title: [Intra-articular treatment with Hylan G-F 20 under ultrasound guidance in hip osteoarthritis. Clinical results after 12 months follow-up].
abstract: Hip is a site very commonly affected by osteoarthritis (OA), yet few data exist in literature regarding intra-articular use of hyaluronic acid in this pathology. We evaluated the efficacy of Hylan G-F 20 hip viscosupplementation performed under ultrasound guidance. We enrolled 26 patients affected by symptomatic hip OA and treated them with a single intraarticular injection of Hylan G-F 20, which could be repeated every two months. The injection was performed under ultrasound guidance with an antero-superior approach. Treatment efficacy was assessed through Lequesne index, visual analogue scale (VAS) pain quantification, and NSAID intake at the timepoint zero (baseline), and after 2, 6 and 12 months. We observed a statistically significant reduction of all considered parameters at the timepoints 2 and 6 months, when compared to baseline. At 12 months the changes were still statistically significant for all parameters for about 50% of the patients. No side effect was observed, nor systemic complication. Viscosupplementation is a promising approach for hip OA, although further and wider studies are wanted to determine how long the beneficial effect lasts, and what is the optimal number of injections to administer.
authors.affiliation: Dipartimento di Medicina Interna, Ospedale S.Pietro-Fatebenefratelli, Via Cassia, 600-00192 Rome. alberto.migliore@tin.it
authors.forename: A
authors.initials: A
authors.lastname: Migliore
authors.forename: S
authors.initials: S
authors.lastname: Tormenta
authors.forename: C
authors.initials: C
authors.lastname: Valente
authors.forename: U
authors.initials: U
authors.lastname: Massafra
authors.forename: L S
authors.initials: LS
authors.lastname: Martin Martin
authors.forename: E
authors.initials: E
authors.lastname: Carmenini
authors.forename: A
authors.initials: A
authors.lastname: Bernardini
authors.forename: A
authors.initials: A
authors.lastname: Alimonti
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives*; D007270:Injections, Intra-Articular; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000000981:diagnostic imaging / Q000188:drug therapy*; D010865:Pilot Projects; D011446:Prospective Studies; D014463:Ultrasonography
chemical_list: C049816:hylan; D006820:Hyaluronic Acid