title: Improvement of liver function after surgery for Budd-Chiari syndrome.
abstract: OBJECTIVE
  We evaluated the relationship between liver histology and postoperative improvement of liver function after surgery for Budd-Chiari syndrome (BCS).
  
  
  METHODS
  Over a period of 23 years, we operated on 46 patients with BCS by reconstructing the occluded inferior vena cava (IVC) and reopening as many occluded hepatic veins as possible. We divided the patients into a liver cirrhosis group (group I, n = 30) and a hepatic fibrosis or liver congestion group (group II, n = 16), and compared the ages, duration of illness, preoperative liver function, changes in liver function, and changes in esophageal varices (EV).
  
  
  RESULTS
  There were no hospital deaths. In group I the patients were older, and the duration of illness was longer. The group I patients also had a lower thrombotest percentage and a higher serum ammonia. The indocyanine green clearance (ICG) test showed more remarkable improvement in liver function in group II. The rate of disappearance of EV was also higher in group II.
  
  
  CONCLUSIONS
  Surgery during the early stage of BCS is important in improving postoperative liver function.
authors.affiliation: Department of Bioregulatory Medicine, Thoracic and Cardiovascular Surgery Division, University of the Ryukyus, 207 Uehara, Nishihara-cho, Okinawa 903-0215, Japan.
authors.forename: Yukio
authors.initials: Y
authors.lastname: Kuniyoshi
authors.forename: Kageharu
authors.initials: K
authors.lastname: Koja
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Miyagi
authors.forename: Tooru
authors.initials: T
authors.lastname: Uezu
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yamashiro
authors.forename: Katsuya
authors.initials: K
authors.lastname: Arakaki
authors.forename: Takaaki
authors.initials: T
authors.lastname: Nagano
authors.forename: Katsuhito
authors.initials: K
authors.lastname: Mabuni
authors.forename: Shigenobu
authors.initials: S
authors.lastname: Senaha
mesh_terms: D000328:Adult; D006502:Budd-Chiari Syndrome / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D004932:Esophageal and Gastric Varices / Q000150:complications; D005260:Female; D006801:Humans; D008099:Liver / Q000503:physiopathology*; D008103:Liver Cirrhosis / Q000150:complications; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D013997:Time Factors