Update on treatment modalities for optic nerve sheath meningiomas.
Optic nerve sheath meningiomas (ONSMs) represent 1 to 2% of all meningiomas and one third of all optic nerve tumors. The management of ONSMs is controversial. Traditional surgical removal often results in postoperative blindness in the affected eye and thus has been abandoned as a treatment option in most patients. Surgery may be unnecessarily aggressive, especially if the patient has useful vision. When these tumors are left untreated, however, ensuing progressive visual impairment may lead to complete blindness. More recently, radiotherapy has gained wider acceptance as a treatment for these lesions. The authors of some reports have suggested that fractionated stereotactic radiosurgery (SRS) may be the best option for treating primary ONSMs. In patients with documented progressive visual deterioration, fractionated SRS may be effective in improving or stabilizing remaining functional vision. The authors review the clinical presentation, radiographic characteristics, and management of ONSMs, emphasizing the use of fractionated SRS.
Liu
James K
JK
Department of Neurosurgery, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Forman
Scott
S
Moorthy
Chitti R
CR
Benzil
Deborah L
DL
D006801:Humans; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000601:surgery*; D008579:Meningioma / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000601:surgery*; D019574:Optic Nerve Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000601:surgery; D011859:Radiography; D014786:Vision Disorders / Q000000981:diagnostic imaging / Q000517:prevention & control / Q000601:surgery; D014785:Vision, Ocular