New hemiketal steroid from the soft coral Cladiella sp.
[structure: see text] A new hemiketal steroid, named cladiellin A (1), was first isolated from the soft coral Cladiella sp. Its structure was determined by spectroscopic methods and X-ray analysis. Compound 1 easily converted to 1a when NMR spectra were measured in CDCl(3) solution and quickly changed to 1b when pyridine was used. The structures of dehydrated products 1a and 1b were determined by spectroscopic analysis. Bioassay showed that all these three compounds showed antioxidant activity.
Zhang
Guang-Wen
GW
School of Chemistry and Chemical Engineering, Sun Yat-Sen (Zhongshan) University, Guangzhou 510275, China.
Ma
Xiang-Quan
XQ
Kurihara
Hiroshi
H
Zhang
Cui-Xian
CX
Yao
Xin-Sheng
XS
Su
Jing-Yu
JY
Zeng
Long-Mei
LM
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018360:Crystallography, X-Ray; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000975:Antioxidants; D013256:Steroids; C506145:cladiellin A