title: Intravascular lymphomatosis presenting with sudden hearing loss.
abstract: Intravascular lymphoma (IVL) is a rare disorder characterized by the aggregation of malignant large cell lymphoma cells in small vessels. Neurological manifestations are typically the initial and, often the only, clinically obvious consequences of this malignancy. Diagnosis is dependent on biopsy or postmortem demonstration of the intravascular tumor. We report a patient in whom sudden hearing loss heralded IVL and propose that the hearing loss may have been the consequence of labyrinthine infarction consequent to the aggregation of malignant cells in the internal auditory artery.
authors.affiliation: Department of Neurology, University of Kentucky College of Medicine, Lexington, KY 40536-0284, USA. jrbneuro@uky.edu
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Berger
authors.forename: Raleigh
authors.initials: R
authors.lastname: Jones
authors.forename: Dianne
authors.initials: D
authors.lastname: Wilson
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001299:Audiometry; D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology; D002531:Cerebellum / Q000473:pathology; D003337:Corpus Callosum / Q000473:pathology; D017809:Fatal Outcome; D003639:Hearing Loss, Sudden / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone