title: Tumor necrosis factor receptor-associated periodic syndrome in a young adult who had features of periodic fever, aphthous stomatitis, pharyngitis, and adenitis as a child.
abstract: Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) was diagnosed in a 22-year-old man after a 1-year history of periodic fever, myalgia, conjunctivitis, cervical lymphadenopathy, and oral ulcers. As a child he had signs and symptoms suggestive of periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome. This report indicates the importance of considering TRAPS as a cause of periodic fever in older children and adults and that TRAPS may present with signs and symptoms suggestive of periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome in young children.
authors.affiliation: Department of Pediatrics, University of Virginia Health System, Charlottesville, Virginia 22908, USA.
authors.forename: Frank T
authors.initials: FT
authors.lastname: Saulsbury
authors.forename: Brian
authors.initials: B
authors.lastname: Wispelwey
mesh_terms: D000328:Adult; D002648:Child; D005091:Exons; D005334:Fever / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008199:Lymphadenitis / Q000150:complications; D008297:Male; D009154:Mutation; D010507:Periodicity; D010612:Pharyngitis / Q000150:complications; D018124:Receptors, Tumor Necrosis Factor / Q000235:genetics*; D003294:Seizures, Febrile / Q000209:etiology; D013281:Stomatitis, Aphthous / Q000150:complications; D013577:Syndrome; D014657:Vasculitis / Q000150:complications
chemical_list: D018124:Receptors, Tumor Necrosis Factor