title: Notable deuterium effect on the electron transfer rate of myoglobin.
abstract: The electron transfer reaction of wild-type myoglobin at an electrode was significantly facilitated in a D2O buffer as compared with that in an H2O buffer, with k(0)'(H2O)/k(0)'(D2O)= 0.13, while a minimal deuterium kinetic isotope effect on the myoglobin with modification at distal histidine (His-64) was observed.
authors.affiliation: National Institute of Advanced Industrial Science and Technology, 2-17-2-1, Tsukisamu-higashi, Sapporo, 062-8517, Japan. yasuhiro.mie@aist.go.jp
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Mie
authors.forename: Chiho
authors.initials: C
authors.lastname: Yamada
authors.forename: Tadayuki
authors.initials: T
authors.lastname: Uno
authors.forename: Saburo
authors.initials: S
authors.lastname: Neya
authors.forename: Fumio
authors.initials: F
authors.lastname: Mizutani
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Nishiyama
authors.forename: Isao
authors.initials: I
authors.lastname: Taniguchi
mesh_terms: D000818:Animals; D002021:Buffers; D017666:Deuterium Oxide / Q000737:chemistry*; D004566:Electrodes; D004579:Electron Transport; D007700:Kinetics; D009211:Myoglobin / Q000737:chemistry*; D013552:Swine
chemical_list: D002021:Buffers; D009211:Myoglobin; D017666:Deuterium Oxide