Presacral carcinoid tumour. Review of the literature and report of a clinically malignant case.
Carcinoid tumours arising in the presacral region are extremely rare and they are usually benign. We report the case of a 37-year-old black man with a clinically malignant carcinoid tumour (well differentiated endocrine carcinoma) occurring in a sacrococcygeal teratoma and already metastasised to pelvic nodes, liver and bone at the time of the initial diagnosis. Such an aggressive behaviour of the presacral carcinoid tumours has never been described. The derivation of these tumours from hindgut rests with reference to embryological development of the tailgut cysts is discussed.
Luong
T V
TV
Department of Pathology and Laboratory Medicine, Section of Pathological Anatomy, University of Parma, via Gramsci 14, Parma I-43100, Italy.
Salvagni
S
S
Bordi
C
C
D000328:Adult; D001859:Bone Neoplasms / Q000556:secondary; D002276:Carcinoid Tumor / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008297:Male; D017773:Pelvic Floor / Q000000981:diagnostic imaging / Q000473:pathology; D010386:Pelvic Neoplasms / Q000556:secondary; D010751:Phosphopyruvate Hydratase / Q000032:analysis; D012445:Sacrococcygeal Region; D016708:Synaptophysin / Q000032:analysis; D014057:Tomography, X-Ray Computed
D016708:Synaptophysin; D010751:Phosphopyruvate Hydratase