Detection of KPC carbapenem-hydrolyzing enzymes in Enterobacter spp. from Brooklyn, New York.
Enterobacter spp. are rarely resistant to carbapenems. In this report, one Enterobacter sp. isolate possessed bla(KPC-3) and two possessed bla(KPC-2). For all three strains, the imipenem MICs were dependent on the inoculum and testing method; two were reported by the clinical laboratories to be carbapenem susceptible. Improved detection methods will be necessary to identify these enzymes.
Bratu
Simona
S
Division of Infectious Diseases, State University of New York-Downstate, Box 77, 450 Clarkson Ave., Brooklyn, NY 11203, USA.
Landman
David
D
Alam
Maqsood
M
Tolentino
Elaine
E
Quale
John
J
D015780:Carbapenems / Q000378:metabolism*; D024881:Drug Resistance, Bacterial; D004591:Electrophoresis, Polyacrylamide Gel; D004754:Enterobacter / Q000201:enzymology*; D006801:Humans; D007525:Isoelectric Focusing; D008826:Microbial Sensitivity Tests; D009519:New York City; D014946:Wound Infection / Q000382:microbiology; D001618:beta-Lactamases / Q000737:chemistry / Q000235:genetics*
D015780:Carbapenems; C491478:beta-lactamase KPC-2; D001618:beta-Lactamases; C498060:beta-lactamase KPC-3, Enterobacter cloacae