[New approaches to diagnosis of left ventricular hypertrophy by dipolar electrocardiography].
OBJECTIVE
To show possibilities of dipolar electrocardiography (DECG) in diagnosis of left ventricular hypertrophy (LVH).


METHODS
We made DECG in 151 healthy subjects and 158 hypertensive patients. To characterize DECG quantitatively, we used the integral activation duration index (IADI) calculated as a weighted sum of the areas with different duration of activation, module of the maximal vector QRS, QRSxIADI (IADIM).


RESULTS
In patients with left ventricular myocardial mass index (LVMMI) under 150 g/m2, sensitivity of DECG was 38-49%, in the index over 150 g/m2 sensitivity reached 38-75%, specificity 89-98% compared to healthy examinees and 72-82% compared to hypertensive patients without LVH. The IADIM parameter correlates directly (moderate correlation) with duration of QRS complex and LVMMI.


CONCLUSIONS
Possibilities of using parameters IADI and IADIM for assessment of electrophysiological myocardial remodeling and their correlation with other methods need further investigations.
Blinova
E V
EV
Sakhnova
T A
TA
Sergakova
L M
LM
Ataullakhanova
D M
DM
Oshchepkova
E V
EV
Lazareva
N V
NV
Aĭdu
E A
EA
Trunov
V G
VG
Titomir
L I
LI
D000328:Adult; D004562:Electrocardiography / Q000295:instrumentation*; D004867:Equipment Design; D005260:Female; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity