title: [Hospital practice and prion risks].
abstract: Procedures applicable in France for the prevention of prion diseases were first implemented in 1995, resulting from the threat of an epidemic extension of Creutzfeldt-Jakob Disease (CJD) following contamination resulting from the use of extracted growth hormone. It was found later that the bovine disease could infect humans via foodstuffs, and the human variant of the disease (v-CJD) transmissible through lymphoid formations was described in 1996. This led to generalizing precautions to a larger number of medical interventions, taking into account the risk for a population more broadly exposed to contamination. The principles for managing these new risks are described, as well for the use of medical devices or in patient as pathology laboratories.
authors.affiliation: Laboratoire des contrôles biologiques, pharmacie centrale des hôpitaux, université Paris-V, France. darbord@pharmacie.univ-paris5.fr
authors.forename: J-C
authors.initials: JC
authors.lastname: Darbord
authors.forename: J-J
authors.initials: JJ
authors.lastname: Hauw
mesh_terms: D000818:Animals; D001344:Autopsy; D002417:Cattle; D003264:Containment of Biohazards / Q000379:methods / Q000592:standards; D003428:Cross Infection / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D003666:Decontamination / Q000379:methods / Q000592:standards; D004203:Disinfection / Q000379:methods / Q000592:standards; D016643:Encephalopathy, Bovine Spongiform / Q000635:transmission; D019723:Endoscopes; D004866:Equipment Contamination / Q000517:prevention & control; D017743:Equipment Reuse; D004865:Equipment and Supplies, Hospital; D017408:Guidelines as Topic; D006801:Humans; D017744:Medical Waste Disposal / Q000379:methods / Q000592:standards; D016134:Organizational Policy; D017096:Prion Diseases / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D011328:Prions / Q000032:analysis; D012306:Risk
chemical_list: D017744:Medical Waste Disposal; D011328:Prions