title: Fluorescence studies of the intra-cellular distribution of zinc bis(thiosemicarbazone) complexes in human cancer cells.
abstract: The uptake of zinc bis(thiosemicarbazone) complexes in human cancer cells has been studied by fluorescence microscopy and the cellular distribution established, including the degree of uptake in the nucleus.
authors.affiliation: Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, UKOX1 3TA.
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Cowley
authors.forename: Jason
authors.initials: J
authors.lastname: Davis
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Dilworth
authors.forename: Paul S
authors.initials: PS
authors.lastname: Donnelly
authors.forename: Rachel
authors.initials: R
authors.lastname: Dobson
authors.forename: Adrian
authors.initials: A
authors.lastname: Nightingale
authors.forename: Josephine M
authors.initials: JM
authors.lastname: Peach
authors.forename: Ben
authors.initials: B
authors.lastname: Shore
authors.forename: David
authors.initials: D
authors.lastname: Kerr
authors.forename: Len
authors.initials: L
authors.lastname: Seymour
mesh_terms: D045744:Cell Line, Tumor; D006801:Humans; D008856:Microscopy, Fluorescence / Q000379:methods; D008958:Models, Molecular; D009942:Organometallic Compounds / Q000737:chemistry / Q000493:pharmacokinetics*; D012680:Sensitivity and Specificity; D013329:Structure-Activity Relationship; D013882:Thiosemicarbazones / Q000737:chemistry / Q000493:pharmacokinetics*; D014018:Tissue Distribution; D015032:Zinc / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D013882:Thiosemicarbazones; D015032:Zinc