[CT findings in patients with chronic thrombembolic pulmonary hypertension].
Chronic thromboembolic pulmonary hypertension (CTEPH) is thought to be a rare complication of pulmonary embolism. However, it was recently demonstrated that CTEPH is more common than previously thought after pulmonary embolism. Without treatment, CTEPH is associated with a very high mortality rate. Making the correct diagnosis early is essential, because there is a potential curative treatment in the form of pulmonary thromboendarterectomy (PTE). Because of the unspecific clinical symptoms of CTEPH, the different imaging modalities play a crucial role in diagnosis making. Since the introduction of the multidetector CT technology, CT has become an important part in the diagnostic work up of pulmonary embolism and CTEPH and is often used as a first-line diagnostic tool. CT is not only a reliable tool for the diagnosis of CTEPH, but also is helpful in estimating the operability of these patients. PTE is still associated with a mortality rate of about 10%. Particularly an insufficient decrease of the pulmonary vascular resistance after PTE leads to a very high mortality rate. Therefore, it is crucial to correlate the degree of the surgical accessible obstruction of the pulmonary vasculature with the degree of pulmonary hypertension in deciding for or against PTE. The aim of this review is to describe the CT findings in patients with CTEPH and their use in differentiating CTEPH from other diseases like acute pulmonary embolism and primary pulmonary hypertension. Moreover, the correlation of different CT imaging features with surgical success after PTE will be discussed.
Heinrich
Marc
M
Radiologische Klinik, Abteilung für Radiodiagnostik, Universitätsklinikum des Saarlandes, Homburg. ramhei@uniklinik-saarland.de
Grgic
Aleksandar
A
Tscholl
Dietmar
D
Heckmann
Martina
M
Kramann
Bernhard
B
Schäfers
Hans-Joachim
HJ
Uder
Michael
M
D000792:Angiography; D002908:Chronic Disease; D003937:Diagnosis, Differential; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging*; D007089:Image Enhancement; D007238:Infarction / Q000000981:diagnostic imaging; D008168:Lung / Q000098:blood supply / Q000000981:diagnostic imaging; D011379:Prognosis; D011651:Pulmonary Artery / Q000000981:diagnostic imaging; D011655:Pulmonary Embolism / Q000150:complications / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity; D036542:Tomography, Spiral Computed