title: Transforming growth factor-beta : biology and clinical relevance.
abstract: Transforming growth factor-beta is a pleiotropic growth factor that has enthralled many investigators for approximately two decades. In addition to many reports that have clarified the basic mechanism of transforming growth factor-beta signal transduction, numerous laboratories have published on the clinical implication/application of transforming growth factor-beta . To name a few, dysregulation of transforming growth factor-beta signaling plays a role in carcinogenesis, autoimmunity, angiogenesis, and wound healing. In this report, we will review these clinical implications of transforming growth factor-beta .
authors.affiliation: Department of Urology, University of California at Irvine, Orange, CA 92868, USA.
authors.forename: Isaac Yi
authors.initials: IY
authors.lastname: Kim
authors.forename: Moses M
authors.initials: MM
authors.lastname: Kim
authors.forename: Seong-Jin
authors.initials: SJ
authors.lastname: Kim
mesh_terms: D001695:Biology; D006801:Humans; D016212:Transforming Growth Factor beta / Q000502:physiology*
chemical_list: D016212:Transforming Growth Factor beta