Botulinum toxin type A in experimental neuropathic pain.
A peripheral application of botulinum toxin type A (7 U/kg) has significantly reduced thermal and mechanical hypersensitivity in rats with the partial sciatic nerve transection as a classical model of surgical neuropathy.
Bach-Rojecky
L
L
Department of Pharmacology, School of Pharmacy and Biochemistry, University of Zagreb, Croatia.
Relja
M
M
Lacković
Z
Z
D000818:Animals; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D008297:Male; D010146:Pain / Q000188:drug therapy* / Q000503:physiopathology; D010147:Pain Measurement / Q000187:drug effects / Q000379:methods; D010523:Peripheral Nervous System Diseases / Q000188:drug therapy* / Q000503:physiopathology; D051381:Rats; D017208:Rats, Wistar; D020426:Sciatic Neuropathy / Q000188:drug therapy / Q000503:physiopathology
D019274:Botulinum Toxins, Type A