Antinociceptive effect of Teucrium polium leaf extract in the diabetic rat formalin test.
This study was designed to evaluate the analgesic effect of Teucrium polium leaf extract in the diabetic rat formalin test. For this purpose, streptozotocin (STZ)-diabetic rats received intraperitoneal injection of this extract (100 and 200 mg/kg per day) for a period of 2 weeks. It was found out that Teucrium polium-treated diabetic rats exhibited a lower nociceptive score as compared to untreated diabetics. The results may suggest therapeutic potential of Teucrium polium extract for the treatment of diabetic hyperalgesia.
Baluchnejadmojarad
Tourandokht
T
Department of Physiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Roghani
Mehrdad
M
Roghani-Dehkordi
Farshad
F
D000700:Analgesics / Q000302:isolation & purification / Q000627:therapeutic use*; D000818:Animals; D001786:Blood Glucose / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D003921:Diabetes Mellitus, Experimental; D005557:Formaldehyde / Q000633:toxicity; D008297:Male; D010146:Pain / Q000139:chemically induced / Q000188:drug therapy*; D008517:Phytotherapy; D010936:Plant Extracts / Q000302:isolation & purification / Q000627:therapeutic use*; D018515:Plant Leaves; D051381:Rats; D017208:Rats, Wistar; D031367:Teucrium
D000700:Analgesics; D001786:Blood Glucose; D010936:Plant Extracts; C040618:teucrium extract; D005557:Formaldehyde