title: [Cardiac involvement in Kearns-Sayre syndrome].
abstract: The mitochondrial cytopathies or oxidative-phosphorylation diseases are a diverse group of disorders that result from the structural, biochemical, or genetic derangement of mitochondria. Because mitochondrial dysfunction can affect the most highly energy-dependent organs, cardiac involvement is frequent in these diseases. To identify the clinical features of Kearns-Sayre syndrome, an entity associated with this group of diseases, we evaluated cardiac structure and function in 5 patients with Kearns-Sayre syndrome and followed the clinical course of these patients for 5 years.
authors.affiliation: Departamento de Cardiología Intervencionista, Centro Hospitalario La Concepción, Saltillo, México. carlosfbarrera@yahoo.com
authors.forename: Carlos F
authors.initials: CF
authors.lastname: Barrera-Ramírez
authors.forename: Héctor M
authors.initials: HM
authors.lastname: Barragán-Campos
authors.forename: Hermes
authors.initials: H
authors.lastname: Ilarraza
authors.forename: Pedro
authors.initials: P
authors.lastname: Iturralde
authors.forename: María C
authors.initials: MC
authors.lastname: Avila-Casado
authors.forename: Jorge
authors.initials: J
authors.lastname: Oseguera
mesh_terms: D000328:Adult; D005260:Female; D006331:Heart Diseases / Q000209:etiology*; D006801:Humans; D007625:Kearns-Sayre Syndrome / Q000150:complications* / Q000175:diagnosis; D008297:Male