[Exploring relationship between traditional effects of traditional Chinese medicine and modern pharmacological activities by "co-effect compounds"].
The compound that distributes in the herbs with one common effect was named as "co-effect compound" (CEC). The CECs of three traditional Chinese medicine(TCM) effects, purgative, relieving pain and clearing heat, had been found and studied. A strong corresponding relationship was found between the pharmacological activities of CECs and the TCM effect they belong to. The study shows that it may be a feasible method to connect traditional effect of TCM with modem pharmacological activity.
Liu
Hai-Bo
HB
Lu
Ai-Jun
AJ
Liu
Bing
B
Zhou
Jia-Ju
JJ
D000880:Anthraquinones / Q000302:isolation & purification / Q000494:pharmacology*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D002400:Cathartics / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology; D008516:Medicine, Chinese Traditional; D010946:Plants, Medicinal / Q000737:chemistry
D000880:Anthraquinones; D000894:Anti-Inflammatory Agents, Non-Steroidal; D002400:Cathartics; D004365:Drugs, Chinese Herbal; D005419:Flavonoids