A two-step reaction sequence for the syntheses of tetrahydronaphthalenes.
[Reaction: see text] A cobalt(I)-catalyzed Diels-Alder reaction of a boron-functionalized enyne is the key step in a two-step reaction cascade interconnecting four simple starting materials to obtain polycyclic multifunctionalized products in good yields and with a very high degree of diastereoselectivity.
Hilt
Gerhard
G
Fachbereich Chemie, Philipps-Universität Marburg, Hans-Meerwein-Strasse, 35032 Marburg, Germany. hilt@chemie.uni-marburg.de
Lüers
Steffen
S
Smolko
Konstantin I
KI
D000480:Alkynes / Q000737:chemistry; D001896:Boron Compounds / Q000737:chemistry*; D003035:Cobalt / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D013764:Tetrahydronaphthalenes / Q000138:chemical synthesis* / Q000737:chemistry
D000480:Alkynes; D001896:Boron Compounds; D013764:Tetrahydronaphthalenes; D003035:Cobalt