title: The first total synthesis of (-)-methyl barbascoate.
abstract: [reaction: see text] The neo-trans-clerodane natural product, (-)-methyl barbascoate 1, has been synthesized for the first time starting from the known ketone 6 derived from (R)-(-)-Wieland-Miescher ketone analogue 5.
authors.affiliation: Graduate School of Science and Technology, Niigata University, 8050, 2-Nocho, Ikarashi, Niigata 950-2181, Japan. hagiwara@gs.niigata-u.ac.jp
authors.forename: Hisahiro
authors.initials: H
authors.lastname: Hagiwara
authors.forename: Kenta
authors.initials: K
authors.lastname: Hamano
authors.forename: Masato
authors.initials: M
authors.lastname: Nozawa
authors.forename: Takashi
authors.initials: T
authors.lastname: Hoshi
authors.forename: Toshio
authors.initials: T
authors.lastname: Suzuki
authors.forename: Fusao
authors.initials: F
authors.lastname: Kido
mesh_terms: D005663:Furans / Q000138:chemical synthesis*; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis*; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry*; D008968:Molecular Conformation; D013237:Stereoisomerism
chemical_list: D005663:Furans; D006575:Heterocyclic Compounds, 3-Ring; D007659:Ketones; C500921:methyl barbascoate