CrossChip: a system supporting comparative analysis of different generations of Affymetrix arrays.
CONCLUSIONS
To increase compatibility between different generations of Affymetrix GeneChip arrays, we propose a method of filtering probes based on their sequences. Our method is implemented as a web-based service for downloading necessary materials for converting the raw data files (*.CEL) for comparative analysis. The user can specify the appropriate level of filtering by setting the criteria for the minimum overlap length between probe sequences and the minimum number of usable probe pairs per probe set. Our website supports a within-species comparison for human and mouse GeneChip arrays.


BACKGROUND
http://www.crosschip.org
Kong
Sek Won
SW
Bauer Center for Genomics Research, Harvard University, Cambridge, MA, USA. skong@cgr.harvard.edu
Hwang
Kyu-Baek
KB
Kim
Richard D
RD
Zhang
Byoung-Tak
BT
Greenberg
Steven A
SA
Kohane
Isaac S
IS
Park
Peter J
PJ
D000465:Algorithms; D015342:DNA Probes / Q000235:genetics*; D020869:Gene Expression Profiling / Q000295:instrumentation / Q000379:methods*; D016247:Information Storage and Retrieval / Q000379:methods; D020411:Oligonucleotide Array Sequence Analysis / Q000295:instrumentation / Q000379:methods*; D016415:Sequence Alignment / Q000295:instrumentation / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000295:instrumentation / Q000379:methods*; D012984:Software
D015342:DNA Probes