title: Erectile dysfunction and its influence on quality of life in patients with essential hypertension.
abstract: Epidemiological studies indicated that erectile dysfunction (ED) is more frequent and their quality of life (QOL) is deteriorated in patients with essential hypertension as compared with normotensive subjects. Since both ED and hypertension influence QOL, it is not clear which malady has a more serious influence on QOL. We conducted a case control study to investigate incidence and impact of ED on QOL. In 102 patients aged 40 to 59 under treatment for hypertension (Hypertensive group) and in 245 age-matched normal subjects (Control group), QOL and ED were assessed by SF-36 and IIEF5. Criteria for presence of ED is IIEF5 score less than 12. Age adjusted incidence of ED in Hypertension group was higher than that in Control Group (odds ratio 1.7, P < .05). Multivariate logistic regression analysis showed hypertension was related only to a low score in general health, ED was related to low scores in physical, mental health, emotional, vitality, and general health. These data suggest that the influence of ED on QOL is more serious than hypertension in middle age men.
authors.affiliation: Department of Cardiology, Nihon University Surugadai Hospital, 1-8-13 Kandasurugadai Chiyoda-ku, Tokyo 101-8309, Japan. kushiro@med.nihon-u.ac.jp
authors.forename: Toshio
authors.initials: T
authors.lastname: Kushiro
authors.forename: Atsuhiko
authors.initials: A
authors.lastname: Takahashi
authors.forename: Fumio
authors.initials: F
authors.lastname: Saito
authors.forename: Yuji
authors.initials: Y
authors.lastname: Otsuka
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Soma
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Kurihara
authors.forename: Atsushi
authors.initials: A
authors.lastname: Satomura
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Saito
authors.forename: Katsuo
authors.initials: K
authors.lastname: Kanmatsuse
mesh_terms: D000328:Adult; D017677:Age Distribution; D000959:Antihypertensive Agents / Q000008:administration & dosage; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D007172:Erectile Dysfunction / Q000453:epidemiology* / Q000523:psychology*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000453:epidemiology* / Q000523:psychology*; D015994:Incidence; D008297:Male; D015995:Prevalence; D011788:Quality of Life; D011795:Surveys and Questionnaires
chemical_list: D000959:Antihypertensive Agents