Hemochromatosis mutations in Iranians with hepatitis B virus infection.
In this study, the frequencies of the common hemochromatosis gene mutations were assessed in 75 Iranian subjects with chronic hepatitis B infection. We found that the major C282Y mutation was significantly more frequent in subjects infected with hepatitis B virus (4%) than in 194 control subjects (0%, P=.02; Fisher's exact test).
Sendi
Hossein
H
Research Center for Gastroenterology and Liver Diseases, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.
Ghaziani
Tahereh
T
Zali
Mohammad R
MR
Adibi
Peyman
P
Agah
Mohammadreza
M
Jazayeri
Maryam
M
Shahraz
Saeed
S
Magnius
Lars
L
Bonkovsky
Herbert L
HL
D000328:Adult; D005260:Female; D020022:Genetic Predisposition to Disease; D006432:Hemochromatosis / Q000150:complications* / Q000235:genetics*; D000071020:Hemochromatosis Protein; D019694:Hepatitis B, Chronic / Q000150:complications* / Q000235:genetics; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006801:Humans; D007492:Iran; D008297:Male; D008565:Membrane Proteins / Q000235:genetics*; D009154:Mutation / Q000235:genetics*
C103673:HFE protein, human; D000071020:Hemochromatosis Protein; D015395:Histocompatibility Antigens Class I; D008565:Membrane Proteins