title: Acanthovagasteroids A-D, four new 19-hydroxylated steroids from the South China Sea gorgonian Acanthogorgia vagae Aurivillius.
abstract: Four new steroids, acanthovagasteroids A-D (1-4), along with two known analogues (5, 6), were isolated from the gorgonian Acanthogorgia vagae Aurivillius from the South China Sea. The structures of the new compounds, characterized with 19-hydroxy groups, were identified on the basis of extensive spectral analysis as well as by comparison with literature data. This is the first report of 19-hydroxy steroids from a gorgonian and suggests a possible biosynthetic relationship between 19-nor and 19-hydroxy steroids.
authors.affiliation: State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China.
authors.forename: Wen
authors.initials: W
authors.lastname: Zhang
authors.forename: Yue-Wei
authors.initials: YW
authors.lastname: Guo
authors.forename: Ernesto
authors.initials: E
authors.lastname: Mollo
authors.forename: Angelo
authors.initials: A
authors.lastname: Fontana
authors.forename: Guido
authors.initials: G
authors.lastname: Cimino
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009792:Oceans and Seas; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D013256:Steroids