[Seasonal changes of the activity of calcium-transporting systems in the heart and skeletal muscles of hibernating animals].
In a short review of literature and according to our own data the molecular mechanisms providing seasonal adjustments of the activity of membrane Ca-transporting systems (Ca-channels and Ca-pumps) in muscle tissues of animals which spent winter time in a deep torpor state (hibernation), were analyzed. Special attention was paid to changes of protein composition of sarcoplasmic reticulum membranes--the key intracellular structure responsible for excitation-contraction coupling in different types of muscles, as well as to participation of endogenous protein kinases in regulation of functional activity of plasma membrane Ca-channels and sarcoplasmic reticulum Ca-ATPase during hibernation.
Rubtsov
A M
AM
D000818:Animals; D001692:Biological Transport; D002118:Calcium / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism* / Q000502:physiology; D006321:Heart / Q000502:physiology; D006605:Hibernation / Q000502:physiology*; D018482:Muscle, Skeletal / Q000166:cytology / Q000378:metabolism* / Q000502:physiology; D009206:Myocardium / Q000166:cytology / Q000378:metabolism*; D012621:Seasons
D002118:Calcium