title: 1H and 13C NMR spectral assignment of androstane derivatives.
abstract: (1)H and (13)C NMR spectroscopic data for 5alpha-androstanes and halo-5alpha-androstanes with different substituents at positions C-3, C-9, C-11 and C-17 were examined and assigned by a combination of 1D and 2D NMR experiments. The substituent effects on the (13)C chemical shifts were compared with those of epi-androsterone, used as a reference compound. The coupling constants (n)J((19)F,(13)C) were measured for compounds 6, 8, 11 and 14.
authors.affiliation: Centro de Química Farmacéutica, Apartado Postal 16042, Ciudad de La Habana, Cuba.
authors.forename: Ariadna
authors.initials: A
authors.lastname: Fuente
authors.forename: Mayra
authors.initials: M
authors.lastname: Reyes
authors.forename: Yoanna M
authors.initials: YM
authors.lastname: Alvarez
authors.forename: José A
authors.initials: JA
authors.lastname: Ruiz
authors.forename: Hermán
authors.initials: H
authors.lastname: Vélez
authors.forename: Omar
authors.initials: O
authors.lastname: Viñas-Bravo
authors.forename: Sara
authors.initials: S
authors.lastname: Montiel-Smith
authors.forename: Socorro
authors.initials: S
authors.lastname: Meza-Reyes
authors.forename: Jesús
authors.initials: J
authors.lastname: Sandoval-Ramírez
mesh_terms: D000731:Androstanes / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods* / Q000592:standards*; D008968:Molecular Conformation; D012016:Reference Values
chemical_list: D000731:Androstanes