title: Pulmonary atresia with intact ventricular septum and antenatal left ventricular failure.
abstract: Pulmonary atresia with intact ventricular septum has been described extensively, and it is recognized that associated abnormalities of the coronary arteries may cause ischemia. We describe a fetus, diagnosed antenatally as having pulmonary atresia with intact ventricular septum and severe hypoplasia of the right ventricle, who developed severe left ventricular dysfunction. We hypothesize that this is due to reduced coronary blood flow because of falling right ventricular volume in the presence of complete right ventricular coronary arterial dependence.
authors.affiliation: Department of Pediatrics, Division of Cardiology, British Columbia Children's Hospital, Vancouver, B.C., Canada.
authors.forename: Saad
authors.initials: S
authors.lastname: Khoshhal
authors.forename: George G S
authors.initials: GG
authors.lastname: Sandor
authors.forename: Walter J
authors.initials: WJ
authors.lastname: Duncan
mesh_terms: D004562:Electrocardiography; D006345:Heart Septal Defects, Ventricular / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D018633:Pulmonary Atresia / Q000150:complications* / Q000000981:diagnostic imaging; D016216:Ultrasonography, Prenatal; D018487:Ventricular Dysfunction, Left / Q000150:complications*