Diagnostic value of the Rotterdam-CAMCOG in post-stroke dementia.
OBJECTIVE
Specific screening tests to detect post-stroke dementia are lacking. We recently reported that an adaptation of the Cambridge Cognitive Examination (CAMCOG), the Rotterdam-CAMCOG, had excellent sensitivity and specificity for detecting post-stroke dementia. In this study, we externally validated the diagnostic accuracy of the R-CAMCOG in a new, representative cohort of stroke patients.


METHODS
The R-CAMCOG and an extensive neuropsychological examination were administered, independently of each other, in 121 patients aged 55 and over with a stroke in the preceding three to nine months. The gold standard diagnosis of dementia was based on the results of the extensive neuropsychological examination, clinical presentation, and information from a close relative, as well as DSM-IV criteria.


RESULTS
Of the 121 patients, 35 had dementia (29%). The diagnostic accuracy at the pre-specified cut-off point of 33/34 was established through receiver operating characteristic (ROC) analyses (sensitivity 66%, specificity 94%). At a cut-off point of 36/37 sensitivity would be 83% and specificity 78%.


CONCLUSIONS
The R-CAMCOG is a useful screening tool for post-stroke dementia in a clinical setting.
de Koning
I
I
Department of Neurology, Erasmus MC, PO Box 2040, 3000 CA Rotterdam, the Netherlands. i.dekoning@erasmusmc.nl
van Kooten
F
F
Koudstaal
P J
PJ
Dippel
D W J
DW
D000368:Aged; D000369:Aged, 80 and over; D003704:Dementia / Q000175:diagnosis* / Q000209:etiology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008609:Mental Status Schedule; D008875:Middle Aged; D009483:Neuropsychological Tests; D012680:Sensitivity and Specificity; D020521:Stroke / Q000150:complications* / Q000523:psychology*