Growth deficiency in oculodigitoesophagoduodenal (Feingold) syndrome--case report and review of the literature.
We report a case of Feingold syndrome with oesophageal atresia and microcephaly. Marked short stature was present at the age of 9 years. Although short stature has not previously been commented upon as a feature of this syndrome, a review of the literature indicates that it has occurred in several previously reported cases. Of the 18 cases in the literature for which height was recorded, three (16.7%) had height on or below the 0.4th centile, while nine (50%) had height on or below the 10th centile. We suggest that short stature is likely to be a phenotypic feature of Feingold syndrome.
Shaw-Smith
Charles
C
Department of Medical Genetics Cytogenetics, Addenbrooke's Hospital, Cambridge CB2 2QQ Department of Paediatrics, Norfolk and Norwich University Hospital, Colney Lane, Norwich, NR4 7UY.
Willatt
Lionel
L
Thalange
Nandu
N
D000015:Abnormalities, Multiple / Q000235:genetics / Q000473:pathology*; D002648:Child; D004380:Duodenal Obstruction / Q000473:pathology*; D004933:Esophageal Atresia / Q000473:pathology*; D005192:Family Health; D005260:Female; D005385:Fingers / Q000002:abnormalities; D006130:Growth Disorders / Q000473:pathology*; D006228:Hand Deformities, Congenital / Q000473:pathology; D006801:Humans; D008297:Male; D008831:Microcephaly / Q000473:pathology*; D010375:Pedigree; D013577:Syndrome