title: Non-standard structures of the Ni-Fe cofactor in the regulatory and the NAD-reducing hydrogenases from Ralstonia eutropha.
abstract: Spectroscopy on two oxygen-insensitive Ni-Fe hydrogenases from Ralstonia eutropha (NAD-reducing, soluble hydrogenase; hydrogen sensor, regulatory hydrogenase) reveals non-standard catalytic behaviour and unique structures of their Ni-Fe cofactors. Possible mechanistic implications are briefly discussed.
authors.affiliation: Freie Universität Berlin, FB Physik, Arnimallee 14, D-14195 Berlin, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Löscher
authors.forename: T
authors.initials: T
authors.lastname: Burgdorf
authors.forename: T
authors.initials: T
authors.lastname: Buhrke
authors.forename: B
authors.initials: B
authors.lastname: Friedrich
authors.forename: H
authors.initials: H
authors.lastname: Dau
authors.forename: M
authors.initials: M
authors.lastname: Haumann
mesh_terms: D020118:Cupriavidus necator / Q000201:enzymology*; D006864:Hydrogenase / Q000737:chemistry* / Q000378:metabolism; D010088:Oxidoreductases / Q000737:chemistry* / Q000378:metabolism
chemical_list: D010088:Oxidoreductases; C043296:nickel-iron hydrogenase; C021376:hydrogen dehydrogenase; D006864:Hydrogenase