Milkers' nodules complicated by erythema multiforme and graft-versus-host disease after allogeneic hematopoietic stem cell transplantation for multiple myeloma.
We describe a case of cow-transmitted parapoxvirus infection--also known as milkers' nodules--after a hematopoietic stem cell transplantation for multiple myeloma. The infection was complicated by erythema multiforme and acute exacerbation of graft-versus-host disease. Parapoxvirus was confirmed by electron microscopy. The natural history of milker's nodules in immunocompetent hosts is described and compared to that in our immunocompromised patient.
Slattery
Wendolyn R
WR
Section of Infectious Diseases, Department of Medicine, University of Wisconsin, Madison, Wisconsin 53706, USA.
Juckett
Mark
M
Agger
William A
WA
Radi
Craig A
CA
Mitchell
Teri
T
Striker
Rob
R
D000328:Adult; D004892:Erythema Multiforme / Q000150:complications*; D006086:Graft vs Host Disease / Q000150:complications* / Q000188:drug therapy; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D009101:Multiple Myeloma / Q000628:therapy*; D011213:Poxviridae Infections / Q000150:complications* / Q000473:pathology
D007166:Immunosuppressive Agents