title: [Headache and impaired consciousness due to the spontaneous intracranial hypotension syndrome].
abstract: A 51-year-old man presented with a 6-week history of progressive headache, confusion and ataxic gate. The symptoms were not preceded by trauma or lumbar puncture. A CT-scan of the brain revealed bilateral subdural fluid accumulation and hyperdensities in the subarachnoid space. In view of the signs of a subarachnoid haemorrhage, angiography was performed but showed no indications of an aneurysm. An MRI-scan of the head revealed abnormalities in line with intracranial hypotension. CT-myelography of the whole spine revealed a cerebrospinal fluid leak at the level of the fifth and sixth thoracic vertebrae. The patient recovered completely after placement of an epidural blood patch at this level. Spontaneous intracranial hypotension shows clinical similarities with the symptoms following a lumbar puncture. In most cases it can be treated by conservative measures. However, invasive measures are sometimes necessary to close the defect in the meninges.
authors.affiliation: Academisch Medisch Centrum/Universiteit van Amsterdam, Meibergdreefg, 1105 AZ Amsterdam. m.weisfelt@amc.uva.nl
authors.forename: M
authors.initials: M
authors.lastname: Weisfelt
authors.forename: Rvan
authors.initials: R
authors.lastname: den Munckhof
authors.forename: G J
authors.initials: GJ
authors.lastname: Bouma
authors.forename: C B
authors.initials: CB
authors.lastname: Majoie
authors.forename: D A
authors.initials: DA
authors.lastname: Bosch
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D006261:Headache / Q000209:etiology; D006801:Humans; D019585:Intracranial Hypotension / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009192:Myelography; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome