title: Predictors of treatment failure among tuberculosis patients under DOTS strategy in Egypt.
abstract: Treatment failure is a serious problem facing some national tuberculosis (TB) control programmes. Irregularity of treatment is a factor that can lead to treatment failure. A case-control study was carried out in TB centres in Egypt during April 2001-December 2002 aimed at investigating the predictors of treatment failure. We interviewed 119 people with treatment failure and an equal number of cured cases (controls) and their families regarding sociodemographic characteristics, information about TB, information about drugs, treatment compliance, family support and patient-family interaction. Significant risk factors for treatment failure were non-compliance to treatment, deficient health education to the patient, poor patient knowledge regarding the disease and diabetes mellitus as co-morbid condition.
authors.affiliation: National Tuberculosis Control Programme, Ministry of Health and Population, Cairo, Egypt.
authors.forename: A M
authors.initials: AM
authors.lastname: Morsy
authors.forename: H H
authors.initials: HH
authors.lastname: Zaher
authors.forename: M H
authors.initials: MH
authors.lastname: Hassan
authors.forename: A
authors.initials: A
authors.lastname: Shouman
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D016022:Case-Control Studies; D015897:Comorbidity; D048909:Diabetes Complications / Q000150:complications / Q000453:epidemiology; D023801:Directly Observed Therapy / Q000379:methods / Q000523:psychology; D004522:Educational Status; D004534:Egypt / Q000453:epidemiology; D005190:Family / Q000523:psychology; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance / Q000523:psychology; D010353:Patient Education as Topic / Q000592:standards; D011237:Predictive Value of Tests; D015397:Program Evaluation; D012307:Risk Factors; D012944:Social Support; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D017211:Treatment Failure; D014376:Tuberculosis / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology / Q000523:psychology
chemical_list: D000995:Antitubercular Agents