Endotoxic shock after gamete intrafallopian transfer.
OBJECTIVE
To report an extremely rare case of endotoxic shock due to Enterobacter cloacae that occurred after laparoscopy for gamete intrafallopian transfer (GIFT) in a nulligravid woman.


METHODS
Private fertility center in Cape Town, South Africa.


METHODS
Case report.


METHODS
A 34-year-old woman with primary infertility.


METHODS
Routine preparation for GIFT procedure, sonar aspiration to obtain oocytes, followed by GIFT. Endotoxic shock developed within hours after the procedure, followed by admission to the intensive care unit, intravenous antibiotic therapy, mechanical ventilation, and abdominal hysterectomy.


METHODS
Preventing patient mortality and morbidity.


RESULTS
Discharge from the intensive care unit occurred on day 11 after GIFT, which was day 8 after surgery. A MEDLINE search (1980 to 2003) found no previous literature on endotoxic shock associated with assisted reproduction.


CONCLUSIONS
Gram-negative infection with subsequent endotoxic shock after assisted reproductive techniques is extremely rare. As this case report shows, early diagnosis and active management of these cases are mandatory to prevent serious complications and mortality.
Slabbert
Dawie R
DR
Department of Obstetrics and Gynecology, Stellenbosch University and Tygerberg Hospital, Tygerberg, South Africa.
Kruger
Thinus F
TF
Siebert
Thomas I
TI
Stead
Piers
P
D000328:Adult; D003428:Cross Infection / Q000209:etiology / Q000382:microbiology; D016972:Enterobacter cloacae / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000209:etiology* / Q000382:microbiology; D005260:Female; D015181:Gamete Intrafallopian Transfer / Q000009:adverse effects*; D006801:Humans; D007044:Hysterectomy / Q000379:methods; D007247:Infertility, Female / Q000628:therapy*; D010535:Laparoscopy / Q000009:adverse effects*; D011247:Pregnancy; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects; D012772:Shock, Septic / Q000209:etiology* / Q000382:microbiology; D016896:Treatment Outcome; D014591:Uterine Diseases / Q000209:etiology* / Q000382:microbiology / Q000601:surgery