Cytomegalovirus infection and chronic graft-versus-host disease are significant predictors of renal failure after allogeneic hematopoietic stem cell transplantation.
We investigated the frequencies and predictive factors of prolonged renal failure (PRF) in a retrospective study of 181 consecutive patients undergoing allogeneic hematopoietic stem cell transplantation. Twenty-six patients (23% of long-term survivors) developed PRF. We identified 4 independent prognostic factors; cytomegalovirus infection and chronic graft-versus-host disease appeared as major risk factors for PRF.
Deconinck
Eric
E
Kribs
Marc
M
Rebibou
Jean-Michel
JM
Bulabois
C E
CE
Ducloux
Didier
D
Cahn
Jean-Yves
JY
D003586:Cytomegalovirus Infections / Q000150:complications*; D006086:Graft vs Host Disease / Q000150:complications*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D011237:Predictive Value of Tests; D051437:Renal Insufficiency / Q000209:etiology*; D012189:Retrospective Studies; D014184:Transplantation, Homologous