Actomyosin systems of biological motility.
Evolution of notions on the molecular mechanism of muscle contraction and other events based on the actin-myosin interaction, from the middle of XX century to the present time, is briefly reviewed, including recent views on the functioning of the myosin head as a "molecular motor". The results of structural and functional studies on the myosin head performed by the author and his colleagues using differential scanning calorimetry are also reviewed.
Levitsky
D I
DI
Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119992, Russia. levitsky@inbi.ras.ru
D000205:Actomyosin / Q000378:metabolism*; D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D020409:Molecular Motor Proteins / Q000378:metabolism*; D009119:Muscle Contraction / Q000502:physiology*; D009218:Myosins / Q000737:chemistry / Q000378:metabolism*
D020409:Molecular Motor Proteins; D000205:Actomyosin; D000251:Adenosine Triphosphatases; D009218:Myosins