LiveBench-8: the large-scale, continuous assessment of automated protein structure prediction.
We present the results of the evaluation of the latest LiveBench-8 experiment. These results provide a snapshot view of the state of the art in automated protein structure prediction, just before the 2004 CAFASP-4/CASP-6 experiments begin. The last CAFASP/CASP experiments demonstrated that automated meta-predictors entail a significant advance in the field, already challenging most human expert predictors. LiveBench-8 corroborates the superior performance of meta-predictors, which are able to produce useful predictions for over one-half of the test targets. More importantly, LiveBench-8 identifies a handful of recently developed autonomous (nonmeta) servers that perform at the very top, suggesting that further progress in the individual methods has recently been obtained.
Rychlewski
Leszek
L
BioInfoBank Institute, Limanowskiego 24A/16, 60-744 Poznan, Poland.
Fischer
Daniel
D
D001331:Automation / Q000379:methods; D019295:Computational Biology / Q000379:methods*; D030562:Databases, Protein; D006801:Humans; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D012680:Sensitivity and Specificity; D012984:Software
D011506:Proteins