Primate spondyloarthropathy.
Spondyloarthropathy is a common occurrence in Old World primates, with only limited presence in New World monkeys. Clearly distinguished from rheumatoid arthritis, this erosive arthritis afflicts 20% of great apes, baboons, and rhesus macaques and had been increasing in frequency. Habitat-dependent infectious agent diarrhea-induced reactive arthritis is implicated on a background of genetic predisposition. A gorilla-derived therapeutic preventative approach has possible application in human clinical medicine.
Rothschild
Bruce M
BM
Arthritis Center of Northeast Ohio, 5500 Market Street, Youngstown, OH 44512, USA. bmr@neoucom.edu
D000818:Animals; D004195:Disease Models, Animal; D015994:Incidence; D018419:Primate Diseases / Q000145:classification / Q000453:epidemiology; D011323:Primates; D025242:Spondylarthropathies / Q000145:classification / Q000453:epidemiology / Q000662:veterinary*