title: Hepatic vein Doppler waveform in patients with diffuse fatty infiltration of the liver.
abstract: OBJECTIVE
  To determine the incidence of abnormal hepatic vein Doppler waveform in patients with diffuse fatty infiltration of the liver (FIL).
  
  
  METHODS
  In this prospective study, 40 patients with diffuse FIL and 50 normal healthy adults who served as control group underwent hepatic vein (HV) Doppler ultrasonography. The patients with the diagnosis of FIL were 23 men (57.5%) and 17 women aged 30-62 years (mean age +/- S.D., 42 +/- 12 years). Subjects in the control group were 27 men (54%) and 23 women aged 34-65 years (mean age +/- S.D., 45 +/- 14 years). The diagnosis of FIL was confirmed with computed tomography density measurements. The waveforms of HV were classified into three groups: regular triphasic waveform, biphasic waveform without a reverse flow, and monophasic or flat waveform. Etiological factors for FIL were diabetes mellitus (DM), hyperlipidemia and obesity (body mass index > 25). Serum lipid profile was obtained from all the patients with FIL.
  
  
  RESULTS
  Seventeen of the 40 patients (43%) with FIL had an abnormal HV Doppler waveform, whereas only one of the 50 (2%) healthy subjects had an abnormal waveform. The difference in the distribution of normal Doppler waveform pattern between the patients and the control group was significant (P < 0.001). No differences were found in the behaviour of the hepatic vein Doppler waveform in relation to the different etiologic factors for FIL (P > 0.05). There was not any correlation between the degree of fat infiltration and the hepatic vein waveform pattern (P = 0.60).
  
  
  CONCLUSIONS
  Patients with fatty liver has a high rate of an abnormal hepatic vein Doppler waveform pattern which can be biphasic or monophasic. We could not find a relation between the etiological factors for FIL and the occurrence of an abnormal HV Doppler waveform.
authors.affiliation: Department of Radiology, Adana Teaching and Medical Research Center, Baskent University, Adana 01250, Turkey. loguzkurt@yahoo.com
authors.forename: Levent
authors.initials: L
authors.lastname: Oguzkurt
authors.forename: Tulin
authors.initials: T
authors.lastname: Yildirim
authors.forename: Dilek
authors.initials: D
authors.lastname: Torun
authors.forename: Fahri
authors.initials: F
authors.lastname: Tercan
authors.forename: Osman
authors.initials: O
authors.lastname: Kizilkilic
authors.forename: E Alp
authors.initials: EA
authors.lastname: Niron
mesh_terms: D000328:Adult; D000368:Aged; D004562:Electrocardiography / Q000379:methods; D005234:Fatty Liver / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006503:Hepatic Veins / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D011446:Prospective Studies; D012016:Reference Values; D012307:Risk Factors; D014057:Tomography, X-Ray Computed / Q000379:methods; D018616:Ultrasonography, Doppler, Duplex / Q000379:methods*