title: [The changes and relation among platelet function, plasma heparin and anti-coagulation-III: activity in patients with hemorrhagic fever with renal syndrome].
abstract: Blood platelet count (BPC), platelet adhesive rate (PAdT), platelet aggregate rate (PAgT), plasma heparin and anti-coagulation-III: activity (AT-III: alpha) were determined in 55 cases with hemorrhagic fever with renal syndrome (HFRS). In these patients, decreased BPC, defect PAdT, PAgT, increased plasma heparin as well as decreased AT-III: a were found, moreover, these changes were much notable in patients with severe type. A positive correlation existed between plasma heparin and BPC, PAdT, PAgT in cases with 80% AT-III: alpha or above (r values were -0.4344, -.7157 and -0.5547 respectly, p<0.01). The results suggested that plasma heparin may be one of factors resulting in decreased BPC and defect platelet function in HFRS patients with 80% AT-III: alpha or above.
authors.affiliation: The Affiliated Hospital of Xuzhou Medical College, Jiangsu 221002.
authors.forename: L
authors.initials: L
authors.lastname: Wei
authors.forename: X
authors.initials: X
authors.lastname: Pan
authors.forename: Y
authors.initials: Y
authors.lastname: Yu
authors.forename: Q
authors.initials: Q
authors.lastname: Lu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000990:Antithrombin III / Q000378:metabolism*; D001792:Blood Platelets / Q000378:metabolism* / Q000502:physiology*; D005260:Female; D006480:Hemorrhagic Fever with Renal Syndrome / Q000097:blood*; D006493:Heparin / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000502:physiology*; D010976:Platelet Count; D055815:Young Adult
chemical_list: D000990:Antithrombin III; D006493:Heparin