title: [Pre-implantation genetic diagnosis and spontaneous pregnancies: an unexpected acting out].
abstract: OBJECTIVE
  To understand the psychological motives that led these couples to take risks involved in genetic transmission and the possibility of another spontaneous pregnancy. To report our psychoanalytic experience to explain why after a request of pre-implantation genetic diagnosis (PGD), some women prefer to be spontaneously pregnant.
  
  
  METHODS
  Between 2000 and 2004, out of 643 requests of PGD, 541 have been admitted, among which 123 spontaneous pregnancies appeared during the process of PGD.
  
  
  RESULTS
  Some encounters with the patients have shown some reasons to these spontaneous pregnancies - denial of IVF, ambivalence of this desire for a child, denial of the risk, control of the procreation, family loyalty and fertility affirmation.
  
  
  CONCLUSIONS
  The resort to PGD is more ambivalent than the thought of it because it means, beyond the request, conflict with transmission, culture, and history origins.
authors.affiliation: Service de gynécologie-obstétrique et médecine de la reproduction, hôpital Antoine-Béclère (AP-HP), 157, rue de la Porte-de-Trivaux, 92141 Clamart, France. mflis@club-internet.fr
authors.forename: M
authors.initials: M
authors.lastname: Flis-Trèves
authors.forename: N
authors.initials: N
authors.lastname: Frydman
authors.forename: R
authors.initials: R
authors.lastname: Frydman
authors.forename: V
authors.initials: V
authors.lastname: Kerbrat
authors.forename: A
authors.initials: A
authors.lastname: Munnich
authors.forename: M
authors.initials: M
authors.lastname: Vekemans
mesh_terms: D005260:Female; D030342:Genetic Diseases, Inborn / Q000175:diagnosis* / Q000235:genetics*; D006801:Humans; D008297:Male; D011247:Pregnancy; D019836:Preimplantation Diagnosis / Q000523:psychology*; D012307:Risk Factors