title: Hylins: bombinins H structurally related peptides from the skin secretion of the Brazilian tree-frog Hyla biobeba.
abstract: Two hemolytic peptides were isolated from the skin secretion of the Brazilian Hylidae frog Hyla biobeba, using reversed-phase chromatographic procedures. Hylins b1 and b2 exhibit short linear polypeptide chains, a large number of hydrophobic residues, amidated C termini and hemolytic properties. These two novel peptides are the first examples of bombinins H-like peptides isolated from anurans species not related to Bombina species.
authors.affiliation: Brazilian Center for Protein Research, Department of Cell Biology, University of Brasília, University of Brasília, Brasília/DF, Brazil, 70.910-900. mscastro@unb.br
authors.forename: Mariana S
authors.initials: MS
authors.lastname: Castro
authors.forename: Rubens H
authors.initials: RH
authors.lastname: Matsushita
authors.forename: Antonio
authors.initials: A
authors.lastname: Sebben
authors.forename: Marcelo V
authors.initials: MV
authors.lastname: Sousa
authors.forename: Wagner
authors.initials: W
authors.lastname: Fontes
mesh_terms: D000595:Amino Acid Sequence; D029845:Amphibian Proteins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D001001:Anura / Q000378:metabolism; D006460:Hemolysin Proteins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D016415:Sequence Alignment; D012867:Skin / Q000737:chemistry / Q000378:metabolism
chemical_list: D029845:Amphibian Proteins; D006460:Hemolysin Proteins; D010455:Peptides; C499430:hylin b1, Hyla biobeba; C499431:hylin b2, Hyla biobeba