Studies on antipyretic and anti-inflammatory activities of Scaevola frutescens.
The aim of the present study was to investigate the anti-inflammatory and antipyretic effects of a methanolic extract of Scaevola frutescens leaves by carrageenan-induced paw edema and yeast-induced pyrexia in rats. The plant extract showed a significant reduction in yeast-induced hyperthermia and carrageenan induced paw edema and the effects were comparable to the standard drugs, paracetamol and indomethacin respectively.
Umadevi
S
S
Department of Pharmacy, Faculty of Engineering and Technology, Annamalai University, Tamil Nadu, India. umadevi_viji@rediffmail.com
Mohanta
G P
GP
Manavalan
R
R
D018712:Analgesics, Non-Narcotic / Q000138:chemical synthesis* / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis* / Q000494:pharmacology*; D002351:Carrageenan; D004487:Edema / Q000139:chemically induced / Q000517:prevention & control; D005334:Fever / Q000139:chemically induced / Q000517:prevention & control; D051379:Mice; D018515:Plant Leaves / Q000737:chemistry; D010944:Plants / Q000737:chemistry* / Q000633:toxicity; D051381:Rats
D018712:Analgesics, Non-Narcotic; D000894:Anti-Inflammatory Agents, Non-Steroidal; D002351:Carrageenan