[Report on 16 rare species of human chromosomal].
By examining the lymphocytic chromosomes of peripheral blood from patients with amenorrhea, spontaneous abortion and stillbirth history, .the 16 rare species of human chromosomal abnormal karyotypes were discovered. They were 46,XY,t(6;11)(q25;p15);46,XY,inv(3)(p25;q29);46,XY,t(7;18)(q10;p10);46,X,t(X;13)(q24;q14);46,XY,t(4;7)(q33;q22);46,XY,t(8;15)(q24;q15);46,XY,t(2;17)(q33;q25);46,XX,t(4;7)(q34;q11);46,XX,t(1;3)(p36;p23);46,XX,t(4;6)(q35;p11);46,X,inv(X)(q22;q28);46,XX,t(7;10)(p11;q26);46,XX,t(3;6)(p21;q23);46,XX,t(8;16)(p21;p13);46,XX,t(8;9)(q21;q34);46,XY,t(17;22)(q21;q11). Their clinical situation were described. Discussion on the relationship between the chromosomal aberrations and phenotype effect indicates the importance of chromosome karyotyping in patients with abnormal reproductive history.
Han
Wei-Tian
WT
Liaoning Open Laboratory of Reproductive Medicine, Shenyang 110031,China. hwtzzf@sohu.com
Wang
Ge
G
Jiang
Miao
M
Zhang
Zhi-Fen
ZF
Liu
Guang-Xing
GX
Wang
Chao-Xiang
CX
Bian
Chao-Ying
CY
Yu
Ping
P
D000026:Abortion, Habitual; D000293:Adolescent; D000328:Adult; D000568:Amenorrhea; D002869:Chromosome Aberrations; D025063:Chromosome Disorders / Q000235:genetics* / Q000473:pathology; D007446:Chromosome Inversion; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D011247:Pregnancy; D050497:Stillbirth; D014178:Translocation, Genetic