title: A binaphthyl-containing Eu(III) complex and its interaction with human serum albumin: a luminescence study.
abstract: On binding to human serum albumin (HSA), the Eu(III) luminescent emission enhancement of a complex containing a binaphthyl chromophore enables the determination of binding constants, showing no chiral discrimination for the (R)- (K= 8200 +/- 810 M(-1)) and (S)-enantiomers (K= 7710 +/- 460 M(-1)).
authors.affiliation: Department of Chemistry, University of Leicester, Leicester LE1 7RH, UK.
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Hamblin
authors.forename: Neil
authors.initials: N
authors.lastname: Abboyi
authors.forename: Mark P
authors.initials: MP
authors.lastname: Lowe
mesh_terms: D005063:Europium / Q000737:chemistry*; D006801:Humans; D008024:Ligands; D049408:Luminescent Agents / Q000138:chemical synthesis / Q000737:chemistry*; D008163:Luminescent Measurements; D046911:Macromolecular Substances / Q000138:chemical synthesis / Q000737:chemistry; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D011485:Protein Binding; D012709:Serum Albumin / Q000737:chemistry*
chemical_list: C510370:2,2'-bis(bromomethyl)-1,1'-binaphthyl; D008024:Ligands; D049408:Luminescent Agents; D046911:Macromolecular Substances; D009281:Naphthalenes; D009942:Organometallic Compounds; D012709:Serum Albumin; C031721:naphthalene; D005063:Europium