title: The bone-metal interface of defect and press-fit ingrowth of microwave plasma-chemical vapor deposition implants in the rabbit model.
abstract: OBJECTIVE
  The histological differences between the defect and contact areas of the implant surface to bone were tested in 35 New Zealand White rabbits in a standardized model. Microwave plasma chemical vapor-coated implant probes were tested in control and uncoated materials.
  
  
  METHODS
  In each femur of 35 rabbits, cylindrical implant rods with a planed side were inserted. Three groups, divided in coated and uncoated material at half, were observed 42, 84 and 168 days. The probes were examined histologically for bone-implant contact in the curved and plane (defect area) sides.
  
  
  RESULTS
  Generally the bone-implant contact seems to be nearly constant in time in the curved area of coated and uncoated probes. Here the implant was inserted in the press-fit mode. Diamond-coated probes showed similar bone-implant contact (51.9% (42 days), 62.5% (84 days), 56.1% (168 days)) compared to uncoated material (56.2%, 65.4%, 62.9%). The defect area (plane side) had no bone-implant contact at the time of insertion and showed increasing values on longer observation times with only significant differences in the 42-day group between coated (17.85%, 35.2%, 47.7%) and uncoated materials (35.5%, 40.55%, 51.81%).
  
  
  CONCLUSIONS
  The evaluation of the curved side of the implant probe showed no great variation of bone-implant contact within the described observation times. This model simulates the usual implant insertion situation. The diamond-coated material becomes osseointegrated at a later time point. The bone-implant contact was only statistically relevant in one group in comparison to uncoated material.
authors.affiliation: Department of Oral & Cranio-Maxillofacial Surgery, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany. stephan.rupprecht@mkg.imed.uni-erlangen.de
authors.forename: Stephan
authors.initials: S
authors.lastname: Rupprecht
authors.forename: Alexandra
authors.initials: A
authors.lastname: Bloch-Birkholz
authors.forename: Bernd
authors.initials: B
authors.lastname: Lethaus
authors.forename: Stefan
authors.initials: S
authors.lastname: Rosiwal
authors.forename: Friedrich Wilhelm
authors.initials: FW
authors.lastname: Neukam
authors.forename: Andreas
authors.initials: A
authors.lastname: Schlegel
mesh_terms: D000497:Alloys; D000818:Animals; D017554:Carbon Compounds, Inorganic; D020099:Coated Materials, Biocompatible; D018130:Diamond; D005260:Female; D005269:Femur; D020007:Implants, Experimental; D008422:Materials Testing; D008670:Metals; D008872:Microwaves; D023421:Models, Animal; D016348:Osseointegration; D019919:Prosthesis Implantation / Q000379:methods; D011817:Rabbits; D017655:Silicon Compounds; D013997:Time Factors; D014025:Titanium
chemical_list: D000497:Alloys; D017554:Carbon Compounds, Inorganic; D020099:Coated Materials, Biocompatible; D008670:Metals; D017655:Silicon Compounds; C031462:titanium alloy (TiAl6V4); D018130:Diamond; D014025:Titanium; C022088:silicon carbide