Highly efficient biosynthesis of the oligosaccharide moiety of the GD3 ganglioside by using metabolically engineered Escherichia coli.
Antoine
Tatiana
T
CERMAV-CNRS, B.P. 53, 38041 Grenoble Cedex 9, France.
Heyraud
Alain
A
Bosso
Claude
C
Samain
Eric
E
D016123:Campylobacter jejuni / Q000201:enzymology / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism*; D005732:Gangliosides / Q000096:biosynthesis* / Q000737:chemistry; D020868:Gene Silencing; D005818:Genetic Engineering / Q000379:methods*; D007785:Lactose / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D019158:N-Acetylneuraminic Acid / Q000378:metabolism; D000216:N-Acylneuraminate Cytidylyltransferase / Q000235:genetics / Q000378:metabolism; D009345:Neisseria meningitidis / Q000201:enzymology / Q000235:genetics; D009844:Oligosaccharides / Q000096:biosynthesis* / Q000737:chemistry; D007652:Oxo-Acid-Lyases / Q000235:genetics / Q000378:metabolism; D012799:Sialyltransferases / Q000235:genetics / Q000378:metabolism; D014169:Transformation, Bacterial; D001616:beta-Galactosidase / Q000235:genetics / Q000378:metabolism
D005732:Gangliosides; D009844:Oligosaccharides; C026226:ganglioside, GD3; D012799:Sialyltransferases; D000216:N-Acylneuraminate Cytidylyltransferase; D001616:beta-Galactosidase; D007652:Oxo-Acid-Lyases; C018728:N-acetylneuraminate lyase; D019158:N-Acetylneuraminic Acid; D007785:Lactose