title: PNP with Waldenström's macroglobulinaemia.
abstract: We describe a 65-year-old Caucasian man with Waldenstrom's macroglobulinaemia who developed paraneoplastic pemphigus (PNP) 3 years after his haematological diagnosis. This is a very rare malignancy that is associated with PNP. The evolution of PNP in this patient appears to exhibit the postulated immunological phenomenon of epitope spreading.
authors.affiliation: Department of Dermatology, King's College Hospital, London, UK. gayathriperera@aol.com
authors.forename: G K
authors.initials: GK
authors.lastname: Perera
authors.forename: S
authors.initials: S
authors.lastname: Devereux
authors.forename: G
authors.initials: G
authors.lastname: Mufti
authors.forename: J
authors.initials: J
authors.lastname: Salisbury
authors.forename: D
authors.initials: D
authors.lastname: Creamer
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D010257:Paraneoplastic Syndromes / Q000139:chemically induced / Q000209:etiology*; D010392:Pemphigus / Q000139:chemically induced / Q000209:etiology*; D012878:Skin Neoplasms / Q000188:drug therapy; D014740:Vidarabine / Q000009:adverse effects* / Q000031:analogs & derivatives*; D008258:Waldenstrom Macroglobulinemia / Q000150:complications* / Q000188:drug therapy
chemical_list: D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D014740:Vidarabine; C024352:fludarabine