[Genetic polymorphism of D1S1612 and D18S535 in Chinese Han population of Beijing].
To investigate the genetic polymorphism of D1S1612 and D18S535 in Han population of Beijing. Amp-FLP method was used. 9 alleles, 25 genotypes were observed for D1S1612 locus; and 9 alleles and 27 genotypes for D18S535 locus. All allele frequencies, heterozygosity (H), discrimination power (Dp), exclusion of paternity probability (PE) and polymorphism information content (PIC) were calculated. The allele distributions of the two loci were conformed to Hardy-Weinberg equilibrium (P>0.01). According to the results obtained in this study, it is suggested that both D1S1612 and D18S535 are useful genetic markers for individual identification and paternity testing in forensic science practice as well for genetic study.
Pei
Li
L
Institute of Forensic Science, Ministry of Public Security, Beijing, 100038, China. PL128@sina.com.cn
Kong
Ming-Hua
MH
Cong
Bin
B
Li
Ji-Zhou
JZ
Jiang
Zhi-Lian
ZL
Wang
Li-Ming
LM
Ye
Jian
J
D000483:Alleles; D044466:Asian People / Q000235:genetics*; D002681:China / Q000208:ethnology; D005554:Forensic Medicine; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D005838:Genotype; D006579:Heterozygote; D006801:Humans; D018895:Microsatellite Repeats; D010334:Paternity; D011110:Polymorphism, Genetic
D005819:Genetic Markers