title: ProfDist: a tool for the construction of large phylogenetic trees based on profile distances.
abstract: CONCLUSIONS
  ProfDist is a user-friendly software package using the profile-neighbor-joining method (PNJ) in inferring phylogenies based on profile distances on DNA or RNA sequences. It is a tool for reconstructing and visualizing large phylogenetic trees providing new and standard features with a special focus on time efficency, robustness and accuracy.
  
  
  BACKGROUND
  A Windows version of ProfDist comes with a graphical user interface and is freely available at http://profdist.bioapps.biozentrum.uni-wuerzburg.de
authors.affiliation: Department of Bioinformatics, Biocenter, University of Würzburg, Germany.
authors.forename: Joachim
authors.initials: J
authors.lastname: Friedrich
authors.forename: Thomas
authors.initials: T
authors.lastname: Dandekar
authors.forename: Matthias
authors.initials: M
authors.lastname: Wolf
authors.forename: Tobias
authors.initials: T
authors.lastname: Müller
mesh_terms: D000465:Algorithms; D002874:Chromosome Mapping / Q000379:methods*; D004252:DNA Mutational Analysis / Q000379:methods; D020869:Gene Expression Profiling / Q000379:methods*; D015810:Linkage Disequilibrium / Q000235:genetics*; D010802:Phylogeny; D016415:Sequence Alignment / Q000379:methods; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D014584:User-Computer Interface