[Soft tissue calcification in chronic renal failure:prevention and treatment].
Soft tissue calcifications are frequent complication in patients with chronic renal failure. Numerous underlying factors are thought to favor their formation, in particular increased calcium X phosphate product and hyperparathyroidism. Since hyperphosphatemia and /or an increase of the CaXP product are most often involved, a strict control of plasma phosphorus and the avoidance of an increase of plasma calcium should be the goal to be attained permanently in all uremic patients. Various types of drugs have been considered for the treatment of severe soft tissue calcification in uremic patients, including phosphate binder, bisphosphonates and calcitonin.
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Metabolism, Endocrinology and Molecular Medicine Osaka City University Graduate School of Medicine.