title: [Correlation of age and sex hormones to the transition zone volume of the prostate].
abstract: OBJECTIVE
  To investigate the correlation of age and sex hormones to the total volume (TV) and transition zone volume
  
  
  METHODS
  Eighty-two men were divided into two groups with the age of 60 as the dividing line. Prostatic TV (TZV and TZV were measured with transrectal ultrasound (TRUS) and the concentrations of total testosterone (T), free testosterone (fT) and estradiol (E2) were measured with radioimmunoassay. Exponential curve regression and one-factor analysis of variance (ANOVA) were used for statistical analysis.
  
  
  RESULTS
  Age was significantly correlated with TV, TZV and the TZV/TV ratio, P < 0.01. There was a significant positive correlation between the concentrations of fT and TZV, a negative correlation between those of E2 and TZV (P < 0.01), but no correlation between those of T and TZV (P > 0.05).
  
  
  CONCLUSIONS
  The significant acceleration of the TZV of the prostate after the age of 60 is related to sex hormones.
authors.affiliation: Department of Urology, Ninth People's Hospital Affiliated to Shanghai Second Medical University, Shanghai 200011, China. xmx197630@163.com
authors.forename: Ming-Xi
authors.initials: MX
authors.lastname: Xu
authors.forename: Jun
authors.initials: J
authors.lastname: Ying
authors.forename: De-Hong
authors.initials: DH
authors.lastname: Yao
authors.forename: Yue-Qing
authors.initials: YQ
authors.lastname: Jiang
authors.forename: Zhi-Kang
authors.initials: ZK
authors.lastname: Cai
authors.forename: Xiao-Min
authors.initials: XM
authors.lastname: Ren
authors.forename: Lin-Guo
authors.initials: LG
authors.lastname: Lu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D000704:Analysis of Variance; D004958:Estradiol / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000000981:diagnostic imaging*; D012044:Regression Analysis; D013739:Testosterone / Q000097:blood*; D014463:Ultrasonography
chemical_list: D013739:Testosterone; D004958:Estradiol