title: [Vascular biology of coronary bypass grafts. Literature review].
abstract: Myocardial revascularisation by coronary bypass surgery is the treatment of choice for patients with multivessel disease. The most commonly used grafts are the internal mammary artery and the saphenous vein. Although the use of internal mammery artery grafts gives excellent results, venous grafts, with time, are subject to atheroma which affects their patency. Improved physiopathological understanding of the natural history of grafts, especially the saphenous vein grafts, has opened the field for different operative strategies to try and reduce the incidence of coronary graft disease. This paper reviews the literature concerning the biology of coronary grafts used for myocardial revascularisation and the current and future therapeutic implications of this data.
authors.affiliation: Département de chirurgie cardiaque, Institut cardiologique de Montréal, Québec, Canada. lesbarandon@wanadoo.fr
authors.forename: L
authors.initials: L
authors.lastname: Barandon
authors.forename: M
authors.initials: M
authors.lastname: Kindo
authors.forename: L P
authors.initials: LP
authors.lastname: Perrault
authors.forename: Y
authors.initials: Y
authors.lastname: Hebert
authors.forename: R
authors.initials: R
authors.lastname: Cartier
authors.forename: D
authors.initials: D
authors.lastname: Bouchard
authors.forename: P
authors.initials: P
authors.lastname: Demers
authors.forename: P
authors.initials: P
authors.lastname: Pagé
authors.forename: M
authors.initials: M
authors.lastname: Carrier
authors.forename: M
authors.initials: M
authors.lastname: Pellerin
mesh_terms: D001158:Arteries / Q000637:transplantation; D001026:Coronary Artery Bypass; D006083:Graft Occlusion, Vascular / Q000473:pathology / Q000503:physiopathology / Q000517:prevention & control*; D006801:Humans; D012501:Saphenous Vein / Q000637:transplantation; D014654:Vascular Patency / Q000502:physiology