Anisotropic elastic properties of microtubules.
We review and model the experimental parameters which characterize elastic properties of microtubules. Three macroscopic estimates are made of the anisotropic elastic moduli, accounting for the molecular forces between tubulin dimers: for a longitudinal compression of a microtubule, for a lateral force and for a shearing force. These estimates reflect the anisotropies in these parameters observed in several recent experiments.
Tuszyński
J A
JA
Department of Physics, University of Alberta, T6G 2J1, Edmonton, Alberta, Canada, jtus@phys.ualberta.ca
Luchko
T
T
Portet
S
S
Dixon
J M
JM
D000818:Animals; D016880:Anisotropy; D003198:Computer Simulation; D004548:Elasticity; D006801:Humans; D008870:Microtubules / Q000737:chemistry* / Q000502:physiology* / Q000648:ultrastructure; D008954:Models, Biological; D008956:Models, Chemical; D008958:Models, Molecular; D046912:Multiprotein Complexes / Q000737:chemistry / Q000502:physiology / Q000648:ultrastructure; D011485:Protein Binding; D013314:Stress, Mechanical; D014404:Tubulin / Q000737:chemistry* / Q000502:physiology* / Q000648:ultrastructure
D046912:Multiprotein Complexes; D014404:Tubulin