Update on risk factors for atherosclerosis: the role of inflammation and apolipoprotein E.
Over 1 million adults will have a new or recurrent myocardial infarction this year. Traditional risk factor assessment predicts less than one-half of all future cardiovascular events, and many patients develop atherosclerosis in the absence of these factors. Alternative risk factors, including genotype and the inflammatory response, are presented, along with intervention considerations for the medical-surgical nurse.
Foley
Susan M
SM
School of Nursing, Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA.
D001057:Apolipoproteins E / Q000737:chemistry / Q000145:classification / Q000235:genetics* / Q000378:metabolism; D001161:Arteriosclerosis / Q000453:epidemiology / Q000209:etiology* / Q000378:metabolism / Q000517:prevention & control; D002792:Cholestyramine Resin / Q000627:therapeutic use; D018752:Diet, Fat-Restricted; D015444:Exercise; D005838:Genotype; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006949:Hyperlipidemias / Q000150:complications; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D007249:Inflammation; D007388:Internal Medicine; D008019:Life Style; D008074:Lipoproteins / Q000378:metabolism; D009525:Niacin / Q000627:therapeutic use; D024802:Nurse's Role; D009730:Nursing Assessment; D013527:Perioperative Nursing / Q000458:organization & administration; D018570:Risk Assessment; D012307:Risk Factors; D013041:Specialties, Nursing / Q000458:organization & administration; D017539:Tunica Intima / Q000276:immunology / Q000378:metabolism / Q000473:pathology
D001057:Apolipoproteins E; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D000960:Hypolipidemic Agents; D008074:Lipoproteins; D002792:Cholestyramine Resin; D009525:Niacin