title: Immunolocalization of nerve growth factor (NGF) and its receptors (TrkA and p75LNGFR) in the reproductive organs of Shiba goats.
abstract: The objective of this study was to determine the immunolocalization of NGF and its receptors (TrkA and p75LNGFR) in the reproductive tract of the Japanese Shiba goats. Five adult goats were used in this study and sections of ovaries, uteri and oviducts were immunostained by the avidin-biotin-peroxidase complex method (ABC). The results showed that NGF and its receptors (TrkA and p75LNGFR) were expressed in granulosa cells, theca cells, interstitial cells and lutein cells in ovaries. Immunoreactions for NGF, TrkA and p75LNGFR were also detectable in epithelial cells and muscle cells of the ampulla and isthmus of the oviduct, and in epithelial cells and uterine glands of the uterus. These results strongly suggest autocrine and paracrine regulation of reproductive function by NGF in the reproductive tract of female Shiba goats.
authors.affiliation: Department of Basic Veterinary Science, The United Graduate School of Veterinary Sciences, Gifu University, Japan.
authors.forename: LongQuan
authors.initials: L
authors.lastname: Ren
authors.forename: Mohamed S
authors.initials: MS
authors.lastname: Medan
authors.forename: Qiang
authors.initials: Q
authors.lastname: Weng
authors.forename: Wanzhu
authors.initials: W
authors.lastname: Jin
authors.forename: ChunMei
authors.initials: C
authors.lastname: Li
authors.forename: Gen
authors.initials: G
authors.lastname: Watanabe
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Taya
mesh_terms: D000818:Animals; D005187:Fallopian Tubes / Q000737:chemistry / Q000166:cytology / Q000378:metabolism*; D005260:Female; D005498:Follicular Phase; D006041:Goats / Q000033:anatomy & histology / Q000378:metabolism*; D007150:Immunohistochemistry; D020932:Nerve Growth Factor / Q000032:analysis; D010053:Ovary / Q000737:chemistry / Q000166:cytology / Q000378:metabolism*; D020917:Receptor, trkA / Q000032:analysis; D017475:Receptors, Nerve Growth Factor / Q000032:analysis; D014599:Uterus / Q000737:chemistry / Q000166:cytology / Q000378:metabolism*
chemical_list: D017475:Receptors, Nerve Growth Factor; D020932:Nerve Growth Factor; D020917:Receptor, trkA