title: [Differential diagnosis of bullous skin lesions in neonates: pemphigoid gestationis].
abstract: The clinical relevance of bullous skin diseases in newborns varies widely. We present the case of a preterm, 35 weeks of gestation, infant who was admitted to our hospital with skin lesions on face, thorax and plantae. There were no other pathological findings on clinical and neurological examinations. During another pregnancy the mother of the child had already suffered from pemphigoid gestationis. In the blood of the newborn complement-fixing auto-antibodies against BP180, the common antigen of pemphigoid gestationis and bullous pemphigoid, were detected. The skin lesions disappeared after a few days of local antiseptic therapy. Pemphigoid gestations is a rare autoimmune dermatosis in pregnancy. The frequency of skin lesions in newborns of mothers with pemphigoid gestationis is estimated to about 5 -- 10 %.
authors.affiliation: Universitäts-Kinderklinik Würzburg.
authors.forename: C
authors.initials: C
authors.lastname: König
authors.forename: J
authors.initials: J
authors.lastname: Wirbelauer
authors.forename: D
authors.initials: D
authors.lastname: Zillikens
authors.forename: C P
authors.initials: CP
authors.lastname: Speer
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D010391:Pemphigoid, Bullous / Q000150:complications* / Q000175:diagnosis* / Q000276:immunology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000276:immunology; D047928:Premature Birth / Q000150:complications* / Q000175:diagnosis* / Q000276:immunology