title: PDB_TM: selection and membrane localization of transmembrane proteins in the protein data bank.
abstract: PDB_TM is a database for transmembrane proteins with known structures. It aims to collect all transmembrane proteins that are deposited in the protein structure database (PDB) and to determine their membrane-spanning regions. These assignments are based on the TMDET algorithm, which uses only structural information to locate the most likely position of the lipid bilayer and to distinguish between transmembrane and globular proteins. This algorithm was applied to all PDB entries and the results were collected in the PDB_TM database. By using TMDET algorithm, the PDB_TM database can be automatically updated every week, keeping it synchronized with the latest PDB updates. The PDB_TM database is available at http://www.enzim.hu/PDB_TM.
authors.affiliation: Institute of Enzymology, BRC, Hungarian Academy of Sciences, H-1518 Budapest, P.O. Box 7, Hungary.
authors.forename: Gábor E
authors.initials: GE
authors.lastname: Tusnády
authors.forename: Zsuzsanna
authors.initials: Z
authors.lastname: Dosztányi
authors.forename: István
authors.initials: I
authors.lastname: Simon
mesh_terms: D000465:Algorithms; D003196:Computer Graphics; D030562:Databases, Protein; D020407:Internet; D008051:Lipid Bilayers / Q000737:chemistry; D008565:Membrane Proteins / Q000032:analysis* / Q000737:chemistry*; D014584:User-Computer Interface
chemical_list: D008051:Lipid Bilayers; D008565:Membrane Proteins