Cyclosporin A therapy in a case with hyperimmunoglobulin E and nephrotic syndrome.
We describe the beneficial effects of treatment with cyclosporin A in a 10-year-old boy with hyperimmunoglobulin E and refractory nephrotic syndrome. The patient was initially resistant to steroid therapy with prednisolone alone. Additional therapy with cyclosporin A was then prescribed, effectively reducing levels of serum immunoglobulin E and preventing flare up of nephrotic syndrome.
Bong
Chin-Nam
CN
Department of Pediatrics, Pingtung Christian Hospital, Pingtung, Taiwan.
Huang
Shun-Chen
SC
Wang
Chih-Lu
CL
Liu
Po-Mai
PM
Chen
Hsin-Hsu
HH
Yang
Kuender D
KD
D002648:Child; D016572:Cyclosporine / Q000627:therapeutic use*; D006801:Humans; D007589:Job Syndrome / Q000188:drug therapy*; D008297:Male; D009404:Nephrotic Syndrome / Q000188:drug therapy*; D011241:Prednisone / Q000627:therapeutic use; D018417:Th1 Cells / Q000276:immunology; D018418:Th2 Cells / Q000276:immunology
D016572:Cyclosporine; D011241:Prednisone