title: Metabolic consequences and long-term complications of enterocystoplasty in children: a review.
abstract: OBJECTIVE
  We summarize important metabolic consequences and long-term complications associated with enterocystoplasty with particular emphasis on the pediatric patient with genitourinary abnormalities.
  
  
  METHODS
  A directed MEDLINE literature review for metabolic and long-term complications following enterocystoplasty was performed. Information gained through the published literature and from our database was reviewed and summarized to provide the reader with a thorough review of the subject.
  
  
  RESULTS
  Bowel is not a perfect tissue for substitution or augmentation and its use to treat functionally and structurally compromised bladders is associated with several metabolic consequences and long-term complications. Metabolic acidosis is the most common metabolic abnormality seen. The rates and severity of these complications vary, although they may have a profound impact on patient quality of life after enterocystoplasty.
  
  
  CONCLUSIONS
  The metabolic consequences and long-term complications associated with enterocystoplasty are important clinical features of this intervention. Careful consideration should be given to them prior to pursuing enterocystoplasty.
authors.affiliation: Department of Urology, Division of Pediatric Urology, Children's Hospital of New York, Columbia University Medical Center, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.
authors.forename: Scott M
authors.initials: SM
authors.lastname: Gilbert
authors.forename: Terry W
authors.initials: TW
authors.lastname: Hensle
mesh_terms: D002648:Child; D006801:Humans; D007422:Intestines / Q000601:surgery; D008659:Metabolic Diseases / Q000209:etiology*; D011183:Postoperative Complications; D011788:Quality of Life; D016896:Treatment Outcome; D001743:Urinary Bladder / Q000601:surgery; D014547:Urinary Diversion / Q000009:adverse effects*