title: Paraneoplastic neurologic syndrome and autoimmune Addison disease in a patient with thymoma.
abstract: A 48-year-old man with autoimmune Addison disease developed the following paraneoplastic neurologic syndromes (PNNS): limbic encephalitis, opsoclonus/myoclonus, and sensorimotor and autonomic neuropathies. An anterior mediastinal mass detected on a chest computed tomographic scan was found on resection to be a noninvasive lymphocytic thymoma. The PNNS went into remission 1 year after the thymectomy. This is the first case of thymoma associated with autoimmune Addison disease and PNNS to be described in the literature.
authors.affiliation: Department of General Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan. hmorita@cc.gifu-u.ac.jp
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Morita
authors.forename: Takuo
authors.initials: T
authors.lastname: Hirota
authors.forename: Tomoatsu
authors.initials: T
authors.lastname: Mune
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Suwa
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Ishizuka
authors.forename: Takashi
authors.initials: T
authors.lastname: Inuzuka
authors.forename: Keiko
authors.initials: K
authors.lastname: Tanaka
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Ishimori
authors.forename: Shigenori
authors.initials: S
authors.lastname: Nakamura
authors.forename: Keigo
authors.initials: K
authors.lastname: Yasuda
mesh_terms: D000224:Addison Disease / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D020361:Paraneoplastic Syndromes, Nervous System / Q000209:etiology*; D013945:Thymoma / Q000150:complications*; D013953:Thymus Neoplasms / Q000150:complications*