Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome.
Probiotic agents are increasingly used for the treatment and prevention of a variety of infectious and inflammatory conditions. They are generally safe, but complications of probiotic use can occur. In this report, we describe bacteremia after ingestion of a Lactobacillus rhamnosus GG probiotic tablet in a child with short gut syndrome. We used sequencing of the ribosomal operon region and strain typing with pulsed field electrophoresis of the isolates to show identity between the tablet and bloodstream isolates.
De Groote
Mary Ann
MA
University of Colorado Health Sciences Center, Denver, CO, USA.
Frank
Daniel N
DN
Dowell
Elaine
E
Glode
Mary P
MP
Pace
Norman R
NR
D000900:Anti-Bacterial Agents; D016470:Bacteremia / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D001483:Base Sequence; D002404:Catheterization / Q000009:adverse effects / Q000379:methods; D003131:Combined Modality Therapy; D004269:DNA, Bacterial / Q000032:analysis; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005500:Follow-Up Studies; D005774:Gastrostomy / Q000009:adverse effects / Q000379:methods; D016908:Gram-Positive Bacterial Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D007778:Lactobacillus / Q000145:classification*; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000379:methods; D019936:Probiotics / Q000008:administration & dosage*; D018570:Risk Assessment; D012720:Severity of Illness Index; D012778:Short Bowel Syndrome / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial