Triterpenes from Maesopsis eminii.
Two pentacyclic triterpenes, 1alpha,3beta-dihydroxybauer-7-en-28-oic acid (1) and 3beta-hydroxybauer-7-en-28-oic acid (2), together with sitosterol-3-beta-O-d-glucopyranoside and stigmasterol have been isolated from the bark of the plant Maesopsis eminii. Their structures have been elucidated by spectroscopic methods. One of the triterpenes (1) is new, and its structure was confirmed by X-ray crystallographic analysis. This new triterpene displayed moderate antibacterial activity against Bacillus subtilis ATCC 6633.
Fokou
Patrice Aimé
PA
Department of Chemistry, University of Bielefeld, PO Box 100131, 33501 Bielefeld, Germany.
Stammler
Hans-Georg
HG
Neumann
Beate
B
Huber
Thomas
T
Lontsi
David
D
Wangun
Hilaire V Kemami
HV
Sewald
Norbert
N
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D002163:Cameroon; D018360:Crystallography, X-Ray; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D024301:Plant Bark / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D027823:Rhamnaceae / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
C497306:1alpha,3beta-dihydroxybauer-7-en-28-oic acid; C497307:3beta-hydroxybauer-7-en-28-oic acid; D000900:Anti-Bacterial Agents; D014315:Triterpenes