Isolation stress in desert sheep and goats and the influence of pretreatment with xylazine or sodium betaine.
We studied some behavioural, clinical, biochemical and haematological variables in Desert (Najdi) sheep and goats subjected to the acute stressful stimulus of isolation from the flock, and the influence of pretreatment with xylazine (n = 6) or sodium betaine (n = 6). The isolation stress resulted in increased vocalization and in variable and statistically nonsignificant increases in heart, pulse and respiratory rates. Isolation caused significant increases in the plasma concentrations of cortisol (from about 35.2 to about 83.8 mmol/L) and glucose (from 3.1 to 4.2 mmol/L), and a decrease in that of magnesium (from 0.82 to 0.65 mmol/L). The endogenous thiocyanate concentration was unaffected. The isolation stress also significantly decreased the haematocrit (PCV), and the number of lymphocytes, and increased the concentration of haemoglobin. Pretreatment of sheep and goats with xylazine at a dose of 0.01 mg/kg by the intravenous route significantly ameliorated the effects induced by the stressful stimulus. The effects of pretreatment of the two species with sodium betaine (10 mg/kg) produced variable and nonsignificant effects. There were no significant differences between sheep and goats in the responses to the isolation stress, except in vocalization, which was greater in sheep than in goats.
Al-Qarawi
A A
AA
Department of Veterinary Medicine, King Saud University, PO Box 10158, Buryadah, Al-Gaseem, Saudi Arabia.
Ali
B H
BH
D000316:Adrenergic alpha-Agonists / Q000494:pharmacology*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001622:Betaine / Q000494:pharmacology; D003889:Desert Climate; D006041:Goats / Q000097:blood / Q000523:psychology*; D008297:Male; D012756:Sheep / Q000097:blood / Q000523:psychology*; D012934:Social Isolation / Q000523:psychology*; D013045:Species Specificity; D013315:Stress, Psychological / Q000097:blood / Q000188:drug therapy*; D014991:Xylazine / Q000494:pharmacology*
D000316:Adrenergic alpha-Agonists; D014991:Xylazine; D001622:Betaine
Adv Vet Sci Comp Med. 1980;24:179-210
7006340
Res Vet Sci. 1994 Mar;56(2):234-9
8191014
J Vet Pharmacol Ther. 1997 Aug;20(4):262-6
9280365
Hepatology. 2002 Oct;36(4 Pt 1):829-39
12297830
Br Vet J. 1992 Mar-Apr;148(2):119-28
1576515
Skin Res Technol. 2003 Feb;9(1):50-8
12535285
Avian Dis. 1992 Jul-Sep;36(3):688-92
1417599
J Vet Pharmacol Ther. 1987 Jun;10(2):119-26
3612939
Zentralbl Veterinarmed A. 1993 Oct;40(8):631-8
8279214
Br Vet J. 1991 Jan-Feb;147(1):42-8
2018916
Endokrynol Pol. 1991;42(4):567-74
1364508
Can Vet J. 2003 Jun;44(6):496-9
12839246
Vet Res Commun. 2001 Aug;25(6):503-10
11519681
Zentralbl Veterinarmed A. 1992 Aug;39(6):401-3
1414084
Res Vet Sci. 1990 Mar;48(2):262-3
2333437
Vet Rec. 1998 Aug 22;143(8):212-9
9770763