Annexin A2: better left alone.
Zhang and McCrae demonstrate that APLA/b2GPI-mediated endothelial cell activation occurs via dimerization of annexin A2 molecules on the cell surface.
Wolberg
Alisa S
AS
University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Roubey
Robert A S
RA
D000818:Animals; D017306:Annexin A2 / Q000378:metabolism / Q000502:physiology*; D000906:Antibodies / Q000494:pharmacology; D017152:Antibodies, Antiphospholipid / Q000276:immunology; D019281:Dimerization; D004730:Endothelium, Vascular / Q000473:pathology*; D006023:Glycoproteins / Q000276:immunology; D006801:Humans; D019851:Thrombophilia / Q000209:etiology; D053482:beta 2-Glycoprotein I
D017306:Annexin A2; D000906:Antibodies; D017152:Antibodies, Antiphospholipid; D006023:Glycoproteins; D053482:beta 2-Glycoprotein I