title: Technetium-99m diphosphonate imaging of psammocarcinoma of probable ovarian origin: case report and literature review.
abstract: Technetium-99m methylene diphosphonate (Tc-99m MDP) bone scans have long been used by clinicians to diagnose osseous metastases in patients with cancer. However, in several benign and malignant diseases, notably those characterized by extensive soft tissue calcification, Tc-99m MDP may be taken up by the tumor itself. We present a case of a stage IIIC psammoma-rich low-grade serous carcinoma of the ovary, whose identity and extent of disease were first suggested by Tc-99m MDP scintigraphy. The literature concerning this form of cancer, and the use of Tc-99m MDP bone scans to image soft tissue lesions, are reviewed.
authors.affiliation: Hematology & Medical Oncology Division, Department of Internal Medicine, St. Vincent's Catholic Medical Centers of New York, 170 West 11th Street, New York, NY 10019, USA.
authors.forename: Arthur I
authors.initials: AI
authors.lastname: Radin
authors.forename: Irini M
authors.initials: IM
authors.lastname: Youssef
authors.forename: Ricardo D
authors.initials: RD
authors.lastname: Quimbo
authors.forename: Robert W
authors.initials: RW
authors.lastname: Perone
authors.forename: Claudio
authors.initials: C
authors.lastname: Guerrieri
authors.forename: Hussein M
authors.initials: HM
authors.lastname: Abdel-Dayem
mesh_terms: D018284:Cystadenocarcinoma, Serous / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000556:secondary*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography / Q000379:methods; D019275:Radiopharmaceuticals; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000556:secondary*; D013669:Technetium Tc 99m Medronate
chemical_list: D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate