Antimicrobial activity of clerodane diterpenoids from Polyalthia longifolia seeds.
The diterpenoids 16alpha-hydroxy-cleroda-3,13 (14)-Z-diene-15,16-olide (1) and 16-oxo-cleroda-3, 13(14)-E-diene-15-oic acid (2), isolated from the hexane extract of the seeds of Polyalthia longifolia, demonstrated significant antibacterial and antifungal activities.
Marthanda Murthy
M
M
Organic Chemistry Division II, Indian Institute of Chemical Technology, Hyderabad 500 007, India.
Subramanyam
M
M
Hima Bindu
M
M
Annapurna
J
J
D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D004224:Diterpenes / Q000737:chemistry / Q000494:pharmacology*; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D015394:Molecular Structure; D031044:Polyalthia / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry*
C502753:16-oxo-cleroda-3, 13(14)-E-diene-15-oic acid; C502752:16alpha-hydroxy-cleroda-3,13 (14)-Z-diene-15,16-olide; D000900:Anti-Bacterial Agents; D004224:Diterpenes