title: Newbouldiaquinone and newbouldiamide: a new naphthoquinone-anthraquinone coupled pigment and a new ceramide from Newbouldia laevis.
abstract: Newbouldiaquinone (1), a new naphthoquinone-anthraquinone coupled pigment and a new ceramide named newbouldiamide (2), have been isolated from Newbouldia laevis, besides the known compounds lapachol (3), canthic acid, oleanolic acid, 2-methyl-9,10-anthracenedione, 2-acetylfuro-1,4-naphthoquinone, 2,3-dimethoxy-1,4-benzoquinone, 2-(4-hydroxyphenyl)ethyl triacontanoate, beta-sitosterol and beta-sitosterol glucopyranoside. The structure elucidations of the isolated new compounds were performed on the basis of spectroscopic and chemical evidence. Preliminary studies showed that 1 is moderately antibacterial against Gram-positive Bacillus megaterium and that 3 has moderate herbicidal and antibacterial activities.
authors.affiliation: Department of Organic Chemistry, Yaounde University I, P.O. Box 812, Yaounde, Cameroon.
authors.forename: Kenneth Oben
authors.initials: KO
authors.lastname: Eyong
authors.forename: Karsten
authors.initials: K
authors.lastname: Krohn
authors.forename: Hidayat
authors.initials: H
authors.lastname: Hussain
authors.forename: Gabriel Ngosong
authors.initials: GN
authors.lastname: Folefoc
authors.forename: Augustin Ephram
authors.initials: AE
authors.lastname: Nkengfack
authors.forename: Barbara
authors.initials: B
authors.lastname: Schulz
authors.forename: Qunxiu
authors.initials: Q
authors.lastname: Hu
mesh_terms: D000880:Anthraquinones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D029402:Bignoniaceae; D002518:Ceramides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008826:Microbial Sensitivity Tests / Q000379:methods; D009285:Naphthoquinones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D010860:Pigments, Biological / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018514:Plant Structures
chemical_list: D000880:Anthraquinones; D002518:Ceramides; D009285:Naphthoquinones; D010860:Pigments, Biological; D010936:Plant Extracts