Cognitive function in schizoaffective disorder and clinical subtypes of schizophrenia.
Cognitive studies of patients with Schizoaffective Disorder typically indicate that the cognitive function of these patients resembles that of patients with Schizophrenic Disorder more than it does patients with nonpsychotic Mood Disorder. In this study patients with Schizoaffective Disorder were compared with patients with Paranoid, Undifferentiated and Residual clinical subtypes on a number of measures of cognitive function. Multivariate analyses of variance indicated that the cognitive function of Schizoaffective and Paranoid patients had more intact cognitive function that did Undifferentiated and Residual patients. Application of cluster analysis indicated that there were relative high percentages of Schizoaffective and Paranoid patients in a "Neuropsychologically Normal" cluster. It was concluded that Schizoaffective Disorder as well as other clinical subtypes of schizophrenia are cognitively heterogeneous, and it was suggested that a subgroup of patients with Schizoaffective Disorder may not differ in cognitive ability from patients with nonpsychotic Mood Disorder.
Goldstein
Gerald
G
Research (151R), VA Pittsburgh Healthcare System, 7180 Highland Drive, Pittsburgh, PA 15206, USA. ggold@nb.net
Shemansky
Wendy Jo
WJ
Allen
Daniel N
DN
D000328:Adult; D003072:Cognition Disorders / Q000145:classification / Q000209:etiology*; D006801:Humans; D007361:Intelligence Tests; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000145:classification / Q000150:complications* / Q000523:psychology*; D012016:Reference Values; D015203:Reproducibility of Results; D012559:Schizophrenia / Q000145:classification / Q000150:complications*; D012565:Schizophrenic Psychology