Prenatal diagnosis of 47,XXX.
We report 2 cases of 47,XXX that were diagnosed prenatally and were screened positive for trisomy 21 by biochemical and ultrasound markers. These cases underline the importance of discussing the sex chromosome abnormalities during the genetic counseling after an abnormal triple screen test or ultrasound examination.
Khoury-Collado
Fady
F
Department of Obstetrics and Gynecology, Lutheran Medical Center, Brooklyn, NY, USA. dfakc25@hotmail.com
Wehbeh
Ammar N
AN
Fisher
Allan J
AJ
Bombard
Allan T
AT
Weiner
Zeev
Z
D000328:Adult; D000649:Amniocentesis; D041321:Chromosomes, Human, X; D004314:Down Syndrome / Q000175:diagnosis; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D011247:Pregnancy; D011272:Pregnancy, Multiple; D011296:Prenatal Diagnosis; D014314:Trisomy; D014427:Twins