title: Looking at an oft-overlooked part of the eye: a new perspective on ciliary body development in chick.
abstract: The ciliary body is an essential tissue for the development and homeostasis of the vertebrate eye. Embryonically, the epithelial portion of the ciliary body derives from the neuroepithelium of the optic cup, however, it differentiates into a secretory tissue and produces an aqueous humor that sustains the lens and cornea, and maintains the requisite pressure within the orb. The unique differentiation of this portion of the optic cup is little understood. This article reviews what is known about the development of the ciliary body and presents some preliminary findings that may lead to a new model for the formation of the ciliary body.
authors.affiliation: Department of Neurosurgical Research, Box 0520, University of California, San Francisco, CA 94143, USA. jdhyer@itsa.ucsf.edu
authors.forename: Jeanette
authors.initials: J
authors.lastname: Hyer
mesh_terms: D000818:Animals; D002450:Cell Communication / Q000502:physiology*; D002454:Cell Differentiation / Q000502:physiology*; D002642:Chick Embryo; D002645:Chickens; D002924:Ciliary Body / Q000166:cytology / Q000196:embryology* / Q000378:metabolism; D024081:Collagen Type IX / Q000378:metabolism; D004627:Embryonic Induction / Q000502:physiology*; D004847:Epithelial Cells / Q000166:cytology / Q000378:metabolism*; D018507:Gene Expression Regulation, Developmental / Q000502:physiology; D007908:Lens, Crystalline / Q000166:cytology / Q000196:embryology* / Q000378:metabolism; D012160:Retina / Q000166:cytology / Q000196:embryology / Q000378:metabolism
chemical_list: D024081:Collagen Type IX