title: Transepidermal water loss dynamics of human vulvar and thigh skin.
abstract: Refinement in procedures to assess skin surface water loss (SSWL) dynamics of the vulvar skin on a large sample of subjects (60) is described and compared to another semi-occluded skin site, the inner thigh. Vulvar SSWL significantly decreased over a 30-min period from 46.2 +/- 2.6 (SE) to 24.7 +/- 1.6 g m(-2) h (p < 0.001). The inner thigh, another semi-occluded region, showed no similar pattern for SSWL (6.2 +/- 0.3 to 6.6 +/- 0.5 g m(-2) h), and the values were significantly less than those for vulvar skin. There was no significant effect of age, body mass index or atopic status on vulvar SSWL.
authors.affiliation: Winton Hill Technical Center Feminine Care, Procter and Gamble Company, Cincinnati, OH 45224, USA. warren.r@pg.com
authors.forename: R
authors.initials: R
authors.lastname: Warren
authors.forename: A
authors.initials: A
authors.lastname: Bauer
authors.forename: C
authors.initials: C
authors.lastname: Greif
authors.forename: W
authors.initials: W
authors.lastname: Wigger-Alberti
authors.forename: M B
authors.initials: MB
authors.lastname: Jones
authors.forename: M T
authors.initials: MT
authors.lastname: Roddy
authors.forename: J L
authors.initials: JL
authors.lastname: Seymour
authors.forename: M A
authors.initials: MA
authors.lastname: Hansmann
authors.forename: P
authors.initials: P
authors.lastname: Elsner
mesh_terms: D000293:Adolescent; D000328:Adult; D000375:Aging / Q000502:physiology; D015992:Body Mass Index; D003020:Clothing; D004817:Epidermis / Q000502:physiology; D005260:Female; D006801:Humans; D012879:Skin Physiological Phenomena; D013848:Thigh; D014844:Vulva / Q000502:physiology*; D014870:Water Loss, Insensible / Q000502:physiology*