title: Tc-99m MDP bone scintigraphy of myositis as a manifestation of chronic graft-versus-host disease after non-myeloablative peripheral stem cell transplantation.
abstract: A 27-year-old man developed polymyositis as a manifestation of chronic graft-versus-host disease (GVHD) after non-myeloablative peripheral blood stem cell transplantation (PBSCT). Bone scintigraphy showed intense, striped, and heterogeneous accumulation of Tc-99m methylene diphosphonate (MDP) in the soft-tissue of his lower limbs, while faint activities were seen in the right upper limb. Tc-99m MDP scintigraphy was very useful for accurate and objective evaluation of the severity of the muscle injury and the extent of polymyositis caused by chronic GVHD.
authors.affiliation: Department of Medical Imaging, Sapporo City General Hospital, Japan.
authors.forename: Maki
authors.initials: M
authors.lastname: Mitomo
authors.forename: Chihoko
authors.initials: C
authors.lastname: Miyazaki
authors.forename: Masaya
authors.initials: M
authors.lastname: Mukai
authors.forename: Yohko
authors.initials: Y
authors.lastname: Usami
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Nagano
authors.forename: Noriko
authors.initials: N
authors.lastname: Nakamura
authors.forename: Kohzoh
authors.initials: K
authors.lastname: Kubo
mesh_terms: D000328:Adult; D001842:Bone and Bones / Q000000981:diagnostic imaging; D005121:Extremities / Q000000981:diagnostic imaging; D006086:Graft vs Host Disease / Q000150:complications* / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D009220:Myositis / Q000000981:diagnostic imaging* / Q000209:etiology*; D036102:Peripheral Blood Stem Cell Transplantation / Q000009:adverse effects*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate
chemical_list: D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate