Swapping molecules during cell-cell interactions.
Interactions between cells of the immune system can lead to intercellular exchange of cell-surface molecules. Recent studies indicate that such exchange can be bidirectional when natural killer cells interact with their target cells. Sprent reviews the mechanisms involved in cell-cell molecular transfer and the receptor-ligand interactions involved.
Sprent
Jonathan
J
Department of Immunology, IMM4, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. jsprent@scripps.edu <jsprent@scripps.edu>
D000042:Absorption; D000818:Animals; D000938:Antigen-Presenting Cells / Q000737:chemistry*; D002462:Cell Membrane / Q000737:chemistry; D003599:Cytoskeleton / Q000502:physiology; D006680:HLA Antigens / Q000737:chemistry; D006649:Histocompatibility Antigens / Q000737:chemistry; D006801:Humans; D007518:Isoantibodies / Q000737:chemistry; D007694:Killer Cells, Natural / Q000737:chemistry*; D008024:Ligands; D051379:Mice; D008822:Mice, Transgenic; D011828:Radiation Chimera; D011948:Receptors, Antigen, T-Cell / Q000737:chemistry; D011971:Receptors, Immunologic / Q000737:chemistry*; D013499:Surface Properties; D013601:T-Lymphocytes / Q000737:chemistry* / Q000637:transplantation
D006680:HLA Antigens; D006649:Histocompatibility Antigens; D007518:Isoantibodies; D008024:Ligands; D011948:Receptors, Antigen, T-Cell; D011971:Receptors, Immunologic