Listeria monocytogenes skin infection with cerebritis and haemophagocytosis syndrome in a bone marrow transplant recipient.
In this report, we describe unusual and unreported manifestations of Listeria monocytogenes infection in a bone marrow transplant recipient, including cutaneous infection with an hamophagocytosis syndrome and cerebritis. L. monocytogenes occurred despite a broad spectrum antibiotherapy. L. monocytogenes was isolated from a skin biopsy. Outcome was favorable with amoxicillin and gentamicin therapy. L. monocytogenes infection should be suspected in patients with cerebritis despite large spectrum antibiotherapy and this report underscores the usefulness of skin biopsies in febrile immunocompromised patients.
Lambotte
O
O
Department of Haematology, Necker Hospital, Paris, France. olivier.lambotte@bct.ap-hop-paris.fr
Fihman
V
V
Poyart
C
C
Buzyn
A
A
Berche
P
P
Soumelis
V
V
D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D004660:Encephalitis / Q000209:etiology*; D015616:Histiocytosis, Non-Langerhans-Cell / Q000209:etiology*; D006801:Humans; D008089:Listeria monocytogenes / Q000302:isolation & purification; D008088:Listeriosis / Q000150:complications*; D008297:Male; D017192:Skin Diseases, Bacterial / Q000150:complications*