High precision EPR dosimetry as a reference tool for validation of other techniques.
We present here a particular application area for EPR dosimetry with teeth--use as a source of reference dose values for validation/verification of other retrospective dosimetry techniques and existing dose records. The conditions of application of EPR dosimetry in this role as well as practical design of such studies are shown. Particular attention is given to the requirements to the techniques in terms of precision and throughput, as well as to the issue of availability of samples for analysis and practical solution of this problem. Practical application of this approach is illustrated by several examples of completed validation sub-studies, which were performed in the framework of large-scale post-Chernobyl epidemiological studies.
Chumak
V V
VV
Scientific Center of Radiation Medicine, Melnikova Str., 53, 04050 Kiev, Ukraine. chumak@leed1.kiev.ua
Sholom
S V
SV
Bakhanova
E V
EV
Pasalskaya
L F
LF
Musijachenko
A V
AV
D019985:Benchmarking / Q000379:methods; D001822:Body Burden; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods* / Q000592:standards*; D006801:Humans; D066298:In Vitro Techniques; D038622:Internationality; D011829:Radiation Dosage; D011874:Radiometry / Q000379:methods* / Q000592:standards*; D012015:Reference Standards; D012062:Relative Biological Effectiveness; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014070:Tooth / Q000737:chemistry* / Q000528:radiation effects*