[Treating metastatic vertebral tumor with percutaneous vertebroplasty: a report of 28 cases].
OBJECTIVE
Treating metastatic vertebral tumor is a common difficulty. Conservative treatment can't efficiently release the pain, and establish the spinal column; while operation may destroy normal tissue, and cause many complications, which would prolong the time of in-hospital, and delay the treatment of primary disease, at the same time, operation is not suitable for multiple metastatic spinal tumors. This study was designed to investigate the efficacy of percutaneous vertebroplasty (PVP) on metastatic spinal tumor under the guidance of digital subtraction angiography (DSA).


METHODS
A total of 58 patients with metastatic spinal tumor were divided into 2 groups according to their intention, 28 (group A) were treated with PVP combined radiochemotherapy, 30 (group B) were treated with routine radiochemotherapy. Baselines of the 2 groups have no significant difference. Two months after treatment, the life quality, therapeutic response, stabilization of the vertebral column, and toxic effect were compared between group A and group B.


RESULTS
After treatment, both groups showed significant changes in life quality, and therapeutic response (P < 0.05, t(1)=2.74, t(2)=11.74). Group A showed no complication. Group B showed 5 cases of pathologic constrictive fracture in spinal body.


CONCLUSIONS
PVP is a simple and minimally invasive treatment with few complications, which can release pain, decrease incidence of pathologic constrictive fracture in spinal body, and improve life quality of patients with metastatic spinal tumor.
Yang
Zuo-Zhang
ZZ
Department of Orthopaedics, The Third Affiliated Hospital/Yunnan Provincial Tumor Hospital, Kunming Medical College, Kunming, Yunnan, 650118, P. R. China. yangzuozhang@yahoo.com.cn
Xu
Jian-Bo
JB
Yuan
Tao
T
Qian
Bao-Sheng
BS
Zhang
Jin-Yu
JY
Li
Wen-Zhong
WZ
Li
Jian-Lin
JL
Xiao
Yan-Bin
YB
Peng
Min
M
Li
Yu
Y
Luan
Li
L
D000368:Aged; D001416:Back Pain / Q000209:etiology / Q000628:therapy; D001843:Bone Cements / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000473:pathology; D003110:Colonic Neoplasms / Q000473:pathology; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures / Q000379:methods*; D010147:Pain Measurement; D011788:Quality of Life; D013125:Spinal Neoplasms / Q000556:secondary* / Q000601:surgery* / Q000628:therapy; D013904:Thoracic Vertebrae / Q000601:surgery*; D016896:Treatment Outcome
D001843:Bone Cements