[Inverted urothelial papilloma: report of 151 cases].
OBJECTIVE
To investigate the clinical features, pathology, diagnosis and treatment of inverted urothelial papilloma.


METHODS
A total of 151 cases of urothelial inverted papilloma were analysed retrospectively. Of the cases, 134 were male and 17 were female, with a mean age of 54 years old. Most patients complained of painless gross hematuria. The diagnosis could be established mainly by ultrasonic, intravenous urography, retrograde pyelography, cystoscope and pathology. Among them, 7 cases who had the papilloma at upper urinary tract underwent nephroureterectomy except one. One hundred and forty-four cases had the papilloma at low urinary tract, with 124 treated by transurethral bladder tumor resection (TURBT), among which 11 cases accompanying benign prostatic hyperplasia were treated by transurethral prostatic resection, 3 by transurethral resection of prostatic urethral tumor, 15 by partial cystectomy, 2 by total cystectomy.


RESULTS
One hundred and eighteen cases were followed up 1 year to 12.5 years (mean 6.3 years). Intravesical recurrence was found in 5 cases. Of them 2 cases developed malignance in 8 and 30 months postoperatively, and 1 case underwent total cystectomy.


CONCLUSIONS
Inverted urothelial papilloma is a benign tumor, which appears male predominant. Most of the lesions are found in the bladder. TURBT is the preferred treatment choice for inverted papilloma of the bladder. Although this disease has a good prognosis, regular follow-up observations are necessary.
Wan
Qun
Q
Department of Urology, First Affiliated Hospital, Medical College of Zhejiang University, Hangzhou 310003, China. hz_wanqun@163.com
Luo
Jin-dan
JD
Cai
Song-liang
SL
Shen
Bo-hua
BH
Zhao
Wei-ping
WP
Zhang
Zhi-gen
ZG
Xie
Li-ping
LP
Shen
Zhou-jun
ZJ
D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D018308:Papilloma, Inverted / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D014571:Urologic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*