title: [Effects of triamcinolone acetonide on leukocyte distribution in blood system, mononuclear liver infiltration, and immune response under conditions of stress-induced hypoxia in rats].
abstract: The effect of triamcinolone acetonide (2 mg/kg) on the distribution of morphologically mature leukocytes in the blood system, the mononuclear liver infiltration, and the immune response was studied in rats under conditions of stress-induced hypoxia. Administered under these conditions, the drug produces a less pronounced effect on the content of circulating lymphocytes, the lymphoid cell number in the bone marrow, and the number of hepatocytes and monocytes/macrophages in the liver. However, the post-stressor immunodepressant effect of triamcinolone acetonide was increased and accompanied by the development of hepatic damage.
authors.forename: I A
authors.initials: IA
authors.lastname: Volchegorskiĭ
authors.forename: V E
authors.initials: VE
authors.lastname: Tseĭlikman
authors.forename: O B
authors.initials: OB
authors.lastname: Tseĭlikman
authors.forename: N V
authors.initials: NV
authors.lastname: Bubnov
authors.forename: A I
authors.initials: AI
authors.lastname: Sinitskiĭ
mesh_terms: D000818:Animals; D002465:Cell Movement / Q000187:drug effects* / Q000276:immunology; D005260:Female; D000860:Hypoxia / Q000276:immunology* / Q000473:pathology; D007958:Leukocyte Count; D008099:Liver / Q000276:immunology* / Q000473:pathology; D008214:Lymphocytes / Q000276:immunology / Q000473:pathology; D008264:Macrophages / Q000276:immunology / Q000473:pathology; D008297:Male; D051381:Rats; D013312:Stress, Physiological / Q000276:immunology* / Q000473:pathology; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*
chemical_list: D014222:Triamcinolone Acetonide