title: Recent highlights in the pathophysiology of atopic eczema.
abstract: Atopic eczema (AE) belongs to the group of atopic diseases that have become increasingly prevalent over the last decades. The pathophysiology of AE has long remained enigmatic, but much scientific effort has been invested in elucidating the genetic background and the immunological mechanisms underlying AE, leading to a better understanding of this complex disease and to new therapeutic strategies. This review provides an update on the scientific progress that has been achieved in clarifying the pathophysiological mechanisms of AE.
authors.affiliation: Department of Dermatology, Friedrich Wilhelm University, Bonn, Germany.
authors.forename: J-P
authors.initials: JP
authors.lastname: Allam
authors.forename: T
authors.initials: T
authors.lastname: Bieber
authors.forename: N
authors.initials: N
authors.lastname: Novak
mesh_terms: D003876:Dermatitis, Atopic / Q000235:genetics / Q000276:immunology / Q000503:physiopathology*; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology
chemical_list: D007073:Immunoglobulin E