5-fluorouracil as a phosensitiser.
5-FU exhibits a high fluorescence after irradiation with UV-vis light. An enhancement of the cytostatic activity of 5-FU under UV-vis irradiation was observed on an in vivo experimental model.
Pascu
Mihail Lucian
ML
National Institute for Lasers, Plasma and Radiation Physics, Laser Department, Bucharest - Magurele. mpascu@cost.esf.org
Brezeanu
Mihail
M
Voicu
Letitia
L
Staicu
Angela
A
Carstocea
Benone
B
Pascu
Ruxandra Angela
RA
D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000528:radiation effects* / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D005453:Fluorescence; D005472:Fluorouracil / Q000528:radiation effects* / Q000633:toxicity*; D053685:Laser Therapy; D016727:Orbital Pseudotumor / Q000188:drug therapy / Q000209:etiology; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D011817:Rabbits; D017550:Spectroscopy, Fourier Transform Infrared; D013997:Time Factors; D014466:Ultraviolet Rays
D000964:Antimetabolites, Antineoplastic; D017319:Photosensitizing Agents; D005472:Fluorouracil