Right lobe living related graft loss due to intrahepatic multiple arterio-portal fistulas.
We report a case of a 38-year-old Caucasian female with ileal carcinoid and bilobar hepatic metastases. After resection of the primary tumor, octreotide therapy was prescribed. Carcinoid histology was positive for chromogranin A and sinaptophsine and negative for MIB1. At 1-year, a follow-up computed tomography scan, Octreoscan, and PET scan were negative for extrahepatic involvement. The patient underwent right lobe living related liver transplantation donated by her sister. Acute hepatic artery thrombosis was successfully revascularized 24 hours after transplantation. Extrahepatic biliary ischemia was treated by a bilio-digestive anastomosis. Eight months later, ascites and clinical and serologic signs of liver failure developed; a liver biopsy revealed fibrosis. Spiral computed tomography scan and hepatic angiography showed multiple intrahepatic arterio-portal fistulas resulting in arterialization and inversion of the portal flow in the absence of graft outflow obstruction.
Adani
G L
GL
Department of Surgery and Transplantation Unit, University Hospital, 33100 Udine, Italy.
Baccarani
U
U
Risaliti
A
A
Sainz-Barriga
M
M
Lorenzin
D
D
Bresadola
F
F
D000328:Adult; D001164:Arteriovenous Fistula / Q000473:pathology*; D002276:Carcinoid Tumor / Q000601:surgery; D005260:Female; D006499:Hepatic Artery / Q000473:pathology*; D006801:Humans; D007078:Ileal Neoplasms / Q000601:surgery; D008113:Liver Neoplasms / Q000473:pathology* / Q000556:secondary*; D016031:Liver Transplantation / Q000009:adverse effects / Q000473:pathology*; D019520:Living Donors; D011169:Portal Vein / Q000473:pathology*; D012086:Reoperation; D017211:Treatment Failure