Delayed persistent estrus induced by continuous lighting after inadequate acclimation in rats.
While the normal estrous cycle of adequately acclimated female rats was replaced by a persistent estrus (PE) under continuous lighting, the onset of PE was delayed following several irregular cycles without acclimation or after acclimation for one week, suggesting that transportation induces a significant critical stress.
Furudate
Sen-ichi
S
Department of Laboratory Animal Science, Kitasato University School of Medicine, Sagamihara, Japan.
Takahashi
Akira
A
Takagi
Mamoru
M
Kuwada
Masahiro
M
D000064:Acclimatization / Q000502:physiology*; D000818:Animals; D000830:Animals, Laboratory / Q000502:physiology*; D030762:Estrous Cycle / Q000528:radiation effects; D005260:Female; D008029:Lighting / Q000009:adverse effects*; D051381:Rats; D017208:Rats, Wistar / Q000502:physiology*; D013312:Stress, Physiological / Q000503:physiopathology; D013997:Time Factors; D014186:Transportation