Biomechanical measures of neuromuscular control and valgus loading of the knee predict anterior cruciate ligament injury risk in female athletes: a prospective study.
BACKGROUND
Female athletes participating in high-risk sports suffer anterior cruciate ligament injury at a 4- to 6-fold greater rate than do male athletes.


OBJECTIVE
Prescreened female athletes with subsequent anterior cruciate ligament injury will demonstrate decreased neuromuscular control and increased valgus joint loading, predicting anterior cruciate ligament injury risk.


METHODS
Cohort study; Level of evidence, 2.


METHODS
There were 205 female athletes in the high-risk sports of soccer, basketball, and volleyball prospectively measured for neuromuscular control using 3-dimensional kinematics (joint angles) and joint loads using kinetics (joint moments) during a jump-landing task. Analysis of variance as well as linear and logistic regression were used to isolate predictors of risk in athletes who subsequently ruptured the anterior cruciate ligament.


RESULTS
Nine athletes had a confirmed anterior cruciate ligament rupture; these 9 had significantly different knee posture and loading compared to the 196 who did not have anterior cruciate ligament rupture. Knee abduction angle (P<.05) at landing was 8 degrees greater in anterior cruciate ligament-injured than in uninjured athletes. Anterior cruciate ligament-injured athletes had a 2.5 times greater knee abduction moment (P<.001) and 20% higher ground reaction force (P<.05), whereas stance time was 16% shorter; hence, increased motion, force, and moments occurred more quickly. Knee abduction moment predicted anterior cruciate ligament injury status with 73% specificity and 78% sensitivity; dynamic valgus measures showed a predictive r2 of 0.88.


CONCLUSIONS
Knee motion and knee loading during a landing task are predictors of anterior cruciate ligament injury risk in female athletes.


CONCLUSIONS
Female athletes with increased dynamic valgus and high abduction loads are at increased risk of anterior cruciate ligament injury. The methods developed may be used to monitor neuromuscular control of the knee joint and may help develop simpler measures of neuromuscular control that can be used to direct female athletes to more effective, targeted interventions.
Hewett
Timothy E
TE
Cincinnati Children's Hospital Research Foundation, Sports Medicine Biodynamics Center, Division of Molecular Cardiovascular Biology, Cincinatti Children's Hospital Medical Center, Cincinnati, OH 45229, USA. tim.hewett@chmcc.org
Myer
Gregory D
GD
Ford
Kevin R
KR
Heidt
Robert S
RS
Colosimo
Angelo J
AJ
McLean
Scott G
SG
van den Bogert
Antonie J
AJ
Paterno
Mark V
MV
Succop
Paul
P
D000293:Adolescent; D000070598:Anterior Cruciate Ligament Injuries; D001490:Basketball / Q000293:injuries*; D001696:Biomechanical Phenomena / Q000379:methods; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D007698:Kinesis; D007718:Knee Injuries / Q000209:etiology / Q000503:physiopathology; D007719:Knee Joint / Q000503:physiopathology; D012399:Rotation; D012421:Rupture / Q000209:etiology; D012737:Sex Factors; D012916:Soccer / Q000293:injuries*; D013647:Task Performance and Analysis; D016474:Weight-Bearing