title: Predictors of quality of life in women with a bilateral prophylactic mastectomy.
abstract: The purpose of this study was to assess the quality of life in women who had previously undergone a bilateral prophylactic mastectomy and to determine what factors predict quality of life in this population. Women in Ontario who had undergone prophylactic mastectomy between 1991 and 2000 were asked to complete several questionnaires that assessed current psychosocial functioning, including the Quality of Life Index (QLI). The mean score for the QLI was 23.34 (range 9.53-30.00). QLI scores were negatively correlated with cancer-related distress, body image difficulties, and psychological distress. Conversely, QLI scores were positively correlated with social support. Significant predictors of quality of life included psychological distress and one subscale of body image (vulnerability). Vulnerability and psychological distress are important predictors of quality of life in women who have previously undergone bilateral prophylactic mastectomy.
authors.affiliation: The Center for Research in Women's Health, Sunnybrook and Women's College Health Sciences Center, University of Toronto, Toronto, Ontario, Canada. kelly.metcalfe@utoronto.ca
authors.forename: Kelly A
authors.initials: KA
authors.lastname: Metcalfe
authors.forename: Mary Jane
authors.initials: MJ
authors.lastname: Esplen
authors.forename: Vivek
authors.initials: V
authors.lastname: Goel
authors.forename: Steven A
authors.initials: SA
authors.lastname: Narod
mesh_terms: D000328:Adult; D001828:Body Image; D001943:Breast Neoplasms / Q000517:prevention & control / Q000523:psychology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008408:Mastectomy / Q000523:psychology / Q000706:statistics & numerical data*; D008499:Medical Records; D008875:Middle Aged; D009864:Ontario / Q000453:epidemiology; D011788:Quality of Life / Q000523:psychology*; D012189:Retrospective Studies; D012944:Social Support; D013315:Stress, Psychological; D011795:Surveys and Questionnaires