Predicting coronary heart disease risk using multiple lipid measures.
Principal component analysis was used to summarize variations among 7 lipid measures included in the Framingham Offspring Study (n = 2,694). An overall measure combining information from the 7 lipids was compared with conventional lipid measures in adjusted survival analyses and was found to be a superior predictor of coronary heart disease risk.
Everett
Charles J
CJ
Department of Family Medicine, Medical University of South Carolina, Charleston 29425, USA. everettc@musc.edu <everettc@musc.edu>
Mainous
Arch G
AG
Koopman
Richelle J
RJ
Diaz
Vanessa A
VA
D000328:Adult; D000368:Aged; D003327:Coronary Disease / Q000209:etiology*; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications*; D008137:Longitudinal Studies; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D012307:Risk Factors; D016019:Survival Analysis