Catalytic enantioselective arylation of aldehydes: boronic acids as a suitable source of transferable aryl groups.
The catalytic enantioselective arylation of several aldehydes using boronic acids as the source of transferable aryl groups is described; the reaction is found to proceed in excellent yields and high enantioselectivities (up to 97% ee) in the presence of a chiral amino alcohol.
Braga
Antonio L
AL
Departamento de Quimica, Universidade Federal de Santa Maria, 97105-900, Santa Maria, RS, Brazil. albraga@quimica.ufsm.br
Lüdtke
Diogo S
DS
Vargas
Fabrício
F
Paixão
Marcio W
MW