title: Bowel function following insertion of self-expanding metallic stents for palliation of colorectal cancer.
abstract: OBJECTIVE
  Self-expanding metallic stents (SEMS) are an important addition to the treatment of large bowel obstruction. The aim of this study was firstly to assess bowel function following SEMS placement and secondly to identify any potential factors which might aid in the prediction of technical failure of stent insertion.
  
  
  METHODS
  A review of all patients undergoing attempted SEMS placement for palliation of malignant left-sided colorectal obstruction over a four-year period (1st May 2000-30th April 2004) was performed.
  
  
  RESULTS
  Twenty-one patients (12 male) with a median age of 76 years (range 48-92 years) were included, 11 with metastatic disease and 10 severe comorbidity. SEMS insertion was technically successful in 16 (76%) of 21 cases. Contrast successfully passed through the obstructing lesion in all 16 cases where SEMS placement was technically successful. It only passed through 1 of 5 cases where stenting was not possible (P = 0.0008, Fisher's Exact test). Complications included colonic perforation (1 case), stent migration (1 case) and tumour ingrowth requiring a second stent (1 case). Median survival after SEMS was 12 months (range 1-30 months), and 9 patients died during follow-up. Median bowel frequency following SEMS was 3.5 times per day (range 1-7). Eight patients always passed a liquid stool, 3 others regularly required laxatives and one further patient with poor function after stenting requested a defunctioning stoma.
  
  
  CONCLUSIONS
  Failure of contrast to pass through the obstructing lesion may predict those cases where stenting will not be technically possible. Median survival following SEMS insertion is encouraging in this series, but bowel function is often poor. Expected bowel function should be discussed fully when consenting patients for a SEMS, particularly those with metastatic disease who are otherwise fit for resectional surgery.
authors.affiliation: Department of Colorectal Surgery, Gloucestershire Royal Hospital, Gloucester, UK.
authors.forename: R J
authors.initials: RJ
authors.lastname: Davies
authors.forename: I Barros
authors.initials: IB
authors.lastname: D'Sa
authors.forename: M E
authors.initials: ME
authors.lastname: Lucarotti
authors.forename: A L
authors.initials: AL
authors.lastname: Fowler
authors.forename: A
authors.initials: A
authors.lastname: Tottle
authors.forename: P
authors.initials: P
authors.lastname: Birch
authors.forename: T A
authors.initials: TA
authors.lastname: Cook
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003106:Colon / Q000503:physiopathology* / Q000601:surgery; D015179:Colorectal Neoplasms / Q000150:complications / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005769:Gastrointestinal Motility / Q000502:physiology*; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010166:Palliative Care / Q000379:methods*; D011474:Prosthesis Design; D019919:Prosthesis Implantation / Q000295:instrumentation* / Q000401:mortality; D012189:Retrospective Studies; D015607:Stents; D015996:Survival Rate; D016896:Treatment Outcome