title: (-)-Hydroxycitrate ingestion and endurance exercise performance.
abstract: We have been interested in the ergogenic aid effects of food components and supplements for enhancing endurance exercise performance. For this purpose, acute or chronic (-)-hydroxycitrate (HCA) ingestion might be effective because it promotes utilization of fatty acid as an energy source. HCA is a competitive inhibitor of the enzyme ATP: citrate lyase, thereby increasing inhibition of lipogenesis in the body. Many researchers have reported that less body fat accumulation and sustained satiety cause less food intake. After focusing on exercise performance with HCA ingestion, we came up with different results that show positive effects or not. However, our previously reported data showed increased use of fatty acids during moderate intensity exercise. For future research, HCA and co-ingestion of other supplements, such as carnitine or caffeine, might have greater effect on glycogen-sparing than HCA alone.
authors.affiliation: Department of Physical Education, Konkuk University, Seoul 143-701, Korea. kwlim21@hotmail.com
authors.forename: Kiwon
authors.initials: K
authors.lastname: Lim
authors.forename: Sungpil
authors.initials: S
authors.lastname: Ryu
authors.forename: Heajung
authors.initials: H
authors.lastname: Suh
authors.forename: Kengo
authors.initials: K
authors.lastname: Ishihara
authors.forename: Tohru
authors.initials: T
authors.lastname: Fushiki
mesh_terms: D001275:ATP Citrate (pro-S)-Lyase / Q000037:antagonists & inhibitors; D000818:Animals; D002951:Citrates / Q000008:administration & dosage* / Q000494:pharmacology / Q000502:physiology; D004040:Dietary Carbohydrates / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000494:pharmacology; D015444:Exercise / Q000502:physiology; D005227:Fatty Acids / Q000378:metabolism; D005638:Fruit / Q000737:chemistry; D029760:Garcinia / Q000737:chemistry; D006801:Humans; D008055:Lipids / Q000096:biosynthesis; D010807:Physical Endurance / Q000187:drug effects*
chemical_list: D002951:Citrates; D004040:Dietary Carbohydrates; D004791:Enzyme Inhibitors; D005227:Fatty Acids; D008055:Lipids; C007999:hydroxycitric acid; D001275:ATP Citrate (pro-S)-Lyase