Synthesis and melanin biosynthesis inhibitory activity of (+/-)-terrein produced by Penicillium sp. 20135.
Terrein was isolated from Penicillium sp. 20135, prepared by a practical synthetic way, and evaluated first time for its melanin biosynthesis inhibitory activity.
Lee
Sangku
S
Korea Research Institute of Bioscience and Biotechnology, 52 Oun, Yusong, Taejon 305-333, Republic of Korea.
Kim
Won-Gon
WG
Kim
Eungsoo
E
Ryoo
In-Ja
IJ
Lee
Hyeong Kyu
HK
Kim
Jae Nyoung
JN
Jung
Sang-Hun
SH
Yoo
Ick-Dong
ID
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D008543:Melanins / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D008544:Melanocytes / Q000187:drug effects*; D008956:Models, Chemical; D010407:Penicillium / Q000737:chemistry*; D013237:Stereoisomerism
D000900:Anti-Bacterial Agents; D003517:Cyclopentanes; D004791:Enzyme Inhibitors; D008543:Melanins; C439087:terrein