title: An increase of BNP levels in massive pulmonary embolism and the reduction in response to the acute treatment.
abstract: Type B Natriuretic Peptide (BNP) is a neurohormone that is secreted from the cardiac ventricles in response to dilatation or an increase of pressure. Right ventricle dysfunction is seen in pulmonary embolism patients, but it may be hard to diagnose. Echocardiography is the most sensitive means of diagnosis for acute right ventricle dysfunction. However, echocardiography is also limited in some ways. BNP levels may increase with right ventricle dysfunction when the patients is in bed and decrease with treatment. We presented a case study in which diagnosed with mitral valve regurgitation, pulmonary embolism and pregnant for 1.5 months. Initial BNP levels of 633 pg/ml decreased to 233, 65.2, 58.4 levels respectively which was parallel to improvements in the clinical state and right ventricle function detected in echocardiography. We used a rapid bedside test for determination of BNP.
authors.affiliation: Department of Internal Medicine, Ondokuz Mayis University, School of Medicine, 55139 Samsun, Turkey. leventaltintop@hotmail.com
authors.forename: Levent
authors.initials: L
authors.lastname: Altintop
authors.forename: Turker
authors.initials: T
authors.lastname: Yardan
authors.forename: Basar
authors.initials: B
authors.lastname: Cander
authors.forename: Serhat
authors.initials: S
authors.lastname: Findik
authors.forename: Ozcan
authors.initials: O
authors.lastname: Yilmaz
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000150:complications / Q000628:therapy; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D011655:Pulmonary Embolism / Q000097:blood* / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D016896:Treatment Outcome; D018497:Ventricular Dysfunction, Right / Q000097:blood / Q000175:diagnosis / Q000209:etiology / Q000628:therapy
chemical_list: D020097:Natriuretic Peptide, Brain