title: New fatty acid esters originate during storage by the interaction of components in prasaplai, a Thai traditional medicine.
abstract: Prasaplai is a Thai traditional preparation composed of twelve ingredients; during storage three newly emerging compounds were detected by HPLC. Their structures were established as the new (E)-4-(3,4-dimethoxyphenyl)but-3-en-1-yl linoleate, (E)-4-(3,4-dimethoxyphenyl)but-3-en-1-yl oleate and the known (E)-4-(3,4-dimethoxyphenyl)but-3-en-1-yl palmitate on the basis of spectral data and chemical evidence. The artificial esters were already observable after one day of storage of the freshly prepared dry mixture, and steadily increased during a storage period of 30 days and more. A systematic search indicated that the three esters arose from the interaction of compounds contained in the rhizomes of Zingiber cassumunar and the seeds of Nigella sativa.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
authors.forename: Somsak
authors.initials: S
authors.lastname: Nualkaew
authors.forename: Wandee
authors.initials: W
authors.lastname: Gritsanapan
authors.forename: Frank
authors.initials: F
authors.lastname: Petereit
authors.forename: Adolf
authors.initials: A
authors.lastname: Nahrstedt
mesh_terms: D004347:Drug Interactions; D004356:Drug Storage; D006801:Humans; D008519:Medicine, Traditional; D031881:Nigella sativa; D009829:Oleic Acids / Q000737:chemistry; D008517:Phytotherapy; D018514:Plant Structures / Q000737:chemistry; D027343:Rhizome; D012639:Seeds; D013785:Thailand; D030521:Zingiberaceae
chemical_list: D009829:Oleic Acids