title: Intermediate filament networks: in vitro and in vivo assembly models.
abstract: We propose two systems of ordinary differential equations modeling the assembly of intermediate filament networks. The first one describes the in vitro intermediate filament assembly dynamics. The second one deals with the in vivo evolution of cytokeratin, which is the intermediate filament protein expressed by epithelial cells. The in vitro model is then briefly analyzed in a simplified case.
authors.affiliation: The Samuel Lunenfeld Research Institute, Room 1060, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, Canada. sportet@mshri.on.ca
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Portet
authors.forename: Jany
authors.initials: J
authors.lastname: Vassy
authors.forename: Christopher W V
authors.initials: CW
authors.lastname: Hogue
authors.forename: Julien
authors.initials: J
authors.lastname: Arino
authors.forename: Ovide
authors.initials: O
authors.lastname: Arino
mesh_terms: D000818:Animals; D007382:Intermediate Filaments / Q000502:physiology* / Q000648:ultrastructure*; D007633:Keratins / Q000502:physiology; D008954:Models, Biological
chemical_list: D007633:Keratins