Urodynamic alterations in patients with HTLV-1 infection.
OBJECTIVE
The HTLV-1 is a retrovirus that causes several diseases, including tropical spastic paraparesis or HTLV-1 associated myelopathy (or TSP/HAM, as designated by the World Health Organization - WHO) described in 1985. In Brazil, the first cases were reported in 1989. In order to evaluate the urodynamic alterations of infected patients, 48 cases were studied: 26 TSP/HAM and 22 non-TSP/HAM.


METHODS
Evaluation was performed by testing, cystometry, abdominal pressure, differential pressure, detrusor leak point pressure, maximum flow pressure, and electromyography.


RESULTS
80.76% TSP/HAM patients showed hyperreflexic bladder, and 34.16% had detrusor-sphincter dyssinergia; 82.6% of this group had abnormal uroflow tests. Non-TSP/HAM patients had hyperreflexic bladders in 22.72% of the cases, and detrusor-sphincter dyssinergia was not assessed. For these patients, uroflow rate was normal in 70% of the cases.


CONCLUSIONS
Patients infected by the HTLV-1, with or without myelopathy, present significant urodynamic abnormalities and must have a complete urologic and urodynamic evaluation.
Lima
Cláudio L M
CL
Section of Urology, Porto Alegre General Hospital, Federal University of Rio Grande do Sul, Brazil.
Rabolini
Giorgio
G
Menna-Barreto
Márcio
M
Dos Santos
Emanuel B
EB
Koff
Walter J
WJ