Cytochrome P450 enzymes as catalysts of metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco specific carcinogen.
Jalas
John R
JR
Department of Chemistry, University of Minnesota, 207 Pleasant Street SE, Minneapolis, Minnesota 55455, USA.
Hecht
Stephen S
SS
Murphy
Sharon E
SE
D000818:Animals; D002273:Carcinogens / Q000378:metabolism*; D002384:Catalysis; D003577:Cytochrome P-450 Enzyme System / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D008861:Microsomes / Q000378:metabolism; D009602:Nitrosamines / Q000378:metabolism*; D011725:Pyridines / Q000378:metabolism; D013045:Species Specificity; D014026:Nicotiana / Q000378:metabolism*
D002273:Carcinogens; D009602:Nitrosamines; D011725:Pyridines; C016583:4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; D003577:Cytochrome P-450 Enzyme System; C099565:4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol