title: [Detection of differentially expressed genes in hepatocellularcarcinoma cells SMMC-7721 treated with Typhonium giganteum extract by mRNA differential display].
abstract: OBJECTIVE
  To screen and identify the differentially expressed genes in hepatocellular carcinoma cells SMMC-7721 responsing to the aqueous extract from dried powdered rhizomes of Typhonium giganteum (AEoTGE).
  
  
  METHODS
  The response of hepatocellular carcinoma cells SMMC-7721 to AEoTGE was explored with the technique of mRNA differential display.
  
  
  RESULTS
  After hepatocarcinoma cells SMMC-7721 were treated by AEoTGE for 36 hours, 1 gene expression was upgrade and 1 gene expression was downgrade induced by AEoTGE.
  
  
  CONCLUSIONS
  The research has provided important clues for the molecular mechanism of how hepatocarcinoma cells responseing to T. giganteum.
authors.affiliation: Molecular Cytogenetics Lab, Nankai University, Tianjin 300071, China.
authors.forename: Shun-qi
authors.initials: SQ
authors.lastname: Wang
authors.forename: Hong
authors.initials: H
authors.lastname: Ni
authors.forename: Hua
authors.initials: H
authors.lastname: Cheng
authors.forename: Guang-liang
authors.initials: GL
authors.lastname: Wang
authors.forename: Tong-shun
authors.initials: TS
authors.lastname: Wang
authors.forename: Li
authors.initials: L
authors.lastname: Chen
mesh_terms: D029064:Araceae / Q000737:chemistry; D006528:Carcinoma, Hepatocellular / Q000235:genetics* / Q000473:pathology; D045744:Cell Line, Tumor; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D020869:Gene Expression Profiling; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects; D006801:Humans; D008113:Liver Neoplasms / Q000235:genetics* / Q000473:pathology; D010946:Plants, Medicinal / Q000737:chemistry; D012334:RNA, Neoplasm / Q000235:genetics; D027343:Rhizome / Q000737:chemistry
chemical_list: D004365:Drugs, Chinese Herbal; D012334:RNA, Neoplasm