title: Obsessive-compulsive symptoms in clozapine-treated schizophrenic patients.
abstract: The aim of the present study was to assess the occurrence of obsessive-compulsive symptoms (OCS) in schizophrenic patients treated with clozapine, and to examine the relationship between OCS and other clinical variables. The results support earlier findings which suggest that clozapine produces or unmasks OCS. In addition, the severity of OCS was not related to other dimensions of psychopathology, severity of illness, clinical improvement or dose and duration of clozapine treatment.
authors.affiliation: Hacettepe University Faculty of Medicine, Department of Psychiatry, Ankara 06100, Turkey. aertugru@hacettepe.edu.tr
authors.forename: Aygun
authors.initials: A
authors.lastname: Ertugrul
authors.forename: A Elif
authors.initials: AE
authors.lastname: Anil Yagcioglu
authors.forename: Nurhayat
authors.initials: N
authors.lastname: Eni
authors.forename: Kâzim M
authors.initials: KM
authors.lastname: Yazici
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D003024:Clozapine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000150:complications* / Q000188:drug therapy* / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000150:complications* / Q000188:drug therapy*; D012565:Schizophrenic Psychology; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use
chemical_list: D014150:Antipsychotic Agents; D003024:Clozapine; D017367:Selective Serotonin Reuptake Inhibitors