title: Addition of rhythm to non-pulsatile circulation.
abstract: The development of a rotary blood pump (RP) is desirable as it can be used as a small ventricular assistance device (VAD). However, a RP does not generate any pulse. It may be physiologically better for the patient if the RP could generate a pulse. We have attempted to develop a device that produces a pulse in the RP. Intra-aortic balloon pumping (IABP) is effective in producing a pulse. However, the IABP cannot be implanted inside the body. Therefore, an attempt was made to develop pulse-generating equipment that was not driven by air pressure. The ball screw motor was considered as a possible candidate. In the future, we plan to apply small shape memory alloys. An electrohydraulic system was adopted, and actuator power output was connected to the diaphragm. The diaphragm was placed outside the ventricle. Most RPs developed throughout the world drain blood from the ventricle. The pulse wave should be generated if a pulse is added by the part from which blood is being drawn. In this study, animal experiments were conducted and the output assistance was tested from outside the ventricle. The device operated effectively in the animal experiment. The RP can easily be equipped with this device at the time of performing the implant operation. For a patient with problems of peripheral circulation and the internal organ function, it may prove to be an effective device.
authors.affiliation: Department of Medical Engineering and Cardiology, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryo-maci, Aoba-ku, Sendai 980-77, Japan. yambe@idac.tohoku.ac.jp
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Yambe
authors.forename: Kazumitsu
authors.initials: K
authors.lastname: Sekine
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Shiraishi
authors.forename: Makoto
authors.initials: M
authors.lastname: Watanabe
authors.forename: Mune-ichi
authors.initials: M
authors.lastname: Shibata
authors.forename: Tasuku
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: Wang
authors.initials: W
authors.lastname: Quintian
authors.forename: Xudong
authors.initials: X
authors.lastname: Duan
authors.forename: Liu Hong
authors.initials: LH
authors.lastname: Jian
authors.forename: Makoto
authors.initials: M
authors.lastname: Yoshizawa
authors.forename: Akira
authors.initials: A
authors.lastname: Tanaka
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Matsuki
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Sato
authors.forename: You-ichi
authors.initials: Y
authors.lastname: Haga
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Esashi
authors.forename: Kouichi
authors.initials: K
authors.lastname: Tabayashi
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Mitamura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sasada
authors.forename: Eimei
authors.initials: E
authors.lastname: Sato
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Saijo
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Nitta
mesh_terms: D032761:Animal Experimentation; D000818:Animals; D004867:Equipment Design / Q000379:methods; D006041:Goats; D006353:Heart-Assist Devices / Q000639:trends; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D007564:Japan; D009102:Multiple Organ Failure / Q000628:therapy; D011673:Pulsatile Flow / Q000502:physiology*; D013008:Somatotypes / Q000502:physiology