Activity of medicinal plant extracts against hospital isolates of methicillin-resistant Staphylococcus aureus.
Aqueous and ethanolic extracts of ten traditional Thai medicinal plants were investigated for their ability to inhibit 35 hospital isolates of methicillin-resistant Staphylococcus aureus (MRSA). Nine medicinal plants displayed activity against all isolates tested. Ethanolic extracts of Garcinia mangostana, Punica granatum and Quercus infectoria were most effective, with MICs for MRSA isolates of 0.05-0.4, 0.2-0.4 and 0.2-0.4 mg/mL, respectively, and for S. aureus ATCC 25923 of 0.1, 0.2 and 0.1 mg/mL, respectively. MBCs for MRSA isolates were 0.1-0.4, 1.6-3.2 and 0.4-1.6 mg/mL, and for S. aureus ATCC 25923 were 0.4, 3.2 and 1.6 mg/mL, respectively.
Voravuthikunchai
S P
SP
Department of Microbiology, Faculty of Science, Prince of Songkla University, Hatyai, Songkla, Thailand. supayang.v@psu.ac.th
Kitpipit
L
L
D000431:Ethanol; D029762:Garcinia mangostana; D006801:Humans; D029561:Lythraceae; D016106:Methicillin Resistance / Q000235:genetics; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D029963:Quercus; D013203:Staphylococcal Infections / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics
D010936:Plant Extracts; D000431:Ethanol