title: Cyclobutane dimers from the Colombian medicinal plant Achyrocline bogotensis.
abstract: Five cyclobutane dimers, achyrodimers A-E (1-5), along with 11 known compounds were isolated from the methanol extract of the Colombian medicinal plant Achyrocline bogotensis. Their structures were elucidated by spectroscopy. Several of these compounds were screened for cytokine-inducing activity in human peripheral blood mononuclear cells.
authors.affiliation: Graduate School of Pharmaceutical Sciences, University of Tokushima, Sho-machi, Tokushima 770-8505, Japan.
authors.forename: Takaaki
authors.initials: T
authors.lastname: Sagawa
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Takaishi
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Fujimoto
authors.forename: Carmenza
authors.initials: C
authors.lastname: Duque
authors.forename: Coralia
authors.initials: C
authors.lastname: Osorio
authors.forename: Freddy
authors.initials: F
authors.lastname: Ramos
authors.forename: Cristina
authors.initials: C
authors.lastname: Garzon
authors.forename: Mitsunobu
authors.initials: M
authors.lastname: Sato
authors.forename: Masato
authors.initials: M
authors.lastname: Okamoto
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Oshikawa
authors.forename: Sharif Uddin
authors.initials: SU
authors.lastname: Ahmed
mesh_terms: D036921:Achyrocline / Q000737:chemistry*; D003105:Colombia; D003503:Cyclobutanes / Q000097:blood / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016207:Cytokines / Q000096:biosynthesis; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D003503:Cyclobutanes; D016207:Cytokines