title: Enhanced expression of protein phosphatase 2A associated with hyper-phosphorylation of histone H1 in Alzheimer's disease brain.
abstract: In this study, we analyzed high expression of protein phosphatase (PP) 2A in Alzheimer's disease brain compared to that of the control brain, which result from hyperphosphorylation of histone H1. PP1alpha and PP1gamma1 were slightly expressed in all cases, but there was no relation to the levels of the phosphate in histone H1.
authors.affiliation: Department of Orthopaedic Surgery, Kagawa Medical College, Mikicho 1750-1, Kagawa 761-0701, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Mori
authors.forename: Yongping
authors.initials: Y
authors.lastname: Cao
authors.forename: Kenichi
authors.initials: K
authors.lastname: Sogawa
authors.forename: Kazuya
authors.initials: K
authors.lastname: Kondo
authors.forename: Tohru
authors.initials: T
authors.lastname: Sakai
authors.forename: Norifumi
authors.initials: N
authors.lastname: Hino
authors.forename: Hisakazu
authors.initials: H
authors.lastname: Yamashiro
authors.forename: Masanao
authors.initials: M
authors.lastname: Okada
authors.forename: Kazuo
authors.initials: K
authors.lastname: Miyamoto
authors.forename: Yoji
authors.initials: Y
authors.lastname: Kawaguchi
authors.forename: Tasuku
authors.initials: T
authors.lastname: Mashiba
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Norimatsu
mesh_terms: D000544:Alzheimer Disease / Q000201:enzymology / Q000378:metabolism*; D016022:Case-Control Studies; D006657:Histones / Q000378:metabolism*; D006801:Humans; D010749:Phosphoprotein Phosphatases / Q000378:metabolism*; D010766:Phosphorylation; D010770:Phosphotransferases / Q000378:metabolism*; D054648:Protein Phosphatase 2
chemical_list: D006657:Histones; D010770:Phosphotransferases; D010749:Phosphoprotein Phosphatases; D054648:Protein Phosphatase 2