Malignant myoepithelioma of the salivary gland--an untypical clinical course.
A case of malignant tumor developing from myoepithelial cells (malignant myoepithelioma) is presented. The primary focus was located in the region of the left submandibular salivary gland. A relapse and metastases were disclosed in the same salivary gland, in the lung and the left breast. Immunohistochemical studies demonstrated positive reactions for S-100 protein, cytokeratins, smooth muscle actin, vimentin, GFAP protein, p53 protein and Ki-67 antigen, and allowed for establishing the final histopathological diagnosis of malignant myoepithelioma.
Rzeszutko
Wojciech
W
Department of Pathomorphology, Lower Silesia Center of Oncology, Wrocław.
Kasprzak
Piotr
P
Dziegiel
Piotr
P
Rzeszutko
Marta
M
Sopel
Mirosław
M
D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001943:Breast Neoplasms / Q000556:secondary / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009208:Myoepithelioma / Q000737:chemistry / Q000556:secondary* / Q000601:surgery; D009364:Neoplasm Recurrence, Local; D013365:Submandibular Gland Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery
D014408:Biomarkers, Tumor