title: Ultrasonography detection of early bone erosions in the metacarpophalangeal joints of patients with rheumatoid arthritis.
abstract: OBJECTIVE
  To compare ultrasonography (US) and magnetic resonance imaging (MRI) in their capability to detect bone erosions in early-advanced rheumatoid arthritis, where no erosion was evident on conventional radiography (X-ray).
  
  
  METHODS
  Metacarpophalangeal (MCP), radiocarpal and ulnocarpal joints of 13 patients with rheumatoid arthritis, with bone erosion that was not detected by conventional X-ray, were examined by US and MRI. Ten controls underwent examination of the same joints by US.
  
  
  RESULTS
  None of the controls showed bone erosions at US examination. No significant difference between US and MRI in detecting bone erosion was observed in wrist joints, whereas a significantly higher number of erosions was detected by US in MCP joints.
  
  
  CONCLUSIONS
  US is at least as sensitive as MRI in detecting bone erosions in MCP and wrist joints. Since US examination is a more easily available and less expensive procedure than MRI, our findings justify its use as a diagnostic tool for early arthritis. In addition US may also be utilized in the follow up of patients with an established diagnosis of inflammatory arthritis.
authors.affiliation: Ultrasonology Unit, Istituti Ortopedici Rizzoli, Bologna, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Magnani
authors.forename: E
authors.initials: E
authors.lastname: Salizzoni
authors.forename: R
authors.initials: R
authors.lastname: Mulè
authors.forename: M
authors.initials: M
authors.lastname: Fusconi
authors.forename: R
authors.initials: R
authors.lastname: Meliconi
authors.forename: S
authors.initials: S
authors.lastname: Galletti
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging* / Q000473:pathology; D002348:Carpal Bones / Q000000981:diagnostic imaging / Q000473:pathology; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008662:Metacarpophalangeal Joint / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D014955:Wrist Joint / Q000000981:diagnostic imaging / Q000473:pathology