[Isolation and identification of a new cucurbitacin from Picria fel-terrae].
OBJECTIVE
To study compounds isolated from Picria fel-terrae.


METHODS
The chemical constituents were separated and purified by column chromatography on silica gel and MCI. Their structures were identified on the basis of spectral data (IR, UV, MS, ID NMR and 2D NMR).


RESULTS
A new cucurbitacin, along with a known one, were obtained from the 60% EtOH extract of the whole plant.


CONCLUSIONS
The new compound was identified as 11, 24-dioxo-5, 21-diene-cucurbit-3alpha-O-beta-D-xylopyranosyl-16alpha-O-alpha-L-rhamnopyranoside (dehydrobryogenin glycoside). The known one, hexanorcucurbitacin F, was obtained for the first time from Picria fel-terrae.
Zou
Jie-Ming
JM
Guilin Sanjin Pharmaceutical Co. Ltd., Guilin 541004, China. Sanjin@gl.gx.cninfo.net
Wang
Li-Sheng
LS
Ma
Xue-Min
XM
Shi
Ren-Bing
RB
Guo
Ya-Jian
YJ
D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D028083:Scrophulariaceae / Q000737:chemistry*; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification
C502281:11,24-dioxo-5,21-dienecucurbit-3-O-xylopyranosyl-16-O-rhamnopyranoside; D012503:Saponins; D013256:Steroids; C502282:hexanorcucurbitacin F