Investigations using clinically relevant particles. Reference: Im et al., The effect of COX-2 inhibitors on periprosthetic osteolysis, Biomaterials 25, 269-275 (2004).
Shanbhag
Arun
A
D000818:Animals; D001842:Bone and Bones / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D051546:Cyclooxygenase 2; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors / Q000008:administration & dosage*; D010014:Osteolysis / Q000188:drug therapy* / Q000209:etiology*; D010316:Particle Size; D011095:Polyethylenes / Q000009:adverse effects* / Q000737:chemistry; D011451:Prostaglandin-Endoperoxide Synthases / Q000276:immunology / Q000378:metabolism; D019736:Prostheses and Implants / Q000009:adverse effects*; D011475:Prosthesis Failure; D011817:Rabbits; D014945:Wound Healing / Q000187:drug effects
D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D011095:Polyethylenes; C111601:ultra-high molecular weight polyethylene; D051546:Cyclooxygenase 2; D011451:Prostaglandin-Endoperoxide Synthases