title: Dendrimeric Gd(III) complex of a monophosphinated DOTA analogue: optimizing relaxivity by reducing internal motion.
abstract: A marked increase of relaxivity has been observed upon rigidifying the internal frame of Gd-containing PAMAM dendrimers: the effect has been attained by either protonation of the dendrimer or by forming supramolecular adducts with cationic polyaminoacids.
authors.affiliation: Department of Inorganic Chemistry, Universita Karlova, Hlavova 2030, 128 40, Prague 2, Czech Republic. petrh@natur.cuni.cz
authors.forename: Jakub
authors.initials: J
authors.lastname: Rudovsky
authors.forename: Petr
authors.initials: P
authors.lastname: Hermann
authors.forename: Mauro
authors.initials: M
authors.lastname: Botta
authors.forename: Silvio
authors.initials: S
authors.lastname: Aime
authors.forename: Ivan
authors.initials: I
authors.lastname: Lukes
mesh_terms: D050091:Dendrimers; D005682:Gadolinium / Q000737:chemistry*; D006573:Heterocyclic Compounds, 1-Ring / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D011073:Polyamines / Q000737:chemistry*
chemical_list: D050091:Dendrimers; D006573:Heterocyclic Compounds, 1-Ring; D009942:Organometallic Compounds; C104700:PAMAM Starburst; D011073:Polyamines; C071349:1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid; D005682:Gadolinium