title: Basaloid squamous carcinoma of the hypopharynx with an extensive spindle cell component exhibiting a pedunculated polypoid mass.
abstract: We report a case of basaloid squamous carcinoma of the hypopharynx with an extensive spindle cell component in an 82-year-old man. The tumor (4.0 x 2.5 x 2.2 cm) was a pedunculated polypoid mass that was attached to the left pyriform sinus. Histologically, most (70%) of the tumor was composed of malignant spindle cell proliferation, and the rest (30%) was basaloid squamous carcinoma. Some of the spindle cells were positive for cytokeratins. The preoperative histologic diagnosis was difficult because the endoscopic biopsy specimens showed only spindle cell proliferation. This is an unusual presentation of basaloid squamous carcinoma of the head and neck.
authors.affiliation: Department of Pathology, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Tokuhiro
authors.initials: T
authors.lastname: Kimura
authors.forename: Makio
authors.initials: M
authors.lastname: Mukai
authors.forename: Akihiro
authors.initials: A
authors.lastname: Shiotani
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Moro
authors.forename: Asako
authors.initials: A
authors.lastname: Ikeda
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Okada
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002281:Carcinoma, Basosquamous / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D008297:Male