title: Malignant myoepithelioma of the salivary gland--an untypical clinical course.
abstract: A case of malignant tumor developing from myoepithelial cells (malignant myoepithelioma) is presented. The primary focus was located in the region of the left submandibular salivary gland. A relapse and metastases were disclosed in the same salivary gland, in the lung and the left breast. Immunohistochemical studies demonstrated positive reactions for S-100 protein, cytokeratins, smooth muscle actin, vimentin, GFAP protein, p53 protein and Ki-67 antigen, and allowed for establishing the final histopathological diagnosis of malignant myoepithelioma.
authors.affiliation: Department of Pathomorphology, Lower Silesia Center of Oncology, Wrocław.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Rzeszutko
authors.forename: Piotr
authors.initials: P
authors.lastname: Kasprzak
authors.forename: Piotr
authors.initials: P
authors.lastname: Dziegiel
authors.forename: Marta
authors.initials: M
authors.lastname: Rzeszutko
authors.forename: Mirosław
authors.initials: M
authors.lastname: Sopel
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001943:Breast Neoplasms / Q000556:secondary / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009208:Myoepithelioma / Q000737:chemistry / Q000556:secondary* / Q000601:surgery; D009364:Neoplasm Recurrence, Local; D013365:Submandibular Gland Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor