[Studies on anti-HSV effect of Ficus carica leaves].
OBJECTIVE
To study the anti-HSV effect of the extract from the leaves of Ficos carica.


METHODS
The effective ingredient was extracted from the leaves of Ficus carica, and the anti-virus effect was observed on Hep-2, BHK21 and PRK cells.


RESULTS
The water extract from the leaves of Ficus carica possessed distinct anti-HSV-1 effect. The MTC was 0.5 mg/ml, TDO was 15 mg/ml, and TI was 30.0. It possessed low toxicity and directly killing-virus effect on HSV-1.


CONCLUSIONS
The leaves of Ficus carica possess anti-HSV-1 effect, and their application on the area of medicine, food and drugs has expansive foreground.
Wang
Guiting
G
School of Public Health, Shandong University, Jinan 250012.
Wang
Hao
H
Song
Yanyan
Y
Jia
Cunxian
C
Wang
Zhiyu
Z
Xu
Hongzhi
H
D000818:Animals; D000998:Antiviral Agents / Q000302:isolation & purification / Q000494:pharmacology*; D002478:Cells, Cultured / Q000187:drug effects; D004267:DNA Viruses / Q000187:drug effects; D030681:Ficus / Q000737:chemistry*; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D011817:Rabbits; D018139:Simplexvirus / Q000187:drug effects*; D014779:Virus Replication / Q000187:drug effects
D000998:Antiviral Agents; D010936:Plant Extracts