title: Analytical solutions of electric potential and impedance for a multilayered spherical volume conductor excited by time-harmonic electric current source: application in brain EIT.
abstract: A model of a multilayered spherical volume conductor with four electrodes is built. In this model, a time-harmonic electric current is injected into the sphere through a pair of drive electrodes, and electric potential is measured by the other pair of measurement electrodes. By solving the boundary value problem of the electromagnetic field, the analytical solutions of electric potential and impedance in the whole conduction region are derived. The theoretical values of electric potential on the surface of the sphere are in good accordance with the experimental results. The analytical solutions are then applied to the simulation of the forward problem of brain electrical impedance tomography (EIT). The results show that, for a real human head, the imaginary part of the electric potential is not small enough to be ignored at above 20 kHz, and there exists an approximate linear relationship between the real and imaginary parts of the electric potential when the electromagnetic parameters of the innermost layer keep unchanged. Increase in the conductivity of the innermost layer leads to a decrease of the magnitude of both real and imaginary parts of the electric potential on the scalp. However, the increase of permittivity makes the magnitude of the imaginary part of the electric potential increase while that of the real part decreases, and vice versa.
authors.affiliation: School of Automation and Electrical Engineering, Beihang University, Beijing 100083, People's Republic of China. xiao_chunyan@163.com
authors.forename: Chunyan
authors.initials: C
authors.lastname: Xiao
authors.forename: Yinzhao
authors.initials: Y
authors.lastname: Lei
mesh_terms: D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology* / Q000502:physiology; D003198:Computer Simulation; D004553:Electric Conductivity; D017097:Electric Impedance; D004566:Electrodes; D055590:Electromagnetic Phenomena; D006801:Humans; D008962:Models, Theoretical; D014054:Tomography / Q000379:methods*