title: Ultrahigh-resolution optical coherence tomography in glaucoma.
abstract: OBJECTIVE
  Optical coherence tomography (OCT) has been shown to be a valuable tool in glaucoma assessment. We investigated a new ultrahigh-resolution OCT (UHR-OCT) imaging system in glaucoma patients and compared the findings with those obtained by conventional-resolution OCT.
  
  
  METHODS
  Retrospective comparative case series.
  
  
  METHODS
  A normal subject and 4 glaucoma patients representing various stages of glaucomatous damage.
  
  
  METHODS
  All participants were scanned with StratusOCT (axial resolution of approximately 10 mum) and UHR-OCT (axial resolution of approximately 3 microm) at the same visit.
  
  
  METHODS
  Comparison of OCT findings detected with StratusOCT and UHR-OCT.
  
  
  RESULTS
  Ultrahigh-resolution OCT provides a detailed cross-sectional view of the scanned retinal area that allows differentiation between retinal layers. These UHR images were markedly better than those obtained by the conventional-resolution OCT.
  
  
  CONCLUSIONS
  Ultrahigh-resolution OCT provides high-resolution images of the ocular posterior segment, which improves the ability to detect retinal abnormalities due to glaucoma.
authors.affiliation: New England Eye Center, Tufts-New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA.
authors.forename: Gadi
authors.initials: G
authors.lastname: Wollstein
authors.forename: Leila A
authors.initials: LA
authors.lastname: Paunescu
authors.forename: Tony H
authors.initials: TH
authors.lastname: Ko
authors.forename: James G
authors.initials: JG
authors.lastname: Fujimoto
authors.forename: Andrew
authors.initials: A
authors.lastname: Kowalevicz
authors.forename: Ingmar
authors.initials: I
authors.lastname: Hartl
authors.forename: Siobahn
authors.initials: S
authors.lastname: Beaton
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishikawa
authors.forename: Cynthia
authors.initials: C
authors.lastname: Mattox
authors.forename: Omah
authors.initials: O
authors.lastname: Singh
authors.forename: Jay
authors.initials: J
authors.lastname: Duker
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Drexler
authors.forename: Joel S
authors.initials: JS
authors.lastname: Schuman
mesh_terms: D000328:Adult; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D009898:Optic Disk / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D010865:Pilot Projects; D012165:Retinal Ganglion Cells / Q000473:pathology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods*