MRI findings in Kallmann syndrome.
Kallmann syndrome (KS) is a neuronal migration disorder characterised by hypogonadotrophic hypogonadism and anosmia or hyposmia. Five patients with clinical findings suggestive of KS were evaluated with MRI. All patients had abnormalities of olfactory system. Olfactory bulbs were absent in all patients. Olfactory sulci were absent in 3 patients and hypoplastic in 2 patients. Anterior pituitary was hypoplastic in two patients. The MRI findings in KS are characteristic and MRI is a useful adjunct to the diagnosis of KS.
Madan
R
R
Department of Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Rae Bareli Road, Lucknow, India.
Sawlani
Vijay
V
Gupta
Sushil
S
Phadke
R V
RV
D000328:Adult; D006801:Humans; D017436:Kallmann Syndrome / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D009830:Olfactory Bulb / Q000473:pathology; D009833:Olfactory Pathways / Q000473:pathology; D010903:Pituitary Gland, Anterior / Q000473:pathology