title: Multifocal epithelioid hemangioendothelioma in a 16-year-old boy.
abstract: We report on a 16-year-old white male presenting with a 4-month history of syncopal episodes and occasional headaches. The CT and MRI studies revealed numerous lytic lesions of the skull base and cervical spine; subsequently, similar lesions were demonstrated in all areas of the skeleton, and CT showed numerous lesions in the lungs, liver, and kidneys. Excisional biopsy from several sites confirmed the diagnosis of epithelioid hemangioendothelioma. We conclude that epithelioid hemangioendothelioma should be added to the differential diagnosis for lytic lesions of bone that are clustered in the same anatomic region and that might also present with visceral involvement.
authors.affiliation: Department of Radiology, Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA. badler@chi.osu.edu
authors.forename: Brent
authors.initials: B
authors.lastname: Adler
authors.forename: John
authors.initials: J
authors.lastname: Naheedy
authors.forename: Nicholas
authors.initials: N
authors.lastname: Yeager
authors.forename: Kathleen
authors.initials: K
authors.lastname: Nicol
authors.forename: Jan
authors.initials: J
authors.lastname: Klamar
mesh_terms: D000293:Adolescent; D001859:Bone Neoplasms / Q000175:diagnosis; D002574:Cervical Vertebrae / Q000473:pathology; D006261:Headache / Q000209:etiology; D018323:Hemangioendothelioma, Epithelioid / Q000175:diagnosis*; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis; D008113:Liver Neoplasms / Q000175:diagnosis; D008175:Lung Neoplasms / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D019292:Skull Base Neoplasms / Q000175:diagnosis; D013125:Spinal Neoplasms / Q000175:diagnosis; D013575:Syncope / Q000209:etiology; D014057:Tomography, X-Ray Computed