Synthesis of multivalent aminoglycoside mimics via the Ugi multicomponent reaction.
The synthesis of multivalent neoglycoconjugates with 2,6-diamino-2,6-dideoxyglucose is accomplished by a flexible Ugi multicomponent approach leading to mono-, di- and tri-valent carbohydrate clusters.
Westermann
Bernhard
B
Leibniz Institute of Plant Biochemistry, Department of Bioorganic Chemistry, Weinberg 3, 06120, Halle (Saale), Germany. bwesterm@ipb-halle.de
Dorner
Simon
S
D000617:Aminoglycosides / Q000138:chemical synthesis* / Q000737:chemistry; D005944:Glucosamine / Q000031:analogs & derivatives / Q000737:chemistry; D008968:Molecular Conformation; D018716:Molecular Mimicry; D013237:Stereoisomerism
D000617:Aminoglycosides; C038761:neosamine C; D005944:Glucosamine