title: Carcinoma of the submandibular salivary glands with multiple metastases in a cat.
abstract: A 9-year-old neutered male domestic shorthair cat was presented because of coughing, dysphagia, and prostration. Examination revealed firm bilateral anterocervical swellings extensively adhered to the surrounding tissues. Anisocoria with left-side miosis was also evident. X-ray and ultrasound examinations along with a fine-needle aspiration biopsy were performed. Slides were stained with May-Grünwald Giemsa, and a diagnosis of salivary gland carcinoma was made. At surgery, the tumor was found to involve both submandibular salivary glands as well as adjacent lymph nodes and surrounding tissues. The cat was euthanized and necropsy was performed. The majority of tissues and organs examined histologically, including mandibular and retropharyngeal lymph nodes, soft palate, laryngopharynx and lungs, contained neoplastic cells whose appearance was consistent with adenocarcinoma. Bilateral salivary adenocarcinoma has not previously been reported in cats, and extensive metastases are rare.
authors.affiliation: Department f Veterinary Public Health, Unit of Pathology, Faculty of Veterinary Medicine, University of Messina, Messina, Italy. gmazzull@unime.it
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Mazzullo
authors.forename: Alessandra
authors.initials: A
authors.lastname: Sfacteria
authors.forename: Nicola
authors.initials: N
authors.lastname: Ianelli
authors.forename: Massimo
authors.initials: M
authors.lastname: De Majo
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Pennisi
mesh_terms: D000818:Animals; D018267:Carcinoma, Acinar Cell / Q000473:pathology / Q000556:secondary / Q000662:veterinary*; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D008297:Male; D013365:Submandibular Gland Neoplasms / Q000473:pathology / Q000662:veterinary*