title: [The effect of heat stimulation and mechanical stress (massage) of salivary glands on the secretory parameters of salivary Hsp70. A pilot study].
abstract: The presence of Hsp70 in human whole saliva was demonstrated in the authors' previous study. In the recent study the authors investigated, whether repeated, short-term heat and mechanical stimulation of the salivary glands can specifically modify the salivary Hsp70 concentration in the human whole saliva. Some other basic secretory parameters, like salivary secretion rate, total protein concentration and amylase activity of the whole saliva were also measured. Both kind of stimulation increased the secretory rate significantly (p < or = 0.05), during stimulation, but it decreased to control level in resting phases. Hsp70 concentration increased after the first stimulation in the case of mechanical stress and after the second stimulation in the case of heat stimulation. In contrast, a significant (p < or = 0.05) confluent increase of total protein concentration and amylase activity occurred after the first stimulation in the case of heat stimulation and after the second stimulation in the case of mechanical stress. Further investigations are needed to evaluate the durability and clinical importance of salivary changes following local heat and massage stimulation.
authors.affiliation: Semmelweis Egyetem, Fogpótlástani Klinika, Budapest.
authors.forename: László
authors.initials: L
authors.lastname: Féjerdy
authors.forename: Zsuzsanna
authors.initials: Z
authors.lastname: Tóth
authors.forename: Borbála
authors.initials: B
authors.lastname: Kaán
authors.forename: Károly
authors.initials: K
authors.lastname: Fábián Tibor
authors.forename: Péter
authors.initials: P
authors.lastname: Csermely
authors.forename: Pál
authors.initials: P
authors.lastname: Fejérdy
mesh_terms: D018840:HSP70 Heat-Shock Proteins / Q000378:metabolism*; D006358:Hot Temperature; D006801:Humans; D008405:Massage; D018832:Molecular Chaperones / Q000378:metabolism; D012463:Saliva / Q000378:metabolism*; D012469:Salivary Glands / Q000378:metabolism*; D012636:Secretory Rate; D013314:Stress, Mechanical
chemical_list: D018840:HSP70 Heat-Shock Proteins; D018832:Molecular Chaperones