Calcium supplements to prevent colorectal adenomas.
Calcium supplements have been shown to decrease the risk of colorectal adenomas. In this issue of the Journal, Shaukat et al. report the results of a systematic review and meta-analysis of randomized controlled trials of calcium supplementation. The authors statistically combined the data from the three trials that met strict eligibility criteria. The overall relative risk was 0.80 (95% CI: 0.68-0.93) and the number needed to treat was 14. The results of this meta-analysis support a preventive role for calcium supplements.
Sandler
Robert S
RS
D000236:Adenoma / Q000517:prevention & control*; D002118:Calcium / Q000008:administration & dosage*; D018890:Chemoprevention; D015179:Colorectal Neoplasms / Q000517:prevention & control*; D019587:Dietary Supplements; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control
D002118:Calcium