title: Is bone marrow trephine biopsy always mandatory in staging Hodgkin's disease?
abstract: We reviewed data from 690 adult patients with Hodgkin's disease (HD) to determine whether bone marrow trephine biopsy (BMTB) is mandatory for all patients. The data suggest that it is not necessary in clinical stage I-IIA. However, bilateral BMTB is recommended in the presence of B symptoms also in patients with localized stage disease.
authors.forename: Elena
authors.initials: E
authors.lastname: Cavalieri
authors.forename: Anna Paola
authors.initials: AP
authors.lastname: Anselmo
authors.forename: Valentina
authors.initials: V
authors.lastname: Gianfelici
authors.forename: Natalia
authors.initials: N
authors.lastname: Frattarelli
authors.forename: Edoardo
authors.initials: E
authors.lastname: Pescarmona
authors.forename: Robin
authors.initials: R
authors.lastname: Foà
authors.forename: Alessandro
authors.initials: A
authors.lastname: Pulsoni
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy / Q000379:methods; D001854:Bone Marrow Cells / Q000473:pathology*; D005260:Female; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods; D019564:Unnecessary Procedures