title: Two diterpenes and three diterpene glucosides from Phlogacanthus curviflorus.
abstract: Two new diterpene lactones, phlogacantholides B (1) and C (2), and three new diterpene lactone glucosides, phlogacanthosides A (3), B (4), and C (5), together with lupeol, beta-sitosterol, betulin, beta-daucosterol, (+)-syringaresinol, and (+)-syringaresinol-4-O-beta-D-glucopyranoside, were isolated from the roots of Phlogacanthus curviflorus. Their structures were elucidated by chemical and spectroscopic evidence. The structure, including the relative configuration of phlogacantholide B (1), was confirmed by X-ray crystallographic analysis of its diacetate (6).
authors.affiliation: Chengdu Institute of Biology, The Chinese Academy of Sciences, Chengdu 610041, People's Republic of China.
authors.forename: Xiao-Hong
authors.initials: XH
authors.lastname: Yuan
authors.forename: Bo-Gang
authors.initials: BG
authors.lastname: Li
authors.forename: Xiu-Yun
authors.initials: XY
authors.lastname: Zhang
authors.forename: Hua-Yi
authors.initials: HY
authors.lastname: Qi
authors.forename: Min
authors.initials: M
authors.lastname: Zhou
authors.forename: Guo-Lin
authors.initials: GL
authors.lastname: Zhang
mesh_terms: D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D004224:Diterpenes; D004365:Drugs, Chinese Herbal; D005960:Glucosides