title: Tissue response to poly-L-lactide acid-polyglycolic acid absorbable screws in autogenous bone grafts: a histologic morphological analysis.
abstract: OBJECTIVE
  To evaluate the local bone condition of autogenous chin grafts in contact with resorbable polymers fixation devices.
  
  
  METHODS
  Seven patients presenting severe maxillary and mandibular atrophy underwent alveolar ridge reconstruction with autogenous chin grafts fixed with conventional metallic screws, who received poly L-lactide acid-polyglycolic acid and titanium test screws for histological evaluation after 4 months of implantation.
  
  
  RESULTS
  Viable bone tissue could be seen in the specimens related to titanium test screws, with no signs of bone resorption or inflammation. A thick layer of fibrous connective tissue was observed between the resorbable test screws and bone tissue, which presented a few areas of resorption.
  
  
  CONCLUSIONS
  There are no contraindications of both materials for use as fixation devices in autogenous bone grafts. However, care must be taken when using absorbable screws in a period of 4 months, which can interfere with the sequence of the treatment with endosseous dental implants.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Universidade do Sagrado Coração, Rua Rio Branco 19-79, Altos da Cidade, 17014-480 Bauru/São Paulo, Brazil.
authors.forename: Mariza Akemi
authors.initials: MA
authors.lastname: Matsumoto
authors.forename: Hugo Nary
authors.initials: HN
authors.lastname: Filho
authors.forename: Luís Eduardo Marques
authors.initials: LE
authors.lastname: Padovan
authors.forename: Roberto Yoshio
authors.initials: RY
authors.lastname: Kawakami
authors.forename: Luís Antônio
authors.initials: LA
authors.lastname: De Assis Taveira
mesh_terms: D020341:Absorbable Implants / Q000009:adverse effects*; D000328:Adult; D000540:Alveolar Ridge Augmentation / Q000379:methods; D001672:Biocompatible Materials / Q000009:adverse effects*; D001863:Bone Screws / Q000009:adverse effects*; D016025:Bone Transplantation; D003758:Dental Implantation, Endosseous; D005260:Female; D005549:Foreign-Body Reaction / Q000209:etiology*; D006801:Humans; D019344:Lactic Acid / Q000009:adverse effects*; D008297:Male; D008422:Materials Testing; D008875:Middle Aged; D016348:Osseointegration; D011100:Polyglycolic Acid / Q000009:adverse effects*; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011108:Polymers / Q000009:adverse effects*; D014025:Titanium
chemical_list: D001672:Biocompatible Materials; D011108:Polymers; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid; D014025:Titanium