Fibrous hamartoma of infancy: a case report with associated cytogenetic findings.
A 2-month-old male infant presented with a subcutaneous mass on the left middle finger; the mass had been present since birth. This was treated with local excision, and there has been no recurrence. Histology revealed the typical features of a fibrous hamartoma. Cytogenetic studies revealed a reciprocal translocation, t(2;3)(q31;q21), as the sole abnormality. To our knowledge, this is the first report of the cytogenetic findings in fibrous hamartoma, and it suggests that this lesion represents a benign neoplasm.
Lakshminarayanan
Renuka
R
Departmentsof Pathology and Laboratory Medicine, University of California Davis Medical Center, Sacramento 95817, USA.
Konia
Thomas
T
Welborn
Jeanna
J
D002889:Chromosomes, Human, Pair 2; D005385:Fingers; D006222:Hamartoma / Q000151:congenital* / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D012983:Soft Tissue Neoplasms / Q000151:congenital* / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic