Acute necrotizing ulcerative gingivitis and bacteremia caused by Stenotrophomonas maltophilia in an immunocompromised host.
An 8-year-old girl with leukemia developed acute necrotizing ulcerative gingivitis with Stenotrophomonas maltophilia and herpes simplex virus. Progression to bacteremia with pathologic evidence of osteomyelitis occurred despite appropriate antimicrobial therapy. This case highlights the importance of prompt recognition, debridement and appropriate therapy in immunocompromised patients with acute necrotizing ulcerative gingivitis.
Miyairi
Isao
I
Department of Infectious Diseases, St. Jude Children's Research Hospital, University of Tennessee Health Science Center, Memphis, TN 38105, USA. Isao.Miyairi@stjude.org
Franklin
Jeremy A
JA
Andreansky
Martin
M
Knapp
Katherine M
KM
Hayden
Randall T
RT
D016470:Bacteremia / Q000382:microbiology*; D002051:Burkitt Lymphoma / Q000150:complications*; D002648:Child; D005260:Female; D005892:Gingivitis, Necrotizing Ulcerative / Q000382:microbiology* / Q000821:virology*; D016905:Gram-Negative Bacterial Infections / Q000209:etiology*; D006561:Herpes Simplex / Q000209:etiology; D006801:Humans; D009894:Opportunistic Infections / Q000209:etiology; D020615:Stenotrophomonas maltophilia / Q000302:isolation & purification*