title: Systematic radical gastrectomy and D2 lymphadenectomy in primary gastric B cell lymphoma: impact on diagnosis, classification and long term results. A prospective study.
abstract: The role of surgery in the treatment of primary gastric lymphoma has been recently re-evaluated. We report the results of a series of 37 operated patients for primary gastric lymphoma (PGL). All patients underwent gastrectomy with D2 lymphadenectony and bilateral liver biopsies. Postoperative histopathological classification was compared to preoperative staging data. No mortality and low morbidity were observed in this series of patients. We found a high incidence of mixed grading of tumors and a relatively high incidence of lymph node metastases in low grade lymphoma. Relying on preoperative biopsies and imaging techniques could lead to preoperative staging inaccuracy and therefore to inappropriate treatment planning. For these reasons we advocate systematic primary surgery in PGL. Surgery could be useful for staging purposes and seems to be curative in stage IE.
authors.affiliation: Istituto Dipartimentalizzato di Chirurgia d'Urgenza e di Pronto Soccorso, Cattedra di Chirurgia d'Urgenza II, Università di Roma" La Sapienza"-Viale del Policlinico - 00161 - Roma, Italy. roberto.caronna@uniroma1.it
authors.forename: R
authors.initials: R
authors.lastname: Caronna
authors.forename: M
authors.initials: M
authors.lastname: Cardi
authors.forename: M
authors.initials: M
authors.lastname: Martelli
authors.forename: E
authors.initials: E
authors.lastname: Finolezzi
authors.forename: F
authors.initials: F
authors.lastname: Natalino
authors.forename: P
authors.initials: P
authors.lastname: Mingazzini
authors.forename: S
authors.initials: S
authors.lastname: Scozzafava
authors.forename: S
authors.initials: S
authors.lastname: Mangioni
authors.forename: B G
authors.initials: BG
authors.lastname: Romeo
authors.forename: E
authors.initials: E
authors.lastname: Tarantino
authors.forename: M
authors.initials: M
authors.lastname: Benedetti
authors.forename: G
authors.initials: G
authors.lastname: Pittau
authors.forename: M
authors.initials: M
authors.lastname: Schiratti
authors.forename: P
authors.initials: P
authors.lastname: Chirletti
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods*; D016393:Lymphoma, B-Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011446:Prospective Studies; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*