title: Late isolated brain metastasis following enucleation for choroidal melanoma.
abstract: Brain metastases from choroidal melanoma are rare and usually have a grave prognosis. A case of successfully treated late isolated brain metastasis from choroidal melanoma is described. A 35-year-old man presented with epileptic seizures of recent origin, 9 years following enucleation for choroidal melanoma. Imaging studies revealed a lesion of the right frontal lobe that was surgically removed. Results of pathologic examination were compatible with metastatic choroidal melanoma. The patient is asymptomatic 5 years postoperatively. Late isolated brain metastases from uveal melanoma may be treatable by local resection. Close, lifelong follow-up is required to diagnose and aggressively treat metastatic disease.
authors.affiliation: Department of Ophthalmology, 492 General Army Hospital, Alexandroupolis, Greece.
authors.forename: Athanassios K
authors.initials: AK
authors.lastname: Achtaropoulos
authors.forename: Aristotelis P
authors.initials: AP
authors.lastname: Mitsos
authors.forename: Efstathios T
authors.initials: ET
authors.lastname: Detorakis
authors.forename: Nikolaos V
authors.initials: NV
authors.lastname: Georgakoulias
authors.forename: Eleni E
authors.initials: EE
authors.lastname: Drakonaki
authors.forename: Vassilios P
authors.initials: VP
authors.lastname: Kozobolis
mesh_terms: D000328:Adult; D015901:Angiography, Digital Subtraction; D001932:Brain Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D002830:Choroid Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D015353:Eye Enucleation; D005500:Follow-Up Studies; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D012086:Reoperation; D013997:Time Factors; D014057:Tomography, X-Ray Computed