Inhibition studies on salicylate synthase.
Analogues of chorismate and isochorismate were designed and tested as potential inhibitors in the first inhibition study against a salicylate synthase.
Payne
Richard J
RJ
University of Cambridge, Department of Chemistry, Lensfield Road, Cambridge, UK CB2 1EW.
Kerbarh
Olivier
O
Miguel
Ricardo Nunez
RN
Abell
Andrew D
AD
Abell
Chris
C
D001419:Bacteria / Q000201:enzymology; D002827:Chorismic Acid / Q000737:chemistry / Q000494:pharmacology*; D053138:Cyclohexenes; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D008190:Lyases / Q000037:antagonists & inhibitors* / Q000737:chemistry; D008958:Models, Molecular
D053138:Cyclohexenes; D004791:Enzyme Inhibitors; C052985:isochorismic acid; D008190:Lyases; C022620:salicylate synthetase; D002827:Chorismic Acid