Chlamydia pneumoniae infection as a trigger for a Cogan's syndrome.
Cogan's syndrome is often preceded by upper respiratory tract symptoms. The only reported specific agent possibly involved in pathogenesis of the Cogan's syndrome was Chlamydia pneumoniae. Positive IgA, IgM and IgG antibodies against C. pneumoniae in our patient suggest possibility of Chlamydia's role as a trigger for the vasculitis.
Lepur
Dragan
D
Department of Neuroinfections and Intensive Care Medicine, University Hospital for Infectious Diseases Dr Fran Mihaljević, Mirogojska 8, 10000 Zagreb, Croatia. lepurix@inet.hr
Vranjican
Zoran
Z
Himbele
Josip
J
Klinar
Igor
I
Barsić
Bruno
B
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001327:Autoimmune Diseases / Q000188:drug therapy / Q000209:etiology*; D023521:Chlamydophila Infections / Q000150:complications* / Q000188:drug therapy; D016993:Chlamydophila pneumoniae / Q000302:isolation & purification*; D003520:Cyclophosphamide / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D008775:Methylprednisolone