title: Fluorine-18-labeled fluorodeoxyglucose-positron emission tomography studies of acute brainstem Lyme neuroborreliosis [corrected] Case report.
abstract: The authors report on a patient suffering from acute Lyme borreliosis who underwent two consecutive [18F]fluorodeoxyglucose-positron emission tomography (FDG-PET) studies demonstrating the course of the disease. The first FDG-PET study revealed markedly increased glucose metabolism in the brainstem, matching exactly the signal abnormalities exhibited on magnetic resonance images and indicating a brainstem tumor. A second PET scan demonstrated no abnormality in this region, thus reflecting clinical remission following antibiotic therapy. Data in the present case indicate that hypermetabolic findings on FDG-PET studies in the brainstem region should be regarded with caution and that neuroborreliosis must be considered as a possible differential diagnosis.
authors.affiliation: Department of Radiology, Nuclear Medicine and Radiooncology, Campus Virchow-Klinikum, University Hospital Charité, Berlin, Germany. michail.plotkin@charite.de
authors.forename: Michail
authors.initials: M
authors.lastname: Plotkin
authors.forename: Hubertus
authors.initials: H
authors.lastname: Hautzel
authors.forename: Bernd Joachim
authors.initials: BJ
authors.lastname: Krause
authors.forename: Stephan
authors.initials: S
authors.lastname: Mohr
authors.forename: Karl Josef
authors.initials: KJ
authors.lastname: Langen
authors.forename: Hans-Wilhelm
authors.initials: HW
authors.lastname: Müller
mesh_terms: D000208:Acute Disease; D001927:Brain Diseases / Q000000981:diagnostic imaging*; D001933:Brain Stem; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D020852:Lyme Neuroborreliosis / Q000000981:diagnostic imaging*; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods*
chemical_list: D019788:Fluorodeoxyglucose F18