Photodynamic therapy in young patients with choroidal neovascularization following traumatic choroidal rupture.
OBJECTIVE
To assesses the role of photodynamic therapy (PDT) with verteporfin in young patients with choroidal neovascularization (CNV) secondary to traumatic choroidal rupture.


METHODS
Retrospective case series.


METHODS
Of 26 eyes with traumatic choroidal rupture followed since 1984 at the retina service of university hospitals, all eyes diagnosed with CNV and treated with PDT were included. Medical records including comprehensive eye examination, retinal photography, and intravenous fluorescein angiography (IVFA) were studied.


RESULTS
Five patients (mean age, 18 years) developed CNV and received an average of two PDT treatments. Three patients had improved visual acuity (VA), one remained stable, and one experienced visual loss. Final IVFA showed absence of leakage in four eyes and decreased leakage in the eye with decreased VA.


CONCLUSIONS
In young patients, PDT may be a reasonable treatment for CNV secondary to choroidal rupture. No ocular or systemic PDT complications were encountered in this young population.
Harissi-Dagher
Mona
M
Retina Service, Ophthalmology Department, University of Montreal; Hôpital Notre-Dame, Montreal, Quebec, Canada. monadagher@hotmail.com
Sebag
Mikael
M
Gauthier
Danny
D
Marcil
Gilles
G
Labelle
Pierre
P
Arbour
Jean Daniel
JD
D000293:Adolescent; D000328:Adult; D002829:Choroid / Q000293:injuries*; D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005131:Eye Injuries / Q000150:complications*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D011166:Porphyrins / Q000627:therapeutic use*; D012189:Retrospective Studies; D012421:Rupture; D000077362:Verteporfin; D014792:Visual Acuity
D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin