title: Monitoring measles elimination in Victoria.
abstract: OBJECTIVE
  To weigh the evidence from outbreak data that Victoria has achieved, and is maintaining, elimination of measles. To identify age groups that measles vaccination has not protected adequately.
  
  
  METHODS
  Data on observed measles outbreaks in Victoria since the start of 1998 are used to estimate the reproduction number of cases, and the probability that it is maintained below unity, its threshold value for elimination. The relative susceptibility to measles is estimated as a function of age, with confidence intervals.
  
  
  RESULTS
  Seventeen measles introductions led to secondary cases, while 22 were single-case introductions. From these, the probability that the reproduction number for cases exceeds unity is estimated to be 0.044, or less, depending on assumptions made. There is no evidence that the reproduction number increased over time. Those aged between 19 and 32 years were most susceptible, followed by those in the first and second year of life.
  
  
  CONCLUSIONS
  The data provide strong evidence that Victoria has maintained elimination of measles over the period 1998 to mid-2003. There is scope to improve the immunisation coverage. It is not clear how much outbreak intervention is contributing to the success in achieving apparent elimination.
  
  
  CONCLUSIONS
  To prevent importations from causing a major epidemic of measles, Victoria must maintain its immunisation coverage and outbreak control at current levels, or better. It is important to monitor the control of measles even when elimination is achieved.
authors.affiliation: National Centre for Epidemiology and Population Health, Australian National University, Australian Capital Territory. niels.becker@anu.edu.au
authors.forename: Niels G
authors.initials: NG
authors.lastname: Becker
authors.forename: Zhengfeng
authors.initials: Z
authors.lastname: Li
authors.forename: Edmond
authors.initials: E
authors.lastname: Hsu
authors.forename: Ross M
authors.initials: RM
authors.lastname: Andrews
authors.forename: Stephen B
authors.initials: SB
authors.lastname: Lambert
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D003140:Communicable Disease Control / Q000379:methods*; D004196:Disease Outbreaks / Q000517:prevention & control*; D005260:Female; D006801:Humans; D017589:Immunization Programs; D007115:Immunization Schedule; D008297:Male; D008457:Measles / Q000453:epidemiology / Q000517:prevention & control*; D008458:Measles Vaccine / Q000008:administration & dosage*; D011159:Population Surveillance; D018570:Risk Assessment; D012737:Sex Factors; D014611:Vaccination / Q000592:standards / Q000639:trends; D014739:Victoria / Q000453:epidemiology
chemical_list: D008458:Measles Vaccine