Familial occurrence of axillary papular mucinosis.
Primary cutaneous mucinosis encompasses a wide range of different skin conditions with circumscribed, follicular or diffuse manifestation. For the first time, to our knowledge, we report on the occurrence of so-called "atypical" localized papular mucinosis in the axillary pits of a mother and her (identical) twin daughters presenting as asymptomatic soft minuscule papules. This unique observation allows us to define an autosomal dominant inheritance pattern with a high level of penetrance for this rare skin disease.
Scheidegger
E Paul
EP
Dept. of Dermatology, Kantonsspital Aarau, 501.1 Aarau, Switzerland. pscheid@mydiax.ch
Itin
Peter
P
Kempf
Werner
W
D000293:Adolescent; D000328:Adult; D001365:Axilla; D004200:Diseases in Twins / Q000235:genetics*; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D017520:Mucinoses / Q000235:genetics* / Q000473:pathology; D012595:Scleroderma, Systemic / Q000235:genetics* / Q000473:pathology; D017444:Skin Diseases, Papulosquamous / Q000235:genetics* / Q000473:pathology; D013967:Thyroiditis, Autoimmune / Q000235:genetics / Q000473:pathology; D014430:Twins, Monozygotic / Q000235:genetics*