title: New drugs and new targets.
abstract: At the 8th World Congress on Clinical Pharmacology and Therapeutics, held August 1-6, 2004, in Queensland, Australia, there were late-breaking news symposia on presynaptic receptors as targets in the treatment of schizophrenia; cyclooxygenase inhibition, present and future; adiposity, drug treatment and causes; G-protein-coupled receptors, important new targets; osteoporosis, causes, prevention and cures; ischemic stroke; drugs and arrhythmias, causes and cures; and the pharmacology of cardiac protection. One of the plenary lectures was of targeted cancer therapies. The new drugs and new targets for therapeutic intervention from these presentations are discussed in this report.
authors.affiliation: University of Queensland, School of Biomedical Sciences, QLD 4072, Australia. s_doggrell@yahoo.com
authors.forename: Sheila A
authors.initials: SA
authors.lastname: Doggrell
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000600:supply & distribution / Q000627:therapeutic use; D001296:Audiovisual Aids; D001315:Australia; D016861:Cyclooxygenase Inhibitors / Q000737:chemistry / Q000627:therapeutic use; D016503:Drug Delivery Systems / Q000379:methods* / Q000639:trends; D015195:Drug Design; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D008133:Long QT Syndrome / Q000139:chemically induced / Q000188:drug therapy; D017202:Myocardial Ischemia / Q000188:drug therapy / Q000503:physiopathology; D019255:NADPH Oxidases / Q000037:antagonists & inhibitors / Q000627:therapeutic use; D009765:Obesity / Q000188:drug therapy / Q000209:etiology; D010024:Osteoporosis / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D010595:Pharmacists / Q000458:organization & administration / Q000639:trends; D010597:Pharmacogenetics / Q000639:trends; D010601:Pharmacology, Clinical / Q000458:organization & administration / Q000639:trends; D043562:Receptors, G-Protein-Coupled / Q000187:drug effects / Q000627:therapeutic use; D017661:Receptors, Presynaptic / Q000187:drug effects / Q000627:therapeutic use; D012559:Schizophrenia / Q000188:drug therapy; D012958:Societies, Scientific / Q000458:organization & administration; D020521:Stroke / Q000188:drug therapy / Q000453:epidemiology
chemical_list: D000970:Antineoplastic Agents; D016861:Cyclooxygenase Inhibitors; D043562:Receptors, G-Protein-Coupled; D017661:Receptors, Presynaptic; D019255:NADPH Oxidases