title: Tat inhibitors, a new approach: interview with Olaf Kutsch, Ph.D. Interview by John S. James.
abstract: An important potential target for antiretrovirals is the HIV protein Tat (produced by the virus and essential for infection, but is not used by the human body). Years ago, a Tat inhibitor worked well in the laboratory but failed in patients. Modern biotechnology may have shown why--and how to screen for drugs more likely to work.
authors.forename: Olaf
authors.initials: O
authors.lastname: Kutsch
mesh_terms: D019380:Anti-HIV Agents / Q000494:pharmacology*; D004345:Drug Industry; D015696:Gene Products, tat / Q000037:antagonists & inhibitors*
chemical_list: D019380:Anti-HIV Agents; D015696:Gene Products, tat