title: A high-resolution voxel phantom of the breast for dose calculations in mammography.
abstract: Though mammography is one of the most sensitive methods to detect breast cancer, the benefit of the mammography screening programmes is still not clearly proven. One of the reasons is the radiation dose delivered by the examinations. Simulations of the radiation transport based on realistic breast phantoms are a useful tool to estimate the dose for the risk relevant parenchymal tissue. Specimens of real breasts have been fixated using a specially designed process while being compressed as in mammography. They have been scanned using the high-resolution mode of a CT. A segmentation has been carried out by assigning the voxels to different tissues. The resulting voxel phantom allows the assessment of tissue doses by Monte-Carlo calculations and can be used to simulate the diagnostic outcome of different imaging procedures. Three different tissues were separated: skin, adipose and 'breast tissue'. This allows reasonable calculations of the average glandular doses in mammography.
authors.affiliation: Department for Diagnostic Radiology, University Hospital Magdeburg, Leipziger Strasse 44, 39120 Magdeburg, Germany. Christoph.Hoeschen@gsf.de
authors.forename: Christoph
authors.initials: C
authors.lastname: Hoeschen
authors.forename: Ute
authors.initials: U
authors.lastname: Fill
authors.forename: Maria
authors.initials: M
authors.lastname: Zankl
authors.forename: Werner
authors.initials: W
authors.lastname: Panzer
authors.forename: Dieter
authors.initials: D
authors.lastname: Regulla
authors.forename: Wilfried
authors.initials: W
authors.lastname: Döhring
mesh_terms: D000273:Adipose Tissue / Q000000981:diagnostic imaging; D000368:Aged; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000473:pathology; D005260:Female; D006801:Humans; D008327:Mammography / Q000295:instrumentation* / Q000379:methods*; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000295:instrumentation* / Q000379:methods*; D011874:Radiometry / Q000379:methods; D012867:Skin / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*; D014963:X-Ray Intensifying Screens