Inhibition of E. coli beta-hydroxydecanoyl thioester dehydrase by ppGpp.
Guanosine-5'-diphosphate-3'-diphosphate was found to inhibit beta-hydroxydecanoyl thioester dehydrase of E. coli at concentrations corresponding to those generated in vivo during amino acid starvation of rel+ cells.
Stein
J P
JP
James Bryant Conant Laboratory, Harvard University, Cambridge, Massachusetts 02138, USA.
Bloch
K E
KE
D004791:Enzyme Inhibitors / Q000494:pharmacology*; D004926:Escherichia coli / Q000201:enzymology*; D054889:Fatty Acid Synthase, Type II; D006159:Guanosine Tetraphosphate / Q000494:pharmacology*; D006836:Hydro-Lyases / Q000037:antagonists & inhibitors* / Q000378:metabolism
D004791:Enzyme Inhibitors; D006159:Guanosine Tetraphosphate; D006836:Hydro-Lyases; C047118:3-hydroxyacyl-(acyl-carrier-protein) dehydratase; D054889:Fatty Acid Synthase, Type II