title: Endoscopic resection of Peutz-Jeghers polyps throughout the small intestine at double-balloon enteroscopy without laparotomy.
abstract: BACKGROUND
  Small-bowel enteroscopy with the double-balloon method was developed to improve access to the small intestine. This study evaluated the usefulness of this method for the resection of small-intestinal Peutz-Jeghers polyps.
  
  
  METHODS
  Two patients with Peutz-Jeghers syndrome underwent nonsurgical double-balloon enteroscopic resection of polyps throughout the small intestine.
  
  
  METHODS
  Multiple polyps in the jejunum were successfully resected via the oral route, as were the polyps in the ileum via the anal route. All 18 polyps (10-60 mm in size) were resected without subsequent bleeding or perforation. Histopathologically, 3 large polyps (>30 mm diameter) were hamartomas with adenomatous components.
  
  
  CONCLUSIONS
  Double-balloon enteroscopy was safe and useful for the diagnosis and the treatment of Peutz-Jeghers polyps throughout the small intestine. Double-balloon enteroscopic polypectomy might preclude complications of Peutz-Jeghers syndrome, including intussusception, bleeding, and tumorogenesis, thereby obviating the need for multiple laparotomies.
authors.affiliation: Division of Gastroenterology, Department of Therapeutic Medicine, Nagoya, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Ohmiya
authors.forename: Ayumu
authors.initials: A
authors.lastname: Taguchi
authors.forename: Kennosuke
authors.initials: K
authors.lastname: Shirai
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Mabuchi
authors.forename: Daigo
authors.initials: D
authors.lastname: Arakawa
authors.forename: Hironobu
authors.initials: H
authors.lastname: Kanazawa
authors.forename: Masayasu
authors.initials: M
authors.lastname: Ozeki
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yamada
authors.forename: Masanao
authors.initials: M
authors.lastname: Nakamura
authors.forename: Akihiro
authors.initials: A
authors.lastname: Itoh
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Hirooka
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Niwa
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Nagasaka
authors.forename: Masafumi
authors.initials: M
authors.lastname: Ito
authors.forename: Shinji
authors.initials: S
authors.lastname: Ohashi
authors.forename: Shozo
authors.initials: S
authors.lastname: Okamura
authors.forename: Hidemi
authors.initials: H
authors.lastname: Goto
mesh_terms: D000328:Adult; D002404:Catheterization; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D005260:Female; D006801:Humans; D007417:Intestinal Polyps / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D007421:Intestine, Small; D008297:Male; D010580:Peutz-Jeghers Syndrome / Q000150:complications*