Mycgranol, a new diterpene from the marine sponge Mycale aff. graveleyi.
Mycgranol, a new isocopalane diterpene (methyl 1beta-hydroxy-2-oxoisocopalanoate) was isolated from the Kenyan sponge Mycale (Aegogropila) aff. graveleyi. The structure of the compound was elucidated by interpretation of MS, COSY, HMQC, HMBC, and ROESY data. The absolute configuration of mycgranol was determined to be the same as that of the nudibranch isocopalane diterpenes rather than that of the ent-compounds known from sponges of the genus Spongia.
Rudi
Amira
A
School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel-Aviv University, Ramat Aviv 69978, Israel.
Benayahu
Yehuda
Y
Kashman
Yoel
Y
D000818:Animals; D004224:Diterpenes / Q000737:chemistry / Q000145:classification / Q000302:isolation & purification*; D007630:Kenya; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011161:Porifera / Q000737:chemistry*
D004224:Diterpenes; C499275:mycgranol