title: An old target revisited: two new privileged skeletons and an unexpected binding mode for HIV-protease inhibitors.
authors.affiliation: Institut für Pharmazeutische Chemie, Philipps-Universität Marburg, Marbacher Weg 6, 35032 Marburg, Germany.
authors.forename: Edgar
authors.initials: E
authors.lastname: Specker
authors.forename: Jark
authors.initials: J
authors.lastname: Böttcher
authors.forename: Hauke
authors.initials: H
authors.lastname: Lilie
authors.forename: Andreas
authors.initials: A
authors.lastname: Heine
authors.forename: Andreas
authors.initials: A
authors.lastname: Schoop
authors.forename: Gerhard
authors.initials: G
authors.lastname: Müller
authors.forename: Nils
authors.initials: N
authors.lastname: Griebenow
authors.forename: Gerhard
authors.initials: G
authors.lastname: Klebe
mesh_terms: D001665:Binding Sites; D015195:Drug Design; D004353:Drug Evaluation, Preclinical; D017320:HIV Protease Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry*; D006801:Humans; D006860:Hydrogen Bonding; D008958:Models, Molecular; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D013450:Sulfones / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D017320:HIV Protease Inhibitors; D013450:Sulfones