title: Evaluation of copper supplementation to control Haemonchus contortus infections of sheep in Sweden.
abstract: A pen study was conducted to assess the effect of providing daily copper mineral supplement, or copper wire particle (COWP) capsules, on established or incoming mixed nematode infections in young sheep. For lambs with established (6 week old) infections, COWP resulted in 97% and 56% reduction of the adult and early L4 stages of H. contortus, respectively, compared with controls (p<0.001). Additionally there was a 74% reduction in Teladorsagia circumcincta infections in the COWP lambs compared with controls (p<0.01). However, no effect was observed when COWP were given at the commencement of a larval dosing period of 6 weeks. There was no significant effect of copper mineral supplement (given at the recommended rate to prevent Cu deficiency) on either established, or developing parasite infections. In addition, a field trial was conducted on a commercial farm to assess the effects of COWP in the management of recurrent H. contortus infections, but lack of parasites during the grazing season prevented an adequate assessment from being made. These results indicate that there is little, if any, benefit from a parasite control standpoint in recommending copper therapy, specifically to control parasites in Swedish sheep flocks.
authors.affiliation: Department of Parasitology (SWEPAR), National Veterinary Institute and Swedish University of Agricultural Sciences, Uppsala, Sweden. Peter.Waller@sva.se
authors.forename: P J
authors.initials: PJ
authors.lastname: Waller
authors.forename: G
authors.initials: G
authors.lastname: Bernes
authors.forename: L
authors.initials: L
authors.lastname: Rudby-Martin
authors.forename: B L
authors.initials: BL
authors.lastname: Ljungström
authors.forename: A
authors.initials: A
authors.lastname: Rydzik
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D000871:Anthelmintics / Q000008:administration & dosage / Q000627:therapeutic use*; D003300:Copper / Q000008:administration & dosage / Q000627:therapeutic use*; D019587:Dietary Supplements; D005260:Female; D006188:Haemonchiasis / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary*; D006189:Haemonchus; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy* / Q000517:prevention & control; D016896:Treatment Outcome
chemical_list: D000871:Anthelmintics; D003300:Copper