title: Clinical results of Perftoran application: present and future.
abstract: Clinical experience of Perftoran (commercial drug of low concentrated perfluorocheminal emulsion) applications is presented in some statistical data and in brief analysis of clinical trials and following clinical studies described in the Russian scientific literature. Observed data allow us to suppose that Perftoran facilitates oxygen delivery together with remaining red blood cells at blood replacements and will have more wider area for application than just a blood substitute. Its infusion alleviates symptoms of ischemia at different types of occlusion vessels disease, improves grafting in plastic surgery, diminishes inflammation and prevents rejection of transplants, activates detoxication functions of liver, inhibits retro-virus infection development. Local PF applications is able to accelerate wounds and ulcers healing.
authors.affiliation: Institute of Theoretical and Experimental Biophysics of RAS, Moscow Region, Russia. emaevsky@iteb.ru
authors.forename: Eugene
authors.initials: E
authors.lastname: Maevsky
authors.forename: Genrih
authors.initials: G
authors.lastname: Ivanitsky
authors.forename: Ludmila
authors.initials: L
authors.lastname: Bogdanova
authors.forename: Olga
authors.initials: O
authors.lastname: Axenova
authors.forename: Natalia
authors.initials: N
authors.lastname: Karmen
authors.forename: Eugene
authors.initials: E
authors.lastname: Zhiburt
authors.forename: Raisa
authors.initials: R
authors.lastname: Senina
authors.forename: Sergey
authors.initials: S
authors.lastname: Pushkin
authors.forename: Igor
authors.initials: I
authors.lastname: Maslennikov
authors.forename: Andrey
authors.initials: A
authors.lastname: Orlov
authors.forename: Irina
authors.initials: I
authors.lastname: Marinicheva
mesh_terms: D001802:Blood Substitutes / Q000008:administration & dosage*; D001803:Blood Transfusion / Q000639:trends; D002986:Clinical Trials as Topic; D005466:Fluorocarbons / Q000008:administration & dosage*; D006801:Humans; D010100:Oxygen / Q000378:metabolism*
chemical_list: D001802:Blood Substitutes; D005466:Fluorocarbons; C063334:perftoran; D010100:Oxygen