title: A hystopathological study of thyroarytenoid muscle invasion in early (T1) glottic carcinoma.
abstract: METHODS
  Surgical specimens belonging to 16 patients who underwent partial laryngectomy for T1 glottic cancer were subjected to detailed histopathologic examination; 11 of the patients were staged as T1a while 5 were staged as T1b.
  
  
  RESULTS
  It was detected that in 11 patients the tumor was confined to the mucosal or submucosal connective layer, and in 5 (31.2%) cases, the tumor invaded the thyroarytenoid (TA) muscle. In cases involving the one-third anterior part of the vocal cords and the anterior commissure, a 50% (4/8) TA muscle invasion was detected.
  
  
  CONCLUSIONS
  Our finding TA muscle invasion at the rate of 31.2% in our 16 case series clinically staged as T1 revealed that deep invasion did not always impair the vocal cord mobility. Observing TA muscle invasion at the rate of 50% in cases involving the one-third anterior part of the vocal cord and the anterior commissure suggested that TA muscle invasion in the anterior part did not significantly impair mobility.
authors.affiliation: Department of II Otorhinolaryngology-Head and Neck Surgery, Social Security Organization, Ankara Education Hospital, Sivas, Turkey. sinankocaturk@yahoo.com
authors.forename: Sinan
authors.initials: S
authors.lastname: Kocatürk
authors.forename: Unsal
authors.initials: U
authors.lastname: Han
authors.forename: D
authors.initials: D
authors.lastname: Yilmazer
authors.forename: Binnur
authors.initials: B
authors.lastname: Onal
authors.forename: Unsal
authors.initials: U
authors.lastname: Erkam
mesh_terms: D002281:Carcinoma, Basosquamous / Q000473:pathology* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D005931:Glottis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007124:Immunoenzyme Techniques; D007821:Laryngeal Muscles / Q000473:pathology*; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D007825:Laryngectomy; D007828:Laryngoscopy; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011379:Prognosis; D014826:Vocal Cord Paralysis / Q000473:pathology / Q000601:surgery; D014827:Vocal Cords / Q000473:pathology / Q000601:surgery