I(-)-catalyzed methyl-oxygen bond cleavage in 2-methoxyfurans. An efficient synthesis of butenolides.
An efficient I(-)-catalyzed methyl-oxygen bond cleavage in 2-methoxyfurans was observed. The subsequent C-C bond formation occurred at the 5-position to afford substituted butenolides. The structures of the final products were determined by the X-ray diffraction study.
Ma
Shengming
S
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, P. R. China. masm@mail.sioc.ac.cn
Lu
Lianghua
L
Lu
Ping
P
D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry; D001067:Appetite Depressants / Q000138:chemical synthesis / Q000737:chemistry; D018360:Crystallography, X-Ray; D005663:Furans / Q000737:chemistry* / Q000378:metabolism; D007166:Immunosuppressive Agents / Q000138:chemical synthesis / Q000737:chemistry; D007454:Iodides / Q000737:chemistry*
D001067:Appetite Depressants; D005663:Furans; D007166:Immunosuppressive Agents; D007454:Iodides; C004511:butenolide; D015107:4-Butyrolactone