title: Chemical modifications of bile acids under high-intensity ultrasound or microwave irradiation.
abstract: High-intensity ultrasound (HIU) and microwave (MW) irradiation, having emerged as effective promoters of organic reactions, were exploited for the synthesis of bile acids derivatives. Esterification, amidation, hydrolysis, oxidation, and reduction were investigated. Compared to conventional methods, both techniques proved much more efficient, increasing product yields and dramatically cutting down reaction times. Scaled-up studies are now under way.
authors.affiliation: Dipartimento di Scienza e Tecnologia del Farmaco, Università di Torino, Via Giuria 9, 10125 Torino, Italy. giancarlo.cravotto@unto.it
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Cravotto
authors.forename: Luisa
authors.initials: L
authors.lastname: Boffa
authors.forename: Marta
authors.initials: M
authors.lastname: Turello
authors.forename: Massimo
authors.initials: M
authors.lastname: Parenti
authors.forename: Alessandro
authors.initials: A
authors.lastname: Barge
mesh_terms: D001647:Bile Acids and Salts / Q000737:chemistry* / Q000528:radiation effects*; D008872:Microwaves; D008968:Molecular Conformation; D014465:Ultrasonics
chemical_list: D001647:Bile Acids and Salts