[An adjustable appliance in treatment of obstructive sleep apnea-hypopnea syndrome].
OBJECTIVE
The research tended to approach applying of adjustable appliance in the treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS).


METHODS
30 OSAHS patients (24 males and 6 females) participated in the adjustable group, with a mean age of (49.9 +/- 9.9) years old. AHI was (33.1 +/- 22.7) per hour. The control group consisted of 30 OSAHS patients wearing ordinary mandibular advancing appliance in the corresponding period, with age, weight and AHI at the same level. Monoblind way was designed to obtain and analyze the therapy differences. Differences in changes of upper airway, mandible and hyoid bone were also analyzed among the doctor-experience position, final adjusted position and original position.


RESULTS
AHI decreased by 85.5% in the adjustable appliance group. The change in AHI was greater significantly (P = 0.025) in the adjustable group than in the control group. In the final adjusted position, the amount of mandibular advancement was (5.8 +/- 1.4) mm [(71 +/- 26)% of the maximum range of protrusion] and that of bite opening (the distance between upper and lower incisor edges) was (4.6 +/- 1.1) mm.


CONCLUSIONS
The adjustable appliance had shown better therapy effect in OSAHS patients. The final adjusted position provided useful information on determining mandibular position using other appliances.
Gao
Xue-mei
XM
Department of Orthodontics, Peking University School of Stomatology, Beijing 100081, China. xmgao@263.net
Zeng
Xiang-long
XL
Fu
Min-kui
MK
Tan
Quan-fa
QF
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D019186:Mandibular Advancement / Q000295:instrumentation*; D008875:Middle Aged; D016037:Single-Blind Method; D020181:Sleep Apnea, Obstructive / Q000628:therapy*; D016896:Treatment Outcome