title: Quorum sensing negatively controls type III secretion regulon expression in Pseudomonas aeruginosa PAO1.
abstract: A systematic analysis of the type III secretion (T3S) genes of Pseudomonas aeruginosa strain PAO1 revealed that they are under quorum-sensing control. This observation was supported by the down-regulation of the T3S regulon in the presence of RhlR-C4HSL and the corresponding advanced secretion of ExoS in a rhlI mutant.
authors.affiliation: Laboratoire d'Ingénierie des Systèmes Macromoléculaires, CNRS-IBSM-UPR9027, 31 Chemin Joseph Aiguier, 13402 Marseille Cedex 20, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Bleves
authors.forename: Chantal
authors.initials: C
authors.lastname: Soscia
authors.forename: Patricia
authors.initials: P
authors.lastname: Nogueira-Orlandi
authors.forename: Andrée
authors.initials: A
authors.lastname: Lazdunski
authors.forename: Alain
authors.initials: A
authors.lastname: Filloux
mesh_terms: D036002:ADP Ribose Transferases / Q000235:genetics / Q000378:metabolism*; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D001427:Bacterial Toxins / Q000235:genetics / Q000378:metabolism; D002118:Calcium / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D007763:Lac Operon; D009154:Mutation; D009876:Operon / Q000502:physiology; D011401:Promoter Regions, Genetic / Q000502:physiology; D011550:Pseudomonas aeruginosa / Q000235:genetics* / Q000502:physiology*; D018085:Regulon / Q000502:physiology*; D015534:Trans-Activators / Q000235:genetics / Q000378:metabolism
chemical_list: D001426:Bacterial Proteins; D001427:Bacterial Toxins; D004268:DNA-Binding Proteins; C095092:ExsA protein, bacteria; C086515:RhlR protein, Pseudomonas aeruginosa; D015534:Trans-Activators; D036002:ADP Ribose Transferases; C444820:exoenzyme S; D002118:Calcium