title: An efficient synthesis of propargylamines via C-H activation catalyzed by copper(I) in ionic liquids.
abstract: A readily available copper(I) catalyst, in an ionic liquid, can effect three-component coupling of aldehydes, amines and alkynes to generate propargylamines in high yields.
authors.affiliation: Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie Ottawa, ON, Canada K1N 6N5.
authors.forename: Soon Bong
authors.initials: SB
authors.lastname: Park
authors.forename: Howard
authors.initials: H
authors.lastname: Alper
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry; D000588:Amines / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D052578:Ionic Liquids / Q000737:chemistry*; D015394:Molecular Structure; D010293:Pargyline / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D011437:Propylamines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D000480:Alkynes; D000588:Amines; D052578:Ionic Liquids; D011437:Propylamines; C009054:propargylamine; D003300:Copper; D010293:Pargyline