Skin disorders in patients transplanted in childhood.
Only few data are available on skin disorders in pediatric organ transplant recipients. In order to describe the whole range of dermatological diseases in a population of pediatric organ transplant recipients, we studied a group of 217 consecutive organ transplant recipients (168 kidney, 29 heart, 19 liver, one lung) aged <18 years at transplantation followed at a single center. A total of 193 patients showed at least one skin disorder; 149 had more than one skin disease. The most common skin infections were warts (24.4%), pityriasis versicolor (20.7%), folliculitis (12.9%), intertrigo (6.5%); the most common drug side effects were hypertrichosis (69.6%), steroid acne (39.6%), gingival hyperplasia (29%) and severe xerosis (20.7%). Two patients (0.9%) developed nonmelanoma skin cancer. Our study summarizes the main skin complications in patients transplanted in childhood and underlines the necessity of regular dermatologic surveillance of these patients.
Fortina
Anna Belloni
AB
Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128 Padua, Italy. belloni@pediatria.unipd.it
Piaserico
Stefano
S
Alaibac
Mauro
M
Caforio
Alida L P
AL
Brandolisio
Lara
L
Zacchello
Graziella
G
Zanon
Giovanni Franco
GF
Zancan
Lucia
L
Peserico
Andrea
A
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007223:Infant; D007231:Infant, Newborn; D007239:Infections / Q000453:epidemiology; D008297:Male; D016377:Organ Transplantation / Q000009:adverse effects*; D012871:Skin Diseases / Q000453:epidemiology*
D007166:Immunosuppressive Agents