title: [Complete response in an elderly patient with advanced gastric cancer treated with TS-1].
abstract: The patient was an 89-year-old woman whose complaints were anorexia and weight loss. As a result of various examinations, she was diagnosed with advanced gastric cancer, Borrmann 3. TS-1 was administered at 75 mg/day for two weeks followed by one-week discontinvation during hospitalization; This course was then repeated after discharge. Anorexia and weight loss improved after two weeks, and complete response (CR) was obtained after 10 months of treatment. No cancer cells were confirmed by endoscopic biopsy. During this period no severe toxicities occurred. This TS-1 administration schedule appears to be a feasible and effective therapy for elderly patients with advanced gastric cancer.
authors.affiliation: Dept of Internal Medicine, Tenyoukai Chyuo Hospital.
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Ijuin
authors.forename: Daigo
authors.initials: D
authors.lastname: Tokitou
authors.forename: Eiichi
authors.initials: E
authors.lastname: Adachi
authors.forename: Katsuhiro
authors.initials: K
authors.lastname: Imamura
authors.forename: Shinichi
authors.initials: S
authors.lastname: Imamura
authors.forename: Takeshi
authors.initials: T
authors.lastname: Arima
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Atsuchi
authors.forename: Ko
authors.initials: K
authors.lastname: Nakano
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Kotobuki
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology; D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005260:Female; D005773:Gastroscopy; D006801:Humans; D010094:Oxonic Acid / Q000627:therapeutic use*; D011725:Pyridines / Q000627:therapeutic use*; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005641:Tegafur / Q000627:therapeutic use*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid