title: [Survey of the utilization and adverse effects of antibacterial drugs in patients admitted for respiratory diseases].
abstract: OBJECTIVE
  To evaluate the utilization of antibacterial drugs and their adverse effects in patients admitted for respiratory disease based on medical record review.
  
  
  METHODS
  The medical records of 141 inpatients admitted in 2002 for respiratory diseases were reviewed. The drug utilization index (DUI) and daily cost of antibacterial drugs were calculated, with also assessment of the adverse effects in relation to the drug use.
  
  
  RESULTS
  The DUI ranged from 0.9 to 1.1 in 66.7% of the patients, and the daily cost of the antibacterial drugs was 317.8+/-194.3 RMB, with a total of 14 cases with adverse drug effects recorded.
  
  
  CONCLUSIONS
  The utilization of antibacterial drugs was basically adequate in Nanfang Hospital though with occasional abuse of cefoperazone and sulbactam, inappropriate combination and high cost of the antibacterial drugs. More careful application of these drugs in old patients is stressed.
authors.affiliation: Department of Pharmacy, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhang
authors.forename: Jun
authors.initials: J
authors.lastname: Xu
authors.forename: Ping
authors.initials: P
authors.lastname: Zheng
authors.forename: Ying
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000191:economics / Q000627:therapeutic use*; D001991:Bronchitis / Q000188:drug therapy; D002438:Cefoperazone / Q000627:therapeutic use; D005260:Female; D006760:Hospitalization; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000188:drug therapy*; D013407:Sulbactam / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D002438:Cefoperazone; D013407:Sulbactam