title: Chromosomal replication and the cell membrane.
abstract: The importance of the cell membrane in bacterial chromosomal replication continues to emerge. Recent advances include better definition of the biochemical interaction between membrane acidic phospholipids and the replication initiator, DnaA protein, the physiological impact that an altered membrane lipid composition has on chromosomal replication and the identification and characterization of recently identified membrane-associated proteins that regulate replication and participate in chromosomal segregation.
authors.affiliation: Department of Biochemistry, Georgetown University Medical Center, 3900 Reservoir Road, Basic Science Building, Washington DC, 20007, USA.
authors.forename: Kelly
authors.initials: K
authors.lastname: Boeneman
authors.forename: Elliott
authors.initials: E
authors.lastname: Crooke
mesh_terms: D018407:Bacterial Physiological Phenomena; D001426:Bacterial Proteins / Q000378:metabolism*; D002462:Cell Membrane / Q000502:physiology*; D002876:Chromosomes, Bacterial / Q000378:metabolism*; D004261:DNA Replication; D004268:DNA-Binding Proteins / Q000378:metabolism*; D018741:Replication Origin / Q000502:physiology
chemical_list: D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; C066312:DnaA protein, Bacteria