Improving small-diameter vascular grafts: from the application of an endothelial cell lining to the construction of a tissue-engineered blood vessel.
One of the main reasons why vascular reconstruction with synthetic small-diameter grafts has limited success is the absence of endothelial cells. To improve the outcome of nonvenous vascular bypass surgery, cell seeding of vascular grafts and other tissue-engineering techniques were developed. In this article, an overview is given of the artificial blood vessel as an alternative for venous vascular bypass surgery.
Heyligers
J M M
JM
Department of Vascular Surgery, University Medical Center, 3508 GA Utrecht, The Netherlands. j.m.m.heyligers@chir.azu.nl
Arts
C H P
CH
Verhagen
H J M
HJ
de Groot
Ph G
PG
Moll
F L
FL
D001777:Blood Coagulation / Q000502:physiology; D001808:Blood Vessels / Q000637:transplantation*; D042783:Endothelial Cells; D006801:Humans; D006965:Hyperplasia / Q000503:physiopathology; D015539:Platelet Activation / Q000502:physiology; D010974:Platelet Aggregation / Q000502:physiology; D013234:Stem Cells; D023822:Tissue Engineering; D017539:Tunica Intima / Q000473:pathology; D014654:Vascular Patency; D014656:Vascular Surgical Procedures