title: The total synthesis of spectinabilin and its biomimetic conversion to SNF4435C and SNF4435D.
abstract: [reaction: see text] A short synthesis of (+/-)-spectinabilin via a trans-selective Suzuki coupling and subsequent Negishi-type methylation, and its biomimetic conversion to (+/-)-SNF4435C and (+/-)-SNF4435D is described.
authors.affiliation: Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA, United Kingdom.
authors.forename: Mikkel F
authors.initials: MF
authors.lastname: Jacobsen
authors.forename: John E
authors.initials: JE
authors.lastname: Moses
authors.forename: Robert M
authors.initials: RM
authors.lastname: Adlington
authors.forename: Jack E
authors.initials: JE
authors.lastname: Baldwin
mesh_terms: D018716:Molecular Mimicry; D015394:Molecular Structure; D009574:Nitro Compounds / Q000737:chemistry*; D011753:Pyrones / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D009574:Nitro Compounds; D011753:Pyrones; C435067:SNF 4435C; C435066:SNF 4435D; C508401:spectinabilin