title: Antibacterial potential from Indian Suregada angustifolia.
abstract: Phytochemical analysis of the leaves from Indian Suregada angustifolia (Baill. ex Muell. Arg.) Airy Shaw (Euphorbiaceae) resulted in the isolation and identification of six known compounds, viz. friedelin, epi-friedelinol, n-octacosanol, alpha-amyrin, beta-sitosterol and beta-sitosterol-3-beta-D-glucopyranoside. Aqueous (room temperature, boiled and autoclaved) and various solvent (methanol, chloroform and hexane) extracts of leaves were tested against 12 human pathogenic bacteria by the agar well-diffusion method. Aqueous extracts did not express any activity. Antibacterial activity was recorded in the order of methanol, hexane and chloroform extracts. Maximum activity recorded against Staphylococcus aureus (skin infections) in methanol and hexane extracts and moderate activity recorded against diarrhoea causing bacteria, Vibrio vulnificus (hexane extract) and Vibrio cholerae (chloroform extract).
authors.affiliation: Sri Paramakalyani Centre for Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi 627 412, Tamil Nadu, India.
authors.forename: M
authors.initials: M
authors.lastname: Venkatesan
authors.forename: M B
authors.initials: MB
authors.lastname: Viswanathan
authors.forename: N
authors.initials: N
authors.lastname: Ramesh
authors.forename: P
authors.initials: P
authors.lastname: Lakshmanaperumalsamy
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002725:Chloroform / Q000737:chemistry; D006586:Hexanes / Q000737:chemistry; D006801:Humans; D007194:India; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000254:growth & development; D008826:Microbial Sensitivity Tests / Q000379:methods; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D011514:Proteus vulgaris / Q000187:drug effects / Q000254:growth & development; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development; D029843:Suregada / Q000737:chemistry*; D014734:Vibrio cholerae / Q000187:drug effects / Q000254:growth & development; D014736:Vibrio parahaemolyticus / Q000187:drug effects / Q000254:growth & development
chemical_list: D000900:Anti-Bacterial Agents; D006586:Hexanes; D010936:Plant Extracts; D002725:Chloroform