DNA mismatch detection using a pyrene-excimer-forming probe.
A pyrene-excimer-forming probe allowed the easy and sensitive detection of a single base mismatch in target DNA. This was due to the faster strand exchange rate compared to a fully-matched target.
Yamana
Kazushige
K
Department of Materials Science and Chemistry, University of Hyogo, 2167 Shosha, Himeji, Hyogo 671-2201, Japan. yamana@eng.u-hyogo.ac.jp
Fukunaga
Yudai
Y
Ohtani
Yusuke
Y
Sato
Sayaka
S
Nakamura
Mitsunobu
M
Kim
Won Jong
WJ
Akaike
Toshihiro
T
Maruyama
Atsushi
A
D020137:Base Pair Mismatch; D004247:DNA / Q000737:chemistry* / Q000235:genetics; D004252:DNA Mutational Analysis / Q000379:methods; D011721:Pyrenes / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013816:Thermodynamics
D011721:Pyrenes; D004247:DNA