Stereoselective synthesis of cyercene A and the placidenes.
Members of a family of alpha-methoxy-gamma-pyrone-containing polypropionate natural products have been stereoselectively synthesized. Two key iodovinyl pyrone building blocks were coupled to appropriately selected vinyl stannanes to assemble the highly substituted polyene side chains of the natural products. [structure: see text]
Liang
Guangxin
G
Center for New Directions in Organic Synthesis, Department of Chemistry, University of California-Berkeley, Berkeley, CA 94720. USA.
Miller
Aubry K
AK
Trauner
Dirk
D
D001688:Biological Products / Q000138:chemical synthesis*; D002384:Catalysis; D007202:Indicators and Reagents; D015394:Molecular Structure; D011753:Pyrones / Q000138:chemical synthesis*; D013237:Stereoisomerism
D001688:Biological Products; D007202:Indicators and Reagents; D011753:Pyrones; C501019:cyercene A