title: [Dental care of patients with leukemia].
abstract: Leukemias include a variety of acute and chronic malignant hematological diseases that require antineoplastic chemotherapy. Hematological stem cell transplantation allows an aggressive chemotherapy during which patients suffer from severe immunosuppression. Oral infections may cause serious complications during this immunosuppression. Therefore, professional diagnosis and elimination of oral infection foci must be carried out as early as possible before such treatment. Aggressive chemotherapy causes hyposalivation and as a consequence an increased risk for oral hard and soft tissue diseases. Adequate oral care before, during and after chemotherapy combined with a stem cell transplantation is necessary to prevent oral diseases and systemic complications of oral origin.
authors.affiliation: Institut für Präventivzahnmedizin und Orale Mikrobiologie, Universitätskliniken für Zahnmedizin, Universität Basel.
authors.forename: Tuomas
authors.initials: T
authors.lastname: Waltimo
authors.forename: Susanne
authors.initials: S
authors.lastname: Christen
authors.forename: Jukka H
authors.initials: JH
authors.lastname: Meurman
authors.forename: Andreas
authors.initials: A
authors.lastname: Filippi
mesh_terms: D000208:Acute Disease; D000970:Antineoplastic Agents / Q000009:adverse effects; D002180:Candidiasis, Oral / Q000209:etiology; D002908:Chronic Disease; D017742:Dental Care for Chronically Ill / Q000379:methods*; D005491:Focal Infection, Dental / Q000209:etiology / Q000517:prevention & control; D006086:Graft vs Host Disease / Q000209:etiology; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007938:Leukemia / Q000145:classification / Q000150:complications* / Q000628:therapy; D009894:Opportunistic Infections / Q000209:etiology; D010510:Periodontal Diseases / Q000209:etiology; D017213:Root Caries / Q000209:etiology; D013280:Stomatitis / Q000209:etiology; D014987:Xerostomia / Q000150:complications / Q000209:etiology
chemical_list: D000970:Antineoplastic Agents; D007166:Immunosuppressive Agents