Mannose-substituted PPEs detect lectins: a model for Ricin sensing.
The interaction of a mannose-substituted poly(para phenyleneethynylene) (mPPE) with a lectin, Concanavalin A (ConA), is reported; the ConA causes fluorescence quenching of the mPPE with a K(SV) of 5.6 x 10(5).
Kim
Ik-Bum
IB
School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta GA 30332, USA.
Wilson
James N
JN
Bunz
Uwe H F
UH
D000480:Alkynes / Q000138:chemical synthesis / Q000737:chemistry*; D003208:Concanavalin A / Q000737:chemistry; D004987:Ethers / Q000138:chemical synthesis / Q000737:chemistry*; D037102:Lectins / Q000737:chemistry*; D008358:Mannose / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry; D010165:Palladium / Q000737:chemistry; D010316:Particle Size; D012276:Ricin / Q000032:analysis / Q000737:chemistry*
D000480:Alkynes; D004987:Ethers; D037102:Lectins; D009942:Organometallic Compounds; C436384:phenyleneethynylene; D003208:Concanavalin A; D010165:Palladium; D012276:Ricin; D008358:Mannose