Genetic variation analyses by Pyrosequencing.
Pyrosequencing is a real-time bioluminometric technique for determination of nucleic acid sequence. Here, we review recent advances and discuss new applications of this technique. Cost reduction efforts and future potentials of this technique for large-scale genotyping applications will also be discussed.
Langaee
Taimour
T
Department of Pharmacy Practice, University of Florida, Center for Pharmacogenomics, Gainesville, FL, USA. langaee@cop.ufl.edu
Ronaghi
Mostafa
M
D003365:Costs and Cost Analysis; D004252:DNA Mutational Analysis; D014644:Genetic Variation; D006239:Haplotypes; D020641:Polymorphism, Single Nucleotide; D017422:Sequence Analysis, DNA / Q000191:economics / Q000379:methods*