title: Preoperative assessment of surgical risk in oncogeriatric patients.
abstract: Cancer is a prevalent disease in our aging population; however, few oncologists are familiar with caring for oncogeriatric patients. Surgery is presently the treatment of choice for most solid tumors, but it is frequently delivered in a suboptimal way in this patient subsetting. Undertreatment is often justified with the concern of an unsustainable toxicity, while overtreatment can be related to the lack of knowledge in optimizing preoperative risk assessment. To draw new light on this issue, several surgeons presented their series, providing hard evidence that surgical options can be offered to the elderly with cancer, with only a limited postoperative mortality and morbidity. As it is likely that much of these data suffer from selection bias, we concentrated on Comprehensive Geriatric Assessment (CGA), which can add substantial information on the functional assessment of elderly cancer patients. A validated instrument such as the CGA allows a comparison of series, predicting short-term surgical outcomes more precisely, and offers appropriate information when consenting elderly patients. Preoperative Assessment of Cancer in the Elderly is a prospective international study conceived and launched to outline the fitness of elderly surgical patients with malignant tumors. This paper reports on preliminary results and analysis from the ongoing study.
authors.affiliation: University of Liverpool, Whiston Hospital, Prescot, L35 5DR, UK. raudisio@doctors.org.uk
authors.forename: Riccardo A
authors.initials: RA
authors.lastname: Audisio
authors.forename: Hodigere
authors.initials: H
authors.lastname: Ramesh
authors.forename: Walter E
authors.initials: WE
authors.lastname: Longo
authors.forename: Andrew P
authors.initials: AP
authors.lastname: Zbar
authors.forename: Daniel
authors.initials: D
authors.lastname: Pope
mesh_terms: D000203:Activities of Daily Living / Q000145:classification; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D003657:Decision Making; D005260:Female; D016330:Frail Elderly; D015577:Geriatric Assessment / Q000379:methods*; D006801:Humans; D017567:Karnofsky Performance Status; D008297:Male; D009369:Neoplasms / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology / Q000401:mortality; D011300:Preoperative Care / Q000295:instrumentation / Q000592:standards*; D011446:Prospective Studies; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D016896:Treatment Outcome