title: Cordycedipeptide A, a new cyclodipeptide from the culture liquid of Cordyceps sinensis (Berk.) Sacc.
abstract: A new cyclodipeptide named as cordycedipeptide A, a new natural compound and two known compound were isolated from the culture liquid of Cordyceps sinensis (BERK.) SACC. Their structures were elucidated as 3-acetamino-6-isobutyl-2,5-dioxopiperazine (1), 3-isopropyl-6-isobutyl-2,5-dioxopiperazine (2) and 3,6-di(4-hydroxy)benzyl-2,5-dioxopiperazine (3) by 1D and 2D-NMR techniques. The cytotoxic assay showed compound 1 had the cytotoxic activities to L-929, A375, and Hela.
authors.affiliation: Department of Traditional Chinese Medicines, Shenyang Pharmaceutical University, Shenyang 110016, China.
authors.forename: Jing-Ming
authors.initials: JM
authors.lastname: Jia
authors.forename: Xiao-Chi
authors.initials: XC
authors.lastname: Ma
authors.forename: Chun-Fu
authors.initials: CF
authors.lastname: Wu
authors.forename: Li-Jun
authors.initials: LJ
authors.lastname: Wu
authors.forename: Gao-sheng
authors.initials: GS
authors.lastname: Hu
mesh_terms: D032661:Cordyceps / Q000737:chemistry / Q000302:isolation & purification*; D003470:Culture Media / Q000737:chemistry / Q000302:isolation & purification*; D004151:Dipeptides / Q000737:chemistry* / Q000302:isolation & purification*; D006367:HeLa Cells; D006801:Humans
chemical_list: D003470:Culture Media; D004151:Dipeptides