Enantioselective ring-opening reaction of meso-epoxides with ArSeH catalyzed by heterometallic Ti-Ga-Salen system.
The first example of enantioselective ring-opening reaction of meso-epoxides with aryl selenols to give optically active beta-arylseleno alcohol in up to 97% ee was realized, using a chiral Ti-Ga-Salen heterometallic catalyst. A strong synergistic effect of different Lewis acids in the system was exhibited in the catalytic process.
Yang
Minghua
M
State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, China.
Zhu
Chengjian
C
Yuan
Fang
F
Huang
Yijun
Y
Pan
Yi
Y