title: Recurrence of primary hepatic carcinoid tumor in the remnant liver 13 yr after resection.
abstract: We report here a case of primary hepatic carcinoid tumor (PHCT) recurring in the remnant liver 13 yr and 10 mo after first resection. A 70-yr-old man developed four hypervascular tumors in the liver in December 2003. He had undergone curative left-lobe hepatectomy for PHCT in February 1990. Histopathological examination of the tumor biopsy specimen showed that the tumor was composed of uniform round-to-oval cells with solid arrangement and the tumor cells stained positive for chromogranin A, synaptophysin, and neuron-specific enolase. We diagnosed this case as an intrahepatic metastasis of PHCT with a long latency period, based on the fact that no primary site of carcinoid tumor could be found despite intensive examination and the immunohistochemical findings of the resected tumors were essentially same as those of PHCT in 1990. Although PHCT is reported to have a more favorable prognosis than other hepatic cancer or metastatic carcinoid tumor in the liver, long-term observation is recommended.
authors.affiliation: Center for Gastroenterology, Teine Keijinkai Hospital, 1-12-1-40 Maeda, Teine-ku, Sapporo, 006-8555, Japan. nisimori.tdr@keijinkai.or.jp
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nishimori
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Tsuji
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Miyamoto
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Sakurai
authors.forename: Shinya
authors.initials: S
authors.lastname: Mitsui
authors.forename: Jong-Hon
authors.initials: JH
authors.lastname: Kang
authors.forename: Masafumi
authors.initials: M
authors.lastname: Yoshida
authors.forename: Masashi
authors.initials: M
authors.lastname: Nomura
authors.forename: Itokawa
authors.initials: I
authors.lastname: Fuminori
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Ishiwatari
authors.forename: Takahiro
authors.initials: T
authors.lastname: Matsunaga
authors.forename: Manabu
authors.initials: M
authors.lastname: Osanai
authors.forename: Akio
authors.initials: A
authors.lastname: Katanuma
authors.forename: Kuniyuki
authors.initials: K
authors.lastname: Takahashi
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Anbo
authors.forename: Tomoshige
authors.initials: T
authors.lastname: Masuda
authors.forename: Nobuichi
authors.initials: N
authors.lastname: Kashimura
authors.forename: Toshiya
authors.initials: T
authors.lastname: Shinohara
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Maguchi
mesh_terms: D000368:Aged; D002276:Carcinoid Tumor / Q000473:pathology* / Q000601:surgery*; D006498:Hepatectomy; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000473:pathology* / Q000601:surgery*; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery*; D013997:Time Factors