title: Surgical treatment of cerebellopontine angle meningiomas in elderly patients.
abstract: BACKGROUND
  The aim of this study is to assess the morbidity and mortality of meningioma surgery in patients over 70 years of age harbouring a tumour at the cerebellopontine angle as one representative location of the posterior fossa in comparison with a matched group of young patients.
  
  
  METHODS
  A retrospective analysis based on clinical charts, surgical records, histological records, imaging studies and follow up records was conducted to select patients over 70 years who underwent surgery for cerebellopontine angle meningiomas. Tumours with comparable size and location were matched with the younger group.
  
  
  RESULTS
  There were 421 meningiomas located in the cerebellopontine angle, 21 patients were older than 70 years (range 70-84). Median Karnofsky-Index at presentation was 80 (50-90), 16 patients had a physical status grading ASA 2 and 5 patients ASA 3. The average length of hospital stay was 22 days (7-99 days). The postoperative median Karnofsky score at time of discharge was 80 (50-90). The most common medical complication was postoperative pneumonia in 4 patients, among them 3 patients had lower cranial nerve disturbances postoperatively. There were 56 younger patients (mean age 52.4 years; range 24.5-69.75 years) with corresponding tumour size and location. Pre-op Karnofsky score was 80 (70-90), 53 patients were graded as ASA 2 and 3 patients as ASA 3. Length of hospital stay was 13.6 days (8-32 days). Post-op Karnofsky score was 80 (50-90). Among 5 patients with postoperative lower cranial nerve disturbances no patient had pneumonia postoperatively. There was no peri-operative mortality in either group.
  
  
  CONCLUSIONS
  With modern neurosurgical techniques and neuro-anesthesia elderly patients with CPA meningiomas can be operated on with acceptable low morbidity and good neurological outcome but recovery from surgery lasts longer compared to younger patients. However, postoperative lower cranial nerve deficits in elderly patients may not be well tolerated compared with younger patients.
authors.affiliation: Department of Neurosurgery, Nordstadt Hospital, Teaching Hospital Hannover Medical School, Hannover, Germany. mnakamura@web.de
authors.forename: M
authors.initials: M
authors.lastname: Nakamura
authors.forename: F
authors.initials: F
authors.lastname: Roser
authors.forename: M
authors.initials: M
authors.lastname: Dormiani
authors.forename: P
authors.initials: P
authors.lastname: Vorkapic
authors.forename: M
authors.initials: M
authors.lastname: Samii
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002528:Cerebellar Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D002530:Cerebellopontine Angle / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D017567:Karnofsky Performance Status; D008297:Male; D008579:Meningioma / Q000150:complications / Q000473:pathology / Q000601:surgery*; D008866:Microsurgery / Q000009:adverse effects* / Q000401:mortality; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000009:adverse effects* / Q000401:mortality; D012189:Retrospective Studies; D016896:Treatment Outcome