title: [Superficial mycoses: comparative study between type 2 diabetic patients and a non-diabetic control group].
abstract: Superficial mycoses are considered to affect more frequently patients with type 2 diabetes mellitus (DM-2), specially onychomycosis and Tinea pedis. The purpose of this study was to compare the dermatophytoses, candidiasis and Pitiriasis versicolor frequency between 40 patients with DM-2 and 40 healthy persons of either sex, 40 years old or more. Clinical, metabolic, mycologic and inmunologic studies against Candida albicans, were carried out. Both diabetics 75% (30/40) and controls 65% (26/40) presented a high frequency of superficial mycoses (no significant difference p = 0.329). Pitiriasis versicolor was not detected in diabetic patients. They presented Tinea unguium, concomitant with Tinea pedis, with a higher frequency. The predominant dermatophyte was Trichophyton rubrum 18/23 (78%) in diabetics and 8/16 (50%) in non diabetics. Candida was isolated as commensal from oral mucous: 23/40 (58%) in diabetics and 21/40 (52%) in non diabetics (serotipo A was the more frequent), and from onychomycosis: 11/40 (28%) in diabetics and 12/40 (30%) in non diabetics. The immunological response was the same in both groups: celular 100%, humoral 20%. No statistical correlation among superficial mycoses, blood glucose level, glycosylated hemoglobin values or the time suffering the disease was observed. The high susceptibility to dermatophytes and Candida sp. infection showed to be associated with age and no with the diabetic type 2 condition in those patients.
authors.affiliation: Centro de Investigaciones Biomédicas, Universidad Nacional Experimental "Francisco de Miranda", Coro. humbria_leyla@hotmail.com
authors.forename: Leila
authors.initials: L
authors.lastname: García-Humbría
authors.forename: Nicole
authors.initials: N
authors.lastname: Richard-Yegres
authors.forename: Maigualida
authors.initials: M
authors.lastname: Pérez-Blanco
authors.forename: Francisco
authors.initials: F
authors.lastname: Yegres
authors.forename: Mireya
authors.initials: M
authors.lastname: Mendoza
authors.forename: Arnaldo
authors.initials: A
authors.lastname: Acosta
authors.forename: Rosaura
authors.initials: R
authors.lastname: Hernández
authors.forename: Eluz
authors.initials: E
authors.lastname: Zárraga
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002177:Candidiasis / Q000453:epidemiology; D016009:Chi-Square Distribution; D003881:Dermatomycoses / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D014009:Onychomycosis / Q000453:epidemiology; D015995:Prevalence; D014010:Tinea Versicolor / Q000453:epidemiology; D014687:Venezuela / Q000453:epidemiology