title: Terphenyl-based helical mimetics that disrupt the p53/HDM2 interaction.
authors.affiliation: Department of Chemistry, Yale University, P.O. Box 208 107, New Haven, CT 06520-8107, USA, Fax: (+1) 203-432-6144.
authors.forename: Hang
authors.initials: H
authors.lastname: Yin
authors.affiliation: Department of Chemistry, Yale University, P.O. Box 208 107, New Haven, CT 06520-8107, USA, Fax: (+1) 203-432-6144.
authors.forename: Gui-In
authors.initials: GI
authors.lastname: Lee
authors.affiliation: Department of Chemistry, Yale University, P.O. Box 208 107, New Haven, CT 06520-8107, USA, Fax: (+1) 203-432-6144.
authors.forename: Hyung Soon
authors.initials: HS
authors.lastname: Park
authors.affiliation: Department of Chemistry, Yale University, P.O. Box 208 107, New Haven, CT 06520-8107, USA, Fax: (+1) 203-432-6144.
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Payne
authors.affiliation: Department of Chemistry, Yale University, P.O. Box 208 107, New Haven, CT 06520-8107, USA, Fax: (+1) 203-432-6144.
authors.forename: Johanna M
authors.initials: JM
authors.lastname: Rodriguez
authors.affiliation: Drug Discovery Program, H. Lee Moffitt Cancer Center and Research Institute, Departments of Oncology and Biochemistry and Molecular Biology, University of South Florida, Tampa, FL 33612, USA.
authors.forename: Said M
authors.initials: SM
authors.lastname: Sebti
authors.affiliation: Department of Chemistry, Yale University, P.O. Box 208 107, New Haven, CT 06520-8107, USA, Fax: (+1) 203-432-6144.
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Hamilton
mesh_terms: D040761:Biomimetic Materials / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D018360:Crystallography, X-Ray; D006801:Humans; D008958:Models, Molecular; D019906:Nuclear Magnetic Resonance, Biomolecular; D011485:Protein Binding / Q000187:drug effects; D020836:Protein Structure, Quaternary; D051736:Proto-Oncogene Proteins c-mdm2 / Q000037:antagonists & inhibitors / Q000378:metabolism*; D013730:Terphenyl Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D016159:Tumor Suppressor Protein p53 / Q000037:antagonists & inhibitors / Q000378:metabolism*
chemical_list: D013730:Terphenyl Compounds; D016159:Tumor Suppressor Protein p53; C497206:MDM2 protein, human; D051736:Proto-Oncogene Proteins c-mdm2