Making cell-permeable recombinant telomerase (trans-telomerase) through fusion of its catalytic subunit (hTERT) with protein transduction domains (PTD): a possible strategy to overcome replicative senescence during ex vivo culture of primary explanted cells.
Heng
Boon Chin
BC
Cao
Tong
T
D020134:Catalytic Domain; D002478:Cells, Cultured; D016922:Cellular Senescence; D006801:Humans; D008954:Models, Biological; D010539:Permeability; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry*; D015398:Signal Transduction; D019098:Telomerase / Q000493:pharmacokinetics*; D016615:Telomere
D011506:Proteins; D019098:Telomerase