title: Evaluation of a continuous glucose monitoring system in cats with diabetes mellitus.
abstract: A continuous glucose monitoring system (CGMS) was evaluated in 14 cats with naturally occurring diabetes mellitus. The device measures interstitial fluid glucose continuously, by means of a sensor placed in the subcutaneous tissue. All cats tolerated the device well and a trace was obtained on 15/16 occasions. There was good correlation between the CGMS values and blood glucose concentration measured using a glucometer (r=0.932, P<0.01). Limitations to the use of the CGMS are its working glucose range of 2.2-22.2 mmol/l (40-400 mg/dl) and the need for calibration with a blood glucose measurement at least every 12 h. When compared to a traditional blood glucose curve, the CGMS is minimally invasive, reduces the number of venepunctures necessary to assess the kinetics of insulin therapy in a patient and provides a truly continuous glucose curve.
authors.affiliation: Axiom Veterinary Laboratories, Teignmouth, Devon TQ14 8AH, UK. jelena.ristic@axiomvetlab.co.uk
authors.forename: Jelena M E
authors.initials: JM
authors.lastname: Ristic
authors.forename: Michael E
authors.initials: ME
authors.lastname: Herrtage
authors.forename: Sabine M M
authors.initials: SM
authors.lastname: Walti-Lauger
authors.forename: Linda A
authors.initials: LA
authors.lastname: Slater
authors.forename: David B
authors.initials: DB
authors.lastname: Church
authors.forename: Lucy J
authors.initials: LJ
authors.lastname: Davison
authors.forename: Briän
authors.initials: B
authors.lastname: Catchpole
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D015190:Blood Glucose Self-Monitoring / Q000379:methods / Q000662:veterinary*; D002138:Calibration; D002371:Cat Diseases / Q000097:blood*; D002415:Cats; D003920:Diabetes Mellitus / Q000097:blood / Q000662:veterinary*; D005260:Female; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D001786:Blood Glucose