title: Naravelia zeylanica [corrected] occurrence of primary benzamides in flowering plants.
abstract: Extract of Naravelia zeylanica (Ranunculaceae) yielded three simple benzamides, 3,4-methylenedioxybenzamide, 4-methoxybenzamide and 4-hydroxy-3-methoxybenzamide. These simple C6C1 metabolites have been encountered as natural products for the first time. The compounds were identified by direct comparison of their spectral (1H- and 13C-NMR) and chromatographic (GCMS) data with those of authentic samples. Authentic 4-hydroxy-3-methoxybenzamide was synthesized in one step by treatment of 4-hydroxy-3-methoxybenzonitrile with sodium perborate. Authentic 3,4-methylenedioxybenzamide was synthesized from the corresponding acid.
authors.affiliation: Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, Universitetsparken 2, DK-2100 Copenhagen, Denmark. jj@dfuni.dk
authors.forename: Jerzy W
authors.initials: JW
authors.lastname: Jaroszewski
authors.forename: Dan
authors.initials: D
authors.lastname: Staerk
authors.forename: Sören Boe
authors.initials: SB
authors.lastname: Holm-Móller
authors.forename: Thomas Hógh
authors.initials: TH
authors.lastname: Jensen
authors.forename: Henrik
authors.initials: H
authors.lastname: Franzyk
authors.forename: Brinda
authors.initials: B
authors.lastname: Somanadhan
mesh_terms: D001549:Benzamides / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification*; D035264:Flowers / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000032:analysis; D029626:Ranunculaceae / Q000737:chemistry*
chemical_list: D001549:Benzamides; D010936:Plant Extracts