Comparison between monkey and human visual fields using a personal computer system.
To use monkeys as models for eye diseases that may lead to blindness, we need to develop a method to precisely measure its visual field and to understand similarities and differences in visual field properties between monkeys and humans. The visual field of monkey was not measured precisely although the necessity. We established a new system with personal computers for precise measurement of the monkey visual field. Four monkeys and three humans served as subjects. The luminance-contrast sensitivity of the central 24 degrees field was measured while the subject was fixating a small spot. During the measurement, we continuously recorded the eye position, and discarded the data when fixation was broken. Reliability indices demonstrated high and stable behavioral performance by both monkeys and humans. The luminance-contrast sensitivity was highest around the fovea, and declined as eccentricity increased. The blind spot was clearly detected 15 degrees temporally. The overall sensitivity was higher in humans than in monkeys and the sensitivity dropped more sharply in the periphery in monkeys than in humans. We recommend this system as a convenient and reliable way to measure visual functions in monkeys in basic ophthalmologic research or in assessment of the drug effects on the visual field.
Sasaoka
Masaaki
M
Department of Behavioral and Brain Sciences, Primate Research Institute, Kyoto University, Aichi, Japan.
Hara
Hideaki
H
Nakamura
Katsuki
K
D000328:Adult; D000465:Algorithms; D000818:Animals; D001522:Behavior, Animal; D015350:Contrast Sensitivity / Q000502:physiology*; D004307:Dose-Response Relationship, Radiation; D005133:Eye Movements / Q000502:physiology; D007839:Functional Laterality; D006801:Humans; D008252:Macaca fascicularis; D008297:Male; D008838:Microcomputers; D009898:Optic Disk / Q000502:physiology; D010775:Photic Stimulation / Q000295:instrumentation / Q000379:methods; D015203:Reproducibility of Results; D012684:Sensory Thresholds / Q000502:physiology; D013997:Time Factors; D014794:Visual Fields / Q000502:physiology*