Efficient asymmetric synthesis of [7]helicene bisquinones.
The efficient one-pot six-step domino process which occurs when (SS)-2-(p-tolylsulfinyl)-1,4-benzoquinone (1) reacts with 3,6-divinyl-1,2,7,8-tetrahydrophenanthrenes 2a-c allowed enantioselective access to [7]helicene bisquinones 3a-c with excellent optical purities (96 to > 99% ee).
Carreño
M Carmen
MC
Departamento de Química Orgánica, Universidad Autónoma de Madrid, Cantoblanco, 28049-Madrid, Spain. carmen.carrenno@uam.es
González-López
Marcos
M
Urbano
Antonio
A