title: [Gonadotropins and ovarian cancer].
abstract: The ovary is a tissue, which is sensitive to gonadotropins. Gonadotropins receptors are present in the epithelium and stroma of the ovary. Data from epidemiological study clearly shows, that development of tumor is correlated with morphological and biochemical processes taking place in the gonad. The role of gonadotropins, as well as the role of their receptors in the proliferation of the ovarian tissue was shown. Further research is needed to explain the molecular mechanism of gonadotropin activity in ovarian tissue, however the important role of gonadotropins in the pathology of ovarian tissue is already well established.
authors.affiliation: Klinika Onkologii Ginekologicznej, AM im Karola Marcinkowskiego w Poznaniu.
authors.forename: Ewa
authors.initials: E
authors.lastname: Nowak-Markwitz
authors.forename: Anna
authors.initials: A
authors.lastname: Jankowska
authors.forename: Marek
authors.initials: M
authors.lastname: Spaczyński
mesh_terms: D049109:Cell Proliferation; D006063:Chorionic Gonadotropin / Q000378:metabolism*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism; D006062:Gonadotropins / Q000378:metabolism; D006801:Humans; D007986:Luteinizing Hormone / Q000378:metabolism; D010051:Ovarian Neoplasms / Q000378:metabolism*; D011962:Receptors, FSH / Q000378:metabolism; D011967:Receptors, Gonadotropin / Q000378:metabolism; D011974:Receptors, LH / Q000378:metabolism
chemical_list: D006063:Chorionic Gonadotropin; D006062:Gonadotropins; D011962:Receptors, FSH; D011967:Receptors, Gonadotropin; D011974:Receptors, LH; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone