High frequency of Y chromosome microdeletions in idiopathic azoospermic men with high follicle-stimulating hormone levels.
Y chromosome microdeletions were detected in 33.3% (6 out of 18) of idiopathic azoospermic patients with high serum follicle-stimulating hormone (FSH) levels in the present study. The results suggest that it may be necessary to detect microdeletions in patients with azoospermia, especially for those with high serum FSH levels, before assisted reproductive technology (ART) is provided to them.
Wang
Li-Quan
LQ
Department of Reproductive Endocrinology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310 006, China.
Huang
He-Feng
HF
Jin
Fan
F
Qian
Yu-Li
YL
Cheng
Qi
Q
D000328:Adult; D041322:Chromosomes, Human, Y; D005640:Follicle Stimulating Hormone / Q000097:blood*; D017353:Gene Deletion; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009845:Oligospermia / Q000097:blood* / Q000235:genetics*; D013739:Testosterone / Q000097:blood
D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone