title: A toxicologic and dermatologic assessment of cinnamyl alcohol, cinnamaldehyde and cinnamic acid when used as fragrance ingredients.
authors.affiliation: Department of Dermatology, College of Physicians and Surgeons of Columbia University, 161 Fort Washington Avenue, New York, NY 10032, USA.
authors.forename: D
authors.initials: D
authors.lastname: Bickers
authors.forename: P
authors.initials: P
authors.lastname: Calow
authors.forename: H
authors.initials: H
authors.lastname: Greim
authors.forename: J M
authors.initials: JM
authors.lastname: Hanifin
authors.forename: A E
authors.initials: AE
authors.lastname: Rogers
authors.forename: J H
authors.initials: JH
authors.lastname: Saurat
authors.forename: I G
authors.initials: IG
authors.lastname: Sipes
authors.forename: R L
authors.initials: RL
authors.lastname: Smith
authors.forename: H
authors.initials: H
authors.lastname: Tagami
mesh_terms: D000171:Acrolein / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000378:metabolism / Q000493:pharmacokinetics; D000284:Administration, Oral; D000818:Animals; D002934:Cinnamates / Q000009:adverse effects / Q000378:metabolism / Q000493:pharmacokinetics; D017484:Dermatitis, Phototoxic / Q000209:etiology; D005260:Female; D005421:Flavoring Agents / Q000009:adverse effects / Q000378:metabolism / Q000493:pharmacokinetics; D006801:Humans; D006965:Hyperplasia / Q000139:chemically induced; D008297:Male; D009152:Mutagenicity Tests; D019055:No-Observed-Adverse-Effect Level; D010476:Perfume / Q000009:adverse effects / Q000378:metabolism / Q000493:pharmacokinetics; D020005:Propanols / Q000009:adverse effects / Q000378:metabolism / Q000493:pharmacokinetics; D012867:Skin / Q000473:pathology*; D012869:Skin Absorption; D014018:Tissue Distribution
chemical_list: D002934:Cinnamates; D005421:Flavoring Agents; D010476:Perfume; D020005:Propanols; C029010:cinnamic acid; D000171:Acrolein; C012843:cinnamaldehyde; C020722:cinnamyl alcohol