title: [Effect of sulphurous Bioglea on psoriasis].
abstract: OBJECTIVE
  The efficacy of biological sulphurous Bioglee on psoriasis was investigated using an organic matrix derived from the metabolism of microflora growing in shallow hyper thermal waters possessing high sulphur concentrations and in thermal mud at Guardia Piemontese-Acquappesa (CS). Such a matrix forms part of the "Sulphuretum" ecological matrix which is dominated by cyanobacteria and sulfobacteria. The effect of this matrix on psoriasis was evaluated through the typical symptoms such as desquamation, cutaneous erythema and itching.
  
  
  METHODS
  The study was carried out on 20 patients wich gave informed consent, suffering from psoriasis. Image analysis was used to monitor the intensity of psoriasic lesions prior to and at the conclusion of the therapy which consisted of topical applications of the thermal matrices twice a day for 12 days.
  
  
  RESULTS
  Image analysis illustrated a reduction in the intensity of psoriasic lesions at the conclusion of the therapy with significant reductions in desquamation, erythema and itching.
  
  
  CONCLUSIONS
  The anti-psoriasic action of the thermal matrix used in this study may be attributable to the substances such as carotene, hydro and lipo-soluble vitamins and naturally occuring phytosterols. These substances may not only be anti-inflammatory but may also work synergistically with the mineral components of the thermal matrix to attenuate the symptoms of psoriasis.
authors.affiliation: Dipartimento di Biologia Cellulare, Università della Calabria, Arcavacata di Rende, CS, Italia. mazzulla@unical.it
authors.forename: S
authors.initials: S
authors.lastname: Mazzulla
authors.forename: R
authors.initials: R
authors.lastname: Chimenti
authors.forename: S
authors.initials: S
authors.lastname: Sesti
authors.forename: S
authors.initials: S
authors.lastname: De Stefano
authors.forename: M
authors.initials: M
authors.lastname: Morrone
authors.forename: G
authors.initials: G
authors.lastname: Martino
mesh_terms: D000328:Adult; D000368:Aged; D001452:Balneology; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000628:therapy*; D013455:Sulfur
chemical_list: D013455:Sulfur