title: Endoscopic-assisted cranionasal resection of olfactory neuroblastoma.
abstract: BACKGROUND
  Cranionasal resection was first described in 1997 for the surgical resection of olfactory neuroblastoma. The endoscopic transnasal approach is used in cranionasal resection to replace the more invasive craniofacial resection. It has the advantages of avoiding the facial wound and its associated pain, swelling, and scar. The authors have routinely practiced cranionasal resection since 1996 for resection of all anterior skull base tumors in which the resultant skull base bony defect is limited to the nasal and sinus roof. The aim of this study was to review the results of cranionasal resection for olfactory neuroblastoma.
  
  
  METHODS
  The results of cranionasal resection for olfactory neuroblastoma in six patients from 1996 to 2003 were reviewed.
  
  
  RESULTS
  The Kadesh stages were 3A, 2B, and 1C. None of the patients had postoperative complications. Postoperative radiotherapy was given only to the patient with Kadesh stage C disease. There were no local recurrences. Two patients died of lung metastasis.
  
  
  CONCLUSIONS
  Cranionasal resection is a safe and adequate procedure. Postoperative radiotherapy is not necessary after clear resection of Kadesh A and B tumors.
authors.affiliation: Division of Otorhinolaryngology, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong. pwyuen@hkucc.hku.hk
authors.forename: Anthony Po-Wing
authors.initials: AP
authors.lastname: Yuen
authors.forename: Yiu Wah
authors.initials: YW
authors.lastname: Fan
authors.forename: Ching Fai
authors.initials: CF
authors.lastname: Fung
authors.forename: Kwan Ngai
authors.initials: KN
authors.lastname: Hung
mesh_terms: D000328:Adult; D000368:Aged; D004724:Endoscopy; D018304:Esthesioneuroblastoma, Olfactory / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome