title: Room temperature palladium catalysed coupling of acyl chlorides with terminal alkynes.
abstract: Conditions are reported for the facile, high-yielding coupling of acyl chlorides with terminal alkynes in a reaction involving palladium and copper iodide; the reaction is tolerant of a wide variety of acyl chlorides and terminal alkynes and provides a convenient one-pot route to acetylenic ketones.
authors.affiliation: School of Chemistry, University of Bristol, Cantock's Close, Bristol, UKBS8 1TS. r.j.cox@bris.ac.uk
authors.forename: Russell J
authors.initials: RJ
authors.lastname: Cox
authors.forename: Dougal J
authors.initials: DJ
authors.lastname: Ritson
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Dane
authors.forename: John
authors.initials: J
authors.lastname: Berge
authors.forename: Jonathan P H
authors.initials: JP
authors.lastname: Charmant
authors.forename: Anob
authors.initials: A
authors.lastname: Kantacha
mesh_terms: D000480:Alkynes / Q000737:chemistry* / Q000378:metabolism; D001565:Benzoates / Q000737:chemistry* / Q000378:metabolism; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007454:Iodides / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013696:Temperature
chemical_list: D000480:Alkynes; D001565:Benzoates; D007454:Iodides; D010165:Palladium; D003300:Copper; C073870:cuprous iodide; C013409:benzoyl chloride