[Treatment of frontotemporal dementia].
Frontotemporal dementia (FTD) is the most neglected dementia by pharmacological research. Nevertheless, FTD can be now diagnosed with a good accuracy. Serotonin deficit is found in FTD and most of FTD are tauopathies. Pharmacological agents such as trazodone have showed a positive effect on behavioral symptoms, but the cognitive symptoms can not be significantly improved and parameters to follow a long-term trial in FTD remain to be identified. The recognition of the differences between FTD and Alzheimer's disease allows to determine a specific management of FTD patients and their caregivers.
Lebert
Florence
F
Centre de la mémoire, Hôpital Salengro, CHRU Lille. f-lebert@chru-lille.fr
D000544:Alzheimer Disease / Q000175:diagnosis; D003072:Cognition Disorders / Q000209:etiology; D003704:Dementia / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D003937:Diagnosis, Differential; D006801:Humans; D008996:Monoamine Oxidase Inhibitors / Q000627:therapeutic use*; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*
D008996:Monoamine Oxidase Inhibitors; D017367:Selective Serotonin Reuptake Inhibitors