Overlap of pathology in paralytic rabies and axonal Guillain-Barre syndrome.
We describe clinical and pathological features of a case of paralytic rabies with acute axonal neuropathy that closely resembled axonal Guillain-Barre syndrome. This case emphasizes that there is overlap of both clinical and pathological features in paralytic rabies and axonal Guillain-Barre syndrome. These findings raise the possibility that infectious and autoimmune etiologies can lead to similar morphological changes in the nerves.
Sheikh
Kazim A
KA
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. ksheik@jhmi.edu
Ramos-Alvarez
Manuel
M
Jackson
Alan C
AC
Li
Chun Y
CY
Asbury
Arthur K
AK
Griffin
John W
JW
D016123:Campylobacter jejuni / Q000276:immunology; D004594:Electrophysiology; D004797:Enzyme-Linked Immunosorbent Assay; D017809:Fatal Outcome; D020275:Guillain-Barre Syndrome / Q000473:pathology*; D006801:Humans; D017403:In Situ Hybridization; D008264:Macrophages / Q000473:pathology; D008297:Male; D018613:Microscopy, Confocal; D008854:Microscopy, Electron; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology; D010243:Paralysis / Q000473:pathology; D011818:Rabies / Q000473:pathology*; D013116:Spinal Cord / Q000473:pathology; D013126:Spinal Nerve Roots / Q000473:pathology