Microwave-assisted synthesis of isonitriles: a general simple methodology.
[reaction: see text] A facile conversion of formamides to isonitriles under very mild conditions and microwave irradiation is described. This simple and efficient method has been applied for the synthesis of both aliphatic and aromatic isonitriles in high yields.
Porcheddu
Andrea
A
Dipartimento di Chimica, Università degli Studi di Sassari, via Vienna 2, 07100 Sassari. anpo@uniss.it
Giacomelli
Giampaolo
G
Salaris
Margherita
M
D008872:Microwaves; D015394:Molecular Structure; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry / Q000528:radiation effects; D010084:Oxidation-Reduction
D009570:Nitriles