title: Liver transplantation as definitive treatment for a factor V Leiden mutation.
abstract: Liver transplantation (LT) was achieved for factor V Leiden-induced thrombophilia in a neonate with hepatic veno-occlusive disease. Initial LT was performed with a liver segment removed from a child with primary oxalosis. Four months later, a second, definitive LT was performed. The child remains well without recurrent thrombosis.
authors.affiliation: Division of Solid Organ Transplantation, Nemours Biomedical Research, Nemours Children's Clinic-Wilmington, Alfred I. duPont Hospital for Children, Delaware, USA.
authors.forename: Stephen P
authors.initials: SP
authors.lastname: Dunn
authors.forename: Anthony
authors.initials: A
authors.lastname: Tsai
authors.forename: Gregory
authors.initials: G
authors.lastname: Griffin
authors.forename: Stephen
authors.initials: S
authors.lastname: Toth
authors.forename: Adela T
authors.initials: AT
authors.lastname: Casas-Melley
authors.forename: Kathleen P
authors.initials: KP
authors.lastname: Falkenstein
authors.forename: Cindy A
authors.initials: CA
authors.lastname: Marando
authors.forename: Leslie J
authors.initials: LJ
authors.lastname: Krueger
mesh_terms: D005165:Factor V / Q000235:genetics*; D006504:Hepatic Veno-Occlusive Disease / Q000235:genetics / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D017093:Liver Failure / Q000235:genetics / Q000601:surgery; D016031:Liver Transplantation; D008297:Male; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA / Q000379:methods; D019851:Thrombophilia / Q000235:genetics / Q000601:surgery*
chemical_list: C095381:factor V Leiden; D005165:Factor V