NAC transcription factors: structurally distinct, functionally diverse.
NAC proteins constitute one of the largest families of plant-specific transcription factors, and the family is present in a wide range of land plants. Here, we summarize the biological and molecular functions of the NAC family, paying particular attention to the intricate regulation of NAC protein level and localization, and to the first indications of NAC participation in transcription factor networks. The recent determination of the DNA and protein binding NAC domain structure offers insight into the molecular functions of the protein family. Research into NAC transcription factors has demonstrated the importance of this protein family in the biology of plants and the need for further studies.
Olsen
Addie Nina
AN
Institute of Molecular Biology, University of Copenhagen, Øster Farimagsgade 2A, DK-1353 Copenhagen K, Denmark.
Ernst
Heidi A
HA
Leggio
Leila Lo
LL
Skriver
Karen
K
D000595:Amino Acid Sequence; D029681:Arabidopsis Proteins / Q000737:chemistry / Q000235:genetics; D016384:Consensus Sequence; D008958:Models, Molecular; D008969:Molecular Sequence Data; D010940:Plant Proteins / Q000378:metabolism*; D011487:Protein Conformation; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D015534:Trans-Activators / Q000378:metabolism*; D014157:Transcription Factors / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D014158:Transcription, Genetic
D029681:Arabidopsis Proteins; D010940:Plant Proteins; D015534:Trans-Activators; D014157:Transcription Factors; C493659:NAC019 protein, Arabidopsis