title: Systemic vasodilation is a predominant cause of hypotension in a patient with familial amyloid polyneuropathy during liver transplantation.
abstract: A patient with familial amyloid polyneuropathy underwent a living, nonrelated orthotopic liver transplant and developed hypotension after induction of anesthesia. Causes of hypotension in patients with familial amyloid polyneuropathy are discussed. Transesophageal echocardiographic monitoring was invaluable in differentiating various causes of hypotension and in diagnosing peripheral vasodilation as the predominant cause of hypotension.
authors.affiliation: Department of Anesthesiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. gneelakanta@mednet.ucla.edu
authors.forename: Gundappa
authors.initials: G
authors.lastname: Neelakanta
authors.forename: Aman
authors.initials: A
authors.lastname: Mahajan
authors.forename: Cynthia
authors.initials: C
authors.lastname: Antin
mesh_terms: D000328:Adult; D028227:Amyloid Neuropathies, Familial / Q000150:complications; D000758:Anesthesia / Q000009:adverse effects*; D017548:Echocardiography, Transesophageal; D006439:Hemodynamics; D006801:Humans; D007022:Hypotension / Q000209:etiology / Q000503:physiopathology; D017093:Liver Failure / Q000209:etiology / Q000601:surgery*; D016031:Liver Transplantation / Q000009:adverse effects*; D019520:Living Donors; D008297:Male; D014664:Vasodilation / Q000502:physiology