title: New four-component Ugi-type reaction. Synthesis of heterocyclic structures containing a pyrrolo[1,2-a][1,4]diazepine fragment.
abstract: [reaction: see text] We present a convenient synthesis of novel heterocyclic structures containing pyrrolo[1,2-a][1,4]diazepine fragment using a novel modification of four-component Ugi condensation. We demonstrate the usefulness and versatility of the developed approach for the synthesis of variously substituted compounds and discuss the scope and limitations of the chemistry involved.
authors.affiliation: ChemDiv, Inc., 11558 Sorrento Valley Rd., Suite 5, San Diego, California 92121, USA.
authors.forename: Alexey P
authors.initials: AP
authors.lastname: Ilyn
authors.forename: Andrey S
authors.initials: AS
authors.lastname: Trifilenkov
authors.forename: Julia A
authors.initials: JA
authors.lastname: Kuzovkova
authors.forename: Sergey A
authors.initials: SA
authors.lastname: Kutepov
authors.forename: Alexandre V
authors.initials: AV
authors.lastname: Nikitin
authors.forename: Alexandre V
authors.initials: AV
authors.lastname: Ivachtchenko
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry; D001569:Benzodiazepines / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000970:Antineoplastic Agents; D001569:Benzodiazepines