[Sensorineural hearing loss in LEOPARD syndrome].
The rare multiple lentigines (LEOPARD) syndrome represents a complex of skin, cardiac, skeletal, inner ear and other malformations. There is marked variability in expression of the syndrome. We report on a 20 year old man, showing typical lentiginosis, a retardation of growth, tachycardiac conduction abnormality, ophthalmologic manifestations and a sensorineural hearing loss. Pathogenesis, clinical and differential diagnostic aspects are discussed in this case report. The early diagnosis of a senosorineural hearing loss is useful in order to provide appropriate rehabilitation. When lentiginosis is diagnosed, it is important to consider further abnormalities such as cardiomyopathy, which can be associated with a high mortality.
Schrom
T
T
Klinik für Hals-, Nasen-, Ohrenkrankheiten, Universitätsmedizin Berlin, Charité Campus Mitte, Berlin, Germany. thomas.schrom@gmx.de
Habermann
A
A
Scherer
H
H
D000328:Adult; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000534:rehabilitation*; D006801:Humans; D044542:LEOPARD Syndrome / Q000175:diagnosis* / Q000534:rehabilitation*; D008297:Male