title: Correlation between nasosinusal symptoms and topographic diagnosis in chronic rhinosinusitis.
abstract: Rhinitis and sinusitis concern roughly a quarter of the population in the Western world. They are associated with a wide range of symptoms: nasal obstruction, anterior and posterior nasal discharge, sneezing episodes, facial pain or congestion, and taste and smell disorders. The aim of this prospective study was to evaluate the clinical significance of these various symptoms as a function of the topographic diagnosis of chronic rhinosinusitis. The study involved 474 patients with signs of chronic perennial and persistent rhinosinusitis. The disorders of the nasal cavities and paranasal sinuses were classified into three main diagnostic categories: chronic rhinitis, localized sinusitis (mainly, anterior sinusitis), and diffuse rhinosinusitis (ie, nasal polyposis). A principal components analysis was performed. The symptom patterns of the three main clinical entities differed greatly. Most of the following clinical signs--nasal obstruction, anterior and posterior nasal discharge, sneezing, and facial congestion--are found in all diagnostic categories and hold no specific clinical significance. By contrast, four symptoms seem to have a substantial differentiating potential: anosmia and complete loss of flavor for diffuse rhinosinusitis, cacosmia for localized anterior sinusitis, and severe facial pain for localized sinusitis. This study proposes a new analysis of the relationship between symptoms of chronic rhinosinusitis and findings on a sinus computed tomography scan.
authors.affiliation: Department of Otolaryngology, European Hospital Georges Pompidou, Paris, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Bonfils
authors.forename: Philippe
authors.initials: P
authors.lastname: Halimi
authors.forename: Catherine
authors.initials: C
authors.lastname: Le Bihan
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Norès
authors.forename: Paul
authors.initials: P
authors.lastname: Avan
authors.forename: Paul
authors.initials: P
authors.lastname: Landais
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D005157:Facial Pain / Q000209:etiology; D006801:Humans; D008875:Middle Aged; D009297:Nasal Mucosa / Q000378:metabolism; D015508:Nasal Obstruction / Q000209:etiology; D000857:Olfaction Disorders / Q000209:etiology; D010256:Paranasal Sinuses / Q000000981:diagnostic imaging*; D011446:Prospective Studies; D012220:Rhinitis / Q000175:diagnosis*; D012852:Sinusitis / Q000175:diagnosis*; D012912:Sneezing; D011795:Surveys and Questionnaires; D013651:Taste Disorders / Q000209:etiology; D014057:Tomography, X-Ray Computed