title: MR imaging of salivary duct carcinoma.
abstract: OBJECTIVE
  Salivary duct carcinoma (SDC) is regarded as a high-grade malignancy in the current classification of salivary gland neoplasms. The aim of our study was to describe the MR imaging features of SDC.
  
  
  METHODS
  Nine patients with SDC underwent MR imaging study. The apparent diffusion coefficient (ADC) values of SDCs were measured from diffusion-weighted images. Time-signal intensity curves (TICs) of the tumors on dynamic MR images were plotted, and washout ratios were also calculated. TICs were divided into four types: type A, curve peaks <120 seconds after administration of contrast material with high washout ratio (> or =30%); type B, curve peaks <120 seconds with low washout ratio (<30%); type C, curve peaks >120 seconds; type D, nonenhanced. We correlated the MR findings of SDC with the pathologic findings.
  
  
  RESULTS
  All tumors had ill-defined margins and showed low to moderately high signal intensity for contralateral parotid gland on T2-weighted images. The average of the ADC values of the SDCs was 1.16 +/- 0.14 [SD] x 10(-3)mm(2)/s. Seven of nine (78%) tumors had type B enhancement. On the other hand, six of nine (67%) tumors with rich fibrotic tissue also had type C enhancement.
  
  
  CONCLUSIONS
  The findings of ill-defined margin, early enhancement with low washout ratio (type B), and low ADC value (1.22 x 10(-3)mm(2)/s) were useful for suggesting malignant salivary gland tumors. Although it was reported that type C enhancement was specific for pleomorphic adenoma, SDC frequently has type C-enhanced focus.
authors.affiliation: Department of Radiology, Chiba University Hospital, Chiba City, Chiba, Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Motoori
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Iida
authors.forename: Yuichirou
authors.initials: Y
authors.lastname: Nagai
authors.forename: Seiji
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Takuya
authors.initials: T
authors.lastname: Ueda
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Funatsu
authors.forename: Hisao
authors.initials: H
authors.lastname: Ito
authors.forename: Okamoto
authors.initials: O
authors.lastname: Yoshitaka
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography