title: Hyperbaric oxygen as an adjuvant treatment for malignant otitis externa.
abstract: BACKGROUND
  Malignant, or necrotising, otitis externa is a potentially fatal infection of the external ear canal and surrounding soft tissue and bone. It may be complicated by involvement of cranial nerves, principally the facial nerves and the contents of the jugular foramen. It is an uncommon condition mainly found in the elderly or in diabetics.
  
  
  OBJECTIVE
  To assess the effectiveness of adjunctive hyperbaric oxygen treatment for malignant otitis externa.
  
  
  METHODS
  We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library Issue 4, 2003), MEDLINE (January 1966 to April 2004) and EMBASE (January 1985 to April 2004) with pre-specified terms. The date of the last search was 5th April 2004.
  
  
  METHODS
  Randomised controlled trials, involving adults, undergoing hyperbaric oxygen therapy in malignant otitis externa.
  
  
  METHODS
  No identified articles described randomised controlled trials of hyperbaric oxygen therapy in the treatment of malignant otitis externa.
  
  
  RESULTS
  Due to the lack of data no results could be presented.
  
  
  CONCLUSIONS
  No clear evidence exists to demonstrate the efficacy of hyperbaric oxygen therapy when compared to treatment with antibiotics and/or surgery. No data were found to compare rates of complication between the different treatment modalities. Further research is required.
authors.affiliation: Department of Otolaryngology, Norfolk and Norwich University Hospital, Colney Lane, Norwich, Norfolk, UK, NR4 7UY. john.phillips@mac.com
authors.forename: J S
authors.initials: JS
authors.lastname: Phillips
authors.forename: S E M
authors.initials: SE
authors.lastname: Jones
mesh_terms: D001424:Bacterial Infections / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D010032:Otitis Externa / Q000628:therapy*