[A case with advanced carcinoma of the gallbladder responding to UFT monotherapy].
Gallbladder carcinoma is a fatal disease with highly metastatic potential, and the chemotherapeutic regimen has not been established yet. We reported here a case of gallbladder carcinoma with lung and liver meatstases responding to a single agent, UFT. A 70-year-old female with advanced carcinoma of the gallbladder and bilateral pulmonary metastases were treated with UFT 600 mg/day weekday for half a year. Pulmonary metastases disappeared completely, and the primary lesion shrank markedly 6 months after. Unfortunately, the patient died 1.5 years after the start of treatment due to relapse of liver and lung lesions.
Kimura
Masami
M
Dept of Surgery, Health Insurance Hitoyoshi General Hospital.
Inoue
Mitsuhiro
M
Morisaki
Tetsuro
T
Kaneda
Hiroshi
H
Kume
Shuichi
S
Matsushita
Hiroo
H
Horino
Kei
K
Nishimura
Takumasa
T
Arima
Toshiharu
T
Uemura
Kuninori
K
D000231:Adenocarcinoma, Papillary / Q000188:drug therapy* / Q000556:secondary; D000284:Administration, Oral; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D005706:Gallbladder Neoplasms / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary; D011788:Quality of Life; D005641:Tegafur / Q000627:therapeutic use*; D014498:Uracil / Q000627:therapeutic use*
D000970:Antineoplastic Agents; D004338:Drug Combinations; C096910:UFT(R) drug; D005641:Tegafur; D014498:Uracil