title: Chemistry of isocoumarins: synthesis and biological screenings of homalicine and dihydrohomalicine.
abstract: Total synthesis and selected biological activities of naturally occurring homalicine and (dl)-dihydrohomalicine are described.
authors.affiliation: Department of Chemistry, Quaid-i-Azam University, Islamabad-45320 Pakistan.
authors.forename: Muhammad T
authors.initials: MT
authors.lastname: Hussain
authors.forename: Nasim H
authors.initials: NH
authors.lastname: Rama
authors.forename: Shahid
authors.initials: S
authors.lastname: Hameed
authors.forename: A
authors.initials: A
authors.lastname: Malik
authors.forename: Khalid M
authors.initials: KM
authors.lastname: Khan
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D001156:Artemia / Q000187:drug effects; D003374:Coumarins / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006801:Humans; D007928:Lethal Dose 50; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D031308:Salicaceae
chemical_list: D000890:Anti-Infective Agents; D003374:Coumarins; D010936:Plant Extracts; C500033:homalicine