title: Mediated electrochemical measurement of the inhibitory effects of furfural and acetic acid on Saccharomyces cerevisiae and Candida shehatae.
abstract: The toxic effects of furfural and acetic acid on two yeasts, Saccharomyces cerevisiae and Candida shehatae, were evaluated using an electrochemical method. Intracellular redox activities were lowered by 40% and 78% for S. cerevisiae and C. shehatae, respectively, by 8 g furfural l(-1), and by 46% and 67%, respectively, by 8 g acetic acid l(-1). The proposed method can accurately measure the effects of inhibitors on cell cultures.
authors.affiliation: Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101 , PR China, zhengyuyang@vip.sina.com.
authors.forename: Jinsheng
authors.initials: J
authors.lastname: Zhao
authors.forename: Min
authors.initials: M
authors.lastname: Wang
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Yang
authors.forename: Qintao
authors.initials: Q
authors.lastname: Gong
authors.forename: Yao
authors.initials: Y
authors.lastname: Lu
authors.forename: Zhengyu
authors.initials: Z
authors.lastname: Yang
mesh_terms: D019342:Acetic Acid / Q000378:metabolism / Q000494:pharmacology* / Q000633:toxicity; D002175:Candida / Q000187:drug effects* / Q000254:growth & development; D004305:Dose-Response Relationship, Drug; D004563:Electrochemistry / Q000379:methods; D005662:Furaldehyde / Q000378:metabolism / Q000494:pharmacology* / Q000633:toxicity; D006863:Hydrogen-Ion Concentration; D010084:Oxidation-Reduction; D015203:Reproducibility of Results; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000254:growth & development
chemical_list: D005662:Furaldehyde; D019342:Acetic Acid