[Age-related characteristics of the thymus and adrenal cortex function in CBA mice immunized by T-dependent antigen].
The thymic serum factor (FTS) titer and corticosterone level in blood of adult and old CBA mice after immunization by T-dependent antigen was investigated. It has been revealed that in adult mice these indices influenced by phase changes in dynamics of immunization whereas in old mice fluctuations of FFS and corticosterone levels were monotonous. In both adult and old mice the correlation exists between thymic hormone and corticosterone. The increasing of thymic function by thymaline administration did not improve the dynamics of FTS titer and corticosterone level in immunized old mice.
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D000311:Adrenal Glands / Q000276:immunology*; D000375:Aging / Q000276:immunology*; D000818:Animals; D000941:Antigens / Q000276:immunology; D003345:Corticosterone / Q000097:blood / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D007114:Immunization; D051379:Mice; D008808:Mice, Inbred CBA; D013601:T-Lymphocytes / Q000276:immunology*; D013935:Thymic Factor, Circulating / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology*; D013951:Thymus Hormones / Q000494:pharmacology
D000941:Antigens; D013951:Thymus Hormones; C032805:thymalin; D013935:Thymic Factor, Circulating; D003345:Corticosterone