title: Creation of a master table for checking indication and contraindication of medicine from a knowledge base linked with a thesaurus.
abstract: To develop a system for checking indication and contraindication of medicines in prescription order entry system, a master table consisting of the disease names corresponding to the medicines adopted in a hospital is needed. The creation of this table requires a considerable manpower. We developed a Web-based system for constructing a medicine/disease thesaurus and a knowledge base. By authority management of users, this system enables many specialists to create the thesaurus collaboratively without confusion. It supports the creation of a knowledge base using concept names by referring to the thesaurus, which is automatically converted to the check master table. When a disease name or medicine name was added to the thesaurus, the check table was automatically updated. We constructed a thesaurus and a knowledge base in the field of circulatory system disease. The knowledge base linked with the thesaurus proved to be efficient for making the check master table for indication/contraindication of medicines.
authors.affiliation: Department of Medical Information Science, Graduate School of Medicine, Osaka University, Suita, Osaka 565-0871, Japan. smji@hp-info.med.osaka-u.ac.jp
authors.forename: Shanmei
authors.initials: S
authors.lastname: Ji
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Matsumura
authors.forename: Shigeki
authors.initials: S
authors.lastname: Kuwata
authors.forename: Hirohiko
authors.initials: H
authors.lastname: Nakano
authors.forename: Yufeng
authors.initials: Y
authors.lastname: Chen
authors.forename: Tadamasa
authors.initials: T
authors.lastname: Teratani
authors.forename: Qiyan
authors.initials: Q
authors.lastname: Zhang
authors.forename: Takahiro
authors.initials: T
authors.lastname: Mineno
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takeda
mesh_terms: D001185:Artificial Intelligence; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000188:drug therapy; D016303:Clinical Pharmacy Information Systems; D000075202:Contraindications; D011307:Drug Prescriptions; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet; D007564:Japan; D008492:Medical Informatics Computing; D008508:Medication Errors / Q000517:prevention & control*; D008510:Medication Systems, Hospital / Q000458:organization & administration*; D012985:Software Design; D018875:Vocabulary, Controlled
chemical_list: D002121:Calcium Channel Blockers