title: [Intrathecal baclofen and Botulinum toxin in infantile cerebral palsy].
abstract: BACKGROUND
  Infantile cerebral palsy is considered to be a motor disorder affecting both posture and movement. It is the manifestation of a cerebral lesion that took place during the maturing process of the brain. Spastic cerebral palsy is the most frequent variety. The spasticity presented by these patients strongly influences their functioning and gives rise to several complications that affect their quality of life.
  
  
  OBJECTIVE
  The main aim of this study is to determine a set of suitable and effective therapeutic steps that can be used to improve patients' spasticity and to prevent the complications that stem from them, such as contractures, deformities, surgery, etc. Multiple treatments were used, including physiotherapy, rehabilitation and oral pharmacotherapy, with few satisfactory results. At present there are two very promising therapeutic alternatives for patients with infantile cerebral palsy: Botulinum toxin, which we already have a great deal of experience with, and intrathecal treatment with baclofen. We report on a series of 10 patients aged between 8 and 15 years who had had an intrathecal baclofen infusion pump implanted. To date (maximum follow-up: 12 months), their clinical course has been satisfactory in most cases, with no severe complications related to the surgical technique, except in one individual who presented a fistula that resolved spontaneously.
  
  
  CONCLUSIONS
  Intrathecal baclofen seems to be a very useful alternative in the treatment of spasticity to improve the quality of life of these patients and those around them.
authors.affiliation: Hospital Universitario La Fe, 46009 Valencia, Espana.
authors.forename: M
authors.initials: M
authors.lastname: Téllez de Meneses
authors.forename: P
authors.initials: P
authors.lastname: Barbero
authors.forename: J A
authors.initials: JA
authors.lastname: Alvarez-Garijo
authors.forename: F
authors.initials: F
authors.lastname: Mulas
mesh_terms: D001418:Baclofen / Q000008:administration & dosage*; D002547:Cerebral Palsy / Q000188:drug therapy*
chemical_list: D001418:Baclofen