title: Reactivity of Mitsunobu reagent toward carbonyl compounds.
abstract: [reaction: see text] The nitrogen-based nucleophile generated from azodicarboxylate and triphenylphosphine displayed an excellent reactivity toward carbonyl compounds to generate a variety of different final products depending on the substituent pattern on the carbonyl carbon. From the structures of these adducts, a straightforward mechanistic interpretation for the formation of different products is provided.
authors.affiliation: Department of Chemistry, University of Wisconsin, Madison, WI 53706, USA.
authors.forename: Ryan D
authors.initials: RD
authors.lastname: Otte
authors.forename: Tomoyo
authors.initials: T
authors.lastname: Sakata
authors.forename: Ilia A
authors.initials: IA
authors.lastname: Guzei
authors.forename: Daesung
authors.initials: D
authors.lastname: Lee
mesh_terms: D000438:Alcohols / Q000737:chemistry; D007202:Indicators and Reagents; D007659:Ketones / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation
chemical_list: D000438:Alcohols; D007202:Indicators and Reagents; D007659:Ketones