Investigations of the halogen dance reaction on N-substituted 2-thiazolamines.
The halogen dance (HD) reaction on various 2-thiazolamine systems was investigated providing an easy access to a series of 5-substituted 4-bromo-2-thiazolamine derivatives. We could show that HD is a very favored process for the investigated systems and that prevention of HD is only possible when optimized reaction conditions and selected electrophiles are applied.
Stanetty
Peter
P
Vienna University of Technology, Institute of Applied Synthetic Chemistry and Institute for Chemical Technology and Analytics, Getreidemarkt 9/163, A-1060 Vienna, Austria. peter.stanetty@tuwien.ac.at
Schnürch
Michael
M
Mereiter
Kurt
K
Mihovilovic
Marko D
MD