Association between Wegener's granulomatosis and increased antithyroid antibodies: report of two cases and review of the literature.
We report two patients with severe manifestations of Wegener's granulomatosis, who also had significantly increased antithyroid antibodies. Auto-immune reaction against various human tissue antigens probably explains the association between increased anti-neutrophil cytoplasmic and antithyroid antibodies. The clinicians should include thyroid function and antithyroid antibody tests in the laboratory work up of the patients with Wegener's granulomatosis.
Rosmarakis
E S
ES
Alfa HealthCare, Athens, Greece.
Kapaskelis
A M
AM
Rafailidis
P I
PI
Falagas
M E
ME
D000328:Adult; D000906:Antibodies / Q000276:immunology*; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013961:Thyroid Gland / Q000276:immunology*; D014057:Tomography, X-Ray Computed / Q000379:methods
D000906:Antibodies