title: Late-onset idiopathic diffuse lamellar keratitis after laser in situ keratomileusis.
abstract: We report a case of late-onset diffuse lamellar keratitis (DLK) in the left eye of a 56-year-old white woman 3 years after uneventful bilateral laser in situ keratomileusis (LASIK). Slitlamp examination revealed stage 3 DLK with diffuse, multifocal, dot-like, and granular haze in the interface. The DLK did not have an obvious causative agent such as trauma or epithelial defects and responded rapidly to topical corticosteroid therapy. Surgery was performed to relift the flap, remove cellular infiltrates, and obtain cultures. The microbiology culture was negative. This case indicates that DLK can occur several years after LASIK without an obvious cause.
authors.affiliation: The Eye Institute of Utah, Salt Lake City, Utah 84107, USA. georgejin@hotmail.com
authors.forename: George J C
authors.initials: GJ
authors.lastname: Jin
authors.forename: W Andrew
authors.initials: WA
authors.lastname: Lyle
authors.forename: Kevin H
authors.initials: KH
authors.lastname: Merkley
mesh_terms: D000287:Administration, Topical; D001251:Astigmatism / Q000601:surgery*; D003320:Corneal Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D011183:Postoperative Complications; D011239:Prednisolone / Q000627:therapeutic use; D013524:Surgical Flaps
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone