Comparison of myocardial perfusion after successful primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction with versus without diabetes mellitus.
Patients with diabetes mellitus (DM) have an adverse prognosis after ST-segment elevation myocardial infarction (STEMI). Whether DM was associated with impaired myocardial reperfusion after successful primary percutaneous coronary intervention for STEMI was investigated. Myocardial reperfusion was assessed by ST-segment resolution and myocardial blush grade (MBG). A total of 386 patients were studied, of whom 64 (17%) had DM. These patients more frequently had reduced MBG (20% vs 10%, p = 0.02) and incomplete ST-segment resolution (55% vs 35%, p = 0.02) compared with patients without DM. After multivariate analysis, DM was still associated with impaired ST resolution (odds ratio 2.1, p = 0.03) and reduced MBG (odds ratio 2.2, p = 0.03).
Timmer
Jorik R
JR
Department of Cardiology, Isala Klinieken, Locatie Weezenlanden, Zwolle, The Netherlands.
van der Horst
Iwan C C
IC
de Luca
Giuseppe
G
Ottervanger
Jan Paul
JP
Hoorntje
Jan C A
JC
de Boer
Menko-Jan
MJ
Suryapranata
Harry
H
Dambrink
Jan-Henk E
JH
Gosselink
Marcel
M
Zijlstra
Felix
F
van 't Hof
Arnoud W J
AW
D015906:Angioplasty, Balloon, Coronary; D003326:Coronary Circulation / Q000502:physiology*; D048909:Diabetes Complications / Q000503:physiopathology* / Q000628:therapy*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology* / Q000628:therapy*