Bilateral subthalamic nucleus stimulation improves health-related quality of life in Parkinsonian patients.
Parkinson's disease (PD) is a common neurological disorder. Recently, bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become an option in the treatment of severe PD. We measured the health-related quality of life (HRQoL) of 27 parkinsonian patients, who underwent a bilateral STN-operation. The instruments used for the evaluation of the HRQoL were the Parkinson's Disease Questionnaire (PDQ-39) and the Finnish version of the Nottingham Health Profile (NHP). We found that the quality of life significantly improved when measured with both HRQoL scales. Clinical improvement and improvement in HRQoL were positively correlated.
Erola
Tuomo
T
Department of Neurosurgery, Oulu University Hospital, P.O. Box 21, FIN-90029 Oys, Finland. tuomo.erola@pp.inet.fi
Karinen
Petri
P
Heikkinen
Esa
E
Tuominen
Juho
J
Haapaniemi
Tarja
T
Koivukangas
John
J
Myllylä
Vilho
V
D000368:Aged; D046690:Deep Brain Stimulation / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D007839:Functional Laterality; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000523:psychology* / Q000628:therapy*; D011788:Quality of Life; D020531:Subthalamic Nucleus / Q000502:physiology*; D011795:Surveys and Questionnaires