title: [High-dose buprenorphine substitution during incarceration. Management of opiate addicts].
abstract: OBJECTIVE
  To describe the social and medical profiles of incarcerated (in detention or after sentencing) opiate addicts, whether or not they had already begun substitution treatment at arrival, and assess the impact of high-dose buprenorphine substitution therapy on the health of prisoners and the course of their incarceration.
  
  
  METHODS
  A prospective survey was conducted on opiate addicts on admission to prison and after 2 months of incarceration, from December 2001 to February 2003, in 6 prison centres in the South East of France.
  
  
  RESULTS
  During incarceration, no significant difference (other than in medical follow-up) appeared between the prisoners receiving substitution treatment and those who went through withdrawal on arrival. The first group differed from the second in several respects: their occupational history before incarceration was less stable, their history of drug addiction and incarceration was more serious (injection, psychotropic use, number of prior incarcerations, early age at first incarceration). The buprenorphine patients also differed in their more intense use of medical follow-up before incarceration.
  
  
  CONCLUSIONS
  The impact of buprenorphine substitution therapy during incarceration could not be demonstrated, but prisoners receiving this treatment had a substantially different profile than those who were not receiving treatment when they arrived in prison.
authors.affiliation: Groupe de recherche sur la vulnérabilité sociale, Tourrette-Levens. catherine.reynaud@libertysurf.fr
authors.forename: Catherine
authors.initials: C
authors.lastname: Revnaud-Maurupt
authors.forename: Yves
authors.initials: Y
authors.lastname: Caer
authors.forename: Noëlle
authors.initials: N
authors.lastname: Escaffre
authors.forename: Murielle
authors.initials: M
authors.lastname: Gagneau
authors.forename: Anne
authors.initials: A
authors.lastname: Galinier
authors.forename: Jean-Noël
authors.initials: JN
authors.lastname: Marzo
authors.forename: Fadi
authors.initials: F
authors.lastname: Meroueh
mesh_terms: D000328:Adult; D000367:Age Factors; D002047:Buprenorphine / Q000008:administration & dosage / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005602:France; D019538:Health Care Surveys; D006801:Humans; D008297:Male; D009293:Opioid-Related Disorders / Q000188:drug therapy*; D011329:Prisoners; D011446:Prospective Studies; D013375:Substance Withdrawal Syndrome; D016896:Treatment Outcome
chemical_list: D002047:Buprenorphine