title: Widespread and invasive Trichophyton rubrum infection mimicking Kaposi's sarcoma in a patient with AIDS.
abstract: Opportunistic fungal infections are commonly encountered in AIDS patients. Candidiasis, tinea pedis, onychomycosis, and deep mycotic infections have been the fungal infections most frequently reported in these patients. Dermatophyte infections can appear to be atypical and aggressive in these patients and may lead to a misdiagnosis. We report a Trichophyton rubrum infection in a 44-year-old man with AIDS that presented as a widespread and multiple tumor-like appearance. After the patient was treated with terbinafine for 21 weeks, the lesions cleared completely. We think that this type of dermatophyte infection is very unusual in patients with AIDS and could lead to inappropriate diagnostic processes and treatments.
authors.affiliation: Department of Dermatology, College of Medicine, Pusan National University, Busan, Korea.
authors.forename: Kyung-Sool
authors.initials: KS
authors.lastname: Kwon
authors.forename: Ho-Sun
authors.initials: HS
authors.lastname: Jang
authors.forename: Hyo-Sung
authors.initials: HS
authors.lastname: Son
authors.forename: Chang-Keun
authors.initials: CK
authors.lastname: Oh
authors.forename: Yoo-Wook
authors.initials: YW
authors.lastname: Kwon
authors.forename: Ki-Hong
authors.initials: KH
authors.lastname: Kim
authors.forename: Soon-Bong
authors.initials: SB
authors.lastname: Suh
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy; D000328:Adult; D001707:Biopsy, Needle; D003881:Dermatomycoses / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D016469:Fungemia / Q000175:diagnosis*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009281:Naphthalenes / Q000627:therapeutic use; D012307:Risk Factors; D012514:Sarcoma, Kaposi / Q000175:diagnosis / Q000473:pathology*; D012720:Severity of Illness Index; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology*; D000077291:Terbinafine; D014005:Tinea / Q000175:diagnosis*; D016896:Treatment Outcome; D014249:Trichophyton / Q000302:isolation & purification
chemical_list: D009281:Naphthalenes; D000077291:Terbinafine