[Recent progress in molecular genetics and gene therapy for retinitis pigmentosa].
Retinitis pigmentosa (RP) is a common genetic eye disease affecting about 1 in 3500 people worldwide with pan-ethnic occurrence. So far there is no effective treatment for RP. This paper gives an overview on recent advances in molecular genetics of RP with emphasis on the important gene mutations for diagnosis and prognosis, and a review on gene therapy of RP.
Wang
Dan-Yi
DY
Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Fan
Bao-Jian
BJ
Wu
Xiang-Qian
XQ
Chan
Wai-Man
WM
Lam
Shun-Chiu
SC
Pang
Chi-Pui
CP
D015316:Genetic Therapy; D006801:Humans; D009154:Mutation; D012174:Retinitis Pigmentosa / Q000235:genetics* / Q000628:therapy