title: The Doppler-derived myocardial performance index is determined by both left ventricular systolic and diastolic function as well as by afterload and left ventricular mass.
abstract: OBJECTIVE
  To investigate if the newly developed Doppler-derived myocardial performance index (MPI, also denoted TEI-index) is associated with variables reflecting both left ventricular (LV) systolic and diastolic function, as well as variables reflecting preload, afterload, and LV geometry.
  
  
  METHODS
  An echocardiographic examination including Doppler was carried out in 446 men aged 70 in a population-based survey (the ULSAM-study, Uppsala Longitudinal Study of Adult Men).
  
  
  RESULTS
  In multiple regression analysis, MPI was independently associated with ejection fraction (P < 0.001), E/A ratio (P < 0.001), total peripheral resistance index (P < 0.001), stroke volume to pulse pressure ratio (P < 0.02), stroke index (P < 0.01), and LV mass (P < 0.04), but not with heart rate or blood pressure.
  
  
  CONCLUSIONS
  The echocardiographically determined myocardial performance index is determined by both LV systolic and diastolic function as well as by afterload and left ventricular mass.
authors.affiliation: Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
authors.forename: Lars
authors.initials: L
authors.lastname: Lind
authors.forename: Bertil
authors.initials: B
authors.lastname: Andrén
authors.forename: Johan
authors.initials: J
authors.lastname: Arnlöv
mesh_terms: D000368:Aged; D001794:Blood Pressure / Q000502:physiology; D001830:Body Surface Area; D002302:Cardiac Output / Q000502:physiology; D015331:Cohort Studies; D003971:Diastole; D015150:Echocardiography, Doppler; D004562:Electrocardiography; D006339:Heart Rate / Q000502:physiology; D006352:Heart Ventricles / Q000033:anatomy & histology*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009200:Myocardial Contraction / Q000502:physiology*; D011159:Population Surveillance; D013318:Stroke Volume / Q000502:physiology; D013599:Systole; D014655:Vascular Resistance / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*