[The drug treatment for bone resorption in the oral area].
The bone resorption in the oral area can be divided into the inflammatory and the metabolic bone resorption. In this review, we show a possibility for drug treatment in oral area, focusing on the drug development of TNF antagonist which inhibits the actions of both TNF-alpha and RANKL; the cytokines which have a critical role in the inflammatory bone resorption.
Aoki
Kazuhiro
K
Section of Pharmacology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University.
Ohya
Keiichi
K