title: [Study of genetic polymorphism of 6 short tandem repeat loci in Nongqu Mongolian of inner Mongolia Autonomous Region in China].
abstract: OBJECTIVE
  To get the genotype and allele frequency distribution of 6 short tandem repeat (STR) loci VWA, FGA, PENTAE, D6S1043, D2S1772, D7S3048 in NongQu Mongolia of China.
  
  
  METHODS
  Two hundred and ninety-three unrelated individuals from Nongqu Mongolian were investigated. Polymerase chain reaction and polyacrylamide gel electrophoresis were used.
  
  
  RESULTS
  Eighty alleles and 335 genotypes were detected, with frequencies ranging from 0.0017 to 0.2828. All the 6 loci met Hardy-Weinberg equilibrium. The statistical analysis of 6 STR loci showed the heterozygosity (H) >/= 0.7945, the discrimination power (DP) >/= 0.9160, the probability of paternity exclusion (PPE) >/= 0.5919, and the polymorphic information content (PIC) >/= 0.7617.
  
  
  CONCLUSIONS
  These results could serve as valuable data to enrich the Chinese genetic database and play an important role in Chinese population genetic forensic medical application.
authors.affiliation: Research Center of Molecular Biology, Inner Mongolia Medical College, Huhehaote, Inner Mongolia Autonomous Region, 010059 P. R. China.
authors.forename: Shuping
authors.initials: S
authors.lastname: Liu
authors.forename: Lifu
authors.initials: L
authors.lastname: Bi
authors.forename: Xiulan
authors.initials: X
authors.lastname: Su
mesh_terms: D000483:Alleles; D002681:China; D004591:Electrophoresis, Polyacrylamide Gel; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D015810:Linkage Disequilibrium; D018895:Microsatellite Repeats / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics*