Outbreak of larval Echinococcus multilocularis infection in Japanese monkey (Macaca fuscata) in a zoo, Hokkaido: western blotting patterns in the infected monkeys.
A high prevalence of larval Echinococcus multilocularis (Em) infection was found in zoo primates in Hokkaido, Japan. In October 1997, a Japanese monkey (Macaca fuscata) died and histopathologically diagnosed as alveolar hydatidosis. Serum samples were collected from the remaining Japanese monkeys and examined for antibodies against Em by enzyme-linked immunosorbent assay and western blotting. Serological tests showed 12 more animals of the remaining 57 monkeys were possibly infected. Ultrasonography revealed that nine of these 12 animals had a cystic lesion in the liver. The band patterns of western blotting in the monkeys were very similar to those in human.
Sato
Chiaki
C
Hokkaido Institute of Public Health, Kita, Nishi, Kita-ku, Sapporo, Japan.
Kawase
Shiro
S
Yano
Shoki
S
Nagano
Hideki
H
Fujimoto
Satoshi
S
Kobayashi
Nobuyuki
N
Miyahara
Kazuro
K
Yamada
Kazutaka
K
Sato
Motoyoshi
M
Kobayashi
Yoshiyasu
Y
D000818:Animals; D000836:Animals, Zoo / Q000469:parasitology*; D000909:Antibodies, Helminth / Q000097:blood; D015153:Blotting, Western / Q000662:veterinary; D004196:Disease Outbreaks / Q000662:veterinary*; D004444:Echinococcosis, Hepatic / Q000453:epidemiology / Q000662:veterinary*; D048210:Echinococcus multilocularis; D007564:Japan / Q000453:epidemiology; D008099:Liver / Q000473:pathology; D008251:Macaca / Q000469:parasitology*; D008992:Monkey Diseases / Q000453:epidemiology / Q000469:parasitology*
D000909:Antibodies, Helminth