title: Cerebral near-infrared spectroscopy in adult heart surgery: systematic review of its clinical efficacy.
abstract: OBJECTIVE
  This systematic review is aimed at answering the following questions: 1) Is near-infrared spectroscopy (NIRS) clinically effective in detecting cerebral desaturation during heart surgery? 2) Are these results based on studies with solid methodology?
  
  
  METHODS
  MEDLINE, internet, and hand searches up to February 2004 for English and French papers on NIRS.
  
  
  RESULTS
  Forty-eight papers were retrieved, with a total of 5,931 cardiac surgery patients monitored by NIRS. More than 83% of patients underwent coronary artery bypass graft surgery. The majority of studies were prospective for the monitored group. Clinically, NIRS monitoring appears to detect brain desaturation episodes encountered during surgery. However, the majority of studies retrieved suffered from major methodological limitations and a low level of evidence. NIRS validity vs jugular bulb oximetry is questioned together with its predictive value in identifying those who will suffer postoperatively from neurological deficits. The sole randomized controlled trial appears to have recorded negative results in this respect.
  
  
  CONCLUSIONS
  The clinical application of NIRS in heart surgery as a brain-monitoring device seems interesting. However, NIRS has to be investigated more rigorously to prove its clinical utility in cardiac surgery.
authors.affiliation: Department of Anesthesiology, Montreal Heart Institute, Room R-2230, 5000 Belanger Street, Montreal, Quebec H1T 1C8, Canada. Marie-Christine.Taillefer@icm-mhi.org
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Taillefer
authors.forename: André Y
authors.initials: AY
authors.lastname: Denault
mesh_terms: D000328:Adult; D001923:Brain Chemistry; D006348:Cardiac Surgical Procedures; D002986:Clinical Trials as Topic; D006801:Humans; D016343:Monitoring, Intraoperative / Q000379:methods*; D010100:Oxygen / Q000097:blood; D012107:Research Design; D019265:Spectroscopy, Near-Infrared
chemical_list: D010100:Oxygen