title: Clinicopathological survey of 101 canine mammary gland tumors: differences between small-breed dogs and others.
abstract: Clinicopathological features of mammary gland tumors (MGTs) in 101 dogs were evaluated retrospectively. The incidence of histological malignancy in 60 small- and 41 other-breed dogs were 25% and 58.5%, respectively. In 82 epithelial MGTs, small-sized tumors (< 3 cm) or non-invasive tumors were predominant in small breeds. In multivariate survival analysis, small breed (p=0.048) and lower stage of tumor cell invasion (p=0.006) were significantly associated with longer survival time. These results suggest that the incidence of histological or biological malignancy in MGTs is lower in small-breed dogs than in others.
authors.affiliation: Division of Animal Medical Research, Miyazaki 881-0012, Japan.
authors.forename: Teruo
authors.initials: T
authors.lastname: Itoh
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Uchida
authors.forename: Kenichi
authors.initials: K
authors.lastname: Ishikawa
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Kushima
authors.forename: Eiko
authors.initials: E
authors.lastname: Kushima
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Tamada
authors.forename: Takashi
authors.initials: T
authors.lastname: Moritake
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakao
authors.forename: Hiroki
authors.initials: H
authors.lastname: Shii
mesh_terms: D000818:Animals; D049628:Body Size; D004283:Dog Diseases / Q000401:mortality* / Q000473:pathology; D004285:Dogs; D007564:Japan; D015674:Mammary Neoplasms, Animal / Q000401:mortality* / Q000473:pathology; D012189:Retrospective Studies; D013045:Species Specificity; D016019:Survival Analysis