title: Vaginal hysterectomy and abdominal hysterectomy for treatment of endometrial cancer in the elderly.
abstract: OBJECTIVE
  The purpose of this study was to analyze the outcome of vaginal and abdominal hysterectomy for treatment of endometrial cancer in elderly patients.
  
  
  METHODS
  In a retrospective series of 171 patients with age > or =70 years and at stages I-III, we evaluated operative and hospitalization data, as well as morbidity, mortality, and long-term survival associated with vaginal and abdominal hysterectomy. A total of 128 patients were operated on with vaginal hysterectomy and 43 cases underwent abdominal hysterectomy.
  
  
  RESULTS
  Medically compromised patients were significantly more frequent in the vaginal surgery group (P = 0.01). Overall, the 10-year disease-specific survival rates after vaginal and abdominal hysterectomy were 80% and 78%, respectively (P = n.s.). Limiting the analysis to stage I (130 patients), 10-year disease-specific survival was 83% in 95 women operated on by the vaginal route and 84% in 35 patients operated by the abdominal approach (P = n.s.). Patients in the vaginal surgery group had a significantly shorter operative time (P = 0.01), less blood loss (P < 0.05), and were discharged earlier (P < 0.05). Severe complications occurred in 5.4% of the vaginal and in 7.0% of the abdominal procedures. Perioperative mortality was zero after vaginal hysterectomy and 2.3% after abdominal hysterectomy, respectively.
  
  
  CONCLUSIONS
  Vaginal hysterectomy showed a high cure rate, shorter operative time, less blood loss, reduced morbidity, and no mortality and therefore may be considered the elective approach for treatment of elderly patients with endometrial cancer.
authors.affiliation: Department of Gynecology, Perinatology and Human Reproduction, University of Florence, Viale Morgagni 85, 50134 Florence, Italy. tommaso.susini@unifi.it
authors.forename: Tommaso
authors.initials: T
authors.lastname: Susini
authors.forename: Giambattista
authors.initials: G
authors.lastname: Massi
authors.forename: Gianni
authors.initials: G
authors.lastname: Amunni
authors.forename: Carlo
authors.initials: C
authors.lastname: Carriero
authors.forename: Mauro
authors.initials: M
authors.lastname: Marchionni
authors.forename: Gianluigi
authors.initials: G
authors.lastname: Taddei
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Scarselli
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016889:Endometrial Neoplasms / Q000601:surgery*; D005260:Female; D006801:Humans; D007045:Hysterectomy, Vaginal / Q000009:adverse effects / Q000379:methods*; D009017:Morbidity; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome