[Prediction of serotypes of dengue virus by response to IgM antibodies].
A study of 4 groups of serum samples from Cuba, Costa Rica, Nicaragua and Panama was made to determine the serotypes of dengue virus causing epidemics or outbreaks by using IgM antibody-capture ELISA(MAC-ELISA). Dengue-IgM diagnostic kit was independently used in each of the serotypes and an index value was calculated (optical density of the sample/cut-off value) in each case, with which two statistical analyses were made: Fisher's variances and Litter significant difference (LSD) calculation. Such calculations allowed determining that in Cuba and Panama, serotype 2 circulated whereas in Costa Rica, serotype 1 prevailed. These were the isolated serotypes in various epidemics. Regarding Nicaragua, very heterogeneous responses were obtained, the responsible serotype could not be determined since more than two serotypes co-circulated in this country.
Delgado
Iselys
I
Instituto de Medicina Tropical "Pedro Kouri", Ciudad de La Habana, Cuba.
Vásquez
Susana
S
Bravo
José Ramón
JR
Guzmán
Maria Guadalupe
MG
D003716:Dengue Virus / Q000145:classification* / Q000276:immunology*; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology*; D011237:Predictive Value of Tests; D012703:Serotyping
D007075:Immunoglobulin M