title: Transnitrosation of nitrosothiols: characterization of an elusive intermediate.
abstract: We report an investigation of the reaction between (S)-nitroso-l-cysteine ethyl ester and l-cysteine ethyl ester as a model of physiologically relevant transnitrosation processes. Our theoretical and experimental evidence clearly supports the existence of a nitroxyl disulfide intermediate in solution.
authors.affiliation: Departamento de Química Inorgánica, Analítica y Química Física/INQUIMAE-CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pab. II, (C1428EHA) Buenos Aires, Argentina.
authors.forename: Laura L
authors.initials: LL
authors.lastname: Perissinotti
authors.forename: Adrián G
authors.initials: AG
authors.lastname: Turjanski
authors.forename: Darío A
authors.initials: DA
authors.lastname: Estrin
authors.forename: Fabio
authors.initials: F
authors.lastname: Doctorovich
mesh_terms: D003545:Cysteine / Q000031:analogs & derivatives* / Q000737:chemistry*; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015538:Nitrosation; D009603:Nitroso Compounds / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D009603:Nitroso Compounds; C429310:S-nitrosocysteine ethyl ester; C031752:ethyl cysteine; D003545:Cysteine