Treatment of low-grade oligodendroglial tumors without radiotherapy.
The authors prospectively treated 18 consecutive patients with low-grade oligodendroglial tumors without postoperative radiotherapy. The treatment strategy was as follows: follow-up after total resection and chemotherapy after subtotal resection or biopsy. All patients were alive and 17 patients (94%) were progression-free after a median follow-up of 4.7 years. The results suggested that radiotherapy could be postponed until clinical progression in the treatment of low-grade oligodendroglial tumors.
Higuchi
Yoshinori
Y
Department of Neurological Surgery, Chiba University Graduate School of Medicine, Chiba City, Japan.
Iwadate
Yasuo
Y
Yamaura
Akira
A
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001706:Biopsy; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology / Q000601:surgery; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015993:Life Tables; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D015376:Nimustine / Q000008:administration & dosage; D009837:Oligodendroglioma / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology / Q000601:surgery; D011344:Procarbazine / Q000008:administration & dosage; D011446:Prospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome; D014750:Vincristine / Q000008:administration & dosage
D015376:Nimustine; D011344:Procarbazine; D014750:Vincristine