title: Urothelial changes induced by therapeutic procedures for bladder cancer. A review.
abstract: Topical and systemic therapeutic agents and treatment modalities, such as thiotepa and mitomycin C, cyclophosphamide, bacillus Calmette-Guerin, radiation therapy, photodynamic and laser therapy, and gene therapy, produce a host of changes in the bladder, some of them mimicking cancer. Pathologists must be aware that following these types of treatment, the clinical utility of urinary cytology is reduced.
authors.affiliation: Section of Pathologic Anatomy and Histopathology and Institute of Urology, School of Medicine, Polytechnic University of the Marche Region, Ancona, Italy. rmaz@libero.it
authors.forename: Roberta
authors.initials: R
authors.lastname: Mazzucchelli
authors.forename: Francesca
authors.initials: F
authors.lastname: Barbisan
authors.forename: Lucia M
authors.initials: LM
authors.lastname: Tarquini
authors.forename: Marco
authors.initials: M
authors.lastname: Streccioni
authors.forename: Andrea B
authors.initials: AB
authors.lastname: Galosi
mesh_terms: D015316:Genetic Therapy; D006801:Humans; D007167:Immunotherapy; D010778:Photochemotherapy; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D019459:Urothelium / Q000187:drug effects / Q000473:pathology* / Q000528:radiation effects