title: Infective endocarditis due to Moraxella lacunata: report of 4 patients and review of published cases of Moraxella endocarditis.
abstract: Moraxella is an aerobic, oxidase-positive, Gram-negative coccobacillus, which is rarely associated with serious and invasive infections. We describe 4 cases of Moraxella lacunata endocarditis and review 12 previously published cases of Moraxella endocarditis, including 1 further case with M. lacunata, 5 with M. catarrhalis, 2 with M. phenylperuvica and the remainder consisting of 1 case each of M. liquefaciens, M. osloensis, M. nonliquefaciens and 1 non-specified. Of these 16 patients, 5 had prosthetic valves, 5 suffered from an underlying heart abnormality, and the other 6 had normal hearts. Therapy consisted of a beta-lactam antimicrobial and, in several instances, an aminoglycoside as well. The mean duration of antibiotic treatment was 35+/-13 d. Four patients (25%) underwent surgery and 4 out of 16 (25%) died. Moraxella should be added to the growing list of organisms which may occasionally cause infective endocarditis, even in patients without preexisting valvular abnormality.
authors.affiliation: Shaare Zedek Medical Centre, Jerusalem.
authors.forename: Hannah
authors.initials: H
authors.lastname: Maayan
authors.forename: Ronit
authors.initials: R
authors.lastname: Cohen-Poradosu
authors.forename: Efraim
authors.initials: E
authors.lastname: Halperin
authors.forename: Bernard
authors.initials: B
authors.lastname: Rudensky
authors.forename: Yechiel
authors.initials: Y
authors.lastname: Schlesinger
authors.forename: Amos M
authors.initials: AM
authors.lastname: Yinnon
authors.forename: David
authors.initials: D
authors.lastname: Raveh
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D004697:Endocarditis, Bacterial / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009016:Moraxella / Q000302:isolation & purification* / Q000472:pathogenicity; D045828:Moraxellaceae Infections / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents