title: New parameters for left ventricular function in atrial fibrillation: based on the relationship between RR interval and performance.
abstract: This study was designed to obtain new parameters representing left ventricular (LV) function independent of irregular RR intervals in atrial fibrillation (AF). AF patients were divided into Normal (n=9) and LV Dysfunction (n=9) groups. The relations between LV outflow peak ejection velocity (Vpe) and preceding (RR-1) or prepreceding RR intervals (RR-2) were obtained using logarithmic equations, from which the squared correlation coefficient (r2), slope, Vpe at RR-1 or RR-2=1 sec (Vpe-1), and the ratio of slope to Vpe-1 (Slope/Vpe-1) were calculated. Among the parameters between RR-1 and Vpe, Slope/Vpe-1 was higher in LV Dysfunction group than in Normal group (p=0.05). When only coordinates with RR-1 from 0.6 to 1 sec were included, Slope/Vpe-1 (p=0.001) was higher in LV Dysfunction group than in Normal group. Among the parameters between RR-2 and Vpe, Slope/Vpe-1, slope, and r2 were different between the two groups. In multivariate analysis, Slope/Vpe-1 between RR-2 and Vpe was only independent parameter. However, Slope/Vpe-1 between RR-1 and Vpe in the coordinates with RR-1 from 0.6 to 1 sec had the highest discriminating power. New parameters derived from the relations between RR intervals and LV performance might be useful to evaluate LV function quantitatively in AF.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea.
authors.forename: Hong Sook
authors.initials: HS
authors.lastname: Ko
authors.forename: Chee Jeong
authors.initials: CJ
authors.lastname: Kim
authors.forename: Wang Seong
authors.initials: WS
authors.lastname: Ryu
mesh_terms: D000367:Age Factors; D000368:Aged; D001281:Atrial Fibrillation / Q000378:metabolism*; D016279:Atrial Function, Left; D004452:Echocardiography; D018619:Echocardiography, Doppler, Pulsed; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000502:physiology; D006352:Heart Ventricles; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D015999:Multivariate Analysis; D009200:Myocardial Contraction; D009206:Myocardium / Q000473:pathology; D013997:Time Factors; D016277:Ventricular Function, Left
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