[Risk factors of renal failure in the early post-liver transplantation period].
OBJECTIVE
To study the risk factors of renal failure in the early post-liver transplantation period.


METHODS
92 consecutive liver transplantation cases were reviewed and a multi-factor analysis of presumed risk factors of early post-transplantation period renal failure was conducted. The factors analyzed were total bilirubin level, prothrombin activity, onset of structural renal disease, onset of gastrointestinal hemorrhage, whether the patient underwent large-volume paracentesis, or underwent plasmapheresis therapy, needed renal replacement therapy, the operation method used, the bleeding volume during operation and the immunosuppressive agents used.


RESULTS
Of the 92 patients, 29 (31.5%) developed acute renal failure (ARF) in the early postoperative period. Multi-factor analysis revealed a high pre-transplantation serum creatinine level and low prothrombin activity as risk factors for development of ARF.


CONCLUSIONS
ARF is a frequent medical complication after liver transplantation. A high pre-transplantation serum creatinine level and low prothrombin activity are risk factors of its development.
Zhu
Feng-xue
FX
Department of Hepatobiliary Surgery, People's Hospital of Beijing University, Beijing 100044, China. gandanwk@vip.sina.com
Liu
Chun-jun
CJ
Zhu
Ji-ye
JY
Li
Guang-ming
GM
Huang
Lei
L
Wang
Dong
D
Gao
Jie
J
Zheng
Zhi-min
ZM
Leng
Xi-sheng
XS
D058186:Acute Kidney Injury / Q000453:epidemiology* / Q000209:etiology; D000293:Adolescent; D000328:Adult; D002681:China / Q000453:epidemiology; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000601:surgery; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011516:Prothrombin / Q000378:metabolism; D012307:Risk Factors
D011516:Prothrombin; D003404:Creatinine