title: [Timing and choice of intervention in necrotising pancreatitis].
abstract: Three patients, men aged 49, 62 and 33 years, were admitted with acute abdominal symptoms due to necrotising pancreatitis. They underwent multiple interventions during a hospital stay of several months, but ultimately recovered completely. In case of infected (peri-)pancreatic necrosis, intervention is required. Good clinical judgement in the differentiation between the septic inflammatory-response syndrome, sepsis and infected necrosis as the cause of the clinical condition is important. Because of the different intervention strategies, treatment by a team comprising a radiologist, gastroenterologist, intensive care specialist and gastrointestinal surgeon is required. Randomised studies on intervention in infected pancreatic necrosis are lacking. In 2002, to improve the treatment of patients with acute (necrotising) pancreatitis via a combination of research, consultation and centralisation, the Dutch Acute Pancreatitis Study Group was formed.
authors.affiliation: Afd. Heelkunde, Universitair Medisch Centrum Utrecht, Huispost G04.228, Postbus 85.500, 3508 GA Utrecht.
authors.forename: M G H
authors.initials: MG
authors.lastname: Besselink
authors.forename: T L
authors.initials: TL
authors.lastname: Bollen
authors.forename: M A
authors.initials: MA
authors.lastname: Boermeester
authors.forename: B
authors.initials: B
authors.lastname: van Ramshorst
authors.forename: M S
authors.initials: MS
authors.lastname: van Leeuwen
authors.forename: H G
authors.initials: HG
authors.lastname: Gooszen
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D019283:Pancreatitis, Acute Necrotizing / Q000601:surgery / Q000628:therapy*; D010346:Patient Care Management; D010348:Patient Care Team; D017410:Practice Guidelines as Topic; D012955:Societies, Medical / Q000458:organization & administration* / Q000592:standards; D016896:Treatment Outcome