Using obese mouse models in research: special considerations for IACUC members, animal care technicians, and researchers.
The mouse is the animal most commonly used to study the underlying causes of and treatments for obesity. The author reviews many of the issues that should be considered by all involved in research with mice expressing this phenotype, and describes some procedures exclusive to obesity research.
Good
Deborah J
DJ
Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA. goodd@vasci.umass.edu
D035661:Animal Care Committees; D000827:Animal Welfare / Q000592:standards*; D000818:Animals; D001831:Body Temperature; D001835:Body Weight; D004195:Disease Models, Animal; D004435:Eating; D005260:Female; D006799:Housing, Animal / Q000592:standards; D006801:Humans; D008297:Male; D051379:Mice; D018345:Mice, Knockout; D008817:Mice, Mutant Strains; D008820:Mice, Obese; D009043:Motor Activity; D009765:Obesity