Traditional aqueous kava extracts inhibit cytochrome P450 1A2 in humans: Protective effect against environmental carcinogens?
Russmann
Stefan
S
Lauterburg
Bernhard H
BH
Barguil
Yann
Y
Choblet
Erwan
E
Cabalion
Pierre
P
Rentsch
Katharina
K
Wenk
Markus
M
D002274:Carcinogens, Environmental / Q000009:adverse effects*; D019388:Cytochrome P-450 CYP1A2 / Q000187:drug effects / Q000378:metabolism; D065609:Cytochrome P-450 CYP1A2 Inhibitors; D005260:Female; D005544:Forecasting; D006801:Humans; D020901:Kava / Q000737:chemistry*; D008297:Male; D008518:Medicine, East Asian Traditional; D009510:New Caledonia / Q000208:ethnology; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000493:pharmacokinetics*; D012646:Self Administration; D013997:Time Factors; D015854:Up-Regulation; D014867:Water
D002274:Carcinogens, Environmental; D065609:Cytochrome P-450 CYP1A2 Inhibitors; D010936:Plant Extracts; D014867:Water; D019388:Cytochrome P-450 CYP1A2