Pyrenyldiazomethane, a versatile reagent for nucleotide phosphate alkylation.
Pyrenyldiazomethane was shown to react quantitatively and selectively at phosphate with 2'-, 3'-, and 5'-nucleotide phosphates incorporating the different nucleic bases.
Kotera
Mitsuharu
M
LEDSS, UMR5616 CNRS-BP53, Université Joseph Fourier, 38041 Grenoble, France. kotera@bioorga.u-strasbg.fr
Dheu
Marie-Louise
ML
Milet
Anne
A
Lhomme
Jean
J
Laayoun
Ali
A
D000478:Alkylation; D001391:Azo Compounds / Q000737:chemistry; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D015394:Molecular Structure; D009711:Nucleotides / Q000737:chemistry*; D011721:Pyrenes / Q000737:chemistry; D012997:Solvents; D013329:Structure-Activity Relationship; D013696:Temperature
D001391:Azo Compounds; D007202:Indicators and Reagents; D009711:Nucleotides; D011721:Pyrenes; D012997:Solvents; C500878:pyrenyldiazomethane