title: Splenic accumulation of Tc-99m HMDP in a patient with severe alcoholic cirrhosis of the liver.
abstract: The authors report unusual splenic accumulation of Tc-99m hydroxymethylene diphosphonate (HMDP) on bone scintigraphy of a patient with alcoholic cirrhosis of the liver. Laboratory studies showed hemolytic anemia and hemochromatosis resulting from alcohol abuse, both of which are thought to be related to the diffuse splenic uptake observed. When diffuse splenic accumulation by Tc-99m HMDP is seen, the existence of alcoholic hepatopathy might be considered.
authors.affiliation: Department of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan. etsushi-k@med.osaka-cu.ac.jp
authors.forename: Etsushi
authors.initials: E
authors.lastname: Kawamura
authors.forename: Joji
authors.initials: J
authors.lastname: Kawabe
authors.forename: Takehiro
authors.initials: T
authors.lastname: Hayashi
authors.forename: Ai
authors.initials: A
authors.lastname: Oe
authors.forename: Jin
authors.initials: J
authors.lastname: Kotani
authors.forename: Kenji
authors.initials: K
authors.lastname: Torii
authors.forename: Daiki
authors.initials: D
authors.lastname: Habu
authors.forename: Susumu
authors.initials: S
authors.lastname: Shiomi
mesh_terms: D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000000981:diagnostic imaging* / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D012720:Severity of Illness Index; D013154:Spleen / Q000000981:diagnostic imaging* / Q000378:metabolism*; D013669:Technetium Tc 99m Medronate / Q000031:analogs & derivatives* / Q000493:pharmacokinetics
chemical_list: D019275:Radiopharmaceuticals; C024226:technetium Tc 99m hydroxymethylene diphosphonate; D013669:Technetium Tc 99m Medronate