title: An efficient asymmetric synthesis of (S)-atenolol: using hydrolytic kinetic resolution.
abstract: Enantiomerically pure (S)-atenolol was prepared by using (R,R) salen Co(III) complex for the resolution of terminal epoxide. This process was carried out at room temperature in excellent enantio selectivity. The method can be applied for large-scale preparation of (S)-atenolol without any problem.
authors.affiliation: Division of Organic Chemistry, Fine Chemicals Laboratory, Indian Institute of Chemical Technology, Hyderabad 500 007, India. vnakkirala2001@yahoo.com
authors.forename: D Subhas
authors.initials: DS
authors.lastname: Bose
authors.forename: A
authors.initials: A
authors.lastname: Venkat Narsaiah
mesh_terms: D001262:Atenolol / Q000138:chemical synthesis*; D006868:Hydrolysis; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D021241:Spectrometry, Mass, Electrospray Ionization; D013237:Stereoisomerism
chemical_list: D001262:Atenolol