title: Neurodistribution of androgen receptor immunoreactivity in the male frog, Rana esculenta.
abstract: Sexual behavior in vertebrates depends on the cyclic release of steroids and their binding to the brain receptors. Previously, we demonstrated the presence of specific binding of (3)H-testosterone and staining with PG-21 in the brain of the adult male frog, Rana esculenta. Here, we report our further receptor characterization using an anti-androgen receptor antiserum, PG-21, and the androgen site of action in frog brain. Nuclei, which contained cells labeled for the androgen receptor (AR), were mainly identified in the olfactory bulbs, preoptic-septal region, infundibulum, amygdala, thalamus, tectum, torus semicircularis, and medulla. The neuroanatomical AR staining appears similar to that in other lower vertebrates.
authors.affiliation: Department of Biological Sciences, Federico II University of Naples, Napoli, Italy. giulia.guerriero@unina.it
authors.forename: G
authors.initials: G
authors.lastname: Guerriero
authors.forename: G S
authors.initials: GS
authors.lastname: Prins
authors.forename: L
authors.initials: L
authors.lastname: Birch
authors.forename: G
authors.initials: G
authors.lastname: Ciarcia
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D001923:Brain Chemistry / Q000502:physiology; D007150:Immunohistochemistry; D008297:Male; D011893:Rana esculenta / Q000378:metabolism*; D011944:Receptors, Androgen / Q000378:metabolism*
chemical_list: D011944:Receptors, Androgen