title: Determination of the concentration scaling law of the scattering coefficient of water solutions of Intralipid at 832 nm by comparison between collimated detection measurements and Monte Carlo simulations.
abstract: OBJECTIVE
  Intralipid (IP) is a scatterer extensively used in the building of phantoms for Biomedical Optics measurements. Recently, deviations from the linearity have been shown for the concentration scaling law of the scattering coefficient of IP water solutions at visible wavelengths. In this work this scaling law was determined at 832 nm.
  
  
  METHODS
  Space resolved transmittance measurements of a laser beam at 832 nm through water solutions of IP and ink were performed and compared with the corresponding results of Monte Carlo simulations.
  
  
  RESULTS
  The comparison provides a quadratic dependence of mu'(s) on the volume-to-volume scatterer concentration, C(IP), in the range of C(IP) values (0.0024<C(IP)<0.0075). These deviations from the linear behavior are related to the failure of the independent scatterer approximation.
  
  
  CONCLUSIONS
  The quadratic dependence of mu'(s) on C(IP) is in agreement with recent results obtained by other groups with different experimental techniques and is validated by a recent theoretical work.
authors.affiliation: Dipartimento di Scienze Fisiche, Università di Napoli Federico II, Napoli I-80126, Italy.
authors.forename: Maddalena
authors.initials: M
authors.lastname: Autiero
authors.forename: Raffaele
authors.initials: R
authors.lastname: Liuzzi
authors.forename: Patrizia
authors.initials: P
authors.lastname: Riccio
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Roberti
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005217:Fat Emulsions, Intravenous / Q000737:chemistry* / Q000528:radiation effects; D007281:Ink; D007834:Lasers; D008956:Models, Chemical; D009010:Monte Carlo Method; D016011:Normal Distribution; D012542:Scattering, Radiation; D012996:Solutions; D014867:Water / Q000737:chemistry*
chemical_list: D005217:Fat Emulsions, Intravenous; D012996:Solutions; D014867:Water