title: Spinal epidural abscess: an analysis of 24 cases.
abstract: BACKGROUND
  Despite advances in neuroimaging and neurosurgical care, spinal abscess remains a challenging problem with mortality rates ranging from 4.6% to 31% in recent series.
  
  
  METHODS
  Between January 1986 and December 2003, 24 patients with spinal epidural abscess were treated. Seventeen were men and 7 were women at the average age of 47.5 years. Concurrent illnesses that result in immunodepression such as diabetes and infections occurred in 62% of the case patients. All patients had back pain, 16 had muscle weakness, 9 had paresthesias, and 8 had sphincteral changes. Twenty-one patients underwent surgical procedures. In 11 case patients, the abscess had a frankly purulent material, and, in 5, the epidural lesion consisted of granulation tissue; the other 5 case patients had a combination of the 2. Three patients were treated conservatively. Staphylococcus aureus was isolated in 57% of the case patients. The lumbar spine was affected in 11 patients; the cervical spine, in 3.
  
  
  RESULTS
  Fifteen patients recovered their normal neurological functions but 4 remained with some neurological disability. No deaths occurred in this series.
  
  
  CONCLUSIONS
  Immediate surgical drainage of the abscess, before the development of severe neurological deficit, combined with specific antibiotics remains the treatment of choice.
authors.affiliation: Department of Neurosurgery, Servidores do Estado Hospital (HSE), Rio de Janeiro, 20221-903 Brazil.
authors.forename: Celestino Esteves
authors.initials: CE
authors.lastname: Pereira
authors.forename: José Carlos
authors.initials: JC
authors.lastname: Lynch
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001416:Back Pain / Q000382:microbiology; D015984:Causality; D020802:Epidural Abscess / Q000382:microbiology / Q000503:physiopathology* / Q000628:therapy*; D004824:Epidural Space / Q000382:microbiology / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology; D007796:Laminectomy / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D018908:Muscle Weakness / Q000382:microbiology; D010292:Paresthesia / Q000382:microbiology; D012189:Retrospective Studies; D013116:Spinal Cord / Q000503:physiopathology; D013203:Staphylococcal Infections / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy*; D016896:Treatment Outcome; D014549:Urinary Incontinence / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents