Research progress on Helicobacter pylori outer membrane protein.
Helicobacter pylori (H pylori), one of the most common bacterial pathogens on human beings, colonizes the gastric mucosa. In its 95 paralogous gene families, there is a large outer membrane protein (OMP) family. It includes 32 members. These OMP are important for the diagnosis, protective immunity, pathogenicity of H pylori and so on. They are significantly associated with high H pylori density, the damage of gastric mucosa, high mucosal IL-8 levels and severe neutrophil infiltration. We introduce their research progress on pathogenicity.
Shao
Shi-He
SH
Department of Medical Microbiology and Parasitology, Medical Technology College, Jiangsu University, Zhenjiang 212001, Jiangsu Province, China. ljxwl123@163.com
Wang
Hua
H
Chai
Shun-Gen
SG
Liu
Li-Mei
LM
D001425:Bacterial Outer Membrane Proteins / Q000502:physiology*; D005753:Gastric Mucosa / Q000382:microbiology; D005756:Gastritis / Q000382:microbiology; D016481:Helicobacter Infections / Q000382:microbiology / Q000503:physiopathology; D016480:Helicobacter pylori / Q000472:pathogenicity* / Q000502:physiology*; D006801:Humans; D010437:Peptic Ulcer / Q000382:microbiology; D013274:Stomach Neoplasms / Q000382:microbiology
D001425:Bacterial Outer Membrane Proteins