[Hormone replacement therapy and vascular function].
Hormone replacement therapy (HRT) by estrogen has a cardioprotective effect in postmenopausal women. This effect results partly from the direct actions of estrogen on vascular receptors. These are mainly endothelium-dependent or endothelium-independent vascular relaxing effects. Increases in prostacyclin and bradykinin, and a decrease in endothelin-1 by estrogen are involved.
Sumino
H
H
Second Department of Internal Medicine, Gunma University School of Medicine.
Kurabayashi
M
M
Ichikawa
S
S