title: A phase I and pharmacokinetic study of short infusions of UCN-01 in patients with refractory solid tumors.
authors.affiliation: Division of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans Street, Baltimore, MD 21231, USA.
authors.forename: E Claire
authors.initials: EC
authors.lastname: Dees
authors.forename: Sharyn D
authors.initials: SD
authors.lastname: Baker
authors.forename: Seamus
authors.initials: S
authors.lastname: O'Reilly
authors.forename: Michelle A
authors.initials: MA
authors.lastname: Rudek
authors.forename: Susan B
authors.initials: SB
authors.lastname: Davidson
authors.forename: Cheryl
authors.initials: C
authors.lastname: Aylesworth
authors.forename: Kathy
authors.initials: K
authors.lastname: Elza-Brown
authors.forename: Michael A
authors.initials: MA
authors.lastname: Carducci
authors.forename: Ross C
authors.initials: RC
authors.lastname: Donehower
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000493:pharmacokinetics*; D004305:Dose-Response Relationship, Drug; D019008:Drug Resistance, Neoplasm; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D020714:Maximum Tolerated Dose; D008875:Middle Aged; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology; D011493:Protein Kinase C / Q000037:antagonists & inhibitors; D016879:Salvage Therapy; D019311:Staurosporine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000493:pharmacokinetics*; D013997:Time Factors
chemical_list: D000970:Antineoplastic Agents; C054852:7-hydroxystaurosporine; D011493:Protein Kinase C; D019311:Staurosporine