title: [Early diagnosis in hypertrophic cardiomyopathy--case report].
abstract: Disproportionate heart muscle enlargement compared with little or no chamber enlargement are characteristic for hypertrophic cardiomyopathy (HCM). The clinical course of HCM is highly variable. Many patients are asymptomatic or mildly symptomatic and may be relatives of patients with known disease. Unfortunately, the first clinical manifestation of the disease may be sudden death, frequently occurring in children and young adults, often during or after physical exertion. We present 2 cases of HCM who emphasize the variability of clinical and ECG modifications and underline the importance of routine echocardiography in patients with atypical cardiac symptoms in order to identify the disease and prevent high risk for sudden death.
authors.affiliation: Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină, Clinica a IV-a Medicală-Nefrologie.
authors.forename: Ioana Dana
authors.initials: ID
authors.lastname: Alexa
authors.forename: Laurette Graziella
authors.initials: LG
authors.lastname: Cozma
authors.forename: Gina
authors.initials: G
authors.lastname: Constantinescu
authors.forename: Larisa
authors.initials: L
authors.lastname: Panaghiu
authors.forename: Oana
authors.initials: O
authors.lastname: Paraschiv
authors.forename: Florentina
authors.initials: F
authors.lastname: Palade
mesh_terms: D000368:Aged; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D016757:Death, Sudden, Cardiac / Q000517:prevention & control; D042241:Early Diagnosis; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008875:Middle Aged