title: Antioxidant activity of Cassia fistula (Linn.) flowers in alloxan induced diabetic rats.
abstract: Aqueous extract of Cassia fistula (Linn.) flowers (ACF) was screened for its antioxidant effect in alloxan induced diabetic rats. An appreciable decrease in peroxidation products viz thiobarbituric acid reactive substances, conjugated dienes, hydroperoxides was observed in heart tissues of ACF treated diabetic rats. The decreased activities of key antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase and glutathione in diabetic rats were brought back to near normal range upon ACF treatment. These results suggest that ACF has got promising antioxidative activity in alloxan diabetic rats.
authors.affiliation: Department of Biochemistry and Molecular Biology, Guindy Campus, University of Madras, Chennai 600025, India. gmanonmani@yahoo.com
authors.forename: G
authors.initials: G
authors.lastname: Manonmani
authors.forename: V
authors.initials: V
authors.lastname: Bhavapriya
authors.forename: S
authors.initials: S
authors.lastname: Kalpana
authors.forename: S
authors.initials: S
authors.lastname: Govindasamy
authors.forename: T
authors.initials: T
authors.lastname: Apparanantham
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000302:isolation & purification / Q000627:therapeutic use*; D002366:Cassia; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy* / Q000378:metabolism; D005260:Female; D035264:Flowers; D010936:Plant Extracts / Q000302:isolation & purification / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000975:Antioxidants; D010936:Plant Extracts