title: From catastrophe to complexity: a novel model of integrative central neural regulation of effort and fatigue during exercise in humans: summary and conclusions.
abstract: It is hypothesised that physical activity is controlled by a central governor in the brain and that the human body functions as a complex system during exercise. Using feed forward control in response to afferent feedback from different physiological systems, the extent of skeletal muscle recruitment is controlled as part of a continuously altering pacing strategy, with the sensation of fatigue being the conscious interpretation of these homoeostatic, central governor control mechanisms.
authors.affiliation: Research Unit for Exercise Science and Sports Medicine, University of Cape Town, Sports Science of South Africa, PO Box 115, Newlands 7725, South Africa. tdnoakes@sports.uct.ac.za
authors.forename: T D
authors.initials: TD
authors.lastname: Noakes
authors.forename: A
authors.initials: A
authors.lastname: St Clair Gibson
authors.forename: E V
authors.initials: EV
authors.lastname: Lambert
mesh_terms: D002490:Central Nervous System / Q000502:physiology*; D004734:Energy Metabolism / Q000502:physiology; D015444:Exercise / Q000502:physiology*; D006801:Humans; D009043:Motor Activity / Q000502:physiology; D018763:Muscle Fatigue / Q000502:physiology*; D010807:Physical Endurance / Q000502:physiology; D005082:Physical Exertion / Q000502:physiology