[Cytokines in cardiovascular diseases. Role in pathogenesis, effect on prognosis, therapeutic perspectives].
During the last ten years many papers were published providing evidence of elevated serum concentrations of different cytokines in the majority of cardiovascular dieseases. Eventually it was demonstrated that they exert various effects on the heart muscle and vascular wall and thus have an impact on the patient's prognosis. Nowadays even a cytokine hypothesis of cardiovascular diseases exists. The objective of the work is to give an account of contemporary findings on the importance of cytokines in the pathogenesis of cardiovascular diseases and possibilities of therapeutic interventions.
Penicka
M
M
Kardiocentrum Fakultní nemocnice Královské Vinohrady a 3. LF UK, Praha.
Gregor
P
P
D000818:Animals; D009202:Cardiomyopathies / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000503:physiopathology* / Q000628:therapy; D016207:Cytokines / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D017202:Myocardial Ischemia / Q000503:physiopathology; D009206:Myocardium / Q000378:metabolism; D011379:Prognosis
D016207:Cytokines