Gastrointestinal bleeding from arteriovenous malformations in patients supported by the Jarvik 2000 axial-flow left ventricular assist device.
The long-term effects of axial-flow mechanical circulatory support in humans are unclear. We report 3 cases of chronic gastrointestinal bleeding after implantation of a Jarvik 2000 axial-flow left ventricular assist device. The bleeding was refractory to aggressive management and in 2 cases resolved only after orthotopic cardiac transplantation.
Letsou
George V
GV
Department of Cardiothoracic and Vascular Surgery, The University of Texas-Houston Medical School, 6410 Fannin, Suite #450, Houston, TX 77030, USA. george.v.letsou@uth.tmc.edu
Shah
Nyma
N
Gregoric
Igor D
ID
Myers
Timothy J
TJ
Delgado
Reynolds
R
Frazier
O H
OH
D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D001165:Arteriovenous Malformations / Q000150:complications*; D009202:Cardiomyopathies / Q000601:surgery; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D007421:Intestine, Small / Q000098:blood supply* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000601:surgery; D014859:Warfarin / Q000627:therapeutic use
D000925:Anticoagulants; D014859:Warfarin