title: Haloxylines A and B, antifungal and cholinesterase inhibiting piperidine alkaloids from Haloxylon salicornicum.
abstract: Haloxylines A (1) and B (2), new piperidine alkaloids, have been isolated from the chloroform soluble fraction of Haloxylon salicornicum and their structures elucidated by spectroscopic techniques including 2D-NMR. Both the compounds displayed antifungal and cholinesterase enzymes inhibitory potentials.
authors.affiliation: Pharmaceutical Research Center, PCSIR Laboratories Karachi Complex, Karachi-75280, Pakistan.
authors.forename: Sadia
authors.initials: S
authors.lastname: Ferheen
authors.forename: Ejaz
authors.initials: E
authors.lastname: Ahmed
authors.forename: Nighat
authors.initials: N
authors.lastname: Afza
authors.forename: Abdul
authors.initials: A
authors.lastname: Malik
authors.forename: Muhammad Raza
authors.initials: MR
authors.lastname: Shah
authors.forename: Sarfraz Ahmad
authors.initials: SA
authors.lastname: Nawaz
authors.forename: Muhammad Iqbal
authors.initials: MI
authors.lastname: Choudhary
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism; D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D027703:Amaranthaceae; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects; D002800:Cholinesterase Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010880:Piperidines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018514:Plant Structures
chemical_list: D000470:Alkaloids; D000935:Antifungal Agents; D002800:Cholinesterase Inhibitors; D010880:Piperidines; D010936:Plant Extracts; D000110:Acetylcholinesterase