title: COX-2 inhibitors: exemplars of the drug-safety conundrum.
abstract: Using clinical trials to assess long-term drug safety is problematic; in Australia, simple data linkage based on Medicare numbers may provide useful monitoring information.
authors.forename: Mark R
authors.initials: MR
authors.lastname: Nelson
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Tonkin
authors.forename: Flavia M
authors.initials: FM
authors.lastname: Cicuttini
authors.forename: John J
authors.initials: JJ
authors.lastname: McNeil
mesh_terms: D001315:Australia; D002986:Clinical Trials as Topic / Q000379:methods; D016861:Cyclooxygenase Inhibitors / Q000627:therapeutic use*; D004341:Drug Evaluation / Q000379:methods; D006801:Humans; D009313:National Health Programs; D011358:Product Surveillance, Postmarketing / Q000379:methods*
chemical_list: D016861:Cyclooxygenase Inhibitors