Transplantation of cultured human neural stem cells in rabbits with experimental laser-induced damage to the retina.
Cultured neural stem/progenitor cells from human fetal brain were transplanted into the retrobulbar and suprachoroid space in rabbits with laser-induced damage to the retina. Transplanted cells survived, retained multipotent activity, migrated into the zone of injury, and stimulated reparation and regeneration in the traumatized retina.
Pak
N V
NV
Ghelmgolts Moscow Research Institute of Eye Diseases, Russian Ministry of Health, Moscow, Russia.
Podgornyi
O V
OV
Aleksandrova
M A
MA
Chentsova
E V
EV
Ivanov
A N
AN
Golubeva
O N
ON
Poltavtseva
R A
RA
Marey
M V
MV
Sukhikh
G T
GT
D000818:Animals; D005131:Eye Injuries / Q000601:surgery*; D006801:Humans; D007834:Lasers; D011817:Rabbits; D012160:Retina / Q000473:pathology* / Q000528:radiation effects; D033581:Stem Cell Transplantation / Q000379:methods*; D014183:Transplantation, Heterologous