Proteomic analysis of Korean ginseng (Panax ginseng C.A. Meyer).
Although many reports have been published regarding the pharmacological effects of ginseng, little is known about the biochemical pathways operant in ginsenoside biosynthesis, or the genes involved therein. Proteomics analysis is an approach to elucidate the physiological characteristics and biosynthetic pathways of ginsenosides, main components of ginseng. In this review, we introduced the recent progress in proteomics studies of ginseng (Panax ginseng C.A. Meyer). We briefly reference the genomic analyses of P. ginseng, without which proteomics approaches would have been impossible. Functional genomics studies regarding secondary metabolism in P. ginseng are also introduced here, in order to introduce possible future prospects for further study.
Nam
Myung Hee
MH
Metabolome Analysis Team, Korea Basic Science Institute, Seoul 136-701, Korea.
Kim
Seung Il
SI
Liu
Jang Ryol
JR
Yang
Deok Chun
DC
Lim
Yong Pyo
YP
Kwon
Kyung-Hoon
KH
Yoo
Jong Shin
JS
Park
Young Mok
YM
D030541:Databases, Genetic; D015180:Electrophoresis, Gel, Two-Dimensional / Q000379:methods; D020224:Expressed Sequence Tags; D020869:Gene Expression Profiling; D018745:Genome, Plant; D020411:Oligonucleotide Array Sequence Analysis; D005894:Panax / Q000737:chemistry* / Q000235:genetics* / Q000378:metabolism; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics*; D040901:Proteomics / Q000379:methods*
D010940:Plant Proteins