SAXS and the working protein.
In this issue of Structure, Davies et al., 2005, present shape reconstructions for the molecular motor p97 using small angle X-ray scattering (SAXS) and offer insights into how ATP consumption is coupled to cyclical domain motions. This work emphasizes the emerging potential of SAXS for visualizing the workings of biological machines in solution.
Nagar
Bhushan
B
Kuriyan
John
J
D000251:Adenosine Triphosphatases; D000818:Animals; D018797:Cell Cycle Proteins / Q000737:chemistry*; D018360:Crystallography, X-Ray; D011487:Protein Conformation; D000074405:Valosin Containing Protein; D014961:X-Ray Diffraction
D018797:Cell Cycle Proteins; D000251:Adenosine Triphosphatases; D000074405:Valosin Containing Protein