A solitary laryngeal neurofibroma ina pediatric patient.
A neurofibroma of the larynx is a rare disease that usually involves the arytenoids and the aryepiglottic fold. Pediatric patients with a laryngeal neurofibroma often present with progressive dyspnea. A definitive diagnosis of a laryngeal neurofibroma is based on the histopathologic demonstration of the characteristic spindle cells, and a positive result in immunohistochemical staining for S-100 protein. Tumor excision of laryngeal neurofibromas by an external approach was formerly common. We present a case of a solitary laryngeal neurofibroma in a 4-year-old child that was completely excised using direct laryngoscopy and a CO2 laser. There has been no recurrence after a follow-up of 4 years. For pediatric patients with an isolated laryngeal neurofibroma, endoscopic surgery provides an alternative approach due to its safety, effectiveness, and minimal invasiveness.
Chen
Yi-Wei
YW
Department of Otolaryngology, Chang Gung Memorial Hospital, Taipei.
Fang
Tuan-Jen
TJ
Li
Hsueh-Yu
HY
D002675:Child, Preschool; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D007828:Laryngoscopy; D007830:Larynx / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D009455:Neurofibroma / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D009418:S100 Proteins / Q000032:analysis
D009418:S100 Proteins