title: A simple glycol nucleic acid.
abstract: A glycol nucleic acid (GNA) with an acyclic propylene glycol phosphodiester backbone forms stable antiparallel duplexes following the Watson-Crick base pairing rules.
authors.affiliation: Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104, USA.
authors.forename: Lilu
authors.initials: L
authors.lastname: Zhang
authors.forename: Adam
authors.initials: A
authors.lastname: Peritz
authors.forename: Eric
authors.initials: E
authors.lastname: Meggers
mesh_terms: D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry; D004852:Epoxy Compounds / Q000737:chemistry; D006018:Glycols / Q000737:chemistry*; D009696:Nucleic Acids / Q000737:chemistry*; D009711:Nucleotides / Q000737:chemistry; D009841:Oligonucleotides / Q000138:chemical synthesis / Q000737:chemistry; D020005:Propanols / Q000737:chemistry; D012313:RNA / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D004852:Epoxy Compounds; D006018:Glycols; D009696:Nucleic Acids; D009711:Nucleotides; D009841:Oligonucleotides; D020005:Propanols; D012313:RNA; D004247:DNA; C004312:glycidol