Granulocytic sarcoma of the female genital tract: report of a case with an unusual presentation.
Granulocytic sarcoma of the female genital tract is a rare occurrence. A case of a perimenopausal female is presented who reported with a history of menorrhagia with a lump in the abdomen. A diagnosis of fibroid uterus was made but laparotomy findings were suggestive of inoperable ovarian malignancy with metastases. Postoperatively the patient suddenly became very anemic. Hematological investigations and histopathological reports from ovaries, myometrium, endometrium and intraperitoneal deposits all revealed acute myeloid leukemia. The patient received two cycles of chemotherapy but later succumbed to her disease. Extrauterine causes of menorrhagia should be considered before instituting definitive treatment. Preoperative induction chemotherapy may be more successful in cases of granulocytic sarcoma who tend to have a poor prognosis.
Tripathi
Reva
R
Department of Obstetrics and Gynaecology, Maulana Azad Medical College and Associated Hospitals, New Delhi , India. revatripathi@hotmail.com
Sharma
Babita
B
Chaturvedi
K Uma
KU
Khurana
Neeta
N
Mala
Y M
YM
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D005833:Genital Neoplasms, Female / Q000175:diagnosis* / Q000628:therapy; D013509:Gynecologic Surgical Procedures; D006801:Humans; D010534:Peritoneal Neoplasms / Q000556:secondary* / Q000628:therapy; D023981:Sarcoma, Myeloid / Q000175:diagnosis* / Q000628:therapy