title: Motor cortex excitability after thalamic infarction.
abstract: Transcranial magnetic stimulation was used to map hand muscle representations in the motor cortex of a patient in whom infarction of the sensory thalamus deprived the sensorimotor cortex of sensory input. The threshold for activation of the motor cortex on the affected side was higher and the cortical representational maps of individual muscles were less well defined than those on the normal side. It is concluded that electrophysiological changes in cortical organisation can be demonstrated following withdrawal of, or imbalance in sensory afferent activity to the cerebral cortex in humans.
authors.affiliation: Department of Physiology, The University of Adelaide, Royal Adelaide Hospital, Adelaide SA 5000, Australia.
authors.forename: T S
authors.initials: TS
authors.lastname: Miles
authors.forename: M C
authors.initials: MC
authors.lastname: Ridding
authors.forename: D
authors.initials: D
authors.lastname: McKay
authors.forename: P D
authors.initials: PD
authors.lastname: Thompson
mesh_terms: D000328:Adult; D020520:Brain Infarction / Q000473:pathology* / Q000503:physiopathology*; D004576:Electromyography / Q000379:methods; D019054:Evoked Potentials, Motor / Q000502:physiology / Q000528:radiation effects; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009044:Motor Cortex / Q000503:physiopathology*; D018482:Muscle, Skeletal / Q000503:physiopathology; D013788:Thalamus / Q000473:pathology*; D050781:Transcranial Magnetic Stimulation / Q000379:methods