[Usefulness of 2 coproparasitological methods and their utilization in an antigiardiasis therapeutic trial].
A study of 456 children aged 1-5 from 4 day care centers of San Miguel del Padron municipality was conducted in 1998, to evaluate the diagnosis of Giardia lamblia and other intestinal protozoa by using comparatively the coproparasitological diagnostic methods of direct examination and Ritchie's concentration technique or formol-ether. Besides, a therapeutical trial was developed with tinidazole and albendazole for treating the infection caused by G lamblia. Ritchie's concentration technique was more effective than the microscopic direct examination for diagnosing Giardia lamblia, Entamoeba histolytical/Entamoeba dispar and Cyclospora cayetanensis. It was demonstratyed that the serial examination was more sensitive than the analysis of just one sample (p< 0.01). On the other hand, tinidazole proved to be more efficient than albendazole to treat the infection produced by G. lamblia, with a greater cure percentage (72 % vs. 334.6%), (p < 0.01).
Mendoza
Daimary
D
Instituto de Medicina Tropical "Pedro Kouri", Ciudad de La Habana, Cuba. ciipk@ipk.sld.cu
Núñez
Fidel Angel
FA
Escobedo
Angel Arturo
AA
Pelayo
Liliana
L
Fernández
Maribel
M
Torres
Dinorah
D
Cordovi
Raúl A
RA
D015766:Albendazole / Q000627:therapeutic use*; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D019411:Clinical Laboratory Techniques; D005243:Feces / Q000469:parasitology*; D005873:Giardiasis / Q000188:drug therapy* / Q000469:parasitology*; D006801:Humans; D007223:Infant; D010274:Parasitology / Q000379:methods; D014011:Tinidazole / Q000627:therapeutic use*
D000981:Antiprotozoal Agents; D014011:Tinidazole; D015766:Albendazole