[Biological approach for treatment of degenerative disc diseases].
Intervertebral disc degeneration and associated spinal disorders including low back pain are a leading source of morbidity and a major cause of work disability as well as increased health care costs. Recent advance of molecular biology enable us to utilize these new techniques for understanding disc cell function and mechanisms of disc degeneration. Furthermore, these new technology may open novel therapeutic strategy such as application of growth factors, stem cell therapy, and gene therapy to regenerate degenerated intervertebral discs.
Nishida
Kotaro
K
Department of Orthopedic Surgery, Kobe University Graduate School of Medicine.
Doita
Minoru
M
Takada
Toru
T
Shimomura
Takatoshi
T
Maeno
Koichiro
K
Kakutani
Ken-ichiro
K
Miyamoto
Hiroshi
H
Kurosaka
Masahiro
M
D000818:Animals; D017690:Cell Transplantation; D016207:Cytokines / Q000627:therapeutic use; D015316:Genetic Therapy; D006801:Humans; D017116:Low Back Pain / Q000628:therapy*; D013122:Spinal Diseases / Q000628:therapy*
D016207:Cytokines