Determinants of IV heparin treatment in patients with ischemic stroke.
Management of acute ischemic stroke with IV unfractionated heparin is subject to debate. The authors evaluated patient-related and institutional factors influencing its use in 42 hospitals. Cardioembolic stroke type, carotid stenosis, atrial fibrillation, and treatment in stroke units or intensive care units significantly increased the probability of use. However, there are large unexplained variations in IV heparin use among hospitals.
Schmidt
W-P
WP
Institute of Epidemiology and Social Medicine, University of Muenster, Muenster, Germany.
Heuschmann
P
P
Taeger
D
D
Henningsen
H
H
Buecker-Nott
H-J
HJ
Berger
K
K
D000208:Acute Disease; D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000150:complications / Q000453:epidemiology; D002545:Brain Ischemia / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D016893:Carotid Stenosis / Q000150:complications; D015897:Comorbidity; D048909:Diabetes Complications / Q000188:drug therapy / Q000453:epidemiology; D005260:Female; D005858:Germany / Q000453:epidemiology; D019983:Guideline Adherence / Q000706:statistics & numerical data*; D006331:Heart Diseases / Q000150:complications; D006493:Heparin / Q000008:administration & dosage / Q000627:therapeutic use*; D006757:Hospital Units / Q000706:statistics & numerical data; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000453:epidemiology; D007262:Infusions, Intravenous; D007362:Intensive Care Units / Q000706:statistics & numerical data; D020766:Intracranial Embolism / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology; D008297:Male; D008875:Middle Aged; D016134:Organizational Policy; D017410:Practice Guidelines as Topic; D012008:Recurrence; D012042:Registries
D000925:Anticoagulants; D006493:Heparin