title: [Impaired lung function in patients with moderate chronic obstructive bronchitis].
abstract: VC, FVC, FEV1, FEV1/VC%, PEF, MEF25, MEF50, MEF75, TLC, TGV, RV, Raw, Rin, Rex, DLCO-SS, paO2 and paCO2 were determined in 22 patients with moderate chronic obstructive bronchitis (FEV1, 79-50% of the normal value). All the patients were found to have impaired bronchial patency, 90.9% of the patients had lung volume and capacity changes; pulmonary gas exchange dysfunction was present in 72.7%. Bronchial patency impairments were manifested by a decrease in FEV1, FEV1/VC%, PEF, MEF25, MEF50, MEF75, and an increase in Raw, Rin, Rex. Changes in the lung volumes and capacities appeared as higher RV, TGV, TLC, lower VC and FVC. Pulmonary gas exchange dysfunction showed up as a reduction in pO2 and DLCO-SS a reduction and an increase in paCO2. The magnitude of the functional changes observed in most patients was low. Significant and pronounced disorders were seen in one third of the patients.
authors.forename: V B
authors.initials: VB
authors.lastname: Nefedov
authors.forename: L A
authors.initials: LA
authors.lastname: Popova
authors.forename: E A
authors.initials: EA
authors.lastname: Shergina
mesh_terms: D000328:Adult; D000368:Aged; D001980:Bronchi / Q000503:physiopathology; D029481:Bronchitis, Chronic / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011659:Pulmonary Gas Exchange; D012129:Respiratory Function Tests; D013997:Time Factors