title: Postoperative alopecia in five patients after treatment of aneurysm rupture with a Guglielmi detachable coil: pressure alopecia, radiation induced, or both?
abstract: Postoperative pressure alopecia is an uncommon complication of long anesthetic surgical procedures, typically affecting the occiput and resulting from pressure-induced tissue hypoxia. Generally, it develops after procedures of long duration, of more than four hours. Most alopecia is transient, but a few cases are permanent. Guglielmi detachable coil (GDC) coiling is a procedure guided by fluoroscopy that fills an intracranial aneurysm. Our cases were characterized by an unusual distribution of alopecia, short duration of procedure, and radiation exposure. The alopecic lesions of our patients were located on the temporal scalp as well as the occipital scalp. The total time of anesthesia was relatively short, two to three hours. During the procedure, these patients were exposed to ionizing radiation (over 2Gy). These cases are different from previous reports in that the duration of the procedure was short, the temporal scalp was affected in addition to the occipital scalp, and the pathology occurred after GDC coiling.
authors.affiliation: Department of Dermatology and Institute of Hair and Cosmetic Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Won-Soo
authors.initials: WS
authors.lastname: Lee
authors.forename: Se-Won
authors.initials: SW
authors.lastname: Lee
authors.forename: Sanghoon
authors.initials: S
authors.lastname: Lee
authors.forename: Jin Wook
authors.initials: JW
authors.lastname: Lee
mesh_terms: D000328:Adult; D000505:Alopecia / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D000768:Anesthesia, General / Q000009:adverse effects / Q000379:methods; D017542:Aneurysm, Ruptured / Q000175:diagnosis / Q000628:therapy*; D001707:Biopsy, Needle; D004621:Embolization, Therapeutic / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D002532:Intracranial Aneurysm / Q000175:diagnosis / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis*; D011839:Radiation, Ionizing; D018570:Risk Assessment; D012494:Sampling Studies