Effect of humidified and heated CO2 during gynecologic laparoscopic surgery on analgesic requirements and postoperative pain.
OBJECTIVE
To determine the effect of humidified and heated CO(2) for pneumoperitoneum during laparoscopic surgery on analgesic requirements, postoperative pain, and patient satisfaction.


METHODS
Prospective, randomized, double-blind, controlled study (Canadian Task Force classification I).


METHODS
University hospital.


METHODS
Ninety consecutive women scheduled for gynecologic laparoscopic surgery.


METHODS
Operative laparoscopic management of adnexa surgery or adhesiolysis.


RESULTS
Thirty consecutive patients were randomized into each study group. Group I received humidified, heated gas; group II dry, heated gas; and group III (control group) standard dry, cold gas. No significant difference in intraoperative and postoperative analgesic requirements or postoperative pain score between group I and group II was found. There was even a tendency (not significant) toward less pain and higher postoperative satisfaction in patients in the control group. Therefore, the evaluation was stopped after 53 patients.


CONCLUSIONS
The use of humidified, heated gas did not reduce postoperative pain or intraoperative analgesic requirements and is thus not preferable to standard dry, cold gas in gynecologic laparoscopic surgery.
Kissler
Stefan
S
Division of Gynecologic Endocrinology and Reproductive Medicine, Department of Obstetrics and Gynecology, Johann Wolfgang Goethe-University, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany.
Haas
Marianne
M
Strohmeier
Renate
R
Schmitt
Hubert
H
Rody
Achim
A
Kaufmann
Manfred
M
Siebzehnruebl
Ernst
E
D000290:Adnexa Uteri / Q000601:surgery; D000328:Adult; D002245:Carbon Dioxide / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006358:Hot Temperature / Q000627:therapeutic use*; D006801:Humans; D006813:Humidity; D007263:Infusions, Parenteral; D010535:Laparoscopy / Q000379:methods*; D010149:Postoperative Pain / Q000188:drug therapy* / Q000517:prevention & control*; D011027:Pneumoperitoneum; D011028:Pneumoperitoneum, Artificial / Q000379:methods; D011446:Prospective Studies; D016896:Treatment Outcome
D002245:Carbon Dioxide