title: Influenza, autoimmunity and atherogenesis.
abstract: It has been observed during influenza epidemics and in a number of population and clinical trials that this prevalent viral infection was associated with increased death rates from cardiovascular diseases. The clinical and experimental data that may explain accelerated coronary atherosclerosis in influenza infection with implications involving autoimmune mechanisms are reviewed in this article. Both cellular and humoral autoimmune mode could be proposed to participate in the onset or progression of atheromatous lesions due to influenza infection.
authors.affiliation: Mechnicov's State Medical Academy, The Center of Atherosclerosis and Lipid Disorders, Chair of Cardiology, 194291 pr. Kultury 4, CMSD-122, Saint Petersburg, Russia. Gur@cards.lanck.net
authors.forename: Victor S
authors.initials: VS
authors.lastname: Gurevich
mesh_terms: D000818:Animals; D001323:Autoantibodies / Q000276:immunology; D015551:Autoimmunity; D003324:Coronary Artery Disease / Q000209:etiology* / Q000276:immunology; D006801:Humans; D007252:Influenza Vaccines / Q000008:administration & dosage; D007251:Influenza, Human / Q000150:complications* / Q000517:prevention & control; D015227:Lipid Peroxidation; D008077:Lipoproteins, LDL / Q000276:immunology; D018716:Molecular Mimicry
chemical_list: D001323:Autoantibodies; D007252:Influenza Vaccines; D008077:Lipoproteins, LDL