title: Monoterpenes from thyme (Thymus vulgaris) as potential mosquito repellents.
abstract: Five monoterpenes (carvacrol, p-cymene, linalool, alpha-terpinene, and thymol) derived from the essential oil of thyme (Thymus vulgaris) were examined for their repellency against the mosquito Culex pipiens pallens. All 5 monoterpenes effectively repelled mosquitoes based on a human forearm bioassay. Alpha-terpinene and carvacrol showed significantly greater repellency than a commercial formulation, N,N-diethyl-m-methylbenzamide (deet), whereas thymol showed similar repellency to that of deet. The duration of repellency after application for all these monoterpenes was equal to or higher than that of deet. These findings indicate that a spray-type solution containing 2% alpha-terpinene may serve as an alternative mosquito repellent.
authors.affiliation: School of Agricultural Biotechnology, Seoul National University, Suwon 441-744, Korea.
authors.forename: Byeoung-Soo
authors.initials: BS
authors.lastname: Park
authors.forename: Won-Sik
authors.initials: WS
authors.lastname: Choi
authors.forename: Jeong-Han
authors.initials: JH
authors.lastname: Kim
authors.forename: Kap-Ho
authors.initials: KH
authors.lastname: Kim
authors.forename: Sung-Eun
authors.initials: SE
authors.lastname: Lee
mesh_terms: D000080462:Acyclic Monoterpenes; D000818:Animals; D003465:Culex; D000081005:Cyclohexane Monoterpenes; D000081007:Cymenes; D003671:DEET; D006801:Humans; D007302:Insect Repellents; D039821:Monoterpenes; D010938:Plant Oils; D013943:Thymol; D046930:Thymus Plant
chemical_list: D000080462:Acyclic Monoterpenes; D000081005:Cyclohexane Monoterpenes; D000081007:Cymenes; D007302:Insect Repellents; D039821:Monoterpenes; D010938:Plant Oils; D003671:DEET; C007210:4-cymene; D013943:Thymol; C018669:gamma-terpinene; C073316:carvacrol; C018584:linalool