title: Relief of pain in acute herpes zoster by nerve blocks and possible prevention of post-herpetic neuralgia.
abstract: OBJECTIVE
  This report describes two cases of acute herpes zoster (AHZ) treated by nerve block resulting in immediate pain relief and possible prevention of post-herpetic neuralgia (PHN).
  
  
  METHODS
  Two elderly females with AHZ of cervical dermatomes and severe pain received deep cervical and greater occipital nerve blocks with a local anesthetic, epinephrine and steroid. In both patients, pain resolved immediately and permanently (one year follow-up) after a single treatment. Case #1: A 79-yr-old female with a mechanical mitral valve and anticoagulated with warfarin presented with AHZ of 17 days duration of the right C2, 3, 4 dermatomes and severe pain. A stellate ganglion block was not performed because of anticoagulation. Rather, a deep cervical root block at C3 and a greater occipital nerve block were performed with bupivacaine, epinephrine and methylprednisolone. No adverse events were evident. Case #2: A 73-yr-old female with a history of osteoarthritis and Meniere's disease presented with AHZ of seven days duration of the left C2, 3, 4 dermatomes and severe pain. Deep cervical root blocks at C3 and C4 and a greater occipital nerve block were performed with bupivacaine, epinephrine and methylprednisolone. Side effects of dizziness, hoarseness, hypertension and Horner's syndrome resolved in a few hours. A mild sensation of itching persisted for two weeks.
  
  
  CONCLUSIONS
  This report illustrates the potential of nerve blocks in severe AHZ to treat acute pain and possibly prevent PHN.
authors.affiliation: Department of Anesthesiology, The Ottawa Hospital-Civic Campus, 1053 Carling Avenue, Ottawa, Ontario K1Y 4E9, Canada. dhardy@ottawahospital.on.ca
authors.forename: Douglas
authors.initials: D
authors.lastname: Hardy
mesh_terms: D000368:Aged; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D002045:Bupivacaine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D004837:Epinephrine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006562:Herpes Zoster / Q000150:complications*; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D009407:Nerve Block; D009437:Neuralgia / Q000209:etiology / Q000517:prevention & control*; D009802:Oculomotor Nerve; D010146:Pain / Q000188:drug therapy* / Q000209:etiology*; D014662:Vasoconstrictor Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D000779:Anesthetics, Local; D000893:Anti-Inflammatory Agents; D014662:Vasoconstrictor Agents; D008775:Methylprednisolone; D002045:Bupivacaine; D004837:Epinephrine