[Study on the clinical and biological characteristics of 20 cases of chronic lymphoid leukemias].
OBJECTIVE
To further define the chronic lymphoid leukemia (CLL).


METHODS
Tweenty cases of CLL classified after the FAB proposals (1989) were retrospectively analyzed.


RESULTS
Based on the clinical features, cell/tissue morphology, immunophenotype, IgH and TCR gamma gene rearrangement serum or urine immunoglobulin levels, 16 cases of B-lymphoid leukemia (12 of CLL, 1 of PLL, 2 of leukemia/lymphoma, and 1 of WM) as well as 4 cases of T-lymphoid leukemia (2 of leukemia/lymphoma, 1 of T-LGLL, and 1 of NK-LGLL) were identified. The diagnostic criteria,cell morphology,biological characteristics and prognosis for CLL were discussed.


CONCLUSIONS
T-leukemia/lymphoma should be incorporated in the classification of CLL.
Sheng
R
R
First Affiliated Hospital of Nanjing Medical University, Nanjing.
Zhu
G
G
Xia
W
W
Wu
Y
Y
Li
J
J
Zhang
J
J
D002908:Chronic Disease; D005455:Fluorescent Antibody Technique; D015321:Gene Rearrangement; D006801:Humans; D007136:Immunoglobulins / Q000097:blood / Q000652:urine; D016130:Immunophenotyping; D007945:Leukemia, Lymphoid / Q000145:classification* / Q000175:diagnosis / Q000235:genetics / Q000276:immunology; D011379:Prognosis; D012189:Retrospective Studies
D007136:Immunoglobulins