title: Eustachian tube function before recurrence of otitis media with effusion.
abstract: OBJECTIVE
  To study the role of eustachian tube function in the development of recurrent otitis media with effusion (OME) in children treated with tympanostomy tubes for OME.
  
  
  METHODS
  Prospective cohort study.
  
  
  METHODS
  Three academic and general hospitals.
  
  
  METHODS
  Children aged 2 to 7 years with a first clinical episode of OME that persisted for at least 3 months; 136 (81%) of 168 eligible children participated. All children received tympanostomy tubes for bilateral OME at study entry.
  
  
  METHODS
  Recurrence of OME within 6 months of tube extrusion.
  
  
  RESULTS
  No statistically significant differences were present in eustachian tube function test results between ears that developed recurrent OME and those that did not. The difference in passive ventilatory function between ears with and without OME recurrence was 10 daPa (95% confidence interval, -24 to 43 daPa) for opening pressure and -3 daPa (95% confidence interval, -18 to 11 daPa) for closing pressure. The overall difference in the proportion of ears with and without OME recurrence that could not equilibrate positive and negative applied pressures was 12% (95% confidence interval, -2% to 26%). The proportions of ears with and without OME recurrence that induced negative pressure in the middle ear by forcefully sniffing were 22% and 31%, respectively (P = .75).
  
  
  CONCLUSIONS
  Measurement of ventilatory and protective eustachian tube function using the forced response test, the pressure equilibration test, and the sniff test has no value in predicting whether children have an increased risk of OME recurrence.
authors.affiliation: Department of Epidemiology, University Medical Centre Nijmegen, 6500 HB Nijmegen, the Netherlands.
authors.forename: Masja
authors.initials: M
authors.lastname: Straetemans
authors.forename: Niels
authors.initials: N
authors.lastname: van Heerbeek
authors.forename: Anne G M
authors.initials: AG
authors.lastname: Schilder
authors.forename: Ton
authors.initials: T
authors.lastname: Feuth
authors.forename: Ger T
authors.initials: GT
authors.lastname: Rijkers
authors.forename: Gerhard A
authors.initials: GA
authors.lastname: Zielhuis
mesh_terms: D002675:Child, Preschool; D005064:Eustachian Tube / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008876:Middle Ear Ventilation; D010034:Otitis Media with Effusion / Q000503:physiopathology*; D011446:Prospective Studies; D012008:Recurrence