title: Life-threatening airway obstruction caused by mediastinal germinoma in a 9-year-old girl.
abstract: The authors report a case of a 9-year-old girl with a mediastinal germinoma that required emergent surgical extirpation because of tracheal compression and asphyxia. The tumor was successfully debulked under general anesthesia with the capability of extracorporeal circulation immediately available. Postoperatively, the tumor responded to adjuvant chemotherapy and irradiation and the patient survived without evidence of recurrence.
authors.affiliation: Department of Surgery, National Center for Child Health and Development, Tokyo 157-8535, Japan. morikawa-n@ncchd.go.jp
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Morikawa
authors.forename: Toshiro
authors.initials: T
authors.lastname: Honna
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Kuroda
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Tanaka
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Kitano
authors.forename: Miwako
authors.initials: M
authors.lastname: Nakano
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Matsuda
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Tanaka
authors.forename: Noriko
authors.initials: N
authors.lastname: Kawashima
authors.forename: Jun
authors.initials: J
authors.lastname: Miyauchi
mesh_terms: D000402:Airway Obstruction / Q000209:etiology*; D000768:Anesthesia, General; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D001237:Asphyxia / Q000209:etiology; D001249:Asthma / Q000175:diagnosis; D001761:Bleomycin / Q000008:administration & dosage; D016190:Carboplatin / Q000008:administration & dosage; D017024:Chemotherapy, Adjuvant; D002648:Child; D003131:Combined Modality Therapy; D000075202:Contraindications; D003951:Diagnostic Errors; D004417:Dyspnea / Q000209:etiology; D004630:Emergencies; D004829:Epilepsy, Generalized / Q000209:etiology; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D018237:Germinoma / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D000860:Hypoxia / Q000209:etiology; D008479:Mediastinal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D012074:Remission Induction; D014057:Tomography, X-Ray Computed; D014135:Tracheal Stenosis / Q000209:etiology*
chemical_list: D001761:Bleomycin; D005047:Etoposide; D016190:Carboplatin