title: Comparative effects of non-gelatinized corn and rice starches on the life-span of ICR mice.
abstract: We compared the effects of non-gelatinized rice and corn starches on the life-span of ICR mice. Six groups of male ICR mice consisting of 30 animals each were maintained on purified experimental diets containing either corn or rice starch and different amounts of soybean oil (6, 12 or 24%) throughout their life-time. Plots of the survival rates of the mice indicate that rice compared to corn starch conferred a longer life-span to ICR mice, although a significant difference due to the starch type was only observed in the mice fed on the 24% fat diet (p=0.012). A divergent effect of rice and corn starches on the survival rate was apparent when observations were combined with respect to the starch type regardless of the dietary fat level (p=0.005). In addition, two-way ANOVA data indicate that the mean survival time was longer for the mice given rice starch (593-645 days) than for those fed corn starch (538-580 days) (p=0.011). However, no significant difference in these parameters due to dietary fat levels was observed. The results of our study indicate that starch type is one of the determinants of longevity in mice.
authors.affiliation: National Agricultural Research Center for Tohoku Region, National Agricultural Research Organization, Fukushima, Japan.
authors.forename: Kohji
authors.initials: K
authors.lastname: Yamaki
authors.forename: Takashi
authors.initials: T
authors.lastname: Ide
authors.forename: Yuko
authors.initials: Y
authors.lastname: Takano-Ishikawa
authors.forename: Kazuki
authors.initials: K
authors.lastname: Shinohara
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004040:Dietary Carbohydrates / Q000494:pharmacology*; D004041:Dietary Fats / Q000494:pharmacology; D008136:Longevity / Q000187:drug effects*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D012275:Oryza / Q000737:chemistry*; D013213:Starch / Q000737:chemistry / Q000494:pharmacology*; D003313:Zea mays / Q000737:chemistry*
chemical_list: D004040:Dietary Carbohydrates; D004041:Dietary Fats; D013213:Starch