title: Screening of dementia in stroke patients with lacunar infarcts: comparison of the mattis dementia rating scale and the mini-mental state examination.
abstract: There have been no data on the performance of the Initiation-Perseveration subtest of the Mattis Dementia Rating Scale (MDRS-IP) in screening poststroke dementia (PSDE). Three months after the index stroke, a research assistant administered the MDRS-IP and Mini-Mental State Examination (MMSE) to 83 Chinese stroke patients with lacunar infarcts who were consecutively admitted to the stroke unit of a general hospital. A psychiatrist, who was blind to the MDRS-IP and MMSE scores, interviewed all 83 patients and made a Diagnostic and Statistical Manual of Mental Disorders (4th edition) diagnosis of dementia, which served as the benchmark for judging the performance of MDRSIP. The optimal cutoff point of MDRS-IP was 22/23. The sensitivity, specificity, and positive and negative predictive values of MDRS-IP, and the area under the receiver operating characteristic curve were 82%, 90%, 0.41, 0.98, and 0.91, respectively. The overall performance of the MDRS-IP was comparable to the MMSE.
authors.affiliation: Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, SAR, China. tangwk@cuhk.edu.hk
authors.forename: Wai Kwong
authors.initials: WK
authors.lastname: Tang
authors.forename: Vincent
authors.initials: V
authors.lastname: Mok
authors.forename: Sandra S M
authors.initials: SS
authors.lastname: Chan
authors.forename: Helen F K
authors.initials: HF
authors.lastname: Chiu
authors.forename: Ka Sing
authors.initials: KS
authors.lastname: Wong
authors.forename: Timothy C Y
authors.initials: TC
authors.lastname: Kwok
authors.forename: Wynnie W M
authors.initials: WW
authors.lastname: Lam
authors.forename: Gabor S
authors.initials: GS
authors.lastname: Ungvari
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D020520:Brain Infarction / Q000150:complications* / Q000523:psychology; D016022:Case-Control Studies; D003704:Dementia / Q000175:diagnosis* / Q000209:etiology; D003937:Diagnosis, Differential; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D007406:Interview, Psychological; D008297:Male; D008609:Mental Status Schedule; D008875:Middle Aged; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D020521:Stroke / Q000150:complications* / Q000523:psychology