title: The failed intraperitoneal colon anastomosis after colon resection.
abstract: BACKGROUND
  The purpose of this study is to present the incidence of anastomotic leakage after colon resection and intraperitoneal anastomosis for colorectal cancer.
  
  
  METHODS
  In the last ten years, 205 patients underwent colonic resection with intraperitoneal anastomosis for colon cancer. The surgical management of colorectal cancer consisted of 66 right hemicolectomies, 3 transverse colectomies, 17 left hemicolectomies, 98 sigmoid colectomies and 21 high anterior resections of the rectum. Diagnosis of leakage was made by clinical features, blood vessel examinations and abdominal CT-scans.
  
  
  RESULTS
  Anastomotic leakage occurred in 5 out of 205 patients (2.4%). One of these patients underwent emergency surgery and the other 4 elective surgery; 3 by manual, 2 by mechanical suture. Three patients with anastomotic leakage were reoperated on days 4, 5 and 7, and 2 patients were treated conservatively. Two of the patients (20%) with anastomotic leakage died due to sepsis.
  
  
  CONCLUSIONS
  Even though the rate of anastomotic leakage in patients with intraperitoneal anastomosis after colon resection for colorectal cancer is low, it remains a significant complication and a major cause of postoperative morbidity and mortality.
authors.affiliation: 4th Surgical Department, Aristotle University, Thessaloniki, Greece. ik@hol.gr
authors.forename: I
authors.initials: I
authors.lastname: Kanellos
authors.forename: K
authors.initials: K
authors.lastname: Blouhos
authors.forename: H
authors.initials: H
authors.lastname: Demetriades
authors.forename: M G
authors.initials: MG
authors.lastname: Pramateftakis
authors.forename: I
authors.initials: I
authors.lastname: Mantzoros
authors.forename: E
authors.initials: E
authors.lastname: Zacharakis
authors.forename: D
authors.initials: D
authors.lastname: Betsis
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical / Q000009:adverse effects* / Q000379:methods; D015331:Cohort Studies; D003082:Colectomy / Q000009:adverse effects* / Q000379:methods; D015179:Colorectal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D018570:Risk Assessment; D017678:Sex Distribution; D016019:Survival Analysis