Gastric schwannoma.
Gastrointestinal mesenchymal tumors are a group of tumors originated from the mesenchymal stem cells of the gastrointestinal tract, consisting of gastrointestinal stromal tumors (GIST), leiomyomas or leiomyosarcomas or schwannomas. Gastric schwannoma is a very rare gastrointestinal mesenchymal tumor, which represents only 0.2% of all gastric tumors and 4% of all benign gastric neoplasms. We report a 24-year-old girl who suffered from an episode of upper gastrointestinal bleeding. The endoscopic examination showed a round submucosal tumor with a central ulceration and bleeding over the high body of the stomach. Surgical resection of the tumor was performed. The pathological examination revealed a picture of spindle cell tumor that was strongly positive for S-100 protein stain, and non-reactive for CD34, CD117, actin, HHF-35, desmin, melan-A and HMB-45, consistent with gastric schwannoma. The literature is reviewed.
Lin
Chen-Sung
CS
Taipei Veterans General Hospital, Taiwan.
Hsu
Han-Shui
HS
Tsai
Chien-Ho
CH
Li
Wing-Yin
WY
Huang
Min-Hsiung
MH
D000328:Adult; D020776:Endoscopes, Gastrointestinal; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D009442:Neurilemmoma / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D009418:S100 Proteins / Q000032:analysis; D013270:Stomach / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology; D013274:Stomach Neoplasms / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D013276:Stomach Ulcer / Q000150:complications; D014057:Tomography, X-Ray Computed
D009418:S100 Proteins