title: [Differential clinical diagnostic parameters of acute hepatitis B and flare of chronic HBV infection].
abstract: OBJECTIVE
  To evaluate useful clinical diagnostic parameters for differentiating acute hepatitis B and flare of chronic HBV infection.
  
  
  METHODS
  Using PCR method to detect viral level in the patient's serum, HBV marker was detected by ELISA kit. Liver function was also detected.
  
  
  RESULTS
  The patient can be diagnosed as acute hepatitis B if a patient has one of the following parameters: (1)HBV-DNA negative on admission. (2) When the patient's ALT was lower than 400 IU/L, HBV-DNA was negative or HBsAg became negative or HBeAg/HBeAb seroconverted.
  
  
  CONCLUSIONS
  The viral DNA level, HBV marker and ALT can help differentiate acute hepatitis B and flare of chronic HBV infection.
authors.affiliation: Department of Infectious Diseases, The First Teaching Hospital of Beijing University, Beijing 100034, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Zhao
authors.forename: Geng-shan
authors.initials: GS
authors.lastname: Tian
mesh_terms: D000208:Acute Disease; D000328:Adult; D000410:Alanine Transaminase / Q000097:blood*; D004279:DNA, Viral / Q000097:blood*; D003937:Diagnosis, Differential; D006509:Hepatitis B / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D006510:Hepatitis B Antibodies / Q000097:blood; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006513:Hepatitis B e Antigens / Q000097:blood; D019694:Hepatitis B, Chronic / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D008111:Liver Function Tests; D008875:Middle Aged
chemical_list: D004279:DNA, Viral; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens; D000410:Alanine Transaminase