Polycystic ovary syndrome in post-menopausal women--marker of the metabolic syndrome.
OBJECTIVE
To determine among post-menopausal women, the prevalence of polycystic ovary syndrome (PCOS) and to evaluate the endocrine and metabolic profile of these women in comparisons to women without PCOS.


METHODS
All women attending two post-menopausal outpatient clinics, fulfilling the inclusion criteria, were evaluated by physical examination, detailed questionnaire and laboratory measurements of glucose, lipids and sex-hormone levels.


RESULTS
Among 104 women 7 (6.7%) were diagnosed with PCOS. As compared to women without PCOS, central obesity was more common in the PCOS group (p=0.004), 4/7 had type 2 diabetes compared to 8/97 in the non-PCOS group (p=0.003) and 6/7 versus 31/97 had the characteristic dyslipidemia of the metabolic syndrome (p=0.047).


CONCLUSIONS
PCOS is common in post-menopausal women attending outpatient's clinics, and is a marker for a metabolic profile that is associated with a high-risk for cardiovascular diseases (CVD).
Margolin
Elena
E
Department of Medicine, Kaplan Medical Center, Rehovot, Israel.
Zhornitzki
Taiba
T
Kopernik
Gideon
G
Kogan
Sofy
S
Schattner
Ami
A
Knobler
Hilla
H
D015415:Biomarkers; D005260:Female; D006801:Humans; D007557:Israel / Q000453:epidemiology; D008659:Metabolic Diseases / Q000150:complications*; D008875:Middle Aged; D011085:Polycystic Ovary Syndrome / Q000150:complications / Q000453:epidemiology*; D017698:Postmenopause; D015995:Prevalence
D015415:Biomarkers