Cutaneous hyperpigmentation due to chronic quinine ingestion.
Striking hyperpigmentation developed on the arms of a 66-year-old man following protracted oral ingestion of quinine. Although this phenomenon is well described in conjunction with other similar drugs, including quinidine, it has not been well documented following exposure to quinine. This adverse event is cosmetic in nature and is not associated with functional impairment.
Rosen
Ted
T
Department of Dermatology, Baylor College of Medicine and Veterans Administration Medical Center, Houston, Texas, USA. tedrosenmd@aol.com
Aponte
Carol
C
D000368:Aged; D004305:Dose-Response Relationship, Drug; D005500:Follow-Up Studies; D006801:Humans; D017495:Hyperpigmentation / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D011803:Quinine / Q000009:adverse effects* / Q000627:therapeutic use; D018570:Risk Assessment; D012720:Severity of Illness Index; D013997:Time Factors; D034941:Upper Extremity
D011803:Quinine