title: [Specific clinical, epidemiological patterns and laboratory diagnostics of enterovirus infection in the Republic of Belarus].
abstract: The clinical and epidemiological patterns as well as the results of the laboratory verification of the outbreak of enterovirus infection (EVI) in Minsk during the period of summer-autumn, 2000, are presented. During this outbreak a variety of clinical forms were observed, the serous meningitis being prevalent (57.5%). Practically simultaneous occurrence of infection on the territory of all administrative districts of the city, the predominant involvement of children aged up to 14 years into the outbreak, a high proportion of simultaneous casualities in the multiple foci. A number of circulating enteroviruses (EV)--ECHO 30, ECHO 6 of three serotypes and Coxsackie B5--were simultaneously isolated from clinical material. EV of the same serotypes were isolated from tap drinking water, and neutralizing antibodies to these serotypes were often detected in the patients blood sera. Infectious EV were also present in samples of bottled water and in water reservoirs used for bathing. The routes of EV transmission and the improvement of EVI control are discussed.
authors.forename: T V
authors.initials: TV
authors.lastname: Amvros'eva
authors.forename: N V
authors.initials: NV
authors.lastname: Poklonskaia
authors.forename: Z F
authors.initials: ZF
authors.lastname: Bogush
authors.forename: O N
authors.initials: ON
authors.lastname: Kazinets
authors.forename: F A
authors.initials: FA
authors.lastname: Germanovich
authors.forename: E G
authors.initials: EG
authors.lastname: Fisenko
authors.forename: L P
authors.initials: LP
authors.lastname: Titov
authors.forename: Z B
authors.initials: ZB
authors.lastname: Kvacheva
authors.forename: A A
authors.initials: AA
authors.lastname: Bezruchko
authors.forename: E P
authors.initials: EP
authors.lastname: Scheslenok
mesh_terms: D000293:Adolescent; D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D029822:Enterovirus B, Human / Q000145:classification / Q000276:immunology / Q000302:isolation & purification*; D004769:Enterovirus Infections / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D008582:Meningitis, Aseptic / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D009500:Neutralization Tests; D015995:Prevalence; D002094:Republic of Belarus / Q000453:epidemiology; D012621:Seasons; D012703:Serotyping; D013045:Species Specificity; D013550:Swimming; D014505:Urban Population; D014871:Water Microbiology; D014881:Water Supply
chemical_list: D000914:Antibodies, Viral