title: Sensititre YeastOne caspofungin susceptibility testing of Candida clinical isolates: correlation with results of NCCLS M27-A2 multicenter study.
abstract: The ability of Sensititre YeastOne to discriminate isolates with reduced caspofungin susceptibility was determined against 36 Candida spp. (6 with a known FKS1 mutation). Results were compared with those of M27-A2. The MIC endpoint was 100% growth inhibition. Overall agreement (+/-2 log2) was 87.16%. Sensititre YeastOne detected strains with reduced caspofungin susceptibility.
authors.affiliation: Unidad de Microbiología Experimental-Centro de Investigación, Hospital Universitario La Fe, Avenida Campanar 21, 46009 Valencia, Spain. canton_emi@gva.es
authors.forename: Emilia
authors.initials: E
authors.lastname: Cantón
authors.forename: Javier
authors.initials: J
authors.lastname: Pemán
authors.forename: Miguel
authors.initials: M
authors.lastname: Gobernado
authors.forename: Elena
authors.initials: E
authors.lastname: Alvarez
authors.forename: Fernando
authors.initials: F
authors.lastname: Baquero
authors.forename: Ramón
authors.initials: R
authors.lastname: Cisterna
authors.forename: Joaquina
authors.initials: J
authors.lastname: Gil
authors.forename: Estrella
authors.initials: E
authors.lastname: Martín-Mazuelos
authors.forename: Carmen
authors.initials: C
authors.lastname: Rubio
authors.forename: Aurora
authors.initials: A
authors.lastname: Sánchez-Sousa
authors.forename: Carmen
authors.initials: C
authors.lastname: Serrano
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000145:classification / Q000187:drug effects*; D002177:Candidiasis / Q000382:microbiology; D000077336:Caspofungin; D025141:Drug Resistance, Fungal; D054714:Echinocandins; D006801:Humans; D055666:Lipopeptides; D008826:Microbial Sensitivity Tests / Q000379:methods; D010456:Peptides, Cyclic / Q000494:pharmacology*; D011933:Reagent Kits, Diagnostic
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D010456:Peptides, Cyclic; D011933:Reagent Kits, Diagnostic; D000077336:Caspofungin