Periodicity in collision-induced and remote-bond activation of alkali metal ions attached to polyether ionophores.
The collision-induced dissociation of lasalocid and monensin A bound to alkali metal cations has been investigated using electrospray MS/MS. The binding affinity for the metal cations, as measured with collision-induced dissociation, was found to depend on their ionic radius, decreasing with increasing radius. Monensin A was observed to have a greater binding affinity for alkali metal cations than lasalocid acid.
Francis
Gregory J
GJ
Department of Chemistry and Centre for Research in Mass Spectrometry, York University, Toronto, ON, M3J 13P, Canada.
Forbes
Matthew
M
Volmer
Dietrich A
DA
Bohme
Diethard K
DK
D000818:Animals; D001667:Binding, Competitive; D002412:Cations; D004350:Drug Residues / Q000737:chemistry*; D005506:Food Contamination; D007476:Ionophores / Q000737:chemistry*; D007832:Lasalocid / Q000737:chemistry; D008672:Metals, Alkali / Q000737:chemistry*; D008985:Monensin / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D013057:Spectrum Analysis
D002412:Cations; D007476:Ionophores; D008672:Metals, Alkali; D008985:Monensin; D007832:Lasalocid