title: Effects of shenmai injection on blood SOD activity and MDA level in senile patients with coronary heart disease.
abstract: In order to approach the effects of Shenmai Injection on SOD activity and MDA level in the senile patients with coronary heart disease, 48 cases, who had stenosis of over 70% in more than one branches of the coronary arteries, were assigned randomly into a treatment group (given Shenmai Injection plus the routine treatment) and a control group (given the routine treatment only). The superoxide dismutase (SOD) activity and malondialdehyde (MDA) level were determined before treatment and at the end of a 3-week treatment. The results showed that in the treatment group, the SOD activity was significantly increased (P<0.05) and the MDA level markedly decreased (P<0.01) in the treatment group. It can be concluded that Shenmai Injection may enhancethe antioxidant ability of the senile patients with coronary heart disease.
authors.affiliation: Geriatric and Cardiovascular Department, First Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Xianming
authors.initials: X
authors.lastname: Su
authors.forename: Yi
authors.initials: Y
authors.lastname: Ma
authors.forename: Ruowen
authors.initials: R
authors.lastname: Huang
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Wang
authors.forename: Yongxing
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy / Q000201:enzymology; D003327:Coronary Disease / Q000188:drug therapy* / Q000201:enzymology; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use*; D013482:Superoxide Dismutase / Q000097:blood*
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D010936:Plant Extracts; C009252:fructus schizandrae, radix ginseng, radix ophiopogonis drug combination; D008315:Malondialdehyde; D013482:Superoxide Dismutase