Human DNA repair genes, 2005.
An updated inventory of about 150 human DNA repair genes is described. The compilation includes genes encoding DNA repair enzymes, some genes associated with cellular responses to DNA damage, and other genes associated with genetic instability or sensitivity to DNA damaging agents. The updated human DNA repair genes table (http://www.cgal.icnet.uk/DNA_Repair_Genes.htmlhttp://www.cgal.icnet.uk/DNA_Repair_Genes.html) is a research and reference tool that directly links to several databases: Gene Cards, Online Mendelian Inheritance in Man, the NCBI MapViewer for chromosome position, and the NCBI Entrez database for the reference nucleotide sequence. This article discusses the approximately 25 genes added, since the original version of the table was first produced in 2001, and some other revisions.
Wood
Richard D
RD
University of Pittsburgh Cancer Institute, Hillman Cancer Center, Research Pavilion, Suite 2.6, 5117 Centre Avenue, Pittsburgh, PA 15213, USA. rdwood@pitt.edu
Mitchell
Michael
M
Lindahl
Tomas
T
D002843:Chromatin / Q000737:chemistry; D002877:Chromosomes, Human; D004249:DNA Damage; D004260:DNA Repair / Q000235:genetics*; D004259:DNA-Directed DNA Polymerase / Q000378:metabolism; D005199:Fanconi Anemia / Q000235:genetics; D006801:Humans; D011995:Recombination, Genetic
D002843:Chromatin; D004259:DNA-Directed DNA Polymerase