[Gonadotropins and ovarian cancer].
The ovary is a tissue, which is sensitive to gonadotropins. Gonadotropins receptors are present in the epithelium and stroma of the ovary. Data from epidemiological study clearly shows, that development of tumor is correlated with morphological and biochemical processes taking place in the gonad. The role of gonadotropins, as well as the role of their receptors in the proliferation of the ovarian tissue was shown. Further research is needed to explain the molecular mechanism of gonadotropin activity in ovarian tissue, however the important role of gonadotropins in the pathology of ovarian tissue is already well established.
Nowak-Markwitz
Ewa
E
Klinika Onkologii Ginekologicznej, AM im Karola Marcinkowskiego w Poznaniu.
Jankowska
Anna
A
Spaczyński
Marek
M
D049109:Cell Proliferation; D006063:Chorionic Gonadotropin / Q000378:metabolism*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism; D006062:Gonadotropins / Q000378:metabolism; D006801:Humans; D007986:Luteinizing Hormone / Q000378:metabolism; D010051:Ovarian Neoplasms / Q000378:metabolism*; D011962:Receptors, FSH / Q000378:metabolism; D011967:Receptors, Gonadotropin / Q000378:metabolism; D011974:Receptors, LH / Q000378:metabolism
D006063:Chorionic Gonadotropin; D006062:Gonadotropins; D011962:Receptors, FSH; D011967:Receptors, Gonadotropin; D011974:Receptors, LH; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone