title: Stille cross-couplings of unactivated secondary alkyl halides using monoorganotin reagents.
abstract: The first catalyst that achieves Stille cross-couplings of secondary (as well as primary) alkyl halides has been developed. The method employs easily handled and inexpensive catalyst components (NiCl2 and 2,2'-bipyridine) and, through the use of monoorganotin reagents, avoids the formation of toxic and difficult-to-remove triorganotin side products.
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
authors.forename: David A
authors.initials: DA
authors.lastname: Powell
authors.forename: Toshihide
authors.initials: T
authors.lastname: Maki
authors.forename: Gregory C
authors.initials: GC
authors.lastname: Fu
mesh_terms: D002384:Catalysis; D006838:Hydrocarbons / Q000138:chemical synthesis*; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D014001:Tin / Q000737:chemistry*
chemical_list: D006838:Hydrocarbons; D006846:Hydrocarbons, Halogenated; D009942:Organometallic Compounds; D014001:Tin