Structural details of rat extraocular muscles and three-dimensional reconstruction of the rat inferior rectus muscle and muscle-pulley interface.
Light microscopy, electron microscopy and morphometry revealed structural details and allowed generation of a three-dimensional reconstruction of the pulley and muscle-pulley interface of extraocular muscle. The inferior rectus orbital layer was bifurcate in shape and extended anterior to the pulley. The putative pulley structure itself was asymmetric; loosely attached at the orbital aspect it adhered tightly to the global aspect of muscle. Orbital multiply innervated fiber proportion increased anterior to the pulley insertion site. Additionally longitudinal variation in juxtaposition of orbital and global layers was noted. These newly described structural details provide novel mechanistic insight for extraocular muscle function in rats.
Felder
Edward
E
Department of Cell and Developmental Biology and Pennsylvania Muscle Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6085, USA.
Bogdanovich
Sasha
S
Rubinstein
Neal A
NA
Khurana
Tejvir S
TS
D000818:Animals; D003094:Collagen / Q000648:ultrastructure; D003238:Connective Tissue / Q000648:ultrastructure; D005133:Eye Movements / Q000502:physiology; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods; D008297:Male; D018485:Muscle Fibers, Skeletal / Q000648:ultrastructure; D009801:Oculomotor Muscles / Q000502:physiology / Q000648:ultrastructure*; D009915:Orbit / Q000648:ultrastructure; D051381:Rats; D017208:Rats, Wistar
D003094:Collagen