Determination of cymoxanil in drinking water and soil using high-performance liquid chromatography.
We describe a method for determination of cymoxanil, 1-2-cyano-2-methoxy(iminoacetyl)-3-ethylurea, in drinking water and in soil, using reversed-phase HPLC with UV detection at 240 nm and a mobile phase of acetonitrile-water (30:70, v/v). Fortified water samples (1.0 L) were extracted with solid-phase extraction on Strata X. Soil samples (20 g) were extracted with acetone and the extracts were transferred onto Strata C18E. The recoveries of cymoxanil from water and soil samples were over 85% for each fortification level. The RDS were within the range 1.7-4.1% for water and 0.9-1.2% for soil samples. After optimization of the extraction and separation conditions, the method was validated.
Fidente
Paola
P
Dipartimento di Chimica Farmaceutica e Tossicologica, Università degli Studi di Napoli Federico II, via D. Montesano 49, 80131 Napoli, Italy.
Di Giovanni
Carmen
C
Seccia
Serenella
S
Morrica
Patrizia
P
D000081:Acetamides / Q000032:analysis*; D005591:Chemical Fractionation / Q000379:methods; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D015203:Reproducibility of Results; D012989:Soil Pollutants / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000032:analysis*; D014881:Water Supply / Q000032:analysis
D000081:Acetamides; D012989:Soil Pollutants; D014874:Water Pollutants, Chemical; C025644:2-cyano-N-((ethylamino)carbonyl)-2-(methoxyimino)acetamide