title: Palliative treatment of hepatocellular carcinoma with percutaneous ethanol injection using tumor's feeding artery occlusion under the ultrasonic color Doppler guidance.
abstract: We evaluate the efficacy of PEIT in patients with HCC using duplex color Doppler US. The study included 27 HCC patients admitted to the University Hospital Centre Zagreb, between 1993 and 1997. PEIT was performed for ablation of tumor supplying vessels in HCCs of < 5 cm in diameter, and as a palliative measure for tumor feeding vessel obliteration in larger tumors. The efficacy of PEIT was evaluated with duplex color Doppler US, and controlled by dynamic CT scan (16 patients) or selective angiography of hepatic artery (11 patients). All patients had well vascularized tumors before PEIT, and after therapy 25 of them showed absent or minimal tumor vascularization. Recanalization of the tumor feeding vessel was detected with Doppler US within 9 months after therapy. Study results suggested that duplex color Doppler US should be the method of choice in the evaluation of PEIT as well as in the follow-up of HCC patients after PEIT.
authors.affiliation: University Hospital Centre Zagreb, Department of Internal Medicine, Croatia. nadan.rustemovic@zg.htnet.hr
authors.forename: Nadan
authors.initials: N
authors.lastname: Rustemović
authors.forename: Boris
authors.initials: B
authors.lastname: Vucelić
authors.forename: Milorad
authors.initials: M
authors.lastname: Opacić
authors.forename: Rajko
authors.initials: R
authors.lastname: Ostojić
authors.forename: Roland
authors.initials: R
authors.lastname: Pulanić
authors.forename: Mladen
authors.initials: M
authors.lastname: Petrovecki
authors.forename: Branko
authors.initials: B
authors.lastname: Radanović
authors.forename: Jasna
authors.initials: J
authors.lastname: Marinić
authors.forename: Drazen
authors.initials: D
authors.lastname: Pulanić
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D004621:Embolization, Therapeutic; D000431:Ethanol / Q000008:administration & dosage* / Q000627:therapeutic use*; D005260:Female; D006499:Hepatic Artery; D006801:Humans; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D012997:Solvents / Q000008:administration & dosage* / Q000627:therapeutic use*; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex
chemical_list: D012997:Solvents; D000431:Ethanol