Human papillomaviruses and skin cancer.
Cutaneous epidermodysplasia verruciformis (EV)-associated human papillomaviruses (HPVs) are found frequently in skin cancers especially in immunosuppressed people. They are also detectable in the normal skin and hair follicles of a proportion of individuals who have no immune defect. The available evidence to link HPVs causally with skin carcinogenesis is not conclusive, but includes epidemiological, molecular and immunological studies.
Sterling
Jane C
JC
Departments of Medicine and Pathology, University of Cambridge, UK. jcs12@mole.bio.cam.ac.uk
D004819:Epidermodysplasia Verruciformis / Q000821:virology; D018859:Hair Follicle / Q000821:virology; D006801:Humans; D027383:Papillomaviridae / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000150:complications* / Q000821:virology; D012867:Skin / Q000821:virology; D012878:Skin Neoplasms / Q000821:virology*