title: Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update.
abstract: Interest in the relationships between the pharmacokinetics (PK) and pharmacodynamics (PD) of antimicrobial agents has increased over recent years. Since the appearance 2 years ago of our first article describing terminology in PK/PD, the field has continued to expand rapidly, urgently requiring an update. This paper describes in a uniform manner the use of PK/PD expressions for antimicrobial agents, and their units.
authors.affiliation: Department of Medical Microbiology and Infectious Diseases, Canisius Wilhelmina Hospital, Weg door Jonkerbos 100, 6532 sz Nijmegen, The Netherlands. Mouton@cwz.nl
authors.forename: Johan W
authors.initials: JW
authors.lastname: Mouton
authors.forename: Michael N
authors.initials: MN
authors.lastname: Dudley
authors.forename: Otto
authors.initials: O
authors.lastname: Cars
authors.forename: Hartmut
authors.initials: H
authors.lastname: Derendorf
authors.forename: George L
authors.initials: GL
authors.lastname: Drusano
mesh_terms: D000890:Anti-Infective Agents / Q000493:pharmacokinetics* / Q000494:pharmacology*; D019540:Area Under Curve; D006801:Humans; D008826:Microbial Sensitivity Tests; D009626:Terminology as Topic
chemical_list: D000890:Anti-Infective Agents