title: Potent and selective inhibition of class II alpha-D-mannosidase activity by a bicyclic sulfonium salt.
authors.affiliation: Université de Picardie Jules Verne, Faculté des Sciences, Laboratoire des Glucides, FRE 2779, 33, rue Saint Leu, 80039 Amiens, France. siriward@ccrc.uga.edu
authors.forename: Aloysius
authors.initials: A
authors.lastname: Siriwardena
authors.forename: Heather
authors.initials: H
authors.lastname: Strachan
authors.forename: Samer
authors.initials: S
authors.lastname: El-Daher
authors.forename: Gemma
authors.initials: G
authors.lastname: Way
authors.forename: Bryan
authors.initials: B
authors.lastname: Winchester
authors.forename: John
authors.initials: J
authors.lastname: Glushka
authors.forename: Kelley
authors.initials: K
authors.lastname: Moremen
authors.forename: Geert-Jan
authors.initials: GJ
authors.lastname: Boons
mesh_terms: D003500:Cyclization; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D020128:Inhibitory Concentration 50; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D008247:Lysosomes / Q000187:drug effects / Q000201:enzymology; D015394:Molecular Structure; D013452:Sulfonium Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D043323:alpha-Mannosidase / Q000037:antagonists & inhibitors* / Q000145:classification / Q000378:metabolism*
chemical_list: D004791:Enzyme Inhibitors; D013452:Sulfonium Compounds; D043323:alpha-Mannosidase