[Measurement of uric acid of seminal plasma in fertile and infertile males].
OBJECTIVE
To measure uric acid of seminal plasma in fertile and infertile males.


METHODS
One hundred and sixty-three infertile males were divided into an obstructive azoospermic group (15 cases), a non-obstructive azoospermic group (36 cases), an oligozoospermic group (43 cases), and an asthenozoospermic group (69 cases). Twenty fertile males were included in the control group. Uric acid concentrations of seminal plasma in the fertile and infertile men were assessed by spectrophotometer, and sperm parameters were analyzed by computer-assisted semen analysis (CASA) system.


RESULTS
Uric acid concentration of seminal plasma in the control group was significantly higher than all the infertile groups (P < 0.01), and that of the obstructive azoospermic group significantly lower than the other infertile groups (P < 0.1), but no significant difference was observed among the other infertile groups (P > 0.05).


CONCLUSIONS
Uric acid may play an important role in male reproduction because of its antioxidative property.
Xu
Kaisheng
K
Laboratory of Reproduction & Genetics, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.
Shang
Xuejun
X
Chen
Yonggang
Y
Zhao
Feng
F
Zhu
Peiyuan
P
Huang
Yufeng
Y
D000328:Adult; D053713:Azoospermia / Q000378:metabolism; D016022:Case-Control Studies; D006801:Humans; D007248:Infertility, Male / Q000378:metabolism*; D008297:Male; D009845:Oligospermia / Q000378:metabolism; D012661:Semen / Q000737:chemistry*; D014527:Uric Acid / Q000032:analysis*
D014527:Uric Acid