Calcium and phosphorus metabolism in patients who have chronic kidney disease.
Disturbances in calcium and phosphorus metabolism are almost invariable consequences of chronic kidney disease (CKD). Because the capacity to regulate calcium and phosphorus metabolism becomes compromised progressively as kidney function declines, calcium and phosphorus homeostasis is disrupted and serum calcium or phosphorus levels are perturbed in many patients with CKD. The level of interest in, and concerns about, abnormalities in calcium and phosphorus metabolism among patients with CKD has increased substantially in recent years. Strategies for clinical management are being revised, and recent recommendations differ substantially from those used previously with a renewed emphasis on safety.
Goodman
William G
WG
Division of Nephrology, Department of Medicine, David Geffen School of Medicine at the University of California at Los Angeles, University of California at Los Angeles Medical Center, CA 90095, USA. wgoodman@ucla.edu
D002118:Calcium / Q000378:metabolism*; D002128:Calcium Metabolism Disorders / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000503:physiopathology*; D010758:Phosphorus / Q000378:metabolism*; D010760:Phosphorus Metabolism Disorders / Q000209:etiology / Q000503:physiopathology*
D010758:Phosphorus; D002118:Calcium