Effect of human serum on bioluminescence of natural and recombinant luminescent bacteria.
Biphasic modification of bacterial bioluminescence by human serum was revealed: bioluminescence was inhibited at high concentrations of the serum and stimulated at low concentrations. Effects of temperature and duration of exposure on bioluminescence manifested in stimulation of the inhibitory effect at higher temperature and longer exposure. The degree of inhibition of bioluminescence under in the presence of serum depends on species characteristics of the microorganism and nature of the luminescent system.
Deryabin
D G
DG
Orenburg State University. dgderyabin@yandex.ru
Polyakov
E G
EG
D003470:Culture Media / Q000494:pharmacology; D004926:Escherichia coli / Q000737:chemistry* / Q000235:genetics; D006801:Humans; D049449:Luminescence; D008163:Luminescent Measurements; D010776:Photobacterium / Q000737:chemistry* / Q000187:drug effects; D020637:Photorhabdus / Q000737:chemistry*; D044967:Serum
D003470:Culture Media