title: Stent-assisted coil placement for unruptured cerebral aneurysms.
abstract: OBJECTIVE
  The treatment of wide-necked cerebral aneurysms represents a challenging problem for neurosurgeons. The recent development of stents has provided clinicians with the ability to treat these aneurysms while keeping the parent vessel patent. The long-term occlusion rate of aneurysms treated with stent-assisted coil placement has yet to be investigated. The authors report the use of a new intracranial stent-the Neuroform microstent-in the treatment of unruptured wide-necked cerebral aneurysms.
  
  
  METHODS
  Thirty-two patients harboring unruptured wide-necked intracranial aneurysms underwent a stent-assisted coil placement procedure. Patients were pretreated with antiplatelet agents, and a stent was positioned across the neck of the aneurysm. The next step was the insertion of coils into the aneurysm cavity. Patients received anticoagulation therapy for 24 hours after the procedure. All 32 patients with unruptured wide-necked cerebral aneurysms were suitable candidates for this procedure. Occlusion of at least 90% of the aneurysm was achieved in 24 patients (75%) and 0% occlusion was observed in five patients (15%). Two patients experienced thromboembolic events, one of which was directly related to the stent. The overall complication rate was 6.3%.
  
  
  CONCLUSIONS
  Intracranial stents will be used more frequently in the new era of endovascular management of widenecked cerebral aneurysms. With some technical improvements and more data on long-term occlusion rates, this new modality should improve the occlusion of wide-necked cerebral aneurysms while protecting the parent vessel.
authors.affiliation: Department of Neurosurgery, Thomas Jefferson University School of Medicine, Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania, USA. Pascal.jabbour@mail.tju.edu
authors.forename: Pascal
authors.initials: P
authors.lastname: Jabbour
authors.forename: Christopher
authors.initials: C
authors.lastname: Koebbe
authors.forename: Erol
authors.initials: E
authors.lastname: Veznedaroglu
authors.forename: Ronald P
authors.initials: RP
authors.lastname: Benitez
authors.forename: Robert
authors.initials: R
authors.lastname: Rosenwasser
mesh_terms: D000328:Adult; D000368:Aged; D017542:Aneurysm, Ruptured; D000925:Anticoagulants / Q000627:therapeutic use; D002548:Cerebral Revascularization / Q000295:instrumentation* / Q000379:methods* / Q000706:statistics & numerical data; D006801:Humans; D002532:Intracranial Aneurysm / Q000188:drug therapy / Q000601:surgery*; D008875:Middle Aged; D015607:Stents / Q000706:statistics & numerical data
chemical_list: D000925:Anticoagulants