Deep brain stimulation in a patient on immunosuppressive therapy after renal transplant.
We performed thalamic deep brain stimulation (DBS) surgery to treat severe essential tremor in a 36 year-old woman who had undergone cadaveric renal transplant four years earlier. She was receiving chronic immunosuppressive therapy. Post-operative healing was normal and there have been no infections of the DBS hardware. There were no peri-operative complications and no rejection of the transplanted kidney. She remains on the same systemic immunosuppressive agents as pre-operatively: prednisone, cyclosporine, and mycophenolate mofetil (CellCept). DBS surgery may be safely performed in carefully selected patients on systemic immunosuppression after renal transplant.
Samii
Ali
A
VAPSHCS, Department of Neurology, University of Washington, 1660 S. Columbian Way, mailstop 127, Seattle, WA 98108, USA. asamii@u.washington.edu
Slimp
Jefferson C
JC
Hogan
Patrick J
PJ
Goodkin
Robert
R
D000328:Adult; D046690:Deep Brain Stimulation; D020329:Essential Tremor / Q000628:therapy*; D005260:Female; D006084:Graft Rejection / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016030:Kidney Transplantation; D011183:Postoperative Complications; D013788:Thalamus / Q000502:physiology
D007166:Immunosuppressive Agents