title: Brain arteriovenous malformations: measurement of nidal volume using a combination of static and dynamic magnetic resonance angiography techniques.
abstract: Arteriovenous malformations of the brain are complex vascular lesions that are an important cause of death and long-term disability. Currently, catheter angiography (CA) is the reference standard procedure for the diagnosis and follow-up of treated arteriovenous malformations (AVMs). This is an invasive procedure with potential risks. Magnetic resonance angiography (MRA) is commonly used in neurovascular imaging as a non-invasive alternative. Various MRA techniques have been used in the diagnosis and follow-up of AVMs but these have suffered from lack of temporal or spatial resolution. In this 60-patient study we describe the combination of two techniques: dynamic magnetic resonance digital subtraction angiography with a high temporal resolution, and a non-dynamic contrast-enhanced time-of-flight sequence with a high spatial resolution technique, in the assessment of AVM. The results showed an excellent correlation between MRA and CA measurement of both maximum linear dimension and AVM nidus volume.
authors.affiliation: Academic Radiology Section, Royal Hallamshire Hospital, University of Sheffield, Glossop Road, Sheffield, S10 2JF, UK. s.nagaraja@shef.ac.uk
authors.forename: S
authors.initials: S
authors.lastname: Nagaraja
authors.forename: D
authors.initials: D
authors.lastname: Capener
authors.forename: S C
authors.initials: SC
authors.lastname: Coley
authors.forename: K J
authors.initials: KJ
authors.lastname: Lee
authors.forename: I D
authors.initials: ID
authors.lastname: Wilkinson
authors.forename: A A
authors.initials: AA
authors.lastname: Kemeny
authors.forename: P D
authors.initials: PD
authors.lastname: Griffiths
mesh_terms: D000328:Adult; D015901:Angiography, Digital Subtraction; D003287:Contrast Media; D005260:Female; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis*; D018810:Magnetic Resonance Angiography / Q000379:methods* / Q000592:standards; D008297:Male; D016037:Single-Blind Method
chemical_list: D003287:Contrast Media