title: [Prevalence of canine infection from endemic areas of American cutaneous leishmaniasis in Paracambi District, Rio de Janeiro State, between 1992 and 1993].
abstract: In the district of Paracambi, State of Rio de Janeiro an epidemiological survey for American tegumentary leishmaniasis in canine population was carried out in endemic localities. A total of 179 dogs was registered and 138 (77.1%) examined for their clinical aspects, development of delayed hypersensitivity (DHS) with Imunoleish(R) antigen and serological responses by indirect immunofluorescent reaction and enzyme-linked immunosorbent assay. In 9 (6.5%) dogs with active cutaneous lesions or suspect scars, 66.7% were caused by Leishmania sp; 44.4% produced infection in hamsters and showed growth in culture media, which was considered to be compatible with the species of Leishmania braziliensis complex. The molecular characterization (isoenzyme and KDNA restriction profiles) defined two strains with similar profiles for L. (Viannia) braziliensis. The prevalence of canine infection estimated by the cutaneous test, IFR and ELISA was 10.1%, 16.7% and 27.8%, respectively. The presence of clinical / sub-clinical form of ATL in canine population associated with human infections suggested that the dog can act as source of infection as well as for dissemination of the disease.
authors.affiliation: Serviço de Zoonoses, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil. ginelza@ipec.fiocruz.br
authors.forename: Ginelza Peres Lima
authors.initials: GP
authors.lastname: dos Santos
authors.forename: Argemiro
authors.initials: A
authors.lastname: Sanavria
authors.forename: Mauro Célio de Almeida
authors.initials: MC
authors.lastname: Marzochi
authors.forename: Elizabeth Glória Oliveira Barbosa
authors.initials: EG
authors.lastname: dos Santos
authors.forename: Valmir Laurentino
authors.initials: VL
authors.lastname: Silva
authors.forename: Raquel da Silva
authors.initials: Rda S
authors.lastname: Pacheco
authors.forename: Eliame
authors.initials: E
authors.lastname: Mouta-Confort
authors.forename: Cleber Barreto
authors.initials: CB
authors.lastname: Espíndola
authors.forename: Marcos Barbosa
authors.initials: MB
authors.lastname: de Souza
authors.forename: Cesar Santos
authors.initials: CS
authors.lastname: Ponte
authors.forename: Nilton Francisco
authors.initials: NF
authors.lastname: da Conceição
authors.forename: Moacir Vieira
authors.initials: MV
authors.lastname: de Andrade
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D001938:Brazil / Q000453:epidemiology; D006224:Cricetinae; D004283:Dog Diseases / Q000175:diagnosis / Q000453:epidemiology*; D004285:Dogs; D019353:Endemic Diseases; D005260:Female; D007891:Leishmania / Q000276:immunology*; D016773:Leishmaniasis, Cutaneous / Q000175:diagnosis / Q000453:epidemiology / Q000662:veterinary*; D008297:Male; D015995:Prevalence; D011576:Psychodidae; D012882:Skin Tests
chemical_list: D000913:Antibodies, Protozoan