Hypercalcemia induced by excessive intake of calcium supplement, presenting similar findings of primary hyperparathyroidism.
A 31-year-old woman had ureterolithiasis related to hypercalcemia, and when she was admitted to our hospital ultrasonography and technetium-99 m sestamibi scintigraphy did not detect parathyroid abnormalities. Serum concentrations of calcium and intact parathyroid hormone were 9.7 mg/dl and 153 pg/ml, respectively, but subsequently increased to 13.5 mg/dl and decreased to 10 pg/ml, respectively. Diagnostic interview revealed that she had been taking excessive calcium supplements of 3,000 5,000 mg/day because she was worried about developing osteoporosis. Her hypercalcemia was cured after she stopped taking the supplements. The present case indicates that calcium supplementation of more than 2,500 mg/day elicits adverse effects on body mineral balance. Clear indications of the upper limits to supplements should be made known to the consumers.
Kato
Yoshiyuki
Y
Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, 8-1 Kawata-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
Sato
Kanji
K
Sata
Akira
A
Omori
Kazue
K
Nakajima
Kishiko
K
Tokinaga
Kotaro
K
Obara
Takao
T
Takano
Kazue
K
D000328:Adult; D002118:Calcium / Q000097:blood; D002136:Calcium, Dietary / Q000097:blood / Q000506:poisoning*; D019587:Dietary Supplements / Q000506:poisoning*; D062787:Drug Overdose; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000097:blood / Q000139:chemically induced*; D006961:Hyperparathyroidism / Q000473:pathology; D010281:Parathyroid Hormone / Q000097:blood; D010758:Phosphorus / Q000097:blood
D002136:Calcium, Dietary; D010281:Parathyroid Hormone; D010758:Phosphorus; D002118:Calcium