Antibodies to type III group B streptococcal polysaccharide in breast milk.
We compared concentrations of type III group B streptococcal capsular polysaccharide (CPS)-specific IgG and IgA in archived 2-month-postpartum breast milk from 9 women with > or =1 microg/ml and 9 with < 1 microg/ml type III CPS-specific IgG in serum. Type III CPS-specific antibodies were not detectable consistently but were measurable in breast milk from some women in both groups, indicating their potential for a role in prevention or amelioration of late onset group B streptococcal disease.
Edwards
Morven S
MS
Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. morvene@bcm.tmc.edu
Munoz
Flor M
FM
Baker
Carol J
CJ
D000328:Adult; D000907:Antibodies, Bacterial / Q000276:immunology*; D001942:Breast Feeding; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology; D007074:Immunoglobulin G / Q000276:immunology; D008895:Milk, Human / Q000276:immunology*; D009504:Neutrophils / Q000276:immunology; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D012189:Retrospective Studies; D013292:Streptococcus agalactiae / Q000276:immunology
D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D011135:Polysaccharides, Bacterial; C032263:streptococcal polysaccharide type III group B