title: Mediation of the relationship between inner voice experiences and health-related quality of life.
abstract: OBJECTIVE
  Appraisals tied to voice hearing and other subjective experiences pose serious challenges for nursing because of their implications for health and safety of voice hearers and others.
  
  
  METHODS
  An exploratory, correlational design involving hierarchical analysis of data from 337 voice hearers.
  
  
  RESULTS
  Inner voice experiences and subjective-deficit symptoms each had significant negative, independent effects on perceptions of the integrity of the functional nervous system, self-esteem, and health-related quality of life. The combination of subjective-deficit symptoms, perceptions of the integrity of the functional nervous system and self-esteem significantly reduced the negative impact of inner voice experiences on health related quality of life (R2 = .511). Perceived integrity of the functional nervous system and self-esteem together almost completely attenuated the impact of voice hearing on subjects' health-related quality of life.
  
  
  CONCLUSIONS
  These results highlight the need to develop strategies that can help voice hearers respond to inner experiences in a more positive manner.
authors.affiliation: University of Windsor, Faculty of Nursing, 303 Health Education Centre, P.O. Box 33830, Detroit, MI 49232, USA. mengland@uwindsor.ca
authors.forename: Margaret
authors.initials: M
authors.lastname: England
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D001294:Attitude to Health; D002648:Child; D002649:Child Abuse / Q000523:psychology; D019548:Crime Victims / Q000523:psychology; D005260:Female; D006212:Hallucinations / Q000150:complications / Q000451:nursing / Q000503:physiopathology / Q000523:psychology*; D006301:Health Services Needs and Demand; D006304:Health Status; D006801:Humans; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D009341:Negativism; D009420:Nervous System / Q000503:physiopathology; D024802:Nurse's Role; D015404:Nursing Methodology Research; D011568:Psychiatric Nursing / Q000458:organization & administration; D011788:Quality of Life / Q000523:psychology*; D012044:Regression Analysis; D012559:Schizophrenia / Q000150:complications / Q000175:diagnosis / Q000451:nursing / Q000503:physiopathology; D012565:Schizophrenic Psychology; D012649:Self Concept; D019966:Substance-Related Disorders / Q000150:complications / Q000523:psychology; D011795:Surveys and Questionnaires