title: [Effect of lead on the cardiovascular system].
abstract: Lead is a metal widely spread in the natural environment. It is strongly toxic, particularly to the peripheral and central nervous systems. The toxic influence on the cardiovascular system is most pronounced in case of higher exposures, where myocardium and the renal circulation are affected, in consequence of which secondary arterial hypertension can develop. It seems that lead affects the cardiovascular system mainly by changing the peripheral autonomic nervous system and leading to chronic neuropathy. Chronic exposure, even to low doses of lead, can impair conduction in myocardium. In order to assess those changes thoroughly prospective studies involving newly employed workers with occupational exposure to toxic activity of lead will be necessary.
authors.affiliation: Klinika Kardiologii AM we Wrocławiu. dzysko@wp.pl
authors.forename: Dorota
authors.initials: D
authors.lastname: Zyśko
authors.forename: Ewa
authors.initials: E
authors.lastname: Chlebda
authors.forename: Jacek
authors.initials: J
authors.lastname: Gajek
mesh_terms: D001341:Autonomic Nervous System / Q000503:physiopathology; D002319:Cardiovascular System / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D007854:Lead / Q000009:adverse effects*; D007855:Lead Poisoning / Q000150:complications*; D009206:Myocardium / Q000473:pathology
chemical_list: D007854:Lead