title: SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci.
abstract: In multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses of linkage disequilibrium (LD) between markers, haplotype distributions and many chi-square/p values with a large number of samples has been sought for long. In order to achieve the goal of obtaining meaningful results directly from raw data, we developed a robust and user-friendly software platform with a series of tools for analysis in association study with high efficiency. The platform has been well evaluated by several sets of real data.
authors.affiliation: Bio-X Life Science Research Center, Shanghai Jiao Tong University, Shanghai, China.
authors.forename: Yong Yong
authors.initials: YY
authors.lastname: Shi
authors.forename: Lin
authors.initials: L
authors.lastname: He
mesh_terms: D020022:Genetic Predisposition to Disease; D006239:Haplotypes; D006801:Humans; D020407:Internet; D015810:Linkage Disequilibrium; D011110:Polymorphism, Genetic; D012984:Software