title: Long-term outcome of right split in situ grafts in adults.
abstract: In situ split liver transplants represent a technical progression from ex situ split procedures conceived to retrieve grafts for pediatric recipients. The transection line runs along the falciform ligament, so the main artery to the right graft is the right proper artery, whereas the left graft retains the main arterial axis with the celiac trunk. Although the major advantages are for pediatric recipients, due to the expanded pool of grafts available, for adult recipients the results of right split in situ grafts must be compared with whole grafts. We considered two groups of consecutive grafts transplanted since 1993 as first grafts: 20 of the former and 261 of the latter. Groups were comparable for donor gender, recipient age and gender, perfusion solution, ischemia time, and follow-up time, but not for donor age and for the number of arterial anastomoses. Although there were more major surgical complications in the former compared with the latter group (40% vs 25%), the only statistically significant difference was found in retransplantation rate for arterial complications (15% vs 2.2%). No statistical difference was observed in graft or patient actuarial survival rates at 1, 3, or 6 years after transplantation; for right split grafts these were 85%, 69%, and 69% and 95%, 79%, and 79%, respectively.
authors.affiliation: Centro Trapianti Fegato, Ospedale Maggiore Policlinico IRCCS di Milano, Milano, Italy. u.maggi@tiscali.it
authors.forename: U
authors.initials: U
authors.lastname: Maggi
authors.forename: L
authors.initials: L
authors.lastname: Caccamo
authors.forename: E
authors.initials: E
authors.lastname: Melada
authors.forename: S
authors.initials: S
authors.lastname: Gatti
authors.forename: G
authors.initials: G
authors.lastname: Rossi
authors.forename: P
authors.initials: P
authors.lastname: Reggiani
authors.forename: G
authors.initials: G
authors.lastname: Paone
authors.forename: A
authors.initials: A
authors.lastname: Giussani
authors.forename: P
authors.initials: P
authors.lastname: Bertoli
authors.forename: L R
authors.initials: LR
authors.lastname: Fassati
mesh_terms: D000328:Adult; D000714:Anastomosis, Surgical; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006498:Hepatectomy / Q000379:methods*; D006499:Hepatic Artery / Q000601:surgery; D006801:Humans; D007083:Iliac Artery / Q000601:surgery; D008107:Liver Diseases / Q000145:classification / Q000601:surgery; D016031:Liver Transplantation / Q000379:methods* / Q000401:mortality / Q000502:physiology; D008297:Male; D017538:Mesenteric Artery, Superior / Q000601:surgery; D008875:Middle Aged; D012086:Reoperation / Q000706:statistics & numerical data; D012189:Retrospective Studies; D016019:Survival Analysis; D013997:Time Factors; D020858:Tissue and Organ Harvesting / Q000379:methods*