title: Primary conjunctival sporotrichosis: two cases from a zoonotic epidemic in Rio de Janeiro, Brazil.
abstract: OBJECTIVE
  To describe Sporothrix schenckii conjunctivitis in 2 owners of cats with sporotrichosis.
  
  
  METHODS
  Small case series and literature review.
  
  
  RESULTS
  Two women had been caring for their pet cats with sporotrichosis for 2 months but did not recall any traumatic injury such as scratches or bites. Each presented a conjunctival granulomatous lesion measuring 4 to 5 mm accompanied by local hyperemia, secretion, and edema, in addition to painful facial subcutaneous nodes and regional lymph node enlargement. Pyogenic material was collected from the conjunctival sac and from cutaneous lesions on the cats. In both the patients and their respective cats, fungal colonies were isolated and identified as S. schenckii. Treatment with oral itraconazole 100 mg/d for 3 months resulted in complete healing of lesions in both patients. Patients remained clinically cured 15 months after end of treatment.
  
  
  CONCLUSIONS
  Sporotrichosis is presently occurring as an emerging zoonosis in Rio de Janeiro, and some unusual clinical forms have been diagnosed in humans. The cases reported here suggest atraumatic exposure to cats infected by S. schenckii.
authors.affiliation: Serviço de Zoonoses, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil. armando@ipec.fiocruz.br
authors.forename: Armando
authors.initials: A
authors.lastname: Schubach
authors.forename: Mônica Bastos
authors.initials: MB
authors.lastname: de Lima Barros
authors.forename: Tânia Maria Pacheco
authors.initials: TM
authors.lastname: Schubach
authors.forename: Antônio Carlos
authors.initials: AC
authors.lastname: Francesconi-do-Valle
authors.forename: Maria Clara
authors.initials: MC
authors.lastname: Gutierrez-Galhardo
authors.forename: Márcio
authors.initials: M
authors.lastname: Sued
authors.forename: Mariza
authors.initials: M
authors.lastname: de Matos Salgueiro
authors.forename: Paulo Cezar
authors.initials: PC
authors.lastname: Fialho-Monteiro
authors.forename: Rosani Santos
authors.initials: RS
authors.lastname: Reis
authors.forename: Keyla Belizia Feldman
authors.initials: KB
authors.lastname: Marzochi
authors.forename: Bodo
authors.initials: B
authors.lastname: Wanke
authors.forename: Fátima
authors.initials: F
authors.lastname: Conceição-Silva
mesh_terms: D000328:Adult; D000818:Animals; D000935:Antifungal Agents / Q000627:therapeutic use*; D001938:Brazil / Q000453:epidemiology; D002371:Cat Diseases; D002415:Cats; D003229:Conjunctival Diseases / Q000188:drug therapy* / Q000473:pathology; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use*; D008875:Middle Aged; D013174:Sporotrichosis / Q000188:drug therapy* / Q000453:epidemiology / Q000473:pathology; D015047:Zoonoses / Q000453:epidemiology
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole