Calcium metabolism in cows receiving an intramuscular injection of 1,25-dihydroxyvitamin D3 combined with prostaglandin F(2alpha) closely before parturition.
To determine the effect of exogenous 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] combined with induced parturition on calcium (Ca) metabolism, cows received a single intramuscular injection of 1,25(OH)2D3 and prostaglandin F(2alpha) (PGF(2alpha)) closely before calving. Ten late-pregnant, multiparous Holstein cows were assigned to 1,25(OH)2D3 group (five treated with both 1,25(OH)2D3 and PGF(2alpha)) and control group (five treated with PGF(2alpha)). 1,25(OH)2D3 group showed an increase in plasma Ca concentration around parturition, whereas control group revealed a decrease in plasma Ca level. Plasma Ca concentration in 1,25(OH)2D3 group were significantly higher than that in control group during -0.5 to 3 days after parturition.
Yamagishi
Norio
N
Research Center for Animal Hygiene and Food Safety, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan. nori_yamagishi@hotmail.co.jp
Ayukawa
Yu
Y
Lee
Inhyung
I
Oboshi
Kenji
K
Naito
Yoshihisa
Y
D000818:Animals; D002117:Calcitriol / Q000494:pharmacology*; D002118:Calcium / Q000097:blood / Q000378:metabolism*; D002417:Cattle / Q000378:metabolism*; D015237:Dinoprost / Q000494:pharmacology*; D004334:Drug Administration Schedule / Q000662:veterinary; D005260:Female; D007273:Injections, Intramuscular / Q000662:veterinary; D008274:Magnesium / Q000097:blood; D010319:Parturient Paresis / Q000517:prevention & control; D036801:Parturition / Q000097:blood / Q000378:metabolism*; D010758:Phosphorus / Q000097:blood; D011247:Pregnancy; D018709:Statistics, Nonparametric
D010758:Phosphorus; D015237:Dinoprost; D002117:Calcitriol; D008274:Magnesium; D002118:Calcium