title: [Expression of L-selectin on the surface of neutrophils stimulated by TNF-alpha and level of sL-selectin in serum of patients with lung cancer].
abstract: The aim of the study was to estimate L-selectin expression on peripheral blood PMN stimulated by TNF-alpha and concentration of a soluble form of L-selectin in serum of patients with small cell and non-small cell lung cancer. The results showed an increased expression of L-selectin on PMN isolated from peripheral blood and an elevated concentration of sL-selectin in serum of patients with small cell and non-small cell lung cancer. An increased expression of these adhesion molecules may be the result of neutrophil activation by inflammatory cytokines.
authors.affiliation: Zaklad Immunologii Akademii Medycznej w Białymstoku
authors.forename: Aneta
authors.initials: A
authors.lastname: Izycka
authors.forename: Ewa
authors.initials: E
authors.lastname: Jabłońska
authors.forename: Tomasz
authors.initials: T
authors.lastname: Izycki
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Chyczewska
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000097:blood*; D018288:Carcinoma, Small Cell / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D019041:L-Selectin / Q000097:blood*; D008175:Lung Neoplasms / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000378:metabolism*; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
chemical_list: D014409:Tumor Necrosis Factor-alpha; D019041:L-Selectin