title: Lipophilic flavones of Primula veris L. from field cultivation and in vitro cultures.
abstract: Ten lipophilic flavones were isolated from the leaves of Primula veris from field cultivation - the newly described 3'-hydroxy-4',5'-dimethoxyflavone and 3'-methoxy-4',5'-methylenedioxyflavone, the previously known from chemical synthesis 3',4'-dimethoxyflavone, 2',5'-dimethoxyflavone, and also flavone, 2'-hydroxyflavone, 2'-methoxyflavone, 3'-methoxyflavone, 3',4',5'-trimethoxyflavone and 5,6,2',6'-tetramethoxyflavone (zapotin) which were previously known from plants. The same flavones were found in the leaves of P. veris obtained by in vitro propagation. The structural assignments were derived from (1)H NMR, (13)C NMR, EIMS and UV spectral data and the influence of B-ring oxygen substituents on the C-2, C-3 and H-3 NMR resonances in flavones unsubstituted in the A ring is taken into consideration.
authors.affiliation: Department of Pharmaceutical Botany, K. Marcinkowski University of Medical Sciences, 14 Sw. Marii Magdaleny Str., 61-861 Poznań, Poland. jbudzian@amp.edu.pl
authors.forename: Jaromir
authors.initials: J
authors.lastname: Budzianowski
authors.forename: Maria
authors.initials: M
authors.lastname: Morozowska
authors.forename: Maria
authors.initials: M
authors.lastname: Wesołowska
mesh_terms: D047309:Flavones / Q000737:chemistry* / Q000302:isolation & purification; D015394:Molecular Structure; D031825:Primula / Q000737:chemistry* / Q000254:growth & development
chemical_list: D047309:Flavones