Detection of combined hepatocellular and cholangiocarcinomas on enhanced CT: comparison with histologic findings.
OBJECTIVE
The purpose of this study was to evaluate the performance of enhanced CT in making a diagnosis of combined hepatocellular and cholangiocarcinomas (HCC-CCs) by comparing CT findings with histologic findings.


CONCLUSIONS
One third (nine of 27 cases) of the combined HCC-CCs were correctly diagnosed on enhanced CT by detailed analysis of the enhancing pattern around or within the mass. Various factors such as an atypical enhancing pattern, the size of each component, and the presence of a mass composed of intermediate tumor cells-that is, cells with intermediate characteristics between HCC and CC-were found to be the causes of misdiagnosis of combined HCC-CC on enhanced CT.
Nishie
Akihiro
A
Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku Fukuoka 812-8582, Japan. anishie@radiol.med.kyushuu.ac.jp
Yoshimitsu
Kengo
K
Asayama
Yoshiki
Y
Irie
Hiroyuki
H
Aibe
Hitoshi
H
Tajima
Tsuyoshi
T
Shinozaki
Kenji
K
Nakayama
Tomohiro
T
Kakihara
Daisuke
D
Shimada
Mitsuo
M
Aishima
Shin-Ichi
S
Yoshida
Kisaku
K
Honda
Hiroshi
H
D000328:Adult; D000368:Aged; D001650:Bile Duct Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D001653:Bile Ducts, Intrahepatic / Q000000981:diagnostic imaging* / Q000473:pathology; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging* / Q000473:pathology; D018281:Cholangiocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D003287:Contrast Media; D005260:Female; D006801:Humans; D007479:Iopamidol; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods*
D003287:Contrast Media; D007479:Iopamidol