title: [Comparative study of the hyperbaric hyperoxygenation in ischemic colonic loops in rats].
abstract: OBJECTIVE
  To analyze and to evaluate the effect of the hyperbaric hyperoxygenation in the mechanical resistance of ischemic colon of rats.
  
  
  METHODS
  Eighty rats, distributed in four groups of 20 animals in each one, were used. In group 1 (G1), the control group, ischemia was not caused. Group 2 was submitted to the lesser degree of ischemia. Group 3 was submitted to the intermediate degree of ischemia. In group 4, a bigger degree of intestinal ischemia was provoked. Each group was divided in two sub-groups often animals each: with hyperbaric chamber (CC) and without hyperbaric chamber (SC). The animals of the four CC subgroups were placed in an experimental hyperbaric chamber in order to inhale oxygen at 100%, at two Absolute Atmospheres, for 120 minutes, for a four-day consecutive period. The animals of the four SC subgroups were kept in environment air during the five days of the experiment. All animals have been submitted to the mechanical study of the intestinal loop by the pressure test of the rupture by liquid distension. The euthanasia occurred in the fifth post-operative day.
  
  
  RESULTS
  Considering the ischemia factor, the four groups were different among them (p=0.0001). There was no statistical difference between subgroups CC and SC (p=0.3461).
  
  
  CONCLUSIONS
  The hyperbaric oxygen-therapy did not present improvement on the induced ischemia in rats upright colic loop.
authors.affiliation: Departamento de Cirurgia, Serviço de Colo-Proctologia da Faculdade de Ciências Médicas da Universidade Estadual de Campinas. angelorocha@terra.com.br
authors.forename: Antonio Angelo
authors.initials: AA
authors.lastname: Rocha
authors.forename: Cláudio Sadi Rodrigues
authors.initials: CS
authors.lastname: Coy
authors.forename: Juvenal Ricardo Navarro
authors.initials: JR
authors.lastname: Góes
authors.forename: Maria Lourdes Setsuko
authors.initials: ML
authors.lastname: de Ayrizono
authors.forename: Feng Chung
authors.initials: FC
authors.lastname: Wu
authors.forename: João José
authors.initials: JJ
authors.lastname: Fagundes
mesh_terms: D000818:Animals; D003106:Colon / Q000098:blood supply*; D006931:Hyperbaric Oxygenation / Q000379:methods; D007511:Ischemia / Q000628:therapy*; D008297:Male; D051381:Rats; D017208:Rats, Wistar