title: Botulinum toxin type A in the management of masseter muscle hypertrophy.
abstract: OBJECTIVE
  We sought to evaluate the response of 6 patients with masseter muscle hypertrophy to botulinum toxin type A therapy.
  
  
  METHODS
  Six patients with unilateral or bilateral masseter muscle hypertrophy received intramuscular injection of the botulinum toxin type A. The functional and cosmetic results were evaluated as well as recurrence.
  
  
  RESULTS
  In all patients, satisfactory regression of the masseter muscle hypertrophy occurred and mild muscular pain was relieved. Recurrence was observed in 2 cases.
  
  
  CONCLUSIONS
  The use of botulinum toxin type A in masseter muscle hypertrophy therapy was shown to be a successful and safe treatment method. This procedure to control parafunctional activities involving the masticatory muscles of patients appears to be useful.
authors.affiliation: Department of Oral Surgery and Oral Pathology, School of Dentistry, University of Minas Gerais, Belo Horizonte, Brazil. wagnercastro@ufmg.br
authors.forename: Wagner Henriques
authors.initials: WH
authors.lastname: Castro
authors.forename: Rodrigo Santiago
authors.initials: RS
authors.lastname: Gomez
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Da Silva Oliveira
authors.forename: Mariela Dutra Gontijo
authors.initials: MD
authors.lastname: Moura
authors.forename: Ricardo Santiago
authors.initials: RS
authors.lastname: Gomez
mesh_terms: D000293:Adolescent; D000328:Adult; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000188:drug therapy; D007273:Injections, Intramuscular; D008297:Male; D008406:Masseter Muscle; D009135:Muscular Diseases / Q000188:drug therapy*; D009465:Neuromuscular Agents / Q000008:administration & dosage*; D012008:Recurrence; D016896:Treatment Outcome
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A