title: Pure gastric yolk sac tumor that was diagnosed after curative resection: case report and review of literature.
abstract: We recently experienced an 87-yr-old man with gastric yolk sac tumor. Preoperative diagnosis was poorly differentiated adenocarcinoma in the cardia of stomach without apparent metastasis. A total gastrectomy was performed. The precise histological examination after surgery revealed the tumor was composed of pure gastric yolk sac tumor without adenocarcinomatous components. The surgical margin and the resected lymph nodes were histologically negative for the tumor and a curative resection was performed. Five months after the operation, enlargement of the intraabdominal lymph nodes occurred with elevation of serum alpha fetoprotein (AFP), and the patient died 2 mo later. Gastric yolk sac tumors are very rare, and only six cases of gastric yolk sac tumors have been previously reported in the literature. Five out of six cases are accompanied by components of adenocarcinoma, and our present case is the second report of pure gastric yolk sac tumor to the best of our knowledge.
authors.affiliation: Digestive Disease Center, Kyoto Katsura Hospital, 17 Yamada Hirao-cho, Nishikyo-ku, Kyoto, 615-8256, Japan. kanai@kuhp.kyoto-u.ac.jp
authors.forename: Masashi
authors.initials: M
authors.lastname: Kanai
authors.forename: Ayao
authors.initials: A
authors.lastname: Torii
authors.forename: Akihiko
authors.initials: A
authors.lastname: Hamada
authors.forename: Yoko
authors.initials: Y
authors.lastname: Endo
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Takeda
authors.forename: Masashi
authors.initials: M
authors.lastname: Yamakawa
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hikita
authors.forename: Haruhiro
authors.initials: H
authors.lastname: Nishikawa
authors.forename: Jiro
authors.initials: J
authors.lastname: Ochi
authors.forename: Kensuke
authors.initials: K
authors.lastname: Miura
authors.forename: Masashi
authors.initials: M
authors.lastname: Noguchi
authors.forename: Ippei
authors.initials: I
authors.lastname: Kashu
authors.forename: Takaki
authors.initials: T
authors.lastname: Sakurai
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D000368:Aged; D000369:Aged, 80 and over; D018240:Endodermal Sinus Tumor / Q000473:pathology* / Q000601:surgery*; D017809:Fatal Outcome; D005743:Gastrectomy; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery*
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