Esters of cephalosporins part IX. New method of isolation of cefetamet pivoxil.
A new method of isolation of cefetamet pivoxil, which results in higher purity and higher yield than according to the known methods, was worked out. The new method depends on ability to the adsorption on acidic active carbon of total amount of this antibiotic together with only a small amount of impurities. During two-step elution all impurities were washed out in the first step and in the next step pure cefetamet pivoxil was eluated by another solvent.
Oszczapowicz
Irena
I
Institute of Biotechnology and Antibiotics, 5 Staroścńska Str., Warsaw, Poland.
Teodorczyk
Anna
A
Tejchman
Bozena
B
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification*; D015296:Ceftizoxime / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification*; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer
D000900:Anti-Bacterial Agents; D015296:Ceftizoxime; C047445:cefetamet pivoxyl