Change in atherosclerosis progression in HIV-infected patients: ANRS Aquitaine Cohort, 1999-2004.
This study reported the changes in carotid intima-media thickness (IMT) during a 36-month period in 233 HIV-infected patients. Median IMT increased in the first 12 months and then decreased by month 36. The prevalence of treatment with lipid-lowering agents and protease inhibitor-free highly active antiretroviral therapy regimens increased, whereas smoking prevalence decreased. The progression of atherosclerosis in HIV-infected patients can be controlled. The impact of individual measures to reduce the cardiovascular risk should be evaluated further.
Thiébaut
Rodolphe
R
INSERM EMI 0338, ISPED, Université Victor Segalen Bordeaux 2, 33076 Bordeaux, France.
Aurillac-Lavignolle
Valérie
V
Bonnet
Fabrice
F
Ibrahim
Nagi
N
Cipriano
Claire
C
Neau
Didier
D
Dupon
Michel
M
Dabis
François
F
Mercié
Patrick
P
D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D001161:Arteriosclerosis / Q000473:pathology / Q000628:therapy / Q000821:virology*; D002340:Carotid Artery Diseases / Q000473:pathology / Q000821:virology; D017536:Carotid Artery, Common; D008076:Cholesterol, HDL / Q000097:blood; D018450:Disease Progression; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D005602:France; D015658:HIV Infections / Q000150:complications* / Q000473:pathology / Q000628:therapy; D015497:HIV-1; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012907:Smoking; D017539:Tunica Intima / Q000473:pathology
D008076:Cholesterol, HDL; D000960:Hypolipidemic Agents