[Uveitis in conjunction with rheumatological diseases in childhood].
Children with juvenile chronic arthritis are at risk to develop intraocular inflammation depending on the type of arthritis. The pathogenic mechanisms are unclear; however, an association with antinuclear antibodies is well known. In particular young girls with oligoarticular onset of arthritis are affected most often. Regular ophthalmologic examinations should allow early diagnosis and effective therapy. Complications such as synechiae, cataract, or macula edema are seen especially in uveitis patients with late diagnosis and insufficient anti-inflammatory therapy. Better therapeutic regimens have led to a better overall prognosis of intraocular inflammation in recent years.
Sengler
C
C
Klinik für Pädiatrie mit Schwerpunkt Pneumologie und Immunologie, Campus Virchow-Klinikum der Charité-Universitätsmedizin, Berlin.
Keitzer
R
R
Pleyer
U
U
D000367:Age Factors; D000818:Animals; D000974:Antibodies, Antinuclear / Q000032:analysis; D001171:Arthritis, Juvenile / Q000150:complications* / Q000276:immunology; D002386:Cataract / Q000209:etiology; D002648:Child; D002986:Clinical Trials as Topic; D003937:Diagnosis, Differential; D004195:Disease Models, Animal; D005260:Female; D005654:Fundus Oculi; D005901:Glaucoma / Q000209:etiology; D006801:Humans; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D025242:Spondylarthropathies / Q000150:complications; D013997:Time Factors; D014606:Uveitis, Anterior / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000276:immunology; D014786:Vision Disorders / Q000209:etiology; D014792:Visual Acuity
D000974:Antibodies, Antinuclear