[Results of an open prospective controlled randomized comparative trial of flurbiprofen and paracetamol efficacy and tolerance in patients with throat pain].
OBJECTIVE
To compare efficacy and safety of strepfen (flurbiprofen) to those of oral paracetamol in acute infections of the upper respiratory tracts for relief of throat pain (TP).


METHODS
Of 60 patients 30 ones took strepfen, 30 controls took paracetamol. The intensity and dynamics of throat pain and pharyngeal discomfort were assessed by 10-point subjective visual-analog scale.


RESULTS
Strepfen is similar by an analgetic effect to paracetamol. Strepfen acts rapidly (in 5-15 min) and its analgetic effect lasts about 3 hours. Paracetamol begins to relieve pain 30-45 min after its intake. The drug is well tolerated, serious side effects are absent.


CONCLUSIONS
Strepfen can be recommended for relief of throat pains and pharyngeal paresthesia in patients with acute and chronic pharyngeal pathology.
Sedinkin
A A
AA
Balandin
A V
AV
Dimova
A D
AD
D000082:Acetaminophen / Q000627:therapeutic use*; D000293:Adolescent; D000328:Adult; D000368:Aged; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use*; D005260:Female; D005480:Flurbiprofen / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy; D010612:Pharyngitis / Q000188:drug therapy*
D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen; D005480:Flurbiprofen