title: Effect of a hydroxyl ion-releasing composite resin on plaque acidogenicity.
abstract: The aim of this in vivo study was to evaluate the neutralizing capacity, registered as change of plaque acidogenicity, on aged proximal restorations of an ion-releasing composite resin (IRCR), which releases hydroxyl, calcium, and fluoride ions at low pH. Twenty patients, with a mean age of 63 years (range 43-85), participated. All had one aged proximal IRCR restoration (mean age 15 months) and one nonrestored enamel surface to make an intraindividual comparison possible. The neutralizing effect of the IRCR was evaluated by measuring plaque pH, using the microtouch method, after a mouthrinse with 10% sucrose. The plaque pH measurements were repeated 1.5 years later on the IRCR (mean age 34 months), the enamel surfaces and a universal hybrid composite resin (CR). At both 15 and 34 months, the plaque on the IRCR surfaces showed the least acidogenic potential for the whole 60-min time interval. The largest differences between the IRCR, CR and enamel were found during the first 15 min. At 15 months, the total areas under the plaque pH curve (AUC(5.7) and AUC(6.2)) differed significantly between the IRCR and enamel surfaces for the time periods 0-5 min and 5-15 min. At 34 months, significant differences were found between IRCR and CR at the 0- to 5-min time period. It can be concluded that IRCR restorations countered the plaque pH fall and maintained it at levels where less enamel and dentin demineralization can occur.
authors.affiliation: Dental Hygienist Education, Department of Odontology, University of Umeå, SE-90187 Umeå, Sweden. anitha.persson@odont.umu.se
authors.forename: A
authors.initials: A
authors.lastname: Persson
authors.forename: P
authors.initials: P
authors.lastname: Lingstrom
authors.forename: J W V
authors.initials: JW
authors.lastname: van Dijken
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019540:Area Under Curve; D002327:Cariostatic Agents / Q000494:pharmacology; D003188:Composite Resins / Q000737:chemistry*; D003773:Dental Plaque / Q000737:chemistry*; D003793:Dental Restoration, Permanent; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration / Q000187:drug effects; D006878:Hydroxides / Q000494:pharmacology; D008297:Male; D008875:Middle Aged; D011140:Polyurethanes / Q000737:chemistry*
chemical_list: D000180:Acrylic Resins; D002327:Cariostatic Agents; C029012:Composite Dental Resin; D003188:Composite Resins; D006878:Hydroxides; D011140:Polyurethanes; C031356:hydroxide ion