title: Achievement of behavioral efficacy and improved potency in new heterocyclic analogs of benzofuran H3 antagonists.
authors.affiliation: Department R4MN, AP9A-216, Abbott Laboratories, Global Pharmaceutical Research and Development, 100 Abbott Park Road, Abbott Park, IL 60064-6123, USA. marlon.d.cowart@abbott.com
authors.forename: M
authors.initials: M
authors.lastname: Cowart
authors.forename: R
authors.initials: R
authors.lastname: Faghih
authors.forename: G
authors.initials: G
authors.lastname: Gfesser
authors.forename: M
authors.initials: M
authors.lastname: Curtis
authors.forename: M
authors.initials: M
authors.lastname: Sun
authors.forename: C
authors.initials: C
authors.lastname: Zhao
authors.forename: Y
authors.initials: Y
authors.lastname: Bennani
authors.forename: J
authors.initials: J
authors.lastname: Wetter
authors.forename: K
authors.initials: K
authors.lastname: Marsh
authors.forename: T R
authors.initials: TR
authors.lastname: Miller
authors.forename: K
authors.initials: K
authors.lastname: Krueger
authors.forename: J B
authors.initials: JB
authors.lastname: Pan
authors.forename: K
authors.initials: K
authors.lastname: Drescher
authors.forename: G B
authors.initials: GB
authors.lastname: Fox
authors.forename: T A
authors.initials: TA
authors.lastname: Esbenshade
authors.forename: A A
authors.initials: AA
authors.lastname: Hancock
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001572:Benzofurans / Q000737:chemistry* / Q000494:pharmacology*; D003500:Cyclization; D006633:Histamine Antagonists / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D015394:Molecular Structure; D051381:Rats; D018100:Receptors, Histamine H3 / Q000378:metabolism*
chemical_list: D001572:Benzofurans; D006633:Histamine Antagonists; D018100:Receptors, Histamine H3; C105430:benzofuran