title: Angiotrophic intravascular lymphosarcoma presenting as bi-cavity effusion in a dog.
abstract: A 9-year-old German Shepherd cross was presented with a history of dyspnoea, decreased activity, episodic collapse and abdominal distention. Cytological examination of thoracic and abdominal fluid demonstrated neoplastic cells, either round or mesenchymal in nature. The dog was found to have a mass in the heart-base region. Exploratory thoracotomy was performed to identify the exact nature of the mass histologically, and to determine if it was the source of neoplastic cells seen in the effusions. Histological diagnosis of the mass was mesothelioma. Postoperatively the dog developed thrombocytopenia, probably immune-mediated, which was treated with prednisone therapy. The dog developed signs of respiratory distress shortly before discharge and, due to its deteriorating condition, was euthanased. A necropsy was performed and tissues were collected for histological examination. The histological diagnosis was angiotropic intravascular lymphosarcoma. Diagnosis of mesothelioma was not confirmed.
authors.affiliation: Washington State University, Department of Veterinary Clinical Sciences, PO Box 647060, Pullman, Washington 99164-7060, USA.
authors.forename: L
authors.initials: L
authors.lastname: Ridge
authors.forename: G
authors.initials: G
authors.lastname: Swinney
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D007150:Immunohistochemistry / Q000662:veterinary; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D013908:Thoracotomy / Q000662:veterinary; D019043:Vascular Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*