S-nitrosothiol and S-nitrosoalbumin levels in pre-eclampsia plasma.
The aetiology of pre-eclampsia still eludes researchers. Recently, the development of laboratory techniques to measure the levels of serum nitrosothiols, compounds that appear to play a role in signal transduction and stress responses, could be the driving force in the search for the exact cause of pre-eclampsia. We attempted to verify a new technique of estimating the levels of S-nitrosothiols and S-nitrosoalbumin in pre-eclampsia. The laboratory technique used as described previously could not identify these compounds. None the less, these nitrosothiols and nitrosoalbumin may be involved in the aetiology of pre-eclampsia.
Moodley
J
J
Department of Obstetrics and Gynaecology, and MRC/UN Pregnancy Hypertension Research Unit, University of Natal, Congella 4013, South Africa. gynae@nu.ac.za
Gwababa
S S
SS
D000293:Adolescent; D000328:Adult; D002585:Cesarean Section / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D009603:Nitroso Compounds; D010298:Parity; D011225:Pre-Eclampsia / Q000097:blood* / Q000209:etiology; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology; D026403:S-Nitrosothiols / Q000097:blood*; D012710:Serum Albumin, Bovine / Q000032:analysis*
D009603:Nitroso Compounds; D026403:S-Nitrosothiols; C091665:S-nitrosoalbumin; D012710:Serum Albumin, Bovine