title: [Anesthesia for a pediatric patient with Coffin-Siris syndrome].
abstract: A 3-year-old boy with Coffin-Siris syndrome was scheduled to undergo diagnostic laparoscopy, inguinal herniorrhaphy and orchiopexy at an ambulatory setting and same-day admission. Following anesthesia induction with inhalational sevoflurane, upper airway obstruction and hypoxemia developed. Hypoxemia was resolved immediately by manual positive pressure ventilation, although the stomach became bulged. Operation was finished uneventfully. However, he had massive bronchial secretion during anesthesia. He was admitted as planned and discharged on postoperative day 2. Since patients with Coffin-Siris syndrome have potential airway and pulmonary dysfunctions, careful perianesthesia airway and respiratory managements are essential.
authors.affiliation: Department of Anesthesia, Kyoto University Hospital, Kyoto 606-8507.
authors.forename: Gotaro
authors.initials: G
authors.lastname: Shirakami
authors.forename: Misako
authors.initials: M
authors.lastname: Tazuke-Nishimura
authors.forename: Hideo
authors.initials: H
authors.lastname: Hirakata
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Fukuda
mesh_terms: D000402:Airway Obstruction; D000768:Anesthesia, General / Q000379:methods*; D002675:Child, Preschool; D003456:Cryptorchidism / Q000601:surgery; D005145:Face / Q000002:abnormalities*; D005385:Fingers / Q000002:abnormalities*; D006130:Growth Disorders; D006552:Hernia, Inguinal / Q000601:surgery; D006801:Humans; D008607:Intellectual Disability; D007431:Intraoperative Complications; D008297:Male; D019990:Perioperative Care; D012141:Respiratory Tract Infections; D013577:Syndrome; D013737:Testis / Q000601:surgery