The role of inflammation in acute coronary syndromes: review of the literature.
Extensive evidence supports a pathogenic role for both local and systemic inflammation in acute coronary syndrome (ACS). The determination of inflammatory markers levels in combination with the new imaging modalities can be used to identify patients at high risk of future cardiovascular events. Interestingly, this inflammatory component is a novel therapeutic target in ACS.
Elhajj
Ihab I
II
Departments of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon. ih02@aub.edu.lb
Haydar
Ali A
AA
Hujairi
Nabil M
NM
Goldsmith
David J
DJ
D000789:Angina, Unstable / Q000097:blood / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001161:Arteriosclerosis / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D001241:Aspirin / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis*; D015815:Cell Adhesion Molecules / Q000097:blood; D003327:Coronary Disease / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D003328:Coronary Thrombosis / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D007249:Inflammation / Q000503:physiopathology*; D009203:Myocardial Infarction / Q000097:blood / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D016032:Randomized Controlled Trials as Topic; D012008:Recurrence; D012307:Risk Factors; D013577:Syndrome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D015415:Biomarkers; D015815:Cell Adhesion Molecules; D000960:Hypolipidemic Agents; D010975:Platelet Aggregation Inhibitors; D002097:C-Reactive Protein; D001241:Aspirin