[Discovery of a novel reassortant H1N2 influenza virus].
Three strains of influenza A virus were isolated from patients suffering from influenza like disease in Railway Hygiene and Anti-epidemic Station of Taiyuan in January 1996. The identification results by serological method indicated that the isolates were different from H1N2 subtype of influenza A virus isolated from men in 1989 and 1992 and that their HA antigenicity was similar to that of A/RP/8/34 (H1N1) virus, but distinguishable from that of influenza A (H1N1) virus circulating in mans recently. The comparison of migration patterns of the RNA among the isolates, the A/PR//34 (H1N1) and the A/Wuhan/359/95 (H3N2) viruses revealed that the migration patterns of RNA 1-4 segments of the isolates were similar to those of A/PR/8/34 (H1N1) virus, but those of RNA 5-6 segments were indistinguishable from those of A/Wuhan/359/95 (H3N2) strain. However, the migration patterns of RNA 7-8 segments of the isolates were not only different from those of A/PR/8/34 (H1N1) virus, but also distingrasgable from those of A/Wuhan/359/95 (H3N2) strain. Therefore, it could be considered that the isolates were a novel reassortant H1N2 influenza A virus.
Guo
Y
Y
Institute of Virology, Chinese Academy of Preventive Medicine, Beijing 100052.
Qi
J
J
Wang
M
M
Wu
L
L
Chang
Y
Y
Guo
J
J
Dong
J
J
Mo
Y
Y
Zheng
L
L
D000293:Adolescent; D000328:Adult; D000818:Animals; D002645:Chickens; D002648:Child; D006801:Humans; D009980:Influenza A virus / Q000145:classification* / Q000235:genetics*; D008297:Male; D051379:Mice; D012367:RNA, Viral / Q000235:genetics; D016865:Reassortant Viruses / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D013552:Swine; D055815:Young Adult
D012367:RNA, Viral