[Risk factors of complications (bleedings) in duodenal ulcer disease].
The role of ulceration risk factors in the development of duodenal ulcer complications was under examination. The leading role of risk factors for the development of complications in case of an infection of the stomach mucous coat with virulent VacA-positive strains of Helicobacter pylori belonging to the s1/s2 subtype and characterized by a high amount of mixed genotypes of the VacA gene (64%)--was established. The proved growth of immunological inflammation markers and depression of the humoral immunity part was discovered.
Sarsenbaeva
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D000328:Adult; D000917:Antibody Formation; D004381:Duodenal Ulcer / Q000150:complications* / Q000276:immunology / Q000382:microbiology; D006471:Gastrointestinal Hemorrhage / Q000209:etiology* / Q000382:microbiology; D005838:Genotype; D016481:Helicobacter Infections / Q000150:complications* / Q000276:immunology; D016480:Helicobacter pylori / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D008875:Middle Aged; D012307:Risk Factors