Cardiac troponin I elevation in paediatric cardiac catheterization.
OBJECTIVE
The aim of this study is to investigate prospectively whether intracardiac catheterization produces myocardial damage in paediatric heart.


METHODS
The study was performed in all patients undergoing diagnostic cardiac catheterization at our institute. A baseline serum sample was drawn before the procedure. The second serum sample was obtained 4-6 hours after the procedure. Cardiac troponin-I and creatine kinase isoenzyme MB fraction levels were determined quantitatively.


RESULTS
Diagnostic cardiac catheterization was performed in 30 patients. There were 17 males and 13 females in the study group. The median age was 12 months (range 1 to 204 months); the median body weight was 8 kilograms (range 2.1 to 45 kilograms). The increase in cardiac troponin I (0.21+/-0.04 ng/ml to 1.16+/-1.40 ng/ml, p<0.05) and creatine kinase isoenzyme MB (26.68+/-7.53 U/L to 41.65+/-22.12 U/L, p< 0.05) levels after the procedure was significant.


CONCLUSIONS
This study shows that serum elevations of cardiac troponin I and creatine kinase isoenzyme MB occur after the most of paediatric diagnostic cardiac catheterization procedures.
Baysal
Tamer
T
Section of Pediatric Cardiology, Department of Pediatrics, Meram Medical Faculty, Selçuk University, Konya, Turkey. tbaysal2@yahoo.com
Oran
Bülent
B
Başpinar
Osman
O
Doğan
Mustafa
M
Karaaslan
Sevim
S
D000293:Adolescent; D006328:Cardiac Catheterization / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D003402:Creatine Kinase / Q000097:blood*; D052279:Creatine Kinase, MB Form; D005260:Female; D006330:Heart Defects, Congenital / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007527:Isoenzymes / Q000097:blood*; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D011446:Prospective Studies; D019210:Troponin I / Q000097:blood*
D007527:Isoenzymes; D019210:Troponin I; D003402:Creatine Kinase; D052279:Creatine Kinase, MB Form