title: Extraction of overt verbal response from the acoustic noise in a functional magnetic resonance imaging scan by use of segmented active noise cancellation.
abstract: A method to extract the subject's overt verbal response from the obscuring acoustic noise in an fMRI scan is developed by applying active noise cancellation with a conventional MRI microphone. Since the EPI scanning and its accompanying acoustic noise in fMRI are repetitive, the acoustic noise in one time segment was used as a reference noise in suppressing the acoustic noise in subsequent segments. However, the acoustic noise from the scanner was affected by the subject's movements, so the reference noise was adaptively adjusted as the scanner's acoustic properties varied in time. This method was successfully applied to a cognitive fMRI experiment with overt verbal responses.
authors.affiliation: Brain Imaging Research Center, University of Pittsburgh & Carnegie Mellon University, 3025 East Carson Street, Pittsburgh, PA 15203, USA. kjj1@pitt.edu
authors.forename: Kwan-Jin
authors.initials: KJ
authors.lastname: Jung
authors.forename: Parikshit
authors.initials: P
authors.lastname: Prasad
authors.forename: Yulin
authors.initials: Y
authors.lastname: Qin
authors.forename: John R
authors.initials: JR
authors.lastname: Anderson
mesh_terms: D000162:Acoustics; D016477:Artifacts; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009622:Noise; D019047:Phantoms, Imaging; D013067:Speech Perception
references.citation: Science. 2002 May 24;296(5572):1476-9
references.pmid: 12029136
references.citation: J Acoust Soc Am. 2000 Oct;108(4):1683-96
references.pmid: 11051496
references.citation: J Acoust Soc Am. 2001 Jan;109(1):216-31
references.pmid: 11206150
references.citation: IEEE Trans Biomed Eng. 1999 Feb;46(2):186-91
references.pmid: 9932340
references.citation: Neuroimage. 1999 Dec;10(6):642-57
references.pmid: 10600410
references.citation: J Acoust Soc Am. 2001 Dec;110(6):3041-54
references.pmid: 11785805
references.citation: Magn Reson Imaging. 1997;15(7):815-22
references.pmid: 9309612
references.citation: Magn Reson Imaging. 1997;15(3):319-22
references.pmid: 9201679
references.citation: J Magn Reson Imaging. 2002 Nov;16(5):497-510
references.pmid: 12412026
references.citation: Hum Brain Mapp. 2003 Nov;20(3):123-41
references.pmid: 14601139
references.citation: Neuroreport. 1997 Jan 20;8(2):561-5
references.pmid: 9080448
references.citation: J Cogn Neurosci. 2004 May;16(4):637-53
references.pmid: 15165353
references.citation: Neuroimage. 2003 Nov;20(3):1865-71
references.pmid: 14642496