title: Antioxidative constituents of Etlingera elatior.
abstract: Phytochemical studies on the rhizomes of Etlingera elatior have resulted in the isolation of 1,7-bis(4-hydroxyphenyl)-2,4,6-heptatrienone (1), demethoxycurcumin (2), 1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one (3), 16-hydroxylabda-8(17),11,13-trien-15,16-olide (4), stigmast-4-en-3-one, stigmast-4-ene-3,6-dione, stigmast-4-en-6beta-ol-3-one, and 5alpha,8alpha-epidioxyergosta-6,22-dien-3beta-ol. Compounds 1 and 4 are new, and their structures were elucidated by analysis of spectroscopic data. Diarylheptanoids 1-3 were found to inhibit lipid peroxidation in a more potent manner than alpha-tocopherol.
authors.affiliation: Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
authors.forename: Habsah
authors.initials: H
authors.lastname: Mohamad
authors.forename: Nordin H
authors.initials: NH
authors.lastname: Lajis
authors.forename: Faridah
authors.initials: F
authors.lastname: Abas
authors.forename: Abdul Manaf
authors.initials: AM
authors.lastname: Ali
authors.forename: Mohamad Aspollah
authors.initials: MA
authors.lastname: Sukari
authors.forename: Hiroe
authors.initials: H
authors.lastname: Kikuzaki
authors.forename: Nobuji
authors.initials: N
authors.lastname: Nakatani
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D003474:Curcumin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D036381:Diarylheptanoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008296:Malaysia; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D030521:Zingiberaceae / Q000737:chemistry*
chemical_list: C499278:1,7-bis(4-hydroxyphenyl)-2,4,6-heptatrienone; C499279:16-hydroxylabda-8(17),11,13-trien-15,16-olide; D000975:Antioxidants; D036381:Diarylheptanoids; D004224:Diterpenes; D003474:Curcumin; C050229:demethoxycurcumin