title: Synthesis and characterization of fluorine-containing hydroxyapatite by a pH-cycling method.
abstract: Different fluorine-containing hydroxyapatite (FHA) powders were synthesized through a pH-cycling method by varying sodium fluoride (NaF) concentration in hydroxyapatite (HA) suspensions. The powders were then calcined at 1200 ( composite function)C for 1 h. Both uncalcined and calcined powders were characterized using X-ray diffraction (XRD), Fourier transform infra-red (FTIR), and F-electrode. It was discovered that fluorine incorporation increased with the fluorine content in the initial solution and the number of pH cycles employed. A relatively low fluorine incorporation efficiency, approximately 60%, was attained for most of the FHA samples, and it did not vary significantly after calcination. It was also revealed that the FHA particles produced by the pH-cycling method were inhomogeneous. They were a mixture of hydroxyapatite and F-rich apatite (or FA) particles. After calcination, however, these FHA particles were homogenized and became single phased FHA.
authors.affiliation: Department of Metallurgy and Materials Engineering, University of Connecticut, 97 North Eagleville Road, Box U-136, Storrs, CT, 06269-3136, USA.
authors.forename: H
authors.initials: H
authors.lastname: Qu
authors.forename: M
authors.initials: M
authors.lastname: Wei
mesh_terms: D018786:Bone Substitutes / Q000032:analysis / Q000737:chemistry*; D003460:Crystallization / Q000379:methods*; D017886:Durapatite / Q000032:analysis / Q000737:chemistry*; D005461:Fluorine / Q000032:analysis / Q000737:chemistry*; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D008422:Materials Testing; D011208:Powders; D012996:Solutions
chemical_list: D018786:Bone Substitutes; D011208:Powders; D012996:Solutions; D005461:Fluorine; D017886:Durapatite
references.citation: J Mater Sci Mater Med. 2002 Nov;13(11):1037-43
references.pmid: 15348173
references.citation: Caries Res. 1973;7(3):231-44
references.pmid: 4518169
references.citation: Biomaterials. 1999 Aug;20(15):1421-6
references.pmid: 10454014
references.citation: J Mater Sci Mater Med. 2002 Nov;13(11):1045-50
references.pmid: 15348174
references.citation: Bone. 2002 May;30(5):705-11
references.pmid: 11996908
references.citation: J Biomed Mater Res. 1998 Jan;39(1):141-52
references.pmid: 9429105