title: Ocular manifestations in Dengue fever.
abstract: OBJECTIVE
  To report a case of Dengue fever resulting in permanent visual loss in both eyes due to retinal capillary occlusion.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  Severe permanent visual loss occurred in a patient with Dengue fever. Dilated fundus exam showed vascular sheathing with associated retinal hemorrhages at the equator and cotton wool spots in the maculae of both eyes. Fluorescein angiography revealed areas of capillary nonperfusion at the equator and in the macula. The diagnosis of Dengue fever was confirmed by serology detecting IgM antibodies to the Dengue virus.
  
  
  CONCLUSIONS
  Ocular abnormalities may be seen in patients with Dengue fever, therefore ophthalmoscopy should be performed in patients presenting with severe forms of the disease.
authors.affiliation: CERV, Retina, Belo Horizonte, MG, Brazil. rubenssiqueira@terra.com.br
authors.forename: Rubens Camargo
authors.initials: RC
authors.lastname: Siqueira
authors.forename: Newton Pena
authors.initials: NP
authors.lastname: Vitral
authors.forename: Wesley Ribeiro
authors.initials: WR
authors.lastname: Campos
authors.forename: Fernando
authors.initials: F
authors.lastname: Oréfice
authors.forename: Luis Tadeu
authors.initials: LT
authors.lastname: de Moraes Figueiredo
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D001241:Aspirin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003715:Dengue / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D003716:Dengue Virus / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D015828:Eye Infections, Viral / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D017075:Laser Coagulation; D008279:Magnetic Resonance Imaging; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D012166:Retinal Hemorrhage / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D031300:Retinal Vasculitis / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D014786:Vision Disorders / Q000175:diagnosis / Q000628:therapy / Q000821:virology; D014821:Vitrectomy
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M; D010975:Platelet Aggregation Inhibitors; D001241:Aspirin