Corneal oxygen deficiency.
OBJECTIVE
To compare the ocular effects of low Dk hydrogel and high Dk silicone hydrogel contact lenses.


METHODS
A review of recent literature was conducted to determine the effects of wearing low and high Dk soft lenses on corneal swelling, vascular response, refractive error and the corneal epithelium.


RESULTS
High Dk silicone hydrogel contact lenses became available for research and clinical practice almost 10 and 5 years ago respectively. During that time many studies have been conducted and it has been demonstrated repeatedly how much improvement there has been to the physiological response of the eye particularly when wearing the lenses on an overnight basis.


CONCLUSIONS
Although silicone hydrogels only constitute about 2% of current wearers, their positive effects on the eye compared with low Dk hydrogel lenses should make them the most dominant lenses in the near future.
Fonn
Desmond
D
Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada. dfonn@sciborg.uwaterloo.ca
Sweeney
Deborah
D
Holden
Brien A
BA
Cavanagh
Dwight
D
D001424:Bacterial Infections / Q000209:etiology; D003261:Contact Lenses / Q000009:adverse effects*; D003315:Cornea / Q000382:microbiology; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D000860:Hypoxia / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D012828:Silicones
D012828:Silicones; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate