title: Myocardial salvage in patients with non-ST-elevation myocardial infarction determined by myocardial perfusion imaging.
abstract: We compared acute and late myocardial perfusion imaging using technetium-99m isotopes in 69 patients who had non-ST-elevation myocardial infarction. Among these patients, we found that the ischemic risk area was often large (19% of the left ventricle), and that 67% had significant myocardial salvage, defined as a >25% decrease in risk area, which was associated with an improved ejection fraction.
authors.affiliation: Department of Department of Internal Medicine, Cardiology Division, Virginia Commonwealth University, Richmond, Virginia, USA. mkontos@hsc.vcu.edu
authors.forename: Michael C
authors.initials: MC
authors.lastname: Kontos
authors.forename: Karen A
authors.initials: KA
authors.lastname: Kurdziel
authors.forename: Joseph P
authors.initials: JP
authors.lastname: Ornato
authors.forename: Robert L
authors.initials: RL
authors.lastname: Jesse
authors.forename: James L
authors.initials: JL
authors.lastname: Tatum
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D009943:Organophosphorus Compounds / Q000627:therapeutic use; D015609:Organotechnetium Compounds / Q000627:therapeutic use; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon; D016896:Treatment Outcome
chemical_list: D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C078700:technetium tc-99m tetrofosmin; D017256:Technetium Tc 99m Sestamibi