title: Effect of MTAD on postoperative discomfort: a randomized clinical trial.
abstract: The purpose of this study was to compare levels of postoperative discomfort after cleaning and shaping of root canals using two protocols for removal of smear layer. Seventy-three consecutive patients requiring root canal treatment were included. At random, canals were cleaned and shaped with one of the following protocols. In group 1, 5.25% sodium hypochlorite was used as the root canal irrigant. The smear layer was removed by placing 17% EDTA in the canal(s) for 1 min followed by a 5-ml rinse with 5.25% NaOCl. In group 2, canals were irrigated with 1.3% NaOCl; the smear layer was removed by placing MTAD in the canal(s) for 5 min. Access cavities were closed with a sterile cotton pellet and Cavit. The patients recorded degree of discomfort at various time intervals after cleaning and shaping on a visual analogue scale for 1 wk. No significant statistical difference was found in the degree of discomfort between the two groups (p = 0.58).
authors.affiliation: Department of Endodontics, School of Dentistry, Loma Linda University, Loma Linda, CA 92350, USA. mtorabinejad@sd.llu.edu
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Torabinejad
authors.forename: Shahrokh
authors.initials: S
authors.lastname: Shabahang
authors.forename: Khaled
authors.initials: K
authors.lastname: Bahjri
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D002614:Chelating Agents; D016009:Chi-Square Distribution; D004492:Edetic Acid; D006801:Humans; D010149:Postoperative Pain / Q000209:etiology*; D011136:Polysorbates / Q000009:adverse effects*; D012388:Root Canal Irrigants / Q000009:adverse effects; D018915:Root Canal Preparation / Q000009:adverse effects / Q000379:methods*; D016369:Smear Layer; D012973:Sodium Hypochlorite; D013501:Surface-Active Agents / Q000009:adverse effects*; D011795:Surveys and Questionnaires; D014098:Toothache / Q000209:etiology*
chemical_list: D002614:Chelating Agents; D011136:Polysorbates; D012388:Root Canal Irrigants; D013501:Surface-Active Agents; D004492:Edetic Acid; D012973:Sodium Hypochlorite