Topical tacrolimus in alopecia areata.
Eleven patients with alopecia areata affecting 10% to 75% of the scalp, average duration 6 years, had no terminal hair growth in response to tacrolimus ointment 0.1% applied twice daily for 24 weeks. Treatment failure may reflect insufficient depth of penetration of the ointment formulation and less than optimal patient selection.
Price
Vera H
VH
Department of Dermatology, University of California at San Francisco Hair Research Center, 94117, USA. pricev@derm.ucsf.edu
Willey
Andrea
A
Chen
Bryan K
BK
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000506:Alopecia Areata / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009824:Ointments; D016559:Tacrolimus / Q000008:administration & dosage*
D007166:Immunosuppressive Agents; D009824:Ointments; D016559:Tacrolimus