title: [Research progress and prospect of animal gene targeting].
abstract: Established upon the embryo stem cell technique and homologous recombination, gene targeting has been widely used in the genome specific manipulation, especially applied in the genetic trait modification of transgenic animal. Our paper reviewed the history of transgenic animal, somatic cloning and gene targeting, which indicates the influence towards the current status and prospect of the transgenic animal production.
authors.affiliation: National Laboratory for Agrobiotechnology, China Agricultural University, Beijing 100094, China.
authors.forename: Xiang-Ping
authors.initials: XP
authors.lastname: Li
authors.forename: Wei-Zhuo
authors.initials: WZ
authors.lastname: Xu
authors.forename: Ning
authors.initials: N
authors.lastname: Li