title: Subglottic tracheal stenosis as primary manifestation of a marginal zone B-cell lymphoma of the larynx.
abstract: BACKGROUND
  More than 90% of laryngeal tumors are squamous cell carcinomas. Primary hematopoetic neoplasms of the larynx are rare, being mainly extramedullary plasmocytoma and non-Hodgkin's lymphoma (NHL). These are mainly located in the supraglottic and glottic area, with only a few reported in the subglottic region.
  
  
  METHODS
  We report on a 58-year-old man, who presented at our clinic with severe dyspnea. On microlaryngoscopy, a subglottic stenosis at the level of the cricoid cartilage was found. The biopsy revealed the diagnosis of a MALT-type lymphoma (marginal zone B-cell lymphoma). The tracheostomy was followed by locoregional radiotherapy.
  
  
  CONCLUSIONS
  This is the first report of a subglottic MALT-type lymphoma causing a tracheal stenosis. The preferred treatment is locoregional radiotherapy including the draining lymph nodes.
authors.affiliation: Department of Otorhinolaryngology, Ludwig-Maximilians-University of Munich, Germany. Michaela.Andratschke@med.uni-muenchen.de
authors.forename: Michaela
authors.initials: M
authors.lastname: Andratschke
authors.forename: Klaus
authors.initials: K
authors.lastname: Stelter
authors.forename: Stephan
authors.initials: S
authors.lastname: Ihrler
authors.forename: Hjalmar
authors.initials: H
authors.lastname: Hagedorn
mesh_terms: D001706:Biopsy; D003251:Constriction, Pathologic / Q000209:etiology; D004417:Dyspnea; D005931:Glottis; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D007828:Laryngoscopy; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D014135:Tracheal Stenosis / Q000209:etiology*; D016896:Treatment Outcome