Nocardiosis in a teaching hospital in the Central Anatolia region of Turkey: treatment and outcome.
Predisposing factors, antimicrobial susceptibility patterns, treatment and outcome were analysed for nine consecutive patients with nocardiosis. Predisposing factors were identified in six (67%) of the nine patients. Clinical syndromes of nocardial infection were pulmonary infection (three patients), cerebral infection (five patients) and disseminated infection (one patient). The predominant (60%) species was Nocardia farcinica rather than the Nocardia asteroides complex. Treatment was started empirically, modified according to the antimicrobial susceptibility pattern, and then continued for 6-12 months. Overall mortality was 33%, with death being caused by the Nocardia infection in two cases.
Yildiz
O
O
Infectious Diseases, Medical Faculty, Erciyes University, Kayseri, Turkey. oyildiz@erciyes.edu.tr
Alp
E
E
Tokgoz
B
B
Tucer
B
B
Aygen
B
B
Sumerkan
B
B
Couble
A
A
Boiron
P
P
Doganay
M
M
D000328:Adult; D000583:Amikacin / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001922:Brain Abscess / Q000473:pathology / Q000601:surgery; D015984:Causality; D002443:Ceftriaxone / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D015378:Imipenem / Q000494:pharmacology; D008171:Lung Diseases / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008826:Microbial Sensitivity Tests; D009615:Nocardia / Q000187:drug effects / Q000302:isolation & purification*; D009617:Nocardia Infections / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D012189:Retrospective Studies; D014421:Turkey / Q000453:epidemiology
D000900:Anti-Bacterial Agents; D015378:Imipenem; D002443:Ceftriaxone; D000583:Amikacin