title: A rare case of pregnancy and delivery of a healthy neonate by a woman with microprolactinoma and review of the literature.
abstract: A rare case of a term-pregnancy and delivery in a patient with microprolactinoma is presented. The patient had been treated with bromocriptine since she was 17 due to primary amenorrhea for 60 months with short intervals. Pharmacological tests with dopamine antagonists and X-ray diagnostics revealed the presence of microprolactinoma. The patient was constantly under specialist endocrinological care and the level of prolactin in her blood serum was continuously being monitored. After getting pregnant she was placed under strict gynecological scrutiny with special attention devoted to the developing fetus and possible congenital defects. The patient continued receiving bromocriptine therapy up to the 16th week of pregnancy. In the course of pregnancy in the 26th week, a circular suture was placed on the uterine cervix due to symptoms of isthmus-cervical insufficiency. In the 38th week of pregnancy a cesarean (C) section was performed and a healthy child in good general condition (Apgar score 10) was born. The child weighed 2,900 grams.
authors.affiliation: Department of Obstetrics and Gynecology, University of Medicine, Lublin, Poland.
authors.forename: A
authors.initials: A
authors.lastname: Kwaśniewska
authors.forename: M
authors.initials: M
authors.lastname: Skoczyński
authors.forename: M
authors.initials: M
authors.lastname: Semczuk
mesh_terms: D000328:Adult; D001971:Bromocriptine / Q000627:therapeutic use; D005260:Female; D006727:Hormone Antagonists / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000188:drug therapy; D011374:Progesterone / Q000097:blood; D015175:Prolactinoma / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D006727:Hormone Antagonists; D001971:Bromocriptine; D011374:Progesterone