A comparison of haemodynamic response with pethidine vs. butorphanol in open cholecystectomy cases.
OBJECTIVE
The present study was undertaken to compare the haemodynamic responses with pethidine vs. Butorphanol intraoperatively in open cholecystectomy cases in KMCTH.


METHODS
In this randomized study, all together 40 patients undergoing routine cholecystectomy surgery were included. Group A received Pethidine 1 mg/kg and Group B received Butorphanol 0.04 mg/kg intraoperatively. Heart rate and blood pressure were recorded before injection of the drug, after injection, before intubation, after intubation, before skin incision, after incision, before extubation and after extubation data analysis was done using independent sample t test.


RESULTS
Our study showed no statistical significance in haemodynamic responses with either pethidine or Butorphanol in open cholecystectomy cases.


CONCLUSIONS
Both drugs appear equally good analgesics in our study.
Tabedar
S
S
Department of Anaesthesiology, Kathmandu Medical College, Sinamangal, KTM.
Maharjan
S K
SK
Shrestha
B R
BR
Shrestha
S
S
D000759:Adjuvants, Anesthesia / Q000494:pharmacology*; D000328:Adult; D000701:Analgesics, Opioid / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D002077:Butorphanol / Q000494:pharmacology*; D002763:Cholecystectomy; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008614:Meperidine / Q000494:pharmacology*; D008875:Middle Aged
D000759:Adjuvants, Anesthesia; D000701:Analgesics, Opioid; D008614:Meperidine; D002077:Butorphanol