title: [The effect of ampicillin on the electrophysical properties of Escherichia coli cells].
abstract: The study of the effect of ampicillin on the electrophysical properties of Escherichia coli cells showed that this antibiotic influences the orientational spectra (OS) of the ampicillin-susceptible E. coli strains K-12 and XL-1 within the frequency range 10-1000 kHz of the orienting electric field and does not affect the OS of the ampicillin-resistant strains K-12(pUC-18) and XL-1(pHEN1). The change in the electrooptical signal of the ampicillin-susceptible cells was maximum at an ampicillin concentration of 50 microg/ml and did not depend on the exposure time. The conclusion is drawn that changes in the OS of cells can be used to evaluate their resistance to ampicillin.
authors.forename: O I
authors.initials: OI
authors.lastname: Guliĭ
authors.forename: L N
authors.initials: LN
authors.lastname: Markina
authors.forename: O V
authors.initials: OV
authors.lastname: Ignatov
authors.forename: S Iu
authors.initials: SIu
authors.lastname: Shchegolev
authors.forename: I S
authors.initials: IS
authors.lastname: Zaĭtseva
authors.forename: V D
authors.initials: VD
authors.lastname: Bunin
authors.forename: V V
authors.initials: VV
authors.lastname: Ignatov
mesh_terms: D000667:Ampicillin / Q000494:pharmacology*; D000668:Ampicillin Resistance; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004574:Electromagnetic Fields; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects* / Q000502:physiology*; D013057:Spectrum Analysis
chemical_list: D000900:Anti-Bacterial Agents; D000667:Ampicillin