title: High-yield conversion of (R)-2-octanol from the corresponding racemate by stereoinversion using Candida rugosa.
abstract: Whole cells of Candida rugosa catalyzed the conversion of (R)-2-octanol from the corresponding racemate with the optical purity of 97% e.e. and yield of 92% in 10 h. The product was formed through a stereoinversion involving enantioselective oxidation and asymmetric reduction with 2-octanone as the intermediate.
authors.affiliation: Key Laboratory of Industrial Biotechnology of Ministry of Education & School of Biotechnology, Southern Yangtze University, 214036, Wuxi, P.R. China.
authors.forename: Yao
authors.initials: Y
authors.lastname: Nie
authors.forename: Yan
authors.initials: Y
authors.lastname: Xu
authors.forename: Xiao
authors.initials: X
authors.lastname: Qing Mu
authors.forename: Yan
authors.initials: Y
authors.lastname: Tang
authors.forename: Juan
authors.initials: J
authors.lastname: Jiang
authors.forename: Zhi
authors.initials: Z
authors.lastname: Hao Sun
mesh_terms: D002175:Candida / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D000442:Octanols / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000442:Octanols; C067943:2-octanol