Depressive symptoms are independently predictive of carotid atherosclerosis.
The investigators tested whether depressive symptoms were predictive of carotid atherosclerosis, a marker of coronary atherosclerosis. Healthy participants (n = 219) underwent the baseline assessment of cardiovascular risk factors, including self-reported depressive symptoms, and were assessed for carotid plaque at 10-year follow-up. Adjusting for baseline cardiovascular risk factors, participants with elevated depression scores at baseline were >2 times as likely as those with no depressive symptoms to have carotid plaque.
Haas
Donald C
DC
Mount Sinai School of Medicine, New York, New York, USA. donald.haas@msnyuhealth.org
Davidson
Karina W
KW
Schwartz
Daniel J
DJ
Rieckmann
Nina
N
Roman
Mary J
MJ
Pickering
Thomas G
TG
Gerin
William
W
Schwartz
Joseph E
JE
D000328:Adult; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology*; D003863:Depression / Q000453:epidemiology*; D006801:Humans; D008875:Middle Aged; D009518:New York / Q000453:epidemiology; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D014463:Ultrasonography