title: Management of intracorneal bleb after trabeculectomy for congenital glaucoma.
abstract: OBJECTIVE
  Congenital glaucoma is a well-recognized entity that can occur in the presence of anterior segment dysgenesis. Trabeculectomy is an accepted intervention in the management of congenital glaucoma. The surgical technique as well as complications is well described.
  
  
  METHODS
  This is a case report of a 3-month-old girl with anterior segment dysgenesis and glaucoma. She was referred post-trabeculectomy with persistent corneal opacity to be considered for penetrating keratoplasty and was found to have intrastromal corneal bleb.
  
  
  RESULTS
  Ultrasound biomicroscopy confirmed communication of the corneal bleb with the anterior chamber, and the bleb was treated by autologous blood injection at the trabeculectomy site, under acetazolamide cover.
  
  
  CONCLUSIONS
  We present evidence suggesting that abnormal structure was the etiologic basis for corneal bleb formation and describe our management of this previously unreported complication of trabeculectomy.
authors.affiliation: Great Ormond Street Hospital, London, UK.
authors.forename: K K
authors.initials: KK
authors.lastname: Dansingani
authors.forename: A
authors.initials: A
authors.lastname: Al-Khaier
authors.forename: I M
authors.initials: IM
authors.lastname: Russell-Eggitt
authors.forename: K K
authors.initials: KK
authors.lastname: Nischal
mesh_terms: D000086:Acetazolamide / Q000008:administration & dosage* / Q000627:therapeutic use; D000284:Administration, Oral; D000869:Anterior Eye Segment / Q000002:abnormalities; D001768:Blister / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D001769:Blood; D003316:Corneal Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D005260:Female; D005901:Glaucoma / Q000150:complications / Q000151:congenital / Q000601:surgery*; D006801:Humans; D007223:Infant; D015552:Injections, Intralesional; D014130:Trabeculectomy / Q000009:adverse effects*; D014463:Ultrasonography
chemical_list: D000086:Acetazolamide