title: Brain stimulation in the treatment of epilepsy.
abstract: Stimulation of the brain for the treatment of epilepsy, indirectly via the vagus nerve and directly through intracranial targets, is feasible and has increased in use and complexity over the past 10 years. Vagus nerve stimulation is widely applied and the present indications and outcomes together with possible ways in which the treatment could be refined are reviewed. The application of stimulation to deep-brain targets is also reviewed along with present practice and results. Possible developments in the use of direct intracranial stimulation are also considered.
authors.affiliation: King's College, London Academic Neurosciences Centre, Institute of Psychiatry, De Crespigney Park, Denmark Hill, London, SE5 8AF, UK. polkeyce@aol.com
authors.forename: Charles E
authors.initials: CE
authors.lastname: Polkey
mesh_terms: D000818:Animals; D046690:Deep Brain Stimulation / Q000379:methods* / Q000639:trends; D004558:Electric Stimulation / Q000379:methods; D004827:Epilepsy / Q000628:therapy*; D005500:Follow-Up Studies; D006801:Humans; D017410:Practice Guidelines as Topic; D014630:Vagus Nerve / Q000502:physiology / Q000528:radiation effects