title: Diet and Japanese herbal medicine for recalcitrant atopic dermatitis: efficacy and safety.
abstract: We have been utilizing Kampo, a Japanese herbal medicine, together with lifestyle advice, for recalcitrant atopic dermatitis. To estimate the safety and efficacy of the treatment, we administered Kampo formulas to patients in whom conventional treatment failed to improve symptoms, along with dietary advice recommending traditional Japanese food. The therapeutic effects of Kampo formulas were assessed in 95 patients with recalcitrant atopic dermatitis who consulted our clinic from January to June, 2000. The overall result was 'markedly effective" in 19 patients (20%), "moderately effective" in 33 (35%), "slightly effective" in 36 (38%) and "ineffective" in four (4%). Three patients dropped out of the study. No adverse reactions in laboratory data were noted in examined patients. The most commonly used formula was Hochu-ekki-to containing Astragalus root, liquorice, jujube, ginseng, white Atractylodes rhizome, fresh ginger and Chinese Angelica root. Diet and Japanese herbal medicine are thought to be useful as an alternative therapy of intractable atopic dermatitis.
authors.affiliation: Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan. hiromik@med.osaka-cu.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Kobayashi
authors.forename: N
authors.initials: N
authors.lastname: Mizuno
authors.forename: H
authors.initials: H
authors.lastname: Teramae
authors.forename: H
authors.initials: H
authors.lastname: Kutsuna
authors.forename: S
authors.initials: S
authors.lastname: Ueoku
authors.forename: J
authors.initials: J
authors.lastname: Onoyama
authors.forename: K
authors.initials: K
authors.lastname: Yamanaka
authors.forename: N
authors.initials: N
authors.lastname: Fujita
authors.forename: M
authors.initials: M
authors.lastname: Ishii
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000178:diet therapy* / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D029001:Herbal Medicine / Q000379:methods*; D006801:Humans; D007223:Infant; D008297:Male; D020835:Medicine, Kampo; D008875:Middle Aged; D008517:Phytotherapy / Q000009:adverse effects / Q000379:methods
chemical_list: D004365:Drugs, Chinese Herbal