title: Correlates of regular fish consumption in French elderly community dwellers: data from the Three-City study.
abstract: OBJECTIVE
  Several studies have found an inverse association between fish consumption and risk of dementia. The objective of this study was to describe the characteristics of older fish consumers, in order to identify potential confounders in this relationship.
  
  
  METHODS
  Cross-sectional analysis of the baseline data of a prospective cohort study.
  
  
  METHODS
  Bordeaux, Dijon, and Montpellier (France) in 1999-2000.
  
  
  METHODS
  A total of 9280 community dwellers aged 65 y and above participating in the baseline examination of the Three-City Study.
  
  
  METHODS
  All participants answered a face-to-face interview and underwent a physical examination. Cross-sectional analyses were performed by logistic regressions.
  
  
  RESULTS
  Regular fish consumers (at least weekly) had a higher education (OR from 1.19 to 1.65, P = 0.0003) and income (OR from 1.37 to 1.89, P < 0.0001). Controlling for age, sex, education, and city, they had a higher consumption of pulses, fruit, and vegetables (P < 0.001). They were more often alcohol drinkers (P < 0.0001). They felt in better health (P < 0.05), exhibited less depressive symptoms (P < 0.001), and scored higher on the Mini Mental Status Examination (P < 0.05). However, their objective physical health status was not better, except that they were leaner. They suffered more often from hypertension and past stroke.
  
  
  CONCLUSIONS
  Socioeconomic status, dietary habits, depression, and vascular risk factors could act as confounders in the relationship between fish consumption and risk of dementia.
authors.affiliation: INSERM U593, Université Victor Ségalen Bordeaux 2, Bordeaux, France. Pascale.Barberger-Gateau@isped.u-bordeaux2.fr
authors.forename: P
authors.initials: P
authors.lastname: Barberger-Gateau
authors.forename: M A
authors.initials: MA
authors.lastname: Jutand
authors.forename: L
authors.initials: L
authors.lastname: Letenneur
authors.forename: S
authors.initials: S
authors.lastname: Larrieu
authors.forename: B
authors.initials: B
authors.lastname: Tavernier
authors.forename: C
authors.initials: C
authors.lastname: Berr
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology; D000428:Alcohol Drinking; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D003704:Dementia / Q000453:epidemiology* / Q000209:etiology; D003863:Depression / Q000453:epidemiology; D004032:Diet; D004034:Diet Surveys; D004522:Educational Status; D005247:Feeding Behavior; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors; D017747:Seafood; D012959:Socioeconomic Factors; D014652:Vascular Diseases / Q000453:epidemiology