title: Bioavailability of calcium from milk-based formulas and fruit juices containing milk and cereals estimated by in vitro methods (solubility, dialyzability, and uptake and transport by caco-2 cells).
abstract: An adequate calcium intake during the first years of life is needed for normal growth and development and to prevent rickets. The bioavailability of calcium from infant foods (milk-based formulas and fruit juices containing milk and cereals, FMC), the dietary sources of calcium in these stages of life, has been estimated on the basis of simulated gastrointestinal digestion and calcium solubility and dialyzability values and on the efficiency of transport and uptake by Caco-2 cells. The ranking of samples according to calcium bioavailability depends on the use of solubility or dialyzability as criterion. On the basis of the former, the highest value corresponded to adapted formulas and the lowest to fruit juices. However, when using percentage dialysis, the highest value corresponded to fruit juices and the lowest to follow-up formulas. The highest percentages of transport efficiency and uptake by Caco-2 cells corresponded to calcium from the analyzed fruit juices, followed by toddler, follow-up, and adapted formulas.
authors.affiliation: Nutrition and Food Chemistry, Faculty of Pharmacy, University of Valencia, Avenida Vicente Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain.
authors.forename: Sara
authors.initials: S
authors.lastname: Perales
authors.forename: Reyes
authors.initials: R
authors.lastname: Barberá
authors.forename: M Jesús
authors.initials: MJ
authors.lastname: Lagarda
authors.forename: Rosaura
authors.initials: R
authors.lastname: Farré
mesh_terms: D000818:Animals; D001628:Beverages / Q000032:analysis*; D001682:Biological Availability; D001692:Biological Transport; D018938:Caco-2 Cells; D002118:Calcium / Q000737:chemistry / Q000493:pharmacokinetics*; D003956:Dialysis; D002523:Edible Grain / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry*; D006801:Humans; D041943:Infant Formula / Q000737:chemistry*; D008892:Milk / Q000737:chemistry*; D008954:Models, Biological; D012995:Solubility
chemical_list: D002118:Calcium