title: Can large B-cell lymphoma mimic cystic lesions of the spleen?
abstract: A 58-yr-old male with a history of hepatitis C virus infection, presented with a 2-mo history of intractable left upper abdominal pain. He had fallen from a ladder 2 yr previously, landing on his left side. Abdominal computed tomography identified a large cystic mass in the spleen. The patient was brought to the operating room with a presumptive diagnosis of symptomatic, post-traumatic, false cyst of the spleen. Instead, at surgery, a splenic mass with dense adhesions to the diaphragm and stomach was found. On final histological analysis, it was diagnosed to be a large B-cell lymphoma. Despite its rarity, gastroenterologists and surgeons should be aware of large B-cell lymphoma when encountering cystic lesions of the spleen, because the management of benign cystic disease is usually nonsurgical.
authors.affiliation: Department of Surgery, Department of Radiology, University of California San Diego, San Diego, CA 92103, USA. ktakabe@ucsd.edu
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Takabe
authors.forename: Waddah
authors.initials: W
authors.lastname: Al-Refaie
authors.forename: Brian
authors.initials: B
authors.lastname: Chin
authors.forename: Pauline K
authors.initials: PK
authors.lastname: Chu
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Baird
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Blair
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D003560:Cysts / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D006526:Hepatitis C / Q000150:complications; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D013158:Splenic Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013160:Splenic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery
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