title: Effect of garlic (Allium sativum) oil on exercise tolerance in patients with coronary artery disease.
abstract: The effect of six weeks garlic oil administration was observed on cardiac performance and exercise tolerance in 30 patients of coronary artery disease. After initial treadmill stress test, they were administered garlic oil in the dose of four capsules twice a day for 6 weeks and treadmill stress test was repeated. Garlic significantly (P<0.01) reduced heart rate at peak exercise and also significantly reduced the work load upon the heart resulting in better exercise tolerance (P<0.05) as compared to the initial test. It appears to be a good adaptogen to be utilized in patients with coronary artery disease.
authors.affiliation: Indigenous Drug Research Centre and Department of Medicine, R.N.T. Medical College, Udaipur - 313 001. skverma@datainfosys.net
authors.forename: S K
authors.initials: SK
authors.lastname: Verma
authors.forename: V
authors.initials: V
authors.lastname: Rajeevan
authors.forename: P
authors.initials: P
authors.lastname: Jain
authors.forename: A
authors.initials: A
authors.lastname: Bordia
mesh_terms: D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D003324:Coronary Artery Disease / Q000188:drug therapy* / Q000503:physiopathology; D017079:Exercise Tolerance / Q000187:drug effects* / Q000502:physiology; D005737:Garlic; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy / Q000379:methods; D010938:Plant Oils / Q000302:isolation & purification / Q000627:therapeutic use*
chemical_list: D010938:Plant Oils