Islet isolation and transplantation from an annular pancreas: a case report.
BACKGROUND
Annular pancreas is an uncommon congenital anomaly formed by a thin band of normal pancreatic tissue encircling the duodenum.


METHODS
We report the first case of an islet isolation and transplantation from an annular pancreas. The pancreas together with duodenum was procured from a 32-year-old previously healthy man after diagnosis of brain death. The pancreas including the annular portion was distended well after intraductal collagenase perfusion. A total of 276,064 islet equivalent was recovered and transplanted into a type 1 diabetic patient.


CONCLUSIONS
Bearing in mind the shortage of donors, patients with this anomalous condition should not be excluded as potential organ donors.
Kin
Tatsuya
T
Clinical Islet Transplant Program, University of Alberta and Capital Health Authority, Edmonton, Alberta, Canada.
Shapiro
James
J
Ryan
Edmond A
EA
Lakey
Jonathan R T
JR
D000328:Adult; D001926:Brain Death; D002469:Cell Separation; D003922:Diabetes Mellitus, Type 1 / Q000601:surgery; D004386:Duodenum / Q000033:anatomy & histology; D006801:Humans; D007515:Islets of Langerhans / Q000166:cytology*; D016381:Islets of Langerhans Transplantation; D008297:Male; D010179:Pancreas / Q000002:abnormalities*; D009927:Tissue and Organ Procurement