Transient band-like keratopathy after treatment for seborrheic dermatitis.
OBJECTIVE
To describe a case of transient band-like keratopathy after ocular exposure to fluocinonide cream and ketoconazole shampoo.


METHODS
Observational case report.


RESULTS
A 40-year-old patient presented with acute pain, photophobia, lacrimation, and redness in 1 eye. The symptoms began while using fluocinonide cream and ketoconazole shampoo as treatment of seborrheic dermatitis of the scalp. Examination revealed white clumpy deposits in a horizontal band across the inferocentral corneal epithelium and conjunctival hyperemia. Corneal scrapings revealed no cells or organisms, and culture was negative. The lipophilic deposits dissolved during slide fixation and processing. With conservative treatment the deposits resolved in 3 days.


CONCLUSIONS
We present a case of transient band-like corneal deposit, a novel complication of fluocinonide and ketoconazole exposure.
Savage
Howard I
HI
Department of Ophthalmology, George Washington University Medical Center, Washington, DC 20037, USA. hsavage@mfa.gwu.edu
Edgington
Bryan
B
Appel
Jason
J
D000287:Administration, Topical; D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage / Q000009:adverse effects*; D003316:Corneal Diseases / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D012628:Dermatitis, Seborrheic / Q000188:drug therapy*; D019573:Epithelium, Corneal / Q000187:drug effects / Q000473:pathology; D004917:Erythromycin / Q000008:administration & dosage; D005260:Female; D005447:Fluocinonide / Q000008:administration & dosage / Q000009:adverse effects*; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007654:Ketoconazole / Q000008:administration & dosage / Q000009:adverse effects*; D009824:Ointments
D000935:Antifungal Agents; D005938:Glucocorticoids; D009824:Ointments; D005447:Fluocinonide; D004917:Erythromycin; D007654:Ketoconazole