pFind: a novel database-searching software system for automated peptide and protein identification via tandem mass spectrometry.
Research in proteomics requires powerful database-searching software to automatically identify protein sequences in a complex protein mixture via tandem mass spectrometry. In this paper, we describe a novel database-searching software system called pFind (peptide/protein Finder), which employs an effective peptide-scoring algorithm that we reported earlier. The pFind server is implemented with the C++ STL, .Net and XML technologies. As a result, high speed and good usability of the software are achieved.
Li
Dequan
D
Institute of Computing Technology, Chinese Academy of Sciences Beijing 100080, China. dqli@jdl.ac.cn
Fu
Yan
Y
Sun
Ruixiang
R
Ling
Charles X
CX
Wei
Yonggang
Y
Zhou
Hu
H
Zeng
Rong
R
Yang
Qiang
Q
He
Simin
S
Gao
Wen
W
D000465:Algorithms; D001185:Artificial Intelligence; D003628:Database Management Systems; D030562:Databases, Protein; D020869:Gene Expression Profiling / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods*; D011506:Proteins / Q000032:analysis / Q000737:chemistry* / Q000145:classification; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software; D014584:User-Computer Interface
D011506:Proteins