Synthesis and bioactivity of some new N-aryl/alkyl/cyclohexyl-N'-(2,3-dihydro-2-oxo-4H-benz[e][1,3,2]oxazaphosphorin-2-yl) ureas.
Several new substituted oxazaphosphorinyl urea derivatives of the type RR'P(O)NHC(O)NHR'' were synthesized from alpha-(3-chloro-4-fluoroanilino)-o-cresol by reaction with chlorides of aryl/alkyl/cyclohexyl carbamidophosphoric acids in the presence of triethylamine at 0-50 degrees C. Their significant insecticidal and antimicrobial activity and promotion of Rhizobium bacteria growth in the soil without effect on the host tissue suggests their possible commercial application as ecofriendly pesticides and antimicrobial agents.
Kiran
Y B
YB
Department of Chemistry, Sri Venkateswara University, Tirupati, India.
Gunasekar
D
D
Devendranath Reddy
C
C
Suresh Reddy
C
C
Tran
Kevin
K
Le
Thanh
T
Berlin
K Darrell
KD
Srinivasan
S
S
Charitha Devi
M
M
D000528:Alternaria / Q000187:drug effects; D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000494:pharmacology; D001234:Aspergillus niger / Q000187:drug effects; D001412:Bacillus subtilis / Q000187:drug effects; D012831:Bombyx / Q000187:drug effects; D001517:Coleoptera / Q000187:drug effects; D007306:Insecticides / Q000138:chemical synthesis / Q000494:pharmacology; D015394:Molecular Structure; D010063:Ovum / Q000187:drug effects; D012231:Rhizobium / Q000187:drug effects; D014508:Urea / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D007306:Insecticides; D014508:Urea