[Comparative research on attenuation characteristics of human bladder cancer tissue at different wavelengths of laser and their linearly polarized laser in vitro].
In this paper, a double-integrating-spheres system, the basic principle of measuring technology of ray radiation, and the optical model of biological tissues were used for the study. Attenuation characteristics of human bladder cancer tissue at 467.5, 488, 496.5, 514.5 and 532 nm laser and their linearly polarized laser irradiation were studied. The results of measurement showed that the attenuation characteristics of human bladder cancer tissue in Kubelka-Munk two-flux model were different at different wavelengths of laser irradiation in the range of five different laser wavelengths. There were significant differences in the total attenuation or effective attenuation coefficients of human bladder cancer tissue at 476.5, 496.5, and 532 nm wavelengths of laser and their linearly polarized laser irradiation (P>0.05), and there were no significant differences at 488 and 514.5 nm wavelengths of laser and their linearly polarized laser irradiation in two-flux model (P>0.05). The total attenuation and effective attenuation coefficients of human bladder cancer tissue at 532 nm laser and its linearly polarized laser irradiation were obviously bigger than those at other four different wavelengths of laser and their linearly polarized laser irradiation in two-flux model. The total attenuation and effective attenuation coefficients of human bladder cancer tissue at five different wavelengths of laser and their linearly polarized laser irradiation increased with the decrease of these wavelengths, there were significant differences in those at 476.5, 496.5 and 514.5 nm wavelengths of laser and their linearly polarized laser irradiation (P<0.05), and there were no significant differences in those at 488 and 532 nm wavelengths of laser and their linearly polarized laser irradiation in light transport theory (P>0.05).
Wei
Hua-jiang
HJ
Institute of Laser Life Science, South China Normal University, Guangzhou 510631, China.
Xing
Da
D
Wu
Guo-yong
GY
Jin
Ying
Y
Gu
Huai-min
HM
D002460:Cell Line; D006801:Humans; D007834:Lasers / Q000145:classification; D008027:Light; D055095:Optics and Photonics; D012542:Scattering, Radiation; D013055:Spectrophotometry, Infrared / Q000379:methods; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000473:pathology