Use of hormonal replacement therapy after treatment of breast cancer. Number 142, May 2004.
OBJECTIVE
To review the use of hormonal replacement therapy (HRT) after treatment of breast cancer.


METHODS
The effect and role of estrogens on breast cancer.


RESULTS
Improved health and quality of life for women with breast cancer.


METHODS
References were collected through MEDLINE searches up to 2002.


METHODS
The level of evidence and quality of recommendations have been determined using the criteria described by the Canadian Task Force on the Periodic Health Examination.


RESULTS
Utilization of the information to make proper risk-benefit assessment of HRT use in women with breast cancer.


CONCLUSIONS
1. HRT after treatment of breast cancer has not been demonstrated to have an adverse impact on recurrence and mortality. (II-2B). 2. HRT is an option in postmenopausal women with previously treated breast cancer. (II-2B). 3. Prospective, randomized clinical trial results are needed. (III-A).


RESULTS
Recommendations were viewed and revised by the Breast Diseases Committee of the Society of Obstetricians and Gynaecologists of Canada (SOGC) and approved by the Executive and Council of the SOGC.


BACKGROUND
The Society of Obstetricians and Gynaecologists of Canada.
D001943:Breast Neoplasms / Q000453:epidemiology / Q000401:mortality; D015914:Estrogen Replacement Therapy / Q000009:adverse effects; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D016019:Survival Analysis