A biomimetic strategy for the synthesis of the tricyclic dibenzofuran-1,4-dione core of popolohuanone E.
A concise synthesis of the complete tricyclic dibenzofuran-1,4-dione aromatic core of popolohuanone E has been demonstrated by mild base treatment of a biquinone intermediate, thus establishing a biomimetic route to this family of heterocyclic ring systems and the total synthesis of popolohuanone E.
Anderson
James C
JC
School of Chemistry, University of Nottingham, Nottingham NG7 2RD, UK. j.anderson@nottingham.ac.uk
Denton
Ross M
RM
Wilson
Claire
C
D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D018716:Molecular Mimicry; D011083:Polycyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry
D001572:Benzofurans; D011083:Polycyclic Compounds; C510740:popolohuanone E; C023614:dibenzofuran