title: [Dead time determination of the second dimension in a comprehensive two-dimensional gas chromatography].
abstract: Comprehensive two-dimensional gas chromatography (GC x GC) is rapidly gaining importance for the analysis of complex samples. In order to predict chromatogram and optimize the operational conditions, the dead time of each dimension should be obtained exactly. Two methods to calculate the dead time of the second dimension were introduced. In the first method, based on the relationship between the time differences of a series of n-alkanes substances and the apparent retention times under different pressures, the true retention time can be calculated for non-synchronous GC x GC. The retention times of homologous series were used to calculate the dead time. Another rapid method to calculate the dead time of the second dimension is based on three or more apparent retention times in a single temperature programmed chromatographic run. The results show that the dead time of the second dimension can be calculated successfully by using the proposed methods and the deviation between the two methods is less than 0.05 s.
authors.affiliation: National Chromatographic R. & A. Center, Dalian Institute of Chemical Physics, The Chinese Academy of Sciences, Dalian 116011, China.
authors.forename: Hongwei
authors.initials: H
authors.lastname: Kong
authors.forename: Fen
authors.initials: F
authors.lastname: Ye
authors.forename: Xin
authors.initials: X
authors.lastname: Lu
authors.forename: Mingquan
authors.initials: M
authors.lastname: Dong
authors.forename: Lei
authors.initials: L
authors.lastname: Guo
authors.forename: Guowang
authors.initials: G
authors.lastname: Xu
mesh_terms: D000465:Algorithms; D000473:Alkanes / Q000032:analysis*; D002849:Chromatography, Gas / Q000295:instrumentation / Q000379:methods*; D008956:Models, Chemical; D011312:Pressure; D013696:Temperature; D013997:Time Factors
chemical_list: D000473:Alkanes