[The effect of lipoproteins on signal transduction in thrombocytes and vascular wall cells].
In recent decades, studies have shown that lipoproteid physiological role goes beyond just their part in lipid transport. Database is accumulating on connection of lipoproteid pathological effects upon cardiovascular system with their ability to interfere in the signal transmission processes necessary for normal control of the vascular homeostasis. There is some evidence that lipoproteids are capable of affecting vascular tonus, coagulation balance, and inflammatory processes in the vascular wall. These effects will be realized through activation of the blood cell and vascular wall signal systems and can accelerate development of atherosclerosis and prompt hypertension and arterial thrombophilia.
Bochkov
V N
VN
Tkachuk
V A
VA
D000818:Animals; D001161:Arteriosclerosis / Q000209:etiology; D001792:Blood Platelets / Q000502:physiology*; D001808:Blood Vessels / Q000473:pathology / Q000503:physiopathology*; D004730:Endothelium, Vascular / Q000503:physiopathology; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000473:pathology / Q000503:physiopathology; D006973:Hypertension / Q000209:etiology / Q000503:physiopathology; D008074:Lipoproteins / Q000378:metabolism / Q000502:physiology*; D009131:Muscle, Smooth, Vascular / Q000473:pathology / Q000503:physiopathology; D015398:Signal Transduction; D013927:Thrombosis / Q000097:blood / Q000209:etiology / Q000503:physiopathology
D008074:Lipoproteins