IV thrombolysis in patients with acute stroke due to spontaneous carotid dissection.
The authors reviewed the histories of 33 patients (ages 44 to 50 years) treated with IV thrombolysis for acute stroke due to spontaneous cervical carotid artery dissection. Median NIH Stroke Scale (NIHSS) score on admission was 15. No new or worsened local signs, subarachnoid hemorrhage, pseudoaneurysm formation, or rupture of the cervical ICA were observed. At 3 months, median NIHSS was 7 and median modified Rankin Scale (mRS) 2.5; mRS < or = 2 was observed in 17 patients.
Georgiadis
D
D
Department of Neurology, University of Zürich, Zürich, Switzerland. dimitrios.georgiadis@usz.ch
Lanczik
O
O
Schwab
S
S
Engelter
S
S
Sztajzel
R
R
Arnold
M
M
Siebler
M
M
Schwarz
S
S
Lyrer
P
P
Baumgartner
R W
RW
D000328:Adult; D020520:Brain Infarction / Q000139:chemically induced / Q000473:pathology / Q000503:physiopathology; D020215:Carotid Artery, Internal, Dissection / Q000150:complications* / Q000188:drug therapy* / Q000503:physiopathology; D020216:Carotid-Cavernous Sinus Fistula / Q000139:chemically induced / Q000473:pathology / Q000503:physiopathology; D002543:Cerebral Hemorrhage / Q000139:chemically induced / Q000473:pathology / Q000503:physiopathology; D003389:Cranial Nerve Diseases / Q000139:chemically induced / Q000473:pathology / Q000503:physiopathology; D005260:Female; D005343:Fibrinolytic Agents / Q000009:adverse effects*; D006732:Horner Syndrome / Q000139:chemically induced / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D020767:Intracranial Thrombosis / Q000139:chemically induced* / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D020521:Stroke / Q000139:chemically induced* / Q000473:pathology / Q000503:physiopathology; D013345:Subarachnoid Hemorrhage / Q000139:chemically induced* / Q000473:pathology / Q000503:physiopathology; D010959:Tissue Plasminogen Activator / Q000009:adverse effects / Q000627:therapeutic use
D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator