title: How complete is full thickness disc resection of bowel endometriotic lesions? A prospective surgical and histological study.
abstract: BACKGROUND
  This study aims to evaluate the completeness of full thickness disc resection in the treatment of deep endometriotic bowel lesions.
  
  
  METHODS
  This study comprised 16 women with bowel endometriotic lesions requiring segmental resection. For the purpose of the study, before intestinal resection, nodulectomy was performed. The presence of endometriotic infiltration in direct continuity with the removed nodule and the presence of fibrosis in the area surrounding the nodule were histologically evaluated.
  
  
  RESULTS
  In seven out of 16 cases (43.8%; 95% CI, 19.8-70.1), endometriosis was found in the bowel wall adjacent to the site of nodulectomy; the infiltration was visible in the muscular layer in all cases. In cases of incomplete nodulectomy, the muscular layer of the bowel segment surrounding the endometriotic nodule contained limited or no fibrosis.
  
  
  CONCLUSIONS
  Full thickness disc resection is not complete in > or =40% of women with bowel endometriosis. Our finding that fibrosis in the muscular layer, the main landmark during surgical resection, does not always surround bowel endometriotic lesions might explain why incomplete resection may occur.
authors.affiliation: Department of Obstetrics and Gynaecology, San Martino Hospital and University of Genoa, Italy. vremorgida@yahoo.it
authors.forename: V
authors.initials: V
authors.lastname: Remorgida
authors.forename: N
authors.initials: N
authors.lastname: Ragni
authors.forename: S
authors.initials: S
authors.lastname: Ferrero
authors.forename: P
authors.initials: P
authors.lastname: Anserini
authors.forename: P
authors.initials: P
authors.lastname: Torelli
authors.forename: E
authors.initials: E
authors.lastname: Fulcheri
mesh_terms: D000328:Adult; D013505:Digestive System Surgical Procedures / Q000379:methods; D004715:Endometriosis / Q000150:complications / Q000473:pathology* / Q000601:surgery*; D005260:Female; D005355:Fibrosis; D006801:Humans; D007410:Intestinal Diseases / Q000209:etiology / Q000473:pathology* / Q000601:surgery*; D007422:Intestines / Q000473:pathology / Q000601:surgery; D010535:Laparoscopy; D007813:Laparotomy; D011446:Prospective Studies