title: Synthesis and antibacterial activity of adamantyl substituted pyrimidines.
abstract: A series of new S-substituted 6-adamantylpyrimidines were prepared by alkylation on the thiol groups in 6-adamant-1-yl-2-methyl-3H-pyrimidine-4-thione and 6-adamant-1-yl-2-thioxo-2,3-dihydro-1H-pirymidin-4-one, respectively. Then, these compounds were tested against several bacterial strains as well as fungi.
authors.affiliation: Warsaw University of Technology, Faculty of Chemistry, 00-662 Warsaw.
authors.forename: Barbara
authors.initials: B
authors.lastname: Orzeszko
authors.forename: Agnieszka Ewa
authors.initials: AE
authors.lastname: Laudy
authors.forename: Bohdan Jerzy
authors.initials: BJ
authors.lastname: Starościak
authors.forename: Andrzej
authors.initials: A
authors.lastname: Orzeszko
authors.forename: Zygmunt
authors.initials: Z
authors.lastname: Kazimierczuk
mesh_terms: D000218:Adamantane / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D011743:Pyrimidines; D000218:Adamantane