title: Combinatorial libraries - from solution to 2D microarrays.
abstract: Enzymatic modifications of split and mix libraries were followed by "pulling down" onto a 2-dimensional DNA microarray, via PNA tagging; this allowed complete library interrogation of all members of the split and mix library.
authors.affiliation: School of Chemistry, University of Southampton, Southampton, UK SO17 1BJ.
authors.forename: Juan José
authors.initials: JJ
authors.lastname: Díaz-Mochón
authors.forename: Laurent
authors.initials: L
authors.lastname: Bialy
authors.forename: Lise
authors.initials: L
authors.lastname: Keinicke
authors.forename: Mark
authors.initials: M
authors.lastname: Bradley
mesh_terms: D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D015394:Molecular Structure; D020411:Oligonucleotide Array Sequence Analysis; D010447:Peptide Hydrolases / Q000737:chemistry; D020135:Peptide Nucleic Acids; D016315:Proto-Oncogene Proteins c-abl / Q000737:chemistry; D012996:Solutions / Q000737:chemistry
chemical_list: D020135:Peptide Nucleic Acids; D012996:Solutions; D016315:Proto-Oncogene Proteins c-abl; D010447:Peptide Hydrolases