title: Spontaneous multiple arterial dissections presenting with renal infarction and subarachnoid hemorrhage in a patient under treatment for infertility.
abstract: A 36-year-old woman developed multiple spontaneous arterial dissections in both renal arteries, the carotid artery, superior mesenteric artery, and vertebral artery, but not the aorta, and she suffered a renal infarction and subarachnoid hemorrhage within a short period of time. She had been undergoing frequent injections of human chorionic gonadotropin and human menopausal gonadotropin, together with oral estrogen therapy, during a 5-year infertility treatment regimen. As she had no other history of any disorder affecting the arterial walls, this therapy is suspected to have caused the multiple arterial deformities. Although cases of isolated arterial dissection are occasionally reported, it is rare for multiple dissections and serious symptoms to occur simultaneously.
authors.affiliation: Department of Internal Medicine, Hamamatsu Red Cross Hospital, Shizuoka, Japan. swakino@sc.itc.keio.ac.jp
authors.forename: Shu
authors.initials: S
authors.lastname: Wakino
authors.forename: Kei
authors.initials: K
authors.lastname: Tawarahara
authors.forename: Naoto
authors.initials: N
authors.lastname: Tsuchiya
authors.forename: Yoshitomo
authors.initials: Y
authors.lastname: Kurosawa
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Sugihara
authors.forename: Koushi
authors.initials: K
authors.lastname: Ando
mesh_terms: D000328:Adult; D000792:Angiography; D001158:Arteries / Q000293:injuries*; D005260:Female; D005300:Fertility Agents, Female / Q000009:adverse effects*; D006801:Humans; D007231:Infant, Newborn; D007238:Infarction / Q000139:chemically induced* / Q000175:diagnosis; D007668:Kidney / Q000098:blood supply; D007674:Kidney Diseases / Q000139:chemically induced / Q000175:diagnosis; D013345:Subarachnoid Hemorrhage / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D005300:Fertility Agents, Female