title: Cationic carbon nanotubes bind to CpG oligodeoxynucleotides and enhance their immunostimulatory properties.
abstract: Functionalized cationic carbon nanotubes are able to form a stable complex with CpG ODN based on charge interaction and to increase the immunostimulatory activity of CpG motifs.
authors.affiliation: Institut de Biologie Moléculaire et Cellulaire, UPR9021 CNRS, Immunologie et Chimie Thérapeutiques, 67084 Strasbourg, France. A.Bianco@ibmc.u-strasbg.fr
authors.forename: Alberto
authors.initials: A
authors.lastname: Bianco
authors.forename: Johan
authors.initials: J
authors.lastname: Hoebeke
authors.forename: Sylvie
authors.initials: S
authors.lastname: Godefroy
authors.forename: Olivier
authors.initials: O
authors.lastname: Chaloin
authors.forename: Davide
authors.initials: D
authors.lastname: Pantarotto
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Briand
authors.forename: Sylviane
authors.initials: S
authors.lastname: Muller
authors.forename: Maurizio
authors.initials: M
authors.lastname: Prato
authors.forename: Charalambos D
authors.initials: CD
authors.lastname: Partidos
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage* / Q000737:chemistry*; D000818:Animals; D002412:Cations; D018899:CpG Islands / Q000276:immunology*; D007371:Interferon-gamma / Q000378:metabolism*; D015850:Interleukin-6 / Q000378:metabolism; D007700:Kinetics; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology; D051379:Mice; D037742:Nanotubes, Carbon / Q000737:chemistry*; D009841:Oligonucleotides / Q000008:administration & dosage / Q000737:chemistry* / Q000276:immunology*; D020349:Surface Plasmon Resonance
chemical_list: D000276:Adjuvants, Immunologic; D002412:Cations; D015850:Interleukin-6; D037742:Nanotubes, Carbon; D009841:Oligonucleotides; D007371:Interferon-gamma