title: Inhibition of E. coli beta-hydroxydecanoyl thioester dehydrase by ppGpp.
abstract: Guanosine-5'-diphosphate-3'-diphosphate was found to inhibit beta-hydroxydecanoyl thioester dehydrase of E. coli at concentrations corresponding to those generated in vivo during amino acid starvation of rel+ cells.
authors.affiliation: James Bryant Conant Laboratory, Harvard University, Cambridge, Massachusetts 02138, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Stein
authors.forename: K E
authors.initials: KE
authors.lastname: Bloch
mesh_terms: D004791:Enzyme Inhibitors / Q000494:pharmacology*; D004926:Escherichia coli / Q000201:enzymology*; D054889:Fatty Acid Synthase, Type II; D006159:Guanosine Tetraphosphate / Q000494:pharmacology*; D006836:Hydro-Lyases / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: D004791:Enzyme Inhibitors; D006159:Guanosine Tetraphosphate; D006836:Hydro-Lyases; C047118:3-hydroxyacyl-(acyl-carrier-protein) dehydratase; D054889:Fatty Acid Synthase, Type II