[Clinical observation of the lead discharging effect of paiqian chewing tablet].
OBJECTIVE
To observe the effect of paiqian chewing tablet (PQCT) on lead discharging and health in children.


METHODS
Adopting self-control and inter-group control method, 94 children with blood lead level exceeding 100 microg/L were randomly divided into the observed group and the control group. The observation period for both groups was 30 days.


RESULTS
At the 20th and 30th day of treatment, the urinary lead output in the observed group was significantly higher than that in the control group (P < 0.05, P < 0.01), and showed significant difference as compared with that before treatment (P < 0.05). Besides, the total amount of urinary lead discharging in the observed group was significantly more than that in the control group (P < 0.05).


CONCLUSIONS
PQCT has markedly lead discharging improvement action with no influence on urinary calcium and zinc excretion. As all the routine indexes of blood and urine ranged within the normal extent, it demonstrated that PQCT was harmless to the health of observed individual.
Lu
Jian-zhong
JZ
Center of Technology, Jiangzhong Pharmaceutical Co. Ltd., Nanchang 330077.
Cai
Yu
Y
Lu
Yi-bin
YB
Yu
Ping
P
Rao
Mei-xiang
MX
Zou
Hui
H
D002648:Child; D004311:Double-Blind Method; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007854:Lead / Q000097:blood / Q000652:urine; D007855:Lead Poisoning / Q000188:drug therapy*; D008297:Male; D008517:Phytotherapy; D013607:Tablets
D004365:Drugs, Chinese Herbal; D013607:Tablets; D007854:Lead