title: [Anesthetic management of an 18-trisomy neonate with high frequency ventilation].
abstract: Neonates with 18-trisomy syndrome have various anomalies including cardiac and facial anomalies. Active treatments for them have not been recommended due to a low survival over one year which is less than 10%. However, the survival over one year in our institute between 1985 and 2003 is higher at 22%, and we had a patient with survival of over 5 years. We report a case of anesthetic management in a male 18-trisomy neonate who received a radical repair of umbilical hernia immediately after his birth. Tracheal intubation was difficult due to small airway and facial anomalies; cleft clip, cleft palate, and macrognathia. Conventional ventilation was ineffective for elimination of carbon dioxide and oxygenation due to pulmonary hypoplasia and intra- and extra-cardiac shunts. A high frequency ventilation improved elimination of carbon dioxide and oxygenation.
authors.affiliation: Department of Anesthesiology, Kansai Medical University Hospital, Moriguchi.
authors.forename: Michiyo
authors.initials: M
authors.lastname: Kimoto
authors.forename: Kohei
authors.initials: K
authors.lastname: Murao
authors.forename: Makiko
authors.initials: M
authors.lastname: Yamada
authors.forename: Masayuki
authors.initials: M
authors.lastname: Teraguchi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Ohashi
authors.forename: Akiko
authors.initials: A
authors.lastname: Takeyasu
authors.forename: Shinichi
authors.initials: S
authors.lastname: Nakao
authors.forename: Koh
authors.initials: K
authors.lastname: Shingu
mesh_terms: D000015:Abnormalities, Multiple; D000758:Anesthesia / Q000379:methods*; D002887:Chromosomes, Human, Pair 18; D005145:Face / Q000002:abnormalities; D006352:Heart Ventricles / Q000002:abnormalities; D006554:Hernia, Umbilical / Q000601:surgery*; D006612:High-Frequency Ventilation; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011667:Pulmonary Veins / Q000002:abnormalities; D014314:Trisomy