title: Alkenyl- and aryl[2-(hydroxymethyl)phenyl]dimethylsilanes: an entry to tetraorganosilicon reagents for the silicon-based cross-coupling reaction.
abstract: Alkenyl- and aryl[2-(hydroxymethyl)phenyl]dimethylsilanes, highly stable tetraorganosilicon reagents, are found to react with aryl and alkenyl iodides in the presence of a palladium catalyst and K2CO3 as a base, significantly milder conditions compared with those ever reported for the silicon-based cross-coupling reactions. The reaction tolerates a wide range of functional groups, including silyl protectors, and allows a gram-scale synthesis to recover and reuse the silicon residue.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan. nakao@npc05.kuic.kyoto-u.ac.jp
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Nakao
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Imanaka
authors.forename: Akhila K
authors.initials: AK
authors.lastname: Sahoo
authors.forename: Akira
authors.initials: A
authors.lastname: Yada
authors.forename: Tamejiro
authors.initials: T
authors.lastname: Hiyama