High-resolution NMR for metabomics.
NMR spectroscopy has become a powerful tool for extensive qualitative and quantitative analysis, including temporal variations and system-wide assessment of all metabolites and small molecular components in complex mixtures of biological origin. In combination with additional analytical techniques, primarily mass spectrometry and chromatography methods, and with the support of involved statistical and other data analysis tools, NMR offers unprecedented insight into the biochemistry of living systems, and provides an outstanding tool for toxicology, disease diagnostics and risk assessment.
Pelczer
István
I
Princeton University, Department of Chemistry, Princeton, NJ 08544, USA. ipelczer@princeton.edu
D000818:Animals; D003627:Data Interpretation, Statistical; D023281:Genomics / Q000295:instrumentation*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D004364:Pharmaceutical Preparations / Q000378:metabolism*
D004364:Pharmaceutical Preparations