Celecoxib enhances brain tumour cell radiosensitivity leading to massive tumour necrosis.
Kang
K B
KB
Division of Medical Science, National Cancer Centre, Singapore.
Wang
T T
TT
Woon
C T
CT
Cheah
S T
ST
Lim
Y K
YK
Moore
X L
XL
Wong
M C
MC
D042683:Angiopoietin-1 / Q000378:metabolism; D042702:Angiopoietin-2 / Q000378:metabolism; D000818:Animals; D001932:Brain Neoplasms / Q000473:pathology* / Q000532:radiotherapy; D000068579:Celecoxib; D002470:Cell Survival / Q000187:drug effects / Q000528:radiation effects; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology*; D005909:Glioblastoma / Q000473:pathology* / Q000532:radiotherapy; D006801:Humans; D066298:In Vitro Techniques; D051379:Mice; D008819:Mice, Nude; D009336:Necrosis; D011720:Pyrazoles / Q000494:pharmacology*; D011836:Radiation Tolerance / Q000187:drug effects*; D013449:Sulfonamides / Q000494:pharmacology*; D014407:Tumor Cells, Cultured; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism
D042683:Angiopoietin-1; D042702:Angiopoietin-2; D016861:Cyclooxygenase Inhibitors; D011720:Pyrazoles; D013449:Sulfonamides; D042461:Vascular Endothelial Growth Factor A; D000068579:Celecoxib