title: [History of the rhenish and alsacian contributions to the understanding of diabetes].
abstract: The history of diabetes mellitus is punctuated from the Egyptian Antiquity by sometimes amazingly acute clinical observations and inversely several missed opportunities on the way of the discovery of the mechanisms of the disease and of the development of its therapies.Alsace, and more generally the Rhine countries, have played a major role in this adventure, of which a crucial step has been the experimental demonstration of the role of the pancrease in the pathogenis of the disease by Oskar Minkowski and Joseph von Mering in Strasbourg in 1889.
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Brogard
authors.forename: Jean-Frédéric
authors.initials: JF
authors.lastname: Blickle
mesh_terms: D001680:Biographies as Topic; D003920:Diabetes Mellitus / Q000266:history*; D005602:France; D005858:Germany; D049668:History, 15th Century; D049669:History, 16th Century; D049670:History, 17th Century; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D013557:Switzerland