title: [Survival and prognostic factors of non small cell lung cancer: analytic review of 211 cases].
abstract: Prognostic factors have a pivotal role in clinical oncology. They are helpful in the selection of treatment, provide insights into the disease process and the therapeutic response. The number of possibly useful prognostic factors in the lung cancer is large. This study attempts to observe the survival of non small cell lung cancer (NSCLC) and to find prognostic factors and other variables potentially associated with outcome of lung cancer. It's a retrospective study based on 211 patients with NSCLC. Median survival was 6 months with 95% confidence interval: [4.2 - 7.8]. Overall 3 and 5 year survival were respectively 8.3% and 5.2%. Various Prognostic factors have been identified through univariate (Kaplan-Meier) then multivariate (Cox) analyses. In addition to the clinical factors such as age, disease extent and performance status, other variables were found of significant prognostic value, like pretherapeutic leukocyte level. Survival was significantly improved with surgery, radiation and also with chemotherapy, mainly in advanced stage (IIIB and IV).
authors.affiliation: Service de Pneumologie et d'Allergologie, Hôpital Universitaire Fattouma Bourguiba de Monastir.
authors.forename: Mohamed H
authors.initials: MH
authors.lastname: Battikh
authors.forename: Mohamed M
authors.initials: MM
authors.lastname: Ben Sayah
authors.forename: Samah
authors.initials: S
authors.lastname: Joobeur
authors.forename: Naceur
authors.initials: N
authors.lastname: Rouetbi
authors.forename: Kamel
authors.initials: K
authors.lastname: Ben Salem
authors.forename: Monia
authors.initials: M
authors.lastname: Daami
authors.forename: Anis
authors.initials: A
authors.lastname: Maatallah
authors.forename: Wahid
authors.initials: W
authors.lastname: Raham
authors.forename: Chiraz
authors.initials: C
authors.lastname: Farhat
authors.forename: Ali
authors.initials: A
authors.lastname: El Kamel
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000367:Age Factors; D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000175:diagnosis / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome