title: Synthesis of oxychelerythrine using lithiated toluamide-benzonitrile cycloaddition.
abstract: Oxychelerythrine, benzo[c]phenanthridine alkaloid, was synthesized from easily available starting toluamide 5 and benzonitrile 6 using toluamide-benzonitrile cycloaddition reaction in 6 steps.
authors.affiliation: College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Kwangju, Korea.
authors.forename: Thanh Nguyen
authors.initials: TN
authors.lastname: Le
authors.forename: Won-Jea
authors.initials: WJ
authors.lastname: Cho
mesh_terms: D000470:Alkaloids; D053119:Benzophenanthridines; D009570:Nitriles / Q000138:chemical synthesis*; D010617:Phenanthridines / Q000138:chemical synthesis*; D014050:Toluene / Q000138:chemical synthesis*
chemical_list: D000470:Alkaloids; D053119:Benzophenanthridines; D009570:Nitriles; D010617:Phenanthridines; D014050:Toluene; C014356:benzonitrile; C016299:chelerythrine