title: Perioperative monitoring of flow and patency in native and grafted internal mammary arteries using a combined MR protocol.
abstract: The objective of this study was to evaluate graft flow (f) and patency (p) in patients with internal mammary artery (f,p) and venous (p only) grafts using a combined MR protocol with phase-contrast technique and MR angiography. 42 patients with 42 left internal mammary artery (LIMA) and 63 venous grafts were examined pre and 6 months post coronary artery bypass graft (CABG) surgery. Phase-contrast flow measurements were applied to the IMA. Post-operatively, a contrast enhanced MR angiogram was performed to assess bypass patency. LIMA/venous grafts were occluded in 3/42 and 13/63, respectively. Flow in LIMA decreased from 19.4+/-10.4 ml min(-1) m(-2) pre-operatively to 13.4+/-9.7 ml min(-1) m(-2) post-operatively (p<0.002). In contrast, flow in the native right IMA increased from 17.6+/-8.7 ml min(-1) m(-2) pre-operatively to 24.8+/-9.0 ml min(-1) m(-2) post-operatively (p<0.001). MRI allows a combined assessment of bypass patency and flow. This study protocol may be applicable to perioperative follow-up studies in patients after CABG surgery.
authors.affiliation: Department of Diagnostic Radiology, Eberhard-Karls-University, Tübingen, Germany.
authors.forename: N I
authors.initials: NI
authors.lastname: Stauder
authors.forename: A M
authors.initials: AM
authors.lastname: Scheule
authors.forename: U
authors.initials: U
authors.lastname: Hahn
authors.forename: M
authors.initials: M
authors.lastname: Fenchel
authors.forename: F S
authors.initials: FS
authors.lastname: Eckstein
authors.forename: U
authors.initials: U
authors.lastname: Kramer
authors.forename: C D
authors.initials: CD
authors.lastname: Claussen
authors.forename: S
authors.initials: S
authors.lastname: Miller
mesh_terms: D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology; D003287:Contrast Media; D001026:Coronary Artery Bypass / Q000379:methods*; D003327:Coronary Disease / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D007387:Internal Mammary-Coronary Artery Anastomosis / Q000379:methods; D007430:Intraoperative Care / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods; D008297:Male; D008323:Mammary Arteries / Q000502:physiology; D008875:Middle Aged; D014654:Vascular Patency / Q000502:physiology
chemical_list: D003287:Contrast Media