[Peculiarities of human lung prenatal morphogenesis at the first trimester of pregnancy in different periods after Chernobyl accident].
The comparative histological and morphometric analysis of the bronchial structures of human fetal lungs was performed. Fetal lungs were taken from pregnant women living in radionuclide polluted zones (Novozibcov, Bryansk region) or in control regions (Moscow) in different periods after Chernobyl accident. Relative areas of the bronchial epithelial tubes and mesenchyme, quantity of bronchial branches and buds (end sections) of epithelial tubes on cut area unit were determined. The dates received in 1992-1993 showed the delay of fetal bronchial growth and branching in comparison with control. It can be estimated as tissue dysplasia of lungs from fetuses of mothers living in Novozibcov. The material received in 1995 showed the more intensive growth of bronchial branches in human fetal lungs than the material from Novozibcov and of the Moscow control, taken in 1992-1993. These date suggest the heterogenous character of lung prenatal morphogenesis reactions of offspring from pregnant women lived in different periods on controllable territories of Bryansk region.
Romanova
L K
LK
Riabchikov
O P
OP
Zhorova
E S
ES
Bugrilova
R S
RS
Makarova
L F
LF
D001980:Bronchi / Q000033:anatomy & histology / Q000196:embryology* / Q000528:radiation effects*; D016022:Case-Control Studies; D047852:Chernobyl Nuclear Accident; D005260:Female; D047109:Fetal Development / Q000528:radiation effects; D005333:Fetus / Q000033:anatomy & histology / Q000528:radiation effects*; D006801:Humans; D009024:Morphogenesis; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D018788:Radioactive Hazard Release; D014586:USSR