title: Effect of humidified and heated CO2 during gynecologic laparoscopic surgery on analgesic requirements and postoperative pain.
abstract: OBJECTIVE
  To determine the effect of humidified and heated CO(2) for pneumoperitoneum during laparoscopic surgery on analgesic requirements, postoperative pain, and patient satisfaction.
  
  
  METHODS
  Prospective, randomized, double-blind, controlled study (Canadian Task Force classification I).
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Ninety consecutive women scheduled for gynecologic laparoscopic surgery.
  
  
  METHODS
  Operative laparoscopic management of adnexa surgery or adhesiolysis.
  
  
  RESULTS
  Thirty consecutive patients were randomized into each study group. Group I received humidified, heated gas; group II dry, heated gas; and group III (control group) standard dry, cold gas. No significant difference in intraoperative and postoperative analgesic requirements or postoperative pain score between group I and group II was found. There was even a tendency (not significant) toward less pain and higher postoperative satisfaction in patients in the control group. Therefore, the evaluation was stopped after 53 patients.
  
  
  CONCLUSIONS
  The use of humidified, heated gas did not reduce postoperative pain or intraoperative analgesic requirements and is thus not preferable to standard dry, cold gas in gynecologic laparoscopic surgery.
authors.affiliation: Division of Gynecologic Endocrinology and Reproductive Medicine, Department of Obstetrics and Gynecology, Johann Wolfgang Goethe-University, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Kissler
authors.forename: Marianne
authors.initials: M
authors.lastname: Haas
authors.forename: Renate
authors.initials: R
authors.lastname: Strohmeier
authors.forename: Hubert
authors.initials: H
authors.lastname: Schmitt
authors.forename: Achim
authors.initials: A
authors.lastname: Rody
authors.forename: Manfred
authors.initials: M
authors.lastname: Kaufmann
authors.forename: Ernst
authors.initials: E
authors.lastname: Siebzehnruebl
mesh_terms: D000290:Adnexa Uteri / Q000601:surgery; D000328:Adult; D002245:Carbon Dioxide / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006358:Hot Temperature / Q000627:therapeutic use*; D006801:Humans; D006813:Humidity; D007263:Infusions, Parenteral; D010535:Laparoscopy / Q000379:methods*; D010149:Postoperative Pain / Q000188:drug therapy* / Q000517:prevention & control*; D011027:Pneumoperitoneum; D011028:Pneumoperitoneum, Artificial / Q000379:methods; D011446:Prospective Studies; D016896:Treatment Outcome
chemical_list: D002245:Carbon Dioxide