title: Third-body wear testing of a highly cross-linked acetabular liner: the effect of large femoral head size in the presence of particulate poly(methyl-methacrylate) debris.
abstract: The hip simulator wear performance of an electron beam cross-linked and subsequently melted ultrahigh molecular weight polyethylene against femoral heads of 28-, 38-, and 46-mm diameter in the presence of poly(methyl-methacrylate) particulate debris was contrasted with that of conventional polyethylene against a 46-mm diameter head. Over 5 million cycles of testing, the average wear rate of the conventional polyethylene liners was 29.3 +/- 3.0 mg per million cycles. All highly cross-linked components exhibited marked reduction in wear, with the highest wear measuring 0.74 +/- 0.85 mg per million cycles. This study, using a clinically relevant third-body material, showed the electron beam cross-linked material to be far more resistant to this third-body wear than conventional ultrahigh molecular weight polyethylene, even when very large diameter femoral heads were used.
authors.affiliation: Orthopaedic Biomechanics and Biomaterials Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
authors.forename: Charles R
authors.initials: CR
authors.lastname: Bragdon
authors.forename: Murali
authors.initials: M
authors.lastname: Jasty
authors.forename: Orhun K
authors.initials: OK
authors.lastname: Muratoglu
authors.forename: William H
authors.initials: WH
authors.lastname: Harris
mesh_terms: D000077:Acetabulum / Q000601:surgery*; D000180:Acrylic Resins; D001696:Biomechanical Phenomena; D020099:Coated Materials, Biocompatible; D003432:Cross-Linking Reagents; D019544:Equipment Failure Analysis; D006622:Hip Prosthesis; D006801:Humans; D008970:Molecular Weight; D010316:Particle Size; D020959:Polyethylene; D019904:Polymethyl Methacrylate; D011474:Prosthesis Design; D013499:Surface Properties
chemical_list: D000180:Acrylic Resins; D020099:Coated Materials, Biocompatible; D003432:Cross-Linking Reagents; C477624:GUR 1050 resin; D020959:Polyethylene; D019904:Polymethyl Methacrylate