title: A new pinoresinol-type lignan from Ligularia kanaitizensis.
abstract: A new pinoresinol-type Lignan, 9alpha-angloyloxypinoresinol (1), was isolated from the roots and rhizomes of Ligularia kanaitizensis (Franch.) Hand.-Mazz, in addition to a known compound, 9alpha-hydroxypinoresinol (2). The structure of this new lignan (1) was established on the basis of 1D and 2D NMR experiments. Anti-HIV-1 RT biological assay showed that 1 was inhibitory to HIV-1 RT.
authors.affiliation: Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, PR China. sinodlsia@yahoo.com
authors.forename: Yun-Sen
authors.initials: YS
authors.lastname: Li
authors.forename: Zheng-Tao
authors.initials: ZT
authors.lastname: Wang
authors.forename: Main
authors.initials: M
authors.lastname: Zhang
authors.forename: Shi-De
authors.initials: SD
authors.lastname: Luo
authors.forename: Ji-Jun
authors.initials: JJ
authors.lastname: Chen
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D054303:HIV Reverse Transcriptase / Q000037:antagonists & inhibitors; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy
chemical_list: C497301:9alpha-angloyloxypinoresinol; D005663:Furans; D017705:Lignans; D054303:HIV Reverse Transcriptase