title: [Danazol effectivity in control of moderate to severe mastalgia].
abstract: BACKGROUND
  Ten percent of women present with moderate to severe mastalgia, and danazol achieves pain relief control with variable results. The objective of this study was to know the success of danazol to control moderate to severe mastalgia.
  
  
  METHODS
  A descriptive, open, transversal and retrospective study (January 2002 to March 2003) was done. Women with moderate to sever mastalgia were studied. Demographic issues, the association of mastalgia with menses, danazol dosage, collateral effects and effectivity of this drug were evaluated for all patients.
  
  
  RESULTS
  Sixty-three patients were studied. Non-cyclic mastalgia occurred in 45 patients (71.4%). Collateral effects presented in 13 patients (20.6%); nausea and irregular menses were the most frequent. Mastalgia control was achieved in 50 patients (79.4%): for cyclic mastalgia 77.7% and for non-cyclic mastalgia 80% (p NS).
  
  
  CONCLUSIONS
  Our results suggest that danazol is a useful drug to control moderate to severe mastalgia.
authors.affiliation: Servicio de Clínica de Mama, Hospital General Tacuba, ISSSTE, Lago Ontario 119, Col. Tacuba, 11410 Mexico DF. cortizmendoza@yahoo.com.mx
authors.forename: Carlos Manuel
authors.initials: CM
authors.lastname: Ortiz-Mendoza
authors.forename: Mónica
authors.initials: M
authors.lastname: Olvera-Mancilla
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001941:Breast Diseases / Q000188:drug therapy*; D003430:Cross-Sectional Studies; D003613:Danazol / Q000008:administration & dosage* / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D004965:Estrogen Antagonists / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D006801:Humans; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy; D010147:Pain Measurement; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D004965:Estrogen Antagonists; D003613:Danazol