Palladium-catalyzed alpha-arylation of sulfoximines.
[reaction: see text] Palladium-catalyzed alpha-arylation of N-benzoyl sulfoximine ethyl ester with various aryl bromides leads to alpha-arylated products that can easily be hydrolyzed, giving the corresponding N-protected benzyl phenyl sulfoximines. In this manner, new sulfoximine derivatives are accessible that have so far been difficult to prepare in enantiopure form.
Cho
Gae Young
GY
Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52056 Aachen, Germany.
Bolm
Carsten
C