Levetiracetam in the treatment of infantile spasms.
An 11-month-old infant with a 5-month history of seizures and a 3-month history of infantile spasms is described. EEG showed epileptic encephalopathy. The infantile spasms were resistant to treatment with clobazam. Following the introduction of levetiracetam, there was clinical cessation of seizures with resolution of seizure activity on the EEG. This is the second report in the literature of effective treatment of infantile spasms with levetiracetam.
Lawlor
Katherine M
KM
Department of Paediatric Neurology, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE, UK.
Devlin
Anita M
AM
D000927:Anticonvulsants / Q000627:therapeutic use*; D004569:Electroencephalography; D006801:Humans; D007223:Infant; D000077287:Levetiracetam; D008297:Male; D010889:Piracetam / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D013036:Spasms, Infantile / Q000188:drug therapy* / Q000503:physiopathology
D000927:Anticonvulsants; D000077287:Levetiracetam; D010889:Piracetam