title: Interaction between individual protein components of the GerA and GerB nutrient receptors that trigger germination of Bacillus subtilis spores.
abstract: Germination of Bacillus subtilis spores via the GerA nutrient receptor was suppressed by GerAC lacking the diacylglycerylated cysteine essential for receptor function. Overexpression of the C protein of the GerB nutrient receptor also suppressed the function of both the GerA receptor and a variant GerB receptor, GerB*. These findings suggest that GerAC and GerBC interact with their respective A and B proteins in GerA or GerB receptors and that GerBC potentially interacts with GerAA-GerAB. However, GerAC did not appear to interact with GerBA-GerBB.
authors.affiliation: Department of Molecular, Microbial and Structural Biology, University of Connecticut Health Center, Farmington, CT 06030-3305, USA. setlow@nso2.uchc.edu
authors.forename: Takao
authors.initials: T
authors.lastname: Igarashi
authors.forename: Peter
authors.initials: P
authors.lastname: Setlow
mesh_terms: D000595:Amino Acid Sequence; D001412:Bacillus subtilis / Q000235:genetics* / Q000378:metabolism* / Q000502:physiology; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D004075:Diglycerides / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D013171:Spores, Bacterial / Q000235:genetics / Q000378:metabolism
chemical_list: D001426:Bacterial Proteins; D004075:Diglycerides; D008565:Membrane Proteins