Evaluation of Binax NOW RSV as an acute point-of-care screening test in a paediatric accident and emergency unit.
Point-of-care tests (POCTs) for respiratory syncytial virus infections are a useful adjunct to reduce the risk of healthcare-associated infections in paediatric wards. A new test based on immunochromatography, Binax NOW RSV, was introduced in the winter of 2002-03. It has user friendly features making it particularly suitable for non-laboratory personnel in a paediatric accident and emergency unit. A prospective study comparing the POCT with laboratory-based direct immunofluorescence (DIF) showed sensitivity of 87% specificity of 94%, positive predictive value of 89% and negative predictive value 92%. The simplicity of Binax NOW RSV should not detract from training staff and maintaining consistent vigilance on quality control.
Mackie
P L
PL
Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN. peter.mackie@arh.grampian.scot.nhs.uk
McCormick
E M
EM
Williams
C
C
D003428:Cross Infection / Q000517:prevention & control*; D004636:Emergency Service, Hospital; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007223:Infant; D008297:Male; D008403:Mass Screening / Q000379:methods*; D019095:Point-of-Care Systems; D011446:Prospective Studies; D018357:Respiratory Syncytial Virus Infections / Q000517:prevention & control*; D018113:Respiratory Syncytial Virus, Human / Q000302:isolation & purification*; D012680:Sensitivity and Specificity