title: Self-expandable stent-assisted coiling of wide-necked intracranial aneurysms: a single-center experience.
abstract: OBJECTIVE
  Endovascular treatment of wide-necked aneurysms remains a therapeutic challenge. We conducted this study to evaluate the angiographic results and clinical outcome of patients treated with stent-assisted coiling by using a recently available self-expandable intracranial stent.
  
  
  METHODS
  A retrospective review of all patients treated with self-expandable stent-assisted coiling between September 2002 and December 2003 was done. Treatment was attempted in 32 patients with 35 aneurysms. Four of the aneurysms were ruptured. All had either a dome-to-neck ratio less than 2 and/or a neck diameter of 5 mm or larger. Following stent placement, coiling was attempted in 33 of 34 aneurysms. The technical success of the procedure, procedure related complications, and the angiographic results were documented.
  
  
  RESULTS
  In 34 of 35 aneurysms, stent deployment across the neck of the aneurysm was successful. Coiling was performed successfully in 30 of 33 aneurysms. In 20 aneurysms, immediate posttreatment angiography showed either total (17%) or satisfactory (50%) occlusion. Procedure-related mortality occurred in one patient (3.1%). Adverse events occurred in eight patients (25%); in three of them permanent neurologic deficit resulted (9.3%). In six patients, thrombus formation occurred within the stented segments during the procedure and reopro infusion was used. Follow-up angiography was available in 12 (40%) of 30 treated aneurysms.
  
  
  CONCLUSIONS
  In our practice use of the self-expandable stent seemed to facilitate endovascular treatment of wide-necked intracranial aneurysms. Difficulty of deployment and stent thrombogenicity are the main drawbacks of the system.
authors.affiliation: Department of Radiology, Gazi University, Ankara, Turkey.
authors.forename: Sergin
authors.initials: S
authors.lastname: Akpek
authors.forename: Anil
authors.initials: A
authors.lastname: Arat
authors.forename: Hesham
authors.initials: H
authors.lastname: Morsi
authors.forename: Richard P
authors.initials: RP
authors.lastname: Klucznick
authors.forename: Charles M
authors.initials: CM
authors.lastname: Strother
authors.forename: Michel E
authors.initials: ME
authors.lastname: Mawad
mesh_terms: D000328:Adult; D000368:Aged; D002404:Catheterization; D003131:Combined Modality Therapy; D004867:Equipment Design; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents