title: Groin angiosarcoma following radiotherapy for vulvar cancer.
abstract: BACKGROUND
  Angiosarcomas account for less than 2% of all sarcomas. However, they represent 15% of radiotherapy-induced sarcomas, usually associated to the treatment for breast cancer, cervical cancer, and lymphomas.
  
  
  METHODS
  We report the case of a 56-year-old patient who developed a soft tissue angiosarcoma in the right groin 25 years after receiving radiotherapy for vulvar cancer. To our knowledge, this is the second case reported of a soft tissue angiosarcoma after radiotherapy for a vulvar cancer.
  
  
  CONCLUSIONS
  Postradiation sarcoma must be considered in patients with a history of a previous tumor when a soft tissue mass is seen in the previously irradiated field, especially if the latent period is more than 3 or 5 years. The correct histologic interpretation of such lesions is important because it may result in early identification of the secondary malignancy and may contribute to better management and improved prognosis.
authors.affiliation: Gynecology Department, Hospital La Paz, Madrid, Spain.
authors.forename: Clara
authors.initials: C
authors.lastname: Sanz
authors.forename: Fernando
authors.initials: F
authors.lastname: Moreno
authors.forename: Alvaro
authors.initials: A
authors.lastname: Armas
authors.forename: Antonio
authors.initials: A
authors.lastname: Casado
authors.forename: M C
authors.initials: MC
authors.lastname: Castillo
mesh_terms: D005260:Female; D006119:Groin; D006394:Hemangiosarcoma / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects; D014846:Vulvar Neoplasms / Q000532:radiotherapy*