[Detection for single nucleotide polymorphisms].
As the third generation of genetic markers SNPs (single nucleotide polymorphisms) has been used extensively in gene mapping,disease-correlativity analysis ,population genetics and drug research. Here methods for detection are reviewed. Most SNP genotyping are a combination of method for interrogating SNPs and analysis technique.It described both parts and give a outlook for detection.
Gao
Xiu-Li
XL
Shanghai Institute of Microsystem and Information Technology Chinese Academy of Science, Shanghai 200050, China. gxl_now@mail.sim.ac.cn
Jing
Feng-Xiang
FX
Yang
Jian-Bo
JB
Zhao
Jian-Long
JL
D005454:Fluorescence Polarization; D005819:Genetic Markers; D009693:Nucleic Acid Hybridization / Q000379:methods*; D020411:Oligonucleotide Array Sequence Analysis; D016133:Polymerase Chain Reaction / Q000379:methods*; D012150:Polymorphism, Restriction Fragment Length; D020641:Polymorphism, Single Nucleotide
D005819:Genetic Markers