Conduit for privileged communications in the lymph node.
A study by Sixt et al. in this issue of Immunity identifies conduit-associated dendritic cells whose privileged access to antigen arriving by the conduit enables uptake and processing of antigen within 90 min of antigen inoculation, long before the arrival of dendritic cells from skin.
Anderson
Arthur O
AO
Department of Clinical Pathology, US Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.
Shaw
Stephen
S
D000818:Animals; D017951:Antigen Presentation; D002450:Cell Communication; D003713:Dendritic Cells / Q000276:immunology*; D008198:Lymph Nodes / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*