The discovery of a multi-resistant Staphylococcus haemolyticus clone in the hospital and community environment in south western Nigeria.
Among clinically significant isolates of coagulase negative staphylococci, Staphylococcus haemolyticus is ranked second after Staphylococcus epidermidis. It has been associated with septicemia in newborns and various infections in persons with compromised host defenses and implanted foreign bodies. The existence of a multi-resistant Staphylococcus haemolyticus clone was discovered during a study on patients with skin and soft tissue infections at two local health clinics and in a referral hospital in South Western Nigeria. The clonal nature of these strains was determined by antibiotic susceptibility profile and pulsed field gel electrophoresis. This represents the first report of what appears to be a hospital-acquired and transmitted Staphylococcus haemolyticus clone in South Western Nigeria. Careful infection control measures and strain typing are urgently needed to understand species epidemiology and to limit the spread of multi-resistant strains within and beyond healthcare facilities.
Shittu
Adebayo Osagie
AO
School of Biochemistry and Microbiology, University of KwaZulu Natal, Republic of South Africa.
Lin
Johnson
J
Morrison
Donald
D
Kolawole
Deboye Oriade
DO
D000046:Academic Medical Centers; D002353:Carrier State / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology* / Q000517:prevention & control; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology* / Q000517:prevention & control; D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D017053:Infection Control / Q000379:methods / Q000592:standards; D008826:Microbial Sensitivity Tests; D009297:Nasal Mucosa / Q000382:microbiology; D009549:Nigeria / Q000453:epidemiology; D016133:Polymerase Chain Reaction; D011159:Population Surveillance; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology* / Q000517:prevention & control; D041162:Staphylococcus haemolyticus / Q000235:genetics / Q000302:isolation & purification
D004269:DNA, Bacterial