Mutations in the human BOULE gene are not a major cause of impaired spermatogenesis.
Mutation screening of the BOULE gene in 156 men with azoospermia or severe oligozoospermia revealed no relevant mutations; thus, mutations in BOULE can be eliminated as a major cause of impaired spermatogenesis.
Westerveld
G Henrike
GH
Center for Reproductive Medicine, Department of Obstetrics and Gynaecology, Academic Medical Center, Meibergdreef 9, H4-205, 1105 AZ Amsterdam, The Netherlands. g.h.westerveld@amc.uva.nl
Repping
Sjoerd
S
Leschot
Nico J
NJ
van der Veen
Fulco
F
Lombardi
M Paola
MP
D005820:Genetic Testing; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D008297:Male; D020125:Mutation, Missense; D009845:Oligospermia / Q000235:genetics; D016601:RNA-Binding Proteins / Q000235:genetics*; D013091:Spermatogenesis / Q000235:genetics*
C481351:BOLL protein, human; D016601:RNA-Binding Proteins