title: [Isolation of cobalt-resistant strains of propionic acid bacteria, potent producers of vitamin B12].
abstract: A method of adaptation to cobalt nitrate at high concentrations allowed us to isolate 46 strains of propionic acid bacteria Propionibacterium acidipropionici, resistant to excessive amounts of Co2+ in the medium. Studies of these strains revealed cultures that were most potent in synthesizing vitamin B12. The yield of vitamin B12 was increased 3 times, compared to parent strains.
authors.forename: E A
authors.initials: EA
authors.lastname: Seĭdametova
authors.forename: M R
authors.initials: MR
authors.lastname: Shakirzianova
authors.forename: D M
authors.initials: DM
authors.lastname: Ruzieva
authors.forename: T G
authors.initials: TG
authors.lastname: Guliamova
mesh_terms: D003035:Cobalt / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D011424:Propionibacterium / Q000187:drug effects / Q000302:isolation & purification* / Q000378:metabolism; D014805:Vitamin B 12 / Q000096:biosynthesis*
chemical_list: D003035:Cobalt; C025913:cobaltous nitrate; D014805:Vitamin B 12