title: Dramatic development of severe SLE in a patient with an incomplete disease.
abstract: This case report describes the previously-unreported clinical course of a patient with a so-called incomplete systemic lupus erythematosus (SLE), i.e. symptoms related to one organ system only, together with the presence of ANA. He had an indolent course initially and developed, 6 months after the first symptoms, a severe disease with rapid appearance of major and unusual manifestations. The possibility of fast progression and a grave course of an incomplete SLE should be kept in mind. This report is meant to heighten awareness of such an atypical presentation so that prompt and aggressive immunosuppressive therapy may be instituted.
authors.affiliation: Dipartimento di Medicina Interna, Università degli Studi Milano and IRCCS Ospedale Maggiore Policlinico, Pad. Granelli Via F. Sforza 35, 20122, Milan, Italy. giovanna.fabio@unimi.it
authors.forename: G
authors.initials: G
authors.lastname: Fabio
authors.forename: M
authors.initials: M
authors.lastname: Carrabba
authors.forename: C
authors.initials: C
authors.lastname: Hu
authors.forename: M
authors.initials: M
authors.lastname: Floriani
authors.forename: C
authors.initials: C
authors.lastname: Besana
mesh_terms: D000006:Abdomen, Acute / Q000175:diagnosis / Q000209:etiology; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D017152:Antibodies, Antiphospholipid / Q000276:immunology*; D000925:Anticoagulants / Q000627:therapeutic use; D003131:Combined Modality Therapy; D016638:Critical Illness; D018450:Disease Progression; D005500:Follow-Up Studies; D006801:Humans; D007415:Intestinal Obstruction / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D007813:Laparotomy / Q000379:methods; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D018570:Risk Assessment
chemical_list: D000305:Adrenal Cortex Hormones; D017152:Antibodies, Antiphospholipid; D000925:Anticoagulants