A new method to detect systemic inflammatory response syndrome by continuous monitoring system: an experimental study in rats.
A continuous monitoring system was designed for detection of systemic inflammatory response syndrome (SIRS) using spectrum analyser and local temperature mapping system with deep body thermometer. This method demonstrated significant increases of heart and respiratory rates and deep body temperature from normal levels within 120 minutes after lipopolysaccharide administration in rats. Our monitoring system appears promising for clinical detection of SIRS in the early stages to prevent multiple organ failure.
Matsui
T
T
Research Institute, Division of Biomedical Engineering, National Defense Medical College, Tokorozawa, Japan. matsuit@res.ndmc.ac.jp
Ishizuka
T
T
Ishihara
M
M
Suzuki
M
M
Kurita
A
A
Kikuchi
M
M
D000818:Animals; D001831:Body Temperature; D003936:Diagnosis, Computer-Assisted / Q000295:instrumentation / Q000379:methods*; D004562:Electrocardiography / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006339:Heart Rate; D008297:Male; D008991:Monitoring, Physiologic / Q000295:instrumentation* / Q000379:methods; D051381:Rats; D017207:Rats, Sprague-Dawley; D015656:Respiratory Mechanics; D013057:Spectrum Analysis / Q000295:instrumentation* / Q000379:methods; D018746:Systemic Inflammatory Response Syndrome / Q000175:diagnosis* / Q000503:physiopathology*; D018511:Systems Integration; D013817:Thermography / Q000295:instrumentation* / Q000379:methods