Intravascular lymphomatosis presenting with sudden hearing loss.
Intravascular lymphoma (IVL) is a rare disorder characterized by the aggregation of malignant large cell lymphoma cells in small vessels. Neurological manifestations are typically the initial and, often the only, clinically obvious consequences of this malignancy. Diagnosis is dependent on biopsy or postmortem demonstration of the intravascular tumor. We report a patient in whom sudden hearing loss heralded IVL and propose that the hearing loss may have been the consequence of labyrinthine infarction consequent to the aggregation of malignant cells in the internal auditory artery.
Berger
Joseph R
JR
Department of Neurology, University of Kentucky College of Medicine, Lexington, KY 40536-0284, USA. jrbneuro@uky.edu
Jones
Raleigh
R
Wilson
Dianne
D
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001299:Audiometry; D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology; D002531:Cerebellum / Q000473:pathology; D003337:Corpus Callosum / Q000473:pathology; D017809:Fatal Outcome; D003639:Hearing Loss, Sudden / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D011239:Prednisolone