title: [Study on laser flash spectroscopy of laser-induced interaction of DNA and polynucleotides with SO4*-].
abstract: The interactions of DNA and polynucleotides (poly[G],poly[A] and poly[C]) with SO4*- were investigated by 248 nm laser flash photolysis. The results show that, the reactions of poly[G] or poly[A] with SO4*- yield predominantly the corresponding one-electron-oxidated base radicals. With poly[C], it is suggested that SO4*- radical reacts predominantly by addition to the base moiety to produce C5-yl and C6-yl sulphate radical adducts,and subsequently H-abstraction yields C2'-sugar radical. The predominant species resulting from the reaction of DNA with SO4*- is DNA guanyl radical.
authors.affiliation: Department of Chemical Physics, University of Science and Technology of China, 230026 Hefei.
authors.forename: Q
authors.initials: Q
authors.lastname: Song
authors.forename: Q
authors.initials: Q
authors.lastname: LI
authors.forename: Y
authors.initials: Y
authors.lastname: Xu
authors.forename: J
authors.initials: J
authors.lastname: Dai
authors.forename: S
authors.initials: S
authors.lastname: Yu
authors.forename: C
authors.initials: C
authors.lastname: Chen
authors.forename: X
authors.initials: X
authors.lastname: Ma
authors.forename: W
authors.initials: W
authors.lastname: Lin
authors.forename: S
authors.initials: S
authors.lastname: Yao
mesh_terms: D004247:DNA / Q000737:chemistry*; D004249:DNA Damage / Q000528:radiation effects*; D007834:Lasers; D010782:Photolysis / Q000528:radiation effects*; D011119:Polynucleotides / Q000737:chemistry*; D013057:Spectrum Analysis; D013431:Sulfates / Q000737:chemistry*
chemical_list: D011119:Polynucleotides; D013431:Sulfates; C069025:sulfate radical; D004247:DNA