[Generalized granuloma annulare: remission during treatment of HIV infection].
BACKGROUND
Granuloma annulare is a benign dermatosis characterized by pale or erythematous papules grouped in rings or in arch form figures. We report the observation combining a granuloma annulare and a Human Immunodeficiency Virus (HIV) infection, with regression of the granuloma annulare on initiation of treatment of the HIV infection.


METHODS
A 33 year-old man presented with an eruption of multiple, erythematous papules predominating on the trunk and limbs but sparing the face. Histology confirmed the diagnosis of generalized granuloma annulare. We diagnosed an HIV infection. Remission of the granuloma annulare was obtained concomitantly when immune restoration was obtained following the prescription of an antiretroviral tritherapy.


CONCLUSIONS
Since 1985, several cases of atypical forms of granuloma annulare have been reported in HIV-infected patients. Nevertheless, the precise relationship between the two diseases is unknown. The case we report on raises the question of the relationship between granuloma annulare and immunodepression.
Jacobi
D
D
Service de Dermatologie, Centre Hospitalier Universitaire Trousseau, Tours.
Rivollier
C
C
Buisson
H
H
de Muret
A
A
Besnier
J-M
JM
Lorette
G
G
D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D006099:Granuloma / Q000188:drug therapy* / Q000473:pathology; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D008297:Male; D016896:Treatment Outcome
D044966:Anti-Retroviral Agents