Assessing and managing chemotherapy-induced mucositis pain.
Acute pain is the major clinical problem associated with mucositis. Mucosal tissue injury is a dose-limiting toxicity of many cancer therapies. Because the number of patients treated with combinations of high-dose chemotherapy agents is likely to increase, more patients are at risk for mucositis. Currently, no consensus exists regarding mucositis prevention, assessment, or treatment. Similarly, research is needed in methods to accurately assess and manage pain for mucositis. Multiple interventional approaches are needed to decrease the emotional and physical distress caused by acute oral pain and mucositis. An assessment tool that includes physical, functional, and pain parameters is presented. Although approaches to prevent and treat mucositis are increasing, appropriate assessment and timely directed interventions can minimize patient distress.
Harris
Debra J
DJ
School of Nursing, Yale University, New Haven, CT, USA. debrajean_harris@yahoo.com
Knobf
M Tish
MT
D000203:Activities of Daily Living; D000698:Analgesia / Q000379:methods / Q000451:nursing; D000700:Analgesics / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001294:Attitude to Health; D006801:Humans; D009061:Mouth Mucosa; D009067:Mouthwashes / Q000627:therapeutic use; D024802:Nurse's Role; D009730:Nursing Assessment / Q000379:methods*; D009859:Oncology Nursing / Q000379:methods; D009910:Oral Hygiene / Q000379:methods / Q000451:nursing; D010146:Pain / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control; D010147:Pain Measurement / Q000379:methods* / Q000451:nursing; D010347:Patient Care Planning; D010353:Patient Education as Topic / Q000379:methods; D011788:Quality of Life; D018570:Risk Assessment; D012307:Risk Factors; D013280:Stomatitis / Q000139:chemically induced / Q000150:complications / Q000451:nursing / Q000523:psychology; D013315:Stress, Psychological / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control
D000700:Analgesics; D000970:Antineoplastic Agents; D009067:Mouthwashes