title: Periapical tissue responses and cementum regeneration with amalgam, SuperEBA, and MTA as root-end filling materials.
abstract: The purpose of this study was to compare the periapical tissue responses and cementum regeneration in response to three widely used root-end filling materials, amalgam, SuperEBA, and Mineral Trioxide Aggregate (MTA). These materials were placed using modern microsurgical techniques on endodontically treated dog premolars and molars. After 5 months, the cell and tissue reactions of surface-stained un-decalcified ground sections were evaluated by light microscopy and statistically analyzed. The major difference in the tissue responses to the three retrofilling materials were the degree of inflammation and types of inflammatory cells, number of fibrous capsule formations, cementum neoformation over these materials, osseous healing and resulting periodontal ligament thickness. MTA showed the most favorable periapical tissue response, with neoformation of cemental coverage over MTA. SuperEBA was superior to amalgam as a root-end filling material.
authors.affiliation: Department of Conservative Dentistry, College of Dentistry, Seoul National University, Korea.
authors.forename: Seung-Ho
authors.initials: SH
authors.lastname: Baek
authors.forename: Hanns
authors.initials: H
authors.lastname: Plenk
authors.forename: Syngcuk
authors.initials: S
authors.lastname: Kim
mesh_terms: D017607:Aluminum Compounds / Q000009:adverse effects / Q000494:pharmacology; D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects; D017610:Calcium Compounds / Q000009:adverse effects / Q000494:pharmacology; D016009:Chi-Square Distribution; D003723:Dental Amalgam / Q000009:adverse effects / Q000494:pharmacology; D003739:Dental Cementum / Q000187:drug effects* / Q000502:physiology; D017220:Dentin-Bonding Agents / Q000009:adverse effects / Q000494:pharmacology; D004285:Dogs; D004338:Drug Combinations; D005260:Female; D007249:Inflammation / Q000139:chemically induced; D008866:Microsurgery; D010087:Oxides / Q000009:adverse effects / Q000494:pharmacology; D010513:Periodontal Ligament / Q000187:drug effects / Q000502:physiology; D011897:Random Allocation; D012038:Regeneration / Q000187:drug effects*; D012184:Retrograde Obturation / Q000379:methods*; D012387:Root Canal Filling Materials / Q000009:adverse effects / Q000494:pharmacology*; D017640:Silicates / Q000009:adverse effects / Q000494:pharmacology
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D017220:Dentin-Bonding Agents; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate; D003723:Dental Amalgam; C084074:Super EBA