title: The relation between resolution measurements and numbers of retinal ganglion cells in the same human subjects.
abstract: Limiting factors of resolution have previously only been investigated by using resolution data and retinal ganglion cell spacing data from different individuals. We report on our unique opportunity to study the intra-individual relationship in three human subjects between retinal ganglion cell separations and resolution thresholds, measured with high-pass resolution perimetry. Our data show that resolution is directly proportional to half the midget population, in accordance with the hypothesis that a dichotomous midget ON/OFF population mediates resolution.
authors.affiliation: Institute of Clinical Neuroscience, Department of Ophthalmology, Sahlgrenska Academy, Göteborg University, SU/Mölndal, 431 80 Mölndal, Sweden. zoran@oft.gu.se
authors.forename: Zoran
authors.initials: Z
authors.lastname: Popovic
authors.forename: Johan
authors.initials: J
authors.lastname: Sjöstrand
mesh_terms: D000368:Aged; D002469:Cell Separation; D005134:Eye Neoplasms / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D011601:Psychophysics; D012044:Regression Analysis; D012165:Retinal Ganglion Cells / Q000473:pathology / Q000502:physiology*; D012684:Sensory Thresholds / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology*; D058609:Visual Field Tests / Q000379:methods; D014796:Visual Perception / Q000502:physiology*