title: Photo-onycholysis due to sparfloxacin.
abstract: This paper describes a case of sparfloxacin-induced photodermatitis associated with photo-onycholysis in a 36-year-old man. He was being treated with sparfloxacin, streptomycin, ethambutol and pyrazinamide for pulmonary tuberculosis. He developed an exaggerated sunburn-like rash over the face and the dorsa of hands and feet, and painful onycholysis of finger- and toe-nails. Withdrawal of sparfloxacin resulted in resolution of the skin rash and nail tenderness.
authors.affiliation: Department of Dermatology, Venereology and Leprosy, Indira Gandhi Medical College, Shimla, India.
authors.forename: Vikram K
authors.initials: VK
authors.lastname: Mahajan
authors.forename: Nand Lal
authors.initials: NL
authors.lastname: Sharma
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects*; D003937:Diagnosis, Differential; D024841:Fluoroquinolones / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009262:Nails / Q000473:pathology*; D010787:Photosensitivity Disorders / Q000139:chemically induced / Q000175:diagnosis* / Q000473:pathology; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents; D024841:Fluoroquinolones; C061363:sparfloxacin