title: Sudden re-opening of collapsed transverse sinuses and longstanding clinical remission after a single lumbar puncture in a case of idiopathic intracranial hypertension. Pathogenetic implications.
abstract: The aetiopathogenetic role of sinus venous obstructions carried by most idiopathic intracranial hypertension (IIH) patients is controversial. We report the case of a young woman diagnosed with IIH with papilloedema and narrowing of transverse sinuses, in which lowering of intracranial pressure by a single 20 ml cerebrospinal fluid (CSF) resulted in a strong dimensional increase of the transverse sinuses. Changes were followed by clinical remission and normalisation of optical nerve calibre, maintained after a 2-month follow-up. Our findings indicate that, although secondary to CSF hypertension, venous sinuses compression may have an important role in hypertensive status maintenance. Pathogenetic implications of venous sinus compression by hypertensive CSF in IIH are discussed.
authors.affiliation: Dipartimento di Scienze Neurologiche, Clinica Neurologica, Università di Napoli Federico II, Via S. Pansini 5, I-80131, Naples, Italy. rodesimo@unina.it
authors.forename: R
authors.initials: R
authors.lastname: De Simone
authors.forename: E
authors.initials: E
authors.lastname: Marano
authors.forename: C
authors.initials: C
authors.lastname: Fiorillo
authors.forename: F
authors.initials: F
authors.lastname: Briganti
authors.forename: F
authors.initials: F
authors.lastname: Di Salle
authors.forename: A
authors.initials: A
authors.lastname: Volpe
authors.forename: V
authors.initials: V
authors.lastname: Bonavita
mesh_terms: D000328:Adult; D003392:Cranial Sinuses / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D006801:Humans; D011559:Pseudotumor Cerebri / Q000628:therapy*; D011859:Radiography; D012074:Remission Induction; D013129:Spinal Puncture / Q000379:methods; D013995:Time