title: Large-scale changes in dendritic structure during reorganization of adult somatosensory cortex.
abstract: In adult rat somatosensory cortex (S1), neurons are biased and have less dendritic arbor close to the border between the forepaw and lower jaw representations. Changes in sensory experience cause changes in the functional organization of the neocortex. Therefore, we examined the morphology of neurons in the reorganized region of S1 after forepaw denervation. We found that during reorganization dendritic arbors changed to reflect the new location of the border.
authors.affiliation: Department of Psychology, University of California Riverside, Olmsted Hall 1344, Riverside, California 92521, USA. peter.hickmott@ucr.edu <peter.hickmott@ucr.edu>
authors.forename: Peter W
authors.initials: PW
authors.lastname: Hickmott
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Steen
mesh_terms: D000818:Animals; D001931:Brain Mapping; D002452:Cell Count / Q000379:methods; D048429:Cell Size; D003712:Dendrites / Q000378:metabolism / Q000473:pathology*; D003714:Denervation / Q000379:methods; D005552:Forelimb / Q000294:innervation* / Q000502:physiology; D066298:In Vitro Techniques; D007568:Jaw / Q000294:innervation* / Q000502:physiology; D008239:Lysine / Q000031:analogs & derivatives* / Q000378:metabolism; D008564:Membrane Potentials / Q000502:physiology; D009473:Neuronal Plasticity / Q000502:physiology*; D009474:Neurons / Q000378:metabolism / Q000473:pathology*; D018408:Patch-Clamp Techniques / Q000379:methods; D051381:Rats; D017207:Rats, Sprague-Dawley; D013003:Somatosensory Cortex / Q000166:cytology*; D013997:Time Factors
chemical_list: C013411:biocytin; D008239:Lysine