title: Near-miss SIDS due to Brugada syndrome.
abstract: A 19 day old infant was successfully resuscitated from ventricular fibrillation. The 12 lead ECG was normal, with a normal QT interval, and remains so over three years follow up. DNA analysis revealed a missense mutation (R1193Q) in the SCN5A gene, previously linked with familial sudden unexpected nocturnal death syndrome, also known as Brugada syndrome.
authors.affiliation: Department of Paediatric Cardiology, Starship Hospital, Grafton, Auckland, New Zealand. JSkinner@adhb.govt.nz
authors.forename: J R
authors.initials: JR
authors.lastname: Skinner
authors.forename: S-K
authors.initials: SK
authors.lastname: Chung
authors.forename: D
authors.initials: D
authors.lastname: Montgomery
authors.forename: C H
authors.initials: CH
authors.lastname: McCulley
authors.forename: J
authors.initials: J
authors.lastname: Crawford
authors.forename: J
authors.initials: J
authors.lastname: French
authors.forename: M I
authors.initials: MI
authors.lastname: Rees
mesh_terms: D004562:Electrocardiography; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D020125:Mutation, Missense / Q000235:genetics; D062554:NAV1.5 Voltage-Gated Sodium Channel; D015222:Sodium Channels / Q000235:genetics*; D013398:Sudden Infant Death / Q000235:genetics*; D014693:Ventricular Fibrillation / Q000235:genetics / Q000503:physiopathology / Q000628:therapy*
chemical_list: D062554:NAV1.5 Voltage-Gated Sodium Channel; C568320:SCN5A protein, human; D015222:Sodium Channels