Molecular mechanisms of epigenetics.
The main epigenetic mechanisms in regulation of gene expression are discussed. The definition of epigenetics and its specific mechanisms including DNA methylation and gene imprinting, modifications of nucleosomal histones associated with silencing or activation of gene transcription, RNA interference, chromosomal silencing, and the role of mobile elements are discussed.
Tchurikov
N A
NA
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia. tchurikov@eimb.ru
D000107:Acetylation; D000818:Animals; D019175:DNA Methylation; D044127:Epigenesis, Genetic; D018392:Genomic Imprinting; D006570:Heterochromatin / Q000378:metabolism*; D006657:Histones / Q000378:metabolism*; D006801:Humans; D020071:Interspersed Repetitive Sequences; D034622:RNA Interference
D006570:Heterochromatin; D006657:Histones