title: A pharmacy-based coaching program to improve adherence to antidepressant treatment among primary care patients.
abstract: The effects on adherence and depressive symptoms of a community pharmacy-based coaching program, including a take-home videotape, were evaluated in a randomized controlled trial in the Netherlands. A total of 147 depressed primary care patients who had a new antidepressant prescription were included in the study. Adherence was measured with an electronic pill container and was also derived from pharmacy medication records; the latter method was associated with an overestimation of adherence of only 5 percent. Intention-to-treat analyses showed no intervention effect on adherence (73 percent compared with 76 percent), whereas analyses of patients who received the intervention (per protocol) showed improved adherence (73 percent compared with 90 percent). Neither analysis showed effects on depressive symptoms.
authors.affiliation: Dutch Society for Surgeons, Postbox 20061, 3502 LB Utrecht, The Netherlands. o.brook@nvvh.knmg.nl
authors.forename: Oscar Hugo
authors.initials: OH
authors.lastname: Brook
authors.forename: Hein
authors.initials: H
authors.lastname: van Hout
authors.forename: Wim
authors.initials: W
authors.lastname: Stalman
authors.forename: Hugo
authors.initials: H
authors.lastname: Nieuwenhuyse
authors.forename: Bram
authors.initials: B
authors.lastname: Bakker
authors.forename: Eibert
authors.initials: E
authors.lastname: Heerdink
authors.forename: Marten
authors.initials: M
authors.lastname: de Haan
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use*; D003863:Depression / Q000188:drug therapy* / Q000523:psychology; D004581:Electronics / Q000295:instrumentation; D005500:Follow-Up Studies; D006801:Humans; D010349:Patient Compliance; D010353:Patient Education as Topic; D010593:Pharmaceutical Services / Q000458:organization & administration*; D011320:Primary Health Care
chemical_list: D000928:Antidepressive Agents