Two diterpenes and three diterpene glucosides from Phlogacanthus curviflorus.
Two new diterpene lactones, phlogacantholides B (1) and C (2), and three new diterpene lactone glucosides, phlogacanthosides A (3), B (4), and C (5), together with lupeol, beta-sitosterol, betulin, beta-daucosterol, (+)-syringaresinol, and (+)-syringaresinol-4-O-beta-D-glucopyranoside, were isolated from the roots of Phlogacanthus curviflorus. Their structures were elucidated by chemical and spectroscopic evidence. The structure, including the relative configuration of phlogacantholide B (1), was confirmed by X-ray crystallographic analysis of its diacetate (6).
Yuan
Xiao-Hong
XH
Chengdu Institute of Biology, The Chinese Academy of Sciences, Chengdu 610041, People's Republic of China.
Li
Bo-Gang
BG
Zhang
Xiu-Yun
XY
Qi
Hua-Yi
HY
Zhou
Min
M
Zhang
Guo-Lin
GL
D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*
D004224:Diterpenes; D004365:Drugs, Chinese Herbal; D005960:Glucosides