title: Carotid surgery following previous carotid endarterectomy is safe and effective.
abstract: With the perceived high risk of repeat carotid surgery, carotid angioplasty and stenting have been advocated recently as the preferred treatment of recurrent carotid disease following carotid endarterectomy. An experience with the operative treatment of recurrent carotid disease to document the risks and benefits of this procedure is presented. A review of a prospectively acquired vascular registry over a 10-year period (Jan. 1990-Jan. 2000) was undertaken to identify patients undergoing repeat carotid surgery following previous carotid endarterectomy. All patients were treated with repeat carotid endarterectomy, carotid interposition graft, or subclavian-carotid bypass. The perioperative stroke and death rate, operative complications, life-table freedom from stroke, and rates of recurrent stenosis were documented. During the study period 56 patients underwent repeat carotid surgery, comprising 6% of all carotid operations during this period. The indication for operation was symptomatic disease recurrence in 41 cases (73%) and asymptomatic recurrent stenosis >/=80% in 15 cases (27%). The average interval from the prior carotid endarterectomy to the repeat operation was 78 months (range 3 weeks-297 months). The operations performed included repeat carotid endarterectomy with patch angioplasty in 31 cases (55%), interposition grafts in 19 cases (34%), and subclavian-carotid bypass in 6 cases (11%). There were three perioperative strokes with one resulting in death for a perioperative stroke and death rate of 5.4%. One minor transient cranial nerve (CN IX) injury occurred. Mean follow-up was 29 months (range, 1-116 months). Life-table freedom from stroke was 95% at 1 year and 90% at 5 years. Recurrent stenosis (>/=80%) developed in three patients (5.4%) during follow-up, including one internal carotid artery occlusion. Two patients (3.6%) underwent repeat surgery. Repeat surgery for recurrent cerebrovascular disease following carotid endarterectomy is safe and provides durable freedom from stroke. Most patients are candidates for repeat endarterectomy with patching, but interposition grafting is often required. These results strongly support the continued role of repeat carotid surgery in the treatment of recurrent carotid disease.
authors.affiliation: Department of Surgery, Division of Vascular Surgery, Oregon Health Sciences University, Portland Veterans Affairs Medical Center, USA.
authors.forename: Ahmed M
authors.initials: AM
authors.lastname: Abou-Zamzam
authors.forename: Gregory L
authors.initials: GL
authors.lastname: Moneta
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Landry
authors.forename: Richard A
authors.initials: RA
authors.lastname: Yeager
authors.forename: James M
authors.initials: JM
authors.lastname: Edwards
authors.forename: Donald B
authors.initials: DB
authors.lastname: McConnell
authors.forename: Lloyd M
authors.initials: LM
authors.lastname: Taylor
authors.forename: John M
authors.initials: JM
authors.lastname: Porter
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017130:Angioplasty; D019917:Blood Vessel Prosthesis Implantation; D016893:Carotid Stenosis / Q000453:epidemiology / Q000601:surgery*; D015897:Comorbidity; D016894:Endarterectomy, Carotid; D005260:Female; D006801:Humans; D015993:Life Tables; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012086:Reoperation