Physical determinants of systolic murmur intensity in aortic stenosis.
We investigated which physical parameter has the greatest impact on the perceived loudness of a systolic murmur in aortic stenosis. Loudness of murmur in aortic stenosis correlated best with peak momentum transfer--and thus with body size--so that loud murmurs predict severe disease less reliably in larger patients.
Kuperstein
Rafael
R
Heart Institute, Sheba Medical Center, Tel Hashomer, Israel. grafikup@netvision.net.il
Feinberg
Micha S
MS
Eldar
Michael
M
Schwammenthal
Ehud
E
D000368:Aged; D000369:Aged, 80 and over; D001011:Aorta / Q000503:physiopathology; D001022:Aortic Valve Insufficiency / Q000175:diagnosis / Q000503:physiopathology; D001024:Aortic Valve Stenosis / Q000175:diagnosis / Q000503:physiopathology*; D049628:Body Size; D005260:Female; D006326:Heart Auscultation; D006337:Heart Murmurs; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009131:Muscle, Smooth, Vascular / Q000503:physiopathology; D013018:Sound Spectrography; D013599:Systole / Q000502:physiology*; D014732:Vibration