title: Carbanion-mediated photocages: rapid and efficient photorelease with aqueous compatibility.
abstract: A new photocage is proposed, based on ketoprofen-derived compounds and mediated by carbanions. The new photocage has significant advantages over the widely used o-nitrobenzyl derivatives, including aqueous compatibility, faster photorelease, higher quantum yield, and innocuous byproducts. The photorelease of ibuprofen illustrates the properties of the new photocage.
authors.affiliation: Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario K1N 6N5, Canada.
authors.forename: Matthew
authors.initials: M
authors.lastname: Lukeman
authors.forename: Juan C
authors.initials: JC
authors.lastname: Scaiano
mesh_terms: D001577:Benzophenones / Q000737:chemistry*; D007660:Ketoprofen / Q000031:analogs & derivatives* / Q000737:chemistry; D010777:Photochemistry; D014867:Water / Q000737:chemistry
chemical_list: D001577:Benzophenones; D014867:Water; D007660:Ketoprofen