title: [Influence of body constitution on bone mineral density measured by digital radiogrammetry].
abstract: OBJECTIVE
  In addition to many established osteodensitometric techniques, digital radiogrammetry (DXR) is considered to be a reliable method for measuring the cortical bone mineral density (DXR-BMD). This study investigates the influence of body constitution on BMD of healthy adults as calculated by DXR.
  
  
  METHODS
  In a prospective study, 246 adults without bone affecting diseases in their clinical history underwent DXR for analysis and calculations of bone mineral density and determination of metacarpal index (MCI) and porosity index (PI). Height, weight and body mass index (BMI) were recorded for each patient.
  
  
  RESULTS
  For all individuals and for all BMI subgroups, both height (0.55 < R < 0.70, p < 0.01) and body weight (0.56 < R < 0.78, p < 0.01) correlated closely with DXR-BMD. Only in the over-weight group, no significant correlation was found between body weight and DXR-BMD. In addition, a significant reduction of the relative DXR-BMD and MCI values was observed between the over-weight and the under-weight group as well as between normal-weight and under-weight individuals (p < 0.01). Otherwise, cortical porosity decreased with increasing body weight.
  
  
  CONCLUSIONS
  Similar to Dual Energy X-ray Absorptiometry-based studies (DXA), digital radiogrammetry measures an increase in BMD with increasing body weight. Therefore DXR, which provides a precise technique without influence of soft tissue, seems to be a promising technique for quantifying marginal alterations in cortical BMD as well for following the course of osteoporosis.
authors.affiliation: Institut für Diagnostische und Interventionelle Radiologie, Friedrich-Schiller-Universität Jena. joachim.boettcher@med.uni-jena.de
authors.forename: J
authors.initials: J
authors.lastname: Böttcher
authors.forename: A
authors.initials: A
authors.lastname: Pfeil
authors.forename: F
authors.initials: F
authors.lastname: Teufl
authors.forename: A
authors.initials: A
authors.lastname: Petrovitch
authors.forename: G
authors.initials: G
authors.lastname: Lehmann
authors.forename: A
authors.initials: A
authors.lastname: Kramer
authors.forename: H-J
authors.initials: HJ
authors.lastname: Mentzel
authors.forename: A
authors.initials: A
authors.lastname: Hansch
authors.forename: A
authors.initials: A
authors.lastname: Malich
authors.forename: G
authors.initials: G
authors.lastname: Hein
authors.forename: W A
authors.initials: WA
authors.lastname: Kaiser
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods*; D000328:Adult; D000886:Anthropometry; D015992:Body Mass Index; D015519:Bone Density; D005260:Female; D007839:Functional Laterality; D006225:Hand / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D011446:Prospective Studies; D011856:Radiographic Image Enhancement