title: [Pharmacological peculiarities and problems with older patients].
abstract: Because of demographic developments, the fraction of the German population over 65 years of age in the year 2025 will have risen to 20% and will continue to rise so that in 2030 this number will have doubled compared to today's numbers. This has a huge impact on the requirements for anaesthesiologic procedures. In addition to the frequent multi-morbidity in this age group, physiologic changes also occur in the elderly which have to be taken into consideration during the entire perioperative management of these patients. Renal, cardiovascular and hepatic function are impaired in many elderly patients. A major concern in addition to cardiovascular and operative complications is the postoperative cognitive dysfunction (POCD), not only because of its implications for the patient but also because of economical consequences. Regional anaesthesia has some benefits when compared to general anaesthesia as it leads to a reduction in thromboembolic and respiratory complications.
authors.affiliation: Klinik für Anästhesie und Intensivtherapie, Klinikum der Philipps-Universität, Marburg. kratz@mailer.uni-marburg.de
authors.forename: C D
authors.initials: CD
authors.lastname: Kratz
authors.forename: A
authors.initials: A
authors.lastname: Schleppers
authors.forename: T
authors.initials: T
authors.lastname: Iber
authors.forename: G
authors.initials: G
authors.lastname: Geldner
mesh_terms: D000368:Aged / Q000502:physiology*; D000701:Analgesics, Opioid / Q000009:adverse effects; D000758:Anesthesia / Q000009:adverse effects*; D000765:Anesthesia, Conduction; D000777:Anesthetics / Q000009:adverse effects*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects; D009125:Muscle Relaxants, Central / Q000009:adverse effects
chemical_list: D000701:Analgesics, Opioid; D000777:Anesthetics; D006993:Hypnotics and Sedatives; D009125:Muscle Relaxants, Central
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