[Predictive value of glycemia in acute coronary syndromes].
Intravenous insulin therapy is used in diabetic patients at the acute phase of coronary syndrome (ACS). However, hyperglycemia in diabetic patients is a powerful predictive factor for patient outcome as it is associated with a doubling of in-hospital mortality and poor long-term prognosis. Recent studies involving non-diabetic patients show that even mild hyperglycemia in the setting of ACS is also a predictive factor of in-hospital mortality. Moreover, the new entity called impaired fasting glucose (IFG) (6.1 to 7 mmol/L) is not only an independent factor of mortality for coronary patients, but very recently has also been associated with a doubling of the risk of in-hospital mortality in the setting of ACS. Admission as well as follow-up glycaemia are fundamental parameters in ACS on the one hand for their prognostic value, and on the other end as a diagnostic tool in determining the presence of diabetes or IFG.
Rioufol
G
G
Observatoire des infarctus de la Côte-d'Or, laboratoire de physiopathologie et pharmacologie cardiovasculaires expérimentales, faculté de médecine, Dijon.
Zeller
M
M
Oudot
A
A
L'Huillier
I
I
Buffet
P
P
Beer
J C
JC
Verges
B
B
Wolf
J E
JE
Rochette
L
L
Cottin
Y
Y
D000208:Acute Disease; D000789:Angina, Unstable / Q000097:blood / Q000175:diagnosis*; D001786:Blood Glucose; D006801:Humans; D009203:Myocardial Infarction / Q000097:blood* / Q000175:diagnosis*; D011237:Predictive Value of Tests; D013577:Syndrome
D001786:Blood Glucose