[Differential clinical diagnostic parameters of acute hepatitis B and flare of chronic HBV infection].
OBJECTIVE
To evaluate useful clinical diagnostic parameters for differentiating acute hepatitis B and flare of chronic HBV infection.


METHODS
Using PCR method to detect viral level in the patient's serum, HBV marker was detected by ELISA kit. Liver function was also detected.


RESULTS
The patient can be diagnosed as acute hepatitis B if a patient has one of the following parameters: (1)HBV-DNA negative on admission. (2) When the patient's ALT was lower than 400 IU/L, HBV-DNA was negative or HBsAg became negative or HBeAg/HBeAb seroconverted.


CONCLUSIONS
The viral DNA level, HBV marker and ALT can help differentiate acute hepatitis B and flare of chronic HBV infection.
Zhao
Hong
H
Department of Infectious Diseases, The First Teaching Hospital of Beijing University, Beijing 100034, China.
Tian
Geng-shan
GS
D000208:Acute Disease; D000328:Adult; D000410:Alanine Transaminase / Q000097:blood*; D004279:DNA, Viral / Q000097:blood*; D003937:Diagnosis, Differential; D006509:Hepatitis B / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D006510:Hepatitis B Antibodies / Q000097:blood; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006513:Hepatitis B e Antigens / Q000097:blood; D019694:Hepatitis B, Chronic / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D008111:Liver Function Tests; D008875:Middle Aged
D004279:DNA, Viral; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens; D000410:Alanine Transaminase