title: Isomerisation of aldoses in pyridine in the presence of aluminium oxide.
abstract: Addition of aluminium oxide to boiling pyridine solutions of D-xylose, L-arabinose, D-mannose and D-glucose strongly increased the reaction rate of the aldose-ketose transformation. The maximum content of 2-ketose was reached after less than 2h for the aldopentoses and 3h for the aldohexoses. D-Threo-2-pentulose (xylulose) was prepared from D-xylose, and isolated as its O-isopropylidene derivative, the yield was nearly twice that compared to that usually obtained in the classical Lobry de Bruyn-Alberda van Ekenstein transformation in pyridine.
authors.affiliation: Department of Chemistry, Biotechnology and Food Science, Section Chemistry, Agricultural University of Norway, As, Norway.
authors.forename: Dag
authors.initials: D
authors.lastname: Ekeberg
authors.forename: Svein
authors.initials: S
authors.lastname: Morgenlie
authors.forename: Yngve
authors.initials: Y
authors.lastname: Stenstrøm
mesh_terms: D000537:Aluminum Oxide / Q000737:chemistry*; D007536:Isomerism; D009005:Monosaccharides / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D009005:Monosaccharides; D011725:Pyridines; D000537:Aluminum Oxide; C023666:pyridine