Abdominal CT findings may suggest coeliac disease.
BACKGROUND
Coeliac disease is the most common gastrointestinal immunological disorder in the western countries. Many adult patients present non-specific symptoms and signs of malabsorption such as chronic diarrhoea, anaemia, weight loss and abdominal distention. In non-specific and doubtful conditions, computed tomography is often the first medical examination performed. In a clinical practice, a critical review of computed tomography signs is therefore mandatory.


OBJECTIVE
To evaluate the abdominal computed tomography findings, which are useful to suggest the presence of coeliac disease in adult patients.


METHODS
The computed tomography studies of 28 coeliac patients were reviewed, looking for any intestinal and extraintestinal abnormality. The computed tomography findings evaluated were: abnormalities of intestinal fold pattern, bowel dilatation, fluid and air excess, duodenal abnormalities, intestinal intussusception, bowel wall thickening, lymphadenopathy, ascites, intestinal stenosis, mesenteric vascular changes. The abdominal computed tomography of a group of 30 normal subjects was also analysed.


RESULTS
Intestinal fold pattern abnormalities were seen in 23/28 patients. Intestinal dilatation was seen in 21/28. Fluid excess in 18/28 and lymphadenopathy was seen in 12/28 patients; engorgement of mesenteric vessels in 7/28. Bowel wall thickening was observed in 6/28 patients and transient intussusception was observed in 6/28 patients. Increased air content within the bowel in 4/28 and ascites in 2/28 patients. Bowel dilatation together with fluid excess was observed in 18/28 patients. None of the above mentioned abnormalities abnormalities were seen in normal subjects.


CONCLUSIONS
Data of the present study show that several abdominal computed tomography findings may be seen in coeliac adult patients; these findings should be taken into consideration with a high in level of suspicion by radiologists, to avoid diagnostic delay and unnecessary diagnostic and therapeutic procedures.
Tomei
E
E
Department of Clinical Sciences, Policlinico Umberto I, University "La Sapienza", 155-00161 Rome, Italy.
Diacinti
D
D
Marini
M
M
Mastropasqua
M
M
Di Tola
M
M
Sabbatella
L
L
Picarelli
A
A
D000328:Adult; D000368:Aged; D000388:Air; D001201:Ascites / Q000000981:diagnostic imaging; D001826:Body Fluids / Q000378:metabolism; D016022:Case-Control Studies; D002446:Celiac Disease / Q000175:diagnosis*; D003108:Colonic Diseases / Q000000981:diagnostic imaging; D003251:Constriction, Pathologic / Q000000981:diagnostic imaging; D004108:Dilatation, Pathologic / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism; D007422:Intestines / Q000473:pathology*; D007443:Intussusception / Q000000981:diagnostic imaging; D008206:Lymphatic Diseases / Q000000981:diagnostic imaging; D008297:Male; D008638:Mesenteric Arteries / Q000503:physiopathology; D008642:Mesenteric Veins / Q000503:physiopathology; D008875:Middle Aged; D012039:Regional Blood Flow; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed