[Nitric oxide in physiology and pathology of metabolism].
Adipose tissue generates many bioactive substances, which may exert autocrine, paracrine and endocrine effects. Recent studies have revealed, that one of these substances is nitric oxide. There are observed increased expressions of synthases NO (eNOS and iNOS) in adipose tissue in obesity. It seems that these increased expression NOS is reflected by increased serum concentration of NO in obese subjects. The review of the current literature on role of nitric oxide in physiology and pathology metabolism is presented in this paper.
Olszanecka-Glinianowicz
Magdalena
M
Katedra Patofizjologii Slaskiej Akademii Medycznej w Katowicach. magols@esculap.pl
Zahorska-Markiewicz
Barbara
B
Zurakowski
Aleksander
A
Glinianowicz
Mariusz
M
D000273:Adipose Tissue / Q000378:metabolism*; D006801:Humans; D009569:Nitric Oxide / Q000097:blood*; D019001:Nitric Oxide Synthase / Q000378:metabolism; D052247:Nitric Oxide Synthase Type II; D052250:Nitric Oxide Synthase Type III; D009765:Obesity / Q000097:blood*; D015854:Up-Regulation
D009569:Nitric Oxide; C496319:NOS2 protein, human; C496314:NOS3 protein, human; D019001:Nitric Oxide Synthase; D052247:Nitric Oxide Synthase Type II; D052250:Nitric Oxide Synthase Type III