[Alopecia areata universalis and disseminated mollusca contagiosa in atopic dermatitis. Hair re-growth during treatment with interferon gamma--therapeutic effect or coincidence?].
A 35-year-old woman presented with severe recalcitrant atopic dermatitis, in association with disseminated mollusca contagiosa and alopecia areata universalis. After several weeks of systemic interferon gamma, which was administered subcutaneously,the viral infection cleared and, surprisingly, four weeks after starting treatment hair re-growth was observed. Complete remission of alopecia areata was documented few weeks later and persists. After four cycles of high-dose intravenous immunoglobulin, a sustained remission of the atopic dermatitis was achieved.
Hein
Ulrike
U
Dermatologische Abteilung des Sozialmedizinischen Zentrums-Ost Donauspital, Wien, Austria. ulrike.hein@wienkav.at
Anegg
Barbara
B
Volc-Platzer
Beatrix
B
D000328:Adult; D000506:Alopecia Areata / Q000209:etiology*; D000998:Antiviral Agents / Q000008:administration & dosage / Q000627:therapeutic use; D003876:Dermatitis, Atopic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D006197:Hair / Q000254:growth & development*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage; D007279:Injections, Subcutaneous; D007371:Interferon-gamma / Q000008:administration & dosage / Q000627:therapeutic use; D008976:Molluscum Contagiosum / Q000188:drug therapy / Q000209:etiology*; D013997:Time Factors; D016896:Treatment Outcome
D000998:Antiviral Agents; D016756:Immunoglobulins, Intravenous; D007371:Interferon-gamma