Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells.
Gnecchi
Massimiliano
M
He
Huamei
H
Liang
Olin D
OD
Melo
Luis G
LG
Morello
Fulvio
F
Mu
Hui
H
Noiseux
Nicolas
N
Zhang
Lunan
L
Pratt
Richard E
RE
Ingwall
Joanne S
JS
Dzau
Victor J
VJ
D000818:Animals; D017209:Apoptosis; D016026:Bone Marrow Transplantation; D015687:Cell Hypoxia; D002478:Cells, Cultured; D017077:Culture Media, Conditioned; D049452:Green Fluorescent Proteins / Q000494:pharmacology; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism*; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000378:metabolism*; D009203:Myocardial Infarction / Q000188:drug therapy; D009206:Myocardium / Q000166:cytology*; D017346:Protein Serine-Threonine Kinases / Q000235:genetics*; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D051057:Proto-Oncogene Proteins c-akt; D051381:Rats
D017077:Culture Media, Conditioned; D036341:Intercellular Signaling Peptides and Proteins; D011518:Proto-Oncogene Proteins; D049452:Green Fluorescent Proteins; C494920:Akt1 protein, rat; D017346:Protein Serine-Threonine Kinases; D051057:Proto-Oncogene Proteins c-akt