title: [Analysis on the characteristics of blood serum Ab-IgG detective result of severe acute respiratory syndrome patients in Guangzhou, China].
abstract: OBJECTIVE
  To probe blood serum Ab-IgG characteristics of severe acute respiratory syndrome (SARS) patients in Guangzhou and investigate the related factors.
  
  
  METHODS
  The serum of such population diagnosed as SARS convalescent patients, non-SARS patients, family consanguineous contraction persons, wild animal and vegetable salesman and community common people was collected. The lab detective method of ELISA was adopted for these serum samples. And the epidemic investigations for the SARS patients were also carried out.
  
  
  RESULTS
  Of these populations, the detective rate of Ab-IgG for the clinic diagnosed SARS patients, which was 53.7%; That for the wild animal salesman and community common people were 16.7% and 0.9%, respectively. Among the clinic diagnosed SARS patients, the positive antibody detective rate was 90.4% for those which had specific contact history or infectivity, which was higher than that for other population. Among the specific contact history or infectivity cases, the antibody positive rate for the young and the old was lower than that for the adult. Meanwhile the difference did not exist among other cases. The antibody positive rate was identical between the male and the female. And the antibody detective rate was decreased by the month.
  
  
  CONCLUSIONS
  As a whole SARS-CoV Ab-IgG detective rate for the clinic diagnosed SARS patients was 53.7% only. The reasons for that mainly lie in the wrong clinic diagnosis besides these factors such as age, hormone use and reagent and so on. The combination of lab detection results and epidemic investigation was propitious to the diagnosis veracity. It was impossible for the sub-clinic infection of SARS-CoV virus. The importance in the virus transmitting course need to be further studied.
authors.affiliation: Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Du
authors.forename: Ji-chun
authors.initials: JC
authors.lastname: Qiu
authors.forename: Ming
authors.initials: M
authors.lastname: Wang
authors.forename: Duan-hua
authors.initials: DH
authors.lastname: Zhou
authors.forename: Xiao-ning
authors.initials: XN
authors.lastname: Liu
authors.forename: Yang
authors.initials: Y
authors.lastname: Gao
authors.forename: Yu-fei
authors.initials: YF
authors.lastname: Liu
authors.forename: Biao
authors.initials: B
authors.lastname: DI
authors.forename: Li-juan
authors.initials: LJ
authors.lastname: He
authors.forename: Peng-zhe
authors.initials: PZ
authors.lastname: Tai
authors.forename: Wei-si
authors.initials: WS
authors.lastname: Liu
authors.forename: Xiu-zhen
authors.initials: XZ
authors.lastname: Zhou
authors.forename: Bing-ying
authors.initials: BY
authors.lastname: Pan
authors.forename: Xiao-zhong
authors.initials: XZ
authors.lastname: Zou
authors.forename: Hui-fang
authors.initials: HF
authors.lastname: Xu
authors.forename: Rong-sen
authors.initials: RS
authors.lastname: Mo
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D045473:Severe acute respiratory syndrome-related coronavirus / Q000276:immunology*; D016036:Seroepidemiologic Studies; D045169:Severe Acute Respiratory Syndrome / Q000453:epidemiology* / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G