Clinicopathological survey of 101 canine mammary gland tumors: differences between small-breed dogs and others.
Clinicopathological features of mammary gland tumors (MGTs) in 101 dogs were evaluated retrospectively. The incidence of histological malignancy in 60 small- and 41 other-breed dogs were 25% and 58.5%, respectively. In 82 epithelial MGTs, small-sized tumors (< 3 cm) or non-invasive tumors were predominant in small breeds. In multivariate survival analysis, small breed (p=0.048) and lower stage of tumor cell invasion (p=0.006) were significantly associated with longer survival time. These results suggest that the incidence of histological or biological malignancy in MGTs is lower in small-breed dogs than in others.
Itoh
Teruo
T
Division of Animal Medical Research, Miyazaki 881-0012, Japan.
Uchida
Kazuyuki
K
Ishikawa
Kenichi
K
Kushima
Kiyotaka
K
Kushima
Eiko
E
Tamada
Hiroyoshi
H
Moritake
Takashi
T
Nakao
Hiroyuki
H
Shii
Hiroki
H
D000818:Animals; D049628:Body Size; D004283:Dog Diseases / Q000401:mortality* / Q000473:pathology; D004285:Dogs; D007564:Japan; D015674:Mammary Neoplasms, Animal / Q000401:mortality* / Q000473:pathology; D012189:Retrospective Studies; D013045:Species Specificity; D016019:Survival Analysis