[Review and analysis of present status of the micronization of Chinese traditional medicine].
Micronization is one of the methods to improve the solubility and bioavailability of drug, the micronization of TCM is a new techonology of TCM mordenization. status in quo of TCM micronization was reviewed and analyzed. Effects of micronization on the dissolution of active ingredients and pharmacological action were widely studied, however some fundmental aspects, such as engineering factors of superfine powder preparation, stability of them and the optimal particle size, are urgently to be studied.
Xu
Yue-hong
YH
Institute of Clinic Pharmacology, Guangzhou Traditional Chinese Medicine University, Guangzhou 510405, China.
Wang
Ning-sheng
NS
D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D010316:Particle Size; D010946:Plants, Medicinal / Q000737:chemistry; D011208:Powders; D012995:Solubility; D013678:Technology, Pharmaceutical / Q000379:methods*
D004365:Drugs, Chinese Herbal; D011208:Powders