Genetic cancer risk assessment and counseling: recommendations of the national society of genetic counselors.
These cancer genetic counseling recommendations describe the medical, psychosocial, and ethical ramifications of identifying at-risk individuals through cancer risk assessment with or without genetic testing. They were developed by members of the Practice Issues Subcommittee of the National Society of Genetic Counselors Cancer Genetic Counseling Special Interest Group. The information contained in this document is derived from extensive review of the current literature on cancer genetic risk assessment and counseling as well as the personal expertise of genetic counselors specializing in cancer genetics. The recommendations are intended to provide information about the process of genetic counseling and risk assessment for hereditary cancer disorders rather than specific information about individual syndromes. Key components include the intake (medical and family histories), psychosocial assessment (assessment of risk perception), cancer risk assessment (determination and communication of risk), molecular testing for hereditary cancer syndromes (regulations, informed consent, and counseling process), and follow-up considerations. These recommendations should not be construed as dictating an exclusive course of management, nor does use of such recommendations guarantee a particular outcome. These recommendations do not displace a health care provider's professional judgment based on the clinical circumstances of a client.
Trepanier
Angela
A
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Wayne State University, Detroit, Michigan, USA.
Ahrens
Mary
M
McKinnon
Wendy
W
Peters
June
J
Stopfer
Jill
J
Grumet
Sherry Campbell
SC
Manley
Susan
S
Culver
Julie O
JO
Acton
Ronald
R
Larsen-Haidle
Joy
J
Correia
Lori Ann
LA
Bennett
Robin
R
Pettersen
Barbara
B
Ferlita
Terri Diamond
TD
Costalas
Josephine Wagner
JW
Hunt
Katherine
K
Donlon
Susan
S
Skrzynia
Cecile
C
Farrell
Carolyn
C
Callif-Daley
Faith
F
Vockley
Catherine Walsh
CW
D019091:Critical Pathways; D005817:Genetic Counseling / Q000379:methods; D005820:Genetic Testing; D006801:Humans; D008487:Medical History Taking; D025202:Molecular Diagnostic Techniques; D009154:Mutation / Q000235:genetics; D009369:Neoplasms / Q000175:diagnosis / Q000235:genetics*; D009386:Neoplastic Syndromes, Hereditary / Q000175:diagnosis / Q000235:genetics*; D018570:Risk Assessment