Human cytomegalovirus infection of a severe-burn patient: evidence for productive self-limited viral replication in blood and lung.
To date, only seroepidemiological data are available on the role of human cytomegalovirus (HCMV) in patients with severe burns. We present the first longitudinal analysis of disseminated HCMV infection with a demonstration of self-limited productive viral replication identified in both the blood and lung of a burn patient.
Hamprecht
Klaus
K
Institute of Medical Virology and Epidemiology of Viral Diseases, Burn Center, University Hospital of Tübingen, Elfriede-Aulhorn-Str 6, D-72076 Tübingen, Germany. kshampre@med.uni-tuebingen.de
Pfau
Mathias
M
Schaller
Hans-Eberhard
HE
Jahn
Gerhard
G
Middeldorp
Jaap M
JM
Rennekampff
Hans-Oliver
HO
D000328:Adult; D001769:Blood / Q000821:virology*; D001803:Blood Transfusion; D001992:Bronchoalveolar Lavage Fluid / Q000821:virology; D002056:Burns / Q000097:blood / Q000150:complications* / Q000821:virology; D003587:Cytomegalovirus / Q000502:physiology*; D003586:Cytomegalovirus Infections / Q000097:blood / Q000209:etiology* / Q000628:therapy; D005260:Female; D006801:Humans; D008168:Lung / Q000821:virology*; D012121:Respiration, Artificial; D016896:Treatment Outcome; D014779:Virus Replication