title: [Three cases of multiple colorectal liver metastases responding to hepatic arterial infusion chemotherapy undergoing liver resection].
abstract: We encountered three cases of multiple liver metastases of colorectal cancer treated with hepatic resection after hepatic arterial infusion. Case 1: A 55-year-old female underwent sigmoidectomy for sigmoid colon cancer and six liver metastases. After responding postoperatively to hepatic arterial infusion chemotherapy (HIA), she underwent resection of liver metastases. Case 2: A 66-year-old man underwent colectomy and hepatic resection for cecal colon cancer and liver metastasis. Multiple liver metastases appeared six months after the operation. HIA resulted in a complete response. Liver metastases recurred twice and liver resection was performed each time. Case 3: A 52-year-old female underwent partial resection of colon and liver for ascending colon cancer and multiple liver metastases. After she responded postoperatively to HIA and systemic chemotherapy, the patient underwent resection of liver metastases. Case 1 has lung metastases at this writing. The other two patients are alive and well, and have been free from recurrence as of 4 years after operation.
authors.affiliation: Dept. of Surgery, Niigataken Koseiren Kariwagun General Hospital.
authors.forename: Kumiko
authors.initials: K
authors.lastname: Kobayashi
authors.forename: Kyo
authors.initials: K
authors.lastname: Ueki
authors.forename: Dai
authors.initials: D
authors.lastname: Ishizuka
authors.forename: Ryuji
authors.initials: R
authors.lastname: Wakakuwa
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003082:Colectomy; D012809:Colon, Sigmoid / Q000601:surgery; D003110:Colonic Neoplasms / Q000473:pathology* / Q000601:surgery; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D015251:Epirubicin / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006498:Hepatectomy; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D002955:Leucovorin / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012811:Sigmoid Neoplasms / Q000473:pathology / Q000601:surgery
chemical_list: D015251:Epirubicin; D004317:Doxorubicin; D002955:Leucovorin; D005472:Fluorouracil