title: Minimal invasive stabilization of osteoporotic vertebral fractures: a prospective nonrandomized comparison of vertebroplasty and balloon kyphoplasty.
abstract: OBJECTIVE
  During recent years, the benefits of balloon kyphoplasty and vertebroplasty have been frequently discussed for the treatment of osteoporotic vertebral compression fractures. Because of the lack of comparative studies, we performed an investigation to describe the mechanical effects and the impact on life quality during a follow-up period of 2 years.
  
  
  METHODS
  Patients with nonrecent fractures of vertebral bodies, ongoing bone remodeling, and major kyphotic deformity were treated with minimal invasive stabilization. The median duration of pain was 8 weeks before surgery. Because of the availability of the equipment, 28 patients were nonrandomly assigned to balloon kyphoplasty and 23 patients to vertebroplasty. The follow-up was performed 2 years after surgery.
  
  
  RESULTS
  The kyphotic wedge of the vertebral bodies was decreased 6 degrees by balloon kyphoplasty but not by vertebroplasty. With both methods, we found a rapid decrease of pain down to one-half of the preoperative value. A long-lasting effect on pain was found only after balloon kyphoplasty. In the kyphoplasty group, a decrease of the Oswestry Disability Index (ODI) score was found during the first postoperative year. After 2 years, the ODI was not different from preoperative values in both groups.
  
  
  CONCLUSIONS
  In nonrecent fractures, the reduction of the kyphotic wedge by balloon kyphoplasty was superior in decreasing pain persisting over a period of 2 years. The ability to improve disability after kyphoplasty was limited to 1 year. In nonrecent fractures, the consequences of age and osteoporosis seem to equalize the effects of the restored sagittal profile on disability but not on pain.
authors.affiliation: Department of Orthopaedic Surgery, Medical University Vienna, Wien, Austria. josef.grohs@meduniwien.ac.at
authors.forename: Josef G
authors.initials: JG
authors.lastname: Grohs
authors.forename: Michael
authors.initials: M
authors.lastname: Matzner
authors.forename: Klemens
authors.initials: K
authors.lastname: Trieb
authors.forename: Petra
authors.initials: P
authors.lastname: Krepler
mesh_terms: D000368:Aged; D004185:Disability Evaluation; D005500:Follow-Up Studies; D006801:Humans; D007738:Kyphosis / Q000000981:diagnostic imaging / Q000209:etiology; D008159:Lumbar Vertebrae; D019060:Minimally Invasive Surgical Procedures; D010024:Osteoporosis / Q000150:complications*; D010146:Pain / Q000503:physiopathology; D011446:Prospective Studies; D011788:Quality of Life; D011859:Radiography; D016103:Spinal Fractures / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery*; D013904:Thoracic Vertebrae