Constituents of holothuroidea, 14. Isolation and structure of new glucocerebroside molecular species from the sea cucumber Stichopus japonicus.
Five glucocerebroside molecular species, SJC-1-SJC-5, have been isolated from the less polar lipid fraction of a chloroform/methanol extract of the sea cucumber Stichopus japonicus. The structures of these glucocerebroside molecular species were determined on the basis of chemical and spectroscopic evidence. SJC-1, SJC-2, and SJC-3 are typical sphingosine- and phytosphingosine-type glucocerebroside molecular species with nonhydroxylated and hydroxylated fatty acyl moieties. SJC-4 and SJC-5 are also sphingosine-type glucocerebroside molecular species with hydroxylated fatty acyl moieties, although they are new glucocerebroside molecular species with unique sphingosine bases.
Kisa
Fumiaki
F
Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka.
Yamada
Koji
K
Kaneko
Masafumi
M
Inagaki
Masanori
M
Higuchi
Ryuichi
R
D000818:Animals; D008401:Gas Chromatography-Mass Spectrometry; D005963:Glucosylceramides / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D000432:Methanol; D008968:Molecular Conformation; D012616:Sea Cucumbers / Q000737:chemistry*; D012997:Solvents; D013055:Spectrophotometry, Infrared
D005963:Glucosylceramides; D012997:Solvents; D000432:Methanol