title: Colorectal cancer screening: prospects for molecular stool analysis.
abstract: Colorectal cancer is common. As many patients present with advanced disease, an effective screening test would have substantial clinical benefits. Recent progress in understanding the biology of colorectal cancer (and of cancer cells in general) has led to possible new approaches to screening. In particular, there are prospects of developing tests based on analysis of stool, which promise improved accuracy, safety, affordability and patient compliance.
authors.affiliation: Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, Hills Road, Cambridge, CB2 2XZ, UK.
authors.forename: R Justin
authors.initials: RJ
authors.lastname: Davies
authors.forename: Richard
authors.initials: R
authors.lastname: Miller
authors.forename: Nicholas
authors.initials: N
authors.lastname: Coleman
mesh_terms: D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000235:genetics* / Q000473:pathology; D004273:DNA, Neoplasm; D005243:Feces; D005819:Genetic Markers; D006801:Humans; D008403:Mass Screening / Q000639:trends*; D009360:Neoplastic Cells, Circulating; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D004273:DNA, Neoplasm; D005819:Genetic Markers