[The research progression of S100beta as a neurochemistry maker].
S100beta is one kind of the calcium binding proteins. As growth factor of neuraxon, it is excreted by neuroglial cell, and distributing in nerve tissue extensively. Although S100beta has very important values neurophysiological, it also has neurotoxicity with excreting overmuch. Concentration of S100beta changes regularity in serum after the brain injury. In addition, it has a close relations with the degree of brain damage, which can be regarded as the neural new marker of biochemistry after brain damage. The advances of S100beta protein, in the research on neurophysiological values and its application for nerve tissue injury, disease were reviewed.
Huang
Ping
P
Department of Forensic Medicine, Medical college, Xi'an Jiaotong University, Xi'an 710061, China.
Wang
Zhen-yuan
ZY
Tuo
Ya
Y
D000544:Alzheimer Disease / Q000378:metabolism / Q000473:pathology; D015415:Biomarkers / Q000097:blood; D001930:Brain Injuries / Q000097:blood* / Q000473:pathology / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000097:blood / Q000473:pathology; D006801:Humans; D009414:Nerve Growth Factors / Q000097:blood*; D009457:Neuroglia / Q000378:metabolism*; D011180:Postmortem Changes; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins / Q000097:blood*; D012720:Severity of Illness Index; D013997:Time Factors
D015415:Biomarkers; D009414:Nerve Growth Factors; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins