title: Surgical treatment of tracheoesophageal fistula in a patient with severe acute respiratory syndrome complicated with extensive pulmonary fibrosis.
abstract: Tracheoesophageal fistula is an uncommon complication usually associated with chronic usage of ventilator and pressure necrosis of the tracheoesophageal wall. A 56-year-old female patient with severe acute respiratory syndrome (SARS) with tracheoesophageal fistula is reported. She was intubated for ventilatory support 3 days after admission because of progressive respiratory distress. Methylprednisolone pulse therapy followed by a maintenance dosage was given due to persistence of bilateral pulmonary fibrosis. Thirty three days after admission, she underwent tracheostomy because of difficulty in weaning from the ventilator. Ten days after tracheostomy, she developed tracheoesophageal fistula, which was confirmed by bronchoscopy and panendoscopy. Tracheal resection and primary repair for the esophageal defect was performed via a cervical incision combined with partial sternotomy. She was weaned from the ventilator soon after the surgery and discharged 34 days after the operation. In SARS patients with persistent pulmonary fibrosis and under prolonged corticosteroid treatment, special care should be given to avoid intubation-related tracheal injury during the period of ventilatory support. The tracheoesophageal fistula, once developed, can be repaired in a single stage after improvement of the nutritional status.
authors.affiliation: Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Jang-Ming
authors.initials: JM
authors.lastname: Lee
authors.forename: Pei-Lin
authors.initials: PL
authors.lastname: Lee
authors.forename: Shuenn-Wen
authors.initials: SW
authors.lastname: Kuo
authors.forename: Juey-Jen
authors.initials: JJ
authors.lastname: Hwang
authors.forename: Yung-Chie
authors.initials: YC
authors.lastname: Lee
mesh_terms: D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal / Q000009:adverse effects; D008875:Middle Aged; D011658:Pulmonary Fibrosis / Q000150:complications*; D012121:Respiration, Artificial / Q000009:adverse effects; D045169:Severe Acute Respiratory Syndrome / Q000150:complications*; D014138:Tracheoesophageal Fistula / Q000209:etiology / Q000601:surgery*