:Apoptosis Regulatory Proteins; D053148:Caspase 3; D020169:Caspases / Q000187:drug effects* / Q000378:metabolism; D045744:Cell Line, Tumor; D004789:Enzyme Activation / Q000187:drug effects; D006801:Humans; D019169:Jurkat Cells / Q000187:drug effects*; D008562:Membrane Glycoproteins / Q000494:pharmacology; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D008928:Mitochondria / Q000187:drug effects* / Q000378:metabolism; D036702:Quassins / Q000302:isolation & purification / Q000494:pharmacology*; D011994:Recombinant Proteins / Q000494:pharmacology; D053221:TNF-Related Apoptosis-Inducing Ligand; D013997:Time Factors; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology
chemical_list: D051017:Apoptosis Regulatory Proteins; D008562:Membrane Glycoproteins; D036702:Quassins; D011994:Recombinant Proteins; D053221:TNF-Related Apoptosis-Inducing Ligand; C505653:TNFSF10 protein, human; D014409:Tumor Necrosis Factor-alpha; C029825:ailanthone; C505407:CASP3 protein, human; D053148:Caspase 3; D020169:Caspases