title: Isolated CNS relapse in neuroblastoma.
abstract: We report three patients with primary extracerebral neuroblastoma and central nervous system (CNS) relapse. As the survival of children with metastatic neuroblastoma improves with recent advances in treatment, CNS involvement becomes more frequently detected. MR imaging of the brain and spine are strongly indicated in the follow-up of patients with increased risk of developing CNS disease.
authors.affiliation: Neuroradiology Department, Institut für Neuroradiologie, Klinikum der Johann-Wolfgang-Goethe-Universität, Frankfurt am Main, Germany. luciana.porto@kgu.de
authors.forename: L
authors.initials: L
authors.lastname: Porto
authors.forename: M
authors.initials: M
authors.lastname: Kieslich
authors.forename: B
authors.initials: B
authors.lastname: Yan
authors.forename: D
authors.initials: D
authors.lastname: Schwabe
authors.forename: F E
authors.initials: FE
authors.lastname: Zanella
authors.forename: H
authors.initials: H
authors.lastname: Lanfermann
mesh_terms: D016543:Central Nervous System Neoplasms / Q000473:pathology / Q000556:secondary*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009447:Neuroblastoma / Q000473:pathology*; D012008:Recurrence; D014057:Tomography, X-Ray Computed / Q000379:methods