title: Left thoracoscopic thymectomy in children.
abstract: BACKGROUND
  In the management of autoimmune myasthenia, thymectomy is recognized as effective surgical therapy. The necessity of complete radical thymectomy to achieve maximal improvement has been emphasized. Video-assisted thoracoscopic surgery has been successfully used for thymectomy in adults, and more recently in children, and has been described as achieving the same radicality and functional improvement as median sternotomy or as transcervical thymectomy. The aim of this work is to report our first thoracoscopic experience in this indication.
  
  
  METHODS
  Patients with myasthenia gravis on anticholinesterase drugs and/or steroids are discussed for surgery in case of clinical deterioration despite increasing doses of medication or in case of no improvement. We decided to perform thoracoscopic thymectomies by a left-sided approach. Preoperative localization of thymic tissue is done by a thoracic CT exam. Patients are placed on their right side with a thoracic tilt under the thorax. Four thoracoscopic ports are used, a 10-mm for the camera and three 5-mm operating ports. The left lung was collapsed by selective intubation (double-lumen endotrachial intubation).
  
  
  RESULTS
  Two boys, 7.5 and 14 years old, were addressed by the department of neurology for radical thymectomy. They presented an ocular myasthenia gravis for 2 years and a mild general myasthenia gravis for 7 years. The operative times were 120 and 240 min. There was no intraoperative or postoperative complication. Duration of thoracic drainage was 2 days. The children were discharged on the third postoperative day. For the second procedure, an ultrasound exam during surgery was necessary to localize the thymus exactly, thus enabling its complete resection without the need for a conversion. The follow-up is 19 and 7 months with a clinical improvement enabling the diminution of medication for both children, the end of ptosis for the first child, and the general improvement of muscle strength for the second.
  
  
  CONCLUSIONS
  Thoracoscopic thymectomy in children with juvenile myasthenia gravis seems to offer a complete surgical resection, as do open techniques. In case of difficulties in finding the thymus, an ultrasound exam is feasible to enable complete resection. The left-sided thoracoscopic approach gives a good mediastinal and cervical exposition. Furthermore, being less painful in the postoperative period, it presents a less pronounced impairment of pulmonary function, and it presents good cosmetic effect.
authors.affiliation: Department of Pediatric Surgery, Hospital Robert Debré, 48 bd Sérurier, 75019, Paris, France.
authors.forename: E
authors.initials: E
authors.lastname: Seguier-Lipszyc
authors.forename: A
authors.initials: A
authors.lastname: Bonnard
authors.forename: P
authors.initials: P
authors.lastname: Evrard
authors.forename: C
authors.initials: C
authors.lastname: Garel
authors.forename: A
authors.initials: A
authors.lastname: De Ribier
authors.forename: Y
authors.initials: Y
authors.lastname: Aigrain
authors.forename: P
authors.initials: P
authors.lastname: de Lagausie
mesh_terms: D000293:Adolescent; D002648:Child; D006801:Humans; D008297:Male; D009157:Myasthenia Gravis / Q000601:surgery*; D013906:Thoracoscopy / Q000379:methods*; D013934:Thymectomy / Q000379:methods*