title: Analgesic and antipyretic activities of the aqueous extract of Urtica macrorrhiza in experimental animals.
abstract: Oral administration of the aqueous extract of the stem of Urtica macrorrhiza (100-400 mg/kg) dose dependently reduced the number of writhings and stretchings induced by acetic acid and decreased licking activity of the late phase in formalin test at doses of 200 and 400 mg/kg. At doses of 200 and 400 mg/kg, p.o. it suppressed yeast-induced fever in rats.
authors.affiliation: Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, Kunming Medical College, Kunming, Yunnan, 650031, PR China. mszhaoyn@yahoo.com.cn
authors.forename: Zhao
authors.initials: Z
authors.lastname: Yongna
authors.forename: Reanmongkol
authors.initials: R
authors.lastname: Wantana
authors.forename: Bouking
authors.initials: B
authors.lastname: Pisit
authors.forename: Li
authors.initials: L
authors.lastname: Zhongkun
authors.forename: Zhang
authors.initials: Z
authors.lastname: Rongping
mesh_terms: D019342:Acetic Acid; D000284:Administration, Oral; D000700:Analgesics / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005334:Fever / Q000517:prevention & control*; D005557:Formaldehyde; D008297:Male; D010146:Pain / Q000139:chemically induced / Q000517:prevention & control; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018547:Plant Stems; D051381:Rats; D027003:Urticaceae; D015003:Yeasts
chemical_list: D000700:Analgesics; D018712:Analgesics, Non-Narcotic; D010936:Plant Extracts; D005557:Formaldehyde; D019342:Acetic Acid