Intracranial meningiomas of childhood and adolescence.
Meningiomas are rare intracranial neoplasms in childhood and adolescence, representing 0.4-4.1% of the pediatric-age tumors and 1.5-1.8% of all intracranial meningiomas. The goal of this study was to determine epidemiology, clinical and radiological features, and long-term outcome of childhood and adolescence meningiomas. Patients operated for intracranial meningiomas of childhood and adolescence between 1983 and 2003 at Gazi University School of Medicine, Department of Neurosurgery, were evaluated retrospectively. This study presents 11 cases (6 male, 5 female), ranging in age from 14 months to 17 years. Age and sex distribution, presenting symptoms, neurological examination results, location of meningiomas, radiological and histopathological findings, and prognosis were reviewed. The results were compared with those reported in the existing literature. Atypical and malignant meningiomas seem to be more common in childhood and adolescence with respect to adult meningiomas. Tumor location, completeness of tumor removal, and pathological grade are the most important prognostic factors.
Tufan
Kadir
K
Department of Neurosurgery, Gazi University Medical School, Ankara, Turkey. ktufan@gazi.edu.fr
Dogulu
Fikret
F
Kurt
Gokhan
G
Emmez
Hakan
H
Ceviker
Necdet
N
Baykaner
M Kemali
MK
D000293:Adolescent; D017677:Age Distribution; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery*; D008579:Meningioma / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery*; D011379:Prognosis; D011859:Radiography; D012189:Retrospective Studies; D017678:Sex Distribution; D014421:Turkey / Q000453:epidemiology