title: Current status of prosthetic bypass grafts: a review.
abstract: Polymers such as Dacron and polytetrafluoroethylene (PTFE) have been used in high flow states with relative success but with limited application at lower flow states. Newer polymers with greater compliance, biomimicry, and ability to evolve into hybrid prostheses, suitable as smaller vessels, are now being introduced. In view of the advances in tissue engineering, this makes possible the creation of an ideal off-the-shelf bypass graft. We present a broad overview of the current state of prosthetic bypass grafts.
authors.affiliation: Biomaterials & Tissue Engineering Centre, University Department of Surgery, Royal Free and University College Medical School, University College London, UK.
authors.forename: Ruben Y
authors.initials: RY
authors.lastname: Kannan
authors.forename: Henryk J
authors.initials: HJ
authors.lastname: Salacinski
authors.forename: Peter E
authors.initials: PE
authors.lastname: Butler
authors.forename: George
authors.initials: G
authors.lastname: Hamilton
authors.forename: Alexander M
authors.initials: AM
authors.lastname: Seifalian
mesh_terms: D000818:Animals; D001166:Arteriovenous Shunt, Surgical; D001672:Biocompatible Materials / Q000737:chemistry*; D001807:Blood Vessel Prosthesis; D005720:Gamma Rays; D006083:Graft Occlusion, Vascular; D006801:Humans; D008833:Microcirculation; D011108:Polymers / Q000737:chemistry; D011126:Polypropylenes / Q000737:chemistry; D011138:Polytetrafluoroethylene / Q000737:chemistry*; D011140:Polyurethanes / Q000737:chemistry; D006435:Renal Dialysis
chemical_list: D001672:Biocompatible Materials; D011108:Polymers; D011126:Polypropylenes; D011140:Polyurethanes; D011138:Polytetrafluoroethylene