title: [Progress on painful diabetic peripheral neuropathy treated by integrative medicine].
abstract: The article reviewed clinical studies on painful diabetic peripheral neuropathy (PDPN) treated by integrative medicine. PDPN, a common complication of diabetes mellitus, which could severely influence patients' quality of life. The keystone and difficulty of PDPN treatment is to relieve pain. Tricyclic anti-depressants are the firstline agents for neuropathic pain but with obvious adverse reactions. Antiepileptic drugs and capsicin can relieve PDPN with less adverse reactions. In recent years, lots of report of clinical studies on DPN treated by TCM or integrative medicine were issued, but those pertinent to PDPN were seldom. Only the papers with independent statistical analysis on effect of pain relieving were selected to review in this article, and the authors presumed that it is feasible to treat PDPN with integrative medicine.
authors.affiliation: Department of Endocrinopathy, Longhua Hospital, Shanghai University of TCM, Shanghai. hunghb0820@yahoo.com.cn
authors.forename: Hong-Bin
authors.initials: HB
authors.lastname: Hong
authors.forename: Rong-Juan
authors.initials: RJ
authors.lastname: Xu
mesh_terms: D000588:Amines / Q000627:therapeutic use; D000639:Amitriptyline / Q000627:therapeutic use; D000700:Analgesics / Q000627:therapeutic use*; D000818:Animals; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D001786:Blood Glucose / Q000378:metabolism; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use; D003929:Diabetic Neuropathies / Q000150:complications / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D000077206:Gabapentin; D006801:Humans; D000077213:Lamotrigine; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D010147:Pain Measurement; D008517:Phytotherapy; D014227:Triazines / Q000627:therapeutic use; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use
chemical_list: D000588:Amines; D000700:Analgesics; D000929:Antidepressive Agents, Tricyclic; D001786:Blood Glucose; D003509:Cyclohexanecarboxylic Acids; D004365:Drugs, Chinese Herbal; D014227:Triazines; D000639:Amitriptyline; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin; D000077213:Lamotrigine