Incorporating new imaging models in breast cancer management.
Mammography is the only screening test proven to decrease breast cancer morbidity and mortality. Although mammography is an effective screening tool, it does have limitations, particularly in women with dense breasts. New imaging techniques are emerging to overcome these limitations and enhance cancer detection, improving patient outcome. Digital mammography, computer aided detection, breast ultrasound and breast magnetic resonance imaging (MRI) are frequently used adjuncts to mammography in today's clinical practice. Recent studies have shown that these techniques can enhance the radiologist's ability to detect cancer and assess disease extent, which is crucial in treatment planning and staging. Positron emission tomography (PET) also plays an important role in staging breast cancer and monitoring treatment response. Other modalities such as tomosynthesis and MR lymphangiography show promise in overcoming the problems related to dense breast tissue and the lack of noninvasive methods to assess lymph node status. Imaging-guided, minimally invasive therapies are also emerging as alternatives to surgical biopsy for breast lesions. As imaging techniques improve, the role of imaging will continue to evolve with the goal remaining a decrease in breast cancer morbidity and mortality.
Reddy
Denise H
DH
Northwestern University Feinberg School of Medicine, 675 North St. Clair St., Chicago, Illinois 60611, USA.
Mendelson
Ellen B
EB
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis*; D003952:Diagnostic Imaging / Q000592:standards* / Q000639:trends; D005260:Female; D005544:Forecasting; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008327:Mammography / Q000379:methods; D008403:Mass Screening / Q000592:standards* / Q000639:trends; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods; D012680:Sensitivity and Specificity; D018608:Ultrasonography, Doppler / Q000379:methods
AJR Am J Roentgenol. 2004 Oct;183(4):1149-57
15385322
AJR Am J Roentgenol. 2003 Sep;181(3):619-26
12933450
AJR Am J Roentgenol. 2003 May;180(5):1225-8
12704027
Radiology. 2002 Dec;225(3):801-7
12461264
Radiology. 2002 Nov;225(2):527-36
12409591
Radiology. 2000 Jan;214(1):59-66
10644102
AJR Am J Roentgenol. 2002 Sep;179(3):671-7
12185042
AJR Am J Roentgenol. 2003 Jul;181(1):177-82
12818853
Radiol Clin North Am. 2004 Sep;42(5):919-34, vii
15337425
Cancer. 2004 Apr 1;100(7):1337-44
15042665
Radiology. 2001 Mar;218(3):873-80
11230669
Radiology. 2001 Apr;219(1):192-202
11274556
Radiographics. 2004 May-Jun;24(3):867-78
15143236
J Magn Reson Imaging. 2001 Jun;13(6):868-75
11382946
N Engl J Med. 2004 Jul 29;351(5):427-37
15282350
Br J Cancer. 2004 Aug 31;91(5):861-7
15292936
JAMA. 2004 Sep 15;292(11):1317-25
15367553
AJR Am J Roentgenol. 2002 Nov;179(5):1193-9
12388497
Radiology. 2004 Jul;232(1):197-204
15155893
Radiol Clin North Am. 2004 Sep;42(5):909-18, vii
15337424
Q J Nucl Med Mol Imaging. 2004 Jun;48(2):109-18
15243412
Radiology. 2004 Dec;233(3):830-49
15486214
J Natl Cancer Inst. 2000 Jul 5;92 (13):1081-7
10880551
Rofo. 2003 Jun;175(6):775-9
12811689
Radiology. 2003 Dec;229(3):877-84
14576447
Radiology. 2001 Dec;221(3):641-9
11719658
J Exp Clin Cancer Res. 2002 Sep;21(3 Suppl):115-24
12585665
Eur Radiol. 2002 Jul;12 (7):1697-702
12111060
Radiology. 2001 Sep;220(3):781-6
11526282
J Clin Oncol. 2001 Aug 1;19(15):3524-31
11481359
Eur J Surg Oncol. 2003 Feb;29(1):32-7
12559074
Acad Radiol. 2000 Dec;7(12 ):1085-97
11131053
Radiology. 1999 Dec;213(3):881-8
10580970
Breast Cancer Res Treat. 2002 Mar;72(2):145-52
12038705
AJR Am J Roentgenol. 2004 Feb;182(2):473-80
14736685
Radiol Clin North Am. 2004 Sep;42(5):871-84, vi
15337422
Radiology. 2000 May;215(2):554-62
10796939
AJR Am J Roentgenol. 2003 Jun;180(6):1675-9
12760942
J Natl Cancer Inst. 2001 Jul 18;93(14 ):1095-102
11459871
Radiol Clin North Am. 2004 Sep;42(5):885-908, vi-vii
15337423
Eur Radiol. 2002 Nov;12 (11):2679-83
12386757
AJR Am J Roentgenol. 2003 Nov;181(5):1275-82
14573420
Radiology. 2001 Jul;220(1):13-30
11425968
Radiol Clin North Am. 2004 Sep;42(5):845-51, vi
15337420
AJR Am J Roentgenol. 2000 Dec;175(6):1577-84
11090379
Breast Cancer Res Treat. 2000 Sep;63(1):53-60
11079159
Ann Surg Oncol. 2003 May;10(4):381-8
12734086
AJR Am J Roentgenol. 2001 Nov;177(5):1167-70
11641195
Radiology. 2002 Aug;224(2):569-76
12147858
N Engl J Med. 2004 Jul 29;351(5):497-500
15282358
AJR Am J Roentgenol. 2003 Sep;181(3):687-93
12933460
Radiology. 2002 Oct;225(1):165-75
12355001
Semin Ultrasound CT MR. 2000 Aug;21(4):325-36
11014255
Radiat Med. 2003 Jul-Aug;21(4):166-71
14514123
AJR Am J Roentgenol. 1999 Nov;173(5):1323-9
10541112
Radiology. 2004 Aug;232(2):578-84
15229350
Radiology. 2003 Aug;228(2):569-75
12821770
Radiology. 2000 Jan;214(1):26-8
10644097
Eur J Nucl Med Mol Imaging. 2004 Jun;31 Suppl 1:S97-102
15133635
Radiology. 2000 Apr;215(1):267-79
10751498