Life-threatening airway obstruction caused by mediastinal germinoma in a 9-year-old girl.
The authors report a case of a 9-year-old girl with a mediastinal germinoma that required emergent surgical extirpation because of tracheal compression and asphyxia. The tumor was successfully debulked under general anesthesia with the capability of extracorporeal circulation immediately available. Postoperatively, the tumor responded to adjuvant chemotherapy and irradiation and the patient survived without evidence of recurrence.
Morikawa
Nobuyuki
N
Department of Surgery, National Center for Child Health and Development, Tokyo 157-8535, Japan. morikawa-n@ncchd.go.jp
Honna
Toshiro
T
Kuroda
Tatsuo
T
Tanaka
Kiyoshi
K
Kitano
Yoshihiro
Y
Nakano
Miwako
M
Matsuda
Hiromitsu
H
Tanaka
Keiichiro
K
Kawashima
Noriko
N
Miyauchi
Jun
J
D000402:Airway Obstruction / Q000209:etiology*; D000768:Anesthesia, General; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D001237:Asphyxia / Q000209:etiology; D001249:Asthma / Q000175:diagnosis; D001761:Bleomycin / Q000008:administration & dosage; D016190:Carboplatin / Q000008:administration & dosage; D017024:Chemotherapy, Adjuvant; D002648:Child; D003131:Combined Modality Therapy; D000075202:Contraindications; D003951:Diagnostic Errors; D004417:Dyspnea / Q000209:etiology; D004630:Emergencies; D004829:Epilepsy, Generalized / Q000209:etiology; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D018237:Germinoma / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D000860:Hypoxia / Q000209:etiology; D008479:Mediastinal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D012074:Remission Induction; D014057:Tomography, X-Ray Computed; D014135:Tracheal Stenosis / Q000209:etiology*
D001761:Bleomycin; D005047:Etoposide; D016190:Carboplatin