title: [Influence of blockades with local anesthetics on the stimulation ability of a nerve by peripheral nerve stimulation. Results of a randomized study].
abstract: In the present study we examined the influence of local anesthetics on the ability to stimulate a nerve by means of peripheral nerve stimulation. In 35 patients either 5 ml saline (group 1, n=18) or local anesthetics (group 2, n=17) were injected close to the sciatic nerve in a randomized and double-blind manner. The current needed to stimulate the nerve was measured 30 s and 2 min after injection. The results showed that 30 s and 2 min after injection of local anesthetics there is a strong local anesthetic effect. Therefore nerve damage might occur despite the use of peripheral nerve stimulation. Thus, the multiple injection technique in a close anatomical area has to be considered critically, because anesthetized or partially anesthetized nerves have a lower stimulating ability and could be damaged by a second or third puncture.
authors.affiliation: Abteilung für Anästhesie, BG Unfallklinik, Murnau.
authors.forename: M
authors.initials: M
authors.lastname: Neuburger
authors.forename: O
authors.initials: O
authors.lastname: Gültlinger
authors.forename: B
authors.initials: B
authors.lastname: Ass
authors.forename: J
authors.initials: J
authors.lastname: Büttner
authors.forename: H
authors.initials: H
authors.lastname: Kaiser
mesh_terms: D000779:Anesthetics, Local / Q000494:pharmacology*; D004311:Double-Blind Method; D004558:Electric Stimulation; D006801:Humans; D009407:Nerve Block; D010525:Peripheral Nerves / Q000187:drug effects*; D012584:Sciatic Nerve / Q000187:drug effects / Q000502:physiology
chemical_list: D000779:Anesthetics, Local
references.citation: Acta Anaesthesiol Scand. 1999 Apr;43(4):398-404
references.pmid: 10225072
references.citation: Anesthesiology. 2002 Nov;97(5):1274-80
references.pmid: 12411815
references.citation: Anesth Analg. 1999 Apr;88(4):847-52
references.pmid: 10195536
references.citation: Anesth Analg. 2001 Jul;93(1):183-6
references.pmid: 11429362
references.citation: Reg Anesth Pain Med. 1999 Nov-Dec;24(6):509-13
references.pmid: 10588553
references.citation: Anesthesiology. 1997 Sep;87(3):479-86
references.pmid: 9316950
references.citation: Reg Anesth Pain Med. 2002 Mar-Apr;27(2):227-8; discussion 228
references.pmid: 11915079
references.citation: Br J Anaesth. 2003 Oct;91(4):519-24
references.pmid: 14504153
references.citation: Anesth Analg. 2004 Oct;99(4):1225-30, table of contents
references.pmid: 15385381
references.citation: Reg Anesth Pain Med. 2004 May-Jun;29(3):185-8
references.pmid: 15138900
references.citation: Reg Anesth Pain Med. 2004 May-Jun;29(3):189-93
references.pmid: 15138901