Pathbase: a new reference resource and database for laboratory mouse pathology.
Pathbase (http://www.pathbase.net) is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of mutant or genetically engineered mice and their background strains. The metadata for the images, which allows retrieval and interoperability with other databases, is derived from a series of orthogonal ontologies and controlled vocabularies. One of these controlled vocabularies, MPATH, was developed by the Pathbase Consortium as a formal description of the content of mouse histopathological images. The database currently has over 1000 images on-line with 2000 more under curation and presents a paradigm for the development of future databases dedicated to aspects of experimental biology.
Schofield
Paul N
PN
Department of Anatomy, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK. PS@mole.bio.cam.ac.uk
Bard
Jonathan B L
JB
Boniver
Jacques
J
Covelli
Vincenzo
V
Delvenne
Philippe
P
Ellender
Michele
M
Engstrom
Wilhelm
W
Goessner
Wolfgang
W
Gruenberger
Michael
M
Hoefler
Heinz
H
Hopewell
John W
JW
Mancuso
Mariateresa
M
Mothersill
Carmel
C
Quintanilla-Martinez
Leticia
L
Rozell
Bjorn
B
Sariola
Hannu
H
Sundberg
John P
JP
Ward
Andrew
A
D000818:Animals; D019295:Computational Biology; D016208:Databases, Factual; D005838:Genotype; D016247:Information Storage and Retrieval; D020407:Internet; D051379:Mice; D009154:Mutation; D010336:Pathology; D010641:Phenotype; D018875:Vocabulary, Controlled