Different manifestations of malignant melanoma in the breast: a report of 12 cases and a review of the literature.
BACKGROUND
The breast is associated with a large number of diseases. Besides being the host of many benign and malignant tumors, breast skin and parenchyma are also metastatic sites for various tumors such as leukemia, lung cancer and melanoma.


METHODS
Malign melanoma has different manifestations in the breast. All these manifestations are important not only as initial presentations of the disease, but also as indicators of the progression period of the disease.


RESULTS
This study reports on 12 cases of cutaneous malignant melanoma in breast skin and tissue. Nine of these cases are primary cutaneous melanomas, while the others are breast metastases from a distant site cutaneous melanoma. In two of the nine primary cutaneous melanomas in-transit metastasis to the breast developed during the follow-up period.


CONCLUSIONS
In this paper, the diagnostic and surgical approach to primary and metastatic melanoma of the breast, and the importance of the breast during the follow-up period are reviewed.
Kurul
Sidika
S
Division of Surgical Oncology, Istanbul Medical School, Turkey. skurul@istanbul.edu.tr
Taş
Faruk
F
Büyükbabani
Nesimi
N
Mudun
Ayşe
A
Baykal
Can
C
Camlica
Hakan
H
D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D001940:Breast; D001943:Breast Neoplasms / Q000556:secondary*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D015412:Mastectomy, Segmental; D008545:Melanoma / Q000175:diagnosis* / Q000556:secondary / Q000601:surgery*; D008875:Middle Aged; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D016038:Skin Transplantation