title: Safety and efficacy of drug-eluting stents.
abstract: This review characterizes the relative effectiveness and safety of drug-eluting stents (DES) compared to bare metal stents. The data evaluated will include clinical and angiographic outcomes from randomized clinical trials as well as observational databases and registries including RESEARCH, e-Cypher, and DYNAMIC, which typically include a much broader spectrum of patients. In addition, specific patient subsets, including those patients with multivessel coronary disease, will be evaluated.
authors.affiliation: Department of Cardiology, Rhode Island Hospital, Providence, Rhode Island, USA.
authors.forename: David O
authors.initials: DO
authors.lastname: Williams
authors.forename: Dean J
authors.initials: DJ
authors.lastname: Kereiakes
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D019917:Blood Vessel Prosthesis Implantation; D020099:Coated Materials, Biocompatible / Q000009:adverse effects / Q000627:therapeutic use*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000473:pathology / Q000628:therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D017239:Paclitaxel / Q000627:therapeutic use; D016032:Randomized Controlled Trials as Topic; D012042:Registries; D012449:Safety; D020123:Sirolimus / Q000627:therapeutic use; D015607:Stents / Q000009:adverse effects; D016896:Treatment Outcome
chemical_list: D020099:Coated Materials, Biocompatible; D007166:Immunosuppressive Agents; D017239:Paclitaxel; D020123:Sirolimus