Eosinophilic fasciitis successfully treated with cyclosporine.
We report on a 45-year-old female who developed eosinophilic fasciitis, characterized by scleroderma-like skin indurations, predominantly on the extremities and chest, with joint contractures and intermittent blood eosinophilia. Histologic examination revealed fibrosis of muscle fascia and eosinophilic infiltration. High-dose systemic corticosteroid therapy was ineffective, but cyclosporine treatment led to remission.
Bukiej
Aleksandra
A
Department of Medicine, Jagiellonian University School of Medicine, Cracow, Poland.
Dropiński
Jerzy
J
Dyduch
Grzegorz
G
Szczeklik
Andrzej
A
D016572:Cyclosporine / Q000627:therapeutic use*; D004802:Eosinophilia / Q000188:drug therapy* / Q000473:pathology; D005208:Fasciitis / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D005355:Fibrosis / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology; D012074:Remission Induction; D016896:Treatment Outcome
D007166:Immunosuppressive Agents; D016572:Cyclosporine