Comments on "accuracy limitations of chronaxie values".
Some additions/corrections are offered to Geddes, 2004. Stimulation is initiated by the second spatial derivative of the voltage along the nerve (activating function) rather than current density. Chronaxie values change with distance from the electrode. Anodic stimulation can excite via anodic break excitation, or via virtual cathodes around the anode.
Testerman
Roy L
RL
Medtronic, Inc, Neurological Division, Minneapolis, MN 55421-1200, USA. roy.lee.testerman@medtronic.com
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D002462:Cell Membrane / Q000502:physiology*; D002907:Chronaxy / Q000502:physiology*; D003627:Data Interpretation, Statistical; D004056:Differential Threshold / Q000502:physiology; D017097:Electric Impedance; D004558:Electric Stimulation / Q000295:instrumentation* / Q000379:methods*; D004566:Electrodes; D004735:Energy Transfer / Q000502:physiology*; D006801:Humans; D008564:Membrane Potentials / Q000502:physiology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity