title: [Experiences with intraoperative application of prednisolone during Isshiki type I thyroplasty].
abstract: Laryngeal edema is considered a postoperative problem in phonosurgery. In a prospective study we examined if a single intraoperative application of prednisolone can decrease the incidence of postoperative laryngeal edema after Isshiki type I thyroplasty. We examined ten patients undergoing unilateral type I thyroplasty [seven men and three women, age range: 19-60 years (average: 48 years)]. In six patients we administered 250 mg prednisolone i.v. during surgery. In four patients no steroids were given at all. On the 1st and 2nd postoperative day, the larynx was examined in a clinical setting. Five of six patients who received intraoperative steroid medication had no postoperative laryngeal edema. Only in one of those patients we examined a small edema of the arytenoid region. In all four patients without steroid medication a postoperative edema of the ipsilateral arytenoid hump was seen. Thus, intraoperative intravenous steroid administration seems to prevent, or at least reduce, postoperative laryngeal edema. Only in one of those patients we examined a small edema of the arytenoid region.
authors.affiliation: Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg. c.kothe@uke.uni-hamburg.de
authors.forename: C
authors.initials: C
authors.lastname: Kothe
authors.forename: G
authors.initials: G
authors.lastname: Schade
authors.forename: S
authors.initials: S
authors.lastname: Fleischer
authors.forename: T
authors.initials: T
authors.lastname: Grundmann
authors.forename: M
authors.initials: M
authors.lastname: Hess
mesh_terms: D000328:Adult; D004417:Dyspnea / Q000209:etiology*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D007432:Intraoperative Period; D007818:Laryngeal Diseases / Q000601:surgery*; D007819:Laryngeal Edema / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011239:Prednisolone / Q000008:administration & dosage*; D012307:Risk Factors
chemical_list: D011239:Prednisolone