Headspace water-based liquid-phase microextraction.
A new organic-free mode of headspace liquid-phase microextraction termed headspace water-based liquid-phase microextraction has been developed. Five phenols were used as model compounds in the development and evaluation of the procedure. Parameters affecting the extraction efficiency were investigated. Under optimal extraction conditions, very high enrichment factors were achieved. Since only water (with sodium hydroxide to adjust the pH) and a conventional microsyringe were used, this new technique is affordable, efficient, and convenient for extraction of volatile and semivolatile ionizable compounds. In addition, in combination with capillary electrophoresis, the entire analytical process is totally organic solvent-free and is thus environmentally friendly.
Zhang
Jie
J
Department of Chemistry, National University of Singapore, 3 Science Drive 3, Republic of Singapore 117543.
Su
Tao
T
Lee
Hian Kee
HK
D002623:Chemistry Techniques, Analytical / Q000295:instrumentation / Q000379:methods*; D019075:Electrophoresis, Capillary; D006863:Hydrogen-Ion Concentration; D010636:Phenols / Q000032:analysis / Q000302:isolation & purification*; D012972:Sodium Hydroxide / Q000737:chemistry; D013696:Temperature; D014867:Water / Q000032:analysis
D010636:Phenols; D014867:Water; D012972:Sodium Hydroxide