Confirmation and prevention of targeted toxicity by a recombinant fusion toxin.
Kreitman
Robert J
RJ
Clinical Immunotherapy Section, Laboratory of Molecular Biology, Centers for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892-4255, USA. kreitmar@mail.nih.gov
D000818:Animals; D004167:Diphtheria Toxin / Q000633:toxicity*; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000633:toxicity*; D006801:Humans; D007728:Kupffer Cells / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D009369:Neoplasms / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control*; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism / Q000627:therapeutic use*
D004167:Diphtheria Toxin; D011993:Recombinant Fusion Proteins; D016178:Granulocyte-Macrophage Colony-Stimulating Factor