title: Left ventricular function in children with sleep-disordered breathing.
abstract: Severe obstructive sleep apnea in children leads to congestive heart failure. We studied the early changes in left ventricular function across a range of severity of the disorder. A dose-dependent decrease in diastolic function with increased severity of obstructive apnea was demonstrated.
authors.affiliation: Department of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA. aminr@chmcc.org
authors.forename: Raouf S
authors.initials: RS
authors.lastname: Amin
authors.forename: Thomas R
authors.initials: TR
authors.lastname: Kimball
authors.forename: Maninder
authors.initials: M
authors.lastname: Kalra
authors.forename: Jenny L
authors.initials: JL
authors.lastname: Jeffries
authors.forename: John L
authors.initials: JL
authors.lastname: Carroll
authors.forename: Judy A
authors.initials: JA
authors.lastname: Bean
authors.forename: Sandra A
authors.initials: SA
authors.lastname: Witt
authors.forename: Betty J
authors.initials: BJ
authors.lastname: Glascock
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Daniels
mesh_terms: D000293:Adolescent; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D002306:Cardiac Volume / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D003971:Diastole / Q000502:physiology; D004452:Echocardiography; D005260:Female; D006333:Heart Failure / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000503:physiopathology; D009200:Myocardial Contraction / Q000502:physiology; D010100:Oxygen / Q000097:blood; D017286:Polysomnography; D012016:Reference Values; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis* / Q000503:physiopathology; D013599:Systole / Q000502:physiology; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis* / Q000503:physiopathology; D016277:Ventricular Function, Left / Q000502:physiology
chemical_list: D010100:Oxygen