[Sildenafil improves right ventricular function in a cardiac transplant recipient].
We report the case of a male patient who underwent orthotopic cardiac transplantation. A marginal donor was used, because the recipient's clinical condition was critical. He experienced cardiogenic shock due to right ventricular dysfunction secondary to pulmonary hypertension associated with vasoplegia. After the introduction of sildenafil, the patient recovered hemodynamically, his pulmonary vascular resistance decreased, the vasoactive drugs were withdrawn, and his right ventricular function improved.
Paez
Rodrigo Pereira
RP
Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP. rppaez@yahoo.com.br
Araujo
Wesley Ferreira
WF
Hossne
Nelson Americo
NA
Neves
Ana Lucia
AL
Vargas
Guilherme Flora
GF
Aguiar
Luciano de Figueiredo
Lde F
Branco
João Nelson Rodrigues
JN
Catani
Roberto
R
Buffolo
Enio
E
D000328:Adult; D016027:Heart Transplantation; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy*; D008297:Male; D010879:Piperazines / Q000627:therapeutic use*; D011687:Purines; D000068677:Sildenafil Citrate; D013450:Sulfones; D014655:Vascular Resistance / Q000187:drug effects / Q000502:physiology; D014665:Vasodilator Agents / Q000627:therapeutic use*; D016278:Ventricular Function, Right / Q000187:drug effects* / Q000502:physiology
D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate