title: Personalized medical treatment strategies for patients with chronic myeloid leukemia.
abstract: Management of patients with chronic myeloid leukemia has become increasingly difficult over the last few years since there are a variety of treatment options available. The ultimate challenge is to decide the most appropriate treatment strategy for an individual patient. To facilitate this, assessment of an individual patient's disease in terms of status, tempo and response to initial treatment needs to be determined. This review article discusses the current treatment options in the management of chronic myeloid leukemia, the factors that influence management decisions and suggests how treatment for the individual patient may be tailored whilst involving the patient in the decision-making process.
authors.affiliation: Imperial College School of Medicine, Department of Haematology, Hammersmith Hospital, Du Cane Road, London W12 ONN, UK. cb@ctc.ucl.ac.uk
authors.forename: Catherine
authors.initials: C
authors.lastname: Burton
authors.forename: David
authors.initials: D
authors.lastname: Marin
authors.forename: Jane
authors.initials: J
authors.lastname: Apperley
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016026:Bone Marrow Transplantation; D003657:Decision Making; D006680:HLA Antigens; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000628:therapy*; D009367:Neoplasm Staging; D010347:Patient Care Planning; D011379:Prognosis; D018570:Risk Assessment; D014184:Transplantation, Homologous
chemical_list: D006680:HLA Antigens