title: Randomized controlled trial of nocturnal splinting for active workers with symptoms of carpal tunnel syndrome.
abstract: OBJECTIVE
  To determine whether nocturnal splinting of workers identified through active surveillance with symptoms consistent with carpal tunnel syndrome (CTS) would improve symptoms and median nerve function as well as impact medical care.
  
  
  METHODS
  Randomized controlled trial.
  
  
  METHODS
  A Midwestern auto assembly plant.
  
  
  METHODS
  Active workers with symptoms suggestive of CTS based on a hand diagram.
  
  
  METHODS
  The treatment group received customized wrist splints, which were worn at night for 6 weeks; the control group received ergonomic education alone.
  
  
  METHODS
  Change in wrist, hand, and/or finger discomfort, carpal tunnel symptom severity index, median sensory nerve function, and the percentage of subjects who had carpal tunnel release surgery.
  
  
  RESULTS
  The splinted group, unlike the controls, had a significant reduction in wrist, hand, and/or finger discomfort and a similar trend in the Levine carpal tunnel symptom severity index, which was maintained at 12 months. A secondary analysis showed that more median nerve impairment at baseline was associated with less clinical improvement among controls but not among the splinted group.
  
  
  CONCLUSIONS
  Workers identified with CTS symptoms in an active symptom surveillance tended to benefit from a 6-week nocturnal splinting trial, and the benefits were still evident at the 1-year follow-up. The splinted group improved in terms of hand discomfort regardless of the degree of median nerve impairment, whereas the controls showed improvement only among subjects with normal median nerve function. Results suggest that a short course of nocturnal splinting may reduce wrist, hand, and/or finger discomfort among active workers with symptoms consistent with CTS.
authors.affiliation: Department of Physical Medicine and Rehabilitation, University of Michigan Health System, Ann Arbor, MI 48105, USA. rawerner@umich.edu
authors.forename: Robert A
authors.initials: RA
authors.lastname: Werner
authors.forename: Alfred
authors.initials: A
authors.lastname: Franzblau
authors.forename: Nancy
authors.initials: N
authors.lastname: Gell
mesh_terms: D000328:Adult; D002349:Carpal Tunnel Syndrome / Q000150:complications / Q000628:therapy*; D019454:Chronotherapy; D005260:Female; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000503:physiopathology; D008875:Middle Aged; D009431:Neural Conduction / Q000502:physiology; D009784:Occupational Diseases / Q000150:complications / Q000628:therapy*; D010146:Pain / Q000209:etiology / Q000517:prevention & control; D010147:Pain Measurement; D020127:Recovery of Function / Q000502:physiology; D012720:Severity of Illness Index; D013165:Splints; D016896:Treatment Outcome