title: Teaching resources. Proteases and signaling.
abstract: This teaching resource provides lecture notes and slides for a class covering proteases and signaling and is part of the course "Cell signaling systems: a course for graduate students." The lecture begins with a discussion of protease-activated receptors and the ubiquitin-proteasome system and then proceeds to describe some of the ways that proteolysis can function in signal transduction.
authors.affiliation: Department of Pharmacology and Biological Chemistry, Mount Sinai School of Medicine, New York, NY 10029, USA. sherwin.wilk@mssm.edu
authors.forename: Sherwin
authors.initials: S
authors.lastname: Wilk
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000502:physiology; D001296:Audiovisual Aids; D001426:Bacterial Proteins / Q000502:physiology; D001427:Bacterial Toxins; D001695:Biology / Q000193:education*; D004500:Education, Graduate; D006801:Humans; D020672:I-kappa B Proteins / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D000072000:NF-KappaB Inhibitor alpha; D016328:NF-kappa B / Q000378:metabolism; D010447:Peptide Hydrolases / Q000502:physiology*; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology*; D025801:Ubiquitin / Q000378:metabolism
chemical_list: D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D001427:Bacterial Toxins; D020672:I-kappa B Proteins; D008565:Membrane Proteins; D016328:NF-kappa B; C000606204:NFKBIA protein, human; D025801:Ubiquitin; C109227:YopP protein, Yersinia; C030325:anthrax toxin; D000072000:NF-KappaB Inhibitor alpha; D010447:Peptide Hydrolases; D046988:Proteasome Endopeptidase Complex