Genetics of cardiological disorders.
Information generated by work on the human genome means that we now understand the genetic basis of many of the cardiac anomalies that present in the fetal and neonatal periods. This allows for an earlier and more definitive diagnosis of an underlying syndrome, although it does not replace the need for an accurate recognition of clinical signs. The implications of this new information are considered in the context of some of the more frequently encountered conditions with cardiac associations.
Manning
Nicky
N
Department of Paediatric Cardiology (Fetal Cardiology), John Radcliffe Hospital, Oxford, UK. nicky.manning@orh.nhs.uk
Kaufman
Louise
L
Roberts
Philip
P
D000013:Congenital Abnormalities / Q000235:genetics; D030342:Genetic Diseases, Inborn / Q000235:genetics; D006330:Heart Defects, Congenital / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn