title: New criterial for cytologic diagnosis of adenoid cystic carcinoma.
abstract: OBJECTIVE
  To formulate new criteria for adenoid cystic carcinoma (ADCC).
  
  
  METHODS
  The usefulness of 17 items for a cytologically definitive diagnosis of ADCC was examined. The frequency (- - +++) of the 17 items in 18 cases of ADCC and 10 non-ADCC cases (pleomorphic adenoma, basal cell adenoma, myoepithelioma and epithelial-myoepithelial carcinoma) that displayed mimicking cytology was examined cytologically. The total score for cases of ADCC was compared with that for non-ADCC cases.
  
  
  RESULTS
  The 17 items included broad intercellular spaces with adhesion; green, granular/cobwebby cytoplasm with translucent intercellular matrix with Papanicolaou staining; coarse hyperchromatin with little nuclear clearing; indistinct and partially distinct nucleoli; small nuclei; broad, smooth margin (SM) space; and translucent M/HG/SM. All cases with a total score of > 21 were ADCC (93.8%). All cases with a total score of < 12 were non-ADCC (87.5%).
  
  
  CONCLUSIONS
  The 17 items appear to be useful as new criteria for ADCC.
authors.affiliation: Department of Biochemistry, Akebono Medical Welfare Center, and Pathology Division, Yamanashi Prefectural Central Hospital, Yamanashi, Japan. hara2@nns.ne.jp
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Hara
authors.forename: Toshio
authors.initials: T
authors.lastname: Oyama
authors.forename: Koichi
authors.initials: K
authors.lastname: Suda
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology; D000236:Adenoma / Q000175:diagnosis / Q000473:pathology; D008949:Adenoma, Pleomorphic / Q000175:diagnosis / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D003528:Carcinoma, Adenoid Cystic / Q000175:diagnosis* / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009208:Myoepithelioma / Q000175:diagnosis / Q000473:pathology; D012468:Salivary Gland Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D013194:Staining and Labeling