title: A highly efficient synthesis of the FGH ring of micrandilactone A. Application of thioureas as ligands in the Co-catalyzed Pauson-Khand reaction and Pd-catalyzed carbonylative annulation.
abstract: The functionalized FGH ring system of micrandilactone A was successfully constructed in high selectivity and good yields. The key reactions in our strategy are the Co-thiourea-catalyzed stereoselective, intramolecular Pauson-Khand reaction and Pd-thiourea-catalyzed stereoselective, intramolecular annulation. [structure: see text]
authors.affiliation: Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Beijing 100871, China.
authors.forename: Yefeng
authors.initials: Y
authors.lastname: Tang
authors.forename: Yandong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Mingji
authors.initials: M
authors.lastname: Dai
authors.forename: Tuoping
authors.initials: T
authors.lastname: Luo
authors.forename: Lujiang
authors.initials: L
authors.lastname: Deng
authors.forename: Jiahua
authors.initials: J
authors.lastname: Chen
authors.forename: Zhen
authors.initials: Z
authors.lastname: Yang
mesh_terms: D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D018360:Crystallography, X-Ray; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry*; D008024:Ligands; D008968:Molecular Conformation; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D031363:Scutellaria / Q000737:chemistry; D013890:Thiourea / Q000031:analogs & derivatives* / Q000737:chemistry*; D014315:Triterpenes / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D007783:Lactones; D008024:Ligands; D014315:Triterpenes; C476501:micrandilactone A; D003035:Cobalt; D010165:Palladium; D013890:Thiourea