title: [Tyrosine kinase inhibitors in tumor therapy--part 1. Molecular and genetic fundamentals].
authors.affiliation: Abteilung Innere Medizin II, Medizinische Universitätsklinik Freiburg. grimm@med1.ukl.uni-freiburg.de
authors.forename: C F
authors.initials: CF
authors.lastname: Grimm
authors.forename: H E
authors.initials: HE
authors.lastname: Blum
authors.forename: M
authors.initials: M
authors.lastname: Geissler
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001549:Benzamides; D019281:Dimerization; D004789:Enzyme Activation / Q000235:genetics / Q000502:physiology; D006133:Growth Substances / Q000235:genetics / Q000378:metabolism; D006801:Humans; D000068877:Imatinib Mesylate; D009369:Neoplasms / Q000098:blood supply / Q000188:drug therapy* / Q000235:genetics; D009389:Neovascularization, Pathologic; D010879:Piperazines / Q000627:therapeutic use; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D011743:Pyrimidines / Q000627:therapeutic use; D020794:Receptor Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000378:metabolism*; D017978:Receptors, Growth Factor / Q000235:genetics / Q000378:metabolism; D040262:Receptors, Vascular Endothelial Growth Factor / Q000502:physiology; D015398:Signal Transduction / Q000235:genetics
chemical_list: D000911:Antibodies, Monoclonal; D000970:Antineoplastic Agents; D001549:Benzamides; D006133:Growth Substances; D010879:Piperazines; D047428:Protein Kinase Inhibitors; D011743:Pyrimidines; D017978:Receptors, Growth Factor; D000068877:Imatinib Mesylate; D011505:Protein-Tyrosine Kinases; D020794:Receptor Protein-Tyrosine Kinases; D040262:Receptors, Vascular Endothelial Growth Factor