Association of right ventricular dysfunction with in-hospital mortality in patients with acute pulmonary embolism and reduction in mortality in patients with right ventricular dysfunction by pulmonary embolectomy.
Twenty-one of 64 patients (33%) with pulmonary embolisms with right ventricular (RV) dilation and 6 of 126 patients (5%) with pulmonary embolisms without RV dilation died during hospitalization (p <0.001). In the 64 patients with RV dilation, in-hospital mortality occurred in 2 of 18 hemodynamically unstable patients (11%) who underwent pulmonary embolectomy, in 2 of 6 hemodynamically stable patients (33%) treated with thrombolytic therapy plus intravenous heparin, and in 17 of 40 hemodynamically stable patients (43%) treated with intravenous heparin (p <0.025 comparing pulmonary embolectomy with no pulmonary embolectomy).
Sukhija
Rishi
R
Department of Medicine, Cardiology Division, Westchester Medical Center/New York Medical College, Valhalla, New York, USA.
Aronow
Wilbert S
WS
Lee
Jooyun
J
Kakar
Priyanka
P
McClung
John A
JA
Levy
James A
JA
Belkin
Robert N
RN
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D004452:Echocardiography; D017128:Embolectomy; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006493:Heparin / Q000627:therapeutic use; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000150:complications / Q000188:drug therapy / Q000401:mortality* / Q000601:surgery; D012189:Retrospective Studies; D015912:Thrombolytic Therapy; D018497:Ventricular Dysfunction, Right / Q000209:etiology / Q000401:mortality*
D005343:Fibrinolytic Agents; D006493:Heparin