[Raman spectra of cell from breast cancer patients].
Raman spectra of normal and cancer cell from breast cancer patients a represented. It is reported that all of the Ramanlines become weak. The intensities of Raman lines 782 and 1 084 cm(-1) of DNA phosphate group and 1 155 and 1 262 cm(-1) of deoxyribosephosphate decrease. The spectral lines 812 cm(-1) of A-type DNA and 979 and 668 cm(-1) disappear, and the 905 cm(-1) peak is shifted to lower frequency by 6 cm(-1). This means that the phosphate backbone of DNA is destroyed to a certain extent and the fissiparity of cancer cell can't be controlled effectively. In addition, the authors found a kind of Raman line 960 cm(-1) concerning calcificationand sclerosis of cancer cell. The results indicate that Raman spectra may offer the experiment basis for the cancer diagnosis and treatment.
Yan
Xun-Ling
XL
School of Physics Science and Information Engineering, Liaocheng University, Liaocheng 252059, China.
Dong
Rui-Xin
RX
Wang
Qiu-Guo
QG
Chen
Shuang-Feng
SF
Zhang
Zong-Wang
ZW
Zhang
Xue-Jun
XJ
Zhang
Lei
L
D001943:Breast Neoplasms / Q000378:metabolism / Q000473:pathology*; D002114:Calcinosis / Q000175:diagnosis; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D006801:Humans; D012598:Sclerosis / Q000175:diagnosis; D013059:Spectrum Analysis, Raman
D004273:DNA, Neoplasm