The gene of the complement-binding protein, an important anti-inflammatory factor of orthopoxviruses, is deleted from the genome of Western African strains of monkeypox virus.
Uvarova
E A
EA
Vector Scientific and Research Center of Virology and Biotechnology, Kol'tsovo, Novosibirsk oblast, 630559 Russia.
Totmenin
A V
AV
Sandakhchiev
L S
LS
Shchelkunov
S N
SN
D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D002352:Carrier Proteins / Q000235:genetics; D003169:Complement Inactivator Proteins / Q000737:chemistry / Q000378:metabolism; D003165:Complement System Proteins / Q000378:metabolism; D004587:Electrophoresis, Agar Gel; D017353:Gene Deletion; D005814:Genes, Viral; D006801:Humans; D008957:Models, Genetic; D008993:Monkeypox virus / Q000235:genetics*; D018155:Orthopoxvirus / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011213:Poxviridae Infections / Q000378:metabolism / Q000821:virology; D014176:Protein Biosynthesis; D011951:Receptors, Complement / Q000235:genetics*; D014764:Viral Proteins / Q000235:genetics* / Q000502:physiology*
D000893:Anti-Inflammatory Agents; D002352:Carrier Proteins; D003169:Complement Inactivator Proteins; D011951:Receptors, Complement; D014764:Viral Proteins; D003165:Complement System Proteins