title: Diagnosis of coronary artery disease with dobutamine-stress MRI.
abstract: Dobutamine-stress cardiovascular magnetic resonance (CMR) is a new diagnostic tool for the non-invasive detection of coronary artery disease. Technological advances in CMR have evolved this technique to an adequate alternative to the standard cardiac stress tests. Its high reproducibility and excellent image quality of the anatomical features of the left ventricle and left ventricular function at rest and during stress make it an ideal technique for the comprehensive evaluation of patients with suspected coronary artery disease. Besides its ability to detect myocardial ischemia, CMR has proved to be diagnostic for myocardial viability as well. A recent technical refinement in CMR using myocardial tagging has improved the diagnostic accuracy for myocardial ischemia even further. Dobutamine-stress CMR is used to identify wall motion abnormalities of the left ventricle in patients with proven or suspected coronary artery disease [1-4]. Dobutamine-stress CMR has emerged as a highly accurate and safe diagnostic modality [1-4]. Recently, the use of high-dose dobutamine CMR in combination with the myocardial tagging technique has been reported, with excellent diagnostic results. The use of this new technique and the clinical applications are discussed.
authors.affiliation: Department of Radiology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. kps@xs4all.nl
authors.forename: Dirkjan
authors.initials: D
authors.lastname: Kuijpers
mesh_terms: D000318:Adrenergic beta-Agonists; D003327:Coronary Disease / Q000175:diagnosis*; D004280:Dobutamine; D005080:Exercise Test / Q000379:methods*; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods; D017202:Myocardial Ischemia / Q000175:diagnosis; D009206:Myocardium / Q000473:pathology; D015203:Reproducibility of Results; D014022:Tissue Survival; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis; D016277:Ventricular Function, Left / Q000502:physiology
chemical_list: D000318:Adrenergic beta-Agonists; D004280:Dobutamine