title: Med-psych drug-drug interactions update. Antiretrovirals, part III: antiretrovirals and drugs of abuse.
abstract: The third in a series reviewing the HIV/AIDS antiretroviral drugs, this report summarizes the interactions between antiretrovirals and common drugs of abuse. In an overview format for primary care physicians and psychiatrists, the metabolism and drug interactions in the context of antiretroviral therapy are presented for the following drugs of abuse: alcohol, benzodiazepines, cocaine, GHB (liquid X), ketamine (special K), LSD (acid), MDMA (Ecstasy), opiates, PCP (angel dust), and THC (marijuana).
authors.affiliation: Uniformed Services University of the Health Sciences, F Edward Hebert School of Medicine, Bethesda, MD, USA.
authors.forename: Gary H
authors.initials: GH
authors.lastname: Wynn
authors.forename: Kelly L
authors.initials: KL
authors.lastname: Cozza
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Zapor
authors.forename: Glenn W
authors.initials: GW
authors.lastname: Wortmann
authors.forename: Scott C
authors.initials: SC
authors.lastname: Armstrong
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D044966:Anti-Retroviral Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004347:Drug Interactions; D004790:Enzyme Induction / Q000187:drug effects; D015658:HIV Infections / Q000188:drug therapy* / Q000201:enzymology; D006801:Humans; D013287:Illicit Drugs / Q000009:adverse effects* / Q000493:pharmacokinetics; D010349:Patient Compliance; D010353:Patient Education as Topic
chemical_list: D044966:Anti-Retroviral Agents; D013287:Illicit Drugs; D003577:Cytochrome P-450 Enzyme System