[Blood compatibility of block copolymer membranes of poly(benzyl L-glutamate)/poly(ethylene glycol)].
The blood compatibility of block copolymer membranes of poly(benzyl L-glutamate)/poly(ethylene glycol) and the effect of on the blood compatibility of copolymer were evaluated by the clotting time test, the platelet adhesion and deformation test, and the protein adsorption test. The results showed that in terms of blood compatibility, homopolymer was better than glass and silicone, copolymer was better than homopolymer, and the more the PEG in the copolymer, the better the blood compatibility.
Wang
Qinmei
Q
Artificial Heart Lab, First Affiliated Hospital, Zhongshan University, Guangzhou 510080, China. qimeiwang1205@hotmail.com
Teng
Wei
W
Pan
Shirong
S
Zhang
Jingxia
J
D001672:Biocompatible Materials; D004337:Drug Carriers; D008422:Materials Testing; D010973:Platelet Adhesiveness / Q000187:drug effects*; D011092:Polyethylene Glycols / Q000138:chemical synthesis / Q000737:chemistry*; D011099:Polyglutamic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry
D001672:Biocompatible Materials; D004337:Drug Carriers; D011108:Polymers; C003172:poly-gamma-benzyl-L-glutamate; D011099:Polyglutamic Acid; D011092:Polyethylene Glycols