[Antioxidant status of patients with primary colorectal cancer and liver metastases of colorectal cancer].
In the present work we examined selected parameters of antioxidant status in patients with primary colorectal cancer and liver metastasis of colorectal cancer. Total antioxidant status (TAS), activity of superoxide dismutase (SOD) and catalase (CAT) were examined in colorectal primary cancer, liver metastasis of colorectal cancer and in blood serum of patients before and after surgery. It was found that patients have disordered function of the the antioxidant system. This is demonstrated by decreased TAS and changes in the activity of SOD and CAT, both in tumor tissue and blood serum.
Czeczot
Hanna
H
Katedra i Zakfad Biochemii Akademii Medycznej w Warszawie.
Skrzycki
Michał
M
Podsiad
Małgorzata
M
Gawryszewska
Ewelina
E
Nyckowski
Paweł
P
Porembska
Zofia
Z
D000230:Adenocarcinoma / Q000097:blood / Q000201:enzymology / Q000378:metabolism* / Q000556:secondary; D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000378:metabolism*; D016022:Case-Control Studies; D002374:Catalase / Q000097:blood / Q000378:metabolism*; D015179:Colorectal Neoplasms / Q000097:blood / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000097:blood / Q000201:enzymology / Q000378:metabolism* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D013482:Superoxide Dismutase / Q000097:blood / Q000378:metabolism*
D000975:Antioxidants; D002374:Catalase; D013482:Superoxide Dismutase