The effect of dietary and plasma fatty acids on platelet aggregation in senior generation of Japanese women.
Dietary factors that influence platelet aggregation have not been fully clarified in humans. 63 Japanese women, aged 40-70 years old, completed one-day weighted dietary records, and received physical and laboratory examinations. Platelet aggregation was measured by 1.0 and 3.0 microM ADP induction. The results were analyzed with special reference to fatty acids. The short and medium chain fatty acid intake showed negative correlation with maximum percent of platelet aggregation induced by 1.0 microM ADP. Short and medium chain fatty acids in this study were mostly derived from milk and dairy products. Importance of short and medium chain fatty acid intake on platelet aggregation requires further study for prevention of cardiovascular diseases.
Takachi
Ribeka
R
Department of Applied Bioscience, Tokyo University of Agriculture, Sakuragaoka, Setagaya, Tokyo 156-8502, Japan.
Kimira
Mitsuru
M
Uesugi
Sayo
S
Kudo
Yoko
Y
Ouchi
Kazuyuki
K
Watanabe
Shaw
S
D000273:Adipose Tissue / Q000033:anatomy & histology; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D015930:Diet Records; D004041:Dietary Fats / Q000494:pharmacology*; D005227:Fatty Acids / Q000097:blood*; D005260:Female; D006801:Humans; D007564:Japan; D008875:Middle Aged; D009929:Organ Size; D010974:Platelet Aggregation / Q000187:drug effects / Q000502:physiology*
D004041:Dietary Fats; D005227:Fatty Acids