Encapsulating peritonitis and familial Mediterranean fever.
OBJECTIVE
To investigate the relationship between encapsulating peritonitis and familial Mediterranean fever (FMF).


METHODS
The patient had a history of type 2 diabetes and laparoscopic cholecystectomy was performed one year ago for cholelithiasis. Eleven months after the operation she developed massive ascites. Biochemical evaluation revealed hyperglycemia, mild Fe deficiency anemia, hypoalbuminemia and a CA-125 level of 2 700 IU. Ascitic evaluation showed characteristics of exudation with a cell count of 580/mm(3). Abdominal CT showed omental thickening and massive ascites. At exploratory laparotomy there was generalized thickening of the peritoneum and a laparoscopic clip encapsulated by fibrous tissue was found adherent to the uterus. Biopsies were negative for malignancy and a prophylactic total abdominal hysterectomy and bilateral salpingooophorectomy were performed.


RESULTS
The histopathological evaluation was compatible with chronic nonspecific findings and mild mesothelial proliferation and chronic inflammation at the uterine serosa and liver biopsy showed inactive cirrhosis.


CONCLUSIONS
The patient was evaluated as sclerosing encapsulating peritonitis induced by the laparoscopic clip acting as a foreign body. Due to the fact that the patient had FMF the immune response was probably exaggerated.
Dabak
Resat
R
Department of Family Medicine, Kartal State Hospital, 36660 Istanbul, Turkey.
Uygur-Bayramiçli
Oya
O
Aydin
Didem-Kiliç
DK
Dolapçioglu
Can
C
Gemici
Cengiz
C
Erginel
Turgay
T
Turan
Cem
C
Karadayi
Nimet
N
D000368:Aged; D002769:Cholelithiasis / Q000601:surgery; D010505:Familial Mediterranean Fever / Q000150:complications*; D005260:Female; D005547:Foreign Bodies / Q000150:complications*; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects*; D010538:Peritonitis / Q000209:etiology*; D013525:Surgical Instruments / Q000009:adverse effects*