Age-dependent decreases of sulfur and magnesium in human round ligaments of the uterus and relationships among elements.
To elucidate the compositional change of ligaments with aging, the authors investigated both age-related changes of elements and relationships among elements in the round ligaments of the uterus (round ligaments) by inductively coupled plasma-atomic emission spectrometry. The bilateral round ligaments were resected from 20 cadavers and also from the uteri removed surgically from 11 patients bearing uterine myoma or cancer. Thirty-one subjects ranged in age from 34 to 92 yr. It was found that both S and Mg decreased gradually in the round ligaments with aging, but Ca, P, Zn, Fe, and Al did not change significantly with aging. Regarding the relationships among elements, very significant direct correlations were found among the contents of Ca, P, S, and Mg in the round ligaments, whereas significant inverse correlations were found between the contents of Zn and elements, such as Ca, P, S, and Mg. It should be noted that there was an extremely significant direct correlation between Ca and P contents in the round ligaments.
Naganuma
Takashi
T
Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Nara 634-8521, Japan.
Naruse
Katsuhiko
K
Tohno
Yoshiyuki
Y
Tohno
Setsuko
S
Yamasaki
Mineo
M
Minami
Takeshi
T
Moriwake
Yumi
Y
Morikawa
Hajime
H
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism*; D000535:Aluminum / Q000378:metabolism; D002118:Calcium / Q000378:metabolism; D005260:Female; D006801:Humans; D007501:Iron / Q000378:metabolism; D008274:Magnesium / Q000378:metabolism*; D008875:Middle Aged; D010758:Phosphorus / Q000378:metabolism; D012404:Round Ligament of Uterus / Q000378:metabolism*; D013054:Spectrophotometry, Atomic; D013455:Sulfur / Q000378:metabolism*; D015032:Zinc / Q000378:metabolism
D010758:Phosphorus; D013455:Sulfur; D000535:Aluminum; D007501:Iron; D008274:Magnesium; D015032:Zinc; D002118:Calcium