Microwave-promoted Heck coupling using ultralow metal catalyst concentrations.
We show that Heck couplings can be performed in water using microwave heating and Pd catalyst concentrations as low as 500 ppb. The methodology is simple; all that is required as the catalyst is a stock solution of palladium.
Arvela
Riina K
RK
Department of Chemistry, University of Connecticut, Unit 3060, 55 North Eagleville Road, Storrs, Connecticut 06269-3060, USA.
Leadbeater
Nicholas E
NE
D000840:Anisoles / Q000737:chemistry; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods; D006358:Hot Temperature; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis* / Q000737:chemistry; D006846:Hydrocarbons, Halogenated / Q000138:chemical synthesis* / Q000737:chemistry; D008872:Microwaves; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D020058:Styrene / Q000737:chemistry; D014867:Water / Q000737:chemistry
D000840:Anisoles; D006841:Hydrocarbons, Aromatic; D006846:Hydrocarbons, Halogenated; D009942:Organometallic Compounds; D014867:Water; D020058:Styrene; D010165:Palladium