Diametrically disubstituted cyclam derivative having Hg2+-selective fluoroionophoric behaviors.
[reaction: see text] A new fluoroionophore has been synthesized by appending two signaling pyrenylacetamide subunits on the binding motif of 1,8-dimethylcyclam. The designed compound exhibited highly selective and sensitive fluoroionophoric behavior toward Hg(2+) ions of excimer emission in aqueous dioxane (dioxane/H(2)O = 1:9, v/v) solution with a detection limit of 1.3 x 10(-)(6) M. The "ON-OFF" type signaling behavior of the fluoroionophore is due to the metal ion induced conformational changes from folded to open-winged conformations by exploiting the two nearby appended pyrenyl fluorophores.
Moon
So-Youn
SY
Department of Chemistry, Chung-Ang University, Seoul 156-756, Korea.
Youn
Na Jin
NJ
Park
Sang Mi
SM
Chang
Suk-Kyu
SK
D005456:Fluorescent Dyes / Q000138:chemical synthesis*; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D008628:Mercury / Q000737:chemistry*; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000138:chemical synthesis*; D011721:Pyrenes / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013237:Stereoisomerism
D005456:Fluorescent Dyes; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; D011721:Pyrenes; C024560:cyclam; D008628:Mercury