title: Unusual metastatic spread of follicular thyroid carcinoma: report of a case.
abstract: Concurrent skull and liver metastases from follicular thyroid carcinoma is a very rare event. We herein present the case of a 72-year-old woman who initially presented with a swelling in the right supraorbital region that proved to be metastasis from a well-differentiated follicular thyroid carcinoma of clear-cell type. The metastatic workup disclosed a huge liver metastasis and an additional metastasis in the left iliac fossa. The treatment of this patient included a total thyroidectomy, an excision of the skull lesion, and the administration of radioiodine therapy, as well as thyroid-stimulating hormone (TSH) suppression therapy. However, the course of her disease was relentless. Although well-differentiated thyroid carcinoma tends to show an excellent course, the presence of metastatic disease leads to a very dismal prognosis.
authors.affiliation: First Department of Surgical Oncology, Saint Savvas Anticancer Institute, 171 Alexandra's Ave., 155 22, Athens, Greece.
authors.forename: Nickos G
authors.initials: NG
authors.lastname: Kelessis
authors.forename: Evangelos P
authors.initials: EP
authors.lastname: Prassas
authors.forename: Prassas P
authors.initials: PP
authors.lastname: Evangelos
authors.forename: Dimitra V
authors.initials: DV
authors.lastname: Dascalopoulou
authors.forename: Dascalopoulou V
authors.initials: DV
authors.lastname: Dimitra
authors.forename: Nikiforos A
authors.initials: NA
authors.lastname: Apostolikas
authors.forename: Apostolikas A
authors.initials: AA
authors.lastname: Nikiforos
authors.forename: Angeliki P
authors.initials: AP
authors.lastname: Tavernaraki
authors.forename: Tavernaraki P
authors.initials: TP
authors.lastname: Angeliki
authors.forename: Pericles P
authors.initials: PP
authors.lastname: Vassilopoulos P
authors.forename: Vassilopoulos P
authors.initials: VP
authors.lastname: Pericles
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000556:secondary* / Q000628:therapy; D000368:Aged; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy; D012888:Skull Neoplasms / Q000556:secondary* / Q000628:therapy; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000628:therapy; D013965:Thyroidectomy