Sex and the single splice.
Drosophila male courtship offers a unique experimental system to uncover the molecular and neural basis of genetically preprogrammed behavior. In this issue of Cell, Demir and Dickson (2005) and Stockinger et al. (2005) demonstrate that this behavior relies on a single splicing of the fruitless transcript, and on a specific olfactory-based neuronal circuit.
Dulac
Catherine
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Howard Hughes Medical Institute, Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.
D017398:Alternative Splicing; D000818:Animals; D029721:Drosophila Proteins / Q000235:genetics* / Q000378:metabolism; D004331:Drosophila melanogaster / Q000235:genetics*; D008297:Male; D009419:Nerve Tissue Proteins / Q000235:genetics* / Q000378:metabolism; D009474:Neurons / Q000378:metabolism; D012726:Sexual Behavior, Animal; D014157:Transcription Factors / Q000235:genetics* / Q000378:metabolism
D029721:Drosophila Proteins; D009419:Nerve Tissue Proteins; D014157:Transcription Factors; C103226:fru protein, Drosophila