title: Compliance of Dutch orthopedic departments with national guidelines on thromboprophylaxis. A survey of Dutch orthopedic thromboprohylaxis.
abstract: All 110 Dutch orthopedic departments were sent a survey on perioperative thromboprophylaxis protocols, and 79% responded. After hip and knee replacements, all used pharmacological thromboprophylaxis: a low-molecular weight heparin (LMWH) in 87% of departments, which was most often combined with vitamin K antagonists (VKAs). LMWH was usually started preoperatively (91%). After discharge, VKAs were mostly prescribed (79%) for at least 6 weeks, and often for 3 months. 17% of departments used LMWH for 6 weeks, whereas in only 3% no post-discharge prophylaxis was given. In day-care surgery, including arthroscopies, 58% use LMWH and in short-stay surgery 80% administer LMWH during the hospital stay. Because of lack of conclusive evidence for day-care surgery, the national guidelines cannot support pharmacological prophylaxis in this setting. In general, Dutch orthopedic departments comply poorly with the national guidelines on extended thromboprophylaxis for hip and knee replacement surgery, which recommends postoperative LMWH for 6 weeks. They are divided in the use of pharmacological prophylaxis in day-care surgery.
authors.affiliation: Department of Orthopedic Surgery and Traumatology, Isala Clinics, De Weezenlanden Hospital, Zwolle, The Netherlands.
authors.forename: Harmen B
authors.initials: HB
authors.lastname: Ettema
authors.forename: Marnix R
authors.initials: MR
authors.lastname: Hoppener
authors.forename: Christiaan P
authors.initials: CP
authors.lastname: Henny
authors.forename: Harry R
authors.initials: HR
authors.lastname: Büller
authors.forename: Cees C P M
authors.initials: CC
authors.lastname: Verheyen
mesh_terms: D005343:Fibrinolytic Agents / Q000008:administration & dosage; D019983:Guideline Adherence; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage; D006801:Humans; D009426:Netherlands; D011183:Postoperative Complications / Q000517:prevention & control*; D017410:Practice Guidelines as Topic; D011795:Surveys and Questionnaires; D013927:Thrombosis / Q000517:prevention & control*; D014812:Vitamin K / Q000037:antagonists & inhibitors
chemical_list: D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; D014812:Vitamin K