Two cases of hyperkalemia after administration of hypertonic mannitol during craniotomy.
Mannitol is used commonly as an osmotic diuretic to reduce intracranial pressure during the perioperative period of craniotomy. The rapid administration of mannitol solution can cause an imbalance of electrolytes such as sodium and potassium. Here, we report two cases of mannitol-induced hyperkalemia. We demonstrate that administration of mannitol during craniotomy increases potassium iron concentration, and in some cases it may cause disturbance of cardiac function.
Hirota
Kiichi
K
Department of Anesthesia, The Tazuke Kofukai Medical Research Institute Kitano Hospital, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.
Hara
Tomoko
T
Hosoi
Satoshi
S
Sasaki
Yukiko
Y
Hara
Yasufumi
Y
Adachi
Takehiko
T
D000328:Adult; D000368:Aged; D000758:Anesthesia; D001784:Blood Gas Analysis; D020202:Cerebral Hemorrhage, Traumatic / Q000601:surgery; D003399:Craniotomy; D004232:Diuretics / Q000009:adverse effects*; D004562:Electrocardiography; D006801:Humans; D006947:Hyperkalemia / Q000097:blood / Q000139:chemically induced*; D006982:Hypertonic Solutions; D002532:Intracranial Aneurysm / Q000601:surgery; D007431:Intraoperative Complications / Q000097:blood / Q000139:chemically induced*; D007501:Iron / Q000097:blood; D008297:Male; D008353:Mannitol / Q000009:adverse effects*; D011188:Potassium / Q000097:blood; D013345:Subarachnoid Hemorrhage / Q000601:surgery; D014883:Water-Electrolyte Imbalance / Q000139:chemically induced
D004232:Diuretics; D006982:Hypertonic Solutions; D008353:Mannitol; D007501:Iron; D011188:Potassium