Preimplantation sex selection demand and preferences in an infertility population.
OBJECTIVE
To determine the demand and preferences of infertility patients for sex selection and the method and sex they would choose, and to investigate the relationship between these choices and their demographic and socioeconomic characteristics.


METHODS
Cross-sectional survey.


METHODS
University hospital-based fertility center.


METHODS
One thousand five hundred consecutive women who presented for infertility care.


METHODS
None.


METHODS
Self-report questionnaire assessing the demand and preferences for sex selection.


RESULTS
Of respondents, 40.8% wanted to select the sex of their next child for no added cost. Of these patients, 45.9% had no living children and 48.4% had children all of one sex. After adjustment for observed predictors of gender preference, we found a significant preference for a female child among women who were older, not religious, willing to pay for sex selection, had more living children, had only sons, or had a diagnosis of male infertility. Nulliparous women did not significantly prefer one sex over the other. Among parous women, those with only daughters significantly desired to select a male child, whereas those with sons significantly desired to select a female child. In terms of the method of sex selection, 55.0%, 41.0%, and 4.0% of the patients would use sperm separation, preimplantation genetic diagnosis, or neither method, respectively.


CONCLUSIONS
There is significant demand among infertility patients for preimplantation sex selection, with a significant portion of this demand coming from patients who do not have any children or have children all of one sex.
Jain
Tarun
T
Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. tjain@uic.edu
Missmer
Stacey A
SA
Gupta
Raina S
RS
Hornstein
Mark D
MD
D000328:Adult; D001755:Blastocyst; D003430:Cross-Sectional Studies; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods / Q000523:psychology*; D006801:Humans; D007246:Infertility / Q000523:psychology* / Q000628:therapy; D008297:Male; D017060:Patient Satisfaction; D011177:Postal Service; D012743:Sex Preselection / Q000523:psychology* / Q000706:statistics & numerical data; D012923:Social Class; D011795:Surveys and Questionnaires; D014481:United States