title: Clade, Country and Region-specific HIV-1 Vaccines: Are they necessary?
abstract: Today, scientists are often encouraged to custom-design vaccines based on a particular country or clade. Here, we review the scientific literature and then suggest that the overwhelming endeavor to produce a unique vaccine for every world region or virus subtype may not be necessary.
authors.affiliation: Department of Infectious Diseases, St Jude Children's Research Hospital, 332 N, Lauderdale, Memphis, TN 38105 USA. julia.hurwitz@stjude.org.
authors.forename: Karen S
authors.initials: KS
authors.lastname: Slobod
authors.forename: Chris
authors.initials: C
authors.lastname: Coleclough
authors.forename: Scott A
authors.initials: SA
authors.lastname: Brown
authors.forename: John
authors.initials: J
authors.lastname: Stambas
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Zhan
authors.forename: Sherri
authors.initials: S
authors.lastname: Surman
authors.forename: Bart G
authors.initials: BG
authors.lastname: Jones
authors.forename: Amy
authors.initials: A
authors.lastname: Zirkel
authors.forename: Pamela J
authors.initials: PJ
authors.lastname: Freiden
authors.forename: Brita
authors.initials: B
authors.lastname: Brown
authors.forename: Robert
authors.initials: R
authors.lastname: Sealy
authors.forename: Mattia
authors.initials: M
authors.lastname: Bonsignori
authors.forename: Julia L
authors.initials: JL
authors.lastname: Hurwitz