title: Nonparallelism between reaction rate and dienophile-catalyst affinity in catalytic enantioselective Diels-Alder reactions.
abstract: [reaction: see text] The above reaction is much faster with Y = CF(3)CH(2)O than with Y = CH(3)O. However, the methyl ester is a strong inhibitor of the Diels-Alder reaction of the trifluoroethyl ester, since it has a higher affinity for the catalyst 1.
authors.affiliation: Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
authors.forename: Do Hyun
authors.initials: DH
authors.lastname: Ryu
authors.forename: Gang
authors.initials: G
authors.lastname: Zhou
authors.forename: E J
authors.initials: EJ
authors.lastname: Corey