title: Bilateral idiopathic multifocal retinal pigment epithelium detachments in otherwise healthy middle-aged adults: a clinicopathologic study.
abstract: OBJECTIVE
  To present the results of a clinicopathologic study of patients with bilateral idiopathic multifocal serous retinal pigment epithelial detachments (RPEDs).
  
  
  METHODS
  Retrospective review of the medical records of three middle-aged patients with innumerable RPEDs. The eye of one patient was available for histopathologic examination.
  
  
  RESULTS
  The presence of multiple serous RPEDs was verified with fluorescein angiography and optical coherence tomography in two patients and by histopathologic examination of one eye of a third patient, who developed a submacular hematoma and vitreous hemorrhage caused by a focal area of choroidal neovascularization.
  
  
  CONCLUSIONS
  No cause for the multifocal serous RPEDs was found.
authors.affiliation: Department of Ophthalmology, Vanderbilt University Medical School, Nashville, Tennessee 37232-8808, USA.
authors.forename: J Donald M
authors.initials: JD
authors.lastname: Gass
authors.forename: Susan B
authors.initials: SB
authors.lastname: Bressler
authors.forename: Levent
authors.initials: L
authors.lastname: Akduman
authors.forename: Joseph
authors.initials: J
authors.lastname: Olk
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Caskey
authors.forename: Lorenz E
authors.initials: LE
authors.lastname: Zimmerman
mesh_terms: D000328:Adult; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012163:Retinal Detachment / Q000209:etiology / Q000473:pathology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence