title: Endometrial evaluation in superovulation programs: relationship with successful outcome.
abstract: It is well known that an adequate endometrial receptivity is required for successful implantation in both natural and assisted reproductive cycles. In particular, a brief "implantation window", during which endometrium undergoes anatomical and molecular changes necessary for embryo implantation, has been observed. The hormonal treatment applied to induce ovulation seems to be able to modify the normal development of the prenidatory endometrium, with possible negative effect on the implantation rate. For this reason, several attempts have been made to identify specific markers of endometrial receptivity, useful for predicting implantation outcome in clinical practice. Even if different histological, immunohistochemical, and ultrasonographic parameters are studied, none unfortunately has been univocally shown to be predictive of pregnancy outcome. Therefore, the evaluation of endometrial receptivity remains a challenge in clinical practice.
authors.affiliation: Cattedra di Fisiopatologia della Riproduzione Umana, Università Cattolica del Sacro Cuore (UCSC), Largo A. Gemelli 8, 00168 Rome, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Tropea
authors.forename: Fiorella
authors.initials: F
authors.lastname: Miceli
authors.forename: Francesca
authors.initials: F
authors.lastname: Minici
authors.forename: Mariateresa
authors.initials: M
authors.lastname: Orlando
authors.forename: Giuseppina
authors.initials: G
authors.lastname: Lamanna
authors.forename: Mariafrancesca
authors.initials: M
authors.lastname: Gangale
authors.forename: Stefania
authors.initials: S
authors.lastname: Catino
authors.forename: Antonio
authors.initials: A
authors.lastname: Lanzone
authors.forename: Rosanna
authors.initials: R
authors.lastname: Apa
mesh_terms: D004717:Endometrium / Q000000981:diagnostic imaging* / Q000502:physiology*; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D010062:Ovulation Induction / Q000379:methods*; D014463:Ultrasonography