title: [Effects of different light-dark cycle on learning and memory in mice].
abstract: OBJECTIVE
  To study the effect of different light-dark cycles on learning and memory in mice.
  
  
  METHODS
  Seventy-two ICR mice were raised under different light-dark cycles including LD 5h/5h, LD 12h/12h and LD 22h/22h for 6 weeks. The locomotor activity was recorded continuously. Morris water-maze task was used as the judging criteria for spatial learning and memory.
  
  
  RESULTS
  The locomotor activity rhythm was consistent with the light-dark cycle. The period of light-dark cycle shorter than 24 h such as 10 h could effect on the ability of learning and memory in mice.
  
  
  CONCLUSIONS
  The short period of light-dark cycle can improve the ability of learning and memory in mice.
authors.forename: Yan-you
authors.initials: YY
authors.lastname: Liu
authors.forename: Bo
authors.initials: B
authors.lastname: Yang
authors.forename: Zhou
authors.initials: Z
authors.lastname: Jiang
authors.forename: Li
authors.initials: L
authors.lastname: Guo
authors.forename: Yue-qi
authors.initials: YQ
authors.lastname: Wang
authors.forename: Zheng-rong
authors.initials: ZR
authors.lastname: Wang
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000528:radiation effects*; D003624:Darkness; D007858:Learning / Q000528:radiation effects*; D008027:Light; D018782:Maze Learning / Q000528:radiation effects; D008568:Memory / Q000528:radiation effects*; D051379:Mice; D008813:Mice, Inbred ICR; D017440:Photoperiod; D012153:Retention, Psychology / Q000528:radiation effects