title: Inducible metronidazole resistance and nim genes in clinical Bacteroides fragilis group isolates.
abstract: Nitroimidazole resistance (nim) genes were detected in 2% of 1,502 clinical Bacteroides fragilis group strains isolated from 19 European countries, and a novel nim gene was identified. High metronidazole resistance could be induced in nim-positive strains, which emphasizes the importance of acknowledging metronidazole resistance in the clinical setting.
authors.affiliation: Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.
authors.forename: Sonja
authors.initials: S
authors.lastname: Löfmark
authors.forename: Hong
authors.initials: H
authors.lastname: Fang
authors.forename: Maria
authors.initials: M
authors.lastname: Hedberg
authors.forename: Charlotta
authors.initials: C
authors.lastname: Edlund
mesh_terms: D001441:Bacteroides fragilis / Q000187:drug effects* / Q000235:genetics; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D005798:Genes, Bacterial; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests
chemical_list: D008795:Metronidazole
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