title: Ichthyosis uteri: a case report and review of the literature.
abstract: Squamous metaplasia of endometrium is mostly manifested by morules or nodules of benign nonkeratinizing squamous cells intimately mixed with benign or malignant endometrial glands. It has been described with low-grade adenocarcinoma of the endometrium, as well as with various benign conditions, including hyperplasia, chronic endometritis, and endometrial polyps. However, extensive plaquelike, keratinizing squamous change is distinctly uncommon. To our knowledge, we describe the first case of extensive benign squamous keratinization with underlying endometrial adenocarcinoma.
authors.affiliation: Department of Pathology, Creighton University Medical Center, Omaha, Neb 68131, USA. bewtra@pathology.creighton.edu
authors.forename: Chhanda
authors.initials: C
authors.lastname: Bewtra
authors.forename: Qing M
authors.initials: QM
authors.lastname: Xie
authors.forename: William J
authors.initials: WJ
authors.lastname: Hunter
authors.forename: William
authors.initials: W
authors.lastname: Jurgensen
mesh_terms: D000230:Adenocarcinoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D000368:Aged; D016889:Endometrial Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D007057:Ichthyosis / Q000175:diagnosis*; D007633:Keratins / Q000378:metabolism; D014599:Uterus / Q000378:metabolism / Q000473:pathology* / Q000601:surgery
chemical_list: D007633:Keratins