title: Design and synthesis of a new class of arginine analogues with an improved anion binding site in the side chain.
abstract: Replacing the guanidinium group in arginine (1) by a guanidiniocarbonyl pyrrole moiety provides a new class of artificial amino acids (2), that can be used as building blocks in standard solid phase peptide synthesis.
authors.affiliation: Institut für Organische Chemie, Universität Würzburg, Am Hubland, 97074, Würzburg, Germany. schmuck@chemie.uni-wuerzburg.de
authors.forename: Carsten
authors.initials: C
authors.lastname: Schmuck
authors.forename: Lars
authors.initials: L
authors.lastname: Geiger
mesh_terms: D000838:Anions / Q000737:chemistry*; D001120:Arginine / Q000031:analogs & derivatives / Q000737:chemistry*; D001665:Binding Sites; D015195:Drug Design; D019791:Guanidine / Q000031:analogs & derivatives* / Q000737:chemistry; D011758:Pyrroles / Q000737:chemistry
chemical_list: D000838:Anions; D011758:Pyrroles; D001120:Arginine; D019791:Guanidine