Interaction between surgical procedure for repairing retinal detachment and clinical risk factors for proliferative vitreoretinopathy.
OBJECTIVE
To asses risk factors of proliferative vitreoretinopathy (PVR) and a model for predicting it.


METHODS
Observational, case-control. 335 patients with non-complicated retinal detachment (RD) were included: 134 developed PVR (Cases); 201 patients did not (Controls). Risk factors for PVR were identified by multivariate analysis. Influence of variables was assayed according to the surgical approach. By logistic regression analysis a model to predict the risk of developing PVR and odds ratio (OR) values for each clinical factor were estimated.


RESULTS
Risk was higher in patients > 70 years and with intraocular pressure lower than 14 (OR: 3.84; CI 95%: 2.04-7.30) and in retinal breaks larger than "1 clock hour" (OR: 2.54; CI: 1.28-5.05), extended retinal detachments (OR: 4.01; CI: 1.98-8.10) and reinterventions (OR: 1.55; CI: 1.14-9.22). Scleral surgery also was a risk factor (OR: 3.89; CI: 2.12-7.14) and aphakia/pseudophakia when scleral surgery is performed (OR: 3.33; CI: 1.54-7.22). A model to predict PVR was proposed with these results.


CONCLUSIONS
Surgical approach modifies risk factors of PVR, and should be taken into account to improve the models for predicting it.
Rodriguez de la Rúa
E
E
Retina Group, Instituto Universitario de Oftalmobiología Aplicada (IOBA), University of Valladolid, Valladolid, Spain.
Pastor
J C
JC
Aragón
J
J
Mayo-Iscar
A
A
Martínez
V
V
García-Arumí
J
J
Giraldo
A
A
Sanabria-Ruiz Colmenares
M R
MR
Miranda
I
I
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D016017:Odds Ratio; D013508:Ophthalmologic Surgical Procedures; D011183:Postoperative Complications; D012372:ROC Curve; D012163:Retinal Detachment / Q000601:surgery*; D012307:Risk Factors; D018630:Vitreoretinopathy, Proliferative / Q000209:etiology*