title: Prebiopsy localisation of impalpable breast lesions.
abstract: Prebiopsy localization of impalpable breast lesions (IBL) assures removal of suspicious mammographically detected lesions. Specimen radiograph of the excised specimen is mandatory to confirm complete excision. The aim of this study was to audit our series of percutaneous hookwire localization and to determine the positive biopsy rate of the mammographically detected impalpable breast lesion in our center. Thirty-eight patients with suspicious IBL underwent excision biopsy under mammographic localization in our unit from late February 1998 to May 2003. The excised specimen is immobilized and compressed within the Transpec device. This device incorporates a reference grid visible in the specimen radiograph. Hence, the target lesion marked in the reference grid of the specimen radiograph will allow precise examination and exact localization of the suspicious lesion by the pathologist. The positive biopsy rate for malignant lesion was 26.3%, the majority fall in the range of 40-59 age group. Thirty-two (84.2%) of the patients had clustered micro-calcifications, 4 (10.5%) had impalpable mass lesions and in 2 (5.3%) spiculated lesions were seen on the preoperative mammogram. Mammographic feature of clustered micro-calcification accounts for all the malignant lesions in our series. Utilization of Transpec device has shown to be practical, reliable and cost effective in the management of IBL. Nonetheless, it should be emphasized that optimal specimen radiography and pathological correlation requires close cooperation between radiologist, surgeon and pathologist.
authors.affiliation: Department of Breast and Endocrine Surgery, Putrajaya Hospital, Precinct 7, 62250 Putrajaya, Malaysia.
authors.forename: A N
authors.initials: AN
authors.lastname: Hisham
authors.forename: K
authors.initials: K
authors.lastname: Harjit
authors.forename: O
authors.initials: O
authors.lastname: Fatimah
authors.forename: S I
authors.initials: SI
authors.lastname: Yun
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy / Q000379:methods* / Q000592:standards; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology; D004864:Equipment and Supplies / Q000592:standards*; D005260:Female; D006801:Humans; D008296:Malaysia; D008327:Mammography; D008875:Middle Aged; D015203:Reproducibility of Results