[Small bowel diaphragm disease associated with NSAIDs with histology of neuromuscular and vascular hamartoma. Case report and literature review].
Diaphragm disease (DD) induced by non-steroidal anti-inflammatory drugs (NSAIDs) and neuromuscular and vascular hamartoma (NMVH) are rare entities that can be difficult to recognize clinically, radiologically and pathologically. Both may cause small bowel obstruction and both reveal annular constrictions macroscopically. However, the 2 entities differ in that the constrictions are purely fibrous in DD whereas they have a hamartomatous histopathology in NMVH. We describe the case of a 76-year-old woman with a history of prolonged NSAID use who developed clinical features and gross pathology consistent with DD and histopathology of NMVH.
Company
M M
MM
Servicios de Anatomía Patológica, Radiología y Digestivo, Hospital Universitario Son Dureta, Palma de Mallorca, Islas Baleares, Spain. mcompany@hotmail.com
Usamentiaga
E
E
Torralba
J
J
Bonet
L
L
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D005260:Female; D006222:Hamartoma / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D007077:Ileal Diseases / Q000139:chemically induced* / Q000473:pathology; D007415:Intestinal Obstruction / Q000209:etiology*
D000894:Anti-Inflammatory Agents, Non-Steroidal