title: Solitary fibrous tumors of the pleura: surgical outcome and clinical course.
abstract: BACKGROUND
  The aim of this study was to define more precisely the surgical outcome and clinical course of solitary fibrous tumors of the pleura.
  
  
  METHODS
  We conducted a retrospective review of the clinical records of patients who had undergone surgical resection for benign and malignant solitary fibrous tumors of the pleura during a 10-year period (1993 to 2003).
  
  
  RESULTS
  Sixty-three patients were enrolled in the study (men, 29; women, 34; mean age, 49.6 years). Thirty-six patients (57.1%) were symptomatic at the time of diagnosis. Resection was performed through a thoracotomy (n = 37), by means of video-assisted thoracoscopy (n = 22), or through a sternotomy (n = 4). Mass excision only was performed in 34 cases, and en bloc excision including adjacent structures was performed in 29 cases. Forty-four cases (69.8%) were benign and 19 (30.2%) were malignant. Local recurrences occurred in three cases and distant metastases in eight. Recurrences occurred only in malignancy. Symptomatic presentation and the impression of a nonpleural tumor by imaging study were found to be related to a malignant pathologic diagnosis. The radiologic impression of solitary fibrous tumors of the pleura was also related to mass excision only.
  
  
  CONCLUSIONS
  For malignant cases, complete surgical resection may be insufficient for the cure. Therefore, further study should be performed to define the role of preoperative and postoperative systemic treatment.
authors.affiliation: Department of Thoracic Surgery, Seoul National University, Seoul, South Korea.
authors.forename: Sook Hwan
authors.initials: SH
authors.lastname: Sung
authors.forename: Jee-Won
authors.initials: JW
authors.lastname: Chang
authors.forename: Jhingook
authors.initials: J
authors.lastname: Kim
authors.forename: Kyung Soo
authors.initials: KS
authors.lastname: Lee
authors.forename: Jungho
authors.initials: J
authors.lastname: Han
authors.forename: Seung Il
authors.initials: SI
authors.lastname: Park
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D033162:Incidental Findings; D015993:Life Tables; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D018218:Neoplasms, Fibrous Tissue / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D010997:Pleural Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D013249:Sternum / Q000601:surgery; D020775:Thoracic Surgery, Video-Assisted / Q000706:statistics & numerical data; D013908:Thoracotomy / Q000706:statistics & numerical data; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome