title: Immunoprotective properties of transgenic plants expressing E2 glycoprotein from CSFV and cysteine protease from Fasciola hepatica.
abstract: Immune responses were elicited in laboratory animals after oral vaccination by transgenic plants (lettuce and alfalfa) expressing the E2 glycoprotein of Classical Swine Fever Virus (CSFV) or cysteine protease from Fasciola hepatica. ELISA analyses demonstrated that the oral route is effective in inducing a specific antibody response against these antigens in mice.
authors.affiliation: Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704 Poznań, Poland. legocki@ibch.poznan.pl
authors.forename: Andrzej B
authors.initials: AB
authors.lastname: Legocki
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Miedzinska
authors.forename: Magdalena
authors.initials: M
authors.lastname: Czaplińska
authors.forename: Andrzej
authors.initials: A
authors.lastname: Płucieniczak
authors.forename: Halina
authors.initials: H
authors.lastname: Wedrychowicz
mesh_terms: D000818:Animals; D006692:Classical Swine Fever Virus / Q000276:immunology*; D003546:Cysteine Endopeptidases / Q000235:genetics / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005210:Fasciola hepatica / Q000235:genetics / Q000276:immunology*; D007114:Immunization; D007070:Immunoglobulin A / Q000096:biosynthesis; D007074:Immunoglobulin G / Q000096:biosynthesis; D007700:Kinetics; D018545:Lactuca; D000455:Medicago sativa; D051379:Mice; D030821:Plants, Genetically Modified / Q000276:immunology*; D014759:Viral Envelope Proteins / Q000096:biosynthesis* / Q000276:immunology*
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D014759:Viral Envelope Proteins; C087086:glycoprotein E2, classical swine fever virus; D003546:Cysteine Endopeptidases