Clinical quiz: a pediatric case presenting with fever and diffuse myalgia.
Familial Mediterranean fever (FMF) is a multisystem disease characterized by recurrent polyserositis episodes seen in certain ethnic groups. In recent years the clinical picture of FMF has been expanded and severe myalgia is a frequently recognized component of the syndrome. Protracted febrile myalgia syndrome (PFMS), characterized by severe paralyzing myalgia, high fever, abdominal pain, diarrhea, arthritis/arthralgia, and transient vasculitic rashes mimicking Henoch-Schonlein purpura, was first described in patients with FMF in 1994. We describe an 11-year-old Turkish girl with a second attack of PFMS before being diagnosed as having FMF, emphasizing the importance of myalgia for the diagnosis of FMF even in the absence of other symptoms.
Soylu
Alper
A
Department of Pediatrics, Dokuz Eylül University Medical Faculty, Inciralti, Izmir, Turkey.
Oztürk
Yeşim
Y
Kasap
Belde
B
Akman
Nilüfer
N
Türkmen
Mehmet
M
Kavukçu
Salih
S
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002648:Child; D010505:Familial Mediterranean Fever / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D009135:Muscular Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D010146:Pain / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D011239:Prednisolone / Q000627:therapeutic use; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D011239:Prednisolone