title: Tuberculous splenic abscess in a neonate with thrombocytopenia.
abstract: We present a case of a premature neonate who presented with anemia and persistent thrombocytopenia. The patient was ultimately diagnosed with disseminated tuberculosis. Initial sonographic evaluation of the abdomen revealed a heterogeneous but predominantly hypoechoic spleen; there was subsequent evolution of a splenic abscess. The patient was treated medically with anti-tubercular drugs. Follow-up post-treatment sonograms of the spleen showed diminution of the abscess and the evolution of multiple calcifications compatible with calcified granulomas. This case is an unusual presentation of tuberculosis in an infant with splenic abscess associated with thrombocytopenia and anemia.
authors.affiliation: Department of Radiology, New York University Medical Center, 560-1st Avenue, NY 10016, USA. John.Amodio@med.nyu.edu
authors.forename: John
authors.initials: J
authors.lastname: Amodio
authors.forename: Darius
authors.initials: D
authors.lastname: Biskup
authors.forename: Rafael
authors.initials: R
authors.lastname: Rivera
authors.forename: Shetal
authors.initials: S
authors.lastname: Shah
authors.forename: Nancy
authors.initials: N
authors.lastname: Fefferman
mesh_terms: D000038:Abscess / Q000000981:diagnostic imaging*; D000995:Antitubercular Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D013921:Thrombocytopenia / Q000209:etiology*; D014400:Tuberculosis, Splenic / Q000150:complications* / Q000000981:diagnostic imaging* / Q000188:drug therapy; D014463:Ultrasonography
chemical_list: D000995:Antitubercular Agents