Cardiac wall motion abnormalities observed in a patient with transient hyperthyroidism.
A 74-year-old woman, with a history of hypertension and hyperlipidemia, was admitted to our hospital. She was found to have a sinus tachycardia with ST-segment elevations in leads II, III, (a)V(F), and V(3) through V(6) in electrocardiography, hypokinesis of the left ventricular apex by echocardiography, and normal findings on coronary angiography. Blood analysis revealed an increase in the creatine kinase MB fraction, a significant positive detection in troponin T, and transient elevations in the concentrations of free triiodothyronine, free thyroxine, thyroid globulin antibody, and thyroid peroxidase antibody. Defects in myocardial perfusion and fatty acid metabolism in the apical area were also demonstrated by myocardial scintigraphy. These data suggest that tako-tsubo syndrome or myocardial infarction may be induced in patients with mild and transient hyperthyroidism.
Sakaki
Takatoshi
T
Department of Internal Medicine, Division of Coronary Heart Disease, Hyogo College of Medicine, Japan.
Fujioka
Yoshio
Y
Akagami
Takafumi
T
Masai
Miho
M
Shimizu
Hiroshi
H
Sakoda
Tsuyoshi
T
Tsujino
Takeshi
T
Ohyanagi
Mitsumasa
M
D000368:Aged; D001281:Atrial Fibrillation / Q000175:diagnosis; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications; D006973:Hypertension / Q000150:complications; D006980:Hyperthyroidism / Q000150:complications / Q000503:physiopathology*; D009200:Myocardial Contraction; D009203:Myocardial Infarction / Q000150:complications; D013616:Tachycardia, Sinus / Q000175:diagnosis; D018487:Ventricular Dysfunction, Left / Q000150:complications