Concentrated hydroxyapatite inks for direct-write assembly of 3-D periodic scaffolds.
Hydroxyapatite (HA) scaffolds with a 3-D periodic architecture and multiscale porosity have been fabricated by direct-write assembly. Concentrated HA inks with tailored viscoelastic properties were developed to enable the construction of complex 3-D architectures comprised of self-supporting cylindrical rods in a layer-by-layer patterning sequence. By controlling their lattice constant and sintering conditions, 3-D periodic HA scaffolds were produced with a bimodal pore size distribution. Mercury intrusion porosimetry (MIP) was used to determine the characteristic pore size and volume associated with the interconnected pore channels between HA rods and the finer pores within the partially sintered HA rods.
Michna
Sarah
S
Materials Science and Engineering Department, University of Illinois, Urbana, IL 61801, USA.
Wu
Willie
W
Lewis
Jennifer A
JA
D001672:Biocompatible Materials / Q000737:chemistry; D018786:Bone Substitutes / Q000032:analysis / Q000737:chemistry*; D018929:Cell Culture Techniques / Q000379:methods; D003460:Crystallization / Q000379:methods*; D004548:Elasticity; D005109:Extracellular Matrix / Q000737:chemistry*; D006882:Hydroxyapatites / Q000737:chemistry*; D007281:Ink; D008422:Materials Testing; D044085:Microfluidics / Q000379:methods*; D010316:Particle Size; D016062:Porosity; D013048:Specimen Handling / Q000379:methods; D013499:Surface Properties; D023822:Tissue Engineering / Q000379:methods*; D014783:Viscosity
D001672:Biocompatible Materials; D018786:Bone Substitutes; D006882:Hydroxyapatites