title: Echocardiographic examination of atrioventricular and interventricular delay optimization in cardiac resynchronization therapy.
abstract: In 21 patients implanted with a biventricular pacing device with programmable interventricular delay (VVd), the myocardial performance index (MPI) was evaluated during spontaneous sinus rhythm, simultaneous biventricular pacing, and sequential biventricular pacing at different VVds and atrioventricular delays (AVds). The AVd-VVd combination associated with the minimum MPI defined patient-tailored biventricular pacing. Simultaneous biventricular pacing significantly improved MPI compared with spontaneous sinus rhythm. An additional improvement was obtained by tailored biventricular pacing. The optimal AVds were significantly shorter during right ventricular preactivation than during left ventricular preactivation.
authors.affiliation: Division of Cardiology, Careggi Hospital, Florence, Italy. c.porciani@dac.unifi.it
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Porciani
authors.forename: Cristina
authors.initials: C
authors.lastname: Dondina
authors.forename: Roberto
authors.initials: R
authors.lastname: Macioce
authors.forename: Gabriele
authors.initials: G
authors.lastname: Demarchi
authors.forename: Paolo
authors.initials: P
authors.lastname: Pieragnoli
authors.forename: Nicola
authors.initials: N
authors.lastname: Musilli
authors.forename: Andrea
authors.initials: A
authors.lastname: Colella
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Ricciardi
authors.forename: Antonio
authors.initials: A
authors.lastname: Michelucci
authors.forename: Luigi
authors.initials: L
authors.lastname: Padeletti
mesh_terms: D000208:Acute Disease; D000368:Aged; D001283:Atrioventricular Node / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002037:Bundle-Branch Block / Q000000981:diagnostic imaging / Q000628:therapy*; D002304:Cardiac Pacing, Artificial; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D008297:Male; D013599:Systole / Q000502:physiology*; D013997:Time Factors; D016896:Treatment Outcome; D014463:Ultrasonography; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000628:therapy*