title: Na(+)-Translocating NADH:quinone oxidoreductase: progress achieved and prospects of investigations.
abstract: Structural and catalytic properties of bacterial Na+-translocating NADH:quinone oxidoreductases are briefly described. Special attention is given to studies on kinetics of the enzyme interaction with NADH and the role of sodium ions in this process. Based on the existing data, possible model mechanisms of sodium transfer by Na+-translocating NADH:quinone oxidoreductase are proposed.
authors.affiliation: Department of Molecular Energetics of Microorganisms, Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119992, Russia. sodiumc@genebee.msu.ru
authors.forename: A V
authors.initials: AV
authors.lastname: Bogachev
authors.forename: M I
authors.initials: MI
authors.lastname: Verkhovsky
mesh_terms: D001426:Bacterial Proteins / Q000737:chemistry / Q000502:physiology*; D002384:Catalysis; D008954:Models, Biological; D010084:Oxidation-Reduction; D011808:Quinone Reductases / Q000737:chemistry / Q000502:physiology*; D014733:Vibrio / Q000201:enzymology
chemical_list: D001426:Bacterial Proteins; C084142:sodium-translocating NADH-quinone reductase; D011808:Quinone Reductases