title: Dosimetric characteristics of the new RadioCoil 103Pd wire line source for use in permanent brachytherapy implants.
abstract: Recently, a novel linear brachytherapy source in the form of a coiled wire has become available for use in interstitial implants of various treatment sites such as prostate gland. This source type employs a design completely different from that of most "seed" sources currently on the market, one which improves upon or eliminates several common problems with such sources. Dosimetric characteristics of these sources with active lengths 0.5 cm to 5.0 cm were determined for clinical application. For 0.5 cm and 1.0 cm active length sources, the dose rate constant, radial dose function, and two-dimensional (2D) anisotropy function were experimentally and theoretically determined following the updated AAPM Task Group 43 (TG-43U1) recommendations. Radial dose functions and/or "along-away" matrix functions were also obtained for sources with active lengths 2.0 cm to 5.0 cm. Measurements were performed with LiF thermoluminescent dosimeters in Solid Water phantoms. Measured data was compared to Monte Carlo simulated data in Solid Water utilizing the PTRAN code, version 7.43. After finding the data to be in agreement, Monte Carlo calculations were performed in liquid water to obtain clinically applicable dosimetric data as per TG-43U1 recommendations. The results indicated the dose rate constant of the 0.5 cm long RadioCoil 103Pd source in Solid Water to be 0.641 cGy h(-1) U(-1) when measured, and 0.636 cGy h(-1) U(-1) when simulated by Monte Carlo. The calculated dose rate constant in liquid water was found to be 0.650 cGy h(-1) U(-1). These values are comparable to other commercially available sources. Complete dosimetric data and simulation results are described in this paper. Per TG-43U1, clinical treatment planning systems should utilize the values reported for liquid water.
authors.affiliation: Department of Radiation Medicine, University of Kentucky Chandler Medical Center, Lexington, Kentucky 40536-0084, USA. alimeig@uky.edu
authors.forename: A S
authors.initials: AS
authors.lastname: Meigooni
authors.forename: H
authors.initials: H
authors.lastname: Zhang
authors.forename: J R
authors.initials: JR
authors.lastname: Clark
authors.forename: V
authors.initials: V
authors.lastname: Rachabatthula
authors.forename: R A
authors.initials: RA
authors.lastname: Koona
mesh_terms: D001822:Body Burden; D001918:Brachytherapy / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D008297:Male; D008954:Models, Biological; D009010:Monte Carlo Method; D009928:Organ Specificity; D010165:Palladium / Q000032:analysis / Q000627:therapeutic use*; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D019736:Prostheses and Implants; D011868:Radioisotopes / Q000032:analysis / Q000627:therapeutic use*; D011874:Radiometry / Q000379:methods*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D012062:Relative Biological Effectiveness
chemical_list: D011868:Radioisotopes; D010165:Palladium