[EHDP + vitamin D3 or vitamin K2].
We investigated the efficacy of concurrent use of two of 1alphaOH vitamin D(3), vitamin K(2), and EHDP in increasing lumbar BMD and in preventing new fracture in patients with primary osteoporosis. D(3) + K(2) showed little effect and was considered to be poor combination. EHDP + D(3) or EHDP + K(2) was superior to single use of these agents in both end points.
Kobayashi
Seneki
S
Department of Orthopaedic Surgery, Shinshu University School of Medicine.
Takaoka
Kunio
K
Shiraki
Masataka
M