[Photodynamic therapy for treatment of choroidal neovascularization].
OBJECTIVE
To evaluate the efficacy of photodynamic therapy with photodynamic therapy (PDT) in the management of choroidal neovascularization (CNV) in age-related macular degeneration (AMD) and myopia.


METHODS
102 eyes with subfoveal or yuxtafoveal CNV underwent visual acuity (VA) testing, ophthalmic examination, and fluorescein angiography. Retreatment of persistent CNV was done after three months.


RESULTS
CNV was caused by AMD in 75.5% of patients, pathologic myopia in 24.5%. Follow up ranged from 9 to 33 months (mean: 15.94 months). 88% of CNV caused by pathologic myopia was classic and 40% was in lesions caused by AMD. CNV survival was shorter in lesions caused by pathologic myopia with a significant difference (p=0.0018). VA improved in 48% of lesions caused by pathologic myopia and in 28.6% of lesions caused by AMD. We did not observe any severe complication caused by PDT.


CONCLUSIONS
PDT is a moderately effective treatment without complications in treating subfoveal CNV.
Pérez Oliván
S
S
Servicio de Oftalmología, Hospital Universitario Miguel Servet, Zaragoza, Spain. sperezo@able.es
Torrón Fernández-Blanco
C
C
Ferrer Novella
E
E
Ruiz-Moreno
O
O
Honrubia
F M
FM
D000368:Aged; D020256:Choroidal Neovascularization / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D008268:Macular Degeneration / Q000150:complications; D008297:Male; D009216:Myopia / Q000150:complications; D010778:Photochemotherapy