title: Large bowel obstruction in women with pelvic malignancies. What is the primary?
abstract: BACKGROUND
  Large bowel obstruction is occasionally the mode of presentation of advanced colorectal or pelvic malignancies, and a prognostic of poor survival. The choices of treatment range from palliative tube decompression to curative or palliative surgery.
  
  
  METHODS
  Twelve out of 500 women with various malignancies and symptomatology of large bowel obstruction were studied. All patients required urgent exploratory laparotomies.
  
  
  RESULTS
  The primary site was established intra-operatively to be the colon (2 cases), stomach (2 cases) and ovaries (2 cases). In the remaining 6 cases there was uncertainty about the origin of primary disease. Routine histology and immuno-histochemistry of the specimens revealed the origin of primary malignancy in all cases.
  
  
  CONCLUSIONS
  Meticulous histological examination is essential for the establishment of correct diagnosis and selection of the best available treatment in women with pelvic malignancies, presenting with acute bowel obstruction.
authors.affiliation: 1st Propedeutical Department of Surgery, Aristotle University, AHEPA Hospital, Thessaloniki, Greece. jimkam@med.auth.gr
authors.forename: C
authors.initials: C
authors.lastname: Papapolychroniadis
authors.forename: D
authors.initials: D
authors.lastname: Kaimakis
authors.forename: K
authors.initials: K
authors.lastname: Giannoulis
authors.forename: P
authors.initials: P
authors.lastname: Berovalis
authors.forename: P
authors.initials: P
authors.lastname: Fotiadis
authors.forename: P
authors.initials: P
authors.lastname: Maidatsi
authors.forename: A
authors.initials: A
authors.lastname: Zaralidou
authors.forename: G
authors.initials: G
authors.lastname: Kokkonis
authors.forename: P
authors.initials: P
authors.lastname: Papakonstantinou
authors.forename: M
authors.initials: M
authors.lastname: Giala
authors.forename: N
authors.initials: N
authors.lastname: Harlaftis
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015994:Incidence; D007415:Intestinal Obstruction / Q000453:epidemiology* / Q000209:etiology* / Q000601:surgery; D007420:Intestine, Large / Q000473:pathology*; D007813:Laparotomy / Q000379:methods; D008875:Middle Aged; D009367:Neoplasm Staging; D010166:Palliative Care / Q000379:methods*; D010386:Pelvic Neoplasms / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment; D016019:Survival Analysis