title: Identification and characterization of genes required for competence in Neisseria meningitidis.
abstract: We have identified genes required for competence of Neisseria meningitidis, a naturally transformable human pathogen. Although not comprehensive, our analysis identified competence-defective mutants with transposon insertions in genes not previously implicated in this process in Neisseria.
authors.affiliation: Centre for Molecular Microiology and Infection, Department of Infectious Diseases, Faculty of Medicine, Armstrong Road, Imperial College London, London SW7 2AZ, UK.
authors.forename: Yao-Hui
authors.initials: YH
authors.lastname: Sun
authors.forename: Rachel
authors.initials: R
authors.lastname: Exley
authors.forename: Yanwen
authors.initials: Y
authors.lastname: Li
authors.forename: David
authors.initials: D
authors.lastname: Goulding
authors.forename: Christoph
authors.initials: C
authors.lastname: Tang
mesh_terms: D004265:DNA Helicases / Q000235:genetics; D004251:DNA Transposable Elements / Q000235:genetics; D010861:Fimbriae, Bacterial / Q000235:genetics; D005798:Genes, Bacterial; D020043:Genes, Essential; D009154:Mutation; D009345:Neisseria meningitidis / Q000235:genetics* / Q000502:physiology; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System / Q000235:genetics; D017852:Phosphotransferases (Nitrogenous Group Acceptor) / Q000235:genetics; D014158:Transcription, Genetic; D014169:Transformation, Bacterial / Q000235:genetics*
chemical_list: D004251:DNA Transposable Elements; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System; D017852:Phosphotransferases (Nitrogenous Group Acceptor); C022360:phosphoenolpyruvate-protein phosphotransferase; D004265:DNA Helicases