Corticosteroids in the management of the paediatric epilepsies.
Corticosteroids (predominantly prednisolone and hydrocortisone) and adrenocorticotropic hormone (ACTH) have been used in the treatment of the epilepsies for over 50 years. Over the past 30 years most reports have focused on epilepsy syndromes and epileptic encephalopathies resistant to treatment with the more conventional anticonvulsant and antiepileptic drugs (AEDs) and specifically West syndrome. There has been relatively little attention on the role of corticosteroids in treating other epilepsies.
Gupta
R
R
The Roald Dahl EEG Unit, Department of Neurology, Royal Liverpool Children's NHS Trust (Alder Hey), Liverpool, UK.
Appleton
R
R
D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D000927:Anticonvulsants / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D004827:Epilepsy / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D013036:Spasms, Infantile / Q000188:drug therapy; D013577:Syndrome
D000305:Adrenal Cortex Hormones; D000927:Anticonvulsants