title: Biological effect of 1-dodecanol in teneral and post-teneral Rhodnius prolixus and Triatoma infestans (Hemiptera: Reduviidae).
abstract: Topical application of 1-dodecanol was significantly more toxic against teneral first nymphs (1-3 h old) than post-teneral first nymphs (24 h old). The lethal dose ratios were 711,500 for Rhodnius prolixus and 3613 for Triatoma infestans. No significative difference between LD50 was found when 1-dodecanol was injected in recently hatched adult R. prolixus (1-4 h old) nor in older adults (24 h old). These values were similar to those calculated for deltamethrin (an effective triatomicide), showing that 1-dodecanol had no insecticidal properties when it was applied by injection. Topical application of high dose of 1-dodecanol (1 microg/i) on teneral first nymphs of R. prolixus, produced an interruption of the darkening process of the cuticle, and probably in the development of its physiological properties.
authors.affiliation: Centro de Investigaciones de Plagas e Insecticidas, Juan Bautista de la Salle 4397 (B1603ALO), Villa Martelli, Buenos Aires, Argentina. gmougabure@citefa.gov.ar
authors.forename: Gastón Mougabure
authors.initials: GM
authors.lastname: Cueto
authors.forename: Eduardo
authors.initials: E
authors.lastname: Zerba
authors.forename: María Inés
authors.initials: MI
authors.lastname: Picollo
mesh_terms: D000818:Animals; D007851:Dodecanol / Q000494:pharmacology*; D007306:Insecticides / Q000494:pharmacology*; D007928:Lethal Dose 50; D009758:Nymph / Q000187:drug effects; D012239:Rhodnius / Q000187:drug effects*; D013997:Time Factors; D014224:Triatoma / Q000187:drug effects*
chemical_list: D007306:Insecticides; D007851:Dodecanol