[Modulation of immune system cells by lactobacilli].
The influence of lactobacilli on the proliferative potential of immune system cells after the intragastral administration of viable microbial cells and their native filtrates to mice CBA is evaluated. The data have been obtained on the modulating influence of lactobacilli on the formation of T- and B-cell immune response--their role in maintaining homeostatsis and specific features of cell mediated immune reactions after the intragastral administration of virulent Shigella dysenteriae for modeling experimental infection in CBA mice. The mechanisms of the immunomodulating action of lactobacilli on local and systemic reactions of the host as well as realization of the protective properties of lactobacilli against the causative agents of acute enteric infections are discussed.
Zorina
V V
VV
Nikolaeva
T N
TN
Bondarenko
V M
VM
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology; D002455:Cell Division; D019610:Cytoprotection; D004195:Disease Models, Animal; D004405:Dysentery, Bacillary / Q000276:immunology / Q000517:prevention & control; D007111:Immunity, Cellular; D007778:Lactobacillus / Q000276:immunology*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D010581:Peyer's Patches / Q000276:immunology; D012762:Shigella dysenteriae; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology