First fracture is associated with increased risk of new fractures during growth.
Prior fracture was associated with increased risk of new fracture in 601 members of a cohort studied between birth and l8 years. Hazard ratios for new fracture in data adjusted for age and sex were l.90 (95%CI l.51-2.39) after first fracture and 3.04 (95% CI 2.23-4.15) after second fracture.
Goulding
Ailsa
A
Department of Medical and Surgical Sciences, University of Otago, Dunedin, New Zealand. ailsa.goulding@stonebow.otago.ac.nz <ailsa.goulding@stonebow.otago.ac.nz>
Jones
Ianthe E
IE
Williams
Sheila M
SM
Grant
Andrea M
AM
Taylor
Rachael W
RW
Manning
Patrick J
PJ
Langley
John
J
D000293:Adolescent; D000367:Age Factors; D001842:Bone and Bones / Q000293:injuries*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D050723:Fractures, Bone / Q000150:complications*; D006801:Humans; D007223:Infant; D008297:Male; D012307:Risk Factors; D012737:Sex Factors; D013997:Time Factors