title: Tuberculosis post-liver transplantation: a rare but complicated disease.
abstract: BACKGROUND
  Tuberculosis is a rare but serious complication after transplantation. We report a case and discuss its presentation and management.
  
  
  METHODS
  A 60-year-old Indonesian male presented initially with fever, acute confusion and rapidly progressive right upper lobe pneumonia 3.5 months post-liver transplant, and was diagnosed with pulmonary tuberculosis by positive sputum smear for acid-fast bacilli and tuberculosis culture.
  
  
  RESULTS
  Standard anti-tuberculosis therapy was administered but was complicated by interaction with cyclosporine and drug-induced cholestasis.
  
  
  CONCLUSIONS
  A high level of suspicion, prompt antituberculosis treatment and close follow-up are essential in management of post-transplant tuberculosis.
authors.affiliation: Liver Transplant Programme, National University Hospital, Singapore.
authors.forename: W
authors.initials: W
authors.lastname: Lu
authors.forename: C T
authors.initials: CT
authors.lastname: Wai
authors.forename: M
authors.initials: M
authors.lastname: Da Costa
authors.forename: P A
authors.initials: PA
authors.lastname: Tambyah
authors.forename: K
authors.initials: K
authors.lastname: Prabhakaran
authors.forename: K H
authors.initials: KH
authors.lastname: Lee
mesh_terms: D000904:Antibiotics, Antitubercular / Q000494:pharmacology; D016572:Cyclosporine / Q000008:administration & dosage / Q000097:blood; D004347:Drug Interactions; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000097:blood; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012293:Rifampin / Q000494:pharmacology; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000209:etiology*
chemical_list: D000904:Antibiotics, Antitubercular; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D012293:Rifampin