title: Protein localization studies in the age of 'Omics'.
abstract: As thousands of new genes are identified in genomics efforts, the rush is on to learn something about the functional roles of the proteins encoded by those genes. Clues to protein functions, activation states and protein-protein interactions have been revealed in focused studies of protein localization. With technical breakthroughs such as GFP protein tagging and recombinase cloning systems, large-scale screens of protein localization are now being undertaken.
authors.affiliation: Alliance for Cell Signaling, Microscopy Lab, Stanford University School of Medicine, 975 California Ave, Palo Alto, CA 94304, USA.
authors.forename: Nancy A
authors.initials: NA
authors.lastname: O'Rourke
authors.forename: Tobias
authors.initials: T
authors.lastname: Meyer
authors.forename: Grischa
authors.initials: G
authors.lastname: Chandy
mesh_terms: D000375:Aging / Q000235:genetics*; D000818:Animals; D023281:Genomics / Q000379:methods*; D049452:Green Fluorescent Proteins / Q000235:genetics / Q000378:metabolism; D006801:Humans; D011506:Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D015003:Yeasts / Q000235:genetics / Q000378:metabolism
chemical_list: D011506:Proteins; D049452:Green Fluorescent Proteins