title: Once-daily aminoglycoside administration.
abstract: Once-daily aminoglycoside dosing is effective in treating gram-negative infections, including those associated with bones and joints.
authors.affiliation: University of Kentucky Chandler Medical Center Lexington, Ky, USA.
authors.forename: Trenika
authors.initials: T
authors.lastname: Mitchell
authors.forename: Kazumi
authors.initials: K
authors.lastname: Morita
authors.forename: Kelly M
authors.initials: KM
authors.lastname: Smith
mesh_terms: D000617:Aminoglycosides / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy*; D003404:Creatinine / Q000097:blood; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004352:Drug Resistance, Microbial; D006319:Hearing Loss, Sensorineural / Q000139:chemically induced; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced; D010000:Osteitis / Q000188:drug therapy; D013997:Time Factors
chemical_list: D000617:Aminoglycosides; D003404:Creatinine