title: Development of a shape memory alloy multiple-point injector for chemotherapy.
abstract: A medical needle is described that allows injection to take place at multiple sites through a single stab wound. This is achieved by extruding multiple, thin, and curved internal needles from a larger, straight, outer needle. The development and finite element modelling of the shape memory alloy (SMA) inner needles is presented in this paper. A non-linear elastic element model was used in this process to allow for the non-linear properties of the alloy and the large deformations that occur. The model provided maximum strain values and penetration forces for the inner needles. The deformation force on the tip of the needle was measured against displacement to confirm the predicted penetration force. Applications for the device include the treatment of liver cancer by direct injection of alcohol into the tumours.
authors.affiliation: Centre for Biomedical Engineering, School of Engineering, University of Surrey, Guildford, UK. w.xu@surrey.ac.uk
authors.forename: W
authors.initials: W
authors.lastname: Xu
authors.forename: T G
authors.initials: TG
authors.lastname: Frank
authors.forename: A
authors.initials: A
authors.lastname: Cuschieri
mesh_terms: D000497:Alloys; D017076:Computer-Aided Design; D004358:Drug Therapy / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D015552:Injections, Intralesional / Q000295:instrumentation* / Q000379:methods; D008845:Microinjections / Q000295:instrumentation* / Q000379:methods; D008904:Miniaturization / Q000379:methods; D009339:Needles; D013314:Stress, Mechanical
chemical_list: D000497:Alloys