Atomic absorption spectroscopy in ion channel screening.
This article examines the utility of atomic absorption spectroscopy, in conjunction with cold flux assays, to ion channel screening. The multiplicity of ion channels that can be interrogated using cold flux assays and atomic absorption spectroscopy is summarized. The importance of atomic absorption spectroscopy as a screening tool is further elaborated upon by providing examples of the relevance of ion channels to various physiological processes and targeted diseases.
Stankovich
Larisa
L
Aurora Biomed Inc., 1001 East Pender Street, Vancouver, BC, Canada V6A 1W2. larisa@aurorabiomed.com
Wicks
David
D
Despotovski
Sasko
S
Liang
Dong
D
D000818:Animals; D004353:Drug Evaluation, Preclinical / Q000379:methods / Q000639:trends; D006801:Humans; D007473:Ion Channels / Q000502:physiology*; D013054:Spectrophotometry, Atomic / Q000379:methods*
D007473:Ion Channels