[Prognostic value of the immunohistochemical expresion of protein Rb in epidermoid carcinoma of the larynx].
In this paper we carried out an immunohistochemical study of protein Rb (G3-245) expression in a series of 195 patients with laryngeal carcinoma that were diagnosticated, treated and followed at the Department of Otolaryngology at "Virgen de la Salud" Hospital (Toledo, Spain) for a time of 5 years. In the cases with lymph node metastasis we also studied Rb expression at this level. Furthermore we have analysed the value of Rb expression as a prognostic factor (tumor recurrence, deads due to cancer and survival) and we evaluate the relationship between Rb expression and other clinic and pathologic parameters.
García Lozano
M C
MC
Servicio ORL, Hospital Gutiérrez Ortega, Valdepeñas. cjangela@castillalamancha.es
Orradre Romero
J L
JL
Sánchez Carrión
S
S
Menéndez Loras
L M
LM
Jiménez Antolín
J
J
Piris Pinilla
M A
MA
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000378:metabolism* / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007822:Laryngeal Neoplasms / Q000378:metabolism* / Q000473:pathology*; D011379:Prognosis; D016160:Retinoblastoma Protein / Q000096:biosynthesis*
D016160:Retinoblastoma Protein