Successful treatment of cerebral blastomycosis with voriconazole.
Blastomycosis can occasionally involve the central nervous system (CNS). Amphotericin B deoxycholate is considered the drug of choice for the treatment of CNS blastomycosis. Significant toxicity may be associated with its use. We describe a case of cerebral blastomycoma that was successfully treated with voriconazole.
Bakleh
Mohanad
M
Division of Infectious Diseases, Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA. mohanadbakleh@yahoo.com
Aksamit
Allen J
AJ
Tleyjeh
Imad M
IM
Marshall
William F
WF
D000935:Antifungal Agents / Q000627:therapeutic use*; D001759:Blastomycosis / Q000188:drug therapy*; D001927:Brain Diseases / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011743:Pyrimidines / Q000627:therapeutic use*; D014230:Triazoles / Q000627:therapeutic use*; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole