title: Changes in electric charge and phospholipids composition in erythrocyte membrane of ethanol--poisoned rats after administration of teas.
abstract: Erythrocyte membrane components and electric charge can be modified by ethanol and by compounds formed as a result of its metabolism, particularly be reactive oxygen species (ROS). The effects of ROS can be neutralized by administering preparations with antioxidant properties. The natural preparations of this kind are teas. For this reason, it has been the purpose of this work to determine effect of green and black tea on membrane electric charge and phospholipids composition of an erythrocyte membrane from rats intoxicated with ethanol. Electrophoresis technique and HPLC have been applied to the above-mentioned studies. Ethanol administration caused an increase in erythrocyte surface charge density and phospholipids composition in the membrane. Administration of green and black tea with ethanol to the rats partially neutralizes the changes provoked by ethanol, and the action of green tea was stronger than that of black tea.
authors.affiliation: Institute of Chemistry, University in Białystok, Białystok.
authors.forename: Izabela
authors.initials: I
authors.lastname: Dobrzyńska
authors.forename: Barbara
authors.initials: B
authors.lastname: Szachowicz-Petelska
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Skrzydlewska
authors.forename: Zbigniew Artur
authors.initials: ZA
authors.lastname: Figaszewski
mesh_terms: D000818:Animals; D002492:Central Nervous System Depressants / Q000506:poisoning*; D004910:Erythrocyte Membrane / Q000378:metabolism*; D000431:Ethanol / Q000506:poisoning*; D008297:Male; D010743:Phospholipids / Q000097:blood*; D051381:Rats; D017208:Rats, Wistar; D013662:Tea
chemical_list: D002492:Central Nervous System Depressants; D010743:Phospholipids; D013662:Tea; D000431:Ethanol