title: Validating schizotaxia and its place in studies of preventing schizophrenia by psychopharmacological intervention.
abstract: Schizotaxia is a stable syndrome of neuropsychological deficits and negative symptoms found in relatives of schizophrenic patients. These may represent special vulnerability to schizophrenia. Five areas of deficit are enumerated and suggestions as to the potential value of pre-illness interventions are discussed.
authors.affiliation: Department of Psychiatry, University of California, San Diego, USA.
authors.forename: Ming T
authors.initials: MT
authors.lastname: Tsuang
authors.forename: William S
authors.initials: WS
authors.lastname: Stone
authors.forename: Sarah I
authors.initials: SI
authors.lastname: Tarbox
authors.forename: Stephen V
authors.initials: SV
authors.lastname: Faraone
mesh_terms: D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D004198:Disease Susceptibility; D005190:Family; D006801:Humans; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000145:classification / Q000235:genetics / Q000517:prevention & control*; D012565:Schizophrenic Psychology; D012569:Schizotypal Personality Disorder / Q000235:genetics / Q000517:prevention & control
chemical_list: D014150:Antipsychotic Agents