Recurrent Staphylococcus aureus chalazia in hyperimmunoglobulinemia E (Job's) syndrome.
OBJECTIVE
To report a case of recurrent Staphylococcus aureus chalazia in a patient with hyperimmunoglobulinemia E syndrome (Job's Syndrome).


METHODS
Case report.


METHODS
Three separate surgical incisions and curettages of multiple, recurrent chalazia of the right upper eyelid were performed over a course of 3 months. Cultures and pathologic specimens were obtained. Postoperative treatment consisted of oral erythromycin and amoxicillin/clavulonate, topical tobramycin/dexamethasone ointment, and warm compresses.


RESULTS
Pathology of the tarsus confirmed the diagnosis of multiple chalazia. Cultures of the chalazia contents were positive for Staphylococcus aureus. No further recurrence was observed following the third surgical procedure over a 3-month follow-up period.


CONCLUSIONS
Characteristic Staphylococcus aureus skin infections in immunodeficient patients with hyperimmunoglobulinemia E syndrome can involve the eyelids and may be recurrent despite appropriate medical and surgical therapy.
Destafeno
John J
JJ
Department of Ophthalmology, Long Island Jewish Medical Center, North Shore-Long Island Jewish Health System, Great Neck, New York 11021, USA. jdestafeno@yahoo.com
Kodsi
Sylvia R
SR
Primack
Jonathan D
JD
D000293:Adolescent; D000900:Anti-Bacterial Agents; D017043:Chalazion / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D005260:Female; D006801:Humans; D007589:Job Syndrome / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D013508:Ophthalmologic Surgical Procedures; D012008:Recurrence; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D013211:Staphylococcus aureus / Q000302:isolation & purification*
D000900:Anti-Bacterial Agents