[Human biomonitoring investigations of organochlorine compounds -- PCB, DDE, HCB, beta- and gamma-HCH, PCDD/PCDF, Dioxin-like PCB's and polybrominated biphenyl ethers].
Although PCB and PCB-containing materials are not processed for a long time, PCB is under discussion again and again caused by the pollution of indoor environments. To objectify the discussion, the dates of the PCB-biomonitoring, the organochlorine-compounds (DDE, HCB, beta-/gamma -HCH, PCDD/PCDF) and the polybrominated biphenyl ethers concerning the investigations within the project "Sentinel Health Departments" in Baden-Wurttemberg are represented. Additionally results from children from Kazakhstan (Aral-Sea area) and from teachers which are working in PCB polluted schools as well as from a long term investigated test person are reported. Blood concentrations of the following compounds decreased from 1996/97 to 2002/03: the sum of the concentration of PCB 138,153 and 180 decreased from 0.46 microg/L to 0.20 microg/L, DDE from 0.32 microg/L to 0.17 microg/, HCB from 0.20 microg/L to 0.08 microg/L, beta-HCH below the level of detection, I-TEQ NATO to 4.8 pg/g blood fat, TEQ WHO (without PCB) to 5.5 pg/g blood fat, PCB 126 to 18,8,pg/g blood fat and PCB 169 to 12.8 pg/g blood fat. The influence of breast feeding and the gender on the level of the pollution is conspicious. No local correlations were found in Baden-Wurttemberg, but they were found in comparison with the results of Kazakhstan (Aral-Sea area). The difficulty to produce time series while the analyzing pollutants are more and more decreasing, as well as the change of the calculation base of the summation of parameters like I-TEQ NATO to TEQ WHO are discussed.
Gabrio
T
T
Landesgesundheitsamt Baden-Württemberg, Stuttgart. gabrio@lga.bwl.de
Broser
S
S
Erdinger
L
L
Felder-Kennel
A
A
Fichtner
G
G
Häberle
E
E
Herrmann
T
T
Kirsch
H
H
Kouros
B
B
Link
B
B
Maisner
V
V
Mann
V
V
Päpke
O
O
Piechotowski
I
I
Rzonca
E
E
Schick
K-H
KH
Schrimpf
M
M
Schröder
S
S
Spöker-Maas
K
K
Weidner
U
U
Wuthe
J
J
Zöllner
I
I
Zöltzer
D
D
D000328:Adult; D000367:Age Factors; D001572:Benzofurans / Q000097:blood; D001713:Biphenyl Compounds / Q000097:blood*; D001822:Body Burden; D001942:Breast Feeding; D002648:Child; D002675:Child, Preschool; D002849:Chromatography, Gas; D003627:Data Interpretation, Statistical; D003633:Dichlorodiphenyl Dichloroethylene / Q000097:blood; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000097:blood*; D005260:Female; D005659:Fungicides, Industrial / Q000097:blood; D005858:Germany; D006581:Hexachlorobenzene / Q000097:blood; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000097:blood*; D007306:Insecticides / Q000097:blood; D007623:Kazakhstan; D008297:Male; D010575:Pesticides / Q000097:blood*; D011075:Polybrominated Biphenyls / Q000097:blood; D011078:Polychlorinated Biphenyls / Q000097:blood; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000097:blood; D012737:Sex Factors; D012989:Soil Pollutants / Q000097:blood
D001572:Benzofurans; D001713:Biphenyl Compounds; D004785:Environmental Pollutants; D005659:Fungicides, Industrial; D006843:Hydrocarbons, Chlorinated; D007306:Insecticides; D010575:Pesticides; D011075:Polybrominated Biphenyls; D000072317:Polychlorinated Dibenzodioxins; D012989:Soil Pollutants; D003633:Dichlorodiphenyl Dichloroethylene; D006581:Hexachlorobenzene; D011078:Polychlorinated Biphenyls