title: The crystal structure of a cyclic glycolipid reveals a carbohydrate-carbohydrate interaction interface.
abstract: The crystal structure of an amphiphilic macrocycle [Velasco-Torrijos, T.; Murphy, P. V., Tetrahedron: Asymmetry2005, 16, 261-272] derived from saccharides shows extensive hydrogen-bonding networks, including participation of water, that may have relevance for the modelling of carbohydrate-carbohydrate recognition at cell-cell interfaces. The structure may provide a basis for understanding the binding of the macrocycle to hydrophobic probes.
authors.affiliation: Centre for Synthesis and Chemical Biology, Department of Chemistry, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland. paul.v.murphy@ucd.ie
authors.forename: Paul V
authors.initials: PV
authors.lastname: Murphy
authors.forename: Helge
authors.initials: H
authors.lastname: Müller-Bunz
authors.forename: Trinidad
authors.initials: T
authors.lastname: Velasco-Torrijos
mesh_terms: D002241:Carbohydrates / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006017:Glycolipids / Q000737:chemistry*; D047028:Macrocyclic Compounds / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D002241:Carbohydrates; D006017:Glycolipids; D047028:Macrocyclic Compounds