Detection of nitroaromatic and cyclic nitramine compounds by cyclodextrin assisted capillary electrophoresis quadrupole ion trap mass spectrometry.
An Agilent 3DCE capillary electrophoresis system using sulfobutylether-beta-cyclodextrin (SB-beta-CD)-ammonium acetate separation buffer pH 6.9 was coupled to a Bruker Esquire 3000+ quadrupole ion trap mass detector via a commercially available electrospray ionization interface with acetonitrile sheath flow. The CE-MS system was applied in negative ionization mode for the resolution and detection of nitroaromatic and polar cyclic or caged nitramine energetic materials including TNT [2,4,6-trinitrotoluene, formula mass (FW) 227.13], TNB (1,3,5-trinitrobenzene, FW 213.12), RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine, FW 222.26) HMX (octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine, FW 296.16), and CL-20 (2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane, FW 438.19). The CE-MS system conformed to the high-performance liquid chromatography with ultraviolet absorbance detection (HPLC-UV) and HPLC-MS reference methods for the identification of energetic contaminants and their degradation products in soil and marine sediment samples.
Groom
Carl A
CA
Biotechnology Research Institute, National Research Council of Canada, 6100 Royalmount Avenue, Montreal, Canada PQ H4P 2R2.
Halasz
Annamaria
A
Paquet
Louise
L
Thiboutot
Sonia
S
Ampleman
Guy
G
Hawari
Jalal
J
D001372:Aza Compounds / Q000032:analysis; D001392:Azocines / Q000032:analysis; D019075:Electrophoresis, Capillary / Q000379:methods*; D004785:Environmental Pollutants / Q000032:analysis*; D019015:Geologic Sediments / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000032:analysis; D006573:Heterocyclic Compounds, 1-Ring / Q000032:analysis; D009574:Nitro Compounds / Q000032:analysis*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D014227:Triazines / Q000032:analysis; D014301:Trinitrobenzenes / Q000032:analysis; D014303:Trinitrotoluene / Q000032:analysis; D047392:beta-Cyclodextrins
C482139:2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaaza-isowurtzitane; D001372:Aza Compounds; D001392:Azocines; D004785:Environmental Pollutants; D006571:Heterocyclic Compounds; D006573:Heterocyclic Compounds, 1-Ring; D009574:Nitro Compounds; D014227:Triazines; D014301:Trinitrobenzenes; D047392:beta-Cyclodextrins; D014303:Trinitrotoluene; C029222:sym-trinitrobenzene; C093196:SBE4-beta-cyclodextrin; C007950:octogen; C009160:cyclonite