title: Renal cell carcinoma in childhood.
abstract: The renal cell carcinoma (RCC) rarely occurs in childhood. We report here 3 cases of RCC in children. Two girls and 1 boy aged 14, 8 and 13 years old, respectively, presented with gross hematuria as their main complaint. They underwent ultrasonography and computerized tomography, which revealed unilateral renal tumor with lymph nodal involvement in all 3 cases. They were treated with radical nephrectomy associated with regional lymphadenectomy, with histopathology of RCC. Incomplete adjuvant radiotherapy was performed in 2 cases and no complementary treatment in the other one. All are disease-free in a period ranging from 9 to 77 months after diagnosis. Radical nephrectomy associated with regional lymphadenectomy is the best treatment for RCC in childhood. The disease appears to have a less aggressive behavior in children.
authors.affiliation: Section of Urology, Ipiranga Hospital, São Paulo, SP, Brazil. lucianobarros@terra.com.br
authors.forename: Luciano R
authors.initials: LR
authors.lastname: Barros
authors.forename: Sidney
authors.initials: S
authors.lastname: Glina
authors.forename: Luiz F
authors.initials: LF
authors.lastname: Melo
mesh_terms: D000293:Adolescent; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000601:surgery; D002648:Child; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000601:surgery; D008297:Male