title: Synthesis and characterization of the monomer ruthenium complex of hypocrellin B.
abstract: We first synthesized and characterized a monomer ruthenium complex of hypocrellin B (HB) by chelation with Ru(bpy)2Cl2 (in which bpy=2,2'-bipyridine). It possesses the photosensitizing properties and can be applied in photodynamic therapy (PDT). The chemiluminescence assays indicated that the photodamage ability of the complex is stronger than that of HB.
authors.affiliation: Analysis and Testing Center, Nanjing Normal University, Nanjing 210097, China. zhoujiahong72@hotmail.com
authors.forename: Jiahong
authors.initials: J
authors.lastname: Zhou
authors.forename: Jihua
authors.initials: J
authors.lastname: Liu
authors.forename: Yuying
authors.initials: Y
authors.lastname: Feng
authors.forename: Shaohua
authors.initials: S
authors.lastname: Wei
authors.forename: Xiaotian
authors.initials: X
authors.lastname: Gu
authors.forename: Xuesong
authors.initials: X
authors.lastname: Wang
authors.forename: Baowen
authors.initials: B
authors.lastname: Zhang
mesh_terms: D000818:Animals; D002417:Cattle; D004247:DNA / Q000378:metabolism*; D015394:Molecular Structure; D010569:Perylene / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D017319:Photosensitizing Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D011809:Quinones / Q000138:chemical synthesis* / Q000494:pharmacology*; D017975:Ruthenium Compounds / Q000138:chemical synthesis* / Q000494:pharmacology*
chemical_list: D017319:Photosensitizing Agents; D011809:Quinones; D017975:Ruthenium Compounds; D010569:Perylene; D004247:DNA; C064522:hypocrellin B