[A severe case of nephrotic syndrome].
A 14-year-old girl presented at the Renal Unit with clinical and laboratory pictures of a severe nephrotic syndrome. It was done a kidney biopsy which detected a picture of "minimal change". As the patient had no benefit from the prednisone therapy, she underwent to another biopsy which detected, this time, a Focal Glomerulosclerosis. Despite the immunosuppressive therapy, the renal function deteriorated and, therefore, the patient began dialysis. After a while, the girl received a cadaveric kidney transplantation but the nephrotic syndrome recurred again and the patient went back to chronic dialysis.
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CNR-IBIM, Consiglio Nazionale delle Ricerche Istituto di Bio-Medicina Epidemiologia Clinica e Fisiopatologia, Malattie Renali e dell'Ipertensione Arteriosa, Reggio Calabria. nefrologia@oirmsantanna.piemonte.it
D000293:Adolescent; D005260:Female; D006801:Humans; D009404:Nephrotic Syndrome / Q000175:diagnosis / Q000628:therapy; D012720:Severity of Illness Index