Fluorinated alpha-aminophosphonates--a new type of irreversible inhibitors of serine hydrolases.
Makhaeva
G F
GF
Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Moscow oblast, 142432 Russia.
Malygin
V V
VV
Aksinenko
A Yu
AY
Sokolov
V B
VB
Strakhova
N N
NN
Rasdolsky
A N
AN
Richardson
R J
RJ
Martynov
I V
IV
D001671:Biochemistry / Q000379:methods; D002800:Cholinesterase Inhibitors / Q000737:chemistry / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005461:Fluorine / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D008962:Models, Theoretical; D063065:Organophosphonates / Q000494:pharmacology*; D012697:Serine Endopeptidases / Q000737:chemistry / Q000378:metabolism*; D013997:Time Factors
D002800:Cholinesterase Inhibitors; D004791:Enzyme Inhibitors; D063065:Organophosphonates; D005461:Fluorine; D012697:Serine Endopeptidases