title: Recurrent pulmonary embolism and pulmonary hypertension in chronic tetraplegia.
abstract: METHODS
  Case report.
  
  
  OBJECTIVE
  To describe an unusual case of progressive pulmonary hypertension due to recurrent pulmonary embolism in a chronically paralyzed spinal cord injury patient.
  
  
  METHODS
  Veterans Administration Hospital, West Roxbury, MA, USA.
  
  
  METHODS
  A 57-year-old man, tetraplegic, sensory incomplete and motor complete for 30 years due to a diving accident, complained of lightheadedness and shortness of breath intermittently for 7 years. Examination during the latest episode revealed anxiety, confusion, respirations 28 per min, blood pressure 80/60 mmHg, and arterial pH 7.41, P(CO2) 28 mmHg, P(O2) 95 mmHg on 2 l of oxygen. A chest film 2 weeks earlier had revealed a right-sided cutoff of pulmonary vasculature; the current film showed right-sided pleural effusion. Review of EKGs showed a trend of increasing right axis deviation with recovery and recurrences during the previous 9 years and a current incomplete right bundle branch block with clockwise rotation and inverted T waves in V1-4. Computerized tomography with contrast material revealed small pulmonary emboli, but only in retrospect. The patient died shortly after scanning.
  The pulmonary arteries were free of thromboemboli on gross examination but medium and small-sized arteries were constricted or obliterated with thrombotic material microscopically. The estimated ages of the thromboemboli ranged from days to years. The right ventricle was hypertrophied; the coronary arteries were patent.
  
  
  CONCLUSIONS
  Recurrent pulmonary emboli resulted in chronic pulmonary hypertension and eventual death in a patient with chronic tetraplegia.
authors.affiliation: Spinal Cord Injury Service, Department of Medical Affairs Medical Center, West Roxbury, MA 02492, USA.
authors.forename: J H
authors.initials: JH
authors.lastname: Frisbie
authors.forename: G V R K
authors.initials: GV
authors.lastname: Sharma
authors.forename: P
authors.initials: P
authors.lastname: Brahma
authors.forename: M J
authors.initials: MJ
authors.lastname: Hess
authors.forename: J A
authors.initials: JA
authors.lastname: Hayes
mesh_terms: D002908:Chronic Disease; D004562:Electrocardiography / Q000379:methods; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D011782:Quadriplegia / Q000150:complications*; D011859:Radiography; D012008:Recurrence