The effects of Hochu-ekki-to in patients with atopic dermatitis resistant to conventional treatment.
Hochu-ekki-to is one of Kampo formulas containing Astragalus root, liquorice, jujube, ginseng, white Atractylodes rhizome, fresh ginger and Chinese angelica root. This formula has been identified as an effective drug to improve the function of digestive systems and to strengthen defensive systems against many kinds of infections. We examined serum IgE levels and eosinophils before and after the administration of Hochu-ekki-to in patients with recalcitrant atopic dermatitis. The increased numbers of eosinophils was statistically decreased after 3 months' use of this formula. Serum IgE levels showed a tendency to decrease after the administration of this substance.
Kobayashi
H
H
Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan. hiromik@med.osaka-cu.ac.jp
Mizuno
N
N
Teramae
H
H
Kutsuna
H
H
Ueoku
S
S
Onoyama
J
J
Yamanaka
K
K
Fujita
N
N
Ishii
M
M
D000293:Adolescent; D000328:Adult; D003876:Dermatitis, Atopic / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004804:Eosinophils / Q000187:drug effects; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007962:Leukocytes / Q000187:drug effects; D008297:Male
D004365:Drugs, Chinese Herbal; D007166:Immunosuppressive Agents; C402943:bu-zhong-yi-qi-tang