title: [Ovarian tumours--accuracy of frozen section diagnosis].
abstract: A retrospective study of 450 ovarian biopsy results were examined for the period of 1998 till 2004 to evaluate the accuracy of frozen section diagnosis. In addition to this we performed a review of the literature for all previous studies in this field in order to study the accuracy rates of the different clinics throughout the world. The histhopathological results of the frozen section diagnosis were equal with the diagnosis of the paraffin blocks in 90%. The sensitivity rates for benign, malignant and borderline tumours, were 96%, 84% and 60% respectively. We had 10 patients (2,1%) false-positive results (overdiagnosed) and 26 (5,2%) false-negative results (underdiagnosed) in frozen section examinations. Frozen section examination of mucinous tumours showed hogher underdiagnosis--18%. The review of the literature showed that there is no significant difference in accuracy rates of frozen section diagnosis for benign and malignant ovarian tumours in relation with time. We found low accuracy rates for borderline tumours which was similar with most of the foreign publications. However the accuracy of the frozen section diagnosis is bettering with the time. As a result of this we conclude that the accuracy rates of the frozen section diagnosis for evaluation of the malignant and benign tumours is quite enough for correct diagnosis. Since accuracy rates for borderline ovarian tumours are low we have to take care and attention of improvement in this field.
authors.forename: S
authors.initials: S
authors.lastname: Ivanov
authors.forename: S
authors.initials: S
authors.lastname: Ivanov
authors.forename: N
authors.initials: N
authors.lastname: Khadzhiolov
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D002031:Bulgaria; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D005629:Frozen Sections / Q000706:statistics & numerical data*; D006801:Humans; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D016612:Paraffin Embedding; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013997:Time Factors