The relationship between the systemic inflammatory response and survival in patients with transitional cell carcinoma of the urinary bladder.
The relationship between tumour stage, grade, elevated C-reactive protein concentration (<10/>10 mg l(-1)), adjuvant therapy and survival was examined in patients with biopsy proven bladder cancer (n=105). On multivariate analysis stage (HR 3.37, 95% CI 1.37-8.29, P=0.008), grade (HR 2.01, 95% CI 1.14-3.57, P=0.017) and preoperative C-reactive protein (HR 3.31, 95% CI 1.09-10.09, P=0.035) were independently associated with cancer-specific survival.
Hilmy
M
M
University Department of Surgery, Royal Infirmary, Glasgow G31 2ER, Scotland, UK. m.hilmy@doctors.net.uk
Bartlett
J M S
JM
Underwood
M A
MA
McMillan
D C
DC
D000368:Aged; D000704:Analysis of Variance; D002097:C-Reactive Protein / Q000378:metabolism; D002295:Carcinoma, Transitional Cell / Q000097:blood / Q000150:complications* / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D016001:Confidence Intervals; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D016019:Survival Analysis; D018746:Systemic Inflammatory Response Syndrome / Q000097:blood / Q000150:complications* / Q000401:mortality*; D001749:Urinary Bladder Neoplasms / Q000097:blood / Q000150:complications* / Q000401:mortality* / Q000473:pathology / Q000628:therapy
D002097:C-Reactive Protein
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