Aspirin use during early pregnancy and the risk of congenital abnormalities: a population-based case-control study.
It is still controversial whether aspirin use during pregnancy increases the risk of certain congenital abnormalities (in particular, neural tube defects, gastroschisis, and cleft lip +/- palate). We examined the risk of selected congenital abnormalities in a large case-control dataset from Hungary and found no increased risk of such congenital abnormalities.
Nørgård
Bente
B
Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
Puhó
Erzsébet
E
Czeizel
Andrew E
AE
Skriver
Mette V
MV
Sørensen
Henrik T
HT
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D001241:Aspirin / Q000009:adverse effects*; D016022:Case-Control Studies; D002971:Cleft Lip / Q000139:chemically induced; D002972:Cleft Palate / Q000139:chemically induced; D005260:Female; D005333:Fetus / Q000187:drug effects; D020139:Gastroschisis / Q000139:chemically induced; D006801:Humans; D009436:Neural Tube Defects / Q000139:chemically induced; D011247:Pregnancy
D001241:Aspirin