title: [Early functional hemispherectomy in hemimegalencephaly associated to refractory epilepsy].
abstract: Hemimegalencephaly (HME) is a rare congenital brain malformation of unknown etiology. Patients with HME can present with an early onset epileptic syndrome which is often refractory to medical treatment and associated to impaired neurological development. Functional hemispherectomy (FH) has proven to be a valuable treatment alternative in patients with refractory epilepsy in this setting. Very few children operated under the age of 6 months and bearing HME and catastrophic epilepsy (CE) have been described in the literature. This study reports on 2 kids younger than 6 months with HME and CE submitted to FH with good clinical outcome.
authors.affiliation: Hospital Centro Geral de Pediatria, Belo Horizonte MG, Brazil.
authors.forename: Luiz Fernando
authors.initials: LF
authors.lastname: Fonseca
authors.forename: Renato Pacheco de
authors.initials: RP
authors.lastname: Melo
authors.forename: Arthur
authors.initials: A
authors.lastname: Cukiert
authors.forename: Jose Augusto
authors.initials: JA
authors.lastname: Burattini
authors.forename: Pedro Paulo
authors.initials: PP
authors.lastname: Mariani
authors.forename: Ródio
authors.initials: R
authors.lastname: Brandão
authors.forename: Lauro
authors.initials: L
authors.lastname: Ceda
authors.forename: Cristine Mella
authors.initials: CM
authors.lastname: Baldauf
authors.forename: Meire
authors.initials: M
authors.lastname: Argentoni
authors.forename: Cássio
authors.initials: C
authors.lastname: Forster
authors.forename: Carla
authors.initials: C
authors.lastname: Baise
mesh_terms: D001921:Brain / Q000002:abnormalities* / Q000601:surgery; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D038421:Hemispherectomy; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed