title: [Signet ring cell lymphoma mimicking mucin-producing carcinoma].
abstract: Signet ring cell lymphoma is a rare neoplasm characterized by large, vacuolated and clear cells mimicking mucin-producing adenocarcinoma. It is localized in nodal and extranodal sites. A case of a 59 years old male, with a diffuse lymphoma signet ring cell type localized on oropharyngeal mucosa is reported. The histopathology study showed signet ring cells and the immunophenotype was: vimentine(+), CD45(+), CD20(+), Ig M(+), Kappa chain(+) and high index proliferative activity of neoplastic cells (Ki 67:70%). After a review of the literature and previous reports, we could not find a similar case in this anatomic site. The patient had a unfavourable clinical course and died two months after the diagnosis without receiving any treatment.
authors.affiliation: Departamento de Patología, Instituto de Oncología Angel H. Roffo, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
authors.forename: Ana María
authors.initials: AM
authors.lastname: Sáenz de Chirife
authors.forename: Erica
authors.initials: E
authors.lastname: Rojas Bilbao
authors.forename: Liliana
authors.initials: L
authors.lastname: Giménez
authors.forename: Lina
authors.initials: L
authors.lastname: Marino
authors.forename: Francisco
authors.initials: F
authors.lastname: Celeste
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000473:pathology*; D018279:Carcinoma, Signet Ring Cell / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D016393:Lymphoma, B-Cell / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009959:Oropharyngeal Neoplasms / Q000473:pathology*; D016896:Treatment Outcome