Glaucoma following penetrating ocular trauma: a cohort study of the United States Eye Injury Registry.
OBJECTIVE
To evaluate associations between baseline structural and functional ocular characteristics and the risk of developing posttraumatic glaucoma after penetrating ocular injury.


METHODS
Prospective cohort study.


METHODS
Data from the United States Eye Injury Registry (USEIR) were obtained from a total of 3,627 patients who experienced penetrating ocular injury. The risk of posttraumatic glaucoma and associated structural and functional ocular risk factors was estimated.


RESULTS
The risk of developing posttraumatic glaucoma was 2.67%. The development of glaucoma was independently associated with several baseline characteristics including advancing age (relative risk 1.02/yr 95% confidence interval [1.00, 1.03]), lens injury (1.56 [1.03, 2.35]), poor baseline visual acuity (2.59 [1.62, 4.14]), and inflammation (3.02 [1.52, 6.02]).


CONCLUSIONS
This study provides an estimate for the risk of developing glaucoma after penetrating ocular injury in a large cohort of patients and determined several factors that are significantly associated with the development of post-traumatic glaucoma, including advancing age, lens injury, poor visual acuity, and intraocular inflammation.
Girkin
Christopher A
CA
Department of Ophthalmology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA. cgirkin@uab.edu
McGwin
Gerald
G
Morris
Robert
R
Kuhn
Ferenc
F
D000328:Adult; D015331:Cohort Studies; D015807:Eye Injuries, Penetrating / Q000150:complications*; D005260:Female; D005901:Glaucoma / Q000453:epidemiology* / Q000209:etiology*; D006801:Humans; D015994:Incidence; D008297:Male; D011446:Prospective Studies; D012042:Registries / Q000706:statistics & numerical data*; D012307:Risk Factors; D014481:United States / Q000453:epidemiology; D014792:Visual Acuity