Is bone marrow trephine biopsy always mandatory in staging Hodgkin's disease?
We reviewed data from 690 adult patients with Hodgkin's disease (HD) to determine whether bone marrow trephine biopsy (BMTB) is mandatory for all patients. The data suggest that it is not necessary in clinical stage I-IIA. However, bilateral BMTB is recommended in the presence of B symptoms also in patients with localized stage disease.
Cavalieri
Elena
E
Anselmo
Anna Paola
AP
Gianfelici
Valentina
V
Frattarelli
Natalia
N
Pescarmona
Edoardo
E
Foà
Robin
R
Pulsoni
Alessandro
A
D000328:Adult; D000368:Aged; D001706:Biopsy / Q000379:methods; D001854:Bone Marrow Cells / Q000473:pathology*; D005260:Female; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods; D019564:Unnecessary Procedures