title: Poland-Möbius syndrome and cocaine abuse: a relook at vascular etiology.
abstract: This report presents a severe case of Poland-Möbius syndrome with central apnea at birth, ventilator-dependent, and with brainstem calcifications. The newborn had unilateral defect of the right pectoralis muscle, breast, and limb. He manifested bilateral paralysis of the cranial nerves resulting in shallow respiration, apnea, and dysphagia. He finally required tracheostomy and gastrostomy. Maternal history revealed multiple uses of cocaine during the first 3 months of pregnancy. The patient supports the Poland-Möbius combination and the possibility of vascular disruption sequence.
authors.affiliation: Department of Pediatrics, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07302, USA.
authors.forename: Surasak
authors.initials: S
authors.lastname: Puvabanditsin
authors.forename: Eugene
authors.initials: E
authors.lastname: Garrow
authors.forename: Gerda
authors.initials: G
authors.lastname: Augustin
authors.forename: Ruetima
authors.initials: R
authors.lastname: Titapiwatanakul
authors.forename: Katherine M
authors.initials: KM
authors.lastname: Kuniyoshi
mesh_terms: D001933:Brain Stem / Q000098:blood supply* / Q000473:pathology; D002114:Calcinosis / Q000209:etiology / Q000473:pathology; D019970:Cocaine-Related Disorders / Q000150:complications* / Q000473:pathology; D003391:Cranial Nerves / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D020331:Mobius Syndrome / Q000209:etiology* / Q000473:pathology; D011045:Poland Syndrome / Q000209:etiology* / Q000473:pathology