Lack of response to imatinib mesylate as second-line therapy in a patient with c-kit positive metastatic soft tissue leiomyosarcoma.
Silvestris
Nicola
N
Parra
Hector Soto
HS
Angelini
Francesco
F
Di Cosimo
Serena
S
D'Aprile
Modesto
M
Santoro
Armando
A
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001549:Benzamides; D014408:Biomarkers, Tumor / Q000032:analysis*; D006801:Humans; D000068877:Imatinib Mesylate; D007890:Leiomyosarcoma / Q000737:chemistry / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000627:therapeutic use*; D019009:Proto-Oncogene Proteins c-kit / Q000032:analysis*; D011743:Pyrimidines / Q000627:therapeutic use*; D017211:Treatment Failure
D000970:Antineoplastic Agents; D001549:Benzamides; D014408:Biomarkers, Tumor; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate; D019009:Proto-Oncogene Proteins c-kit