title: [1/1 nodo-ventricular conduction atrial flutter with amiodarone].
abstract: 1/1 atrial flutter is a regularly described complication of class I anti-arrhythmics. It is, however, very rarely encountered with class III anti-arrhythmics because prolongation of the atrio-ventricular node refractory period prevents 1/1 nodo-ventricular conduction. There have only been seven cases of 1/1 atrial flutter with amiodarone reported in the literature. Here we describe a new case of 1/1 atrial flutter with amiodarone. Our case clearly illustrates not only the different pro-arrhythmic effects of amiodarone (prolongation of the flutter cycle, and infra-Hissian block) but also the pathophysiological mechanisms possible with 1/1 conduction (prolongation of the flutter cycle, considerable permeability of the AV node). It demonstrates the difficulties of diagnosing such a rhythm disturbance, and that it is sometimes poorly tolerated, as well as underlining the importance of early diagnosis (in this case by oesophageal recording). Preventive treatment of 1/1 flutter can include amiodarone, digitalis, a betablocker or a bradycardic calcium inhibitor.
authors.affiliation: Services de Cardiologie, HEGP, rue Leblanc, Paris
authors.forename: L
authors.initials: L
authors.lastname: Perdrix-Andujar
authors.forename: O
authors.initials: O
authors.lastname: Paziaud
authors.forename: G
authors.initials: G
authors.lastname: Ricard
authors.forename: B
authors.initials: B
authors.lastname: Diebold
authors.forename: J Y
authors.initials: JY
authors.lastname: Le Heuzey
mesh_terms: D000368:Aged; D000638:Amiodarone / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D001282:Atrial Flutter / Q000139:chemically induced* / Q000503:physiopathology; D001283:Atrioventricular Node / Q000503:physiopathology; D006329:Heart Conduction System / Q000503:physiopathology; D006801:Humans; D008297:Male
chemical_list: D000889:Anti-Arrhythmia Agents; D000638:Amiodarone