Production of catechol-siderophore and utilization of transferrin-bound iron in Bacillus cereus.
In the present study we attempted to ascertain whether Bacillus cereus was able to produce catechol-siderophore(s), and whether it was able to utilize transferrin-bound iron. The growth of B. cereus was stimulated in proportion to the iron-saturation level of the transferrin, and catechol-siderophores were produced in inverse proportion to this level. B. cereus was proved to uptake iron from partially iron-saturated transferrin or holotransferrin, without destroying the transferrin by its proteases. The catechol-siderophores from B. cereus were able to sustain and augment its growth on the transferrin-bound iron. These results indicate that B. cereus has the ability to produce catechol-siderophores, and to utilize transferrin-bound iron as an iron source for growth, via the siderophore-mediated iron-uptake system.
Park
Ra-Young
RY
Research Center for Resistant Cells, Department of Microbiology, Chosun University Medical School, Gwangju, ROK.
Choi
Mee-Hwa
MH
Sun
Hui-Yu
HY
Shin
Sung-Heui
SH
D001409:Bacillus cereus / Q000378:metabolism*; D002396:Catechols / Q000032:analysis / Q000378:metabolism*; D007501:Iron / Q000378:metabolism*; D017262:Siderophores / Q000032:analysis / Q000096:biosynthesis*; D014168:Transferrin / Q000378:metabolism*
D002396:Catechols; D017262:Siderophores; D014168:Transferrin; D007501:Iron; C034221:catechol