title: Traumatic central cord syndrome: analysis of factors affecting the outcome.
abstract: BACKGROUND
  The indications and timing of treatment, as well as the best treatment method for traumatic central cord syndrome (CCS), remain controversial. The aims of this study are to determine the prognostic factors of traumatic CCS and to determine appropriate surgical indications.
  
  
  METHODS
  We reviewed the clinical and radiological data of 47 patients with this syndrome. The data collected included age, neurological status as measured on a scale defined by the Japanese Orthopaedic Association (JOA), anteroposterior (AP) diameter of the spinal canal on computed tomography, signal intensity change of the spinal cord on T2-weighted magnetic resonance imaging (MRI), associated spinal diseases, and the type of treatment received. The correspondence between the clinical and radiological findings and the neurological outcome was investigated.
  
  
  RESULTS
  The patient's age, JOA score on admission, signal intensity change of the spinal cord on MRI, and associated spinal diseases were not significant in predicting the patient's recovery. On the other hand, the AP diameter of the spinal canal (P = .0402) and the interval between injury and surgery (P < .0001) were factors predictive of excellent recovery. In the surgical treatment group, timely surgery was found to improve the outcome, while conservative treatment did not improve the outcome of patients with a low JOA score, a relatively small AP diameter of the spinal canal, or a positive signal intensity change of the spinal cord on T2-weighted MRI.
  
  
  CONCLUSIONS
  The AP canal diameter of the spinal canal and the interval between injury and surgery may be reliable predictors of excellent recovery in patients with CCS. We recommend timely surgery, preferably within 2 weeks of injury, to achieve a better functional outcome in selected patients.
authors.affiliation: Department of Neurosurgery, Ibaraki Seinan Medical Center, Sashima 305-8575, Japan.
authors.forename: Tomosato
authors.initials: T
authors.lastname: Yamazaki
authors.forename: Kiyoyuki
authors.initials: K
authors.lastname: Yanaka
authors.forename: Keishi
authors.initials: K
authors.lastname: Fujita
authors.forename: Takao
authors.initials: T
authors.lastname: Kamezaki
authors.forename: Kazuya
authors.initials: K
authors.lastname: Uemura
authors.forename: Tadao
authors.initials: T
authors.lastname: Nose
mesh_terms: D020210:Central Cord Syndrome / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D019299:Decompression, Surgical; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D017063:Outcome Assessment, Health Care; D011379:Prognosis; D013115:Spinal Canal / Q000473:pathology; D013116:Spinal Cord / Q000473:pathology / Q000601:surgery; D013117:Spinal Cord Compression / Q000473:pathology / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome