title: Acetabular augmentation induced by extracorporeal shock waves in rabbits.
abstract: We conducted this animal study to demonstrate whether exposing the acetabulum in immature rabbits to extracorporeal shock waves induces bone formation in the acetabulum. Five thousand shock waves of 100 MPa each were directed, from outside, at the acetabular roof of eight immature rabbits. At each of two time points (4 and 8 weeks) after treatment, the pelvises of four rabbits were removed and evaluated morphologically. Woven bone formation was observed on the lateral margin of the acetabular roof at 4 weeks after treatment, and the breadth of the acetabular roof in the coronal plane was significantly increased. Eight weeks after treatment, the woven bone disappeared; the breadth of the acetabular roof, however, was significantly increased. These findings demonstrated that extracorporeal shock waves induced acetabular augmentation in rabbits. We conclude that extracorporeal shock waves, perhaps, could be applied clinically for the treatment of acetabular dysplasia.
authors.affiliation: Division of Orthopaedic Surgery, Chiba Children's Hospital, Chiba University, Chiba, Japan. h-saisu@dc4.so-net.ne.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Saisu
authors.forename: Makoto
authors.initials: M
authors.lastname: Kamegaya
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Wada
authors.forename: Kenji
authors.initials: K
authors.lastname: Takahashi
authors.forename: Shigeru
authors.initials: S
authors.lastname: Mitsuhashi
authors.forename: Hideshige
authors.initials: H
authors.lastname: Moriya
authors.forename: Markus
authors.initials: M
authors.lastname: Maier
mesh_terms: D000077:Acetabulum / Q000000981:diagnostic imaging / Q000528:radiation effects*; D000818:Animals; D004307:Dose-Response Relationship, Radiation; D019220:High-Energy Shock Waves; D008297:Male; D010012:Osteogenesis / Q000528:radiation effects*; D011817:Rabbits; D011859:Radiography