Assay of rotenone in river water by high-throughput tandem mass spectrometry and multiple-reaction monitoring methodology.
The high-throughput analytical approach proposed for the assay of rotenone in lake and river waters presented here is based on atmospheric pressure chemical ionization (APCI) multiple-reaction monitoring (MRM) methodology whereby the analyte and internal standard solutions are directly analyzed, without any previous chromatographic separation. The very good accuracy is obtained by the critical choice of a reference compound that shows gas-phase chemistry similar to that of the analyte, by producing the same product ions selected for the MRM-based assay.
Di Donna
Leonardo
L
Dipartimento di Chimica, Università della Calabria, cubo 12/C, I-87030 Arcavacata di Rende CS, Italy.
Mazzotti
Fabio
F
Sindona
Giovanni
G
Tagarelli
Antonio
A
D001272:Atmosphere; D004784:Environmental Monitoring / Q000379:methods*; D007306:Insecticides / Q000032:analysis*; D015203:Reproducibility of Results; D045483:Rivers / Q000737:chemistry*; D012402:Rotenone / Q000032:analysis*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000032:analysis*
D007306:Insecticides; D014874:Water Pollutants, Chemical; D012402:Rotenone