The paradox of normal serum albumin in anorexia nervosa: a case report.
OBJECTIVE
Anorexia nervosa (AN) is associated with marked decreases in caloric intake and a corresponding reduction in body weight due to abnormal self body image. Although counterintuitive, hypoalbuminemia and vitamin deficiencies are not expected consequences of this disorder. Etiologic considerations for hypoalbuminemia are discussed.


METHODS
The case report of a patient with AN and marked hypoalbuminemia is presented and a focused literature review is reported.


RESULTS
Hypoalbuminemia was initially attributed to starvation. However, occult infection was ultimately responsible. Serum albumin concentration normalized with antibiotic therapy despite minimal restoration of body weight.


CONCLUSIONS
Hypoalbuminemia should not be considered a characteristic feature of AN even in the setting of progressive weight loss. The presence of other potentially life-threatening conditions should be sought, as reduced serum albumin concentration is a marker of inflammation in AN.
Krantz
Mori J
MJ
Department of Internal Medicine, Denver Health Medical Center, Denver, Colorado, USA.
Lee
David
D
Donahoo
William T
WT
Mehler
Philip S
PS
D000856:Anorexia Nervosa / Q000097:blood* / Q000150:complications; D005260:Female; D006801:Humans; D034141:Hypoalbuminemia / Q000209:etiology*; D007239:Infections / Q000150:complications / Q000175:diagnosis*; D008875:Middle Aged