Double dissociation of V1 and V5/MT activity in visual awareness.
The critical time windows of the contribution of V1 and V5/MT to visual awareness of moving visual stimuli were compared by administering transcranial magnetic stimulation (TMS) to V1 or V5/MT in various time intervals from stimulus offset during performance of a simple motion detection task. Our results show a double dissociation in which the critical period of V1 both predates and postdates that of V5/MT, and where stimulation of either V1 at V5/MT's critical period or V5/MT at V1's critical period does not impair performance. These findings demonstrate the importance of back-projections from V5/MT to V1 in awareness of real motion stimuli.
Silvanto
Juha
J
Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK. juha.silvanto@ucl.ac.uk
Lavie
Nilli
N
Walsh
Vincent
V
D001364:Awareness / Q000502:physiology*; D046690:Deep Brain Stimulation / Q000379:methods*; D005074:Evoked Potentials, Visual / Q000502:physiology*; D006801:Humans; D009039:Motion Perception / Q000502:physiology*; D010775:Photic Stimulation / Q000379:methods*; D014793:Visual Cortex / Q000502:physiology*