[Wilson's disease: clinical diagnosis and "faces of panda" signs in magnetic resonance imaging. Case report].
A 25 year-old man was admitted with polymorph symptomatology resembling basal ganglia disease associated with psychiatric manifestations. The patient had been treated with pericyazine. The drug was stopped but the symptomatology did not improve. The diagnosis of Wilson's disease was established through ophthalmologic examination with slit-lamp that revealed the Kayser-Fleischer ring and laboratory abnormalities showing a low serum ceruloplasmin level and increased urinary copper excretion. T2-weighted axial magnetic resonance imaging demonstrated the " face of panda signs" in the midbrain and pons.
Brito
José Correia de Farias
JC
Serviço de Neurologia, Hospital Universitário Lauro Wanderley, Universidade Federal da Paraíba, João Pessoa, Brazil.
Coutinho
Mário de Almeida Pereira
Mde A
Almeida
Hermano José Falcone de
HJ
Nóbrega
Paulo Virgolino da
PV
D000328:Adult; D015415:Biomarkers / Q000032:analysis / Q000652:urine; D002570:Ceruloplasmin / Q000032:analysis; D003300:Copper / Q000652:urine; D006527:Hepatolenticular Degeneration / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male
D015415:Biomarkers; D003300:Copper; D002570:Ceruloplasmin