title: The pyrrole approach toward the synthesis of fully functionalized cup-shaped molecules.
abstract: [reaction: see text] A novel method for the synthesis of new highly functionalized cyclotrimers is described. The method consists of an original synthesis of beta-dibromosubstituted pyrroles, metalation, cycloaddition, and cyclotrimerization. The sequence is highly compatible with common functional groups and allows the construction of cup-shaped molecules functionalized both at the upper and bottom rim. This feature makes the newly formed structures useful scaffolds for the development of supramolecular receptors.
authors.affiliation: Dipartimento di Chimica, Università Ca' Foscari di Venezia, Dorsoduro 2137, I-30123 Venezia, Italy. zontac@unive.it
authors.forename: Cristiano
authors.initials: C
authors.lastname: Zonta
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Fabris
authors.forename: Ottorino
authors.initials: O
authors.lastname: De Lucchi