title: Progression from anomalous optic discs to visible optic disc drusen.
abstract: At age 5, a patient underwent fundus photography that disclosed elevated optic discs without drusen. A head computed tomography did not show optic nerve calcification. At age 9, no disc drusen were evident by ophthalmoscopy, but a CT now showed optic nerve calcification. At age 12, optic disc drusen were faintly evident on photographs; visual fields showed blind spot enlargement OD and an arcuate defect OS. At age 21, he had numerous discrete disc drusen in both eyes, disc pallor, and slight progression of the visual field defects. This case documents the progression from anomalous optic discs to ophthalmoscopically visible optic nerve drusen over a 16-year period.
authors.affiliation: Department of Ophthalmology, John A. Moran Eye Center, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA.
authors.forename: Terrence S
authors.initials: TS
authors.lastname: Spencer
authors.forename: Bradley J
authors.initials: BJ
authors.lastname: Katz
authors.forename: Steve W
authors.initials: SW
authors.lastname: Weber
authors.forename: Kathleen B
authors.initials: KB
authors.lastname: Digre
mesh_terms: D000328:Adult; D000375:Aging / Q000502:physiology; D018450:Disease Progression; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009887:Ophthalmoscopy / Q000379:methods; D009898:Optic Disk / Q000002:abnormalities*; D015594:Optic Disk Drusen / Q000209:etiology* / Q000473:pathology; D009900:Optic Nerve / Q000473:pathology / Q000503:physiopathology; D014794:Visual Fields / Q000502:physiology