title: Recent advances in mass spectrometric measurement of dioxins.
abstract: Past years, many efforts have been dedicated to the development of alternative analytical methods for the measurement of dioxins in various types of matrices. Polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) are compounds that are present in samples at part-per-billion (ppb) or part-per-trillion (ppt) level. Their measurement requires the use of very sensitive analytical methods. Gas chromatography (GC) coupled to quadrupole ion storage mass spectrometry (QISTMS), fast GC (FGC) coupled to time-of-flight mass spectrometry (TOFMS) and comprehensive two-dimensional gas chromatography (GC x GC) coupled to TOFMS are the more promising tools challenging the reference GC high resolution mass spectrometry (HRMS) based on sector instruments. We report herein some of the advances we achieved in the past years in our laboratory on the development of alternative measurement methods for those compounds.
authors.affiliation: Mass Spectrometry Laboratory, Dioxin Laboratory, University of Liège, Allée de la Chimie 3, Sart-Tilman, B-4000 Liège, Belgium. jf.focant@ulg.ac.be
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Focant
authors.forename: Catherine
authors.initials: C
authors.lastname: Pirard
authors.forename: Gauthier
authors.initials: G
authors.lastname: Eppe
authors.forename: Edwin
authors.initials: E
authors.lastname: De Pauw
mesh_terms: D004147:Dioxins / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*
chemical_list: D004147:Dioxins