title: CSF otorrhea complicating temporal bone osteoradionecrosis in a patient with nasopharyngeal carcinoma.
abstract: A 44-year-old Chinese man with a history of nasopharyngeal carcinoma that was treated with radiotherapy presented with fluid in the middle ear. We performed a myringotomy and subsequently made a diagnosis of cerebrospinal fluid (CSF) leakage secondary to osteoradionecrosis of the temporal bone. To the best of our knowledge, this is only the second reported case of an otogenic CSF leak resulting from osteoradionecrosis of the temporal bone. This case highlights the controversial role of myringotomy in the management of CSF otorrhea.
authors.affiliation: Department of Otolaryngology, Singapore General Hospital, Republic of Singapore.
authors.forename: Bernard Y K
authors.initials: BY
authors.lastname: Lim
authors.forename: Kenny Peter
authors.initials: KP
authors.lastname: Pang
authors.forename: Wong Kein
authors.initials: WK
authors.lastname: Low
authors.forename: How Ming
authors.initials: HM
authors.lastname: Tan
mesh_terms: D000328:Adult; D002277:Carcinoma / Q000532:radiotherapy*; D002558:Cerebrospinal Fluid Otorrhea / Q000209:etiology*; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy*; D010025:Osteoradionecrosis / Q000150:complications*; D011878:Radiotherapy / Q000009:adverse effects; D013701:Temporal Bone / Q000528:radiation effects*