Enantioselective synthesis of homoallylic alcohols via a chiral In(III)-PYBOX complex.
In the presence of 20 mol% of a chiral catalytic complex prepared from In(OTf)(3) and chiral PYBOX, allyltributylstannane reacted with aldehydes to afford the corresponding homoallylic alcohols in moderate to high enantioselectivities (60-93% ee).
Lu
Jun
J
Department of Chemistry, National University of Singapore, Singapore.
Hong
Mei-Ling
ML
Ji
Shun-Jun
SJ
Loh
Teck-Peng
TP
D000438:Alcohols / Q000138:chemical synthesis / Q000737:chemistry*; D000498:Allyl Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D046911:Macromolecular Substances; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010080:Oxazoles / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*; D013237:Stereoisomerism
D000438:Alcohols; D000498:Allyl Compounds; D046911:Macromolecular Substances; D009942:Organometallic Compounds; D010080:Oxazoles; D011725:Pyridines; C510741:indium(III)-PYBOX