Recent findings on the genetic basis of bipolar disorder.
What began as a search for a specific gene for bipolar disorder has now become a search for multiple susceptibility genes as it has be-come clear that the genetic basis of bipolar disorder probably involves multiple genes interacting with each other and with environmental components in as-yet mysterious ways. This article reviews the most recent findings and the emerging picture in the genetics of bipolar disorder.
Payne
Jennifer L
JL
Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, 600 North Wolfe Street, Meyer 3-181, Baltimore, MD 21287, USA. jpayne5@jhmi.edu
Potash
James B
JB
DePaulo
J Raymond
JR
D001714:Bipolar Disorder / Q000235:genetics*; D002874:Chromosome Mapping; D004252:DNA Mutational Analysis; D004200:Diseases in Twins / Q000235:genetics; D005819:Genetic Markers / Q000235:genetics; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D010641:Phenotype; D012306:Risk
D005819:Genetic Markers