Tetraploidy or near-tetraploidy clones with double 8;21 translocation: a non-random additional anomaly of acute myeloid leukemia with t(8;21)(q22;q22).
We report on 6 patients with tetraploidy or near-tetraploidy acute myeloid leukemia (AML) with double t(8;21) (q22;q22) and review the literature on cases with the same cytogenetic abnormalities. Some common features were revealed by this analysis.
Xiao
Zhijian
Z
Liu
Shihe
S
Liu
Xuping
X
Yu
Minghua
M
Hao
Yushu
Y
D000208:Acute Disease; D002891:Chromosomes, Human, Pair 21; D002898:Chromosomes, Human, Pair 8; D002999:Clone Cells; D006801:Humans; D007951:Leukemia, Myeloid / Q000235:genetics* / Q000473:pathology; D011123:Polyploidy; D011379:Prognosis; D014178:Translocation, Genetic