title: Cyclosporin A therapy in a case with hyperimmunoglobulin E and nephrotic syndrome.
abstract: We describe the beneficial effects of treatment with cyclosporin A in a 10-year-old boy with hyperimmunoglobulin E and refractory nephrotic syndrome. The patient was initially resistant to steroid therapy with prednisolone alone. Additional therapy with cyclosporin A was then prescribed, effectively reducing levels of serum immunoglobulin E and preventing flare up of nephrotic syndrome.
authors.affiliation: Department of Pediatrics, Pingtung Christian Hospital, Pingtung, Taiwan.
authors.forename: Chin-Nam
authors.initials: CN
authors.lastname: Bong
authors.forename: Shun-Chen
authors.initials: SC
authors.lastname: Huang
authors.forename: Chih-Lu
authors.initials: CL
authors.lastname: Wang
authors.forename: Po-Mai
authors.initials: PM
authors.lastname: Liu
authors.forename: Hsin-Hsu
authors.initials: HH
authors.lastname: Chen
authors.forename: Kuender D
authors.initials: KD
authors.lastname: Yang
mesh_terms: D002648:Child; D016572:Cyclosporine / Q000627:therapeutic use*; D006801:Humans; D007589:Job Syndrome / Q000188:drug therapy*; D008297:Male; D009404:Nephrotic Syndrome / Q000188:drug therapy*; D011241:Prednisone / Q000627:therapeutic use; D018417:Th1 Cells / Q000276:immunology; D018418:Th2 Cells / Q000276:immunology
chemical_list: D016572:Cyclosporine; D011241:Prednisone