title: Direct, two-step synthetic pathway to novel dibenzo[a,c]phenanthridines.
abstract: Novel dibenzo[a,c]phenanthridines are prepared regioselectively by the application of a straightforward synthetic pathway, starting from new 3,4-diaryl- and 3,4-dihydro-3,4-diarylisoquinolines prepared via Ritter-type heterocyclization and the more classical two-step reductive amination/Bischler-Napieralski cyclization of triarylethanones, respectively. A comparative study of nonphenolic oxidative coupling methodologies provides a highly efficient procedure, based on the hypervalent iodine reagent phenyliodine(III) bis(trifluoroacetate) (PIFA), to accomplish the final coupling step.
authors.affiliation: Kimika Organikoa II Saila, Zientzi eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea, P.O. Box 644, 48080 Bilbao, Spain.
authors.forename: Fátima
authors.initials: F
authors.lastname: Churruca
authors.forename: Raul
authors.initials: R
authors.lastname: SanMartin
authors.forename: Mónica
authors.initials: M
authors.lastname: Carril
authors.forename: Miren Karmele
authors.initials: MK
authors.lastname: Urtiaga
authors.forename: Xavier
authors.initials: X
authors.lastname: Solans
authors.forename: Imanol
authors.initials: I
authors.lastname: Tellitu
authors.forename: Esther
authors.initials: E
authors.lastname: Domínguez