title: Notochord morphogenesis: a prickly subject for ascidians.
abstract: Orchestrated cell movements marshalled by proper cell polarity in the developing body axes are fundamental to the elongation of the notochord during chordate embryogenesis. A recent study shows that, in ascidians, the planar cell polarity gene prickle regulates sequential establishment of cell polarity during two phases of notochord morphogenesis.
authors.affiliation: Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK. m.tada@ucl.ac.uk
authors.forename: Masazumi
authors.initials: M
authors.lastname: Tada
mesh_terms: D000818:Animals; D019521:Body Patterning; D016764:Cell Polarity / Q000235:genetics / Q000502:physiology; D004268:DNA-Binding Proteins / Q000235:genetics; D018507:Gene Expression Regulation, Developmental; D009024:Morphogenesis; D009672:Notochord / Q000196:embryology; D010641:Phenotype; D019170:Somites / Q000502:physiology; D014561:Urochordata / Q000196:embryology
chemical_list: D004268:DNA-Binding Proteins