Non-rheumatoid erosive arthritis associated with type I hereditary angioedema.
Hereditary angioedema (HAE) is an autosomal dominant disease that causes recurrent attacks of non-pitting edema of soft tissues, without pruritus. This disorder can also affect internal organs. The cause of HAE consists in quantitative or qualitative defective production of C1 inhibitor (C1-INH). Many autoimmune diseases such as systemic lupus erythematosus (SLE) (or SLE-like syndromes), Sjögren's syndrome, scleroderma, thyroiditis, glomerulonephritis, and inflammatory bowel disease have been described in patients suffering from HAE. A concomitance with pure arthritis was previously reported only in two adult patients. Here, we describe for the first time the association between HAE and a non-rheumatoid erosive oligoarthritis involving hips and wrists.
Palazzi
C
C
Division of Rheumatology, Villa Pini Clinic, Chieti, Italy. kaps57@virgilio.it
D'Amico
E
E
Cacciatore
P
P
Pennese
E
E
Olivieri
I
I
D000799:Angioedema / Q000150:complications / Q000235:genetics* / Q000473:pathology*; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001168:Arthritis / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D019644:Arthroplasty, Replacement, Hip; D005260:Female; D006621:Hip Joint / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D012074:Remission Induction; D016896:Treatment Outcome; D014955:Wrist Joint / Q000473:pathology / Q000503:physiopathology / Q000601:surgery
D018501:Antirheumatic Agents; D006886:Hydroxychloroquine; D008775:Methylprednisolone