title: Four tetranortriterpenoids from the stem bark of Khaya anthotheca.
abstract: Eight limonoids, anthothecanolide (1), 3-O-acetylanthothecanolide (2), 2,3-di-O-acetylanthothecanolide (3), 6R,8alpha-dihydroxycarapin (4), 3beta-acetoxy-3-deoxo-6R-hydroxycarapin (5), methyl angolensate, methyl 6-hydroxyangolensate and khayalactone together with sitosterol glucoside, have been isolated from the extracts of the stem bark of Khaya anthotheca. Compounds 1-4 are described for the first time. Their structures were established by analysis of the high-field NMR and MS data. The structure of compound 4 was confirmed by a single crystal X-ray structure analysis.
authors.affiliation: Department of Chemistry, University of Dschang, Box 67, Dschang, Cameroon.
authors.forename: Michel K
authors.initials: MK
authors.lastname: Tchimene
authors.forename: Pierre
authors.initials: P
authors.lastname: Tane
authors.forename: Dieudonne
authors.initials: D
authors.lastname: Ngamga
authors.forename: Joseph D
authors.initials: JD
authors.lastname: Connolly
authors.forename: Louis J
authors.initials: LJ
authors.lastname: Farrugia
mesh_terms: D036701:Limonins / Q000737:chemistry*; D029582:Meliaceae / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry*
chemical_list: D036701:Limonins