title: Microbiological assays and bioautography of maytansine and its homologues.
abstract: A quantitative microbiological assay and a bioautography system with Penicillium avellaneum UC-4376 was developed for the antitumor drugs maytansine, and its homologues, maytanprine and maytanbutine. The susceptibility of the assay is 1.5 mug/ml.
authors.forename: L J
authors.initials: LJ
authors.lastname: Hanka
authors.forename: M S
authors.initials: MS
authors.lastname: Barnett
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis*; D002845:Chromatography; D004305:Dose-Response Relationship, Drug; D008453:Maytansine / Q000032:analysis* / Q000494:pharmacology; D010407:Penicillium / Q000187:drug effects
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D008453:Maytansine