[Progress in porky genes and transcriptome and discussion of relative issues].
To date, research on molecular base of porky molecular development was mainly involved in muscle growth and meat quality. Some functional genes including Hal gene and RN gene and some QTLs controlling or associated with porky growth and quality were detected through candidate gene approach and genome-wide scanning. Genic transcriptome pertinent to porcine muscle and adipose also came into study. At the same time, these researches have befallen some shortcomings to some extent. Research from molecular quantitative genetics showed shortcomings that single gene was devilishly emphasized and co-expression pattern of multi-genes was ignored. Research applying transcriptome analysis tool also met two of limitations, one was the singleness of type of molecular experimental techniques, and another was that genes of muscle and adipose were artificially divided into unattached two parts. Thus, porky genes were explored by parallel genetics based on systemic views and techniques to specially reveal the interactional mechanism of porky genes respectively controlling muscle and adipose, which would be important issues of genes and genome researches on porky development in the near future.
Zhu
Meng-Jin
MJ
Laboratory of Molecular Biology and Animal Breeding, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. zhumengjin@mail.hzau.edu.cn
Liu
Bang
B
Li
Kui
K
D000818:Animals; D020869:Gene Expression Profiling; D008460:Meat; D040641:Quantitative Trait Loci; D013552:Swine / Q000235:genetics*; D014158:Transcription, Genetic