[A clinical study of pelvic floor electrical stimulation in treatment of overactive bladder].
OBJECTIVE
To observe the efficacy of electrical stimulation in treatment of overactive bladder (OAB).


METHODS
Patients (n = 60) with overactive bladder were randomly divided into 2 groups. Electrical stimulation group (n = 35) used an instrument for electrical stimulation through a special vagina or rectum probe transfer current (8-70 mA), for 20 min, qd, for 20-30 times. Medical group (n = 25) received oral tolterodine 2 mg, bid, for 2-4 weeks.


RESULTS
The total effective rate and cure rate were 74%, 37% in electrical stimulation group and 76%, 40% in medical group, respectively, showing no significant difference between two groups (P > 0.05). While patients' satisfactory rate was significantly higher in electrical stimulation group than in medical group (P < 0.05). Side effects were more commonly seen with tolterodine.


CONCLUSIONS
Electrical nerve stimulation is effective and safe for overactive bladder. Further studies are needed to show the long term efficacy and cost-effectiveness.
Lin
Li-sha
LS
Department of Obstetrics and Gynecology, Fuzhou General Hospital, Nanjing Military Command, Fuzhou 350025, China.
Song
Yan-feng
YF
Song
Jian
J
Chen
Mei-fang
MF
D000328:Adult; D000368:Aged; D001559:Benzhydryl Compounds / Q000009:adverse effects / Q000627:therapeutic use; D003248:Constipation / Q000209:etiology; D003408:Cresols / Q000009:adverse effects / Q000627:therapeutic use; D004599:Electric Stimulation Therapy / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006801:Humans; D008875:Middle Aged; D017773:Pelvic Floor / Q000503:physiopathology; D010665:Phenylpropanolamine / Q000009:adverse effects / Q000627:therapeutic use; D000068737:Tolterodine Tartrate; D016896:Treatment Outcome; D014549:Urinary Incontinence / Q000188:drug therapy / Q000628:therapy*; D014554:Urination / Q000187:drug effects; D014555:Urination Disorders / Q000188:drug therapy / Q000628:therapy*; D014987:Xerostomia / Q000209:etiology
D001559:Benzhydryl Compounds; D003408:Cresols; D010665:Phenylpropanolamine; D000068737:Tolterodine Tartrate