[The expression of the estrogen receptor within the mammary gland of the breast hypertrophy and hypogenesis].
OBJECTIVE
To investigate the expression of the estrogen receptors(ER) in breast hypertrophy and micromastia.


METHODS
The quantity of ER within breast tissue in 13 patients with mammary hypertrophy strictly elected was determined using DCC single dot test. The results were compared with that measured in 13 patients with micromastia.


RESULTS
The average of the quantity of the ER was respectively (5.33 +/- 5.70) fmol/mg and (1.17 +/- 0.86) fmol/mg in mammary hypertrophy ground and in the micromastia group. There was obvious significant between the two groups in a statistics basis (P < 0.05) .


CONCLUSIONS
The breast hypertrophy is related to the excessive expression of ER within breast tissue,while the micromastia and breast hypotrophy are related to the lower level or the expression inhibition of ER.
Sun
Jia-ming
JM
Department of Plastic Surgery, Union Hospital of Tongji Medical College, Huazhong Science and Technology University, Wuhan 430022, China.
Qiao
Qun
Q
Qi
Ke-ming
KM
D000293:Adolescent; D000328:Adult; D001940:Breast / Q000002:abnormalities / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000378:metabolism* / Q000473:pathology; D008875:Middle Aged; D011960:Receptors, Estrogen / Q000378:metabolism*; D055815:Young Adult
D011960:Receptors, Estrogen