title: Gadolinium encephalopathy in a patient with renal failure.
abstract: Gadolinium chelates are extensively used in MRI studies. Neurotoxicity due to gadolinium chelates is minimal and uncommon. A 57-year-old woman in renal failure developed a subacute encephalopathy after inadvertent repetitive gadolinium contrast administration. An unusual MRI appearance with CSF hyperintensity due to gadolinium diffusion into the CSF is also shown.
authors.affiliation: Division of Critical Care Neurology, Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
authors.forename: Boby Varkey
authors.initials: BV
authors.lastname: Maramattom
authors.forename: Edward M
authors.initials: EM
authors.lastname: Manno
authors.forename: Eelco F M
authors.initials: EF
authors.lastname: Wijdicks
authors.forename: Edward P
authors.initials: EP
authors.lastname: Lindell
mesh_terms: D000648:Amnesia, Retrograde / Q000209:etiology; D001921:Brain / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D001928:Brain Diseases, Metabolic / Q000134:cerebrospinal fluid / Q000139:chemically induced* / Q000503:physiopathology; D015984:Causality; D002555:Cerebrospinal Fluid / Q000737:chemistry / Q000187:drug effects; D003244:Consciousness Disorders / Q000134:cerebrospinal fluid / Q000139:chemically induced / Q000503:physiopathology; D005260:Female; D005682:Gadolinium / Q000493:pharmacokinetics / Q000506:poisoning*; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008657:Metabolic Clearance Rate / Q000502:physiology; D008875:Middle Aged; D018579:Patient Selection; D020127:Recovery of Function; D051437:Renal Insufficiency / Q000150:complications* / Q000378:metabolism / Q000503:physiopathology
chemical_list: D005682:Gadolinium