Underuse of controller medications among children with persistent asthma in the Ohio medicaid population: evolving differences with new medications.
BACKGROUND
Despite innovations in asthma care, morbidity and mortality have increased significantly. Underuse of controller medications is a major contributor to increased morbidity and mortality.


OBJECTIVE
To determine the extent of underuse of asthma controller medications among Ohio Medicaid children and to determine if there are racial differences in controller medication claims.


METHODS
We conducted a retrospective analysis of Ohio Medicaid claims data. The source data included all institutional, medical service, and pharmacy claims for fee-for-service patients between January 1, 1997, and December 31, 2001. We identified children with persistent asthma using Health Employer Data Information System criteria. The primary outcome was a controller medication claim. We used multivariable logistic regression to identify risk factors for underutilizing asthma controller medications and applied generalized estimating equations to account for repeated measures.


RESULTS
The proportion of children with claims for a controller medication increased from 53% in 1997 to 67% in 2001. Although there were no racial differences in medication claims in 1997, a smaller proportion of African American children had a claim for a controller medication in 2001 (64.8% vs 67.8%, P < .001). Leukotriene antagonists (LTAs) were driving this difference. Individuals residing in urban areas were significantly less likely to have claims for LTAs when compared with those who resided in nonurban areas.


CONCLUSIONS
Overall use of asthma controller medications among Ohio Medicaid children was poor. There was a widening racial difference in controller medication claims over the 5-year study. Regional differences in LTA claims were driving this racial difference.
Wilson
Stephen E
SE
Division of General Internal Medicine, Department of Internal Medicine, College of Medicine, University of Cincinnati, Ohio, USA. Stephen.Wilson@uc.edu
Leonard
Anthony
A
Moomaw
Charles
C
Schneeweiss
Sebastian
S
Eckman
Mark H
MH
D000293:Adolescent; D001741:Black or African American; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy* / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D020024:Leukotriene Antagonists / Q000627:therapeutic use*; D008297:Male; D008484:Medicaid; D009820:Ohio / Q000453:epidemiology
D018927:Anti-Asthmatic Agents; D020024:Leukotriene Antagonists