title: One-pot beta-substitution of enones with alkyl groups to beta-alkyl enones.
abstract: Vinylic hydrogens at the beta-position of enones were effectively substituted with alkyl groups in a one-pot procedure to afford beta-alkyl enones in good to high isolated yields by conjugate addition of higher-order dialkyl cyanocuprates to enones, followed by a reaction with N-tert-butylbenzenesulfinimidoyl chloride at -78 degree C.
authors.affiliation: Center for Basic Research, Kitasato Institute, 1-15-1-S105, Kitasato, Sagamihara, Kanagawa 228-8555, Japan. matuo@lisci.kitasato-u.ac.jp.
authors.forename: Jun-Ichi
authors.initials: J
authors.lastname: Matsuo
authors.forename: Yayoi
authors.initials: Y
authors.lastname: Aizawa