title: Polioencephalomalacia in adult sheep grazing pastures with prostrate pigweed.
abstract: Polioencephalomalacia was diagnosed in 2 animals from different farms. In apparently healthy animals from same farms, fecal thiaminase and a significant reduction in erythrocyte trans-ketolase activity was observed. The presence of thiaminase in Amaranthus blitoides could have contributed to the development of polioencephalomalacia in sheep grazing on natural pastures.
authors.affiliation: Department of Animal Pathology, Veterinary Faculty, University of Zaragoza, C/Miguel Servet, 177, 50013-Zaragoza, Spain. jjramos@unizar.es
authors.forename: Juan José
authors.initials: JJ
authors.lastname: Ramos
authors.forename: Luis Miguel
authors.initials: LM
authors.lastname: Ferrer
authors.forename: Laura
authors.initials: L
authors.lastname: García
authors.forename: Antonio
authors.initials: A
authors.lastname: Fernández
authors.forename: Araceli
authors.initials: A
authors.lastname: Loste
mesh_terms: D027721:Amaranthus / Q000201:enzymology / Q000506:poisoning*; D000821:Animal Feed; D000818:Animals; D004678:Encephalomalacia / Q000175:diagnosis / Q000201:enzymology / Q000662:veterinary*; D017809:Fatal Outcome; D005243:Feces / Q000737:chemistry / Q000201:enzymology; D005506:Food Contamination; D006867:Hydrolases / Q000378:metabolism; D010939:Plant Poisoning / Q000201:enzymology / Q000209:etiology / Q000662:veterinary*; D006109:Poaceae; D012756:Sheep; D012757:Sheep Diseases / Q000175:diagnosis* / Q000201:enzymology / Q000209:etiology; D013030:Spain; D013832:Thiamine Deficiency / Q000150:complications / Q000209:etiology / Q000662:veterinary; D014174:Transketolase / Q000378:metabolism
chemical_list: D014174:Transketolase; D006867:Hydrolases; C022731:thiaminase II