The effect of weight loss on a stable biomarker of inflammation, C-reactive protein.
Inflammation is pivotal in all phases of atherosclerosis. Increasing body weight is positively associated with inflammation. Weight loss studies have shown that decreasing body weight significantly decreases C-reactive protein, the prototypic biomarker for inflammation. Reducing inflammation through weight loss could therefore be associated with reduced risk for cardiovascular disease and other obesity-associated chronic diseases.
Dietrich
Marion
M
School of Public Health, University of California, Berkeley, CA, USA.
Jialal
Ishwarlal
I
D015415:Biomarkers / Q000378:metabolism; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000378:metabolism*; D003324:Coronary Artery Disease / Q000378:metabolism*; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D015850:Interleukin-6 / Q000097:blood; D009765:Obesity / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism; D015431:Weight Loss
D015415:Biomarkers; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D002097:C-Reactive Protein