Botox therapy for refractory chronic migraine.
Chronic migraine is unfortunately both common and often resistant to treatment even with prophylactic medications known to be effective in populations with episodic migraine. We undertook an open-label study to evaluate the safety and utility of botulinum toxin type A injection therapy for patients with chronic migraine who previously had failed to respond to at least three prophylactic medications.
Conway
Stafford
S
University of South Alabama Headache Center, Mobile, AL 36693, USA.
Delplanche
Curtis
C
Crowder
Jessica
J
Rothrock
John
J
D000328:Adult; D000368:Aged; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy* / Q000517:prevention & control; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D017211:Treatment Failure
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A