title: Fright is a provoking factor in vanishing white matter disease.
abstract: Leukoencephalopathy with vanishing white matter is an inherited disorder with a chronic progressive disease course and additional episodes of rapid neurological deterioration. These episodes typically are provoked by febrile infections or minor head trauma. We report on two patients who experienced an episode of rapid neurological deterioration after a fright.
authors.affiliation: Department of Pediatrics/Child Neurology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.
authors.forename: Gerre
authors.initials: G
authors.lastname: Vermeulen
authors.forename: Rainer
authors.initials: R
authors.lastname: Seidl
authors.forename: Saadet
authors.initials: S
authors.lastname: Mercimek-Mahmutoglu
authors.forename: Jan J
authors.initials: JJ
authors.lastname: Rotteveel
authors.forename: Gert C
authors.initials: GC
authors.lastname: Scheper
authors.forename: Marjo S
authors.initials: MS
authors.lastname: van der Knaap
mesh_terms: D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D002675:Child, Preschool; D005239:Fear / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011859:Radiography