title: [Results of open radical nephrectomy in a series of 230 patients].
abstract: OBJECTIVE
  To analyse the oncological results of open radical nephrectomy for renal cancer
  
  
  METHODS
  Between December 1989 and June 2003, open radical nephrectomy for renal cancer was performed by the same operator in 230 patients. Cancers treated by partial nephrectomy were excluded from this study. The operation was performed via a lumbar incision in 95.7% of cases. Surveillance consisted of clinical examination and thoracic and abdominopelvic computed tomography twice a year for the first two years, then annually for 3 years, and then at 7 years and at 10 years in the absence of recurrence.
  
  
  RESULTS
  With a median follow-up of 63.1 months, the 5-year and 10-year recurrence-free survival rates were 88.4% and 67.2%, respectively. Tumour size, tumour stage (TNM 1997), Fuhrman's nuclear grade, histological type of cancer, and the presence of suggestive signs were correlated with the recurrence-free survival rate. The 10-year recurrence-free survival rate was zero in patients with visceral or lymph node metastases at the time of diagnosis. The patient's age at the time of diagnosis and the presence of a paraneoplastic syndrome did not influence recurrence free survival in this series.
  
  
  CONCLUSIONS
  This study confirms the data of the literature: tumour size, tumour stage, nuclear grade, histological type, and suggestive signs are prognostic factors of renal cancer. Radical nephrectomy ensures a global 5-year recurrence-free survival rate higher than 85%.
authors.affiliation: Service d'Urologie, Hôpital Cochin, Paris, France. michael.peyromaure@cch.ap-hop-paris.fr
authors.forename: Michaël
authors.initials: M
authors.lastname: Peyromaure
authors.forename: Nicolas
authors.initials: N
authors.lastname: Barry Delongchamps
authors.forename: Fabio
authors.initials: F
authors.lastname: Roffi
authors.forename: Bernard
authors.initials: B
authors.lastname: Debré
authors.forename: Marc
authors.initials: M
authors.lastname: Zerbib
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D011379:Prognosis; D015996:Survival Rate