Med-psych drug-drug interactions update. Antiretrovirals, part III: antiretrovirals and drugs of abuse.
The third in a series reviewing the HIV/AIDS antiretroviral drugs, this report summarizes the interactions between antiretrovirals and common drugs of abuse. In an overview format for primary care physicians and psychiatrists, the metabolism and drug interactions in the context of antiretroviral therapy are presented for the following drugs of abuse: alcohol, benzodiazepines, cocaine, GHB (liquid X), ketamine (special K), LSD (acid), MDMA (Ecstasy), opiates, PCP (angel dust), and THC (marijuana).
Wynn
Gary H
GH
Uniformed Services University of the Health Sciences, F Edward Hebert School of Medicine, Bethesda, MD, USA.
Cozza
Kelly L
KL
Zapor
Michael J
MJ
Wortmann
Glenn W
GW
Armstrong
Scott C
SC
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D044966:Anti-Retroviral Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004347:Drug Interactions; D004790:Enzyme Induction / Q000187:drug effects; D015658:HIV Infections / Q000188:drug therapy* / Q000201:enzymology; D006801:Humans; D013287:Illicit Drugs / Q000009:adverse effects* / Q000493:pharmacokinetics; D010349:Patient Compliance; D010353:Patient Education as Topic
D044966:Anti-Retroviral Agents; D013287:Illicit Drugs; D003577:Cytochrome P-450 Enzyme System