title: Antibacterial activity and chemical composition of the essential oil of Grammosciadium platycarpum Boiss. from Iran.
abstract: The chemical composition of the essential oils obtained from two samples (GP1 and GP2) of Grammosciadium platycarpum Boiss. was analyzed by GC and GC-MS. The analysis of the oils resulted in the identification of twenty-two constituents. Linalool (79.0%-GP1, 81.8%-GP2) and limonene (10.0%, 5.8%) were found to be the major components, respectively. The in vitro antibacterial activities of these oils and their main compounds against seven Gram-positive and Gram-negative bacteria were investigated. The results exhibited that the total oils and their major components possess strong to moderate activities against all the tested bacteria except for Pseudomonas aeruginosa.
authors.affiliation: Department of Biology, Medicinal Plants Research Institute, Shahid Beheshti University, Evin, P.O. Box 19835-389, Tehran, Iran. a-sonboli@sbu.ac.ir
authors.forename: Ali
authors.initials: A
authors.lastname: Sonboli
authors.forename: Fereshteh
authors.initials: F
authors.lastname: Eftekhar
authors.forename: Morteza
authors.initials: M
authors.lastname: Yousefzadi
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Kanani
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D019661:Apiaceae / Q000737:chemistry*; D001419:Bacteria / Q000187:drug effects; D002849:Chromatography, Gas; D007492:Iran; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D035261:Plant Components, Aerial / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D009822:Oils, Volatile