title: Test characteristics of perirectal and rectal swab compared to stool sample for detection of fluoroquinolone-resistant Escherichia coli in the gastrointestinal tract.
abstract: Among 63 patients enrolled in a prospective cohort study of gut colonization with fluoroquinolone-resistant Escherichia coli, the sensitivity of perirectal swab compared to stool sample was 90% (95% confidence interval [CI], 70 to 99%) and the specificity was 100% (95% CI, 91 to 100%). For rectal swab, the sensitivity was 90% (95% CI, 68 to 99%) and the specificity was 100% (95% CI, 91 to 100%).
authors.affiliation: Division of Infectious Diseases, Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6021, USA. elautenb@cceb.med.upenn.edu
authors.forename: Ebbing
authors.initials: E
authors.lastname: Lautenbach
authors.forename: Anthony D
authors.initials: AD
authors.lastname: Harris
authors.forename: Eli N
authors.initials: EN
authors.lastname: Perencevich
authors.forename: Irving
authors.initials: I
authors.lastname: Nachamkin
authors.forename: Pam
authors.initials: P
authors.lastname: Tolomeo
authors.forename: Joshua P
authors.initials: JP
authors.lastname: Metlay
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D004064:Digestive System / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000187:drug effects*; D005243:Feces / Q000382:microbiology*; D005260:Female; D024841:Fluoroquinolones / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012007:Rectum / Q000382:microbiology*; D015203:Reproducibility of Results
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones