Photo-onycholysis due to sparfloxacin.
This paper describes a case of sparfloxacin-induced photodermatitis associated with photo-onycholysis in a 36-year-old man. He was being treated with sparfloxacin, streptomycin, ethambutol and pyrazinamide for pulmonary tuberculosis. He developed an exaggerated sunburn-like rash over the face and the dorsa of hands and feet, and painful onycholysis of finger- and toe-nails. Withdrawal of sparfloxacin resulted in resolution of the skin rash and nail tenderness.
Mahajan
Vikram K
VK
Department of Dermatology, Venereology and Leprosy, Indira Gandhi Medical College, Shimla, India.
Sharma
Nand Lal
NL
D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects*; D003937:Diagnosis, Differential; D024841:Fluoroquinolones / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009262:Nails / Q000473:pathology*; D010787:Photosensitivity Disorders / Q000139:chemically induced / Q000175:diagnosis* / Q000473:pathology; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
D000995:Antitubercular Agents; D024841:Fluoroquinolones; C061363:sparfloxacin