[Clinical and immunological effect produced by vaccination with "Pneumo 23" of children with atopic bronchial asthma].
A total of 45 children aged 4-16 years with atopic bronchial asthma of different severity level-resulted from a past case of outhospital pneumonia, received vaccine "Pneumo 23" ("Aventis Pasteur", France). The vaccine was found to be well tolerated, no cases of the exacerbation of the atopic process were registered. A reliable Increased level of specific antibodies to the mixture of polysaccharides, contained in the vaccine "Pneumo 23", was found to occur. The tendency towards decreased level of serum IgE was established.
Markelova
E V
EV
Gushchina
Ia S
IaS
Kostinov
M P
MP
Zhuravleva
N V
NV
D000293:Adolescent; D000907:Antibodies, Bacterial / Q000097:blood; D001249:Asthma / Q000097:blood / Q000150:complications / Q000276:immunology*; D002648:Child; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000097:blood / Q000150:complications / Q000276:immunology*; D011008:Pneumococcal Infections / Q000150:complications / Q000517:prevention & control*; D022242:Pneumococcal Vaccines / Q000008:administration & dosage*; D011135:Polysaccharides, Bacterial / Q000008:administration & dosage*; D014611:Vaccination
C414006:23-valent pneumococcal capsular polysaccharide vaccine; D000907:Antibodies, Bacterial; D022242:Pneumococcal Vaccines; D011135:Polysaccharides, Bacterial