title: Ampulla cardiomyopathy after hypoglycemia in three young female patients with anorexia nervosa.
abstract: Ampulla cardiomyopathy is named after the echocardiographic abnormalities occurring in this condition, characterized by extensive akinesis (ballooning ) of the apical region with hypercontraction of the basal segment of the ventricle. We describe 3 young female anorexia nervosa patients showing evidence of this cardiac complication after hypoglycemia. One case was complicated by echocardiographically confirmed ampulla cardiomyopathy while the other 2 patients showed increases in myocardial enzymes and transient electrocardiographic abnormalities consistent with this complication. The precipitating event for all three patients was hypoglycemic coma, and this is the first case report in which this factor lead to the complication of ampulla cardiomyopathy in anorexia nervosa patients.
authors.affiliation: Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, School of Medicine, Shinjuku-ku, Tokyo 162-8666.
authors.forename: Rina
authors.initials: R
authors.lastname: Ohwada
authors.forename: Mari
authors.initials: M
authors.lastname: Hotta
authors.forename: Hironari
authors.initials: H
authors.lastname: Kimura
authors.forename: Sachiko
authors.initials: S
authors.lastname: Takagi
authors.forename: Naoki
authors.initials: N
authors.lastname: Matsuda
authors.forename: Kaoru
authors.initials: K
authors.lastname: Nomura
authors.forename: Kazue
authors.initials: K
authors.lastname: Takano
mesh_terms: D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D001786:Blood Glucose / Q000378:metabolism; D009202:Cardiomyopathies / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D005947:Glucose / Q000008:administration & dosage / Q000627:therapeutic use; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D007003:Hypoglycemia / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D007262:Infusions, Intravenous; D009200:Myocardial Contraction / Q000502:physiology; D011877:Radionuclide Imaging; D013549:Sweetening Agents / Q000008:administration & dosage / Q000627:therapeutic use; D014166:Transferases / Q000097:blood; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology
chemical_list: D001786:Blood Glucose; D013549:Sweetening Agents; D014166:Transferases; D005947:Glucose