[Glucocorticoid-induced osteoporosis, up to date].
Glucocorticoid-induced osteoporosis (GIO) has been a hot topic in recent years. Glucocorticoids (GC) increase a fracture risk depending on the doses and affected especially vertebral bones. After cessation of GC, the fracture risk falls promptly, but does not reach at an equivalent level to non-medication. Moreover, a threshold of bone mineral densities predicting a fracture is higher in GIO than that in post-menopausal osteoporosis. Renewal of the management for GIO from UK is based on new knowledge. Risk factors other than bone mineral densities have been taken into consideration in renewing the management. An original management plan in Japan is expected coming soon. Further development of future research is needed.
Tanaka
Ikuko
I
Department of Biofunctional Research, National Institute for Longevity Sciences.