Clozapine-induced tardive dyskinesia: a case report.
OBJECTIVE
Clozapine is indicated in the treatment of patients with tardive dyskinesia. However, there have been some reports of movement disorders associated with clozapine treatment in the literature. The authors report a patient who developed tardive dyskinesia 1 year after initiation of clozapine treatment.


METHODS
The patient was a 65-year-old male with diagnosis of schizophrenia who had used multiple typical and atypical antipsychotics for 30 years. Clozapine treatment was initiated for his resistant symptoms. He developed buccolingual dyskinesia of moderate severity, which started 1 year after the initiation of clozapine treatment and did not ameliorate during follow-up.


CONCLUSIONS
This case may contribute to existing knowledge by raising the possibility that clozapine can induce dyskinesia.
Ertugrul
Aygun
A
Department of Psychiatry, Hacettepe University Faculty of Medicine, Ankara 06100, Turkey. aertugru@hacettepe.edu.tr
Demir
Basaran
B
D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003024:Clozapine / Q000009:adverse effects* / Q000627:therapeutic use; D004409:Dyskinesia, Drug-Induced / Q000503:physiopathology*; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy; D012565:Schizophrenic Psychology
D014150:Antipsychotic Agents; D003024:Clozapine