title: p53 gene (Gendicine) and embolisation overcame recurrent hepatocellular carcinoma.
abstract: Transcatheter arterial chemoembolisation (TACE) has become the standard treatment for unresectable hepatocellular carcinoma (HCC). However, this method is often unsuccessful. The p53 gene, which is present as a mutant form in many human tumours, is known to have broad spectrum antitumour effects when expressed normally. In this study, we report a 23 year old patient with recurrent HCC who was treated with the p53 gene (Gendicine) combining TACE, which resulted in a good clinical prognosis.
authors.affiliation: Department of Radiology, West China Hospital, Sichuan University, 37 Guoxuexiang, Chengdu 610041, Sichuan Province, China. YongsongGuan@yahoo.com
authors.forename: Y S
authors.initials: YS
authors.lastname: Guan
authors.forename: Y
authors.initials: Y
authors.lastname: Liu
authors.forename: X P
authors.initials: XP
authors.lastname: Zhou
authors.forename: X
authors.initials: X
authors.lastname: Li
authors.forename: Q
authors.initials: Q
authors.lastname: He
authors.forename: L
authors.initials: L
authors.lastname: Sun
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D016461:Chemoembolization, Therapeutic; D003131:Combined Modality Therapy; D018014:Gene Transfer Techniques; D016158:Genes, p53; D015316:Genetic Therapy / Q000379:methods*; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000628:therapy*; D014057:Tomography, X-Ray Computed