[Role of pre-coating in artificial vessel endothelialization].
OBJECTIVE
To understand the value of pre-coating in artificial vessel endothelialization.


METHODS
Literature concerning pre-coating in artificial vessel endothelialization was extensively reviewed.


RESULTS
Pre-coating included chemical coatings (collagen, fibronectin, laminin, poly-l-lysin, gelatin and extracellular matrix), pre-clotting (plasma, blood, serum and fibrin glue), chemical bonding (heparin, RGD and lectins) and surface modification. Most of them could enhance the adhesion of the endothelial cells.


CONCLUSIONS
Pre-coating could improve endothelialization, but further research is needed to search for the appropriate concentration and incubation time.
Xiao
Le
L
Vascular Surgery, the First Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing, 400016, PR China. xiaolittlehappy@yahoo.com
Shi
De
D
D000818:Animals; D001807:Blood Vessel Prosthesis; D002448:Cell Adhesion / Q000187:drug effects; D020099:Coated Materials, Biocompatible / Q000737:chemistry / Q000494:pharmacology*; D004730:Endothelium, Vascular / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D006801:Humans
D020099:Coated Materials, Biocompatible