[Diagnostic and prognostic value of determining serum levels of cytokines and antibodies to basic myeloprotein in chronic manganese intoxication].
Findings are that progression of chronic manganese intoxication comes along with development of humoral immune response to antibodies of myelinic coating of nerve fibers. That is expressed by increased occurrence of reliable titers of antibodies to basic myeloprotein G and increased serum IL-6 level. The authors suggest using determination of serum antibodies to myeloprotein G and IL-1, IL-6 to specify severity of chronic manganese intoxication.
Riabova
O I
OI
Davydova
N I
NI
Kalashnikova
A A
AA
D000328:Adult; D000906:Antibodies / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D002908:Chronic Disease; D016207:Cytokines / Q000097:blood*; D018450:Disease Progression; D006801:Humans; D007375:Interleukin-1 / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D020149:Manganese Poisoning / Q000097:blood / Q000175:diagnosis*; D008875:Middle Aged; D004676:Myelin Basic Protein / Q000097:blood / Q000276:immunology*; D009186:Myelin Sheath / Q000276:immunology; D009784:Occupational Diseases / Q000097:blood / Q000175:diagnosis*; D014896:Welding
D000906:Antibodies; D015415:Biomarkers; D016207:Cytokines; D007375:Interleukin-1; D015850:Interleukin-6; D004676:Myelin Basic Protein