title: [A case of liver metastases from cecal cancer successfully treated with fluorouracil and folinic acid (UFT/LV)].
abstract: A 76-year-old man had undergone a right hemicolectomy for cecal cancer. Oral UFT (450 mg/day) administration alone was started 2 months following the operation. From a CT scan of the abdomen performed 3 months postoperatively, he was diagnosed with liver metastasis. Because the liver metastasis had progressed, combination oral administration of UFT+LV was started (UFT 450 mg/day, LV 75 mg/day, 4 weeks of therapy followed by a 1-week treatment break). After 1 cycle, a good partial response of that lesion was achieved. The pulmonary metastasis had almost disappeared to within normal limits. In conclusion, this treatment was very safe and effective.
authors.affiliation: Dept. of Surgery II, Fukushima Medical University.
authors.forename: Motonobu
authors.initials: M
authors.lastname: Saito
authors.forename: Koji
authors.initials: K
authors.lastname: Sekikawa
authors.forename: Shinji
authors.initials: S
authors.lastname: Ohki
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Endo
authors.forename: Takashi
authors.initials: T
authors.lastname: Ohshima
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Fukushima
authors.forename: Masashi
authors.initials: M
authors.lastname: Kanazawa
authors.forename: Seiichi
authors.initials: S
authors.lastname: Takenoshita
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002430:Cecal Neoplasms / Q000473:pathology* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D003082:Colectomy / Q000379:methods; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D005641:Tegafur / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; C096910:UFT(R) drug; D005641:Tegafur; D014498:Uracil; D002955:Leucovorin; D005472:Fluorouracil