[Parathormone--well known threats and new perspectives].
We present the basic physiologic principles of parathormone activity and the clinical problems most often associated with hyperparathyroidism. From the other side, emphasizing the specificity of pulsating subcutaneous administration of parathormone we revealed the possibility of introduction of this drug as a very effective agent in the treatment of osteoporosis because of its stimulating effect on osteoblasts, increase of bone turnover and reduction of bone fractures.
Nowak
Zbigniew
Z
Wojskowy Instytut Medyczny, Klinika Nefrologii ze Stacja Dializ CSK MON w Warszawie. zbnowak@wp.pl
D016723:Bone Remodeling / Q000187:drug effects*; D004334:Drug Administration Schedule; D006801:Humans; D007279:Injections, Subcutaneous; D010006:Osteoblasts / Q000187:drug effects* / Q000378:metabolism; D010024:Osteoporosis / Q000188:drug therapy* / Q000378:metabolism / Q000517:prevention & control; D010281:Parathyroid Hormone / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use; D016896:Treatment Outcome
D010281:Parathyroid Hormone