title: [Ceruloplasmin level of patients with liver disease in China].
abstract: OBJECTIVE
  To find out the degree of overlap of ceruloplasmin concentration in patients presenting with liver disease, providing scientific evidences for the diagnosis and differential diagnosis of Wilson's disease (WD).
  
  
  METHODS
  Measuring the serum ceruloplasmin concentration of patients presenting with liver diseases, all data were statistically analyzed with SPSS12 for Windows.
  
  
  RESULTS
  The average serum ceruloplasmin concentration of patients with WD was (93.9 +/- 98.1) mg/L, which was significantly lower than patients with non WD. The ceruloplasmin concentration of 72.7% of patients with WD was less than 100 mg/L, and that of 42.9% of patients with WD was less than 50 mg/L, but the ceruloplasmin concentration of 9.1% of patients with WD was more than 210 mg/L. The average serum ceruloplasmin concentration of patients with acute hepatitis was (398.4 +/- 151.3) mg/L, which was significantly higher than other group. The average serum ceruloplasmin concentration of patients with severe hepatitis was (296.5 +/- 106.5) mg/L, which was significantly lower than other group. The ceruloplasmin concentration of 6.8% of patients with non WD was less than 210 mg/L, the lowest was 28 mg/L.
  
  
  CONCLUSIONS
  There is some degree overlap in ceruloplasmin concentration between WD and other liver disease, WD could not be confirmed or excluded according to ceruloplasmin concentration only.
authors.affiliation: Liver Disease Research Center, The Second Xiangya Hospital, Central South University, Changsha 410011, China. yangxu@vip.163.com
authors.forename: Xu
authors.initials: X
authors.lastname: Yang
authors.forename: De-Jun
authors.initials: DJ
authors.lastname: Tong
authors.forename: Jun
authors.initials: J
authors.lastname: Liang
authors.forename: Yong-Hong
authors.initials: YH
authors.lastname: Zhang
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Lei
authors.forename: Xing-E
authors.initials: XE
authors.lastname: He
authors.forename: Gang
authors.initials: G
authors.lastname: He
mesh_terms: D002570:Ceruloplasmin / Q000032:analysis*; D002681:China; D003937:Diagnosis, Differential; D006527:Hepatolenticular Degeneration / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D008107:Liver Diseases / Q000097:blood / Q000175:diagnosis*
chemical_list: D002570:Ceruloplasmin