Diffusivity and solubility of nitric oxide in water and saline.
Aqueous diffusivities and solubilities of NO were determined by using a chemiluminescence detector to measure time-dependent fluxes across stagnant liquid films confined between polydimethylsiloxane membranes. The NO diffusivities in pure water and PBS at 25 degrees C were found to be (2.21+/-0.02) x 10(-5) cm2 s(-1) and (2.21+/-0.04) x 10(-5) cm2 s(-1), respectively. Although lower than most previous values for NO at room temperature, these diffusivities are very similar to those for O2, as one would expect. Extrapolation to 37 degrees C yielded a value of 3.0 x 10(-5) cm2 s(-1). The solubility of NO in water at 25 degrees C was (1.94+/-0.03) x 10(-6) mol cm(-3) atm(-1), in agreement with the literature. This agreement, along with the excellent fits obtained to the transient flux data (<4% rms error in each experiment), supports the validity of the simultaneously measured diffusivity. The solubility of NO in PBS at 25 degrees C was (1.75+/-0.02) x 10(-6) mol cm(-3) atm(-1). The modest (10%) reduction in solubility relative to that in pure water is consistent with the usual effects of salts on gas solubilities.
Zacharia
Ian G
IG
Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Deen
William M
WM
D004058:Diffusion; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008163:Luminescent Measurements / Q000295:instrumentation* / Q000379:methods*; D008567:Membranes, Artificial; D009569:Nitric Oxide / Q000032:analysis* / Q000737:chemistry*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012965:Sodium Chloride / Q000737:chemistry*; D012995:Solubility; D014867:Water / Q000737:chemistry*
D008567:Membranes, Artificial; D014867:Water; D009569:Nitric Oxide; D012965:Sodium Chloride