title: Treatment of osteoarthritis.
abstract: Osteoarthritis is a most common health problem in population over age 40 and a leading cause of pain and disability in the United States. Treatments of osteoarthritis incorporate combination of nonpharmacologic modalities, pharmacologic agents and surgical procedures. Unfortunately nonpharmacological modalities are underutilized in the management algorithm. In addition to physical and occupational therapy, diet and exercise play an extremely important role, thus patient education in the above areas is of great importance. Pharmacological measures should be examined carefully by physician and the patient weighting its existing risks and benefits. Surgical procedures are generally reserved for patients with severe arthritis who have persistent aim and significantly reduced function. Presently, there are no proven structure/disease-modifying interventions and therefore current therapy is aimed to symptom relief and rehabilitation.
authors.affiliation: Division of Rheumatology, Department of Medicine, University of Florida, Gainesville 32610, USA. barneev@medicine.ufl.edu
authors.forename: Elena V
authors.initials: EV
authors.lastname: Barnes
authors.forename: N Lawrence
authors.initials: NL
authors.lastname: Edwards
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001915:Braces; D016861:Cyclooxygenase Inhibitors / Q000627:therapeutic use; D004032:Diet; D005081:Exercise Therapy; D006801:Humans; D009985:Orthopedics / Q000379:methods; D010003:Osteoarthritis / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D016861:Cyclooxygenase Inhibitors