Bifurcation software in Matlab with applications in neuronal modeling.
Many biological phenomena, notably in neuroscience, can be modeled by dynamical systems. We describe a recent improvement of a Matlab software package for dynamical systems with applications to modeling single neurons and all-to-all connected networks of neurons. The new software features consist of an object-oriented approach to bifurcation computations and the partial inclusion of C-code to speed up the computation. As an application, we study the origin of the spiking behaviour of neurons when the equilibrium state is destabilized by an incoming current. We show that Class II behaviour, i.e. firing with a finite frequency, is possible even if the destabilization occurs through a saddle-node bifurcation. Furthermore, we show that synchronization of an all-to-all connected network of such neurons with only excitatory connections is also possible in this case.
Govaerts
Willy
W
Department of Applied Mathematics and Computer Science, Ghent University, Krijgslaan 281-S9, B-9000 Ghent, Belgium. willy.govaerts@ugent.be
Sautois
Bart
B
D001530:Belgium; D006801:Humans; D008954:Models, Biological; D016571:Neural Networks, Computer; D012985:Software Design