title: MIPS bacterial genomes functional annotation benchmark dataset.
abstract: BACKGROUND
  Any development of new methods for automatic functional annotation of proteins according to their sequences requires high-quality data (as benchmark) as well as tedious preparatory work to generate sequence parameters required as input data for the machine learning methods. Different program settings and incompatible protocols make a comparison of the analyzed methods difficult.
  
  
  RESULTS
  The MIPS Bacterial Functional Annotation Benchmark dataset (MIPS-BFAB) is a new, high-quality resource comprising four bacterial genomes manually annotated according to the MIPS functional catalogue (FunCat). These resources include precalculated sequence parameters, such as sequence similarity scores, InterPro domain composition and other parameters that could be used to develop and benchmark methods for functional annotation of bacterial protein sequences. These data are provided in XML format and can be used by scientists who are not necessarily experts in genome annotation.
  
  
  BACKGROUND
  BFAB is available at http://mips.gsf.de/proj/bfab
authors.affiliation: Institute for Bioinformatics (MIPS), GSF National Research Center for Environment and Health, Ingolstaedter Landstrasse 1, D-85764 Neuherberg, Germany. i.tetko@gsf.de
authors.forename: Igor V
authors.initials: IV
authors.lastname: Tetko
authors.forename: Barbara
authors.initials: B
authors.lastname: Brauner
authors.forename: Irmtraud
authors.initials: I
authors.lastname: Dunger-Kaltenbach
authors.forename: Goar
authors.initials: G
authors.lastname: Frishman
authors.forename: Corinna
authors.initials: C
authors.lastname: Montrone
authors.forename: Gisela
authors.initials: G
authors.lastname: Fobo
authors.forename: Andreas
authors.initials: A
authors.lastname: Ruepp
authors.forename: Alexey V
authors.initials: AV
authors.lastname: Antonov
authors.forename: Dimitrij
authors.initials: D
authors.lastname: Surmeli
authors.forename: Hans-Wernen
authors.initials: HW
authors.lastname: Mewes
mesh_terms: D001426:Bacterial Proteins / Q000737:chemistry* / Q000145:classification / Q000235:genetics*; D019985:Benchmarking / Q000379:methods*; D002874:Chromosome Mapping / Q000379:methods*; D003628:Database Management Systems; D030562:Databases, Protein; D004282:Documentation / Q000379:methods*; D016680:Genome, Bacterial; D016247:Information Storage and Retrieval / Q000379:methods; D020407:Internet
chemical_list: D001426:Bacterial Proteins