title: Histoenzymatic changes at splenic level in experimental enterovirosis.
abstract: An experimental model was established to observe the lymphoplasmocytic and macrophage reaction at distance, in spleen, following the intraperitoneal administration of Coxsackie B3 virus. In the aftermath of the experimental viral aggression the thymo-dependent immune system did not seem altered, while the thymo-independent one was severely challenged. The immune reaction of the humoral type was accompanied by a stimulation of the macrophagous type-cells.
authors.affiliation: Faculty of Medicine of Craiova.
authors.forename: F
authors.initials: F
authors.lastname: Bogdan
authors.forename: S
authors.initials: S
authors.lastname: Crăiţoiu
authors.forename: M
authors.initials: M
authors.lastname: Florescu
mesh_terms: D000818:Animals; D003384:Coxsackievirus Infections / Q000201:enzymology / Q000276:immunology* / Q000473:pathology; D008058:Dihydrolipoamide Dehydrogenase / Q000378:metabolism*; D008264:Macrophages / Q000201:enzymology / Q000473:pathology*; D008297:Male; D051381:Rats; D013154:Spleen / Q000201:enzymology / Q000473:pathology*; D013762:Tetrahydrofolate Dehydrogenase / Q000378:metabolism*
chemical_list: D013762:Tetrahydrofolate Dehydrogenase; D008058:Dihydrolipoamide Dehydrogenase