title: Treatment options for osteoarthritis.
abstract: Osteoarthritis is the most common form of arthritis and can be a major source of disability. Many older patients continue to be active in sports-related activities. Therefore, treating an active patient with osteoarthritis is becoming more common. Physical therapy and weight loss continue to play a central role in the treatment of patients with osteoarthritis. Nonsteroidal anti-inflammatory drugs decrease inflammation and swelling, which makes physical therapy more effective. Intra-articular corticosteroids have been used for the treatment of osteoarthritis. However, no guidelines exist for the administration of corticosteroids and they can be associated with increased risk of tendon rupture and infection. Viscosupplementation has gained popularity in the treatment of osteoarthritis of the knee. Intra-articular injections of hyaluronic acid have been shown to decrease pain and improve functional outcomes.
authors.affiliation: Beverly Hills Orthopedic Group, Beverly Hills, Calif, USA.
authors.forename: Jason C
authors.initials: JC
authors.lastname: Snibbe
authors.forename: Ralph A
authors.initials: RA
authors.lastname: Gambardella
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage* / Q000493:pharmacokinetics; D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D016861:Cyclooxygenase Inhibitors / Q000627:therapeutic use; D005081:Exercise Therapy; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage* / Q000493:pharmacokinetics; D007270:Injections, Intra-Articular; D010003:Osteoarthritis / Q000188:drug therapy* / Q000628:therapy; D020370:Osteoarthritis, Knee / Q000628:therapy; D015431:Weight Loss
chemical_list: D000276:Adjuvants, Immunologic; D000305:Adrenal Cortex Hormones; D000894:Anti-Inflammatory Agents, Non-Steroidal; D016861:Cyclooxygenase Inhibitors; D006820:Hyaluronic Acid