Intraoperative recording of sacral root nerve signals in humans.
Electroneurographic signals were intraoperatively recorded from the S3 sacral nerve root in two SCI patients. The aim of this study was to record afferent nerve signals in response to mechanical stimulation of the urinary bladder, rectum, and dermatome. Such signals could be used in an implantable neuroprosthesis to treat neurogenic detrusor overactivity. In both patients a neural response was recorded from the dermatome and the rectum, but from the bladder only in one patient. The results were consistent with results from animal and other human studies. Further studies are however, needed because the number of subjects investigated remains low.
Kurstjens
Mathijs
M
Center for Sensory-Motor Interaction (SMI), Department of Health Science and Technology [corrected] Aalborg University, Aalborg, Denmark. mku@hst.aau.dk
Rijkhoff
Nico J M
NJ
Borau
Albert
A
Rodríguez
Alfred
A
Vidal
Joan
J
Sinkjaer
Thomas
T
D000328:Adult; D017097:Electric Impedance; D004558:Electric Stimulation; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D012007:Rectum / Q000294:innervation; D012447:Sacrum / Q000294:innervation; D012815:Signal Processing, Computer-Assisted; D012867:Skin / Q000294:innervation; D013119:Spinal Cord Injuries / Q000503:physiopathology* / Q000601:surgery; D013126:Spinal Nerve Roots / Q000503:physiopathology* / Q000601:surgery*; D001743:Urinary Bladder / Q000294:innervation; D001750:Urinary Bladder, Neurogenic / Q000503:physiopathology