title: Proliferative activity of chosen central nervous system (CNS) neoplasms.
abstract: Gliomas are the most common neoplastic tumours of the central nervous system. The aim of the study was to evaluate the proliferative activity of chosen types of gliomas and to analyse their correlation with histological type, malignancy grade, location, size and clinical symptoms. The study involved patients with astrocytoma, anaplastic astrocytoma, glioblastoma, oligodendroglioma, anaplastic oligodendroglioma. The proliferative activity (the labelling index--LI) of glial cells was estimated, using immunohistochemistry. In studied groups, a positive correlation was noted between the proliferative activity and tumour size, but not between the proliferative activity and tumour location. The clinical symptoms were conditioned mainly by tumour location and, to a smaller extent, by its size.
authors.affiliation: Department of Human Anatomy, Medical University of Białystok, Poland.
authors.forename: A
authors.initials: A
authors.lastname: Lebelt
authors.forename: M
authors.initials: M
authors.lastname: Szkudlarek
authors.forename: K
authors.initials: K
authors.lastname: Guzińska-Ustymowicz
authors.forename: D
authors.initials: D
authors.lastname: Lemancewicz
authors.forename: L
authors.initials: L
authors.lastname: Zimnoch
authors.forename: J
authors.initials: J
authors.lastname: Dziecioł
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001254:Astrocytoma / Q000473:pathology; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery; D002455:Cell Division / Q000502:physiology*; D005260:Female; D005909:Glioblastoma / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009837:Oligodendroglioma / Q000473:pathology