title: Deep brain stimulation to relieve drug-resistant SUNCT.
abstract: The rare primary headache short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) is characterized by 3 to 200 attacks per day of severe unilateral orbital pain. Functional magnetic resonance imaging shows increased blood flow in the ipsilateral posterior inferior hypothalamus during attacks, indicating activation. We report the first patient with SUNCT in whom severe intractable pain (70 per day) was well controlled by electrode implant to and continuous stimulation of the posterior inferior hypothalamus. Ann Neurol 2005;57:925-927.
authors.affiliation: Department of Neurology and Headache Centre, Milano, Italy. leone@istituto-besta.it
authors.forename: Massimo
authors.initials: M
authors.lastname: Leone
authors.forename: Angelo
authors.initials: A
authors.lastname: Franzini
authors.forename: Giovanni
authors.initials: G
authors.lastname: D'Andrea
authors.forename: Giovanni
authors.initials: G
authors.lastname: Broggi
authors.forename: Gerardo
authors.initials: G
authors.lastname: Casucci
authors.forename: Gennaro
authors.initials: G
authors.lastname: Bussone
mesh_terms: D000368:Aged; D003229:Conjunctival Diseases / Q000209:etiology / Q000628:therapy*; D046690:Deep Brain Stimulation; D004351:Drug Resistance; D005260:Female; D020773:Headache Disorders / Q000150:complications / Q000628:therapy*; D006801:Humans; D007034:Hypothalamus, Posterior / Q000502:physiology*; D013666:Tears