title: Photoprotective activity of Buddleja scordioides.
abstract: The purpose of this study was to determine the photoprotective properties of the methanolic extract of Buddleja scordioides, as well as verbascoside and linarin which were isolated from this extract, and linarin acetate prepared in the laboratory. The photoprotective effect of substances against UV-B induced cellular death was evaluated by challenge experiments using Escherichia coli. Verbascoside and linarin acetate showed the highest protection. The sun protection factor (SPF) of the methanolic extract, linarin, linarin acetate, and verbascoside was evaluated by guinea pig bioassays. Verbascoside showed the largest SPF measurement.
authors.affiliation: Laboratorio de Fitoquímica, Unidad de Biología, Tecnología y Prototipos (UBIPRO), Universidad Nacional Autónoma de México, FES Iztacala, Tlalnepantla, C. P. 54090, México. tuncomaclovio@correo.unam.mx
authors.forename: J G
authors.initials: JG
authors.lastname: Avila Acevedo
authors.forename: C M C
authors.initials: CM
authors.lastname: Castañeda
authors.forename: F J C
authors.initials: FJ
authors.lastname: Benitez
authors.forename: D A
authors.initials: DA
authors.lastname: Durán
authors.forename: V R
authors.initials: VR
authors.lastname: Barroso
authors.forename: C G
authors.initials: CG
authors.lastname: Martínez
authors.forename: L J L
authors.initials: LJ
authors.lastname: Muñoz
authors.forename: C A
authors.initials: CA
authors.lastname: Martínez
authors.forename: A
authors.initials: A
authors.lastname: Romo de Vivar
mesh_terms: D000818:Animals; D032861:Buddleja / Q000737:chemistry*; D004926:Escherichia coli / Q000528:radiation effects; D005260:Female; D005960:Glucosides / Q000737:chemistry / Q000494:pharmacology*; D006027:Glycosides / Q000737:chemistry / Q000494:pharmacology*; D006168:Guinea Pigs; D008297:Male; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry / Q000494:pharmacology*; D035261:Plant Components, Aerial / Q000737:chemistry; D013473:Sunscreening Agents / Q000494:pharmacology*; D013997:Time Factors; D014466:Ultraviolet Rays; D059808:Polyphenols
chemical_list: D005960:Glucosides; D006027:Glycosides; D010636:Phenols; D013473:Sunscreening Agents; C058956:acteoside; D059808:Polyphenols; C008282:linarin