title: REM behavior disorder associated with epileptic seizures.
abstract: Reported is the association of REM behavior disorder (RBD) with late-onset, sleep-related, tonic-clonic seizures in two elderly men. In each patient, RBD preceded the onset of seizures by several years. The authors hypothesize that REM sleep disruption may facilitate seizure occurrence.
authors.affiliation: Unit of Sleep Medicine and Epilepsy, Institute of Neurology, IRCCS C. Mondino Foundation, Pavia, Italy. raffaele.manni@mondino.it
authors.forename: Raffaele
authors.initials: R
authors.lastname: Manni
authors.forename: Michele
authors.initials: M
authors.lastname: Terzaghi
mesh_terms: D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use; D001921:Brain / Q000503:physiopathology*; D002998:Clonazepam / Q000627:therapeutic use; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D020187:REM Sleep Behavior Disorder / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology*; D012640:Seizures / Q000150:complications / Q000503:physiopathology; D020182:Sleep Apnea, Central / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology; D012895:Sleep, REM / Q000502:physiology; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants; D002998:Clonazepam