title: Spectral characteristics of the supramolecular complexes of polypyrrolic sensitizers and cyclodextrin carriers: usage in photodynamic therapy of tumors.
abstract: The objective of our work was to describe the photophysical properties (absorption and fluorescence) of the sensitizers TPPS4, ZnTPPS4 a PdTPPS4 and above all the complexes of these sensitizers with cyclodextrin carriers HP-alpha-CD, HP-beta-CD and HP-gamma-CD (2-hydroxypropyl-alpha, beta, gamma-cyclodextrin) in a suitable environment for the cultivation of cancerous cell lines, and to determine the optimal radioactive conditions for maximizing photodynamic effects in cancerous cells.
authors.affiliation: Palacky University Olomouc, Faculty of Medicine, Institute of Medical Biophysics, Czech Republic. m.huf@seznam.cz
authors.forename: Martin
authors.initials: M
authors.lastname: Huf
authors.forename: Hana
authors.initials: H
authors.lastname: Kolárová
authors.forename: Robert
authors.initials: R
authors.lastname: Bajgar
authors.forename: Jaroslav
authors.initials: J
authors.lastname: Macecek
authors.forename: Marek
authors.initials: M
authors.lastname: Tomecka
authors.forename: Pavla
authors.initials: P
authors.lastname: Nevrelová
authors.forename: Jirí
authors.initials: J
authors.lastname: Mosinger
authors.forename: Pavel
authors.initials: P
authors.lastname: Tomek
authors.forename: Miroslav
authors.initials: M
authors.lastname: Strnad
mesh_terms: D003505:Cyclodextrins / Q000737:chemistry*; D004337:Drug Carriers / Q000737:chemistry*; D009369:Neoplasms / Q000188:drug therapy; D010777:Photochemistry; D010778:Photochemotherapy; D011108:Polymers / Q000737:chemistry; D011166:Porphyrins / Q000737:chemistry; D011758:Pyrroles / Q000737:chemistry; D011838:Radiation-Sensitizing Agents / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013053:Spectrophotometry
chemical_list: D003505:Cyclodextrins; D004337:Drug Carriers; D011108:Polymers; D011166:Porphyrins; D011758:Pyrroles; D011838:Radiation-Sensitizing Agents; C067635:polypyrrole