title: Impact on delirium detection of using a sensitive instrument integrated into clinical practice.
abstract: Early symptoms of delirium often go unnoticed. The Nursing Delirium Screening Scale (Nu-DESC) is a recently developed short, accurate and sensitive 24-h screening instrument. The Nu-DESC is more sensitive than the instrument from which it was derived, the Confusion Rating Scale (CRS). This study examined the impact on delirium detection of using the Nu-DESC over the CRS in 134 consecutive oncology patients. Expected false-negative rate (FNR) reductions at different delirium prevalence rates when using the Nu-DESC compared to the CRS and the number needed to screen (NNS) by the Nu-DESC were calculated. Kaplan-Meier survival analyses were used to study Nu-DESC-CRS divergences in delirium status and length of delirium-free survival. Ninety-nine patients were negative for delirium according to both tests. Of the remaining 35 patients, 16 had identical Nu-DESC-CRS delirium status and delirium-free survival, whereas 19 were detected later by the CRS (mean, 4.8 days). Among the 19 patients, 6 were still CRS negative upon hospital discharge. Integrating a continuous and sensitive delirium assessment instrument into usual care can facilitate its recognition, since more cases of delirium are diagnosed and patients are detected earlier.
authors.affiliation: Centre de Recherche en Cancérologie de L'Hôtel-Dieu de Québec, Quebec City, Canada G1R 2J6. jean-david.gaudreau.1@ulaval.ca
authors.forename: Jean-David
authors.initials: JD
authors.lastname: Gaudreau
authors.forename: Pierre
authors.initials: P
authors.lastname: Gagnon
authors.forename: François
authors.initials: F
authors.lastname: Harel
authors.forename: Marc-André
authors.initials: MA
authors.lastname: Roy
mesh_terms: D000328:Adult; D003693:Delirium / Q000175:diagnosis*; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000295:instrumentation*; D008495:Medical Oncology; D008875:Middle Aged; D011792:Quebec; D012680:Sensitivity and Specificity