Use of plant protein hydrolysates for varicella virus production in serum-free medium.
Serum-free media containing no animal-derived components were assessed for their efficacy to produce live attenuated varicella virus. Serum-free medium containing an ultrafiltrate of soy protein acid hydrolysate and lipid resulted in a viral production yield comparable to media containing fetal bovine serum, indicating that varicella virus can be produced without the risk of contamination associated with the use of bovine serum.
Chun
Bok-Hwan
BH
College of Life and Environmental Sciences, Korea University, 136-713, Sungbuk-gu, Anam-dong 5-1, Seoul, Korea.
Kwon Lee
Yong
Y
Bang
Won-Gi
WG
Chung
Namhyun
N
D002460:Cell Line; D016895:Culture Media, Serum-Free / Q000378:metabolism*; D014645:Herpesvirus 3, Human / Q000254:growth & development*; D006801:Humans; D008168:Lung / Q000378:metabolism* / Q000821:virology*; D011492:Protein Hydrolysates / Q000378:metabolism*; D013025:Glycine max / Q000378:metabolism; D014779:Virus Replication / Q000502:physiology*
D016895:Culture Media, Serum-Free; D011492:Protein Hydrolysates