title: [Acute splenic sequestration: a rare and severe complication of sickle cell anemia in adults. A case report].
abstract: BACKGROUND
  Acute splenic sequestration, a well-recognized complication of sickle cell syndromes, is characterized by a sudden decrease in haemoglobin concentration and marked painless splenomegaly. We report a case illustrating the outcome and the treatment options of this complication.
  
  
  METHODS
  A 45-year old homozygous woman developed acute splenic sequestration with severe anemia. Red blood cells transfusion led to transient improvement but a relapse-required splenectomy. Long-term outcome was favorable.
  
  
  CONCLUSIONS
  Acute splenic sequestration is a severe complication mainly observed in children. Despite the severity of this complication, prompt diagnosis and appropriate therapy, and particularly red blood cells transfusions, led to a complete recovery. Splenectomy is required in the more severe form of the disease.
authors.affiliation: Service de médecine interne 1, unité des maladies génétiques du globule rouge et d'Aphérèse 1, CHU Henri-Mondor, AP-HP, 51, avenue de Lattre-de-Tassigny, 94000 Créteil, France.
authors.forename: A
authors.initials: A
authors.lastname: Habibi
authors.forename: M
authors.initials: M
authors.lastname: Khellaf
authors.forename: D
authors.initials: D
authors.lastname: Bachir
authors.forename: A
authors.initials: A
authors.lastname: Schaeffer
authors.forename: F
authors.initials: F
authors.lastname: Galactéros
authors.forename: B
authors.initials: B
authors.lastname: Godeau
mesh_terms: D000208:Acute Disease; D000755:Anemia, Sickle Cell / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012720:Severity of Illness Index; D013158:Splenic Diseases / Q000209:etiology*