title: [Detection of antirabic antibodies in personnel at risk through the use of the neutralization technique by reducing the number of plaques].
abstract: The neutralization technique by reducing the number of plaques (NRNP) for detecting antirabic antibodies in personnel at risk was used. Serum samples from individuals at high risk and from persons with vaccination antecedents and without them were studied. The neutralization technique was compared with the biological technique in mouses and as a result of the study it was obtained a concordance of 100%. It was found that sex does not influence on the response of the antibodies to this virus, although the direct contact and the number of times that the individual has received the vaccine act positively on the immune response. The introduction of this technique in the laboratory allows to have a useful tool for the follow-up of the personnel receiving the vaccine before and after being exposed to the rabies virus.
authors.affiliation: Instituto de Medicina Tropical "Pedro Kourí", Ciudad de La Habana, Cuba. ciipk@ipk.sld.cu
authors.forename: María de los A
authors.initials: Mde L
authors.lastname: Ribas
authors.forename: Arlene
authors.initials: A
authors.lastname: Rebull
authors.forename: Gisset
authors.initials: G
authors.lastname: Torres
authors.forename: Maylin
authors.initials: M
authors.lastname: Alvarez
authors.forename: Luis
authors.initials: L
authors.lastname: Morier
authors.forename: Yahisel
authors.initials: Y
authors.lastname: Tejero
authors.forename: Deneb
authors.initials: D
authors.lastname: García
authors.forename: Carina
authors.initials: C
authors.lastname: Rodríguez
mesh_terms: D000818:Animals; D000906:Antibodies / Q000097:blood*; D005260:Female; D006801:Humans; D007106:Immune Sera; D008297:Male; D051379:Mice; D009500:Neutralization Tests; D016273:Occupational Exposure; D011818:Rabies / Q000276:immunology*; D012307:Risk Factors
chemical_list: D000906:Antibodies; D007106:Immune Sera