title: Novel jadomycins: incorporation of non-natural and natural amino acids.
abstract: Electrospray ionization mass spectrometry of extracts from Streptomyces venezuelae ISP5230 cultures grown on chemically synthesized non-natural L-amino acids, D-amino acids or any of the 20 natural amino acids demonstrated incorporation of the amino acid into a jadomycin B analogue.
authors.affiliation: College of Pharmacy, Dalhousie University, 5968 College street, Halifax, Nova Scotia, B3H 3J5, Canada. david.jakeman@dal.ca
authors.forename: David L
authors.initials: DL
authors.lastname: Jakeman
authors.forename: Spring
authors.initials: S
authors.lastname: Farrell
authors.forename: Wendy
authors.initials: W
authors.lastname: Young
authors.forename: René J
authors.initials: RJ
authors.lastname: Doucet
authors.forename: Shannon C
authors.initials: SC
authors.lastname: Timmons
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D008968:Molecular Conformation; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods; D013302:Streptomyces / Q000737:chemistry*
chemical_list: D000596:Amino Acids; D007546:Isoquinolines; C081750:jadomycin B