title: [The endoscopic extended transsphenoidal surgery for gigantic pituitary adenoma].
abstract: OBJECTIVE
  The purpose of the study is to evaluate the ability of endoscopic extended transsphenoidalapproach for treatment of gigantic pituitary adenoma.
  
  
  METHODS
  The clinical data of 13 cases with gigantic pituitary adenoma treated by endoscopic extended transsphenoidalapproach was studied retrospectively.
  
  
  RESULTS
  The tumor of all patients was total resection in endoscopes. Postoperative 10 Patients received radiotherapy. In postoperative MRI examination, there was remnant of tumor in 6 patients. There were no regrowth or recurrence during 12 months postoperative. Six patients occurred transient diabetes insipidus, 2 patients with transient cerebrospinal rhinorrhoea cured by conservative therapy. One patient occurred acute hypopituitarism postoperatively. There were no death or intracranial infection and nasal complication such as nasal adherence in all patients.
  
  
  CONCLUSIONS
  The extended transsphenoidalapproach can be used for treatment of gigantic pituitary tumor. The surgeon should be familiarity with the sellar and parasellar anatomy and skilled with transsphenoidal surgery.
authors.affiliation: Department of Otolaryngology-Skull Base Surgery, Xuanwu Hospital, Capital Medical Science University, Beijing, 100053, China. liuhaisheng1973@yahoo.com
authors.forename: Haisheng
authors.initials: H
authors.lastname: Liu
authors.forename: Qingfeng
authors.initials: Q
authors.lastname: Zhang
authors.forename: Zhanquan
authors.initials: Z
authors.lastname: Yang
authors.forename: Yuxin
authors.initials: Y
authors.lastname: Sun
mesh_terms: D000236:Adenoma / Q000601:surgery*; D000328:Adult; D000368:Aged; D004724:Endoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007016:Hypophysectomy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000601:surgery*; D012189:Retrospective Studies