title: Neuromuscular disorders and sleep.
abstract: Neuromuscular disorders are caused by the primary involvement of the motor unit. In these patients, sleep-disordered breathing (SDB) due to respiratory muscle weakness is often encountered during sleep. Because there is a tendency to overlook this disorder, all patients with neuromuscular disorders should be questioned about SDB. Overnight polysomnography is the best investigation for SDB and nocturnal desaturations. In the management of these patients, noninvasive intermittent positive pressure ventilation results in improvement of SDB and breathing.
authors.affiliation: Stanford University Sleep Disorders Clinic, 401 Quarry Road, - Suite 3301, Palo Alto, CA 94305, USA. Ibrahim.Oztura@deu.edu.tr
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Oztura
authors.forename: Christian
authors.initials: C
authors.lastname: Guilleminault
mesh_terms: D006801:Humans; D009468:Neuromuscular Diseases / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D012890:Sleep / Q000502:physiology; D012893:Sleep Wake Disorders / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy
references.citation: Sleep Med. 2000 Feb 1;1(1):3-9
references.pmid: 10733615
references.citation: Neurology. 2003 Dec 23;61(12):1652-61
references.pmid: 14694025
references.citation: Neurology. 2001 Dec 11;57(11):2040-4
references.pmid: 11739823
references.citation: Lancet. 2003 Sep 20;362(9388):971-82
references.pmid: 14511932
references.citation: Muscle Nerve. 2000 Jul;23(7):1129-32
references.pmid: 10883011
references.citation: Muscle Nerve. 2000 Dec;23(12):1789-99
references.pmid: 11102902
references.citation: Curr Opin Neurol. 2001 Oct;14(5):629-34
references.pmid: 11562575
references.citation: Neurology. 2004 Feb 10;62(3):513-4
references.pmid: 14872048
references.citation: Neurology. 2001 Oct 9;57(7):1290-5
references.pmid: 11591850
references.citation: Am J Phys Med Rehabil. 2003 Nov;82(11):866-70
references.pmid: 14566155
references.citation: Sleep Med. 2000 Apr 1;1(2):139-144
references.pmid: 10767656
references.citation: Am J Respir Crit Care Med. 2003 Jul 1;168(1):10-48
references.pmid: 12826594
references.citation: Sleep. 2002 Sep 15;25(6):662-5
references.pmid: 12224846
references.citation: J Pediatr (Rio J). 2002 Jul;78 Suppl 1:S89-S103
references.pmid: 14676872
references.citation: Swiss Med Wkly. 2002 Mar 9;132(9-10):109-15
references.pmid: 12045998
references.citation: Muscle Nerve. 2004 Jan;29(1):5-27
references.pmid: 14694494
references.citation: Am J Respir Crit Care Med. 2000 Jan;161(1):166-70
references.pmid: 10619815
references.citation: Am J Respir Crit Care Med. 2002 Jan 15;165(2):250-3
references.pmid: 11790663
references.citation: Pediatr Neurol. 2000 Aug;23(2):107-13
references.pmid: 11020635
references.citation: Pediatr Pulmonol. 2000 Feb;29(2):135-40
references.pmid: 10639204
references.citation: Ann N Y Acad Sci. 2003 Sep;998:138-60
references.pmid: 14592871
references.citation: Eur Respir J. 2003 Oct;22(4):654-60
references.pmid: 14582920
references.citation: Am J Respir Crit Care Med. 2001 Feb;163(2):540-77
references.pmid: 11179136
references.citation: J Neurol Sci. 1999 Oct 31;169(1-2):61-8
references.pmid: 10540009
references.citation: Muscle Nerve. 1999 Nov;22(11):1498-509
references.pmid: 10514227
references.citation: JAMA. 2000 Jul 26;284(4):412-4
references.pmid: 10904484
references.citation: Am J Respir Crit Care Med. 1999 Jul;160(1):198-202
references.pmid: 10390400
references.citation: J Neurol Sci. 1999 Mar 15;164(1):37-43
references.pmid: 10385045
references.citation: Neurology. 1999 Jun 10;52(9):1777-83
references.pmid: 10371523
references.citation: Am J Respir Crit Care Med. 2001 Oct 1;164(7):1182-5
references.pmid: 11673206
references.citation: Pediatr Pulmonol. 2000 Feb;29(2):141-50
references.pmid: 10639205
references.citation: Chest. 1999 Jun;115(6):1553-62
references.pmid: 10378548
references.citation: Lancet. 2001 Jan 27;357(9252):267-72
references.pmid: 11214130
references.citation: Lancet. 2001 Jun 30;357(9274):2122-8
references.pmid: 11445126
references.citation: J Neurol. 1999 Apr;246(4):275-82
references.pmid: 10367695
references.citation: Muscle Nerve. 2001 Apr;24(4):451-5
references.pmid: 11268015
references.citation: Eur Respir J. 2002 Jun;19(6):1194-201
references.pmid: 12108875
references.citation: Chest. 2004 Jan;125(1):334-6
references.pmid: 14718463
references.citation: Muscle Nerve. 2000 Oct;23(10):1488-502
references.pmid: 11003783
references.citation: Neurology. 2002 Dec 24;59(12):1876-80
references.pmid: 12499477
references.citation: Sleep. 2003 May 1;26(3):287-90
references.pmid: 12749547
references.citation: Am J Respir Crit Care Med. 2000 Mar;161(3 Pt 1):849-56
references.pmid: 10712332
references.citation: Muscle Nerve. 2000 Oct;23(10):1456-71
references.pmid: 11003781
references.citation: Curr Opin Neurol. 2003 Oct;16(5):559-68
references.pmid: 14501839
references.citation: J Neurol Sci. 1999 Nov 30;170(2):77-89
references.pmid: 10561522