title: Is the periprostatic anesthetic blockade advantageous in ultrasound-guided prostate biopsy?
abstract: OBJECTIVE
  To assess the benefit of the periprostatic administration of lidocaine previously to ultrasound-guided prostate biopsy.
  
  
  METHODS
  In the period from April to October 2002, forty patients underwent ultrasound-guided prostate biopsy due to increased PSA or abnormal digital rectal examination. A randomized double-blind study was performed, where the patients received an injection of lidocaine 2% or saline solution, in a total of 10 ml periprostatic. Immediately following the biopsy, the pain associated to the procedure was assessed, using a visual analogical scale from 0 to 10. The mean number of fragments collected per patient in the biopsies was 11.3. The statistical analysis used for assessment of pain was the Student's t, with p < 0.05 being significant.
  
  
  RESULTS
  The groups were homogeneous concerning the anthropometrical data. In relation to pain, those patients in the groups that underwent biopsy with the use of lidocaine presented a maximum score of 6, while in the group that underwent biopsy with the use of saline solution, 4 patients presented score 7 ou 8. The mean score and standard deviation with lidocaine were 2.55 +/- 2.34 (CI 95% = 1.53 to 3.57) and with saline solution were 3.75 +/- 2.52 (CI 95% = 2.66 +/- 4.84) with no statistical significant difference between the groups.
  
  
  CONCLUSIONS
  The lidocaine injection did not show statistical difference when compared with saline solution in the periprostatic blockade during echo-guided prostate biopsy.
authors.affiliation: Division of Urology, Amaral Carvalho Hospital, Jaú, São Paulo, Brazil. vanni@flash.jau.tv.br
authors.forename: André P
authors.initials: AP
authors.lastname: Vanni
authors.forename: Carlos H
authors.initials: CH
authors.lastname: Schaal
authors.forename: Renato P
authors.initials: RP
authors.lastname: Costa
authors.forename: Fernando C
authors.initials: FC
authors.lastname: Sala
mesh_terms: D000368:Aged; D000772:Anesthesia, Local; D000779:Anesthetics, Local / Q000008:administration & dosage*; D001707:Biopsy, Needle / Q000009:adverse effects; D004311:Double-Blind Method; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D011467:Prostate / Q000000981:diagnostic imaging / Q000473:pathology*; D018084:Ultrasonography, Interventional
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine