title: Quantification of myocardial function using tagged MR and cine MR images.
abstract: Magnetic Resonance Imaging (MRI) is recognized as a relevant modality for dynamically imaging the heart anatomy and function, and achieving satisfying qualitative diagnosis. Reliable methods for quantitatively analyzing cardiac motion from MR images remain, however, to be elaborated. This paper presents a novel approach for measuring myocardial deformations from tagged MRI sequences. Based on efficient pixel-based statistical non-rigid registration, it allows for automatically extracting local/global deformation parameters at the pixel and myocardial segment scales. Its performances for assessing the myocardial function are illustrated both for the normal heart and for pathologies of the ischemic and dilated cardiomyopathic type.
authors.affiliation: ARTEMIS Project Unit, GET/INT, Evry, France.
authors.forename: Caroline
authors.initials: C
authors.lastname: Petitjean
authors.forename: Nicolas
authors.initials: N
authors.lastname: Rougon
authors.forename: Philippe
authors.initials: P
authors.lastname: Cluzel
authors.forename: Françoise
authors.initials: F
authors.lastname: Prêteux
authors.forename: Philippe
authors.initials: P
authors.lastname: Grenier
mesh_terms: D000328:Adult; D000465:Algorithms; D002311:Cardiomyopathy, Dilated / Q000503:physiopathology; D005260:Female; D006321:Heart / Q000502:physiology* / Q000503:physiopathology; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology; D017202:Myocardial Ischemia / Q000503:physiopathology; D015203:Reproducibility of Results