Coronary aneurysm after implantation of a paclitaxel-eluting stent.
Formation of coronary aneurysm is a rare complication of stenting with bare metal stents, but based on experimental studies drug-eluting stents may induce toxic effects on the vessel wall with incomplete stent apposition, aneurysm formation and with the potential of stent thrombosis or vessel rupture. We present a 43-year-old man who developed a coronary aneurysm in the right coronary artery 6 months after receiving a paclitaxel-eluting stent. The patient was asymptomatic and the aneurysm was detected in a routine control. Angiography and intracoronary ultrasound demonstrated lack of contact between stent and vessel wall in a 15-mm long segment with maximal aneurysm diameter of 6.0 mm. The patient was successfully treated with a graft stent.
Vik-Mo
Harald
H
Department of Cardiology, St Olav University Hospital, Norwegian University of Science and Technology, Trondheim, Norway. harald.vik-mo@medisin.ntnu.no
Wiseth
Rune
R
Hegbom
Knut
K
D000328:Adult; D015906:Angioplasty, Balloon, Coronary; D003323:Coronary Aneurysm / Q000139:chemically induced* / Q000000981:diagnostic imaging; D023903:Coronary Restenosis / Q000517:prevention & control; D016503:Drug Delivery Systems / Q000009:adverse effects*; D006801:Humans; D008297:Male; D017239:Paclitaxel / Q000009:adverse effects* / Q000627:therapeutic use; D011108:Polymers / Q000009:adverse effects; D015607:Stents / Q000009:adverse effects*; D014463:Ultrasonography
D011108:Polymers; D017239:Paclitaxel