[Utility of electroconvulsive therapy for severe depression in subjects aged over 65].
The management of depression in subjects aged over 65 is based on the isolated or combined use of antidepressant chemotherapy, psychotherapy and electroconvulsive therapy. Electroconvulsive therapy, under general anaesthesia and use of curare, consists in producing a generalised seizure using a short, pulsed, electrical current administered via the transcranial route. There is renewed interest in electroconvulsive therapy with the development of specific rules and conditions for its use, together with the recruitment of depressed patients resistant to classical treatments in hospital settings. The efficacy of electroconvulsive therapy has been demonstrated in the elderly. The immediate side effects, related to the electrical stimulation and the seizure, such as headaches, nausea, confusion, and transient amnesia, regress within a few minutes or hours after the session. The limits of electroconvulsive therapy are the high risk of relapse on suspension of the sessions, relapse basically related to the severity of the depression. Consolidation electroconvulsive therapy provides new hope for better control of such relapses.
Fossati
P
P
CNRS UMR 7593, Service de psychiatrie adultes du Pr Allilaire, Groupe hospitalier Pitié-Salpétrière, 75013 Paris. philippe.fossati@psl.ap-hop-paris.fr
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000768:Anesthesia, General; D003865:Major Depressive Disorder / Q000628:therapy*; D004565:Electroconvulsive Therapy / Q000009:adverse effects; D006801:Humans; D012008:Recurrence; D012307:Risk Factors; D012640:Seizures / Q000209:etiology; D012720:Severity of Illness Index