The onset and extinction of neural spiking: a numerical bifurcation approach.
We study the onset of neural spiking when the equilibrium rest state loses stability by the change of a critical parameter, the applied current. In the case of the well-known Morris-Lecar model, we start from a complete numerical study of the bifurcation diagram in the most relevant two-parameter range. This diagram includes all equilibrium and limit cycle bifurcations, thus correcting and completing earlier studies. We discuss and classify the behavior of the spiking orbits, when increasing or decreasing the applied current. A complete classification can be extracted from the complete bifurcation diagram. It is based on three components: bifurcation type of the equilibrium at the loss of stability, subcritical behavior in the limit of decreasing the applied current and supercritical behavior in the limit of increasing the applied current.
Govaerts
W
W
Department of Applied Mathematics and Computer Science, Ghent University, Krijgslaan 281-S9, B-9000 Ghent, Belgium. willy.govaerts@ugent.be
Sautois
B
B
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D008433:Mathematics; D008959:Models, Neurological; D009415:Nerve Net; D009474:Neurons / Q000145:classification / Q000502:physiology*; D017711:Nonlinear Dynamics; D013997:Time Factors