Transepidermal water loss dynamics of human vulvar and thigh skin.
Refinement in procedures to assess skin surface water loss (SSWL) dynamics of the vulvar skin on a large sample of subjects (60) is described and compared to another semi-occluded skin site, the inner thigh. Vulvar SSWL significantly decreased over a 30-min period from 46.2 +/- 2.6 (SE) to 24.7 +/- 1.6 g m(-2) h (p < 0.001). The inner thigh, another semi-occluded region, showed no similar pattern for SSWL (6.2 +/- 0.3 to 6.6 +/- 0.5 g m(-2) h), and the values were significantly less than those for vulvar skin. There was no significant effect of age, body mass index or atopic status on vulvar SSWL.
Warren
R
R
Winton Hill Technical Center Feminine Care, Procter and Gamble Company, Cincinnati, OH 45224, USA. warren.r@pg.com
Bauer
A
A
Greif
C
C
Wigger-Alberti
W
W
Jones
M B
MB
Roddy
M T
MT
Seymour
J L
JL
Hansmann
M A
MA
Elsner
P
P
D000293:Adolescent; D000328:Adult; D000375:Aging / Q000502:physiology; D015992:Body Mass Index; D003020:Clothing; D004817:Epidermis / Q000502:physiology; D005260:Female; D006801:Humans; D012879:Skin Physiological Phenomena; D013848:Thigh; D014844:Vulva / Q000502:physiology*; D014870:Water Loss, Insensible / Q000502:physiology*