Genome-wide analysis of the context-dependence of regulatory networks.
Genome-wide analytical tools are now allowing the discovery of the design rules that govern regulatory networks. Two recent studies in yeast have helped reveal the relatively small number of transcription-factor control strategies that cells employ to maximize their regulatory options using only a small number of components.
Papp
Balázs
B
Faculty of Life Sciences, University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK.
Oliver
Stephen
S
D001665:Binding Sites; D015966:Gene Expression Regulation, Fungal; D016681:Genome, Fungal; D023281:Genomics; D011401:Promoter Regions, Genetic; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism; D014157:Transcription Factors / Q000378:metabolism*
D029701:Saccharomyces cerevisiae Proteins; D014157:Transcription Factors