Promotion of oxygen atom transfer in Mo and W enzymes by bicyclic forms of the pterin cofactor.
Density functional theory calculations suggest that bicyclic structures of the "molybdopterin" in DMSO reductases may have an important catalytic role in oxygen atom transfer reactions.
McNamara
Jonathan P
JP
School of Chemistry, University of Manchester, Manchester, UK M13 9PL.
Joule
John A
JA
Hillier
Ian H
IH
Garner
C David
CD
D003067:Coenzymes / Q000737:chemistry* / Q000378:metabolism; D004798:Enzymes / Q000737:chemistry* / Q000378:metabolism*; D015394:Molecular Structure; D008982:Molybdenum / Q000378:metabolism*; D010100:Oxygen / Q000737:chemistry* / Q000378:metabolism; D011622:Pterins / Q000737:chemistry* / Q000378:metabolism; D014414:Tungsten / Q000378:metabolism*
D003067:Coenzymes; D004798:Enzymes; D011622:Pterins; D008982:Molybdenum; D010100:Oxygen; D014414:Tungsten