title: Epithelioid hemangioendothelioma of the nasal cavity.
abstract: Epithelioid hemangioendothelioma (EH) is an unusual vascular neoplasm characterized by proliferation of endothelial cells with epithelioid morphology. It has an indolent course, with the potential for recurrence, but rarely metastasizes. The common locations include soft tissue, skin, viscera and bone. We present an unusual case of EH in the nasal cavity and describe the clinical characteristics, histopathologic findings, differential diagnosis and management. The 25-year-old male patient initially presented with an 8-month history of intermittent epistaxis. Nasal endoscopy revealed a vascular tumor involving the nasal cavity. The tumor was excised and the final histopathologic diagnosis was consistent with EH. EH in the head and neck is extremely rare. Wide excision is the treatment of choice, and regular follow-up is suggested due to the potential for recurrence. Definitive diagnosis depends on histopathologic and immunohistochemical features.
authors.affiliation: Department of Otolaryngology, Taipei Veterans General Hospital, Taiwan, ROC.
authors.forename: Chih-Chieh
authors.initials: CC
authors.lastname: Tseng
authors.forename: Shyh-Haw
authors.initials: SH
authors.lastname: Tsay
authors.forename: Tung-Lung
authors.initials: TL
authors.lastname: Tsai
authors.forename: Chih-Hung
authors.initials: CH
authors.lastname: Shu
mesh_terms: D000328:Adult; D018952:Antigens, CD34 / Q000032:analysis; D003937:Diagnosis, Differential; D004844:Epistaxis / Q000209:etiology / Q000601:surgery; D018323:Hemangioendothelioma, Epithelioid / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009296:Nasal Cavity / Q000473:pathology* / Q000601:surgery; D009669:Nose Neoplasms / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D037121:Plant Lectins / Q000032:analysis; D016896:Treatment Outcome; D014841:von Willebrand Factor / Q000032:analysis
chemical_list: D018952:Antigens, CD34; D037121:Plant Lectins; C036850:Ulex europaeus lectins; D014841:von Willebrand Factor