title: [Renovascular hypertension--diagnosis and therapy].
abstract: Atherosclerotic renal artery stenosis accounts for most cases of renovascular hypertension (RVH). Hypertensive patients with clinical features suggesting RVH should be submitted to further noninvasive evaluation including duplex Doppler ultrasonography, CT- or MR angiography. Invasive evaluation by contrast-enhanced angiography confirms the diagnosis of renal artery stenosis. However, neither diagnostic test reliably predicts the course of hypertension after revascularisation. The therapeutic approach in hypertensive patients with hemodynamically important renal artery stenosis includes medical or invasive therapy (renal percutaneous transluminal angioplasty, PTRA; renal arterial stent placement, PTRAS; surgical revascularisation). Randomized trials comparing invasive and conservative approaches demonstrated no differences in blood pressure control or renal function. Only patients with clear clinical indications should be submitted to interventional procedures as PTRA, PTRAS and surgical vascular intervention.
authors.affiliation: Medizinische Klinik II, Universitätsklinikum Aachen. jriehl@ukaachen.de
authors.forename: J
authors.initials: J
authors.lastname: Riehl
authors.forename: E
authors.initials: E
authors.lastname: Spüntrup
authors.forename: B
authors.initials: B
authors.lastname: Heintz
authors.forename: R W
authors.initials: RW
authors.lastname: Günther
authors.forename: J
authors.initials: J
authors.lastname: Floege
mesh_terms: D000800:Angioplasty, Balloon; D002986:Clinical Trials as Topic; D006801:Humans; D006978:Hypertension, Renovascular / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D012078:Renal Artery Obstruction / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors