title: Delayed contrast-enhanced MRI of the aortic wall in Takayasu's arteritis: initial experience.
abstract: OBJECTIVE
  Delayed contrast-enhanced MRI is increasingly being used for cardiac viability imaging. Takayasu's arteritis is a rare inflammatory disorder of unknown cause that affects the aorta, its major branches, and the pulmonary artery; it is characterized by inflammation and fibrosis in the arterial wall. We report our initial experience with seven patients (six women, one man; age range, 25-62 years) with delayed (20 min) gadolinium-enhanced MRI (inversion recovery prepared gated fast gradient-echo pulse sequence) in patients with known Takayasu's arteritis.
  
  
  CONCLUSIONS
  Patients with Takayasu's arteritis (particularly those with abnormal laboratory values) have evidence of delayed hyper-enhancement on delayed contrast-enhanced MRI. Thus, delayed contrast-enhanced MRI might be a useful technique to identify inflammation in arterial wall.
authors.affiliation: Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA.
authors.forename: Milind Y
authors.initials: MY
authors.lastname: Desai
authors.forename: John H
authors.initials: JH
authors.lastname: Stone
authors.forename: Thomas K F
authors.initials: TK
authors.lastname: Foo
authors.forename: David B
authors.initials: DB
authors.lastname: Hellmann
authors.forename: João A C
authors.initials: JA
authors.lastname: Lima
authors.forename: David A
authors.initials: DA
authors.lastname: Bluemke
mesh_terms: D000328:Adult; D001018:Aortic Diseases / Q000473:pathology*; D003287:Contrast Media; D018450:Disease Progression; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D013625:Takayasu Arteritis / Q000473:pathology*
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA