title: Permanent vision loss in one eye following administration of local anesthesia for a dental extraction.
abstract: Prilocaine Plain, an amide local anesthetic (LA), is somewhat less potent than lidocaine and considerably less toxic after injection into peripheral tissues. Clinically, it produces less vasodilation and is similar to other amide LA in relative freedom from allergic reactions. It is reliably used in a plain solution for cardiac patients receiving short procedures. In this report a patient with a known diagnosis of bacterial endocarditis suffered permanent visual loss in the left eye immediately following dental extraction surgery prior to mitral valve surgery. The clinical implications indicate that the delivery of LA must be done with aspiration before and during the injection. This will possibly prevent intravascular injection, which can lead to fluid emboli occluding the ophthalmic artery with the devastating result of vision loss.
authors.affiliation: Vancouver General Hospital, 855 W. 12th Ave., Vancouver, BC, Canada V5Z-Im9.
authors.forename: B
authors.initials: B
authors.lastname: Rishiraj
authors.forename: J B
authors.initials: JB
authors.lastname: Epstein
authors.forename: D
authors.initials: D
authors.lastname: Fine
authors.forename: S
authors.initials: S
authors.lastname: Nabi
authors.forename: N K
authors.initials: NK
authors.lastname: Wade
mesh_terms: D000368:Aged; D000766:Anesthesia, Dental / Q000009:adverse effects*; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000009:adverse effects*; D001766:Blindness / Q000209:etiology*; D004617:Embolism / Q000209:etiology; D004697:Endocarditis, Bacterial / Q000175:diagnosis; D006801:Humans; D007267:Injections / Q000009:adverse effects; D008297:Male; D008437:Maxilla; D009880:Ophthalmic Artery / Q000473:pathology; D011318:Prilocaine / Q000008:administration & dosage / Q000009:adverse effects*; D014081:Tooth Extraction / Q000009:adverse effects; D015349:Vision, Monocular; D014792:Visual Acuity
chemical_list: D000779:Anesthetics, Local; D011318:Prilocaine