title: [Effect of vitamin-mineral supplementation on the status of some microelements in pregnant women].
abstract: We studied the effect of VIBOVITmama (Polfa Kutno S.A.) supplementation on the course of pregnancy duration, delivery and puerperium and also the status of zinc, copper and selenium in the blood of matched maternal-cord pairs. Healthy pregnant women (n=138) were divided by a double blinded trial into a test group taking vitamin and mineral supplementation containing 15 mg of zinc, 2 mg of copper and 20 microg of selenium and a control group taking placebo. Course of pregnancy, delivery and puerperium were analyzed, as well as concentration of bioelements in the blood serum of pregnant women in the I, II, and II trimester and in umbilical cord blood of their children. In the study group we noted fewer by 1.45% cases of pregnancy induced hypertension and a much higher rate of natural deliveries (75%) in comparison to the control group (53%). During pregnancy in the supplemented group a 1% increase of zinc serum concentration was found. In the control group zinc concentration decreased by 7% (p < 0.005). Insignificant differences in serum concentration of copper and selenium was observed between the study group and controls. In umbilical cord blood the differences in the concentration of the above microelements were also insignificant. The results allow for the statement that VIBOVITmama supplementation stabilizes the zinc, copper and selenium levels in blood of pregnant women without the risk of overdosing, especially with reference to selenium.
authors.affiliation: Klinika Połoznictwa i Ginekologii Instytutu Matki i Dziecka, Warszawie.
authors.forename: Paweł
authors.initials: P
authors.lastname: Kubik
authors.forename: Bozena
authors.initials: B
authors.lastname: Kowalska
authors.forename: Teresa
authors.initials: T
authors.lastname: Laskowska-Klita
authors.forename: Magdalena
authors.initials: M
authors.lastname: Chełchowska
authors.forename: Jerzy
authors.initials: J
authors.lastname: Leibschang
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000378:metabolism*; D015415:Biomarkers / Q000097:blood; D003300:Copper / Q000097:blood; D004311:Double-Blind Method; D005260:Female; D005312:Fetal Blood / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D018977:Micronutrients / Q000008:administration & dosage / Q000097:blood*; D011044:Poland; D011247:Pregnancy / Q000097:blood*; D011248:Pregnancy Complications / Q000517:prevention & control; D011295:Prenatal Care / Q000379:methods; D012643:Selenium / Q000097:blood; D013997:Time Factors; D014131:Trace Elements / Q000008:administration & dosage / Q000097:blood*; D014815:Vitamins / Q000008:administration & dosage; D015032:Zinc / Q000097:blood
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D018977:Micronutrients; D014131:Trace Elements; D014815:Vitamins; D003300:Copper; D012643:Selenium; D015032:Zinc