title: Influence of Carisolv on resin adhesion for two different adhesive systems to sound human primary dentin and young permanent dentin.
abstract: OBJECTIVE
  This study evaluated the influence of Carisolv (Medi Team) for resin adhesion to sound human primary and young permanent dentin.
  
  
  METHODS
  The buccal surfaces of 28 primary molars and 64 premolars were used. Two adhesive systems and resin composites were used; SE: Clearfil SE (Kuraray) and Clearfil APX (Kuraray), and SB: Single Bond (3M) and Z250 (3M). Six groups were prepared. Groups 1-2 were primary dentin and Groups 3-6 were permanent dentin. Groups 1 and 3: SE was used. Groups 2 and 4: treated with Carisolv and then primed, SE was used. Group 5: SB was used. Group 6: treated with Carisolv and then etched, SB was used. The microstructural effects of primer or etchant, and Carisolv plus primer or etchant applied to dentin were evaluated by SEM. In addition, the microstructure of the resin-dentin interfaces of each group was studied using SEM. Shear bond strengths (SBS) were tested, and the failed surfaces were observed using SEM. Data was statistically analyzed using ANOVA with subsequent application of Fisher's PLSD at p<0.05.
  
  
  RESULTS
  The mean SBS (unit: MPa) of Groups 1-6 were: 27.8, 19.2, 21.3, 21.7, 6.7 and 7.6. The SBS of Group 2 was significantly lower than that of Group 1. There was no significant difference of the SBS among Groups 1 and 4, 2, 3 and 4, and 5 and 6. In SE groups, the hybrid layer for primary dentin was thicker than that for permanent dentin.
  
  
  CONCLUSIONS
  Carisolv treatment before priming significantly decreased the SBS to primary dentin in SE groups, but did not influence the SBS to permanent dentin in both SE and SB groups.
authors.affiliation: Department of Developmental and Reconstructive Medicine, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1, Sakamoto, Nagasaki, 852-8588 Japan. hosoya@net.nagasaki-u.ac.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Hosoya
authors.forename: H
authors.initials: H
authors.lastname: Shinkawa
authors.forename: G W
authors.initials: GW
authors.lastname: Marshall
mesh_terms: D000134:Acid Etching, Dental; D001641:Bicuspid; D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry; D003188:Composite Resins / Q000737:chemistry*; D001840:Dental Bonding; D003737:Dental Cavity Preparation / Q000379:methods*; D003804:Dentin / Q000648:ultrastructure*; D017220:Dentin-Bonding Agents / Q000737:chemistry*; D018698:Glutamic Acid / Q000627:therapeutic use*; D006801:Humans; D007930:Leucine / Q000627:therapeutic use*; D008239:Lysine / Q000627:therapeutic use*; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D008963:Molar; D019279:Resin Cements / Q000737:chemistry; D013314:Stress, Mechanical; D013499:Surface Properties; D014094:Tooth, Deciduous / Q000648:ultrastructure*
chemical_list: C119934:Carisolv; C112828:Clearfil AP-X; C438313:Clearfil SE Bond; D003188:Composite Resins; D017220:Dentin-Bonding Agents; C444701:Filtek Z250; D008689:Methacrylates; D019279:Resin Cements; C115612:single bond; D018698:Glutamic Acid; D017438:Bisphenol A-Glycidyl Methacrylate; D007930:Leucine; D008239:Lysine