title: Isochromosome 20p associated with multiple congenital abnormalities.
abstract: A second case of tetrasomy 20p due to an additional isochromosome 20p is reported. This resulted in a spontaneous intrauterine death with multiple congenital abnormalities. In keeping with the previous report, the foetus had poor ossification resulting in multiple long bone fractures.
authors.affiliation: Departments of Clinical Genetics Pathology Radiology, Royal Liverpool Children's Hospital Department of Obstetrics, Countess of Chester Hospital Department of Cytogenetics, Liverpool Women's Hospital.
authors.forename: Alan E
authors.initials: AE
authors.lastname: Fryer
authors.forename: Michael
authors.initials: M
authors.lastname: Ashworth
authors.forename: Jed
authors.initials: J
authors.lastname: Hawe
authors.forename: David
authors.initials: D
authors.lastname: Pilling
authors.forename: Margaret
authors.initials: M
authors.lastname: Pauling
authors.forename: Una
authors.initials: U
authors.lastname: Maye
mesh_terms: D002869:Chromosome Aberrations; D002890:Chromosomes, Human, Pair 20; D005260:Female; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D011256:Pregnancy Outcome