title: Long-term benefits of monteplase before coronary angioplasty in acute myocardial infarction.
abstract: Patients with acute myocardial infarction were randomly assigned to receive direct percutaneous coronary intervention (PCI) or pretreatment with intravenous monteplase followed by PCI. Although the combination of monteplase and PCI did not alter mortality compared with direct PCI, there was a dramatic reduction in the cardiac event rate over a 2-year follow-up compared with direct PCI.
authors.affiliation: Department of Cardiovascular & Renal Medicine, Saga University Faculty of Medicine, Saga, Japan. inouete@med.saga-u.ac.jp
authors.forename: Teruo
authors.initials: T
authors.lastname: Inoue
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Nishiki
authors.forename: Manabu
authors.initials: M
authors.lastname: Kageyama
authors.forename: Ryuji
authors.initials: R
authors.lastname: Chida
authors.forename: Terumi
authors.initials: T
authors.lastname: Hayashi
authors.forename: Kan
authors.initials: K
authors.lastname: Takayanagi
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Hikichi
authors.forename: Koichi
authors.initials: K
authors.lastname: Node
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D004638:Emergency Treatment; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000628:therapy*; D010960:Plasminogen Activators / Q000627:therapeutic use*; D011446:Prospective Studies; D055502:Secondary Prevention; D015912:Thrombolytic Therapy; D016896:Treatment Outcome
chemical_list: C468277:monteplase; D010960:Plasminogen Activators