title: ANCA-associated renal vasculitis--epidemiology, diagnostics and treatment.
abstract: The pauciimmune small-vessel vasculitides are multisystem diseases with frequent renal involvement. They are strongly associated with the presence of anti-neutrophil cytoplasmic antibodies (ANCA). In this review we have focused on the ethiopathogenesis and the role of ANCA, clinical presentation and histopathologic findings of different ANCA - associated vasculitides (AAV). Current treatment strategies and the overall and renal outcome of patients with AAV are also discussed.
authors.affiliation: Nephrology Department of the First Faculty of Medicine, Charles University in Prague, Czech Republic. zrihova@seznam.cz
authors.forename: Z
authors.initials: Z
authors.lastname: Ríhová
authors.forename: E
authors.initials: E
authors.lastname: Jancová
authors.forename: M
authors.initials: M
authors.lastname: Merta
authors.forename: V
authors.initials: V
authors.lastname: Tesar
mesh_terms: D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis*; D015267:Churg-Strauss Syndrome / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D014657:Vasculitis / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic