title: Cytotoxic iridoid aldehydes from Taiwanese Viburnum luzonicum.
abstract: Four new iridoid aldehydes bearing (E)- or (Z)-p-coumaroyl group, luzonial A (1), luzonial B (2), luzonidial A (3), and luzonidial B (4), were isolated from a methanol extract of the dried leaves of Viburnum luzonicum collected in Kaoshiung, Taiwan and their structures were elucidated by analysis of spectroscopic data. Compounds 1-3 exhibited moderate inhibitory activity against HeLa S3 cancer cells.
authors.affiliation: Institute of Pharmacognosy, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan. fukuyama@ph.bunri-u.ac.jp
authors.forename: Yoshiyasu
authors.initials: Y
authors.lastname: Fukuyama
authors.forename: Yuka
authors.initials: Y
authors.lastname: Minoshima
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Kishimoto
authors.forename: Ih-Sheng
authors.initials: IS
authors.lastname: Chen
authors.forename: Hironobu
authors.initials: H
authors.lastname: Takahashi
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Esumi
mesh_terms: D000447:Aldehydes / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity*; D049109:Cell Proliferation / Q000187:drug effects; D006367:HeLa Cells; D006801:Humans; D039823:Iridoids / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity*; D018515:Plant Leaves; D013624:Taiwan; D027925:Viburnum
chemical_list: D000447:Aldehydes; D039823:Iridoids; D010936:Plant Extracts