title: [Betamethasone injection in chronic hypertrophic laryngitis].
abstract: OBJECTIVE
  To evaluate the curative effects of Betamethasone for treatment of voice hoarseness of chronic hypertrophic laryngitis.
  
  
  METHODS
  From July, 2001 to December, 2002, 48 cases of the chronic hypertrophic laryngitis had been treated by injected of Betamethasone at vocal cords. Fundamental frequency (FO), jitter, shimmer, normalized noise energy (NNE) acoustics' parameters were tested and paired t test were calculated. The voice quality of 1 month and 6 months after treatment were synthetically graded, one-way ANOVA and the DANCAN test were conducted.
  
  
  RESULTS
  Eight cases were injected under surface anesthesia with indirect laryngoscopy at the clinic service. Thirty-eight cases were injected under general anesthesias with micro-laryngoscopes. After six months following up, the voice hoarseness was obviously improved, the congestion or oedema of vocal cord was lessened, and the voice quality was improved as well. The results of F0, jitter, shimmer, NNE acoustics' parameters after treatment 6 months showed: 8 of 48 cases (17.39%) had treatment effect, 22 out of 48 cases (47.83%) had obviously effect, 10 out of 48 cases (21.74%) had cured. The total effectiveness had reached 86.96% (40 of 48 cases). Six of 48 cases (13.04%) was failure.
  
  
  CONCLUSIONS
  Vocal cord injection of Betamethasone for the hoarseness of chronic hypertrophic laryngitis is an effective treatment method.
authors.affiliation: Department of Otorhinolaryngology, Shanghai First People's Hospital Divided, Shanghai 200081, China. nizhsh@public2.sta.net.cn
authors.forename: Guan-Sen
authors.initials: GS
authors.lastname: Ni
authors.forename: Yi
authors.initials: Y
authors.lastname: Qiao
authors.forename: Wen-Wen
authors.initials: WW
authors.lastname: Chen
mesh_terms: D000328:Adult; D001623:Betamethasone / Q000008:administration & dosage / Q000627:therapeutic use*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D007827:Laryngitis / Q000628:therapy*; D008297:Male; D016896:Treatment Outcome; D014827:Vocal Cords; D014833:Voice Quality
chemical_list: D001623:Betamethasone