title: Sonographic markers of exencephaly below 10 weeks' gestation.
abstract: We report two cases of exencephaly diagnosed by transvaginal ultrasonography at 8 weeks 4 days and at 9 weeks 3 days of gestation. Both cases presented an irregular cephalic pole, and, in the case seen at 8 weeks 4 days, brain vesicles were also absent, whereas in the case seen at 9 weeks 3 days, the midline echo was indistinguishable with disorganized choroid plexuses. In both cases, anencephaly was evident at 11 and 12 weeks' gestation and the postmortem confirmed the diagnosis.
authors.affiliation: Fetal Medicine Unit, Department of Obstetrics, Hospital das Clínicas, São Paulo University Medical School, Brazil.
authors.forename: R A
authors.initials: RA
authors.lastname: Machado
authors.forename: M L
authors.initials: ML
authors.lastname: Brizot
authors.forename: M H B
authors.initials: MH
authors.lastname: Carvalho
authors.forename: A L
authors.initials: AL
authors.lastname: Waissman
authors.forename: V
authors.initials: V
authors.lastname: Bunduki
authors.forename: M
authors.initials: M
authors.lastname: Zugaib
mesh_terms: D000025:Abortion, Eugenic; D000328:Adult; D000757:Anencephaly / Q000000981:diagnostic imaging*; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D016216:Ultrasonography, Prenatal