BODIL: a molecular modeling environment for structure-function analysis and drug design.
BODIL is a molecular modeling environment geared to help the user to quickly identify key features of proteins critical to molecular recognition, especially (1) in drug discovery applications, and (2) to understand the structural basis for function. The program incorporates state-of-the-art graphics, sequence and structural alignment methods, among other capabilities needed in modern structure-function-drug target research. BODIL has a flexible design that allows on-the-fly incorporation of new modules, has intelligent memory management, and fast multi-view graphics. A beta version of BODIL and an accompanying tutorial are available at http://www.abo.fi/fak/mnf/bkf/research/johnson/bodil.html.
Lehtonen
Jukka V
JV
Department of Biochemistry and Pharmacy, Abo Akademi University, Tykistökatu 6A, FIN-20520 Turku, Finland.
Still
Dan-Johan
DJ
Rantanen
Ville-V
VV
Ekholm
Jan
J
Björklund
Dag
D
Iftikhar
Zuhair
Z
Huhtala
Mikko
M
Repo
Susanna
S
Jussila
Antti
A
Jaakkola
Jussi
J
Pentikäinen
Olli
O
Nyrönen
Tommi
T
Salminen
Tiina
T
Gyllenberg
Mats
M
Johnson
Mark S
MS
D000465:Algorithms; D003196:Computer Graphics; D003198:Computer Simulation; D015195:Drug Design; D008958:Models, Molecular; D011487:Protein Conformation; D016415:Sequence Alignment / Q000706:statistics & numerical data; D012984:Software; D055672:Static Electricity; D013329:Structure-Activity Relationship