title: [Sentinel lymph node concept in prostate cancer].
abstract: A sentinel node (SN) validation study using a radioactive tracer and back-up extended pelvic lymph node (LN) dissection was performed in 40 patients with non-metastatic prostate cancer (PCa). The results of the study were favorable with sensitivity, specificity, and accuracy of SN biopsies revealed 90%, 100% and 97.5%, respectively. Based on our promising results to date, we examined the utility of SN navigation surgery (SNNS) in patients with LN metastasis probability of 10% or less on Partin tables. Endoscopic mini-laparotomy surgery was applied to our SN biopsies in 9 patients with clinically localized PCa. SNs were successfully resected in 7 of these patients. Endoscopic minilaparotomy SNNS is a less invasive form of radical surgery for prostate cancer with accurate diagnosis of LN status.
authors.affiliation: Department of Integrative Cancer Therapy and Urology, Graduate School of Medical Science, Kanazawa University.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Egawa
authors.forename: Mamoru
authors.initials: M
authors.lastname: Fukuda
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Imao
authors.forename: Mikio
authors.initials: M
authors.lastname: Namiki
mesh_terms: D004724:Endoscopy; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D011468:Prostatectomy / Q000379:methods; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D012680:Sensitivity and Specificity; D021701:Sentinel Lymph Node Biopsy / Q000379:methods