[Botulinum toxin A in the treatment of congenital nystagmus in children].
OBJECTIVE
To evaluate the use of, botulinum toxin A in the treatment of congenital nystagmus in children.


METHODS
32 children with nystagmus and esotropia (group I), nystagmus and exotropia (group II) and horizontal and vertical nystagmus (group III). Intramuscular injections of botulinum toxin A was performed in all treated children.


RESULTS
In group I the amplitude of nystagmus diminished of 50%, in group II of 42.9% and in group III of 28,6%. Near and distant visual acuity improved in all treated children.


CONCLUSIONS
Treatment of congenital nystagmus with botulinum toxin A causes reduction of the amplitude of nystagmus, partial improvement of visual acuity and improvement of anomalous head posture.
Oleszczyńska-Prost
Ewa
E
Z Centrum Okulistyki Dzieciecej w Warszawie.
D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D004948:Esotropia / Q000601:surgery; D006801:Humans; D007223:Infant; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D020417:Nystagmus, Congenital / Q000188:drug therapy* / Q000503:physiopathology; D014792:Visual Acuity / Q000502:physiology
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A