title: Mitral valve morphology and morbidity/mortality in Shone's complex.
abstract: Early echocardiographic studies of 50 patients with Shone's complex were retrospectively examined to identify left-sided cardiac features associated with progressive mitral valve (MV) disease requiring intervention, as well as mortality. Thickened MV leaflets, shortened MV chordae coupled with either thickened MV leaflets or turbulence at or below the MV noted by color Doppler, left ventricular outflow tract obstruction without coarctation of the aorta, and mild or moderate aortic insufficiency were associated with a poor prognosis.
authors.affiliation: University of Texas Southwestern, Children's Medical Center of Dallas, Division of Cardiology, Dallas, Texas, USA. catherine.ikemba@childrens.com
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Ikemba
authors.forename: Benjamin W
authors.initials: BW
authors.lastname: Eidem
authors.forename: J Kennard
authors.initials: JK
authors.lastname: Fraley
authors.forename: Reenu S
authors.initials: RS
authors.lastname: Eapen
authors.forename: Ricardo
authors.initials: R
authors.lastname: Pignatelli
authors.forename: Nancy A
authors.initials: NA
authors.lastname: Ayres
authors.forename: Louis I
authors.initials: LI
authors.lastname: Bezold
mesh_terms: D002648:Child; D002675:Child, Preschool; D018618:Echocardiography, Doppler, Color; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging / Q000401:mortality* / Q000628:therapy; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008943:Mitral Valve / Q000002:abnormalities* / Q000000981:diagnostic imaging* / Q000601:surgery; D011379:Prognosis; D012189:Retrospective Studies; D013781:Texas / Q000453:epidemiology; D014694:Ventricular Outflow Obstruction / Q000000981:diagnostic imaging / Q000401:mortality* / Q000628:therapy