Occult hepatitis B virus infection in HIV-infected patients with isolated antibodies to hepatitis B core antigen: Aquitaine cohort, 2002-2003.
We prospectively assessed the prevalence of occult hepatitis B virus (HBV) infection by investigating HBV replication in 160 human immunodeficiency virus (HIV)-infected patients with isolated antibodies to hepatitis B core antigen. This prevalence was 0.6% (1 case/160 patients; 95% confidence interval, 0%-3.4%). A second serum sample was collected later from 52 of the patients. HBV DNA was once again undetectable in all patients, except for the sole patient who had previously been found to be HBV DNA positive.
Neau
Didier
D
Fédération de Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire (CHU), Hôpital Pellegrin, Bordeaux, France. didier.neau@chu-bordeaux.fr
Winnock
Maria
M
Jouvencel
Anne-Christine
AC
Faure
Murielle
M
Castéra
Laurent
L
Legrand
Elisabeth
E
Lacoste
Denis
D
Ragnaud
Jean-Marie
JM
Dupon
Michel
M
Fleury
Hervé
H
Lafon
Marie-Edith
ME
Dabis
François
F
D000328:Adult; D000368:Aged; D044966:Anti-Retroviral Agents / Q000627:therapeutic use; D000914:Antibodies, Viral / Q000097:blood*; D015331:Cohort Studies; D004279:DNA, Viral / Q000097:blood; D005260:Female; D005602:France / Q000453:epidemiology; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology; D006509:Hepatitis B / Q000097:blood* / Q000150:complications* / Q000453:epidemiology; D006512:Hepatitis B Core Antigens / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014779:Virus Replication
D044966:Anti-Retroviral Agents; D000914:Antibodies, Viral; D004279:DNA, Viral; D006512:Hepatitis B Core Antigens