title: New fiber configuration for intravenous gas exchange.
abstract: Implantation of a membrane oxygenator (IO) into the vena cava for blood oxygenation in patients with acute lung failure has been researched for the last 25 years. Compared to the extra corporeal blood oxygenation, where blood is handled outside the body, IO doesn't present tubes, housings or heat exchangers, thus reducing considerably blood contact surface and setting priming volume to zero. Otherwise, restricted space in the vena cava and unadvantageous blood flow conditions represent so far a limitation for sufficient gas exchange. A new fiber configuration for intravenous use is being developed, which increases the implantable fiber surface and enhances gas exchange due to the increased blood convection. This is made possible by new fiber bundles, which are free to slide on a catheter and after implantation assume a twisted shape characterized by high homogeneity and fiber density.
authors.affiliation: Helmholtz-Institute for Biomedical Technologies at the RWTH Aachen, Aachen, Germany. cattaneo@hia.rwth-aachen.de
authors.forename: G F
authors.initials: GF
authors.lastname: Cattaneo
authors.forename: H
authors.initials: H
authors.lastname: Reul
mesh_terms: D001187:Artificial Organs; D006801:Humans; D008168:Lung; D010100:Oxygen / Q000097:blood*; D010107:Oxygenators, Membrane; D019736:Prostheses and Implants; D011659:Pulmonary Gas Exchange; D014682:Vena Cava, Inferior
chemical_list: D010100:Oxygen