title: Infection in hip arthroplasty after previous injection of steroid.
abstract: Immunosuppression following intra-articular injections of steroid into the hip may interfere with asepsis in a subsequent total hip arthroplasty (THA). We have undertaken a retrospective, matched, cohort study of infective complications after THA, in 40 patients who had received such an injection and 40 who had not. In the injection group there were five revisions, four of which were for deep infection. There were none in the matched group. The overall rate of revision in our database of 979 primary THAs was 1.02%. Six additional patients who had received injections underwent investigation for infection because of persistent problems in the hip as compared with one in the control group.
authors.affiliation: McMaster University, Hamilton, Ontario K8V 1C3, Canada. mightysamster1@aol.com
authors.forename: S
authors.initials: S
authors.lastname: Kaspar
authors.forename: J
authors.initials: J
authors.lastname: de V de Beer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000009:adverse effects; D019644:Arthroplasty, Replacement, Hip; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007270:Injections, Intra-Articular; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000209:etiology* / Q000276:immunology; D015207:Osteoarthritis, Hip / Q000188:drug therapy* / Q000601:surgery; D016459:Prosthesis-Related Infections / Q000209:etiology* / Q000276:immunology; D012086:Reoperation; D012189:Retrospective Studies; D013256:Steroids / Q000009:adverse effects*; D016019:Survival Analysis
chemical_list: D000893:Anti-Inflammatory Agents; D013256:Steroids