title: The possible contribution of 129I in the drinking water and food supply to the nodular formation of thyroid tissue.
abstract: Nodular formation of the thyroid tissue can occur as a result of exposure to radiation. The nodular goiter is a common disease seen in the city of Elazig and its surroundings, in the eastern part of Turkey. A prospective study was conducted in an effort to identify the role of 129I in drinking water supply. Specimens obtained from nodular and normal thyroid tissue during surgery and also water specimens were counted by nuclear spectrometric system. 129I radioactivity in nodular tissue was noted to be higher compared to normal tissue and the difference was statistically significant (p <0.05). There was no statistically significant difference (p >0.05) between 129I radioactivity in the water supply and tissue obtained from the patients who have malignant or benign nodular lesions. These results support that the 129I radioactivity level in the water supply is one of the risk factors of the nodular formation of the thyroid tissue in the eastern part of Turkey.
authors.affiliation: Firat University, School of Medicine, Department of General Surgery, Elazig, 23200, Turkey.
authors.forename: Osman
authors.initials: O
authors.lastname: Dogru
authors.forename: Mahmut
authors.initials: M
authors.lastname: Dogru
authors.forename: Erhan
authors.initials: E
authors.lastname: Aygen
authors.forename: Cemalettin
authors.initials: C
authors.lastname: Camci
authors.forename: Cuneyt
authors.initials: C
authors.lastname: Kirkil
authors.forename: Cumhur
authors.initials: C
authors.lastname: Canbazoglu
authors.forename: Sultan
authors.initials: S
authors.lastname: Sahin
mesh_terms: D000328:Adult; D015984:Causality; D005260:Female; D005507:Food Contamination, Radioactive / Q000032:analysis* / Q000706:statistics & numerical data*; D005523:Food Supply / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D007457:Iodine Radioisotopes / Q000032:analysis*; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology*; D011829:Radiation Dosage; D011834:Radiation Monitoring / Q000379:methods; D011835:Radiation Protection / Q000379:methods; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D013223:Statistics as Topic; D016606:Thyroid Nodule / Q000453:epidemiology*; D014421:Turkey / Q000453:epidemiology; D014875:Water Pollutants, Radioactive / Q000032:analysis*; D014881:Water Supply / Q000032:analysis / Q000706:statistics & numerical data
chemical_list: D007457:Iodine Radioisotopes; D014875:Water Pollutants, Radioactive