Temporal data mining for the quality assessment of hemodialysis services.
OBJECTIVE
This paper describes the temporal data mining aspects of a research project that deals with the definition of methods and tools for the assessment of the clinical performance of hemodialysis (HD) services, on the basis of the time series automatically collected during hemodialysis sessions.


METHODS
Intelligent data analysis and temporal data mining techniques are applied to gain insight and to discover knowledge on the causes of unsatisfactory clinical results. In particular, two new methods for association rule discovery and temporal rule discovery are applied to the time series. Such methods exploit several pre-processing techniques, comprising data reduction, multi-scale filtering and temporal abstractions.


RESULTS
We have analyzed the data of more than 5800 dialysis sessions coming from 43 different patients monitored for 19 months. The qualitative rules associating the outcome parameters and the measured variables were examined by the domain experts, which were able to distinguish between rules confirming available background knowledge and unexpected but plausible rules.


CONCLUSIONS
The new methods proposed in the paper are suitable tools for knowledge discovery in clinical time series. Their use in the context of an auditing system for dialysis management helped clinicians to improve their understanding of the patients' behavior.
Bellazzi
Riccardo
R
Dipartimento di Informatica e Sistemistica, Università di Pavia, via Ferrata 1, 27100 Pavia, Italy. riccardo.bellazzi@unipv.it
Larizza
Cristiana
C
Magni
Paolo
P
Bellazzi
Roberto
R
D000465:Algorithms; D001185:Artificial Intelligence; D003628:Database Management Systems; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D011785:Quality Assurance, Health Care; D006435:Renal Dialysis / Q000592:standards*