title: Pre-emptive effects of ibuprofen syrup and lidocaine infiltration on post-operative analgesia in children undergoing adenotonsillectomy.
abstract: We aimed to compare the effects of lidocaine and adrenaline with ibuprofen syrup (administered before adenotonsillectomy) on post-operative analgesia and initiation of oral feeding. One group of 20 children received 100 g/5 ml ibuprofen suspension (10 mg/kg) 1 h before anaesthesia; bleeding control was provided by pre-incisional administration of 1:200,000 adrenaline solution (10 ml). The same amount of 0.5% lidocaine solution plus 1:200,000 adrenaline was applied pre-incisionally in a similar manner in a second group of 20 children. No significant differences were observed between the two groups in terms of the duration of operation and anaesthesia, post-operative pain scores, paracetamol requirements, times to initiation of liquid and solid food intake, or adverse side-effects. We conclude that ibuprofen syrup applied pre-incisionally and local infiltration with lidocaine are equally effective for post-operative analgesia.
authors.affiliation: Department of Anesthesiology and Reanimation, Ege University Hospital, Bornova, Izmir, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Kedek
authors.forename: A
authors.initials: A
authors.lastname: Derbent
authors.forename: M
authors.initials: M
authors.lastname: Uyar
authors.forename: C
authors.initials: C
authors.lastname: Bilgen
authors.forename: M
authors.initials: M
authors.lastname: Uyar
authors.forename: T
authors.initials: T
authors.lastname: Kirazli
authors.forename: A
authors.initials: A
authors.lastname: Certug
mesh_terms: D000233:Adenoidectomy / Q000379:methods*; D000284:Administration, Oral; D000698:Analgesia; D018712:Analgesics, Non-Narcotic / Q000494:pharmacology; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000494:pharmacology*; D008012:Lidocaine / Q000494:pharmacology*; D008297:Male; D010146:Pain; D010149:Postoperative Pain / Q000517:prevention & control*; D013997:Time Factors; D014068:Tonsillectomy / Q000379:methods*
chemical_list: D018712:Analgesics, Non-Narcotic; D000779:Anesthetics, Local; D008012:Lidocaine; D007052:Ibuprofen; D004837:Epinephrine