High-performance liquid chromatographic mass spectrometric identification of the photoproducts of cymoxanil.
The photochemical degradation of the fungicide cymoxanil {2-cyano-N-[(ethylamino)carbonyl]-2-(methoxyimino) acetamide} was studied in aqueous buffer solution (pH 5.9+/- 0.1) under UV light and in laboratory conditions. The degradation followed a pseudo- first-order kinetic with significant correlation coefficient. The main photoproducts were separated and tentatively identified by HPLC/UV and HPLC/MS data, as 3-ethyl-4-(methoxyamino)-2,5-dioxo-4-imidazolidinecarbonitrile, 1-ethyl-5-(methoxyimino)-2,4-imidazolidin-2,4-dione, ethylimidazolidinetrione and {[(ethylamino)carbonyl]-amino}oxoacetic acid. A photolysis pathway of cymoxanil is proposed.
Morrica
Patrizia
P
Dipartimento di Chimica Farmaceutica e Tossicologica, Università degli Studi di Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy. morrica@unina.it
Fidente
Paola
P
Seccia
Serenella
S
D000081:Acetamides / Q000737:chemistry* / Q000302:isolation & purification / Q000528:radiation effects; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D005659:Fungicides, Industrial / Q000737:chemistry / Q000528:radiation effects; D007700:Kinetics; D013058:Mass Spectrometry / Q000379:methods*; D010782:Photolysis; D012680:Sensitivity and Specificity; D013056:Spectrophotometry, Ultraviolet
D000081:Acetamides; D005659:Fungicides, Industrial; C025644:2-cyano-N-((ethylamino)carbonyl)-2-(methoxyimino)acetamide