title: Synthesis of urea oligomers and their antibacterial activity.
abstract: Facially amphiphilic urea oligomers were successfully prepared in a one-pot reaction by carbonyl diimidazole (CDI) coupling and showed greater antibacterial activity against both Gram-negative Escherichia coli and Gram-positive Bacillus subtilis than MSI-78.
authors.affiliation: Department of Polymer Science and Engineering, University of Massachusetts, 120 Governors Drive, Amherst, MA 01003, USA.
authors.forename: Haizhong
authors.initials: H
authors.lastname: Tang
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Doerksen
authors.forename: Gregory N
authors.initials: GN
authors.lastname: Tew
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects*; D019281:Dimerization; D004925:Escherichia / Q000187:drug effects*; D007093:Imidazoles / Q000737:chemistry; D020128:Inhibitory Concentration 50; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D014508:Urea / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D007093:Imidazoles; C006900:N,N-carbonyldiimidazole; D014508:Urea