Treatment of low-grade gliomas in children: an update.
Pediatric low-grade gliomas are a heterogeneous group of tumors that require integration of the pathology and radiographic appearance with the biologic heterogeneity associated with these tumors. Balancing surgery, radiation and chemotherapy to optimize disease control while limiting treatment-related morbidity is of critical importance in this susceptible population and is the focus of this review.
Zacharoulis
Stergios
S
Pediatric Oncology/Neural Tumor, Children's Hospital Los Angeles, 4650 Sunset Boulevard, #99, Los Angeles, CA 90027, USA. szacharoulis@CHLA.vsc.edu
Kieran
Mark W
MW
D001932:Brain Neoplasms / Q000473:pathology / Q000628:therapy*; D002648:Child; D003131:Combined Modality Therapy / Q000379:methods; D004358:Drug Therapy / Q000379:methods; D005910:Glioma / Q000473:pathology / Q000628:therapy*; D006801:Humans; D011878:Radiotherapy / Q000379:methods; D013043:Specialties, Surgical / Q000379:methods; D016896:Treatment Outcome