Transtaganolides A-D: novel metabolites from Thapsia transtagana.
Four novel and unusual C-19 compounds from Thapsia transtagana, named transtaganolides A-D, have been isolated. Their structures were established by physical methods, including X-ray analysis of transtaganolides A and B. This is the first time that a 7-methoxy-4,5-dihydro-3H-oxepin-2-one ring has been found in a natural product. [structure: see text]
Saouf
Abderrahmane
A
Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, Apartado 40, 11510 Puerto Real, Cádiz, Spain.
Guerra
Francisco M
FM
Rubal
Juan J
JJ
Moreno-Dorado
F Javier
FJ
Akssira
Mohamed
M
Mellouki
Fouad
F
López
Matías
M
Pujadas
Antonio J
AJ
Jorge
Zacarías D
ZD
Massanet
Guillermo M
GM
D019661:Apiaceae / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004452:Echocardiography; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry* / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*
D006576:Heterocyclic Compounds, 4 or More Rings