Interest of postmortem-collected specimens in the diagnosis of fulminant meningococcal sepsis.
We reported the case of a child who died of purpura fulminans. The diagnosis of Neisseria meningitidis serogroup C could be assessed using postmortem specimens collected up to 10 h after death. We were able to identify the bacteria by culture and/or PCR on samples without having autopsy performed. Soluble antigens were also detected in serum.
Ploy
Marie-Cécile
MC
Laboratoire de Bactériologie-Virologie-Hygiène, CHU Dupuytren, 87042 Limoges Cedex, France. marie-cecile.ploy@unilim.fr
Garnier
Fabien
F
Languepin
Jeanne
J
Fermeaux
Véronique
V
Martin
Christian
C
Denis
François
F
D000942:Antigens, Bacterial / Q000097:blood; D001344:Autopsy; D003470:Culture Media; D017809:Fatal Outcome; D006801:Humans; D011695:IgA Vasculitis / Q000175:diagnosis* / Q000382:microbiology; D007223:Infant; D008297:Male; D008589:Meningococcal Infections / Q000175:diagnosis* / Q000382:microbiology; D038542:Neisseria meningitidis, Serogroup C / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D018805:Sepsis / Q000175:diagnosis* / Q000382:microbiology; D013048:Specimen Handling / Q000379:methods
D000942:Antigens, Bacterial; D003470:Culture Media