title: Widespread lymph node metastases in a young woman with FIGO stage IA1 squamous cervical cancer.
abstract: BACKGROUND
  Lymphatic and hematologic metastases are rare in microinvasive cervical cancers (FIGO stage IA1), supporting a role for conservative treatment. Cervical conization followed by prolonged surveillance is an accepted treatment in patients with low-risk features and negative surgical margins. This option is particularly appealing for younger or nulliparous patients, in whom fertility may be highly desired.
  
  
  METHODS
  We report a case of a 22-year-old, HIV-negative female with stage IA1 squamous cell cervical carcinoma who was found to have bilateral lymph node metastases in both pelvic and para-aortic distributions after electing to undergo hysterectomy.
  
  
  CONCLUSIONS
  Clinicians treating patients with microinvasive cervical cancer conservatively must be aware of the possibility of lymph node involvement and should consider radiological imaging to look for metastatic disease.
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA. argenta@umn.edu
authors.forename: Peter A
authors.initials: PA
authors.lastname: Argenta
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Kubicek
authors.forename: Kathryn E
authors.initials: KE
authors.lastname: Dusenberry
authors.forename: Patricia L
authors.initials: PL
authors.lastname: Judson
authors.forename: Levi S
authors.initials: LS
authors.lastname: Downs
authors.forename: Linda F
authors.initials: LF
authors.lastname: Carson
authors.forename: Matthew P
authors.initials: MP
authors.lastname: Boente
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery