title: Vitamin K2 in bone metabolism and osteoporosis.
abstract: This article covers in vitro, in vivo, and human data on the positive effect of vitamin K2 on osteoporosis. Data is available on vitamin K2 for osteoporosis caused by a number of conditions, including postmenopausal osteoporosis, Parkinson's disease, biliary cirrhosis, stroke, and drug-induced osteoporosis. The activity of vitamin K2 involves both an increase in the bone-building process and a separate decrease in the bone-loss process. Vitamin K2 exerts a more powerful influence on bone than vitamin K1, and should be considered for prevention or treatment in those conditions known to contribute to osteoporosis.
authors.affiliation: Oncology Department, Bastyr University, Kenmore, Washington, USA.
authors.forename: Steven M
authors.initials: SM
authors.lastname: Plaza
authors.forename: Davis W
authors.initials: DW
authors.lastname: Lamson
mesh_terms: D000818:Animals; D001851:Bone Diseases, Metabolic / Q000209:etiology / Q000517:prevention & control; D004195:Disease Models, Animal; D006801:Humans; D010024:Osteoporosis / Q000188:drug therapy* / Q000517:prevention & control; D024482:Vitamin K 2 / Q000378:metabolism / Q000627:therapeutic use*
chemical_list: D024482:Vitamin K 2