title: Posterior resection for childhood epilepsy.
abstract: We reviewed our experience with posterior resection for intractable childhood epilepsy. Fifteen patients, seven males and eight females, were studied. Age of surgery was 18 months to 16 years. Nine patients had a parietal resection and six patients had an occipital resection. Surgical outcome was variable. Nine patients had an excellent outcome (Engel Class I or II), two patients had a poor outcome (Engel Class III), and four patients had a very poor outcome (Engel Class IV). Pathology at surgery included focal cortical dysplasias (4), brain tumors (4), tubers of tuberous sclerosis (2), cerebrovascular accidents (2), porencephalic cysts (1), and normal pathology (2). Complications included visual field loss in the occipital lobe patients (4/6). Posterior resection can be successful for children with intractable epilepsy originating in the parietal and occipital lobes. Invasive monitoring is necessary in some patients to establish the extent of the epileptic zone before surgery. A good surgical outcome is dependent on the presence of a circumscribed lesion on MRI and ability to surgically remove all the pathology. Visual abnormalities are an expected complication of surgery in the occipital lobe, but may improve over time.
authors.affiliation: Comprehensive Epilepsy Program, University of Alberta Hospital, Edmonton, Alberta, Canada.
authors.forename: D Barry
authors.initials: DB
authors.lastname: Sinclair
authors.forename: Matt
authors.initials: M
authors.lastname: Wheatley
authors.forename: Thomas
authors.initials: T
authors.lastname: Snyder
authors.forename: Donald
authors.initials: D
authors.lastname: Gross
authors.forename: Nizam
authors.initials: N
authors.lastname: Ahmed
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009778:Occipital Lobe / Q000601:surgery*; D010296:Parietal Lobe / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome