title: Effect of cirrhosis and liver transplantation on the gender difference in QT interval.
abstract: The effect of gender on the QT interval in patients with cirrhosis before and after liver transplantation and the relation between the QT interval and changes in gender hormones after liver transplantation were assessed. The study showed that (1) physiologic gender difference in the QTc interval is abolished in cirrhosis, and it is not restored after liver transplantation, and (2) gender hormone concentrations had no effect on the QTc interval.
authors.affiliation: Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
authors.forename: Adegboyega Q
authors.initials: AQ
authors.lastname: Adigun
authors.forename: Amar G
authors.initials: AG
authors.lastname: Pinto
authors.forename: David A
authors.initials: DA
authors.lastname: Flockhart
authors.forename: J Christopher
authors.initials: JC
authors.lastname: Gorski
authors.forename: Lang
authors.initials: L
authors.lastname: Li
authors.forename: Stephen D
authors.initials: SD
authors.lastname: Hall
authors.forename: Naga
authors.initials: N
authors.lastname: Chalasani
mesh_terms: D000293:Adolescent; D000328:Adult; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications* / Q000601:surgery*; D016031:Liver Transplantation; D008133:Long QT Syndrome / Q000150:complications* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors