Three-component reaction of aryl diazoacetates, alcohols, and aldehydes (or imines): evidence of alcoholic oxonium ylide intermediates.
The Rh(II)-catalyzed three-component reaction of aryl diazoacetates, alcohols and aldehydes was explored, which provided evidence of alcoholic oxonium ylide formation for O-H insertion. A new C-C bond formation reaction where alcoholic oxonium ylides were trapped by electron-deficient aryl aldehydes (or imines) was realized.
Lu
Chong-Dao
CD
Key Laboratory for Asymmetric Synthesis and Chirotechnology of Sichuan Province, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China.
Liu
Hui
H
Chen
Zhi-Yong
ZY
Hu
Wen-Hao
WH
Mi
Ai-Qiao
AQ