Fright is a provoking factor in vanishing white matter disease.
Leukoencephalopathy with vanishing white matter is an inherited disorder with a chronic progressive disease course and additional episodes of rapid neurological deterioration. These episodes typically are provoked by febrile infections or minor head trauma. We report on two patients who experienced an episode of rapid neurological deterioration after a fright.
Vermeulen
Gerre
G
Department of Pediatrics/Child Neurology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.
Seidl
Rainer
R
Mercimek-Mahmutoglu
Saadet
S
Rotteveel
Jan J
JJ
Scheper
Gert C
GC
van der Knaap
Marjo S
MS
D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D002675:Child, Preschool; D005239:Fear / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011859:Radiography