title: Prevention of hepatic infarction as acute-phase complication of TIPS by temporary balloon occlusion in a patient with primary myelofibrosis.
abstract: Severe acute liver dysfunction occurred following transjugular intrahepatic portosystemic shunt (TIPS) creation in a patient with massive ascites due to portal hypertension associated with primary myelofibrosis. On US and TIPS venography, we considered that the acute liver ischemia was induced by TIPS. To avoid diffuse hepatic infarction and irreversible liver damage, a balloon catheter was inserted transjugularly into the TIPS tract and occluded it to increase portal venous flow toward the peripheral liver parenchyma. The laboratory data indicating hepatic dysfunction were improved after the procedure. We should pay attention to the possible occurrence of acute hepatic ischemia and infarction after TIPS creation even in a case of noncirrhotic portal hypertension. In such cases, temporary balloon occlusion of TIPS is an effective therapeutic method, probably as a result of inducing the development of arterial compensation through the peribiliary plexus.
authors.affiliation: Department of Radiology, Kanazawa University School of Medicine, Ishikawa, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Osamu
authors.initials: O
authors.lastname: Matsui
authors.forename: Jun
authors.initials: J
authors.lastname: Yoshikawa
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Gabata
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Kawamori
authors.forename: Junichiro
authors.initials: J
authors.lastname: Sanada
authors.forename: Noboru
authors.initials: N
authors.lastname: Terayama
authors.forename: Masumi
authors.initials: M
authors.lastname: Kadoya
mesh_terms: D000210:Acute-Phase Reaction / Q000209:etiology*; D021721:Balloon Occlusion; D006801:Humans; D006975:Hypertension, Portal / Q000628:therapy; D007238:Infarction / Q000517:prevention & control*; D007511:Ischemia / Q000209:etiology; D008099:Liver / Q000098:blood supply*; D008102:Liver Circulation / Q000502:physiology; D008297:Male; D008875:Middle Aged; D017082:Portal Pressure / Q000502:physiology; D019168:Portasystemic Shunt, Transjugular Intrahepatic / Q000009:adverse effects*; D055728:Primary Myelofibrosis / Q000150:complications*