title: A giant subcutaneous leiomyosarcoma arising in the inguinal region.
abstract: BACKGROUND: Subcutaneous leiomyosarcoma is a rare condition that accounts for 1% to 2% of all superficial soft tissue malignancies. Approximately 10% of cases arise in the trunk, although the extremities are the most commonly affected. CASE PRESENTATION: We report herein the case of a 31-year-old man with a subcutaneous leiomyosarcoma, measuring 124 x 105 mm, arising in the left inguinal region. A wide local excision (with a resection margin >/= 20 mm) was performed. Histological examination of the resected specimen revealed a leiomyosarcoma with high cellularity and two mitoses per 10 high-power fields. The patient remains well with no evidence of disease 5 years and 8 months after the operation. CONCLUSION: This is the first reported case of subcutaneous leiomyosarcoma arising in the inguinal region and also one of the largest tumors reported. The experience of this case and a review of the English-language literature (PubMed, National Library of Medicine, Bethesda, MD, USA) suggest that a resection margin of >/= 10 mm is recommended when excising this rare tumor.
authors.affiliation: Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata City, 951-8510 Japan. shiray@med.niigata-u.ac.jp.
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Yajima
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Shirai
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Fujita
authors.forename: Daisuke
authors.initials: D
authors.lastname: Sato
authors.forename: Hajime
authors.initials: H
authors.lastname: Umezu
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Hatakeyama
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