Immunology: how do T cells recognize antigen?
T cells recognize small fragments of microorganisms (antigens) on the surface of other cells using T cell antigen receptors. The mechanism by which these receptors signal into T cells is controversial, but two recent studies provide important new clues.
Choudhuri
Kaushik
K
Sir William Dunn School of Pathology, University of Oxford, UK.
Kearney
Alice
A
Bakker
Talitha R
TR
van der Merwe
P Anton
PA
D000941:Antigens / Q000276:immunology* / Q000378:metabolism; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology*; D008285:Major Histocompatibility Complex / Q000276:immunology; D018448:Models, Immunological; D011948:Receptors, Antigen, T-Cell / Q000378:metabolism*; D015398:Signal Transduction / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D000941:Antigens; D011948:Receptors, Antigen, T-Cell