title: [Hormone replacement therapy and vascular function].
abstract: Hormone replacement therapy (HRT) by estrogen has a cardioprotective effect in postmenopausal women. This effect results partly from the direct actions of estrogen on vascular receptors. These are mainly endothelium-dependent or endothelium-independent vascular relaxing effects. Increases in prostacyclin and bradykinin, and a decrease in endothelin-1 by estrogen are involved.
authors.affiliation: Second Department of Internal Medicine, Gunma University School of Medicine.
authors.forename: H
authors.initials: H
authors.lastname: Sumino
authors.forename: M
authors.initials: M
authors.lastname: Kurabayashi
authors.forename: S
authors.initials: S
authors.lastname: Ichikawa