title: Dual linear ion trap/orthogonal acceleration time-of-flight mass spectrometer with improved precursor ion selectivity.
abstract: A new hybrid mass spectrometer based on dual linear ion traps (LITs) and an orthogonal acceleration time-of-flight mass spectrometer (oaTOF), that can achieve MS(n) analysis and high-mass-accuracy detection with high sensitivity, has been developed. Dual-LIT was necessary because, in a single LIT plus oaTOF combination, the LIT pressure favorable for high precursor selectivity in MS(n) analysis (less than 1 mTorr) was far different from an optimum damping pressure (50-100 mTorr) for efficient connection to the TOF mass spectrometer. A dual-LIT solved this problem of inconsistency of the optimum pressures by using the first LIT for MS(n) analysis and the second LIT for collisional damping. This dual-LIT/TOF instrument achieved high-sensitivity MS(n) analysis with high precursor-ion selectivity.
authors.affiliation: Central Research Laboratory, Hitachi, Ltd., Kokubunji-shi, Tokyo, Japan. h-yuichi@crl.hitachi.co.jp
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: Hideki
authors.initials: H
authors.lastname: Hasegawa
authors.forename: Izumi
authors.initials: I
authors.lastname: Waki