title: Follow-up of testicular microlithiasis for subsequent testicular cancer development.
abstract: BACKGROUND
  To demonstrate the relationship between testicular microlithiasis and testicular tumor development.
  
  
  METHODS
  Between January 1996 and March 2004, bilateral testicular microlithiasis was found in 40 of the 5,263 patients who underwent scrotal ultrasonography yielding a prevalence of 0.76%. Of the 40 patients, 4 patients with concomitant testicular tumors were excluded from the study. The remaining 36 patients were enrolled into the study and followed by ultrasonography at 6-month intervals.
  
  
  RESULTS
  Patient ages ranged between 1 and 69 years (mean 31 +/- 14 years). The median ultrasonography follow-up was 34 months (range, 1-96). Testicular tumor development was not observed in any of these 36 patients during the follow-up period.
  
  
  CONCLUSIONS
  Extensive evaluation including computerized tomography, testicular tumor markers and testicular biopsy of patients with testicular microlithiasis is unnecessary and also increases patient anxiety. Yet annual ultrasonography and physical examination should be performed if ever until testicular microlithiasis is completely accepted as a nonpremalignant disease.
authors.affiliation: Department of Radiology, Baskent University Faculty of Medicine, Adana Teaching and Medical Research Center, R-01250 Adana, Turkey.
authors.forename: Mir Ali
authors.initials: MA
authors.lastname: Pourbagher
authors.forename: Ferhat
authors.initials: F
authors.lastname: Kilinc
authors.forename: Sezgin
authors.initials: S
authors.lastname: Guvel
authors.forename: Aysin
authors.initials: A
authors.lastname: Pourbagher
authors.forename: Tulga
authors.initials: T
authors.lastname: Egilmez
authors.forename: Hakan
authors.initials: H
authors.lastname: Ozkardes
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002137:Calculi / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013733:Testicular Diseases / Q000150:complications*; D013736:Testicular Neoplasms / Q000209:etiology*