title: Laccase expression in murine pulmonary Cryptococcus neoformans infection.
abstract: Cryptococcus neoformans laccase expression during murine infection was investigated in lung tissue by immunohistochemistry and immunogold electron microscopy. Laccase was detected in the fungal cell cytoplasm, cell wall, and capsule in vivo. The amount of laccase found in different sites varied as a function of the time of infection.
authors.affiliation: Division of Infectious Disease, Albert Einstein College of Medicine, 1300 Morris Park Ave., Golding 701, Bronx, NY 10461, USA.
authors.forename: Javier
authors.initials: J
authors.lastname: Garcia-Rivera
authors.forename: Stephanie C
authors.initials: SC
authors.lastname: Tucker
authors.forename: Marta
authors.initials: M
authors.lastname: Feldmesser
authors.forename: Peter R
authors.initials: PR
authors.lastname: Williamson
authors.forename: Arturo
authors.initials: A
authors.lastname: Casadevall
mesh_terms: D000818:Animals; D003453:Cryptococcosis / Q000382:microbiology*; D003455:Cryptococcus neoformans / Q000201:enzymology* / Q000472:pathogenicity / Q000648:ultrastructure*; D007150:Immunohistochemistry; D042845:Laccase / Q000378:metabolism*; D008168:Lung / Q000382:microbiology; D008172:Lung Diseases, Fungal / Q000382:microbiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008854:Microscopy, Electron; D014774:Virulence
chemical_list: D042845:Laccase