Effects of chicken extract on antioxidative status and liver protection under oxidative stress.
Chicken extract contains carnosine and anserine, both of which possess some antioxidant abilities. The objective of this study was to investigate the protective effects of chicken extract in male Sprague-Dawley (SD) rats under induced oxidative stress. Carbon tetrachloride was used as the oxidative stress inducer. Glutamic-oxalacetatic transaminase (GOT), glutamic-pyruvic transaminase (GPT), total antioxidant status (TAS), thiobarbituric-reactive substances (TBARS), iron content, and the activities of antioxidant enzymes were determined. We concluded that under oxidative stress, the intake of chicken extract was helpful in promoting the activities of antioxidant enzymes and in protecting the liver from oxidative damage.
Peng
Hsiang-Chi
HC
School of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan 110.
Lin
Shyh-Hsiang
SH
D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D000861:Anserine / Q000032:analysis; D000975:Antioxidants / Q000032:analysis*; D001219:Aspartate Aminotransferases / Q000097:blood; D001835:Body Weight; D002251:Carbon Tetrachloride / Q000494:pharmacology; D002336:Carnosine / Q000032:analysis; D002374:Catalase / Q000097:blood; D002645:Chickens; D004032:Diet; D005290:Ferric Compounds / Q000097:blood; D005296:Ferrous Compounds / Q000097:blood; D005979:Glutathione Peroxidase / Q000097:blood; D005980:Glutathione Reductase / Q000097:blood; D008107:Liver Diseases / Q000517:prevention & control*; D008297:Male; D018384:Oxidative Stress; D011202:Poultry Products; D051381:Rats; D017207:Rats, Sprague-Dawley; D013482:Superoxide Dismutase / Q000097:blood; D017392:Thiobarbituric Acid Reactive Substances / Q000032:analysis
D000975:Antioxidants; D005290:Ferric Compounds; D005296:Ferrous Compounds; D017392:Thiobarbituric Acid Reactive Substances; D002336:Carnosine; D002251:Carbon Tetrachloride; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D005980:Glutathione Reductase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000861:Anserine