title: Does a second-look operation improve survival in patients with peritonitis due to acute mesenteric ischemia? A five-year retrospective experience.
abstract: Second-look laparotomy is one of the mainstays of surgical treatment of acute mesenteric ischemia (AMI). The aim of this study was to analyze its role in the survival of patients with infarcted gangrenous bowel resulting from AMI. A retrospective chart review of all patients admitted over the study period was undertaken. The study population consisted of 41 patients with clinical evidence of peritonitis and gangrenous, perforated bowel on surgical exploration. Outcome was compared among patients who underwent second-look laparotomy and those who did not. Fifteen patients with an American Society of Anesthesiologists (ASA) score of less than 4 underwent second-look laparotomy. Six patients had residual necrotic bowel that required additional resection. Only one (17%) of them survived. Of the nine remaining patients, who had no evidence of necrosis, only two survived (22%). Overall survival in this group was 20%. Twenty-six patients were managed without second-look laparotomy. Nine of them, with an ASA score of 4-5, died soon after the operation. The decision not to operate on the remaining 17 patients with an ASA score < 4 was made by an experienced surgeon. Eleven of those patients (65%) survived. Overall survival in the non-second-look group was 42%. Excluding the early deaths, the survival in the non re-explored group was significantly higher than in the second-look group (65% vs. 20%, p = 0.011). A selective approach to the surgical treatment of acute mesenteric ischemia based on the sound clinical judgment of an experienced surgeon may be as appropriate as its universal application.
authors.affiliation: Department of Surgery, Rabin Medical Center, Beilinson Campus, 49100, Petah Tiqva, Israel.
authors.forename: Oleg
authors.initials: O
authors.lastname: Kaminsky
authors.forename: Igal
authors.initials: I
authors.lastname: Yampolski
authors.forename: David
authors.initials: D
authors.lastname: Aranovich
authors.forename: Ehud
authors.initials: E
authors.lastname: Gnessin
authors.forename: Franklin
authors.initials: F
authors.lastname: Greif
mesh_terms: D000208:Acute Disease; D015897:Comorbidity; D005260:Female; D006801:Humans; D007813:Laparotomy; D008297:Male; D008641:Mesenteric Vascular Occlusion / Q000150:complications* / Q000601:surgery*; D010538:Peritonitis / Q000209:etiology / Q000401:mortality*; D012189:Retrospective Studies; D024162:Second-Look Surgery; D016896:Treatment Outcome