title: Corneal ulcers in two children wearing paragon corneal refractive therapy lenses.
abstract: OBJECTIVE
  To report the development of corneal ulcers in two children wearing Paragon Corneal Refractive Therapy (CRT) lenses.
  
  
  METHODS
  Two case reports of children who developed corneal ulcers when fit with Paragon CRT contact lenses, which were worn nightly, are discussed. Each patient presented with a bacterial corneal ulcer after wearing CRT contact lenses for less than 6 months. In the first patient, Pseudomonas aeruginosa was identified as the causative organism. In the second patient, Haemophilus influenza was cultured from the ulcer.
  
  
  RESULTS
  Both patients were treated with intensive, fortified antibiotics with rapid resolution of the corneal ulcers and preservation of vision. No surgical intervention was required.
  
  
  CONCLUSIONS
  Paragon CRT lenses have been approved for use in patients of all ages. When used in children, these lenses may present unique problems. The absolute incidence of bacterial corneal ulcers in patients with CRT lenses are unknown. Severe caution should be used before prescribing CRT lenses for children and informed consent should include potential sight-threatening corneal ulcers.
authors.affiliation: Division of Ophthalmology, Evanston Northwestern Healthcare, Chicago, Illinois, USA. mmacsai@enh.org
authors.forename: Marian S
authors.initials: MS
authors.lastname: Macsai
mesh_terms: D002648:Child; D003261:Contact Lenses / Q000009:adverse effects*; D003315:Cornea / Q000503:physiopathology*; D003320:Corneal Ulcer / Q000209:etiology* / Q000382:microbiology; D005260:Female; D006192:Haemophilus Infections / Q000209:etiology; D006193:Haemophilus influenzae; D006801:Humans; D008297:Male; D011552:Pseudomonas Infections / Q000209:etiology; D011550:Pseudomonas aeruginosa; D012030:Refractive Errors / Q000503:physiopathology* / Q000628:therapy*