The association between acute fatty liver of pregnancy and fatty acid oxidation disorders.
Acute fatty liver of pregnancy is a relatively rare but potentially fatal liver disorder of late pregnancy. Recent advances in molecular diagnostic procedures provide evidence of a genetic basis for this condition and a link to offspring disorders in fatty acid oxidation. This relationship implies the need for genetic testing and follow-up of at-risk women and their neonates.
Jamerson
Patricia A
PA
St. Louis Children's Hospital, 1 Children's Place, St. Louis, MO 63110, USA. paj3987@bjc.org
D000208:Acute Disease; D000328:Adult; D015897:Comorbidity; D005227:Fatty Acids / Q000378:metabolism*; D005234:Fatty Liver / Q000175:diagnosis* / Q000453:epidemiology* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008052:Lipid Metabolism, Inborn Errors / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D008431:Maternal-Fetal Exchange; D010084:Oxidation-Reduction; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000453:epidemiology; D011256:Pregnancy Outcome; D018570:Risk Assessment
D005227:Fatty Acids