title: [The investigation on basic contents of organochlorine pesticides in human milk during consecutive periods in Beijing urban areas].
abstract: OBJECTIVE
  To investigate the basic contents of organochlorine pesticides (DDT, BHC and HCB) in human milk of normal residents in Beijing urban areas.
  
  
  METHODS
  Through continuous survey on the trend of organochlorine contents in human milk since DDT and BHC pesticides were forbidden in use in 1983, and to evaluate the effects of this program, the required lying-in women residents in urban districts for at least 5 years were enrolled in this study. All these lying-in women and also their family members were not exposed to or engaged in producing or selling organochlorine pesticides. In this study, the women chosen were giving birth to a child just after one week to 4 months. The detection method used is the national standard biological detection method.
  
  
  RESULTS
  In 1982, the total amount of DDT and BHC contents in human milk were 6.45 mg/kg and 6.97 mg/kg, respectively, which were found the highest level in the word. The contents of organochlorine were descending apparently since the DDT and BHC pesticides were forbidden by Chinese government in 1983. According to the standards of FAO/WHO, the average intake of total DDT and beta-BHC in the infants born in 1998 was 11 and 6 microg/kg, respectively. Both of them were less than the allowable daily intake amount regulated by WHO and the Ministry of Health of Japan.
  
  
  CONCLUSIONS
  The study might make clear that the basic levels of organochlorine pesticides (DDT, BHC and HCB) in human milk of normal residents and the attenuation trend of 2 pesticides cumulative levels in human body, through estimating the intake quantity of organochlorine by infants, showing that the DDT and BHC daily intake from human milk absorbed by infants, who were born after 1998, were at a safe level. It was indicated that the measure for forbidding use of DDT and BHC pesticides is contributory.
authors.affiliation: Institute of Environmental Health, Beijing Center for Diseases Prevention and Control, Beijing 100013, China.
authors.forename: Hui-fang
authors.initials: HF
authors.lastname: Yu
authors.forename: Xu-dong
authors.initials: XD
authors.lastname: Zhao
authors.forename: Xiao-ming
authors.initials: XM
authors.lastname: Zhang
authors.forename: Zhi-qin
authors.initials: ZQ
authors.lastname: Zhu
authors.forename: Zhu
authors.initials: Z
authors.lastname: Zhao
mesh_terms: D000328:Adult; D002681:China; D003634:DDT / Q000032:analysis; D005260:Female; D006581:Hexachlorobenzene / Q000032:analysis; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis*; D008895:Milk, Human / Q000737:chemistry*; D010573:Pesticide Residues / Q000032:analysis*; D014504:Urban Health
chemical_list: D006843:Hydrocarbons, Chlorinated; D010573:Pesticide Residues; D006581:Hexachlorobenzene; D003634:DDT