title: Bioactive constituents from Boswellia papyrifera.
abstract: Phytochemical investigation of the stem bark extract of Boswellia papyrifera afforded two new stilbene glycosides, trans-4',5-dihydroxy-3-methoxystilbene-5-O-{alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->6)]-beta-D-glucopyranoside (1), trans-4',5-dihydroxy-3-methoxystilbene-5-O-[alpha-L-rhamnopyranosyl-(1-->6)]-beta-D-glucopyranoside (2), and a new triterpene, 3alpha-acetoxy-27-hydroxylup-20(29)-en-24-oic acid (3), along with five known compounds, 11-keto-beta-boswellic acid (4), beta-elemonic acid (7), 3alpha-acetoxy-11-keto-beta-boswellic acid (8), beta-boswellic acid (9), and beta-sitosterol (10). The stilbene glycosides exhibited significant inhibition of phosphodiesterase I and xanthine oxidase. The triterpenes (3-9) exhibited prolyl endopeptidase inhibitory activities.
authors.affiliation: H. E. J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan.
authors.lastname: Atta-ur-Rahman
authors.forename: Humera
authors.initials: H
authors.lastname: Naz
authors.lastname: Fadimatou
authors.forename: Talat
authors.initials: T
authors.lastname: Makhmoor
authors.forename: Amsha
authors.initials: A
authors.lastname: Yasin
authors.forename: Naheed
authors.initials: N
authors.lastname: Fatima
authors.forename: F N
authors.initials: FN
authors.lastname: Ngounou
authors.forename: S F
authors.initials: SF
authors.lastname: Kimbu
authors.forename: B L
authors.initials: BL
authors.lastname: Sondengam
authors.forename: M Iqbal
authors.initials: MI
authors.lastname: Choudhary
mesh_terms: D029743:Boswellia / Q000737:chemistry*; D002163:Cameroon; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D013267:Stilbenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D004791:Enzyme Inhibitors; D006027:Glycosides; D013267:Stilbenes; D014315:Triterpenes; C498484:trans-4',5-dihydroxy-3-methoxystilbene-5-O-(alpha-L-rhamnopyranosyl-(1-2)-alpha-L-rhamnopyranosyl-(1-6))-beta-D-glucopyranoside; C498485:trans-4',5-dihydroxy-3-methoxystilbene-5-O-(alpha-L-rhamnopyranosyl-(1-6))-beta-D-glucopyranoside