Penicillium sclerotiorum catalyzes the conversion of herbertenediol into its dimers: mastigophorenes A and B.
Herbertenediol was subjected to biotransformation by Penicillium sclerotiorum. Spectral data analysis of the converted metabolites revealed that the neurotrophic active compounds, mastigophorenes A and B, dimeric to the substrate were formed.
Harinantenaina
Liva
L
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Japan.
Noma
Yoshiaki
Y
Asakawa
Yoshinori
Y
D001711:Biotransformation; D002240:Carbohydrate Sequence; D002384:Catalysis; D003517:Cyclopentanes / Q000737:chemistry* / Q000378:metabolism; D035926:Hepatophyta / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D010407:Penicillium / Q000737:chemistry* / Q000378:metabolism; D010636:Phenols / Q000737:chemistry* / Q000378:metabolism; D012717:Sesquiterpenes / Q000737:chemistry* / Q000378:metabolism; D021241:Spectrometry, Mass, Electrospray Ionization
D003517:Cyclopentanes; D010636:Phenols; D012717:Sesquiterpenes; C482283:herbertenediol; C500870:mastigophorene A; C500871:mastigophorene B