[Genetics of the cell cycle: adaptive modification of the cycB2g mutation expression in dividing cells of Drosophila melanogaster].
The effect of mutation CycB2g on mitosis in neural ganglia and imaginal disks was studied in third-instar larvae of Drosophila melanogaster. Chromosome condensation and segregation were shown to be impaired in dividing cells of mutant larvae. During the three-year period of maintenance of the mutation in heterozygote, frequencies of some defects decreased via cellular adaptive modification.
Lebedeva
L I
LI
Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibisrsk, 630090 Russia. lil@bionet.nsc.ru
Trunova
S A
SA
Omelyanchuk
L V
LV
D000818:Animals; D020090:Chromosome Segregation / Q000235:genetics* / Q000502:physiology; D019926:Cyclin B / Q000235:genetics* / Q000378:metabolism; D029721:Drosophila Proteins / Q000235:genetics* / Q000378:metabolism; D004331:Drosophila melanogaster; D005724:Ganglia / Q000166:cytology / Q000502:physiology; D006579:Heterozygote; D009154:Mutation / Q000235:genetics*
C503698:CycB protein, Drosophila; D019926:Cyclin B; D029721:Drosophila Proteins