Non-homogeneous hyperechogenic echo pattern three days after frozen embryo transfer is associated with lower pregnancy rates.
OBJECTIVE
To evaluate the association of mid-luteal phase echo patterns and pregnancy rates (PRs) following frozen embryo transfer (ET).


METHODS
Sonographic evaluation of endometrial echo patterns was performed three days after ET in the first frozen ET cycle of women < 40 years of age who used their own oocytes as well as all donor oocyte recipients.


RESULTS
The distribution of echo patterns and clinical PRs were similar in women using their own eggs and women who used donor oocytes; therefore all data was combined. The clinical PR was 49.5% with a hyperechogenic echo pattern vs 38.8% with a non-hyperechogenic pattern, p = .007.


CONCLUSIONS
A larger study of frozen ET and mid-luteal echo pattern now demonstrates conclusions similar to the data from fresh ET in hyperstimulated in vitro fertilization (IVF)-ET cycles in that failure to attain a hyperechogenic echo pattern three days after ET is associated with lower pregnancy rates.
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J H
JH
The University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, USA.
Dietterich
C
C
Nazari
A
A
Lurie
D
D
Choe
J K
JK
Check
M L
ML
D000328:Adult; D015925:Cryopreservation; D004624:Embryo Transfer; D004717:Endometrium / Q000000981:diagnostic imaging*; D004967:Estrogens / Q000627:therapeutic use; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use; D006801:Humans; D016729:Leuprolide / Q000627:therapeutic use; D008183:Luteal Phase / Q000502:physiology*; D011247:Pregnancy; D018873:Pregnancy Rate; D011374:Progesterone / Q000627:therapeutic use; D011446:Prospective Studies; D014019:Tissue Donors; D018615:Ultrasonography, Doppler, Color
D004967:Estrogens; D005300:Fertility Agents, Female; D011374:Progesterone; D016729:Leuprolide