title: Clerodane diterpenoids from Pulicaria wightiana.
abstract: Five clerodane diterpenoids have been isolated from the aerial parts of Pulicaria wightiana along with 3'5,6-trihydroxy-3,4',7-trimethoxyflavone and 2-methyl-5-hydroxy-chroman-4-one. The structures and stereochemistry of the compounds were established from spectral (mainly 1D and 2D NMR) studies. The last two compounds were not reported earlier from this plant. The antibacterial activity of the diterpenoids were studied.
authors.affiliation: Indian Institute of Chemical Technology, Organic Chemistry-1, Tarnaka, Hyderabad 500 007, India. biswanthdas@yahoo.com
authors.forename: Biswanath
authors.initials: B
authors.lastname: Das
authors.forename: M
authors.initials: M
authors.lastname: Ravinder Reddy
authors.forename: R
authors.initials: R
authors.lastname: Ramu
authors.forename: N
authors.initials: N
authors.lastname: Ravindranath
authors.forename: H
authors.initials: H
authors.lastname: Harish
authors.forename: K V S
authors.initials: KV
authors.lastname: Ramakrishna
authors.forename: Y
authors.initials: Y
authors.lastname: Koteswar Rao
authors.forename: K
authors.initials: K
authors.lastname: Harakishore
authors.forename: U S N
authors.initials: US
authors.lastname: Murthy
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D019659:Asteraceae / Q000737:chemistry*; D001419:Bacteria / Q000187:drug effects; D002839:Chromans / Q000302:isolation & purification; D045785:Diterpenes, Clerodane / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D047309:Flavones / Q000302:isolation & purification; D015394:Molecular Structure
chemical_list: C501184:2-methyl-5-hydroxy-chroman-4-one; C501183:3',5,6-trihydroxy-3,4',7-trimethoxyflavone; D000900:Anti-Bacterial Agents; D002839:Chromans; D045785:Diterpenes, Clerodane; D047309:Flavones