Efficacy of ion-selective probes in early epicardial in vivo detection of myocardial ischemia.
Myocardial hypoxia is accompanied by increased epicardial potassium activity. In this experimental study in rabbits (n = 13), with ion-selective probes, we correlated our findings with an exact evaluation of myocardial oxygen tension, hemodynamic data and arterial and venous blood gas analysis. The epicardial potassium activity had good correlation with these parameters (pm = -0.95, pco = -0.93 and pa = -0.72, pv = -0.96, respectively). Therefore, the clinical use of these electrodes can be recommended for continuous monitoring in intensive care units.
Vogt
S
S
Cardiovascular Surgery, University Hospital of the Philipps-University Marburg, 35043 Marburg, Germany.
Troitzsch
D
D
Späth
S
S
Moosdorf
R
R
D000818:Animals; D002302:Cardiac Output; D019544:Equipment Failure Analysis; D017736:Ion-Selective Electrodes; D008297:Male; D017202:Myocardial Ischemia / Q000175:diagnosis* / Q000503:physiopathology*; D010100:Oxygen / Q000097:blood; D010496:Pericardium / Q000378:metabolism*; D011188:Potassium / Q000032:analysis* / Q000378:metabolism*; D011379:Prognosis; D011817:Rabbits; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013223:Statistics as Topic
D011188:Potassium; D010100:Oxygen