title: [Complications of the invasive prenatal diagnostic methods].
abstract: OBJECTIVE
  To provide a literary overview of the complications associated with the invasive prenatal diagnostic methods in the 1st and 2nd trimester of pregnancy.
  
  
  METHODS
  A summarising article.
  
  
  METHODS
  Mother and Child Care Institute, Prague.
  
  
  METHODS
  Compilation of data from professional literature.
  
  
  CONCLUSIONS
  The global trend is characterised by the effort to move prenatal diagnostics into the period of the first trimester. The invasive diagnostic methods of this period - sampling of chorionic villi and timely amniocentesis are subjects of a number of discussions, which deal primarily with their reliability and safety. The main indicator is the evaluation of foetal losses occurring in connection with the action. So far, the safest method is second-trimester amniocentesis; for early diagnostics, the trans-abdominal sampling of chorionic villi is preferred to transcervical one and to early amniocentesis.
authors.affiliation: Ustav pro péci o matku a dito, Praha. kuc.iva@seznam.cz
authors.forename: I
authors.initials: I
authors.lastname: Kucerová
authors.forename: L
authors.initials: L
authors.lastname: Krofta
authors.forename: O
authors.initials: O
authors.lastname: Benegová
mesh_terms: D000649:Amniocentesis / Q000009:adverse effects* / Q000379:methods; D015193:Chorionic Villi Sampling / Q000009:adverse effects* / Q000379:methods; D005260:Female; D006801:Humans; D011247:Pregnancy; D012307:Risk Factors