Effect of anionic salt and highly fermentable carbohydrate supplementations on urine pH and on experimentally induced hypocalcaemia in cows.
The objective of this experiment was to determine the effect of dietary grain on calcium homeostasis. Six rumen-fistulated dairy cows with 3 or more previous lactations and no history of parturient paresis were randomly assigned to a sequence of diets in a crossover study with 4 periods of 10 days each. Dietary treatments were: A control ration consisting of wrap grass silage alone (1), the control ration supplemented with ammonium chloride and ammonium sulphate salt solution (2), control ration following a period with supplementation (3) and control ration supplemented with increasing amounts of barley from 4 to 10 kg/cow per day, expected to produce subclinical rumen acidosis (4). Daily intake of the diets was adjusted to 14 kg DM/cow per day. On day 11, the calcium-regulating mechanisms in cows were challenged until recumbency by a standardized intravenous EDTA infusion and cows were left to recover spontaneously. Anion supplementation and the feeding of highly fermentable carbohydrate lowered urine pH below 7.0 due to subclinical acidosis. During spontaneous recovery from EDTA induced hypocalcaemia, the cows more quickly regained a whole blood free calcium concentration of 1.00 mmol/L if they had most recently been supplemented with either anionic salts or with increasing amounts of barley, as compared to the basic ration. It is concluded that so-called slug-feeding or 'steaming up' with highly fermentable carbohydrates before parturition in milk fever susceptible cows enhanced calcium homeostasis similar to the effect seen in cows on anionic diets.
Mellau
L S B
LS
Cattle Production Medicine Research Group, Department of Large Animal Sciences, The Royal Veterinary and Agricultural University, Denmark. mellau@suanet.ac.tz
Jørgensen
R J
RJ
Bartlett
P C
PC
Enemark
J M D
JM
Hansen
A K
AK
D000136:Acid-Base Equilibrium / Q000187:drug effects* / Q000502:physiology; D000643:Ammonium Chloride / Q000008:administration & dosage; D000645:Ammonium Sulfate / Q000008:administration & dosage; D000818:Animals; D000838:Anions / Q000008:administration & dosage*; D002118:Calcium / Q000097:blood / Q000378:metabolism*; D002417:Cattle; D002418:Cattle Diseases / Q000517:prevention & control*; D018592:Cross-Over Studies; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D019587:Dietary Supplements; D004492:Edetic Acid; D005260:Female; D005285:Fermentation; D001467:Hordeum; D006863:Hydrogen-Ion Concentration; D006996:Hypocalcemia / Q000139:chemically induced / Q000517:prevention & control / Q000662:veterinary*; D011897:Random Allocation; D012417:Rumen / Q000737:chemistry / Q000378:metabolism; D014556:Urine / Q000737:chemistry*
D000838:Anions; D004040:Dietary Carbohydrates; D000643:Ammonium Chloride; D004492:Edetic Acid; D000645:Ammonium Sulfate; D002118:Calcium