NK cell recognition.
The integrated processing of signals transduced by activating and inhibitory cell surface receptors regulates NK cell effector functions. Here, I review the structure, function, and ligand specificity of the receptors responsible for NK cell recognition.
Lanier
Lewis L
LL
Department of Microbiology and Immunology and the Cancer Research Institute, University of California, San Francisco School of Medicine, San Francisco, California 94143-0414, USA. lanier@itsa.ucsf.edu
D000818:Animals; D015395:Histocompatibility Antigens Class I / Q000378:metabolism; D006801:Humans; D007113:Immunity, Innate; D007694:Killer Cells, Natural / Q000276:immunology*; D008024:Ligands; D051379:Mice; D018448:Models, Immunological; D011971:Receptors, Immunologic / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction
D015395:Histocompatibility Antigens Class I; D008024:Ligands; D011971:Receptors, Immunologic