title: [The study on pathogenesis of latex allergy.].
abstract: OBJECTIVE
  In order to study the pathogenesis of latex allergy and the significance in the prevention and cure of occupational diseases.
  
  
  METHODS
  651 cases in the out-patient department were tested with skin prick test (SPT), and the specific IgE (sIgE) to latex were detected by means of disk ELISA and Western-blot.
  
  
  RESULTS
  It was found that the positive rate of latex SPT (37.5%) and sIgE (31.25%) were rather higher in patients in comparison with those of the normal. The positive rate of latex sIgE was much higher in the high-risk group than that of the low-risk group and the normal. The serum of the patients can react with multi-bands in the latex glove extracts.
  
  
  CONCLUSIONS
  The prevalence of latex allergy is rather high, this disease is mediated by IgE. The people in high-risk should be tested by latex allergy in order to take proper occupational and daily protection.
authors.affiliation: The Department of Immunology and Rheumatology, Qingdao Municipal Hospital, Qingdao 266011, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Li
authors.forename: Bo
authors.initials: B
authors.lastname: Cehn
authors.forename: Yi-ping
authors.initials: YP
authors.lastname: Xu
authors.forename: Jian-hua
authors.initials: JH
authors.lastname: Wang
authors.forename: Zu-qun
authors.initials: ZQ
authors.lastname: Wu
authors.forename: Han-bing
authors.initials: HB
authors.lastname: Zou
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007223:Infant; D020315:Latex Hypersensitivity / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control; D010045:Outpatients; D012882:Skin Tests; D055815:Young Adult
chemical_list: D007073:Immunoglobulin E