title: Transhepatic fibrinolysis of mesenteric and portal vein thrombosis in a patient with ulcerative colitis: a case report.
abstract: OBJECTIVE
  To present a case of acute mesenteric and portal vein thrombosis treated with thrombolytic therapy in a patient with ulcerative colitis in acute phase and to review the literature on thrombolytic therapy of mesenteric-portal system. Treatment of acute portal vein thrombosis has ranged from conservative treatment with thrombolysis and anticoagulation therapy to surgical treatment with thrombectomy and/or intestinal resection.
  
  
  METHODS
  We treated our patient with intraportal infusion of plasminogen activator and then heparin through a percutaneous transhepatic catheter.
  
  
  RESULTS
  Thrombus resolved despite premature interruption of the thrombolytic treatment for neurological complications, which subsequently resolved.
  
  
  CONCLUSIONS
  Conservative management with plasminogen activator, could be considered as a good treatment for patients with acute porto-mesenteric thrombosis.
authors.affiliation: First Department of General Surgery, University of verona, Borgo Trento Hospital, P.le Stefani 1, 37126 Verona, Italy. alfredo.guglielmi@univr.it
authors.forename: Alfredo
authors.initials: A
authors.lastname: Guglielmi
authors.forename: Francesca
authors.initials: F
authors.lastname: Fior
authors.forename: Orsolya
authors.initials: O
authors.lastname: Halmos
authors.forename: Gian Franco
authors.initials: GF
authors.lastname: Veraldi
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Rossaro
authors.forename: Andrea
authors.initials: A
authors.lastname: Ruzzenente
authors.forename: Claudio
authors.initials: C
authors.lastname: Cordiano
mesh_terms: D000208:Acute Disease; D000328:Adult; D003093:Colitis, Ulcerative / Q000150:complications*; D005260:Female; D005342:Fibrinolysis; D006801:Humans; D008642:Mesenteric Veins; D010960:Plasminogen Activators / Q000627:therapeutic use; D011169:Portal Vein; D020246:Venous Thrombosis / Q000097:blood* / Q000150:complications* / Q000188:drug therapy
chemical_list: D010960:Plasminogen Activators