title: [Postprandial lipemia in Colombian young adults from different ethnic groups].
abstract: Postprandial lipemia has been associated with atherogenesis and other non infectious chronic diseases. A descriptive, non aleatory study of 51 healthy young adults (23.8 +/- 4 years) of different ethnic background was carried out to identify possible personal or life style factors associated with the response of plasma lipids after a mixed carbohydrate and lipid load. Personal, family, life styles including use of drugs and activity and ethnic background were recorded. Anthropometrical measurements, a short insulin and postprandial lipemia tests were done. From these observations body mass index (BMI) and area under the curve (AUC) for lipids and glucose were calculated. High mean values were observed in AUC for glucose, triacylglycerol and nonesterified fatty acids (NEFA). Postprandial glucose with differences by age (p=0.05 Bonferroni) but no ethnic, gender, BMI or insulin sensitivity related significant differences were found. Mestizos (40%) showed two, and Negroes three (27%) postprandial triglyceridemia peaks. Noteworthy, subjects presenting four peaks had elevated BMI. Higher triglyceridemia values were found in white and mestizos (p<0.05), in subjects older than 29 and in males (p<0.05). Statistical correlation (r2=0.70) between BMI and triglyceridemia and change in postprandial trigliceridemia was found in white and black subjects. NEFA declined up to the second hour, but at 6-7 hours they reached levels higher than base values. Higher than reported values for UCA and BMI and an abnormal response to fat intake with an early release of NEFA was found. The high correlation between BMI and postprandial trigliceridemia suggests that body mass index could be a good predictor of postprandial trigliceridemia.
authors.affiliation: Departamento de Ciencias Fisiológicas, Universidad del Valle, Colombia.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Aguilar de Plata
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Velasco de Echeverri
authors.forename: Beatriz
authors.initials: B
authors.lastname: Gracia de Ramírez
authors.forename: Alberto
authors.initials: A
authors.lastname: Pradilla Ferreira
authors.forename: Martha Liliana
authors.initials: ML
authors.lastname: Cruz Naranjo
authors.forename: Mildrey
authors.initials: M
authors.lastname: Mosquera Escudero
mesh_terms: D000328:Adult; D019540:Area Under Curve; D001786:Blood Glucose / Q000378:metabolism; D002791:Cholesterol, Dietary / Q000378:metabolism*; D003105:Colombia / Q000208:ethnology; D004040:Dietary Carbohydrates / Q000378:metabolism*; D005006:Ethnicity; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D019518:Postprandial Period / Q000502:physiology*; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D002791:Cholesterol, Dietary; D004040:Dietary Carbohydrates; D005230:Fatty Acids, Nonesterified; D008055:Lipids; D014280:Triglycerides