From plants to man: the GPCR "tree of life".
This Perspective focuses on the article by Fredriksson and Schiöth in the May [corrected] 2005 issue of Molecular Pharmacology. Their article describes the expansion and evolution of G protein-coupled receptors during the nematode-to-chordate split.
Perez
Dianne M
DM
Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. perezd@ccf.org
D000818:Animals; D006801:Humans; D010802:Phylogeny; D010944:Plants / Q000235:genetics*; D043562:Receptors, G-Protein-Coupled / Q000235:genetics*
D043562:Receptors, G-Protein-Coupled