Recurrent bilateral mammary fibromatosis (desmoid tumor) imaged with technetium-99m pentavalent dimercaptosuccinic acid [99mTc-(V)DMSA] scintimammography.
BACKGROUND
Breast fibromatosis is a rare, benign, recurring, locally destructive entity.


METHODS
A 35-year-old woman underwent right-sided lumpectomy, revealing fibromatosis with epithelial hyperplasia. Two years later, she was re-evaluated due to a three times as large mass recurrence on X-ray mammography. (99m)Tc-(V)DMSA scintimammography revealed diffuse increased radiotracer uptake occupying the entire breast. A less widespread similar uptake was observed in the contralateral breast. Mammography did identify neither the posterior margins of the mass nor the left-sided lesion. The patient underwent mastectomy and left-sided open biopsy, revealing bilateral fibromatosis. Ki-67 expression was moderate.


CONCLUSIONS
(99m)Tc-(V)DMSA scintimammography can provide information regarding the nature of the lesion, its extent and bilateral involvement (especially in dense breasts) and could prove useful as a predictor of its potential for recurrence.
Papantoniou
Vassilios
V
Department of Nuclear Medicine, ALEXANDRA University Hospital, 80, Vas. Sophia's Ave. and 2, K. Lourou Str., 115 28 Athens, Greece. vpap@spark.net.gr
Koutsikos
John
J
Sotiropoulou
Maria
M
Feida
Eleni
E
Tsiouris
Spyridon
S
D000328:Adult; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D018222:Desmoid Tumors / Q000000981:diagnostic imaging*; D006801:Humans; D008327:Mammography / Q000379:methods; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013667:Technetium; D019783:Technetium Tc 99m Dimercaptosuccinic Acid
D019275:Radiopharmaceuticals; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D013667:Technetium