Epidemiology and genetic characterization of HIV-1 isolates in the general population of Djibouti (Horn of Africa).
During a national survey in 2002 in Djibouti, serum samples were collected using a valid sampling scheme from 2423 Djiboutians representing the general population of urban and rural districts. The HIV-1 seroprevalence was 2%. The HIV-1 polymerase gene from 53 untreated patients was amplified. Phylogenetic analysis of 34 isolates revealed a majority of subtype C (73%) as well as other subtypes, including CRF02_AG recombinants (18%), subtype D (6%), and subtype A (3%).
Maslin
Jérôme
J
Laboratoire de Biologie Médicale, Hôpital d'Instruction des Armées du Val de Grâce, Paris, France. j.maslin@wanadoo.fr
Rogier
Christophe
C
Berger
Franck
F
Khamil
Mohamed Ali
MA
Mattera
Didier
D
Grandadam
Marc
M
Caron
Mélanie
M
Nicand
Elizabeth
E
D000368:Aged; D000369:Aged, 80 and over; D001921:Brain; D015730:Djibouti / Q000453:epidemiology; D016330:Frail Elderly; D015658:HIV Infections / Q000453:epidemiology*; D015528:HIV Seroprevalence; D015497:HIV-1 / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D019562:Viral Load