Conventional synapses for unconventional cells.
Powerful synapses between climbing fibers (CF) and Purkinje cells are crucial to cerebellar motor learning. In this issue of Neuron, Lin and colleagues provide compelling evidence for the existence of direct synaptic contacts between CFs and NG2-expressing glia cells, adding to the intrigue of neuro-glial interactions.
Beierlein
Michael
M
Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA.
Regehr
Wade G
WG
D000818:Animals; D006801:Humans; D011689:Purkinje Cells / Q000166:cytology / Q000502:physiology*; D013569:Synapses / Q000502:physiology*