title: Neuropsychiatric systemic lupus erythematosus: correlation of brain MR imaging, CT, and SPECT.
abstract: Systemic lupus erythematosus (SLE) patients frequently present with neuropsychiatric symptoms. We conducted an imaging study with magnetic resonance (MR) imaging, computed tomography (CT), and single photon emission CT (SPECT) in 23 patients with SLE, 13 with major neuropsychiatric symptoms (NPSLE) and 10 without (non-NPSLE). The most frequent brain imaging findings were seen with MR imaging and were more prevalent in NPSLE: high signal intensity focal white matter lesions, infarcts in the cortex and pons, and basal ganglia lesions.
authors.affiliation: Department of Radiology, Hospital Mae de Deus, Porto Alegre, Brazil. marcelorad@hotmail.com
authors.forename: Marcelo R
authors.initials: MR
authors.lastname: Abreu
authors.forename: Andréia
authors.initials: A
authors.lastname: Jakosky
authors.forename: Marcelo
authors.initials: M
authors.lastname: Folgerini
authors.forename: João Carlos T
authors.initials: JC
authors.lastname: Brenol
authors.forename: Ricardo M
authors.initials: RM
authors.lastname: Xavier
authors.forename: Flávio
authors.initials: F
authors.lastname: Kapczinsky
mesh_terms: D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D020945:Lupus Vasculitis, Central Nervous System / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed