title: Tuning the size of macrocyclic cavities in trianglimine macrocycles.
abstract: The synthesis of aromatic dicarboxaldehydes is described along with their reactivity in the [3 + 3] cyclocondensation reaction with (1R,2R)-diaminocyclohexane to give trianglimine macrocycles. In particular, the scope and limitation of the reaction with regard to complete control of the cavity size of the macrocycles is discussed producing a total of 11 macrocycles with different cavity sizes ranging from 9 to 23 angstroms.
authors.affiliation: Supramolecular and Biomolecular Chemistry Laboratory, Chemistry (C-4), School of Biomedical and Molecular Sciences, The University of Surrey, Guildford, UKGU2 7XH. n.kuhnert@surrey.ac.uk
authors.forename: Nikolai
authors.initials: N
authors.lastname: Kuhnert
authors.forename: Nicolai
authors.initials: N
authors.lastname: Burzlaff
authors.forename: Chirag
authors.initials: C
authors.lastname: Patel
authors.forename: Ana
authors.initials: A
authors.lastname: Lopez-Periago
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared
chemical_list: D000447:Aldehydes