Growth hormone and GnRHa combination therapy in the management of precocious puberty.
Growth hormone when used in precocious puberty in combination with Gonadotropin releasing hormone analogue (GnRHa) instead of using GnRHa alone has been shown to improve final height prognosis. We report here a two-year follow-up of three cases of precocious puberty, two of whom were treated with a combination of GH and GnRHa and the third treated with GnRHa alone.
Khadilkar
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VV
Growth and Pediatric Endocrine Research Unit, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, 32, Sassoon Road, Pune 411 001, Maharashtra. akhadilkar@vsnl.net
Khadilkar
V V
VV
Maskati
G B
GB
D001827:Body Height; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000627:therapeutic use*; D013006:Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D011629:Puberty, Precocious / Q000188:drug therapy*
D007987:Gonadotropin-Releasing Hormone; D013006:Growth Hormone