title: Linear accelerator-based radiosurgery for vestibular schwannoma.
abstract: Despite major advances in skull base surgery and microsurgical techniques, surgery for vestibular schwannoma (VS) carries a risk of complications. Some are inherent to general anesthesia and surgery of any type and include myocardial infarction, pneumonia, pulmonary embolism, and infection. Some are specific to neurosurgery in this area of the brain, and include hydrocephalus, cerebrospinal fluid leak, facial nerve paralysis, facial numbness, hearing loss, ataxia, dysphagia, and major stroke. Even in the hands of very experienced acoustic surgeons, these risks cannot be eliminated. Radiosurgery provides an outpatient, noninvasive alternative for the treatment of small acoustic schwannomas. Initially radiosurgery was undertaken in "high-risk" patients, including the elderly, those with severe medical comorbidities, and those in whom tumors recurred after surgery. Additionally, a high rate of cranial nerve morbidity was reported. With improvements in dosimetry planning and dose selection, however, authors practicing at radiosurgical centers now report very low complication rates, as well as high tumor control rates. In this report the authors specifically review the results of linear accelerator-based radiosurgery for VS and compare these outcomes with the best surgical alternatives.
authors.affiliation: Department of Neurosurgery, UFBI, University of Florida, Gainesville 32610, USA. friedman@neurosurgery.ufl.edu
authors.forename: William A
authors.initials: WA
authors.lastname: Friedman
authors.forename: Kelly D
authors.initials: KD
authors.lastname: Foote
mesh_terms: D006311:Hearing Disorders / Q000000981:diagnostic imaging / Q000517:prevention & control / Q000601:surgery; D006801:Humans; D009464:Neuroma, Acoustic / Q000000981:diagnostic imaging / Q000601:surgery*; D011859:Radiography; D016634:Radiosurgery / Q000295:instrumentation* / Q000379:methods*