[Recurrent disease in renal cell carcinoma. "Local recurrence" after kidney-sparing and radical resection].
Locally recurrent renal cell carcinoma (RCC) is 0-10% after nephron-sparing surgery, 2.5-4% after thermoablative interventions and 2-3% after (radical) nephrectomy. Risk-factors are: sporadic or hereditary origin, tumor size, multifocality, histologic phenotype and incomplete resection. To date, there are no significant differences in the incidence of locally recurrent tumors independently of whether open or laparoscopic techniques were preferred. Caution still has to be taken with the use of alternative tools for minimally invasive tumor ablation.Finally, no statistically proven standard therapy exists that would clearly provide a superior outcome for patients with an isolated local recurrence. However, meta-analyses strongly support the performance of a resection of the recurrence as the primary working principal.
Löhr
M
M
Urologische Klinik, Klinikum Darmstadt.
Rohde
D
D
D002292:Carcinoma, Renal Cell / Q000601:surgery*; D006801:Humans; D007680:Kidney Neoplasms / Q000601:surgery*; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D009364:Neoplasm Recurrence, Local / Q000628:therapy*; D009392:Nephrectomy / Q000379:methods*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D016879:Salvage Therapy / Q000379:methods*; D013727:Terminal Care / Q000379:methods; D016896:Treatment Outcome