title: Rare Helicobacter pylori infection as a factor for the very low stomach cancer incidence in Yogyakarta, Indonesia.
abstract: To elucidate factors associated with the very low risk of gastric neoplasia in Yogyakarta, Indonesia, approximately 1/50 of the level in Japan, we recruited 52 male and 39 female participants from the general populace in the city of Yogyakarta in October 2003. Helicobacter pylori IgG antibodies were found in only 5% (0-13) (95% confidence interval) and 4% (0-9) for Javanese males and females, respectively, and were statistically lower than the 62% (58-65) and 57% (53-60), respectively, in Japanese. Furthermore, positive findings of pepsinogen test were only 0 and 2% (0-6) for males and females, in Yogyakarta, and were again significantly lower than the 23% (22-25) and 22% (20-23), in Japan. The very low incidence of stomach cancer in Yogyakarta may be due to a low prevalence of H. pylori infection and chronic atrophic gastritis.
authors.affiliation: Department of Health Promotion and Preventive Medicine, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, Nagoya 467-8601, Japan. tokudome@med.nagoya-cu.ac.jp
authors.forename: Shinkan
authors.initials: S
authors.lastname: Tokudome
authors.lastname: Soeripto
authors.forename: F X Ediati
authors.initials: FX
authors.lastname: Triningsih
authors.forename: Indrawati
authors.initials: I
authors.lastname: Ananta
authors.forename: Sadao
authors.initials: S
authors.lastname: Suzuki
authors.forename: Kiyonori
authors.initials: K
authors.lastname: Kuriki
authors.forename: Susumu
authors.initials: S
authors.lastname: Akasaka
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kosaka
authors.forename: Hideki
authors.initials: H
authors.lastname: Ishikawa
authors.forename: Takeshi
authors.initials: T
authors.lastname: Azuma
authors.forename: Malcolm A
authors.initials: MA
authors.lastname: Moore
mesh_terms: D000328:Adult; D005260:Female; D016481:Helicobacter Infections / Q000453:epidemiology* / Q000276:immunology; D016480:Helicobacter pylori / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007214:Indonesia / Q000453:epidemiology; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D013274:Stomach Neoplasms / Q000453:epidemiology* / Q000382:microbiology*
chemical_list: D007074:Immunoglobulin G