title: Cocaine flakes versus tetracaine/adrenaline solution for local anaesthesia in septoplasty.
abstract: The aim of this prospective study was to evaluate the efficacy of cocaine flakes compared to tetracaine with adrenaline solution, as a local anaesthetic for patients undergoing septoplasty. From January 2001 to December 2002, 220 patients underwent septoplasty under local anaesthesia. Patients were randomly classified in group A and group B, where cocaine and the solution of tetracaine/adrenaline were used respectively. A visual analogue scale was used to evaluate the severity of the patients'pain during the procedure. The patients of group B showed a statistically significant lower pain score than patients of group A. We believe that the solution of tetracaine/adrenaline is an effective and safe anaesthetic for patients undergoing septoplasty under local anaesthesia.
authors.affiliation: Department of Otorhinolaryngology, University of Crete School of Medicine, Heraklion, Crete, Greece. jbizakis@med.uoc.gr
authors.forename: John G
authors.initials: JG
authors.lastname: Bizakis
authors.forename: Vassilios A
authors.initials: VA
authors.lastname: Lachanas
authors.forename: Emmanuel I
authors.initials: EI
authors.lastname: Drivas
authors.forename: Dionysios E
authors.initials: DE
authors.lastname: Kyrmizakis
authors.forename: Emmanuel P
authors.initials: EP
authors.lastname: Prokopakis
authors.forename: Antonios A
authors.initials: AA
authors.lastname: Benakis
authors.forename: Emmanuel S
authors.initials: ES
authors.lastname: Helidonis
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000772:Anesthesia, Local; D000779:Anesthetics, Local / Q000008:administration & dosage*; D003042:Cocaine / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D004837:Epinephrine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009300:Nasal Septum / Q000601:surgery*; D010147:Pain Measurement; D019999:Pharmaceutical Solutions; D011446:Prospective Studies; D013748:Tetracaine / Q000008:administration & dosage*; D014662:Vasoconstrictor Agents / Q000008:administration & dosage*
chemical_list: D000779:Anesthetics, Local; D019999:Pharmaceutical Solutions; D014662:Vasoconstrictor Agents; D013748:Tetracaine; D003042:Cocaine; D004837:Epinephrine