title: The Cooperative Outcomes Group for ENT: a multicenter prospective cohort study on the effectiveness of medical and surgical treatment for patients with chronic rhinosinusitis.
abstract: OBJECTIVE
  To assess outcomes for patients with chronic rhinosinusitis.
  
  
  METHODS
  Prospective, multicenter study; 31 otolaryngologists enrolled 276 adult patients with chronic rhinosinusitis; patients completed surveys at 3-month intervals, and physicians provided clinical and treatment data. The primary outcome measure was the Chronic Sinusitis Survey-Duration (CSS-D).
  
  
  RESULTS
  One hundred seventeen adult patients completed 12-month follow-up. Most patients reported sinus symptoms lasting longer than 3 years (74%). Patients showed significant improvement (group P < 0.0001) in the CSS-D score at each follow-up interval. Baseline CSS-D ( P < 0.0001), surgical intervention ( P < 0.003), and Lund-McKay score ( P < 0.04) were predictive of clinical success in regression analysis.
  
  
  CONCLUSIONS
  Patients referred to an otolaryngologist have a severe sinus illness. Treatment by an otolaryngologist was associated with significant improvement in sinus-related symptoms.
  
  
  CONCLUSIONS
  The study demonstrated the feasibility of multicenter outcome studies in chronic rhinosinusitis and generated testable hypotheses for future investigation.
  
  
  METHODS
  C.
authors.affiliation: Duke University Medical Center, Divison of Otolaryngology-Head and Neck Surgery, Durham Veterans Administration Medical Center, NC 27710, USA. witse001@mc.duke.edu
authors.forename: David L
authors.initials: DL
authors.lastname: Witsell
authors.forename: Michael G
authors.initials: MG
authors.lastname: Stewart
authors.forename: Edwin M
authors.initials: EM
authors.lastname: Monsell
authors.forename: James A
authors.initials: JA
authors.lastname: Hadley
authors.forename: Jeffrey E
authors.initials: JE
authors.lastname: Terrell
authors.forename: Maureen T
authors.initials: MT
authors.lastname: Hannley
authors.forename: Susan Sedory
authors.initials: SS
authors.lastname: Holzer
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D011446:Prospective Studies; D011788:Quality of Life; D012220:Rhinitis / Q000150:complications / Q000188:drug therapy* / Q000601:surgery*; D012852:Sinusitis / Q000150:complications / Q000188:drug therapy* / Q000601:surgery*; D013997:Time Factors