[Adhesion dependence of coagulase-negative staphylococci to biomaterials and PIA polysaccharide synthesis on icaADBC operon presence].
Both Staphylococcus epidermidis and Staphylococcus haemolyticus are important causes of infections associated with catheters and other medical devices. This infections result in significant morbidity, mortality and economic cost. It has recently been shown that not only S. epidermidis but also S. haemolyticus can produce slime and carries the ica operon responsible for and slime production. In the operon, coexpression of icaA and icaD is required for full slime synthesis. This study is focused on detecting icaA and icaD genes in S. haemolyticus and comparison of these two species. It turned out that strain representatives within the same species behave very differently and a single tested strain from each species is unlikely to be representative of the species as a whole. Contrary to S. epidermidis, S. haemolyticus strain appeared to carry no icaA-like and icaD-like genes, but was able to form biofilm in vitro.
Bartoszewicz
Marzenna
M
Zakład Mikrobiologii Akademii Medycznej we Wrocławiu.
Nowicka
Joanna
J
Janikowska
Ewa
E
Przondo-Mordarska
Anna
A
D018441:Biofilms; D002404:Catheterization; D006801:Humans; D009876:Operon; D016133:Polymerase Chain Reaction; D011135:Polysaccharides, Bacterial / Q000235:genetics*; D013212:Staphylococcus epidermidis / Q000235:genetics*; D041162:Staphylococcus haemolyticus / Q000235:genetics*
D011135:Polysaccharides, Bacterial; C113579:polysaccharide intercellular adhesin