title: [The development of osteosarcoma following radiotherapy for fibrous dysplasia].
abstract: Sarcoma arising from fibrous dysplasia (FD) is rare and it is more common in polyostotic type. In this case report, we present a 41-year-old male patient who developed osteosarcoma of the left tibia 28 years after the initial diagnosis and 20 years after radiation therapy for FD. He underwent above-knee amputation, but died eight months after surgery. This case suggests that radiotherapy has no beneficial effect in the treatment of FD and that it may be associated with the development of sarcoma.
authors.affiliation: Department of Orthopedics and Traumatology (5. Ortopedi ve Travmatoloji Kliniği), Ankara Numune Training and Research Hospital, Ankara, Turkey. muraltay@yahoo.com
authors.forename: Murat
authors.initials: M
authors.lastname: Altay
authors.forename: Kenan
authors.initials: K
authors.lastname: Bayrakci
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Yildiz
authors.forename: Yener
authors.initials: Y
authors.lastname: Sağlik
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D003937:Diagnosis, Differential; D005357:Fibrous Dysplasia of Bone / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D012516:Osteosarcoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D011859:Radiography; D011878:Radiotherapy / Q000009:adverse effects; D013977:Tibia