[Changes in the fat-acid spectrum of high-density lipoproteins as observed in men and women with acute appendicitis].
Differences in the reaction of the fat-acid spectrum of high-density lipoproteins (HDLP and HDLP3) and ethers of transfer-protein cholesterol (ETPC) as well as in the activity of lecithin cholesterin acetyltransferase and the content of cholesterol were compared for male and female patients (of the second mature age) with appendicitis. It was concluded that the female patients with appendicitis had, versus healthy women of the same age, a lower share of poly-unsaturated fat acids (PUFA) in the HDLP content and, possibly, a compensatorily intensified activity of the delta9-desaturase system; the changes were concomitant with a reduced functional HDLP activity. Within the discussed age span, the female patients with appendicitis had, versus the male patients, a more drastically reduced content of PUFA in HDLP, which was accompanied by a more intense modification of their functional activity with an active metabolism of PUFA (possibly of the omega9-row) due to ETPC.
Osochuk
S S
SS
Konevalova
N Iu
NIu
D000328:Adult; D000367:Age Factors; D001064:Appendicitis / Q000097:blood*; D005231:Fatty Acids, Unsaturated / Q000097:blood*; D005260:Female; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors
D005231:Fatty Acids, Unsaturated; D008075:Lipoproteins, HDL