The utility of routine trauma laboratories in pediatric trauma resuscitations.
BACKGROUND
Because of the difficulties in evaluating injured children, screening blood tests are recommended.


METHODS
Resuscitation blood tests (complete blood count, chem12, coagulation panel, urinalysis) were reviewed for abnormality frequency, injury correlation, managements, and outcome.


RESULTS
Panels were obtained on 240 children (age < 16 years) meeting trauma system criteria. Abnormalities were identified as follows: white blood cell/hematocrit/platelets (41%, 27%, 1%), Na/K/Cl/CO(2) (3%, 30%, 23%, 14%), blood ureal nitrogen/creatinine (6%, 0%), prothrombin time/international normalized ratio/partial thromboplastin time (22%, 16%, 6%), aspartate aminotransferase/alanine transferase (43%, 35%), amylase (2%), glucose (77%), and urinalysis (31%). Organ-specific chemistries predicted injury poorly. Transaminasemia correlated with liver injury when levels exceeded 400 U/L. Two children (1%) with hyperamylasemia had abdominal injuries. Coagulation abnormalities correlated with intracranial injury (43%) and Glasgow Coma Scale (GCS 3 to 8; 56%, GCS 9 to 14; 20%, GCS 15; 14%, P <0.05). Only 25 (10%) had interventions for test abnormalities (11 transfusions, 8 fresh frozen plasma, 3 tests repeated, 3 KCl).


CONCLUSIONS
Routine laboratory panels are little value in the management of injured children.
Keller
Martin S
MS
Department of Pediatric Surgery, Cardinal Glennon Children's Hospital, 1465 South Grand Boulevard, St. Louis, MO 63104, USA. Kellerms@slu.edu
Coln
C Eric
CE
Trimble
Jennifer A
JA
Green
M Christine
MC
Weber
Thomas R
TR
D000180:Acrylic Resins; D000293:Adolescent; D001774:Blood Chemical Analysis; D001780:Blood Coagulation Tests; D002648:Child; D002675:Child, Preschool; D019411:Clinical Laboratory Techniques / Q000706:statistics & numerical data; D003422:Critical Care / Q000379:methods; D003955:Diagnostic Tests, Routine / Q000379:methods / Q000706:statistics & numerical data*; D005260:Female; D005500:Follow-Up Studies; D015600:Glasgow Coma Scale; D019538:Health Care Surveys; D006801:Humans; D007223:Infant; D015601:Injury Severity Score; D007677:Kidney Function Tests; D008111:Liver Function Tests; D008297:Male; D009104:Multiple Trauma / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D012151:Resuscitation / Q000379:methods* / Q000401:mortality; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D016019:Survival Analysis; D014193:Trauma Centers; D016896:Treatment Outcome; D016482:Urinalysis; D014947:Wounds and Injuries / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy*
D000180:Acrylic Resins; C060386:Triad resin