title: Temporal changes in bacterial resistance in German intensive care units, 2001-2003: data from the SARI (surveillance of antimicrobial use and antimicrobial resistance in intensive care units) project.
abstract: Conservative testing revealed a stable antibiotic resistance situation for Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Enterobacter cloacae in 32 German intensive care units (ICUs) actively participating in the SARI (surveillance of antimicrobial use and antimicrobial resistance in ICUs) project over a three-year period (2001--2003). No significant changes were shown for methicillin-resistant S. aureus (MRSA) (P=0.501; the MRSA rate increased in 18 ICUs and decreased in 14 ICUs). The only exception was an increase in ciprofloxacin-resistant E. coli.
authors.affiliation: Institute of Environmental Medicine and Hospital Epidemiology, University Hospital Freiburg, Hugstetter Str 55, 79106 Freiburg, Germany. elisabeth.meyer@uniklinik-freiburg.de
authors.forename: E
authors.initials: E
authors.lastname: Meyer
authors.forename: F
authors.initials: F
authors.lastname: Schwab
authors.forename: D
authors.initials: D
authors.lastname: Jonas
authors.forename: H
authors.initials: H
authors.lastname: Ruden
authors.forename: P
authors.initials: P
authors.lastname: Gastmeier
authors.forename: F D
authors.initials: FD
authors.lastname: Daschner
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D001424:Bacterial Infections / Q000188:drug therapy / Q000382:microbiology*; D002939:Ciprofloxacin / Q000494:pharmacology; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D016972:Enterobacter cloacae / Q000187:drug effects* / Q000302:isolation & purification; D004926:Escherichia coli / Q000187:drug effects* / Q000302:isolation & purification; D005858:Germany; D006801:Humans; D007362:Intensive Care Units / Q000706:statistics & numerical data*; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000302:isolation & purification; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000302:isolation & purification; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin