title: Subperiosteal leiomyosarcoma of the tibia.
abstract: Primary leiomyosarcoma of bone is a rare malignant tumor of smooth muscle. We report a case of low-grade subperiosteal primary bone leiomyosarcoma in the tibial diaphysis, which radiologically appeared to be osteoid osteoma. A 35-year-old man presented with a several-year history of a palpable hard nodule in the distal left leg, which had enlarged and become painful over the previous 2 years. Radiographs showed solid periosteal reaction with a well-defined lytic lesion in the posteromedial cortical border of the left tibial diaphysis. Computed tomography demonstrated a small, well-defined lytic lesion, not calcified, in a subperiosteal location, surrounded by solid periosteal bone formation. The lesion was excised en bloc and the histological diagnosis of a low-grade leiomyosarcoma was made. To the best of our knowledge, the surface location of primary bone leiomyosarcoma has not been previously described in the literature.
authors.affiliation: Department of Radiology, Hospital Universitari de Bellvitge, Barcelona, Spain.
authors.forename: J A
authors.initials: JA
authors.lastname: Narváez
authors.forename: E
authors.initials: E
authors.lastname: De Lama
authors.forename: F
authors.initials: F
authors.lastname: Portabella
authors.forename: R
authors.initials: R
authors.lastname: Ortega
authors.forename: E
authors.initials: E
authors.lastname: Condom
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D018483:Diaphyses / Q000000981:diagnostic imaging; D005500:Follow-Up Studies; D006801:Humans; D007890:Leiomyosarcoma / Q000000981:diagnostic imaging*; D008297:Male; D010017:Osteoma, Osteoid / Q000175:diagnosis; D010521:Periosteum / Q000000981:diagnostic imaging; D013977:Tibia / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed