title: Totally subcutaneous hemodialysis access: experience with the LifeSite Hemodialysis System.
abstract: The LifeSite Hemodialysis System (Vasca, Inc., Tewksbury, MA) is totally subcutaneous, incorporating two silicone catheters positioned in the central venous system and connected to a stainless steel-titanium valve implanted in a subcutaneous pocket. A randomized trial and nonrandomized clinical experience have demonstrated lower rates of infection and longer device survival when 70% isopropyl alcohol is used as the antimicrobial solution with the LifeSite. Internal jugular vein placement with positioning of the valve on the anterior chest wall further improves results.
authors.affiliation: Jobst Vascular Center, Toledo, OH, USA. acomerota@jvc.org
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Comerota
mesh_terms: D019840:2-Propanol / Q000627:therapeutic use; D001783:Blood Flow Velocity / Q000502:physiology; D002405:Catheterization, Central Venous / Q000009:adverse effects / Q000379:methods*; D048909:Diabetes Complications / Q000150:complications; D004867:Equipment Design; D006801:Humans; D007601:Jugular Veins / Q000601:surgery; D007676:Kidney Failure, Chronic / Q000628:therapy; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000517:prevention & control; D006435:Renal Dialysis / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D012828:Silicones; D017211:Treatment Failure
chemical_list: D012828:Silicones; D019840:2-Propanol