Toxic and repellent effects of Baccharis salicifolia essential oil on Tribolium castaneum.
Allelochemical effects were observed when Tribolium castaneum (Herbst) adults were treated with Baccharis salicifolia (Ruiz & Pavon) Pers essential oil. The main biological activities were toxicity and repellence. Terpenes present in the essential oil were identified by GC-MS, and some authentic samples were tested to assess their activity individually. The most acutely toxic compounds after 3 days were beta-pinene and pulegone. Most of the monoterpenes elicited symptoms indicative of neurotoxicity. The most repellent compound was alpha-terpineol. Toxic and repellent effects of chemical derivatives of the major sesquiterpene present in B salicifolia essential oil, as well as a series of monoterpenes, were evaluated in order to investigate structure-activity relationships. The reduced derivatives of the monoterpenes and sesquiterpenes were more repellent that their carbonyl analogues. In addition, unsaturation in the germacrane skeleton enhanced repellent activity.
García
Matías
M
INTEQUI-CONICET, Departamento de Química-Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, Chacabuco y Pedernera, 5700, San Luis, Argentina.
Donadel
Osvaldo J
OJ
Ardanaz
Carlos E
CE
Tonn
Carlos E
CE
Sosa
Marta E
ME
D000818:Animals; D031175:Baccharis / Q000737:chemistry*; D007302:Insect Repellents; D007306:Insecticides; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry / Q000494:pharmacology; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D012717:Sesquiterpenes / Q000737:chemistry / Q000494:pharmacology; D014231:Tribolium / Q000502:physiology*
D007302:Insect Repellents; D007306:Insecticides; D039821:Monoterpenes; D009822:Oils, Volatile; D012717:Sesquiterpenes