title: The spanish connection: transcription and mRNA processing get even closer.
abstract: The synthesis of mRNA by RNA polymerase II appears coupled to numerous RNA-processing events, based on physical or functional connections revealed by biochemical or genetic tests. New findings were presented at a recent meeting in Spain that begin to illuminate the mechanisms underlying the connections between mRNA processing and specific steps in transcription (initiation, elongation, and termination) as well as recombination.
authors.affiliation: Department of Molecular Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA. ares@biology.ucsc.edu
authors.forename: Manuel
authors.initials: M
authors.lastname: Ares
authors.forename: Nick J
authors.initials: NJ
authors.lastname: Proudfoot
mesh_terms: D005057:Eukaryotic Cells / Q000378:metabolism; D009690:Nucleic Acid Conformation; D012319:RNA Polymerase II / Q000378:metabolism*; D012323:RNA Processing, Post-Transcriptional / Q000502:physiology*; D012326:RNA Splicing / Q000502:physiology*; D012333:RNA, Messenger / Q000378:metabolism*; D013030:Spain; D014158:Transcription, Genetic; D039221:mRNA Cleavage and Polyadenylation Factors / Q000378:metabolism
chemical_list: D012333:RNA, Messenger; D039221:mRNA Cleavage and Polyadenylation Factors; D012319:RNA Polymerase II