The singleton, term gestation, and live birth rate per cycle initiated: a 1-year experience in in vitro fertilization cycles with native and donated oocytes.
OBJECTIVE
To investigate the singleton, term gestation, and live birth rate per cycle initiated in our IVF program during a 1-year period.


METHODS
Retrospective study of all first IVF cycles performed in the year 2002, with or without intracytoplasmic sperm injection (ICSI), with day 2/3 embryo transfer and using native or donated oocytes.


METHODS
Instituto Valenciano de Infetilidad (IVI), Valencia, Spain.


METHODS
Of 3,158 IVF cycles initially considered, 165 were excluded because of embryo freezing, follow-up loss, or embryo reduction. Of the remaining cycles, only 1,836 were first cycles with day 2/3 embryo transfer; of these, native oocytes were employed in 1,095 and donated oocytes in 741.


METHODS
No patient underwent any additional procedure or intervention.


METHODS
The singleton, term gestation, and live birth rate per cycle initiated was used as a primary outcome measure. Results were analyzed according to the origin of the oocytes (native vs. donated) and the woman's age (<37 and > or =37 years old).


RESULTS
The ectopic pregnancy rate was higher in the native oocyte group. The singleton, term gestation, and live birth rate per cycle initiated was similar in native and donated oocyte groups (15.3% vs. 13.4%). In the native oocyte group, patients <37 years old showed a significantly better outcome. The singleton, term gestation, and live birth rate per cycle initiated was 16.7% and 10.8% in younger and older women, respectively.


CONCLUSIONS
The singleton, term gestation, and live birth rate per cycle initiated constitutes an essential parameter for determining the real possibility of a healthy baby for a specific assisted reproduction technology (ART).
Bellver
José
J
Department of Infertility and Maternal-Fetal Medicine, Instituto Valenciano de Infertilidad, Valencia, Spain. jbellver@sego.es
Albert
Carmela
C
Soares
Sérgio R
SR
Alvarez
Claudio
C
Pellicer
Antonio
A
D000328:Adult; D001723:Birth Rate / Q000639:trends*; D004624:Embryo Transfer / Q000706:statistics & numerical data / Q000639:trends; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods / Q000706:statistics & numerical data* / Q000639:trends; D005865:Gestational Age; D006801:Humans; D007223:Infant; D018587:Oocyte Donation / Q000379:methods / Q000706:statistics & numerical data* / Q000639:trends; D009865:Oocytes / Q000502:physiology; D011247:Pregnancy; D011272:Pregnancy, Multiple / Q000706:statistics & numerical data; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods / Q000706:statistics & numerical data / Q000639:trends; D047929:Term Birth