title: Comparison of trend detection algorithms in the analysis of physiological time-series data.
abstract: This paper presents a comparative performance analysis of various trend detection methods developed using fuzzy logic, statistical, regression, and wavelet techniques. The main contribution of this paper is the introduction of a new method that uses noise rejection fuzzy clustering to enhance the performance of trend detection methodologies. Furthermore, another contribution of this work is a comparative investigation that produced systematic guidelines for the selection of a proper trend detection method for different application requirements. Examples of representative physiological variables considered in this paper to examine the trend detection algorithms are: 1) blood pressure signals (diastolic and systolic); and 2) heartbeat rate based on RR intervals of electrocardiography signal. Furthermore, synthetic physiological data intentionally contaminated with various types of real-life noise has been generated and used to test the performance of trend detection methods and develop noise-insensitive trend-detection algorithms.
authors.affiliation: Department of Mechanical Engineering, University of Waterloo, ON N2L 3G1, Canada. wael.melek@utoronto.ca
authors.forename: William W
authors.initials: WW
authors.lastname: Melek
authors.forename: Ziren
authors.initials: Z
authors.lastname: Lu
authors.forename: Alex
authors.initials: A
authors.lastname: Kapps
authors.forename: William D
authors.initials: WD
authors.lastname: Fraser
mesh_terms: D000465:Algorithms; D001683:Biological Clocks / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D017143:Fuzzy Logic; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D012044:Regression Analysis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D013997:Time Factors