[Influence of complex plant polyphenol preparation Eklikit on process of liver functions recovery after alcohol intoxication].
The comparative study was carried out to estimate hepatoprotective activity of the preparation "Eklikit", that represents the extract from the Shizandra chinensis crests and reference hepatoprpotector "Legalon" under acute alcohol intoxication. It was found that "Eklikit" posseses membrane protective and expressed hepatoprotective activity. "Eklikit" exceeds the reference hepatorpotector, "Legalon", in its ability to increase the oxidized form of NAD+ and reduced glutatione, cholesterol ethers and reduce the time of thiopental sleep. In other cases "Eklikit" was equally effective to "Legalon".
Kushnerova
N F
NF
Sprygin
V G
VG
Rakhmanin
Iu A
IuA
D000435:Alcoholic Intoxication / Q000188:drug therapy*; D000818:Animals; D005419:Flavonoids / Q000627:therapeutic use*; D008099:Liver / Q000503:physiopathology; D008297:Male; D010636:Phenols / Q000627:therapeutic use*; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D059808:Polyphenols; D051381:Rats; D017208:Rats, Wistar; D020127:Recovery of Function / Q000187:drug effects; D032141:Schisandra
D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts; D059808:Polyphenols