Antifungal properties of pristimerin and celastrol isolated from Celastrus hypoleucus.
Pristimerin and celastrol isolated from the roots of Celastrus hypoleucus (Oliv) Warb f argutior Loes exhibited inhibitory effects against diverse phytopathogenic fungi. Pristimerin and celastrol were found to inhibit the mycelial growth of Rhizoctonia solani Kuhn and Glomerella cingulata (Stonem) Spauld & Schrenk in vitro by 83.6 and 62.6%, respectively, at 10 microg ml(-1). Pristimerin showed good preventive effect (96.7% at 100 microg ml(-1)) and curative effect (66.5% at 100 microg ml(-1)) against wheat powdery mildew in vivo. For celastrol, the preventive and curative effects against wheat powdery mildew were 80.5 and 45.4%, respectively, at 100 microg ml(-1).
Luo
Du-Qiang
DQ
Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China.
Wang
Hong
H
Tian
Xuan
X
Shao
Hong-Jun
HJ
Liu
Ji-Kai
JK
D031247:Celastrus / Q000737:chemistry*; D005659:Fungicides, Industrial / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D015394:Molecular Structure; D053978:Pentacyclic Triterpenes; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
D005659:Fungicides, Industrial; D053978:Pentacyclic Triterpenes; D014315:Triterpenes; C050414:celastrol