[Studies on purification of the extract of fructus Gardeniae for injection by macroreticular resins].
OBJECTIVE
To purify the extract of fructus gardeniae for injection by macroreticular resins in purification process of traditional Chinese medicine (TCM) Injections.


METHODS
Using fructus gardeniae as sample, on base of obtaining the extract by employing macroreticular resin, quality evaluation and rationality of purification methods had been studied by the quantitative analysis of active ingredients and the characteristics of micromeritics, safety and stability of the extract.


RESULTS
The experiment showed the extract of fructus gardeniae for injection had been produced successfully by macroreticular resin.


CONCLUSIONS
Using macroreticular resins is a promising purification way of TCM injections, whereas a more consummate method of quality evaluation must be established to ensure safety, efficiency and stability of the preparation in the process.
Chen
Gang
G
Huaxi School of Pharmacy, Sichuan University, Chengdu 610041, China.
Hou
Shi-xiang
SX
Ye
Li-min
LM
Hu
Ping
P
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000302:isolation & purification* / Q000633:toxicity; D005638:Fruit / Q000737:chemistry; D032062:Gardenia / Q000737:chemistry*; D007267:Injections; D039823:Iridoids / Q000302:isolation & purification; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry*; D011714:Pyrans / Q000302:isolation & purification; D011786:Quality Control; D012117:Resins, Synthetic; D013678:Technology, Pharmaceutical / Q000379:methods*
D004365:Drugs, Chinese Herbal; D039823:Iridoids; D011714:Pyrans; D012117:Resins, Synthetic; C056587:gardenoside