title: Orthopaedic infections: organisms and antibiotic sensitivity.
abstract: Staphylococcus aureus infection remains the commonest organism causing musculoskeletal infection and antibiotic is the mainstay of treatment apart from adequate and appropriate surgical intervention. The exact figure of antibiotic resistance in orthopaedic practice is not known but it is expected to be higher than previously reported as the use of antibiotics is rampant. Its sensitivity to various antibiotics differs from one center to another making local surveillance necessary. From 66 patients with musculoskeletal infections studied in our centre, Staphylococcus aureus was cultured in 50-65% of patients, depending on the sample taken. Fifteen percent of this were methicillin resistant Staphylococcus aureus (MRSA). Staphylococcus aureus was found to be sensitive to cloxacillin in 95% of patients' sample. MRSA remained highly sensitive to vancomycin, clindamycin and fucidic acid.
authors.affiliation: Department of Orthopaedics, School of Medical Sciences, Health Campus, USM, Kelantan, Malaysia.
authors.forename: M I
authors.initials: MI
authors.lastname: Yusof
authors.forename: A H
authors.initials: AH
authors.lastname: Yusof
mesh_terms: D001850:Bone Diseases, Infectious / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D006785:Hospitals, University; D006801:Humans; D008296:Malaysia; D008826:Microbial Sensitivity Tests; D019637:Orthopedic Procedures / Q000009:adverse effects*; D013530:Surgical Wound Infection / Q000382:microbiology*