title: The surgical treatment of the lumbar disc prolapse: nucleotomy with additional transpedicular dynamic stabilization versus nucleotomy alone.
abstract: METHODS
  Clinical and radiologic study evaluating the outcome after nucleotomy with dynamic stabilization compared with nucleotomy alone.
  
  
  OBJECTIVE
  To investigate the effect of dynamic stabilization on the progression of segmental degeneration after nucleotomy.
  
  
  BACKGROUND
  Nucleotomy as treatment for lumbar disc prolapse in combination with initial segment degeneration may lead to segmental instability. Dynamic stabilization systems restrict segmental motion and thus prevent further degeneration of the lumbar spine. They are designed to avoid the disadvantages of rigid fixation, such as pseudarthrosis and adjacent segment degeneration.
  
  
  METHODS
  Eighty-four patients underwent nucleotomy of the lumbar spine for the treatment of symptomatic disc prolapse. Additional dynamic stabilization (DYNESYS) was performed in 35 of those cases. All patients showed signs of initial disc degeneration (MODIC I). They underwent evaluation before surgery, 3 months after surgery, and at follow-up. The mean duration of follow-up was 34 months. Examinations included radiographs, magnetic resonance imaging (MRI), physical examination, and subjective patient evaluation using Oswestry score and visual analog scale (VAS).
  
  
  RESULTS
  Clinical symptoms, Oswestry score, and VAS improved significantly in both groups after 3 months. At follow-up, a significant increase in the Oswestry score and in the VAS was seen only in the nonstabilized group. In the dynamically stabilized group, no progression of disc degeneration was noted at follow-up, whereas radiologic signs of accelerated segmental degeneration existed in the solely nucleotomized group. There were no implant-associated complications.
  
  
  CONCLUSIONS
  The applied dynamic stabilization system is useful to prevent progression of initial degenerative disc disease of lumbar spinal segments after nucleotomy.
authors.affiliation: Department of Orthopaedics, Center for Muskuloskeletal Surgery, Charité - University Medicine Berlin, Germany. michael.putzier@charite.de
authors.forename: Michael
authors.initials: M
authors.lastname: Putzier
authors.forename: Sascha V
authors.initials: SV
authors.lastname: Schneider
authors.forename: Julia F
authors.initials: JF
authors.lastname: Funk
authors.forename: Stephan W
authors.initials: SW
authors.lastname: Tohtz
authors.forename: Carsten
authors.initials: C
authors.lastname: Perka
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D017587:Diskectomy, Percutaneous / Q000379:methods / Q000706:statistics & numerical data*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007403:Intervertebral Disc / Q000000981:diagnostic imaging / Q000601:surgery; D007405:Intervertebral Disc Displacement / Q000000981:diagnostic imaging / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement / Q000706:statistics & numerical data; D011446:Prospective Studies; D011859:Radiography; D012189:Retrospective Studies; D013123:Spinal Fusion / Q000379:methods / Q000706:statistics & numerical data*