title: [Cardiovascular disease in Chinese chronic renal insufficiency patients-epidemiology survey].
abstract: OBJECTIVE
  Cardiovascular (CV) disease (CVD) is the single most important cause of death among Chinese dialysis patients, accounting for 51% of overall mortality. The study was performed to investigate the prevalence and the spectrum of CVD in Chinese chronic kidney disease (CKD) patients.
  
  
  METHODS
  The multicenter Chinese cohort study examined 1239 CKD patients from 7 main medical centers (distributed in 5 regions of China) who were hospitalized between 2002 and 2003.
  
  
  RESULTS
  (1) The most prevalent pathological form of CVD was left ventricular (LV) hypertrophy (LVH), accounting for 58.5% of total patients. The prevalence of coronary artery disease (CAD), congestive heart failure (CHF), and cerebrovascular accidents (CVA) was 16.5%, 27.7% and 5.6%, separately. (2) The cohort with minor renal dysfunction (stage 2-3) had higher prevalence of CAD (5.9%) and CVA (1.0%) compared with general population in the same regions. Up to 41.2% of minor CKD patients were complicated with LVH, and 13.8% of them had clinical evidence of CHF. The prevalence of CAD, LVH and CHF increased as glomerular filtration decline. (3) The prevalence of CAD (20.0%) was much lower and the prevalence of CVA (5.4%) was higher in Chinese dialysis patients than that in American dialysis population. There was significant geographical variations in CAD prevalence, but it was not different between genders.
  
  
  CONCLUSIONS
  The CV risk is significantly increased in patients with CKD. Even minor CKD has a major impact on the CV risk. The prevalence of CAD in Chinese dialysis patients is markedly lower than that in American dialysis population.
authors.affiliation: Department of Nephrology, Nanfang Hospital, Guangzhou 510515, China.
authors.forename: Fan-Fan
authors.initials: FF
authors.lastname: Hou
authors.forename: Zhi-Gang
authors.initials: ZG
authors.lastname: Ma
authors.forename: Chang-Lin
authors.initials: CL
authors.lastname: Mei
authors.forename: Shu
authors.initials: S
authors.lastname: Rong
authors.forename: Song-Min
authors.initials: SM
authors.lastname: Huang
authors.forename: Xian-Rong
authors.initials: XR
authors.lastname: Liu
authors.forename: Wei-Jie
authors.initials: WJ
authors.lastname: Yuan
authors.forename: Yun-Shan
authors.initials: YS
authors.lastname: Guo
authors.forename: Li
authors.initials: L
authors.lastname: Wang
authors.forename: Qiang
authors.initials: Q
authors.lastname: He
authors.forename: Xiu-Ling
authors.initials: XL
authors.lastname: Wang
authors.forename: Xiao-Hong
authors.initials: XH
authors.lastname: Sang
authors.forename: Xiao-Li
authors.initials: XL
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000150:complications / Q000453:epidemiology*; D002561:Cerebrovascular Disorders / Q000150:complications / Q000453:epidemiology; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D003327:Coronary Disease / Q000150:complications / Q000453:epidemiology; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000453:epidemiology; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000150:complications / Q000453:epidemiology*; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000453:epidemiology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D006435:Renal Dialysis; D012307:Risk Factors