[Studies on the preparation technology of beta-cyclodextrin inclusion compound for chuanxiong volatile oil extracted with CO2 supercritical fluid].
OBJECTIVE
To explore the preparation technology of beta-cyclodextrin inclusion compound for chuanxiong volatile oil.


METHODS
Orthogonal test was used to evaluate the influence of the 4 factors, including the proportion of volatile oil to beta-cyclodextrin, the mode of mixing, inclusion temperature and mixing time.


RESULTS
The best inclusion condition is the proportion of volatile oil to beta-cyclodextrin 1:9, the mode of mixing grinding, inclusion temperature 60 degrees C and inclusion time 90 min.


CONCLUSIONS
The best inclusion technology of chuanxiong volatile oil is confirmed.
Zhang
Ai-jun
AJ
Sichuan Institute of Chinese Materia Medica, Chengdu 610041, China.
Zhu
Ning
N
Yang
An-dong
AD
D002245:Carbon Dioxide; D025924:Chromatography, Supercritical Fluid; D004337:Drug Carriers; D030004:Ligusticum / Q000737:chemistry*; D009822:Oils, Volatile / Q000008:administration & dosage* / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D013997:Time Factors; D047392:beta-Cyclodextrins
D004337:Drug Carriers; D009822:Oils, Volatile; D047392:beta-Cyclodextrins; D002245:Carbon Dioxide