title: [Experimental hemorheology study on group a whole blood added with group O whole blood].
abstract: The study was to investigate the hemorheologyic changes of group A blood recipient transfused with large amounts of group O whole blood, by erythrocyte count, sympexis index, erythrocyte deformation index, erythrocyte rigid index and whole blood reduced viscosity, 60 ml of group A whole blood were added with 9, 12, 15 and 18 ml of group O whole blood (which corresponds to the 4 000 ml whole blood added with 600, 800, 1 000 and 1 200 ml whole blood). The mixed blood was incubated at 37 degrees C with mixing at 80 times per minute. Samples were taken from the mixed blood at 30 minutes, 2, 4, 8, 12 and 24 hours after culture, and the hemorheology of the mixed whole blood was determined by FASCO-series type 3020B automatic rheograph apparatus. The results showed that there were no differences of erythrocyte count, sympexis index, erythrocyte deformation index, erythrocyte rigid index and whole blood reduced viscosity among all different kinds of mixed whole blood, and there was no difference of sympexis index at different times, but there were obvious differences of erythrocyte count, erythrocyte deformation index, erythrocyte rigid index and whole blood reduced viscosity. It is concluded that blood transfusion of 1,200 ml group O whole blood to a recipient with 50 kg of body weight but with different blood type in emergent situation may exert no harm to the erythrocytes of recipient in a short term.
authors.affiliation: Department of Blood Transfusion, Southwestern Hospital, The Third Military Medical University, Chongqing 400038, China.
authors.forename: Rui-Qing
authors.initials: RQ
authors.lastname: Xiao
authors.forename: Shu-Ming
authors.initials: SM
authors.lastname: Zhao
authors.forename: Wu-Cun
authors.initials: WC
authors.lastname: Lin
authors.forename: Jie
authors.initials: J
authors.lastname: Zeng
authors.forename: Ying
authors.initials: Y
authors.lastname: Chen
authors.forename: Ru-Fu
authors.initials: RF
authors.lastname: Xu
authors.forename: Hui
authors.initials: H
authors.lastname: Guo
authors.forename: Jing-Han
authors.initials: JH
authors.lastname: Liu
mesh_terms: D000017:ABO Blood-Group System; D001787:Blood Group Incompatibility / Q000097:blood / Q000517:prevention & control; D001803:Blood Transfusion; D004906:Erythrocyte Count; D004912:Erythrocytes / Q000166:cytology; D005434:Flow Cytometry / Q000295:instrumentation / Q000379:methods; D006439:Hemodynamics; D018056:Hemorheology; D006801:Humans
chemical_list: D000017:ABO Blood-Group System