title: Gender differences in electroconvulsive therapy: a retrospective chart review.
abstract: BACKGROUND
  There is a growing interest in gender differences of different psychiatric disorders, especially major depression. We sought a possible gender difference related to electroconvulsive therapy (ECT).
  
  
  METHODS
  This retrospective study compared 20 male and 23 female depressed adult patients treated by ECT. We compared their findings on gender differences to those of 12 female and 4 male bipolar patients and 11 male and 19 female schizophrenic patients, all treated in the same ECT setting.
  
  
  RESULTS
  Depressed female patients underwent significantly fewer antidepressant drug trials than males before being referred to ECT (t41=2.09, P<0.05). A similar gender difference was found in the treatment of patients suffering from schizophrenia: female patients underwent fewer pharmacological antipsychotic trials than males before being referred to ECT (t28=3.11, P<0.01). ECT was significantly more effective in female patients than in male patients suffering from schizophrenia (U=38, P<0.05).
  
  
  CONCLUSIONS
  This is a retrospective pilot study whose results are based on subjective evaluations.
  
  
  CONCLUSIONS
  The findings of this study may support a gender difference both in referral and in the outcome of ECT.
  
  
  CONCLUSIONS
  there might be a need to consider lowering the number of pre-ECT drug trials for depressed males and to consider ECT as a viable therapeutic option for schizophrenic females.
authors.affiliation: Shalvata Mental Health Center, Hod Hasharon, P.O. Box 94, Israel, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. blochy@netvision.net.il
authors.forename: Yuval
authors.initials: Y
authors.lastname: Bloch
authors.forename: Gideon
authors.initials: G
authors.lastname: Ratzoni
authors.forename: Doli
authors.initials: D
authors.lastname: Sobol
authors.forename: Shlomo
authors.initials: S
authors.lastname: Mendlovic
authors.forename: Gilad
authors.initials: G
authors.lastname: Gal
authors.forename: Yechiel
authors.initials: Y
authors.lastname: Levkovitz
mesh_terms: D003865:Major Depressive Disorder / Q000628:therapy*; D004565:Electroconvulsive Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012737:Sex Factors