title: Acceptability of five nonoxynol-9 spermicides.
abstract: OBJECTIVE
  To examine the acceptability of five nonoxynol-9 (N-9) spermicides.
  
  
  METHODS
  We analyzed data from a randomized trial of five products, including three gels containing different amounts of N-9 per dose, a film and a suppository. In the trial, 1536 participants were asked to use the assigned spermicide for 7 months and to complete questionnaires 4 weeks after admission and at discontinuation.
  
  
  RESULTS
  Overall, 43% of participants liked their spermicide "very much." This proportion was higher in the three gel groups than in the suppository and film groups. Difficulty with insertion, messiness and discontent with timing of insertion were common complaints in all groups. After adjustment for selected baseline factors, acceptability on the first questionnaire was not related to duration or consistency of subsequent spermicide use or to subsequent time to pregnancy.
  
  
  CONCLUSIONS
  In this study, all five spermicides were considered acceptable by most users. Acceptability did not appear to influence spermicide use or pregnancy risk.
authors.affiliation: Family Health International, PO Box 13950, Research Triangle Park, NC 27709, USA. eraymond@fhi.org
authors.forename: Elizabeth G
authors.initials: EG
authors.lastname: Raymond
authors.forename: Pai Lien
authors.initials: PL
authors.lastname: Chen
authors.forename: Sean
authors.initials: S
authors.lastname: Condon
authors.forename: Joanne
authors.initials: J
authors.lastname: Luoto
authors.forename: Kurt T
authors.initials: KT
authors.lastname: Barnhart
authors.forename: Mitchell D
authors.initials: MD
authors.lastname: Creinin
authors.forename: Alfred
authors.initials: A
authors.lastname: Poindexter
authors.forename: Livia
authors.initials: L
authors.lastname: Wan
authors.forename: Mark
authors.initials: M
authors.lastname: Martens
authors.forename: Robert
authors.initials: R
authors.lastname: Schenken
authors.forename: Richard
authors.initials: R
authors.lastname: Blackwell
mesh_terms: D000328:Adult; D005260:Female; D005782:Gels / Q000008:administration & dosage; D006801:Humans; D017137:Nonoxynol / Q000008:administration & dosage*; D017060:Patient Satisfaction; D013089:Spermatocidal Agents / Q000008:administration & dosage; D013488:Suppositories / Q000008:administration & dosage; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014481:United States; D014622:Vaginal Creams, Foams, and Jellies / Q000008:administration & dosage
chemical_list: D005782:Gels; D013089:Spermatocidal Agents; D013488:Suppositories; D014622:Vaginal Creams, Foams, and Jellies; D017137:Nonoxynol