Haloxylines A and B, antifungal and cholinesterase inhibiting piperidine alkaloids from Haloxylon salicornicum.
Haloxylines A (1) and B (2), new piperidine alkaloids, have been isolated from the chloroform soluble fraction of Haloxylon salicornicum and their structures elucidated by spectroscopic techniques including 2D-NMR. Both the compounds displayed antifungal and cholinesterase enzymes inhibitory potentials.
Ferheen
Sadia
S
Pharmaceutical Research Center, PCSIR Laboratories Karachi Complex, Karachi-75280, Pakistan.
Ahmed
Ejaz
E
Afza
Nighat
N
Malik
Abdul
A
Shah
Muhammad Raza
MR
Nawaz
Sarfraz Ahmad
SA
Choudhary
Muhammad Iqbal
MI
D000110:Acetylcholinesterase / Q000378:metabolism; D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D027703:Amaranthaceae; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects; D002800:Cholinesterase Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010880:Piperidines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018514:Plant Structures
D000470:Alkaloids; D000935:Antifungal Agents; D002800:Cholinesterase Inhibitors; D010880:Piperidines; D010936:Plant Extracts; D000110:Acetylcholinesterase