Nephrotic syndrome associated with chronic lymphocytic leukaemia.
The simultaneous presentation of B-cell chronic lymphocytic leukaemia and nephrotic syndrome is described. The leukaemia responded to cytotoxic therapy but prednisolone was required to achieve remission of the nephrotic syndrome. The nephrotic syndrome relapsed when the leukaemia again became active and the white cell count rose above 20x10(9)/l, and it remitted again with treatment. The relationship between the two diseases is discussed.
Al-Jehani
Fathi
F
Hematology Department, The Royal Marsden Hospital, London, UK. jehani@doctors.net.uk
Alsousou
Joseph
J
Gover
Pamela
P
D018906:Antineoplastic Agents, Alkylating / Q000008:administration & dosage; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000150:complications* / Q000188:drug therapy; D011239:Prednisolone / Q000008:administration & dosage; D012008:Recurrence; D012074:Remission Induction
D018906:Antineoplastic Agents, Alkylating; D018931:Antineoplastic Agents, Hormonal; D003520:Cyclophosphamide; D011239:Prednisolone