title: [The effect of AM3 in the resolution of otitis media with effusion (OME) in paediatric patients].
abstract: OBJECTIVE
  Otitis media with effusion (OME) is one of the most frequent diseases and the main cause of hearing loss in childhood. The medical treatment for OME includes antibiotics, antihistamine-decongestant combinations, steroids and Eustachian-tube autoinflation as the Valsalva manoeuvre.
  
  
  METHODS
  A total of 62 children aged 2 to 8 years with a diagnosis of OME were enrolled in a prospective study to assess the resolution of OME. Patients were given antibiotics treatment with or without associated AM3.
  
  
  RESULTS
  After 2 months of treatment, the rate of complete resolution of OME was greater in AM3 treated group than in the non-AM3 treated group (57.6% vs 27.6%) with a statistically significant difference (p<0.017).
  
  
  CONCLUSIONS
  These results show that AM3 treatment has a beneficial effect on OME resolution when it is associated to antibiotic treatment.
authors.affiliation: Servicio de Otorrinolaringología, Hospital General de Móstoles, Móstoles, Madrid. primiortega@ffomc.org
authors.forename: P
authors.initials: P
authors.lastname: Ortega del Alamo
authors.forename: T
authors.initials: T
authors.lastname: Rivera Rodríguez
authors.forename: R
authors.initials: R
authors.lastname: Sanz Fernández
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology* / Q000627:therapeutic use*; D002130:Calcium Phosphates / Q000494:pharmacology* / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006020:Glycopeptides / Q000494:pharmacology* / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010034:Otitis Media with Effusion / Q000188:drug therapy*; D011446:Prospective Studies
chemical_list: D000276:Adjuvants, Immunologic; D002130:Calcium Phosphates; D006020:Glycopeptides; C038773:Immunoferon