[Observation of antibody screen of patients with autoimmune hemolytic anemia].
To observe of alloantibodies of patients with autoimmune hemolytic anemia (AIHA), the alloantibodies masked by autoiantibody were detected by using chloroquine elution test, and the specificity of autoantibody was identified by ether elution test. The results showed that 19 cases out of 38 patients with AIHA were positive detected by indirect antiglobulin test and in 7 cases of them alloantibodies in sera cases were found (1 case of anti-D, 4 cases of anti-E and 2 cases of anti-CE), in 5 cases of them alloantibody were detected carried blood group specificity (3 cases of anti-E, anti-C and anti-c 1 case respectively). In conclusion, detections of alloantibodies by chloroquine elution test and ether elution test were very important for transfusion safety in therapy of patients with AIHA.
Yang
Shao-Ming
SM
Shaoguan Blood Center, Shaoguan 512026, China.
Lan
Jiong-Cai
JC
Hu
Li-Ya
LY
Lou
Hong-Qing
HQ
D000017:ABO Blood-Group System; D000293:Adolescent; D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000276:immunology*; D001323:Autoantibodies / Q000097:blood*; D001788:Blood Grouping and Crossmatching / Q000379:methods; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D006801:Humans; D007518:Isoantibodies / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012204:Rh-Hr Blood-Group System
D000017:ABO Blood-Group System; D001323:Autoantibodies; D007518:Isoantibodies; D012204:Rh-Hr Blood-Group System