A novel approach for the determination of detection limits for metal analysis of environmental water samples.
Despite the widespread use of the USEPA method (U.S. Environmental Protection Agency, 40 CFR 136 Appendix B) for the determination of method detection limit (MDL), criticisms have been raised that the method does not account for measurement bias and outliers that subsequently lead to a common misunderstanding of the requirement for the determination of MDL. This paper demonstrates that it is difficult to follow the USEPA method for verifying the MDL for analysis involving multiple metals and proposes a precision and bias criterion for determining the MDL. A multiple-point fitted profile, based on the correlation between relative standard deviation (RSD) and concentration, is used to derive a robust MDL value. Representative examples of As, Ca, Cr, and Cu are used to illustrate this procedure. A procedure for identifying outliers is also discussed.
Yang
X Jin
XJ
Environmental Forensics and Analytical Science, Department of Environment and Conservation (NSW), Lidcombe 1825, Australia. jin.yang@environment.nsw.gov.au
Low
Gary K-C
GK
Foley
Roy
R
D001151:Arsenic / Q000032:analysis; D002118:Calcium / Q000032:analysis; D002857:Chromium / Q000032:analysis; D003300:Copper / Q000032:analysis; D004784:Environmental Monitoring / Q000379:methods; D008670:Metals / Q000032:analysis*; D012680:Sensitivity and Specificity; D014481:United States; D014484:United States Environmental Protection Agency; D014867:Water / Q000032:analysis* / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000032:analysis*
D008670:Metals; D014874:Water Pollutants, Chemical; D014867:Water; D002857:Chromium; D003300:Copper; D001151:Arsenic; D002118:Calcium