title: Malformations of cortical development: high-resolution MR and diffusion tensor imaging of fiber tracts at 3T.
abstract: Patients with malformations of cortical development and epilepsy may have a variety of abnormal brain findings, including abnormal gyral patterns, cortical thickening, decreased volume of white matter, and increased diffusion of white matter. The status of individual white matter fiber tracts, however, is unknown. We present a case of bilateral frontal schizencephaly and subcortical heterotopia and illustrate alterations of white matter fascicles by combined structural and functional diffusion tensor imaging at 3 T.
authors.affiliation: Department of Neuroradiology, National Neuroscience Institute, Singapore.
authors.forename: C C Tchoyoson
authors.initials: CC
authors.lastname: Lim
authors.forename: Hong
authors.initials: H
authors.lastname: Yin
authors.forename: Ngai Kun
authors.initials: NK
authors.lastname: Loh
authors.forename: Violet G E
authors.initials: VG
authors.lastname: Chua
authors.forename: Francis
authors.initials: F
authors.lastname: Hui
authors.forename: A James
authors.initials: AJ
authors.lastname: Barkovich
mesh_terms: D000328:Adult; D061085:Agenesis of Corpus Callosum; D002540:Cerebral Cortex / Q000002:abnormalities* / Q000473:pathology; D002828:Choristoma / Q000175:diagnosis / Q000473:pathology; D003337:Corpus Callosum / Q000473:pathology; D038524:Diffusion Magnetic Resonance Imaging; D004805:Ependyma / Q000002:abnormalities / Q000473:pathology; D004827:Epilepsy / Q000151:congenital* / Q000175:diagnosis; D005625:Frontal Lobe / Q000002:abnormalities / Q000473:pathology; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D008607:Intellectual Disability / Q000175:diagnosis / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D009412:Nerve Fibers / Q000473:pathology; D009434:Neural Pathways / Q000002:abnormalities* / Q000473:pathology; D011712:Pyramidal Tracts / Q000002:abnormalities / Q000473:pathology; D012688:Septum Pellucidum / Q000002:abnormalities