title: Susceptibility of West African Dwarf goats and WAD x Saanen crosses to experimental infection with Trypanosoma congolense.
abstract: West African Dwarf goats (WADs) and their Saanen crosses were experimentally infected with Trypanosoma congolense. No significant differences were found between trypanosome parasitaemia and antibody response of the crossbred and WAD goats. Neither the WAD goats nor the Saanen crosses were able to control the drop in PCV following trypanosome infection. The level of anaemia caused by the trypanosome infection was similar in the two breeds during the trial. Based on these findings, no difference in tolerance or susceptibility to T. congolense could be demonstrated between the WAD goats and their Saanen crosses. Although the weight of all goats increased during the trial, the crosses gained significantly more weight than the WAD goats. The trypanosome infection reduced the growth rate of both breeds, but this reduction was not statistically significant. Crossbreeding trypanotolerant WADs with trypanosusceptible Saanen goats might, therefore, be an effective means of increasing productivity.
authors.affiliation: International Trypanotolerance Centre, PMB 14, Banjul, Gambia. sofiedhollander@yahoo.co.uk
authors.forename: S
authors.initials: S
authors.lastname: Dhollander
authors.forename: J
authors.initials: J
authors.lastname: Bos
authors.forename: S
authors.initials: S
authors.lastname: Kora
authors.forename: M
authors.initials: M
authors.lastname: Sanneh
authors.forename: M
authors.initials: M
authors.lastname: Gaye
authors.forename: S
authors.initials: S
authors.lastname: Leak
authors.forename: D
authors.initials: D
authors.lastname: Berkvens
authors.forename: S
authors.initials: S
authors.lastname: Geerts
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001835:Body Weight; D003433:Crosses, Genetic; D004133:Diminazene / Q000627:therapeutic use; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D005714:Gambia; D020022:Genetic Predisposition to Disease; D015511:Goat Diseases / Q000235:genetics / Q000469:parasitology* / Q000517:prevention & control*; D006041:Goats; D006400:Hematocrit / Q000662:veterinary; D008297:Male; D008858:Microscopy, Phase-Contrast / Q000662:veterinary; D018512:Parasitemia / Q000469:parasitology / Q000662:veterinary; D014348:Trypanosoma congolense / Q000254:growth & development*; D014353:Trypanosomiasis, African / Q000235:genetics / Q000469:parasitology / Q000517:prevention & control* / Q000662:veterinary*
chemical_list: D000913:Antibodies, Protozoan; D000981:Antiprotozoal Agents; D004133:Diminazene