title: Topographic distribution of focal left atrial tachycardias defined by electrocardiographic and electrophysiological data.
abstract: BACKGROUND
  Detailed information about the topographic distribution of focal left atrial tachycardias (FLATs) is limited.
  
  
  RESULTS
  A total of 143 atrial tachycardia (AT) foci were successfully ablated in 140 patients (56 men, mean age 44.6+/-17.9 years). In 36.4% (52/143 ATs), a left atrial (LA) origin of the tachycardia was identified from the site of successful ablation. In 46% (24/52) of FLATs, the site of origin (SO) was near the ostium of a pulmonary vein (PV), and in 36.5% (19/52), the SO was near the mitral annulus (MA). In the remaining ATs, the SO was in the left atrial appendage (LAA), septum, LA roof and inside the coronary sinus. P waves in V1 showed biphasic morphology with an initial negative component in most FLATs originating from the septal MA, superior MA, and LAA. However, P waves in V1 were positive in all patients with FLATs originating from PVs. Negative P waves in aVL were always observed in FLATs originating from left PVs. The mean cycle length of FLATs from PVs was significantly shorter than that from the MA.
  
  
  CONCLUSIONS
  Knowledge of the topographic distribution, P-wave morphology, and tachycardia cycle length facilitates successful ablation of FLATs.
authors.affiliation: II. Med. Abteilung (Kardiologie), Allgemeines Krankenhaus St Georg, Hamburg, Germany.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Hachiya
authors.forename: Sabine
authors.initials: S
authors.lastname: Ernst
authors.forename: Feifan
authors.initials: F
authors.lastname: Ouyang
authors.forename: Hercules
authors.initials: H
authors.lastname: Mavrakis
authors.forename: Julian
authors.initials: J
authors.lastname: Chun
authors.forename: Dietmar
authors.initials: D
authors.lastname: Bänsch
authors.forename: Matthias
authors.initials: M
authors.lastname: Antz
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Kuck
mesh_terms: D000328:Adult; D020517:Atrial Appendage / Q000503:physiopathology; D018780:Body Surface Potential Mapping; D017115:Catheter Ablation; D004562:Electrocardiography; D022062:Electrophysiologic Techniques, Cardiac; D005260:Female; D006325:Heart Atria / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013612:Tachycardia, Ectopic Atrial / Q000175:diagnosis* / Q000628:therapy