Reconstructive surgery of male urethra using human amnion membranes (grafts)--first announcement.
OBJECTIVE
Assessment of technical aspects of the surgical procedure and usefulness, suitability and efficacy of human amnion grafts as a biomaterial in reconstructive surgery of strictured male urethra.


METHODS
Human amnion membranes were used in 2 men suffering from long, recurring strictures of urethra. Narrowed part of urethra was careful prepared and cleaned of adjacent tissue. Then a longitudinal incision was performed through the whole length of strictured segment and then it was covered with human amnion membrane.


RESULTS
Hospitalization time 4 to 5 days. The Foley catheter was removed 2 weeks after surgery 3 months after surgery controlled urethrographies and urethroscopies show wide urethra lumen, wider than in adjacent parts. In urethroscopy operated place covered with epithelium, smooth, without scare.


CONCLUSIONS
Human amnion grafts and described technique seem to be a promising method of managing long, recurring male urethra strictures but need long-term follow-up and analysis of more cases.
Koziak
Andrzej
A
Departament of Urology, Specialised Regional Hospital Hospital in Siedlce, Poland. urologiasiedlce@wp.pl
Marcheluk
Adam
A
Dmowski
Tadeusz
T
Szcześniewski
Ryszard
R
Kania
Piotr
P
Dorobek
Adam
A
D000650:Amnion / Q000637:transplantation*; D001672:Biocompatible Materials; D006801:Humans; D008297:Male; D011859:Radiography; D019651:Plastic Surgery Procedures / Q000379:methods*; D014521:Urethra / Q000601:surgery*; D014525:Urethral Stricture / Q000000981:diagnostic imaging / Q000601:surgery*
D001672:Biocompatible Materials