[Caveolae/caveolins and virus infection].
Caveolae, whose major structural proteins are Caveolins, are classically defined as flask-shaped plasma membrane invaginations with a characteristic diameter of 50 to 100 nm. Caveolae/Caveolins play important roles in many physiological and pathological activities. In recent years, Caveolae/Caveolins were found to associate with the absorption, entry, trafficking, replication, assembly and budding for many viruses. This route helps break a new pathway to the exploitation of new antiviral drugs and the prevention and treatment of tumors.
Luo
Di-Xian
DX
Institute of pharmacy and pharmacology, Nanhua University, Hengyang.
Yang
Hui-Ling
HL
Liao
Duan-Fang
DF
Wan
Yan-Ping
YP
D000818:Animals; D021941:Caveolae / Q000502:physiology*; D022461:Caveolins / Q000502:physiology*; D002462:Cell Membrane / Q000502:physiology; D004705:Endocytosis; D006801:Humans; D015398:Signal Transduction / Q000502:physiology; D013539:Simian virus 40 / Q000502:physiology; D014777:Virus Diseases / Q000821:virology*; D014780:Viruses / Q000254:growth & development
D022461:Caveolins