Antimutagenic and antioxidant properties of milk-kefir and soymilk-kefir.
This study was aimed at evaluating the antimutagenic and antioxidant properties of milk-kefir and soymilk-kefir. Such antimutagenic activity was determined by means of the Salmonella mutagenicity assay, whereas the antioxidant properties of kefir were evaluated by assessing the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity, lipid peroxidation inhibition activity, ferrous ion chelating ability, reducing power, and antioxidative enzyme activity. Both milk-kefir and soymilk-kefir demonstrated significantly greater antimutagenic activity than milk and soymilk. Milk-kefir and soymilk-kefir also displayed significantly greater scavenging activity upon DPPH radicals, an inhibition effect upon linoleic acid peroxidation, and more substantial reducing power but displayed a reduced glutathione peroxidase activity than was the case for milk and soymilk. Milk and soymilk fermented by kefir grains did not alter the ferrous ion chelating ability and superoxide dismutase activity of the original materials. These findings have demonstrated that milk-kefir and soymilk-kefir possess significant antimutagenic and antioxidant activity and suggest that milk-kefir and soymilk-kefir may be considered among the more promising food components in terms of preventing mutagenic and oxidative damage.
Liu
Je-Ruei
JR
Department of Animal Science, National Taiwan University, Taipei, Taiwan, Republic of China. jerryliu@seed.net.tw
Chen
Ming-Ju
MJ
Lin
Chin-Wen
CW
D000818:Animals; D016587:Antimutagenic Agents / Q000032:analysis* / Q000494:pharmacology; D000975:Antioxidants / Q000032:analysis* / Q000494:pharmacology; D001713:Biphenyl Compounds; D043302:Cultured Milk Products / Q000737:chemistry*; D005285:Fermentation; D005296:Ferrous Compounds / Q000737:chemistry; D007502:Iron Chelating Agents / Q000737:chemistry; D015227:Lipid Peroxidation / Q000187:drug effects; D008892:Milk / Q000737:chemistry*; D009152:Mutagenicity Tests; D010084:Oxidation-Reduction; D010851:Picrates / Q000737:chemistry; D041942:Soy Milk / Q000737:chemistry*
D016587:Antimutagenic Agents; D000975:Antioxidants; D001713:Biphenyl Compounds; D005296:Ferrous Compounds; D007502:Iron Chelating Agents; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl