title: Heterochromatin: on the ADAR radar?
abstract: Vigilin proteins, the absence of which is known to cause abnormalities in heterochromatin, have been found to bind edited RNAs. Molecular complexes including vigilin comprise proteins involved with RNA editing and with DNA repair, making connections between these processes and RNA-based silencing mechanisms.
authors.affiliation: Division of Biological Sciences, University of Missouri, Columbia, Missouri 65211, USA.
authors.forename: H R
authors.initials: HR
authors.lastname: Fernandez
authors.forename: H H
authors.initials: HH
authors.lastname: Kavi
authors.forename: W
authors.initials: W
authors.lastname: Xie
authors.forename: J A
authors.initials: JA
authors.lastname: Birchler
mesh_terms: D001324:Autoantigens / Q000378:metabolism; D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism*; D053487:DEAD-box RNA Helicases; D004260:DNA Repair; D051747:DNA-Activated Protein Kinase; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism; D006570:Heterochromatin / Q000235:genetics*; D008954:Models, Biological; D009363:Neoplasm Proteins; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D012313:RNA / Q000378:metabolism*; D020365:RNA Helicases / Q000378:metabolism; D034622:RNA Interference; D016601:RNA-Binding Proteins / Q000235:genetics / Q000378:metabolism*
chemical_list: D001324:Autoantigens; D002352:Carrier Proteins; D004268:DNA-Binding Proteins; C491076:Dp1 protein, Drosophila; D029721:Drosophila Proteins; D006570:Heterochromatin; D009363:Neoplasm Proteins; D016601:RNA-Binding Proteins; C075197:high density lipoprotein binding protein; D012313:RNA; D051747:DNA-Activated Protein Kinase; D017346:Protein Serine-Threonine Kinases; C098487:DHX9 protein, human; D053487:DEAD-box RNA Helicases; D020365:RNA Helicases