Pregnant "DES daughters" and their offspring.
OBJECTIVE
I am a 34-year-old woman in my second trimester of pregnancy. My mother took diethylstilbestrol when she was pregnant with me. Could my expected child be affected by this?


CONCLUSIONS
Animal studies suggest the child could be affected, but little data on humans strongly support this. You could plan to have your child monitored for a potential, though unlikely, effect.
Schechter
Tal
T
Finkelstein
Yaron
Y
Koren
Gideon
G
D000328:Adult; D004054:Diethylstilbestrol / Q000009:adverse effects*; D004968:Estrogens, Non-Steroidal / Q000009:adverse effects*; D005260:Female; D005833:Genital Neoplasms, Female / Q000139:chemically induced*; D006801:Humans; D018811:Maternal Exposure / Q000009:adverse effects*; D011247:Pregnancy; D012306:Risk; D014564:Urogenital Abnormalities / Q000139:chemically induced*
D004968:Estrogens, Non-Steroidal; D004054:Diethylstilbestrol