Effects of retinoic acid on the inner cell mass in mouse blastocysts.
This is the first evidence that excess retinoic acid has a direct cellular response from proliferation to cell death (apoptosis) and affects in vitro development in mouse inner cell mass.
Huang
Fu-Jen
FJ
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Hsu
Yu-Cheng
YC
Kang
Hong-Yo
HY
Chang
Shiuh-Young
SY
Hsuuw
Yan-Der
YD
Huang
Ko-En
KE
D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D001755:Blastocyst / Q000187:drug effects* / Q000473:pathology; D049109:Cell Proliferation / Q000187:drug effects; D005260:Female; D051379:Mice; D008813:Mice, Inbred ICR; D011247:Pregnancy; D014212:Tretinoin / Q000633:toxicity*
D014212:Tretinoin