title: Malaria epidemic and drug resistance, Djibouti.
abstract: Analysis of Plasmodium falciparum isolates collected before, during, and after a 1999 malaria epidemic in Djibouti shows that, despite a high prevalence of resistance to chloroquine, the epidemic cannot be attributed to a sudden increase in drug resistance of local parasite populations.
authors.affiliation: IMTSSA-IFR48, BP46, Parc du Pharo, 13998 Marseille-Armees, France. christophe.rogier@wanadoo.fr
authors.forename: Christophe
authors.initials: C
authors.lastname: Rogier
authors.forename: Bruno
authors.initials: B
authors.lastname: Pradines
authors.forename: H
authors.initials: H
authors.lastname: Bogreau
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Koeck
authors.forename: Mohamed-Ali
authors.initials: MA
authors.lastname: Kamil
authors.forename: Odile
authors.initials: O
authors.lastname: Mercereau-Puijalon
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D016054:DNA, Protozoan / Q000737:chemistry / Q000235:genetics; D004196:Disease Outbreaks; D015730:Djibouti / Q000453:epidemiology; D004351:Drug Resistance / Q000235:genetics; D014644:Genetic Variation; D006239:Haplotypes; D006801:Humans; D016778:Malaria, Falciparum / Q000097:blood / Q000188:drug therapy / Q000453:epidemiology* / Q000469:parasitology*; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000302:isolation & purification; D017354:Point Mutation; D016133:Polymerase Chain Reaction
chemical_list: D000962:Antimalarials; D016054:DNA, Protozoan