Fibers connecting the primary motor and sensory areas play a role in grasp stability of the hand.
The goal of this study was to evaluate the function of fibers that connect the hand area of the primary motor and sensory cortices. A 63-year-old male with a metastatic brain tumor located in the left primary motor area underwent awake surgery. During removal of the tumor, the posterior end of the primary motor cortex, including the fibers between the motor and sensory cortex, was resected, as confirmed by 3D reconstruction of fMRI and diffusion tensor imaging (DTI). Preoperative fMRI with right hand clenching revealed activation in the area around the tumor in the primary motor area. Postoperative fMRI with right hand clenching showed posterior shift of the activation to the sensory area. In contrast, 3D reconstruction of fMRI and DTI with left hand clenching showed activation of cortex corresponding to the motor and sensory hand area. Postoperative neurological examination revealed no change in right hand strength, but the patient complained of decrease right hand grasp stability when he concentrated on using his left hand. These findings suggest that the fibers connecting the primary hand motor and sensory areas play a role in the hand grasp stability.
Shinoura
Nobusada
N
Department of Neurosurgery, Komagome Metropolitan Hospital, 3-18-22 Hon-Komagome, Bunkyo-ku, Tokyo 113-8677, Japan. shinoura@cick.jp
Suzuki
Yuich
Y
Yamada
Ryozi
R
Kodama
Takashi
T
Takahashi
Masamichi
M
Yagi
Kazuo
K
D001932:Brain Neoplasms / Q000503:physiopathology / Q000556:secondary / Q000601:surgery; D038524:Diffusion Magnetic Resonance Imaging; D004292:Dominance, Cerebral / Q000502:physiology; D005500:Follow-Up Studies; D007839:Functional Laterality / Q000502:physiology*; D006225:Hand / Q000294:innervation; D018737:Hand Strength / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008175:Lung Neoplasms / Q000503:physiopathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009044:Motor Cortex / Q000503:physiopathology* / Q000601:surgery; D009048:Motor Skills / Q000502:physiology; D009412:Nerve Fibers / Q000502:physiology*; D009415:Nerve Net / Q000503:physiopathology* / Q000601:surgery; D019150:Neuroaxonal Dystrophies; D009460:Neurologic Examination; D011183:Postoperative Complications / Q000175:diagnosis / Q000503:physiopathology; D013003:Somatosensory Cortex / Q000503:physiopathology* / Q000601:surgery