The synergistic activity of antibiotics combined with eight traditional Chinese medicines against two different strains of Staphylococcus aureus.
The ethanolic extracts of eight traditional Chinese medicines and four antibiotics were investigated for their combined effects on the resistance of Staphylococcus aureus (S. aureus) in vitro. Methicillin resistant S. aureus, which was isolated from patient and a standard strain, were used. Our results showed that there are differences in the effects of many combinations used on the standard strain and resistant strain of S. aureus. The ethanolic extracts of Isatis tinctoria, Scutellaria baicalensis and Rheum palmatum can improve the antimicrobial activity of four antibiotics we used.
Yang
Zai-Chang
ZC
Key Laboratory of Biomechanics & Tissue Engineering (Chongqing University), Ministry of Education Bioengineering College of Chongqing University, Chongqing 400044, PR China.
Wang
Bo-Chu
BC
Yang
Xiao-Sheng
XS
Wang
Qiang
Q
Ran
Liang
L
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004357:Drug Synergism; D004365:Drugs, Chinese Herbal; D008516:Medicine, Chinese Traditional; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D013211:Staphylococcus aureus / Q000145:classification / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D004365:Drugs, Chinese Herbal