Chemical constituents of Murraya siamensis: three coumarins and their anti-tumor promoting effect.
Isolation and structure elucidation of three coumarins, murrayacoumarins A, B, and C, together with eight known coumarins, from the leaves of Murraya siamensis Craib collected in Thailand are described. Results of a primary screening of inhibitory effects of seven of these compounds on 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus early antigen activation in Raji cells are also presented.
Ito
Chihiro
C
Faculty of Pharmacy, Meijo University,Tempaku, Nagoya 468-8503, Japan.
Itoigawa
Masataka
M
Onoda
Saori
S
Hosokawa
Atsuko
A
Ruangrungsi
Nijsiri
N
Okuda
Toshimitsu
T
Tokuda
Harukuni
H
Nishino
Hoyoku
H
Furukawa
Hiroshi
H
D000970:Antineoplastic Agents / Q000494:pharmacology*; D045744:Cell Line, Tumor; D003374:Coumarins / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D032101:Murraya / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry
D000970:Antineoplastic Agents; D003374:Coumarins