title: Radical alpha-C-H hydroxyalkylation of ethers and acetal.
abstract: [reaction: see text] Epsilonthers and an acetal were found to undergo direct intermolecular addition to aldehydes under the Et(3)B/air conditions. This study presents a very unique and simple means for the radical alpha-C-H hydroxyalkylation of oxygen-containing compounds.
authors.affiliation: Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan. takey@my-pharm.ac.jp
authors.forename: Takehiko
authors.initials: T
authors.lastname: Yoshimitsu
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Arano
authors.forename: Hiroto
authors.initials: H
authors.lastname: Nagaoka
mesh_terms: D000080:Acetals / Q000138:chemical synthesis*; D000478:Alkylation; D004987:Ethers / Q000138:chemical synthesis*; D005609:Free Radicals / Q000737:chemistry; D008968:Molecular Conformation
chemical_list: D000080:Acetals; D004987:Ethers; D005609:Free Radicals