Type III cryoglobulinemia complicated by renal cortical necrosis.
Renal involvement is rare in patients with type III cryoglobulinemia. We report a case of renal cortical necrosis in a patient with type III cryoglobulinemia. Renal function improved partially after treatment with plasma exchange, steroids, and cyclophosphamide. Renal magnetic resonance imaging was a valuable tool in the evaluation of the extent of renal cortical necrosis and improvement in renal vascularization after treatment.
Thaunat
Olivier
O
Department of Nephrology, AP-HP, Hôpital Necker Enfants Malades, Paris, France.
Aaron
Laurent
L
Desbene
Cédric
C
Noël
Laure-Hélène
LH
Karras
Alexandre
A
Lesavre
Philippe
P
Alyanakian
Marie-Alexandra
MA
Fakhouri
Fadi
F
D001172:Arthritis, Rheumatoid / Q000150:complications; D001706:Biopsy; D003131:Combined Modality Therapy; D003449:Cryoglobulinemia / Q000145:classification / Q000150:complications* / Q000188:drug therapy / Q000628:therapy; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006111:Graves Disease / Q000150:complications; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use; D007673:Kidney Cortex Necrosis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D008875:Middle Aged; D010956:Plasmapheresis; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D014581:Urticaria / Q000150:complications
D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D011241:Prednisone; D008775:Methylprednisolone