Early white matter changes in Wilson disease.
We describe a 12 years old male who presented with one year history of cognitive decline with extrapyramidal features. Wilson disease was diagnosed on basis of biochemical studies and MRI. MRI showed increased signal intensity on T2 weighted images in basal ganglia and supratentorial with infratentorial gray and white matter. Our patient developed white matter changes early in course of disease.
Verma
Archana
A
Department of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi-2.
Singh
N N
NN
Misra
S
S
D001921:Brain / Q000473:pathology*; D002648:Child; D003072:Cognition Disorders / Q000209:etiology; D006527:Hepatolenticular Degeneration / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male