Male factor infertility associated with a familial translocation t(1;13)(q24;q10).
We report a case of a family with one sister and one brother in which the brother inherited a t(1;13)(q24;q10) translocation from his mother. We describe a case with a clear translocation between the long arm of chromosome 1 and the long arm of chromosome 13. It is possible that the APOE and MTHFR genotypes and lower folate status may also be responsible for the above mentioned translocation.
Sazci
Ali
A
Department of Medical Biology and Genetics, Faculty of Medicine, University of Kocaeli, Derince, Turkey. alisazci@superonline.com
Ercelen
Nesrin
N
Ergul
Emel
E
Akpinar
Gurler
G
D000328:Adult; D002878:Chromosomes, Human, Pair 1 / Q000235:genetics*; D002882:Chromosomes, Human, Pair 13 / Q000235:genetics*; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D008297:Male; D010375:Pedigree; D014178:Translocation, Genetic / Q000235:genetics*