title: Initial experience using the NuMED Cheatham Platinum (CP) stent for interventional treatment of coarctation of the aorta in children and adolescents.
abstract: We report the immediate results in a group of selected patients with native or recurrent coarctation of the aorta who underwent endovascular stent implantation using the newly designed Cheatham-Platinum (CP)-stent. The balloon-expandable stents were implanted in 6 patients (mean age 12.7 years) with coarctation of the aorta (5 native, 1 recurrent). The maximal systolic peak pressure gradient was decreased from 49 to 3 mmHg (p <0.001). There was a 350% increase in the mean diameter at the original coarctation site (3.8 to 13.8 mm, p <0.01). Although the maximal diameter varied from 8 to 18 mm, there was only a minor reduction in the length of the CP-stents used (max. 11%). The dilatation was successful in all patients and there were no complications during balloon dilatation or stent implantation. All patients were hypertensive prior to stent implantation, with three of them requiring antihypertensive drug therapy. In 2 patients only a moderate dilatation diameter was chosen initially due to the extremely small coarctation site (1 mm) and repeat dilatation after 12 months was performed in order to obtain a maximal aortic diameter. At a mean of 18 months of follow-up, 5 of 6 patients are normotensive. There is no recurrence of coarctation, aortic dissection or aneurysm formation and no stent displacement. These findings suggest that the implantation of CP-stents for coarctation of the aortamay cover a wide spectrum of aortic diameters and consequently hereby offer an effective alternative approach to surgery or ballon dilatation alone even in infancy and childhood. The potential for redilatation of CP-stents in a wide range of diameters without significant shortening adds to the benefit of this device in growing children.
authors.affiliation: Paediatric Intensive Care Unit, The Prince Charles Hospital, Brisbane Rode Raod, Chermside Old 4032, Austria. nikolaus_haas@health.qld.gov.au
authors.forename: N A
authors.initials: NA
authors.lastname: Haas
authors.forename: M A G
authors.initials: MA
authors.lastname: Lewin
authors.forename: W
authors.initials: W
authors.lastname: Knirsch
authors.forename: R
authors.initials: R
authors.lastname: Nossal
authors.forename: V
authors.initials: V
authors.lastname: Ocker
authors.forename: F
authors.initials: F
authors.lastname: Uhlemann
mesh_terms: D000293:Adolescent; D001017:Aortic Coarctation / Q000000981:diagnostic imaging / Q000628:therapy*; D001027:Aortography; D002404:Catheterization; D002648:Child; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D010984:Platinum; D011474:Prosthesis Design; D019233:Retreatment; D015607:Stents; D016896:Treatment Outcome
chemical_list: D010984:Platinum