[The appraisal of the level of photo- and peroxide resistance of human erythrocytic and lymphocytic cells in presence of biogenic amines].
The changes of photo- and peroxide resistance of erythrocytic and lymphocytic cells of human under influence of UV and some active oxygen forms in presence of biogenic amines such as serotonin, dopamine, adrenalin, histamine had been investigated. While investigating the degree of photohemolysis of erythrocytes it was discovered that biogenic compounds raise UV stability of erythrocytic membranes. By using the method of chemiluminescence it was established that biogenic amines increased the degree of peroxide resistance of human erythrocytic and lymphocytic cells. The decrease of the level of erythrocytic diene conjugates under influence of UV by serotonin and histamine was also discovered.
Nakvasina
M A
MA
Popova
L I
LI
Golub
N V
NV
Artiukhov
V G
VG
D001679:Biogenic Amines / Q000494:pharmacology*; D001782:Blood Donors; D003627:Data Interpretation, Statistical; D004298:Dopamine / Q000494:pharmacology; D004837:Epinephrine / Q000494:pharmacology; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D004912:Erythrocytes / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects*; D006461:Hemolysis; D006632:Histamine / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D007202:Indicators and Reagents; D015227:Lipid Peroxidation; D008163:Luminescent Measurements; D008214:Lymphocytes / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects*; D010545:Peroxides / Q000378:metabolism; D010777:Photochemistry; D010782:Photolysis; D012701:Serotonin / Q000494:pharmacology; D013053:Spectrophotometry; D014466:Ultraviolet Rays
D001679:Biogenic Amines; D007202:Indicators and Reagents; D010545:Peroxides; D012701:Serotonin; D006632:Histamine; D004298:Dopamine; D004837:Epinephrine