Tryptamine-derived amides and alkaloids from the seeds of Annona atemoya.
A series of N-fatty acyl tryptamines, including a mixture of N-nonadecanoyltryptamine (1), N-behenoyltryptamine (2), N-lignoceroyltryptamine (3), N-cerotoyltryptamine (4), and N-octacosanoyl tryptamine (5), and a mixture of N-tricosanoyl-4,5-dihydroxytryptamine (6), N-lignoceroyl-4,5-dihydroxytryptamine (7), N-pentacosanoyl-4,5-dihydroxytryptamine (8), and N-heptacosanoyl-4,5-dihydroxytryptamine (9), along with two alkaloids, atemoine (10) and cleistopholine, were isolated from the EtOAc extract of seeds of Annona atemoya. The structures of the new compounds, 1 and 5-10, were determined on the basis of spectral evidence.
Wu
Yang-Chang
YC
Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan, Republic of China. yachwu@kmu.edu.tw
Chang
Fang-Rong
FR
Chen
Chung-Yi
CY
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000577:Amides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D031041:Annona / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012639:Seeds / Q000737:chemistry; D013624:Taiwan; D014363:Tryptamines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
D000470:Alkaloids; D000577:Amides; D014363:Tryptamines