title: Anti-inflammatory metabolites from marine sponges.
abstract: Marine sponges are a rich source of biologically active secondary metabolites with novel chemical structures. Eighty four anti-inflammatory compounds have been isolated from marine sponges. This is the first comprehensive review presenting the structures and anti-inflammatory activities of marine sponge metabolites. (100 references).
authors.affiliation: Chemistry Department, Rhodes University, Grahamstown 6140, South Africa. r.keyzers@ru.ac.za
authors.forename: Robert A
authors.initials: RA
authors.lastname: Keyzers
authors.forename: Michael T
authors.initials: MT
authors.lastname: Davies-Coleman
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D002351:Carrageenan / Q000737:chemistry; D004487:Edema / Q000139:chemically induced / Q000517:prevention & control; D006801:Humans; D008968:Molecular Conformation; D010741:Phospholipases A / Q000037:antagonists & inhibitors; D011161:Porifera / Q000737:chemistry*; D013481:Superoxides / Q000037:antagonists & inhibitors
chemical_list: D000893:Anti-Inflammatory Agents; D013481:Superoxides; D002351:Carrageenan; D010741:Phospholipases A