title: Highly enantioselective Friedel-Crafts alkylations of pyrroles and indoles with alpha'-hydroxy enones under Cu(II)-simple bis(oxazoline) catalysis.
abstract: Remarkably high and regular enantioselectivities are obtained in Friedel-Crafts alkylation reactions involving alpha'-hydroxy enone templates and Cu(II)-bis(oxazoline) complexes as catalysts. The simple elaboration of adducts provides a route to enantioenriched aldehydes, carboxylic acids, and ketones containing the pyrrole and indole frameworks.
authors.affiliation: Departamento de Química Orgánica I, Facultad de Química, Universidad del País Vasco, Apdo. 1072, 20080 San Sebastián, Spain. qoppanic@sc.ehu.es
authors.forename: Claudio
authors.initials: C
authors.lastname: Palomo
authors.forename: Mikel
authors.initials: M
authors.lastname: Oiarbide
authors.forename: Bharat G
authors.initials: BG
authors.lastname: Kardak
authors.forename: Jesús M
authors.initials: JM
authors.lastname: García
authors.forename: Anthony
authors.initials: A
authors.lastname: Linden