Cell culture models and animal models of viral hepatitis. Part II: hepatitis C.
The lack of a preventive vaccine, coupled with common unresponsiveness to treatment and coinfection with HIV, has made HCV a major threat to public health. The authors review in vitro and in vivo models that are being used to study HCV and to develop new treatments and preventive measures.
Guha
Chandan
C
Albert Einstein College of Medicine, 1300 Morris Park Ave., Bronx, NY 10461, USA.
Lee
Sung-W
SW
Chowdhury
Namita Roy
NR
Chowdhury
Jayanta Roy
JR
D000818:Animals; D018929:Cell Culture Techniques; D004195:Disease Models, Animal; D016174:Hepacivirus; D006526:Hepatitis C; D022781:Hepatocytes / Q000276:immunology / Q000821:virology; D051379:Mice; D008822:Mice, Transgenic / Q000821:virology*; D002679:Pan troglodytes / Q000821:virology*; D012452:Saguinus / Q000821:virology*; D014418:Tupaiidae / Q000821:virology*; D014779:Virus Replication