title: Interaction of dopamine and acetylcholine with an amphiphilic resorcinarene receptor in aqueous micelle system.
abstract: The molecular recognition of neurotransmitters, dopamine and acetylcholine with an amphiphilic resorcinarene receptor was investigated in an aqueous sodium dodecylsulfate (SDS) micelle system by 1H NMR measurements. The interaction distances of these neurotransmitters from the hydrophilic cavity of the amphiphilic receptor were estimated based on the calculation of the ring current shift using the atomic coordinates obtained from molecular dynamics calculation.
authors.affiliation: Division of Biological Sciences, Graduate School of Science, Hokkaido University, Sapporo 060-0810, Japan. demura@sci.hokudaia.ac.jp
authors.forename: Makoto
authors.initials: M
authors.lastname: Demura
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Yoshida
authors.forename: Takatsugu
authors.initials: T
authors.lastname: Hirokawa
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Kumaki
authors.forename: Tomoyasu
authors.initials: T
authors.lastname: Aizawa
authors.forename: Katsutoshi
authors.initials: K
authors.lastname: Nitta
authors.forename: Isván
authors.initials: I
authors.lastname: Bitter
authors.forename: Klára
authors.initials: K
authors.lastname: Tóth
mesh_terms: D000109:Acetylcholine / Q000737:chemistry*; D047250:Calixarenes; D004298:Dopamine / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000592:standards; D008823:Micelles; D008958:Models, Molecular; D015394:Molecular Structure; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000737:chemistry*; D012015:Reference Standards; D012967:Sodium Dodecyl Sulfate / Q000737:chemistry; D013329:Structure-Activity Relationship; D014867:Water / Q000737:chemistry
chemical_list: D008823:Micelles; C466160:resorcinarene; D014867:Water; D047250:Calixarenes; D012967:Sodium Dodecyl Sulfate; D010649:Phenylalanine; D000109:Acetylcholine; D004298:Dopamine