Hypopyon uveitis associated with systemic lupus erythematosus and antiphospholipid antibody syndrome.
OBJECTIVE
To report a case of hypopyon uveitis associated with systemic lupus erythematosus and antiphospholipid antibody syndrome.


METHODS
Interventional case report: a 49-year-old woman with a history of systemic lupus erythematosus and antiphospholipid antibody syndrome presented with sudden onset of pain, redness, photophobia, and decreased vision in the left eye. Examination revealed hypopyon uveitis and vaso-occlusive retinopathy.


RESULTS
Following treatment with intravenous steroids and cyclophosphamide, the patient's vision improved from CF to 20/80 with no inflammation 6 months following initial presentation.


CONCLUSIONS
In this case, systemic lupus and antiphospholipid syndrome were associated with hypopyon uveitis. Prompt treatment with systemic immunosuppressive therapy resulted in improvement in the hypopyon uveitis and vaso-occlusive retinopathy.
Zink
Jeffrey M
JM
Retina Service, Kellogg Eye Center, University of Michigan, 1000 Wall St., Ann Arbor, MI 48105, USA. jzink@med.umich.edu
Singh-Parikshak
Rita
R
Johnson
C Starck
CS
Zacks
David N
DN
D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008875:Middle Aged; D015356:Retinal Artery Occlusion / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D012170:Retinal Vein Occlusion / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D015829:Uveitis, Suppurative / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014786:Vision Disorders / Q000209:etiology; D014792:Visual Acuity
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide