title: Intra-arterial vasopressin injection for the treatment of massive bleeding from the external carotid artery after craniofacial trauma--technical note.
abstract: Vasopressin (0.8-1.0 IU), diluted with saline (10 IU vasopressin per 100 ml saline), was selectively injected into the external carotid artery (ECA) to control massive hemorrhage caused by inaccessible serious craniofacial injuries in two patients. This method produced remarkable angiographic vasoconstriction at the involved ECA branches and resulted in immediate hemostasis. Intra-arterial vasopressin injection is a useful option for the treatment of intractable traumatic hemorrhage from inaccessible ECA branches.
authors.affiliation: Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan. yokada@twmu.ac.jp
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Okada
authors.forename: Takashi
authors.initials: T
authors.lastname: Higa
authors.forename: Tomokatsu
authors.initials: T
authors.lastname: Hori
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shima
authors.forename: Akira
authors.initials: A
authors.lastname: Yoshida
mesh_terms: D000328:Adult; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D002342:Carotid Artery, External / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D020202:Cerebral Hemorrhage, Traumatic / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D005151:Facial Injuries / Q000150:complications; D005260:Female; D006490:Hemostatics / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D007269:Injections, Intra-Arterial; D008437:Maxilla / Q000293:injuries; D008875:Middle Aged; D009777:Occipital Bone / Q000293:injuries; D012887:Skull Fractures / Q000150:complications / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014667:Vasopressins / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D006490:Hemostatics; D014667:Vasopressins