Large or multiple congenital melanocytic nevi: occurrence of cutaneous melanoma in 1008 persons.
BACKGROUND
There is a dearth of information regarding the occurrence of cutaneous melanoma in a large cohort of persons with large congenital melanocytic nevi (LCMN) or multiple congenital melanocytic nevi (MCMN).


OBJECTIVE
The purpose of this article is to report our experience with 1008 persons having LCMN and MCMN.


METHODS
Information was evaluated that was obtained from a database of persons with LCMN or MCMN voluntarily submitted by the affected persons to a nevus support group, the Nevus Network.


RESULTS
Of those with garment LCMN, 2.9% developed cutaneous melanoma associated with 0.8% deaths. Of those with LCMN on the head or extremity, 0.3% developed cutaneous melanoma associated with no deaths to date. Of the small number with MCMN without a giant nevus, 6.7% developed cutaneous melanoma.


CONCLUSIONS
Attending physician confirmation of submitted information was unavailable. Conclusions LCMN and MCMN were associated with a low occurrence of cutaneous melanoma in our group.
Bett
Bari Joan
BJ
info@nevusnetwork.org
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008545:Melanoma / Q000209:etiology*; D008548:Melanosis / Q000150:complications; D020752:Neurocutaneous Syndromes / Q000150:complications; D009508:Nevus, Pigmented / Q000150:complications / Q000151:congenital* / Q000628:therapy; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D012657:Self-Help Groups / Q000706:statistics & numerical data; D012878:Skin Neoplasms / Q000209:etiology*