title: Impact of assisted hatching on ART outcome in women with endometriosis.
abstract: BACKGROUND
  Assisted hatching can improve the implantation rate in cycles with poor outcome. The impact of assisted hatching in embryos from women with endometriosis is not known. Therefore, the hypothesis that the implantation potential of embryos obtained from women with endometriosis can be improved with assisted hatching was tested.
  
  
  METHODS
  In a prospective randomized study, transfer embryos obtained from 60 women with endometriosis were hatched using a laser system and compared to embryos obtained from patients with the same diagnosis which were left intact (n = 30).
  
  
  RESULTS
  The characteristics of cycles were similar between groups. The pregnancy (40% zona intact, 28.3% assisted hatching), and implantation rates (19.4% zona intact, 17.8% assisted hatching) did not differ in endometriosis cycles regardless of assisted hatching.
  
  
  CONCLUSIONS
  Assisted hatching does not improve outcome in women with endometriosis undergoing assisted reproduction.
authors.affiliation: Bahceci Women Health Care Centre and German Hospital at Istanbul, Istanbul, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Nadir Ciray
authors.forename: Faruk
authors.initials: F
authors.lastname: Bener
authors.forename: Levent
authors.initials: L
authors.lastname: Karagenç
authors.forename: Ulun
authors.initials: U
authors.lastname: Ulug
authors.forename: Mustafa
authors.initials: M
authors.lastname: Bahçeci
mesh_terms: D000328:Adult; D010064:Embryo Implantation; D004715:Endometriosis / Q000150:complications*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011446:Prospective Studies; D027724:Reproductive Techniques, Assisted; D015044:Zona Pellucida