title: Persistent rectal prolapse in children: sclerotherapy and surgical management.
abstract: Persistent rectal prolapse is an uncommon but distressing condition in children. Significant controversy exists regarding its surgical management. The aim of this study was to identify a successful management strategy for persistent rectal prolapse in the paediatric population. Records of all children with rectal prolapse treated surgically at Birmingham Children's Hospital between 1995 and 2003 were retrospectively reviewed. Demographic data, clinical presentation, investigations, treatment modality, complications, and outcome were recorded. Inclusion criteria for the study were failure of conservative management leading to operative treatment. An exclusion criterion was cystic fibrosis. A total of 24 patients with persistent rectal prolapse were identified. Two children with cystic fibrosis were excluded from the analysis. Children below the age of 5 years, group I (n=17), were successfully managed by submucous hypertonic saline injections. Eighty-three percent (14/17) were cured by injection sclerotherapy in this group, 12/14 (71%) requiring one injection and 2/14 requiring a second injection. In the three (17.6%) children in group I in whom sclerotherapy failed, cow's milk protein (CMP) allergy was identified as the causative factor. Children older than 5, group II (n=5), either had behavioural problems (n=3) or were autistic (n=2). This group of children with adult-type, full-thickness rectal prolapse were found to be refractory to initial attempts of injection sclerotherapy. All five children were successfully managed with surgical correction. We conclude that rectal submucous hypertonic saline injections are highly effective for managing early-onset idiopathic childhood rectal prolapse. CMP allergy should be considered in young children with recurrent rectal prolapse. We recommend early definitive corrective surgery in older children with persistent rectal prolapse, as they do not respond to conservative measures or injection sclerotherapy.
authors.affiliation: Department of Paediatric Surgery, Birmingham Children's Hospital NHS Trust, Steelhouse Lane, Birmingham, B4 6NH, UK.
authors.forename: A
authors.initials: A
authors.lastname: Shah
authors.forename: D
authors.initials: D
authors.lastname: Parikh
authors.forename: G
authors.initials: G
authors.lastname: Jawaheer
authors.forename: P
authors.initials: P
authors.lastname: Gornall
mesh_terms: D002675:Child, Preschool; D003672:Defecation; D006801:Humans; D012005:Rectal Prolapse / Q000150:complications / Q000601:surgery / Q000628:therapy*; D012189:Retrospective Studies; D012462:Saline Solution, Hypertonic / Q000627:therapeutic use; D015911:Sclerotherapy
chemical_list: D012462:Saline Solution, Hypertonic