title: Linezolid use associated with lactic acidosis.
abstract: Linezolid is a new synthetic antibiotic with a broad spectrum of activity against virtually all important Gram-positive infections. Lactic acidosis is a well known side-effect of metformin and nucleoside reverse-transcriptase inhibitors. We report a case in which lactic acidosis developed as an adverse effect of linezolid treatment.
authors.affiliation: Intensive Care Unit, 'Attikon' University Hospital, Athens, Greece. petkop@ath.forthnet.gr
authors.forename: Petros
authors.initials: P
authors.lastname: Kopterides
authors.forename: Evangelos
authors.initials: E
authors.lastname: Papadomichelakis
authors.forename: Apostolos
authors.initials: A
authors.lastname: Armaganidis
mesh_terms: D000081:Acetamides / Q000009:adverse effects*; D000140:Acidosis, Lactic / Q000139:chemically induced* / Q000175:diagnosis*; D000368:Aged; D000890:Anti-Infective Agents / Q000009:adverse effects*; D016470:Bacteremia / Q000188:drug therapy*; D003937:Diagnosis, Differential; D006801:Humans; D000069349:Linezolid; D016410:Lymphoma, T-Cell, Cutaneous; D008297:Male; D016106:Methicillin Resistance; D023303:Oxazolidinones / Q000009:adverse effects*; D013203:Staphylococcal Infections / Q000188:drug therapy*
chemical_list: D000081:Acetamides; D000890:Anti-Infective Agents; D023303:Oxazolidinones; D000069349:Linezolid