title: Clinical status of at-risk individuals 5 years later: further validation of the psychometric high-risk strategy.
abstract: The authors hypothesized that at-risk individuals identified on the basis of their Chapman scale scores would be diagnosed with schizophrenia-spectrum disorders at follow-up. In the present study, the authors interviewed 135 young adults approximately 5 years following their initial assessment. The at-risk groups included high scorers on the Perceptual Aberration and/or Magical Ideation Scales (n=59) and high scorers on the revised Social Anhedonia Scale (n=32). The control participants (n=44) scored below 0.5 SD of the same-sex group means on all the scales. At the follow-up, the groups differed in terms of their likelihood of having a schizophrenia-spectrum diagnosis, Chi2(2)=9.79, p<.01. The at-risk groups reported more frequent and severe psychotic-like experiences relative to the control group. These findings support the predictive validity of the Chapman psychosis-proneness scales and may enhance the power of early detection efforts.
authors.affiliation: Department of Psychology and Psychiatry, University of Wisconsin-Madison, Madison, WI 53706, USA. dgooding@facstaff.wisc.edu
authors.forename: Diane C
authors.initials: DC
authors.lastname: Gooding
authors.forename: Kathleen A
authors.initials: KA
authors.lastname: Tallent
authors.forename: Christie W
authors.initials: CW
authors.lastname: Matts
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011594:Psychometrics / Q000379:methods*; D015203:Reproducibility of Results; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis / Q000453:epidemiology*; D012565:Schizophrenic Psychology; D012720:Severity of Illness Index; D012919:Social Behavior; D011795:Surveys and Questionnaires; D013850:Thinking; D013997:Time Factors