title: An improved 1H magnetic resonance spectroscopic imaging technique for the human breast: preliminary results.
abstract: The high sensitivity but poor specificity of magnetic resonance imaging for detecting breast cancer has stimulated interest in magnetic resonance spectroscopic imaging (MRSI) as a tool to improve specificity and reduce the number of benign biopsies. The challenge of applying 1H MRSI to the diagnosis of cancer in the human breast is the need for robust lipid suppression and a clinically acceptable acquisition time. We present an improved 1H MRSI technique that uses an independently optimized chemical-shift-selective for lipid suppression and weighted elliptical k-space sampling combined with a Hamming filter for improved sampling efficiency.
authors.affiliation: Department of Radiology, MR Center/Concourse, Harper Hospital, Wayne State University School of Medicine, Detroit, MI 48201, USA. jhu@med.wayne.edu
authors.forename: Jiani
authors.initials: J
authors.lastname: Hu
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Vartanian
authors.forename: Yang
authors.initials: Y
authors.lastname: Xuan
authors.forename: Zahid
authors.initials: Z
authors.lastname: Latif
authors.forename: Renate L
authors.initials: RL
authors.lastname: Soulen
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D002794:Choline / Q000378:metabolism; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA; D002794:Choline