Bilateral testicular tumors in an infertile man previously treated with follicle-stimulating hormones.
A 43-year-old infertile man with oligozoospermia and normal serum gonadotropin and cytogenetic findings was treated with follicle-stimulating hormone for 1 year at our institution. Two years later, the patient presented with bilateral palpable testicular tumors. His beta-human chorionic gonadotropin and lactate dehydrogenase levels were elevated. Pathologic examination disclosed a pure seminoma in each testis (pT1N0M0). Adjuvant radiotherapy was administered. The tumors might have been induced by follicle-stimulating hormone treatment. Careful follow-up examination of the testis is necessary in men who have received hormonal treatment for infertility.
Fukagai
Takashi
T
Department of Urology, Showa University School of Medicine, Tokyo, Japan. fukagai@attglobal.net
Kurosawa
Kazuhiro
K
Sudo
Naoki
N
Aso
Takayuki
T
Sugawara
So
S
Naoe
Michio
M
Sakamoto
Hideo
H
Yoshida
Hideki
H
D000328:Adult; D005640:Follicle Stimulating Hormone / Q000009:adverse effects*; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy*; D008297:Male; D018239:Seminoma / Q000139:chemically induced*; D013736:Testicular Neoplasms / Q000139:chemically induced*
D005640:Follicle Stimulating Hormone