title: Distribution of immunoreactivity of calcium-binding proteins in the rabbit piriform cortex.
abstract: The piriform cortex has been extensively studied due to its possible role in epileptogenic activity. Neurones containing calcium-binding proteins (CaBPs), as a component of inhibitory circuitry, seem to be critically involved in this pathological process. The aim of the present study was to characterise the pattern of distribution of CaBPs-immunoreactivity in the piriform cortex of the adult rabbit. It comprises labelled cells, fibres (often with varicosities) and terminals. It varies among the layers. Moreover, the distribution of the parvalbumin- and calretinin-immunoreactive fibres and terminals allows even further subdivision of the layer I into two sublayers. Calretinin-ir neurones are located in subpial (Ia) layer, while parvalbumin - as well as calbindin-D28k-ir ones are mainly located in the second and third layer. Cajal-Retzius-like neurones containing calretinin, Chandelier cells containing parvalbumin and basket cells containing calbindin D28k and parvalbumin can be distinguished among labelled subpopulations of CaBPs neurones. In general, the pattern of PV- CR- and CB-immunoreactivity is similar to that previously characterised in other mammals, i.e., rats, guinea pigs, hedgehog, and tenrecs. The pattern is organised in topographic fashion confirming the complexity of regulatory circuits in the rabbit piriform cortex.
authors.affiliation: Department of Anatomy and Neurobiology, Medical University of Gdańsk, Gdańsk, Poland. swoj@amedec.amg.gda.pl
authors.forename: Sławomir
authors.initials: S
authors.lastname: Wójcik
authors.forename: Jerzy
authors.initials: J
authors.lastname: Dziewiatkowski
authors.forename: Edyta
authors.initials: E
authors.lastname: Spodnik
authors.forename: Beata
authors.initials: B
authors.lastname: Ludkiewicz
authors.forename: Przemysław
authors.initials: P
authors.lastname: Kowiański
authors.forename: Jan Henryk
authors.initials: JH
authors.lastname: Spodnik
authors.forename: Janusz
authors.initials: J
authors.lastname: Morys
mesh_terms: D000818:Animals; D002135:Calcium-Binding Proteins / Q000378:metabolism*; D002540:Cerebral Cortex / Q000378:metabolism*; D007091:Image Processing, Computer-Assisted; D007150:Immunohistochemistry; D018613:Microscopy, Confocal; D009474:Neurons / Q000378:metabolism*; D011817:Rabbits
chemical_list: D002135:Calcium-Binding Proteins