title: [Evaluation of emergency craniotomy for the treatment of patients with intracranial metastases of choriocarcinoma].
abstract: OBJECTIVE
  To study the diagnosis, management and prognosis of intracranial metastases of gestational trophoblastic tumour (GTT) patients who had emergency surgical decompression due to highly increased intracranial pressure.
  
  
  METHODS
  Ninety-three patients with intracranial metastases of gestational trophoblastic tumour were hospitalized in our department of Peking Union Medical College Hospital from 1985 to 2004. Thirteen of them who underwent emergency craniotomy were retrospectively analyzed, and all of them presented with raised intracranial pressure and intracerebral haemorrhagic mass.
  
  
  RESULTS
  Of the thirteen patients who underwent surgery in combination with multiagent systemic chemotherapy, seven achieved complete remission (CR), five had partial remission (PR), and one died of disease progression.
  
  
  CONCLUSIONS
  Emergency surgical treatment is the important method of choice for brain metastasis in patients displaying rapidly deteriorating signs. An undetermined intracranial haemorrhage in young female patients of reproductive age group should raise the suspicion of cerebral metastatic choriocarcinoma.
authors.affiliation: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
authors.forename: Juan-jun
authors.initials: JJ
authors.lastname: Yang
authors.forename: Yang
authors.initials: Y
authors.lastname: Xiang
authors.forename: Xiu-yu
authors.initials: XY
authors.lastname: Yang
authors.forename: Xi-run
authors.initials: XR
authors.lastname: Wan
authors.forename: Ren-zhi
authors.initials: RZ
authors.lastname: Wang
authors.forename: Zu-yuan
authors.initials: ZY
authors.lastname: Ren
authors.forename: Hong-mei
authors.initials: HM
authors.lastname: Yin
authors.forename: Wei-dong
authors.initials: WD
authors.lastname: Guo
authors.forename: Xiao-mu
authors.initials: XM
authors.lastname: Ou
mesh_terms: D000328:Adult; D002822:Choriocarcinoma / Q000473:pathology / Q000601:surgery*; D003399:Craniotomy; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D012189:Retrospective Studies; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery*; D055815:Young Adult