title: Determinants of subjective quality of life in depressed patients: the role of self-esteem, response styles, and social support.
abstract: BACKGROUND
  We aimed to assess the subjective quality of life (QOL) in depressed patients after discharge from inpatient treatment and to investigate the net impact of self-related constructs (self-esteem, response styles to depressed mood) and of social support on specific subjective QOL domains.
  
  
  METHODS
  Four weeks after discharge from inpatient treatment, 89 unipolar depressed patients were assessed with a comprehensive battery of psychopathology and psychosocial measures. Subjective QOL was assessed using the World Health Organization Quality of Life Scale (WHOQOL-BREF). Analyses included hierarchical regressions.
  
  
  RESULTS
  Non-remitted patients reported poorer subjective QOL than fully and partially remitted patients regarding physical and psychological health, and overall QOL. After adjusting for demographic and clinical history variables, interviewer-rated severity of depression accounted for 4% to 36% of the variance in individual QOL domain scores. Self-esteem, rumination, distraction and the existence of a partnership added further increments to the explained variance of the psychological QOL domain. Rumination, partnership, and network size of family members providing psychological crisis support also predicted subjective QOL on the social relations domain.
  
  
  CONCLUSIONS
  Our results suggest that self-esteem, response styles to depressed mood, and social support characteristics contribute substantially to the psychological and social domains of subjective QOL in depressed patients. These associations are not attributable to concurrent symptom severity. Therapy with depressed patients should not only focus on symptom reduction but should help the patients to establish and maintain supportive relationships and to enhance self-appreciation and skills to cope with negative mood in order to improve psychological well-being and health-related quality of life.
authors.affiliation: Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, P.O. Box 122120, 68072 Mannheim, Germany. kuehner@zi-mannheim.de
authors.forename: Christine
authors.initials: C
authors.lastname: Kuehner
authors.forename: Christin
authors.initials: C
authors.lastname: Buerger
mesh_terms: D002648:Child; D003866:Depressive Disorder / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D010551:Personality; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology*; D012649:Self Concept; D012944:Social Support; D011795:Surveys and Questionnaires