title: Tibial nerve SEPs localized the lesion site in a patient with early tabes dorsalis.
abstract: There is controversy regarding the initial pathology of tabes dorsalis. In a patient with early tabes dorsalis, tibial nerve somatosensory evoked potentials elicited normal P15, a delayed traveling peak in the lumbar bipolar leads, and absent subsequent components. Based on the comparison with normative data and stimulation at different intensities, the authors conclude that only the slower conducting antidromic motor volleys are preserved, whereas the dorsal root is damaged at its distal end.
authors.affiliation: Department of Neurology, Teikyo University School of Medicine, Tokyo, Japan. sonoom@med.teikyo-u.ac.jp
authors.forename: M
authors.initials: M
authors.lastname: Sonoo
authors.forename: A
authors.initials: A
authors.lastname: Katayama
authors.forename: T
authors.initials: T
authors.lastname: Miura
authors.forename: T
authors.initials: T
authors.lastname: Shimizu
authors.forename: K
authors.initials: K
authors.lastname: Inoue
mesh_terms: D000328:Adult; D018450:Disease Progression; D004558:Electric Stimulation; D004568:Electrodiagnosis; D005071:Evoked Potentials; D005073:Evoked Potentials, Somatosensory / Q000502:physiology; D020233:Gait Disorders, Neurologic / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D005727:Ganglia, Spinal / Q000503:physiopathology; D006801:Humans; D008297:Male; D009431:Neural Conduction / Q000502:physiology; D009437:Neuralgia / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D009475:Neurons, Afferent / Q000502:physiology; D010400:Penicillin G / Q000627:therapeutic use; D011930:Reaction Time / Q000502:physiology; D020127:Recovery of Function; D012021:Reflex, Abnormal / Q000502:physiology; D012678:Sensation Disorders / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D020886:Somatosensory Disorders / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D013126:Spinal Nerve Roots / Q000503:physiopathology*; D013606:Tabes Dorsalis / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology*; D013979:Tibial Nerve / Q000503:physiopathology*; D016896:Treatment Outcome
chemical_list: D010400:Penicillin G