title: Detection of infectious colitis by 18F-fluorodeoxyglucose-positron emission tomography in a child receiving intensive care after cardiac surgery.
abstract: Pyrexia of unknown origin (PUO) and suspected focal infection/inflammation are challenging medical problems. Nuclear medicine methods using scintigraphy with (111)In- or (99m)Tc-labelled antibodies or (67)Ga-citrate have been validated for the diagnosis and detection of inflammatory processes. Recently, positron emission tomography (PET) with (18)F-fluorodeoxyglucose (FDG) has been described as a promising imaging method, especially for PUO. We report the use of FDG-PET in an 18-month-old boy that revealed unexpected infectious colitis after cardiac surgery. This case suggests that FDG-PET is a valuable tool for the detection of unknown inflammatory foci in childhood, especially when the time needed for examination and radiation exposure are to be considered.
authors.affiliation: Klinik für Strahlenheilkunde, Campus Virchow-Klinikum, Charité--Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany. juri.ruf@charite.de
authors.forename: Juri
authors.initials: J
authors.lastname: Ruf
authors.forename: Boris
authors.initials: B
authors.lastname: Griebenow
authors.forename: Brigitte
authors.initials: B
authors.lastname: Stiller
authors.forename: Nanette
authors.initials: N
authors.lastname: Sarioglu
authors.forename: Peter E
authors.initials: PE
authors.lastname: Lange
authors.forename: Holger
authors.initials: H
authors.lastname: Amthauer
mesh_terms: D006348:Cardiac Surgical Procedures; D003092:Colitis / Q000150:complications / Q000000981:diagnostic imaging*; D003113:Colonoscopy; D003422:Critical Care; D005335:Fever of Unknown Origin / Q000209:etiology; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007223:Infant; D008297:Male; D049268:Positron-Emission Tomography; D011183:Postoperative Complications; D019275:Radiopharmaceuticals; D014915:Whole-Body Counting
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
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