[Calcification of the falx cerebri. A pathognomonic symptom of Gorlin-Goltz syndrome].
BACKGROUND
Gorlin-Goltz syndrome is an autosomal dominant disorder with variable penetration characterized primarily by keratocysts of the jaws, multiple basal cell carcinomas, skeletal abnormalities and intracranial calcifications.


METHODS
In this study, 4787 radiographs with occipitomental x-rays from the hospital archives for oral and maxillofacial surgery of the Christian Albrechts University Kiel were examined for calcifications in the area of the falx cerebri.


RESULTS
Four characteristic alterations in the falx cerebri could be assigned to four groups of structures. Those in group 4 could be found only within Gorlin-Goltz syndrome patients, and differed significantly in form and extent from the remaining three groups.


CONCLUSIONS
The plurilamellar appearance of this group could be rated as a pathognomonic symptom of the Gorlin-Goltz syndrome.
Lambrecht
J T
JT
Klinik für Zahnärztliche Chirurgie, - Radiologie, Mund- und Kieferheilkunde, Universität Basel. J-Thomas.Lambrecht@unibas.ch
Stübinger
S
S
Siewert
B
B
Härle
F
F
D000293:Adolescent; D000328:Adult; D000368:Aged; D001478:Basal Cell Nevus Syndrome / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D001927:Brain Diseases / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D002648:Child; D015897:Comorbidity; D004388:Dura Mater / Q000000981:diagnostic imaging*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors