[Multiplicity in bone fragility].
Relative risk (RR) of vertebral fracture in anti-resorptive treatments has 25% reduction as the offset and then decreases 3% by every 1% increase in BMD. RR in non-vertebral fracture does not show the offset, but decreases 8 - 27% by every 1% increase in BMD. These reductions in fracture risk seem to be due to stabilization of trabecular bone structure by refilling of resorption pits and improvement of the material strength of bone tissue by the progress of secondary mineralization.
Nakamura
Toshitaka
T
Department of Orthopaedic Surgery, University of Occupational and Environmental Health.