title: First confirmed case of vancomycin-resistant Enterococcus faecium meningitis in Turkey: case report and literature review.
abstract: Vancomycin-resistant enterococci are unusual etiologic agents of bacterial meningitis and pose significant therapeutic difficulties. We report the first confirmed case of nosocomial vancomycin-resistant Enterococcus faecium meningitis in Turkey. The patient was treated with chloramphenicol and cerebrospinal fluid cultures became negative, but clinical success was not achieved. We also review the previously reported cases of vancomycin-resistant Enterococcus faecium meningitis.
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Akdeniz University, Medicine Faculty, Antalya, Turkey. inan@akdeniz.edu.tr
authors.forename: D
authors.initials: D
authors.lastname: Inan
authors.forename: F
authors.initials: F
authors.lastname: Gunseren
authors.forename: D
authors.initials: D
authors.lastname: Colak
authors.forename: R
authors.initials: R
authors.lastname: Saba
authors.forename: S
authors.initials: S
authors.lastname: Kazan
authors.forename: L
authors.initials: L
authors.lastname: Mamikoglu
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002555:Cerebrospinal Fluid / Q000382:microbiology; D002701:Chloramphenicol / Q000627:therapeutic use; D003428:Cross Infection / Q000188:drug therapy; D016984:Enterococcus faecium / Q000187:drug effects* / Q000472:pathogenicity*; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D014421:Turkey; D020713:Vancomycin Resistance
chemical_list: D000900:Anti-Bacterial Agents; D002701:Chloramphenicol