[Effect of new hemocorrectors on heart mitochondrial oxidation in hemorrhagic shock].
In experimental model of hemorrhagic shock, the influence of new hemocorrectors, succinasole and sucksivil (1,4-naphtoquinone) on rabbit myocardial mitochondrial oxidation was studied. Both substances improved function of myocardial mitochondria. Administration of new hemocorrectors increased duration of life of animals subjected to hemorrhagic shock, improved hemodynamics, metabolism, normalized myocaidla mitochondrial functions and increased positive effect of shock therapy.
Shevchenko
L I
LI
Ageeva
G R
GR
D000818:Animals; D008297:Male; D008929:Mitochondria, Heart / Q000187:drug effects* / Q000378:metabolism; D009285:Naphthoquinones / Q000494:pharmacology*; D010952:Plasma Substitutes / Q000494:pharmacology*; D011817:Rabbits; D012771:Shock, Hemorrhagic / Q000378:metabolism*; D013386:Succinates / Q000494:pharmacology*
D009285:Naphthoquinones; D010952:Plasma Substitutes; D013386:Succinates; C035342:1,4-naphthoquinone