title: Routine enteral nutrition in neonates on extracorporeal membrane oxygenation.
abstract: OBJECTIVE
  To evaluate over a 5-yr period the feasibility and tolerance of a protocol of routine enteral nutrition in neonates requiring extracorporeal membrane oxygenation (ECMO).
  
  
  METHODS
  Retrospective medical chart review.
  
  
  METHODS
  Level III children's hospital, pediatric surgical intensive care unit.
  
  
  METHODS
  Neonates treated with venoarterial ECMO (VA-ECMO) between January 1997 and January 2002. Patients with congenital diaphragmatic hernia were excluded.
  
  
  METHODS
  None.
  
  
  RESULTS
  Charts of all neonates treated with VA-ECMO were reviewed. Feasibility was evaluated by recording the time period needed for enteral nutrition to reach 40% of total fluid intake; tolerance was evaluated by reviewing data on enteral nutrition related morbidity. Sixty-seven of the 77 eligible patients received enteral feeding during ECMO. Thirty-six of these patients (54%) received 40% of total fluid intake as enteral nutrition within a median of 3 (range, 2-4) days. Over the years there was a trend toward an increasing usage of enteral nutrition from 71% to 94% (p = .07). Enteral nutrition was temporarily discontinued in 16 patients, with 14 showing gastric retentions, one showing discomfort, and one showing aspiration. Symptoms of bilious vomiting, blood-stained stool, or abdominal distention were not present.
  
  
  CONCLUSIONS
  Neonates on ECMO in this series tolerated enteral feeding well and did not show serious adverse effects. Overall, it is our experience that routine use of enteral feeding in critically ill neonates on VA-ECMO is feasible.
authors.affiliation: Department of Pediatric Surgery, Pediatric Surgical Intensive Care Unit, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands.
authors.forename: Manon N
authors.initials: MN
authors.lastname: Hanekamp
authors.forename: Marjolein
authors.initials: M
authors.lastname: Spoel
authors.forename: Irene
authors.initials: I
authors.lastname: Sharman-Koendjbiharie
authors.forename: Jeroen W B
authors.initials: JW
authors.lastname: Peters
authors.forename: Marcel J I J
authors.initials: MJ
authors.lastname: Albers
authors.forename: Dick
authors.initials: D
authors.lastname: Tibboel
mesh_terms: D004750:Enteral Nutrition / Q000009:adverse effects; D015199:Extracorporeal Membrane Oxygenation; D005240:Feasibility Studies; D006801:Humans; D007231:Infant, Newborn; D012189:Retrospective Studies; D016896:Treatment Outcome