title: [Adult renal neoplasms in the material of the Pathology Department of the Szeged University].
abstract: OBJECTIVE
  The authors investigated the frequencies of the various histological types of adult renal tumours.
  
  
  METHODS
  The slides of 469 nephrectomies performed in the Department of Urology, Szeged University between 1990 and 2003 were revised according to the 1997 Heidelberg and 2004 WHO classification schemes.
  
  
  RESULTS
  86.7% of all the tumours (n = 407) were malignant. Among the malignant tumours, the frequency of renal cell carcinomas was 91.1% (n = 371). 88.4% of the renal cell carcinomas (n = 328) were of conventional type, 5.6% (n = 21) were papillary and 4% (n = 15) were chromophobe. The authors observed 3 Bellini duct, 1 mucinous tubular and 3 non-classifiable carcinomas, with a combined incidence of 1.8%. 84.5% of the conventional carcinomas were clear cell (n = 277), 8.8% were eosinophilic granular (n = 29), 3.9% were multilocular cystic (n = 13) and 2.7% were sarcomatoid carcinomas (n = 9). The median age of the patients with conventional carcinoma was 60 (median, range: 25-84), in the papillary group it was 62 (43-78), and in the chromophobe group was 59 (17-77). The median age of patients affected by transitional cell carcinoma was 64 (range: 45-81). As far as benign tumours are concerned (13.2%, n = 62), oncocytomas (n = 37, 7.8% of all the tumours) affected mainly females, whereas angiomyolipomas (n = 21, 4.4% of all the tumours) occurred in females only. In 13 oncocytoma cases, the tumours were initially diagnosed as malignant.
  
  
  CONCLUSIONS
  Adult malignant renal tumours affect mainly patients around the age of 60. The commonest diagnosis was clear cell carcinoma of conventional type. The incidence of clear cell carcinoma was 5% higher than that reported in the literature (84.5% vs 70-80%) whereas that of papillary carcinoma was 5% lower (5% vs 10-15%). In comparison with the literature data, oncocytomas were relatively common (8% instead of 3%), and not rarely, it was difficult to distinguish them from renal cell carcinomas.
authors.affiliation: Szegedi Tudományegyetem, Altalános Orvostudományi Kar, Patológiai Intézet.
authors.forename: István
authors.initials: I
authors.lastname: Németh
authors.forename: Farkas
authors.initials: F
authors.lastname: Sükösd
authors.forename: László
authors.initials: L
authors.lastname: Béli
authors.forename: Attila
authors.initials: A
authors.lastname: Kiss
authors.forename: László
authors.initials: L
authors.lastname: Pajor
authors.forename: Tivadar
authors.initials: T
authors.lastname: Mikó
authors.forename: Béla
authors.initials: B
authors.lastname: Iványi
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000453:epidemiology / Q000473:pathology; D000238:Adenoma, Chromophobe / Q000453:epidemiology / Q000473:pathology; D018249:Adenoma, Oxyphilic / Q000453:epidemiology / Q000473:pathology; D000328:Adult; D000368:Aged; D018207:Angiomyolipoma / Q000453:epidemiology / Q000473:pathology; D002277:Carcinoma / Q000145:classification / Q000453:epidemiology* / Q000473:pathology* / Q000601:surgery; D002291:Carcinoma, Papillary / Q000453:epidemiology / Q000473:pathology; D002292:Carcinoma, Renal Cell / Q000453:epidemiology / Q000473:pathology; D002295:Carcinoma, Transitional Cell / Q000453:epidemiology / Q000473:pathology; D005260:Female; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D007680:Kidney Neoplasms / Q000453:epidemiology* / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy