Total mandibular reconstruction for massive osteolysis of the mandible (Gorham-Stout syndrome).
Massive osteolysis (Gorham-Stout syndrome) is a rare condition of unknown aetiology that is thought to result from a localised endothelial proliferation of lymphatic vessels resulting in destruction and absorption of bone. The diagnosis of Gorham-Stout syndrome can be made only after first excluding osteolysis from infection, inflammation, endocrine disease, and cancer. The syndrome is rarely seen in the facial skeleton and has a variable prognosis. Many treatments have been advocated but only surgery and radiotherapy have had some success. We present a case of massive osteolysis of the entire mandible, which was reconstructed with a free vascularised fibular graft and bilateral prosthetic replacements of the temporomandibular (TMJ) joints. Four years later the fibular graft had been absorbed requiring further reconstruction with another fibula graft.
Paley
M D
MD
Department of Oral and Maxillofacial Surgery, Glan Clwyd Hospital, Bodelwyddan, Rhyl, North Wales LL18 5UJ, UK. martin@paley10.freeserve.co.uk
Lloyd
C J
CJ
Penfold
C N
CN
D016025:Bone Transplantation / Q000379:methods; D005260:Female; D005360:Fibula / Q000637:transplantation; D006801:Humans; D007595:Joint Prosthesis; D008334:Mandible / Q000601:surgery*; D008336:Mandibular Diseases / Q000601:surgery*; D008875:Middle Aged; D019647:Oral Surgical Procedures; D010015:Osteolysis, Essential / Q000601:surgery*; D012008:Recurrence; D012086:Reoperation; D013577:Syndrome; D013704:Temporomandibular Joint / Q000601:surgery*