[Periconceptional supplementation with folic acid for the primary prevention of congenital malformations].
Most international trials support the recommendation that all women planning or at risk of pregnancy take a daily multivitamin supplement containing folic acid, beginning one month before conception and continuing through the first trimester for primary prevention of neural tube defects and other congenital malformations. Recently an intervention project started also in Italy, in order to support and maintain the periconceptional supplementation and to evaluate the efficacy of a national preventive campaign on parents' behaviour.
Ronfani
L
L
Centro per la Salute del Bambino, Trieste.
Marchetti
E
E
Bortolus
R
R
D'Andrea
N
N
Taccardi
R
R
Annona
C
C
Ghiotti
P
P
Mastroiacovo
P
P
Tamburlini
G
G
D000328:Adult; D002986:Clinical Trials as Topic; D000013:Congenital Abnormalities / Q000517:prevention & control*; D005260:Female; D005492:Folic Acid / Q000008:administration & dosage*; D005494:Folic Acid Deficiency / Q000517:prevention & control*; D006801:Humans; D007231:Infant, Newborn; D007558:Italy; D009436:Neural Tube Defects / Q000517:prevention & control; D010290:Parents; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011322:Primary Prevention; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D013997:Time Factors
D005492:Folic Acid