2-Arylallyl as a new protecting group for amines, amides and alcohols.
Amines, amides and ethers containing 2-arylallyl groups are selectively and easily deprotected with tert-butyllithium. This transformation probably involves a carbolithiation reaction of the styrenyl moiety followed by a beta-elimination process.
Barluenga
José
J
Instituto Universitario de Quimica Organometalica "Enrique Moles", Unidad Asociada al C.S.I.C. Julian Claveria, 8, Universidad de Oviedo, 33006-Oviedo, Spain. barluenga@uniovi.es
Fañanas
Francisco J
FJ
Sanz
Roberto
R
Marcos
César
C
Ignacio
José M
JM