Characterization of a Bacillus anthracis isolate causing a rare case of fatal anthrax in a 2-year-old boy from Hong Kong.
We used multiple-locus variable-number tandem repeat analysis (MLVA) and pagA sequencing to genotype a Bacillus anthracis isolate from a fatal case of human anthrax in Hong Kong. The isolate has a unique MLVA genotype, is related to the Sterne and Ames strains, and is consistent with genotypes identified in China.
Cheung
Danny T L
DT
Department of Health, Hong Kong Special Administrative Region, Hong Kong, China.
Kam
Kai Man
KM
Hau
Kong Lung
KL
Au
Tak Kong
TK
Marston
Chung K
CK
Gee
Jay E
JE
Popovic
Tanja
T
Van Ert
Matthew N
MN
Kenefic
Leo
L
Keim
Paul
P
Hoffmaster
Alex R
AR
D000881:Anthrax / Q000382:microbiology*; D000942:Antigens, Bacterial / Q000235:genetics*; D001408:Bacillus anthracis / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D001427:Bacterial Toxins / Q000235:genetics*; D015373:Bacterial Typing Techniques; D017809:Fatal Outcome; D005838:Genotype; D006723:Hong Kong; D006801:Humans; D008297:Male; D018598:Minisatellite Repeats / Q000235:genetics*; D017422:Sequence Analysis, DNA
D000942:Antigens, Bacterial; D001427:Bacterial Toxins; C030325:anthrax toxin