title: Leptospirosis: a case report of a patient with pulmonary haemorrhage successfully managed with extra corporeal membrane oxygenation.
abstract: Leptospirosis is a zoonosis of worldwide significance. Pulmonary involvement is common but often mild and of little clinical significance. However, over the last two decades an increasing number of cases have been reported with pulmonary haemorrhage as a prominent feature [Carvalho CR, Bethlem EP. Pulmonary complications of leptospirosis. Clin Chest Med, 2002;23(2):469-78]. These cases are particularly challenging to treat as they often have resistant hypoxaemia despite maximal invasive mechanical ventilation. Consequently, there is a high mortality rate. Here, we present a case of severe leptospirosis complicated by massive pulmonary haemorrhage which was successfully managed by extra corporeal membrane oxygenation (ECMO).
authors.affiliation: Infectious Disease Department, Castle Hill Hospital, Hull, Cottingham, North Humberside HU16 5JQ, UK.
authors.forename: D
authors.initials: D
authors.lastname: Arokianathan
authors.forename: K
authors.initials: K
authors.lastname: Trower
authors.forename: S
authors.initials: S
authors.lastname: Pooboni
authors.forename: A
authors.initials: A
authors.lastname: Sosnowski
authors.forename: P
authors.initials: P
authors.lastname: Moss
authors.forename: H
authors.initials: H
authors.lastname: Thaker
mesh_terms: D000328:Adult; D015199:Extracorporeal Membrane Oxygenation; D006470:Hemorrhage / Q000209:etiology / Q000382:microbiology / Q000628:therapy*; D006801:Humans; D007919:Leptospira / Q000302:isolation & purification; D007922:Leptospirosis / Q000150:complications* / Q000382:microbiology; D008171:Lung Diseases / Q000209:etiology / Q000382:microbiology / Q000628:therapy*; D008297:Male