Effect of antibiotics on growth and laccase production from Cyathus bulleri and Pycnoporus cinnabarinus.
The effect of nine different antibiotics (chloramphenicol, ampicillin trihydrate, kanamycin A monosulfate, neomycin sulfate, erythromycin, thiostrepton, tetracycline, apramycin sulfate and streptomycin sulfate) on growth and laccase production from Cyathus bulleri and Pycnoporus cinnabarinus has been investigated. All the antibiotics tested at a concentration of 200 mg/l affected the fungal growth, release of protein and laccase production to different extent. Inhibition in fungal growth was found to be positively correlated with increase in laccase production. Interestingly, apramycin sulfate inhibited biomass production (14.9-26.2%), nevertheless, it stimulated maximum laccase production (18.2 U/ml) in both the fungi. Increasing concentrations of apramycin sulfate enhanced laccase production from P. cinnabarinus but not from C. bulleri.
Dhawan
Shikha
S
Department of Microbiology, University of Delhi South Campus, Benito Juarez Road, New Delhi 110021, India.
Lal
Rup
R
Hanspal
Manjit
M
Kuhad
Ramesh Chander
RC
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001487:Basidiomycota / Q000187:drug effects* / Q000201:enzymology* / Q000254:growth & development; D042845:Laccase / Q000096:biosynthesis*; D013997:Time Factors
D000900:Anti-Bacterial Agents; D042845:Laccase