title: Electron microscopic study of subcapsular cell hyperplasia in the adrenal glands of IQI/Jic mice.
abstract: Hyperplastic cells in subcapsular cell hyperplasia (SCH) lesion in adrenal glands of female IQI/Jic mice were examined by electron microscopy. These cells were small and polygonal, and had irregular nuclei, elongated mitochondria with lamellar cristae and dense lipid droplets. While these cells showed different features, some of them had desmosomes and basement membranes, and a few round mitochondria with tubular cristae as endocrine cells. These findings suggest that hyperplastic cells in SCH lesions might originate from endocrine blastemic cells.
authors.affiliation: National Institute of Industrial Health, Kawasaki, Japan.
authors.forename: Jong-Soo
authors.initials: JS
authors.lastname: Kim
authors.forename: Hisayo
authors.initials: H
authors.lastname: Kubota
authors.forename: Toshio
authors.initials: T
authors.lastname: Sakai
authors.forename: Kunio
authors.initials: K
authors.lastname: Doi
authors.forename: Junzo
authors.initials: J
authors.lastname: Saegusa
mesh_terms: D000311:Adrenal Glands / Q000166:cytology* / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D000818:Animals; D002467:Cell Nucleus / Q000473:pathology; D005260:Female; D006965:Hyperplasia; D050356:Lipid Metabolism; D051379:Mice; D008815:Mice, Inbred Strains; D008854:Microscopy, Electron; D008928:Mitochondria / Q000473:pathology