title: [Tibial osteomyelitis following intraosseous infusion: a case report].
abstract: Fluids, medications, and blood products can be rapidly administered via intraosseous infusion under emergency conditions, particularly to pediatric patients aged from 0 to 2 years. A five-month-old infant who had been hospitalized with a diagnosis of sepsis developed swelling and hyperemia at the infusion site 10 days after an intraosseous infusion in the right proximal tibia. Physical examination showed a serous discharge from a fistula on the anteromedial side of the right proximal cruris. Plain radiographs demonstrated periosteal reaction in the right tibia and osteolytic areas in the proximal metaphysis. With a diagnosis of acute osteomyelitis, drainage and medullary irrigation were performed and parenteral antibiotic treatment was initiated. Cultures from the surgical site yielded Candida albicans, upon which fluconazole (8 mg/kg) treatment was administered for four weeks. A complete clinical and radiographic improvement was observed at the end of a 12-month follow-up.
authors.affiliation: Department of Orthopedics and Traumatology (Ortopedi ve Travmatoloji Anabilim Dali), Medicine Faculty of Yüzüncü Yil University, Van, Turkey. alidogan67@hotmail.com
authors.forename: Ali
authors.initials: A
authors.lastname: Doğan
authors.forename: Hasan
authors.initials: H
authors.lastname: Irmak
authors.forename: Mustafa
authors.initials: M
authors.lastname: Harman
authors.forename: Abdullah
authors.initials: A
authors.lastname: Ceylan
authors.forename: Fuat
authors.initials: F
authors.lastname: Akpinar
authors.forename: Nihat
authors.initials: N
authors.lastname: Tosun
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D003428:Cross Infection / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D017148:Infusions, Intraosseous / Q000009:adverse effects*; D008297:Male; D010019:Osteomyelitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D011859:Radiography; D018805:Sepsis / Q000188:drug therapy*; D013977:Tibia
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole