title: UK-2A, B, C and D, novel antifungal antibiotics from streptomyces sp. 517-02 VI (3). Role of substituents on dilactone ring of UK-2A and antimycin A3 against generation of reactive oxygen species in porcine renal proximal tubule LLC-PK1 cells.
authors.affiliation: Graduate School of Science, Osaka City University 3-3-138 Sugimoto, Sumiyoshi-ku, Osaka 558-8585, Japan. kfujita@sci.osaka-cu.ac.jp
authors.forename: Ken-Ichi
authors.initials: K
authors.lastname: Fujita
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Kiso
authors.forename: Yoshinosuke
authors.initials: Y
authors.lastname: Usuki
authors.forename: Toshio
authors.initials: T
authors.lastname: Tanaka
authors.forename: Makoto
authors.initials: M
authors.lastname: Taniguchi
mesh_terms: D000818:Animals; D000968:Antimycin A / Q000737:chemistry / Q000494:pharmacology*; D002460:Cell Line; D007687:Kidney Tubules, Proximal / Q000187:drug effects* / Q000378:metabolism; D007783:Lactones / Q000737:chemistry / Q000494:pharmacology*; D011725:Pyridines / Q000737:chemistry / Q000494:pharmacology*; D017382:Reactive Oxygen Species / Q000378:metabolism*; D013329:Structure-Activity Relationship; D013552:Swine
chemical_list: D007783:Lactones; D011725:Pyridines; D017382:Reactive Oxygen Species; C101439:UK 2A; D000968:Antimycin A