Synthesis, properties and thermal studies of oxorhenium(V) complexes with 3-hydrazino-5,6-diphenyl-1,2,4-triazine, benzimidazolethione and 2-hydrazinobenzimidazole. Mixed ligand complexes, pyrolytical products and biological activity.
A series of biologically active complexes of oxorhenium(V), were prepared by using the organic ligands 3-hydrazino-5,6-diphenyl-1,2,4-triazine (HL1), benzimidazolethione (H2L2) and 2-hydrazinobenzimidazole (H2L3). The mixed ligand complexes of oxorhenium(V) with the previous ligands and one of the following ligands: NH4SCN, 1,10-phenanthroline (1,10-phen), 8-hydroxyquinoline (8-OHquin) or glycine (Gly), were isolated. All the binary and mixed ligand complexes have monomeric structures and exist in the octahedral configuration. Thermal studies on these complexes showed the possibility of structural transformation from mononuclear into binuclear ones. The structures of all complexes and the corresponding thermal products were elucidated by elemental analyses, IR, electronic absorption and 1H NMR spectra, magnetic moments, conductance and TG-DSC measurements. The antifungal activities of the metal complexes towards Alternaria alternata and Aspergilus niger were tested and showed comparable behaviour with some well known antibiotics.
Mashaly
M M
MM
Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo, Egypt. mashalym@hotmail.com
El-Shafiy
H F
HF
El-Maraghy
S B
SB
Habib
H A
HA
D000528:Alternaria / Q000378:metabolism; D000935:Antifungal Agents / Q000494:pharmacology; D001234:Aspergillus niger; D001562:Benzimidazoles / Q000737:chemistry*; D002152:Calorimetry, Differential Scanning; D005998:Glycine / Q000737:chemistry; D006358:Hot Temperature; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008956:Models, Chemical; D008968:Molecular Conformation; D012211:Rhenium / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013816:Thermodynamics; D013861:Thiocyanates / Q000737:chemistry; D014227:Triazines / Q000737:chemistry*
D000935:Antifungal Agents; D001562:Benzimidazoles; D008024:Ligands; D013861:Thiocyanates; D014227:Triazines; C048905:5,6-diphenyl-1,2,4-triazine-3-thiol; D012211:Rhenium; C031000:benzimidazole; D005998:Glycine