Piperidone derivative from Dalbergia sympathetica.
An alcoholic extract of Dalbergia sympathetica, on column chromatography, yielded a compound which analyzed for C(6)H(11)NO(3) (M(+) 145). The IR spectrum of the compound showed the presence of carbonyl and hydroxyl groups. PMR, (13)C and DEPT NMR spectral studies of the compound showed the presence of one N-methyl, two methine and two methylene groups. A quaternary carbon signal at delta 172.88 ppm was assigned to C-2 carbonyl of the compound. From all the above observations and also from the HMQC 2D NMR spectrum, the compound was identified as 3, 6-dihydroxy-N-methyl-2-piperidone. This is the first report of the natural occurrence of this compound from plant sources.
Nagarajan
N Shanmugam
NS
Department of Chemistry, Gandhigram Rural Institute, Deemed University, Gandhigram-624 302, Tamil Nadu, India.
Rao
R Priya
RP
Manoj
C Narayanan
CN
Sethuraman
M Gopalakrishnan
MG
D002247:Carbon Isotopes; D035782:Dalbergia / Q000737:chemistry*; D007194:India; D009682:Magnetic Resonance Spectroscopy / Q000379:methods* / Q000592:standards*; D010881:Piperidones / Q000032:analysis / Q000737:chemistry* / Q000302:isolation & purification / Q000592:standards*; D011522:Protons; D012016:Reference Values
D002247:Carbon Isotopes; D010881:Piperidones; D011522:Protons