title: A case of systemic osteomyelitides due to Mycobacterium avium.
abstract: A case of multiple osteomyelitides due to Mycobacterium avium (M. avium) infection with osteosclerotic bone lesions is reported. A 67-year-old male had been suffering from persistent fever and back pain since October 1999, and 20.0-2.5 mg prednisolone per day was prescribed for continuous inflammatory symptoms in January 2000. Six months later, computed tomography revealed osteosclerotic lesions in the left femur and thoracic vertebrae, but no skin lesion associated with mastocytosis or internal malignancy was identified. In September of 2002, a dome-shaped, soft subcutaneous tumor developed on the upper sternum. Histopathological findings revealed subcutaneous adipose tissue with several foci of tiny abscesses. Two weeks later, creamy pus was discharged through a draining sinus at the center of the wound. M. avium was demonstrated in the pus by Zeel-Nielsen staining and microplate hybridization.
authors.affiliation: Department of Dermatology, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo 060-8543, Japan.
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Yamashita
authors.forename: Takao
authors.initials: T
authors.lastname: Endo
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Hamamoto
authors.forename: Hidenari
authors.initials: H
authors.lastname: Akiba
authors.forename: Ichiro
authors.initials: I
authors.lastname: Ono
authors.forename: Kowichi
authors.initials: K
authors.lastname: Jimbow
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005269:Femur; D006801:Humans; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D009162:Mycobacterium avium / Q000302:isolation & purification*; D010019:Osteomyelitis / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D017192:Skin Diseases, Bacterial / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D013904:Thoracic Vertebrae; D014057:Tomography, X-Ray Computed