[Hydrogels: properties and application in the technology of drug form. II. Possibilities of use of hydrogels as active substance carriers].
In first unit of running was described the properties, method the obtention and kinds sensitive on factors such how the temperature, pH, the electrolytes, the chosen substances, light, of hydrogels and hydrogel delivery systems. The following study is a review of literature related to application of hydrogel as healing substances carriers, possibility of application of hydrogels in oral, applied on skin and the rectal, vaginal systems of release, applied on nasal as well as passed to eyes and parenteral. The utilization the hydrogels in construction the new systems of release the substance allows to remain the aspect ratio time of substance at the application place, the obtainment of prolonged release the medicine, by parallel of applied dose and the system undesirable effects. The hydrogels on the basis of were received the form of medicine about controlled release the substance, bioadhesive drug carriers as well targetable devices of therapeutic agents.
Pluta
Janusz
J
Zakład Farmacji Aptecznej, Akademii Medycznej we Wrocławiu.
Karolewicz
Bozena
B
D000279:Administration, Cutaneous; D000281:Administration, Intranasal; D000282:Administration, Intravaginal; D000284:Administration, Oral; D000285:Administration, Rectal; D001458:Bandages; D001682:Biological Availability; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D006801:Humans; D020100:Hydrogels / Q000008:administration & dosage* / Q000737:chemistry*; D007263:Infusions, Parenteral / Q000379:methods; D009883:Ophthalmic Solutions / Q000008:administration & dosage / Q000493:pharmacokinetics
D003692:Delayed-Action Preparations; D004337:Drug Carriers; D020100:Hydrogels; D009883:Ophthalmic Solutions