[Experimental study on effect of intracranial pressure after different jugular vein ligation in neck dissection].
OBJECTIVE
To investigate the changes of ICP after different jugular vein ligation (JVL), search for a better fashion of JVI, and provide a scientific proof for neck dissection clinically.


METHODS
Forty-eight rabbits were divided into 6 groups randomly that were taken for BC, BEJVL, BIJVL, RJVL, SBJVL and SJVL. Skull puncture technique was employed to get the values of ICP in 0 h, 0.5 h, 1.0 h, 2.0 h, 3.0 h, 4.0 h postoperatively. Necephalic tissue was removed from these rabbits after a week. We observed the quantity and area of glial cell by hematoxylin-eosin stain (HE).


RESULTS
ICP didn't increase in 4.0 h in control groups; After BEJVL, ICP increased slightly and fell to 0 h status within 4.0 h; After BIJVL and RJVL, ICP increased in some degree and decreased apparently in 4.0 h; After SBJVL and SJVL, ICP increased immediately and was lasting hightly after 4.0 h. The quantity and area of glial cell didn't modify apparently in BEJVL, BIJVL and RJVL, but proliferation and hypertrophy of those were observed significantly in SBJVL and SJVL.


CONCLUSIONS
The patients suffered from BEJVL may require no prevent intracranical hypertension. The ones suffered from BIJVL and RJVL should be closely watched for degree of illness. The ones suffered from SBJVL and SJVL must be treated to prevent postoperative complications, such as intracranial hypertasion.
Wu
Fayin
F
Department of Oral and Maxillofacial Surgery, Affiliated Stomatological Hospital, Zunyi Medical College, Zunyi, 563003, China. wfy660505@sina.com
Xie
Wenyan
W
Li
Hualin
H
Chen
Qiong
Q
D000818:Animals; D005260:Female; D019586:Intracranial Hypertension / Q000517:prevention & control; D007427:Intracranial Pressure; D007601:Jugular Veins / Q000601:surgery*; D008026:Ligation; D008297:Male; D037981:Neck Dissection / Q000379:methods*; D011817:Rabbits; D011897:Random Allocation