Model systems based on experimental animals for studies on drug metabolism in man: (mini)pig cytochromes P450 3A29 and 2E1.
Anzenbacherová
Eva
E
Institute of Medical Chemistry and Biochemistry, Faculty of Medicine, Palacky University, Hnevotinska 3, CZ-775 15 Olomouc, Czech Republic. anzen@tunw.upol.cz
Baranová
Jana
J
Zuber
Roman
R
Pechová
Alena
A
Anzenbacher
Pavel
P
Soucek
Pavel
P
Martínková
Jirina
J
D000818:Animals; D001189:Aryl Hydrocarbon Hydroxylases / Q000502:physiology*; D019392:Cytochrome P-450 CYP2E1 / Q000502:physiology*; D051544:Cytochrome P-450 CYP3A; D006801:Humans; D008954:Models, Biological; D009543:Nifedipine / Q000378:metabolism*; D010089:Oxidoreductases, N-Demethylating / Q000502:physiology*; D013552:Swine; D013556:Swine, Miniature; D013739:Testosterone / Q000378:metabolism*
D013739:Testosterone; D019392:Cytochrome P-450 CYP2E1; D001189:Aryl Hydrocarbon Hydroxylases; D051544:Cytochrome P-450 CYP3A; D010089:Oxidoreductases, N-Demethylating; D009543:Nifedipine