title: Effect of early initiation of statins on survival in patients with acute myocardial infarction (the USIC 2000 Registry).
abstract: We evaluated the association of statin initiation within 48 hours of admission for an acute myocardial infarction with a 1-year prognosis on a nationwide scale. Patients who received a statin within 48 hours of admission but not before hospitalization had an improved prognosis (hazard ratio 0.57, 95% confidence interval 0.38 to 0.86, p <0.007) after adjustment for covariates and propensity score.
authors.affiliation: Department of Epidemiology, INSERM U558, Toulouse, France. jean.ferrieres@cict.fr
authors.forename: Jean
authors.initials: J
authors.lastname: Ferrières
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Cambou
authors.forename: Pascal
authors.initials: P
authors.lastname: Guéret
authors.forename: Youcef
authors.initials: Y
authors.lastname: Boutalbi
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Lablanche
authors.forename: Guy
authors.initials: G
authors.lastname: Hanania
authors.forename: Nathalie
authors.initials: N
authors.lastname: Genès
authors.forename: Christelle
authors.initials: C
authors.lastname: Cantet
authors.forename: Nicolas
authors.initials: N
authors.lastname: Danchin
mesh_terms: D000368:Aged; D005260:Female; D005602:France / Q000453:epidemiology; D006760:Hospitalization; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage*; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000401:mortality*; D011379:Prognosis; D016016:Proportional Hazards Models; D012042:Registries; D013997:Time Factors
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors