Naravelia zeylanica [corrected] occurrence of primary benzamides in flowering plants.
Extract of Naravelia zeylanica (Ranunculaceae) yielded three simple benzamides, 3,4-methylenedioxybenzamide, 4-methoxybenzamide and 4-hydroxy-3-methoxybenzamide. These simple C6C1 metabolites have been encountered as natural products for the first time. The compounds were identified by direct comparison of their spectral (1H- and 13C-NMR) and chromatographic (GCMS) data with those of authentic samples. Authentic 4-hydroxy-3-methoxybenzamide was synthesized in one step by treatment of 4-hydroxy-3-methoxybenzonitrile with sodium perborate. Authentic 3,4-methylenedioxybenzamide was synthesized from the corresponding acid.
Jaroszewski
Jerzy W
JW
Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, Universitetsparken 2, DK-2100 Copenhagen, Denmark. jj@dfuni.dk
Staerk
Dan
D
Holm-Móller
Sören Boe
SB
Jensen
Thomas Hógh
TH
Franzyk
Henrik
H
Somanadhan
Brinda
B
D001549:Benzamides / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification*; D035264:Flowers / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000032:analysis; D029626:Ranunculaceae / Q000737:chemistry*
D001549:Benzamides; D010936:Plant Extracts