A rare complication of secondary hyperparathyroidism. Brown tumor of the maxilla and mandible.
Brown tumors are focal bone lesions caused by increased osteoclastic activity and fibroblastic proliferation encountered in primary or more rarely secondary hyperparathyroidism. Ninety-two percent of the patients undergoing dialysis develop secondary hyperparathyroidism. Of these, approximately 1.5% develops brown tumors. Brown tumors of hyperparathyroidism may appear in any bone but are frequently found in the facial bones and jaws, particularly in long-standing cases of the disease. As it becomes common for hyperparathyroidism to be detected earlier during the disease, the bony manifestations of the disease are rarely seen. The following report describes a case of brown tumor of the maxilla and mandible in a patient with renal insufficiency. This patient presented multiple skeletal lesions, which are uncommonly seen nowadays.
Pinar Sumer
A
A
Department of Oral Diagnosis and Radiology, Faculty of Dentistry, University of Ondokuz Mayis, Samsun, Turkey. psumer1970@yahoo.com
Arik
Nurol
N
Sumer
Mahmut
M
Karagoz
Filiz
F
D000328:Adult; D001706:Biopsy; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D007676:Kidney Failure, Chronic / Q000150:complications; D008067:Lipoma / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D008334:Mandible / Q000473:pathology; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D008437:Maxilla / Q000473:pathology; D008441:Maxillary Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D016105:Parathyroidectomy; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology; D012008:Recurrence; D006435:Renal Dialysis; D014057:Tomography, X-Ray Computed