title: Bio-hazards and drug reactions: a cautionary tale.
abstract: Laboratory acquired infection with toxoplasmosis has been described. The clinical features in this situation can vary from asymptomatic to severe disease. Prophylactic therapy is recommended on the basis of clinical experience and case reports. We describe a case in a young man, where prophylaxis resulted in neutropenia complicated by subsequent Listeria meningitis.
authors.affiliation: The Infection, Tropical Medicine and Counselling Service, The Brownlee Centre, Gartnavel General Hospital, Glasgow, UK.
authors.forename: Erica
authors.initials: E
authors.lastname: Peters
authors.forename: Andrew
authors.initials: A
authors.lastname: Seaton
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004338:Drug Combinations; D006801:Humans; D002955:Leucovorin / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D008584:Meningitis, Listeria / Q000175:diagnosis / Q000209:etiology; D009503:Neutropenia / Q000139:chemically induced / Q000150:complications; D016273:Occupational Exposure; D011739:Pyrimethamine / Q000009:adverse effects* / Q000627:therapeutic use; D013411:Sulfadiazine / Q000009:adverse effects* / Q000627:therapeutic use; D014123:Toxoplasmosis / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D013411:Sulfadiazine; D002955:Leucovorin; D011739:Pyrimethamine