[Imipenem and cefepime in empirical therapy of infectious complications after radical surgeries in patients with invasive cancer of the urinary bladder].
Urinary tract injection (UTI) is one of the main causes of severe complications and death in oncologic patients and particularly in patients with invasive cancer of the urinary bladder. In our Clinic an up-to-date system for infection control recording all cases of UTI in oncologic patients is being exploited since 2001. The paper presents the data on our observations during the period from 2001 to 2003 concerning typical UTI in patients with invasive cancer of the urinary bladder, etiological agents of UTI and their susceptibility to a wide range of antibacterials, including imipenem and cefepime, a 4th generation cephalosporin, used for adequate therapy of UTI in oncourologic patients.
Mitrokhin
S D
SD
Gordeev
Iu N
IuN
Sokolov
A A
AA
Zabaznyĭ
N P
NP
Avilova
N D
ND
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D000077723:Cefepime; D002511:Cephalosporins / Q000494:pharmacology / Q000627:therapeutic use*; D015653:Cystectomy; D005260:Female; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D015378:Imipenem / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000188:drug therapy* / Q000382:microbiology; D012189:Retrospective Studies; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000601:surgery*; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D015378:Imipenem; D000077723:Cefepime