Complete myocardial revascularization: between myth and reality.
Myocardial revascularization in patients with multi-vessel coronary artery disease may be accomplished, by percutaneous interventions or surgery, either on all diseased lesions or directed to selectively targeted coronary segments. The extent of planned revascularization is often a major determinant of treatment strategy. Revascularization of all diseased coronary segments-complete myocardial revascularization-has a potential long-term benefit, but is more complex and may increase in-hospital untoward events. Revascularization may otherwise be incomplete, either because of the operator's inability to treat all diseased coronary segments or by choice of deciding to selectively revascularize only large areas of myocardium at risk. Although incomplete revascularization may negatively affect long-term outcomes, it may be, when wisely chosen, the preferred treatment strategy in selected patient categories because of its lower immediate risks. The patient's clinical status, ventricular function, and the presence of co-morbidities may orient clinical decisions in favour of incomplete revascularization.
Zimarino
Marco
M
Institute of Cardiology and Centre of Excellence on Aging, 'G. d'Annunzio' University, Ospedale S. Camillo de Lellis, Via Forlanini, 50, 66100 Chieti, Italy. m.zimarino@unich.it
Calafiore
Antonio Maria
AM
De Caterina
Raffaele
R
D015906:Angioplasty, Balloon, Coronary / Q000379:methods; D002986:Clinical Trials as Topic; D003327:Coronary Disease / Q000628:therapy*; D018572:Disease-Free Survival; D006801:Humans; D007674:Kidney Diseases / Q000150:complications; D009204:Myocardial Revascularization / Q000379:methods*; D011183:Postoperative Complications / Q000209:etiology; D012307:Risk Factors; D015607:Stents; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000209:etiology