[miRNA: a new regulator of gene expression].
Plant and animal genomes contain an abundance of small genes that produce RNAs of about 22 nucleotides in length, which was dubbed as microRNAs. These newly found endogenous RNAs may participate in a wide range of genetic regulatory pathways and play an important role in the development. This paper is focused on the finding of the microRNAs, its mechanism and function, as well as the methods of research.
Li
Cheng-Mei
CM
Biology of Department, Capital Normal University, Beijing 100037, China. suansuandemeizi@sohu.com
Zheng
Ji-Gang
JG
Du
Gui-Sen
GS
D000818:Animals; D017360:Arabidopsis / Q000235:genetics; D017173:Caenorhabditis elegans / Q000235:genetics*; D004330:Drosophila / Q000235:genetics; D005786:Gene Expression Regulation; D006801:Humans; D035683:MicroRNAs / Q000235:genetics* / Q000302:isolation & purification; D013768:Tetrahymena / Q000235:genetics
D035683:MicroRNAs; C474488:let-7 microRNA, C elegans; C452194:lin-4 microRNA, C elegans