title: [Study on ultrasonic extraction techniques of flavonoids in Chrysanthemum morifolium].
abstract: OBJECTIVE
  To optimize the ultrasonic extraction condition for flavonoids from Chrysanthemum morifolium.
  
  
  METHODS
  The extraction rate of flavonoids optimized condition (ethanol concentration, ultrasonic time, solvent quantity and extraction times) was determined by orthogonal design. UV-Spectrophotometry was used for the determination.
  
  
  RESULTS
  The order of factors to affect the flavonoid extraction was ethanol concentration > extraction times > solvent quantity > ultrasonic time.
  
  
  CONCLUSIONS
  The optimum ultrasonic extractions were: A2 B2 C3 D3. Compared with traditional extraction, ultraction method can save time, be easy to operate, improve extraction rates and need no heating.
authors.affiliation: College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Yin
authors.forename: Yong-zhou
authors.initials: YZ
authors.lastname: Hu
authors.forename: Xin-ji
authors.initials: XJ
authors.lastname: Yang
authors.forename: Jing
authors.initials: J
authors.lastname: Sheng
authors.forename: Zhen
authors.initials: Z
authors.lastname: Wang
mesh_terms: D031202:Chrysanthemum / Q000737:chemistry*; D005419:Flavonoids / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods*; D014465:Ultrasonics
chemical_list: D005419:Flavonoids