title: [Diagnosis and medical treatment of pouchitis in ileal pouch-anal anastomosis in patients with ulcerative colitis].
abstract: Pouchitis is a common and long-term complication of ileal pouch-anal anastomosis in patients with underlying ulcerative colitis. Combination with clinical symptoms, endoscopic and histopathological findings are required to make accurate diagnosis. Ciprofloxacin and metronidazole are effective in patients with acute pouchitis. Probiotics may be useful in maintaining regression and preventing from remission. Immunomodulating agents are also useful in chronic pouchitis.
authors.affiliation: Department of Gastroenterology, The Third Division of Internal Medicine, Kansai Medical University.
authors.forename: Kazuichi
authors.initials: K
authors.lastname: Okazaki
authors.forename: Mitsunobu
authors.initials: M
authors.lastname: Matsushita
authors.forename: Seiji
authors.initials: S
authors.lastname: Kawamata
authors.forename: Masaaki
authors.initials: M
authors.lastname: Shimatani
authors.forename: Toshihito
authors.initials: T
authors.lastname: Fujii
mesh_terms: D000208:Acute Disease; D000890:Anti-Infective Agents / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000150:complications* / Q000601:surgery; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D008795:Metronidazole / Q000627:therapeutic use; D011183:Postoperative Complications; D019449:Pouchitis / Q000145:classification / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D019936:Probiotics / Q000627:therapeutic use; D016737:Proctocolectomy, Restorative; D055502:Secondary Prevention
chemical_list: D000890:Anti-Infective Agents; D007155:Immunologic Factors; D008795:Metronidazole; D002939:Ciprofloxacin