title: Moderate to severe obstructive sleep apnoea patients is associated with a higher incidence of visual field defect.
abstract: OBJECTIVE
  To compare the visual fields (VFs) and optic nerve head changes between obstructive sleep apnoea (OSA) in normotensive patients and an age-matched non-OSA population.
  
  
  METHODS
  Case-control study.
  
  
  METHODS
  A total of 41 ethnic Chinese patients diagnosed with moderate to severe OSA referred from the Sleep Laboratory, ENT Department, Tuen Mun Hospital. A total of 35 age-matched non-OSA subjects recruited from the Ophthalmology Department, North District Hospital.
  
  
  METHODS
  Comprehensive ophthalmological and systemic history, complete ophthalmological examination, including central-30 computerized perimetry for all studied patients.
  
  
  METHODS
  Polysomnographic data, VF indices, optic disc changes.
  
  
  RESULTS
  In the OSA arm, VF indices were significantly subnormal and the incidence of suspicious glaucomatous disc changes was four times higher than that of the control arm. None of the studied patients suffered from any form of anterior segment complications.
  
  
  CONCLUSIONS
  Moderate to severe OSA is associated with a higher incidence of VF defect and glaucomatous optic nerve changes.
authors.affiliation: Department of Ophthalmology, Tuen Mun Hospital, Hong Kong SAR, China. colette_tsg@hotmail.com
authors.forename: C S L
authors.initials: CS
authors.lastname: Tsang
authors.forename: S L
authors.initials: SL
authors.lastname: Chong
authors.forename: C K
authors.initials: CK
authors.lastname: Ho
authors.forename: M F
authors.initials: MF
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005260:Female; D005901:Glaucoma / Q000209:etiology / Q000473:pathology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology; D017286:Polysomnography; D012607:Scotoma / Q000209:etiology* / Q000473:pathology; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000473:pathology; D058609:Visual Field Tests; D014794:Visual Fields