title: [Manifestations mimicking relapsing polychondritis in a patient with microscopic polyangiitis].
abstract: Microscopic polyangiitis (MPA) is a systemic disorder characterized by inflammation of small vessels mainly affecting the kidneys and lungs. We describe a 72-year-old woman who developed multiple cartilage involvements as well as major manifestations of MPA. The left ear biopsy demonstrated cartilaginous inflammation and small vessel vasculitis. She also had conjunctivitis, hearing impairment, interstitial lung disease, glomerulonephritis with vasculitis and mononeuritis multiplex. Serological examinations revealed a positive antineutrophil cytoplasmic antibody (PR-3 ANCA). Cyclophosphamide and oral corticosteroid therapy was instituted and remission achieved. Due to lacks of nasal and bronchial involvements, as well as the evidence of auricular vasculitis, we concluded that her findings mimicking relapsing polychondritis developed as systemic manifestations of MPA.
authors.affiliation: The Second Department of Internal Medicine, Saitama Medical Center.
authors.forename: Hiroe
authors.initials: H
authors.lastname: Ogawa
authors.forename: Eiko
authors.initials: E
authors.lastname: Nishi
authors.forename: Hideto
authors.initials: H
authors.lastname: Kameda
authors.forename: Koichi
authors.initials: K
authors.lastname: Amano
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Takeuchi
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis; D003520:Cyclophosphamide / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D011081:Polychondritis, Relapsing / Q000209:etiology* / Q000473:pathology; D011239:Prednisolone / Q000008:administration & dosage; D014657:Vasculitis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology
chemical_list: D000893:Anti-Inflammatory Agents; D019268:Antibodies, Antineutrophil Cytoplasmic; D003520:Cyclophosphamide; D011239:Prednisolone