title: Silicone granuloma of the face treated with minocycline.
abstract: Siliconoma represents a granulomatous foreign body reaction to silicone, which is often used for soft tissue augmentation. Although considered as biologically inert for a long time, silicone has been implicated in various undesirable local and systemic reactions, sometimes with a latency period of up to several decades. Treatment of siliconomas is difficult and granulomas involving the face are a therapeutic challenge. We present a 43-year-old woman with a severely disfiguring facial silicone granuloma who was successfully treated with minocycline.
authors.affiliation: Department of Dermatology, University of Cologne, Cologne, Germany. meral.arin@medizin.uni-koeln.de
authors.forename: Meral J
authors.initials: MJ
authors.lastname: Arin
authors.forename: Jens
authors.initials: J
authors.lastname: Bäte
authors.forename: Thomas
authors.initials: T
authors.lastname: Krieg
authors.forename: Nicolas
authors.initials: N
authors.lastname: Hunzelmann
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D003357:Cosmetic Techniques / Q000009:adverse effects*; D005148:Facial Dermatoses / Q000188:drug therapy / Q000209:etiology; D005260:Female; D005548:Foreign-Body Migration; D015745:Granuloma, Foreign-Body / Q000188:drug therapy*; D006801:Humans; D007267:Injections; D008911:Minocycline / Q000627:therapeutic use*; D012828:Silicones / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D000893:Anti-Inflammatory Agents; D012828:Silicones; D008911:Minocycline