title: [Genotoxic risk of Goeckerman's therapy of psoriasis. Pilot study--children].
abstract: Goeckerman's therapy of psoriasis includes combined exposure to therapeutic tar and UV-B radiation. In a pilot study of (12 children) a level of genotoxic risk of the therapy was evaluated by chromosomal aberration of peripheral lymphocytes. Results of the pilot study suggest possible genotoxic risk of the therapy.
authors.affiliation: Univerzita Karlova v Praze, Lékarská fakulta v Hradci Králové: Ustav patologické fyziologie. borka@lfhk.cuni.cz
authors.forename: Lenka
authors.initials: L
authors.lastname: Borská
authors.forename: Zdenek
authors.initials: Z
authors.lastname: Fiala
authors.forename: Jindra
authors.initials: J
authors.lastname: Smejkalová
authors.forename: Kvetoslava
authors.initials: K
authors.lastname: Hamáková
authors.forename: Jan
authors.initials: J
authors.lastname: Kremlácek
mesh_terms: D000293:Adolescent; D002648:Child; D002869:Chromosome Aberrations; D003033:Coal Tar / Q000009:adverse effects*; D006801:Humans; D009152:Mutagenicity Tests; D010865:Pilot Projects; D011565:Psoriasis / Q000628:therapy*; D014467:Ultraviolet Therapy / Q000009:adverse effects*
chemical_list: D003033:Coal Tar