title: Molecular epidemiology and KSHV K1 subtypes in a Cuban AIDS-Kaposi's sarcoma population.
abstract: Kaposi's sarcoma-associated herpesvirus (KSHV) is detected consistently in Kaposi's sarcoma (KS). Because of its dramatic sequence variation, the K1 gene has been used to classify KSHV. We found a diverse array of KSHV subtypes A1, A2, A3, A5, B1, B2, and C3 in 23 Cuban KS samples containing several novel sporadic insertions/deletions in subtypes A and C. The molecular epidemiology of the KSHV subtypes seems to reflect the unique mixed ethnic background of the Cuban population.
authors.affiliation: Department of Virology, Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba.
authors.forename: Vivian
authors.initials: V
authors.lastname: Kouri
authors.forename: Xiaozhen
authors.initials: X
authors.lastname: Liang
authors.forename: Maria Elena
authors.initials: ME
authors.lastname: Rodriguez
authors.forename: Virginia
authors.initials: V
authors.lastname: Capo
authors.forename: Sonia
authors.initials: S
authors.lastname: Resik
authors.forename: Julio
authors.initials: J
authors.lastname: Barrios
authors.forename: Beatriz
authors.initials: B
authors.lastname: Mantecon
authors.forename: Orestes
authors.initials: O
authors.lastname: Blanco
authors.forename: Robert
authors.initials: R
authors.lastname: Means
authors.forename: Jae U
authors.initials: JU
authors.lastname: Jung
authors.forename: Bok-Soo
authors.initials: BS
authors.lastname: Lee
authors.forename: Ulrich R
authors.initials: UR
authors.lastname: Hengge
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000595:Amino Acid Sequence; D003462:Cuba / Q000453:epidemiology; D005260:Female; D005814:Genes, Viral; D019288:Herpesvirus 8, Human / Q000145:classification* / Q000235:genetics; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D010802:Phylogeny; D012514:Sarcoma, Kaposi / Q000453:epidemiology / Q000821:virology*