[Expression of glucose transporter 1 in the blood-brain barrier around hematoma in rats with cerebral hemorrhage].
OBJECTIVE
To observe the expression of glucose transporter 1 (GLUT1) in the blood-brain barrier around the hematoma in rats with cerebral hemorrhage.


METHODS
Brain tissue around the hematoma in rats with cerebral hemorrhage was prepared for GLUT1 detection by immunohistochemistry.


RESULTS
The expression of GLUT1 upregulated within 48 h after cerebral hemorrhage and downregulated afterwards.


CONCLUSIONS
Protective reaction of the blood-brain barrier can be initiated to ensure glucose supply to the neurons against the injury by cerebral hemorrhage.
Li
Zhong-Qiu
ZQ
Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Lu
Bing-Xun
BX
Lü
Tian-Ming
TM
D000818:Animals; D001812:Blood-Brain Barrier; D002543:Cerebral Hemorrhage / Q000150:complications / Q000378:metabolism* / Q000503:physiopathology; D005260:Female; D051272:Glucose Transporter Type 1 / Q000096:biosynthesis*; D006406:Hematoma / Q000209:etiology / Q000378:metabolism* / Q000503:physiopathology; D008297:Male; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley
D051272:Glucose Transporter Type 1