title: Contrast-enhanced MR angiography for evaluation of vascular complications of the pancreatic transplant.
abstract: Vascular complications are a common cause of postoperative dysfunction in a pancreatic transplant. Coronal three-dimensional (3D) contrast material-enhanced magnetic resonance (MR) angiography performed with high spatial and temporal resolution is a safe and effective method of assessing these vascular complications. A study was performed of selected patients who had undergone MR imaging and MR angiography during the past 6 years for evaluation of graft dysfunction following pancreatic transplantation. Thrombosis within peripheral stump vessels involving either the arterial or venous segments was a commonly observed vascular complication. Isolated distal arterial stump thrombi are incidental findings that may not require treatment, whereas venous stump thrombi may become clinically significant in patients in whom clot propagates proximally to occlude draining pancreatic veins and are typically treated with anticoagulants or thrombectomy. Because it is difficult to predict which patients will experience clot propagation, patients with venous stump thrombi may be followed up with serial imaging regardless of treatment initiated at presentation. Although susceptibility artifacts can mimic anastomotic stenoses at MR imaging, careful attention to the multiple sequences used allows recognition of this potential pitfall. Contrast-enhanced 3D MR angiography is an accurate method of evaluating the vascular anatomy of pancreatic transplants and can help guide clinical management.
authors.affiliation: Department of Radiology, MRI Learning Center, 1 Founders, Hospital of the University of Pennsylvania, Philadelphia, USA. dobosn@att.net
authors.forename: Nora
authors.initials: N
authors.lastname: Dobos
authors.forename: David A
authors.initials: DA
authors.lastname: Roberts
authors.forename: Erik K
authors.initials: EK
authors.lastname: Insko
authors.forename: Evan S
authors.initials: ES
authors.lastname: Siegelman
authors.forename: Ali
authors.initials: A
authors.lastname: Naji
authors.forename: James F
authors.initials: JF
authors.lastname: Markmann
mesh_terms: D003287:Contrast Media; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D016035:Pancreas Transplantation / Q000009:adverse effects*; D011859:Radiography; D014652:Vascular Diseases / Q000000981:diagnostic imaging* / Q000209:etiology*
chemical_list: D003287:Contrast Media