[Effect of ginsenoside Rg2 on chemical myocardial ischemia in rats].
OBJECTIVE
To investigate the protective effect of Ginsenoside Rg2 on Chemical myocardial ischemia.


METHODS
The models of myocardial ischemia were built in rats with isoproterenol, sodium nitrite,pituitrin. Ginsenoside Rg2 (iv 2.5, 5.0, 10.0 mg x kg(-1)) were intravenously administered.


RESULTS
Ginsenoside Rg2 could improve the abnormal electrocardiogram (ECG), reduce the arca of myocardial ischemia and improve the abnormal zymologic value of myocardial.


CONCLUSIONS
Ginsenoside Rg2 has inhibitory function on myocardialischemia.
Tian
Jian-ming
JM
Academy of Traditional Chinese Medicine and Materia Medica of Jilin Province, Changchun 130021, Jilin, China.
Li
Hao
H
Ye
Jin-mei
JM
Guo
Wei-fang
WF
Li
Lon-yun
LY
Wang
Li-ping
LP
D000818:Animals; D003402:Creatine Kinase / Q000378:metabolism; D004562:Electrocardiography / Q000187:drug effects; D005260:Female; D036145:Ginsenosides / Q000302:isolation & purification / Q000494:pharmacology*; D007545:Isoproterenol; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D017202:Myocardial Ischemia / Q000139:chemically induced / Q000473:pathology / Q000503:physiopathology; D009206:Myocardium / Q000473:pathology*; D005894:Panax / Q000737:chemistry; D010909:Pituitary Hormones, Posterior; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D012977:Sodium Nitrite; D013482:Superoxide Dismutase / Q000378:metabolism*
D036145:Ginsenosides; D010909:Pituitary Hormones, Posterior; D008315:Malondialdehyde; C026474:ginsenoside Rg2; D013482:Superoxide Dismutase; D003402:Creatine Kinase; D007545:Isoproterenol; D012977:Sodium Nitrite