title: [Proinflammatory cytokines in the development of bacterial keratitis].
abstract: The production of proinflammatory cytokines IL-1alpha, IL1 2b, TNF-alpha and IL8 in lachrymal fluid was dynamically determined in 134 patients with uncomplicated and complicated clinical courses of primary (at exacerbation of the cornea) and secondary (with dystrophic changes in the cornea) keratitis. The level of proinflammatory cytokines in lachrymal fluid was found to essentially affect the clinical course in different types of keratitis.
authors.forename: L N
authors.initials: LN
authors.lastname: Tarasova
authors.forename: V A
authors.initials: VA
authors.lastname: Shaimova
authors.forename: A S
authors.initials: AS
authors.lastname: Simbirtsev
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000378:metabolism; D002648:Child; D003315:Cornea / Q000473:pathology; D016207:Cytokines / Q000378:metabolism*; D003937:Diagnosis, Differential; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000378:metabolism*; D005260:Female; D006801:Humans; D007634:Keratitis / Q000175:diagnosis / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D013666:Tears / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D016207:Cytokines