title: Novel avian influenza H7N3 strain outbreak, British Columbia.
abstract: Genome sequences of chicken (low pathogenic avian influenza [LPAI] and highly pathogenic avian influenza [HPAI]) and human isolates from a 2004 outbreak of H7N3 avian influenza in Canada showed a novel insertion in the HA0 cleavage site of the human and HPAI isolate. This insertion likely occurred by recombination between the hemagglutination and matrix genes in the LPAI virus.
authors.affiliation: British Columbia Cancer Agency (BCCA) Genome Sciences Centre, Vancouver, British Columbia, Canada.
authors.forename: Martin
authors.initials: M
authors.lastname: Hirst
authors.forename: Caroline R
authors.initials: CR
authors.lastname: Astell
authors.forename: Malachi
authors.initials: M
authors.lastname: Griffith
authors.forename: Shaun M
authors.initials: SM
authors.lastname: Coughlin
authors.forename: Michelle
authors.initials: M
authors.lastname: Moksa
authors.forename: Thomas
authors.initials: T
authors.lastname: Zeng
authors.forename: Duane E
authors.initials: DE
authors.lastname: Smailus
authors.forename: Robert A
authors.initials: RA
authors.lastname: Holt
authors.forename: Steven
authors.initials: S
authors.lastname: Jones
authors.forename: Marco A
authors.initials: MA
authors.lastname: Marra
authors.forename: Martin
authors.initials: M
authors.lastname: Petric
authors.forename: Mel
authors.initials: M
authors.lastname: Krajden
authors.forename: David
authors.initials: D
authors.lastname: Lawrence
authors.forename: Annie
authors.initials: A
authors.lastname: Mak
authors.forename: Ron
authors.initials: R
authors.lastname: Chow
authors.forename: Danuta M
authors.initials: DM
authors.lastname: Skowronski
authors.forename: S Aleina
authors.initials: SA
authors.lastname: Tweed
authors.forename: SweeHan
authors.initials: S
authors.lastname: Goh
authors.forename: Robert C
authors.initials: RC
authors.lastname: Brunham
authors.forename: John
authors.initials: J
authors.lastname: Robinson
authors.forename: Victoria
authors.initials: V
authors.lastname: Bowes
authors.forename: Ken
authors.initials: K
authors.lastname: Sojonky
authors.forename: Sean K
authors.initials: SK
authors.lastname: Byrne
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Darwyn
authors.initials: D
authors.lastname: Kobasa
authors.forename: Tim
authors.initials: T
authors.lastname: Booth
authors.forename: Mark
authors.initials: M
authors.lastname: Paetzel
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001955:British Columbia / Q000453:epidemiology; D002645:Chickens; D004196:Disease Outbreaks / Q000662:veterinary*; D006801:Humans; D009980:Influenza A virus / Q000235:genetics* / Q000472:pathogenicity; D005585:Influenza in Birds / Q000453:epidemiology* / Q000821:virology; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016254:Mutagenesis, Insertional; D011487:Protein Conformation; D016415:Sequence Alignment; D014764:Viral Proteins / Q000737:chemistry
chemical_list: D014764:Viral Proteins