Aziridines versus vinyl carbamates from the direct amination of electron-withdrawing group-substituted trifluoromethyl enoates.
Aza-MIRC (Michael-initiated ring closure) and C-H insertion products were obtained in the reactions of trifluoromethylated olefins with different nosyloxycarbamates by changing base and solvent. Aza-Michael addition products were not isolated. The presence and the position of the trifluoromethyl group allow control of the outcome of the reactions.
Fioravanti
Stefania
S
Dipartimento di Chimica, Università degli Studi La Sapienza, Piazzale Aldo Moro 2, I-00185 Rome, Italy.
Colantoni
Daniele
D
Pellacani
Lucio
L
Tardella
Paolo A
PA