Groin angiosarcoma following radiotherapy for vulvar cancer.
BACKGROUND
Angiosarcomas account for less than 2% of all sarcomas. However, they represent 15% of radiotherapy-induced sarcomas, usually associated to the treatment for breast cancer, cervical cancer, and lymphomas.


METHODS
We report the case of a 56-year-old patient who developed a soft tissue angiosarcoma in the right groin 25 years after receiving radiotherapy for vulvar cancer. To our knowledge, this is the second case reported of a soft tissue angiosarcoma after radiotherapy for a vulvar cancer.


CONCLUSIONS
Postradiation sarcoma must be considered in patients with a history of a previous tumor when a soft tissue mass is seen in the previously irradiated field, especially if the latent period is more than 3 or 5 years. The correct histologic interpretation of such lesions is important because it may result in early identification of the secondary malignancy and may contribute to better management and improved prognosis.
Sanz
Clara
C
Gynecology Department, Hospital La Paz, Madrid, Spain.
Moreno
Fernando
F
Armas
Alvaro
A
Casado
Antonio
A
Castillo
M C
MC
D005260:Female; D006119:Groin; D006394:Hemangiosarcoma / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects; D014846:Vulvar Neoplasms / Q000532:radiotherapy*