The familial clustering of renal disease and related phenotypes.
This article reviews the familial aggregation of chronic kidney diseases including end-stage renal disease and albuminuria, along with variation in glomerular filtration rate. In addition to environmental influences on the progression of nephropathy, epidemiologic evidence in support of the existence of renal failure susceptibility genes is presented.
Satko
Scott G
SG
Section on Nephrology, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1053, USA. ssatko@wfubmc.edu
Freedman
Barry I
BI
D015415:Biomarkers; D018450:Disease Progression; D020022:Genetic Predisposition to Disease / Q000208:ethnology / Q000235:genetics; D006801:Humans; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000208:ethnology* / Q000235:genetics*; D008403:Mass Screening; D010641:Phenotype
D015415:Biomarkers