Teaching resources. Structure of G-protein-coupled receptors and G proteins.
This Teaching Resource provides lecture notes and slides for a class covering the structure and function of G protein-coupled receptors and is part of the course "Cell Signaling Systems: A Course for Graduate Students." The lecture begins with a discussion of the crystal structure of rhodopsin and G protein subunits and then proceeds to describe the molecular mechanisms of receptor activation and the subsequent release of G proteins.
Iyengar
Ravi
R
Department of Pharmacology and Biological Chemistry, Mount Sinai School of Medicine, New York, NY 10029, USA. ravi.iyengar@mssm.edu <ravi.iyengar@mssm.edu>
D000818:Animals; D001296:Audiovisual Aids; D001695:Biology / Q000193:education*; D019281:Dimerization; D004500:Education, Graduate; D004789:Enzyme Activation; D019204:GTP-Binding Proteins / Q000502:physiology*; D006160:Guanosine Triphosphate / Q000502:physiology; D006801:Humans; D051379:Mice; D011487:Protein Conformation; D043562:Receptors, G-Protein-Coupled / Q000737:chemistry / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D013329:Structure-Activity Relationship
D043562:Receptors, G-Protein-Coupled; D006160:Guanosine Triphosphate; D019204:GTP-Binding Proteins