Disseminated strongyloidiasis successfully treated with extended duration ivermectin combined with albendazole: a case report of intractable strongyloidiasis.
We describe a patient with an overlapping syndrome disseminated strongyloidiasis and gram-negative sepsis. She was previously treated with albendazole 400 mg/day 14 days before admission without success. This admission, she was treated with a combination of oral ivermectin (injectable solution form), with a dosage of 200-400 microg/kg/day, and albendazole for 14 days. Strongyloides larvae disappeared from the stool by day 4 and from the sputum by day 10. No side effects were encountered during hospitalization or at the 1-month follow-up visit.
Pornsuriyasak
Prapaporn
P
Faculty of Medicine at Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Niticharoenpong
Kannika
K
Sakapibunnan
Atipoom
A
D015766:Albendazole / Q000627:therapeutic use*; D000818:Animals; D000871:Anthelmintics / Q000600:supply & distribution / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy; D007559:Ivermectin / Q000600:supply & distribution / Q000627:therapeutic use*; D007814:Larva / Q000469:parasitology; D008875:Middle Aged; D010270:Parasite Egg Count; D018805:Sepsis / Q000150:complications / Q000188:drug therapy; D017171:Strongyloides stercoralis / Q000187:drug effects*; D013322:Strongyloidiasis / Q000097:blood / Q000188:drug therapy* / Q000652:urine; D013785:Thailand; D016896:Treatment Outcome; D014657:Vasculitis / Q000150:complications
D000871:Anthelmintics; D007559:Ivermectin; D015766:Albendazole