[Safety assessment of GM yeast feed additive with cecropin CAD gene].
OBJECTIVE
To evaluate the safety of GM yeast feed additive with cecropin CAD and to study and set up a model of Safety assessment for GM feed and detecting method.


METHODS
To ensure the safety of the GM products, it has been done that to detect and value the safety of receptor organisms and expression products of extrinsic gene, the genetic stability of biologic properties of genomic modified yeast feed and condition of transfer and cumulation of anti-bacterial peptide and its products in circumstance and the feeded animals.


CONCLUSIONS
The receptor animals and expression products of extrinic gene are safe, and the genomic modified products have steady genetic characters. The cectopin CAD neither cumulates in feeded animal nor releases into environment. The genomic modified feed additive is safe.
Deng
Pingjian
P
Shenzhen Center for Disease Control and Prevention, Shenzhen 518020, China.
Fang
Shisong
S
Yang
Dongyan
D
Jiang
Lihua
L
Yu
Xiangqiang
X
Huang
Yongbin
Y
Huang
Ziran
Z
D000821:Animal Feed / Q000633:toxicity*; D000818:Animals; D023181:Antimicrobial Cationic Peptides / Q000235:genetics / Q000378:metabolism*; D002645:Chickens; D033364:Decapoda; D005503:Food Additives / Q000633:toxicity*; D030841:Food, Genetically Modified / Q000633:toxicity*; D051379:Mice; D030781:Organisms, Genetically Modified; D018570:Risk Assessment; D012449:Safety; D013552:Swine; D018675:Toxicity Tests; D015003:Yeasts / Q000235:genetics* / Q000378:metabolism
D023181:Antimicrobial Cationic Peptides; D005503:Food Additives