title: [Inmunohistochimic expresion of p53 protein and TTS prognostic value in the larynx cancer].
abstract: We carried out an immunohistochemical study of p53 (DO7) expression in a series of 195 patients with laryngeal squamous cell carcinoma, treated and followed at the Department of Otolaryngology Virgen de la Salud Hospital (Toledo, Spain). In the cases with lymph node metastasis we also studied p53 expression at this site. We have investigated the value of p53 expression as a prognostic factor (tumor recurrence, deads due tu cancer and survival) and we have evaluated the relationship between p53 expression and other clinicopathologic characteristics.
authors.affiliation: Servicio ORL. Hospital Gutiérrez Ortega. Valdepeñas, Ciudad Real. cjangela@castillalamancha.es
authors.forename: M C
authors.initials: MC
authors.lastname: García Lozano
authors.forename: J L
authors.initials: JL
authors.lastname: Orradre Romero
authors.forename: M
authors.initials: M
authors.lastname: Caro García
authors.forename: A I
authors.initials: AI
authors.lastname: Sáez del Castillo
authors.forename: M A
authors.initials: MA
authors.lastname: Piris Pinilla
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007822:Laryngeal Neoplasms / Q000235:genetics* / Q000276:immunology* / Q000473:pathology; D008297:Male; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011379:Prognosis; D016159:Tumor Suppressor Protein p53 / Q000235:genetics* / Q000276:immunology*
chemical_list: D016159:Tumor Suppressor Protein p53