[Research on components of Cornus officinalis extracted by supercritical carbon dioxide].
OBJECTIVE
To study the chemical constituents of Cornus officinalis extracted by supercritical carbon dioxide fluid extraction (SFE).


METHODS
The process was performed at 40 centigrade with pressures of 15 MPa for 2 hours and with CO2 fluid and gas at the flow rate of 22.0 kg x h(-1) and 18.0 kg x h(-1) respectively. The chemical constituents of the SFE extractions were determined by GC-MS.


RESULTS
The total amount of extractable substances or yields by SFE is 2.42% (mass). 31 Chemical constituents were identified and their relative contents were determined by normalization method of area.


CONCLUSIONS
The major components identified in the extractions are 1,2-benzenedicarboxylic acid, butyl 2-methylpropyl ester, isopropyl myristate etc.
Han
Shu-yan
SY
Nanjing University of Traditional Chinese Medicine, Nanjing 210029, Jiangsu, China. shuyanhan@yahoo.com.cn
Pan
Yang
Y
Yang
Guang-ming
GM
Cai
Bao-chang
BC
D002245:Carbon Dioxide; D025924:Chromatography, Supercritical Fluid; D029768:Cornus / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D009226:Myristates / Q000032:analysis*; D019301:Oleic Acid / Q000032:analysis; D010946:Plants, Medicinal / Q000737:chemistry*
D009226:Myristates; C008205:isopropyl myristate; D002245:Carbon Dioxide; D019301:Oleic Acid