Reduced data acquisition time in multi-dimensional NMR spectroscopy using multiple-coil probes.
A new hardware-based approach is presented to reduce data acquisition times in multi-dimensional NMR spectroscopy using a multiple-coil probe. Using a four-coil setup, two-dimensional COSY and TOCSY spectra were acquired in one-quarter the time of conventional spectra by simultaneous acquisition of different effective t1 evolution times for each coil. Data processing consists of simple phase-shifting and intensity normalization of the individual data sets, and results in spectra almost identical to those acquired in a conventional manner. This method can potentially be integrated with other new data acquisition and processing schemes for further increases in data acquisition speed.
Wang
Han
H
Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Ciobanu
Luisa
L
Webb
Andrew
A
D002738:Chloroquine / Q000737:chemistry*; D004867:Equipment Design; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation*; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D013995:Time
D002738:Chloroquine