title: Radiofrequency tumor ablation: insight into improved efficacy using computer modeling.
abstract: OBJECTIVE
  To use computer modeling of the Bio-Heat equation to demonstrate factors influencing RF ablation tissue heating.
  
  
  CONCLUSIONS
  Computer modeling demonstrates the importance of energy deposition, tumor and background tissue electrical and thermal conductivity, and perfusion on RF ablation outcomes.
authors.affiliation: Department of Radiology, Beth Israel Deaconess Medical Center, 1 Deaconess Rd., WCC 308B, Boston, MA 02215, USA.
authors.forename: Zhengjun
authors.initials: Z
authors.lastname: Liu
authors.forename: S Melvyn
authors.initials: SM
authors.lastname: Lobo
authors.forename: Stanley
authors.initials: S
authors.lastname: Humphries
authors.forename: Clare
authors.initials: C
authors.lastname: Horkan
authors.forename: Stephanie A
authors.initials: SA
authors.lastname: Solazzo
authors.forename: Andrew U
authors.initials: AU
authors.lastname: Hines-Peralta
authors.forename: Robert E
authors.initials: RE
authors.lastname: Lenkinski
authors.forename: S Nahum
authors.initials: SN
authors.lastname: Goldberg
mesh_terms: D017115:Catheter Ablation; D003198:Computer Simulation; D004553:Electric Conductivity; D020342:Finite Element Analysis; D006801:Humans; D009336:Necrosis; D015641:Radiography, Interventional