title: Pelvic drainage and other risk factors for leakage after elective anterior resection in rectal cancer patients: a prospective study of 978 patients.
abstract: OBJECTIVE
  The objective of this study was to investigate prophylactic pelvic drainage and other factors that might be associated with anastomotic leakage after elective anterior resection of primary rectal cancer.
  
  
  BACKGROUND
  Anastomotic leak after anterior resection for primary rectal cancer leads to significant postoperative morbidity and mortality. The role of pelvic drainage in the prevention of anastomotic leakage is controversial.
  
  
  METHODS
  We investigated 978 consecutive patients undergoing elective anterior resection for primary rectal cancer between February 1995 and December 1998 in a single institution. Use of a drain and type of drainage were at the surgeon's preference. Data were prospectively collected during hospitalization. Twenty-five independent tumor-, patient-, and treatment-related variables were analyzed. The dependent variable was clinical anastomotic leakage. A binary logistic regression analysis was used to assess the independent association of variables with the dependent variable.
  
  
  RESULTS
  The clinical anastomotic leakage rate was 2.8%. Independent risk factors for anastomotic leakage were use of an irrigation-suction drain (odds ratio [OR], 9.13; 95% confidence interval [CI], 1.16-71.76), blood transfusion, poor colon preparation (OR, 2.58; 95% CI, 1.10-5.88), and anastomotic level 5 cm or less from the anal verge (OR, 2.38; 95% CI, 1.03-5.46).
  
  
  CONCLUSIONS
  Routine use of pelvic drainage is not justified and should be discouraged. In cases in which pelvic drainage is required such as in difficult operations or to prevent pelvic hematoma, pelvic drainage other than irrigation-suction should be considered.
authors.affiliation: Department of Surgery, Colorectal Section of Chang Gung Memorial Hospital, at Linko, Taiwan.
authors.forename: Chien Yuh
authors.initials: CY
authors.lastname: Yeh
authors.forename: Chung Rong
authors.initials: CR
authors.lastname: Changchien
authors.forename: Jeng-Yi
authors.initials: JY
authors.lastname: Wang
authors.forename: Jinn-Shiun
authors.initials: JS
authors.lastname: Chen
authors.forename: Hong Hwa
authors.initials: HH
authors.lastname: Chen
authors.forename: Jy-Ming
authors.initials: JM
authors.lastname: Chiang
authors.forename: Reiping
authors.initials: R
authors.lastname: Tang
mesh_terms: D000714:Anastomosis, Surgical / Q000009:adverse effects; D003082:Colectomy / Q000009:adverse effects*; D004322:Drainage / Q000009:adverse effects* / Q000295:instrumentation; D005260:Female; D006801:Humans; D008297:Male; D010388:Pelvis; D011446:Prospective Studies; D012004:Rectal Neoplasms / Q000601:surgery*; D012307:Risk Factors; D013529:Surgical Wound Dehiscence / Q000175:diagnosis / Q000209:etiology*; D016896:Treatment Outcome