[Effect of 32P irradiation on cell cycle of HL-60 cells].
OBJECTIVE
To investigate the effect of (32)P irradiation on the cell cycle of HL-60 cells.


METHODS
Flow cytometry was employed to detect cell cycle changes of HL-60 cells induced by (32)P irradiation at different doses for varied time lengths (24, 28 and 72 h, respectively).


RESULTS
(32)P could induce cell cycle arrest in S and G(2)/M phases, and the arrest occurred initially in G(2)/M phase.


CONCLUSIONS
(32)P may significantly interfere with the cell cycle of HL-60 cells, causing cell cycle arrest primarily in G(2)/M.
He
Zi-Yi
ZY
Center of Analysis, Guangdong Medical College, Zhanjiang 524023, China.
Meng
Qin-Yong
QY
D002453:Cell Cycle / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D005434:Flow Cytometry; D018922:HL-60 Cells; D006801:Humans; D010761:Phosphorus Radioisotopes
D010761:Phosphorus Radioisotopes