Tyrosinase-inhibitory long-chain esters from Amberboa ramosa.
Long-chain esters 1 and 2 have been isolated from the chloroform-soluble fraction of Amberboa ramosa and their structures assigned to be methyl 2beta(2S)-hydroxyl-7(E)-tritriacontenoate (1) and methyl 2beta(2S)-O-beta-D-galactopyranosyl-7(E)-tetratriacontenoate (2). In addition, tricontane (3) and apigenin (4) are also reported for the first time from this species. The structures were assigned on the basis of 1D and 2D NMR techniques. Compounds 1 and 2 showed strong to moderate inhibitory activity against tyrosinase.
Khan
Sher Bahadar
SB
International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, Pakistan.
Azhar-Ul-Haq
Afza
Nighat
N
Malik
Abdul
A
Khan
Mahmud Tariq Hasan
MT
Shah
Muhammad Raza
MR
Choudhary
Muhammad Iqbal
MI
D019659:Asteraceae; D004952:Esters; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010455:Peptides / Q000737:chemistry* / Q000302:isolation & purification*; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification
D004952:Esters; D010455:Peptides; D010936:Plant Extracts; D014442:Monophenol Monooxygenase