Effect of Nigerian citrus (Citrus sinensis Osbeck) honey on ethanol metabolism.
The effect of Nigerian citrus (Citrus sinensis Osbeck) honey on ethanol metabolism was tested using 45 consenting individuals in apparent good health and between the ages of 25 and 35 years. The subjects were moderate social drinkers matched in terms of body weight and build. The results obtained showed that on average, honey significantly (p < 0.05) increased the blood ethanol clearance rate by 68% and decreased the intoxication period by 43%, but insignificantly (p > 0.05) reduced the degree of intoxication by 9%. Honey could be a promising anti-intoxicating agent, but its long-term biochemical evaluation, possibly as a complement in the management of alcohol intoxication, deserves further study.
Onyesom
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Department of Biochemistry, Delta State University, Abraka, Nigeria.
D000284:Administration, Oral; D000328:Adult; D000435:Alcoholic Intoxication / Q000378:metabolism / Q000517:prevention & control*; D001628:Beverages; D001835:Body Weight; D032084:Citrus sinensis / Q000737:chemistry; D016903:Drug Monitoring; D000431:Ethanol / Q000378:metabolism*; D005260:Female; D005632:Fructose / Q000032:analysis; D005947:Glucose / Q000032:analysis; D006722:Honey / Q000032:analysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D016488:Medicine, African Traditional; D008657:Metabolic Clearance Rate; D009549:Nigeria; D012727:Sex Characteristics; D013395:Sucrose / Q000032:analysis; D013997:Time Factors; D014867:Water / Q000032:analysis
D014867:Water; D005632:Fructose; D000431:Ethanol; D013395:Sucrose; D005947:Glucose