Fluorometric sensing of the salt-induced B-Z DNA transition by combination of two pyrene-labeled nucleobases.
We have developed a new fluorescent DNA sensor containing two pyrene-labeled nucleobases, (Pet)G and (Py)C, and the fluorescence color was altered by the salt-induced B-Z DNA transition.
Okamoto
Akimitsu
A
Department of Synthetic Chemistry and Biological Chemistry, Faculty of Engineering, Kyoto University, Kyoto 615-8510, Japan. okamoto@sbchem.kyoto-u.ac.jp
Ochi
Yuji
Y
Saito
Isao
I
D001482:Base Composition; D043542:DNA, Z-Form / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D005470:Fluorometry / Q000379:methods*; D015394:Molecular Structure; D011721:Pyrenes / Q000737:chemistry*; D012965:Sodium Chloride / Q000737:chemistry*
D043542:DNA, Z-Form; D005456:Fluorescent Dyes; D011721:Pyrenes; D012965:Sodium Chloride; C030984:pyrene