title: Rhodium-catalyzed intramolecular conjugate addition of vinylstannanes to 2,3-dihydro-4-pyridones. An efficient route to stereoselective construction of indolizidines.
abstract: [reaction: see text] [RhCl(cod)](2) is an effective catalyst for the intramolecular conjugate addition of vinylstannanes to 2,3-dihydro-4-pyridones under neutral conditions at room temperature. The reaction occurs in good yields, giving indolizidine skeletons with excellent diastereoselectivity. A stereochemical outcome observed in these cyclizations is proposed.
authors.affiliation: Institute of Organic Chemistry, Polish Academy of Sciences, 01-224 Warsaw, Poland.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Dziedzic
authors.forename: Marta
authors.initials: M
authors.lastname: Małecka
authors.forename: Bartłomiej
authors.initials: B
authors.lastname: Furman