title: Quantitative evaluation of coronary arterial stenosis using 16-slice multidetector-row computed tomography: preliminary evaluation of phantom study.
abstract: OBJECTIVE
  The purpose of this study is to consider the possibility of quantitative evaluation of coronary arterial stenosis by using 16-slice multidetector-row computed tomography (MDCT).
  
  
  METHODS
  Simulated coronary arteries were prepared, which consist of 5-mm-diameter acryl tubes with contrast media (270 HU). Simulated stenoses of known density (-33 HU) were created in each coronary artery (25%, 50%, and 75%). Cardiac pulsating with 0, 50, 65, 85, and 105 beats per minute (bpm) was performed. Multiplanar reformation images for each coronary artery were created. Percent stenosis was calculated using the width middle value of boundary part of the arteries.
  
  
  RESULTS
  The stenoses were depicted in all heart rates. Average percent stenosis +/- standard deviation was 27.4 +/- 3.6%, 45.8 +/- 2.6%, and 69.4 +/- 2.7%, respectively. For each percent stenosis, there was a significant difference (P < 0.05).
  
  
  CONCLUSIONS
  Sixteen-slice MDCT has a potential for noninvasive quantitative evaluation of stenosis in coronary arteries.
authors.affiliation: Cardiovascular Imaging Laboratory in Research Park, Keio University School of Medicine, Tokyo, Japan. yamada@mr.med.keio.ac.jp
authors.forename: Minoru
authors.initials: M
authors.lastname: Yamada
authors.forename: Masahiro
authors.initials: M
authors.lastname: Jinzaki
authors.forename: Sachio
authors.initials: S
authors.lastname: Kuribayashi
authors.forename: Kozo
authors.initials: K
authors.lastname: Sato
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Tanami
authors.forename: Shen
authors.initials: S
authors.lastname: Yun
authors.forename: Kosuke
authors.initials: K
authors.lastname: Sasaki
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Okano
authors.forename: Koichi
authors.initials: K
authors.lastname: Sugisawa
mesh_terms: D023921:Coronary Stenosis / Q000000981:diagnostic imaging*; D019047:Phantoms, Imaging; D014057:Tomography, X-Ray Computed / Q000379:methods