title: Optimal cytoreduction after combined resection and radiofrequency ablation of hepatic metastases from recurrent malignant ovarian tumors.
abstract: BACKGROUND
  The role of radiofrequency ablation (RFA) in the treatment of hepatic metastases from recurrent ovarian tumors is undefined.
  
  
  METHODS
  Three patients with hepatic lesions from recurrent ovarian cancers underwent a combined partial hepatectomy with radiofrequency ablation (RFA) to achieve optimal tumor cytoreduction. Follow-up radiological studies as well as serial tumor markers are consistent with disease-free survival after 39, 13, and 9 months.
  
  
  CONCLUSIONS
  These results demonstrate the feasibility and safety of RFA for metastatic ovarian lesions to the liver in patients previously deemed as poor or non-surgical candidates, and suggest the potential for improvement in survival over unresected patients or in patients resected with residual disease.
authors.affiliation: Department of Surgery, Keck-USC School of Medicine, 1510 San Pablo Street, HCC 430, Los Angeles, CA 90033, USA. rmateo@surgery.usc.edu
authors.forename: Rod
authors.initials: R
authors.lastname: Mateo
authors.forename: Gagandeep
authors.initials: G
authors.lastname: Singh
authors.forename: Nicolas
authors.initials: N
authors.lastname: Jabbour
authors.forename: Suzanne
authors.initials: S
authors.lastname: Palmer
authors.forename: Yuri
authors.initials: Y
authors.lastname: Genyk
authors.forename: Lynda
authors.initials: L
authors.lastname: Roman
mesh_terms: D000368:Aged; D017115:Catheter Ablation; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery*