title: Vaccines for otitis media: proposals for overcoming obstacles to progress.
abstract: Otitis media is a common problem with enormous morbidity worldwide. The development of vaccines to prevent otitis media would have an important human and economic impact. A striking lack of progress in the development, production and clinical testing of vaccines to prevent otitis media has occurred in the past decade. This review outlines a series of specific proposals intended to advance vaccine development for otitis media.
authors.affiliation: Division of Infectious Diseases, Department of Medicine, University at Buffalo, SUNY, USA. murphyt@buffalo.edu
authors.forename: Timothy F
authors.initials: TF
authors.lastname: Murphy
authors.forename: Lauren O
authors.initials: LO
authors.lastname: Bakaletz
authors.forename: Jennelle M
authors.initials: JM
authors.lastname: Kyd
authors.forename: Bracie
authors.initials: B
authors.lastname: Watson
authors.forename: David L
authors.initials: DL
authors.lastname: Klein
mesh_terms: D001428:Bacterial Vaccines / Q000276:immunology*; D002986:Clinical Trials as Topic; D006801:Humans; D009305:Nasopharynx / Q000382:microbiology; D010033:Otitis Media / Q000517:prevention & control*; D014611:Vaccination; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D001428:Bacterial Vaccines; D014765:Viral Vaccines