title: Comparison of fibrin glue and sutures for attaching conjunctival autografts after pterygium excision.
abstract: OBJECTIVE
  To compare the efficacy and safety of fibrin glue and suturing for attaching conjunctival autografts among patients undergoing pterygium excision.
  
  
  METHODS
  Prospective, randomized, interventional case series.
  
  
  METHODS
  Twenty-two patients undergoing excision of primary pterygium.
  
  
  METHODS
  A superior conjunctival autograft was harvested and transferred onto bare sclera after pterygium excision. Fibrin glue (Beriplast P) was used to attach the autograft in 11 eyes and nylon 10-0 suture was used to attach the autograft in 11 eyes. The patients were followed up for 2 months.
  
  
  METHODS
  Graft success, recurrence rate, operating time, patient comfort.
  
  
  RESULTS
  All conjunctival autografts in both groups were successfully attached and were intact after 2 months. The average operating time for the fibrin glue group was significantly shorter (P<0.001). Postoperative symptoms were fewer for the fibrin glue group than the suture group. One patient (9%) from the fibrin group experienced subconjunctival hemorrhage, and 1 patient (9%) from the suture group experienced partial graft dehiscence.
  
  
  CONCLUSIONS
  Fibrin glue is a safe and effective method for attaching conjunctival autografts. The use of fibrin glue results in shorter operating times and less postoperative discomfort.
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of the Philippines, Philippine General Hospital, Manila, Philippines. harveyuy@yahoo.com
authors.forename: Harvey S
authors.initials: HS
authors.lastname: Uy
authors.forename: Johann Michael G
authors.initials: JM
authors.lastname: Reyes
authors.forename: John D G
authors.initials: JD
authors.lastname: Flores
authors.forename: Ruben
authors.initials: R
authors.lastname: Lim-Bon-Siong
mesh_terms: D000328:Adult; D000368:Aged; D003228:Conjunctiva / Q000637:transplantation*; D005260:Female; D015718:Fibrin Tissue Adhesive; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011183:Postoperative Complications / Q000517:prevention & control; D011446:Prospective Studies; D011625:Pterygium / Q000601:surgery*; D012449:Safety; D013536:Suture Techniques; D014014:Tissue Adhesives; D014182:Transplantation, Autologous; D016896:Treatment Outcome
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives