Effects of phytoncides on blood pressure under restraint stress in SHRSP.
1. Phytoncides are volatile substances released mainly from trees. We studied whether phytoncides can reduce stress responses in stroke-prone spontaneously hypertensive rats (SHRSP). 2. Under the restraint stress, SHRSP exposed to phytoncides showed lower blood pressure than those without the exposure (186.8 +/- 3.9 vs 207.7 +/- 3.4 mmHg, respectively, P < 0.01 by Student's t-test). 3. Consistent with the observation above, the plasma concentration of catecholamines under the restraint stress was lower in the phytoncides group than in the control group. 4. Based on these results, we concluded that phytoncides reduced the cardiovascular response to restraint stress in SHRSP.
Kawakami
Kohei
K
Department of Experimental Animals, Centre for Integrated Research in Science, Shimane University, Izumo, Japan. kkawaka@med.shimane-u.ac.jp
Kawamoto
Mai
M
Nomura
Masato
M
Otani
Hiroki
H
Nabika
Toru
T
Gonda
Tatsuo
T
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D008297:Male; D009638:Norepinephrine / Q000097:blood; D009812:Odorants; D051381:Rats; D011918:Rats, Inbred SHR; D012149:Restraint, Physical; D013312:Stress, Physiological / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D013729:Terpenes / Q000627:therapeutic use*
D013729:Terpenes; D009638:Norepinephrine