title: Effect of iron absorption on plasma membrane proteins of small intestinal mucosal cells from iron-deficient rats.
abstract: Plasma membrane protein was isolated from small intestinal mucosal cells of normal and iron-deficient rats during iron absorption and examined by acrylamide gel electrophoresis. Two proteins were present in increased amounts in the iron-deficient animals 10 min after administration of iron; uptake studies with 3H-leucine indicated that each had been newly-synthesized. The molecular weights of the proteins were about 60,000 and 300,000.
authors.affiliation: Department of Pathology, Queen's University and Kingston General Hospital, Kingston, Ontario, Canada.
authors.forename: N
authors.initials: N
authors.lastname: Kaufman
authors.forename: M
authors.initials: M
authors.lastname: Newkirk
authors.forename: J C
authors.initials: JC
authors.lastname: Wyllie
mesh_terms: D000821:Animal Feed; D000818:Animals; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D007413:Intestinal Mucosa / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism*; D007421:Intestine, Small / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism*; D007501:Iron / Q000378:metabolism / Q000494:pharmacology*; D000090463:Iron Deficiencies; D008565:Membrane Proteins / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D008565:Membrane Proteins; D007501:Iron