title: Contemporary series of morbidity and mortality after lower limb amputation.
abstract: OBJECTIVE
  This study was performed in order to assess morbidity and mortality associated with major lower extremity amputation according to an extensive complication registration system used in our hospital.
  
  
  METHODS
  All consecutive patients who underwent lower limb major extremity amputation were included from January 1996 until December 2002. Complications were prospectively registered according to our standard complication registration system.
  
  
  RESULTS
  In 97 patients 122 amputations were performed including 45 above (AKA) and 77 below (BKA) knee amputations. The conversion rate from below to above knee amputation was 14%. In 65 patients 107 complications occurred (67%). The incidence of wound infection was 10% in the BKA group and 2% in the AKA group. The most frequently reported complications were pressure sores (8%) or originating from the urinary tract (13%). The hospital mortality for BKA was 9% and for AKA 18%. Long-term survival was 62% at 1 year, 50% at 2 years and 29% at 5 years.
  
  
  CONCLUSIONS
  An extensive registration system provides us with a detailed insight into the incidence, consequence and cause of complications. Major lower extremity amputations are still associated with considerable morbidity and mortality.
authors.affiliation: Department of Surgery, Red Cross Hospital, 2566 MJ Hague, The Netherlands. a.ploeg@jkz-rkz.nl
authors.forename: A J
authors.initials: AJ
authors.lastname: Ploeg
authors.forename: J-W
authors.initials: JW
authors.lastname: Lardenoye
authors.forename: M-P F M
authors.initials: MP
authors.lastname: Vrancken Peeters
authors.forename: P J
authors.initials: PJ
authors.lastname: Breslau
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000671:Amputation, Surgical / Q000009:adverse effects* / Q000706:statistics & numerical data; D002423:Cause of Death; D015897:Comorbidity; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D007511:Ischemia / Q000401:mortality / Q000601:surgery*; D007866:Leg / Q000098:blood supply* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality*; D011446:Prospective Studies; D012042:Registries; D012307:Risk Factors; D016019:Survival Analysis