[Fibrillary and immunotactoid glomerulonephritis: report of a case and review of the literature].
We describe the case of a 67 year-old female with nephrotic syndrome and rapidly progressive renal failure. The nephropathy was characterized by deposits of randomly oriented fibrils with a diameter of about 18-20 nm on electron microscopy. Immunofluorescence microscopy was performed and there was no staining for immunoglobulins and complement. We diagnosed atypical fibrillary glomerulopathy with absence of immune deposits. The patient developed end-stage renal failure rapidly. We review in the literature new clinical and pathogenetic features related to fibrillary and immunotactoid glomerulopathy.
Vera Méndez
F J
FJ
Servicio de Medicina Interna, Hospital Santa María del Rosell, Cartagena, Murcia. fco-vera@ono.com
Molina Núñez
M
M
Hernández García
M A
MA
García Solano
J
J
D000368:Aged; D005260:Female; D005921:Glomerulonephritis / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology; D009404:Nephrotic Syndrome / Q000473:pathology* / Q000503:physiopathology