title: FibreHelix, a program for calculating the X-ray diffraction pattern of macromolecules with helical symmetry: application to DNA coiled coils.
abstract: A program has been developed to determine the diffraction pattern given by partially ordered fibres formed by macromolecules with helical symmetry. It is particularly useful for visualizing the splitting of layer lines typical of coiled coils. The program produces as output the diffraction diagram calculated for helices that are oriented along their axis but are randomly oriented in other directions. The results can be numerically analyzed and also visualized on-screen. The program has been applied to the diffraction patterns given by DNA and protein coiled coils.
authors.affiliation: Algorithmics and Genetics Group, Software Department, Universitat Politècnica de Catalunya, C/Jordi Girona C6, 08034 Barcelona, Spain.
authors.forename: David
authors.initials: D
authors.lastname: Dominguez-Sal
authors.forename: Xavier
authors.initials: X
authors.lastname: Messeguer
authors.forename: Juan A
authors.initials: JA
authors.lastname: Subirana
mesh_terms: D018360:Crystallography, X-Ray; D004247:DNA / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D012984:Software
chemical_list: D004247:DNA