Mutagenicity of coenzyme Q10.
Mutagenicity of organically synthesized coenzyme Q10 (CoQ10) was determined by Ames assay in the presence and absence of S9 mix. The tester strains were Salmonella typhimurium TA98, TA100, TA1535, and TA1537, and Escherichia coli WP2 uvr A. CoQ10 displayed no mutagenicity in any tester strain at any dose tested. Therefore, organically synthesized CoQ10 was considered to possess no mutagenicity.
Ikeda
Kazutaka
K
Nisshin Pharma Inc., Chiyoda-ku, Tokyo 101-8441, Japan.
Suzuki
Yoshio
Y
Yoshimjura
Ikuo
I
D003067:Coenzymes; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics; D009152:Mutagenicity Tests; D009153:Mutagens / Q000008:administration & dosage / Q000494:pharmacology*; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics; D014451:Ubiquinone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology*
D003067:Coenzymes; D009153:Mutagens; D014451:Ubiquinone; C024989:coenzyme Q10