Infestivity of Demodex canis to hamster skin engrafted onto SCID mice.
We demonstrated that Demodex canis was transferred to skin xenografts of a dog and a hamster onto severe combined immunodeficiency mice. After the transfer of mites, the number of eggs, larvae, nymphs and adult mites per gram of canine and hamster xenografts increased, whereas no live mites were detected on murine allograft. These results indicate that D. canis proliferates in hair follicles of dog and hamster skins but not in murine allograft. Therefore, D. canis may have host preference but not strict host-specificity.
Tani
Kenji
K
Department of Veterinary Surgery, Faculty of Agriculture, Yamaguchi University, Japan.
Une
Satoshi
S
Hasegawa
Atsuhiko
A
Adachi
Makoto
M
Kanda
Naoko
N
Watanabe
Shin-ichi
S
Nakaichi
Munekazu
M
Taura
Yasuho
Y
D000818:Animals; D006224:Cricetinae; D004285:Dogs; D006652:Histological Techniques; D051379:Mice; D016513:Mice, SCID; D008924:Mite Infestations / Q000473:pathology*; D008925:Mites / Q000254:growth & development / Q000502:physiology*; D016038:Skin Transplantation; D013045:Species Specificity; D014183:Transplantation, Heterologous