Physical activity patterns in chronic hemodialysis patients: comparison of dialysis and nondialysis days.
OBJECTIVE
To determine physical activity patterns in chronic hemodialysis patients with a specific emphasis on the difference between dialysis and nondialysis days. Design A cross-sectional single-center study.


METHODS
Vanderbilt University Outpatient Dialysis Unit.


METHODS
Twenty current chronic hemodialysis patients: 10 male, 10 female; 15 black, 5 white; mean age, 50.1 +/- 9.9 years; height, 164.5 +/- 10.9 cm; weight, 82.5 +/- 15.4 kg; length on dialysis, 57.3 +/- 45.3 months.


METHODS
Minute-by-minute physical activity was assessed over a 7-day period using a triaxial accelerometer, which consists of raw numbers or counts calculated by the 3 axes of the accelerometer (PA counts). PA counts were extrapolated on a daily and hourly basis. Physical functioning tests included: sit-to-stand, 6-minute walk, and 1-repetition maximal leg press exercise. Laboratory values for serum concentrations of albumin, prealbumin, C-reactive protein, and cholesterol were also collected.


METHODS
PA counts.


RESULTS
Total PA counts were significantly lower on dialysis days when compared with nondialysis days (128,279 +/- 74,009 versus 168,744 +/- 95,168, respectively, P = .025). The average PA counts during the 4-hour dialysis time period were significantly lower on dialysis days when compared with nondialysis days (3,086 +/- 3,749 versus 11,070 +/- 7,695, respectively, P = .001). At postdialysis hours 1 and 2, PA counts on dialysis days were significantly higher than on nondialysis days (11,410 +/- 5,340 versus 9,082 +/- 6,646, P = .008, and 14,048 +/- 9,728 versus 8,662 +/- 6,433, P = .016, respectively). By postdialysis hour 4, PA counts on dialysis days had significantly decreased when compared with nondialysis days (6,068 +/- 6,268 versus 10,512 +/- 7,420 PA counts, P = .01, respectively). From postdialysis hours 5 to 20, there was no significant difference in PA counts between dialysis and nondialysis days.


CONCLUSIONS
This study shows that physical activity is lower on dialysis days when compared with nondialysis days, and this decrease is caused by the lack of activity during the 4-hour hemodialysis procedure. New behavior modification strategies involving physical activity, both during hemodialysis and on nondialysis days, must be examined in this patient population.
Majchrzak
Karen M
KM
Department of Medicine, Division of Nephrology, Vanderbilt University School of Medicine, Nashville, TN, USA.
Pupim
Lara B
LB
Chen
Kong
K
Martin
Cathi J
CJ
Gaffney
Sheila
S
Greene
Jane H
JH
Ikizler
T Alp
TA
D015502:Absorptiometry, Photon; D000328:Adult; D001823:Body Composition; D002097:C-Reactive Protein / Q000032:analysis; D002784:Cholesterol / Q000097:blood; D003430:Cross-Sectional Studies; D004734:Energy Metabolism; D015444:Exercise / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D011228:Prealbumin / Q000032:analysis; D006435:Renal Dialysis; D012709:Serum Albumin / Q000032:analysis; D013997:Time Factors
D011228:Prealbumin; D012709:Serum Albumin; D002097:C-Reactive Protein; D002784:Cholesterol