Synthetic strategies to chiral organosulfur donors related to bis(ethylenedithio)tetrathiafulvalene.
Syntheses of enantiopure organosulfur donors by three different strategies requiring only four-six steps are reported. The key step involves either double substitution of an enantiopure cyclic sulfate ester by a dithiolate, attachment of a chiral diol as a ketal, or completely diastereoselective cycloaddition of 1,3-dithiole-2,4,5-trithione to an enantiopure alkene.
Griffiths
Jon-Paul
JP
School of Biomedical and Natural Sciences, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UK.
Nie
Hui
H
Brown
R James
RJ
Day
Peter
P
Wallis
John D
JD
D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D021241:Spectrometry, Mass, Electrospray Ionization; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013457:Sulfur Compounds / Q000138:chemical synthesis* / Q000737:chemistry
C472948:BEDT-TTF; D013438:Sulfhydryl Compounds; D013457:Sulfur Compounds