A novel tetrameric short tandem repeat located in the 3' flanking region of the human ABO-secretor gene (FUT2) and association between FUT2 and FUT2/01 loci.
We found a novel polymorphic short tandem repeat (FUT2/01), 3.8 kb downstream of the coding region of FUT2. Seventeen length and 33 sequence variants were identified in 300 individuals representing three major human populations. Africans (Xhosa) and Europeans were characterized by high microvariation, and Japanese were characterized by a simple repeat structure. All exhibited high haplotype diversity.
Pang
Hao
H
Department of Forensic Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.
Soejima
Mikiko
M
Koda
Yoshiro
Y
Kimura
Hiroshi
H
D000017:ABO Blood-Group System / Q000235:genetics*; D000483:Alleles; D020087:Alu Elements / Q000235:genetics; D005647:Fucosyltransferases / Q000235:genetics*; D005787:Gene Frequency; D014644:Genetic Variation; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences
D000017:ABO Blood-Group System; D005647:Fucosyltransferases