Adding specificity to artificial transcription activators.
In this issue, Mapp and colleagues describe a significant advance in the design of artificial transcription activators that function in a cell-type-specific manner. [1] The authors show that peptides selected for binding a component of the yeast transcription complex require its presence for effective transcriptional activation.
Arora
Paramjit S
PS
Department of Chemistry, New York University, New York, NY 10012, USA.
D015966:Gene Expression Regulation, Fungal; D015534:Trans-Activators / Q000138:chemical synthesis* / Q000737:chemistry* / Q000235:genetics
D015534:Trans-Activators