title: Terbium sensitized determination of tosufloxacin using electrochemiluminescence method.
abstract: A novel method for determination of trace amounts of tosufloxacin (TFLX) based on electrochemiluminescence (ECL) has been developed. The calibration graphs for TFLX were linear in the range of 5.0 x 10(-11)-3.5 x 10(-7) mol/L, with the detection limit of 1.3 x 10(-11) mol/L. Key factors affecting the determination of TFLX were investigated. TFLX amounts in capsule and serum samples were successfully detected by this method. A possible mechanism of energy transfer, and thus the explanation of ECL in the Tb3+-TFLX-Na2S2O4 system are discussed.
authors.affiliation: Department of Chemistry, Beijing Normal University, Beijing 100875, PR China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
authors.forename: Shilv
authors.initials: S
authors.lastname: Chen
authors.forename: Huichun
authors.initials: H
authors.lastname: Zhao
authors.forename: Linpei
authors.initials: L
authors.lastname: Jin
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis*; D002138:Calibration; D002214:Capsules; D004563:Electrochemistry; D024841:Fluoroquinolones / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D008163:Luminescent Measurements; D009287:Naphthyridines / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet; D013725:Terbium / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D002214:Capsules; D024841:Fluoroquinolones; D007202:Indicators and Reagents; D009287:Naphthyridines; D013725:Terbium; C055185:tosufloxacin