title: Cytochrome P-450 under pressure: more evidence for a link between 20-hydroxyeicosatetraenoic acid and hypertension.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Fleming
mesh_terms: D019943:Amino Acid Substitution; D000818:Animals; D016718:Arachidonic Acid / Q000378:metabolism; D042926:Cytochrome P-450 CYP4A; D003577:Cytochrome P-450 Enzyme System / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D000072470:Cytochrome P450 Family 4; D005260:Female; D006801:Humans; D006893:Hydroxyeicosatetraenoic Acids / Q000096:biosynthesis / Q000502:physiology*; D006973:Hypertension / Q000201:enzymology* / Q000235:genetics / Q000503:physiopathology; D007668:Kidney / Q000201:enzymology; D007850:Lauric Acids / Q000378:metabolism; D008297:Male; D051379:Mice; D006899:Mixed Function Oxygenases / Q000172:deficiency / Q000235:genetics; D020125:Mutation, Missense; D017354:Point Mutation; D011110:Polymorphism, Genetic; D051381:Rats; D012689:Sequence Homology, Nucleic Acid; D012737:Sex Factors; D015398:Signal Transduction; D014661:Vasoconstriction / Q000502:physiology
chemical_list: C436963:Cyp4a14 protein, mouse; D006893:Hydroxyeicosatetraenoic Acids; D007850:Lauric Acids; C400322:cytochrome P-450 CYP2C subfamily; C030358:lauric acid; D016718:Arachidonic Acid; C055986:19-hydroxy-5,8,11,14-eicosatetraenoic acid; C055987:20-hydroxy-5,8,11,14-eicosatetraenoic acid; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D000072470:Cytochrome P450 Family 4; C465478:CYP4A11 protein, human; C471051:CYP4A22 protein, human; D042926:Cytochrome P-450 CYP4A