title: Synthesis and characterization of polyester dendrimers from acetoacetate and acrylate.
abstract: New aliphatic polyester-type dendrimers were synthesized using a new AB2-type building block 3, prepared from benzyl acetoacetate and 2 equiv of tert-butyl acrylate by acetoacetic acid ester synthesis. The reiterative [deprotection by HCO2H, then EDCI/DMAP coupling] sequence using divergent growth method gave [G1]-4tBu-[G5]-64tBu dendrimers. 13C NMR relaxation time (T1) measurements on the carboxy carbons show that the extended chain conformations are predominant in CDCl3. [structure: see text]
authors.affiliation: Department of Biomolecular Science and School of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
authors.forename: Yuuki
authors.initials: Y
authors.lastname: Hirayama
authors.forename: Taisuke
authors.initials: T
authors.lastname: Nakamura
authors.forename: Satoshi
authors.initials: S
authors.lastname: Uehara
authors.forename: Yohko
authors.initials: Y
authors.lastname: Sakamoto
authors.forename: Kentaro
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Sei
authors.forename: Michiko
authors.initials: M
authors.lastname: Iwamura
mesh_terms: D000090:Acetoacetates; D000179:Acrylates; D050091:Dendrimers / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D011091:Polyesters / Q000138:chemical synthesis* / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D000090:Acetoacetates; D000179:Acrylates; D050091:Dendrimers; D011091:Polyesters; C016635:acetoacetic acid