title: Management of portal hypertension.
abstract: Complications of portal hypertension are the leading cause of death in patients with liver cirrhosis. Rational medical and endoscopic therapy is guided by a thorough understanding of the underlying pathophysiology of ascites, variceal formation and bleeding, hepatorenal syndrome, and hepatic encephalopathy. The pathophysiology of each clinical entity is reviewed followed by an evidence-based diagnostic and management algorithm.
authors.affiliation: Department of Medicine, Division of Gastroenterology/KIM 1, Martin-Luther University Halle-Wittenberg, Ernst-Grube Strasse 40, D-06097 Halle (Saale), Germany. hubert.nietsch@medizin.uni-halle.de
authors.forename: Hubert H
authors.initials: HH
authors.lastname: Nietsch
mesh_terms: D000208:Acute Disease; D001201:Ascites / Q000209:etiology; D006501:Hepatic Encephalopathy / Q000209:etiology; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications / Q000628:therapy