Severe febrile systemic reaction to pneumococcal vaccine.
Polyvalent pneumococcal polysaccharide vaccine (Pneumovax, PPV) has been shown to substantially reduce the risk of Streptococcus pneumoniae infections in susceptible individuals. Side effects, such as mild local erythema, induration, pain and fever, have been reported with various frequencies. Rarely, systemic symptoms, including high fever, headache, nausea and photophobia, have been reported in the literature. This case report describes a 38-year-old male who developed severe and prolonged local and systemic symptoms necessitating hospitalization following a dose of pneumovax.
Hasan
Syed
S
Department of Medicine, Western Missouri Medical Center, Warrensburg, MO 64093, USA. syedphasan@hotmail.com
Yousef
Mahmoud
M
Shridharani
Sachin
S
D000208:Acute Disease; D000328:Adult; D005334:Fever / Q000139:chemically induced*; D006801:Humans; D007273:Injections, Intramuscular / Q000009:adverse effects; D008297:Male; D022242:Pneumococcal Vaccines / Q000008:administration & dosage / Q000009:adverse effects*; D011018:Pneumonia, Pneumococcal / Q000517:prevention & control*; D013296:Streptococcus pneumoniae / Q000276:immunology*
D022242:Pneumococcal Vaccines