[Review of double-blind studies comparing SSRI and SNRI].
In Japan, therapies for depression using serotonin-selective reuptake inhibitors and serotonin noradrenaline reuptake inhibitors have been established for several years. Clinicians seem to differentiate between these and classical antidepressants, i.e., tricyclic and tetracyclic antidepressants. However, it appears to be difficult for most Japanese clinicians to choose the medication most suitable for an individual patient. Herein, we reviewed double-blind studies comparing a serotonin-selective reuptake inhibitor and a serotonin noradrenaline reuptake inhibitor. As yet, we cannot draw a conclusion due to the small data set and methodological discordance among the investigations.
Suzuki
Eiji
E
Department of Psychiatry, Kitasato University School of Medicine.
Maruta
Shuji
S
D018759:Adrenergic Uptake Inhibitors / Q000627:therapeutic use*; D000928:Antidepressive Agents / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D016666:Fluvoxamine / Q000627:therapeutic use; D006801:Humans; D008297:Male; D016032:Randomized Controlled Trials as Topic; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*
D018759:Adrenergic Uptake Inhibitors; D000928:Antidepressive Agents; D016666:Fluvoxamine; D017367:Selective Serotonin Reuptake Inhibitors