[Keratolimbal allografts and multilayer amniotic membrane transplantation in the treatment of ocular surface disease due to chemical burns].
OBJECTIVE
To analyze the functional effect and to present the technique of keratolimbal allograft and multilayer amniotic membranetransplantation for the treatment of ocular surface disease after heavy chemical burn.


METHODS
Treatment comprised 3 eyes of 2 patients suffering form ocular surface deficiency after chemical (acid) burn. Surgeries were provided under local anesthesia. After circumferential peritomy and removal of fibrovascular layer, stem cells in the fashion of keratolimball crescent allograft, following by multilayer amniotic membrane transplantation were performed.


RESULTS
3 months after surgery the corneal surface was covered with fully differentiated epithelium in all patients. In two of three patients, improvement of the visual acuity was also observed. However, in one eye despite good epithelium maintenance the stroma was still not transparent.


CONCLUSIONS
Keratolimbal allograft with multilayer amniotic transplantation is interesting method of ocular surface reconstruction. Combined procedure with use of two different tissues seems to be relevant among patients with bilateral ocular surface dysfunction with complete destruction of stem cells after chemical burn.
Jurowski
Piotr
P
Z Kliniki Okulistyki i Rehabilitacji Wzrokowej Uniwersyteckiego Szpitala Klinicznego nr 2 im. WAM Uniwersytetu Medycznego w Lodzi.
Goś
Iroman
I
D000650:Amnion / Q000033:anatomy & histology* / Q000166:cytology / Q000637:transplantation*; D002057:Burns, Chemical / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D003315:Cornea / Q000601:surgery*; D016039:Corneal Transplantation / Q000379:methods*; D004847:Epithelial Cells / Q000166:cytology / Q000637:transplantation; D005126:Eye Burns / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D013508:Ophthalmologic Surgical Procedures / Q000379:methods; D019651:Plastic Surgery Procedures / Q000379:methods; D012720:Severity of Illness Index; D014184:Transplantation, Homologous