Neuronal polarity: until GSK-3 do us part.
Specification of the axon and dendrites is a critical step in the development of a neuron. Two new studies have shed light on the molecular pathway that controls the establishment of neuronal polarity.
Li
Rong
R
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.
D000818:Animals; D001369:Axons / Q000378:metabolism / Q000502:physiology; D002454:Cell Differentiation / Q000502:physiology*; D016764:Cell Polarity / Q000502:physiology*; D003712:Dendrites / Q000378:metabolism / Q000502:physiology; D038362:Glycogen Synthase Kinase 3 / Q000378:metabolism*; D036341:Intercellular Signaling Peptides and Proteins; D008954:Models, Biological; D009419:Nerve Tissue Proteins / Q000378:metabolism; D009474:Neurons / Q000166:cytology* / Q000502:physiology; D015398:Signal Transduction
D036341:Intercellular Signaling Peptides and Proteins; D009419:Nerve Tissue Proteins; C095114:collapsin response mediator protein-2; D038362:Glycogen Synthase Kinase 3