title: Mega-dose carbamazepine complicating third trimester of pregnancy.
abstract: A case of coma due to carbamazepine ingestion with the intention of committing suicide at 33 weeks' gestation is presented. Management included activated charcoal administration and exchange plasmapheresis. A fetal non-stress test was non-reassuring but the Apgar score, cord blood gases and early neonatal outcome were normal. Differential diagnosis of coma in pregnancy should include investigation for drug intoxication.
authors.affiliation: Department of Obstetrics and Gynecology, Hacettepe University School of Medicine, Ankara, Turkey.
authors.forename: Burcu
authors.initials: B
authors.lastname: Saygan-Karamursel
authors.forename: Suleyman
authors.initials: S
authors.lastname: Guven
authors.forename: Lutfi
authors.initials: L
authors.lastname: Onderoglu
authors.forename: Ozgur
authors.initials: O
authors.lastname: Deren
authors.forename: Tekin
authors.initials: T
authors.lastname: Durukan
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000097:blood / Q000633:toxicity*; D002220:Carbamazepine / Q000097:blood / Q000633:toxicity*; D015148:Cardiotocography; D003937:Diagnosis, Differential; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D006340:Heart Rate, Fetal; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications; D011263:Pregnancy Trimester, Third; D013406:Suicide, Attempted
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine