title: Immunolocalization of VR1 and VRL1 in rat larynx.
abstract: Immunoreactivity for vanilloid receptor subtype 1 (VR1) and its analogue vanilloid receptor-like protein 1 (VRL1) were examined in combination with immunoreactivity for substance P (SP) and calcitonin gene-related peptide (CGRP) in the rat larynx. VR1 and VRL1 immunoreactivity were observed in the intraepithelial free nerve endings, subepithelial nerve plexus and laryngeal epithelial cells. Most of VR1 immunoreactive nerves were also immunoreactive for SP or CGRP. VR1 immunoreactive intraepithelial nerve endings may be laryngeal nociceptors.
authors.affiliation: Laboratory of Veterinary Anatomy, Department of Veterinary Sciences, Faculty of Agriculture, Iwate University, Ueda 3-19-8, Morioka, Iwate, 080-8550, Japan. yyoshio@iwate-u.ac.jp
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Taniguchi
mesh_terms: D000818:Animals; D015740:Calcitonin Gene-Related Peptide; D007150:Immunohistochemistry / Q000379:methods; D007473:Ion Channels / Q000378:metabolism*; D007830:Larynx / Q000378:metabolism*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D011955:Receptors, Drug / Q000378:metabolism*; D013373:Substance P / Q000378:metabolism; D050916:TRPV Cation Channels
chemical_list: D007473:Ion Channels; D011955:Receptors, Drug; D050916:TRPV Cation Channels; C493922:Trpv1 protein, rat; C476722:Trpv2 protein, rat; D013373:Substance P; D015740:Calcitonin Gene-Related Peptide