[Multiple factors in erythrocytic recovery following ABO-incompatible allogeneic HSCT].
This study was aimed to investigate various factors influening erythrocyte recovery following ABO-incompatible allogeneic HSCT. 157 patients following ABO-incompatible allogeneic HSCT were selected for the investigation. Cox regression analysis were used to identify the statistically significant factors including sex, age, schemes of transplantation, HLA-matched, mismathed, conditioning regimens, preventive measures for GVHD, occurrence of grade I-II GVHD, CMV infections and types of incompatible blood group. The results showed that minor ABO-incompatible, number of mononuclear cells infused, age of patients and unrelated BMT were four important main factors influening the erythrocyte recovery. In conclusion, the erythrocyte recovery is more quick in patients with minor ABO-incompatible and more number of mononuclear cells infused, while it is slow in patents with old age and unrelated BMT.
Huang
Xiao-Jun
XJ
Institute of Hematology, People Hospital, Peking University, Beijing 100044, China.
Liu
Dai-Hong
DH
Xu
Lan-Ping
LP
Han
Wei
W
Jiang
Qian
Q
Chen
Yu-Hong
YH
Zhang
Yao-Chen
YC
Liu
Kai-Yan
KY
Bao
Li
L
Lu
Dao-Pei
DP
D000017:ABO Blood-Group System; D000293:Adolescent; D000328:Adult; D001787:Blood Group Incompatibility / Q000097:blood* / Q000150:complications; D004906:Erythrocyte Count; D004912:Erythrocytes / Q000166:cytology*; D005260:Female; D006086:Graft vs Host Disease / Q000209:etiology / Q000517:prevention & control; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects / Q000379:methods* / Q000706:statistics & numerical data; D006801:Humans; D007938:Leukemia / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D016016:Proportional Hazards Models; D012044:Regression Analysis; D012189:Retrospective Studies; D014184:Transplantation, Homologous
D000017:ABO Blood-Group System