title: Carcinosarcoma of the prostate with multiple metastases: case report and review of the literature.
abstract: A case of carcinosarcoma of the prostate in a previously healthy 65-year-old man is reported. The tumor was initially diagnosed as adenocarcinoma, but the prostatectomy specimen showed a 717-g prostate, with evidence of adenocarcinoma and carcinosarcoma without heterologous structures. By 3-month follow-up, local recurrence, and liver, lung, and bone metastases had developed in the patient. He died of disease 10 months postoperatively. Carcinosarcoma of the prostate is a very rare but highly aggressive cancer with limited therapeutic options that should be treated with surgery and managed symptomatically. We believe this article is the forty-second case reported in the literature.
authors.affiliation: Scott Department of Urology, Baylor College of Medicine, Houston, TX 77030, USA.
authors.forename: Vairavan S
authors.initials: VS
authors.lastname: Subramanian
authors.forename: Michael
authors.initials: M
authors.lastname: Coburn
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Miles
mesh_terms: D000368:Aged; D002296:Carcinosarcoma / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D011471:Prostatic Neoplasms / Q000473:pathology*