title: Severe acute respiratory syndrome coronavirus 3a protein is a viral structural protein.
abstract: The present study showed the association of a severe acute respiratory syndrome coronavirus (SCoV) accessory protein, 3a, with plasma membrane and intracellular SCoV particles in infected cells. 3a protein appeared to undergo posttranslational modifications in infected cells and was incorporated into SCoV particles, establishing that 3a protein was a SCoV structural protein.
authors.affiliation: Department of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555-1019, USA.
authors.forename: Naoto
authors.initials: N
authors.lastname: Ito
authors.forename: Eric C
authors.initials: EC
authors.lastname: Mossel
authors.forename: Krishna
authors.initials: K
authors.lastname: Narayanan
authors.forename: Vsevolod L
authors.initials: VL
authors.lastname: Popov
authors.forename: Cheng
authors.initials: C
authors.lastname: Huang
authors.forename: Taisuke
authors.initials: T
authors.lastname: Inoue
authors.forename: Clarence J
authors.initials: CJ
authors.lastname: Peters
authors.forename: Shinji
authors.initials: S
authors.lastname: Makino
mesh_terms: D000818:Animals; D018938:Caco-2 Cells; D002522:Chlorocebus aethiops; D006801:Humans; D016253:Microscopy, Immunoelectron; D011499:Protein Processing, Post-Translational; D045473:Severe acute respiratory syndrome-related coronavirus / Q000235:genetics / Q000502:physiology* / Q000648:ultrastructure; D014709:Vero Cells; D014759:Viral Envelope Proteins; D014764:Viral Proteins / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D015678:Viral Structural Proteins / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D000086082:Viroporin Proteins
chemical_list: C487105:3a protein, SARS-CoV; D014759:Viral Envelope Proteins; D014764:Viral Proteins; D015678:Viral Structural Proteins; D000086082:Viroporin Proteins