title: Etiology and presentation of acute bacterial meningitis in children at Al-Thawrah Hospital, Sana'a, Yemen.
abstract: BACKGROUND
  This study was carried out to determine the etiology and management outcome of acute bacterial meningitis among children presenting at Al-Thawrah hospital, Sana'a, Yemen.
  
  
  METHODS
  This study was carried out from 01/01/2001 to 23/08/2002. It initially included 77 children of all ages (newborn to 12 years), who attended pediatric emergency with fever, convulsions and altered sensorium. Full medical history. clinical examination and lab investigations were used to diagnose acute bacterial meningitis, and to summarize etiology, presentation and management outcome.
  
  
  RESULTS
  Over this 20 months period only 63 (81.81%) out of 77 suspected children were diagnosed as acute bacterial meningitis (ABM). The most affected age group was 4 months and 3 years. Based on CSF exam; there were 23 with positive findings of CSF analysis (turbid, decrease glucose <40mg.dl, increase protein >80mg.dl and leucocytes neutrophils >5cells.cu.mm), 21 cases were confirmed with CSF culture, while the remaining 19 cases showed normal CSF pictures. The fatality rate was 14.28%. The predominant organism in CSF culture was Klebsiella (33.33%) followed by Haemophilius influenza (23.80%), streptococcal pneumonia (14.28%) then 02 cases each; E-coli, Pseudomonas (09.52%) while with one cases each of tubercles meningitis and staphylococcus aureus.
  
  
  CONCLUSIONS
  Proper knowledge of etiology and presentation of ABM along with timely vaccination can help reduce mortality and morbidity associated with this deadly disease.
authors.affiliation: Department of Peadiatrics, Al-Thawrah Teaching Hospital, Sana'a, Yemen. draks@yemen.net.ye
authors.forename: Abdul Khaliq A
authors.initials: AK
authors.lastname: Sallam
mesh_terms: D000208:Acute Disease; D017677:Age Distribution; D000900:Anti-Bacterial Agents; D002648:Child; D002675:Child, Preschool; D003906:Developing Countries; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006090:Gram-Negative Bacteria / Q000302:isolation & purification*; D006094:Gram-Positive Bacteria / Q000302:isolation & purification*; D006784:Hospitals, Teaching; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D016920:Meningitis, Bacterial / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D010154:Pakistan / Q000453:epidemiology; D018570:Risk Assessment; D012720:Severity of Illness Index; D017678:Sex Distribution; D013129:Spinal Puncture; D015996:Survival Rate
chemical_list: D000900:Anti-Bacterial Agents