title: Comparison of differing C-reactive protein assay methods and their impact on cardiovascular risk assessment.
abstract: A medium-sensitivity assay for C-reactive protein (CRP) was compared with a high-sensitivity, enhanced immunoturbidimetric assay in 803 angiographically studied patients. Different absolute CRP values were found by the assays, but there was a high correlation by quartile rank and similar predictive values for death and myocardial infarction. This suggests that the conclusions of previous studies performed using the medium-sensitivity assay are still valid but that cross-study comparisons should use percentile rank.
authors.affiliation: Cardiovascular Department, LDS Hospital, Salt Lake City, Utah 84143, USA.
authors.forename: Jessica L
authors.initials: JL
authors.lastname: Clarke
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Anderson
authors.forename: John F
authors.initials: JF
authors.lastname: Carlquist
authors.forename: Richard F
authors.initials: RF
authors.lastname: Roberts
authors.forename: Benjamin D
authors.initials: BD
authors.lastname: Horne
authors.forename: Tami L
authors.initials: TL
authors.lastname: Bair
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Kolek
authors.forename: Chrissa P
authors.initials: CP
authors.lastname: Mower
authors.forename: Ashle M
authors.initials: AM
authors.lastname: Crane
authors.forename: William L
authors.initials: WL
authors.lastname: Roberts
authors.forename: Joseph B
authors.initials: JB
authors.lastname: Muhlestein
mesh_terms: D001774:Blood Chemical Analysis / Q000379:methods; D002097:C-Reactive Protein / Q000032:analysis*; D003324:Coronary Artery Disease / Q000097:blood* / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000175:diagnosis; D011237:Predictive Value of Tests; D018570:Risk Assessment; D012680:Sensitivity and Specificity
chemical_list: D002097:C-Reactive Protein