[Expression and distribution of aquaporin-5 in human nasal polyps].
OBJECTIVE
To investigate the distribution and expression of aquaporin-5 (AQP-5) in nasal polyps and explore the role of AQP-5 in the formation of nasal polyps and the normal function of AQP-5 in the inferior turbinate.


METHODS
AQP-5 were studied in 30 samples nasal polyps and 12 samples of inferior turbinates with immunochemistric staing.


RESULTS
The level of AQP-5 positive cells in the serous cells from nasal polyps were lesser than that from inferior turbinate, and the level of AQP-5 positive cells in the blood vessel endothelium from nasal polyps were more than that from inferior turbinate.


CONCLUSIONS
AQP-5 may play the role in both the formation of nasal polyps and the function of normal nasal mucous membrane.
Li
Zhihai
Z
Department of Otolaryngology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. Lioohai@163.com
Gao
Qixue
Q
D000293:Adolescent; D000328:Adult; D000368:Aged; D051402:Aquaporin 5 / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000378:metabolism* / Q000473:pathology; D014420:Turbinates / Q000378:metabolism
D051402:Aquaporin 5