title: Massive deep venous thrombosis and venous gangrene in a 29-year-old case: metastatic epidermoid carcinoma with an unknown primary.
abstract: Cancer-associated venous thromboembolism is a severe form of paraneoplastic syndrome. It rarely leads to venous gangrene. We report a case who presented with multiple deep venous thrombosis and venous gangrene of the lower extremity. During the follow-up period, the patient developed bilateral cervical and right supraclavicular lymphadenopathies. The fine needle aspiration of the lymph nodes revealed metastatic epidermoid carcinoma of an unknown primary. Thrombotic manifestations may complicate the clinicopathological course of malignancies.
authors.affiliation: Unit of Rheumatology, Hacettepe University Medical Faculty Hospital, Ankara, Turkey.
authors.forename: Sule
authors.initials: S
authors.lastname: Apras
authors.forename: Rengin
authors.initials: R
authors.lastname: Elsurer
authors.forename: Meral
authors.initials: M
authors.lastname: Calguneri
authors.forename: Ibrahim C
authors.initials: IC
authors.lastname: Haznedaroglu
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Ozbalkan
authors.forename: Gul
authors.initials: G
authors.lastname: Karakaya
authors.forename: Lutfi
authors.initials: L
authors.lastname: Coplu
mesh_terms: D000328:Adult; D044963:Biopsy, Fine-Needle; D002277:Carcinoma / Q000150:complications / Q000473:pathology*; D005734:Gangrene / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007866:Leg / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology*; D008206:Lymphatic Diseases / Q000150:complications / Q000473:pathology*; D008297:Male; D009362:Neoplasm Metastasis / Q000473:pathology; D011859:Radiography; D020246:Venous Thrombosis / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*