[The role of viral infection in emergence and progression of primary glomerulonephritis and some nephropathies].
The results of this study confirm the importance of virus infection in nephropathy onset and progression. Virus-like inclusions were found at electron microscopy in 70 (46 children and 24 adults) of 136 total diagnostic biopsies. In another group of patients (68 adults--50 males and 18 females) with virus-like inclusions in the kidney biopsy studied electron microscopically detected 12 types of viruses observed by PCR in the tissue, present either separately or in various combinations, 2 or 3 simultaneously. The most widespread were Herpes simplex virus, adenovirus and hantovirus. Interrelationship between morphological forms of nephropathies and observed viruses is analyzed. Parvovirus B19 was observed only in FSGS/G and arteryohyalinosis.
Varshavskiĭ
V A
VA
Golitsina
E P
EP
Rybin
P N
PN
Fedorov
D N
DN
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology / Q000473:pathology* / Q000821:virology; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology / Q000473:pathology* / Q000821:virology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D014777:Virus Diseases / Q000150:complications / Q000473:pathology*