title: Conjunctival biopsy of anophthalmic socket in sarcoidosis.
abstract: A case of sarcoidosis was diagnosed by a random conjunctival biopsy from an anophthalmic socket. A 22-year-old black female patient presented with anterior and posterior uveitis and subconjunctival nodules in the left eye. Her right eye was enucleated due to a penetrating injury 3 years before admission. Biopsy of subconjunctival nodules in the left eye failed to demonstrate granulomatous inflammation; however, a random conjunctival biopsy from the normal-appearing anophthalmic socket conjunctiva revealed noncaseating granulomas. Conjunctival biopsy is a safe, cost-effective means of diagnosis in sarcoidosis suspects. To our knowledge, this is the first reported case of sarcoidosis confirmed with random conjunctival biopsy from an anophthalmic socket.
authors.affiliation: Department of Ophthalmology, Tulane University Health Sciences Center, New Orleans, Louisiana 70112-2699, USA.
authors.forename: David M
authors.initials: DM
authors.lastname: Hinkle
authors.forename: Zeynel A
authors.initials: ZA
authors.lastname: Karcioglu
mesh_terms: D000328:Adult; D000853:Anophthalmos / Q000473:pathology*; D001706:Biopsy; D003228:Conjunctiva / Q000473:pathology*; D003229:Conjunctival Diseases / Q000175:diagnosis*; D015353:Eye Enucleation; D015807:Eye Injuries, Penetrating / Q000601:surgery; D005260:Female; D006801:Humans; D012507:Sarcoidosis / Q000175:diagnosis*; D017565:Sarcoidosis, Pulmonary / Q000175:diagnosis