Successful use of a polymerized hemoglobin blood substitute in a critically anemic Jehovah's Witness.
A stable, polymerized hemoglobin product has been formulated that overcomes the three traditional hurdles of hemoglobin-based blood substitutes: nephrotoxicity, osmotic diuresis, and blood-borne pathogens. We present a case of a patient with persistent colonic bleeding and a hemoglobin of 2.9 g/100 mL. Since her religious faith prevented her from accepting blood products, we offered a hemoglobin-based substitute and describe the use of this product.
Allison
Genève
G
Department of Medicine and the Medical Intensive Care Unit, Alameda County Medical Center, Oakland, CA, USA.
Feeney
Colin
C
D000740:Anemia / Q000188:drug therapy* / Q000209:etiology; D001802:Blood Substitutes / Q000627:therapeutic use*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000150:complications; D006454:Hemoglobins; D006801:Humans; D033221:Jehovah's Witnesses; D008875:Middle Aged
D001802:Blood Substitutes; D006454:Hemoglobins; C079129:hemoglobin polymer