title: [Ophthalmologic symptomatology in children with periventricular leucomalation].
abstract: Ophthalmologic symptoms were analyzed in 76 children with periventricular leucomalation (PL). Clinical or functional ophthalmic disorders were detected in 100% of patients. Changes in the optic nerve disc were diagnosed in 93.4% of patients. The syndrome of dilated excavation (SDE), i.e. dilation and cupping of the optic nerve disc combined in all cases with affection of postgenicular visual paths (of optic radiation and/or striatal cortex) verified by neuroradiology, was most frequently (80.3%) encountered in children with PL. Presumably, the progression of SDE is associated with transsynaptic retrograde degeneration conditioned by the hypoxic-ischemic affection of the CNS in the projection of postgenicular visual paths at pre- and perinatal stages. SDE is an important criterion in the diagnosis of lesions of postgenicular visual paths in babies.
authors.forename: I M
authors.initials: IM
authors.lastname: Mosin
authors.forename: L K
authors.initials: LK
authors.lastname: Moshetova
authors.forename: N V
authors.initials: NV
authors.lastname: Slavinskaia
authors.forename: N V
authors.initials: NV
authors.lastname: Vasil'eva
authors.forename: I A
authors.initials: IA
authors.lastname: Letneva
authors.forename: O V
authors.initials: OV
authors.lastname: Shuleshko
mesh_terms: D002648:Child; D002675:Child, Preschool; D018450:Disease Progression; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007969:Leukomalacia, Periventricular / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D009898:Optic Disk / Q000000981:diagnostic imaging / Q000473:pathology; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D011379:Prognosis; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D014792:Visual Acuity / Q000502:physiology; D014794:Visual Fields / Q000502:physiology