Metal-enhanced fluorescence solution-based sensing platform.
In recent years our laboratories have reported the favorable effects for fluorophores placed in close proximity to surface immobilized silver nanostructures. These include; greater quantum yields, reduced lifetimes (increased photostability) and directional emission. However, while these findings are likely to find multifarious applications for surface assays based on enhanced fluorescence detection, a solution based enhanced sensing platform has yet to be realized. In this short, note, we show how SiO2-coated silver colloids, indeed provide for a solution based enhanced fluorescence sensing platform with a 3-5 fold enhancement typically observed.
Asian
Kadir
K
Institute of Fluorescence, Medical Biotechnology Center, University of Maryland Biotechnology Institute, Baltimore, Maryland, USA.
Lakowicz
Joseph R
JR
Szmacinski
Henryk
H
Geddes
Chris D
CD
D003102:Colloids; D005453:Fluorescence; D005456:Fluorescent Dyes; D008670:Metals; D049329:Nanostructures; D012822:Silicon Dioxide; D012834:Silver; D012996:Solutions; D013499:Surface Properties
D003102:Colloids; D005456:Fluorescent Dyes; D008670:Metals; D012996:Solutions; D012834:Silver; D012822:Silicon Dioxide