Recent studies in novel therapy for metastatic sarcomas.
Many new chemotherapeutic agents and targeted therapies are being studied in the treatment of metastatic soft tissue sarcomas (STSs). This article reviews results of recent clinical studies of gemcitabine, docetaxel, paclitaxel, ecteinascidin, 9-nitrocamptothecin, and pegylated liposomal doxorubicin, in patients who have STSs. The use of targeted therapy in STSs is an exciting, constantly changing field. The activity of imatinib mesylate, SU11248, everolimus, and bortezomib are summarized.
Steinert
Dejka M
DM
Division of Cancer Medicine, The University of Texas, MD Anderson Cancer Center, Unit 10, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
Patel
Shreyaskumar R
SR
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D012509:Sarcoma / Q000188:drug therapy* / Q000556:secondary*
D000970:Antineoplastic Agents