title: Saccharin as a salt former. Enhanced solubilities of saccharinates of active pharmaceutical ingredients.
abstract: Saccharin, acting as a weak acid, forms salts with basic APIs and these salts have the desirable property of enhanced water solubility.
authors.affiliation: School of Chemistry, University of Hyderabad, Hyderabad 500 046, India.
authors.forename: Prashant M
authors.initials: PM
authors.lastname: Bhatt
authors.forename: Nittala V
authors.initials: NV
authors.lastname: Ravindra
authors.forename: Rahul
authors.initials: R
authors.lastname: Banerjee
authors.forename: Gautam R
authors.initials: GR
authors.lastname: Desiraju
mesh_terms: D003460:Crystallization; D006860:Hydrogen Bonding; D008958:Models, Molecular; D015394:Molecular Structure; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D012439:Saccharin / Q000737:chemistry*; D012492:Salts; D012995:Solubility; D014867:Water / Q000737:chemistry
chemical_list: D004364:Pharmaceutical Preparations; D012492:Salts; D014867:Water; D012439:Saccharin