title: Long-term remission of excessive liver metastases in a breast cancer patient with chronic alcohol abuse using a monotherapy with trastuzumab.
abstract: We report on the successful treatment of a 43-year-old breast cancer patient with excessive liver metastases and chronic alcohol abuse. After first occurrence of hepatic metastases, systemic and interventional therapies were performed, and resulted in short-term partial remission. Finally, an excessive progression of the hepatic metastases was diagnosed. A systemic therapy with weekly trastuzumab (Herceptin) infusions was induced and a complete remission was achieved that is ongoing now for over 45 months.
authors.affiliation: Department of Gynecology and Obstetrics, University of Heidelberg Medical School, Heidelberg, Germany. Michael_Eichbaum@med.uni-heidelberg.de
authors.forename: Michael H R
authors.initials: MH
authors.lastname: Eichbaum
authors.forename: Andreas
authors.initials: A
authors.lastname: Schneeweiss
authors.forename: Gunther
authors.initials: G
authors.lastname: Bastert
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000473:pathology*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000556:secondary*; D012074:Remission Induction; D000068878:Trastuzumab
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D000068878:Trastuzumab