title: Structural and spectral assignment of three forskolin-like diterpenoids isolated from Plectranthus ornatus.
abstract: Three labdane diterpenoids were isolated from an acetone extract of Plectranthus ornatus. Their structures, closely related to that of forskolin, were determined by NMR studies. Unambiguous and complete assignments of the 1H and 13C NMR chemical shifts for these substances are presented. The assignments are based on 2D shift-correlated [1H, 1H-COSY, 1H, 13C-gHSQC-1J (C,H), 1H, 13C-gHMBC-(n)J (C,H) (n = 2 and 3)] and NOE experiments.
authors.affiliation: Faculdade de Farmácia da Universidade de Lisboa, CECF, Av. Prof. Gama Pinto, 1649-003 Lisbon, Portugal.
authors.forename: Patrícia
authors.initials: P
authors.lastname: Rijo
authors.forename: M Fátima
authors.initials: MF
authors.lastname: Simões
authors.forename: Benjamín
authors.initials: B
authors.lastname: Rodríguez
mesh_terms: D002247:Carbon Isotopes; D005576:Colforsin / Q000032:analysis / Q000737:chemistry; D004224:Diterpenes / Q000032:analysis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008968:Molecular Conformation; D010936:Plant Extracts / Q000032:analysis / Q000737:chemistry*; D031346:Plectranthus / Q000378:metabolism*; D011522:Protons
chemical_list: D002247:Carbon Isotopes; D004224:Diterpenes; D010936:Plant Extracts; D011522:Protons; D005576:Colforsin