title: The role of sonographic endometrial patterns and endometrial thickness in the differential diagnosis of ectopic pregnancy.
abstract: OBJECTIVE
  The purpose of this study was to examine the usefulness of the endometrial trilaminar pattern and thickness in the diagnosis of ectopic pregnancy.
  
  
  METHODS
  We reviewed patient records for clinical and ultrasonographic data for patients with the suspicion of ectopic pregnancy. The trilaminar pattern and endometrial thickness were tested as predictors for the diagnosis of ectopic pregnancy.
  
  
  RESULTS
  The trilaminar pattern had a specificity of 94% and sensitivity of 38% (n = 403 women). The mean endometrial thickness was thinner in patients with ectopic, compared with normal pregnancy (9.5 +/- 5.7 mm vs 12.4 +/- 5.9 mm; P = .035). Patients with normal pregnancy or first-trimester losses had comparable thicknesses (12.4 +/- 5.9 mm vs 12.5 +/- 8.0 mm). The receiver operator curve showed that there was no thickness value useful for the diagnosis of ectopic pregnancy.
  
  
  CONCLUSIONS
  The trilaminar pattern is specific for the diagnosis of ectopic pregnancy, but it is associated with low sensitivity. The endometrial thickness tends to be thinner in patients with an ectopic pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, Wayne State University, Detroit, Mich 48201, USA. ahammoud@med.wayne.edu
authors.forename: Ahmad O
authors.initials: AO
authors.lastname: Hammoud
authors.forename: Ihab
authors.initials: I
authors.lastname: Hammoud
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Bujold
authors.forename: Bernard
authors.initials: B
authors.lastname: Gonik
authors.forename: Michael P
authors.initials: MP
authors.lastname: Diamond
authors.forename: Samuel C
authors.initials: SC
authors.lastname: Johnson
mesh_terms: D000328:Adult; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D015331:Cohort Studies; D003937:Diagnosis, Differential; D004717:Endometrium / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000097:blood / Q000000981:diagnostic imaging*; D012372:ROC Curve; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014463:Ultrasonography
chemical_list: D018997:Chorionic Gonadotropin, beta Subunit, Human