title: Treatment of multiple apocrine hidrocystomas with trichloroacetic acid.
abstract: The apocrine hidrocystoma is a benign adenomatous cystic proliferation derived from apocrine glands, which frequently occurs in periocular tissues. These cystadenomas may occur bilaterally, in multiple disfiguring confluent groups on both the upper and lower lids. Although these lesions have been treated successfully with meticulous surgical extirpation and electrosurgery, this report describes the successful treatment of two patients, each with multiple large (>7 mm) periocular apocrine hidrocystomas by either chemical ablation of the cystic epithelium with trichloroacetic acid (TCA) or surgical excision. Examination of the cysts at 1, 3, and 6 months after TCA treatment revealed well-healed lesions without cyst recurrence. Most of the TCA-treated cysts resolved completely, without leaving any trace to clinical examination. Treatment of cysts with TCA was technically simpler and much less time-consuming than surgical excision. The treatment of large apocrine hidrocystomas with TCA is an effective and expeditious method of treating these disfiguring and recalcitrant lesions.
authors.affiliation: Oregon Health Sciences University, Casey Eye Institute, Portland, Oregon 79239-4197, USA.
authors.forename: Roger A
authors.initials: RA
authors.lastname: Dailey
authors.forename: Stanley M
authors.initials: SM
authors.lastname: Saulny
authors.forename: Robert N
authors.initials: RN
authors.lastname: Tower
mesh_terms: D000368:Aged; D001050:Apocrine Glands / Q000187:drug effects* / Q000473:pathology; D005142:Eyelid Neoplasms / Q000188:drug therapy* / Q000473:pathology; D018251:Hidrocystoma / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy* / Q000473:pathology; D013544:Sweat Gland Neoplasms / Q000188:drug therapy* / Q000473:pathology; D014238:Trichloroacetic Acid / Q000627:therapeutic use*
chemical_list: D014238:Trichloroacetic Acid