title: Tenosynovitis of the wrist due to resistant Mycobacterium tuberculosis in a heart transplant patient.
abstract: Tubercular tenosynovitis is now rare, which can delay diagnosis of this disease. We report a case of tenosynovitis of the wrist in a heart transplant patient caused by an isoniazid- and streptomycin-resistant Mycobacterium tuberculosis strain. Despite immunosuppression therapy, which can lead to a smoldering evolution, molecular biology analysis of biopsies allowed a rapid diagnosis.
authors.affiliation: Microbiology Laboratory UPRES-EA 1254, University Hospital, Rennes, France. alexandre.le-meur@chu-rennes.fr
authors.forename: Alexandre
authors.initials: A
authors.lastname: Le Meur
authors.forename: Cédric
authors.initials: C
authors.lastname: Arvieux
authors.forename: Pascal
authors.initials: P
authors.lastname: Guggenbuhl
authors.forename: Michel
authors.initials: M
authors.lastname: Cormier
authors.forename: Anne
authors.initials: A
authors.lastname: Jolivet-Gougeon
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000995:Antitubercular Agents / Q000494:pharmacology; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D007538:Isoniazid / Q000494:pharmacology; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000302:isolation & purification*; D013307:Streptomycin / Q000494:pharmacology; D013717:Tenosynovitis / Q000175:diagnosis* / Q000382:microbiology*; D018088:Tuberculosis, Multidrug-Resistant / Q000175:diagnosis* / Q000382:microbiology; D014953:Wrist / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D000995:Antitubercular Agents; D007538:Isoniazid; D013307:Streptomycin