title: Hypophysial transposition (hypophysopexy) for radiosurgical treatment of pituitary tumors involving the cavernous sinus. Technical note.
abstract: Stereotactic radiosurgery (SRS) is performed with increasing frequency in the treatment of residual or recurrent pituitary adenomas. Its major associated risk in these cases of residual or recurrent pituitary tumor adjacent to normal functional pituitary gland is radiation exposure to the pituitary, which frequently leads to the development of hypopituitarism. The authors describe a technique of pituitary transposition to reduce the radiation dose to the normal pituitary gland in cases of planned radiosurgical treatment of residual pituitary adenoma within the cavernous sinus. A sellar exploration for tumor resection is performed, the pituitary gland is transposed from the region of the cavernous sinus, and a fat and fascia graft is interposed between the normal pituitary gland and the residual tumor in the cavernous sinus. The residual tumor may then be treated with SRS. The increased distance between the normal pituitary gland and the residual tumor facilitates treatment of the tumor with radiosurgery and reduces radiation exposure to the normal pituitary gland.
authors.affiliation: Department of Neurosurgery, University of Utah, Salt Lake City, Utah 84132-2303, USA.
authors.forename: James K
authors.initials: JK
authors.lastname: Liu
authors.forename: Meic H
authors.initials: MH
authors.lastname: Schmidt
authors.forename: Joel D
authors.initials: JD
authors.lastname: MacDonald
authors.forename: Randy L
authors.initials: RL
authors.lastname: Jensen
authors.forename: William T
authors.initials: WT
authors.lastname: Couldwell
mesh_terms: D000293:Adolescent; D000328:Adult; D002426:Cavernous Sinus / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D006801:Humans; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D011859:Radiography; D016634:Radiosurgery / Q000379:methods*