title: Association of clinical and laboratory variables with ultrasound findings in right upper quadrant abdominal pain.
abstract: BACKGROUND
  The purpose of this study was to determine how laboratory values and physical examination findings correlate with ultrasound findings in the setting of right upper quadrant pain.
  
  
  METHODS
  Patients undergoing emergent ultrasound for the evaluation of biliary disease between November 1999 and April 2000 were included. Physical examination findings, laboratory data, and ultrasound results were variables. Logistic regression was performed. Ultrasound diagnosis of acute cholecystitis, cholelithiasis, and normal biliary tract were end points. One hundred seventy-seven patients were enrolled.
  
  
  RESULTS
  Forty-two percent were diagnosed with acute cholecystitis, 30.5% with cholelithiasis, and 27.1% with normal biliary tract. Alkaline phosphatase, Murphy sign, white blood cell count, and total bilirubin were statistically significant predictors of acute cholecystitis. A Murphy sign was defined as arrest of inspiration with pressure over the right upper quadrant.
  
  
  CONCLUSIONS
  The findings from this study allow clinicians to apply objective significance to laboratory data and physical examination findings in patients with suspected gallstone disease. The data can be applied to create a predictive model.
authors.affiliation: Division of Emergency Medicine, Louisiana State University at New Orleans, New Orleans, LA 70112, USA. LMORR1@lsuhsc.edu
authors.forename: Lisa D
authors.initials: LD
authors.lastname: Mills
authors.forename: Trevor
authors.initials: T
authors.lastname: Mills
authors.forename: Barbara
authors.initials: B
authors.lastname: Foster
mesh_terms: D015746:Abdominal Pain / Q000175:diagnosis* / Q000000981:diagnostic imaging; D002764:Cholecystitis / Q000175:diagnosis / Q000000981:diagnostic imaging; D002769:Cholelithiasis / Q000175:diagnosis / Q000000981:diagnostic imaging; D019411:Clinical Laboratory Techniques; D004636:Emergency Service, Hospital; D005260:Female; D006761:Hospitals; D006801:Humans; D016015:Logistic Models; D008297:Male; D010808:Physical Examination; D014463:Ultrasonography