title: Capella's gastroplasty: metabolites and acute phase proteins changes in midline and bilateral arciform approaches.
abstract: BACKGROUND
  Obesity has adverse health effects. Dietary reeducation does not seem to offer sustained weight loss. For appropriately selected patients, surgery may be beneficial.
  
  
  OBJECTIVE
  To evaluate early postoperative metabolic response to surgery in patients submitted to Capella's gastroplasty using two different surgical approaches to the abdominal cavity.
  
  
  METHODS
  Twenty patients (9 males and 11 females, aged 21 to 53 years) were randomized prior to submission to either one of the surgical access incisions (bilateral arciform or supra-umbilical midline incisions). Blood samples were collected at the beginning and end of the operation, 12 (T-12 h) and 24 hours (T-24 h) postoperatively. Dieresis and synthesis time, blood loss, planimetry of operative field, operative time, hospital stay, hemoglobin, hematocrit, lymphocytes, potassium, albumin, erythrocyte sedimentation rate, C-reactive protein, glucose, pyruvate, lactate and ketone bodies were analyzed.
  
  
  RESULTS
  Dieresis time was significantly decreased when median approach was used. Total operating time, hospital stay, hematocrit, hemoglobin, lymphocyte count, potassium and albumin concentrations were similar in both groups. C-reactive protein (T-12 h), glucose and pyruvate concentrations (T-24 h) increased significantly after completion of surgical procedure. Ketone bodies concentrations were significantly decreased 24 hour following completion of surgical procedure.
  
  
  CONCLUSIONS
  Capella's gastroplasty induces metabolic and inflammatory changes in blood parameters. There is no evidence of technical superiority of arciform over midline incisions in this study.
authors.affiliation: Post-graduation Program, Faculty of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil.
authors.forename: Luiz Gonzaga
authors.initials: LG
authors.lastname: de Moura
authors.forename: Sérgio Botelho
authors.initials: SB
authors.lastname: Guimarães
authors.forename: Heládio Feitosa
authors.initials: HF
authors.lastname: de Castro-Filho
authors.forename: Heine Ferreira
authors.initials: HF
authors.lastname: Machado
authors.forename: Francisca das Chagas
authors.initials: Fd
authors.lastname: Feijó
authors.forename: Paulo Roberto Leitão
authors.initials: PR
authors.lastname: de Vasconcelos
mesh_terms: D000209:Acute-Phase Proteins / Q000032:analysis* / Q000378:metabolism; D000328:Adult; D005260:Female; D015391:Gastroplasty / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000378:metabolism / Q000601:surgery*
chemical_list: D000209:Acute-Phase Proteins