[Effect of temperature of fluid infusion on diamine oxidase, MB isoenzyme of creatine kinase, creatine-kinase and lactate dehydrogenase in hemorrhagic shock rabbits].
OBJECTIVE
To investigate the effects of different temperatures of fluid infusion on diamine oxidase(DAO), MB isoenzyme of creatine kinase (CK-MB), creatine kinase (CK) and lactate dehydrogenase (LDH) in rabbit with hemorrhagic shock so as to provide a clue to improve the nursing care in patients with hemorrhagic shock.


METHODS
An animal model of controlled hemorrhagic shock in rabbits as previously reported was used in this randomized experiment. Twenty-three rabbits were randomized to a warm fluid infusion group (n=8), a ambient-temperature fluid infusion group (n=7), and a cold fluid infusion group (n=8). The rabbits were then resuscitated with Ringer's lactate solution three times of that of blood loss. DAO and values of myocardial enzyme were measured before shock, during shock and 1 hour, 2 hours and 4 hours after fluid infusion, respectively.


RESULTS
There was no significant difference in DAO and values of myocardial enzymes among groups, though there was a lower value in DAO and values of myocardial enzymes at 1 hour to 4 hours after warm fluid infusion.


CONCLUSIONS
Our data indicate that warm fluid infusion in rabbit model of controlled hemorrhagic shock has some beneficial effect on some biochemical values. In view of this result, temperature of fluid infusion in nursing care for patients with hemorrhagic shock should pay more attention to.
Liu
Yu-chun
YC
Nursing Department, General Hospital of PLA, Beijing 100853, China. zhhao@sina.com
Ma
Yan-lan
YL
Wang
Jian-rong
JR
Su
Rong
R
D006631:Amine Oxidase (Copper-Containing) / Q000097:blood; D000818:Animals; D003402:Creatine Kinase / Q000097:blood; D004195:Disease Models, Animal; D005440:Fluid Therapy; D007527:Isoenzymes / Q000097:blood; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D011817:Rabbits; D011897:Random Allocation; D012771:Shock, Hemorrhagic / Q000201:enzymology* / Q000628:therapy; D013696:Temperature
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D006631:Amine Oxidase (Copper-Containing); D003402:Creatine Kinase