Gastrointestinal neuroendocrinology.
There exists individual enteroendocrine cells spread throughout the gastrointestinal mucosa that release specific peptide, as well as nonpeptide, hormones to have various endocrine action on target cells bearing cell surface receptors selectively sensitive to these regulatory substances. Following receptor activation, a series of events is set into motion that serves to transduce the information imparted to the target cell. Such transduction mechanisms are numerous, and may be excitatory or inhibitory to the cell depending upon which G-protein subunits the receptor is coupled.
Schneider
David A
DA
Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, College of Veterinary Medicine, Wegner Hall, Room 205, Washington State University, Pullman, WA 99164-6520, USA. das@vetmed.wsu.edu
Sayegh
Ayman I
AI
D000818:Animals; D019858:Enteroendocrine Cells / Q000378:metabolism*; D041981:Gastrointestinal Tract / Q000502:physiology*; D006736:Horses / Q000502:physiology*; D007413:Intestinal Mucosa / Q000378:metabolism; D009490:Neurosecretory Systems / Q000502:physiology*; D018160:Receptors, Cytoplasmic and Nuclear / Q000378:metabolism*; D015398:Signal Transduction
D018160:Receptors, Cytoplasmic and Nuclear