Cytokines and endometriosis.
BACKGROUND
Abnormal expression of cytokines is considered to be involved in the pathogenesis of endometriosis.


METHODS
In 63 women with various stages of endometriosis preoperative levels of cytokines, including IL-6, IL-8, BVEGF, b-FGF, of TNF RI and TNF RII were analysed employing ELISA tests (R&D kits).


RESULTS
In the sera of endometriosis patients significantly augmented levels of IL-6 and of b-FGF were detected as well as a trend for elevated IL-8 levels.


CONCLUSIONS
Elevated serum levels of cytokines may show poor correspondence to the localized pathological process. Endometriosis would find a stricter reflection in cytokine levels in fluids or tissues of the pelvis minor.
Markowska
J
J
Karol Marcinkowski University School of Medicine, Poznan, Poland.
Kowalska
M
M
Gogacz
M
M
Lubin
J
J
Markowski
M
M
Kamińska
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D016207:Cytokines / Q000097:blood*; D004715:Endometriosis / Q000378:metabolism* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged
D016207:Cytokines