title: Endovascular repair of nontraumatic ruptured thoracic aortic pathologies.
abstract: Endovascular repair of ruptured infrarenal abdominal aortic aneurysms (AAA) is receiving increased attention as the number of experienced users increases. Development of thoracic aortic stent grafts has lagged behind infrarenal advancements because of the reported prevalence of disease. In a few centers, however, the experience in performing thoracic stent graft procedures is quite substantial, such that endovascular therapy has been applied to ruptured thoracic aortic pathologies even though data remain limited and this novel therapy remains controversial. We report our combined experience with endovascular repair of ruptured thoracic aneurysms (RTA) and ruptured thoracic dissections (RTD). One hundred eighty-four thoracic stent graft procedures at the University of North Carolina (UNC) and Union Memorial Hospital (UMH) were reviewed and those patients undergoing RTA or RTD repair from January 1, 2000 to December 31, 2003 identified. Patients having procedures for elective repair or aortic transections were excluded from the analysis. Patient presentation, preoperative condition, procedural variables, mortality, and morbidity were examined. Seventy-four percent of the collective procedures were undertaken in high-risk patients (UNC, 38 of 40; UMH, 99 of 144). Twenty-two patients (8.7%; UNC, n = 6; UMH, n = 16) underwent treatment for either an RTA (n = 11) or an RTD (n = 11). The average age of this cohort was 66.5 +/- 15.6 years and the average aneurysm diameter was 73.1 +/- 31.4 mm. The mean duration of symptoms prior to repair was 103.1 +/- 122 hr, influenced primarily by transport times and device availability. Stent graft exclusion was accomplished in 100% of patients with a procedural mortality of 0%. Commercial Talent devices were used in 19 patients (86.4%) and AneuRx device was used in 1 patient (4.5%). In the remaining two (9.1%) patients hand-made devices constructed of Gianturco stents and Dacron fabric were used because of active hemorrhage and lack of appropriate device sizes. Operative time was 135.5 +/- 48.5 min and was associated with an average blood loss of 242.0 +/- 232.4 cc. Thirty-day mortality was 45.5% (RTA, 27.3%; RTD, 63.6%; p = 0.099). Length of stay in the intensive care unit was 6.1 +/- 7.9 days and the mean hospital stay was 11.7 +/- 10.6 days. Major complications were present in 54.5% of RTA (cardiac, 1; pulmonary, 3; cardiovascular accident, 2; spinal cord ischemia, 2; pulmonary embolism, 1), and 81.2% of RTD (multisystem organ failure, 7; pulmonary, 1; common femoral artery injury, 1) but not statistically different between groups. There were only two late complications (cardiac death, endoleak-Ia, 1) that occurred during the mean follow-up of 12.5 +/- 11.3 (range, 1-32) months. These results indicate that endovascular repair of ruptured thoracic pathologies can be accomplished with an acceptable morbidity and mortality. There were no immediate procedural mortalities and complete exclusion was accomplished in all patients. Most postoperative complications arose from preexisting medical conditions and were not procedure related. The benefit of endovascular repair of ruptured thoracic aortic pathologies is promising.
authors.affiliation: Division of Vascular Surgery, University of North Carolina, Chapel Hill, NC 27599-7212, USA. faberm@med.unc.edu
authors.forename: Mark A
authors.initials: MA
authors.lastname: Farber
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Criado
mesh_terms: D000368:Aged; D000784:Aortic Dissection / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D001019:Aortic Rupture / Q000601:surgery*; D016063:Blood Loss, Surgical; D019917:Blood Vessel Prosthesis Implantation; D015897:Comorbidity; D016208:Databases, Factual; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D011093:Polyethylene Terephthalates; D011183:Postoperative Complications / Q000453:epidemiology / Q000401:mortality; D011474:Prosthesis Design; D015607:Stents; D016019:Survival Analysis; D013997:Time Factors
chemical_list: D011093:Polyethylene Terephthalates