[Intensity of the production of rheumatoid factor in patients with different degree of sensitization to Borrelia garinii antigens].
The content of rheumatoid factor and serum IgA, IgM and IgG in patients with different degree of sensitization to B. garinii antigens is evaluated. An increase in the titer of rheumatoid factor in patients with a high content of antibodies to Borrelia was established. In addition, an increased concentration of serum immunoglobulins in the presence of Borrelia infection was registered. The mechanisms of autoimmune reactions are discussed, proceeding from the biological properties of the causative agent of Lyme disease.
Kologrivova
E N
EN
Baraulina
A S
AS
Nechaeva
S V
SV
Shestakova
I I
II
Stronin
O V
OV
Vlasova
N M
NM
Sal'nikova
O M
OM
D000328:Adult; D000942:Antigens, Bacterial / Q000276:immunology*; D001172:Arthritis, Rheumatoid / Q000097:blood / Q000209:etiology*; D001323:Autoantibodies / Q000097:blood*; D015748:Borrelia burgdorferi Group / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D007114:Immunization; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008193:Lyme Disease / Q000097:blood / Q000150:complications* / Q000276:immunology; D008875:Middle Aged; D012217:Rheumatoid Factor / Q000097:blood*
D000942:Antigens, Bacterial; D001323:Autoantibodies; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012217:Rheumatoid Factor