title: Lack of correlation between total lymphocyte count and nutritional status in the elderly.
abstract: OBJECTIVE
  Malnutrition is a widespread but largely unrecognized problem in aged people. Although absolute total lymphocyte count (TLC) has been proposed as a useful indicator of nutritional status, there is little evidence that low TLC levels reflect malnutrition in the elderly. To examine whether TLC is a suitable marker of malnutrition in the elderly.
  
  
  METHODS
  A total of 161 elderly subjects (44 males and 117 females, mean age+/-SD: 77.9+/-7.4; range: 65-95 years) were enrolled from geriatric clinical settings. The participants were categorized according to severely low, low, or normal TLC. Anthropometry measurements, serum albumin, total cholesterol levels, and total score on the mini-nutritional assessment (MNA) were determined.
  
  
  RESULTS
  There were no significant differences among the three TLC groups with regard to anthropometry measurements, serum albumin, total cholesterol levels, or MNA score. There was a significant negative correlation of TLC with age, but not with other nutritional markers. The clinical nutritional screening tool, MNA score, was well correlated with all of the nutritional parameters used in the present study except for TLC.
  
  
  CONCLUSIONS
  TLC is not a suitable marker of malnutrition in the elderly.
authors.affiliation: Department of Geriatrics, Graduate School of Medicine, Nagoya University, 65 Tusruma-cho, Showa-ku, Nagoya 466-8550, Japan. kuzuya@med.Nagoya-u.ac.jp
authors.forename: Masafumi
authors.initials: M
authors.lastname: Kuzuya
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kanda
authors.forename: Teruhiko
authors.initials: T
authors.lastname: Koike
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Akihisa
authors.initials: A
authors.lastname: Iguchi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000886:Anthropometry; D002784:Cholesterol / Q000097:blood; D005260:Female; D006801:Humans; D018655:Lymphocyte Count; D008297:Male; D044342:Malnutrition / Q000097:blood* / Q000175:diagnosis; D015596:Nutrition Assessment; D009752:Nutritional Status; D012709:Serum Albumin / Q000378:metabolism; D018709:Statistics, Nonparametric
chemical_list: D012709:Serum Albumin; D002784:Cholesterol