title: [Brachioradial pruritus: a rare, localized, neuropathic form of itching].
abstract: We report on a female patient with brachioradial pruritus, in whom the cause could be verified by purposeful diagnostics (e. g., MRI). The clinical symptoms with localized itching result from circumscribed nerve root compression and hyperexcitation of the nerve fibers. Under treatment with gabapentin, an anticonvulsant with a very good analgesic and good antipruritic effect, the itch ceased and the skin changes healed. This case shows that this special form of neuropathic itch requires targeted therapy, which apart from symptomatic treatment should primarily focus on remedying the cause, if feasible.
authors.affiliation: Klinik und Poliklinik für Hautkrankheiten, Universitätsklinikum Münster.
authors.forename: F
authors.initials: F
authors.lastname: Schürmeyer-Horst
authors.forename: R
authors.initials: R
authors.lastname: Fischbach
authors.forename: D
authors.initials: D
authors.lastname: Nabavi
authors.forename: D
authors.initials: D
authors.lastname: Metze
authors.forename: S
authors.initials: S
authors.lastname: Ständer
mesh_terms: D000588:Amines / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D002574:Cervical Vertebrae / Q000473:pathology; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use; D005260:Female; D005542:Forearm / Q000294:innervation*; D000077206:Gabapentin; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009192:Myelography; D009408:Nerve Compression Syndromes / Q000150:complications* / Q000175:diagnosis; D011537:Pruritus / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D017444:Skin Diseases, Papulosquamous / Q000188:drug therapy / Q000209:etiology*; D013126:Spinal Nerve Roots / Q000473:pathology*; D013128:Spinal Osteophytosis / Q000150:complications* / Q000175:diagnosis*; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use
chemical_list: D000588:Amines; D000927:Anticonvulsants; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin