H-reflex and motor responses to acute ischemia in apparently healthy individuals.
The authors examined the effect of acute ischemia on peripheral nerve function in healthy subjects. It was hypothesized that acute ischemia would interfere with the ability of sensory and motor nerves to propagate an impulse. Twelve young, apparently healthy adults participated in the study. Soleus H-reflex and motor recruitment curves were determined for subjects during a control condition, after 5 minutes of ischemia by femoral artery occlusion, and after a 5-minute recovery. During ischemia, the stimulus intensity required to evoke an H-reflex or M-wave was reduced by 18.3% and 18.4%, respectively. Hmax/Mmax ratios were significantly reduced with acute ischemia (mean +/- standard error) 66.29% +/- 5.4% and 58.81% +/- 6.7% for control and ischemia, respectively, owing to a decrease in Hmax during acute ischemia with no change in Mmax. After ischemia, the Hmax/Mmax returned to control values, as did the M-threshold. However, although the H-threshold slightly recovered, it failed to return to control threshold after 5 minutes of recovery. The results suggest that acute ischemia decreases motor and H-reflex thresholds in healthy individuals with a longer lasting effect for the H-reflex. In addition, a decrease in Hmax/Mmax ratio was observed, suggesting that acute ischemia has differential effects on sensory nerve propagation and synapse transmission.
Zakutansky
Donald W
DW
Clinical Exercise Physiology Laboratory, Indiana University, Bloomington, Indiana 47405, USA.
Kitano
Koichi
K
Wallace
Janet P
JP
Koceja
David M
DM
D000208:Acute Disease; D000328:Adult; D004558:Electric Stimulation / Q000379:methods; D004576:Electromyography / Q000379:methods; D019054:Evoked Potentials, Motor / Q000502:physiology / Q000528:radiation effects; D005260:Female; D006181:H-Reflex / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D007511:Ischemia / Q000503:physiopathology*; D008297:Male; D009043:Motor Activity / Q000502:physiology* / Q000528:radiation effects; D018482:Muscle, Skeletal / Q000503:physiopathology / Q000528:radiation effects; D011999:Recruitment, Neurophysiological / Q000502:physiology / Q000528:radiation effects; D012684:Sensory Thresholds / Q000502:physiology* / Q000528:radiation effects; D009435:Synaptic Transmission / Q000502:physiology / Q000528:radiation effects