title: Factors affecting the long-term patency of crossover femorofemoral bypass graft.
abstract: OBJECTIVE
  To determine the factors affecting long-term patency of crossover femorofemoral bypass (FFB) graft.
  
  
  METHODS
  A retrospective clinical study of a prospectively registered database.
  
  
  METHODS
  Two hundred and sixteen FFBs performed for 192 patients with atherosclerotic iliac occlusive disease.
  
  
  METHODS
  The clinical and surgical variables influencing graft patency were assessed with log-rank test and Cox's proportional hazard analysis.
  
  
  RESULTS
  The primary patency rates of all FFB grafts at 3 and 5 years were 73+/-4 and 65+/-5%, respectively. By multivariate analysis, hypertension (Odds ratio 2.8, P=0.002) and critical ischemia (Odds ratio 0.42, P=0.01) significantly (P<.05) influenced long-term patency of FFB grafts.
  
  
  CONCLUSIONS
  The long-term patency of FFB grafts was not affected by procedural modifications. Graft patency was inferior in patients with severe lower limb ischemia but superior in patients with hypertension. Further study is required to clarify the mechanism of an unexpected beneficial effect of hypertension on FFB graft patency.
authors.affiliation: Division of Vascular Surgery, Department of Surgery, Samsung Medical Center (SMC), Sungkyunkwan University School of Medicine, Seoul, South Korea. ywkim@smc.samsung.co.kr
authors.forename: Y W
authors.initials: YW
authors.lastname: Kim
authors.forename: J-H
authors.initials: JH
authors.lastname: Lee
authors.forename: H G
authors.initials: HG
authors.lastname: Kim
authors.forename: S
authors.initials: S
authors.lastname: Huh
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001157:Arterial Occlusive Diseases / Q000601:surgery; D001807:Blood Vessel Prosthesis; D019992:Databases as Topic; D005260:Female; D005263:Femoral Artery / Q000601:surgery*; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D007083:Iliac Artery / Q000601:surgery; D007511:Ischemia / Q000150:complications; D007723:Korea / Q000453:epidemiology; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011446:Prospective Studies; D011475:Prosthesis Failure; D012189:Retrospective Studies; D014654:Vascular Patency