title: Highly enantioselective conjugate addition of nitromethane to chalcones using bifunctional cinchona organocatalysts.
abstract: Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.
authors.affiliation: Institute of Biomolecular Chemistry, Chemical Research Center of Hungarian Academy of Sciences, Budapest.
authors.forename: Benedek
authors.initials: B
authors.lastname: Vakulya
authors.forename: Szilárd
authors.initials: S
authors.lastname: Varga
authors.forename: Antal
authors.initials: A
authors.lastname: Csámpai
authors.forename: Tibor
authors.initials: T
authors.lastname: Soós
mesh_terms: D002384:Catalysis; D047188:Chalcones / Q000737:chemistry*; D002929:Cinchona / Q000737:chemistry; D002930:Cinchona Alkaloids / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D009595:Nitroparaffins / Q000737:chemistry*; D013237:Stereoisomerism; D013890:Thiourea / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D047188:Chalcones; D002930:Cinchona Alkaloids; D009595:Nitroparaffins; D013890:Thiourea; D008697:Methane; C008640:nitromethane