title: High-grade pelvic osteosarcoma with intravascular extension to the right side of the heart: a case report and review of the literature.
abstract: We describe a rare case of high-grade osteosarcoma with intravascular extension to the right atrium and right ventricle in a 23-year-old woman. Osteosarcomas rarely metastasize to the heart, and only a few cases have been reported in the literature thus far. Diagnoses in some of these cases were made during investigation for severe cardiac failure and in most of these cases at autopsy. We describe a unique case of intravascular extension of the tumor embolus in a cordlike fashion from the left femoral vein to the right side of the heart that morphologically resembled a chondrosarcoma.
authors.affiliation: Department of Pathology, University of Illinois at Chicago, 60612, USA. jjani@uic.edu <jjani@uic.edu>
authors.forename: Jigna C
authors.initials: JC
authors.lastname: Jani
authors.forename: Malek
authors.initials: M
authors.lastname: Massad
authors.forename: Jacques
authors.initials: J
authors.lastname: Kpodonu
authors.forename: Victoria
authors.initials: V
authors.lastname: Alagiozian-Angelova
authors.forename: Grace
authors.initials: G
authors.lastname: Guzman
mesh_terms: D000328:Adult; D005260:Female; D006325:Heart Atria / Q000473:pathology*; D006338:Heart Neoplasms / Q000556:secondary*; D006801:Humans; D012516:Osteosarcoma / Q000175:diagnosis* / Q000556:secondary*; D010386:Pelvic Neoplasms / Q000175:diagnosis* / Q000473:pathology; D019043:Vascular Neoplasms / Q000556:secondary*