Indirect immunofluorescence--a method for diagnosis of autoimmune endocrine diseases, by putting in evidence serum auto-antibodies.
Used indirect immunofluorescence to put in evidence different types of auto-antibodies, involved in the etiopathogenesis of endocrine autoimmune diseases--thyroid auto-antibodies, anti-sperm antibodies, determined in the serum of both partners of the infertile couples, with infertility of unknown cause, ovary auto-antibodies, in early menopause cases. Besides the establish of a precise etiological diagnosis, this method offers the possibility to localize the auto-antibodies in the tissue and/or in the cells and also the chance to identify some types of auto-antibodies. In the case of thyroid auto-antibodies--antithyroglobulin and antimicrosomal antibodies, in the case of anti-sperm antibodies--anti-head, anti-intermediary piece, anti-acrosomal or anti-tail and anti-ovary antibodies--anti-oocyte, anti tecca granulosa or anti internal tecca.
Luca
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IC
Depart. of Histology, U.M.F. "Gr. T. Popa", Iasi.
D001323:Autoantibodies / Q000097:blood*; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000276:immunology; D004700:Endocrine System Diseases / Q000175:diagnosis* / Q000276:immunology; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006111:Graves Disease / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D007246:Infertility / Q000175:diagnosis / Q000276:immunology; D008297:Male; D008594:Menopause, Premature / Q000276:immunology; D010053:Ovary / Q000276:immunology; D013094:Spermatozoa / Q000276:immunology; D013961:Thyroid Gland / Q000276:immunology; D013967:Thyroiditis, Autoimmune / Q000175:diagnosis / Q000276:immunology
D001323:Autoantibodies