Quantification of manual force control and tremor.
Isometric impulse frequencies associated with active tremor and force regulation were examined in 10 patients with idiopathic Parkinson's disease (PD) and in 10 older adults (OAs) who performed an isometric tracing task. The authors decoupled and analyzed the data to determine whether PD-related tremor in the thumb and in the index finger during isometric force control are related and whether PD impairs the performance of volitional force control beyond the errors contributed by tremor. After decoupling, there were clear and robust differences in PD patients' control of isometric force that could not be attributed to action-tremor error. Those errors, which occurred in the absence of movement, suggest impairment in coordinated recruitment and derecruitment of motor units during a fine-motor task.
Spirduso
W W
WW
Department of Kinesiology and Health Education, The University of Texas at Austin, Austin, TX 78712, USA. spirduso@mail.utexas.edu
Francis
K
K
Eakin
T
T
Stanford
C
C
D000328:Adult; D000368:Aged; D015444:Exercise; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D018737:Hand Strength / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000503:physiopathology; D011597:Psychomotor Performance / Q000502:physiology; D012720:Severity of Illness Index; D013028:Space Perception; D014202:Tremor / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D014796:Visual Perception