title: Acetogenins from Annonaceae: recent progress in isolation, synthesis and mechanisms of action.
abstract: The aim of the present review is to summarise the knowledge about newly isolated acetogenins (ACGs) in the last six years. It will also report the total syntheses that have allowed either the confirmation or the revision of some structures, together with the biological activities and mechanism of action of such interesting natural products. In fact, of the 417 isolated compounds reviewed, over 176 have been added during the period from 1998 to 2004.
authors.affiliation: Laboratoire de Pharmacognosie, associe au CNRS (BIOCIS), Faculte de Pharmacie, Universite Paris-Sud, 92296, Chatenay-Malabry, France. bruno.figadere@cep.u-psud.fr.
authors.forename: Almudena
authors.initials: A
authors.lastname: Bermejo
authors.forename: Bruno
authors.initials: B
authors.lastname: Figadere
authors.forename: Maria-Carmen
authors.initials: MC
authors.lastname: Zafra-Polo
authors.forename: Isabel
authors.initials: I
authors.lastname: Barrachina
authors.forename: Ernesto
authors.initials: E
authors.lastname: Estornell
authors.forename: Diego
authors.initials: D
authors.lastname: Cortes
mesh_terms: D054378:Acetogenins; D029061:Annonaceae / Q000737:chemistry*; D000972:Antineoplastic Agents, Phytogenic / Q000138:chemical synthesis / Q000302:isolation & purification / Q000494:pharmacology; D005233:Fatty Alcohols / Q000138:chemical synthesis / Q000302:isolation & purification / Q000494:pharmacology; D007783:Lactones / Q000138:chemical synthesis / Q000302:isolation & purification / Q000494:pharmacology; D015394:Molecular Structure
chemical_list: D054378:Acetogenins; D000972:Antineoplastic Agents, Phytogenic; D005233:Fatty Alcohols; D007783:Lactones