title: [Contribution of computed tomography in experimental sinus surgery].
abstract: OBJECTIVE
  To study the contribution of computed tomography (CT) to evaluate the intensity of the sinus mucosa's response to an inflammatory stimulus.
  
  
  METHODS
  Eight New-Zealand white rabbits where used. Rabbit n degrees 1 was the control. CT, macroscopic examination with analysis of secretion volumes, and histological examination were used to study the response of the sinuses to inflammation.
  
  
  RESULTS
  There was perfect match between the CT scan aspect and the quantity of secretions (kappa and Cohen's coefficient=1). The CT scan aspect well correlated with inflammatory cell infiltration (kappa and Cohen's coefficients=0.8).
  
  
  CONCLUSIONS
  The CT scan contributes usefully to the analysis of sinus contents and can be used to assess the intensity of the sinus mucosal inflammatory reaction. Consequently, the CT scan can be used not only to validate an animal model of acute or chronic sinusitis, but can also be used to evaluate medical or surgical treatments in such an animal model.
authors.affiliation: Service d'ORL et de chirurgie de la Face et du Cou, Hôpital Pasteur, 30 avenue de la voie romaine BP 69, 06002 Nice cedex 1. nicolas.guevara@wanadoo.fr
authors.forename: N
authors.initials: N
authors.lastname: Guevara
authors.forename: J
authors.initials: J
authors.lastname: Santini
authors.forename: L
authors.initials: L
authors.lastname: Castillo
mesh_terms: D000818:Animals; D010256:Paranasal Sinuses / Q000000981:diagnostic imaging* / Q000601:surgery*; D011817:Rabbits; D014057:Tomography, X-Ray Computed