REM behavior disorder associated with epileptic seizures.
Reported is the association of REM behavior disorder (RBD) with late-onset, sleep-related, tonic-clonic seizures in two elderly men. In each patient, RBD preceded the onset of seizures by several years. The authors hypothesize that REM sleep disruption may facilitate seizure occurrence.
Manni
Raffaele
R
Unit of Sleep Medicine and Epilepsy, Institute of Neurology, IRCCS C. Mondino Foundation, Pavia, Italy. raffaele.manni@mondino.it
Terzaghi
Michele
M
D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use; D001921:Brain / Q000503:physiopathology*; D002998:Clonazepam / Q000627:therapeutic use; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D020187:REM Sleep Behavior Disorder / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology*; D012640:Seizures / Q000150:complications / Q000503:physiopathology; D020182:Sleep Apnea, Central / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology; D012895:Sleep, REM / Q000502:physiology; D016896:Treatment Outcome
D000927:Anticonvulsants; D002998:Clonazepam