title: Infections in the survivors of out-of-hospital cardiac arrest in the first 7 days.
abstract: OBJECTIVE
  To evaluate the incidence, risk factors, foci, isolated organisms, and outcomes of infections in the survivors of out-of-hospital cardiac arrest (OHCA) within the first 7 days after resuscitation.
  
  
  METHODS
  Retrospective cohort study in the intensive care unit of a university hospital.
  
  
  METHODS
  We enrolled 117 survivors of adult nontraumatic OHCA victims who survived more than 24 h between January 1999 and May 2004. We collected patients' demographics, the causes and initial electrocardiographic rhythm of cardiac arrest, and the process of cardiopulmonary resuscitation. The incidence, clinical presentations and outcomes of infections occurring in the first 7 days after resuscitation were evaluated. Variables were compared between the infected and noninfected patients.
  
  
  RESULTS
  Among our OHCA survivors asystole was the most common initial rhythm (66%). Eighty-three patients (71%) were found to have infection. Pneumonia was the most common infection (61%) followed by bacteremia (13%). Although the Gram-negative bacteria were responsible for most infections, the most commonly isolated organism was Staphylococcus aureus. The infection group had more patients with dementia and noncardiac causes of OHCA. The survival curves did not differ significantly between infection and non-infection groups.
  
  
  CONCLUSIONS
  Infections were common in OHCA survivors during the first 7 days. The most common responsible organisms were Gram-negative bacteria, and the most commonly isolated organism was S. aureus. Infections in the early stage after return of spontaneous circulation did not change the hospital mortality and hospitalization duration.
authors.affiliation: Department of Emergency Medicine, National Taiwan University Hospital and College of Medicine, No.7 Chung-Shan S. Road, 100 Taipei, Taiwan.
authors.forename: Min-Shan
authors.initials: MS
authors.lastname: Tsai
authors.forename: Wen-Chu
authors.initials: WC
authors.lastname: Chiang
authors.forename: Chien-Chang
authors.initials: CC
authors.lastname: Lee
authors.forename: Cheng-Chun
authors.initials: CC
authors.lastname: Hsieh
authors.forename: Patrick Chow-In
authors.initials: PC
authors.lastname: Ko
authors.forename: Chiung-Yuan
authors.initials: CY
authors.lastname: Hsu
authors.forename: Chan-Ping
authors.initials: CP
authors.lastname: Su
authors.forename: Shey-Ying
authors.initials: SY
authors.lastname: Chen
authors.forename: Wei-Tein
authors.initials: WT
authors.lastname: Chang
authors.forename: Ang
authors.initials: A
authors.lastname: Yuan
authors.forename: Matthew Huei-Ming
authors.initials: MH
authors.lastname: Ma
authors.forename: Shyr-Chyr
authors.initials: SC
authors.lastname: Chen
authors.forename: Wen-Jone
authors.initials: WJ
authors.lastname: Chen
mesh_terms: D000368:Aged; D016470:Bacteremia / Q000453:epidemiology / Q000382:microbiology; D016887:Cardiopulmonary Resuscitation; D015897:Comorbidity; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000453:epidemiology / Q000382:microbiology; D006323:Heart Arrest / Q000150:complications* / Q000628:therapy; D006801:Humans; D015994:Incidence; D007239:Infections / Q000453:epidemiology*; D007362:Intensive Care Units; D008297:Male; D011014:Pneumonia / Q000453:epidemiology / Q000382:microbiology; D012189:Retrospective Studies; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000453:epidemiology; D013624:Taiwan / Q000453:epidemiology