title: Melatonin, refractory hypertension, myocardial ischemia and other challenges in nightly blood pressure lowering.
abstract: A test of the relative merits of timed melatonin for the treatment of cardiac ischemia as well as hypertension refractory to other drugs is documented against the background of earlier chronobiological studies on blood pressure (BP), disease risks, circadian hyper-amplitude-tension and melatonin effects broadly.
authors.affiliation: Department of Cardiology, Hospital 60, Moscow, Russia.
authors.forename: Rina Mikhailovna
authors.initials: RM
authors.lastname: Zaslavskaya
authors.forename: Galina Victorovna
authors.initials: GV
authors.lastname: Lilitsa
authors.forename: G S
authors.initials: GS
authors.lastname: Dilmagambetova
authors.forename: Franz
authors.initials: F
authors.lastname: Halberg
authors.forename: Germaine
authors.initials: G
authors.lastname: Cornélissen
authors.forename: Kuniaki
authors.initials: K
authors.lastname: Otsuka
authors.forename: Ram B
authors.initials: RB
authors.lastname: Singh
authors.forename: Alexander
authors.initials: A
authors.lastname: Stoynev
authors.forename: Ognian
authors.initials: O
authors.lastname: Ikonomov
authors.forename: Roberto
authors.initials: R
authors.lastname: Tarquini
authors.forename: Federico
authors.initials: F
authors.lastname: Perfetto
authors.forename: Othild
authors.initials: O
authors.lastname: Schwartzkopff
authors.forename: Earl E
authors.initials: EE
authors.lastname: Bakken
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000187:drug effects* / Q000502:physiology; D019454:Chronotherapy / Q000379:methods; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008550:Melatonin / Q000008:administration & dosage / Q000627:therapeutic use*; D015201:Meta-Analysis as Topic; D017202:Myocardial Ischemia / Q000188:drug therapy* / Q000503:physiopathology; D017211:Treatment Failure
chemical_list: D008550:Melatonin