Von Willebrand's disease type I as a cause for subvitreal, retinal and subretinal haemorrhages.
BACKGROUND
Young patients with vitreous, retinal and subvitreal haemorrhages without neovascularisation or prior trauma are a diagnostic challenge for the physician. In this case report, a patient is presented who developed unilateral, spontaneous, subvitreal, retinal and subretinal haemorrhages and was diagnosed with von Willebrand's disease.


METHODS
A 33-year-old Caucasian woman presented at our clinic with unilateral subvitreal, retinal and subretinal haemorrhages. The haemorrhages occurred spontaneously without prior trauma, and the patient had no history of prior bleeding complications. Analysis of the coagulation-fibrinolysis system and von Willebrand multimer analysis led to the diagnosis von Willebrand's disease type I.


CONCLUSIONS
Spontaneous subvitreal, retinal and subretinal haemorrhages may be associated with coagulation disorders. Especially in young patients, von Willebrand's disease should be considered as a possible cause.
Herrmann
Wolfgang Artur
WA
University Eye Clinic, University of Regensburg, Franz-Josef-Strauss Allee 11, 93042, Regensburg, Germany. herrmann@eye-regensburg.de
Lohmann
Chris Patrick
CP
Demmler-Hackenberg
Martina
M
Gabel
Veit-Peter
VP
D000328:Adult; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use; D005260:Female; D005451:Fluorescein Angiography; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D012166:Retinal Hemorrhage / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014823:Vitreous Hemorrhage / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014842:von Willebrand Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
D006490:Hemostatics; D003894:Deamino Arginine Vasopressin