Hybrid biosynthesis by targeted inactivation of polyketide synthases in the mycinamicin producer, Micromonospora griseorubida.
Anzai
Yojiro
Y
Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan.
Kinoshita
Kenji
K
Seki
Tomoe
T
Kato
Fumio
F
D004791:Enzyme Inhibitors / Q000378:metabolism* / Q000494:pharmacology; D005285:Fermentation; D018942:Macrolides / Q000378:metabolism* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008847:Micromonospora / Q000201:enzymology* / Q000378:metabolism; D048630:Polyketide Synthases / Q000037:antagonists & inhibitors*; D021241:Spectrometry, Mass, Electrospray Ionization
D004791:Enzyme Inhibitors; D018942:Macrolides; C026686:mycinamicins; D048630:Polyketide Synthases