Bilateral benign lymphoid hyperplasia of the conjunctiva in a paediatric patient.
A 14-year-old boy presented with a 6-month history of bilateral slowly enlarging conjunctival lesions. There was no associated ocular or systemic symptomatology. Examination revealed bilateral salmon-coloured nodular lesions of the bulbar conjunctiva. The remainder of his ophthalmic and general examinations were normal. Extensive investigation excluded regional or systemic involvement. Excision biopsy of the lesions showed a predominantly mature B lymphocyte infiltrate with immunohistochemistry and flow cytometry consistent with reactive lymphoid hyperplasia. Polymerase chain reaction testing for Epstein-Barr virus was negative. At 2 years follow-up, the patient remained healthy and there was no evidence of recurrence. Benign lymphoid hyperplasia of the conjunctiva with bilateral involvement is extremely rare in children. Only a few case reports have been documented in the literature.
Kim
Peter
P
Department of Ophthalmology, Liverpool Hospital, New South Wales, Australia.
Macken
Peter L
PL
Palfreeman
Simon
S
Rawlinson
William D
WD
Martin
Frank
F
D000293:Adolescent; D001402:B-Lymphocytes / Q000473:pathology; D001706:Biopsy; D003229:Conjunctival Diseases / Q000473:pathology* / Q000601:surgery; D005434:Flow Cytometry; D007839:Functional Laterality; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D016133:Polymerase Chain Reaction; D019310:Pseudolymphoma / Q000473:pathology* / Q000601:surgery