title: A novel strategy for the asymmetric synthesis of chiral cyclopropane carboxaldehydes.
abstract: A new way of combining chiral auxiliaries and substrate-directable reactions for asymmetric synthesis is described that employs a three-step sequence of aldol-cyclopropanation-retro-aldol reactions for the stereoselective synthesis of enantiopure cyclopropane carboxaldehydes.
authors.affiliation: Department of Chemistry, University of Bath, Bath, UK.
authors.forename: Matt
authors.initials: M
authors.lastname: Cheeseman
authors.forename: Fred J P
authors.initials: FJ
authors.lastname: Feuillet
authors.forename: Andrew L
authors.initials: AL
authors.lastname: Johnson
authors.forename: Steven D
authors.initials: SD
authors.lastname: Bull
mesh_terms: D000447:Aldehydes / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D003521:Cyclopropanes / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D003521:Cyclopropanes; C030797:cyclopropane