Unusual metastatic spread of follicular thyroid carcinoma: report of a case.
Concurrent skull and liver metastases from follicular thyroid carcinoma is a very rare event. We herein present the case of a 72-year-old woman who initially presented with a swelling in the right supraorbital region that proved to be metastasis from a well-differentiated follicular thyroid carcinoma of clear-cell type. The metastatic workup disclosed a huge liver metastasis and an additional metastasis in the left iliac fossa. The treatment of this patient included a total thyroidectomy, an excision of the skull lesion, and the administration of radioiodine therapy, as well as thyroid-stimulating hormone (TSH) suppression therapy. However, the course of her disease was relentless. Although well-differentiated thyroid carcinoma tends to show an excellent course, the presence of metastatic disease leads to a very dismal prognosis.
Kelessis
Nickos G
NG
First Department of Surgical Oncology, Saint Savvas Anticancer Institute, 171 Alexandra's Ave., 155 22, Athens, Greece.
Prassas
Evangelos P
EP
Evangelos
Prassas P
PP
Dascalopoulou
Dimitra V
DV
Dimitra
Dascalopoulou V
DV
Apostolikas
Nikiforos A
NA
Nikiforos
Apostolikas A
AA
Tavernaraki
Angeliki P
AP
Angeliki
Tavernaraki P
TP
Vassilopoulos P
Pericles P
PP
Pericles
Vassilopoulos P
VP
D018263:Adenocarcinoma, Follicular / Q000556:secondary* / Q000628:therapy; D000368:Aged; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy; D012888:Skull Neoplasms / Q000556:secondary* / Q000628:therapy; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000628:therapy; D013965:Thyroidectomy