title: [Anesthesia for cesarean section in a parturient taking risperidone and haloperidol].
abstract: We report a case of anesthesia for cesarean section in a schizophrenic patient. Her psychiatric symptoms were well controlled with low doses of risperidone until 35 weeks' gestation, when she suddenly developed psychotic manifestations. Risperidone 6 mg x day(-1) and haloperidol 12 mg x day(-1) PO were given for 3 weeks before delivery. Elective cesarean section was performed under spinal anesthesia at 38 weeks. The parturient showed good psychiatric condition during and after the surgery. The neonate did not show any symptoms which antipsychotics could have caused. Maternal and umbilical blood concentrations of risperidone and haloperidol are reported.
authors.affiliation: Department of Anesthesia, National Hospital Organization Chiba Medical Center, Chiba.
authors.forename: Rie
authors.initials: R
authors.lastname: Kato
authors.forename: Jiro
authors.initials: J
authors.lastname: Sato
authors.forename: Hiroto
authors.initials: H
authors.lastname: Suzuki
mesh_terms: D000328:Adult; D000773:Anesthesia, Obstetrical; D000775:Anesthesia, Spinal; D014150:Antipsychotic Agents / Q000008:administration & dosage* / Q000097:blood; D002585:Cesarean Section; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D006220:Haloperidol / Q000008:administration & dosage* / Q000097:blood; D006801:Humans; D011247:Pregnancy; D018967:Risperidone / Q000008:administration & dosage* / Q000097:blood; D012559:Schizophrenia / Q000188:drug therapy
chemical_list: D014150:Antipsychotic Agents; D006220:Haloperidol; D018967:Risperidone