title: Kikuchi-Fujimoto disease associated with mixed connective tissue disease.
abstract: Kikuchi-Fujimoto disease is characterized by painful cervical lymphadenopathy and constitutional symptoms. Microscopical study of lymph nodes shows focal areas of non-suppurative necrosis with histiocytic and plasmacytoid cell infiltrates. The course is usually benign. Often primitive, necrotising histiocytic lymphadenopathy may be associated with autoimmune disorders. We describe the case of a 30-year-old female patient with two 15-day courses of Kikuchi-Fujimoto disease flares within a period of 3 months, occurring in association with mixed connective tissue disease.
authors.affiliation: Department of Infectious and Tropical Diseases, Hopital Necker-Enfants Malades, Paris, France.
authors.forename: N
authors.initials: N
authors.lastname: Pallet
authors.forename: L
authors.initials: L
authors.lastname: Aaron
authors.forename: F
authors.initials: F
authors.lastname: Larousserie
authors.forename: A
authors.initials: A
authors.lastname: Therby
authors.forename: B
authors.initials: B
authors.lastname: Dupont
authors.forename: J-P
authors.initials: JP
authors.lastname: Viard
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D005500:Follow-Up Studies; D020042:Histiocytic Necrotizing Lymphadenitis / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008947:Mixed Connective Tissue Disease / Q000150:complications* / Q000175:diagnosis / Q000473:pathology*; D012075:Remission, Spontaneous; D018570:Risk Assessment; D012720:Severity of Illness Index