title: Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones.
abstract: Bifunctional organocatalysts of the thiourea-tert-amine type, carrying two "matched" elements of chirality, effect the alcoholytic dynamic kinetic resolution of a variety of azlactones with up to 95% ee.
authors.affiliation: Institut fur Organische Chemie der Universitat zu Koln, Greinstrasse 4, D-50939, Koln, Germany. berkessel@uni-koeln.de
authors.forename: Albrecht
authors.initials: A
authors.lastname: Berkessel
authors.forename: Santanu
authors.initials: S
authors.lastname: Mukherjee
authors.forename: Felix
authors.initials: F
authors.lastname: Cleemann
authors.forename: Thomas N
authors.initials: TN
authors.lastname: Muller
authors.forename: Johann
authors.initials: J
authors.lastname: Lex
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D007700:Kinetics; D007783:Lactones / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism; D013890:Thiourea / Q000737:chemistry
chemical_list: D007783:Lactones; D013890:Thiourea