title: Anaerobic exercise capacity in patients with juvenile-onset idiopathic inflammatory myopathies.
abstract: OBJECTIVE
  To 1) report the feasibility of an "all-out" 30-second cycling exercise test (Wingate Anaerobic Exercise Test [WAnT]) in juvenile-onset idiopathic inflammatory myopathy (JIIM) patients, 2) describe the anaerobic exercise capacity in juvenile dermatomyositis patients, and 3) determine if the anaerobic exercise capacity could be related to disease duration or disease phase.
  
  
  METHODS
  Twenty patients (age 14.13 +/- 5.4 years) with JIIM participated in this study. All patients were able to perform the WAnT without adverse events.
  
  
  RESULTS
  Comparison with healthy controls revealed a -29.3 +/- 26.58% (P = 0.001) and -27.6 +/- 25.7% (P = 0.002) impairment in mean power and peak power on the WAnT, respectively. The WAnT correlated with disease phase and with knee extensor muscle strength.
  
  
  CONCLUSIONS
  The WAnT might be a valuable adjunct next to other assessment tools in the followup of JIIM patients.
authors.affiliation: University Hospital for Children and Youth "Het Wilhelmina Kinderziekenhuis," University Medical Center Utrecht, Utrecht, The Netherlands. t.takken@wkz.azu.nl
authors.forename: Tim
authors.initials: T
authors.lastname: Takken
authors.forename: Janjaap
authors.initials: J
authors.lastname: van der Net
authors.forename: Paul J M
authors.initials: PJ
authors.lastname: Helders
mesh_terms: D000293:Adolescent; D000328:Adult; D000693:Anaerobiosis / Q000502:physiology; D002648:Child; D003882:Dermatomyositis / Q000503:physiopathology*; D015444:Exercise; D005080:Exercise Test; D017079:Exercise Tolerance; D005240:Feasibility Studies; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal / Q000503:physiopathology*; D011795:Surveys and Questionnaires; D013997:Time Factors