[Molecular genetic characterization of rabies virus, isolated in Western Siberia].
The paper covers a study of four rabies viruses, isolated in 2003 from man, wild foxes, badgers and home cats inhabiting entirely different districts of Novosibirsk suburb, and a sample taken from a bat from Maslaninsky district. The samples were studied by fluorescent antibody microscopy and a biological test on white mice, RT-PCR-analysis of NP-genes and sequencing. The study revealed that related variants of rabies viruses circulated in Novosibirsk region, and those formed two groups in genotype 1. Most of the amino acid replacements found in the study are only characteristic of the viruses circulating in the given territory.
Zaĭkovskaia
A V
AV
Ternovo
V A
VA
Aksenov
V I
VI
Rassadkin
Iu N
IuN
Shestopalov
A M
AM
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology; D002415:Cats; D002685:Chiroptera / Q000821:virology; D019353:Endemic Diseases; D005589:Foxes / Q000821:virology; D005838:Genotype; D006801:Humans; D008297:Male; D051379:Mice; D008856:Microscopy, Fluorescence; D045969:Mustelidae / Q000821:virology; D016133:Polymerase Chain Reaction; D012367:RNA, Viral / Q000235:genetics*; D011818:Rabies / Q000453:epidemiology* / Q000821:virology; D012209:Rhabdoviridae / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification; D012800:Siberia / Q000453:epidemiology
D000914:Antibodies, Viral; D012367:RNA, Viral