Effect of both elevated troponin-I and peripheral white blood cell count on prognosis in patients with suspected myocardial injury.
We found a high white blood cell count (>11,000/mul) to be of additive prognostic value to high troponin-I levels in predicting risk of recurrent nonfatal myocardial infarctions and all-cause mortality in patients who present with acute coronary syndromes and non-ST-elevation myocardial infarctions. A high troponin-I level or white blood cell count increased the odds ratio of an event to 2.2 (95% confidence interval 1.0 to 4.73, p = 0.05), but high values for the 2 markers increased the odds ratio to 4.5 (95% confidence interval 1.42 to 14.21, p = 0.01).
Zahid
Maliha
M
VA Pittsburgh Healthcare System, Center for Health Equity Research and Promotion, Pittsburgh, Pennsylvania, USA.
Sonel
Ali F
AF
Kelley
Mary E
ME
Wall
Lauren
L
Whittle
Jeff
J
Fine
Michael J
MJ
Good
Chester B
CB
D000368:Aged; D015415:Biomarkers / Q000097:blood*; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D009203:Myocardial Infarction / Q000150:complications* / Q000175:diagnosis*; D011237:Predictive Value of Tests; D011379:Prognosis; D012008:Recurrence; D012307:Risk Factors; D019210:Troponin I / Q000097:blood*
D015415:Biomarkers; D019210:Troponin I