Solar urticaria and porphyrias.
The importance of disturbances of porphyrin metabolism in solar urticaria is discussed. 15 cases of porphyrias with sun sensitivity are presented comprising 5 cases of erythropoietic protoporhyria, 8 cases of coproporphyria hereditaria and 2 cases of porphyria variegata, 9 out of these 10 patients presented neuroabdominal symptoms and in 4 cases contraceptive pills have triggered the disease. Due to the risk of severe forms of disease sometimes drugs induced porphyrias must be considered in all cases of solar urticaria and a correct laboratory study done in the suspected cases.
Palma-Carlos
A G
AG
Immunoallergology Department, Santa Maria Hospital, Lisbon, Portugal.
Palma-Carlos
M L
ML
D015746:Abdominal Pain / Q000209:etiology; D001247:Asthenia / Q000209:etiology; D003270:Contraceptive Agents / Q000009:adverse effects; D046349:Coproporphyria, Hereditary / Q000150:complications; D003306:Coproporphyrins / Q000652:urine; D017454:Dermatitis, Photoallergic / Q000209:etiology*; D004967:Estrogens / Q000009:adverse effects; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D007813:Laparotomy; D008297:Male; D017092:Porphyria, Erythropoietic / Q000150:complications; D046350:Porphyria, Variegate / Q000150:complications; D011164:Porphyrias / Q000150:complications*; D011524:Protoporphyrins / Q000097:blood / Q000652:urine; D012997:Solvents / Q000009:adverse effects; D013472:Sunlight / Q000009:adverse effects*; D019564:Unnecessary Procedures; D014578:Uroporphyrins / Q000652:urine; D014581:Urticaria / Q000209:etiology*
D003270:Contraceptive Agents; D003306:Coproporphyrins; D004967:Estrogens; D011524:Protoporphyrins; D012997:Solvents; D014578:Uroporphyrins; D007073:Immunoglobulin E