title: Use of plant protein hydrolysates for varicella virus production in serum-free medium.
abstract: Serum-free media containing no animal-derived components were assessed for their efficacy to produce live attenuated varicella virus. Serum-free medium containing an ultrafiltrate of soy protein acid hydrolysate and lipid resulted in a viral production yield comparable to media containing fetal bovine serum, indicating that varicella virus can be produced without the risk of contamination associated with the use of bovine serum.
authors.affiliation: College of Life and Environmental Sciences, Korea University, 136-713, Sungbuk-gu, Anam-dong 5-1, Seoul, Korea.
authors.forename: Bok-Hwan
authors.initials: BH
authors.lastname: Chun
authors.forename: Yong
authors.initials: Y
authors.lastname: Kwon Lee
authors.forename: Won-Gi
authors.initials: WG
authors.lastname: Bang
authors.forename: Namhyun
authors.initials: N
authors.lastname: Chung
mesh_terms: D002460:Cell Line; D016895:Culture Media, Serum-Free / Q000378:metabolism*; D014645:Herpesvirus 3, Human / Q000254:growth & development*; D006801:Humans; D008168:Lung / Q000378:metabolism* / Q000821:virology*; D011492:Protein Hydrolysates / Q000378:metabolism*; D013025:Glycine max / Q000378:metabolism; D014779:Virus Replication / Q000502:physiology*
chemical_list: D016895:Culture Media, Serum-Free; D011492:Protein Hydrolysates