Spatial sensitivity in the dorsal zone (area DZ) of cat auditory cortex.
We compared the spatial sensitivity of neural responses in three areas of cat auditory cortex: primary auditory cortex (A1), the posterior auditory field (PAF), and the dorsal zone (DZ). Stimuli were 80-ms pure tones or broadband noise bursts varying in free-field azimuth (in the horizontal plane) or elevation (in the vertical median plane), presented at levels 20-40 dB above units' thresholds. We recorded extracellular spike activity simultaneously from 16 to 32 sites in one or two areas of alpha-chloralose-anesthetized cats. We examined the dependence of spike counts and response latencies on stimulus location as well as the information transmission by neural spike patterns. Compared with units in A1, DZ units exhibited more complex frequency tuning, longer-latency responses, increased prevalence and degree of nonmonotonic rate-level functions, and weaker responses to noise than to tonal stimulation. DZ responses also showed sharper tuning for stimulus azimuth, stronger azimuthal modulation of first-spike latency, and enhanced spatial information transmission by spike patterns, compared with A1. Each of these findings was similar to differences observed between PAF and A1. Compared with PAF, DZ responses were of shorter overall latency, and more DZ units preferred stimulation from ipsilateral azimuths, but the majority of analyses suggest strong similarity between PAF and DZ responses. These results suggest that DZ and A1 are physiologically distinct cortical fields and that fields like PAF and DZ might constitute a "belt" region of auditory cortex exhibiting enhanced spatial sensitivity and temporal coding of stimulus features.
Stecker
G Christopher
GC
Kresge Hearing Research Institute, University of Michigan, Ann Arbor, MI, USA. jmidd@umich.edu
Harrington
Ian A
IA
Macpherson
Ewan A
EA
Middlebrooks
John C
JC
D000161:Acoustic Stimulation / Q000379:methods; D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001303:Auditory Cortex / Q000033:anatomy & histology / Q000502:physiology*; D001306:Auditory Pathways / Q000502:physiology; D001309:Auditory Threshold / Q000502:physiology; D001931:Brain Mapping; D002415:Cats; D003198:Computer Simulation; D004307:Dose-Response Relationship, Radiation; D005260:Female; D008297:Male; D011930:Reaction Time / Q000502:physiology; D013017:Sound Localization / Q000502:physiology*; D013028:Space Perception / Q000502:physiology*