title: Trisomy 8 as the sole cytogenetic abnormality in a case of extraskeletal mesenchymal chondrosarcoma.
abstract: Mesenchymal chondrosarcoma is a rare malignant tumor that comprises about 3-10% of all sarcomas. Reports of cytogenetic studies of mesenchymal chondrosarcoma are limited and no consistent cytogenetic abnormality has surfaced. Some mesenchymal chondrosarcomas have a t(11;22) translocation suggesting a relationship with the PNET/Ewing tumor family. We report what to our knowledge is the first case of trisomy 8 as the sole cytogenetic abnormality in a mesenchymal chondrosarcoma.
authors.affiliation: Department of Pathology and Cytogenetics, Oregon Health and Sciences University, 3181 S.W. Sam Jackson Park, Dillehunt Hall, L471, Portland, Oregon 97201-3098, USA. gatterk@ohsu.edu
authors.forename: Ken M
authors.initials: KM
authors.lastname: Gatter
authors.forename: Susan
authors.initials: S
authors.lastname: Olson
authors.forename: Helen
authors.initials: H
authors.lastname: Lawce
authors.forename: Anne E
authors.initials: AE
authors.lastname: Rader
mesh_terms: D002648:Child; D018211:Chondrosarcoma, Mesenchymal / Q000235:genetics*; D002898:Chromosomes, Human, Pair 8; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D012983:Soft Tissue Neoplasms / Q000235:genetics* / Q000473:pathology; D013848:Thigh; D014314:Trisomy