Wnt pathway activation: new relations and locations.
Recent advances in the Wnt signaling field reveal new components, such as a G protein and an atypical receptor tyrosine kinase, and novel connections between known components. In addition, different subcellular localization of receptors may help to explain distinctions between canonical and noncanonical Wnt pathway activity.
Bejsovec
Amy
A
Department of Biology, Duke University, Durham, NC 27708, USA. bejsovec@duke.edu
D000818:Animals; D019204:GTP-Binding Proteins / Q000378:metabolism; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism*; D008954:Models, Biological; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology*; D051153:Wnt Proteins
D036341:Intercellular Signaling Peptides and Proteins; D051153:Wnt Proteins; D011505:Protein-Tyrosine Kinases; D019204:GTP-Binding Proteins