Isolated congenital histiocytosis in the palpebral conjunctiva in a newborn.
OBJECTIVE
To report a rare case of congenital histiocytosis in a newborn without skin involvement.


METHODS
Interventional case-report.


METHODS
A full-term baby presented with a mass over the palpebral conjunctiva of his left upper lid. Ophthalmic examination was otherwise normal, and the baby was healthy. There were no skin lesions.


RESULTS
The lesion was completely removed surgically. Pathologic examination demonstrated a cellular infiltrate composed of eosinophils and histiocytes. Immunohistochemistry disclosed positive stain for protein S-100 and CD1 antigenic determinant. Pediatric oncology evaluation was completely normal. Eighteen months after presentation, the patient remained healthy without recurrence of the lesion.


CONCLUSIONS
Rare cases of congenital histiocytosis can present as a solitary lesion over the palpebral conjunctiva, without skin or systemic involvement.
Monos
Tova
T
Department of Ophthalmology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Levy
Jaime
J
Lifshitz
Tova
T
Yagev
Ronit
R
Maor
Esther
E
D018949:Antigens, CD1 / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D003228:Conjunctiva / Q000378:metabolism / Q000473:pathology; D003229:Conjunctival Diseases / Q000151:congenital* / Q000000981:diagnostic imaging / Q000601:surgery; D015614:Histiocytosis / Q000151:congenital* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007231:Infant, Newborn; D008297:Male; D009418:S100 Proteins / Q000378:metabolism; D014057:Tomography, X-Ray Computed
D018949:Antigens, CD1; D015415:Biomarkers; C419393:CD1a antigen; D009418:S100 Proteins