title: Pre-pro-somatostatin-III may have cortistatin-like functions in fish.
abstract: This study analyzes daily changes in the expression of somatostatin precursors PSS-I and PSS-III (structurally related to cortistatin) in the goldfish brain. The results indicate that PSS-I expression correlates with the light cycle only in optic tectum-thalamus (OT-Tha). PSS-III expression correlates with the light cycle in telencephalon-preoptic area (Tel-POA) and OT-Tha. In Tel-POA, PSS-III reaches a minimum level at the beginning of the active phase and a maximum level late in this phase. These results suggest that PSS-I in OT-Tha and PSS-III in Tel-POA and OT-Tha could be involved in the control of the activity cycles in goldfish.
authors.affiliation: Department of Biological Sciences, University of Alberta, Edmonton, Canada.
authors.forename: Luis Fabián
authors.initials: LF
authors.lastname: Canosa
authors.forename: Richard Ector
authors.initials: RE
authors.lastname: Peter
mesh_terms: D000818:Animals; D002940:Circadian Rhythm / Q000235:genetics / Q000502:physiology; D006054:Goldfish / Q000235:genetics / Q000502:physiology*; D009479:Neuropeptides / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D011498:Protein Precursors / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D013004:Somatostatin / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D029961:Zebrafish Proteins / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology
chemical_list: D009479:Neuropeptides; D011498:Protein Precursors; D029961:Zebrafish Proteins; C504314:cort protein, zebrafish; C099323:cortistatin; D013004:Somatostatin; C028456:prosomatostatin