Best evidence topic report. Glucagon infusion in refractory anaphylactic shock in patients on beta-blockers.
A short cut review was carried out to establish whether a glucagon infusion is of benefit in patients with refractory anaphylaxis. 62 papers were found using the reported search, of which two presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results, and study weaknesses of these best papers are tabulated. A clinical bottom line is stated.
Thomas
Martin
M
Crawford
Ian
I
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000707:Anaphylaxis / Q000150:complications / Q000188:drug therapy*; D000787:Angina Pectoris / Q000150:complications / Q000188:drug therapy; D001262:Atenolol / Q000627:therapeutic use; D004638:Emergency Treatment / Q000379:methods; D005934:Glucagon / Q000008:administration & dosage*; D006801:Humans; D007022:Hypotension / Q000188:drug therapy / Q000209:etiology; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged
D000319:Adrenergic beta-Antagonists; D001262:Atenolol; D005934:Glucagon