Advances in celiac disease.
OBJECTIVE
The number of diagnoses of celiac disease, especially "silent" forms continues to rise world-wide. This review aims to summarize critically recent research in celiac disease.


RESULTS
New proteomic approaches with the development of a possible powerful animal model have potentially furthered the isolation of the epitopes within gliadin, and other related proteins, that are critical for the development of celiac disease.


CONCLUSIONS
The number of potential disease-triggering gliadin components remains large. Small bowel biopsies remain the gold-standard for both diagnosis and monitoring of treatment.
Robins
Gerry
G
Department of Academic Medicine, St. James's University Hospital, Leeds, UK. medggr@leeds.ac.uk
Howdle
Peter D
PD