title: [Changes in Japanese cedar sensitization rates of Japanese allergic children during the last 15 years].
abstract: In order to evaluate the changes in Japanese Cedar (JC) sensitization rates of allergic children, serum samples from 88 patients about 15 years ago (past group) and those from 91 current patients (present group) were randomly selected, and their JC specific IgE were measured with the CAP-RAST system. Sensitivity rate (class 2 or more) for JC of the present group was 65.9%, which was significantly higher than that of the past group, which was 46.6%. However, there was no significant difference between these two groups for children aged 6 or younger. For children aged 7 or older, the sensitivity rate of the present group was significantly higher than that of the past group. Thus, protection against JC sensitization, especially during early childhood, should be given serious attention.
authors.affiliation: Department of Pediatrics, Graduate School of Medicine, Kyoto University. kusu@kuhp.kyoto-u.ac.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Kusunoki
authors.forename: Takeshi
authors.initials: T
authors.lastname: Miyanomae
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Inoue
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Itoh
authors.forename: Takakazu
authors.initials: T
authors.lastname: Yoshioka
authors.forename: Ikuo
authors.initials: I
authors.lastname: Okafuji
authors.forename: Ryuta
authors.initials: R
authors.lastname: Nishikomori
authors.forename: Toshio
authors.initials: T
authors.lastname: Heike
authors.forename: Tatsutoshi
authors.initials: T
authors.lastname: Nakahata
mesh_terms: D000485:Allergens / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D032485:Cryptomeria; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D008297:Male; D011058:Pollen / Q000276:immunology*; D011852:Radioallergosorbent Test; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology*
chemical_list: D000485:Allergens; D007073:Immunoglobulin E