Vogt-Koyanagi-Harada syndrome following injury-induced progressive vitiligo.
We report a case of Vogt-Koyanagi-Harada (VKH), Syndrome wherein the patient developed ocular symptoms following injury-induced progressive vitiligo with immunologic evidence from the skin biopsy specimen of the vitiligo. This case supports the hypothesis that the cell-mediated immune process against a common melanocyte antigen plays an important role in the development and progression of the disease.
Gupta
V
V
Department of Ophthalmology, I Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Gupta
A
A
Bambery
P
P
Radotra
B D
BD
Pandav
S S
SS
D000063:Accidents, Traffic; D001706:Biopsy; D016516:CD4-CD8 Ratio; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006230:Hand Injuries / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008875:Middle Aged; D009104:Multiple Trauma; D010857:Pigment Epithelium of Eye / Q000473:pathology; D011859:Radiography; D012867:Skin / Q000473:pathology; D014607:Uveomeningoencephalitic Syndrome / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D014820:Vitiligo / Q000150:complications* / Q000276:immunology / Q000473:pathology