Transitory sleep spindles impairment in deep cerebral venous thrombosis.
Sleep spindles may be affected by thalamic or hemispheric ischemic stroke. However, spindles reduction and their relationship with K-complexes following deep cerebral venous thrombosis have not been reported. An 18-year-old woman suffered from a deep cerebral venous thrombosis with vasogenic oedema located predominantly in the thalami. Stage 2 sleep EEG recorded in acute setting showed preservation of K-complexes but absent 12-14 Hz sleep spindles, which were replaced by spindle-like theta oscillations. One month later, the patient having completely recovered, sleep spindles were normally seen on the control EEG. This case illustrates that deep cerebral venous thrombosis, through a vasogenic oedema, may transiently affect thalamic functions such as spindles generation. Furthermore, thalamic impairment may lead to dissociation of spindle and K-complex activity.
Rossetti
Andrea O
AO
Service de Neurologie, Centre Hospitalier Universitaire Vaudois, Neurologie BH 07, 1011 Lausanne, Switzerland.
Maeder-Ingvar
Malin
M
Reichhart
Marc D
MD
Despland
Paul-André
PA
Bogousslavsky
Julien
J
D000293:Adolescent; D004594:Electrophysiology; D005260:Female; D006801:Humans; D020767:Intracranial Thrombosis / Q000503:physiopathology*; D012890:Sleep / Q000502:physiology*; D013997:Time Factors; D020246:Venous Thrombosis / Q000503:physiopathology*