Pd(OH)2/C-mediated selective oxidation of silyl enol ethers by tert-butylhydroperoxide, a useful method for the conversion of ketones to alpha,beta-enones or beta-silyloxy-alpha,beta-enones.
[reaction: see text] Pd(OH)2-catalyzed oxidation of silyl enol ethers by t-BuOOH gives either beta-silyloxy-alpha,beta-enones or alpha,beta-enones in good yields depending on the base used.
Yu
Jin-Quan
JQ
Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, USA.
Wu
Hai-Chen
HC
Corey
E J
EJ