[Advances in study on the pharmacological effects of active components of Chinese herbs on Alzheimer's disease].
Based on the pharmacological research of Chinese herbs on AD and some famous hypothesis on AD, such as dysfunction of nervous transmitter metabolism, apoptosis, inflammation etc, we consulted and analyzed relevant papers. We found the effective mechanism of Ginsenoside, Osthol, Rhodosin, and (-) Clausenamide were related to many pathological channels of AD, and Ginsenoside had effect on many pathological channels. The results have provided some clues for selecting effective herbs on AD.
Wu
Lei
L
DME Center, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, China. leiwu0972@sina.com
Cheng
Shu-yi
SY
Wang
Qi
Q
Chen
Yun-bo
YB
D000544:Alzheimer Disease / Q000378:metabolism / Q000473:pathology; D016229:Amyloid beta-Peptides / Q000096:biosynthesis; D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000494:pharmacology; D006801:Humans; D007858:Learning / Q000187:drug effects*; D009474:Neurons / Q000187:drug effects; D018377:Neurotransmitter Agents / Q000378:metabolism*; D010946:Plants, Medicinal / Q000737:chemistry
D016229:Amyloid beta-Peptides; D004365:Drugs, Chinese Herbal; D016166:Free Radical Scavengers; D018377:Neurotransmitter Agents