title: Characterization of Sox9 in European Atlantic sturgeon (Acipenser sturio).
abstract: The Sox9 gene of Acipenser sturio, one of the most primitive vertebrates, was analyzed. No sex-specific differences were observed. Sturgeon Sox9 consists of three exons and two introns with completely conserved exon-intron boundaries showing high levels of homology to other vertebrate Sox9 sequences, especially in the N-terminus region containing the HMG box. We found strong evidence for negative (purifying) selection. In contrast to previous studies of other fishes, we observed no evidence for gene duplication in sturgeon. Phylogenetic analyses of Sox9 evolution revealed a basal position for sturgeon Sox9.
authors.affiliation: Department of Evolutionary Genetics, Leibniz-Institute for Zoo and Wildlife Research, Alfred-Kowalke-Strasse 17, 10315 Berlin, Germany.
authors.forename: A K
authors.initials: AK
authors.lastname: Hett
authors.forename: C
authors.initials: C
authors.lastname: Pitra
authors.forename: I
authors.initials: I
authors.lastname: Jenneckens
authors.forename: A
authors.initials: A
authors.lastname: Ludwig
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D016000:Cluster Analysis; D017931:DNA Primers; D005399:Fishes / Q000235:genetics*; D005602:France; D040461:Gene Components; D006609:High Mobility Group Proteins / Q000235:genetics*; D016013:Likelihood Functions; D008957:Models, Genetic; D008969:Molecular Sequence Data; D010802:Phylogeny; D045483:Rivers; D055758:SOX9 Transcription Factor; D012641:Selection, Genetic; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D017931:DNA Primers; D006609:High Mobility Group Proteins; D055758:SOX9 Transcription Factor; D014157:Transcription Factors