Echocardiographic examination of atrioventricular and interventricular delay optimization in cardiac resynchronization therapy.
In 21 patients implanted with a biventricular pacing device with programmable interventricular delay (VVd), the myocardial performance index (MPI) was evaluated during spontaneous sinus rhythm, simultaneous biventricular pacing, and sequential biventricular pacing at different VVds and atrioventricular delays (AVds). The AVd-VVd combination associated with the minimum MPI defined patient-tailored biventricular pacing. Simultaneous biventricular pacing significantly improved MPI compared with spontaneous sinus rhythm. An additional improvement was obtained by tailored biventricular pacing. The optimal AVds were significantly shorter during right ventricular preactivation than during left ventricular preactivation.
Porciani
Maria Cristina
MC
Division of Cardiology, Careggi Hospital, Florence, Italy. c.porciani@dac.unifi.it
Dondina
Cristina
C
Macioce
Roberto
R
Demarchi
Gabriele
G
Pieragnoli
Paolo
P
Musilli
Nicola
N
Colella
Andrea
A
Ricciardi
Giuseppe
G
Michelucci
Antonio
A
Padeletti
Luigi
L
D000208:Acute Disease; D000368:Aged; D001283:Atrioventricular Node / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002037:Bundle-Branch Block / Q000000981:diagnostic imaging / Q000628:therapy*; D002304:Cardiac Pacing, Artificial; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D008297:Male; D013599:Systole / Q000502:physiology*; D013997:Time Factors; D016896:Treatment Outcome; D014463:Ultrasonography; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000628:therapy*