title: Rosai-Dorfman disease mimicking a sphenoid wing meningioma.
abstract: A 40-year-old male presented with a single generalized tonic-clonic seizure. MRI revealed an enhancing, dural-based, left lateral sphenoid wing lesion suggestive of a meningioma. At microsurgical excision, the lesion was firm and relatively avascular. The histopathological report revealed S-100 positive histiocytic proliferation with lymphophagocytosis (emperipolesis) characteristic of the Rosai-Dorfman disease. The case and its management are discussed.
authors.affiliation: Department of Surgical Neurology, The Neurosciences Center, The Indraprastha Apollo Hospital, Sarita Vihar, New Delhi 110-044, India.
authors.forename: Manish S
authors.initials: MS
authors.lastname: Sharma
authors.forename: Michelle De
authors.initials: MD
authors.lastname: Padua
authors.forename: Ajaya N
authors.initials: AN
authors.lastname: Jha
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D015618:Histiocytosis, Sinus / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology*; D008579:Meningioma / Q000473:pathology*; D013100:Sphenoid Bone