title: Single-stage debridement and instrumentation for pyogenic spinal infections.
abstract: Surgical intervention is indicated for pyogenic vertebral discitis and osteomyelitis in patients in whom medical therapy has failed, and in those with neurological compromise, mechanical instability, epidural abscess, or intractable pain. Surgical management has evolved to include single-stage operations for debridement and stabilization as well as more aggressive reconstruction strategies with respect to instrumentation. A review of the literature demonstrates excellent outcomes with single-stage operations and placement of hardware wherever it is required. Using this method, the authors have treated 16 patients without a single incidence of recurrent infection or hardware failure after almost 2 years of follow up.
authors.affiliation: Department of Neurological Surgery, Columbia University, New York, New York, USA.
authors.forename: Alfred T
authors.initials: AT
authors.lastname: Ogden
authors.forename: Michael G
authors.initials: MG
authors.lastname: Kaiser
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy / Q000601:surgery*; D003646:Debridement / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D013122:Spinal Diseases / Q000188:drug therapy / Q000601:surgery*
chemical_list: D000900:Anti-Bacterial Agents