title: Fournier's gangrene in neonates and infants.
abstract: BACKGROUND
  Fournier's gangrene is uncommon in childhood and little is known about the disease in this age group.
  
  
  METHODS
  A retrospective review was carried out of neonates and infants treated for Fournier's gangrene over a period of 16 years.
  
  
  RESULTS
  Twelve neonates and infants aged 5 days-3 months (median 3 weeks) were treated in our hospital. The precipitating cause was omphalitis in 7 babies, strangulated inguinal hernia in 2 and in 3 babies there was no identifiable cause. Gram-negative bacteria were cultured in 3 patients, but in most the culture was sterile. Treatment consisted of debridement of devitalised tissue and administration of broad-spectrum antibiotics. Primary closure was achieved in 1 baby and secondary closure in 2 others. In 7 babies the wound contracted rapidly and healed. There was no mortality.
  
  
  CONCLUSIONS
  Fournier's gangrene in neonates and infants in our environment is largely preventable. Early debridement and appropriate antibiotics give good results.
authors.affiliation: Paediatric Surgery Unit, Department of Surgery, Ahmadu Bello University Teaching Hospital, PO Box 76, 810 001 Zaria, Nigeria. ssrs.njsr@skannet.com
authors.forename: E A
authors.initials: EA
authors.lastname: Ameh
authors.forename: M M
authors.initials: MM
authors.lastname: Dauda
authors.forename: L
authors.initials: L
authors.lastname: Sabiu
authors.forename: P M
authors.initials: PM
authors.lastname: Mshelbwala
authors.forename: H N
authors.initials: HN
authors.lastname: Mbibu
authors.forename: P T
authors.initials: PT
authors.lastname: Nmadu
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003646:Debridement; D018934:Fournier Gangrene / Q000601:surgery / Q000628:therapy*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012189:Retrospective Studies
chemical_list: D000900:Anti-Bacterial Agents