title: Timely reconstitution of immune competence affects clinical outcome following autologous stem cell transplantation.
abstract: The anti-tumor activity of the immune system in the setting of hematopoietic stem cell transplantation has largely been described in the context of the "graft-versus-tumor" effect of allogeneic stem cell transplantation. This article reviews clinical evidence suggesting the existence of an autologous graft-versus-tumor effect in the setting of host immune system recovery following autologous stem cell transplantation resulting in prolongation of survival of cancer patients.
authors.affiliation: Division of Hematology, Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
authors.forename: L F
authors.initials: LF
authors.lastname: Porrata
authors.forename: S N
authors.initials: SN
authors.lastname: Markovic
mesh_terms: D020350:Graft vs Tumor Effect / Q000276:immunology*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007121:Immunocompetence; D007694:Killer Cells, Natural / Q000276:immunology; D018655:Lymphocyte Count; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous