title: Organophosphorus derivatives containing piperazine dithiosemicarbazones as chemotherapeutants against fungal pathogens of sugarcane.
abstract: Five novel organophosphorus derivatives have been synthesized by the reactions of O,O-diethylchlorophosphate with piperazine dithiosemicarbazones. The derivatives have been characterized on the basis of analyses and spectral (IR, 1H NMR) data. Fungicidal activities of these derivatives against Colletotrichum falcatum, Fusarium oxysporum, and Curvularia pallescence have been evaluated. The screening results have been correlated with the structural features of the tested compounds. Organophosphorus derivatives containing 1,4-bis(4-chlorobenzaldehyde)piperazine dithiosemicarbazone and 1,4-bis(4-methoxybenzaldehyde)piperazine dithiosemicarbazone proved to be more active than some prevalent commercial synthetic fungicides.
authors.affiliation: Chemistry Department, DDU Gorakhpur University, Gorakhpur 273009, India.
authors.forename: Ruchi
authors.initials: R
authors.lastname: Chandra
authors.forename: O P
authors.initials: OP
authors.lastname: Pandey
authors.forename: S K
authors.initials: SK
authors.lastname: Sengupta
mesh_terms: D001203:Ascomycota / Q000187:drug effects; D020231:Colletotrichum / Q000187:drug effects; D005659:Fungicides, Industrial / Q000138:chemical synthesis / Q000494:pharmacology*; D005670:Fusarium / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000138:chemical synthesis / Q000494:pharmacology*; D010879:Piperazines / Q000737:chemistry* / Q000494:pharmacology; D010935:Plant Diseases / Q000382:microbiology*; D031786:Saccharum / Q000382:microbiology*; D013055:Spectrophotometry, Infrared; D013329:Structure-Activity Relationship; D013882:Thiosemicarbazones / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D005659:Fungicides, Industrial; D009943:Organophosphorus Compounds; D010879:Piperazines; D013882:Thiosemicarbazones; C015848:dithiosemicarbazone