title: [Vitamin B6 (Pyridoxine)--excessive dosage in food supplements and OTC medications].
abstract: Vitamin B6 (Pyridoxine) is sold in Israel as a supplement and is available over-the-counter (OTC) without regulation. High intake of this vitamin is found in patients with premenstrual syndrome, carpal tunnel syndrome, pregnancy associated nausea and vomiting, decreasing homocysteine levels and improving cognitive function. Mega-doses of this vitamin may result in intoxication. In this review we will outline vitamin B6 function, daily recommended intake, deficiency signs and patients in deficiency risk, and the clinical spectrum of vitamin B6 intoxication.
authors.affiliation: Rabin Medical Center, Beilinson Campus. nirbarak@post.tau.ac.il
authors.forename: Nir
authors.initials: N
authors.lastname: Barak
authors.forename: David
authors.initials: D
authors.lastname: Huminer
authors.forename: Bracha
authors.initials: B
authors.lastname: Stahl
mesh_terms: D019587:Dietary Supplements; D005260:Female; D006801:Humans; D004366:Nonprescription Drugs / Q000009:adverse effects* / Q000633:toxicity; D011247:Pregnancy; D011248:Pregnancy Complications; D025101:Vitamin B 6 / Q000009:adverse effects* / Q000633:toxicity
chemical_list: D004366:Nonprescription Drugs; D025101:Vitamin B 6