title: Paget's disease: a case in point.
abstract: Paget's disease (PD) is the second most common bone disease in older adults, yet many clinicians are unfamiliar with it and may not consider it a diagnostic possibility. This article uses a case study to introduce the topic of Paget's disease. The definition, incidence, and etiology of PD is addressed. Normal bone physiology is defined in contrast to the pathophysiology of PD. Patient history, laboratory tests, and imaging studies are summarized with regard to the diagnosis of PD. Treatment options are discussed including pharmacologic management and prognosis. The article concludes with implications for nursing care of the patient with PD.
authors.affiliation: Armstrong Atlantic State University, Savannah, GA, USA.
authors.forename: Anita S
authors.initials: AS
authors.lastname: Nivens
mesh_terms: D000359:Aftercare / Q000379:methods; D000469:Alkaline Phosphatase / Q000097:blood; D000596:Amino Acids / Q000652:urine; D002118:Calcium / Q000652:urine; D002908:Chronic Disease; D003094:Collagen / Q000652:urine; D024042:Collagen Type I; D003937:Diagnosis, Differential; D004164:Diphosphonates / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D006909:Hydroxyproline / Q000652:urine; D015994:Incidence; D008487:Medical History Taking; D024802:Nurse's Role; D010001:Osteitis Deformans / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000378:metabolism / Q000628:therapy*; D015675:Osteocalcin / Q000097:blood; D010012:Osteogenesis / Q000187:drug effects / Q000502:physiology; D010455:Peptides / Q000652:urine; D011379:Prognosis; D011788:Quality of Life; D012017:Referral and Consultation
chemical_list: D000596:Amino Acids; D024042:Collagen Type I; D004164:Diphosphonates; D010455:Peptides; C052929:collagen type I trimeric cross-linked peptide; D015675:Osteocalcin; C036020:deoxypyridinoline; D003094:Collagen; D000469:Alkaline Phosphatase; D006909:Hydroxyproline; D002118:Calcium