title: Clinical quiz: a pediatric case presenting with fever and diffuse myalgia.
abstract: Familial Mediterranean fever (FMF) is a multisystem disease characterized by recurrent polyserositis episodes seen in certain ethnic groups. In recent years the clinical picture of FMF has been expanded and severe myalgia is a frequently recognized component of the syndrome. Protracted febrile myalgia syndrome (PFMS), characterized by severe paralyzing myalgia, high fever, abdominal pain, diarrhea, arthritis/arthralgia, and transient vasculitic rashes mimicking Henoch-Schonlein purpura, was first described in patients with FMF in 1994. We describe an 11-year-old Turkish girl with a second attack of PFMS before being diagnosed as having FMF, emphasizing the importance of myalgia for the diagnosis of FMF even in the absence of other symptoms.
authors.affiliation: Department of Pediatrics, Dokuz Eylül University Medical Faculty, Inciralti, Izmir, Turkey.
authors.forename: Alper
authors.initials: A
authors.lastname: Soylu
authors.forename: Yeşim
authors.initials: Y
authors.lastname: Oztürk
authors.forename: Belde
authors.initials: B
authors.lastname: Kasap
authors.forename: Nilüfer
authors.initials: N
authors.lastname: Akman
authors.forename: Mehmet
authors.initials: M
authors.lastname: Türkmen
authors.forename: Salih
authors.initials: S
authors.lastname: Kavukçu
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002648:Child; D010505:Familial Mediterranean Fever / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D009135:Muscular Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D010146:Pain / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D011239:Prednisolone / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone