title: Successful laser ablation of diffuse laryngeal swelling in posttransplant lymphoproliferative disorder: the Japanese first case.
abstract: Posttransplant lymphoproliferative disorder (PTLD) is a well-known complication of pediatric organ transplantation. The first symptoms are often in the ear, nose, or throat (ENT) area. We report the first Japanese case of an airway obstruction in PTLD. A 7-year-old boy who had a liver transplant at the age of 2 years presented with progressive stridor. Fiberoptic examination revealed enlarged epiglottis and swelling arytenoids. Highly suspicious of early-PTLD, he was treated with reduction of immunosuppression, but no improvement on his larynx was observed. Laser ablation of swelling arytenoids worked. Surgical debulking is effective to ease an airway obstruction in cases of PTLD.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Kyoto University Postgraduate School of Medicine, Kyoto, Japan. knishimura@ent.kuhp.kyoto-u.ac.jp
authors.forename: Koji
authors.initials: K
authors.lastname: Nishimura
authors.forename: Koichi
authors.initials: K
authors.lastname: Omori
authors.forename: Hironori
authors.initials: H
authors.lastname: Haga
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Fujimoto
authors.forename: Juichi
authors.initials: J
authors.lastname: Ito
mesh_terms: D000402:Airway Obstruction / Q000209:etiology* / Q000601:surgery*; D002648:Child; D006801:Humans; D007564:Japan; D007818:Laryngeal Diseases / Q000209:etiology* / Q000601:surgery*; D053685:Laser Therapy; D016031:Liver Transplantation / Q000009:adverse effects; D008232:Lymphoproliferative Disorders / Q000209:etiology*; D008297:Male; D016896:Treatment Outcome