title: Registration and fusion of CT and MRI of the temporal bone.
abstract: OBJECTIVE
  To present and evaluate a registration method to fuse complementary information of CT and MRI of the temporal bone.
  
  
  METHODS
  CT and MRI of the temporal bone of 26 patients were independently registered 4 times. A manual, iterative, intrinsic, rigid, and retrospective registration method was used. Mean CREm (consistency registration error) was calculated as a reproducibility measurement.
  
  
  RESULTS
  CREm was 0.6 mm (95% CI = 0.52-0.68 mm). T-test revealed no difference between pathologic and normal cases (t[102] = -1.71; P = 0.09). Time needed: 13 minutes. In the registered and fused datasets, important bony surgical landmarks (eg, facial nerve canal, inner ear) could be assessed in 3 dimensions relatively to tumor tissue (eg, acoustic schwannoma). Fluid distribution within partially obliterated cochleae could be assigned to either scalae.
  
  
  CONCLUSIONS
  An accurate, reproducible registration and fusion method that improves tumor surgery and cochlea implantation planning with only minor changes to the clinical workflow was presented and described. We suggest this method in selected cases.
authors.affiliation: Department of Neuroradiology, Hannover Medical School, Hannover, Germany. soenkebartling@gmx.de
authors.forename: Soenke Heinrich
authors.initials: SH
authors.lastname: Bartling
authors.forename: Kersten
authors.initials: K
authors.lastname: Peldschus
authors.forename: Thomas
authors.initials: T
authors.lastname: Rodt
authors.forename: Florian
authors.initials: F
authors.lastname: Kral
authors.forename: Herbert
authors.initials: H
authors.lastname: Matthies
authors.forename: Ron
authors.initials: R
authors.lastname: Kikinis
authors.forename: Hartmut
authors.initials: H
authors.lastname: Becker
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013701:Temporal Bone / Q000000981:diagnostic imaging* / Q000473:pathology*; D014057:Tomography, X-Ray Computed