Ewing sarcoma as a second malignant neoplasm after acute lymphoblastic leukemia.
Second malignant neoplasms (SMNs) are being increasingly recognized. This report describes a case of a 7-year-old girl with a history of acute lymphoblastic leukemia (ALL) who presented with a mass in her humerus that was diagnosed as Ewing sarcoma. Second malignant neoplasms are relatively rare in survivors of ALL treated without radiation. Even more unusual is the development of Ewing sarcoma as the SMN.
Kim
Grace E
GE
UCSF Children's Hospital, San Francisco, California 94143-0106, USA.
Beach
Barbara
B
Gastier-Foster
Julie M
JM
Murata-Collins
Joyce L
JL
Rowland
Jon M
JM
O'Donnell
Richard J
RJ
Goldsby
Robert E
RE
D001859:Bone Neoplasms / Q000235:genetics / Q000473:pathology; D002648:Child; D005260:Female; D006801:Humans; D006811:Humerus; D016609:Neoplasms, Second Primary / Q000235:genetics / Q000473:pathology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma; D012512:Sarcoma, Ewing / Q000235:genetics / Q000473:pathology