title: [Functional and morphological study of the local and systemic hypothermia on dog's liver].
abstract: OBJECTIVE
  To compare hepatic lesions produced by two types of hypothermia; the systemic and the local or topic.
  
  
  METHODS
  Twenty dogs distributed in two groups were studied: the first submitted to local hypothermia and the second to systemic hypothermia. In all groups, biochemical dosages for alanina allytransferase (A.L.T.), aspartate aminotrasnferase (A.S.T.) and direct bilirubin (T.D.), conventional optical microscopy and electronic transmission microscopy were performed in times T0, Test, and T60, that is, before the hypothermia (T0), after temperature stabilization at 10 degrees lower than initial temperature (Test), and after sixty minutes of hypothermia (T60).
  
  
  RESULTS
  The data analysis, both of the biochemical profile and of the microscopy showed that in the group of animals with selective hypothermia, the hepatic lesions were more intense when compared to the systemic hypothermia group.
  
  
  CONCLUSIONS
  The selective hypothermia causes more lesions to the liver than the systemic.
authors.affiliation: Disciplina de Técnica Operatória e Cirurgia Experimental Universidade Federal de São Paulo--Escola Paulista de Medicina.
authors.forename: Venilton José
authors.initials: VJ
authors.lastname: Siqueira
authors.forename: Murched Omar
authors.initials: MO
authors.lastname: Taha
authors.forename: Djalma José
authors.initials: DJ
authors.lastname: Fagundes
authors.forename: Paulo de Oliveira
authors.initials: Pde O
authors.lastname: Gomes
authors.forename: Yara
authors.initials: Y
authors.lastname: Juliano
authors.forename: Renata Marcon zanelatto
authors.initials: RM
authors.lastname: Bruzzadelli
authors.forename: Lucélia Rita Galdino
authors.initials: LR
authors.lastname: Caputto
mesh_terms: D000818:Animals; D004285:Dogs; D007036:Hypothermia, Induced / Q000009:adverse effects* / Q000379:methods; D008099:Liver / Q000473:pathology* / Q000503:physiopathology*