title: Densitometric and tomographic analyses of musculoskeletal interactions in humans.
abstract: Previous studies with standard densitometry (DXA) have suggested that the bone mass is strongly dependent on the muscle mass in the species, following a similar relationship at any age and sex hormones or related factors potentiate that relationship. Studies with pQCT indicated that the surplus bone mass per unit of muscle mass previously observed in premenopausal women would be stored in skeletal regions with relatively little mechanical relevance, thus avoiding remotion through mechanically oriented remodelling by the bone mechanostat. Scanning the distal radius with pQCT has also showed a highly significant, linear relationship between SSI of the distal radius and the dynamometric maximal bending moment of the forearm in normal men and women. In order to investigate similar relationships in regions that are inaccessible to pQCT, we used spinal radiographs and axial QCT. This study affords additional evidence to the previous references concerning the direct, significant impact of the regional muscle strength on the determination of the tomographic indicators of bone mechanical quality and their indirect repercussion of the skeletal condition (curvature of the spine).
authors.affiliation: Centre for Ca-P Metabolism Studies (CEMFoC), Natl. Univ. of Rosario, Argentina.
authors.forename: J L
authors.initials: JL
authors.lastname: Ferretti
authors.forename: R F
authors.initials: RF
authors.lastname: Capozza
authors.forename: G R
authors.initials: GR
authors.lastname: Cointry
authors.forename: R
authors.initials: R
authors.lastname: Capiglioni
authors.forename: E J
authors.initials: EJ
authors.lastname: Roldan
authors.forename: J R
authors.initials: JR
authors.lastname: Zanchetta