title: Library preparation of derivatives of 1,4,10,13-tetraoxa-7,16-diaza-cycloctadecane and their fluorescence behavior for signaling purposes.
abstract: In the present work, we report the library preparation on solid supports of 20 derivatives of 1,4,10,13-tetraoxa-7,15-diaza-cycloctadecane 1(a-e)(w,x,y,z) carrying a fluorescent dansyl group. The sensing fluorescence behavior of these materials toward alkali and alkali earth metal ions was studied by packing the beads into a conventional flow-through cell in a FIA (flow injection analysis) approach. The fluorescence emission of these materials' responses shows a fluorescence increase to Li+, Na+, K+, NH4+, Ca2+, and Mg2+ with maximum sensitivity for Mg2+ over the rest of the ions. The analytical potential of these materials is outlined, and the sensing response mechanism, based on a photoinduced electron-transfer process, is proposed.
authors.affiliation: Graduate Center & Research, Technological Institute of Tijuana, P.O. 1166, Tijuana, 22000 B.C. México. irivero@tectijuana.mx
authors.forename: I A
authors.initials: IA
authors.lastname: Rivero
authors.forename: T
authors.initials: T
authors.lastname: Gonzalez
authors.forename: G
authors.initials: G
authors.lastname: Pina-Luis
authors.forename: M E
authors.initials: ME
authors.lastname: Diaz-Garcia
mesh_terms: D000473:Alkanes / Q000032:analysis* / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D043844:Crown Ethers / Q000737:chemistry; D017022:Flow Injection Analysis; D005453:Fluorescence; D006571:Heterocyclic Compounds / Q000032:analysis* / Q000737:chemistry*; D007477:Ions / Q000737:chemistry; D008670:Metals / Q000737:chemistry; D015394:Molecular Structure; D013050:Spectrometry, Fluorescence; D013816:Thermodynamics
chemical_list: C507685:1,4,10,13-tetraoxa-7,16-diaza-cycloctadecane; D000473:Alkanes; D043844:Crown Ethers; D006571:Heterocyclic Compounds; D007477:Ions; D008670:Metals; C022883:octadecane