title: Medial and lateral osteoarthritis of the knee is related to variations of hip and pelvic anatomy.
abstract: OBJECTIVE
  We evaluated if increased risk of combined hip and lateral knee osteoarthritis (OA) could be attributed to anatomical reasons in the hip region resulting in increased abductor moment over the knee.
  
  
  METHODS
  We measured pelvic width, femoral offset, femoral neck length and angle in 29 women with lateral knee OA (13 unilateral, 16 bilateral) and 27 women with bilateral medial OA. Twenty-one of these patients with normal hips (lateral/medial OA of the knee=12/9) and 35 with associated hip OA (lateral/medial OA of the knee=17/18) were evaluated separately. Radiographic examinations in 14 women planned for hip prosthesis because of failures after hip fracture acted as controls.
  
  
  RESULTS
  Patients with lateral OA of the knee had wider pelvis than controls (13.7 mm increased distance between the medial borders of the acetabulum, P=0.001). Patients with medial OA had 11.4mm longer distance from the centre of the femoral head to the centre of the proximal part of the femoral shaft (P=0.005), corresponding to a higher offset. The pelvic and hip anatomy also differed between patients with medial and lateral OA of the knee. In the groups without hip OA, presence of lateral knee OA was associated with a wider pelvis (P=0.009), shorter femoral neck (P=0.02) and Head-Shaft distance (P=0.04). In the groups with OA of the hip associated lateral OA of the knee also implied increased Neck Shaft angle (coxa valga, P=0.008), but there was no difference in pelvic width (P=0.15). We found a shorter lever arm over the hip in lateral knee OA compared to medial knee OA (P=0.02), but not when compared to controls.
  
  
  CONCLUSIONS
  Our findings suggest that occurrence of medial or lateral OA has a biomechanical background originating from pelvis and hip anatomy.
authors.affiliation: Department of Orthopaedics, Sahlgren University Hospital, 413 45 Göteborg, Sweden. weidow@telia.com
authors.forename: J
authors.initials: J
authors.lastname: Weidow
authors.forename: I
authors.initials: I
authors.lastname: Mars
authors.forename: J
authors.initials: J
authors.lastname: Kärrholm
mesh_terms: D005260:Female; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D015207:Osteoarthritis, Hip / Q000473:pathology*; D020370:Osteoarthritis, Knee / Q000473:pathology*; D010384:Pelvic Bones / Q000033:anatomy & histology* / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography; D012307:Risk Factors