title: Protein structure topological comparison, discovery and matching service.
abstract: We describe a fold level fast protein comparison and motif matching facility based on the TOPS representation of structure. This provides an update to a previous service at the EBI, with a better graph matching with faster results and visualization of both the structures being compared against and the common pattern of each with the target domain.
  
  
  BACKGROUND
  Web service at http://balabio.dcs.gla.ac.uk/tops or via the main TOPS site at http://www.tops.leeds.ac.uk. Software is also available for download from these sites.
authors.affiliation: Bioinformatics Research Centre, Department of Computer Science, University of Glasgow, Glasgow G12 8QQ, UK.
authors.forename: G M
authors.initials: GM
authors.lastname: Torrance
authors.forename: D R
authors.initials: DR
authors.lastname: Gilbert
authors.forename: I
authors.initials: I
authors.lastname: Michalopoulos
authors.forename: D W
authors.initials: DW
authors.lastname: Westhead
mesh_terms: D000465:Algorithms; D003196:Computer Graphics; D003198:Computer Simulation; D020407:Internet; D008956:Models, Chemical; D008958:Models, Molecular; D011487:Protein Conformation; D017510:Protein Folding; D011506:Proteins / Q000032:analysis / Q000737:chemistry*; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software; D014584:User-Computer Interface
chemical_list: D011506:Proteins