Comparison of diced cartilage graft wrapped in surgicell and diced cartilage graft wrapped in fascia: an experimental study.
OBJECTIVE
This study was conducted to compare diced cartilage grafts wrapped in fascia and diced cartilage grafts wrapped in surgicell with respect to their resorption.


METHODS
Experimental study.


METHODS
Eight male Wistar Albino rats were used. After general anesthesia, two different subcutaneous pockets (upper and lower pocket) were prepared in the rat's abdomen. Surgicell-wrapped homograft that was taken from the ear was placed into the upper subcutaneous pocket. Fascia-wrapped homograft which was taken from the ear was placed into the lower subcutaneous pocket. All the rats were killed at the end of 2 months, and the samples were collected to be examined histopathologically. Cartilage mass, foreign body reaction, fibrosis, chronic inflammation, and vascularization were researched.


RESULTS
Diced cartilage wrapped surgicell stained negative for glial fibrillary acidic protein (GFAP). Diced cartilage wrapped in fascia stained positive for GFAP. There was a significant difference between two groups with respect to fibrosis, chronic inflammation, and cartilage mass. There was no significant difference between the two groups regarding vascularization.


CONCLUSIONS
This study suggests that diced cartilage graft wrapped in surgicell was absorbed, whereas diced cartilage graft wrapped in fascia was not.
Coskun
Berna Uslu
BU
Department of Otorhinolaryngology, Sisli Etfal Training and Research Hospital, Istanbul, Turkey. bernauslu@tnn.net
Seven
Huseyin
H
Yigit
Ozgur
O
Alkan
Seyhan
S
Savk
Hayati
H
Basak
Tulay
T
Dadas
Burhan
B
D000042:Absorption; D000818:Animals; D001672:Biocompatible Materials / Q000627:therapeutic use*; D002356:Cartilage / Q000473:pathology / Q000637:transplantation*; D002483:Cellulose, Oxidized / Q000627:therapeutic use*; D004396:Coloring Agents; D062109:Dermatologic Surgical Procedures; D005205:Fascia / Q000473:pathology / Q000637:transplantation*; D005355:Fibrosis; D005549:Foreign-Body Reaction / Q000473:pathology; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D007249:Inflammation; D008297:Male; D018919:Neovascularization, Physiologic / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D012867:Skin / Q000473:pathology; D013997:Time Factors
D001672:Biocompatible Materials; D002483:Cellulose, Oxidized; D004396:Coloring Agents; D005904:Glial Fibrillary Acidic Protein; C013695:Surgicel