title: L-valyl-L-serine trihydrate.
abstract: The valine side chains in the crystal structure of the title compound [systematic name: 2-(2-ammonio-3-methylbutanamido)-3-hydroxypropanoate trihydrate], C8H16N2O4.3H2O, stack along an a axis of 4.77 A to form hydrophobic columns surrounded by remarkable water/hydroxyl shells. The peptide main chains are connected by hydrogen bonds in two-dimensional layers. The peptide molecules in each layer are related only by translation, and generate a very rare pattern. This is rendered possible through the formation of the shortest C(alpha)-H...O(carboxylate) interaction ever recorded.
authors.affiliation: Department of Chemistry, University of Oslo, PO Box 1033 Blindern, N-0315 Oslo, Norway.
authors.forename: Arne
authors.initials: A
authors.lastname: Johansen
authors.forename: Randi
authors.initials: R
authors.lastname: Midtkandal
authors.forename: Heidi
authors.initials: H
authors.lastname: Roggen
authors.forename: Carl Henrik
authors.initials: CH
authors.lastname: Görbitz
mesh_terms: D018360:Crystallography, X-Ray; D004151:Dipeptides / Q000737:chemistry*; D006860:Hydrogen Bonding; D012694:Serine / Q000737:chemistry*; D014633:Valine / Q000737:chemistry*
chemical_list: D004151:Dipeptides; D012694:Serine; D014633:Valine