title: Deprotonation-electrophile trapping of terminal epoxides.
abstract: Organolithium-induced deprotonation of terminal epoxides in the presence of appropriate diamine ligands allows trapping with a range of electrophiles, yielding functionalised di- and tri-substituted epoxides in good yields and with control of stereochemistry at the epoxide.
authors.affiliation: Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, UKOX1 3TA.
authors.forename: David M
authors.initials: DM
authors.lastname: Hodgson
authors.forename: Eirene H M
authors.initials: EH
authors.lastname: Kirton
authors.forename: Steven M
authors.initials: SM
authors.lastname: Miles
authors.forename: Stéphanie L M
authors.initials: SL
authors.lastname: Norsikian
authors.forename: Nigel J
authors.initials: NJ
authors.lastname: Reynolds
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Coote
mesh_terms: D004852:Epoxy Compounds / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011522:Protons; D013055:Spectrophotometry, Infrared
chemical_list: D004852:Epoxy Compounds; D011522:Protons