title: The psychotic spectrum: validity and reliability of the Structured Clinical Interview for the Psychotic Spectrum.
abstract: This study evaluates the validity and the reliability of a new instrument developed to assess the psychotic spectrum: the Structured Clinical Interview for the Psychotic Spectrum (SCI-PSY). The instrument is based on a spectrum model that emphasizes soft signs, low-grade symptoms, subthreshold syndromes, as well as temperamental and personality traits comprising the clinical and subsyndromal psychotic manifestations. The items of the interview include, in addition to a subset of the DSM-IV criteria for psychotic syndromes, a number of features derived from clinical experience and from a review of the phenomenological descriptions of psychoses. Study participants were enrolled at 11 Italian Departments of Psychiatry located at 9 sites and included 77 consecutive patients with schizophrenia or schizoaffective disorder, 66 with borderline personality disorder, 59 with psychotic mood disorders, 98 with non-psychotic mood disorders and 57 with panic disorder. A comparison group of 102 unselected controls was enrolled at the same sites. The SCI-PSY significantly discriminated subjects with any psychiatric diagnosis from controls and subjects with from those without psychotic disorders. The hypothesized structure of the instrument was confirmed empirically.
authors.affiliation: Department of Psychiatry, University of Pisa, Via Roma 67, 56127 Pisa, Italy. alfredosbrana@virgilio.it
authors.forename: A
authors.initials: A
authors.lastname: Sbrana
authors.forename: L
authors.initials: L
authors.lastname: Dell'Osso
authors.forename: A
authors.initials: A
authors.lastname: Benvenuti
authors.forename: P
authors.initials: P
authors.lastname: Rucci
authors.forename: P
authors.initials: P
authors.lastname: Cassano
authors.forename: S
authors.initials: S
authors.lastname: Banti
authors.forename: C
authors.initials: C
authors.lastname: Gonnelli
authors.forename: M R
authors.initials: MR
authors.lastname: Doria
authors.forename: L
authors.initials: L
authors.lastname: Ravani
authors.forename: S
authors.initials: S
authors.lastname: Spagnolli
authors.forename: L
authors.initials: L
authors.lastname: Rossi
authors.forename: F
authors.initials: F
authors.lastname: Raimondi
authors.forename: M
authors.initials: M
authors.lastname: Catena
authors.forename: J
authors.initials: J
authors.lastname: Endicott
authors.forename: E
authors.initials: E
authors.lastname: Frank
authors.forename: D J
authors.initials: DJ
authors.lastname: Kupfer
authors.forename: G B
authors.initials: GB
authors.lastname: Cassano
mesh_terms: D000293:Adolescent; D000328:Adult; D001883:Borderline Personality Disorder / Q000175:diagnosis / Q000523:psychology; D010054:Brief Psychiatric Rating Scale; D039721:Diagnostic and Statistical Manual of Mental Disorders; D006801:Humans; D007406:Interview, Psychological; D008875:Middle Aged; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000523:psychology; D015203:Reproducibility of Results; D012559:Schizophrenia / Q000175:diagnosis; D012565:Schizophrenic Psychology; D011795:Surveys and Questionnaires