Nasal potential difference increases with gestation in moderately preterm neonates on the first postnatal day.
At birth the mammalian airway switches from liquid secretion to absorption, an important mechanism in lung liquid clearance. Airway ion transport was examined on the first postnatal day in 38 moderately preterm infants (29-36 weeks gestation). The absorptive airway ion transport capacity was well developed regardless of respiratory condition and there was little capacity for Cl- secretion.
Gaillard
E A
EA
Liverpool Women's Hospital, Neonatal Unit, Liverpool, UK. gaillard@liv.ac.uk.
Shaw
N J
NJ
Wallace
H L
HL
Subhedar
N V
NV
Southern
K W
KW
D000042:Absorption; D001692:Biological Transport; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D008564:Membrane Potentials / Q000502:physiology; D012044:Regression Analysis; D012121:Respiration, Artificial; D012127:Respiratory Distress Syndrome, Newborn / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism* / Q000493:pharmacokinetics; D015222:Sodium Channels / Q000378:metabolism*
D015222:Sodium Channels; D012964:Sodium