[The emergent role of p38 MAPKs in the regulation of cell cycle].
The p38 MAPKs are members of the MAPK family. Its pathway has been traditionally associated with the stress and immune response. More recently, it has been reported that the p38 MAPKs pathway can also regulate apoptosis and some differentiation process. It can regulate cellular growth and cell cycle checkpoints in different ways depending on the cell type and the stimulus.
Chen
Yi
Y
Division of Anti-tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Science, Chinese Academy of Sciences, Shanghai.
Miao
Ze-Hong
ZH
Ding
Jian
J
D000818:Animals; D017209:Apoptosis / Q000502:physiology; D002453:Cell Cycle / Q000502:physiology*; D018797:Cell Cycle Proteins / Q000378:metabolism* / Q000502:physiology; D002454:Cell Differentiation / Q000502:physiology; D006801:Humans; D013312:Stress, Physiological / Q000201:enzymology; D048051:p38 Mitogen-Activated Protein Kinases / Q000502:physiology*
D018797:Cell Cycle Proteins; D048051:p38 Mitogen-Activated Protein Kinases