New bisindole alkaloids isolated from Myxomycetes Arcyria cinerea and Lycogala epidendrum.
Two new bisindole alkaloids, named cinereapyrrole A (1) and B (2), were isolated from wild fruit bodies of Arcyria cinerea and three new bisindole alkaloids (3-5) were isolated from wild fruit bodies of Lycogala epidendrum. Seven known bisindoles (6-12) were concomitantly obtained from them. The structures of the new compounds were elucidated by spectral data. Among these bisindole alkaloids, compound 12 showed cytotoxicity against cultured tumor cell lines.
Kamata
Kazuaki
K
Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 263-8522, Japan.
Kiyota
Makiko
M
Naoe
Ayano
A
Nakatani
Satomi
S
Yamamoto
Yukinori
Y
Hayashi
Masahiko
M
Komiyama
Kanki
K
Yamori
Takao
T
Ishibashi
Masami
M
D000818:Animals; D003603:Cytotoxins / Q000737:chemistry / Q000302:isolation & purification; D016837:Dictyosteliida; D006367:HeLa Cells; D006801:Humans; D026121:Indole Alkaloids / Q000737:chemistry* / Q000302:isolation & purification*; D009235:Myxomycetes / Q000737:chemistry* / Q000302:isolation & purification*
D003603:Cytotoxins; D026121:Indole Alkaloids