[Intensity of the production of rheumatoid factor in patients with different degrees of sensitization to Borrelia garinii antigens].
The content of rheumatoid factor and the levels of IgA, IgM, IgG in patients with different degrees of sensitization to Borrelia garinii antigens were studied. The titer of rheumatoid factor was found to increase in accordance with the growth of the levels of anti-Borrelia antibodies. A rise in the concentration of serum immunoglobulins simultaneously with the development of Borrelia infection was registered. The mechanisms of autoimmunization are discussed, taking into account the known biological properties of the causative agent of Lyme disease.
Kologrivova
E N
EN
Baraulina
A S
AS
Nechaeva
S V
SV
Shestakova
I I
II
Stronin
O V
OV
Vlasova
N M
NM
Sal'nikova
O M
OM
D000328:Adult; D000907:Antibodies, Bacterial / Q000096:biosynthesis / Q000097:blood*; D015551:Autoimmunity; D015748:Borrelia burgdorferi Group / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008193:Lyme Disease / Q000097:blood / Q000276:immunology*; D008875:Middle Aged; D012217:Rheumatoid Factor / Q000096:biosynthesis / Q000097:blood*
D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012217:Rheumatoid Factor