[Genetic polymorphisms of STR loci THO1, TPOX, CSF1PO in Guizhou Han population].
To understand the genetic polymorphism at THO1, TPOX, CSF1PO STR loci for Han population in Guizhou Province, and construct a preliminary database, EDTA-blood specimens were collected from the 110 unrelated individuals in Han population from Guizhou. The DNA samples were extracted with Chelex method and amplified by multiplex polymerase chain reaction. The PAGE was used to type the PCR products. The allele frequencies were compared with other Han populations. The genotype distributions of THO1, TPOX and CSF1PO were in accordance with Hardy-Weinberg equilibrium. The combined PD and PE were 0.9986 and 0.832 respectively. All of the three loci in this study provide useful marker for forensic paternity test and individual identification.
Zhou
Qiang
Q
Family Planning Institute of Guizhou, Guiyang 550004, China. gyzq@vip.sina.com
Wu
Si-Kun
SK
Yu
Fang
F
He
Rong-Yue
RY
D000483:Alleles; D002681:China; D002880:Chromosomes, Human, Pair 11 / Q000235:genetics; D002889:Chromosomes, Human, Pair 2 / Q000235:genetics; D002895:Chromosomes, Human, Pair 5 / Q000235:genetics; D005554:Forensic Medicine; D005787:Gene Frequency; D005819:Genetic Markers / Q000235:genetics*; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D010334:Paternity; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences / Q000235:genetics*
D005819:Genetic Markers