title: Is haplogroup X present in extant South American Indians?
abstract: A total of 1,159 mitochondrial DNA samples from two Mongolian, two Siberian, and 25 South Native American populations was surveyed for the presence of the C16278T mutation, frequently found in haplogroup X. Material from 25 carriers of that mutation was then sequenced for the hypervariable segment I (HVS-I) control region, and those that still were not classifiable in classical Amerindian haplogroups were further studied. The tests involved all the control region, as well as the presence of characteristic mutations in seven coding fragments, totalling 5,760 base pairs. The results indicate that haplogroup X is not present in these samples.
authors.affiliation: Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, 91501-970 Porto Alegre, Rio Grande do Sul, Brazil.
authors.forename: Cláudia L
authors.initials: CL
authors.lastname: Dornelles
authors.forename: Sandro L
authors.initials: SL
authors.lastname: Bonatto
authors.forename: Loreta B
authors.initials: LB
authors.lastname: De Freitas
authors.forename: Francisco M
authors.initials: FM
authors.lastname: Salzano
mesh_terms: D004272:DNA, Mitochondrial / Q000235:genetics; D005828:Genetics, Population; D006239:Haplotypes / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D007199:Indians, South American / Q000235:genetics*; D009154:Mutation / Q000235:genetics*; D010802:Phylogeny
chemical_list: D004272:DNA, Mitochondrial