title: Individual variation in semen parameters of healthy young volunteers.
abstract: Individual variation in semen parameters was investigated in healthy young volunteers. Semen samples were collected approximately once a month over a one-year period for a total of 93 samples (5 to 10 samples per subject) from 12 volunteers in their twenties. Semen analysis was carried out according to the WHO Manual. The amount of variation in each semen variable was calculated for each subject by dividing the maximum value by the minimum value. The results showed that the semen volume varied by 1.9+/-0.8 fold (1.3 to 4.2 fold), the sperm concentration by 4.8+/-4.3 fold (1.5 to 17.2 fold), the percentage of sperm with forward progression by 2.8+/-1.4 fold (1.6 to 6.4 fold), the percentage of sperm with rapid linear progression by 3.4+/-2.6 fold (1.7 to 10.9 fold), the percentage of sperm with normal morphology by 1.9+/-0.4 fold (1.3 to 2.4 fold), and the percentage of live sperm by 1.5+/-0.4 fold (1.1 to 2.6 fold). A between-group comparison showed significant differences in all of the variables except the percentage of sperm with normal morphology. These results suggest multiple and considerable semen analyses are needed when evaluating semen parameters.
authors.affiliation: Department of Urology, Teikyo University School of Medicine, Itabashi, Tokyo, Japan. oshios@rs.noda.tus.ac.jp
authors.forename: S
authors.initials: S
authors.lastname: Oshio
authors.forename: Y
authors.initials: Y
authors.lastname: Ashizawa
authors.forename: M
authors.initials: M
authors.lastname: Yotsukura
authors.forename: Y
authors.initials: Y
authors.lastname: Tohyama
authors.forename: M
authors.initials: M
authors.lastname: Iwabuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Adachi
authors.forename: H
authors.initials: H
authors.lastname: Matsuda
authors.forename: H
authors.initials: H
authors.lastname: Tomomasa
authors.forename: S
authors.initials: S
authors.lastname: Yoshida
authors.forename: K
authors.initials: K
authors.lastname: Takeda
authors.forename: T
authors.initials: T
authors.lastname: Umeda
mesh_terms: D000328:Adult; D019411:Clinical Laboratory Techniques / Q000592:standards*; D006801:Humans; D008297:Male; D011786:Quality Control; D012661:Semen / Q000166:cytology / Q000502:physiology*; D012680:Sensitivity and Specificity; D013076:Sperm Count / Q000592:standards; D013081:Sperm Motility; D013094:Spermatozoa / Q000002:abnormalities