Role of exercise in rehabilitation of cancer survivors.
Approximately 70% of all children diagnosed with malignancy become long-term survivors. Anthracycline cardiotoxicity may complicate physical performance and invite a "spectrum of disuse." There is a paucity of information derived from longitudinal, prospective, randomized clinical trials of exercise in cancer survivors, and there are no guidelines concerning the risk of recreational (non-competetive) exercise in adolescent and young adult patients with anthracycline cardiomyopathy. This review will discuss screening procedures that should be performed when assigning exercise regimens to cancer survivors with or without evidence of left ventricular dysfunction. Current recommendations for exercise testing and exercise prescription are also provided.
Braith
Randy W
RW
Center for Exercise Science, College of Health and Human Performance and the College of Medicine, University of Florida, Gainesville, Florida 32611, USA. rbraith@hhp.ufl.edu
D018943:Anthracyclines / Q000009:adverse effects; D009202:Cardiomyopathies / Q000139:chemically induced / Q000534:rehabilitation; D002986:Clinical Trials as Topic; D005081:Exercise Therapy; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000534:rehabilitation*; D017741:Survivors
D018943:Anthracyclines