title: Dengue fever, Hawaii, 2001-2002.
abstract: Autochthonous dengue infections were last reported in Hawaii in 1944. In September 2001, the Hawaii Department of Health was notified of an unusual febrile illness in a resident with no travel history; dengue fever was confirmed. During the investigation, 1,644 persons with locally acquired denguelike illness were evaluated, and 122 (7%) laboratory-positive dengue infections were identified; dengue virus serotype 1 was isolated from 15 patients. No cases of dengue hemorrhagic fever or shock syndrome were reported. In 3 instances autochthonous infections were linked to a person who reported denguelike illness after travel to French Polynesia. Phylogenetic analyses showed the Hawaiian isolates were closely associated with contemporaneous isolates from Tahiti. Aedes albopictus was present in all communities surveyed on Oahu, Maui, Molokai, and Kauai; no Ae. aegypti were found. This outbreak underscores the importance of maintaining surveillance and control of potential disease vectors even in the absence of an imminent disease threat.
authors.affiliation: Disease Outbreak Control Division, Hawaii State Department of Health, Honolulu, Hawaii 96813, USA. pveffler@mail.health.state.hi.us
authors.forename: Paul V
authors.initials: PV
authors.lastname: Effler
authors.forename: Lorrin
authors.initials: L
authors.lastname: Pang
authors.forename: Paul
authors.initials: P
authors.lastname: Kitsutani
authors.forename: Vance
authors.initials: V
authors.lastname: Vorndam
authors.forename: Michele
authors.initials: M
authors.lastname: Nakata
authors.forename: Tracy
authors.initials: T
authors.lastname: Ayers
authors.forename: Joe
authors.initials: J
authors.lastname: Elm
authors.forename: Tammy
authors.initials: T
authors.lastname: Tom
authors.forename: Paul
authors.initials: P
authors.lastname: Reiter
authors.forename: José G
authors.initials: JG
authors.lastname: Rigau-Perez
authors.forename: John M
authors.initials: JM
authors.lastname: Hayes
authors.forename: Kristin
authors.initials: K
authors.lastname: Mills
authors.forename: Mike
authors.initials: M
authors.lastname: Napier
authors.forename: Gary G
authors.initials: GG
authors.lastname: Clark
authors.forename: Duane J
authors.initials: DJ
authors.lastname: Gubler
mesh_terms: D003715:Dengue / Q000453:epidemiology*; D004196:Disease Outbreaks; D005260:Female; D006254:Hawaii / Q000453:epidemiology; D006801:Humans; D008297:Male; D013997:Time Factors