Intercellular communications induced by random fluctuations.
This paper investigates a general coupled noisy system for a cell-cell communication in a multi-cell system. The main conclusion is that appropriate noise intensity and coupling strength are capable of driving the coupled system to synchrony, which may be exploited by biological organisms to actively facilitate mutual communication. A multi-cell system with a synthetic gene network with both noises and delays is adopted to demonstrate the effect of noises on cellular communication.
Zhou
Tianshou
T
Tsinghua University, Beijing 100084, China. tszhou@math.tsinghua.edu.cn
Chen
Luonan
L
Wang
Ruiqi
R
Aihara
Kazuyuki
K
D000222:Adaptation, Physiological / Q000502:physiology; D002450:Cell Communication / Q000502:physiology*; D003198:Computer Simulation; D005786:Gene Expression Regulation / Q000502:physiology*; D008954:Models, Biological; D015233:Models, Statistical; D015398:Signal Transduction / Q000502:physiology*; D013269:Stochastic Processes