title: Recognition in action: flipping pyrimidine dimers.
abstract: DNA bases are normally sheltered within a double helix, but enzymes that modify and repair DNA gain access by flipping individual bases out of the double helix.
authors.affiliation: Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA. goodsell@scripps.edu
authors.forename: David S
authors.initials: DS
authors.lastname: Goodsell
mesh_terms: D004247:DNA / Q000737:chemistry / Q000378:metabolism; D004249:DNA Damage; D011088:DNA Ligases / Q000378:metabolism*; D004260:DNA Repair / Q000502:physiology*; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D011740:Pyrimidine Dimers / Q000737:chemistry / Q000378:metabolism / Q000528:radiation effects; D014466:Ultraviolet Rays / Q000009:adverse effects
chemical_list: D011740:Pyrimidine Dimers; D004247:DNA; D011088:DNA Ligases