A pharmacokinetic-pharmacodynamic model for predicting tumour growth inhibition in mice: a useful tool in oncology drug development.
Rocchetti
Maurizio
M
Preclinical Development, Nerviano Medical Sciences, Viale Pasteur 10, 20014 Nerviano, Milan, Italy. maurizio.rocchetti@nervianoms.com
Poggesi
Italo
I
Germani
Massimiliano
M
Fiorentini
Francesco
F
Pellizzoni
Cinzia
C
Zugnoni
Paola
P
Pesenti
Enrico
E
Simeoni
Monica
M
De Nicolao
Giuseppe
G
D000818:Animals; D000970:Antineoplastic Agents / Q000493:pharmacokinetics* / Q000494:pharmacology; D015195:Drug Design; D006801:Humans; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000188:drug therapy* / Q000473:pathology; D012107:Research Design; D014183:Transplantation, Heterologous
D000970:Antineoplastic Agents