[Anti-atherosclerotic effect of Ca channel antagonist].
Although anti-atherosclerotic effects of Ca channel antagonists have been shown in animal studies, clinical trials have failed to show such effects in humans. In those clinical studies, Ca channel antagonists did not retard progression or induce regression of atherosclerosis, however, they seemed to inhibit development of new atherosclerotic lesions. In this review, current knowledge of anti-atherosclerotic effects of Ca channel antagonists will be discussed with a special reference to the results of recent clinical trials.
Hirakawa
Y
Y
Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyusyu University.
Shimokawa
H
H