title: The relationship between the MRI features of mild osteoarthritis in the patellofemoral and tibiofemoral compartments of the knee.
abstract: The aim of this work was to demonstrate the relationship between osteoarthritic changes seen on magnetic resonance (MR) images of the patellofemoral (PF) or tibiofemoral (TF) compartments in patients with mild osteoarthritis (OA) of the knee. MR images of the knee were obtained in 105 sib pairs (210 patients) who had been diagnosed with OA at multiple joints. Entry criteria included that the degree of OA in the knee examined should be between a Kellgren and Lawrence score of 2 or 3. MR images were analyzed for the presence of cartilaginous lesions, bone marrow edema (BME) and meniscal tears. The relationship between findings in the medial and lateral aspects of the PF and TF compartments was examined. The number of cartilaginous defects on either side of the PF compartment correlated positively with number of cartilaginous defects in the ipsilateral TF compartment (odds ratio, OR, 55, confidence interval, CI, 7.8-382). The number of cartilaginous defects in the PF compartment correlated positively with ipsilateral meniscal tears (OR 3.7, CI 1.0-14) and ipsilateral PF BME (OR 17, CI 3.8-72). Cartilaginous defects in the TF compartment correlated positively with ipsilateral meniscal tears (OR 9.8, CI 2.5-38) and ipsilateral TF BME (OR 120, CI 6.5-2,221). Osteoarthritic defects lateralize or medialize in the PF and TF compartments of the knee in patients with mild OA.
authors.affiliation: Department of Radiology, C2-S, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands. p.r.kornaat@lumc.nl
authors.forename: Peter R
authors.initials: PR
authors.lastname: Kornaat
authors.forename: Iain
authors.initials: I
authors.lastname: Watt
authors.forename: Naghmeh
authors.initials: N
authors.lastname: Riyazi
authors.forename: Margreet
authors.initials: M
authors.lastname: Kloppenburg
authors.forename: Johan L
authors.initials: JL
authors.lastname: Bloem
mesh_terms: D005260:Female; D005270:Femur Head / Q000473:pathology; D006801:Humans; D007719:Knee Joint / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000473:pathology*; D010329:Patella / Q000473:pathology; D013977:Tibia / Q000473:pathology