Multiple avascular necrosis in a patient with systemic lupus erythematosus/systemic sclerosis overlap syndrome.
A white female patient developed overlapping features of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) with severe pulmonary compromise. She was treated with steroids and azathioprine, which improved her clinical condition and spirometric status. In May 2002 she presented with continuous pain in her left ankle that continued even during rest and under treatment with nonsteroidal anti-inflammatory drugs (NSAIDs). Magnetic resonance imaging (MRI) showed multiple avascular necrosis (AVN). Rest and kinesitherapy were indicated for 1 year, and gradually an orthosis was introduced allowing the patient to walk normally.
Cavallasca
Javier Alberto
JA
Division of Rheumatology, Hospital de Clinicas José de San Martín, Faculty of Medicine, University of Buenos Aires, Argentina. pravier@hotmail.com
Laborde
Hugo Armando
HA
Araujo
Mariela Beatriz
MB
Nasswetter
Gustavo Guillermo
GG
D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods; D020678:Microscopic Angioscopy; D009989:Orthotic Devices; D010020:Osteonecrosis / Q000150:complications / Q000175:diagnosis* / Q000534:rehabilitation; D010147:Pain Measurement; D018570:Risk Assessment; D012595:Scleroderma, Systemic / Q000150:complications / Q000175:diagnosis*; D012720:Severity of Illness Index; D013577:Syndrome; D014057:Tomography, X-Ray Computed