[A primary study on antimicrobial and cytotoxic activity of marine bacteria].
Marine bacteria were isolated from marine organisms including invertebrates and seaweeds and from sea water and sediments of different sea area. Ethyl acetate extractions of marine bacterial fermentation were screened for antimicrobial and cytotoxicity activities by using the methods of agar diffusion and MTT assay, and the relationship of active bacteria and their origin was studied. The results showed that 42 strains among total 341 isolated marine bacteria had antimicrobial activity, and 7 strains had cytotoxicity activity. The proportion of active bacteria associated with marine invertebrates and seaweeds (22% and 11%) was higher than that isolated from sea water and sediments (7% and 5%). The most active marine bacteria were assigned to the Pseudomonas, Photobacterium, Clostridium, Alteromonas and Flavobacterium group.
Zheng
Li
L
Graduate School of Chinese Academy of Science, Beijing 100039, China. zhengli@ms.qdio.ac.cn
Lin
Wei
W
Yan
Xiaojun
X
Chen
Haimin
H
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D000903:Antibiotics, Antineoplastic / Q000096:biosynthesis*; D001419:Bacteria / Q000378:metabolism*; D012623:Seawater; D014871:Water Microbiology
D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic