Optical coherence tomography in Best's disease: an observational case report.
OBJECTIVE
To report the optical coherence tomographic (OCT) findings in a case of Best's disease.


METHODS
Observational case report.


METHODS
Optical coherence tomography was carried out to understand the pathogenesis of Best's disease in a 13-year-old girl.


RESULTS
Optical coherence tomography demonstrated that the lipofuscin accumulated in a cystic space underneath the retinal pigment epithelium in the "pseudohypopyon stage" of Best's disease. It also demonstrated the disruption of the photoreceptors in the "scrambled egg" stage.


CONCLUSIONS
These new OCT findings could explain the retention of good visual acuity in the "pseudohypopyon stage" and the loss of visual acuity in the "scrambled egg" stage of Best's disease.
Vedantham
Vasumathy
V
Retina-Vitreous Service, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai 625 020, Tamilnadu, India. drvasumathy@yahoo.com
Ramasamy
Kim
K
D000293:Adolescent; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D008062:Lipofuscin / Q000378:metabolism; D008268:Macular Degeneration / Q000175:diagnosis* / Q000378:metabolism; D010857:Pigment Epithelium of Eye / Q000378:metabolism / Q000473:pathology; D012160:Retina / Q000378:metabolism / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods*
D008062:Lipofuscin