title: Regulation of the stress response in early vertebrates.
abstract: The acute stress response is a key regulatory system for the maintenance of homeostatic equilibrium that is activated upon an imminent or ongoing disturbance of the "milieu interieur". In general, the stress response in bony fish is similar to that of mammals. The recent cloning and characterization of corticotropin-releasing hormone-binding protein (CRH-BP) in carp (Cyprinus carpio L.) reflects the conservation of the CRH signaling system throughout vertebrates. Now, we can start to investigate the processes that are mediated by the factors that make up this system. The stress response is only one of these processes.
authors.affiliation: Department of Animal Physiology, Institute of Neuroscience, Radboud University Nijmegen, the Netherlands.
authors.forename: Mark O
authors.initials: MO
authors.lastname: Huising
authors.forename: Juriaan R
authors.initials: JR
authors.lastname: Metz
authors.forename: Aurelia F
authors.initials: AF
authors.lastname: De Mazon
authors.forename: B M Lidy
authors.initials: BM
authors.lastname: Verburg-van Kemenade
authors.forename: Gert
authors.initials: G
authors.lastname: Flik
mesh_terms: D000818:Animals; D002347:Carps / Q000378:metabolism*; D002352:Carrier Proteins / Q000235:genetics / Q000502:physiology; D003346:Corticotropin-Releasing Hormone / Q000378:metabolism / Q000502:physiology; D006801:Humans; D010903:Pituitary Gland, Anterior / Q000378:metabolism; D013312:Stress, Physiological / Q000378:metabolism*
chemical_list: D002352:Carrier Proteins; C067133:corticotropin releasing factor-binding protein; D003346:Corticotropin-Releasing Hormone