Evidence-based guidelines for the management of neutropenia following outpatient hematopoietic stem cell transplantation.
Hematopoietic stem cell transplantation (HSCT) involves the transfer of stem cells to establish hematopoiesis in patients who have received myeloablative chemotherapy with or without whole body irradiation. Following high-dose therapy and HSCT, all patients experience a period of neutropenia. Outpatient care delivery models place expanded responsibilities on patients and their families for the management of this treatment side effect. Proactive management of neutropenia is critical to decrease the depth and duration of neutropenia following HSCT, limit exposure to opportunistic and nosocomial pathogens, and ensure prompt intervention should febrile neutropenia or infection develop. Patient and family education, psychosocial support, and coordination of care are key nursing responsibilities.
West
Fran
F
Cancer Center Methodist University Hospital, Memphis, TN, USA. fwest@utcancer.com
Mitchell
Sandra A
SA
D000553:Ambulatory Care / Q000458:organization & administration*; D002405:Catheterization, Central Venous / Q000009:adverse effects / Q000451:nursing; D003115:Colony-Stimulating Factors / Q000627:therapeutic use; D004509:Education, Nursing, Continuing / Q000458:organization & administration; D019317:Evidence-Based Medicine; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D017053:Infection Control / Q000458:organization & administration; D007318:Inservice Training / Q000458:organization & administration; D007958:Leukocyte Count; D016294:Models, Nursing; D009503:Neutropenia / Q000097:blood / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D009504:Neutrophils; D024802:Nurse's Role; D015399:Nursing Research / Q000458:organization & administration; D009859:Oncology Nursing / Q000193:education / Q000458:organization & administration*; D009910:Oral Hygiene / Q000379:methods / Q000451:nursing / Q000592:standards; D010353:Patient Education as Topic / Q000458:organization & administration; D017410:Practice Guidelines as Topic; D016730:Program Development; D015397:Program Evaluation; D012307:Risk Factors; D017592:Skin Care / Q000379:methods / Q000451:nursing / Q000592:standards
D003115:Colony-Stimulating Factors