Synthesis and water solubility of adamantyl-OEG-fullerene hybrids.
[reaction: see text] A series of new adamantyl-oligoethyleneglycol-fullerene hybrids was prepared via Bingel-Hirsch functionalization of the C60 fullerene with various adamantyl-oligoethyleneglycol malonates. As NMDA-targeted antioxidants, these compounds may have the potential to be developed as therapeutic agents for the treatment of neurological disorders.
Bar-Shir
Amnon
A
School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Engel
Yoni
Y
Gozin
Michael
M
D000218:Adamantane / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry; D037741:Fullerenes / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry / Q000379:methods; D012995:Solubility; D014867:Water
D037741:Fullerenes; C500477:adamantyl-OEG-fullerene; D014867:Water; D000218:Adamantane