Adiponectin levels and cardiovascular risk factors in Japanese men with type 2 diabetes.
Several cardiovascular risk factors correlate with adiponectin levels. It is not known whether total homocysteine, folate and gamma-glutamyl transferase levels correlate with adiponectin. We cross-sectionally analyzed the association between adiponectin and these cardiovascular risk factors in diabetic patients. One hundred and two male inpatients with type 2 diabetes without overt nephropathy or insulin use were studied. In a regression analysis of the quartiles of adiponectin, plasma levels of adiponectin were associated positively with HDL-cholesterol and age, and inversely with body mass index and HbA1c, but not with total homocysteine, folate or gamma-glutamyl transferase. Non-traditional cardiovascular risk factors such as homocysteine and folate levels were not associated with adiponectin levels in male type 2 diabetic patients who are not subject to insulin therapy.
Sakuta
Hidenari
H
Department of Internal Medicine, Self-Defense Forces Central Hospital, Ikejiri, Tokyo, Japan.
Suzuki
Takashi
T
Yasuda
Hiroko
H
Ito
Teizo
T
D052242:Adiponectin; D000328:Adult; D000375:Aging; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications; D005492:Folic Acid / Q000097:blood; D006442:Glycated Hemoglobin / Q000032:analysis; D006710:Homocysteine / Q000097:blood; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000097:blood*; D007564:Japan; D007958:Leukocyte Count; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012907:Smoking / Q000097:blood; D005723:gamma-Glutamyltransferase / Q000097:blood
D052242:Adiponectin; D008076:Cholesterol, HDL; D005492:Folic Acid; D006442:Glycated Hemoglobin; D006710:Homocysteine; D036341:Intercellular Signaling Peptides and Proteins; D008055:Lipids; D005723:gamma-Glutamyltransferase