The biosynthesis of vancomycin-type glycopeptide antibiotics--a model for oxidative side-chain cross-linking by oxygenases coupled to the action of peptide synthetases.
Bischoff
Daniel
D
Institut für Organische Chemie der Universität Tübingen, Auf der Morgenstelle 18, 72076 Tübingen, Germany.
Bister
Bojan
B
Bertazzo
Marcelo
M
Pfeifer
Volker
V
Stegmann
Efthimia
E
Nicholson
Graeme J
GJ
Keller
Simone
S
Pelzer
Stefan
S
Wohlleben
Wolfgang
W
Süssmuth
Roderich D
RD
D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000737:chemistry* / Q000627:therapeutic use; D005798:Genes, Bacterial; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010105:Oxygenases / Q000378:metabolism*; D010453:Peptide Synthases / Q000378:metabolism*; D013203:Staphylococcal Infections / Q000188:drug therapy; D014640:Vancomycin / Q000031:analogs & derivatives* / Q000096:biosynthesis* / Q000737:chemistry / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D014640:Vancomycin; D010105:Oxygenases; D010453:Peptide Synthases