[Advance on insulin-like growth factor 2].
Insulin-like growth factors play an important role in fetal growth and development, tumour cell proliferation and muscle growth. This review is focused on the insulin-like growth factor 2 gene structures, and their imprintings in mammalian genomes. In addition, we also discussed that IGF2 is the major paternally expressed candidate gene affecting muscle mass.
Jiang
Si-Wen
SW
College of Animal Science and Technology, Huanzhong Agricultural University, Wuhan 430 070, China. jiangsiwen@hotmail.com
Peng
Jian
J
Xiong
Yuan-Zhu
YZ
D000818:Animals; D005786:Gene Expression Regulation; D018392:Genomic Imprinting; D006801:Humans; D007335:Insulin-Like Growth Factor II / Q000235:genetics*; D040641:Quantitative Trait Loci
D007335:Insulin-Like Growth Factor II