Single cell studies of the cell cycle and some models.
Analysis of growth and division often involves measurements made on cell populations, which tend to average data. The value of single cell analysis needs to be appreciated, and models based on findings from single cells should be taken into greater consideration in our understanding of the way in which cell size and division are co-ordinated. Examples are given of some single cell analyses in mammalian cells, yeast and other microorganisms. There is also a short discussion on how far the results are in accord with simple models.
Mitchison
J M
JM
Institute for Cell, Animal and Population Biology, University of Edinburgh, Edinburgh EH9 3JT, UK. j.m.mitchison@ed.ac.uk
D002453:Cell Cycle; D005057:Eukaryotic Cells / Q000166:cytology*; D015726:Giant Cells / Q000166:cytology; D008954:Models, Biological; D012441:Saccharomyces cerevisiae / Q000166:cytology