[Skin toxicity of sodium lauryl sulfate as evidenced in an animal model].
This study presents the toxic effects of a very known and used compound in pharmaceutical products and from cosmetic market, a detergent (surface-active) anionic. The presented data underlined the effects of an ointment base with sodium lauryl sulfate, with various concentrations of this detergent, respectively: 0.5%, 1% and 3%, in a long term utilization of this, on an animal model with Sprague Dawley rats.
Dehelean
Cristina
C
Universitatea de Medicină şi Farmacie Victor Babeş Timişoara, Facultatea de Farmacie, Disciplina de Dermatofarmacie şi Cosmetologie.
Năstase
V
V
Dragomirescu
Anca
A
Hegheş
Alina
A
Dinte
Elena
E
D000818:Animals; D023421:Models, Animal; D009824:Ointments; D051381:Rats; D017207:Rats, Sprague-Dawley; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D012967:Sodium Dodecyl Sulfate / Q000009:adverse effects*; D013501:Surface-Active Agents / Q000009:adverse effects*
D009824:Ointments; D013501:Surface-Active Agents; D012967:Sodium Dodecyl Sulfate