title: Developmental-stage-specific assembly of ParB complexes in Streptomyces coelicolor hyphae.
abstract: In Streptomyces coelicolor ParB is required for accurate chromosome partitioning during sporulation. Using a functional ParB-enhanced green fluorescent protein fusion, we observed bright tip-associated foci and other weaker, irregular foci in S. coelicolor vegetative hyphae. In contrast, in aerial hyphae regularly spaced bright foci accompanied sporulation-associated chromosome condensation and septation.
authors.affiliation: John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, United Kingdom. dagmara.jakimowicz@bbsrc.ac.uk
authors.forename: Dagmara
authors.initials: D
authors.lastname: Jakimowicz
authors.forename: Bertolt
authors.initials: B
authors.lastname: Gust
authors.forename: Jolanta
authors.initials: J
authors.lastname: Zakrzewska-Czerwinska
authors.forename: Keith F
authors.initials: KF
authors.lastname: Chater
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D004815:Epidermal Growth Factor / Q000235:genetics; D019077:Helix-Turn-Helix Motifs; D025301:Hyphae / Q000502:physiology*; D025282:Mycelium / Q000502:physiology; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism; D013171:Spores, Bacterial / Q000502:physiology; D048372:Streptomyces coelicolor / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D011993:Recombinant Fusion Proteins; C052883:chromosome partition proteins, bacterial; D004815:Epidermal Growth Factor