The cardiovascular burden of the dialysis patient: the impact of dialysis technology.
There is widespread recognition that the poor survival rates of dialysis patients, attributed predominantly to cardiovascular disease, need to be addressed and improved. In this paper, we relate diverse aspects of modern dialysis technology with factors that are considered to contribute towards increased mortality and morbidity in the dialysis population. Firstly, we assess the overall cardiovascular burden of the dialysis patient: it is the sum of uraemia-related risk factors (URRF), traditional risk factors and dialysis-therapy-related factors. Secondly, we describe how key components of the dialysis procedure may be directly related to the more common URRF: the dialyser and the membrane, microbiological quality of water and dialysate, treatment modality and online monitory equipment. The judicious selection and application of these components may collectively help improve patient outcomes in hemodialysis therapy.
Bowry
Sudhir K
SK
Fresenius Medical Care, Scientific Affairs, Bad Homburg, Germany.
Kuchinke-Kiehn
Ute
U
Ronco
Claudio
C
D002318:Cardiovascular Diseases / Q000209:etiology*; D004867:Equipment Design; D006801:Humans; D008991:Monitoring, Physiologic / Q000295:instrumentation; D006435:Renal Dialysis / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods*; D018570:Risk Assessment