[Vertical transmission of hepatitis C virus].
To study the transmission of hepatitis C virus (HCV) from infected mother to their infants, out of 1047 mothers studied, 8 were anti-HCV antibody and 6 were HCV RNA positive as well as 2 mothers who were anti-HCV antibody and HCV RNA positive. 12 mothers and their 12 babies were followed up for 12 months. Only one of 12 infants showed persistently positive for anti-HCV antibody and HCV RNA at 1, 6 and 12 months of age. His HCV type was identical to his mother. These results suggest that vertical transmission is present but not an important route for HCV infection.
Fang
Z
Z
Zhoungfu of Nanjing, Nanjing 210003.
Masashi
M
M
Zhang
X
X
Liu
X
X
Wu
R
R
Wang
D
D
Su
P
P
Zhou
Z
Z
Tang
Y
Y
Li
A
A
D000328:Adult; D005260:Female; D016174:Hepacivirus / Q000235:genetics / Q000276:immunology; D006526:Hepatitis C / Q000235:genetics / Q000635:transmission* / Q000821:virology*; D018937:Hepatitis C Antibodies / Q000097:blood / Q000276:immunology; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D011247:Pregnancy; D012367:RNA, Viral / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D055815:Young Adult
D018937:Hepatitis C Antibodies; D012367:RNA, Viral