Supramolecular structures of three isomeric 2-chloro-N-(nitrophenyl)nicotinamides.
Molecules of 2-chloro-N-(2-nitrophenyl)nicotinamide, C12H8ClN3O3, are linked by two C-H...O hydrogen bonds into a chain of edge-fused R(2)(2) (14) and (4)(4) (24) rings. In 2-chloro-N-(3-nitrophenyl)nicotinamide monohydrate, C12H8ClN3O3.H2O, the molecules are linked by a combination of N-H...O, O-H...O and O-H...N hydrogen bonds into a chain of edge-fused rings containing two distinct types of R(4)(4) (16) ring. In 2-chloro-N-(4-nitrophenyl)nicotinamide, C12H8ClN3O3, which crystallizes with Z' = 2 in space group P2(1)/n, the molecules are linked by two N-H...N hydrogen bonds into simple C(2)(2) (12) chains.
de Souza
Marcus V N
MV
Complexo Tecnológico de Medicamentos Farmanguinhos, Av. Comandante Guaranys 447, Jacarepaguá, Rio de Janeiro, RJ, Brazil.
Vasconcelos
Thatyana R A
TR
Wardell
Solange M S V
SM
Wardell
James L
JL
Low
John N
JN
Glidewell
Christopher
C
D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D007536:Isomerism; D015394:Molecular Structure; D009536:Niacinamide / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry
D009536:Niacinamide