title: Stress reactivity and family relationships in the development and treatment of endometriosis.
abstract: OBJECTIVE
  To examine stress physiology and facts of family functioning associated with development and course of endometriosis symptoms.
  
  
  METHODS
  Clinical case data and literature review.
  
  
  METHODS
  Private practice in hospital-affiliated medical office.
  
  
  METHODS
  One woman with endometriosis, her parents, and a nonsymptomatic volunteer.
  
  
  METHODS
  Measures of physiologic and neural reactivity with biofeedback and neurofeedback equipment during family history interview and while sitting quietly.
  
  
  METHODS
  Electroencephalography (EEG), digital skin temperature (DST), electrodermal response (EDR), and electromyography (EMG); facts of family history; contact with family.
  
  
  RESULTS
  Endometriosis symptoms were associated with DST, EDR, EMG, and EEG measures indicating prolonged stress reactions for the symptomatic woman and her parents. Facts of family history and relationships for three generations set the stage for stress reactions. Striking differences are evident in the physiology, family history, and contact with family of the nonsymptomatic woman.
  
  
  CONCLUSIONS
  Differences warrant further study, a larger sample, and additional measures using hormone assay to establish connections between stress reactions in the family, endometriosis symptoms, and response to treatment. Further research will document changes in physiology and in symptoms that accompany interruption of stress reactions with self-regulation training and family systems psychotherapy.
authors.affiliation: Family Health Services and Center for the Study of Natural Systems and the Family, Woman's Hospital of Texas, 7580 Fannin, Houston, TX 77054, USA. vichar@worldnet.att.net
authors.forename: Victoria
authors.initials: V
authors.lastname: Harrison
authors.forename: Karen
authors.initials: K
authors.lastname: Rowan
authors.forename: John
authors.initials: J
authors.lastname: Mathias
mesh_terms: D000293:Adolescent; D001676:Biofeedback, Psychology; D004569:Electroencephalography; D004715:Endometriosis / Q000150:complications / Q000503:physiopathology / Q000523:psychology; D005190:Family; D005191:Family Characteristics; D005260:Female; D006801:Humans; D013315:Stress, Psychological / Q000150:complications* / Q000503:physiopathology*