title: Optimisation of strain rate imaging for application to stress echocardiography.
abstract: We sought to improve the feasibility of strain rate imaging (SRI) during dobutamine stress echocardiography (DSE) in 56 subjects at low risk of coronary disease. The impact of several SRI changes during acquisition were studied, including: (1) changing from fundamental to harmonic imaging; (2) parallel beamforming; (3) alteration of spatial resolution and (4) narrow sector acquisition. We assessed SR signal quality, a quantitative measure of signal noise and measurements of SRI. Of 1462 segments evaluated, 6% were uninterpretable at rest and 8% at peak stress. Signal quality was optimised by increasing temporal (p = 0.01) and spatial resolution (p < 0.0001 vs. baseline imaging) at rest and peak. Increasing spatial resolution also minimised signal noise (p < 0.0001). Inter-observer variability of time to peak SR and peak SR were less with high temporal and spatial resolution. SRI quality can be improved with harmonic imaging and higher temporal resolution but optimisation of spatial resolution is critical.
authors.affiliation: University of Queensland, Brisbane, Australia.
authors.forename: Lizelle
authors.initials: L
authors.lastname: Hanekom
authors.forename: Vidar
authors.initials: V
authors.lastname: Lundberg
authors.forename: Rodel
authors.initials: R
authors.lastname: Leano
authors.forename: Thomas H
authors.initials: TH
authors.lastname: Marwick
mesh_terms: D002316:Cardiotonic Agents; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D004280:Dobutamine; D025401:Echocardiography, Stress / Q000379:methods*; D005260:Female; D006321:Heart / Q000187:drug effects; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012307:Risk Factors; D012815:Signal Processing, Computer-Assisted; D013599:Systole / Q000502:physiology
chemical_list: D002316:Cardiotonic Agents; D004280:Dobutamine