title: Compassionate use of quinacrine in Creutzfeldt-Jakob disease fails to show significant effects.
authors.forename: Julián
authors.initials: J
authors.lastname: Benito-León
mesh_terms: D000328:Adult; D001921:Brain / Q000187:drug effects / Q000503:physiopathology; D002746:Chlorpromazine / Q000627:therapeutic use*; D007562:Creutzfeldt-Jakob Syndrome / Q000188:drug therapy* / Q000503:physiopathology; D004252:DNA Mutational Analysis; D018492:Dopamine Antagonists / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D005260:Female; D006801:Humans; D034062:Insomnia, Fatal Familial / Q000188:drug therapy* / Q000235:genetics / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009154:Mutation / Q000235:genetics; D011796:Quinacrine / Q000627:therapeutic use*; D017211:Treatment Failure
chemical_list: D018492:Dopamine Antagonists; D004791:Enzyme Inhibitors; D011796:Quinacrine; D002746:Chlorpromazine