title: [Measurements of respiratory motion using fast magnetic resonance imaging and inductively-coupled marker coils].
abstract: The respiratory motion of the thoracic wall provides indirect information about the breathing displacement of the inner organs. To analyze the correlation between thoracic wall and lung motion for applications in radiation therapy, the breathing displacement of the lung is visualized with a fast gradient echo pulse sequence (trueFISP) at a rate of 2-3 images/sec. For quantification of the motion, a small inductively-coupled marker coil is attached to the chest wall and detected with a fast projection technique. Since the marker coil generates a flip angle amplification (factor 15) in its interior, very small nominal flip angles of 2 degrees can be used during the projection measurements which do not affect the image quality of the trueFISP images. Volunteer studies with the marker coil showed a good agreement with simultaneously acquired breathing belt data and position information extracted from the MR images. Whereas the breathing belt provided reliable data only within a certain dynamic range, the marker coil could detect also extreme breathing excursions with a precision better than 2 millimeters.
authors.affiliation: Deutsches Krebsforschungszentrum, Forschungsschwerpunkt Innovative Krebsdiagnostik und Therapie, Heidelberg.
authors.forename: Hendrik
authors.initials: H
authors.lastname: Zimmermann
authors.forename: Reiner
authors.initials: R
authors.lastname: Umathum
authors.forename: Christian
authors.initials: C
authors.lastname: Plathow
authors.forename: Wolfhard
authors.initials: W
authors.lastname: Semmler
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Nitz
authors.forename: Michael
authors.initials: M
authors.lastname: Bock
mesh_terms: D004867:Equipment Design; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D012132:Respiratory Muscles / Q000473:pathology / Q000502:physiology; D012143:Respiratory Physiological Phenomena; D012680:Sensitivity and Specificity