title: [Effects of distress and coping on quality of life in HIV-positive patients: results of a longitudinal study].
abstract: Preserving health-related quality of life (QOL) is an important approach with HIV-positive patients. In a longitudinal study over 3 years, with three measurements each 18 months, we examined 56 of these patients for the influence of distress and coping (assessed by interviews) on physical, cognitive-emotional, and social QOL (using the SEL questionnaire). The patients were 32.9 years old on average, with 28.3 months since diagnosis. Seventy percent were male, 82% asymptomatic, 14% with ARC, and 4% with AIDS. Forty-five percent had been infected by homosexual intercourse, 14% by heterosexual intercourse, and 41% by iv drug abuse. The patients reported significantly worse physical and cognitive-emotional QOL than healthy subjects. Those HIV-positive persons with great distress showed significantly lower QOL scores. Multiple analyses of regression showed evasive-regressive coping at the T1, T2, and T3 levels as negative predictors, vs active, problem-focused coping as a positive predictor for nearly all QOL parameters at T3. HIV-positive patients with ARC or AIDS reported more physical complaints and lower physical QOL than asymptomatic persons. Physicians should suggest psychosocial support to patients with poor QOL scores.
authors.affiliation: Schwerpunkt Psychosomatik an der Klinik und Poliklinik für Innere Medizin II am Klinikum der Universität Regensburg, Deutschland. peter.leiberich@klinik.uni-regensburg.de
authors.forename: P
authors.initials: P
authors.lastname: Leiberich
authors.forename: M
authors.initials: M
authors.lastname: Brieger
authors.forename: K
authors.initials: K
authors.lastname: Schumacher
authors.forename: P
authors.initials: P
authors.lastname: Joraschky
authors.forename: E
authors.initials: E
authors.lastname: Olbrich
authors.forename: H
authors.initials: H
authors.lastname: Loew
authors.forename: K
authors.initials: K
authors.lastname: Tritt
mesh_terms: D000223:Adaptation, Psychological / Q000145:classification*; D000328:Adult; D015897:Comorbidity; D005260:Female; D005858:Germany / Q000453:epidemiology; D015658:HIV Infections / Q000175:diagnosis* / Q000453:epidemiology* / Q000523:psychology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011788:Quality of Life; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D012959:Socioeconomic Factors; D013315:Stress, Psychological / Q000175:diagnosis* / Q000453:epidemiology* / Q000523:psychology; D011795:Surveys and Questionnaires
references.citation: Clin Nurs Res. 1993 Aug;2(3):243-4
references.pmid: 8401239
references.citation: Qual Life Res. 1997 Aug;6(6):494-506
references.pmid: 9330550
references.citation: Eur J Epidemiol. 1996 Jun;12(3):221-8
references.pmid: 8884187
references.citation: Gen Hosp Psychiatry. 1986 Nov;8(6):395-403
references.pmid: 3792828
references.citation: J Adv Nurs. 2000 Nov;32(5):1213-23
references.pmid: 11115007
references.citation: HIV Clin Trials. 2002 May-Jun;3(3):202-18
references.pmid: 12032879
references.citation: AIDS Care. 1996 Feb;8(1):15-31
references.pmid: 8664366
references.citation: AIDS Patient Care STDS. 2002 Feb;16(2):83-96
references.pmid: 11874640
references.citation: Med Care. 1995 Apr;33(4 Suppl):AS173-82
references.pmid: 7723445
references.citation: Int J STD AIDS. 1999 Jun;10(6):383-91
references.pmid: 10414881
references.citation: J Adv Nurs. 1999 Jan;29(1):178-87
references.pmid: 10064297
references.citation: Clin Infect Dis. 1998 Jan;26(1):20-6
references.pmid: 9455505
references.citation: Psychother Psychosom Med Psychol. 2002 Mar-Apr;52(3-4):141-50
references.pmid: 11941521
references.citation: Qual Life Res. 1997 Aug;6(6):515-30
references.pmid: 9330552
references.citation: Med Care. 1998 Feb;36(2):138-54
references.pmid: 9475469
references.citation: Qual Life Res. 1997 Jan;6(1):3-10
references.pmid: 9062436
references.citation: J Consult Clin Psychol. 1992 Jun;60(3):463-9
references.pmid: 1619100
references.citation: J Acquir Immune Defic Syndr. 2002 Aug 15;30(5):485-92
references.pmid: 12154339
references.citation: Int J STD AIDS. 2001 Aug;12(8):505-12
references.pmid: 11487390
references.citation: J Assoc Nurses AIDS Care. 1997 Sep-Oct;8(5):21-30
references.pmid: 9298467
references.citation: Annu Rev Psychol. 2001;52:555-80
references.pmid: 11148317
references.citation: AIDS Care. 1999 Feb;11(1):71-86
references.pmid: 10434984
references.citation: Patient Educ Couns. 1994 Dec;24(3):217-35
references.pmid: 7753716
references.citation: AIDS Care. 2002 Dec;14(6):851-7
references.pmid: 12511217
references.citation: AIDS. 2002 Aug 16;16(12):1617-26
references.pmid: 12172083
references.citation: Qual Life Res. 1997 Aug;6(6):507-14
references.pmid: 9330551
references.citation: HIV Clin Trials. 2001 Nov-Dec;2(6):484-92
references.pmid: 11742437
references.citation: J Adv Nurs. 1999 Sep;30(3):597-605
references.pmid: 10499216
references.citation: Ann Intern Med. 2001 May 1;134(9 Pt 2):854-60
references.pmid: 11346321