title: [99mTc-HMPAO brain SPECT in a case of HSV encephalitis].
abstract: We present a case of encephalitis caused by Herpes Simplex Virus in a 57 year old woman. The acute picture was suggestive of viral infection without associated neurological symptoms. Due to the posterior appearance of neurological focality, cerebral spinal fluid (CSF) was analyzed. It showed pleocytosis and lymphocytosis, inflammatory process data, and serological test with positivity for Simple Herpes Virus (SHV) subtypes I and II. During admission, other complementary tests were performed: EEG, CT, MRI, cerebral perfusion SPECT; the later supplied significant data regarding anatomical neuroimaging (CT, MRI) in regards to bihemispheral extension of the encephalic condition. Furthermore, after clinical discharge, persistent metabolic abnormality was demonstrated in temporal cortex, responsible for concomitant mixed aphasia.
authors.affiliation: Servicios de Medicina Nuclear, Hospital Meixoeiro, 36200 Vigo. luis.campos.villarino@sergas.es
authors.forename: L
authors.initials: L
authors.lastname: Campos Villarino
authors.forename: A
authors.initials: A
authors.lastname: Serena Puig
authors.forename: J
authors.initials: J
authors.lastname: Romero López
authors.forename: J M
authors.initials: JM
authors.lastname: Nogueiras Alonso
authors.forename: J
authors.initials: J
authors.lastname: Outomuro Pérez
mesh_terms: D000914:Antibodies, Viral / Q000097:blood; D001037:Aphasia / Q000209:etiology; D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology / Q000821:virology; D002555:Cerebrospinal Fluid / Q000166:cytology; D002560:Cerebrovascular Circulation; D004569:Electroencephalography; D020803:Encephalitis, Herpes Simplex / Q000134:cerebrospinal fluid / Q000150:complications / Q000000981:diagnostic imaging* / Q000821:virology; D005260:Female; D018259:Herpesvirus 1, Human / Q000276:immunology / Q000302:isolation & purification; D018258:Herpesvirus 2, Human / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D007964:Leukocytosis / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D019275:Radiopharmaceuticals / Q000627:therapeutic use*; D019690:Technetium Tc 99m Exametazime; D013702:Temporal Lobe / Q000000981:diagnostic imaging / Q000473:pathology; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: D000914:Antibodies, Viral; D019275:Radiopharmaceuticals; D019690:Technetium Tc 99m Exametazime