title: Novel techniques to improve split-thickness skin graft viability during vulvo-vaginal reconstruction.
abstract: BACKGROUND
  Split-thickness skin grafts are often utilized for vulvo-vaginal reconstruction. Unfortunately, infection and sloughing may occur in up to 22% of patients with standard techniques especially at irradiated recipient sites.
  
  
  METHODS
  We report seven cases of vulvo-vaginal reconstruction using split-thickness skin grafts. In this series, we used fibrin tissue adhesives with and without vacuum-assisted closure devices to augment graft adherence and viability. We briefly describe the clinical history, surgical techniques, and outcomes of the cohort.
  
  
  CONCLUSIONS
  Fibrin tissue adhesives and wound vacuum-assisted closure devices may improve the viability of split-thickness skin grafts during vulvo-vaginal reconstruction.
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Walter Reed Army Medical Center, 6900 Georgia Avenue NW, Washington, DC 20307, USA.
authors.forename: Louis A
authors.initials: LA
authors.lastname: Dainty
authors.forename: Jason J
authors.initials: JJ
authors.lastname: Bosco
authors.forename: John W
authors.initials: JW
authors.lastname: McBroom
authors.forename: William E
authors.initials: WE
authors.lastname: Winter
authors.forename: G Scott
authors.initials: GS
authors.lastname: Rose
authors.forename: John C
authors.initials: JC
authors.lastname: Elkas
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D019651:Plastic Surgery Procedures / Q000379:methods*; D016038:Skin Transplantation; D014621:Vagina / Q000601:surgery*; D014844:Vulva / Q000601:surgery*
chemical_list: D015718:Fibrin Tissue Adhesive