title: PFD: a database for the investigation of protein folding kinetics and stability.
abstract: We have developed a new database that collects all protein folding data into a single, easily accessible public resource. The Protein Folding Database (PFD) contains annotated structural, methodological, kinetic and thermodynamic data for more than 50 proteins, from 39 families. A user-friendly web interface has been developed that allows powerful searching, browsing and information retrieval, whilst providing links to other protein databases. The database structure allows visualization of folding data in a useful and novel way, with a long-term aim of facilitating data mining and bioinformatics approaches. PFD can be accessed freely at http://pfd.med.monash.edu.au.
authors.affiliation: The Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Faculty of Medicine, PO Box 53, Monash University, Clayton, Victoria 3800, Australia.
authors.forename: Kate F
authors.initials: KF
authors.lastname: Fulton
authors.forename: Glyn L
authors.initials: GL
authors.lastname: Devlin
authors.forename: Rachel A
authors.initials: RA
authors.lastname: Jodun
authors.forename: Linda
authors.initials: L
authors.lastname: Silvestri
authors.forename: Stephen P
authors.initials: SP
authors.lastname: Bottomley
authors.forename: Alan R
authors.initials: AR
authors.lastname: Fersht
authors.forename: Ashley M
authors.initials: AM
authors.lastname: Buckle
mesh_terms: D030562:Databases, Protein; D020407:Internet; D007700:Kinetics; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry; D014584:User-Computer Interface
chemical_list: D011506:Proteins