title: Metabolism of daidzein by Nocardia species NRRL 5646 and Mortierella isabellina ATCC 38063.
abstract: The phytoestrogen daidzein was metabolized by Nocardia species NRRL 5646 to give two metabolites obtained by hydroxylation and methylation. These metabolites were spectrally characterized as 7-methoxy-4'-hydroxyisoflavone (isoformononetin) and 7,8-dimethoxy-4'-hydroxyisoflavone. Mortierella isabellina ATCC 38063 was able to metabolize daidzein to the unusual metabolite daidzein-4'-rhamnopyranoside.
authors.affiliation: Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt. galaltm@yahoo.com
authors.forename: Galal T
authors.initials: GT
authors.lastname: Maatooq
authors.forename: John P N
authors.initials: JP
authors.lastname: Rosazza
mesh_terms: D006900:Hydroxylation; D007529:Isoflavones / Q000378:metabolism*; D008745:Methylation; D008956:Models, Chemical; D015394:Molecular Structure; D020094:Mortierella / Q000378:metabolism*; D009615:Nocardia / Q000378:metabolism*; D048789:Phytoestrogens / Q000378:metabolism*
chemical_list: D007529:Isoflavones; D048789:Phytoestrogens; C004742:daidzein