title: The disease profile of poverty: morbidity and mortality in northern Uganda in the context of war, population displacement and HIV/AIDS.
abstract: The population of Gulu District (northern Uganda) has been severely incapacitated by war, epidemics and social disruption. This study is aimed at describing disease patterns and trends in this area through a retrospective analysis of discharge records for 155205 in-patients of Lacor Hospital in the period 1992-2002. The burden of infectious diseases in childhood is overwhelming, with malaria accounting for the steepest increase in admissions. Admissions for war-related injuries and malnutrition fluctuated with the intensity of the war and the severity of famine. Emerging and re-emerging infections, such as HIV/AIDS, tuberculosis and Ebola, accounted for a heavy disease burden; however, there has been a trend for admissions related to HIV/AIDS and tuberculosis to decrease since the implementation of community-based services. Vulnerable groups (infants, children and women) accounted for 79.8% of admissions. Long-term war, population displacement, the collapse of social structures and the breakdown of the health system place people at a much greater risk of persistent, emerging and re-emerging infectious diseases, malnutrition and war-related injuries, shaping the 'disease profile of poverty'. Most of the disease burden results from infectious diseases of childhood, whose occurrence could be dramatically reduced by low-cost and effective preventive and curative interventions.
authors.affiliation: Istituto Superiore di Sanità, National Centre for Epidemiology, Surveillance and Health Promotion, Viale Regina Elena 299, 00161 Rome, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Accorsi
authors.forename: M
authors.initials: M
authors.lastname: Fabiani
authors.forename: B
authors.initials: B
authors.lastname: Nattabi
authors.forename: B
authors.initials: B
authors.lastname: Corrado
authors.forename: R
authors.initials: R
authors.lastname: Iriso
authors.forename: E O
authors.initials: EO
authors.lastname: Ayella
authors.forename: B
authors.initials: B
authors.lastname: Pido
authors.forename: P A
authors.initials: PA
authors.lastname: Onek
authors.forename: M
authors.initials: M
authors.lastname: Ogwang
authors.forename: S
authors.initials: S
authors.lastname: Declich
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology* / Q000401:mortality; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003141:Communicable Diseases / Q000453:epidemiology* / Q000401:mortality; D017281:Cost of Illness; D004196:Disease Outbreaks; D005260:Female; D006760:Hospitalization / Q000639:trends; D006801:Humans; D007223:Infant; D007902:Length of Stay; D008288:Malaria / Q000453:epidemiology / Q000401:mortality; D008875:Middle Aged; D009017:Morbidity; D009748:Nutrition Disorders / Q000453:epidemiology / Q000401:mortality; D011014:Pneumonia / Q000453:epidemiology / Q000401:mortality; D011203:Poverty; D012189:Retrospective Studies; D014376:Tuberculosis / Q000453:epidemiology / Q000401:mortality; D014454:Uganda / Q000453:epidemiology; D014857:Warfare; D014947:Wounds and Injuries / Q000453:epidemiology / Q000401:mortality