title: Pattern of birth in early-onset anorexia nervosa: an equatorial study.
abstract: OBJECTIVE
  Patients with anorexia nervosa (AN) born in the northern and southern hemispheres are more likely to be born during spring months than at any other time of the year. It has been hypothesized that environmental temperature at the time of conception may have a significant role in this pattern of findings. The current study aims to investigate the pattern of birth of early-onset AN patients in an equatorial region (Singapore), where there is little difference in environmental temperature throughout the year.
  
  
  METHODS
  Dates of birth were collected for 102 patients who were born in Singapore and diagnosed with early-onset AN. The patterns of birth were analyzed using chi-square analysis.
  
  
  RESULTS
  There was no difference across the year in the birth patterns of patients with early-onset AN in Singapore, nor were there any differences between patients with restrictive and binge/purge AN.
  
  
  CONCLUSIONS
  This lack of seasonal variation in the equator adds support to the "temperature at conception" hypothesis.
authors.affiliation: Department of Mental Health, St. George's Hospital Medical School, University of London, London, United Kingdom. k.willoughby@sghms.ac.uk
authors.forename: Kate
authors.initials: K
authors.lastname: Willoughby
authors.forename: Rebecca
authors.initials: R
authors.lastname: Bowen
authors.forename: Ee-Lian
authors.initials: EL
authors.lastname: Lee
authors.forename: Parvathy
authors.initials: P
authors.lastname: Pathy
authors.forename: Bryan
authors.initials: B
authors.lastname: Lask
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D000856:Anorexia Nervosa / Q000453:epidemiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D036801:Parturition; D012189:Retrospective Studies; D012307:Risk Factors; D012621:Seasons; D012846:Singapore / Q000453:epidemiology