Age scope of high-risk population for esophageal cancer in Ci county.
OBJECTIVE
To define the age scope of high-risk population for esophageal cancer (EC) in Ci county.


METHODS
The results of endoscopic examination of 2 013 subjects, cytological screening of 16 763 persons and records of 9 265 patients with EC were analyzed by Ridit methods, the standard age group was 45-49 year group.


RESULTS
The average age of patients with moderate esophageal epithelium dysplasia by endoscopic examination was 53.5 years, of severe esophageal epithelium dysplasia, 51.4 years, early EC, 55.6 years. The average age of stage one severe epithelium dysplasia (SEEDI) by cytological screening was 51.2 years, of stage two severe epithelium esophageal dysplasia (SEED II) 51.6 years, of advanced EC 61.7 years. In the group of 40-year olds, the value of Ridit by pathological diagnosis was 0.46, 95% CI, 0.45-0.47, that by cytological diagnosis was 0.45, 95% CI, 0.43-0.47. As the age increased at five-year intervals, the value of Ridit increased significantly.


CONCLUSIONS
In Ci county of a high incidence area of EC, the age definition of high-risk population should be above 45 years.
Chen
Zhi-Feng
ZF
Hebei Cancer Institute, Shijiazhuang 050011, Hebei Province, China. czf@xinhuanet.com
Hou
Jun
J
Ding
Zhen-Wei
ZW
Guo
Cui-Lan
CL
Qiao
Cui-Yun
CY
Song
Guo-Hui
GH
Li
Shao-Sen
SS
Zhang
Jian-Hui
JH
He
Yu-Tong
YT
D000328:Adult; D017677:Age Distribution; D000368:Aged; D002681:China / Q000453:epidemiology; D004938:Esophageal Neoplasms / Q000453:epidemiology*; D006801:Humans; D008875:Middle Aged; D011230:Precancerous Conditions / Q000453:epidemiology*; D012307:Risk Factors