title: Structure and unique interactions with DNA of a cationic trans-platinum complex with the nonplanar bicyclic piperidinopiperidine ligand.
authors.affiliation: Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.
authors.forename: Yousef
authors.initials: Y
authors.lastname: Najajreh
authors.forename: Dmitri
authors.initials: D
authors.lastname: Prilutski
authors.forename: Yael
authors.initials: Y
authors.lastname: Ardeli-Tzaraf
authors.forename: Jose Manuel
authors.initials: JM
authors.lastname: Perez
authors.forename: Elena
authors.initials: E
authors.lastname: Khazanov
authors.forename: Yechezkel
authors.initials: Y
authors.lastname: Barenholz
authors.forename: Jana
authors.initials: J
authors.lastname: Kasparkova
authors.forename: Viktor
authors.initials: V
authors.lastname: Brabec
authors.forename: Dan
authors.initials: D
authors.lastname: Gibson
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D002945:Cisplatin / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry; D018360:Crystallography, X-Ray; D004247:DNA / Q000737:chemistry*; D018736:DNA Adducts / Q000737:chemistry; D006801:Humans; D020128:Inhibitory Concentration 50; D008024:Ligands; D015394:Molecular Structure; D009944:Organoplatinum Compounds / Q000138:chemical synthesis*; D010880:Piperidines / Q000737:chemistry*; D010984:Platinum / Q000737:chemistry*
chemical_list: C105149:4-(1-piperidino)piperidine; D000970:Antineoplastic Agents; D018736:DNA Adducts; D008024:Ligands; D009944:Organoplatinum Compounds; D010880:Piperidines; D010984:Platinum; D004247:DNA; D002945:Cisplatin