Pigmented apocrine hamartoma of the vulva: a report of two cases.
Two cases of pigmented apocrine hamartoma of the vulva are reported; only one similar case involving the vulva was found in the literature. In each of the two cases, the lesion presented as a pigmented papule involving the labium minus of a young woman, and raised clinical concern for a malignant melanoma. On histological examination, the lesions were composed of tubules and cysts lined by melanin-containing apocrine cells and an outer layer of myoepithelial cells. The pigmentation appeared to be secondary to colonization of the apocrine cells by dendritic melanocytes.
Chen
Karl T K
KT
Department of Pathology Saint Agnes Medical Center, Fresno, CA 93720, USA. chenka@samc.com
D000293:Adolescent; D000328:Adult; D001050:Apocrine Glands / Q000473:pathology*; D001706:Biopsy; D005260:Female; D005500:Follow-Up Studies; D006222:Hamartoma / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008544:Melanocytes / Q000473:pathology; D010858:Pigmentation; D014844:Vulva / Q000601:surgery; D014845:Vulvar Diseases / Q000473:pathology* / Q000601:surgery