Anthraquinones from Gladiolus gandavensis.
Five new anthraquinones have been obtained from the ethanolic extracts of the subterranean corms of Gladiolus gandavensis Van Houtt. Their structures were elucidated as 3,8-dihydroxy-6-methoxy-1-methyl-anthraquinone (gandavensin D, 1), methyl 3,8-dihydroxy-6,7-methylenedioxy-1-methyl-anthraquinone- 2-carboxylate (gandavensin E, 2), 2,3,8-trihydroxy-6-methoxy-1-methoxymethyl-anthraquinone (gandavensin F, 3), 8-hydroxy-3,6-dimethoxy-1-methyl-anthraquinone-2-carboxylic acid (gandavensin G, 4) and 1,7-dihydroxy-3,6-dimethoxy-anthraquinone (gandavensin H, 5) on the basis of spectral data. The known compounds isolated for the first time from this plant have been determined to be methyl 3,6,8-trihydroxy-7-methoxy-1-methyl-anthraquinone-2-carboxylate (6), methyl 3,6,8-trihydroxy-1-methyl-anthraquinone-2-carboxylate (7), 3,8-dihydroxy-6-methoxy-1-methyl-anthraquinone-2-carboxylic acid (8), 3,6,8-trihydroxy-1-methyl-anthraquinone-2-carboxylic acid (9), 6,8-dihydroxy-3-methoxy-1-methyl-anthraquinone-2-carboxylic acid (10), methyl 3,8-dihydroxy-6-methoxy-1-methyl-anthraquinone-2-carboxylate (11) and methyl 3,7,8-trihydroxy-1-methyl-anthraquinone-2-carboxylate (12).
Chen
Bin
B
Chengdu Institute of Biology, The Chinese Academy of Sciences, Chengdu 610041, China.
Wang
Ding-Yong
DY
Ye
Qi
Q
Li
Bo-Gang
BG
Zhang
Guo-Lin
GL
D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification*; D027621:Iridaceae / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy
C497384:1,7-dihydroxy-3,6-dimethoxy-anthraquinone; C497382:2,3,8-trihydroxy-6-methoxy-1-methoxymethyl-anthraquinone; C497380:3,8-dihydroxy-6-methoxy-1-methyl-anthraquinone; C497383:8-hydroxy-3,6-dimethoxy-1-methyl-anthraquinone-2-carboxylic acid; D000880:Anthraquinones; C497381:methyl 3,8-dihydroxy-6,7-methylenedioxy-1-methyl-anthraquinone- 2-carboxylate