[Biological resonance as a possible mechanism of an ototoxic action of aminoglycoside antibiotics].
Literature data on mechanisms of an ototoxic action of aminoglycoside antibiotics (AGA) doubt pharmacological basis of this phenomenon. It is suggested that the above ototoxicity may result from wave interference between wave processes in the inner ear and electromagnetic AGA field. The interaction is primary, informative and initiate apoptosis of the hair cells of the internal ear. The model experiment showed feasibility of frequency-resonance interaction between AGA and biopreparations of the acoustic apparatus of the animals.
Abakarov
M G
MG
Belousov
Iu B
IuB
Gotovskiĭ
Iu V
IuV
D000617:Aminoglycosides / Q000633:toxicity*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000633:toxicity*; D002417:Cattle; D004432:Ear, Middle / Q000187:drug effects / Q000503:physiopathology*; D004574:Electromagnetic Fields; D008954:Models, Biological; D009924:Organ Culture Techniques; D013552:Swine
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents