title: Tc-99m labelled anti CD 66 antigranulocyte antibody imaging for assessment of bone marrow reserve.
abstract: Patients with metastatic disease to the bone marrow are at risk of significant hematologic toxicity, if they undergo myelotoxic chemotherapy. Tc-99m labelled Anti CD 66 monoclonal antibody imaging is a useful, noninvasive approach to the assessment of bone marrow reserve under such circumstances.
authors.affiliation: Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany. alexander.matthies@ukb.uni-bonn.de
authors.forename: Alexander
authors.initials: A
authors.lastname: Matthies
authors.forename: M
authors.initials: M
authors.lastname: Reinhardt
authors.forename: H
authors.initials: H
authors.lastname: Palmedo
authors.forename: S
authors.initials: S
authors.lastname: Ezziddin
authors.forename: B
authors.initials: B
authors.lastname: Abramowski
authors.forename: W
authors.initials: W
authors.lastname: Kuhn
authors.forename: H J
authors.initials: HJ
authors.lastname: Biersack
authors.forename: D
authors.initials: D
authors.lastname: von Mallek
mesh_terms: D000911:Antibodies, Monoclonal; D015703:Antigens, CD / Q000276:immunology; D000943:Antigens, Differentiation / Q000276:immunology; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D001853:Bone Marrow / Q000000981:diagnostic imaging* / Q000502:physiology*; D019046:Bone Marrow Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000556:secondary*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D002277:Carcinoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000556:secondary*; D015815:Cell Adhesion Molecules; D017024:Chemotherapy, Adjuvant; D005260:Female; D006098:Granulocytes / Q000276:immunology*; D006801:Humans; D008875:Middle Aged; D011237:Predictive Value of Tests; D016719:Radioimmunodetection / Q000379:methods; D012307:Risk Factors; D013667:Technetium
chemical_list: D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D000943:Antigens, Differentiation; D000970:Antineoplastic Agents; C069847:CD66 antigens; D015815:Cell Adhesion Molecules; D013667:Technetium