title: CoC: a database of universally conserved residues in protein folds.
abstract: The conservatism of conservatism (CoC) database presents statistically analyzed information about the conservation of residue positions in folds across protein families.
  
  
  BACKGROUND
  On the web at http://kulibin.mit.edu/coc/
authors.affiliation: Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA.
authors.forename: Jason E
authors.initials: JE
authors.lastname: Donald
authors.forename: Isaac A
authors.initials: IA
authors.lastname: Hubner
authors.forename: Veronica M
authors.initials: VM
authors.lastname: Rotemberg
authors.forename: Eugene I
authors.initials: EI
authors.lastname: Shakhnovich
authors.forename: Leonid A
authors.initials: LA
authors.lastname: Mirny
mesh_terms: D017124:Conserved Sequence; D003628:Database Management Systems; D030562:Databases, Protein; D016247:Information Storage and Retrieval / Q000379:methods; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry* / Q000145:classification*; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods*; D017386:Sequence Homology, Amino Acid; D012984:Software; D014584:User-Computer Interface
chemical_list: D011506:Proteins