title: [Effect of terbinafine in treating onychomycosis in children: clinical observation of 88 cases].
abstract: OBJECTIVE
  To observe the therapeutic effect and safety of terbinafine in treating onychomycosis in children.
  
  
  METHODS
  Terbinafine was used to treat 50 children with fingernail onychomycosis and 38 with toenail onychomycosis, and the efficacy, fungal clearance and safety of the drug were evaluated.
  
  
  RESULTS
  The clinical cure rate and total effective rate were 92.1% and 97.37%, respectively, for fingernail onychomycosis, and 86.36% and 93.94% for toenail onychomycosis, with fungal clearance rate of 96.59%. No serious side-effects was observed in the children receiving terbinafine therapy.
  
  
  CONCLUSIONS
  Terbinafine is effective and safe for the treatment of onychomycosis in children.
authors.affiliation: Department of Dermatology, Second People's Hospital of Guangdong Province, Guangzhou 510317, China.
authors.forename: Ju
authors.initials: J
authors.lastname: Wen
authors.forename: Zhong-fang
authors.initials: ZF
authors.lastname: Lin
mesh_terms: D000293:Adolescent; D000935:Antifungal Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006229:Hand Dermatoses / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009281:Naphthalenes / Q000627:therapeutic use*; D014009:Onychomycosis / Q000188:drug therapy*; D000077291:Terbinafine
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine