[Hereditary angioneurotic edema: a case report in a 3-year-old child].
Hereditary angioneurotic edema is a dominant autosomal disease (incidence 1/150,000), whose diagnosis is crucial as this condition can lead to fatal asphyxia within minutes. We report the case of a three-year-old girl, misdiagnosed as allergic asthma. Recognition of the syndrome led to adapted care restoring normal family and school life. Pathogenic cascades involved and therapeutic principles of this disease are reviewed.
El-Hachem
C
C
Service de pédiatrie, centre hospitalier Robert-Bisson, 14100 Lisieux, France. celhachem@ch-lisieux.fr
Amiour
M
M
Guillot
M
M
Laurent
J
J
D000322:Adrenergic Agonists / Q000627:therapeutic use; D000799:Angioedema / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000933:Antifibrinolytic Agents / Q000627:therapeutic use; D001249:Asthma / Q000175:diagnosis; D002675:Child, Preschool; D003174:Complement C1 Inactivator Proteins / Q000627:therapeutic use; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D004359:Drug Therapy, Combination; D004837:Epinephrine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use; D010375:Pedigree; D014148:Tranexamic Acid / Q000627:therapeutic use; D016896:Treatment Outcome
D000322:Adrenergic Agonists; D000893:Anti-Inflammatory Agents; D000933:Antifibrinolytic Agents; D003174:Complement C1 Inactivator Proteins; D014148:Tranexamic Acid; D008775:Methylprednisolone; D004837:Epinephrine