Functional electrical stimulation of denervated muscles: basic issues.
Denervating injuries result in flaccid paralysis and severe atrophy of the affected muscles. This work reviews the potential for functional restoration of such muscles by electrical stimulation, focusing on the basic scientific issues.
Salmons
Stanley
S
Muscle Research Group, Department of Human Anatomy and Cell Biology University of Liverpool, Liverpool, UK. s.salmons@liverpool.ac.uk
Ashley
Zoe
Z
Sutherland
Hazel
H
Russold
Michael F
MF
Li
Feng
F
Jarvis
Jonathan C
JC
D004599:Electric Stimulation Therapy / Q000379:methods*; D006801:Humans; D009119:Muscle Contraction / Q000502:physiology; D009121:Muscle Denervation / Q000009:adverse effects*; D018485:Muscle Fibers, Skeletal / Q000502:physiology; D018482:Muscle, Skeletal / Q000294:innervation / Q000502:physiology*; D009133:Muscular Atrophy / Q000503:physiopathology / Q000628:therapy*; D010243:Paralysis / Q000503:physiopathology / Q000628:therapy*; D012038:Regeneration / Q000502:physiology*