title: Extremely potent antifeedant neo-clerodane derivatives of scutecyprol A.
abstract: Two known neo-clerodane diterpenoids, scutecyprol A (1) and scutalbin C (2), have been isolated from the acetone extract of the aerial parts of Scutellaria sieberi. The antifeedant activity of scutecyprol A (1), of its 15-oxo derivative (3), and of several halohydrins (4-9), synthesized starting from compounds 1 and 3, against Spodoptera littoralis have been determined and structure-antifeedant relationships are discussed.
authors.affiliation: Dipartimento di Chimica Organica E. Paterno, Università di Palermo, viale delle Scienze, Parco d'Orleans II, 90128 Palermo, Italy.
authors.forename: Sergio
authors.initials: S
authors.lastname: Rosselli
authors.forename: Antonella
authors.initials: A
authors.lastname: Maggio
authors.forename: Franco
authors.initials: F
authors.lastname: Piozzi
authors.forename: Monique S J
authors.initials: MS
authors.lastname: Simmonds
authors.forename: Maurizio
authors.initials: M
authors.lastname: Bruno
mesh_terms: D000818:Animals; D045785:Diterpenes, Clerodane / Q000737:chemistry / Q000302:isolation & purification*; D007306:Insecticides / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification*; D031363:Scutellaria / Q000737:chemistry*; D018411:Spodoptera
chemical_list: D045785:Diterpenes, Clerodane; D007306:Insecticides; C495516:scutalbin C; C495515:scutecyprol A