Central venous catheter-associated fungemia due to Wangiella dermatitidis.
Central venous catheter-related Wangiella dermatitidis infection has been increasingly reported in the recent literature. We report a case of central venous catheter (Port-A-Cath)-related fungemia caused by W. dermatitidis in a 58-year-old woman with lung cancer. Two W. dermatitidis isolates were recovered from 2 blood samples drawn from a peripheral vein and the Port-A-Cath 4 months after its placement. The minimum inhibitory concentrations of 2 isolates to fluconazole and amphotericin B using the standard broth microdilution method were 48 microg/mL and 0.19 microg/mL, respectively. The Port-A-Cath was removed and the fungemia responded to amphotericin B treatment. W. dermatitidis should be categorized as a pathogen that can cause central venous catheter-associated fungemia, particularly in immunocompromised patients.
Tseng
Ping-Huei
PH
Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.
Lee
Peilin
P
Tsai
Tzu-Hsiu
TH
Hsueh
Po-Ren
PR
D002405:Catheterization, Central Venous / Q000009:adverse effects*; D005093:Exophiala / Q000302:isolation & purification*; D005260:Female; D016469:Fungemia / Q000209:etiology*; D006801:Humans; D016867:Immunocompromised Host; D008875:Middle Aged; D009181:Mycoses / Q000382:microbiology*