title: Calcium supplements to prevent colorectal adenomas.
abstract: Calcium supplements have been shown to decrease the risk of colorectal adenomas. In this issue of the Journal, Shaukat et al. report the results of a systematic review and meta-analysis of randomized controlled trials of calcium supplementation. The authors statistically combined the data from the three trials that met strict eligibility criteria. The overall relative risk was 0.80 (95% CI: 0.68-0.93) and the number needed to treat was 14. The results of this meta-analysis support a preventive role for calcium supplements.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Sandler
mesh_terms: D000236:Adenoma / Q000517:prevention & control*; D002118:Calcium / Q000008:administration & dosage*; D018890:Chemoprevention; D015179:Colorectal Neoplasms / Q000517:prevention & control*; D019587:Dietary Supplements; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control
chemical_list: D002118:Calcium