title: Inhibition of matrix metalloproteinase-9 by "multi-prong" surface binding groups.
abstract: A novel strategy of blocking the active site accessibility of MMP-9 by "multi-prong" surface binding groups is described.
authors.affiliation: Department of Chemistry, Biochemistry and Molecular Biology, North Dakota State University, Fargo, ND 58105, USA.
authors.forename: Abir L
authors.initials: AL
authors.lastname: Banerjee
authors.forename: Shakila
authors.initials: S
authors.lastname: Tobwala
authors.forename: Manas K
authors.initials: MK
authors.lastname: Haldar
authors.forename: Michael
authors.initials: M
authors.lastname: Swanson
authors.forename: Bidhan C
authors.initials: BC
authors.lastname: Roy
authors.forename: Sanku
authors.initials: S
authors.lastname: Mallik
authors.forename: D K
authors.initials: DK
authors.lastname: Srivastava
mesh_terms: D003300:Copper / Q000737:chemistry*; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D007098:Imino Acids / Q000737:chemistry*; D053506:Matrix Metalloproteinase 10; D020780:Matrix Metalloproteinase 9 / Q000737:chemistry; D061965:Matrix Metalloproteinase Inhibitors; D008666:Metalloendopeptidases / Q000037:antagonists & inhibitors / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D013499:Surface Properties
chemical_list: D004791:Enzyme Inhibitors; D007098:Imino Acids; D061965:Matrix Metalloproteinase Inhibitors; D009942:Organometallic Compounds; D003300:Copper; D008666:Metalloendopeptidases; D053506:Matrix Metalloproteinase 10; D020780:Matrix Metalloproteinase 9; C008109:iminodiacetic acid