title: Physical training and fatigue, fitness, and quality of life in Guillain-Barré syndrome and CIDP.
abstract: Many patients with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP) experience excessive fatigue, which may persist for years and reduce quality of life. The authors performed a 12-week study of bicycle exercise training in 20 patients with severe fatigue, 16 with relatively good recovery from GBS, and 4 with stable CIDP. Training seemed well tolerated, and self-reported fatigue scores decreased 20% (p = 0.001). Physical fitness, functional outcome, and quality of life were improved.
authors.affiliation: Department of Neurology, Erasmus Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands. m.garssen@erasmusmc.nl
authors.forename: M P J
authors.initials: MP
authors.lastname: Garssen
authors.forename: J B J
authors.initials: JB
authors.lastname: Bussmann
authors.forename: P I M
authors.initials: PI
authors.lastname: Schmitz
authors.forename: A
authors.initials: A
authors.lastname: Zandbergen
authors.forename: T G
authors.initials: TG
authors.lastname: Welter
authors.forename: I S J
authors.initials: IS
authors.lastname: Merkies
authors.forename: H J
authors.initials: HJ
authors.lastname: Stam
authors.forename: P A
authors.initials: PA
authors.lastname: van Doorn
mesh_terms: D000328:Adult; D000368:Aged; D001007:Anxiety / Q000209:etiology / Q000517:prevention & control; D001642:Bicycling; D003863:Depression / Q000209:etiology / Q000517:prevention & control; D005080:Exercise Test; D005081:Exercise Therapy; D005221:Fatigue / Q000209:etiology / Q000517:prevention & control* / Q000523:psychology; D005240:Feasibility Studies; D005260:Female; D020275:Guillain-Barre Syndrome / Q000150:complications / Q000523:psychology / Q000534:rehabilitation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption; D010809:Physical Fitness; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000150:complications / Q000523:psychology / Q000534:rehabilitation*; D011788:Quality of Life; D012720:Severity of Illness Index; D016896:Treatment Outcome