title: Human thrombin for treatment of pseudoaneurysms: comparison of bovine and human thrombin sonogram-guided injection.
abstract: OBJECTIVE
  The purpose of this research was to review our experience and determine the success rate of percutaneous sonogram-guided human thrombin injection to treat iatrogenic femoral pseudoaneurysms and compare this with the results obtained with bovine thrombin injection.
  
  
  CONCLUSIONS
  In our experience, the use of human thrombin for the treatment of iatrogenic femoral pseudoaneurysms is highly efficient (100%), the administered dose is significantly less than with bovine thrombin, and the risk for allergy is potentially lower. At our hospital, human thrombin has replaced bovine thrombin and is the first line of treatment for an iatrogenic pseudoaneurysm.
authors.affiliation: Department of Roentgenology, Hospital Universitario Virgen de la Arrixaca, Ctra. Madrid-Cartagena, El Palmar 30120, Murcia, Spain. vvs63@hotmail.com
authors.forename: Victoria
authors.initials: V
authors.lastname: Vázquez
authors.forename: Manuel
authors.initials: M
authors.lastname: Reus
authors.forename: Antonio
authors.initials: A
authors.lastname: Piñero
authors.forename: Dolores
authors.initials: D
authors.lastname: Abellán
authors.forename: Manuel
authors.initials: M
authors.lastname: Canteras
authors.forename: Mariano
authors.initials: M
authors.lastname: Espinosa de Rueda
authors.forename: Dolores
authors.initials: D
authors.lastname: Morales
authors.forename: Pascual
authors.initials: P
authors.lastname: Parrilla
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D017541:Aneurysm, False / Q000000981:diagnostic imaging / Q000188:drug therapy*; D000818:Animals; D002417:Cattle; D016009:Chi-Square Distribution; D003029:Coagulants / Q000627:therapeutic use*; D005260:Female; D005263:Femoral Artery; D006801:Humans; D007049:Iatrogenic Disease; D007267:Injections; D008297:Male; D013917:Thrombin / Q000627:therapeutic use*; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional
chemical_list: D003029:Coagulants; D013917:Thrombin