title: Reversible dilated cardiomyopathy associated with amphotericin B treatment.
abstract: We report two patients, who developed dilated cardiomyopathy and subsequent congestive heart failure after treatment with amphotericin B (AmB). The echocardiographic findings and the symptoms of heart failure resolved after the discontinuation of the drug. The clinical data from our cases and two similar cases reported in the literature suggest that the presence of other factors predisposing to cardiac dysfunction may facilitate the occurrence of this rare side effect.
authors.affiliation: Department of Cardiology, Laikon General Hospital, Athens, Greece.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Moyssakis
authors.forename: Theodoros P
authors.initials: TP
authors.lastname: Vassilakopoulos
authors.forename: Nikolaos V
authors.initials: NV
authors.lastname: Sipsas
authors.forename: Alexandros
authors.initials: A
authors.lastname: Perakis
authors.forename: Alexandra
authors.initials: A
authors.lastname: Petrou
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Kosmas
authors.forename: Gerassimos A
authors.initials: GA
authors.lastname: Pangalis
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage / Q000009:adverse effects*; D000935:Antifungal Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002177:Candidiasis / Q000188:drug therapy; D009202:Cardiomyopathies / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D052776:Female Urogenital Diseases / Q000188:drug therapy / Q000382:microbiology; D005334:Fever / Q000188:drug therapy; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D052801:Male Urogenital Diseases; D008875:Middle Aged; D028761:Withholding Treatment
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B