title: Effects of brain-lesion size and location on temporal-order judgment.
abstract: We assessed the effect of size and localization of a brain lesion on patients' abilities to perceive the temporal order of two acoustic stimuli. In those patients who had performed with impaired order thresholds, local overlaps of lesions as analyzed with CT were found in specific left-hemispheric regions of the temporal and parietal lobe. However, a moderate association of lesion size and temporal-order threshold was found among all brain-injured patients (n = 30), a correlation that was most pronounced in patients with right-hemispheric lesions. This non-specific effect of lesion size has to be discussed critically with respect to behavioral findings of an association between temporal-processing abilities and language competence.
authors.affiliation: Generation Research Program Bad Tölz, Human Science Center, Ludwig-Maximilian University of Munich, Prof.-Max-Lange-Platz 11, 83646 Bad Tölz, Germany. wittmann@grp.hwz.uni-muenchen.de
authors.forename: Marc
authors.initials: M
authors.lastname: Wittmann
authors.forename: Ariane
authors.initials: A
authors.lastname: Burtscher
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Fries
authors.forename: Nicole
authors.initials: N
authors.lastname: von Steinbüchel
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods; D000328:Adult; D000368:Aged; D001307:Auditory Perception / Q000502:physiology*; D001930:Brain Injuries / Q000473:pathology / Q000503:physiopathology*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007600:Judgment / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D015898:Tomography Scanners, X-Ray Computed