MSight: an image analysis software for liquid chromatography-mass spectrometry.
Images obtained from high-throughput mass spectrometry (MS) contain information that remains hidden when looking at a single spectrum at a time. Image processing of liquid chromatography-MS datasets can be extremely useful for quality control, experimental monitoring and knowledge extraction. The importance of imaging in differential analysis of proteomic experiments has already been established through two-dimensional gels and can now be foreseen with MS images. We present MSight, a new software designed to construct and manipulate MS images, as well as to facilitate their analysis and comparison.
Palagi
Patricia M
PM
Proteome Informatics Group, Swiss Institute of Bioinformatics, Geneva, Switzerland. patricia.palagi@isb-sib.ch
Walther
Daniel
D
Quadroni
Manfredo
M
Catherinet
Sébastien
S
Burgess
Jennifer
J
Zimmermann-Ivol
Catherine G
CG
Sanchez
Jean-Charles
JC
Binz
Pierre-Alain
PA
Hochstrasser
Denis F
DF
Appel
Ron D
RD
D002853:Chromatography, Liquid; D015180:Electrophoresis, Gel, Two-Dimensional; D007091:Image Processing, Computer-Assisted; D010455:Peptides / Q000032:analysis; D020543:Proteome / Q000032:analysis; D012984:Software; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
D010455:Peptides; D020543:Proteome