title: Effect of corticosteroids on short-term and long-term memory.
abstract: The effect of acute high-dose glucocorticoid therapy on memory function in patients with acute optic neuritis (n = 9) and multiple sclerosis (n = 21) was studied. All patients had reversible impairment of long-term memory functions, whereas measures of short-term memory, attentional functions, and alertness remained unaffected.
authors.affiliation: Department of Neurology, University of Heidelberg, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Brunner
authors.forename: D
authors.initials: D
authors.lastname: Schaefer
authors.forename: K
authors.initials: K
authors.lastname: Hess
authors.forename: P
authors.initials: P
authors.lastname: Parzer
authors.forename: F
authors.initials: F
authors.lastname: Resch
authors.forename: S
authors.initials: S
authors.lastname: Schwab
mesh_terms: D000293:Adolescent; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D001288:Attention / Q000187:drug effects; D005260:Female; D006624:Hippocampus / Q000187:drug effects / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008568:Memory / Q000187:drug effects*; D008569:Memory Disorders / Q000139:chemically induced* / Q000503:physiopathology; D008570:Memory, Short-Term / Q000187:drug effects; D011939:Mental Recall / Q000187:drug effects; D008775:Methylprednisolone / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000188:drug therapy* / Q000523:psychology; D009483:Neuropsychological Tests; D009902:Optic Neuritis / Q000188:drug therapy* / Q000523:psychology; D013312:Stress, Physiological / Q000523:psychology; D014706:Verbal Learning / Q000187:drug effects
chemical_list: D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone