title: One-pot Friedel-Crafts/Robinson-Gabriel synthesis of oxazoles using oxazolone templates.
abstract: [reaction: see text] We report herein a one-pot synthesis of 2,4,5-trisubstituted oxazoles via a Friedel-Crafts/Robinson-Gabriel synthesis using a general oxazolone template. Treatment of the oxazolone template with a range of aromatic nucleophiles provided the highly substituted oxazoles in good yields.
authors.affiliation: Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, USA.
authors.forename: Manasi
authors.initials: M
authors.lastname: Keni
authors.forename: Jetze J
authors.initials: JJ
authors.lastname: Tepe