Inhibitory effect of the plant Boerhavia diffusa l. against the dermatophytic fungus Microsporum fulvum.
Antifungal activity (reduction in colony diameter) of various extracts (pt. ether, chloroform, ethyl acetate, ethyl alcohol and aqueous) of aerial and root parts of Boerhavia diffusa (Nictaginaceae) was screened against dermatophytic fungi Microsporum fulvum. Statistically significant increase has been recorded in the % inhibition of the target fungal species with increasing test concentrations (1000-5000 ppm) of chloroform, ethyl acetate and ethyl alcohol extracts of the root. The maximum % inhibition observed in various solvent extracts of root was about 26% (chloroform), 46% (ethyl alcohol) and 57% (ethyl acetate) at 5000 ppm concentration with time exposure of 10 days. The colony diameter of the target mycelial colony decreased with increasing supplementation of the phytoextract, showing the presence of significant amount of some antifungal phytochemical moiety.
Agrawal
Anurag
A
Department of Chemistry, Faculty of Science, Dayalbagh Educational Institute, Dayalbagh, Agra-282 005, India.
Srivastava
Shalini
S
Srivastava
J N
JN
Srivastava
M M
MM
D000085:Acetates / Q000737:chemistry; D000935:Antifungal Agents / Q000494:pharmacology*; D002725:Chloroform / Q000737:chemistry; D000431:Ethanol / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D008864:Microsporum / Q000187:drug effects* / Q000254:growth & development; D039281:Nyctaginaceae / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology; D010937:Plant Growth Regulators / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
D000085:Acetates; D000935:Antifungal Agents; D010936:Plant Extracts; D010937:Plant Growth Regulators; D000431:Ethanol; C007650:ethyl acetate; D002725:Chloroform