title: Mechanical signalling: lessons from the past that control the future.
abstract: Relative movement between an implanted material and tissues can play a decisive role in generating the host response. As with other components of the biocompatibility of devices, it is essential to control the mechanical signalling associated with this movement if we are to optimise this response.
authors.affiliation: Clinical Engineering Department, Royal Liverpool University Hospital, UK. dfw.ce@liverpool.ac.uk
authors.forename: David
authors.initials: D
authors.lastname: Williams
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000009:adverse effects*; D005547:Foreign Bodies / Q000209:etiology* / Q000503:physiopathology*; D006801:Humans; D040542:Mechanotransduction, Cellular; D009068:Movement; D019736:Prostheses and Implants / Q000009:adverse effects*; D013314:Stress, Mechanical
chemical_list: D001672:Biocompatible Materials