Detection of stages of autoimmune hemolytic anemia by evaluating erythrocyte deformability and density.
Study of erythrocyte density and deformability in patients with hemolytic anemia, including long-term monitoring of 5 patients, helped us to characterize the pathological processes leading to changes in the erythrocyte population at different terms of the disease and to detect its main stages (agglutination, pathological dehydration, combination of pathological dehydration and microvesiculation, hemolytic crisis, and remission).
Shurkhina
E S
ES
Hematological Research Center, Russian Academy of Medical Sciences, Moscow, Russia.
Nesterenko
V M
VM
Lisovskaya
I L
IL
Tsvetaeva
N V
NV
Kolodei
S V
SV
Nikulina
O F
OF
Ataullakhanov
F I
FI
D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis* / Q000473:pathology; D002452:Cell Count; D004912:Erythrocytes / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male