Circadian biology: fibroblast clocks keep ticking.
Real-time cellular imaging of gene expression has revealed that fibroblasts contain a robust, self-sustained and cell-autonomous circadian oscillator, with a range of properties that both overlap and contrast with those of the neural clock of the suprachiasmatic nuclei.
Hastings
Michael H
MH
MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK. mha@mrc-lmb.cam.ac.uk
D000818:Animals; D001683:Biological Clocks / Q000235:genetics / Q000502:physiology*; D002940:Circadian Rhythm / Q000235:genetics / Q000502:physiology*; D005347:Fibroblasts / Q000502:physiology*; D005786:Gene Expression Regulation; D013493:Suprachiasmatic Nucleus / Q000502:physiology