title: Toxicity of a dichlorvos containing insecticide formulation and an atrazine containing herbicide formulation in chicken embryos after individual administration.
abstract: A 50% dichlorvos containing insecticide formulation (Unifosz 50 EC) and a 50% atrazine containing herbicide formulation (Hungazin PK 50 WP) were studied in chicken embryos after administration as single compounds. Applied concentrations of dichlorvos were 0.1% (corresponding to the plant protection practice), 0.05%, 0.02%, 0.01%. Applied concentrations of atrazine were 0.66% (corresponding to the plant protection practice), 0.33%, 0.132%, 0.066%. The test materials were injected directly into the air-chamber of eggs on day 0 of the hatching period and evaulation was carried out on day 19 of incubation. The chicken embryos were examined for the following: rate of embryo mortality, body mass, type of developmental anomalies. After the single administrations of dichlorvos containing insecticide formulation and atrazine containing herbicide formulation on day 0 of incubation, the average body weight of chicken embryos significantly did not decrease as compared to the control. After the individual administrations of pesticides the incidence of developmental anomalies was sporadic. The embryonic mortality markedly increased at the highest concentrations of pesticides. The rate of embrio mortality were 61% (dichlorvos insecticide containing formulation) and 52% (atrazine containing herbicide formulation). In summary, the 50% dichlorvos containing insecide formulation (Unifosz 50 EC) and the 50% atrazine containing herbicide formulation (Hungazin PK 50 WP) were toxic to the developing chicken embryos at the highest concentration in our study. The toxic effect was expressed in the high rate of embrio mortality.
authors.affiliation: Department of Hygiene, Institute of Plant Protection, Georgikon Faculty of Agriculture University of Veszprém, H-8361 Keszthely, Hungary.
authors.forename: R
authors.initials: R
authors.lastname: Szabó
authors.forename: M
authors.initials: M
authors.lastname: Keseru
authors.forename: S
authors.initials: S
authors.lastname: Fejes
authors.forename: P
authors.initials: P
authors.lastname: Budai
authors.forename: E
authors.initials: E
authors.lastname: Juhász
authors.forename: A
authors.initials: A
authors.lastname: Pongrácz
mesh_terms: D000818:Animals; D001280:Atrazine / Q000633:toxicity*; D002642:Chick Embryo / Q000187:drug effects* / Q000502:physiology; D004006:Dichlorvos / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D006540:Herbicides / Q000633:toxicity*; D007306:Insecticides / Q000633:toxicity*; D009024:Morphogenesis / Q000187:drug effects
chemical_list: D006540:Herbicides; D007306:Insecticides; D004006:Dichlorvos; D001280:Atrazine