title: [Update on treatment of bladder cancer].
abstract: The main objective of this review is to present various types of treatment which are available for patients with bladder cancer. Some treatments are standard and some are being tested in clinical trials. Nowadays we have a lot of new treatment approaches and can use them for bladder cancer treatment. For superficial bladder cancer the main treatment method is operation. Adjuvant chemotherapy is indicated only for high-risk patients and the tumor recurrence rate is decreased to about 20%. Surgery and radiotherapy is used for muscle-invasive bladder cancer. There are no clear indications for neoadjuvant treatment administration. Radiotherapy and chemotherapy are suitable after no radical operation. Administration of palliative chemotherapy for metastatic disease might improve survival. We have to use different methods of treatment (operation, chemotherapy, radiotherapy, biology therapy) as multimodality treatment option for bladder cancer.
authors.affiliation: Clinic of Oncology, Kaunas University of Medicine, Lithuania. visocram@yahoo.com
authors.forename: Ramūne
authors.initials: R
authors.lastname: Visockiene
authors.forename: Artūras
authors.initials: A
authors.lastname: Inciūra
authors.forename: Elona
authors.initials: E
authors.lastname: Juozaityte
mesh_terms: D020533:Angiogenesis Inhibitors / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D015653:Cystectomy / Q000379:methods; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D010166:Palliative Care; D011300:Preoperative Care; D011379:Prognosis; D011879:Radiotherapy Dosage; D018714:Radiotherapy, Adjuvant; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D013997:Time Factors; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*
chemical_list: D020533:Angiogenesis Inhibitors; D000911:Antibodies, Monoclonal; D007155:Immunologic Factors