title: Triterpenes from Maesopsis eminii.
abstract: Two pentacyclic triterpenes, 1alpha,3beta-dihydroxybauer-7-en-28-oic acid (1) and 3beta-hydroxybauer-7-en-28-oic acid (2), together with sitosterol-3-beta-O-d-glucopyranoside and stigmasterol have been isolated from the bark of the plant Maesopsis eminii. Their structures have been elucidated by spectroscopic methods. One of the triterpenes (1) is new, and its structure was confirmed by X-ray crystallographic analysis. This new triterpene displayed moderate antibacterial activity against Bacillus subtilis ATCC 6633.
authors.affiliation: Department of Chemistry, University of Bielefeld, PO Box 100131, 33501 Bielefeld, Germany.
authors.forename: Patrice Aimé
authors.initials: PA
authors.lastname: Fokou
authors.forename: Hans-Georg
authors.initials: HG
authors.lastname: Stammler
authors.forename: Beate
authors.initials: B
authors.lastname: Neumann
authors.forename: Thomas
authors.initials: T
authors.lastname: Huber
authors.forename: David
authors.initials: D
authors.lastname: Lontsi
authors.forename: Hilaire V Kemami
authors.initials: HV
authors.lastname: Wangun
authors.forename: Norbert
authors.initials: N
authors.lastname: Sewald
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D002163:Cameroon; D018360:Crystallography, X-Ray; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D024301:Plant Bark / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D027823:Rhamnaceae / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: C497306:1alpha,3beta-dihydroxybauer-7-en-28-oic acid; C497307:3beta-hydroxybauer-7-en-28-oic acid; D000900:Anti-Bacterial Agents; D014315:Triterpenes