Identification and frequency of a new HLA-A allele, A*030104.
We here identified a novel HLA-A allele, A*030104, which was found in a Japanese family. The direct sequencing revealed that A*030104 was identical to A*030101 except for a nucleotide substitution of GAG to GAA at codon 63 without an amino acid replacement. The frequencies of A*030104 and A*0301 including A*030104 in Japanese population (n = 22,360) were approximately 0.013 and 0.40%, respectively.
Murata
M
M
Department of Hematology, Nagoya University Graduate School of Medicine, Nagoya, Japan. mmurata@med.nagoya-u.ac.jp
Emi
N
N
Izumisawa
Y
Y
Inaki
A
A
Saitoh
M
M
Naoe
T
T
D000483:Alleles; D001483:Base Sequence; D005787:Gene Frequency; D015234:HLA-A Antigens / Q000235:genetics*; D015791:HLA-A3 Antigen; D006801:Humans; D008969:Molecular Sequence Data
D015234:HLA-A Antigens; C442141:HLA-A*03:01 antigen; D015791:HLA-A3 Antigen