Factor V Leiden and its effect on children with cardiac pathology.
Factor V Leiden thrombophilia, formed by a genetic mutation, slows the body's anticoagulation response to clot formation. First described in 1994, factor V Leiden mutation has been identified as a contributing risk factor for venous thromboembolism. Although venous thromboembolism is considered rare in the pediatric population, Factor V Leiden has implications for certain at-risk pediatric patients.
Connor
Jean A
JA
Department of Cardiology, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA. Jean.Connor@cardio.chboston.org
D002648:Child; D005165:Factor V / Q000032:analysis*; D005820:Genetic Testing; D006331:Heart Diseases / Q000235:genetics* / Q000451:nursing / Q000601:surgery; D006801:Humans; D010371:Pediatric Nursing
C095381:factor V Leiden; D005165:Factor V