Mycophenolate mofetil and skin diseases.
Mycophenolate mofetil (MMF) is an immunosuppressive drug the efficiency of which has been established in renal transplantation. Recent studies suggest that it may also be effective in the treatment of variant skin diseases especially if the skin lesions are triggered by lymphocytes. Studies have shown efficacy in autoimmune bullous dermatoses, atopic dermatitis and psoriasis. However, there are no placebo-controlled trials that support the use of MMF as first line therapy in these skin diseases.
Hartmann
M
M
Department of Dermatology, University of Heidelberg, Heidelberg, Germany. Martin-Hartmann@med.uni-heidelberg.de
Enk
A
A
D003876:Dermatitis, Atopic / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D008178:Lupus Erythematosus, Cutaneous / Q000188:drug therapy; D009173:Mycophenolic Acid / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D011565:Psoriasis / Q000188:drug therapy*; D017511:Pyoderma Gangrenosum / Q000188:drug therapy; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy*
D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid