title: Susceptibility to moxifloxacin of pneumococci isolated in English hospitals participating in the European Antimicrobial Resistance Surveillance System (EARSS) in 2003.
abstract: Susceptibility to moxifloxacin, penicillin and erythromycin was determined for 592 invasive Streptococcus pneumoniae collected from 20 English hospitals participating in the European Antimicrobial Resistance Surveillance System (EARSS) during 2003. Resistance to moxifloxacin, penicillin and erythromycin was observed in 0.8%, 5.4% and 13% of the isolates, respectively. These results show that the large majority of pneumococci were susceptible to moxifloxacin in 2003, the year when it was licensed for clinical use in the UK.
authors.affiliation: Department of Healthcare-Associated Infection and Antimicrobial Resistance, Communicable Disease Surveillance Centre, HPA Centre for Infections, Colindale, London NW9 5EQ, UK. Alan.Johnson@hpa.org.uk
authors.forename: Alan P
authors.initials: AP
authors.lastname: Johnson
authors.forename: Theresa L
authors.initials: TL
authors.lastname: Lamagni
authors.forename: Martin
authors.initials: M
authors.lastname: Wale
authors.forename: Sue
authors.initials: S
authors.lastname: Cavendish
authors.forename: Louise
authors.initials: L
authors.lastname: Bishop
authors.forename: Neelam
authors.initials: N
authors.lastname: Alhaddad
authors.forename: Marina
authors.initials: M
authors.lastname: Warner
authors.forename: David M
authors.initials: DM
authors.lastname: Livermore
authors.forename: Georgia
authors.initials: G
authors.lastname: Duckworth
authors.forename: Robert C
authors.initials: RC
authors.lastname: George
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001372:Aza Compounds / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D004739:England; D004917:Erythromycin / Q000494:pharmacology; D024841:Fluoroquinolones; D006801:Humans; D007297:Inpatients; D008826:Microbial Sensitivity Tests; D000077266:Moxifloxacin; D010406:Penicillins / Q000494:pharmacology; D011804:Quinolines / Q000494:pharmacology*; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D001372:Aza Compounds; D024841:Fluoroquinolones; D010406:Penicillins; D011804:Quinolines; D004917:Erythromycin; D000077266:Moxifloxacin