title: [Chemical analysis of bronchoalveolar lavage in diagnostics of pneumonia].
abstract: Samples of bronchoalveolar lavages, obtained from 182 patients hospitalised at Vseobecna fakultni nemocnice and Nemocnice Kralovske Vinohrady, Prague, were analysed using solid phase microextraction-gas chromatography. At least 9 %, using less strong criteria up to 20 % of samples, contained higher volatile fatty acids (VFA), indicating the presence of fermenting anaerobic bacteria, found neither by cultivation nor by microscopy. Further compounds appeared in most of chromatographic examinations, tentatively labelled as "alcohol" and "acetoin". The second one occurred almost solely in samples from patients receiving the intensive care including mechanical ventilation. If characterised more precisely, it may serve as a potential marker of patients' status.
authors.affiliation: Institute of Imunology and Microbiology, First Faculty of Medicine, Charles University, Prague, Czech Republic. jaroslav.julak@lf1.cuni.cz
authors.forename: Jaroslav
authors.initials: J
authors.lastname: Julák
authors.forename: Eva
authors.initials: E
authors.lastname: Stránská
authors.forename: Vlasta
authors.initials: V
authors.lastname: Rosová
authors.forename: Alena
authors.initials: A
authors.lastname: Dohnalová
mesh_terms: D015415:Biomarkers / Q000032:analysis; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry*; D002849:Chromatography, Gas; D005232:Fatty Acids, Volatile / Q000032:analysis; D006801:Humans; D018410:Pneumonia, Bacterial / Q000175:diagnosis*
chemical_list: D015415:Biomarkers; D005232:Fatty Acids, Volatile