title: Pathogenesis of pulmonary arterial hypertension: the need for multiple hits.
authors.forename: Jason X-J
authors.initials: JX
authors.lastname: Yuan
authors.forename: Lewis J
authors.initials: LJ
authors.lastname: Rubin
mesh_terms: D052006:Bone Morphogenetic Protein Receptors, Type II; D020022:Genetic Predisposition to Disease; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology / Q000235:genetics*; D018895:Microsatellite Repeats; D009154:Mutation; D011110:Polymorphism, Genetic; D017346:Protein Serine-Threonine Kinases / Q000235:genetics*; D011651:Pulmonary Artery / Q000166:cytology / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D017346:Protein Serine-Threonine Kinases; C498218:BMPR2 protein, human; D052006:Bone Morphogenetic Protein Receptors, Type II