title: [Primary meningeal intermediate grade melanocytic neoplasm: case report with radiologic-pathologic correlation].
abstract: A case of primary meningeal intermediate grade melanocytic neoplasm involving the right C2 nerve root is presented. MRI findings may suggest this rare entity, especially when an extra-axial lesion is located in the posterior fossa or cervical spinal canal and demonstrates shortening of both T1 and T2. Eventually, definitive diagnosis relies on histology which demonstrates spindle-shaped melanocytic cells that are Fontana stained and positive for HMB:45 antigen. Cellularity, pleomorphism, mitotic rate, proliferation index and invasiveness are useful criteria to distinguish among the spectrum of primary melanocytic tumors of the central nervous system ranging from melanocytoma to malignant melanoma.
authors.affiliation: Service de Radiologie 2, Hôpital de Hautepierre, avenue Molière, 67098 Strasbourg Cedex. moser_th@yahoo.fr
authors.forename: T
authors.initials: T
authors.lastname: Moser
authors.forename: T S
authors.initials: TS
authors.lastname: Nogueira
authors.forename: W
authors.initials: W
authors.lastname: Fakhoury
authors.forename: N
authors.initials: N
authors.lastname: Pfleger
authors.forename: A
authors.initials: A
authors.lastname: Neuville
authors.forename: P
authors.initials: P
authors.lastname: Kehrli
authors.forename: R
authors.initials: R
authors.lastname: Beltechi
authors.forename: A
authors.initials: A
authors.lastname: Serban
authors.forename: R
authors.initials: R
authors.lastname: Silvestre
authors.forename: J L
authors.initials: JL
authors.lastname: Dietemann
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008545:Melanoma / Q000175:diagnosis* / Q000473:pathology; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed