Extending Xu's Bayesian model for estimating polygenic effects using markers of the entire genome.
In 2003, Xu obtained remarkably precise estimates of QTL positions despite the many markers simultaneously in his Bayesian model. We extend his model and Gibbs algorithm to ensure a valid posterior distribution and convergence to it, without changing the attractiveness of the method.
ter Braak
Cajo J F
CJ
Biometris, Wageningen University and Research Centre, Wageningen, The Netherlands, 6700 AC. cajo.terbraak@wur.nl
Boer
Martin P
MP
Bink
Marco C A M
MC
D001499:Bayes Theorem; D002874:Chromosome Mapping / Q000379:methods*; D008957:Models, Genetic; D020412:Multifactorial Inheritance / Q000235:genetics*; D040641:Quantitative Trait Loci