[Vitamin-K].
Number of adynamic bone disease (ABD) is increasing in dialysis patients, and it is necessary to find the effective treatment for ABD. Vitamin-K (V-K) is an essential cofactor for the site-specific carboxylation of osteocalcin. Furthermore, it increases the bone formation and decreases the bone resorption. On the other hand, V-K status is poor in dialysis patients caused by dietary restriction. V-K supplementation is paid attention as the treatment for ABD.
Yamamoto
H
H
Division of Nephrology and Hypertension, Jikei University School of Medicine.