Brain imaging and its implications for studying centrally targeted treatments in irritable bowel syndrome: a primer for gastroenterologists.
Research into brain-gut interactions, and the use of brain imaging, as potential investigative tools for functional gastrointestinal disorders, such as irritable bowel syndrome, is a promising new area. Studies are beginning to identify the structure and function of regions of the brain and their relationships to pain perception, stress, and other psychosocial variables. These imaging modalities may also have diagnostic potential, and perhaps even therapeutic applications, particularly with regard to understanding the benefit of centrally targeted modalities such as antidepressants and psychological treatments.
Drossman
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UNC Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Room 1110 Bioinformatics Building CB#7080, Chapel Hill, NC 27599-7080, USA. Douglas_drossman@med.unc.edu
D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D010146:Pain / Q000503:physiopathology; D049268:Positron-Emission Tomography; D011603:Psychophysiology; D013315:Stress, Psychological / Q000150:complications