Ketone synthesis by intramolecular acylation of organorhodium(I) with ester.
New cyclization reactions forming cyclic ketones were developed wherein an intermediate organorhodium(I) species underwent intramolecular acylation with an ester group. A 2-norbornanone skeleton is constructed in a single operation through successive multiple carbon-carbon bond formation. The reactions ended up with generation of an alkoxyrhodium(I) species to promote the next catalytic cycle.
Miura
Tomoya
T
Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto 615-8510, Japan.
Sasaki
Taisuke
T
Nakazawa
Hiroki
H
Murakami
Masahiro
M