Collagenous gastritis in a Korean child: a case report.
Collagenous gastritis, a counterpart of collagenous colitis, is an extremely rare disorder. The first case of collagenous gastritis in a Korean boy in his pre-teens who had been receiving treatment for refractory iron deficiency anemia has been reported. The patient had been suffering from intermittent abdominal pain, recurrent blood-tinged vomiting and poor oral intake. The gastric endoscopy revealed diffuse cobblestone appearance of the mucosa with easy touch bleeding throughout the stomach but no abnormalities in the esophagus, duodenum, and colon. Pathologic examination of the gastric biopsies from the antrum, body and cardia showed a subepithelial collagen deposition with entrapped dilated capillaries, moderate infiltrates of lympho-plasma cells and eosinophils of the lamina propria, and marked hypertrophy of the muscularis mucosa. The collagen deposition appeared as discontinuous bands with focally irregular extension into the deeper part of the antral mucosa. It measured up to 150 microm. Helicobacter pylori infection was not detected. The biopsies from the duodenum, esophagus and colon revealed no pathologic abnormalities.
Park
Sanghui
S
Departments of Pathology, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul, Korea.
Kim
Dong Hoon
DH
Choe
Youn Ho
YH
Suh
Yeon-Lim
YL
D001706:Biopsy; D002648:Child; D003092:Colitis / Q000175:diagnosis* / Q000473:pathology; D003094:Collagen / Q000378:metabolism; D004724:Endoscopy; D005753:Gastric Mucosa / Q000473:pathology; D005756:Gastritis / Q000473:pathology; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis / Q000473:pathology; D016480:Helicobacter pylori / Q000378:metabolism; D006801:Humans; D007723:Korea; D008297:Male; D009092:Mucous Membrane / Q000473:pathology; D013272:Stomach Diseases / Q000175:diagnosis / Q000473:pathology
D003094:Collagen
Mod Pathol. 2000 May;13(5):591-6
10824933
Scand J Gastroenterol. 1999 Jun;34(6):632-8
10440616
Arch Pathol Lab Med. 2001 Dec;125(12):1579-84
11735694
Pathol Int. 2003 Mar;53(3):174-8
12608899
Postgrad Med J. 1982 Jun;58(680):390-5
7122380
Gastroenterology. 1984 Sep;87(3):703-9
6378713
Gut. 1984 Oct;25(10):1085-8
6479682
Gut. 1986 May;27(5):570-7
3699567
Gastroenterology. 1986 Dec;91(6):1583-4
3770384
Ann Intern Med. 1987 Jan;106(1):108-13
3538963
Virchows Arch A Pathol Anat Histopathol. 1988;413(4):287-96
3140474
J Clin Gastroenterol. 1988 Dec;10(6):672-5
3230281
Dtsch Med Wochenschr. 1989 Sep 1;114(35):1345
2766959
Gastroenterology. 1989 Dec;97(6):1552-5
2583419
Endoscopy. 1990 Jul;22(4):186-7
2209504
J Clin Gastroenterol. 1996 Mar;22(2):134-7
8742654
Histopathology. 1996 Aug;29(2):101-10
8872143
Hum Pathol. 1998 Aug;29(8):883-6
9712433
Gut. 1999 Jun;44(6):881-5
10323893
Am J Surg Pathol. 2001 Sep;25(9):1174-9
11688577