Mega-dose carbamazepine complicating third trimester of pregnancy.
A case of coma due to carbamazepine ingestion with the intention of committing suicide at 33 weeks' gestation is presented. Management included activated charcoal administration and exchange plasmapheresis. A fetal non-stress test was non-reassuring but the Apgar score, cord blood gases and early neonatal outcome were normal. Differential diagnosis of coma in pregnancy should include investigation for drug intoxication.
Saygan-Karamursel
Burcu
B
Department of Obstetrics and Gynecology, Hacettepe University School of Medicine, Ankara, Turkey.
Guven
Suleyman
S
Onderoglu
Lutfi
L
Deren
Ozgur
O
Durukan
Tekin
T
D000328:Adult; D000927:Anticonvulsants / Q000097:blood / Q000633:toxicity*; D002220:Carbamazepine / Q000097:blood / Q000633:toxicity*; D015148:Cardiotocography; D003937:Diagnosis, Differential; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D006340:Heart Rate, Fetal; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications; D011263:Pregnancy Trimester, Third; D013406:Suicide, Attempted
D000927:Anticonvulsants; D002220:Carbamazepine