title: Neurons in macaque area V4 acquire directional tuning after adaptation to motion stimuli.
abstract: Neurons in area V4 of the macaque are generally not selective for direction of motion, as judged from their response to directional stimuli presented after a baseline condition devoid of movement. We used motion adaptation to investigate whether stimulation history influences direction-of-motion selectivity. We found that classically nondirectional V4 neurons develop direction-of-motion selectivity after adaptation, an observation that underscores the dynamic nature of functional cortical architecture.
authors.affiliation: Max Planck Institute for Biological Cybernetics, Spemannstrasse 38, Tuebingen, Germany. andreas.tolias@tuebingen.mpg.de
authors.forename: Andreas S
authors.initials: AS
authors.lastname: Tolias
authors.forename: Georgios A
authors.initials: GA
authors.lastname: Keliris
authors.forename: Stelios M
authors.initials: SM
authors.lastname: Smirnakis
authors.forename: Nikos K
authors.initials: NK
authors.lastname: Logothetis
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000222:Adaptation, Physiological / Q000502:physiology*; D000818:Animals; D001288:Attention / Q000502:physiology; D005133:Eye Movements / Q000502:physiology; D008253:Macaca mulatta; D009039:Motion Perception / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D010775:Photic Stimulation; D014793:Visual Cortex / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology