title: [Use of capillary isotachophoresis for the determination of pheniramine in granulated powders].
abstract: The method of capillary isotachophoresis was used to assay pheniramine in granulated powders. Several electrolyte systems of different composition and different pH were tested. Two electrolyte systems were selected for the validation of the method and pheniramine determination in real samples. Precision, accuracy, linearity, robustness, and selectivity of the ITP method for both electrolyte systems were evaluated. The pre-treatment of samples prior to analysis consisted in dissolving pheniramine-containing granulated powder in demineralized water and subsequent diluting with demineralized water to required concentration.
authors.affiliation: Farmaceutická fakulta Univerzity Komenského v Bratislave, Katedra farmaceutickej analýzy a nukleárnej farmácie. kubacak@fpharm.uniba.sk
authors.forename: P
authors.initials: P
authors.lastname: Kubacák
authors.forename: P
authors.initials: P
authors.lastname: Mikus
authors.forename: I
authors.initials: I
authors.lastname: Valásková
authors.forename: E
authors.initials: E
authors.lastname: Havránek
mesh_terms: D018926:Anti-Allergic Agents / Q000032:analysis*; D019075:Electrophoresis, Capillary; D006634:Histamine H1 Antagonists / Q000032:analysis*; D010632:Pheniramine / Q000032:analysis*; D011208:Powders
chemical_list: D018926:Anti-Allergic Agents; D006634:Histamine H1 Antagonists; D011208:Powders; D010632:Pheniramine