title: [Pathological analysis of breast carcinoma after silicone gel injection].
abstract: OBJECTIVE
  To explore the correlation between breast carcinoma and silicone gel injection for breast augmentation.
  
  
  METHODS
  Four cases of breast cancer after silicone gel injection were studied by means of clinical pathological analysis.
  
  
  RESULTS
  In the four women, breast lump of over 5 cm in diameter was found half year to 2 years after silicone injection. The tumor was misdiagnosed to inflammatory reaction of silicone gel injection. Definite diagnosis was made by histological examinations, which showed there was mucoid, light blue and well-distributed silicone gel among the nests of neoplasm cells. Lymph node metastasis of cancer cells was observed.
  
  
  CONCLUSIONS
  Silicone gel injection to the breast may be a reason for evoking or accelerating breast cancer. Breast cancer that occurred after breast augmentation with silicone gel injection could be misdiagnosed. Final diagnosis depends on biopsy. Silicone gel injection for breast augmentation should be abandoned.
authors.affiliation: Department of Pathology, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China.
authors.forename: Guo-qin
authors.initials: GQ
authors.lastname: Chen
authors.forename: Rong
authors.initials: R
authors.lastname: Liu
authors.forename: Ying-ying
authors.initials: YY
authors.lastname: Gu
mesh_terms: D000328:Adult; D001940:Breast / Q000473:pathology / Q000601:surgery; D001943:Breast Neoplasms / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016462:Mammaplasty / Q000009:adverse effects*; D008875:Middle Aged; D020034:Silicone Gels / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D020034:Silicone Gels