Antifungal peptides: Origin, activity, and therapeutic potential.
Antifungal peptides have been identified in a wide range of life forms which include plants, mammals, and microorganisms. Their structures are as varied as their antifungal properties. Semisynthetic and fully synthetic analogs have been developed from a few of these natural peptides that are superior to the parent compound. A few of these peptides hold promise in combating fungal infections and have entered clinical trials.
De Luca
A J
AJ
Southern Regional Research Center, USDA, ARS, New Orleans, LA, USA. adelucca@commserver.srrc.usda.gov
Walsh
T J
TJ