Terphenyl-based helical mimetics that disrupt the p53/HDM2 interaction.
Yin
Hang
H
Department of Chemistry, Yale University, P.O. Box 208 107, New Haven, CT 06520-8107, USA, Fax: (+1) 203-432-6144.
Lee
Gui-In
GI
Department of Chemistry, Yale University, P.O. Box 208 107, New Haven, CT 06520-8107, USA, Fax: (+1) 203-432-6144.
Park
Hyung Soon
HS
Department of Chemistry, Yale University, P.O. Box 208 107, New Haven, CT 06520-8107, USA, Fax: (+1) 203-432-6144.
Payne
Gregory A
GA
Department of Chemistry, Yale University, P.O. Box 208 107, New Haven, CT 06520-8107, USA, Fax: (+1) 203-432-6144.
Rodriguez
Johanna M
JM
Department of Chemistry, Yale University, P.O. Box 208 107, New Haven, CT 06520-8107, USA, Fax: (+1) 203-432-6144.
Sebti
Said M
SM
Drug Discovery Program, H. Lee Moffitt Cancer Center and Research Institute, Departments of Oncology and Biochemistry and Molecular Biology, University of South Florida, Tampa, FL 33612, USA.
Hamilton
Andrew D
AD
Department of Chemistry, Yale University, P.O. Box 208 107, New Haven, CT 06520-8107, USA, Fax: (+1) 203-432-6144.
D040761:Biomimetic Materials / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D018360:Crystallography, X-Ray; D006801:Humans; D008958:Models, Molecular; D019906:Nuclear Magnetic Resonance, Biomolecular; D011485:Protein Binding / Q000187:drug effects; D020836:Protein Structure, Quaternary; D051736:Proto-Oncogene Proteins c-mdm2 / Q000037:antagonists & inhibitors / Q000378:metabolism*; D013730:Terphenyl Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D016159:Tumor Suppressor Protein p53 / Q000037:antagonists & inhibitors / Q000378:metabolism*
D013730:Terphenyl Compounds; D016159:Tumor Suppressor Protein p53; C497206:MDM2 protein, human; D051736:Proto-Oncogene Proteins c-mdm2