Heterochromatin focuses on senescence.
A key step in cellular senescence is the packaging of proliferation-promoting genes into repressive chromatin or heterochromatin. Recent work has described a novel histone component and mode of assembly of this senescence-associated heterochromatin.
Schulz
Laura
L
Department of Biochemistry and Molecular Genetics, University of Colorado Health Sciences Center, Aurora, CO 80045, USA.
Tyler
Jessica
J
D049109:Cell Proliferation; D016922:Cellular Senescence / Q000235:genetics*; D006570:Heterochromatin / Q000378:metabolism*; D006657:Histones / Q000378:metabolism*; D006801:Humans; D008957:Models, Genetic; D009690:Nucleic Acid Conformation
D006570:Heterochromatin; D006657:Histones; C120756:macroH2A histone