[The applications of SERS to labeled immunoassay].
Combining the high sensitivity of a variety of readout technologies with the specific adsorption between antibody and antigen, labeled immunoassay possesses a remarkable effect in microanalysis. The discovery and confirmation of Surface enhanced Raman Spectroscopy (SERS) made Raman spectroscopy a powerful tool in many research fields, especially in biomedicine. In this report, the authors describe the applications of the high sensitivity of SERS to labeled immunoassay, and introduce some work in this field by our laboratory.
Qiu
Li-qun
LQ
Department of Chemistry, Suzhou University, Suzhou 215006, China.
Gu
Ren-ao
RA
D000327:Adsorption; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000941:Antigens / Q000276:immunology*; D015374:Biosensing Techniques; D004563:Electrochemistry / Q000379:methods; D007118:Immunoassay / Q000379:methods*; D007074:Immunoglobulin G / Q000276:immunology*; D053768:Metal Nanoparticles / Q000737:chemistry; D046210:Microfluidic Analytical Techniques; D008855:Microscopy, Electron, Scanning; D036103:Nanotechnology / Q000379:methods; D013059:Spectrum Analysis, Raman / Q000379:methods*; D020349:Surface Plasmon Resonance / Q000379:methods; D013499:Surface Properties
D000911:Antibodies, Monoclonal; D000941:Antigens; D007074:Immunoglobulin G