title: Prefrontal brain magnetic activity: effects of memory task demands.
abstract: Changes in spatiotemporal profiles of brain magnetic activity were investigated in healthy volunteers as a function of varying demands for phonological storage of spoken pseudowords. Greater activity for the phonological memory task was restricted to the dorsolateral prefrontal cortex (DLPFC) in the left hemisphere. During performance of the memory task, activity was initially found in the left superior temporal gyrus (between 100 and 200 ms), followed by activity in the ventrolateral prefrontal, motor, and premotor cortices (between 200 and 300 ms). Activity in DLPFCs was first observed consistently across participants later, between 300 and 400 ms. The data are consistent with the purported role of posterior temporal cortices in phonological analysis and in the online storage of phonological information, the contribution of ventrolateral and motor processing areas in establishment and short-term maintenance of articulatory representations through rehearsal, and the role of DLPFCs in the executive control of the maintenance operation.
authors.affiliation: Centro de Magnetoencefalografia Dr Pérez Modrego, Universidad Complutense Madrid.
authors.forename: Fernando
authors.identifier: 0000-0002-3195-0071
authors.initials: F
authors.lastname: Maestú
authors.affiliation: Centro de Magnetoencefalografia Dr Pérez Modrego, Universidad Complutense Madrid.
authors.forename: Pablo
authors.identifier: 0000-0003-4539-6857
authors.initials: P
authors.lastname: Campo
authors.affiliation: Centro de Magnetoencefalografia Dr Pérez Modrego, Universidad Complutense Madrid.
authors.forename: Almudena
authors.identifier: 0000-0002-4181-4284
authors.initials: A
authors.lastname: Capilla
authors.affiliation: Department of Neurosurgery, Vivian L. Smith Center for Neurologic Research, University of Texas-Houston Medical School.
authors.forename: Panagiotis G
authors.identifier: 0000-0002-0116-8564
authors.initials: PG
authors.lastname: Simos
authors.affiliation: Unidad de Daño Cerebral, Hospital Beata María Ana de Jesús.
authors.forename: Nuria
authors.initials: N
authors.lastname: Paúl
authors.affiliation: Departamento de Psicologia, Universidad Camilo José Cela.
authors.forename: Santiago
authors.initials: S
authors.lastname: Fernandez
authors.affiliation: Centro de Magnetoencefalografia Dr Pérez Modrego, Universidad Complutense Madrid.
authors.forename: Alberto
authors.identifier: 0000-0001-9998-8343
authors.initials: A
authors.lastname: Fernández
authors.affiliation: Centro de Magnetoencefalografia Dr Pérez Modrego, Universidad Complutense Madrid.
authors.forename: Carlos
authors.initials: C
authors.lastname: Amo
authors.affiliation: Departamento Psicología Básica II, Universidad Complutense Madrid.
authors.forename: Javier
authors.initials: J
authors.lastname: González-Marqués
authors.affiliation: Centro de Magnetoencefalografia Dr Pérez Modrego, Universidad Complutense Madrid.
authors.forename: Tomás
authors.initials: T
authors.lastname: Ortiz
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods; D000328:Adult; D000704:Analysis of Variance; D001931:Brain Mapping; D004558:Electric Stimulation; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008280:Magnetics; D015225:Magnetoencephalography / Q000379:methods; D008297:Male; D008568:Memory / Q000502:physiology*; D009483:Neuropsychological Tests; D010700:Phonetics; D017397:Prefrontal Cortex / Q000502:physiology*; D017603:Signal Detection, Psychological / Q000502:physiology; D013997:Time Factors; D014706:Verbal Learning / Q000502:physiology*