Pharmacological treatments of pathological gambling.
Medication treatment studies have demonstrated short-term efficacy of various SRIs, opioid antagonists, and mood stabilizers in sub-samples of adult treatment seeking pathological gamblers. Pathological gambling is frequently comorbid with bipolar spectrum disorders, substance abuse/dependence, and attention-deficit/hyperactivity disorder (ADHD), and comorbidity may influence treatment response in pathological gambling. This review focuses on recent research examining the treatment of pathological gambling and highlights methodological challenges for future studies.
Hollander
Eric
E
Department of Psychiatry, Compulsive, Impulsive and Anxiety Disorders Program, Mount Sinai School of Medicine, Box 1230, One Gustave L. Levy Place, New York, NY, USA. eric.Hollander@mssm.edu
Sood
Erica
E
Pallanti
Stefano
S
Baldini-Rossi
Nicolo
N
Baker
Bryann
B
D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use*; D016739:Behavior, Addictive / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D016642:Bupropion / Q000627:therapeutic use; D015897:Comorbidity; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D016666:Fluvoxamine / Q000627:therapeutic use; D005715:Gambling / Q000523:psychology; D006801:Humans; D009271:Naltrexone / Q000627:therapeutic use; D017063:Outcome Assessment, Health Care; D017374:Paroxetine / Q000627:therapeutic use; D010879:Piperazines; D012107:Research Design; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D019966:Substance-Related Disorders / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D014230:Triazoles / Q000627:therapeutic use
D018687:Antidepressive Agents, Second-Generation; D016642:Bupropion; D016666:Fluvoxamine; D009271:Naltrexone; D017374:Paroxetine; D010879:Piperazines; D017367:Selective Serotonin Reuptake Inhibitors; D014230:Triazoles; C051752:nefazodone