title: The gem-dialkyl effect in electron transfer reactions: rapid synthesis of seven-membered rings through an electrochemical annulation.
abstract: An electrochemical furan annulation strategy has been developed for the synthesis of seven-membered rings. Key to the success of the annulation is the placement of a gem-dialkyl group in the tether. Voltammetric studies indicate that this effect lowers the oxidation potential by approximately 110 mV.
authors.affiliation: Department of Chemistry, Dartmouth College, Hanover, New Hampshire 03755, USA.
authors.forename: Jeffrey B
authors.initials: JB
authors.lastname: Sperry
authors.forename: Dennis L
authors.initials: DL
authors.lastname: Wright
mesh_terms: D003500:Cyclization; D003508:Cycloheptanes / Q000138:chemical synthesis* / Q000737:chemistry; D004224:Diterpenes / Q000138:chemical synthesis*; D004563:Electrochemistry; D005663:Furans / Q000737:chemistry*
chemical_list: D003508:Cycloheptanes; D004224:Diterpenes; D005663:Furans; C482765:tricholomalide A