title: Colonic perforation in collagenous colitis: an unusual complication.
abstract: Collagenous colitis is generally regarded as a benign disease with few serious complications. We report two women with collagenous colitis who presented with colonic perforation, one spontaneously and one 7 days after a barium enema, and a review of the literature. Including the present cases, 13 patients with collagenous colitis and colonic perforation have been reported, in two patients spontaneously and in 11 patients after a colonoscopy or barium enema. All were operated on except one patient who recovered after medical treatment. The pathogenesis of this complication is unknown. We propose that there might be a connection between mucosal tears and colonic perforation in collagenous colitis.
authors.affiliation: Department of Medicine, Division of Gastroenterology, Orebro University Hospital, Orebro, Sweden. johan.bohr@orebroll.se
authors.forename: Johan
authors.initials: J
authors.lastname: Bohr
authors.forename: Lars-Göran
authors.initials: LG
authors.lastname: Larsson
authors.forename: Sune
authors.initials: S
authors.lastname: Eriksson
authors.forename: Gunnar
authors.initials: G
authors.lastname: Järnerot
authors.forename: Curt
authors.initials: C
authors.lastname: Tysk
mesh_terms: D001466:Barium Sulfate; D046729:Colitis, Collagenous / Q000150:complications* / Q000473:pathology; D003106:Colon / Q000293:injuries*; D003108:Colonic Diseases / Q000209:etiology / Q000473:pathology; D003287:Contrast Media; D004733:Enema / Q000009:adverse effects; D005260:Female; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged
chemical_list: D003287:Contrast Media; D001466:Barium Sulfate