title: VEMP recording by binaural simultaneous stimulation in subjects with vestibulo-cochlear disorders.
abstract: To reduce the testing time of vestibular evoked myogenic potentials (VEMP) and the physical efforts of subjects, we studied if VEMP recording by binaural simultaneous stimulation in patients with vestibulo-cochlear disorders can be applicable as a screening test. Twenty-eight patients with vestibulo-cochlear disorders (12 men and 16 women, 22 to 77 years of age) were enrolled in this study. Patients were presented with binaural or monaural click (95 dBnHL) stimulation to record VEMPs. Their VEMP responses to binaural simultaneous stimulation were compared with those of monaural individual stimulation. Twenty-six of the 28 patients (93%) showed the same results in binaural simultaneous stimulation as in monaural individual stimulation. Amplitudes of p13-n23 to binaural simultaneous stimulation showed significant correlation to those of monaural individual stimulation ( r =0.774, P <0.0001 t -test). Peak latencies of p13 and n23 of binaural simultaneous stimulation also showed significant correlation to those of monaural individual stimulation (p13: r =0.684, P <0.0001 t -test, n23: r =0.657, P <0.0001 t -test). The binaural simultaneous stimulation method for VEMP recording is applicable for patients with vestibulo-cochlear disorders as a screening test in the clinic.
authors.affiliation: Department of Otolaryngology, Tokyo Postal Services Agency Hospital, 2-14-23 Fujimi Chiyoda-ku, 102-8798, Tokyo, Japan. toshi-tky@umin.ac.jp
authors.forename: Toshihisa
authors.initials: T
authors.lastname: Murofushi
authors.forename: Yoshinari
authors.initials: Y
authors.lastname: Takai
authors.forename: Shinichi
authors.initials: S
authors.lastname: Iwasaki
authors.forename: Masaki
authors.initials: M
authors.lastname: Matsuzaki
mesh_terms: D000328:Adult; D000368:Aged; D004576:Electromyography; D019054:Evoked Potentials, Motor / Q000502:physiology; D005260:Female; D006801:Humans; D007759:Labyrinth Diseases / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D014724:Vestibular Function Tests / Q000379:methods*; D014722:Vestibule, Labyrinth / Q000502:physiology*
references.citation: J Neurol Neurosurg Psychiatry. 1994 Feb;57(2):190-7
references.pmid: 8126503
references.citation: Arch Otolaryngol Head Neck Surg. 1996 Aug;122(8):845-8
references.pmid: 8703387
references.citation: Int J Audiol. 2004 Feb;43(2):66-8
references.pmid: 15035558
references.citation: Scand Audiol. 2001;30(3):189-96
references.pmid: 11683457
references.citation: Exp Brain Res. 1999 Jun;126(3):410-6
references.pmid: 10382625
references.citation: Hear Res. 2003 Nov;185(1-2):43-8
references.pmid: 14599691