title: Validity of sleep nasendoscopy in the investigation of sleep related breathing disorders.
abstract: OBJECTIVE
  To validate the technique of sleep nasendoscopy using target controlled infusion in symptomatic patients and a control group of asymptomatic individuals.
  
  
  METHODS
  Prospective cohort study.
  
  
  METHODS
  Department of otolaryngology-head and neck surgery and anesthesia in a teaching hospital.
  
  
  METHODS
  Two groups of patients were compared and matched for their body mass index. The first group consisted of 53 patients with a history suggestive of obstructive sleep apnea. The second group consisted of 54 patients with partner-confirmed history of no snoring. These patients were undergoing anesthesia for other reasons. Both groups of patients were free of associated otorhinolaryngologic symptoms.
  
  
  METHODS
  Assessment of production of snoring or obstruction in patients with no documented history of snoring when sedation was administered as part of general anesthesia using target controlled infusion with propofol.
  
  
  CONCLUSIONS
  None of the patients in the asymptomatic group snored or obstructed at any level of propofol, and this was clearly significant on comparison with the symptomatic group (P < .001). All of the symptomatic patients were induced to become symptomatic (snoring/obstruction).
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Singleton Hospital, Swansea, UK.
authors.forename: S
authors.initials: S
authors.lastname: Berry
authors.forename: G
authors.initials: G
authors.lastname: Roblin
authors.forename: A
authors.initials: A
authors.lastname: Williams
authors.forename: A
authors.initials: A
authors.lastname: Watkins
authors.forename: H B
authors.initials: HB
authors.lastname: Whittet
mesh_terms: D015992:Body Mass Index; D016022:Case-Control Studies; D004724:Endoscopy; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009666:Nose; D015742:Propofol / Q000008:administration & dosage; D011446:Prospective Studies; D015203:Reproducibility of Results; D012890:Sleep / Q000502:physiology; D012891:Sleep Apnea Syndromes / Q000175:diagnosis* / Q000503:physiopathology; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis / Q000503:physiopathology; D012913:Snoring / Q000503:physiopathology
chemical_list: D006993:Hypnotics and Sedatives; D015742:Propofol