title: Long-term follow-up of continent urinary diversion after pelvic exenteration for gynecologic malignancies.
abstract: OBJECTIVE
  The objective of this retrospective study was to analyze the long-term outcome of patients undergoing a continent urinary diversion (UD) at the time of pelvic exenteration (PE).
  
  
  METHODS
  Between February 1993 and January 2001, 60 PE for gynecologic malignancies and requiring a UD were performed. Patient's preference, type of UD planned, type of UD performed, and late urinary morbidity (after day 90) were analyzed.
  
  
  RESULTS
  Eighty-two percent of the entire group (49/60) matched preoperatively criteria to have a continent UD and 41 continent UD were eventually performed (87%). Postoperative mortality in patients with a continent UD was 4.9% (2/41) and wasn't related to urinary complications. After a 20-month median follow-up, 18 patients (46%) with a continent UD developed late complications directly UD-related. These complications were: (a) major in 28% (5/18) requiring re-operation in 3 cases or endoscopic treatment in 2 cases; (b) minor in 72% (13/18) constantly medically treated. Chronic diarrhea was more frequent in patient who had small bowel or left colon resection (P < 0.05) and urine leakage was more frequent in patient with higher BMI (P < 0.05). At last follow-up, no patient had stopped self-catheterizations or asked for undiversion.
  
  
  CONCLUSIONS
  In our experience, continent UD at the time of PE despite high acceptability and feasibility rate, appeared to be strongly related to specific late complications, uncommon with ileal conduit. However, these complications remained more frequently minor and could be treated safely and conservatively.
authors.affiliation: Assistance publique-Hôpitaux de Marseille, Hôpital Salvator, Urology Department, Marseille, France; Université de la Méditerranée, Faculté de Médecine, Marseille, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Karsenty
authors.forename: Vincent
authors.initials: V
authors.lastname: Moutardier
authors.forename: Bernard
authors.initials: B
authors.lastname: Lelong
authors.forename: Jérome
authors.initials: J
authors.lastname: Guiramand
authors.forename: Gilles
authors.initials: G
authors.lastname: Houvenaeghel
authors.forename: Jean Robert
authors.initials: JR
authors.lastname: Delpero
authors.forename: Franck
authors.initials: F
authors.lastname: Bladou
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D005833:Genital Neoplasms, Female / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D010385:Pelvic Exenteration / Q000009:adverse effects*; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome; D014547:Urinary Diversion / Q000009:adverse effects*; D014555:Urination Disorders / Q000209:etiology