Effect on pKa of metal-bound water molecules in lanthanide ion-induced cyclen "cavities".
[reaction: see text] The macrocyclic cyclen conjugates 1-4 were synthesized with the aim of forming lanthanide ion-based macrocyclic conjugates possessing deep cavities, formed upon complexation to various lanthanide ions. These complexes all possess metal-bound water molecules, where the pKa of the water molecules depends on the nature of the cavity.
Gunnlaugsson
Thorfinnur
T
Department of Chemistry, Trinity College Dublin, Dublin 2, Ireland. gunnlaut@tcd.ie
Brougham
Dermot F
DF
Fanning
Ann-Marie
AM
Nieuwenhuyzen
Mark
M
O'Brien
John E
JE
Viguier
Romain
R