title: Ameloblastoma. Diagnosis by means of FNAB. Report of two cases.
abstract: BACKGROUND
  Ameloblastomas are the most frequent odontogenic tumors of the maxilla. In spite of their benign cytohistological appearance, they behave as invasive recurring tumors, with the possibility of metastasis. FNAB is a rapid, bloodless test that provides a pre-surgical diagnosis, thus, on occasions avoiding the need for diagnostic biopsies. We present the cytological characteristics of two cases of jugal recurrences of mandibular ameloblastomas diagnosed by FNAB, as well as their cytohistological correlation.
  
  
  METHODS
  Two patients, a 36-year-old woman, and a 62-year-old male who both attended with mandibular swelling of a few months evolution. In both cases the first diagnostic approximation was the histological study of the tumoral mass, together with the radiological studies. Following therapeutic extirpation both cases recurred. The diagnosis of the recurrences was established cytologically by means of FNAB. The cytologic smears revealed a granular background with isolated macrophages and giant multinucleate cells and an abundant epithelial cellularity of basaloid appearance arranged in cohesive groups forming images of peripheral palidasing, as well as small groups of squamous metaplastic cells.
  
  
  CONCLUSIONS
  FNAB is considered to be a rapid, bloodless and reliable method for the diagnosis of ameloblastoma. The cytology of these tumors reveals components of the lesion that, in general, are sufficient for the diagnosis of ameloblastoma, especially in cases of recurrence.
authors.affiliation: Hospital Universitario La Fe, Valencia.
authors.forename: M J
authors.initials: MJ
authors.lastname: Artes-Martínez
authors.forename: M
authors.initials: M
authors.lastname: Prieto-Rodríguez
authors.forename: M
authors.initials: M
authors.lastname: Navarro-Hervás
authors.forename: L
authors.initials: L
authors.lastname: Peñas-Pardo
authors.forename: A
authors.initials: A
authors.lastname: Camañas-Sanz
authors.forename: M C
authors.initials: MC
authors.lastname: Vaquero de la Hermosa
authors.forename: F J
authors.initials: FJ
authors.lastname: Vera-Sempere
mesh_terms: D000328:Adult; D000564:Ameloblastoma / Q000473:pathology*; D044963:Biopsy, Fine-Needle; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis