Novel approaches in GVHD therapy.
Severe graft-versus-host disease is a lethal complication to allogeneic haemopoietic stem cell transplantation. This short review gives an overview of novel treatment strategies. Psoralen-enhanced UVA irradiation (PUVA), extracorpoal PUVA, antibodies against IL-2 and TNF-alpha, thalidomide, octreotide, and mesenchymal stem cells are briefly discussed.
Svennilson
J
J
Centre for Allogeneic Stem Cell transplantation/Paediatric Haematology Unit, Huddinge University Hospital, Stockholm, Sweden. johan.svennilson@klinvet.ki.se
D006086:Graft vs Host Disease / Q000628:therapy*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D045164:Mesenchymal Stem Cell Transplantation; D011701:PUVA Therapy
D007166:Immunosuppressive Agents