Bias explorer: measurements of compositional bias in EMBL and GenBank sequence files.
A Windows application for compositional analysis of sequenced genomes (EMBL or GenBank flat files) is available as freeware. The application allows the user to quantify word bias using Markov chain analysis and it allows the user to generate sliding window data for GC-skew, AT-skew, purine excess, keto excess and discrete word counts. The mathematical routines reside in a dynamic link library (DLL), which can be used independently by other applications. The software is available for download at http://www.dfuni.dk/~anfu/Bioinformatics/Main.htm.
Fuglsang
Anders
A
Danish University of Pharmaceutical Sciences, Institute of Pharmacology, 2 Universitetsparken, DK-2100, Copenhagen Ø, Denmark. anfu@dfuni.dk
D015982:Bias; D030541:Databases, Genetic; D030561:Databases, Nucleic Acid; D023281:Genomics; D016247:Information Storage and Retrieval / Q000379:methods*; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D014584:User-Computer Interface