Homozygous factor V Leiden mutation in two siblings presenting with acute myocardial infarction: a rare cause of myocardial infarction in the young.
Although factor V Leiden mutation, is the most common established genetic risk factor for venous thrombosis, its effect on the development of myocardial infarction remains unclear. We describe a family case of homozygous factor V Leiden mutation in two siblings presenting with acute myocardial infarction as a rare cause of myocardial infarction in the young.
Kaykçoğlu
Meral
M
Department of Cardiology, Ege University, Medical School, 11/2 Bornova Izmir, Turkey. mekay@med.ege.edu.tr
Hasdemir
Can
C
Eroğlu
Zuhal
Z
Kosova
Buket
B
Can
Levent H
LH
Ildizli
Muge
M
Yavuzgil
Oguz
O
Payzin
Serdar
S
Turkoglu
Cuneyt
C
D000328:Adult; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging / Q000235:genetics; D004562:Electrocardiography; D005165:Factor V / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006720:Homozygote; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000235:genetics*; D010375:Pedigree; D017354:Point Mutation; D035781:Siblings
C095381:factor V Leiden; D005165:Factor V