title: The minimal interspecific introgression resulting in male sterility in Drosophila.
abstract: Introgression of Drosophila simulans genes into the Drosophila melanogaster genome provides an ideal system for analysing genetic incompatibility between species. Females and males homozygous for the introgression Int(2L)S (cytologically, 30F3-31C5 to 36A2-7) are sterile. Genetic dissection of the proximal part of the introgression (34D1-3 to 36A2-7) has indicated that introgressions of 0.7-1.6 Mb size result in male sterility when homozygous. In the present analysis we examine the distal part of the introgression (30F3-31C to 34D1-3) and reveal that introgressions with similar DNA content (1.8-2.1 Mb) result in male sterility. Compared with introgressions between the more closely related species Drosophila mauritiana and D. simulans, the minimal introgression resulting in male sterility is smaller by several-fold.
authors.affiliation: Drosophila Genetic Resource Center, Kyoto Institute of Technology, Ukyo-ku, Kyoto 616-8354, Japan. sawamura@biol.tsukuba.ac.jp
authors.forename: Kyoichi
authors.initials: K
authors.lastname: Sawamura
authors.forename: Masa-Toshi
authors.initials: MT
authors.lastname: Yamamoto
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D004330:Drosophila / Q000235:genetics* / Q000378:metabolism; D005260:Female; D006720:Homozygote; D006824:Hybridization, Genetic / Q000502:physiology*; D007248:Infertility, Male / Q000235:genetics* / Q000378:metabolism; D008297:Male; D017422:Sequence Analysis, DNA