title: Occurrence and regional distribution of SHV-type extended-spectrum beta-lactamases in Hungary.
abstract: In order to determine the presence and geographical distribution of SHV-type extended-spectrum beta-lactamase genes among Enterobacteriaceae strains in Hungary, isolates from 25 microbiology laboratories throughout the country were collected between January 2002 and August 2003 and examined. Sequencing of the genes showed that SHV-5 and SHV-2a are the dominant SHV-types in extended-spectrum beta-lactamase-producing Enterobacteriaceae strains in this country. The SHV-2 gene, which is prevalent in many European countries, was not detected, but one isolate carried the SHV-12 gene. The results show that these genes are circulating among Enterobacteriaceae strains in Hungary and indicate that strict infection control measures are warranted in order to prevent their spread.
authors.affiliation: Department of Bacteriology, National Center for Epidemiology, Gyáli út 2-6, 1097 Budapest, Hungary. tothakos@oek.antsz.hu
authors.forename: A
authors.initials: A
authors.lastname: Tóth
authors.forename: M
authors.initials: M
authors.lastname: Gacs
authors.forename: K
authors.initials: K
authors.lastname: Márialigeti
authors.forename: G
authors.initials: G
authors.lastname: Cech
authors.forename: M
authors.initials: M
authors.lastname: Füzi
mesh_terms: D003428:Cross Infection / Q000382:microbiology; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000235:genetics; D004756:Enterobacteriaceae Infections / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D001618:beta-Lactamases