title: The effect of packaging materials on the stability of sunscreen emulsions.
abstract: The purpose of this research was to study the stability of a emulsion containing UVA, UVB and infrared sunscreens after storage in different types of packaging materials (glass and plastic flasks; plastic and metallic tubes). The samples, emulsions containing benzophenone-3 (B-3), octyl methoxycinnamate (OM) and Phycocorail, were stored at 10, 25, 35 and 45 degrees C and representative samples were analyzed after 2, 7, 30, 60 and 90 days period. The stability studies were conducted by analyzing samples at pre-determined intervals by high performance liquid chromatography (HPLC) along with periodic rheological measurements.
authors.affiliation: Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, Caixa Postal 66083, CEP 05315-970 São Paulo, SP, Brazil. ines@usp.br
authors.forename: Maria Inês R M
authors.initials: MI
authors.lastname: Santoro
authors.forename: Daniella Almança Gonçalves
authors.initials: DA
authors.lastname: Da Costa E Oliveira
authors.forename: Erika R M
authors.initials: ER
authors.lastname: Kedor-Hackmann
authors.forename: Anil K
authors.initials: AK
authors.lastname: Singh
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004349:Drug Packaging; D004355:Drug Stability; D004655:Emulsions; D007202:Indicators and Reagents; D012015:Reference Standards; D015203:Reproducibility of Results; D012212:Rheology; D012997:Solvents; D013056:Spectrophotometry, Ultraviolet; D013473:Sunscreening Agents / Q000737:chemistry*
chemical_list: D004655:Emulsions; D007202:Indicators and Reagents; D012997:Solvents; D013473:Sunscreening Agents