title: Multilayer modeling of reflectance pulse oximetry.
abstract: A multilayer tissue description was employed in Monte Carlo simulations of reflectance pulse oximetry to study the impact of assumptions made in previous studies employing homogeneous tissue models. Simulation results with a discrete layer of arterial pulsatility were similar to previous studies employing homogenous tissue models. However, the relationship of normalized pulse amplitude to emitter-detector spacing reiterates that spacing has a significant impact on pulse oximetry function. The effect of melanin content as a thin, superficial absorber was also simulated, with results supporting the general clinical observation that skin shade need not substantially compromise pulse oximeter accuracy.
authors.affiliation: OB Scientific, Inc, Germantown, WI 53022, USA. jim.reuss@obscientific.com
authors.forename: James L
authors.initials: JL
authors.lastname: Reuss
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D005323:Fetal Monitoring / Q000379:methods*; D006801:Humans; D008543:Melanins / Q000502:physiology*; D008955:Models, Cardiovascular; D015233:Models, Statistical; D010092:Oximetry / Q000379:methods*; D010100:Oxygen / Q000097:blood*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012879:Skin Physiological Phenomena; D041622:Tomography, Optical / Q000379:methods
chemical_list: D008543:Melanins; D010100:Oxygen