Heart failure in the elderly: age-related differences in clinical profile and mortality.
BACKGROUND
Age influence in the prognosis in unselected patients with heart failure has not been widely studied.


OBJECTIVE
To evaluate possible differences in clinical profile and outcome of patients hospitalized with HF according to age.


RESULTS
During 1996, a total of 1065 hospital in-patients had confirmed heart failure, with follow-up data through 2002. Patients were separated in two groups < or = 75 and > 75 years of age. Older patients were less frequently men (32 vs. 52%) and had a higher prevalence of previous stroke (14 vs. 10%). Echocardiography was performed less frequently in older patients (55% vs. 78%) and normal systolic function (55 vs. 40%), and aortic stenosis (12 vs. 7%) were more prevalent. They received less anticoagulants (11 vs. 43%) and beta-blockers (2 vs. 7%), while the opposite happened with aspirin (32 vs. 23%) and diuretics (88 vs. 80%). During follow-up, 507 patients died: 55.9% vs. 38.5%. Being > 75 years of age was the strongest predictor of mortality HR: 1.7, CI 95% 1.5-2.1, P < 0.0001.


CONCLUSIONS
Patients with 76 or more years admitted with HF have a different clinical profile. Echocardiography, oral anticoagulation and beta-blockers were underused in these patients. Age was the strongest predictor of long-term mortality.
Martínez-Sellés
Manuel
M
Cardiology Department, Hospital Universitario Gregorio Marañón, Spain. mmselles@navegalia.com
García Robles
José A
JA
Prieto
Luis
L
Domínguez Muñoa
Marta
M
Frades
Elisa
E
D000367:Age Factors; D000368:Aged; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000503:physiopathology; D006801:Humans; D007297:Inpatients; D008297:Male; D009200:Myocardial Contraction / Q000502:physiology; D011237:Predictive Value of Tests; D015995:Prevalence; D011379:Prognosis; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate / Q000639:trends; D013997:Time Factors