Best evidence topic report. Proteolytic enzymes for oesophageal meat impaction.
A short cut review was carried out to establish whether proteolytic enzymes are effective at resolving oesophageal meat impaction. Altogether 98 papers were found using the reported search, of which three presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these best papers are tabulated. A clinical bottom line is stated.
Lee
Jason
J
Department of Emergency Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.
Anderson
Ross
R
D031230:Ananas; D000818:Animals; D002417:Cattle; D004630:Emergencies; D004947:Esophagus; D019317:Evidence-Based Medicine; D005547:Foreign Bodies / Q000188:drug therapy*; D006801:Humans; D008460:Meat; D010206:Papain / Q000627:therapeutic use; D010447:Peptide Hydrolases / Q000009:adverse effects / Q000627:therapeutic use*
D010447:Peptide Hydrolases; D010206:Papain