Phenytoin hypersensitivity syndrome masquerading as fever and systemic illness of unknown origin in an HIV-infected patient.
A 32-year-old HIV-infected woman developed fever and systemic illness of unknown origin after being placed on phenytoin for seizures. Her clinical syndrome, skin biopsy findings, and clinical response to steroids were consistent with phenytoin hypersensitivity syndrome.
Bedimo
R J
RJ
UAB STD Program, Department of Medicine, University of Alabama at Birmingham, 703 19th Street South, 242 Zeigler Research Building, Birmingham, AL 35294-0007, USA.
Geisler
W M
WM
D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000150:complications*; D005260:Female; D005335:Fever of Unknown Origin / Q000209:etiology*; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D010672:Phenytoin / Q000009:adverse effects*
D000927:Anticonvulsants; D010672:Phenytoin