title: HSP27 and cell death in spinocerebellar ataxia type 3.
abstract: Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant spinocerebellar degeneration characterized by a wide range of clinical manifestations. In this review, we discuss the role(s) that heat shock protein 27 (HSP27) may play in the cell death process of spinocerebellar ataxia type 3.
authors.affiliation: Department of Life Science, Tunghai University, Taichung, Taiwan, Republic of China. mhsieh@mail.thu.edu.tw
authors.forename: Mingli
authors.initials: M
authors.lastname: Hsieh
authors.forename: Hui-Fang
authors.initials: HF
authors.lastname: Tsai
authors.forename: Wei-Hsiu
authors.initials: WH
authors.lastname: Chang
mesh_terms: D000818:Animals; D016923:Cell Death / Q000502:physiology; D055551:HSP27 Heat-Shock Proteins; D006360:Heat-Shock Proteins / Q000378:metabolism*; D006801:Humans; D017827:Machado-Joseph Disease / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D008954:Models, Biological; D018832:Molecular Chaperones; D009363:Neoplasm Proteins / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology
chemical_list: D055551:HSP27 Heat-Shock Proteins; C057725:HSPB1 protein, human; D006360:Heat-Shock Proteins; D018832:Molecular Chaperones; D009363:Neoplasm Proteins