Automated frequency analysis of synchronous and diffuse sleep spindles.
BACKGROUND
Sleep spindles have different properties in different localizations in the cortex.


OBJECTIVE
First main objective was to develop an amplitude-independent multi-channel spindle detection method. Secondly the method was applied to study the anteroposterior frequency differences of pure synchronous (visible bilaterally, either frontopolarly or centrally) and diffuse (visible bilaterally both frontopolarly and centrally) sleep spindles.


METHODS
A previously presented spindle detector based on the fuzzy reasoning principle and a level detector were combined to form a multi-channel spindle detector.


RESULTS
The spindle detector had a 76.17% true positive rate and 0.93% false-positive rate. Pure central spindles were faster and pure frontal spindles were slower than diffuse spindles measured simultaneously from both locations.


CONCLUSIONS
The study of frequency relations of spindles might give new information about thalamocortical sleep spindle generating mechanisms.
Huupponen
Eero
E
Signal Processing Laboratory, Tampere University of Technology, Korkeakoulunkatu 1, FIN-33101 Tampere, Finland. eero.huupponen@tut.fi
Saastamoinen
Antti
A
Niemi
Jukka
J
Virkkala
Jussi
J
Hasan
Joel
J
Värri
Alpo
A
Himanen
Sari-Leena
SL
D000328:Adult; D002540:Cerebral Cortex / Q000502:physiology*; D003344:Cortical Synchronization / Q000379:methods*; D001330:Electronic Data Processing / Q000379:methods*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D017143:Fuzzy Logic; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography / Q000379:methods; D012372:ROC Curve; D012894:Sleep Stages / Q000502:physiology*; D013997:Time Factors