title: Surface analyses and immune reactivities of major cell wall-associated proteins of group a streptococcus.
abstract: A proteomic analysis was undertaken to identify cell wall-associated proteins of Streptococcus pyogenes. Seventy-four distinct cell wall-associated proteins were identified, 66 of which were novel. Thirty-three proteins were immunoreactive with pooled S. pyogenes-reactive human antisera. Biotinylation of the GAS cell surface identified 23 cell wall-associated proteins that are surface exposed.
authors.affiliation: School of Biological Sciences, University of Wollongong, Wollongong, NSW 2522, Australia.
authors.forename: Jason N
authors.initials: JN
authors.lastname: Cole
authors.forename: Ruben D
authors.initials: RD
authors.lastname: Ramirez
authors.forename: Bart J
authors.initials: BJ
authors.lastname: Currie
authors.forename: Stuart J
authors.initials: SJ
authors.lastname: Cordwell
authors.forename: Steven P
authors.initials: SP
authors.lastname: Djordjevic
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Walker
mesh_terms: D001426:Bacterial Proteins / Q000276:immunology* / Q000378:metabolism*; D002473:Cell Wall / Q000378:metabolism*; D015180:Electrophoresis, Gel, Two-Dimensional; D006801:Humans; D040901:Proteomics; D013297:Streptococcus pyogenes / Q000737:chemistry* / Q000276:immunology
chemical_list: D001426:Bacterial Proteins