title: Synthesis of 2,3-disubstituted indole on solid phase by the Fischer indole synthesis.
abstract: 2,3-Disubstituted indoles were synthesized by solid-phase reaction using the Fischer indole synthesis. A "traceless" silicon linker was employed with the silicon-carbon bonding being cleaved with TFA. An oxygen atom was placed into the middle of the spacer/linker so as to enhance solid-phase synthesis by better solvation.
authors.affiliation: College of Pharmacy, Kyung Hee University, Seoul 130-701, Korea.
authors.forename: Han-Seo
authors.initials: HS
authors.lastname: Mun
authors.forename: Won-Hun
authors.initials: WH
authors.lastname: Ham
authors.forename: Jin-Hyun
authors.initials: JH
authors.lastname: Jeong
mesh_terms: D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D007211:Indoles