title: [Markedly increased red cell fragmentations counted as platelets in a patient with thrombotic microangiopathy].
abstract: A patient with acute lymphocytic leukemia (ALL) experienced severe thrombotic microangiopathy (TMA) after allo-bone marrow transplantation (BMT). She had high risk for TMA; due to total body irradiation (TBI), intensive chemotherapy, treatment with Ciclosporin and association with veno-occlusive disease (VOD). Markedly increased fragmentations of red blood cells were observed in this case, and were incorrectly counted as platelets by a fully automated blood cells counter. Careful evaluation of the platelet count is necessary in patients with red cell fragmentations.
authors.affiliation: Department of Laboratory Medicine, Mie University School of Medicine, Tsu 514-8507.
authors.forename: Hideo
authors.initials: H
authors.lastname: Wada
authors.forename: Miho
authors.initials: M
authors.lastname: Sakakura
authors.forename: Atsusi
authors.initials: A
authors.lastname: Fujieda
authors.forename: Akane
authors.initials: A
authors.lastname: Sakaguchi
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Abe
mesh_terms: D000328:Adult; D004912:Erythrocytes / Q000473:pathology*; D005260:Female; D006801:Humans; D010976:Platelet Count / Q000592:standards*; D011697:Purpura, Thrombotic Thrombocytopenic / Q000097:blood*