title: [Diagnosis and following-up and analysis of pathogenesis for congenital hearing loss].
abstract: OBJECTIVE
  To investigate the incidence and the relevant high-risk factors of congenital hearing loss for infants from well-baby nursery and newborn intensive care unit. To explore the scientific and feasible mode of early diagnosis, following-up and early intervention.
  
  
  METHODS
  Two-stage universal newborn hearing screening ( UNHS ) were performed by using transient otoacoustic emission ( TEOAE ). Auditory brainstem responses ( ABRs) and 40 Hz auditory event related potentials (40 Hz-AERPs) was used as diagnostic tests for those failed re-screening at three-month old. Two kinds of infants who had abnormal ABRs or high-risk factors of hearing loss received following-up and routine audiological evaluation from 6 months to 3 years of age. Each infant with congenital hearing loss received personalized intervention.
  
  
  RESULTS
  The incidence of congenital hearing loss among infants who received UNHS was 5.73 per thousand. The incidence of congenital hearing loss was 20.02 per thousand in NICU and 3.67 in WBN.
  
  
  CONCLUSIONS
  Whether passed the UNHS or not , infants from NICU should receive ABR and 40 HzAERP tests. The following-up population includes infants with abnormal ABRs or high-risk factors of hearing loss. Following-up and early intervention should be personalized.
authors.affiliation: linq5310@sina.com
authors.forename: Lu-xia
authors.initials: LX
authors.lastname: Gong
authors.forename: Yu-jun
authors.initials: YJ
authors.lastname: Liu
authors.forename: Wen-ying
authors.initials: WY
authors.lastname: Nie
authors.forename: Li-li
authors.initials: LL
authors.lastname: Xing
authors.forename: Ying-hui
authors.initials: YH
authors.lastname: Li
authors.forename: Hui
authors.initials: H
authors.lastname: Li
authors.forename: Yi-sheng
authors.initials: YS
authors.lastname: Qi
authors.forename: Chuanyu
authors.initials: C
authors.lastname: Liang
mesh_terms: D042241:Early Diagnosis; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D005500:Follow-Up Studies; D034381:Hearing Loss / Q000151:congenital / Q000175:diagnosis* / Q000209:etiology*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D015997:Neonatal Screening; D017084:Otoacoustic Emissions, Spontaneous