title: Antitermitic and antifungal activities of essential oil of Calocedrus formosana leaf and its composition.
abstract: Calocedrus formosana Florin (Cupressaceae) is an endemic tree species in Taiwan; its timber is recognized for natural decay resistance. To examine the antitermitic and antifungal activities of leaf essential oil and its main constituents, C. formosana leaves were extracted and the essential oils analyzed by GC-MS. Bioactivity tests against the termite Coptotermes formosanus demonstrate that the LC50 value of leaf essential oil is 27.6 mg/g. Furthermore, exposure to T-muurolol caused 100% mortality at a dosage of 5 mg/g after 14 d. Leaf oil constituents displayed activity against four fungi, Lenzites betulina, Pycnoporus coccineus, Trametes versicolor, and Laetiporus sulphureus. Two compounds, alpha-cadinol and T-muurolol, exhibited the strongest antifungal activity. The LC50 values of alpha-cadinol against L. sulphureus, L. betulina, and T. versicolor are 9.9, 28.6, and 30.4 microg/ml, respectively.
authors.affiliation: School of Forestry and Resource Conservation, National Taiwan University, No. 1, Section 4, Roosevelt Road, Taipei 106, Taiwan.
authors.forename: Sen-Sung
authors.initials: SS
authors.lastname: Cheng
authors.forename: Chi-Lin
authors.initials: CL
authors.lastname: Wu
authors.forename: Hui-Ting
authors.initials: HT
authors.lastname: Chang
authors.forename: Yu-Ting
authors.initials: YT
authors.lastname: Kao
authors.forename: Shang-Tzen
authors.initials: ST
authors.lastname: Chang
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000737:chemistry* / Q000494:pharmacology; D029779:Cupressaceae / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D007306:Insecticides / Q000737:chemistry / Q000494:pharmacology; D020049:Isoptera / Q000187:drug effects* / Q000502:physiology; D007928:Lethal Dose 50; D009026:Mortality; D018515:Plant Leaves / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry*; D013729:Terpenes / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D007306:Insecticides; D010938:Plant Oils; C499351:T-muurolol; D013729:Terpenes; C445364:cadinol