title: Treatment of stress fractures in athletes with intravenous pamidronate.
abstract: OBJECTIVE
  To determine if the use of a second-generation biphosphonate, pamidronate, is an effective treatment option for stress fractures in intercollegiate athletes. Pamidronate is successfully used to increase bone mass in patients with Charcot arthropathy and osteoporosis.
  
  
  METHODS
  Case series.
  
  
  METHODS
  Academic sports medicine clinic with primary responsibility for intercollegiate athletics.
  
  
  METHODS
  Five intercollegiate female athletes.
  
  
  METHODS
  Intravenous pamidronate administered weekly for a total of 5 treatments.
  
  
  METHODS
  Athletes' ability to continue training without restrictions.
  
  
  RESULTS
  Four of 5 treated athletes were able to continue training and competition within 1 week of treatment.
  
  
  CONCLUSIONS
  Pamidronate may be a useful adjunct to the treatment of stress fractures.
authors.affiliation: Department of Orthopaedics, SL-32, Tulane Institute of Sports Medicine, Tulane University Health Science Center, New Orleans, LA 70112, USA. gstewart@tulane.edu
authors.forename: Gregory W
authors.initials: GW
authors.lastname: Stewart
authors.forename: Michael E
authors.initials: ME
authors.lastname: Brunet
authors.forename: Melvin R
authors.initials: MR
authors.lastname: Manning
authors.forename: Frederick A
authors.initials: FA
authors.lastname: Davis
mesh_terms: D000293:Adolescent; D000328:Adult; D001265:Athletic Injuries / Q000188:drug therapy*; D004164:Diphosphonates / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D015775:Fractures, Stress / Q000188:drug therapy*; D006801:Humans; D009325:Nausea / Q000139:chemically induced; D000077268:Pamidronate; D016896:Treatment Outcome
chemical_list: D004164:Diphosphonates; D000077268:Pamidronate