title: Skew-Laplace distribution in Gram-negative bacterial axenic cultures: new insights into intrinsic cellular heterogeneity.
abstract: The application of flow cytometry and skew-Laplace statistical analysis to assess cellular heterogeneity in Gram-negative axenic cultures is reported. In particular, fit to the log-skew-Laplace distribution for cellular side scatter or 'granulosity' is reported, and a number of theoretical and applied issues are considered in relation to the biological significance of this fit.
authors.affiliation: Departament d'Estadística, Facultat de Matemàtiques, Universitat de Barcelona, Gran Via, 585, 08007-Barcelona, Spain.
authors.forename: Olga
authors.initials: O
authors.lastname: Julià
authors.affiliation: Departament de Microbiologia, Universitat de Barcelona, Av. Diagonal, 645, 08028-Barcelona, Spain.
authors.forename: Josep
authors.initials: J
authors.lastname: Vives-Rego
mesh_terms: D003470:Culture Media; D003627:Data Interpretation, Statistical; D005434:Flow Cytometry / Q000706:statistics & numerical data; D006090:Gram-Negative Bacteria / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism; D016013:Likelihood Functions; D008962:Models, Theoretical
chemical_list: D003470:Culture Media