The direct acyl-alkylation of arynes.
An efficient and mild acyl-alkylation of arynes is described. The method is used to synthesize medium-sized carbocycles by the ring-expansion of cyclic beta-ketoesters.
Tambar
Uttam K
UK
Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.
Stoltz
Brian M
BM