title: Urinary tract infections in unplanned pregnancies and fetal outcome.
abstract: OBJECTIVE
  Many pregnant women are exposed to antibiotics for urinary tract infections during pregnancy. Our aim is to bring attention to antibiotherapy in unplanned pregnancies.
  
  
  METHODS
  Among the 511 cases followed by our 'Toxicology Information and Follow-up Service' for drug exposure during pregnancy, 101 cases, unaware of their pregnancy, had been prescribed antibiotics and urinary antiseptic drugs in the first trimester of their unplanned pregnancies. The data on the outcome of these pregnancies and the babies were evaluated in this study.
  
  
  RESULTS
  Of the 511 cases, 101 pregnant women were exposed to nine kinds of drugs. Seventy-five cases had healthy babies; two had babies with major malformations; one had a baby with congenital hypothyroidism; five had spontaneous abortions; and eight cases underwent induced abortions. The outcomes of eight pregnancies are unknown. Two pregnancies are still continuing without any problem. One baby had a fetal renal anomaly; however, the physical examination did not reveal any other malformations. The baby died 4 hours after delivery. Another baby had atrial septal defect, a major malformation, and one baby had congenital hypothyroidism.
  
  
  CONCLUSIONS
  Urinary tract infection is one of the most frequently seen complications of pregnancy. Our study indicated that the possibility of pregnancy should be considered when prescribing antibiotics for urinary tract infections in women of reproductive age.
authors.affiliation: Department of Family Medicine, Karadeniz Technical University, School of Medicine, Trabzon, Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Yaris
authors.forename: M
authors.initials: M
authors.lastname: Kadioglu
authors.forename: M
authors.initials: M
authors.lastname: Kesim
authors.forename: M
authors.initials: M
authors.lastname: Unsal
authors.forename: E
authors.initials: E
authors.lastname: Yaris
authors.forename: C
authors.initials: C
authors.lastname: Ulku
authors.forename: N I
authors.initials: NI
authors.lastname: Kalyoncu
mesh_terms: D000014:Abnormalities, Drug-Induced; D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D001364:Awareness; D004363:Drug Utilization / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000453:epidemiology* / Q000209:etiology; D011256:Pregnancy Outcome; D049168:Pregnancy, Unplanned; D013723:Teratogens; D014421:Turkey / Q000453:epidemiology; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology
chemical_list: D000900:Anti-Bacterial Agents; D013723:Teratogens