[Dynamics of calcium intake in the brain tissue in hypercholesterolemia].
A dynamics of calcium content in rat brain during endogenic hypercholesterolemia, caused by action of the stressful factor (restriction of vital space (80-100 sm2 per one individual) and high salt diet (2 g/kg)) was studied. It was revealed that under the given conditions there is an increase in calcium content in the brain. Nifedipine (2 mg/ kg per day) significantly reduced calcium content in the brain that has allowed making an assumption of some mechanisms of this phenomenon.
Miroshnichenko
A O
AO
Liashenko
V P
VP
Lukashov
S M
SM
D000818:Animals; D001921:Brain / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism*; D002784:Cholesterol / Q000097:blood; D004195:Disease Models, Animal; D006937:Hypercholesterolemia / Q000209:etiology / Q000378:metabolism*; D009543:Nifedipine / Q000494:pharmacology; D051381:Rats; D013315:Stress, Psychological / Q000150:complications
D002784:Cholesterol; D009543:Nifedipine; D002118:Calcium