title: Minimally invasive optimization of organ donor resuscitation: case reports.
abstract: Increased use of expanded donors requires optimal organ perfusion to prevent graft damage. In this regard, pulmonary artery catheters have been advocated to monitor hemodynamic status. Cost, catheter placement, and inconsistent management preclude broad use of pulmonary artery catheters. Esophageal Doppler monitoring also monitors hemodynamic status and can be instituted in minutes by an organ procurement coordinator, Concomitant assessment of acid-base balance using base excess and/or anion gap can help determine resuscitation efficacy. Esophageal Doppler monitoring is described to help salvage 2 hemodynamically deteriorating donors. Anion gap and corrected base excess identified poor resuscitation status in both donors and normalized after improvement in hemodynamic status. Compared to pulmonary artery catheters, esophageal Doppler monitoring may provide a more accessible means to assess and improve hemodynamic status. Base deficit and/or anion gap may determine resuscitation efficacy by exposing acid-base imbalance resulting from poor tissue perfusion. The full efficacy of this approach remains to be determined.
authors.affiliation: New Jersey Medical School, Newark, NJ, USA.
authors.forename: Andrew N
authors.initials: AN
authors.lastname: de la Torre
authors.forename: Adrian
authors.initials: A
authors.lastname: Fisher
authors.forename: Dorian J
authors.initials: DJ
authors.lastname: Wilson
authors.forename: William
authors.initials: W
authors.lastname: Reitsma
authors.forename: Frederick
authors.initials: F
authors.lastname: Goerlitz
authors.forename: Baburao
authors.initials: B
authors.lastname: Koneru
mesh_terms: D000328:Adult; D017548:Echocardiography, Transesophageal; D005260:Female; D006801:Humans; D008875:Middle Aged; D008991:Monitoring, Physiologic; D016377:Organ Transplantation; D012151:Resuscitation / Q000379:methods*; D014019:Tissue Donors; D020858:Tissue and Organ Harvesting / Q000379:methods*