title: Perinuclear translocation of hsp 27 in shear stress exposed human endothelial cells.
abstract: Expression of hsp 27 in human umbilical vein endothelial cells exposed to a shear stress was investigated. Using immunostaining, it was concluded that shear stress results in perinuclear translocation of hsp 27. Polymerization of actin microfilaments plays an important role in this process.
authors.affiliation: Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 305-701, Korea. yoosy@kaist.ac.kr
authors.forename: So Young
authors.initials: SY
authors.lastname: Yoo
authors.forename: Chanil
authors.initials: C
authors.lastname: Chung
authors.forename: Jung Kyung
authors.initials: JK
authors.lastname: Kim
authors.forename: Jun Keun
authors.initials: JK
authors.lastname: Chang
mesh_terms: D008841:Actin Cytoskeleton / Q000378:metabolism; D000199:Actins / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism*; D002478:Cells, Cultured; D042783:Endothelial Cells / Q000378:metabolism; D004730:Endothelium, Vascular / Q000166:cytology / Q000378:metabolism*; D018840:HSP70 Heat-Shock Proteins / Q000378:metabolism*; D006801:Humans; D021381:Protein Transport; D013314:Stress, Mechanical; D014471:Umbilical Veins / Q000166:cytology
chemical_list: D000199:Actins; D018840:HSP70 Heat-Shock Proteins