Late anthracyclines cardiotoxicity associated with infection by Mycoplasma pneumoniae. A case report.
We report the case of a 15-year-old male developing progressive myocardiopathy secondary to late anthracycline cardiotoxicity. At 2 years of age, the patient received chemotherapy with anthracyclines (adriamycin) at an accumulated dose of 510 mg/m2 due to the presence of non-Hodgkin lymphoma which subsided completely and he has been asymptomatic since then. A number of recurrent respiratory infections occurred as triggering factors of the condition, and the laboratory tests evidenced positive serology for Mycoplasma pneumoniae suggesting a recent contact.
Valencia
José
J
Martínez
Juan Gabriel
JG
Sogorb
Francisco
F
Niveiro
María
M
D000293:Adolescent; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects*; D000907:Antibodies, Bacterial / Q000276:immunology; D009202:Cardiomyopathies / Q000139:chemically induced*; D004317:Doxorubicin / Q000009:adverse effects*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000188:drug therapy; D008297:Male; D009177:Mycoplasma pneumoniae / Q000276:immunology; D011019:Pneumonia, Mycoplasma / Q000150:complications* / Q000382:microbiology
D000903:Antibiotics, Antineoplastic; D000907:Antibodies, Bacterial; D004317:Doxorubicin