title: Therapeutics and prion disease: can immunisation or drugs be effective?
abstract: Prion diseases are of considerable importance because of the threat of a variant form of Creutzfeldt Jakob disease that has emerged in recent years. Pre-clinical diagnosis of prion diseases still remains poor and effective therapies also do not exist at present. This review examines research on possible therapeutic strategies that might have potential benefits if applied before neurodegeneration has occurred.
authors.affiliation: Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK.
authors.forename: J
authors.initials: J
authors.lastname: Sassoon
authors.forename: M
authors.initials: M
authors.lastname: Sadowski
authors.forename: T
authors.initials: T
authors.lastname: Wisniewski
authors.forename: D R
authors.initials: DR
authors.lastname: Brown
mesh_terms: D000818:Animals; D006801:Humans; D007114:Immunization; D051379:Mice; D017096:Prion Diseases / Q000188:drug therapy / Q000628:therapy*; D011328:Prions / Q000276:immunology
chemical_list: D011328:Prions