Pulmonary hypertension in primary Sjögren's syndrome: report of a case and review of the literature.
A 61-year-old female with a history of vaginal dryness, Raynaud's phenomenon, xerostomia and xerophthalmia presented with exertional dyspnoea and weakness. Laboratory and instrumental examinations enabled us to make the diagnosis of primary Sjögren's syndrome, while cardiologic and imaging investigations evidenced isolated pulmonary hypertension and ruled out pulmonary fibrosis. Oral anticoagulant and furosemide therapy induced a partial improvement of exertional dyspnoea and weakness.
Bertoni
M
M
Divisione di Medicina Interna, Ospedale di Prato, Piazza Ospedale, Italy. micbertoni@libero.it
Niccoli
L
L
Porciello
G
G
Storri
L
L
Nannini
C
C
Manes
A
A
Palazzini
M
M
Galiè
N
N
Cantini
F
F
D000925:Anticoagulants / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D005665:Furosemide / Q000627:therapeutic use; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D008875:Middle Aged; D012129:Respiratory Function Tests; D018570:Risk Assessment; D012720:Severity of Illness Index; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018608:Ultrasonography, Doppler
D000925:Anticoagulants; D005665:Furosemide