title: Breast dosimetry using high-resolution voxel phantoms.
abstract: A computer model of X-ray mammography has been developed, which uses quasi-realistic high-resolution voxel phantoms to simulate the breast. The phantoms have 400 microm voxels and simulate the three-dimensional distributions of adipose and fibro-glandular tissues, Cooper's ligaments, ducts and skin and allow the estimation of dose to individual tissues. Calculations of the incident air kerma to mean glandular dose conversion factor, g, were made using a Mo/Mo spectrum at 28 kV for eight phantoms in the thickness range 40-80 mm and of varying glandularity. The values differed from standard tabulations used for breast dosimetry by up to 43%, because of the different spatial distribution of glandular tissue within the breast. To study this further, additional voxel phantoms were constructed, which gave variations of between 9 and 59% compared with standard values. For accurate breast dosimetry, it is therefore very important to take the distribution of glandular tissues into account.
authors.affiliation: Department of Physics, The Royal Marsden NHS Foundation Trust, Fulham Road, London SW3 6JJ, UK. david.dance@rmh.nthames.nhs.uk
authors.forename: D R
authors.initials: DR
authors.lastname: Dance
authors.forename: R A
authors.initials: RA
authors.lastname: Hunt
authors.forename: P R
authors.initials: PR
authors.lastname: Bakic
authors.forename: A D A
authors.initials: AD
authors.lastname: Maidment
authors.forename: M
authors.initials: M
authors.lastname: Sandborg
authors.forename: G
authors.initials: G
authors.lastname: Ullman
authors.forename: G
authors.initials: G
authors.lastname: Alm Carlsson
mesh_terms: D001940:Breast / Q000473:pathology; D005260:Female; D006801:Humans; D008327:Mammography / Q000379:methods*; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement / Q000379:methods; D011874:Radiometry / Q000379:methods*; D014965:X-Rays