title: High resolution electrocardiography in healthy dogs: time domain parameters and comparison of the non-stationary (Wigner distribution) versus standard stationary frequency domain analysis methods.
abstract: Fractionated heart activation can be detected as late potentials from surface recordings of signal-averaged electrocardiograms (SA ECG) which are considered as a marker of sustained ventricular tachycardia. For animal studies, reference values in time and frequency domain analyses are essentially missing. In the present study, we have established reference values in SA ECG time domain analysis and time-frequency representation of heart activation in healthy dogs. A group of 25 healthy mongrel dogs (body weight 12-15 kg) was investigated. Wigner distribution and our modification of Fast Fourier transform (FFT), gliding window FFT, was applied in SA ECG frequency domain analysis. Reference values in time domain SA ECG were established. Time and voltage criteria were adapted to short duration of heart cycle and fast voltage decrement of the QRS complex in dogs. Wigner distribution and gliding window FFT were applied in order to describe mean heart activation in the frequency domain. Contribution of higher frequencies (30-80 Hz) was detected by both frequency analysis methods in the second third of ventricular activation in healthy animals. Presented results could offer a basis for further experimental arrhythmologic studies.
authors.affiliation: Institute of Pathophysiology, Medical School, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovak Republic.
authors.forename: M
authors.initials: M
authors.lastname: Bernadic
authors.forename: P
authors.initials: P
authors.lastname: Hubka
authors.forename: P
authors.initials: P
authors.lastname: Slavkovský
authors.forename: H
authors.initials: H
authors.lastname: Petrásová
authors.forename: J
authors.initials: J
authors.lastname: Holzerová
authors.forename: D
authors.initials: D
authors.lastname: Maasová
authors.forename: L
authors.initials: L
authors.lastname: Zlatos Zlatos
authors.forename: B
authors.initials: B
authors.lastname: Mladosievicová
authors.forename: I
authors.initials: I
authors.lastname: Hulín
mesh_terms: D000465:Algorithms; D000818:Animals; D003936:Diagnosis, Computer-Assisted / Q000379:methods* / Q000592:standards; D004285:Dogs / Q000502:physiology*; D004562:Electrocardiography / Q000379:methods* / Q000592:standards / Q000662:veterinary*; D005583:Fourier Analysis; D006329:Heart Conduction System / Q000502:physiology*; D006339:Heart Rate / Q000502:physiology*; D009200:Myocardial Contraction / Q000502:physiology*; D012016:Reference Values; D013997:Time Factors