title: Effects of giant left atrium on thromboembolism after mitral valve replacement.
abstract: The aim of this study was to evaluate the incidence of thromboembolic events in patients with giant left atrium ( > 6.5 cm) after mitral valve replacement. From January 2000 to September 2002, a total of 126 patients who had undergone mitral valve replacement were divided into two groups according to the presence or absence of giant left atrium. Group A comprised 34 patients with left atrium over 6.5 cm without compression symptoms and Group B comprised 92 patients. The preoperative variables did not distinguish the patients in each group, except for atrial fibrillation; Group A 85.2% and Group B 61.9% ( p < 0.01). After mitral valve replacement, left atrium mean diameter was significantly decreased in Group A from 8.1 +/- 1.3 mm to 6.2 +/- 1.6 mm ( p < 0.01). There were no significant differences in thrombosis, hemorrhage and thromboembolism rates in both groups. Postoperative clinical and hemodynamic parameters demonstrated a positive clinical response to mitral valve replacement in patients with giant left atrium. During follow-up no direct relationship between thromboembolism and giant left atrium was evident.
authors.affiliation: Cardiovascular Surgery Department, Van Yuksek Ihtisas Hospital, Van, Turkey. vkutay@yahoo.com
authors.forename: Veysel
authors.initials: V
authors.lastname: Kutay
authors.forename: Kaan
authors.initials: K
authors.lastname: Kirali
authors.forename: Hasan
authors.initials: H
authors.lastname: Ekim
authors.forename: Cevat
authors.initials: C
authors.lastname: Yakut
mesh_terms: D000293:Adolescent; D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D006332:Cardiomegaly / Q000150:complications*; D005260:Female; D006274:Health Facility Moving; D006325:Heart Atria / Q000473:pathology; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve; D012086:Reoperation; D013923:Thromboembolism / Q000209:etiology*; D015912:Thrombolytic Therapy
chemical_list: D000925:Anticoagulants