title: Synthesis of cimiracemate B, a phenylpropanoid found in Cimicifuga racemosa.
abstract: The synthesis of the rare bioactive phenylpropanoid ester known as cimiracemate B (1) from black cohosh, Cimicifuga racemosa, is described. The procedure employs a coupling method using 1, l'-carbonyldiimidazole and methyltrifluoromethanesulfonate as coupling reagents in the presence of N-methylmorpholine.
authors.affiliation: Program for Collaborative Research in the Pharmaceutical Sciences (PCRPS, M/C 877) and UIC/NIH Center for Botanical Dietary Supplements Research, College of Pharmacy, University of Illinois at Chicago, 833 S. Wood St. Chicago, IL 60612, USA.
authors.forename: Shao-Nong
authors.initials: SN
authors.lastname: Chen
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Fabricant
authors.forename: Guido F
authors.initials: GF
authors.lastname: Pauli
authors.forename: Harry H S
authors.initials: HH
authors.lastname: Fong
authors.forename: Norman R
authors.initials: NR
authors.lastname: Farnsworth
mesh_terms: D031885:Cimicifuga / Q000737:chemistry*; D010666:Phenylpropionates / Q000138:chemical synthesis*; D010946:Plants, Medicinal
chemical_list: D010666:Phenylpropionates; C499963:cimiracemate B