title: Gastric schwannoma.
abstract: Gastrointestinal mesenchymal tumors are a group of tumors originated from the mesenchymal stem cells of the gastrointestinal tract, consisting of gastrointestinal stromal tumors (GIST), leiomyomas or leiomyosarcomas or schwannomas. Gastric schwannoma is a very rare gastrointestinal mesenchymal tumor, which represents only 0.2% of all gastric tumors and 4% of all benign gastric neoplasms. We report a 24-year-old girl who suffered from an episode of upper gastrointestinal bleeding. The endoscopic examination showed a round submucosal tumor with a central ulceration and bleeding over the high body of the stomach. Surgical resection of the tumor was performed. The pathological examination revealed a picture of spindle cell tumor that was strongly positive for S-100 protein stain, and non-reactive for CD34, CD117, actin, HHF-35, desmin, melan-A and HMB-45, consistent with gastric schwannoma. The literature is reviewed.
authors.affiliation: Taipei Veterans General Hospital, Taiwan.
authors.forename: Chen-Sung
authors.initials: CS
authors.lastname: Lin
authors.forename: Han-Shui
authors.initials: HS
authors.lastname: Hsu
authors.forename: Chien-Ho
authors.initials: CH
authors.lastname: Tsai
authors.forename: Wing-Yin
authors.initials: WY
authors.lastname: Li
authors.forename: Min-Hsiung
authors.initials: MH
authors.lastname: Huang
mesh_terms: D000328:Adult; D020776:Endoscopes, Gastrointestinal; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D009442:Neurilemmoma / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D009418:S100 Proteins / Q000032:analysis; D013270:Stomach / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology; D013274:Stomach Neoplasms / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D013276:Stomach Ulcer / Q000150:complications; D014057:Tomography, X-Ray Computed
chemical_list: D009418:S100 Proteins