Cellular organization by self-organization: mechanisms and models for Min protein dynamics.
We use the oscillating Min proteins of Escherichia coli as a prototype system to illustrate the current state and potential of modeling protein dynamics in space and time. We demonstrate how a theoretical approach has led to striking new insights into the mechanisms of self-organization in bacterial cells and indicate how these ideas may be applicable to more complex structure formation in eukaryotic cells.
Howard
Martin
M
Department of Mathematics, Imperial College London, London SW7 2AZ, England, UK. karsten@mpipks-dresden.mpg.de
Kruse
Karsten
K
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D001683:Biological Clocks / Q000502:physiology*; D018797:Cell Cycle Proteins; D002455:Cell Division / Q000502:physiology*; D003599:Cytoskeleton / Q000502:physiology*; D004926:Escherichia coli / Q000166:cytology / Q000502:physiology; D029968:Escherichia coli Proteins / Q000378:metabolism*; D008954:Models, Biological; D011485:Protein Binding
D018797:Cell Cycle Proteins; D029968:Escherichia coli Proteins; C093548:MinE protein, E coli; D000251:Adenosine Triphosphatases; C072069:MinD protein, E coli
Mol Microbiol. 1999 Oct;34(1):82-90
10540287
Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):4971-6
10220403
Mol Cell. 1999 Nov;4(5):673-82
10619015
Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3183-8
10737791
Phys Rev Lett. 2000 Aug 21;85(8):1778-81
10970612
Phys Rev Lett. 2000 May 29;84(22):5232-5
10990910
EMBO J. 2001 Apr 2;20(7):1563-72
11285221
Nature. 2001 Sep 6;413(6851):39-44
11544518
J Cell Biol. 2001 Oct 15;155(2):181-5
11604416
Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14202-7
11734639
Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):15078-83
11752455
Phys Rev Lett. 2001 Dec 31;87(27 Pt 1):278102
11800919
Biophys J. 2002 Feb;82(2):618-27
11806906
Proc Natl Acad Sci U S A. 2002 May 14;99(10):6761-6
11983867
J Cell Biol. 2002 Sep 16;158(6):1005-15
12235120
Curr Opin Microbiol. 2002 Dec;5(6):548-52
12457696
Science. 2002 Dec 6;298(5600):1942-6
12471245
Nat Cell Biol. 2003 Mar;5(3):175-8
12646867
Phys Rev Lett. 2003 Mar 28;90(12):128102
12688905
Phys Rev Lett. 2003 Apr 4;90(13):138102
12689327
J Mol Biol. 2003 May 23;329(1):35-43
12742016
Phys Rev E Stat Nonlin Soft Matter Phys. 2003 May;67(5 Pt 1):051913
12786184
Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7865-70
12766229
Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12724-8
14569005
J Mol Biol. 2004 Jan 9;335(2):655-63
14672671
Cell. 2003 Dec 12;115(6):705-13
14675535
Mol Cell. 2003 Dec;12(6):1477-87
14690601
Curr Biol. 2004 Jan 6;14(1):1-10
14711408
Nature. 2004 Jan 29;427(6973):415-8
14749823
Phys Rev Lett. 2004 Feb 20;92(7):078101
14995891
Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8643-8
15159537
J Bacteriol. 2004 Sep;186(17):5775-81
15317782
Cell. 2004 Sep 3;118(5):579-90
15339663
Proc Natl Acad Sci U S A. 1975 Aug;72(8):3102-6
1059095
Nature. 1998 Jan 8;391(6663):203-6
9428770
Mol Cell. 1999 Nov;4(5):665-72
10619014