Obsessive-compulsive symptoms in clozapine-treated schizophrenic patients.
The aim of the present study was to assess the occurrence of obsessive-compulsive symptoms (OCS) in schizophrenic patients treated with clozapine, and to examine the relationship between OCS and other clinical variables. The results support earlier findings which suggest that clozapine produces or unmasks OCS. In addition, the severity of OCS was not related to other dimensions of psychopathology, severity of illness, clinical improvement or dose and duration of clozapine treatment.
Ertugrul
Aygun
A
Hacettepe University Faculty of Medicine, Department of Psychiatry, Ankara 06100, Turkey. aertugru@hacettepe.edu.tr
Anil Yagcioglu
A Elif
AE
Eni
Nurhayat
N
Yazici
Kâzim M
KM
D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D003024:Clozapine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000150:complications* / Q000188:drug therapy* / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000150:complications* / Q000188:drug therapy*; D012565:Schizophrenic Psychology; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use
D014150:Antipsychotic Agents; D003024:Clozapine; D017367:Selective Serotonin Reuptake Inhibitors