title: Liver failure and transplantation after itraconazole treatment for toenail onychomycosis.
abstract: Three weeks after completing a 4-pulse course of itraconazole for toenail onychomycosis, a 25-year-old woman patient developed severe liver crisis and required an emergency liver transplant. We report the case and discuss the use of itraconazole in onychomycosis and dermatomycoses.
authors.affiliation: Department of Dermatology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, 64239 Israel. asrebrnik@hotmail.co.il
authors.forename: A
authors.initials: A
authors.lastname: Srebrnik
authors.forename: S
authors.initials: S
authors.lastname: Levtov
authors.forename: R
authors.initials: R
authors.lastname: Ben-Ami
authors.forename: S
authors.initials: S
authors.lastname: Brenner
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D005533:Foot Dermatoses / Q000188:drug therapy; D006801:Humans; D017964:Itraconazole / Q000009:adverse effects* / Q000627:therapeutic use; D017093:Liver Failure / Q000139:chemically induced* / Q000601:surgery; D008111:Liver Function Tests; D016031:Liver Transplantation; D014009:Onychomycosis / Q000188:drug therapy*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole