title: Ecotoxicological effects of selected cyanobacterial secondary metabolites: a short review.
abstract: Cyanobacteria are one of the most diverse groups of gram-negative photosynthetic prokaryotes. Many of them are able to produce a wide range of toxic secondary metabolites. These cyanobacterial toxins can be classified in five different groups: hepatotoxins, neurotoxins, cytotoxins, dermatotoxins, and irritant toxins (lipopolysaccharides). Cyanobacterial blooms are hazardous due to this production of secondary metabolites and endotoxins, which could be toxic to animals and plants. Many of the freshwater cyanobacterial blooms include species of the toxigenic genera Microcystis, Anabaena, or Plankthotrix. These compounds differ in mechanisms of uptake, affected organs, and molecular mode of action. In this review, the main focus is the aquatic environment and the effects of these toxins to the organisms living there. Some basic toxic mechanisms will be discussed in comparison to the mammalian system.
authors.affiliation: Leibniz Institute of Freshwater Ecology and Inland Fisheries, Müggelseedamm 301, 12587 Berlin, Germany. cwiegand@igb-berlin.de
authors.forename: C
authors.initials: C
authors.lastname: Wiegand
authors.forename: S
authors.initials: S
authors.lastname: Pflugmacher
mesh_terms: D000818:Animals; D001427:Bacterial Toxins / Q000737:chemistry / Q000378:metabolism* / Q000633:toxicity*; D000458:Cyanobacteria / Q000378:metabolism*; D000087522:Cyanobacteria Toxins; D017753:Ecosystem; D004781:Environmental Exposure / Q000009:adverse effects; D006801:Humans; D008387:Marine Toxins / Q000737:chemistry / Q000378:metabolism* / Q000633:toxicity*; D052998:Microcystins
chemical_list: D001427:Bacterial Toxins; D000087522:Cyanobacteria Toxins; D008387:Marine Toxins; D052998:Microcystins