title: Primary neurological manifestations of lung cancer--a retrospective analysis of 8 patients.
abstract: Neurological manifestations are reported in 5 to 10% of cases of lung cancer. We present a series of 216 consecutive patients of lung cancer of which 8 patients presented first with neurological manifestations without overt respiratory symptoms. The present study aimed to identify the number of patients of lung cancer presenting with primary neurological symptoms, the nature of the presentations, and the outcome of these patients among 216 patients who presented over a 2 year period in the Institute of Postgraduate Medical Education and Research, Kolkata. Out of 8 patients, 3 patients presented with seizures, 3 patients with hemiparesis and 2 patients with paraparesis. Thus, 3.7% (8/216) of patients in our series presented with a neurological manifestation. We concluded that primary neurological manifestations are rare in lung cancer. The lungs should be the first site of evaluation in a case of a cerebral metastasis with an unknown primary.
authors.affiliation: Institute of Post Graduate Medical Education and Research, SSKM Hospital, Kolkata.
authors.forename: A
authors.initials: A
authors.lastname: Dasgupta
authors.forename: D
authors.initials: D
authors.lastname: Sarkar
authors.forename: L Geetabali
authors.initials: LG
authors.lastname: Devi
authors.forename: S
authors.initials: S
authors.lastname: Haldar
authors.forename: D
authors.initials: D
authors.lastname: Das
authors.forename: B
authors.initials: B
authors.lastname: Ghosh
authors.forename: C
authors.initials: C
authors.lastname: Dasgupta
authors.forename: S
authors.initials: S
authors.lastname: Basu
authors.forename: A
authors.initials: A
authors.lastname: Ghosh
authors.forename: A
authors.initials: A
authors.lastname: Majumdar
mesh_terms: D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000188:drug therapy / Q000503:physiopathology / Q000556:secondary*; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010291:Paresis / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D012189:Retrospective Studies; D012640:Seizures / Q000209:etiology* / Q000503:physiopathology