title: Urinary diversion in children and adolescents with neurogenic bladder: the Mainz experience. Part II: Continent cutaneous diversion using the Mainz pouch I.
abstract: After failure of conservative treatment of neurogenic bladders (deterioration of the upper urinary tract/incontinence) continent cutaneous diversion has to be considered in those patients with irreparable urethral sphincter defects or those who are unable to perform trans-urethral self-catheterization. In this second part of the study we investigated the long-term safety of using the Mainz pouch I with regard to protecting the upper urinary tracts and to provide urine continence. Between 1985 and 2002, operations to form an ileocaecal pouch with umbilical stoma (Mainz pouch I) were performed on 70 children and adolescents of median age 15.3 years (range 5.7-20 years). During the follow-up period five patients died 2.4-14 years postoperatively of causes not related to urinary diversion. A follow-up period of 8.7 years (0.9-18) was achieved in 65 patients with 118 renal units (RUs). As compared to preoperatively, the upper urinary tracts had remained stable or improved in 113/118 RUs (95.8%) at the latest follow-up. Complete continence was achieved in 97% of patients with a continent cutaneous diversion. Surgical revisions were required for: incontinence of the outlet mechanism in 9%, stoma prolapse in 2%, stoma stenosis in 23%, pouch calculi in 15%, symptomatic reflux in 1%, ureter stenosis in 16% of the RUs with submucosal tunnel and in 3% of the RUs with an extramural tunnel. We conclude that, in patients with irreparable sphincter defect and those who are unable to perform urethral self-catheterization, continent cutaneous urinary diversion with the Mainz pouch I provides a high continence rate with preservation of the upper urinary tracts in the long run. In patients with dilated ureters, the extramural tunnel technique results in a lower complication rate.
authors.affiliation: Department of Urology, Johannes Gutenberg University School of Medicine, Langenbeck Strasse 1, 55131 Mainz, Germany. Stein@urologie.klinik.uni-mainz.de
authors.forename: Raimund
authors.initials: R
authors.lastname: Stein
authors.forename: Christoph
authors.initials: C
authors.lastname: Wiesner
authors.forename: Rolf
authors.initials: R
authors.lastname: Beetz
authors.forename: Jesco
authors.initials: J
authors.lastname: Pfitzenmeier
authors.forename: Manfred
authors.initials: M
authors.lastname: Schwarz
authors.forename: Joachim W
authors.initials: JW
authors.lastname: Thüroff
mesh_terms: D000136:Acid-Base Equilibrium; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003672:Defecation; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D011184:Postoperative Period; D012086:Reoperation; D012189:Retrospective Studies; D001750:Urinary Bladder, Neurogenic / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D014547:Urinary Diversion / Q000379:methods*; D014549:Urinary Incontinence / Q000209:etiology / Q000503:physiopathology; D016476:Urinary Reservoirs, Continent / Q000009:adverse effects