[Tailed normal chromatographic peak expressed by plate model].
An equation for describing tailed normal chromatographic peak is derived based on the plate model. In terms of the de Moivre-Laplace theorem, which states that a binomial distribution can be approximated by the Gaussian distribution for large sample size, it is suggested that the concentration distribution along the distance downstream from the inlet of chromatographic column conforms to the Gaussian distribution function, but the concentration distribution with elution volume (or elution time) does not. The equation developed here, which is similar to the Gaussian distribution function, indicates that the normal chromatographic elution curve should be a tailing one. It is also shown that the symmetric Gaussian elution curve is an approximate solution of the plate model and can be obtained by the approximation of the equation here. The equation is proved to be congruent to the results of the diffusion model. Thus, the plate model and diffusion model are equivalent to each other in describing chromatographic process although different mechanism is based on.
Han
Z
Z
Chemical Engineering Research Center of Tianjin University, Tianjin, 300072.
He
Z
Z
Yu
G
G