title: Thrombus formation on an atrial septal defect closure device.
abstract: Atrial septal defects (ASDs) are the most prevalent form of congenital heart disease presenting after childhood. Percutaneous closure has become a safe and effective strategy for managing adults with secundum-type ASDs. Reports on complications are rare. The present report discusses a case of rapid formation of a large thrombus on an ASD transcatheter closure device. The case highlights the importance of transesophageal echocardiography during the procedure and supports the role of periprocedural anticoagulation in transcatheter ASD closures.
authors.affiliation: Department of Cardiology, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia. aclarke@avdha.nshealth.ca
authors.forename: Adam C
authors.initials: AC
authors.lastname: Clarke
authors.forename: Kristine J
authors.initials: KJ
authors.lastname: Hirsch
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Kells
authors.forename: Jonathan
authors.initials: J
authors.lastname: Howlett
mesh_terms: D000368:Aged; D006328:Cardiac Catheterization / Q000379:methods*; D017548:Echocardiography, Transesophageal; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D005500:Follow-Up Studies; D006344:Heart Septal Defects, Atrial / Q000000981:diagnostic imaging* / Q000601:surgery*; D006801:Humans; D019060:Minimally Invasive Surgical Procedures / Q000009:adverse effects / Q000379:methods; D019919:Prosthesis Implantation / Q000009:adverse effects* / Q000379:methods; D018570:Risk Assessment; D012720:Severity of Illness Index; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents