title: [The present and future of home care chemotherapy for patients with advanced and recurrent colorectal cancer].
abstract: OBJECTIVE
  If the chemotherapy at home is as effective as the chemotherapy at an outpatient clinic, QOL of the patients will be improved. In this paper the future of chemotherapy at home was clarified from the outcome of the chemotherapy for advanced and recurrent colorectal cancer.
  
  
  METHODS
  Hepatic arterial infusion chemotherapy (HAI) (5-FU 2,000 mg/w, continuous infusion for 7 days, n=123) for unresectable liver metastases and FL chemotherapy (5 FU 1,500 mg + l-LV 375 mg/w, continuous systemic chemotherapy for 7 days, n=32) for extra hepatic recurrence were carried out at home by a portable pump system every other week.
  
  
  RESULTS
  The response rates were 61.2% in HAI and 18.8% in FL. MST were 14.7 months in HAI and 10.8 months in FL. It was important to establish a surveillance network system to continue the chemotherapy at home.
  
  
  CONCLUSIONS
  It was suggested that the chemotherapy at home was effective and to maintain the patient's QOL as one of the options.
authors.affiliation: Dept. of Surgery, Tokyo Metropolitan Komagome Hospital.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Takahashi
authors.forename: Takeo
authors.initials: T
authors.lastname: Mori
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsumoto
authors.forename: Hidenori
authors.initials: H
authors.lastname: Miyamoto
authors.forename: Kuniyoshi
authors.initials: K
authors.lastname: Arai
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Iwasaki
authors.forename: Sou
authors.initials: S
authors.lastname: Katayanagi
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage; D006499:Hepatic Artery; D018718:Home Infusion Therapy / Q000639:trends*; D006801:Humans; D007261:Infusions, Intra-Arterial; D002955:Leucovorin / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000556:secondary; D011379:Prognosis; D011788:Quality of Life; D015996:Survival Rate
chemical_list: D002955:Leucovorin; D005472:Fluorouracil