title: Dizygotic twin pregnancy conceived with assisted reproductive technology associated with chromosomal anomaly, imprinting disorder, and monochorionic placentation.
abstract: Assisted reproductive technology (ART) has now become a cornerstone of treatment for involuntary infertility. Recent studies have raised concern regarding potential associations between ART and chromosomal aneuploidy, imprinting anomalies, and monochorionic placentation in dizygotic (DZ) twins. We report a case of DZ twins conceived by ART in which all three problems coexist.
authors.affiliation: Department of Pediatrics, Division of Medical Genetics, University of California-San Francisco, San Francisco, CA, USA.
authors.forename: Grace
authors.initials: G
authors.lastname: Yoon
authors.forename: Linda S
authors.initials: LS
authors.lastname: Beischel
authors.forename: John P
authors.initials: JP
authors.lastname: Johnson
authors.forename: Marilyn C
authors.initials: MC
authors.lastname: Jones
mesh_terms: D001506:Beckwith-Wiedemann Syndrome / Q000209:etiology* / Q000235:genetics; D002823:Chorion; D002869:Chromosome Aberrations; D004200:Diseases in Twins / Q000209:etiology* / Q000235:genetics; D018392:Genomic Imprinting; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010920:Placenta; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects*; D014429:Twins, Dizygotic