title: Role of grey scale ultrasound in benign and malignant breast lesions.
abstract: OBJECTIVE
  To evaluate the sensitivity and specificity of ultrasound in diagnosis of benign and malignant disease in correlation with histopathological findings.
  
  
  METHODS
  A comparative study.
  
  
  METHODS
  Diagnostic Radiology Department of PNS Shifa, Karachi, from January 2000 to July 2002.
  
  
  METHODS
  Adult female patients presenting with breast lump were included. Grey-scale ultrasound was done with high frequency probe. Findings were compared with histopathology. The sensitivity and specificity was determined.
  
  
  RESULTS
  Eighty-five female patients with positive clinical findings were differentiated into benign (n =45, 52.9%), intermediate (n =15, 17.6%) and malignant (n =25, 29.4%), by ultrasound examination. Only one (2.2%) benign lesion was found malignant on histopathology, 8 (32%) cases of malignant group were benign on histopathology. The sensitivity of ultrasound for malignant lesion was 95.24% and specificity was 68.75% for a benign lesion. Our results were compatible with international studies.
  
  
  CONCLUSIONS
  Ultrasound of breast is very useful in evaluating breast lumps. This modality is, however, not a good screening tool. When combined with clinical evaluation and mammographic studies, a subset of patients can be identified which do not require biopsy. This will not only save the cost but will also alley the anxiety of patients.
authors.affiliation: Department of Radiology, PNS Shifa, Karachi. rahatshahid2000@yahoo.com
authors.forename: Rahat
authors.initials: R
authors.lastname: Shahid
authors.forename: Abdul
authors.initials: A
authors.lastname: Ghaffar
authors.forename: Ahsin Manzoor
authors.initials: AM
authors.lastname: Bhatti
mesh_terms: D000328:Adult; D001941:Breast Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D016217:Ultrasonography, Mammary