title: Two cases of hyperkalemia after administration of hypertonic mannitol during craniotomy.
abstract: Mannitol is used commonly as an osmotic diuretic to reduce intracranial pressure during the perioperative period of craniotomy. The rapid administration of mannitol solution can cause an imbalance of electrolytes such as sodium and potassium. Here, we report two cases of mannitol-induced hyperkalemia. We demonstrate that administration of mannitol during craniotomy increases potassium iron concentration, and in some cases it may cause disturbance of cardiac function.
authors.affiliation: Department of Anesthesia, The Tazuke Kofukai Medical Research Institute Kitano Hospital, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.
authors.forename: Kiichi
authors.initials: K
authors.lastname: Hirota
authors.forename: Tomoko
authors.initials: T
authors.lastname: Hara
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hosoi
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Sasaki
authors.forename: Yasufumi
authors.initials: Y
authors.lastname: Hara
authors.forename: Takehiko
authors.initials: T
authors.lastname: Adachi
mesh_terms: D000328:Adult; D000368:Aged; D000758:Anesthesia; D001784:Blood Gas Analysis; D020202:Cerebral Hemorrhage, Traumatic / Q000601:surgery; D003399:Craniotomy; D004232:Diuretics / Q000009:adverse effects*; D004562:Electrocardiography; D006801:Humans; D006947:Hyperkalemia / Q000097:blood / Q000139:chemically induced*; D006982:Hypertonic Solutions; D002532:Intracranial Aneurysm / Q000601:surgery; D007431:Intraoperative Complications / Q000097:blood / Q000139:chemically induced*; D007501:Iron / Q000097:blood; D008297:Male; D008353:Mannitol / Q000009:adverse effects*; D011188:Potassium / Q000097:blood; D013345:Subarachnoid Hemorrhage / Q000601:surgery; D014883:Water-Electrolyte Imbalance / Q000139:chemically induced
chemical_list: D004232:Diuretics; D006982:Hypertonic Solutions; D008353:Mannitol; D007501:Iron; D011188:Potassium