[ASCUS of metaplastic type. Cyto-histopathological correlations].
We evaluated the cytopathological changes and the prognostic significance of atypical squamous metaplastic cells in cervical smears. 50 ASCUS cases were divided in two groups: 25 cases in different settings and 25 of metaplastic type. All cases were re-evaluated after 6 months and when necessary, verified by biopsy. The second cytological diagnosis was: group I--13 normal, 2 LSIL, 40 ASCUS; group II--6 normal, 2 LSIL, 2 HSIL and 15 ASCUS. The HPV was positive in 5 cases in group I and in 9 cases in group II. In ASCUS persistent cases the biopsy revealed: in group I--3 CIN 1 and 1 CIN 2 cases; in group II--1 CIN 1, 2 CIN II, 2 CIN III and one case of microinvasive carcinoma. In conclusion, atypical metaplastic cells are more frequently involved in serious cervical lesions.
Teleman
S
S
Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină, Disciplina de Morfopatologie.
Anton
Cristina
C
Socolov
Demetra
D
Ungureanu
Carmen
C
Danciu
M
M
Mihailovici
Maria Sultana
MS
D000328:Adult; D002278:Carcinoma in Situ / Q000473:pathology / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D002578:Uterine Cervical Dysplasia / Q000473:pathology* / Q000648:ultrastructure; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000648:ultrastructure; D014626:Vaginal Smears