title: [Effects of adipose tissue extract on rat skin regeneration in vitro].
abstract: OBJECTIVE
  To investigate the effects of adipose tissue extract on growth of rat skin in vitro.
  
  
  METHODS
  Neonatal rat skin (area of 2 mm x 2 mm) was cultured in Dulbecco's modified Eagle's medium (DMEM) containing 10% adipose tissue extract and 10% phosphate buffered solution (PBS). After being cultured for 6 days, the area of skin was measured.
  
  
  RESULTS
  Skin in both groups grew in area. With the addition of adipose tissue extract, the skin measured (8.43+/-1.40) mm2 in area after 6 days, and it was approximately 2 times of that of PBS group, in which the skin area was (4.18+/-1.11) mm2. The difference was statistically significant (P<0.05).
  
  
  CONCLUSIONS
  Adipose tissue extract promote skin growth, which may be attributed to the presence of some growth factors in the extract.
authors.affiliation: Key Research Laboratory of Wound Repair, Burns Institute, 304th Clinical Department of General Hospital of PLA, Beijing 100037, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Lu
authors.forename: Xiao-bing
authors.initials: XB
authors.lastname: Fu
authors.forename: Hai-hong
authors.initials: HH
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Chen
authors.forename: Xiu-ling
authors.initials: XL
authors.lastname: Ma
authors.forename: Tong-zhu
authors.initials: TZ
authors.lastname: Sun
mesh_terms: D000273:Adipose Tissue; D000818:Animals; D066298:In Vitro Techniques; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012038:Regeneration / Q000187:drug effects*; D012867:Skin / Q000187:drug effects*; D013552:Swine; D014020:Tissue Extracts / Q000494:pharmacology*
chemical_list: D014020:Tissue Extracts