Effect of wavelength on low-intensity laser irradiation-stimulated cell proliferation in vitro.
OBJECTIVE
There exist contradictory reports about low-intensity laser light-stimulated cell proliferation. The purpose of this study was to determine the effect of wavelength on proliferation of cultured murine cells.


METHODS
Proliferation of primary cell cultures was measured after irradiation with varying laser wavelengths.


RESULTS
Fibroblasts proliferated faster than endothelial cells in response to laser irradiation. Maximum cell proliferation occurred with 665 and 675 nm light, whereas 810 nm light was inhibitory to fibroblasts.


CONCLUSIONS
These observations suggest that both wavelength and cell type influence the cell proliferation response to low-intensity laser irradiation.
Moore
Pete
P
University of Oklahoma College of Dentistry, Oklahoma City, Oklahoma 73104, USA.
Ridgway
Tisha D
TD
Higbee
Russell G
RG
Howard
Eric W
EW
Lucroy
Michael D
MD
D000818:Animals; D018929:Cell Culture Techniques; D049109:Cell Proliferation / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D042783:Endothelial Cells / Q000502:physiology / Q000528:radiation effects*; D005347:Fibroblasts / Q000502:physiology / Q000528:radiation effects*; D028022:Low-Level Light Therapy; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H