[The role of morphological characteristics of lymph nodes in differential diagnosis of reactive lymphadenopathies].
OBJECTIVE
To analyse causes of reactive lymphadenitis regarding histological changes in the lymph node, of diagnostic errors; to determine frequency of establishment of nosological diagnosis.


METHODS
A retrospective analysis of diagnostic examination of 375 patients with reactive lymphadenitis observed from 1992 to 2000 was made.


RESULTS
For differential diagnosis 6 groups of reactive lymphadenopathies with different histological picture were identified: follicular hyperplasia, paracortical hyperplasia, granulomatous lymphadenitis, granulomatous pyonecrotic lymphadenitis, sinus histiocytosis as a leading sign and node necrosis as a leading sign. The analysis of making nosological diagnosis for each group and of diagnostic errors was conducted.


CONCLUSIONS
Characteristics of lymph node changes in reactive lymphadenitis is of great importance. Better cooperation between histologists and clinicians must improve efficacy of reactive lymphadenitis diagnosis.
Melikian
A L
AL
Kaplanskaia
I B
IB
Nikitin
E A
EA
Kovaleva
L G
LG
D003937:Diagnosis, Differential; D005497:Follicular Cyst / Q000209:etiology / Q000473:pathology; D020042:Histiocytic Necrotizing Lymphadenitis / Q000209:etiology / Q000473:pathology; D006801:Humans; D007244:Infectious Mononucleosis / Q000175:diagnosis; D008198:Lymph Nodes / Q000473:pathology*; D008206:Lymphatic Diseases / Q000209:etiology / Q000473:pathology*; D008230:Lymphomatoid Granulomatosis / Q000209:etiology / Q000473:pathology; D012189:Retrospective Studies