title: Self-reported visual functioning and quality of life in age-related macular degeneration.
abstract: OBJECTIVE
  To review the current literature on the impact of age-related macular degeneration on self-reported visual functioning, quality of life, and independent living.
  
  
  RESULTS
  The quantitative relationships between visual acuity, an objective clinical measure of vision, and self-reported visual functioning have been explored and described within prospective longitudinal clinical trials. When age-related macular degeneration is bilateral, the severe and irreversible loss of central vision experienced by affected persons has been shown to result in despondency, inability to care for self or others, and a state of disutility, which is equivalent to that experienced in coronary heart disease and stroke.
  
  
  CONCLUSIONS
  Quality-of-life indicators and self-reported visual functioning have gained acceptance as key outcome measure in studies designed to test therapeutic interventions and rehabilitation strategies in age-related macular degeneration. Vision loss from age-related macular degeneration engenders a profound sense of loss and the resultant handicap has been likened to that of the most severe medical conditions.
authors.affiliation: Centre for Ophthalmology and Vision Science, Queen's University, Institute for Clinical Science, Royal Group of Hospitals Trust, Belfast, UK. u.chakravarthy@qub.ac.uk
authors.forename: Usha
authors.initials: U
authors.lastname: Chakravarthy
authors.forename: Michael
authors.initials: M
authors.lastname: Stevenson
mesh_terms: D000203:Activities of Daily Living; D006801:Humans; D008268:Macular Degeneration / Q000503:physiopathology* / Q000523:psychology; D011788:Quality of Life; D012650:Self Disclosure; D014792:Visual Acuity / Q000502:physiology*