title: A third case of cardiac neoplasm in a fetus with Beckwith-Wiedemann syndrome: epicardial angiofibroma.
abstract: OBJECTIVE
  A personal observation of a 20-week-old fetus with Beckwith-Wiedemann syndrome (BWS) presenting epicardial angiofibroma prompted us to evaluate cardiac neoplasms in this genetic condition.
  
  
  METHODS
  We performed an autopsy and a histological evaluation of the fetus, and searched the literature for cardiac anomalies in BWS.
  
  
  RESULTS
  Although cardiac tumors are exceptional and although BWS is rare, we found two other cardiac neoplasms in infants with BWS, whereas no more than one was expected.
  
  
  CONCLUSIONS
  Besides an excess of cardiac malformation, BWS seems to favor an excess of cardiac tumors, which may occur very early.
authors.affiliation: Laboratoire d'Anatomie Pathologique Centre Hospitalier, Tulle, France. daniel.satge@ch-tulle.fr
authors.forename: Daniel
authors.initials: D
authors.lastname: Satgé
authors.forename: Evelyne
authors.initials: E
authors.lastname: Vidalo
authors.forename: François
authors.initials: F
authors.lastname: Desfarges
authors.forename: Bernard
authors.initials: B
authors.lastname: de Geeter
mesh_terms: D000328:Adult; D018322:Angiofibroma / Q000209:etiology* / Q000473:pathology; D001506:Beckwith-Wiedemann Syndrome / Q000150:complications*; D005260:Female; D005315:Fetal Diseases; D006222:Hamartoma / Q000209:etiology / Q000473:pathology; D006331:Heart Diseases / Q000209:etiology / Q000473:pathology; D006338:Heart Neoplasms / Q000209:etiology* / Q000473:pathology; D006801:Humans; D010496:Pericardium; D011247:Pregnancy; D011261:Pregnancy Trimester, First