[Differential diagnosis of specific and nonspecific lung diseases by the parameters of the leukocytic enzymatic system].
The study examined 56 patients who were divided into three groups: 1) patients with infiltrative pulmonary tuberculosis; 2) those with nonspecific pneumonia; 3) control (apparently healthy individuals). In addition to the routine studies, the R. P. Nartsissov procedure was used to determine the activity of SDH and alpha-GPDH in all the examinees. The findings indicate that the lymphocytic activity of basic energy processes is much decreased in infiltrative tuberculosis and nonspecific pneumonia. Of the greatest value for active diagnosis is the determination of alpha-GPDH activity that is reduced only in patients with infiltrative pulmonary tuberculosis, its low activity points to profound redox disorders.
Chernyshov
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D000328:Adult; D015415:Biomarkers / Q000097:blood; D003937:Diagnosis, Differential; D005993:Glycerolphosphate Dehydrogenase / Q000097:blood*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000097:blood / Q000175:diagnosis*; D008214:Lymphocytes / Q000201:enzymology*; D013385:Succinate Dehydrogenase / Q000097:blood*; D014397:Tuberculosis, Pulmonary / Q000097:blood / Q000175:diagnosis*
D015415:Biomarkers; D005993:Glycerolphosphate Dehydrogenase; D013385:Succinate Dehydrogenase