title: Self-administered screening for mild cognitive impairment: initial validation of a computerized test battery.
abstract: The Computer-Administered Neuropsychological Screen for Mild Cognitive Impairment (CANS-MCI), a computer administered, scored, and interpreted touch screen battery was evaluated for its ability to detect mild cognitive impairment. Subjects were three hundred ten community-dwelling elders who enrolled in an National Institute on Aging (NIA)-funded study. One-month test-retest reliability correlations were all significant (p<0.05-p<0.001). Concurrent validity correlations were all significant (p<0.001). A high level of diagnostic validity was attained relative to the Weschler Memory Scale-Revised (WMS-R) LMS-II test (p<0.001). Confirmatory factor analysis supported a three-factor model indicating the tests measure the intended cognitive dimensions of memory, language/spatial fluency, and executive function/mental control. Goodness-of-fit indicators were strong (Bentler Comparative Fit Index=0.99; Root Mean Square Error of Approximation=0.055). Initial validation analyses indicate that the CANS-MCI shows promise of being a reliable, valid screening tool in determining whether more intensive testing for early cognitive impairment is warranted.
authors.affiliation: Screen Inc. 3511 46th Ave. NE, Seattle, WA 98105, USA. JBTornatore@comcast.net
authors.forename: Jane B
authors.initials: JB
authors.lastname: Tornatore
authors.forename: Emory
authors.initials: E
authors.lastname: Hill
authors.forename: Jo Anne
authors.initials: JA
authors.lastname: Laboff
authors.forename: Mary E
authors.initials: ME
authors.lastname: McGann
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D003072:Cognition Disorders / Q000175:diagnosis* / Q000523:psychology; D003936:Diagnosis, Computer-Assisted / Q000379:methods* / Q000706:statistics & numerical data; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D012648:Self Care / Q000379:methods / Q000523:psychology / Q000706:statistics & numerical data