Hearing loss and extent of labyrinthine injury in Pseudomonas otitis media.
OBJECTIVE
To determine if the severity of hearing loss due to semicircular canal transection (SCT) in Pseudomonas otitis media (POM) is a function of the extent of the labyrinthine injury.


METHODS
POM was induced bilaterally in 45 guinea pigs. After 2 to 4 days, SCT was performed in one 1 on the horizontal canal, the superior canal, or both the horizontal and the superior canals. Auditory-evoked brainstem responses were measured before and after SCT.


RESULTS
POM was induced bilaterally in all animals. Elevation of click thresholds was found in almost all SCT ears of all 3 groups; however, there were no significant differences between groups. Comparing the SCT ear to the contralateral, control ear, mean hearing losses in the horizontal, superior, and horizontal + superior SCT groups were 23 dB, 27 dB, and 24 dB, respectively.


CONCLUSIONS
Hearing loss does not correlate with extent of labyrinthine injury in POM in the guinea pig.


METHODS
B-2.
Malaty
John
J
Department of Otolaryngology, University of Florida, Gainesville 32610-0264, USA.
Lee
James C
JC
Zhang
Mei
M
Stevens
Gary
G
Antonelli
Patrick J
PJ
D000818:Animals; D005260:Female; D006168:Guinea Pigs; D034381:Hearing Loss / Q000209:etiology*; D015601:Injury Severity Score; D008297:Male; D010033:Otitis Media / Q000150:complications / Q000382:microbiology*; D011552:Pseudomonas Infections / Q000150:complications*; D012665:Semicircular Canals / Q000293:injuries*