title: The effect of subthalamic nucleus stimulation on kinaesthesia in Parkinson's disease.
abstract: BACKGROUND
  Parkinson's disease is accompanied by deficits in passive motion and limb position sense.
  
  
  OBJECTIVE
  To investigate whether deep brain stimulation of the subthalamic nucleus (STN-DBS) reverses these proprioceptive deficits.
  
  
  RESULTS
  A passive movement task was applied to nine patients with Parkinson's disease and bilateral chronic STN-DBS and to seven controls. Thresholds for 75% correct responses were 0.9 degrees for controls, 2.5 degrees for Parkinson's disease patients when stimulation was OFF, and 2.0 degrees when stimulation was ON.
  
  
  CONCLUSIONS
  STN-DBS improves kinaesthesic deficits in Parkinson's disease, but does not lead to a full recovery of proprioceptive function.
authors.affiliation: Sensorimotor Control Laboratory, Division of Kinesiology, University of Minnesota, Minneapolis, MN, USA. matthias.maschke@uni-essen.de
authors.forename: M
authors.initials: M
authors.lastname: Maschke
authors.forename: P J
authors.initials: PJ
authors.lastname: Tuite
authors.forename: K
authors.initials: K
authors.lastname: Pickett
authors.forename: T
authors.initials: T
authors.lastname: Wächter
authors.forename: J
authors.initials: J
authors.lastname: Konczak
mesh_terms: D000328:Adult; D000368:Aged; D046690:Deep Brain Stimulation; D005260:Female; D006801:Humans; D007699:Kinesthesis / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000503:physiopathology* / Q000628:therapy*; D020127:Recovery of Function; D020531:Subthalamic Nucleus / Q000503:physiopathology*