title: Prognostic usefulness of white blood cell count and temperature in acute myocardial infarction (from the CARDINAL Trial).
abstract: White blood cell (WBC) count and temperature are 2 global measures of inflammation that are systematically gathered and easily identifiable in a clinical setting, unlike many other markers of inflammation being investigated in patients with coronary artery disease. The prognostic usefulness of the WBC count and temperature were evaluated in a large acute myocardial infarction trial, the Complement And ReDuction of INfarct size after Angioplasty or Lytics program. Baseline and serial measurements of WBC counts and temperature were correlated with infarct size and clinical outcome.
authors.affiliation: Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA.
authors.forename: Manesh R
authors.initials: MR
authors.lastname: Patel
authors.forename: Kenneth W
authors.initials: KW
authors.lastname: Mahaffey
authors.forename: Paul W
authors.initials: PW
authors.lastname: Armstrong
authors.forename: W Douglas
authors.initials: WD
authors.lastname: Weaver
authors.forename: Gudaye
authors.initials: G
authors.lastname: Tasissa
authors.forename: Judith S
authors.initials: JS
authors.lastname: Hochman
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Todaro
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Malloy
authors.forename: Scott
authors.initials: S
authors.lastname: Rollins
authors.forename: Pierre
authors.initials: P
authors.lastname: Theroux
authors.forename: Witold
authors.initials: W
authors.lastname: Ruzyllo
authors.forename: Jose C
authors.initials: JC
authors.lastname: Nicolau
authors.forename: Christopher B
authors.initials: CB
authors.lastname: Granger
mesh_terms: D017130:Angioplasty; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized; D019540:Area Under Curve; D001831:Body Temperature; D016009:Chi-Square Distribution; D003402:Creatine Kinase / Q000097:blood; D006801:Humans; D007958:Leukocyte Count; D016014:Linear Models; D009203:Myocardial Infarction / Q000276:immunology* / Q000401:mortality / Q000628:therapy; D011237:Predictive Value of Tests; D011379:Prognosis; D057127:Single-Chain Antibodies; D016019:Survival Analysis; D015912:Thrombolytic Therapy
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D057127:Single-Chain Antibodies; C402724:pexelizumab; D003402:Creatine Kinase