title: Goal-directed therapy may improve outcome in complex patients--depending on the chosen treatment end point.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Frey
authors.forename: Duncan J
authors.initials: DJ
authors.lastname: Macrae
mesh_terms: D003362:Cost-Benefit Analysis; D003422:Critical Care; D016638:Critical Illness / Q000628:therapy*; D003657:Decision Making; D019317:Evidence-Based Medicine; D006302:Health Services Research; D006801:Humans; D016896:Treatment Outcome