No observed effect of GB virus C coinfection on disease progression in a cohort of African woman infected with HIV-1 or HIV-2.
We studied mortality among subjects with human immunodeficiency virus (HIV)-1 and HIV-2 infection in relation to GB virus (GBV)-C coinfection. No significant differences in mortality were seen between subjects with and subjects without GBV-C coinfection who also had either HIV-1 or HIV-2 infection. No association between GBV-C and HIV plasma virus loads or CD4 cell count was observed.
Kaye
Steve
S
MRC Laboratories, Fajara, The Gambia. skaye@mrc.gm
Howard
Mark
M
Alabi
Abraham
A
Hansmann
Andreas
A
Whittle
Hilton
H
Schim van der Loeff
Maarten
M
D000293:Adolescent; D000328:Adult; D000349:Africa / Q000453:epidemiology; D018791:CD4 Lymphocyte Count; D015331:Cohort Studies; D018450:Disease Progression; D005260:Female; D018178:Flaviviridae Infections / Q000150:complications*; D029407:GB virus C / Q000502:physiology*; D015658:HIV Infections / Q000150:complications* / Q000401:mortality* / Q000821:virology; D015497:HIV-1 / Q000302:isolation & purification; D015498:HIV-2 / Q000302:isolation & purification; D006525:Hepatitis, Viral, Human / Q000150:complications* / Q000821:virology; D006801:Humans; D019562:Viral Load