title: Internal filtration-enhanced hemodialysis is a cost-effective treatment in view of solute removal.
abstract: By modifying dialyzer module design, internal filtration (IF) within a dialyzer is enhanced to increase convective solute transport. Thus, it can be an alternative to hemodiafiltration with no requirement of substitution fluid or additional complex machines. Cost-effective analysis was conducted in three modes of therapy: high-flux hemodialysis, on-line hemodiafiltration and IF-enhanced hemodialysis. In IF-enhanced hemodialysis, cost-effectiveness of small solute removal is comparable with high-flux hemodialysis and that of beta(2)-microglobulin removal is the best. It is concluded that IF-enhanced hemodialysis is the most cost-effective therapy mode in comprehensive overall solute removal.
authors.affiliation: Koda Medical and Dialysis Clinic, Niigata, Japan. wg8y-kud@asahi-net.or.jp
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Koda
mesh_terms: D003362:Cost-Benefit Analysis; D004867:Equipment Design; D017583:Hemodiafiltration / Q000191:economics / Q000379:methods; D006440:Hemofiltration / Q000191:economics / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D006435:Renal Dialysis / Q000191:economics / Q000379:methods*; D001613:beta 2-Microglobulin / Q000097:blood
chemical_list: D001613:beta 2-Microglobulin