The foveal photoreceptor layer and visual acuity loss in central serous chorioretinopathy.
OBJECTIVE
To describe changes of the foveal photoreceptor layer using optical coherence tomography (OCT) in central serous chorioretinopathy (CSC) and evaluate the correlation with visual acuity (VA) loss.


METHODS
Observational case series.


METHODS
We studied 28 eyes with acute or chronic CSC using high-resolution OCT. The tomographic findings of the detached foveal photoreceptor layer were compared with VA. Sixteen eyes also were evaluated after foveal reattachment.


RESULTS
The outer photoreceptor layer (OPL) in the detached fovea was preserved in 14 eyes, of which 13 had symptoms for <1 year and atrophic in 14 eyes with symptoms for >1 year. The preserved OPL had an even profile in 7 eyes and a granulated profile in 7 eyes. Mean VA was 0.19 logMAR with a preserved OPL and 0.72 logMAR with an atrophic OPL (P <.001). Cases seen after the detachment resolved included 6 eyes with preserved even OPL, 5 eyes with preserved granulated OPL, and 5 eyes with atrophic OPL. Mean final VA was 0.06 logMAR in eyes with preserved OPL and 0.90 logMAR in eyes with atrophic OPL (P <.001). The VA improved in 73% of eyes with preserved OPL and no eyes with atrophic OPL (P = .025). The VA recovered completely in 83% of eyes with preserved even OPL and no eyes with preserved granulated OPL (P = .015).


CONCLUSIONS
High-resolution OCT demonstrates changes in the foveal photoreceptor layer in CSC that highly correlate with VA loss and may predict visual recovery after macular reattachment.
Piccolino
Felice Cardillo
FC
Institute of Ophthalmology, Department of Clinical Physiopathology, University of Torino, Torino, Italy. felice.cardillopiccolino@unito.it
de la Longrais
Roberta Rigault
RR
Ravera
Giambattista
G
Eandi
Chiara M
CM
Ventre
Luca
L
Abdollahi
Ali'
A
Manea
Marilisa
M
D000208:Acute Disease; D000328:Adult; D000368:Aged; D001837:Body Weights and Measures; D002908:Chronic Disease; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D005584:Fovea Centralis / Q000473:pathology*; D006801:Humans; D007208:Indocyanine Green; D017075:Laser Coagulation; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy; D020419:Photoreceptor Cells, Vertebrate / Q000473:pathology*; D011446:Prospective Studies; D012163:Retinal Detachment / Q000175:diagnosis / Q000628:therapy; D012164:Retinal Diseases / Q000175:diagnosis* / Q000628:therapy; D041623:Tomography, Optical Coherence; D014786:Vision Disorders / Q000175:diagnosis*; D014792:Visual Acuity
D004396:Coloring Agents; D007208:Indocyanine Green