[Genetic polymorphism of 3 STR loci on chromosome X and its forensic application in Chinese population].
To investigate the genetic polymorphisms of three short tandem repeats loci of chromosome X in Chinese Han population in Chengdu area and its use in forensic science. Three X-chromosome linked short tandem repeat loci were analyzed by PCR followed by polyacrylamide gel electrophoresis. Hardy-Weinberg equilibrium was tested and forensic interested value was calculated . The power of exclution of DXS6804, DXS9896 and GATA144D04 is 0.5990, 0.6220, 0.4280, respectively. The result showed that all the three STR loci were polymorphic among 100 unrelated females and 120 unrelated males from Chinese Han population. Chi(2) tests demonstrated that genotype frequencies in females did not depart from Hardy-Weinberg equilibrium. Three X-chromosome linked short tandem repeat loci have high polymorphism, they can be applied to forensic medicine and population genetics.
Ying
Bin-Wu
BW
Institute of Forensic Medicine, Sichuan University, Chengdu 610 041, China. yingbw@hotmail.com
Shi
Mei-Sen
MS
Deng
Jian-Qiang
JQ
Li
Ying-Bi
YB
Wu
Jin
J
Yan
Jing
J
Zhang
Ji
J
Hou
Yi-Ping
YP
D000483:Alleles; D044466:Asian People; D002681:China / Q000208:ethnology; D041321:Chromosomes, Human, X / Q000235:genetics*; D005260:Female; D005554:Forensic Medicine; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*; D011110:Polymorphism, Genetic