Impact of right lobe with middle hepatic vein graft in living-donor liver transplantation.
Technical improvements in adult-to-adult living-donor liver transplantation (LDLT) have led to the use of right-lobe grafts to overcome the problems encountered with 'small-for-size grafts'. The major controversy remains that the venous drainage from anterior segment substantially depends on tributaries of the middle hepatic vein (MHV), and deprivation of such tributaries may critically influence the postoperative graft function. Right-lobe grafts with MHV could resolve the potential problem of congestion in anterior segment. From December 2000 to January 2004, we performed 217 right-lobe LDLTs for adult patients. Of these, 40 patients received a right lobe with MHV graft (18.4%). The overall cumulative 3-year graft survival rate of a right lobe with (n = 40) and without MHV (n = 177) was 86.2% and 74.8% (p = NS). The proximal side of the MHV and the drainage vein of segment IV to the MHV (the left medial superior vein) were preserved in 24 patients. All of them needed venous interposition graft for anastomosis. All patients had a patent right hepatic vein (RHV) and MHV anastomosis during the follow-up period. We adopted the right lobe with MHV graft in 40 LDLT cases. Vein graft is essential for safe MHV anastomosis in cases which preserve proximal side of the MHV.
Kasahara
Mureo
M
Organ Transplant Unit, Department of Transplant Surgery, Kyoto University Hospital, Japan. mureo@kuhp.kyoto-u.ac.jp
Takada
Yasutsugu
Y
Fujimoto
Yasuhiro
Y
Ogura
Yasuhiro
Y
Ogawa
Kohei
K
Uryuhara
Kenji
K
Yonekawa
Yukihide
Y
Ueda
Mikiko
M
Egawa
Hiroto
H
Tanaka
Koichi
K
D000328:Adult; D000368:Aged; D005260:Female; D006085:Graft Survival; D006498:Hepatectomy / Q000379:methods; D006503:Hepatic Veins / Q000601:surgery / Q000637:transplantation*; D006801:Humans; D008102:Liver Circulation; D016031:Liver Transplantation / Q000379:methods* / Q000401:mortality; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control; D014682:Vena Cava, Inferior / Q000601:surgery