[Myasthenia gravis and pregnancy].
We retrospectively analyzed the course and outcome of pregnancy in a group of 26 women with myasthenia gravis. Premature births were noted in 7.9% of pregnancies, the rate of cesarean section was 15.8%. Neonatal myasthenia was observed in 10 children born by 5 women (16% of the mothers). There were three neonatal deaths: two due to neonatal myasthenia, one in a child born with multiple congenital anomalies. Transient exacerbation of MG symptoms was observed during four pregnancies (10.5%). MG is not associated with increased risk for MG patient and the newborn. Giving birth to one child with transient MG increases the risk of transient MG in consecutive pregnancies.
Kostera-Pruszczyk
Anna
A
Klinika Neurologii AM w Warszawie. akostera@amwaw.edu.pl
Emeryk-Szajewska
Barbara
B
D000328:Adult; D002585:Cesarean Section / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008499:Medical Records; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000453:epidemiology*; D020941:Myasthenia Gravis, Neonatal / Q000453:epidemiology; D007752:Obstetric Labor, Premature / Q000453:epidemiology; D011044:Poland / Q000453:epidemiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000453:epidemiology*; D011256:Pregnancy Outcome / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors