[Lipids and homocysteine level in juvenile idiopathic arthritis].
We investigated serum levels of lipids (total cholesterol, HDL-cholesterol, LDL-cholesterol, triglicerides), homocysteine, C-reactive protein (CRP) in 25 children with juvenile idiopathic arthritis (JIA) and 15 healthy control. We found statistically significant increase of total cholesterol, LDL-cholesterol, triglicerides (p<0.05) and decreased of HDL-cholesterol (p<0.05) in JIA patients compare to control group. Homocysteine correlated significantly with total cholesterol (r=0.47; p<0.05) and with LDL-cholesterol (r=0.53; p<0.05). In JIA children we found adverse lipids profile and increase of homocysteine level which may lead to early atherosclerosis.
Urban
Mirosława
M
I Klinika Chorób Dzieci AM w Białymstoku. klchdz2@cksr.ac.bialystok.pl
Pietrewicz
Edyta
E
Górska
Anna
A
Głowińska
Barbara
B
D000293:Adolescent; D000328:Adult; D001171:Arthritis, Juvenile / Q000097:blood*; D002097:C-Reactive Protein / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D008297:Male; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D006710:Homocysteine; D002097:C-Reactive Protein; D002784:Cholesterol