The "pulvinar sign" in a case of paraneoplastic limbic encephalitis associated with non-Hodgkin's lymphoma.
This paper reports a 59 year old woman with paraneoplastic limbic encephalitis associated with diffuse large B cell lymphoma. Her brain magnetic resonance imaging scan showed bilateral posterior thalamic hyperintensities, similar to the "pulvinar sign". Her symptoms included progressive psychiatric disturbance and resembled the initial symptoms of variant Creutzfeldt-Jakob disease (vCJD). Clinicians should consider this treatable disorder in the differential diagnosis of vCJD.
Mihara
M
M
Department of Neurology, Osaka University Graduate School of Medicine,D-4, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan. m-mihara@neurol.med.osaka-u.ac.jp
Sugase
S
S
Konaka
K
K
Sugai
F
F
Sato
T
T
Yamamoto
Y
Y
Hirota
S
S
Sakai
K
K
Sakoda
S
S
D001365:Axilla; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006624:Hippocampus / Q000473:pathology; D006801:Humans; D020363:Limbic Encephalitis / Q000150:complications / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D020649:Pulvinar / Q000473:pathology*; D013702:Temporal Lobe / Q000473:pathology; D013788:Thalamus / Q000473:pathology