title: Distribution and characteristics of Escherichia coli clonal group A.
abstract: Among 1,102 recent Escherichia coli clinical isolates, clonal group A was identified in 17 of 20 (U.S. and non-U.S.) geographic locales, mainly among U.S. isolates (9% vs. 3%; p < 0.001) and those resistant to trimethoprim-sulfamethoxazole (10% vs. 1.7%; p < 0.001). The extensive antimicrobial resistance and virulence profiles of clonal group A may underlie its recent widespread emergence.
authors.affiliation: Infectious Diseases (111F), Minneapolis VA Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, USA. johns007@umn.edu
authors.forename: James R
authors.initials: JR
authors.lastname: Johnson
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Murray
authors.forename: Michael A
authors.initials: MA
authors.lastname: Kuskowski
authors.forename: Sören
authors.initials: S
authors.lastname: Schubert
authors.forename: Marie-Francoise
authors.initials: MF
authors.lastname: Prère
authors.forename: Bertrand
authors.initials: B
authors.lastname: Picard
authors.forename: Raul
authors.initials: R
authors.lastname: Colodner
authors.forename: Raul
authors.initials: R
authors.lastname: Raz
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D002648:Child; D021821:Communicable Diseases, Emerging / Q000453:epidemiology* / Q000382:microbiology; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000145:classification* / Q000187:drug effects / Q000235:genetics / Q000472:pathogenicity; D004927:Escherichia coli Infections / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D010802:Phylogeny; D015995:Prevalence; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology*; D014481:United States / Q000453:epidemiology; D014552:Urinary Tract Infections / Q000453:epidemiology* / Q000382:microbiology; D014774:Virulence
chemical_list: D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination