title: [Is antenatal corticosteroid administration associated with increased acid gastroesophageal reflux in preterm neonates?].
abstract: OBJECTIVE
  Preliminary assessment of the incidence of acid gastroesophageal reflux in preterm neonates with and without antenatal administration of steroids.
  
  
  METHODS
  Analysis of 96 neonates born before 34 weeks of pregnancy was undertaken. The patients were divided into two groups: I - those who received antenatal corticosteroids n=22; II - those who received no antenatal corticosteroids n=74. All patients had 24-hour pH-metry and basing on the result of this examination we diagnosed or excluded acid gastroesophageal reflux.
  
  
  RESULTS
  In group I gastroesophageal reflux was diagnosed in 9/22 neonates (40.9%), in group II in 12/72 (16.2%), odds ratio=3.58.
  
  
  CONCLUSIONS
  The frequency of acid gastroesophageal reflux is higher in preterm infants who received antenatal corticosteroids.
authors.affiliation: Oddział Noworodków, Wcześniaków i Intensywnej Terapii Noworodka, SPZOZ Wojewódzkiego Szpitala im. J. Biziela, Ujejeskiego 75, Bygdoszcz, Poland. iesadowska@poczta.onet.pl
authors.forename: Iwona
authors.initials: I
authors.lastname: Sadowska-Krawczenko
authors.forename: Mieczyslawa
authors.initials: M
authors.lastname: Czerwionka-Szaflarska
authors.forename: Piotr
authors.initials: P
authors.lastname: Korbal
mesh_terms: D001623:Betamethasone / Q000009:adverse effects; D003907:Dexamethasone / Q000009:adverse effects; D005260:Female; D005764:Gastroesophageal Reflux / Q000139:chemically induced*; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000139:chemically induced*; D008297:Male; D008431:Maternal-Fetal Exchange; D007752:Obstetric Labor, Premature / Q000188:drug therapy; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000139:chemically induced*
chemical_list: D005938:Glucocorticoids; D003907:Dexamethasone; D001623:Betamethasone