title: Evidence-based practice for the use of N-acetylcysteine.
abstract: The use of N-acetylcysteine has increased in the prevention of radiographic contrast induced nephrotoxicity. Many nurses need to be aware of the proper administration and action of this prophylactic agent. This article discusses the research behind the use of N-acetylcysteine and the protocol for administration to prevent radiographic contrast-induced nephrotoxicity.
authors.affiliation: Purdue University Calumet, Hammond, IN 46323, USA.
authors.forename: Maureen T
authors.initials: MT
authors.lastname: Marthaler
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Keresztes
mesh_terms: D000111:Acetylcysteine / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D058186:Acute Kidney Injury / Q000139:chemically induced / Q000517:prevention & control; D003287:Contrast Media / Q000009:adverse effects*; D016903:Drug Monitoring / Q000451:nursing; D019317:Evidence-Based Medicine; D005440:Fluid Therapy; D016166:Free Radical Scavengers; D006801:Humans; D024802:Nurse's Role; D018579:Patient Selection; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D003287:Contrast Media; D016166:Free Radical Scavengers; D000111:Acetylcysteine