Specificity of odorant-evoked inhibition in lobster olfactory receptor neurons.
Lobster olfactory receptor neurons, like those of many animals, use two modes of olfactory signaling, excitation and inhibition to code olfactory information. Inhibition appears to act through two distinct ionic mechanisms. Here we show that neither ionic mechanism is odor-specific, providing further support for the emerging understanding that there are no inhibitory odorants per se, but rather that the action of a particular odorant is inherent in the olfactory receptor cell on which an odorant acts.
Doolin
Richard E
RE
Whitney Laboratory, University of Florida, 9505 Ocean Shore Blvd, St Augustine, FL 32080, USA.
Ache
Barry W
BW
D000818:Animals; D001120:Arginine / Q000494:pharmacology*; D003545:Cysteine / Q000494:pharmacology*; D004558:Electric Stimulation / Q000379:methods; D009433:Neural Inhibition / Q000187:drug effects* / Q000502:physiology; D018034:Olfactory Receptor Neurons / Q000187:drug effects* / Q000502:physiology; D033521:Palinuridae / Q000187:drug effects* / Q000502:physiology; D018408:Patch-Clamp Techniques; D011392:Proline / Q000494:pharmacology*; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology; D013268:Stimulation, Chemical
D001120:Arginine; D011392:Proline; D003545:Cysteine