Long-term follow-up of oral tolerance induction with HLA-peptide B27PD in patients with uveitis.
Oral tolerance induction with peptide B27PD had an ameliorating effect in uveitis patients, which was also observed in the five-year follow-up period. Repeated treatments with peptide B27PD were also effective. Side effects did not occur in this patient group, not even in patients receiving peptide for up to 42 weeks.
Thurau
Stephan R
SR
Section of Immunobiology, Department of Ophthalmology, Ludwig-Maximilians-University, Mathildenstr. 8, 80336 Munich, Germany. Stephan.Thurau@med.uni-muenchen.de
Fricke
Harald
H
Burchardi
Christian
C
Diedrichs-Möhring
Maria
M
Wildner
Gerhild
G
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000595:Amino Acid Sequence; D005500:Follow-Up Studies; D015796:HLA-B27 Antigen / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance; D018928:Immunity, Mucosal; D010446:Peptide Fragments / Q000276:immunology* / Q000627:therapeutic use; D013997:Time Factors; D014605:Uveitis / Q000276:immunology* / Q000628:therapy; D014792:Visual Acuity / Q000276:immunology
D000276:Adjuvants, Immunologic; D015796:HLA-B27 Antigen; D010446:Peptide Fragments