title: EBER expression of pure urinary bladder lymphoepithelioma-like carcinoma in two unique Asian patients.
abstract: We describe the 2 unique Asian cases of pure urinary bladder lymphoepithelioma-like carcinoma (LELCA). One patient had metastatic pelvic lymphoadenopathy and the other with superficial tumor. The EBER in situ hybridization both showed negative results despite racial or geographical factors might influence the peculiar susceptibility of individuals of Asian ancestry to Epstein-Barr virus-associated lymphoepithelioma-like carcinoma. The 2 patients were treated pertinently with satisfactory outcomes and intravesical BCG instillation is performed to prevent superficial LELCA recurrence rationally.
authors.affiliation: Department of Urology, Taipei Medical University Hospital, Taipei, Taiwan.
authors.forename: Kuan-Chou
authors.initials: KC
authors.lastname: Chen
authors.forename: Han-Sun
authors.initials: HS
authors.lastname: Chiang
authors.forename: Chia-Lang
authors.initials: CL
authors.lastname: Fang
mesh_terms: D000368:Aged; D044466:Asian People; D014408:Biomarkers, Tumor / Q000235:genetics / Q000378:metabolism; D002294:Carcinoma, Squamous Cell / Q000208:ethnology / Q000378:metabolism* / Q000473:pathology; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D015870:Gene Expression; D006801:Humans; D017403:In Situ Hybridization; D008297:Male; D008875:Middle Aged; D012333:RNA, Messenger / Q000235:genetics; D016601:RNA-Binding Proteins / Q000235:genetics*; D012269:Ribosomal Proteins / Q000235:genetics*; D001749:Urinary Bladder Neoplasms / Q000208:ethnology / Q000378:metabolism* / Q000473:pathology
chemical_list: D014408:Biomarkers, Tumor; D012333:RNA, Messenger; D016601:RNA-Binding Proteins; D012269:Ribosomal Proteins; C067169:RPL22 protein, human