title: Autoimmune haemolysis as an unusual cause of anaemia in von Recklinghausen's disease.
abstract: Von Recklinghausen's disease, now classified as neurofibromatosis type 1 (NF-1), is a relatively frequent autosomal dominant disorder and has clinical manifestations, such as cafe-au-lait spots, freckling, generalised cutaneus neurofibroma, Lisch nodules, short stature, optic glioma and central nervous system tumours. In adults, anaemia in the course of NF-1 is usually due to gastrointestinal tumour bleeding. Association of NF-1 and autoimmune haemolytic anaemia is unusual. Here, we report a 48-year-old woman with NF-1 presenting as autoimmune haemolytic anaemia. We also reviewed the literature about the association of NF-1 and autoimmune diseases.
authors.affiliation: Department of Gastroenterology, Ege Universitesi Tip Fakültesi, Gastroenteroloji Bilim Dali, Bornova 35100, Izmir, Turkey. drtekinfatih@yahoo.com
authors.forename: F
authors.initials: F
authors.lastname: Tekin
authors.forename: O
authors.initials: O
authors.lastname: Ozutemiz
authors.forename: S
authors.initials: S
authors.lastname: Carcurgan
authors.forename: T
authors.initials: T
authors.lastname: Ilter
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D019080:Cafe-au-Lait Spots / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D020752:Neurocutaneous Syndromes / Q000209:etiology; D009456:Neurofibromatosis 1 / Q000175:diagnosis / Q000503:physiopathology*; D011239:Prednisolone / Q000627:therapeutic use; D012871:Skin Diseases / Q000209:etiology
chemical_list: D011239:Prednisolone