Is oral tolerance correlated with IgE levels and mast cell numbers?
A triple genetic association between serum IgE levels, mast cell numbers, and susceptibility to oral tolerance was observed in mice genetically selected to extreme phenotypes of oral tolerance (susceptibility and resistance), suggesting a coadaptation of genes controlling these traits.
da Silva
Antonio Carlos
AC
Laboratório de Imunobiologia, Departamento Biologia Celular e Genética, Instituto de Biologia, UERJ, Rua S. Francisco Xavier, 524, PHLC, Maracanã, Rio de Janeiro, RJ, Brasil, CEP 20.559-900. dasilva@uerj.br
Silva
Maria F S
MF
Bianchi
Cristina
C
Ribeiro
Ricardo C
RC
Nóbrega
Alberto
A
Sant'anna
Osvaldo
O
D000818:Animals; D005753:Gastric Mucosa / Q000276:immunology*; D018928:Immunity, Mucosal; D007073:Immunoglobulin E / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000276:immunology*; D008407:Mast Cells / Q000276:immunology*; D051379:Mice
D007073:Immunoglobulin E