title: Usefulness of C-reactive protein as an independent predictor of death in patients with ischemic cardiomyopathy.
abstract: The usefulness of serum C-reactive protein, an inflammatory marker, to predict mortality risk in patients who have ischemic cardiomyopathy was investigated. C-reactive protein was measured in 123 men who underwent cardiac catheterization and were noted to have left ventricular ejection fraction <or=45% and significant angiographic coronary artery disease. They were prospectively followed for 3 years. Higher levels of C-reactive protein were associated with increased mortality rate. This correlation was independent of other prognostic factors, such as age, ejection fraction, symptoms of severe congestive heart failure, use of angiotensin-converting enzyme inhibitors, and use of beta blockers.
authors.affiliation: Division of Cardiology, Department of Medicine, University of Miami School of Medicine and Veterans Affairs Medical Center, Miami, Florida 33125, USA.
authors.forename: Julio A
authors.initials: JA
authors.lastname: Chirinos
authors.forename: Juan P
authors.initials: JP
authors.lastname: Zambrano
authors.forename: Simon
authors.initials: S
authors.lastname: Chakko
authors.forename: Alan
authors.initials: A
authors.lastname: Schob
authors.forename: Anila
authors.initials: A
authors.lastname: Veerani
authors.forename: Guido O
authors.initials: GO
authors.lastname: Perez
authors.forename: Armando J
authors.initials: AJ
authors.lastname: Mendez
mesh_terms: D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood* / Q000401:mortality*; D011237:Predictive Value of Tests; D011379:Prognosis; D011446:Prospective Studies
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein