[Exploration of the hidden layers of genome].
In recent years, geneticists have been exploring the less visible parts of genome more thoroughly. They are coming to realize that these much more layers of genomic information, distinct from the protein-coding genes, connect in surprisingly deep and potent ways to growth and development in the high eukaryotes. This article reviews a number of startling observations about the extent of non-protein-coding RNA transcriptions, DNA methylation and covalent histone modifications in the complex organisms.
Cao
Geng-Sheng
GS
State Key Laboratories of Agrobiotechnology, China Agricultural University, Beijing 100 094, China. gscao@henu.edu.cn
Liu
Ai-Lian
AL
Li
Ning
N
D000107:Acetylation; D000818:Animals; D019175:DNA Methylation; D016678:Genome; D006657:Histones / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D007438:Introns; D011544:Pseudogenes; D022661:RNA, Untranslated / Q000502:physiology
D006657:Histones; D022661:RNA, Untranslated