Effect of iron absorption on plasma membrane proteins of small intestinal mucosal cells from iron-deficient rats.
Plasma membrane protein was isolated from small intestinal mucosal cells of normal and iron-deficient rats during iron absorption and examined by acrylamide gel electrophoresis. Two proteins were present in increased amounts in the iron-deficient animals 10 min after administration of iron; uptake studies with 3H-leucine indicated that each had been newly-synthesized. The molecular weights of the proteins were about 60,000 and 300,000.
Kaufman
N
N
Department of Pathology, Queen's University and Kingston General Hospital, Kingston, Ontario, Canada.
Newkirk
M
M
Wyllie
J C
JC
D000821:Animal Feed; D000818:Animals; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D007413:Intestinal Mucosa / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism*; D007421:Intestine, Small / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism*; D007501:Iron / Q000378:metabolism / Q000494:pharmacology*; D000090463:Iron Deficiencies; D008565:Membrane Proteins / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar
D008565:Membrane Proteins; D007501:Iron