title: [The pathogen spectrum of acute bacterial rhinitis/sinusitis and antibiotic resistance].
abstract: OBJECTIVE
  Bacterial rhinosinusitis is one of the most frequent indications for an antibiotic therapy. The objective of this study was the analysis of the current pathogen spectrum and its antimicrobial susceptibility.
  
  
  METHODS
  Between 1999 and 2004, 188 specimens obtained from 170 patients with acute, purulent rhinosinusitis were analysed.
  
  
  RESULTS
  A total of 217 pathogens were isolated. The most common isolates were Streptococcus pneumoniae (33%), Haemophilus influenzae (27%), Staphylococcus aureus (13%), Moraxella catarrhalis (11%) and streptococci (7%). S. pneumoniae, H. influenzae and M. catarrhalis were the predominant pathogens in children. S. pneumoniae, S. aureus and streptococci, however, dominated in specimens from adults.
  
  
  CONCLUSIONS
  Based on these results, adults should be treated with an aminopenicillin with beta-lactamase inhibitor or a cephalosporin of the second generation. For children , however, the first line antibiotic is an aminopenicillin.
authors.affiliation: Klinik für Hals-, Nasen-, Ohrenheilkunde/Plastische Operationen des Universitätsklinikums Leipzig. ulrich.fickweiler@medizin.uni-leipzig.de
authors.forename: U
authors.initials: U
authors.lastname: Fickweiler
authors.forename: K
authors.initials: K
authors.lastname: Fickweiler
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000145:classification / Q000627:therapeutic use; D001419:Bacteria / Q000302:isolation & purification; D001424:Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology*; D015984:Causality; D002648:Child; D002675:Child, Preschool; D015169:Colony Count, Microbial / Q000706:statistics & numerical data*; D015897:Comorbidity; D004351:Drug Resistance; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D012220:Rhinitis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology*; D012852:Sinusitis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents