Thyrotoxic periodic paralysis complicated by near-fatal ventricular arrhythmias.
A 35-year-old Chinese man presented with acute thyrotoxic periodic paralysis complicated by near-fatal cardiac arrhythmias due to persistent hypokalaemia, despite maximum potassium supplementation. He was eventually resuscitated with external cadioversion. In this unusual case of severe refractory hypokalaemia leading to ventricular fibrillation in a patient with underlying thyrotoxicosis, the potential dangers concerning the use of dextrose infusion and beta-adrenergic agent for resuscitation are highlighted.
Loh
K C
KC
Loh Keh Chuan Diabetes Thyroid and Hormone Clinic, Mount Elizabeth Medical Centre, Singapore 228510. lohkc@endocrinology.com.sg
Pinheiro
L
L
Ng
K S
KS
D000328:Adult; D013956:Antithyroid Agents / Q000008:administration & dosage; D005947:Glucose / Q000009:adverse effects; D006801:Humans; D020514:Hypokalemic Periodic Paralysis / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D011441:Propylthiouracil / Q000008:administration & dosage; D013549:Sweetening Agents / Q000009:adverse effects; D013971:Thyrotoxicosis / Q000150:complications* / Q000188:drug therapy; D014693:Ventricular Fibrillation / Q000188:drug therapy / Q000209:etiology*
D013956:Antithyroid Agents; D013549:Sweetening Agents; D011441:Propylthiouracil; D005947:Glucose