title: Combined-type osteosarcoma in a rhesus macaque.
abstract: A femoral mass from a 15-year-old rhesus macaque was evaluated. Grossly, the mass consisted of a large, osteolytic focus in the distal femur, a gelatinous core of neoplastic tissue in the medullary cavity, and an invasive mass-obliterating musculature of the thigh. On histopathologic evaluation, three neoplastic mesenchymal cell populations, osteoblasts, fibroblasts, and primitive mesenchymal cells were identified. The mass was diagnosed as a combined type osteosarcoma. To our knowledge, this is the first osteosarcoma in a rhesus macaque with this subclassification.
authors.forename: S L
authors.initials: SL
authors.lastname: Beam
mesh_terms: D000671:Amputation, Surgical / Q000662:veterinary; D000818:Animals; D005266:Femoral Neoplasms / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D005269:Femur / Q000000981:diagnostic imaging; D006652:Histological Techniques / Q000662:veterinary; D008253:Macaca mulatta; D008992:Monkey Diseases / Q000473:pathology* / Q000601:surgery; D012516:Osteosarcoma / Q000145:classification / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D011859:Radiography