title: Retention characteristics of a new butylimidazolium-based stationary phase.
abstract: A new HPLC stationary phase has been synthesized based on the ionic liquid n-butylimidazolium bromide. Imidazolium was covalently immobilized on a silica substrate through an n-alkyl tether and the retention characteristics of the resulting stationary phase were evaluated systematically. Using 28 small aromatic test solutes and reversed phase conditions, the linear solvation energy relationship approach was successfully used to characterize this new phase. The retention characteristics of the test solutes show remarkable similarity with phenyl stationary phases, despite the presence of a positive charge on the new imidazolium phase. Operated in the reversed phase mode, this new stationary phase shows considerable promise for the separation of neutral solutes and points to the potential for a truly multi-modal stationary phase.
authors.affiliation: Department of Chemistry, University of Cincinnati, Cincinnati, OH 45221-0172, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Sun
authors.forename: B
authors.initials: B
authors.lastname: Cabovska
authors.forename: C E
authors.initials: CE
authors.lastname: Evans
authors.forename: T H
authors.initials: TH
authors.lastname: Ridgway
authors.forename: A M
authors.initials: AM
authors.lastname: Stalcup
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006841:Hydrocarbons, Aromatic / Q000737:chemistry; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry*; D016014:Linear Models; D012680:Sensitivity and Specificity; D012822:Silicon Dioxide / Q000737:chemistry; D013997:Time Factors
chemical_list: D006841:Hydrocarbons, Aromatic; D007093:Imidazoles; C514468:n-butylimidazolium bromide; D012822:Silicon Dioxide