title: Analgesic and anti-inflammatory activity of Leonurus sibiricus.
abstract: The methanolic extract of Leonurus sibiricus aerial parts injected intraperitoneally at dose of 250 and 500 mg/kg showed a significant analgesic effect in acetic acid-induced writhing in mice. Moreover, when given orally to rats at dose of 200 and 400 mg/kg, it showed a significant anti-inflammatory activity against carrageenin induced rat paw edema in rats.
authors.affiliation: Pharmacy Discipline, Khulna University, Khulna-9208, Bangladesh.
authors.forename: M Amirul
authors.initials: MA
authors.lastname: Islam
authors.forename: Firoj
authors.initials: F
authors.lastname: Ahmed
authors.forename: A K
authors.initials: AK
authors.lastname: Das
authors.forename: S C
authors.initials: SC
authors.lastname: Bachar
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D004487:Edema / Q000188:drug therapy; D005260:Female; D031332:Leonurus / Q000737:chemistry*; D008297:Male; D051379:Mice; D010146:Pain / Q000188:drug therapy; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D010936:Plant Extracts