Gadolinium encephalopathy in a patient with renal failure.
Gadolinium chelates are extensively used in MRI studies. Neurotoxicity due to gadolinium chelates is minimal and uncommon. A 57-year-old woman in renal failure developed a subacute encephalopathy after inadvertent repetitive gadolinium contrast administration. An unusual MRI appearance with CSF hyperintensity due to gadolinium diffusion into the CSF is also shown.
Maramattom
Boby Varkey
BV
Division of Critical Care Neurology, Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Manno
Edward M
EM
Wijdicks
Eelco F M
EF
Lindell
Edward P
EP
D000648:Amnesia, Retrograde / Q000209:etiology; D001921:Brain / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D001928:Brain Diseases, Metabolic / Q000134:cerebrospinal fluid / Q000139:chemically induced* / Q000503:physiopathology; D015984:Causality; D002555:Cerebrospinal Fluid / Q000737:chemistry / Q000187:drug effects; D003244:Consciousness Disorders / Q000134:cerebrospinal fluid / Q000139:chemically induced / Q000503:physiopathology; D005260:Female; D005682:Gadolinium / Q000493:pharmacokinetics / Q000506:poisoning*; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008657:Metabolic Clearance Rate / Q000502:physiology; D008875:Middle Aged; D018579:Patient Selection; D020127:Recovery of Function; D051437:Renal Insufficiency / Q000150:complications* / Q000378:metabolism / Q000503:physiopathology
D005682:Gadolinium