title: Evaluation of pulmonary function and quality of life in women with osteoporosis.
abstract: Osteoporotic vertebral fractures generally result in an increased kyphotic angle, which in turn may lead to disturbances in pulmonary function. The objective of the present study was to evaluate pulmonary function and quality of life in a group of osteoporotic patients. Fifteen women with osteoporosis and thoracic vertebral fractures (group 1), 20 women with osteoporosis without vertebral fracture (group 2) and 20 control women (group 3) were submitted to spirometry using a Vitatrace-130 SL spirometer and to an SF-36 quality of life questionnaire. Women with osteoporosis and vertebral fractures showed an increased kyphotic angle (median=60 degrees) and decreased forced vital capacity (group 1 vs. group 2, P =0.020; group 1 vs. group 3, P =0.039) and forced expiratory volume in 1 s (group 1 vs. group 2, P =0.008; group 1 vs. group 3, P =0.014) when compared with women without vertebral fractures or osteoporosis. A negative correlation was observed between thoracic kyphosis and the predicted value of expiratory forced volume in 1 s ( r =-0.713, P =0.003). No differences in the quality of life were detected between the three groups studied. We conclude that women with thoracic vertebral fractures have an increased kyphotic angle and present a decrease in lung volume.
authors.affiliation: Rheumatology Rehabilitation Center/Rheumatology Division, Federal University of São Paulo, Rua Botucatu 740, 04023-900 São Paulo, Brazil.
authors.forename: Império
authors.initials: I
authors.lastname: Lombardi
authors.forename: Leda M
authors.initials: LM
authors.lastname: Oliveira
authors.forename: Anamaria F
authors.initials: AF
authors.lastname: Mayer
authors.forename: José R
authors.initials: JR
authors.lastname: Jardim
authors.forename: Jamil
authors.initials: J
authors.lastname: Natour
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D016022:Case-Control Studies; D005260:Female; D005272:Femur Neck / Q000503:physiopathology; D005541:Forced Expiratory Volume; D006305:Health Status Indicators; D006801:Humans; D007738:Kyphosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology; D008159:Lumbar Vertebrae / Q000503:physiopathology; D008168:Lung / Q000503:physiopathology*; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000150:complications / Q000503:physiopathology* / Q000534:rehabilitation; D011788:Quality of Life; D016103:Spinal Fractures / Q000000981:diagnostic imaging / Q000209:etiology; D013147:Spirometry; D018709:Statistics, Nonparametric; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging; D014797:Vital Capacity