title: [Pleomorphic adenoma of nose and accessory nasal sinuses: a report of 15 cases].
abstract: OBJECTIVE
  To discuss the clinical characteristics and the treatment of pleomorphic adenoma of nose and accessory nasal sinuses (NPA).
  
  
  METHODS
  Fifteen cases of NPA were treated, 2 cases underwent radical maxillary sinusotomy, 2 cases nasal polypectomy, 10 cases lateral rhinotomy and 1 case maxillectomy.
  
  
  RESULTS
  No recurrence occurred in 7 cases, recurrence occurred in 6 cases, planted recurrence occurred in 1 case, malignant evolution occurred in 1 cases (carcinosarcoma) after the first operation. The 6 cases of recurrence underwent an operation for the second time, 2 cases had no recurrence, 2 cases recurred again, 2 cases became malignant (one was adenoid cystic carcinoma, the other was squamous cell carcinoma). The case who was planted recurrence underwent radiotherapy with 60 Gy and died of failure to respond to medical treatment at last.
  
  
  CONCLUSIONS
  The rate of recurrence and misdiagnosis is very high in NPA, this tumor can be malignant evolution easily after many operations. To get rid of focus completely, it is important to apply a wide range of surgical operation in the first operation, which is the key to treatment. Rapid sections-cutting for microscopic examination should be done during operation, biopsy must not be done before operation if a tumour of nose is suspected to be NPA. Prognosis of this tumour is mainly linked to recurrences in cases of incomplete resection and to possible metastasis, such as an eventual malignant evolution.
authors.affiliation: Department of Otorhinolaryngology, Haian Hospital of Nantong Medical College, Haian, 226600, China.
authors.forename: Liangjun
authors.initials: L
authors.lastname: Lu
authors.forename: Liang
authors.initials: L
authors.lastname: Zhou
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Li
authors.forename: Haitao
authors.initials: H
authors.lastname: Wu
authors.forename: Peijie
authors.initials: P
authors.lastname: He
authors.forename: Decheng
authors.initials: D
authors.lastname: Jiang
authors.forename: Zhisheng
authors.initials: Z
authors.lastname: Zhong
authors.forename: Xu
authors.initials: X
authors.lastname: Wang
mesh_terms: D008949:Adenoma, Pleomorphic / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy / Q000601:surgery; D009669:Nose Neoplasms / Q000601:surgery*; D010255:Paranasal Sinus Neoplasms / Q000601:surgery*