title: Is there any difference in anesthetic management of biliary atresia and glycogen storage disease patients undergoing liver transplantation?
abstract: BACKGROUND
  The purpose of the study was to compare the intraoperative blood glucose changes and the dosage of glucose infused between biliary atresia and glycogen storage disease (GSD) patients undergoing living donor liver transplantation (LDLT).
  
  
  METHODS
  The anesthesia records of biliary atresia and GSD patients undergoing LDLT were reviewed retrospectively. The levels of intraoperative blood glucose before operation, after induction of anesthesia, in the dissection, anhepatic, 10 min after reperfusion, and at the end of operation, as well as the dosage glucose infused, were compared between groups. The Mann-Whitney U test was used for statistical analysis; P < 0.05 was regarded as significant.
  
  
  RESULTS
  Seventy-two biliary atresia patients were grouped into group I (GI) and 8 GSD patients into group II (GII). The blood glucose levels of both groups increased after operation and remained hyperglycemic, around 100-300 mg/dl, until the end of the operation. The mean glucose amounts infused were 2.7 +/- 1.9 and 2.5 +/- 1.15 mg/kg/min for GI and GII, respectively.
  
  
  CONCLUSIONS
  No significant difference was found in the anesthetic management between groups. The only difference was that the GSD patients required continuous glucose supply the night before the operation, while biliary atresia patients did not.
authors.affiliation: Department of Anesthesiology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University, Taipei, Taiwan, Republic of China.
authors.forename: Bruno
authors.initials: B
authors.lastname: Jawan
authors.forename: Chia-Chih
authors.initials: CC
authors.lastname: Tseng
authors.forename: Yaw-Sen
authors.initials: YS
authors.lastname: Chen
authors.forename: Chih-Chi
authors.initials: CC
authors.lastname: Wang
authors.forename: Yu-Fan
authors.initials: YF
authors.lastname: Cheng
authors.forename: Tung-Liang
authors.initials: TL
authors.lastname: Huang
authors.forename: Hock-Liew
authors.initials: HL
authors.lastname: Eng
authors.forename: King-Wah
authors.initials: KW
authors.lastname: Chiu
authors.forename: Shir-Hor
authors.initials: SH
authors.lastname: Wang
authors.forename: Chih-Che
authors.initials: CC
authors.lastname: Lin
authors.forename: Tsan-Shiun
authors.initials: TS
authors.lastname: Lin
authors.forename: Yueh-Wei
authors.initials: YW
authors.lastname: Liu
authors.forename: Chao-Long
authors.initials: CL
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000758:Anesthesia / Q000379:methods*; D001656:Biliary Atresia / Q000097:blood / Q000601:surgery*; D001786:Blood Glucose / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D005440:Fluid Therapy; D006008:Glycogen Storage Disease / Q000097:blood / Q000601:surgery*; D006801:Humans; D007223:Infant; D016031:Liver Transplantation; D016343:Monitoring, Intraoperative; D012189:Retrospective Studies
chemical_list: D001786:Blood Glucose