title: Intra-hospital lethality among infants with pyogenic meningitis.
abstract: Predictor variables of intra-hospital lethality among infants with pyogenic meningitis due to Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae were identified using data from a follow-up study of infants with bacterial meningitis. The infants who were admitted to Couto Maia Hospital from March 1, 1997 to December 31, 1997 presenting with symptoms of bacterial meningitis were identified and included in a database. An analysis of the clinical and laboratory information was performed using EPI info 6.01b and SPSS 6.1 statistical programs. The total mortality rate was 17.1%, and the majority of deaths occurred within 48 hours of hospitalization. Factors associated most frequently with poor outcome included absence of respiratory infection, high cerebrospinal fluid protein, and compromised cranial nerves. Early identification of major risk groups is important to adopt measures to improve prognosis.
authors.affiliation: Division of Neurology and Epidemiology (DINEP)-Federal University of Bahia, Canela CEP:40.110-170 Salvador-Bahia, Brazil.
authors.forename: Rita
authors.initials: R
authors.lastname: Lucena
authors.forename: Natascha
authors.initials: N
authors.lastname: Fonseca
authors.forename: Luciana
authors.initials: L
authors.lastname: Nunes
authors.forename: Adriana
authors.initials: A
authors.lastname: Cardoso
authors.forename: Julieta
authors.initials: J
authors.lastname: Goes
authors.forename: Maria Cecília
authors.initials: MC
authors.lastname: Correia
authors.forename: Eduardo
authors.initials: E
authors.lastname: Cardoso
authors.forename: Fernanda
authors.initials: F
authors.lastname: Queirós
authors.forename: Luzia Poliana
authors.initials: LP
authors.lastname: Anjos
authors.forename: Camila
authors.initials: C
authors.lastname: Vila-Nova
authors.forename: Ailton
authors.initials: A
authors.lastname: Melo
mesh_terms: D002556:Cerebrospinal Fluid Proteins / Q000378:metabolism; D015331:Cohort Studies; D006192:Haemophilus Infections / Q000150:complications / Q000378:metabolism / Q000401:mortality*; D017052:Hospital Mortality; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007958:Leukocyte Count; D016920:Meningitis, Bacterial / Q000150:complications / Q000378:metabolism / Q000401:mortality*; D008589:Meningococcal Infections / Q000150:complications / Q000378:metabolism / Q000401:mortality*; D011008:Pneumococcal Infections / Q000150:complications / Q000378:metabolism / Q000401:mortality*; D012307:Risk Factors; D015996:Survival Rate
chemical_list: D002556:Cerebrospinal Fluid Proteins