title: A thoracic-epidural granulocytic sarcoma case that was diagnosed preceding the onset of and that recurred co-incidental to acute promyelocytic leukemia, which developed after surgical treatment.
abstract: Granulocytic sarcoma or chloroma is a tumor seen in myelocytic leukemia. Spinal epidural onset is rare and is generally seen before or together with the onset of myelocytic leukemia. An epidural mass located at the 2nd-5th thoracic levels in an 18-year-old male patient was pathologically diagnosed as granulocytic sarcoma. Radiotherapy was performed after surgical intervention. Ten months later, he was re-admitted with abdominal pain. At this time, an epidural mass at the 6th-9th thoracic levels was detected on magnetic resonance imaging, and acute promyelocytic leukemia was diagnosed. After systemic chemotherapy, partial remission was achieved. We aimed to present this rare case with its remarkable follow-up findings.
authors.affiliation: Department of Radiology, Zonguldak Karaelmas University, Faculty of Medicine, Zonguldak, Turkey. savranlar@yahoo.com
authors.forename: Ahmet
authors.initials: A
authors.lastname: Savranlar
authors.forename: Yücel
authors.initials: Y
authors.lastname: Ustündag
authors.forename: Tülay
authors.initials: T
authors.lastname: Ozer
authors.forename: Taner
authors.initials: T
authors.lastname: Bayraktaroglu
authors.forename: Nejat
authors.initials: N
authors.lastname: Demircan
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Ozdemir
authors.forename: Ali
authors.initials: A
authors.lastname: Borazan
mesh_terms: D000293:Adolescent; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003561:Cytarabine / Q000008:administration & dosage; D003630:Daunorubicin / Q000008:administration & dosage; D004824:Epidural Space; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D009364:Neoplasm Recurrence, Local; D016609:Neoplasms, Second Primary; D023981:Sarcoma, Myeloid / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D013125:Spinal Neoplasms / Q000175:diagnosis*; D013904:Thoracic Vertebrae
chemical_list: D000903:Antibiotics, Antineoplastic; D000964:Antimetabolites, Antineoplastic; D003561:Cytarabine; D003630:Daunorubicin