Primary structure, recombinant expression and homology modelling of human brain prolyl oligopeptidase, an important therapeutic target in the treatment of neuropsychiatric diseases.
Tarragó
Teresa
T
Institut de Recerca Biomèdica de Barcelona, Parc Científic de Barcelona, E-08028 Barcelona, Spain.
Sabidó
Eduard
E
Kogan
Marcelo Javier
MJ
de Oliveira
Eliandre
E
Giralt
Ernest
E
D000595:Amino Acid Sequence; D000818:Animals; D001921:Brain / Q000201:enzymology*; D002493:Central Nervous System Diseases / Q000188:drug therapy / Q000201:enzymology; D015870:Gene Expression; D049673:History, 20th Century; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy / Q000201:enzymology; D008958:Models, Molecular; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry / Q000266:history; D055232:Proline-Rich Protein Domains; D000085822:Prolyl Oligopeptidases; D011487:Protein Conformation; D040901:Proteomics; D011994:Recombinant Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D012697:Serine Endopeptidases / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D013552:Swine
D010455:Peptides; D011994:Recombinant Proteins; D012697:Serine Endopeptidases; C000705287:PREPL protein, human; D000085822:Prolyl Oligopeptidases