Metabolic alterations and cardiovascular risk factors in the polycystic ovary syndrome.
Available literature indicates that polycystic ovary syndrome (PCOS) represents a condition with a high prevalence of the metabolic syndrome, a greater and precocious appearance of glucose intolerance states, including type 2 diabetes mellitus, and a potentially greater risk for cardiovascular diseases. With respect to metabolic disorders, however, there is also emerging evidence that they are more prevalent in PCOS rather than in the general population, and that there are regional differences in the world, depending on lifestyle and other environmental factors. This evidence should be taken into consideration in future strategies focusing on prevention of metabolic and cardiovascular disorders in PCOS, not only on treatment of infertility and signs of androgen excess.
Pasquali
R
R
Department of Internal Medicine, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy. renato.pasquali@unibo.it
Patton
L
L
Pagotto
U
U
Gambineri
A
A
D002318:Cardiovascular Diseases / Q000453:epidemiology*; D015897:Comorbidity; D005260:Female; D018149:Glucose Intolerance / Q000453:epidemiology* / Q000378:metabolism*; D006801:Humans; D011085:Polycystic Ovary Syndrome / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors