Increasing the degrees of freedom in existing group randomized trials: the df* approach.
This study describes a method for incorporating external estimates of intraclass correlation to improve the precision for the analysis of an existing group-randomized trial. The authors use a random-effects meta-analytic approach to pool the information across studies, which takes into account any interstudy heterogeneity that may exist. This approach can be used in several different situations to estimate the degrees of freedom available for an adjusted test of the intervention effect in a study where the challenges of group-randomized trials were not fully considered when the study was planned. The authors discuss the limitations of this approach and the circumstances in which it is likely to be helpful.
Blitstein
Jonathan L
JL
Psychology of Health Behavior Program, RTI International.
Hannan
Peter J
PJ
Murray
David M
DM
Shadish
William R
WR
D006801:Humans; D015201:Meta-Analysis as Topic; D015233:Models, Statistical; D016032:Randomized Controlled Trials as Topic; D012107:Research Design / Q000706:statistics & numerical data*