Periodic fever syndromes.
Human autoinflammatory diseases (except for the periodic fever, adenopathy, pharyngitis, aphthae syndrom) are a heterogeneous group of genetically determined diseases characterized by seemingly unprovoked inflammation, in the absence of autoimmune or infective causes. Tremendous advances in the understanding of these disorders have been seen in the last decade. This article discusses hereditary autoinflammatory syndromes that are associated with recurrent fevers.
Padeh
Shai
S
Pediatric Rheumatology, Edmond & Lily Safra Children Hospital, The Chaim Sheba Medical Center, Tel Hashomer 52621, Israel. padeh@012.net.il
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003598:Cytoskeletal Proteins; D004252:DNA Mutational Analysis; D003937:Diagnosis, Differential; D010505:Familial Mediterranean Fever / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D005838:Genotype; D006801:Humans; D007223:Infant; D010641:Phenotype; D017354:Point Mutation / Q000235:genetics; D011506:Proteins / Q000235:genetics; D000071198:Pyrin
D003598:Cytoskeletal Proteins; D011506:Proteins; D000071198:Pyrin