title: A rare case of nasal glioma in the sphenoid sinus of an adult presenting with meningoencephalitis.
abstract: Nasal gliomas are rare embryologic development defects that commonly present shortly after birth. Very few cases have ever been reported in adults. Of those presenting in adult life, most were casual findings in patients with no symptoms. Rare localizations have been described in the nasopharynx, soft palate, orbital cave and scalp. We present an unusual case of a 56-year-old man who initially presented with meningoencephalitis and was found to have nasal glioma in the sphenoid sinus. Having discussed their embryology and histology, we conclude that MRI scanning is the preferred method of investigation. However, radiological evaluation preoperatively should not lead to any sense of security if no bony defect (and thus, the possibility of intracranial extension) is demonstrated. Extirpation via a functional surgical approach is the treatment of choice to prevent deformities in the facial bones. This can range from direct incision over the gliomata to removal transnasally by endoscopy or using a lateral rhinotomy approach depending on the location, size and involvement of the glioma.
authors.affiliation: Royal Sussex County Hospital, Brighton, UK. hanychau@hotmail.com
authors.forename: Ha Nguyen
authors.initials: HN
authors.lastname: Chau
authors.forename: Clare
authors.initials: C
authors.lastname: Hopkins
authors.forename: Anthony
authors.initials: A
authors.lastname: McGilligan
mesh_terms: D005910:Glioma / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D008590:Meningoencephalitis / Q000150:complications*; D008875:Middle Aged; D010254:Paranasal Sinus Diseases / Q000150:complications* / Q000175:diagnosis; D013101:Sphenoid Sinus
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