title: Fibrin sealant treatment of splenic injuries during oesophagectomy.
abstract: The incidence of 'accidental' splenectomy during oesophagectomy varies from 4 to 42% and leads to an increase in sepsis, anastomotic leakage and mortality. Therefore, preservation of the spleen should be the aim of treatment whenever splenic injury occurs. We describe the use of fibrin glue delivered as a thin film by a spray applicator for rapid and definitive haemostasis of grades 1 and 2 splenic injuries in patients undergoing oesophagectomy.
authors.affiliation: Department of Cardiothoracic Surgery, Derriford Hospital, Plymouth PL6 8DH, UK. paulmodi@doctors.org.uk
authors.forename: Paul
authors.initials: P
authors.lastname: Modi
authors.forename: Joseph
authors.initials: J
authors.lastname: Rahamim
mesh_terms: D016629:Esophagectomy / Q000009:adverse effects*; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006488:Hemostasis, Surgical / Q000379:methods; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D007431:Intraoperative Complications / Q000628:therapy; D013154:Spleen / Q000293:injuries*; D014014:Tissue Adhesives / Q000627:therapeutic use*
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives