Long-term benefits of monteplase before coronary angioplasty in acute myocardial infarction.
Patients with acute myocardial infarction were randomly assigned to receive direct percutaneous coronary intervention (PCI) or pretreatment with intravenous monteplase followed by PCI. Although the combination of monteplase and PCI did not alter mortality compared with direct PCI, there was a dramatic reduction in the cardiac event rate over a 2-year follow-up compared with direct PCI.
Inoue
Teruo
T
Department of Cardiovascular & Renal Medicine, Saga University Faculty of Medicine, Saga, Japan. inouete@med.saga-u.ac.jp
Nishiki
Ryoichi
R
Kageyama
Manabu
M
Chida
Ryuji
R
Hayashi
Terumi
T
Takayanagi
Kan
K
Hikichi
Yutaka
Y
Node
Koichi
K
D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D004638:Emergency Treatment; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000628:therapy*; D010960:Plasminogen Activators / Q000627:therapeutic use*; D011446:Prospective Studies; D055502:Secondary Prevention; D015912:Thrombolytic Therapy; D016896:Treatment Outcome
C468277:monteplase; D010960:Plasminogen Activators