Bacteriophage Mu targets the trinucleotide sequence CGG.
Target specificity for bacteriophage Mu was studied using a new phage derivative that enabled cloning of Mu-host junctions from phage DNA. Insertions distributed throughout the chromosome showed no orientation bias with respect to transcription or replication polarity. Genes with a high frequency of the triplet CGG were preferred targets.
Manna
Dipankar
D
Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.
Deng
Shuang
S
Breier
Adam M
AM
Higgins
N Patrick
NP
D000595:Amino Acid Sequence; D010583:Bacteriophage mu / Q000235:genetics*; D002876:Chromosomes, Bacterial; D016384:Consensus Sequence; D004279:DNA, Viral / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics* / Q000821:virology*; D008969:Molecular Sequence Data; D018741:Replication Origin / Q000235:genetics; D018911:Trinucleotide Repeats
D004279:DNA, Viral