Enantioselective allylation of aldehydes catalyzed by chiral indium(III) complexes immobilized in ionic liquids.
In the presence of chiral catalytic complexes prepared from In(OTf)3 and chiral PYBOX ligands, allytributylstannane reacted with aldehydes in ionic liquids to afford the corresponding homoallylic alcohols in high enantioselectivities (86-94% ee) and good yields (68-89%); the chiral catalysts immobilized in ionic liquids could be reused with comparable enantioselectivities and yields.
Lu
Jun
J
Key Lab. of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering of Suzhou University, Suzhou, 215006, China. shunjun@suda.edu.cn
Ji
Shun-Jun
SJ
Loh
Teck-Peng
TP
D000438:Alcohols / Q000138:chemical synthesis*; D000447:Aldehydes / Q000138:chemical synthesis* / Q000737:chemistry; D000478:Alkylation; D002384:Catalysis; D007204:Indium / Q000737:chemistry*; D052578:Ionic Liquids / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D009947:Organotin Compounds / Q000737:chemistry; D013237:Stereoisomerism
D000438:Alcohols; D000447:Aldehydes; D052578:Ionic Liquids; D009942:Organometallic Compounds; D009947:Organotin Compounds; D007204:Indium