Long-term follow-up in children with functional hemispherectomy for Rasmussen's encephalitis.
BACKGROUND
Cerebral hemispherectomy has been performed for over 60 years. Multiple variations of functional hemispherectomy have been performed since its inception by Rasmussen. Long-term follow-up for these variations is lacking in the medical literature.


METHODS
We review the long-term follow-up for five children with Rasmussen's encephalitis who underwent a modification of functional hemispherectomy.


RESULTS
The length of follow-up for this cohort ranged from 13 to 23 years (mean 15.6 years). All patients experienced immediate and complete elimination of seizures. Only one patient underwent ventriculoperitoneal shunt placement. All patients are capable of ambulating on their own. Many years following their procedures, this cohort of patients remains seizure free.
Tubbs
R Shane
RS
Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL, USA. rstubbs@uab.edu
Nimjee
Shahid M
SM
Oakes
W Jerry
WJ
D000293:Adolescent; D002648:Child; D004660:Encephalitis / Q000601:surgery*; D005260:Female; D038421:Hemispherectomy / Q000379:methods*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D016896:Treatment Outcome
Neurosurgery. 1995 Mar;36(3):509-15; discussion 515-6
7753351
Neurology. 2003 Jan 14;60(1):140-2
12525740
Pediatr Neurosurg. 2002 Dec;37(6):298-303
12422044
Ann Neurol. 1988 Jul;24(1):27-34
3137858
Neurology. 1958 Jun;8(6):435-45
13566382
Rev Neurol. 1998 Jun;26(154):978-83
9658472
Adv Neurol. 1992;57:419-33
1543071
Pediatr Neurosurg. 2000 Oct;33(4):198-207
11124637
J Neurosurg. 1996 Jun;84(6):903-11
8847583
Mayo Clin Proc. 2003 Mar;78(3):371-8
12630591
Br J Neurosurg. 1988;2(1):73-84
3268166
Childs Nerv Syst. 1999 Aug;15(8):395-402; discussion 403
10447611
J Neurosurg. 2001 Mar;94(3):510-4
11235958
Neuropediatrics. 1998 Jun;29(3):120-3
9706620
Epilepsy Res. 1998 Jun;31(1):13-27
9696297
Arq Neuropsiquiatr. 2002 Jun;60(2-B):378-81
12131935
Neurosurgery. 1995 Nov;37(5):975-81
8559348
AJNR Am J Neuroradiol. 1998 Mar;19(3):445-9
9541296
J Neurosurg. 1989 Feb;70(2):231-9
2492335
Childs Nerv Syst. 1996 Jul;12(7):376-84
8869773