title: Helicobacter pylori in children who are prone to upper respiratory tract infections.
abstract: OBJECTIVE
  To examine the presence of Helicobacter pylori infection in children with recurrent upper respiratory infections, including acute otitis media.
  
  
  METHODS
  A prospective clinical trial.
  
  
  METHODS
  Tertiary referral center.
  
  
  METHODS
  A total of 20 children who were prone to upper respiratory infections and acute otitis and who were admitted for elective adenoidectomy and/or tympanostomy were included in the study.
  
  
  METHODS
  Samples of adenoid tissue and middle ear fluid were cultured for H pylori. Serologic analysis and fecal antigen detection testing were also carried out to determine the presence of H pylori.
  
  
  RESULTS
  The results of serologic and antigen detection tests were positive for H pylori in 4 children (20%), but cultures of adenoid tissue and middle ear fluid samples were negative for H pylori in all children.
  
  
  CONCLUSIONS
  An association between H pylori infection and recurrent upper respiratory infections and otitis media could not be established.
authors.affiliation: Department of Otorhinolaryngology, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland. anne.pitkaranta@hus.fi
authors.forename: Anne
authors.initials: A
authors.lastname: Pitkäranta
authors.forename: Kaija-Leena
authors.initials: KL
authors.lastname: Kolho
authors.forename: Hilpi
authors.initials: H
authors.lastname: Rautelin
mesh_terms: D000208:Acute Disease; D000233:Adenoidectomy / Q000379:methods; D017677:Age Distribution; D000942:Antigens, Bacterial / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D004198:Disease Susceptibility; D005243:Feces / Q000382:microbiology; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000453:epidemiology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D015994:Incidence; D008297:Male; D008876:Middle Ear Ventilation / Q000379:methods; D010033:Otitis Media / Q000453:epidemiology / Q000382:microbiology* / Q000601:surgery; D011379:Prognosis; D011446:Prospective Studies; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000382:microbiology*; D012307:Risk Factors; D017678:Sex Distribution
chemical_list: D000942:Antigens, Bacterial