title: Use of novel, non-imidazole inverse agonist radioligands to define histamine H3 receptor pharmacology.
authors.affiliation: Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL 60064, USA. Tim.Esbenshade@Abbott.com
authors.forename: T A
authors.initials: TA
authors.lastname: Esbenshade
authors.forename: B B
authors.initials: BB
authors.lastname: Yao
authors.forename: D G
authors.initials: DG
authors.lastname: Witte
authors.forename: T L
authors.initials: TL
authors.lastname: Carr
authors.forename: R
authors.initials: R
authors.lastname: Sharma
authors.forename: J L
authors.initials: JL
authors.lastname: Baranowski
authors.forename: K M
authors.initials: KM
authors.lastname: Krueger
authors.forename: T R
authors.initials: TR
authors.lastname: Miller
authors.forename: B W
authors.initials: BW
authors.lastname: Surber
authors.forename: R
authors.initials: R
authors.lastname: Faghih
authors.forename: A A
authors.initials: AA
authors.lastname: Hancock
mesh_terms: D000818:Animals; D001713:Biphenyl Compounds / Q000737:chemistry / Q000494:pharmacology*; D002460:Cell Line; D017442:Histamine Agonists / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D007093:Imidazoles / Q000737:chemistry; D015394:Molecular Structure; D010879:Piperazines / Q000737:chemistry / Q000494:pharmacology*; D011869:Radioligand Assay; D051381:Rats; D018100:Receptors, Histamine H3 / Q000378:metabolism*
chemical_list: C489829:A349821; D001713:Biphenyl Compounds; D017442:Histamine Agonists; D007093:Imidazoles; C475226:N-(2-(4-(3-(4-(cyclopropylcarbonyl)phenoxy)propyl)-1-piperazinyl)-1-methyl-2-oxoethyl)-2-furamide; D010879:Piperazines; D018100:Receptors, Histamine H3; C029899:imidazole