Bioactive stilbene dimers from Gnetum cleistostachyum.
Two new stilbene dimers, named bisisorhapontigenin A (1) and cis shegansu B (2), together with gnetuhainin P (3) and gnetulin (4), were isolated from the lianas of Gnetum cleistostachyum C. Y. Cheng. Their structures were elucidated by means of spectroscopic evidences, including UV, IR, MS, 1H NMR, 13C NMR, NOE and 2D NMR, respectively. The pharmacological activities of compounds 1, 2 and 3 also have been tested.
Yao
Chun-Suo
CS
Institute of Material Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Lin
Mao
M
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry* / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology; D002478:Cells, Cultured; D035684:Gnetum / Q000737:chemistry*; D008264:Macrophages / Q000187:drug effects; D051379:Mice; D015394:Molecular Structure; D013267:Stilbenes / Q000737:chemistry* / Q000494:pharmacology*
D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D013267:Stilbenes