title: Skin analysis to determine causative agent in dermal exposure to petroleum products.
abstract: This study evaluates the usefulness of skin analysis to determine the causative agent in cases of dermal exposure. The study consists of an animal experiment and two human cases. The petroleum components detected at high concentrations in skin samples resembled the composition of those in the corresponding petroleum products. However, the petroleum components in blood were detected at low concentrations and were a different composition. Skin is considered to be an advantageous sample to estimate the petroleum product in clinical and forensic cases of dermal exposure.
authors.affiliation: Department of Legal Medicine, Shimane University School of Medicine, 89-1 Enya, Izumo, Shimane 693-8501, Japan. yhieda@med.shimane-u.ac.jp
authors.forename: Yoko
authors.initials: Y
authors.lastname: Hieda
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Tsujino
authors.forename: Haruo
authors.initials: H
authors.lastname: Takeshita
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D001555:Benzene Derivatives / Q000032:analysis; D003872:Dermatitis / Q000097:blood / Q000175:diagnosis / Q000209:etiology; D017809:Fatal Outcome; D005260:Female; D005554:Forensic Medicine / Q000379:methods; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D005742:Gasoline / Q000633:toxicity; D006801:Humans; D006839:Hydrocarbons, Acyclic / Q000032:analysis; D007648:Kerosene / Q000506:poisoning / Q000633:toxicity; D008297:Male; D009281:Naphthalenes / Q000032:analysis; D010578:Petroleum / Q000506:poisoning*; D051381:Rats; D017207:Rats, Sprague-Dawley; D015203:Reproducibility of Results; D012867:Skin / Q000737:chemistry / Q000187:drug effects* / Q000473:pathology; D012871:Skin Diseases / Q000097:blood / Q000209:etiology
chemical_list: D001555:Benzene Derivatives; D005742:Gasoline; D006839:Hydrocarbons, Acyclic; D007648:Kerosene; D009281:Naphthalenes; D010578:Petroleum; C031721:naphthalene