[Treatment for osteoporosis with decreased bone formation].
Osteoporosis caused by aging, immobilization, and glucocorticoid excess involves impaired bone formation. Bisphosphonate, a potent inhibitor of bone resorption, has also been proven to be effective in their treatment. Human parathyroid Hormone (hPTH (1-34) ) has recently been shown to be an effective therapeutic agent for osteoporosis with its strong stimulatory action on bone formation, and has been approved by FDA for the treatment of osteoporosis. However, further studies will be necessary to solve the safety issues, especially in long-term treatment.
Ito
Yuji
Y
Department of Medicine and Bioregulatory Sciences, University of Tokushima, Graduate School of Medicine.
Kido
Shinsuke
S
Inoue
Daisuke
D