Two new alkaloids from the rhizome of Polygonatum sibiricum.
Two new alkaloids named polygonatine A (1) and polygonatine B (2) have been isolated from the rhizome of Polygonatum sibiricum Redoute (Liliaceae). By spectral data (IR, UV, MS, 1D and 2D NMR) and chemical evidence, their structures were elucidated as 3-hydroxymethyl-5,6,7,8-tetrahydroindolizin-8-one (1) and 3-ethoxymethyl-5,6,7,8-tetrahydroindolizin-8-one (2).
Sun
Long-Ru
LR
School of Pharmacy, Shandong University, 44 West Wenhua Road, Jinan 250012, China. sunlr@sdu.edu.cn
Li
Xian
X
Wang
Su-Xian
SX
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D002855:Chromatography, Thin Layer; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D007212:Indolizines / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D031384:Polygonatum / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000470:Alkaloids; D004365:Drugs, Chinese Herbal; D007212:Indolizines