title: Efficient batch and continuous flow Suzuki cross-coupling reactions under mild conditions, catalysed by polyurea-encapsulated palladium (II) acetate and tetra-n-butylammonium salts.
abstract: Suzuki cross-coupling reactions are effected in both conventional organic solvents, under continuous flow conditions at 70 degree C, and in batch mode in supercritical carbon dioxide (scCO2), at temperatures as low as 40 degrees C in the presence of palladium(II) acetate microencapsulated in polyurea [PdEnCat] and tetra-n-butylammonium salts.
authors.affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.
authors.forename: Connie K Y
authors.initials: CK
authors.lastname: Lee
authors.forename: Andrew B
authors.initials: AB
authors.lastname: Holmes
authors.forename: Steven V
authors.initials: SV
authors.lastname: Ley
authors.forename: Ian F
authors.initials: IF
authors.lastname: McConvey
authors.forename: Bushra
authors.initials: B
authors.lastname: Al-Duri
authors.forename: Gary A
authors.initials: GA
authors.lastname: Leeke
authors.forename: Regina C D
authors.initials: RC
authors.lastname: Santos
authors.forename: Jonathan P K
authors.initials: JP
authors.lastname: Seville
mesh_terms: D000085:Acetates / Q000737:chemistry*; D001713:Biphenyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002245:Carbon Dioxide / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D012492:Salts / Q000737:chemistry; D013696:Temperature
chemical_list: D000085:Acetates; D001713:Biphenyl Compounds; D009942:Organometallic Compounds; D011108:Polymers; D000644:Quaternary Ammonium Compounds; D012492:Salts; C516071:palladium(II) acetate; D002245:Carbon Dioxide; C045786:polyurea; C009405:tetrabutylammonium