title: [Prevalence and risk factors for latex sensitization among anesthesiologists].
abstract: BACKGROUND
  Although powdered latex surgical gloves are predominantly used in Japanese healthcare facilities, the prevalence of latex sensitization among anesthesiologists has not been investigated.
  
  
  METHODS
  The authors surveyed 60 anesthesiologists of 16 facilities with questionnaires and measurements of specific IgE antibodies against latex and other aeroallergens by AlaSTAT microplate immunoassay. Sensitization was defined as positive if the specific IgE concentration was not less than 0.70 IU x ml(-1).
  
  
  RESULTS
  With surgical gloves 63.3% of anesthesiologists used powdered latex gloves, compared to 10.2% with examination gloves. The prevalence of latex sensitization was 33.3%, with a peak of 70% (7/10) in ages 45-49. In multivariate analysis, anesthesiologists of the facilities where more than 50% of them used powdered latex surgical gloves had a 6.0-fold risk of latex sensitization (95% CI 1.7-21.5; P=0.006). Histories of atopic dermatitis, asthma, or food allergy were also considered as risk factors (OR 3.8; 95% CI 1.1-13.7; P=0.038). The history of allergic rhinoconjunctivitis was not associated with latex allergen, but with Japanese cedar pollen. No relation was observed between latex and timothy pollen.
  
  
  CONCLUSIONS
  Our results suggest that surgical powdered latex gloves were the major predisposing factor for latex sensitization measured by latex-specific IgE among anesthesiologists.
authors.affiliation: Department of Anesthesia, Seikeikai Hospital, Sakai 590-0024.
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Tatsumi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Ide
authors.forename: Katsuyasu
authors.initials: K
authors.lastname: Kitaguchi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kato
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Kitagawa
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Furuya
mesh_terms: D000328:Adult; D000776:Anesthesiology; D000918:Antibody Specificity; D005260:Female; D005932:Gloves, Surgical / Q000009:adverse effects*; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D020315:Latex Hypersensitivity / Q000453:epidemiology* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D011795:Surveys and Questionnaires
chemical_list: D007073:Immunoglobulin E