title: Immunity: it's in our bones.
abstract: Accumulating data suggest that the bone marrow is a reservoir for memory CD8+ T cells. In this issue of Immunity, show that bone marrow CD8+ T cells are predominantly CCR7+/CD62L+ "central memory" cells and describe specific signals that mediate their constitutive recruitment from the blood.
authors.affiliation: Trudeau Institiute, Inc., Saranac Lake, NY 12983, USA.
authors.forename: David L
authors.initials: DL
authors.lastname: Woodland
authors.forename: Marcia A
authors.initials: MA
authors.lastname: Blackman
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000276:immunology*; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology* / Q000378:metabolism; D006801:Humans; D007156:Immunologic Memory / Q000276:immunology*; D015398:Signal Transduction