title: Prediction of growth and biotransformation rates of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) in the presence of barium.
abstract: The biotransformation of explosives has been investigated by many researchers. Bioremediation of soil and water contaminated with hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) is becoming the method of choice for clean-up of a variety of sites. In this study, we investigated biotransformation of RDX in the presence of barium. Ba is a metal commonly found in combination with RDX at sites requiring remediation. RDX was biotransformed by both a consortium of bacteria and an isolate from the consortium under anoxic conditions using a rich medium. However, Ba inhibited cell growth under both aerobic and anoxic conditions and slowed biotransformation rates by 40%. RDX and Ba inhibited growth of the isolate more than growth of the consortium. An additive inhibition model is proposed that accurately predicts the reduced growth rates observed.
authors.affiliation: Department of Chemical and Environmental Engineering, The University of Arizona, Tucson, 85721, USA.
authors.forename: Douglas M
authors.initials: DM
authors.lastname: Young
authors.forename: Karen
authors.initials: K
authors.lastname: Young
authors.forename: Kimberly L
authors.initials: KL
authors.lastname: Ogden
mesh_terms: D001464:Barium / Q000494:pharmacology*; D001711:Biotransformation; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D012706:Serratia marcescens / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism; D014227:Triazines / Q000378:metabolism*
chemical_list: D014227:Triazines; D001464:Barium; C009160:cyclonite