title: The relationship of functional status, nutritional assessment, and severity of illness to in-hospital mortality.
abstract: BACKGROUND
  Prediction of in-hospital mortality may direct hospital resources towards those patients most at risk. A number of single domain risk instruments have been developed, indicating that functional status, nutritional assessment, and severity of illness individually predict in-hospital mortality. The interaction among these predictors is less well described.
  
  
  OBJECTIVE
  To determine the relationship of functional status, nutritional assessment, and severity of illness to in-hospital mortality.
  
  
  METHODS
  Cohort study of 1712 consecutive admissions over a one year period to an Internal Medical Service at a tertiary university teaching hospital.
  
  
  METHODS
  Death during hospital admission.
  
  
  RESULTS
  Dependency in activities of daily living (OR = 3.37, 95% CI 1.78 to 6.37, p = 0.0002) and body mass index less than 20 (OR = 2.38, 95% CI 1.20 to 4.74, p = 0.01) predicted in-hospital mortality after adjusting for nutritional risk assessment, and severity of illness score.
  
  
  CONCLUSIONS
  Impairment in functional status and low body mass index produce the best predictors of inhospital mortality, after adjusting for nutritional risk and severity of illness score. Among these factors, functional impairment may be amenable to correction.
authors.affiliation: Division of Geriatric Medicine, Saint Louis Health Sciences Center and, GRECC, Veterans Administration Center, MO 63104, USA. thomasdr@sslu.edu
authors.forename: D R
authors.initials: DR
authors.lastname: Thomas
authors.forename: H
authors.initials: H
authors.lastname: Kamel
authors.forename: M
authors.initials: M
authors.lastname: Azharrudin
authors.forename: A S
authors.initials: AS
authors.lastname: Ali
authors.forename: A
authors.initials: A
authors.lastname: Khan
authors.forename: U
authors.initials: U
authors.lastname: Javaid
authors.forename: J E
authors.initials: JE
authors.lastname: Morley
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D004032:Diet; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D016013:Likelihood Functions; D008297:Male; D008875:Middle Aged; D008923:Missouri; D015596:Nutrition Assessment; D012044:Regression Analysis; D012709:Serum Albumin / Q000378:metabolism; D012720:Severity of Illness Index
chemical_list: D012709:Serum Albumin