[Study of the novel tissue-specific RNA polymerase II transcription factor].
It has been established that retrogenes lose introns and regulatory regions. Most of them become pseudogenes, but some acquire tissue-specific functions. In this study, a contrary situation is described, when a retrogene from Drosophila melanogaster performs the main functions and is expressed in all tissues, while the initial gene is active only in a small part of the male germ cells. It is suggested that this phenomenon resulted from retroposition of the initial precursor gene in the transcription-suitable region of the genome.
Mardanov
P V
PV
Krasnov
A N
AN
Kurshakova
m M
mM
Nabirochkina
E N
EN
Georgieva
S G
SG
D000818:Animals; D029721:Drosophila Proteins / Q000235:genetics*; D004331:Drosophila melanogaster; D005786:Gene Expression Regulation; D016678:Genome; D008297:Male; D011544:Pseudogenes / Q000235:genetics; D012319:RNA Polymerase II / Q000235:genetics; D014157:Transcription Factors / Q000235:genetics*; D014158:Transcription, Genetic
D029721:Drosophila Proteins; D014157:Transcription Factors; C423782:e(y)2 protein, Drosophila; D012319:RNA Polymerase II