Quality of life after macular translocation with 360 degrees peripheral retinectomy for age-related macular degeneration.
OBJECTIVE
To determine patients' quality of life (QOL) after macular translocation with 360 degrees peripheral retinectomy (MT360) for age-related macular degeneration.


METHODS
Prospective, interventional, consecutive, noncomparative case series.


METHODS
A prospective study assessed QOL 1 year after MT360 and its relation to postoperative visual function. The 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) and the Medical Outcomes Study 12-item short form (SF-12) health survey were used to assess vision-related QOL and general health, respectively. Surveys were administered preoperatively and postoperatively. Postoperative NEI VFQ-25 QOL and SF-12 subscale scores for all patients were compared with the preoperative scores. Preoperative and postoperative distance and near visual acuities (VAs) and reading speed were assessed. Changes in NEI VFQ-25 QOL subscale scores were compared in patients with and without improved visual function. Postoperative NEI VFQ-25 QOL subscale scores in patients with distance VA of >or=69 Early Treatment Diabetic Retinopathy Study letters, near VA of >or=20/70, and reading speed of >or=90 words per minute were compared with subscale scores in patients with worse postoperative visual function.


METHODS
National Eye Institute VFQ-25 and SF-12 QOL scores and their association with distance VA, near VA, and reading speed.


RESULTS
In total, 50 patients with a mean age of 76.9 years were studied. Postoperative mean NEI VFQ-25 QOL scores were higher than the preoperative mean scores, and this difference was significant for important vision-specific subscales. Patients with improved visual function had greater mean changes in NEI VFQ-25 QOL scores than those with no improvement. Patients with the outlined higher levels of visual function had greater mean NEI VFQ-25 QOL scores than those who had worse visual function. Preoperative and postoperative mean SF-12 QOL scores were similar.


CONCLUSIONS
Macular translocation with 360 degrees peripheral retinectomy was associated with improvement in vision-related QOL. The amount of improvement was greatest in patients with postoperative improvement in visual function, and the best postoperative vision-related QOL was seen in patients with better postoperative visual function. This was not associated with a change in patients' general health.
Cahill
Mark T
MT
Duke University Eye Center, Durham, North Carolina 27710, USA.
Stinnett
Sandra S
SS
Banks
Avie D
AD
Freedman
Sharon F
SF
Toth
Cynthia A
CA
D000368:Aged; D005260:Female; D006306:Health Surveys; D006801:Humans; D008268:Macular Degeneration / Q000601:surgery*; D008297:Male; D011446:Prospective Studies; D011788:Quality of Life; D011932:Reading; D012160:Retina / Q000637:transplantation*; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D014792:Visual Acuity / Q000502:physiology