title: Clinical and angiographic predictors of luminal changes beyond 6 months after implantation of thicker strut coronary stents.
abstract: BACKGROUND
  Late luminal changes beyond 6 months after thicker strut stent implantation have not been fully elucidated. The purpose of this study was to clarify the clinical and angiographic predictors of late changes in minimal lumen diameter (MLD) after 6-month follow-up of stenting.
  
  
  RESULTS
  Fifty-one lesions from 44 patients who underwent successfully S670/660 stent (Medtronic Vascular, Santa Rosa, CA, USA) implantations without target lesion revascularization were studied at 6-month follow-up and coronary angiography was repeated after the follow-up. Late luminal loss beyond 6 months after stenting significantly correlated with late loss (r=-0.42, p=0.0025) and MLD (r=0.28, p=0.047) at 6-month follow-up. On multivariate analysis, age (p=0.005), diabetes mellitus (p=0.002), hyperlipidemia (p=0.023), smoking (p=0.015), bifurcation lesion (p=0.018), small stent diameter (p=0.001) and MLD at 6-month follow-up (p<0.001) were identified as independent predictors of late luminal loss.
  
  
  CONCLUSIONS
  This study demonstrated that older age, diabetes mellitus, hyperlipidemia, smoking and small stent diameter (<3.0 mm) were associated with late luminal loss beyond 6 months after stenting, and that a bifurcation lesion and small lumen diameter at 6 months were associated with late luminal recovery.
authors.affiliation: Division of Cardiology, St Mary's Hospital, Kurume, Japan. k-sadamatsu@st-mary-med.or.jp
authors.forename: Kenji
authors.initials: K
authors.lastname: Sadamatsu
authors.forename: Hideki
authors.initials: H
authors.lastname: Tashiro
authors.forename: Eriko
authors.initials: E
authors.lastname: Tanaka
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Yamamoto
mesh_terms: D000368:Aged; D015331:Cohort Studies; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000473:pathology*; D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D015607:Stents; D013997:Time Factors