[Eosinophilic oesophagitis in young men with food swallowing complaints].
Three men, aged 20, 24 and 42 years, reported difficulties in passing food through the oesophagus. The diagnosis of eosinophilic oesophagitis was made after endoscopic investigation, laboratory tests and histological tests. In all three patients the symptoms disappeared: respectively spontaneously, during systemic treatment with corticosteroids due to a kidney complaint, and after topical corticosteroid treatment lasting 6 weeks. Eosinophilic oesophagitis occurs in particular in young men. There are complaints about the passage of food through the oesophagus, with frequent food impaction, also without any obvious stenosis. Endoscopic features are subtle and comprise a vulnerable oesophageal mucosa with a ringed appearance or small white spots on the oesophageal mucosa. Histopathology reveals an eosinophilic infection infiltrate in the oesophageal epithelium. Food allergies may play a causal role. With respect to the treatment, favourable results have been described for oral fluticasone, while endoscopic treatment may consist of dilation.
Thijs
W J
WJ
Afd. Maag-, Darm- en Leverziekten, Universitair Medisch Centrum Groningen, Postbus 30.001, 9700 RB Groningen.
Koornstra
J J
JJ
Karrenbeld
A
A
Limburg
A J
AJ
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000730:Androstadienes / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003680:Deglutition Disorders / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D004802:Eosinophilia / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D004941:Esophagitis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D000068298:Fluticasone; D006801:Humans; D008297:Male; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones; D000730:Androstadienes; D000893:Anti-Inflammatory Agents; D000068298:Fluticasone