Mammography of ductal carcinoma in situ of the breast: review of 909 cases with radiographic-pathologic correlations.
We retrospectively analysed mammographies of 909 ductal carcinoma in situ (DCIS) (1980-1999) and compared our results to those of literature. Microcalcifications were present in 75% of the cases, and soft-tissue abnormalities in 27% cases with association with calcifications in 14% of cases. Palpable masses were found in 12% of the cases and nipple discharge was present in 12% of the cases. The radiographic-pathologic correlation allowed to suspect the DCIS "aggressiveness" on radiologic signs. Granular, linear, branching and/or galactophoric topography of the microcalcifications were correlated with necrosis, grade 3, comedocarcinoma type. A number of microcalcifications higher than 20 was correlated with necrosis and grade 3. Mammographic size was correlated to histologic size. Masses were correlated with grade 1. A diagnosis strategy can be proposed with a multidisciplinar approach.
Barreau
Béatrice
B
Department of Radiology, Institut Bergonié, Regional Cancer Center, 229, cours de l'Argonne, 33076 Bordeaux Cedex, France. barreau@bergonie.org
de Mascarel
Isabelle
I
Feuga
Caroline
C
MacGrogan
Gaétan
G
Dilhuydy
Marie-Hélène
MH
Picot
Véronique
V
Dilhuydy
Jean-Marie
JM
de Lara
Christine Tunon
CT
Bussières
Emmanuel
E
Schreer
I
I
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D002114:Calcinosis / Q000000981:diagnostic imaging; D002278:Carcinoma in Situ / Q000000981:diagnostic imaging* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging* / Q000473:pathology; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D012189:Retrospective Studies