Surface analyses and immune reactivities of major cell wall-associated proteins of group a streptococcus.
A proteomic analysis was undertaken to identify cell wall-associated proteins of Streptococcus pyogenes. Seventy-four distinct cell wall-associated proteins were identified, 66 of which were novel. Thirty-three proteins were immunoreactive with pooled S. pyogenes-reactive human antisera. Biotinylation of the GAS cell surface identified 23 cell wall-associated proteins that are surface exposed.
Cole
Jason N
JN
School of Biological Sciences, University of Wollongong, Wollongong, NSW 2522, Australia.
Ramirez
Ruben D
RD
Currie
Bart J
BJ
Cordwell
Stuart J
SJ
Djordjevic
Steven P
SP
Walker
Mark J
MJ
D001426:Bacterial Proteins / Q000276:immunology* / Q000378:metabolism*; D002473:Cell Wall / Q000378:metabolism*; D015180:Electrophoresis, Gel, Two-Dimensional; D006801:Humans; D040901:Proteomics; D013297:Streptococcus pyogenes / Q000737:chemistry* / Q000276:immunology
D001426:Bacterial Proteins