title: Indole alkaloids from the leaves of Philippine Alstonia scholaris.
abstract: The first seco-uleine alkaloids, manilamine (1) (18-hydroxy-19,20-dehydro-7,21-seco-uleine) and N4-methyl angustilobine B (2), were isolated from the (pH 5) alkaloid extract of Philippine Alstonia scholaris leaves together with the known indole alkaloids 19,20-(E)-vallesamine (3), angustilobine B N4-oxide (4), 20(S)-tubotaiwine (5), and 6,7-seco-angustilobine B (6). The structure of the alkaloids was established from MS and NMR experiments.
authors.affiliation: Phytochemistry Laboratory, Research Center for the Natural Sciences, Thomas Aquinas Research Complex, University of Santo Tomas, Espana St., Manila 1008, Philippines.
authors.forename: Allan Patrick G
authors.initials: AP
authors.lastname: Macabeo
authors.forename: Karsten
authors.initials: K
authors.lastname: Krohn
authors.forename: Dietmar
authors.initials: D
authors.lastname: Gehle
authors.forename: Roger W
authors.initials: RW
authors.lastname: Read
authors.forename: Joseph J
authors.initials: JJ
authors.lastname: Brophy
authors.forename: Geoffrey A
authors.initials: GA
authors.lastname: Cordell
authors.forename: Scott G
authors.initials: SG
authors.lastname: Franzblau
authors.forename: Alicia M
authors.initials: AM
authors.lastname: Aguinaldo
mesh_terms: D031051:Alstonia / Q000737:chemistry*; D026121:Indole Alkaloids / Q000737:chemistry*; D008956:Models, Chemical; D015394:Molecular Structure; D010679:Philippines; D018515:Plant Leaves / Q000737:chemistry*
chemical_list: D026121:Indole Alkaloids