title: Endophthalmitis following cataract surgery in southwest Finland from 1987 to 2000.
abstract: OBJECTIVE
  To investigate the incidence, causes, prevention, treatment and outcome of postoperative endophthalmitis (POE) following cataract surgery in southwest Finland from 1987 to 2000.
  
  
  METHODS
  We reviewed the medical records of all patients with POE following cataract surgery treated in the hospital district of Southwest Finland from 1 January 1987 to 31 December 2000. Population-based annual incidence rates of cataract extractions and POE were calculated using the corrected population statistics of the hospital district.
  
  
  RESULTS
  There were 29,350 cataract procedures during the 14-year period. POE developed in 47 patients. The annual incidence of cataract operations increased more than fivefold from 1987 (155 per 100,000 population) to the maximum in 1999 (930 per 100,000 population), whereas the annual incidence of postcataract endophthalmitis decreased from the maximum of 11.1 per 1,000 cataract extractions (1.91 per 100,000 population) in 1988 to the minimum of 0-0.6 per 1,000 cataract extractions in 1999 and 2000. POE occurred statistically significantly more frequently after extracapsular cataract extraction (ECCE) than after phacoemulsification (Phaco) (P=0.0006). Gram-positive bacteria were the most frequent cause of acute POE and Propionibacterium acnes was the most frequent reason for delayed-onset POE. The complications of POE after cataract surgery included visual loss to below 0.05 (25.5% of affected eyes), opacification of the cornea (21.3%), secondary cataract (40.4%), increase in intraocular pressure (29.8%), vitreous clouding (63.8%), and retinal detachment (6.4%). Nearly one half of the eyes achieved final visual acuity of 0.5 or better.
  
  
  CONCLUSIONS
  During the 14-year study period there was a shift from ECCE to Phaco, a fivefold increase in cataract extractions, and a decrease in the annual incidence of POE from 5.5-11.1 to 0-0.6 per 1,000 operations. Phaco was associated with a lower risk of POE than ECCE.
authors.affiliation: Department of Ophthalmology, University of Turku, 20520, Turku, Finland.
authors.forename: Timo T
authors.initials: TT
authors.lastname: Haapala
authors.forename: Laura
authors.initials: L
authors.lastname: Nelimarkka
authors.forename: Jukka M
authors.initials: JM
authors.lastname: Saari
authors.forename: Virpi
authors.initials: V
authors.lastname: Ahola
authors.forename: K Matti
authors.initials: KM
authors.lastname: Saari
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction / Q000009:adverse effects*; D009877:Endophthalmitis / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012307:Risk Factors; D017678:Sex Distribution