title: Adequacy of dialysis in acute renal failure.
abstract: Renal replacement therapy (RRT) is currently the mainstay of management for patients with acute renal failure (ARF). Adequacy of dialysis in the setting of renal failure is defined poorly and encompasses multiple domains of clinical and biochemical outcomes. Multiple operational factors influence the delivery of adequate dialysis. No current standards exist for RRT for ARF; current RRT practices for ARF generally have been extrapolated from end-stage renal disease (ESRD) literature. The heterogeneity of patient population, variation in RRT practices, and differences in outcomes studied have made it difficult to define or study adequate dialysis in ARF or its impact on clinical outcomes.
authors.affiliation: Department of Critical Care Medicine, CRISMA Laboratory (Clinical Research, Investigation, and Systems Modeling of Acute Illness), University of Pittsburgh, Pittsburgh, PA 15261, USA.
authors.forename: Ramesh
authors.initials: R
authors.lastname: Venkataraman
authors.forename: Paul
authors.initials: P
authors.lastname: Palevsky
authors.forename: John A
authors.initials: JA
authors.lastname: Kellum
mesh_terms: D058186:Acute Kidney Injury / Q000628:therapy*; D006801:Humans; D008567:Membranes, Artificial; D006435:Renal Dialysis / Q000379:methods / Q000592:standards*
chemical_list: D008567:Membranes, Artificial