Benign fibrous histiocytoma of the mandible.
A very rare case of benign fibrous histiocytoma of the mandible is presented. A 49-year-old woman was admitted because of left buccal swelling and pain. Panoramic radiograph showed well-demarcated soap-bubble appearance without sclerotic rim in the left mandibular bone. A yellowish-white and partly brown solid tumor was noted in the excised mandibular bone specimen. The tumor histologically consisted of spindle cells, in which areas showing a storiform pattern and other areas composed of histiocytic cells with erythrophagocytosis and foam cells were mixed. Immunohistochemically, the tumor cells were positive for vimentin, CD68, alpha-1-antichymotrypsin and alpha-1-antitrypsin. From these findings the tumor was diagnosed as a primary BFH of the mandible. No recurrence has been noted 2 years and 11 months after surgery.
Kishino
Mitsunobu
M
Department of Oral Pathology, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan.
Murakami
Shumei
S
Toyosawa
Satoru
S
Nakatani
Atsutoshi
A
Ogawa
Yuzo
Y
Ishida
Takeshi
T
Ijuhin
Naokuni
N
D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D005260:Female; D005487:Foam Cells / Q000473:pathology; D005500:Follow-Up Studies; D006644:Histiocytes / Q000473:pathology; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology*; D006801:Humans; D008264:Macrophages / Q000473:pathology; D008339:Mandibular Neoplasms / Q000473:pathology*; D008875:Middle Aged; D010587:Phagocytosis; D011862:Radiography, Panoramic; D014746:Vimentin / Q000032:analysis; D000514:alpha 1-Antichymotrypsin / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D014746:Vimentin; D000514:alpha 1-Antichymotrypsin; D000515:alpha 1-Antitrypsin; C067980:CD68 antigen, human; D000097382:CD68 Molecule