[Studies on the flavonoids in herb from Scutellaria barbata].
OBJECTIVE
To study flavonoids in Scutellaria barbata and elucidate their structures.


METHODS
Compounds were isolated and purified by normal column chromatography, paper thin layer chromatography and Sephadex chromatography. The chemical structures were elucidated by ESI mass and NMR spectra.


RESULTS
Five flavonoids were isolated from S. barbata and identified as apigenin (1), luteolin (2), ethyl-7-O-apigenin-glucuronate (3), apigenin-7-O-beta-glucoside (4), and apigenin-7-O-neohesperidoside (5), in addition to benzyaldehyde (6).


CONCLUSIONS
Flavonoidglycoside (3), (4) and (5) were isolated from S. barbata for the first time.
Wang
Wen-shu
WS
Key Laboratory of Bioorganic and Molecular Engineering, Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
Zhou
Ya-wei
YW
Ye
Yun-hua
YH
Du
Nan
N
D047310:Apigenin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D005965:Glucuronates / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D031363:Scutellaria / Q000737:chemistry*
D005419:Flavonoids; D005965:Glucuronates; C500371:ethyl 7-O-apigenin-glucuronate; C057792:apigetrin; D047310:Apigenin