title: Highly enantioselective dynamic kinetic resolution and desymmetrization processes by cyclocondensation of chiral aminoalcohols with racemic or prochiral delta-oxoacid derivatives.
abstract: Cyclocondensation reactions of aminoalcohols and with racemic or prochiral delta-oxoacid derivatives provide polysubstituted lactams with high enantioselectivity in a process that involves dynamic kinetic resolution and/or desymmetrization of enantiotopic or diastereotopic ester groups.
authors.affiliation: Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, 08028-Barcelona, Spain. amat@ub.edu
authors.forename: Mercedes
authors.initials: M
authors.lastname: Amat
authors.forename: Oriol
authors.initials: O
authors.lastname: Bassas
authors.forename: Miquel A
authors.initials: MA
authors.lastname: Pericàs
authors.forename: Mireia
authors.initials: M
authors.lastname: Pastó
authors.forename: Joan
authors.initials: J
authors.lastname: Bosch