title: Necrobiosis lipoidica.
abstract: A 68-year-old woman presented with a 3-year history of asymptomatic, yellow-brown plaques on the lower extremities with trauma-related superficial ulcers. A biopsy specimen was consistent with necrobiosis lipoidica. Necrobiosis lipoidica is a chronic granulomatous dermatitis that is associated with diabetes mellitus; however, its pathogenesis remains unclear. Topical glucocorticoids are first-line therapy; however, no treatment has proven efficacy in double-blind, placebo-controlled studies.
authors.affiliation: Ronald O. Perelman Department of Dermatology, New York University, USA.
authors.forename: Sue Ann
authors.initials: SA
authors.lastname: Wee
authors.forename: Paul
authors.initials: P
authors.lastname: Possick
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D009335:Necrobiosis Lipoidica / Q000473:pathology*