[Quantitative morphometry of hyperplastic hypoechoic nodules in the prostatic outer gland].
OBJECTIVE
To explore the morphotic characteristics of hypoechoic nodules in the outer gland of the prostate with benign


METHODS
Twenty-two hyperplastic hypoechoic nodules in the prostatic outer gland were biopsied guided by prostatic hyperplasia. transrectal ultrasound. The hematoxylin-eosin (HE) staining and immunohistochemistry combined with computer assisted quantitative image analyses were adopted to examine the mean percentages of the area densities of stroma, epithelium, glandular lumen and smooth muscle cells.


RESULTS
The area densities of stroma, epithelium, glandular lumen and smooth muscle cells were (72.52 +/- 13.14)%, (20.57 +/- 9.01)%, (6.85 +/- 4.51)% and (24.14 +/- 6.31)%, respectively.


CONCLUSIONS
Hyperplastic hypoechoic nodules may develop in the outer gland as well as in the inner gland of the prostate, but the mean percentages of the components are different between the two kinds of nodules.
Li
Xin
X
Department of Ultrasonics, General Hospital of PLA, Beijing 100853, China. lx0803@sina.com.en
Wang
Na
N
Shi
Huai-Yin
HY
Zhang
Yan
Y
Fu
Xian-Shui
XS
Li
Jun-Lai
JL
Xu
Jian-Hong
JH
Tang
Jie
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D004848:Epithelium / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009130:Muscle, Smooth / Q000000981:diagnostic imaging / Q000473:pathology; D011467:Prostate / Q000000981:diagnostic imaging / Q000473:pathology*; D011470:Prostatic Hyperplasia / Q000000981:diagnostic imaging / Q000473:pathology*; D014463:Ultrasonography