title: Quantal transmission: not just for neurons.
abstract: Glia have moved into the spotlight as participants in synaptic signaling. Recent work by Bergles and colleagues extends this active role by showing that oligodendrocyte precursors cells (OPCs) in the hippocampus receive functional glutamatergic and GABAergic synapses. Synaptic signaling in these cells could provide a mechanism for activity-dependent modulation of OPC proliferation and differentiation.
authors.affiliation: Vollum Institute, L474, Oregon Health & Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA. overstre@ohsu.edu
authors.forename: Linda S
authors.initials: LS
authors.lastname: Overstreet
mesh_terms: D000818:Animals; D002450:Cell Communication / Q000502:physiology; D018698:Glutamic Acid / Q000378:metabolism; D009433:Neural Inhibition; D009474:Neurons / Q000502:physiology*; D009836:Oligodendroglia / Q000502:physiology; D013234:Stem Cells / Q000502:physiology; D013569:Synapses / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
chemical_list: D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid