[The influence of halogenorganic compounds on radiation induced damage of rat eye lens components].
In experiments with white rats the damages of eye lens components of the animals are investigated under combined action of halogenorganic compounds (chloroform and sodium trichloroacetate) and radiation (137Cs) in vivo. It was shown that the injection of these compounds into animals amplifies the radiation-induced oxidation of eye lens components. The effect is manifested in the increase in the content of chromophors with fluorescence in the visible range and products of lipid peroxidation, the decrease in the amount of reduced glutathione. The data support the increased risk of development of radiation-induced cataract in the conditions of tehnogenic pollution of the environment.
Pinchuk
S V
SV
Shukanova
T N
TN
Vadetskaia
T N
TN
Vorobeĭ
A V
AV
D000818:Animals; D002386:Cataract / Q000209:etiology; D002725:Chloroform / Q000633:toxicity; D005720:Gamma Rays; D005978:Glutathione / Q000032:analysis; D006843:Hydrocarbons, Chlorinated / Q000633:toxicity*; D007908:Lens, Crystalline / Q000737:chemistry / Q000187:drug effects* / Q000528:radiation effects*; D015227:Lipid Peroxidation / Q000528:radiation effects; D008297:Male; D011833:Radiation Injuries, Experimental / Q000378:metabolism* / Q000473:pathology; D051381:Rats; D014238:Trichloroacetic Acid / Q000633:toxicity
D006843:Hydrocarbons, Chlorinated; D014238:Trichloroacetic Acid; D002725:Chloroform; D005978:Glutathione