Isolation and structural elucidation of a novel rotenoid from the seeds of Clitoria fairchildiana.
The seeds of Clitoria fairchildiana provided a new rotenoid, 6-hydroxy-2,3,9-trimethoxy-[1]benzopyrano[3,4-b][1]benzopyran-12(6H)-one. The structural elucidation was performed using detailed analyses of H- and 13C-NMR spectra including 2DNMR spectroscopic techniques (1H-13CHETCOR) and by comparison with spectrometric data from the literature. The anti-inflammatory activity was investigated using a capillary permeability assay.
Mathias
Leda
L
Laboratório de Química de Plantas Medicinais, Núcleo de Pesquisas de Produtos Naturais, Universidade Federal do Rio de Janeiro, PO Box 68045 CEP 21944-970 Rio de Janeiro, Brazil.
Da Silva
Bernadete Pereira
BP
Mors
Walter Baptist
WB
Parente
José Paz
JP
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D031292:Clitoria / Q000737:chemistry*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008956:Models, Chemical; D015394:Molecular Structure; D012402:Rotenone / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D012639:Seeds / Q000737:chemistry*
C503378:6-hydroxy-2,3,9-trimethoxy-(1)benzopyrano(3,4-b)(1)benzopyran-12(6H)-one; D000893:Anti-Inflammatory Agents; D012402:Rotenone