Antimicrobial activity and chemical investigation of Brazilian Drosera.
The antimicrobial activity of three different extracts (hexanic, ethyl acetate, methanol) obtained from Brazilian Drosera species (D. communis, D. montana var. montana, D. brevifolia, D. villosa var. graomogolensis, D. villosa var. villosa, Drosera sp. 1, and Drosera sp. 2 ) were tested against Staphylococcus aureus (ATCC 25923), Enterococcus faecium (ATCC23212), Pseudomonas aeruginosa (ATCC27853), Escherichia coli (ATCC11229), Salmonella choleraesuis (ATCC10708), Klebsiella pneumoniae (ATCC13883), and Candida albicans (a human isolate). Better antimicrobial activity was observed with D. communis and D. montana var. montana ethyl acetate extracts. Phytochemical analyses from D. communis, D. montana var. montana and D. brevifolia yielded 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin); long chain aliphatic hydrocarbons were isolated from D. communis and from D. villosa var. villosa, a mixture of long chain aliphatic alcohols and carboxylic acids, was isolated from D. communis and 3b-O-acetylaleuritolic acid from D. villosa var. villosa.
Ferreira
Dalva Trevisan
DT
Departamento de Química, Centro de Ciências Exatas, Universidade Estadual de Londrina, Caixa Postal 6001, 86051-970 Londrina, PR, Brazil. dalva@uel.br
Andrei
César Cornélio
CC
Saridakis
Halha Ostrensky
HO
Faria
Terezinha de Jesus
Tde J
Vinhato
Elisângela
E
Carvalho
Kátia Eliane
KE
Daniel
Juliana Feijó Souza
JF
Machado
Sílvio Luiz
SL
Saridakis
Dennis Panayotis
DP
Braz-Filho
Raimundo
R
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects; D029787:Drosera / Q000737:chemistry*; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D010936:Plant Extracts