title: Transferrin: structure, function and potential therapeutic actions.
abstract: There are many proteins that can multi-task. Transferrin, widely known as an iron-binding protein, is one such example of a multi-tasking protein. In this review, the multiple biological actions of transferrin, including its growth and cytoprotective activities, are discussed with the view of highlighting the potential therapeutic applications of this protein.
authors.affiliation: Research and Development, CSL Ltd., Bioplasma Division, 189-209 Camp Road, Broadmeadows, Victoria 3047, Australia. Peter.Gomme@csl.com.au
authors.forename: Peter T
authors.initials: PT
authors.lastname: Gomme
authors.forename: Karl B
authors.initials: KB
authors.lastname: McCann
authors.forename: Joseph
authors.initials: J
authors.lastname: Bertolini
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001692:Biological Transport; D016026:Bone Marrow Transplantation; D002318:Cardiovascular Diseases / Q000188:drug therapy; D006801:Humans; D007501:Iron / Q000378:metabolism; D009369:Neoplasms / Q000188:drug therapy; D011878:Radiotherapy; D011990:Receptors, Transferrin / Q000502:physiology; D014168:Transferrin / Q000737:chemistry* / Q000502:physiology* / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D011990:Receptors, Transferrin; D014168:Transferrin; D007501:Iron