Circular dichroism studies of carbopeptoid-cyclodextrins.
A series of sugar amino acids, based on open chain sugars, have been oligomerised and cyclised. The resulting cyclic carbopeptoids have been examined for desirable properties such as host-guest chemistry (as in cyclodextrins) or self-assembling properties (e.g., peptide nanotubes). Initial studies of these systems, by circular dichroism and X-ray crystallography, have given valuable insight into their stability and properties. One of the four cyclic species studied was found to interact with ion/molecular probes.
Edwards
Alison A
AA
Biological Chemistry, Division of Biomedical Sciences, Imperial College, London, United Kingdom.
Fleet
George W J
GW
Mayes
Ben A
BA
Hunter
Stuart J
SJ
Tranter
George E
GE