title: Can the high nuclear to cytoplasmic ratio of human embryonic stem cells make them more vulnerable to physical stress encountered with bulk-passage protocols?
authors.forename: Boon Chin
authors.initials: BC
authors.lastname: Heng
authors.forename: Hua
authors.initials: H
authors.lastname: Liu
authors.forename: Tong
authors.initials: T
authors.lastname: Cao
mesh_terms: D018929:Cell Culture Techniques / Q000379:methods*; D002467:Cell Nucleus / Q000648:ultrastructure*; D002478:Cells, Cultured / Q000166:cytology; D003593:Cytoplasm / Q000648:ultrastructure*; D003599:Cytoskeleton / Q000648:ultrastructure; D004622:Embryo, Mammalian / Q000166:cytology*; D006801:Humans; D013234:Stem Cells / Q000166:cytology*; D013314:Stress, Mechanical