Chagas' disease: study of congenital transmission in cases of acute maternal infection.
We studied three pregnant women with acute chagasic infection. Two patients, infected in the third trimester of pregnancy, had uninfected children. The third patient, infected earlier, had an infected newborn. These results encourage research on risk factors of transmission and on medical decisions concerning pregnant women with acute Chagas' disease.
Moretti
Edgardo
E
Departamento Diagnóstico y Tratamiento, Servicio Nacional de Chagas, Córdoba, Argentina. ebi@fcm.unc.edu.ar
Basso
Beatriz
B
Castro
Irma
I
Carrizo Paez
Mario
M
Chaul
Marcela
M
Barbieri
Gustavo
G
Canal Feijoo
Dámaso
D
Sartori
María José
MJ
Carrizo Paez
Rubén
R
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D014355:Chagas Disease / Q000151:congenital / Q000635:transmission*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D009593:Nitroimidazoles / Q000627:therapeutic use; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000469:parasitology; D011261:Pregnancy Trimester, First; D011263:Pregnancy Trimester, Third; D012307:Risk Factors; D014344:Trypanocidal Agents / Q000627:therapeutic use
D009593:Nitroimidazoles; D014344:Trypanocidal Agents; C009999:benzonidazole