title: Postirradiation sarcoma: a case report and current review.
abstract: Irradiation-induced sarcomas are well-known potential late sequelae of radiation therapy. These tumors are very aggressive and often elude early detection and timely intervention, rapidly leading to early demise of afflicted patients. Long-term patient follow-up and a high index of suspicion are crucial for timely intervention. In this report, we present a case of irradiation-induced osteosarcoma involving the mandible. Diagnostic and therapeutic considerations are subsequently discussed.
authors.affiliation: Division of Head and Neck Surgery, UCLA School of Medicine, Los Angeles, CA 90095-1624, USA.
authors.forename: Ellie G
authors.initials: EG
authors.lastname: Maghami
authors.forename: Maie
authors.initials: M
authors.lastname: St-John
authors.forename: Sunita
authors.initials: S
authors.lastname: Bhuta
authors.forename: Elliot
authors.initials: E
authors.lastname: Abemayor
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D002277:Carcinoma / Q000532:radiotherapy; D006801:Humans; D008297:Male; D008334:Mandible / Q000528:radiation effects / Q000601:surgery; D008339:Mandibular Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D012516:Osteosarcoma / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D014067:Tonsillar Neoplasms / Q000532:radiotherapy; D016896:Treatment Outcome