Severe CD8 deficiency in a child with miliary tuberculosis.
This report described a 6-month-old boy who presented with miliary tuberculosis and severe CD8 deficiency, which is most likely secondary to miliary tuberculosis since his CD8 was back to normal 6 month after therapy and primary CD8 deficiency, (ZAP 70 defect) was ruled out. To our knowledge this is the first paediatric case reported with severe CD8 deficiency secondary to miliary TB.
Kordy
Faisal Nayel
FN
Department of Pediatrics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Al-Jumaah
Sulaiman
S
Al-Ghonaim
Abdulaziz
A
D000995:Antitubercular Agents / Q000627:therapeutic use; D016827:CD8 Antigens / Q000097:blood* / Q000276:immunology; D006801:Humans; D007223:Infant; D008297:Male; D016511:Severe Combined Immunodeficiency / Q000097:blood / Q000209:etiology*; D014391:Tuberculosis, Miliary / Q000150:complications* / Q000188:drug therapy / Q000276:immunology
D000995:Antitubercular Agents; D016827:CD8 Antigens