[Study of in vitro cytotoxic activity of cyclopentanones derivatives].
The cytotoxicity of 30 cyclopentanone derivatives was studied in vitro, in a clonogenic assay using murine leukemia L1210. Results are compared to those obtained with reference medicaments. 17 derivatives exhibit activities against L1210 cells.
Ben Sassi
Ahlem
A
Laboratoire de maladies transmissibles et de substances biologiquement actives, Faculté de Pharmacie, Monastir, Tunisie.
Tabka
Thabet
T
Gauduchon
Pascal
P
Dallemagne
Patrick
P
Aouni
Mahjoub
M
D000818:Animals; D003517:Cyclopentanes / Q000627:therapeutic use*; D004354:Drug Screening Assays, Antitumor; D007939:Leukemia L1210 / Q000188:drug therapy* / Q000473:pathology; D051379:Mice; D014407:Tumor Cells, Cultured
D003517:Cyclopentanes; C007201:cyclopentanone