title: [Sporadic cerebral amyloid angiopathy with ischemic leukoencephalopathy and microbleeds. Cause for a rapidly progressive dementia syndrome].
abstract: We describe a 72-year-old patient with rapidly progressive dementia and a complex focal seizure. Magnetic resonance (MR) imaging revealed leukoencephalopathy with the involvement of the U-fibers as well as cortical and subcortical microbleeds. Brain biopsy confirmed the diagnosis of cerebral Abeta amyloid angiopathy (CAA). The presented case illustrates the significance of CAA as a cause of rapidly progressive dementia and leukoencephalopathy and points out the importance of T2-weighted MR imaging in the evaluation of dementia.
authors.affiliation: Klinik für Neurologie, Universitätsmedizin Charité, Berlin. juri.katchanov@charite.de
authors.forename: J
authors.initials: J
authors.lastname: Katchanov
authors.forename: G
authors.initials: G
authors.lastname: Bohner
authors.forename: M
authors.initials: M
authors.lastname: Könneker
authors.forename: U
authors.initials: U
authors.lastname: Kopp
authors.forename: K
authors.initials: K
authors.lastname: Izadpanah
authors.forename: E
authors.initials: E
authors.lastname: Larmann
authors.forename: R
authors.initials: R
authors.lastname: Klingebiel
authors.forename: F
authors.initials: F
authors.lastname: van Landeghem
authors.forename: F
authors.initials: F
authors.lastname: Masuhr
authors.forename: R
authors.initials: R
authors.lastname: Zschenderlein
mesh_terms: D000368:Aged; D002545:Brain Ischemia / Q000150:complications / Q000175:diagnosis*; D016657:Cerebral Amyloid Angiopathy / Q000150:complications / Q000175:diagnosis*; D002543:Cerebral Hemorrhage / Q000150:complications / Q000175:diagnosis*; D003704:Dementia / Q000175:diagnosis* / Q000209:etiology; D018450:Disease Progression; D006801:Humans; D004684:Leukoencephalitis, Acute Hemorrhagic / Q000150:complications / Q000175:diagnosis*; D008297:Male; D013577:Syndrome