title: Toxic and repellent effects of Baccharis salicifolia essential oil on Tribolium castaneum.
abstract: Allelochemical effects were observed when Tribolium castaneum (Herbst) adults were treated with Baccharis salicifolia (Ruiz & Pavon) Pers essential oil. The main biological activities were toxicity and repellence. Terpenes present in the essential oil were identified by GC-MS, and some authentic samples were tested to assess their activity individually. The most acutely toxic compounds after 3 days were beta-pinene and pulegone. Most of the monoterpenes elicited symptoms indicative of neurotoxicity. The most repellent compound was alpha-terpineol. Toxic and repellent effects of chemical derivatives of the major sesquiterpene present in B salicifolia essential oil, as well as a series of monoterpenes, were evaluated in order to investigate structure-activity relationships. The reduced derivatives of the monoterpenes and sesquiterpenes were more repellent that their carbonyl analogues. In addition, unsaturation in the germacrane skeleton enhanced repellent activity.
authors.affiliation: INTEQUI-CONICET, Departamento de Química-Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, Chacabuco y Pedernera, 5700, San Luis, Argentina.
authors.forename: Matías
authors.initials: M
authors.lastname: García
authors.forename: Osvaldo J
authors.initials: OJ
authors.lastname: Donadel
authors.forename: Carlos E
authors.initials: CE
authors.lastname: Ardanaz
authors.forename: Carlos E
authors.initials: CE
authors.lastname: Tonn
authors.forename: Marta E
authors.initials: ME
authors.lastname: Sosa
mesh_terms: D000818:Animals; D031175:Baccharis / Q000737:chemistry*; D007302:Insect Repellents; D007306:Insecticides; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry / Q000494:pharmacology; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D012717:Sesquiterpenes / Q000737:chemistry / Q000494:pharmacology; D014231:Tribolium / Q000502:physiology*
chemical_list: D007302:Insect Repellents; D007306:Insecticides; D039821:Monoterpenes; D009822:Oils, Volatile; D012717:Sesquiterpenes