title: [Experimental study on pharmacodynamical of Oxalis griffithii, a national medicine in Guizhou].
abstract: OBJECTIVE
  To study the on effects of anti-bacteria, anti-inflammatory and pyretolysis of Oxalis griffithii, it is possible safety.
  
  
  METHODS
  The mice model was established by xylene (auricle smear method) and carrageenin (injection under the aponeuroses) respectively, rat febrile model was builded by 2,4-dintrophenol injection, and observe the effects of anti-bacteria in vitro that contracted by Staph aureus, Escherichia, Shigella, Pseudomonas, Aeruginosa. The mice model of experiment study on urgent poison effects (injection under the aponeuroses).
  
  
  RESULTS
  It was found that the mouse ear edema induced by xylene, the increased vascular permeability caused by xylene were all significantly suppressed by Oxalis griffithii. At the same time, it could depressed the rat fervescence by 2,4-dinitrophenol. In addition, it has effect on fighting against Escherichia coli in cavum abdominis of mice. Oxalis griffithii hasn't canker affect.
  
  
  CONCLUSIONS
  These results suggested that Oxalis griffithii had the effects of antinflammatory, pyretolysis, and safety.
authors.affiliation: Traditional Chinese Medicine School of Zunyi, Zunyi 563004, China. SDX63911@163.com
authors.forename: De-xun
authors.initials: DX
authors.lastname: Song
authors.forename: Jian-zhong
authors.initials: JZ
authors.lastname: Dai
authors.forename: Xue-yu
authors.initials: XY
authors.lastname: Zhang
authors.forename: Kai-yong
authors.initials: KY
authors.lastname: Zhao
authors.forename: Ming-qiang
authors.initials: MQ
authors.lastname: Xu
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D002199:Capillary Permeability / Q000187:drug effects; D002351:Carrageenan; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D004927:Escherichia coli Infections / Q000188:drug therapy; D005260:Female; D005334:Fever / Q000188:drug therapy; D019684:Magnoliopsida / Q000737:chemistry*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D004365:Drugs, Chinese Herbal; D002351:Carrageenan