Autopsy case of primary choriocarcinoma of the urinary bladder.
Choriocarcinomas usually develop in the uterus and ovaries in the female, being extremely rare in the extragenital organs in the male. Extragenital choriocarcinomas in the male usually develop in the mediastinum or retroperitoneum. The frequency of choriocarcinoma in the urinary bladder is extremely low. The purpose of the present paper was to report an autopsy case of choriocarcinoma in the urinary bladder in the male. An 81-year-old male patient with macrohematuria was first diagnosed with transitional cell carcinoma (TCC). At autopsy a hemorrhagic necrotic tumor, which was found in the urinary bladder with metastatic lesions in the lungs, was diagnosed as choriocarcinoma microscopically. There was no evidence for choriocarcinoma derived from any other organs than the urinary bladder, although there were metastatic lesions in both lungs and the direct invasion into the prostate. From these findings it is concluded that the tumor was a primary choriocarcinoma in the urinary bladder in a male patient. Choriocarcinoma of the urinary bladder is very rare, but the prognosis is extremely poor in comparison with TCC even in the urinary bladder. Therefore, it is essential to clearly discriminate between choriocarcinomas and TCC.
Minamino
Keizo
K
First Department of Pathology, Kansai Medical University, Moriguchi, Osaka, Japan.
Adachi
Yasushi
Y
Okamura
Akiharu
A
Kushida
Taketoshi
T
Sugi
Motohiko
M
Watanabe
Masato
M
Muguruma
Kouei
K
Sugao
Hideki
H
Suzuki
Yasuhiro
Y
Iwasaki
Masayoshi
M
Nakano
Keiji
K
Koike
Yasushi
Y
Wang
Jianfeng
J
Mukaide
Hiromi
H
Zhang
Yuming
Y
Matsuda
Tadashi
T
Matsumura
Miyo
M
Ikehara
Susumu
S
D000368:Aged; D000369:Aged, 80 and over; D001344:Autopsy; D002295:Carcinoma, Transitional Cell / Q000473:pathology; D002822:Choriocarcinoma / Q000378:metabolism / Q000473:pathology*; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000032:analysis; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D001749:Urinary Bladder Neoplasms / Q000378:metabolism / Q000473:pathology*
D018997:Chorionic Gonadotropin, beta Subunit, Human