title: Cervical osteotomy in ankylosing spondylitis: evaluation of new developments.
abstract: OBJECTIVE
  Cervical osteotomy can be performed on patients with cervical kyphosis due to ankylosing spondylitis. This study reviews the role of two new developments in cervical osteotomy surgery: internal fixation and transcranial electrical stimulated motor evoked potential monitoring (TES-MEP).
  
  
  METHODS
  From 1999 to 2004, 16 patients underwent a C7-osteotomy with internal fixation. In 11 patients, cervical osteotomy was performed in a sitting position with halo-cast immobilization (group S), five patients underwent surgery in prone position with Mayfield clamp fixation (group P). In group P, longer fusion towards T4-T6 could be obtained that created a more stable fixation. Therefore, post-operative immobilization protocol of group P was simplified from halo-cast to cervical orthosis.
  
  
  RESULTS
  Consolidation was obtained in all patients without loss of correction. Post-operative chin-brow to vertical angle measured 5 degrees (range 0-15). TES-MEP was successfully performed during all surgical procedures. In total, nine neurological events were registered. Additional surgical intervention resulted in recovery of amplitudes in six of nine events. In two patients spontaneous recovery took place. One patient showed no recovery of amplitudes despite surgical intervention and a partial C6 spinal cord lesion occurred.
  
  
  CONCLUSIONS
  We conclude that C7 osteotomy with internal fixation has been shown to be a reliable and stable technique. When surgery is performed the in prone position, distal fixation can be optimally obtained allowing post-operative treatment by cervical orthosis instead of a halo-cast. TES-MEP monitoring has been shown to be a reliable neuromonitoring technique with high clinical relevancy during cervical osteotomy because it allows timely intervention before occurrence of permanent cord damage in a large proportion of the patients.
authors.affiliation: ISSAR (Institiute for Spinal Surgery and Applied Research), Sint Maartenskliniek, Nijmegen, The Netherlands. d.langeloo@maartenskliniek.nl
authors.forename: Danielle D
authors.initials: DD
authors.lastname: Langeloo
authors.forename: Henricus L
authors.initials: HL
authors.lastname: Journee
authors.forename: Paul W
authors.initials: PW
authors.lastname: Pavlov
authors.forename: Marinus
authors.initials: M
authors.lastname: de Kleuver
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002574:Cervical Vertebrae / Q000601:surgery*; D019054:Evoked Potentials, Motor / Q000502:physiology; D005260:Female; D006801:Humans; D016268:Internal Fixators; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods; D010027:Osteotomy / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D013167:Spondylitis, Ankylosing / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome