title: Lysine-enediyne conjugates as photochemically triggered DNA double-strand cleavage agents.
abstract: Statistical analysis of DNA-photocleavage by two types of lysine-enediyne conjugates confirms that more double-strand breaks are produced than can be accounted for by coincident single-strand breaks.
authors.affiliation: Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306-4390, USA.
authors.forename: Serguei V
authors.initials: SV
authors.lastname: Kovalenko
authors.forename: Igor V
authors.initials: IV
authors.lastname: Alabugin
mesh_terms: D004247:DNA / Q000737:chemistry* / Q000528:radiation effects*; D053903:DNA Breaks, Double-Stranded; D053281:Enediynes / Q000737:chemistry*; D008239:Lysine / Q000737:chemistry*; D015394:Molecular Structure; D010777:Photochemistry; D010957:Plasmids / Q000737:chemistry
chemical_list: D053281:Enediynes; D004247:DNA; D008239:Lysine