title: The pathogenesis of chronic obstructive pulmonary disease: advances in the past 100 years.
authors.affiliation: Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, USA. sshapiro@rics.bwh.Harvard.edu
authors.forename: Steven D
authors.initials: SD
authors.lastname: Shapiro
authors.forename: Edward P
authors.initials: EP
authors.lastname: Ingenito
mesh_terms: D000975:Antioxidants / Q000378:metabolism; D017209:Apoptosis / Q000502:physiology; D005109:Extracellular Matrix / Q000378:metabolism; D006801:Humans; D008168:Lung / Q000378:metabolism / Q000473:pathology; D016877:Oxidants / Q000378:metabolism; D010196:Pancreatic Elastase / Q000378:metabolism; D029424:Pulmonary Disease, Chronic Obstructive / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology*; D012907:Smoking / Q000009:adverse effects
chemical_list: D000975:Antioxidants; D016877:Oxidants; D010196:Pancreatic Elastase