title: Restricted expression of a median Hox gene in the central nervous system of chaetognaths.
abstract: Hox genes encode a set of evolutionarily conserved transcription factors that regulate anterior-posterior patterning. Here we report the first developmental expression of a Hox gene from Chaetognatha. These metazoans have been shown recently to be part of the protostome group of bilaterians. We describe the analysis of the SceMed4 gene (a Spadella cephaloptera Median Hox gene) including its expression from late stages of egg development to 7 days after hatching. In all of these stages, SceMed4 is expressed in two lateral stripes in a restricted region of the developing ventral ganglion.
authors.affiliation: Centre d'Océanologie de Marseille, UMR 6540 CNRS DIMAR, Marseille, France. papillon@com.univ-mrs.fr
authors.forename: Daniel
authors.initials: D
authors.lastname: Papillon
authors.forename: Yvan
authors.initials: Y
authors.lastname: Perez
authors.forename: Laurent
authors.initials: L
authors.lastname: Fasano
authors.forename: Yannick
authors.initials: Y
authors.lastname: Le Parco
authors.forename: Xavier
authors.initials: X
authors.lastname: Caubit
mesh_terms: D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D000818:Animals; D002490:Central Nervous System / Q000254:growth & development / Q000378:metabolism*; D004625:Embryo, Nonmammalian; D005727:Ganglia, Spinal / Q000196:embryology; D018507:Gene Expression Regulation, Developmental; D005801:Genes, Homeobox; D017403:In Situ Hybridization; D007448:Invertebrates / Q000145:classification / Q000196:embryology* / Q000235:genetics*; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid