[Karyotypic investigation of two cases of invasive candidiasis].
Investigation of the genetic relationship of the three Candida albicans strains isolated from each of two patients, one with C. albicans meningitis and the other with pancreatic pseudocyst (PP), by PFGE (pulsed-field gel electrophoresis), was aimed in this study. Three strains of C. albicans isolated from bloodstream, abscess and drainage fluid of the patient with PP were found to show the same karyotype, while three strains of C. albicans from cerebrospinal fluid, nasopharyngeal swab culture and stool sample of the patient with meningitis were found closely related. As a conclusion, PFGE enables to give valuable information about the probable source of transmission on individual basis in these two invasive candida infections.
Saraçli
Mehmet A
MA
Gülhane Askeri Tip Akademisi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dali, Ankara.
Yildiran
S Taner
ST
Yağci
Gökhan
G
Ozdağ
Fatih
F
Doğanci
Levent
L
D000038:Abscess / Q000382:microbiology; D000328:Adult; D002176:Candida albicans / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D002177:Candidiasis / Q000382:microbiology* / Q000635:transmission; D002555:Cerebrospinal Fluid / Q000382:microbiology; D016521:Electrophoresis, Gel, Pulsed-Field; D005243:Feces / Q000382:microbiology; D016469:Fungemia / Q000382:microbiology; D006801:Humans; D007621:Karyotyping / Q000379:methods*; D008297:Male; D016921:Meningitis, Fungal / Q000382:microbiology*; D009305:Nasopharynx / Q000382:microbiology; D010192:Pancreatic Pseudocyst / Q000382:microbiology*