title: Spontaneous intracerebral hemorrhage in young adults.
abstract: Few studies have addressed intracerebral hemorrhage (ICH) in younger adults. We studied spontaneous ICH in adults <or=45 years of age. We retrospectively reviewed patients hospitalized with ICH between 2000 and 2001 to investigate incidence, etiology, risk factors, bleeding sites, management, and prognosis. Patients (224 men, 72 women; 37.0 +/- 7.7 years) had a mortality rate of 24%. The most common risk factor for mortality was hypertension (HTN) (48.7%). Bleeding was most common in the ganglion (49.0%). Multiple hemorrhages (83.3%) caused the highest mortality, with the most common cause of mortality being HTN (46.6%). Coagulopathy (62.5%) caused the highest mortality based on etiologic classification. Recurrent HTN-induced hemorrhage rate was 3.6%. In Taiwanese adults <or=45 years of age, ICHs mainly involve the ganglion and result from HTN. Rates of HTN-induced hemorrhage are higher in Taiwan (46.6%) than elsewhere. Differences between races or countries should be investigated further.
authors.affiliation: Department of Neurology, Chang Gung Memorial Hospital, Chiayi, Taiwan.
authors.forename: S-L
authors.initials: SL
authors.lastname: Lai
authors.forename: S-T
authors.initials: ST
authors.lastname: Chen
authors.forename: T-H
authors.initials: TH
authors.lastname: Lee
authors.forename: L-S
authors.initials: LS
authors.lastname: Ro
authors.forename: S-P
authors.initials: SP
authors.lastname: Hsu
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D002543:Cerebral Hemorrhage / Q000453:epidemiology* / Q000401:mortality / Q000503:physiopathology*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D009026:Mortality; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D013624:Taiwan / Q000453:epidemiology