title: Spotted fever group and typhus group rickettsioses in humans, South Korea.
abstract: The presence of the nucleic acid of the spotted fever group (SPG) and typhus group (TG) rickettsiae was investigated in 200 serum specimens seropositive for SFG rickettsiae by multiplex-nested polymerase chain reaction with primers derived from the rickettsial outer membrane protein B gene. The DNA of SFG, TG, or both rickettsiae was amplified in the 24 serum specimens, and sequence analysis showed Rickettsia conorii, R. japonica, and R. felis in the specimens. R. conorii and R. typhi were found in 7 serum specimens, which indicated the possibility of dual infection in these patients. These findings suggest that several kinds of rickettsial diseases, including boutonneuse fever, rickettsialpox, R. felis infection, and Japanese spotted fever, as well as scrub typhus and murine typhus, are occurring in Korea.
authors.affiliation: Konkuk University, Choongbuk, Republic of Korea.
authors.forename: Yeon-Joo
authors.initials: YJ
authors.lastname: Choi
authors.affiliation: Konkuk University, Choongbuk, Republic of Korea.
authors.forename: Won-Jong
authors.initials: WJ
authors.lastname: Jang
authors.affiliation: Konkuk University, Choongbuk, Republic of Korea.
authors.forename: Jong-Hyun
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Konkuk University, Choongbuk, Republic of Korea.
authors.forename: Ji-Sun
authors.initials: JS
authors.lastname: Ryu
authors.affiliation: Konkuk University, Choongbuk, Republic of Korea.
authors.forename: Seung-Hyun
authors.initials: SH
authors.lastname: Lee
authors.affiliation: Konkuk University, Choongbuk, Republic of Korea.
authors.forename: Kyung-Hee
authors.initials: KH
authors.lastname: Park
authors.affiliation: Pusan National University, Pusan, Republic of Korea.
authors.forename: Hyung-Suk
authors.initials: HS
authors.lastname: Paik
authors.affiliation: Cheju National University College of Medicine, Jeju, Republic of Korea.
authors.forename: Young-Sang
authors.initials: YS
authors.lastname: Koh
authors.affiliation: Seoul National University College of Medicine and Institute of Endemic Disease, Seoul, Republic of Korea.
authors.forename: Myung-Sik
authors.initials: MS
authors.lastname: Choi
authors.affiliation: Seoul National University College of Medicine and Institute of Endemic Disease, Seoul, Republic of Korea.
authors.forename: Ik-Sang
authors.initials: IS
authors.lastname: Kim
mesh_terms: D000942:Antigens, Bacterial / Q000737:chemistry / Q000235:genetics; D001425:Bacterial Outer Membrane Proteins / Q000737:chemistry / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics; D001483:Base Sequence; D003001:Cloning, Molecular; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D006801:Humans; D007723:Korea / Q000453:epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D012281:Rickettsia / Q000235:genetics / Q000302:isolation & purification*; D012282:Rickettsia Infections / Q000097:blood / Q000453:epidemiology* / Q000382:microbiology; D016415:Sequence Alignment
chemical_list: D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D004269:DNA, Bacterial; C073150:rOmp B protein, Rickettsia