[Pneumococcal vaccination in obstructive lung diseases -- what can we expect?].
Many countries' guidelines recommend pneumococcal vaccination for patients suffering from obstructive airway disease. This paper reviews the literature as to immunogenicity and safety of this immunization. There is no evidence for a negative effect of pneumococcal vaccination on these patients. Only a few data exist on the preventive impact of pneumococcal vaccination as to exacerbations of obstructive airway diseases. Existing studies mostly took up this question as a side aspect. The effect in children and adults appears limited. On the other hand, the pneumococcal conjugate vaccine prevents life-threatening invasive infections in children younger than 5 years, and pneumococcal polysaccharide vaccine protects healthy adults against bacteriaemic pneumonia. Thus, pneumococcal vaccination of patients suffering from obstructive airway disease is recommendable.
Rose
M
M
Kinderklinik der JW Goethe Universität, Pneumologie und Allergologie, Frankfurt. Markus.Rose@kgu.de
Lode
H
H
de Roux
A
A
Zielen
S
S
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D006801:Humans; D018928:Immunity, Mucosal; D008173:Lung Diseases, Obstructive / Q000209:etiology / Q000517:prevention & control*; D008875:Middle Aged; D022242:Pneumococcal Vaccines; D011018:Pneumonia, Pneumococcal / Q000150:complications / Q000517:prevention & control*; D013296:Streptococcus pneumoniae / Q000254:growth & development / Q000276:immunology
D022242:Pneumococcal Vaccines