Cognitive recovery after delayed carbon monoxide encephalopathy.
We report on a patient with delayed carbon monoxide encephalopathy who presented with severe cognitive impairment associated with MRI findings of extensive demyelination of the cerebral white matter after a silent period of three weeks from acute intoxication. Despite the severe signs of structural and functional cerebral impairment in the sub-acute stage, the clinical course was favorable but for residual mild dysfunction of the frontal lobes.
Cocito
Leonardo
L
Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Via Antonio De Toni 5, I-16132 Genoa, Italy. lcocito@neurologia.unige.it
Biagioli
Manuela
M
Fontana
Paola
P
Inglese
Maria Laura
ML
Pizzorno
Matteo
M
Spigno
Fabio
F
Volpe
Silvia
S
D001927:Brain Diseases / Q000209:etiology* / Q000523:psychology*; D002249:Carbon Monoxide Poisoning / Q000150:complications*; D003072:Cognition Disorders / Q000209:etiology*; D005625:Frontal Lobe; D006801:Humans; D008297:Male; D008875:Middle Aged; D020127:Recovery of Function; D012720:Severity of Illness Index; D013997:Time Factors