Congenital lupus erythematosus: case report and review of the literature.
Congenital presentation of neonatal lupus erythematous is very rare. We describe an infant who had congenital neonatal lupus erythematosus with atrophic lesions on the face and scarring lesions on the trunk. All radiologic, virologic, and hematologic assays were normal. Skin biopsy specimen and immunofluorescence findings led us to suspect neonatal lupus, a diagnosis confirmed by positivity for anti-Sjörgen syndrome and antinuclear antibodies both in the child and her mother. In this infant, skin manifestations represented the stable and irreversible outcome of an inflammatory stage that occurred during pregnancy.
Diociaiuti
Andrea
A
Unit of Dermatology, Ospedale Pediatrico Bambino Gesù, Rome, Italy.
Paone
Cristina
C
Giraldi
Loredana
L
Paradisi
Mauro
M
El Hachem
Maya
M
D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008178:Lupus Erythematosus, Cutaneous / Q000151:congenital* / Q000175:diagnosis