Metastatic retinoblastoma of the maxilla and mandible.
Metastatic retinoblastoma of the jaws is very rare. We present a 4-year-old boy with metastatic retinoblastoma that involved both the maxilla and mandible simultaneously. Enhanced CT indicated bone-destructive masses with partially non-enhanced area and enhanced margin in the right maxilla and left mandible. MRI showed well-delineated masses that were isointense on T(1) weighted images and hyperintense on T(2) weighted images. Four weeks after chemotherapy and bone marrow transplantation, the size of lesions remarkably decreased. The patient died 19 months later with extensive tumour metastases despite additional chemotherapy. In this case, the dental crypt of a permanent tooth was considered the potential target through which retinoblastoma metastasized to the jaws.
Taguchi
A
A
Department of Oral and Maxillofacial Radiology, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan. akiro@hiroshima-u.ac.jp
Suei
Y
Y
Ogawa
I
I
Naito
K
K
Nagasaki
T
T
Lee
K
K
Fujita
M
M
Tanimoto
K
K
D002675:Child, Preschool; D005134:Eye Neoplasms / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D008441:Maxillary Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D011862:Radiography, Panoramic; D012175:Retinoblastoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D014057:Tomography, X-Ray Computed