Hepatobiliary phaeohyphomycosis with secondary biliary cirrhosis.
We report a case of systemic phaeohyphomycosis in a 13-year old girl. The clinical presentation was with fever, weight loss, cholestatic jaundice with hepatosplenomegaly and generalized lymphadenopathy. The patient was diagnosed initially as tuberculous adenitis and was on antituberculous therapy, but with worsening of symptoms. Lymph node and liver biopsy showed granuloma with fungal hyphae suggestive of phaeohyphomycosis. The patient responded to antifungal therapy. Later she developed secondary biliary cirrhosis with cholangitis due to long stricture of the common bile duct and common hepatic duct requiring biliary stenting. To the best of our knowledge, this is the first report on phaeohyphomycosis causing biliary cirrhosis in the English lilterature.
Harish
K
K
Departments of Gastroenterology and Pathology, Medical College Hospital, Kozhikode 673 008, Kerala.
Harikumar
R
R
Aravindan
K P
KP
Varghese
Thomas
T
D002648:Child; D002779:Cholestasis / Q000175:diagnosis* / Q000382:microbiology* / Q000628:therapy; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis* / Q000382:microbiology* / Q000628:therapy; D009181:Mycoses / Q000175:diagnosis* / Q000628:therapy