Getting to know your neighbours; a new mechanism for cell intercalation.
As an embryo gastrulates or makes neural tissue it shortens across the dorso-ventral axis and extends dramatically along the perpendicular, antero-posterior axis, resulting in the embryo doubling in length. This process is known as convergent extension and it is so powerful in remodelling tissue that it is used time and again during development. New research in Drosophila melanogaster and other model organisms is shedding fresh light on how it happens.
Nikolaidou
Kelly K
KK
Ludwig Institute for Cancer Research, 91 Riding House Street, London W1W 7BS, UK.
Barrett
Kathy
K
D000818:Animals; D019521:Body Patterning; D002450:Cell Communication; D029721:Drosophila Proteins / Q000378:metabolism; D004331:Drosophila melanogaster; D004625:Embryo, Nonmammalian; D005775:Gastrula / Q000502:physiology; D018507:Gene Expression Regulation, Developmental; D008565:Membrane Proteins / Q000378:metabolism; D008954:Models, Biological; D024462:Myosin Type II / Q000737:chemistry; D009474:Neurons / Q000378:metabolism; D015398:Signal Transduction
D029721:Drosophila Proteins; D008565:Membrane Proteins; C081481:Rho protein, Drosophila; D024462:Myosin Type II