title: [Assessment of left ventricular systolic and diastolic function by Doppler tissue imaging in patients with chronic heart failure].
abstract: OBJECTIVE
  To investigate the application of pulsed-wave Doppler tissue imaging ( PW-DTI) in evaluating left ventricular systolic and diastolic function in patients with chronic heart failure (CHF).
  
  
  METHODS
  Mitral annular velocities (MAV) were measured by PW-DTI in 35 patients with CHF and 25 healthy subjects. Traditional indices for evaluating the global left ventricular function by conventional echocardiography were also studied as a comparison.
  
  
  RESULTS
  Peak systolic, peak early diastolic, peak late diastolic mitral annular velocities ( Sa, Ea, Aa), and Ea/Aa ratio progressively decreased in CHF patients compared with the healthy subjects (P <0.01 ). Sa of the mitral annulus correlated linearly with the left ventricle ejection fraction (LVEF) (r =0.890, P < 0.01). Compared with the healthy subjects, Ea in all 3 subgroups of diastolic dysfunction in the CHF group significantly decreased (P <0.01). Aa in 2 subgroups (pseudonormal filling and restrictive filling) decreased (P < 0.01 ) and the decreased Ea/Aa was found in the delayed relaxation and pseudonormal filling subgroups compared with the healthy subjects (P<0.001).
  
  
  CONCLUSIONS
  MAV measured by PW-DTI can be used for assessing the left ventricular systolic and diastolic function in CHF patients.
authors.affiliation: Department of Cardiology, Xiangya Hospital, Changsha 410008, China. Zhangsaidanli@126.com
authors.forename: Sai-dan
authors.initials: SD
authors.lastname: Zhang
authors.forename: Sheng-ling
authors.initials: SL
authors.lastname: Zhang
authors.forename: Hong-yan
authors.initials: HY
authors.lastname: Zhou
authors.forename: Hui-ying
authors.initials: HY
authors.lastname: Li
authors.forename: Qing-jun
authors.initials: QJ
authors.lastname: Gui
mesh_terms: D003971:Diastole; D018619:Echocardiography, Doppler, Pulsed; D005260:Female; D006333:Heart Failure / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D013599:Systole; D016277:Ventricular Function, Left / Q000502:physiology*