title: Changes in the parameters of left ventricular diastolic function according to age on tissue Doppler imaging.
abstract: OBJECTIVE
  To determine the correlation between diastolic velocities on tissue Doppler imaging and age in a sample of healthy adults and to correlate age with the velocities of transmitral and pulmonary vein flows.
  
  
  METHODS
  Echocardiographic assessment of 51 healthy individuals, whose ages ranged from 21 to 69 years. The diastolic myocardial velocities were recorded on tissue Doppler imaging. The velocities of the transmitral and pulmonary vein flows were also determined.
  
  
  RESULTS
  The initial basal septal and basal lateral diastolic myocardial velocities showed an inverse correlation with age [r = -0.40 (P = 0.004), and r = -0.60 (P = 0.0001), respectively]. The atriogenic velocities of tissue Doppler imaging correlated directly with age [r = 0.56 (P = 0.0001) in the basal septal segment, and r = 0.50 (P = 0.0001) in the basal lateral segment]. The velocities of transmitral and pulmonary vein flows also correlated with age.
  
  
  CONCLUSIONS
  Age correlates with the tissue Doppler diastolic myocardial velocities and with the velocities of transmitral and pulmonary vein flows. In healthy individuals, the parameters of left ventricular diastolic function vary with the natural evolution of age.
authors.affiliation: Instituto de Cardiologia do RS, Fundação Universitária de Cardiologia, Porto Alegre, RS, Brazil.
authors.forename: Márcia Duarte
authors.initials: MD
authors.lastname: Pedone
authors.forename: Iran
authors.initials: I
authors.lastname: Castro
authors.forename: Domingos
authors.initials: D
authors.lastname: Hatem
authors.forename: José Carlos
authors.initials: JC
authors.lastname: Haertel
authors.forename: Flávia
authors.initials: F
authors.lastname: Feier
authors.forename: Fernando
authors.initials: F
authors.lastname: Pandolfo
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001783:Blood Flow Velocity; D003971:Diastole; D015150:Echocardiography, Doppler / Q000379:methods*; D005260:Female; D006801:Humans; D008168:Lung / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*