title: Hypereosinophilic syndrome: two case reports of contrasting variants.
abstract: Two cases of hypereosinophilic syndrome that illustrate different variants are reported. Recognition of the specific variant is important because the treatments differ. Patients with hypereosinophilic syndrome should be monitored for evidence of a myeloproliferative process because treatment with tyrosine kinase inhibitors in these patients is effective and may prevent significant morbidity.
authors.affiliation: Department of Pathology, Texas A & M Health Science Center, College of Medicine, Scott and White Hospital, Temple, TX 76508, USA. jszymanski@swmail.sw.org
authors.forename: Jared
authors.initials: J
authors.lastname: Szymanski
authors.forename: Edward
authors.initials: E
authors.lastname: Rappaport
mesh_terms: D000328:Adult; D001549:Benzamides; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D000068877:Imatinib Mesylate; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000627:therapeutic use; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use
chemical_list: D001549:Benzamides; D010879:Piperazines; D047428:Protein Kinase Inhibitors; D011743:Pyrimidines; D000068877:Imatinib Mesylate