title: Severe anaphylactic reaction after intracameral antibiotic administration during cataract surgery.
abstract: We report a severe anaphylactic reaction that occurred about 5 minutes after 1.0 mg of cefuroxime was injected into the anterior chamber after routine phacoemulsification and intraocular lens implantation. The patient was known to be allergic to penicillin. Immediate action was taken, and the patient recovered well. The presence of staff trained in resuscitation was essential in this case and raises questions about the trend to perform routine topical anesthesia cataract surgery without an anesthesiologist in the operating room.
authors.affiliation: Clínica Oftalmológica Castilla-La Mancha, Alicante, Spain. jvillada@europhthalmics.com
authors.forename: José R
authors.initials: JR
authors.lastname: Villada
authors.forename: Ubaldo
authors.initials: U
authors.lastname: Vicente
authors.forename: Jaime
authors.initials: J
authors.lastname: Javaloy
authors.forename: Jorge L
authors.initials: JL
authors.lastname: Alió
mesh_terms: D000368:Aged; D000707:Anaphylaxis / Q000139:chemically induced* / Q000188:drug therapy; D000772:Anesthesia, Local; D000867:Anterior Chamber / Q000187:drug effects*; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002444:Cefuroxime / Q000009:adverse effects*; D002744:Chlorpheniramine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D019654:Lens Implantation, Intraocular; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D018918:Phacoemulsification; D011899:Ranitidine / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D006634:Histamine H1 Antagonists; D006635:Histamine H2 Antagonists; C018904:dexchlorpheniramine; D002744:Chlorpheniramine; D011899:Ranitidine; D002444:Cefuroxime; D008775:Methylprednisolone