title: Panton-Valentine leukocidin positive MRSA in 2003: the Dutch situation.
abstract: Analysis of methicillin-resistant Staphylococcus aureus (MRSA) isolates in the Netherlands in 2003 revealed that 8% of the hospital isolates carried the loci for Panton-Valentine leukocidin (PVL). Molecular subtyping showed that most Dutch PVL-MRSA genotypes corresponded to well-documented global epidemic types. The most common PVL-MRSA genotypes were sequence type ST8, ST22, ST30, ST59 and ST80. MRSA with ST8 increased in the Netherlands from 1% in 2002 to 17% in 2003. It is emphasised that PVL-MRSA might not only emerge in the community, but also in the hospital environment.
authors.affiliation: National Institute of Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
authors.forename: W J B
authors.initials: WJ
authors.lastname: Wannet
authors.forename: M E O C
authors.initials: ME
authors.lastname: Heck
authors.forename: G N
authors.initials: GN
authors.lastname: Pluister
authors.forename: E
authors.initials: E
authors.lastname: Spalburg
authors.forename: M G
authors.initials: MG
authors.lastname: van Santen
authors.forename: X W
authors.initials: XW
authors.lastname: Huijsdans
authors.forename: E
authors.initials: E
authors.lastname: Tiemersma
authors.forename: A J
authors.initials: AJ
authors.lastname: de Neeling
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001427:Bacterial Toxins; D002648:Child; D002675:Child, Preschool; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology; D005098:Exotoxins; D005260:Female; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007956:Leukocidins; D008297:Male; D016106:Methicillin Resistance; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin