Role of [18F]-dopa-PET imaging in assessing movement disorders.
FD-PET has proved to be an extremely useful technique for the noninvasive evaluation of nigrostriatal pathophysiology in patients with PD and other movement disorders. The development of ratio methods for image analysis has greatly reduced the complexity of these PET studies and has facilitated data analysis. With the recent advances in cyclotron targetry and automated synthesis modules FD-PET will soon become an important component of the clinical armamentarium.
Fischman
Alan J
AJ
Division of Nuclear Medicine, Department of Radiology, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA. fischman@pet.mgh.harvard.edu
D004295:Dihydroxyphenylalanine / Q000031:analogs & derivatives*; D018491:Dopamine Agonists / Q000627:therapeutic use; D005462:Fluorine Radioisotopes; D006801:Humans; D010300:Parkinson Disease / Q000000981:diagnostic imaging* / Q000188:drug therapy; D049268:Positron-Emission Tomography
D018491:Dopamine Agonists; D005462:Fluorine Radioisotopes; C043437:fluorodopa F 18; D004295:Dihydroxyphenylalanine