title: Erythroderma with lichenoid granulomatous features induced by erythropoietin.
abstract: The increasing use of new drugs in cancer therapy, especially growth factors, hormones, and chemotherapies resulted in several reports of unusual skin eruptions. We studied a patient with erythroderma who had received erythropoietin because of myeloma with tumor anemia. The histological features were characterized by a lichenoid, focally granulomatous infiltrate with predominance of histiocytes. It is important for dermatopathologists to recognize this interesting pattern induced by erythropoietin.
authors.affiliation: Department of Dermatology, University of Graz, Graz, Austria. ingrid.wolf@meduni-graz.at
authors.forename: Ingrid H
authors.initials: IH
authors.lastname: Wolf
authors.forename: J
authors.initials: J
authors.lastname: Smolle
authors.forename: L
authors.initials: L
authors.lastname: Cerroni
authors.forename: H
authors.initials: H
authors.lastname: Kerl
mesh_terms: D000740:Anemia / Q000188:drug therapy / Q000209:etiology; D015703:Antigens, CD / Q000378:metabolism; D003873:Dermatitis, Exfoliative / Q000139:chemically induced* / Q000378:metabolism / Q000473:pathology*; D004921:Erythropoietin / Q000009:adverse effects* / Q000627:therapeutic use; D006099:Granuloma / Q000473:pathology*; D006644:Histiocytes / Q000378:metabolism / Q000473:pathology; D006801:Humans; D017512:Lichenoid Eruptions / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications; D013601:T-Lymphocytes / Q000378:metabolism / Q000473:pathology
chemical_list: D015703:Antigens, CD; D004921:Erythropoietin