Granulosa cell tumour: a recurrence 40 years after initial diagnosis.
BACKGROUND
Granulosa cell tumours are rare ovarian malignancies accounting for 2% to 5% of ovarian tumours. They are characterized by late recurrences, with the latest recurrence reported 37 years after first diagnosis.


METHODS
A 73-year-old woman who had surgery for a granulosa cell tumour in her early 30s and who presented with a recurrence 40 years later.


CONCLUSIONS
Patients and their physicians should be made aware that there is a potential for a granulosa cell tumour to recur many years in the future.
East
Nathalie
N
Department of Gynecology Oncology, CHUM, Notre-Dame Hospital, Montreal QC.
Alobaid
Abdulaziz
A
Goffin
Frédéric
F
Ouallouche
Karim
K
Gauthier
Philippe
P
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D005500:Follow-Up Studies; D006106:Granulosa Cell Tumor / Q000473:pathology*; D006801:Humans; D007265:Inhibins / Q000032:analysis; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*; D011980:Receptors, Progesterone / Q000032:analysis; D014746:Vimentin / Q000032:analysis
D014408:Biomarkers, Tumor; D011980:Receptors, Progesterone; D014746:Vimentin; C094377:inhibin-alpha subunit; D007265:Inhibins