[Multiple pulmonary nodules and amiodarone. KL-6 as a new diagnostic tool].
Pulmonary toxicity is an infrequent but serious adverse event in patients treated with amiodarone. The main problem at present is that we lack the necessary tools to detect this event or predict which patients will develop pulmonary toxicity. Serum Krebs von den Lungen-6 (KL-6) has been previously recognized as a marker for the activity of diffuse interstitial lung disease. We describe a patient with pulmonary toxicity due to amiodarone with increased blood levels of this new marker, and discuss the clinical usefulness of this new diagnostic tool.
Bernal Morell
Enrique
E
Servicio de Medicina Interna, Hospital Ramón y Cajal, Madrid, España.
Hernández Madrid
Antonio
A
Marín Marín
Irene
I
Rodríguez Pena
Rebeca
R
González Gordaliza
María C
MC
Moro
Concepción
C
D000368:Aged; D000638:Amiodarone / Q000009:adverse effects*; D000941:Antigens / Q000097:blood*; D000951:Antigens, Neoplasm; D005260:Female; D006023:Glycoproteins / Q000097:blood*; D006801:Humans; D008171:Lung Diseases / Q000097:blood / Q000139:chemically induced* / Q000175:diagnosis*; D018396:Mucin-1; D009077:Mucins
D000941:Antigens; D000951:Antigens, Neoplasm; D006023:Glycoproteins; C060192:MUC1 protein, human; D018396:Mucin-1; D009077:Mucins; D000638:Amiodarone