[Vascular effects of physical activity].
Regular physical activity decelerates the aging processes of the arterial wall and of the endothelial functions, which is denoted with slackening of the propagation velocity of the pulse wave or by echo checking of the postischemic dilatation of the limb vessels. Of the factors evoking, organizing and executing the dilation and constriction of the arteries, the role of the endothelial nitrogen oxide, of the angiogenesis, and of the balance of the hemostasis seems to be the most important and best recognized. Even few months of training program improves the endothelial functions if the amount and the intensity suits to the recommended in cardiovascular diseases. Physical training is a very effective course for prevention and rehabilitation in various conditions incidental to endothelial dysfunction. Damaged endothelial function predisposes to local thrombotic events. Thrombogenic prevalence can be normalized by physical activity at many steps of the hemostasis: activated fibrinolysis, more favorable blood viscosity, lower plasminogen activator inhibitor (PAI-1) level, decreased platelet activity.
Apor
Péter
P
Semmelweis Egyetem Testnevelés es Sporttudományi Kar, Budapest. p.apor.md@freemail.hu
Rádi
Attila
A
D002318:Cardiovascular Diseases / Q000503:physiopathology; D003920:Diabetes Mellitus / Q000503:physiopathology; D004730:Endothelium, Vascular / Q000502:physiology; D015444:Exercise / Q000502:physiology*; D006487:Hemostasis; D006801:Humans; D009043:Motor Activity / Q000502:physiology*; D018919:Neovascularization, Physiologic; D014664:Vasodilation