An unusual case with relapsing neuromyelitis optica associated with undifferentiated connective tissue disease.
A case is presented with attacks of optic neuritis followed by severe myelitis 15 years later, in coincidence with a severe stressful life event. This female patient was also affected by undifferentiated connective tissue disease. This case presents some unusual and atypical findings such as: the association of a relapsing neuromyelitis optica with an undifferentiated connective tissue disease, a very long interval between optic neuritis and myelitis, and the important role of a stressful event in developing a relapse.
Protti
A
A
Unità Operativa Neurologia, Ospedale di Niguarda, Milan, Italy.
Erminio
C
C
Piccolo
I
I
Spreafico
C
C
Colombo
F
F
Ghezzi
A
A
D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008875:Middle Aged; D008947:Mixed Connective Tissue Disease / Q000134:cerebrospinal fluid / Q000150:complications* / Q000473:pathology; D009471:Neuromyelitis Optica / Q000134:cerebrospinal fluid / Q000150:complications* / Q000473:pathology; D013116:Spinal Cord / Q000473:pathology