Tendon injury and tendinopathy: healing and repair.
Tendon disorders are frequent and are responsible for substantial morbidity both in sports and in the workplace. Tendinopathy, as opposed to tendinitis or tendinosis, is the best generic descriptive term for the clinical conditions in and around tendons arising from overuse. Tendinopathy is a difficult problem requiring lengthy management, and patients often respond poorly to treatment. Preexisting degeneration has been implicated as a risk factor for acute tendon rupture. Several physical modalities have been developed to treat tendinopathy. There is limited and mixed high-level evidence to support the, albeit common, clinical use of these modalities. Further research and scientific evaluation are required before biological solutions become realistic options.
Sharma
Pankaj
P
Department of Trauma and Orthopaedics, Keele University School of Medicine, Thornburrow Drive, Hartshill, Stoke-on-Trent, Staffordshire, ST4 7QB, United Kingdom.
Maffulli
Nicola
N
D015316:Genetic Therapy; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation; D052256:Tendinopathy / Q000503:physiopathology / Q000601:surgery; D013708:Tendon Injuries / Q000503:physiopathology / Q000601:surgery; D013710:Tendons / Q000033:anatomy & histology / Q000502:physiology; D023822:Tissue Engineering; D014945:Wound Healing