title: Quantitative cartilage volume measurement using MRI: comparison of different evaluation techniques.
abstract: This study was aimed to investigate the accuracy and time saving of MRI Argus application in the assessment of cartilage volume in osteoarthritic knees. Twelve knees of patients suffering from osteoarthritis were scanned with a 1.5 T MRI using a 3D gradient echo sequence with selective water excitation. Cartilage volume of the tibial and patellar compartment was determined with a validated multiprocessing computer system (Octane Duo, Silicon Graphics, Mountain View, Calif., USA). The calculated cartilage volumes were compared to the results acquired by the Argus (Siemens Inc., Erlangen, Germany) application software using the MRI data sets. Compared to the multiprocessing computer system a time saving of at least 30 min for cartilage volume determination was achieved. The mean differences of Argus versus the multiprocessing computer system were 4.26+/-0.84 and 7.80+/-0.87% for the medial and lateral tibial plateau and 5.94+/-0.59% for the patella (no statistical significant difference; P>0.05). The applied Argus software can be used for fast and accurate determination of cartilage volume in the knee joint.
authors.affiliation: Institute for Diagnostic and Interventional Radiology, J. W. Goethe-University Frankfurt/Main, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany. adel.maataoui@gmx.de
authors.forename: Adel
authors.initials: A
authors.lastname: Maataoui
authors.forename: Heiko
authors.initials: H
authors.lastname: Graichen
authors.forename: Nasreddin D
authors.initials: ND
authors.lastname: Abolmaali
authors.forename: Mohammad F
authors.initials: MF
authors.lastname: Khan
authors.forename: Jessen
authors.initials: J
authors.lastname: Gurung
authors.forename: Ralf
authors.initials: R
authors.lastname: Straub
authors.forename: Jun
authors.initials: J
authors.lastname: Qian
authors.forename: Stefan
authors.initials: S
authors.lastname: Hinterwimmer
authors.forename: Hanns
authors.initials: H
authors.lastname: Ackermann
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Vogl
mesh_terms: D000368:Aged; D000465:Algorithms; D002358:Cartilage, Articular / Q000473:pathology*; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D020370:Osteoarthritis, Knee / Q000473:pathology*; D012984:Software