title: Synthesis of substituted quinolines by electrophilic cyclization of N-(2-alkynyl)anilines.
abstract: Quinolines substituted in the 3-position by an iodo or phenylseleno group are readily prepared in good to excellent yields by the reaction of propargylic anilines with appropriate electrophiles under mild reaction conditions. [reaction: see text]
authors.affiliation: Department of Chemistry, Iowa State University, Ames, IA 50011, USA.
authors.forename: Xiaoxia
authors.initials: X
authors.lastname: Zhang
authors.forename: Marino A
authors.initials: MA
authors.lastname: Campo
authors.forename: Tuanli
authors.initials: T
authors.lastname: Yao
authors.forename: Richard C
authors.initials: RC
authors.lastname: Larock
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000814:Aniline Compounds / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D015394:Molecular Structure; D011804:Quinolines / Q000032:analysis / Q000138:chemical synthesis*
chemical_list: D000480:Alkynes; D000814:Aniline Compounds; D011804:Quinolines