The application of micro reactors for organic synthesis.
This tutorial review describes how micro reactors are being applied to synthetic chemistry covering a wide range of applications, from the preparation of nanograms of material for drug discovery and screening to the multi-tonne production of fine chemicals. This article explores how miniaturisation may revolutionise chemical synthesis and demonstrates that products are generated in higher yield and purity compared to the equivalent bulk reactions, in much shorter periods of time.
Watts
Paul
P
Department of Chemistry, University of Hull, Cottingham Road, Hull, UKHU6 7RX. P.Watts@hull.ac.uk
Haswell
Stephen J
SJ
D020650:Combinatorial Chemistry Techniques; D017076:Computer-Aided Design; D004151:Dipeptides / Q000138:chemical synthesis; D015195:Drug Design; D008904:Miniaturization; D015394:Molecular Structure; D009930:Organic Chemicals / Q000138:chemical synthesis*; D004364:Pharmaceutical Preparations; D013678:Technology, Pharmaceutical / Q000379:methods*
D004151:Dipeptides; D009930:Organic Chemicals; D004364:Pharmaceutical Preparations