title: [Subaortic stenosis associated with perimembranous ventricular septal defect. Clinical follow-up of 36 patients].
abstract: OBJECTIVE
  To study the clinical pattern of subaortic stenosis associated with perimembranous ventricular septal defect.
  
  
  METHODS
  From January 1979 to June 2000, 36 children with perimembranous ventricular septal defect and fixed subaortic stenosis were followed-up regarding anatomic characteristics, evolvement, and clinical events.
  
  
  RESULTS
  Age at diagnosis of subaortic stenosis ranged from 6 months to 170 months, and it was less than 1 year in only 2 children. Regarding sex, the distribution was 2:1 with a greater predominance of males. Ventricular septal defect was small in 61.0% of cases, medium in 30.56%, and large in 8.40%; the size of the septal defect decreased during follow-up in 30.56% (11 cases). In all patients, subaortic stenosis was membranous and fixed. During follow-up, 23 patients experienced evolvement of the stenosis. Surgical treatment was performed in 21 cases, and one patient underwent surgery for restenosis. Infectious endocarditis occurred in 2 patients; one of the patients died.
  
  
  CONCLUSIONS
  Subaortic stenosis occurs in the natural history of ventricular septal defect usually after the first year of life, and it is progressive and requires surgery in most cases.
authors.affiliation: Faculdade de Medicina, UFMG, Santa Casa de Misericórdia de Belo Horizonte, Belo Horizonte, MG. mgchorta@hotmail.com
authors.forename: Maria da Gloria Cruvinel
authors.initials: Mda G
authors.lastname: Horta
authors.forename: Carlos Alberto Franco
authors.initials: CA
authors.lastname: Faria
authors.forename: Dilermando Fazito
authors.initials: DF
authors.lastname: Rezende
authors.forename: Tereza Lucia
authors.initials: TL
authors.lastname: Masci
authors.forename: Cathia Costa C
authors.initials: CC
authors.lastname: Rabelo
authors.forename: Tamara
authors.initials: T
authors.lastname: Katina
authors.forename: Marly de
authors.initials: Md
authors.lastname: Oliveira
authors.forename: Luciana Paulino
authors.initials: LP
authors.lastname: Oliveira
mesh_terms: D000293:Adolescent; D000790:Angiocardiography; D001020:Aortic Stenosis, Subvalvular / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006345:Heart Septal Defects, Ventricular / Q000150:complications* / Q000601:surgery; D006801:Humans; D007223:Infant; D008297:Male; D012720:Severity of Illness Index