title: Coccidioidomycosis of the male reproductive tract.
abstract: Coccidioides immitis infection of the male reproductive tract is a rare entity that can evade diagnosis and pose a dilemma in management. Initially, patients are often evaluated for malignancy or other infections such as tuberculosis. In the past, surgery was the only management option for C. immitis infection of the male reproductive tract, but azole therapy now provides an adjunct or an alternative. We describe two patients who received azole therapy for C. immitis infection of the male reproductive tract. One received fluconazole for prostatic disease, while one received surgery followed by itraconazole for testicular disease. After 12 months of therapy, both remain asymptomatic and have decreased antibody titers against C. immitis.
authors.affiliation: Department of Infectious Diseases, Wright-Patterson Air Force Base, OH 45433, USA. eric.halsey@wpafb.af.mil
authors.forename: Eric S
authors.initials: ES
authors.lastname: Halsey
authors.forename: Mark S
authors.initials: MS
authors.lastname: Rasnake
authors.forename: Duane R
authors.initials: DR
authors.lastname: Hospenthal
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use*; D003045:Coccidioides / Q000254:growth & development*; D003047:Coccidioidomycosis / Q000188:drug therapy* / Q000469:parasitology; D003168:Complement Fixation Tests; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011469:Prostatic Diseases / Q000188:drug therapy* / Q000469:parasitology*; D013733:Testicular Diseases / Q000188:drug therapy* / Q000469:parasitology*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D015725:Fluconazole