Laccase expression in murine pulmonary Cryptococcus neoformans infection.
Cryptococcus neoformans laccase expression during murine infection was investigated in lung tissue by immunohistochemistry and immunogold electron microscopy. Laccase was detected in the fungal cell cytoplasm, cell wall, and capsule in vivo. The amount of laccase found in different sites varied as a function of the time of infection.
Garcia-Rivera
Javier
J
Division of Infectious Disease, Albert Einstein College of Medicine, 1300 Morris Park Ave., Golding 701, Bronx, NY 10461, USA.
Tucker
Stephanie C
SC
Feldmesser
Marta
M
Williamson
Peter R
PR
Casadevall
Arturo
A
D000818:Animals; D003453:Cryptococcosis / Q000382:microbiology*; D003455:Cryptococcus neoformans / Q000201:enzymology* / Q000472:pathogenicity / Q000648:ultrastructure*; D007150:Immunohistochemistry; D042845:Laccase / Q000378:metabolism*; D008168:Lung / Q000382:microbiology; D008172:Lung Diseases, Fungal / Q000382:microbiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008854:Microscopy, Electron; D014774:Virulence
D042845:Laccase