title: A case of invasive thymoma with endobronchial growth.
abstract: We report a rare case of invasive thymoma with endobronchial growth in a 69- year-old woman. Chest CT revealed an ill-defined mass with a calcified lesion in the anterior mediastinum and coin lesion in the bilateral lung fields. An endobronchial polypoid tumor in the right B3 bronchus was found by bronchoscopic examination. A biopsy specimen obtained from the polypoid tumor suggested thymoma. After radiotherapy combined with chemotherapy, thymothymectomy combined with right upper lobectomy through median sternotomy was performed. The surgical specimen revealed that the tumor extended nodularly, not only into the pulmonary parenchyma but also into the bronchial lumen. We performed an added chemotherapy for lung metastasis, and partial resection of lung with video-assisted thoracoscopic surgery (VATS) was done. Now she is alive and disease-free.
authors.affiliation: From Department of Thoracic Surgery, National Hospital Organization Tokyo Hospital, Tokyo, Japan.
authors.forename: Motoki
authors.initials: M
authors.lastname: Sakuraba
authors.forename: Yuzo
authors.initials: Y
authors.lastname: Sagara
authors.forename: Atsuhisa
authors.initials: A
authors.lastname: Tamura
authors.forename: Zaizen
authors.initials: Z
authors.lastname: Park
authors.forename: Akira
authors.initials: A
authors.lastname: Hebisawa
authors.forename: Hikotaro
authors.initials: H
authors.lastname: Komatsu
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor; D001980:Bronchi / Q000473:pathology*; D001984:Bronchial Neoplasms / Q000473:pathology*; D001999:Bronchoscopy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008482:Mediastinum / Q000000981:diagnostic imaging / Q000473:pathology; D020775:Thoracic Surgery, Video-Assisted; D013934:Thymectomy; D013945:Thymoma / Q000473:pathology* / Q000601:surgery; D013953:Thymus Neoplasms / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor