title: Body temperature - a marker of infarct size in the era of early reperfusion.
abstract: We measured body temperature in 40 consecutive patients treated for a first ST elevation acute myocardial infarction (AMI) with primary percutaneous coronary interventions. Left ventricular function was assessed by echocardiography, and blood samples were drawn for highly sensitive C-reactive protein (hs-CRP), white blood cell (WBC) count, fibrinogen, creatine kinase (CK), and cardiac troponin I levels (cTnI). The median (25th, 75th quartiles) peak 24-hour temperature was 37.4 degrees C (36.9 degrees C, 37.6 degrees C). Variables significantly associated with peak 24-hour temperature were CK (p = 0.01, r = 0.42), wall motion index (p = 0.01, r = 0.41), hs-CRP (p = 0.01, r = 0.41), and cTnI (p = 0.03, r = 0.35). There was no significant correlation between peak 24-hour temperature and WBC count (p = 0.39, r = 0.14) and fibrinogen (p = 0.12, r = 0.21). Thus, peak 24-hour body temperature after ST elevation AMI probably reflects infarct size rather than a nonspecific inflammatory response.
authors.affiliation: Rabin Medical Center, Petah-Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Israel.
authors.forename: Itsik
authors.initials: I
authors.lastname: Ben-Dor
authors.forename: Moti
authors.initials: M
authors.lastname: Haim
authors.forename: Eldad
authors.initials: E
authors.lastname: Rechavia
authors.forename: Daniel
authors.initials: D
authors.lastname: Murininkas
authors.forename: Merav
authors.initials: M
authors.lastname: Nahon
authors.forename: Daniella
authors.initials: D
authors.lastname: Harell
authors.forename: Avital
authors.initials: A
authors.lastname: Porter
authors.forename: Zaza
authors.initials: Z
authors.lastname: Iakobishvili
authors.forename: Erez
authors.initials: E
authors.lastname: Scapa
authors.forename: Alexander
authors.initials: A
authors.lastname: Battler
authors.forename: David
authors.initials: D
authors.lastname: Hasdai
mesh_terms: D015415:Biomarkers / Q000097:blood; D001831:Body Temperature / Q000502:physiology*; D002097:C-Reactive Protein / Q000032:analysis; D015331:Cohort Studies; D003402:Creatine Kinase / Q000097:blood; D004452:Echocardiography; D005260:Female; D005334:Fever / Q000503:physiopathology*; D005340:Fibrinogen / Q000032:analysis; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology; D009203:Myocardial Infarction / Q000097:blood / Q000473:pathology* / Q000503:physiopathology; D015425:Myocardial Reperfusion; D011446:Prospective Studies; D019210:Troponin I / Q000097:blood; D016277:Ventricular Function, Left / Q000502:physiology
chemical_list: D015415:Biomarkers; D019210:Troponin I; D005340:Fibrinogen; D002097:C-Reactive Protein; D003402:Creatine Kinase