Identification of CTX-M-14 {beta}-lactamase in a Salmonella enterica serovar enteritidis isolate from Japan.
We analyzed the resistance to cefotaxime of a Salmonella enterica serovar Enteritidis isolate from a stool culture of a 4-year-old boy. It produced a beta-lactamase CTX-M-14, encoded by two related R plasmids. The region surrounding the blaCTX-M-14 gene had an original mosaic structure containing insertion sequences (IS26 and IS903D).
Izumiya
Hidemasa
H
Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1-23-1, Shinjuku-ku, Tokyo 162-8640, Japan. izumiya@nih.go.jp
Mori
Kadumi
K
Higashide
Masato
M
Tamura
Kazumichi
K
Takai
Nobuko
N
Hirose
Kenji
K
Terajima
Jun
J
Watanabe
Haruo
H
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002439:Cefotaxime / Q000494:pharmacology*; D018550:Cephalosporin Resistance / Q000235:genetics*; D002675:Child, Preschool; D005243:Feces / Q000382:microbiology; D006801:Humans; D007564:Japan; D008297:Male; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D011815:R Factors / Q000235:genetics; D012480:Salmonella Infections; D012477:Salmonella enteritidis / Q000187:drug effects / Q000201:enzymology*; D017422:Sequence Analysis, DNA; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
D000900:Anti-Bacterial Agents; C456080:beta-lactamase CTX-M-14; D001618:beta-Lactamases; D002439:Cefotaxime