title: Recovery of N100 component of auditory event-related potentials and EEG after cardiac arrest during propofol sedation.
abstract: We report on the EEG monitoring of a patient who suffered an episode of postoperative ventricular fibrillation (VF) following coronary artery bypass grafting (CABG). VF initially caused a considerable suppression and slowing of the EEG. The recovery of cerebral function was evaluated by recording both EEG and auditory event related potentials (ERPs). Six hours after the episode of VF, when the patient was asleep but arousable to voice command, the N100 component of the auditory ERPs had recovered to the level measured before the operation, whereas the EEG was still very slow for that level of sedation. This may have been due to VF having less effect on the N100 component than on the background EEG. Our findings suggest that measuring evoked potentials may improve the evaluation of brain function after cardiac arrest.
authors.affiliation: Department of Clinical Neurophysiology, Kuopio University Hospital, Finland. susanne.westeren-punnonen@kuh.fi
authors.forename: S M
authors.initials: SM
authors.lastname: Westerén-Punnonen
authors.forename: H
authors.initials: H
authors.lastname: Yppärilä
authors.forename: T
authors.initials: T
authors.lastname: Musialowicz
authors.forename: I
authors.initials: I
authors.lastname: Korhonen
authors.forename: M
authors.initials: M
authors.lastname: Hynynen
authors.forename: J
authors.initials: J
authors.lastname: Partanen
mesh_terms: D000368:Aged; D016292:Procedural Sedation; D001026:Coronary Artery Bypass; D004569:Electroencephalography / Q000379:methods; D005072:Evoked Potentials, Auditory; D005260:Female; D006323:Heart Arrest / Q000503:physiopathology*; D006801:Humans; D006993:Hypnotics and Sedatives; D008991:Monitoring, Physiologic / Q000379:methods; D011182:Postoperative Care / Q000379:methods; D011183:Postoperative Complications / Q000503:physiopathology*; D015742:Propofol
chemical_list: D006993:Hypnotics and Sedatives; D015742:Propofol