title: Metastasis of malignant peripheral nerve sheath tumor to free vascularized myocutaneous flap.
abstract: The vascularized free myocutaneous flap graft, a recent advance in microsurgery, is a very useful reconstruction technique for covering massive soft tissue defects or muscular dysfunction caused by wide resection for malignant soft tissue tumors. We have used this technique to treat many patients after resection for malignant soft tissue tumors. Recently we encountered a case in which a malignant peripheral nerve sheath tumor (MPNST) metastasized to a vascularized free myocutaneous flap used for limb reconstruction surgery after wide resection of a primary lesion. To our knowledge, there have been no previous reports of metastasis of a malignant soft tissue tumor (or any other cancer) to a grafted cutaneous or myocutaneous flap.
authors.affiliation: Department of Orthopaedic Surgery, Mie University Faculty of Medicine, 2-174 Edobashi, Tsu city, Mie 514-8507, Japan.
authors.forename: Aki
authors.initials: A
authors.lastname: Fukuda
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Kusuzaki
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Hirata
authors.forename: Takao
authors.initials: T
authors.lastname: Matsubara
authors.forename: Masashi
authors.initials: M
authors.lastname: Seto
authors.forename: Akihiko
authors.initials: A
authors.lastname: Matsumine
authors.forename: Atsumasa
authors.initials: A
authors.lastname: Uchida
mesh_terms: D000368:Aged; D006801:Humans; D008297:Male; D018317:Nerve Sheath Neoplasms / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology / Q000556:secondary*; D012983:Soft Tissue Neoplasms / Q000601:surgery*; D013524:Surgical Flaps / Q000473:pathology*