title: Metal-enhanced fluorescence using anisotropic silver nanostructures: critical progress to date.
abstract: In this critical and timely review, the effects of anisotropic silver nanostructures on the emission intensity and photostability of a key fluorophore that is frequently used in many biological assays is examined. The silver nanostructures consist of triangular, rod-like, and fractal-like nanoparticles of silver deposited on conventional glass substrates. The close proximity to silver nanostructures results in greater intensity and photostability of the fluorophore than for fluorophores solely deposited on glass substrates. These new anisotropic silver nanostructure-coated surfaces show much more favorable effects than silver island films or silver colloid-coated substrates. Subsequently, the use of metal-enhanced fluorescence (MEF) for biosensing applications is discussed.
authors.affiliation: Laboratory for Advanced Medical Plasmonics, Medical Biotechnology Center, Institute of Fluorescence, University of Maryland Biotechnology Institute, 725 West Lombard Street, Baltimore, MD 21201, USA.
authors.forename: Kadir
authors.initials: K
authors.lastname: Aslan
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Lakowicz
authors.forename: Chris D
authors.initials: CD
authors.lastname: Geddes
mesh_terms: D016880:Anisotropy; D015374:Biosensing Techniques / Q000379:methods; D049329:Nanostructures / Q000737:chemistry*; D012680:Sensitivity and Specificity; D012834:Silver / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000379:methods; D013499:Surface Properties; D013997:Time Factors
chemical_list: D012834:Silver