title: Magnetoencephalographic localization of the basal temporal language area.
abstract: Magnetoencephalography (MEG) recordings were made on 25 native English-speaking patients with localization-related epilepsy during a semantic language task (verb generation). Eighteen right-handed subjects with normal reading ability had MEG scans performed during the same language task. MEG data was analyzed by MR-FOCUSS, a current density imaging technique. Detectable MEG signals arising from activation in the left fusiform gyrus, also known as the basal temporal language area (BTLA), occurred at 167 +/- 18 ms (n = 43) in all subjects. The BTLA has been associated with a variety of language production and comprehension tasks involving processing of semantic, orthographic, and phonologic information. MEG may become an important tool in efforts to further define the linguistic operations of specific regions within this language area.
authors.affiliation: Department of Neurology, Henry Ford Health System, Detroit, MI 48202, USA. drsusan@umich.edu
authors.forename: Susan M
authors.initials: SM
authors.lastname: Bowyer
authors.forename: Toya
authors.initials: T
authors.lastname: Fleming
authors.forename: Margaret L
authors.initials: ML
authors.lastname: Greenwald
authors.forename: John E
authors.initials: JE
authors.lastname: Moran
authors.forename: Karen M
authors.initials: KM
authors.lastname: Mason
authors.forename: Barbara J
authors.initials: BJ
authors.lastname: Weiland
authors.forename: Brien J
authors.initials: BJ
authors.lastname: Smith
authors.forename: Gregory L
authors.initials: GL
authors.lastname: Barkley
authors.forename: Norman
authors.initials: N
authors.lastname: Tepley
mesh_terms: D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D002648:Child; D004827:Epilepsy / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007802:Language; D015225:Magnetoencephalography; D008297:Male; D008875:Middle Aged; D013702:Temporal Lobe / Q000502:physiology*