title: Cytogenetics of a pediatric unclassified sex cord-stromal tumor of the testis: a case report.
abstract: Unclassified sex cord-stromal tumors account for a small proportion of pediatric testicular tumors and, while most are clinically benign, some have demonstrated malignant potential. Histological findings do not correlate well with clinical behavior and, while cytogenetics may aid in both diagnosis and predicting clinical behavior, these data on sex cord-stromal tumors are scarce. We describe an unclassified sex cord-stromal tumor occurring in the testis of a prepubertal male without evidence of metastasis that had a previously unreported 54,XY,+3,+7,+9,+12,+13,+18,+19,+20 karyotype.
authors.affiliation: Department of Pathology,University of Utah Health Sciences Center, Room A513, 50 North Medical Drive, Salt Lake City, UT 84132, USA. david.yang@hsc.utah.edu
authors.forename: David T
authors.initials: DT
authors.lastname: Yang
authors.forename: Amy
authors.initials: A
authors.lastname: Lowichik
authors.forename: Jige
authors.initials: J
authors.lastname: Chen
authors.forename: Brent W
authors.initials: BW
authors.lastname: Snow
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Ulbright
authors.forename: Zhong
authors.initials: Z
authors.lastname: Chen
mesh_terms: D002881:Chromosomes, Human, Pair 12; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008297:Male; D018312:Sex Cord-Gonadal Stromal Tumors / Q000235:genetics* / Q000473:pathology; D013736:Testicular Neoplasms / Q000235:genetics* / Q000473:pathology; D014314:Trisomy