title: Unusual imaging appearances of pancreatic serous cystadenoma: correlation with surgery and pathologic analysis.
abstract: BACKGROUND
  We describe imaging and pathologic features of serous cystadenoma of the pancreas on multislice helical computed tomography CT (MS-CT) and surgical resection.
  
  
  METHODS
  Radiologic and pathologic features were analyzed in five patients. All patients underwent MS-CT and digital subtraction angiography (DSA), and four patients underwent magnetic resonance (MR) imaging. Preoperatively, three cases showed radiologic evidence of mainly solid appearance on MS-CT, and the suspected diagnoses were solid pancreatic tumors (patients 1-3). The other two cases showed radiologic evidence of macrocystic tumor of the pancreas, and the suspected diagnoses were mucinous cystic tumors (cases 4 and 5). All patients underwent surgery, and the diagnosis of serous cystadenoma was confirmed on pathologic examination.
  
  
  RESULTS
  In three cases that showed a solid appearance on MS-CT, a microcystic appearance was identified on microscopic examination, and the tumors were found to be hypervascular lesions on multiphasic contrast-enhanced CT and DSA. In cases 1 and 2, the lesions showed high intensity with internal septation on T2-weighted MR images. In two cases, the tumors were classified as a macrocystic variant of serous cystadenoma, and no mural nodules, papillary projections, or calcifications were seen in the tumors.
  
  
  CONCLUSIONS
  Imaging appearance of serous cystadenoma on MS-CT is various and sometimes indistinguishable from that of solid tumor or mucinous cystic tumors of the pancreas. Imaging findings of hypervascularity and a well-marginated high-intensity lesion with internal septation on T2-weighted MR imaging may be crucial to identify serous cystadenoma that contains no visible cystic compartments on MS-CT.
authors.affiliation: Department of Radiology, Teikyo University School of Medicine, 2-11-1 Itabashi-ku, Tokyo 173-8605, Japan. takesita@med.teikyo-u.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Takeshita
authors.forename: K
authors.initials: K
authors.lastname: Kutomi
authors.forename: K
authors.initials: K
authors.lastname: Takada
authors.forename: H
authors.initials: H
authors.lastname: Kohtake
authors.forename: S
authors.initials: S
authors.lastname: Furui
authors.forename: T
authors.initials: T
authors.lastname: Takada
authors.forename: J
authors.initials: J
authors.lastname: Fukushima
mesh_terms: D000328:Adult; D000368:Aged; D003287:Contrast Media; D018293:Cystadenoma, Serous / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D036542:Tomography, Spiral Computed
chemical_list: D003287:Contrast Media