title: Pneumomediastinum due to intractable hiccup as the presenting symptom of multiple sclerosis.
abstract: Pneumomediastinum and subcutaneous emphysema generally occurs following trauma to the esophagus or lung. It also occurs spontaneously in such situations of elevating intra-thoracic pressure as asthma, excessive coughing or forceful straining. We report here on the rare case of a man who experienced the signs of pneumomediastinum and subcutaneous emphysema after a prolonged bout of intractable hiccup as the initial presenting symptoms of multiple sclerosis.
authors.affiliation: Department of Neurology, Yongdong Severance Hospital, Yonsei University College of Medicine, 146-92 Dogok-dong, Kangnam-gu, Seoul 135-720, Korea.
authors.forename: Sang-Jun
authors.initials: SJ
authors.lastname: Na
authors.forename: Sang In
authors.initials: SI
authors.lastname: Lee
authors.forename: Tae-Sub
authors.initials: TS
authors.lastname: Chung
authors.forename: Young-Chul
authors.initials: YC
authors.lastname: Choi
authors.forename: Kyung-Yul
authors.initials: KY
authors.lastname: Lee
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D006606:Hiccup / Q000150:complications* / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008478:Mediastinal Emphysema / Q000000981:diagnostic imaging / Q000209:etiology*; D009103:Multiple Sclerosis / Q000150:complications* / Q000175:diagnosis; D013352:Subcutaneous Emphysema / Q000209:etiology; D013904:Thoracic Vertebrae / Q000473:pathology; D014057:Tomography, X-Ray Computed