Influence of phytase added to a vegetarian diet on bone metabolism in pregnant and lactating sows.
The purpose of the study was to find out if the supplementation of phytase to a diet of gestating and lactating sows has any effects on performance and bone parameters of the animals. Forty primiparous gilts were assigned into four groups: group A with phytase [4.2 g total phosphorus (P)/kg (gestation) and 4.5 g total P/kg (lactation)], group B without phytase (with phytase supplementation in diet for rearing) and same P content as group A, group C without phytase and higher P contents [5.0 g total P/kg (gestation) and 5.5 g total P/kg (lactation)] and group D with the same diet as group B (no phytase during the rearing). A 6-phytase was used in this trial (750 FTU/kg diet). The four diets were fed during gestation and lactation. Faeces were collected to determine apparent digestibility of minerals. Blood samples were taken to analyse minerals and bone markers. After weaning the sows were slaughtered and the bones of one hind leg were prepared to measure bone mineral density (BMD) and bone mineral content (BMC) of the tibia. Bone ash and mineral content of the phalanx III were determined. Mean P concentrations in serum decreased during gestation and lactation. But there were no significant differences between the groups. Bone formation marker bone-specific alkaline phosphatase decreased at the beginning of lactation whereas bone resorption marker serum crosslaps increased. The BMD and BMC of the tibia were slightly higher in the groups fed higher concentrations of P and phytase. The ash and mineral contents of the phalanx were the highest for the group fed the highest concentration of P. The apparent digestibility of P increased during gestation mostly in group A (57%--> 69%). In conclusion, high P content and addition of phytase to the diet induced a slightly higher ash content of the bones. It is of high importance, that sows during gestation absorb enough P, to avoid lamenesses and sudden fractures. As not many studies with phytase have been performed during gestation and lactation in sows yet, we can recommend, that phytase as supplement can be used to keep P in the diet at a lower level without negative consequences for bone health.
Liesegang
A
A
Institute of Animal Nutrition, Vetsuisse Faculty University of Zurich, 8057 Zurich, Switzerland. aliese@vetphys.unizh.ch
Loch
L
L
Bürgi
E
E
Risteli
J
J
D010832:6-Phytase / Q000008:administration & dosage*; D000469:Alkaline Phosphatase / Q000378:metabolism; D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D015519:Bone Density / Q000187:drug effects / Q000502:physiology; D001846:Bone Development / Q000502:physiology; D001862:Bone Resorption / Q000378:metabolism; D001842:Bone and Bones / Q000187:drug effects / Q000378:metabolism*; D014676:Diet, Vegetarian; D019587:Dietary Supplements; D005260:Female; D007774:Lactation / Q000378:metabolism*; D009751:Nutritional Requirements; D016226:Phosphorus, Dietary / Q000008:administration & dosage* / Q000097:blood; D011247:Pregnancy; D011897:Random Allocation; D013552:Swine / Q000254:growth & development / Q000378:metabolism / Q000502:physiology*; D015430:Weight Gain
D016226:Phosphorus, Dietary; D000469:Alkaline Phosphatase; D010832:6-Phytase