title: Is buscopan effective in meat bolus obstruction?
abstract: OBJECTIVE
  To assess the efficacy of hyoscine butyl bromide (buscopan) in relieving oesophageal meat bolus obstruction.
  
  
  METHODS
  Retrospective review of case notes.
  
  
  METHODS
  Secondary otorhinolaryngology care.
  
  
  METHODS
  Twenty-nine patients who presented to the Accidents & Emergency department satisfying, inclusion criteria: (i) >or=16 years old, (ii) patients with only meat bolus obstruction and (iii) had either only buscopan or no medications. Exclusion criteria were: (i) <16 years of age, (ii) patients who received any medications other than or in addition to buscopan, (iii) other foreign body obstructions and (iv) any patient in whom the approximate time of resolution of obstruction was not documented.
  
  
  RESULTS
  Twenty-nine patients with 31 episodes of obstruction were analysed. Twenty-two episodes were treated with buscopan and in 18 (82%) the obstruction was relieved. Two had spontaneous relief >24 h later and two had surgical disimpaction. In nine episodes, where no medications were given, seven (78%) cleared spontaneously and two had surgical removal. Fisher's exact test failed to show any significant difference between the two groups. The study groups were too small and power calculation showed that the number required for statistically validated result would be 140 in each group.
  
  
  CONCLUSIONS
  Routine use of buscopan in oesophageal obstruction especially in the upper two-thirds needs to be reviewed because of the possibility of side-effects and lack of objective evidence of its efficacy.
authors.affiliation: Sunderland Royal Hospital, Sunderland, UK. ligythomas@hotmail.com
authors.forename: L
authors.initials: L
authors.lastname: Thomas
authors.forename: C
authors.initials: C
authors.lastname: Webb
authors.forename: S
authors.initials: S
authors.lastname: Duvvi
authors.forename: T
authors.initials: T
authors.lastname: Jones
authors.forename: K T V
authors.initials: KT
authors.lastname: Reddy
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002086:Butylscopolammonium Bromide / Q000627:therapeutic use*; D015154:Esophageal Motility Disorders / Q000188:drug therapy* / Q000209:etiology*; D005260:Female; D005547:Foreign Bodies / Q000150:complications*; D006801:Humans; D008297:Male; D008461:Meat Products; D008487:Medical History Taking; D008875:Middle Aged; D010276:Parasympatholytics / Q000627:therapeutic use*; D012189:Retrospective Studies
chemical_list: D010276:Parasympatholytics; D002086:Butylscopolammonium Bromide