title: Cerebellar lesions in the PICA but not SCA territory impair cognition.
abstract: The authors sought to clarify whether lesions in different parts of the cerebellum result in differential cognitive and affective impairment. Six subjects with cerebellar lesions due to posterior inferior cerebellar artery (PICA) infarction, five subjects with lesions in the SCA vascular territory, and 11 matched controls were administered a battery of standard neuropsychological tests. PICA lesions but not SCA lesions resulted in cognitive and affective deficits pointing to a dominant role of posterior cerebellar regions in cognitive and affective processing.
authors.affiliation: Department of Clinical Psychology and Psychotherapy, University of Marburg, Gutenbergstr. 18, D-35032 Marburg, Germany, FRG. exnerc@staff.uni-marburg.de
authors.forename: Cornelia
authors.initials: C
authors.lastname: Exner
authors.forename: Godehard
authors.initials: G
authors.lastname: Weniger
authors.forename: Eva
authors.initials: E
authors.lastname: Irle
mesh_terms: D001288:Attention / Q000502:physiology; D002531:Cerebellum / Q000098:blood supply / Q000503:physiopathology*; D002544:Cerebral Infarction / Q000523:psychology; D003072:Cognition Disorders / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D014854:Lateral Medullary Syndrome / Q000523:psychology*; D008128:Logic; D008279:Magnetic Resonance Imaging; D008297:Male; D008569:Memory Disorders / Q000209:etiology* / Q000503:physiopathology; D011939:Mental Recall; D008875:Middle Aged; D009483:Neuropsychological Tests; D014706:Verbal Learning