Genetic analysis of bovine viral diarrhoea viruses from Australia.
Eighty-nine bovine viral diarrhoea viruses (BVDV) from Australia have been genetically typed by sequencing of the 5' untranslated region (5'-UTR) and for selected isolates the N(pro) region of the viral genome. Phylogenetic reconstructions indicated that all of the samples examined clustered within the BVDV type 1 genotype. Of the 11 previously described genetic groups of BVDV-1, 87 of the samples examined in this study clustered with the BVDV-1c, while two samples clustered with the BVDV-1a. Based on these analyses there appears to be limited genetic variation within the Australian BVDV field isolates. In addition, the phylogenetic reconstructions indicate that the clustering of Australian BVDV in the phylogenetic trees is not a result of geographic isolation.
Mahony
Timothy J
TJ
Department of Primary Industries and Fisheries, Level 6 North, Queensland Biosciences Precinct, 306 Carmody Road, Brisbane, Qld 4072, Australia. timothy.mahony@dpi.qld.gov.au
McCarthy
Fiona M
FM
Gravel
Jennifer L
JL
Corney
Bruce
B
Young
Peter L
PL
Vilcek
Stefan
S
D020121:5' Untranslated Regions / Q000737:chemistry / Q000235:genetics; D000818:Animals; D001315:Australia; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000821:virology*; D002417:Cattle; D001908:Diarrhea Viruses, Bovine Viral / Q000235:genetics*; D014644:Genetic Variation; D010802:Phylogeny; D012367:RNA, Viral / Q000737:chemistry / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000662:veterinary; D017422:Sequence Analysis, DNA
D020121:5' Untranslated Regions; D012367:RNA, Viral