Epstein-Barr virus-associated hemophagocytic syndrome in a patient with lupus nephritis.
Hemophagocytic syndrome (HPS) is an unusual but severe illness associated with a variety of infections, as well as genetic, malignant tumors, and autoimmune diseases. We report an 11-year-old girl with systemic lupus erythematosus and nephritis who developed HPS associated with Epstein-Barr virus reactivation. In our patient, the onset of reactive HPS might be related to immunosuppressive treatment during the course of lupus nephritis.
Isome
Masato
M
Department of Pediatrics, Fukushima Medical University School of Medicine, 1-Hikarigaoka, 960-1295 Fukushima City, Fukushima, Japan. i-masato@fmu.ac.jp
Suzuki
Junzo
J
Takahashi
Ai
A
Murai
Hiromichi
H
Nozawa
Ruriko
R
Suzuki
Shigeo
S
Kawasaki
Yukihiko
Y
Suzuki
Hitoshi
H
D002648:Child; D020031:Epstein-Barr Virus Infections / Q000139:chemically induced* / Q000821:virology; D005260:Female; D004854:Herpesvirus 4, Human; D015616:Histiocytosis, Non-Langerhans-Cell / Q000821:virology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D008181:Lupus Nephritis / Q000188:drug therapy*; D012008:Recurrence
D007166:Immunosuppressive Agents