Blueprinting the regulatory response of Escherichia coli to the urinary tract.
Recent work has shown how comparative genomic and microarray analyses can provide insights into the transcriptional state of uropathogenic Escherichia coli (UPEC) during infection. This study will serve as an important platform from which to identify virulence determinants and the principle mechanisms of adaptation to the urinary tract.
Seed
Patrick C
PC
Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Hultgren
Scott J
SJ
D000222:Adaptation, Physiological; D000818:Animals; D004926:Escherichia coli / Q000235:genetics* / Q000472:pathogenicity / Q000502:physiology; D004927:Escherichia coli Infections / Q000382:microbiology*; D015964:Gene Expression Regulation, Bacterial; D051379:Mice; D020411:Oligonucleotide Array Sequence Analysis; D014158:Transcription, Genetic; D014552:Urinary Tract Infections / Q000382:microbiology*; D037521:Virulence Factors / Q000235:genetics
D037521:Virulence Factors