Synthesis of mixed esters of ascorbic acid using methyl esters of palm and soybean oils.
Mixed esters of ascorbic acid were synthesized using methyl esters of palm and soybean oils as acyl donors, in acetone at 50 degrees C, and catalyzed by Novozym 435. A conversion of 62% was obtained with palm oil methyl ester at an ascorbic acid to acyl donor molar ratio of 1:4; the mixed ester contained 45.89% ascorbyl palmitate, 42.59% ascorbyl oleate and 10.1% ascorbyl linoleate. Acylation with soybean oil methyl ester resulted in 17% conversion, yielding a mixed ester containing 10.08% ascorbyl palmitate, 20.68% ascorbyl oleate, and 64.96% of ascorbyl linoleate. The mixed esters of ascorbic acid can find direct use in food and cosmetics.
Hsieh
Hsin-Ju
HJ
Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan.
Chen
Jech-Wei
JW
Giridhar
R
R
Wu
Wen-Teng
WT
D001205:Ascorbic Acid / Q000138:chemical synthesis*; D004800:Enzymes, Immobilized; D004952:Esters / Q000138:chemical synthesis; D005240:Feasibility Studies; D005656:Fungal Proteins; D008049:Lipase / Q000737:chemistry*; D008745:Methylation; D000073878:Palm Oil; D010938:Plant Oils / Q000737:chemistry*; D013024:Soybean Oil / Q000737:chemistry*; D013379:Substrate Specificity
D004800:Enzymes, Immobilized; D004952:Esters; D005656:Fungal Proteins; D010938:Plant Oils; D000073878:Palm Oil; D013024:Soybean Oil; C093667:Novozyme 435; D008049:Lipase; D001205:Ascorbic Acid