title: Sodium transport in airway epithelium correlates with lung compliance in healthy newborn infants.
abstract: To study the relation between sodium transport in airway epithelium and postnatal pulmonary adaptation, we measured nasal potential difference at 1 to 4 hours and lung compliance at 21 to 48 hours after birth in 20 healthy infants. Sodium transport correlated with lung compliance ( r 2 = 0.40, P < .003). Airway sodium transport plays a role in postnatal pulmonary adaptation.
authors.affiliation: Department of Neonatology, Hospital for Children and Adolescents, Helsinki University Central Hospital, 00029-HUS, Helsinki, Finland.
authors.forename: Otto
authors.initials: O
authors.lastname: Helve
authors.forename: Olli
authors.initials: O
authors.lastname: Pitkänen
authors.forename: Turkka
authors.initials: T
authors.lastname: Kirjavainen
authors.forename: Sture
authors.initials: S
authors.lastname: Andersson
mesh_terms: D004847:Epithelial Cells / Q000378:metabolism; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D017136:Ion Transport; D008170:Lung Compliance / Q000502:physiology*; D008297:Male; D020545:Respiratory Mucosa / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism* / Q000493:pharmacokinetics
chemical_list: D012964:Sodium