Impact of patient risk on the hospital volume-outcome relationship in coronary artery bypass grafting.
BACKGROUND
The impact of surgical risk on the relationship between hospital volume and outcomes in coronary artery bypass grafting (CABG) is uncertain. We assessed (1) whether in-hospital mortality rates differ across lower- and higher-volume hospitals by expected surgical risk and (2) whether high-risk patients are more likely to undergo CABG at low-volume centers.


METHODS
We used clinical data on 27,355 adults who underwent CABG at 68 hospitals in California between 1997 and 1998. Hospitals were divided into low-volume (n=44), medium-volume (n=19), and high-volume (n=5) categories on the basis of tertiles of annual CABG volume. Using hierarchical logistic regression and log-binomial regression models, we assessed for differences in in-hospital mortality rates across hospital volume categories and the likelihood of CABG being performed in each hospital volume category after adjusting for expected surgical risk.


RESULTS
Differences in adjusted in-hospital mortality rates between low- and high-volume centers rose as the expected risk of in-hospital death increased: 0.8% vs 0.4% at the 20th risk percentile and 3.8% vs 2.5% at the 80th risk percentile (P<.001 for all comparisons). While a similar trend was seen between medium- and high-volume centers, absolute differences were substantially smaller. The likelihood of patients having surgery at a low-volume center also rose significantly with expected surgical risk (relative risk of undergoing CABG at a low-volume center for patients at 80th vs 20th risk percentile, 1.29 [95% confidence interval, 1.14-1.51; P<.001]).


CONCLUSIONS
High-risk patients are more likely to undergo CABG at low-volume facilities where their risk of dying is higher.
Nallamothu
Brahmajee K
BK
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, 48109-0366, USA. bnallamo@umich.edu
Saint
Sanjay
S
Hofer
Timothy P
TP
Vijan
Sandeep
S
Eagle
Kim A
KA
Bernstein
Steven J
SJ
D000368:Aged; D002140:California / Q000453:epidemiology; D001026:Coronary Artery Bypass / Q000401:mortality* / Q000706:statistics & numerical data*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D017063:Outcome Assessment, Health Care; D012044:Regression Analysis; D018570:Risk Assessment; D013503:Surgery Department, Hospital / Q000592:standards* / Q000706:statistics & numerical data*