title: Targeting the cranial nerve: microradiosurgery for trigeminal neuralgia with CISS and 3D-flash MR imaging sequences.
abstract: OBJECTIVE
  The authors undertook a study to identify magnetic resonance (MR) imaging techniques that can be used reliably during gamma knife surgery (GKS) to identify the trigeminal nerve, surrounding vasculature, and areas of compression.
  
  
  METHODS
  Preoperative visualization of the trigeminal nerve and surrounding vasculature as well as targeting the area of vascular compression may increase the effectiveness of GKS for trigeminal neuralgia. During the past years our gamma knife centers have researched different MR imaging sequences with regard to their ability to visualize cranial nerves and vascular structures. Constructive interference in steady-state (CISS) fusion imaging with three-dimensional gradient echo sequences (3D-Flash) was found to be of greatest value in the authors' 25 most recent patients. In 24 (96%) out of the 25 patients, the fifth cranial nerve, surrounding vessels, and areas of compression could be reliably identified using CISS/3D-Flash. The MR images were acceptable despite patients' history of microvascular decompression, radiofrequency (RF) ablation, or concomitant disease. In one of 25 patients with a history of multiple RF lesions, the visualization was inadequate due to severe trigeminal nerve atrophy.
  
  
  CONCLUSIONS
  The CISS/3D-Flash fusion imaging has become the preferred imaging method at the authors' institutions during GKS for trigeminal neuralgia. It affords the best visualization of the trigeminal nerve, surrounding vasculature, and the precise location of vascular compression.
authors.affiliation: Department of Neurosurgery, Tufts University, Boston, Massachusetts, USA. vaszerris@yahoo.com
authors.forename: Vasilios A
authors.initials: VA
authors.lastname: Zerris
authors.forename: Georg C
authors.initials: GC
authors.lastname: Noren
authors.forename: William A
authors.initials: WA
authors.lastname: Shucart
authors.forename: Jeff
authors.initials: J
authors.lastname: Rogg
authors.forename: Gerhard M
authors.initials: GM
authors.lastname: Friehs
mesh_terms: D001284:Atrophy / Q000473:pathology / Q000601:surgery; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008866:Microsurgery / Q000295:instrumentation*; D011300:Preoperative Care; D016634:Radiosurgery / Q000295:instrumentation*; D014277:Trigeminal Neuralgia / Q000134:cerebrospinal fluid / Q000473:pathology / Q000601:surgery*