title: Hepatosplenic T-cell lymphoma in an adolescent patient after immunomodulator and biologic therapy for Crohn disease.
authors.affiliation: Division of Gastroenterology and Nutrition, The Children's Hospital of Philadelphia, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA. thayu@email.chop.edu
authors.forename: Meena
authors.initials: M
authors.lastname: Thayu
authors.forename: Jonathan E
authors.initials: JE
authors.lastname: Markowitz
authors.forename: Petar
authors.initials: P
authors.lastname: Mamula
authors.forename: Pierre A
authors.initials: PA
authors.lastname: Russo
authors.forename: William I
authors.initials: WI
authors.lastname: Muinos
authors.forename: Robert N
authors.initials: RN
authors.lastname: Baldassano
mesh_terms: D000293:Adolescent; D000911:Antibodies, Monoclonal / Q000009:adverse effects* / Q000627:therapeutic use; D003424:Crohn Disease / Q000150:complications* / Q000188:drug therapy; D017809:Fatal Outcome; D005260:Female; D005765:Gastrointestinal Agents / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D000069285:Infliximab; D008113:Liver Neoplasms / Q000175:diagnosis / Q000209:etiology*; D016399:Lymphoma, T-Cell / Q000175:diagnosis / Q000209:etiology*; D015122:Mercaptopurine / Q000009:adverse effects* / Q000627:therapeutic use; D013160:Splenic Neoplasms / Q000175:diagnosis / Q000209:etiology*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
chemical_list: D000911:Antibodies, Monoclonal; D005765:Gastrointestinal Agents; D007166:Immunosuppressive Agents; D014409:Tumor Necrosis Factor-alpha; D000069285:Infliximab; D015122:Mercaptopurine