title: Simultaneous chronic pulmonary paracoccidiodomycosis and disseminated cryptococcosis in a non-HIV patient.
abstract: An unusual case of chronic pulmonary paracoccidiodomycosis and disseminated cryptococcosis in a non-HIV infected patient is reported in a 72-year-old previously healthy man. A chest radiograph disclosed a bilateral diffused interstitial infiltrate involving middle and lower lung fields. Specimen samples taken from the tracheal tube revealed yeast-like organisms suggestive of Cryptococcus neoformans and Paracoccidiodes brasiliensis. Blood and cerebrospinal fluid culture was positive for C. neoformans and the immunodiffusion test against paracoccidiodin revealed a precipitation band. The patient died 24 days after the admission.
authors.affiliation: Pulmonary Disease Service, University Hospital of Santa Maria, Santa Maria, RS, Brazil. jwasb@yahoo.com
authors.forename: José Wellington Alves Dos
authors.initials: JW
authors.lastname: Santos
authors.forename: Maurício Licks da
authors.initials: ML
authors.lastname: Silveira
authors.forename: Fábio Pires
authors.initials: FP
authors.lastname: Santos
authors.forename: Aline Costa
authors.initials: AC
authors.lastname: Mathias
authors.forename: Alessandra Naimaier
authors.initials: AN
authors.lastname: Bertolazi
authors.forename: Carlos Renato Almeida
authors.initials: CR
authors.lastname: Melo
authors.forename: Loiva Ottonelli de
authors.initials: LO
authors.lastname: Oliveira
authors.forename: Luiz Carlos
authors.initials: LC
authors.lastname: Severo
authors.forename: Flávio de Mattos
authors.initials: Fde M
authors.lastname: Oliveira
mesh_terms: D000368:Aged; D002908:Chronic Disease; D003453:Cryptococcosis / Q000150:complications* / Q000000981:diagnostic imaging; D003455:Cryptococcus neoformans / Q000302:isolation & purification*; D017809:Fatal Outcome; D016469:Fungemia; D018023:HIV Seronegativity; D006801:Humans; D008172:Lung Diseases, Fungal / Q000134:cerebrospinal fluid / Q000000981:diagnostic imaging / Q000382:microbiology*; D008297:Male; D010228:Paracoccidioides / Q000302:isolation & purification*; D010229:Paracoccidioidomycosis / Q000150:complications* / Q000000981:diagnostic imaging; D013183:Sputum / Q000382:microbiology; D014057:Tomography, X-Ray Computed; D014132:Trachea / Q000382:microbiology