title: Inverse relationship between cord blood adiponectin concentrations and the number of cigarettes smoked during pregnancy.
abstract: BACKGROUND
  Maternal smoking is linked with several neonatal metabolic disorders. Adiponectin is an adipose-specific hormone with anti-inflammatory and antiatherogenic properties.
  
  
  OBJECTIVE
  The aim of this study was to evaluate the effect of maternal smoking on cord blood adiponectin concentrations.
  
  
  METHODS
  We evaluate the effect of maternal smoking on cord blood adiponectin concentrations comparing 14 full-term and seven preterm newborns born to mothers who smoked during pregnancy with 77 full-term and 10 preterm neonates born to non-smokers mothers.
  
  
  RESULTS
  Maternal smoking during pregnancy was significantly associated with decreased adiponectin levels of preterm newborns (p < 0.05).
  
  
  CONCLUSIONS
  Our findings also reveal a significant relationship between the reported number of cigarettes smoked during pregnancy and cord blood adiponectin concentrations (p = 0.01), suggesting that this association could have a causal relationship.
authors.affiliation: Department of Pediatrics, University of Campinas-UNICAMP, São Paulo, Brazil. doctorpardo@hotmail.com
authors.forename: I M C G
authors.initials: IM
authors.lastname: Pardo
authors.forename: B
authors.initials: B
authors.lastname: Geloneze
authors.forename: M A
authors.initials: MA
authors.lastname: Tambascia
authors.forename: A A
authors.initials: AA
authors.lastname: Barros
mesh_terms: D052242:Adiponectin; D000328:Adult; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D006801:Humans; D007230:Infant, Low Birth Weight / Q000097:blood; D007231:Infant, Newborn; D007234:Infant, Premature / Q000097:blood; D036341:Intercellular Signaling Peptides and Proteins / Q000097:blood*; D009035:Mothers; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood*; D012907:Smoking / Q000009:adverse effects*
chemical_list: D052242:Adiponectin; D036341:Intercellular Signaling Peptides and Proteins