title: FR207944, an antifungal antibiotic from Chaetomium sp. No. 217 II. Isolation and structure elucidation.
abstract: We discovered FR207944 produced by Chaetomium sp. No. 217 in the course of screening for antifungal antibiotics from natural products. FR207944 is identical with fuscoatroside, described in the preceding paper as an anti-Aspergillus flavus agent. Determination of the relative stereochemistry of fuscoatroside was made formally by comparison with WF11605 (16-Oxo-FR207944). We confirmed the stereochemistry on the basis of single crystal X-ray analysis.
authors.affiliation: Fermentation Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Tokyo, Japan. motoo_kobayashi@po.fujisawa.co.jp
authors.forename: Motoo
authors.initials: M
authors.lastname: Kobayashi
authors.forename: Seiji
authors.initials: S
authors.lastname: Yoshimura
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Kinoshita
authors.forename: Michizane
authors.initials: M
authors.lastname: Hashimoto
authors.forename: Seiji
authors.initials: S
authors.lastname: Hashimoto
authors.forename: Shigehiro
authors.initials: S
authors.lastname: Takase
authors.forename: Akihiko
authors.initials: A
authors.lastname: Fujie
authors.forename: Motohiro
authors.initials: M
authors.lastname: Hino
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Hori
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification*; D002597:Chaetomium / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification*; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification*
chemical_list: D000935:Antifungal Agents; C503272:FR207944; D006027:Glycosides; D014315:Triterpenes