Familial bilateral acinic cell carcinoma of the parotid synchronous with pituitary adenoma: case report.
BACKGROUND
Acinic cell carcinoma is a common neoplasm of the salivary glands that occurs predominately in the parotid. Only one case of a familial recurrence of such a neoplasm and 16 cases of bilateral tumors have been reported.


METHODS
History files and histologic reports of a patient with bilateral multifocal acinic cell carcinoma of the parotid and a synchronous pituitary adenoma, and of the patient's sister and his father, also treated for parotid tumours, were retrieved.


RESULTS
There was one recurrence of acinic cell carcinoma in the family. A pituitary tumor was a chromophobe gonotrophic adenoma.


CONCLUSIONS
This is the 17th case of bilateral acinic cell carcinoma of the parotid gland and the second reported case with a familial recurrence. It is the first with a synchronous pituitary adenoma.
Delides
Alexander
A
Department of Otolaryngology, Athens Medical Center, Distomou 5-7, Marousi, 151 25 Athens, Greece. aldelan3@otenet.gr
Velegrakis
George
G
Kontogeorgos
George
G
Karagianni
Evangelia
E
Nakas
Dimitris
D
Helidonis
Emmanuel
E
D000236:Adenoma / Q000175:diagnosis*; D018267:Carcinoma, Acinar Cell / Q000175:diagnosis* / Q000235:genetics; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D010307:Parotid Neoplasms / Q000175:diagnosis* / Q000235:genetics; D010911:Pituitary Neoplasms / Q000175:diagnosis*