Synthesis and stereochemistry of musacins isolated from Streptomyces griseoviridis(FH-S 1832).
Musacins E (1a), B(1)(2a) and B(2)(3a) have been synthesized starting from D-erythronolactone, L-tartaric acid and (S)-malic acid. The absolute stereochemistry of musacins was unambiguously established by this synthesis.
Ueki
Toshihiko
T
Department of Chemistry, Graduate School of Science, Osaka City University, Sumiyoshi-ku, Osaka, 558-8585, Japan.
Kinoshita
Takamasa
T
D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D013045:Species Specificity; D013237:Stereoisomerism; D013302:Streptomyces / Q000737:chemistry* / Q000145:classification
D007783:Lactones; C511830:musacin B1; C511831:musacin B2; C511832:musacin E