[Studies on chemical constituents in fruits of Tibetan medicine Phyllanthus emblica].
OBJECTIVE
To investigate the chemical constituents of Tibetan medicine Phyllanthus emblica.


METHODS
Various chromatographic techniques were employed for isolation and purification of the constituents, and the structures were elucidated by chemical and spectral analyses.


RESULTS
11 compounds were isolated and identified as gallic acid (I), ellagic acid (II), 1-O-galloyl-beta-D-glucose (III), 3,6-di-O-galloyl-D-glucose (IV), chebulinic acid (V), quercetin (VI), chebulagic acid (VII), corilagin (VIII), 3-ethylgallic acid (3-ethoxy-4,5-dihydroxy-benzoic acid, IX), isostrictiniin (X), 1,6-di-O-galloyl-beta-D-glucose (XI).


CONCLUSIONS
3-Ethylgallic acid (3-ethoxy-4,5-dihydroxy-benzoic acid) is a novel compound, and isostrictiniin was found from P. emblica for the first time.
Zhang
Lan-zhen
LZ
School of Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100102, China.
Zhao
Wen-hua
WH
Guo
Ya-jian
YJ
Tu
Guang-zhong
GZ
Lin
Shu
S
Xin
Lin-guang
LG
D004610:Ellagic Acid / Q000737:chemistry / Q000302:isolation & purification; D005638:Fruit / Q000737:chemistry; D005707:Gallic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D029842:Phyllanthus emblica / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D018609:Tibet
D004610:Ellagic Acid; D005707:Gallic Acid; C025525:3-O-methylgallic acid