title: Protein microarray for profiling antibody responses to Yersinia pestis live vaccine.
abstract: A protein microarray representing 149 Yersinia pestis proteins was developed to profile antibody responses in EV76-immunized rabbits. Antibodies to 50 proteins were detected. There are 11 proteins besides F1 and V antigens to which the predominant antibody response occurred, and these proteins show promise for further evaluation as candidates for subunit vaccines and/or diagnostic antigens.
authors.affiliation: Laboratory of Analytical Microbiology, National Center for Biomedical Analysis, Army Center for Microbial Detection and Research, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
authors.forename: Bei
authors.initials: B
authors.lastname: Li
authors.forename: Lingxiao
authors.initials: L
authors.lastname: Jiang
authors.forename: Qifeng
authors.initials: Q
authors.lastname: Song
authors.forename: Junxin
authors.initials: J
authors.lastname: Yang
authors.forename: Zeliang
authors.initials: Z
authors.lastname: Chen
authors.forename: Zhaobiao
authors.initials: Z
authors.lastname: Guo
authors.forename: Dongsheng
authors.initials: D
authors.lastname: Zhou
authors.forename: Zongmin
authors.initials: Z
authors.lastname: Du
authors.forename: Yajun
authors.initials: Y
authors.lastname: Song
authors.forename: Jin
authors.initials: J
authors.lastname: Wang
authors.forename: Hongxia
authors.initials: H
authors.lastname: Wang
authors.forename: Shouyi
authors.initials: S
authors.lastname: Yu
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.forename: Ruifu
authors.initials: R
authors.lastname: Yang
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D000942:Antigens, Bacterial / Q000276:immunology; D007114:Immunization; D010931:Plague Vaccine / Q000276:immunology*; D040081:Protein Array Analysis; D011817:Rabbits; D015010:Yersinia pestis / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D010931:Plague Vaccine