[The effect of ampicillin on the electrophysical properties of Escherichia coli cells].
The study of the effect of ampicillin on the electrophysical properties of Escherichia coli cells showed that this antibiotic influences the orientational spectra (OS) of the ampicillin-susceptible E. coli strains K-12 and XL-1 within the frequency range 10-1000 kHz of the orienting electric field and does not affect the OS of the ampicillin-resistant strains K-12(pUC-18) and XL-1(pHEN1). The change in the electrooptical signal of the ampicillin-susceptible cells was maximum at an ampicillin concentration of 50 microg/ml and did not depend on the exposure time. The conclusion is drawn that changes in the OS of cells can be used to evaluate their resistance to ampicillin.
Guliĭ
O I
OI
Markina
L N
LN
Ignatov
O V
OV
Shchegolev
S Iu
SIu
Zaĭtseva
I S
IS
Bunin
V D
VD
Ignatov
V V
VV
D000667:Ampicillin / Q000494:pharmacology*; D000668:Ampicillin Resistance; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004574:Electromagnetic Fields; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects* / Q000502:physiology*; D013057:Spectrum Analysis
D000900:Anti-Bacterial Agents; D000667:Ampicillin