Microfabrication of encoded microparticle array for multiplexed DNA hybridization detection.
A strategy for the high-sensitivity, high-selectivity, and multiplexed detection of oligonucleotide hybridizations has been developed with an encoded Ni microparticle random array that was manufactured by a "top-down" approach using micromachining and microfabrication techniques.
Zhi
Zheng-Liang
ZL
School of Materials Science, Japan Advanced Institute of Science and Technology, 1-1, Asahidai, Tatsunokuchi, Ishikawa 923-1292, Japan. zzhi@liv.ac.uk.
Morita
Yasutaka
Y
Yamamura
Shouhei
S
Tamiya
Eiichi
E
D001710:Biotin / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D016650:Fluorescein-5-isothiocyanate; D005456:Fluorescent Dyes; D008856:Microscopy, Fluorescence; D053758:Nanoparticles; D036103:Nanotechnology / Q000379:methods*; D009532:Nickel / Q000737:chemistry; D009693:Nucleic Acid Hybridization; D009841:Oligonucleotides / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
D005456:Fluorescent Dyes; D009841:Oligonucleotides; D001710:Biotin; D009532:Nickel; D004247:DNA; D016650:Fluorescein-5-isothiocyanate