title: Effective use of fibrin glue for acute aortic dissection.
abstract: The use of gelatin-resorcine-formalin (GRF) glue for reconstruction of the vascular wall in the context of acute aortic dissection has become more common. However, anecdotal evidence suggests that use of the GRF glue results in higher rates of postoperative redissection. We describe an alternative method of reinforcing the dissected aorta with fibrin glue that may avoid this complication. A fabric sheet is presoaked in fibrinogen solution and then placed within the false lumen. Thrombin solution is then applied to the fabric sheet. That results in obliteration of the false lumen and effective reinforcement of the dissected wall.
authors.affiliation: Department of Cardiovascular Surgery, Iwate Medical University Memorial Heart Center, Iwate Medical University, Morioka, Japan. t_nakajima@imu.ncvc.go.jp
authors.forename: Takayuki
authors.initials: T
authors.lastname: Nakajima
authors.forename: Kohei
authors.initials: K
authors.lastname: Kawazoe
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Izumoto
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Kataoka
authors.forename: Toshinobu
authors.initials: T
authors.lastname: Kazui
mesh_terms: D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D002315:Cardiopulmonary Bypass; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D005340:Fibrinogen / Q000627:therapeutic use; D005780:Gelatin; D006801:Humans; D007036:Hypothermia, Induced; D019651:Plastic Surgery Procedures / Q000379:methods; D013917:Thrombin / Q000627:therapeutic use
chemical_list: D015718:Fibrin Tissue Adhesive; D005780:Gelatin; D005340:Fibrinogen; D013917:Thrombin