Prevalence of ulnar neuropathy in patients receiving hemodialysis.
BACKGROUND
Ulnar neuropathy can cause pain, weakness, and sensory changes in the hand and can result in functional impairment. Patients with end-stage renal disease receiving hemodialysis may be predisposed to ulnar neuropathy by factors such as arm positioning during hemodialysis, underlying polyneuropathy, and upper extremity vascular access.


OBJECTIVE
To determine the prevalence of clinically evident ulnar neuropathy in a cohort of 102 patients with end-stage renal disease receiving hemodialysis.


METHODS
All eligible patients in a single dialysis unit were screened for symptoms and signs of ulnar neuropathy. Those with at least 1 symptom or sign underwent nerve conduction studies to confirm the presence of ulnar neuropathy.


RESULTS
Clinically evident, electrophysiologically confirmed ulnar neuropathy was present in 37 (51%) of the 73 subjects with both screening and nerve conduction study data available. The true prevalence of ulnar neuropathy in this cohort was estimated between 41% and 60%.


CONCLUSIONS
There is a high prevalence of ulnar neuropathy in patients with end-stage renal disease receiving hemodialysis, which has not been previously recognized. The high prevalence of ulnar neuropathy in this population suggests that preventative efforts are indicated to prevent this functionally limiting complication.
Nardin
Rachel
R
Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA. rnardin@bidmc.harvard.edu
Chapman
Kristine M
KM
Raynor
Elizabeth M
EM
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction / Q000502:physiology; D015995:Prevalence; D006435:Renal Dialysis / Q000009:adverse effects* / Q000639:trends; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome; D020424:Ulnar Neuropathies / Q000453:epidemiology* / Q000209:etiology