title: [Study on optimal extraction process of Yinju sugarless granules with orthogonal design].
abstract: OBJECTIVE
  To study the extxtraction process of chlorogenic acid from Yinju sugarless granules.
  
  
  METHODS
  The optimal extraction process was selected with orthogonal design. The content of chlorogenic acid in the extract was detremined.
  
  
  RESULTS
  The content of chlorogenic acid was influenced by frequency of extraction, the quantity of water and the concentration of ethanol.
  
  
  CONCLUSIONS
  The optimal extraction process is extraction 3 times with 10 times water and with 70% ethanol.
authors.affiliation: The First People' s Hosptil of Guangzhou, Guangzhou 510180.
authors.forename: Weihui
authors.initials: W
authors.lastname: Su
authors.forename: Mushui
authors.initials: M
authors.lastname: Chen
authors.forename: Jiemei
authors.initials: J
authors.lastname: Ren
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D002726:Chlorogenic Acid / Q000032:analysis / Q000302:isolation & purification*; D004304:Dosage Forms; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D000431:Ethanol; D035264:Flowers / Q000737:chemistry; D006358:Hot Temperature; D010946:Plants, Medicinal / Q000737:chemistry*; D011786:Quality Control; D013056:Spectrophotometry, Ultraviolet; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D004304:Dosage Forms; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D002726:Chlorogenic Acid; D000431:Ethanol