Refractory status epilepticus.
OBJECTIVE
Although conventional anticonvulsant agents can terminate status epilepticus in most cases, a substantial minority of patients develops medically refractory status and requires more aggressive care. This review explores the options available.


RESULTS
Increasing numbers of previously unexpected etiologies for refractory status epilepticus continue to be reported. There are also some promising new therapies on the horizon, both for the short and the longer terms.


CONCLUSIONS
Refractory status epilepticus, while a challenge to the intensivist, can be treated with drugs that are commonly used by intensivists. The cooperation of an interested electroencephalographer is vital.
Bleck
Thomas P
TP
The University of Virginia, Charlottesville, Virginia 22908-0394, USA. tblcek@virginia.edu
D000777:Anesthetics / Q000627:therapeutic use*; D000927:Anticonvulsants / Q000627:therapeutic use*; D004351:Drug Resistance; D004569:Electroencephalography; D006801:Humans; D013226:Status Epilepticus / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology*
D000777:Anesthetics; D000927:Anticonvulsants