Ribbon synapses: anchors away for a fishy tale.
Genetic screens in flies and worms have long been a powerful way of identifying proteins that regulate synaptic transmission. A recent study of ribbon synapses in the retina of zebrafish is an excellent example of how this approach can now be applied to a vertebrate species.
Lagnado
Leon
L
MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK.
D000818:Animals; D005089:Exocytosis / Q000502:physiology; D006309:Hearing / Q000502:physiology; D009154:Mutation / Q000235:genetics; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000502:physiology; D009475:Neurons, Afferent / Q000166:cytology* / Q000502:physiology; D010744:Phosphoric Monoester Hydrolases / Q000235:genetics / Q000502:physiology; D012160:Retina / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D013569:Synapses / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology*; D014785:Vision, Ocular / Q000502:physiology; D015027:Zebrafish
D009419:Nerve Tissue Proteins; C097702:synaptojanin; D010744:Phosphoric Monoester Hydrolases