title: RNAi therapy: dominant disease gene gets silenced.
authors.affiliation: Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation St-817 LRB, Worcester, MA 01655, USA. Zuoshang.Xu@unmassmed.edu
authors.forename: Z
authors.initials: Z
authors.lastname: Xu
authors.forename: X G
authors.initials: XG
authors.lastname: Xia
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics / Q000628:therapy*; D000818:Animals; D020868:Gene Silencing; D005799:Genes, Dominant; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors / Q000008:administration & dosage / Q000235:genetics; D006801:Humans; D016086:Lentivirus / Q000235:genetics; D051379:Mice; D008822:Mice, Transgenic; D023421:Models, Animal; D009154:Mutation; D034622:RNA Interference; D034741:RNA, Small Interfering; D013482:Superoxide Dismutase / Q000235:genetics*; D000072105:Superoxide Dismutase-1
chemical_list: D034741:RNA, Small Interfering; C000606290:SOD1 protein, human; C000606291:Sod1 protein, mouse; D013482:Superoxide Dismutase; D000072105:Superoxide Dismutase-1