title: Strategies to retard the progression of chronic kidney disease.
abstract: Chronic kidney disease (CKD) is a common and, in advanced cases, highly morbid disorder. The most severe form of CKD is end-stage renal disease (ESRD), in which the patient requires some form of renal replacement therapy to survive. The increasing incidence, prevalence, and costs of ESRD are major national health care concerns; interventions that may prevent or slow the progression of CKD towards ESRD are extremely important and the focus of this article.
authors.affiliation: Renal Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
authors.forename: Kambiz
authors.initials: K
authors.lastname: Zandi-Nejad
authors.forename: Barry M
authors.initials: BM
authors.lastname: Brenner
mesh_terms: D000740:Anemia / Q000150:complications; D018450:Disease Progression; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications; D006973:Hypertension / Q000150:complications; D007676:Kidney Failure, Chronic / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy*; D009765:Obesity / Q000150:complications; D011507:Proteinuria / Q000209:etiology; D012907:Smoking / Q000009:adverse effects; D016540:Smoking Cessation