Endoscopic resection for the diagnosis of visceral Kaposi's sarcoma.
Kaposi's sarcoma is an uncommon neoplasm that occasionally involves the gastrointestinal tract in immunosuppressed individuals. Infection with human herpes virus 8 is known to be necessary for developing all forms of Kaposi's sarcoma. We report a renal transplant recipient who developed visceral Kaposi's sarcoma 18 months after the transplantation. In Oriental countries, the incidence of Kaposi's sarcoma is extremely low, and this is the first case of Kaposi's sarcoma arising from a transplant recipient in Japan. Standard forceps biopsies of the gastric lesions failed to make the correct diagnosis. However, endoscopic resection successfully led to the correct diagnosis of Kaposi's sarcoma and herpes simplex virus 8 infection as well. This is the first report of a patient with visceral Kaposi's sarcoma who underwent endoscopic resection that reliably confirmed histological diagnosis and the viral genome at the same time.
Sakagami
Junichi
J
Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajiicho Hirokoji Kamigyoku, Kyoto 602-8566, Japan.
Sogame
Yoshio
Y
Kataoka
Keisho
K
Kanemitsu
Daisuke
D
Takada
Ryusuke
R
Ito
Reiko
R
Motoyoshi
Tomoko
T
Mitsufuji
Shoji
S
Okanoue
Takeshi
T
Akioka
Kiyokazu
K
Okamoto
Masahiko
M
Yoshimura
Norio
N
D016145:Endoscopy, Digestive System; D019160:Endosonography; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis* / Q000601:surgery / Q000821:virology; D019288:Herpesvirus 8, Human; D006801:Humans; D008297:Male; D008875:Middle Aged; D012514:Sarcoma, Kaposi / Q000175:diagnosis* / Q000601:surgery / Q000821:virology