title: [Resistance of Mycobacterium tuberculosis to antituberculotic drugs in Czech Republic in 2003].
abstract: BACKGROUND
  The results of Mycobacterium tuberculosis susceptibility testing in 2003 were analysed in 568 (84%) pulmonary TB definite cases in the Czech Republic.
  
  
  RESULTS
  The resistance on antituberculotic drugs was detected in 4.9% of TB bacilli. Most frequently, resistance on one drug--isoniazid (1.8% of pulmonary TB definite cases) has been observed. Multidrug resistant TB was found in two cases in 2003.
  
  
  CONCLUSIONS
  The resistance of Mycobacteria was found significantly more often in foreign-born persons with pulmonary TB (25% of strains of TB bacilli were resistant on one or more AT drugs). Resistance on AT drugs was more frequent also in previously treated TB cases, especially if the relapse occurred after 3,5 years after finishing previous treatment.
authors.affiliation: I. klinika tuberkulózy a respiracních nemocí 1. LF UK a VFN, Praha. jhomolka@cesnet.cz
authors.forename: J
authors.initials: J
authors.lastname: Homolka
authors.forename: F
authors.initials: F
authors.lastname: Krejbich
authors.forename: M
authors.initials: M
authors.lastname: Havelková
mesh_terms: D000995:Antitubercular Agents / Q000494:pharmacology*; D018153:Czech Republic / Q000453:epidemiology; D024881:Drug Resistance, Bacterial; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D018088:Tuberculosis, Multidrug-Resistant / Q000453:epidemiology / Q000382:microbiology
chemical_list: D000995:Antitubercular Agents