[The mechanism which calcitonin activates vitamin D].
Calcitropic hormones, such as calcitonin and vitamin D, are one of the most common drugs used in the treatment of osteoporosis. Recently, three enzymes involved in vitamin D metabolism (25-hydroxylase, 24-hydroxylase, 1alpha-hydroxylase) were cloned and enabled us to analyze the vitamin D metabolism at a molecular level. We summarize the mechanism which CT activates vitamin D.
Hosogane
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Department of Biochemistry, School of Dentistry, Showa University.
Shinki
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