Development and applications of a software for Functional Image Registration (FIRE).
Image registration with anatomical modalities, such as CT and MRI, facilitates the anatomical identification and localization in the interpretation of nuclear medicine images that lack anatomical information. The implementation of Functional Image Registration (FIRE), an operating system (OS) and platform independent multimodal image registration software is reported. In order to register the images without an operator's interaction, several automatic algorithms were implemented. These include principal axes matching and maximization of the mutual information methods. The user interface was designed to support the manual registration of the images. Fused images were composed by overlaying one image with the other one transparently, in which the opacity of the overlaid image was interactively controlled. FIRE was successfully applied to many clinical cases for which automatic and/or manual registration was required. An OS and platform independent program for image registration developed in this study will be useful for the clinical application of image registration techniques.
Lee
Jae Sung
JS
Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Park
Kwang Suk
KS
Lee
Dong Soo
DS
Lee
Choong Woong
CW
Chung
June-Key
JK
Lee
Myung Chul
MC
D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D006801:Humans; D007089:Image Enhancement; D007090:Image Interpretation, Computer-Assisted; D008279:Magnetic Resonance Imaging; D009683:Nuclear Medicine; D012984:Software; D014057:Tomography, X-Ray Computed; D014584:User-Computer Interface