L-valyl-L-serine trihydrate.
The valine side chains in the crystal structure of the title compound [systematic name: 2-(2-ammonio-3-methylbutanamido)-3-hydroxypropanoate trihydrate], C8H16N2O4.3H2O, stack along an a axis of 4.77 A to form hydrophobic columns surrounded by remarkable water/hydroxyl shells. The peptide main chains are connected by hydrogen bonds in two-dimensional layers. The peptide molecules in each layer are related only by translation, and generate a very rare pattern. This is rendered possible through the formation of the shortest C(alpha)-H...O(carboxylate) interaction ever recorded.
Johansen
Arne
A
Department of Chemistry, University of Oslo, PO Box 1033 Blindern, N-0315 Oslo, Norway.
Midtkandal
Randi
R
Roggen
Heidi
H
Görbitz
Carl Henrik
CH
D018360:Crystallography, X-Ray; D004151:Dipeptides / Q000737:chemistry*; D006860:Hydrogen Bonding; D012694:Serine / Q000737:chemistry*; D014633:Valine / Q000737:chemistry*
D004151:Dipeptides; D012694:Serine; D014633:Valine