title: [Infantile spasms and West syndrome].
abstract: West syndrome, an epileptic encephalopathy of infancy and early childhood with variable etiology, consist of the triad of infantile spasms, arrest or regress of psychomotor development and specific EEG pattern of hypsarrhythmia. Infantile spasms occur within the first year of life. West syndrome has proved to be resistant to treatment, although VPA and benzodiazepines have been shown to be helpful. Then is general agreement that ACTH or oral corticosteroids remain the treatment of choice, especially in idiopathic cases, which have a better prognosis.
authors.affiliation: Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină, 1 Clinica a III-a Pediatrie.
authors.forename: Georgeta
authors.initials: G
authors.lastname: Diaconu
authors.forename: Ioana
authors.initials: I
authors.lastname: Grigore
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use; D001569:Benzodiazepines / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D006801:Humans; D007223:Infant; D013036:Spasms, Infantile / Q000175:diagnosis / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D001569:Benzodiazepines; D000324:Adrenocorticotropic Hormone