title: Immunology: how do T cells recognize antigen?
abstract: T cells recognize small fragments of microorganisms (antigens) on the surface of other cells using T cell antigen receptors. The mechanism by which these receptors signal into T cells is controversial, but two recent studies provide important new clues.
authors.affiliation: Sir William Dunn School of Pathology, University of Oxford, UK.
authors.forename: Kaushik
authors.initials: K
authors.lastname: Choudhuri
authors.forename: Alice
authors.initials: A
authors.lastname: Kearney
authors.forename: Talitha R
authors.initials: TR
authors.lastname: Bakker
authors.forename: P Anton
authors.initials: PA
authors.lastname: van der Merwe
mesh_terms: D000941:Antigens / Q000276:immunology* / Q000378:metabolism; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology*; D008285:Major Histocompatibility Complex / Q000276:immunology; D018448:Models, Immunological; D011948:Receptors, Antigen, T-Cell / Q000378:metabolism*; D015398:Signal Transduction / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000941:Antigens; D011948:Receptors, Antigen, T-Cell