title: [Participation of the neostriatum transmission system in automation of motor skills in dogs].
abstract: The study shows that, in spite of high criteria of performing inctrumental reflex, the ability to repeat the reflex performance, the increase in tonic component of the response, a dostinct diagonal pattern of posture readjustment, and the local (not diffuse) projection of the mass centre position upon tensoplatforms of anterior paws were only observed after a prolonged training that led to automation of the skill. The instrumental response automation effect could be obtained at once following a bilateral microinjection of carbacholine into the neostriatum. The same albeit a weaker effect could be obtained with bilateral microinjections of D2 Dopamine receptor blocking agent Raclopride into the neostriatum. Bilateral injections of Pyrenzepine yield an opposite result: an increase in the physical component of the response < a disorder in the diagonal pattern of posture readjustment, and a diffuse nature of projection of the mass centre position of anterior paws on tensoplatforms. Indirect efferent output of the neostriatum seems to play an important role in motor instrumental reflex as well as in the process of automation of the motor skill.
authors.forename: K B
authors.initials: KB
authors.lastname: Shapvalova
mesh_terms: D000818:Animals; D002217:Carbachol / Q000008:administration & dosage; D018679:Cholinergic Agonists / Q000008:administration & dosage; D004285:Dogs; D009048:Motor Skills / Q000187:drug effects / Q000502:physiology*; D018727:Muscarinic Antagonists / Q000008:administration & dosage; D017072:Neostriatum / Q000502:physiology*; D010890:Pirenzepine / Q000008:administration & dosage
chemical_list: D018679:Cholinergic Agonists; D018727:Muscarinic Antagonists; D010890:Pirenzepine; D002217:Carbachol