title: [Influence of LASIK on retinal nerve fiber layer].
abstract: OBJECTIVE
  To study the influence of laser-assisted in situ keratomileusis (LASIK) on retinal nerve fibre layer (RNFL) thickness.
  
  
  METHODS
  50 myopic eyes treated with uncomplicated LASIK. Measurement of preoperatory and postoperatory (2 weeks) peripapillary RNFL thickness by optical coherence tomography (OCT).
  
  
  METHODS
  mean, superior, inferior, nasal and temporal thickness. Statistical comparison between preoperatory and postoperatory values. Study of the correlation between the amount of myopia and RNFL thickness.
  
  
  RESULTS
  There were no statistical differences between preoperatory and postoperatory RNFL thickness values in any of the studied variables: mean (77.6 SD 14 vs 81 SD 13,3), superior (103.1 SD 22,6 vs 105.4 SD 24.6), inferior (89.3 SD 28 vs 93.9 SD 23.1), nasal (53.7 SD 18.1 vs 56.1 SD 16) and temporal thickness (64.74 SD 12.29 vs 67.3 SD 13.7) (P > 0.05 for all comparisons; Student's t test). There was an inverse correlation between the amount of myopia and RNFL thickness in all of the studied variables: mean (r= -0.45), superior (r= -0.42), inferior (r=-0.39), nasal (r= -0.26) and temporal thickness (r= -0.09) (Pearson's test).
  
  
  CONCLUSIONS
  OCT-measured RNFL thickness remains unchanged after LASIK in the follow-up period.
authors.affiliation: Instituto Clínico-Quirúrgico de Oftalmología (ICQO), San Sebastián, Spain. irodrig@euskalnet.net
authors.forename: I
authors.initials: I
authors.lastname: Rodríguez-Agirretxe
authors.forename: M
authors.initials: M
authors.lastname: García Gómez de Segura
authors.forename: J
authors.initials: J
authors.lastname: Etxebarria Ecenarro
authors.forename: M
authors.initials: M
authors.lastname: Dios Castro
mesh_terms: D000328:Adult; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D008875:Middle Aged; D009216:Myopia / Q000473:pathology* / Q000601:surgery*; D012160:Retina / Q000473:pathology*