MAPKAP kinase-2: three's company at the G(2) checkpoint.
Elegant studies in fission yeast by and in mammalian cells by offer new insights into the mechanism through which stress-induced p38 activation inhibits mitotic entry in eukaryotic cells.
Abraham
Robert T
RT
Signal Transduction Program, The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
D018797:Cell Cycle Proteins / Q000378:metabolism; D004789:Enzyme Activation; D016195:G2 Phase / Q000502:physiology*; D018816:Genes, cdc; D047908:Intracellular Signaling Peptides and Proteins; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D012568:Schizosaccharomyces / Q000166:cytology / Q000378:metabolism / Q000528:radiation effects; D014466:Ultraviolet Rays; D048051:p38 Mitogen-Activated Protein Kinases / Q000378:metabolism; D000099190:MAP-Kinase-Activated Kinase 2
D018797:Cell Cycle Proteins; D047908:Intracellular Signaling Peptides and Proteins; D017346:Protein Serine-Threonine Kinases; D048051:p38 Mitogen-Activated Protein Kinases; D000099190:MAP-Kinase-Activated Kinase 2