Adrenocortical carcinoma arising from a long-standing adrenal mass.
Adrenocortical carcinoma is a rare tumor with a dismal prognosis. In stark contrast, benign incidental adrenal lesions are detected commonly on routine abdominal imaging. We report a case of a 74-year-old man with a history of germ cell testicular carcinoma who presented with a 4.8-cm left adrenal lesion. The lesion remained stable for 8 years, at which time the patient became symptomatic from an excess of cortisol hormone. Biopsy findings confirmed adrenocortical carcinoma. We describe the presentation, clinical findings, diagnostic work-up, and follow-up of this patient and review the literature.
Cofield
Kattron R
KR
Department of General Surgery, Wake Forest University of Health Sciences, Winston-Salem, NC, USA.
Cantley
Larry K
LK
Geisinger
Kim R
KR
Zagoria
Ron J
RJ
Perrier
Nancy D
ND
D000306:Adrenal Cortex Neoplasms / Q000473:pathology*; D018268:Adrenocortical Carcinoma / Q000473:pathology*; D000368:Aged; D002471:Cell Transformation, Neoplastic; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D013997:Time Factors