In vitro fertilization surrogate pregnancy in a patient who underwent radical hysterectomy followed by ovarian transposition, lower abdominal wall radiotherapy, and chemotherapy.
OBJECTIVE
To describe an IVF surrogate pregnancy from a patient who had a radical hysterectomy followed by excision of a laparoscopic port site implantation with ovarian transposition followed by abdominal wall irradiation and chemotherapy, which resulted in premature ovarian failure from which there was partial recovery.


METHODS
Case report.


METHODS
Tertiary referral university women's hospital in Sydney, Australia and private reproductive medicine clinic in California.


METHODS
A 34-year-old woman who underwent laparoscopy for pelvic pain, shortly afterward followed by radical hysterectomy and pelvic lymph node dissection, who subsequently developed a laparoscopic port site recurrence, which was excised in association with ovarian transposition before abdominal wall irradiation and chemotherapy.


METHODS
Modified IVF treatment, transabdominal oocyte retrieval, embryo cryopreservation in Australia, and transfer to a surrogate mother in the United States.


METHODS
Pregnancy.


RESULTS
Miscarriage in the second cycle and a twin pregnancy in the fourth cycle.


CONCLUSIONS
This is the first case report of ovarian stimulation and oocyte retrieval performed on transposed ovaries after a patient developed premature ovarian failure after radiotherapy and chemotherapy with subsequent partial ovarian recovery.
Steigrad
Stephen
S
Department of Reproductive Medicine, Royal Hospital for Women, Randwick NSW, Australia. steigrads@sesahs.nsw.gov.au
Hacker
Neville F
NF
Kolb
Bradford
B
D034861:Abdominal Wall / Q000473:pathology* / Q000528:radiation effects; D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D009865:Oocytes / Q000187:drug effects / Q000528:radiation effects*; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D016649:Primary Ovarian Insufficiency / Q000628:therapy; D013533:Gestational Carriers
D000970:Antineoplastic Agents