title: [A clinical course of coronary heart disease after pacemaker implantation and optimization of the pacing regime].
abstract: OBJECTIVE
  To study effects of pacemaker implantation on the course of coronary heart disease (CHD) with stable angina pectoris and choice of optimal regimen of pacing.
  
  
  METHODS
  A total of 154 CHD patients with a pacemaker were examined. All the patients had angina of effort of functional class II-IV.
  
  
  RESULTS
  The symptoms of the disease improved in 72 (46.8%) patients (group 1): the number of anginal attacks decreased, exercise tolerance increased, the dose of antianginal medicines went down. Pain attacks became more frequent, response to nitroglycerin changed in 30 (19.5%) patients of group 2. This was explained by 1.5-2-fold enhancement of heart rate by pacemaker raising myocardial oxygen consumption and psychocardial syndrome. In 52 (33.8%) patients of group 3 anginal attacks characteristics did not change.
  
  
  CONCLUSIONS
  To optimize coronary reserve, frequency of electroimpulses must be reprogrammed to adjust to a functional class of angina and chronic cardiac failure as well as pacing regime. In particular, low coronary reserve demands optimal frequency of 55-65 imp/min while congenital cardiac failure--75-85 imp/min.
authors.forename: B G
authors.initials: BG
authors.lastname: Iskanderov
authors.forename: A A
authors.initials: AA
authors.lastname: Minkin
authors.forename: T N
authors.initials: TN
authors.lastname: Vakina
mesh_terms: D000787:Angina Pectoris / Q000628:therapy*; D002304:Cardiac Pacing, Artificial; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial