title: [Molecular mechanisms of bone calcification].
abstract: Bone matrix consists mainly of hydroxyapatite and organics. The latter include various substances which interact with minerals. Osteoblasts secrete these organic substances and control crystal formation and growth of hydroxyapatite. The authors discuss the molecular mechanisms of calcification by focusing on the mineral/organic interaction.
authors.affiliation: Department of MENICON Cartilage & Bone Regeneration, Graduate School of Medicine, The University of Tokyo.
authors.forename: Kazuto
authors.initials: K
authors.lastname: Hoshi
authors.forename: Hidehiro
authors.initials: H
authors.lastname: Ozawa