Proliferating hemangioma of infancy: successful treatment with topical 5% imiquimod cream.
A 4-month-old girl had a proliferating hemangioma of infancy (infantile hemangioma) affecting the chest wall. The lesion had appeared 1 week after birth, demonstrating both superficial and deep components, and was rapidly enlarging. It had become painful and superficially eroded. Treatment with topical 5% imiquimod cream three times a week was associated with signs of involution after 10 days, and complete resolution after 10 weeks of therapy. The treatment was well tolerated.
Hazen
Paul G
PG
Department of Dermatology, Case-Western Reserve University School of Medicine, Cleveland, Ohio, USA. Paulhazen@aol.com
Carney
James F
JF
Engstrom
Conley W
CW
Turgeon
Karen L
KL
Reep
Michael D
MD
Tanphaichitr
Arrthapol
A
D000287:Administration, Topical; D000634:Aminoquinolines / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005260:Female; D006391:Hemangioma / Q000188:drug therapy*; D006801:Humans; D000077271:Imiquimod; D007223:Infant; D012878:Skin Neoplasms / Q000188:drug therapy*
D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod