title: Selecting B cells and plasma cells to memory.
abstract: Humoral immunity appears to be based on immunological memory provided by memory plasma cells, which secrete protective antibodies, and memory B cells, which react to antigen challenge by differentiating into plasma cells. How these differentiation pathways relate to each other, how cells are selected into these memory populations, and how these populations are maintained remains enigmatic.
authors.affiliation: University Hospital Berlin and Deutsches Rheumaforschungszentrum Berlin, 10098 Berlin, Germany. thomas.doerner@charite.de
authors.forename: Thomas
authors.initials: T
authors.lastname: Dörner
authors.forename: Andreas
authors.initials: A
authors.lastname: Radbruch
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D006801:Humans; D007156:Immunologic Memory; D010950:Plasma Cells / Q000276:immunology
references.citation: Science. 2002 Dec 13;298(5601):2199-202
references.pmid: 12481138
references.citation: Curr Opin Immunol. 2002 Aug;14(4):523-36
references.pmid: 12088689
references.citation: J Immunol. 2002 Aug 1;169(3):1277-82
references.pmid: 12133949
references.citation: Science. 2002 Sep 20;297(5589):2066-70
references.pmid: 12242446
references.citation: J Exp Med. 2005 Feb 21;201(4):545-54
references.pmid: 15710653
references.citation: J Exp Med. 2003 May 19;197(10):1233-44
references.pmid: 12756262
references.citation: Int Immunol. 1998 Nov;10(11):1703-11
references.pmid: 9846699
references.citation: Blood. 2004 Dec 1;104(12):3647-54
references.pmid: 15191950
references.citation: Blood. 2005 Feb 15;105(4):1614-21
references.pmid: 15507523