Failure of systemic antibiotic in preventing sequential endogenous endophthalmitis of a bronchiectasis patient.
OBJECTIVE
To report a rare presentation of bilateral, sequential Pseudomonas aeruginosa endogenous endophthalmitis in a woman with bronchiectasis.


METHODS
Interventional case report.


METHODS
A 69-year-old woman with bronchiectasis developed right and then left endogenous endophthalmitis with the microbial of P. aeruginosa, even though a course of 3-week intravenous ceftazidime antibiotic was prescribed.


RESULTS
The presentation of endogenous endophthalmitis in the right eye was late, and final visual acuity was hand movements. The condition was recognized much earlier in the left eye, and the infection was treated early on with vitrectomy and intravitreal antibiotics. Visual acuity at 1 year was stable at 20/40.


CONCLUSIONS
Systemic antibiotic failed to eradicate the primary source of Pseudomonas infection in the bronchiectasis patient. Unusual, painful red eye may be the presenting feature of endogenous endophthalmitis. Early vitrectomy may be considered in endogenous endophthalmitis caused by virulent pathogens such P. aeruginosa.
Chan
Wai-Man
WM
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, People's Republic of China. cwm6373@netvigator.com
Liu
David T L
DT
Fan
Dorothy S P
DS
Lau
Teresa T Y
TT
Lam
Dennis S C
DS
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001082:Aqueous Humor / Q000382:microbiology; D001987:Bronchiectasis / Q000382:microbiology*; D002442:Ceftazidime / Q000627:therapeutic use*; D009877:Endophthalmitis / Q000188:drug therapy* / Q000382:microbiology; D015818:Eye Infections, Bacterial / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D011552:Pseudomonas Infections / Q000188:drug therapy* / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D013183:Sputum / Q000382:microbiology; D017211:Treatment Failure; D014792:Visual Acuity; D014822:Vitreous Body / Q000382:microbiology
D000900:Anti-Bacterial Agents; D002442:Ceftazidime