title: Rapid progression of destructive spondyloarthropathy.
abstract: METHODS
  A case of destructive spondyloarthropathy was reported.
  
  
  OBJECTIVE
  To describe the rapid destruction of intervertebral disc and vertebral body as a consequence of destructive spondyloarthropathy in a patients with end-stage renal disease receiving hemodialysis.
  
  
  BACKGROUND
  An important facet of this case is that the serial radiographs provide key information about the rapid nature of dialysis associated destructive spondyloarthropathy, a condition which has been increasingly recognized over the last 2 decades.
  
  
  METHODS
  The clinical and radiologic features of a 55-year-old dialysis patient with destructive spondyloarthropathy are herein detailed. Her serial radiographs and magnetic resonance images have implications both for our understanding of the underlying destructive process and its clinical evaluation.
  
  
  RESULTS
  Serial lateral lumbar spines illustrated that the destructive process started at the leading edge of the endplate of vertebral body, closely followed by adjacent intervertebral disc destruction that appeared in parallel with vertebral body bone resorption.
  
  
  CONCLUSIONS
  A case of dialysis-associated destructive spondyloarthropathy was reported, with key information about its rapid nature being provided by serial radiographs.
authors.affiliation: Department of Medicine & Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, China.
authors.forename: Kai Ming
authors.initials: KM
authors.lastname: Chow
authors.forename: James Francis
authors.initials: JF
authors.lastname: Griffith
authors.forename: Kwai Yau
authors.initials: KY
authors.lastname: Fung
authors.forename: Cheuk Chun
authors.initials: CC
authors.lastname: Szeto
mesh_terms: D000686:Amyloidosis / Q000209:etiology / Q000378:metabolism; D018450:Disease Progression; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000628:therapy*; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging; D008875:Middle Aged; D011859:Radiography; D006435:Renal Dialysis / Q000009:adverse effects*; D025242:Spondylarthropathies / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D001613:beta 2-Microglobulin / Q000378:metabolism
chemical_list: D001613:beta 2-Microglobulin