[Method for the calculation of the 50% effective dose of biologically active agents].
A newly proposed method for the mathematical and graphic determination and calculation of ED50 (LD50) on the abscissa at the meeting point of the cumulate of dead and the cumulate of survived animals (in absolute figures) in "dose-effect) experiments is described. "The method of meeting cumulates) for the calculation of ED50 (LD50) is simple, eliminates unnecessary calculations, yields results, highly similar (95-100%) to those obtained by other methods and may be used in different medico-biological studies.
Kuznetsov
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D000818:Animals; D004195:Disease Models, Animal; D006801:Humans; D007928:Lethal Dose 50; D008433:Mathematics; D051379:Mice; D015011:Yersinia pseudotuberculosis; D015012:Yersinia pseudotuberculosis Infections / Q000382:microbiology*