title: Isolation and characterization of a new Vesivirus from rabbits.
abstract: This report describes the isolation, cDNA cloning, complete genome nucleotide sequence, and partial characterization of a new cultivable calicivirus isolated from juvenile feeder European rabbits (Oryctolagus cuniculus) showing symptoms of diarrhea. Absence of neutralization by type-specific neutralizing antibodies for 40 caliciviruses and phylogenetic sequence comparisons of the open reading frame 1-encoded polyprotein with those of other caliciviruses demonstrate that this new calicivirus is a putative novel member of the Vesivirus genus which is closely related to the marine calicivirus subgroup. According to its putative classification, this new virus has been named rabbit vesivirus.
authors.affiliation: Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Biotecnología de Asturias, Edificio Santiago Gascón, Campus El Cristo, Universidad de Oviedo, 33006 Oviedo, Spain.
authors.forename: José M
authors.initials: JM
authors.lastname: Martín-Alonso
authors.forename: Douglas E
authors.initials: DE
authors.lastname: Skilling
authors.forename: Lorenzo
authors.initials: L
authors.lastname: González-Molleda
authors.forename: Gloria
authors.initials: G
authors.lastname: del Barrio
authors.forename: Angeles
authors.initials: A
authors.lastname: Machín
authors.forename: Nathan K
authors.initials: NK
authors.lastname: Keefer
authors.forename: David O
authors.initials: DO
authors.lastname: Matson
authors.forename: Patrick L
authors.initials: PL
authors.lastname: Iversen
authors.forename: Alvin W
authors.initials: AW
authors.lastname: Smith
authors.forename: Francisco
authors.initials: F
authors.lastname: Parra
mesh_terms: D000818:Animals; D001483:Base Sequence; D016384:Consensus Sequence; D004279:DNA, Viral / Q000235:genetics; D016679:Genome, Viral; D008969:Molecular Sequence Data; D009838:Oligodeoxyribonucleotides / Q000737:chemistry; D016366:Open Reading Frames; D010802:Phylogeny; D012367:RNA, Viral / Q000737:chemistry / Q000235:genetics*; D011817:Rabbits / Q000821:virology*; D029342:Vesivirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*
chemical_list: D004279:DNA, Viral; D009838:Oligodeoxyribonucleotides; D012367:RNA, Viral