[Treatment of cutaneous metastases of a squamous cell carcinoma of the leg with topical miltefosine].
BACKGROUND
Miltefosine (Hexadecylphosphocholine) is a chemotherapy, which when applied locally, has demonstrated efficacy in the treatment of cutaneous metastases of breast cancer.


METHODS
A 79 year-old woman developed recurrent in transit cutaneous metastases of a squamous cell carcinoma on her left leg. All lesions completely resolved after topical applications of miltefosine. Tolerance was excellent and the patient remained disease-free 24 months after the end of the treatment.


CONCLUSIONS
Miltefosine, which might prove to be a simple and effective alternative for the usually heavy treatments proposed, warrants further assessment in this context.
Mahieu-Renard
L
L
Service de Dermatologie, Hôpital Sainte-Marguerite, Marseille.
Richard
M-A
MA
Dales
J-P
JP
Buscaylet
S
S
Lagrassa
S
S
Grob
J-J
JJ
D000287:Administration, Topical; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000556:secondary*; D005260:Female; D006801:Humans; D007866:Leg; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy*; D010767:Phosphorylcholine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000556:secondary*
D000970:Antineoplastic Agents; D010767:Phosphorylcholine; C039128:miltefosine