A new antipsychotic effective neolignan from Firmiana simplex.
A new neolignan, named simplidin was isolated from the the n-butanol extract of stem of Firmiana simplex, together with six known compounds, scopoletin (1), syrigaresinol (2), aquillochin (3), nitidanin (4), tamarixetin 3-rhamnoside (6), and quercitrin (7). On the basis of spectral and chemical evidence, simplidin (5) was determined to be rel-(7R,8R)-4,5,9,9'-tetrahydroxy-3,3'-dimethoxy-7-O-5',8-O-4'-neolignan. All the six compounds were also isolated for the first time from this plant.
Son
Yeon Kyoung
YK
Natural Products Research Institute, Seoul 110-460, Korea.
Lee
Ming Hong
MH
Han
Yong Nam
YN
D014150:Antipsychotic Agents / Q000737:chemistry* / Q000302:isolation & purification*; D017705:Lignans / Q000737:chemistry* / Q000302:isolation & purification*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018547:Plant Stems; D032361:Sterculia
D014150:Antipsychotic Agents; D017705:Lignans; D010936:Plant Extracts