title: [Laryngeal neuroendocrine carcinoma: a case report].
abstract: Laryngeal neuroendocrine carcinomas are uncommon and not well known tumors. Three histological subtypes, each of them with a different prognosis and treatment, can be identified. We report a case of a large cell laryngeal neuroendocrine carcinoma in 32 old-year boy who presented a right glotto-subglottic tumoral process. The patient was treated by total laryngectomy associated with bilateral functional neck dissection but without postoperative chemotherapy. A disease recurrence occured three months after surgery consisting on a massive involvment of laterocervical and sus clavicular lymph nodes. The authors discussed the clinical features, the histological and immunohistochemical characteristics, the treatment and the prognosis of laryngeal neuroendocrine carcinoma, according to literature. (full article translated in English available on www.ent-review.com).
authors.affiliation: CHU Avicenne, Hôpital des Spécialités, Service ORL, Rabat, Maroc.
authors.forename: Y
authors.initials: Y
authors.lastname: Hallaoui
authors.forename: A
authors.initials: A
authors.lastname: El Kohen
authors.forename: S
authors.initials: S
authors.lastname: Sefiani
authors.forename: L
authors.initials: L
authors.lastname: Benchekroun
authors.forename: N
authors.initials: N
authors.lastname: Jazouli
authors.forename: M
authors.initials: M
authors.lastname: Kzadri
mesh_terms: D000328:Adult; D018278:Carcinoma, Neuroendocrine / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery*; D007825:Laryngectomy; D008297:Male; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D016896:Treatment Outcome