title: The effects of different mesh generation methods on computational fluid dynamic analysis and power loss assessment in total cavopulmonary connection.
abstract: The flow field and energetic efficiency of total cavopulmonary connection (TCPC) models have been studied by both in vitro experiment and computational fluid dynamics (CFD). All the previous CFD studies have employed the structured mesh generation method to create the TCPC simulation model. In this study, a realistic TCPC model with complete anatomical features was numerically simulated using both structured and unstructured mesh generation methods. The flow fields and energy losses were compared in these two meshes. Two different energy loss calculation methods, the control volume and viscous dissipation methods, were investigated. The energy losses were also compared to the in vitro experimental results. The results demonstrated that: (1) the flow fields in the structured model were qualitatively similar to the unstructured model; (2) more vortices were present in the structured model than in the unstructured model; (3) both models had the least energy loss when flow was equally distributed to the left and right pulmonary arteries, while high losses occurred for extreme pulmonary arterial flow splits; (4) the energy loss results calculated using the same method were significantly different for different meshes; and (5) the energy loss results calculated using different methods were significantly different for the same mesh.
authors.affiliation: Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA.
authors.forename: Yutong
authors.initials: Y
authors.lastname: Liu
authors.forename: Kerem
authors.initials: K
authors.lastname: Pekkan
authors.forename: S Casey
authors.initials: SC
authors.lastname: Jones
authors.forename: Ajit P
authors.initials: AP
authors.lastname: Yoganathan
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D003198:Computer Simulation; D020342:Finite Element Analysis; D018610:Heart Bypass, Right / Q000379:methods*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008955:Models, Cardiovascular; D011651:Pulmonary Artery / Q000502:physiology* / Q000601:surgery*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014684:Venae Cavae / Q000503:physiopathology* / Q000601:surgery*