title: Sugars inhibit expression of the rugose phenotype of Vibrio cholerae.
abstract: Vibrio cholerae can shift to a rugose colony phenotype, reflecting expression of an exopolysaccharide that provides protection against a variety of environmental stresses. Our data indicate that expression of the rugose phenotype is inhibited by a variety of sugars, including sucrose, dextrose, arabinose, fructose, and maltose. Inhibition by sucrose may be one factor in explaining the failure of rugose strains to grow on thiosulfate citrate bile salts sucrose agar, the primary selective medium for V. cholerae.
authors.affiliation: Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. aali@epi.umaryland.edu
authors.forename: Afsar
authors.initials: A
authors.lastname: Ali
authors.forename: J Glenn
authors.initials: JG
authors.lastname: Morris
authors.forename: Judith A
authors.initials: JA
authors.lastname: Johnson
mesh_terms: D002241:Carbohydrates / Q000494:pharmacology*; D003470:Culture Media; D006863:Hydrogen-Ion Concentration; D010641:Phenotype; D014734:Vibrio cholerae / Q000254:growth & development*
chemical_list: D002241:Carbohydrates; D003470:Culture Media