A sensitive biosensor for lactate based on layer-by-layer assembling MnO2 nanoparticles and lactate oxidase on ion-sensitive field-effect transistors.
A sensitive enzyme-based FET biosensor for lactate has been obtained by introducing MnO2 nanoparticles at the gate surface via a layer-by-layer assembling method.
Xu
Jing-Juan
JJ
Key Lab of Analytical Chemistry for Life Science, Department of Chemistry, Nanjing University, Nanjing 210093, China. xujj@nju.edu.cn
Zhao
Wei
W
Luo
Xi-Liang
XL
Chen
Hong-Yuan
HY
D018441:Biofilms; D015374:Biosensing Techniques; D004800:Enzymes, Immobilized; D019344:Lactic Acid / Q000737:chemistry*; D017895:Manganese Compounds / Q000737:chemistry*; D006899:Mixed Function Oxygenases / Q000737:chemistry* / Q000378:metabolism; D049329:Nanostructures; D036103:Nanotechnology / Q000295:instrumentation* / Q000379:methods; D010087:Oxides / Q000737:chemistry*; D012815:Signal Processing, Computer-Assisted; D014173:Transistors, Electronic
D004800:Enzymes, Immobilized; D017895:Manganese Compounds; D010087:Oxides; D019344:Lactic Acid; D006899:Mixed Function Oxygenases; C021497:lactate 2-monooxygenase; C016552:manganese dioxide