title: Metabolic syndrome and other factors associated with increased risk of diabetes.
abstract: The prevalence of diabetes has increased dramatically in the last 3 decades. Metabolic syndrome is a strong risk factor for incident diabetes. Among components of metabolic syndrome, obesity and abnormal carbohydrate metabolism are the most significant predictors. Primary care physicians should identify patients at risk and monitor their fasting glucose and/or postprandial glucose to enable timely diagnosis of diabetes and appropriate interventions. Lifestyle interventions that help reduce body weight and pharmacologic interventions that address insulin resistance and/or postprandial glycemia may help prevent diabetes. Intensive cardiovascular risk factor management should be an integral component of any diabetes prevention plan.
authors.affiliation: David Geffen School of Medicine at UCLA, Los Angeles, California, USA. dstreja@ucla.edu
authors.forename: Dan
authors.initials: D
authors.lastname: Streja
mesh_terms: D000959:Antihypertensive Agents / Q000009:adverse effects; D014150:Antipsychotic Agents / Q000009:adverse effects; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D008019:Life Style; D024821:Metabolic Syndrome / Q000453:epidemiology / Q000503:physiopathology*; D009765:Obesity / Q000209:etiology / Q000517:prevention & control; D011320:Primary Health Care; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors
chemical_list: D000959:Antihypertensive Agents; D014150:Antipsychotic Agents