title: Churg-Strauss syndrome associated with HIV infection.
abstract: A 28-year-old woman with a history of asthma and recent deep venous thrombosis presented with fever, chest pain, and peripheral eosinophilia. The patient was subsequently diagnosed with Churg-Strauss syndrome and HIV infection, representing to our knowledge only the second case of this association. Rheumatologic manifestations of HIV may precede clinical signs of infection. This is significant because steroidal and cytotoxic therapy may potentially worsen HIV infection. As the prevalence of HIV infection rises, there may be atypical presentations of various rheumatologic syndromes. The following case demonstrates a patient whose initial presentation for HIV infection was Churg-Strauss syndrome.
authors.affiliation: University of Maryland School of Medicine, Baltimore, USA. htnguyen@gwu.edu
authors.forename: Hien
authors.initials: H
authors.lastname: Nguyen
authors.forename: Kevin
authors.initials: K
authors.lastname: Ferentz
authors.forename: Alkesh
authors.initials: A
authors.lastname: Patel
authors.forename: Connie
authors.initials: C
authors.lastname: Le
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use; D018791:CD4 Lymphocyte Count; D015267:Churg-Strauss Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006678:HIV / Q000235:genetics / Q000276:immunology; D015483:HIV Antibodies / Q000276:immunology; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D011241:Prednisone / Q000627:therapeutic use; D012367:RNA, Viral / Q000235:genetics
chemical_list: D044966:Anti-Retroviral Agents; D005938:Glucocorticoids; D015483:HIV Antibodies; D012367:RNA, Viral; D011241:Prednisone