title: Retinal blood flow analysis using intraoperative video fluorescein angiography combined with optical fiber-free intravitreal surgery system.
abstract: OBJECTIVE
  To report a new method to perform intraoperative video fluorescein angiography (VFA) using an optical fiber-free intravitreal surgery system (OFFISS) and retinal blood flow analysis during surgery.
  
  
  METHODS
  Observational case series.
  
  
  METHODS
  Four eyes of four patients with macular edema as a result of branch retinal vein occlusion underwent vitrectomy and intraoperative VFA with a bolus of 0.8 ml fluorescein dye. The segmental blood flow was calculated using dye dilution technique. Intraocular pressure was maintained at 15 mm Hg.
  
  
  RESULTS
  The VFA was clearly recorded with stable excitation light and very little eye movement under retrobulbar anesthesia. The segmental blood flow of the affected vessels (6.1 +/- 1.2 pixel(2)/s) was significantly lower than that of the healthy vessels (17.9 +/- 7.9 pixel(2)/s) (P < .05).
  
  
  CONCLUSIONS
  The combination of VFA and OFFISS can facilitate intraoperative VFA, and may be useful for evaluating retinal blood flow during surgery.
authors.affiliation: Department of Ophthalmology, Fujita Health University School of Medicine, Aichi, Japan. naoichi@fujita-hu.ac.jp
authors.forename: Naoichi
authors.initials: N
authors.lastname: Horio
authors.forename: Masayuki
authors.initials: M
authors.lastname: Horiguchi
mesh_terms: D000368:Aged; D001783:Blood Flow Velocity; D002386:Cataract / Q000150:complications / Q000503:physiopathology / Q000628:therapy; D005451:Fluorescein Angiography / Q000379:methods*; D006801:Humans; D007429:Intraocular Pressure; D007432:Intraoperative Period; D008269:Macular Edema / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D008875:Middle Aged; D018918:Phacoemulsification; D012039:Regional Blood Flow; D012170:Retinal Vein Occlusion / Q000150:complications / Q000503:physiopathology / Q000601:surgery; D012171:Retinal Vessels / Q000502:physiology*; D014741:Video Recording; D014821:Vitrectomy