Molecular diversity of Artocarpus champeden (Moraceae): a species endemic to Indonesia.
A summary of results obtained in the study of natural products isolated from a Moraceae species Artocarpus champeden is presented. The various classes of 3-prenylflavonoids isolated and the biogenetical correlation between the metabolites are discussed. Some of the flavonoids exhibited strong cytotoxicity against murine leukemia P388 cell lines, suggesting that flavonoids derived from moraceous plants represent a plausible unexplored resource of novel antitumor leads.
Hakim
Euis H
EH
Natural Products Research Group, Department of Chemistry, Institut Teknologi Bandung, Jalan Ganeca 10, Bandung 40132, Indonesia.
Juliawaty
Lia D
LD
Syah
Yana M
YM
Achmad
Sjamsul A
SA
D000818:Animals; D031622:Artocarpus / Q000737:chemistry / Q000145:classification* / Q000235:genetics*; D001685:Biological Factors / Q000302:isolation & purification / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D045744:Cell Line, Tumor; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007214:Indonesia; D007941:Leukemia P388; D051379:Mice; D008517:Phytotherapy
D001685:Biological Factors; D005419:Flavonoids