Morphological differences among cavum septi pellucidi obtained in patients with schizophrenia and healthy individuals: forensic implications. A post-mortem study.
Cavum septi pellucidi (CSP), especially when longer than 6 mm, has been recognized as a neurodevelopmental anomaly associated with schizophrenia. The present post-mortem study was designed to determine the importance of linear parameters of CSP and to evaluate the possible differences of CSP in schizophrenic patients (n=25 out of 110 CSP+ brains) and normal persons (n=40 out of 110 CSP+ brains). According to our results, schizophrenia patients had significantly longer and wider CSP than normal individuals. Also, statistical analysis revealed a higher suicide rate in CSP-positive patients with schizophrenia.
Filipović
Branislav
B
Institute of Anatomy, University of Belgrade, Belgrade, Serbia and Montenegro. filipbr@bitsyu.net
Kovacević
Slobodan
S
Stojicić
Milan
M
Prostran
Milan
M
Filipović
Branka
B
D000059:Accidents; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000437:Alcoholism / Q000473:pathology; D001921:Brain / Q000473:pathology; D020208:Brain Injury, Chronic / Q000473:pathology; D002423:Cause of Death; D002508:Cephalometry; D003430:Cross-Sectional Studies; D005260:Female; D005554:Forensic Medicine; D006708:Homicide; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012559:Schizophrenia / Q000473:pathology*; D012688:Septum Pellucidum / Q000002:abnormalities* / Q000473:pathology*; D013405:Suicide / Q000706:statistics & numerical data; D014754:Violence