title: [A patient with heart failure and a new murmur: not always a valvular problem].
abstract: A 78-year-old man presented with dyspnoea and a 57-year-old with chest pain. Both had a history of coronary atherosclerosis and were now found to have a cardiac murmur. They proved to have a ventricular septal rupture (VSR) that had not been recognized as such. In the older man, the myocardial infarction that caused the VSR had initially not been recognized and in both men the clinical course was erroneously attributed to heart failure caused by myocardial infarction alone. Both underwent surgical correction of the VSR; the older man died due to postoperative intestinal necrosis, the younger man recovered. Patients with a high cardiac-risk profile, atypical chest pain, symptoms ofdyspnoea and a new specific murmur should be suspected of having a VSR. Early recognition and treatment of VSR may reduce mortality significantly.
authors.affiliation: Isala Klinieken, locatie Weezenlanden, Groot Weezenland 2o, 8o11 JW Zwolle.
authors.forename: H C
authors.initials: HC
authors.lastname: Groenewegen
authors.forename: G J
authors.initials: GJ
authors.lastname: Brandon Bravo Bruinsma
authors.forename: J H E
authors.initials: JH
authors.lastname: Dambrink
mesh_terms: D000368:Aged; D002637:Chest Pain / Q000209:etiology; D003324:Coronary Artery Disease / Q000150:complications; D017809:Fatal Outcome; D006333:Heart Failure / Q000150:complications*; D006337:Heart Murmurs / Q000209:etiology; D006342:Heart Rupture, Post-Infarction / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006346:Heart Septum / Q000293:injuries / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012307:Risk Factors