Catalytic enantioselective conjugate addition of dialkylzinc reagents to N-substituted-2,3-dehydro-4-piperidones.
The first, highly enantioselective, copper/phosphoramidite-catalyzed conjugate addition of dialkylzinc reagents to N-substituted 2,3-dehydro-4-piperidones is described.
Sebesta
Radovan
R
Department of Organic and Molecular Inorganic Chemistry, Stratingh Institute, University of Groningen, Nijenborgh 4, 9747, AG Groningen, The Netherlands.
Pizzuti
Maria Gabriella
MG
Boersma
Arnold J
AJ
Minnaard
Adriaan J
AJ
Feringa
Ben L
BL