title: Mild metal-free syn-stereoselective ring opening of activated epoxides and aziridines with aryl borates.
abstract: A conceptually new, simple and practical method for the syn-nucleophilic displacement of aryl and vinyl epoxides and aryl aziridines with (substituted) phenols, using aryl borates as activating nucleophiles under neutral conditions, is reported.
authors.affiliation: Dipartimento di Chimica Bioorganica e Biofarmacia, Università di Pisa, Via Bonanno 33, 56126, Pisa, Italy. pineschi@farm.unipi.it
authors.forename: Mauro
authors.initials: M
authors.lastname: Pineschi
authors.forename: Ferruccio
authors.initials: F
authors.lastname: Bertolini
authors.forename: Robert M
authors.initials: RM
authors.lastname: Haak
authors.forename: Paolo
authors.initials: P
authors.lastname: Crotti
authors.forename: Franco
authors.initials: F
authors.lastname: Macchia
mesh_terms: D001388:Aziridines / Q000737:chemistry*; D001881:Borates / Q000737:chemistry*; D004852:Epoxy Compounds / Q000737:chemistry*; D015394:Molecular Structure; D009930:Organic Chemicals / Q000737:chemistry; D013237:Stereoisomerism; D014753:Vinyl Compounds / Q000737:chemistry
chemical_list: D001388:Aziridines; D001881:Borates; D004852:Epoxy Compounds; D009930:Organic Chemicals; D014753:Vinyl Compounds