Clinical, virologic and immunologic profiles of a young infant with severe acute respiratory syndrome.
The clinical findings, plasma viral load, cytokines and chemokines of a 4-month-old infant with severe acute respiratory syndrome (SARS) were assessed at different phases of the disease. Ribavirin failed to inhibit SARS coronavirus (SARS-CoV) replication. One-step real time reverse transcription-polymerase chain reaction for plasma SARS-CoV RNA quantification was useful for early diagnosis and monitoring viremia.
Cheng
Frankie W T
FW
Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T.
Ng
Enders K O
EK
Li
Albert Martin
AM
Hon
Ellis K L
EK
Chiu
Rossa W K
RW
Lo
Y M Dennis
YM
Ng
Pak C
PC
D016207:Cytokines / Q000097:blood*; D005260:Female; D006801:Humans; D007223:Infant; D012367:RNA, Viral / Q000097:blood; D045473:Severe acute respiratory syndrome-related coronavirus / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology; D045169:Severe Acute Respiratory Syndrome / Q000276:immunology / Q000503:physiopathology / Q000821:virology; D013997:Time Factors; D019562:Viral Load
D016207:Cytokines; D012367:RNA, Viral