Dioxin toxicity and chloracne in the Ukraine.
Dioxin toxicity can lead to severe cutaneous and systemic disease. The poisoning of Ukrainian President Viktor Yushchenko dramatically illustrates the damage dioxin can inflict. The hallmark of dioxin toxicity is chloracne and should alert the clinician to this diagnosis, which can be confirmed by blood tests. Olestra, a non-absorbable, non-digestible fat substitute is a promising new treatment to lower systemic dioxin levels.
Sterling
J Barton
JB
Laser and Skin Surgery Center of Indiana, Carmel 46032, USA.
Hanke
C William
CW
D000152:Acne Vulgaris / Q000139:chemically induced*; D004147:Dioxins / Q000633:toxicity*; D006801:Humans; D000072317:Polychlorinated Dibenzodioxins / Q000097:blood / Q000633:toxicity*
D004147:Dioxins; D000072317:Polychlorinated Dibenzodioxins