[Modulation of intracellular Ca2+ by estrogen].
Regulatory pathways of intracellular Ca(2+) by estrogen can be classified into two, both of which function in the plasma membrane. One is the rapid rise of intracellular Ca(2+) caused by the physiologic dose of estrogen via estrogen receptor from both extracellular and intracellular sources. The other is the inhibition of the agonist-induced increase in intracellular Ca(2+) by the supraphysiologic dose of estrogen, and this action is not likely to be mediated by estrogen receptor.
Akishita
M
M
Department of Geriatric Medicine, Kyorin University School of Medicine.