title: Increased glycocalicin index and normal thrombopoietin levels in patients with idiopathic thrombocytopenic purpura with a decreased rate of platelet production.
abstract: Platelet kinetic studies in idiopathic thrombocytopenic purpura (ITP) have shown that in a subgroup of patients a shortened mean platelet life (MPL) is associated with a decreased platelet production rate (PPR). Other methods of studying certain aspects of thrombocytopoiesis are the plasma concentrations of thrombopoietin and glycocalicin.
authors.forename: Ewout J
authors.initials: EJ
authors.lastname: Houwerzijl
authors.forename: Henk
authors.initials: H
authors.lastname: Louwes
authors.forename: Mariet T
authors.initials: MT
authors.lastname: Esselink
authors.forename: Jan W
authors.initials: JW
authors.lastname: Smit
authors.forename: Edo
authors.initials: E
authors.lastname: Vellenga
authors.forename: Joost Th M
authors.initials: JT
authors.lastname: de Wolf
mesh_terms: D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000473:pathology; D001853:Bone Marrow / Q000473:pathology; D002470:Cell Survival; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019038:Platelet Glycoprotein GPIb-IX Complex / Q000032:analysis*; D011696:Purpura, Thrombocytopenic / Q000097:blood*; D034061:Thrombopoiesis; D013926:Thrombopoietin / Q000097:blood*
chemical_list: D019038:Platelet Glycoprotein GPIb-IX Complex; C023592:glycocalicin; D013926:Thrombopoietin