title: [Chronic recurrent multifocal osteomyelitis: report of five cases].
abstract: Chronic recurrent multifocal osteomyelitis is a rare disease of unknown etiology that mainly affects children. We present a retrospective review of the medical records of five patients with a diagnosis of chronic recurrent multifocal osteomyelitis in an infectious diseases clinic at a tertiary center. We describe the epidemiological, clinical and radiological features, laboratory, microbiological and histological findings, treatment, course and prognosis in these patients. There is no specific treatment for chronic recurrent multifocal osteomyelitis. There are new treatment options such the combination of azithromycin and calcitonin in children without clinical improvement with non-steroidal anti-inflammatory drugs.
authors.affiliation: Unidad de Niños Pequeños e Inmunodeficiencias, Departamento de Pediatría, Hospital 12 de Octubre, Madrid, España. saraguillen@wanadoo.es
authors.forename: S
authors.initials: S
authors.lastname: Guillén Martín
authors.forename: S
authors.initials: S
authors.lastname: Belda Hofheinz
authors.forename: P
authors.initials: P
authors.lastname: Rojo Conejo
authors.forename: B
authors.initials: B
authors.lastname: Losada Pinedo
authors.forename: J T
authors.initials: JT
authors.lastname: Ramos Amador
authors.forename: J
authors.initials: J
authors.lastname: Clemente Pollan
authors.forename: J
authors.initials: J
authors.lastname: Ruiz Contreras
mesh_terms: D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010019:Osteomyelitis / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology / Q000628:therapy; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies