[Autoimmune changes in patients with multiple gastroduodenal ulcers and their pathogenetic significance in the complex surgical treatment].
There were examined 73 patients, suffering for multiple gastroduodenal ulcers and included in the main group, and 56 patients with solitary gastroduodenal ulcer, included in the comparison group. The lymphocytes migration impeding reaction (LMIR) was applied to characterize the autoimmune changes in both groups of patients. It was established, that in the patients with multiple gastroduodenal ulcers and with ulcers of small sizes the LMIR was essentially lowered in relation to all the autoantigenes investigated. The data obtained trust the important significance of the immunological investigation conduction in substantiation of the pathologic process pathogenesis, what must be taken into account during performance of surgical treatment and while applying the treatment-rehabilitation measures after the operation.
Ioffe
I V
IV
D000328:Adult; D001324:Autoantigens / Q000032:analysis; D015551:Autoimmunity / Q000276:immunology*; D002634:Chemotaxis, Leukocyte / Q000276:immunology*; D013505:Digestive System Surgical Procedures / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000276:immunology / Q000601:surgery*; D013601:T-Lymphocytes / Q000276:immunology*
D001324:Autoantigens