Bioactive constituents from Dracocephalum subcapitatum (O. Kuntze) Lipsky.
From an EtOAc extract of Dracocephalum subcapitatum, five flavonoids, calycopterin, xanthomicrol, isokaempferide, luteolin and apigenin, together with five terpenoids, oleanolic acid, ursolic acid, geranial, neral and limonene-10-al, were isolated. Among them, citral and limonene-10-al were the most effective components against epimastigotes of Trypanosoma cruzi, the parasitic agent of Chagas disease.
Saeidnia
Soodabeh
S
Department of Pharmacognosy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, PO Box 48175-861, Sari, Iran. soodabehsaeidnia@hotmail.com
Gohari
Ahmad Reza
AR
Ito
Michiho
M
Kiuchi
Fumiyuki
F
Honda
Gisho
G
D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D035264:Flowers / Q000737:chemistry; D019686:Lamiaceae / Q000737:chemistry* / Q000378:metabolism; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification*
D005419:Flavonoids; D010936:Plant Extracts; D013729:Terpenes