[Risk factors for the immediate outcome of gastrointestinal bleeding in patients with cirrhosis].
The risk factors in the immediate outcome of gastrointestinal bleeding were examined in a prospective study of 134 patients with liver cirrhosis. The hemorrhagic episode has a negative prognosis in the immediate outcome (p < 0.01), recording 48 (35.82%) deaths. The deaths occurred in the acute phase of bleeding (n = 18; 13.40%), after recurrent hemorrhage (n = 24; 17.23%) and in 6 other cases (4.47%) after sclerotherapy or surgical treatment of varicosities. After varicose veins sclerotherapy (n = 8), 2 deaths were recorded and 4 other after surgery (n = 22). The advanced stage of cirrhosis, Child C stage, (n = 62) was accompanied by most of deaths (n = 38; 61.29%) (p < 0.01). Among the risk factors responsible for death, there were recorded: encephalopathy (p < 0.05), jaundice (p < 0.01), altered general status ((p < 0.01) and increased seric level of bilirubin over 3 mg% (p < 0.001). Jaundice is among the risk factors with the highest sensitivity (83.33%) and seric bilirubin over 3 mg% has the highest positive predictive value (64.28%).
Păunescu
V
V
Clinica Chirurgicală, Spitalul Clinic de Urgenţă "Bagdasar - Arseni", Bucureşti.
Grigorean
V
V
Popescu
C
C
D000368:Aged; D000465:Algorithms; D004932:Esophageal and Gastric Varices / Q000209:etiology / Q000628:therapy; D005260:Female; D005355:Fibrosis / Q000150:complications* / Q000401:mortality / Q000628:therapy; D006471:Gastrointestinal Hemorrhage / Q000209:etiology* / Q000401:mortality / Q000628:therapy; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors