Selecting B cells and plasma cells to memory.
Humoral immunity appears to be based on immunological memory provided by memory plasma cells, which secrete protective antibodies, and memory B cells, which react to antigen challenge by differentiating into plasma cells. How these differentiation pathways relate to each other, how cells are selected into these memory populations, and how these populations are maintained remains enigmatic.
Dörner
Thomas
T
University Hospital Berlin and Deutsches Rheumaforschungszentrum Berlin, 10098 Berlin, Germany. thomas.doerner@charite.de
Radbruch
Andreas
A
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D006801:Humans; D007156:Immunologic Memory; D010950:Plasma Cells / Q000276:immunology
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