Ultrahigh-resolution optical coherence tomography in glaucoma.
OBJECTIVE
Optical coherence tomography (OCT) has been shown to be a valuable tool in glaucoma assessment. We investigated a new ultrahigh-resolution OCT (UHR-OCT) imaging system in glaucoma patients and compared the findings with those obtained by conventional-resolution OCT.


METHODS
Retrospective comparative case series.


METHODS
A normal subject and 4 glaucoma patients representing various stages of glaucomatous damage.


METHODS
All participants were scanned with StratusOCT (axial resolution of approximately 10 mum) and UHR-OCT (axial resolution of approximately 3 microm) at the same visit.


METHODS
Comparison of OCT findings detected with StratusOCT and UHR-OCT.


RESULTS
Ultrahigh-resolution OCT provides a detailed cross-sectional view of the scanned retinal area that allows differentiation between retinal layers. These UHR images were markedly better than those obtained by the conventional-resolution OCT.


CONCLUSIONS
Ultrahigh-resolution OCT provides high-resolution images of the ocular posterior segment, which improves the ability to detect retinal abnormalities due to glaucoma.
Wollstein
Gadi
G
New England Eye Center, Tufts-New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA.
Paunescu
Leila A
LA
Ko
Tony H
TH
Fujimoto
James G
JG
Kowalevicz
Andrew
A
Hartl
Ingmar
I
Beaton
Siobahn
S
Ishikawa
Hiroshi
H
Mattox
Cynthia
C
Singh
Omah
O
Duker
Jay
J
Drexler
Wolfgang
W
Schuman
Joel S
JS
D000328:Adult; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D009898:Optic Disk / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D010865:Pilot Projects; D012165:Retinal Ganglion Cells / Q000473:pathology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods*