title: Association between mild vascular cognitive impairment and impaired activities of daily living in older stroke survivors without dementia.
abstract: OBJECTIVE
  To determine the relationship between mild vascular cognitive impairment (mVCI) and functional disability in older stroke survivors without dementia.
  
  
  METHODS
  Cohort study.
  
  
  METHODS
  Stroke patients from representative hospital-based stroke registers.
  
  
  METHODS
  Three hundred thirty-nine stroke survivors without dementia, aged 75 and older.
  
  
  METHODS
  Neuropsychological assessments were completed 3 months poststroke. Activities of daily living (ADLs) were evaluated using the Bristol scale. Operationalized criteria, including cognitive impairment no dementia (CIND), were applied for mVCI.
  
  
  RESULTS
  Significant impairments of ADLs were evident in mVCI (CIND vs no CIND; basic care: z=3.2; P=.001, intermediate care: z=3.6; P<.001, complex management: z=4.5; P<.001) but varied according to the profile of cognitive impairments. Patients with attentional or global impairments had more severe functional disability than patients with isolated memory deficits, with an intermediate level of dysfunction in patients with executive impairments.
  
  
  CONCLUSIONS
  The findings emphasize the importance of identifying early cognitive impairments to optimize rehabilitation, care planning, and secondary prevention of dementia in stroke patients.
authors.affiliation: University of Newcastle, UK.
authors.forename: Sally
authors.initials: S
authors.lastname: Stephens
authors.forename: Rose Anne
authors.initials: RA
authors.lastname: Kenny
authors.forename: Elise
authors.initials: E
authors.lastname: Rowan
authors.forename: Raj N
authors.initials: RN
authors.lastname: Kalaria
authors.forename: Michael
authors.initials: M
authors.lastname: Bradbury
authors.forename: Ruth
authors.initials: R
authors.lastname: Pearce
authors.forename: Keith
authors.initials: K
authors.lastname: Wesnes
authors.forename: Clive G
authors.initials: CG
authors.lastname: Ballard
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000098:blood supply; D003072:Cognition Disorders / Q000150:complications* / Q000209:etiology*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D020521:Stroke / Q000150:complications*; D000071939:Stroke Rehabilitation; D017741:Survivors