title: Bone implant interface, osteolysis and potential therapies.
authors.affiliation: The Center for Musculoskeletal Research, Department of Orthopaedics, University of Rochester Medical Center, Rochester, NY 14642, USA. Edward_Schwarz@URMC.Rochester.Edu
authors.forename: E M
authors.initials: EM
authors.lastname: Schwarz
authors.forename: R J
authors.initials: RJ
authors.lastname: O'Keefe
authors.forename: R J
authors.initials: RJ
authors.lastname: Looney
mesh_terms: D000818:Animals; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D016025:Bone Transplantation / Q000009:adverse effects* / Q000379:methods*; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000187:drug effects / Q000378:metabolism; D002352:Carrier Proteins / Q000037:antagonists & inhibitors / Q000235:genetics; D004195:Disease Models, Animal; D018450:Disease Progression; D006085:Graft Survival / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D008562:Membrane Glycoproteins / Q000037:antagonists & inhibitors / Q000235:genetics; D051379:Mice; D018345:Mice, Knockout; D010014:Osteolysis / Q000188:drug therapy* / Q000503:physiopathology / Q000517:prevention & control; D053245:RANK Ligand; D053246:Receptor Activator of Nuclear Factor-kappa B; D014057:Tomography, X-Ray Computed / Q000379:methods; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors / Q000378:metabolism
chemical_list: D002352:Carrier Proteins; D008562:Membrane Glycoproteins; D053245:RANK Ligand; D053246:Receptor Activator of Nuclear Factor-kappa B; C505686:TNFRSF11A protein, human; C505688:TNFSF11 protein, human; C505687:Tnfrsf11a protein, mouse; C505689:Tnfsf11 protein, mouse; D014409:Tumor Necrosis Factor-alpha