title: Degenerative diseases of the lumbar spine. Comparison of the multiecho data image combination sequence with magnetization transfer saturation pulse versus lumbar myelography/postmyelographic computed tomography.
abstract: OBJECTIVE
  To compare a T2* weighted 2D spoiled gradient echo multiecho sequence (MEDIC) with magnetization transfer saturation pulse versus lumbar myelography and postmyelographic computed tomography (pCT).
  
  
  METHODS
  84 disk levels in 27 patients were examined. The vertebral bodies, intervertebral disks, neural foramina, cauda equina, ligamentum flavum, and narrowing of the spinal canal were investigated using an evaluation scale. In addition, the pCT and the MEDIC sequence were evaluated for assessing the narrowing of the neural foramina in a phantom study using a cadaver preparation of the lumbar spine.
  
  
  RESULTS
  A total of 28 disk herniations, 11 cases of osteophytes narrowing the spinal canal or the neural foramina, and 7 spinal canal stenoses were detected. The pCT was significantly better in visualizing the cauda equina. The MEDIC sequence was significantly superior in visualizing the extension of the ligamentum flavum. No statistical differences between either image modality were found concerning assessment of the narrowing of the neural foramina and the spinal canal, nor regarding evaluation of the vertebral disk and the vertebral body. Measurements of the phantom study showed that the MEDIC sequence did not overestimate narrowing of the neural foramina.
  
  
  CONCLUSIONS
  The T2* MEDIC sequence has proved to be as accurate as pCT in evaluating osteophytes and narrowing of the neural foramina. In doubtful standard magnetic resonance imaging findings, this means that an additional axial T2* MEDIC sequence may be of value in reaching the same accuracy as pCT.
authors.affiliation: Saarland University Clinic, Department for Neuroradiology, Homburg, Germany. ulrich.dorenbeck@uniklinik-saarland.de
authors.forename: U
authors.initials: U
authors.lastname: Dorenbeck
authors.forename: A G
authors.initials: AG
authors.lastname: Schreyer
authors.forename: I Q
authors.initials: IQ
authors.lastname: Grunwald
authors.forename: P
authors.initials: P
authors.lastname: Held
authors.forename: S
authors.initials: S
authors.lastname: Feuerbach
authors.forename: J
authors.initials: J
authors.lastname: Seitz
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009192:Myelography; D019636:Neurodegenerative Diseases / Q000150:complications / Q000000981:diagnostic imaging*; D013122:Spinal Diseases / Q000150:complications / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography