[Neuropsychological evaluation of long-term therapy of Alzheimer's disease using different cerebrolysin dosages].
An open comparative randomized clinico-neuropsychological study of 4 cerebrolysin treatment courses was conducted during 19 months. The differences in long-term effects of different medication dosages (10 and 30 ml) were revealed. The higher cerebrolysin dose was more effictive for cognitive functioning of patients. In patients receiving a dosage of 10 ml, the disease progress was significantly more pronounced. The results obtained indicate that a course of cerebrolysin treatment in higher dosages significantly inhibited neurodegenerative process.
Roshchina
I F
IF
Gavrilova
S I
SI
Zharikov
G A
GA
Kalyn
Ia B
IaB
Kolykhalov
I V
IV
Selezneva
N D
ND
D000544:Alzheimer Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D000596:Amino Acids / Q000008:administration & dosage / Q000627:therapeutic use*; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D018697:Nootropic Agents / Q000008:administration & dosage / Q000627:therapeutic use*
D000596:Amino Acids; D018697:Nootropic Agents; C006952:cerebrolysin