[Information behavior of 7 STR loci on chromosome 9p in gene scanning].
To get genotype and allele frequency distributions of seven short tandem repeat (STR) loci of chromosome 9p,D9S288,D9S157,D9S1748,D9S171,D9S161,D9S1817 and D9S1805 in Chinese Han population in Hunan area,blood samples were collected from the random Han individual in Hunan and the whole genomic DNA was extracted.STR loci were amplified by multiplex-PCR technique and genotyped by ABI 377 sequencer.Seventy-five alleles were detected,with frequencies ranging from 0.002 to 0.800,and constituted 243 genotypes. All the seven loci met Hardy-Weinberg equilibrium. The statistical analysis of seven STR loci showed H(heterozygosity) ranging from 0.347 to 0.844,DP(discrimination power) ranging from 0.346 to 0.841,PPE(probabilities of paternity exclusion) ranging from 0.308 to 0.738 and PIC(polymorphic information content) ranging from 0.328 to 0.822. The result indicated that there was a significant difference between Han ethnic group and the white and the black.
Zeng
Zhao-Yang
ZY
Cancer Research Institute, Xiangya Medical School, Central South University, Changsha 410078, China. zengzhaoyang@163.net
Xiong
Wei
W
Xiong
Fang
F
Shen
Shou-Rong
SR
Li
Xiao-Ling
XL
Li
Wei-Fang
WF
Wang
Rong
R
Xiao
Bing-Yi
BY
Fan
Song-Qing
SQ
Huang
He
H
Zhou
Ming
M
Li
Gui-Yuan
GY