Helicobacter pylori in children who are prone to upper respiratory tract infections.
OBJECTIVE
To examine the presence of Helicobacter pylori infection in children with recurrent upper respiratory infections, including acute otitis media.


METHODS
A prospective clinical trial.


METHODS
Tertiary referral center.


METHODS
A total of 20 children who were prone to upper respiratory infections and acute otitis and who were admitted for elective adenoidectomy and/or tympanostomy were included in the study.


METHODS
Samples of adenoid tissue and middle ear fluid were cultured for H pylori. Serologic analysis and fecal antigen detection testing were also carried out to determine the presence of H pylori.


RESULTS
The results of serologic and antigen detection tests were positive for H pylori in 4 children (20%), but cultures of adenoid tissue and middle ear fluid samples were negative for H pylori in all children.


CONCLUSIONS
An association between H pylori infection and recurrent upper respiratory infections and otitis media could not be established.
Pitkäranta
Anne
A
Department of Otorhinolaryngology, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland. anne.pitkaranta@hus.fi
Kolho
Kaija-Leena
KL
Rautelin
Hilpi
H
D000208:Acute Disease; D000233:Adenoidectomy / Q000379:methods; D017677:Age Distribution; D000942:Antigens, Bacterial / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D004198:Disease Susceptibility; D005243:Feces / Q000382:microbiology; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000453:epidemiology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D015994:Incidence; D008297:Male; D008876:Middle Ear Ventilation / Q000379:methods; D010033:Otitis Media / Q000453:epidemiology / Q000382:microbiology* / Q000601:surgery; D011379:Prognosis; D011446:Prospective Studies; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000382:microbiology*; D012307:Risk Factors; D017678:Sex Distribution
D000942:Antigens, Bacterial