Hylins: bombinins H structurally related peptides from the skin secretion of the Brazilian tree-frog Hyla biobeba.
Two hemolytic peptides were isolated from the skin secretion of the Brazilian Hylidae frog Hyla biobeba, using reversed-phase chromatographic procedures. Hylins b1 and b2 exhibit short linear polypeptide chains, a large number of hydrophobic residues, amidated C termini and hemolytic properties. These two novel peptides are the first examples of bombinins H-like peptides isolated from anurans species not related to Bombina species.
Castro
Mariana S
MS
Brazilian Center for Protein Research, Department of Cell Biology, University of Brasília, University of Brasília, Brasília/DF, Brazil, 70.910-900. mscastro@unb.br
Matsushita
Rubens H
RH
Sebben
Antonio
A
Sousa
Marcelo V
MV
Fontes
Wagner
W
D000595:Amino Acid Sequence; D029845:Amphibian Proteins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D001001:Anura / Q000378:metabolism; D006460:Hemolysin Proteins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D016415:Sequence Alignment; D012867:Skin / Q000737:chemistry / Q000378:metabolism
D029845:Amphibian Proteins; D006460:Hemolysin Proteins; D010455:Peptides; C499430:hylin b1, Hyla biobeba; C499431:hylin b2, Hyla biobeba