title: Polish population study on Y chromosome haplotypes defined by 18 STR loci.
abstract: Polymorphism of 18 STR loci specific to the human Y chromosome (DYS19, DYS388, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS426, DYS437, DYS438, DYS439, DYS460, GATA H4.1, DYS385 a/b, and YCAII a/b) was evaluated by means of a multiplex (octadecaplex) PCR reaction and capillary electrophoresis in a Polish population sample of 208 unrelated males. A total of 192 different haplotypes and 183 unique haplotypes were identified. The observed haplotype diversity was 0.998, while discrimination capacity was 92.3%. DYS389 was shown to be the most valuable in discrimination of similar haplotypes, whereas DYS388, DYS393, DYS426, and DYS438 did not affect the discrimination power of the multiplex.
authors.affiliation: Department of Forensic Medicine, Medical University of Gdańsk, ul. Marii Skłodowskiej-Curie 3A, 80-210, Gdańsk, Poland. k.rebala@amg.gda.pl
authors.forename: K
authors.initials: K
authors.lastname: Rebała
authors.forename: Z
authors.initials: Z
authors.lastname: Szczerkowska
mesh_terms: D000483:Alleles; D041322:Chromosomes, Human, Y / Q000235:genetics*; D005828:Genetics, Population; D006239:Haplotypes / Q000235:genetics*; D006801:Humans; D008297:Male; D011044:Poland; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences / Q000235:genetics*