The antimicrobial activity of extracts of the lichen Hypogymnia tubulosa and its 3-hydroxyphysodic acid constituent.
The antimicrobial activity and the MIC values of the diethyl ether, acetone, chloroform, petroleum ether, and ethanol extracts of the lichen Hypogymnia tubulosa and its 3-hydroxyphysodic acid constituent have been investigated against some microorganisms. At least one of the extracts or 3-hydroxyphysodic acid showed antimicrobial activity against Aeromonas hydrophila, Bacillus cereus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae, Listeria monocytogenes, Proteus vulgaris, Salmonella typhimurium, Staphylococcus aureus, Streptococcus faecalis, and Candida albicans. No antifungal activity of the extracts has been observed against ten filamentous fungi.
Yilmaz
Meral
M
Anadolu University, Department of Biology, 26470 Eskişehir, Turkey. mkivanc@anadolu.edu.tr
Tay
Turgay
T
Kivanç
Merih
M
Türk
Hayrettin
H
Türk
Ayşen Ozdemir
AO
D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D003990:Dibenzoxepins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008011:Lichens / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification
C501217:3-hydroxyphysodic acid; D000890:Anti-Infective Agents; D003990:Dibenzoxepins; D010936:Plant Extracts; C043056:physodic acid