title: [Cerebral hemodynamics and statokinetic functions in patients with vertebral basilar vascular insufficiency].
abstract: One hundred and forty-eight patients, aged 29-59 years, with vertebral basilar vascular insufficiency were studied before, during and after betaserc treatment in a dose 48 mg/day during 3 weeks. Along with neurological examination, cerebral dopplerography and computer stabilography methods were used. The main clinical appearances of cerebrovascular pathology of vertebrobasilar system were as follows: vertigo (93.2%), asthenia syndrome (91.2%), autonomic vascular disorders (63.5%) and stato-coordinative disturbances, the latter were represented primarily by disturbances of equilibrium system functions (83.8%). Cerebral dopplerography and computer stabilography were found to be reliable methods for patients with chronic insufficiency of cerebral blood circulation in vertebral basilar area. Drug betaserc (betahystine hydrochloride) effectively stops statokinetic disturbances in patients with discirculatory encelopathy in vertebral basilar area.
authors.forename: D Iu
authors.initials: DIu
authors.lastname: Butko
mesh_terms: D000328:Adult; D001621:Betahistine / Q000008:administration & dosage / Q000627:therapeutic use*; D002560:Cerebrovascular Circulation; D002908:Chronic Disease; D006801:Humans; D008875:Middle Aged; D004856:Postural Balance; D013997:Time Factors; D017585:Ultrasonography, Doppler, Transcranial; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D014715:Vertebrobasilar Insufficiency / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology*; D014717:Vertigo / Q000209:etiology
chemical_list: D014665:Vasodilator Agents; D001621:Betahistine