The molecular reaction vessels for a transesterification process created by molecular imprinting technique.
A polymeric catalyst was synthesized by co-polymerizing 4(5)-vinylimidazole and itaconic acid with trimethylpropanol trimethacrylate micro spheres. The catalyst obtained catalysed the transesterification process between p-nitrophenyl acetate and hexanol with maximal initial velocity(nu(max)) of 4.73 +/- 0.47 microM min(-1) mg(-1), and turnover rate (k(cat)) of 8.67 min(-1). Using p-nitrophenyl acetate as template, molecular imprinting process enhanced the nu(max) of the polymeric catalyst 3-fold. Each imprinted site can be considered as a single molecular reaction vessel, and achieved a k(cat) of 169 min(-1) towards the conversion of p-nitrophenyl acetate in hexanol.
Meng
Zihui
Z
Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Naka-cho Koganei, Japan. zmeng@engr.ucr.edu
Sode
Koji
K
D002384:Catalysis; D004951:Esterification; D000441:Hexanols / Q000737:chemistry*; D007093:Imidazoles; D008689:Methacrylates / Q000737:chemistry*; D008863:Microspheres; D009596:Nitrophenols / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D013386:Succinates / Q000737:chemistry*
D000441:Hexanols; D007093:Imidazoles; D008689:Methacrylates; D009596:Nitrophenols; D011108:Polymers; D013386:Succinates; C008642:4-nitrophenyl acetate; C005229:itaconic acid