title: Preoperative embolization of thyroid arteries in a patient with large multinodular goiter and papillary carcinoma.
abstract: We herein report the case of a 51-year-old woman, who presented with a large goiter (250-300 g on palpation) with extension to the mediastinum and compression of the trachea causing dyspnea and with associated lumbar pain. Although two fine-needle aspiration biopsies of the gland were negative, a biopsy of a lesion in the spine shown on computed tomography (CT) scan was positive for metastatic papillary thyroid carcinoma. Because of the extent of the goiter and the potential of significant blood loss, total thyroidectomy was considered to be high risk. In an attempt to reduce the goiter size and try to minimize surgical risks, preoperative embolization with polyvinyl alcohol in an emulsion with histoacryl particles was performed 7 days before surgery under conventional angiography. This procedure allowed a significant reduction in blood perfusion to the gland, which resulted in a decrease on the size of the goiter facilitating surgical removal of the gland.
authors.affiliation: SEMPR, Serviço de Endocrinologia e Metabologia do Hospital das Clínicas da Universidade Federal do Paraná, Curitiba, Brazil. ramoshelton@hotmail.com
authors.forename: Helton Estrela
authors.initials: HE
authors.lastname: Ramos
authors.forename: Milena
authors.initials: M
authors.lastname: Braga-Basaria
authors.forename: Calixto
authors.initials: C
authors.lastname: Haquin
authors.forename: Cléo O
authors.initials: CO
authors.lastname: Mesa
authors.forename: Lúcia de
authors.initials: Ld
authors.lastname: Noronha
authors.forename: Ronei
authors.initials: R
authors.lastname: Sandrini
authors.forename: Gisah de Amaral
authors.initials: Gde A
authors.lastname: Carvalho
authors.forename: Hans
authors.initials: H
authors.lastname: Graf
mesh_terms: D000792:Angiography; D001158:Arteries; D002291:Carcinoma, Papillary / Q000473:pathology / Q000601:surgery*; D004621:Embolization, Therapeutic; D005260:Female; D006044:Goiter, Nodular / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D011300:Preoperative Care; D013961:Thyroid Gland / Q000098:blood supply* / Q000000981:diagnostic imaging; D013964:Thyroid Neoplasms / Q000473:pathology / Q000601:surgery*