title: Analgesic activity of the roots and leaves extracts of Calliandra portoricensis.
abstract: The analgesic activity of the methanolic extracts of the roots and leaves of Calliandra portoricensis was investigated in mice and rats using acetic acid-induced writhing and formalin tests. The extracts given orally at the doses of 200, 400, 600 mg/kg showed a dose-dependent activity in the tests used.
authors.affiliation: Department of Pharmacognosy and Drug Development, Ahmadu Bello University, Zaria, Nigeria. agunua@yahoo.com
authors.forename: Abdulkarim
authors.initials: A
authors.lastname: Agunu
authors.forename: E M
authors.initials: EM
authors.lastname: Abdurahman
authors.forename: M
authors.initials: M
authors.lastname: Shok
authors.forename: Sadiq A
authors.initials: SA
authors.lastname: Yusuf
mesh_terms: D019342:Acetic Acid; D000284:Administration, Oral; D000700:Analgesics / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D004305:Dose-Response Relationship, Drug; D007887:Fabaceae; D005557:Formaldehyde; D008297:Male; D051379:Mice; D010146:Pain / Q000139:chemically induced / Q000517:prevention & control*; D010147:Pain Measurement / Q000187:drug effects; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D018517:Plant Roots; D051381:Rats
chemical_list: D000700:Analgesics; D010936:Plant Extracts; D005557:Formaldehyde; D019342:Acetic Acid