Hypopituitarism as a late complication of hemorrhagic fever.
We report three patients who developed hypopituitarism as a late complication of hemorrhagic fever with renal syndrome (HFRS). Their past history, physical examination, and endocrine investigation confirmed hypopituitarism. Magnetic resonance imaging of the pituitary revealed atrophic pituitary gland with an empty sella. Hemorrhagic fever is endemic in certain regions of the Balkans, and this preliminary report suggests the importance of investigating the endocrine status in every patient who survived HFRS.
Pekic
Sandra
S
Institute of Endocrinology, Diabetes and Diseases of Metabolism, University Clinical Center, Belgrade, Serbia.
Cvijovic
Goran
G
Stojanovic
Marko
M
Kendereski
Aleksandra
A
Micic
Dragan
D
Popovic
Vera
V
D000328:Adult; D018063:Hantaan virus / Q000254:growth & development*; D006480:Hemorrhagic Fever with Renal Syndrome / Q000150:complications*; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology* / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged