title: Metal ions as cofactors for the binding of inhibitors to methionine aminopeptidase: a critical view of the relevance of in vitro metalloenzyme assays.
authors.affiliation: FR 8.2 Pharmazeutische und Medizinische Chemie, Saarland University, 66041 Saarbrücken, Germany.
authors.forename: Rolf
authors.initials: R
authors.lastname: Schiffmann
authors.forename: Andreas
authors.initials: A
authors.lastname: Heine
authors.forename: Gerhard
authors.initials: G
authors.lastname: Klebe
authors.forename: Christian D P
authors.initials: CD
authors.lastname: Klein
mesh_terms: D000626:Aminopeptidases / Q000037:antagonists & inhibitors / Q000737:chemistry*; D001665:Binding Sites; D002413:Cations, Divalent / Q000737:chemistry; D003035:Cobalt / Q000737:chemistry; D003067:Coenzymes / Q000737:chemistry; D029968:Escherichia coli Proteins / Q000037:antagonists & inhibitors / Q000737:chemistry*; D008666:Metalloendopeptidases / Q000037:antagonists & inhibitors / Q000737:chemistry*; D063208:Methionyl Aminopeptidases; D011480:Protease Inhibitors / Q000737:chemistry*; D011728:Pyridones / Q000737:chemistry; D013827:Thiabendazole / Q000737:chemistry
chemical_list: D002413:Cations, Divalent; D003067:Coenzymes; D029968:Escherichia coli Proteins; D011480:Protease Inhibitors; D011728:Pyridones; D003035:Cobalt; D000626:Aminopeptidases; D063208:Methionyl Aminopeptidases; D008666:Metalloendopeptidases; D013827:Thiabendazole