title: [Comparative evaluation of the toxicity induced by mussels (Mytilus galloprovincialis) from two sites of the Moroccan Atlantic coast in mice].
abstract: Atlantic coast in mice. Preliminary studies showed that seawater contains heavy metals from domestic, agricultural and industrial wastes. Marine bivalves concentrate these pollutants by filtration and serve as vectors in human exposure. The objective of this study was to determine the concentration of heavy metals; cadmium (Cd); chromium (Cr), and lead (Pb) in mussels (Mytilus galloprovincialis) collected in two coastal sites; Jorf Lasfar (JL) (neighbouring a phosphate processing platform) and Oualidia (OL) (a vegetable growing area) located at 120 and 190 km south of Casablanca, respectively. Another objective was to test and compare the toxicity of these mussels on mice. The results indicated the presence of heavy metals (Cd, Cr, and Pb) in mussels at different concentrations, depending on the collection period. Higher concentrations were obtained at JL than at OL: for example, Cd concentrations were 80 +/- 15 to 199 +/- 28 versus 23 +/- 5 microg/g mussel dry weight, respectively. Cramming with mussel powder did not increase Cd, Cr, or Pb concentration in either liver or kidneys of treated mice. The relative kidney weights were reduced. Increased glucose urea was observed in animals' urine. Treatment with mussels from OL induced significant reduction (20%) in mice body weight, together with an increase in creatinuria. These results indicate that mussels collected from OL are more harmful than those obtained from JL are. All these mussels should not be recommended for human consumption.
authors.affiliation: Laboratoire de Chimie Organique, Faculté des Sciences, BP 4010, Beni M'hamed, Meknès, Maroc.
authors.forename: Khadija
authors.initials: K
authors.lastname: Moustaid
authors.forename: Boubker
authors.initials: B
authors.lastname: Nasser
authors.forename: Isabelle
authors.initials: I
authors.lastname: Baudrimont
authors.forename: Rachid
authors.initials: R
authors.lastname: Anane
authors.forename: Mostafa
authors.initials: M
authors.lastname: El Idrissi
authors.forename: Abdelhamid
authors.initials: A
authors.lastname: Bouzidi
authors.forename: Edmond E
authors.initials: EE
authors.lastname: Creppy
mesh_terms: D000818:Animals; D049872:Bivalvia; D008297:Male; D008387:Marine Toxins / Q000633:toxicity*; D051379:Mice; D009018:Morocco
chemical_list: D008387:Marine Toxins