title: Tramadol overdose and serotonin syndrome manifesting as acute right heart dysfunction.
abstract: Acute right heart failure in a young person is an unusual presentation and drug overdose is a rare cause. A case is described where the patient presented with striking clinical signs of acute pulmonary hypertension and right heart failure, which were confirmed by transthoracic echocardiography. The precipitating event appeared to be poisoning by tramadol. There were features in keeping with tramadol toxicity and serotonin syndrome. The possible pathophysiology behind the process is discussed.
authors.affiliation: Emergency and Intensive Care Department, The Tweed Hospital, New South Wales.
authors.forename: P M
authors.initials: PM
authors.lastname: Garrett
mesh_terms: D000208:Acute Disease; D000328:Adult; D000701:Analgesics, Opioid / Q000506:poisoning*; D062787:Drug Overdose; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000139:chemically induced* / Q000175:diagnosis; D012206:Rhabdomyolysis / Q000139:chemically induced; D020230:Serotonin Syndrome / Q000175:diagnosis* / Q000209:etiology; D014147:Tramadol / Q000506:poisoning*; D018497:Ventricular Dysfunction, Right / Q000139:chemically induced*
chemical_list: D000701:Analgesics, Opioid; D014147:Tramadol