title: Spatial selectivity in human ventrolateral prefrontal cortex.
abstract: The functional organization of lateral prefrontal cortex is not well understood, and there is debate as to whether the dorsal and ventral aspects mediate distinct spatial and non-spatial functions, respectively. We show for the first time that recordings from human ventrolateral prefrontal cortex show spatial selectivity, supporting the idea that ventrolateral prefrontal cortex is involved in spatial processing. Our results also indicate that prefrontal cortex may be a source of control signals for neuroprosthetic applications.
authors.affiliation: Division of Biology, California Institute of Technology, 1200 East California Blvd., Pasadena, California 91125, USA.
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Rizzuto
authors.forename: Adam N
authors.initials: AN
authors.lastname: Mamelak
authors.forename: William W
authors.initials: WW
authors.lastname: Sutherling
authors.forename: Igor
authors.initials: I
authors.lastname: Fineman
authors.forename: Richard A
authors.initials: RA
authors.lastname: Andersen
mesh_terms: D001931:Brain Mapping; D002755:Choice Behavior / Q000502:physiology*; D004566:Electrodes; D004569:Electroencephalography / Q000379:methods; D005071:Evoked Potentials / Q000502:physiology; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D009068:Movement / Q000502:physiology; D017397:Prefrontal Cortex / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D013028:Space Perception / Q000502:physiology*; D013057:Spectrum Analysis