Ruthenium-catalyzed coupling of aldimines with arylboronates: new synthetic method for aromatic ketones.
Using the chelation strategy, the reaction of aldimines bearing the 3-picolin-2-yl group with various arylboronates in the presence of a ruthenium catalyst furnished the corresponding ketimines in high yields for a short reaction time; the resulting ketimines were readily converted to ketones by hydrolysis.
Park
Young Jun
YJ
Department of Chemistry and Center for Bioactive Molecular Hybrid (CBMH), Yonsei University, Seoul 120-749, Korea.
Jo
Eun-Ae
EA
Jun
Chul-Ho
CH
D000588:Amines / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry; D002384:Catalysis; D006868:Hydrolysis; D007659:Ketones / Q000138:chemical synthesis*; D015394:Molecular Structure; D012428:Ruthenium / Q000737:chemistry*
D000588:Amines; D001897:Boronic Acids; D007659:Ketones; D012428:Ruthenium