Acute unilateral leukemic hypopyon in an adult with relapsing acute lymphoblastic leukemia.
OBJECTIVE
To report acute unilateral hypopyon uveitis as an initial presenting feature of relapsing acute lymphoblastic leukemia (ALL) in an adult patient.


METHODS
Observational case report.


METHODS
Anterior chamber paracentesis was performed in a 56-year-old male presenting with treatment-resistant unilateral hypopyon while in the remission phase of ALL.


RESULTS
Examination of the aqueous humor aspirate revealed presence of malignant cells compatible with the previous bone marrow biopsy and subsequent spinal tap results.


CONCLUSIONS
Atypical hypopyon uveitis can be an indication of relapsing ALL, even in adults. Prompt anterior chamber aspiration is required for the correct diagnosis and subsequent treatment.
Yi
David H
DH
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.
Rashid
Saadia
S
Cibas
Edmund S
ES
Arrigg
Paul G
PG
Dana
M Reza
MR
D000867:Anterior Chamber / Q000473:pathology*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001082:Aqueous Humor / Q000166:cytology; D001854:Bone Marrow Cells / Q000473:pathology; D002555:Cerebrospinal Fluid / Q000166:cytology; D005134:Eye Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D005901:Glaucoma / Q000175:diagnosis; D006801:Humans; D007429:Intraocular Pressure; D017254:Leukemic Infiltration; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D013492:Suppuration / Q000175:diagnosis; D014606:Uveitis, Anterior / Q000175:diagnosis*