Prenatal diagnostic decision-making in adolescents.
OBJECTIVE
We sought to evaluate the prenatal decision-making of pregnant adolescents identified at increased risk for identifiable fetal genetic abnormalities.


METHODS
A retrospective review of records of gravid women 19 years old or younger undergoing genetic counseling from 2001-2003 (inclusive) was undertaken.


METHODS
Hospital-based academic center.


METHODS
Thirty-seven women were identified; four cases did not meet inclusion criteria.


METHODS
None.


METHODS
Decision to undergo or forgo invasive prenatal testing.


RESULTS
Of the 33 women included in this study, the average age was 17.6 years (range: 15-19). Eighteen were Latinas, eight were African-Americans, and seven were Caucasians. Sixteen women had positive maternal serum screening outcomes; nine women sought counseling because of personal/family histories of genetic abnormalities, seven sought counseling after fetal structural anomalies were detected by ultrasound, and one woman sought counseling because she and her partner were positive for Mendelian disorder screening (sickle cell disease). Sixteen of the women (48.5%) chose to undergo invasive testing (15 amniocenteses, one chorionic villus sampling) whereas 17 (51.5%) chose to forgo invasive testing.


CONCLUSIONS
Adolescents offered invasive prenatal diagnosis will chose to undergo or forgo such testing based on diagnostic and personal criteria as do adult women. Nonetheless, unique adolescent issues may make the process by which information is obtained and communicated during counseling to be different from counseling provided to adults. The development of new genetic screening and diagnostic protocols has and will increase the number of pregnant adolescent women who will be offered genetic counseling during their pregnancies. Such an increase in numbers will place considerably more pressure on an already taxed genetic counseling system; accordingly, new counseling paradigms will need to be developed to provide service to an expanded patient population seeking information for an increasing number of genetic issues.
Plaga
Stacey L
SL
Graduate Program in Genetic Counseling, Northwestern University, Chicago, IL, USA.
Demarco
Kristin
K
Shulman
Lee P
LP
D000293:Adolescent; D000294:Adolescent Behavior; D000328:Adult; D000649:Amniocentesis; D000755:Anemia, Sickle Cell / Q000175:diagnosis; D044383:Black People; D015193:Chorionic Villi Sampling; D003657:Decision Making; D004314:Down Syndrome / Q000175:diagnosis; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis; D005817:Genetic Counseling; D005820:Genetic Testing; D006630:Hispanic or Latino; D006801:Humans; D009436:Neural Tube Defects / Q000175:diagnosis; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012189:Retrospective Studies; D012307:Risk Factors; D016216:Ultrasonography, Prenatal; D044465:White People; D001741:Black or African American