title: Quantitative analysis of enalapril by 1H NMR spectroscopy in tablets.
abstract: A simple, rapid, accurate and selective 1H NMR method was developed for quantitative determination of enalapril maleate in pharmaceutical preparations. Spectra were determined in D2O, using L-leucine as internal standard. Both synthetic mixtures and commercial dosage forms were assayed, and the results were compared to those obtained using the USP XXIV procedure and were both in close agreement.
authors.affiliation: Departamento de Farmacia, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Ciudad Universitaria, 5000 Córdoba, Argentina.
authors.forename: Ariana
authors.initials: A
authors.lastname: Zoppi
authors.forename: Marcela
authors.initials: M
authors.lastname: Linares
authors.forename: Marcela
authors.initials: M
authors.lastname: Longhi
mesh_terms: D004656:Enalapril / Q000032:analysis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods* / Q000592:standards; D011522:Protons; D013607:Tablets
chemical_list: D011522:Protons; D013607:Tablets; D004656:Enalapril