The psychotic spectrum: validity and reliability of the Structured Clinical Interview for the Psychotic Spectrum.
This study evaluates the validity and the reliability of a new instrument developed to assess the psychotic spectrum: the Structured Clinical Interview for the Psychotic Spectrum (SCI-PSY). The instrument is based on a spectrum model that emphasizes soft signs, low-grade symptoms, subthreshold syndromes, as well as temperamental and personality traits comprising the clinical and subsyndromal psychotic manifestations. The items of the interview include, in addition to a subset of the DSM-IV criteria for psychotic syndromes, a number of features derived from clinical experience and from a review of the phenomenological descriptions of psychoses. Study participants were enrolled at 11 Italian Departments of Psychiatry located at 9 sites and included 77 consecutive patients with schizophrenia or schizoaffective disorder, 66 with borderline personality disorder, 59 with psychotic mood disorders, 98 with non-psychotic mood disorders and 57 with panic disorder. A comparison group of 102 unselected controls was enrolled at the same sites. The SCI-PSY significantly discriminated subjects with any psychiatric diagnosis from controls and subjects with from those without psychotic disorders. The hypothesized structure of the instrument was confirmed empirically.
Sbrana
A
A
Department of Psychiatry, University of Pisa, Via Roma 67, 56127 Pisa, Italy. alfredosbrana@virgilio.it
Dell'Osso
L
L
Benvenuti
A
A
Rucci
P
P
Cassano
P
P
Banti
S
S
Gonnelli
C
C
Doria
M R
MR
Ravani
L
L
Spagnolli
S
S
Rossi
L
L
Raimondi
F
F
Catena
M
M
Endicott
J
J
Frank
E
E
Kupfer
D J
DJ
Cassano
G B
GB
D000293:Adolescent; D000328:Adult; D001883:Borderline Personality Disorder / Q000175:diagnosis / Q000523:psychology; D010054:Brief Psychiatric Rating Scale; D039721:Diagnostic and Statistical Manual of Mental Disorders; D006801:Humans; D007406:Interview, Psychological; D008875:Middle Aged; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000523:psychology; D015203:Reproducibility of Results; D012559:Schizophrenia / Q000175:diagnosis; D012565:Schizophrenic Psychology; D011795:Surveys and Questionnaires