Suppression of thyroarytenoid muscle responses during repeated air pressure stimulation of the laryngeal mucosa in awake humans.
Repeated stimulation of the laryngeal mucosa occurs during speech. Single stimuli, however, can elicit the laryngeal adductor response (LAR). Our hypothesis was that the LAR to repeated rapid air pressure stimuli is centrally suppressed in humans. Hooked-wire electrodes were inserted into the thyroarytenoid and cricothyroid muscles on both sides and into the posterior cricoarytenoid muscle on one side. Pairs of air puff stimuli were presented to the mucosa over the arytenoids at pressure levels three times threshold with interstimulus intervals from 250 to 5,000 ms. Bilateral thyroarytenoid responses occurred at around 150 ms to more than 70% of the initial stimuli. With repeated presentation at intervals of 2 seconds or less, the percent occurrence decreased to less than 40% and response amplitudes were reduced by 50%. Central suppression of adductor responses to repeated air puff stimuli may allow speakers to produce voice without eliciting reflexive spasms that could disrupt speech.
Kearney
Pamela Reed
PR
Laryngeal and Speech Section, National Institute of Neurological Disorders and Stroke, Building 10, Room 5D38, Bethesda, MD 20892, USA.
Poletto
Christopher J
CJ
Mann
Eric A
EA
Ludlow
Christy L
CL
D000328:Adult; D000368:Aged; D000392:Air Movements; D000704:Analysis of Variance; D004576:Electromyography; D005260:Female; D006801:Humans; D007820:Laryngeal Mucosa / Q000502:physiology*; D007821:Laryngeal Muscles / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D010812:Physical Stimulation; D011312:Pressure; D012684:Sensory Thresholds / Q000502:physiology*