title: Disseminated tuberculosis complicating anti-TNF-alpha treatment.
abstract: An unusually large number of cases of tuberculosis, often of miliary or disseminated form, have been reported in patients receiving infliximab therapy for rheumatoid arthritis or Crohn's disease. We describe a patient with rheumatoid arthritis who was treated with infliximab and became systemically ill with Mycobacterium tuberculosis-disseminated infection. Patients who are candidates for treatment with tumour necrosis factor-alfa inhibitors should be evaluated for the presence of latent or active
authors.affiliation: Department of Respiratory Medicine, University of Athens Medical School, Sotiria Hospital, Athens, Greece.
authors.forename: K
authors.initials: K
authors.lastname: Dimakou
authors.forename: D
authors.initials: D
authors.lastname: Papaioannides
authors.forename: P
authors.initials: P
authors.lastname: Latsi
authors.forename: S
authors.initials: S
authors.lastname: Katsimboula
authors.forename: P
authors.initials: P
authors.lastname: Korantzopoulos
authors.forename: D
authors.initials: D
authors.lastname: Orphanidou
mesh_terms: D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D000075202:Contraindications; D005260:Female; D006801:Humans; D000069285:Infliximab; D008875:Middle Aged; D009894:Opportunistic Infections / Q000150:complications* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014391:Tuberculosis, Miliary / Q000150:complications* / Q000000981:diagnostic imaging; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000000981:diagnostic imaging; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents; D014409:Tumor Necrosis Factor-alpha; D000069285:Infliximab