title: Extracorporeal life support: history and new directions.
abstract: This review recounts the development of extracorporeal life support (ECLS, ECMO) from the laboratory and early clinical trials to routine clinical application. Lessons from neonatal ECMO have led to better understanding of neonatal lung physiology, improved methods of treatment, and application of ECLS to other patient populations.
authors.affiliation: University of Michigan Medical Center, 1500 E. Medical Center Drive, Taubman Center 2920, Ann Arbor, MI 48109-0331, USA. robbar@umich.edu
authors.forename: Robert H
authors.initials: RH
authors.lastname: Bartlett
mesh_terms: D005112:Extracorporeal Circulation / Q000266:history* / Q000639:trends; D015199:Extracorporeal Membrane Oxygenation / Q000266:history / Q000639:trends; D049673:History, 20th Century; D006801:Humans; D007231:Infant, Newborn; D008567:Membranes, Artificial; D012131:Respiratory Insufficiency / Q000628:therapy
chemical_list: D008567:Membranes, Artificial