title: [A case of meningoencephalitis caused by Acanthamoeba sp. in Dakar].
abstract: Primary meningoencephalitis caused by free-living soil ameba is rare. We report the first diagnosed case of meningoencephalitis due to Acanthamoeba sp. in Senegal. The patient was a 24-year-old Senegalese woman hospitalized in the neurology department of Fann Hospital. Diagnosis was made 6 months after the onset of symptoms based mainly on headache with fever usually occurring in the evening, chills, and lumbar puncture demonstrating turbid fluid. Parasitological examination of cool cerebrospinal fluid sediment revealed the presence of free-living ameba trophozoites of the Acanthamoeba genus. Species determination by culture on 1.5% agar-agar enriched with Escherichia coli failed. The patient died one month following initiation of treatment using amphotericine B.
authors.affiliation: Service de Neurologie, du CHU Fann- Dakar, Sénégal. ngouille@hotmail.com
authors.forename: M
authors.initials: M
authors.lastname: Ndiaye
authors.forename: A G
authors.initials: AG
authors.lastname: Diop
authors.forename: Y
authors.initials: Y
authors.lastname: Dieng
authors.forename: M
authors.initials: M
authors.lastname: Seydi
authors.forename: F S
authors.initials: FS
authors.lastname: Diouf
authors.forename: B M
authors.initials: BM
authors.lastname: Diop
authors.forename: I P
authors.initials: IP
authors.lastname: Ndiaye
mesh_terms: D000048:Acanthamoeba; D000328:Adult; D000562:Amebiasis; D000818:Animals; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008590:Meningoencephalitis / Q000469:parasitology*; D012675:Senegal