title: [The effect of platelet-rich plasma on the distraction osteogenesis].
abstract: OBJECTIVE
  To observe the effect of the platelet-rich plasma (PRP) on osteogenesis during bone distraction.
  
  
  METHODS
  The osteoblasts were cultured in vitro. The rabbits were used as the animal model of distraction osteogenesis. The proliferation of osteoblasts was analysed through MTT methods. The osteogenesis was observed by histochemical and histoimmunochemical methods.
  
  
  RESULTS
  PRP stimulated the proliferation of osteoblasts and facilitated distraction osteogenesis.
  
  
  CONCLUSIONS
  PRP could accelerate the osteogenesis during bone distraction. The application of PRP in clinical practice might shorten the period of distraction osteogenesis.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Peking University School of Stomatology, Beijing 100081, China. lqf6668@163.com
authors.forename: Quan-feng
authors.initials: QF
authors.lastname: Luo
authors.forename: Xing
authors.initials: X
authors.lastname: Wang
authors.forename: Xiao-xia
authors.initials: XX
authors.lastname: Wang
authors.forename: Biao
authors.initials: B
authors.lastname: Yin
authors.forename: Zi-li
authors.initials: ZL
authors.lastname: Li
authors.forename: Cheng
authors.initials: C
authors.lastname: Liang
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000502:physiology*; D002478:Cells, Cultured; D007150:Immunohistochemistry; D008297:Male; D010006:Osteoblasts / Q000166:cytology / Q000378:metabolism*; D010012:Osteogenesis / Q000502:physiology; D019857:Osteogenesis, Distraction; D010976:Platelet Count; D011817:Rabbits