title: Seroprevalence of Helicobacter pylori infection in urban and rural Vietnam.
abstract: Helicobacter pylori-associated diseases, such as peptic ulcer and gastric cancer, are common in Vietnam, but the prevalence of the infection is largely unknown. A validated enzyme-linked immunosorbent assay was used for seroepidemiology with 971 samples from the general population, ages 0 to 88 years, with 546 samples from an urban population (Hanoi), and with 425 samples from a poor, rural province (Hatay). The overall seroprevalence of the infection was 746 per 1,000, with a prevalence of 788 per 1,000 in Hanoi and 692 per 1,000 in Hatay (P=0.0007). The risk for infection in the rural area of Hatay was 40% lower than in the urban population of Hanoi, with the odds ratio being 0.59 (95% confidence interval, 0.43 to 0.81). The study shows that the prevalence of H. pylori infection is high in Vietnam and especially high in a large urban area, such as the city of Hanoi.
authors.affiliation: Department of Clinical Microbiology, Karolinska Hospital, S-171 76 Stockholm, Sweden.
authors.forename: Thi Thu Ha
authors.initials: TT
authors.lastname: Hoang
authors.forename: Carina
authors.initials: C
authors.lastname: Bengtsson
authors.forename: Dac Cam
authors.initials: DC
authors.lastname: Phung
authors.forename: Mikael
authors.initials: M
authors.lastname: Sörberg
authors.forename: Marta
authors.initials: M
authors.lastname: Granström
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016481:Helicobacter Infections / Q000097:blood* / Q000453:epidemiology*; D016480:Helicobacter pylori; D006801:Humans; D015151:Immunoblotting; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012424:Rural Population; D016036:Seroepidemiologic Studies; D014505:Urban Population; D014744:Vietnam / Q000453:epidemiology