[Antibiotics in lower respiratory tract infection].
OBJECTIVE
Comparison of clinical outcome of lower respiratory tract infections in small children treated or not treated with antibiotics.


METHODS
Eighty seven children aged from 2 months to 5 years admitted to hospital with mild to moderate bronchitis and/or pneumonia were randomly allocated to one of two groups: group A children were treated with antibiotics and group B patients were not. The children remained under close clinical observation. The clinical outcome was considered good if symptoms of the disease decreased after 72 hours. In case of no clinical improvement or worsening, the children from group B received antibiotics and in children from group A antibiotic therapy was changed.


CONCLUSIONS
There were no significant differences between the two groups in the course of the disease, the frequency of pulmonary complications and recurrence during one month of follow-up.
Łuczak
Grazyna
G
Klinika Pediatrii, Gastroenterologii i Onkologii, Dziecieca Akademia Medyczna, 80-803 Gdańsk, Poland. gluczak@pf.pl
Kozielska
Ewa
E
Tyl
Joanna
J
Borkowska
Anna
A
Galińska
Anna
A
Plata-Nazar
Katarzyna
K
Kotłowska-Kmieć
Aldona
A
Bogotko-Szarszewska
Marta
M
Bohdan
Zbigniew
Z
D000284:Administration, Oral; D000658:Amoxicillin / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001991:Bronchitis / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000188:drug therapy; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control
D000900:Anti-Bacterial Agents; D000658:Amoxicillin