[Galectin-3 in differential diagnosis and prognosis of follicular tumors of the thyroid gland].
Differential diagnosis between follicular thyroid tumours (FTT) is difficult both at cytological and histological levels. Infiltrative growth is authentic criterion of malignancy. Immunohistochemical reaction (PAP-method) with galectin-3 antibodies was used. The results allow to make differential diagnosis of thyroid tumours before the surgery. Immunohistochemical identification of galectin-3 in the tissue of follicular adenomas with grave dysplasia and follicular carcinoma is an unfavourable prognostic sign.
Iushkov
P V
PV
Antonova
S S
SS
Bartolazzi
A
A
D018263:Adenocarcinoma, Follicular / Q000378:metabolism / Q000473:pathology*; D044963:Biopsy, Fine-Needle; D003937:Diagnosis, Differential; D037502:Galectin 3 / Q000378:metabolism*; D006801:Humans; D011379:Prognosis; D013961:Thyroid Gland / Q000378:metabolism / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000378:metabolism / Q000473:pathology*
D037502:Galectin 3