The structure of alpha-helical coiled coils.
alpha-Helical coiled coils are versatile protein domains, supporting a wide range of biological functions. Their fold is probably better understood than that of any other protein; indeed, uniquely among folds, their structure can be computed from a set of parametric equations. Here, we review the principles of coiled-coil structure, the determinants of their folding and stability, and the diversity of structural forms they assume.
Lupas
Andrei N
AN
Max-Planck-Institute for Developmental Biology, D-72076 Tübingen, Germany.
Gruber
Markus
M
D000818:Animals; D006801:Humans; D007536:Isomerism; D008958:Models, Molecular; D017510:Protein Folding; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry*
D011506:Proteins