title: Furocoumarin glycosides from the leaves of Ficus ruficaulis Merr. var. antaoensis.
abstract: From the methanolic extract of the leaves of Ficus ruficaulis Merr. var. antaoensis, 5-O-beta-D-glucopyranosyl-6-hydroxyangelicin (1), 6-O-beta-D-glucopyranosyl-5-hydroxyangelicin (2), 5,6-O-beta-D-diglucopyranosylangelicin (3), 8-O-beta-D-glucopyranosyl-5-hydroxypsoralen (4), 5-O-beta-D-glucopyranosyl-8-hydroxypsoralen (5), 3,4,5-trihydroxydehydro-alpha-ionol-9-O-beta-D-glucopyranoside (6), rutin (7), and isoquercitrin (8) were isolated. The structures of compounds 1-4 were elucidated by the analysis of their spectroscopic data. Their in vitro antiproliferation activities were also evaluated.
authors.affiliation: Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan 251, Republic of China.
authors.forename: Mau-Sun
authors.initials: MS
authors.lastname: Chang
authors.forename: Yuh-Cheng
authors.initials: YC
authors.lastname: Yang
authors.forename: Yuh-Chi
authors.initials: YC
authors.lastname: Kuo
authors.forename: Yueh-Hsiung
authors.initials: YH
authors.lastname: Kuo
authors.forename: Chen
authors.initials: C
authors.lastname: Chang
authors.forename: Chin-Mei
authors.initials: CM
authors.lastname: Chen
authors.forename: Tzong-Huei
authors.initials: TH
authors.lastname: Lee
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D030681:Ficus / Q000737:chemistry*; D011564:Furocoumarins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D020128:Inhibitory Concentration 50; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012431:Rutin / Q000737:chemistry; D013237:Stereoisomerism; D013624:Taiwan
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D011564:Furocoumarins; D006027:Glycosides; D012431:Rutin