Validation of a screening instrument to identify persons for exclusion from smallpox vaccination.
Adults must be screened for atopic dermatitis and other contraindications before smallpox vaccination. We validated the sensitivity of a self-administered Centers for Disease Control and Prevention (Atlanta, GA) screening questionnaire completed by 174 hospital workers, with the workers' medical records as the reference standard. The questionnaire failed to identify one-third of the subjects who had a contraindication, although the incidence of serious adverse events has been low among vaccinees. Further assessment of screening procedures is needed if the administration of smallpox vaccine becomes more widespread in the future.
Belongia
Edward A
EA
Marshfield Clinic Research Foundation, Marshfield, Wisconsin 54449, USA. belongia.edward@mcrf.mfldclin.edu
Naleway
Allison
A
Kieke
Burney
B
Qutaishat
Salah
S
Casey
Christine
C
Shay
David K
DK
Chen
Robert T
RT
D000328:Adult; D000368:Aged; D002487:Centers for Disease Control and Prevention, U.S.; D002648:Child; D003876:Dermatitis, Atopic / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D010564:Personnel, Hospital; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D012899:Smallpox / Q000517:prevention & control*; D012900:Smallpox Vaccine / Q000008:administration & dosage* / Q000009:adverse effects*; D011795:Surveys and Questionnaires; D014481:United States; D014611:Vaccination
D012900:Smallpox Vaccine