title: Correlation between fetal gastric size and amniotic fluid volume.
abstract: OBJECTIVE
  Since abnormal conditions of the fetal digestive tract may alter both amniotic fluid volume and fetal gastric volume, we sought to determine whether amniotic fluid volume is correlated with fetal gastric volume in normal pregnancy.
  
  
  METHODS
  A total of 280 fetal gastric size measurements were made prospectively from routine sonographic examinations of women with normal singleton pregnancies between 16 and 42 weeks of gestation. The fetal stomach was defined as the largest area including the pyloric site on transverse or oblique real-time sonographic scans. Gastric volume was calculated according to the formula for a prolate ellipsoid. The amniotic fluid index (AFI) was used for the evaluation of amniotic fluid volume.
  
  
  RESULTS
  Both fetal gastric volume and AFI were significantly correlated with gestational age (R2= 0.422 and R2= 0.128, respectively). Only a weak correlation was found between gastric volume and AFI (R2= 0.036, p <0.001). On multivariate linear regression analysis adjusting for gestational age and fetal biometric measurements, gastric volume was not an independent and significant predictor of AFI.
  
  
  CONCLUSIONS
  Although sonographically determined fetal gastric volume measurements appear to be useful in the assessment of fetal digestive tract anomalies, fetal gastric volume has no clinically significant effect on the amniotic fluid volume in normal pregnancy.
authors.affiliation: Perinatal Division and WHO Collaborating Center for Perinatal Care, Department of Obstetrics and Gynecology, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, 49100, Israel.
authors.forename: Avi
authors.initials: A
authors.lastname: Ben-Haroush
authors.forename: Yariv
authors.initials: Y
authors.lastname: Yogev
authors.forename: Yoav
authors.initials: Y
authors.lastname: Peled
authors.forename: Jacob
authors.initials: J
authors.lastname: Bar
authors.forename: Moshe
authors.initials: M
authors.lastname: Hod
authors.forename: Josef
authors.initials: J
authors.lastname: Pardo
mesh_terms: D000653:Amniotic Fluid / Q000000981:diagnostic imaging*; D005260:Female; D005865:Gestational Age; D006801:Humans; D011237:Predictive Value of Tests; D011247:Pregnancy; D011446:Prospective Studies; D012016:Reference Values; D012044:Regression Analysis; D013270:Stomach / Q000000981:diagnostic imaging* / Q000196:embryology*; D016216:Ultrasonography, Prenatal