title: YPL.db2: the Yeast Protein Localization database, version 2.0.
abstract: The Yeast Protein Localization database (YPL.db(2)) is an archive of microscopic image data of protein localization patterns in the yeast Saccharomyces cerevisiae. The current version of YPL.db(2) harbours 500 sets of image data derived from high-resolution microscopic analyses of proteins tagged with the green fluorescent protein (GFP). Major functional improvements in YPL.db(2) over a previous release are a web-based experiment and image submission interface, facilitating standardized data entry by remote users through the Internet. The image display page provides image gallery and image scrolling features. In addition, fluorescence and transmission images can be superimposed, allowing image fading for precise correlation of the protein's localization in the cellular context. The reference structure database displaying 'prototypic' localization patterns was extended, and a feature to display and manipulate 3D-image datasets, using a freely available VRML plug-in, was included. Access to the Yeast Protein Localization database version 2.0 (YPL.db(2)) is available through http://YPL.uni-graz.at.
authors.affiliation: SFB Biomembrane Research Center, Institute of Molecular Biosciences, University of Graz, Schubertstrasse 1, A8010 Graz, Austria. sepp.kohlwein@uni-graz.at
authors.forename: Mathias
authors.initials: M
authors.lastname: Kals
authors.forename: Klaus
authors.initials: K
authors.lastname: Natter
authors.forename: Gerhard G
authors.initials: GG
authors.lastname: Thallinger
authors.forename: Zlatko
authors.initials: Z
authors.lastname: Trajanoski
authors.forename: Sepp D
authors.initials: SD
authors.lastname: Kohlwein
mesh_terms: D030562:Databases, Protein; D049452:Green Fluorescent Proteins / Q000378:metabolism; D016247:Information Storage and Retrieval / Q000379:methods; D012441:Saccharomyces cerevisiae / Q000378:metabolism* / Q000648:ultrastructure; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism*
chemical_list: D029701:Saccharomyces cerevisiae Proteins; D049452:Green Fluorescent Proteins