title: Prevalence of strongyloides in Northern Thailand and treatment with ivermectin vs albendazole.
abstract: The stools of 697 cases were examined by agar plate technique at Tambon Makam Luang, Sun Pa Tong district, Chiang Mai; there were Strongyloides stercoralis 15.9%,Opisthorchis viverrini 5.1%, intestinal fluke 0.1%. Treatment with ivermectin 78 cases and albendazole 33 cases of strongyloidiasis gave cure rates at 98.7% and 78.7%, respectively. Alkaline phosphatase in some patients were increased at mild level after treatment. Side effects in ivermectin group were anorexia, nausia, diarrhea, diffuse itching and drowsiness; and in albendazole group were nausia and diarrhea. The efficacy of single dose and mild side effects suggest ivermectin as drug of choice for strongyloidiasis treatment.
authors.affiliation: Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
authors.forename: Ponganant
authors.initials: P
authors.lastname: Nontasut
authors.forename: Chatree
authors.initials: C
authors.lastname: Muennoo
authors.forename: Surapol
authors.initials: S
authors.lastname: Sa-nguankiat
authors.forename: Sutep
authors.initials: S
authors.lastname: Fongsri
authors.forename: Adulsak
authors.initials: A
authors.lastname: Vichit
mesh_terms: D015766:Albendazole / Q000009:adverse effects / Q000627:therapeutic use*; D000818:Animals; D000871:Anthelmintics / Q000009:adverse effects / Q000627:therapeutic use*; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D007559:Ivermectin / Q000009:adverse effects / Q000627:therapeutic use*; D008111:Liver Function Tests; D008297:Male; D015995:Prevalence; D017678:Sex Distribution; D013321:Strongyloides / Q000187:drug effects* / Q000302:isolation & purification; D013322:Strongyloidiasis / Q000188:drug therapy* / Q000453:epidemiology; D013785:Thailand / Q000453:epidemiology
chemical_list: D000871:Anthelmintics; D007559:Ivermectin; D015766:Albendazole