title: [Repair of corneal defects using tissue engineering].
abstract: We propose to treat deep corneal burns by grafting a living stromal equivalent, since keratocyte death and stromal destruction are the main factors of ulceration and destruction of the eye. A technique was developed for isolation and grafting a living stromal equivalent. Twenty one patients with deep corneal defects were treated. A stable therapeutic effect was observed in 95% of cases. The advantage of the developed method is partial recovery of affected corneal transparency.
authors.forename: A V
authors.initials: AV
authors.lastname: Vasil'ev
authors.forename: P V
authors.initials: PV
authors.lastname: Makarov
authors.forename: O S
authors.initials: OS
authors.lastname: Rogovaia
authors.forename: R A
authors.initials: RA
authors.lastname: Gundorova
authors.forename: v V
authors.initials: vV
authors.lastname: Terskikh
mesh_terms: D002478:Cells, Cultured; D065306:Corneal Injuries; D005126:Eye Burns / Q000628:therapy*; D005260:Female; D005347:Fibroblasts / Q000637:transplantation*; D006801:Humans; D008297:Male; D012038:Regeneration; D023822:Tissue Engineering / Q000379:methods