Liver transplantation as definitive treatment for a factor V Leiden mutation.
Liver transplantation (LT) was achieved for factor V Leiden-induced thrombophilia in a neonate with hepatic veno-occlusive disease. Initial LT was performed with a liver segment removed from a child with primary oxalosis. Four months later, a second, definitive LT was performed. The child remains well without recurrent thrombosis.
Dunn
Stephen P
SP
Division of Solid Organ Transplantation, Nemours Biomedical Research, Nemours Children's Clinic-Wilmington, Alfred I. duPont Hospital for Children, Delaware, USA.
Tsai
Anthony
A
Griffin
Gregory
G
Toth
Stephen
S
Casas-Melley
Adela T
AT
Falkenstein
Kathleen P
KP
Marando
Cindy A
CA
Krueger
Leslie J
LJ
D005165:Factor V / Q000235:genetics*; D006504:Hepatic Veno-Occlusive Disease / Q000235:genetics / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D017093:Liver Failure / Q000235:genetics / Q000601:surgery; D016031:Liver Transplantation; D008297:Male; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA / Q000379:methods; D019851:Thrombophilia / Q000235:genetics / Q000601:surgery*
C095381:factor V Leiden; D005165:Factor V