title: Nutritional supplements and complementary/alternative medicine in Tourette syndrome.
abstract: OBJECTIVE
  Tourette syndrome (TS) is a neuropsychiatric disorder associated with motor and vocal tics. Some people with TS have reported using alternative or complementary medicine (CAM), including nutritional supplements to control their tics. In a recent national survey, approximately 40% of people reported having used CAM in the prior year. We attempted to explore the use of supplements and other CAM among TS patients.
  
  
  METHODS
  We developed a survey instrument based on anecdotal accounts of CAM use and distributed it to the mailing list of the New York Chapter of the Tourette Syndrome Association (n=500) and the subscription list of Latitudes, a newsletter exploring CAM treatments for neurological conditions (n=750). Responses were entered in a database and analyzed using SPSS version 10.
  
  
  RESULTS
  Of 115 respondents, 87.8% reported using 1 or more of 29 nutritional supplements to control symptoms. Many also reported using other CAM. Most supplement users reported an improvement in tics.
  
  
  CONCLUSIONS
  Although these results are not generalizable, they provide no evidence that use of supplements and other CAM is rarer among TS patients than in the general population. Given that most of our respondents were also using conventional medication, further study of the use of supplements and other CAM therapies by people with TS, the safety and efficacy of such therapies in this population, and possible interactions of such therapies with conventional treatment seems warranted.
authors.affiliation: BJM Consulting, New York, New York.
authors.forename: Barbara J
authors.initials: BJ
authors.lastname: Mantel
authors.forename: Andrea
authors.initials: A
authors.lastname: Meyers
authors.forename: Quan Y
authors.initials: QY
authors.lastname: Tran
authors.forename: Sheila
authors.initials: S
authors.lastname: Rogers
authors.forename: Judith S
authors.initials: JS
authors.lastname: Jacobson
mesh_terms: D000293:Adolescent; D000328:Adult; D002491:Central Nervous System Agents / Q000008:administration & dosage; D002648:Child; D003131:Combined Modality Therapy; D000529:Complementary Therapies / Q000706:statistics & numerical data*; D019587:Dietary Supplements / Q000706:statistics & numerical data*; D005260:Female; D019538:Health Care Surveys; D006801:Humans; D008297:Male; D005879:Tourette Syndrome / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D002491:Central Nervous System Agents