[Natural history of a suspicious renal mass in a patient with gastric cancer: how to evaluate the risk of multiple primary tumours (MPT)?].
The coexistence of several tumours in the same patient is a rare phenomenon and corresponds to the multiple primary tumour (MPT) syndrome. The most frequently diagnosed MPT include gastrointestinal tumours associated with urological tumours. Overexpression of the STAG1 gene could explain the development of several solid tumours and could be the origin of the multiple primary tumour syndrome. A suspicious renal mass discovered at the same time as a documented cancer is usually a malignant lesion and may justify combined radical surgical treatment. The authors report the natural history of a suspicious renal mass in a patient with primary gastric tumour corresponding to a MPT syndrome. They recall and discuss the epidemiology, pathophysiology, diagnosis and treatment of MPT.
Van Agt
Guillaume
G
Services d'Urologie-Transplantation, CHU d'Amiens, France.
Bracq
Arnaud
A
Chatelain
Denis
D
Fourmarier
Marc
M
Regimbeau
Jean Marc
JM
Verhaeghe
Pierre
P
Petit
Jacques
J
Saint
Fabien
F
D000230:Adenocarcinoma / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D013274:Stomach Neoplasms / Q000175:diagnosis*