[Studies on the chemical constituents in herb of Ranunculus sceleratus].
OBJECTIVE
To isolate and determine the chemical constituents from Ranunculus sceleratus.


METHODS
Six compounds were isolated and purified by extraction and different kinds of column chromatography. The structures were determined on the basis of extensive spectral analysis such as EI-MS, 1H-NMR, 13C-NMR, DEPT and NOEDS.


RESULTS
The structures were elucidated as stigmasta-4-ene-3,6-dione I, stigmasterol II, isoscopoletin III, scoparone IV, protocatechuic aldehyde V and protocatechuic acid VI, respectively.


CONCLUSIONS
Compound I, III, IV, V and VI were isolated from R. genus for the first time.
Gao
Xiao-zhong
XZ
Department of Traditional Chinese Medicine and Natural Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031, China.
Zhou
Chang-xin
CX
Zhang
Shui-li
SL
Yao
Wei
W
Zhao
Yu
Y
D001547:Benzaldehydes / Q000737:chemistry / Q000302:isolation & purification*; D002396:Catechols / Q000737:chemistry / Q000302:isolation & purification*; D002783:Cholestenones / Q000737:chemistry / Q000302:isolation & purification*; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification; D062385:Hydroxybenzoates / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D031947:Ranunculus / Q000737:chemistry*
D001547:Benzaldehydes; D002396:Catechols; D002783:Cholestenones; D003374:Coumarins; D062385:Hydroxybenzoates; C502125:stigmasta-4-ene-3,6-dione; C009091:protocatechuic acid; C005581:protocatechualdehyde; C018145:scoparone