Use of viral vectors for vaccine production in plants.
The small size of plant viral genomes, the ease with which they can be manipulated, and the simplicity of the infection process is making the viral vectors an attractive alternative to the transgenic systems for the expression of foreign proteins in plants. One use of these virus expression systems is for vaccine production. There are two basic types of viral system that have been developed for the production of immunogenic peptides and proteins in plants: epitope presentation and polypeptide expression systems. In this review, we discuss advances made in this field.
Cañizares
M Carmen
MC
John Innes Centre, Norwich, UK.
Nicholson
Liz
L
Lomonossoff
George P
GP
D017794:Alfalfa mosaic virus / Q000235:genetics; D000818:Animals; D017798:Comovirus / Q000235:genetics; D005822:Genetic Vectors / Q000235:genetics*; D010942:Plant Viruses / Q000235:genetics*; D030821:Plants, Genetically Modified / Q000235:genetics / Q000378:metabolism*; D017801:Plum Pox Virus / Q000235:genetics; D017863:Potexvirus / Q000235:genetics; D014027:Tobacco Mosaic Virus / Q000235:genetics; D017864:Tombusvirus / Q000235:genetics; D014614:Vaccines, Synthetic / Q000096:biosynthesis* / Q000235:genetics / Q000276:immunology
D014614:Vaccines, Synthetic