Subglottic tracheal stenosis as primary manifestation of a marginal zone B-cell lymphoma of the larynx.
BACKGROUND
More than 90% of laryngeal tumors are squamous cell carcinomas. Primary hematopoetic neoplasms of the larynx are rare, being mainly extramedullary plasmocytoma and non-Hodgkin's lymphoma (NHL). These are mainly located in the supraglottic and glottic area, with only a few reported in the subglottic region.


METHODS
We report on a 58-year-old man, who presented at our clinic with severe dyspnea. On microlaryngoscopy, a subglottic stenosis at the level of the cricoid cartilage was found. The biopsy revealed the diagnosis of a MALT-type lymphoma (marginal zone B-cell lymphoma). The tracheostomy was followed by locoregional radiotherapy.


CONCLUSIONS
This is the first report of a subglottic MALT-type lymphoma causing a tracheal stenosis. The preferred treatment is locoregional radiotherapy including the draining lymph nodes.
Andratschke
Michaela
M
Department of Otorhinolaryngology, Ludwig-Maximilians-University of Munich, Germany. Michaela.Andratschke@med.uni-muenchen.de
Stelter
Klaus
K
Ihrler
Stephan
S
Hagedorn
Hjalmar
H
D001706:Biopsy; D003251:Constriction, Pathologic / Q000209:etiology; D004417:Dyspnea; D005931:Glottis; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D007828:Laryngoscopy; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D014135:Tracheal Stenosis / Q000209:etiology*; D016896:Treatment Outcome