title: National survey of patients with hemophilia and other congenital bleeding disorders in Thailand.
abstract: A national survey of patients with hemophilia and other congenital bleeding disorders in Thailand was conducted in the years 2000 to 2002. Questionnaires were sent to physicians working at hospitals throughout the country. Although the overall response rate to the questionnaires was 19%, the two highest rates of 80% and 73.7% were found at university and regional hospitals, respectively, where most of the patients received their diagnosis and treatment. A total of 1,450 patients comprised of hemophilia 1,325 cases, von Willebrand disease, 69 cases, congenital factor VII deficiency, 15 cases, hereditary platelet dysfunction, 22 cases, and undefined causes of congenital bleeding disorders, 19 cases. Most were pediatric patients <15 years of age. Treatment was mainly given on demand for a bleeding episode, while only 8.6% received additional home treatment for early bleeding episodes. Replacement therapy primarily relied on fresh frozen plasma, cryoprecipitate and cryo-removed plasma. Factor concentrate was seldom used because of the high price. As a result, hemophilia care services in Thailand should be strengthened by providing comprehensive education for medical personnel, making available simple laboratory kits to determine hemophilia A and B, ensuring an adequate supply of blood components and affordable factor concentrate, and establishing home care treatment.
authors.affiliation: Faculty of Medicine at Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. raajs@mahidol.ac.th
authors.forename: Ampaiwan
authors.initials: A
authors.lastname: Chuansumrit
authors.forename: Chularatana
authors.initials: C
authors.lastname: Mahasandana
authors.forename: Yingyong
authors.initials: Y
authors.lastname: Chinthammitr
authors.forename: Boonchu
authors.initials: B
authors.lastname: Pongtanakul
authors.forename: Vichai
authors.initials: V
authors.lastname: Laossombat
authors.forename: Weerasak
authors.initials: W
authors.lastname: Nawarawong
authors.forename: Yuchinda
authors.initials: Y
authors.lastname: Lektakul
authors.forename: Somporn
authors.initials: S
authors.lastname: Wangruangsatid
authors.forename: Ladda
authors.initials: L
authors.lastname: Sriboriboonsin
authors.forename: Ponlapat
authors.initials: P
authors.lastname: Rojnakarin
authors.forename: Pantep
authors.initials: P
authors.lastname: Angchaisuksiri
mesh_terms: D000293:Adolescent; D025861:Blood Coagulation Disorders, Inherited / Q000453:epidemiology* / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D019538:Health Care Surveys; D006295:Health Resources; D006306:Health Surveys; D006467:Hemophilia A / Q000453:epidemiology* / Q000628:therapy*; D006699:Home Care Services; D006767:Hospitals, District; D006785:Hospitals, University; D006801:Humans; D008297:Male; D017063:Outcome Assessment, Health Care; D015995:Prevalence; D011795:Surveys and Questionnaires; D013785:Thailand / Q000453:epidemiology