[Study on optimal extraction process of Yinju sugarless granules with orthogonal design].
OBJECTIVE
To study the extxtraction process of chlorogenic acid from Yinju sugarless granules.


METHODS
The optimal extraction process was selected with orthogonal design. The content of chlorogenic acid in the extract was detremined.


RESULTS
The content of chlorogenic acid was influenced by frequency of extraction, the quantity of water and the concentration of ethanol.


CONCLUSIONS
The optimal extraction process is extraction 3 times with 10 times water and with 70% ethanol.
Su
Weihui
W
The First People' s Hosptil of Guangzhou, Guangzhou 510180.
Chen
Mushui
M
Ren
Jiemei
J
D019659:Asteraceae / Q000737:chemistry*; D002726:Chlorogenic Acid / Q000032:analysis / Q000302:isolation & purification*; D004304:Dosage Forms; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D000431:Ethanol; D035264:Flowers / Q000737:chemistry; D006358:Hot Temperature; D010946:Plants, Medicinal / Q000737:chemistry*; D011786:Quality Control; D013056:Spectrophotometry, Ultraviolet; D013678:Technology, Pharmaceutical / Q000379:methods*
D004304:Dosage Forms; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D002726:Chlorogenic Acid; D000431:Ethanol