title: [Modification of hyaluronic acid with aromatic amino acids].
abstract: Hyaluronic acid was modified with aromatic amino acids (5-aminosalicylic, 4-aminosalicylic, anthranilic, and p-aminobenzoic) in the presence of 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide. The modified glycans contained 9-43% of arylamide groups and 10-33% of isoureidocarbonyl groups depending on the nature of the amino acid. Reduction with sodium borohydride allowed the conversion of isoureidocarbonyl groups into hydroxymethyl groups.
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Ponedel'kina
authors.forename: V N
authors.initials: VN
authors.lastname: Odinokov
authors.forename: E S
authors.initials: ES
authors.lastname: Vakhrusheva
authors.forename: M T
authors.initials: MT
authors.lastname: Golikova
authors.forename: L M
authors.initials: LM
authors.lastname: Khalilov
authors.forename: U M
authors.initials: UM
authors.lastname: Dzhemilov
mesh_terms: D024322:Amino Acids, Aromatic / Q000737:chemistry*; D002234:Carbodiimides / Q000737:chemistry*; D006801:Humans; D006820:Hyaluronic Acid / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D024322:Amino Acids, Aromatic; D002234:Carbodiimides; D006820:Hyaluronic Acid