N-Benzoyl-N'-dialkylthiourea derivatives and their Co(III) complexes: structure, and antifungal.
N-(Morpholinothiocarbonyl) benzamide (C(12)H(14)N(2)O(2)S) and N-(piperidylthiocarbonyl) benzamide (C(13)H(16)N(2)OS) and their Co(III) complexes have been synthesized and characterized by elemental analysis, FTIR and NMR methods. The complex Co(C(12)H(14)N(2)O(2)S)(3), crystallizes in the triclinic space group P1, with Z=2, and unit cell parameters, a=12.080(7)A, b=12.195(7)A, c=13.025(6)A, alpha=90.198(7) degrees, beta=95.721(7) degrees, gamma=106.426(9) degrees, V=1830.4(17)A(3). The antifungal activity against the major pathogens responsible for important plant diseases (Botrytis cinerea, Myrothecium and Verticillium dahliae dleb) of N-(piperidylthiocarbonyl) benzamide and its complex with cobalt (III) are studied and compared with N-(morpholinothiocarbonyl) benzamide.
Weiqun
Zhou
Z
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Suzhou University, 1 Shizi St., Suzhou 215006, People's Republic of China. wqzhou@suda.edu.cn <wqzhou@suda.edu.cn>
Wen
Yang
Y
Liqun
Xie
X
Xianchen
Cheng
C
D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D018360:Crystallography, X-Ray; D005658:Fungi / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D017550:Spectroscopy, Fourier Transform Infrared; D013890:Thiourea / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
D000935:Antifungal Agents; D009942:Organometallic Compounds; D013890:Thiourea