title: [Natural history of a suspicious renal mass in a patient with gastric cancer: how to evaluate the risk of multiple primary tumours (MPT)?].
abstract: The coexistence of several tumours in the same patient is a rare phenomenon and corresponds to the multiple primary tumour (MPT) syndrome. The most frequently diagnosed MPT include gastrointestinal tumours associated with urological tumours. Overexpression of the STAG1 gene could explain the development of several solid tumours and could be the origin of the multiple primary tumour syndrome. A suspicious renal mass discovered at the same time as a documented cancer is usually a malignant lesion and may justify combined radical surgical treatment. The authors report the natural history of a suspicious renal mass in a patient with primary gastric tumour corresponding to a MPT syndrome. They recall and discuss the epidemiology, pathophysiology, diagnosis and treatment of MPT.
authors.affiliation: Services d'Urologie-Transplantation, CHU d'Amiens, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Van Agt
authors.forename: Arnaud
authors.initials: A
authors.lastname: Bracq
authors.forename: Denis
authors.initials: D
authors.lastname: Chatelain
authors.forename: Marc
authors.initials: M
authors.lastname: Fourmarier
authors.forename: Jean Marc
authors.initials: JM
authors.lastname: Regimbeau
authors.forename: Pierre
authors.initials: P
authors.lastname: Verhaeghe
authors.forename: Jacques
authors.initials: J
authors.lastname: Petit
authors.forename: Fabien
authors.initials: F
authors.lastname: Saint
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D013274:Stomach Neoplasms / Q000175:diagnosis*