title: New concepts in the diagnosis and management of neurocysticercosis (Taenia solium).
abstract: Human neurocysticercosis, the infection of the nervous system by the larvae of Taenia solium, is a major cause of epileptic seizures and other neurologic morbidity worldwide. The diagnosis and treatment of neurocysticercosis have been considerably improved in recent years. This improvement includes identification and sequencing of specific antigens and development of new assays for laboratory diagnosis, recognition of the frequency and significance of edema around old, calcified cysts (associated to symptomatic episodes), results of a randomized blinded control treatment trial on treatment efficacy for intraparenchymal disease showing a clinical benefit of decreased seizures, and a much better assessment of the frequency and spectrum of cerebrovascular complications. These advances now permit a much better integration of clinical, serologic, and imaging data for diagnosis and therapeutic purposes.
authors.affiliation: Department of Microbiology, Universidad Peruana Cayetano Heredia, Lima, Peru. hgarcia@jhsph.edu
authors.forename: Hector H
authors.initials: HH
authors.lastname: Garcia
authors.forename: Oscar H
authors.initials: OH
authors.lastname: Del Brutto
authors.forename: Theodore E
authors.initials: TE
authors.lastname: Nash
authors.forename: A Clinton
authors.initials: AC
authors.lastname: White
authors.forename: Victor C W
authors.initials: VC
authors.lastname: Tsang
authors.forename: Robert H
authors.initials: RH
authors.lastname: Gilman
mesh_terms: D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D006801:Humans; D020019:Neurocysticercosis / Q000175:diagnosis* / Q000382:microbiology / Q000517:prevention & control*; D041201:Taenia solium
chemical_list: D000981:Antiprotozoal Agents