Assessment of portal vein invasion in pancreatic cancer by fusion 3-dimensional ultrasonography.
OBJECTIVE
The purpose of this study was to assess the usefulness of a newly developed imaging technique, fusion 3-dimensional ultrasonography (3DUS) in the diagnosis of portal vein (PV) invasion in patients with pancreatic cancer (PC).


METHODS
Fourteen patients with proven PC were examined by fusion 3DUS presented as shaded volume-rendering and multiplanar reconstruction images. The surgical findings were obtained in all patients (12 with resection and 2 without). The findings were compared with those of 2-dimensional ultrasonography (2DUS), contrast-enhanced computed tomography (CT), dynamic CT (DCT), angiography, and surgical findings. Portal vein invasion was assessed by 3 independent radiologists for each modality, and objectivity of the assessment was examined by interobserver variability analysis (kappa value).


RESULTS
On the basis of surgical findings, the accuracy rates of 2DUS, fusion 3DUS, DCT, and angiography were 78.6%, 92.9%, 85.3%, and 66.7%, respectively. The kappa values of 2DUS, fusion 3DUS, DCT, and angiography for PV invasion were 0.57, 0.90, 0.63, and 0.49, respectively, being most objective in fusion 3DUS.


CONCLUSIONS
Fusion 3DUS is useful for diagnosis of PV invasion of PC.
Kobayashi
Akitoshi
A
Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuou-ku, Chiba-shi, Chiba 260-8670, Japan.
Yamaguchi
Taketo
T
Ishihara
Takeshi
T
Ohshima
Tadashi
T
Ohno
Izumi
I
Seza
Katsushi
K
Shirai
Yoshihiko
Y
Sudo
Kentaro
K
Nakagawa
Akihiko
A
Tadenuma
Hiroshi
H
Nakamura
Kazuyoshi
K
Saisho
Hiromitsu
H
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010190:Pancreatic Neoplasms / Q000473:pathology*; D011169:Portal Vein / Q000000981:diagnostic imaging*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D019043:Vascular Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*