title: Additional dose constraints for analytical beam weighting optimization in IMRT.
abstract: This work presents an improvement to an algorithm for analytical beam weighting optimization where a flexible objective function, which considers 'importance factors' for each anatomical region and 'allowed deviations' from the prescribed dose, is defined. This upgrading allows forcing the mean value of the dose distribution to be the desired value, by using Lagrange multipliers. A real case is presented to show the effect of this change.
authors.affiliation: Servicio de Radiofísica, Hospital Virgen Macarena, Sevilla, Spain.
authors.forename: Rafael
authors.initials: R
authors.lastname: Arráns
authors.forename: María Isabel
authors.initials: MI
authors.lastname: Gallardo
authors.forename: Joan
authors.initials: J
authors.lastname: Roselló
authors.forename: Francisco
authors.initials: F
authors.lastname: Sánchez-Doblado
mesh_terms: D000465:Algorithms; D019583:Dose Fractionation, Radiation; D006801:Humans; D008962:Models, Theoretical; D009369:Neoplasms / Q000532:radiotherapy; D011878:Radiotherapy / Q000379:methods*