title: Recent advances in asymmetric synthesis of pipecolic acid and derivatives.
abstract: This review covers the literature relating to asymmetric syntheses of pipecolic acid derivatives from 1997 to present. This review is organized according to the position and the degree of substitution of the piperidinic cycle. In a first section, syntheses of pipecolic acid itself are described. Then, successively, syntheses of C-3, C-4, C-5, C-6 substituted pipecolic acid derivatives are reported. Finally, syntheses of unsaturated pipecolic acid derivatives are presented before the last part devoted to the polysubstituted pipecolic acid derivatives.
authors.affiliation: Laboratoire de Chimie Organique, CNRS/UMR 7611, Université Pierre et Marie Curie, Case 47, Paris, France. kadouri@ccr.jussieu.fr
authors.forename: C
authors.initials: C
authors.lastname: Kadouri-Puchot
authors.forename: S
authors.initials: S
authors.lastname: Comesse
mesh_terms: D000605:Amino Alcohols / Q000737:chemistry; D048289:Imidazolidines / Q000737:chemistry; D007783:Lactones / Q000737:chemistry; D010777:Photochemistry; D010875:Pipecolic Acids / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D000605:Amino Alcohols; D048289:Imidazolidines; D007783:Lactones; D010875:Pipecolic Acids; C031345:pipecolic acid