title: Contrast media induces hypoperfusion in kidneys with ureteral stone: Doppler US study.
abstract: We aimed to assess the hemodynamic effects of nonionic low-osmolarity contrast media (CM) on kidneys with ureteral stone (KUS). A total of 16 patients with KUS (group A) and 25 control patients (group B) were evaluated with Doppler ultrasound (US) bilaterally for main (MRA), interlobar (ILA) and arcuate renal arteries (ARA), before and 15 min after CM for IV pyelography. Peak systolic (PSV) and end diastolic velocities (EDV) and resistance index (RI) were measured. Data were analyzed by ANOVA and t-test. In group A, CM induced increase in PSV of MRA of contralateral kidney (p = 0.021) and decrease in PSV of ILA (p = 0.024), decrease in PSV and EDV and increase in RI of ARA of KUS (p = 0.010, 0.005, 0.027, respectively). CM induced hypoperfusion in KUS and compensatory changes in contralateral kidneys, similar to the effects of diuresis or mannitol. We conclude that the effect of CM on KUS is related to its osmolar load.
authors.affiliation: Kirikkale University School of Medicine, Suleyman Demirel Hospital, Kirikkale, Turkey. birsenunal@hotmail.com
authors.forename: Birsen
authors.initials: B
authors.lastname: Unal
authors.forename: Simay
authors.initials: S
authors.lastname: Kara
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Bilgili
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity; D001794:Blood Pressure / Q000187:drug effects; D003287:Contrast Media / Q000494:pharmacology*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012077:Renal Artery / Q000000981:diagnostic imaging* / Q000503:physiopathology; D012079:Renal Circulation / Q000187:drug effects*; D018608:Ultrasonography, Doppler; D014514:Ureteral Calculi / Q000503:physiopathology*; D014567:Urography; D014655:Vascular Resistance
chemical_list: D003287:Contrast Media