title: Penicillin G acylase catalyzed Markovnikov addition of allopurinol to vinyl ester.
abstract: A new enzymatic process is reported, in which penicillin G acylase from Escherichia coli displays a promiscuous activity in catalyzing the Markovnikov addition of allopurinol to vinyl ester.
authors.affiliation: Department of Chemistry, Zhejiang University, Hangzhou, 310027, People's Republic of China.
authors.forename: Wei-Bo
authors.initials: WB
authors.lastname: Wu
authors.forename: Na
authors.initials: N
authors.lastname: Wang
authors.forename: Jian-Ming
authors.initials: JM
authors.lastname: Xu
authors.forename: Qi
authors.initials: Q
authors.lastname: Wu
authors.forename: Xian-Fu
authors.initials: XF
authors.lastname: Lin
mesh_terms: D000493:Allopurinol / Q000737:chemistry*; D002384:Catalysis; D004926:Escherichia coli / Q000201:enzymology; D004952:Esters / Q000737:chemistry*; D015394:Molecular Structure; D010399:Penicillin Amidase / Q000737:chemistry*; D011687:Purines / Q000138:chemical synthesis*; D013997:Time Factors; D014753:Vinyl Compounds / Q000737:chemistry*
chemical_list: D004952:Esters; D011687:Purines; D014753:Vinyl Compounds; D000493:Allopurinol; D010399:Penicillin Amidase