title: Lipid peroxidation in the peritoneal fluid of infertile women with peritoneal endometriosis.
abstract: OBJECTIVE
  To assess the level of lipid peroxidation in the peritoneal fluid of infertile women with peritoneal endometriosis and of fertile disease-free controls.
  
  
  METHODS
  Level of lipid peroxidation (malondialdeyde, malondialdeyde with copper addition, and cholest-3,5-dien-7-one) was measured in the peritoneal fluid obtained from 21 women with endometriosis-related infertility and from 21 fertile women having tubal ligation.
  
  
  RESULTS
  : The level of lipid peroxidation did not differ significantly (P > 0.05) according to the stage of endometriosis. The level of lipid peroxidation (malondialdeyde, malondialdeyde with the addition of copper, and cholest-3,5-dien-7-one) did not differ significantly (P > 0.05) between patients with endometriosis-related infertility (0.07 nmol/ml, 0.34 nmol/ml, 0.24 microg/ml, respectively) and disease-free controls (0.04 nmol/ml, 0.21 nmol/ml, 0.25 microg/ml, respectively).
  
  
  CONCLUSIONS
  The level of lipid peroxidation did not differ between women with endometriosis-related infertility and fertile disease-free controls, suggesting that increased reactive oxygen species may not be one of the factors responsible for compromised fertility in patients with endometriosis.
authors.affiliation: Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Av. Bandeirantes, 3900, 14049-900 Ribeirão Preto, São Paulo, Brazil.
authors.forename: Vivian F
authors.initials: VF
authors.lastname: do Amaral
authors.forename: S P
authors.initials: SP
authors.lastname: Bydlowski
authors.forename: T C
authors.initials: TC
authors.lastname: Peranovich
authors.forename: Paula A A S
authors.initials: PA
authors.lastname: Navarro
authors.forename: M T R
authors.initials: MT
authors.lastname: Subbiah
authors.forename: Rui A
authors.initials: RA
authors.lastname: Ferriani
mesh_terms: D000328:Adult; D001202:Ascitic Fluid / Q000737:chemistry; D004715:Endometriosis / Q000150:complications*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology*; D015227:Lipid Peroxidation / Q000502:physiology*; D017382:Reactive Oxygen Species / Q000032:analysis
chemical_list: D017382:Reactive Oxygen Species