AIDS, multicentric Castleman's disease, and plasmablastic leukemia: report of a long-term survival.
Plasmablastic leukemia (PL) as a complication of human herpes virus 8 (HHV8)-associated Castleman's disease is marked by a rapid and fatal outcome. In patients with AIDS, survival of 7 to 14 days after diagnosis has been reported. Prompt splenectomy and chemotherapy might lead to a significant survival benefit. Here we report a case of long-term survival in a patient with AIDS and multicentric Castleman's disease (MCD) complicated by PL.
Horster
S
S
Medical Policlinic, Pettenkoferstr. 8a, D-80336 Munich, Germany. sophiahorster@gmx.de
Jung
C
C
Zietz
C
C
Cohen
C D
CD
Siebeck
M
M
Goebel
F D
FD
D017088:AIDS-Related Opportunistic Infections / Q000821:virology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005871:Castleman Disease / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D006566:Herpesviridae Infections / Q000209:etiology*; D019288:Herpesvirus 8, Human; D006801:Humans; D007952:Leukemia, Plasma Cell / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D008297:Male; D013156:Splenectomy