title: [Relationships between intravascular ultrasonographic findings and coronary risk factors in patients with normal coronary angiography].
abstract: OBJECTIVE
  Indicators of ischemic heart disease were studied for the practice of preventive medicine.
  
  
  METHODS
  Intravascular ultrasonography was performed in 97 patients with no abnormalities by left anterior descending artery angiography. Coronary risk factors were evaluated based on the relationship between plaque formation and lipoprotein levels.
  
  
  RESULTS
  Plaque was observed in 81% of patients. The relationship between mean plaque area(%) and the low-density lipoprotein/high-density lipoprotein(LDL/HDL)ratio was examined. Mean plaque area(%) was significantly higher at LDL/HDL < or = 2.5 than at LDL/HDL > 2.5. The border of significant change level of mean plaque area(%)was LDL/HDL = 2.5. There was a good correlation between mean plaque area (%) and LDL/HDL (r = 0.65, p < 0.01). Mean plaque area (%) at LDL/HDL 2.5 was calculated at 15%. Patients with coronary risk factors had LDL/HDL lower than 2.5 at mean plaque area of 15%.
  
  
  CONCLUSIONS
  Maintaining LDL/HDL at 2.5 is very important for preventive medicine. However, LDL/HDL should be managed at under 2.5 in patients with coronary risk factors.
authors.affiliation: Cardiovascular Center, Toho University School of Medicine, Sakura Hospital, Chiba. hfnoike@sakura.med.toho-u.ac.jp
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Noike
authors.forename: Takashi
authors.initials: T
authors.lastname: Hitsumoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Sakurai
authors.forename: Yuko
authors.initials: Y
authors.lastname: Sugiyama
authors.forename: Shin
authors.initials: S
authors.lastname: Sato
authors.forename: Takuo
authors.initials: T
authors.lastname: Iizuka
authors.forename: Mao
authors.initials: M
authors.lastname: Takahashi
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Shimizu
authors.forename: Keijiro
authors.initials: K
authors.lastname: Nakamura
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Ohsawa
mesh_terms: D000367:Age Factors; D000368:Aged; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D017023:Coronary Angiography; D003327:Coronary Disease / Q000517:prevention & control; D003331:Coronary Vessels / Q000473:pathology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000517:prevention & control*; D012307:Risk Factors; D018084:Ultrasonography, Interventional
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL