title: Colorectal carcinoma in children, adolescents, and young adults.
abstract: The authors conducted a retrospective evaluation of patients younger than 30 years with colorectal carcinoma in Argentina. Patients were divided into group 1 (patients treated at pediatric institutions from 0 to 20 years of age, n = 14) and group 2 (patients from 21 to 30, n = 7, treated at adult centers). Group 1 had significantly more advanced disease and a poorer prognosis. Six patients (2/14 in group 1 and 4/7 in group 2) survive disease-free. Thirteen patients died of progressive disease, 1 died of a non-tumor-related cause, and 1 is still on treatment. Patients younger than 20 years have a poorer prognosis, probably because of advanced disease on presentation.
authors.affiliation: Hospital J. P. Garrahan, Buenos Aires, Argentina.
authors.forename: Guillermo L
authors.initials: GL
authors.lastname: Chantada
authors.forename: Viviana B
authors.initials: VB
authors.lastname: Perelli
authors.forename: Mercedes García
authors.initials: MG
authors.lastname: Lombardi
authors.forename: Diego
authors.initials: D
authors.lastname: Amaral
authors.forename: Diana
authors.initials: D
authors.lastname: Cascallar
authors.forename: Marcelo
authors.initials: M
authors.lastname: Scopinaro
authors.forename: Ernesto Gil
authors.initials: EG
authors.lastname: Deza
authors.forename: Felipe Gustavo
authors.initials: FG
authors.lastname: Gercovich
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D015179:Colorectal Neoplasms / Q000401:mortality* / Q000503:physiopathology* / Q000628:therapy*; D013505:Digestive System Surgical Procedures; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome