[Clinical observation on triple-therapy for terminating ectopic pregnancy].
OBJECTIVE
To select a safe, quick and effective method for terminating ectopic pregnancy (EP) with few adverse effects.


METHODS
Patients were divided into 2 groups. The observed group was treated with methotrexate (MTX, 50 mg/m2 for single dose intramuscular injection) plus RU 486 (600 mg taken orally in the morning with empty stomach, followed with fasting for 2 hrs) and Waiyun Zhuyu decoction (WZD, one dose a day for 7-10 days). The control group was only treated with MTX, with the same regimen as used in the observed group.


RESULTS
The curative rate, time for blood beta-HCG recovering, lump absorption time, and tube recanalization rate in the observed group were better than those in the control group (P < 0.01). CONCLUSION; The key links for successfully treating EP with conservative drug therpy are to diagnose the disease early and clearly, and to select indicative subject strictly. The scheme of single dose administration of MTX plus RU486 combined with WZD, with its high efficacy and few adverse reaction, may be used as the first choice for referential clinical drugs administration.
Liao
Zhen
Z
Department of Obstetrics and Gynecology, Huazhou Municipal People's Hospital, Guangdong.
Chen
Guang-Song
GS
Ou
Gui-Zhen
GZ
D000020:Abortifacient Agents, Nonsteroidal / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage*; D015735:Mifepristone / Q000008:administration & dosage*; D008517:Phytotherapy; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000188:drug therapy*; D012189:Retrospective Studies; D016896:Treatment Outcome
D000020:Abortifacient Agents, Nonsteroidal; D004365:Drugs, Chinese Herbal; D015735:Mifepristone; D008727:Methotrexate