title: An efficient synthesis of valienamine via ring-closing metathesis.
abstract: An efficient synthesis of valienamine is described. Valienamine was synthesized starting from commercially available 2,3,4,6-tetra-O-benzyl-D-glucose in nine steps, using ring-closing metathesis of (4S,5S,6S)-4,5,6-tribenzyloxy-7-(benzyloxymethyl)octa-1,7-dien-3-ol as a key step.
authors.affiliation: Center for Bioactive Molecular Hybrids and Department of Chemistry, Yonsei University, Seoul 120-749, Korea.
authors.forename: Young-Kil
authors.initials: YK
authors.lastname: Chang
authors.forename: Bo-Young
authors.initials: BY
authors.lastname: Lee
authors.forename: Dong Jun
authors.initials: DJ
authors.lastname: Kim
authors.forename: Gwan Sun
authors.initials: GS
authors.lastname: Lee
authors.forename: Heung Bae
authors.initials: HB
authors.lastname: Jeon
authors.forename: Kwan Soo
authors.initials: KS
authors.lastname: Kim
mesh_terms: D003500:Cyclization; D053138:Cyclohexenes; D006595:Hexosamines / Q000032:analysis / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D053138:Cyclohexenes; D006595:Hexosamines; C030791:valienamine