Vaccines for otitis media: proposals for overcoming obstacles to progress.
Otitis media is a common problem with enormous morbidity worldwide. The development of vaccines to prevent otitis media would have an important human and economic impact. A striking lack of progress in the development, production and clinical testing of vaccines to prevent otitis media has occurred in the past decade. This review outlines a series of specific proposals intended to advance vaccine development for otitis media.
Murphy
Timothy F
TF
Division of Infectious Diseases, Department of Medicine, University at Buffalo, SUNY, USA. murphyt@buffalo.edu
Bakaletz
Lauren O
LO
Kyd
Jennelle M
JM
Watson
Bracie
B
Klein
David L
DL
D001428:Bacterial Vaccines / Q000276:immunology*; D002986:Clinical Trials as Topic; D006801:Humans; D009305:Nasopharynx / Q000382:microbiology; D010033:Otitis Media / Q000517:prevention & control*; D014611:Vaccination; D014765:Viral Vaccines / Q000276:immunology*
D001428:Bacterial Vaccines; D014765:Viral Vaccines