title: Magnetic resonance imaging and diffusion-weighted imaging in methylmalonic acidemia.
abstract: Methylmalonic acidemia (MMA) is an inborn disorder of amino acid metabolism, often presenting with neurological symptoms. We present the results of magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) of the brain in a 16-month-old male patient with classic neurological and laboratory findings for MMA. MRI demonstrated the hyperintensity within globi pallidi both on T2-weighted image and DWI during the acute episode of metabolic acidosis.
authors.affiliation: Department of Radiology, Suleyman Demirel University School of Medicine, Isparta, Turkey. ahmetysd@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Yeşildağ
authors.forename: A
authors.initials: A
authors.lastname: Ayata
authors.forename: B
authors.initials: B
authors.lastname: Baykal
authors.forename: M
authors.initials: M
authors.lastname: Koroglu
authors.forename: H
authors.initials: H
authors.lastname: Yildiz
authors.forename: B
authors.initials: B
authors.lastname: Oral
authors.forename: F
authors.initials: F
authors.lastname: Oktem
authors.forename: O
authors.initials: O
authors.lastname: Oyar
mesh_terms: D000138:Acidosis / Q000473:pathology*; D000592:Amino Acid Metabolism, Inborn Errors / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D005917:Globus Pallidus / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D008764:Methylmalonic Acid / Q000097:blood*
chemical_list: D008764:Methylmalonic Acid