Immunoprotective properties of transgenic plants expressing E2 glycoprotein from CSFV and cysteine protease from Fasciola hepatica.
Immune responses were elicited in laboratory animals after oral vaccination by transgenic plants (lettuce and alfalfa) expressing the E2 glycoprotein of Classical Swine Fever Virus (CSFV) or cysteine protease from Fasciola hepatica. ELISA analyses demonstrated that the oral route is effective in inducing a specific antibody response against these antigens in mice.
Legocki
Andrzej B
AB
Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704 Poznań, Poland. legocki@ibch.poznan.pl
Miedzinska
Katarzyna
K
Czaplińska
Magdalena
M
Płucieniczak
Andrzej
A
Wedrychowicz
Halina
H
D000818:Animals; D006692:Classical Swine Fever Virus / Q000276:immunology*; D003546:Cysteine Endopeptidases / Q000235:genetics / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005210:Fasciola hepatica / Q000235:genetics / Q000276:immunology*; D007114:Immunization; D007070:Immunoglobulin A / Q000096:biosynthesis; D007074:Immunoglobulin G / Q000096:biosynthesis; D007700:Kinetics; D018545:Lactuca; D000455:Medicago sativa; D051379:Mice; D030821:Plants, Genetically Modified / Q000276:immunology*; D014759:Viral Envelope Proteins / Q000096:biosynthesis* / Q000276:immunology*
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D014759:Viral Envelope Proteins; C087086:glycoprotein E2, classical swine fever virus; D003546:Cysteine Endopeptidases