title: Diagnostic accuracy of mini-mental status examination and revised hasegawa dementia scale for Alzheimer's disease.
abstract: To compare the diagnostic accuracies of the Revised Hasegawa Dementia Scale (HDS-R) and Mini-Mental Status Examination (MMSE) for Alzheimer's diseases (AD), we administered them simultaneously to 82 AD patients and 82 age- and sex-matched nondemented control subjects. The area under the receiver operator curve (AUC) for AD of the HDS-R (AUC(HDS-R)) and MMSE (AUC(MMSE)) were bigger than 0.90 indicating that both tests are useful for detecting AD. However, AUC(HDS-R) (0.952) was significantly larger than that of the AUC(MMSE )(0.902) regardless of the educational level of the subjects, indicating that the HDS-R is more accurate than MMSE in diagnosing AD. Moreover, the superiority of the HDS-R (AUC(HDS-R) = 0.894) to the MMSE (AUC(MMSE) = 0.704) remained significant in mild AD patients alone, who are the focus of screening. In conclusion, the HDS-R is better than the MMSE as a screening instrument for AD.
authors.affiliation: Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea.
authors.forename: K W
authors.initials: KW
authors.lastname: Kim
authors.forename: D Y
authors.initials: DY
authors.lastname: Lee
authors.forename: J H
authors.initials: JH
authors.lastname: Jhoo
authors.forename: J C
authors.initials: JC
authors.lastname: Youn
authors.forename: Y J
authors.initials: YJ
authors.lastname: Suh
authors.forename: Y H
authors.initials: YH
authors.lastname: Jun
authors.forename: E H
authors.initials: EH
authors.lastname: Seo
authors.forename: J I
authors.initials: JI
authors.lastname: Woo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000592:standards*; D008609:Mental Status Schedule / Q000592:standards*; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000592:standards; D012372:ROC Curve; D012720:Severity of Illness Index