[A novel translocation t(1;18)(p31;p11) in a patient with myelodysplastic syndrome].
OBJECTIVE
To report a case of myelodysplastic syndrome(MDS) with t(1;18)(p31;p11).


METHODS
Chromosome specimens were prepared by short-term culture of bone marrow cells. Karyotype analysis was made by R banding technique. Chromosome painting was performed using whole chromosome probes 1 and 18.


RESULTS
Conventional karyotype analysis revealed t(1;18)(p31;p11) in this patient. Chromosome painting analysis confirmed this result.


CONCLUSIONS
The translocation of (1;18) was an unusual recurrent chromosome change and was reported on MDS for the first time.
Du
Bing
B
Department of Hematology, the Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu, 221002 PR China.
Wu
Ya-fang
YF
Pan
Jin-lan
JL
Xue
Yong-quan
YQ
D000328:Adult; D002878:Chromosomes, Human, Pair 1; D002887:Chromosomes, Human, Pair 18; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D008297:Male; D009190:Myelodysplastic Syndromes / Q000235:genetics*; D014178:Translocation, Genetic / Q000235:genetics*