title: Acrokeratosis paraneoplastica: Bazex syndrome.
abstract: Bazex syndrome is a paraneoplastic dermatosis characterized by acral psoriasiform lesions associated with an underlying neoplasm. We present the case of a 64-year-old patient that was diagnosed with squamous cell lung carcinoma after being evaluated for lesions compatible with paraneoplastic acrokeratosis. With a high frequency Bazex syndrome is the earliest marker of an underlying subclinical neoplasm. An early suspicion is of the outmost importance in order to perform a prompt diagnosis of an underlying malignancy. We propose a diagnostic algorithm upon suspicion of acrokeratosis paraneoplastica and review the pathogenesis of this entity.
authors.affiliation: Hospital Gregorio Marañón, C/Doctor Esquerdo, 46, 28007 Madrid, Spain. martavaldivielso@aedv.es
authors.forename: M
authors.initials: M
authors.lastname: Valdivielso
authors.forename: I
authors.initials: I
authors.lastname: Longo
authors.forename: R
authors.initials: R
authors.lastname: Suárez
authors.forename: M
authors.initials: M
authors.lastname: Huerta
authors.forename: P
authors.initials: P
authors.lastname: Lázaro
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000150:complications*; D006801:Humans; D007642:Keratosis / Q000175:diagnosis / Q000473:pathology*; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000473:pathology*; D013577:Syndrome