title: Albumin-conjugated corrole metal complexes: extremely simple yet very efficient biomimetic oxidation systems.
abstract: An extremely simple biomimetic oxidation system, consisting of mixing metal complexes of amphiphilic corroles with serum albumins, utilizes hydrogen peroxide for asymmetric sulfoxidation in up to 74% ee. The albumin-conjugated manganese corroles also display catalase-like activity, and mechanistic evidence points toward oxidant-coordinated manganese(III) as the prime reaction intermediate.
authors.affiliation: Department of Chemistry and Institute of Catalysis Science and Technology, Technion-Israel Institute of Technology, Haifa 32000, Israel.
authors.forename: Atif
authors.initials: A
authors.lastname: Mahammed
authors.forename: Zeev
authors.initials: Z
authors.lastname: Gross
mesh_terms: D000818:Animals; D040761:Biomimetic Materials / Q000737:chemistry; D002374:Catalase / Q000737:chemistry; D006801:Humans; D006861:Hydrogen Peroxide / Q000737:chemistry; D058085:Iron Compounds / Q000737:chemistry; D008345:Manganese / Q000737:chemistry*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D011166:Porphyrins / Q000737:chemistry*; D012709:Serum Albumin / Q000737:chemistry*; D012756:Sheep; D013552:Swine
chemical_list: D058085:Iron Compounds; D011166:Porphyrins; D012709:Serum Albumin; C431863:corrole; D008345:Manganese; D006861:Hydrogen Peroxide; D002374:Catalase; D010100:Oxygen