title: Catalytic asymmetric arylative cyclization of alkynals: phosphine-free rhodium/diene complexes as efficient catalysts.
abstract: Catalytic arylative cyclization of alkynals has been developed by the use of phosphine-free rhodium/diene complexes as catalysts. An asymmetric variant of this process has been successfully realized by employing a C2-symmetric chiral bicyclo[2.2.2]octadiene ligand. The rhodium/diene catalyst system is also effective for arylative cyclization of other substrates such as alkynones and enynes, achieving multiple carbon-carbon bond formations in a single step.
authors.affiliation: Department of Chemistry, Graduate School of Scienece, Kyoto University, Sakyo, Kyoto 606-8502, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Shintani
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Okamoto
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Otomaru
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Ueyama
authors.forename: Tamio
authors.initials: T
authors.lastname: Hayashi