Tc-99m MDP bone scintigraphy of myositis as a manifestation of chronic graft-versus-host disease after non-myeloablative peripheral stem cell transplantation.
A 27-year-old man developed polymyositis as a manifestation of chronic graft-versus-host disease (GVHD) after non-myeloablative peripheral blood stem cell transplantation (PBSCT). Bone scintigraphy showed intense, striped, and heterogeneous accumulation of Tc-99m methylene diphosphonate (MDP) in the soft-tissue of his lower limbs, while faint activities were seen in the right upper limb. Tc-99m MDP scintigraphy was very useful for accurate and objective evaluation of the severity of the muscle injury and the extent of polymyositis caused by chronic GVHD.
Mitomo
Maki
M
Department of Medical Imaging, Sapporo City General Hospital, Japan.
Miyazaki
Chihoko
C
Mukai
Masaya
M
Usami
Yohko
Y
Nagano
Shunsuke
S
Nakamura
Noriko
N
Kubo
Kohzoh
K
D000328:Adult; D001842:Bone and Bones / Q000000981:diagnostic imaging; D005121:Extremities / Q000000981:diagnostic imaging; D006086:Graft vs Host Disease / Q000150:complications* / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D009220:Myositis / Q000000981:diagnostic imaging* / Q000209:etiology*; D036102:Peripheral Blood Stem Cell Transplantation / Q000009:adverse effects*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate
D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate