title: [Effects of different positive end expiratory pressure levels on resting energy expenditure measured by indirect calorimeter in patients with pressure-controlled ventilation].
abstract: OBJECTIVE
  To identify variations during measurements of resting energy expenditure (REE), oxygen consumption (VO2) and CO2 production (VCO2) by indirect calorimetry (IC) in patients with pressure-controlled ventilation and different levels of positive end expiratory pressure (PEEP).
  
  
  METHODS
  Prospective and comparative study.
  
  
  METHODS
  Intensive care unit (ICU) of a university-affiliated hospital.
  
  
  RESULTS
  REE, VO2, and VCO2 were measured by IC in nine patients with pressure-controlled ventilation and different levels of PEEP. Paired t Wilcoxon and coeficient of variation tests for all measurements were carried out. Decrease in REE, VCO2, and VO2 was observed with increments in PEEP, these changes related with a concomitant reduction in VE. Coefficient of variation during IC was above 6%, and was lower in three patients who maintained the same VE throughout the study.
  
  
  CONCLUSIONS
  Measurement of REE by IC is reliable at various levels of PEEP, and it improves if VE remains constant throughout measurement. Respiratory quotient (RQ) in this setting is not accurate.
authors.affiliation: Unidad de Cuidados Intensivos y Medicina Crítica, Hospital de Especialidades Dr. Bernardo Sepúlveda del Centro Médico Nacional Siglo XXI, IMSS, México DF, México. jorgec@prodigy.net.mx
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Castañón-González
authors.forename: Julián
authors.initials: J
authors.lastname: Satué-Rodríguez
authors.forename: José Sergio
authors.initials: JS
authors.lastname: Camacho-Juárez
authors.forename: Francisco
authors.initials: F
authors.lastname: Carrillo-Rosales
authors.forename: Marco Antonio
authors.initials: MA
authors.lastname: León-Gutiérrez
authors.forename: Rogelio
authors.initials: R
authors.lastname: Miranda-Ruiz
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002153:Calorimetry, Indirect; D004734:Energy Metabolism; D006801:Humans; D008875:Middle Aged; D011175:Positive-Pressure Respiration / Q000379:methods*; D011446:Prospective Studies; D012146:Rest / Q000502:physiology*