Quinazolines revisited: search for novel anxiolytic and GABAergic agents.
A systematic approach through computer assisted design to identify novel quinazolines having anxiolytic and GABAergic activity has been reported.
Goel
R K
RK
Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar 143 005, India. goelrk_us@yahoo.com <goelrk_us@yahoo.com>
Kumar
Vipan
V
Mahajan
M P
MP
D000818:Animals; D014151:Anti-Anxiety Agents / Q000737:chemistry* / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D018682:GABA Agents / Q000737:chemistry* / Q000494:pharmacology; D018755:GABA Agonists / Q000737:chemistry / Q000494:pharmacology; D058785:GABA-A Receptor Agonists; D018782:Maze Learning / Q000187:drug effects / Q000502:physiology; D051379:Mice; D011799:Quinazolines / Q000737:chemistry* / Q000494:pharmacology; D011963:Receptors, GABA-A / Q000502:physiology
D014151:Anti-Anxiety Agents; D018682:GABA Agents; D018755:GABA Agonists; D058785:GABA-A Receptor Agonists; D011799:Quinazolines; D011963:Receptors, GABA-A