title: Cerebellar hypoperfusion in infantile neuroaxonal dystrophy.
abstract: An identical abnormal pattern was detected by means of (99m)Tc-hexamethyl-propyleneamine-oxime single-photon emission computed tomography in two siblings with infantile neuroaxonal dystrophy. The markedly decreased cerebellar perfusion, along with the early motor symptoms, characteristic magnetic resonance imaging and pathologic findings, points to a preferential cerebellar involvement in this disease. A relative increase in the perfusion to the basal ganglia correlated with the magnetic resonance imaging abnormalities, highly resembling that of Hallervorden-Spatz disease in one of the males, at this site.
authors.affiliation: Pediatrics Department, King Abdulaziz Medical City, King Fahad National Guard Hospital, PO Box 22490, Riyadh 11426, Kingdom of Saudi Arabia.
authors.forename: Jeno
authors.initials: J
authors.lastname: Kóbor
authors.forename: Ahmad
authors.initials: A
authors.lastname: Javaid
authors.forename: Matthew F
authors.initials: MF
authors.lastname: Omojola
mesh_terms: D002531:Cerebellum / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008297:Male; D019150:Neuroaxonal Dystrophies / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D011877:Radionuclide Imaging