title: Selective unilateral parathyroid exploration: an effective treatment for primary hyperparathyroidism.
abstract: BACKGROUND
  Unilateral neck exploration (UNE) is a well-recognized approach in the treatment of primary hyperparathyroidism (PHP). The objective of this study was to review the success of an approach involving UNE guided by preoperative sestamibi (SM) scanning.
  
  
  METHODS
  All data were gathered by retrospective chart review. All patients undergoing surgery for the treatment of primary hyperparathyroidism at a tertiary referral center over a 3-year period were included in the study cohort.
  
  
  RESULTS
  Fifty-two of 80 patients (65%) had an SM scan consistent with a solitary adenoma and were eligible for a UNE, with 57.5% (46/80) undergoing a UNE. Seventy-seven of 80 (96.3%) patients were normocalcemic after initial neck exploration. UNE was curative in 50 of 52 (96.2%) UNE eligible patients and required less operative time than bilateral neck exploration (mean, 60 versus 87 minutes).
  
  
  CONCLUSIONS
  Selective unilateral neck exploration, guided by preoperative SM scanning, is an effective surgical approach for the management of primary hyperparathyroidism.
authors.affiliation: Department of Surgery, Division of General Surgery, St. Paul's Hospital, University of British Columbia, 1081 Burrard Street, Vancouver, British Columbia BC V6Z 1Y6, Canada. cbaliski@providencehealth.bc.ca
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Baliski
authors.forename: James K
authors.initials: JK
authors.lastname: Stewart
authors.forename: Donald W
authors.initials: DW
authors.lastname: Anderson
authors.forename: Sam M
authors.initials: SM
authors.lastname: Wiseman
authors.forename: Samuel P
authors.initials: SP
authors.lastname: Bugis
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D016105:Parathyroidectomy / Q000379:methods; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D017256:Technetium Tc 99m Sestamibi
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi