title: [Voice function and quality of life--patients with laryngeal carcinoma following minimal-invasive laser surgery and function voice rehabilitation].
abstract: BACKGROUND
  Quality of life is a relevant criterion for therapeutical outcome in laryngeal carcinoma patients. The aim of this study was to assess the self-related complaints in quality of life and functional outcome of voice among persons who had undergone laryngeal cancer surgery.
  
  
  METHODS
  The examination took place 67 months (SD 34.8) after the last surgery, on average and finishing of 60 therapy sessions (median). First a measurement with the Goettinger Hoarseness Diagram (GHD) was carried out. Next the subjects answered self-reported standardized questionnaires for life quality in oncological patients on the same day: EORTC-QLQ-C30 and 3 scales of the German Fragebogen zur Lebenszufriedenheit (health-related fulfillment, fulfillment with work/occupation, fulfillment with social environment). For disease-related symptoms of different head and neck domains the EORTC-HandN35 was administered.
  
  
  METHODS
  Forty-four patients (37 males, 7 females) who were treated primarily with minimal invasive laser surgery followed by functional voice rehabilitation (Goettinger Konzept). Mean age: 60.1 (SD 9.7) years.
  
  
  RESULTS
  The acoustic voice quality according to the GHD showed a significant correlation with self-reported "Somatic Functioning" (- 0.32, p = 0.04) and "Social Functioning" (- 0.38, p = 0.01) in the EORTC-QLQ-C30 as well as with the symptom scales "Speech" (0.45, p < 0.0024) resp. "Social Contact" (0.45, p = 0.0021) in the EORTC-HandN35. Also hoarseness and health-related fulfillment (- 0.36, p = 0.02) as well as fulfillment with work/occupation (- 0.33, p = 0.03) correlated significantly. On the other hand, there was no significant association between the GHD and the assessment of global quality of life.
  
  
  CONCLUSIONS
  Postoperative phonatory reductions in patients with laser surgically treated laryngeal carcinoma have only a slight influence on overall quality of life. The same is true for the GHD. Assessment of self-reported quality of life in recommendation of oncologic treatment may not be able to replace the objective findings, but may be useful to detect other problems, e.g. psychosocial.
authors.affiliation: Abt. Phoniatrie/Pädaudiologie, Georg-August-Universität Göttingen, Göttingen. silke.ohlwein@med.uni-goettingen.de
authors.forename: S
authors.initials: S
authors.lastname: Ohlwein
authors.forename: E
authors.initials: E
authors.lastname: Kruse
authors.forename: W
authors.initials: W
authors.lastname: Steiner
authors.forename: C
authors.initials: C
authors.lastname: Kiese-Himmel
mesh_terms: D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006685:Hoarseness / Q000175:diagnosis; D006801:Humans; D007822:Laryngeal Neoplasms / Q000534:rehabilitation* / Q000601:surgery*; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D011788:Quality of Life; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D013997:Time Factors; D014831:Voice / Q000502:physiology*; D014833:Voice Quality