Using DNA damage responses to prevent and treat skin cancers.
Gilchrest
Barbara A
BA
Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA.
D000818:Animals; D017209:Apoptosis / Q000235:genetics; D064007:Ataxia Telangiectasia Mutated Proteins; D020134:Catalytic Domain / Q000235:genetics; D018797:Cell Cycle Proteins / Q000235:genetics; D016922:Cellular Senescence / Q000235:genetics; D004249:DNA Damage / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics; D016158:Genes, p53 / Q000235:genetics; D006801:Humans; D016350:Leucine Zippers / Q000235:genetics; D019869:Phosphatidylinositol 3-Kinases / Q000235:genetics; D017346:Protein Serine-Threonine Kinases / Q000235:genetics; D013014:SOS Response, Genetics / Q000235:genetics; D012878:Skin Neoplasms / Q000517:prevention & control* / Q000628:therapy; D012880:Skin Pigmentation / Q000235:genetics / Q000528:radiation effects; D019098:Telomerase / Q000235:genetics; D016615:Telomere / Q000235:genetics; D035321:Telomeric Repeat Binding Protein 1 / Q000235:genetics / Q000627:therapeutic use; D035341:Telomeric Repeat Binding Protein 2 / Q000235:genetics; D025521:Tumor Suppressor Proteins / Q000235:genetics; D014466:Ultraviolet Rays / Q000009:adverse effects; D015854:Up-Regulation / Q000235:genetics
D064007:Ataxia Telangiectasia Mutated Proteins; D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; D019869:Phosphatidylinositol 3-Kinases; D017346:Protein Serine-Threonine Kinases; D019098:Telomerase; D035321:Telomeric Repeat Binding Protein 1; D035341:Telomeric Repeat Binding Protein 2; D025521:Tumor Suppressor Proteins; C576324:ATM protein, human