title: Views of bereaved relatives about quality of survival after radiotherapy for malignant cerebral glioma.
abstract: OBJECTIVE
  To explore the views of bereaved relatives about quality of survival after radiotherapy for malignant cerebral glioma.
  
  
  METHODS
  Semistructured interviews with the bereaved relatives of 56 previously studied patients with glioma.
  
  
  METHODS
  Patients treated at six London hospitals from 1990 to 1992 surviving between one and 46 months (median, eight).
  
  
  METHODS
  Fifty six relatives (44 spouses, 12 others) seen four to six months after bereavement and 20 again at 13 months.
  
  
  METHODS
  Views about quality of life and satisfaction with radiotherapy.
  
  
  RESULTS
  Relatives described quality of life as "good or acceptable" when patients carried on some normal activities or enjoyed social relationships. They described restricted and dependent states, constant deterioration, or loss of social interaction as giving "poor or unacceptable" quality of life. Length of time lived in such states also appeared important. Relatives' views of good or acceptable quality of life were independently related to low initial cognitive or personality change or low distress in the patient after diagnosis, and to their subsequent survival free from physical disability for at least one month. Satisfaction with radiotherapy was related to low initial distress, some degree of surgical resection, and overall length of survival longer than six months.
  
  
  CONCLUSIONS
  Carefully exploring the views of bereaved relatives can bring a useful perspective to difficult treatment decisions. Their values support including disability and distress in quality of life measures, but cast doubt on the QALY-type approach of using full years of survival or time free from disability to judge whether treatments are worthwhile.
authors.affiliation: Department of Neurological Sciences, St. Bartholomew's Hospital, West Smithfield, London EC1A 7BE, UK. elizabethdavies@doctors.org.uk
authors.forename: E
authors.initials: E
authors.lastname: Davies
authors.forename: C
authors.initials: C
authors.lastname: Clarke
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001294:Attitude to Health; D001601:Bereavement; D001932:Brain Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D003072:Cognition Disorders / Q000209:etiology; D005190:Family / Q000523:psychology*; D005260:Female; D005910:Glioma / Q000401:mortality / Q000532:radiotherapy*; D006801:Humans; D007406:Interview, Psychological; D008297:Male; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology*; D011878:Radiotherapy / Q000009:adverse effects; D013534:Survival / Q000523:psychology*