Asymmetric alkylation of dimethoxyphosphoryl-N-[1-(S)-alpha-methylbenzyl]acetamide enolates. Synthesis of both stereoisomers from the same source of chirality by changing the equivalents of LDA.
A new methodology has been developed for the synthesis of both stereoisomers from a single chiral source.
Ordóñez
Mario
M
Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, 62210 Cuernavaca, Mor., Mexico. palacios@buzon.uaem.mx
Hernández-Fernández
Eugenio
E
Xahuentitla
Janet
J
Cativiela
Carlos
C