title: Efficacy of platelet gel in reconstructive bone surgery.
abstract: Autologous platelet concentrate and cryoprecipitate, mixed to obtain a gel, have been successful in various operations, primarily oral and maxillofacial surgery. This study assessed the use of platelet gel in 19 patients undergoing 22 reconstructive bone surgical procedures. After a median follow-up of 12.9 months, improved osteoblastic reaction and reconstruction of physiologic bone structure was observed in all patients with no adverse reactions. These findings confirm the osteoinductive property of platelet gel in reconstructive bone surgery.
authors.affiliation: Transfusion Service, Hospital of Verona, Verona, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Franchini
authors.forename: Paolo
authors.initials: P
authors.lastname: Dupplicato
authors.forename: Isabella
authors.initials: I
authors.lastname: Ferro
authors.forename: Marzia
authors.initials: M
authors.lastname: De Gironcoli
authors.forename: Roberto
authors.initials: R
authors.lastname: Aldegheri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip; D001792:Blood Platelets; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005782:Gels / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D019651:Plastic Surgery Procedures / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D005782:Gels