Mineralization mechanism of calcium phosphates under three kinds of Langmuir monolayers.
Three kinds of Langmuir monolayers formed by dipalmitoylphosphatidylcholine (DPPC), arachidic acid (AA), and octadecylamine (ODA) were used as templates to study the initial stage of nucleation and crystallization of calcium phosphates. It was demonstrated that the combination of calcium ions (or phosphates) to the monolayer/subphase interface is a prerequisite for subsequent nucleation. It was found that calcium phosphate dihydrate (DPCD) formed at 25.0 degrees C for 12 h has a biphasic structure containing both amorphous and crystalline phases. These results showed that calcium phosphates were formed through a multistage assembly process, during which an initial amorphous phase DPCD was followed by a phase transformation into a crystalline phase and then the most stable hydroxyapatite (HAp). This provided new insights into the template-biomineral interaction and a mechanism for biomineralization.
Zhang
Li-Juan
LJ
Key Laboratory of Colloid and Interface Chemistry (Shandong University), Ministry of Education, Jinan 250100, People's Republic of China.
Liu
Hong-Guo
HG
Feng
Xu-Sheng
XS
Zhang
Ren-Jie
RJ
Zhang
Li
L
Mu
Ying-Di
YD
Hao
Jing-Cheng
JC
Qian
Dong-Jin
DJ
Lou
Yu-Feng
YF