Statin-mediated inhibition of Rho: only to get more NO?
Brandes
Ralf P
RP
D019883:Alkyl and Aryl Transferases / Q000378:metabolism; D000818:Animals; D004730:Endothelium, Vascular / Q000187:drug effects / Q000201:enzymology; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology*; D009569:Nitric Oxide / Q000096:biosynthesis*; D019001:Nitric Oxide Synthase / Q000378:metabolism*; D052250:Nitric Oxide Synthase Type III; D011817:Rabbits; D015398:Signal Transduction; D014661:Vasoconstriction; D020742:rhoA GTP-Binding Protein / Q000037:antagonists & inhibitors*
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; D052250:Nitric Oxide Synthase Type III; D019883:Alkyl and Aryl Transferases; C068462:rhoA p21 geranylgeranyltransferase; D020742:rhoA GTP-Binding Protein