Clinical update on renal aquaporins.
Following the discovery of the aquaporin-1 water channel over a decade ago, molecular techniques have been developed to examine the role of renal aquaporin water channels under numerous physiological and pathological conditions. The present article reviews current knowledge regarding the function and dysfunction of renal aquaporins in disorders of water metabolism.
Chen
Yung-Chang
YC
Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA.
Cadnapaphornchai
Melissa A
MA
Schrier
Robert W
RW
D000818:Animals; D020346:Aquaporins / Q000378:metabolism / Q000502:physiology*; D005938:Glucocorticoids / Q000172:deficiency; D006801:Humans; D007037:Hypothyroidism / Q000473:pathology; D007668:Kidney / Q000378:metabolism*; D007674:Kidney Diseases / Q000473:pathology; D007685:Kidney Tubules, Collecting / Q000378:metabolism; D008901:Mineralocorticoids / Q000172:deficiency; D008954:Models, Biological
D020346:Aquaporins; D005938:Glucocorticoids; D008901:Mineralocorticoids