A case of multiple cerebral abscesses due to infection with Cladophialophora bantiana.
Cladophialophora bantiana is a highly neurotropic fungus which has been reported to cause a variety of infections in the immunocompromised and transplant populations. We describe a case of multiple cerebral abscesses caused by this dematiaceous fungus in a patient with probable Duncan's syndrome. The patient also had extensive extra-cerebral disease, which is unusual for infection with this organism. We discuss previously described cases of infection with Cladophialophora bantiana, and review the current and evolving treatment options.
Roche
M
M
Department of Medical Microbiology, Beaumont Hospital, Dublin 9, Ireland. muireannroche@yahoo.com
Redmond
R Mac
RM
O'Neill
S
S
Smyth
E
E
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D001203:Ascomycota / Q000302:isolation & purification*; D001706:Biopsy; D001921:Brain / Q000473:pathology; D001922:Brain Abscess / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D020314:Central Nervous System Fungal Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D002963:Cladosporium / Q000302:isolation & purification*; D017809:Fatal Outcome; D006801:Humans; D016867:Immunocompromised Host; D020300:Intracranial Hemorrhages / Q000209:etiology; D008232:Lymphoproliferative Disorders / Q000150:complications; D008279:Magnetic Resonance Imaging; D008297:Male; D009164:Mycobacterium Infections / Q000150:complications / Q000188:drug therapy; D012008:Recurrence; D014057:Tomography, X-Ray Computed
D000935:Antifungal Agents; D000995:Antitubercular Agents