Magnetoencephalographic localization of the basal temporal language area.
Magnetoencephalography (MEG) recordings were made on 25 native English-speaking patients with localization-related epilepsy during a semantic language task (verb generation). Eighteen right-handed subjects with normal reading ability had MEG scans performed during the same language task. MEG data was analyzed by MR-FOCUSS, a current density imaging technique. Detectable MEG signals arising from activation in the left fusiform gyrus, also known as the basal temporal language area (BTLA), occurred at 167 +/- 18 ms (n = 43) in all subjects. The BTLA has been associated with a variety of language production and comprehension tasks involving processing of semantic, orthographic, and phonologic information. MEG may become an important tool in efforts to further define the linguistic operations of specific regions within this language area.
Bowyer
Susan M
SM
Department of Neurology, Henry Ford Health System, Detroit, MI 48202, USA. drsusan@umich.edu
Fleming
Toya
T
Greenwald
Margaret L
ML
Moran
John E
JE
Mason
Karen M
KM
Weiland
Barbara J
BJ
Smith
Brien J
BJ
Barkley
Gregory L
GL
Tepley
Norman
N
D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D002648:Child; D004827:Epilepsy / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007802:Language; D015225:Magnetoencephalography; D008297:Male; D008875:Middle Aged; D013702:Temporal Lobe / Q000502:physiology*