title: [Effects of jiantai liquid on the expression of estrogen/progesterone receptors in embryo implantation dysfunction mice endometrium].
abstract: OBJECTIVE
  To explore the mechanism of Jiantai liquid on the endometrium development of embryo implantation dysfunction mice.
  
  
  METHODS
  The model of embryo implantation dysfunction mice was induced by mifepristone and treated by Jiantai liquid. All animals were sacrificed on day 8 of pregnancy. Estradiol and progesterone concentrations in serum and endometrium tissue homogenates were measured by radioimmunoassay method, the endometial expressions of estrogen receptor (ER)and progesterone receptor (PR)assessed by immunohistochemical SP method.
  
  
  RESULTS
  There were no significantly differences in the estradiol and progesterone concentrations in serum and uterus tissue homogenates among three groups( P > 0.05). Absorbency and area rate of ER, PR in model group' s gland and stroma were higher than those in model group(P < 0.05), which was similar with the control group( P > 0.05).
  
  
  CONCLUSIONS
  Jiantai liquid increase the implantation rate and improve the endometrial development by increasing the expressions of ER, PR in endometrium of embryo implantation dysfunction
authors.affiliation: Deparment of Integrated Traditional Chinese & Western Medicine, Tongji Hospital, Wuhan 430030, China. tjyjliu@hotmail.com
authors.forename: Yan-juan
authors.initials: YJ
authors.lastname: Liu
authors.forename: Guang-ying
authors.initials: GY
authors.lastname: Huang
authors.forename: Ming-wei
authors.initials: MW
authors.lastname: Yang
authors.forename: Fu-er
authors.initials: FE
authors.lastname: Lu
authors.forename: Ping
authors.initials: P
authors.lastname: Gong
mesh_terms: D000818:Animals; D027885:Astragalus propinquus / Q000737:chemistry; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D010065:Embryo Implantation, Delayed / Q000187:drug effects*; D004717:Endometrium / Q000378:metabolism*; D005260:Female; D028183:Loranthaceae / Q000737:chemistry; D008297:Male; D051379:Mice; D015735:Mifepristone / Q000037:antagonists & inhibitors / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry; D011960:Receptors, Estrogen / Q000378:metabolism*; D011980:Receptors, Progesterone / Q000378:metabolism*; D027561:Salvia miltiorrhiza / Q000737:chemistry
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D015735:Mifepristone