title: Information overload--new technologies, can we store the data?
abstract: Computerization within newborn screening programs is a developing issue. To date two basic approaches to data storage have been used: (1) a storage system for babies diagnosed with a disorder, (2) a comprehensive system with long-term details for all patient samples, tests performed, test results and interpretations. It usually provides efficient real-time reports for various clinical and quality control requirements and easy access to an inborn errors registry. Within the last decade there have been two new technologies adapted to routine use in newborn screening laboratories: (1) tandem mass spectrometry for selected amino acids and acyl carnitine, and (2) DNA mutational analysis of PCR products. Both technologies present data storage challenges. Both are capable of providing large files of information for a sample. Consideration must be given to how these data are stored, whether all results including a graphical representation or DNA sequence data are kept or whether only final results for specific analytes are stored. Many new analytical technologies can only be incorporated into routine programs as a result of advances in hardware and software allowing better access to, and storage of, data.
authors.affiliation: The NSW Newborn Screening Program The Children's Hospital at Westmead, Sydney, NSW, Australia.
authors.forename: Veronica
authors.initials: V
authors.lastname: Wiley
authors.forename: Kevin
authors.initials: K
authors.lastname: Carpenter
authors.forename: Bruce
authors.initials: B
authors.lastname: Bennetts
authors.forename: Bridget
authors.initials: B
authors.lastname: Wilcken
mesh_terms: D001315:Australia; D002984:Clinical Laboratory Information Systems; D004247:DNA / Q000032:analysis; D003628:Database Management Systems; D030541:Databases, Genetic; D005821:Genetic Techniques; D006801:Humans; D007231:Infant, Newborn; D016247:Information Storage and Retrieval; D008661:Metabolism, Inborn Errors / Q000175:diagnosis* / Q000235:genetics; D015997:Neonatal Screening / Q000458:organization & administration*; D012042:Registries
chemical_list: D004247:DNA