Molecular detection of Treponema denticola and Porphyromonas gingivalis in carotid and aortic atheromatous plaques by FISH: report of two cases.
Treponema denticola and Porphyromonas gingivalis have been identified in atheromatous plaques of two patients suffering from atherosclerosis by PCR and fluorescence in situ hybridization (FISH). The use of the FISH technique suggested that these periodontopathic micro-organisms might be metabolically active within the wall of arteries, under the atherosclerotic lesion.
Cavrini
Francesca
F
Section of Microbiology, DMCSS, University of Bologna, Bologna, Italy 2Institut für Mikrobiologie und Hygiene, Charitè Universitätsmedizin, Berlin, Germany 3Department of Oral Sciences, University of Bologna, Bologna, Italy 4Department of Surgical Sciences, Anaesthesiology and Transplants, University of Bologna, Bologna, Italy 5Centro Regionale di Riferimento per le Emergenze Microbiologiche, Bologna, Italy.
Sambri
Vittorio
V
Section of Microbiology, DMCSS, University of Bologna, Bologna, Italy 2Institut für Mikrobiologie und Hygiene, Charitè Universitätsmedizin, Berlin, Germany 3Department of Oral Sciences, University of Bologna, Bologna, Italy 4Department of Surgical Sciences, Anaesthesiology and Transplants, University of Bologna, Bologna, Italy 5Centro Regionale di Riferimento per le Emergenze Microbiologiche, Bologna, Italy.
Moter
Annette
A
Section of Microbiology, DMCSS, University of Bologna, Bologna, Italy 2Institut für Mikrobiologie und Hygiene, Charitè Universitätsmedizin, Berlin, Germany 3Department of Oral Sciences, University of Bologna, Bologna, Italy 4Department of Surgical Sciences, Anaesthesiology and Transplants, University of Bologna, Bologna, Italy 5Centro Regionale di Riferimento per le Emergenze Microbiologiche, Bologna, Italy.
Servidio
Dora
D
Section of Microbiology, DMCSS, University of Bologna, Bologna, Italy 2Institut für Mikrobiologie und Hygiene, Charitè Universitätsmedizin, Berlin, Germany 3Department of Oral Sciences, University of Bologna, Bologna, Italy 4Department of Surgical Sciences, Anaesthesiology and Transplants, University of Bologna, Bologna, Italy 5Centro Regionale di Riferimento per le Emergenze Microbiologiche, Bologna, Italy.
Marangoni
Antonella
A
Section of Microbiology, DMCSS, University of Bologna, Bologna, Italy 2Institut für Mikrobiologie und Hygiene, Charitè Universitätsmedizin, Berlin, Germany 3Department of Oral Sciences, University of Bologna, Bologna, Italy 4Department of Surgical Sciences, Anaesthesiology and Transplants, University of Bologna, Bologna, Italy 5Centro Regionale di Riferimento per le Emergenze Microbiologiche, Bologna, Italy.
Montebugnoli
Lucio
L
Section of Microbiology, DMCSS, University of Bologna, Bologna, Italy 2Institut für Mikrobiologie und Hygiene, Charitè Universitätsmedizin, Berlin, Germany 3Department of Oral Sciences, University of Bologna, Bologna, Italy 4Department of Surgical Sciences, Anaesthesiology and Transplants, University of Bologna, Bologna, Italy 5Centro Regionale di Riferimento per le Emergenze Microbiologiche, Bologna, Italy.
Foschi
Federico
F
Section of Microbiology, DMCSS, University of Bologna, Bologna, Italy 2Institut für Mikrobiologie und Hygiene, Charitè Universitätsmedizin, Berlin, Germany 3Department of Oral Sciences, University of Bologna, Bologna, Italy 4Department of Surgical Sciences, Anaesthesiology and Transplants, University of Bologna, Bologna, Italy 5Centro Regionale di Riferimento per le Emergenze Microbiologiche, Bologna, Italy.
Prati
Carlo
C
Section of Microbiology, DMCSS, University of Bologna, Bologna, Italy 2Institut für Mikrobiologie und Hygiene, Charitè Universitätsmedizin, Berlin, Germany 3Department of Oral Sciences, University of Bologna, Bologna, Italy 4Department of Surgical Sciences, Anaesthesiology and Transplants, University of Bologna, Bologna, Italy 5Centro Regionale di Riferimento per le Emergenze Microbiologiche, Bologna, Italy.
Di Bartolomeo
Roberto
R
Section of Microbiology, DMCSS, University of Bologna, Bologna, Italy 2Institut für Mikrobiologie und Hygiene, Charitè Universitätsmedizin, Berlin, Germany 3Department of Oral Sciences, University of Bologna, Bologna, Italy 4Department of Surgical Sciences, Anaesthesiology and Transplants, University of Bologna, Bologna, Italy 5Centro Regionale di Riferimento per le Emergenze Microbiologiche, Bologna, Italy.
Cevenini
Roberto
R
Section of Microbiology, DMCSS, University of Bologna, Bologna, Italy 2Institut für Mikrobiologie und Hygiene, Charitè Universitätsmedizin, Berlin, Germany 3Department of Oral Sciences, University of Bologna, Bologna, Italy 4Department of Surgical Sciences, Anaesthesiology and Transplants, University of Bologna, Bologna, Italy 5Centro Regionale di Riferimento per le Emergenze Microbiologiche, Bologna, Italy.
D000368:Aged; D001011:Aorta / Q000382:microbiology; D001018:Aortic Diseases / Q000382:microbiology*; D001161:Arteriosclerosis / Q000382:microbiology*; D002339:Carotid Arteries / Q000382:microbiology; D002340:Carotid Artery Diseases / Q000382:microbiology*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D016133:Polymerase Chain Reaction; D016966:Porphyromonas gingivalis / Q000235:genetics / Q000302:isolation & purification*; D048373:Treponema denticola / Q000235:genetics / Q000302:isolation & purification*