title: Endometrial fluid visualized through ultrasonography during ovarian stimulation in IVF cycles impairs the outcome in tubal factor, but not PCOS, patients.
abstract: BACKGROUND
  The aim of the present study was to examine the impact of the presence of endometrial fluid (seen through ultrasound) on the outcome of IVF cycles and its association with the aetiology of infertility, in tubal and polycystic ovary syndrome (PCOS) cases specifically.
  
  
  METHODS
  We retrospectively evaluated the charts of all PCOS and tubal factor infertility patients that underwent IVF between June 1, 2001 and May 31, 2002. Twenty-four PCOS and 14 tubal factor infertility patients in whom endometrial fluid was detected were compared with 94 PCOS and 160 tubal factor patients whose stimulation cycles did not show any fluid collection. The main outcome measures were implantation and pregnancy rates.
  
  
  RESULTS
  Implantation rates were lower in the tubal factor patients in the presence of endometrial fluid (6.12% and 21.4%, respectively) in comparison with all other tubal factor infertile patients in whom no fluid accumulation inside the cavity was detected. In PCOS cycles there was no significance in patients with presence of endometrial fluid in comparison with the all other PCOS cycles without any fluid accumulation.
  
  
  CONCLUSIONS
  When fluid collection inside the endometrial cavity is first seen during ovarian stimulation of PCOS patients undergoing IVF, embryo transfer can be performed safely if the fluid has disappeared and not returned by the day of embryo transfer. However, in tubal factor cycles one should think of either cancellation of the cycle or cryopreservation of all embryos.
authors.affiliation: German Hospital IVF Unit, Bahceci Women Health Care Center, Istanbul, Turkey.
authors.forename: Mehmet Ali
authors.initials: MA
authors.lastname: Akman
authors.forename: Halit Firat
authors.initials: HF
authors.lastname: Erden
authors.forename: Mustafa
authors.initials: M
authors.lastname: Bahceci
mesh_terms: D000328:Adult; D001826:Body Fluids / Q000000981:diagnostic imaging* / Q000378:metabolism; D004624:Embryo Transfer; D004717:Endometrium / Q000000981:diagnostic imaging / Q000378:metabolism; D005184:Fallopian Tube Diseases / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000378:metabolism; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D015994:Incidence; D007247:Infertility, Female / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000378:metabolism; D010062:Ovulation Induction; D011085:Polycystic Ovary Syndrome / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000378:metabolism; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D014463:Ultrasonography