title: Larvicidal, miracidiacidal and cercaricidal activities of the Egyptian plant Iris pseudacorus.
abstract: The larvicidal properties of Iris pseudacorus leaves ethanol extract against second-instar larvae of two mosquito species, Culex pipiens and Aedes caspius (Diptera: Culicidae) were studied. It was observed that the larvicidal effect of this extract was dose-dependent. The LC50 values of I. pseudacorus against C. pipiens and A. caspius were 10.36 and 16.43 mg/l within 24 hr, and 7.36 and 10.1 mg/l within 48 hr, respectively. The miracidiacidal and cercaricidal properties of I. pseudacorus extract were directly tested against Schistosoma mansoni miracidia and cercariae and a time-concentration relationship was observed. The concentrations needed to kill all miracidia (LC100) within 5 min., 30 min. and an hr of exposure were 2.7, 1.6 and 0.9 mg/l respectively. The concentrations needed to kill all cercariae (LC100) within 5 min. 30 min. and an hr of exposure were 1.5, 1.0 and 0.6 mg/l respectively.
authors.affiliation: National Hepatology and Tropical Medicine Research Institute, General Organization of Teaching Hospitals and Institutes, Cairo, Egypt.
authors.forename: Amer H
authors.initials: AH
authors.lastname: Ahmed
authors.forename: Eman M
authors.initials: EM
authors.lastname: El Hamshary
mesh_terms: D000330:Aedes / Q000187:drug effects / Q000254:growth & development; D000818:Animals; D003465:Culex / Q000187:drug effects / Q000254:growth & development; D004305:Dose-Response Relationship, Drug; D000431:Ethanol; D007306:Insecticides / Q000494:pharmacology*; D031323:Iris Plant / Q000737:chemistry*; D007814:Larva / Q000187:drug effects; D007928:Lethal Dose 50; D051379:Mice; D010572:Pest Control, Biological / Q000379:methods; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D013997:Time Factors
chemical_list: D007306:Insecticides; D010936:Plant Extracts; D000431:Ethanol