title: Treatment of empty sella syndrome with ventriculoperitoneal shunt.
abstract: A symptomatic empty sella developed in a female patient undergoing bromocriptine therapy for microprolactinoma. Placement of a ventriculoperitoneal shunt dramatically improved the symptoms of headache and blurred vision. The post-operative imaging showed resolution of the empty sella. She was able to resume bromocriptine therapy without recurrence of her previous symptoms and give birth to a baby 20 months later. An MRI 44 months after surgery and on bromocriptine therapy showed no recurrence of the empty sella. We conclude that ventriculoperitoneal shunt may be a simple, and durable treatment for drug induced empty sella and allows resumption of bromocriptine therapy for preexisting microprolactinoma.
authors.affiliation: Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital, Tajen Institute of Technology, Pingtong, Taiwan. leet@adm.cgmh.org.tw
authors.forename: Tao-Chen
authors.initials: TC
authors.lastname: Lee
authors.forename: Lin-Cheng
authors.initials: LC
authors.lastname: Yang
authors.forename: Pao-Lin
authors.initials: PL
authors.lastname: Huang
mesh_terms: D000328:Adult; D001971:Bromocriptine / Q000009:adverse effects*; D004652:Empty Sella Syndrome / Q000139:chemically induced* / Q000601:surgery*; D005260:Female; D006727:Hormone Antagonists / Q000009:adverse effects*; D006801:Humans; D008279:Magnetic Resonance Imaging; D010911:Pituitary Neoplasms / Q000188:drug therapy; D015175:Prolactinoma / Q000188:drug therapy; D017287:Ventriculoperitoneal Shunt
chemical_list: D006727:Hormone Antagonists; D001971:Bromocriptine