Cyclobutane dimers from the Colombian medicinal plant Achyrocline bogotensis.
Five cyclobutane dimers, achyrodimers A-E (1-5), along with 11 known compounds were isolated from the methanol extract of the Colombian medicinal plant Achyrocline bogotensis. Their structures were elucidated by spectroscopy. Several of these compounds were screened for cytokine-inducing activity in human peripheral blood mononuclear cells.
Sagawa
Takaaki
T
Graduate School of Pharmaceutical Sciences, University of Tokushima, Sho-machi, Tokushima 770-8505, Japan.
Takaishi
Yoshihisa
Y
Fujimoto
Yoshinori
Y
Duque
Carmenza
C
Osorio
Coralia
C
Ramos
Freddy
F
Garzon
Cristina
C
Sato
Mitsunobu
M
Okamoto
Masato
M
Oshikawa
Tetsuya
T
Ahmed
Sharif Uddin
SU
D036921:Achyrocline / Q000737:chemistry*; D003105:Colombia; D003503:Cyclobutanes / Q000097:blood / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016207:Cytokines / Q000096:biosynthesis; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*
D003503:Cyclobutanes; D016207:Cytokines