A computational view of microRNAs and their targets.
Small non-coding RNAs called microRNAs have been shown to play important roles in gene regulation across a broad range of metazoans from plants to humans. In this review, the nature and function of microRNAs will be discussed, with special emphasis on the computational tools and databases available to predict microRNAs and the genes they target.
Brown
James R
JR
GlaxoSmithKline, Bioinformatics Discovery and Analysis, Upper Providence, 1250 South Collegeville Road, UP1345, PO Box 5089, Collegeville, PA 19426-0989, USA.
Sanseau
Philippe
P
D000818:Animals; D018390:Gene Targeting / Q000379:methods* / Q000639:trends; D006801:Humans; D035683:MicroRNAs / Q000494:pharmacology* / Q000502:physiology*; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods
D035683:MicroRNAs