[Clinical parameters of the course of metabolic syndrome in advanced age].
The proposed principles of classification of metabolic syndrome are critically considered, as they do not take into account peculiarities of its clinical course in patients of advanced and senile age. Results of examination are presented of two groups of patients of the cardiological profile, who were long observed under conditions of a departmental outpatient clinic. In the first group, evaluated were the incidence and the degree of severity of symptoms characterizing disturbances in systems of carbohydrate and lipid metabolism, peculiar to metabolic syndrome, as well as the incidence and severity of arterial hypertension and obesity. It has been established that these symptoms are more frequent in various combinations as a picture of the "incomplete" syndrome and have different incidence in the older and younger age groups. Among patients with the "complete" set of characters of the metabolic syndrome there also takes place the statistically significant polymorphism of its clinical manifestations, which allows suggesting effects of mechanism of compensation and mutual aggravation. Peculiarities of manifestations of symptoms of the metabolic syndrome in patients of the elderly group make it possible to identify prognostically favorable and unfavorable forms of the course of the syndrome and, accordingly, to optimize the therapeutic and preventive programs.
Balliuzek
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D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008017:Life Expectancy / Q000639:trends*; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications*; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications*; D009765:Obesity / Q000150:complications*; D012720:Severity of Illness Index