A simple approach to the synthesis of highly functionalized pyrrole derivatives.
The reaction of dibenzoylacetylene and enaminocarbonyl compounds leads to 3-alkylidene-2,3-dihydro-1H-pyrrol-2-ol derivatives in nearly quantitative yields. The reaction of this heterocyclic system with alcohols in the presence of a catalytic amount of HCl produces highly functionalized pyrroles in good yields.
Yavari
Issa
I
Department of Chemistry, University of Tarbiat Modarres, P.O. Box 14115-175, Tehran, Iran. isayavar@yahoo.com
Anary-Abbasinejad
Mohammad
M
Nasiri
Farough
F
Djahaniani
Hoorieh
H
Alizadeh
Abdolali
A
Bijanzadeh
Hamid R
HR
D000478:Alkylation; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D013055:Spectrophotometry, Infrared
D007202:Indicators and Reagents; D011758:Pyrroles