title: An outbreak of Dipodascus capitatus infection in the ICU: three case reports and review of the literature.
abstract: A mini epidemic of Dipodascus capitatus (teleomorph of Geotrichum capitatum) involving three cases is reported. The index case was pulmonary infection and a fulminant course of fungal infection, which resulted in the patient's death with acute myelocytic leukemia. In the other cases, the patients were simultaneously hospitalized, the first in the intensive care unit. In all cases, D. capitatus was identified in different samples (sputum, deep tracheal aspiration, blood, and urine) from each of the patients. Growing evidence indicates that D. capitatus should be added to the lengthening list of opportunistic fungal pathogens that can cause infection in people of all ages and particularly in those who are immunocompromised. Further, the danger of cross-contamination and potential "outbreak" should be kept in mind during hospital management.
authors.affiliation: Department of Clinical Microbiology and Infectious Diseases, Mersin University School of Medicine, Mersin, Turkey. gersoz@mersin.edu.tr
authors.forename: Gulden
authors.initials: G
authors.lastname: Ersoz
authors.forename: Feza
authors.initials: F
authors.lastname: Otag
authors.forename: Zayre
authors.initials: Z
authors.lastname: Erturan
authors.forename: Gonul
authors.initials: G
authors.lastname: Aslan
authors.forename: Ali
authors.initials: A
authors.lastname: Kaya
authors.forename: Gürol
authors.initials: G
authors.lastname: Emekdas
authors.forename: Takashi
authors.initials: T
authors.lastname: Sugita
mesh_terms: D000328:Adult; D000368:Aged; D003428:Cross Infection / Q000382:microbiology*; D004271:DNA, Fungal / Q000302:isolation & purification; D004275:DNA, Ribosomal / Q000302:isolation & purification; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000453:epidemiology* / Q000382:microbiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology; D019105:Random Amplified Polymorphic DNA Technique; D004718:Saccharomycetales / Q000302:isolation & purification*
chemical_list: D004271:DNA, Fungal; D004275:DNA, Ribosomal