title: Clinical features of ten cases of osteopoikilosis.
abstract: A retrospective study was carried out of the ten cases of osteopoikilosis seen at this Orthopedic Unit over a 15-year period in order to determine the reasons why patients seek consultation, preliminary diagnosis, and associated lesions. Eight patients consulted for problems not related to the locomotor apparatus, and diagnosis was by chance; the other two presented joint pain. The preliminary diagnosis was osteoblastic metastasis in five patients and osteopoikilosis in the other five. None of the patients displayed skin or visceral involvement, but three presented bone alterations. Definitive diagnosis was made by measurement of biochemical markers of bone remodeling, radiography of both hands, and bone scan. Bone biopsy was performed in one case. Although rare, the radiographic symptoms of osteopoikilosis are sufficiently specific to avoid false diagnoses, which may give rise to rigorous and expensive studies for other important disorders.
authors.affiliation: Orthopedics Department, University Hospital Reina Sofia, Córdoba, Spain. pcarpinterob@medynet.com
authors.forename: P
authors.initials: P
authors.lastname: Carpintero
authors.forename: J A
authors.initials: JA
authors.lastname: Abad
authors.forename: P
authors.initials: P
authors.lastname: Serrano
authors.forename: J A
authors.initials: JA
authors.lastname: Serrano
authors.forename: P
authors.initials: P
authors.lastname: Rodríguez
authors.forename: L
authors.initials: L
authors.lastname: Castro
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010023:Osteopoikilosis / Q000000981:diagnostic imaging* / Q000453:epidemiology; D010342:Patient Acceptance of Health Care; D011859:Radiography; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology