title: [Therapeutic management and clinical course of severe caustic oesophageal burns in children treated with methyl-prednisolone. Experience at a digestive endoscopic unit].
abstract: We reviewed the case histories of 28 children seen at children hospital from 31 December 1991 to 31 December 2001. These children has second and third degree oesophageal burns and they were treated by systemic Methylprednisolone (1000mg/1, 73/m2 SC). We divided the 26 children in four groups according to the time we began the steroids (before or beyond the 24th hours of the accident and according the number of steroids's bolus (less or more than 21 bolus). We analysed the number and the treatment of stricture in each group. High doses of methyl prednisolone seem to decrease the risk of oesophageal stricture. We found no difference between the children treated before the 24th hours and those treated after the 24 hours and those treated with less than 21 bolus and those with more than 21 bolus.
authors.affiliation: Service de Médecine Infantile C, Hôpital d'Enfants de Tunis.
authors.forename: Sonia
authors.initials: S
authors.lastname: Mazigh Mrad
authors.forename: Samir
authors.initials: S
authors.lastname: Boukthir
authors.forename: L
authors.initials: L
authors.lastname: Sfaihi
authors.forename: I
authors.initials: I
authors.lastname: Fetni
authors.forename: Ali
authors.initials: A
authors.lastname: Dabbabi
authors.forename: Bechir
authors.initials: B
authors.lastname: Zouari
authors.forename: Sihem
authors.initials: S
authors.lastname: Barsaoui
mesh_terms: D002057:Burns, Chemical / Q000188:drug therapy*; D002424:Caustics / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D004940:Esophageal Stenosis / Q000139:chemically induced* / Q000188:drug therapy*; D004947:Esophagus / Q000293:injuries*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D015601:Injury Severity Score; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use*
chemical_list: D002424:Caustics; D005938:Glucocorticoids; D008775:Methylprednisolone