title: Late occurrence of bilateral tuberculous-like epididymo-orchitis after intravesical bacille Calmette-Guérin therapy for superficial bladder carcinoma.
abstract: We report a case of bilateral tuberculous-like epididymo-orchitis occurring 3 years after intravesical bacille Calmette-Guérin instillation therapy in an 83-year-old patient with proven superficial bladder carcinoma. The patient had no previous history of tuberculosis. Because of persistent inflammation and painful swelling of the epididymides and testes, the patient underwent bilateral orchiectomy. This case demonstrates the late adverse effects that can occur after intravesical BCG therapy, which in our patient ended in surgical removal of both gonads.
authors.affiliation: Department of Urology, University of Innsbruck, Innsbruck, Austria. claudia.schaber@uibk.ac.at
authors.forename: C
authors.initials: C
authors.lastname: Falkensammer
authors.forename: C
authors.initials: C
authors.lastname: Gozzi
authors.forename: M
authors.initials: M
authors.lastname: Hager
authors.forename: H
authors.initials: H
authors.lastname: Maier
authors.forename: G
authors.initials: G
authors.lastname: Bartsch
authors.forename: L
authors.initials: L
authors.lastname: Höltl
authors.forename: P
authors.initials: P
authors.lastname: Rehder
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy / Q000601:surgery; D000283:Administration, Intravesical; D000368:Aged; D000369:Aged, 80 and over; D001500:BCG Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D002278:Carcinoma in Situ / Q000628:therapy; D002295:Carcinoma, Transitional Cell / Q000628:therapy; D003131:Combined Modality Therapy; D004823:Epididymitis / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007322:Instillation, Drug; D008297:Male; D009163:Mycobacterium bovis / Q000302:isolation & purification*; D009378:Neoplasms, Multiple Primary; D009919:Orchiectomy; D009920:Orchitis / Q000209:etiology* / Q000601:surgery; D011471:Prostatic Neoplasms / Q000532:radiotherapy / Q000601:surgery; D013997:Time Factors; D020728:Transurethral Resection of Prostate; D014375:Tuberculoma / Q000209:etiology / Q000601:surgery; D014389:Tuberculosis, Male Genital / Q000209:etiology* / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000628:therapy
chemical_list: D001500:BCG Vaccine