title: Psychometric validation of the French version of the quality of life in epilepsy inventory (QOLIE-31): comparison with a generic health-related quality of life questionnaire.
abstract: A psychometric evaluation of a French transcultural version of the quality of life in epilepsy inventory-31 (QOLIE-31) was carried out. QOLIE-31 was compared to a generic health-related quality of life questionnaire, the Nottingham health profile (NHP). The psychometric properties of QOLIE-31, assessed in 190 adults with epilepsy, included: acceptability, test-retest reliability and validity (multi-trait analysis including internal consistency and item-to-scale correlations, construct validity using factor analysis, discriminative validity using relationship with disease characteristics, treatment effects, divergent and convergent validity using correlations with NHP scores). Both acceptability and reproducibility were good and internal consistency was high (Cronbach's alpha coefficient = 0.86). Factor analysis with varimax rotation identified seven factors with eigenvalues > 1, with two factors, related to cognitive function and mood, accounting for 46.5% of the variance. However, goodness of fit indices revealed that a model with four factors best fitted the data. The first factor corresponds to a generic mental dimension, the second is equivalent to the cognitive functioning dimension, the third to medication effects including social functioning, and the fourth to seizure worry. Discriminative validity was good for seizure control and treatment tolerability. High correlations between QOLIE-31 and pertinent NHP scales (emotional reactions, energy and social isolation) were observed. The French version of QOLIE-31 thus meets established psychometric criteria for reliability and validity.
authors.affiliation: Unit of Clinical Research and Epidemiology, University Hospital of Montpellier, France. mc-picot@chu-montpellier.fr
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Picot
authors.forename: Arielle
authors.initials: A
authors.lastname: Crespel
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Daurès
authors.forename: Michel
authors.initials: M
authors.lastname: Baldy-Moulinier
authors.forename: Abdelkader
authors.initials: A
authors.lastname: El Hasnaoui
mesh_terms: D000203:Activities of Daily Living / Q000145:classification / Q000523:psychology; D000223:Adaptation, Psychological; D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use; D003431:Cross-Cultural Comparison; D004827:Epilepsy / Q000188:drug therapy / Q000523:psychology*; D005260:Female; D005602:France; D006801:Humans; D007802:Language; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D011594:Psychometrics / Q000706:statistics & numerical data; D011788:Quality of Life / Q000523:psychology*; D015203:Reproducibility of Results; D012803:Sick Role; D018434:Sickness Impact Profile; D013223:Statistics as Topic; D011795:Surveys and Questionnaires; D014481:United States
chemical_list: D000927:Anticonvulsants