[Study on purification technology of patchouly oil with molecular distillation].
OBJECTIVE
To establish an advanced purification techniques of the essential oils obtained from Pogostemon cablin.


METHODS
Molecular distillation (MD) was applied.


RESULTS
Four distillates were obtained, chemical constituents of which were analyzed with GC-MS. Compared with those in original oils, the contents of active compounds (patchouli alcohol and pogostone) rose by 27%-47% in the distillates II and III.


CONCLUSIONS
Molecular distillation (MD) effectively raises the contents of patchouli alcohol and pogostone. The work is of great economic and scientific significance for the industrialization of P. cablin and the discovery of new drugs.
Hu
Hai-yan
HY
School of Pharmaceutical Sciences, Sun Yat-san University, Guangzhou 510275, China.
Peng
Jin-fu
JF
Huang
Shi-liang
SL
Wu
Li-hong
LH
Zhu
Bao-zhang
BZ
Xuan
Yao-ming
YM
Yang
De-po
DP
D008401:Gas Chromatography-Mass Spectrometry; D019686:Lamiaceae / Q000737:chemistry*; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry; D012717:Sesquiterpenes / Q000302:isolation & purification*; D013678:Technology, Pharmaceutical / Q000379:methods*
D009822:Oils, Volatile; C483658:Pogostone; D012717:Sesquiterpenes; C052983:patchouli alcohol