title: Acute aortic dissection presenting with primarily abdominal pain: a rare manifestation of a deadly disease.
abstract: The objective of this study was to determine the morbidity and mortality of patients with acute thoracic aortic dissections who present primarily with abdominal pain. Nine hundred ninety-two patients (mean age, 62.1 years +/- 14.1; 68% male) encountered from 1996 to 2001 with acute thoracic aortic dissections from the International Registry of acute Aortic Dissection were studied. Patient demographics, presenting symptoms, signs of aortic dissection, aortic pathology, and mortality were compared in patients presenting primarily with abdominal pain (group I, 46 patients, 4.6%) versus all others (group II). Demographics were similar between the two groups. When signs of aortic dissection were examined, 63% of patients in group I presented with hypertension compared to only 47% of patients in group II (p = 0.04). Patients in group I were less likely to present with evidence of end-organ malperfusion. Importantly, mortality in patients with a type B dissection, specifically following surgery for the dissection, was significantly increased in patients who presented primarily with abdominal pain (group I, 28% mortality vs. group II, 10.2% mortality; p = 0.02). This study documented increased mortality in patients with acute thoracic aortic dissections who present primarily with abdominal pain, underscoring the importance of maintaining a high index of suspicion for an aortic dissection in patients who have appropriate risk factors.
authors.affiliation: University of Michigan Health System, Ann Arbor, MI 48109-0329, USA. riversu@umich.edu
authors.forename: Gilbert R
authors.initials: GR
authors.lastname: Upchurch
authors.forename: Christoph
authors.initials: C
authors.lastname: Nienaber
authors.forename: Rossella
authors.initials: R
authors.lastname: Fattori
authors.forename: Arturo
authors.initials: A
authors.lastname: Evangelista
authors.forename: Jae
authors.initials: J
authors.lastname: Oh
authors.forename: Jeanna V
authors.initials: JV
authors.lastname: Cooper
authors.forename: Eric
authors.initials: E
authors.lastname: Isselbacher
authors.forename: Toru
authors.initials: T
authors.lastname: Suzuki
authors.forename: Kim A
authors.initials: KA
authors.lastname: Eagle
mesh_terms: D015746:Abdominal Pain / Q000209:etiology*; D000208:Acute Disease; D000368:Aged; D000784:Aortic Dissection / Q000150:complications* / Q000401:mortality / Q000601:surgery; D017545:Aortic Aneurysm, Thoracic / Q000150:complications* / Q000401:mortality / Q000601:surgery; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D016019:Survival Analysis