Reversible posterior leukoencephalopathy, cerebral vasoconstriction, and strokes after intravenous immune globulin therapy in guillain-barre syndrome.
The authors report a patient with Guillain-Barré syndrome who developed acute hypertension, reversible posterior leukoencephalopathy syndrome, ischemic and hemorrhagic strokes, and reversible cerebral arterial vasoconstriction shortly after initiating intravenous immune globulin therapy. Possible interrelationships and mechanisms of these complications are discussed.
Doss-Esper
Christine E
CE
Department of Neurology, Division of Critical Care and Emergency Neurology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02114, USA.
Singhal
Aneesh B
AB
Smith
Marsha S A
MS
Henderson
Galen V
GV
D000368:Aged; D001927:Brain Diseases / Q000209:etiology*; D002545:Brain Ischemia / Q000209:etiology; D002543:Cerebral Hemorrhage / Q000209:etiology; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D020275:Guillain-Barre Syndrome / Q000628:therapy*; D006801:Humans; D006973:Hypertension / Q000209:etiology; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging; D020521:Stroke / Q000209:etiology*; D020301:Vasospasm, Intracranial / Q000209:etiology*
D016756:Immunoglobulins, Intravenous