Carbohydrate-coated nanocapsules from amphiphilic rod-coil molecule: binding to bacterial type 1 pili.
Stable carbohydrate-coated nanocapsules designed as multivalent nanoscaffolds for selective interactions with receptors are able to encapsulate guest molecules within their interior and to bind efficiently to FimH adhesin of bacterial type 1 pili.
Kim
Byung-Sun
BS
Center for Supramolecular Nano-Assembly and Department of Chemistry, Yonsei University, Shinchon 134, Seoul 120-749, Korea.
Yang
Won-Young
WY
Ryu
Ja-Hyoung
JH
Yoo
Yong-Sik
YS
Lee
Myongsoo
M
D002241:Carbohydrates / Q000737:chemistry*; D004926:Escherichia coli / Q000737:chemistry / Q000648:ultrastructure; D010861:Fimbriae, Bacterial / Q000737:chemistry* / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D053769:Nanocapsules / Q000737:chemistry*
D002241:Carbohydrates; D053769:Nanocapsules