Paraneoplastic limbic encephalitis--case report and review of literature.
We report a 77-year old man who presented with a sub-acute dementia associated with aggressive behaviour, ataxia, rapid progression and death. No cause for his illness could be detected in his lifetime, but at post mortem he was found to have paraneoplastic limbic encephalitis and a bronchogenic tumour. A diagnosis of paraneoplastic limbic encephalitis should be considered in the differential diagnosis of unexplained dementias and appropriate investigations performed to diagnose the condition.
Munshi
Sunil K
SK
Department of Cerebrovascular Medicine & Medicine for the Elderly, Leicester General Hospital, University Hospital of Leicester, Gwendolen Road, Leicester LE5 4PW, UK. sunil.munshi@uhl-tr.nhs.uk
Thanvi
Bhomraj
B
Chin
Su Kiun
SK
Hubbard
Irene
I
Fletcher
Alan
A
Vallance
Tony R
TR
D000368:Aged; D001921:Brain / Q000473:pathology; D018288:Carcinoma, Small Cell / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D020363:Limbic Encephalitis / Q000175:diagnosis* / Q000473:pathology; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male