title: The pectoralis myofascial flap in pharyngolaryngeal surgery after radiotherapy.
abstract: Pharyngocutaneous fistula after total laryngectomy remains a hardly inevitable complication. The predisposing factors are not clearly identified, but prior radiotherapy seems to increase the risk of fistulae. The purpose of this retrospective study was to determine the value of the pectoralis myofascial flap in pharyngeal reconstruction in post-radiotherapy total laryngectomy in order to decrease the risk of fistula formation. The charts of 60 consecutive patients who had undergone total laryngectomy or pharyngolaryngectomy after radiotherapy were analyzed. Twenty-one variables were recorded for each patient. The overall rate of fistula formation was 38% (23% when a pectoralis myofascial flap was used to cover the pharynx and 50% when no flap was used, P = 0.06). The flap-related complications were exceptional. In the subgroup of patients with diabetes mellitus, a history of vascular disease or a poor nutritional status, the use of a flap reduced the fistula formation from 73 to 13% (P = 0.018). The pectoralis myofascial flap covering the pharyngeal sutures in postradiotherapy laryngectomy is particularly useful in a selected group of patients (with diabetes mellitus, history of vascular disease or poor nutritional status).
authors.affiliation: Department of Otorhinolaryngology and Head and Neck Surgery, CHU de Grenoble, BP 217-38043, Grenoble Cedex 9, France. CRighini@chu-grenoble.fr
authors.forename: C
authors.initials: C
authors.lastname: Righini
authors.forename: T
authors.initials: T
authors.lastname: Lequeux
authors.forename: O
authors.initials: O
authors.lastname: Cuisnier
authors.forename: N
authors.initials: N
authors.lastname: Morel
authors.forename: E
authors.initials: E
authors.lastname: Reyt
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D017577:Cutaneous Fistula / Q000150:complications / Q000209:etiology / Q000601:surgery*; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D015994:Incidence; D007825:Laryngectomy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009748:Nutrition Disorders / Q000150:complications; D010369:Pectoralis Muscles / Q000637:transplantation*; D010608:Pharyngeal Diseases / Q000150:complications / Q000209:etiology / Q000601:surgery*; D010611:Pharyngectomy / Q000009:adverse effects; D010614:Pharynx / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D013524:Surgical Flaps; D016896:Treatment Outcome; D014652:Vascular Diseases / Q000150:complications