title: Esophageal diverticulum: a complication of histoplasmosis in children.
abstract: We report three boys, ages 8 to 14 years, who experienced dysphagia or chest pain while eating. In each patient, contrast esophagrams or esophagogastroduodenoscopy (EGD) demonstrated mid-esophageal traction diverticula, and serologic findings were compatible with acute or recent histoplasmosis. Diverticula appear to result from esophageal traction induced by inflammatory changes in adjacent infected lymph nodes. Antifungal and anti-inflammatory therapies were individualized in each case; all patients recovered fully.
authors.affiliation: Division of Pediatric Gastroenterology/Hepatology/Nutrition, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis 46202-5225, USA.
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Steiner
authors.forename: Elaine G
authors.initials: EG
authors.lastname: Cox
authors.forename: Sandeep K
authors.initials: SK
authors.lastname: Gupta
authors.forename: Martin B
authors.initials: MB
authors.lastname: Kleiman
authors.forename: Joseph F
authors.initials: JF
authors.lastname: Fitzgerald
mesh_terms: D000293:Adolescent; D000935:Antifungal Agents / Q000627:therapeutic use; D002637:Chest Pain / Q000209:etiology; D002648:Child; D003680:Deglutition Disorders / Q000209:etiology; D004936:Diverticulum, Esophageal / Q000175:diagnosis / Q000209:etiology*; D004435:Eating; D006660:Histoplasmosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole