[The animal model of anxious depression: persistence of behavior pathology].
It has been shown that chronic psychoemotional stress caused by repeated experience of defeats in agonistic interactions during 30 days led to development of the anxiety depression--like state accompanied by pronounced anxiety, behavioral deficit, decreased communication, and increased depressiveness as estimated by various behavioral tests in male mice. This psychopathological state still existed after 1-2 weeks living with females in comfortable conditions (without confrontations with other males), that testified to persistence of behavior pathology.
Avgustinovich
D F
DF
Kovalenko
I L
IL
Kudriavtseva
N N
NN
D000374:Aggression; D000818:Animals; D001522:Behavior, Animal; D003220:Conflict, Psychological; D003863:Depression / Q000473:pathology / Q000503:physiopathology*; D004195:Disease Models, Animal; D005260:Female; D008297:Male; D051379:Mice