title: Narrative review: pharmacotherapy for chronic heart failure: evidence from recent clinical trials.
abstract: Heart failure is an important cause of morbidity and mortality. Clinical trials over the past 2 decades have revolutionized the care of patients with systolic heart failure, and substantial data support the use of angiotensin-converting enzyme inhibitors, beta-blockers, angiotensin-receptor blockers, and aldosterone blockers in the management of this serious condition. This article reviews the evidence on the pharmacologic treatment of heart failure, with a focus on recent clinical trials.
authors.affiliation: St. Michael's Hospital, the Heart & Stroke/Richard Lewar Centre of Excellence, and Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
authors.forename: Andrew T
authors.initials: AT
authors.lastname: Yan
authors.forename: Raymond T
authors.initials: RT
authors.lastname: Yan
authors.forename: Peter P
authors.initials: PP
authors.lastname: Liu
mesh_terms: D002317:Cardiovascular Agents / Q000627:therapeutic use*; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D016032:Randomized Controlled Trials as Topic
chemical_list: D002317:Cardiovascular Agents