title: Thrombin-directed inhibitors: pharmacology and clinical use.
authors.affiliation: University of Connecticut, Hartford Hospital, Hartford, Conn 06102-5037, USA. cmwhite@harthosp.org
authors.forename: C Michael
authors.initials: CM
authors.lastname: White
mesh_terms: D000925:Anticoagulants / Q000378:metabolism / Q000494:pharmacology*; D001120:Arginine / Q000031:analogs & derivatives; D001384:Azetidines / Q000378:metabolism / Q000494:pharmacology; D001596:Benzylamines; D001777:Blood Coagulation; D000077425:Fondaparinux; D006493:Heparin / Q000494:pharmacology; D006629:Hirudins / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D010446:Peptide Fragments / Q000378:metabolism / Q000494:pharmacology; D010875:Pipecolic Acids / Q000378:metabolism / Q000494:pharmacology; D011134:Polysaccharides / Q000378:metabolism / Q000494:pharmacology; D011994:Recombinant Proteins / Q000378:metabolism / Q000494:pharmacology; D013449:Sulfonamides; D013917:Thrombin / Q000037:antagonists & inhibitors*; D013927:Thrombosis; D014859:Warfarin / Q000494:pharmacology
chemical_list: D000925:Anticoagulants; D001384:Azetidines; D001596:Benzylamines; D006629:Hirudins; D010446:Peptide Fragments; D010875:Pipecolic Acids; D011134:Polysaccharides; D011994:Recombinant Proteins; D013449:Sulfonamides; C426686:ximelagatran; D014859:Warfarin; D006493:Heparin; D001120:Arginine; D013917:Thrombin; C031942:argatroban; D000077425:Fondaparinux; C074619:bivalirudin; C060225:desirudin; C083544:lepirudin