[Observation on therapeutic effect of jianpi huoxue herbs combined with chemotherapy in treating post-operational colonic cancer patients].
OBJECTIVE
To observe and compare the therapeutic effect of Jianpi Huoxue herbs (JPHXH) combined with chemotherapy (CT) in treating post-operational colonic cancer patients with Pi deficiency Syndrome (PDS).


METHODS
Adopting randomized control trial method, 64 patients were divided into two groups. The treated group (n = 43) received JPHXH plus CT and the control group ( n = 21 ) received CT alone. A treatment course of 3 months was applied to both groups. Therapeutic effect, changes of PDS and incidence of adverse reaction in the two groups were observed.


RESULTS
The tumor remission rate in the treated group and the control group was 39.5 % and 33.3 %, respectively. The effective rate on PDS in the treated group and the control group was 72.1% and 19.0%, respectively, showing significant difference (P < 0.01). The incidence of adverse reaction was lower in the treated group than that in the control group (P < 0.05).


CONCLUSIONS
JPHXH is effective in treating post-operational colonic cancer patients with PDS and relieving the adverse reaction of chemotherapy to certain extent.
Liu
Jing
J
Second Department of Oncology, Shanghai Hospital of TCM, Shanghai. angelliujing2004@yahoo.com.cn
Wang
Wei-ping
WP
Zhou
Yi-yang
YY
D000230:Adenocarcinoma / Q000188:drug therapy / Q000601:surgery; D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000601:surgery; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D011184:Postoperative Period
D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal