IgA nephropathy in association with Crohn's disease.
BACKGROUND
Urological complications of inflammatory bowel disease are seen in up to 25% of patients, but renal parenchymal disease is rarely reported.


METHODS
The authors describe a case of a 29-year-old man with clinical and radiological features of ileocaecal Crohn's disease. He had previously been investigated for painless macroscopic haematuria and a renal biopsy had revealed IgA nephropathy. Despite medical treatment, regular exacerbations of Crohn's disease were associated with deterioration in renal function and the development of haematuria. The patient eventually underwent surgical resection of the terminal ileum and caecum. His renal disease has remained quiescent for the last 5 years following resection.
Forshaw
M J
MJ
Department of Surgery, Princess Royal University Hospital, Farnborough Common, Orpington, Kent BR6 8ND, UK. mjforshaw@doctors.org.uk
Guirguis
O
O
Hennigan
T W
TW
D000328:Adult; D003082:Colectomy; D003424:Crohn Disease / Q000150:complications* / Q000473:pathology / Q000601:surgery; D005922:Glomerulonephritis, IGA / Q000209:etiology* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male