title: Lymphoepithelioma-like carcinoma of the uterine cervix: absence of Epstein-Barr virus, but presence of a multiple human papillomavirus infection.
abstract: BACKGROUND
  Cervical lymphoepithelioma-like carcinoma (LELC) is a rare variant of squamous cell carcinoma of the cervix. Association with Epstein-Barr virus (EBV) is still controversial. EBV has been demonstrated in Asian women with cervical LELC. In Western women, human papillomavirus (HPV) might play a role in the etiology.
  
  
  METHODS
  We describe a 44-year-old Caucasian woman with a lymphoepithelioma-like carcinoma of the cervix without EBV, but in the presence of multiple HPV infection.
  
  
  CONCLUSIONS
  Our case supports a possible different pathway of development of cervical LELC in Western women as compared to Asian women.
authors.affiliation: Department of Obstetrics and Gynaecology, Erasmus MC University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands. a.bais@erasmusmc.nl
authors.forename: Aagje G
authors.initials: AG
authors.lastname: Bais
authors.forename: Sjarlot
authors.initials: S
authors.lastname: Kooi
authors.forename: Thea M
authors.initials: TM
authors.lastname: Teune
authors.forename: Patricia C
authors.initials: PC
authors.lastname: Ewing
authors.forename: Anca C
authors.initials: AC
authors.lastname: Ansink
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000821:virology*; D015622:Epithelioid Cells / Q000473:pathology; D020031:Epstein-Barr Virus Infections / Q000150:complications*; D005260:Female; D004854:Herpesvirus 4, Human; D006801:Humans; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000150:complications*; D014412:Tumor Virus Infections / Q000150:complications / Q000821:virology*; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000821:virology*