title: Anti-Candida activity of Brazilian medicinal plants.
abstract: Essential oils and ethanolic extracts from the leaves and/or roots of 35 medicinal plants commonly used in Brazil were screened for anti-Candida albicans activity. The oils were obtained by water-distillation using a Clevenger-type system. Essential oils from 13 plants showed anti-Candida activity, including Aloysia triphylla, Anthemis nobilis, Cymbopogon martini, Cymbopogon winterianus, Cyperus articulatus, Cyperus rotundus, Lippia alba, Mentha arvensis, Mikania glomerata, Mentha piperita, Mentha sp., Stachys byzantina, and Solidago chilensis. The ethanol extract was not effective at any of the concentrations tested. Chemical analyses showed the presence of compounds with known antimicrobial activity, including 1,8-cineole, geranial, germacrene-D, limonene, linalool, and menthol.
authors.affiliation: Research Center for Chemistry, Biology and Agriculture, State University of Campinas, P.O. Box 6171, CEP 13083-970 Campinas, SP, Brazil. mduarte@cpqba.unicamp.br
authors.forename: Marta Cristina Teixeira
authors.initials: MC
authors.lastname: Duarte
authors.forename: Glyn Mara
authors.initials: GM
authors.lastname: Figueira
authors.forename: Adilson
authors.initials: A
authors.lastname: Sartoratto
authors.forename: Vera Lúcia Garcia
authors.initials: VL
authors.lastname: Rehder
authors.forename: Camila
authors.initials: C
authors.lastname: Delarmelina
mesh_terms: D000935:Antifungal Agents / Q000302:isolation & purification* / Q000494:pharmacology / Q000627:therapeutic use; D001938:Brazil; D002176:Candida albicans / Q000187:drug effects*; D020834:Ethnopharmacology; D008519:Medicine, Traditional; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000302:isolation & purification* / Q000494:pharmacology; D010936:Plant Extracts / Q000302:isolation & purification* / Q000494:pharmacology; D018515:Plant Leaves; D010938:Plant Oils / Q000302:isolation & purification* / Q000494:pharmacology; D018517:Plant Roots; D010946:Plants, Medicinal
chemical_list: D000935:Antifungal Agents; D009822:Oils, Volatile; D010936:Plant Extracts; D010938:Plant Oils