title: 3,3-Bisaryloxindoles as mineralocorticoid receptor antagonists.
abstract: Syntheses and SAR studies of 3,3-bisaryloxindole analogues provided potent mineralocorticoid receptor (MR) antagonists that were selective over other steroid nuclear hormone receptors.
authors.affiliation: Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA. neel_david_a@lilly.com
authors.forename: David A
authors.initials: DA
authors.lastname: Neel
authors.forename: Matthew L
authors.initials: ML
authors.lastname: Brown
authors.forename: Peter A
authors.initials: PA
authors.lastname: Lander
authors.forename: Timothy A
authors.initials: TA
authors.lastname: Grese
authors.forename: Jean M
authors.initials: JM
authors.lastname: Defauw
authors.forename: Robert A
authors.initials: RA
authors.lastname: Doti
authors.forename: Todd
authors.initials: T
authors.lastname: Fields
authors.forename: Sally Ann
authors.initials: SA
authors.lastname: Kelley
authors.forename: Stephon
authors.initials: S
authors.lastname: Smith
authors.forename: Karen M
authors.initials: KM
authors.lastname: Zimmerman
authors.forename: Mitchell I
authors.initials: MI
authors.lastname: Steinberg
authors.forename: Prabhakar K
authors.initials: PK
authors.lastname: Jadhav
mesh_terms: D006801:Humans; D007211:Indoles / Q000494:pharmacology*; D000451:Mineralocorticoid Receptor Antagonists; D011869:Radioligand Assay
chemical_list: D007211:Indoles; D000451:Mineralocorticoid Receptor Antagonists