Wild chamomile (Matricaria recutita L.) mouthwashes in methotrexate-induced oral mucositis.
Oral mucositis is a known complication of methotrexate (MTX) therapy, but a single efficacious intervention or agent for prophylaxis or management of this side effect has not yet been identified. We report a case of MTX-induced oral mucositis in a patient with rheumatoid arthritis, who was successfully treated with Wild chamomile mouthwashes.
Mazokopakis
E E
EE
Department of Internal Medicine, University General Hospital of Heraklion Crete, P.O. Box 1352, 71110 Heraklion, Crete, Greece.
Vrentzos
G E
GE
Papadakis
J A
JA
Babalis
D E
DE
Ganotakis
E S
ES
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D005260:Female; D035264:Flowers; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D031168:Matricaria; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects*; D009067:Mouthwashes / Q000008:administration & dosage / Q000627:therapeutic use*; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000627:therapeutic use*; D013280:Stomatitis / Q000139:chemically induced / Q000188:drug therapy*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007166:Immunosuppressive Agents; D009067:Mouthwashes; D010936:Plant Extracts; D008727:Methotrexate