title: [Assessment of regional myocardial systolic function in hypertensive left ventricular hypertrophy using harmonic myocardial strain imaging].
abstract: OBJECTIVE
  Regional myocardial systolic function in hypertensive left ventricular hypertrophy was assessed using the newly developed myocardial strain imaging.
  
  
  METHODS
  This study included 17 patients with hypertensive left ventricular hypertrophy (LVH group) and 22 normal subjects (N group). The transmural location of the strain peak value (StPP), and the strain peak value (StPV) in the end-systolic phase were measured at the posterior wall by myocardial strain imaging. Left ventricular mass index was simultaneously measured in both groups.
  
  
  RESULTS
  StPV was significantly lower in the LVH group than the N group (1.00 +/- 0.36 vs 1.38 +/- 0.42, p < 0.01) and StPP was significantly moved to the epicardium side compared with the N group (31 +/- 10% vs 11 +/- 5%, p < 0.0001). StPV decreased and StPP increased with greater left ventricular mass index (r = -0.61, p < 0.0001; r = 0.72, p < 0.0001, respectively).
  
  
  CONCLUSIONS
  Myocardial systolic impairment in hypertensive left ventricular hypertrophy may occur from the endocardium side, and the impairment may progress with increased left ventricular hypertrophy.
authors.affiliation: The Second Department of Internal Medicine, Tokyo Medical University, Tokyo. maki-m@cj8.so-net.ne.jp
authors.forename: Maki
authors.initials: M
authors.lastname: Manaka
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Tanaka
authors.forename: Yasuyoshi
authors.initials: Y
authors.lastname: Takei
authors.forename: Saiko
authors.initials: S
authors.lastname: Kurohane
authors.forename: Kenji
authors.initials: K
authors.lastname: Takazawa
authors.forename: Akira
authors.initials: A
authors.lastname: Yamashina
mesh_terms: D000368:Aged; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000503:physiopathology; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D013318:Stroke Volume; D013599:Systole