[Vitamin D analogs and calcium metabolism - bone-selective analogs -].
2MD [2-methylene-19-nor- (20S) -1alpha, 25 (OH)(2)D(3)] is a bone-selective vitamin D analog that has been developed on the basis of structure-function study. The bone-selective action of the analog has been tested and confirmed both in vitro and in vivo and its clinical application as a medication for bone diseases is anticipated although its adverse effects remain unclear.
Okano
Toshio
T
Department of Hygienic Sciences, Kobe Pharmaceutical University.