title: [Qualitative determination of flavonoids and phenol-carboxylic acids of indigene Stachys species using HPLC method].
abstract: Indigene Stachys species have a high content in interesting compounds as iridoids, but also high quantities of flavonoids and phenol-carboxylic acids. These compounds present vasorelaxing effect on smooth vascular muscle interfering with metabolic degradation of nitric oxide pathways (inhibition of peroxynitrites formation) and by inhibition of phosphodiesterase. This work shows flavonoids spectrum of 3 Stachys species using HPLC methods. We identified quercetol, rutoside, miricetin and phenol-carboxylic acids (chlorogenic, caffeic and ferulic acids).
authors.affiliation: Universitatea de Medicină şi Farmacie Târgu-Mureş, Facultatea de Farmacie, Disciplina de Controlul medicamentelor.
authors.forename: Daniela
authors.initials: D
authors.lastname: Muntean
authors.forename: C E
authors.initials: CE
authors.lastname: Vari
authors.forename: Silvia
authors.initials: S
authors.lastname: Imre
authors.forename: Maria T
authors.initials: MT
authors.lastname: Dogaru
mesh_terms: D002264:Carboxylic Acids / Q000032:analysis* / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D005419:Flavonoids / Q000032:analysis* / Q000494:pharmacology; D062385:Hydroxybenzoates / Q000032:analysis* / Q000494:pharmacology; D009131:Muscle, Smooth, Vascular / Q000187:drug effects; D010936:Plant Extracts; D012383:Romania; D031366:Stachys / Q000737:chemistry*
chemical_list: D002264:Carboxylic Acids; D005419:Flavonoids; D062385:Hydroxybenzoates; D010936:Plant Extracts