title: Informatics in radiology (infoRAD): new tools for computer assistance in thoracic CT part 2. Therapy monitoring of pulmonary metastases.
abstract: Owing to the rapid development of scanner technology, thoracic computed tomography (CT) offers new possibilities but also faces enormous challenges with respect to the quality of computer-assisted diagnosis and therapy planning. In the framework of the Virtual Institute for Computer Assistance in Clinical Radiology cooperative research project, a software application was developed to assist the radiologist in the analysis of thoracic CT data for the purpose of evaluating the response to tumor therapy. The application provides follow-up support for monitoring of tumor therapy by means of volumetric quantification of tumors and temporal registration. In addition, anatomically adequate three-dimensional visualization techniques for convenient examination of large data sets are included. With close cooperation between computer scientists and radiologists, the application was tested and optimized to achieve a high degree of usability. Several clinical studies were carried out, the results of which indicated that the application improves therapy monitoring with respect to accuracy and time required.
authors.affiliation: MeVis Center for Medical Diagnostic Systems and Visualization, Universitaetsallee 29, 28359 Bremen, Germany. bornemann@mevis.de
authors.forename: Lars
authors.initials: L
authors.lastname: Bornemann
authors.forename: Jan-Martin
authors.initials: JM
authors.lastname: Kuhnigk
authors.forename: Volker
authors.initials: V
authors.lastname: Dicken
authors.forename: Stephan
authors.initials: S
authors.lastname: Zidowitz
authors.forename: Bernd
authors.initials: B
authors.lastname: Kuemmerlen
authors.forename: Stefan
authors.initials: S
authors.lastname: Krass
authors.forename: Heinz-Otto
authors.initials: HO
authors.lastname: Peitgen
authors.forename: Berthold B
authors.initials: BB
authors.lastname: Wein
authors.forename: Henning
authors.initials: H
authors.lastname: Schubert
authors.forename: Hoen-oh
authors.initials: HO
authors.lastname: Shin
authors.forename: Dag
authors.initials: D
authors.lastname: Wormanns
mesh_terms: D000465:Algorithms; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary* / Q000628:therapy; D011857:Radiographic Image Interpretation, Computer-Assisted; D014057:Tomography, X-Ray Computed / Q000379:methods*