title: Intracranial haemorrhage as initial presentation of severe haemophilia B: case report and review of Mayo Clinic Comprehensive Hemophilia Center experience.
abstract: A neonate who had intracranial haemorrhage (ICH) at birth received a diagnosis of severe haemophilia B at 6 months of age. ICH had been the initial presentation of his bleeding disorder. His family history was negative for haemophilia. Review of our institutional experience as well as the literature indicates that intracranial bleeding as the initial presentation of haemophilia is rare.
authors.affiliation: Division of Pediatric Hematology/Oncology, Mayo Clinic, Rochester, MN, USA. rodriguez-vilmarie@mayo.edu
authors.forename: V
authors.initials: V
authors.lastname: Rodriguez
authors.forename: K A
authors.initials: KA
authors.lastname: Schmidt
authors.forename: J A
authors.initials: JA
authors.lastname: Slaby
authors.forename: R K
authors.initials: RK
authors.lastname: Pruthi
mesh_terms: D005164:Factor IX / Q000627:therapeutic use; D005260:Female; D002836:Hemophilia B / Q000150:complications* / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D020300:Intracranial Hemorrhages / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D007744:Obstetric Labor Complications; D009772:Obstetrical Forceps; D011247:Pregnancy; D014620:Vacuum Extraction, Obstetrical
chemical_list: D005164:Factor IX