Albumin-conjugated corrole metal complexes: extremely simple yet very efficient biomimetic oxidation systems.
An extremely simple biomimetic oxidation system, consisting of mixing metal complexes of amphiphilic corroles with serum albumins, utilizes hydrogen peroxide for asymmetric sulfoxidation in up to 74% ee. The albumin-conjugated manganese corroles also display catalase-like activity, and mechanistic evidence points toward oxidant-coordinated manganese(III) as the prime reaction intermediate.
Mahammed
Atif
A
Department of Chemistry and Institute of Catalysis Science and Technology, Technion-Israel Institute of Technology, Haifa 32000, Israel.
Gross
Zeev
Z
D000818:Animals; D040761:Biomimetic Materials / Q000737:chemistry; D002374:Catalase / Q000737:chemistry; D006801:Humans; D006861:Hydrogen Peroxide / Q000737:chemistry; D058085:Iron Compounds / Q000737:chemistry; D008345:Manganese / Q000737:chemistry*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D011166:Porphyrins / Q000737:chemistry*; D012709:Serum Albumin / Q000737:chemistry*; D012756:Sheep; D013552:Swine
D058085:Iron Compounds; D011166:Porphyrins; D012709:Serum Albumin; C431863:corrole; D008345:Manganese; D006861:Hydrogen Peroxide; D002374:Catalase; D010100:Oxygen