title: Technical considerations for implementation of x-ray CT polymer gel dosimetry.
abstract: Gel dosimetry is the most promising 3D dosimetry technique in current radiation therapy practice. X-ray CT has been shown to be a feasible method of reading out polymer gel dosimeters and, with the high accessibility of CT scanners to cancer hospitals, presents an exciting possibility for clinical implementation of gel dosimetry. In this study we report on technical considerations for implementation of x-ray CT polymer gel dosimetry. Specifically phantom design, CT imaging methods, imaging time requirements and gel dose response are investigated. Where possible, recommendations are made for optimizing parameters to enhance system performance. The dose resolution achievable with an optimized system is calculated given voxel size and imaging time constraints. Results are compared with MRI and optical CT polymer gel dosimetry results available in the literature.
authors.affiliation: Medical Physics, BC Cancer Agency-Vancouver Island Centre, Victoria, Canada. mhilts@bccancer.bc.ca
authors.forename: M
authors.initials: M
authors.lastname: Hilts
authors.forename: A
authors.initials: A
authors.lastname: Jirasek
authors.forename: C
authors.initials: C
authors.lastname: Duzenli
mesh_terms: D000180:Acrylic Resins / Q000032:analysis / Q000737:chemistry* / Q000528:radiation effects*; D000465:Algorithms; D004867:Equipment Design; D019544:Equipment Failure Analysis; D017410:Practice Guidelines as Topic; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000295:instrumentation / Q000379:methods*; D011874:Radiometry / Q000295:instrumentation* / Q000379:methods*; D013673:Technology Assessment, Biomedical; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D000180:Acrylic Resins; C016680:polyacrylamide gels