title: Quercetin alleviates activities of intestinal and renal disaccharidases in streptozotocin-induced diabetic rats.
abstract: Specific activities of both intestinal and renal dissacharidases, such as sucrase, maltase, and lactase, were altered in diabetic rats. Our study was focused to evaluate the effect of feeding quercetin - a bioflavanoid on intestinal and renal dissacharidases in streptozotocin-induced diabetic rats. The rats were fed with 0.1% quercetin in diet. A reduction in intestinal maltase and sucrase, activities in quercetin-fed diabetic rats was observed in contrast to the increased activities in the starch-fed diabetic rats. A significant amelioration in renal dissacharidase activities in quercetin-fed diabetic rats was observed when compared to decreased activity in starch-fed diabetic rats.
authors.affiliation: Department of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore, India.
authors.forename: Rashmi
authors.initials: R
authors.lastname: Ramachandra
authors.forename: Ajaya K
authors.initials: AK
authors.lastname: Shetty
authors.forename: Paramahans V
authors.initials: PV
authors.lastname: Salimath
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003921:Diabetes Mellitus, Experimental / Q000201:enzymology*; D004032:Diet; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004186:Disaccharidases / Q000378:metabolism*; D006029:Glycosuria / Q000652:urine; D007422:Intestines / Q000201:enzymology*; D007668:Kidney / Q000201:enzymology*; D043322:Lactase / Q000378:metabolism; D008297:Male; D011794:Quercetin / Q000008:administration & dosage*; D051381:Rats; D017208:Rats, Wistar; D013213:Starch / Q000008:administration & dosage; D013393:Sucrase / Q000378:metabolism; D000520:alpha-Glucosidases / Q000378:metabolism
chemical_list: D001786:Blood Glucose; D004040:Dietary Carbohydrates; D013213:Starch; D011794:Quercetin; D004186:Disaccharidases; D043322:Lactase; D000520:alpha-Glucosidases; D013393:Sucrase