title: Computerised analysis of auscultatory sounds associated with vascular patency of haemodialysis access.
abstract: Vascular access for renal dialysis is a lifeline for about 120 000 individuals in the United States. Stethoscope auscultation of vascular sounds has some utility in the assessment of access patency, yet can be highly skill-dependent. The objective of the study was to identify acoustic parameters that are related to changes in vascular access patency. The underlying hypothesis is that stenoses of haemodialysis access vessels or grafts cause vascular sound changes that are detectable using computerised data acquisition and analysis. Eleven patients participated in the study. Their vascular sounds were recorded before and after angiography, which was accompanied by angioplasty in most patients. The sounds were acquired using two electronic stethoscopes and then digitised and analysed on a personal computer. Vessel stenosis changes were found to be associated with changes in acoustic amplitude and/or spectral energy distribution. Certain acoustic parameters correlated well (correlation coefficient = 0.98, p < 0.0001) with the change in the degree of stenosis, suggesting that stenosis severity may be predictable from these parameters. Parameters also appeared to be sensitive to modest diameter changes (> 20%), (p < 0.005, Wilcoxon rank sum test). These results suggest that computerised analysis of vascular sounds may be useful in vessel patency surveillance. Further testing using longitudinal studies may be warranted.
authors.affiliation: Biomedical Acoustics Research Group, Department of Pediatrics, Rush Medical College, Chicago, USA. hmansy@rush.edu
authors.forename: H A
authors.initials: HA
authors.lastname: Mansy
authors.forename: S J
authors.initials: SJ
authors.lastname: Hoxie
authors.forename: N H
authors.initials: NH
authors.lastname: Patel
authors.forename: R H
authors.initials: RH
authors.lastname: Sandler
mesh_terms: D001166:Arteriovenous Shunt, Surgical; D001314:Auscultation / Q000379:methods*; D001807:Blood Vessel Prosthesis; D005260:Female; D006083:Graft Occlusion, Vascular / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D012815:Signal Processing, Computer-Assisted; D014654:Vascular Patency
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