title: Case report: painful peripheral neuropathy following treatment with docetaxel for breast cancer.
abstract: Peripheral neuropathy is a common side effect of many chemotherapy agents. As many as 60% of patients receiving taxane therapy report symptoms such as numbness, tingling, burning, pain, and, in severe cases, weakness in a stocking and glove pattern. These symptoms are associated with problems in physical mobility and decreased quality of life, yet few articles in the literature discuss collaborative interdisciplinary assessment and treatment of this population. This article describes the care of a patient with diabetes and docetaxel-induced, painful peripheral neuropathy by a multidisciplinary team of nurses, physicians, and physical therapists. Because nurses are often the first clinicians to recognize symptoms of chemotherapy-induced peripheral neuropathy, they provide the essential coordination of care by appropriate medical and rehabilitative services. This case also raises important questions about the relationship between diabetes mellitus and persistent, painful peripheral neuropathy.
authors.affiliation: medwards@itsa.ucsf.edu
authors.forename: Meredith A
authors.initials: MA
authors.lastname: Wampler
authors.forename: Deborah
authors.initials: D
authors.lastname: Hamolsky
authors.forename: Kate
authors.initials: K
authors.lastname: Hamel
authors.forename: Michelle
authors.initials: M
authors.lastname: Melisko
authors.forename: Kimberly S
authors.initials: KS
authors.lastname: Topp
mesh_terms: D000203:Activities of Daily Living; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D018450:Disease Progression; D000077143:Docetaxel; D005081:Exercise Therapy; D005260:Female; D018737:Hand Strength; D006801:Humans; D008875:Middle Aged; D024802:Nurse's Role; D009859:Oncology Nursing / Q000458:organization & administration; D010146:Pain / Q000139:chemically induced / Q000175:diagnosis; D059408:Pain Management; D010147:Pain Measurement; D010348:Patient Care Team / Q000458:organization & administration; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D011788:Quality of Life; D012720:Severity of Illness Index; D043823:Taxoids / Q000009:adverse effects*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D043823:Taxoids; D000077143:Docetaxel