[Anemia as a prognostic factor in a population hospitalized due to decompensated heart failure].
OBJECTIVE
To study the prevalence and prognostic value of anemia in a population hospitalized due to decompensated heart failure.


METHODS
From July to September, 2001, 204 patients were included in a multicenter hospital registry of heart failure (EPICA Study--Niterói). This retrospective analysis comprised 142 patients with data about hematocrit and hemoglobin levels collected on hospital admission. The mean age was 69.5+/-13.3 years, and 72 (50.7%) patients were men. Hemoglobin levels < 13.5 g/dL for men and < 12 g/dL for women were considered anemia. The relation between anemia and in-hospital mortality was assessed through univariate and multivariate analysis with logistic regression.


RESULTS
Anemia was observed in 89 (62.6%) patients, 52 (58%) men and 37 (42%) women. Mortality in anemic patients was 16.8% and, in nonanemic, it was 8% (P=0.11). In both sexes, the mortality rates in anemic and nonanemic patients were, respectively, 19.2% vs 0% (P=0.034) and 13.5% vs 12.2% (P=0.86). Through multivariate analysis, the following variables were found to be independently related to in-hospital mortality: hyponatremia [RR=7.0; 95% confidence interval (95% CI)=6.1 to 8.7; P=0.0001], anemia (RR=3.1, 95% CI=2.4 to 4.3; P=0.024), and presence of NYHA functional class IV (RR=1.9; 95% CI=1.3 to 2.6; P=0.04).


CONCLUSIONS
In the population studied with decompensated heart failure, the presence of anemia was an independent marker of in-hospital mortality. Mortality in the group with anemia was significantly high among men.
Sales
Ana Luíza F
AL
Universidade Federal Fluminense, Niterói, Rio de Janeiro, RJ.
Villacorta
Humberto
H
Reis
Leandro
L
Mesquita
Evandro Tinoco
ET
D000368:Aged; D000704:Analysis of Variance; D000740:Anemia / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D001938:Brazil / Q000453:epidemiology; D005260:Female; D006333:Heart Failure / Q000150:complications* / Q000401:mortality; D006760:Hospitalization; D006801:Humans; D008297:Male; D015995:Prevalence; D011379:Prognosis; D012189:Retrospective Studies