title: Tacrolimus ointment for the treatment of severe facial plaque psoriasis.
abstract: Recently, tacrolimus ointment has proved to be effective and well tolerated in patients with facial psoriasis. A few months ago we had the opportunity to treat a patient with tacrolimus ointment who had severe and recalcitrant plaque psoriasis of the face. This present case illustrates the impressive improvement of facial plaque psoriasis following 5 months of treatment with tacrolimus 0.1% ointment twice a day. Significant improvement of facial plaque psoriasis was seen after 1 month and complete clearance after 5 months of therapy. Based on the available literature and illustrated by the present case we may conclude that tacrolimus ointment 0.1% can be recommended as a first-line treatment for facial psoriasis.
authors.affiliation: Department of Dermatology, University Medical Centre St Radboud, PO Box 9101, 6500 HB Nijmegen, the Netherlands. i.kroft@derma.umcn.nl
authors.forename: E B M
authors.initials: EB
authors.lastname: Kroft
authors.forename: A
authors.initials: A
authors.lastname: Erceg
authors.forename: K
authors.initials: K
authors.lastname: Maimets
authors.forename: W
authors.initials: W
authors.lastname: Vissers
authors.forename: P G M
authors.initials: PG
authors.lastname: van der Valk
authors.forename: P C M
authors.initials: PC
authors.lastname: van de Kerkhof
mesh_terms: D000287:Administration, Topical; D005148:Facial Dermatoses / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009824:Ointments; D011565:Psoriasis / Q000188:drug therapy*; D016559:Tacrolimus / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D007166:Immunosuppressive Agents; D009824:Ointments; D016559:Tacrolimus