title: [Anaesthesia in patients with Parkinson's disease].
abstract: The neurodegenerative death of dopaminergic neurons of the pars compacta of the substantia nigra leads to the classical triad of resting tremor, muscle rigidity, and bradykinesia of Parkinson's disease. Parkinson's disease is a common disease of elderly patients requiring perioperative anaesthesia. Particular anaesthetic problems are neurological, respiratory, and cardiovascular. The clinical features and the interaction of common anaesthetics with the drug therapy of the patient present an anaesthetic challenge and directly influence perioperative morbidity and mortality.
authors.affiliation: Institut für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Mannheim. armin.kalenka@urz.uni-hd.de
authors.forename: A
authors.initials: A
authors.lastname: Kalenka
authors.forename: J
authors.initials: J
authors.lastname: Hinkelbein
mesh_terms: D000368:Aged; D000758:Anesthesia / Q000009:adverse effects; D000769:Anesthesia, Inhalation; D000771:Anesthesia, Intravenous; D000777:Anesthetics / Q000009:adverse effects; D000978:Antiparkinson Agents / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D019635:Neurosurgical Procedures; D010300:Parkinson Disease / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology
chemical_list: D000777:Anesthetics; D000978:Antiparkinson Agents