title: Benign fibrous histiocytoma of the mandible.
abstract: A very rare case of benign fibrous histiocytoma of the mandible is presented. A 49-year-old woman was admitted because of left buccal swelling and pain. Panoramic radiograph showed well-demarcated soap-bubble appearance without sclerotic rim in the left mandibular bone. A yellowish-white and partly brown solid tumor was noted in the excised mandibular bone specimen. The tumor histologically consisted of spindle cells, in which areas showing a storiform pattern and other areas composed of histiocytic cells with erythrophagocytosis and foam cells were mixed. Immunohistochemically, the tumor cells were positive for vimentin, CD68, alpha-1-antichymotrypsin and alpha-1-antitrypsin. From these findings the tumor was diagnosed as a primary BFH of the mandible. No recurrence has been noted 2 years and 11 months after surgery.
authors.affiliation: Department of Oral Pathology, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan.
authors.forename: Mitsunobu
authors.initials: M
authors.lastname: Kishino
authors.forename: Shumei
authors.initials: S
authors.lastname: Murakami
authors.forename: Satoru
authors.initials: S
authors.lastname: Toyosawa
authors.forename: Atsutoshi
authors.initials: A
authors.lastname: Nakatani
authors.forename: Yuzo
authors.initials: Y
authors.lastname: Ogawa
authors.forename: Takeshi
authors.initials: T
authors.lastname: Ishida
authors.forename: Naokuni
authors.initials: N
authors.lastname: Ijuhin
mesh_terms: D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D005260:Female; D005487:Foam Cells / Q000473:pathology; D005500:Follow-Up Studies; D006644:Histiocytes / Q000473:pathology; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology*; D006801:Humans; D008264:Macrophages / Q000473:pathology; D008339:Mandibular Neoplasms / Q000473:pathology*; D008875:Middle Aged; D010587:Phagocytosis; D011862:Radiography, Panoramic; D014746:Vimentin / Q000032:analysis; D000514:alpha 1-Antichymotrypsin / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis; D000097382:CD68 Molecule
chemical_list: D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D014746:Vimentin; D000514:alpha 1-Antichymotrypsin; D000515:alpha 1-Antitrypsin; C067980:CD68 antigen, human; D000097382:CD68 Molecule