title: The total synthesis of gambierol.
abstract: This communication describes the total synthesis of the marine polyether toxin, gambierol. This work couples our iterative C-glycoside/enol ether-olefin metathesis strategy to the subunits with a unique olefin metathesis/carbonyl olefination reaction to bring the subunits together.
authors.affiliation: Department of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112, USA.
authors.forename: Henry W B
authors.initials: HW
authors.lastname: Johnson
authors.forename: Utpal
authors.initials: U
authors.lastname: Majumder
authors.forename: Jon D
authors.initials: JD
authors.lastname: Rainier
mesh_terms: D000818:Animals; D002922:Ciguatoxins / Q000138:chemical synthesis*; D004141:Dinoflagellida / Q000737:chemistry; D004988:Ethers, Cyclic / Q000138:chemical synthesis*; D006027:Glycosides / Q000737:chemistry; D011083:Polycyclic Compounds / Q000138:chemical synthesis*; D035964:Oxocins
chemical_list: D002922:Ciguatoxins; D004988:Ethers, Cyclic; D006027:Glycosides; D011083:Polycyclic Compounds; C435770:gambierol; D035964:Oxocins