[Polymorphism of the central region of D-loop of mitochondrial DNA and personality identification by forensic medicine methods].
Polymorphism of mDNA D-loop central region (CR), positions 16366-0072) was studied versus hypervariable sections (HVS1), positions 16024-16365, and HVS2, positions 00073-00340, for a sample of 71 residents of the Russian Federation. Ten polymorphic positions with 56 nucleotide substitutions, 55 of which are transitions, were detect in the CR section; no insertions or deletions were found there. It was proven as possible to use the mDNA CR locus as an additional identification marker in the forensic-expert of the mDNA control region. The probability of random coincidence (RC) of haplotypes in joint typing of HVS1, HVS2 and CR made 0.0208, which is 1.4-fold less versus the same parameter for haplotypes HVS1/HVS2 (RC = 0.0284).
Kornienko
I V
IV
Vodolazhskiĭ
D I
DI
Afanas'eva
G V
GV
Ivanov
P L
PL
D001483:Base Sequence; D016172:DNA Fingerprinting / Q000379:methods*; D004272:DNA, Mitochondrial / Q000235:genetics* / Q000302:isolation & purification; D005554:Forensic Medicine; D006801:Humans; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic
D004272:DNA, Mitochondrial