[New therapeutic strategies in bronchial asthma].
Bronchial asthma becomes one of the most frequent respiratory diseases of the childhood. Progresses of the last decade did not interfere with long term prognosis of the disease. New therapeutic researches try to stop the chronic inflammatory respiratory mechanism: cytokines, leukotrienes, transcription factors, IgE. Some of the new drugs are still only experimental--cytokines antagonists, transcription factors inhibitors, adhesin antibodies, other close to clinical use--new corticosteroids, leukotrienes antagonists, anti IgE antibodies. The new therapeutics methods will be used among the classical drugs and will improve the quality of the patients' life.
Goţia
Stela
S
Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină, Clinica II Pediatrie.
Hermeziu
B
B
D018927:Anti-Asthmatic Agents / Q000494:pharmacology / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy* / Q000378:metabolism; D018925:Chemokines / Q000037:antagonists & inhibitors / Q000627:therapeutic use; D016207:Cytokines / Q000037:antagonists & inhibitors / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D015289:Leukotrienes / Q000378:metabolism; D011788:Quality of Life; D019087:Selectins / Q000378:metabolism
D018927:Anti-Asthmatic Agents; D000893:Anti-Inflammatory Agents; D018925:Chemokines; D016207:Cytokines; D015289:Leukotrienes; D019087:Selectins