title: Synthesis of pyrazine alcaloids from Botryllus leachi. Diazines 43.
abstract: [reaction: see text] Regioselective metalation of pyrazines and cross-coupling reactions provides an easy access to botryllazines A and B and to an isomer of botryllazine A with good yields from chloropyrazine.
authors.affiliation: IRCOF, Laboratoire de Chimie Organique Fine et Hétérocyclique, UMR 6014, INSA, B.P. 08, 76131 Mont St. Aignan Cedex, France.
authors.forename: Frédéric
authors.initials: F
authors.lastname: Buron
authors.forename: Nelly
authors.initials: N
authors.lastname: Plé
authors.forename: Alain
authors.initials: A
authors.lastname: Turck
authors.forename: Guy
authors.initials: G
authors.lastname: Queguiner
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis*; D000818:Animals; D011719:Pyrazines / Q000138:chemical synthesis* / Q000737:chemistry*; D014561:Urochordata / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D011719:Pyrazines; C500475:botryllazine A; C500474:botryllazine B