[Peculiarity of the antioxidant action of the extract from Aronia melanocarpa leaves antioxidant on the brain].
The antioxidant action of the extract from Aronia melanocarpa leaves on the brain was investigated. The intraperitoneal injection of extract in the dose of 0.2 g/kg prevented manifestations of oxidative stress in the brain induced by immobilization of rats. In vitro experiments revealed that the extract decreased intensity of ascorbate--and H2O2 -induced lipid and protein peroxidation in the brain homogenates. The most effect of the extract on ascorbate--induced lipid peroxidation was found in the postmitochondrial fraction of brain homogenate.
Cuvorova
I N
IN
Davydov
V V
VV
Prozorovskiĭ
V N
VN
Shvets
V N
VN
D000818:Animals; D001921:Brain / Q000503:physiopathology; D001923:Brain Chemistry / Q000187:drug effects*; D008297:Male; D010084:Oxidation-Reduction / Q000187:drug effects; D018384:Oxidative Stress / Q000187:drug effects*; D046936:Photinia / Q000737:chemistry; D010936:Plant Extracts / Q000008:administration & dosage*; D018515:Plant Leaves / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar
D010936:Plant Extracts