The chemistry and biology of nitroxyl (HNO): a chemically unique species with novel and important biological activity.
Fukuto
Jon M
JM
Department of Pharmacology, UCLA School of Medicine, CHS, Los Angeles, CA 90095-1735, USA. jfukuto@mednet.ucla.edu
Dutton
Andrew S
AS
Houk
Kendall N
KN
D000426:Alcohol Dehydrogenase / Q000187:drug effects; D000818:Animals; D005978:Glutathione / Q000378:metabolism; D006801:Humans; D018696:Neuroprotective Agents / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D009589:Nitrogen Oxides / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D016194:Receptors, N-Methyl-D-Aspartate / Q000187:drug effects; D015427:Reperfusion Injury / Q000188:drug therapy; D013438:Sulfhydryl Compounds / Q000378:metabolism; D013816:Thermodynamics; D016277:Ventricular Function, Left / Q000187:drug effects
D018696:Neuroprotective Agents; D009589:Nitrogen Oxides; D016194:Receptors, N-Methyl-D-Aspartate; D013438:Sulfhydryl Compounds; D000426:Alcohol Dehydrogenase; D005978:Glutathione; C039900:nitroxyl