title: Genetic selection for susceptibility to oral tolerance leads to a profound reduction of the acute inflammatory response.
abstract: Strains of mice obtained by genetic selection to extremes of phenotype for susceptibility or resistance to oral tolerance were investigated for possible genetic correlations with acute inflammatory response using different models of inflammation. The results show a strong genetic association.
authors.affiliation: Laboratório de Imunobiologia, Departamento Biologia Celular e Genética, Instituto de Biologia, UERJ, Rua S. Francisco Xavier, 524, PHLC, Maracanã, Rio de Janeiro, RJ, Brasil, CEP 20.559-900. dasilva@uerj.br
authors.forename: Maria de Fátima Sarro
authors.initials: Mde F
authors.lastname: da Silva
authors.forename: Alberto
authors.initials: A
authors.lastname: da Nóbrega
authors.forename: Tereza Cristina
authors.initials: TC
authors.lastname: Barja-Fidalgo
authors.forename: Aline C
authors.initials: AC
authors.lastname: Brando-Lima
authors.forename: Fernando
authors.initials: F
authors.lastname: Cunha
authors.forename: Antonio Carlos
authors.initials: AC
authors.lastname: da Silva
mesh_terms: D000208:Acute Disease; D000818:Animals; D000941:Antigens / Q000276:immunology; D004198:Disease Susceptibility / Q000276:immunology*; D007108:Immune Tolerance; D018928:Immunity, Mucosal; D007249:Inflammation / Q000276:immunology* / Q000517:prevention & control; D008070:Lipopolysaccharides / Q000276:immunology / Q000633:toxicity; D051379:Mice; D009061:Mouth Mucosa / Q000276:immunology*; D010047:Ovalbumin / Q000276:immunology
chemical_list: D000941:Antigens; D008070:Lipopolysaccharides; D010047:Ovalbumin