title: Nucleoside-based phospholipids and their liposomes formed in water.
abstract: Phospholipids and liposomes have been the subjects of considerable attention because of their importance in biological systems. We have efficiently synthesized novel nucleoside-based phospholipids in six-step sequences starting from their corresponding nucleosides. These nucleoside-based phospholipids self-assemble into liposome-like structures in aqueous solutions. We have analyzed the structures of these liposomes by dynamic light scattering, transmission electron microscopy, and confocal microscopy.
authors.affiliation: Department of Chemistry, Division of Molecular and Life Sciences, Pohang University of Science and Technology, San 31 Hyoja Dong, Pohang 790-784, South Korea.
authors.forename: Seung Kyu
authors.initials: SK
authors.lastname: Choi
authors.forename: Tran Khac
authors.initials: TK
authors.lastname: Vu
authors.forename: Jin Mi
authors.initials: JM
authors.lastname: Jung
authors.forename: Su Jeong
authors.initials: SJ
authors.lastname: Kim
authors.forename: Hun Rok
authors.initials: HR
authors.lastname: Jung
authors.forename: Taihyun
authors.initials: T
authors.lastname: Chang
authors.forename: Byeang Hyean
authors.initials: BH
authors.lastname: Kim
mesh_terms: D016650:Fluorescein-5-isothiocyanate / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D008081:Liposomes / Q000737:chemistry*; D015394:Molecular Structure; D009705:Nucleosides / Q000737:chemistry*; D010743:Phospholipids / Q000138:chemical synthesis / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D008081:Liposomes; D009705:Nucleosides; D010743:Phospholipids; D014867:Water; D016650:Fluorescein-5-isothiocyanate