title: [Behavioral, stress and immunological evaluation methods of music therapy in elderly patients with senile dementia].
abstract: The purpose of this study was to clarify the efficacy of behavioral, stress and immunological evaluation methods in music therapy (MT) with elderly patients with senile dementia. The MT group consisted of 8 elderly patients with dementia and the control group included 8 similarly matched patients. A total of 25 sessions of music therapy were conducted for one hour, twice each week for three months. The Mini-Mental State Exam (MMSE), Gottfries-Brane-Steen Scale (GBS), and Behavioral Pathology in Alzheimer's Disease Rating Scale (Behave-AD) were used to evaluate behavioral changes. Saliva Chromogranin A (Cg A) and Immunoglobulin A (Ig A) were used to assess changes in stress and immunological status, respectively. The results of the study were as follows: 1. In GBS, the mean score of "different symptoms common in dementia" improved significantly after MT. 2. The mean Behave-AD score of "paranoid and delusional ideation" was also significantly improved (p<0.05) after the intervention. 3. In the 25th session, mean saliva Cg A was significantly decreased after MT (p<0.05). IgA was slightly increased prior to intervention. Our results suggest that a combination of behavioral, stress and immunological evaluation methods were valuable for assessing changes that occurred during MT for elderly patients with dementia.
authors.affiliation: School of Nursing, Mie Prefectural College of Nursing.
authors.forename: Mizue
authors.initials: M
authors.lastname: Suzuki
authors.forename: Masao
authors.initials: M
authors.lastname: Kanamori
authors.forename: Shingo
authors.initials: S
authors.lastname: Nagasawa
authors.forename: Takayuki
authors.initials: T
authors.lastname: Saruhara
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000276:immunology / Q000628:therapy*; D001519:Behavior; D003704:Dementia / Q000276:immunology / Q000523:psychology / Q000628:therapy*; D015140:Dementia, Vascular / Q000276:immunology / Q000628:therapy; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis* / Q000097:blood; D008297:Male; D009147:Music Therapy; D011569:Psychiatric Status Rating Scales; D012463:Saliva / Q000737:chemistry; D013315:Stress, Psychological
chemical_list: D007070:Immunoglobulin A