Enhanced inhibition of transcription start by targeting with 2'-OMe pentaribonucleotides comprising locked nucleic acids and intercalating nucleic acids.
Filichev
Vyacheslav V
VV
Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark.
Vester
Birte
B
Hansen
Lykke H
LH
Abdel Aal
Mohammed T
MT
Babu
B Ravindra
BR
Wengel
Jesper
J
Pedersen
Erik B
EB
D015870:Gene Expression / Q000187:drug effects / Q000235:genetics; D006801:Humans; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides; D016376:Oligonucleotides, Antisense / Q000737:chemistry / Q000187:drug effects*; D009843:Oligoribonucleotides / Q000737:chemistry / Q000235:genetics / Q000494:pharmacology*; D014158:Transcription, Genetic / Q000187:drug effects* / Q000235:genetics
D009841:Oligonucleotides; D016376:Oligonucleotides, Antisense; D009843:Oligoribonucleotides; C477371:locked nucleic acid