High incidence of the Beijing genotype among multidrug-resistant isolates of Mycobacterium tuberculosis in a tertiary care center in Mumbai, India.
We report a high frequency (35%) of the Beijing genotype among multidrug-resistant isolates recovered in and around Mumbai, India. Further restriction fragment-length polymorphism typing showed that these strains were closely related. We also report a high frequency of the Delhi genotype (31% of isolates). Our data indicate considerable ongoing transmission of multidrug-resistant Mycobacterium tuberculosis strains of the Beijing genotype in Mumbai.
Almeida
Deepak
D
Research Labs, P. D. Hinduja National Hospital and Medical Research Centre, Mahim, Mumbai, India. dr_amehta@hindujahospital.com
Rodrigues
Camilla
C
Ashavaid
Tester F
TF
Lalvani
Ajit
A
Udwadia
Zarir F
ZF
Mehta
Ajita
A
D000293:Adolescent; D000328:Adult; D000995:Antitubercular Agents / Q000494:pharmacology; D021901:DNA, Intergenic; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D005838:Genotype; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000235:genetics*; D014376:Tuberculosis / Q000453:epidemiology / Q000382:microbiology*
D000995:Antitubercular Agents; D021901:DNA, Intergenic