Cadherins and catenins in synapse development.
Cadherin-catenin complexes have been well established as key regulators of cell adhesion. Recent work has elucidated a pivotal role for these molecules in synaptic assembly, remodelling and plasticity. Far from being mere adhesive scaffolds, cadherins might directly regulate cell signalling to modulate synaptic connectivity.
Salinas
Patricia C
PC
Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom. p.salinas@ucl.ac.uk
Price
Stephen R
SR
D000818:Animals; D015820:Cadherins / Q000502:physiology*; D003598:Cytoskeletal Proteins / Q000502:physiology*; D006801:Humans; D008959:Models, Neurological; D013569:Synapses / Q000502:physiology*
D015820:Cadherins; D003598:Cytoskeletal Proteins