title: Microbiological analysis of chronic dacryocystitis.
abstract: OBJECTIVE
  To investigate the microbiology of specimens from patients with chronic dacryocystitis.
  
  
  METHODS
  A total of 100 samples were obtained from the contents of the lacrimal duct in 91 consecutive patients with chronic dacryocystitis, including nine bilateral cases. These samples were cultured for aerobic and anaerobic bacteria and fungi with a routine microbiological technique. Positive cultured isolates were identified.
  
  
  RESULTS
  A total of 180 strains were isolated from the 85 bacterial samples, including 150 strains of aerobic bacteria and 30 strains of anaerobic bacteria. Fungi were found in eight samples and actinomyces in three samples. The bacterial species that were most frequently found were Staphylococcus species, representing 34.5% of all strains, followed by Corynebacterium diphtheroides (15.5%). The sensitivity tests revealed that levo-ofloxacin and amikacin were the most effective antibiotics.
  
  
  CONCLUSIONS
  Gram positive cocci was the predominant pathogen of chronic dacryocystitis. Levo-ofloxacin and amikacin had the best effect in vitro.
authors.affiliation: Department of Eye Microbiology, Beijing Institute of Ophthalmology, China. sunxuguang@yahoo.com
authors.forename: Xuguang
authors.initials: X
authors.lastname: Sun
authors.forename: Qingfeng
authors.initials: Q
authors.lastname: Liang
authors.forename: Shiyun
authors.initials: S
authors.lastname: Luo
authors.forename: Zhiqun
authors.initials: Z
authors.lastname: Wang
authors.forename: Ran
authors.initials: R
authors.lastname: Li
authors.forename: Xiuying
authors.initials: X
authors.lastname: Jin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000583:Amikacin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001420:Bacteria, Aerobic / Q000302:isolation & purification; D001421:Bacteria, Anaerobic / Q000302:isolation & purification; D002908:Chronic Disease; D003353:Corynebacterium diphtheriae / Q000302:isolation & purification; D003607:Dacryocystitis / Q000188:drug therapy / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D007765:Lacrimal Apparatus / Q000382:microbiology*; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015242:Ofloxacin / Q000627:therapeutic use; D013210:Staphylococcus / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins; D000583:Amikacin; D015242:Ofloxacin