Clerodane diterpenoids from Pulicaria wightiana.
Five clerodane diterpenoids have been isolated from the aerial parts of Pulicaria wightiana along with 3'5,6-trihydroxy-3,4',7-trimethoxyflavone and 2-methyl-5-hydroxy-chroman-4-one. The structures and stereochemistry of the compounds were established from spectral (mainly 1D and 2D NMR) studies. The last two compounds were not reported earlier from this plant. The antibacterial activity of the diterpenoids were studied.
Das
Biswanath
B
Indian Institute of Chemical Technology, Organic Chemistry-1, Tarnaka, Hyderabad 500 007, India. biswanthdas@yahoo.com
Ravinder Reddy
M
M
Ramu
R
R
Ravindranath
N
N
Harish
H
H
Ramakrishna
K V S
KV
Koteswar Rao
Y
Y
Harakishore
K
K
Murthy
U S N
US
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D019659:Asteraceae / Q000737:chemistry*; D001419:Bacteria / Q000187:drug effects; D002839:Chromans / Q000302:isolation & purification; D045785:Diterpenes, Clerodane / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D047309:Flavones / Q000302:isolation & purification; D015394:Molecular Structure
C501184:2-methyl-5-hydroxy-chroman-4-one; C501183:3',5,6-trihydroxy-3,4',7-trimethoxyflavone; D000900:Anti-Bacterial Agents; D002839:Chromans; D045785:Diterpenes, Clerodane; D047309:Flavones