Flaccid quadriplegia due to necrotizing myopathy following lung transplantation.
Critical illness myopathy (CIM) which is common after sepsis and multiorgan failure also has been described after organ transplantation. Prior reports of CIM after lung transplantation have not recorded a necrotizing myopathy. We present a 42-year-old man who developed a necrotizing critical illness myopathy following bilateral orthotopic lung transplantation. In addition we provide pathological confirmation that the ventral roots, spinal cord and the rest of the neuraxis are preserved in this condition. Extensive muscle necrosis is documented.
Maramattom
B
B
Department of Neurology, Mayo Clinic, Rochester, Minnesota 55902, USA.
Wijdicks
E F M
EF
Sundt
T M
TM
Cassivi
S D
SD
D000328:Adult; D001344:Autopsy; D017809:Fatal Outcome; D006801:Humans; D006976:Hypertension, Pulmonary / Q000601:surgery*; D016040:Lung Transplantation / Q000009:adverse effects*; D008297:Male; D018482:Muscle, Skeletal / Q000473:pathology; D009135:Muscular Diseases / Q000473:pathology*; D009336:Necrosis; D011782:Quadriplegia / Q000209:etiology / Q000473:pathology*