title: [Reduction in the consumption of benzodiazepines due to a letter to chronic users from their own general practitioner].
abstract: OBJECTIVE
  To investigate the effectiveness of a minimal intervention in reducing the volume of prescription of benzodiazepines at the regional level.
  
  
  METHODS
  Prospective.
  
  
  METHODS
  Patients on compulsory health insurance who had received 180 or more daily doses of benzodiazepines in the course of one year received a letter from their general practitioner (GP) with information about the risks of chronic use, the advice to reduce or stop use, and an invitation to make an appointment to discuss the problem. This intervention took place in 19 GP practices in East Groningen. A reminder was sent six months later to the patients who had not responded in 9 randomly selected GP-practices. Thirty-seven practices in East Groningen and 91 practices in Northwest Groningen served as controls. Outcome measures were: (a) the percentage of patients who stopped, and (b) the change in average benzodiazepine consumption.
  
  
  RESULTS
  During the period 6-12 months after the first letter in the intervention group (n = 1343), 11.3% of the patients (95% CI: 9.6-13.1) received no prescription whatsoever for benzodiazepines compared to 5.4% (4.6-6.3) and 4.9% (4.2-5.5) in East Groningen (n = 2932) and in Northwest Groningen (n = 4562), respectively. The average decrease in prescription volume was 13% (-9.9 to -15.1) in the intervention group compared to 3% (-0.1 to -4.1) and 3% (-1.5 to -4) in the control groups. The reminder sent half a year later had no additional effect.
  
  
  CONCLUSIONS
  The informative letter from the GP to chronic users of benzodiazepines with the advice to stop or reduce this use was effective.
authors.affiliation: GGD Groningen, Hulpverleningsdienst, Postbus 584, 9700 AN Groningen. wim.niessen@hvd.groningen.nl
authors.forename: W J M
authors.initials: WJ
authors.lastname: Niessen
authors.forename: R E
authors.initials: RE
authors.lastname: Stewart
authors.forename: J
authors.initials: J
authors.lastname: Broer
authors.forename: F M
authors.initials: FM
authors.lastname: Haaijer-Ruskamp
mesh_terms: D014151:Anti-Anxiety Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001569:Benzodiazepines / Q000009:adverse effects* / Q000627:therapeutic use; D002908:Chronic Disease; D011307:Drug Prescriptions / Q000706:statistics & numerical data*; D005194:Family Practice; D005260:Female; D006801:Humans; D008297:Male; D009426:Netherlands; D010353:Patient Education as Topic / Q000379:methods*; D011446:Prospective Studies; D013375:Substance Withdrawal Syndrome / Q000517:prevention & control; D016896:Treatment Outcome
chemical_list: D014151:Anti-Anxiety Agents; D001569:Benzodiazepines