IgE: a question of protective immunity in Trichinella spiralis infection.
The best-known function of immunoglobulin E (IgE) is the initiation of allergic reaction. However, it does not make sense that IgE exists only for allergy, which is harmful for the body and does not have a beneficial role. In this article, we focus on IgE in Trichinella spiralis infection in rodents and humans, and discuss the possible roles of IgE in protection and pathogenesis.
Watanabe
Naohiro
N
Department of Tropical Medicine, Jikei University School of Medicine, 3-25-8 Nishishinbashi, Minatoku, Tokyo 105-8461, Japan. naohiro@jikei.ac.jp
Bruschi
Fabrizio
F
Korenaga
Masataka
M
D000818:Animals; D006790:Host-Parasite Interactions; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D051379:Mice; D051381:Rats; D012376:Rodent Diseases / Q000276:immunology / Q000469:parasitology*; D017160:Trichinella spiralis / Q000276:immunology*; D014235:Trichinellosis / Q000276:immunology* / Q000517:prevention & control
D007073:Immunoglobulin E