title: The Aral Sea disaster--human biomonitoring of Hg, As, HCB, DDE, and PCBs in children living in Aralsk-and Akchi, Kazakhstan.
abstract: Mercury and arsenic have been measured in urine samples and HCB, DDE and PCBs in blood samples of children from Aralsk and Akchi, Kazakhstan. Due to the special situation of Aralsk in the desert left by the drying out Aral Sea, environmental pollution with heavy metals and organic contaminants is believed to be higher than elsewhere in Kazakhstan. Aralsk was formerly located at the shore of the Aral Sea and is now far away from it. Akchi is a similar village and was included in this study as a Kazakh reference site. Urine concentrations of arsenic were higher in Akchi (9.4 microg/l) than in Aralsk (5.5 microg/l) and compared to children from Mannheim, Germany (4.25 microg/l; Median values). Regarding Hg, differences between children of Aralsk and Akchi were not significant and concentrations were lower than reference values from Germany. DDE contamination of children from Aralsk (2.48 microg/l) was significantly higher compared to Akchi (1.35 microg/l). DDE concentrations in blood samples from children in both cities were also significantly higher than the German reference value (0.7 microg/l). HCB and PCBs levels differed significantly between both Kazakh groups. However, concentrations of these compounds were lower than German reference values and there was no significant difference to samples from Mannheim children.
authors.affiliation: University of Heidelberg, Institute for Hygiene, Dep. Hygiene and Med. Microbiology, Heidelberg, Germany. Lothar.Erdinger@urz.uni-hd.de
authors.forename: Lothar
authors.initials: L
authors.lastname: Erdinger
authors.forename: Peter
authors.initials: P
authors.lastname: Eckl
authors.forename: Faina
authors.initials: F
authors.lastname: Ingel
authors.forename: Shulpan
authors.initials: S
authors.lastname: Khussainova
authors.forename: Elmira
authors.initials: E
authors.lastname: Utegenova
authors.forename: Volker
authors.initials: V
authors.lastname: Mann
authors.forename: Thomas
authors.initials: T
authors.lastname: Gabrio
mesh_terms: D001151:Arsenic / Q000652:urine; D001822:Body Burden; D002648:Child; D002675:Child, Preschool; D003633:Dichlorodiphenyl Dichloroethylene / Q000097:blood*; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000097:blood* / Q000652:urine; D005659:Fungicides, Industrial / Q000097:blood; D006581:Hexachlorobenzene / Q000097:blood; D006801:Humans; D007306:Insecticides / Q000097:blood*; D007623:Kazakhstan; D008628:Mercury / Q000652:urine; D009792:Oceans and Seas; D011078:Polychlorinated Biphenyls / Q000097:blood
chemical_list: D004785:Environmental Pollutants; D005659:Fungicides, Industrial; D007306:Insecticides; D003633:Dichlorodiphenyl Dichloroethylene; D006581:Hexachlorobenzene; D011078:Polychlorinated Biphenyls; D008628:Mercury; D001151:Arsenic