[Osteoporosis and inflammatory bowel disease].
Inflammatory bowel disease is a chronic disease with an unknown ethiology although multiple factors intervene such as individual, genetic and immunologic susceptibility, as well as different environmental factors. Like other multisystemic diseases, its clinical manifestations are diverse and it may affect other organs besides the gastrointestinal tract. In the last few years there is a growing interest for one of these extraintestinal manifestations, osteoporosis and osteopenia that may affect up to 42% of patients and can condition an important increase in morbility. Inactivity, prolonged corticosteroid treatment, nutritional deficiencies and the disease per se have an important role in the development of this complication. This article reviews clinical and ethiological aspects of inflammatory bowel disease associated osteoporosis and offers a strategy for diagnosis and treatment.
Menchén
L
L
Servicio de Aparato Digestivo, Hospital General Universitario Gregorio Marañón, Madrid.
Ripoll
C
C
Bretón
I
I
Moreno
C
C
de la Cuerda
C
C
Camblor
M
M
García-Peris
P
P
González-Lara
V
V
Cos
E
E
D015502:Absorptiometry, Photon; D015519:Bone Density; D002986:Clinical Trials as Topic; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000150:complications* / Q000188:drug therapy; D010024:Osteoporosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*