title: [Exercise-induced left arm pain and thrombocytosis].
abstract: We describe the case of a 45-year-old male smoker who presented with an acute anterior wall myocardial infarction and a platelet count on admission of 1030000/mm3. Emergent coronary angiography revealead left anterior wall akinesia caused by a spontaneously resolved thrombosis of the left anterior descending artery with residual stenosis. Primary percutaneous coronary angioplasty and stenting were performed. Postangioplasty course was uneventful. He was diagnosed with essential thrombocythemia based on the findings of marked thrombocytosis of 1,030,000/mm3, splenomegaly and numerous clumping giant megakaryocytes on bone marrow biopsy. In addition to standard therapy with aspirin, heparin, betablocking agent, ACE-inhibitor and statine he received additional anti-platelet therapy with Clopidogrel. Cytoreductive therapy was not necessary.
authors.affiliation: Departement Innere Medizin, Universitätsspital Zürich.
authors.forename: I
authors.initials: I
authors.lastname: Kunz
authors.forename: S
authors.initials: S
authors.lastname: Spada
authors.forename: G
authors.initials: G
authors.lastname: Sütsch
authors.forename: F
authors.initials: F
authors.lastname: Ruggieri
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D001856:Bone Marrow Examination; D000077144:Clopidogrel; D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000628:therapy*; D023921:Coronary Stenosis / Q000175:diagnosis / Q000000981:diagnostic imaging; D003328:Coronary Thrombosis / Q000175:diagnosis / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D010976:Platelet Count; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D015607:Stents; D013920:Thrombocythemia, Essential / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D013988:Ticlopidine / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine