Identification of novel anthrax lethal factor inhibitors generated by combinatorial Pictet-Spengler reaction followed by screening in situ.
Numa
Mehdi M D
MM
Department of Chemistry, Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, BCC-338, La Jolla, CA 92037, USA.
Lee
Lac V
LV
Hsu
Che-Chang
CC
Bower
Kristen E
KE
Wong
Chi-Huey
CH
D000881:Anthrax; D000942:Antigens, Bacterial; D001427:Bacterial Toxins / Q000037:antagonists & inhibitors*; D002470:Cell Survival / Q000187:drug effects*; D020650:Combinatorial Chemistry Techniques; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D008403:Mass Screening; D015394:Molecular Structure
D000942:Antigens, Bacterial; D001427:Bacterial Toxins; D004791:Enzyme Inhibitors; C030325:anthrax toxin