In vivo scattering measurement of biological tissue by the use of a pyroelectric polymer transducer.
We propose a new method, to our knowledge, for noninvasive scattering measurements of tissues by the use of a pyroelectric polymer transducer, poly(vinylidene fluoride trifluoroethylene) film. In this method, samples are irradiated with nanosecond, low-energy light pulses delivered from an optical fiber, and the pyroelectric signal induced by the diffuse reflectance is measured with a transducer. The signal is then converted into diffuse reflectance by use of a calibration factor. The validity of this method was confirmed by our measuring the scattering coefficient of a white acrylic resin within an accuracy of +/- 15%. We attempted to apply this method to the estimation of scattering coefficients of normal and burned skins in rats in vivo.
Yamazaki
Mutsuo
M
Department of Electronics and Electrical Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan. yamazaki@obara.elec.keio.ac.jp
Sato
Shunichi
S
Saitoh
Daizoh
D
Obara
Minoru
M
D000818:Animals; D002056:Burns / Q000175:diagnosis* / Q000503:physiopathology*; D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005336:Fiber Optic Technology / Q000295:instrumentation*; D008027:Light; D055100:Optical Fibers; D051381:Rats; D012031:Refractometry / Q000295:instrumentation*; D015203:Reproducibility of Results; D012542:Scattering, Radiation; D012680:Sensitivity and Specificity; D012867:Skin / Q000293:injuries* / Q000503:physiopathology*; D014159:Transducers