Antiviral evaluation of plants from Brazilian Atlantic Tropical Forest.
The antiviral activity of six medicinal plants from Brazilian Atlantic Tropical Forest was investigated against two viruses: herpes simplex virus type 1 (HSV-1) and poliovirus type 2 (PV-2). Cuphea carthagenensis and Tillandsia usneoides extracts showed the best antiherpes activity. T. usneoides dichloromethane, ethyl acetate and n-butanol extracts, and Lippia alba n-butanol extract showed inhibition of HSV-1, strain 29R/acyclovir resistant. In addition, only L. alba ethyl acetate extract showed antipoliovirus activity. These results corroborate that medicinal plants can be a rich source of potential antiviral compounds.
Andrighetti-Fröhner
C R
CR
Laboratório de Virologia Aplicada, Universidade Federal de Santa Catarina, Campus Universitário Trindade, Florianópolis, SC, Brazil.
Sincero
T C M
TC
da Silva
A C
AC
Savi
L A
LA
Gaido
C M
CM
Bettega
J M R
JM
Mancini
M
M
de Almeida
M T R
MT
Barbosa
R A
RA
Farias
M R
MR
Barardi
C R M
CR
Simões
C M O
CM
D000998:Antiviral Agents / Q000737:chemistry / Q000494:pharmacology*; D001938:Brazil; D024882:Drug Resistance, Viral; D018259:Herpesvirus 1, Human / Q000187:drug effects*; D019684:Magnoliopsida / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D017955:Poliovirus / Q000187:drug effects*
D000998:Antiviral Agents; D010936:Plant Extracts