title: [Training and extinction of passive avoidance in mice lacking monoamine oxidase A].
abstract: The passive avoidance learning and memory trace retention in mice lacking monoamine oxidase A (MAO A) and control C3H strain were analyzed. It is shown that mice of both strains were well the passive avoidance learners. A delay of the memory trace extinction was found in lacking MAO A mice as compared with control C3H strain. Mice with a genetic MAO A knockout showed decreased amounts of transitions, rearings, looking to a dark compartment and appearing from it. These findings seem to reflect more expressed fear reaction to a dangerous compartment and increased anxiety promoting longer retention of memory trace on a high level of retrieval.
authors.forename: N I
authors.initials: NI
authors.lastname: Dubrovina
authors.forename: N K
authors.initials: NK
authors.lastname: Popova
authors.forename: M A
authors.initials: MA
authors.lastname: Gilinskiĭ
authors.forename: R A
authors.initials: RA
authors.lastname: Tomilenko
authors.forename: I
authors.initials: I
authors.lastname: Seĭf
mesh_terms: D000818:Animals; D001522:Behavior, Animal; D004924:Escape Reaction; D005108:Extinction, Psychological; D007858:Learning; D008568:Memory / Q000502:physiology*; D051379:Mice; D008809:Mice, Inbred C3H; D008995:Monoamine Oxidase / Q000172:deficiency* / Q000235:genetics*; D012153:Retention, Psychology; D013663:Teaching / Q000379:methods*
chemical_list: D008995:Monoamine Oxidase