title: Surgical treatment of aortic abscess and fistula.
abstract: The formation of annular abscess and fistulous communication, the most devastating complication of destructive aortic valve endocarditis, requires extensive surgical débridement. Five men experienced destructive native aortic valve endocarditis in association with congestive heart failure (New York Heart Association functional class IV) and hemodynamic deterioration that developed from severe aortic regurgitation. To eradicate the aortic valve endocarditis, we performed (from July 1998 through November 2002) aortic annular skeletonization by dissecting all infectious and necrotic tissue within the abscess cavity and the fistula between the ventriculoarterial junction and the sinotubular junction. The completely resected annular area was covered with a glutaraldehyde-treated autologous pericardial patch that was sutured firmly to fibrous tissue, for a secure proximal anastomosis. Reconstruction of the aortic root was followed by implantation of a Freestyle stentless bioprosthesis, using the aortic root replacement technique. There were no deaths after surgery, nor is there record of a permanent complication due to a loss of conduction tissue. All 5 patients were in New York Heart Association functional class I or II during follow-up (range, 8-56 months). Echocardiography showed no signs of valve dysfunction, recurrent endocarditis, or fistulation. Annular skeletonization and reconstruction of the aortic annulus with glutaraldehyde-treated autologous pericardium permits radical removal of infected tissue and effective treatment of aortic annular abscess, with less risk of valve dehiscence from the fragile aortic annulus.
authors.affiliation: Department of Cardiovascular Surgery, Kosuyolu Heart and Research Hospital, Kosuyolu, 81020 Istanbul, Turkey. nbozbuga@kosuyolu.gov.tr
authors.forename: Nilgun
authors.initials: N
authors.lastname: Bozbuga
authors.forename: Vedat
authors.initials: V
authors.lastname: Erentug
authors.forename: Hasan Basri
authors.initials: HB
authors.lastname: Erdogan
authors.forename: Kaan
authors.initials: K
authors.lastname: Kirali
authors.forename: Hasan
authors.initials: H
authors.lastname: Ardal
authors.forename: Serpil
authors.initials: S
authors.lastname: Tas
authors.forename: Esat
authors.initials: E
authors.lastname: Akinci
authors.forename: Cevat
authors.initials: C
authors.lastname: Yakut
mesh_terms: D000038:Abscess / Q000150:complications / Q000382:microbiology / Q000601:surgery*; D000328:Adult; D001022:Aortic Valve Insufficiency / Q000150:complications / Q000382:microbiology / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000150:complications / Q000382:microbiology / Q000601:surgery*; D001228:Aspergillosis / Q000601:surgery; D001232:Aspergillus fumigatus; D003646:Debridement; D004697:Endocarditis, Bacterial / Q000150:complications / Q000382:microbiology / Q000601:surgery*; D005402:Fistula / Q000150:complications / Q000382:microbiology / Q000601:surgery*; D006333:Heart Failure / Q000209:etiology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D010496:Pericardium / Q000637:transplantation*; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000601:surgery; D013211:Staphylococcus aureus; D013212:Staphylococcus epidermidis
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