title: Takotsubo (ampulla-shaped) cardiomyopathy associated with microscopic polyangiitis.
abstract: Recently, a cardiac disorder characterized by ballooning and hypokinesis at the apex has been described as takotsubo (ampulla-shaped) cardiomyopathy. We encountered a patient with a rare case of takotsubo cardiomyopathy associated with microscopic polyangiitis. A 70-year-old woman suddenly presented with ventricular dysfunction during the active phase of microscopic polyangiitis. The findings on echocardiograms and electrocardiograms were consistent with those of takotsubo cardiomyopathy. The ventricular dysfunction completely resolved after treatment with 40 mg/day of prednisolone and methylprednisolone pulse therapy. This unique type of cardiomyopathy can be a complication of microscopic polyangiitis.
authors.affiliation: Department of Allergy and Rheumatology, Japanese Red Cross Medical Center Hospital, Shibuya-ku, Tokyo 150-8935.
authors.forename: Takeo
authors.initials: T
authors.lastname: Sato
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Hagiwara
authors.forename: Aya
authors.initials: A
authors.lastname: Nishikido
authors.forename: Shingo
authors.initials: S
authors.lastname: Miyamoto
authors.forename: Kota
authors.initials: K
authors.lastname: Komiyama
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Matsuno
authors.forename: Hideji
authors.initials: H
authors.lastname: Hashida
authors.forename: Naoshi
authors.initials: N
authors.lastname: Kobayakawa
authors.forename: Osamu
authors.initials: O
authors.lastname: Akiyama
mesh_terms: D000368:Aged; D001167:Arteritis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D001706:Biopsy; D009202:Cardiomyopathies / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D003331:Coronary Vessels / Q000473:pathology; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use; D009206:Myocardium / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone; D008775:Methylprednisolone