title: Reaction of mouse subcutaneous tissue to Carisolv--a morphologic study.
abstract: This study was designed to investigate in vivo subcutaneous tissue reactions after Carisolv contact in a mouse model. Eighteen mice were implanted with two polyethylene tubes: the implant on the right side included a sponge soaked in Carisolv; the implant on the left side served as a control. Similar tissue response was displayed in both test and control groups, suggesting that Carisolv does not result in adverse effects as compared with a control. The tendency of connective tissue encapsulating the implants in both groups may result from the presence of materials that can be well-tolerated by the organism.
authors.affiliation: Health Science Center, University of Brasilia, Brazil.
authors.forename: Patrícia Medeiros
authors.initials: PM
authors.lastname: Berto
authors.forename: Anne Caroline
authors.initials: AC
authors.lastname: Rickli
authors.forename: Camila Silva de Andrade
authors.initials: CS
authors.lastname: Melo
authors.forename: Luciano Paulino
authors.initials: LP
authors.lastname: da Silva
authors.forename: Ana Cristina Barreto
authors.initials: AC
authors.lastname: Bezerra
authors.forename: Orlando Ayrton
authors.initials: OA
authors.lastname: de Toledo
mesh_terms: D000818:Animals; D003737:Dental Cavity Preparation / Q000009:adverse effects; D003764:Dental Materials / Q000633:toxicity*; D005260:Female; D018698:Glutamic Acid / Q000633:toxicity*; D007930:Leucine / Q000633:toxicity*; D008239:Lysine / Q000633:toxicity*; D051379:Mice; D008807:Mice, Inbred BALB C; D040521:Subcutaneous Tissue / Q000187:drug effects*
chemical_list: C119934:Carisolv; D003764:Dental Materials; D018698:Glutamic Acid; D007930:Leucine; D008239:Lysine