title: Thioredoxin - structural and functional complexity.
abstract: Thioredoxins are small globular proteins that proved to be excellent model for investigating the relationship between the structure of protein and their physico-chemical and functional properties. The results from the experiments on thioredoxins offer the basic for the development of the new paradigms in the field of chemistry, biophysics and biology of proteins, with special attention to redox reaction in living cells, protein stability and design. It is a good example of broad class of sulphur-containing redox proteins.
authors.affiliation: Department of Biochemistry, Faculty of Natural Sciences, Comenius University, Mlynská dolina CH-1, 842 15 Bratislava 4, Slovakia. pstefankova@fns.uniba.sk
authors.forename: P
authors.initials: P
authors.lastname: Stefanková
authors.forename: M
authors.initials: M
authors.lastname: Kollárová
authors.forename: I
authors.initials: I
authors.lastname: Barák
mesh_terms: D000818:Animals; D001665:Binding Sites; D006801:Humans; D008956:Models, Chemical; D008958:Models, Molecular; D010084:Oxidation-Reduction; D011485:Protein Binding; D011487:Protein Conformation; D015398:Signal Transduction / Q000502:physiology*; D013329:Structure-Activity Relationship; D013879:Thioredoxins / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D013879:Thioredoxins