title: Surgical treatment of infective endocarditis.
abstract: OBJECTIVE
  The objective of this study is to determine the surgical indication in the treatment of infective endocarditis.
  
  
  METHODS
  Retrospective study in a tertiary care--Wessex Cardiothoracic--Centre.
  
  
  METHODS
  Case records of patients admitted with infective endocarditis for surgical treatment between 1984 to 1994 at Wessex Cardiothoracic Centre were analysed. This analysis includes the age, sex, microbiology results, risk factors, surgical indication and early results.
  
  
  RESULTS
  A total of 123 patients was admitted with bacterial endocarditis treated surgically since 1984. The mean age was 51.9 years with male:female ratio of 3:1. The most common causative organism was streptococcus (63%) and staphylococcus (30%). Native valve endocarditis occurred in 111 patients, affecting the aortic, mitral, combined aortic and mitral valve in 69%, 33%, and 8% of cases, respectively. Late prosthetic valve endocarditis occurred in 12 patients. The most common indication for surgery was heart failure (84%), uncontrolled sepsis (8%), and recurrent endocarditis (2.5%). Hospital mortality was 1.6%. Complete heart block and cerebrovascular accident developed in 4% and 2.4%, respectively.
  
  
  CONCLUSIONS
  Heart failure is the main indication for surgery. Valve replacement with mechanical prosthesis is a safe procedure with a low rate of mortality and complication.
authors.affiliation: Wessex Cardiothoracic Centre, Southampton University Hospital, Southampton, United Kingdom. akramasaleh@yahoo.com
authors.forename: Akram
authors.initials: A
authors.lastname: Saleh
authors.forename: Keith
authors.initials: K
authors.lastname: Dawkins
authors.forename: John
authors.initials: J
authors.lastname: Monro
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D004697:Endocarditis, Bacterial / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014463:Ultrasonography