[The role of chemokines in the pathogenesis of restenosis].
In the article the role of immunologic cells and hemostatic factors in the formation of atherosclerosis was described. Attention was paid to restenosis in patients undergoing percutaneous transluminal coronary angioplasty (PTCA), a phenomenon that occurs in 20-50% of these patients. Among many factors that contribute to restenosis more attention is paid lately to the role of chemokines. The physiology role of chemokines was described and the contribution of monocyte chemoattractant protein-1 to restenosis after PTCA.
Latacz
Paweł
P
Klinika Choroby Wieńcowej, Instytut Kardiologii Collegium Medicum, Uniwersytetu Jagiellońskiego, Kraków. lataczp@poczta.onet.pl
Piwowarska
Wiesława
W
D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects; D018932:Chemokine CCL2 / Q000378:metabolism; D018925:Chemokines / Q000378:metabolism*; D003324:Coronary Artery Disease / Q000378:metabolism* / Q000628:therapy; D023903:Coronary Restenosis / Q000378:metabolism*; D006801:Humans
D018932:Chemokine CCL2; D018925:Chemokines