Cholesterol emboli-induced renal failure and gastric ulcer after thrombolytic therapy.
Cholesterol embolization syndrome is a rare but devastating complication of thrombolysis. Clinical presentations are variable, which has resulted in labeling this syndrome as the great masquerader. Almost every organ in the body may be affected, but the syndrome commonly involves the kidney, skin, central nervous system, and gastrointestinal tract. Treatment is mainly supportive, with an emphasis on reducing the risk of recurrence. The case presented is a unique one of thrombolytic-induced cholesterol embolization syndrome causing renal failure, in which the diagnosis was supported by a biopsy of a gastric ulcer.
Hitti
Wassim A
WA
Department of Internal Medicine, Franklin Square Hospital Center, Baltimore, MD 21218, USA. wassimhitti@yahoo.com
Anderson
John
J
D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use; D017700:Embolism, Cholesterol / Q000150:complications*; D005260:Female; D006493:Heparin / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology*; D011379:Prognosis; D013276:Stomach Ulcer / Q000139:chemically induced*; D015912:Thrombolytic Therapy / Q000009:adverse effects*
D000925:Anticoagulants; D006493:Heparin