title: [Study of diffusion of muscone in different inclusion complexes and liposome through mouse (correction of rat) skin in vitro].
abstract: OBJECTIVE
  To compare the penetrating rate of muscone in different inclusion complexes and liposome.
  
  
  METHODS
  The transdermal effect of muscone in different inclusion complexes and liposome was studied comparatively on mouse [corrected] skin with 40% EtOH as the absorption solution and with an improved Franz diffuse cell.
  
  
  RESULTS
  Among the different inclusion complexes and liposome, the penetrating rate of muscone in the HP-beta-cyclodextrin inclusion and the liposome were higher than muscone, and that of muscone in the beta-cyclodextrin inclusion is the lowest.
  
  
  CONCLUSIONS
  The HP-beta-cyclodextrin inclusion and the liposome can hence the muscone transdermal speed.
authors.affiliation: Nanjing university of Traditional Chinese Medicine, Nanjing 210029, China. diliuqing@yahoo.com.cn
authors.forename: Liu-qing
authors.initials: LQ
authors.lastname: Di
authors.forename: Chun-qin
authors.initials: CQ
authors.lastname: Mao
authors.forename: Hui
authors.initials: H
authors.lastname: Xie
authors.forename: Rong
authors.initials: R
authors.lastname: Guo
authors.forename: Ming
authors.initials: M
authors.lastname: Xue
authors.forename: Ke
authors.initials: K
authors.lastname: Yan
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Hong-yan
authors.initials: HY
authors.lastname: Li
mesh_terms: D000073738:2-Hydroxypropyl-beta-cyclodextrin; D000818:Animals; D003516:Cycloparaffins / Q000008:administration & dosage / Q000493:pharmacokinetics; D004337:Drug Carriers; D004355:Drug Stability; D066298:In Vitro Techniques; D008081:Liposomes; D051379:Mice; D012869:Skin Absorption; D047392:beta-Cyclodextrins
chemical_list: D003516:Cycloparaffins; D004337:Drug Carriers; D008081:Liposomes; D047392:beta-Cyclodextrins; D000073738:2-Hydroxypropyl-beta-cyclodextrin; C031021:muscone