[Effect of tobacco smoke exposure on urine lead concentration of pregnant women].
Among other toxic compounds, tobacco smoke contains also heavy metals, for example lead. Lead can cross the placenta barrier and have negative influences on fetus development. In the study compared urine lead concentration of pregnancy women exposed to tobacco smoke (active smokers and exposed to environmental tobacco smoke--ETS) with unexposed. There was find that mean urine lead concentrations in groups of pregnant women exposed and unexposed to tobacco smoke was no different (F2,189=0.2 p>0.8). However it was found that in urine of women exposed to tobacco smoke the concentration of lead increase with increase the concentration of cotinine (r2=0.14, t106=4.2, p<<0.0001).
Gomółka
Ewa
E
Zakład Toksykologii Klinicznej i Przemysłowej Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie. labtoxuj@cm-uj.krakow.pl
Morawska
Agnieszka
A
Jenner
Bartosz
B
Piekoszewski
Wojciech
W
Breborowicz
Grzegorz H
GH
D016022:Case-Control Studies; D003367:Cotinine / Q000652:urine*; D005260:Female; D047109:Fetal Development; D006801:Humans; D007854:Lead / Q000652:urine*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000652:urine*; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects*; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*
D014028:Tobacco Smoke Pollution; D007854:Lead; D003367:Cotinine