[Enhancement of bone formation by PTH and its effect on bone mass and strength].
Intermittent administration of low dose PTH has strong anabolic effect on bone by enhancing bone formation, resulting in increase of mechanical strength. Although newly formed bone with less mineralization and increased cortical porosity induced by high bone turnover may have adverse effect on bone strength, PTH is expected to be a new drug for the treatment of osteoporosis.
Hirano
Toru
T
Division of Orthopaeic Surgery, Department of Regenerative and Transplant medicine, Niigata University Graduate School of Medical and Dental Science.
Endo
Naoto
N