[Cellular immunity in childhood iron deficiency anemia with recurrent respiratory infections].
OBJECTIVE
To examine interleukin-2 (IL-2) activity,serum soluble IL-2 receptor (sIL-2R) level and T lymphocyte subsets in peripheral blood from 63 childhood iron deficiency anemia (IDA) patients with recurrent respiratory infections(RRI).


METHODS
IL-2 activity, sIL-2R level and T lymphocyte subsets were assayed by MTT, ELISA and APAAP, respectively.


RESULTS
IL-2 activity, percentages of CD3+ and CD4+ cells as well as the ratio of CD4+/ CD8+ cells in the patients were significantly lower ( P < 0.01),while sIL-2R levels were higher than that in normal controls (P < 0.01). No significant change was found in the percentage of CD8+ cells.


CONCLUSIONS
Cellular immunity was impaired in childhood IDA with RRI.
Liu
W
W
PLA No. 60 Hospital, Yunnan Dali 671003.
Jiang
A
A
Guo
C
C
D018798:Anemia, Iron-Deficiency / Q000150:complications* / Q000276:immunology* / Q000378:metabolism; D015704:CD4 Antigens / Q000378:metabolism; D016827:CD8 Antigens / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007223:Infant; D007376:Interleukin-2 / Q000378:metabolism; D008297:Male; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000150:complications* / Q000276:immunology* / Q000378:metabolism
D015704:CD4 Antigens; D016827:CD8 Antigens; D007376:Interleukin-2