title: Fatal variceal rupture after sildenafil use: report of a case.
abstract: Sildenafil may increase the risk of variceal bleeding in portal hyptertension by increasing splanchnic blood flow. We report herein the second case of variceal rupture after sildenafil use.
authors.affiliation: Division of Hepatobiliary and Pancreas Surgery, Department of Surgery, University of California, Irvine, Orange, California 92868, USA. finds@uci.edu
authors.forename: David S
authors.initials: DS
authors.lastname: Finley
authors.forename: Brian
authors.initials: B
authors.lastname: Lugo
authors.forename: James
authors.initials: J
authors.lastname: Ridgway
authors.forename: Wang
authors.initials: W
authors.lastname: Teng
authors.forename: David K
authors.initials: DK
authors.lastname: Imagawa
mesh_terms: D015106:3',5'-Cyclic-GMP Phosphodiesterases / Q000037:antagonists & inhibitors*; D000328:Adult; D017809:Fatal Outcome; D006465:Hemoperitoneum / Q000209:etiology*; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications; D008297:Male; D009852:Omentum / Q000098:blood supply*; D010726:Phosphodiesterase Inhibitors / Q000009:adverse effects*; D010879:Piperazines / Q000009:adverse effects*; D011687:Purines; D012422:Rupture, Spontaneous; D000068677:Sildenafil Citrate; D013450:Sulfones; D014648:Varicose Veins / Q000503:physiopathology*; D014665:Vasodilator Agents / Q000009:adverse effects*
chemical_list: D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate; D015106:3',5'-Cyclic-GMP Phosphodiesterases