[Pre- and post-prostatectomy variation and supplement of sexual hormones in patients with benign prostatic hyperplasia].
OBJECTIVE
To explore the variation of sexual hormones (T and fT) before and after prostatectomy and their post-operative supplement in patients with benign prostatic hyperplasia (BPH).


METHODS
Sixty-four cases of BPH were randomly divided into a treatment group (Group I, n = 25) and a control group (Group II, n = 39). Plasma LH, FSH, T and fT were measured by radioimmunoassay a week before and two weeks after prostatectomy. After operation, Group I received supplement of testosterone undecanoate, while Group II received none.


RESULTS
The variations of plasma LH, FSH, T and fT were not statistically significant in the two groups before prostatectomy (P > 0.05), but obviously less in Group I than in Group II after operation (P < 0.01).


CONCLUSIONS
Testosterone supplement is a useful therapy for post-prostatectomy patients with androgen deficiency.
Ren
Xiao-min
XM
Department of Urology, Shanghai Ninth Peoples Hospital Affiliated to Shanghai Second Medical University, Shanghai 200011, China. renxmb@online.sh.cn
Ying
Jun
J
Yao
De-hong
DH
Jiang
Yue-qing
YQ
Xu
Ming-xi
MX
D000368:Aged; D000369:Aged, 80 and over; D005640:Follicle Stimulating Hormone / Q000097:blood; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood; D011468:Prostatectomy; D011470:Prostatic Hyperplasia / Q000097:blood / Q000188:drug therapy* / Q000601:surgery; D013739:Testosterone / Q000031:analogs & derivatives* / Q000097:blood / Q000627:therapeutic use
D012739:Gonadal Steroid Hormones; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D017430:Prostate-Specific Antigen; C010792:testosterone undecanoate