title: Laser in situ keratomileusis in a patient with presumed central cloudy corneal dystrophy of Francois.
abstract: OBJECTIVE
  To report a case of laser in situ keratomileusis (LASIK) surgery performed in a patient with likely central cloudy corneal dystrophy of Francois (CCDF).
  
  
  METHODS
  Observational case report.
  
  
  METHODS
  A 48-year-old woman with likely CCDF had myopic LASIK to establish monovision. Outcome measures included visual acuity, manifest refraction, and slit-lamp examination.
  
  
  RESULTS
  At 5-year follow-up, the patient had uncorrected visual acuity of 20/100, J1, in the right eye (OD) and 20/20 in the left eye (OS), consistent with monovision correction. Manifest refraction was -1.50 OD and -0.25 OS postoperatively; after retreatment at 1 year for regression, the left eye remained stable over the subsequent 4-year period. Slit-lamp examination revealed no progression of corneal opacities in either eye.
  
  
  CONCLUSIONS
  LASIK may be safe and effective in patients with CCDF. Further observations of a greater number of patients are required to confirm these findings.
authors.affiliation: Department of Ophthalmology and the Francis I. Proctor Foundation at the University of California San Francisco, California 94143, USA.
authors.forename: Ali
authors.initials: A
authors.lastname: Zaidi
authors.forename: Stephen D
authors.initials: SD
authors.lastname: McLeod
mesh_terms: D003317:Corneal Dystrophies, Hereditary / Q000601:surgery*; D003319:Corneal Stroma / Q000601:surgery*; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D012029:Refraction, Ocular; D013524:Surgical Flaps; D016896:Treatment Outcome; D014792:Visual Acuity