[Expression of cyclooxygenase-2 in the testes and epididymides of adult male rats].
OBJECTIVE
To investigate the expression of cyclooxygenase-2 (cox-2) in the testes and epididymides of adult male rats and its significance.


METHODS
Immunohistochemical staining was used to detect the expression and localization of cox-2 in the testicle and epididymal tissues of 40 adult male SD rats.


RESULTS
Strong cox-2 immunoreactivity was detected in the epididymides and testes of the rats. In the caput epididymides, cox-2 expressed mainly in the epithelial nuclei and partly in the cytoplasm. Cox-2 was also found positive in the testis nuclei and cytoplasm.


CONCLUSIONS
Immunohistochemical staining is a fairly sensitive method for detecting cox-2 expression in the testes and epididymides of adult male rats.
Hou
Xiao-Ni
XN
Center of Reproductive Medicine, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Zhang
Han-Wang
HW
Li
Yu-Feng
YF
D000818:Animals; D051546:Cyclooxygenase 2 / Q000096:biosynthesis*; D004822:Epididymis / Q000201:enzymology*; D007150:Immunohistochemistry; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012680:Sensitivity and Specificity; D013737:Testis / Q000201:enzymology*
D051546:Cyclooxygenase 2