Introduction of the HPLC method for the determination of quinolone residues in various muscle tissues.
For use in veterinary sanitary control of foodstuffs and raw materials of animal origin in Slovenia, we developed a routine and confirmation analytical method for determining the residues of enrofloxacin, ciprofloxacin and flumequine in the muscle tissue of cattle, pigs and poultry. For the muscle tissue of freshwater fish, the determination of the flumequine residues was introduced. The results obtained through simultaneous determination of the residues of enrofloxacin, ciprofloxacin and flumequine showed that the values for the examined antibiotics were up to 600 times lower than the prescribed maximum residue levels (MRL). Another advantage of this method is that it covers a wide range of different fluoroquinolones.
Kirbis
Andrej
A
Institute for Food Hygiene and Bromatology, Veterinary Faculty, University of Ljubljana, Gerbiceva 60, SI-1000 Ljubljana, Slovenia. andrej.kirbis@vf.uni-lj.si
Marinsek
Janez
J
Flajs
Vesna Cerkvenik
VC
D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods* / Q000662:veterinary*; D002939:Ciprofloxacin / Q000032:analysis; D000077422:Enrofloxacin; D005399:Fishes; D024841:Fluoroquinolones / Q000032:analysis*; D005506:Food Contamination / Q000032:analysis; D009132:Muscles / Q000737:chemistry*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013552:Swine
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D000077422:Enrofloxacin; D002939:Ciprofloxacin; C012976:flumequine