title: Molecular diversity of Artocarpus champeden (Moraceae): a species endemic to Indonesia.
abstract: A summary of results obtained in the study of natural products isolated from a Moraceae species Artocarpus champeden is presented. The various classes of 3-prenylflavonoids isolated and the biogenetical correlation between the metabolites are discussed. Some of the flavonoids exhibited strong cytotoxicity against murine leukemia P388 cell lines, suggesting that flavonoids derived from moraceous plants represent a plausible unexplored resource of novel antitumor leads.
authors.affiliation: Natural Products Research Group, Department of Chemistry, Institut Teknologi Bandung, Jalan Ganeca 10, Bandung 40132, Indonesia.
authors.forename: Euis H
authors.initials: EH
authors.lastname: Hakim
authors.forename: Lia D
authors.initials: LD
authors.lastname: Juliawaty
authors.forename: Yana M
authors.initials: YM
authors.lastname: Syah
authors.forename: Sjamsul A
authors.initials: SA
authors.lastname: Achmad
mesh_terms: D000818:Animals; D031622:Artocarpus / Q000737:chemistry / Q000145:classification* / Q000235:genetics*; D001685:Biological Factors / Q000302:isolation & purification / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D045744:Cell Line, Tumor; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007214:Indonesia; D007941:Leukemia P388; D051379:Mice; D008517:Phytotherapy
chemical_list: D001685:Biological Factors; D005419:Flavonoids