title: Antifungal activity of some Brazilian Hypericum species.
abstract: Crude methanolic extracts and fractions from the aerial parts of seven species of Hypericum (H. caprifoliatum Cham. and Schltdl., H. carinatum Griseb., H. connatum Lam., H. ternum A. St.-Hil., H. myrianthum Cham. and Schltdl., H. piriai Arechav. and H. polyanthemum Klotzsch ex Reichardt) growing in southern Brazil were analyzed for their in vitro antifungal activity against a panel of standardized and clinical opportunistic pathogenic yeasts and filamentous fungi, including dermatophytes, by the agar dilution method. Chloroform and hexane extracts of H. ternum showed the greatest activity among extracts tested.
authors.affiliation: Programa de Pós Graduação em Ciências Farmacêuticas, UFRGS, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Porto Alegre 90610-000, Brazil.
authors.forename: R
authors.initials: R
authors.lastname: Fenner
authors.forename: M
authors.initials: M
authors.lastname: Sortino
authors.forename: S M Kuze
authors.initials: SM
authors.lastname: Rates
authors.forename: R
authors.initials: R
authors.lastname: Dall'Agnol
authors.forename: A
authors.initials: A
authors.lastname: Ferraz
authors.forename: A P
authors.initials: AP
authors.lastname: Bernardi
authors.forename: D
authors.initials: D
authors.lastname: Albring
authors.forename: C
authors.initials: C
authors.lastname: Nör
authors.forename: G
authors.initials: G
authors.lastname: von Poser
authors.forename: E
authors.initials: E
authors.lastname: Schapoval
authors.forename: S
authors.initials: S
authors.lastname: Zacchino
mesh_terms: D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D002175:Candida / Q000187:drug effects*; D006801:Humans; D020902:Hypericum; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D010936:Plant Extracts