title: [Synthesis of thieno[2,3-d]pyrimidines from 6-imino-6H-1,3-thiazine hydroperchlorates].
abstract: Mechanism of ring transformation reactions starting from substituted 6-imino-6H-1,3-thiazine hydroperchlorates is depending upon the substituent in position 5 of the thiazine nucleus. Starting from 4-methylthio-2-phenyl-6-imino-6H-1,3-thiazin-5-carbonitrile hydroperchlorat various 6-substituted 5-amino-4-methylthio-2-phenylthieno[2,3-d]pyrimidines can be obtained by reaction with acceptor substituted halogenmethanes under basic conditions in an one pot synthesis.
authors.affiliation: Institut for Pharmazie - Pharmazeutische Chemie, Fakultät für Biowissenschaften, Pharmazie und Psychologie, Universität Leipzig, Germany. briel@rz.uni-leipzig.de
authors.forename: D
authors.initials: D
authors.lastname: Briel
mesh_terms: D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010472:Perchlorates / Q000737:chemistry*; D011743:Pyrimidines / Q000737:chemistry*
chemical_list: D007202:Indicators and Reagents; D010472:Perchlorates; D011743:Pyrimidines