title: Corpus callosum changes following shunting for hydrocephalus: case report and review of the literature.
abstract: Diffuse callosal signal changes can rarely occur following successful shunting for obstructive hydrocephalus. We report on a patient who underwent ventriculoperitoneal shunting for aqueductal stenosis and required two revisions for neurological deterioration and presumed shunt malfunction. Extensive changes involving the corpus callosum, periventricular white matter and optic chiasm were noted after the first, and were prominent after second shunt revision. Thus, post-shunting callosal changes may be associated with more extensive white matter disease, and may not imply wide pressure fluctuations. However, they need not prompt further intervention.
authors.affiliation: Division of Clinical Neurology, University Hospital Queen's Medical Centre, Medical School B Floor, Nottingham NG7 2UH, UK. cris.constantinescu@nottingham.ac.uk
authors.forename: C S
authors.initials: CS
authors.lastname: Constantinescu
authors.forename: N S
authors.initials: NS
authors.lastname: McConachie
authors.forename: B D
authors.initials: BD
authors.lastname: White
mesh_terms: D000328:Adult; D002557:Cerebrospinal Fluid Shunts; D003337:Corpus Callosum / Q000473:pathology*; D006801:Humans; D006849:Hydrocephalus / Q000473:pathology / Q000601:surgery*; D008297:Male