Postirradiation sarcoma: a case report and current review.
Irradiation-induced sarcomas are well-known potential late sequelae of radiation therapy. These tumors are very aggressive and often elude early detection and timely intervention, rapidly leading to early demise of afflicted patients. Long-term patient follow-up and a high index of suspicion are crucial for timely intervention. In this report, we present a case of irradiation-induced osteosarcoma involving the mandible. Diagnostic and therapeutic considerations are subsequently discussed.
Maghami
Ellie G
EG
Division of Head and Neck Surgery, UCLA School of Medicine, Los Angeles, CA 90095-1624, USA.
St-John
Maie
M
Bhuta
Sunita
S
Abemayor
Elliot
E
D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D002277:Carcinoma / Q000532:radiotherapy; D006801:Humans; D008297:Male; D008334:Mandible / Q000528:radiation effects / Q000601:surgery; D008339:Mandibular Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D012516:Osteosarcoma / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D014067:Tonsillar Neoplasms / Q000532:radiotherapy; D016896:Treatment Outcome