The cadherin superfamily and dendrite development.
Dendrite morphogenesis is a highly dynamic process that involves constant extension and retraction of branches, and stabilization of these dynamics has pivotal roles in determining the number and length of branches. The classic cadherin N-cadherin is involved in stabilization of dendritic spines and branches. Recent work in mammals by Shima et al., and earlier work in Drosophila by Gao et al. and Sweeney et al. have determined the presence of a non-classic, seven-pass transmembrane cadherin in this process.
Ye
Bing
B
Howard Hughes Medical Institute, Departments of Physiology, Biochemistry and Biophysics, University of California-San Francisco, San Francisco, CA 94143-0725, USA.
Jan
Yuh Nung
YN
D000818:Animals; D015820:Cadherins / Q000502:physiology*; D003712:Dendrites / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D009474:Neurons / Q000166:cytology / Q000502:physiology
C498477:CELSR2 protein, human; D015820:Cadherins