title: Small cell lung cancer associated with systemic sclerosis.
abstract: A 51-year-old woman developed small cell lung cancer (SCLC). She was a non-smoker and had interstitial pneumonia associated with systemic sclerosis (SSc). Sixteen additional cases obtained from the literature describing patients with SCLC associated with SSc are reviewed. The majority of patients were women with underlying interstitial pneumonia. In 3 patients who were non-smokers, interstitial pneumonia was complicated and cancer had developed in the peripheral lung field but not in the central lung field. Since SCLC is very rare in non-smokers, these findings suggest a positive association between SCLC and interstitial pneumonia associated with SSc.
authors.affiliation: First Department of Internal Medicine, faculty of Medicine, Kagawa University, Kagawa.
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Kanaji
authors.forename: Jiro
authors.initials: J
authors.lastname: Fujita
authors.forename: Shuji
authors.initials: S
authors.lastname: Bandoh
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Fukumoto
authors.forename: Masashi
authors.initials: M
authors.lastname: Ishikawa
authors.forename: Reiji
authors.initials: R
authors.lastname: Haba
authors.forename: Tomoya
authors.initials: T
authors.lastname: Ishii
authors.forename: Akihito
authors.initials: A
authors.lastname: Kubo
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Ishida
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D018288:Carcinoma, Small Cell / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008875:Middle Aged; D013902:Radiography, Thoracic; D012595:Scleroderma, Systemic / Q000150:complications*; D014057:Tomography, X-Ray Computed