Cervico-medullary desmoplastic infantile ganglioglioma: an unusual case with diffuse leptomeningeal dissemination at diagnosis.
Desmoplastic infantile ganglioglioma (DIG) is a rare intracranial tumor affecting newborns and infants, and generally arising in the supratentorial region. We report a case of an unusual DIG, arising at the cervico-medullary junction, with diffuse leptomeningeal seeding at diagnosis that was treated with chemotherapy (CT) and delayed partial surgery. The case we describe demonstrates that DIG can occur in the subtentorial region and can show leptomeningeal dissemination like other low-grade gliomas.
Milanaccio
Claudia
C
Dipartimento di Emato-Oncologia, Istituto Giannina Gaslini, Genova, Italia.
Nozza
Paolo
P
Ravegnani
Marcello
M
Rossi
Andrea
A
Raso
Alessandro
A
Gambini
Claudio
C
Garrè
Maria Luisa
ML
Pietsch
Torsten
T
D018303:Ganglioglioma / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000628:therapy; D011859:Radiography