title: [FTIR study on normal and cancerous lung tissues].
abstract: Tissues of cancerous and normal lungs were analysed directly and fast by Fourier transform infrared spectroscopy with OMNI-sampler. The result indicated that some remarkable spectral differences were among normal and cancerous lung tissues in frequency, intensity and shape of the absorption peaks. These facts indicated significant differences of content, structure and conformation of proteins, nucleic acids and lipids in different types of lung tissues. The present results suggested that Fourier transform infrared spectrometry (FTIR) could show the properties of normal and cancerous lung tissues at the molecular level. It was able to provide rich and reliable information for investigation of normal and cancerous lung tissues and could be used as a convenient and reliable diagnostic tool for some tumors.
authors.affiliation: College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, China.
authors.forename: Cun-gui
authors.initials: CG
authors.lastname: Cheng
authors.forename: Hong-qi
authors.initials: HQ
authors.lastname: Shi
authors.forename: Xiao-jun
authors.initials: XJ
authors.lastname: Zhu
authors.forename: Rong-quan
authors.initials: RQ
authors.lastname: Zheng
authors.forename: Shou-tian
authors.initials: ST
authors.lastname: Zhu
mesh_terms: D002283:Carcinoma, Bronchogenic / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D008055:Lipids / Q000737:chemistry*; D008168:Lung / Q000737:chemistry*; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology; D009363:Neoplasm Proteins / Q000737:chemistry; D009696:Nucleic Acids / Q000737:chemistry; D012016:Reference Values; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods
chemical_list: D008055:Lipids; D009363:Neoplasm Proteins; D009696:Nucleic Acids