[Pathological analysis of breast carcinoma after silicone gel injection].
OBJECTIVE
To explore the correlation between breast carcinoma and silicone gel injection for breast augmentation.


METHODS
Four cases of breast cancer after silicone gel injection were studied by means of clinical pathological analysis.


RESULTS
In the four women, breast lump of over 5 cm in diameter was found half year to 2 years after silicone injection. The tumor was misdiagnosed to inflammatory reaction of silicone gel injection. Definite diagnosis was made by histological examinations, which showed there was mucoid, light blue and well-distributed silicone gel among the nests of neoplasm cells. Lymph node metastasis of cancer cells was observed.


CONCLUSIONS
Silicone gel injection to the breast may be a reason for evoking or accelerating breast cancer. Breast cancer that occurred after breast augmentation with silicone gel injection could be misdiagnosed. Final diagnosis depends on biopsy. Silicone gel injection for breast augmentation should be abandoned.
Chen
Guo-qin
GQ
Department of Pathology, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China.
Liu
Rong
R
Gu
Ying-ying
YY
D000328:Adult; D001940:Breast / Q000473:pathology / Q000601:surgery; D001943:Breast Neoplasms / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016462:Mammaplasty / Q000009:adverse effects*; D008875:Middle Aged; D020034:Silicone Gels / Q000009:adverse effects* / Q000627:therapeutic use
D020034:Silicone Gels