[Strategies for researches on the interactions between skeletal and vascular tissues].
Osteoporosis and vascular disease are commonly found together in estrogen-deficient and elderly people. The common factors such as estrogen deficiency, abnormalities of vitamin D metabolism, and lipid oxidation have been suggested to contribute to the development of osteoporosis and atherosclerosis. Recent research works on the mechanism of arterial calcification using in vitro models and mouse genetics have unraveled the potential molecular link between osteoporosis and arterial calcification.
Shioi
Atsushi
A
Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine.