title: Evaluation of left ventricular dimensions and function in Marfan's syndrome without significant valvular regurgitation.
abstract: Left ventricular dimensions and systolic function were studied using echocardiography in 234 patients with Marfan's syndrome without significant valvular regurgitation. Left ventricular dimensions and systolic function were found to be normal in most patients with Marfan's syndrome. Some involvement of the left ventricle may have been present in a small group of these patients. No patients, however, fulfilled the criteria for dilated cardiomyopathy.
authors.affiliation: Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: Lilian J
authors.initials: LJ
authors.lastname: Meijboom
authors.forename: Janneke
authors.initials: J
authors.lastname: Timmermans
authors.forename: Johan P
authors.initials: JP
authors.lastname: van Tintelen
authors.forename: Gijs J
authors.initials: GJ
authors.lastname: Nollen
authors.forename: Julie
authors.initials: J
authors.lastname: De Backer
authors.forename: Maarten P
authors.initials: MP
authors.lastname: van den Berg
authors.forename: Gerard H
authors.initials: GH
authors.lastname: Boers
authors.forename: Barbara J M
authors.initials: BJ
authors.lastname: Mulder
mesh_terms: D000293:Adolescent; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D001022:Aortic Valve Insufficiency / Q000175:diagnosis / Q000503:physiopathology; D002306:Cardiac Volume / Q000187:drug effects / Q000502:physiology*; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis / Q000503:physiopathology; D004452:Echocardiography / Q000187:drug effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008382:Marfan Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000503:physiopathology; D009200:Myocardial Contraction / Q000187:drug effects / Q000502:physiology; D016277:Ventricular Function, Left / Q000187:drug effects / Q000502:physiology*
chemical_list: D000319:Adrenergic beta-Antagonists