title: [Seronegative spondyloarthropathies--pathogenesis, diagnosis, treatment-].
abstract: Seronegative spondyloarthropathies (SNSA) include a group of diseases with arthritis that are negative for rheumatoid factor. The borders of the disease are sometimes obscure, and SNSA has its own classification criteria. The investigation on the speciality of HLA-B27 will be important for the understanding of SNSA pathogenesis. Several reports shows that anti-TNF-alpha therapy is powerful measure for the management of SNSA.
authors.affiliation: Department of Allergy and Rheumatology, University of Tokyo.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Yamaguchi