title: Design, synthesis and antimalarial activity of trifluoromethylartemisinin-mefloquine dual molecules.
authors.affiliation: CNRS-BIOCIS, Faculté de Pharmacie, 92296 Châtenay-Malabry, France.
authors.forename: Fabienne
authors.initials: F
authors.lastname: Grellepois
authors.forename: Philippe
authors.initials: P
authors.lastname: Grellier
authors.forename: Danièle
authors.initials: D
authors.lastname: Bonnet-Delpon
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Bégué
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000138:chemical synthesis* / Q000494:pharmacology / Q000627:therapeutic use; D037621:Artemisinins / Q000737:chemistry*; D015195:Drug Design; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D008288:Malaria / Q000188:drug therapy; D015767:Mefloquine / Q000031:analogs & derivatives* / Q000737:chemistry; D051379:Mice; D015394:Molecular Structure; D018512:Parasitemia / Q000188:drug therapy; D010962:Plasmodium berghei / Q000187:drug effects; D010963:Plasmodium falciparum / Q000187:drug effects
chemical_list: D000962:Antimalarials; D037621:Artemisinins; D006846:Hydrocarbons, Halogenated; D015767:Mefloquine