Slitlamp biomicroscopy of the tear film of patients using topical Restasis and Refresh Endura.
We describe a technique in which slitlamp biomicroscopy is performed to evaluate eyes in patients using a topical dry-eye agent; ie, topical cyclosporine A ophthalmic emulsion 0.05% (Restasis) or glycerin 1%-polysorbate 80 1% (Refresh Endura). Both are delivered in an oil-emulsion formulation. We also describe a previously unreported physical finding in the tear film of these patients. The examination technique can help confirm patient compliance and the tear-film stability of the 2 agents.
Solomon
Renée
R
Ophthalmic Consultants of Long Island, Rockville Centre, New York 11570, USA.
Perry
Henry D
HD
Donnenfeld
Eric D
ED
Greenman
Herb E
HE
D000287:Administration, Topical; D016572:Cyclosporine / Q000008:administration & dosage; D003941:Diagnostic Techniques, Ophthalmological; D004359:Drug Therapy, Combination; D015352:Dry Eye Syndromes / Q000188:drug therapy*; D004655:Emulsions; D005990:Glycerol / Q000008:administration & dosage; D006801:Humans; D050356:Lipid Metabolism; D008055:Lipids / Q000737:chemistry*; D008823:Micelles; D008853:Microscopy; D009883:Ophthalmic Solutions / Q000008:administration & dosage*; D010349:Patient Compliance; D011136:Polysorbates / Q000008:administration & dosage; D013666:Tears / Q000737:chemistry* / Q000378:metabolism
D004655:Emulsions; D008055:Lipids; D008823:Micelles; D009883:Ophthalmic Solutions; D011136:Polysorbates; D016572:Cyclosporine; D005990:Glycerol