title: New developments in diagnosis and treatment of Parkinson's disease--from basic science to clinical applications.
abstract: In this review we summarize new developments in early diagnosis, establishing surrogate markers, genetics, neuroprotection and cell replacement in Parkinson's disease. Furthermore, we discuss the major problems in the translation of results from preclinical research into successful clinical trials.
authors.affiliation: Technical University of Dresden, Department of Neurology, Fetscherstrasse 74, 01307 Dresden, Germany. alexander.storch@neuro.med.tu-dresden.de
authors.forename: Alexander
authors.initials: A
authors.lastname: Storch
authors.forename: Anne
authors.initials: A
authors.lastname: Hofer
authors.forename: Rejko
authors.initials: R
authors.lastname: Krüger
authors.forename: Jörg B
authors.initials: JB
authors.lastname: Schulz
authors.forename: Jürgen
authors.initials: J
authors.lastname: Winkler
authors.forename: Manfred
authors.initials: M
authors.lastname: Gerlach
mesh_terms: D015415:Biomarkers / Q000032:analysis; D003952:Diagnostic Imaging / Q000379:methods / Q000639:trends; D006801:Humans; D009414:Nerve Growth Factors / Q000494:pharmacology / Q000627:therapeutic use; D018696:Neuroprotective Agents / Q000494:pharmacology / Q000627:therapeutic use; D010300:Parkinson Disease / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy*; D033581:Stem Cell Transplantation / Q000379:methods / Q000639:trends; D017211:Treatment Failure
chemical_list: D015415:Biomarkers; D009414:Nerve Growth Factors; D018696:Neuroprotective Agents