title: Natural history of tumour-related sacral obliteration with nerve-root preservation.
abstract: Benign aggressive bone tumours can present a dilemma when the definitive treatment options necessitate enormous and permanent functional deficits. Here, we present a case of a massive sacral giant-cell tumour causing dramatic skeletal obliteration, which was successfully treated with radical radiotherapy rather than ablative surgery. The excellent functional outcome highlights the importance of nerve-root preservation in selecting treatment modalities.
authors.affiliation: Peter MacCallum Cancer Centre, Melbourne, Australia. s.hopyan@utoronto.ca
authors.forename: S
authors.initials: S
authors.lastname: Hopyan
authors.forename: S Y K
authors.initials: SY
authors.lastname: Ngan
authors.forename: P F M
authors.initials: PF
authors.lastname: Choong
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000503:physiopathology / Q000532:radiotherapy*; D018450:Disease Progression; D005260:Female; D018212:Giant Cell Tumor of Bone / Q000503:physiopathology / Q000532:radiotherapy*; D006801:Humans; D020127:Recovery of Function; D012447:Sacrum; D013126:Spinal Nerve Roots / Q000503:physiopathology