title: [Stimulation of labour with premature rupture of membranes].
abstract: BACKGROUND
  The objective is to examine the efficiency of the application of prostaglandins (PgE2) in labours with the complications of premature rupture of membranes (PRM) for the purpose of their more frequent use.
  
  
  METHODS
  Two groups of term labours with the complications of PRM were observed in Gynaecology and Obstetric Clinic in Tuzla, in 2002. In the examination group No=59 (46.82%), we used vaginal suppositories prostin E2 (3 mg) for stimulation of labour. In the second group of pregnant women, No=67 (53.17%) we used oxytocin for stimulation. The following was observed: the age of pregnant women, parity, Bishop score, latent period (time from application of the medicine until delivery), manner in which the labour was ended, birth weight, Apgar score after the first and the fifth minute, incidence of complications (infections and bleeding) in the period of confinement/puerperium).
  
  
  RESULTS
  PgE2 were applied in pregnancies in earlier gesational age (37.31 versus 39.13), more often in nulliparous women (86.46%), in the case of immature cervix (Bishop score 3.70 versus 5.95). There were 80.45% successful stimulation, the same incidence of Cesarean sections, with no difference in the condition of newborns at birth (average Apgar score in the group with Pg 8.63), without difference in the incidence of complications in the confinement puerperium. In the group with Pg, there was a small percentage of infections, although the latent period was in 5.67% pregnancies longer than 24 hours.
  
  
  CONCLUSIONS
  The application of PgE2 vaginal suppositories for maturing and stimulation of labour is a modern, efficient and easy to use method in obstetrics which is very acceptable.
authors.affiliation: Ginekolosko-akuserska klinika, Univerzitetski klinicki centar Tuzla, Trnovac.
authors.forename: Gordana
authors.initials: G
authors.lastname: Bogdanović
authors.forename: Gordana
authors.initials: G
authors.lastname: Grgić
mesh_terms: D015232:Dinoprostone / Q000008:administration & dosage; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D007751:Labor, Induced / Q000379:methods*; D010120:Oxytocics / Q000008:administration & dosage; D011247:Pregnancy; D013488:Suppositories
chemical_list: D010120:Oxytocics; D013488:Suppositories; D015232:Dinoprostone