title: [RNA-based transgene silencing: mechanism and applications].
abstract: RNA-based transgene silencing is a phenomenon that endogenous and exogenous mRNAs are degraded specifically directed by double-stranded RNA. Here we review the recent advances on its mechanism and summarize related proteins and expatiate their functions. Furthermore,we introduce the enormous potential of dsRNA as a tool in functional genomics research and practical biotechnology.
authors.affiliation: Biology Department, Capital Normal Universit, Beijing 100037, China.
authors.forename: Wen
authors.initials: W
authors.lastname: Chen
authors.forename: Dong
authors.initials: D
authors.lastname: Wang
authors.forename: Yi-Kun
authors.initials: YK
authors.lastname: He