title: Laparoscopic donor nephrectomy yields kidneys with structure and function equivalent to those retrieved by open surgery.
abstract: The technical challenges of laparosopcic transperitoneal donor nephrectomy (LapDN) have raised concerns over the quality of the procured allografts. This study reports the anatomical and functional outcomes of kidneys retrieved from 60 live donors entered into a randomized controlled trial of open versus laparoscopic procurement. Open and laparoscopic donors were well matched for age (P = .18) and body mass index (P = .49). Operating time (P = .0001) and first warm ischaemic time (P < .001) were longer for the laparoscopic donors but total warm time was not different (P = .52). Left renal vein length (P = .14) and left renal artery length (P = .38) were similar. No differences in right vessel length were observed. Rates of acute rejection did not differ, and recipient renal function was similar in the two groups. This study demonstrates that LapDN yields kidneys that are structurally and functionally equivalent to those acquired by the open operation. This data may go some way towards allaying concerns over the effect of laparoscopic procurement on live donor kidneys.
authors.affiliation: University of Leicester, Leicester, UK. nicholasbrook@fastmail.com
authors.forename: N R
authors.initials: NR
authors.lastname: Brook
authors.forename: S J
authors.initials: SJ
authors.lastname: Harper
authors.forename: A
authors.initials: A
authors.lastname: Bagul
authors.forename: R
authors.initials: R
authors.lastname: Elwell
authors.forename: M L
authors.initials: ML
authors.lastname: Nicholson
mesh_terms: D005260:Female; D006801:Humans; D007668:Kidney; D010535:Laparoscopy / Q000379:methods / Q000592:standards*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods / Q000592:standards*; D012449:Safety; D020858:Tissue and Organ Harvesting / Q000379:methods / Q000592:standards*; D016896:Treatment Outcome