HbO-Arab mutation originated in the Pomak population of Greek Thrace.
HbO-Arab emerged about 2,000 years on a rare haplotype, characteristic of the Greek Pomaks. Its frequency increased as a consequence of high genetic drift within this population, and it was dispersed throughout the Mediterranean basin and Middle East with minor variations of its haplotypic pattern.
Papadopoulos
Vassilios
V
Dermitzakis
Emmanouil
E
Konstantinidou
Despina
D
Petridis
Dimitrios
D
Xanthopoulidis
Georgios
G
Loukopoulos
Dimitrios
D
D005787:Gene Frequency; D040961:Genetic Drift; D014644:Genetic Variation; D006115:Greece; D006239:Haplotypes; D006455:Hemoglobins, Abnormal / Q000235:genetics*; D006801:Humans; D009154:Mutation; D012150:Polymorphism, Restriction Fragment Length; D044382:Population Groups; D011995:Recombination, Genetic
D006455:Hemoglobins, Abnormal; C032031:hemoglobin Arab