title: Metabolic evaluation of urolithiasis patients from eastern Croatia.
abstract: Metabolic parameters were determined in fasting blood serum, fasting first morning urine, and 24-hour urine of male patients with recurrent calcium oxalate stones (N = 26, age 39.1 +/- 6.2 years) as well as in male healthy controls (N = 18, age 35.0 +/- 7.1 years), recruited from the eastern part of Croatia. The 24-hour urinary calcium excretion was significantly higher (p < 0.01) for patients (5.6 +/- 2.5 mmol) than for controls (3.7 +/- 1.9 mmol), but potassium excretion was higher (p < 0.01) for controls (74.5 +/- 33.8 mmol) than for patients (49.2 +/- 15.7 mmol). The mean ionic activity product of calcium and oxalate ions, IAP(CaOx), calculated from the fasting first morning urine parameters, was 25% higher for patients than for controls, but the difference was not statistically significant (p > 0.05). Very strong correlation (r = 0.97) was obtained between IAP(CaOx) values and calculated Ogawa indices that were recommended for estimating the potential risk for calcium oxalate stone formation.
authors.affiliation: Institute "Ruder Bosković", Zagreb, Croatia.
authors.forename: Vesna
authors.initials: V
authors.lastname: Babić-Ivancić
authors.forename: Selma Cvijetić
authors.initials: SC
authors.lastname: Avdagić
authors.forename: Vatroslav
authors.initials: V
authors.lastname: Serić
authors.forename: Jasminka
authors.initials: J
authors.lastname: Kontrec
authors.forename: Antun
authors.initials: A
authors.lastname: Tucak
authors.forename: Helga
authors.initials: H
authors.lastname: Füredi-Milhofer
authors.forename: Milenko
authors.initials: M
authors.lastname: Marković
mesh_terms: D000328:Adult; D002118:Calcium / Q000652:urine*; D002129:Calcium Oxalate / Q000652:urine*; D016022:Case-Control Studies; D017523:Croatia; D006801:Humans; D008297:Male; D011188:Potassium / Q000652:urine; D012008:Recurrence; D012307:Risk Factors; D016482:Urinalysis; D014545:Urinary Calculi / Q000503:physiopathology*
chemical_list: D002129:Calcium Oxalate; D011188:Potassium; D002118:Calcium