title: Characteristics of live bovine herpesvirus-1 vaccines.
abstract: The common disease caused by bovine herpes virus 1 infection is febrile rhinotracheitis (FRT) and under certain conditions the virus is strongly implicated in pre-disposing cattle to pneumonic pasteurellosis. These illnesses account for a significant economic loss in the cattle industry worldwide and vaccination is widely applied. In naive cattle, and for a short period of time, old and new vaccines significantly reduce clinical signs of FRT and also virus shedding. A single intranasal vaccination affords significant protection in face of maternally derived antibodies, and the protection can be significantly prolonged by a booster intramuscular vaccination. Current data recommend vaccination in face of an outbreak and vaccines appear safe for pregnant cattle.
authors.affiliation: Intervet UK Ltd., Huntingdon, Cambridgeshire PE28 2BQ, UK. jay.patel@intervet.com
authors.forename: J R
authors.initials: JR
authors.lastname: Patel
mesh_terms: D000818:Animals; D002417:Cattle; D005260:Female; D007242:Herpesvirus 1, Bovine / Q000276:immunology*; D007241:Infectious Bovine Rhinotracheitis / Q000517:prevention & control* / Q000821:virology; D007273:Injections, Intramuscular / Q000662:veterinary; D008297:Male; D009297:Nasal Mucosa / Q000821:virology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control* / Q000821:virology; D016896:Treatment Outcome; D014611:Vaccination / Q000662:veterinary*; D014765:Viral Vaccines / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D017201:Virus Shedding
chemical_list: D014765:Viral Vaccines