title: A desymmetrization route to fused Troger's base analogues: synthesis, isolation, and characterization of the first anti-anti diastereomer of a fused tris-Troger's base analogue.
abstract: A desymmetrization route to fused Troger's base analogues was developed. In this way, the synthesis of the first example of an anti-anti diastereomer of a fused tris-Troger's base analogue was accomplished. The resulting compound 5b is a nonlinear symmetric regioisomer obtained from p-bromoaniline in 7% yield. The corresponding syn-anti diastereomer 5a was obtained in 4% yield.
authors.affiliation: Organic Chemistry, Department of Chemistry, Lund University, Sweden.
authors.forename: Anna
authors.initials: A
authors.lastname: Hansson
authors.forename: Torbjörn
authors.initials: T
authors.lastname: Wixe
authors.forename: Karl-Erik
authors.initials: KE
authors.lastname: Bergquist
authors.forename: Kenneth
authors.initials: K
authors.lastname: Wärnmark