title: EchoBASE: an integrated post-genomic database for Escherichia coli.
abstract: EchoBASE (http://www.ecoli-york.org) is a relational database designed to contain and manipulate information from post-genomic experiments using the model bacterium Escherichia coli K-12. Its aim is to collate information from a wide range of sources to provide clues to the functions of the approximately 1500 gene products that have no confirmed cellular function. The database is built on an enhanced annotation of the updated genome sequence of strain MG1655 and the association of experimental data with the E.coli genes and their products. Experiments that can be held within EchoBASE include proteomics studies, microarray data, protein-protein interaction data, structural data and bioinformatics studies. EchoBASE also contains annotated information on 'orphan' enzyme activities from this microbe to aid characterization of the proteins that catalyse these elusive biochemical reactions.
authors.affiliation: Department of Biology (Area 10), University of York, PO Box 373,York, YO10 5YW, UK.
authors.forename: Raju V
authors.initials: RV
authors.lastname: Misra
authors.forename: Richard S P
authors.initials: RS
authors.lastname: Horler
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Reindl
authors.forename: Igor I
authors.initials: II
authors.lastname: Goryanin
authors.forename: Gavin H
authors.initials: GH
authors.lastname: Thomas
mesh_terms: D030541:Databases, Genetic; D048168:Escherichia coli K12 / Q000201:enzymology / Q000235:genetics* / Q000378:metabolism; D029968:Escherichia coli Proteins / Q000737:chemistry / Q000235:genetics* / Q000502:physiology; D016680:Genome, Bacterial; D023281:Genomics; D018511:Systems Integration; D014584:User-Computer Interface
chemical_list: D029968:Escherichia coli Proteins