Chronic pancreatitis with pancreaticolithiasis and pseudocyst in a 5-year-old boy with homozygous SPINK1 mutation.
We report a 5-year-old boy with a 5-month history of symptoms owing to chronic pancreatitis. Abdominal imaging revealed a large pseudocyst in the pancreatic tail and concretions in the main pancreatic duct. Successful endoscopic papillotomy and stent implantation were performed. Genetic testing showed homozygous SPINK1-N34S mutation, which is an established risk factor for chronic pancreatitis.
Kühn
Axel C
AC
Department of Diagnostic Radiology -- Pediatric Radiology, Faculty of Medicine, University of Leipzig, Oststr. 21-25, 04317 Leipzig, Germany.
Teich
Niels
N
Caca
Karel
K
Limbach
Anne
A
Hirsch
Wolfgang
W
D002675:Child, Preschool; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002908:Chronic Disease; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D006801:Humans; D020347:Lithiasis / Q000175:diagnosis* / Q000235:genetics* / Q000628:therapy; D008297:Male; D009154:Mutation; D010182:Pancreatic Diseases / Q000175:diagnosis* / Q000235:genetics* / Q000628:therapy; D010192:Pancreatic Pseudocyst / Q000175:diagnosis* / Q000235:genetics* / Q000628:therapy; D010195:Pancreatitis / Q000175:diagnosis* / Q000235:genetics* / Q000628:therapy; D015607:Stents; D014359:Trypsin Inhibitor, Kazal Pancreatic / Q000235:genetics*
D014359:Trypsin Inhibitor, Kazal Pancreatic