title: [Relationship between invasive pituitary adenomas and cavernus sinus and cariod artery and surgical outcomes].
abstract: OBJECTIVE
  To analyze the relationship between invasive pituitary adenomas and cavernus sinus and cariod artery and to predict their surgical outcomes.
  
  
  METHODS
  Totally 270 patients with pituitary tumors were investigated in this retrospective study, including 113 men and 157 women, with a mean age of 40.8 years. The mean disease history was 3.6 years. Pituitary microadenomas were diagnosed in 56 cases, macroadenomas in 118 cases, and hugeadenomas in 96 cases. Adrenocorticotropic hormone-releasing adenomas (Cushing's diseases) were diagnosed in 40 cases, growth hormone-releasing adenomas in 58 cases, prolactinomas in 57 cases, and non-functional pituitary adenomas in 115 cases. Transsphenoidal microsurgery were performed on 260 patients, while transcranial microsurgery on 6 patients.
  
  
  RESULTS
  The percentage of invasive pituitary adenomas was about 3.6% in microadenomas, 20.4% in macroadenomas, and 61.4% in hugeadenomas. Rate of total removal was 94.1% in non-invasive pituitary adenomas, and was 58.8% in invasive pituitary adenomas.
  
  
  CONCLUSIONS
  It is important to analyze the grade of invasive pituitary adenomas to improve the removal of pituitary adenomas, avoid injuring cariod artery, and increase the rate of total removal.
authors.affiliation: Department of Neurosurgery, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
authors.forename: Zu-yuan
authors.initials: ZY
authors.lastname: Ren
authors.forename: Yi
authors.initials: Y
authors.lastname: Yang
authors.forename: Chang-bao
authors.initials: CB
authors.lastname: Su
authors.forename: Ren-zhi
authors.initials: RZ
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Tao
authors.forename: Wen-bin
authors.initials: WB
authors.lastname: Ma
authors.forename: Yong-ning
authors.initials: YN
authors.lastname: Li
mesh_terms: D000236:Adenoma / Q000473:pathology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002339:Carotid Arteries / Q000473:pathology* / Q000601:surgery; D002426:Cavernous Sinus / Q000473:pathology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007016:Hypophysectomy / Q000379:methods; D008279:Magnetic Resonance Imaging; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D047748:Pituitary ACTH Hypersecretion / Q000473:pathology / Q000601:surgery*; D010911:Pituitary Neoplasms / Q000473:pathology / Q000601:surgery*; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D016896:Treatment Outcome