title: [Progress on the vaccine for anthrax].
abstract: Bacillus anthracis is the causative organism of the potentially fatal disease anthrax, and the used vaccines have some disadvantages. There are new developments appeared for the Bacillus anthracis in recent years, such as anti-PA antibody kills the spore of Bacillus anthracis, mucosal immunization induces immune responses in both systemic and secretory immune compartments, Poly (gamma-D-PGA) protein induce IgG antibodies to the vegetative bacteria, new pathogens were found by genomic analysis. The DNA vaccine and live vector vaccine will be the next generation vaccines for anthrax. It will have a shorter immunization schedule and will be greater protective efficacy than before.
authors.affiliation: Institute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China. rmjl727@yahoo.com.cn
authors.forename: De-wen
authors.initials: DW
authors.lastname: Zhan
authors.forename: Peng
authors.initials: P
authors.lastname: Wang
authors.forename: Ling-chun
authors.initials: LC
authors.lastname: Wang
authors.forename: Zhao-shan
authors.initials: ZS
authors.lastname: Zhang
mesh_terms: D000881:Anthrax / Q000276:immunology* / Q000517:prevention & control; D022122:Anthrax Vaccines / Q000276:immunology*; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D001408:Bacillus anthracis / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis; D011099:Polyglutamic Acid / Q000276:immunology; D019444:Vaccines, DNA / Q000276:immunology
chemical_list: D022122:Anthrax Vaccines; D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D019444:Vaccines, DNA; D011099:Polyglutamic Acid