Quasienantiomers and quasiracemates: new tools for identification, analysis, separation, and synthesis of enantiomers.
The old adage "never mix pure organic compounds" holds in spades for enantiomers. After going to all the trouble to make enantiopure molecules, who in their right mind would ever mix them to make a racemate? Quasienantiomers are almost enantiomers, but not quite. Yet unlike enantiomers, the interest is not so much in separating them but in mixing them to make quasiracemates. This backwards thinking opens new possibilities for identification, analysis, separation and synthesis of enantiomers. A short history is provided, the terms are defined and illustrated, and recent applications of quasienantiomers, quasiracemates and related species are reviewed.
Zhang
Qisheng
Q
Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
Curran
Dennis P
DP
D002384:Catalysis; D006868:Hydrolysis; D013237:Stereoisomerism