title: Multifocal bone marrow involvement in cat-scratch disease.
abstract: We describe 2 children with prolonged fever of unknown origin and prominent skeletal pain who had multifocal bone disease caused by Bartonella infection. Initial radiologic studies, including plain films, radionuclide scintigraphy and computed tomography, yielded negative results. In both cases, magnetic resonance imaging revealed multiple enhancing bone marrow lesions consistent with clinical symptoms. Microbiologic diagnoses were established serologically.
authors.affiliation: Departments of Pediatrics, University of North Carolina, Chapel Hill, NC 27599-7593, USA. shipp@unch.unc.edu
authors.forename: Sean J
authors.initials: SJ
authors.lastname: Hipp
authors.forename: Ashley
authors.initials: A
authors.lastname: O'Shields
authors.forename: Lynn A
authors.initials: LA
authors.lastname: Fordham
authors.forename: Julie
authors.initials: J
authors.lastname: Blatt
authors.forename: Harvey J
authors.initials: HJ
authors.lastname: Hamrick
authors.forename: Frederick W
authors.initials: FW
authors.lastname: Henderson
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D018416:Bartonella henselae / Q000302:isolation & purification*; D001853:Bone Marrow / Q000382:microbiology / Q000473:pathology*; D002372:Cat-Scratch Disease / Q000150:complications / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D010019:Osteomyelitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D018570:Risk Assessment; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents