Increase of antibody titer against Leucocytozoon caulleryi by oral administration of recombinant R7 antigen.
In this study, we examined oral administration with recombinant R7 (rR7) antigen expressed in Escherichia coli using chicken leucocytozoonosis subunit vaccine (LV)-vaccinated and unvaccinated chickens. Only LV-vaccinated chickens showed re-induction of anti-second-generation schizont (2GS) antibody. Also, LV-vaccinated chickens whose anti-2GS antibody titer was middle-level showed increases of the antibody titer compared to vaccinated-control chickens (P>0.01, >0.05) after oral administration with rR7 antigen.
Ito
Akira
A
Research Center for Biologicals, The Kitasato Institute, Kitamoto 364-0026, Saitama, Japan.
Gotanda
Tohru
T
Kobayashi
Shigeki
S
Kume
Katsumi
K
Sugimoto
Chihiro
C
Matsumura
Takeshi
T
D000284:Administration, Oral; D000818:Animals; D000913:Antibodies, Protozoan / Q000276:immunology*; D000953:Antigens, Protozoan / Q000008:administration & dosage / Q000276:immunology*; D002645:Chickens / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D016787:Haemosporida / Q000276:immunology*; D013997:Time Factors
D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan