title: [Study on space flight-mutants of Monascus purpureus using Random Amplified Polymorphic DNA].
abstract: OBJECTIVE
  To study the mechanism of microbial mutation in aerospace.
  
  
  METHODS
  Random Amplified Polymorphic DNA (RAPD) was used to analyze the polymorphism of high Lovastatin-producing mutants.
  
  
  RESULTS
  Variations occurred in genomes of these mutants.
  
  
  CONCLUSIONS
  The high Lovastatin producibility of the mutants is due to the variation of genomes, therefore the microbial mutation in the aerospace is achieved via the variation of hereditary genes in the microbes.
authors.forename: Hong
authors.initials: H
authors.lastname: Yin
authors.forename: Wei
authors.initials: W
authors.lastname: Lu
authors.forename: Shen-meng
authors.initials: SM
authors.lastname: Xie
mesh_terms: D004271:DNA, Fungal / Q000235:genetics*; D004783:Environmental Microbiology; D008148:Lovastatin / Q000235:genetics / Q000378:metabolism*; D032741:Monascus / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D009154:Mutation; D019105:Random Amplified Polymorphic DNA Technique; D013026:Space Flight; D014893:Weightlessness
chemical_list: D004271:DNA, Fungal; D008148:Lovastatin