Human thrombin for treatment of pseudoaneurysms: comparison of bovine and human thrombin sonogram-guided injection.
OBJECTIVE
The purpose of this research was to review our experience and determine the success rate of percutaneous sonogram-guided human thrombin injection to treat iatrogenic femoral pseudoaneurysms and compare this with the results obtained with bovine thrombin injection.


CONCLUSIONS
In our experience, the use of human thrombin for the treatment of iatrogenic femoral pseudoaneurysms is highly efficient (100%), the administered dose is significantly less than with bovine thrombin, and the risk for allergy is potentially lower. At our hospital, human thrombin has replaced bovine thrombin and is the first line of treatment for an iatrogenic pseudoaneurysm.
Vázquez
Victoria
V
Department of Roentgenology, Hospital Universitario Virgen de la Arrixaca, Ctra. Madrid-Cartagena, El Palmar 30120, Murcia, Spain. vvs63@hotmail.com
Reus
Manuel
M
Piñero
Antonio
A
Abellán
Dolores
D
Canteras
Manuel
M
Espinosa de Rueda
Mariano
M
Morales
Dolores
D
Parrilla
Pascual
P
D000368:Aged; D000704:Analysis of Variance; D017541:Aneurysm, False / Q000000981:diagnostic imaging / Q000188:drug therapy*; D000818:Animals; D002417:Cattle; D016009:Chi-Square Distribution; D003029:Coagulants / Q000627:therapeutic use*; D005260:Female; D005263:Femoral Artery; D006801:Humans; D007049:Iatrogenic Disease; D007267:Injections; D008297:Male; D013917:Thrombin / Q000627:therapeutic use*; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional
D003029:Coagulants; D013917:Thrombin