Impact of assisted hatching on ART outcome in women with endometriosis.
BACKGROUND
Assisted hatching can improve the implantation rate in cycles with poor outcome. The impact of assisted hatching in embryos from women with endometriosis is not known. Therefore, the hypothesis that the implantation potential of embryos obtained from women with endometriosis can be improved with assisted hatching was tested.


METHODS
In a prospective randomized study, transfer embryos obtained from 60 women with endometriosis were hatched using a laser system and compared to embryos obtained from patients with the same diagnosis which were left intact (n = 30).


RESULTS
The characteristics of cycles were similar between groups. The pregnancy (40% zona intact, 28.3% assisted hatching), and implantation rates (19.4% zona intact, 17.8% assisted hatching) did not differ in endometriosis cycles regardless of assisted hatching.


CONCLUSIONS
Assisted hatching does not improve outcome in women with endometriosis undergoing assisted reproduction.
Nadir Ciray
H
H
Bahceci Women Health Care Centre and German Hospital at Istanbul, Istanbul, Turkey.
Bener
Faruk
F
Karagenç
Levent
L
Ulug
Ulun
U
Bahçeci
Mustafa
M
D000328:Adult; D010064:Embryo Implantation; D004715:Endometriosis / Q000150:complications*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011446:Prospective Studies; D027724:Reproductive Techniques, Assisted; D015044:Zona Pellucida