title: A cyclic hexapeptide comprising alternating alpha-aminoxy and alpha-amino acids is a selective chloride ion receptor.
abstract: In nonpolar solvents, the cyclic hexapeptide 2, which comprises alternating D-alpha-amino and D-alpha-aminoxy acids, adopts a C3-symmetric conformation with alternating eight (N--O turns)- and seven (gamma turns)-membered-ring hydrogen bonds. A series of anion-binding studies has suggested that 2 can function as an effective anion receptor that not only displays a high selectivity for chloride ions, but also the capability to extract chloride ions from aqueous solutions into organic phases.
authors.affiliation: Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China. yangdan@hku.hk
authors.forename: Dan
authors.initials: D
authors.lastname: Yang
authors.forename: Xiang
authors.initials: X
authors.lastname: Li
authors.forename: Yao
authors.initials: Y
authors.lastname: Sha
authors.forename: Yun-Dong
authors.initials: YD
authors.lastname: Wu
mesh_terms: D000586:Amination; D000596:Amino Acids / Q000737:chemistry*; D001965:Bromides / Q000737:chemistry; D002712:Chlorides / Q000737:chemistry*; D007477:Ions / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D010100:Oxygen / Q000737:chemistry*; D010456:Peptides, Cyclic / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000596:Amino Acids; D001965:Bromides; D002712:Chlorides; D007477:Ions; D010456:Peptides, Cyclic; D010100:Oxygen