A catalytic enantioselective hetero Diels-Alder approach to the C20-C32 segment of the phorboxazoles.
[reaction: see text] An efficient synthesis of the C20-C32 segment of the phorboxazoles has been achieved using an enantioselective hetero Diels-Alder reaction catalyzed by Jacobsen's Cr(III) amino indanol Schiff base catalyst.
Lucas
Brian S
BS
Department of Chemistry, University of Wisconsin, 1101 University Avenue, Madison, Wisconsin 53706-1396, USA.
Luther
Laura M
LM
Burke
Steven D
SD
D002384:Catalysis; D002857:Chromium / Q000737:chemistry; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000737:chemistry; D007202:Indicators and Reagents; D015394:Molecular Structure; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry; D012545:Schiff Bases / Q000737:chemistry
D006576:Heterocyclic Compounds, 4 or More Rings; D007202:Indicators and Reagents; D010080:Oxazoles; D012545:Schiff Bases; D002857:Chromium; C408887:phorboxazole A