The Brugada ECG pattern in a neonate.
We report a neonate resuscitated from sudden death with a Brugada ECG pattern several days after the initial event. The baby was subsequently diagnosed with a fatty acid oxidation disorder (medium chain Acyl-CoA dehydrogenase deficiency or MCAD). We speculate that free fatty acid accumulation can give rise to the Brugada ECG pattern.
Sanatani
Shubhayan
S
Division of Cardiology, British Columbia Children's Hospital, Vancouver, Canada. ssanatani@cw.bc.ca
Mahkseed
Nawal
N
Vallance
Hilary
H
Brugada
Ramon
R
D044944:Acyl-CoA Dehydrogenases / Q000172:deficiency; D002037:Bundle-Branch Block / Q000175:diagnosis* / Q000503:physiopathology; D003937:Diagnosis, Differential; D004562:Electrocardiography; D006801:Humans; D007231:Infant, Newborn; D008052:Lipid Metabolism, Inborn Errors / Q000175:diagnosis* / Q000201:enzymology / Q000503:physiopathology; D008297:Male; D013398:Sudden Infant Death; D013577:Syndrome
D044944:Acyl-CoA Dehydrogenases