Cytomegalovirus and Clostridium Difficile co-infection in severe ulcero-hemorrhagic colitis during induction chemotherapy for acute lymphoblastic leukemia.
Here we describe the first case of a biopsy-proven Cytomegalovirus ulcero-hemorrhagic colitis, associated with Clostridium Difficile co-infection, occurring during standard induction chemotherapy for common B cell acute lymphoblastic leukemia. We discuss the case and focalize clinical management and diagnostic issues arising from it.
Riva
Giovanni
G
Department of Oncology and Hematology, University of Modena and Reggio Emilia, Italy.
Luppi
Mario
M
Potenza
Leonardo
L
Morselli
Monica
M
Ferrari
Angela
A
Saviola
Alessia
A
Volzone
Francesco
F
Imovilli
Annalisa
A
Merighi
Alberto
A
Maiorana
Antonio
A
Torelli
Giuseppe
G
D000328:Adult; D016360:Clostridioides difficile / Q000302:isolation & purification; D003093:Colitis, Ulcerative / Q000382:microbiology* / Q000473:pathology / Q000821:virology*; D003587:Cytomegalovirus / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000473:pathology*; D004761:Enterocolitis, Pseudomembranous / Q000473:pathology*; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*