title: Epilepsy and variation in the frontal lobe artery.
abstract: A patient with a rare variation of fronto-orbital artery (FOA) that developed generalized tonic and clonic seizures is reported. The epilepsy focus was in her left frontal region, where blood was supplied by the contralateral fronto-orbital artery. The region was vulnerable to ischemic changes due to a decrease in blood CO2 gas caused by an increase in endogenous progesterone in the luteal period. The anomaly illustrates an important mechanism of ischemia in epilepsy.
authors.affiliation: Department of Neurosurgery, Shimane University School of Medicine, 89-1 Enya-cho, Izumo, Shimane 693-8501, Japan. nogeka@med.shimane-u.ac.jp
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Maruyama
authors.forename: Atsushi
authors.initials: A
authors.lastname: Fukuma
authors.forename: Ikuo
authors.initials: I
authors.lastname: Ihara
authors.forename: Seiichi
authors.initials: S
authors.lastname: Ando
authors.forename: Kouzo
authors.initials: K
authors.lastname: Moritake
mesh_terms: D000328:Adult; D020771:Anterior Cerebral Artery / Q000473:pathology*; D001165:Arteriovenous Malformations / Q000150:complications / Q000532:radiotherapy; D001784:Blood Gas Analysis / Q000379:methods; D002245:Carbon Dioxide / Q000097:blood; D002533:Cerebral Angiography / Q000379:methods; D004569:Electroencephalography / Q000379:methods; D017034:Epilepsy, Frontal Lobe / Q000209:etiology / Q000473:pathology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods
chemical_list: D002245:Carbon Dioxide