Optical coherence tomography in presumed congenital simple hamartoma of retinal pigment epithelium.
OBJECTIVE
To report the optical coherence tomography (OCT) findings in two cases of presumed congenital simple retinal pigment epithelial (RPE) hamartoma.


METHODS
Observational case report.


METHODS
Fundus examination, fluorescein angiography, ultrasonography, and OCT were done on two cases of simple RPE hamartoma.


RESULTS
A heavily pigmented solitary macular lesion was noted in the right eye of a 22-year-old man and a 55-year-old woman. The young man had a foveal lesion and a vision of 10/200; the woman with eccentric lesion had a vision of 20/20. The lesions blocked fluorescence on angiogram; sonography showed hyper-reflective nodules. OCT demonstrated full-thickness retinal replacement, complete optical shadowing, and abrupt margins of the lesion in both the cases, and vitreomacular adhesion at the temporal margin of the foveal lesion.


CONCLUSIONS
Congenital simple RPE hamartoma may rarely occur at the foveal center, resulting in poor visual acuity. OCT is a useful non-invasive adjunct for diagnosis of this rare tumor and may reveal additional features like vitreoretinal adhesion.
Shukla
Dhananjay
D
Retina-Vitreous Service, Aravind Eye Hospital & Postgraduate Institute of Ophthalmology, 1 Anna Nagar, Madurai 625-020, Tamil Nadu, India. daksh@aravind.org
Ambatkar
Shamik
S
Jethani
Jitendra
J
Kim
Ramasamy
R
D000328:Adult; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005451:Fluorescein Angiography; D006222:Hamartoma / Q000151:congenital / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012164:Retinal Diseases / Q000151:congenital / Q000175:diagnosis*; D041623:Tomography, Optical Coherence