title: High prevalence of substance use disorders among adolescents who use marijuana and inhalants.
abstract: BACKGROUND
  We examined the association between the use of inhalants, marijuana, and other drugs and recent DSM-IV substance use disorders among adolescents aged 12-17 years.
  
  
  METHODS
  Data were drawn from 2000 to 2001 National Household Surveys on Drug Abuse. Adolescents aged 12-17 years who reported having ever used an illicit drug in their lifetime were categorized into four mutually exclusive groups: inhalant users (16%), marijuana users (53%), inhalant and marijuana users (16%), and other drug users (15%). Logistic regression models were used to estimate associations with recent substance use diagnoses among lifetime adolescent drug users (N=10,180).
  
  
  RESULTS
  We found that 31% of lifetime drug users reported having never used marijuana. One half of these atypical drug users were predominantly nonmedical users of pain relievers. Adolescents who used inhalants or other drugs but not marijuana were least likely to report multidrug use. Adolescents who reported using both inhalants and marijuana were most likely to use three or more classes of drugs (73%) and to receive a diagnosis of past year alcohol (35%) and drug (39%) abuse or dependence.
  
  
  CONCLUSIONS
  Our study findings suggest that among lifetime adolescent drug users, those who use both inhalants and marijuana are at very high risk for alcohol and drug use disorders.
authors.affiliation: Center for Risk Behavior and Mental Health Research, RTI International, 3040 Cornwallis Road, Research Triangle Park, NC 27709-2194, USA. liwu@rti.org
authors.forename: Li-Tzy
authors.initials: LT
authors.lastname: Wu
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Pilowsky
authors.forename: William E
authors.initials: WE
authors.lastname: Schlenger
mesh_terms: D000280:Administration, Inhalation; D000293:Adolescent; D000437:Alcoholism / Q000453:epidemiology; D002648:Child; D003625:Data Collection; D005260:Female; D006801:Humans; D013287:Illicit Drugs; D008297:Male; D002189:Marijuana Abuse / Q000453:epidemiology*; D015995:Prevalence; D019966:Substance-Related Disorders / Q000453:epidemiology
chemical_list: D013287:Illicit Drugs