title: Meningitis due to Enterobacter aerogenes subsequent to resection of an acoustic neuroma and abdominal fat graft to the mastoid.
abstract: Meningitis is an uncommon complication of neurosurgical procedures, with an incidence of 1.1% to 2.5%. Although unusual, the frequency of nosocomial Gram-negative meningitis appears to be increasing. Gram-negative meningitis has been documented following disruption of the dura-arachnoid barrier secondary to trauma or surgery. The association of Gram-negative bacillary meningitis with neurosurgical procedures was first reported in the 1940's. Wolff et al. described the association between Enterobacter species and post-neurosurgical infection. More recently, risk factors for nosocomial Enterobacter meningitis have been characterized by Parodi et al. Adipose graft, as an independent risk factor has not yet been reported. A patient with acoustic neuroma resection, who developed bacterial meningitis from an abdominal fat pad graft to a mastoidectomy bed is described. A brief overview was made of post-neurosurgical Gram-negative meningitis.
authors.affiliation: Department of Medicine, Section of Infectious Diseases, West Virginia University, Morgantown, WV26505, USA. fkhan@hsc.wvu.edu
authors.forename: Fida A
authors.initials: FA
authors.lastname: Khan
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation*; D021902:Enterobacter aerogenes / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D008416:Mastoid / Q000601:surgery; D016920:Meningitis, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000601:surgery*; D011183:Postoperative Complications / Q000382:microbiology*; D012307:Risk Factors