Severe transient neutropenia associated with acute human immunodeficiency virus type 1 infection.
Severe neutropenia associated with primary HIV infection is unusual. We report the fifth case in a 50-year-old male with a neutrophil count of 500/mm(3) and a platelet count of 92,000/mm(3) at the time of early HIV-1 seroconversion. In all previously published cases and in our case, severe neutropenia was a very early sign of acute HIV infection, and it regressed spontaneously and quickly. HIV testing should be recommended when severe neutropenia is observed, especially in the context of a flu-like or mononucleosis-like infectious syndrome.
Colson
Philippe
P
Laboratoire de Bactériologie-Virologie, Centre Hospitalo-Universitaire Timone et CNRS UMR 6020 IFR48 Université de la Méditerranée, 264 rue Saint-Pierre 13385 Marseille Cedex 05, France.
Foucault
Cédric
C
Mokhtari
Malika
M
Tamalet
Catherine
C