title: Osteochondral defects of the talus treated by mesenchymal stem cell implantation--early results.
abstract: The purpose of this study was to present early results of talus cartilage defects treatment with autologous mesenchymal stem cells CD34+ implantation technique. Nine (9) patients were treated, due to IV degree chondromalation (by ICRS). The applied standard procedure included: clinical examination, AP and lateral x-ray, MRI, preoperative, as well as during control examination. The surgical procedure consisted of the defect's debridement, harvesting and fixation of the periosteal flap and CD34+ implantation. Clinical results were assessed after 6 months to 3 years by clinical examination, Magee score and MRI. Good and very good clinical results were obtained and confirmed by MRI in 8 cases. In one case, cartilage hypertrophy was noted. There were no delamination and infection signs.
authors.affiliation: Department of Orthopaedics and Traumatology, Medical University of Bialystok, Bialystok, Poland. ortopamb@o2.pl
authors.forename: P
authors.initials: P
authors.lastname: Jancewicz
authors.forename: W
authors.initials: W
authors.lastname: Dzienis
authors.forename: M
authors.initials: M
authors.lastname: Pietruczuk
authors.forename: J
authors.initials: J
authors.lastname: Skowroński
authors.forename: M
authors.initials: M
authors.lastname: Bielecki
mesh_terms: D002358:Cartilage, Articular; D003646:Debridement; D006801:Humans; D008648:Mesoderm / Q000637:transplantation; D016343:Monitoring, Intraoperative; D010008:Osteochondritis Dissecans / Q000601:surgery / Q000628:therapy*; D033581:Stem Cell Transplantation; D013628:Talus / Q000293:injuries*