Organic and psychogenic factors leading to executive dysfunctions in a patient suffering from surgery of a colloid cyst of the Foramen of Monro.
The authors report a 41-year-old female patient who had suffered from colloid cyst of the Foramen of Monro. After surgical intervention in which the cyst was completely removed, her hydrocephalus decreased to normal ventricle size measured by MRI. However, the patient became depressive and reported vast difficulties in everyday life decision-making. An examination twenty months after surgery indicated psychiatric symptoms and abnormalities in personality. Neuropsychological investigation revealed average to above average performance in anterograde memory, attention, information processing, and intelligence. In contrast, the patient was severely impaired in decision-making, complex executive functions, and social cognition. In 18F-2-fluoro-2-deoxy-D-glucose (18FDG-PET) hypometabolism in bilateral dorsolateral prefrontal cortex, cingulate cortex and left fusiform gyrus was observed. The authors conclude that in this case decision-making deficits and executive dysfunctions are influenced by both organic and psychogenic factors.
Brand
Matthias
M
Department of Physiological Psychology, University of Bielefeld, Bielefeld, Germany. m.brand@uni-bielefeld.de
Kalbe
Elke
E
Kracht
Lutz W
LW
Riebel
Ulrich
U
Münch
Jürgen
J
Kessler
Josef
J
Markowitsch
Hans J
HJ
D000328:Adult; D001927:Brain Diseases / Q000601:surgery*; D002552:Cerebral Ventricles / Q000601:surgery*; D003071:Cognition / Q000502:physiology; D003560:Cysts / Q000601:surgery*; D004644:Emotions / Q000502:physiology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D009422:Nervous System Diseases / Q000209:etiology* / Q000523:psychology* / Q000534:rehabilitation; D009483:Neuropsychological Tests; D019635:Neurosurgical Procedures / Q000009:adverse effects*; D049268:Positron-Emission Tomography; D011183:Postoperative Complications / Q000523:psychology* / Q000534:rehabilitation; D011597:Psychomotor Performance / Q000502:physiology; D019275:Radiopharmaceuticals; D012919:Social Behavior
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18