title: [Protection of puerarin on the cerebral injury in the rats with acute local ischemia].
abstract: OBJECTIVE
  To study the protection of puerarin on the cerebral injury in the rats with acute local ischemia.
  
  
  METHODS
  Rat was evaluated model of acute local cerebral ischemia was made by ligating middle cerebral artery. The cerebral damage toxylin and eosin((HE).
  
  
  RESULTS
  The number of died neurons were significantly less in puerarin-treated rats than in the rats with cerebral ischemia (P < 0. 05). Similarly, the cerebral edema were significantly attenuated in the puerarin-treated rats as compared with cerebrally ischemic rats.
  
  
  CONCLUSIONS
  Puerarin can prevent the neuron from damage induced by acute cerebral ischemia.
authors.affiliation: People's Hospital of Guangxi Autonomous Region, Nanning 530021, China. php1968@126.com
authors.forename: Hong-Ping
authors.initials: HP
authors.lastname: Pan
authors.forename: Jia-Zhen
authors.initials: JZ
authors.lastname: Yang
authors.forename: Xiang-Lan
authors.initials: XL
authors.lastname: Mo
authors.forename: Lu-Li
authors.initials: LL
authors.lastname: Li
authors.forename: Zhen-Lu
authors.initials: ZL
authors.lastname: Huang
authors.forename: Jing
authors.initials: J
authors.lastname: Ye
authors.forename: Jin
authors.initials: J
authors.lastname: Huang
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000473:pathology*; D016923:Cell Death / Q000187:drug effects; D002540:Cerebral Cortex / Q000473:pathology*; D005260:Female; D020244:Infarction, Middle Cerebral Artery / Q000473:pathology; D007529:Isoflavones / Q000494:pharmacology*; D008297:Male; D009474:Neurons / Q000187:drug effects; D018696:Neuroprotective Agents / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D014665:Vasodilator Agents / Q000494:pharmacology
chemical_list: D007529:Isoflavones; D018696:Neuroprotective Agents; D014665:Vasodilator Agents; C033607:puerarin