title: Imaging of photodynamically generated singlet oxygen luminescence in vivo.
abstract: We describe a novel scanning-laser system for imaging type-II photodynamically generated singlet oxygen (1O2[1delta(g)]) luminescence and demonstrate it in vivo in an intradermal tumor model in mice. We verify the strong oxygen-dependence of the signal and show that the images are near the practical resolution limit.
authors.affiliation: Department of Medical Biophysics, Ontario Cancer Institute and University of Toronto, Toronto, Ontario, Canada.
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Niedre
authors.forename: Michael S
authors.initials: MS
authors.lastname: Patterson
authors.forename: Anoja
authors.initials: A
authors.lastname: Giles
authors.forename: Brian C
authors.initials: BC
authors.lastname: Wilson
mesh_terms: D008027:Light; D008163:Luminescent Measurements; D026082:Singlet Oxygen
chemical_list: D026082:Singlet Oxygen