title: [Studies on constituents from the fermentation of Alternalia sp].
abstract: OBJECTIVE
  To study the metabolites of marine fungus Alternalia sp.
  
  
  METHODS
  Compounds were separated by column chromatography and their structures were elucidated by means of chemical and spectral analysis.
  
  
  RESULTS
  Six compounds were isolated from the ethyl acetate and n-butanol extracts of the fermentation of marine fungus Alternalia sp. Their structures were elucidated as p-benzyloxy-phenol ( I ), p-hydroxy phenyl ethylamine( II ), 3-hydroxymethyl-8-hydroxyl-pyrrolopiperazine-2, 5-dione ( III ), 3-isobutyl-6-secbutyl-piperazine-2, 5-dione (IV), 5alpha, 8alpha-epidioxy-ergosta-6, 22-diene-3beta-ol (V), 3beta-hydroxxy-cholesta-5-ene (VI).
  
  
  CONCLUSIONS
  Compounds I , II, III, IV have the activity of inducing morphological deformation of mycelia germinated from conidia of Pyricularia oryzae. Compounds I , II , III were isolated from the genus Alternalia for the first time.
authors.affiliation: School of Traditional Chinese Medicines, Shenyang Pharmaceutical University, Shenyang 110016, China.
authors.forename: Hai-long
authors.initials: HL
authors.lastname: Zhang
authors.forename: Li
authors.initials: L
authors.lastname: Tian
authors.forename: Hong wei
authors.initials: Hw
authors.lastname: Fu
authors.forename: Yue-hu
authors.initials: YH
authors.lastname: Pei
authors.forename: Hui-ming
authors.initials: HM
authors.lastname: Hua
mesh_terms: D000935:Antifungal Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001203:Ascomycota / Q000187:drug effects; D005285:Fermentation; D005658:Fungi / Q000737:chemistry*; D015394:Molecular Structure; D010627:Phenethylamines / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D010627:Phenethylamines; D010636:Phenols