Analgesic and anti-inflammatory activity of Leonurus sibiricus.
The methanolic extract of Leonurus sibiricus aerial parts injected intraperitoneally at dose of 250 and 500 mg/kg showed a significant analgesic effect in acetic acid-induced writhing in mice. Moreover, when given orally to rats at dose of 200 and 400 mg/kg, it showed a significant anti-inflammatory activity against carrageenin induced rat paw edema in rats.
Islam
M Amirul
MA
Pharmacy Discipline, Khulna University, Khulna-9208, Bangladesh.
Ahmed
Firoj
F
Das
A K
AK
Bachar
S C
SC
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D004487:Edema / Q000188:drug therapy; D005260:Female; D031332:Leonurus / Q000737:chemistry*; D008297:Male; D051379:Mice; D010146:Pain / Q000188:drug therapy; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats
D000894:Anti-Inflammatory Agents, Non-Steroidal; D010936:Plant Extracts