Palladium-catalyzed intermolecular three-component coupling of aryl iodides, alkynes, and alkenes to produce 1,3-butadiene derivatives.
[reaction: see text] The sequential three-component coupling of aryl iodides, diarylacetylenes, and monosubstituted alkenes effectively proceeds in the presence of Pd(OAc)(2), LiCl, and NaHCO(3) as catalyst, promoter, and base, respectively, in DMF-H(2)O to produce the corresponding 1,3-butadiene derivatives.
Shibata
Kana
K
Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Satoh
Tetsuya
T
Miura
Masahiro
M