title: GOAnno: GO annotation based on multiple alignment.
abstract: GOAnno is a web tool that automatically annotates proteins according to the Gene Ontology (GO) using evolutionary information available in hierarchized multiple alignments. GO terms present in the aligned functional subfamily can be cross-validated and propagated to obtain highly reliable predicted GO annotation based on the GOAnno algorithm.
  
  
  BACKGROUND
  The web tool and a reduced version for local installation are freely available at http://igbmc.u-strasbg.fr/GOAnno/GOAnno.html
  
  
  BACKGROUND
  The website supplies a detailed explanation and illustration of the algorithm at http://igbmc.u-strasbg.fr/GOAnno/GOAnnoHelp.html.
authors.affiliation: Laboratoire de Biologie et Génomique Structurales, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP BP 163, Illkirch , France. chalmel@igbmc.u-strasbg.fr
authors.forename: F
authors.initials: F
authors.lastname: Chalmel
authors.forename: A
authors.initials: A
authors.lastname: Lardenois
authors.forename: J D
authors.initials: JD
authors.lastname: Thompson
authors.forename: J
authors.initials: J
authors.lastname: Muller
authors.forename: J-A
authors.initials: JA
authors.lastname: Sahel
authors.forename: T
authors.initials: T
authors.lastname: Léveillard
authors.forename: O
authors.initials: O
authors.lastname: Poch
mesh_terms: D000465:Algorithms; D030562:Databases, Protein; D004282:Documentation / Q000379:methods*; D020407:Internet; D011506:Proteins / Q000737:chemistry* / Q000145:classification*; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software; D014584:User-Computer Interface
chemical_list: D011506:Proteins