Delayed emergence process does not result in a lower incidence of emergence agitation after sevoflurane anesthesia in children.
BACKGROUND
Emergence agitation (EA) is more frequent after sevoflurane anesthesia than other inhalational agents but the etiology remains unclear. We investigated whether the EA after sevoflurane anesthesia is related to rapid emergence.


METHODS
Eighty-five patients, aged 1-7 years, undergoing elective urology surgery were studied. After induction, anesthesia was maintained with 2.0-2.5% sevoflurane and 50% N(2)O. BIS was monitored continuously throughout surgery and emergence. At the end of surgery, the children were randomly assigned to one of two groups: group I, immediate cessation of sevoflurane; or group G, gradual decrease of sevoflurane with the rate of 0.1%.min(-1). Emergence agitation score was recorded during recovery.


RESULTS
Times from immediate cessation or start of decrease of sevoflurane to BIS 70, 80, 90 and extubation were significantly longer in group G. The incidence of severe agitation (score > or =3) was not significantly different between group I and group G: which were 35.7% and 32.6%, respectively.


CONCLUSIONS
Prolonged recovery did not reduce the incidence of EA following sevoflurane anesthesia in children.
Oh
A-Y
AY
Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul 110-744, Korea.
Seo
K-S
KS
Kim
S-D
SD
Kim
C-S
CS
Kim
H-S
HS
D000762:Anesthesia Recovery Period; D018685:Anesthetics, Inhalation / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography / Q000379:methods; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008738:Methyl Ethers / Q000009:adverse effects* / Q000627:therapeutic use; D011595:Psychomotor Agitation / Q000209:etiology / Q000517:prevention & control*; D012720:Severity of Illness Index; D000077149:Sevoflurane; D013997:Time Factors; D013520:Urologic Surgical Procedures / Q000379:methods
D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane