title: [Study of saccadic eye movement in children with attention deficit/hyperactivity disorder].
abstract: Recent studies have postulated that impairment of behavior inhibition, leading to executive dysfunction in future, is the fundamental pathophysiology of attention deficit/hyperactivity disorder (AD/HD). To evaluate this, we studied two saccadic eye movement tasks: visual- and memory-guided, in 8 children with AD/HD (combined type;mean age, 9.1 years, range 6 approximately 11 years) and 16 healthy children (mean age, 9.2 years, range 6 approximately 12 years). In the memory-guided saccade task, reflexive anticipatory errors were more frequently observed in AD/HD than in controls. The children with AD/HD showed longer response latency in the memory-guided saccade task, and greater coefficient of variation in both the latency and amplitude in both the tasks. These results suggested that saccade tasks, especially the memory-guided task, may be useful in clarifying pathophysiology of AD/HD.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, University of Yamanashi, Nakakoma, Yamanashi.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Goto
authors.forename: Masao
authors.initials: M
authors.lastname: Aihara
authors.forename: Kazuo
authors.initials: K
authors.lastname: Hatakeyama
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Kitama
authors.forename: Yu
authors.initials: Y
authors.lastname: Sato
authors.forename: Shinpei
authors.initials: S
authors.lastname: Nakazawa
mesh_terms: D001289:Attention Deficit Disorder with Hyperactivity / Q000145:classification / Q000503:physiopathology*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D011597:Psychomotor Performance; D011930:Reaction Time / Q000502:physiology; D012438:Saccades / Q000502:physiology*