title: Neoadjuvant combined chemotherapy followed by external whole pelvic irradiation in two cases of primary extranodal non-Hodgkin's lymphoma of the uterine cervix.
abstract: BACKGROUND
  Primary extranodal lymphomas of the genital tract are rare.
  
  
  METHODS
  As there is no current consensus in its management, we present two further cases and their treatment with neoadjuvant chemotherapy, followed by radiation therapy. A radical hysterectomy with bilateral pelvic lymphadenectomy was performed after primary treatment in one case. Clinical response was complete in both cases and pathological response was documented in one.
  
  
  CONCLUSIONS
  Complete response of these lymphoid neoplasms can be achieved by neoadjuvant chemotherapy followed by external irradiation.
authors.affiliation: Instituto Clinico Oncologico de la Fundacion Arturo Lopez Perez, Santiago de Chile, Chile. herediaf@falp.org
authors.forename: Fernando
authors.initials: F
authors.lastname: Heredia
authors.forename: Marco
authors.initials: M
authors.lastname: Bravo
authors.forename: Mateo
authors.initials: M
authors.lastname: Pierotic
authors.forename: Alejandro
authors.initials: A
authors.lastname: Majlis
authors.forename: Leonardo
authors.initials: L
authors.lastname: Carmona
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy* / Q000532:radiotherapy* / Q000601:surgery; D008727:Methotrexate / Q000008:administration & dosage; D020360:Neoadjuvant Therapy; D011241:Prednisone / Q000008:administration & dosage; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy* / Q000601:surgery; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D002955:Leucovorin; D011241:Prednisone; D008727:Methotrexate