title: Effect of inoculum size on detection of Candida growth by the BACTEC 9240 automated blood culture system using aerobic and anaerobic media.
abstract: Simulated candidemia was produced with 20 Candida isolates at three inoculum sizes (100, 10, and 1 CFU/ml of blood). Growth detection was better with larger inocula. The time to growth detection was shorter with larger inocula. Inoculum size does effect Candida growth detection and time to detection in BACTEC 9240 automated systems.
authors.affiliation: Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA.
authors.forename: Benjamin J
authors.initials: BJ
authors.lastname: George
authors.forename: Lynn L
authors.initials: LL
authors.lastname: Horvath
authors.forename: Duane R
authors.initials: DR
authors.lastname: Hospenthal
mesh_terms: D000332:Aerobiosis; D000693:Anaerobiosis; D001769:Blood / Q000382:microbiology*; D002175:Candida / Q000145:classification / Q000254:growth & development* / Q000302:isolation & purification; D002176:Candida albicans / Q000254:growth & development / Q000302:isolation & purification; D002177:Candidiasis / Q000382:microbiology; D003470:Culture Media; D016469:Fungemia / Q000382:microbiology*; D006801:Humans; D008828:Microbiological Techniques; D011933:Reagent Kits, Diagnostic
chemical_list: D003470:Culture Media; D011933:Reagent Kits, Diagnostic