title: Impact of ovarian endometrioma on oocytes and pregnancy outcome in in vitro fertilization.
abstract: OBJECTIVE
  To evaluate the effect of endometriosis and the presence of an ovarian endometrioma on outcomes of conventional in vitro fertilization (IVF).
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  Reproductive Unit, Department of Obstetrics and Gynecology, Tokai University Hospital.
  
  
  METHODS
  Group A: 80 cycles with ovarian endometriomas; group B: 248 cycles with endometriosis but without endometrial cysts at the time of oocyte retrieval; group C: 283 cycles undergoing IVF because of tubal factor without endometriosis.
  
  
  METHODS
  All conventional in vitro fertilization-embryo transfer (IVF-ET) with previous diagnostic laparoscopy. An endometrioma was diagnosed by direct aspiration at the time of oocyte retrieval.
  
  
  METHODS
  Retrieved number of oocytes, fertilization rate, embryo quality, implantation rate, pregnancy rate, and live birth rate for all cases. In group A, the number of retrieved oocytes in relation to the volume of the endometrioma and affected laterality.
  
  
  RESULTS
  Fewer oocytes were retrieved from groups A and B than from group C (P<.005). The number of retrieved oocytes was not dependent on the volume of endometrial cyst(s). Fertilization rates were similar among the groups. Group A had slightly but not significantly higher rates of morphologically good-quality embryos (group A: 67.2%, group B: 63.0%, group C: 58.1%), implantation (group A: 14.1%, group B: 11.7%, group C: 11.3%), and pregnancy (group A: 25.3%, group B: 22.3%, group C: 23.9%).
  
  
  CONCLUSIONS
  Endometriosis affects oocyte number but not embryo quality or pregnancy outcome, irrespective of the presence of an ovarian endometrioma.
authors.affiliation: Department of Obstetrics and Gynecology, Specialized Clinical Science, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa 259-1193, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Suzuki
authors.forename: Shun-ichiro
authors.initials: S
authors.lastname: Izumi
authors.forename: Hidehiko
authors.initials: H
authors.lastname: Matsubayashi
authors.forename: Hideo
authors.initials: H
authors.lastname: Awaji
authors.forename: Kikuo
authors.initials: K
authors.lastname: Yoshikata
authors.forename: Tsunehisa
authors.initials: T
authors.lastname: Makino
mesh_terms: D000328:Adult; D004715:Endometriosis / Q000150:complications* / Q000473:pathology; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000150:complications* / Q000628:therapy*; D010535:Laparoscopy; D009865:Oocytes / Q000166:cytology*; D010062:Ovulation Induction; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies