[Studies on dissolution rate in vitro of silymarin dropping pill].
OBJECTIVE
To test the dissolution rate of silymarin dropping pill as well as to be compared with other three commercial products of the silymarin.


METHODS
By UV spectrophotometry, we studied the dissolution conditions of silymarin dropping pill and compared its dissolution rate with Yiganling tablets (film-coating, sugar-coating) and Legalon capsule which are available in the market.


RESULTS
The dissolution parameters T50 and Td of silymarin dropping pill, Yiganling tablet (film-coating), Yiganling tablet (sugar-coating) and Legalon capsule are 6.78, 9.85 min, 51.01, 73.78 min, 74.35, 86.97 min and 53.10, 72.65 min.


CONCLUSIONS
The dissolution rate of silymarin dropping pill is superior to that of two kinds of Yiganling tablets and Legalon capsule.
Sun
Xia
X
Shanghai Jiao Tong University, Shanghai 200030, China.
Qiu
Ming-feng
MF
Li
Shao-shun
SS
Wang
Jian-xin
JX
Shen
Qi
Q
Jia
Wei
W
D002214:Capsules; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000737:chemistry*; D012838:Silymarin / Q000008:administration & dosage / Q000737:chemistry*; D012995:Solubility; D013056:Spectrophotometry, Ultraviolet; D013607:Tablets
D002214:Capsules; D004365:Drugs, Chinese Herbal; D012838:Silymarin; D013607:Tablets