[Study of the effect of aliphatic alcohol on the inclusion interaction of qucertin-cyclodextrin complexes].
The inclusion interaction of qucertin with beta-cyclodextrin and its derivatives was studied by fluorimetry. The formation constants of their inclusion complexes were determined, and the stoichiometry ratio on the formation of the inclusion complexes was determined by equimolar continueous variation method. The effect of aliphatic alcohols with short chains on inclusion process was discussed. The results showed that the inclusion ability of beta-CD and its derivatives was in the order: HP-beta-CD>M-beta-CD>beta-CD. The effect of aliphatic alcohol on complexes was related to the carbon number and volume of alcohol molecules.
Liu
Xiu-ping
XP
Department of Chemistry, Shanxi University, Taiyuan 030006, China.
Zhang
Guo-mei
GM
Yang
Yu
Y
Dong
Chuan
C
Shuang
Shao-min
SM
D000438:Alcohols / Q000737:chemistry* / Q000494:pharmacology; D003505:Cyclodextrins / Q000737:chemistry*; D004347:Drug Interactions; D047392:beta-Cyclodextrins / Q000737:chemistry
D000438:Alcohols; D003505:Cyclodextrins; D047392:beta-Cyclodextrins; C031215:betadex