title: Midterm results of mitral valve repair with artificial chordae in children.
abstract: OBJECTIVE
  We have used artificial chordal replacement with expanded polytetrafluoroethylene sutures for mitral valve repair in children and reported favorable early clinical results. In this article we evaluate the midterm results of mitral valve repair with expanded polytetrafluoroethylene sutures in 39 children.
  
  
  METHODS
  From April 1995 through September 2003, mitral valve repair with chordal replacement using expanded polytetrafluoroethylene sutures was performed in 39 patients. In all patients the preoperative grade of mitral regurgitation was moderate or more because of prolapse of the anterior mitral leaflet. The mean age and body weight at the time of the operation were 4.7 +/- 5.3 years (range, 1 month to 17.8 years) and 14.4 +/- 12.2 kg (range, 3.9-54.4 kg), respectively. The number of expanded polytetrafluoroethylene sutures ranged from 1 to 3 (mean, 1.4). The mean follow-up period and body weight at the latest follow-up were 5.0 +/- 2.3 years (range, 1.1-8.5 years) and 25.7 +/- 16.4 kg (range, 6.9-73 kg), respectively.
  
  
  RESULTS
  There were no operative or late deaths. Only one patient required mitral valve replacement, which occurred 17 days after repair. Two patients underwent redo mitral valve repair 2 and 5 years after initial repair, respectively. The actuarial freedom from reoperation at 5 and 8 years was 94.8% and 89.5%, respectively. At the latest follow-up, trivial or less mitral regurgitation was observed in 33 (84.6%) patients.
  
  
  CONCLUSIONS
  Mitral valve repair with expanded polytetrafluoroethylene sutures in children demonstrated favorable midterm outcome. The procedure is safe and effective, with potential for patients' growth.
authors.affiliation: Department of Cardiovascular Surgery, Fukuoka Children's Hospital, Fukuoka, Japan.
authors.forename: Kazu
authors.initials: K
authors.lastname: Minami
authors.forename: Hideaki
authors.initials: H
authors.lastname: Kado
authors.forename: Sadahiro
authors.initials: S
authors.lastname: Sai
authors.forename: Hideki
authors.initials: H
authors.lastname: Tatewaki
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Shiokawa
authors.forename: Atsuhiro
authors.initials: A
authors.lastname: Nakashima
authors.forename: Koji
authors.initials: K
authors.lastname: Fukae
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Hirose
mesh_terms: D000293:Adolescent; D001783:Blood Flow Velocity / Q000502:physiology; D002648:Child; D002669:Child Welfare; D002675:Child, Preschool; D002815:Chordae Tendineae / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D007223:Infant; D007229:Infant Welfare; D008297:Male; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000601:surgery*; D008945:Mitral Valve Prolapse / Q000000981:diagnostic imaging / Q000601:surgery; D011138:Polytetrafluoroethylene / Q000627:therapeutic use; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality / Q000601:surgery; D012086:Reoperation; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome; D016277:Ventricular Function, Left / Q000502:physiology
chemical_list: D011138:Polytetrafluoroethylene