Multiple components of epiretinal tissues detected by triamcinolone and indocyanine green in macular hole and retinal detachment as a result of high myopia.
OBJECTIVE
To examine three layers of membranes detected by triamcinolone acetonide (TA) and indocyanine green (ICG) during surgery for macular hole and retinal detachment (MHRD) as a result of high myopia.


METHODS
Histologic study.


METHODS
We excised three layers of membranes visualized with TA and ICG that were tightly adhering to the retinal surface during vitrectomy and examined them by transmission electron microscopy.


RESULTS
The first membrane was made of acellular collagen fibers, suggestive of vitreous, and the second was comprised of parts of fibroblast-like cells and collagen fibrils, suggesting a proliferative epiretinal membrane. The third membrane was an internal limiting membrane.


CONCLUSIONS
Multiple components of epiretinal tissue could be delaminated with the assistance of TA and ICG during surgery for myopic MHRD.
Sakaguchi
Hirokazu
H
Osaka University Medical School, Department of Ophthalmology, Osaka, Japan. sakaguh@ophthal.med.osaka-u.ac.jp
Ikuno
Yasushi
Y
Choi
Jun-Sub
JS
Ohji
Masahito
M
Tano
Tasuo
T
D000368:Aged; D004396:Coloring Agents; D019773:Epiretinal Membrane / Q000473:pathology* / Q000601:surgery; D005260:Female; D005938:Glucocorticoids; D006801:Humans; D007208:Indocyanine Green; D046529:Microscopy, Electron, Transmission; D009216:Myopia / Q000150:complications*; D012163:Retinal Detachment / Q000209:etiology / Q000601:surgery*; D012167:Retinal Perforations / Q000209:etiology / Q000601:surgery*; D014222:Triamcinolone Acetonide; D014821:Vitrectomy
D004396:Coloring Agents; D005938:Glucocorticoids; D014222:Triamcinolone Acetonide; D007208:Indocyanine Green