Saccharomyces cerevisiae fungemia in an elderly patient with Clostridium difficile colitis.
Saccharomyces boulardii is widely used as a probiotic compound and is generally thought to be safe. We report one case of fungemia caused by Saccharomyces cerevisiae occurring in an elderly patient treated orally with S. boulardii in association with vancomycin for Clostridium difficile colitis. We do not recommend administering this viable yeast particularly in debilited patient with active colitis.
Cherifi
S
S
Department of Internal Medicine, Brugmann Hospital, Free Brussels University, Belgium. sorayalaure.cherifi@chu-brugmann.be
Robberecht
J
J
Miendje
Y
Y
D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D016360:Clostridioides difficile / Q000187:drug effects / Q000302:isolation & purification*; D004359:Drug Therapy, Combination; D004761:Enterocolitis, Pseudomembranous / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D005500:Follow-Up Studies; D016469:Fungemia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D019936:Probiotics / Q000009:adverse effects*; D018570:Risk Assessment; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000302:isolation & purification*; D016896:Treatment Outcome; D014640:Vancomycin / Q000627:therapeutic use; D015002:Yeast, Dried / Q000627:therapeutic use
C009786:perenterol; D014640:Vancomycin