title: Peritoneal biphasic mesothelioma in a dog.
abstract: A 10-year-old German shepherd dog was presented with a severe abdominal distension. At necropsy, whitish and firm mass was observed in the mesentery with metastases in the pericardium and pleura. The intestinal serosa was thickened and stiff. Histologically, the tumours were composed of a biphasic population of cells, which reacted with cytokeratin, vimentin and Wilms' tumour 1 protein antibody. Ultrastructural examination revealed numerous microvilli, abundant rough endoplasmic reticulum, numerous desmosomes and bundles of microfilament. The tumour was classified as biphasic mesothelioma of peritoneal origin.
authors.affiliation: Laboratory of Veterinary Pathology, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-8510, Japan. t-sato@brs.nihon-u.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Sato
authors.forename: T
authors.initials: T
authors.lastname: Miyoshi
authors.forename: H
authors.initials: H
authors.lastname: Shibuya
authors.forename: J
authors.initials: J
authors.lastname: Fujikura
authors.forename: H
authors.initials: H
authors.lastname: Koie
authors.forename: Y
authors.initials: Y
authors.lastname: Miyazaki
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D017809:Fatal Outcome; D007150:Immunohistochemistry / Q000662:veterinary; D007633:Keratins / Q000032:analysis; D008297:Male; D008654:Mesothelioma / Q000473:pathology / Q000662:veterinary*; D009362:Neoplasm Metastasis; D010534:Peritoneal Neoplasms / Q000473:pathology / Q000662:veterinary*; D014746:Vimentin / Q000032:analysis
chemical_list: D014746:Vimentin; D007633:Keratins