Clinical role of lipid transfer proteins in food allergy.
Lipid transfer proteins are widespread plant food allergens, highly resistant to food processing and to the gastrointestinal environment, which have recently been described as true food allergens in the Mediterranean area, where they have been associated with severe allergic reactions to foods in patients without pollen allergy. In this review we analyze their molecular structure, biological function, and clinical relevance in food allergy.
Pastorello
Elide A
EA
Complex Unit of Allergology and Clinical Immunology, Niguarda Ca' Granda Hospital, Milan, Italy. elide.pastorello@unimi.it
Robino
Anna M
AM
D052179:Antigens, Plant; D002352:Carrier Proteins / Q000737:chemistry / Q000276:immunology / Q000502:physiology*; D005512:Food Hypersensitivity / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D006801:Humans; D007114:Immunization; D010940:Plant Proteins; D013329:Structure-Activity Relationship
D052179:Antigens, Plant; D002352:Carrier Proteins; D010940:Plant Proteins; C511920:lipid transfer proteins, plant