Protein-lipid interactions of bacteriophage M13 gene 9 minor coat protein.
Gene 9 protein is one of the minor coat proteins of bacteriophage M13. The protein plays a role in the assembly process by associating with the host membrane by protein-lipid interactions. The availability of chemically synthesized protein has enabled the biophysical characterization of the membrane-bound state of the protein by using model membrane systems. This paper summarizes, discusses and further interprets this work in the light of the current state of the literature, leading to new possible models of the coat protein in a membrane. The biological implications of these findings related to the membrane-bound phage assembly are indicated.
Houbiers
M Chantal
MC
Laboratory of Biophysics, Wageningen University, Dreijenlaan 3, NL-6703 HA Wageningen, The Netherlands.
Hemminga
Marcus A
MA
D017104:Bacteriophage M13 / Q000737:chemistry* / Q000378:metabolism*; D036022:Capsid Proteins / Q000737:chemistry / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D050356:Lipid Metabolism; D011485:Protein Binding
D036022:Capsid Proteins; C117230:gene 9 minor coat protein, bacteriophage M13