title: Spectral analysis of laser-induced ultraweak delayed luminescence in cultured normal and tumor human cells: temperature dependence.
abstract: The emission spectrum of ultraviolet A laser induced ultraweak delayed luminescence in cell cultures of mammalian cells depended on the temperature during irradiation and photonic measurements. A new method using a sophisticated photomultiplier system was developed in order to find differences between normal and tumor cells. The maximal peak of the emitted light for cultures measured at low temperature of 10 degrees C was near 510 nm in the green visible region while following irradiation at 32 degrees C this maximum was shifted to yellow-orange at 570 nm both in normal and melanoma cells. Overall, this ultraweak photonic model of cultured cells provides to be a new and powerful non-invasive tool for developing new strategies in skin cancer detection.
authors.affiliation: Dipartimento di Metodologie Fisiche e Chimiche per l'Ingegneria, University of Catania, v. le Andrea Doria 6, I95125 Catania, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Musumeci
authors.forename: Lee Ann
authors.initials: LA
authors.lastname: Applegate
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Privitera
authors.forename: Agata
authors.initials: A
authors.lastname: Scordino
authors.forename: Salvatore
authors.initials: S
authors.lastname: Tudisco
authors.forename: Hugo J
authors.initials: HJ
authors.lastname: Niggli
mesh_terms: D000328:Adult; D045744:Cell Line, Tumor; D002478:Cells, Cultured; D002648:Child; D006801:Humans; D007834:Lasers; D049449:Luminescence; D008163:Luminescent Measurements; D008297:Male; D008875:Middle Aged; D013057:Spectrum Analysis; D013696:Temperature