Predominance of afr2 and ral fimbrial genes related to those encoding the K88 and CS31A fimbrial adhesins in enteropathogenic Escherichia coli isolates from rabbits with postweaning diarrhea in Central Europe.
PCR tests designed in these studies identified three rabbit adhesive factor genes among 43 enteropathogenic E. coli (EPEC) strains: afr1 (2 strains), the F4(K88)/CS31A-related afr2 (10 strains), and ral (15 strains). Several EPEC strains (i.e., O153:H7 and O157:H2) lacked these genes but did adhere to HeLa cells and produced attaching and effacing lesions in rabbits.
Dow
Mohamed A
MA
Veterinary Medical Research Institute of the Hungarian Academy of Sciences, 1143 Budapest, Hungaria Str. 21, Budapest, Hungary.
Tóth
István
I
Alexa
Pavel
P
Davies
Michael
M
Malik
Anna
A
Oswald
Eric
E
Nagy
Béla
B
D018830:Adhesins, Escherichia coli / Q000235:genetics*; D000818:Animals; D000942:Antigens, Bacterial / Q000235:genetics*; D001422:Bacterial Adhesion; D003967:Diarrhea / Q000382:microbiology / Q000662:veterinary*; D004926:Escherichia coli / Q000235:genetics*; D019453:Escherichia coli O157 / Q000235:genetics; D029968:Escherichia coli Proteins / Q000235:genetics*; D036781:Fimbriae Proteins / Q000235:genetics*; D010861:Fimbriae, Bacterial / Q000235:genetics*; D006367:HeLa Cells; D006801:Humans; D016133:Polymerase Chain Reaction; D011817:Rabbits / Q000382:microbiology*; D014886:Weaning
D018830:Adhesins, Escherichia coli; D000942:Antigens, Bacterial; D029968:Escherichia coli Proteins; C026888:K88 antigen, E coli; C103954:afr2 protein, E coli; C071730:clpG protein, E coli; D036781:Fimbriae Proteins