Latent autoimmune diabetes of adulthood. Unique features that distinguish it from types 1 and 2.
A number of patients with poor glycemic control receive the diagnosis of type 2 diabetes despite the fact that they do not exhibit some of the traditional characteristics of the disease, such as obesity. A more accurate diagnosis for many of these patients is latent autoimmune diabetes of adulthood (LADA). In this article, Dr Nabhan and coauthors describe features that LADA has in common with type 1 and type 2 diabetes, as well as those that distinguish LADA from these more widely recognized forms of diabetes. The authors also describe the pathogenesis of the disease, potential complications, and treatment options.
Nabhan
Fadi
F
Division of Endocrinology and Metabolism, Loyola University Medical Center, Maywood, Illinois 60153, USA. fnabhan@lumc.edu
Emanuele
Mary Ann
MA
Emanuele
Nicholas
N
D001323:Autoantibodies / Q000032:analysis; D048909:Diabetes Complications; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology* / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology* / Q000503:physiopathology; D005968:Glutamate Decarboxylase / Q000276:immunology; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007333:Insulin Resistance; D007515:Islets of Langerhans / Q000276:immunology
D001323:Autoantibodies; D007004:Hypoglycemic Agents; D005968:Glutamate Decarboxylase