title: [Treatment of cutaneous metastases of a squamous cell carcinoma of the leg with topical miltefosine].
abstract: BACKGROUND
  Miltefosine (Hexadecylphosphocholine) is a chemotherapy, which when applied locally, has demonstrated efficacy in the treatment of cutaneous metastases of breast cancer.
  
  
  METHODS
  A 79 year-old woman developed recurrent in transit cutaneous metastases of a squamous cell carcinoma on her left leg. All lesions completely resolved after topical applications of miltefosine. Tolerance was excellent and the patient remained disease-free 24 months after the end of the treatment.
  
  
  CONCLUSIONS
  Miltefosine, which might prove to be a simple and effective alternative for the usually heavy treatments proposed, warrants further assessment in this context.
authors.affiliation: Service de Dermatologie, Hôpital Sainte-Marguerite, Marseille.
authors.forename: L
authors.initials: L
authors.lastname: Mahieu-Renard
authors.forename: M-A
authors.initials: MA
authors.lastname: Richard
authors.forename: J-P
authors.initials: JP
authors.lastname: Dales
authors.forename: S
authors.initials: S
authors.lastname: Buscaylet
authors.forename: S
authors.initials: S
authors.lastname: Lagrassa
authors.forename: J-J
authors.initials: JJ
authors.lastname: Grob
mesh_terms: D000287:Administration, Topical; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000556:secondary*; D005260:Female; D006801:Humans; D007866:Leg; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy*; D010767:Phosphorylcholine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000556:secondary*
chemical_list: D000970:Antineoplastic Agents; D010767:Phosphorylcholine; C039128:miltefosine