Cervical spine and crystal-associated diseases: imaging findings.
The cervical spine may be specifically involved in crystal-associated arthropathies. In this article, we focus on the three common crystals and diseases: hydroxyapatite crystal deposition disease, calcium pyrophosphate dihydrate (CPPD) deposition disease, and monosodium urate crystals (gout). The cervical involvement in crystal-associated diseases may provoke a misleading clinical presentation with acute neck pain, fever, or neurological symptoms. Imaging allows an accurate diagnosis in typical cases with calcific deposits and destructive lesions of the discs and joints. Most of the cases are related to CPPD or hydroxyapatite crystal deposition; gout is much less common.
Feydy
Antoine
A
Service de Radiologie B, Hôpital Cochin, 27, rue du faubourg Saint Jacques, 75679, Paris Cedex 14, France. antoine.feydy@cch.aphp.fr
Lioté
Frédéric
F
Carlier
Robert
R
Chevrot
Alain
A
Drapé
Jean-Luc
JL
D000328:Adult; D002114:Calcinosis / Q000175:diagnosis*; D002131:Calcium Pyrophosphate / Q000032:analysis*; D002358:Cartilage, Articular / Q000473:pathology; D002574:Cervical Vertebrae / Q000473:pathology*; D002648:Child; D002805:Chondrocalcinosis / Q000473:pathology; D003460:Crystallization; D017886:Durapatite / Q000032:analysis*; D005260:Female; D006073:Gout / Q000175:diagnosis*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007403:Intervertebral Disc / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019547:Neck Pain / Q000209:etiology*; D009809:Odontoid Process / Q000473:pathology; D013166:Spondylitis / Q000175:diagnosis* / Q000209:etiology; D013582:Synovial Fluid / Q000737:chemistry; D052256:Tendinopathy / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014527:Uric Acid / Q000032:analysis*
D014527:Uric Acid; D017886:Durapatite; D002131:Calcium Pyrophosphate