High doses of acyclovir: a new concept in the treatment of neonatal herpes simplex virus infection.
The authors present a case of a preterm newborn with congenital infection of herpes simplex virus type 2. The patient was treated with newly recommended high intravenous doses of acyclovir. It can be supposed that it reduces mortality, but the high morbidity continues to be a problem.
Melichar
Jan
J
Neonatal Intensive Care Unit, Institute for the Care of Mother and Child, and 3rd School of Medicine, Charles University, Prague, Czech Republic
Miletin
Jan
J
Janota
Jan
J
Kucera
Jáchym
J
Cunat
Václav
V
Sanáková
Petra
P
Stranák
Zbynek
Z
D000212:Acyclovir / Q000008:administration & dosage*; D018792:Encephalitis, Viral / Q000188:drug therapy*; D006561:Herpes Simplex / Q000188:drug therapy*; D018258:Herpesvirus 2, Human; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000188:drug therapy*
D000212:Acyclovir