Toward assessment of blood oxygen saturation by spectroscopic optical coherence tomography.
The use of spectroscopic optical coherence tomography to assess hemoglobin oxygen saturation of whole blood is investigated. We propose to use the differential attenuation coefficient to determine the degree of saturation. Our data show qualitative agreement between the measured differential attenuation coefficients as a function of saturation and predictions based on the oxygen-saturation-dependent absorption and scattering properties of blood.
Faber
Dirk J
DJ
Laser Center, Academic Medical Center, University of Amsterdam, PO. Box 22700, 1100 DE Amsterdam, The Netherlands. d.j.faber@amc.uva.nl
Mik
Egbert G
EG
Aalders
Maurice C G
MC
van Leeuwen
Ton G
TG
D000465:Algorithms; D001774:Blood Chemical Analysis / Q000379:methods*; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D010100:Oxygen / Q000097:blood*; D013057:Spectrum Analysis / Q000379:methods*; D041623:Tomography, Optical Coherence / Q000379:methods*
D006454:Hemoglobins; D010100:Oxygen