Studies on the in vivo hypoglycemic activities of two medicinal plants used in the treatment of diabetes in Jordanian traditional medicine following intranasal administration.
The claimed hypoglycemic activities of Paronychia argentea Lam. (Caryophyllaceae) and Teucrium polium L. (Labiatae), two traditionally widely used medicinal plants in Jordan were evaluated using normoglycemic and alloxan induced hyperglycemic rabbits by intranasal administration of the plant crude extracts (10%) in a vehicle containing 5% (w/w) Pluronic F127. No significant difference was observed between the extract treated and non-treated control animals receiving only water.
Afifi
F U
FU
Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Amman, Jordan. fatueafi@ju.edu.jo
Al-Khalidi
B
B
Khalil
E
E
D000281:Administration, Intranasal; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D029748:Caryophyllaceae / Q000737:chemistry*; D003920:Diabetes Mellitus / Q000188:drug therapy*; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy; D005260:Female; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D007597:Jordan; D008297:Male; D008519:Medicine, Traditional; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000627:therapeutic use; D011817:Rabbits; D031367:Teucrium / Q000737:chemistry*
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts