Circulating soluble CD44 is higher among women than men and is not associated with cardiovascular risk factors or subclinical atherosclerosis.
In the present study, the associations between the plasma concentration of soluble CD44 (sCD44), sex, cardiovascular risk factors, and ultrasound-assessed measures of carotid atherosclerosis were examined in 2 groups of 61- and 64-year-old men and women from population-based samples. Women had higher levels of circulating sCD44 than men. There were no associations between sCD44 and cardiovascular risk factors or subclinical atherosclerosis.
Sjöberg
Sara
S
Wallenberg Laboratory for Cardiovascular Research, Sahlgrenska Academy at Göteborg University, 413 45 Göteborg, Sweden.
Fogelstrand
Linda
L
Hulthe
Johannes
J
Fagerberg
Björn
B
Krettek
Alexandra
A
D001161:Arteriosclerosis / Q000097:blood* / Q000453:epidemiology*; D002318:Cardiovascular Diseases / Q000097:blood* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D018960:Hyaluronan Receptors / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011153:Population; D012307:Risk Factors; D012727:Sex Characteristics
D018960:Hyaluronan Receptors