title: Involvement of P1 adhesin in gliding motility of Mycoplasma pneumoniae as revealed by the inhibitory effects of antibody under optimized gliding conditions.
abstract: To examine the participation of P1 adhesin in gliding of Mycoplasma pneumoniae, we examined the effects of an anti-P1 monoclonal antibody on individual gliding mycoplasmas. The antibody reduced the gliding speed and removed the gliding cells from the glass over time in a concentration-dependent manner but had only a slight effect on nongliding cells, suggesting that the conformational changes of P1 adhesin and its displacement are involved in the gliding mechanism.
authors.affiliation: Department of Biology, Graduate School of Science, Osaka City University, Sumiyoshi-ku, Osaka 558-8585, Japan.
authors.forename: Shintaro
authors.initials: S
authors.lastname: Seto
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Kenri
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Tomiyama
authors.forename: Makoto
authors.initials: M
authors.lastname: Miyata
mesh_terms: D018829:Adhesins, Bacterial / Q000502:physiology*; D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D001422:Bacterial Adhesion / Q000502:physiology; D009068:Movement; D009177:Mycoplasma pneumoniae / Q000502:physiology*; D013997:Time Factors
chemical_list: D018829:Adhesins, Bacterial; D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; C035471:adhesin, Mycoplasma pneumoniae
references.citation: Microbiology. 2000 Jun;146 ( Pt 6):1311-20
references.pmid: 10846210
references.citation: Microbiology. 2004 Dec;150(Pt 12):4001-8
references.pmid: 15583153
references.citation: J Bacteriol. 2002 Apr;184(7):1827-31
references.pmid: 11889087
references.citation: J Med Microbiol. 2002 May;51(5):361-73
references.pmid: 11990488
references.citation: FEMS Microbiol Lett. 2002 Oct 8;215(2):285-9
references.pmid: 12399048
references.citation: J Bacteriol. 2003 Feb;185(3):1082-91
references.pmid: 12533484
references.citation: Mol Microbiol. 2004 Feb;51(4):917-24
references.pmid: 14763969
references.citation: J Bacteriol. 2004 Mar;186(5):1537-45
references.pmid: 14973017
references.citation: J Bacteriol. 2004 Jul;186(13):4254-61
references.pmid: 15205428
references.citation: J Bacteriol. 2004 Jul;186(13):4382-6
references.pmid: 15205441
references.citation: J Bacteriol. 2004 Oct;186(20):6944-55
references.pmid: 15466048
references.citation: Pathol Microbiol (Basel). 1968;32(6):321-6
references.pmid: 4892712
references.citation: J Bacteriol. 1977 Mar;129(3):1495-501
references.pmid: 14925
references.citation: Science. 1982 Apr 16;216(4543):313-5
references.pmid: 6801766
references.citation: Nature. 1982 Aug 19;298(5876):765-7
references.pmid: 7110314
references.citation: Gene. 1989 Oct 30;82(2):259-67
references.pmid: 2583522
references.citation: J Gen Microbiol. 1992 Mar;138(3):407-22
references.pmid: 1593256
references.citation: J Bacteriol. 1994 Feb;176(3):781-8
references.pmid: 8300531
references.citation: Microbiol Mol Biol Rev. 1998 Dec;62(4):1094-156
references.pmid: 9841667
references.citation: Microbiology. 1998 Nov;144 ( Pt 11):2971-8
references.pmid: 9846732
references.citation: J Bacteriol. 1999 Feb;181(4):1079-87
references.pmid: 9973332
references.citation: J Bacteriol. 2001 Mar;183(5):1621-30
references.pmid: 11160093