title: Measurement of left ventricular velocities: phase contrast MRI velocity mapping versus tissue-doppler-ultrasound in healthy volunteers.
abstract: The aim of this study was the comparison of phase contrast magnetic resonance imaging (PCMRI) measurements of left ventricular velocities in a physiological in vivo setting with tissue-Doppler-ultrasound (tissue Doppler imaging: TDI) data in healthy volunteers. Images were acquired in short axis view using a flow compensated black blood k-space segmented gradient echo sequence. Velocity encoding was performed by adding a bipolar gradient after each rf-pulse to the otherwise identical pulse sequences. Full in-plane velocity information of the moving heart was obtained in 16 heartbeats within one breath-hold measurement. Twenty-nine healthy volunteers (mean age=25 years) were examined with both imaging modalities. Both PCMRI and TDI demonstrate a biphasic profile of radial velocities over the cardiac cycle. Intraindividual comparison of left ventricular velocity data acquired using PCMRI and TDI show a very good correspondence with r-values of 0.97. The in vivo study in 29 healthy volunteers demonstrates a high validity of time-resolved phase contrast measurements for the analysis of left ventricular myocardial velocities.
authors.affiliation: Department of Radiology, Section of Medical Physics, University of Freiburg, Freiburg, Germany. bernd.jung@uniklinik-freiburg.de
authors.forename: Bernd
authors.initials: B
authors.lastname: Jung
authors.forename: Britta
authors.initials: B
authors.lastname: Schneider
authors.forename: Michael
authors.initials: M
authors.lastname: Markl
authors.forename: Bernward
authors.initials: B
authors.lastname: Saurbier
authors.forename: Annette
authors.initials: A
authors.lastname: Geibel
authors.forename: Juergen
authors.initials: J
authors.lastname: Hennig
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity; D003287:Contrast Media / Q000008:administration & dosage; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D015588:Observer Variation; D010210:Papillary Muscles / Q000000981:diagnostic imaging / Q000502:physiology; D012016:Reference Values; D018608:Ultrasonography, Doppler; D014664:Vasodilation / Q000502:physiology; D016276:Ventricular Function; D016277:Ventricular Function, Left / Q000502:physiology
chemical_list: D003287:Contrast Media