title: Ultrafast dynamics of resonance energy transfer in cryptochrome.
abstract: In this communication, we report the ultrafast dynamics of resonance energy transfer in a blue-light photoreceptor, Vibrio cholerae cryptochrome. The transfer was observed to occur in 60 ps. We also studied the local rigidity and solvation around the binding site of the photoantenna molecule. The results for the first time show energy transfer in cryptochrome suggesting some mechanistic similarities between photolyase that repairs damaged DNA and cryptochrome that mediates blue-light signaling.
authors.affiliation: Department of Physics, 174 West 18th Avenue, The Ohio State University, Columbus, Ohio 43210, USA.
authors.forename: Chaitanya
authors.initials: C
authors.lastname: Saxena
authors.forename: Haiyu
authors.initials: H
authors.lastname: Wang
authors.forename: I Halil
authors.initials: IH
authors.lastname: Kavakli
authors.forename: Aziz
authors.initials: A
authors.lastname: Sancar
authors.forename: Dongping
authors.initials: D
authors.lastname: Zhong
mesh_terms: D016880:Anisotropy; D056931:Cryptochromes; D004255:Deoxyribodipyrimidine Photo-Lyase / Q000737:chemistry; D004735:Energy Transfer; D005182:Flavin-Adenine Dinucleotide / Q000737:chemistry; D005415:Flavins / Q000737:chemistry; D005420:Flavoproteins / Q000737:chemistry*; D005492:Folic Acid / Q000031:analogs & derivatives* / Q000737:chemistry; D007700:Kinetics; D010084:Oxidation-Reduction; D010777:Photochemistry; D010786:Photoreceptor Cells / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D014734:Vibrio cholerae
chemical_list: D056931:Cryptochromes; D005415:Flavins; D005420:Flavoproteins; D005182:Flavin-Adenine Dinucleotide; C032418:5,11-methenyltetrahydrohomofolate; D005492:Folic Acid; D004255:Deoxyribodipyrimidine Photo-Lyase