title: Multiple osteochondral arthroscopic grafting (mosaicplasty) for cartilage defects of the knee: prospective study results at 2-year follow-up.
abstract: OBJECTIVE
  To prospectively evaluate the mosaicplasty technique for treatment of femoral condyle cartilage lesions (Outerbridge grade IV) less than 2.5 cm2 in homogeneous group of young active patients.
  
  
  METHODS
  Case series.
  
  
  METHODS
  Thirty-seven patients (10 female, 27 male; mean age, 29.5 years) with full-thickness knee chondral lesions were treated by the arthroscopic mosaicplasty technique. All patients practiced sports. There were 12 ACL reconstructions, 11 medial meniscectomies, and 8 lateral meniscectomies associated; 10 meniscectomies, 9 ACL reconstructions, and 5 cartilage reparative operations had been previously performed. All patients were evaluated at a 2-year follow-up. The International Cartilage Repair Society (ICRS) form, return to sports, computed tomography, or magnetic resonance imaging were used for clinical evaluation. In some cases, second-look arthroscopy was performed.
  
  
  RESULTS
  The ICRS showed 78.3% good and excellent results; 27 patients returned to sports at the same level and 5 at a lower level, but 5 were not able to resume sports. Results in the lateral condyles were significantly better than those in medial condyles, and younger patients had a better clinical outcome than did older patients. Cases with associated surgery had better clinical results; previous surgery did not significantly influence the clinical outcome.
  
  
  CONCLUSIONS
  The results of this technique at medium-term follow-up are encouraging with 78.3% clinically satisfactory results. Better results can be obtained in young patients with associated surgery, with localized grade 4 lesions of the lateral condyles. This arthroscopic 1-step surgery appears to be a valid solution for the treatment of grade III-IV cartilage defects not more than 2.5 cm2.
  
  
  METHODS
  Level IV, Case Series.
authors.affiliation: Istituti Ortopedici Rizzoli, Bologna, Italy.
authors.forename: Maurilio
authors.initials: M
authors.lastname: Marcacci
authors.forename: Elizaveta
authors.initials: E
authors.lastname: Kon
authors.forename: Stefano
authors.initials: S
authors.lastname: Zaffagnini
authors.forename: Francesco
authors.initials: F
authors.lastname: Iacono
authors.forename: Maria Pia
authors.initials: MP
authors.lastname: Neri
authors.forename: Alberto
authors.initials: A
authors.lastname: Vascellari
authors.forename: Andrea
authors.initials: A
authors.lastname: Visani
authors.forename: Alessandro
authors.initials: A
authors.lastname: Russo
mesh_terms: D000328:Adult; D001265:Athletic Injuries / Q000601:surgery*; D016025:Bone Transplantation / Q000379:methods; D002357:Cartilage Diseases / Q000534:rehabilitation / Q000601:surgery*; D002358:Cartilage, Articular / Q000033:anatomy & histology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007718:Knee Injuries / Q000534:rehabilitation / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D018709:Statistics, Nonparametric; D013997:Time Factors; D014182:Transplantation, Autologous