title: Advances in evaluation and management of gastrinoma in patients with Zollinger-Ellison syndrome.
abstract: Gastrinomas producing Zollinger-Ellison syndrome are the most frequent symptomatic, malignant pancreatic endocrine tumor syndrome. Recently, a number of important studies have examined their molecular pathogenesis and natural history and provided important guidelines for their treatment. Each of these areas is briefly reviewed in this article.
authors.affiliation: Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-1804, USA.
authors.forename: Fathia
authors.initials: F
authors.lastname: Gibril
authors.forename: Robert T
authors.initials: RT
authors.lastname: Jensen
mesh_terms: D015408:Gastrinoma / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D010190:Pancreatic Neoplasms / Q000473:pathology / Q000628:therapy*; D011379:Prognosis; D015043:Zollinger-Ellison Syndrome / Q000628:therapy*