Zolpidem at supratherapeutic doses can cause drug abuse, dependence and withdrawal seizure.
Zolpidem is a non-benzodiazepine hypnotic drug, acts selectively through omega 1 receptors of GABAA. It is thought to be safer than benzodiazepines but we report a case of zolpidem drug abuse, dependence and withdrawal seizure.
Sethi
P K
PK
Department of Neurology, Sir Ganga Ram Hospital, New Delhi-110060.
Khandelwal
D C
DC
D000328:Adult; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D016584:Panic Disorder / Q000188:drug therapy; D011725:Pyridines / Q000008:administration & dosage / Q000009:adverse effects*; D012307:Risk Factors; D012640:Seizures / Q000139:chemically induced*; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy; D013375:Substance Withdrawal Syndrome / Q000209:etiology*; D019966:Substance-Related Disorders / Q000209:etiology* / Q000517:prevention & control; D000077334:Zolpidem
D006993:Hypnotics and Sedatives; D011725:Pyridines; D000077334:Zolpidem