[Asthma and pregnancy -- efficacy and safety of medication during pregnancy].
Bronchial asthma is one of the most common medical problems in pregnancy, with prevalance around 4-7 %. Asthma clinical course is variable, with worsening of symptoms in one third of the cases. The most critical period occurs between the 24th and 36th week of gestation. Symptoms usually regress completely after delivery during the following three months and they are expected to recur, with the same pattern, in subsequent pregnancies. Asthma control during pregnancy depends on pregnant patient education and safe medication, preferably inhaled, that prevents crises. In chronic asthma, usually prescribed drugs (inhaled corticosteroids: beclometasone and budesonide) are effective and safe to the fetus. There are several drugs to be added to inhaled steroids -- beta agonists bronchodilators: short and long acting -- according to the severity of bronchial constriction and frequency of crises. Treatment of acute asthma should follow recommended guidelines, since uncontrolled asthma increases more the risk of pregnancy complications (low birth weight and premature delivery) than the eventual medication risks to pregnancy.
Freitas
Maria Da Graça
Mda G
Hospital CUF, Descobertas, Lisboa.
Duarte
Ana Cristina
AC
D000208:Acute Disease; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D011247:Pregnancy / Q000502:physiology; D011248:Pregnancy Complications / Q000188:drug therapy*; D012119:Respiration
D018927:Anti-Asthmatic Agents