Triol protection with 6-benzoyl-3,4-dihydro-(2H)-pyran.
6-Benzoyl-3,4-dihydro-(2H)-pyran will protect 1,2,3-triols such as glycerol as their corresponding spiro-[5-phenyl-3,6,8-trioxabicyclo[3.2.1]octane-4,2[prime or minute]-tetrahydropyran]s and 1,2,4-triols (less efficiently) as the corresponding trioxabicyclo[3.2.2]nonanes; the hexol mannitol is converted into the corresponding bis-protected product.
Baker
Caroline D L
CD
Department of Chemistry, University of Leicester, University Road, Leicester, UK.
Fawcett
John
J
Insley
Christopher D
CD
Messenger
Derek S
DS
Newland
Claire L
CL
Overend
Helen L
HL
Patel
Anup B
AB
Shah
Mufakhrul
M
Vara
Bhavna
B
Virdee
Davinder
D
Rawlings
Bernard J
BJ