Ionic liquid as reagent. A green procedure for the regioselective conversion of epoxides to vicinal-halohydrins using [AcMIm]X under catalyst- and solvent-free conditions.
A variety of structurally diverse epoxides undergo facile cleavages by ionic liquid, [AcMIm]X without any catalyst and solvent to produce the corresponding vicinal halohydrins in high yields. The cleavages are considerably fast and highly regioselective.
Ranu
Brindaban C
BC
Department of Organic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700 032, India. ocbcr@iacs.res.in
Banerjee
Subhash
S
D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods; D004852:Epoxy Compounds / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D015394:Molecular Structure; D013237:Stereoisomerism
D004852:Epoxy Compounds; D006846:Hydrocarbons, Halogenated; D007202:Indicators and Reagents