title: Olfactory neuroblastoma: a case report and review of the literature.
abstract: Malignant tumors of the nasal cavity are rare. We report the case of an elderly woman who consulted us with a 4-year history of progressive nasal obstruction, occasional epistaxis, facial pain, and watering of the eyes. A diagnosis of olfactory neuroblastoma was established by histopathology and confirmed by immunohistochemistry. On staging, the mass was classified as a Kadish stage B tumor. The mass was excised via a lateral rhinotomy approach, and the tumor was peeled away completely from the cribriform plate with endoscopes. The patient underwent postoperative radiation, and she was free of recurrence at follow-up 15 months later.
authors.affiliation: Section of Otolaryngology-Head and Neck Surgery, Department of Surgery, Aga Khan University Hospital, Stadium Rd., Karachi-74800, Pakistan. sgm@akunet.org
authors.forename: Shehzad
authors.initials: S
authors.lastname: Ghaffar
authors.forename: Iftikhar
authors.initials: I
authors.lastname: Salahuddin
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D003131:Combined Modality Therapy; D018304:Esthesioneuroblastoma, Olfactory / Q000473:pathology* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009296:Nasal Cavity; D015508:Nasal Obstruction / Q000175:diagnosis / Q000209:etiology; D009361:Neoplasm Invasiveness / Q000473:pathology*; D009367:Neoplasm Staging; D009669:Nose Neoplasms / Q000473:pathology* / Q000628:therapy; D018714:Radiotherapy, Adjuvant; D018570:Risk Assessment; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome