title: [Clinical study on the pharmacological treatment of hemorrhoids with 0.25% oxethacaine chlorhydrate].
abstract: In this clinical study, the authors refer to a thirty-six month treatment of Grades I and II haemorrhoids (pharmacological treatment) with a group of 75 patients (45 females and 30 males) and treatment for Grades III and IV haemorrhoids (Pharmacological and surgical treatment) on a second group of 23 patients for a total of 98 patients treated and observed. For the pharmacological treatment, a rectal cream containing 0.25% Oxethacaine chlorhydrate (Emoren, produced by Novasorel, srl) was used on all patients. The cream was applied intra-anally and on the external orifice twice a day, morning and evening, for ten days. In order to evaluate the therapeuctic effect, the following symptoms were monitored: pruritus, ematochezia, burning, tenesmus, and pain. The following results were demonstrated: a) in all patients: A reduction in pruritus, pain, blood and mucous loss, Elimination of tenesmus, Absence of peri-anal eczema, b) in 15 patients, haemorrhoids were reduced for 11 months. Therefore the results obtained reconfirm that local treatment with EMOREN demonstrated to be clinically efficient in the treatment of Grades I and II haemorrhoids as well as in post surgical treatment both for the attenuation and elimination of pain and the clinical objectives of the pathology in question.
authors.affiliation: Casa di Cura Villa delle Margherite, Torre del Greco (NA), Italia.
authors.forename: G
authors.initials: G
authors.lastname: Gioiella
authors.forename: S
authors.initials: S
authors.lastname: Crispo
authors.forename: P
authors.initials: P
authors.lastname: Mainiero
authors.forename: S
authors.initials: S
authors.lastname: Baktyari
authors.forename: S D
authors.initials: SD
authors.lastname: Ambrosio
authors.forename: A
authors.initials: A
authors.lastname: Canero
authors.forename: P
authors.initials: P
authors.lastname: Papagno
authors.forename: V
authors.initials: V
authors.lastname: Siano
authors.forename: A
authors.initials: A
authors.lastname: Mennella
authors.forename: G
authors.initials: G
authors.lastname: Vicedomini
authors.forename: V
authors.initials: V
authors.lastname: Pindozzi
authors.forename: M
authors.initials: M
authors.lastname: Gioiella
mesh_terms: D000328:Adult; D000368:Aged; D004983:Ethanolamines / Q000008:administration & dosage*; D005260:Female; D006484:Hemorrhoids / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D004983:Ethanolamines; C100289:oxethazaine