title: Laparoscopic-assisted approach in rectal cancer patients: lessons learned from >200 patients.
abstract: BACKGROUND
  The applicability of laparoscopic surgery in the treatment of colorectal diseases is still controversial. Early reports on laparoscopic-assisted colectomy in patients with colon cancer suggested that it minimizes surgical trauma, decreases perioperative complications, and leads to a more rapid recovery. To our knowledge, no previous studies have compared the laparoscopic vs the open approach in rectal cancer. The aim of this paper was to assess the results of laparoscopic techniques in patients with rectal cancer.
  
  
  METHODS
  From March 1998 to February 2003, all patients admitted to our unit with adenocarcinoma of the rectum were evaluated for surgery by the laparoscopic approach.
  
  
  RESULTS
  A total of 220 patients with a mean age of 67.3 years were included in the study. One hundred thirty patients (59%) were treated with neoadjuvant chemoradiotherapy. In >75% of the patients, a surgical procedure with sphincter preservation was performed. The rate of conversion to the open approach was 20%. Ten patients had intraoperative complications. Fifty-eight patients (26.3%) developed postoperative complications. The length of hospital stay was 6.8 days. The distribution of tumor stages was as follows: stage I, 16.81%; stage II, 33.6%; stage III, 26.36%; stage IV, 19.09%. The mean number of lymph nodes was 13.8. The incidence of local relapse was 5.3%, with a follow-up of 18 months.
  
  
  CONCLUSIONS
  Laparoscopic surgery can be safely performed in patients with adenocarcinoma of the rectum with good short-term results. Randomized controlled trials are needed to confirm these results.
authors.affiliation: Department of Gastrointestinal Surgery, Institute of Digestive Diseases, Hospital Clinic, University of Barcelona, Villarroel 170, 08036, Barcelona, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Delgado
authors.forename: D
authors.initials: D
authors.lastname: Momblán
authors.forename: L
authors.initials: L
authors.lastname: Salvador
authors.forename: R
authors.initials: R
authors.lastname: Bravo
authors.forename: A
authors.initials: A
authors.lastname: Castells
authors.forename: A
authors.initials: A
authors.lastname: Ibarzabal
authors.forename: J M
authors.initials: JM
authors.lastname: Piqué
authors.forename: A M
authors.initials: AM
authors.lastname: Lacy
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D012004:Rectal Neoplasms / Q000601:surgery*