title: Autoimmune hepatitis in transplanted liver.
abstract: Liver transplantation is recognized as the appropriate treatment for end-stage liver disease. Four patients undergoing liver transplantation for classical end-stage liver disease developed de novo autoimmune hepatitis (AIH) in the graft. Recurrence of AIH after orthotopic liver transplantation and after reduction in immunosuppressive treatment is reported in one other patient. Markedly elevated serum transaminases were observed, together with an elevated serum IgG and/or globulin fraction and histological feature typical of AIH on liver biopsy.
authors.affiliation: Department of Gastroenterology, Hepatology, and Immunology, Children's Memorial Health Institute, Warsaw, Poland.
authors.forename: I
authors.initials: I
authors.lastname: Jankowska
authors.forename: J
authors.initials: J
authors.lastname: Pawlowska
authors.forename: M
authors.initials: M
authors.lastname: Teisseyre
authors.forename: P
authors.initials: P
authors.lastname: Kalicinski
authors.forename: A
authors.initials: A
authors.lastname: Kaminski
authors.forename: P
authors.initials: P
authors.lastname: Czubkowski
authors.forename: J
authors.initials: J
authors.lastname: Cielecka-Kuszyk
authors.forename: P
authors.initials: P
authors.lastname: Kluge
authors.forename: M
authors.initials: M
authors.lastname: Wozniak
authors.forename: U
authors.initials: U
authors.lastname: Oldakowska-Jedynak
authors.forename: J
authors.initials: J
authors.lastname: Socha
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D019693:Hepatitis, Autoimmune / Q000473:pathology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016031:Liver Transplantation / Q000276:immunology / Q000473:pathology*; D008297:Male; D012086:Reoperation
chemical_list: D007166:Immunosuppressive Agents