Pre-pro-somatostatin-III may have cortistatin-like functions in fish.
This study analyzes daily changes in the expression of somatostatin precursors PSS-I and PSS-III (structurally related to cortistatin) in the goldfish brain. The results indicate that PSS-I expression correlates with the light cycle only in optic tectum-thalamus (OT-Tha). PSS-III expression correlates with the light cycle in telencephalon-preoptic area (Tel-POA) and OT-Tha. In Tel-POA, PSS-III reaches a minimum level at the beginning of the active phase and a maximum level late in this phase. These results suggest that PSS-I in OT-Tha and PSS-III in Tel-POA and OT-Tha could be involved in the control of the activity cycles in goldfish.
Canosa
Luis Fabián
LF
Department of Biological Sciences, University of Alberta, Edmonton, Canada.
Peter
Richard Ector
RE
D000818:Animals; D002940:Circadian Rhythm / Q000235:genetics / Q000502:physiology; D006054:Goldfish / Q000235:genetics / Q000502:physiology*; D009479:Neuropeptides / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D011498:Protein Precursors / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D013004:Somatostatin / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D029961:Zebrafish Proteins / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology
D009479:Neuropeptides; D011498:Protein Precursors; D029961:Zebrafish Proteins; C504314:cort protein, zebrafish; C099323:cortistatin; D013004:Somatostatin; C028456:prosomatostatin