title: Aerobic oxidative amination of unactivated alkenes catalyzed by palladium.
abstract: The first examples of palladium-catalyzed oxidative amination of unactivated alkyl olefins have been identified. To be successful, these reactions must be conducted under cocatalyst-free conditions that involve direct dioxygen-coupled turnover of the palladium catalyst. The oxidative amination products of norbornene and other cyclic alkenes implicate a cis-aminopalladation mechanism.
authors.affiliation: Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706, USA.
authors.forename: Jodie L
authors.initials: JL
authors.lastname: Brice
authors.forename: Jenna E
authors.initials: JE
authors.lastname: Harang
authors.forename: Vitaliy I
authors.initials: VI
authors.lastname: Timokhin
authors.forename: Natia R
authors.initials: NR
authors.lastname: Anastasi
authors.forename: Shannon S
authors.initials: SS
authors.lastname: Stahl
mesh_terms: D000332:Aerobiosis; D000475:Alkenes / Q000737:chemistry*; D000586:Amination; D000588:Amines / Q000138:chemical synthesis*; D002384:Catalysis; D007097:Imines / Q000138:chemical synthesis*; D009636:Norbornanes / Q000737:chemistry; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry
chemical_list: D000475:Alkenes; D000588:Amines; D007097:Imines; D009636:Norbornanes; D010165:Palladium