title: HbO-Arab mutation originated in the Pomak population of Greek Thrace.
abstract: HbO-Arab emerged about 2,000 years on a rare haplotype, characteristic of the Greek Pomaks. Its frequency increased as a consequence of high genetic drift within this population, and it was dispersed throughout the Mediterranean basin and Middle East with minor variations of its haplotypic pattern.
authors.forename: Vassilios
authors.initials: V
authors.lastname: Papadopoulos
authors.forename: Emmanouil
authors.initials: E
authors.lastname: Dermitzakis
authors.forename: Despina
authors.initials: D
authors.lastname: Konstantinidou
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Petridis
authors.forename: Georgios
authors.initials: G
authors.lastname: Xanthopoulidis
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Loukopoulos
mesh_terms: D005787:Gene Frequency; D040961:Genetic Drift; D014644:Genetic Variation; D006115:Greece; D006239:Haplotypes; D006455:Hemoglobins, Abnormal / Q000235:genetics*; D006801:Humans; D009154:Mutation; D012150:Polymorphism, Restriction Fragment Length; D044382:Population Groups; D011995:Recombination, Genetic
chemical_list: D006455:Hemoglobins, Abnormal; C032031:hemoglobin Arab