Antibacterial and antifungal activity of pinosylvin, a constituent of pine.
The antibacterial and antifungal activities of pinosylvin (3,5-dihydroxy-trans-stilbene), a constituent of pine, were studied and compared with those of resveratrol (3,5,4'-trihydroxy-trans-stilbene). Pinosylvin exhibited more potent growth inhibitory activity against Candida albicans and Saccharomyces cerevisiae.
Lee
S K
SK
College of Pharmacy, Ewha Womans University, Seoul 120-750, South Korea. sklee@ewha.ac.kr
Lee
H J
HJ
Min
H Y
HY
Park
E J
EJ
Lee
K M
KM
Ahn
Y H
YH
Cho
Y J
YJ
Pyee
J H
JH
D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D002176:Candida albicans / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D006801:Humans; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D028223:Pinus; D018515:Plant Leaves; D010938:Plant Oils / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D012440:Saccharomyces / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D013267:Stilbenes / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000094162:Phytoalexins
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D010938:Plant Oils; D013267:Stilbenes; C049032:pinosylvin; D000094162:Phytoalexins