title: False-positive Histoplasma capsulatum Gen-Probe chemiluminescent test result caused by a Chrysosporium species.
abstract: We describe a case in which the Histoplasma capsulatum AccuProbe test displayed cross-reactivity with a respiratory isolate thought to be Histoplasma but not morphologically consistent with H. capsulatum. The isolate was later identified as the Chrysosporium anamorph of Nannizziopsis vriesii by sequence analysis and phenotypic data.
authors.affiliation: Mycotic Diseases Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, Mail Stop G-11, Atlanta, GA 30333, USA. mbb4@cdc.gov
authors.forename: Mary E
authors.initials: ME
authors.lastname: Brandt
authors.forename: Dennis
authors.initials: D
authors.lastname: Gaunt
authors.forename: Naureen
authors.initials: N
authors.lastname: Iqbal
authors.forename: Shirley
authors.initials: S
authors.lastname: McClinton
authors.forename: Sarah
authors.initials: S
authors.lastname: Hambleton
authors.forename: Lynne
authors.initials: L
authors.lastname: Sigler
mesh_terms: D000328:Adult; D001483:Base Sequence; D002912:Chrysosporium / Q000302:isolation & purification*; D005189:False Positive Reactions; D006658:Histoplasma / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008163:Luminescent Measurements; D008297:Male; D008969:Molecular Sequence Data; D010641:Phenotype; D017422:Sequence Analysis, DNA