title: Anti-diarrhoeal activity of Butea monosperma in experimental animals.
abstract: The anti-diarrhoeal potential of the ethanolic extract of stem bark of Butea monosperma (Lam) Kuntz has been evaluated using several experimental models in Wistar albino rats. The extract inhibited castor oil induced diarrhoea and PGE(2) induced enteropooling in rats; it also reduced gastrointestinal motility after charcoal meal administration. The results obtained establish the efficacy and substantiate the use of this herbal remedy as a non-specific treatment for diarrhoea in folk medicine.
authors.affiliation: Department of Pharmacology, K.P. College of Pharmacy, Thiruvannamalai, India.
authors.forename: A
authors.initials: A
authors.lastname: Gunakkunru
authors.forename: K
authors.initials: K
authors.lastname: Padmanaban
authors.forename: P
authors.initials: P
authors.lastname: Thirumal
authors.forename: J
authors.initials: J
authors.lastname: Pritila
authors.forename: G
authors.initials: G
authors.lastname: Parimala
authors.forename: N
authors.initials: N
authors.lastname: Vengatesan
authors.forename: N
authors.initials: N
authors.lastname: Gnanasekar
authors.forename: James B
authors.initials: JB
authors.lastname: Perianayagam
authors.forename: S K
authors.initials: SK
authors.lastname: Sharma
authors.forename: K K
authors.initials: KK
authors.lastname: Pillai
mesh_terms: D000818:Animals; D000930:Antidiarrheals / Q000494:pharmacology / Q000627:therapeutic use* / Q000633:toxicity; D031290:Butea; D003967:Diarrhea / Q000139:chemically induced / Q000188:drug therapy*; D005769:Gastrointestinal Motility / Q000187:drug effects; D008297:Male; D051379:Mice; D008517:Phytotherapy; D024301:Plant Bark; D028321:Plant Preparations / Q000494:pharmacology / Q000627:therapeutic use* / Q000633:toxicity; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000930:Antidiarrheals; D028321:Plant Preparations