Rationale for the daily use of a dentifrice containing triclosan in the maintenance of oral health.
This paper provides an overview and summary of the data that demonstrate the effectiveness of a dentifrice containing triclosan/copolymer/fluoride in significantly reducing plaque, calculus, gingivitis, and the onset and progression of periodontitis. The caries-preventive benefit of the triclosan/copolymer/fluoride dentifrice was at least as good as that of a fluoride dentifrice. No evidence of bacterial resistance or the development of pathogenic or opportunistic bacteria was observed.
DeVizio
William
W
The Colgate-Palmolive Company, Technology Center, Piscataway, New Jersey, USA.
Davies
Robin
R
D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D002327:Cariostatic Agents / Q000627:therapeutic use; D045424:Complex Mixtures; D003728:Dental Calculus / Q000517:prevention & control*; D003773:Dental Plaque / Q000517:prevention & control*; D003802:Dentifrices / Q000627:therapeutic use*; D005459:Fluorides; D005891:Gingivitis / Q000517:prevention & control*; D006801:Humans; D010518:Periodontitis / Q000517:prevention & control*; D012824:Silicic Acid; D014100:Toothpastes; D014260:Triclosan
D000891:Anti-Infective Agents, Local; D002327:Cariostatic Agents; D045424:Complex Mixtures; D003802:Dentifrices; D014100:Toothpastes; C546060:hydrated silica gel-based toothpaste; D012824:Silicic Acid; D014260:Triclosan; D005459:Fluorides