title: Gama-aminobutyric acid accumulation in Elsholtzia splendens in response to copper toxicity.
abstract: A solution with different Cu supply levels was cultured to investigate gama-aminobutyric acid (GABA) accumulation in Elsholtzia splendens, a native Chinese Cu-tolerant and accumulating plant species. Increasing Cu from 0.25 to 500 micromol/L significantly enhanced levels of GABA and histidine (His), but considerably decreased levels of aspartate (Asp) and glutamate (Glu) in the leaves. The leaf Asp level negatively correlated with leaf Cu level, while leaf GABA level positively correlated with leaf Cu level. The leaf Glu level negatively correlated with leaf GABA level in Elsholtzia splendens. The depletion of leaf Glu may be related to the enhanced synthesis of leaf GABA under Cu stress.
authors.forename: Xiao-e
authors.initials: XE
authors.lastname: Yang
authors.forename: Hong-yun
authors.initials: HY
authors.lastname: Peng
authors.forename: Sheng-ke
authors.initials: SK
authors.lastname: Tian
mesh_terms: D003300:Copper / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D004361:Drug Tolerance / Q000502:physiology*; D005786:Gene Expression Regulation / Q000187:drug effects; D019686:Lamiaceae / Q000187:drug effects* / Q000378:metabolism*; D018515:Plant Leaves / Q000187:drug effects* / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
chemical_list: D005680:gamma-Aminobutyric Acid; D003300:Copper