title: [Evaluation by perfusion-weighted magnetic resonance to hemodynamic character and surgical effect of carotid system stenoses or occlusion].
abstract: OBJECTIVE
  To evaluate hemodynamic character and surgical effect of stenoses or occlusion of carotid artery system by perfusion-weighted MRI.
  
  
  METHODS
  Twenty-one patients with stenoses or occlusion of carotid artery system underwent surgical treatment. Two patients underwent endarterectomy, extracranial-intracranial arterial bypass to 10 patients, and percutaneous stent angioplasty to 9 patients.
  
  
  RESULTS
  Preoperative perfusion-weighted magnetic resonance (MR) revealed normal regional cerebral blood flow in all patients, with delayed time to peak in both middle cerebral artery distribution and border zone. Postoperative perfusion-weighted MR revealed normal time to peak in border zone, but abnormal in middle cerebral artery distribution. Evaluated by perfusion-weighted MR, it showed that surgical method can improve the hemodynamic disorder of this kind of disease. The early curative effect of endarterectomy and percutaneous stent angioplasty is better than extracranial-intracranial arterial bypass.
  
  
  CONCLUSIONS
  Perfusion-weighted MR is a good method to evaluate hemodynamic character of stenoses or occlusion of carotid artery system. Surgical method is helpful to this kind of disease, and its curative effect can be evaluated impersonally and accurately by this new technique.
authors.affiliation: Department of Neurosurgery, Xuanwu Hospital of Capital University of Medical Sciences, Beijing 100053, China. jiaoliqun@163.net
authors.forename: Li-qun
authors.initials: LQ
authors.lastname: Jiao
authors.forename: Feng
authors.initials: F
authors.lastname: Ling
authors.forename: Shen-mao
authors.initials: SM
authors.lastname: Li
authors.forename: Zhong-rong
authors.initials: ZR
authors.lastname: Miao
authors.forename: Xun-ming
authors.initials: XM
authors.lastname: Ji
authors.forename: Feng-shui
authors.initials: FS
authors.lastname: Zhu
authors.forename: Qing-bin
authors.initials: QB
authors.lastname: Song
mesh_terms: D000328:Adult; D000368:Aged; D017130:Angioplasty; D016893:Carotid Stenosis / Q000503:physiopathology / Q000601:surgery; D002560:Cerebrovascular Circulation; D016894:Endarterectomy, Carotid; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D016896:Treatment Outcome