Neurotoxicity of cancer chemotherapy.
Neurological dysfunction is a common side effect of many chemotherapy drugs. For several agents neurotoxicity is common, severe, and can be dose-limiting. This is a review of the clinical features of chemotherapy-induced syndromes involving the central and peripheral nervous systems.
Dropcho
Edward J
EJ
Department of Neurology, Indiana University Medical Center, 541 Clinical Drive, CL 291, Indianapolis, IN 46202, USA.
D002561:Cerebrovascular Disorders / Q000209:etiology; D004305:Dose-Response Relationship, Drug; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy; D009422:Nervous System Diseases / Q000209:etiology; D020258:Neurotoxicity Syndromes / Q000209:etiology*; D010523:Peripheral Nervous System Diseases / Q000209:etiology