title: Handedness shift as a consequence of motor cortex reorganization after early functional impairment in left temporal lobe epilepsy--an fMRI case report.
abstract: The impact of epileptiform activity on the functional organization of various cortical regions is currently a widely discussed topic. Our patient, suffering from left-sided temporal lobe epilepsy with typical mesiotemporal sclerosis, had a remarkable history of a clear-cut handedness shift in early childhood. In this study, we considered the possibility of the functional reorganization of the motor cortex using functional MRI. The results reflect epileptiform activity as an important formative factor for motor cortex development in our patient.
authors.affiliation: 1st Department of Neurology, Masaryk University, St. Anne's University Hospital, Czech Republic. chlepa@centrum.cz
authors.forename: Pavel
authors.initials: P
authors.lastname: Chlebus
authors.forename: Milan
authors.initials: M
authors.lastname: Brázdil
authors.forename: Petr
authors.initials: P
authors.lastname: Hlustík
authors.forename: Michal
authors.initials: M
authors.lastname: Mikl
authors.forename: Marta
authors.initials: M
authors.lastname: Pazourková
authors.forename: Petr
authors.initials: P
authors.lastname: Krupa
mesh_terms: D000293:Adolescent; D004833:Epilepsy, Temporal Lobe / Q000503:physiopathology* / Q000523:psychology* / Q000601:surgery; D005260:Female; D005385:Fingers / Q000502:physiology; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D009044:Motor Cortex / Q000503:physiopathology*; D019635:Neurosurgical Procedures / Q000009:adverse effects; D014705:Verbal Behavior / Q000502:physiology