Preliminary evidence for the presence of glutathione-s-transferase activity in mammalian and avian brain.
Glutathione-S-transferase activity has been demonstrated in the brain of rabbit, guinea pig, rat, mouse, and pigeon. The activity was in the following order: rabbit > (guinea pig = mouse) > rat > pigeon. The activity of brain was about 1/3 to 1/9 of that present in liver depending upon the species. In the rat brain glutathione-S-transferase activity was found to be distributed equally in cerebrum, cerebellum, and brain stem and localized mainly in the organelle-free cytosol fraction.
Dixit
R
R
Industrial Toxicology Research Centre, Mahatma Gandhi Marg, Lucknow, India.
Mukhtar
H
H
Seth
P K
PK
Murti
C R
CR
D000818:Animals; D001921:Brain / Q000201:enzymology*; D010856:Columbidae; D003600:Cytosol / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism*; D006168:Guinea Pigs; D051379:Mice; D011817:Rabbits; D051381:Rats; D013347:Subcellular Fractions / Q000201:enzymology
D005982:Glutathione Transferase