title: [Spontaneous splenic rupture in a patient with cytomegalovirus infection].
abstract: The Authors report a case of spontaneous splenic rupture in a patient with Cytomegalovirus infection, stress the main characteristics of this infection and describe the mechanism that, during the viral infection, causes morphological and functional alterations of the spleen. The hypersplenism secondary to hyperfunctioning, the formation of immunocomplexes with secondary infarction, mainly of the white pulp, and the disseminated intravascular coagulation are responsible, as in the observed case, of the rupture of splenic capsula. The Authors conclude that the wide diffusion of Cytomegalovirus infection needs the knowledge of all the pathologic signs of this infection to make a timely diagnosis and treatment.
authors.affiliation: Università degli Studi di Messina, Cattedra di Chirurgia dell'Apparato Digerente.
authors.forename: S
authors.initials: S
authors.lastname: Gorgone
authors.forename: C
authors.initials: C
authors.lastname: Praticò
authors.forename: N
authors.initials: N
authors.lastname: Di Pietro
authors.forename: G
authors.initials: G
authors.lastname: Melita
authors.forename: M
authors.initials: M
authors.lastname: Sanò
authors.forename: M
authors.initials: M
authors.lastname: De Luca
authors.forename: C
authors.initials: C
authors.lastname: Minniti
authors.forename: M
authors.initials: M
authors.lastname: Barbuscia
mesh_terms: D000328:Adult; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000601:surgery; D006801:Humans; D008297:Male; D012422:Rupture, Spontaneous; D013156:Splenectomy; D013161:Splenic Rupture / Q000601:surgery / Q000821:virology*; D016896:Treatment Outcome