title: [Three advanced gastric cancer patients successfully treated by combination therapy of docetaxel and TS-1].
abstract: We have experienced three gastric carcinoma cases successfully treated by the combination therapy of docetaxel and TS-1. Case 1: 66-year-old male with advanced gastric cancer invading the pancreas with metastasis to the liver and left neck lymph nodes. Case 2: 50-year-old female with scirrhous gastric carcinoma causing huge amount of malignant ascites. Case 3: 59-year-old male with recurrent gastric cancer of the remnant stomach presenting with obstruction and vessel involvement. Primary and metastatic diseases of these patients were remarkably improved with the combination therapy, indicating that the combination therapy of docetaxel and TS-1 can be a new therapeutic tool for advanced and recurrent gastric cancer patients.
authors.affiliation: Dept of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University.
authors.forename: Takahisa
authors.initials: T
authors.lastname: Suzuki
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yoshida
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Tanabe
authors.forename: Jun
authors.initials: J
authors.lastname: Hihara
authors.forename: Koji
authors.initials: K
authors.lastname: Ohta
authors.forename: Youichi
authors.initials: Y
authors.lastname: Hamai
authors.forename: Junya
authors.initials: J
authors.lastname: Taomoto
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Toge
mesh_terms: D002293:Adenocarcinoma, Scirrhous / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D000077143:Docetaxel; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000008:administration & dosage; D011725:Pyridines / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D043823:Taxoids / Q000008:administration & dosage; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; D011725:Pyridines; D043823:Taxoids; C079198:S 1 (combination); D005641:Tegafur; D000077143:Docetaxel; D010094:Oxonic Acid