title: [Upper extremity gangrene in an infant of a diabetic mother, presenting at birth].
abstract: In utero gangrene of an extremity because of an arterial thrombosis is rare. More than 20% of the reported cases concern infants of diabetic mothers (IDM) with poor control of diabetes. Changes in coagulation related to deviation of clotting factors and low plasminogen activity may be the cause. We report a case of an IDM who presented at birth with upper extremity gangrene. The Dopplersonography has shown missing pulsations and thrombosis of a. brachialis sin, which was confirmed after amputation of the arm on the 5th day. The postoperative period was complicated by septicaemia, necrotising enterocolitis and disseminated intravasal coagulation resulting in the baby's death 10 days after birth.
authors.forename: L
authors.initials: L
authors.lastname: Vakrilova
authors.forename: A
authors.initials: A
authors.lastname: Popivanova
authors.forename: Z
authors.initials: Z
authors.lastname: Emilova
authors.forename: B
authors.initials: B
authors.lastname: Slŭncheva
authors.forename: R
authors.initials: R
authors.lastname: Shishkova
mesh_terms: D000328:Adult; D000671:Amputation, Surgical; D001132:Arm / Q000473:pathology* / Q000601:surgery; D020345:Enterocolitis, Necrotizing / Q000150:complications / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D005734:Gangrene / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D007511:Ischemia / Q000209:etiology / Q000473:pathology; D011184:Postoperative Period; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000150:complications*; D018805:Sepsis / Q000150:complications / Q000473:pathology; D013927:Thrombosis / Q000209:etiology / Q000473:pathology