Updated classification of hemangiomas and other vascular anomalies.
Vascular anomalies comprise a widely heterogenous group of tumors and malformations. Great confusion has arisen because of the term hemangioma has been and is continued to be used to represent a multitude of vascular entities. This review presents the updated classification of vascular anomalies with the goal of clarifying the term hemangioma. In addition, newer clinical concepts in hemangiomas and other vascular tumors is presented. Hemangioma subtypes and hemangioma variants are also discussed, and a brief review of pyogenic granuloma and Kaposiform hemangioendothelioma is provided. Finally, the immunohistochemical marker GLUT1 is reviewed, a marker that heralds a new era in vascular anomalies research.
Chang
Mary Wu
MW
Department of Dermatology, New York University School of Medicine, New York, New York 10016, USA. Changm02@med.nyu.edu
D018376:Cardiovascular Abnormalities / Q000145:classification / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004730:Endothelium, Vascular / Q000473:pathology*; D005260:Female; D051272:Glucose Transporter Type 1; D017789:Granuloma, Pyogenic / Q000175:diagnosis; D006390:Hemangioendothelioma / Q000175:diagnosis; D006391:Hemangioma / Q000145:classification / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009004:Monosaccharide Transport Proteins / Q000096:biosynthesis; D019043:Vascular Neoplasms / Q000145:classification / Q000175:diagnosis
D051272:Glucose Transporter Type 1; D009004:Monosaccharide Transport Proteins; C495677:SLC2A1 protein, human