title: Combined hepatocellular-cholangiocarcinoma: a case report.
abstract: Combined hepatocellular-cholangiocarcinoma (HCC-CC) is a rare primary liver tumour. We report a carrier of both HBV and HCV presenting with intermittent abdominal pain, fever, chillness and elevated á-fetoprotein (AFP) of 1197 ng/ml. Computed tomography showed an irregular hypodense mass in the left lateral segment of the liver with vague contrast enhancement and multiple regional lymphadenopathy. Hepatic angiogram showed that the mass was hypovascular and the left portal vein was occluded with a tapered end. Percutaneous ultrasound-guided core needle biopsy of the liver yielded HCC-CC. We suggest that HCC-CC should be considered in hypovascular liver tumours with striking elevation of serum AFP and multiple regional lymphadenopathy.
authors.affiliation: Department of Diagnostic Radiology, Chang Gung Memorial Hospital, Keelung, Taiwan, ROC.
authors.forename: C H
authors.initials: CH
authors.lastname: Toh
authors.forename: Y C
authors.initials: YC
authors.lastname: Cheung
authors.forename: S H
authors.initials: SH
authors.lastname: Ng
authors.forename: C Y
authors.initials: CY
authors.lastname: Lin
authors.forename: S C
authors.initials: SC
authors.lastname: Chan
authors.forename: K K
authors.initials: KK
authors.lastname: Ng
mesh_terms: D000328:Adult; D000792:Angiography / Q000379:methods; D001707:Biopsy, Needle / Q000379:methods; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000473:pathology; D018281:Cholangiocarcinoma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods