title: Adrenocortical carcinoma arising from a long-standing adrenal mass.
abstract: Adrenocortical carcinoma is a rare tumor with a dismal prognosis. In stark contrast, benign incidental adrenal lesions are detected commonly on routine abdominal imaging. We report a case of a 74-year-old man with a history of germ cell testicular carcinoma who presented with a 4.8-cm left adrenal lesion. The lesion remained stable for 8 years, at which time the patient became symptomatic from an excess of cortisol hormone. Biopsy findings confirmed adrenocortical carcinoma. We describe the presentation, clinical findings, diagnostic work-up, and follow-up of this patient and review the literature.
authors.affiliation: Department of General Surgery, Wake Forest University of Health Sciences, Winston-Salem, NC, USA.
authors.forename: Kattron R
authors.initials: KR
authors.lastname: Cofield
authors.forename: Larry K
authors.initials: LK
authors.lastname: Cantley
authors.forename: Kim R
authors.initials: KR
authors.lastname: Geisinger
authors.forename: Ron J
authors.initials: RJ
authors.lastname: Zagoria
authors.forename: Nancy D
authors.initials: ND
authors.lastname: Perrier
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000473:pathology*; D018268:Adrenocortical Carcinoma / Q000473:pathology*; D000368:Aged; D002471:Cell Transformation, Neoplastic; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D013997:Time Factors