title: [Raman spectra of cell from breast cancer patients].
abstract: Raman spectra of normal and cancer cell from breast cancer patients a represented. It is reported that all of the Ramanlines become weak. The intensities of Raman lines 782 and 1 084 cm(-1) of DNA phosphate group and 1 155 and 1 262 cm(-1) of deoxyribosephosphate decrease. The spectral lines 812 cm(-1) of A-type DNA and 979 and 668 cm(-1) disappear, and the 905 cm(-1) peak is shifted to lower frequency by 6 cm(-1). This means that the phosphate backbone of DNA is destroyed to a certain extent and the fissiparity of cancer cell can't be controlled effectively. In addition, the authors found a kind of Raman line 960 cm(-1) concerning calcificationand sclerosis of cancer cell. The results indicate that Raman spectra may offer the experiment basis for the cancer diagnosis and treatment.
authors.affiliation: School of Physics Science and Information Engineering, Liaocheng University, Liaocheng 252059, China.
authors.forename: Xun-Ling
authors.initials: XL
authors.lastname: Yan
authors.forename: Rui-Xin
authors.initials: RX
authors.lastname: Dong
authors.forename: Qiu-Guo
authors.initials: QG
authors.lastname: Wang
authors.forename: Shuang-Feng
authors.initials: SF
authors.lastname: Chen
authors.forename: Zong-Wang
authors.initials: ZW
authors.lastname: Zhang
authors.forename: Xue-Jun
authors.initials: XJ
authors.lastname: Zhang
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
mesh_terms: D001943:Breast Neoplasms / Q000378:metabolism / Q000473:pathology*; D002114:Calcinosis / Q000175:diagnosis; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D006801:Humans; D012598:Sclerosis / Q000175:diagnosis; D013059:Spectrum Analysis, Raman
chemical_list: D004273:DNA, Neoplasm