[Endocrine obesity: bioelectric profiles (biotypes) detected in the body composition].
136 patients were selected (16 men and 120 women with non-specific menstrual disturbances) with a BMI (Body Mass Index) between 25 and 45 kg/m2, which were diagnosed with "disendocrinia" (GH deficit, hyperadrenocorticism, hypothyroidsm, hyperandrogenism, menstrual cycle disorders). The proposed approach, based on the visualization of the value distribution of the electric measures in different graphics, is able to immediately explain the bioelectric state of the individual's lean-mass. Subjects with hypothyroidism present, along with their overweight, less bio-conducting mass, with an altered fluid intra/extra-cellular distribution. Patients with hyperadrenocorticism show instead an hyperhydratation of the body mass, especially in the extracellular level. Patients with menstrual disorders (amenorrea, polycystic ovary syndrome, anovulatory cycle etc...) present a lean mass reduction (elevated Rs) and an increase of the intra-cellular compartment (elevated-Xc). Patients with hyper-androgenism (and hirsutism) show a characteristic bioelectric "pattern", with low Rs levels and high Xc levels. Subjects with GH deficit (men and women), has a trend of documenting bioelectric measures with lower lean mass and higher fat-mass. Different electric biotypes seem to characterize the body composition in the several endocrine disorders.
Miggiano
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GA
Servizio di Dietetica, Istituto di Biochimica e Biochimica Clinica, Facoltà di Medicina e Chirurgia, Università Cattolica S. Cuore, Roma, Italia.
Petitti
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D000273:Adipose Tissue / Q000473:pathology; D000308:Adrenocortical Hyperfunction / Q000150:complications; D001823:Body Composition; D015992:Body Mass Index; D001834:Body Water; D017097:Electric Impedance; D004700:Endocrine System Diseases / Q000150:complications* / Q000473:pathology; D045604:Extracellular Fluid / Q000737:chemistry; D005260:Female; D019382:Human Growth Hormone / Q000172:deficiency; D006801:Humans; D017588:Hyperandrogenism / Q000150:complications; D007037:Hypothyroidism / Q000150:complications; D007424:Intracellular Fluid / Q000737:chemistry; D008297:Male; D008599:Menstruation Disturbances / Q000150:complications; D009765:Obesity / Q000145:classification / Q000209:etiology* / Q000473:pathology
D019382:Human Growth Hormone