title: Mitral valve prolapse in Cavalier King Charles spaniel: a review and case study.
abstract: A 5 year-old spayed female Cavalier King Charles Spaniel was presented after a 3- to 5-day onset of severe respiratory distress. The dog also had a history of several episodes of syncope prior to presentation. A comprehensive diagnostic investigation revealed a midsystolic click sound on cardiac auscultation, signs of left sided cardiac enlargement in ECG and thoracic radiography, mitral valvular leaflet protrusion into left the atrium, decreased E-point-to septal separation (EPSS) and mitral regurgitated flow in echocardiography, all of which are characteristic signs of mitral valvular prolapse. After intensive care with diuretics [corrected] and a vasodilator with oxygen supplement, the condition of the dog was stabilized. The dog was then released and is being medicated with angiotensin converting enzyme (ACE) inhibitor with regular follow-up.
authors.affiliation: Victor Chang Cardiac Research Institute, 384 Victoria St. Darlinghurst, Sydney, NSW 2010, Australia. c.hyun@victorchang.unsw.edu.au
authors.forename: Changbaig
authors.initials: C
authors.lastname: Hyun
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000818:Animals; D004232:Diuretics / Q000627:therapeutic use; D004283:Dog Diseases / Q000175:diagnosis* / Q000188:drug therapy; D004285:Dogs; D004656:Enalapril / Q000627:therapeutic use; D005260:Female; D005665:Furosemide / Q000627:therapeutic use; D008945:Mitral Valve Prolapse / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D004232:Diuretics; D004656:Enalapril; D005665:Furosemide