title: Retinal nerve fiber layer thickness is unaffected in migraine patients.
abstract: OBJECTIVE
  To search for possible structural effects of migraine on the retina.
  
  
  METHODS
  The study group included 39 consecutive migraine patients, 15 with visual aura and 24 without aura, and 25 healthy subjects as the control group. Scanning laser polarimetry was used to measure and compare retinal nerve fiber layer (RNFL) thickness between migraine and control groups.
  
  
  RESULTS
  The mean age of the patients and the control group were 35.64 +/- 8.3 and 35.96 +/- 9.14 years, respectively (P = 0.92) and the mean duration of migraine in patients with aura and without aura as 4.4 +/- 2.9 and 5.3 +/- 4.3 years, respectively (P = 0.68). Parameters related to RNFL thickness were found to be similar (P > 0.001) in migraine and control subjects. After examining the whole patient group migraine patients with and without aura were compared to each other and the control group individually for RNFL thickness parameters. Briefly no statistical difference was found for any of the test parameters between migraine patients with aura, without aura and controls (P > 0.001).
  
  
  CONCLUSIONS
  Retinal nerve fiber layer thickness was found to be unaffected in migraine patients.
authors.affiliation: Department of Neurology, Faculty of Medicine, Kirikkale University, Kirikkale, Turkey. fundauysaltan@yahoo.com
authors.forename: F U
authors.initials: FU
authors.lastname: Tan
authors.forename: C
authors.initials: C
authors.lastname: Akarsu
authors.forename: R
authors.initials: R
authors.lastname: Güllü
mesh_terms: D000293:Adolescent; D000328:Adult; D001369:Axons / Q000473:pathology*; D005260:Female; D006801:Humans; D047569:Laser Scanning Cytometry; D008297:Male; D008875:Middle Aged; D020325:Migraine with Aura / Q000150:complications* / Q000503:physiopathology; D009412:Nerve Fibers / Q000473:pathology*; D009898:Optic Disk / Q000473:pathology; D012016:Reference Values; D012160:Retina / Q000473:pathology*; D012164:Retinal Diseases / Q000175:diagnosis / Q000209:etiology*; D012165:Retinal Ganglion Cells / Q000473:pathology