title: Time-course characteristics for the digestion of endogenous as well as exogenous protein in the small intestine: a case study with rats fed a [15N]-soy protein isolate.
abstract: A study was conducted to evaluate a net value of exogenous (dietary) protein nutrition in rats fed a [15N]-labeled soy protein isolate (SPI). Although [15N]-SPI-derived nitrogen reached a plateau 2 hr after feeding, it accounted for only a half of the total nitrogen in the small intestine. 15N was confirmed that was normally transported to liver, kidney, spleen, and brain. The present study reveals the large degree of participation of endogenous proteins in dietary SPI during small-intestinal digestion.
authors.affiliation: Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8687, Japan.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Nakai
authors.forename: Shinji
authors.initials: S
authors.lastname: Okada
authors.forename: Ichiro
authors.initials: I
authors.lastname: Matsumoto
authors.forename: Tomiko
authors.initials: T
authors.lastname: Asakura
authors.forename: Hiroko
authors.initials: H
authors.lastname: Kimura
mesh_terms: D000821:Animal Feed; D000818:Animals; D004044:Dietary Proteins / Q000008:administration & dosage / Q000378:metabolism / Q000493:pharmacokinetics / Q000494:pharmacology; D004063:Digestion / Q000502:physiology*; D007421:Intestine, Small / Q000378:metabolism*; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D009587:Nitrogen Isotopes; D009747:Nutritional Physiological Phenomena / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D030262:Soybean Proteins / Q000008:administration & dosage / Q000378:metabolism* / Q000493:pharmacokinetics / Q000494:pharmacology*; D013997:Time Factors; D014018:Tissue Distribution
chemical_list: D004044:Dietary Proteins; D009587:Nitrogen Isotopes; D030262:Soybean Proteins; D009584:Nitrogen