title: Iridium complex-catalyzed reaction of 1,6-enynes: cycloaddition and cycloisomerization.
abstract: [reaction: see text] 1,6-Enynes reacted with monoynes to give cyclohexadiene derivatives in the presence of a catalytic amount of [Ir(cod)Cl](2)/ligand. DPPE was most suitable for cycloaddition. Diastereoselective cycloaddition was also possible. In the absence of monoynes, 1,6-enynes cycloisomerized to (Z)-1-alkylidene-2-methylenecyclopentane derivatives. DPPF was most suitable for cycloisomerization. These results are the first examples of highly Z-selective cycloisomerization.
authors.affiliation: Department of Chemistry and Biological Science, Aoyama Gakuin University, Fuchinobe, Sagamihara 229-8558, Japan.
authors.forename: Satoko
authors.initials: S
authors.lastname: Kezuka
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Okado
authors.forename: Eri
authors.initials: E
authors.lastname: Niou
authors.forename: Ryo
authors.initials: R
authors.lastname: Takeuchi