[Isolation and structure identification of C-25 epimers of inokosterone from Achyranthes bidentata Blume].
OBJECTIVE
To isolate C-25 epimers of inokosterone from Achyranthes bidentata Blume. and identify their structures.


METHODS
To separate C-25 epimers of inokosterone by using various kinds of chromatography methods and identify their structures on basis of spectral analysis and chemical method.


RESULTS
Three compounds were isolated and their structures were established as 25S-inokosterone (1), 25R-inokosterone (2) and ecdysterone (3).


CONCLUSIONS
Compounds 1 and 2 are new C-25 configuration isomers from Achyranthes bidentata Blume., their absolute configurations are elucidated at the first time, and their 13CNMR data are reported for the first time.
Zhu
Ting-Ting
TT
Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing 100083, China.
Liang
Hong
H
Zhao
Yu-Ying
YY
Wang
Ben
B
D029044:Achyranthes / Q000737:chemistry*; D002782:Cholestenes / Q000737:chemistry / Q000302:isolation & purification*; D004441:Ecdysterone / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013237:Stereoisomerism
D002782:Cholestenes; C100084:inokosterone; D004441:Ecdysterone