title: The past is the future: innovative designs in acute stroke therapy trials.
authors.affiliation: Pfizer Global Research and Development, Groton, Conn, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Krams
authors.forename: Kennedy R
authors.initials: KR
authors.lastname: Lees
authors.forename: Donald A
authors.initials: DA
authors.lastname: Berry
mesh_terms: D001499:Bayes Theorem; D002986:Clinical Trials as Topic / Q000379:methods* / Q000639:trends*; D006801:Humans; D015233:Models, Statistical; D008962:Models, Theoretical; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D012107:Research Design; D018401:Sample Size; D020521:Stroke / Q000628:therapy*
chemical_list: D018696:Neuroprotective Agents