Optimal cytoreduction after combined resection and radiofrequency ablation of hepatic metastases from recurrent malignant ovarian tumors.
BACKGROUND
The role of radiofrequency ablation (RFA) in the treatment of hepatic metastases from recurrent ovarian tumors is undefined.


METHODS
Three patients with hepatic lesions from recurrent ovarian cancers underwent a combined partial hepatectomy with radiofrequency ablation (RFA) to achieve optimal tumor cytoreduction. Follow-up radiological studies as well as serial tumor markers are consistent with disease-free survival after 39, 13, and 9 months.


CONCLUSIONS
These results demonstrate the feasibility and safety of RFA for metastatic ovarian lesions to the liver in patients previously deemed as poor or non-surgical candidates, and suggest the potential for improvement in survival over unresected patients or in patients resected with residual disease.
Mateo
Rod
R
Department of Surgery, Keck-USC School of Medicine, 1510 San Pablo Street, HCC 430, Los Angeles, CA 90033, USA. rmateo@surgery.usc.edu
Singh
Gagandeep
G
Jabbour
Nicolas
N
Palmer
Suzanne
S
Genyk
Yuri
Y
Roman
Lynda
L
D000368:Aged; D017115:Catheter Ablation; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery*