Mutation in cGMP-dependent protein kinase II causes dwarfism in a rat mutant KMI through uncoupling of proliferation and differentiation of chondrocytes.
Chikuda
Hirotaka
H
Department of Sensory and Motor System Medicine, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. chikuda-tky@umin.ac.jp
Kugimiya
Fumitaka
F
Hoshi
Kazuto
K
Ikeda
Toshiyuki
T
Ogasawara
Toru
T
Kamekura
Satoru
S
Ogata
Naoshi
N
Nakamura
Kozo
K
Chung
Ung-Il
UI
Kawaguchi
Hiroshi
H
D000818:Animals; D001846:Bone Development; D002454:Cell Differentiation; D049109:Cell Proliferation; D019902:Chondrocytes / Q000473:pathology*; D062967:Cyclic GMP-Dependent Protein Kinase Type II; D017869:Cyclic GMP-Dependent Protein Kinases / Q000235:genetics*; D004392:Dwarfism / Q000235:genetics* / Q000473:pathology; D006132:Growth Plate / Q000473:pathology; D006609:High Mobility Group Proteins / Q000235:genetics; D009154:Mutation; D051381:Rats; D055758:SOX9 Transcription Factor; D015398:Signal Transduction; D014157:Transcription Factors / Q000235:genetics
D006609:High Mobility Group Proteins; D055758:SOX9 Transcription Factor; D014157:Transcription Factors; D062967:Cyclic GMP-Dependent Protein Kinase Type II; D017869:Cyclic GMP-Dependent Protein Kinases; C569732:Prkg2 protein, rat