title: [Micro-CT analysis of cancellous bone fragments from the distal radius fracture zone in osteoporosis].
abstract: The incidence and prevalence of osteoporosis must be considered to continue to increase significantly due to the expected demographic development and environmental changes. In the diagnosis and staging of osteoporosis the three-dimensional bone structure should be as important as the bone mass or the mineral content of the bone. In this study, microfragments were taken from distal radius fracture zones and investigated in Micro-CT scans. Patients in which osteodensitometry of the lumbal spine had revealed osteoporosis in were found to have significantly reduced bone mass, bone density and trabecular thickness. Trabecular fractures which were found in non-osteoporotic patients even in robust trabeculae were detected by the two-dimensional analysis in thin locations and arborizations. Despite some trabeculae turned out to be very small the differences in the histomorphometry and the quality of trabecular fractures in osteoporotic as well as non-osteoporotic patients could be visualized very good in the Micro-CT analysis.
authors.affiliation: Klinik und Poliklinik für Unfallchirurgie, Justus-Liebig-Universität Giessen, Rudolf-Buchheim-Strasse 7, 35385 Giessen. christian.heiss@chiru.med.uni-giessen.de
authors.forename: C
authors.initials: C
authors.lastname: Heiss
authors.forename: S A
authors.initials: SA
authors.lastname: Meissner
authors.forename: A
authors.initials: A
authors.lastname: Mohr
authors.forename: H D
authors.initials: HD
authors.lastname: Litzlbauer
authors.forename: C
authors.initials: C
authors.lastname: Meyer
authors.forename: R
authors.initials: R
authors.lastname: Schnettler
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011856:Radiographic Image Enhancement / Q000379:methods*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D011885:Radius Fractures / Q000000981:diagnostic imaging* / Q000209:etiology / Q000503:physiopathology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity