title: Cutaneous Waldenstrom's macroglobulinemia with "deck-chair" sign treated with cyclophosphamide.
abstract: Specific skin lesions are rare in Waldenstrom's macroglobulinemia (WM). We report a case of a 58-year-old man who presented macules, papules, and an erythema of the trunk with the "deck-chair" sign revealing the relapse of WM. Histologic and immunohistochemical examinations confirmed that cutaneous lesions were related to specific infiltration with neoplastic cells. Remission of both skin lesions and immunological abnormalities was obtained with oral cyclophosphamide.
authors.affiliation: Departments of Dermatology, Hôpital Tarnier-Cochin, Paris, France.
authors.forename: Julien
authors.initials: J
authors.lastname: Autier
authors.forename: Marc
authors.initials: M
authors.lastname: Buffet
authors.forename: Laure
authors.initials: L
authors.lastname: Pinquier
authors.forename: Anne-Isabelle
authors.initials: AI
authors.lastname: Merlat-Guitard
authors.forename: Agnes
authors.initials: A
authors.lastname: Carlotti
authors.forename: Nathalie
authors.initials: N
authors.lastname: Franck
authors.forename: Isabelle
authors.initials: I
authors.lastname: Gorin
authors.forename: Nicolas
authors.initials: N
authors.lastname: Dupin
mesh_terms: D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012871:Skin Diseases / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology*; D008258:Waldenstrom Macroglobulinemia / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology*
chemical_list: D018906:Antineoplastic Agents, Alkylating; D003520:Cyclophosphamide