A novel chiral stationary phase derived from L-proline for liquid chromatographic resolution of chiral compounds.
The design and preparation of a novel chiral stationary phase (CSP) were described. The chiral resolutions of N-3,5-dinitrobenzoyl-DL-amino acid methyl esters were performed on the CSP. The selectivities were between 1.04 and 1.18. The applications of the CSP and the optimization of the chromatographic conditions will be further studied.
Zhou
H
H
Chengdu Institute of Organic Chemistry, the Chinese Academy of Sciences, Chengdu, 610041.
Long
Y
Y
Huang
T
T
D002853:Chromatography, Liquid / Q000295:instrumentation / Q000379:methods*; D011392:Proline / Q000031:analogs & derivatives / Q000737:chemistry*; D013237:Stereoisomerism
D011392:Proline