title: CO2 as a distending medium for gastric and small bowel MRI: a feasibility study.
abstract: This work evaluates carbon dioxide as a contrast medium for magnetic resonance imaging of the stomach and small bowel. Twelve healthy volunteers underwent rapid magnetic resonance imaging after oral administration of a carbon dioxide generating agent using a combination of breath-hold and interactive fluoroscopic imaging during breathing. Diagnostic-quality images were obtained in 100% of cases for the stomach and in 92, 75, 67 and 42% of cases for the duodenal segments 1-4, respectively. Visualisation of the jejunum and ileum proved unacceptable for clinical use and anti-peristaltic agents did not significantly influence the results. Further development of fast imaging and magnetic resonance interactive fluoroscopic methods may allow the use of carbon dioxide as a contrast medium for clinical imaging of the stomach and duodenum.
authors.affiliation: Department of Radiology, University of Cambridge and Addenbrooke's NHS Trust, Hills Road, Cambridge, CB2 2QQ, UK. djl15@radiol.cam.ac.uk
authors.forename: D J
authors.initials: DJ
authors.lastname: Lomas
authors.forename: S H
authors.initials: SH
authors.lastname: Habib
authors.forename: I J
authors.initials: IJ
authors.lastname: Joubert
authors.forename: E
authors.initials: E
authors.lastname: Sala
authors.forename: M J
authors.initials: MJ
authors.lastname: Graves
mesh_terms: D000328:Adult; D002245:Carbon Dioxide; D003287:Contrast Media; D004378:Duodenal Diseases / Q000000981:diagnostic imaging*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D013272:Stomach Diseases / Q000000981:diagnostic imaging*
chemical_list: D003287:Contrast Media; D002245:Carbon Dioxide