title: Constituents of holothuroidea, 14. Isolation and structure of new glucocerebroside molecular species from the sea cucumber Stichopus japonicus.
abstract: Five glucocerebroside molecular species, SJC-1-SJC-5, have been isolated from the less polar lipid fraction of a chloroform/methanol extract of the sea cucumber Stichopus japonicus. The structures of these glucocerebroside molecular species were determined on the basis of chemical and spectroscopic evidence. SJC-1, SJC-2, and SJC-3 are typical sphingosine- and phytosphingosine-type glucocerebroside molecular species with nonhydroxylated and hydroxylated fatty acyl moieties. SJC-4 and SJC-5 are also sphingosine-type glucocerebroside molecular species with hydroxylated fatty acyl moieties, although they are new glucocerebroside molecular species with unique sphingosine bases.
authors.affiliation: Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka.
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Kisa
authors.forename: Koji
authors.initials: K
authors.lastname: Yamada
authors.forename: Masafumi
authors.initials: M
authors.lastname: Kaneko
authors.forename: Masanori
authors.initials: M
authors.lastname: Inagaki
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Higuchi
mesh_terms: D000818:Animals; D008401:Gas Chromatography-Mass Spectrometry; D005963:Glucosylceramides / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D000432:Methanol; D008968:Molecular Conformation; D012616:Sea Cucumbers / Q000737:chemistry*; D012997:Solvents; D013055:Spectrophotometry, Infrared
chemical_list: D005963:Glucosylceramides; D012997:Solvents; D000432:Methanol