title: Osseous metaplasia in a tubular adenoma of the colon.
abstract: An 85 year old woman presented with a one month history of change in her bowel habits in the form of alternating diarrhoea and constipation. She also noted some rectal bleeding. Flexible sigmoidoscopy revealed a 1.5 cm polyp 30 cm from the anus. The polyp was removed during the sigmoidoscopy by electrocautery and sent for histological examination. The polyp was a tubular adenoma with mild dysplasia. The adenoma contained numerous foci of metaplastic bone. These consisted of irregular islands of mineralised osteoid bone rimmed by a layer of scattered osteoblasts. This is the first case of osseous metaplasia in a tubular adenoma of the colon to be reported.
authors.affiliation: Department of Histopathology, East Lancashire Hospitals, Burnley BB10 2PQ, UK. waldaraji@aol.com
authors.forename: W I
authors.initials: WI
authors.lastname: Al-Daraji
authors.forename: A
authors.initials: A
authors.lastname: Abdellaoui
authors.forename: W D
authors.initials: WD
authors.lastname: Salman
mesh_terms: D000236:Adenoma / Q000473:pathology*; D000368:Aged; D000369:Aged, 80 and over; D003106:Colon / Q000473:pathology; D003110:Colonic Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008679:Metaplasia / Q000473:pathology; D009999:Ossification, Heterotopic / Q000473:pathology*