title: [Study on the anticancer activities (in vivo) of the extract from Citrus reticulata Blanco and its influence on sarcoma-180 cells cycle].
abstract: OBJECTIVE
  To study the anticancer activity of the extract from Citrus reticulata in vivo.
  
  
  METHODS
  Anticancer activities were tested with tumor model in vivo (Sarcoma-180 cells, Heps cells, EAC cells implanted in mice).
  
  
  RESULTS
  The extract from Citrus reticulata showed marked anticancer activities on Sarcoma-180 cells and Heps cells implanted in mice, had no marked anticancer activities on EAC cells implanted in mice and induced apoptosis of Sarcoma-180 cell.
  
  
  CONCLUSIONS
  The extract from Citrus reticulata will have promising prospects as an anticancer Chinese medicine, but further studies will be needed.
authors.affiliation: Jiangsu Provincial Academy of Traditional Chinese Medicine, Nanjing 210028, Jiangsu, China. qshihui@jlonline.com
authors.forename: Shi-hui
authors.initials: SH
authors.lastname: Qian
authors.forename: Yi-xian
authors.initials: YX
authors.lastname: Wang
authors.forename: Nian-yun
authors.initials: NY
authors.lastname: Yang
authors.forename: Li-hong
authors.initials: LH
authors.lastname: Yuan
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy / Q000473:pathology; D002453:Cell Cycle / Q000187:drug effects; D045744:Cell Line, Tumor; D002957:Citrus / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D005638:Fruit / Q000737:chemistry; D008114:Liver Neoplasms, Experimental / Q000188:drug therapy / Q000473:pathology; D008297:Male; D051379:Mice; D009368:Neoplasm Transplantation; D010946:Plants, Medicinal / Q000737:chemistry; D012510:Sarcoma 180 / Q000188:drug therapy / Q000473:pathology*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal