title: [Proximal pancreatectomy in a case of nesidioblastosis].
abstract: A 19 moth-old child who presented seizures secondary to intractable hypoglycemia, fulfilling the clinical and biochemical criteria for hyperinsulinism was studied. Histopathological findings of the pancreas showed the presence of small clusters of b cell islets throughout acinar tissue near ducts, in both the head and the proximal third of the body. Proximal pancreatectomy (60%) and distal pancreatic-jejunostomy (Roux-in-Y) were performed. This procedure was effective in reverting hypoglycemia and constitutes the first successful alternative treatment.
authors.affiliation: Laboratorio de Bioquímica, Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara. drljfiores@hotmail.com
authors.forename: Luis Javier
authors.initials: LJ
authors.lastname: Flores-Alvarado
authors.forename: Sergio
authors.initials: S
authors.lastname: Sánchez-Enríquez
authors.forename: Abraham Zepeda
authors.initials: AZ
authors.lastname: Moreno
authors.forename: Sergio Alberto
authors.initials: SA
authors.lastname: Ramírez-Garcial
authors.forename: Miriam Ruth
authors.initials: MR
authors.lastname: Bueno-Topete
authors.forename: Mónica
authors.initials: M
authors.lastname: Ayub-Ayala
authors.forename: Lucía Sagrario
authors.initials: LS
authors.lastname: del Vázquez-López
authors.forename: Antonio
authors.initials: A
authors.lastname: Gallardo-Meza
authors.forename: Patricia
authors.initials: P
authors.lastname: Nuño-Moren
authors.forename: César Enrique
authors.initials: CE
authors.lastname: Gaspar-Barba
mesh_terms: D003940:Diagnostic Techniques, Endocrine; D006801:Humans; D006946:Hyperinsulinism / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D007003:Hypoglycemia / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D007223:Infant; D008297:Male; D046768:Nesidioblastosis / Q000150:complications* / Q000473:pathology / Q000601:surgery; D010179:Pancreas / Q000473:pathology / Q000601:surgery; D010180:Pancreatectomy / Q000379:methods; D016896:Treatment Outcome