[The mechanism of osteoprosis revealed by the animal studies: the involvement of alveolar bone resorption induced by the periodontal disease].
The experimental model of ovariectomy (OVX) has been well used as a model for studying the pathogenesis of postmenopausal osteoporosis. It is known that the hematopoietic environment in the bone marrow is altered leading to the up-regulation of osteoclastogenesis after the estrogen withdrawal. We discuss the possibility whether this alternation of lymphocyte-lineage cells could trigger off a risk factor for the periodontal disease.
Aoki
Kazuhiro
K
Section of Pharmacology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University.
Ohya
Keiichi
K