Mycobacterium gastri causing disseminated infection in children of same family.
Two children of the same family were admitted to the pediatric ward with a history of productive cough, nocturnal sweats, and weight loss. On physical examination, lymphadenopathy was seen on both sides of the neck and axillae. The sizes of the lymph nodes varied, and some showed fistula formation with drainage. A chest x-ray of the boy revealed diffuse nodular densities, while in the girl, peribronchial thickening in both lower lung zones and hilar adenopathy were detected. Sonography of the abdomen and pelvis in both cases showed multiple para-aortic adenopathies with hypodense centers. Microscopic examination of sputum, gastric washings, and node biopsy specimens proved positive for acid-fast bacilli. Systematic identification of acid-fast bacilli on Lowenstein-Jensen culture media identified the isolates as Mycobacterium gastri. These appear to be the first cases of pediatric infection and the fourth report of human infection caused by this atypical Mycobacterium.
Velayati
Ali Akbar
AA
Department of Pediatrics, National Research Institute of Tuberculosis and Lung Disease, Shaheed Beheshti University of Medical Sciences and Health Sciences, Darabad, Tehran, Iran.
Boloorsaze
Mohammad Reza
MR
Farnia
Parissa
P
Mohammadi
Foroozan
F
Karam
Mehrdad Bakshayesh
MB
Masjedi
Mohammad Reza
MR
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D018562:Disease Transmission, Infectious; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D008297:Male; D009161:Mycobacterium / Q000145:classification / Q000302:isolation & purification*; D009164:Mycobacterium Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology* / Q000635:transmission; D035781:Siblings; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents