title: Headache attributed to spontaneous low CSF pressure: report of three cases responsive to corticosteroids.
abstract: The therapy of headache attributed to spontaneous low CSF pressure (previously defined as spontaneous intracranial hypotension) is still a matter of debate. Epidural blood patch is considered the most effective treatment. However, pharmacological strategies may be considered before blood patch. We report three patients with headache attributed to spontaneous low CSF pressure that were successfully treated with oral prednisone. Additional studies may be useful to prove the effectiveness of corticosteroids in this syndrome.
authors.affiliation: Neurology III -- Headache Center, Department of Neuroscience, University of Torino, Torino, Italy. sgentile@molinette.piemonte.it
authors.forename: S
authors.initials: S
authors.lastname: Gentile
authors.forename: R Lo
authors.initials: RL
authors.lastname: Giudice
authors.forename: P De
authors.initials: PD
authors.lastname: Martino
authors.forename: I
authors.initials: I
authors.lastname: Rainero
authors.forename: L
authors.initials: L
authors.lastname: Pinessi
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D015170:Cerebrospinal Fluid Pressure / Q000187:drug effects; D005260:Female; D006261:Headache / Q000188:drug therapy* / Q000209:etiology* / Q000473:pathology; D006801:Humans; D019585:Intracranial Hypotension / Q000150:complications* / Q000473:pathology; D007427:Intracranial Pressure / Q000187:drug effects; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use*
chemical_list: D000305:Adrenal Cortex Hormones; D011241:Prednisone