title: NIV treatment for acute exacerbation in COPD patients.
abstract: The authors review the clinical applications of non invasive ventilation (NIV) in patients with chronic obstructive pulmonary disease (COPD), mostly focusing on NIV issues and possible solutions. After briefly reviewing the respiratory mechanics modification during an episode of COPD exacerbation, the authors describe the two crucial technical aspects (choice of the interface and leaks control) that are mostly involved in patient-ventilator interaction. Finally, they briefly review the most important clinical trials on NIV.
authors.affiliation: Department of Anesthesia and Resuscitation Sacro Cuore Catholic University, Rome, Italy. g.conti@rm.unicatt.it
authors.forename: G
authors.initials: G
authors.lastname: Conti
authors.forename: R
authors.initials: R
authors.lastname: Costa
authors.forename: A
authors.initials: A
authors.lastname: Craba
authors.forename: C
authors.initials: C
authors.lastname: Tafani
authors.forename: D
authors.initials: D
authors.lastname: Iemma
authors.forename: A
authors.initials: A
authors.lastname: Pellegrini
authors.forename: A
authors.initials: A
authors.lastname: Morelli
mesh_terms: D000328:Adult; D002986:Clinical Trials as Topic; D006801:Humans; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology / Q000628:therapy*; D012121:Respiration, Artificial / Q000295:instrumentation; D015656:Respiratory Mechanics / Q000502:physiology