title: Hearing loss and extent of labyrinthine injury in Pseudomonas otitis media.
abstract: OBJECTIVE
  To determine if the severity of hearing loss due to semicircular canal transection (SCT) in Pseudomonas otitis media (POM) is a function of the extent of the labyrinthine injury.
  
  
  METHODS
  POM was induced bilaterally in 45 guinea pigs. After 2 to 4 days, SCT was performed in one 1 on the horizontal canal, the superior canal, or both the horizontal and the superior canals. Auditory-evoked brainstem responses were measured before and after SCT.
  
  
  RESULTS
  POM was induced bilaterally in all animals. Elevation of click thresholds was found in almost all SCT ears of all 3 groups; however, there were no significant differences between groups. Comparing the SCT ear to the contralateral, control ear, mean hearing losses in the horizontal, superior, and horizontal + superior SCT groups were 23 dB, 27 dB, and 24 dB, respectively.
  
  
  CONCLUSIONS
  Hearing loss does not correlate with extent of labyrinthine injury in POM in the guinea pig.
  
  
  METHODS
  B-2.
authors.affiliation: Department of Otolaryngology, University of Florida, Gainesville 32610-0264, USA.
authors.forename: John
authors.initials: J
authors.lastname: Malaty
authors.forename: James C
authors.initials: JC
authors.lastname: Lee
authors.forename: Mei
authors.initials: M
authors.lastname: Zhang
authors.forename: Gary
authors.initials: G
authors.lastname: Stevens
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Antonelli
mesh_terms: D000818:Animals; D005260:Female; D006168:Guinea Pigs; D034381:Hearing Loss / Q000209:etiology*; D015601:Injury Severity Score; D008297:Male; D010033:Otitis Media / Q000150:complications / Q000382:microbiology*; D011552:Pseudomonas Infections / Q000150:complications*; D012665:Semicircular Canals / Q000293:injuries*