title: [Clinical observation of the lead discharging effect of paiqian chewing tablet].
abstract: OBJECTIVE
  To observe the effect of paiqian chewing tablet (PQCT) on lead discharging and health in children.
  
  
  METHODS
  Adopting self-control and inter-group control method, 94 children with blood lead level exceeding 100 microg/L were randomly divided into the observed group and the control group. The observation period for both groups was 30 days.
  
  
  RESULTS
  At the 20th and 30th day of treatment, the urinary lead output in the observed group was significantly higher than that in the control group (P < 0.05, P < 0.01), and showed significant difference as compared with that before treatment (P < 0.05). Besides, the total amount of urinary lead discharging in the observed group was significantly more than that in the control group (P < 0.05).
  
  
  CONCLUSIONS
  PQCT has markedly lead discharging improvement action with no influence on urinary calcium and zinc excretion. As all the routine indexes of blood and urine ranged within the normal extent, it demonstrated that PQCT was harmless to the health of observed individual.
authors.affiliation: Center of Technology, Jiangzhong Pharmaceutical Co. Ltd., Nanchang 330077.
authors.forename: Jian-zhong
authors.initials: JZ
authors.lastname: Lu
authors.forename: Yu
authors.initials: Y
authors.lastname: Cai
authors.forename: Yi-bin
authors.initials: YB
authors.lastname: Lu
authors.forename: Ping
authors.initials: P
authors.lastname: Yu
authors.forename: Mei-xiang
authors.initials: MX
authors.lastname: Rao
authors.forename: Hui
authors.initials: H
authors.lastname: Zou
mesh_terms: D002648:Child; D004311:Double-Blind Method; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007854:Lead / Q000097:blood / Q000652:urine; D007855:Lead Poisoning / Q000188:drug therapy*; D008297:Male; D008517:Phytotherapy; D013607:Tablets
chemical_list: D004365:Drugs, Chinese Herbal; D013607:Tablets; D007854:Lead