title: Bone compaction enhances fixation of weightbearing titanium implants.
abstract: Implant stability is crucial for implant survival. A new surgical technique, compaction, has increased in vitro implant stability and in vivo fixation of nonweightbearing implants. However, the in vivo effects of compaction on weightbearing implants are unknown. As implants inserted clinically are weightbearing, the effects of compaction on weightbearing implants were examined. The hypothesis was that compaction would increase implant fixation compared with conventional drilling. Porous-coated titanium implants were inserted bilaterally into the weightbearing portion of the femoral condyles of dogs. In each dog, one knee had the implant cavity prepared with drilling, and the other knee was prepared with compaction. Eight dogs were euthanized after 2 weeks, and eight dogs were euthanized after 4 weeks. Femoral condyles from an additional eight dogs represented Time 0. Compacted specimens had higher bone-implant contact and periimplant bone density at 0 and 2 weeks, but not at 4 weeks. A biphasic response of compaction was found with a pushout test, as compaction increased ultimate shear strength and energy absorption at 0 and 4 weeks, but not at 2 weeks. This biphasic response indicates that compaction enhances implant fixation by mechanical and biological mechanisms. Therefore, compaction might have potential value in total joint replacement in the future.
authors.affiliation: Orthopaedic Research Laboratory, Department of Orthopaedics, Aarhus University Hospital, Nørrebrogade 44, Bldg., 1A, DK-8000 Aarhus C, Denmark. s.kold@dadlnet.dk
authors.forename: Søren
authors.initials: S
authors.lastname: Kold
authors.forename: Ole
authors.initials: O
authors.lastname: Rahbek
authors.forename: Marianne
authors.initials: M
authors.lastname: Vestermark
authors.forename: Søren
authors.initials: S
authors.lastname: Overgaard
authors.forename: Kjeld
authors.initials: K
authors.lastname: Søballe
mesh_terms: D000818:Animals; D015519:Bone Density; D004285:Dogs; D005260:Female; D007595:Joint Prosthesis; D008297:Male; D013314:Stress, Mechanical; D014025:Titanium; D016474:Weight-Bearing
chemical_list: D014025:Titanium