Linezolid use associated with lactic acidosis.
Linezolid is a new synthetic antibiotic with a broad spectrum of activity against virtually all important Gram-positive infections. Lactic acidosis is a well known side-effect of metformin and nucleoside reverse-transcriptase inhibitors. We report a case in which lactic acidosis developed as an adverse effect of linezolid treatment.
Kopterides
Petros
P
Intensive Care Unit, 'Attikon' University Hospital, Athens, Greece. petkop@ath.forthnet.gr
Papadomichelakis
Evangelos
E
Armaganidis
Apostolos
A
D000081:Acetamides / Q000009:adverse effects*; D000140:Acidosis, Lactic / Q000139:chemically induced* / Q000175:diagnosis*; D000368:Aged; D000890:Anti-Infective Agents / Q000009:adverse effects*; D016470:Bacteremia / Q000188:drug therapy*; D003937:Diagnosis, Differential; D006801:Humans; D000069349:Linezolid; D016410:Lymphoma, T-Cell, Cutaneous; D008297:Male; D016106:Methicillin Resistance; D023303:Oxazolidinones / Q000009:adverse effects*; D013203:Staphylococcal Infections / Q000188:drug therapy*
D000081:Acetamides; D000890:Anti-Infective Agents; D023303:Oxazolidinones; D000069349:Linezolid