title: Tyrosinase-inhibitory long-chain esters from Amberboa ramosa.
abstract: Long-chain esters 1 and 2 have been isolated from the chloroform-soluble fraction of Amberboa ramosa and their structures assigned to be methyl 2beta(2S)-hydroxyl-7(E)-tritriacontenoate (1) and methyl 2beta(2S)-O-beta-D-galactopyranosyl-7(E)-tetratriacontenoate (2). In addition, tricontane (3) and apigenin (4) are also reported for the first time from this species. The structures were assigned on the basis of 1D and 2D NMR techniques. Compounds 1 and 2 showed strong to moderate inhibitory activity against tyrosinase.
authors.affiliation: International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, Pakistan.
authors.forename: Sher Bahadar
authors.initials: SB
authors.lastname: Khan
authors.lastname: Azhar-Ul-Haq
authors.forename: Nighat
authors.initials: N
authors.lastname: Afza
authors.forename: Abdul
authors.initials: A
authors.lastname: Malik
authors.forename: Mahmud Tariq Hasan
authors.initials: MT
authors.lastname: Khan
authors.forename: Muhammad Raza
authors.initials: MR
authors.lastname: Shah
authors.forename: Muhammad Iqbal
authors.initials: MI
authors.lastname: Choudhary
mesh_terms: D019659:Asteraceae; D004952:Esters; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010455:Peptides / Q000737:chemistry* / Q000302:isolation & purification*; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D004952:Esters; D010455:Peptides; D010936:Plant Extracts; D014442:Monophenol Monooxygenase