title: [Specialised pediatric pathology service].
abstract: Leningrad Regional Children's Bureau of Pathology was established in May 1992. The program of this bureau consisted of: revealing causes of early and late abortions; assessment of ultrasound diagnosis of congenital deficiencies of fetus development and clinical assessment of chronic placental insufficiency; pathogenetic explanation of intrauterine fetuses death; prognosis of neonatal pathology; systemic analysis of dynamics of perinatal, natal and infant mortality; organisation of independant expertise of medical causes of reproductive losses. The following principles in the work of the bureau were established: 1) mass investigation of placentas of newborns; 2) use of urgent pathomorphological diagnosis which allows to present information about placentas not later than 24 hrs after the delivery; 3) complex investigation of placentas with the use of various methods; 4) systemic informational analysis of placental pathology; 5) constant updating of physicians knowledge in the field of practical placentology. Results of mass placentas investigation show a principal pathogenetic role of ascending infection in perinatal mortality in opportunistic pathogenic microflora with the development of inflammatory responses in the system mother-placenta-fetus.
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Grinenko
authors.forename: N G
authors.initials: NG
authors.lastname: Glukhovets
mesh_terms: D003153:Community Health Services; D005260:Female; D005313:Fetal Death / Q000473:pathology; D006078:Government Programs; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000473:pathology / Q000517:prevention & control; D010338:Pathology, Clinical; D010372:Pediatrics; D010500:Perinatology; D010920:Placenta / Q000473:pathology; D010922:Placenta Diseases / Q000473:pathology / Q000517:prevention & control; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology / Q000517:prevention & control; D012426:Russia; D013997:Time Factors