[Effects of different positive end expiratory pressure levels on resting energy expenditure measured by indirect calorimeter in patients with pressure-controlled ventilation].
OBJECTIVE
To identify variations during measurements of resting energy expenditure (REE), oxygen consumption (VO2) and CO2 production (VCO2) by indirect calorimetry (IC) in patients with pressure-controlled ventilation and different levels of positive end expiratory pressure (PEEP).


METHODS
Prospective and comparative study.


METHODS
Intensive care unit (ICU) of a university-affiliated hospital.


RESULTS
REE, VO2, and VCO2 were measured by IC in nine patients with pressure-controlled ventilation and different levels of PEEP. Paired t Wilcoxon and coeficient of variation tests for all measurements were carried out. Decrease in REE, VCO2, and VO2 was observed with increments in PEEP, these changes related with a concomitant reduction in VE. Coefficient of variation during IC was above 6%, and was lower in three patients who maintained the same VE throughout the study.


CONCLUSIONS
Measurement of REE by IC is reliable at various levels of PEEP, and it improves if VE remains constant throughout measurement. Respiratory quotient (RQ) in this setting is not accurate.
Castañón-González
Jorge A
JA
Unidad de Cuidados Intensivos y Medicina Crítica, Hospital de Especialidades Dr. Bernardo Sepúlveda del Centro Médico Nacional Siglo XXI, IMSS, México DF, México. jorgec@prodigy.net.mx
Satué-Rodríguez
Julián
J
Camacho-Juárez
José Sergio
JS
Carrillo-Rosales
Francisco
F
León-Gutiérrez
Marco Antonio
MA
Miranda-Ruiz
Rogelio
R
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002153:Calorimetry, Indirect; D004734:Energy Metabolism; D006801:Humans; D008875:Middle Aged; D011175:Positive-Pressure Respiration / Q000379:methods*; D011446:Prospective Studies; D012146:Rest / Q000502:physiology*