title: [Infrared spectrum and nuclear magnetic resonance analysis of the alkaloid extract of Gelsemium produced in east Guangdong province].
abstract: OBJECTIVE
  To identify the structure of the alkaloid extract of Gelsemium from east Guangdong province of China.
  
  
  METHODS
  Fourier transform infrared (FTIR) absorption spectrometry, hydrogen and carbon spectra of nuclear magnetic resonance (NMR) and distortionless enhancement by polarization transfer (DEPT) analysis were used for the structural identification of the alkaloid exstract of Gelsemium.
  
  
  RESULTS
  The frequency, intensity and shape of the extract's characteristic peaks in infrared absorption spectra (4,000.0-400.0 cm(-1)) and (1)H NMR, (13)C NMR were recognized and compared. The molecular structure of the sample was consistent with the theoretically derived model.
  
  
  CONCLUSIONS
  The extract is structurally identical to koumine, which may provide evidence for its safe clinical application and establishment of Chinese medicine fingerprint database of Gelsemium.
authors.affiliation: Department of Pharmaceutics, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. wangzr@fimmu.com
authors.forename: Zhi-rui
authors.initials: ZR
authors.lastname: Wang
authors.forename: Lan-lan
authors.initials: LL
authors.lastname: Zhang
authors.forename: Chang-quan
authors.initials: CQ
authors.lastname: Huang
authors.forename: Zhong-yi
authors.initials: ZY
authors.lastname: Zhang
authors.forename: Jing-ming
authors.initials: JM
authors.lastname: Lin
mesh_terms: D000470:Alkaloids / Q000032:analysis / Q000737:chemistry* / Q000302:isolation & purification; D002681:China; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D031450:Gelsemium / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013055:Spectrophotometry, Infrared
chemical_list: D000470:Alkaloids; D004365:Drugs, Chinese Herbal