The role of growth hormone replacement in a growth hormone deficient patient with underlying cardiomyopathy and severe congestive heart failure.
It has been reported that growth hormone (GH) deficiency induced cardiomyopathy responds to growth hormone replacement therapy. We describe the case of a middle-aged male with cardiomyopathic heart failure and growth hormone deficiency of the adult secondary to surgical panhypopituitarism. We demonstrate clinical and hemodynamic improvement of cardiac function with growth hormone replacement therapy despite underlying structural heart disease.
Meyers
Deborah E
DE
Division of Heart Failure and Transplantation, The Prince Charles Hospital, Chermside, Queensland 4032, Australia. deborah_meyers@health.qld.gov.au
Maddicks-Law
Jo
J
Seaton
David M
DM
Galbraith
Andrew J
AJ
Cuneo
Ross C
RC
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood; D002227:Carbazoles / Q000627:therapeutic use; D009202:Cardiomyopathies / Q000188:drug therapy* / Q000503:physiopathology; D000077261:Carvedilol; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D019382:Human Growth Hormone / Q000172:deficiency* / Q000627:therapeutic use*; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000187:drug effects / Q000378:metabolism; D008297:Male; D011412:Propanolamines / Q000627:therapeutic use; D011669:Pulmonary Wedge Pressure / Q000502:physiology; D013318:Stroke Volume / Q000502:physiology; D014655:Vascular Resistance / Q000502:physiology; D018754:Ventricular Dysfunction / Q000188:drug therapy / Q000503:physiopathology
D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D015415:Biomarkers; D002227:Carbazoles; D011412:Propanolamines; D000077261:Carvedilol; D019382:Human Growth Hormone; D007334:Insulin-Like Growth Factor I