title: [Radiation therapy for prostate cancer].
abstract: The advent of image-guided or CT-based treatment planning, such as 3D-conformal or intensity modulated radiation therapy has allowed safe delivery of high- dose radiation therapy in men with prostate cancer with an acceptable rate of side effects and complications. External-beam radiation therapy designed to decrease exposure of normal tissues using methods such as 3D-conformal treatment planning is under clinical evaluation. Randomized trial shows escalation of radiation dose leads to improved biochemical disease-free survival for a select group of patients. Interstitial brachytherapy has been also employed for patients with selected for favorable characteristics, including low Gleason score, low PSA level, and stage T1 to T2 tumors. Long-term follow-up of patients is necessary to assess treatment efficacy and side effects.
authors.affiliation: Division of Radiation Oncology, National Cancer Center Hospital.
authors.forename: Minako
authors.initials: M
authors.lastname: Sumi
mesh_terms: D001918:Brachytherapy / Q000379:methods; D002986:Clinical Trials as Topic; D005500:Follow-Up Studies; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D009367:Neoplasm Staging; D018579:Patient Selection; D011471:Prostatic Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods; D020266:Radiotherapy, Conformal / Q000379:methods; D011882:Radiotherapy, High-Energy / Q000379:methods; D013997:Time Factors
chemical_list: D007457:Iodine Radioisotopes