title: Renal artery stenosis and aneurysms associated with neurofibromatosis.
abstract: Renal artery lesions associated with neurofibromatosis may involve stenosis and aneurysm formation at all levels of the renal artery to the intraparenchymal branches, and usually are associated with hypertension. A 13-year-old boy with type I neurofibromatosis and severe hypertension presented with multiple aneurysms and multiple stenotic lesions in the renal artery and segmental arteries. The patient underwent ex-vivo renal artery repair with autologous hypogastric artery and autotransplantation to the iliac fossa and was clinically improved. The characteristic histologic findings are presented. A review of the recent literature comparing different treatment modalities for renovascular hypertension in children with neurofibromatosis suggests that surgery remains the best treatment alternative.
authors.affiliation: Division of Vascular Surgery, Department of Surgery, State University of New York at Stony Brook, Stony Brook, NY 11794, USA.
authors.forename: Myo
authors.initials: M
authors.lastname: Han
authors.forename: Enrique
authors.initials: E
authors.lastname: Criado
mesh_terms: D000293:Adolescent; D000783:Aneurysm / Q000150:complications*; D001158:Arteries / Q000637:transplantation; D006801:Humans; D006978:Hypertension, Renovascular / Q000209:etiology / Q000601:surgery; D008297:Male; D009456:Neurofibromatosis 1 / Q000150:complications*; D012077:Renal Artery / Q000473:pathology; D012078:Renal Artery Obstruction / Q000150:complications* / Q000601:surgery