title: Effects of epidural anaesthesia-analgesia on intravenous anaesthesia with propofol.
abstract: The main purpose of this study was to demonstrate that the use of epidural anaesthesia-analgesia reduces the amount of propofol necessary to maintain surgical anaesthesia in dogs during ovariohysterectomy. The study was carried out on 28 bitches undergoing ovariohysterectomy with general anaesthesia using an intravenous infusion of propofol. Dogs were allocated to one of two groups. Group 1 received systemic buprenorphine together with epidural analgesia using lidocaine and buprenophine, and in Group 2 systemic buprenorphine only was given. The mean propofol infusion rate was significantly lower in dogs with epidural analgesia (P < 0.0001). In addition, the mean endotracheal extubation time was significantly longer in dogs with epidural analgesia (P < 0.0001). No significant differences were detected in any of the physiological parameters measured.
authors.affiliation: Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Autonomous University of Barcelona, Bellaterra, Barcelona 08193, Spain.
authors.forename: J M
authors.initials: JM
authors.lastname: Tusell
authors.forename: A
authors.initials: A
authors.lastname: Andaluz
authors.forename: D
authors.initials: D
authors.lastname: Prandi
authors.forename: C
authors.initials: C
authors.lastname: Costa
authors.forename: F
authors.initials: F
authors.lastname: García
mesh_terms: D015360:Analgesia, Epidural / Q000662:veterinary*; D000701:Analgesics, Opioid / Q000008:administration & dosage; D000767:Anesthesia, Epidural / Q000662:veterinary*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002047:Buprenorphine / Q000008:administration & dosage; D004285:Dogs / Q000502:physiology* / Q000601:surgery; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D007044:Hysterectomy / Q000379:methods / Q000662:veterinary; D008012:Lidocaine / Q000008:administration & dosage; D010052:Ovariectomy / Q000379:methods / Q000662:veterinary; D015742:Propofol / Q000008:administration & dosage*; D011897:Random Allocation; D012119:Respiration / Q000187:drug effects
chemical_list: D000701:Analgesics, Opioid; D018686:Anesthetics, Intravenous; D002047:Buprenorphine; D008012:Lidocaine; D015742:Propofol