[Histopathology study of supraglottic carcinoma with different vocal cord movement].
OBJECTIVE
To explore the histopathology characteristics of supraglottic carcinoma with different vocal cord movement, and to find the theory basis for partial laryngectomy.


METHODS
Eighty-four cases of supraglottic laryngeal carcinoma specimen were imbedded in collodion, and then make whole-organ serial section for HE staining, observing under light microscope.


RESULTS
For the vocal cord fixation, the rate of invasion to arytenoids, to infra-paraglottic space and to both arytenoids and infra-paraglottic space was 46.2%, 15.4%, and 38.5%, respectively; For the vocal cord limitation, the rate of invasion to arytenoids, to infra-paraglottic space and to both arytenoids and infra-paraglottic space was 46.7%, 6.7%, and 13.3%, respectively; For the vocal cord with good movement, no cases occurred for the invasion to the infra-paraglottic space or arytenoids. The difference was significant between them (P<0.05). There was close relationship between the tumor invasion to infra-paraglottic space with to the ventricle of larynx: for the vocal cord limitation and fixation, the ratio of the tumor invading the infra-paraglottic space to the ventricle of larynx is 40.0% and 73.7%, respectively, the difference was significant between them (P<0.05).


CONCLUSIONS
The invasion of supra-glottic carcinoma to the arytenoids or infra-paraglottic space is the main cause of the vocal cord limitation and fixation. We can do the operation of partial laryngectomy more precisely by observing the movement of the vocal cord and the invasion to laryngeal ventricle.
Bai
Weiliang
W
Department of Otolaryngology, the Second Clinical Hospital of China Medical University, Shenyang, 110004, China.
Ren
Zhong
Z
Pan
Zimin
Z
Guan
Chao
C
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D005260:Female; D005931:Glottis / Q000473:pathology / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D014827:Vocal Cords / Q000473:pathology / Q000503:physiopathology*