Extensive psoriasis induced by pegylated interferon alpha-2b treatment for chronic hepatitis B.
A 32-year-old man with chronic hepatitis B who was treated with pegylated interferon alpha-2b once a week, developed widespread psoriasis 4 weeks after the beginning of the treatment. There was no history of psoriasis. The treatment was stopped and gradually the eruption vanished. Thereafter, the patient was treated with lamivudine successfully without dermatological or other sequelae.
Ketikoglou
Ioannis
I
Department of Internal Medicine, Hippocration General Hospital, Athens, Greece. ketik@teledomenet.gr
Karatapanis
Stelios
S
Elefsiniotis
Ioannis
I
Kafiri
Georgia
G
Moulakakis
Antonios
A
D000328:Adult; D000998:Antiviral Agents / Q000009:adverse effects*; D019694:Hepatitis B, Chronic / Q000188:drug therapy*; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000009:adverse effects*; D008297:Male; D011092:Polyethylene Glycols; D011565:Psoriasis / Q000139:chemically induced* / Q000473:pathology; D011994:Recombinant Proteins
D000998:Antiviral Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D011092:Polyethylene Glycols; C417083:peginterferon alfa-2b