Antiviral reactivities of gammadelta T cells.
The complex antiviral immune mechanisms involve both adaptive and innate reactions mediated by gammadelta T lymphocytes, whose unique immunosurveillance contributions are analyzed here in different clinical and experimental settings. It is beyond any doubt that the fast, potent, cytotoxic as well as non-cytolytic antiviral activities of gammadelta T cells are critical in protecting the host against diverse viral pathogens.
Poccia
Fabrizio
F
Unit of Cellular Immunology, National Institute for Infectious Diseases Lazzaro Spallanzani - IRCCS, Via Portuense 292, 00149 Rome, Italy. poccia@inmi.it
Agrati
Chiara
C
Martini
Federico
F
Capobianchi
Maria Rosaria
MR
Wallace
Marianne
M
Malkovsky
Miroslav
M
D000818:Animals; D004266:DNA Virus Infections / Q000276:immunology; D018178:Flaviviridae Infections / Q000276:immunology; D006801:Humans; D009976:Orthomyxoviridae Infections / Q000276:immunology; D012327:RNA Virus Infections / Q000276:immunology; D012192:Retroviridae Infections / Q000276:immunology; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D014777:Virus Diseases / Q000276:immunology*