title: [Effect of Spatholobus suberectus on the bone marrow cells and related cytokines of mice].
abstract: OBJECTIVE
  To study the effect of Spatholobus suberectus on proliferation and the hematonic mechanism.
  
  
  METHODS
  The techniques of culture of hematopoietic cell and hematopoietic growth factor (HGF) assay were used.
  
  
  RESULTS
  Spatholobus suberectus could obviously promote the proliferation of bone marrow cells in healthy and anaemic mice. The culture media of spleen cell, macrophage, lung and skeletal muscle treated with S. suberectus had much stronger stimulating effects on hematopoietic cells.
  
  
  CONCLUSIONS
  S. suberectus may enhance hematopoiesis by directly or indirectly stimulating stroma cell in hematopoietic inductive microenvironment and muscle tissue to secrete some HGF (Epo, GM-CSF, IL, and MK-CSF). This is one of the biological mechanisms for hematonic effect of S. suberectus.
authors.affiliation: Sichuan University, Chengdu 610064, China.
authors.forename: Dong-hui
authors.initials: DH
authors.lastname: Chen
authors.forename: Xia
authors.initials: X
authors.lastname: Luo
authors.forename: Meng-yao
authors.initials: MY
authors.lastname: Yu
authors.forename: Yi-qing
authors.initials: YQ
authors.lastname: Zhao
authors.forename: Yao-feng
authors.initials: YF
authors.lastname: Cheng
authors.forename: Zhi-rong
authors.initials: ZR
authors.lastname: Yang
mesh_terms: D000740:Anemia / Q000473:pathology; D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology*; D049109:Cell Proliferation / Q000187:drug effects; D003115:Colony-Stimulating Factors / Q000378:metabolism*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D007887:Fabaceae / Q000737:chemistry; D005260:Female; D008297:Male; D051379:Mice; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry
chemical_list: D003115:Colony-Stimulating Factors; D004365:Drugs, Chinese Herbal