Recognition in action: flipping pyrimidine dimers.
DNA bases are normally sheltered within a double helix, but enzymes that modify and repair DNA gain access by flipping individual bases out of the double helix.
Goodsell
David S
DS
Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA. goodsell@scripps.edu
D004247:DNA / Q000737:chemistry / Q000378:metabolism; D004249:DNA Damage; D011088:DNA Ligases / Q000378:metabolism*; D004260:DNA Repair / Q000502:physiology*; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D011740:Pyrimidine Dimers / Q000737:chemistry / Q000378:metabolism / Q000528:radiation effects; D014466:Ultraviolet Rays / Q000009:adverse effects
D011740:Pyrimidine Dimers; D004247:DNA; D011088:DNA Ligases