Treatment of unstable angina pectoris with modified nuan gan jian--a report of 33 cases.
OBJECTIVE
To observe the effectiveness of Modified Nuan Gan Jian Jiao Nang (MNGJ [symbol: see text] Modified Liver-Warming Capsule) in treating unstable angina pectoris.


METHODS
Sixty-six eligible cases were assigned randomly into a treatment group and a control group and treated for 3 weeks.


RESULTS
MNGJ produced an effect in reducing episodes, improving the abnormal findings in electro-cardiogram (ECG) (P<0.05) significantly, and decreasing myocardial oxygen consumption (P<0.05). In addition, it could decrease the plasma TXB2 level and increase 6-keto-prostaglandin F1alpha (6-Keto-PGF1alpha) level (P<0.01).


CONCLUSIONS
MNGJ was quite effective in treating unstable angina pectoris, suggesting that the treatment of the disease could start from the liver.
He
Jingbo
J
People's Hospital of Bao'an District, Shenzhen, 518101, China.
Huang
Mianqing
M
Zhang
Qin
Q
Liao
Wanbai
W
Wang
Lijun
L
Zhang
Yuying
Y
D015121:6-Ketoprostaglandin F1 alpha / Q000097:blood; D000368:Aged; D000789:Angina, Unstable / Q000097:blood / Q000188:drug therapy*; D003937:Diagnosis, Differential; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D008517:Phytotherapy; D013929:Thromboxane B2 / Q000097:blood
D004365:Drugs, Chinese Herbal; D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha