Effect of chronic total coronary occlusion on treatment strategy.
In a registry analysis of 8,004 consecutive patients presenting for diagnostic catheterization at a single institution from 1990 to 2000, chronic total occlusion (CTO) was found in 52% of patients with significant (> or = 70% diameter stenosis) coronary artery disease. Peripheral vascular disease was the strongest clinical predictor of the presence of a CTO. In a multivariate analysis, CTO was the strongest predictor against the selection of percutaneous coronary intervention (PCI) as a treatment strategy, indicating that efforts to improve the success rate of PCI in CTO may have a significant impact on management of coronary disease.
Christofferson
Ryan D
RD
Division of Cardiovascular Diseases, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Lehmann
Kenneth G
KG
Martin
Gary V
GV
Every
Nathan
N
Caldwell
James H
JH
Kapadia
Samir R
SR
D015906:Angioplasty, Balloon, Coronary; D006328:Cardiac Catheterization; D002908:Chronic Disease; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000601:surgery / Q000628:therapy*; D023921:Coronary Stenosis / Q000175:diagnosis* / Q000601:surgery / Q000628:therapy*; D003657:Decision Making; D006801:Humans; D008875:Middle Aged; D016017:Odds Ratio; D012042:Registries