Hemorrhagic stroke in a child with protein S and factor VII deficiencies.
A 12-year-old previously healthy male, with a family history of protein S deficiency, presented with confusion, aphasia, and right upper extremity weakness after a 10-day febrile illness. Imaging studies revealed sinovenous thrombosis and left parietal hemorrhagic stroke. On further investigation he was found to have both protein S and factor VII deficiencies.
Lietz
Katherine
K
Department of Pediatric Hematology/Oncology, Oklahoma University Health Sciences Center, and Children's Hospital, 940 NE Thirteenth Street, Oklahoma City, OK 73104, USA.
Kuehling
Stephanie E
SE
Parkhurst
Joan B
JB
D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D002648:Child; D005168:Factor VII Deficiency / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D018455:Protein S Deficiency / Q000150:complications* / Q000175:diagnosis; D011859:Radiography; D012851:Sinus Thrombosis, Intracranial / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology; D020521:Stroke / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology