title: [Expression of the lipopolysaccharide receptors in the rat liver cells in inflammation and in norm].
abstract: The liver can be a primary target organ for bacterial endotoxins--lipopolysaccharides, which serve as the major triggers of anaphylotoxin's generation. Both lipopolysaccharides and anaphylotoxins induce the acute-phase reaction in the liver. The acute-phase reaction comprises a variety of systemic changes. Synthesis of several plasma proteins in the liver and glucose output from hepatocytes undergo dramatic changes during inflammation. These changes are mediated by soluble factors. Mechanism of signal transduction is reviewed in detail. Attention is payed to the differences between expression of the lipopolysaccharide receptors under normal and inflammatory conditions.
authors.forename: N V
authors.initials: NV
authors.lastname: Byts'
authors.forename: S V
authors.initials: SV
authors.lastname: Khyzhniak
mesh_terms: D000818:Animals; D006505:Hepatitis / Q000378:metabolism*; D018836:Inflammation Mediators / Q000378:metabolism*; D018950:Lipopolysaccharide Receptors / Q000096:biosynthesis*; D008099:Liver / Q000166:cytology / Q000378:metabolism*; D051381:Rats
chemical_list: D018836:Inflammation Mediators; D018950:Lipopolysaccharide Receptors