title: Serum oxidant/antioxidant balance in exfoliation syndrome.
abstract: BACKGROUND
  To evaluate the relationship between the serum oxidant-antioxidant balance and the presence of exfoliation syndrome (XFS) in a prospective study.
  
  
  METHODS
  The study group comprised 27 cases of XFS. Serum concentrations of myeloperoxidase, malondialdehyde, vitamins A, C and E, catalase and total antioxidant were measured and compared with an independent group by t-test.
  
  
  RESULTS
  Serum myeloperoxidase, vitamins A and E, catalase and total antioxidant parameters were not statistically different among the groups (P >0.05). Serum vitamin C concentrations were significantly lower and malondialdehyde concentrations were significantly higher in cases of XFS when compared with the control group (P=0.008 and P=0.002, respectively).
  
  
  CONCLUSIONS
  An altered oxidant-antioxidant balance may play a role in the pathogenesis of XFS.
authors.affiliation: Department of Ophthalmology, Mersin University Faculty of Medicine, Mersin, Turkey.
authors.forename: Ayça
authors.initials: A
authors.lastname: Yimaz
authors.forename: Ufuk
authors.initials: U
authors.lastname: Adigüzel
authors.forename: Lülüfer
authors.initials: L
authors.lastname: Tamer
authors.forename: Ozlem
authors.initials: O
authors.lastname: Yildirim
authors.forename: Ozay
authors.initials: O
authors.lastname: Oz
authors.forename: Halil
authors.initials: H
authors.lastname: Vatansever
authors.forename: Bahadir
authors.initials: B
authors.lastname: Ercan
authors.forename: Ula S
authors.initials: US
authors.lastname: Değirmenci
authors.forename: Uğur
authors.initials: U
authors.lastname: Atik
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000975:Antioxidants / Q000378:metabolism; D001205:Ascorbic Acid / Q000097:blood*; D002374:Catalase / Q000097:blood*; D017889:Exfoliation Syndrome / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D010084:Oxidation-Reduction; D009195:Peroxidase / Q000097:blood*; D011446:Prospective Studies; D014801:Vitamin A / Q000097:blood*; D014810:Vitamin E / Q000097:blood*
chemical_list: D000975:Antioxidants; D014801:Vitamin A; D014810:Vitamin E; D008315:Malondialdehyde; D002374:Catalase; D009195:Peroxidase; D001205:Ascorbic Acid