title: Efficiency is a legitimate consideration in equitable distribution of cadaveric transplants: development of an efficiency-equality model of equity.
abstract: It is proposed that equity is a trade-off, or compromise, between equality and efficiency. The kidney transplant allocation algorithm currently used in the United Kingdom (NAT) was tested in the efficiency-equity model. In an exercise of 2000 past UK donors and a dynamic waiting list of 5000 potential recipients, 4000 transplants were allocated according either by NAT, by equal allocation (EQ) (a lottery), or by efficiency (EF). Diabetic recipients received 7.4% of transplants in NAT, 8.6% in EQ, and 0% in EF; paediatric recipients received 6.8% in NAT, 0.6% in EQ, and 0.7% in EF model. For HLA matching, there were 77.9% favourable or 000 matches in NAT, 3.0% in EQ, and 53.1% in EF. Predicted survival showed better outcomes in EF versus NAT (P < .0001) and in NAT versus EQ (P = .05). The NAT allocation system favours paediatric recipients and does not deny diabetics the chance of a transplant, broadly in line with published public and professional opinions. The NAT scheme achieves better HLA matching than the EF model, and this suggests that the rationale for allocation based primarily on HLA matching could be reexamined.
authors.affiliation: Renal Transplant Unit, University Hospitals Coventry and Warwickshire, Coventry, United Kingdom. robert.higgins@uhcw.nhs.uk
authors.forename: R M
authors.initials: RM
authors.lastname: Higgins
authors.forename: R
authors.initials: R
authors.lastname: Johnson
authors.forename: M N A
authors.initials: MN
authors.lastname: Jones
authors.forename: C
authors.initials: C
authors.lastname: Rudge
mesh_terms: D000465:Algorithms; D002102:Cadaver; D002648:Child; D004526:Efficiency; D006650:Histocompatibility Testing; D006801:Humans; D008954:Models, Biological; D018579:Patient Selection; D040841:Resource Allocation / Q000458:organization & administration*; D013997:Time Factors; D014019:Tissue Donors; D009927:Tissue and Organ Procurement / Q000379:methods*; D006113:United Kingdom; D014850:Waiting Lists