[Functional state of the liver in patients with an acute destructive pancreatitis in the early postoperative period].
The efficacy of conventional complex treatment and such, including pentoxyphylline, lipoic acid and the aminoacids mixture, was studied in early postoperative period in 64 patients with an acute destructive pancreatitis. The highest levels of general and direct bilirubins, the aminotransferases activity were established initially in those patients, in whom the polyorgan insufficiency syndrome (PIS) occurred subsequently. More significant normalization of the indexes under the influence of treatment was observed in patients without PIS, in patients with PIS the pharmacological resistance was registered. More favourable course of postoperative period was observed in patients, in whom pentoxyphylline, lipoic acid and the aminoacids mixture were included in complex of treatment.
Zaporozhchenko
B S
BS
Shishlov
V I
VI
D000328:Adult; D000596:Amino Acids / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000503:physiopathology*; D008111:Liver Function Tests; D008297:Male; D009102:Multiple Organ Failure / Q000209:etiology / Q000503:physiopathology* / Q000517:prevention & control; D019283:Pancreatitis, Acute Necrotizing / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D010431:Pentoxifylline / Q000627:therapeutic use; D011184:Postoperative Period; D008063:Thioctic Acid / Q000627:therapeutic use; D016896:Treatment Outcome
D000596:Amino Acids; D008063:Thioctic Acid; D010431:Pentoxifylline