Differentiation of perianal fistulas with digital subtraction magnetic resonance fistulography.
BACKGROUND
Pelvic magnetic resonance imaging (MRI) is accurate in identifying perianal fistulas. The exact visualization of fistulous tracts and concomitant abscesses determine the type of treatment. To improve the detection of perianal fistulas, we studied digital subtraction MR-fistulography for tissue differentiation based on signal intensity measurements.


METHODS
This study included 75 patients with the clinical diagnosis of perianal fistula. All patients were analyzed by a thin-slice, high-resolution, fast low-angle shot 3-dimensional sequence in the axial plane before and after intravenous injection of gadobenate dimeglumine, followed by image subtraction. Operator-defined regions of interest were used to calculate signal intensities of the inflamed fibrous walls of fistulas, the common femoral artery, the internal and external sphincter muscles, and the gluteus muscle. The fistulas were classified according to Parks classification.


RESULTS
Based on signal intensity measurements in 75 patients with perianal fistulas, diagnosed by digital subtraction MR-fistulography, a significant differentiation between fistulous tracts and anatomic structures was possible. MRI identified 116 perianal fistulas (34 intersphincteric, 33 transsphincteric, 10 suprasphincteric, and 39 extrasphincteric) and 35 abscesses.


CONCLUSIONS
Digital subtraction MR-fistulography is a new, promising, noninvasive imaging technique for the detection of perianal fistulas and abscesses.
Schaefer
Oliver
O
Department of Radiology, University Hospital of Freiburg, Freiburg, Germany. schaefer@mrs1@ukl.uni-freiburg.de
Lohrmann
Christian
C
Kreisel
Wolfgang
W
Rasenack
Jens
J
Ruf
Guenther
G
Hopt
Ulrich
U
Langer
Mathias
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001003:Anal Canal / Q000473:pathology; D002081:Buttocks / Q000473:pathology; D002648:Child; D003287:Contrast Media; D005260:Female; D005263:Femoral Artery / Q000473:pathology; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008536:Meglumine / Q000031:analogs & derivatives*; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology; D009942:Organometallic Compounds; D012003:Rectal Fistula / Q000473:pathology*; D013382:Subtraction Technique
D003287:Contrast Media; D009942:Organometallic Compounds; C064572:gadobenic acid; D008536:Meglumine