title: A novel pentacyclic triterpene from Leontodon filii.
abstract: A novel oleanene triterpenetetrol was isolated from the chloroform extract of the aerial parts of Leontodon filii. Its structure was shown to be 2beta,3beta,15alpha,21beta-olean-12-ene-2,3,15,21-tetrol by chemical and spectroscopic methods. The fungicidal efficacy of the chloroform and methanol extracts of the plant was also evaluated, a protective effect being found against Plasmopara viticola, Botrytis cinerea, particularly powerful against Pyricularia oryzae.
authors.affiliation: Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade de Lisboa, Lisboa, Portugal.
authors.forename: Zélia
authors.initials: Z
authors.lastname: Tostão
authors.forename: João P
authors.initials: JP
authors.lastname: Noronha
authors.forename: Eurico J
authors.initials: EJ
authors.lastname: Cabrita
authors.forename: Jorge
authors.initials: J
authors.lastname: Medeiros
authors.forename: Jorge
authors.initials: J
authors.lastname: Justino
authors.forename: Jaime
authors.initials: J
authors.lastname: Bermejo
authors.forename: Amélia P
authors.initials: AP
authors.lastname: Rauter
mesh_terms: D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D019659:Asteraceae; D006801:Humans; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects*; D008517:Phytotherapy; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D014315:Triterpenes / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D010936:Plant Extracts; D014315:Triterpenes