Biosynthesis of the allene (-)-marasin in Marasmius ramealis.
[1-14C]-E-dehydromatricaria methyl ester and dimethyl [1-14C]-deca-4,6,8-triyne-1,10-dioate are incorporated into the allene (-)-marasin in Marasmius ramealis without scrambling of the 14C label. This and the levels of the incorporations (0.8% and 4.9% respectively) strongly suggests that the above esters, or close relatives, can be converted directly into (-)-marasin in M. ramealis, and that the diyne-allene moiety in this latter compound arises by the rearrangement, under enzymic control, of an alkyltriyne moiety.
Davies
David G
DG
Department of Chemistry, University of Lancaster, Bailrigg, Lancaster, UK LA1 4YA.
Hodge
Philip
P
D000114:Acetylene / Q000031:analogs & derivatives / Q000737:chemistry; D001487:Basidiomycota / Q000378:metabolism*; D003470:Culture Media; D015394:Molecular Structure
D003470:Culture Media; C511518:marasin; D000114:Acetylene