title: Coinfection: Helicobacter pylori/human immunodeficiency virus.
abstract: To compare H. pylori infection prevalence and gastric mucosa damage in HIV-infected and non-HIV-infected patients, gastric biopsies were systematically taken in 209 individuals who underwent upper Gl endoscopy (102 HIV-infected and 107 non-HIV-infected). H. pylori was found in 42 (41.1%) HIV-infected patients and in 53 (49.5%) non-HIV patients (P = 0.22, chi2 = 1.47, NS). In HIV-positive patients infected with H. pylori the mean CD4 count was higher than in HIV-positive patients without H. pylori (364 and 228 cells/mm3, respectively; P = 0.0001). H. pylori gastritis was more severe in the HIV-positive group (chi2 = 15.02, P = 0.0001). The frequency of H. pylori in gastric mucosa in HIV-infected and non-HIV patients was similar. HIV-infected patients with H. pylori had a higher mean CD4 count than HIV-infected individuals without H. pylori. Gastric lesions associated with H. pylori were more severe in the HIV-positive population.
authors.affiliation: Hospital Fernández, Buenos Aires, Argentina. molmos@fibertel.com.ar
authors.forename: Martin
authors.initials: M
authors.lastname: Olmos
authors.forename: Valentina
authors.initials: V
authors.lastname: Araya
authors.forename: Eduardo
authors.initials: E
authors.lastname: Pskorz
authors.forename: Eduardo Coronado
authors.initials: EC
authors.lastname: Quesada
authors.forename: Hugo
authors.initials: H
authors.lastname: Concetti
authors.forename: Hector
authors.initials: H
authors.lastname: Perez
authors.forename: Pedro
authors.initials: P
authors.lastname: Cahn
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology; D000328:Adult; D018791:CD4 Lymphocyte Count; D003430:Cross-Sectional Studies; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology; D015658:HIV Infections / Q000150:complications* / Q000473:pathology; D016481:Helicobacter Infections / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D008297:Male; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D019562:Viral Load