[The relationship between acute rejection and expression of sCD30 for the patients after kidney transplantation].
OBJECTIVE
To study the relationship between the sCD30 and acute rejection.


METHODS
We tested the sCD30 level in serum for 58 cases with kidney transplantation before and the 7th day and 28th day after operation by ELISA. 31 healthy individual for control group, and simultaneously recorded the incidence of rejection after kidney transplantation.


RESULTS
The results showed that there is an obviously relation before kidney transplantation between the sCD30 level in serum and the incidence of acute rejection (chi = 4.843, P = 0.028, P < 0.05). There is a significantly relation at the 7th day after kidney transplantation between the sCD30 level in serum and the incidence of acute rejection (chi = 7.201, P = 0.007, P < 0.01). There is no obviously relation at 28th day after kidney transplantation between the sCD30 level in serum and the incidence of acute rejection (chi = 2.095, P = 0.148, P > 0.05).


CONCLUSIONS
The results suggested that the expressions of sCD30 are related to acute rejection. We speculated that the expressions of sCD30 could play an important role in acute rejection.
Yang
Jian-Lin
JL
Department of Urology, Peking University First Hospital, Institute of Urology, Peking University, Beijing 100034, China.
Hao
Hong-Jun
HJ
Qin
Bin
B
Bang
Ling-Qing
LQ
Zhang
Zhi-Hong
ZH
Xin
Dian-Qi
DQ
Guo
Ying-Lu
YL
Na
Yan-Qun
YQ
D000208:Acute Disease; D015415:Biomarkers / Q000097:blood; D002681:China / Q000453:epidemiology; D005260:Female; D006084:Graft Rejection / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control; D006085:Graft Survival / Q000276:immunology* / Q000502:physiology; D006801:Humans; D015994:Incidence; D017730:Ki-1 Antigen / Q000097:blood*; D016030:Kidney Transplantation / Q000276:immunology*; D008297:Male
D015415:Biomarkers; D017730:Ki-1 Antigen