title: Novel movement disorder of the lower lip: is it epilepsia partialis continua? Clues from a secondary case.
abstract: A 28-year-old woman developed an acute-onset novel movement disorder of the lower lip mimicking focal dystonia. Investigations showed it to be a presentation of epilepsia partialis continua occurring in association with agenesis of the corpus callosum. It responded favorably to anti-epileptic drug therapy. Recently, Kleopa and Kyriakides reported on 4 patients who developed sudden-onset movement disorder characterized by a tonic sustained, lateral and outward protrusion of half of the lower lip. They failed to find any causative factors, despite extensive investigation. Treatment with anticholinergics, clonazepam, and botulinum toxin injection failed to improve the movement disorder. I present an additional case of similar focal movement disorder occurring in the presence of agenesis of the corpus callosum. A scalp electroencephalogram revealed focal epileptic activity, and the movement disorder responded favorably to treatment with antiepileptic drugs.
authors.affiliation: Jawaharlal Nehru Medical College, Karnataka Lingayat Education Society's Hospital and Medical Research Centre, Belgaum, Karnataka State, India. walidoc@hotmail.com
authors.forename: Gurusidheshwar M
authors.initials: GM
authors.lastname: Wali
mesh_terms: D000328:Adult; D003337:Corpus Callosum / Q000473:pathology; D004569:Electroencephalography / Q000379:methods; D005260:Female; D006801:Humans; D008046:Lip / Q000503:physiopathology*; D008279:Magnetic Resonance Imaging / Q000379:methods; D009069:Movement Disorders / Q000473:pathology* / Q000503:physiopathology*; D012535:Scalp / Q000503:physiopathology