title: From plants to man: the GPCR "tree of life".
abstract: This Perspective focuses on the article by Fredriksson and Schiöth in the May [corrected] 2005 issue of Molecular Pharmacology. Their article describes the expansion and evolution of G protein-coupled receptors during the nematode-to-chordate split.
authors.affiliation: Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. perezd@ccf.org
authors.forename: Dianne M
authors.initials: DM
authors.lastname: Perez
mesh_terms: D000818:Animals; D006801:Humans; D010802:Phylogeny; D010944:Plants / Q000235:genetics*; D043562:Receptors, G-Protein-Coupled / Q000235:genetics*
chemical_list: D043562:Receptors, G-Protein-Coupled