[Mechanisms of adaptation to hypoxia in primary hypothyroidism].
The paper contains data concerning the stimulatory effect of subcompensated hypoxia on the function of thyroid gland. Hypoxia-mediated improvement of the state of functional respiratory system (FRS) affects the endocrine system that is a part of the regulatory chain of FRS. Compensation of hypoxic state that takes place in pathogenesis of thyroid gland hypofunction is the result of improved oxygen supply during adaptation to hypoxia. Optimisation of oxygen supply as the result of the improvement of FRS working organs leads to the increase in velocity of oxygen consumption by organism and can evidence about the increase of oxygen consumption by thyroid glands that promotes their secretory activity intensification.
Radziievs'ka
M P
MP
D000222:Adaptation, Physiological / Q000502:physiology*; D000328:Adult; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007037:Hypothyroidism / Q000378:metabolism / Q000503:physiopathology* / Q000628:therapy; D000860:Hypoxia / Q000503:physiopathology*; D010100:Oxygen / Q000378:metabolism; D015656:Respiratory Mechanics / Q000502:physiology; D012138:Respiratory Therapy / Q000379:methods; D013974:Thyroxine / Q000008:administration & dosage / Q000627:therapeutic use
D013974:Thyroxine; D010100:Oxygen