title: Pattern of glucose hypometabolism in frontotemporal dementia with motor neuron disease.
abstract: Frontotemporal dementia (FTD) often coexists with motor neuron disease (MND). To characterize glucose hypometabolism in patients with FTD with MND (FTD/MND), the authors compared the glucose metabolism of 8 patients with FTD/MND with that of 29 patients with FTD. All of the patients with FTD/MND showed glucose hypometabolism only in the frontal area, whereas most patients with FTD had hypometabolism in the frontal and temporal areas. FTD/MND also showed a more symmetric pattern of glucose hypometabolism than FTD.
authors.affiliation: Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Y
authors.initials: Y
authors.lastname: Jeong
authors.forename: K C
authors.initials: KC
authors.lastname: Park
authors.forename: S S
authors.initials: SS
authors.lastname: Cho
authors.forename: E J
authors.initials: EJ
authors.lastname: Kim
authors.forename: S J
authors.initials: SJ
authors.lastname: Kang
authors.forename: S E
authors.initials: SE
authors.lastname: Kim
authors.forename: E
authors.initials: E
authors.lastname: Kang
authors.forename: D L
authors.initials: DL
authors.lastname: Na
mesh_terms: D000368:Aged; D010244:Bulbar Palsy, Progressive / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism; D002531:Cerebellum / Q000000981:diagnostic imaging / Q000378:metabolism*; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000378:metabolism; D003704:Dementia / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism*; D004292:Dominance, Cerebral; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016472:Motor Neuron Disease / Q000150:complications / Q000378:metabolism*; D009928:Organ Specificity; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D013702:Temporal Lobe / Q000000981:diagnostic imaging / Q000378:metabolism*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D005947:Glucose