Combining two-directional synthesis and tandem reactions: synthesis of trioxadispiroketals.
A tandem bromonium ion-promoted cyclization of two pendant hydroxyl groups onto a central furan core provides a highly direct route to both the [5,5,5]- and the [6,5,6]-trioxadispiroketal ring systems.
McDermott
Paul J
PJ
School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich, NR4 7TJ, UK.
Stockman
Robert A
RA
D013141:Spiro Compounds / Q000138:chemical synthesis*
D013141:Spiro Compounds