title: Spiro-annulation of barbituric acid derivatives and its analogs by ring-closing metathesis reaction.
abstract: Barbituric acid 1 and related beta-dicarbonyl compounds were dialkenylated under the phase-transfer catalyst [e.g., benzyltriethylammonium chloride (BTEAC)] conditions to generate the diallylated products. These diallylated products were subjected to the ring-closing metathesis (RCM) reaction to deliver the corresponding spiro-annulated derivatives.
authors.affiliation: Department of Chemistry, Indian Institute of Technology-Bombay, Powai, Mumbai 400076, India.
authors.forename: Sambasivarao
authors.initials: S
authors.lastname: Kotha
authors.forename: Ashoke Chandra
authors.initials: AC
authors.lastname: Deb
authors.forename: Ramanatham Vinod
authors.initials: RV
authors.lastname: Kumar
mesh_terms: D001463:Barbiturates / Q000138:chemical synthesis*; D003500:Cyclization; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013141:Spiro Compounds / Q000138:chemical synthesis*
chemical_list: D001463:Barbiturates; D013141:Spiro Compounds; C032232:barbituric acid