Implicit associative learning engages the hippocampus and interacts with explicit associative learning.
The hippocampus is crucial for conscious, explicit memory, but whether it is also involved in nonconscious, implicit memory is uncertain. We investigated with functional magnetic resonance imaging whether implicit learning engages the hippocampus and interacts with subsequent explicit learning. The presentation of subliminal faces-written profession pairs for implicit learning was followed by the explicit learning of supraliminal pairs composed of the same faces combined with written professions semantically incongruous to those presented subliminally (experiment 1), semantically congruous professions (experiment 2), or identical professions (experiment 3). We found that implicit face-profession learning interacted with explicit face-profession learning in all experiments, impairing the explicit retrieval of the associations. Hippocampal activity increased during the subliminal presentation of face-profession pairs versus face-nonword pairs and correlated with the later impairment of explicit retrieval. These findings suggest that implicit semantic associative learning engages the hippocampus and influences explicit memory.
Degonda
Nadia
N
Division of Psychiatry Research, University of Zurich, Switzerland.
Mondadori
Christian R A
CR
Bosshardt
Simone
S
Schmidt
Conny F
CF
Boesiger
Peter
P
Nitsch
Roger M
RM
Hock
Christoph
C
Henke
Katharina
K
D001245:Association Learning / Q000502:physiology*; D001931:Brain Mapping; D006624:Hippocampus / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D008568:Memory / Q000502:physiology*; D010775:Photic Stimulation; D013360:Subliminal Stimulation; D014796:Visual Perception