Breast cancer in African-American women.
African-American women face a lower risk of being diagnosed with breast cancer as compared to Caucasian-American women, yet they paradoxically face an increased breast cancer mortality hazard. An increased incidence rate for early-onset disease has also been documented. This manuscript review summarizes the socioeconomic, environmental, genetic, and possible primary tumor biologic factors that may explain these disparities.
Newman
Lisa A
LA
Breast Care Center, University of Michigan, 1500 East Medical Center Drive, 3308 CGC, Ann Arbor, Michigan 48109, USA. lanewman@umich.edu
D001741:Black or African American; D001943:Breast Neoplasms / Q000209:etiology* / Q000235:genetics / Q000401:mortality* / Q000628:therapy; D004777:Environment; D005260:Female; D020022:Genetic Predisposition to Disease; D006297:Health Services Accessibility; D006801:Humans; D015994:Incidence; D011787:Quality of Health Care; D012923:Social Class