Structure-function relationship in the tocopherol transfer protein.
The role of specific amino acid residues in mediating the biochemical functions of tocopherol transfer protein (TTP) was investigated using site-directed mutagenesis and functional assays. These findings further current understanding of TTP mechanism of action and its role in human health.
Morley
S
S
Division of Nutritional Sciences, Cornell University, Ithaca, NY, 14853, USA.
Panagabko
C
C
Stocker
A
A
Atkinson
J
J
Manor
D
D
D002352:Carrier Proteins / Q000737:chemistry* / Q000235:genetics / Q000502:physiology*; D006801:Humans; D008099:Liver / Q000737:chemistry; D009154:Mutation; D013329:Structure-Activity Relationship; D014810:Vitamin E / Q000378:metabolism
D002352:Carrier Proteins; C017763:alpha-tocopherol transfer protein; D014810:Vitamin E