title: [Biotransformation of mexidol in inbred BALB/C and C57BL/6 mice].
abstract: The pharmacokinetics and biotransformation of mexidol was studied in BALB/C and C57BL/6 mice. The blood plasma contains dealkylated metabolites, and the urine contains glucuronoconjugated derivatives of the drug. The process of glucuronoconjugation more intensively proceeds in C57BL/6 mice than in BALB/C mice.
authors.forename: S B
authors.initials: SB
authors.lastname: Seredenin
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Kravtsova
authors.forename: A K
authors.initials: AK
authors.lastname: Sarieva
authors.forename: V P
authors.initials: VP
authors.lastname: Zherdev
authors.forename: G B
authors.initials: GB
authors.lastname: Kolyvanova
authors.forename: T A
authors.initials: TA
authors.lastname: Voronina
mesh_terms: D000818:Animals; D001711:Biotransformation; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010847:Picolines / Q000493:pharmacokinetics*; D011619:Psychotropic Drugs / Q000493:pharmacokinetics*; D013045:Species Specificity; D014018:Tissue Distribution
chemical_list: D010847:Picolines; D011619:Psychotropic Drugs; C070020:emoxypine succinate