title: Longitudinal assessment of ovarian perifollicular and endometrial vascularity by power Doppler ultrasound in pregnant and non-pregnant cycles in the IVF setting.
abstract: OBJECTIVE
  This longitudinal study aimed to compare ovarian perifollicular and endometrial blood flow (PFBF and EBF, respectively) during the follicular phase in pregnant and non-pregnant IVF cycles.
  
  
  METHODS
  Serial transvaginal scans were performed in 15 subjects undergoing IVF treatment. Both PFBF and EBF were subjectively graded (grades 0-4 for PFBF and grades 1-3 for EBF). After confirmation of clinical pregnancy, the treatment cycles were grouped into 'Pregnant' and 'Non-pregnant' cycles. Ovarian PFBF and EBF were retrospectively compared between the two groups.
  
  
  RESULTS
  In pregnant cycles, the proportion of large (> or = 15 mm) follicles with high (24) grade PFBF increased with time throughout the follicular phase, and the proportion of large follicles with poor (0-1) grade PFBF decreased. In non-pregnant cycles these trends were reversed. There was no difference in EBF between the two groups.
  
  
  CONCLUSIONS
  The pattern of ovarian PFBF but not EBF may be predictive of treatment outcome.
authors.affiliation: School of Women's and Children's Health, University of New South Wales, Sydney, Australia.
authors.forename: S M
authors.initials: SM
authors.lastname: Shrestha
authors.forename: M F
authors.initials: MF
authors.lastname: Costello
authors.forename: P
authors.initials: P
authors.lastname: Sjoblom
authors.forename: G
authors.initials: G
authors.lastname: McNally
authors.forename: M J
authors.initials: MJ
authors.lastname: Bennett
authors.forename: S J
authors.initials: SJ
authors.lastname: Steigrad
authors.forename: G J
authors.initials: GJ
authors.lastname: Hughes
mesh_terms: D000328:Adult; D004717:Endometrium / Q000098:blood supply* / Q000000981:diagnostic imaging*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008137:Longitudinal Studies; D006080:Ovarian Follicle / Q000098:blood supply* / Q000000981:diagnostic imaging*; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D016896:Treatment Outcome; D018608:Ultrasonography, Doppler