[Age and gender: confounders for axis I disorders as risk factors for suicide].
OBJECTIVE
Aim of the study was to identify and estimate psychiatric axis I disorders as risk factors for suicide in different age groups using a psychological autopsy study with case-control design. 163 suicides and 396 population-based control persons were assessed with a standardized semi-structured interview including SCID-I (for DSM-IV).


RESULTS
Logistic regression analyses revealed significantly elevated odds ratios for alcohol-related disorders in men aged 31 to 45, 46 to 60, and 61 to 75 years (OR = 9.0, OR = 7.5, and OR = 10.7, respectively) and for Major Depression, single episode, in men and women aged 61 to 75 years (OR = 42.7 and OR = 15.9). In males aged 31 to 45 years polysubstance-related disorders (OR = 9.5) and in females aged 61 to 75 years cognitive and mental disorders due to a general medical condition (OR = 12.2) were significantly and independently associated with suicide.


CONCLUSIONS
Alcohol-related disorders and Major Depression differently contribute to male and female suicide risk in special age groups. These findings imply differentiated prevention strategies.
Schneider
Barbara
B
Zentrum der Psychiatrie, Klinik für Psychiatrie und Psychotherapie, Johann-Wolfgang-Goethe-Universität, Frankfurt/Main. b.schneider@em.uni-frankfurt.de
Bartusch
Bernadette
B
Schnabel
Axel
A
Fritze
Jürgen
J
D000328:Adult; D000367:Age Factors; D000368:Aged; D000437:Alcoholism / Q000175:diagnosis / Q000401:mortality / Q000523:psychology; D002423:Cause of Death; D003704:Dementia / Q000175:diagnosis / Q000401:mortality / Q000523:psychology; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000401:mortality / Q000523:psychology; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D005858:Germany; D006801:Humans; D007406:Interview, Psychological; D016015:Logistic Models; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis* / Q000401:mortality / Q000523:psychology; D008875:Middle Aged; D016017:Odds Ratio; D010552:Personality Assessment / Q000706:statistics & numerical data; D011594:Psychometrics; D015203:Reproducibility of Results; D018570:Risk Assessment; D012737:Sex Factors; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000401:mortality / Q000523:psychology; D013405:Suicide / Q000523:psychology / Q000706:statistics & numerical data; D000092864:Suicide Prevention