title: [Postoperative complications in lung cancer patients with moderate pulmonary hypofunction].
abstract: OBJECTIVE
  With the development of surgery treatment for lung cancer, the importance of preoperative pulmonary function assessment evoked more and more attention. This research was set to analyze postoperative complications of lung cancer patients with moderate pulmonary hypofunction, and explore associated factors.
  
  
  METHODS
  Statistic t test and Chi(2) test were used to compare postoperative complications of 31 patients with moderate pulmonary hypofunction and 62 patients with normal pulmonary function (control group), logistic regression was performed to find associated factors.
  
  
  RESULTS
  In the 31 patients with moderate pulmonary hypofunction, hypoxemia (41.9%), arrhythmia or cardiac dysfunction (25.8%), pulmonary inflammation (25.8%) were common postoperative complications; incidence of severe complications, such as respiratory failure, and cardiac failure, was 9.2%; in-hospital mortality was 3.2%. In control group, the occurrence rates were 16.1%, 8.1%, 9.6%, and 3.2%, accordingly, no in-hospital death occurred. Regression analysis showed that age and resection range associated with the occurrence of postoperative complications.
  
  
  CONCLUSIONS
  compared with control group, incidences of common postoperative complications in patients with moderate pulmonary hypofunction are remarkably increased, but severe complications and in-hospital mortality are not significantly high. Patients with older age and larger resection range have a high risk of develop complications.
authors.affiliation: Intensive Care Unit, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, 510060, P.R.China. sunnyma@163.com
authors.forename: Gang
authors.initials: G
authors.lastname: Ma
authors.forename: Quan-Guan
authors.initials: QG
authors.lastname: Su
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: Zhi-Wei
authors.initials: ZW
authors.lastname: Zhu
authors.forename: Chun-Mei
authors.initials: CM
authors.lastname: Wang
mesh_terms: D000367:Age Factors; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000209:etiology; D002294:Carcinoma, Squamous Cell / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D000860:Hypoxia / Q000209:etiology*; D008175:Lung Neoplasms / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008451:Maximal Voluntary Ventilation; D008875:Middle Aged; D009367:Neoplasm Staging; D011013:Pneumonectomy / Q000009:adverse effects* / Q000379:methods; D011183:Postoperative Complications; D012189:Retrospective Studies; D012307:Risk Factors