title: Antimicrobial activity and chemical investigation of Brazilian Drosera.
abstract: The antimicrobial activity of three different extracts (hexanic, ethyl acetate, methanol) obtained from Brazilian Drosera species (D. communis, D. montana var. montana, D. brevifolia, D. villosa var. graomogolensis, D. villosa var. villosa, Drosera sp. 1, and Drosera sp. 2 ) were tested against Staphylococcus aureus (ATCC 25923), Enterococcus faecium (ATCC23212), Pseudomonas aeruginosa (ATCC27853), Escherichia coli (ATCC11229), Salmonella choleraesuis (ATCC10708), Klebsiella pneumoniae (ATCC13883), and Candida albicans (a human isolate). Better antimicrobial activity was observed with D. communis and D. montana var. montana ethyl acetate extracts. Phytochemical analyses from D. communis, D. montana var. montana and D. brevifolia yielded 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin); long chain aliphatic hydrocarbons were isolated from D. communis and from D. villosa var. villosa, a mixture of long chain aliphatic alcohols and carboxylic acids, was isolated from D. communis and 3b-O-acetylaleuritolic acid from D. villosa var. villosa.
authors.affiliation: Departamento de Química, Centro de Ciências Exatas, Universidade Estadual de Londrina, Caixa Postal 6001, 86051-970 Londrina, PR, Brazil. dalva@uel.br
authors.forename: Dalva Trevisan
authors.initials: DT
authors.lastname: Ferreira
authors.forename: César Cornélio
authors.initials: CC
authors.lastname: Andrei
authors.forename: Halha Ostrensky
authors.initials: HO
authors.lastname: Saridakis
authors.forename: Terezinha de Jesus
authors.initials: Tde J
authors.lastname: Faria
authors.forename: Elisângela
authors.initials: E
authors.lastname: Vinhato
authors.forename: Kátia Eliane
authors.initials: KE
authors.lastname: Carvalho
authors.forename: Juliana Feijó Souza
authors.initials: JF
authors.lastname: Daniel
authors.forename: Sílvio Luiz
authors.initials: SL
authors.lastname: Machado
authors.forename: Dennis Panayotis
authors.initials: DP
authors.lastname: Saridakis
authors.forename: Raimundo
authors.initials: R
authors.lastname: Braz-Filho
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects; D029787:Drosera / Q000737:chemistry*; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts