title: Unusual clinical course of metachronous melanomas of the upper digestive system.
abstract: Melanoma of the gastrointestinal tract is a rare, highly malignant neoplasm of poor prognosis. This is description of an unusual case of surgically treated patient with two metachronous malignant melanomas of the stomach and the esophagus. The former lesion was located in the cardia and effectively treated with R0 total gastrectomy. The latter was recognized after 67 mo and appeared as irregular, flat, pigmented areas located in the mid esophagus. Subtotal esophagectomy via right-sided thoracotomy, laparotomy and left-sided cervicotomy was performed, but neoplastic cells were found in distal margin (R1). Fourteen months after esophagectomy multiple lung metastases were detected. Patient died 2 mo later.
authors.affiliation: 2nd Department of General Surgery, Skubiszewski Medical University of Lublin, Staszica 16, 20-081, Lublin, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Dabrowski
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Zinkiewicz
authors.forename: Justyna
authors.initials: J
authors.lastname: Szumilo
authors.forename: Witold
authors.initials: W
authors.lastname: Zgodzinski
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Cwik
authors.forename: Tomasz
authors.initials: T
authors.lastname: Skoczylas
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Wallner
mesh_terms: D004938:Esophageal Neoplasms / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008545:Melanoma / Q000473:pathology* / Q000556:secondary; D008875:Middle Aged; D011379:Prognosis; D013274:Stomach Neoplasms / Q000473:pathology*