title: Real-time verification of HDR brachytherapy source location: implementation of detector redundancy.
abstract: Independent treatment verification for high dose rate (HDR) brachytherapy is needed to ensure that the treatment proceeds as prescribed. In this paper, we investigate the feasibility of a proposed real-time source position verification process. This process provides immediate confirmation of the source position during the treatment, so that the treatment can be aborted and modified if necessary. We show that an array of dosimeters placed on the patient's skin can independently verify the position in three dimensions. This verification was demonstrated by using a diamond detector placed in several locations on the surface of an anthropomorphic phantom. A mathematical algorithm was constructed to estimate the location of the source given a measured data set in the presence of tissue heterogeneity. The accuracy of the source localization was found to increase with the number of detectors used to compute the estimation of the source position. The resolution to which the 12 detectors can identify the location of the source was within 3 mm.
authors.affiliation: Department of Physics, University of Sydney, Sydney, Australia. Tatsuya.nakano@email.cs.nsw.gov.au
authors.forename: T
authors.initials: T
authors.lastname: Nakano
authors.forename: N
authors.initials: N
authors.lastname: Suchowerska
authors.forename: D R
authors.initials: DR
authors.lastname: McKenzie
authors.forename: M M
authors.initials: MM
authors.lastname: Bilek
mesh_terms: D000465:Algorithms; D000818:Animals; D003198:Computer Simulation; D003199:Computer Systems; D006801:Humans; D008954:Models, Biological; D011874:Radiometry / Q000295:instrumentation / Q000379:methods*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation / Q000379:methods; D011881:Radiotherapy, Computer-Assisted / Q000295:instrumentation / Q000379:methods*; D012062:Relative Biological Effectiveness; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity