title: Preventive treatment of headaches.
abstract: OBJECTIVE
  To review recent advances in preventive headache treatment.
  
  
  RESULTS
  Migraine may be a progressive disorder. Aggressive treatment may stop progression. Propranolol, the beta-blocker, and the anticonvulsant topiramate are effective for migraine prevention. Feverfew, montelukast and acupuncture have not proven effective.
  
  
  CONCLUSIONS
  New drugs and other treatment strategies expand the spectrum of preventive migraine treatments.
authors.affiliation: Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA. Stephen.Silberstein@jefferson.edu
authors.forename: Stephen D
authors.initials: SD
authors.lastname: Silberstein
mesh_terms: D015670:Acupuncture Therapy / Q000379:methods; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D018450:Disease Progression; D005632:Fructose / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008881:Migraine Disorders / Q000517:prevention & control*; D011433:Propranolol / Q000627:therapeutic use; D000077236:Topiramate
chemical_list: D000319:Adrenergic beta-Antagonists; D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose; D011433:Propranolol