Memory of chirality in intramolecular conjugate addition of enolates: a novel access to nitrogen heterocycles with contiguous quaternary and tertiary stereocenters.
Nitrogen heterocycles with contiguous quaternary and tertiary stereocenters have been prepared in high enantiomeric purity by intramolecular conjugate addition of enolates generated from alpha-amino acid derivatives via memory of chirality.
Kawabata
Takeo
T
Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan. kawabata@scl.kyoto-u.ac.jp
Majumdar
Swapan
S
Tsubaki
Kazunori
K
Monguchi
Daiki
D