Invasive colonic mucormycosis in early induction therapy of childhood acute lymphoblastic leukemia.
Fungal infections occur in patients who are severely immunocompromised with profound and prolonged neutropenia. We report a patient of acute lymphoblastic leukemia who developed nonspecific abdominal symptoms within two days after the onset of neutropenia in the early induction phase of chemotherapy, which was later found to be due to intestinal mucormycosis and resulted in a fatal outcome.
Sellappan
Boopathi
B
Departments of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Bakhshi
Sameer
S
Safaya
Rajni
R
Gupta
Arun K
AK
Arya
L S
LS
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D003108:Colonic Diseases / Q000175:diagnosis / Q000276:immunology* / Q000382:microbiology; D015897:Comorbidity; D004314:Down Syndrome / Q000453:epidemiology; D017809:Fatal Outcome; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D009091:Mucormycosis / Q000175:diagnosis / Q000276:immunology*; D009503:Neutropenia; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology