title: Spatially encoded NMR and the acquisition of 2D magnetic resonance images within a single scan.
abstract: An approach that enables the acquisition of multidimensional NMR spectra within a single scan has been recently proposed and demonstrated. The present paper explores the applicability of such ultrafast acquisition schemes toward the collection of two-dimensional magnetic resonance imaging (2D MRI) data. It is shown that ideas enabling the application of these spatially encoded schemes within a spectroscopic setting, can be extended in a straightforward manner to pure imaging. Furthermore, the reliance of the original scheme on a spatial encoding and subsequent decoding of the evolution frequencies endows imaging applications with a greater simplicity and flexibility than their spectroscopic counterparts. The new methodology also offers the possibility of implementing the single-scan acquisition of 2D MRI images using sinusoidal gradients, without having to resort to subsequent interpolation procedures or non-linear sampling of the data. Theoretical derivations on the operational principles and imaging characteristics of a number of sequences based on these ideas are derived, and experimentally validated with a series of 2D MRI results collected on a variety of model phantom samples.
authors.affiliation: Department of Chemical Physics, Weizmann Institute of Science, 76100 Rehovot, Israel.
authors.forename: Yoav
authors.initials: Y
authors.lastname: Shrot
authors.forename: Lucio
authors.initials: L
authors.lastname: Frydman
mesh_terms: D000465:Algorithms; D017352:Echo-Planar Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D019047:Phantoms, Imaging; D012815:Signal Processing, Computer-Assisted