Prevalence and sexual risk of hepatitis C virus infection when human immunodeficiency virus was acquired through sexual intercourse among patients of the Lyon University Hospitals, France, 1992-2002.
To report the prevalence and the risk factors for hepatitis C virus (HCV) infection in a hospital cohort of 2691 sexually human immunodeficiency virus (HIV)-infected patients. The patients were enrolled in the Lyon section of the French Hospital Database on HIV between 1992 and 2002. Baseline characteristics were analysed. The detection of HCV-antibodies (Ab) was used for diagnosis. The HCV-Ab prevalence rate was 5.7 and 12.89% for individuals infected by HIV after homosexual intercourse or heterosexual intercourse, respectively. HCV-Ab was three times more frequently found among patients infected with HIV after heterosexual intercourse compared with patients infected with HIV after homosexual intercourse (adjusted OR: 3.2, 95% CI: 2.28-4.62, multiple logistic regression). The risk of HCV infection among HIV-infected individuals differed according to sexual behaviour. The determinants associated with HCV transmission through the sexual route needs to be explored further.
D'Oliveira
A
A
Laboratory of Epidemiology and Public Health, INSERM U271, 69373 Lyon, France.
Voirin
N
N
Allard
R
R
Peyramond
D
D
Chidiac
C
C
Touraine
J-L
JL
Fabry
J
J
Trepo
C
C
Vanhems
P
P
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D015331:Cohort Studies; D003075:Coitus; D016001:Confidence Intervals; D005260:Female; D005602:France / Q000453:epidemiology; D015658:HIV Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission*; D019698:Hepatitis C, Chronic / Q000453:epidemiology* / Q000635:transmission*; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D011336:Probability; D012189:Retrospective Studies; D012309:Risk-Taking; D012720:Severity of Illness Index; D017678:Sex Distribution; D012749:Sexually Transmitted Diseases / Q000175:diagnosis / Q000453:epidemiology*; D015996:Survival Rate