title: [Combined treatment with reaferon and iodantipirin in patients with chronic viral hepatitides B and C].
abstract: OBJECTIVE
  To examine clinical efficacy of combined therapy with reaferon and iodantipirin in patients with chronic hepatitis B and C of moderate activity.
  
  
  METHODS
  100 patients with confirmed diagnosis of chronic viral hepatitis (CVH) at the stage of replication. All the patients have undergone puncture biopsy of the liver with estimation of index of histological activity Knodell and index of fibrosis Desmeth.
  
  
  RESULTS
  Comparative evaluation was made of clinical efficacy of combined therapy reaferon + iodantipirin and monotherapy with reaferon in 100 patients with moderate activity CHB and C.
  
  
  CONCLUSIONS
  Conventional scheme with reaferon turned out less effective than the above combination therapy.
authors.forename: E I
authors.initials: EI
authors.lastname: Beloborodova
authors.forename: M A
authors.initials: MA
authors.lastname: Vnushinskaia
authors.forename: E V
authors.initials: EV
authors.lastname: Beloborodova
authors.forename: M I
authors.initials: MI
authors.lastname: Rachkovskiĭ
authors.forename: A A
authors.initials: AA
authors.lastname: Shalovaĭ
authors.forename: V A
authors.initials: VA
authors.lastname: Burkovskaia
authors.forename: A S
authors.initials: AS
authors.lastname: Saratikov
authors.forename: D I
authors.initials: DI
authors.lastname: Kuz'menko
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000328:Adult; D001707:Biopsy, Needle; D004359:Drug Therapy, Combination; D005260:Female; D019694:Hepatitis B, Chronic / Q000188:drug therapy* / Q000473:pathology; D019698:Hepatitis C, Chronic / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use*; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D017613:Iodine Compounds / Q000627:therapeutic use*; D008099:Liver / Q000473:pathology; D008297:Male; D047069:Pyrazolones / Q000627:therapeutic use*; D011994:Recombinant Proteins; D012720:Severity of Illness Index
chemical_list: C459160:1-phenyl-2,3-dimethyl-4-iodopyrazolone; D000276:Adjuvants, Immunologic; D007370:Interferon Type I; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D017613:Iodine Compounds; D047069:Pyrazolones; D011994:Recombinant Proteins