title: Hypercalcemia in hepatic tuberculosis: a case report in Korea.
abstract: Although primary hyperparathyroidism and malignant diseases account for approximately 90% of the causes of hypercalcemia, they could occur in association with granulomatous diseases such as tuberculosis or sarcoidosis, especially in developing countries. Hepatic tuberculosis is difficult to diagnosis without suspicion in cases with normal findings on chest radiographs. We report a 70-year-old woman who presented with hypercalcemia due to hepatic tuberculosis. The diagnosis was made by a computed tomography scan and laparoscopic evaluation. After treatment with anti-tuberculosis medication, her hypercalcemia resolved. Increased vitamin D synthesis by activated macrophages in the granuloma tissue is the major mechanism of hypercalcemia in tuberculosis.
authors.affiliation: Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Eun Seok
authors.initials: ES
authors.lastname: Kang
authors.forename: Mi Young
authors.initials: MY
authors.lastname: Do
authors.forename: So Young
authors.initials: SY
authors.lastname: Park
authors.forename: Kyu Yeon
authors.initials: KY
authors.lastname: Hur
authors.forename: Chul Woo
authors.initials: CW
authors.lastname: Ahn
authors.forename: Bong Soo
authors.initials: BS
authors.lastname: Cha
authors.forename: Sung Kil
authors.initials: SK
authors.lastname: Lim
authors.forename: Kyung Rae
authors.initials: KR
authors.lastname: Kim
authors.forename: Hyun Chul
authors.initials: HC
authors.lastname: Lee
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000150:complications*; D007723:Korea; D014057:Tomography, X-Ray Computed; D014386:Tuberculosis, Hepatic / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy