title: [Study on mortality by specific cause among workers at a lead and zinc foundry in Sardinia].
abstract: The mortality of 918 Sardinian lead-smelter workers followed between 1972 and 2001 is reported. The assessment of individual exposure to inorganic lead was based on several environmental and blood lead measurements available, for each department and task, between 1985 and 2001. The mortality for all cancers was within the expected numbers (SMR 1.01, n 108). Even if not statistically significant, the mortality for gastric cancer (SMR 1.22, n 4), for lung cancer (SMR 1.21, n 18) and for lymphomas and leukaemias (SMR 1.82, n 6) was higher than that expected from the regional rates during the follow-up. Only for the lung cancer mortality a statistically significant upward trend with increasing categories of lead exposure was observed (SMR 1.96, 95% CI 1.02-3.68 for the highest exposure group). Our study, even if of small size, suggests an association between occupational exposure to inorganic lead and lung cancer risk.
authors.affiliation: Dipartimento di Sanita Pubblica-Sezione di Medicina del Lavoro, Università degli Studi di Cagliari, Italy. cartapl@pacs.unica.it
authors.forename: P
authors.initials: P
authors.lastname: Carta
authors.forename: G
authors.initials: G
authors.lastname: Aru
authors.forename: P
authors.initials: P
authors.lastname: Nurchis
authors.forename: C
authors.initials: C
authors.lastname: Cadeddu
authors.forename: M
authors.initials: M
authors.lastname: Polizzi
authors.forename: V
authors.initials: V
authors.lastname: Nieddu
authors.forename: G
authors.initials: G
authors.lastname: Sali
authors.forename: L
authors.initials: L
authors.lastname: Gaviano
authors.forename: C
authors.initials: C
authors.lastname: Flore
authors.forename: F
authors.initials: F
authors.lastname: Sanna Randaccio
mesh_terms: D002423:Cause of Death; D006801:Humans; D007854:Lead / Q000009:adverse effects*; D008669:Metallurgy; D009784:Occupational Diseases / Q000139:chemically induced* / Q000401:mortality*; D015032:Zinc / Q000009:adverse effects*
chemical_list: D007854:Lead; D015032:Zinc