Pediatric hypereosinophilic syndrome (HES) differs from adult HES.
The idiopathic hypereosinophilic syndrome (HES) developed in a 15-year-old boy who presented with colitis, cough, rash, and hepatitis. Molecular analysis failed to demonstrate the Fip1-like1-Platelet Derived Growth Factor Receptor alpha chain (FIP1L1-PDGFRA) mutation described in adult patients with HES. There are significant clinical differences between the pediatric and adult presentations of HES.
Katz
Hary T
HT
Department of Pulmonary Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Haque
S Jaharul
SJ
Hsieh
Fred H
FH
D000293:Adolescent; D000328:Adult; D003092:Colitis / Q000209:etiology*; D003371:Cough / Q000209:etiology*; D005076:Exanthema / Q000209:etiology*; D006505:Hepatitis / Q000209:etiology*; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008297:Male; D016896:Treatment Outcome