The pathogenesis and control of Staphylococcus aureus-induced mastitis: study models in the mouse.
The intramammary colonisation by Staphylococcus aureus provokes mastitis in the cow. Once established, the infection is difficult to eradicate with available therapies and may become chronic. The present article focuses on the use of the experimental mouse model of S. aureus-induced mastitis as a practical approach for the study of bovine mastitis. Results obtained regarding the pathogenesis of S. aureus and the development of new therapeutic approaches are discussed.
Brouillette
Eric
E
Centre d'étude et de valorisation de la diversité microbienne (CEVDM), Département de biologie, Faculté des sciences, Université de Sherbrooke, 2500 Boulevard Université, Sherbrooke, Que., Canada, J1K 2R1. eric.brouillette@sympatico.ca
Malouin
François
F
D000818:Animals; D002417:Cattle; D004195:Disease Models, Animal; D005260:Female; D008414:Mastitis, Bovine / Q000382:microbiology* / Q000503:physiopathology*; D051379:Mice; D013203:Staphylococcal Infections / Q000503:physiopathology*