Infection by Rhodotorula sp. in children receiving treatment for malignant diseases.
Rhodotorula sp. are commensal yeasts that may cause opportunistic infections. There have been only a few case reports of Rhodotorula fungemia in children with cancer, and in all of them the patients had a central venous catheter inserted. The authors report three nonfatal cases of fungemia by Rhodotorula in patients with post-chemotherapy neutropenia. Two of three patients required catheter removal, and a response was achieved with systemic antifungal therapy. Aggressive therapy may be required for selected high-risk patients.
Pasqualotto
Gilberto Comarú
GC
Pediatric Oncology Unit, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. gcp25400@terra.com.br
Copetti
Felipe Antônio
FA
Meneses
Clarice Franco
CF
Machado
Adão Rogério Leal
AR
Brunetto
Algemir Lunardi
AL
D000293:Adolescent; D000935:Antifungal Agents / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002405:Catheterization, Central Venous / Q000009:adverse effects; D002408:Catheters, Indwelling / Q000382:microbiology; D002648:Child; D005260:Female; D016469:Fungemia / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D016399:Lymphoma, T-Cell / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D012248:Rhodotorula / Q000302:isolation & purification*; D012512:Sarcoma, Ewing / Q000150:complications / Q000188:drug therapy / Q000382:microbiology
D000935:Antifungal Agents; D000970:Antineoplastic Agents