title: The relationship between left ventricular geometric remodeling and cardiac function in essential hypertension.
abstract: BACKGROUND
  Abnormal left ventricular (LV) diastolic relaxation is an early sign of hypertensive heart disease. Whether diastolic dysfunction differs between LV geometric patterns remains controversial.
  
  
  RESULTS
  We examined 220 hypertensive patients by echocardiography to assess the relationship between diastolic function and LV geometric pattern. We identified four LV geometric patterns: normal geometry, concentric remodeling, concentric hypertrophy, and eccentric hypertrophy. Diastolic function was evaluated by the E/A ratio, E wave deceleration time (Dct), and isovolumic relaxation time (IRT). The E/A ratio was below one and Dct was prolonged in each group. The duration of IRT in the concentric and eccentric hypertrophy groups was significantly longer than that in normal geometry and concentric remodeling groups (p < 0.05).
  
  
  CONCLUSIONS
  Hypertensive patients may be possible to have diastolic dysfunction, regardless of the differences in their structural geometry. The degree of impairment of cardiac diastolic function differed between hypertensive patients with different LV geometric patterns.
authors.affiliation: Asakayama General Hospital, Japan.
authors.forename: Shigeya
authors.initials: S
authors.lastname: Oda
authors.forename: Minoru
authors.initials: M
authors.lastname: Yoshiyama
authors.forename: Naoya
authors.initials: N
authors.lastname: Ichiba
authors.forename: Toru
authors.initials: T
authors.lastname: Kataoka
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Takemoto
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hozumi
authors.forename: Kazuhide
authors.initials: K
authors.lastname: Takeuchi
authors.forename: Junichi
authors.initials: J
authors.lastname: Yoshikawa
mesh_terms: D000368:Aged; D004452:Echocardiography; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D020257:Ventricular Remodeling