National survey of patients with hemophilia and other congenital bleeding disorders in Thailand.
A national survey of patients with hemophilia and other congenital bleeding disorders in Thailand was conducted in the years 2000 to 2002. Questionnaires were sent to physicians working at hospitals throughout the country. Although the overall response rate to the questionnaires was 19%, the two highest rates of 80% and 73.7% were found at university and regional hospitals, respectively, where most of the patients received their diagnosis and treatment. A total of 1,450 patients comprised of hemophilia 1,325 cases, von Willebrand disease, 69 cases, congenital factor VII deficiency, 15 cases, hereditary platelet dysfunction, 22 cases, and undefined causes of congenital bleeding disorders, 19 cases. Most were pediatric patients <15 years of age. Treatment was mainly given on demand for a bleeding episode, while only 8.6% received additional home treatment for early bleeding episodes. Replacement therapy primarily relied on fresh frozen plasma, cryoprecipitate and cryo-removed plasma. Factor concentrate was seldom used because of the high price. As a result, hemophilia care services in Thailand should be strengthened by providing comprehensive education for medical personnel, making available simple laboratory kits to determine hemophilia A and B, ensuring an adequate supply of blood components and affordable factor concentrate, and establishing home care treatment.
Chuansumrit
Ampaiwan
A
Faculty of Medicine at Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. raajs@mahidol.ac.th
Mahasandana
Chularatana
C
Chinthammitr
Yingyong
Y
Pongtanakul
Boonchu
B
Laossombat
Vichai
V
Nawarawong
Weerasak
W
Lektakul
Yuchinda
Y
Wangruangsatid
Somporn
S
Sriboriboonsin
Ladda
L
Rojnakarin
Ponlapat
P
Angchaisuksiri
Pantep
P
D000293:Adolescent; D025861:Blood Coagulation Disorders, Inherited / Q000453:epidemiology* / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D019538:Health Care Surveys; D006295:Health Resources; D006306:Health Surveys; D006467:Hemophilia A / Q000453:epidemiology* / Q000628:therapy*; D006699:Home Care Services; D006767:Hospitals, District; D006785:Hospitals, University; D006801:Humans; D008297:Male; D017063:Outcome Assessment, Health Care; D015995:Prevalence; D011795:Surveys and Questionnaires; D013785:Thailand / Q000453:epidemiology