Intraspinal clear-cell meningioma: case report and review of literature.
BACKGROUND
Intraspinal clear-cell meningioma (CCM) is a rare morphological variant of meningioma with only 16 documented cases. We report one case and review the literature regarding intraspinal CCM.


METHODS
A 2-year-old boy and a 2-month-old male infant presented with knee pain and leg weakness. Magnetic resonance imaging revealed an intradural extramedullary neoplasm at T10-L1. The patient underwent radical resection of the tumor. Pathology and immunohistochemical study demonstrated a CCM. Unfortunately, the patient had a recurrence 5 years after the operation.


CONCLUSIONS
Intraspinal CCMs are very uncommon tumors. They usually show aggressive behavior with local recurrence observed in slightly more than half of all patients. We recommend serial imaging studies every 3 to 6 months during the first several years, after which an annual imaging study should be performed for follow-up.
Liu
Pen-I
PI
Department of Medical Imaging, Kaoshiung Medical University, Chung-Ho Memorial Hospital, Kaoshiung City, Taiwan, R.O.C.
Liu
Gin-Chung
GC
Tsai
Kun-Bow
KB
Lin
Chih-Lung
CL
Hsu
Jui-Sheng
JS
D000367:Age Factors; D018771:Arthralgia / Q000209:etiology; D014408:Biomarkers, Tumor / Q000378:metabolism; D002675:Child, Preschool; D004388:Dura Mater / Q000473:pathology / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008159:Lumbar Vertebrae / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008579:Meningioma / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D018908:Muscle Weakness / Q000209:etiology; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis*; D019635:Neurosurgical Procedures; D013117:Spinal Cord Compression / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D013120:Spinal Cord Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D013346:Subarachnoid Space / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D016896:Treatment Outcome
D014408:Biomarkers, Tumor