Radiation-induced cavernomas of the brain.
The purpose of this report is to add support to the growing literature that there is a correlation between radiation and cavernomas of the brain, particularly if the radiation is received in childhood, as well as to increase awareness of this correlation in the radiology community. Retrospective review of our experience returned five patients who received radiation therapy while they were children and developed cavernomas in the irradiated tissues 3-41 years later. Cavernomas should be considered in the differential diagnosis of a hemorrhagic lesion in any patient who has received previous CNS radiation, particularly if he or she underwent radiation therapy in childhood.
Jain
Rajan
R
Department of Radiology, University of Michigan Medical School, Ann Arbor, MI 48202, USA.
Robertson
Patricia L
PL
Gandhi
Dheeraj
D
Gujar
Sachin K
SK
Muraszko
Karin M
KM
Gebarski
Stephen
S
D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000209:etiology*; D002648:Child; D006392:Hemangioma, Cavernous / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D012189:Retrospective Studies; D013997:Time Factors