[Risks factors for the development of diabetes in women with history of gestational diabetes mellitus].
Women who suffered from impaired carbohydrate metabolism during pregnancy are more likely to develop different types of diabetes later in their lives. The aim of this paper was to study the risk factors for the development of diabetes in group of women with gestational diabetes mellitus (GDM) in anamnesis.


METHODS
200 women took part in this study, who had gestational diabetes diagnosed between 1980-1998. All women were divided into 4 groups depending on the type of disorders occurring at the moment of examination: DM1 - women diagnosed with type I diabetes, DM2 - women diagnosed with type 2 diabetes, IGT-women with glucose levels in OGTT, which applied to impaired glucose tolerance (acc. to WHO criteria), NDM - women with no clinical signs of diabetes, with normal result of OGTT.


RESULTS
The risk of diabetes development is significantly higher (independently of the clinical type) in women who had had GDM include: high glucose levels at the time of GDM diagnosis, early onset of symptoms - related to weeks of gestation, and the insulin treatment during pregnancy. However multifactor analysis indicates that the only significant risk factors for DM 1 are early onset of diabetes during pregnancy and high glucose levels 2 hours after OGTT during pregnancy (p < 0.05). High levels of glucose 2 hours after OGTT and high Body Mass Index (BMI) turned out to be the independent risk factors of diabetes type 2 (p < 0.05).


CONCLUSIONS
Knowledge of risk factors allows to recognize a diabetes high risk group among women who suffered from diabetes during pregnancy.
Cypryk
Katarzyna
K
Klinika Endokrynologii i Terapii Izotopowej Uniwersytetu Medycznego, Instytut Centrum Zdrowia Matki Polki w łodz. kcypryk@mp.pl
Szymczak
Wiesław
W
Pertyńska-Marczewska
Magdalena
M
Zawodniak-Szałapska
Małgorzata
M
Lewiński
Andrzej
A
D000328:Adult; D016022:Case-Control Studies; D003920:Diabetes Mellitus / Q000209:etiology*; D016640:Diabetes, Gestational / Q000150:complications*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D012307:Risk Factors