title: Botulinum toxin injections in the treatment of musician's dystonia.
abstract: The authors present the results of 84 musicians with focal task-specific dystonia treated with EMG-guided botulinum toxin injections. Treatment outcome was assessed by subjective estimation of playing before and after treatment and self-rating of treatment response. Fifty-eight (69%) of the musicians experienced improvement from the injections and 30 of 84 musicians (36%) reported long-term benefit in their performance ability.
authors.affiliation: Department of Neurology and Medical Center for Performing Artists/Mailbox S 432, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA. schules@ccf.org
authors.forename: Stephan
authors.initials: S
authors.lastname: Schuele
authors.forename: Hans-Christian
authors.initials: HC
authors.lastname: Jabusch
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Lederman
authors.forename: Eckart
authors.initials: E
authors.lastname: Altenmüller
mesh_terms: D000328:Adult; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage / Q000627:therapeutic use*; D012090:Cumulative Trauma Disorders / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D004341:Drug Evaluation; D020821:Dystonic Disorders / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D004576:Electromyography; D005260:Female; D005385:Fingers / Q000294:innervation; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D009044:Motor Cortex / Q000503:physiopathology; D009146:Music; D009473:Neuronal Plasticity; D009784:Occupational Diseases / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D010276:Parasympatholytics / Q000008:administration & dosage / Q000627:therapeutic use*; D017060:Patient Satisfaction; D012189:Retrospective Studies; D013003:Somatosensory Cortex / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D010276:Parasympatholytics; D019274:Botulinum Toxins, Type A