title: Editorial overview: safety/toxicity threshold concepts in drug discovery and development.
authors.forename: Dale E
authors.initials: DE
authors.lastname: Johnson
authors.forename: Dennis A
authors.initials: DA
authors.lastname: Smith
authors.forename: B Kevin
authors.initials: BK
authors.lastname: Park
mesh_terms: D000818:Animals; D002273:Carcinogens / Q000633:toxicity; D015195:Drug Design; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D014116:Toxicology
chemical_list: D002273:Carcinogens