title: [Anterior myocardial infarction in a chronic alcoholic man on disulfiram therapy: a case report].
abstract: Disulfiram is a drug used since 1940 in the treatment of alcohol dependence. However, it is not a completely safe drug; there are in the literature some case reports of more severe reaction than the usual "acetaldehyde syndrome" secondary to ingestion of disulfiram and alcohol. We describe a case of a 45-year-old, chronic alcoholic man in treatment with disulfiram, who suffered an acute anterior myocardial infarction, successfully treated with thrombolysis. The possible factors precipitating acute myocardial infarction in this patient are discussed.
authors.affiliation: U.O. di Cardiologia-ARC, Azienda Ospedaliera S. Maria degli Angeli, Pordenone. gnucifora@cardionet.it
authors.forename: Gaetano
authors.initials: G
authors.lastname: Nucifora
authors.forename: Matteo
authors.initials: M
authors.lastname: Cassin
authors.forename: Francesca
authors.initials: F
authors.lastname: Brun
authors.forename: Gian Luigi
authors.initials: GL
authors.lastname: Nicolosi
mesh_terms: D000427:Alcohol Deterrents / Q000009:adverse effects* / Q000627:therapeutic use; D000437:Alcoholism / Q000188:drug therapy*; D004221:Disulfiram / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000139:chemically induced*
chemical_list: D000427:Alcohol Deterrents; D004221:Disulfiram