title: MR imaging of apparent small-bowel perfusion for diagnosing mesenteric ischemia: feasibility study.
abstract: The purpose of this study, which was approved by the institutional review board, was to assess the differentiation of individuals with from those without mesenteric ischemia. All subjects provided written informed consent. Six healthy volunteers and six patients with documented chronic mesenteric ischemia underwent magnetic resonance (MR) imaging with and without oral caloric stimulation. After intravenous administration of paramagnetic contrast material, signal intensity values of the small-bowel wall were measured up to 130 seconds after contrast material injection. Volunteers and patients, respectively, had maximum enhancement of the bowel wall between 70 and 85 seconds after contrast material administration that amounted to 269% and 267% without and 425% and 333% with caloric stimulation. MR imaging assessment of small-bowel perfusion is possible and seems feasible for differentiating individuals with from those without mesenteric ischemia.
authors.affiliation: Department of Diagnostic and Interventional Radiology, University Hospital Essen, Hufelandstrasse 55, D-45122 Essen, Germany. thomas.lauenstein@uni-essen.de
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Lauenstein
authors.forename: Waleed
authors.initials: W
authors.lastname: Ajaj
authors.forename: Burcu
authors.initials: B
authors.lastname: Narin
authors.forename: Susanne C
authors.initials: SC
authors.lastname: Göhde
authors.forename: Knut
authors.initials: K
authors.lastname: Kröger
authors.forename: Jörg F
authors.initials: JF
authors.lastname: Debatin
authors.forename: Stefan G
authors.initials: SG
authors.lastname: Rühm
mesh_terms: D000328:Adult; D003287:Contrast Media; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007421:Intestine, Small / Q000033:anatomy & histology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008641:Mesenteric Vascular Occlusion / Q000175:diagnosis*; D009942:Organometallic Compounds
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; C090600:gadobutrol