title: Multiple avascular necrosis in a patient with systemic lupus erythematosus/systemic sclerosis overlap syndrome.
abstract: A white female patient developed overlapping features of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) with severe pulmonary compromise. She was treated with steroids and azathioprine, which improved her clinical condition and spirometric status. In May 2002 she presented with continuous pain in her left ankle that continued even during rest and under treatment with nonsteroidal anti-inflammatory drugs (NSAIDs). Magnetic resonance imaging (MRI) showed multiple avascular necrosis (AVN). Rest and kinesitherapy were indicated for 1 year, and gradually an orthosis was introduced allowing the patient to walk normally.
authors.affiliation: Division of Rheumatology, Hospital de Clinicas José de San Martín, Faculty of Medicine, University of Buenos Aires, Argentina. pravier@hotmail.com
authors.forename: Javier Alberto
authors.initials: JA
authors.lastname: Cavallasca
authors.forename: Hugo Armando
authors.initials: HA
authors.lastname: Laborde
authors.forename: Mariela Beatriz
authors.initials: MB
authors.lastname: Araujo
authors.forename: Gustavo Guillermo
authors.initials: GG
authors.lastname: Nasswetter
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods; D020678:Microscopic Angioscopy; D009989:Orthotic Devices; D010020:Osteonecrosis / Q000150:complications / Q000175:diagnosis* / Q000534:rehabilitation; D010147:Pain Measurement; D018570:Risk Assessment; D012595:Scleroderma, Systemic / Q000150:complications / Q000175:diagnosis*; D012720:Severity of Illness Index; D013577:Syndrome; D014057:Tomography, X-Ray Computed