title: Potential for enlarging DNA memory: the validity of experimental operations of scaled-up nested primer molecular memory.
abstract: DNA is an attractive memory unit because of its immense information density. Here, we describe a memory model made of DNA, called Nested Primer Molecular Memory (NPMM). NPMM consists of many DNA strands, and each DNA strand consists of two areas: a data area and a data address area. When the address of target data is specified, only the target data can be extracted from NPMM. In this paper, we evaluate the validity of the basic operations of NPMM and then discuss the feasibility of scaled-up NPMM through some laboratory experiments. In the latter, we deal with scaled-up NPMM simulated by the Concentration Scaling method.
authors.affiliation: Graduate School of Engineering, Hokkaido University, North 13, West 8, Kita-ku, Sapporo 060-8628, Japan. kashiwa@dna-comp.org
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kashiwamura
authors.forename: Masahito
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kameda
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Shiba
authors.forename: Azuma
authors.initials: A
authors.lastname: Ohuchi
mesh_terms: D000465:Algorithms; D019295:Computational Biology / Q000379:methods; D003198:Computer Simulation; D016248:Computer Storage Devices; D039301:Computers, Molecular; D003205:Computing Methodologies; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D016247:Information Storage and Retrieval / Q000379:methods*; D008954:Models, Biological; D008956:Models, Chemical; D009716:Numerical Analysis, Computer-Assisted
chemical_list: D004247:DNA