[Effect of omega-3 polyunsaturated fatty acids of animal origin on changes in regulation of lipid peroxidation in patients with ischemic heart disease].
The study's results showed reliable decrease in lipid peroxidation activity according to value of general sum of light, induced by hydrogen peroxide of initiated hemoluminescence and malonic dialdehyde concentration (P<0.05). The activity of antioxidant enzymes in the second group as compared with the control one has changed as follows: catalase concentration of blood serum of patients with ischemic heart disease increased by 59.49% (P<0.05), superoxide dismutase concentration--decreased by 28.64% (P<0.05). The above mentioned changes show, that the treatment with Tecom medication, which consist of omega-3 polyunsaturated fatty acids of animal origin does not stress peroxid antioxidant system, does not affect cell membrane stability, does not lead to progression of ischemic heart disease course.
Kyrylenko
O Ie
OIe
Kukoba
T V
TV
Moĭbenko
O O
OO
Nikula
T D
TD
D000368:Aged; D000818:Animals; D002374:Catalase / Q000378:metabolism; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000378:metabolism; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects*; D008054:Lipid Peroxides / Q000097:blood; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000188:drug therapy* / Q000201:enzymology / Q000378:metabolism; D013482:Superoxide Dismutase / Q000378:metabolism; D016896:Treatment Outcome
D015525:Fatty Acids, Omega-3; D008054:Lipid Peroxides; D002374:Catalase; D013482:Superoxide Dismutase