title: Tumour-like inflammatory abdominal conditions in children.
abstract: The presence of a tumour, poor general condition, features of anaemia, increased erythrocyte sedimentation rates and imaging suggesting malignancy were the common features in 4 different tumour-like abdominal conditions that are extremely rare in childhood. These conditions included: extensive retroperitoneal tumour with rib involvement that turned out to be an inflammatory lesion caused by Actinomyces in a 12-year-old girl; multi-loculated tumour of the mesentery/ovary caused by mesenteric lymphadenopathy in the course of a Salmonella enteritidis infection in a 2.5-year-old girl; tumour of the VII - VIII hepatic segments that turned out to be the focus of granuloma in the course of lambliasis in a 5.5-year-old boy with a history of purulent neck lymphadenopathy and a final suspicion of immunocompromise; and a multi-loculated tumour of the small pelvis and inguinal area that turned out to be an abscess of the iliopsoas muscle in a 16-year-old boy. Apart from the imaging, the lesions required cytological examination of the material harvested by fine-needle biopsies (liver tumour) or histopathological investigations (retroperitoneal tumour, mesenteric/ovarian tumour, liver tumour and--on second surgery--the pelvic tumour) and/or bacteriological examination (all cases), serological examination (liver tumour and mesenteric/ovarian tumour), protozoal investigation (liver tumour), and measurement of AFP levels (mesenteric/ovarian tumour). Surgical treatment (retroperitoneal tumour, mesenteric/ovarian tumour and tumour of the small pelvis) and guided antibiotic therapy (all cases including 15 weeks of antibiotics in the first case) allowed complete recovery in 3 patients (actinomycosis, mesenteric lymphadenopathy, abscess of the iliopsoas muscle). Antibiotic and antiprotozoal therapy cured the granulomatous hepatitis; however this patient tended to develop severe right-sided pleural/pulmonary changes (the child was referred for further diagnosis with suspicion of immunocompromise).
authors.affiliation: Chair and Department of Surgical Paediatrics and Oncology, Pomeranian Medical University, Szczecin, Poland.
authors.forename: I
authors.initials: I
authors.lastname: Latawiec-Mazurkiewicz
authors.forename: P
authors.initials: P
authors.lastname: Juszkiewicz
authors.forename: J
authors.initials: J
authors.lastname: Pacanowski
authors.forename: A
authors.initials: A
authors.lastname: Kwas
authors.forename: M
authors.initials: M
authors.lastname: Rybkiewicz
authors.forename: J
authors.initials: J
authors.lastname: Rudnicki
authors.forename: A
authors.initials: A
authors.lastname: Walecka
authors.forename: S
authors.initials: S
authors.lastname: Musiał
mesh_terms: D000196:Actinomycosis / Q000175:diagnosis*; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007249:Inflammation / Q000209:etiology; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000175:diagnosis*; D008297:Male; D008643:Mesentery; D010051:Ovarian Neoplasms / Q000175:diagnosis; D016659:Psoas Abscess / Q000175:diagnosis*; D012480:Salmonella Infections / Q000150:complications; D012477:Salmonella enteritidis; D014057:Tomography, X-Ray Computed