Multiple superficial basal cell carcinomata--topical imiquimod versus curette and cryotherapy.
BACKGROUND
Superficial basal cell carcinoma can be successfully managed by means other than surgical excision. Nonexcisional approaches include topical imiquimod, and curette and cryotherapy (C&C).


OBJECTIVE
This article discusses the management of an insulin dependent diabetic man aged 52 years presenting with 17 torso basal cell carcinomas (BCCs); mostly superficial BCCs (SBCCs).


CONCLUSIONS
Half were treated with topical imiquimod. The remaining lesions were treated with curette and cryotherapy. All lesions resolved with proven histologic clearance. The patient considered C&C caused him less discomfort and disruption. He developed a late secondary infection in some sites treated with imiquimod. At 12 months there was no evidence of recurrence though new nodular BCCs and SBCCs had developed elsewhere on his upper torso. He has elected to have future SBCCs managed with C&C. While excisional surgery remains the benchmark management for nonmelanoma skin cancer, topical imiquimod and C&C are important options for treating SBCCs.
Dixon
Anthony J
AJ
Skincanceronly, Geelong, Victoria. anthony@skincanceronly.com
D000287:Administration, Topical; D000634:Aminoquinolines / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002280:Basal Cell Carcinoma / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D017679:Cryotherapy; D003475:Curettage; D006801:Humans; D000077271:Imiquimod; D008297:Male; D008875:Middle Aged; D055502:Secondary Prevention; D012878:Skin Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D016896:Treatment Outcome
D000634:Aminoquinolines; D000077271:Imiquimod