title: Intralesional corticosteroid injection for central giant cell granuloma: a case report and review of the literature.
abstract: Central giant cell granuloma (CGCG) is a benign intraosseous lesion of the jaws that is found predominantly in children and young adults. Although benign, it may be locally aggressive, causing extensive bone destruction, tooth displacement and root resorption. The common therapy is aggressive curettage, peripheral ostectomy or resection, which may be associated with loss of teeth and, in younger patients, loss of dental germs. A number of alternative nonsurgical approaches have been advocated in recent years for the management of CGCGs. These include intralesional corticosteroid injections, calcitonin injections and subcutaneous alpha-interferon injections. In this article, an 1-year-old boy with a CGCG is successfully treated with corticosteroid injections and this treatment is discussed within a review of the literature.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Ege University Faculty of Dentistry, Izmir, Turkey.
authors.forename: Bahar
authors.initials: B
authors.lastname: Sezer
authors.forename: Banu
authors.initials: B
authors.lastname: Koyuncu
authors.forename: Murat
authors.initials: M
authors.lastname: Gomel
authors.forename: Tayfun
authors.initials: T
authors.lastname: Günbay
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D006101:Granuloma, Giant Cell / Q000188:drug therapy*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008336:Mandibular Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones