title: [Present and future prospects of external radiation cancer treatment].
abstract: Radiotherapy is the most applicable method in the treatment of cancer patients. Rapid advances in radiotherapy and imaging techniques allow improvement in definition of target margins, volumes, and organs at risk. Conformal radiotherapy using multileaf collimator was introduced towards the end of the 1980s. Further improvements in dose distribution were possible through intensity modulation radiation therapy based on the use of computer-controlled multileaf collimators for creating the desired dose variation inside a radiation field. The dose of definite radiotherapy is limited by dose tolerance of organs or tissues at risk near the target. In the last 50 years radiotherapy modalities achieved rapid developments, particularly in field of treatment planning and dose distribution. The main goal of that development is to apply definite radiotherapy dose to target and minimize normal tissue irradiation, leaving the patient free of treatment related morbidity.
authors.affiliation: Institute of Oncology, Vilnius University, Santariskiu 1, 08660 Vilnius, Lithuania.
authors.forename: Konstantinas Povilas
authors.initials: KP
authors.lastname: Valuckas
authors.forename: Eduardas
authors.initials: E
authors.lastname: Aleknavicius
authors.forename: Mindaugas
authors.initials: M
authors.lastname: Grybauskas
mesh_terms: D003131:Combined Modality Therapy; D019583:Dose Fractionation, Radiation; D005544:Forecasting; D006801:Humans; D008279:Magnetic Resonance Imaging; D009369:Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery; D017785:Photons / Q000627:therapeutic use; D011839:Radiation, Ionizing; D011877:Radionuclide Imaging; D011878:Radiotherapy / Q000009:adverse effects; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D020266:Radiotherapy, Conformal; D050397:Radiotherapy, Intensity-Modulated; D013997:Time Factors; D014057:Tomography, X-Ray Computed