title: Effect of self-hypnosis on hay fever symptoms - a randomised controlled intervention study.
abstract: BACKGROUND
  Many people suffer from hay fever symptoms. Hypnosis has proved to be a useful adjunct in the treatment of conditions where allergic phenomena have an important role.
  
  
  METHODS
  Randomised parallel group study over an observation period of two consecutive pollen seasons. Outcome data include nasal flow under hypnosis, pollinosis symptoms from diaries and retrospective assessments, restrictions in well-being and use of anti-allergic medication. We investigated 79 patients with a mean age of 34 years (range 19-54 years; 41 males), with moderate to severe allergic rhinitis to grass or birch pollen of at least 2 years duration and mild allergic asthma. The intervention consisted of teaching self-hypnosis during a mean of 2.4 sessions (SD 1.7; range 2-5 sessions) and continuation of standard anti-allergic pharmacological treatment.
  
  
  RESULTS
  Of 79 randomised patients, 66 completed one, and 52 completed two seasons. Retrospective VAS scores yielded significant improvements in year 1 in patients who had learned self-hypnosis: pollinosis symptoms -29.2 (VAS score, range 0-100; SD 25.4; p < 0.001), restriction of well-being -26.2 (VAS score, range 0-100; SD 28.7; p < 0.001. In year 2, the control group improved significantly having learned self-hypnosis as well: pollinosis symptoms -24.8 (SD 29.1; p < 0.001), restriction of well-being -23.7 (SD 30.0; p < 0.001). Daily self-reports of subjects who learnt self-hypnosis do not show a significant improvement. The hazard ratio of reaching a critical flow of 70% in nasal provocation tests was 0.333 (95% CI 0.157-0.741) after having learnt and applied self-hypnosis.
authors.affiliation: Division of Psychosomatic Medicine, Department of Internal Medicine, University Hospital Basel, Basel, Switzerland. wlangewitz@uhbs.ch
authors.forename: Wolf
authors.initials: W
authors.lastname: Langewitz
authors.forename: Jan
authors.initials: J
authors.lastname: Izakovic
authors.forename: Jane
authors.initials: J
authors.lastname: Wyler
authors.forename: Christian
authors.initials: C
authors.lastname: Schindler
authors.forename: Alexander
authors.initials: A
authors.lastname: Kiss
authors.forename: Andreas J
authors.initials: AJ
authors.lastname: Bircher
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D006990:Hypnosis; D008297:Male; D008875:Middle Aged; D006255:Rhinitis, Allergic, Seasonal / Q000628:therapy*; D012648:Self Care