title: Analgesic activity of enkephalins following intracerebral administration in the rat.
authors.affiliation: Biomedical Research Department, Stuart Pharmaceuticals, Division of ICI United States Inc., Wilmington, DE 19897, USA.
authors.forename: J B
authors.initials: JB
authors.lastname: Malick
authors.forename: J M
authors.initials: JM
authors.lastname: Goldstein
mesh_terms: D000700:Analgesics / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004336:Drug Antagonism; D004743:Enkephalin, Leucine / Q000008:administration & dosage / Q000494:pharmacology*; D004744:Enkephalin, Methionine / Q000008:administration & dosage / Q000494:pharmacology*; D007276:Injections, Intraventricular; D008297:Male; D009020:Morphine / Q000494:pharmacology; D009270:Naloxone / Q000494:pharmacology; D009292:Narcotic Antagonists / Q000494:pharmacology; D010146:Pain / Q000517:prevention & control*; D010147:Pain Measurement; D017288:Pain Threshold / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D013623:Tail
chemical_list: D000700:Analgesics; D009292:Narcotic Antagonists; D009270:Naloxone; D004744:Enkephalin, Methionine; D004743:Enkephalin, Leucine; D009020:Morphine