title: Application of InChI to curate, index, and query 3-D structures.
abstract: The HIV structural database (HIVSDB) is a comprehensive collection of the structures of HIV protease, both of unliganded enzyme and of its inhibitor complexes. It contains abstracts and crystallographic data such as inhibitor and protein coordinates for 248 data sets, of which only 141 are from the Protein Data Bank (PDB). Efficient annotation, indexing, and querying of the inhibitor data is crucial for their effective use for technological and industrial applications. The application of IUPAC International Chemical Identifier (InChI) to index, curate, and query inhibitor structures HIVSDB is described.
authors.affiliation: Biotechnology Division (831), NIST, Gaithersburg, Maryland 20899-8314, USA.
authors.forename: M D
authors.initials: MD
authors.lastname: Prasanna
authors.forename: Jiri
authors.initials: J
authors.lastname: Vondrasek
authors.forename: Alexander
authors.initials: A
authors.lastname: Wlodawer
authors.forename: T N
authors.initials: TN
authors.lastname: Bhat
mesh_terms: D000043:Abstracting and Indexing; D030562:Databases, Protein; D016333:HIV Protease / Q000737:chemistry*; D006801:Humans; D020407:Internet; D008958:Models, Molecular; D011480:Protease Inhibitors / Q000737:chemistry*; D011487:Protein Conformation; D012984:Software
chemical_list: D011480:Protease Inhibitors; D016333:HIV Protease