title: Virulence of the nine serovar reference strains of Haemophilus paragallinarum.
abstract: The virulence of the reference strains of the nine currently recognized Kume serovars of Haemophilus paragallinarum was investigated. The capacity of the H. paragallinarum strains to cause the typical clinical signs of upper respiratory tract disease associated with infectious coryza in unvaccinated, nasal-challenged chickens was assessed. Differences in virulence were assessed by means of a standardized scoring system for clinical signs. All nine strains were pathogenic to chickens, producing typical clinical signs of infectious coryza. The highest clinical signs score was obtained for serovar C-1 (1.72), while the lowest clinical signs score was obtained for serovar C-4 (0.32). Our results indicate that virulence differences exist among the serovars of H. paragallinarum.
authors.affiliation: Centro de Investigación y Estudios Avanzados en Salud Animal, Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Instituto Literario No. 100, Col. Centro, Toluca, 50000, México.
authors.forename: V E
authors.initials: VE
authors.lastname: Soriano
authors.forename: G M
authors.initials: GM
authors.lastname: Longinos
authors.forename: R P
authors.initials: RP
authors.lastname: Fernández
authors.forename: Q E
authors.initials: QE
authors.lastname: Velásquez
authors.forename: C A
authors.initials: CA
authors.lastname: Ciprián
authors.forename: F
authors.initials: F
authors.lastname: Salazar-García
authors.forename: P J
authors.initials: PJ
authors.lastname: Blackall
mesh_terms: D000818:Animals; D002645:Chickens / Q000382:microbiology*; D006192:Haemophilus Infections / Q000382:microbiology / Q000662:veterinary*; D044134:Haemophilus paragallinarum / Q000145:classification / Q000472:pathogenicity*; D011201:Poultry Diseases / Q000382:microbiology*; D012140:Respiratory Tract Diseases / Q000382:microbiology / Q000662:veterinary*; D012703:Serotyping / Q000662:veterinary; D013047:Specific Pathogen-Free Organisms; D014774:Virulence / Q000502:physiology