Symptomatic focal mononeuropathies in diabetic patients: increased or not?
The aim of this study was to investigate whether symptomatic mononeuropathies are more frequent in diabetic patients without symptoms of acute or subacute polyneuropathy than in the general population.For this purpose, six hundred and forty two consecutive outpatients with various acute symptomatic mononeuropathies (radial, ulnar or peroneal neuropathy, Bell's palsy or carpal tunnel syndrome) without symptoms of acute or subacute polyneuropathy were studied. The results showed that in 522 patients with symptomatic carpal tunnel syndrome (CTS) and in 38 patients with Bell's palsy, the rate of diabetes was 7.7% and 10.5%, respectively. These rates do not differ significantly from the anticipated frequency of diabetes in the general population. On the other hand, in 18 patients with radial neuropathy at (or distally to) the spiral groove, in 41 patients with ulnar neuropathy and in 23 patients with peroneal neuropathy at the fibular head, the respective rates were 27.8%, 12.2 % and 30.4%. These rates are significantly higher than those anticipated according to the frequency of diabetes in the general population. The findings of the present study indicate that only focal limb neuropathies due to acute external compression are more frequent in diabetic patients.
Stamboulis
Elefterios
E
Dept. of Neurology National and Kapodistrian University of Athens, Medical School, Eginition Hospital 74, Vas. Sophias Av. 11528 Athens, Greece.
Vassilopoulos
Demetris
D
Kalfakis
Nikolaos
N
D000200:Action Potentials / Q000502:physiology; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D048909:Diabetes Complications; D003929:Diabetic Neuropathies / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020422:Mononeuropathies / Q000453:epidemiology* / Q000209:etiology*; D018482:Muscle, Skeletal / Q000503:physiopathology; D009431:Neural Conduction / Q000502:physiology; D009483:Neuropsychological Tests
J Neurol Neurosurg Psychiatry. 1999 Sep;67(3):277-9
10449543
Muscle Nerve. 1993 Feb;16(2):127-34
8381517
Br Med J (Clin Res Ed). 1986 Oct 25;293(6554):1053-4
3094772
Neurology. 1993 Apr;43(4):817-24
8469345
J Neurol Neurosurg Psychiatry. 1962 Feb;25:11-8
13898654
Ann Intern Med. 1996 Jan 1;124(1 Pt 1):27-30
7503474
Muscle Nerve. 1996 Feb;19(2):140-6
8559161
Acta Neurol Scand. 1972;48(3):381-4
5055278
Adv Otorhinolaryngol. 1977;22:182-9
868700
Neurology. 1993 Nov;43(11):2406-9
8232968
Diabet Med. 1993 Jan-Feb;10(1):87-90
8435995
Lancet. 1971 Jul 17;2(7716):168
4104499
J Neurol Neurosurg Psychiatry. 1974 Mar;37(3):340-60
4829536
Electromyogr Clin Neurophysiol. 1987 Mar;27(2):119-23
3582257
Eur Neurol. 2000;44(1):1-7
10894988
Ann Neurol. 1980 Aug;8(2):168-78
7425570
Diabetes. 1990 Aug;39(8):909-13
2373263
J Neurol Neurosurg Psychiatry. 1982 Jul;45(7):652-5
7119834
Brain Res Bull. 1982 Mar;8(3):317-23
7093738
Electromyogr Clin Neurophysiol. 1988 Aug-Oct;28(6):301-6
3248552
Diabetologia. 1993 Dec;36(12 ):1266-74
8307254
Postgrad Med J. 1968 Feb;44(508):127-33
5650986
Lancet. 1971 Jan 16;1(7690):108-9
4099604
J Neurol Sci. 1981 Nov-Dec;52(2-3):289-303
7310436
Clin Orthop Relat Res. 1972 Mar-Apr;83:29-40
5014825
Ann Neurol. 1994 Sep;36(3):408-15
8080248
Electromyogr Clin Neurophysiol. 1986 Jun-Jul;26(4):283-95
3757897
J Neurol Sci. 1993 Nov;119(2):154-61
8277329
J Neurol Sci. 1999 Nov 15;170(1):19-23
10540031
Diabetologia. 1993 May;36(5):454-9
8314451
Am J Epidemiol. 1990 Dec;132(6):1102-10
2260542
Diabetologia. 1986 Mar;29(3):181-5
2422081
Diabetes. 1975 May;24(5):449-51
1126588
Neurology. 1992 Jun;42(6):1164-70
1603343
Neurology. 1961 Apr;11(4)Pt 1:275-84
13773672
Lancet. 1969 Nov 1;2(7627):930-1
4186597
Ann Neurol. 1984 Jan;15(1):2-12
6370098