Dengue hemorrhagic fever and acute hepatitis: a case report.
Dengue fever is the world's most important viral hemorrhagic fever disease, the most geographically wide-spread of the arthropod-born viruses, and it causes a wide clinical spectrum of disease. We report a case of dengue hemorrhagic fever complicated by acute hepatitis. The initial picture of classical dengue fever was followed by painful liver enlargement, vomiting, hematemesis, epistaxis and diarrhea. Severe liver injury was detected by laboratory investigation, according to a syndromic surveillance protocol, expressed in a self-limiting pattern and the patient had a complete recovery. The serological tests for hepatitis and yellow fever viruses were negative. MAC-ELISA for dengue was positive.
Mourão
Maria Paula Gomes
MP
Tropical Medicine Foundation of Amazonas, Laboratory of Arbovirology, University of the State of Amazonas, Av. Pedro Texeira 25, Planalto, 69040-000 Manaus, Amazonas, Brazil. mpmourao@uol.com.br
Lacerda
Marcus Vinícius Guimarães de
MV
Bastos
Michele de Souza
Mde S
Albuquerque
Bernardino Cláudio de
BC
Alecrim
Wilson Duarte
WD
D000208:Acute Disease; D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006505:Hepatitis / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D019595:Severe Dengue / Q000150:complications* / Q000175:diagnosis; D012720:Severity of Illness Index