title: Sulfur-based protecting groups for pyrroles and the facile deprotection of 2-(2,4-dinitrobenzene)sulfinyl and sulfonyl pyrroles.
abstract: [reaction: see text] The effectiveness of simple sulfinyl and sulfonyl groups as electron-withdrawing protecting groups for pyrroles has been analyzed using (13)C NMR spectroscopy and confirmed by consideration of X-ray crystal structures. Additionally, the 2,4-dinitrobenzenesulfinyl and sulfonyl groups are shown to be effective electron-withdrawing protecting groups for pyrroles, and they can be removed by treatment with benzene thiol or thiolate under mild and specific conditions.
authors.affiliation: Department of Chemistry, Dalhousie University, Halifax, Nova Scotia B3H 4J3, Canada alison.thompson@dal.ca
authors.forename: Alison
authors.initials: A
authors.lastname: Thompson
authors.forename: R Jonathan
authors.initials: RJ
authors.lastname: Butler
authors.forename: Meaghan N
authors.initials: MN
authors.lastname: Grundy
authors.forename: Andrea B E
authors.initials: AB
authors.lastname: Laltoo
authors.forename: Katherine N
authors.initials: KN
authors.lastname: Robertson
authors.forename: T Stanley
authors.initials: TS
authors.lastname: Cameron