title: Early versus delayed surgical treatment of open tibial fractures: effect on the rates of infection and need of secondary surgical procedures to promote bone union.
abstract: The purpose of this study was to evaluate whether there was any significant difference in the rates of infection and of secondary surgical procedures to promote bone union, between early(6 h or less after arrival to hospital) and delayed(more than 6 h) surgical treatment of open tibial fractures. Three hundred and eighty-three open tibial fractures were evaluated. 184 fractures had early and 199 had delayed surgical treatment. The rates of infection and secondary surgical procedures to promote bone union of the two groups were compared with univariate and multivariate statistical methods. There was no statistically significant difference between early and delayed treatment groups with respect to overall infection (53/184 versus 51/199 infection rates, P = 0.96), deep infection (8/184 versus 8/199 infection rates, P = 1.0), and rates of secondary surgical procedures to promote bone union (24/184 versus 20/198, P = 0.77). We were unable to demonstrate any significant difference in infection rates or need of secondary procedures to promote bone union, between early and delayed surgical treatment of open tibial fractures.
authors.affiliation: Department of Trauma and Orthopaedics, Manchester Royal Infirmary, Manchester, UK. bcharalambous@hotmail.com
authors.forename: C P
authors.initials: CP
authors.lastname: Charalambous
authors.forename: I
authors.initials: I
authors.lastname: Siddique
authors.forename: M
authors.initials: M
authors.lastname: Zenios
authors.forename: S
authors.initials: S
authors.lastname: Roberts
authors.forename: R
authors.initials: R
authors.lastname: Samarji
authors.forename: A
authors.initials: A
authors.lastname: Paul
authors.forename: P
authors.initials: P
authors.lastname: Hirst
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D005594:Fracture Fixation, Intramedullary / Q000379:methods*; D005597:Fractures, Open / Q000601:surgery*; D005599:Fractures, Ununited / Q000601:surgery; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012086:Reoperation; D012189:Retrospective Studies; D013530:Surgical Wound Infection / Q000209:etiology*; D013978:Tibial Fractures / Q000601:surgery*; D013997:Time Factors