Cytomegalovirus retinitis after immune reconstitution.
Cytomegalovirus (CMV) infection is the most common opportunistic infection that affects the retina in HIV-positive patients; it typically occurs in the setting of severe immune suppression (CD4 count less than 50 cell/microL). We present a case report of an HIV-infected patient in whom recurrent CMV retinitis developed after HAART and apparent immune reconstitution (CD4 count of greater than 500 cells/microL). This case report underscores that CMV infection may occur despite high CD4 counts among patients who experience only partial immune reconstitution.
Crum
Nancy F
NF
HIV Clinic, Department of Internal Medicine, Division of Infectious Diseases, Naval Medical Center, San Diego, California, USA.
Blade
Kent A
KA
D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D017726:Cytomegalovirus Retinitis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D015658:HIV Infections / Q000188:drug therapy; D006801:Humans