title: Calcifying odontogenic cyst associated with complex odontoma: case report and review of the literature.
abstract: We report a calcifying odontogenic cyst associated with odontoma (COCaO) and an included permanent canine in the superior maxilla, in a 19 year-old-man. The calcifying odontogenic cyst (COC) was first described as a distinct entity by Gorlin et al in 1962. The lesion is a mixed odontogenic benign tumor, and although most of the cases present cystic characteristics, a few are of the solid type (15%), and its rare malignant transformation is well documented. The COC may occur in association with other odontogenic tumors, the most common is the odontoma, occurring in about 24% of the cases. For this association the term Odontocalcifying odontogenic cyst has been suggested. Radiographically is a well defined mixed lesion and histologically consists of a large cyst. In the central area of the cyst enamel and dentin deposits can be found, irregularly distributed in areas and in other parts it takes on a well defined organoid aspect. A thorough review of literature takes place and the pathogenesis is discussed.
authors.affiliation: Servicio de Cirugía Maxilofacial, Hospital Universitario Virgen Macarena, Sevilla. sgallana@hotmail.com
authors.forename: Silvia
authors.initials: S
authors.lastname: Gallana-Alvarez
authors.forename: Francisco
authors.initials: F
authors.lastname: Mayorga-Jimenez
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Torres-Gómez
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Avellá-Vecino
authors.forename: Clara
authors.initials: C
authors.lastname: Salazar-Fernandez
mesh_terms: D002648:Child; D003481:Cuspid / Q000473:pathology; D006801:Humans; D008297:Male; D008441:Maxillary Neoplasms / Q000150:complications* / Q000473:pathology; D018333:Odontogenic Cyst, Calcifying / Q000150:complications* / Q000473:pathology; D009810:Odontoma / Q000150:complications* / Q000473:pathology; D014095:Tooth, Impacted / Q000150:complications / Q000473:pathology