Hypercalcemia caused by iatrogenic hypervitaminosis A.
Vitamin A toxicity produces protean clinical manifestations involving a wide variety of tissues and systems. Hypercalcemia can occasionally be associated with high vitamin A levels, but is rare. In this report we describe a patient who was receiving a commercially prepared enteral feeding formula for 2 years. He developed asymptomatic hypercalcemia and had serum vitamin A levels several fold above normal. Subsequently, a custom-made enteral feed was used which contained negligible amounts of vitamin A. Several months later, vitamin A levels diminished substantially and serum calcium levels returned to normal.
Bhalla
Karan
K
Baptist Health System, 840 Montclair Rd, Suite 317, Birmingham, AL 35213, USA. karan.bhalla@bhsala.com
Ennis
David M
DM
Ennis
Elizabeth D
ED
D000368:Aged; D004750:Enteral Nutrition / Q000009:adverse effects*; D006801:Humans; D006934:Hypercalcemia / Q000097:blood / Q000209:etiology*; D006986:Hypervitaminosis A / Q000097:blood / Q000150:complications*; D007049:Iatrogenic Disease; D008297:Male; D019846:Miller Fisher Syndrome / Q000628:therapy; D014801:Vitamin A / Q000008:administration & dosage / Q000097:blood
D014801:Vitamin A