New parameters for left ventricular function in atrial fibrillation: based on the relationship between RR interval and performance.
This study was designed to obtain new parameters representing left ventricular (LV) function independent of irregular RR intervals in atrial fibrillation (AF). AF patients were divided into Normal (n=9) and LV Dysfunction (n=9) groups. The relations between LV outflow peak ejection velocity (Vpe) and preceding (RR-1) or prepreceding RR intervals (RR-2) were obtained using logarithmic equations, from which the squared correlation coefficient (r2), slope, Vpe at RR-1 or RR-2=1 sec (Vpe-1), and the ratio of slope to Vpe-1 (Slope/Vpe-1) were calculated. Among the parameters between RR-1 and Vpe, Slope/Vpe-1 was higher in LV Dysfunction group than in Normal group (p=0.05). When only coordinates with RR-1 from 0.6 to 1 sec were included, Slope/Vpe-1 (p=0.001) was higher in LV Dysfunction group than in Normal group. Among the parameters between RR-2 and Vpe, Slope/Vpe-1, slope, and r2 were different between the two groups. In multivariate analysis, Slope/Vpe-1 between RR-2 and Vpe was only independent parameter. However, Slope/Vpe-1 between RR-1 and Vpe in the coordinates with RR-1 from 0.6 to 1 sec had the highest discriminating power. New parameters derived from the relations between RR intervals and LV performance might be useful to evaluate LV function quantitatively in AF.
Ko
Hong Sook
HS
Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea.
Kim
Chee Jeong
CJ
Ryu
Wang Seong
WS
D000367:Age Factors; D000368:Aged; D001281:Atrial Fibrillation / Q000378:metabolism*; D016279:Atrial Function, Left; D004452:Echocardiography; D018619:Echocardiography, Doppler, Pulsed; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000502:physiology; D006352:Heart Ventricles; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D015999:Multivariate Analysis; D009200:Myocardial Contraction; D009206:Myocardium / Q000473:pathology; D013997:Time Factors; D016277:Ventricular Function, Left
Heart. 2002 Aug;88(2):170-6
12117848
Am J Cardiol. 2001 Feb 1;87(3):342-6, A9
11165975
Circulation. 1978 Dec;58(6):1072-83
709763
Cardiovasc Res. 1984 Feb;18(2):80-98
6697341
Am J Cardiol. 1986 Mar 1;57(8):563-70
3953440
Int J Biomed Comput. 1988 Oct;23(1-2):57-68
3065248
Circ Res. 1990 Dec;67(6):1437-45
1700935
Am J Cardiol. 1992 Jun 15;69(19):1570-3
1598871
Circulation. 1992 Oct;86(4):1223-32
1382889
J Am Coll Cardiol. 1995 Nov 15;26(6):1516-21
7594079
Am J Cardiol. 1996 Dec 15;78(12):1433-6
8970422
J Am Soc Echocardiogr. 1997 Jan-Feb;10(1):67-71
9046495
Am J Cardiol. 1997 Sep 1;80(5):586-90
9294986
J Am Coll Cardiol. 1997 Oct;30(4):1039-45
9316536
Cardiovasc Res. 1998 Apr;38(1):82-90
9683909
Circulation. 1998 Oct 27;98(17):1762-8
9788831
Am J Cardiol. 1998 Dec 15;82(12):1496-500
9874054
Heart. 1999 Nov;82(5):575-80
10525512
Am J Cardiol. 2000 Jan 1;85(1):114-6, A9
11078251
J Korean Med Sci. 2002 Dec;17(6):743-8
12482995