Some endotoxin-induced clinical and biochemical changes in plasma of camels (Camelus dromedarius).
Intravenous administration of endotoxin, prepared from E. coli serotype O55:B5, at a dose of 0.1 microg/kg body weight to calves and adult camels induced fever and increased haematocrit, triiodothyronine and cortisol values. The endotoxin-treated animals showed significantly decreased (p < 0.05) total protein, urea, glucose and creatinine. A significant increase was seen in the activity of aspartate aminotransaminase and creatine kinase. These results demonstrate high sensitivity of camels to endotoxin.
Al-Dughaym
A M
AM
Department of Microbiology and Parasitology, College of Veterinary Medicine and Animal Resources, King Faisal University, PO Box 1757, Al-Ahsa 31982, Saudi Arabia. amd1995@hotmail.com
D000818:Animals; D001774:Blood Chemical Analysis / Q000662:veterinary; D001786:Blood Glucose / Q000032:analysis; D001798:Blood Proteins / Q000032:analysis; D002162:Camelus / Q000097:blood*; D003404:Creatinine / Q000097:blood; D004731:Endotoxins / Q000008:administration & dosage*; D004798:Enzymes / Q000097:blood / Q000378:metabolism; D005260:Female; D005334:Fever / Q000097:blood / Q000139:chemically induced / Q000662:veterinary; D006400:Hematocrit / Q000662:veterinary; D006403:Hematologic Tests / Q000662:veterinary; D006854:Hydrocortisone / Q000097:blood; D007275:Injections, Intravenous / Q000662:veterinary; D008297:Male; D011897:Random Allocation; D014284:Triiodothyronine / Q000097:blood
D001786:Blood Glucose; D001798:Blood Proteins; D004731:Endotoxins; D004798:Enzymes; D014284:Triiodothyronine; C044101:endotoxin, Escherichia coli; D003404:Creatinine; D006854:Hydrocortisone