Re-analysis of data and its integration.
To understand a biological process it is clear that a single approach will not be sufficient, just like a single measurement on a protein--such as its expression level--does not describe protein function. Using reference sets of proteins as benchmarks different approaches can be scaled and integrated. Here, we demonstrate the power of data re-analysis and integration by applying it in a case study to data from deletion phenotype screens and mRNA expression profiling.
Jensen
Lars Juhl
LJ
European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.
Steinmetz
Lars M
LM
D019295:Computational Biology; D030541:Databases, Genetic; D020869:Gene Expression Profiling; D008954:Models, Biological; D010641:Phenotype; D011506:Proteins / Q000235:genetics* / Q000502:physiology; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000502:physiology
D011506:Proteins