title: [Risk factors of renal failure in the early post-liver transplantation period].
abstract: OBJECTIVE
  To study the risk factors of renal failure in the early post-liver transplantation period.
  
  
  METHODS
  92 consecutive liver transplantation cases were reviewed and a multi-factor analysis of presumed risk factors of early post-transplantation period renal failure was conducted. The factors analyzed were total bilirubin level, prothrombin activity, onset of structural renal disease, onset of gastrointestinal hemorrhage, whether the patient underwent large-volume paracentesis, or underwent plasmapheresis therapy, needed renal replacement therapy, the operation method used, the bleeding volume during operation and the immunosuppressive agents used.
  
  
  RESULTS
  Of the 92 patients, 29 (31.5%) developed acute renal failure (ARF) in the early postoperative period. Multi-factor analysis revealed a high pre-transplantation serum creatinine level and low prothrombin activity as risk factors for development of ARF.
  
  
  CONCLUSIONS
  ARF is a frequent medical complication after liver transplantation. A high pre-transplantation serum creatinine level and low prothrombin activity are risk factors of its development.
authors.affiliation: Department of Hepatobiliary Surgery, People's Hospital of Beijing University, Beijing 100044, China. gandanwk@vip.sina.com
authors.forename: Feng-xue
authors.initials: FX
authors.lastname: Zhu
authors.forename: Chun-jun
authors.initials: CJ
authors.lastname: Liu
authors.forename: Ji-ye
authors.initials: JY
authors.lastname: Zhu
authors.forename: Guang-ming
authors.initials: GM
authors.lastname: Li
authors.forename: Lei
authors.initials: L
authors.lastname: Huang
authors.forename: Dong
authors.initials: D
authors.lastname: Wang
authors.forename: Jie
authors.initials: J
authors.lastname: Gao
authors.forename: Zhi-min
authors.initials: ZM
authors.lastname: Zheng
authors.forename: Xi-sheng
authors.initials: XS
authors.lastname: Leng
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology* / Q000209:etiology; D000293:Adolescent; D000328:Adult; D002681:China / Q000453:epidemiology; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000601:surgery; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011516:Prothrombin / Q000378:metabolism; D012307:Risk Factors
chemical_list: D011516:Prothrombin; D003404:Creatinine