title: [Age's influence in superficial bladder cancer's behaviour].
abstract: BACKGROUND
  Transitional bladder cancer is infrequent in younger people. The tumor's aggressiveness in this population is subject of discussion. We present our experience.
  
  
  METHODS
  551 primary tumors, with at least one year of follow-up. Group A (less than 41 years old), Group B (bigger than 40 years old). We compare, stage, grade, lymphatic permeation, multiplicity, recurrence, progression, sex, T.L.E. (time free of disease), volume. We do uni and multivariate analysis.
  
  
  RESULTS
  17 tumors in younger than 41 years (2.1%). The recurrence rate is 11.8% in Group A and 36% in Group B (p .041). Progression rate: 0% in A and 4.1% in B (p .253). In Group A, T1 tumors (13.3% vs. 39%), G2 tumors (0% vs. 36.7%); withouts in lymphatic permeation (0% vs. 35%) and solitary tumors (13.3% vs. 35.3%) have statistically less recurrence. In univariate analysis we appreciate statistical differences in relation with grade (p .002) and sex (p .011). In multivariate analysis, stage, "group of age" and prophylactic treatment are independent variables for recurrence, and grade for progression.
  
  
  CONCLUSIONS
  In younger than 41 years old: Less pathologic aggressivity (0% G3); Group of age is independent prognostic variable for recurrence, but not p for progression, despite a "less aggressive behaviour": 11.8% recurrence, 0% progression; T.L.E. bigger (one year more); Higher incidence in women (41% vs. 11%); Less recurrence in T1 tumors (13.3% vs. 39%), G2 tumors (0% vs. 36.7%) and solitary tumors (13.3% vs. 35.32%).
authors.affiliation: Servicio de Urología, Hospital Universitario Virgen Macarena de Sevilla, Fundación Joaquín Albarrán.
authors.forename: J L
authors.initials: JL
authors.lastname: Moyano Calvo
authors.forename: M
authors.initials: M
authors.lastname: Gutiérrez González
authors.forename: A
authors.initials: A
authors.lastname: Pérez-Lanzac Llorca
authors.forename: A
authors.initials: A
authors.lastname: Molina Carranza
authors.forename: J L
authors.initials: JL
authors.lastname: Alvarez-Ossorio Fernández
authors.forename: E
authors.initials: E
authors.lastname: Sánchez Sánchez
authors.forename: J
authors.initials: J
authors.lastname: Castiñeiras Fernández
mesh_terms: D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000453:epidemiology* / Q000473:pathology; D015653:Cystectomy; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D012008:Recurrence; D016019:Survival Analysis; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology* / Q000473:pathology