title: [Integrated evaluation of chewing gums and candies influence in oral cavity].
abstract: In a blind study on 210 medical students during 3 months the influence of 5 types of chewing gums with sugar substitutes (Orbit, Dirol, Stimorol) and 1 type of candy with sucrose upon saliva properties, saliva flow and oral microflora activity were examined. Flow rate of saliva, its pH (mixed saliva), influence upon test sugar and carbamide pH curves, concentrations of carbamide, Ca and phosphate in saliva were determined. It is shown than frequent and prolong use of chewing gums reduced stimulated and unstimulated saliva flow. Frequent use of chewing gums with carbamide provoked increased activity of ureapositive oral microflora. Degree of alkaline changes of mixed saliva pH in case of 3-month use of chewing gums Orbit and Stimorol pro Z was reduced. Chewing gums had weak hygienic efficacy.
authors.forename: V A
authors.initials: VA
authors.lastname: Rumiantsev
authors.forename: I V
authors.initials: IV
authors.lastname: Namestnikova
authors.forename: V I
authors.initials: VI
authors.lastname: Mitrofanov
authors.forename: E M
authors.initials: EM
authors.lastname: Zakulenkova
mesh_terms: D000328:Adult; D002182:Candy; D002638:Chewing Gum; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D009055:Mouth / Q000187:drug effects* / Q000382:microbiology; D009910:Oral Hygiene; D012463:Saliva / Q000737:chemistry; D012472:Salivation / Q000187:drug effects; D013395:Sucrose / Q000494:pharmacology*; D013549:Sweetening Agents / Q000494:pharmacology*
chemical_list: D002638:Chewing Gum; D013549:Sweetening Agents; D013395:Sucrose