title: An efficient and simple aqueous N-heterocyclization of aniline derivatives: microwave-assisted synthesis of N-aryl azacycloalkanes.
abstract: [reaction: see text] An efficient and clean synthesis of N-aryl azacycloalkanes from alkyl dihalides and aniline derivatives has been achieved using microwave irradiation in an aqueous potassium carbonate medium. The phase separation can simplify the product isolation and reduce usage of volatile organic solvents.
authors.affiliation: Sustainable Technology Division, National Risk Management Research Laboratory, U.S. Environmental Protection Agency, 26 West Martin Luther King Drive, MS 443, Cincinnati, Ohio 45268, USA.
authors.forename: Yuhong
authors.initials: Y
authors.lastname: Ju
authors.forename: Rajender S
authors.initials: RS
authors.lastname: Varma