title: Preparation of carboxymethyl chitosan in aqueous solution under microwave irradiation.
abstract: Carboxymethyl chitosan was prepared by reacting chitosan with chloroacetic acid in water under microwave irradiation. The effect of the reaction conditions was investigated and optimal conditions were identified. The influence of mass ratio of chloroacetic acid to chitosan, microwave power and pH on the degree of substitution or intrinsic viscosity were further studied. The degree of substitution of the carboxymethyl chitosan synthesized exceeded 0.85.
authors.affiliation: College of Chemistry, South China University of Technology, Guangzhou 510640, China. chhcge@scut.edu.cn
authors.forename: Hua-Cai
authors.initials: HC
authors.lastname: Ge
authors.forename: Deng-Ke
authors.initials: DK
authors.lastname: Luo
mesh_terms: D000085:Acetates / Q000737:chemistry; D048271:Chitosan / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry* / Q000528:radiation effects; D006863:Hydrogen-Ion Concentration; D008872:Microwaves; D012996:Solutions; D017550:Spectroscopy, Fourier Transform Infrared; D014867:Water / Q000737:chemistry
chemical_list: D000085:Acetates; C504164:O-carboxymethylchitosan; D012996:Solutions; D014867:Water; C006972:chloroacetic acid; D048271:Chitosan