title: Laparoscopic radiofrequency thermal ablation: a new approach to symptomatic uterine myomas.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the feasibility and efficacy of laparoscopic radiofrequency ablation of uterine fibroids.
  
  
  METHODS
  Eighteen women with symptomatic intramural uterine myomas underwent radiofrequency ablation under laparoscopic guidance. Postoperative sonographic evaluations of the fibroids size were scheduled at 1, 3, 6 ,9, and 12 months. The impact of myoma-related symptoms on quality of life (QOL) was assessed using a validated questionnaire.
  
  
  RESULTS
  The median number of myomas treated per patient was 1 (1-3). The median baseline volume of the dominant myoma was 67.2 cm 3 (14.8-332.8). No intraoperative or postoperative complications occurred. The median reductions in myomas volume were 41.5%, 59%, and 77% at 1, 3, and 6-months, follow-up evaluation, respectively. No further change in fibroid size was observed at 9 months and 1 year. A significant improvement in the symptoms score and QOL score was observed at 3 and 6 months, follow-up.
  
  
  CONCLUSIONS
  In this pilot study, laparoscopic radiofrequency ablation successfully reduced fibroid symptoms and fibroid volume in short-term follow-up. Additional studies are needed before its efficacy and safety can be confirmed.
authors.affiliation: Department of Obstetrics and Gynecology, University of Verona, Italy.
authors.forename: Valentino
authors.initials: V
authors.lastname: Bergamini
authors.forename: Fabio
authors.initials: F
authors.lastname: Ghezzi
authors.forename: Antonella
authors.initials: A
authors.lastname: Cromi
authors.forename: Gaia
authors.initials: G
authors.lastname: Bellini
authors.forename: Giovanni
authors.initials: G
authors.lastname: Zanconato
authors.forename: Stefano
authors.initials: S
authors.lastname: Scarperi
authors.forename: Massimo
authors.initials: M
authors.lastname: Franchi
mesh_terms: D017115:Catheter Ablation / Q000295:instrumentation / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015907:Hysteroscopy; D007889:Leiomyoma / Q000601:surgery*; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000601:surgery*