Job and industry classifications associated with sarcoidosis in A Case-Control Etiologic Study of Sarcoidosis (ACCESS).
OBJECTIVE
To determine whether specific occupations and industries may be associated with sarcoidosis.


METHODS
A Case Control Etiologic Study of Sarcoidosis (ACCESS) obtained occupational and environmental histories on 706 newly diagnosed sarcoidosis cases and matched controls. We used Standard Industrial Classification (SIC) and Standard Occupational Classification (SOC) to assess occupational contributions to sarcoidosis risk.


RESULTS
Univariable analysis identified elevated risk of sarcoidosis for workers with industrial organic dust exposures, especially in Caucasian workers. Workers for suppliers of building materials, hardware, and gardening materials were at an increased risk of sarcoidosis as were educators. Work providing childcare was negatively associated with sarcoidosis risk. Jobs with metal dust or metal fume exposures were negatively associated with sarcoidosis risk, especially in Caucasian workers.


CONCLUSIONS
In this study, we found that exposures in particular occupational settings may contribute to sarcoidosis risk.
Barnard
Juliana
J
Division of Environmental and Occupational Health Sciences, National Jewish Medical and Research Center, 1400 Jackson Street, Denver, CO 80206, USA. barnardj@njc.org
Rose
Cecile
C
Newman
Lee
L
Canner
Martha
M
Martyny
John
J
McCammon
Chuck
C
Bresnitz
Eddy
E
Rossman
Milt
M
Thompson
Bruce
B
Rybicki
Benjamin
B
Weinberger
Steven E
SE
Moller
David R
DR
McLennan
Geoffrey
G
Hunninghake
Gary
G
DePalo
Louis
L
Baughman
Robert P
RP
Iannuzzi
Michael C
MC
Judson
Marc A
MA
Knatterud
Genell L
GL
Teirstein
Alvin S
AS
Yeager
Henry
H
Johns
Carol J
CJ
Rabin
David L
DL
Cherniack
Reuben
R
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007221:Industry; D007587:Job Description; D008297:Male; D008875:Middle Aged; D009790:Occupations; D012307:Risk Factors; D012507:Sarcoidosis / Q000453:epidemiology / Q000209:etiology*