title: Highly enantioselective allylation of aldehydes catalyzed by indium(III)-PYBOX complex.
abstract: A chiral indium(III)-PYBOX complex prepared from indium triflate and chiral PYBOX has been discovered to effect high enantioselectivities in the addition of allyltributyl stannane to aldehydes. The allylation of a variety of aromatic, alpha,beta-unsaturated, and aliphatic aldehydes resulted in good yields and high enantioselectivities (up to 94% ee).
authors.affiliation: Department of Chemistry, National Unviversity of Singapore, 3 Science Drive 3, Singapore 117543.
authors.forename: Jun
authors.initials: J
authors.lastname: Lu
authors.forename: Shun-Jun
authors.initials: SJ
authors.lastname: Ji
authors.forename: Yong-Chua
authors.initials: YC
authors.lastname: Teo
authors.forename: Teck-Peng
authors.initials: TP
authors.lastname: Loh
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000498:Allyl Compounds / Q000737:chemistry*; D002384:Catalysis; D007204:Indium / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D010080:Oxazoles / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D000498:Allyl Compounds; D009942:Organometallic Compounds; D010080:Oxazoles; D011725:Pyridines; C510741:indium(III)-PYBOX; D007204:Indium