Outcome of radiation therapy for renal transplant rejection refractory to chemical immunosuppression.
Twenty consecutive patients with kidney graft rejection refractory to chemical immunosuppression were treated with local irradiation to the transplanted renal graft (3 x 1.5 Gy). Ten patients were complete responders (median follow-up: 47 months). Six patients were partial responders and failed after 1-4 months. Four patients did not respond.
Nuyttens
Joost J
JJ
Department of Radiation Oncology, Medical University of South Carolina, 169 Ashley Avenue, Charleston, SC 29425, USA.
Harper
Jennifer
J
Jenrette
Joseph M
JM
Turrisi
Andrew T
AT
D000293:Adolescent; D000328:Adult; D004351:Drug Resistance; D005260:Female; D006084:Graft Rejection / Q000532:radiotherapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007676:Kidney Failure, Chronic / Q000628:therapy; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
D007166:Immunosuppressive Agents