title: Endocrine disrupter--estradiol--in Chesapeake Bay tributaries.
abstract: Exogenous chemicals that interfere with natural hormonal functions are considered endocrine disrupting chemicals (EDCs). Estradiol (17beta-estradiol or E2) is the most potent of all xenoestrogens. Induction of vitellogenin (VTG) production in male fish occurs at E2 concentrations as low as 1 ng l-1. E2 reaches aquatic systems mainly through sewage and animal waste disposal. Surface water samples from ponds, rivers (Wicomico, Manokin and Pocomoke), sewage treatment plants (STPs), and coastal bays (Assawoman, Monie, Chincoteague, and Tangier Sound-Chesapeake Bay) on the Eastern Shore of Maryland were analyzed for E2 using enzyme linked immuno-sorbent assay (ELISA). E2 concentrations in river waters varied between 1.9 and 6.0 ng l-1. Highest E2 concentrations in river waters were observed immediately downstream of STPs. E2 concentrations in all the coastal bays tested were 2.3-3.2 ng l-1.
authors.affiliation: University of Maryland Eastern Shore, Princess Anne, MD 21853, USA.
authors.forename: Nelum
authors.initials: N
authors.lastname: Dorabawila
authors.forename: Gian
authors.initials: G
authors.lastname: Gupta
mesh_terms: D000818:Animals; D004703:Endocrine System / Q000187:drug effects; D004784:Environmental Monitoring; D004797:Enzyme-Linked Immunosorbent Assay; D004958:Estradiol / Q000032:analysis*; D005399:Fishes; D008297:Male; D008396:Maryland; D045483:Rivers; D012722:Sewage / Q000737:chemistry; D014818:Vitellogenesis; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D012722:Sewage; D014874:Water Pollutants, Chemical; D004958:Estradiol