title: Cre-ating somatic cell genetic mosaics in the mouse.
abstract: Generation of somatic mosaics in which mutant cell clones are uniquely and completely labeled has yielded considerable insight into many biological processes in Drosophila. In this issue of Cell, describe a novel method called MADM that allows the generation of such mosaics in mice.
authors.forename: Todd E
authors.initials: TE
authors.lastname: Anthony
authors.forename: Nathaniel
authors.initials: N
authors.lastname: Heintz
mesh_terms: D000818:Animals; D019070:Cell Lineage / Q000235:genetics; D004330:Drosophila / Q000235:genetics; D005819:Genetic Markers; D005821:Genetic Techniques; D049452:Green Fluorescent Proteins / Q000235:genetics; D019426:Integrases / Q000235:genetics*; D008164:Luminescent Proteins / Q000235:genetics; D051379:Mice; D008938:Mitosis / Q000235:genetics; D009030:Mosaicism; D016254:Mutagenesis, Insertional / Q000235:genetics / Q000379:methods; D009154:Mutation / Q000235:genetics; D011995:Recombination, Genetic / Q000235:genetics*; D000097573:Red Fluorescent Protein
chemical_list: D005819:Genetic Markers; D049452:Green Fluorescent Proteins; D019426:Integrases; D008164:Luminescent Proteins; D000097573:Red Fluorescent Protein; C045073:Cre recombinase