[Effectiveness of ronkoleukin in children with reactive arthritis of chlamydial etiology].
14 children with reactive arthritis (ReA) were treated by antibiotics of macrolid group--vilprafen and anti-inflammatory medicines. Immunocorrective mean ronkoleukin (recombinant interleukin-2) was used as an additional therapy for activation of lymphocytes and NK cells. Five patients from 14 were treated by intravenous injections of ronkoleukin followed by oral administration of this drug. 9 children were treated by oral administration of ronkoleukin. All 14 children were treated by ronkoleukin along with the basic therapy. All children got repeated course of ronkoleukin one year later. From 14 children 12 reached remission of the disease.
Grigorashvili
M T
MT
Zhvaniia
M A
MA
D000284:Administration, Oral; D000293:Adolescent; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000032:analysis; D015703:Antigens, CD / Q000097:blood; D016918:Arthritis, Reactive / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D002690:Chlamydia Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007275:Injections, Intravenous; D007376:Interleukin-2 / Q000008:administration & dosage / Q000627:therapeutic use*; D000091402:Prohibitins; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000627:therapeutic use; D012074:Remission Induction; D013997:Time Factors; D016896:Treatment Outcome
D018712:Analgesics, Non-Narcotic; D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000907:Antibodies, Bacterial; D015703:Antigens, CD; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007376:Interleukin-2; C000717331:PHB2 protein, human; D000091402:Prohibitins; D011994:Recombinant Proteins