title: [Expression of c-FOS protein in rat hippocampus by inducing of mercury contaminated rice].
abstract: In order to probe into the biological effects of mercury in typical mercury contaminated area and try to apply the expression of immediately early gene c-fos in brain to early predict the neurotoxicity of mercury in typical polluted areas, the expression of c-FOS protein in rat hippocampus is observed using immunocytochemical methods. The results show the mercury pollutes rice induced significantly the expression of c-FOS protein in hippccampus;the antagonisis between selenium and mercury on the exposure process. It is suggested that c-fos can be used as an effective index of detecting and assessing neurotoxicology of mercury polluted areas.
authors.affiliation: School of Environmental Science and Engineering, Shanghai Jiaotong University, Shanghai 200240, China.
authors.forename: Jin-ping
authors.initials: JP
authors.lastname: Cheng
authors.forename: Wen-hua
authors.initials: WH
authors.lastname: Wang
authors.forename: Li-ya
authors.initials: LY
authors.lastname: Qu
authors.forename: Jin-ping
authors.initials: JP
authors.lastname: Jia
authors.forename: Min
authors.initials: M
authors.lastname: Zheng
mesh_terms: D000818:Animals; D005260:Female; D005506:Food Contamination / Q000032:analysis*; D006624:Hippocampus / Q000378:metabolism*; D008297:Male; D008628:Mercury / Q000633:toxicity*; D012275:Oryza; D016760:Proto-Oncogene Proteins c-fos / Q000096:biosynthesis* / Q000235:genetics; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D016760:Proto-Oncogene Proteins c-fos; D008628:Mercury