Two new diterpene polyesters from Euphorbia decipiens.
Two new myrsinol-type diterpene polyesters 3,5,13,17-tetra-O-acetyl-7-O-benzoyl-15-hydroxymyrsinol (1) and 3,5,13,17-tetra-O-acetyl-7-O-butanoyl-13-hydroxymyrsinol (2), with a tricyclic carbon skeleton have been isolated from Euphorbia decipiens Boiss. & Buhse. The structure elucidation of the isolated compounds was based primarily on HREIMS, EIMS, IR, UV, ID-, and 2D-NMR analyses, including COSY, HMQC, HMBC, and NOESY correlations. Compounds 1 and 2 also showed activity against urease enzyme.
Ahmad
Viqar Uddin
VU
H.E.J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan. vuahmad@cyber.net.pk
Hussain
Javid
J
Hussain
Hidayat
H
Farooq
Umar
U
Farmanullah
Lodhi
M Arif
MA
Choudhary
M Iqbal
MI
D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D028481:Euphorbia / Q000737:chemistry*; D014510:Urease / Q000037:antagonists & inhibitors
C499962:3,5,13,17-tetra-O-acetyl-7-O-benzoyl-15-hydroxymyrsinol; C499961:3,5,13,17-tetra-O-acetyl-7-O-butanoyl-13-hydroxymyrsinol; D004224:Diterpenes; D004791:Enzyme Inhibitors; D014510:Urease