[Treatment of postmenopausal osteoporosis].
The treatment of postmenopausal osteoporosis relies on management of some risk factors for fracture, e.g., risk factors for falls, improvement of calcium and vitamin D intake, and on various medications. All elderly women with calcium and vitamin D deficiency should receive calcium and vitamin D supplements. Estrogen replacement therapy should not longer be used to prevent or treat postmenopausal osteoporosis, owing to its poor long-term risk/benefit ratio. Raloxifene, biphosphonates (alendronate, risedronate) are well tolerated compounds with proven anti-fracture efficacy. Teriparatide is a new bone forming agent to treat severe osteoporosis. Strontium ranelate is a new drug also reducing the risk of fractures that should be available soon.
Chapurlat
Roland
R
Service de rhumatologie et de pathologie osseuse, hôpital Edouard Herriot, 69437 Lyon Cedex 03. chapurlat@lyon.inserm.fr
Delmas
Pierre D
PD
D003663:Decision Trees; D005260:Female; D006801:Humans; D010024:Osteoporosis / Q000188:drug therapy*; D017698:Postmenopause