title: Does lesion size determine the success rate of photodynamic therapy for age-related macular degeneration?
abstract: Photodynamic therapy (PDT) is a new evidence-based treatment modality available for choroidal neovascularisation (CNV) secondary to age-related macular degeneration (AMD). Eligibility for PDT is based on the morphological classification of the neovascular complex, the benefit being greater in classic with no occult lesions. Lesion size is also shown to be a predictive factor for treatment benefit. This retrospective case series looked at effect of initial and final lesion size on the visual outcome of patients with subfoveal classic with no occult CNV and found that increasing initial and final lesion size is associated with poorer visual outcome.
authors.affiliation: West Kent Eye Centre, Princess Royal University Hospital, Orpington, Kent BR6 8ND, UK. Senswathi@aol.com
authors.forename: S
authors.initials: S
authors.lastname: Sivaprasad
authors.forename: G M
authors.initials: GM
authors.lastname: Saleh
authors.forename: H
authors.initials: H
authors.lastname: Jackson
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008268:Macular Degeneration / Q000188:drug therapy* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D012160:Retina / Q000473:pathology*; D012189:Retrospective Studies; D012815:Signal Processing, Computer-Assisted; D016896:Treatment Outcome; D014792:Visual Acuity
chemical_list: D017319:Photosensitizing Agents