Dysphagia in aging.
Dysphagia is a common problem in older patients and is becoming a larger health care problem as the populations of the United States and other developed countries rapidly age. Changes in physiology with aging are seen in the upper esophageal sphincter and pharyngeal region in both symptomatic and asymptomatic older individuals. Age related changes in the esophageal body and lower esophageal sphincter are more difficult to identify, while esophageal sensation certainly is blunted with age. Stroke, Parkinson's disease, amyotrophic lateral sclerosis, Zenker's diverticula, and several other motility and structural disorders may cause oropharyngeal dysphagia in an older patient. Esophageal dysphagia can also be caused by both disorders of motility (achalasia, diffuse esophageal spasm, scleroderma and others) and structure (malignancy, strictures, rings, external compression, and others). Many of these disorders have an increased prevalence in older patients and should be sought with an appropriate diagnostic evaluation in older patients. The treatment of dysphagia in older patients is similar to that in younger patients, but more invasive therapies such as surgery may not be possible in some older patients making less aggressive medical and endoscopic therapy more attractive.
Achem
Sami R
SR
Department of Medicine, Mayo Clinic College of Medicine, Jacksonville, FL 32224, USA.
Devault
Kenneth R
KR
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D003680:Deglutition Disorders / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology; D004947:Esophagus / Q000502:physiology; D006801:Humans; D009426:Netherlands / Q000453:epidemiology; D010528:Peristalsis; D015995:Prevalence