A case of toxic epidermal necrolysis with lesions mostly on sun-exposed skin.
Toxic epidermal necrolysis (TEN) is a cutaneous, mostly drug-induced reaction pattern characterized by a widespread necrosis and exfoliation of epidermis, involving more than 30% of the body surface area. Photo-induced Stevens-Johnson syndrome and erythema multiforme, which belong to the same spectrum of TEN, have been described before. However, there is only one case of TEN limited to sun-exposed areas, which was caused by clobazam. In this report a second case of TEN because of naproxen, with lesions showing clear-cut borders on sun-exposed body areas resembling a sun-burn reaction, is presented.
Mansur
A T
AT
Department of Dermatology, Haydarpaşa Numune Training and Research Hospital, Istanbul, Turkey. tulinmansur@hotmail.com
Aydingöz
I A
IA
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D009288:Naproxen / Q000009:adverse effects*; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D013472:Sunlight / Q000009:adverse effects*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D009288:Naproxen