Usefulness of single-bolus adenosine test for confirming sinus node dysfunction and correlation with atrial overdrive suppression test.
We prospectively studied 42 consecutive patients who had symptomatic sinus node dysfunction and 17 age-matched controls by measuring maximal and corrected maximal sinus node recovery times with an atrial overdrive suppression test and single-bolus adenosine administration (0.15 mg/kg). We found a positive correlation between the 2 methods, with reasonably good sensitivity, specificity, and predictive accuracy.
Lin
Jih-Min
JM
Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Lin
Jiunn-Lee
JL
Lai
Ling-Ping
LP
Huang
Shoei K Stephen
SK
D000241:Adenosine / Q000008:administration & dosage; D000368:Aged; D001146:Arrhythmia, Sinus / Q000175:diagnosis*; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012680:Sensitivity and Specificity
D000241:Adenosine