title: Steroid-responsive inclusion body myositis associated with endometrial cancer.
abstract: Inclusion body myositis (IBM) is an uncommon chronic inflammatory myopathy. Although the association between other myopathies and cancer has been well established, the relationship between IBM and neoplasia is not completely understood. Unlike polymyositis (PM) or dermatomyositis (DM), IBM rarely responds to immunosuppressive treatment and the response is seldom long-lasting. We describe a case of IBM associated with endometrial carcinoma that also demonstrated a unique response to steroids alone which persisted despite cancer relapse. The factors that are associated with a response of IBM to steroids are discussed. An atypical, steroid-responsive form of the disease is delineated.
authors.affiliation: Comprehensive Cancer Center, Our Lady of Mercy Medical Center, Bronx, New York 10466, USA. mddoru@hotmail.com
authors.forename: D T
authors.initials: DT
authors.lastname: Alexandrescu
authors.forename: N S
authors.initials: NS
authors.lastname: Bhagwati
authors.forename: B
authors.initials: B
authors.lastname: Fomberstein
authors.forename: D E
authors.initials: DE
authors.lastname: Wolfe
authors.forename: A
authors.initials: A
authors.lastname: Feliz
authors.forename: P H
authors.initials: PH
authors.lastname: Wiernik
mesh_terms: D000230:Adenocarcinoma / Q000150:complications*; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D003402:Creatine Kinase / Q000097:blood; D016889:Endometrial Neoplasms / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D018979:Myositis, Inclusion Body / Q000097:blood / Q000150:complications* / Q000188:drug therapy
chemical_list: D000305:Adrenal Cortex Hormones; D003402:Creatine Kinase