Expression and regulation of thrombospondin-1 by human endometrial stromal cells.
Thrombospondin-1 (TSP-1) production was modulated by EGF, IFN-gamma, and in vitro decidualization. It is suggested that TSP-1 may contribute to the regulation of neovascularization in the endometrium and gestational tissues.
Kawano
Yasushi
Y
Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Idaigaoka 1-1, Hasama, Oita 879-5593, Japan. kawayas@med.oita-u.ac.jp
Nakamura
Satomi
S
Nasu
Kaei
K
Fukuda
Junichiro
J
Narahara
Hisashi
H
Miyakawa
Isao
I
D002478:Cells, Cultured; D004717:Endometrium / Q000166:cytology / Q000502:physiology*; D004815:Epidermal Growth Factor / Q000378:metabolism; D005260:Female; D015870:Gene Expression / Q000502:physiology; D006801:Humans; D007371:Interferon-gamma / Q000378:metabolism; D018919:Neovascularization, Physiologic / Q000502:physiology; D012333:RNA, Messenger / Q000032:analysis; D017154:Stromal Cells / Q000166:cytology / Q000502:physiology*; D019700:Thrombospondin 1 / Q000235:genetics* / Q000378:metabolism*
D012333:RNA, Messenger; D019700:Thrombospondin 1; D004815:Epidermal Growth Factor; D007371:Interferon-gamma