Heparin-induced thrombocytopenia--a potential iatrogenic complication for patients with cardiac and vascular disease.
Physicians involved in the care of patients with cardiac and vascular problems regularly employ heparin in treatment regimens of inpatients and outpatients. Heparin-induced thrombocytopenia is an important complication that can result in significant morbidity and mortality. It is reasonable, therefore, to review the pathogenetic mechanisms involved, the identification of heparin-induced thrombocytopenia, and the management to minimize morbidity and mortality.
Sanfelippo
Peter M
PM
Cardiovascular and Thoracic Surgery, University of Texas Health Center at Tyler, TX 75703, USA. petersanfelippo@aol.com
D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D007049:Iatrogenic Disease; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000628:therapy; D013927:Thrombosis / Q000139:chemically induced
D006493:Heparin