title: Imaging addiction with PET: is insight in sight?
abstract: Neurochemical imaging studies can identify molecular targets of abused drugs and link them to the underlying pathology associated with behaviors such as drug dependence, addiction and withdrawal. positron emission tomography (PET) is opening new avenues for the investigation of the neurochemical disturbances underlying drug abuse and addiction and the in vivo mechanisms by which medications might ameliorate these conditions. PET can identify vulnerable human populations, treatment strategies and monitor treatment efficacy. Thus, with this tool and the knowledge it provides, the potential for developing novel drugs and treatment strategies for drug addiction is now close at hand.
authors.affiliation: Department of Neurobiology & Behavior, Stony Brook University, Stony Brook, NY 11794, USA. wynne@bnl.gov
authors.forename: Wynne K
authors.initials: WK
authors.lastname: Schiffer
authors.forename: Dianne E
authors.initials: DE
authors.lastname: Lee
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Brodie
authors.forename: Stephen L
authors.initials: SL
authors.lastname: Dewey
mesh_terms: D000818:Animals; D005544:Forecasting; D006801:Humans; D049268:Positron-Emission Tomography / Q000295:instrumentation / Q000706:statistics & numerical data* / Q000639:trends; D019966:Substance-Related Disorders / Q000175:diagnosis*; D009626:Terminology as Topic