[Moderate cognitive impairment syndrome in cerebral vascular insufficiency].
Frequency of clinical and psychological peculiarities of moderate (mild) cognitive impairment (MCI) in cerebral vascular insufficiency (CVI) was studied in 42 patients, mean age 67.7 +/- 7.7 years. Along with neurological examination, a battery of psychiatric and neuropsychological scales and tests was used. MCI was diagnosed in 28 (66.7%) patients. In 20 patients (47.6%), cognitive hypoactivity was most prominent related to impaired neurodynamics and regulation of voluntary activity which may reflect subcortical and frontal lobes functions. In 8 patients (20.1%), there was a prominent memory impairment characteristic of hippocampus lesion. The authors suggest the presence of concomitant neurodegeneration in patients with amnesic MCI.
Iakhno
N N
NN
Zakharov
V V
VV
Lokshina
A B
AB
D000368:Aged; D002561:Cerebrovascular Disorders / Q000150:complications* / Q000175:diagnosis; D016009:Chi-Square Distribution; D003072:Cognition Disorders / Q000145:classification / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D003863:Depression / Q000175:diagnosis; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology; D006624:Hippocampus / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis* / Q000209:etiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D013577:Syndrome