title: Treatment of Nevus comedonicus with topical tazarotene and calcipotriene.
abstract: Nevus comedonicus is a rare developmental defect of the pilosebaceous unit. It is also thought to be a variant of epidermal nevus. Previously reported treatments include surgical excision, CO2 laser, dermabrasion, extraction, topical retinoic acid, and numerous topical keratolytics. We present a case of a 7-year-old boy with bilateral nevus comedonicus who experienced cosmetic improvement with topical tazarotene and calcipotriene cream. This combination represents a novel therapeutic approach to the treatment of this cutaneous abnormality.
authors.affiliation: Department of Dermatology, Mayo Clinic.
authors.forename: Steven B
authors.initials: SB
authors.lastname: Deliduka
authors.forename: Pearl C
authors.initials: PC
authors.lastname: Kwong
mesh_terms: D000279:Administration, Cutaneous; D002117:Calcitriol / Q000008:administration & dosage / Q000031:analogs & derivatives*; D002648:Child; D003879:Dermatologic Agents / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005148:Facial Dermatoses / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008297:Male; D009508:Nevus, Pigmented / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D009539:Nicotinic Acids / Q000008:administration & dosage; D013544:Sweat Gland Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D012176:Retinoids
chemical_list: D002117:Calcitriol; D003879:Dermatologic Agents; D009539:Nicotinic Acids; C055085:calcipotriene; C086827:tazarotene; D012176:Retinoids