title: Evolution of serum alpha-tocopherol in the postprandial and postabsorptive phases in type 1 diabetes mellitus.
abstract: Blood glucose, lipids, alpha-tocopherol, and malondialdehyde were monitored in type 1 diabetes mellitus patients for 8 hours after a standard fat-rich breakfast and lunch. Although glucose and triglycerides increased, alpha-tocopherol decreased and malondialdehyde increased in the postprandial phase. In the postabsorptive phase values returned to fasting levels. These results point to the possible relevance of postprandial alpha-tocopherol depletion and lipid peroxidation to an increased cardiovascular risk in these patients.
authors.affiliation: University of Antwerp (UA) campus Drie Eiken, Metabolic Research Unit (AMRU) T4.37, Universiteitsplein 1, B-2610 Wilrijk-Antwerp, Belgium. begona.manuelykeenoy@ua.ac.be
authors.forename: Begoña
authors.initials: B
authors.lastname: Manuel-y-Keenoy
authors.forename: Ann
authors.initials: A
authors.lastname: Van Campenhout
authors.forename: Jan
authors.initials: J
authors.lastname: Vertommen
authors.forename: Luc
authors.initials: L
authors.lastname: Van Gaal
authors.forename: Ivo
authors.initials: I
authors.lastname: De Leeuw
mesh_terms: D000042:Absorption; D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D005260:Female; D005502:Food; D006801:Humans; D007700:Kinetics; D008055:Lipids / Q000097:blood; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood; D024502:alpha-Tocopherol / Q000097:blood*
chemical_list: D001786:Blood Glucose; D008055:Lipids; D014280:Triglycerides; D008315:Malondialdehyde; D024502:alpha-Tocopherol