title: Kearns-Sayre syndrome associated with trifascicular block and QT prolongation.
abstract: Patients suffering from Kearns-Sayre syndrome (KSS) often develop conduction defects that may lead to syncope or sudden cardiac death. The association of conduction abnormalities with prolonged QT interval in these patients is very rare. We describe a patient with KSS and diabetes mellitus who suffered a torsades de pointes-induced syncopal attack, in the presence of trifascicular block and QT prolongation (QTc: 574 ms). The patient was successfully treated with permanent pacing. This case highlights that torsades de pointes represents a potential mechanism of syncope or sudden cardiac death in patients with KSS.
authors.forename: Pavlos
authors.initials: P
authors.lastname: Karanikis
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Korantzopoulos
authors.forename: Evaggelos
authors.initials: E
authors.lastname: Kountouris
authors.forename: Vasiliki
authors.initials: V
authors.lastname: Dimitroula
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Patsouras
authors.forename: Eugenia
authors.initials: E
authors.lastname: Pappa
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Siogas
mesh_terms: D002037:Bundle-Branch Block / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D002304:Cardiac Pacing, Artificial; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D007625:Kearns-Sayre Syndrome / Q000175:diagnosis / Q000503:physiopathology*; D008133:Long QT Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008875:Middle Aged