[Analysis of the treatment of unexpected gallbladder cancer].
OBJECTIVE
To investigate the secondary operation methods and the effects on the prognosis of unexpected gallbladder cancer (UGC).


METHODS
A retrospective analysis on the clinical data was made for 41 patients who underwent extended radical excision from June 1995 to December 2002. Among the patients, 12 were male, 29 were female. The average age was 51 years old. The 41 patients had undergone gallbladder excision because of cholecystitis complicated lithiasis of gallbladder (32 cases), polypi of gallbladder or adenoma (9 cases). Postoperative pathology showed that 32 cases were adenocarcinoma of gallbladder, 6 cases were squamous carcinoma, 3 cases were squamous adenocarcinoma. Six cases were on the stage of Nevin I, 16 on Nevin II, 17 on Nevin III, 2 on Nevin IV. The second operation was performed after 6-30 d of the first operation. The second operation chose the improved method of Glenn excision of carcinoma of gallbladder.


RESULTS
On the second operation, 14 cases were with lymphatic metastasis, 14 with gallbladder metastasis, 6 with bile duct metastasis, 2 with pancreas metastasis. Fourteen cases were on the stage of Nevin IV, 9 on Nevin V, none on Nevin I, II and III. After the second operation, 1 year survival rate was 100% (41 cases); The three-year survival rate was 53.8% (22 cases); The five-year survival rate was 17.5% (7 cases).


CONCLUSIONS
Extended radical excision is one of the most important methods for the treatment of UGC.
Zhang
Ling
L
Department of Hepatobiliary and Pancreatic Surgery, Henan Tumor Hospital, Zhengzhou 450003, China.
Han
Feng
F
Huang
Chang-shan
CS
Pang
Chun
C
Han
You-zhi
YZ
Hua
Ya-wei
YW
D000328:Adult; D000368:Aged; D002763:Cholecystectomy / Q000379:methods*; D003951:Diagnostic Errors; D005260:Female; D005706:Gallbladder Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012086:Reoperation; D012189:Retrospective Studies; D015996:Survival Rate