title: Chemical constituents of Murraya siamensis: three coumarins and their anti-tumor promoting effect.
abstract: Isolation and structure elucidation of three coumarins, murrayacoumarins A, B, and C, together with eight known coumarins, from the leaves of Murraya siamensis Craib collected in Thailand are described. Results of a primary screening of inhibitory effects of seven of these compounds on 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus early antigen activation in Raji cells are also presented.
authors.affiliation: Faculty of Pharmacy, Meijo University,Tempaku, Nagoya 468-8503, Japan.
authors.forename: Chihiro
authors.initials: C
authors.lastname: Ito
authors.forename: Masataka
authors.initials: M
authors.lastname: Itoigawa
authors.forename: Saori
authors.initials: S
authors.lastname: Onoda
authors.forename: Atsuko
authors.initials: A
authors.lastname: Hosokawa
authors.forename: Nijsiri
authors.initials: N
authors.lastname: Ruangrungsi
authors.forename: Toshimitsu
authors.initials: T
authors.lastname: Okuda
authors.forename: Harukuni
authors.initials: H
authors.lastname: Tokuda
authors.forename: Hoyoku
authors.initials: H
authors.lastname: Nishino
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Furukawa
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology*; D045744:Cell Line, Tumor; D003374:Coumarins / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D032101:Murraya / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry
chemical_list: D000970:Antineoplastic Agents; D003374:Coumarins