A new type of erythrokeratoderma.
We describe a Dutch man suffering from a previously undescribed erythrokeratoderma associated with palmoplantar keratoderma and circular constrictions of the fingers. No mutations were identified in the genes encoding loricrin, connexin 26, 30, 30.3, 31 and 31.1, and ARS/complex B. There are some similarities between the disorder described here and other palmoplantar keratodermas and erythrokeratodermas, but assignment to a particular disease category is not possible. Hence we propose that we have delineated a novel type of keratoderma.
van Steensel
M A M
MA
Department of Dermatology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, the Netherlands. mvst@sder.azm.nl
van Geel
M
M
Steijlen
P M
PM
D000328:Adult; D001132:Arm; D003873:Dermatitis, Exfoliative / Q000473:pathology*; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000473:pathology; D007642:Keratosis / Q000473:pathology*; D007868:Leg Dermatoses / Q000473:pathology; D008297:Male