title: [Progress in research on triptolide].
abstract: To further understand triptolide, this paper has introduced the pharmacology, pharmacokinetics, toxicity, the clinic application and semi-synthesis of triptolide on basis of importance and significant contents of reference which have been consulted in the past twenty years. Presently triptolide and Tripterygium wilfordii have been a hot spot of modernization of Chinese traditional medicine. It is very important to develop a new dosage form of high effect and low toxicity by making use of advanced technology according to its characteristics.
authors.affiliation: The Research Institute of Pharmaceutics, Huazhong University of Science and Technology, Wuhan 430074, China.
authors.forename: Ming-xing
authors.initials: MX
authors.lastname: Liu
authors.forename: Jing
authors.initials: J
authors.lastname: Dong
authors.forename: Ya-jiang
authors.initials: YJ
authors.lastname: Yang
authors.forename: Xiang-liang
authors.initials: XL
authors.lastname: Yang
authors.forename: Hui-bi
authors.initials: HB
authors.lastname: Xu
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D018906:Antineoplastic Agents, Alkylating / Q000494:pharmacology; D000988:Antispermatogenic Agents / Q000494:pharmacology; D004224:Diterpenes / Q000138:chemical synthesis / Q000302:isolation & purification / Q000494:pharmacology* / Q000633:toxicity; D004852:Epoxy Compounds; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D010616:Phenanthrenes / Q000302:isolation & purification / Q000494:pharmacology* / Q000633:toxicity; D029757:Tripterygium / Q000737:chemistry
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D018906:Antineoplastic Agents, Alkylating; D000988:Antispermatogenic Agents; D004224:Diterpenes; D004852:Epoxy Compounds; D007166:Immunosuppressive Agents; D010616:Phenanthrenes; C001899:triptolide; C035061:triptophenolide