Biotransformation of alpha-bulnesene using a plant pathogenic fungus, Glomerella cingulata as a biocatalyst.
The biotransformation of a sesquiterpene having a guaiane skeleton, namely (+)-alpha-bulnesene was investigated using the plant pathogenic fungus, Glomerella cingulata as a biocatalyst. (+)-alpha-Bulnesene was oxidized at the double bond of the isopropenyl group and hydroxylated at the allylic methyl group to (4S,5S,7R)-1(10)-guaien-11,13,15-triol.
Miyazawa
Mitsuo
M
Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Kowakae, Higashiosakashi, Osaka, Japan. miyazawa@apch.kindai.ac.jp
Sugawara
Atsushi
A
D001711:Biotransformation; D009682:Magnetic Resonance Spectroscopy; D020081:Phyllachorales / Q000378:metabolism*; D012717:Sesquiterpenes / Q000378:metabolism*
D012717:Sesquiterpenes