title: [Role of trypan blue in epiretinal membrane surgery].
abstract: BACKGROUND
  Idiopathic epiretinal membrane (ERM) results from detachment of the posterior hyaloid. Vitrectomy and peeling are the treatment of choice. Trypan blue 0.15% (TB) stains the epiretinal membrane and the internal limiting membrane (ILM), facilitating surgery and thus allowing selective and complete removal with less retinal damage. We conducted a study evaluating the advantages of selective staining associated with surgery, the incidence of postoperative damage, and the influence on final visual acuity.
  
  
  METHODS
  Fourteen patients were operated on by the same surgeon, who carried out a complete vitrectomy, then fluid-air exchange for dye injection of undiluted 0.2 ml of Trypan blue 0.15% in front of the membrane, which was then easily distinguished from the area under the retina. Preoperative visual acuity, postoperative damage, as well as eye status at the end of follow-up are discussed. Transmission electron microscopy was used to determine if epiretinal membrane removal was complete and selective. Angiography was systematically used to study the state of retina before and after surgery.
  
  
  RESULTS
  Preliminary results show that trypan blue is useful and facilitates complete removal of ERM and ILM. It may reduce long-term complications and recurrent membrane formation. Trypan blue is a staining agent that is quick and easy to use. It presents no short-term toxic effects. Functional results in 6 months show improvement of visual acuity and disappearance of metamorphopsia.
  
  
  CONCLUSIONS
  Idiopathic epiretinal membrane surgery with tryptan blue staining is a better alternative than indocyanine green staining.
authors.affiliation: Service d'Ophtalmologie, CHU de Poitiers, France.
authors.forename: S
authors.initials: S
authors.lastname: Balayre
authors.forename: M
authors.initials: M
authors.lastname: Boissonnot
authors.forename: L
authors.initials: L
authors.lastname: Curutchet
authors.forename: P
authors.initials: P
authors.lastname: Dighiero
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004396:Coloring Agents; D019773:Epiretinal Membrane / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D046529:Microscopy, Electron, Transmission; D008875:Middle Aged; D011183:Postoperative Complications; D012008:Recurrence; D013997:Time Factors; D014343:Trypan Blue; D014786:Vision Disorders; D014792:Visual Acuity; D014821:Vitrectomy
chemical_list: D004396:Coloring Agents; D014343:Trypan Blue