title: [Circadian rhythms of pineal gland melatonin-forming function in healthy elderly people].
abstract: Circadian rhythms of pineal gland melatonin-forming function were studied in healthy elderly people (n=31, age range 60-74 years). The blood plasma melatonin concentration was determined by means of radioimmune method at 3.00, 9.00, 15.00 and 21.00. The study revealed two types of circadian rhythms of plasma melatonin concentration: a high-amplitude (29%) and a low-amplitude (71%) ones. The high-amplitude rhythm of melatonin-forming pineal gland function was observed in elderly people with a higher physical working ability and a lower functional age of cardiovascular system. It is advisable to conduct the correction of pineal gland melatonin-forming function in elderly people with low-amplitude circadian rhythm of plasma melatonin concentration.
authors.forename: O V
authors.initials: OV
authors.lastname: Korkushko
authors.forename: V Kh
authors.initials: VKh
authors.lastname: Khavinson
authors.forename: V B
authors.initials: VB
authors.lastname: Shatilo
authors.forename: L V
authors.initials: LV
authors.lastname: Magdich
authors.forename: I F
authors.initials: IF
authors.lastname: Labunets
mesh_terms: D000368:Aged; D000375:Aging / Q000378:metabolism* / Q000502:physiology; D001831:Body Temperature / Q000502:physiology; D002940:Circadian Rhythm / Q000502:physiology*; D006801:Humans; D008550:Melatonin / Q000097:blood / Q000378:metabolism*; D008875:Middle Aged; D017440:Photoperiod; D010870:Pineal Gland / Q000378:metabolism / Q000502:physiology*; D012621:Seasons
chemical_list: D008550:Melatonin