title: [Costello syndrome. Presentation of a case with a follow-up of 35 years].
abstract: OBJECTIVE
  To present a patient of 35 years with Costello syndrome.
  
  
  METHODS
  A male consulted at 11 months of age because of psychomotor delay and peculiar face.
  
  
  RESULTS
  The main clinic features corresponded to the cutis laxa disease, although the picture and the results of the performed studies were not similar to any of the dysmorfic recognized syndromes.
  
  
  CONCLUSIONS
  The follow-up of the patient during 35 years showed a long survival, despite the cardiopathy, although he has a severe psychic retardation, showed very low height and weight centiles, and very high head circumference centiles.
authors.affiliation: Servicio de Neurología Pediátrica, Hospital Universitario La Paz, Madrid, Spain. pascas@inves.es
authors.forename: I
authors.initials: I
authors.lastname: Pascual-Castroviejo
authors.forename: Si
authors.initials: S
authors.lastname: Pascual-Pascual
mesh_terms: D000015:Abnormalities, Multiple; D000328:Adult; D001842:Bone and Bones / Q000002:abnormalities*; D005145:Face / Q000002:abnormalities*; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008607:Intellectual Disability; D008297:Male; D012868:Skin Abnormalities; D013577:Syndrome; D013997:Time Factors