title: [Multifocal tuberculosis with epididymitis and orchitis in an HIV negative patient].
abstract: This case report try to point out the importance of early diagnosis, and an appropriate treatment in multifocal tuberculosis including a testicular localization. A 25 year-old male with a past history of tuberculosis contact and untreated chronic cough with haemoptysis is admitted in our in-patient clinic. Eighteen months earlier, he presented a long course fever, with lumbar pain. Thereafter, the patient condition worsened as he lost weight and developed an enlargement of the right testicle with an scrotal abscess fistulous and a meningo-encephalitis clinical presentation. The bacilloscopy performed on gastric specimen and scrotal caseous was negative. The cerebrospinal fluid was clear and showed a mixed formula with 370 cells including 50% of lymphocytes, an elevated albumin (0.70g/l) and low glucose (0.10g/l) . Sterile pus was detected in urine. The tuberculosis skin test was positive. In addition to the clinical and epidemiological context, the radiological findings (chest and spine X-ray, testicular ultrasonography, cerebral CT Scan) were consistent with multifocal tuberculosis infection with lung miliary, epididymal-orchitis, and brain tuberculomas. The patient was treated successfully using a two-step protocol: two-month treatment with isoniazid, rifampicin, ethambutol and pyrazinamid altogether; followed by a seven-month regimen with isoniazid and rifampicin. Nevertheless,the patient is likely to develop static trouble and infertility because of the spine sequela and testicle atrophy he presented.
authors.affiliation: Clinique des Maladies infectieuses Ibrahima Diop Mar, CHU de Fann- Dakar. bmdiopmi@hotmail.com
authors.forename: B M
authors.initials: BM
authors.lastname: Diop
authors.forename: M
authors.initials: M
authors.lastname: Soumare
authors.forename: N M
authors.initials: NM
authors.lastname: Manga
authors.forename: E H
authors.initials: EH
authors.lastname: Niang
authors.forename: M
authors.initials: M
authors.lastname: Badiane
mesh_terms: D000328:Adult; D004823:Epididymitis / Q000382:microbiology*; D018023:HIV Seronegativity; D006801:Humans; D008297:Male; D009920:Orchitis / Q000382:microbiology*; D014376:Tuberculosis