title: [Preliminary study on correlation between double-contrast and serum 5'-nucleotidase of gastric carcinoma].
abstract: OBJECTIVE
  To determine the relationship between double-contrast manifestation and 5'-nucleotidase (5'-NT) of gastric carcinoma.
  
  
  METHODS
  Serum specimens were taken from 41 cases with gastric carcinoma documented by double-contrast visualization and pathology. 5'-NT activity was determined by spectrophotometry. 40 healthy subjects were recruited and studied as normal controls.
  
  
  RESULTS
  The serum level of 5'-NT(1.14 u/ml) in gastric carcinoma group was lower than that of control group (2.60 u/ml) (P < 0.05). Anatomically, it was found that the 5'-NT level of gastric carcinoma gradually increased as the sites of the tumor lined up from the orifice (0.98 u/ml) to the antrum (1.28 u/ml) via the body (1.20 u/ml). 5'-NT of the ulcerative type (0.96 u/ml) was lower than that of the fungating type (1.12 u/ml) or the infiltrating type (1.40 u/ml). 5'-NT(1.53 u/ml) of stage IV gastric carcinoma was higher than that of stage 1 (0.83 u/ml), stage I (0.98 u/ml) and stage III (1.03 u/ml) (P < 0.05).
  
  
  CONCLUSIONS
  The change of 5'-NT from gastric carcinoma was correlated with the site, type or stage shown on the double-contrast images of the tumor.
authors.affiliation: Department of Radiology, West China Hospital, Sichuan China University, Chengdu 610041, China.
authors.forename: Jianqun
authors.initials: J
authors.lastname: Yu
authors.forename: Fangyi
authors.initials: F
authors.lastname: Liao
authors.forename: Manling
authors.initials: M
authors.lastname: Chen
authors.forename: Kaiyu
authors.initials: K
authors.lastname: Yang
mesh_terms: D015720:5'-Nucleotidase / Q000097:blood*; D000230:Adenocarcinoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000201:enzymology; D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D003287:Contrast Media; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000201:enzymology*
chemical_list: D014408:Biomarkers, Tumor; D003287:Contrast Media; D015720:5'-Nucleotidase