title: The clinical significance and management of microleakage. Part one.
abstract: This research reviews relevant articles related to microleakage from 1966 to the present. The review discusses what the sensation of microleakage is clinically; how dentin permeability is related to microleakage; how the quality of dentin affects permeability and microleakage; what the effects of bacterial infiltration from microleakage can be, as well as the body's defenses against bacterial infiltration within the tooth complex; how caries and microleakage are related; and how various materials and procedures can be used to limit microleakage.
authors.affiliation: Department of Restorative Sciences, Division of Operative Dentistry, University of Minnesota School of Dentistry, Minneapolis, Minnesota, USA. larso004@umn.edu
authors.forename: Thomas D
authors.initials: TD
authors.lastname: Larson
mesh_terms: D001421:Bacteria, Anaerobic / Q000472:pathogenicity; D003731:Dental Caries / Q000209:etiology / Q000382:microbiology*; D003763:Dental Leakage / Q000150:complications*; D003804:Dentin / Q000382:microbiology; D003806:Dentin Permeability; D019234:Dentinal Fluid / Q000502:physiology; D006801:Humans