Disposition of cisapride appears to be influenced by P-glycoprotein in the mouse.
Choo
Edna F
EF
Venkatakrishnan
Karthik
K
Hatch
Heather L
HL
Rahematpura
Sandhya
S
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D000284:Administration, Oral; D000818:Animals; D019540:Area Under Curve; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D020117:Cisapride / Q000378:metabolism* / Q000494:pharmacology; D006801:Humans; D051379:Mice; D018345:Mice, Knockout; D011358:Product Surveillance, Postmarketing; D014018:Tissue Distribution / Q000187:drug effects
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D020117:Cisapride