title: COREX/BEST server: a web browser-based program that calculates regional stability variations within protein structures.
abstract: CONCLUSIONS
  Utilizing the user-supplied coordinates of a protein structure, the COREX/BEST Server generates a structural thermodynamic ensemble. This conformational ensemble can then be used to calculate the regional variations in stability of a protein structure, and the stabilities are presented in units of energy (kcal/mol). The regional stabilities, which are calculated at the resolution of individual residues, can be mapped onto the protein structure for visual representation and downloaded from the site in the form of tab delimited text. The site provides an easy to follow summary of the theoretical and algorithmic approaches and provides links to references for more detailed descriptions.
  
  
  BACKGROUND
  The COREX/BEST Server may be accessed through a typical web browser by visiting http://best.utmb.edu/BEST/.
authors.affiliation: Department of Human Biological Chemistry & Genetics, Sealy Center for Structural Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
authors.forename: Jason
authors.initials: J
authors.lastname: Vertrees
authors.forename: Phillip
authors.initials: P
authors.lastname: Barritt
authors.forename: Steve
authors.initials: S
authors.lastname: Whitten
authors.forename: Vincent J
authors.initials: VJ
authors.lastname: Hilser
mesh_terms: D000465:Algorithms; D001665:Binding Sites; D003196:Computer Graphics; D003198:Computer Simulation; D020407:Internet; D008956:Models, Chemical; D008958:Models, Molecular; D011485:Protein Binding; D011487:Protein Conformation; D011506:Proteins / Q000032:analysis / Q000737:chemistry*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software; D014584:User-Computer Interface
chemical_list: D011506:Proteins