title: Histidine residue at position 234 of oxidosqualene-lanosterol cyclase from saccharomyces cerevisiae simultaneously influences cyclization, rearrangement, and deprotonation reactions.
authors.affiliation: Department of Biological Science and Technology, Center for Interdisciplinary Molecular Science, National Chiao Tung University, 300 Hsin-Chu, Taiwan, Republic of China. tkwmll@mail.nctu.edu.tw
authors.forename: Tung-Kung
authors.initials: TK
authors.lastname: Wu
authors.forename: Yuan-Ting
authors.initials: YT
authors.lastname: Liu
authors.forename: Cheng-Hsian
authors.initials: CH
authors.lastname: Chang
mesh_terms: D000595:Amino Acid Sequence; D003500:Cyclization; D006639:Histidine / Q000737:chemistry* / Q000378:metabolism*; D019751:Intramolecular Transferases / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D008958:Models, Molecular; D016297:Mutagenesis, Site-Directed; D016133:Polymerase Chain Reaction; D012441:Saccharomyces cerevisiae / Q000201:enzymology*; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D014315:Triterpenes / Q000737:chemistry
chemical_list: D029701:Saccharomyces cerevisiae Proteins; D014315:Triterpenes; D006639:Histidine; D019751:Intramolecular Transferases; C021924:lanosterol synthase