title: Synthesis, spectral and electrochemical properties of Al(III) and Zn(II) complexes with flavonoids.
abstract: The synthesis, electrochemical and spectral (UV-vis, 1H NMR, IR, fluorescence) properties as well as thermal behaviors of Al(III) and Zn(II) complexes with the flavonoids quercetin (H2L(1)), rutin (H2L(2)) and galangin (HL(3)) are presented. The complexes may be formulated as [Al2(L(1))(H2O)8]Cl4, [Al3(L(2))2(H2O)12]Cl5, [Al(L(3))(H2O)4]Cl2, [Zn2(L(1))(H2O)4]Cl2, [Zn3(L(2))2(H2O)6]Cl2 and [Zn(L(3))(H2O)2]Cl. The higher fluorescence intensities of the complexes related to the free flavonoids, are attributed to the coordination of the ligands to the small, highly charged Al(III) and Zn(II) ions. The coordination effectively increases the rigidity of the ligand structure and increases the fluorescence quantum yield by reducing the probability of non-radiative energy dissipation process. Antioxidant activities of the compounds were also investigated under an electrochemical point of view. The cyclic voltammetric data show a considerable decrease of the oxidation potentials of the complexes related to that of the free flavonoids. Thus, the flavonoid-metal complexes are more effective antioxidants than the free flavonoids.
authors.affiliation: Departamento de Quimica, Faculdade de Filosofia Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Av. Bandeirantes 3900, Ribeirão Preto 14040-901, SP, Brazil.
authors.forename: Rubens F V
authors.initials: RF
authors.lastname: de Souza
authors.forename: Wagner F
authors.initials: WF
authors.lastname: De Giovani
mesh_terms: D000535:Aluminum / Q000737:chemistry*; D000975:Antioxidants / Q000737:chemistry; D004563:Electrochemistry; D005419:Flavonoids / Q000138:chemical synthesis / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D011794:Quercetin / Q000737:chemistry; D012431:Rutin / Q000737:chemistry; D013053:Spectrophotometry; D013696:Temperature; D015032:Zinc / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D008024:Ligands; C037032:galangin; D012431:Rutin; D011794:Quercetin; D000535:Aluminum; D015032:Zinc