[Lymphocyte subpopulation changes in children with chronic virus hepatitis D and B].
We observed 367 children with chronic viral hepatitis Delta (CVHD) and B (CVHB) and found strict secondary T-immunodeficiency, more expressed in children with CVHD. We have found also the most characterizing changes of lymphocytes subpopulation and natural killer-cells depending on etiology of CVH. As for CVHD it is characterized by more significant decrease in CD4-lymphocytes, as for CVHB--CD8-lymphocytes. The above mentioned changes of lymphocytes subpopulation in patients with CVHD and CVHB show different pathological mechanisms of these two diseases, that should be taken into account treating such patients.
Abdumadzhidova
Sh U
ShU
Inoiatova
F I
FI
D000293:Adolescent; D016175:B-Lymphocyte Subsets / Q000166:cytology / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D019694:Hepatitis B, Chronic / Q000097:blood / Q000276:immunology*; D019701:Hepatitis D, Chronic / Q000097:blood / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D018655:Lymphocyte Count; D016176:T-Lymphocyte Subsets / Q000166:cytology / Q000276:immunology*