[The present and future of home care chemotherapy for patients with advanced and recurrent colorectal cancer].
OBJECTIVE
If the chemotherapy at home is as effective as the chemotherapy at an outpatient clinic, QOL of the patients will be improved. In this paper the future of chemotherapy at home was clarified from the outcome of the chemotherapy for advanced and recurrent colorectal cancer.


METHODS
Hepatic arterial infusion chemotherapy (HAI) (5-FU 2,000 mg/w, continuous infusion for 7 days, n=123) for unresectable liver metastases and FL chemotherapy (5 FU 1,500 mg + l-LV 375 mg/w, continuous systemic chemotherapy for 7 days, n=32) for extra hepatic recurrence were carried out at home by a portable pump system every other week.


RESULTS
The response rates were 61.2% in HAI and 18.8% in FL. MST were 14.7 months in HAI and 10.8 months in FL. It was important to establish a surveillance network system to continue the chemotherapy at home.


CONCLUSIONS
It was suggested that the chemotherapy at home was effective and to maintain the patient's QOL as one of the options.
Takahashi
Keiichi
K
Dept. of Surgery, Tokyo Metropolitan Komagome Hospital.
Mori
Takeo
T
Yamaguchi
Tatsuro
T
Matsumoto
Hiroshi
H
Miyamoto
Hidenori
H
Arai
Kuniyoshi
K
Iwasaki
Yoshiaki
Y
Katayanagi
Sou
S
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage; D006499:Hepatic Artery; D018718:Home Infusion Therapy / Q000639:trends*; D006801:Humans; D007261:Infusions, Intra-Arterial; D002955:Leucovorin / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000556:secondary; D011379:Prognosis; D011788:Quality of Life; D015996:Survival Rate
D002955:Leucovorin; D005472:Fluorouracil