title: Role of clinical, patient-reported outcome and medico-economic studies in the public hospital drug formulary decision-making process: results of a European survey.
abstract: BACKGROUND
  Over the past 20 years, drug information has grown rapidly, but little is known of its actual use in hospital decision-making.
  
  
  OBJECTIVE
  To describe the role of clinical studies (CS), patient-reported outcome studies (PROS) and medico-economic studies (MES) in public hospital drug formulary decision-making.
  
  
  METHODS
  A postal survey was conducted in 400 randomly selected public hospitals stratified by country (France, Germany, The Netherlands and the United Kingdom) and profession (doctor or pharmacist).
  
  
  RESULTS
  The participation rate was 78% (143 doctors and 169 pharmacists), and the response rate 44%. Responders were generally interested in CS (86%), PROS (71%) and MES (71%). They reported high but unmet expectations concerning information available on PROS and MES, the methodology of these studies and interpretation of the results.
  
  
  CONCLUSIONS
  To increase the impact of PROS and MES, we suggest training decision-makers in the study methodology and provide them with support of health and economic experts.
authors.affiliation: MAPI Values, Le d'Aubigny, 27, rue de la Villette, 69003 Lyon, France.
authors.forename: Elodie
authors.initials: E
authors.lastname: Haslé-Pham
authors.forename: Benoit
authors.initials: B
authors.lastname: Arnould
authors.forename: Hans-Martin
authors.initials: HM
authors.lastname: Späth
authors.forename: Alain
authors.initials: A
authors.lastname: Follet
authors.forename: Gérard
authors.initials: G
authors.lastname: Duru
authors.forename: Patrick
authors.initials: P
authors.lastname: Marquis
mesh_terms: D002986:Clinical Trials as Topic; D003625:Data Collection; D003659:Decision Making, Organizational; D005060:Europe; D005569:Formularies as Topic; D006779:Hospitals, Public / Q000458:organization & administration*; D010361:Patients; D012650:Self Disclosure; D016896:Treatment Outcome