The multiple faces of nonsteroidal antiinflammatory drug hypersensitivity.
Based on the clinical picture and triggering drugs, allergic and pseudoallergic adverse reactions to nonsteroidal anti-inflammatory drugs (NSAIDs) can be classified in four patterns : respiratory, cutaneous, mixed and systemic. This categorization is useful for the purpose of describing patient populations included in studies about NSAID adverse reactions as well as for the routine management of the patient in the clinical setting.
Sánchez-Borges
M
M
Centro Médico-Docente La Trinidad, Clínica El Avila, Caracas, Venezuela. malsan@cantv.net
Capriles-Hulett
A
A
Caballero-Fonseca
F
F
D000799:Angioedema / Q000139:chemically induced; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D001249:Asthma / Q000139:chemically induced; D004342:Drug Hypersensitivity / Q000209:etiology*; D006801:Humans; D012119:Respiration / Q000187:drug effects; D014581:Urticaria / Q000139:chemically induced
D000894:Anti-Inflammatory Agents, Non-Steroidal