title: [Evaluation of macula in patients with branch retinal vein occlusion using multifocal electroretinogram and optical coherence tomography].
abstract: OBJECTIVE
  To evaluate the functions of the macular area in patients with branch retinal vein occlusion (BRVO) by using multifocal electroretinograms (mERG) and optical coherence tomography(OCT).
  
  
  METHODS
  mERGs were recorded from 18 eyes of 18 patients with BRVO. An array of 103 hexagonal elements was displayed on a monitor. The latency (ms) and response density (nV/deg2) of mERGs were measured for 7 central locations. The peak and troughs were labeled N1, P1 and N2, respectively. OCT was used to measure the foveal retinal thickness.
  
  
  RESULTS
  Statistically significant correlation was found between visual acuity(log MAR) and P1-N1 response density (r = - 0.629, p < 0.05) and N2 latency(r = 0.619, p < 0.05). Foveal retinal thickness had the significant statistic correlations with P1-N1 response density (r = -0.750, p < 0.0001), P1-N2 response density (r = -0.520, p < 0.05) and N2 latency (r = 0.488, p < 0.05).
  
  
  CONCLUSIONS
  In 18 BRVO patients, mERGs from the central retinal area were significantly correlated with foveal retinal thickness measured by OCT and with visual acuity. The mERG recording is sensitive to morphological changes and functional disorders induced by BRVO.
authors.affiliation: Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Ikeda
authors.forename: Shigeru
authors.initials: S
authors.lastname: Hasegawa
authors.forename: Keiko
authors.initials: K
authors.lastname: Suzuki
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Usui
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Tanimoto
authors.forename: Mineo
authors.initials: M
authors.lastname: Takagi
authors.forename: Haruki
authors.initials: H
authors.lastname: Abe
authors.forename: Tadayoshi
authors.initials: T
authors.lastname: Kaiya
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004596:Electroretinography; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000473:pathology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012170:Retinal Vein Occlusion / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology*; D041623:Tomography, Optical Coherence; D014785:Vision, Ocular / Q000502:physiology