title: A novel and efficient method for cleavage of phenacylesters by magnesium reduction with acetic acid.
abstract: [reaction: see text] In the present study, we use magnesium turnings as a new deprotection reagent for the phenacyl group during orthogonal organic synthesis in the presence of other esters and sensitive protecting groups. By applying the new magnesium turnings/acetic acid deprotection method, phenacyl group can be more easily combined with other protecting groups that are not compatible with the zinc/acetic acid method.
authors.affiliation: Laboratory of Organic Chemistry, Chemistry Department, University of Athens, 15771 Greece.
authors.forename: Stella
authors.initials: S
authors.lastname: Kokinaki
authors.forename: Leondios
authors.initials: L
authors.lastname: Leondiadis
authors.forename: Nikolas
authors.initials: N
authors.lastname: Ferderigos