[Determination of Levofloxacin by chemiluminescence method].
A novel chemiluminescence method for the determination of Levofloxacin is based on its enhancement effect on thereaction of luminol with H2O2. The calibration graph is linear over the range of 5.53 x 10(-11)-2.21 x 10(-8) mol x L(-1) and the detection limit is 1.38 x 10(-11) mol x L(-1). The relative standard deviation (RSD) is 2.56% (n = 9). The method has been successfully applied to the determination of Levofloxacin in capsule samples.
Liu
Er-bao
EB
College of Chemistry and Material Science, Shanxi Normal University, Linfen 041004, China.
Wei
Hong-qing
HQ
Han
Su-qin
SQ
Ren
Rong-fang
RF
Zhao
Shen-yan
SY
Kang
Jian-ping
JP
D002138:Calibration; D017022:Flow Injection Analysis; D006861:Hydrogen Peroxide / Q000737:chemistry; D064704:Levofloxacin; D057230:Limit of Detection; D049449:Luminescence; D008163:Luminescent Measurements / Q000379:methods*; D008165:Luminol / Q000737:chemistry*; D015242:Ofloxacin / Q000032:analysis*; D004364:Pharmaceutical Preparations / Q000032:analysis*
D004364:Pharmaceutical Preparations; D008165:Luminol; D064704:Levofloxacin; D015242:Ofloxacin; D006861:Hydrogen Peroxide