title: Risk factors for secondary dilatation of the aorta after acute type A aortic dissection.
abstract: OBJECTIVE
  Prompt diagnosis of subsequent dilatation of the dissected aorta is crucial to reduce late mortality in these patients. This study focuses on risk factors for dilatation of the aorta after type A aortic dissection (AADA) affecting a normal-sized or slightly dilated aorta.
  
  
  METHODS
  Overall 531 CT scans were analysed. Patients were included in the study if at least 3 CT scans were available after operative repair. 64 patients (59.8%) out of 107 patients full-field the inclusion criteria. Volumetric analyses of the aorta were performed. Patients were divided in 3 groups: group A included 26 patients (40.6%) without progression of the aortic diameter, group 2, 27 patients (42.2%) with slight progression and group 3, 11 patients (17.2%) with important progression, requiring surgery in 9 patients (81.8%). Risk-factors for progression of the aortic size were analysed and compared between the groups.
  
  
  RESULTS
  Patients from group 3 were younger 57.7+/-13.4 vs. 61.9+/-11.6 in group 1 (P<0.05) and were more frequent female (45.4 vs. 23.1%; P<0.05). Dissection of the supraaortic branches (100 vs. 80.8%; P<0.05), the presence of preoperative cerebral, visceral or peripheral malperfusion (54.6 vs. 26.9%; P<0.05) and contrast enhancement in the false lumen during the follow-up (72.7 vs. 57.7%; P=0.07) were additional risk factors for late aortic dilatation in these patients.
  
  
  CONCLUSIONS
  Acute type A aortic dissection in younger patients, involving the supraaortic branches and/or combined with malperfusion syndrome favour secondary dilatation. A close follow-up is mandatory to prevent acute complications of the diseased downstream aorta following repair of a AADA.
authors.affiliation: Department of Cardiovascular Surgery, University Hospital, 3010 Berne, Switzerland. franzimmer@yahoo.de
authors.forename: Franz F
authors.initials: FF
authors.lastname: Immer
authors.forename: Urs
authors.initials: U
authors.lastname: Hagen
authors.forename: Pascal A
authors.initials: PA
authors.lastname: Berdat
authors.forename: Friedrich S
authors.initials: FS
authors.lastname: Eckstein
authors.forename: Thierry P
authors.initials: TP
authors.lastname: Carrel
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000784:Aortic Dissection / Q000601:surgery*; D001011:Aorta / Q000473:pathology*; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D004108:Dilatation, Pathologic / Q000000981:diagnostic imaging / Q000209:etiology; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D011183:Postoperative Complications; D012086:Reoperation; D012307:Risk Factors; D014057:Tomography, X-Ray Computed