title: [Role of pre-coating in artificial vessel endothelialization].
abstract: OBJECTIVE
  To understand the value of pre-coating in artificial vessel endothelialization.
  
  
  METHODS
  Literature concerning pre-coating in artificial vessel endothelialization was extensively reviewed.
  
  
  RESULTS
  Pre-coating included chemical coatings (collagen, fibronectin, laminin, poly-l-lysin, gelatin and extracellular matrix), pre-clotting (plasma, blood, serum and fibrin glue), chemical bonding (heparin, RGD and lectins) and surface modification. Most of them could enhance the adhesion of the endothelial cells.
  
  
  CONCLUSIONS
  Pre-coating could improve endothelialization, but further research is needed to search for the appropriate concentration and incubation time.
authors.affiliation: Vascular Surgery, the First Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing, 400016, PR China. xiaolittlehappy@yahoo.com
authors.forename: Le
authors.initials: L
authors.lastname: Xiao
authors.forename: De
authors.initials: D
authors.lastname: Shi
mesh_terms: D000818:Animals; D001807:Blood Vessel Prosthesis; D002448:Cell Adhesion / Q000187:drug effects; D020099:Coated Materials, Biocompatible / Q000737:chemistry / Q000494:pharmacology*; D004730:Endothelium, Vascular / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D006801:Humans
chemical_list: D020099:Coated Materials, Biocompatible