[Kidney transplantation and bone].
Osteoporosis, renal osteodystrophy and osteoarthropathy derived from hemodialysis associated amyloidosis are three major bone diseases after the kidney transplantation. Osteoporosis that is induced by steroid administration is an inevitable side effect and develops more frequently in the elderly recipients. After the recovery of renal function due to grafted kidney, secondary hyperparathyroidism usually improves and the serum level of PTH-intact downs to the almost normal range. However, the patients who have tertiary hyperparathyroidism are unable to show the enough lowering of PTH-intact. In these cases, renal osteodystrophy progresses even though kidney grafts have fine renal function. Osteoarthropathy derived from hemodialysis associated amyloidosis reveals distinct clinical courses depending to the types of diseases. Some of them improve and the remained ones become worse. After the kidney transplantation we must keep to concern for the bone condition of grafted patients.
Nishi
Shinichi
S
Blood Purification Center, Niigata University Hospital.
Gejyo
Fumitake
F