[Early functional hemispherectomy in hemimegalencephaly associated to refractory epilepsy].
Hemimegalencephaly (HME) is a rare congenital brain malformation of unknown etiology. Patients with HME can present with an early onset epileptic syndrome which is often refractory to medical treatment and associated to impaired neurological development. Functional hemispherectomy (FH) has proven to be a valuable treatment alternative in patients with refractory epilepsy in this setting. Very few children operated under the age of 6 months and bearing HME and catastrophic epilepsy (CE) have been described in the literature. This study reports on 2 kids younger than 6 months with HME and CE submitted to FH with good clinical outcome.
Fonseca
Luiz Fernando
LF
Hospital Centro Geral de Pediatria, Belo Horizonte MG, Brazil.
Melo
Renato Pacheco de
RP
Cukiert
Arthur
A
Burattini
Jose Augusto
JA
Mariani
Pedro Paulo
PP
Brandão
Ródio
R
Ceda
Lauro
L
Baldauf
Cristine Mella
CM
Argentoni
Meire
M
Forster
Cássio
C
Baise
Carla
C
D001921:Brain / Q000002:abnormalities* / Q000601:surgery; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D038421:Hemispherectomy; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed