Antibiotics in the chemical communication of fungi.
In dual cultures Oudemansiella mucida and Xerula melanotricha (basidiomycetes) react to the presence of living Penicillium notatum or P. turbatum with an increased production of strobilurin A (1) or X (2). P. notatum in turn reacts to the two basidiomycetes or their antibiotic strobilurin A alone with the production of N-(2-hydroxypropanoyl)-2-aminobenzoic acid amide (3) or chrysogine (4). P. melinii and P. urticae overgrow O. mucida due to complete resistance to strobilurin A. P. brevicompactum, P. citrinum, P. janczewskii and the other Penicillium strains are all sensitive but apparently do not induce O. mucida to produce the amounts of strobilurin A needed to inhibit their growth.
Kettering
Melanie
M
Institut für Biotechnologie und Wirkstoff-Forschung IBWF e.V., Erwin-Schrödinger-Strasse 56, D-67663 Kaiserslautern, Germany.
Sterner
Olov
O
Anke
Timm
T
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D001487:Basidiomycota / Q000187:drug effects / Q000502:physiology*; D002450:Cell Communication / Q000187:drug effects / Q000502:physiology*; D002851:Chromatography, High Pressure Liquid; D005231:Fatty Acids, Unsaturated / Q000302:isolation & purification / Q000378:metabolism*; D005658:Fungi / Q000187:drug effects / Q000502:physiology*; D009682:Magnetic Resonance Spectroscopy; D008689:Methacrylates; D010407:Penicillium / Q000502:physiology*; D010408:Penicillium chrysogenum / Q000502:physiology*; D011799:Quinazolines / Q000302:isolation & purification / Q000378:metabolism*; D052999:Quinazolinones; D000073739:Strobilurins
D000900:Anti-Bacterial Agents; D005231:Fatty Acids, Unsaturated; D008689:Methacrylates; D011799:Quinazolines; D052999:Quinazolinones; D000073739:Strobilurins; C008556:mucidin; C005537:chrysogine