title: Distribution of subclasses mefA and mefE of the mefA gene among clinical isolates of macrolide-resistant (M-phenotype) Streptococcus pneumoniae, viridans group streptococci, and Streptococcus pyogenes.
abstract: The distribution of subclasses mefA and mefE of the mefA gene among 116 M-phenotype streptococci was as follows: pneumococci (38 strains had mefE and 4 mefA), viridans streptococci (49 mefE and 1 mefA), and Streptococcus pyogenes (24 mefA). Spain(9V)-3-14 and England(14)-9 clones of serotype 14 were dominant among pneumococci.
authors.affiliation: Servicio de Microbiologia. Hospital de Bellvitge, Feixa Llarga s/n, 08907 L'Hospitalet de Llobregat, Barcelona, Spain. c.ardanuy@csub.scs.es
authors.forename: Carmen
authors.initials: C
authors.lastname: Ardanuy
authors.forename: Fe
authors.initials: F
authors.lastname: Tubau
authors.forename: Josefina
authors.initials: J
authors.lastname: Liñares
authors.forename: María Angeles
authors.initials: MA
authors.lastname: Domínguez
authors.forename: Román
authors.initials: R
authors.lastname: Pallarés
authors.forename: Rogelio
authors.initials: R
authors.lastname: Martín
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics*; D024881:Drug Resistance, Bacterial; D004739:England; D005602:France; D006801:Humans; D018942:Macrolides / Q000494:pharmacology*; D008565:Membrane Proteins / Q000235:genetics*; D010641:Phenotype; D012703:Serotyping; D013030:Spain; D013290:Streptococcal Infections / Q000382:microbiology; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000235:genetics*; D013297:Streptococcus pyogenes / Q000187:drug effects* / Q000235:genetics*; D034363:Viridans Streptococci / Q000187:drug effects* / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D018942:Macrolides; C117866:MefA protein, Streptococcus; C431304:MefE protein, Streptococcus pneumoniae; D008565:Membrane Proteins