title: Strictures of the terminal bile duct--who profits from the surgery?
abstract: BACKGROUND
  Elucidation of the etiology of terminal bile duct strictures is oftentimes challenging. In choosing the optimal treatment method, a multidisciplinary approach is necessary.
  
  
  OBJECTIVE
  To demonstrate the advantages and indications of surgical management, 153 patients with terminal bile duct strictures were retrospectively analysed. All patients had been treated during a period of eight years (1st January 1995 - 31st December 2002) in same department. The principal datas studied were surgical morbidity, thirty-days' mortality rates and recurrence of jaundice.
  
  
  RESULTS
  During a period of eight years, 153 patients (100%) underwent laparotomy. Radical surgery (duodenopancreatectomy) was performed in 79 patients (51.6%), while 74 others (48.4%) benefited from bypass procedures. Postoperative morbidity reached 13.1%; nine patients (5.9%) died within the thirty days of surgery. Recurrence of jaundice was observed in three patients (1.9%).
  
  
  CONCLUSIONS
  Surgical management of terminal bile duct strictures is indicated in most patients with benign strictures, strictures of unknown origin and with malignant strictures, where the patients are in a reasonably satisfactory clinical condition. The surgical approach provides the potential advantage to obtain a definite histological diagnosiscare and to remove the tumour in many patients. Patients with non resectable tumours could benefit from bypass procedures ensuring long-term and effective drainage of the bile.
authors.affiliation: Department of Surgery University Hospital Motol, Prague, Czech Republic. jan.leffler@lfmotol.cuni.cz
authors.forename: J
authors.initials: J
authors.lastname: Leffler
authors.forename: J
authors.initials: J
authors.lastname: Simsa
authors.forename: P
authors.initials: P
authors.lastname: Poloucek
authors.forename: T
authors.initials: T
authors.lastname: Krejci
authors.forename: P
authors.initials: P
authors.lastname: Grabec
mesh_terms: D002779:Cholestasis / Q000150:complications / Q000601:surgery*; D003251:Constriction, Pathologic; D006801:Humans; D041781:Jaundice, Obstructive / Q000209:etiology / Q000601:surgery*; D012189:Retrospective Studies