[Morphologic effect of finoptin and obzidane on intact ventricular cardiac myocytes].
Finoptin and obzidane influence on morphologic signs of intact ventricular cardiac hystiocytes has been examined during the experiments on animals by means of the complex of histological and histochemical methods, electron microscopy as well as morphometry. It has been established that long-term using of finoptin and obzidane medication to intact animals does not affect cardiac hystiocytes. Finoptin can increase the thickness of the glycocalix layer and partly block Ca2+ -binding locus of plasmolemma. Obzidane introduction enables to ensure constant energy-efficient, plastic and membrane-stabilizing effect. The medications use resulted in forming favorable initial conditions for increase in myocardium resistance to coronary insufficiency.
Verbyts'kyĭ
V V
VV
Shul'ts
N V
NV
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000818:Animals; D002121:Calcium Channel Blockers / Q000494:pharmacology*; D002462:Cell Membrane / Q000187:drug effects / Q000648:ultrastructure; D006352:Heart Ventricles / Q000187:drug effects / Q000648:ultrastructure*; D008854:Microscopy, Electron; D032383:Myocytes, Cardiac / Q000187:drug effects / Q000648:ultrastructure*; D011433:Propranolol / Q000494:pharmacology*; D011817:Rabbits; D014700:Verapamil / Q000494:pharmacology*
D000319:Adrenergic beta-Antagonists; D002121:Calcium Channel Blockers; D011433:Propranolol; D014700:Verapamil