title: Ultrasound antenatal diagnosis of cleft palate by a new technique: the 3D "reverse face" view.
abstract: OBJECTIVE
  To assess the clinical value of a novel three-dimensional (3D) ultrasound technique, the reverse face view (3D RF view), in the antenatal categorization of facial clefting and in particular clefting of the hard palate.
  
  
  METHODS
  Eight cases of suspected orofacial clefting were examined by 3D surface rendering. The fetal lips and alveolar ridge were examined in the frontal plane and the face was then rotated through 180 degrees on the vertical axis to examine the secondary palate by the 3D RF view.
  
  
  RESULTS
  In each case described, we were able to visualize the fetal face, lips and palate and make an antenatal diagnosis as to whether the palate was affected. In all cases, the antenatal diagnosis was subsequently confirmed. In one case with a left-sided cleft in the lips and alveolar ridge and an intact hard palate, the correct diagnosis was made but a cleft in the soft palate was missed.
  
  
  CONCLUSIONS
  Although clefts of the lips and alveolar ridge are readily diagnosed on high-quality antenatal ultrasound, visualization of the fetal palate using existing techniques is unreliable. In the patients described here, the 3D RF technique allowed relatively straightforward assessment of the fetal palate with a high degree of accuracy.
authors.affiliation: Create Health Clinic, 103-105 Harley Street, Imperial College, London W1G 6AJ, UK. info@createhealth.org
authors.forename: S
authors.initials: S
authors.lastname: Campbell
authors.forename: C
authors.initials: C
authors.lastname: Lees
authors.forename: G
authors.initials: G
authors.lastname: Moscoso
authors.forename: P
authors.initials: P
authors.lastname: Hall
mesh_terms: D002971:Cleft Lip / Q000000981:diagnostic imaging; D002972:Cleft Palate / Q000000981:diagnostic imaging*; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods*; D011247:Pregnancy; D016216:Ultrasonography, Prenatal / Q000379:methods*