Furocoumarin glycosides from the leaves of Ficus ruficaulis Merr. var. antaoensis.
From the methanolic extract of the leaves of Ficus ruficaulis Merr. var. antaoensis, 5-O-beta-D-glucopyranosyl-6-hydroxyangelicin (1), 6-O-beta-D-glucopyranosyl-5-hydroxyangelicin (2), 5,6-O-beta-D-diglucopyranosylangelicin (3), 8-O-beta-D-glucopyranosyl-5-hydroxypsoralen (4), 5-O-beta-D-glucopyranosyl-8-hydroxypsoralen (5), 3,4,5-trihydroxydehydro-alpha-ionol-9-O-beta-D-glucopyranoside (6), rutin (7), and isoquercitrin (8) were isolated. The structures of compounds 1-4 were elucidated by the analysis of their spectroscopic data. Their in vitro antiproliferation activities were also evaluated.
Chang
Mau-Sun
MS
Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan 251, Republic of China.
Yang
Yuh-Cheng
YC
Kuo
Yuh-Chi
YC
Kuo
Yueh-Hsiung
YH
Chang
Chen
C
Chen
Chin-Mei
CM
Lee
Tzong-Huei
TH
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D030681:Ficus / Q000737:chemistry*; D011564:Furocoumarins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D020128:Inhibitory Concentration 50; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012431:Rutin / Q000737:chemistry; D013237:Stereoisomerism; D013624:Taiwan
D000972:Antineoplastic Agents, Phytogenic; D011564:Furocoumarins; D006027:Glycosides; D012431:Rutin