Highly efficient and direct heterocyclization of dipyridyl ketone to N,N-bidentate ligands.
[reaction: see text] Reaction of various aromatic aldehydes with 2,2'-dipyridyl ketone and ammonium acetate in hot acetic acid provides ready access to a series of substituted 1-pyridylimidazo[1,5-a]pyridines, a class of ligands possessing an N,N-bidentate feature, in good yields.
Wang
Jie
J
Department of Chemistry, Laboratory for Electro-Optical Materials & NASA Center for High Performance Polymers and Composites, Clark Atlanta University, Atlanta, Georgia 30314, USA.
Dyers
Leon
L
Mason
Richard
R
Amoyaw
Prince
P
Bu
Xiu R
XR
D015082:2,2'-Dipyridyl / Q000031:analogs & derivatives* / Q000737:chemistry*; D000447:Aldehydes / Q000737:chemistry; D003500:Cyclization; D008024:Ligands; D015394:Molecular Structure
C418768:2,2'-dipyridylketone; D000447:Aldehydes; D008024:Ligands; D015082:2,2'-Dipyridyl