[Effects of exopolysaccharide from Tolypocladium sinense on murine immunocytes in vitro].
OBJECTIVE
To elucidate the effects of exopolysaccharide from Tolypocladium sinense on murine immunocytes in vitro.


METHODS
Extracted exopolysccharide (EPS) from cultured Tolypocladium sinense. The effects of EPS on mouse immune parameters were detected in vitro using cell culture techniques.


RESULTS
The results indicated that EPS might significantly not only promote mouse macrophage neutral red uptake ability and cytotoxicity (P < 0.05), but also stimulate their thymus lymphocytes proliferation (P < 0.05).


CONCLUSIONS
EPS may elevate murine cellular immunity to a certain.
Yang
Jinyu
J
Medical School, Nanjing University, Nanjing.
Zhang
Weiyun
W
Shi
Peihua
P
Ling
Lijun
L
Hou
Yayi
Y
Wu
Jianyong
J
D000818:Animals; D049109:Cell Proliferation / Q000187:drug effects; D002478:Cells, Cultured; D002681:China; D008214:Lymphocytes / Q000187:drug effects*; D008262:Macrophage Activation / Q000187:drug effects; D017737:Macrophages, Peritoneal / Q000187:drug effects; D051379:Mice; D010143:Paecilomyces / Q000737:chemistry*; D010587:Phagocytosis / Q000187:drug effects; D011134:Polysaccharides / Q000302:isolation & purification / Q000494:pharmacology*
D011134:Polysaccharides