Diffuse choroidal haemangioma in Sturge-Weber syndrome treated with photodynamic therapy under general anaesthesia.
OBJECTIVE
To report the treatment outcome of photodynamic therapy with verteporfin (PDT) for exudative retinal detachment associated with diffuse choroidal haemangioma in Sturge-Weber syndrome.


METHODS
An interventional case report of a 12-year-old girl with Sturge-Weber syndrome who developed an exudative retinal detachment (visual acuity 20/400) that was treated with PDT under general anaesthesia. PDT was performed according to the standard (macular degeneration) protocol, using three nonoverlapping spots of 4,000 microm.


RESULTS
Subretinal fluid resolved completely over a period of 5 months and visual acuity increased to 20/50. No side effects of the PDT treatment were encountered during 9 months' follow-up.


CONCLUSIONS
In our patient PDT with verteporfin effectively resolved the exudative retinal detachment associated with a diffuse choroidal haemangioma. Resolution of subretinal fluid occurred over several months without retreatment. We noted no side effects of the combination PDT and general anaesthesia, nor did we encounter ocular side effects of the treatment.
Huiskamp
E A
EA
Department of Ophthalmology, University Hospital Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands. r.p.h.m.muskens@ohk.umcg.nl
Müskens
R P H M
RP
Ballast
A
A
Hooymans
J M M
JM
D000768:Anesthesia, General / Q000379:methods*; D002648:Child; D002830:Choroid Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005122:Exudates and Transudates; D005260:Female; D006391:Hemangioma / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use; D011166:Porphyrins / Q000627:therapeutic use; D012163:Retinal Detachment / Q000188:drug therapy*; D013341:Sturge-Weber Syndrome / Q000150:complications / Q000188:drug therapy*; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014463:Ultrasonography; D000077362:Verteporfin
D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin