A clonal reciprocal t(2;7)(p13;p13) in plantar fibromatosis.
Cytogenetic reports of plantar fibromatosis are rare, and to our knowledge no clonal reciprocal translocations have been reported in these lesions. Reciprocal chromosome translocations have been identified in a number of solid tumors and in some cases have helped identify genes involved in their pathogenesis. We report a case of plantar fibromatosis with the novel finding of a t(2;7)(p13;p13) balanced reciprocal translocation as the sole cytogenetic abnormality.
Sawyer
Jeffrey R
JR
Department of Pathology, Cytogenetics Laboratory, University of Arkansas for Medical Sciences, Freeway Medical, Suite 200, 5800 West 10th Street, Little Rock, AR 72204, USA. sawyerjeffreyr@uams.edu
Sammartino
Gael
G
Gokden
Neriman
N
Nicholas
Richard W
RW
D000328:Adult; D002889:Chromosomes, Human, Pair 2; D002897:Chromosomes, Human, Pair 7; D005260:Female; D005350:Fibroma / Q000235:genetics*; D005528:Foot / Q000473:pathology*; D006801:Humans; D007621:Karyotyping; D014178:Translocation, Genetic