title: Acute myopia induced by topiramate: report of a case and review of the literature.
abstract: Topiramate, a new anticonvulsant, is also used for the prophylaxis of migraine and cluster headache. A serious but not often discussed side effect of the drug is the development of acute myopia and acute angle-closure glaucoma in the early stage of therapy that subsides rapidly with prompt discontinuation. One such case is reported here and the relevant literature in this regard is also reviewed.
authors.affiliation: Department of Neurology, Calcutta National Medical College and Hospital, Kolkata 700-042, West Bengal, India. kalyanbrb@rediffmail.com
authors.forename: Kalyan B
authors.initials: KB
authors.lastname: Bhattacharyya
authors.forename: S
authors.initials: S
authors.lastname: Basu
mesh_terms: D000208:Acute Disease; D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects*; D005260:Female; D005632:Fructose / Q000009:adverse effects* / Q000031:analogs & derivatives*; D006261:Headache / Q000188:drug therapy*; D006801:Humans; D009216:Myopia / Q000139:chemically induced*; D000077236:Topiramate
chemical_list: D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose