title: Bilateral testicular tumors in an infertile man previously treated with follicle-stimulating hormones.
abstract: A 43-year-old infertile man with oligozoospermia and normal serum gonadotropin and cytogenetic findings was treated with follicle-stimulating hormone for 1 year at our institution. Two years later, the patient presented with bilateral palpable testicular tumors. His beta-human chorionic gonadotropin and lactate dehydrogenase levels were elevated. Pathologic examination disclosed a pure seminoma in each testis (pT1N0M0). Adjuvant radiotherapy was administered. The tumors might have been induced by follicle-stimulating hormone treatment. Careful follow-up examination of the testis is necessary in men who have received hormonal treatment for infertility.
authors.affiliation: Department of Urology, Showa University School of Medicine, Tokyo, Japan. fukagai@attglobal.net
authors.forename: Takashi
authors.initials: T
authors.lastname: Fukagai
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Kurosawa
authors.forename: Naoki
authors.initials: N
authors.lastname: Sudo
authors.forename: Takayuki
authors.initials: T
authors.lastname: Aso
authors.forename: So
authors.initials: S
authors.lastname: Sugawara
authors.forename: Michio
authors.initials: M
authors.lastname: Naoe
authors.forename: Hideo
authors.initials: H
authors.lastname: Sakamoto
authors.forename: Hideki
authors.initials: H
authors.lastname: Yoshida
mesh_terms: D000328:Adult; D005640:Follicle Stimulating Hormone / Q000009:adverse effects*; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy*; D008297:Male; D018239:Seminoma / Q000139:chemically induced*; D013736:Testicular Neoplasms / Q000139:chemically induced*
chemical_list: D005640:Follicle Stimulating Hormone