Bilateral anterior granulomatous uveitis associated with cutaneous Rosai-Dorfman disease.
BACKGROUND
Rosai-Dorfman disease (RDD) is a benign, rare, histiocytic disorder of unknown etiology. We describe the case of a 61-year-old woman who presented to the ophthalmology clinic with bilateral granulomatous anterior uveitis.


METHODS
The uveitis was controlled on topical prednisolone acetate 1%. One month after presentation, she developed generalized macules and papules, and dermatologic and systemic evaluations were performed.


RESULTS
On the basis of skin biopsy, purely cutaneous RDD was established.


CONCLUSIONS
Anterior granulomatous uveitis may be the presenting sign of cutaneous RDD. Consultation is necessary for accurate diagnosis.
Gaviria
Juan G
JG
Department of Ophthalmology, University of Texas Health Science Center at San Antonio, 78229-3900, USA. juangaviria@lycos.com
Johnson
Daniel A
DA
Kinney
Marsha C
MC
Proffer
Liana H
LH
Losi-Sasaki
Jacqueline M
JM
Kraus
Eric W
EW
D005260:Female; D006099:Granuloma / Q000209:etiology*; D015618:Histiocytosis, Sinus / Q000150:complications* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D012871:Skin Diseases / Q000150:complications* / Q000473:pathology; D014603:Uveal Diseases / Q000209:etiology*; D014606:Uveitis, Anterior / Q000209:etiology*