Pure gastric yolk sac tumor that was diagnosed after curative resection: case report and review of literature.
We recently experienced an 87-yr-old man with gastric yolk sac tumor. Preoperative diagnosis was poorly differentiated adenocarcinoma in the cardia of stomach without apparent metastasis. A total gastrectomy was performed. The precise histological examination after surgery revealed the tumor was composed of pure gastric yolk sac tumor without adenocarcinomatous components. The surgical margin and the resected lymph nodes were histologically negative for the tumor and a curative resection was performed. Five months after the operation, enlargement of the intraabdominal lymph nodes occurred with elevation of serum alpha fetoprotein (AFP), and the patient died 2 mo later. Gastric yolk sac tumors are very rare, and only six cases of gastric yolk sac tumors have been previously reported in the literature. Five out of six cases are accompanied by components of adenocarcinoma, and our present case is the second report of pure gastric yolk sac tumor to the best of our knowledge.
Kanai
Masashi
M
Digestive Disease Center, Kyoto Katsura Hospital, 17 Yamada Hirao-cho, Nishikyo-ku, Kyoto, 615-8256, Japan. kanai@kuhp.kyoto-u.ac.jp
Torii
Ayao
A
Hamada
Akihiko
A
Endo
Yoko
Y
Takeda
Yasuhiro
Y
Yamakawa
Masashi
M
Hikita
Hiroshi
H
Nishikawa
Haruhiro
H
Ochi
Jiro
J
Miura
Kensuke
K
Noguchi
Masashi
M
Kashu
Ippei
I
Sakurai
Takaki
T
D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D000368:Aged; D000369:Aged, 80 and over; D018240:Endodermal Sinus Tumor / Q000473:pathology* / Q000601:surgery*; D017809:Fatal Outcome; D005743:Gastrectomy; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery*
Hum Pathol. 1976 Sep;7(5):595-604
987011
Hum Pathol. 1993 Aug;24(8):927-8
8375864
Cancer. 1999 May 1;85(9):1910-6
10223229
J Clin Gastroenterol. 2000 Jul;31(1):85-8
10914786
Acta Pathol Jpn. 1985 Mar;35(2):497-505
2411108
Hum Pathol. 1985 Sep;16(9):955-8
4040885
Pathol Int. 1999 Jun;49(6):557-62
10469400