title: The effects of trauma recall on smoking topography in posttraumatic stress disorder and non-posttraumatic stress disorder trauma survivors.
abstract: Smoking topography was measured in trauma survivors with and without posttraumatic stress disorder (PTSD) after recalling trauma-related and neutral experiences. Analysis of covariance was performed on puff topography and mood measures using nicotine dependence scores and current major depressive disorder as covariates. Puff volumes were higher in the PTSD group than in the non-PTSD group. The PTSD group exhibited stable puff onset intervals while the non-PTSD group exhibited significantly shorter intervals following trauma recall. These findings support a "ceiling effect" hypothesis in which individuals with PTSD perpetually smoke in such a way as to maximize nicotine delivery, possibly reducing the potentially reinforcing effects of increased smoke delivery in negative affect-inducing situations.
authors.affiliation: Duke University Medical Center, Durham, NC, USA.
authors.forename: F Joseph
authors.initials: FJ
authors.lastname: McClernon
authors.forename: Jean C
authors.initials: JC
authors.lastname: Beckham
authors.forename: Susannah L
authors.initials: SL
authors.lastname: Mozley
authors.forename: Michelle E
authors.initials: ME
authors.lastname: Feldman
authors.forename: Scott R
authors.initials: SR
authors.lastname: Vrana
authors.forename: Jed E
authors.initials: JE
authors.lastname: Rose
mesh_terms: D000328:Adult; D001007:Anxiety / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D011939:Mental Recall; D012737:Sex Factors; D012907:Smoking / Q000523:psychology*; D013313:Stress Disorders, Post-Traumatic / Q000523:psychology*; D017741:Survivors / Q000523:psychology*; D014947:Wounds and Injuries / Q000523:psychology*