The dynamical way to mutation-selection balance of an infinite population evolving on a truncated fitness landscape.
This paper presents the exact analytical solution, valid for all generations and initial conditions, for the frequency distribution of haploids with infinite-sites genome carrying a given number of mutations in a population evolving deterministically on a truncated fitness landscape. This landscape is a generalization of the single sharp peak one, widely used in quasispecies theory, although here there are no reverse mutations.
Maia
Leonardo P
LP
Instituto de Ciências Matemáticas e de Computação, Universidade de São Paulo, 13560-970 São Carlos, SP, Brazil. lpmaia@icmc.usp.br
D000818:Animals; D005075:Biological Evolution; D005828:Genetics, Population; D008957:Models, Genetic; D009154:Mutation; D011157:Population Dynamics; D012641:Selection, Genetic