title: [The influence of chloroquine on some biochemical and hematological parameters in patients with critical limb ischemia].
abstract: CLI represents a major medical and social problem. The incidence is increasing and currently it was estimated 500-1000 per 1 million inhabitants. We carried out a clinical study (2000-2004) concerning monitoring of some hematological and biochemical markers during reperfusion in patients with CLI. The subject of our interest included possibilities to influence PMNL elastase by medical means and neutrophil-lymphocyte ratio which is considered a reliable and simple parameter to assess severity of clinical conditions.
authors.affiliation: Klinika cievnej chirurgie, Slovensý ústav srdcových a cievnych chorôb, Bratislava, Slovenská republika. mondo@pobox.sk
authors.forename: P
authors.initials: P
authors.lastname: Mondek
authors.forename: R
authors.initials: R
authors.lastname: Slysko
authors.forename: V
authors.initials: V
authors.lastname: Sefránek
authors.forename: I
authors.initials: I
authors.lastname: Pechán
mesh_terms: D002738:Chloroquine / Q000627:therapeutic use*; D006801:Humans; D007511:Ischemia / Q000188:drug therapy* / Q000378:metabolism; D007866:Leg / Q000098:blood supply*
chemical_list: D002738:Chloroquine