[Functional features of acute non-Q-wave myocardial infarction and the influence of pre-hospital treatment with propranalol, heparin and aspirin on the prognosis of the disease].
193 patients with their first non-Q-wave myocardial infarction (NQMI) were examined with the aim of studying the functional features of NQMI and estimate the influence of pre-hospital treatment with propranalol (PP), heparin and aspirin. The study found that patients having NQMI with initial ST segment depression, unlike those with initial ST segment elevation, were characterized by diffuse coronary atherosclerosis, evident diastolic dysfunction and left ventricle (LV) remodeling, progressing with the course of time. Early administration of aspirin, heparin and PP reduced LV remodeling, improved diastolic function and prognosis in patients having NQMI with initial ST segment depression.
Beĭshenkulov
M T
MT
Kudaĭbergenova
N T
NT
Baltabaev
T B
TB
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use*; D001241:Aspirin / Q000008:administration & dosage / Q000627:therapeutic use*; D003627:Data Interpretation, Statistical; D004562:Electrocardiography; D005260:Female; D006493:Heparin / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000503:physiopathology; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D011433:Propranolol / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors; D016277:Ventricular Function, Left; D020257:Ventricular Remodeling
D000319:Adrenergic beta-Antagonists; D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors; D006493:Heparin; D011433:Propranolol; D001241:Aspirin