[Disorder of bone quality in Paget's disease].
Paget's disease is a localized and progressive disorder of bone, characterized by increased bone remodeling. The increase of bone turnover changed bone quality in Paget's disease. The assessment of bone quality is consisted on two properties of structure and material. Bone quality is evaluated clinically by the bone turnover. Treatment of bisphosphonate in Paget's disease controlled bone turnover. There's a possibility that treatment of bisphosphonate improve not only the property of structure but also that of material. It's hoped that the newer and stronger bisphosphonates play an increasingly important role in the treatment for bone quality of Paget's disease.
Tsurukami
Hiroshi
H
Tsurukami clinic of orthopedic and rheumatology.
D001862:Bone Resorption / Q000188:drug therapy; D001842:Bone and Bones / Q000378:metabolism*; D006801:Humans; D010001:Osteitis Deformans / Q000378:metabolism*