title: [Quantitative morphometry of hyperplastic hypoechoic nodules in the prostatic outer gland].
abstract: OBJECTIVE
  To explore the morphotic characteristics of hypoechoic nodules in the outer gland of the prostate with benign
  
  
  METHODS
  Twenty-two hyperplastic hypoechoic nodules in the prostatic outer gland were biopsied guided by prostatic hyperplasia. transrectal ultrasound. The hematoxylin-eosin (HE) staining and immunohistochemistry combined with computer assisted quantitative image analyses were adopted to examine the mean percentages of the area densities of stroma, epithelium, glandular lumen and smooth muscle cells.
  
  
  RESULTS
  The area densities of stroma, epithelium, glandular lumen and smooth muscle cells were (72.52 +/- 13.14)%, (20.57 +/- 9.01)%, (6.85 +/- 4.51)% and (24.14 +/- 6.31)%, respectively.
  
  
  CONCLUSIONS
  Hyperplastic hypoechoic nodules may develop in the outer gland as well as in the inner gland of the prostate, but the mean percentages of the components are different between the two kinds of nodules.
authors.affiliation: Department of Ultrasonics, General Hospital of PLA, Beijing 100853, China. lx0803@sina.com.en
authors.forename: Xin
authors.initials: X
authors.lastname: Li
authors.forename: Na
authors.initials: N
authors.lastname: Wang
authors.forename: Huai-Yin
authors.initials: HY
authors.lastname: Shi
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xian-Shui
authors.initials: XS
authors.lastname: Fu
authors.forename: Jun-Lai
authors.initials: JL
authors.lastname: Li
authors.forename: Jian-Hong
authors.initials: JH
authors.lastname: Xu
authors.forename: Jie
authors.initials: J
authors.lastname: Tang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D004848:Epithelium / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009130:Muscle, Smooth / Q000000981:diagnostic imaging / Q000473:pathology; D011467:Prostate / Q000000981:diagnostic imaging / Q000473:pathology*; D011470:Prostatic Hyperplasia / Q000000981:diagnostic imaging / Q000473:pathology*; D014463:Ultrasonography