[Advances of the coatings used in columns for capillary electrophoresis and in nanochannels of chips].
An overview is provided on the advancement and development of coating preparation methodology and materials used in capillaries and channels in microfluidic chip. Discussion is also given on the effects of coatings in the resolutions of separation and the reproducibility of separations. Dynamic coatings and linked coatings, classified as homo-polymers, copolymers and heterocyclic compounds, are further discussed, and so are the methods for the preparation of the coatings by cross-linked reaction, sol-gel process, photomodification and chemical deposition, etc. The discussion will be useful for the optimization of capillary columns that are used in capillary electrophoresis and nanochannels of chip.
Liu
Chunye
C
School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China. doris8976@163.com
Chen
Jierong
J
D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods; D019075:Electrophoresis, Capillary / Q000295:instrumentation* / Q000379:methods; D046209:Electrophoresis, Microchip / Q000295:instrumentation / Q000379:methods*; D007202:Indicators and Reagents; D044085:Microfluidics / Q000379:methods; D049329:Nanostructures; D036103:Nanotechnology / Q000379:methods; D011108:Polymers / Q000032:analysis*
D020099:Coated Materials, Biocompatible; D007202:Indicators and Reagents; D011108:Polymers