title: Selective generation of gut-tropic T cells in gut-associated lymphoid tissues: requirement for GALT dendritic cells and adjuvant.
abstract: To gain entry into peripheral tissues, effector T lymphocytes express specific combinations of adhesion molecules and chemokine receptors. Expression of these are induced during activation in regional secondary lymphoid organs. Herein, we describe a role for GALT DCs in the generation of CCR9(+) alpha(4)beta(7)(+) gut tropic lymphocytes.
authors.affiliation: Immunology Section, Lund University, BMC I-13, S-22184 Lund, Sweden. Marcus.Svensson@immuno.lu.se
authors.forename: Marcus
authors.initials: M
authors.lastname: Svensson
authors.forename: Bengt
authors.initials: B
authors.lastname: Johansson-Lindbom
authors.forename: Marc-André
authors.initials: MA
authors.lastname: Wurbel
authors.forename: Bernard
authors.initials: B
authors.lastname: Malissen
authors.forename: Gabriel
authors.initials: G
authors.lastname: Márquez
authors.forename: William
authors.initials: W
authors.lastname: Agace
mesh_terms: D000818:Animals; D000938:Antigen-Presenting Cells / Q000276:immunology; D018925:Chemokines / Q000276:immunology; D003713:Dendritic Cells / Q000276:immunology*; D006801:Humans; D018928:Immunity, Mucosal; D007249:Inflammation / Q000276:immunology; D007413:Intestinal Mucosa / Q000276:immunology*; D008221:Lymphoid Tissue / Q000276:immunology; D016201:Receptors, Lymphocyte Homing / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D018925:Chemokines; D016201:Receptors, Lymphocyte Homing