The relation between visual hallucinations and visual evoked potential in Parkinson disease.
OBJECTIVE
The pathophysiology of hallucinations in Parkinson disease is poorly understood. This study investigated the relation between visual hallucination and visual evoked potentials (VEPs) in Parkinson disease.


METHODS
Nineteen patients with Parkinson disease were studied. The authors divided patients into 2 groups: patients with visual hallucinations (VH group) and those without visual hallucinations (no-VH group). VEPs using a checkerboard stimulus were recorded under a drug-free state.


RESULTS
On multivariate regression analysis, only the average P100 latency was selected and remained significant after the backward elimination method.


CONCLUSIONS
The authors demonstrated a close association between visual hallucinations and elongated VEP latency in Parkinson disease. VEPs may become one of the predictors for visual hallucination.
Matsui
Hideaki
H
Department of Neurology, Sumitomo Hospital, Osaka, Japan. matsui-hideaki@sumitomo-hp.or.jp
Udaka
Fukashi
F
Tamura
Akiko
A
Oda
Masaya
M
Kubori
Tamotsu
T
Nishinaka
Kazuto
K
Kameyama
Masakuni
M
D000368:Aged; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005260:Female; D006212:Hallucinations / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000503:physiopathology*; D010775:Photic Stimulation; D011930:Reaction Time / Q000502:physiology / Q000528:radiation effects