Calculation of the peak concentration of 2-chlorobenzamide generated in the hydrolysis of the benzoylphenylurea insecticide 1-(2-chlorobenzoyl)-3-(4-chlorophenyl)urea.
1-(2-chlorobenzoyl)-3-(4-chlorophenyl)urea (CCU), a new analogue of diflubenuron and PH-6038, has been widely used in agriculture and forestry as a molt-inhibiting hormone insecticide which was developed in China. 2-Chlorobenzamide, a main degradation product of CCU in the environment, has been identified as a potential carcinogen, so the content of 2-chlorobenzamide from the breakup of CCU will directly affect the environmental safety of CCU. In this paper we describe a simple, rapid, and convenient prediction model for predicting the level and time of occurrence of the peak concentration of 2-chlorobenzamide in the hydrolysis of CCU verified by experimental data. The time for reaching the peak concentration of 2-chlorobenzamide (tm) at 25 degrees C and pH 6 is 13.5 d, and the maximum concentration of 2-chlorobenzamide (ym) is 3.2% of the initial concentration of CCU according to the results from the prediction model. These results are similar to the real values from the experiments, which are 22 d and 1.6% of the initial concentration of CCU, respectively. The difference between the values of the prediction and experiment is discussed, and it is demonstrated that the predicting model is highly credible.
Lu
Wenying
W
Henan Key Laboratory for Environmental Pollution Control and School of Chemistry and Environmental Sciences, Henan Normal University, Xinxiang 453007, Henan, People's Republic of China.
Zhou
Qingxiang
Q
Liu
Guoguang
G
D001549:Benzamides / Q000032:analysis*; D002273:Carcinogens / Q000032:analysis; D004785:Environmental Pollutants / Q000032:analysis; D006207:Half-Life; D006868:Hydrolysis; D007306:Insecticides / Q000737:chemistry*; D013997:Time Factors; D014508:Urea / Q000031:analogs & derivatives* / Q000737:chemistry*
C495513:1-(2-chlorobenzoyl)-3-(4-chlorophenyl)urea; D001549:Benzamides; D002273:Carcinogens; D004785:Environmental Pollutants; D007306:Insecticides; D014508:Urea; C412475:2-chlorobenzamide