[Primary hyperparathyroidism with severe skeletal involvement in one patient with parathyroid carcinoma].
Parathyroid carcinoma is an uncommon cause of primary hyperparathyroidism; however, when this condition is severe, cancer must be suspected. We report on a 28-year-old male with severe hypercalcemia, cachexia, acute pancreatitis, urolithiasis, anemia and a severe skeletal involvement with multiple fractures. The patient had a 4-cm parathyroid tumor, that was surgically excised, along with the ipsilateral thyroid lobe. During the postoperative period, he had a severe and prolonged hungry bone syndrome, with a slow recovery of fractures, with functional and anatomical sequelae in the extremities. PTH levels were adequate for the serum calcium during the 16 months of follow-up.
Ríos S
Lorena
L
Unidad de Endocrinología, Departamento de Medicina Interna, Facultad de Medicina, Universidad de la Frontera. lprios@yahoo.com
Sapunar Z
Jorge
J
Roa E
Iván
I
D000328:Adult; D005264:Femoral Fractures / Q000209:etiology* / Q000628:therapy; D005500:Follow-Up Studies; D006801:Humans; D006810:Humeral Fractures / Q000209:etiology* / Q000628:therapy; D006934:Hypercalcemia / Q000209:etiology; D006961:Hyperparathyroidism / Q000209:etiology* / Q000601:surgery; D008297:Male; D010282:Parathyroid Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery