title: The Ilizarov method in the treatment of malignant neoplasms of the tibia.
abstract: A total of 3 malignant neoplasms of the tibia are presented: 1 is a mesenchymal chondrosarcoma of the tibial pylon (male aged 14 years), and 2 are cases of squamous skin carcinoma of the leg with tibial infiltration (1 male and 1 female aged 32 and 64 years, respectively). The resections carried out (16.5 cm on the average) were treated by bone transport. Simple transport was used in the first patient, double in the other two. At the end of transport a second surgical stage involving astragalotibial arthrodesis was performed in the first case, and revision of the junction site of bone segments transported with application of autoplastic bone grafts was performed in the other two. The regenerate obtained was slowly corticalized in the first patient, submitted to various cycles of chemotherapy during the course of distraction. In the other two cases, which were not treated by chemotherapy during distraction, corticalization occurred over a shorter amount of time. Follow-up was obtained after 10 years in the first case, and after 2 years in the other 2 patients. There was no long-term recurrence.
authors.affiliation: Università degli Studi di Padova, Dipartimento di Specialità Medico-Chirurgiche, Clinica Ortopedica e Traumatologica.
authors.forename: C
authors.initials: C
authors.lastname: Iacobellis
authors.forename: A
authors.initials: A
authors.lastname: Olmeda
mesh_terms: D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001174:Arthrodesis; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D016025:Bone Transplantation; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D018211:Chondrosarcoma, Mesenchymal / Q000601:surgery*; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D018889:Ilizarov Technique; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D019857:Osteogenesis, Distraction; D010027:Osteotomy; D011859:Radiography; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology; D013977:Tibia; D013997:Time Factors; D014182:Transplantation, Autologous; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin