Gastric adenocarcinoma with leptomeningeal carcinomatosis as the presenting manifestation: an autopsy case report.
Leptomeningeal carcinomatosis is a clinically important and severe complication in patients with cancer. Leptomeningeal involvement as a secondary event in gastric carcinoma is rarely reported and usually occurs late in advanced disease. Herein, we report a case of leptomeningeal carcinomatosis as the initial manifestation of a previously asymptomatic gastric adenocarcinoma. The clinical features and the appropriate diagnostic procedures are discussed.
Braeuninger
Stefan
S
Institute of Neuropathology, Department of Gastroenterology, Otto-von-Guericke-University, Magdeburg, Germany. s.braeuninger@gmx.net
Mawrin
Christian
C
Malfertheiner
Peter
P
Schildhaus
Hans-Ulrich
HU
Seiler
Christiane
C
Dietzmann
Knut
K
Lins
Hartmut
H
D000230:Adenocarcinoma / Q000473:pathology / Q000556:secondary*; D000368:Aged; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology / Q000556:secondary*; D009382:Neoplasms, Unknown Primary / Q000473:pathology*; D013274:Stomach Neoplasms / Q000473:pathology*