Bone marrow embolism in sickle cell disease: a review.
The fat embolism syndrome is an important complication of patients with sickle cell hemoglobinopathies because of severe morbidity and mortality. Our recent experience with three cases that survived with intensive supportive care and prompt use of transfusion stimulates this review. A high index of suspicion, prompt use of diagnostic tools, and aggressive clinical management are the keys to a successful outcome.
Dang
Nghia C
NC
Department of Medicine, University of California-San Diego, School of Medicine, San Diego, California, USA.
Johnson
Cage
C
Eslami-Farsani
Mahmoud
M
Haywood
L Julian
LJ
D000755:Anemia, Sickle Cell / Q000150:complications* / Q000473:pathology; D001853:Bone Marrow / Q000098:blood supply* / Q000473:pathology; D004617:Embolism / Q000473:pathology*; D004620:Embolism, Fat / Q000473:pathology; D009336:Necrosis