title: Quantification of adenovirus in the lower respiratory tract of patients without clinical adenovirus-related respiratory disease.
abstract: Adenovirus in bronchoalveolar lavage fluid samples from 50 patients without adenovirus-related illness was quantified. In 49 patients, adenovirus was found (median load, 3.3 x 10(3) copies/microg of DNA). The adenovirus load was inversely related to lymphocyte count (Pearson correlation coefficient r = -0.311; P = .03) and was significantly greater in immunosuppressed patients than in immunocompetent patients (5.1 x 10(3) vs. 2.0 x 10(3) copies/microg of DNA; P = .028).
authors.affiliation: Department of Medicine, University of Hong Kong, Hong Kong.
authors.forename: Anskar Yu-Hung
authors.initials: AY
authors.lastname: Leung
authors.forename: Maggie
authors.initials: M
authors.lastname: Chan
authors.forename: Vincent Chi-Chung
authors.initials: VC
authors.lastname: Cheng
authors.forename: Kwok-Yung
authors.initials: KY
authors.lastname: Yuen
authors.forename: Yok-Lam
authors.initials: YL
authors.lastname: Kwong
mesh_terms: D000260:Adenoviruses, Human / Q000302:isolation & purification*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001992:Bronchoalveolar Lavage Fluid / Q000821:virology; D002353:Carrier State / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006801:Humans; D007121:Immunocompetence; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D012137:Respiratory System / Q000821:virology*; D019562:Viral Load
chemical_list: D004279:DNA, Viral