title: wFleaBase: the Daphnia genome database.
abstract: BACKGROUND
  wFleaBase is a database with the necessary infrastructure to curate, archive and share genetic, molecular and functional genomic data and protocols for an emerging model organism, the microcrustacean Daphnia. Commonly known as the water-flea, Daphnia's ecological merit is unequaled among metazoans, largely because of its sentinel role within freshwater ecosystems and over 200 years of biological investigations. By consequence, the Daphnia Genomics Consortium (DGC) has launched an interdisciplinary research program to create the resources needed to study genes that affect ecological and evolutionary success in natural environments.
  
  
  CONCLUSIONS
  These tools include the genome database wFleaBase, which currently contains functions to search and extract information from expressed sequenced tags, genome survey sequences and full genome sequencing projects. This new database is built primarily from core components of the Generic Model Organism Database project, and related bioinformatics tools.
  
  
  CONCLUSIONS
  Over the coming year, preliminary genetic maps and the nearly complete genomic sequence of Daphnia pulex will be integrated into wFleaBase, including gene predictions and ortholog assignments based on sequence similarities with eukaryote genes of known function. wFleaBase aims to serve a large ecological and evolutionary research community. Our challenge is to rapidly expand its content and to ultimately integrate genetic and functional genomic information with population-level responses to environmental challenges. URL: http://wfleabase.org/.
authors.affiliation: Center for Genomics and Bioinformatics, Indiana University, Bloomington, Indiana, USA. jcolbour@cgb.indiana.edu
authors.forename: John K
authors.initials: JK
authors.lastname: Colbourne
authors.forename: Vasanth R
authors.initials: VR
authors.lastname: Singan
authors.forename: Don G
authors.initials: DG
authors.lastname: Gilbert
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D019295:Computational Biology / Q000379:methods*; D003196:Computer Graphics; D003621:Daphnia / Q000235:genetics*; D003628:Database Management Systems; D016208:Databases, Factual; D030541:Databases, Genetic; D004463:Ecology; D017753:Ecosystem; D019143:Evolution, Molecular; D005828:Genetics, Population; D016678:Genome; D023281:Genomics; D007255:Information Services; D016247:Information Storage and Retrieval; D020407:Internet; D012984:Software