title: Investigation of the morphology of cell clones, derived from the mammalian EBTr cell line and their susceptibility to vaccine avian poxvirus strains FK and Dessau.
abstract: The ability for replication of vaccine avian pox viral strains FK and Dessau in cell clones, derived from the EBTr cell line, derived from embryonic bovine trachea, was studied. The derived seven cell clones showed different morphological characteristics and diverse sensitivity to both vaccine avian pox viral strains. Hence, the EBTr-derived cell clones could be used for cultivation, as well as for differentiation of vaccine avian pox viral strains. In addition, studies have been undertaken to elucidate the possible use of cultivated strains in these heterologous cell culture system's vaccine avian pox viral strains for biotechnology, as well as for solving problems, related to infection of people with avian viruses.
authors.affiliation: Bulgarian Academy of Sciences, Central Laboratory of Optical Storage and Processing of Information, Acad. Georgi Bonchev Street, Block 101, P.O. Box 95, 1113 Sofia, Bulgaria. isainova@optics.bas.bg
authors.forename: Iskra Ventseslavova
authors.initials: IV
authors.lastname: Sainova
authors.forename: Anton Ivanov
authors.initials: AI
authors.lastname: Kril
authors.forename: Konstantin Borisov
authors.initials: KB
authors.lastname: Simeonov
authors.forename: Theodora Petrova
authors.initials: TP
authors.lastname: Popova
authors.forename: Ivan Georgiev
authors.initials: IG
authors.lastname: Ivanov
mesh_terms: D000818:Animals; D018150:Avipoxvirus / Q000502:physiology*; D002417:Cattle; D002460:Cell Line; D002999:Clone Cells; D014132:Trachea / Q000166:cytology* / Q000821:virology*; D014765:Viral Vaccines; D014779:Virus Replication
chemical_list: D014765:Viral Vaccines