title: Histology of hereditary neuralgic amyotrophy.
abstract: We report the findings in five muscle and three sural nerve biopsies, and in one postmortem plexus specimen, from six patients with hereditary neuralgic amyotrophy (HNA). We found that the sensory nerves are definitely involved in HNA despite the mainly motor symptoms, and that lesions in nerves and muscles are more widespread throughout the peripheral nervous system than clinically presumed, but, simultaneously, very focally affect isolated fascicles within individual nerves.
authors.affiliation: Neuromuscular Centre Nijmegen, Institute of Neurology, 314 University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands. n.vanalfen@neuro.umcn.nl
authors.forename: N
authors.initials: N
authors.lastname: van Alfen
authors.forename: A A W M
authors.initials: AA
authors.lastname: Gabreëls-Festen
authors.forename: H J
authors.initials: HJ
authors.lastname: Ter Laak
authors.forename: W F M
authors.initials: WF
authors.lastname: Arts
authors.forename: F J M
authors.initials: FJ
authors.lastname: Gabreëls
authors.forename: B G M
authors.initials: BG
authors.lastname: van Engelen
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D020516:Brachial Plexus Neuropathies / Q000473:pathology*; D002648:Child; D004247:DNA / Q000032:analysis; D004576:Electromyography; D005260:Female; D020271:Heredodegenerative Disorders, Nervous System / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology*; D013497:Sural Nerve / Q000473:pathology*
chemical_list: D004247:DNA