title: Intravascular ultrasound assessment of lesions with target vessel failure after sirolimus-eluting stent implantation.
abstract: Intravascular ultrasound (IVUS) evaluation was performed in 33 lesions with sirolimus-eluting stent (SES) failure: 4 thromboses, 26 in-stent restenoses (including 6 edge stenoses), 4 new stenoses >5 mm proximal to the stent, and 1 patient with no evidence of the implanted SES (presumably because of embolization). A minimum stent area <5.0 mm(2) (stent underexpansion) was observed in 67% of all SES failures (in particular, 67% of intrastent restenosis); negative remodeling was observed in 4 of 6 stent edge restenoses, and new lesions were secondary to an increase in plaque area.
authors.affiliation: Cardiovascular Research Foundation, New York, New York, USA.
authors.forename: Hideo
authors.initials: H
authors.lastname: Takebayashi
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Gary S
authors.initials: GS
authors.lastname: Mintz
authors.forename: Stéphane G
authors.initials: SG
authors.lastname: Carlier
authors.forename: Kenichi
authors.initials: K
authors.lastname: Fujii
authors.forename: Takenori
authors.initials: T
authors.lastname: Yasuda
authors.forename: Issam
authors.initials: I
authors.lastname: Moussa
authors.forename: Roxana
authors.initials: R
authors.lastname: Mehran
authors.forename: George D
authors.initials: GD
authors.lastname: Dangas
authors.forename: Michael B
authors.initials: MB
authors.lastname: Collins
authors.forename: Edward
authors.initials: E
authors.lastname: Kreps
authors.forename: Alexandra J
authors.initials: AJ
authors.lastname: Lansky
authors.forename: Gregg W
authors.initials: GW
authors.lastname: Stone
authors.forename: Martin B
authors.initials: MB
authors.lastname: Leon
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Moses
mesh_terms: D023903:Coronary Restenosis / Q000000981:diagnostic imaging*; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage*; D020123:Sirolimus / Q000008:administration & dosage*; D015607:Stents / Q000009:adverse effects*; D017211:Treatment Failure; D018084:Ultrasonography, Interventional
chemical_list: D010975:Platelet Aggregation Inhibitors; D020123:Sirolimus