title: An epidemic of occupational contact dermatitis from an acrylic glue.
abstract: Dermatological examinations were performed in 81 workers involved in the manufacture of electric coils for television displays, who had worked for 4 years in contact with a glue containing isobornyl acrylate, acrylic acid, N,N dimethyleneacrylamide, phosphine oxide, bis(2,6-dimethoxybenzoyl) (2,4,4-trimethylpentyl)- and beta-carboxyethyl acrylate. The glue was cured by 350-500-nm ultraviolet and visible radiations. Acrylate-specific dermal lesions were detected in 21 (25.9%) people. Occupational irritant contact dermatitis was diagnosed in 12 (15%) of the workers and occupational allergic contact dermatitis in 9 (11.2%). 12 people reacted to acrylates. Cross-reactions with methacrylates were not observed. The highest number of positive tests was obtained with triethyleneglycol diacrylate (10 people) and diethyleneglycol diacrylate (9), followed by 1,6-hexanediol diacrylate (5), 1,4-butanediol diacrylate (4), beta-carboxyethyl acrylate (3), tripropyleneglycol diacrylate (2) and pentaerythritol triacrylate (2). No cases of allergy to isobornyl acrylate, N,N-methylenebisacrylamide or phosphine oxide were noted.
authors.affiliation: Department of Occupational Diseases, Nofer Institute of Occupational Medicine, 8 Sw. Teresy Street, 90-950 Lodz, Poland. marswier@imp.lodz.pl
authors.forename: Marta
authors.initials: M
authors.lastname: Kiec-Swierczynska
authors.forename: Beata
authors.initials: B
authors.lastname: Krecisz
authors.forename: Dominika
authors.initials: D
authors.lastname: Swierczynska-Machura
authors.forename: Joanna
authors.initials: J
authors.lastname: Zaremba
mesh_terms: D000179:Acrylates / Q000009:adverse effects*; D000269:Adhesives / Q000009:adverse effects*; D000328:Adult; D000485:Allergens / Q000009:adverse effects; D002617:Chemical Industry; D017449:Dermatitis, Allergic Contact / Q000453:epidemiology* / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000453:epidemiology* / Q000209:etiology*; D005260:Female; D006229:Hand Dermatoses / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D011044:Poland / Q000453:epidemiology
chemical_list: D000179:Acrylates; D000269:Adhesives; D000485:Allergens