The role of blood cells and their microparticles in blood coagulation.
The transmembrane glycoprotein TF (tissue factor) plays an essential role in haemostasis as the principal initiator of blood coagulation. In this paper, we describe how the circulating blood cells--monocytes, platelets, neutrophils and their microparticles--co-operate in regulating the expression, availability and activity of monocyte-derived TF.
Eilertsen
K-E
KE
Department of Biochemistry, Institute of Medical Biology, Faculty of Medicine, University of Tromsø, N-9037 Tromsø, Norway.
Østerud
B
B
D000818:Animals; D001777:Blood Coagulation / Q000502:physiology*; D001792:Blood Platelets / Q000378:metabolism*; D006098:Granulocytes / Q000378:metabolism*; D009000:Monocytes / Q000378:metabolism*; D013925:Thromboplastin / Q000378:metabolism
D013925:Thromboplastin