Lethal infection by Candida (Torulopsis) incospicua complicating orthotopic liver transplantation.
We report here an uncommon case of deep infection by Torulopsis incospicua, associated with multibacterial sepsis and complicated by several mycotic aneurysms of hepatic artery, liver graft necrosis, and hepatic acute failure in a liver orthotopic transplant recipient. Two successive emergency liver transplants were needed, but fast relapses of infection and mycotic aneurysms were experienced. The patient died soon after the third liver transplant; disseminated mycosis was demonstrated by post mortem examination. In conclusion, fungal infection should be considered in cases of spontaneous hepatic artery rupture.
Sonzogni
A
A
Department of Pathology, Azienda Ospedaliera Ospedali Riuniti di Bergamo, 24128 Bergamo, Italy. asonzogni@ospedaliriuniti.bergamo.it
Colledan
M
M
Aluffi
A
A
Gridelli
B
B
Farina
C
C
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D008099:Liver / Q000473:pathology; D016031:Liver Transplantation / Q000473:pathology*; D008297:Male; D009336:Necrosis; D011183:Postoperative Complications / Q000382:microbiology*
D000935:Antifungal Agents