Safety of stress testing during the evolution of unstable angina pectoris or non-ST-elevation myocardial infarction.
Patients (n = 1,106) were chosen from the conservative arm of the Treat Angina with aggrastat and determine Cost of Therapy with an Invasive or Conservative Strategy-Thrombolysis In Myocardial Infarction (TACTICS-TIMI) 18 trial. Only 1 patient had a myocardial infarction and another died on the day of stress testing (mortality 0.12%). In patients with unstable angina pectoris or non-ST-elevation myocardial infarction treated with aspirin, heparin, and tirofiban, performance of an exercise or a pharmacologic stress test in selected patients within 48 to 72 hours after admission appears to be associated with a low risk of complications.
Karha
Juhana
J
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA. karhaj@ccf.org
Gibson
C Michael
CM
Murphy
Sabina A
SA
Dibattiste
Peter M
PM
Cannon
Christopher P
CP
D000789:Angina, Unstable / Q000175:diagnosis*; D001241:Aspirin / Q000627:therapeutic use; D005080:Exercise Test / Q000009:adverse effects / Q000379:methods; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000188:drug therapy; D012449:Safety; D000077466:Tirofiban; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000627:therapeutic use
D014443:Tyrosine; D006493:Heparin; D000077466:Tirofiban; D001241:Aspirin