Vasodilator activity of the aqueous extract of Viscum album.
The aqueous extract of Viscum album leaves showed a significant coronary vasodilator activity on the Langendorff's isolated and perfused heart model. The data obtained suggest that the aqueous extract of V. album contains some biologically active principles that may act as inducers of the nitric oxide/soluble guanylate cyclase pathway.
Tenorio
F A
FA
Department of Pharmacology, National Institute of Cardiology "Ignacio Chávez", Juan Badiano No. 1, Sección XVI, 14080, Mexico City, Mexico. fatl@att.net.mx
del Valle
L
L
González
A
A
Pastelín
G
G
D000818:Animals; D003326:Coronary Circulation / Q000187:drug effects / Q000502:physiology; D003331:Coronary Vessels / Q000187:drug effects* / Q000502:physiology; D006162:Guanylate Cyclase / Q000378:metabolism; D006168:Guinea Pigs; D006321:Heart / Q000187:drug effects / Q000502:physiology; D008297:Male; D009569:Nitric Oxide / Q000378:metabolism; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D028182:Viscum album
D010936:Plant Extracts; D014665:Vasodilator Agents; D009569:Nitric Oxide; D006162:Guanylate Cyclase