title: [Peculiarities in the effect of tofisopam and valerian extract on short-term memory and anxiety states in healthy humans].
abstract: Repeated administration of the anxiolytic tofisopam (grandaxin) reduced anxiety and improved both visual and verbal short-term memory in young male and female humans. The expression of these effects depends on the daytime (morning versus evening) and on the sex of volunteers. Valerian extract did not produce significant effect on the anxiety states and short-time memory.
authors.forename: é B
authors.initials: éB
authors.lastname: Arushanian
authors.forename: O A
authors.initials: OA
authors.lastname: Mastiagina
authors.forename: A P
authors.initials: AP
authors.lastname: Popova
mesh_terms: D000293:Adolescent; D000328:Adult; D000928:Antidepressive Agents / Q000008:administration & dosage*; D001007:Anxiety / Q000188:drug therapy*; D001569:Benzodiazepines / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D008570:Memory, Short-Term / Q000187:drug effects*; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage*; D012737:Sex Factors; D014632:Valerian
chemical_list: D000928:Antidepressive Agents; D010936:Plant Extracts; D001569:Benzodiazepines; C012582:tofisopam