Dynein cargo gets its groove back.
Recent work from the King lab (Wu et al., 2005) on the structure of the Tctex1 dynein light chain provides new insights into the mechanism of cytoplasmic dynein cargo binding and the functional significance of light chain isoform diversity.
Pfister
K Kevin
KK
D000818:Animals; D004398:Dyneins / Q000378:metabolism*; D008869:Microtubule-Associated Proteins / Q000737:chemistry*; D009687:Nuclear Proteins / Q000737:chemistry*; D011487:Protein Conformation; D020033:Protein Isoforms / Q000737:chemistry; D056427:t-Complex Genome Region
D008869:Microtubule-Associated Proteins; D009687:Nuclear Proteins; D020033:Protein Isoforms; D004398:Dyneins