Experimental muscle pain increases mechanomyographic signal activity during sub-maximal isometric contractions.
This study was designed to investigate the local effect of experimental muscle pain on the MMG and the surface EMG during a range of sub-maximal isometric contractions. Muscle pain was induced by injections of hypertonic saline into the biceps brachii muscle in 12 subjects. Injections of isotonic saline served as a control. Pain intensity and location, MMG and surface EMG from the biceps brachii were assessed during static isometric (0%, 10%, 30%, 50% and, 70% of the maximal voluntary contraction) and ramp isometric (0-50% of the maximal voluntary contraction) elbow flexions. MMG and surface EMG signals were analyzed in the time and frequency domain. Experimentally induced muscle pain induced an increase in root mean square values of the MMG signal while no changes were observed in the surface EMG. Most likely this increase reflects changes in the mechanical contractile properties of the muscle and indicates compensatory mechanisms, i.e. decreased firing rate and increased twitch force to maintain a constant force output in presence of experimental muscle pain. Under well-controlled conditions, MMG recordings may be more sensitive than surface EMG recordings and clinically useful for detecting non-invasively increased muscle mechanical contributions during muscle pain conditions.
Madeleine
P
P
Center for Sensory-Motor Interaction, Department of Health Science and Technology, Aalborg University, Building D-3, Fredrik Bajers Vej 7, DK-9220 Aalborg, Denmark. pm@ist.auc.dk
Arendt-Nielsen
L
L
D000222:Adaptation, Physiological; D000328:Adult; D001132:Arm / Q000503:physiopathology; D006801:Humans; D007273:Injections, Intramuscular; D007537:Isometric Contraction / Q000502:physiology*; D008297:Male; D008954:Models, Biological; D018482:Muscle, Skeletal / Q000503:physiopathology*; D009213:Myography; D010146:Pain / Q000503:physiopathology*; D010147:Pain Measurement; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage; D012815:Signal Processing, Computer-Assisted
D012462:Saline Solution, Hypertonic