title: Cerebrovascular abnormalities in a population of children with neurofibromatosis type 1.
abstract: Neurofibromatosis type 1 (NF1) is associated with vasculopathy, which may result in a variety of cerebrovascular complications. The purpose of this study was to evaluate the spectrum of cerebrovascular disease in a pediatric population with NF1. Of 316 patients with NF1 who underwent brain MRI, 8 (2.5%) children were reported to have an abnormality of the cerebrovascular system, including narrowed or ectatic vessels, vascular stenoses, aneurysm, and moyamoya.
authors.affiliation: Department of Neurology, Center for Neuroscience and Behavioral Medicine, Children's National Medical Center, The George Washington University, 111 Michigan Avenue NW, Washington, DC 20010, USA. trosser@cnmc.org
authors.forename: Tena L
authors.initials: TL
authors.lastname: Rosser
authors.forename: Gilbert
authors.initials: G
authors.lastname: Vezina
authors.forename: Roger J
authors.initials: RJ
authors.lastname: Packer
mesh_terms: D000293:Adolescent; D016893:Carotid Stenosis / Q000209:etiology / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D004108:Dilatation, Pathologic / Q000209:etiology / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D021621:Imaging, Three-Dimensional; D007223:Infant; D020244:Infarction, Middle Cerebral Artery / Q000209:etiology / Q000473:pathology*; D002532:Intracranial Aneurysm / Q000209:etiology / Q000473:pathology*; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D009072:Moyamoya Disease / Q000209:etiology / Q000473:pathology*; D009456:Neurofibromatosis 1 / Q000150:complications / Q000473:pathology*; D010291:Paresis / Q000209:etiology; D012189:Retrospective Studies