One pot synthesis of 3,5-alkylated acetophenone and methyl benzoate derivatives via an anionic domino process.
The reaction of primary 1,3-dinitroalkanes with 2-ene-1,4-dione or 2-ene-4-oxo ester derivatives in acetonitrile with DBU as base, allow the one pot synthesis of 3,5-alkylated acetophenones and methyl benzoate derivatives respectively via an anionic domino process.
Ballini
Roberto
R
Dipartimento di Scienze Chimiche dell'Università, Via S. Agostino 1, 62032, Camerino, Italy. roberto.ballini@unicam.it
Barboni
Luciano
L
Fiorini
Dennis
D
Giarlo
Guido
G
Palmieri
Alessandro
A
D000098:Acetophenones / Q000138:chemical synthesis*; D000838:Anions / Q000737:chemistry; D001565:Benzoates / Q000138:chemical synthesis*; D015394:Molecular Structure
D000098:Acetophenones; D000838:Anions; D001565:Benzoates; C044605:methyl benzoate