Unusual cardiac papillary fibroelastoma in the right ventricular outflow tract.
Cardiac papillary fibroelastoma (CPF) is the second most common benign neoplasm of the heart. This study describes the case of an 81-year-old man who was admitted to the hospital for severe vertigo and in whom a tumor at the right ventricular outflow tract (RVOT) was identified incidentally during echocardiography. The CPF was excised smoothly following the confirmation of its position by computed tomography. The comprehensive pathologic findings of CPF were reviewed. Detailed immunohistochemical analyses of CD34 and factor VIII-related antigen were performed on the covering endocardial cells. The unique chondroid metaplasia of fibrous tissue in this CPF has never been reported. This work is the first to present an unusual CPF at the RVOT with reactive process of fibrous connective tissue.
Chang
Yu-Sheng
YS
Division of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital, Chang Gung University, 199 Tun-Hwa North Road, Taipei 105, Taiwan.
Chu
Pao-Hsien
PH
Jung
Shih-Ming
SM
Lim
Kun-Eng
KE
Chu
Jaw-Ji
JJ
Hsueh
Chuen
C
Lee
Ying-Shiung
YS
D000368:Aged; D000369:Aged, 80 and over; D018952:Antigens, CD34 / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D004452:Echocardiography; D042783:Endothelial Cells / Q000378:metabolism / Q000473:pathology; D005350:Fibroma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006338:Heart Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006352:Heart Ventricles / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D010210:Papillary Muscles / Q000378:metabolism / Q000473:pathology*; D016896:Treatment Outcome; D014841:von Willebrand Factor / Q000378:metabolism
D018952:Antigens, CD34; D015415:Biomarkers; D014841:von Willebrand Factor