Renal cell-to-cell communication via extracellular ATP.
In the kidney, macula densa cells communicate with the mesangial cell-afferent arteriolar smooth muscle cell complex through ATP signaling. This signaling process involves release of ATP across the macula densa basolateral membrane through a maxi anion channel and the interaction of ATP with purinergic P2 receptors.
Komlosi
Peter
P
Department of Medicine, Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama, USA. pkomlosi@uab.edu
Fintha
Attila
A
Bell
P Darwin
PD
D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D002450:Cell Communication / Q000502:physiology*; D005110:Extracellular Space / Q000378:metabolism; D006801:Humans; D007668:Kidney / Q000166:cytology* / Q000502:physiology*
D000255:Adenosine Triphosphate