Cutaneous Waldenstrom's macroglobulinemia with "deck-chair" sign treated with cyclophosphamide.
Specific skin lesions are rare in Waldenstrom's macroglobulinemia (WM). We report a case of a 58-year-old man who presented macules, papules, and an erythema of the trunk with the "deck-chair" sign revealing the relapse of WM. Histologic and immunohistochemical examinations confirmed that cutaneous lesions were related to specific infiltration with neoplastic cells. Remission of both skin lesions and immunological abnormalities was obtained with oral cyclophosphamide.
Autier
Julien
J
Departments of Dermatology, Hôpital Tarnier-Cochin, Paris, France.
Buffet
Marc
M
Pinquier
Laure
L
Merlat-Guitard
Anne-Isabelle
AI
Carlotti
Agnes
A
Franck
Nathalie
N
Gorin
Isabelle
I
Dupin
Nicolas
N
D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012871:Skin Diseases / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology*; D008258:Waldenstrom Macroglobulinemia / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology*
D018906:Antineoplastic Agents, Alkylating; D003520:Cyclophosphamide