title: Solid-phase synthesis of photochromic spiropyrans.
abstract: [reaction: see text] A convenient solid-phase synthesis of spiropyrans is described. A succinate linker was employed, which allows base-catalyzed cleavage of the desired photochromophore derivatized with a succinimide. Excellent yields and purities were obtained for the compounds that comprise a library of 23 spiropyrans. Opening of the succinimide ring in spiropyran could be realized under mild conditions.
authors.affiliation: Laboratorium für Organische Chemie, ETH-Hönggerberg HCI H335, CH-8093 Zürich, Switzerland.
authors.forename: Weili
authors.initials: W
authors.lastname: Zhao
authors.forename: Erick M
authors.initials: EM
authors.lastname: Carreira