Intramuscular ziprasidone in youth: a retrospective chart review.
OBJECTIVE
The aim of this study was to assess the tolerability and effectiveness of intramuscular ziprasidone in inpatient children and adolescents.


METHODS
A retrospective chart review was conducted of child and adolescent inpatients at a private psychiatric hospital in central New York between January 1, 2003 and August 30, 2003. Subjects who had received intramuscular ziprasidone were identified, and their age, gender, and dosage were recorded. Nursing-shift notes were reviewed to ascertain the need for repeat injection and for adverse reactions.


RESULTS
Forty-nine youths received intramuscular ziprasidone; 43 injections were 20 mg and 6 injections were 10 mg. Readministration within 4 hours was required in only 1 subject. No adverse events were recorded.


CONCLUSIONS
Intramuscular ziprasidone was well tolerated and effective for acutely agitated and aggressive inpatient youth.
Staller
Jud A
JA
Department of Psychiatry, SUNY Upstate Medical University, Syracuse, New York 13210, USA. stallerj@upstate.edu
D000293:Adolescent; D000374:Aggression / Q000187:drug effects*; D014150:Antipsychotic Agents / Q000008:administration & dosage*; D002648:Child; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D010879:Piperazines / Q000008:administration & dosage*; D011595:Psychomotor Agitation / Q000188:drug therapy*; D011618:Psychotic Disorders / Q000188:drug therapy*; D012189:Retrospective Studies; D013844:Thiazoles / Q000008:administration & dosage*; D016896:Treatment Outcome
D014150:Antipsychotic Agents; D010879:Piperazines; D013844:Thiazoles; C092292:ziprasidone