Pulmonary tailoring and lobar transplantation to overcome size disparities in lung transplantation.
Size matching between donors and recipients represents one of the organ distribution criteria widely accepted by lung transplant teams. However, in some cases it is not possible to allocate a donor to the corresponding size-compatible recipient. To avoid possible complications derived from the implantation of oversized lungs into smaller recipients, surgical procedures such as pulmonary tailoring and lobar transplantation have been advocated. We review our experience in 13 patients undergoing volume reduction of the lung graft at the time of transplantation, either by nonanatomical lung volume reduction or by lobar transplantation. There were no significant differences between lung-downsized patients and standard lung transplantation patients in terms of donor characteristics, surgical and postoperative complications, functional outcome, and survival. We conclude that downsizing the lung graft either by nonanatomical resection or lobar transplantation is safe and reliable to overcome size disparities between donor and recipients, with no additional morbidity and with similar early and midterm outcomes to those in standard lung transplants.
Santos
F
F
Department of Respiratory Medicine, Lung Transplantation Unit, University Hospital Reina Sofia, Córdoba, Spain. fsantos_@supercable.es
Lama
R
R
Alvarez
A
A
Algar
F J
FJ
Quero
F
F
Cerezo
F
F
Salvatierra
A
A
Baamonde
C
C
D000017:ABO Blood-Group System; D000293:Adolescent; D000328:Adult; D049628:Body Size; D005260:Female; D005500:Follow-Up Studies; D006650:Histocompatibility Testing; D006801:Humans; D008168:Lung / Q000033:anatomy & histology*; D016040:Lung Transplantation / Q000379:methods* / Q000401:mortality / Q000502:physiology; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy / Q000379:methods*; D012086:Reoperation; D012129:Respiratory Function Tests; D012189:Retrospective Studies; D016019:Survival Analysis; D020858:Tissue and Organ Harvesting / Q000379:methods*
D000017:ABO Blood-Group System