Fast contralateral propagation of after-discharges induced by stimulation of medial temporal lobe.
In a patient with unilateral hippocampal sclerosis, stimulation of the contralateral anterior perirhinal cortex triggered after-discharges in the sclerotic hippocampus, followed in one case by a seizure. The spatial and temporal characteristics of these responses reveal fast interconnections between the two medial temporal lobes.
Adam
Claude
C
Neurology 1, Epileptology Unit, Hôpital de La Pitié-Salpêtrière, Paris, France. claude.adam@psl.ap-hop-paris.fr
Hasboun
Dominique
D
Clemenceau
Stéphane
S
Dupont
Sophie
S
Baulac
Michel
M
Hazemann
Paule
P
D004558:Electric Stimulation; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis* / Q000503:physiopathology*; D007839:Functional Laterality; D006624:Hippocampus / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012598:Sclerosis; D013702:Temporal Lobe / Q000473:pathology / Q000503:physiopathology*