Intricarene, an unprecedented trispiropentacyclic diterpene from the Caribbean Sea plume Pseudopterogorgia kallos.
[structure: see text] A novel trispiropentacyclic diterpene, intricarene (1), was isolated from the hexane extract of the Caribbean gorgonian octocoral Pseudopterogorgia kallos. Its highly entangled structure was established by interpretation of NMR, IR, UV, and HREIMS data and subsequently confirmed by X-ray diffraction analysis. The unprecedented carbon skeleton of 1 constitutes a new addition to the already impressive architectural diversity of the diterpene class of marine secondary metabolites.
Marrero
Jeffrey
J
Department of Chemistry, University of Puerto Rico, P.O. Box 23346, U.P.R. Station, San Juan, Puerto Rico 00931-3346.
Rodríguez
Abimael D
AD
Barnes
Charles L
CL
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification; D006572:Heterocyclic Compounds, Bridged-Ring / Q000737:chemistry / Q000302:isolation & purification; D008968:Molecular Conformation; D014315:Triterpenes
D004224:Diterpenes; D006572:Heterocyclic Compounds, Bridged-Ring; D014315:Triterpenes; C507581:intricarene