title: No baseline for blood pressure in ordinary life: another case of transient chronome alterations.
abstract: Half-hourly systolic (S) and diastolic (D) blood pressure (BP) and heart rate (HR) monitoring with gaps demonstrates transient elevations of unknown origin of the chronome (time structure)-adjusted mean, the MESOR, M, of BP, and of the circadian double amplitude of BP of TS, a clinically healthy-appearing engineering student who was 27 years of age at the start of the study. An assessment of large and small arterial vessel elasticity was in keeping with no detection of functional or structural alteration in her vasculature. The recovery of normality in BP endpoints at the time of this report is speculatively associated with a weight loss of 40 pounds and the formation of a friendship by correspondence. Whatever the underlying mechanisms of a long series of abnormal records may be, a 'baseline' can include weeklong spans of abnormality and is best replaced by comparisons with chronomic reference values.
authors.affiliation: Department of Electrical Engineering and Computer Science, University of Minnesota, Minneapolis, MN, USA.
authors.forename: Tina
authors.initials: T
authors.lastname: Sarabandi
authors.forename: Jay
authors.initials: J
authors.lastname: Cohn
authors.forename: Germaine
authors.initials: G
authors.lastname: Cornélissen
authors.forename: Franz
authors.initials: F
authors.lastname: Halberg
authors.forename: George
authors.initials: G
authors.lastname: Katinas
authors.forename: James
authors.initials: J
authors.lastname: Holte
authors.forename: Othild
authors.initials: O
authors.lastname: Schwartzkopff
authors.forename: Kuniaki
authors.initials: K
authors.lastname: Otsuka
mesh_terms: D000203:Activities of Daily Living / Q000145:classification* / Q000523:psychology; D000328:Adult; D000367:Age Factors; D001683:Biological Clocks / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D001795:Blood Pressure Determination / Q000379:methods; D001835:Body Weight / Q000502:physiology; D002909:Chronobiology Phenomena / Q000502:physiology; D005260:Female; D005783:Gender Identity; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007564:Japan; D012016:Reference Values; D015203:Reproducibility of Results; D013997:Time Factors