title: [Preliminary study on autoregulation of samR involved in development and differentiation of Streptomyces ansochromogenes].
abstract: The previous result showed that samR plays an important role in the development progress of Streptomyces ansochromogenes. It was reported that the differentiation progress of S. ansochromogenes was accelerated by a recombinant plasmid containing an extra copy of samR gene. However, the differentiation progress of S. ansochromogenes was not further accelerated by a multicopy plasmid containing samR gene. Electrophoresis mobility shift assay (EMSA) demonstrated that SamR binds to its own promoter region specifically. All these results hint that samR is an autoregulatory gene in Streptomyces ansochromogenes.
authors.affiliation: Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, China. yanghh@sun.im.ac.cn
authors.forename: Yan-ling
authors.initials: YL
authors.lastname: Yang
authors.forename: Hai-hua
authors.initials: HH
authors.lastname: Yang
authors.forename: Hua-rong
authors.initials: HR
authors.lastname: Tan
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000502:physiology*; D018628:Gene Dosage; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D010957:Plasmids / Q000235:genetics; D013171:Spores, Bacterial / Q000502:physiology; D013302:Streptomyces / Q000235:genetics* / Q000502:physiology
chemical_list: D001426:Bacterial Proteins