[Evaluation of the activity of polymorphonuclear neutrophils against Entamoeba histolytica antigens].
This paper evaluates the production of superoxide as an indicator of the activity of neutrophils from healthy individuals, stimulated with Entamoeaba histolytica membrane antigens, chemical stimulators and antigens from other parasites. The kinetic nitroblue tetrazolium reduction test was used. No significant differences were observed in the control group as to superoxide production by neutrophils primed with Entamoeba histolytica antigens or Cisticercus cellulosae, Toxoplasma gondii and Giardia lamblia antigens. These results allow us to conclude that Entamoeba histolytica membrane antigens do not induce superoxide production by neutrophils, which contradicts previous statements on suppresed activity of neutrophils after they get in contact with Entamoeaba histolytica antigens.
Manrique
Osbert Rosales
OR
Instituto de Inmunología Clínica, Ula. Mérida-Venezuela. hurdaneta84@hotmail.com
Romero
Haideé Urdaneta
HU
Barrios
Manuel Hernández
MH
Muñoz
José Francisco
JF
D000818:Animals; D000953:Antigens, Protozoan / Q000276:immunology*; D004748:Entamoeba histolytica / Q000276:immunology*; D006801:Humans; D009504:Neutrophils / Q000276:immunology* / Q000378:metabolism; D013481:Superoxides / Q000378:metabolism
D000953:Antigens, Protozoan; D013481:Superoxides