title: Primary angiosarcoma of the lung and pleura.
abstract: A 46 year old male smoker was admitted for severe continuing hemoptysis. Chest-X-rays and chest computed tomography revealed nodular infiltrates and bilateral hemothorax. Fiberoptic bronchoscopy resulted to non-diagnostic cytological and microbiological findings. Open lung and pleural biopsies after right thoracotomy revealed epithelioid angiosarcoma and further staging assessment showed secondary brain and liver foci. The patient received several courses of chemotherapy but he died one month later. The clinical, radiological, pathological, histochemical and therapeutic aspects of the disease are discussed. Angiosarcoma, a rare tumour with poor prognosis should be taken into consideration in the differential diagnosis of hemoptysis.
authors.affiliation: Department of Pneumonology, University Hospital of Ioannina, Greece.
authors.forename: G C
authors.initials: GC
authors.lastname: Maglaras
authors.forename: S
authors.initials: S
authors.lastname: Katsenos
authors.forename: J
authors.initials: J
authors.lastname: Kakadelis
authors.forename: C
authors.initials: C
authors.lastname: Katsanos
authors.forename: Z
authors.initials: Z
authors.lastname: Metafratzi
authors.forename: D G
authors.initials: DG
authors.lastname: Stefanou
authors.forename: M P
authors.initials: MP
authors.lastname: Vassiliou
authors.forename: S H
authors.initials: SH
authors.lastname: Constantopoulos
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001706:Biopsy; D001999:Bronchoscopy; D017809:Fatal Outcome; D006394:Hemangiosarcoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D010997:Pleural Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents