title: [Study on the effects of two kinds of cactus polysaccharide on erythrocyte membrane protein and fluidity of the lipid in S180 mice].
abstract: OBJECTIVE
  To study the effects of two kinds of cactus polysaccharide on Band 3 protein, cross-linking protein and lipid fluidity of erythrocyte membrane in S180 mice.
  
  
  METHODS
  The membrane protein content was analysed by SDS-PAGE. Lipid fluidity was measured by Skinitzky method.
  
  
  RESULTS
  The two kinds of cactus polysaccharide increased the content of Band 3 protein and decreased the content of cross-linking protein, raised the lipid fluidity. While the effect of median dose group of medical cactus polysaccharide is very remarkable (P < 0.01), the effect of high dose group of edible cactus polysaccharide is very remarkable (P < 0.01).
  
  
  CONCLUSIONS
  By improving the erythrocyte membrane function of tumor-mice, they enhanced the immune function, which may be one of anti-tumor mechanisms.
authors.affiliation: Postdoctal Research of the Institute of Materia Medica, Harbin University of Commerce, Harbin 150076, China.
authors.forename: Yu-bin
authors.initials: YB
authors.lastname: Ji
authors.forename: Chen-feng
authors.initials: CF
authors.lastname: Ji
authors.forename: Xiang
authors.initials: X
authors.lastname: Zou
authors.forename: Shi-yong
authors.initials: SY
authors.lastname: Gao
mesh_terms: D000818:Animals; D001457:Anion Exchange Protein 1, Erythrocyte / Q000378:metabolism*; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004910:Erythrocyte Membrane / Q000378:metabolism* / Q000502:physiology; D008297:Male; D008560:Membrane Fluidity / Q000187:drug effects; D051379:Mice; D029747:Opuntia / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D011134:Polysaccharides / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D012510:Sarcoma 180 / Q000378:metabolism*
chemical_list: D001457:Anion Exchange Protein 1, Erythrocyte; D000972:Antineoplastic Agents, Phytogenic; D011134:Polysaccharides