Hypertrophic cardiomyopathy and arrhythmogenic right ventricular dysplasia in young patients.
The annual incidence of sudden cardiac death in young athletes is approximately 1 in 200,000. The most common causes include hypertrophic cardiomyopathy and arrhythmogenic right ventricular dysplasia/cardiomyopathy. These genetic disorders typically manifest in the second decade of life and have the potential for sudden death as the first symptom. Medical care providers must be aware of these disease entities when evaluating patients with seizures, syncope, and/or palpitations. The purpose of this article is to describe their genetics, clinical presentation, and diagnosis.
Frias
Patricio A
PA
Sibley Heart Center Cardiology, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA 30329, USA. friasp@kidsheart.com
D019571:Arrhythmogenic Right Ventricular Dysplasia / Q000150:complications* / Q000235:genetics / Q000473:pathology; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications* / Q000235:genetics / Q000473:pathology; D016757:Death, Sudden, Cardiac / Q000453:epidemiology* / Q000209:etiology* / Q000473:pathology; D006801:Humans