IgA nephropathy in renal allografts-recurrence and graft dysfunction.
With time after transplantation, the recurrence of IgA nephropathy (IgAN) becomes a relevant cause of graft dysfunction and failure. However, only limited information has been published regarding the related clinical and histological features. In this article, we review studies on recurrent IgAN in the English literature and describe our own clinical experience. The clinical and histological features related to recurrence are still indeterminate, but features associated with graft dysfunction include proteinuria, glomerulosclerosis, mesangial proliferation, glomerular crescents and interstitial fibrosis.
Jeong
Hyeon Joo
HJ
Department of Pathology, Yonsei University College of Medicine, 134 Shinchon- dong, Seodaemun-gu, Seoul 120-752, Korea. jeong10@yumc.yonsei.ac.kr
Huh
Kyu Ha
KH
Kim
Yu Seun
YS
Kim
Soon Il
SI
D005922:Glomerulonephritis, IGA / Q000503:physiopathology* / Q000601:surgery*; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D016030:Kidney Transplantation; D012008:Recurrence; D014184:Transplantation, Homologous