title: The hydrogen-bonding network in (+)-N-tosyl-L-glutamic acid.
abstract: The asymmetric unit of the alpha polymorph of (+)-N-tosyl-L-glutamic acid, C12H15NO6S, contains two independent molecules which differ in conformation. The carboxylic acid groups form an infinite zigzag chain with characteristic R(2)(2)(8) rings running along the b axis. Intermolecular N-H...O and C-H...O contacts mediate the formation of a three-dimensional supramolecular structure described by R(4)(3)(22), R(6)(6)(44) and R(8)(8)(54) graph-set descriptors. Comparison of the extended structure with that of N-(benzenesulfonyl)glutamic acid shows that a subtle difference in the periphery of the molecule, i.e. the replacement of the toluyl group with a phenyl group, can be accompanied by dramatic changes in molecular assembly.
authors.affiliation: Warsaw University of Technology, Faculty of Chemistry, Noakowskiego 3, 00-664 Warszawa, Poland. janzac@ch.pw.edu.pl
authors.forename: Janusz
authors.initials: J
authors.lastname: Zachara
authors.forename: Izabela
authors.initials: I
authors.lastname: Madura
authors.forename: Halina
authors.initials: H
authors.lastname: Hajmowicz
authors.forename: Ludwik
authors.initials: L
authors.lastname: Synoradzki
mesh_terms: D018360:Crystallography, X-Ray; D018698:Glutamic Acid / Q000031:analogs & derivatives* / Q000737:chemistry*; D006860:Hydrogen Bonding; D008968:Molecular Conformation; D014105:Tosyl Compounds / Q000737:chemistry*
chemical_list: D014105:Tosyl Compounds; D018698:Glutamic Acid