[Dynamic changes of serum antibody titer and liver ultrastructural pathology in acute sporadic hepatitis E virus infected patients].
7 acute hepatitis E patients were tested for anti-HEV IgM and IgG antibodies by EIA. It revealed that anti-HEV IgM and IgG antibody titers were the highest at day 10-45 of the illness, and anti-HEV IgM declined gradually and totally lost within 2 months. Anti-HEV IgG had a similar condition to anti-HEV IgM, but at 7th month there still had 3 cases (40%) remained to be antibody positive. One case was examined for ultrastructural pathology. The swelling of liver cells on the fortieth day of illness was still to be found, the vacuolation of cytoplasm and condensation of mitochondria were present in liver cells.
Liao
S
S
Department of Digestion of Affiliated Tian Tan Hospital, Capital University of Medicine, Beijing 100050.
Yang
Z
Z
Jiang
Y
Y
Zhan
M
M
D000208:Acute Disease; D000328:Adult; D000368:Aged; D005260:Female; D006508:Hepatitis Antibodies / Q000097:blood*; D016751:Hepatitis E / Q000276:immunology* / Q000473:pathology* / Q000821:virology; D016752:Hepatitis E virus / Q000276:immunology*; D006801:Humans; D008099:Liver / Q000473:pathology / Q000648:ultrastructure*; D008297:Male; D008875:Middle Aged; D055815:Young Adult
D006508:Hepatitis Antibodies