title: Prevalence of hepatitis C infection in patients with non-Hodgkin's lymphoma in South Florida and review of the literature.
abstract: The etiology of non-Hodgkin's lymphoma is unknown in the majority of the cases. Although Epstein-Barr virus, human T-cell leukemia-lymphoma virus and human herpes virus-8 have been established as casual agents in the pathogenesis of specific types of lymphoma, the role of hepatitis C virus (HCV) in lymphomagenesis remains controversial, with marked geographic variability. We conducted an epidemiologic study to evaluate the prevalence of hepatitis C virus infection in patients with lymphoma in South Florida. Ninety consecutive patients with lymphoma and 96 consecutive control patients with solid tumors were tested for HCV. HCV infection was detected in 2 patients with NHL (2.2%) and in 4 control patients (4.1%). Our study does not support the association between HCV and lymphoma in South Florida, US.
authors.affiliation: Division of Hematology-Oncology, Department of Medicine Sylvester Comprehensive Cancer Center Miami, Florida 33136, USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: Morgensztern
authors.forename: Manuel
authors.initials: M
authors.lastname: Rosado
authors.forename: Orlando
authors.initials: O
authors.lastname: Silva
authors.forename: Edgardo
authors.initials: E
authors.lastname: Santos
authors.forename: Sakher
authors.initials: S
authors.lastname: Abdullah
authors.forename: Mark
authors.initials: M
authors.lastname: Goodman
authors.forename: Kara
authors.initials: K
authors.lastname: Hamilton-Nelson
authors.forename: Joseph
authors.initials: J
authors.lastname: Rosenblatt
authors.forename: Izidore
authors.initials: I
authors.lastname: Lossos
mesh_terms: D016022:Case-Control Studies; D005260:Female; D005431:Florida / Q000453:epidemiology; D006526:Hepatitis C / Q000150:complications* / Q000453:epidemiology* / Q000473:pathology / Q000821:virology; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D044469:Racial Groups