title: The process development challenge for a new vaccine.
abstract: The challenges of vaccine development are not limited to identification of suitable antigens, adjuvants and delivery methods, but include regulatory, technical and manufacturing hurdles in translating a vaccine candidate to the clinic. Process development is the technological foundation that underlies the manufacture of new vaccines and is central to successful commercialization.
authors.affiliation: Merck Research Laboratories, West Point, Pennsylvania 19486, USA. barry_buckland@merck.com
authors.forename: Barry C
authors.initials: BC
authors.lastname: Buckland
mesh_terms: D006562:Herpes Zoster / Q000517:prevention & control; D022283:Herpesvirus Vaccines; D006801:Humans; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000517:prevention & control; D022243:Rotavirus Vaccines; D013678:Technology, Pharmaceutical; D014612:Vaccines
chemical_list: D022283:Herpesvirus Vaccines; D022243:Rotavirus Vaccines; D014612:Vaccines