Suppress Winfree turbulence by local forcing excitable systems.
The occurrence of Winfree turbulence is currently regarded as one of the principal mechanisms underlying cardiac fibrillation. We develop a local stimulation method that suppresses Winfree turbulence in three-dimensional excitable media. We find that Winfree turbulence can be effectively suppressed by locally injecting periodic signals to only a very small subset (around some surface region) of total space sites. Our method for the first time demonstrates the effectiveness of local low-amplitude periodic excitations in suppressing turbulence in 3D excitable media and has fundamental improvements in efficiency, convenience, and turbulence suppression speed compared with previous strategies. Therefore, it has great potential for developing into a practical low-amplitude defibrillation approach.
Zhang
Hong
H
Zhejiang Institute of Modern Physics and Department of Physics, Zhejiang University, Hangzhou 310027, China.
Cao
Zhoujian
Z
Wu
Ning-Jie
NJ
Ying
He-Ping
HP
Hu
Gang
G
D000818:Animals; D003198:Computer Simulation; D004554:Electric Countershock / Q000379:methods; D004574:Electromagnetic Fields; D006329:Heart Conduction System / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D008959:Models, Neurological; D017711:Nonlinear Dynamics; D009435:Synaptic Transmission / Q000502:physiology*