4-Hydroxy-1-(3-pyridyl)-1-butanone, an indicator for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA damage, is not detected in human pancreatic tissue.
Prokopczyk
Bogdan
B
Department of Pharmacology, H078, Penn State College of Medicine, 500 University Drive, Hershey, PA 17033-0805, USA. bprokopczyk@psu.edu
Leder
Gerhard
G
Trushin
Neil
N
Cunningham
A John
AJ
Akerkar
Shobha
S
Pittman
Brian
B
Ramadani
Marco
M
Straeter
Joern
J
Beger
Hans G
HG
Henne-Bruns
Doris
D
El-Bayoumy
Karam
K
D002074:Butanones / Q000378:metabolism*; D018736:DNA Adducts; D004249:DNA Damage; D006801:Humans; D009602:Nitrosamines / Q000378:metabolism*; D010179:Pancreas / Q000378:metabolism*; D010190:Pancreatic Neoplasms; D011725:Pyridines / Q000378:metabolism*; D012907:Smoking
D002074:Butanones; D018736:DNA Adducts; D009602:Nitrosamines; D011725:Pyridines; C016583:4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; C482281:4-hydroxy-1-(3-pyridyl)-1-butanone