Antifungal activity of some Brazilian Hypericum species.
Crude methanolic extracts and fractions from the aerial parts of seven species of Hypericum (H. caprifoliatum Cham. and Schltdl., H. carinatum Griseb., H. connatum Lam., H. ternum A. St.-Hil., H. myrianthum Cham. and Schltdl., H. piriai Arechav. and H. polyanthemum Klotzsch ex Reichardt) growing in southern Brazil were analyzed for their in vitro antifungal activity against a panel of standardized and clinical opportunistic pathogenic yeasts and filamentous fungi, including dermatophytes, by the agar dilution method. Chloroform and hexane extracts of H. ternum showed the greatest activity among extracts tested.
Fenner
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R
Programa de Pós Graduação em Ciências Farmacêuticas, UFRGS, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Porto Alegre 90610-000, Brazil.
Sortino
M
M
Rates
S M Kuze
SM
Dall'Agnol
R
R
Ferraz
A
A
Bernardi
A P
AP
Albring
D
D
Nör
C
C
von Poser
G
G
Schapoval
E
E
Zacchino
S
S
D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D002175:Candida / Q000187:drug effects*; D006801:Humans; D020902:Hypericum; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
D000935:Antifungal Agents; D010936:Plant Extracts