Living-donor lobar lung transplantation for bronchiolitis obliterans after bone marrow transplantation.
We report a successful case of living-donor lobar lung transplantation (LDLLT) for severe bronchiolitis obliterans (BO) after bone marrow transplantation (BMT). The patient is a 29-year-old woman who underwent BMT because of aplastic anemia in 1995. In 1996, BO developed in the patient because of chronic graft-versus-host disease. In May 2000, a LDLLT was performed. Pulmonary function tests showed improvement of both vital capacity and forced expiratory volume in 1 second. At present, 91 months after BMT and 38 months after lung transplantation, the patient is in good health. LDLLT may offer a therapeutic option for the treatment of BO after BMT.
Sano
Yoshifumi
Y
Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan. ysano@md.okayama-u.ac.jp
Date
Hiroshi
H
Nagahiro
Itaru
I
Aoe
Motoi
M
Shimizu
Nobuyoshi
N
D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D001989:Bronchiolitis Obliterans / Q000209:etiology* / Q000601:surgery*; D005260:Female; D006801:Humans; D019520:Living Donors; D016040:Lung Transplantation / Q000379:methods