title: Comparison of short-term in vitro fluoride release and recharge from four different types of pit-and-fissure sealants.
abstract: OBJECTIVE
  The purpose of this in vitro study was to assess the effects of four commercial fluoride-containing pit-and-fissure sealants on caries prevention.
  
  
  METHODS
  Four sealants containing fluoride, Fuji III, Fuji III LC (GC Co., Tokyo), Teethmate F-1 (Kuraray Medical Co., Osaka) and Helioseal F (Vivadent Co., Liechtenstein) were used to investigate fluoride release and recharge. Disk-shaped specimens prepared from each material were immersed in distilled water at a temperature of 37 degrees C. After seven days, acidulated phosphate fluoride solution (APF) was applied to each specimen, and it was then again immersed in distilled water for 14 days. We then determined how much fluoride had been released into the immersing water. Fuji III LC was used with APF solution to investigate the fluoride uptake.
  
  
  RESULTS
  Fuji III had the highest fluoride release, and Fuji III LC had the highest fluoride recharge. Helioseal F and Teethmate F-1 had almost no fluoride recharge. Fuji III LC/APF had a higher fluoride uptake to enamel than Fuji III LC.
  
  
  CONCLUSIONS
  These results suggest that GIC-sealants in the oral cavity can serve as a fluoride reservoir and contribute to retaining a low fluoride level in oral fluids, thereby preventing caries.
authors.affiliation: Department of Epidemiology and Public Health, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba 261-8502, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Koga
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kameyama
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsukubo
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Hirai
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Takaesu
mesh_terms: D000149:Acidulated Phosphate Fluoride / Q000737:chemistry; D000818:Animals; D002327:Cariostatic Agents / Q000737:chemistry* / Q000493:pharmacokinetics; D002417:Cattle; D003188:Composite Resins / Q000737:chemistry; D003743:Dental Enamel / Q000378:metabolism; D004058:Diffusion; D005459:Fluorides / Q000737:chemistry* / Q000493:pharmacokinetics; D005899:Glass Ionomer Cements / Q000737:chemistry; D008422:Materials Testing; D010895:Pit and Fissure Sealants / Q000737:chemistry*; D013696:Temperature; D013997:Time Factors; D014867:Water / Q000737:chemistry
chemical_list: D002327:Cariostatic Agents; D003188:Composite Resins; D005899:Glass Ionomer Cements; D010895:Pit and Fissure Sealants; C099291:teethmate-FTM; D014867:Water; C059908:Helioseal; D000149:Acidulated Phosphate Fluoride; D005459:Fluorides