title: Removing eye-movement artifacts from the EEG during the intracarotid amobarbital procedure.
abstract: OBJECTIVE
  The EEG is often recorded during the intracarotid amobarbital procedure (IAP) to help in the assessment of the spatial extent and the duration of the effect of the drug. In scalp recordings, the EEG is always heavily contaminated with eye movement artifacts as the patient actively performs visual tasks.
  
  
  METHODS
  Independent component analysis (ICA) is a new technique for blind source separation. In this study, we separated the EEG data recorded during the IAP into independent components using ICA. The EEG signal was reconstructed by excluding the components related to eye movement and eye blinks.
  
  
  RESULTS
  EEGs from 10 IAP tests were analyzed. The experimental results indicate that ICA is very efficient at subtracting eye-movement artifacts, while retaining the EEG slow waves and making their interpretation easier.
  
  
  CONCLUSIONS
  ICA appears to be a generally applicable and effective method for removing ocular artifacts from EEG recordings during IAP, although slow waves and ocular artifacts share similar frequency distributions.
authors.affiliation: Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
authors.forename: Weidong
authors.initials: W
authors.lastname: Zhou
authors.forename: Jean
authors.initials: J
authors.lastname: Gotman
mesh_terms: D000465:Algorithms; D000654:Amobarbital / Q000008:administration & dosage / Q000494:pharmacology; D016477:Artifacts; D001767:Blinking / Q000187:drug effects / Q000502:physiology; D001931:Brain Mapping; D002343:Carotid Artery, Internal; D004569:Electroencephalography / Q000379:methods / Q000706:statistics & numerical data*; D004827:Epilepsy / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D005133:Eye Movements / Q000502:physiology*; D007839:Functional Laterality / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007269:Injections, Intra-Arterial; D007802:Language; D008568:Memory / Q000187:drug effects / Q000502:physiology; D016571:Neural Networks, Computer; D011300:Preoperative Care; D012815:Signal Processing, Computer-Assisted
chemical_list: D000654:Amobarbital