title: Functional and anatomical outcome of anterior and posterior vaginal prolapse repair with prolene mesh.
abstract: OBJECTIVE
  To evaluate the effects of prolene mesh on urinary, bowel and sexual function in prolapse surgery.
  
  
  METHODS
  Prospective observational study on consecutive women.
  
  
  METHODS
  Two referral uorgynaecological units in Italy.
  
  
  METHODS
  Women requiring prolapse repair for anterior or posterior vaginal prolapse.
  
  
  METHODS
  All women were assessed for urinary, bowel, prolapse symptoms and dyspareunia pre- and post-operatively. Urodynamics was performed in selected cases. Surgery consisted of an anterior or posterior repair plus a prolene mesh. Follow up was after 1, 6 and 12 months. The ANOVA test was used for statistical analysis.
  
  
  METHODS
  Vaginal anatomical restoration, urinary, bowel and sexual function.
  
  
  RESULTS
  We recruited 63 women (mean age 63 years) with a mean follow up of 17 months. Anatomically, the success rate was 94%. Thirty-two women had an anterior repair. Among this group, the sexual activity rate did not alter but dyspareunia increased by 20%. Urge and stress incontinence did not change post-operatively but urgency improved in 10% and 13% had vaginal erosion of the mesh. Thirty-one women had a posterior repair. Among this group, sexual activity decreased by 12% and dyspareunia increased in 63%. Constipation improved in 15% and anal incontinence in 4%, and 6.5% of women had vaginal erosion of the mesh and one required mesh removal for pelvic abscess.
  
  
  CONCLUSIONS
  Although this study shows good anatomical results with the use of prolene mesh for prolapse repair, there was a high rate of morbidity. We believe that the use of prolene mesh should be abandoned.
authors.affiliation: Divisione di Ginecologia Chirurgica, Ospedale Bassini, University of Milan-Bicocca, Italy.
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Milani
authors.forename: Stefano
authors.initials: S
authors.lastname: Salvatore
authors.forename: Marco
authors.initials: M
authors.lastname: Soligo
authors.forename: Paola
authors.initials: P
authors.lastname: Pifarotti
authors.forename: Michele
authors.initials: M
authors.lastname: Meschia
authors.forename: Marina
authors.initials: M
authors.lastname: Cortese
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D003248:Constipation / Q000209:etiology; D004414:Dyspareunia / Q000209:etiology; D005242:Fecal Incontinence / Q000209:etiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D011126:Polypropylenes / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000209:etiology; D011446:Prospective Studies; D012735:Sexual Dysfunction, Physiological / Q000209:etiology; D013526:Surgical Mesh; D016896:Treatment Outcome; D014550:Urinary Incontinence, Stress / Q000209:etiology; D014596:Uterine Prolapse / Q000601:surgery*
chemical_list: D011126:Polypropylenes