Reaction of mouse subcutaneous tissue to Carisolv--a morphologic study.
This study was designed to investigate in vivo subcutaneous tissue reactions after Carisolv contact in a mouse model. Eighteen mice were implanted with two polyethylene tubes: the implant on the right side included a sponge soaked in Carisolv; the implant on the left side served as a control. Similar tissue response was displayed in both test and control groups, suggesting that Carisolv does not result in adverse effects as compared with a control. The tendency of connective tissue encapsulating the implants in both groups may result from the presence of materials that can be well-tolerated by the organism.
Berto
Patrícia Medeiros
PM
Health Science Center, University of Brasilia, Brazil.
Rickli
Anne Caroline
AC
Melo
Camila Silva de Andrade
CS
da Silva
Luciano Paulino
LP
Bezerra
Ana Cristina Barreto
AC
de Toledo
Orlando Ayrton
OA
D000818:Animals; D003737:Dental Cavity Preparation / Q000009:adverse effects; D003764:Dental Materials / Q000633:toxicity*; D005260:Female; D018698:Glutamic Acid / Q000633:toxicity*; D007930:Leucine / Q000633:toxicity*; D008239:Lysine / Q000633:toxicity*; D051379:Mice; D008807:Mice, Inbred BALB C; D040521:Subcutaneous Tissue / Q000187:drug effects*
C119934:Carisolv; D003764:Dental Materials; D018698:Glutamic Acid; D007930:Leucine; D008239:Lysine