Evaluation of the estrogenic activity of Leguminosae plants.
The plant extracts of the Leguminosae family were screened for their estrogenic activity with the Ishikawa cell system. Of the tested plants, Desmodium oxyphyllum, Dunbaria villosa, Kummerowia striata, Lespedeza bicolor, Maackia amurensis, Maackia fauriei, Pueraria thunbergiana, and Sophora flavescens were highly estrogenic with EC50 values of less than 10 microg/ml.
Yoo
Hye Hyun
HH
College of Pharmacy, Seoul National University, Seoul, Korea.
Kim
Taehyeong
T
Ahn
Soyun
S
Kim
Yoon Jung
YJ
Kim
Hyun Young
HY
Piao
Xiang Lan
XL
Park
Jeong Hill
JH
D045744:Cell Line, Tumor; D004353:Drug Evaluation, Preclinical / Q000379:methods; D007887:Fabaceae; D006801:Humans; D048789:Phytoestrogens / Q000302:isolation & purification / Q000494:pharmacology* / Q000633:toxicity; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology
D048789:Phytoestrogens; D010936:Plant Extracts