Agenesis of tibia with bifid femur, congenital heart disease, and cleft lip with cleft palate or tracheoesophageal fistula: possible variants of Gollop-Wolfgang complex.
Two patients with bifurcation of one femur, ipsilateral absence of tibia and one partially formed tibia, or bilateral absent tibiae, club feet with normal or nearly normal digits, congenital heart disease and, in one case, tracheoesophageal fistula; in the second, cleft lip and cleft palate and enlarged head with increased fluid and lissencephaly, are described. These appear to be unique combinations of defects but overlap with the Gollop-Wolfgang complex is present, particularly with the case of possible Gollop-Wolfgang described by Raas-Rothschild et al.
Erickson
Robert P
RP
Department of Pediatrics, Molecular and Cellular Biology, University of Arizona, Tucson, AZ 85724-5073, USA. erickson@peds.arizona.edu
D000015:Abnormalities, Multiple / Q000235:genetics / Q000473:pathology*; D002971:Cleft Lip / Q000473:pathology*; D002972:Cleft Palate / Q000473:pathology*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D005269:Femur / Q000002:abnormalities*; D005385:Fingers / Q000002:abnormalities; D006330:Heart Defects, Congenital / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D013577:Syndrome; D013977:Tibia / Q000002:abnormalities*; D014138:Tracheoesophageal Fistula / Q000473:pathology