[Effectiveness of a modified Madde-type mastectomy in patients with breast cancer of I-II stage].
Effectiveness of mastectomy with two breast muscles preserved and total lymphdissection (Malden surgical operation) in I-II stage breast cancer patients has been studied. The control group has been operated using classical mastectomy after Golsted and its modified variant named after Peity. The degree of the disease dissemination was confirmed pathohistologicaly based on the 5-th edition of TNM system. It was established that the 5 year survival period among patients with primary tumor size getting pT1-2 doesn't depend on a volume of a surgical operation but correlates with the number of regional lymph nodes metastasis (pN1). It has totaled 85.3-87.2 % among pT1 pNO MO breast cancer patients, 73.5%--pT2 pNo MO, 63.7-69.3%--pT1-2pN1Mo. 81% of patients who had 1-3 regional lymph nodes metastasis is still alive after the 5 year survival period--57.2%, of those who had 4-9 regional metastasis overpassed this 5 year survival period and 10 or over regional metastasis survive only about 19%.
Savran
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D001365:Axilla; D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018270:Carcinoma, Ductal, Breast / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018275:Carcinoma, Lobular / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology / Q000601:surgery*; D015411:Mastectomy, Modified Radical / Q000379:methods*; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging