title: Simultaneous hepatic artery and portal vein thrombosis after living donor liver transplantation.
abstract: Simultaneous hepatic artery and portal vein thrombosis rarely occurs after liver transplantation. The etiology is unknown. Of 213 patients (72 children and 141 adults) that underwent living donor liver transplantation (LDLT) from January 1996 to March 2003, 4 (2%) developed simultaneous thrombosis at 3 hours to 7 days (median, 4 days) after the operation. Emergent thrombectomy was performed in three patients; the remaining patient was registered in the Japan organ transplant network. All of the patients died due to hepatic failure (range, 18 hours to 6 days after the diagnosis; median, 2 days). Portal vein, hepatic artery, and hepatic vein velocity in the liver graft were measured every 12 hours by Doppler ultrasonography for 2 weeks after liver transplantation. These parameters were stable until just before the simultaneous thrombosis. These findings indicate that protocol Doppler ultrasonography can diagnose, but not predict, this fatal complication.
authors.affiliation: Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Kaneko
authors.forename: Y
authors.initials: Y
authors.lastname: Sugawara
authors.forename: J
authors.initials: J
authors.lastname: Togashi
authors.forename: Y
authors.initials: Y
authors.lastname: Kishi
authors.forename: N
authors.initials: N
authors.lastname: Akamatsu
authors.forename: M
authors.initials: M
authors.lastname: Makuuchi
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006499:Hepatic Artery / Q000473:pathology*; D006801:Humans; D007223:Infant; D016031:Liver Transplantation / Q000009:adverse effects*; D019520:Living Donors; D008297:Male; D011169:Portal Vein / Q000473:pathology*; D011183:Postoperative Complications / Q000453:epidemiology; D013927:Thrombosis / Q000453:epidemiology* / Q000601:surgery