Development and characterization of a new stationary phase for an immunoadsorption wall.
This study introduces a newly developed method for the formation of a stationary phase superficially embedded with immunoadsorbent, that is partially incomplete two-stage polymerization of acrylamide. Preliminary experimental studies show that binding activity of the immunoadsorbent was satisfactorily maintained after immobilization. With an appropriate configuration of selected immunoadsorption matrices and immunoisolation barriers, it is hoped that this stationary phase could be used to resolve some difficult problems arising from the accumulation of certain middle molecular weight toxins not removed by other blood purification procedures.
Yang
Tsung-Hua
TH
Department of Chemical Engineering, Cheng Shiu University, Kaohsiung, Taiwan, Republic of China. thyang@csu.edu.tw
D020106:Acrylamide / Q000737:chemistry*; D001672:Biocompatible Materials; D007163:Immunosorbent Techniques / Q000295:instrumentation; D007164:Immunosorbents / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry
D001672:Biocompatible Materials; D007164:Immunosorbents; D011108:Polymers; D020106:Acrylamide