title: Follicular thyroid lesions, elements that affect both diagnosis and prognosis.
abstract: The precise diagnosis of follicular thyroid lesions is frequently debated because of the subjective nature of capsular invasion as well as both the histological and cytological characteristics. Furthermore, several different prognostic indices have been devised to examine prognosis associated with thyroid cancer. Herein, we describe how these confounding elements can affect the ability to accurately predict prognosis for patients with follicular thyroid lesions.
authors.affiliation: Department of Surgery, Division of Endocrine and Oncologic Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA. mzeiger@jhmi.edu
authors.forename: Martha A
authors.initials: MA
authors.lastname: Zeiger
authors.forename: Alan P B
authors.initials: AP
authors.lastname: Dackiw
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000175:diagnosis / Q000473:pathology; D000236:Adenoma / Q000175:diagnosis* / Q000473:pathology; D014408:Biomarkers, Tumor / Q000032:analysis; D002291:Carcinoma, Papillary / Q000175:diagnosis* / Q000473:pathology; D018265:Carcinoma, Papillary, Follicular / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D037502:Galectin 3 / Q000032:analysis; D006801:Humans; D007633:Keratins / Q000032:analysis; D008207:Lymphatic Metastasis; D009361:Neoplasm Invasiveness; D011379:Prognosis; D013964:Thyroid Neoplasms / Q000145:classification / Q000175:diagnosis* / Q000473:pathology
chemical_list: D014408:Biomarkers, Tumor; D037502:Galectin 3; D007633:Keratins