title: Direct conversion of N-methoxy-N-methylamides (Weinreb amides) to ketones via a nonclassical Wittig reaction.
abstract: [reaction: see text] N-Methoxy-N-methylamides (Weinreb amides) are converted efficiently into ketones by reaction with alkylidenetriphenylphosphoranes and in situ hydrolysis of the product.
authors.affiliation: Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow G1 1XL, UK. john.murphy@strath.ac.uk
authors.forename: John A
authors.initials: JA
authors.lastname: Murphy
authors.forename: Aurélien G J
authors.initials: AG
authors.lastname: Commeureuc
authors.forename: Thomas N
authors.initials: TN
authors.lastname: Snaddon
authors.forename: Thomas M
authors.initials: TM
authors.lastname: McGuire
authors.forename: Tanweer A
authors.initials: TA
authors.lastname: Khan
authors.forename: Kevin
authors.initials: K
authors.lastname: Hisler
authors.forename: Mark L
authors.initials: ML
authors.lastname: Dewis
authors.forename: Robert
authors.initials: R
authors.lastname: Carling