Analgesic activity of the roots and leaves extracts of Calliandra portoricensis.
The analgesic activity of the methanolic extracts of the roots and leaves of Calliandra portoricensis was investigated in mice and rats using acetic acid-induced writhing and formalin tests. The extracts given orally at the doses of 200, 400, 600 mg/kg showed a dose-dependent activity in the tests used.
Agunu
Abdulkarim
A
Department of Pharmacognosy and Drug Development, Ahmadu Bello University, Zaria, Nigeria. agunua@yahoo.com
Abdurahman
E M
EM
Shok
M
M
Yusuf
Sadiq A
SA
D019342:Acetic Acid; D000284:Administration, Oral; D000700:Analgesics / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D004305:Dose-Response Relationship, Drug; D007887:Fabaceae; D005557:Formaldehyde; D008297:Male; D051379:Mice; D010146:Pain / Q000139:chemically induced / Q000517:prevention & control*; D010147:Pain Measurement / Q000187:drug effects; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D018517:Plant Roots; D051381:Rats
D000700:Analgesics; D010936:Plant Extracts; D005557:Formaldehyde; D019342:Acetic Acid