title: pFind: a novel database-searching software system for automated peptide and protein identification via tandem mass spectrometry.
abstract: Research in proteomics requires powerful database-searching software to automatically identify protein sequences in a complex protein mixture via tandem mass spectrometry. In this paper, we describe a novel database-searching software system called pFind (peptide/protein Finder), which employs an effective peptide-scoring algorithm that we reported earlier. The pFind server is implemented with the C++ STL, .Net and XML technologies. As a result, high speed and good usability of the software are achieved.
authors.affiliation: Institute of Computing Technology, Chinese Academy of Sciences Beijing 100080, China. dqli@jdl.ac.cn
authors.forename: Dequan
authors.initials: D
authors.lastname: Li
authors.forename: Yan
authors.initials: Y
authors.lastname: Fu
authors.forename: Ruixiang
authors.initials: R
authors.lastname: Sun
authors.forename: Charles X
authors.initials: CX
authors.lastname: Ling
authors.forename: Yonggang
authors.initials: Y
authors.lastname: Wei
authors.forename: Hu
authors.initials: H
authors.lastname: Zhou
authors.forename: Rong
authors.initials: R
authors.lastname: Zeng
authors.forename: Qiang
authors.initials: Q
authors.lastname: Yang
authors.forename: Simin
authors.initials: S
authors.lastname: He
authors.forename: Wen
authors.initials: W
authors.lastname: Gao
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D003628:Database Management Systems; D030562:Databases, Protein; D020869:Gene Expression Profiling / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods*; D011506:Proteins / Q000032:analysis / Q000737:chemistry* / Q000145:classification; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software; D014584:User-Computer Interface
chemical_list: D011506:Proteins