Synthesis and antioxidant activity of olivil-type lignans.
Olivil-type lignans, an enantiomeric type of natural olivil, were synthesized for the first time to evaluate the relationship between the structure of olivil and its antioxidant activity. A comparison of the antioxidant activity with that of other synthesized tetrahydrofuran lignans indicated reduced activity with the tertiary hydroxy group. A different effect of the two phenolic groups of olivil on the antioxidant activity was also observed.
Yamauchi
Satoshi
S
Faculty of Agriculture, Ehime University, Ehime, Japan. syamauch@agr.ehime-u.ac.jp
Hayashi
Yoshimasa
Y
Kirikihira
Takuya
T
Masuda
Toshiya
T
D000975:Antioxidants / Q000138:chemical synthesis* / Q000494:pharmacology*; D017705:Lignans / Q000138:chemical synthesis* / Q000494:pharmacology*; D015394:Molecular Structure
D000975:Antioxidants; D017705:Lignans; C476392:olivil