Flow injection spectrophotometric determination of Al in hemodialysis solutions.
A flow analysis (FA) system with spectrophotometric detection for Al determination in hemodialysis solutions was developed. The method was based on the reaction of Al with eriochrome cyanine R (ECR). The complex formed associated with cetyltrimethylammonium bromide (CTAB)--a cationic surfactant, which showed enough sensitivity to execute the direct analyte determination. All interferences were eliminated with the matrix matching calibration. The system presented the following analytic parameters: sensitivity (m) of 8.10 x 10(-4)L microg(-1), limit of detection (LOD) of 3.24 microg L(-1) (3sigma), linear correlation coefficient of 0.9966 and linear range response from 10.8 to 650 microg L(-1). The accuracy of the proposed method was checked by comparison with electrothermal atomic absorption spectrometry (ET-AAS) method. There were no differences among the results obtained from both methods, at a confidence level of 95% (paired t-test). Recovery tests were also made, values obtained were from 90.4 to 109 of recovery for Al-spiked samples.
Rodrigues
Jairo Lisboa
JL
Departamento de Ciências Exatas, Escola de Farmácia e Odontologia de Alfenas-Centro Universitário Federal, Cep 37130-000 Alfenas, MG, Brazil.
de Magalhães
Cristiana Schmidt
CS
Luccas
Pedro Orival
PO
D000535:Aluminum / Q000032:analysis*; D004340:Drug Contamination; D017022:Flow Injection Analysis / Q000379:methods; D015312:Hemodialysis Solutions / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet / Q000379:methods
D015312:Hemodialysis Solutions; D000535:Aluminum