title: Nocardiosis in a teaching hospital in the Central Anatolia region of Turkey: treatment and outcome.
abstract: Predisposing factors, antimicrobial susceptibility patterns, treatment and outcome were analysed for nine consecutive patients with nocardiosis. Predisposing factors were identified in six (67%) of the nine patients. Clinical syndromes of nocardial infection were pulmonary infection (three patients), cerebral infection (five patients) and disseminated infection (one patient). The predominant (60%) species was Nocardia farcinica rather than the Nocardia asteroides complex. Treatment was started empirically, modified according to the antimicrobial susceptibility pattern, and then continued for 6-12 months. Overall mortality was 33%, with death being caused by the Nocardia infection in two cases.
authors.affiliation: Infectious Diseases, Medical Faculty, Erciyes University, Kayseri, Turkey. oyildiz@erciyes.edu.tr
authors.forename: O
authors.initials: O
authors.lastname: Yildiz
authors.forename: E
authors.initials: E
authors.lastname: Alp
authors.forename: B
authors.initials: B
authors.lastname: Tokgoz
authors.forename: B
authors.initials: B
authors.lastname: Tucer
authors.forename: B
authors.initials: B
authors.lastname: Aygen
authors.forename: B
authors.initials: B
authors.lastname: Sumerkan
authors.forename: A
authors.initials: A
authors.lastname: Couble
authors.forename: P
authors.initials: P
authors.lastname: Boiron
authors.forename: M
authors.initials: M
authors.lastname: Doganay
mesh_terms: D000328:Adult; D000583:Amikacin / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001922:Brain Abscess / Q000473:pathology / Q000601:surgery; D015984:Causality; D002443:Ceftriaxone / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D015378:Imipenem / Q000494:pharmacology; D008171:Lung Diseases / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008826:Microbial Sensitivity Tests; D009615:Nocardia / Q000187:drug effects / Q000302:isolation & purification*; D009617:Nocardia Infections / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D012189:Retrospective Studies; D014421:Turkey / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents; D015378:Imipenem; D002443:Ceftriaxone; D000583:Amikacin