title: AGML Central: web based gel proteomic infrastructure.
abstract: CONCLUSIONS
  AGML Central is a web-based open-source public infrastructure for dissemination of two-dimensional Gel Electrophoresis (2-DE) proteomics data in AGML format (Annotated Gel Markup Language). It includes a growing collection of converters from proprietary formats such as those produced by PDQUEST (BioRad), PHORETIX 2-D (Nonlinear Dynamics) and Melanie (GenBio SA). The resulting unifying AGML formatted entry, with or without the raw gel images, is optionally stored in a database for future reference. AGML Central was developed to provide a common platform for data dissemination and development of 2-DE data analysis tools. This resource responds to an increasing use of AGML for 2-DE public source data representation which requires automated tools for conversion from proprietary formats. Conversion and short-term storage is made publicly available, permanent storage requires prior registering. A JAVA applet visualizer was developed to visualize the AGML data with cross-reference links. In order to facilitate automated access a SOAP web service is also included in the AGML Central infrastructure.
  
  
  BACKGROUND
  http://bioinformatics.musc.edu/agmlcentral.
authors.affiliation: Department of Biostatistics, Bioinformatics and Epidemiology, Charleston, SC 29425, USA. stanisrc@musc.edu
authors.forename: Romesh
authors.initials: R
authors.lastname: Stanislaus
authors.forename: Chuming
authors.initials: C
authors.lastname: Chen
authors.forename: Jennifer
authors.initials: J
authors.lastname: Franklin
authors.forename: John
authors.initials: J
authors.lastname: Arthur
authors.forename: Jonas S
authors.initials: JS
authors.lastname: Almeida
mesh_terms: D003628:Database Management Systems; D030562:Databases, Protein; D015180:Electrophoresis, Gel, Two-Dimensional / Q000379:methods*; D020869:Gene Expression Profiling / Q000379:methods; D033181:Information Dissemination / Q000379:methods; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet; D020543:Proteome / Q000737:chemistry* / Q000378:metabolism*; D040901:Proteomics / Q000379:methods; D014584:User-Computer Interface
chemical_list: D020543:Proteome