The teichoic acid (C-polysaccharide) synthesized by Streptococcus pneumoniae serotype 5 has a specific structure.
The teichoic acid synthesized by Streptococcus pneumoniae serotype 5, also known as pneumococcal common antigen (C-polysaccharide), was purified. On the basis of compositional analysis, HPAEC-PAD analysis, MALDI-TOF mass spectrometry and NMR spectroscopy, made on the native polysaccharide and on the dephosphorylated repeating unit, the following structure is proposed: [structure: see text]. This C-polysaccharide (C-PS), differs from those previously described by the replacement of Glc by Gal in its repeating unit structure.
Vialle
Sandrine
S
Aventis Pasteur, Campus Mérieux, Biochemistry Research Department, 1541 Avenue Marcel Mérieux, F-69280 Marcy l' Etoile, France.
Sepulcri
Patricia
P
Dubayle
Jean
J
Talaga
Philippe
P
D002240:Carbohydrate Sequence; D006858:Hydrofluoric Acid / Q000494:pharmacology; D006868:Hydrolysis / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D012703:Serotyping; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013296:Streptococcus pneumoniae / Q000737:chemistry / Q000145:classification* / Q000378:metabolism*; D013682:Teichoic Acids / Q000737:chemistry* / Q000302:isolation & purification
D013682:Teichoic Acids; D006858:Hydrofluoric Acid