title: Transient neurologic deficit after acetazolamide challenge for computed tomography perfusion imaging.
abstract: A case of transient neurologic deficit associated with the acetazolamide challenge conducted in conjunction with dynamic enhanced computed tomography (CT) perfusion imaging for the evaluation of cerebral hemodynamic impairment is reported in a patient with known cerebrovascular steno-occlusive disease. Combining the acetazolamide challenge with dynamic CT perfusion provides a rapid and widely available technique to assess cerebrovascular reactivity; however, one must be cognizant of this serious potential adverse response.
authors.affiliation: Department of Radiology, University of Michigan, Ann Arbor, MI 48109-0030, USA. vrchoksi@med.umich.edu
authors.forename: Vaishali
authors.initials: V
authors.lastname: Choksi
authors.forename: Marion
authors.initials: M
authors.lastname: Hughes
authors.forename: Linda
authors.initials: L
authors.lastname: Selwa
authors.forename: Ellen
authors.initials: E
authors.lastname: Hoeffner
mesh_terms: D000086:Acetazolamide / Q000009:adverse effects*; D001783:Blood Flow Velocity / Q000187:drug effects; D002257:Carbonic Anhydrase Inhibitors / Q000009:adverse effects*; D016893:Carotid Stenosis / Q000000981:diagnostic imaging*; D002531:Cerebellum / Q000098:blood supply; D002533:Cerebral Angiography; D004244:Dizziness / Q000139:chemically induced; D004292:Dominance, Cerebral / Q000187:drug effects; D005260:Female; D006801:Humans; D006987:Hypesthesia / Q000139:chemically induced; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D007275:Injections, Intravenous; D002546:Ischemic Attack, Transient / Q000139:chemically induced* / Q000000981:diagnostic imaging; D008875:Middle Aged; D009055:Mouth / Q000294:innervation; D009460:Neurologic Examination / Q000187:drug effects; D012039:Regional Blood Flow / Q000187:drug effects / Q000502:physiology; D014057:Tomography, X-Ray Computed
chemical_list: D002257:Carbonic Anhydrase Inhibitors; D000086:Acetazolamide