Sodium transport in airway epithelium correlates with lung compliance in healthy newborn infants.
To study the relation between sodium transport in airway epithelium and postnatal pulmonary adaptation, we measured nasal potential difference at 1 to 4 hours and lung compliance at 21 to 48 hours after birth in 20 healthy infants. Sodium transport correlated with lung compliance ( r 2 = 0.40, P < .003). Airway sodium transport plays a role in postnatal pulmonary adaptation.
Helve
Otto
O
Department of Neonatology, Hospital for Children and Adolescents, Helsinki University Central Hospital, 00029-HUS, Helsinki, Finland.
Pitkänen
Olli
O
Kirjavainen
Turkka
T
Andersson
Sture
S
D004847:Epithelial Cells / Q000378:metabolism; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D017136:Ion Transport; D008170:Lung Compliance / Q000502:physiology*; D008297:Male; D020545:Respiratory Mucosa / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism* / Q000493:pharmacokinetics
D012964:Sodium