[The role of chromium in cell biology and medicine].
Chromium (Cr3+) is an essential trace element for animals and humans. Its deficiency in organisms causes e.g. disturbances of carbohydrate and lipid metabolism, hypoglycemia, impaired glucose tolerance, elevated cholesterol and triglycerides in blood, but a decrease in HDL-cholesterol. It plays an important role in insulin-receptor activation. In the literature, antioxidative and anti-diabetic effects of chromium were also described. An excess of trivalent chromium can act as a prooxidant.
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Instytut Ochrony Srodowiska, Wydział Matematyczno-Przyrodniczy KUL.
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D000975:Antioxidants / Q000378:metabolism / Q000494:pharmacology*; D008076:Cholesterol, HDL / Q000378:metabolism; D008078:Cholesterol, LDL / Q000378:metabolism; D002857:Chromium / Q000378:metabolism / Q000494:pharmacology*; D003920:Diabetes Mellitus / Q000378:metabolism; D004734:Energy Metabolism / Q000187:drug effects*; D006801:Humans; D050356:Lipid Metabolism; D010084:Oxidation-Reduction; D018384:Oxidative Stress / Q000187:drug effects*; D014131:Trace Elements / Q000494:pharmacology; D014280:Triglycerides / Q000378:metabolism
D000975:Antioxidants; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014131:Trace Elements; D014280:Triglycerides; D002857:Chromium