[UV-vis spectroscopic characterization of inclusion compounds of beta-cyclodextrin with lycopene].
Water-soluble inclusion compounds of beta-cyclodextrin with lycopene were prepared by two methods: (1) complexation in solution and (2) complexation by kneading. It was found that UV-Vis spectra of the inclusion complexes in water are different from those of lycopene in water-miscible organic solvents (tetrahydrofuran) and beta-cyclodextrin in water, which confirms the formation of the inclusion complexes. Specific interactions of lycopene and beta-cyclodextrin cause great changes in absorbance maximum (lambdamax) of lycopene. It is considered that the inclusion complexes in water are formed as supermolecular aggregates with nanometer size, after card-pack type lycopene is included by beta-cyclodextrin in molecular level.
Wang
Luo-xin
LX
Textile College, Sichuan University, Chengdu 610065, China.
Lü
Jun
J
Du
Zong-liang
ZL
Li
Rui-xia
RX
Wu
Da-cheng
DC
D002338:Carotenoids / Q000737:chemistry*; D002626:Chemistry, Pharmaceutical / Q000379:methods; D004355:Drug Stability; D000077276:Lycopene; D008956:Models, Chemical; D012995:Solubility; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet / Q000379:methods*; D013057:Spectrum Analysis; D014867:Water / Q000737:chemistry; D047392:beta-Cyclodextrins / Q000737:chemistry*
D047392:beta-Cyclodextrins; D014867:Water; D002338:Carotenoids; C031215:betadex; D000077276:Lycopene