title: [Volume and echostructure of the thyroid and ioduria in an urban population of adults in the southeastern Polish city of Rzeszów].
abstract: The aim of this work was to determine the volume and echostructure of the thyroid and to examine urinary iodine excretion in an adult population of residents of Rzeszów, a city located in the Carpathian endemic region for goiter, after the introduction of mandatory iodine prophylaxis in 1997. 984 subjects, aged 19-60, were examined (540 females and 394 males). The mean level of urinary iodine in the examined population was 104.17 microg/l (+/- 85.22). Higher urinary iodine levels were seen in the group of males (p = 0.005) and in those who were taking medication containing iodine (p = 0.002). The mean volume of the thyroid in the examined group was 18.69 (+/- 10.01) ml and was larger in the group of males than females (p < 0.005). Nodular lesions were found in 17% of the examined thyroids and a statistically significant prevalence in the group of females (20.8%) over the group of males (11.4%) was found (p < 0.0005). The occurrence of nodules increased with age and was significantly higher in the 40-60 year age group than in the 19-25 years age group (p = 0.001). In single--and multi--factor analysis, a correlation was found between the occurrence of nodules and the female gender (r-2.04, 3.48; p < 0.005, < 0.0005) and the occurrence of nodules and the volume of the thyroid (r-1.1, 1.11; p < 0.005, < 0.0005). The occurrence of nodules did not correlate with ioduria (r-1, p = 0.8). Iodine prophylaxis was shown to be highly effective, although the examined region does not yet meet the criteria for the elimination of iodine deficiency as formulated by the ICCIDD.
authors.affiliation: Oddział Chorób Wewnetrznych Szpitala Wojewódzkiego nr 2 w Rzeszowie. Florek9@op.pl
authors.forename: Renata
authors.initials: R
authors.lastname: Orłowska-Florek
authors.forename: Marek
authors.initials: M
authors.lastname: Grzywa
mesh_terms: D000328:Adult; D002391:Catchment Area, Health; D005260:Female; D006042:Goiter / Q000517:prevention & control* / Q000652:urine*; D006801:Humans; D007455:Iodine / Q000652:urine*; D008297:Male; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D015995:Prevalence; D016606:Thyroid Nodule / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000652:urine; D014463:Ultrasonography; D014505:Urban Population / Q000706:statistics & numerical data*
chemical_list: D007455:Iodine