Superovulation in mice in relation to their age.
Superovulation in mice is most likely to be successful if they are treated at the age of 20-32 days. Both the number of ovulations and the quality of the embryos are significantly better in comparison with superovulated older mice (32-60 days). In this investigation the production of normally developed embryos in young mice of 20-32 days old was 28.7 per superovulated animal and 11.3 or 14.0 in the groups of older mice respectively (32-46 days and 46-60 days).
Hoogenkamp
H
H
Lewing
P
P
D000367:Age Factors; D000375:Aging / Q000502:physiology; D000818:Animals; D006063:Chorionic Gonadotropin / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D051379:Mice / Q000502:physiology*; D010062:Ovulation Induction / Q000379:methods / Q000662:veterinary*; D012741:Sexual Maturation; D013480:Superovulation / Q000187:drug effects / Q000502:physiology*; D013997:Time Factors
D006063:Chorionic Gonadotropin