title: Unusual combination of presenting features in multiple myeloma.
abstract: Initial oral signs of multiple myeloma may involve pain, paraesthesia, swelling, tooth mobility and radiolucency. A 62-year-old female patient presented with the chief complaint of numbness in the right lower jaw. Intraoral examination revealed no abnormalities and her history was non-contributory. A panoramic radiograph revealed an irregular, small radiopacity in the premolar region and small, multiple and diffuse osteolytic alterations in the mandible. Computed tomography revealed maxillary and mandibular cortical destruction. An incisional biopsy was performed. The histopathological diagnosis was plasma cell myeloma and further investigations lead to the diagnosis of multiple myeloma. Dysfunction of a nerve coursing through diseased bone is an ominous sign and may be an indication that a malignant process is present.
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Dentistry, Suleyman Demirel University, Isparta, Turkey.
authors.forename: T
authors.initials: T
authors.lastname: Baykul
authors.forename: U
authors.initials: U
authors.lastname: Aydin
authors.forename: M K
authors.initials: MK
authors.lastname: O Carroll
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000000981:diagnostic imaging* / Q000473:pathology; D011862:Radiography, Panoramic; D012888:Skull Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D036542:Tomography, Spiral Computed