title: Cofactor regeneration at the lab scale.
abstract: Progress made in lab-scale applications of various coenzyme regeneration systems over the last two decades has mainly focused on the applications of NAD+/NADH- and NADP+/NADPH-dependent oxidoreductase reactions. In situ regeneration systems for these reactions, as well as whole cell, enzymatic, electro-enzymatic, chemical, and photochemical reactions are presented, including details about their efficiency and novelty. The progress of enzyme reaction engineering is also reported.
authors.affiliation: Biochemical Engineering Group, Department of Biochemical and Chemical Engineering, Universität Dortmund, 44221 Dortmund, Germany. wichmann@bci.uni-dortmund.de
authors.forename: R
authors.initials: R
authors.lastname: Wichmann
authors.forename: D
authors.initials: D
authors.lastname: Vasic-Racki
mesh_terms: D019149:Bioreactors; D001709:Biotechnology / Q000295:instrumentation / Q000379:methods*; D003067:Coenzymes / Q000737:chemistry* / Q000378:metabolism*; D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods*; D004793:Enzyme Reactivators / Q000737:chemistry; D010777:Photochemistry / Q000295:instrumentation / Q000379:methods*; D010865:Pilot Projects
chemical_list: D003067:Coenzymes; D004793:Enzyme Reactivators