Yersinia enterocolitica infection in a patient with hemachromatosis masquerading as proximal colon cancer with liver metastases: report of a case.
A patient with genetic hemachromatosis presented with a clinical picture suggesting malignancy and CT evidence of lesions in the right colon and liver. Colonoscopy failed to confirm the suspected diagnosis. Blood and stool cultures were positive for yersinia enterocolittica infection. This case illustrates the need to confirm clinically and radiologically suspected malignancy. It also serves as a model of how localized gastrointestinal pathology can result from the interaction of host genetic factors and specific microbial species.
Crosbie
James
J
Department of Gastroenterology and Colorectal Surgery, University of Newcastle upon Tyne, Royal Victoria Infirmary NE1 4LP, Newcastle upon Tyne, United Kingdom.
Varma
Jag
J
Mansfield
John
J
D003108:Colonic Diseases / Q000000981:diagnostic imaging / Q000382:microbiology*; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D006432:Hemochromatosis / Q000150:complications*; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D015009:Yersinia Infections / Q000175:diagnosis* / Q000000981:diagnostic imaging; D015008:Yersinia enterocolitica / Q000302:isolation & purification*