Renal metastasis from papillary thyroid microcarcinoma.
Papillary or follicular microcarcinoma of the thyroid comprises 10-20% of all thyroid malignancies. Most of these diseases exhibit slow progression and have a favorable prognosis. Distant metastasis caused by thyroid microcarcinoma is uncommon, and is usually found in the lung or bone. Thyroid microcarcinoma with metastasis to the kidney has not previously been reported. Clinically detectable well-differentiated metastatic thyroid carcinoma to the kidney is rare, and only 16 cases have been reported. Herein we describe a case of metastatic papillary thyroid microcarcinoma to the kidney in a patient with a pelvic fracture and pulmonary metastasis. The patient underwent a total thyroidectomy, radiotherapy, ablation treatment with 131I and thyroxine suppressive therapy. In conclusion, microcarcinoma cannot be ignored. Although uncommon, metastases may arise.
Liou
Miaw-Jene
MJ
Section of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital and Chang Gung University, Linkou, Taiwan. lioumj@adm.cgmh.org.tw
Lin
Jen-Der
JD
Chung
Mei-Hsin
MH
Liau
Chi-Ting
CT
Hsueh
Chuen
C
D018263:Adenocarcinoma, Follicular / Q000175:diagnosis / Q000473:pathology / Q000556:secondary*; D000231:Adenocarcinoma, Papillary / Q000175:diagnosis / Q000473:pathology / Q000556:secondary*; D001859:Bone Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary; D002114:Calcinosis / Q000175:diagnosis / Q000473:pathology; D018450:Disease Progression; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary*; D008175:Lung Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary; D008875:Middle Aged; D010384:Pelvic Bones / Q000473:pathology; D013954:Thyroglobulin / Q000097:blood; D013961:Thyroid Gland / Q000473:pathology; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
D013954:Thyroglobulin