title: Detecting glioma invasion of the corpus callosum using diffusion tensor imaging.
abstract: We present a patient with a recurrent glioblastoma and abnormalities of the corpus callosum seen on diffusion tensor MRI that were not seen on conventional imaging. These abnormalities preceded the development of the tumour. We describe the technique of diffusion tissue signatures to assess tissue infiltration by tumours compared with values from normal volunteers.
authors.affiliation: Academic Neurosurgical Unit, Addenbrooke's Hospital, Cambridge, UK. sip58@cam.ac.uk
authors.forename: S J
authors.initials: SJ
authors.lastname: Price
authors.forename: A
authors.initials: A
authors.lastname: Peña
authors.forename: N G
authors.initials: NG
authors.lastname: Burnet
authors.forename: J D
authors.initials: JD
authors.lastname: Pickard
authors.forename: J H
authors.initials: JH
authors.lastname: Gillard
mesh_terms: D001037:Aphasia / Q000209:etiology; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000601:surgery; D003337:Corpus Callosum / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D005260:Female; D005910:Glioma / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000601:surgery