Transcriptome of Treponema pallidum: gene expression profile during experimental rabbit infection.
RNA transcript levels in the syphilis spirochete Treponema pallidum subsp. pallidum (Nichols) isolated from experimentally infected rabbits were determined by the use of DNA microarray technology. This characterization of the T. pallidum transcriptome during experimental infection provides further insight into the importance of gene expression levels for the survival and pathogenesis of this bacterium.
Smajs
David
D
Human Genome Sequencing Center, University of Texas-Houston Medical School, Houston, Texas, USA. dsmajs@med.muni.cz
McKevitt
Matthew
M
Howell
Jerrilyn K
JK
Norris
Steven J
SJ
Cai
Wei-Wen
WW
Palzkill
Timothy
T
Weinstock
George M
GM
D000818:Animals; D015870:Gene Expression; D020869:Gene Expression Profiling / Q000379:methods*; D020411:Oligonucleotide Array Sequence Analysis; D016366:Open Reading Frames; D012329:RNA, Bacterial; D012333:RNA, Messenger; D011817:Rabbits; D013587:Syphilis / Q000382:microbiology; D014210:Treponema pallidum / Q000235:genetics* / Q000378:metabolism* / Q000472:pathogenicity
D012329:RNA, Bacterial; D012333:RNA, Messenger
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