Localized reversible reduction of apparent diffusion coefficient in transient hypoglycemia-induced hemiparesis.
OBJECTIVE
The pathophysiology of hypoglycemia shares a common mechanism with cerebral ischemia, but so far, little is known regarding MRI of humans with hypoglycemia.


METHODS
We report a patient with left hemiparesis and dysarthria associated with a blood glucose level of 1.7 mmol/L. The patient recovered completely after glucose infusion.


RESULTS
The initial diffusion-weighted imaging (DWI) showed increased signal intensities and a reduction of apparent diffusion coefficient (ADC) values localized in the corpus callosum (splenium) and asymmetrically in the corona radiata. After 48 hours, follow-up revealed complete recovery of DWI and ADC signal abnormalities.


CONCLUSIONS
To our knowledge, this is the first presentation of a case with transient hypoglycemia-induced focal neurological deficits revealing completely reversible MRI changes in terms of disturbed DWI and ADC with a peculiar as yet undescribed topography.
Böttcher
J
J
Department of Diagnostic and Interventional Radiology, Friedrich-Schiller-University Jena, Erlanger Allee 101, 07747 Jena, Germany. joachim.boettcher@med.uni-jena.de
Kunze
A
A
Kurrat
C
C
Schmidt
P
P
Hagemann
G
G
Witte
O W
OW
Kaiser
W A
WA
D000368:Aged; D001786:Blood Glucose / Q000378:metabolism / Q000502:physiology; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D004401:Dysarthria / Q000097:blood / Q000209:etiology; D006801:Humans; D007003:Hypoglycemia / Q000150:complications*; D008297:Male; D010291:Paresis / Q000097:blood* / Q000209:etiology*
D001786:Blood Glucose