title: AIDS, multicentric Castleman's disease, and plasmablastic leukemia: report of a long-term survival.
abstract: Plasmablastic leukemia (PL) as a complication of human herpes virus 8 (HHV8)-associated Castleman's disease is marked by a rapid and fatal outcome. In patients with AIDS, survival of 7 to 14 days after diagnosis has been reported. Prompt splenectomy and chemotherapy might lead to a significant survival benefit. Here we report a case of long-term survival in a patient with AIDS and multicentric Castleman's disease (MCD) complicated by PL.
authors.affiliation: Medical Policlinic, Pettenkoferstr. 8a, D-80336 Munich, Germany. sophiahorster@gmx.de
authors.forename: S
authors.initials: S
authors.lastname: Horster
authors.forename: C
authors.initials: C
authors.lastname: Jung
authors.forename: C
authors.initials: C
authors.lastname: Zietz
authors.forename: C D
authors.initials: CD
authors.lastname: Cohen
authors.forename: M
authors.initials: M
authors.lastname: Siebeck
authors.forename: F D
authors.initials: FD
authors.lastname: Goebel
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000821:virology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005871:Castleman Disease / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D006566:Herpesviridae Infections / Q000209:etiology*; D019288:Herpesvirus 8, Human; D006801:Humans; D007952:Leukemia, Plasma Cell / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D008297:Male; D013156:Splenectomy