title: [Study on inhibition on alpha-glucosidase and analysis of the hypoglycemic composition of lobster sauce].
abstract: OBJECTIVE
  To study the effects of lobster sauce and polysaccharide extracts on alpha-1,4-glucosidase activity by establishing on enzyme-inhibitor model.
  
  
  METHODS
  Glucosidase activity was assayed at PH optima by PNPG substrate. Lobster sauce extracts were prepared by soaking, centrifagation. Polysaccharide were prepared by soaking, centrifagation, separation.
  
  
  RESULTS
  Lobster sauce and polysaccharide can inhibit alpha-1,4-glucosidase.
  
  
  CONCLUSIONS
  This finding suggested that their hypoglycemic mechanism was similar to Acarbose. Lobster sauce may contain phenyalanine.
authors.affiliation: North China Coal Medical College, Tangshan 063000.
authors.forename: Ruihua
authors.initials: R
authors.lastname: Guo
authors.forename: Li
authors.initials: L
authors.lastname: Zhai
authors.forename: Zhengmeng
authors.initials: Z
authors.lastname: Liu
authors.forename: Heping
authors.initials: H
authors.lastname: Wang
authors.forename: Yunsen
authors.initials: Y
authors.lastname: Zhao
authors.forename: Yanmei
authors.initials: Y
authors.lastname: Sun
authors.forename: Hongbo
authors.initials: H
authors.lastname: Zou
mesh_terms: D001786:Blood Glucose / Q000378:metabolism; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D004789:Enzyme Activation; D065089:Glycoside Hydrolase Inhibitors; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry; D011134:Polysaccharides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D013025:Glycine max / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D001786:Blood Glucose; D004365:Drugs, Chinese Herbal; D065089:Glycoside Hydrolase Inhibitors; D007004:Hypoglycemic Agents; D011134:Polysaccharides; D014867:Water