[Clinical, tomographic and immunogenetic study of patients with infantile cerebral palsy].
A neurovisual and immunogenetic study of patients with different forms of cerebral palsy was conducted. Morphological peculiarities of each form were described. A frequent combination of pathology of cerebrospinal fluid spaces and periventricular area with disruption of neuronal migration and development of brain mass and volume was found. HLA-typing revealed a significant association of the disease with antigen B13. An association of cerebral palsy with particular genetically determined vulnerability of fetal brain to lesions disrupting genetic program for neuroontogenesis is suggested.
Ismagilov
M F
MF
Gaĭnetdinova
D D
DD
Semenov
V V
VV
Pakhalina
I A
IA
D000293:Adolescent; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D002547:Cerebral Palsy / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics / Q000276:immunology / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D005787:Gene Frequency; D006680:HLA Antigens; D006650:Histocompatibility Testing; D006801:Humans; D007125:Immunogenetics; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D010641:Phenotype; D014057:Tomography, X-Ray Computed
D006680:HLA Antigens