title: [Long-term follow-up observation of clinical therapy for laryngeal carcinoma recurrence and cervical metastasis].
abstract: OBJECTIVE
  To observe the long-term effects of clinical treatment for laryngeal carcinoma recurrence and cervical metastasis, and discuss the operative therapy method for laryngeal carcinoma recurrence and cervical metastasis.
  
  
  METHODS
  Retrospective analysis the 70 patients with laryngeal carcinoma recurrence and cervical metastasis who was cured in our hospital from 1990 to 1998, including 31 local recurrence, 15 stomal recurrence and 24 cervical lymph node metastasis.
  
  
  RESULTS
  Sixty-four cases were observed over 3 years and 41 cases were studied over 5 years. Twenty-eight patients who received the second-time operation survived over 5 years. In 31 patients with local recurrence, 19 patients received total laryngectomy and 15 patients of them are now living, but 12 patients who did not accept surgical therapy were died in 1-3 years separately; 9 patients with stomal recurrence received the second-time operation and 5 of them lived 5 years longer, however, the 6 patients with stomal recurrence who did not accept the second-time operation all died in 18 months; In 24 patients with cervical lymph node metastasis, 15 patients received the neck dissection and 8 of them are now alive, but the rest patients who did not accept the operation died in 2 years.
  
  
  CONCLUSIONS
  Regular re-examination and systemic clinical follow-up studying are very important for early detection and early treatment in laryngeal carcinoma recurrence and cervical metastasis; Second-time surgical operation is an effective therapeutic method for laryngeal carcinoma recurrence and cervical metastasis; Radiotherapy and chemotherapy play a limited role in clinical therapy for laryngeal carcinoma recurrence and cervical metastasis.
authors.affiliation: Department of Otolaryngology, Qilu Hospital of Shandong University, Jinan, 250012, China.
authors.forename: Weilun
authors.initials: W
authors.lastname: Chen
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Guo
authors.forename: Xinyong
authors.initials: X
authors.lastname: Luan
authors.forename: Chao
authors.initials: C
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009333:Neck; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D012189:Retrospective Studies