title: [Expression of cyclooxygenase-2 in the testes and epididymides of adult male rats].
abstract: OBJECTIVE
  To investigate the expression of cyclooxygenase-2 (cox-2) in the testes and epididymides of adult male rats and its significance.
  
  
  METHODS
  Immunohistochemical staining was used to detect the expression and localization of cox-2 in the testicle and epididymal tissues of 40 adult male SD rats.
  
  
  RESULTS
  Strong cox-2 immunoreactivity was detected in the epididymides and testes of the rats. In the caput epididymides, cox-2 expressed mainly in the epithelial nuclei and partly in the cytoplasm. Cox-2 was also found positive in the testis nuclei and cytoplasm.
  
  
  CONCLUSIONS
  Immunohistochemical staining is a fairly sensitive method for detecting cox-2 expression in the testes and epididymides of adult male rats.
authors.affiliation: Center of Reproductive Medicine, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
authors.forename: Xiao-Ni
authors.initials: XN
authors.lastname: Hou
authors.forename: Han-Wang
authors.initials: HW
authors.lastname: Zhang
authors.forename: Yu-Feng
authors.initials: YF
authors.lastname: Li
mesh_terms: D000818:Animals; D051546:Cyclooxygenase 2 / Q000096:biosynthesis*; D004822:Epididymis / Q000201:enzymology*; D007150:Immunohistochemistry; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012680:Sensitivity and Specificity; D013737:Testis / Q000201:enzymology*
chemical_list: D051546:Cyclooxygenase 2