title: Preliminary investigation of respiratory self-gating for free-breathing segmented cine MRI.
abstract: Segmented cine MRI generally requires breath-holding, which can be problematic for many patients. Navigator echo techniques, particularly successful for free-breathing coronary MRA, are incompatible with the acquisition strategies and SSFP pulse sequences commonly used for cine MRI. The purpose of this work is to introduce a new self-gating technique deriving respiratory gating information directly from the raw imaging data acquired for segmented cine MRI. The respiratory self-gating technique uses interleaved radial k-space sampling to provide low-resolution images in real time during the free-breathing acquisition that are compared to target expiration images. Only the raw data-producing images with high correlation to the target images are included in the final high-resolution reconstruction. The self-gating technique produced cine series with no significant differences in quantitative image sharpness to series produced using comparable breath-held techniques. Because of the difficulties associated with breath-holding, the respiratory self-gating technique represents an important practical advance for cardiac MRI. , Inc.
authors.affiliation: Department of Biomedical Engineering, NorthWestern University, Chicago, IL 60611, USA. alarson@radiology.northwestern.edu
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Larson
authors.forename: Peter
authors.initials: P
authors.lastname: Kellman
authors.forename: Andrew
authors.initials: A
authors.lastname: Arai
authors.forename: Glenn A
authors.initials: GA
authors.lastname: Hirsch
authors.forename: Elliot
authors.initials: E
authors.lastname: McVeigh
authors.forename: Debiao
authors.initials: D
authors.lastname: Li
authors.forename: Orlando P
authors.initials: OP
authors.lastname: Simonetti
mesh_terms: D000465:Algorithms; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods; D008297:Male; D012119:Respiration