title: [Changes of serum epithelial neutrophil-activating peptide-78 in patients with endometriosis].
abstract: OBJECTIVE
  To investigate the role of serum epithelial neutrophil-activating peptide-78 (ENA-78) in the pathogenesis of endometriosis.
  
  
  METHODS
  Serum concentrations of ENA-78 were measured by means of enzyme-linked immunosorbent assay (ELISA) in 42 patients with endometriosis (20 in stages I and II and 22 in stages III and IV) in comparison with 25 women without endometriosis (control group).
  
  
  RESULTS
  Serum concentrations of ENA-78 were significantly higher in endometriosis group than in the control group (2.97+/-1.91 ng/ml vs 0.72+/-0.24 ng/ml, P>0.001), and ENA-78 levels in stages III and IV were significantly higher than those in stages I and II (4.48+/-1.25 ng/ml vs 1.30+/-0.74 ng/ml, P>0.001). Significant difference in ENA-78 levels between follicular phase and luteal phase was found in neither of the groups.
  
  
  CONCLUSIONS
  Patients with endometriosis have elevated serum ENA-78 levels, which might be a pathogenic factor of endometriosis.
authors.affiliation: Department of Obstetrics and Gynecology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. caizhua12@hotmail.com
authors.forename: Zhu-Hua
authors.initials: ZH
authors.lastname: Cai
authors.forename: Yuan-Li
authors.initials: YL
authors.lastname: He
authors.forename: Dong-Xian
authors.initials: DX
authors.lastname: Peng
mesh_terms: D000328:Adult; D054365:Chemokine CXCL5; D019743:Chemokines, CXC / Q000097:blood*; D004715:Endometriosis / Q000097:blood*; D005260:Female; D006801:Humans; D008875:Middle Aged
chemical_list: C486263:CXCL5 protein, human; D054365:Chemokine CXCL5; D019743:Chemokines, CXC