Influence of normovolemic anemia on Doppler characteristics of the abdominal aorta and splanchnic vessels in Beagles.
OBJECTIVE
To ultrasonographically evaluate hemodynamics in the abdominal aorta (AAo) and splanchnic vessels in dogs with experimentally induced normovolemic anemia.


METHODS
11 healthy Beagles.


METHODS
The AAo, cranial mesenteric artery (CMA), celiac artery (CA), hilar splenic artery (HSA), and main portal vein (MPV) were evaluated in conscious dogs immediately before and after experimental induction of severe normovolemic anemia (Hct, 16%) and during recovery from moderate and mild anemia (Hct, 26% and 34%, respectively). Peak systolic velocity (PSV) or peak velocity (PV), time-averaged mean velocity (TAVmean), pulsatility index (PI), resistive index (RI), blood flow, congestion index (CI), and heart rate (HR) were recorded. Results were compared for anemic and control states.


RESULTS
Severe anemia caused significant increases in HR (25% to 70%), PSV (AAo, 45.8%; CMA, 56.1%; and CA, 41.9%), PV (MPV, 84.2%), and TAVmean, (AAo, 69.4%, CMA, 64.3%; CA, 29.7%; and MPV, 76.9%) and significant decreases in PI (AAo, 26.1%; HSA, 19.3%) and Cl (MPV, 45.2%). There was no significant change in PI of the CMA or CA, portal blood flow, or RI of any artery. Significantly higherTAVmean persisted in all vessels during moderate anemia, but higher PSV persisted only in the CMA; PI (CMA and CA) and RI (CA) decreased significantly, but portal blood flow increased significantly. Significant increase in TAVmean (AAo and CMA) persisted during mild anemia, and PI (AAo, CMA, and HSA) and RI (CMA) were significantly lower.


CONCLUSIONS
Doppler ultrasonography revealed hyperdynamic circulation in the AAo and splanchnic vessels in dogs with experimentally induced normovolemic anemia.
Koma
Lee M
LM
Section of Diagnostic Imaging, Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04 Onderstepoort, 0110, Republic of South Africa.
Spotswood
Tim C
TC
Kirberger
Robert M
RM
Becker
Piet J
PJ
D000740:Anemia / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000662:veterinary*; D000818:Animals; D001012:Aorta, Abdominal / Q000000981:diagnostic imaging / Q000502:physiology*; D001783:Blood Flow Velocity; D002445:Celiac Artery / Q000000981:diagnostic imaging / Q000502:physiology; D004195:Disease Models, Animal; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology*; D004285:Dogs; D005260:Female; D006339:Heart Rate / Q000502:physiology; D008297:Male; D008638:Mesenteric Arteries / Q000000981:diagnostic imaging / Q000502:physiology; D011169:Portal Vein / Q000000981:diagnostic imaging / Q000502:physiology; D013152:Splanchnic Circulation / Q000502:physiology*; D018608:Ultrasonography, Doppler / Q000662:veterinary*