Selective guanine oxidation by UVB-irradiation in telomeric DNA.
The combination of the transient absorption measurement and DNA damage quantification by HPLC clearly demonstrated the preferential excitation of guanine and its decomposition in quadruplex DNA by UVB-irradiation.
Kawai
Kiyohiko
K
The Institute of Scientific and Industrial Research (SANKEN), Osaka University, Address Mihogaoka 8-1, Ibaraki, Osaka, 567-0047, Japan. kiyohiko@sanken.osaka-u.ac.jp
Fujitsuka
Mamoru
M
Majima
Tetsuro
T
D004247:DNA / Q000737:chemistry / Q000528:radiation effects*; D006147:Guanine / Q000737:chemistry* / Q000528:radiation effects*; D010084:Oxidation-Reduction; D016615:Telomere / Q000737:chemistry / Q000528:radiation effects*; D014466:Ultraviolet Rays
D006147:Guanine; D004247:DNA