title: Synthesis of a photoactivatable probe of the anandamide re-uptake.
abstract: To date, despite extensive investigations, full understanding of the endocannabinoid system remains elusive; in particular, anandamide cellular uptake is a current controversial topic. An iodo-arylazido probe was synthesized from commercially available azelaic acid monomethyl ester, in order to shed light on the anandamide transport process.
authors.affiliation: UMR CNRS 5074, Faculty of Pharmacy, 15 avenue Charles Flahault, BP 14491, 34093 Montpellier 5, France.
authors.forename: Laurence
authors.initials: L
authors.lastname: Balas
authors.forename: Malik
authors.initials: M
authors.lastname: Hellal
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Rossi
authors.forename: Thierry
authors.initials: T
authors.lastname: Durand
mesh_terms: D001095:Arachidonic Acids / Q000737:chemistry* / Q000378:metabolism*; D001593:Benzyl Compounds / Q000737:chemistry*; D063388:Endocannabinoids; D019995:Laboratory Chemicals / Q000138:chemical synthesis / Q000737:chemistry; D015394:Molecular Structure; D010777:Photochemistry; D053284:Polyunsaturated Alkamides
chemical_list: D001095:Arachidonic Acids; D001593:Benzyl Compounds; D063388:Endocannabinoids; D019995:Laboratory Chemicals; C474344:OMDM-1 cpd; D053284:Polyunsaturated Alkamides; C078814:anandamide