Genome stability: a self-sufficient DNA repair machine.
The repair of DNA double-strand breaks often requires the broken ends to be processed prior to religation. New results describe a bacterial enzyme with processing and rejoining activities encoded in a single polypeptide chain.
MacNeill
Stuart A
SA
Wellcome Trust Centre for Cell Biology, University of Edinburgh, Michael Swann Building, King's Buildings, Mayfield Road, Edinburgh EH9 3JR, Scotland, UK. s.a.macneill@ed.ac.uk
D001419:Bacteria / Q000235:genetics*; D004265:DNA Helicases / Q000235:genetics*; D004260:DNA Repair; D042822:Genomic Instability / Q000235:genetics*; D008957:Models, Genetic; D017434:Protein Structure, Tertiary
D004265:DNA Helicases