title: Community-acquired pneumonia and sepsis.
abstract: Sepsis is a frequent and often fatal complication of pneumonia. This article discusses the epidemiology, pathophysiology, and treatment of sepsis in the setting of pneumonia. Particular consideration is given to the role of mechanical ventilation in amplifying organ dysfunction in sepsis and to treatments that have positive effects on sepsis mortality and respiratory dysfunction.
authors.affiliation: Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center, Campus Box C272, 4200 East Ninth Avenue, Denver, CO 80262, USA. michelle.beutz@uchsc.edu
authors.forename: Michelle A
authors.initials: MA
authors.lastname: Beutz
authors.forename: Edward
authors.initials: E
authors.lastname: Abraham
mesh_terms: D017714:Community-Acquired Infections / Q000150:complications / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D018410:Pneumonia, Bacterial / Q000150:complications / Q000503:physiopathology* / Q000628:therapy; D012307:Risk Factors; D018805:Sepsis / Q000401:mortality / Q000503:physiopathology* / Q000628:therapy*