title: Infection by Rhodotorula sp. in children receiving treatment for malignant diseases.
abstract: Rhodotorula sp. are commensal yeasts that may cause opportunistic infections. There have been only a few case reports of Rhodotorula fungemia in children with cancer, and in all of them the patients had a central venous catheter inserted. The authors report three nonfatal cases of fungemia by Rhodotorula in patients with post-chemotherapy neutropenia. Two of three patients required catheter removal, and a response was achieved with systemic antifungal therapy. Aggressive therapy may be required for selected high-risk patients.
authors.affiliation: Pediatric Oncology Unit, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. gcp25400@terra.com.br
authors.forename: Gilberto Comarú
authors.initials: GC
authors.lastname: Pasqualotto
authors.forename: Felipe Antônio
authors.initials: FA
authors.lastname: Copetti
authors.forename: Clarice Franco
authors.initials: CF
authors.lastname: Meneses
authors.forename: Adão Rogério Leal
authors.initials: AR
authors.lastname: Machado
authors.forename: Algemir Lunardi
authors.initials: AL
authors.lastname: Brunetto
mesh_terms: D000293:Adolescent; D000935:Antifungal Agents / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002405:Catheterization, Central Venous / Q000009:adverse effects; D002408:Catheters, Indwelling / Q000382:microbiology; D002648:Child; D005260:Female; D016469:Fungemia / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D016399:Lymphoma, T-Cell / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D012248:Rhodotorula / Q000302:isolation & purification*; D012512:Sarcoma, Ewing / Q000150:complications / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000935:Antifungal Agents; D000970:Antineoplastic Agents