Biomarkers in paediatric research and practice.
Children's health is, to a large extent, a function of their environment. Infectious agents remain the leading cause of death and disability in the world. In contrast, many of the new morbidities--asthma, intellectual impairments, behavioural problems, and cancer--are linked with industrial pollutants or other environmental influences. Our understanding of the risk factors for many diseases is incomplete, but it is widely recognised that disability and death result largely from interactions of environmental factors, broadly defined, and host susceptibility.
Lanphear
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Cincinnati Children's Environmental Health Center, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio, USA. bruce.lanphear@chmcc.org
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D015415:Biomarkers / Q000032:analysis*; D002648:Child; D002657:Child Development / Q000187:drug effects; D002675:Child, Preschool; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D015386:Hazardous Substances / Q000633:toxicity*; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D012307:Risk Factors
D015415:Biomarkers; D015386:Hazardous Substances