Prevalence and control of dyslipidemia among persons with diabetes in the United States.
OBJECTIVE
We assessed the prevalence, treatment, and control of dyslipidemia among United States (U.S.) adults with diabetes.


METHODS
Among 498 adults (projected to 13.4 million) aged >or=18 years with diabetes representative of the U.S. population and surveyed within the cross-sectional National Health and Nutrition Examination Survey 1999-2000, control of lipids was classified according to American Diabetes Association criteria. The extent of low density lipoprotein-cholesterol (LDL-C), high density lipoprotein-cholesterol (HDL-C), and triglyceride (TG) control was examined by gender and ethnicity, in comparison to those without diabetes, and according to lipid-lowering treatment. Analyses were weighted to the U.S. population.


RESULTS
Less than one-third of men and only one-fifth of women with diabetes are in control for LDL-C, defined as <2.6 mmol/l (<100mg/dl); over 70% are not at goal. Over half of men and over two-thirds of women have low levels of HDL-C (<or=1.0 mmol/l [<40 mg/dl] in men or <or=1.3 mmol/l [<or=50mg/dl] in women) and over half have elevated levels of triglycerides (>or=1.7 mmol/l [150 mg/dl]). Low HDL-C was more common in Caucasians (70.1%) than in Hispanics (58.8%) or African-Americans (41.5%) (p<0.001). 28.2% of subjects with diabetes were on lipid-lowering treatment. Control of LDL-C did not differ by treatment status and only 3% of subjects were controlled to target levels for all lipids.


CONCLUSIONS
Many persons with diabetes remain uncontrolled for dyslipidemia. Intensified efforts at screening and treatment according to current guidelines are warranted.
Jacobs
Milagros J
MJ
Heart Disease Prevention Program, C240 Medical Sciences, University of California, Irvine, CA 92697, USA.
Kleisli
Thomas
T
Pio
Jose R
JR
Malik
Shaista
S
L'Italien
Gilbert J
GJ
Chen
Roland S
RS
Wong
Nathan D
ND
D015992:Body Mass Index; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D048909:Diabetes Complications / Q000097:blood / Q000453:epidemiology*; D050171:Dyslipidemias / Q000097:blood / Q000453:epidemiology*; D005260:Female; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012907:Smoking / Q000009:adverse effects; D012955:Societies, Medical; D014280:Triglycerides / Q000097:blood; D014481:United States / Q000453:epidemiology
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides