[Clinicopathologic analysis of primary pure squamous cell carcinoma of the breast].
OBJECTIVE
To analyze the clinicopathologic characteristics and treatment method for primary pure squamous cell carcinoma of the breast.


METHODS
Twelve patients with primary squamous cell carcinoma of the breast pathologically confirmed were retrospectively reviewed. The clinical characteristics, diagnosis, treatment and prognosis were analyzed.


RESULTS
All 12 patients were women with median age of 50 years (44-76 years). The patients all presented a single mass in the breast on presentation. The diameter ranged from 2.5 cm to 10.0 cm in diameter. All of the patients had undergone surgical resection. There were 6 cases in stage IIa, 2 in IIb, 2 in IIIa and 2 in IIIb according to the TNM staging system of AJCC and UICC. Ten of the 12 cases were followed-up from 4 months to 189 months.


CONCLUSIONS
Primary squamous cell carcinoma of the breast is often in need of diagnosis by exclusion, but can be initially confirmed by fine needle aspiration. Presently, no standard therapy can be recommended in practice. The prognosis is controversial.
Hu
Wei-guo
WG
Department of General Surgical Oncology, Cancer Institute (Hospital), Peking Union Medical College, Beijing 100021, China.
Zhang
Bao-ning
BN
Xuan
Li-xue
LX
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008408:Mastectomy / Q000379:methods; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies