Effect of corporal fibroids on outcome following embryo transfer in donor-oocyte recipients.
OBJECTIVE
To evaluate the effect of intramural or subserosal fibroids in the uterine fundus or corpus on pregnancy outcome following transfer of embryos formed from donated oocytes methods.


METHODS
Leiomyomata were measured in three dimensions by transvaginal sonography. Scanning was performed in two planes (sagittal and coronal) at the level of maximal width. The location was categorized by depth in the uterus.


RESULTS
There was no difference in pregnancy rates in those with or without fibroids. However, there was a significantly higher miscarriage rate in the former group.


CONCLUSIONS
Women with fibroids are generally older. Thus conclusions about the effect on miscarriage rates are complicated by the effect of the aging oocyte on miscarriages. This study eliminated the oocyte factor by using only younger donated oocytes.
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The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA.
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D000022:Abortion, Spontaneous / Q000453:epidemiology; D000328:Adult; D000367:Age Factors; D016022:Case-Control Studies; D004624:Embryo Transfer; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000628:therapy; D018231:Leiomyomatosis / Q000453:epidemiology*; D009515:New Jersey / Q000453:epidemiology; D018587:Oocyte Donation; D011247:Pregnancy; D018873:Pregnancy Rate; D014594:Uterine Neoplasms / Q000453:epidemiology*