title: Sexually transmitted infections in rural Madagascar at an early stage of the HIV epidemic: a 6-month community-based follow-up study.
abstract: OBJECTIVE
  Sexually transmitted infections (STIs) in Madagascar have primarily been monitored in selected groups of patients attending STI clinics in major cities as part of the HIV surveillance program in Madagascar.
  
  
  OBJECTIVE
  The aim of the study was to provide complementary data related to STI prevalence in a general rural population.
  
  
  METHODS
  STIs were investigated in 643 subjects aged 15 to 49 years as part of a cross-sectional morbidity study of urogenital schistosomiasis. Infection rates were reassessed 3 weeks and 6 months after systematic STI treatment at baseline.
  
  
  RESULTS
  Neisseria gonorrhoeae (Ng), Chlamydia trachomatis (Ct), Mycoplasma genitalium (Mg), Trichomonas vaginalis (Tv), and/or antibodies to Treponema pallidum (Tp) were diagnosed in 125 (37.5%) of 333 women and in 83 (26.8%) of 310 men. In addition, 49% of the women and 28% of the men were infected with herpes simplex virus-2. Six (0.9%) subjects were found HIV-antibody positive. Between the 3-week and 6-month follow-up surveys Ng, Ct, and/or Mg prevalence increased most prominently in women aged 15 to 24 years.
  
  
  CONCLUSIONS
  Study findings suggest that rural areas in Madagascar should be as closely monitored and assisted in STI and HIV control as their urban counterparts. Following the current consensus, young adults should constitute a priority target group in the control programs.
authors.affiliation: Institut Pasteur de Madagascar, Antananarivo, Madagascar. pl@bilharziasis.dk
authors.forename: Peter
authors.initials: P
authors.lastname: Leutscher
authors.forename: Jorgen Skov
authors.initials: JS
authors.lastname: Jensen
authors.forename: Steen
authors.initials: S
authors.lastname: Hoffmann
authors.forename: Lene
authors.initials: L
authors.lastname: Berthelsen
authors.forename: Charles-Emile
authors.initials: CE
authors.lastname: Ramarakoto
authors.forename: Vero
authors.initials: V
authors.lastname: Ramaniraka
authors.forename: Bodo
authors.initials: B
authors.lastname: Randrianasolo
authors.forename: Clairette
authors.initials: C
authors.lastname: Raharisolo
authors.forename: Blenda
authors.initials: B
authors.lastname: Böttiger
authors.forename: Dominique
authors.initials: D
authors.lastname: Rousset
authors.forename: Pierre
authors.initials: P
authors.lastname: Grosjean
authors.forename: Moriah McSharry
authors.initials: MM
authors.lastname: McGrath
authors.forename: Niels
authors.initials: N
authors.lastname: Christensen
authors.forename: Rene
authors.initials: R
authors.lastname: Migliani
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D004196:Disease Outbreaks; D005260:Female; D015658:HIV Infections / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D008270:Madagascar / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012423:Rural Health; D017678:Sex Distribution; D012749:Sexually Transmitted Diseases / Q000453:epidemiology* / Q000209:etiology; D012959:Socioeconomic Factors