[Study on the effects of two kinds of cactus polysaccharide on erythrocyte membrane protein and fluidity of the lipid in S180 mice].
OBJECTIVE
To study the effects of two kinds of cactus polysaccharide on Band 3 protein, cross-linking protein and lipid fluidity of erythrocyte membrane in S180 mice.


METHODS
The membrane protein content was analysed by SDS-PAGE. Lipid fluidity was measured by Skinitzky method.


RESULTS
The two kinds of cactus polysaccharide increased the content of Band 3 protein and decreased the content of cross-linking protein, raised the lipid fluidity. While the effect of median dose group of medical cactus polysaccharide is very remarkable (P < 0.01), the effect of high dose group of edible cactus polysaccharide is very remarkable (P < 0.01).


CONCLUSIONS
By improving the erythrocyte membrane function of tumor-mice, they enhanced the immune function, which may be one of anti-tumor mechanisms.
Ji
Yu-bin
YB
Postdoctal Research of the Institute of Materia Medica, Harbin University of Commerce, Harbin 150076, China.
Ji
Chen-feng
CF
Zou
Xiang
X
Gao
Shi-yong
SY
D000818:Animals; D001457:Anion Exchange Protein 1, Erythrocyte / Q000378:metabolism*; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004910:Erythrocyte Membrane / Q000378:metabolism* / Q000502:physiology; D008297:Male; D008560:Membrane Fluidity / Q000187:drug effects; D051379:Mice; D029747:Opuntia / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D011134:Polysaccharides / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D012510:Sarcoma 180 / Q000378:metabolism*
D001457:Anion Exchange Protein 1, Erythrocyte; D000972:Antineoplastic Agents, Phytogenic; D011134:Polysaccharides