title: TAT conjugated, FITC doped silica nanoparticles for bioimaging applications.
abstract: Water-in-oil (w/o) microemulsion synthesis of 70 nm size monodisperse TAT (a cell penetrating peptide, CPP) conjugated, FITC (fluorescein isothiocyanate) doped silica nanoparticles (TAT-FSNPs) is reported; human lung adenocarcinoma (A549) cells (in vitro) and rat brain tissue (in vivo) were successfully labeled using TAT-FSNPs.
authors.affiliation: Department of Neurological Surgery, University of Florida, PO Box 100265, Gainesville, FL 32610, USA. santra@neurosurgery.ufl.edu
authors.forename: Swadeshmukul
authors.initials: S
authors.lastname: Santra
authors.forename: Heesun
authors.initials: H
authors.lastname: Yang
authors.forename: Debamitra
authors.initials: D
authors.lastname: Dutta
authors.forename: Jessie T
authors.initials: JT
authors.lastname: Stanley
authors.forename: Paul H
authors.initials: PH
authors.lastname: Holloway
authors.forename: Weihong
authors.initials: W
authors.lastname: Tan
authors.forename: Brij M
authors.initials: BM
authors.lastname: Moudgil
authors.forename: Robert A
authors.initials: RA
authors.lastname: Mericle
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism; D045744:Cell Line, Tumor; D004655:Emulsions / Q000737:chemistry; D016650:Fluorescein-5-isothiocyanate / Q000032:analysis* / Q000737:chemistry*; D015696:Gene Products, tat / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D046529:Microscopy, Electron, Transmission; D008856:Microscopy, Fluorescence; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D051381:Rats; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D004655:Emulsions; D015696:Gene Products, tat; D012822:Silicon Dioxide; D016650:Fluorescein-5-isothiocyanate