title: Thrombogenicity and blood coagulation of a microcatheter prepared from carbon nanotube-nylon-based composite.
abstract: Here we describe the fabrication of nanocomposite-based microcatheter through-melt extrusion utilizing high-purity carbon nanotubes as filler and nylon as matrix. Homogeneous dispersion of carbon nanotubes in nylon can provide novel microcatheters with enhanced mechanical properties (easier to handle) and extremely reduced thrombogenicity or antithrombotic property. The present microcatheter with high performance is highly promising for medical applications.
authors.affiliation: Department of Electrical and Electronic Engineering, Faculty of Engineering, Shinshu University, Nagano, 380-8553, Japan. endo@endomoribu.shinshu-u.ac.jp
authors.forename: Morinobu
authors.initials: M
authors.lastname: Endo
authors.forename: Shozo
authors.initials: S
authors.lastname: Koyama
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Matsuda
authors.forename: Takuya
authors.initials: T
authors.lastname: Hayashi
authors.forename: Yoong-Ahm
authors.initials: YA
authors.lastname: Kim
mesh_terms: D000818:Animals; D001777:Blood Coagulation; D001780:Blood Coagulation Tests; D002404:Catheterization / Q000009:adverse effects*; D004285:Dogs; D008855:Microscopy, Electron, Scanning; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure; D009757:Nylons / Q000737:chemistry*; D013348:Subclavian Artery / Q000473:pathology; D013927:Thrombosis / Q000209:etiology* / Q000473:pathology
chemical_list: D037742:Nanotubes, Carbon; D009757:Nylons