title: Parapharyngeal granular cell tumour: a unique surgical challenge.
abstract: A granular cell tumour is a rare lesion of probable nerve sheath origin. It is typically benign but up to seven per cent may be malignant. Since its original description in the tongue in 1926, the tumour has been reported to occur at many other sites in the body. The authors report a case of a 49-year-old African woman with an oro-naso-parapharyngeal granular cell neoplasm causing mild dysphagia. The location of this tumour, which has not been reported previously, posed a unique surgical challenge. An initial attempt to remove the lesion transorally was only partially successful because it was too tough and adherent for conventional surgical dissecting instruments. Complete resection, however, was achieved with a carbon dioxide laser via the same approach. This information may be helpful in the management of other similar cases in the future.
authors.affiliation: Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK. RandM.Persaud@ukgateway.net
authors.forename: R
authors.initials: R
authors.lastname: Persaud
authors.forename: S
authors.initials: S
authors.lastname: Tudge
authors.forename: K
authors.initials: K
authors.lastname: Amonoo-Kuofi
authors.forename: T
authors.initials: T
authors.lastname: Beale
authors.forename: P
authors.initials: P
authors.lastname: O'Flynn
mesh_terms: D003680:Deglutition Disorders / Q000209:etiology; D005260:Female; D016586:Granular Cell Tumor / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D010610:Pharyngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome