title: Polystyrene-supported (R)-2-piperazino-1,1,2-triphenylethanol: a readily available supported ligand with unparalleled catalytic activity and enantioselectivity.
abstract: A very active and highly enantioselective catalytic resin, designed for minimal perturbation of the catalytic center by the polymer matrix, has been assembled in two steps from (S)-triphenylethylene oxide, piperazine, and Merrifield resin and tested in the enantioselective ethylation of aldehydes. 1-Arylpropanols of 94-95% ee are obtained in high yield by the use of only 2 mol % of catalytic resin at 0 degrees C for 4 h.
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), 43007 Tarragona, Spain.
authors.forename: David
authors.initials: D
authors.lastname: Castellnou
authors.forename: Lluís
authors.initials: L
authors.lastname: Solà
authors.forename: Ciril
authors.initials: C
authors.lastname: Jimeno
authors.forename: José M
authors.initials: JM
authors.lastname: Fraile
authors.forename: José A
authors.initials: JA
authors.lastname: Mayoral
authors.forename: Antoni
authors.initials: A
authors.lastname: Riera
authors.forename: Miquel A
authors.initials: MA
authors.lastname: Pericàs