Myocardial oxygen consumption index in patients with coronary artery disease.
One hundred and thirty-six men with coronary artery disease were randomly assigned to a hospital-based or home-based exercise program of 3 sessions per week. A treadmill test was carried out with the modified Naughton protocol. After 3 months, 125 patients (92%) with a mean age of 55 +/- 11 years had completed the study. Maximum workload achieved increased by 65% [(12.40 +/- 1.32 vs. 7.50 +/- 0.85 metabolic equivalent units (METs)] in the hospital-based group, and by 17% (8.86 +/- 0.9 vs. 7.56 +/- 0.78 METs) in the home-based group ( p = 0.0001). The heart rate-blood pressure product, an index of myocardial oxygen consumption, decreased at rest by 19% in the hospital-based group but was unchanged in the home-based group ( p = 0.0001). The heart rate-blood pressure product at 5 and 7 METs activity level decreased 28% and 26%, respectively, in the hospital-based group vs. 8% and 2% in the home-based group ( p = 0.0001). It was concluded that hospital-based exercise training in patients with coronary artery disease improves functional capacity and decreases the myocardial oxygen consumption index at rest and during exercise.
Arya
Arash
A
Department of Cardiology, Rajaie Cardiovascular Medical Center, Mellat Park, Vali-Asr Avenue, Tehran 19969-11151, Iran. arya@rhc.ac.ir
Maleki
Majid
M
Noohi
Fereydoon
F
Kassaian
Ebrahim
E
Roshanali
Farideh
F
D000328:Adult; D000368:Aged; D016507:Cardiology Service, Hospital; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000378:metabolism / Q000534:rehabilitation* / Q000601:surgery; D005081:Exercise Therapy; D018575:Home Care Services, Hospital-Based; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000378:metabolism / Q000534:rehabilitation*; D009206:Myocardium / Q000378:metabolism*; D010101:Oxygen Consumption