[Progress of the calcium signal pathway during cardiomyogenesis and cardiomyocyte differentiation].
The process of cardiomyogenesis and cardiomyocyte differentiation in vertebrates is complex, which is controlled by a series of cardiac embryonic genes. The underlying calcium signaling pathways are important to the expression of these genes. The role of calcium dependent transcription process, Ca2+/CaM/CaN/NF AT/GATA 4 transcription pathway and Ca2+/CaM/ CaMK/HDAC/MEF2 transcription pathway, in cardiomyogenesis and cardiomyocyte differentiation are reviewed.
Wang
Yue-Qun
YQ
College of Life Sciences, Hunan Normal University, Changsha, Hunan 410 081, China. yuequnwang@yahoo.com
Liu
Ming-Yao
MY
Wu
Xiu-Shan
XS
D000818:Animals; D002118:Calcium / Q000502:physiology; D020013:Calcium Signaling / Q000235:genetics* / Q000502:physiology; D002147:Calmodulin / Q000235:genetics; D002454:Cell Differentiation / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D032383:Myocytes, Cardiac / Q000166:cytology* / Q000502:physiology; D014157:Transcription Factors / Q000235:genetics*
D002147:Calmodulin; D014157:Transcription Factors; D002118:Calcium