Fluorescence enhancement of bis-acridine orange peptide, BAO, upon binding to double stranded DNA.
Bis-acridine orange peptides carrying two acridine oranges at the epsilon-amino moieties of both terminal lysines of a tetra(lysine) chain showed a ca. 200-fold fluorescence enhancement upon addition of double stranded DNA.
Mizuki
Keiji
K
Department of Applied Chemistry, Faculty of Engineering, Kyushu University, Fukuoka, 812-8581, Japan.
Sakakibara
Yutaka
Y
Ueyama
Hiroyuki
H
Nojima
Takahiko
T
Waki
Michinori
M
Takenaka
Shigeori
S
D000165:Acridine Orange / Q000031:analogs & derivatives* / Q000737:chemistry; D000818:Animals; D002417:Cattle; D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry; D015394:Molecular Structure; D009842:Oligopeptides / Q000138:chemical synthesis / Q000737:chemistry*; D011061:Poly A / Q000737:chemistry; D011067:Poly dA-dT / Q000737:chemistry; D011089:Polydeoxyribonucleotides / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet
D005456:Fluorescent Dyes; D009842:Oligopeptides; D011089:Polydeoxyribonucleotides; D011061:Poly A; C015465:poly(dA); D011067:Poly dA-dT; C019530:poly(dC-dG); D004247:DNA; C427203:calf thymus DNA; D000165:Acridine Orange