title: Geographical distribution of congenital heart defects in Saudi Arabia.
abstract: BACKGROUND
  Congenital heart defects (CHD), which are caused by abnormalities early in fetal life, encompass over 50 diagnoses. Since the detailed etiology is unknown, the geographical distribution of defects might suggest likely risk factors.
  
  
  METHODS
  The geographical distribution of 5 865 Saudi Arabian nationals with CHD was studied by cross-matching their residential provinces and towns with a geographical information system provided by the General Directorate for Military Survey. Population data were obtained from the 1413H census.
  
  
  RESULTS
  CHD cases were mostly distributed across the provinces in proportion to their total population but due to their size and inhomogeneity, province-based thematic maps were found to be misleading. City-based maps were preferable and showed similar geographic distributions for cases registered in successive years. Thematic maps of the distribution of the CHD burden highlighted the southwestern provinces, nearthe border with Yemen, and the northeast section of the Eastern Province.
  
  
  CONCLUSIONS
  Patterns of disease in Saudi Arabia are best studied at the level of individual towns and villages. The CHD registry has already attained good national coverage and can therefore support nationwide epidemiological studies. Southwestern Saudi Arabia and the northern part of the Eastern Province appear to exhibit a higher burden of CHD.
authors.affiliation: Biostatistics, Epidemiology and Scientific Computing Department, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia. greer@kfshrc.edu.sa
authors.forename: W
authors.initials: W
authors.lastname: Greer
authors.forename: A L
authors.initials: AL
authors.lastname: Sandridge
authors.forename: M
authors.initials: M
authors.lastname: Al-Menieir
authors.forename: A
authors.initials: A
authors.lastname: Al Rowais
mesh_terms: D006330:Heart Defects, Congenital / Q000453:epidemiology*; D006801:Humans; D012529:Saudi Arabia / Q000453:epidemiology