A binaphthyl-containing Eu(III) complex and its interaction with human serum albumin: a luminescence study.
On binding to human serum albumin (HSA), the Eu(III) luminescent emission enhancement of a complex containing a binaphthyl chromophore enables the determination of binding constants, showing no chiral discrimination for the (R)- (K= 8200 +/- 810 M(-1)) and (S)-enantiomers (K= 7710 +/- 460 M(-1)).
Hamblin
Jacqueline
J
Department of Chemistry, University of Leicester, Leicester LE1 7RH, UK.
Abboyi
Neil
N
Lowe
Mark P
MP
D005063:Europium / Q000737:chemistry*; D006801:Humans; D008024:Ligands; D049408:Luminescent Agents / Q000138:chemical synthesis / Q000737:chemistry*; D008163:Luminescent Measurements; D046911:Macromolecular Substances / Q000138:chemical synthesis / Q000737:chemistry; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D011485:Protein Binding; D012709:Serum Albumin / Q000737:chemistry*
C510370:2,2'-bis(bromomethyl)-1,1'-binaphthyl; D008024:Ligands; D049408:Luminescent Agents; D046911:Macromolecular Substances; D009281:Naphthalenes; D009942:Organometallic Compounds; D012709:Serum Albumin; C031721:naphthalene; D005063:Europium