title: [Percutaneous closure of a perimembraneous ventricular septal defect: the first 4 patients in The Netherlands].
abstract: In four female patients, aged 30, 10, 8 and 2 years and 9 months (the latter with Down's syndrome), all with a perimembranous ventricular septal defect (VSD), percutaneous closure of the VSD was carried out using an Amplatzer endoprosthesis. These were the first 4 patients to undergo this procedure in The Netherlands. In 3 of the patients the procedure was without complications and complete occlusion of the defects was achieved. The last patient developed a left anterior hemiblock after implantation of the device and one week later an intermittent second degree atrioventricular block was detected, for which a pacemaker was implanted. A few days later the atrioventricular conduction time returned to normal. There was complete occlusion of the defect. Percutaneous closure of a perimembranous VSD using an Amplatzer prosthesis is a promising technique with good short-term results. In a selected group of patients this new technique can replace surgical treatment.
authors.affiliation: Kinderhartcentrum, Universitair Medisch Centrum St Radboud, Postbus gIoi, 6500 HB Nijmegen. a.vanoort@cukz.umcn.nl
authors.forename: A M
authors.initials: AM
authors.lastname: van Oort
authors.forename: H R
authors.initials: HR
authors.lastname: Gehlmann
authors.forename: N A
authors.initials: NA
authors.lastname: Blom
mesh_terms: D000328:Adult; D006348:Cardiac Surgical Procedures / Q000295:instrumentation* / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000601:surgery*; D006801:Humans; D007223:Infant; D019060:Minimally Invasive Surgical Procedures; D019736:Prostheses and Implants; D016896:Treatment Outcome