Hypercalcemia in hepatic tuberculosis: a case report in Korea.
Although primary hyperparathyroidism and malignant diseases account for approximately 90% of the causes of hypercalcemia, they could occur in association with granulomatous diseases such as tuberculosis or sarcoidosis, especially in developing countries. Hepatic tuberculosis is difficult to diagnosis without suspicion in cases with normal findings on chest radiographs. We report a 70-year-old woman who presented with hypercalcemia due to hepatic tuberculosis. The diagnosis was made by a computed tomography scan and laparoscopic evaluation. After treatment with anti-tuberculosis medication, her hypercalcemia resolved. Increased vitamin D synthesis by activated macrophages in the granuloma tissue is the major mechanism of hypercalcemia in tuberculosis.
Kang
Eun Seok
ES
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.
Do
Mi Young
MY
Park
So Young
SY
Hur
Kyu Yeon
KY
Ahn
Chul Woo
CW
Cha
Bong Soo
BS
Lim
Sung Kil
SK
Kim
Kyung Rae
KR
Lee
Hyun Chul
HC
D000368:Aged; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000150:complications*; D007723:Korea; D014057:Tomography, X-Ray Computed; D014386:Tuberculosis, Hepatic / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy