title: Primary hypothyroidism in a 12-year-old girl with a suprasellar pituitary mass: rapid regression after thyroid replacement therapy: case report.
abstract: The authors report on a 12-year-old girl with a suprasellar mass and primary hypothyroidism in whom the lesion promptly regressed following initiation of thyroid replacement therapy. Based on this experience, it is suggested that secondary pituitary hyperplasia be included in the differential diagnostic considerations of a suprasellar lesion in a child and that resolution of the hyperplasia may occur in a matter of weeks rather than months as previously reported.
authors.affiliation: Departments of Neurological Surgery and Radiology, Washington University School of Medicine, Mallinckrodt Institute of Radiology, St Louis Children's Hospital, St Louis, Missouri, USA.
authors.forename: William W
authors.initials: WW
authors.lastname: Ashley
authors.forename: Jeffrey G
authors.initials: JG
authors.lastname: Ojemann
authors.forename: Tae Sung
authors.initials: TS
authors.lastname: Park
authors.forename: Franz J
authors.initials: FJ
authors.lastname: Wippold
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007037:Hypothyroidism / Q000150:complications / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D010902:Pituitary Gland / Q000473:pathology*; D013974:Thyroxine / Q000627:therapeutic use*
chemical_list: D013974:Thyroxine