title: Effects of septoplasty and septal deviation on nasal mucociliary clearance.
abstract: To evaluate the effect of septal pathology and surgery on nasal mucociliary clearance. A radioisotope method was used to measure the velocity of nasal mucociliary transport. Nasal mucociliary clearance was measured before and after septal surgery using technetium-99m macroaggregated albumin. Fifteen patients (mean age: 20 +/- 8 years; 11 males, four females) were studied pre-operatively, but scintigraphy could be repeated only in 10 patients, 2 months after surgery. A group of 10 healthy volunteers were also studied. The clearance values obtained from the preoperative period (26.25 +/- 9.45 min) were significantly higher than those of the post-operative period (15.05 +/- 6.35 min). The values obtained of control group (13.30 +/- 3.15 min) were not significantly different from the post-operative values of the patient group. Septal deviation affects the mucociliary activity. It is improved by surgery. This study showed that nasal septal deviation reduced the nasal mucociliary activity, and this can easily evaluated with scintigraphy.
authors.affiliation: Department of Nuclear Medicine, Atatürk University Medical School, Erzurum, Turkey. uslusinav@hotmail.com
authors.forename: H
authors.initials: H
authors.lastname: Uslu
authors.forename: C
authors.initials: C
authors.lastname: Uslu
authors.forename: E
authors.initials: E
authors.lastname: Varoglu
authors.forename: M
authors.initials: M
authors.lastname: Demirci
authors.forename: B
authors.initials: B
authors.lastname: Seven
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D009079:Mucociliary Clearance / Q000502:physiology*; D009300:Nasal Septum / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000601:surgery; D011300:Preoperative Care / Q000379:methods; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; D016896:Treatment Outcome
chemical_list: D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin