title: [Mathematical modeling and simulation study of the heart rate feedback regulation system].
abstract: The physiological feedback regulation mechanism of the heart rate variation due to the blood pressure variation is studied. The continuous closed-loop mathematical model of the heart rate feedback regulation system is constructed. Numerical simulation is completed based on the above model. The simulation results demonstrate that the regulation system has the ability to constrain the fluctuation of the blood pressure to certain extent. The results are helpful for the pathological studies of some hypertensive diseases.
authors.affiliation: Simulation Center, Harbin Institute of Technology, Harbin 150006, China. sxp@vip.163.com
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Shi
authors.forename: Yuyun
authors.initials: Y
authors.lastname: Zhu
mesh_terms: D001794:Blood Pressure / Q000502:physiology*; D003198:Computer Simulation; D025461:Feedback, Physiological; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008433:Mathematics; D008955:Models, Cardiovascular