title: Vascular graft infection in aortoiliac and aortofemoral bypass surgery: clinical presentation, diagnostic strategies and results of surgical treatment.
abstract: OBJECTIVE
  Evaluation of the prevalence, diagnostic procedures and clinical outcome of infections of aortoiliac and aortofemoral vascular grafts presented in our centre.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  All patients who underwent a surgical aortoiliac or aortofemoral revascularisation between 1991 and 2001.
  
  
  METHODS
  Evaluation of several hospital databases.
  
  
  RESULTS
  32 cases of aortoiliac and aortofemoral vascular graft infection with varied clinical presentation were found. Enteral bleeding was the first clinical manifestation in 31% of the cases, inguinal swelling, wound, or fistula in 59% and fever or sepsis in 6.3%. In 3% the cause was unknown. The vast majority (84.5%) of the infections presented three or more months after surgery (late infections). In cases of enteral bleeding, endoscopy procedures only revealed the diagnosis in 55%. Diagnostic algorithms including an abdominal CT scan appeared to have a sensitivity of 94% for establishing an accurate diagnosis. Remarkably, no specific risk factors for graft infection could be demonstrated. Furthermore, a 30-day survival of 20% or less was observed in early graft infections, whereas late infections managed with extra-anatomical bypasses appeared to have a better survival rate of up to 70%.
  
  
  CONCLUSIONS
  Endoscopy in cases of enteral bleeding and CT scanning overall were shown to be very useful for establishing the diagnosis. Clinical outcome and survival after treatment remain poor.
authors.affiliation: Department of General Internal Medicine, University Medical Centre St Radboud, Nijmegen, The Netherlands.
authors.forename: C
authors.initials: C
authors.lastname: Soetevent
authors.forename: P L
authors.initials: PL
authors.lastname: Klemm
authors.forename: A F H
authors.initials: AF
authors.lastname: Stalenhoef
authors.forename: S J H
authors.initials: SJ
authors.lastname: Bredie
mesh_terms: D000368:Aged; D001012:Aorta, Abdominal / Q000601:surgery*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D005260:Female; D005263:Femoral Artery / Q000601:surgery*; D006801:Humans; D007083:Iliac Artery / Q000601:surgery*; D008297:Male; D016459:Prosthesis-Related Infections / Q000175:diagnosis*