Aggregation behaviors of gemini nucleotide at the air-water interface and in solutions induced by adenine-uracil interaction.
Cationic gemini surfactants having nucleotides as counterions (called nucleo-gemini hereafter) were synthesized and their aggregation behavior at air-water surfaces as well as in bulk solutions were studied. Fluid solutions of these nucleo-gemini surfactants show transitions to hydrogels upon addition of complementary nucleoside bases or other nucleo-gemini surfactants having complementary bases as counterions. The FTIR-ATR measurements show that the carboxylate groups of uridine form hydrogen bonds with the amine groups of adenosine. The aggregation behavior was also confirmed at the air-water interface by Brewster angle microscopy as well as surface pressure measurements; the monolayer of a gemini nucleotide was observed to undergo a transition to multilayers when nucleosides with complementary bases were added into the subphase. Isotherm curves of surface pressure monitored in parallel show a decrease in molecular area upon addition of such nucleosides.
Wang
Yujie
Y
Institut Européen de Chimie et Biologie, 2 rue Robert Escarpit, 33607 Pessac Cedex, France.
Desbat
Bernard
B
Manet
Sabine
S
Aimé
Carole
C
Labrot
Thomas
T
Oda
Reiko
R
D000225:Adenine / Q000737:chemistry*; D000388:Air; D002412:Cations / Q000737:chemistry; D015394:Molecular Structure; D009711:Nucleotides / Q000138:chemical synthesis* / Q000737:chemistry; D010316:Particle Size; D012680:Sensitivity and Specificity; D012996:Solutions / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods; D013499:Surface Properties; D013501:Surface-Active Agents / Q000138:chemical synthesis* / Q000737:chemistry; D014498:Uracil / Q000737:chemistry*; D014867:Water / Q000737:chemistry
D002412:Cations; D009711:Nucleotides; D012996:Solutions; D013501:Surface-Active Agents; D014867:Water; D014498:Uracil; D000225:Adenine