A new amide from Asarum forbesii Maxim.
A highly unsaturated new amide, (2E,4Z,8Z,10Z)-N-isobutyl-2,4,8,10-dodecatetraenamide (1), was isolated in very small quantities from the whole plant of Asarum forbesii Maxim. together with four known compounds, (2E,4E,8Z,10E)-N-isobutyl-2,4,8,10-dodecatetraenamide (2), (-)-sesamin (3), (-)-asarinin (4) and (E)-asarone (5). The Z/E isomers, 1 and 2, were separated successfully by developed silver-ion medium-pressure liquid chromatography (SIMPLC). Compound 2 and the two diastereoisomers, 3 and 4, were isolated from this plant for the first time. The characterization of these compounds was achieved by various spectroscopic methods.
Zhang
Feng
F
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.
Chu
Chang-Hu
CH
Xu
Qing
Q
Fu
Shao-Ping
SP
Hu
Jie-Han
JH
Xiao
Hong-Bin
HB
Liang
Xin-Miao
XM
D000577:Amides / Q000737:chemistry / Q000302:isolation & purification*; D030023:Asarum / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy
D000577:Amides