Multifocal sporotrichosis with meningeal involvement in a patient with AIDS.
This report describes a 29-year-old man with AIDS and disseminated lymphocutaneous sporotrichosis diagnosis presenting a poor therapeutic adhesion to itraconazole therapy that later evolved to neurological impairment and death. Necropsy showed granulomatous reaction and yeast-like forms similar to Sporothrix schenckii in meninges, lymph nodes, marrow bone, skin, testicles, epididymides and pancreas. Meningeal sporotrichosis cases associated to AIDS are reviewed in brief.
Silva-Vergara
Mario León
ML
Departamento de Clínica Médica, Disciplina de Doenças Infecciosas e Parasitárias e, Faculdade de Medicina do Triângulo Mineiro, Uberaba, Brazil. dip_fmtm@mednet.com.br
Maneira
Frederico Ricardo Zago
FR
De Oliveira
Renata Mônica
RM
Santos
Celso Tadeu Barbosa
CT
Etchebehere
Renata Margarida
RM
Adad
Sheila Jorge
SJ
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001938:Brazil; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D016921:Meningitis, Fungal / Q000150:complications* / Q000382:microbiology / Q000473:pathology; D013175:Sporothrix / Q000187:drug effects / Q000302:isolation & purification; D013174:Sporotrichosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
D000935:Antifungal Agents; D017964:Itraconazole