title: Family history of myopia is not related to the final amount of refractive error in low and moderate myopia.
abstract: BACKGROUND
  Previous research has found an association between family history and presence of myopia. It is possible that family history also could be related to the final amount of refractive error developed. If that were true, then family history of myopia could have predictive value for the amount of refractive error a child or young adult would develop after first lens prescription.
  
  
  METHODS
  Consecutive myopic adult outpatients were enrolled during the year 2003. They received a refractive examination and a questionnaire concerning age of onset of lens use, academic achievement, and parental history of myopia.
  
  
  RESULTS
  In the group of 271 mild and moderate myopes (myopia lower than -6 D) there were 157 subjects with at least one myopic parent and 114 subjects without family history. The presence or absence of a family history of myopia was not associated with either the final myopic refractive error (-3.2 +/- 1.5 D and -2.9 +/- 1.3 D, respectively, P = 0.08) or the age of onset of lens use (17.0 +/- 6.2 years vs 18.1 +/- 6.7 years, respectively, P = 0.15).
  
  
  CONCLUSIONS
  In the present retrospective study of a clinical sample of mild and moderate myopic subjects, family history of myopia did not show predictive value for either the age of first prescription, or the final refractive error developed in adulthood.
authors.affiliation: Department of Ophthalmology, San Luis Medical Centre, San Martin de Tours, Buenos Aires, Argentina. rafael@ar.inter.net
authors.forename: Rafael
authors.initials: R
authors.lastname: Iribarren
authors.forename: Alejandra
authors.initials: A
authors.lastname: Balsa
authors.forename: Alejandro
authors.initials: A
authors.lastname: Armesto
authors.forename: Pablo
authors.initials: P
authors.lastname: Chiaradia
authors.forename: Leopoldo
authors.initials: L
authors.lastname: Despontín
authors.forename: Andrea
authors.initials: A
authors.lastname: Fornaciari
authors.forename: Tomás
authors.initials: T
authors.lastname: Pfortner
mesh_terms: D000328:Adult; D017668:Age of Onset; D018450:Disease Progression; D004522:Educational Status; D005139:Eyeglasses; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000175:diagnosis* / Q000503:physiopathology* / Q000628:therapy; D012189:Retrospective Studies; D011795:Surveys and Questionnaires