title: [Abdominal compartment syndrome: patophysiologic and clinic remarks].
abstract: The abdominal compartment syndrome is a high grade abdominal hypertension with clinical evidence of multiorgan failure (MOF). It is more and more frequently observed in intensive-care units as a complication in critical patients, but especially in traumatology and surgery. The incidence is highly variable according to the different trials but the severity of scores is the common factor. All the possible mechanical, haemorrhagical, inflammatory and traumatological causes act but do not enable the stability of the abdominal content, abdominal compliance and parietal tension. The initial triad of effects consists in diaphragm elevation and visceral and vascular compression and therefore triggers a physio-pathological way that leads to a respiratory, renal and cardiovascular dysfunction and to parietal, hepatic and intestinal ischaemia and consequent bacterial translocation: sepsis and MOF. Burch's classification (1996) reports four levels of gravity from low (<15 mmHg) to severe (>35 mmHg): both of the first grades should be managed in intensive-care units with conservative pharmacological procedures, while for the two others a surgical approach of laparotomy with drainage and temporaneous closure of the abdominal wall should be considered. As mortality is still very high (29-62%), especially when multiorgan failure is already set; bladder pressure of all critical patients should be monitorized to treat immediately any potential abdominal hypertension.
authors.affiliation: Università degli Studi La Sapienza--Roma, Istituto Dipartimentalizzato di Chirurgia d'Urgenza, Insegnamento di Chirurgia d'Urgenza.
authors.forename: F
authors.initials: F
authors.lastname: Stagnitti
authors.forename: S M
authors.initials: SM
authors.lastname: Calderale
authors.forename: F
authors.initials: F
authors.lastname: Priore
authors.forename: S
authors.initials: S
authors.lastname: Ribaldi
authors.forename: R
authors.initials: R
authors.lastname: Tiberi
authors.forename: M
authors.initials: M
authors.lastname: De Pascalis
authors.forename: F
authors.initials: F
authors.lastname: Corona
authors.forename: F
authors.initials: F
authors.lastname: Schillaci
authors.forename: A
authors.initials: A
authors.lastname: Costantini
authors.forename: P F
authors.initials: PF
authors.lastname: Salvi
mesh_terms: D000005:Abdomen / Q000503:physiopathology; D000007:Abdominal Injuries / Q000150:complications* / Q000601:surgery*; D003161:Compartment Syndromes / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D016638:Critical Illness; D004322:Drainage; D006801:Humans; D006973:Hypertension / Q000150:complications*; D007362:Intensive Care Units; D007813:Laparotomy; D008150:Lower Body Negative Pressure; D009102:Multiple Organ Failure / Q000209:etiology