title: Differences of perioperative liver function, transfusion, and complications according to the type of hepatectomy in living donors.
abstract: Numerous living donor hepatectomy are being performed safely. However, donors are still exposed to various complications including hepatic failure. We examined the donor's potential risk and morbidity depending on the type of hepatectomy: left lateral segmentectomy (group LLS, n = 30), left lobectomy (group LL, n = 15), and right lobectomy (group RL, n = 128). The charts and computerized hospital data of 173 donors from March 2000 to September 2003 were retrospectively reviewed. We analyzed liver function tests (LFT), RBC transfusion, and complications. Although the graft weight was greatest, and surgical and anesthetic times were longest in the group RL, there were no significant differences in postoperative hospital stay, RBC transfusion, and major complications among the groups. However, minor complications were significantly higher in group RL than group LLS. Postoperative prothrombin time and total bilirubin were significantly higher in the group RL than the other groups (P < 0.05). Living donor hepatectomy is relatively safe, and it is evidenced by rapid recovery of LFT and low occurrence of major complications. However, noticeable depression of LFT and frequent minor complications occur after hepatectomy, especially RL.
authors.affiliation: Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Ilwon-dong, Kangnam-ku, Seoul, Korea.
authors.forename: Soo Joo
authors.initials: SJ
authors.lastname: Choi
authors.forename: Mi Sook
authors.initials: MS
authors.lastname: Gwak
authors.forename: Myung Hee
authors.initials: MH
authors.lastname: Kim
authors.forename: Mikyung
authors.initials: M
authors.lastname: Yang
authors.forename: Justin Sang
authors.initials: JS
authors.lastname: Ko
authors.forename: Tae Soo
authors.initials: TS
authors.lastname: Hahm
authors.forename: Gaab Soo
authors.initials: GS
authors.lastname: Kim
mesh_terms: D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D017707:Erythrocyte Transfusion; D005260:Female; D006498:Hepatectomy / Q000009:adverse effects* / Q000379:methods*; D006801:Humans; D008099:Liver / Q000502:physiology; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D011517:Prothrombin Time; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D001663:Bilirubin