Cyclocarbopalladation: sequential cyclization and C-h activation/Stille cross-coupling in the Pd-5-exo-dig reaction.
A new cyclization and C-H activation/Stille cross-coupling reaction on a nonactivated aromatic has been discovered. The reaction is regioselective and controlled by the stannylated reagent. Labeling experiments have been performed that provide evidence for a complete transfer of the deuterium through the coordination sphere of palladium. [reaction: see text]
Bour
Christophe
C
Université Louis Pasteur de Strasbourg (UMR 7081 CNRS/ULP), Faculté Pharmacie, 74 route du Rhin, 67401 Illkirch-Cedex, France.
Suffert
Jean
J
D002384:Catalysis; D003500:Cyclization; D008958:Models, Molecular; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D011084:Polycyclic Aromatic Hydrocarbons / Q000138:chemical synthesis*
D011084:Polycyclic Aromatic Hydrocarbons; D010165:Palladium