Acute mania in the setting of severe hypothyroidism.
Although the associations between depression and hypothyroidism and between mania and hyperthyroidism are well described, mania in the setting of hypothyroidism is unusual. The authors present the case of a patient whose acute mania appears to have been precipitated by hypothyroidism secondary to postpartum thyroiditis. This case underscores the importance of thyroid screening in patients with mood and psychotic disorders, including patients who lack the classical psychiatric features of thyroid dysfunction. Further investigation is required on the nature of the relationship between thyroid function and bipolar disorder and any implications it may have for the diagnosis and treatment of this illness.
Stowell
Charles P
CP
Department of Psychiatry, New York-Presbyterian Hospital, Weill-Cornell Medical Center, 525 East 68th St., New York, NY 10021, USA. chs9017@nyp.org
Barnhill
John W
JW
D000208:Acute Disease; D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy / Q000453:epidemiology*; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology; D018967:Risperidone / Q000627:therapeutic use; D012720:Severity of Illness Index; D013961:Thyroid Gland / Q000503:physiopathology; D013974:Thyroxine / Q000627:therapeutic use
D014150:Antipsychotic Agents; D018967:Risperidone; D013974:Thyroxine