title: Identification of white spot syndrome virus (WSSV) envelope proteins involved in shrimp infection.
abstract: White spot syndrome virus (WSSV) is a major shrimp pathogen causing large economic losses. In an attempt to identify the envelope proteins involved in virus infection, antisera against six WSSV envelope proteins were used in neutralization assays conducted in vivo. The results showed that the virus infection could be significantly delayed or neutralized by antibodies against three WSSV envelope proteins (VP68, VP281 and VP466). This neutralization was further confirmed by quantitative PCR. It could be concluded that the viral envelope proteins VP68, VP281 and VP466 played roles in WSSV infection to shrimp.
authors.affiliation: School of Life Sciences, Xiamen University, Xiamen 361005, The People's Republic of China.
authors.forename: Wenlin
authors.initials: W
authors.lastname: Wu
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Xiaobo
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001483:Base Sequence; D017931:DNA Primers; D033561:Penaeidae / Q000254:growth & development / Q000821:virology*; D016133:Polymerase Chain Reaction; D014759:Viral Envelope Proteins / Q000032:analysis*; D014771:Virion / Q000502:physiology; D046848:White spot syndrome virus 1 / Q000254:growth & development / Q000502:physiology*
chemical_list: D017931:DNA Primers; D014759:Viral Envelope Proteins