title: [Prediction of serotypes of dengue virus by response to IgM antibodies].
abstract: A study of 4 groups of serum samples from Cuba, Costa Rica, Nicaragua and Panama was made to determine the serotypes of dengue virus causing epidemics or outbreaks by using IgM antibody-capture ELISA(MAC-ELISA). Dengue-IgM diagnostic kit was independently used in each of the serotypes and an index value was calculated (optical density of the sample/cut-off value) in each case, with which two statistical analyses were made: Fisher's variances and Litter significant difference (LSD) calculation. Such calculations allowed determining that in Cuba and Panama, serotype 2 circulated whereas in Costa Rica, serotype 1 prevailed. These were the isolated serotypes in various epidemics. Regarding Nicaragua, very heterogeneous responses were obtained, the responsible serotype could not be determined since more than two serotypes co-circulated in this country.
authors.affiliation: Instituto de Medicina Tropical "Pedro Kouri", Ciudad de La Habana, Cuba.
authors.forename: Iselys
authors.initials: I
authors.lastname: Delgado
authors.forename: Susana
authors.initials: S
authors.lastname: Vásquez
authors.forename: José Ramón
authors.initials: JR
authors.lastname: Bravo
authors.forename: Maria Guadalupe
authors.initials: MG
authors.lastname: Guzmán
mesh_terms: D003716:Dengue Virus / Q000145:classification* / Q000276:immunology*; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology*; D011237:Predictive Value of Tests; D012703:Serotyping
chemical_list: D007075:Immunoglobulin M