title: Buried chip skin grafting in neuropathic diabetic foot ulcers following vacuum-assisted wound bed preparation: enhancing a classic surgical tool with novel technologies.
abstract: In patients with diabetes mellitus, complications such as polyneuropathy and peripheral angiopathy inevitably lead to diabetic foot complications including foot ulcers, gangrene, and osteoarthropathy. These conditions necessitate minor or major amputation as part of treatment. In patients with Charcot's arthropathy and predominant neuropathy, recurrent foot ulcers are common in areas of high pressure. Such high pressure is caused by the degrading of the architecture of the foot and inadequate footwear. These patients are a clinical challenge. A select group of such patients may benefit from free surgical tissue transfer, though free or local flap surgery is often difficult or even impossible owing to an impaired arterial circulation. In such wounds, surgical debridement followed by skin grafts often fail due to bacterial burden in the wounds. To circumvent these problems, the authors developed a therapeutic approach using buried chip skin grafting to close granulation wound beds in diabetic feet. Locally applied vacuum therapy (VAC) for wound bed preparation of chronic, nonresponsive foot ulcers and subsequent grafting using the burying technique with a minute fraction of skin was used. Firm closure was achieved. The closed wound was resistant to mechanical irritation.
authors.affiliation: Department of Plastic and Hand Surgery, University Medical Center, Friedrich-Alexander-University Erlangen-Nürnberg, Germany. juergen.kopp@chir.imed.uni-erlangen.de
authors.forename: Jürgen
authors.initials: J
authors.lastname: Kopp
authors.forename: Ulrich
authors.initials: U
authors.lastname: Kneser
authors.forename: Alexander D
authors.initials: AD
authors.lastname: Bach
authors.forename: Raymund E
authors.initials: RE
authors.lastname: Horch