title: A chewing gum containing 7.5% sodium hexametaphosphate inhibits stain deposition compared with a placebo chewing gum.
abstract: The 2-period, randomized, double-blind, placebo-controlled, crossover study compared the stain-prevention and stain-removal benefit of a chewing gum containing 7.5% sodium hexametaphosphate (measured by digital image analysis) with a placebo chewing gum. The results of this study support that sodium hexametaphosphate delivered from a chewing gum prevents dental stain formation and facilitates stain removal, which leads to a perceptible whitening benefit. The long-term clinical benefits of sodium hexametaphosphate delivered from chewing gum have not been reported in the literature.
authors.affiliation: The Procter & Gamble Company, Health Care Research Center, Mason, Ohio, USA.
authors.forename: Aaron R
authors.initials: AR
authors.lastname: Biesbrock
authors.forename: Patricia
authors.initials: P
authors.lastname: Walters
authors.forename: Robert D
authors.initials: RD
authors.lastname: Bartizek
mesh_terms: D000328:Adult; D000891:Anti-Infective Agents, Local / Q000009:adverse effects; D002638:Chewing Gum / Q000032:analysis; D002710:Chlorhexidine / Q000009:adverse effects; D003116:Color; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000008:administration & dosage*; D023861:Photography, Dental; D010919:Placebos; D013662:Tea / Q000009:adverse effects; D014070:Tooth / Q000473:pathology; D014073:Tooth Bleaching; D014075:Tooth Discoloration / Q000473:pathology / Q000517:prevention & control*
chemical_list: D000891:Anti-Infective Agents, Local; D002638:Chewing Gum; D010710:Phosphates; D010919:Placebos; D013662:Tea; C009285:sodium polymetaphosphate; D002710:Chlorhexidine