title: [Kinins--characteristics and role in the circulatory system].
abstract: Kinins play an important role in numerous of pathophysiological processes in organism. This paper encompasses mechanisms of kinins action and their role in the circulatory system. Individual components of the kallikrein-kinin system as well as their origin, structure and biodegeneration were described. Bradykinin B1 and B2 receptors along with their functions were discussed. Enzymes taking part in biodegradation of kinins were characterised. The role of the bradykinin as an inflammatory mediator as well as links between the kallikrein-kinin and renin-angiotensin systems, together with their contribution to myocardial ischaemia, were described.
authors.forename: Bogna
authors.initials: B
authors.lastname: Gabrylewicz
authors.forename: Michał
authors.initials: M
authors.lastname: Tendera
mesh_terms: D003327:Coronary Disease / Q000378:metabolism* / Q000503:physiopathology*; D006801:Humans; D007249:Inflammation / Q000378:metabolism / Q000503:physiopathology; D007610:Kallikreins / Q000502:physiology; D007705:Kinins / Q000378:metabolism / Q000502:physiology*; D018002:Receptors, Bradykinin / Q000502:physiology
chemical_list: D007705:Kinins; D018002:Receptors, Bradykinin; D007610:Kallikreins