title: Toward on-chip X-ray analysis.
abstract: The possibility of performing chemical analysis and structure determinations with the use of X-rays in a microfluidic chip environment is explored. Externally generated radiation, radioisotope irradiation and on-chip generated X-rays were considered as excitation means for the performance of sample analysis with the techniques of X-ray fluorescence and diffraction. The absorption properties of chip-building materials by different radiation sources are reviewed and data on absorption coefficients calculated, upon which recommendations for optimisations with the use of various X-ray sources may be made. The capabilities and limitations of on-chip X-ray analysis are placed in perspective by preliminary experimental results of diffraction, fluorescence and on-chip X-ray generation experiments.
authors.affiliation: Universidad Simón Bolívar, Apartado 89000, Caracas 1080A, Venezuela. egreaves@usb.ve
authors.forename: Eduardo D
authors.initials: ED
authors.lastname: Greaves
authors.forename: Andreas
authors.initials: A
authors.lastname: Manz
mesh_terms: D000042:Absorption; D004867:Equipment Design / Q000639:trends; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods; D008962:Models, Theoretical; D013052:Spectrometry, X-Ray Emission / Q000295:instrumentation; D013499:Surface Properties; D014961:X-Ray Diffraction / Q000295:instrumentation; D014965:X-Rays