Efficient syntheses of 5-aminoalkyl-1h-tetrazoles and of polyamines incorporating tetrazole rings.
Linear N(omega)-tritylated omega-amino thiobenzylamides and N(alpha),N(omega)-ditritylated polyamino mono- or bisthioamides were efficiently converted to the corresponding tetrazole derivatives upon treatment with azidotrimethylsilane under Mitsunobu reaction conditions. [reaction: see text]
Athanassopoulos
Constantinos M
CM
Department of Chemistry, University of Patras, GR-265 00 Patras, Greece. kath@chemistry.upatras.gr
Garnelis
Thomas
T
Vahliotis
Dimitrios
D
Papaioannou
Dionissios
D
D000577:Amides / Q000737:chemistry*; D007202:Indicators and Reagents; D008958:Models, Molecular; D011073:Polyamines / Q000138:chemical synthesis*; D013777:Tetrazoles / Q000138:chemical synthesis*
D000577:Amides; D007202:Indicators and Reagents; D011073:Polyamines; D013777:Tetrazoles