title: Synthesis of polycyclic aromatics and heteroaromatics via electrophilic cyclization.
abstract: [reaction: see text] A variety of substituted polycyclic aromatics are readily prepared in good to excellent yields under very mild reaction conditions by the reaction of 2-(1-alkynyl)biphenyls with ICl, I(2), NBS, and p-O(2)NC(6)H(4)SCl. This methodology readily accommodates various functional groups and has been successfully extended to systems containing a variety of polycyclic and heterocyclic rings.
authors.affiliation: Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
authors.forename: Tuanli
authors.initials: T
authors.lastname: Yao
authors.forename: Marino A
authors.initials: MA
authors.lastname: Campo
authors.forename: Richard C
authors.initials: RC
authors.lastname: Larock
mesh_terms: D002384:Catalysis; D003500:Cyclization; D006576:Heterocyclic Compounds, 4 or More Rings / Q000032:analysis / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis / Q000138:chemical synthesis*
chemical_list: D006576:Heterocyclic Compounds, 4 or More Rings; D007202:Indicators and Reagents; D011084:Polycyclic Aromatic Hydrocarbons; D010165:Palladium