title: Pathophysiology and management of one-lung ventilation.
abstract: The ability to manage OLV effectively in patients with significant pulmonary disease is increasing. Knowledge of pulmonary ventilation and perfusion physiology, improvements in the ability to prevent and treat hypoxia, and a thorough grasp of traditional and novel ventilatory techniques may promote improved perioperative outcomes.
authors.affiliation: Department of Anesthesiology, Duke University Medical Center, Box 3094, Duke University Health Care Systems, Durham, NC 27710, USA. grich002@mc.duke.edu
authors.forename: Katherine P
authors.initials: KP
authors.lastname: Grichnik
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Clark
mesh_terms: D000768:Anesthesia, General / Q000009:adverse effects* / Q000379:methods*; D006801:Humans; D006935:Hypercapnia; D008171:Lung Diseases / Q000503:physiopathology*; D011187:Posture / Q000502:physiology; D011659:Pulmonary Gas Exchange / Q000502:physiology*; D012121:Respiration, Artificial / Q000009:adverse effects* / Q000379:methods*; D015656:Respiratory Mechanics; D019616:Thoracic Surgical Procedures; D014692:Ventilation-Perfusion Ratio / Q000502:physiology