title: [Evaluation of anti-HCV detection kits using recombinant antigens derived from various HCV regions].
abstract: OBJECTIVE
  To evaluate the first and second assay kits currently used in blood centers for screening HCV infected blood, and to provide basis for a better match of the two assay kits.
  
  
  METHODS
  Using the newly developed multi-recombinant-HCV-antigen supplementary assay kit, the authors evaluated concurrently the specificity and sensitivity of two domestic and one imported anti-HCV detection kits.
  
  
  RESULTS
  Discrepancy in specificity and sensitivity existed among the two domestic HCV kits, and overall quality was slightly below that of leading or main stream imported HCV kit.
  
  
  CONCLUSIONS
  The newly developed multi-recombinant-HCV-antigen supplementary assay kit is useful in the evaluation of HCV antibody detection kit currently in use. It provides qualified assessing kit to capture antibodies against various HCV antigens. The present paper provided guidance for selecting a better match of the two screening kits and improved screening efficiency.
authors.affiliation: Changchun Municipal Blood Center, Changchun 130031, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Deng
authors.forename: Hui-jie
authors.initials: HJ
authors.lastname: Zhang
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Qiu-ping
authors.initials: QP
authors.lastname: Wang
authors.forename: Ji-hui
authors.initials: JH
authors.lastname: Chu
authors.forename: He-qui
authors.initials: HQ
authors.lastname: Zhang
mesh_terms: D001782:Blood Donors; D005069:Evaluation Studies as Topic; D016174:Hepacivirus / Q000235:genetics / Q000276:immunology*; D018937:Hepatitis C Antibodies / Q000097:blood* / Q000276:immunology; D018936:Hepatitis C Antigens / Q000235:genetics / Q000276:immunology*; D006801:Humans; D011933:Reagent Kits, Diagnostic / Q000592:standards*; D012680:Sensitivity and Specificity
chemical_list: D018937:Hepatitis C Antibodies; D018936:Hepatitis C Antigens; D011933:Reagent Kits, Diagnostic