title: Karyotypic conservatism in the suborder Feliformia (Order Carnivora).
abstract: Multidirectional comparative chromosome painting was used to investigate the karyotypic relationships among representative species from three Feliformia families of the order Carnivora (Viverridae, Hyaenidae and Felidae). Complete sets of painting probes derived from flow-sorted chromosomes of the domestic dog, American mink, and human were hybridized onto metaphases of the spotted hyena (Crocuta crocuta, 2n = 40) and masked palm civet (Paguma larvata, 2n = 44). Extensive chromosomal conservation is evident in these two species when compared with the cat karyotype, and only a few events of chromosome fusion, fission and inversion differentiate the karyotypes of these Feliformia species. The comparative chromosome painting data have enabled the integration of the hyena and palm civet chromosomes into the previously established comparative map among the domestic cat, domestic dog, American mink and human and improved our understanding on the karyotype phylogeny of Feliformia species.
authors.affiliation: Institute of Cytology and Genetics, Novosibirsk, Russia.
authors.forename: P L
authors.initials: PL
authors.lastname: Perelman
authors.forename: A S
authors.initials: AS
authors.lastname: Graphodatsky
authors.forename: N A
authors.initials: NA
authors.lastname: Serdukova
authors.forename: W
authors.initials: W
authors.lastname: Nie
authors.forename: E Z
authors.initials: EZ
authors.lastname: Alkalaeva
authors.forename: B
authors.initials: B
authors.lastname: Fu
authors.forename: T J
authors.initials: TJ
authors.lastname: Robinson
authors.forename: F
authors.initials: F
authors.lastname: Yang
mesh_terms: D000818:Animals; D002335:Carnivora / Q000235:genetics*; D002415:Cats; D002871:Chromosome Banding / Q000379:methods; D020223:Chromosome Painting / Q000379:methods; D002877:Chromosomes, Human / Q000235:genetics; D033481:Chromosomes, Mammalian / Q000235:genetics; D017124:Conserved Sequence / Q000235:genetics*; D015342:DNA Probes / Q000235:genetics; D004285:Dogs; D006801:Humans; D045968:Hyaenidae / Q000235:genetics; D007621:Karyotyping / Q000379:methods*; D008907:Mink / Q000235:genetics; D045949:Viverridae / Q000235:genetics
chemical_list: D015342:DNA Probes