title: [Pulmonary eosinophilic granuloma presenting as a solitary pulmonary nodule].
abstract: A symptomless 60 year old man with a heavy smoking history presented with a nodule in the right lung, which was found by an annual chest X-ray. Chest CT showed a 1 cm speculated nodule in the right S8. Bronchoscopic transbronchial biopsy to the nodule yielded no definite diagnosis. Since the nodule was highly suggestive of lung cancer, wedge resection was performed by video-assisted thoracoscopic surgery. Pathological findings of the specimen showed that the nodule consisted of a mixed population of histiocytoid cells with eosinophils. The nuclei and cytoplasms of the histiocytoid cells were stained positively for S-100 protein. Pulmonary eosinophilic granuloma (PEG) was diagnosed. Common radiographic findings of PEG should present with a mixture of multiple nodular shadows and cystic lesions. PEG presenting as a solitary nodule is rare.
authors.affiliation: Department of Respiratory and Cardiovascular Medicine, Shiga University of Medical Science.
authors.forename: Takashi
authors.initials: T
authors.lastname: Hajiro
authors.forename: Kyosuke
authors.initials: K
authors.lastname: Ishihara
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Fujii
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kaneko
authors.forename: Katsuyama
authors.initials: K
authors.lastname: Eiji
mesh_terms: D003937:Diagnosis, Differential; D004803:Eosinophilic Granuloma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging*