title: Use of fibrin sealant in laparoscopic gastric bypass for the morbidly obese.
abstract: Roux-en-Y gastric bypass is the most commonly performed bariatric operation in the USA. Anastomotic leak is one of the devastating complications in this operation. By using fibrin sealant around the anastomosis, surgeons can achieve better hemostasis around the suture-line and prevent or decrease the incidence of anastomotic leaks. This paper discusses the biological and clinical evidence for use of fibrin sealant in laparoscopic gastric bypass.
authors.affiliation: Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
authors.forename: Meng-G Martin
authors.initials: MG
authors.lastname: Lee
authors.forename: David A
authors.initials: DA
authors.lastname: Provost
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Jones
mesh_terms: D000713:Anastomosis, Roux-en-Y / Q000009:adverse effects / Q000379:methods; D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D005500:Follow-Up Studies; D015390:Gastric Bypass / Q000009:adverse effects / Q000379:methods*; D006471:Gastrointestinal Hemorrhage / Q000517:prevention & control; D005773:Gastroscopy / Q000379:methods; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods*; D008297:Male; D009767:Obesity, Morbid / Q000175:diagnosis / Q000601:surgery*; D011446:Prospective Studies; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D034421:Sus scrofa; D013718:Tensile Strength; D016896:Treatment Outcome
chemical_list: D015718:Fibrin Tissue Adhesive