Focus on recent approaches for the development of new NO-donors.
Recent research developments in the field of NO-donor compounds have concerned conjugation of NO-donor moieties with antioxidant groups, NO-donor targeting, design of NO-donor hybrid drugs and of NO-delivery systems. These new approaches are illustrated and discussed through selected examples.
Gasco
A
A
Dipartimento di Scienza e Tecnologia del Farmaco, Via Pietro Giuria 9, 10125 Torino, Italy. alberto.gasco@unito.it
Fruttero
R
R
Rolando
B
B
D000818:Animals; D000975:Antioxidants / Q000737:chemistry; D016503:Drug Delivery Systems; D015195:Drug Design; D006801:Humans; D020030:Nitric Oxide Donors / Q000737:chemistry / Q000494:pharmacology*
D000975:Antioxidants; D020030:Nitric Oxide Donors