title: [Study of in vitro cytotoxic activity of cyclopentanones derivatives].
abstract: The cytotoxicity of 30 cyclopentanone derivatives was studied in vitro, in a clonogenic assay using murine leukemia L1210. Results are compared to those obtained with reference medicaments. 17 derivatives exhibit activities against L1210 cells.
authors.affiliation: Laboratoire de maladies transmissibles et de substances biologiquement actives, Faculté de Pharmacie, Monastir, Tunisie.
authors.forename: Ahlem
authors.initials: A
authors.lastname: Ben Sassi
authors.forename: Thabet
authors.initials: T
authors.lastname: Tabka
authors.forename: Pascal
authors.initials: P
authors.lastname: Gauduchon
authors.forename: Patrick
authors.initials: P
authors.lastname: Dallemagne
authors.forename: Mahjoub
authors.initials: M
authors.lastname: Aouni
mesh_terms: D000818:Animals; D003517:Cyclopentanes / Q000627:therapeutic use*; D004354:Drug Screening Assays, Antitumor; D007939:Leukemia L1210 / Q000188:drug therapy* / Q000473:pathology; D051379:Mice; D014407:Tumor Cells, Cultured
chemical_list: D003517:Cyclopentanes; C007201:cyclopentanone