Asymmetric synthesis of both the enantiomers of trans-3-hydroxypipecolic acid.
Both the enantiomers of trans-3-hydroxypipecolic acid have been synthesized employing the Sharpless asymmetric dihydroxylation and epoxidation as the key steps starting from a commercially available starting material 1,4-butanediol.
Kumar
Pradeep
P
Division of Organic Chemistry: Technology, National Chemical Laboratory, Pune 411 008, India. tripathi@dalton.ncl.res.in
Bodas
Mandar S
MS