New antibiotic produced by bacteria, 5-beta-D-xylofuranosylneamine.
A new aminoglycoside antibiotic was isolated from the fermentation broths of two strains of Bacillus species. The antibiotic is active against gram-positive and some gram-negative bacteria, and its antimicrobial spectrum is similar to that of ribostamycin. The chemical structure was determined to be 5-beta-d-xylofuranosylneamine, which is identical to the deacylated product obtained from butirosin A.
Horii
S
S
Nogami
I
I
Mizokami
N
N
Arai
Y
Y
Yoneda
M
M
D000215:Acylation; D000617:Aminoglycosides / Q000737:chemistry / Q000378:metabolism*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000378:metabolism*; D001407:Bacillus / Q000254:growth & development / Q000378:metabolism*; D002076:Butirosin Sulfate / Q000737:chemistry / Q000378:metabolism*; D005285:Fermentation; D005601:Framycetin; D006868:Hydrolysis
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D005601:Framycetin; D002076:Butirosin Sulfate; C488396:neamine