title: Hyperkalemic cardiac arrest after cardiopulmonary bypass in a child with unsuspected duchenne muscular dystrophy.
abstract: Adverse reactions to volatile anesthetics and depolarizing muscle relaxants can occur in patients with Duchenne muscular dystrophy (DMD) resulting in acute rhabdomyolysis and hyperkalemia. We report a case of hyperkalemic cardiac arrest after cardiac surgery using cardiopulmonary bypass in a child with unsuspected DMD. Early diagnosis and management of hyperkalemia resulted in a successful outcome. Genetic testing confirmed the diagnosis of DMD. We recommend a thorough preoperative investigation, including creatine kinase estimation, in children with a history of unexplained motor delay.
authors.affiliation: *Department of Anesthesia and Critical Care Medicine, The Children's Hospital of Philadelphia; and †Department of Anesthesia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.
authors.forename: Aruna
authors.initials: A
authors.lastname: Nathan
authors.forename: Arjunan
authors.initials: A
authors.lastname: Ganesh
authors.forename: Rodolfo I
authors.initials: RI
authors.lastname: Godinez
authors.forename: Susan C
authors.initials: SC
authors.lastname: Nicolson
authors.forename: William J
authors.initials: WJ
authors.lastname: Greeley
mesh_terms: D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D002675:Child, Preschool; D003402:Creatine Kinase / Q000097:blood; D006323:Heart Arrest / Q000209:etiology*; D006801:Humans; D006947:Hyperkalemia / Q000209:etiology*; D008297:Male; D020388:Muscular Dystrophy, Duchenne / Q000150:complications*
chemical_list: D003402:Creatine Kinase
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