title: [Multiple cerebral abscess caused by Nocardia brasilientis].
abstract: Streptococcus aureus, streptococci, and enterobacteria were major causative agents of abscesses of the brain. At present, associated infection is responsible for 60% of cerebral abscesses. When systemic and specific immunities are diminished, a risk for cerebral abscesses caused by fungi increases. Among them, there are the most common fungi Candida species or Aspergillus species. The paper gives an example of successful complex treatment of multiple cerebral abscesses caused by an association of Nocardia brasiliensis and Staphylococcus epidermidis. The specific feature of the observation was the correct diagnosis before intraoperative verification of cerebral abscesses. The disease developed in the presence of diminished systemic immunity and in the absence of specific immunity to Nocardia. Immunodeficiency could be caused by prior herpetic infection, Epstein-Barr disease, a wasp bite. The pathogen that was able to cause microstrokes played an indubitable role in the pathogenesis of the disease, which predisposed to the development of cerebral abscesses in patients with immunodeficiency. Impaired blood circulation in the occipital region could be also induced by wasp venom.
authors.forename: A N
authors.initials: AN
authors.lastname: Konovalov
authors.forename: R M
authors.initials: RM
authors.lastname: Khaitov
authors.forename: V N
authors.initials: VN
authors.lastname: Shimanskiĭ
authors.forename: I A
authors.initials: IA
authors.lastname: Aleksandrova
authors.forename: B V
authors.initials: BV
authors.lastname: Pinegin
authors.forename: S V
authors.initials: SV
authors.lastname: Serkov
authors.forename: N A
authors.initials: NA
authors.lastname: Murusidze
mesh_terms: D001922:Brain Abscess / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy*; D020806:Central Nervous System Bacterial Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D016867:Immunocompromised Host; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009617:Nocardia Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy*; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000276:immunology; D013212:Staphylococcus epidermidis