title: High doses of acyclovir: a new concept in the treatment of neonatal herpes simplex virus infection.
abstract: The authors present a case of a preterm newborn with congenital infection of herpes simplex virus type 2. The patient was treated with newly recommended high intravenous doses of acyclovir. It can be supposed that it reduces mortality, but the high morbidity continues to be a problem.
authors.affiliation: Neonatal Intensive Care Unit, Institute for the Care of Mother and Child, and 3rd School of Medicine, Charles University, Prague, Czech Republic
authors.forename: Jan
authors.initials: J
authors.lastname: Melichar
authors.forename: Jan
authors.initials: J
authors.lastname: Miletin
authors.forename: Jan
authors.initials: J
authors.lastname: Janota
authors.forename: Jáchym
authors.initials: J
authors.lastname: Kucera
authors.forename: Václav
authors.initials: V
authors.lastname: Cunat
authors.forename: Petra
authors.initials: P
authors.lastname: Sanáková
authors.forename: Zbynek
authors.initials: Z
authors.lastname: Stranák
mesh_terms: D000212:Acyclovir / Q000008:administration & dosage*; D018792:Encephalitis, Viral / Q000188:drug therapy*; D006561:Herpes Simplex / Q000188:drug therapy*; D018258:Herpesvirus 2, Human; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000188:drug therapy*
chemical_list: D000212:Acyclovir