title: Prolymphocytic leukaemia--report of three cases.
abstract: Prolymphocytic leukaemia is a rare subtype of chronic lymphocytic leukaemia. Three such cases are reported here along with clinical details. All these cases were seen in males above 5th decade of life. These patients showed moderate to massive splenomegaly, inconspicuous lymphadenopathy in two cases and one with minimal lymphadenopathy. Peripheral smear showed high leucocyte count with more than 55% of prolymphocytes. Bone marrow aspiration showed diffuse involvement; and in one with minimal lymphadenopathy, lymph node aspiration showed prolymphocytes. All the three patients died within a year after diagnosis.
authors.affiliation: Department of Pathology, Kasturba Medical College, Mangalore 575001.
authors.forename: Kapadi Surendra
authors.initials: KS
authors.lastname: Nayak
authors.lastname: Shankarnarayanan
authors.forename: Ramadas
authors.initials: R
authors.lastname: Naik
authors.forename: Urmila Niranjan
authors.initials: UN
authors.lastname: Khadilkar
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D015463:Leukemia, Prolymphocytic / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged
chemical_list: D000970:Antineoplastic Agents