The transcription termination factor Rho is essential and autoregulated in Caulobacter crescentus.
The impossibility of obtaining a rho null mutant and sensitivity to bicyclomycin have indicated that rho is essential for the viability of Caulobacter crescentus. Transcription gene fusions of sequences with serial deletions of the rho 5' untranslated region (5'-UTR) with a lacZ reporter gene indicated that rho is autoregulated at the level of attenuation of transcription in the 5'-UTR.
Italiani
Valéria C S
VC
Department of Microbiology, Institute of Biomedical Sciences, Universidade de São Paulo, SP, Brazil.
Marques
Marilis V
MV
D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D001483:Base Sequence; D016935:Caulobacter crescentus / Q000235:genetics / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial / Q000502:physiology*; D008969:Molecular Sequence Data; D009154:Mutation; D012234:Rho Factor / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D014158:Transcription, Genetic
D001426:Bacterial Proteins; D012234:Rho Factor