title: Degenerative disc disease in childhood and adolescence.
abstract: Degenerative disk disease (DDD) is a common cause of low back pain and leg pain in children and infants. DDD is often unrecognized and under-diagnosed. This paper presents six cases of DDD in children and discusses the clinical presentation and pathophysiology of DDD.
authors.affiliation: Department of Anatomy, Section of Neurosurgery, Saint Louis University School of Medicine, USA.
authors.forename: Jason P
authors.initials: JP
authors.lastname: Young
authors.forename: Paul H
authors.initials: PH
authors.lastname: Young
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology*; D017116:Low Back Pain / Q000209:etiology* / Q000503:physiopathology; D008159:Lumbar Vertebrae / Q000098:blood supply / Q000473:pathology*; D008297:Male; D010003:Osteoarthritis / Q000503:physiopathology; D012585:Sciatica / Q000209:etiology* / Q000503:physiopathology; D013169:Spondylolysis / Q000503:physiopathology