title: [A case report of Churg-Strauss syndrome combined with various vessel diseases].
abstract: A 73-year-old woman with a three-year history of allergic rhinitis and bronchial asthma was found to have Churg-Strauss syndrome combined with fever, eosinophilia, mononeuritis multiplex, and acute coronary syndrome. After the treatment with a methylprednisolone pulse therapy and a high dose of corticosteroids were initiated, eosinophilia normalized together with decline of fever, but acute superior mesenteric artery occlusion occurred, which improved with conservative therapy. Severe stenosis of bilateral carotid arteries was found, so immunosuppressive drugs were added. In general, Churg-Strauss syndrome is a disease with vasculitis affecting small arteries, arterioles, venules, or capillaries, and cases with arteritis in large and medium-sized arteries, such as this case are rare. This suggested that in cases of Churg-Strauss syndrome of the elderly patients, physicians must be careful about involvement of larger vessels.
authors.affiliation: Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Omoto
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Kawahito
authors.forename: Naoko
authors.initials: N
authors.lastname: Muraguchi
authors.forename: Toshitatsu
authors.initials: T
authors.lastname: Takao
authors.forename: Aihiro
authors.initials: A
authors.lastname: Yamamoto
authors.forename: Mizuho
authors.initials: M
authors.lastname: Kimura
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Tsubouchi
authors.forename: Mamoru
authors.initials: M
authors.lastname: Inoue
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Yoshikawa
mesh_terms: D000368:Aged; D016893:Carotid Stenosis / Q000209:etiology*; D015267:Churg-Strauss Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D008641:Mesenteric Vascular Occlusion / Q000209:etiology*; D009203:Myocardial Infarction / Q000209:etiology*