title: Can chronic subthalamic nucleus stimulation induce de novo tremor in Parkinson's disease?
abstract: Subthalamic nucleus stimulation dramatically improves parkinsonian symptoms, notably the tremor. The occurrence of a tremor in the first 6 months after the surgical procedure in patients without tremor preoperatively is much less common. We report on the cases of 3 patients who developed such modification of their parkinsonian symptomatology. Physiopathological hypotheses are discussed.
authors.affiliation: Sobell Department of Motor Neurosciences and Movement Disorders, Unit of Functional Neurosurgery, Institute of Neurology, London, United Kingdom. s.thobois@ion.ucl.ac.uk
authors.forename: Stephane
authors.initials: S
authors.lastname: Thobois
authors.forename: Stephen
authors.initials: S
authors.lastname: Tisch
authors.forename: Jing
authors.initials: J
authors.lastname: Xie-Brustolin
authors.forename: Patrick
authors.initials: P
authors.lastname: Mertens
authors.forename: Marwan I
authors.initials: MI
authors.lastname: Hariz
authors.forename: Isabelle
authors.initials: I
authors.lastname: Benatru
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Broussolle
authors.forename: Patricia
authors.initials: P
authors.lastname: Limousin-Dowsey
mesh_terms: D000368:Aged; D046690:Deep Brain Stimulation / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000601:surgery*; D020531:Subthalamic Nucleus / Q000503:physiopathology / Q000528:radiation effects*; D014202:Tremor / Q000209:etiology*