title: Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?
authors.affiliation: Max-Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany. zorbas@bio-m.de
authors.forename: Haralabos
authors.initials: H
authors.lastname: Zorbas
authors.forename: Bernhard K
authors.initials: BK
authors.lastname: Keppler
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology* / Q000633:toxicity; D002945:Cisplatin / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology* / Q000633:toxicity; D004247:DNA / Q000187:drug effects / Q000235:genetics / Q000378:metabolism; D018736:DNA Adducts / Q000378:metabolism; D004260:DNA Repair / Q000502:physiology*; D051747:DNA-Activated Protein Kinase; D004268:DNA-Binding Proteins / Q000378:metabolism; D024002:HMGB Proteins / Q000378:metabolism; D006801:Humans; D009687:Nuclear Proteins; D011065:Poly(ADP-ribose) Polymerases / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents; D018736:DNA Adducts; D004268:DNA-Binding Proteins; D024002:HMGB Proteins; D009687:Nuclear Proteins; C057270:cisplatin-DNA adduct; D004247:DNA; D011065:Poly(ADP-ribose) Polymerases; D051747:DNA-Activated Protein Kinase; C497263:PRKDC protein, human; D017346:Protein Serine-Threonine Kinases; D002945:Cisplatin