title: Symmetric bony involvement of the lower extremities with lymphoma demonstrated on gallium scintigraphy.
abstract: Primary or secondary lymphoma of the bone is uncommon. The sites of bony involvement include, in decreasing order of frequency, the spine, long bones, pelvis, ribs, and skull. A 66-year-old man with an atypical lineage of B-cell non-Hodgkin lymphoma is presented. The unusual initial presentation of the lymphoma included symmetric bony involvement of bilateral tibiae and the distal right femur, demonstrated on gallium-67 scintigraphy. The patient subsequently demonstrated resolution of the gallium-avid disease after treatment with fludarabine, cyclosporine, and ATG. This case also demonstrates the limitations of plain radiograph and the usefulness of MRI in the diagnosis of bony lymphoma.
authors.affiliation: Department of PET and Nuclear Medicine, Royal Prince Alfred Hospital, Camperdown, Australia.
authors.forename: Choong L
authors.initials: CL
authors.lastname: Wong
authors.forename: Robert
authors.initials: R
authors.lastname: Mansberg
authors.forename: Malia
authors.initials: M
authors.lastname: Yosufzai
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D002951:Citrates; D005708:Gallium; D006801:Humans; D035002:Lower Extremity / Q000000981:diagnostic imaging*; D016393:Lymphoma, B-Cell / Q000000981:diagnostic imaging*; D008297:Male; D019275:Radiopharmaceuticals; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods
chemical_list: D002951:Citrates; D019275:Radiopharmaceuticals; D005708:Gallium; C103850:gallium citrate