title: Hemochromatosis mutations in Iranians with hepatitis B virus infection.
abstract: In this study, the frequencies of the common hemochromatosis gene mutations were assessed in 75 Iranian subjects with chronic hepatitis B infection. We found that the major C282Y mutation was significantly more frequent in subjects infected with hepatitis B virus (4%) than in 194 control subjects (0%, P=.02; Fisher's exact test).
authors.affiliation: Research Center for Gastroenterology and Liver Diseases, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Hossein
authors.initials: H
authors.lastname: Sendi
authors.forename: Tahereh
authors.initials: T
authors.lastname: Ghaziani
authors.forename: Mohammad R
authors.initials: MR
authors.lastname: Zali
authors.forename: Peyman
authors.initials: P
authors.lastname: Adibi
authors.forename: Mohammadreza
authors.initials: M
authors.lastname: Agah
authors.forename: Maryam
authors.initials: M
authors.lastname: Jazayeri
authors.forename: Saeed
authors.initials: S
authors.lastname: Shahraz
authors.forename: Lars
authors.initials: L
authors.lastname: Magnius
authors.forename: Herbert L
authors.initials: HL
authors.lastname: Bonkovsky
mesh_terms: D000328:Adult; D005260:Female; D020022:Genetic Predisposition to Disease; D006432:Hemochromatosis / Q000150:complications* / Q000235:genetics*; D000071020:Hemochromatosis Protein; D019694:Hepatitis B, Chronic / Q000150:complications* / Q000235:genetics; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006801:Humans; D007492:Iran; D008297:Male; D008565:Membrane Proteins / Q000235:genetics*; D009154:Mutation / Q000235:genetics*
chemical_list: C103673:HFE protein, human; D000071020:Hemochromatosis Protein; D015395:Histocompatibility Antigens Class I; D008565:Membrane Proteins