Sleep spindle detection using artificial neural networks trained with filtered time-domain EEG: a feasibility study.
An artificial neural network (ANN) based on the Multi-Layer Perceptron (MLP) architecture is used for detecting sleep spindles in band-pass filtered electroencephalograms (EEG), without feature extraction. Following optimum classification schemes, the sensitivity of the network ranges from 79.2% to 87.5%, while the false positive rate ranges from 3.8% to 15.5%. Furthermore, due to the operation of the ANN on time-domain EEG data, there is agreement with visual assessment concerning temporal resolution. Specifically, the total inter-spindle interval duration and the total duration of spindles are calculated with 99% and 92% accuracy, respectively. Therefore, the present method may be suitable for investigations of the dynamics among successive inter-spindle intervals, which could provide information on the role of spindles in the sleep process, and for studies of pharmacological effects on sleep structure, as revealed by the modification of total spindle duration.
Ventouras
Errikos M
EM
Department of Medical Instrumentation Technology, Technological Educational Institution of Athens, Ag. Spyridonos Str., Egaleo, Athens 12210, Greece. ericvent@teiath.gr
Monoyiou
Efstratia A
EA
Ktonas
Periklis Y
PY
Paparrigopoulos
Thomas
T
Dikeos
Dimitris G
DG
Uzunoglu
Nikos K
NK
Soldatos
Constantin R
CR
D000513:Alpha Rhythm / Q000145:classification; D001611:Beta Rhythm / Q000145:classification; D004569:Electroencephalography / Q000379:methods*; D005240:Feasibility Studies; D006115:Greece; D006801:Humans; D016571:Neural Networks, Computer; D010363:Pattern Recognition, Automated; D015203:Reproducibility of Results; D012815:Signal Processing, Computer-Assisted; D012894:Sleep Stages; D012895:Sleep, REM / Q000502:physiology*