Opening a new can of worms: a large-scale RNAi screen in planarians.
In this issue of Developmental Cell, Reddien et al. describe the first large-scale RNAi screen in freshwater planarians, classic models for regeneration studies. Their work paves the way for a detailed understanding of regeneration and tissue maintenance in these fascinating animals.
Newmark
Phillip A
PA
Department of Cell and Structural Biology, University of Illinois at Urbana-Campaign, 61801, USA.
D000818:Animals; D017238:Genes, Helminth; D005820:Genetic Testing; D008954:Models, Biological; D009154:Mutation; D010641:Phenotype; D010932:Planarians / Q000235:genetics* / Q000502:physiology*; D034622:RNA Interference; D012038:Regeneration / Q000235:genetics*