title: Circular dichroism studies of carbopeptoid-cyclodextrins.
abstract: A series of sugar amino acids, based on open chain sugars, have been oligomerised and cyclised. The resulting cyclic carbopeptoids have been examined for desirable properties such as host-guest chemistry (as in cyclodextrins) or self-assembling properties (e.g., peptide nanotubes). Initial studies of these systems, by circular dichroism and X-ray crystallography, have given valuable insight into their stability and properties. One of the four cyclic species studied was found to interact with ion/molecular probes.
authors.affiliation: Biological Chemistry, Division of Biomedical Sciences, Imperial College, London, United Kingdom.
authors.forename: Alison A
authors.initials: AA
authors.lastname: Edwards
authors.forename: George W J
authors.initials: GW
authors.lastname: Fleet
authors.forename: Ben A
authors.initials: BA
authors.lastname: Mayes
authors.forename: Stuart J
authors.initials: SJ
authors.lastname: Hunter
authors.forename: George E
authors.initials: GE
authors.lastname: Tranter