Pediatric epilepsy -- an Indian perspective.
Prevalence studies from India suggest that epilepsy prevalence is similar to developed nations. Neurocysticercosis (NCC) predominates as an etiology. A large treatment gap is still a public health problem. Benign epilepsies and West syndrome appear to be underrepresented in studies on classification of seizures/syndromes. Febrile seizures prevalence in India is similar to other countries and appear to be as benign. Risk factors of intractable epilepsy (IE) in Indian studies include early age of onset, neurodevelopmental abnormalities and certain seizure types. Perinatal injuries underlie many IE. Many IE are not truly intractable and respond to simple therapeutic measures. The ketogenic diet and surgery are other methods now being used in Indian centers. Neurocysticercosis and neonatal hypoglycemic brain injury, two widely prevalent etiologies are reviewed in detail.
Udani
Vrajesh
V
Grant Medical College & JJ Group of Hospitals, PD Hinduja National Hospital and BJ Wadia Hospital for Children, Mumbai, India. vrajesh@vsnl.com
D000367:Age Factors; D001720:Birth Injuries / Q000150:complications; D001930:Brain Injuries / Q000150:complications; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004032:Diet; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis / Q000178:diet therapy / Q000453:epidemiology / Q000209:etiology / Q000601:surgery / Q000628:therapy; D020936:Epilepsy, Benign Neonatal / Q000453:epidemiology; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000150:complications; D007194:India; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D020019:Neurocysticercosis / Q000150:complications; D012307:Risk Factors; D003294:Seizures, Febrile / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D012737:Sex Factors; D013036:Spasms, Infantile / Q000453:epidemiology