title: Management of hepatitis C patients: a French population-based study.
abstract: OBJECTIVE
  Our aim was to assess the proportion of patients in a well-defined population reaching specialized medical care after hepatitis C diagnosis.
  
  
  METHODS
  Hepatitis C-positive patients recorded in the population-based registry of Cote-d'Or, an administrative district in France, constituted the study population.
  
  
  RESULTS
  Between 1994 and 1999, new hepatitis C-positive serology was diagnosed in 847 patients, of whom 690 were eligible for this study. A total of 135 patients had not been given specialized medical care after diagnosis; among them, 50.4% had a normal serum alanine transferase level at diagnosis, 62.2% had risk factors related to lifestyle (drug addiction, sexual risk...), and 26.7% were current alcoholics. The 555 other patients were involved in specialized medical care after diagnosis: 42.7% had a liver biopsy and 27.0% were treated. Treatment was carried out more often in males than in females (OR: 1.67; P<0.005), and in patients less than 65 years old (OR: 2.94; P<0.0002). Nearly 30.5% of patients with a Metavir score greater than A1F1 did not undergo treatment.
  
  
  CONCLUSIONS
  This study shows that in a general population at least one patient out of five with hepatitis C infection remains outside the health care system. It also reveals that management practices vary with gender. Further surveys are needed to better understand this phenomenon.
authors.affiliation: EPI INSERM 0106, Centre d'Epidémiologie de Population, Faculté de Médecine, BP 87900, 21079 Dijon Cedex.
authors.forename: Cyril
authors.initials: C
authors.lastname: Hatem
authors.forename: Anne
authors.initials: A
authors.lastname: Minello
authors.forename: Laurent
authors.initials: L
authors.lastname: Martin
authors.forename: Valérie
authors.initials: V
authors.lastname: Jooste
authors.forename: Isabelle
authors.initials: I
authors.lastname: Beurton
authors.forename: Chantal
authors.initials: C
authors.lastname: Milan
authors.forename: Claire
authors.initials: C
authors.lastname: Bonithon-Kopp
authors.forename: Solange
authors.initials: S
authors.lastname: Bresson-Hadni
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Miguet
authors.forename: Patrick
authors.initials: P
authors.lastname: Hillon
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005602:France; D006526:Hepatitis C / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged