Indole alkaloids from the leaves of Philippine Alstonia scholaris.
The first seco-uleine alkaloids, manilamine (1) (18-hydroxy-19,20-dehydro-7,21-seco-uleine) and N4-methyl angustilobine B (2), were isolated from the (pH 5) alkaloid extract of Philippine Alstonia scholaris leaves together with the known indole alkaloids 19,20-(E)-vallesamine (3), angustilobine B N4-oxide (4), 20(S)-tubotaiwine (5), and 6,7-seco-angustilobine B (6). The structure of the alkaloids was established from MS and NMR experiments.
Macabeo
Allan Patrick G
AP
Phytochemistry Laboratory, Research Center for the Natural Sciences, Thomas Aquinas Research Complex, University of Santo Tomas, Espana St., Manila 1008, Philippines.
Krohn
Karsten
K
Gehle
Dietmar
D
Read
Roger W
RW
Brophy
Joseph J
JJ
Cordell
Geoffrey A
GA
Franzblau
Scott G
SG
Aguinaldo
Alicia M
AM
D031051:Alstonia / Q000737:chemistry*; D026121:Indole Alkaloids / Q000737:chemistry*; D008956:Models, Chemical; D015394:Molecular Structure; D010679:Philippines; D018515:Plant Leaves / Q000737:chemistry*
D026121:Indole Alkaloids