title: A comparison of haemodynamic response with pethidine vs. butorphanol in open cholecystectomy cases.
abstract: OBJECTIVE
  The present study was undertaken to compare the haemodynamic responses with pethidine vs. Butorphanol intraoperatively in open cholecystectomy cases in KMCTH.
  
  
  METHODS
  In this randomized study, all together 40 patients undergoing routine cholecystectomy surgery were included. Group A received Pethidine 1 mg/kg and Group B received Butorphanol 0.04 mg/kg intraoperatively. Heart rate and blood pressure were recorded before injection of the drug, after injection, before intubation, after intubation, before skin incision, after incision, before extubation and after extubation data analysis was done using independent sample t test.
  
  
  RESULTS
  Our study showed no statistical significance in haemodynamic responses with either pethidine or Butorphanol in open cholecystectomy cases.
  
  
  CONCLUSIONS
  Both drugs appear equally good analgesics in our study.
authors.affiliation: Department of Anaesthesiology, Kathmandu Medical College, Sinamangal, KTM.
authors.forename: S
authors.initials: S
authors.lastname: Tabedar
authors.forename: S K
authors.initials: SK
authors.lastname: Maharjan
authors.forename: B R
authors.initials: BR
authors.lastname: Shrestha
authors.forename: S
authors.initials: S
authors.lastname: Shrestha
mesh_terms: D000759:Adjuvants, Anesthesia / Q000494:pharmacology*; D000328:Adult; D000701:Analgesics, Opioid / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D002077:Butorphanol / Q000494:pharmacology*; D002763:Cholecystectomy; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008614:Meperidine / Q000494:pharmacology*; D008875:Middle Aged
chemical_list: D000759:Adjuvants, Anesthesia; D000701:Analgesics, Opioid; D008614:Meperidine; D002077:Butorphanol