Much anticipated--the bioactive conformation of epothilone and its binding to tubulin.
Heinz
Dirk W
DW
Division of Structural Biology, Gesellschaft für Biotechnologische, Forschung, 38124 Braunschweig, Germany. dih@gbf.de
Schubert
Wolf-Dieter
WD
Höfle
Gerhard
G
D001426:Bacterial Proteins / Q000737:chemistry; D001665:Binding Sites / Q000235:genetics; D003461:Crystallography; D003577:Cytochrome P-450 Enzyme System / Q000737:chemistry / Q000378:metabolism; D034261:Epothilones / Q000737:chemistry* / Q000378:metabolism; D008870:Microtubules / Q000737:chemistry; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D009154:Mutation; D010088:Oxidoreductases / Q000737:chemistry; D017239:Paclitaxel / Q000737:chemistry / Q000378:metabolism; D011485:Protein Binding; D014404:Tubulin / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism
D001426:Bacterial Proteins; D034261:Epothilones; D014404:Tubulin; C093787:epothilone A; D003577:Cytochrome P-450 Enzyme System; C403885:EpoK protein, Polyangium cellulosum; D010088:Oxidoreductases; C430592:ixabepilone; D017239:Paclitaxel; C093788:epothilone B