Toxic epidermal necrolysis syndrome--management and case report.
Toxic epidermal necrolysis syndrome [known also as Lyell's syndrome] is a severe drug reaction, characterized by fever. systemic toxicity, extensive skin rash with blisters and exfoliation similar to that of major burns. It carries an average mortality rate of 25%. The data concerning most frequent triggering agents and the differential diagnosis is presented; An overview of the management protocol for these patient in the Burn Center of the Lebanese Hospital is exposed with a case presentation of a young woman who sustained a 95% body surface area [BSA] cutaneous loss after the ingestion of only 2 tablets of amoxycilline documented by the complication and evolution.
Najem
J C
JC
Department of Anesthesiology, Burn Center, Lebanese Hospital, Beirut.
Raphael
N
N
Ghanime
G
G
Karam
R
R
Tohme
H
H
Moukarzel
Z
Z
Achy
J
J
D000328:Adult; D000658:Amoxicillin / Q000009:adverse effects; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*
D000900:Anti-Bacterial Agents; D000658:Amoxicillin