title: Mitral valve replacement in a patient with severe thrombophilic status and direct antiglobulin test positivity: case report.
abstract: The case is reported of a patient with a symptomatic thrombophilic status and a positivity for both direct and indirect antiglobulin tests who underwent mitral valve replacement. Because of the antiglobulin test positivity, the patient was enrolled in a preoperative autologous blood donation program in order to avoid exposure to allogenic blood. The operation was successful, and the postoperative course uneventful; the patient was discharged on postoperative day 6 and prescribed oral anticoagulation. This case suggests that a safe valve replacement can be carried out even in the presence of a symptomatic thrombophilic preoperative status.
authors.affiliation: Interdisciplinary Center for Biomedical Research (CIR), Università Campus Bio-Medico, Rome, Italy. S.Mastrobuoni@unicampus.it
authors.forename: Stefano
authors.initials: S
authors.lastname: Mastrobuoni
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Avvisati
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Tirindelli
authors.forename: Massimo
authors.initials: M
authors.lastname: Migliaccio
authors.forename: Massimo
authors.initials: M
authors.lastname: Chello
authors.forename: Elvio
authors.initials: E
authors.lastname: Covino
mesh_terms: D000328:Adult; D003298:Coombs Test; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000150:complications* / Q000601:surgery*; D012720:Severity of Illness Index; D019851:Thrombophilia / Q000150:complications*