title: Improvements in elastographic contrast-to-noise ratio using spatial-angular compounding.
abstract: Spatial-angular compounding is a new technique developed for improving the signal-to-noise ratio (SNR) in elastography. Under this method, elastograms of a region-of-interest (ROI) are obtained from a spatially weighted average of local strain estimated along different insonification angles. In this article, we investigate the improvements in the strain contrast and contrast-to-noise ratio (CNR) of the spatially compounded elastograms. Spatial angular compounding is also applied and evaluated in conjunction with global temporal stretching. Quantitative experimental results obtained using a single-inclusion tissue-mimicking phantom demonstrate that the strain contrast reduces slightly but the CNR improves by around 8 to 13 dB. We also present experimental spatial angular compounding results obtained from an in vitro thermal lesion in canine liver tissue embedded in a gelatin phantom that demonstrate the improved visual characteristics (due to the improved CNR) of the compound elastogram. The experimental results provide guidelines for the practical range of maximum insonification angles and estimates of the optimum angular increment.
authors.affiliation: Department of Medical Physics, The University of Wisconsin-Madison, Madison, WI 53706, USA.
authors.forename: Udomchai
authors.initials: U
authors.lastname: Techavipoo
authors.forename: Tomy
authors.initials: T
authors.lastname: Varghese
mesh_terms: D000818:Animals; D004285:Dogs; D004548:Elasticity; D005782:Gels; D007090:Image Interpretation, Computer-Assisted; D008099:Liver / Q000000981:diagnostic imaging*; D019047:Phantoms, Imaging; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D014463:Ultrasonography
chemical_list: D005782:Gels