title: ProtTest: selection of best-fit models of protein evolution.
abstract: CONCLUSIONS
  Using an appropriate model of amino acid replacement is very important for the study of protein evolution and phylogenetic inference. We have built a tool for the selection of the best-fit model of evolution, among a set of candidate models, for a given protein sequence alignment.
  
  
  BACKGROUND
  ProtTest is available under the GNU license from http://darwin.uvigo.es
authors.affiliation: Department of Biochemistry, Genetics and Immunology, Universidad de Vigo, Spain. fabascal@uvigo.es
authors.forename: Federico
authors.initials: F
authors.lastname: Abascal
authors.forename: Rafael
authors.initials: R
authors.lastname: Zardoya
authors.forename: David
authors.initials: D
authors.lastname: Posada
mesh_terms: D000465:Algorithms; D000595:Amino Acid Sequence; D019943:Amino Acid Substitution / Q000235:genetics; D000596:Amino Acids / Q000737:chemistry* / Q000235:genetics*; D003196:Computer Graphics; D003198:Computer Simulation; D004252:DNA Mutational Analysis / Q000379:methods; D019143:Evolution, Molecular; D006801:Humans; D020407:Internet; D008957:Models, Genetic; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed / Q000235:genetics; D010802:Phylogeny; D011506:Proteins / Q000737:chemistry* / Q000235:genetics*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software; D013329:Structure-Activity Relationship; D014584:User-Computer Interface
chemical_list: D000596:Amino Acids; D011506:Proteins