A HPLC method for the simultaneous determination of seven anthracyclines.
A HPLC method has been developed for the determination of epirubicin hydrochloride, doxorubicin hydrochloride and idarubicin hydrochloride in the presence of four other anthracyclines. This method ensures the rapid determination of seven anthracyclines. It is simple and rapid and does not require any preliminary treatment of the sample. The method was fully validated.
Badea
Irinel
I
Department of Analytical Chemistry, University of Bucharest, Romania. irinel_badea@yahoo.com
Lazăr
Lelia
L
Moja
Dana
D
Nicolescu
Daniela
D
Tudose
Aurel
A
D018943:Anthracyclines / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D015203:Reproducibility of Results
D018943:Anthracyclines; D004364:Pharmaceutical Preparations