title: Preliminary study of the in vitro interaction between alcohol, high-dose flunitrazepam and its three metabolites using human liver microsomes.
authors.affiliation: Institute of Community Medicine, University of Tsukuba, Ibaraki-ken 305-8575, Japan. einosuke@md.tsukuba.ac.jp
authors.forename: Einosuke
authors.initials: E
authors.lastname: Tanaka
authors.forename: Takako
authors.initials: T
authors.lastname: Nakamura
authors.forename: Tasaru
authors.initials: T
authors.lastname: Terada
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Shinozuka
authors.forename: Katsuya
authors.initials: K
authors.lastname: Honda
mesh_terms: D014151:Anti-Anxiety Agents / Q000493:pharmacokinetics*; D001711:Biotransformation; D002492:Central Nervous System Depressants / Q000494:pharmacology*; D002851:Chromatography, High Pressure Liquid; D004347:Drug Interactions; D000431:Ethanol / Q000494:pharmacology*; D005445:Flunitrazepam / Q000493:pharmacokinetics*; D006801:Humans; D066298:In Vitro Techniques; D008862:Microsomes, Liver / Q000201:enzymology / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D014151:Anti-Anxiety Agents; D002492:Central Nervous System Depressants; D000431:Ethanol; D005445:Flunitrazepam