The "Statinth" wonder of the world: a panacea for all illnesses or a bubble about to burst.
After the introduction of statins in the market as effective lipid lowering agents, they were shown to have effects other than lipid lowering. These actions were collectively referred to as 'pleiotropic actions of statins.' Pleiotropism of statins formed the basis for evaluating statins for several indications other than lipid lowering. Evidence both in favour and against is available for several of these indications. The current review attempts to critically summarise the available data for each of these indications.
Shafiq
Nusrat
N
Department of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India. samirmalhotra345@yahoo.com
Malhotra
Samir
S
Pandhi
Promila
P
Grover
Anil
A
D000818:Animals; D000963:Antimetabolites / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D004194:Disease; D006331:Heart Diseases / Q000145:classification / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism
D000963:Antimetabolites