Selective polymorph transformation via solvent-drop grinding.
A method of inducing specific polymorph transformations is exemplified with two single-component systems, whereby a given crystal form undergoes conversion when subjected to solid state grinding in the presence of a minor quantity of a certain solvent.
Trask
Andrew V
AV
Pfizer Institute for Pharmaceutical Materials Science, Department of Chemistry, University of Cambridge, UK.
Shan
Ning
N
Motherwell
W D Samuel
WD
Jones
William
W
Feng
Shaohua
S
Tan
Reginald B H
RB
Carpenter
Keith J
KJ
D020650:Combinatorial Chemistry Techniques / Q000379:methods; D003460:Crystallization; D015394:Molecular Structure; D033362:Powder Diffraction; D012997:Solvents / Q000737:chemistry; D062367:ortho-Aminobenzoates / Q000737:chemistry*
D012997:Solvents; D062367:ortho-Aminobenzoates; C031385:anthranilic acid