title: The transcriptional signature of vitamin E.
abstract: To investigate the ability of RRR-alpha-tocopherol to regulate gene expression, we interrogated RNA samples from treated cultured cells with Affymetrix oligonucleutodie arrays. We find that vitamin E potently regulates the expression of ca. 230 genes, functioning in metabolism, cell-cycle progression, and transcriptional regulation.
authors.affiliation: Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA.
authors.forename: Amy
authors.initials: A
authors.lastname: Johnson
authors.forename: Danny
authors.initials: D
authors.lastname: Manor
mesh_terms: D002453:Cell Cycle / Q000235:genetics; D005786:Gene Expression Regulation / Q000187:drug effects*; D006801:Humans; D008660:Metabolism / Q000235:genetics; D020411:Oligonucleotide Array Sequence Analysis; D014158:Transcription, Genetic / Q000187:drug effects; D024502:alpha-Tocopherol / Q000494:pharmacology*
chemical_list: D024502:alpha-Tocopherol