Arabidopsis epigenetics: when RNA meets chromatin.
Recent work in plants and other eukaryotes has uncovered a major role for RNA interference in silent chromatin formation. The heritability of the silent state through multiple cell division cycles and, in some instances, through meiosis is assured by epigenetic marks. In plants, transposable elements and transgenes provide striking examples of the stable inheritance of repressed states, and are characterized by dense DNA methylation and heterochromatin histone modifications. Arabidopsis is a useful higher eukaryotes model with which to explore the crossroads between silent chromatin and RNA interference both during development and in the genome-wide control of repeat elements.
Gendrel
Anne-Valérie
AV
Unité de Recherche en Génomique Végétale, INRA/CNRS/UEVE, 2 rue Gaston Crémieux, 91057 Evry Cedex, France.
Colot
Vincent
V
D017360:Arabidopsis / Q000235:genetics*; D002843:Chromatin / Q000235:genetics*; D019175:DNA Methylation; D018744:DNA, Plant / Q000235:genetics; D014644:Genetic Variation; D006657:Histones / Q000235:genetics / Q000378:metabolism; D034622:RNA Interference; D018749:RNA, Plant / Q000235:genetics*
D002843:Chromatin; D018744:DNA, Plant; D006657:Histones; D018749:RNA, Plant