Self-assembly of chiral DNA nanotubes.
A system of DNA "tiles" that is designed to assemble to form two-dimensional arrays is observed to form narrow ribbons several micrometers in length. The uniform width of the ribbons and lack of frayed edges lead us to propose that they are arrays that have curled and closed on themselves to form tubes. This proposal is confirmed by the observation of tubes with helical order.
Mitchell
James C
JC
Clarendon Laboratory, Department of Physics, University of Oxford, Parks Road, Oxford OX1 3PU, UK.
Harris
J Robin
JR
Malo
Jonathan
J
Bath
Jonathan
J
Turberfield
Andrew J
AJ
D001710:Biotin / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D004277:DNA, Single-Stranded / Q000737:chemistry; D006735:Horseradish Peroxidase / Q000737:chemistry; D046529:Microscopy, Electron, Transmission; D008958:Models, Molecular; D036103:Nanotechnology / Q000379:methods; D043942:Nanotubes / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D013237:Stereoisomerism; D019809:Streptavidin / Q000737:chemistry
D004277:DNA, Single-Stranded; D001710:Biotin; D004247:DNA; D019809:Streptavidin; D006735:Horseradish Peroxidase