title: [ABO genotyping by duplex amplification and oligonucleotide arrays assay].
abstract: OBJECTIVE
  ABO genotyping for forensic identification by oligonucleotide chip.
  
  
  METHODS
  Oligonucleotide microarrays which could detect 3 different SNPs in exon 6 and exon 7 for ABO genotyping were used. Population studies on ABO was carried out in a sample of 115 unrelated Chinese Han individuals. The method was also applied to cases.
  
  
  RESULTS
  The technique could identify 6 genotypes of ABO system. According to the results of population studies, no significant deviations from Hardy-Weinberg equilibrium could be found. The observed and expected heterozygosities were 0.591 and 0.616 respectively. The polymorphic information content was 0.544. The average exclusion probabilities in buos and trios was 0.188 and 0.344 respectively. The discrimination power is 0.777.
  
  
  CONCLUSIONS
  The data and case application demonstrated that ABO typing by oligonucleotide probe arrays was a useful technique for paternity testing and individual identification.
authors.affiliation: Institute of Forensic Sciences, Ministry of Justice, PRChina, Shanghai 200063, China.
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.forename: Cheng-tao
authors.initials: CT
authors.lastname: Li
authors.forename: Rong-yu
authors.initials: RY
authors.lastname: Li
authors.forename: Meiqian
authors.initials: M
authors.lastname: Sun
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.forename: Yao
authors.initials: Y
authors.lastname: Li
authors.forename: Yuan
authors.initials: Y
authors.lastname: Lin
authors.forename: Tingzhi
authors.initials: T
authors.lastname: Que
authors.forename: Dalin
authors.initials: D
authors.lastname: Cheng
authors.forename: Pinhua
authors.initials: P
authors.lastname: Yan
authors.forename: Jianxin
authors.initials: J
authors.lastname: Fang
authors.forename: Zhenmin
authors.initials: Z
authors.lastname: Zhao
authors.forename: Min
authors.initials: M
authors.lastname: Shen
authors.forename: Zhichun
authors.initials: Z
authors.lastname: Du
mesh_terms: D000017:ABO Blood-Group System / Q000235:genetics*; D001801:Blood Stains; D004247:DNA / Q000097:blood; D017931:DNA Primers; D005260:Female; D005554:Forensic Medicine; D005838:Genotype; D006197:Hair / Q000737:chemistry; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis
chemical_list: D000017:ABO Blood-Group System; D017931:DNA Primers; D004247:DNA