title: Resting and stimulated whole salivary flow rates in Sjögren's syndrome patients over time: a diagnostic aid for subsidized dental care?
abstract: The aim of the present study was to evaluate Swedish and Norwegian criteria currently applied in the assessment of eligibility for subsidized dental care of Sjogren's syndrome (SS) patients. These criteria are partly based on a single salivary test showing a resting whole salivary secretion rate of < or =0.1 mL/min. Thirty secondary Sjogren (SSS) patients (29 F and 1 M) participated for the duration of the study, in which resting (RWS) and stimulated (SWS) whole salivary flow rates were collected in the morning and afternoon, over 3 consecutive weeks, once per week, as well as at different times over a 5-year period. Twenty patients presented levels of RWS flow rates of < or =0.1 mL/min on one or more occasions over a 3-week period, while 8 of these also exceeded, on one or more occasions, the cut-off level of 0.1 mL/min, indicating that salivary flow rates varied over time. Six patients showed consistently low secretion rates of RWS as well as of SWS, estimated as < or =0.1 mL/min and <0.7 mL/min, respectively. Based on the results, salivary tests that are to be used as a diagnostic aid for SS diagnosis, and thus as a basis for inclusion within the subsidy net for dental care, must be taken on several occasions in order to more accurately give information about salivary gland function. In line with this, current regulations governing the eligibility of SS patients within subsidized dental care programs should be reviewed.
authors.affiliation: Section of Dental Pharmacology and Pharmacotherapy, University of Oslo, Norway.
authors.forename: Lars
authors.initials: L
authors.lastname: Jorkjend
authors.forename: Anders
authors.initials: A
authors.lastname: Johansson
authors.forename: Ann-Katrin
authors.initials: AK
authors.lastname: Johansson
authors.forename: Axel
authors.initials: A
authors.lastname: Bergenholtz
mesh_terms: D000328:Adult; D000368:Aged; D004608:Eligibility Determination / Q000379:methods; D005260:Female; D006801:Humans; D007347:Insurance, Dental; D008297:Male; D008875:Middle Aged; D009313:National Health Programs; D012463:Saliva / Q000378:metabolism*; D012636:Secretory Rate; D012859:Sjogren's Syndrome / Q000175:diagnosis*; D013548:Sweden