title: Periodontal disease and prematurity among non-smoking Sri Lankan women.
abstract: The hypothesis that periodontal disease is associated with pre-term low birthweight was tested in a prospective follow-up study of rural prima-gravida women (N = 227) who were free of tobacco, alcohol, and drug use. Women with 3rd trimester mean probing pocket depths, plaque, and bleeding scores that were greater than the median value in the cohort were defined as "exposed". There were 17 (7.5%) preterm low birthweight singleton deliveries in the cohort (among "exposed" = 12%; among "unexposed" = 5.6%; Odds Ratio = 2.3; 95% CI = 0.9-6.3). After adjustment for the independent variables, the OR for preterm low birthweight in relation to "exposure" was 1.9 (95% CI = 0.7-5.4). Our results are only suggestive of an association between periodontal disease and preterm low birthweight, perhaps indicating that previously reported associations may have been subjected to residual confounding due to tobacco, alcohol, and drug use.
authors.affiliation: Faculty of Dental Sciences, University of Peradeniya, Sri Lanka.
authors.forename: P S
authors.initials: PS
authors.lastname: Rajapakse
authors.forename: M
authors.initials: M
authors.lastname: Nagarathne
authors.forename: K B
authors.initials: KB
authors.lastname: Chandrasekra
authors.forename: A P
authors.initials: AP
authors.lastname: Dasanayake
mesh_terms: D000293:Adolescent; D000328:Adult; D015331:Cohort Studies; D015986:Confounding Factors, Epidemiologic; D003773:Dental Plaque / Q000150:complications; D005260:Female; D005500:Follow-Up Studies; D005884:Gingival Hemorrhage / Q000150:complications; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D010298:Parity; D010510:Periodontal Diseases / Q000150:complications*; D010514:Periodontal Pocket / Q000150:complications; D011247:Pregnancy; D011248:Pregnancy Complications; D011446:Prospective Studies; D012423:Rural Health; D013188:Sri Lanka