Oncocytic renal neoplasms: diagnostic considerations.
Advances in our understanding of renal neoplasia have resulted in recognition of numerous tumors that are composed predominantly of cells with abundant eosinophilic cytoplasm. This article discusses the features of renal oncocytoma (including oncocytosis), chromophobe renal cell carcinoma (RCC), and clear cell RCC; explores the relationship between renal oncocytoma and chromophobe RCC; briefly discusses other tumors with abundant eosinophilic cytoplasm; and emphasizes the differential diagnosis of such tumors.
Abrahams
Neil A
NA
Department of Pathology and Microbiology, The University of Nebraska Medical Center, Omaha, NE 68198-7549, USA. nabrahams@unmc.edu
Tamboli
Pheroze
P
D018249:Adenoma, Oxyphilic / Q000175:diagnosis* / Q000473:pathology; D002292:Carcinoma, Renal Cell / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D004804:Eosinophils / Q000473:pathology; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000473:pathology; D009386:Neoplastic Syndromes, Hereditary / Q000473:pathology; D011506:Proteins / Q000235:genetics; D011518:Proto-Oncogene Proteins; D025521:Tumor Suppressor Proteins
C476078:FLCN protein, human; D011506:Proteins; D011518:Proto-Oncogene Proteins; D025521:Tumor Suppressor Proteins