title: Comparative analysis of accumulation of chlorine e6 and hematoporphyrin derivatives in subpopulations of peripheral blood lymphocytes.
abstract: We studied accumulation of porphyrin photosensitizers chlorine e6, hematoporphyrin, and their derivatives by different lymphocyte subpopulations. The intensity of staining of B lymphocytes and natural killer cells with photosensitizers was higher compared to T lymphocytes. T cell subpopulation differed by their ability to bind photosensitizers. Relative accumulation of dimethyl esters of chlorine e6 and hematoporphyrin in cells surpassed that of nonesterified porphyrins.
authors.affiliation: Republican Research-and-Production Center for Child Oncology and Hematology, Minsk. savitskiy_v@yahoo.com
authors.forename: V P
authors.initials: VP
authors.lastname: Savitskii
authors.forename: V P
authors.initials: VP
authors.lastname: Zorin
authors.forename: M P
authors.initials: MP
authors.lastname: Potapnev
authors.forename: A Ya
authors.initials: AY
authors.lastname: Potapenko
mesh_terms: D016175:B-Lymphocyte Subsets / Q000378:metabolism; D002735:Chlorophyllides; D017324:Hematoporphyrin Derivative / Q000378:metabolism*; D006414:Hematoporphyrin Photoradiation; D006801:Humans; D016131:Lymphocyte Subsets / Q000378:metabolism*; D011166:Porphyrins / Q000378:metabolism*; D016176:T-Lymphocyte Subsets / Q000378:metabolism
chemical_list: D002735:Chlorophyllides; D011166:Porphyrins; C062985:phytochlorin; D017324:Hematoporphyrin Derivative