Lipid rafts and their roles in T-cell activation.
Lipid rafts are defined as detergent-resistant membrane microdomains of specific lipid and protein composition. They are involved in many aspects of cell biology, including T-cell activation and immunoreceptor signaling. This review discusses current controversies around lipid rafts and summarizes recent developments in the area.
Horejsí
Václav
V
Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic. horejsi@biomed.cas.cz
D006801:Humans; D008213:Lymphocyte Activation / Q000502:physiology*; D021962:Membrane Microdomains / Q000737:chemistry / Q000502:physiology*; D011948:Receptors, Antigen, T-Cell / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology; D013601:T-Lymphocytes / Q000502:physiology*
D011948:Receptors, Antigen, T-Cell