Failure to find progressive temporal lobe volume decreases 10 years subsequent to a first episode of schizophrenia.
The present study used magnetic resonance imaging to examine the volumes of the temporal lobe and the superior temporal gyrus in a 10-year follow-up study of 27 patients with schizophrenia and 10 controls. No change over time was observed in these structures when patients were compared with controls. These results do not support the notion that progressive temporal lobe deterioration occurs in schizophrenia.
DeLisi
Lynn E
LE
Department of Psychiatry, New York University, Center for Advanced Brain Imaging, Nathan S. Kline Institute for Psychiatric Research, New York, NY 10016, USA. DeLisi76@AOL.com
Hoff
Anne L
AL
D000328:Adult; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012559:Schizophrenia / Q000503:physiopathology*; D013702:Temporal Lobe / Q000002:abnormalities* / Q000503:physiopathology*