title: Class-III malocclusion: genetics or environment? A twins study.
abstract: Etiology of class-III malocclusion is generally believed to be genetic. A wide range of environmental factors have been suggested as contributing factors for the development of class-III malocclusion. Twin study is one of the most effective methods available for investigating genetically determined variables of malocclusion. Discordancy for class-III malocclusion is a frequent finding in dizygotic twins. However, class-III malocclusion discordancy in monozygotic twins is a rare finding. The purpose of this study of monozygotic twins is to assess the genetic and environmental components of variation within the cranio-dento-facial complex.
authors.affiliation: Department of Dental Surgery, All India Institute of Medical Sciences, New Delhi-110029, India.
authors.forename: A K
authors.initials: AK
authors.lastname: Jena
authors.forename: R
authors.initials: R
authors.lastname: Duggal
authors.forename: V P
authors.initials: VP
authors.lastname: Mathur
authors.forename: H
authors.initials: H
authors.lastname: Parkash
mesh_terms: D002508:Cephalometry; D004200:Diseases in Twins / Q000209:etiology / Q000235:genetics*; D005260:Female; D059647:Gene-Environment Interaction; D006801:Humans; D008313:Malocclusion, Angle Class III / Q000209:etiology / Q000235:genetics*; D008445:Maxillofacial Development / Q000235:genetics*; D012720:Severity of Illness Index; D014430:Twins, Monozygotic