[Molecular biology advance in the Rh blood group system].
The Rh blood group system is one of the most complex of the known human blood group polymorphisms, including above 45 blood group antigens. Considerable progress has been made in our understanding of the molecular basis of Rh in the past 10 years. The bases of Rh inheritance, RH gene and its evolution, the structure and function of Rh complex, as well as nonerythroid Rh homolog, have been determined. Further improvements have been made in the technology of Rh genotyping. The review provides an update on the advance of Rh blood group to give information in the practice of forensic science.
Sun
Zhi-gang
ZG
School of Forensic Medicine, China Medical University, Shenyang 110001, China.
Ding
Mei
M
Wang
Bao-jie
BJ
D001789:Blood Group Antigens / Q000235:genetics; D001798:Blood Proteins / Q000235:genetics / Q000276:immunology; D016172:DNA Fingerprinting; D005554:Forensic Medicine / Q000379:methods; D005838:Genotype; D006801:Humans; D008967:Molecular Biology; D009154:Mutation; D011110:Polymorphism, Genetic; D012204:Rh-Hr Blood-Group System / Q000235:genetics*
D001789:Blood Group Antigens; D001798:Blood Proteins; D012204:Rh-Hr Blood-Group System