title: Mineralization mechanism of calcium phosphates under three kinds of Langmuir monolayers.
abstract: Three kinds of Langmuir monolayers formed by dipalmitoylphosphatidylcholine (DPPC), arachidic acid (AA), and octadecylamine (ODA) were used as templates to study the initial stage of nucleation and crystallization of calcium phosphates. It was demonstrated that the combination of calcium ions (or phosphates) to the monolayer/subphase interface is a prerequisite for subsequent nucleation. It was found that calcium phosphate dihydrate (DPCD) formed at 25.0 degrees C for 12 h has a biphasic structure containing both amorphous and crystalline phases. These results showed that calcium phosphates were formed through a multistage assembly process, during which an initial amorphous phase DPCD was followed by a phase transformation into a crystalline phase and then the most stable hydroxyapatite (HAp). This provided new insights into the template-biomineral interaction and a mechanism for biomineralization.
authors.affiliation: Key Laboratory of Colloid and Interface Chemistry (Shandong University), Ministry of Education, Jinan 250100, People's Republic of China.
authors.forename: Li-Juan
authors.initials: LJ
authors.lastname: Zhang
authors.forename: Hong-Guo
authors.initials: HG
authors.lastname: Liu
authors.forename: Xu-Sheng
authors.initials: XS
authors.lastname: Feng
authors.forename: Ren-Jie
authors.initials: RJ
authors.lastname: Zhang
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Ying-Di
authors.initials: YD
authors.lastname: Mu
authors.forename: Jing-Cheng
authors.initials: JC
authors.lastname: Hao
authors.forename: Dong-Jin
authors.initials: DJ
authors.lastname: Qian
authors.forename: Yu-Feng
authors.initials: YF
authors.lastname: Lou