title: A sensitive biosensor for lactate based on layer-by-layer assembling MnO2 nanoparticles and lactate oxidase on ion-sensitive field-effect transistors.
abstract: A sensitive enzyme-based FET biosensor for lactate has been obtained by introducing MnO2 nanoparticles at the gate surface via a layer-by-layer assembling method.
authors.affiliation: Key Lab of Analytical Chemistry for Life Science, Department of Chemistry, Nanjing University, Nanjing 210093, China. xujj@nju.edu.cn
authors.forename: Jing-Juan
authors.initials: JJ
authors.lastname: Xu
authors.forename: Wei
authors.initials: W
authors.lastname: Zhao
authors.forename: Xi-Liang
authors.initials: XL
authors.lastname: Luo
authors.forename: Hong-Yuan
authors.initials: HY
authors.lastname: Chen
mesh_terms: D018441:Biofilms; D015374:Biosensing Techniques; D004800:Enzymes, Immobilized; D019344:Lactic Acid / Q000737:chemistry*; D017895:Manganese Compounds / Q000737:chemistry*; D006899:Mixed Function Oxygenases / Q000737:chemistry* / Q000378:metabolism; D049329:Nanostructures; D036103:Nanotechnology / Q000295:instrumentation* / Q000379:methods; D010087:Oxides / Q000737:chemistry*; D012815:Signal Processing, Computer-Assisted; D014173:Transistors, Electronic
chemical_list: D004800:Enzymes, Immobilized; D017895:Manganese Compounds; D010087:Oxides; D019344:Lactic Acid; D006899:Mixed Function Oxygenases; C021497:lactate 2-monooxygenase; C016552:manganese dioxide