title: [Study on purification technology of patchouly oil with molecular distillation].
abstract: OBJECTIVE
  To establish an advanced purification techniques of the essential oils obtained from Pogostemon cablin.
  
  
  METHODS
  Molecular distillation (MD) was applied.
  
  
  RESULTS
  Four distillates were obtained, chemical constituents of which were analyzed with GC-MS. Compared with those in original oils, the contents of active compounds (patchouli alcohol and pogostone) rose by 27%-47% in the distillates II and III.
  
  
  CONCLUSIONS
  Molecular distillation (MD) effectively raises the contents of patchouli alcohol and pogostone. The work is of great economic and scientific significance for the industrialization of P. cablin and the discovery of new drugs.
authors.affiliation: School of Pharmaceutical Sciences, Sun Yat-san University, Guangzhou 510275, China.
authors.forename: Hai-yan
authors.initials: HY
authors.lastname: Hu
authors.forename: Jin-fu
authors.initials: JF
authors.lastname: Peng
authors.forename: Shi-liang
authors.initials: SL
authors.lastname: Huang
authors.forename: Li-hong
authors.initials: LH
authors.lastname: Wu
authors.forename: Bao-zhang
authors.initials: BZ
authors.lastname: Zhu
authors.forename: Yao-ming
authors.initials: YM
authors.lastname: Xuan
authors.forename: De-po
authors.initials: DP
authors.lastname: Yang
mesh_terms: D008401:Gas Chromatography-Mass Spectrometry; D019686:Lamiaceae / Q000737:chemistry*; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry; D012717:Sesquiterpenes / Q000302:isolation & purification*; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D009822:Oils, Volatile; C483658:Pogostone; D012717:Sesquiterpenes; C052983:patchouli alcohol