Body temperature - a marker of infarct size in the era of early reperfusion.
We measured body temperature in 40 consecutive patients treated for a first ST elevation acute myocardial infarction (AMI) with primary percutaneous coronary interventions. Left ventricular function was assessed by echocardiography, and blood samples were drawn for highly sensitive C-reactive protein (hs-CRP), white blood cell (WBC) count, fibrinogen, creatine kinase (CK), and cardiac troponin I levels (cTnI). The median (25th, 75th quartiles) peak 24-hour temperature was 37.4 degrees C (36.9 degrees C, 37.6 degrees C). Variables significantly associated with peak 24-hour temperature were CK (p = 0.01, r = 0.42), wall motion index (p = 0.01, r = 0.41), hs-CRP (p = 0.01, r = 0.41), and cTnI (p = 0.03, r = 0.35). There was no significant correlation between peak 24-hour temperature and WBC count (p = 0.39, r = 0.14) and fibrinogen (p = 0.12, r = 0.21). Thus, peak 24-hour body temperature after ST elevation AMI probably reflects infarct size rather than a nonspecific inflammatory response.
Ben-Dor
Itsik
I
Rabin Medical Center, Petah-Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Israel.
Haim
Moti
M
Rechavia
Eldad
E
Murininkas
Daniel
D
Nahon
Merav
M
Harell
Daniella
D
Porter
Avital
A
Iakobishvili
Zaza
Z
Scapa
Erez
E
Battler
Alexander
A
Hasdai
David
D
D015415:Biomarkers / Q000097:blood; D001831:Body Temperature / Q000502:physiology*; D002097:C-Reactive Protein / Q000032:analysis; D015331:Cohort Studies; D003402:Creatine Kinase / Q000097:blood; D004452:Echocardiography; D005260:Female; D005334:Fever / Q000503:physiopathology*; D005340:Fibrinogen / Q000032:analysis; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology; D009203:Myocardial Infarction / Q000097:blood / Q000473:pathology* / Q000503:physiopathology; D015425:Myocardial Reperfusion; D011446:Prospective Studies; D019210:Troponin I / Q000097:blood; D016277:Ventricular Function, Left / Q000502:physiology
D015415:Biomarkers; D019210:Troponin I; D005340:Fibrinogen; D002097:C-Reactive Protein; D003402:Creatine Kinase