[Systolic ventricular dysfunction, a new marker of coronary artery disease in patients with aortic stenosis without previous myocardial infarction].
Identification of clinical factors associated with coronary artery disease could obviate the need for coronary angiography in selected patients with severe aortic stenosis. We studied 315 patients (68 [8] years) with severe aortic stenosis without previous infarction who underwent coronary angiography. In the univariate analysis, age (P = .001), dyslipidemia (P = .003), angina (P = .018), aortic gradient (P = .001) and reduced ejection fraction (P = .006) were predictors of coronary artery disease. After multivariate analysis, age (OR = 1.079, P = .01), ejection fraction < 40% (OR = 2.685, P = .02), angina (OR = 2.518, P = .04) and dyslipidemia (OR = 2.34, P = .008) were the factors independently associated with coronary artery disease. Left ventricular dysfunction correlated independently with the presence of coronary artery disease.
Pérez Cabeza
Alejandro I
AI
Servicio de Cardiología, Hospital Clínico Universitario Virgen de la Victoria, Málaga, España. alejandroipc@hotmail.com
Gómez Doblas
Juan J
JJ
Morcillo Hidalgo
Luis
L
Cabrera Bueno
Fernando
F
Jiménez Navarro
Manuel F
MF
López Salguero
Raúl
R
Rodríguez Bailón
Isabel
I
de Teresa Galván
Eduardo
E
D000368:Aged; D001024:Aortic Valve Stenosis / Q000150:complications* / Q000175:diagnosis; D003327:Coronary Disease / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D013599:Systole; D014463:Ultrasonography; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000209:etiology*