Potentiometric sensor for dipicolinic acid.
A potentiometric chemosensor for selective determination of dipicolinic acid (2,6-pyridinedicarboxylic acid, DPA) was developed based on the surface imprinting technique coupled with a nanoscale transducer: an indium tin oxide (ITO)-coated glass plate. The sensor fabrication conditions, optimal recognition condition, as well as selectivity, sensitivity, and stability of the DPA sensor have been investigated. The DPA sensor could recognize DPA from 3,5-pyridinedicarboxylic acid. Potentiometric measurements demonstrated selective detection of DPA in a concentration range of 1.5 x 10(-6) to 0.0194 M. The response time of DPA sensor for 4 x 10(-4) M DPA was 25 s. The potentiometric response of the DPA sensor to DPA is at 90% of its initial magnitude after 550 times measurement. The viability of such a modified ITO electrode in the presence of other inorganic, organic, and biological materials was probed.
Zhou
Yanxiu
Y
Polymer Research Institute, Polytechnic University, Six Metrotech Center, Brooklyn, NY 11201-3840, USA. yzhou@poly.edu
Yu
Bin
B
Levon
Kalle
K
D001408:Bacillus anthracis / Q000302:isolation & purification* / Q000378:metabolism*; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D020099:Coated Materials, Biocompatible / Q000737:chemistry; D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods*; D008422:Materials Testing; D008839:Microelectrodes; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods*; D010848:Picolinic Acids / Q000032:analysis*; D013499:Surface Properties; D017971:Tin Compounds / Q000737:chemistry*
D020099:Coated Materials, Biocompatible; D010848:Picolinic Acids; D017971:Tin Compounds; C109984:indium tin oxide; C004860:dipicolinic acid