[Investigations of beta-dosimetry at two different sources for the cardiovascular brachytherapy].
The intracoronary brachytherapy is used at the Hamburg University Hospital as a method to treat in-stent restenosis. Two different radiochromic film types were applied to obtain dosimetric information of the beta-sources used (32P and 90Sr/90Y). First, these films were analyzed for their suitability for dosimetry. Within the investigated dose range (MD-55-2: 0 to 33 Gy, HD-810: 0 to 105 Gy), both films showed a linear behavior between the dose and the optical density (OD). Because radiochromic films are subject to time-based changes in OD, a method for colour stabilization was investigated (RCS-method). This method allowed to greatly shorten the time between irradiation and evaluation from 24 hours (time necessary for the film to reach a quasi-stable status) to 2.5 hours. Colour-stabilized films can also be stored for a long time and reanalyzed with almost the same results. Within the limits of the measurements error, both film types showed an energy independent response. Within the dose profiles, analyses of the two source types resulted in differences of 13.5% (32P) and 21% (90Sr/90Y). These inhomogenities are consistent with the fabrication tolerances given by the manufactures.
Todorovic
Manuel
M
Radiologisches Zentrum, Klinik für Strahlentherapie und Radioonkologie, Sektion Medizinische Strahlenphysik, Universitätsklinikum Hamburg-Eppendorf (UKE), Hamburg. todorovic@uke.uni-hamburg.de
Cremers
Florian
F
Thurmann
Horst
H
Schmidt
Rainer
R
D001610:Beta Particles / Q000627:therapeutic use; D001918:Brachytherapy / Q000379:methods*; D003324:Coronary Artery Disease / Q000601:surgery*; D023903:Coronary Restenosis / Q000532:radiotherapy*; D006801:Humans; D011879:Radiotherapy Dosage; D015607:Stents