Palladium catalysed enantioselective phosphination reactions using secondary phosphine-boranes and aryl iodide.
Preliminary results dealing with the enantioselective version of the C-P cross-coupling reaction between dissymmetric secondary phosphine-borane complexes and aryl iodide derivatives are presented. To gain information on the enantiodiscriminating step, direct observation of an intermediate involved in the catalytic cycle has been achieved by (31)P NMR spectroscopy.
Pican
Stephanie
S
Laboratoire de Chimie Moleculaire et Thio-organique, UMR CNRS 6507, ENSICAEN, Universite de Caen, 6 bd du Marechal Juin, 14050 Caen, France.
Gaumont
Annie-Claude
AC
D001880:Boranes / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D006847:Hydrocarbons, Iodinated / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008958:Models, Molecular; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D009943:Organophosphorus Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D010759:Phosphorus Isotopes; D012680:Sensitivity and Specificity; D013237:Stereoisomerism
D001880:Boranes; D006847:Hydrocarbons, Iodinated; D009942:Organometallic Compounds; D009943:Organophosphorus Compounds; D010720:Phosphines; D010759:Phosphorus Isotopes; D010165:Palladium; C044646:phosphine