Cellular telephones and risk for brain tumors: a population-based, incident case-control study.
OBJECTIVE
To evaluate a possible association of glioma or meningioma with use of cellular telephones, using a nationwide population-based case-control study of incident cases of meningioma and glioma.


METHODS
The authors ascertained all incident cases of glioma and meningioma diagnosed in Denmark between September 1, 2000, and August 31, 2002. They enrolled 252 persons with glioma and 175 persons with meningioma aged 20 to 69. The authors also enrolled 822 randomly sampled, population-based controls matched for age and sex. Information was obtained from personal interviews, medical records containing diagnoses, and the results of radiologic examinations. For a small number of cases and controls, the authors obtained the numbers of incoming and outgoing calls. They evaluated the memory of the respondents with the Mini-Mental State Examination and obtained data on socioeconomic factors from Statistics Denmark.


RESULTS
There were no material socioeconomic differences between cases and controls or participants and non-participants. Use of cellular telephone was associated with a low risk for high-grade glioma (OR, 0.58; 95% CI, 0.37 to 0.90). The risk estimates were closer to unity for low-grade glioma (1.08; 0.58 to 2.00) and meningioma (1.00; 0.54 to 1.28).


CONCLUSIONS
The results do not support an association between use of cellular telephones and risk for glioma or meningioma.
Christensen
H Collatz
HC
Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark. hcollatz@dadlnet.dk
Schüz
J
J
Kosteljanetz
M
M
Poulsen
H Skovgaard
HS
Boice
J D
JD
McLaughlin
J K
JK
Johansen
C
C
D000328:Adult; D017677:Age Distribution; D000368:Aged; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology*; D016022:Case-Control Studies; D015984:Causality; D040421:Cell Phone / Q000706:statistics & numerical data*; D015331:Cohort Studies; D003718:Denmark / Q000453:epidemiology; D004574:Electromagnetic Fields / Q000009:adverse effects; D005260:Female; D005910:Glioma / Q000000981:diagnostic imaging / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology*; D008579:Meningioma / Q000000981:diagnostic imaging / Q000453:epidemiology*; D008875:Middle Aged; D016017:Odds Ratio; D011859:Radiography; D012307:Risk Factors; D017678:Sex Distribution; D012923:Social Class