title: Mycobacterium keratitis after laser in situ keratomileusis.
abstract: OBJECTIVE
  We present a case of Mycobacterium keratitis after laser in situ keratomileusis (LASIK).
  
  
  METHODS
  A retrospective case report.
  
  
  RESULTS
  A 40-year-old woman developed Mycobacterium chelonae keratitis in the right eye 2 weeks after bilateral LASIK. The diagnosis was made by acid-fast staining of corneal scrapings on admission and confirmed by culture results 2 weeks later. Intensive treatment with topical amikacin (25 mg/mL) and ciprofloxacin and partial excision of the flap led to resolution of the infection after 2 months of therapy. In addition, topical methylprednisolone (1 mg/mL) was necessary to control inflammation and pain. No recurrence was found during the 1-year follow-up period. The final uncorrected and corrected visual acuity in the right eye was 20/25 and 20/20, respectively.
  
  
  CONCLUSIONS
  Mycobacterium keratitis is a potentially vision-threatening complication after LASIK. Early recognition of the organisms and aggressive treatment if infection develops may improve the outcome. When surgery is indicated, partial flap amputation, which may help to resolve the infection and preserve better vision, may be considered.
authors.affiliation: Department of Ophthalmology, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.
authors.forename: Kai-Shiang
authors.initials: KS
authors.lastname: Yang
authors.forename: Yeong-Fong
authors.initials: YF
authors.lastname: Chen
authors.forename: Ken-Kuo
authors.initials: KK
authors.lastname: Lin
authors.forename: Ching-Hsi
authors.initials: CH
authors.lastname: Hsiao
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000583:Amikacin / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002939:Ciprofloxacin / Q000008:administration & dosage; D003315:Cornea / Q000382:microbiology* / Q000473:pathology; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007634:Keratitis / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D009165:Mycobacterium Infections, Nontuberculous / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D016926:Mycobacterium chelonae / Q000302:isolation & purification*; D012086:Reoperation; D012189:Retrospective Studies; D013530:Surgical Wound Infection / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D000583:Amikacin