title: Human blood group genes 2004: chromosomal locations and cloning strategies.
abstract: Of the 29 human blood group system genes, 27 have been localized to 14 autosomes and 2 have been assigned to the X chromosome. It is remarkable that 28 of the 29 system genes have now been localized to a single cytogenetic band on a specific chromosome. In this review, we summarize the chromosomal locations and cloning strategies used for those genes encoding blood group systems. We highlight such information about the 3 most recently defined blood group systems (I, GLOB, and GIL). In addition, we provide new information about 2 older blood group systems (SC and RAPH) whose polymorphisms have been defined in cloned genes.
authors.affiliation: Transfusion Medicine Program, Depatment of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA.
authors.forename: Lennart
authors.initials: L
authors.lastname: Lögdberg
authors.forename: Marion E
authors.initials: ME
authors.lastname: Reid
authors.forename: Ryan E
authors.initials: RE
authors.lastname: Lamont
authors.forename: Teresa
authors.initials: T
authors.lastname: Zelinski
mesh_terms: D001789:Blood Group Antigens / Q000235:genetics*; D002874:Chromosome Mapping / Q000379:methods*; D041321:Chromosomes, Human, X; D003001:Cloning, Molecular; D003582:Cytogenetics / Q000379:methods; D004912:Erythrocytes / Q000378:metabolism; D005821:Genetic Techniques; D006801:Humans; D011110:Polymorphism, Genetic
chemical_list: D001789:Blood Group Antigens