title: Bowen's disease of the nipple-a new method of treatment.
abstract: Squamous cell carcinoma in situ (Bowen's disease) is a common skin condition but has only rarely been described on the nipple. All reported cases have been treated with wide local excision and observation. A new treatment for Bowen's disease is photodynamic therapy. This has been reported as being able to treat Bowen's disease in other sites effectively with an acceptable local recurrence rate. We describe two patients presenting with itching and scaling of the nipple which were histologically proven Bowen's disease, one of these patients was treated successfully with a combination of photodynamic therapy and cryotherapy: this is the first time such a lesion has been treated in this way.
authors.affiliation: Department of General Surgery, Princess Royal Hospital NHS Trust, Telford, Shropshire, UK. ptbrookes@doctors.org.uk
authors.forename: P T
authors.initials: PT
authors.lastname: Brookes
authors.forename: S
authors.initials: S
authors.lastname: Jhawar
authors.forename: C P
authors.initials: CP
authors.lastname: Hinton
authors.forename: S
authors.initials: S
authors.lastname: Murdoch
authors.forename: T
authors.initials: T
authors.lastname: Usman
mesh_terms: D000368:Aged; D001913:Bowen's Disease / Q000188:drug therapy*; D001943:Breast Neoplasms / Q000188:drug therapy*; D003131:Combined Modality Therapy; D017679:Cryotherapy; D005260:Female; D006801:Humans; D009558:Nipples / Q000473:pathology; D010778:Photochemotherapy; D012878:Skin Neoplasms / Q000188:drug therapy*