title: GandrKB--ontological microarray annotation and visualization.
abstract: The Gandr (gene annotation data representation) knowledgebase is an ontological framework for laboratory-specific gene annotation. Gandr uses Protege 2000 for editing, querying and visualizing microarray data and annotations. Genes can be annotated with provided, newly created or imported ontological concepts. Annotated genes can inherit assigned concept properties and can be related to each other. The resulting knowledgebase can be visualized as interactive network of nodes and edges representing genes and their functional relationships. This allows for immediate and associative gene context exploration. Ontological query techniques allow for powerful data access.
authors.affiliation: Department for Bioinformatics, Max Delbrück Center for Molecular Medicine, D-13122 Berlin, Germany. schober@mdc-berlin.de
authors.forename: Daniel
authors.initials: D
authors.lastname: Schober
authors.forename: Ulf
authors.initials: U
authors.lastname: Leser
authors.forename: Martin
authors.initials: M
authors.lastname: Zenke
authors.forename: Jens
authors.initials: J
authors.lastname: Reich
mesh_terms: D000465:Algorithms; D003196:Computer Graphics; D004282:Documentation / Q000379:methods; D020869:Gene Expression Profiling / Q000379:methods*; D005786:Gene Expression Regulation / Q000502:physiology*; D008954:Models, Biological; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D010802:Phylogeny; D015398:Signal Transduction / Q000502:physiology; D012984:Software; D014584:User-Computer Interface