[Inflammatory bowel disease--diagnosis and therapy].
The first intention in the management of patients with inflammatory bowel disease (IBD) is the improvement of quality of life. It is important to avoid unnecessary investigations and to protect the patients from therapeutic approaches, which efficacy is not proven. The following remarks are based on the guidelines of The German Society of Gastroenterology for diagnosis and therapy of ulcerative colitis and Crohn's disease, which include an accurate diagnosis, the treatment of the acute phase, the maintaining of remission and the management of complications. The therapy depends on the severity of the acute phase and on the localisation of the disease. Immunosuppressive therapy with azathioprine or mercaptopurine is indicated in patients with steroid-dependent or steroid-resistant disease.
Vogt
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Medizinische Klinik, Fachbereich Gastroenterologie, Akademisches Lehrkrankenhaus der Universität Tübingen, Städtische Kliniken Esslingen.
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001241:Aspirin / Q000008:administration & dosage / Q000627:therapeutic use; D001379:Azathioprine / Q000008:administration & dosage / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy; D018849:Controlled Clinical Trials as Topic; D003424:Crohn Disease / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy; D015122:Mercaptopurine / Q000008:administration & dosage / Q000627:therapeutic use; D010919:Placebos; D017410:Practice Guidelines as Topic; D011788:Quality of Life; D012074:Remission Induction; D013997:Time Factors
D000305:Adrenal Cortex Hormones; D000894:Anti-Inflammatory Agents, Non-Steroidal; D007166:Immunosuppressive Agents; D010919:Placebos; D015122:Mercaptopurine; D001379:Azathioprine; D001241:Aspirin