Surprising twists to exocyst function.
What do neurons use the exocyst complex for? In this issue of Neuron, using mutations in one exocyst component, Mehta et al. reach the surprising conclusion that exocyst function is divisible: different components play distinct roles. These studies also suggest that the exocyst may regulate membrane insertion of cell adhesion molecules required for synaptic partner choice.
Clandinin
Thomas R
TR
Department of Neurobiology, Stanford University, Stanford, CA 94305, USA.
D008565:Membrane Proteins / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D021381:Protein Transport / Q000502:physiology*
D008565:Membrane Proteins