title: Investigating the relationship between hemodynamic and metabolic parameters in portal triade occlusion following hemorrhagic shock.
abstract: OBJECTIVE
  To determine whether metabolic and hemodynamic parameters are "mathematically" coupled in rats submitted to portal triad occlusion following controlled hemorrhagic shock state.
  
  
  METHODS
  Pearson's coefficient (r-value) analysis was performed. Differences considered significant at p < 0.05 and -0.50 > r > 0.50.
  
  
  RESULTS
  It was observed that there is a direct proportional relationship to HCO3- with pCO2 (r = 0.66), base deficit (r = 0.87) and inverse with serum lactate (r = -0.54). pCO2 was directly associated with MAP (r = 0.51), and inversely with pH (r = -0.64). Hematocrit was directly associated with HR (r = 0.72) and CI (r = 0.76), and serum lactated was inversely associated with base deficit (r = -0.61).
  
  
  CONCLUSIONS
  In rats submitted to Pringle's maneuver during 15 minutes following hemorrhagic shock state, there is a mathematical coupling with a very good correlation between several hemodynamic and metabolic variables.
authors.affiliation: Trauma Surgery Division, Department of Surgery, Faculty of Medical Sciences, Unicamp, Campinas, Brazil. mikefox@uol.com.br
authors.forename: Mauro José
authors.initials: MJ
authors.lastname: Fontelles
authors.forename: Mario
authors.initials: M
authors.lastname: Mantovani
authors.forename: Elcio Shiyoiti
authors.initials: ES
authors.lastname: Hirano
authors.forename: Rosana Celestina
authors.initials: RC
authors.lastname: Morandin
mesh_terms: D000818:Animals; D006439:Hemodynamics; D008297:Male; D011169:Portal Vein; D051381:Rats; D017208:Rats, Wistar; D012771:Shock, Hemorrhagic / Q000378:metabolism* / Q000503:physiopathology*