[Differentially expressed genes in prostate cancer and benign prostatic hyperplasia].
OBJECTIVE
To detect and analyze the differentially expressed genes in prostate cancer (PCa) and benign prostatic hyperplasia (BPH).


METHODS
Oligonucleotide microarray containing 465 genes was used to investigate the differentially expressed genes in PCa and BPH.


RESULTS
There were 35 differentially expressed genes between PCa and BPH, of which 17 were up-regulated and 18 down-regulated in PCa.


CONCLUSIONS
The study of the differentially expressed genes in PCa and BPH should help to understand the molecular mechanism of PCa and identify the markers for diagnostic and therapeutic use.
Zhang
Tong
T
Department of Urology, the Second Hospital of Tianjin Medical University, Tianjin 300211, China.
Xu
Yong
Y
Tang
Hua
H
Liu
Min
M
Ren
Dalin
D
Niu
Yuanjie
Y
D015536:Down-Regulation; D020869:Gene Expression Profiling; D006801:Humans; D008297:Male; D020411:Oligonucleotide Array Sequence Analysis; D011470:Prostatic Hyperplasia / Q000235:genetics / Q000378:metabolism*; D011471:Prostatic Neoplasms / Q000235:genetics / Q000378:metabolism*; D015854:Up-Regulation