Dizygotic twin pregnancy conceived with assisted reproductive technology associated with chromosomal anomaly, imprinting disorder, and monochorionic placentation.
Assisted reproductive technology (ART) has now become a cornerstone of treatment for involuntary infertility. Recent studies have raised concern regarding potential associations between ART and chromosomal aneuploidy, imprinting anomalies, and monochorionic placentation in dizygotic (DZ) twins. We report a case of DZ twins conceived by ART in which all three problems coexist.
Yoon
Grace
G
Department of Pediatrics, Division of Medical Genetics, University of California-San Francisco, San Francisco, CA, USA.
Beischel
Linda S
LS
Johnson
John P
JP
Jones
Marilyn C
MC
D001506:Beckwith-Wiedemann Syndrome / Q000209:etiology* / Q000235:genetics; D002823:Chorion; D002869:Chromosome Aberrations; D004200:Diseases in Twins / Q000209:etiology* / Q000235:genetics; D018392:Genomic Imprinting; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010920:Placenta; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects*; D014429:Twins, Dizygotic