Bacterial mitosis: actin in a new role at the origin.
MreB is a prokaryotic homolog of actin involved in cellular organization and chromosome segregation. Recent results suggest that MreB is part of a kinetochore-like complex that specifically segregates the replication origin region of the bacterial chromosome.
Margolin
William
W
Department of Microbiology and Molecular Genetics, University of Texas Medical School, Houston, Texas 77030, USA. William.Margolin@uth.tmc.edu <William.Margolin@uth.tmc.edu>
D000199:Actins / Q000235:genetics / Q000502:physiology*; D001419:Bacteria / Q000235:genetics*; D020090:Chromosome Segregation / Q000502:physiology*; D029968:Escherichia coli Proteins / Q000235:genetics / Q000502:physiology*; D018386:Kinetochores / Q000502:physiology*; D008938:Mitosis / Q000502:physiology*; D008954:Models, Biological; D018741:Replication Origin / Q000502:physiology
D000199:Actins; D029968:Escherichia coli Proteins; C078473:MreB protein, E coli