title: [A study on europium sensitized chemiluminescence of pipemidic acid].
abstract: A flow injection chemiluminescence method for the determination of Pipemidic acid (PPA) was developed. It is based on luminescence produced with KMnO4-Na2S2O4 CL system sensitized by Eu3+-PPA. The familar excipients such as starch and dextrine do not cause interference. The several kinds of affect on chemiluminescence were studied. The linear range and detection limit for PPA are 7.00 x 10(-9)-9.00 x 10(-7) mol x L(-1) and 4.09 x 10(-9) mol x L(-1), respectively. This method have successfully been applied to the determination of PPA in tablet and urine. And the mechanism of chemiluminescence is proposed.
authors.affiliation: Department of Chemistry, Capital Normal University, Beijing 100037, China.
authors.forename: Xia
authors.initials: X
authors.lastname: Li
authors.forename: Hong
authors.initials: H
authors.lastname: Qiang
authors.forename: Xiao-li
authors.initials: XL
authors.lastname: Wang
authors.forename: Shi-lü
authors.initials: SL
authors.lastname: Chen
authors.forename: Hui-chun
authors.initials: HC
authors.lastname: Zhao
mesh_terms: D002563:Cerium / Q000494:pharmacology; D004347:Drug Interactions; D005063:Europium / Q000494:pharmacology*; D049449:Luminescence; D008163:Luminescent Measurements / Q000295:instrumentation* / Q000379:methods*; D010876:Pipemidic Acid / Q000737:chemistry*
chemical_list: D002563:Cerium; D005063:Europium; D010876:Pipemidic Acid