[Thyroid carcinoma].
Among thyroid carcinomas, thyroglobulin is a good tumor marker for differentiated carcinoma (papillary carcinoma, follicular carcinoma). In particular, it is widely used for monitoring of patients with total or near-total thyroidectomy. On the other hand, medullary thyroid caricima has a very sensitive and specific tumor marker, calcitonin. In inherited medullary carcinoma (multiple endocrine neoplasia type 2), RET protooncogene analysis is the best for detecting early medullary thyroid carcinoma.
Tamaki
Hiroshi
H
Dept of Surgery, Teikyo University School of Medicine.
D018263:Adenocarcinoma, Follicular / Q000175:diagnosis; D014408:Biomarkers, Tumor / Q000097:blood*; D002116:Calcitonin / Q000097:blood*; D002272:Carcinoembryonic Antigen / Q000097:blood; D018276:Carcinoma, Medullary / Q000175:diagnosis; D002291:Carcinoma, Papillary / Q000175:diagnosis; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D015592:Immunoradiometric Assay; D018814:Multiple Endocrine Neoplasia Type 2b / Q000175:diagnosis / Q000235:genetics; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D051096:Proto-Oncogene Proteins c-ret; D020794:Receptor Protein-Tyrosine Kinases / Q000235:genetics*; D013954:Thyroglobulin / Q000097:blood*; D013964:Thyroid Neoplasms / Q000175:diagnosis*; D013965:Thyroidectomy
D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D011518:Proto-Oncogene Proteins; D002116:Calcitonin; D013954:Thyroglobulin; D051096:Proto-Oncogene Proteins c-ret; D020794:Receptor Protein-Tyrosine Kinases