title: Scratch n' screen for inhibitors of cell migration.
abstract: Yarrow et al. have identified a small molecule inhibitor of cell migration, 3-(4-pyridyl)indole ("Rockout"), that targets Rho-kinase via a novel screening method using a scratch wound healing assay adapted to a high-throughput format and automated microscopy.
authors.affiliation: Molecular and Cell Biology Department, University of California, Berkeley 94720, USA.
authors.forename: Jon
authors.initials: J
authors.lastname: Soderholm
authors.forename: Rebecca
authors.initials: R
authors.lastname: Heald
mesh_terms: D000818:Animals; D002464:Cell Migration Inhibition; D002465:Cell Movement / Q000187:drug effects*; D006801:Humans; D007211:Indoles / Q000494:pharmacology*; D014945:Wound Healing / Q000187:drug effects
chemical_list: D007211:Indoles