title: [Efficiency of lymphatic mapping by intradermal injection of vital blue dye for sentinel node identification in T1-2 N0-1 M0 stage breast cancer patients].
abstract: The lymphatic mapping and sentinel lymphadenectomy procedure is a highly accurate method of axillary staging in breast cancer. Because no other method accurately predicts axillary node status without complete axillary dissection, this technique has a potential to become the standard method of axillary staging for breast cancer in near future. The aim of the study was to evaluate efficiency of lymphatic mapping by intradermal injection of vital blue dye for sentinel node identification in T(1-2) N(0-1) M(0) stage breast cancer patients. The sentinel lymph node biopsy with total axillary dissection was performed in 36 patients. The efficiency of lymphatic mapping by intradermal injection of vital blue dye (identification rate) was 97,2%, specificity--100% and the false-negative rate was 2,8%.
authors.affiliation: Department of Pathomorphology, National Center of Oncology, Tbilisi, Georgia.
authors.forename: I
authors.initials: I
authors.lastname: Kokhreidze
authors.forename: G
authors.initials: G
authors.lastname: Nemsadze
authors.forename: G
authors.initials: G
authors.lastname: Gersamia
authors.forename: G
authors.initials: G
authors.lastname: Dzagnidze
authors.forename: M
authors.initials: M
authors.lastname: Janjalia
mesh_terms: D000328:Adult; D000368:Aged; D001365:Axilla; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D007271:Injections, Intradermal; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000473:pathology; D008751:Methylene Blue / Q000008:administration & dosage*; D008875:Middle Aged; D009367:Neoplasm Staging; D012680:Sensitivity and Specificity; D021701:Sentinel Lymph Node Biopsy / Q000379:methods
chemical_list: D008751:Methylene Blue