Colorectal carcinoma in children, adolescents, and young adults.
The authors conducted a retrospective evaluation of patients younger than 30 years with colorectal carcinoma in Argentina. Patients were divided into group 1 (patients treated at pediatric institutions from 0 to 20 years of age, n = 14) and group 2 (patients from 21 to 30, n = 7, treated at adult centers). Group 1 had significantly more advanced disease and a poorer prognosis. Six patients (2/14 in group 1 and 4/7 in group 2) survive disease-free. Thirteen patients died of progressive disease, 1 died of a non-tumor-related cause, and 1 is still on treatment. Patients younger than 20 years have a poorer prognosis, probably because of advanced disease on presentation.
Chantada
Guillermo L
GL
Hospital J. P. Garrahan, Buenos Aires, Argentina.
Perelli
Viviana B
VB
Lombardi
Mercedes García
MG
Amaral
Diego
D
Cascallar
Diana
D
Scopinaro
Marcelo
M
Deza
Ernesto Gil
EG
Gercovich
Felipe Gustavo
FG
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D015179:Colorectal Neoplasms / Q000401:mortality* / Q000503:physiopathology* / Q000628:therapy*; D013505:Digestive System Surgical Procedures; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome