Endoscopic resection of Peutz-Jeghers polyps throughout the small intestine at double-balloon enteroscopy without laparotomy.
BACKGROUND
Small-bowel enteroscopy with the double-balloon method was developed to improve access to the small intestine. This study evaluated the usefulness of this method for the resection of small-intestinal Peutz-Jeghers polyps.


METHODS
Two patients with Peutz-Jeghers syndrome underwent nonsurgical double-balloon enteroscopic resection of polyps throughout the small intestine.


METHODS
Multiple polyps in the jejunum were successfully resected via the oral route, as were the polyps in the ileum via the anal route. All 18 polyps (10-60 mm in size) were resected without subsequent bleeding or perforation. Histopathologically, 3 large polyps (>30 mm diameter) were hamartomas with adenomatous components.


CONCLUSIONS
Double-balloon enteroscopy was safe and useful for the diagnosis and the treatment of Peutz-Jeghers polyps throughout the small intestine. Double-balloon enteroscopic polypectomy might preclude complications of Peutz-Jeghers syndrome, including intussusception, bleeding, and tumorogenesis, thereby obviating the need for multiple laparotomies.
Ohmiya
Naoki
N
Division of Gastroenterology, Department of Therapeutic Medicine, Nagoya, Japan.
Taguchi
Ayumu
A
Shirai
Kennosuke
K
Mabuchi
Nobuyuki
N
Arakawa
Daigo
D
Kanazawa
Hironobu
H
Ozeki
Masayasu
M
Yamada
Masahiro
M
Nakamura
Masanao
M
Itoh
Akihiro
A
Hirooka
Yoshiki
Y
Niwa
Yasumasa
Y
Nagasaka
Tetsuro
T
Ito
Masafumi
M
Ohashi
Shinji
S
Okamura
Shozo
S
Goto
Hidemi
H
D000328:Adult; D002404:Catheterization; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D005260:Female; D006801:Humans; D007417:Intestinal Polyps / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D007421:Intestine, Small; D008297:Male; D010580:Peutz-Jeghers Syndrome / Q000150:complications*