Quantitative evaluation of coronary arterial stenosis using 16-slice multidetector-row computed tomography: preliminary evaluation of phantom study.
OBJECTIVE
The purpose of this study is to consider the possibility of quantitative evaluation of coronary arterial stenosis by using 16-slice multidetector-row computed tomography (MDCT).


METHODS
Simulated coronary arteries were prepared, which consist of 5-mm-diameter acryl tubes with contrast media (270 HU). Simulated stenoses of known density (-33 HU) were created in each coronary artery (25%, 50%, and 75%). Cardiac pulsating with 0, 50, 65, 85, and 105 beats per minute (bpm) was performed. Multiplanar reformation images for each coronary artery were created. Percent stenosis was calculated using the width middle value of boundary part of the arteries.


RESULTS
The stenoses were depicted in all heart rates. Average percent stenosis +/- standard deviation was 27.4 +/- 3.6%, 45.8 +/- 2.6%, and 69.4 +/- 2.7%, respectively. For each percent stenosis, there was a significant difference (P < 0.05).


CONCLUSIONS
Sixteen-slice MDCT has a potential for noninvasive quantitative evaluation of stenosis in coronary arteries.
Yamada
Minoru
M
Cardiovascular Imaging Laboratory in Research Park, Keio University School of Medicine, Tokyo, Japan. yamada@mr.med.keio.ac.jp
Jinzaki
Masahiro
M
Kuribayashi
Sachio
S
Sato
Kozo
K
Tanami
Yutaka
Y
Yun
Shen
S
Sasaki
Kosuke
K
Okano
Yoshiyuki
Y
Sugisawa
Koichi
K
D023921:Coronary Stenosis / Q000000981:diagnostic imaging*; D019047:Phantoms, Imaging; D014057:Tomography, X-Ray Computed / Q000379:methods