title: [Expression of PDGF-B after fluid percussion brain injury in rats].
abstract: OBJECTIVE
  To elucidate the changes of PDGF-B chain in the brain injured by fluid percussion.
  
  
  METHODS
  The expression of PDGF-B protein was studied by immunohistochemistry and the results were assessed by image analysis system.
  
  
  RESULTS
  Enhanced expression of PDGF-B protein induced by fluid percussion injury was seen at 1 h, and its marked up-regulation was noted at 4-7 days, and then the expression became decreased but it remained above the control levels till 14 days after injury.
  
  
  CONCLUSIONS
  Fluid percussion brain injury induced expression of PDGF-B. The regular change pattern of PDGF-B level in time course seems to be of value in estimating the age of brain injury.
authors.affiliation: Department of Forensic Pathology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
authors.forename: Lei-bo
authors.initials: LB
authors.lastname: Li
authors.forename: Xiao-gang
authors.initials: XG
authors.lastname: Chen
authors.forename: Min
authors.initials: M
authors.lastname: Liu
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
authors.forename: Shi-chun
authors.initials: SC
authors.lastname: Wang
authors.forename: Zhi-gang
authors.initials: ZG
authors.lastname: Liao
authors.forename: Gui-qiong
authors.initials: GQ
authors.lastname: He
mesh_terms: D000818:Animals; D001930:Brain Injuries / Q000378:metabolism*; D049429:Forensic Pathology; D008297:Male; D020574:Proto-Oncogene Proteins c-sis / Q000096:biosynthesis* / Q000235:genetics; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D015854:Up-Regulation
chemical_list: D020574:Proto-Oncogene Proteins c-sis