title: Gastric adenocarcinoma with leptomeningeal carcinomatosis as the presenting manifestation: an autopsy case report.
abstract: Leptomeningeal carcinomatosis is a clinically important and severe complication in patients with cancer. Leptomeningeal involvement as a secondary event in gastric carcinoma is rarely reported and usually occurs late in advanced disease. Herein, we report a case of leptomeningeal carcinomatosis as the initial manifestation of a previously asymptomatic gastric adenocarcinoma. The clinical features and the appropriate diagnostic procedures are discussed.
authors.affiliation: Institute of Neuropathology, Department of Gastroenterology, Otto-von-Guericke-University, Magdeburg, Germany. s.braeuninger@gmx.net
authors.forename: Stefan
authors.initials: S
authors.lastname: Braeuninger
authors.forename: Christian
authors.initials: C
authors.lastname: Mawrin
authors.forename: Peter
authors.initials: P
authors.lastname: Malfertheiner
authors.forename: Hans-Ulrich
authors.initials: HU
authors.lastname: Schildhaus
authors.forename: Christiane
authors.initials: C
authors.lastname: Seiler
authors.forename: Knut
authors.initials: K
authors.lastname: Dietzmann
authors.forename: Hartmut
authors.initials: H
authors.lastname: Lins
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000556:secondary*; D000368:Aged; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology / Q000556:secondary*; D009382:Neoplasms, Unknown Primary / Q000473:pathology*; D013274:Stomach Neoplasms / Q000473:pathology*