title: Cancer of the uterine corpus among Hispanic women living in the United States: patterns of staging, diagnosis, and primary treatment.
abstract: OBJECTIVE
  To evaluate the demographic characteristics, clinico-pathological features, and patterns of care of uterine cancer among Hispanic women living in the United States.
  
  
  METHODS
  The National Cancer Institute (NCI)'s Surveillance, Epidemiology, and End Results Program (SEER), was used to identify 1618 Hispanic, 17,814 non-Hispanic white (NHW), and 1477 non-Hispanic black (NHB) women diagnosed with primary carcinoma of the uterus during 1996-2000. Data derived from hospital registries was analyzed, for differences in case presentation, staging, and primary treatment by race/ethnicity and age. Statistical analysis was performed using the IBM PC packages, Stata, and the SAS system.
  
  
  RESULTS
  Hispanic women were statistically significantly more likely to present with uterine cancer at a younger age compared to non-Hispanic groups. Hispanic women with early stage disease (stage I-II) were also statistically significantly more likely to be younger than 55 years at the time of diagnosis (NHW: OR=0.40, 95% CI: 0.35-0.45; P = 0.0000, NHB: OR=0.45, 95% CI: 0.38-0.55; P=0.0000). Hispanics were statistically significant less likely than NHB to present with advanced stage disease, high tumor grade, and receive radiation therapy for uterine cancer.
  
  
  CONCLUSIONS
  Hispanic women are more likely to be diagnosed with uterine cancer at a younger age than other ethnic groups. The etiologic factors related to this presentation have yet to be precisely defined. Additional epidemiological and demographic studies, addressing such factors as body mass index and other medical co-morbidities, are needed to identify opportunities for improved cancer prevention and control in this population of women.
authors.affiliation: The Kelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics, The Johns Hopkins Medical Institutions, 600 North Wolfe Street, Phipps #281, Baltimore, MD 21287, USA. tdiazmo1@jhmi.edu
authors.forename: Teresa P
authors.initials: TP
authors.lastname: Díaz-Montes
authors.forename: Anthony
authors.initials: A
authors.lastname: Alberg
authors.forename: Mariana L
authors.initials: ML
authors.lastname: Zahurak
authors.forename: Edward L
authors.initials: EL
authors.lastname: Trimble
authors.forename: Robert E
authors.initials: RE
authors.lastname: Bristow
mesh_terms: D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D018426:SEER Program; D014481:United States / Q000453:epidemiology; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000208:ethnology* / Q000628:therapy