title: Florfenicol-chloramphenicol exporter gene fexA is part of the novel transposon Tn558.
abstract: The florfenicol-chloramphenicol exporter gene fexA is part of the novel transposon Tn558 from Staphylococcus lentus. Similarities between Tn558 and Tn554 from Staphylococcus aureus included the arrangement of the transposase genes tnpA to -C and an att554-like target sequence. Circular forms of Tn558 were detected and suggest the functional activity of this transposon.
authors.affiliation: Institut für Tierzucht, Bundesforschungsanstalt für Landwirtschaft (FAL), Höltystr. 10, 31535 Neustadt-Mariensee, Germany.
authors.forename: Corinna
authors.initials: C
authors.lastname: Kehrenberg
authors.forename: Stefan
authors.initials: S
authors.lastname: Schwarz
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics; D002701:Chloramphenicol / Q000494:pharmacology*; D004251:DNA Transposable Elements / Q000235:genetics*; D005798:Genes, Bacterial / Q000235:genetics*; D026901:Membrane Transport Proteins / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013210:Staphylococcus / Q000187:drug effects* / Q000235:genetics*; D013839:Thiamphenicol / Q000031:analogs & derivatives* / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D004251:DNA Transposable Elements; C498061:FexA protein, Staphylococcus lentus; D026901:Membrane Transport Proteins; C112068:TnpA protein, Streptococcus; D002701:Chloramphenicol; C035534:florfenicol; D013839:Thiamphenicol