Schwannoma with neuroblastoma-like rosettes: an unusual morphologic variant.
In the past ten years, seven cases of schwannomas with giant fibrillar rosettes or perivascular rosettes have been reported. As these unusual variants of schwannomas had areas with hyperchromatic, small round cells recapitulating the appearance of a neuroblastoma, they received the descriptive name of neuroblastoma-like schwannomas. We herein report two additional cases of this unique variant of schwannoma and provide differential diagnostic considerations.
Lewis
Zachary T
ZT
Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.
Geisinger
Kim R
KR
Pichardo
Rita
R
Sangueza
Omar P
OP
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009442:Neurilemmoma / Q000378:metabolism / Q000473:pathology*; D009447:Neuroblastoma / Q000473:pathology; D009418:S100 Proteins / Q000378:metabolism; D012983:Soft Tissue Neoplasms / Q000378:metabolism / Q000473:pathology*
D009418:S100 Proteins