title: [Melanotic neurofibroma, clinical and histopathologic diagnosis. Case report].
abstract: Melanotic neurofibroma is a rare benign tumor, derived from peripheral nerve sheath, whose originality consists in the presence of melanic pigment. The clinical diagnosis is difficult to establish, requiring the histopathological exam to make the difference between melanotic neurofibroma and the other pigmented tumors. Although, sometimes neither the anatomopathological exam can establish the final diagnosis, requiring supplementary studies. Melanotic neurofibroma has a good prognosis and the malignization is rare. The elective treatment is surgical, represented by the complete excision of the tumor.
authors.affiliation: Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Bioinginerie, Disciplina de Dermatologie.
authors.forename: Anca
authors.initials: A
authors.lastname: Zbranca
authors.forename: Raluca
authors.initials: R
authors.lastname: Stefan
authors.forename: Mirela
authors.initials: M
authors.lastname: Grigorovici
authors.forename: Mirela
authors.initials: M
authors.lastname: Cherciu
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008161:Lumbosacral Region; D008543:Melanins / Q000032:analysis*; D020460:Melanosomes / Q000473:pathology; D009455:Neurofibroma / Q000175:diagnosis* / Q000601:surgery / Q000648:ultrastructure; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000601:surgery / Q000648:ultrastructure; D016896:Treatment Outcome
chemical_list: D008543:Melanins