title: [Relation between arterial compliance and the prematurity of reflected wave on pulse pressure curve evaluated by tonometric sphygmography].
abstract: The effect of antihypertensive drugs on the arterial pressure pulse can usually be explained by a change in the timing or intensity of wave reflection or by alteration in the pattern of ventricular ejection. Alteration in timing wave reflection is believed to cause the characteristic changes of pressure wave such: augmentation, augmentation index, "precocity index of second systolic peek" (P2). After calcium channel blockers augmentation decreases from 15 mmHg to 9.4 mmHg, augmentation index P2/P1 (P1 is the first systolic peek) decreases from 132.2 +/- 20% to 129.2 +/- 19.5% and "precocity index of P2" increases from 68.8 +/- 5% ejection duration to 71.8 +/- 4.6% ejection duration.
authors.affiliation: Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină, Clinica a IV-a Medicală-Nefrologie.
authors.forename: O V
authors.initials: OV
authors.lastname: Prisadă
authors.forename: A
authors.initials: A
authors.lastname: Covic
authors.forename: Iulia
authors.initials: I
authors.lastname: Boaru
authors.forename: Nicoleta
authors.initials: N
authors.lastname: Dubei
authors.forename: Camelia
authors.initials: C
authors.lastname: Mutică
authors.forename: G
authors.initials: G
authors.lastname: Ungureanu
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D000959:Antihypertensive Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects*; D003187:Compliance / Q000187:drug effects; D004338:Drug Combinations; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000494:pharmacology; D005996:Nitroglycerin / Q000494:pharmacology; D010991:Plethysmography / Q000295:instrumentation / Q000379:methods; D017534:Radial Artery / Q000503:physiopathology; D014655:Vascular Resistance / Q000187:drug effects; D014665:Vasodilator Agents / Q000494:pharmacology
chemical_list: D000959:Antihypertensive Agents; D004338:Drug Combinations; D014665:Vasodilator Agents; D005996:Nitroglycerin; D009543:Nifedipine