[The influence of chloroquine on some biochemical and hematological parameters in patients with critical limb ischemia].
CLI represents a major medical and social problem. The incidence is increasing and currently it was estimated 500-1000 per 1 million inhabitants. We carried out a clinical study (2000-2004) concerning monitoring of some hematological and biochemical markers during reperfusion in patients with CLI. The subject of our interest included possibilities to influence PMNL elastase by medical means and neutrophil-lymphocyte ratio which is considered a reliable and simple parameter to assess severity of clinical conditions.
Mondek
P
P
Klinika cievnej chirurgie, Slovensý ústav srdcových a cievnych chorôb, Bratislava, Slovenská republika. mondo@pobox.sk
Slysko
R
R
Sefránek
V
V
Pechán
I
I
D002738:Chloroquine / Q000627:therapeutic use*; D006801:Humans; D007511:Ischemia / Q000188:drug therapy* / Q000378:metabolism; D007866:Leg / Q000098:blood supply*
D002738:Chloroquine