title: Binding of S-citalopram and paroxetine discriminates between species.
authors.affiliation: Laboratory of Molecular Neurobiology, Department of Biological Psychiatry, Aarhus Psychiatric University Hospital, Risskov, Denmark. belfving@tiscali.dk
authors.forename: Betina
authors.initials: B
authors.lastname: Elfving
authors.forename: Ove
authors.initials: O
authors.lastname: Wiborg
mesh_terms: D000818:Animals; D001596:Benzylamines / Q000378:metabolism / Q000494:pharmacology; D001667:Binding, Competitive / Q000187:drug effects* / Q000502:physiology; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D002478:Cells, Cultured; D002645:Chickens; D015283:Citalopram / Q000378:metabolism* / Q000493:pharmacokinetics / Q000494:pharmacology; D019143:Evolution, Molecular; D006801:Humans; D007546:Isoquinolines / Q000378:metabolism / Q000494:pharmacology; D008024:Ligands; D008562:Membrane Glycoproteins / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism; D026901:Membrane Transport Proteins / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism; D017374:Paroxetine / Q000378:metabolism* / Q000493:pharmacokinetics / Q000494:pharmacology; D011869:Radioligand Assay; D051381:Rats; D012701:Serotonin / Q000378:metabolism; D012702:Serotonin Antagonists / Q000378:metabolism / Q000494:pharmacology; D050486:Serotonin Plasma Membrane Transport Proteins; D017367:Selective Serotonin Reuptake Inhibitors / Q000378:metabolism* / Q000493:pharmacokinetics / Q000494:pharmacology; D020280:Sertraline / Q000378:metabolism / Q000494:pharmacology; D013045:Species Specificity; D014316:Tritium
chemical_list: D001596:Benzylamines; D015283:Citalopram; D007546:Isoquinolines; D008024:Ligands; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; D017374:Paroxetine; D012701:Serotonin; D012702:Serotonin Antagonists; D050486:Serotonin Plasma Membrane Transport Proteins; D017367:Selective Serotonin Reuptake Inhibitors; D020280:Sertraline; D014316:Tritium; C470437:N,N-dimethyl-2-(2-amino-4-methylphenylthio)benzylamine; C493230:SLC6A4 protein, human; C493232:Slc6a4 protein, rat; C058079:McN 5652