Aerobic oxidative amination of unactivated alkenes catalyzed by palladium.
The first examples of palladium-catalyzed oxidative amination of unactivated alkyl olefins have been identified. To be successful, these reactions must be conducted under cocatalyst-free conditions that involve direct dioxygen-coupled turnover of the palladium catalyst. The oxidative amination products of norbornene and other cyclic alkenes implicate a cis-aminopalladation mechanism.
Brice
Jodie L
JL
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706, USA.
Harang
Jenna E
JE
Timokhin
Vitaliy I
VI
Anastasi
Natia R
NR
Stahl
Shannon S
SS
D000332:Aerobiosis; D000475:Alkenes / Q000737:chemistry*; D000586:Amination; D000588:Amines / Q000138:chemical synthesis*; D002384:Catalysis; D007097:Imines / Q000138:chemical synthesis*; D009636:Norbornanes / Q000737:chemistry; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry
D000475:Alkenes; D000588:Amines; D007097:Imines; D009636:Norbornanes; D010165:Palladium