The histological aspects of fillers complications.
The histological aspects of resorbable heterologous fillers (bovine collagen, acid hyaluronique), autologous fillers (lipofilling, dermis-fat graft), biodegradable fillers (New-Fill), and permanent fillers (silicone, Artecoll, Evolution, Aquamid, DermaLive, DermaDeep, Bioplastique, Paraffin) are described. This article relates the morphological aspect of these materials, the normal tissue reaction after injection, and its chronological evolution as the morphological aspects from the different side effects, more frequently observed for the permanent fillers. They mainly consist of granulomatous reactions which may appear long after injection.
Zimmermann
Ute S
US
SCP d'Histopathologie, Paris, France. ute.zimmermann@noos.fr
Clerici
Thierry J
TJ
D000818:Animals; D001672:Biocompatible Materials; D002417:Cattle; D003357:Cosmetic Techniques / Q000009:adverse effects*; D015745:Granuloma, Foreign-Body / Q000139:chemically induced; D006801:Humans; D009336:Necrosis; D019736:Prostheses and Implants / Q000009:adverse effects*; D015595:Skin Aging / Q000187:drug effects*
D001672:Biocompatible Materials