Regeneration and transdetermination: new tricks from old cells.
In this issue of Cell, Sustar and Schubiger (2005) address a longstanding question in regeneration biology: How is pluripotency achieved during regeneration? The authors have examined the cell cycle and growth characteristics of multipotent regenerating and transdetermining Drosophila cells and come up with some surprising findings.
Johnston
Laura A
LA
Department of Genetics & Development, Columbia University College of Physicians & Surgeons, New York, NY 10032, USA.
D000818:Animals; D002453:Cell Cycle / Q000502:physiology; D002454:Cell Differentiation / Q000502:physiology; D019070:Cell Lineage / Q000502:physiology; D004331:Drosophila melanogaster / Q000166:cytology / Q000502:physiology; D004847:Epithelial Cells / Q000502:physiology; D005121:Extremities / Q000254:growth & development; D018507:Gene Expression Regulation, Developmental / Q000502:physiology; D039904:Pluripotent Stem Cells / Q000502:physiology; D012038:Regeneration / Q000502:physiology