[Toxins of Vibrio cholerae].
Surveyed in the paper are published data on properties, biological activity, genetic determinants and action mechanisms of recently known toxins produced by different strains of Vibrio cholerae irrespectively of their capacity for the synthesis of choleric toxin--the main virulence factor. Their possible importance both for the general clinical pattern of cholera provoked by cholerogenic agents and as independent virulence factors causing diarrhea without cholera is elucidated. The sets and levels of expression of additional toxins can differ for different pathogenic clones and they can correspondingly condition degrees of their epidemic and etiological safety.
Monakhova
E V
EV
Pisanov
R V
RV
D000818:Animals; D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism*; D001427:Bacterial Toxins / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D002772:Cholera Toxin / Q000276:immunology / Q000378:metabolism; D003967:Diarrhea / Q000276:immunology / Q000382:microbiology*; D019143:Evolution, Molecular; D005798:Genes, Bacterial; D006801:Humans; D008970:Molecular Weight; D014734:Vibrio cholerae / Q000276:immunology / Q000378:metabolism*; D037521:Virulence Factors / Q000276:immunology / Q000378:metabolism
D001426:Bacterial Proteins; D001427:Bacterial Toxins; D037521:Virulence Factors; D002772:Cholera Toxin