Hydrogen-bonding and C-H...pi interactions in 7-hydroxy-3-methoxy-4-methyl-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidin-1(9H)-one.
In the title compound, C10H14N2O3, a pyrimidine ring is fused with a piperidine ring. The pyrimidine ring is planar, whereas the piperidine ring adopts a half-chair conformation. The molecules of the title compound are connected via O-H...O intermolecular hydrogen bonds into infinite zigzag chains. The pyrimidine ring is involved in three C-H...pi interactions, which link the hydrogen-bonded chains into a three-dimensional framework.
Cetina
Mario
M
Faculty of Textile Technology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, Croatia. mcetina@ttf.hr
Nagl
Ante
A
Prekupec
Svjetlana
S
Raić-Malić
Silvana
S
Mintas
Mladen
M
D000970:Antineoplastic Agents / Q000737:chemistry; D000998:Antiviral Agents / Q000737:chemistry; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D015394:Molecular Structure; D010880:Piperidines / Q000737:chemistry*; D011744:Pyrimidinones / Q000737:chemistry*
D000970:Antineoplastic Agents; D000998:Antiviral Agents; D010880:Piperidines; D011744:Pyrimidinones