[Kidney tumors in childhood].
Types of renal tumors arising in children are different from those occurring in adults. Nephroblastoma is the most common (85%) with a clinical outcome which has dramatically improved in the last 30 years. Current classifications are aimed at better adaptation of treatment to each individual case, reducing iatrogenic complications without impairing total cure. Amongst entities which have been recently described or are better known we can find juvenile carcinoma associated with Xp11.2 translocation, renal medullary carcinoma, metanephric tumors, etc. Role of molecular cytogenetics is increasing for classification (and treatment) and this should always be kept in mind when dealing a fresh specimen of childhood renal tumor.
Perlman
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Department of Pathology, Children's Memorial Hospital, Annex Bldg, Room A204, 2373 N. Lincold Avenue, Chicago, IL 60614, USA.
Boccon-Gibod
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L
D000328:Adult; D000367:Age Factors; D002648:Child; D006801:Humans; D007680:Kidney Neoplasms / Q000145:classification* / Q000188:drug therapy / Q000473:pathology*; D011379:Prognosis; D009396:Wilms Tumor / Q000145:classification / Q000188:drug therapy / Q000473:pathology*