title: Clinical characteristics of multiple sclerosis with early onset.
abstract: Clinical characteristics of multiple sclerosis with early onset are described. The evolution is frequently relapsing-remitting; compared to the adult form, the EDSS levels of 3, 4 and 6 are reached after a longer interval but at a lower age. Negative prognostic factors are: a short inter-attack interval, a high relapse rate, a relapsing-progressive course or the shift to the secondary progressive phase, and early accumulation of disability.
authors.affiliation: Centro Studi Sclerosi Multipla, Ospedale di Gallarate Via Pastori 4, 1-21013 Gallarate, Italy. centro.sm@libero.it
authors.forename: A
authors.initials: A
authors.lastname: Ghezzi
mesh_terms: D004185:Disability Evaluation; D018450:Disease Progression; D006801:Humans; D009103:Multiple Sclerosis / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D011379:Prognosis