title: [A case with advanced carcinoma of the gallbladder responding to UFT monotherapy].
abstract: Gallbladder carcinoma is a fatal disease with highly metastatic potential, and the chemotherapeutic regimen has not been established yet. We reported here a case of gallbladder carcinoma with lung and liver meatstases responding to a single agent, UFT. A 70-year-old female with advanced carcinoma of the gallbladder and bilateral pulmonary metastases were treated with UFT 600 mg/day weekday for half a year. Pulmonary metastases disappeared completely, and the primary lesion shrank markedly 6 months after. Unfortunately, the patient died 1.5 years after the start of treatment due to relapse of liver and lung lesions.
authors.affiliation: Dept of Surgery, Health Insurance Hitoyoshi General Hospital.
authors.forename: Masami
authors.initials: M
authors.lastname: Kimura
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Inoue
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Morisaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kaneda
authors.forename: Shuichi
authors.initials: S
authors.lastname: Kume
authors.forename: Hiroo
authors.initials: H
authors.lastname: Matsushita
authors.forename: Kei
authors.initials: K
authors.lastname: Horino
authors.forename: Takumasa
authors.initials: T
authors.lastname: Nishimura
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Arima
authors.forename: Kuninori
authors.initials: K
authors.lastname: Uemura
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000188:drug therapy* / Q000556:secondary; D000284:Administration, Oral; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D005706:Gallbladder Neoplasms / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary; D011788:Quality of Life; D005641:Tegafur / Q000627:therapeutic use*; D014498:Uracil / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D004338:Drug Combinations; C096910:UFT(R) drug; D005641:Tegafur; D014498:Uracil