Cytotoxic xanthones from Cudrania tricuspidata.
The new isoprenylated tetrahydroxyxanthone, 2,3,6,8-tetrahydroxy-1-(3-methylbut-2-enyl)-5-(2-methylbut-3-en-2-yl)-9H-xanthen-9-one (1), was isolated from the root bark of Cudrania tricuspidata together with macluraxanthone B (2) and cudraxanthone L (3), which were fully characterized by NMR spectroscopic and X-ray crystallographic analyses.
Lee
Byong Won
BW
Department of Agricultural Chemistry, Division of Applied Life Science (BK21 program), The Research Institute of Natural Science, Gyeongsang National University, RAIRC, Jinju 660-701, Korea.
Gal
Sang Wan
SW
Park
Ki-Min
KM
Park
Ki Hun
KH
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018360:Crystallography, X-Ray; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D007723:Korea; D008968:Molecular Conformation; D015394:Molecular Structure; D029586:Moraceae / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D024301:Plant Bark / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D014407:Tumor Cells, Cultured; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
C499913:2,3,6,8-tetrahydroxy-1-(3-methylbut-2-enyl)-5-(2-methylbut-3-en-2-yl)-9H-xanthen-9-one; D000972:Antineoplastic Agents, Phytogenic; D044004:Xanthones; C499914:cudraxanthone L; C419728:macluraxanthone B