title: Emergence of CTX-M-15-producing enterobacteria in Cameroon and characterization of a blaCTX-M-15-carrying element.
abstract: CTX-M-15-producing Klebsiella pneumoniae and Escherichia coli emerged recently in Cameroon. CTX-M-15 was encoded by two different multiresistance plasmids, of which one carried an ISEcp1-bla(CTX-M-15) element flanked by a 5-bp target site duplication and inserted within a Tn2-derived sequence. A truncated form of this element in the second plasmid was identified.
authors.affiliation: Laboratory of Bacteriology, Hellenic Pasteur Institute, Vas. Sofias 127, Athens 11521, Greece.
authors.forename: J
authors.initials: J
authors.lastname: Gangoue-Pieboji
authors.forename: V
authors.initials: V
authors.lastname: Miriagou
authors.forename: S
authors.initials: S
authors.lastname: Vourli
authors.forename: E
authors.initials: E
authors.lastname: Tzelepi
authors.forename: P
authors.initials: P
authors.lastname: Ngassam
authors.forename: L S
authors.initials: LS
authors.lastname: Tzouvelekis
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002163:Cameroon; D004251:DNA Transposable Elements; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D006801:Humans; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D010957:Plasmids; D017422:Sequence Analysis, DNA; D001618:beta-Lactamases / Q000096:biosynthesis* / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D004251:DNA Transposable Elements; C473109:beta-lactamase CTX-M-15; D001618:beta-Lactamases