Degradation of 1,4-dioxane and cyclic ethers by an isolated fungus.
By using 1,4-dioxane as the sole source of carbon, a 1,4-dioxane-degrading microorganism was isolated from soil. The fungus, termed strain A, was able to utilize 1,4-dioxane and many kinds of cyclic ethers as the sole source of carbon and was identified as Cordyceps sinensis from its 18S rRNA gene sequence. Ethylene glycol was identified as a degradation product of 1,4-dioxane by the use of deuterated 1,4-dioxane-d8 and gas chromatography-mass spectrometry analysis. A degradation pathway involving ethylene glycol, glycolic acid, and oxalic acid was proposed, followed by incorporation of the glycolic acid and/or oxalic acid via glyoxylic acid into the tricarboxylic acid cycle.
Nakamiya
Kunichika
K
Endocrine Disrupters and Dioxins Research Project, National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki 305-8506, Japan. Nakamiya.Kunichika@nies.go.jp
Hashimoto
Syunji
S
Ito
Hiroyasu
H
Edmonds
John S
JS
Morita
Masatoshi
M
D001673:Biodegradation, Environmental; D032661:Cordyceps / Q000235:genetics / Q000254:growth & development / Q000302:isolation & purification / Q000378:metabolism*; D004271:DNA, Fungal / Q000235:genetics; D004146:Dioxanes / Q000378:metabolism*; D004988:Ethers, Cyclic / Q000378:metabolism*; D007700:Kinetics; D008954:Models, Biological; D008969:Molecular Sequence Data; D012331:RNA, Fungal / Q000235:genetics; D012337:RNA, Ribosomal, 18S / Q000235:genetics; D012988:Soil Microbiology
D004271:DNA, Fungal; D004146:Dioxanes; D004988:Ethers, Cyclic; D012331:RNA, Fungal; D012337:RNA, Ribosomal, 18S; C025223:1,4-dioxane