[Structural changes of the myocardium and 24-hour blood pressure profile in subjects with hypertension studied during expedition work in the Far North].
Echocardiography and 24-hour BP monitoring were carried out in 177 men with stage 1 and 2 essential hypertension aged 25-59 years when they worked the Far North shift (group l) and in 75 patients with essential hypertension living in moderate climatic zone (group 2). Normal left ventricular geometry was found in 10 and 39% of subjects in groups l and 2, respectively. Left ventricular hypertrophy (LVH) was 2 times more frequent in group 1 where it was predominantly concentric. Contrary to group 2 significant correlations between parameters of 24-hour BP monitoring and echocardiography were found in group 1. All variants of left ventricular geometry in group 1 were characterized by lower systolic BP, high variability of systolic and diastolic BP, impaired 24-hour BP rhythm because of decreased night-day difference. Group 1 subjects with concentric left ventricular hypertrophy had significantly increased left ventricular mass index. Diastolic nocturnal hypertension was the factor most closely related to the structural state of the myocardium in group 1.
Gapon
L I
LI
Shurkevich
N P
NP
Vetoshkin
A S
AS
D000328:Adult; D001110:Arctic Regions; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory; D004452:Echocardiography; D005101:Expeditions; D006801:Humans; D006973:Hypertension / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology*; D017379:Hypertrophy, Left Ventricular / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*