title: Does topical lidocaine with adrenaline have an effect on morbidity in pediatric tonsillectomy?
abstract: OBJECTIVE
  To evaluate the efficacy of lidocaine with adrenaline on post-operative morbidity in pediatric patients after tonsillectomy.
  
  
  METHODS
  A double blind prospective randomized controlled clinical study.
  
  
  METHODS
  The study is consisting of two groups of pediatric patients following tonsillectomy performed in a university hospital. One group received lidocaine with adrenaline soaked swabs packed in their tonsillar fossae while the control group received saline-soaked swabs. Chi-square and two-tailed unpaired Student's t-tests were used to compare the two independent groups. p<0.05 was accepted as statistically significant.
  
  
  RESULTS
  No significant pain-relieving effect was seen in the lidocaine with adrenaline group (p>0.05) and also the other post-operative parameters such as nausea, fever, vomiting, odor, bleeding, otalgia and trismus were not statistically different between the two groups based on chi-square analysis (p>0.05). There were no complications associated with lidocaine and adrenaline.
  
  
  CONCLUSIONS
  We suggest that application of topical lidocaine with adrenaline seems to be a safe and easy medication for local anesthetic use. However, in our study, lidocaine with adrenaline offered no advantage over placebo in the control of post-operative pain and other morbidity related factors following pediatric tonsillectomy. We therefore do not recommend topical application of lidocaine with adrenaline for reducing morbidity in pediatric tonsil surgery.
authors.affiliation: University of Abant Izzet Baysal, Düzce Faculty of Medicine, Department of Otorhinolaryngology-Head and Neck Surgery, Düzce, Turkey.
authors.forename: E
authors.initials: E
authors.lastname: Egeli
authors.forename: U
authors.initials: U
authors.lastname: Harputluoglu
authors.forename: F
authors.initials: F
authors.lastname: Oghan
authors.forename: Y
authors.initials: Y
authors.lastname: Demiraran
authors.forename: E
authors.initials: E
authors.lastname: Guclu
authors.forename: O
authors.initials: O
authors.lastname: Ozturk
mesh_terms: D000293:Adolescent; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D004837:Epinephrine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D010149:Postoperative Pain / Q000209:etiology / Q000517:prevention & control*; D011446:Prospective Studies; D013997:Time Factors; D014068:Tonsillectomy / Q000009:adverse effects*; D017211:Treatment Failure; D014662:Vasoconstrictor Agents / Q000008:administration & dosage*
chemical_list: D000779:Anesthetics, Local; D014662:Vasoconstrictor Agents; D008012:Lidocaine; D004837:Epinephrine