title: Homoflavonoids from Ophioglossum petiolatum.
abstract: Six homoflavonoids, ophioglonin (1), ophioglonin 7-O-beta-D-glucopyranoside (2), ophioglonol (3), ophioglonol prenyl ether (4), ophioglonol 4'-O-beta-D-glucopyranoside (5), and isoophioglonin 7-O-beta-D-glucopyranoside (6), together with five known compounds, quercetin, luteolin, kaempferol, 3,5,7,3',4'-pentahydroxy-8-prenylflavone, and quercetin 3-O-methyl ether, were isolated from Ophioglossum petiolatum. Their structures were elucidated by analysis of spectroscopic data and chemical evidence. Compounds 1 and quercetin 3-O-methyl ether showed slight anti-HBV surface antigen activity at 25 microM.
authors.affiliation: National Research Institute of Chinese Medicine, Taipei 112, Taiwan. yllin@cma23.nricm.edu.tw
authors.forename: Yun-Lian
authors.initials: YL
authors.lastname: Lin
authors.forename: Chien-Chang
authors.initials: CC
authors.lastname: Shen
authors.forename: Yeh-Jeng
authors.initials: YJ
authors.lastname: Huang
authors.forename: Ying-Ying
authors.initials: YY
authors.lastname: Chang
mesh_terms: D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006514:Hepatitis B Surface Antigens / Q000187:drug effects; D044949:Kaempferols / Q000302:isolation & purification; D047311:Luteolin / Q000302:isolation & purification; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D011794:Quercetin / Q000302:isolation & purification; D013624:Taiwan
chemical_list: D005419:Flavonoids; D006514:Hepatitis B Surface Antigens; D044949:Kaempferols; C006552:kaempferol; D011794:Quercetin; D047311:Luteolin