title: Experimental bacteriophage protection against Staphylococcus aureus abscesses in a rabbit model.
abstract: In a rabbit model of wound infection caused by Staphylococcus aureus, 2 x 10(9) PFU of staphylococcal phage prevented abscess formation in rabbits when it was injected simultaneously with S. aureus (8 x 10(7) CFU) into the same subcutaneous site. Phage multiplied in the tissues. Phages might be a valuable prophylaxis against staphylococcal infection.
authors.affiliation: Infectious Diseases and Microbiology Unit, Institute of Child Health, University College London, UK.
authors.forename: Quintin F
authors.initials: QF
authors.lastname: Wills
authors.forename: Claire
authors.initials: C
authors.lastname: Kerrigan
authors.forename: James S
authors.initials: JS
authors.lastname: Soothill
mesh_terms: D000038:Abscess / Q000382:microbiology / Q000517:prevention & control* / Q000821:virology; D000818:Animals; D015169:Colony Count, Microbial; D004195:Disease Models, Animal; D011817:Rabbits; D013203:Staphylococcal Infections / Q000382:microbiology / Q000517:prevention & control* / Q000821:virology; D013204:Staphylococcus Phages; D014946:Wound Infection / Q000382:microbiology / Q000517:prevention & control* / Q000821:virology
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