title: Effects of bacterial adhesion with respect to the type of material, structure and design of intraocular lenses.
abstract: The properties of the biomaterials used to constitute lenses are important factors choosing a lens for human implantation because these can influence in posterior clinical evolutions of patients. In this study, different characteristics of intraocular lenses such as chemical composition, surface roughness and lens design have been investigated in terms of their influence into a pathological environment. Eight commercial lenses were tested by optical profiling, Infrared spectra with Fourier transformation (FTIR), water-material contact angle and scanning electron microscope (SEM) to know their chemical composition and structural characteristics. These lenses were then exposed to infectious conditions in order to evaluate their responses to the bacterial environment.
authors.affiliation: INASMET Foundation, Materials Research Centre, Spain.
authors.forename: J I
authors.initials: JI
authors.lastname: Alava
authors.forename: N
authors.initials: N
authors.lastname: Garagorri
authors.forename: N
authors.initials: N
authors.lastname: Briz
authors.forename: J
authors.initials: J
authors.lastname: Mendicute
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry; D001422:Bacterial Adhesion / Q000502:physiology*; D001672:Biocompatible Materials / Q000737:chemistry; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D007910:Lenses, Intraocular; D008855:Microscopy, Electron, Scanning; D011102:Polyhydroxyethyl Methacrylate / Q000737:chemistry; D011109:Polymethacrylic Acids / Q000737:chemistry; D019904:Polymethyl Methacrylate / Q000737:chemistry; D011145:Polyvinyls / Q000737:chemistry; D011474:Prosthesis Design; D011550:Pseudomonas aeruginosa / Q000502:physiology; D012828:Silicones / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D005465:Fluorocarbon Polymers
chemical_list: D000180:Acrylic Resins; D001672:Biocompatible Materials; D004129:Dimethylpolysiloxanes; D011102:Polyhydroxyethyl Methacrylate; D011109:Polymethacrylic Acids; D019904:Polymethyl Methacrylate; D011145:Polyvinyls; D012828:Silicones; C478961:poly(ethylacrylate); C098156:polybenzylmethacrylate; C024865:polyvinylidene fluoride; D005465:Fluorocarbon Polymers; C013830:baysilon