Bone marrow transplantation for leukaemia--current status and strategies for improvement.
Thirty-five years ago, bone marrow transplantation was first being explored as a last-ditch effort to treat patients with end stage leukaemia. Through the efforts of a large number of laboratory and clinical scientists, the application of transplantation has broadened and outcomes have dramatically improved. The science of transplantation continues to attract a great deal of research, and with this effort we can expect continued progress and patient benefit.
Appelbaum
F R
FR
Clinical Research Division, Fred Hutchinson Cancer Research Center and University of Washington Medical Center, Seattle, Washington 98109-1024, USA. fappelba@fhcrc.org
D000208:Acute Disease; D016026:Bone Marrow Transplantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007938:Leukemia / Q000235:genetics / Q000601:surgery*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000601:surgery; D007951:Leukemia, Myeloid / Q000601:surgery; D011110:Polymorphism, Genetic; D016896:Treatment Outcome
D007166:Immunosuppressive Agents