Synthesis of functionalized nitroarylmagnesium halides via an iodine-magnesium exchange.
[reaction: see text] Various nitro-substituted aryl and heteroaryl iodides undergo an iodine-magnesium exchange reaction when treated with PhMgCl leading to nitro-containing magnesium organometallics. These Grignard reagents display an excellent stability at temperatures below -40 degrees C and do not undergo electron-transfer reactions. They react as expected with various electrophiles.
Sapountzis
Ioannis
I
Department Chemie, Ludwig-Maximilians-University, Butenandtstrasse 5-13, 81377 Munich, Germany.
Dube
Henry
H
Lewis
Robert
R
Gommermann
Nina
N
Knochel
Paul
P