title: Diffusion-weighted imaging with calculated apparent diffusion coefficient in intracranial hemorrhagic lesions.
abstract: In the literature published so far, measurement of values of the apparent diffusion coefficient (ADC) using an echo-planar imaging (EPI) technique in intracranial hemorrhagic lesions show no uniform results. Furthermore, no data exist for bleedings into intracranial lesions. We investigated the ADCs of 18 intracranial hemorrhagic lesions of different stages using echo-planar diffusion-weighted imaging (DWI). The ADC values measured in the hemorrhagic lesions ranged from 1.42 x 10(-3) to 0.22 x 10(-3) mm(2)/s. There were no significant differences between the ADC values in the hemorrhagic lesions and the contralateral white matter (P=.39). A differentiation between the lesions only with the ADC value was not possible as well. Using EPI DWI in intracranial hemorrhagic lesions of different stages, no reliable ADC values were found and a dependable differentiation between the lesions is not possible.
authors.affiliation: Department of Diagnostic Radiology, University Hospital of Regensburg, Franz-Josef-Strauss-Allee 11, D-93042 Regensburg, Germany. ulrich.dorenbeck@uniklinik-saarland.de
authors.forename: U
authors.initials: U
authors.lastname: Dorenbeck
authors.forename: J
authors.initials: J
authors.lastname: Schlaier
authors.forename: T
authors.initials: T
authors.lastname: Bretschneider
authors.forename: G
authors.initials: G
authors.lastname: Schuierer
authors.forename: S
authors.initials: S
authors.lastname: Feuerbach
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D017352:Echo-Planar Imaging; D005260:Female; D006801:Humans; D020300:Intracranial Hemorrhages / Q000473:pathology*; D008297:Male