Increased glycocalicin index and normal thrombopoietin levels in patients with idiopathic thrombocytopenic purpura with a decreased rate of platelet production.
Platelet kinetic studies in idiopathic thrombocytopenic purpura (ITP) have shown that in a subgroup of patients a shortened mean platelet life (MPL) is associated with a decreased platelet production rate (PPR). Other methods of studying certain aspects of thrombocytopoiesis are the plasma concentrations of thrombopoietin and glycocalicin.
Houwerzijl
Ewout J
EJ
Louwes
Henk
H
Esselink
Mariet T
MT
Smit
Jan W
JW
Vellenga
Edo
E
de Wolf
Joost Th M
JT
D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000473:pathology; D001853:Bone Marrow / Q000473:pathology; D002470:Cell Survival; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019038:Platelet Glycoprotein GPIb-IX Complex / Q000032:analysis*; D011696:Purpura, Thrombocytopenic / Q000097:blood*; D034061:Thrombopoiesis; D013926:Thrombopoietin / Q000097:blood*
D019038:Platelet Glycoprotein GPIb-IX Complex; C023592:glycocalicin; D013926:Thrombopoietin