title: Pulmonary hypertension during epileptic seizure with evidence of increased angiotensin II in pulmonary artery.
abstract: We experienced a 78-year-old man in whom transient pulmonary hypertension was documented during epileptic seizure. A Swan-Ganz catheter demonstrated that pulmonary arterial pressure rose immediately after the initiation of the seizure, which was followed by systemic hypertension. The plasma level of angiotensin II increased in pulmonary circulation during the seizures; however, catecholamines did not change from the baseline. The patient responded well to treatment with an antiepileptic drug and losartan potassium.
authors.affiliation: Department of Cardiology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
authors.forename: Yoko
authors.initials: Y
authors.lastname: Ueno
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takagi
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kawana
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kasanuki
mesh_terms: D000368:Aged; D000804:Angiotensin II / Q000097:blood / Q000378:metabolism*; D000927:Anticonvulsants / Q000627:therapeutic use; D002407:Catheterization, Swan-Ganz; D004359:Drug Therapy, Combination; D004827:Epilepsy / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D005500:Follow-Up Studies; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D019808:Losartan / Q000627:therapeutic use; D008297:Male; D011651:Pulmonary Artery; D011652:Pulmonary Circulation / Q000502:physiology; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants; D000804:Angiotensin II; D019808:Losartan