Structure elucidation and synthesis of lycoposerramine-B, a novel oxime-containing Lycopodium alkaloid from Lycopodium serratum Thunb.
A new alkaloid, lycoposerramine-B (1), containing an oxime function, was isolated from the club moss Lycopodium serratum Thunb. The structure of 1 was elucidated by spectroscopic analysis, including J-resolved HMBC spectroscopy, and confirmed by its synthesis from the known alkaloid, serratinine (3).
Katakawa
Kazuaki
K
Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.
Kitajima
Mariko
M
Aimi
Norio
N
Seki
Hiroko
H
Yamaguchi
Kentaro
K
Furihata
Kazuo
K
Harayama
Takashi
T
Takayama
Hiromitsu
H
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D002236:Carbohydrate Conformation; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D007212:Indolizines / Q000737:chemistry*; D032502:Lycopodium / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010091:Oximes / Q000138:chemical synthesis* / Q000737:chemistry*
D000470:Alkaloids; D006575:Heterocyclic Compounds, 3-Ring; D007212:Indolizines; D010091:Oximes; C497861:lycoposerramine-B; C009245:serratinine