Enantioselective acylation of secondary alcohols catalyzed by chiral N-heterocyclic carbenes.
[reaction: see text] The synthetic utility of chiral N-heterocyclic carbenes, which have been used mainly in transition metal-catalyzed reactions as a ligand, was demonstrated by the enantioselective acylation of secondary alcohols.
Kano
Taichi
T
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.
Sasaki
Kouji
K
Maruoka
Keiji
K