title: Stereoselective electrochemical carboxylation: 2-phenylsuccinates from chiral cinnamic acid derivatives.
abstract: Chiral 2-phenyl succinic ester derivatives have been obtained under mild conditions, in short times and with satisfactory yields by electrochemical reduction of chiral cinnamic acid derivatives under a CO2 atmosphere. When 4R-(diphenylmethyl)-oxazolidin-2-one was used as a chiral auxiliary the two diastereoisomers could be easily separated by flash chromatography and the R-isomer was obtained as major product.
authors.affiliation: Dip. Ingegneria Chimica, Materiali, Materie Prime e Metallurgia, Universita La Sapienza, via Castro Laurenziano, 7, I-00161, Roma, Italy.
authors.forename: Monica
authors.initials: M
authors.lastname: Orsini
authors.forename: Marta
authors.initials: M
authors.lastname: Feroci
authors.forename: Giovanni
authors.initials: G
authors.lastname: Sotgiu
authors.forename: Achille
authors.initials: A
authors.lastname: Inesi