Notochord morphogenesis: a prickly subject for ascidians.
Orchestrated cell movements marshalled by proper cell polarity in the developing body axes are fundamental to the elongation of the notochord during chordate embryogenesis. A recent study shows that, in ascidians, the planar cell polarity gene prickle regulates sequential establishment of cell polarity during two phases of notochord morphogenesis.
Tada
Masazumi
M
Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK. m.tada@ucl.ac.uk
D000818:Animals; D019521:Body Patterning; D016764:Cell Polarity / Q000235:genetics / Q000502:physiology; D004268:DNA-Binding Proteins / Q000235:genetics; D018507:Gene Expression Regulation, Developmental; D009024:Morphogenesis; D009672:Notochord / Q000196:embryology; D010641:Phenotype; D019170:Somites / Q000502:physiology; D014561:Urochordata / Q000196:embryology
D004268:DNA-Binding Proteins