Ultraviolet light and lysosome activity.
The abdominal skin of guinea pigs was irradiated by a Xenon short arc lamp with glass filters. Acid phosphatase and beta-glucuronidase activity increased in the irradiated skin. The change of acid phosphatase is slow and mild in intensity, while that of beta-glucuronidase is quick and high in degree. The activity of acid phosphatase is influenced equally by light with filters of UV-25, UV-27, UV-29, and UV-31, while that of beta-glucuronidase is affected more mildly by light with a UV-31 filter than with any of the other three filters. These findings suggest that there is a close relationship between cutaneous changes induced by ultraviolet light and changes in lysosome activity, and that energy required to induce changes in enzyme activity is much less than energy required to produce erythema.
Aoki
K
K
Department of Dermatology, Osaka City University Medical School, Abeno-Ku, Osaka, 545 Japan.
Saito
T
T
D000135:Acid Phosphatase / Q000528:radiation effects; D000818:Animals; D005260:Female; D005966:Glucuronidase / Q000528:radiation effects; D006168:Guinea Pigs; D008247:Lysosomes / Q000201:enzymology / Q000528:radiation effects*; D012867:Skin / Q000528:radiation effects*; D014466:Ultraviolet Rays
D000135:Acid Phosphatase; D005966:Glucuronidase