title: Urodynamic alterations in patients with HTLV-1 infection.
abstract: OBJECTIVE
  The HTLV-1 is a retrovirus that causes several diseases, including tropical spastic paraparesis or HTLV-1 associated myelopathy (or TSP/HAM, as designated by the World Health Organization - WHO) described in 1985. In Brazil, the first cases were reported in 1989. In order to evaluate the urodynamic alterations of infected patients, 48 cases were studied: 26 TSP/HAM and 22 non-TSP/HAM.
  
  
  METHODS
  Evaluation was performed by testing, cystometry, abdominal pressure, differential pressure, detrusor leak point pressure, maximum flow pressure, and electromyography.
  
  
  RESULTS
  80.76% TSP/HAM patients showed hyperreflexic bladder, and 34.16% had detrusor-sphincter dyssinergia; 82.6% of this group had abnormal uroflow tests. Non-TSP/HAM patients had hyperreflexic bladders in 22.72% of the cases, and detrusor-sphincter dyssinergia was not assessed. For these patients, uroflow rate was normal in 70% of the cases.
  
  
  CONCLUSIONS
  Patients infected by the HTLV-1, with or without myelopathy, present significant urodynamic abnormalities and must have a complete urologic and urodynamic evaluation.
authors.affiliation: Section of Urology, Porto Alegre General Hospital, Federal University of Rio Grande do Sul, Brazil.
authors.forename: Cláudio L M
authors.initials: CL
authors.lastname: Lima
authors.forename: Giorgio
authors.initials: G
authors.lastname: Rabolini
authors.forename: Márcio
authors.initials: M
authors.lastname: Menna-Barreto
authors.forename: Emanuel B
authors.initials: EB
authors.lastname: Dos Santos
authors.forename: Walter J
authors.initials: WJ
authors.lastname: Koff