title: Detection of combined hepatocellular and cholangiocarcinomas on enhanced CT: comparison with histologic findings.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the performance of enhanced CT in making a diagnosis of combined hepatocellular and cholangiocarcinomas (HCC-CCs) by comparing CT findings with histologic findings.
  
  
  CONCLUSIONS
  One third (nine of 27 cases) of the combined HCC-CCs were correctly diagnosed on enhanced CT by detailed analysis of the enhancing pattern around or within the mass. Various factors such as an atypical enhancing pattern, the size of each component, and the presence of a mass composed of intermediate tumor cells-that is, cells with intermediate characteristics between HCC and CC-were found to be the causes of misdiagnosis of combined HCC-CC on enhanced CT.
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku Fukuoka 812-8582, Japan. anishie@radiol.med.kyushuu.ac.jp
authors.forename: Akihiro
authors.initials: A
authors.lastname: Nishie
authors.forename: Kengo
authors.initials: K
authors.lastname: Yoshimitsu
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Asayama
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Irie
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Aibe
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Tajima
authors.forename: Kenji
authors.initials: K
authors.lastname: Shinozaki
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Nakayama
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kakihara
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Shimada
authors.forename: Shin-Ichi
authors.initials: S
authors.lastname: Aishima
authors.forename: Kisaku
authors.initials: K
authors.lastname: Yoshida
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Honda
mesh_terms: D000328:Adult; D000368:Aged; D001650:Bile Duct Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D001653:Bile Ducts, Intrahepatic / Q000000981:diagnostic imaging* / Q000473:pathology; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging* / Q000473:pathology; D018281:Cholangiocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D003287:Contrast Media; D005260:Female; D006801:Humans; D007479:Iopamidol; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D007479:Iopamidol