title: Endothelial microparticles and the diagnosis of the vasculitides.
abstract: Recently there has been considerable interest in a novel surrogate marker of endothelial injury, endothelial microparticles (EMP), in a number of diseases characterised by endothelial injury. This review examines the data relating to EMP in human disease states, and examines the potential for EMP to provide a window onto the activated endothelium in primary systemic vasculitides. The utility of EMP for the diagnosis and monitoring of active vasculitis is discussed.
authors.affiliation: Department of Nephrourology, Institute of Child Health, London.
authors.forename: Paul A
authors.initials: PA
authors.lastname: Brogan
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Dillon
mesh_terms: D015415:Biomarkers / Q000032:analysis; D001792:Blood Platelets / Q000378:metabolism; D004730:Endothelium, Vascular / Q000378:metabolism*; D006801:Humans; D014657:Vasculitis / Q000175:diagnosis* / Q000378:metabolism
chemical_list: D015415:Biomarkers