The thioredoxin h system: potential applications.
The thioredoxin h system has the specific capability to reduce intramolecular disulfide bonds of proteins, thereby modifying their tertiary structure. It is involved in many processes: in the activation or deactivation of enzymes and enzyme inhibitors and in the germination process. This system can be used to improve the breadmaking quality of wheat by strengthening the dough. It can also decrease the epitope accessibility, then modifying the response of the IgE immune system. Transgenic barley and wheat have been created to confirm the functionality of the NADP-dependent thioredoxin h system.
Joudrier
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UMR PIA (CIRAD-INRA-ENSA), 2, Place Viala, 34060 Montpellier cedex, France. joudrier@ensam.inra.fr
Gautier
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de Lamotte
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Kobrehel
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D000485:Allergens / Q000737:chemistry / Q000276:immunology; D001939:Bread; D002523:Edible Grain / Q000235:genetics* / Q000378:metabolism; D019649:Food Industry / Q000639:trends*; D018525:Germination / Q000502:physiology*; D001467:Hordeum / Q000235:genetics; D009249:NADP / Q000378:metabolism; D010940:Plant Proteins / Q000737:chemistry / Q000276:immunology; D030821:Plants, Genetically Modified; D054480:Thioredoxin h; D013879:Thioredoxins / Q000235:genetics / Q000378:metabolism*; D014908:Triticum / Q000235:genetics
D000485:Allergens; D010940:Plant Proteins; D054480:Thioredoxin h; D013879:Thioredoxins; D009249:NADP