title: Peripheral glia: Schwann cells in motion.
abstract: Neuregulin signaling through ErbB receptors is known to play an essential role in Schwann cell proliferation, survival and myelination. Recent studies in zebrafish provide a peek at living Schwann cells migrating along axons in vivo and suggest that ErbB signaling, while not required for cell movement per se, is required to maintain the directed migration of these cells.
authors.affiliation: The Scripps Institute, La Jolla, CA 92037, USA. carylai@scripps.edu
authors.forename: Cary
authors.initials: C
authors.lastname: Lai
mesh_terms: D000818:Animals; D001369:Axons / Q000502:physiology*; D002465:Cell Movement / Q000502:physiology*; D049109:Cell Proliferation; D009154:Mutation / Q000235:genetics; D009186:Myelin Sheath / Q000378:metabolism*; D020880:Neuregulins / Q000378:metabolism*; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000235:genetics / Q000378:metabolism; D012583:Schwann Cells / Q000378:metabolism / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D015027:Zebrafish
chemical_list: D020880:Neuregulins; D018719:Erb-b2 Receptor Tyrosine Kinases