Alcohol effects on central nervous system gene expression in genetic animal models.
This article summarizes the proceedings of a symposium presented at the 2004 annual meeting of the Research Society on Alcoholism in Vancouver, British Columbia, Canada. The organizers and chairs were William J. McBride and Michael F. Miles. The presentations were (1) Molecular Triangulation on Gene Expression Patterns in Behavioral Responses to Acute Ethanol, by Robnet T. Kerns; (2) Gene Expression in Limbic Regions After Ethanol Self-Infusion Into the Posterior Ventral Tegmental Area, by Zachary A. Rodd; (3) Microarray Analysis of CNS Limbic Regions of Inbred Alcohol-Preferring and -Nonpreferring rats and Effects of Alcohol Drinking, by Wendy N. Strother and Howard J. Edenberg; and (4) Microarray Analysis of Mouse Lines Selected for Chronic Ethanol Withdrawal Severity: The Convergence of Basal, Ethanol Regulated, and Proximity to Ethanol Quantitative Trait Loci to Identify Candidate Genes, by Joel G. Hashimoto and Kristine M. Wiren.
McBride
William J
WJ
Indiana University School of Medicine, Indianapolis, Indiana, USA. wmcbride@iupui.edu
Kerns
Robnet T
RT
Rodd
Zachary A
ZA
Strother
Wendy N
WN
Edenberg
Howard J
HJ
Hashimoto
Joel G
JG
Wiren
Kristine M
KM
Miles
Michael F
MF
D000437:Alcoholism / Q000235:genetics*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects / Q000502:physiology; D002490:Central Nervous System / Q000187:drug effects* / Q000378:metabolism*; D004195:Disease Models, Animal; D005786:Gene Expression Regulation / Q000187:drug effects* / Q000502:physiology; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods / Q000639:trends; D040641:Quantitative Trait Loci; D012720:Severity of Illness Index; D013375:Substance Withdrawal Syndrome / Q000235:genetics