[Studies on chemical constituents from leaves of Securinega suffruticosa].
OBJECTIVE
To investigate the chemical constituents of Securinega suffruticosa.


METHODS
It was isolated and purified by silica gel chromatography. Their structures were elucidated by means of spectral analysis.


RESULTS
Four compounds were isolated and identified as ent-phyllanthidine (1), virosecurinine (2), 14,15-dihydrovirosecurinine (3) and viroallosecurinine (4).


CONCLUSIONS
All of four compounds were isolated from S. suffruticosa for the first time and were the enantiomers isolated from this plant before.
Wu
Hai-yan
HY
Institute of Material Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Zhou
Jin-yun
JY
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D001381:Azepines / Q000737:chemistry / Q000302:isolation & purification*; D019665:Euphorbiaceae / Q000737:chemistry*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry / Q000302:isolation & purification*; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010880:Piperidines / Q000737:chemistry / Q000302:isolation & purification*; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
D000470:Alkaloids; D001381:Azepines; D006576:Heterocyclic Compounds, 4 or More Rings; D007783:Lactones; D010880:Piperidines; C503182:ent-phyllanthidine; C012607:virosecurinine