title: Morphological studies in modern teratological investigations.
abstract: Despite the variety of modern molecular techniques available, examination of foetal anatomy is still a fundamental part of teratological studies in evaluating the developmental toxicity of xenobiotics or other non-chemical factors. The article presents contemporary methods of embryotoxicity and foetotoxicity assessment. A single alizarin red S and double alcian blue followed by alizarin red S staining, as well as various methods of soft tissue examination are discussed.
authors.affiliation: Experimental Teratology Unit, Department of Human Anatomy, Medical University of Lublin, 20-074 Lublin, Poland. fb3@wp.pl
authors.forename: Franciszek
authors.initials: F
authors.lastname: Burdan
authors.forename: Justyna
authors.initials: J
authors.lastname: Szumiło
authors.forename: Jarosław
authors.initials: J
authors.lastname: Dudka
authors.forename: Robert
authors.initials: R
authors.lastname: Klepacz
authors.forename: Magdalena
authors.initials: M
authors.lastname: Błaszczak
authors.forename: Michał
authors.initials: M
authors.lastname: Solecki
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Korobowicz
authors.forename: Anna
authors.initials: A
authors.lastname: Chałas
authors.forename: Janusz
authors.initials: J
authors.lastname: Klepacki
authors.forename: Michał
authors.initials: M
authors.lastname: Palczak
authors.forename: Agata
authors.initials: A
authors.lastname: Zuchnik-Wrona
authors.forename: Anna
authors.initials: A
authors.lastname: Hadała-Kiś
authors.forename: Zygmunt
authors.initials: Z
authors.lastname: Urbanowicz
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Wójtowicz
mesh_terms: D000423:Alcian Blue / Q000737:chemistry; D000818:Animals; D000880:Anthraquinones / Q000737:chemistry; D001842:Bone and Bones / Q000033:anatomy & histology / Q000737:chemistry; D004396:Coloring Agents / Q000737:chemistry; D005260:Female; D005333:Fetus / Q000033:anatomy & histology* / Q000187:drug effects; D006801:Humans; D018811:Maternal Exposure; D051381:Rats; D018600:Teratology / Q000379:methods; D015262:Xenobiotics / Q000494:pharmacology
chemical_list: D000880:Anthraquinones; D004396:Coloring Agents; D015262:Xenobiotics; C004468:Alizarin Red S; D000423:Alcian Blue