title: A case of small cell gastric carcinoma with an adenocarcinoma component operated curatively.
abstract: We present a case of a primary advanced gastric tumor that was composed of 2 different pathological components: small cell carcinoma and moderately-differentiated adenocarcinoma. The patient was still alive four years after the surgery was performed, without recurrence. A large part of the tumor consisted of a diffuse sheet of small cell carcinoma, which transitioned into another small portion consisting of moderately-differentiated tubular adenocarcinoma components. Therefore, this case raised the possibility that small cell gastric carcinoma may originate from totipotential stem cells of the stomach. Although small cell carcinoma progresses aggressively, and patients with it have an extremely poor prognosis, this patient recovered uneventfully after the surgical resection, and has remained in good health, without any recurrences.
authors.affiliation: Department of Medicine, Koseiren Itoigawa General Hospital, Nügata 941 8502, Japan. yyata@toyama-mpu.ac.jp
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Yata
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Nakayama
authors.forename: Terumi
authors.initials: T
authors.lastname: Takahara
authors.forename: Kunio
authors.initials: K
authors.lastname: Yamazaki
authors.forename: Kiichi
authors.initials: K
authors.lastname: Masuyama
authors.forename: Masaru
authors.initials: M
authors.lastname: Sawataishi
authors.forename: Shuichiro
authors.initials: S
authors.lastname: Suzuki
authors.forename: Masanori
authors.initials: M
authors.lastname: Honma
authors.forename: Shin
authors.initials: S
authors.lastname: Ishizawa
authors.forename: Michio
authors.initials: M
authors.lastname: Tanaka
authors.forename: Akiharu
authors.initials: A
authors.lastname: Watanabe
authors.forename: Toshiro
authors.initials: T
authors.lastname: Sugiyama
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D000368:Aged; D018288:Carcinoma, Small Cell / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008297:Male; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D016896:Treatment Outcome