[Fibroblastic-myofibroblastic proliferations of childhood and adolescents].
Fibroblastic-myofibroblastic proliferations of childhood and adolescents form a clinical and morphologic spectrum from benign reactive processes and pseudosarcomas, to fibromatoses, to various types of sarcoma. The diagnosis is challenging because of clinical and morphologic similarities, lack of specific immunohistochemical markers for different types of fibroblastic-myofibroblastic tumors, and limited molecular genetic information. Careful attention to clinical, macroscopic, and histopathologic features permits classification in most cases. This review focuses on the pathologic features of fibroblastic-myofibroblastic tumors with a predilection for children and adolescents.
Coffin
Cheryl
C
Department of Pathology, School of Medicine, Salt Lake City, Utah, USA.
Boccon-Gibod
Liliane
L
D000293:Adolescent; D002455:Cell Division; D002648:Child; D003937:Diagnosis, Differential; D005350:Fibroma / Q000145:classification / Q000473:pathology*; D006801:Humans; D047708:Myofibroma / Q000145:classification / Q000473:pathology*; D018218:Neoplasms, Fibrous Tissue / Q000145:classification / Q000473:pathology*