A case of pulmonary cryptococcosis with non-small cell lung cancer in idiopathic CD4+ T-lymphocytopenia.
Cryptococcus neoformans commonly causes opportunistic infections in immunocompromised patients, especially in patients with AIDS. CD4+ T-lymphocytopenia in AIDS indicates an increased risk of opportunistic infection and a decline in immunological function. Idiopathic CD4 T-lymphocytopenia (ICL) is characterized by depletions in the CD4+ T-cell subsets, without evidence of HIV infection. Immunodeficiency can exist in the absence of laboratory evidence of HIV infection, and T-cell subsets should be evaluated in patients who present with unusual opportunistic infections. We report a case of pulmonary cryptococcosis and lung cancer in a patient with persistently low CD4+ cell counts, without evidence of HIV infection.
Ahn
In-Seon
IS
Department of Internal Medicine, Inha University College of Medicine, 7-206 3-ga, Shinheung-dong, Joong-gu, Incheon, Korea.
Kim
Hee-gu
HG
Ryu
Jeong-Seon
JS
Kim
Lucia
L
Kwak
Seung-Min
SM
Lee
Hong-Lyeol
HL
Yoon
Yong-Hwan
YH
Cho
Jae-Hwa
JH
D000368:Aged; D018791:CD4 Lymphocyte Count; D015496:CD4-Positive T-Lymphocytes / Q000473:pathology*; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications* / Q000276:immunology; D003453:Cryptococcosis / Q000150:complications* / Q000276:immunology; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000276:immunology; D008231:Lymphopenia / Q000150:complications* / Q000276:immunology; D008297:Male
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