Perinuclear translocation of hsp 27 in shear stress exposed human endothelial cells.
Expression of hsp 27 in human umbilical vein endothelial cells exposed to a shear stress was investigated. Using immunostaining, it was concluded that shear stress results in perinuclear translocation of hsp 27. Polymerization of actin microfilaments plays an important role in this process.
Yoo
So Young
SY
Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 305-701, Korea. yoosy@kaist.ac.kr
Chung
Chanil
C
Kim
Jung Kyung
JK
Chang
Jun Keun
JK
D008841:Actin Cytoskeleton / Q000378:metabolism; D000199:Actins / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism*; D002478:Cells, Cultured; D042783:Endothelial Cells / Q000378:metabolism; D004730:Endothelium, Vascular / Q000166:cytology / Q000378:metabolism*; D018840:HSP70 Heat-Shock Proteins / Q000378:metabolism*; D006801:Humans; D021381:Protein Transport; D013314:Stress, Mechanical; D014471:Umbilical Veins / Q000166:cytology
D000199:Actins; D018840:HSP70 Heat-Shock Proteins