title: In Vitro antioxidant effect and inhibition of alpha-amylase of two varieties of Amaranthus caudatus seeds.
abstract: This study reports on the biological properties, antioxidant and antidiabetic, of two varieties of Amaranthus caudatus seeds, Oscar blanco and Victor red. Oil, squalene and phenolic contents were also determined. Seeds of both investigated varieties were found to possess very different levels of squalene (2.2% in Oscar blanco variety and 7.5% in Victor red variety). Although the antioxidant activity of A. caudatus var. Oscar blanco and A. caudatus var. Victor red statistically did not differ significantly from each other (IC50 values of ethyl acetate extracts were 0.50 mg/ml and 0.62 mg/ml, respectively), significant differences were noticed in relation to antidiabetic activity (inhibition of alpha-amylase, EC 3.2.1.1) of methanolic extracts that showed 50.5% for A. caudatus var. Oscar blanco and 28% for A. caudatus var. Victor red at concentration of 25 microg/ml.
authors.affiliation: Department of Pharmaceutical Sciences, University of Calabria, Rende, Italy. filomena.conforti@unical.it
authors.forename: Filomena
authors.initials: F
authors.lastname: Conforti
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Statti
authors.forename: Monica Rosa
authors.initials: MR
authors.lastname: Loizzo
authors.forename: Gianni
authors.initials: G
authors.lastname: Sacchetti
authors.forename: Ferruccio
authors.initials: F
authors.lastname: Poli
authors.forename: Francesco
authors.initials: F
authors.lastname: Menichini
mesh_terms: D027721:Amaranthus; D000818:Animals; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology*; D002417:Cattle; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology; D011480:Protease Inhibitors / Q000302:isolation & purification / Q000494:pharmacology; D012639:Seeds; D000516:alpha-Amylases / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: D000975:Antioxidants; D010936:Plant Extracts; D011480:Protease Inhibitors; D000516:alpha-Amylases