Sino-nasal epithelial tumours: a pathological study of 69 cases.
BACKGROUND
Epithelial neoplasms are uncommon lesions affecting the sino-nasal tract. There are hardly any reports in the Indian literature.


OBJECTIVE
To study the incidence, mode of presentation and histological types of sino-nasal epithelial tumours in the surgical pathology material.


METHODS
Retrospective retrieval of all sino-nasal tumours and analysis of epithelial tumours.


METHODS
All sino-nasal epithelial tumours, biopsied or surgically excised over a period of ten years, were studied. The tumours were classified as benign or malignant. The histology was correlated with the clinical presentation and investigations.


RESULTS
In ten years, there were 120 sino-nasal tumours representing 0.14% of all the surgical specimens received. Sixty-nine epithelial tumours (59.2%) outnumbered the non-epithelial tumours and were diagnosed on the basis of histopathology. Twenty were benign and 49 malignant; occurring predominantly in males. Benign lesions included four squamous papillomas and 16 inverted papillomas, with recurrence in three inverted papillomas (21%). Squamous cell carcinomas were the commonest among malignant tumours and four of these were associated with inverted or cylindrical cell papilloma. The second most frequent malignant tumour was adenoid cystic carcinoma with eight cases. Other rare types included the variants of squamous carcinoma, adenocarcinomas of the non-enteric type, muco-epidermoid carcinoma and undifferentiated carcinomas.


CONCLUSIONS
Sino-nasal epithelial tumours are rare lesions, with male preponderance. Inverted papillomas and squamous cell carcinomas are the most frequent neoplasms.
Panchal
L
L
Department of Pathology, Seth G. S. Medical College, Parel, Mumbai-400 012, India.
Vaideeswar
P
P
Kathpal
D
D
Madiwale
C V
CV
Prabhat
D P
DP
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010212:Papilloma / Q000473:pathology*; D010255:Paranasal Sinus Neoplasms / Q000473:pathology*; D012189:Retrospective Studies