[(CAG) n polymorphism of androgen receptor gene in idiopathic azoospermic and oligospermic Chinese men].
OBJECTIVE
To research (CAG)n polymorphism of androgen receptor gene in idiopathic azoospermic and oligospermic Chinese men, and to explore its correlation with the development of dyszoospermia.


METHODS
Fifty-two men with oligospermia and 31 with azoospermia were enrolled, the number of CAG sequence repeats determined by PCR and denaturing polyacrylamide gel electrophoresis (PAGE), and (CAG)n polymorphism analyzed.


RESULTS
The CAG repeats in the men with oligospermia and those with azoospermia were 22.19 and 22.13 respectively.


CONCLUSIONS
The polymorphism of the repeat length of the (CAG) n satellite in androgen receptor gene may affect spermatogenesis and have a less important role in male infertility.
Li
Zuo-Xiang
ZX
Peking Union Medical College, Beijing 100730, China.
Tang
Wen-Hao
WH
Wang
Zhao-Hui
ZH
Wang
Lin
L
Wang
Yuan-Yuan
YY
Ma
Lu-Lin
LL
Ma
Xu
X
D000328:Adult; D004591:Electrophoresis, Polyacrylamide Gel; D005091:Exons; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D008297:Male; D009845:Oligospermia / Q000235:genetics; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011944:Receptors, Androgen / Q000235:genetics*; D018911:Trinucleotide Repeats / Q000235:genetics*
D011944:Receptors, Androgen