title: Macular hole in Behcet's disease.
abstract: Behcet's disease is an inflammatory disorder of unknown cause, characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. Ocular involvement occurs in 60-80% of patients with Behcet's disease and presents as panuveitis in most cases. Posterior segment involvement may lead to irreversible alterations and significant vision loss. The development of a partial or full-thickness macular hole, though rarely reported, may cause serious vision loss. In this report, we present two cases of macular hole in the worse eye of bilateral cases of Behcet's disease, and discuss the possible mechanisms and management in such cases.
authors.affiliation: Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan. sjsheu@isca.vghks.gov.tw
authors.forename: Shwu-Jiuan
authors.initials: SJ
authors.lastname: Sheu
authors.forename: Cheng-An
authors.initials: CA
authors.lastname: Yang
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001528:Behcet Syndrome / Q000150:complications*; D016572:Cyclosporine / Q000627:therapeutic use; D005123:Eye / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D010146:Pain / Q000209:etiology; D010211:Papilledema / Q000209:etiology / Q000628:therapy; D012166:Retinal Hemorrhage / Q000209:etiology / Q000628:therapy; D012167:Retinal Perforations / Q000209:etiology*; D016896:Treatment Outcome; D014786:Vision Disorders / Q000209:etiology / Q000628:therapy
chemical_list: D000305:Adrenal Cortex Hormones; D016572:Cyclosporine