[Use of the solutions of hydroxyethyl starch and reamberin in the combined treatment of severe gestosis].
The effects of the solutions of hydroethyl starch (HES) and reamberin on hemodynamics, metabolism, and water-sector disorders were studied in patients with severe gestosis. The study covered 42 puerperas who were divided into 3 groups: 1) 10 patients with severe gestosis and normal acid-alkali balance (AAB); 2) 10 with severe gestosis and metabolic acidosis; 3) 22 pueperas with physiological single pregnancy (a control group). Group 1 patients were given infusions of 6% HES solution, 5-6 ml/kg; Group 2 received in addition to 6% HES solution in the above dose infusions of 1.5% reamberin solution, 5 ml/kg. In patients with severe gestosis, hemodynamic, water-sector, and metabolic monitoring on puerperal days 1-5 were found to identify changes in oxygen supply and consumption, water balance, and AAB. In Group 1 patients, HES infusion on days 1-2 after delivery decreased the content of systemic water, extracellular and interstitial fluid, increased oxygen supply; in Group 2, combined infusion therapy with GES and reamberin on puerperal days 1-2 led to an increase in oxygen supply and consumption and a reduction in interstitial hyperhydration and to normalization of AAB.
Galushka
S V
SV
Nazarov
B F
BF
Vlasenko
A V
AV
D000136:Acid-Base Equilibrium; D001774:Blood Chemical Analysis; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000627:therapeutic use*; D010101:Oxygen Consumption; D011225:Pre-Eclampsia / Q000188:drug therapy*; D011247:Pregnancy; D012996:Solutions; D019802:Succinic Acid / Q000627:therapeutic use*
D006895:Hydroxyethyl Starch Derivatives; D012996:Solutions; D019802:Succinic Acid