title: [(CAG) n polymorphism of androgen receptor gene in idiopathic azoospermic and oligospermic Chinese men].
abstract: OBJECTIVE
  To research (CAG)n polymorphism of androgen receptor gene in idiopathic azoospermic and oligospermic Chinese men, and to explore its correlation with the development of dyszoospermia.
  
  
  METHODS
  Fifty-two men with oligospermia and 31 with azoospermia were enrolled, the number of CAG sequence repeats determined by PCR and denaturing polyacrylamide gel electrophoresis (PAGE), and (CAG)n polymorphism analyzed.
  
  
  RESULTS
  The CAG repeats in the men with oligospermia and those with azoospermia were 22.19 and 22.13 respectively.
  
  
  CONCLUSIONS
  The polymorphism of the repeat length of the (CAG) n satellite in androgen receptor gene may affect spermatogenesis and have a less important role in male infertility.
authors.affiliation: Peking Union Medical College, Beijing 100730, China.
authors.forename: Zuo-Xiang
authors.initials: ZX
authors.lastname: Li
authors.forename: Wen-Hao
authors.initials: WH
authors.lastname: Tang
authors.forename: Zhao-Hui
authors.initials: ZH
authors.lastname: Wang
authors.forename: Lin
authors.initials: L
authors.lastname: Wang
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Wang
authors.forename: Lu-Lin
authors.initials: LL
authors.lastname: Ma
authors.forename: Xu
authors.initials: X
authors.lastname: Ma
mesh_terms: D000328:Adult; D004591:Electrophoresis, Polyacrylamide Gel; D005091:Exons; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D008297:Male; D009845:Oligospermia / Q000235:genetics; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011944:Receptors, Androgen / Q000235:genetics*; D018911:Trinucleotide Repeats / Q000235:genetics*
chemical_list: D011944:Receptors, Androgen