title: Usefulness of plasma brain-type natriuretic peptide level to differentiate left ventricular diastolic dysfunction from preserved diastolic function in patients with systolic dysfunction.
abstract: The extent of left ventricular (LV) diastolic dysfunction is related to the finding that some patients with cardiomegaly due to LV systolic dysfunction have good exercise tolerance, although others have limited tolerance. A brain-type natriuretic peptide level of >/=104 pg/ml reliably enables the detection of relatively worse LV diastolic function in patients with systolic dysfunction, and this value may provide clinically useful information for the management of patients with cardiomegaly.
authors.affiliation: Department of Internal Medicine and Pathophysiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Goto
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Ohte
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Miyabe
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Sakata
authors.forename: Kaoru
authors.initials: K
authors.lastname: Asada
authors.forename: Seiji
authors.initials: S
authors.lastname: Mukai
authors.forename: Junichiro
authors.initials: J
authors.lastname: Hayano
authors.forename: Genjiro
authors.initials: G
authors.lastname: Kimura
mesh_terms: D015415:Biomarkers / Q000097:blood*; D006332:Cardiomegaly / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D013599:Systole; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis*
chemical_list: D015415:Biomarkers; D020097:Natriuretic Peptide, Brain