title: Pectenotoxin-2 synthetic studies. 2. Construction and conjoining of ABC and DE Eastern hemisphere subtargets.
abstract: [reaction: see text] Practical asymmetric synthesis of aldehyde 2 and tetrazolyl sulfone 3 has allowed for their coupling via Julia olefination to generate 32 as a single product. This substance possesses the entire carbon backbone of the A-E substructure of pectenotoxin-2.
authors.affiliation: Evans Chemical Laboratories, The Ohio State University, Columbus, Ohio 43210, USA.
authors.forename: Dmitriy
authors.initials: D
authors.lastname: Bondar
authors.forename: Jian
authors.initials: J
authors.lastname: Liu
authors.forename: Thomas
authors.initials: T
authors.lastname: Müller
authors.forename: Leo A
authors.initials: LA
authors.lastname: Paquette
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis*; D002384:Catalysis; D005663:Furans / Q000138:chemical synthesis*; D018942:Macrolides; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011714:Pyrans / Q000138:chemical synthesis*; D000095702:Polyether Toxins
chemical_list: D001688:Biological Products; D005663:Furans; D018942:Macrolides; D011714:Pyrans; C098380:pectenotoxin 2; D000095702:Polyether Toxins