A new triterpenoid ester from the fruits of Bruguiera parviflora.
A new lupane caffeoyl ester (1), 3-(Z)-caffeoyllupeol, together with five known triterpenoids, lupeol caffeate (2), 3-(Z)-coumaroyllupeol (3), dioslupecin A (4), lupeol (5), and lupenone (6), were isolated from the fruits of Bruguiera parviflora. Their structures were elucidated by spectroscopic methods. Compound 1 exhibited antimalarial activity with an EC50 value of 8.6 microg/ml, but compound 2 was inactive.
Chumkaew
Parinuch
P
School of Science, Walailak University, Thasala, Nakhon Si Thammarat, Thailand.
Kato
Shigeru
S
Chantrapromma
Kan
K
D000818:Animals; D005638:Fruit; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010963:Plasmodium falciparum / Q000187:drug effects / Q000502:physiology; D043982:Rhizophoraceae; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology
D010936:Plant Extracts; D014315:Triterpenes