Nitrogenous educts through oxidative amidation of phenols: the bimolecular reaction.
[Reaction: see text] The elusive oxidative amidation of phenols to 4-aza-substituted dienones in the bimolecular mode may be achieved by treatment with iodobenzene diacetate ("DIB") in a mixture of hexafluoro-2-propanol and acetonitrile.
Canesi
Sylvain
S
Laboratoire de Synthèse et Méthodologie Organiques, CNRS UMR 5181, Université Claude Bernard Lyon 1 and Ecole Supérieure de Chimie, Physique et Electronique de Lyon, 43, Bd du 11 Novembre 1918, 69622 Villeurbanne, France.
Bouchu
Denis
D
Ciufolini
Marco A
MA
D000577:Amides / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*; D010084:Oxidation-Reduction; D010636:Phenols / Q000737:chemistry* / Q000378:metabolism
D000577:Amides; D010636:Phenols; D009584:Nitrogen