Fluorine-18-labeled fluorodeoxyglucose-positron emission tomography studies of acute brainstem Lyme neuroborreliosis [corrected] Case report.
The authors report on a patient suffering from acute Lyme borreliosis who underwent two consecutive [18F]fluorodeoxyglucose-positron emission tomography (FDG-PET) studies demonstrating the course of the disease. The first FDG-PET study revealed markedly increased glucose metabolism in the brainstem, matching exactly the signal abnormalities exhibited on magnetic resonance images and indicating a brainstem tumor. A second PET scan demonstrated no abnormality in this region, thus reflecting clinical remission following antibiotic therapy. Data in the present case indicate that hypermetabolic findings on FDG-PET studies in the brainstem region should be regarded with caution and that neuroborreliosis must be considered as a possible differential diagnosis.
Plotkin
Michail
M
Department of Radiology, Nuclear Medicine and Radiooncology, Campus Virchow-Klinikum, University Hospital Charité, Berlin, Germany. michail.plotkin@charite.de
Hautzel
Hubertus
H
Krause
Bernd Joachim
BJ
Mohr
Stephan
S
Langen
Karl Josef
KJ
Müller
Hans-Wilhelm
HW
D000208:Acute Disease; D001927:Brain Diseases / Q000000981:diagnostic imaging*; D001933:Brain Stem; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D020852:Lyme Neuroborreliosis / Q000000981:diagnostic imaging*; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods*
D019788:Fluorodeoxyglucose F18