[Ehrlich tumor cells stimulate T-cell production of interferon-gamma and are resistant to autocrine nitric oxide].
Ehrlich tumor cells released factors which activated T-cell production of interferon-gamma and triggered a mechanism of nitric oxide (NO) production instead of interferon-gamma. When cultured in vitro, they produced NO without stimulation and responded to interferon-gamma by an output rate of NO significantly greater than that in bone marrow cells. Unlike P-815 cells, those of Ehrlich tumor proved resistant to autocrine NO.
Bel'skiĭ
Iu P
IuP
Bel'skaia
N V
NV
Danilets
M G
MG
Trofimova
E S
ES
Patrushev
V K
VK
Agafonov
V I
VI
D000818:Animals; D019898:Autocrine Communication; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism*; D005260:Female; D007371:Interferon-gamma / Q000096:biosynthesis*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D009569:Nitric Oxide / Q000378:metabolism*; D013601:T-Lymphocytes / Q000378:metabolism*
D009569:Nitric Oxide; D007371:Interferon-gamma