title: Modelling the VO2 kinetic response to heavy intensity exercise in children.
abstract: The purpose of this study was to apply a series of mathematical models in order to investigate the nature of the kinetic response to heavy intensity exercise with children and identify a suitable model with which to estimate parameters of the response. Sixty two children (35 male, 27 female aged 10-15 years) completed four transitions from baseline pedalling to 40% of the difference between their previously determined anaerobic threshold and peak VO2 on an electronically braked cycle ergometer. Initially three models were fitted to the averaged response profiles following the end of phase 1. and their residuals compared; 1, a single exponential with a delay term; 2, an exponential and linear term with independent delays; and 3, a double exponential with independent delays. Up to 95% of the response profiles were better fitted by either model 2 or 3 (p < 0.05), and model 3 was a statistically better fit (p < 0.05) than model 2 in 77% of cases. Residual inspection confirmed the superior fit by model 3. A fourth model which consisted of a single exponential with a delay term was fitted within the phase 2 fitting window. Estimated parameters (A1 and tau1), using model 4 were not significantly different from model 3, and model 4 was identified as the model of choice due to the wide confidence intervals in tau2 and A2 using model 3. It was concluded that the nature of the response to heavy intensity exercise in children is similar to that previously reported with adults and that the response should be modelled accordingly.
authors.affiliation: Children's Health and Exercise Research Centre, University of Exeter, Exeter, UK. S.G.Fawkner@hw.ac.uk
authors.forename: Samantha G
authors.initials: SG
authors.lastname: Fawkner
authors.forename: Neil
authors.initials: N
authors.lastname: Armstrong
mesh_terms: D000293:Adolescent; D002648:Child; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008954:Models, Biological; D010101:Oxygen Consumption; D011659:Pulmonary Gas Exchange