Direct electron transfer between copper-containing proteins and electrodes.
The electrochemistry of some copper-containing proteins and enzymes, viz. azurin, galactose oxidase, tyrosinase (catechol oxidase), and the "blue" multicopper oxidases (ascorbate oxidase, bilirubin oxidase, ceruloplasmin, laccase) is reviewed and discussed in conjunction with their basic biochemical and structural characteristics. It is shown that long-range electron transfer between these enzymes and electrodes can be established, and the mechanistic schemes of the DET processes are proposed.
Shleev
Sergey
S
Department of Analytical Chemistry, Lund University, P.O. Box 124, SE-221 00 Lund, Sweden.
Tkac
Jan
J
Christenson
Andreas
A
Ruzgas
Tautgirdas
T
Yaropolov
Alexander I
AI
Whittaker
James W
JW
Gorton
Lo
L
D000327:Adsorption; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D004563:Electrochemistry / Q000295:instrumentation* / Q000379:methods*; D004566:Electrodes; D004579:Electron Transport; D004800:Enzymes, Immobilized / Q000737:chemistry; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry*
D020099:Coated Materials, Biocompatible; D004800:Enzymes, Immobilized; D011506:Proteins; D003300:Copper