Efficient asymmetric synthesis of an azasugar in water.
An extremely efficient asymmetric synthesis of a pyrrolidine azasugar was completed in only four steps in water, without the use of protecting groups and in 60% overall yield from a simple, achiral bis-electrophile.
Lindström
Ulf M
UM
Department of Organic Chemistry, Lund University, P. O. Box 124, SE-221 00, Sweden. ulf.lindstrom@bioorganic.lth.se
Ding
Rui
R
Hidestål
Olle
O