title: [Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura--the associateion between the activity of Helicobacter pylori and platelet recovery].
abstract: We investigated the prevalence of Helicobacter pylori infection and the effect of eradication therapy in patients with idiopathic thrombocytopenic purpura (ITP). H. pylori infection was found in 9 of 11 patients (81.8%). H. pylori eradication was obtained in all patients and significant platelet recovery was found in 5 of 9 patients (55.6%). One patient required re-eradication therapy because the urea breath test remained positive after the first therapy. After complete eradication, long time remission was obtained. The results suggested that the platelet count might be correlated closely with the amount of H. pylori in some patients with H. pylori positive ITP.
authors.affiliation: Division of Hematology, Jichi Medical School.
authors.forename: Kazuya
authors.initials: K
authors.lastname: Sato
authors.forename: Tadashi
authors.initials: T
authors.lastname: Nagai
authors.forename: Kazuo
authors.initials: K
authors.lastname: Muroi
authors.forename: Norio
authors.initials: N
authors.lastname: Komatsu
authors.forename: Keiya
authors.initials: K
authors.lastname: Ozawa
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D016481:Helicobacter Infections / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000188:drug therapy / Q000209:etiology*