Two cases of retroperitoneal hematoma caused by combination of anticoagulant therapy and 5-fluorouracil.
We reported two cases of retroperitoneal hematoma in patients who received a combination of anticoagulant therapy and 5-fluorouracil (5-FU). We should be aware of the possible interaction of this combination therapy and monitor prothrombin time (PT) prolongation. CT is useful for evaluation of the disease.
Morita
Naomi
N
Department of Radiology, Ehime Prefectural Central Hospital, Ehime, Japan.
Kashihara
Kennichi
K
Tagashira
Hiroshi
H
Otsuka
Hideki
H
Yoneda
Kazuhide
K
Murase
Tomoya
T
Tsujikawa
Tetsuya
T
Furutani
Syunnsuke
S
Furutani
Kaori
K
Minato
Masako
M
Nishitani
Hiromu
H
D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects*; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000009:adverse effects; D003110:Colonic Neoplasms / Q000188:drug therapy; D004347:Drug Interactions; D004938:Esophageal Neoplasms / Q000188:drug therapy; D005472:Fluorouracil / Q000008:administration & dosage / Q000009:adverse effects*; D006406:Hematoma / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D012187:Retroperitoneal Space
D000925:Anticoagulants; D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil