title: Effect of Haimiding on the functioning of red cell membrane of FC and H22 tumor-bearing mice.
abstract: OBJECTIVE
  To study the effect of Haimiding on the functioning of red cell membrane of FC and H(22) tumor-bearing mice.
  
  
  METHODS
  The membrane fluidity of red cells is measured with DPH fluorescence probe as a marker; the amount of red cell membrane proteins is measured using polyacrylamide gel electrophoresis; the amount of sialic acid (SA) on the surface of red cell membrane and the sealability of these cells are measured using colorimetric analysis.
  
  
  RESULTS
  Haimiding can lower the membrane fluidity of red cells in tumor-bearing mice and the amount of their membrane proteins, while increasing the amount of sialic acid in the membrane of red cells in these mice and enhancing the ability of the membrane of their red cells to reseal.
  
  
  CONCLUSIONS
  The anti-tumor effect of Haimiding on tumor-bearing mice is due to its ability to improve and restore the functions of the membrane of their red cell and to enhance the immune effect of the organisms.
authors.affiliation: Postdoctoral Research Station, The Institute of Materia Medica, Harbin Commercial University, 138 Tongda Street, Daoli District, Harbin 150076, Heilongjiang Province, China. sygao2002@sina.com
authors.forename: Yu-Bin
authors.initials: YB
authors.lastname: Ji
authors.forename: Shi-Yong
authors.initials: SY
authors.lastname: Gao
authors.forename: Wei-Ping
authors.initials: WP
authors.lastname: Cheng
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D002448:Cell Adhesion / Q000187:drug effects / Q000276:immunology; D004910:Erythrocyte Membrane / Q000187:drug effects* / Q000378:metabolism; D005260:Female; D008113:Liver Neoplasms / Q000188:drug therapy*; D008297:Male; D008516:Medicine, Chinese Traditional; D008560:Membrane Fluidity / Q000187:drug effects*; D008565:Membrane Proteins / Q000378:metabolism; D051379:Mice; D008815:Mice, Inbred Strains; D019158:N-Acetylneuraminic Acid / Q000378:metabolism; D009368:Neoplasm Transplantation
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D008565:Membrane Proteins; D019158:N-Acetylneuraminic Acid