title: [Bronchial asthma and menopause].
abstract: The existing literature suggests that asthmatic women suffer from an increase in asthma symptoms just before and during menstruation. Many investigators speculated that estrogen and progesterone plays a modulating role in asthma features. Estradiol administration was associated with improvement in symptoms, dyspnea index scores, pulmonary function, and decrease in corticosteroid requirement. It is established that estrogen deficiency plays an important role in the pathogenesis of post-menopausal osteoporosis particularly in women with steroid-dependent asthma. This article provides an overview of the mechanisms of beneficial effects of in estrogen and progesterone therapy in asthmatic post- menopausal women.
authors.affiliation: Katedra i Klinika Alergologii i Chorób Wewnetrznych AM w Bydgoszczy.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Dziedziczko
authors.forename: Anna
authors.initials: A
authors.lastname: Wojtaszek
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Pałgan
mesh_terms: D001249:Asthma / Q000453:epidemiology / Q000378:metabolism / Q000503:physiopathology*; D004967:Estrogens / Q000378:metabolism; D005260:Female; D006801:Humans; D008593:Menopause / Q000378:metabolism*; D008875:Middle Aged; D010024:Osteoporosis / Q000453:epidemiology / Q000378:metabolism; D011374:Progesterone / Q000378:metabolism
chemical_list: D004967:Estrogens; D011374:Progesterone