Pupil reaction: a valid sensitive clinical biomarker for 5-HT compounds.
Boettcher
Michael
M
Institute of Clinical Pharmacology, Bayer HealthCare AG, Aprather Weg 18a, D-42096 Wuppertal, Germany. rich.boettcher@bayerhealthcare.com
Heinig
Roland
R
Wensing
Georg
G
Kuhlmann
Jochen
J
D000293:Adolescent; D000328:Adult; D001578:Benzopyrans / Q000494:pharmacology*; D015415:Biomarkers; D006801:Humans; D008297:Male; D008875:Middle Aged; D011680:Pupil / Q000187:drug effects*; D058825:Serotonin 5-HT1 Receptor Agonists; D013844:Thiazoles / Q000494:pharmacology*
D001578:Benzopyrans; D015415:Biomarkers; D058825:Serotonin 5-HT1 Receptor Agonists; D013844:Thiazoles; C111221:repinotan hydrochloride