title: Carotid artery resection: preoperative temporary occlusion is not always an accurate predictor of collateral blood flow.
abstract: CONCLUSIONS
  The morbidity predicted by means of preoperative PET studies does not always correlate with the morbidity experienced after permanent carotid artery occlusion. A pre-resection extracranial-intracranial bypass may be necessary to reduce the risk of neurologic morbidity, in particular when carotid artery resection is planned for tumors involving the skull base.
  
  
  OBJECTIVE
  Carotid artery resection is generally considered the only curative treatment for patients with advanced head and neck carcinoma involving the carotid artery. PET can be used during temporary occlusion of the internal carotid artery to assess the safety of the procedure. The aims of this paper were to clarify the risk of carotid artery resection and the benefit of extracranial-intracranial bypass.
  
  
  METHODS
  Twelve patients diagnosed with head and neck cancer adherent to the carotid artery and in proximity to the skull base who had shown good hemispheric collateral blood flow by means of PET underwent carotid artery resection without preoperative bypass.
  
  
  RESULTS
  Of the 12 patients who underwent carotid artery resection without reconstruction, 10 suffered no serious neurologic complications; however, 2 suffered cerebral infarctions intraoperatively.
authors.affiliation: Department of Otolaryngology, Graduate School of Medicine, Chiba University, Chiba, Japan.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Chazono
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Okamoto
authors.forename: Zensei
authors.initials: Z
authors.lastname: Matsuzaki
authors.forename: Shigetoshi
authors.initials: S
authors.lastname: Horiguchi
authors.forename: Tomokazu
authors.initials: T
authors.lastname: Matsuoka
authors.forename: Tooru
authors.initials: T
authors.lastname: Horikoshi
authors.forename: Hideaki
authors.initials: H
authors.lastname: Nukui
authors.forename: Hiromu
authors.initials: H
authors.lastname: Hadeishi
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Yasui
mesh_terms: D000230:Adenocarcinoma / Q000098:blood supply / Q000473:pathology / Q000601:surgery; D000328:Adult; D000368:Aged; D021721:Balloon Occlusion / Q000295:instrumentation; D002294:Carcinoma, Squamous Cell / Q000098:blood supply / Q000473:pathology / Q000601:surgery; D002343:Carotid Artery, Internal / Q000473:pathology* / Q000601:surgery*; D002548:Cerebral Revascularization / Q000379:methods; D003097:Collateral Circulation / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008443:Maxillary Sinus / Q000098:blood supply / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D010255:Paranasal Sinus Neoplasms / Q000098:blood supply / Q000473:pathology / Q000601:surgery; D010307:Parotid Neoplasms / Q000098:blood supply / Q000473:pathology / Q000601:surgery; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D011300:Preoperative Care; D018570:Risk Assessment; D019043:Vascular Neoplasms / Q000098:blood supply / Q000473:pathology / Q000601:surgery