Thyroid function in haemochromatosis.
BACKGROUND
In hereditary haemochromatosis (HH), the thyroid gland is the site of substantial iron deposition. However, there have been relatively few reported cases of thyroid dysfunction in HH.


OBJECTIVE
To evaluate the prevalence of thyroid disorders in a large group of patients with HH.


METHODS
A variety of endocrine investigations were undertaken including thyroid function tests and thyroid antibody studies.


RESULTS
A total of 154 consecutive patients (123 male, 31 female) were studied. One case of primary hypothyroidism was identified, giving a prevalence of 0.6%. Subclinical hypothyroidism was identified in two females, giving a prevalence of 1.3%. Iatrogenic hypothyroidism was identified in two other cases. No case of hyperthyroidism was identified.


CONCLUSIONS
Thyroid dysfunction is an uncommon occurrence in patients with HH.
Murphy
M S
MS
Department of Endocrinology, South Infirmary, Victoria Hospital, Old Blackrock Road, Cork, Ireland.
Walsh
C H
CH
D000328:Adult; D000368:Aged; D005260:Female; D006432:Hemochromatosis / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013959:Thyroid Diseases / Q000150:complications*
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