Malaria epidemic and drug resistance, Djibouti.
Analysis of Plasmodium falciparum isolates collected before, during, and after a 1999 malaria epidemic in Djibouti shows that, despite a high prevalence of resistance to chloroquine, the epidemic cannot be attributed to a sudden increase in drug resistance of local parasite populations.
Rogier
Christophe
C
IMTSSA-IFR48, BP46, Parc du Pharo, 13998 Marseille-Armees, France. christophe.rogier@wanadoo.fr
Pradines
Bruno
B
Bogreau
H
H
Koeck
Jean-Louis
JL
Kamil
Mohamed-Ali
MA
Mercereau-Puijalon
Odile
O
D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D016054:DNA, Protozoan / Q000737:chemistry / Q000235:genetics; D004196:Disease Outbreaks; D015730:Djibouti / Q000453:epidemiology; D004351:Drug Resistance / Q000235:genetics; D014644:Genetic Variation; D006239:Haplotypes; D006801:Humans; D016778:Malaria, Falciparum / Q000097:blood / Q000188:drug therapy / Q000453:epidemiology* / Q000469:parasitology*; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000302:isolation & purification; D017354:Point Mutation; D016133:Polymerase Chain Reaction
D000962:Antimalarials; D016054:DNA, Protozoan