title: Hit to Lead Success Stories--IBC Conference: Effective chemistry strategies for reducing attrition rates and speeding lead compounds into the pipeline. 31 January-1 February 2005, San Diego, CA, USA.
authors.affiliation: Aventis Pharmaceuticals Germany, Industrial Park Hoechst, D-65926 Frankfurt am Main, Frankfurt, Germany. peter.nestler@sanofi-aventis.com
authors.forename: H Peter
authors.initials: HP
authors.lastname: Nestler
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry / Q000627:therapeutic use; D001920:Bradykinin / Q000031:analogs & derivatives / Q000737:chemistry / Q000627:therapeutic use; D017277:Drug Approval / Q000379:methods*; D015195:Drug Design; D004341:Drug Evaluation / Q000379:methods / Q000639:trends; D006801:Humans; D015394:Molecular Structure; D010880:Piperidines / Q000737:chemistry / Q000627:therapeutic use; D011422:Propionates / Q000737:chemistry / Q000627:therapeutic use; D011725:Pyridines / Q000737:chemistry / Q000627:therapeutic use; D013997:Time Factors; D003986:Dibenzocycloheptenes
chemical_list: D000814:Aniline Compounds; D001920:Bradykinin; D010880:Piperidines; D011422:Propionates; D011725:Pyridines; C065679:icatibant; C115354:lonafarnib; D003986:Dibenzocycloheptenes; C067396:efaproxiral