[A drop in "apparent" blood viscosity due to administration of high-molecular polymer capable of augmenting viscosity].
Influence of a high-molecular compound capable of augmenting viscosity, namely: polyethylene oxide Polyox WSR-301, on hemodynamic parameters in rat mesenteric microvessels was investigated. A substantial decrease in the arteriolar hemodynamic resistance caused by the polymer was revealed. Special research has shown that this reaction is not connected with a vasodilatation and, therefore, is caused by a reduction in the "apparent" viscosity of the blood, i.e., it is a consequence of changed properties of the blood flow.
Grigorian
S S
SS
Sokolova
I A
IA
Shakhnazarov
A A
AA
Timkina
M I
MI
Proskurin
S G
SG
Priezzhev
A V
AV
D000818:Animals; D001783:Blood Flow Velocity / Q000187:drug effects; D001809:Blood Viscosity / Q000187:drug effects*; D018056:Hemorheology; D007422:Intestines / Q000098:blood supply*; D008297:Male; D008638:Mesenteric Arteries / Q000502:physiology; D008642:Mesenteric Veins / Q000502:physiology; D008833:Microcirculation / Q000187:drug effects; D011092:Polyethylene Glycols / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D014655:Vascular Resistance / Q000187:drug effects
C098305:Polyox WSR-301; D011092:Polyethylene Glycols