title: Antimicrobial prophylaxis in allogeneic bone marrow transplantation. Guidelines of the infectious diseases working party (AGIHO) of the german society of haematology and oncology.
abstract: Patients undergoing allogeneic stem cell transplantation are at high risk for infection with a variety of pathogens during different phases of the procedure. Bacteria and fungi predominate the first phase until engraftment. During the second phase, from engraftment to about day 100, major infectious problems are caused by fungi and cytomegalovirus. Both pathogens remain important under continued immunosuppression, however, in the late post-transplantation period infections with encapsulated bacteria may become a problem. In this review the Infectious Diseases Working Party of the DGHO gives recommendations for prophylaxis of infections under allogeneic stem cell transplantation with drugs and other measures. The aim of the group was to do this on an evidence-based-medicine rating, if possible.
authors.affiliation: Medizinische Klinik C, Greifswald, Germany. william.krueger@uni-greifswald.de
authors.forename: W H
authors.initials: WH
authors.lastname: Krüger
authors.forename: J
authors.initials: J
authors.lastname: Bohlius
authors.forename: O A
authors.initials: OA
authors.lastname: Cornely
authors.forename: H
authors.initials: H
authors.lastname: Einsele
authors.forename: H
authors.initials: H
authors.lastname: Hebart
authors.forename: G
authors.initials: G
authors.lastname: Massenkeil
authors.forename: S
authors.initials: S
authors.lastname: Schüttrumpf
authors.forename: G
authors.initials: G
authors.lastname: Silling
authors.forename: A J
authors.initials: AJ
authors.lastname: Ullmann
authors.forename: D T
authors.initials: DT
authors.lastname: Waldschmidt
authors.forename: H-H
authors.initials: HH
authors.lastname: Wolf
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D016026:Bone Marrow Transplantation; D006801:Humans; D017053:Infection Control / Q000379:methods*; D011315:Preventive Medicine; D014184:Transplantation, Homologous
chemical_list: D000890:Anti-Infective Agents