title: Psoriasiform contact dermatitis due to propolis in a beekeeper.
abstract: BACKGROUND
  More than 250 cases of allergic contact dermatitis due to propolis have been described. A few of these occurred in beekeepers.
  
  
  OBJECTIVE
  To describe a case of psoriasiform dermatitis caused by propolis in a beekeeper who thought that his lesions were related to honeybee stings.
  
  
  METHODS
  A 45-year-old beekeeper experienced hand dermatitis for the past 5 years. He believed that the lesions occurred and worsened when he was stung by honeybees. He was prescribed topical corticosteroids several times, but because he was stung frequently, the drugs never helped control the lesions. In the past few years, he frequently had contact with propolis during honey collection, but he denied the role of propolis because he was wearing gloves while handling the beehives. For diagnostic evaluation, skin biopsy, skin prick tests (SPTs), identification of specific IgE antibodies, and atopic patch tests were performed.
  
  
  RESULTS
  Skin biopsy showed psoriasiform contact dermatitis. Results of SPTs to honeybee and serum specific IgE for Apis mellifera remained negative. Results of the atopic patch test performed using A mellifera SPT material were also negative in the first 20 minutes and on the second and third days. However, propolis showed a positive erythematopapular reaction on day 2. The patient never again worked as a beekeeper, and neither did he, as far as he knew, use any medical or cosmetic products that contained propolis. His hand lesions improved almost completely.
  
  
  CONCLUSIONS
  Dermatitis due to propolis should never be disregarded in beekeepers, and every effort should be put forth to make a correct diagnosis and to convince the patients of the cause.
authors.affiliation: Department of Internal Medicine, Ege University Medical School, Bornova-Izmir, Turkey. ogulbahar@yahoo.com
authors.forename: Okan
authors.initials: O
authors.lastname: Gulbahar
authors.forename: Gunseli
authors.initials: G
authors.lastname: Ozturk
authors.forename: Nihat
authors.initials: N
authors.lastname: Erdem
authors.forename: Ali Can
authors.initials: AC
authors.lastname: Kazandi
authors.forename: Ali
authors.initials: A
authors.lastname: Kokuludag
mesh_terms: D001706:Biopsy; D017449:Dermatitis, Allergic Contact / Q000276:immunology*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D011429:Propolis / Q000276:immunology*; D012882:Skin Tests
chemical_list: D007073:Immunoglobulin E; D011429:Propolis