Coronary vasospasm leading to an acute myocardial infarction after the administration of dolasetron.
The 5-hydroxytryptamine antagonists are commonly used agents for the treatment of postoperative nausea and vomiting. However, these drugs can have significant cardiovascular adverse effects. We report a case of acute myocardial infarction after administration of dolasetron in a 17-year-old adolescent girl during strabismus corrective surgery.
Arole
Adebola
A
Department of Anesthesiology, Henry Ford Hospital, Detroit, MI 48202-2689, USA. aarole1@hfhs.org
Kroll
Henry R
HR
Brown
Morris
M
D000208:Acute Disease; D000293:Adolescent; D000932:Antiemetics / Q000009:adverse effects*; D003329:Coronary Vasospasm / Q000139:chemically induced* / Q000150:complications* / Q000628:therapy; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007211:Indoles / Q000009:adverse effects*; D016343:Monitoring, Intraoperative; D009203:Myocardial Infarction / Q000209:etiology* / Q000628:therapy; D013508:Ophthalmologic Surgical Procedures; D011807:Quinolizines / Q000009:adverse effects*; D012702:Serotonin Antagonists / Q000009:adverse effects*; D013285:Strabismus / Q000601:surgery
D000932:Antiemetics; D007211:Indoles; D011807:Quinolizines; D012702:Serotonin Antagonists; C060344:dolasetron