title: Iron-catalyzed cross-coupling of alkenyl sulfides with Grignard reagents.
abstract: [reaction: see text] The iron-catalyzed cross-coupling reaction of alkenyl sulfides with Grignard reagents is described. While the cross-coupling proceeds efficiently at alkenyl-S bonds, almost no cross-coupling takes place at aryl-S bonds, attesting to a unique selectivity of iron catalysis. The beneficial effect of potentially coordinating 2-pyrimidyl group on sulfur is also described.
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510, Japan. itami@sbchem.kyoto-u.ac.jp
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Itami
authors.forename: Shohei
authors.initials: S
authors.lastname: Higashi
authors.forename: Masahiro
authors.initials: M
authors.lastname: Mineno
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Yoshida