title: Pilocytic astrocytoma of the adult--clinical features, radiological features and management.
abstract: Pilocytic astrocytoma is a histological subtype of astrocytoma classically located in the cerebellum of children and young adults. Cases occurring over the age of 30 years are rare and have not been classified in terms of their clinical features and management. Suitable cases were identified using diagnostic coding and by reviewing a neuropathology database. Casenotes and neuroradiology were reviewed retrospectively. Ten cases were identified over a 6 year period with an incidence of 0.49 cases per million population per year. Tumours were equally distributed between the supra- and infra-tentorial spaces. The most common symptom was headache occurring in 90%. No patient suffered seizures. Total macroscopic treatment remains the treatment of choice. Pilocytic astrocytoma of the adult is a rare tumour with a favourable prognosis.
authors.affiliation: Department of Neurosurgery, King's College Hospital, Denmark Hill, London SE5 9RS, UK. david.bell@bsuhunhs.uk
authors.forename: D
authors.initials: D
authors.lastname: Bell
authors.forename: B P
authors.initials: BP
authors.lastname: Chitnavis
authors.forename: S
authors.initials: S
authors.lastname: Al-Sarraj
authors.forename: S
authors.initials: S
authors.lastname: Connor
authors.forename: M M
authors.initials: MM
authors.lastname: Sharr
authors.forename: R W
authors.initials: RW
authors.lastname: Gullan
mesh_terms: D000328:Adult; D000368:Aged; D001254:Astrocytoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed