[Nephrogenic rests and nephroblastomatosis].
The term nephrogenic rests has been proposed for abnormally persistant foci of embryonal cells within developmentally normal kidneys. The term nephroblastomatosis is defined as the presence of diffuse or multiple nephrogenic rests. Nephrogenic rests represent precursors of nephroblatoma and they are associated with certain syndromes carrying a high risk for nephroblastoma. In his classification, Beckwith describes different types of nephrogenic rests according to topographic and morphological features. The nephrogenic rests may undergo regression or proliferation with a high risk for development of a nephroblatoma.
Perlman
Elisabeth
E
Department of Pathology, Children's Memorial Hospital, Annex Bldg, Room A204, 2373 N. Lincold Avenue, Chicago, IL 60614, USA.
Dijoud
Frédérique
F
Boccon-Gibod
Lilianne
L
D003937:Diagnosis, Differential; D006801:Humans; D007668:Kidney / Q000002:abnormalities / Q000196:embryology* / Q000473:pathology; D007680:Kidney Neoplasms / Q000473:pathology*; D011230:Precancerous Conditions / Q000473:pathology; D009396:Wilms Tumor / Q000473:pathology* / Q000628:therapy