title: Aging process of myelinated nerve fibers in the human Lissauer tract.
abstract: We calculated numbers and axonal areas of myelinated nerve fibers in the Lissauer tract of the human lumbar spinal cord (L1) from the viewpoint of the aging process. We examined 20 human spinal cords from 13 males and 7 females, age ranging from 41 to 88 years old. We found that, although the number of nerve fibers showed no significant change in relation to the age of the subject, the axonal area of myelinated nerve fiber in the Lissauer tract did decrease with age.
authors.affiliation: Department of Anatomy, Showa University School of Medicine, 5-8, Hatanodai 1, Shinagawa-Ku, Tokyo 142-8555, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Motoura
authors.forename: Noboru
authors.initials: N
authors.lastname: Goto
authors.forename: Jun
authors.initials: J
authors.lastname: Goto
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Ezure
authors.forename: Masakazu
authors.initials: M
authors.lastname: Shibata
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D001369:Axons / Q000502:physiology / Q000648:ultrastructure*; D002452:Cell Count; D048429:Cell Size; D005260:Female; D006801:Humans; D019044:Image Cytometry / Q000295:instrumentation / Q000379:methods; D008161:Lumbosacral Region; D008297:Male; D008853:Microscopy / Q000295:instrumentation / Q000379:methods; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000502:physiology / Q000648:ultrastructure*; D009434:Neural Pathways / Q000166:cytology* / Q000502:physiology; D020671:Posterior Horn Cells / Q000502:physiology / Q000648:ultrastructure; D013116:Spinal Cord / Q000166:cytology* / Q000502:physiology; D013126:Spinal Nerve Roots / Q000502:physiology / Q000648:ultrastructure