title: Perianal apocrine adenocarcinoma arising in a benign apocrine adenoma; first case report and review of the literature.
abstract: Benign apocrine lesions have been described in the anogenital region, although according to the World Health Organisation convincing examples of anal apocrine adenocarcinomas have not been published. This report describes the case of an invasive apocrine adenocarcinoma arising in a benign adenoma in the perianal region of a 45 year old woman. The origin and invasiveness are supported by histological and immunohistochemical studies.
authors.affiliation: Department of Laboratory Medicine and Pathology, University of Toronto, Toronto, Ontario M9G 1L5, Canada. karenmacneill@yahoo.com
authors.forename: K N
authors.initials: KN
authors.lastname: MacNeill
authors.forename: R H
authors.initials: RH
authors.lastname: Riddell
authors.forename: D
authors.initials: D
authors.lastname: Ghazarian
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D006607:Adenoma, Sweat Gland / Q000473:pathology*; D001005:Anus Neoplasms / Q000473:pathology*; D001050:Apocrine Glands / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D013544:Sweat Gland Neoplasms / Q000473:pathology*