Sensitivity of fungi isolated from onychomycosis to Eugenia cariophyllata essential oil and eugenol.
The antifungal activity of Eugenia cariophyllata essential oil and eugenol, its major constituent, on fungal strains isolated from onychomycosis was evaluated. The natural products presented prominent antifungal action with MIC of 1% and 4%, respectively.
Gayoso
C W
CW
Department of Health Promotion, Health Science Center, Federal University of Paraíba, João Pessoa, Brazil.
Lima
E O
EO
Oliveira
V T
VT
Pereira
F O
FO
Souza
E L
EL
Lima
I O
IO
Navarro
D F
DF
D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D005054:Eugenol / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects*; D014009:Onychomycosis / Q000382:microbiology; D008517:Phytotherapy; D010938:Plant Oils / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D027842:Syzygium
D000935:Antifungal Agents; D010938:Plant Oils; D005054:Eugenol