title: Determinants of health-related quality of life in coronary artery disease patients: a prospective study generating a structural equation model.
abstract: The authors used structural equation modeling to test a conceptual model of HRQL in coronary artery disease. The model, which included biomedical factors and individual and environmental characteristics, was tested in a multicenter group of 465 patients at three timepoints (baseline evaluation of chest pain and 1- and 3-month follow-ups). A satisfactory fit was obtained for the model over time. Depression and anxiety symptoms exerted the most significant influence on HRQL. HRQL and the mediating factors were found to be distinct phenomena. The authors concluded that mediating factors, especially depression and anxiety symptoms, should be taken into consideration in clinical routine if HRQL is regarded as a clinical outcome.
authors.affiliation: Department of Medical Psychology and Psychotherapy, University of Innsbruck, Sonnenburgstr. 9, A-6020 Innsbruck, Austria. stefan.hoefer@uibk.ac.at
authors.forename: Stefan
authors.initials: S
authors.lastname: Höfer
authors.forename: W
authors.initials: W
authors.lastname: Benzer
authors.forename: H
authors.initials: H
authors.lastname: Alber
authors.forename: E
authors.initials: E
authors.lastname: Ruttmann
authors.forename: M
authors.initials: M
authors.lastname: Kopp
authors.forename: G
authors.initials: G
authors.lastname: Schüssler
authors.forename: S
authors.initials: S
authors.lastname: Doering
mesh_terms: D002637:Chest Pain / Q000523:psychology; D003324:Coronary Artery Disease / Q000523:psychology*; D003863:Depression / Q000209:etiology; D004777:Environment; D005260:Female; D005500:Follow-Up Studies; D006304:Health Status; D006801:Humans; D007389:Internal-External Control; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011788:Quality of Life; D012720:Severity of Illness Index; D012944:Social Support; D011795:Surveys and Questionnaires