title: Quality of life of patients with maxillofacial defects after treatment for malignancy.
abstract: OBJECTIVE
  The purpose of the study was to investigate how cancer patients with maxillofacial defects evaluate their quality of life after prosthodontic therapy, complemented by a retrospective interview for judging the various therapy steps. The results were compared with a nontumor control group (multiple tooth extractions) and with population-based norm data.
  
  
  METHODS
  A total of 34 patients were included in the study, 17 in each group. Patients first filled in a questionnaire and then answered additional questions in a standardized interview.
  
  
  RESULTS
  At the time of investigation, tumor patients did not significantly differ from nontumor patients regarding global quality of life. However, tumor patients had significantly less favorable values regarding role functioning, speech, mouth opening, and dry mouth, as well as pain and swallowing. In comparison with the reference data of the German population, tumor patients had considerable deficits (> 20 points) regarding role functioning, dyspnea, and financial difficulties. Other deficits (> 10 points) became apparent in global quality of life, fatigue, insomnia, and appetite. When reflecting the course of disease and recovery, tumor patients rated the diagnosis as the most stressful event and reported that the family was most instrumental in the recovery process.
  
  
  CONCLUSIONS
  Patients with maxillofacial defects after treatment for malignancy suffer from numerous clearly definable quality of life-related symptoms and problems, even after prosthodontic treatment. These patients need psychologic care at the time of diagnosis to alleviate the burden of the cancer diagnosis and prepare for the demanding treatment. After completion of the prosthodontic treatment, therapy options for pain or speech problems should be offered.
authors.affiliation: Department of Preclinical and Maxillofacial Prosthodontics, Marburg School of Dental Medicine, Philipps University, Marburg, Germany.
authors.forename: Katrin
authors.initials: K
authors.lastname: Hertrampf
authors.forename: Hans J
authors.initials: HJ
authors.lastname: Wenz
authors.forename: Klaus M
authors.initials: KM
authors.lastname: Lehmann
authors.forename: Wilfried
authors.initials: W
authors.lastname: Lorenz
authors.forename: Michael
authors.initials: M
authors.lastname: Koller
mesh_terms: D000328:Adult; D000368:Aged; D001066:Appetite / Q000502:physiology; D003430:Cross-Sectional Studies; D003679:Deglutition / Q000502:physiology; D017266:Dental Prosthesis / Q000523:psychology; D004417:Dyspnea / Q000503:physiopathology; D005153:Facial Neoplasms / Q000503:physiopathology / Q000523:psychology / Q000601:surgery*; D005195:Family Relations; D005221:Fatigue / Q000503:physiopathology; D005260:Female; D006801:Humans; D007573:Jaw Neoplasms / Q000503:physiopathology / Q000523:psychology / Q000601:surgery*; D008297:Male; D008334:Mandible / Q000503:physiopathology; D008875:Middle Aged; D010149:Postoperative Pain / Q000503:physiopathology; D011788:Quality of Life; D012189:Retrospective Studies; D007319:Sleep Initiation and Maintenance Disorders / Q000503:physiopathology; D013060:Speech / Q000502:physiology; D013315:Stress, Psychological / Q000503:physiopathology; D014081:Tooth Extraction / Q000523:psychology; D014987:Xerostomia / Q000503:physiopathology