One-pot four-component reaction: aqueous TiCl3/PhN2+-mediated alkyl radical addition to imines generated in situ.
Ti(III)-induced free-radical decomposition of a phenyldiazonium salt, followed by phenyl radical iodine-atom abstraction from alkyl iodides, leads to a one-pot selective alkyl radical addition to the C-atom of imines generated in situ under aqueous acidic conditions. [reaction: see text]
Cannella
Rosalba
R
Dipartimento di Chimica, Materiali e Ingegneria Chimica Giulio Natta, Politecnico di Milano-Sezione Chimica, Via Mancinelli 7, 20131 Milan, Italy.
Clerici
Angelo
A
Pastori
Nadia
N
Regolini
Eva
E
Porta
Ombretta
O