Clinical and radiological deterioration in a patient with AIDS.
Paradoxical clinical deterioration of miliary tuberculosis, characterized by pulmonary and abdominal manifestations, is reported in a patient with the acquired immunodeficiency syndrome, after initiation of treatment with highly active antiretroviral therapy. Paradoxical reaction was attributed to partial restoration of cell-mediated immunity related to highly effective antiretroviral therapy. Because tuberculosis has a high prevalence in HIV patients and tuberculosis is often characterized by miliary spreading of disease in these patients, it is important to recognize this phenomenon.
De Backer
A I
AI
Department of Radiology, General Hospital Sint-Lucas, Groenebriel 1, 9000, Ghent, Belgium. adelard.debacker@skynet.be
Mortelé
K J
KJ
Bomans
P
P
De Keulenaer
B L
BL
Vanschoubroeck
I J
IJ
Kockx
M M
MM
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D014391:Tuberculosis, Miliary / Q000000981:diagnostic imaging* / Q000276:immunology*; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging* / Q000276:immunology*
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