title: Supramolecular modulation of action of polyamine on enzyme/DNA interactions.
abstract: Thread-in-hole complexation of cucurbit[6]uril (CB[6]) with spermidine and spermine either enhances or reduces the activity of the polyamine on the enzymatic reactions of DNA.
authors.affiliation: Department of Chemistry, The University of Tokyo, Hongo, Tokyo, 113-0033, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Isobe
authors.forename: Sota
authors.initials: S
authors.lastname: Sato
authors.forename: Jae Wook
authors.initials: JW
authors.lastname: Lee
authors.forename: Hee-Joon
authors.initials: HJ
authors.lastname: Kim
authors.forename: Kimoon
authors.initials: K
authors.lastname: Kim
authors.forename: Eiichi
authors.initials: E
authors.lastname: Nakamura
mesh_terms: D015317:Biogenic Polyamines / Q000737:chemistry* / Q000494:pharmacology; D001952:Bridged-Ring Compounds / Q000737:chemistry; D004247:DNA / Q000737:chemistry* / Q000187:drug effects; D004798:Enzymes / Q000737:chemistry* / Q000187:drug effects; D007093:Imidazoles / Q000737:chemistry; D015394:Molecular Structure; D013095:Spermidine / Q000737:chemistry / Q000494:pharmacology; D013096:Spermine / Q000737:chemistry / Q000494:pharmacology; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils
chemical_list: D015317:Biogenic Polyamines; D001952:Bridged-Ring Compounds; D004247:DNA; D004798:Enzymes; D007093:Imidazoles; D013095:Spermidine; D013096:Spermine; C454805:cucurbit(6)uril; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils