title: [Age-dependent dynamics of the rib and tibial microstructures].
abstract: The purpose of the present work was the detailed study of peculiarities of the bone tissue age changes. The samples of the bone tissue of the third left rib (taken from the zone of osseo-cartilagenous transition), as well as the distal epiphysis and diaphysis of the left tibia were used as a material for this research. The samples were obtained from 364 male cadavers of the persons aged 0 to 90 years. As a result of this study, the dynamics of bone features that were most age-dependent was described, and their quantitative characteristics were determined. The conception is formulated, according to which bone age involution should be regarded as an ultimate result of accumulation of residual phenomena of its physiological regeneration cycles, former injuries and progressing pathological processes leading to the gradual reduction of the structural orderliness of the tissue.
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Pigolkin
authors.forename: M V
authors.initials: MV
authors.lastname: Fedulova
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001846:Bone Development; D001862:Bone Resorption / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000473:pathology; D012272:Ribs / Q000033:anatomy & histology*; D013977:Tibia / Q000033:anatomy & histology*