title: Somatic symptoms in late-life anxiety: treatment issues.
abstract: Understanding and addressing somatic symptoms are complex in older adults, who have more comorbid medical illnesses. This article describes a systematic review of the literature on somatic symptoms in older patients with anxiety disorders. Additionally, the hypothesis was tested that somatic symptoms would respond to selective serotonin reuptake inhibitor treatment in 30 anxious patients aged 60 years and older who participated in a 32-week trial of citalopram. The literature review showed few original data articles about somatic symptoms in older patients with anxiety disorders. These articles suggest that such a relationship is common and that treatment of anxiety, or anxious depression, is associated with a reduction in somatic symptoms. In the analysis, citalopram treatment was associated with a significant decrease in several somatic symptoms from pretreatment baseline. It is concluded that somatic symptoms in older adults with anxiety disorders or anxious depression often improve with successful antidepressant treatment. However, additional treatment and integrated approaches are likely to be necessary for many such individuals.
authors.affiliation: Intervention Research Center for Late-Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA. lenzeej@upmc.edu
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Lenze
authors.forename: Jordan F
authors.initials: JF
authors.lastname: Karp
authors.forename: Benoit H
authors.initials: BH
authors.lastname: Mulsant
authors.forename: Stephen
authors.initials: S
authors.lastname: Blank
authors.forename: M Katherine
authors.initials: MK
authors.lastname: Shear
authors.forename: Patricia R
authors.initials: PR
authors.lastname: Houck
authors.forename: Charles F
authors.initials: CF
authors.lastname: Reynolds
mesh_terms: D017668:Age of Onset; D000368:Aged; D001008:Anxiety Disorders / Q000150:complications / Q000523:psychology* / Q000628:therapy*; D015283:Citalopram / Q000627:therapeutic use*; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy / Q000209:etiology / Q000523:psychology; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D013001:Somatoform Disorders / Q000188:drug therapy* / Q000209:etiology*; D016896:Treatment Outcome
chemical_list: D015283:Citalopram; D017367:Selective Serotonin Reuptake Inhibitors