Acute cholecystitis at initial presentation of polyarteritis nodosa.
Polyarteritis nodosa (PAN) is a systemic vasculitis of unknown etiology. Although gastrointestinal involvement may be seen in half of the cases of PAN, vasculitis of the gallbladder at the disease onset is a rare presentation. We report a case of a 48-year-old man who was admitted due to acute cholecystitis. He had complained of myalgia, fever and weight loss for about one month prior to admission. At physical examination, mild hypertension and calf pain were noted. He underwent a cholecystectomy; histopathological evaluation disclosed necrotizing vasculitis suggestive of PAN. We emphasize that cholecystitis may be part of the initial presentation of systemic vasculitis.
Fernandes
Sandra Regina Muchinechi
SR
Disciplina de Reumatologia, Departamento de Clínica Médica, FCM/UNICAMP, State University of Campinas, Sao Paulo, Brazil. SRMFER@uol.com.br
Samara
Adil Muhib
AM
Magalhães
Eduardo Paiva
EP
Sachetto
Zoraida
Z
Metze
Konradin
K
D041881:Cholecystitis, Acute / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D003520:Cyclophosphamide / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005704:Gallbladder / Q000473:pathology* / Q000601:surgery; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010488:Polyarteritis Nodosa / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D016896:Treatment Outcome
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D011241:Prednisone