Clinical neurophysiology of dystonia.
It took decades to accept that dystonia, a bizarre condition which often produces abnormal movements exclusively during specific activities like writing, was due to brain disease. Clinical neurophysiology certainly added to this evolution of thinking. Recent neurophysiological observations demonstrate that dystonia is not only due to an isolated brain motor dysfunction, but also to sensory and sensorimotor integration disturbances. We hope that new treatment strategies will arise thanks to our better understanding of dystonia pathophysiology.
Mavroudakis
Nicolas
N
Laboratoire de Neurophysiologie clinique, Service de Neurologie, Hôpital Erasme, Brussels, Belgium. nmavroud@ulb.ac.be
D002540:Cerebral Cortex / Q000503:physiopathology*; D004421:Dystonia / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D009482:Neurophysiology