Mediated electrochemical measurement of the inhibitory effects of furfural and acetic acid on Saccharomyces cerevisiae and Candida shehatae.
The toxic effects of furfural and acetic acid on two yeasts, Saccharomyces cerevisiae and Candida shehatae, were evaluated using an electrochemical method. Intracellular redox activities were lowered by 40% and 78% for S. cerevisiae and C. shehatae, respectively, by 8 g furfural l(-1), and by 46% and 67%, respectively, by 8 g acetic acid l(-1). The proposed method can accurately measure the effects of inhibitors on cell cultures.
Zhao
Jinsheng
J
Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101 , PR China, zhengyuyang@vip.sina.com.
Wang
Min
M
Yang
Zhenyu
Z
Gong
Qintao
Q
Lu
Yao
Y
Yang
Zhengyu
Z
D019342:Acetic Acid / Q000378:metabolism / Q000494:pharmacology* / Q000633:toxicity; D002175:Candida / Q000187:drug effects* / Q000254:growth & development; D004305:Dose-Response Relationship, Drug; D004563:Electrochemistry / Q000379:methods; D005662:Furaldehyde / Q000378:metabolism / Q000494:pharmacology* / Q000633:toxicity; D006863:Hydrogen-Ion Concentration; D010084:Oxidation-Reduction; D015203:Reproducibility of Results; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000254:growth & development
D005662:Furaldehyde; D019342:Acetic Acid