title: Report of altered sensation in patients with cleft lip.
abstract: OBJECTIVE
  To determine whether patients with cleft lip have normal perioral sensation.
  
  
  METHODS
  Each subject was carefully questioned about the following: sensation in the face at rest, light touch of different areas, and sensation in natural situations (e.g., exposure to cold weather) that reveal sensory abnormalities. A cotton-tip applicator stick was stroked lightly across the facial skin. The subject's descriptions of the evoked sensations were used to identify and outline areas with abnormal sensation.
  
  
  METHODS
  Data were obtained from subjects participating in a longitudinal, university-based study of the functional outcomes of lip revision surgery.
  
  
  METHODS
  Seventeen patients with cleft lip and 12 control subjects (aged 7 to 22 years, mean 12.9 years) participated.
  
  
  RESULTS
  In contrast to control subjects, 9 of 16 patients (56%) reported loss in sensation, described as decreased touch, scratch, tickle, or tingle intensity. Six other patients (38%) reported additional sensation, described as increased scratch, tickle, or tingle intensity. In eight patients, the altered sensation was restricted to the skin area flanking and including the visible scar, encompassing no more than 25% of the total area bound by the inferior nose, nasolabial grooves and inferior vermilion. In seven patients (unilateral cleft), the altered area extended to the contralateral, noncleft side of the upper lip or onto the philtrum.
  
  
  CONCLUSIONS
  In contrast to the literature, sensation in the upper lip of many patients with cleft lip is not normal. Loss in sensation is exhibited most commonly and limited largely to the skin overlying tissues traumatized during reconstructive surgery.
authors.affiliation: Department of Prosthodontics and Curriculum in Neurobiology, University of North Carolina, Chapel Hill, North Carolina 27599-7450, USA. greg_essick@dentistry.unc.edu
authors.forename: Greg K
authors.initials: GK
authors.lastname: Essick
authors.forename: Craig
authors.initials: C
authors.lastname: Dorion
authors.forename: Seth
authors.initials: S
authors.lastname: Rumley
authors.forename: Lyna
authors.initials: L
authors.lastname: Rogers
authors.forename: Michael
authors.initials: M
authors.lastname: Young
authors.forename: Carroll-Ann
authors.initials: CA
authors.lastname: Trotman
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002648:Child; D002971:Cleft Lip / Q000150:complications* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008046:Lip / Q000503:physiopathology; D008297:Male; D020886:Somatosensory Disorders / Q000209:etiology*; D013697:Thermosensing; D014110:Touch