title: [Resuscitation after prehospital cardiovascular arrest].
abstract: Initiation of effective cardiopulmonary resuscitation (CPR) at the earliest possible moment is the most important determinant of prognosis for prehospital cardiac arrest. The prognosis is essentially defined by two parameters: survival to hospital admission and survival to discharge. In connection with prehospital cardiac arrest, early defibrillation is particularly important, including the widespread availability of (semi)automatic defibrillators. Further aspects of CPR have recently received increased attention: on the one hand, changed study status regarding the use of antiarrhythmic agents (especially amiodarone), on the other hand, administration of vasopressin during resuscitation, and finally, the efficacy of mild hypothermia following prehospital cardiac arrest. These aspects represent the main subject of the present overview, which also addresses the latest revision of the International Liaison Committee on Resuscitation (ILCOR) guidelines on CPR that resulted in corresponding changes in the European Resuscitation Council (ERC) guidelines.
authors.affiliation: Medizinische Klinik III, Kardiologie, Johann Wolfgang Goethe-Universität. Klingenheben@bonn-kardiologie.de
authors.forename: T
authors.initials: T
authors.lastname: Klingenheben
authors.forename: A M
authors.initials: AM
authors.lastname: Zeiher
authors.forename: S
authors.initials: S
authors.lastname: Fichtlscherer
mesh_terms: D000638:Amiodarone / Q000008:administration & dosage; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage; D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D047548:Defibrillators; D004632:Emergency Medical Services / Q000379:methods*; D005060:Europe; D006323:Heart Arrest / Q000401:mortality / Q000628:therapy*; D017052:Hospital Mortality; D006801:Humans; D007036:Hypothermia, Induced; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D016019:Survival Analysis; D014667:Vasopressins / Q000008:administration & dosage
chemical_list: D000889:Anti-Arrhythmia Agents; D014667:Vasopressins; D000638:Amiodarone