title: [Screening for the G1528C mutation in long chain fatty acid oxidation enzyme in Han nationality in Beijing population].
abstract: OBJECTIVE
  To explore the carrier rate of G1528C mutation in alpha-subunit gene of MTP in Chinese newborns.
  
  
  METHODS
  1 200 cases of cord blood samples were taken in pregnant women with Han nationality in Chinese. PCR-RFLP analysis was conducted for detection of G1528C mutation.
  
  
  RESULTS
  No. G1528C mutations in LCHAD gene were found in these study subjects.
  
  
  CONCLUSIONS
  G1528C is probably not the common prevalent mutation in MTP gene in Chinese. Different prevalent mutation between Chinese and Western white people needs further study.
authors.affiliation: Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100083, China.
authors.forename: Jin-ming
authors.initials: JM
authors.lastname: Zhu
authors.forename: Zi
authors.initials: Z
authors.lastname: Yang
authors.forename: Mei
authors.initials: M
authors.lastname: Yu
authors.forename: Rong
authors.initials: R
authors.lastname: Wang
authors.forename: Rong-hua
authors.initials: RH
authors.lastname: Ye
authors.forename: Hui-xia
authors.initials: HX
authors.lastname: Yang
authors.forename: Gui-rong
authors.initials: GR
authors.lastname: Zhai
authors.forename: Qi
authors.initials: Q
authors.lastname: Wang
mesh_terms: D002681:China / Q000208:ethnology; D005260:Female; D005820:Genetic Testing; D006801:Humans; D007231:Infant, Newborn; D008052:Lipid Metabolism, Inborn Errors / Q000235:genetics; D008297:Male; D063991:Mitochondrial Trifunctional Protein; D009097:Multienzyme Complexes / Q000235:genetics*; D010084:Oxidation-Reduction; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D009097:Multienzyme Complexes; D063991:Mitochondrial Trifunctional Protein