title: Median raphe cyst in the scrotum, mimicking a serous borderline tumor, associated with cryptorchidism after orchiopecxy.
abstract: Median raphe cyst (MRC) is a benign lesion occurring predominantly in the ventral surface of the penises of young men and is an embryological developmental anomaly of the male genitalia. Serous borderline tumors (SBT) are found most frequently in the female ovary and only several cases with SBT of the male genitalia have been reported. We describe a case of MRC with features of SBT, which appeared in the scrotum of a 9-year-old boy after orchiopexy and was associated with surgery for cryptorchidism. The cyst arose on the right testicular tunica and consisted of cystic components with intracystic papillae lined by stratified epithelial cells, some of which showed mild cytological atypia and sporadic mitosis. These epithelial cells expressed CA 125, CA 19-9, carcinoembryonic antigen, estrogen receptor and progesterone receptor. Although no cases of MRC with characteristics of SBT in association with the rete testis has been described, the current report gives additional information for follow-up of cryptorchidism.
authors.affiliation: Division of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachi 1, Niigata 951, Japan. harasho@med.niigata-u.ac.jp
authors.forename: Noboru
authors.initials: N
authors.lastname: Hara
authors.forename: Makoto
authors.initials: M
authors.lastname: Kawaguchi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Koike
authors.forename: Kota
authors.initials: K
authors.lastname: Takahashi
mesh_terms: D002648:Child; D003456:Cryptorchidism / Q000150:complications* / Q000276:immunology / Q000601:surgery; D018293:Cystadenoma, Serous / Q000473:pathology*; D003937:Diagnosis, Differential; D004814:Epidermal Cyst / Q000209:etiology / Q000276:immunology / Q000473:pathology*; D006801:Humans; D008297:Male; D009919:Orchiectomy; D012611:Scrotum / Q000276:immunology / Q000473:pathology*