title: Circadian clocks are seeing the systems biology light.
abstract: Circadian rhythms are those biological rhythms that have a periodicity of around 24 hours. Recently, the generation of a circadian transcriptional network -- compiled from RNA-expression and promoter-element analysis and phase information -- has led to a better understanding of the gene-expression patterns that regulate the precise 24-hour clock.
authors.affiliation: The Scripps Research Institute, 5353 Parkside Drive, Jupiter, FL 33458, USA.
authors.forename: Kevin R
authors.initials: KR
authors.lastname: Hayes
authors.forename: Julie E
authors.initials: JE
authors.lastname: Baggs
authors.forename: John B
authors.initials: JB
authors.lastname: Hogenesch
mesh_terms: D000818:Animals; D002940:Circadian Rhythm / Q000235:genetics*; D025461:Feedback, Physiological; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D008322:Mammals / Q000235:genetics; D008957:Models, Genetic; D011401:Promoter Regions, Genetic / Q000235:genetics; D012313:RNA / Q000378:metabolism; D050436:Regulatory Elements, Transcriptional; D049490:Systems Biology
chemical_list: D012313:RNA