title: Prolonged pH monitoring: Bravo capsule.
abstract: The Bravo pH monitoring system is a safe and well-tolerated reliable method for measuring esophageal acid exposure. Key potential advantages of this system are related to its ability to be unobtrusive, comfortable, and provide study periods of longer duration. These advantages make it an excellent option for subjects who are unwilling or unable to tolerate conventional catheter pH monitoring. Whether the Bravo capsule improves diagnostic accuracy is still unclear; however, initial results are promising and further validation studies are expected. Whether this method is preferred over conventional monitoring for diagnostic evaluation depends on multiple considerations ranging from cost to possible contraindications for both systems. Further refinements in methodology and recording protocol are likely to be made, which will improve diagnostic accuracy and lower cost.
authors.affiliation: Department of Medicine, Northwestern University, The Feinberg School of Medicine, 676 N. St. Clair Street, Suite 1400, Chicago, IL 60611, USA. j-pandolfino@northwestern.edu
authors.forename: John E
authors.initials: JE
authors.lastname: Pandolfino
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Kahrilas
mesh_terms: D002404:Catheterization / Q000379:methods; D004867:Equipment Design; D004869:Equipment Safety; D005745:Gastric Acidity Determination / Q000295:instrumentation*; D005764:Gastroesophageal Reflux / Q000175:diagnosis*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D008991:Monitoring, Physiologic / Q000295:instrumentation* / Q000379:methods; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D013997:Time Factors
chemical_list: D007202:Indicators and Reagents