title: Splenic malignancy: a minimally invasive approach.
abstract: Since the advent of laparoscopy and its general acceptance for treating benign diseases, indications for malignant disease have been investigated. Recently, greater evidence shows that laparoscopy for malignant disease is oncologically safe.
  
  
  METHODS
  We review a minimally invasive approach to splenic malignancy and the common malignant diseases involving the spleen. We outline our preferred technique for splenectomy in detail. Additionally, the recent literature is reviewed regarding outcome after laparoscopic splenectomy for benign and malignant disease. The data from three studies, containing a total of 327 were analyzed. Complication rates, mortality, and length of stay were compared.
  
  
  RESULTS
  There was no statistically significant difference identified between those undergoing laparoscopic splenectomy for benign versus malignant disease in terms of length of stay, complication rate or mortality. There were significant differences between the two groups in terms of operative time and spleen weight.
  
  
  CONCLUSIONS
  In open splenectomy series for patients with malignant diseases of the spleen, complication and mortality are much higher when compared to those patients undergoing open splenectomy for benign disease. The discussed series show no difference in endpoints when laparoscopy is used. Laparoscopic splenectomy for malignant disease confers significant benefit and rapid recovery for an otherwise at risk population.
authors.affiliation: Department of Minimally Invasive Surgery, Cedars Sinai Medical Center, Los Angeles, California 90048, USA.
authors.forename: Miguel
authors.initials: M
authors.lastname: Burch
authors.forename: Monali
authors.initials: M
authors.lastname: Misra
authors.forename: Edward H
authors.initials: EH
authors.lastname: Phillips
mesh_terms: D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008223:Lymphoma / Q000601:surgery*; D011183:Postoperative Complications; D013156:Splenectomy / Q000379:methods*; D013160:Splenic Neoplasms / Q000601:surgery*; D016896:Treatment Outcome