title: [Advances on biological activities of coumarins].
abstract: This paper reviewed the advances on effective constituents and biological activities of coumarins in recent ten years. Coumarins are a group of important natural compounds, and have been found to have multi-biological activities such as anti-HIV, anti-tumor, anti-hypertension, anti-arrhythmia, anti-osteoporosis, assuaging pain, preventing asthma and antisepsis. Therefore, further investigation should emphasize on improving techniques for extraction and separation, searching the effective precursory compound, and synthesizing and screening out courmarin derivatives with high activity and low toxicity.
authors.affiliation: Tianjin Medical University, Tianjin 300070, China. pharmgao@tju.edu.cn
authors.forename: Shao-Yul
authors.initials: SY
authors.lastname: Zhang
authors.forename: Lin
authors.initials: L
authors.lastname: Meng
authors.forename: Wen-Yuan
authors.initials: WY
authors.lastname: Gao
authors.forename: Nai-Ning
authors.initials: NN
authors.lastname: Song
authors.forename: Wei
authors.initials: W
authors.lastname: Jia
authors.forename: Hong-Quan
authors.initials: HQ
authors.lastname: Duan
mesh_terms: D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology; D019380:Anti-HIV Agents / Q000494:pharmacology*; D000959:Antihypertensive Agents / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D003374:Coumarins / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D000889:Anti-Arrhythmia Agents; D019380:Anti-HIV Agents; D000959:Antihypertensive Agents; D000972:Antineoplastic Agents, Phytogenic; D003374:Coumarins