title: Non-neoplastic, degenerative brain pathologies and fibroses diagnosed on the basis of ultra-small samples obtained by stereotactic biopsy.
abstract: Brain biopsy and other stereotactic procedures have evolved over the last decades. Recently, the morbidity and mortality decreased radically along with an increase in the number of successful histopathological diagnoses. Therefore, applications of appropriate treatments in neoplastic brain pathologies are now possible, especially of those located in deep regions. Stereotactic biopsy may also be used as a diagnostic method followed by appropriate management in conditions where a non-neoplastic pathology is suspected. Between December 2000 and February 2004, we performed 116 stereotactic procedures based on the system of stereotactic planning and Brain-Lab treatment, which was equipped with automatic CT/MR image fusion software. In this report, we have focused on 10 cases of non-neoplastic brain pathologies diagnosed on the basis of ultra-small samples obtained from stereotactic biopsy. Among them there were 4 cases of gliosis, 3 cases of brain degenerative disorders, 2 cases of hippocampal fibroses, and 1 case of normal brain tissue. We have presented all these cases in detail by discussing their histology, clinical manifestations, localisation, management and follow-up.
authors.affiliation: Department of Neurosurgery, Medical University of Silesia, Katowice, Poland. skwiek@csk.katowice.pl
authors.forename: Stanisław J
authors.initials: SJ
authors.lastname: Kwiek
authors.forename: Grazyna
authors.initials: G
authors.lastname: Bierzyńska-Macyszyn
authors.forename: Paweł
authors.initials: P
authors.lastname: Właszczuk
authors.forename: Piotr
authors.initials: P
authors.lastname: Bazowski
authors.forename: Bogusław
authors.initials: B
authors.lastname: Maciejewski
authors.forename: Rafał
authors.initials: R
authors.lastname: Tarnawski
authors.forename: Wojciech
authors.initials: W
authors.lastname: Slusarczyk
authors.forename: Wojciech
authors.initials: W
authors.lastname: Kukier
authors.forename: Tomasz
authors.initials: T
authors.lastname: Wójcikiewicz
authors.forename: Abdullah
authors.initials: A
authors.lastname: Hayatullah
authors.forename: Izabela
authors.initials: I
authors.lastname: Duda
authors.forename: Dawid
authors.initials: D
authors.lastname: Larysz
authors.forename: Sławomir
authors.initials: S
authors.lastname: Blamek
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy / Q000009:adverse effects / Q000379:methods*; D001927:Brain Diseases / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D009493:Neurosurgery / Q000379:methods*; D014057:Tomography, X-Ray Computed