title: Expression of proopiomelanocortin and its cleavage enzyme genes in Rana esculenta and Xenopus laevis gonads.
abstract: Proopiomelanocortin (POMC) is the precursor protein of different hormones and neuropeptides, and the POMC-derived peptides are produced through proteolytic cleavage. Prohormone convertase PC1 and PC2 are enzymes responsible for the cleavage of the POMC prohormone. The coexpression of POMC, PC1, and PC2 genes was previously described in the brain and the pituitary gland of Rana esculenta and Xenopus laevis, but no data are available for the gonad. The present work demonstrates a gonadal POMC convertase gene expression in Rana esculenta and Xenopus laevis.
authors.affiliation: Dipartimento di Scienze Morfologiche e Biochimiche Comparate, Università di Camerino, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Carotti
authors.forename: M
authors.initials: M
authors.lastname: Nabissi
authors.forename: G
authors.initials: G
authors.lastname: Mosconi
authors.forename: F
authors.initials: F
authors.lastname: Gangnon
authors.forename: I
authors.initials: I
authors.lastname: Lihrmann
authors.forename: H
authors.initials: H
authors.lastname: Vaudry
authors.forename: A M
authors.initials: AM
authors.lastname: Polzonetti-Magni
mesh_terms: D000818:Animals; D005260:Female; D006066:Gonads / Q000378:metabolism; D008297:Male; D010053:Ovary / Q000378:metabolism*; D011333:Pro-Opiomelanocortin / Q000096:biosynthesis* / Q000235:genetics; D045664:Proprotein Convertase 1 / Q000096:biosynthesis / Q000235:genetics*; D045706:Proprotein Convertase 2 / Q000096:biosynthesis / Q000235:genetics*; D011893:Rana esculenta / Q000235:genetics / Q000378:metabolism*; D013737:Testis / Q000378:metabolism*; D014982:Xenopus laevis / Q000235:genetics / Q000378:metabolism*
chemical_list: D011333:Pro-Opiomelanocortin; D045664:Proprotein Convertase 1; D045706:Proprotein Convertase 2