[Visualization of regenerated sciatic nerve of rat after injury].
There is close relationship between the morphologic changes of peripheral nerve after injury and its function recovery during regeneration. In our experiment, the sciatic nerve of rats was transected and bridge-connected with silicone tube, and the images of serial slices of different time and different injury parts were taken by micro-photograph system. The volume unit model was applied to rendering the three dimensional (3D) structure of degenerative and regenerative sciatic nerve fiber and its affiliated structure after injury. The 3D images showed that node of Ranvier had not formed and its array was turbulent, both the myelin sheath and the axis-cylinder were thinner, and the collagen fibres had proliferated.
Chen
Jing
J
Bioengineering Institute, Chongqing University, Chongqing 400044, China.
Peng
Chenglin
C
Chu
Yanfei
Y
Zhu
Gang
G
Li
Bingcang
B
Zhao
Hui
H
Chen
Zhiqiang
Z
D000818:Animals; D008297:Male; D009416:Nerve Regeneration / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D020127:Recovery of Function; D012584:Sciatic Nerve / Q000293:injuries* / Q000473:pathology* / Q000503:physiopathology