title: Chronic recurrent multifocal osteomyelitis: two cases of sacral disease responsive to corticosteroids.
abstract: Chronic recurrent multifocal osteomyelitis is a rare inflammatory form of osteomyelitis of unknown etiology. It affects children and adolescents, and signs and symptoms include recurrent episodes of bone pain, tenderness, possible constitutional upset, and increased inflammatory markers. We present 2 patients with cases of chronic recurrent multifocal osteomyelitis affecting the sacrum who responded dramatically to treatment with corticosteroids.
authors.affiliation: Department of Rheumatology, Nuffield Orthopaedic Centre, Oxford, United Kingdom. wendy.holden@noc.anglox.nhs.uk
authors.forename: Wendy
authors.initials: W
authors.lastname: Holden
authors.forename: Joel
authors.initials: J
authors.lastname: David
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D002648:Child; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D010019:Osteomyelitis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011239:Prednisolone / Q000627:therapeutic use; D011859:Radiography; D012008:Recurrence; D012447:Sacrum / Q000000981:diagnostic imaging*; D013122:Spinal Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D011239:Prednisolone; D008775:Methylprednisolone