title: CADASIL in a family from north-west India.
abstract: We here with report a family with two sibs having history of recurrent familial stroke. Neuroimaging revealed diffuse hyperintense signals in subcortical white matter and basal ganglia on MR images in younger sib suggestive of cerebral autosomal dominant arteriopathy with sub-cortical infarcts and leucoencephalopathy (CADASIL). The diagnosis was further strengthened on skin biopsy showing presence of PAS positive granules with thickening of dermal vessels.
authors.affiliation: Department of Neurology; SMS Medical College and Hospital, Jaipur 302 004, Rajasthan.
authors.forename: A
authors.initials: A
authors.lastname: Panagariya
authors.forename: Bhawana
authors.initials: B
authors.lastname: Sharma
authors.lastname: Shubhakaran
mesh_terms: D001921:Brain / Q000473:pathology; D046589:CADASIL / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D007194:India; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged