title: Structure of msj-1 gene: a comparative analysis.
abstract: Msj-1 gene encodes a DnaJ protein highly expressed in spermatids and spermatozoa of both rodents and amphibians. We isolated and characterized the msj-1 gene in mice. A bioinformatic approach was then used to predict the putative promoter region, chromosomal localization, and its presence in the human genome. The analysis of msj-1 genomic sequence revealed that msj-1 is an intronless gene. Interestingly, two regions (A and B, separated by 10,682 bp) on human chromosome 2 having respectively 78% and 77% nucleotide identity with the murine msj-1 coding region were identified. This suggests the existence of an msj-1-like gene also in humans.
authors.affiliation: Department of Experimental Medicine, Second University of Naples, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Meccariello
authors.forename: G
authors.initials: G
authors.lastname: Tedeschi
authors.forename: M R
authors.initials: MR
authors.lastname: Monsurrò
authors.forename: R
authors.initials: R
authors.lastname: Chianese
authors.forename: G
authors.initials: G
authors.lastname: Cobellis
authors.forename: R
authors.initials: R
authors.lastname: Pierantoni
authors.forename: S
authors.initials: S
authors.lastname: Fasano
mesh_terms: D000818:Animals; D050956:HSP40 Heat-Shock Proteins / Q000737:chemistry* / Q000235:genetics*; D051379:Mice; D011401:Promoter Regions, Genetic / Q000235:genetics
chemical_list: C494642:Dnajb3 protein, mouse; D050956:HSP40 Heat-Shock Proteins