Usefulness of low-dose dobutamine stress echocardiography for the evaluation of spontaneous recovery of stunned myocardium in patients with acute right ventricular infarction.
Right ventricular (RV) infarction (RVI) is usually associated with severe RV global dysfunction representing predominantly stunned myocardium that may respond favorably to reperfusion. We assessed the efficacy of low-dose dobutamine stress echocardiography (DSE), performed early in the course of a reperfused RVI, to predict the recovery of RV systolic and diastolic function in 3 months, documenting the recovery of stunned myocardium. In all, 27 patients with acute, successfully thrombolyzed RVI comprised the study population. All patients underwent standard echocardiography at baseline and 3 months later for evaluation of RV systolic and diastolic function. At day 5 DSE was performed for evaluation of RV contractile reserve. Of the total number of segments analyzed, 69% were detected as stunned. At baseline, RV systolic and diastolic indices were seriously impaired showing significant improvement at follow-up. RV wall-motion score index during DSE was positively correlated with the same index at follow-up. DSE is a safe and precise modality to predict recovery of stunned myocardium in the setting of RVI.
Karvounis
Haralampos I
HI
First Cardiology epartment, AHEPAUniversity Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Papadopoulos
Christodoulos E
CE
Ketikoglou
Dimitrios G
DG
Zaglavara
Theodora A
TA
Parharidis
Georgios E
GE
Louridas
Georgios E
GE
D002316:Cardiotonic Agents; D004280:Dobutamine; D025401:Echocardiography, Stress; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology*; D017682:Myocardial Stunning / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests
D002316:Cardiotonic Agents; D004280:Dobutamine