title: [ATPase subunit 6 gene of Leptomonas seymouri (Trypanosomatidae) is transcribed and edited as a polycistronic transcript].
abstract: The maturation of mitochondrial RNA transcripts proceeds through several steps. Here we use insects trypanosomatid Leptomonas seymouri as a model organism for analysis of transcription and posttranscriptional processing of mitochondria encoded gene for the subunit 6 of ATPase (A6). It was shown that Cyt b (cytochrome b) and A6 genes were transcribed and edited as a polycistronic template. Analysis of twelve RT-PCR products of both genes led to identification of four types of differently and/or partially edited cDNA molecules. Based on the analysis of two fully edited A6 transcripts we propose the existence of two alternatively edited products.
authors.forename: E A
authors.initials: EA
authors.lastname: Bessolitsyna
authors.forename: A V
authors.initials: AV
authors.lastname: Fediakov
authors.forename: E M
authors.initials: EM
authors.lastname: Merzliak
authors.forename: A A
authors.initials: AA
authors.lastname: Kolesnikov
mesh_terms: D000251:Adenosine Triphosphatases / Q000235:genetics*; D000818:Animals; D001483:Base Sequence; D045303:Cytochromes b / Q000235:genetics; D016054:DNA, Protozoan / Q000235:genetics; D008928:Mitochondria / Q000235:genetics; D008969:Molecular Sequence Data; D021122:Protein Subunits / Q000235:genetics; D012313:RNA / Q000235:genetics*; D017393:RNA Editing; D012333:RNA, Messenger / Q000235:genetics*; D000077278:RNA, Mitochondrial; D016053:RNA, Protozoan / Q000235:genetics*; D014158:Transcription, Genetic; D014351:Trypanosomatina / Q000235:genetics*
chemical_list: D016054:DNA, Protozoan; D021122:Protein Subunits; D012333:RNA, Messenger; D000077278:RNA, Mitochondrial; D016053:RNA, Protozoan; D012313:RNA; D045303:Cytochromes b; D000251:Adenosine Triphosphatases