[Synthesis of mixed complexes of lanthanum with 2,2-bipyridyl and 1,10-phenanthroline and study of the interaction of the complexes with DNA].
A mixed complex of La with 2,2-bipyridyl (dpy) and 1,10-phenanthroline(phen) was synthesized. Elemental analysis, IR and TGA of the complex were investigated, thus it was proved that the conformation of it was La(dpy)(phen)Cl3. The interaction of the complex with DNA has been studied also. The spectra showed that the interaction between La(dpy)(phen)Cl3 and DNA experienced intercalation of long-range self-assembly. The study made it clear that the synthesized mixed complex La(dpy)(phen)Cl3 can interact with DNA, and La(dpy)(phen)Cl3 can be used for probing a nucleic acid.
Fang
Guang-rong
GR
Faculty of Chemistry and Material Science, Hubei University, Wuhan, China.
Li
Ling
L
Cai
Zhao-xia
ZX
Liu
Li-ming
LM
Song
Gong-wu
GW
D015082:2,2'-Dipyridyl / Q000737:chemistry* / Q000494:pharmacology; D002942:Circular Dichroism / Q000379:methods; D004247:DNA / Q000737:chemistry*; D007811:Lanthanum / Q000737:chemistry* / Q000494:pharmacology; D009690:Nucleic Acid Conformation / Q000187:drug effects*; D010618:Phenanthrolines / Q000737:chemistry* / Q000494:pharmacology; D010777:Photochemistry
D010618:Phenanthrolines; D015082:2,2'-Dipyridyl; D007811:Lanthanum; D004247:DNA; C025205:1,10-phenanthroline