Investigation of the morphology of cell clones, derived from the mammalian EBTr cell line and their susceptibility to vaccine avian poxvirus strains FK and Dessau.
The ability for replication of vaccine avian pox viral strains FK and Dessau in cell clones, derived from the EBTr cell line, derived from embryonic bovine trachea, was studied. The derived seven cell clones showed different morphological characteristics and diverse sensitivity to both vaccine avian pox viral strains. Hence, the EBTr-derived cell clones could be used for cultivation, as well as for differentiation of vaccine avian pox viral strains. In addition, studies have been undertaken to elucidate the possible use of cultivated strains in these heterologous cell culture system's vaccine avian pox viral strains for biotechnology, as well as for solving problems, related to infection of people with avian viruses.
Sainova
Iskra Ventseslavova
IV
Bulgarian Academy of Sciences, Central Laboratory of Optical Storage and Processing of Information, Acad. Georgi Bonchev Street, Block 101, P.O. Box 95, 1113 Sofia, Bulgaria. isainova@optics.bas.bg
Kril
Anton Ivanov
AI
Simeonov
Konstantin Borisov
KB
Popova
Theodora Petrova
TP
Ivanov
Ivan Georgiev
IG
D000818:Animals; D018150:Avipoxvirus / Q000502:physiology*; D002417:Cattle; D002460:Cell Line; D002999:Clone Cells; D014132:Trachea / Q000166:cytology* / Q000821:virology*; D014765:Viral Vaccines; D014779:Virus Replication
D014765:Viral Vaccines