Modelling of anisotropic growth in biological tissues. A new approach and computational aspects.
In this contribution, we develop a theoretical and computational framework for anisotropic growth phenomena. As a key idea of the proposed phenomenological approach, a fibre or rather structural tensor is introduced, which allows the description of transversely isotropic material behaviour. Based on this additional argument, anisotropic growth is modelled via appropriate evolution equations for the fibre while volumetric remodelling is realised by an evolution of the referential density. Both the strength of the fibre as well as the density follow Wolff-type laws. We however elaborate on two different approaches for the evolution of the fibre direction, namely an alignment with respect to strain or with respect to stress. One of the main benefits of the developed framework is therefore the opportunity to address the evolutions of the fibre strength and the fibre direction separately. It is then straightforward to set up appropriate integration algorithms such that the developed framework fits nicely into common, finite element schemes. Finally, several numerical examples underline the applicability of the proposed formulation.
Menzel
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Department of Mechanical and Process Engineering, University of Kaiserslautern, P.O. Box 3049, 67653 Kaiserslautern, Germany. amenzel@rhrk.uni-kl.de
D000818:Animals; D016880:Anisotropy; D016764:Cell Polarity; D049109:Cell Proliferation; D003198:Computer Simulation; D003238:Connective Tissue / Q000254:growth & development*; D006801:Humans; D040542:Mechanotransduction, Cellular / Q000502:physiology*; D008954:Models, Biological