Tenosynovitis of the wrist due to resistant Mycobacterium tuberculosis in a heart transplant patient.
Tubercular tenosynovitis is now rare, which can delay diagnosis of this disease. We report a case of tenosynovitis of the wrist in a heart transplant patient caused by an isoniazid- and streptomycin-resistant Mycobacterium tuberculosis strain. Despite immunosuppression therapy, which can lead to a smoldering evolution, molecular biology analysis of biopsies allowed a rapid diagnosis.
Le Meur
Alexandre
A
Microbiology Laboratory UPRES-EA 1254, University Hospital, Rennes, France. alexandre.le-meur@chu-rennes.fr
Arvieux
Cédric
C
Guggenbuhl
Pascal
P
Cormier
Michel
M
Jolivet-Gougeon
Anne
A
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000995:Antitubercular Agents / Q000494:pharmacology; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D007538:Isoniazid / Q000494:pharmacology; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000302:isolation & purification*; D013307:Streptomycin / Q000494:pharmacology; D013717:Tenosynovitis / Q000175:diagnosis* / Q000382:microbiology*; D018088:Tuberculosis, Multidrug-Resistant / Q000175:diagnosis* / Q000382:microbiology; D014953:Wrist / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D000995:Antitubercular Agents; D007538:Isoniazid; D013307:Streptomycin