title: [Repeated changes of electrocardiogram caused by Takotsubo-type cardiomyopathy: a case with hypertrophic nonobstructive cardiomyopathy].
abstract: A 67-year-old woman had been examined due to abnormalities on electrocardiography (ECG) at a medical checkup three years previously. When a negative T-wave was seen in leads I, aVL, and V1 to V4, but the abnormal findings were improved at consultation. Echocardiography revealed apical hypertrophy and hypertrophic nonobstructive cardiomyopathy was diagnosed. She felt chest discomfort in September, 2003 and an ECG showed a negative T-wave in leads I, II, III aVL, aVF and V2 to V6 and an elongation of QT interval Left ventriculography revealed myocardial hypertrophy at the left ventricular apex and left ventriclar wall motion was normal. Coronary angiography did not show any significant luminal narrowing. I-123 metaiodobenzyl-guanitidine scintigraphy showed marked perfusion defects at the left ventricular apex. After five months, ECG showed an improvement of the QT interval and a decrease in the negative T-wave. We considered that the repeated changes of ECG were caused by Takotsubo-type cardiomyopathy.
authors.affiliation: Second Department of Internal Medicine, Ehime University School of Medicine.
authors.forename: Seigo
authors.initials: S
authors.lastname: Miyoshi
authors.forename: Yuji
authors.initials: Y
authors.lastname: Hara
authors.forename: Akiyoshi
authors.initials: A
authors.lastname: Ogimoto
authors.forename: Yuji
authors.initials: Y
authors.lastname: Shigematsu
authors.forename: Takafumi
authors.initials: T
authors.lastname: Okura
authors.forename: Jitsuo
authors.initials: J
authors.lastname: Higaki
mesh_terms: D000368:Aged; D002312:Cardiomyopathy, Hypertrophic / Q000503:physiopathology*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D009200:Myocardial Contraction; D017682:Myocardial Stunning / Q000503:physiopathology*; D012008:Recurrence