title: [Severe blunt liver injury: reappraisal of criteria for nonoperative management decision. Experience with 88 cases].
abstract: OBJECTIVE
  To analyze the predictive value of computed tomography (CT) and initial physiologic and laboratory data findings in the immediate operative (OP) or non-operative (NOP) management of blunt liver injury (BL).
  
  
  METHODS
  Eighty-eight BL, grade III (51), grade IV (28) and nine grade V (9), aged 26.2 years (16-75) were identified. Hemoperitoneum on CT, hemodynamic status, physiologic and laboratory data <24 hours or preoperative (transfusion, vascular filling) and follow-up >48 hours were analyzed.
  
  
  RESULTS
  Data of 71/88 (80%) NOP and 17/88 (20%) OP patients were reviewed. A secondary laparotomy or laparoscopy was necessary in 11/71 TNO. Six OP (35%) and 1 NOP patients died. Blood units transfused were 1.33 (0-10) vs 5.9 (0-22) and vascular filling 1.45 (0.5-5.5) vs 3.6L (2-12) (P<10(-6), P<4.10(-3) respectively). NOP patients had less severe hemoperitoneum (31 vs 94%, P<10(-5)) and hemodynamic instability (8.5 vs 94%, P<10(-4)). But, there was an overlap of values of blood units transfused, amount of vascular filling and initial haemoglobin levels between NOP and OP patients and among CT grades of liver injury. No cut-off values could be determined: 33% NOP received >4 blood units and >3 L vascular filling; 30% had severe hemoperitoneum. In OP group 23.5% patients had lower values and no severe hemoperitoneum.
  
  
  CONCLUSIONS
  In the management of BL, vascular filling and blood transfusion increased with the grade of CT liver injury and were globally more elevated in the operative group but did not individually correlate with hemodynamic stability and did not authorize, by themselves, to decide between operative versus non-operative management.
authors.affiliation: Service de chirurgie digestive et transplantation, CHRU, 59037 Lille cedex, France. frpruvot@chru-lille.fr
authors.forename: F R
authors.initials: FR
authors.lastname: Pruvot
authors.forename: F
authors.initials: F
authors.lastname: Meaux
authors.forename: S
authors.initials: S
authors.lastname: Truant
authors.forename: I
authors.initials: I
authors.lastname: Plénier
authors.forename: A
authors.initials: A
authors.lastname: Saudemont
authors.forename: L
authors.initials: L
authors.lastname: Gambiez
authors.forename: J-P
authors.initials: JP
authors.lastname: Triboulet
authors.forename: C
authors.initials: C
authors.lastname: Leroy
authors.forename: F
authors.initials: F
authors.lastname: Fourrier
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000465:Algorithms; D001803:Blood Transfusion; D003657:Decision Making; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000293:injuries*; D008297:Male; D008875:Middle Aged; D010347:Patient Care Planning; D011379:Prognosis; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed; D014949:Wounds, Nonpenetrating / Q000000981:diagnostic imaging / Q000628:therapy*
chemical_list: D006454:Hemoglobins