title: Angiosarcoma of the breast: A case report and literature review.
abstract: OBJECTIVE
  Primary angiosarcoma of the breast is a rare occurrence.
  
  
  METHODS
  We report a case of a 35- year-old woman who presented with a highly vascular mass that had nearly replaced her right breast.
  
  
  RESULTS
  Initial diagnosis reported the tumor as benign. However, permanent sections were sent to the Mayo Clinic, where the diagnosis of angiosarcoma of the breast was confirmed. The mass was removed via a total mastectomy. Adjuvant chemotherapy was also prescribed. A review of the literature suggested that the benefits of adjuvant chemotherapy were not well defined, but in the case described, adjuvant chemotherapy appeared to offer the best prognosis.
  
  
  CONCLUSIONS
  Preoperative radiography is generally not indicated for angiosarcoma. Primary angiosarcoma of the breast is difficult to diagnose, with no pathognomonic features radiographically. We concluded that solid-appearing breast tumors, which are also highly vascular, should be considered malignant until proven otherwise. Surgical removal followed by adjuvant chemotherapy appears to afford the best prognosis.
authors.affiliation: Department of Surgery, Temple University/Conemaugh's Memorial Medical Center, Johnstown, Pennsylvania, USA.
authors.forename: Colleen M
authors.initials: CM
authors.lastname: Johnson
authors.forename: Gerard A
authors.initials: GA
authors.lastname: Garguilo