title: Transtaganolides A-D: novel metabolites from Thapsia transtagana.
abstract: Four novel and unusual C-19 compounds from Thapsia transtagana, named transtaganolides A-D, have been isolated. Their structures were established by physical methods, including X-ray analysis of transtaganolides A and B. This is the first time that a 7-methoxy-4,5-dihydro-3H-oxepin-2-one ring has been found in a natural product. [structure: see text]
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, Apartado 40, 11510 Puerto Real, Cádiz, Spain.
authors.forename: Abderrahmane
authors.initials: A
authors.lastname: Saouf
authors.forename: Francisco M
authors.initials: FM
authors.lastname: Guerra
authors.forename: Juan J
authors.initials: JJ
authors.lastname: Rubal
authors.forename: F Javier
authors.initials: FJ
authors.lastname: Moreno-Dorado
authors.forename: Mohamed
authors.initials: M
authors.lastname: Akssira
authors.forename: Fouad
authors.initials: F
authors.lastname: Mellouki
authors.forename: Matías
authors.initials: M
authors.lastname: López
authors.forename: Antonio J
authors.initials: AJ
authors.lastname: Pujadas
authors.forename: Zacarías D
authors.initials: ZD
authors.lastname: Jorge
authors.forename: Guillermo M
authors.initials: GM
authors.lastname: Massanet
mesh_terms: D019661:Apiaceae / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004452:Echocardiography; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry* / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D006576:Heterocyclic Compounds, 4 or More Rings