title: Three-dimensional stereotactic surface projection study of orthostatic hypotension and brain perfusion image in Parkinson's disease.
abstract: OBJECTIVE
  To compare brain perfusion image using three-dimensional stereotactic surface projection (3D-SSP) analysis of N-isopropyl-p-123I iodoamphetamine (123I-IMP) single photon emission computed tomography (SPECT) between patients with Parkinson's disease with orthostatic hypotension and those without orthostatic hypotension.
  
  
  METHODS
  Fifteen patients with Parkinson's disease and orthostatic hypotension and 13 patients with Parkinson's disease without orthostatic hypotension were studied. We compared brain perfusion image between the two groups by 3D-SSP.
  
  
  RESULTS
  Bilateral anterior cingulate gyrus perfusion of the patients with orthostatic hypotension was significantly decreased compared to that of the patients without orthostatic hypotension.
  
  
  CONCLUSIONS
  The disorder of anterior cingulate gyrus may participate in the autonomic failure in Parkinson's disease.
authors.affiliation: Department of Neurology, Sumitomo Hospital, Nakanoshima, Kita-ku, Osaka, Japan. matsui-hideaki@sumitomo-hp.or.jp
authors.forename: H
authors.initials: H
authors.lastname: Matsui
authors.forename: F
authors.initials: F
authors.lastname: Udaka
authors.forename: T
authors.initials: T
authors.lastname: Miyoshi
authors.forename: N
authors.initials: N
authors.lastname: Hara
authors.forename: A
authors.initials: A
authors.lastname: Tamura
authors.forename: M
authors.initials: M
authors.lastname: Oda
authors.forename: T
authors.initials: T
authors.lastname: Kubori
authors.forename: K
authors.initials: K
authors.lastname: Nishinaka
authors.forename: M
authors.initials: M
authors.lastname: Kameyama
mesh_terms: D000368:Aged; D001342:Autonomic Nervous System Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology; D001921:Brain / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000503:physiopathology; D001931:Brain Mapping / Q000379:methods; D002560:Cerebrovascular Circulation / Q000502:physiology; D005260:Female; D006179:Gyrus Cinguli / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D007024:Hypotension, Orthostatic / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods*; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012984:Software; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
chemical_list: D007457:Iodine Radioisotopes