title: Pyrenyldiazomethane, a versatile reagent for nucleotide phosphate alkylation.
abstract: Pyrenyldiazomethane was shown to react quantitatively and selectively at phosphate with 2'-, 3'-, and 5'-nucleotide phosphates incorporating the different nucleic bases.
authors.affiliation: LEDSS, UMR5616 CNRS-BP53, Université Joseph Fourier, 38041 Grenoble, France. kotera@bioorga.u-strasbg.fr
authors.forename: Mitsuharu
authors.initials: M
authors.lastname: Kotera
authors.forename: Marie-Louise
authors.initials: ML
authors.lastname: Dheu
authors.forename: Anne
authors.initials: A
authors.lastname: Milet
authors.forename: Jean
authors.initials: J
authors.lastname: Lhomme
authors.forename: Ali
authors.initials: A
authors.lastname: Laayoun
mesh_terms: D000478:Alkylation; D001391:Azo Compounds / Q000737:chemistry; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D015394:Molecular Structure; D009711:Nucleotides / Q000737:chemistry*; D011721:Pyrenes / Q000737:chemistry; D012997:Solvents; D013329:Structure-Activity Relationship; D013696:Temperature
chemical_list: D001391:Azo Compounds; D007202:Indicators and Reagents; D009711:Nucleotides; D011721:Pyrenes; D012997:Solvents; C500878:pyrenyldiazomethane