Ocular manifestations in Dengue fever.
OBJECTIVE
To report a case of Dengue fever resulting in permanent visual loss in both eyes due to retinal capillary occlusion.


METHODS
Case report.


RESULTS
Severe permanent visual loss occurred in a patient with Dengue fever. Dilated fundus exam showed vascular sheathing with associated retinal hemorrhages at the equator and cotton wool spots in the maculae of both eyes. Fluorescein angiography revealed areas of capillary nonperfusion at the equator and in the macula. The diagnosis of Dengue fever was confirmed by serology detecting IgM antibodies to the Dengue virus.


CONCLUSIONS
Ocular abnormalities may be seen in patients with Dengue fever, therefore ophthalmoscopy should be performed in patients presenting with severe forms of the disease.
Siqueira
Rubens Camargo
RC
CERV, Retina, Belo Horizonte, MG, Brazil. rubenssiqueira@terra.com.br
Vitral
Newton Pena
NP
Campos
Wesley Ribeiro
WR
Oréfice
Fernando
F
de Moraes Figueiredo
Luis Tadeu
LT
D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D001241:Aspirin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003715:Dengue / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D003716:Dengue Virus / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D015828:Eye Infections, Viral / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D017075:Laser Coagulation; D008279:Magnetic Resonance Imaging; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D012166:Retinal Hemorrhage / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D031300:Retinal Vasculitis / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D014786:Vision Disorders / Q000175:diagnosis / Q000628:therapy / Q000821:virology; D014821:Vitrectomy
D000914:Antibodies, Viral; D007075:Immunoglobulin M; D010975:Platelet Aggregation Inhibitors; D001241:Aspirin