title: [Miller-Fisher syndrome].
abstract: BACKGROUND
  Miller-Fisher syndrome is characterised by the clinical triad of ophthalmoplegia, ataxia and areflexia and is considered a variant form of Guillain-Barré syndrome. In western countries the incidence is reported to be approximately 1-5% that of Guillain-Barré syndrome. Approximately 90% of patients have antibodies against the ganglioside GQ1b, which is of diagnostic and pathogenic importance.
  
  
  METHODS
  We present two patients with Miller-Fisher syndrome and describe clinical features and possible mechanisms of GQ1b antibodies.
  
  
  CONCLUSIONS
  Both patients presented with the classical triad of symptoms and GQ1b antibodies after upper respiratory tract infections. One of the patients had a more severe form with additional bulbar signs and was treated with plasma exchange. Both made almost complete recoveries within a few months.
authors.affiliation: Nevrologisk avdeling, Haukeland Universitetssykehus, 5021 Bergen. joergensenlisa@hotmail.com
authors.forename: Lisa
authors.initials: L
authors.lastname: Jørgensen
authors.forename: Christian A
authors.initials: CA
authors.lastname: Vedeler
mesh_terms: D000368:Aged; D000906:Antibodies / Q000032:analysis; D005732:Gangliosides / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D019846:Miller Fisher Syndrome / Q000175:diagnosis / Q000235:genetics / Q000276:immunology
chemical_list: D000906:Antibodies; D005732:Gangliosides; C039129:GQ1b ganglioside