title: [About two cases of massive hypercholesterolemia].
abstract: Two patients presented massive hypercholesterolemia related to acquired disease, intrahepatic cholangitis with cholestasis in one and nephrotic syndrome in the second. Comparison of the lipoprotein patterns demonstrated distinctive pathophysiological processes different from those operating in primary causes of hypercholesterolemia.
authors.affiliation: Laboratoire de biochimie, hôpital Nord, CHU, hôpitaux de Saint-Etienne, Saint-Etienne, France. christian.perier@chu-st-etienne.fr
authors.forename: C
authors.initials: C
authors.lastname: Perier
authors.forename: N
authors.initials: N
authors.lastname: Raby
authors.forename: S
authors.initials: S
authors.lastname: Atieh
authors.forename: R
authors.initials: R
authors.lastname: Granouillet
authors.forename: A
authors.initials: A
authors.lastname: Chamson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016632:Apolipoprotein A-I / Q000097:blood; D001055:Apolipoproteins B / Q000097:blood; D002761:Cholangitis / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D002780:Cholestasis, Intrahepatic / Q000097:blood / Q000150:complications* / Q000209:etiology / Q000378:metabolism; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D007049:Iatrogenic Disease; D017270:Lipoprotein(a) / Q000097:blood; D008297:Male; D009404:Nephrotic Syndrome / Q000097:blood / Q000150:complications* / Q000378:metabolism; D012016:Reference Values; D014280:Triglycerides / Q000097:blood
chemical_list: D016632:Apolipoprotein A-I; D001055:Apolipoproteins B; D008076:Cholesterol, HDL; D017270:Lipoprotein(a); D014280:Triglycerides; D002784:Cholesterol