title: Assessment of the effect of cardiac resynchronization therapy on intraventricular mechanical synchronicity by regional volumetric changes.
abstract: A new echocardiographic technology, the timing of regional volumetric changes by 3-dimensional echocardiography, was applied to assess intraventricular mechanical synchronicity in 13 patients who had received cardiac resynchronization therapy (CRT). When biventricular pacing was withheld, left ventricular (LV) asynchrony occurred as reflected by these echocardiographic parameters, whereas LV volume increased and the ejection fraction decreased. Further studies are needed to explore whether this novel method can be used to select suitable candidates for CRT and to predict a favorable response.
authors.affiliation: Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhang
authors.forename: Cheuk-Man
authors.initials: CM
authors.lastname: Yu
authors.forename: Jeffrey Wing-Hong
authors.initials: JW
authors.lastname: Fung
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yat-Sun
authors.initials: YS
authors.lastname: Chan
authors.forename: Hamish Chi-Kin
authors.initials: HC
authors.lastname: Chan
authors.forename: Gabriel W K
authors.initials: GW
authors.lastname: Yip
authors.forename: John E
authors.initials: JE
authors.lastname: Sanderson
mesh_terms: D002304:Cardiac Pacing, Artificial; D019560:Echocardiography, Three-Dimensional; D005260:Female; D006333:Heart Failure / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy*; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged