Detection of RNA nucleobase metalation by NMR spectroscopy.
Nucleic acids possess several metal cation recognition sites, including phosphates, nucleobases and possibly riboses. This article focuses on the detection of nucleobase-metal interactions by NMR spectroscopy.
Tanaka
Yoshiyuki
Y
Laboratory of Molecular Transformation, Graduate School of Pharmaceutical Sciences, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan. tanaka@mail.pharm.tohoku.ac.jp
Taira
Kazunari
K
D020029:Base Pairing; D001665:Binding Sites; D001667:Binding, Competitive; D008670:Metals / Q000737:chemistry*; D008958:Models, Molecular; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry*; D016337:RNA, Catalytic / Q000737:chemistry
D008670:Metals; D016337:RNA, Catalytic; C427204:hammerhead ribozyme; D012313:RNA