title: Live birth of healthy triplets after in vitro fertilization and embryo transfer in an acromegalic woman with elevated growth hormone.
abstract: OBJECTIVE
  To report a case of successful triplet pregnancy in an acromegaly patient with IVF and embryo transfer.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Tertiary center for assisted reproductive technologies.
  
  
  METHODS
  A 33-year-old woman with acromegaly and primary infertility.
  
  
  METHODS
  Controlled ovulation hyperstimulation and IVF/embryo-transfer treatment using gonadotropins.
  
  
  METHODS
  Uncomplicated pregnancy course and successful take-home triplet infant girls.
  
  
  RESULTS
  Successful ovarian stimulation and IVF is possible in acromegalic patients.
  
  
  CONCLUSIONS
  There may be an effect of elevated growth hormone resulting in increased ovarian response to gonadotropin, inducing hyperstimulation and high-order multiple pregnancies in these patients.
authors.affiliation: Toronto Centre for Advanced Reproductive Technology, Toronto, Ontario, Canada.
authors.forename: Navid
authors.initials: N
authors.lastname: Esfandiari
authors.forename: Lynda
authors.initials: L
authors.lastname: Gotlieb
authors.forename: Robert F
authors.initials: RF
authors.lastname: Casper
mesh_terms: D000172:Acromegaly / Q000097:blood* / Q000453:epidemiology; D000328:Adult; D015897:Comorbidity; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006062:Gonadotropins / Q000494:pharmacology / Q000627:therapeutic use; D019382:Human Growth Hormone / Q000097:blood*; D006801:Humans; D007247:Infertility, Female / Q000097:blood / Q000453:epidemiology / Q000628:therapy*; D010060:Ovulation / Q000187:drug effects / Q000502:physiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood* / Q000453:epidemiology; D011256:Pregnancy Outcome / Q000453:epidemiology*; D014310:Triplets / Q000502:physiology*
chemical_list: D006062:Gonadotropins; D019382:Human Growth Hormone