Phenotypic and molecular analysis of tellurite resistance among enterohemorrhagic Escherichia coli O157:H7 and sorbitol-fermenting O157:NM clinical isolates.
A total of 66 (98.5%) of 67 enterohemorrhagic Escherichia coli (EHEC) O157:H7 strains had increased potassium tellurite (Te) MICs (32 to 1,024 microg/ml), grew on Te-containing media, and possessed Te resistance (ter) genes, whereas 83 (96.5%) of 86 sorbitol-fermenting (SF) EHEC O157:NM strains had Te MICs of </=4 microg/ml, did not grow on Te-containing media, and lacked ter genes. Optimal detection of SF EHEC O157:NM strains requires Te-independent strategies.
Bielaszewska
Martina
M
Institut für Hygiene, Universitätsklinikum Münster, Robert Koch Str. 41, 48149 Münster, Germany. mbiela@uni-muenster.de
Tarr
Phillip I
PI
Karch
Helge
H
Zhang
Wenlan
W
Mathys
Werner
W
D003470:Culture Media; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004927:Escherichia coli Infections / Q000382:microbiology*; D019453:Escherichia coli O157 / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism; D029968:Escherichia coli Proteins / Q000235:genetics; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D010641:Phenotype; D013012:Sorbitol / Q000378:metabolism*; D013691:Tellurium / Q000494:pharmacology*
D003470:Culture Media; D029968:Escherichia coli Proteins; D013012:Sorbitol; C026899:potassium tellurate(IV); D013691:Tellurium