Laser diffraction for standardization of heterogeneous pharmaceutical preparations.
A new quantitative method for standardization of heterogeneous pharmaceutical preparations and their quality control during storage based on laser diffraction is proposed. A series of pharmaceutical dosage forms--suspensions, emulsions, tinctures, decoctions, cell preparations and others, are heterogeneous medicines. In some cases disperse phase can be formed during storage as a result of layering (L1/L2) or precipitation (S/L). Laser diffraction method proposed in this study can be used for standardization and quality control of medicines.
Syroeshkin
A V
AV
Department of Pharmaceutical and Toxicological Chemistry, Faculty of Medicine, Peoples Friendship University of Russia, Moscow, Russia.
Popov
P I
PI
Grebennikova
T V
TV
Frolov
V A
VA
Pleteneva
T V
TV
D007834:Lasers / Q000592:standards; D004364:Pharmaceutical Preparations / Q000032:analysis* / Q000592:standards*; D012015:Reference Standards
D004364:Pharmaceutical Preparations