title: Detection performance theory for ultrasound imaging systems.
abstract: A rigorous statistical theory for characterizing the performance of medical ultrasound systems for lesion detection tasks is developed. A design strategy for optimizing ultrasound systems should be to adjust parameters for maximum information content, which is obtained by maximizing the ideal observer performance. Then, given the radio-frequency data, image and signal processing algorithms are designed to extract as much diagnostically relevant information as possible. In this paper, closed-form and low-contrast approximations of ideal observer performance are derived for signal known statistically detection tasks. The accuracy of the approximations are tested by comparing with Monte Carlo techniques. A metric borrowed and modified from photon imaging, Generalized Noise Equivalent Quanta, is shown to be a useful and measurable target-independent figure of merit when adapted for ultrasound systems. This theory provides the potential to optimize design tradeoffs for detection tasks. For example it may help us understand how to push the limits of specific features, such as spatial resolution, without significantly compromising overall detection performance.
authors.affiliation: Department of Biomedical Engineering, University of California Davis, Davis, CA 95616, USA. rzemp@oilab.tamu.edu
authors.forename: Roger J
authors.initials: RJ
authors.lastname: Zemp
authors.forename: Mark D
authors.initials: MD
authors.lastname: Parry
authors.forename: Craig K
authors.initials: CK
authors.lastname: Abbey
authors.forename: Michael F
authors.initials: MF
authors.lastname: Insana
mesh_terms: D000465:Algorithms; D019985:Benchmarking / Q000379:methods; D003198:Computer Simulation; D017076:Computer-Aided Design; D004867:Equipment Design / Q000379:methods; D019544:Equipment Failure Analysis / Q000379:methods*; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008954:Models, Biological; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014463:Ultrasonography / Q000295:instrumentation* / Q000379:methods* / Q000592:standards