title: Effects of microhydrin supplementation on endurance performance and metabolism in well-trained cyclists.
abstract: This study investigated whether the supplement Microhydrin (MH) contains silica hydride bonds (Si-H) and if Microhydrin supplementation increased performance or altered metabolism compared to placebo (PL) during prolonged endurance cycling. Seven endurance-trained male cyclists consumed 9.6 g of MH or PL over 48 h in a randomized, double-blind, crossover design. Subjects cycled at approximately 70% of their VO2peak, coupled with five 2-min bursts at 85% VO2peak to simulate hill climbs over 2 h. Subjects then completed a time trial, which required them to complete 7 kJ/kg body mass as quickly as possible. Infrared spectrometry analysis showed a complete absence of Si-H bonds in MH. There was no difference in time trial performance between the 2 trials (PL: 2257+/-120 s vs. MH: 2345+/-152 s). Measured oxygen uptake, respiratory exchange ratio, carbohydrate (MH: 2.99+/-0.13 g/min; PL: 2.83+/-0.17 g/min avg. over 2 h) and fat (MH: 0.341+/-0.06 g/min; PL: 0.361+/-0.07 g/min) oxidation rates and all blood parameters (lactate, glucose, and free fatty acids) were all unaffected by MH supplementation. The volume of expired CO2 and ventilation were significantly greater with MH supplementation (P < or = 0.05). The results indicate that oral Microhydrin supplementation does not enhance cycling time trial performance or alter metabolism during prolonged submaximal exercise in endurance-trained cyclists.
authors.affiliation: Dept of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G 2W1.
authors.forename: Lee R
authors.initials: LR
authors.lastname: Glazier
authors.forename: Trent
authors.initials: T
authors.lastname: Stellingwerff
authors.forename: Lawrence L
authors.initials: LL
authors.lastname: Spriet
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000494:pharmacology*; D001642:Bicycling / Q000502:physiology*; D002245:Carbon Dioxide / Q000378:metabolism; D018592:Cross-Over Studies; D019587:Dietary Supplements; D004311:Double-Blind Method; D004734:Energy Metabolism / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008297:Male; D010085:Oxidative Phosphorylation / Q000187:drug effects; D010101:Oxygen Consumption / Q000187:drug effects / Q000502:physiology; D010807:Physical Endurance / Q000187:drug effects* / Q000502:physiology; D017640:Silicates / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D017640:Silicates; C487012:silica hydride; D002245:Carbon Dioxide