title: We think we see a pattern emerging here.
authors.forename: James M
authors.initials: JM
authors.lastname: Downey
authors.forename: Michael V
authors.initials: MV
authors.lastname: Cohen
mesh_terms: D000818:Animals; D015415:Biomarkers; D002118:Calcium / Q000378:metabolism; D002316:Cardiotonic Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D002470:Cell Survival / Q000187:drug effects; D003327:Coronary Disease / Q000503:physiopathology; D004285:Dogs; D015195:Drug Design; D004789:Enzyme Activation / Q000187:drug effects; D048049:Extracellular Signal-Regulated MAP Kinases / Q000502:physiology*; D005542:Forearm / Q000098:blood supply; D006801:Humans; D007473:Ion Channels / Q000187:drug effects / Q000502:physiology*; D017136:Ion Transport / Q000187:drug effects; D007511:Ischemia / Q000188:drug therapy / Q000503:physiopathology; D019157:Ischemic Preconditioning, Myocardial; D020935:MAP Kinase Signaling System / Q000187:drug effects / Q000502:physiology*; D008929:Mitochondria, Heart / Q000187:drug effects / Q000502:physiology*; D033681:Mitochondrial Membrane Transport Proteins; D000083162:Mitochondrial Permeability Transition Pore; D009203:Myocardial Infarction / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D032383:Myocytes, Cardiac / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D017346:Protein Serine-Threonine Kinases / Q000502:physiology*; D011518:Proto-Oncogene Proteins / Q000502:physiology*; D051057:Proto-Oncogene Proteins c-akt; D011817:Rabbits; D051381:Rats; D013045:Species Specificity
chemical_list: D015415:Biomarkers; D002316:Cardiotonic Agents; D007473:Ion Channels; D033681:Mitochondrial Membrane Transport Proteins; D000083162:Mitochondrial Permeability Transition Pore; D011518:Proto-Oncogene Proteins; D017346:Protein Serine-Threonine Kinases; D051057:Proto-Oncogene Proteins c-akt; D048049:Extracellular Signal-Regulated MAP Kinases; D002118:Calcium