title: [Necrotizing pneumonia due to Rhodococcus equi in non HIV immunocompromised host. Case report and review].
abstract: Rhodococcus equi, is a grampositive intracellular bacillus, that causes infection mainly in immunocompromised hosts. We report the case of a 52 years old woman, with a systemic lupus erythematosus and a progressive 10 months evolution with cough, dyspnea, mucous-purulent sputum, occasionally hemoptysis, intermittent fever, and weight loss of 10%. With partial response to antibiotic treatment, radiological evolution of thoracic scanners evidenced the development of multiple bilateral areas of consolidation, some of them nodular. Percutaneous thoracic biopsy showed characteristic histology and microbiological analysis yielded the identification of Rhodococcus equi in both bronchoalveolar lavage and pulmonary biopsy. She received prolonged bi-associated antibiotic treatment with good clinical and radiological response. This agent must be considered in the study of immunocompromised patients that present with a prolonged evolution of pneumonia.
authors.affiliation: Departamento de Medicina Interna, Escuela de Medicina, Pontificia Universidad Católica de Chile. rabagli@med.puc.cl
authors.forename: Ricardo
authors.initials: R
authors.lastname: Rabagliati
authors.forename: Arturo
authors.initials: A
authors.lastname: Morales
authors.forename: René
authors.initials: R
authors.lastname: Baudrand
authors.forename: Jorge
authors.initials: J
authors.lastname: Jorquera
authors.forename: David
authors.initials: D
authors.lastname: Oddó
authors.forename: Patricia
authors.initials: P
authors.lastname: García
authors.forename: M Cecilia
authors.initials: MC
authors.lastname: Carmona
authors.forename: Marcela
authors.initials: M
authors.lastname: Cisternas
authors.forename: Alvaro
authors.initials: A
authors.lastname: Huete
mesh_terms: D000193:Actinomycetales Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D016929:Rhodococcus equi / Q000302:isolation & purification*