[Correlation of age and sex hormones to the transition zone volume of the prostate].
OBJECTIVE
To investigate the correlation of age and sex hormones to the total volume (TV) and transition zone volume


METHODS
Eighty-two men were divided into two groups with the age of 60 as the dividing line. Prostatic TV (TZV and TZV were measured with transrectal ultrasound (TRUS) and the concentrations of total testosterone (T), free testosterone (fT) and estradiol (E2) were measured with radioimmunoassay. Exponential curve regression and one-factor analysis of variance (ANOVA) were used for statistical analysis.


RESULTS
Age was significantly correlated with TV, TZV and the TZV/TV ratio, P < 0.01. There was a significant positive correlation between the concentrations of fT and TZV, a negative correlation between those of E2 and TZV (P < 0.01), but no correlation between those of T and TZV (P > 0.05).


CONCLUSIONS
The significant acceleration of the TZV of the prostate after the age of 60 is related to sex hormones.
Xu
Ming-Xi
MX
Department of Urology, Ninth People's Hospital Affiliated to Shanghai Second Medical University, Shanghai 200011, China. xmx197630@163.com
Ying
Jun
J
Yao
De-Hong
DH
Jiang
Yue-Qing
YQ
Cai
Zhi-Kang
ZK
Ren
Xiao-Min
XM
Lu
Lin-Guo
LG
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D000704:Analysis of Variance; D004958:Estradiol / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000000981:diagnostic imaging*; D012044:Regression Analysis; D013739:Testosterone / Q000097:blood*; D014463:Ultrasonography
D013739:Testosterone; D004958:Estradiol