Pentalogy of Cantrell: a case report with pathologic findings.
We present the case of a 28-h-old female infant born at 37 weeks of gestation with a rare congenital malformation consisting of a pentad of findings: ectopia cordis, a midline supraumbilical wall defect, a defect of the lower sternum, absent pericardium, and an anterior diaphragmatic defect. This constellation of defects is known as the pentalogy of Cantrell. Additional autopsy findings included a bilateral cleft lip and palate, bilateral pulmonary hypoplasia, an atrial septal defect, and a patent ductus arteriosus. We present this case because of its rarity and discuss the pathologic findings.
Correa-Rivas
María S
MS
Department of Pathology and Laboratory Medicine, University of Puerto Rico, Medical Sciences Campus, San Juan, PR 00936-5067, USA. mariascorrea@hotmail.com
Matos-Llovet
Isabel
I
García-Fragoso
Lourdes
L
D034861:Abdominal Wall / Q000002:abnormalities*; D000015:Abnormalities, Multiple / Q000473:pathology*; D003964:Diaphragm / Q000002:abnormalities*; D005260:Female; D006330:Heart Defects, Congenital / Q000209:etiology*; D006801:Humans; D007231:Infant, Newborn; D013249:Sternum / Q000002:abnormalities*