title: Synthesis of C2-chiral bifunctionalised spin labels and their application to troponin C.
abstract: An enantiomeric pair of C2-chiral bifunctionalised spin labels having a pyrrolidine nitroxide moiety, whose configurations were determined by X-ray crystal diffraction analysis, was prepared and applied to troponin C whose binding mode of double disulfide linkage was proved by EPR spectroscopy.
authors.affiliation: Graduate School of Human & Environmental Studies, Kyoto University, Sakyo-ku, Yoshida, Kyoto 606-8501, Japan.
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Chatani
authors.forename: Motoyoshi
authors.initials: M
authors.lastname: Nakamura
authors.forename: Hidenobu
authors.initials: H
authors.lastname: Akahane
authors.forename: Naoki
authors.initials: N
authors.lastname: Kohyama
authors.forename: Masayasu
authors.initials: M
authors.lastname: Taki
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Arata
authors.forename: Yukio
authors.initials: Y
authors.lastname: Yamamoto
mesh_terms: D000818:Animals; D002244:Carbon / Q000737:chemistry*; D002645:Chickens; D004578:Electron Spin Resonance Spectroscopy; D008958:Models, Molecular; D017434:Protein Structure, Tertiary; D013113:Spin Labels; D013237:Stereoisomerism; D019209:Troponin C / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D013113:Spin Labels; D019209:Troponin C; D002244:Carbon