title: [Sinupret in treatment of acute inflammation of the middle ear in children].
abstract: The acute inflammation of middle ear (AIE) represents one of the most common diseases in pediatric practice. In the uncomplicated cases of AIE the pathogenesis of the diseases depends mainly on the disturbance of the evacuation drainage of the Eustachian tube. In such cases peroral administration of the preparations "Sinupret" produced by "BIONORIKA AG GERMANY" causes a mucolytic effect in the tube. In Tbilisi M. Guramishvili pediatric clinic 40 patients with AIE have been observed. In 20 cases only Sinupret has been used. In the control group (20 cases) antibiotics were employed together with ear and nose drops. Results of the observation showed that: Sinupret is effective for treatment of I-II stages of AIE; sinupret is indicated as monotherapy for the uncomplicated cases of AIE; therapy with antibiotics gives moderate effect in AIE treatment but may cause recurrences. The choice of therapy should depend on the evaluation of otoscopic and timpanometric data.
authors.affiliation: M. Guramishvili Pediatric Clinic, Tbilisi, Georgia.
authors.forename: K
authors.initials: K
authors.lastname: Gotsadze
mesh_terms: D000158:Acoustic Impedance Tests; D000208:Acute Disease; D000284:Administration, Oral; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010033:Otitis Media / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D038781:Otoscopy; D010936:Plant Extracts / Q000008:administration & dosage / Q000627:therapeutic use*; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014432:Tympanic Membrane / Q000473:pathology
chemical_list: D010936:Plant Extracts; C028353:Sinupret