High protein diet mimics hypertyrosinemia in newborn infants.
Tyrosinemia resulting from administration of protein-dense infant diets was detected by newborn screening in two infants. Change of formula resulted in rapid resolution of the hypertyrosinemia. These cases identify nonstandard infant diets as a benign and reversible cause of tyrosinemia and a potential cause of positive newborn phenylketonuria screening.
Techakittiroj
Chulaluck
C
Hayward Genetics Center and the Department of Pediatrics, Tulane University School of Medicine, New Orleans, Louisiana 70112, USA.
Cunningham
Amy
A
Hooper
Pleasant F
PF
Andersson
Hans C
HC
Thoene
Jess
J
D003937:Diagnosis, Differential; D004035:Diet Therapy; D004044:Dietary Proteins / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007225:Infant Food / Q000009:adverse effects; D007231:Infant, Newborn; D008297:Male; D010649:Phenylalanine / Q000097:blood; D010661:Phenylketonurias / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D016896:Treatment Outcome; D014443:Tyrosine / Q000097:blood; D020176:Tyrosinemias / Q000209:etiology* / Q000628:therapy
D004044:Dietary Proteins; D014443:Tyrosine; D010649:Phenylalanine