title: [Reversible lower limb lymphedema as the first manifestation of cutaneous periarteritis nodosa].
abstract: BACKGROUND
  Cutaneous periarteritis nodosa is a localized form middle-sized arteriolitis. Its main clinical features are nodules, livedo reticularis and ulcers of the lower limbs.
  
  
  METHODS
  We reported a 45 year-old woman with distal lower limb lymphedema. Lymphedema initially spontaneously remitted but recurred nine months after, accompanied with nodules. Cutaneous periarteritis nodosa was diagnosed on histological findings and absence of extracutaneous manifestations. Lymphoscintigraphy showed functional lymphatic insufficiency. Treatment consisted of prednisone followed by colchicine and dapsone. After six months of follow-up, patient remained symptom-free.
  
  
  CONCLUSIONS
  We report the first case of lower limb lymphedema associated with cutaneous periarteritis nodosa. Parallel course and unusual corticosensivity of lymphedema and nodules raised the problem of their non coincidental association.
authors.affiliation: Unité de Lymphologie, hôpital Cognacq-Jay, site Broussais, 102, rue Didot, 75014 Paris, France. stephane.vignes@hopital-cognacq-jay.fr <stephane.vignes@hopital-cognacq-jay.fr>
authors.forename: S
authors.initials: S
authors.lastname: Vignes
authors.forename: M
authors.initials: M
authors.lastname: Stoyanova
authors.forename: E
authors.initials: E
authors.lastname: Vasseur
authors.forename: G
authors.initials: G
authors.lastname: Haicault de la Regontais
authors.forename: T
authors.initials: T
authors.lastname: Hanslik
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D003078:Colchicine / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006074:Gout Suppressants / Q000627:therapeutic use; D006801:Humans; D007866:Leg / Q000473:pathology; D008209:Lymphedema / Q000188:drug therapy / Q000209:etiology*; D008875:Middle Aged; D010488:Polyarteritis Nodosa / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D011379:Prognosis; D012008:Recurrence; D012075:Remission, Spontaneous
chemical_list: D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D006074:Gout Suppressants; D003622:Dapsone; D003078:Colchicine; D011241:Prednisone