title: Isolated congenital histiocytosis in the palpebral conjunctiva in a newborn.
abstract: OBJECTIVE
  To report a rare case of congenital histiocytosis in a newborn without skin involvement.
  
  
  METHODS
  Interventional case-report.
  
  
  METHODS
  A full-term baby presented with a mass over the palpebral conjunctiva of his left upper lid. Ophthalmic examination was otherwise normal, and the baby was healthy. There were no skin lesions.
  
  
  RESULTS
  The lesion was completely removed surgically. Pathologic examination demonstrated a cellular infiltrate composed of eosinophils and histiocytes. Immunohistochemistry disclosed positive stain for protein S-100 and CD1 antigenic determinant. Pediatric oncology evaluation was completely normal. Eighteen months after presentation, the patient remained healthy without recurrence of the lesion.
  
  
  CONCLUSIONS
  Rare cases of congenital histiocytosis can present as a solitary lesion over the palpebral conjunctiva, without skin or systemic involvement.
authors.affiliation: Department of Ophthalmology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
authors.forename: Tova
authors.initials: T
authors.lastname: Monos
authors.forename: Jaime
authors.initials: J
authors.lastname: Levy
authors.forename: Tova
authors.initials: T
authors.lastname: Lifshitz
authors.forename: Ronit
authors.initials: R
authors.lastname: Yagev
authors.forename: Esther
authors.initials: E
authors.lastname: Maor
mesh_terms: D018949:Antigens, CD1 / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D003228:Conjunctiva / Q000378:metabolism / Q000473:pathology; D003229:Conjunctival Diseases / Q000151:congenital* / Q000000981:diagnostic imaging / Q000601:surgery; D015614:Histiocytosis / Q000151:congenital* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007231:Infant, Newborn; D008297:Male; D009418:S100 Proteins / Q000378:metabolism; D014057:Tomography, X-Ray Computed
chemical_list: D018949:Antigens, CD1; D015415:Biomarkers; C419393:CD1a antigen; D009418:S100 Proteins