[Changes of blood-aqueous barrier after phacoemulsification in patients with previous glaucoma filtering surgery].
OBJECTIVE
To evaluate the effect of trabeculectomy and/or phacoemulsification surgery on blood-aqueous barrier function.


METHODS
Phacoemulsification with implantation of intraocular lens was performed on 46 cataract eyes of 40 glaucoma patients following previous trabeculectomy (group 1), and 64 cataract eyes of 60 patients (group 2). The aqueous flare and cells were examined preoperatively and on days 1, 7, 30, 90 postoperatively using a laser flare-cell meter (LFCM).


RESULTS
The mean aqueous flare values were (15.12 +/- 2.87), (40.24 +/- 3.75), (24.33 +/- 3.38), (21.18 +/- 1.77), (16.51 +/- 1.70) photon counts/ms in group 1 preoperatively and on days 1, 7, 30, 90 after surgery (P < 0.05) respectively; and were (6.94 +/- 2.34), (26.27 +/- 10.21), (13.96 +/- 6.44), (9.07 +/- 2.67), (7.16 +/- 1.89) photon counts/ms in group 2 (P < 0.05) respectively.


CONCLUSIONS
Trabeculectomy can breakdown blood-aqueous barrier permanently while phacoemulsification damage the blood-aqueous barrier transiently. Phacoemulsification combined with a previous trabeculectomy can enhance this damage.
Luo
Li-xia
LX
Zhongshan Ophthalmic Center, San Yat-sen University, Guangzhou 510060, China.
Liu
Yi-zhi
YZ
Ge
Jian
J
Zhang
Xin-yu
XY
Liu
Yu-hua
YH
Wu
Ming-xing
MX
D000368:Aged; D000369:Aged, 80 and over; D018916:Blood-Aqueous Barrier / Q000378:metabolism*; D002386:Cataract / Q000378:metabolism*; D005260:Female; D005901:Glaucoma / Q000601:surgery; D006801:Humans; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods*; D014130:Trabeculectomy / Q000009:adverse effects*