Toxic neuropathies.
Many substances, organic and manufactured, may induce peripheral nerve damage when exposed to them. The expected clinical phenotype is of a distal, sensory or sensorimotor polyneuropathy, often painful, with axonal characteristics on electrodiagnostic and histopathologic analysis. Treatment is limited; often, the only effective management is supportive care and avoidance from or removal of the offending toxin. Fortunately, the majority of toxic neuropathies are self-limited and improves gradually after toxin elimination.
Grogan
Patrick M
PM
Department of Neurology, Wilford Hall Medical Center, San Antonio, TX 78236, USA. patrick.grogan@lackland.af.mil
Katz
Jonathan S
JS
D000818:Animals; D006801:Humans; D020258:Neurotoxicity Syndromes / Q000209:etiology / Q000503:physiopathology; D009498:Neurotoxins / Q000009:adverse effects*; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced / Q000503:physiopathology
D009498:Neurotoxins