title: The incidence of optic neuritis in Split-Dalmatia county, Croatia.
abstract: The aim of the study was to determine the incidence of monosymptomatic optic neuritis (MON) in residents of Split-Dalmatia County, Croatia. The 127 cases (83 female, aged 26.2+/-9.9 and 44 male aged 26.9+/-11.2) with MON presented between January 1985 and December 2001 were analyzed from hospital data. The annual incidence was 1.6 per 100,000 (95% CI, 0-3). The incidence among females was 2.2 (95% CI, 0-4.6) cases / 100,000 per year and 1.1 (95% CI, 0-3) among males. The difference in incidence rates for women vs. men was not significant (chi2=0.41; p=0.52), although it is more likely that a true difference exists. The peak incidence in both sexes observed in the group 20-29 years of age was 4.2 (95% CI, 0-10). The highest incidence of MON was found in spring (46 cases). In summary, the incidence of MON in Split-Dalmatia County during the 17 years period is relatively low.
authors.affiliation: Department of Ophthalmology, University Hospital Split, Split, Croatia.
authors.forename: Lovro
authors.initials: L
authors.lastname: Bojić
authors.forename: Milan
authors.initials: M
authors.lastname: Ivanisević
authors.forename: Alen
authors.initials: A
authors.lastname: Sinićić
authors.forename: Mladen
authors.initials: M
authors.lastname: Lesin
authors.forename: Veljko
authors.initials: V
authors.lastname: Rogosić
authors.forename: Zdravko
authors.initials: Z
authors.lastname: Mandić
authors.forename: Branimir
authors.initials: B
authors.lastname: Cerovski
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D017523:Croatia / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009902:Optic Neuritis / Q000453:epidemiology*; D012189:Retrospective Studies; D012306:Risk; D017678:Sex Distribution