Teaching resources. A model for fast-track exocytosis of synaptic vesicles.
The animation illustrates one model for "kiss-and-run" or fast-track release of neurotransmitter through a calcium-triggered transient pore formed between the synaptic vesicle and plasma membrane. The vesicles remain attached to the plasma membrane throughout the cycle. The animation illustrates a role for SNARE proteins and dynamin in the formation and closure of the pore. The animation would be useful in both neurobiology courses, but also any cell biology course that explores calcium-regulated secretion events.
Galli
Thierry
T
Membrane Traffic and Neuronal Plasticity Group, INSERM U536, Institut du Fer-à-moulin, 75005 Paris, France. thierry@tgalli.net <thierry@tgalli.net>
Haucke
Volker
V
D001296:Audiovisual Aids; D001671:Biochemistry / Q000193:education; D002118:Calcium / Q000502:physiology; D003585:Cell Biology / Q000193:education; D005089:Exocytosis; D008954:Models, Biological; D009446:Neurobiology / Q000193:education; D050600:SNARE Proteins / Q000502:physiology; D013572:Synaptic Vesicles / Q000502:physiology
D050600:SNARE Proteins; D002118:Calcium