title: Feasibility of integrating high-spatial-resolution 3D breath-hold coronary MR angiography with myocardial perfusion and viability examinations.
abstract: The study was institutional review board approved and Health Insurance Portability and Accountability Act compliant. All subjects provided informed consent. Three-dimensional breath-hold coronary magnetic resonance (MR) angiography with use of steady-state free precession was performed in 12 patients up to 20 minutes after 0.2 mmol gadolinium-based contrast material per kilogram of body weight was administered. Within 24 heartbeats, a spatial resolution of up to 1.0 x 1.2 x 2.0 mm was achieved. Sixty-five (82%) of the 79 visualized coronary artery segments had a grade of 3 or 4 on a four-point scale of depiction in which grade 4 indicated excellent depiction. Twenty-seven percent (n = 21) of the 79 segments were assigned a grade of 4; 56% (n = 44), a grade of 3; 16% (n = 13), a grade of 2; and 1% (n = 1), a grade of 1. Coronary MR angiography performed as part of a first-pass myocardial perfusion and viability assessment MR imaging examination is feasible and does not involve additional imaging time.
authors.affiliation: Applied Science Laboratory, GE Healthcare Technologies, Room 110-MRI, 600 N Wolfe St, Baltimore, MD 21287, USA. thomas.foo@med.ge.com
authors.forename: Thomas K F
authors.initials: TK
authors.lastname: Foo
authors.forename: Vincent B
authors.initials: VB
authors.lastname: Ho
authors.forename: Manojkumar
authors.initials: M
authors.lastname: Saranathan
authors.forename: Liu-quan
authors.initials: LQ
authors.lastname: Cheng
authors.forename: Hajime
authors.initials: H
authors.lastname: Sakuma
authors.forename: Dara L
authors.initials: DL
authors.lastname: Kraitchman
authors.forename: Katherine C
authors.initials: KC
authors.lastname: Wu
authors.forename: David A
authors.initials: DA
authors.lastname: Bluemke
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017023:Coronary Angiography / Q000379:methods*; D003326:Coronary Circulation; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012119:Respiration