title: The histopathological and immunohistochemical diagnosis in small cell lung carcinoma.
abstract: The small cells lung carcinoma (SCLC) represents 10-25% of the bronchogenical carcinomas, prevails at middle ages and is closely associated with tobacco smoke. It belongs to the group of carcinomas with neuroendocrine differentiation, the patients presenting various paraneoplastic syndromes. The study was performed on 491 patients with a clinical and radiological suspicion of bronchopulmonary cancer. In this study, the histopathological examination gives results similar to those mentioned in the medical literature for the small cells lung carcinoma, prevailing in the case of young patients. The immunohistochemical examinations are particularly precious in confirming the diagnosis, especially in the diagnosis of the lymphonodular micrometastases.
authors.affiliation: Faculty of Medicine and Pharmacy, University of Oradea.
authors.forename: A M
authors.initials: AM
authors.lastname: Dragan
authors.forename: G
authors.initials: G
authors.lastname: Simu
authors.forename: T
authors.initials: T
authors.lastname: Vaida
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001999:Bronchoscopy; D018288:Carcinoma, Small Cell / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology; D002864:Chromogranins / Q000378:metabolism; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D012907:Smoking
chemical_list: D002864:Chromogranins