The Doppler-derived myocardial performance index is determined by both left ventricular systolic and diastolic function as well as by afterload and left ventricular mass.
OBJECTIVE
To investigate if the newly developed Doppler-derived myocardial performance index (MPI, also denoted TEI-index) is associated with variables reflecting both left ventricular (LV) systolic and diastolic function, as well as variables reflecting preload, afterload, and LV geometry.


METHODS
An echocardiographic examination including Doppler was carried out in 446 men aged 70 in a population-based survey (the ULSAM-study, Uppsala Longitudinal Study of Adult Men).


RESULTS
In multiple regression analysis, MPI was independently associated with ejection fraction (P < 0.001), E/A ratio (P < 0.001), total peripheral resistance index (P < 0.001), stroke volume to pulse pressure ratio (P < 0.02), stroke index (P < 0.01), and LV mass (P < 0.04), but not with heart rate or blood pressure.


CONCLUSIONS
The echocardiographically determined myocardial performance index is determined by both LV systolic and diastolic function as well as by afterload and left ventricular mass.
Lind
Lars
L
Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Andrén
Bertil
B
Arnlöv
Johan
J
D000368:Aged; D001794:Blood Pressure / Q000502:physiology; D001830:Body Surface Area; D002302:Cardiac Output / Q000502:physiology; D015331:Cohort Studies; D003971:Diastole; D015150:Echocardiography, Doppler; D004562:Electrocardiography; D006339:Heart Rate / Q000502:physiology; D006352:Heart Ventricles / Q000033:anatomy & histology*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009200:Myocardial Contraction / Q000502:physiology*; D011159:Population Surveillance; D013318:Stroke Volume / Q000502:physiology; D013599:Systole; D014655:Vascular Resistance / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*