title: Controlling diastereoselectivity in the reactions of enantiomerically pure alpha-bromoacyl-imidazolidinones with nitrogen nucleophiles: substitution reactions with retention or inversion of configuration.
abstract: Diastereoselective substitution reactions of [small alpha]-bromoacyl-imidazolidinones with nitrogen nucleophiles can be promoted with either retention or inversion of configuration by carrying out reactions under epimerising or non-epimerising conditions.
authors.affiliation: Department of Chemistry, University College London, 20 Gordon Street, London, UK.
authors.forename: N R
authors.initials: NR
authors.lastname: Treweeke
authors.forename: P B
authors.initials: PB
authors.lastname: Hitchcock
authors.forename: D A
authors.initials: DA
authors.lastname: Pardoe
authors.forename: S
authors.initials: S
authors.lastname: Caddick
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D001965:Bromides / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry; D007093:Imidazoles / Q000737:chemistry*; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D001965:Bromides; D002264:Carboxylic Acids; D007093:Imidazoles; C010862:azolimine; D009584:Nitrogen