Acrokeratosis paraneoplastica: Bazex syndrome.
Bazex syndrome is a paraneoplastic dermatosis characterized by acral psoriasiform lesions associated with an underlying neoplasm. We present the case of a 64-year-old patient that was diagnosed with squamous cell lung carcinoma after being evaluated for lesions compatible with paraneoplastic acrokeratosis. With a high frequency Bazex syndrome is the earliest marker of an underlying subclinical neoplasm. An early suspicion is of the outmost importance in order to perform a prompt diagnosis of an underlying malignancy. We propose a diagnostic algorithm upon suspicion of acrokeratosis paraneoplastica and review the pathogenesis of this entity.
Valdivielso
M
M
Hospital Gregorio Marañón, C/Doctor Esquerdo, 46, 28007 Madrid, Spain. martavaldivielso@aedv.es
Longo
I
I
Suárez
R
R
Huerta
M
M
Lázaro
P
P
D002294:Carcinoma, Squamous Cell / Q000150:complications*; D006801:Humans; D007642:Keratosis / Q000175:diagnosis / Q000473:pathology*; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000473:pathology*; D013577:Syndrome