Changes in induced sputum in the presence of bronchiolitis obliterans syndrome and correlation with spirometry in single and bilateral lung transplant recipients.
Bronchiolitis obliterans syndrome is a clinical diagnosis based on lung function parameters. Using induced sputum, taken from lung transplant recipients, this paper reports on the correlation between the neutrophil count and the percentage change from postoperative baseline for FEV(1), FEF(50), and FEF(25-75). In double lung transplant recipients the correlations were significant for FEV(1) (r = -0.68, p = 0.002), FEF(50) (r = -0.65, p = 0.016), and FEF(25-75) (r = -0.56, p = 0.016). In single lung transplant recipients, no significant correlations were seen.
Allen
David J
DJ
North West Lung Research Centre, Wythenshawe Hospital, Southmoor Road, Wythenshawe, Manchester, UK M23 9LT.
Fildes
James E
JE
Yonan
Nizar
N
Leonard
Colm T
CT
D001989:Bronchiolitis Obliterans / Q000378:metabolism* / Q000503:physiopathology / Q000601:surgery*; D005540:Forced Expiratory Flow Rates / Q000502:physiology; D005541:Forced Expiratory Volume / Q000502:physiology; D006801:Humans; D007958:Leukocyte Count; D016040:Lung Transplantation; D009504:Neutrophils / Q000378:metabolism; D011183:Postoperative Complications / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology; D012129:Respiratory Function Tests; D012720:Severity of Illness Index; D013147:Spirometry; D013183:Sputum / Q000737:chemistry* / Q000378:metabolism; D013577:Syndrome; D016896:Treatment Outcome; D014797:Vital Capacity / Q000502:physiology