A specific gastrin receptor on plasma membranes of antral smooth muscle.
Plasma membranes with a 17 fold enrichment in 5'-nucleotidase over homogenate were prepared from antral smooth muscle. A specific gastrin receptor on the plasma membranes has been demonstrated. By Scatchard analysis receptor has a Kaff of 2x10(9)M(-1) and a binding capacity of 5x10(-14) moles/mg of membrane protein.
Baur
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Division of Gastroenterology, Palo Alto Veterans Administration Hospital and Stanford University School of Medicine, Stanford, California 94304, USA.
Bacon
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VC
D000818:Animals; D001667:Binding, Competitive; D002462:Cell Membrane / Q000378:metabolism*; D004285:Dogs; D005755:Gastrins / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008861:Microsomes / Q000378:metabolism; D009130:Muscle, Smooth / Q000166:cytology* / Q000378:metabolism*; D043887:Receptor, Cholecystokinin B / Q000378:metabolism*; D013379:Substrate Specificity; D013696:Temperature; D013997:Time Factors
D005755:Gastrins; D043887:Receptor, Cholecystokinin B