title: Calcium metabolism in cows receiving an intramuscular injection of 1,25-dihydroxyvitamin D3 combined with prostaglandin F(2alpha) closely before parturition.
abstract: To determine the effect of exogenous 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] combined with induced parturition on calcium (Ca) metabolism, cows received a single intramuscular injection of 1,25(OH)2D3 and prostaglandin F(2alpha) (PGF(2alpha)) closely before calving. Ten late-pregnant, multiparous Holstein cows were assigned to 1,25(OH)2D3 group (five treated with both 1,25(OH)2D3 and PGF(2alpha)) and control group (five treated with PGF(2alpha)). 1,25(OH)2D3 group showed an increase in plasma Ca concentration around parturition, whereas control group revealed a decrease in plasma Ca level. Plasma Ca concentration in 1,25(OH)2D3 group were significantly higher than that in control group during -0.5 to 3 days after parturition.
authors.affiliation: Research Center for Animal Hygiene and Food Safety, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan. nori_yamagishi@hotmail.co.jp
authors.forename: Norio
authors.initials: N
authors.lastname: Yamagishi
authors.forename: Yu
authors.initials: Y
authors.lastname: Ayukawa
authors.forename: Inhyung
authors.initials: I
authors.lastname: Lee
authors.forename: Kenji
authors.initials: K
authors.lastname: Oboshi
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Naito
mesh_terms: D000818:Animals; D002117:Calcitriol / Q000494:pharmacology*; D002118:Calcium / Q000097:blood / Q000378:metabolism*; D002417:Cattle / Q000378:metabolism*; D015237:Dinoprost / Q000494:pharmacology*; D004334:Drug Administration Schedule / Q000662:veterinary; D005260:Female; D007273:Injections, Intramuscular / Q000662:veterinary; D008274:Magnesium / Q000097:blood; D010319:Parturient Paresis / Q000517:prevention & control; D036801:Parturition / Q000097:blood / Q000378:metabolism*; D010758:Phosphorus / Q000097:blood; D011247:Pregnancy; D018709:Statistics, Nonparametric
chemical_list: D010758:Phosphorus; D015237:Dinoprost; D002117:Calcitriol; D008274:Magnesium; D002118:Calcium