title: [Bone integration and apposition of porous and non porous metallic orthopaedic biomaterials].
abstract: The objective of this study was to evaluate the functionality of two intervertebral fusion implants, a porous nickel-titanium and a conventional titanium cage system in a sheep model. Eighteen sheep each received the two-implant devices at L2-L3 and L4-L5 lumbar levels. The sheep were sacrificed at three different postsurgical periods: three, six and 12 months. Lumbar segments were harvested. Qualitative (macroscopic and microscopic) and quantitative (histomorphometric) histological analysis were carried out on histological slides. The results indicated that a porous nickel-titanium had obtained a better osseointegration than the titanium implant. The functionality of two implants seemed to be influenced by the implant structure and shape. However, biocompatibility of two implants seemed comparable.
authors.affiliation: Centre de recherche, hôpital Sainte-Justine, 3175 chemin Côte-Ste-Cathérine, H3T 1C5 Montréal (QC), Canada.
authors.forename: F
authors.initials: F
authors.lastname: Likibi
authors.forename: M
authors.initials: M
authors.lastname: Assad
authors.forename: C
authors.initials: C
authors.lastname: Coillard
authors.forename: G
authors.initials: G
authors.lastname: Chabot
authors.forename: C-H
authors.initials: CH
authors.lastname: Rivard
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D004195:Disease Models, Animal; D008159:Lumbar Vertebrae / Q000601:surgery*; D008422:Materials Testing; D009532:Nickel; D016062:Porosity; D012756:Sheep; D013123:Spinal Fusion / Q000295:instrumentation* / Q000379:methods*; D014025:Titanium
chemical_list: D001672:Biocompatible Materials; D009532:Nickel; D014025:Titanium