Nanoscale borromean rings.
The molecular expression of topologically interesting structures represents a formidable challenge for synthetic chemists. The nontrivial link known as the Borromean rings has long been regarded as one of the most ambitious targets in this field. Of ancient provenance, this symbol comprises three interlocked rings in an inseparable union, but cut any one of the rings and the whole assembly unravels into three separate pieces. This Account delineates different strategies that can be applied to the formation of molecules possessing this distinctive topology, culminating with two successful syntheses of such compounds, thus cutting the Gordian knot of topological chemistry.
Cantrill
Stuart J
SJ
California NanoSystems Institute and Department of Chemistry and Biochemistry, University of California, Los Angeles, 405 Hilgard Avenue, Los Angeles, California 90095-1569, USA.
Chichak
Kelly S
KS
Peters
Andrea J
AJ
Stoddart
J Fraser
JF
D015082:2,2'-Dipyridyl / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D000473:Alkanes / Q000737:chemistry; D018360:Crystallography, X-Ray; D003500:Cyclization; D004247:DNA / Q000737:chemistry*; D004987:Ethers / Q000737:chemistry; D008024:Ligands; D008958:Models, Molecular; D036103:Nanotechnology; D009690:Nucleic Acid Conformation; D000644:Quaternary Ammonium Compounds / Q000737:chemistry
D000473:Alkanes; D004987:Ethers; D008024:Ligands; D000644:Quaternary Ammonium Compounds; D015082:2,2'-Dipyridyl; D004247:DNA