[Echocardiography--prognosis of the course of infectious endocarditis and long-term survival in this disease].
OBJECTIVE
To determine prognostic opportunities of echocardiography (ECG) in infectious endocarditis (IE) basing on the assessment of microbial vegetations size and degree of valvular failure.


METHODS
Of 114 patients with definite IE (72 male, 42 female), 90 ones had primary and 24 secondary endocarditis. The prospective study included all the survivors in the IE active stage--78 patients.


RESULTS
Vegetations > 1 cm in size were detected in 50.8% patients, < 1 cm--in 49.2%. Hospital lethality in vegetations > 1 cm and < 1 cm was 25.8 and 16.1%, respectively. Thromboembolism rate was 81 and 64.2%, respectively. One-year survival was 78.7 and 71.4%, two-year survival 66.5 and 61.7%, three-year survival 66.5 and 49.4%, five-year survival--51.7 and 32.9% in vegetations < 1 cm and > 1 cm, respectively. Valvular regurgitation of the first degree was in 17.5%, of the second degree--in 41.9%, third-fourth degree--in 36.6% patients. Hospital lethality in mitral valve failure was 32.1%, in aortic and tricuspid failure--17.8 and 11.4%, respectively.


CONCLUSIONS
EchoCG was most effective for predicting thromboembolism and cardiac failure. Valvular regurgitation of the third-fourth degree significantly correlates with severe cardiac failure. ECG is less informative for predicting hospital lethality.
Maslov
S V
SV
Lobanov
M Iu
MIu
Kovalev
Iu R
IuR
D000293:Adolescent; D000328:Adult; D000368:Aged; D015150:Echocardiography, Doppler; D004697:Endocarditis, Bacterial / Q000382:microbiology / Q000401:mortality / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis