Detection of qnr in clinical isolates of Escherichia coli from Korea.
qnr was detected in 2 of 260 Escherichia coli clinical isolates collected from a Korean hospital during the period 2001 to 2003. The two strains were not clonally related. qnr was located in In4 family class 1 integrons of original structure, downstream of orf513 and upstream from another resistance gene (dfrA3b) and a gene of unknown function (orf105). Transfer of the qnr determinant by conjugation could be detected from only one strain.
Jeong
Jin-Yong
JY
Division of Infectious Diseases, Asan Medical Center and Asan Institute for Life Sciences, University of Ulsan College of Medicine, 388-1 Pungnap-dong, Songpa-gu, Seoul 138-736, Korea.
Yoon
Hyun Jung
HJ
Kim
Eun Sil
ES
Lee
Yoola
Y
Choi
Sang-Ho
SH
Kim
Nam Joong
NJ
Woo
Jun Hee
JH
Kim
Yang Soo
YS
D000890:Anti-Infective Agents / Q000494:pharmacology; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000382:microbiology*; D029968:Escherichia coli Proteins / Q000235:genetics*; D006801:Humans; D032023:Integrons / Q000235:genetics; D007723:Korea; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D015363:Quinolones / Q000494:pharmacology; D017422:Sequence Analysis, DNA
D000890:Anti-Infective Agents; D029968:Escherichia coli Proteins; C485384:Qnr protein, E coli; D015363:Quinolones