title: Glioblastoma multiforme metastasis to the axis. Case report.
abstract: Extracranial bone metastasis from glioblastoma multiforme (GBM) has rarely been reported in the literature, and most metastatic GBMs are multiple bone metastases. The authors describe the first case of a GBM with metastasis only to the axis. This 42-year-old man presented with a 2-month history of headache, nausea, vomiting, and disorientation. Magnetic resonance imaging demonstrated a right temporal tumor, which was diagnosed as a GBM based on tumor resection. The patient was treated using radiation (6000 cGy) and the intravenous administration of nimustine hydrochloride. Eighteen months thereafter, he experienced the sudden onset of neck pain. Magnetic resonance studies revealed a tumor in the axis that was diagnosed as GBM based on biopsy procedure.
authors.affiliation: Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Kanagaw, Japan. utsuki@med.kitasato-u.ac.jp
authors.forename: Satoshi
authors.initials: S
authors.lastname: Utsuki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Tanaka
authors.forename: Hidehiro
authors.initials: H
authors.lastname: Oka
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Iwamoto
authors.forename: Takao
authors.initials: T
authors.lastname: Sagiuchi
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Fujii
mesh_terms: D000328:Adult; D001368:Axis, Cervical Vertebra; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology*; D005909:Glioblastoma / Q000175:diagnosis / Q000473:pathology* / Q000556:secondary; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000556:secondary*