Analyses of prognostic indices of chronic liver failure caused by hepatitis virus.
OBJECTIVE
To analyze the related indices about the prognoses of chronic liver failure caused by hepatitis virus.


METHODS
Retrospectively reviewed 320 cases of chronic liver failure caused by hepatitis viruses. An improved group and an ineffective group (IG) were made to compare and analyze their clinical manifestations, laboratory examination indices and complications. Logistic regression was also carried out.


RESULTS
There were significant differences (P<0.05) between the improved group and the IG upon such indices as age, bilirubin, prothrombin time, albumin, alpha fetoprotein, the size of liver and complications (P<0.05). The regression formula was as follows: P = 1/(1+e(-y)) (y = 1.7262-0.0948X(1)+2.9846X(2)+0.6992X(3)+1.6019X(4)+ 2.0398X(5)). (Note: X(1)-Prothrombin activity; X(2)-digestive tract hemorrhage; X(3)-hepatic encephalopathy; X(4)-hepatorenal syndrome; X(5)-pulmonary infection.).


CONCLUSIONS
Laboratory examination such as bilirubin, prothrombin time and alpha fetoprotein can be regarded as indices of the prognoses of chronic liver failure caused by hepatitis. Moreover, the regression equation can evaluate prognoses more comprehensively and direct our treatments.
Li
Xiao-Mao
XM
Department of Obstetrics and Gynecology, Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China. tigerlee777@163.net
Ma
Lin
L
Yang
Yue-Bo
YB
Shi
Zhong-Jie
ZJ
Zhou
Shui-Sheng
SS
D000328:Adult; D001663:Bilirubin / Q000097:blood; D002908:Chronic Disease; D006525:Hepatitis, Viral, Human / Q000150:complications*; D006801:Humans; D017093:Liver Failure / Q000097:blood / Q000503:physiopathology* / Q000821:virology*; D008875:Middle Aged; D011379:Prognosis; D011517:Prothrombin Time; D012189:Retrospective Studies; D000509:alpha-Fetoproteins / Q000032:analysis
D000509:alpha-Fetoproteins; D001663:Bilirubin