title: A new synthesis of 2-substituted pyridines via aluminum chloride induced heteroarylation of arenes and heteroarenes.
abstract: [reaction: see text] We herein report a new synthesis of 2-(hetero)aryl-substituted pyridines via heteroarylation of arenes/heteroarenes through AlCl(3)-induced C-C bond-forming reactions. 2-Halopyridines bearing an electron-withdrawing group were reacted with a number of (hetero)arenes to give 2-aryl/heteroaryl-substituted pyridines in good yields.
authors.affiliation: Chemistry-Discovery Research, Dr. Reddy's Laboratories Ltd., Bollaram Road, Miyapur, Hyderabad 500049, India. manojitpal@drreddys.com
authors.forename: Manojit
authors.initials: M
authors.lastname: Pal
authors.forename: Venkateswara Rao
authors.initials: VR
authors.lastname: Batchu
authors.forename: Indu
authors.initials: I
authors.lastname: Dager
authors.forename: Nalivela Kumara
authors.initials: NK
authors.lastname: Swamy
authors.forename: Srinivas
authors.initials: S
authors.lastname: Padakanti
mesh_terms: D000077410:Aluminum Chloride; D017607:Aluminum Compounds / Q000737:chemistry*; D002712:Chlorides / Q000737:chemistry*; D015394:Molecular Structure; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D017607:Aluminum Compounds; D002712:Chlorides; D011725:Pyridines; D000077410:Aluminum Chloride