title: [Abnormalities in tattooed skin: sometimes sarcoidosis].
abstract: A 43-year-old man presented with a nodular tattoo lesion on his right upperarm. Histologically it resembled the granulomatous reaction seen in systemic sarcoidosis. Further evaluation revealed asymmetrical hilar lymphadenopathy with no interstitial lung disease. Since the patient was a heavy smoker, bronchus carcinoma could not be excluded and cervical mediastinoscopy was performed in order to obtain a lymph-node biopsy. This confirmed the diagnosis of systemic sarcoidosis. The patient was treated by local application of corticosteroids, but with little result. Skin lesions in scars or tattoos may be the first symptom of systemic sarcoidosis. Skin biopsy for histological confirmation of the diagnosis is recommended, as is further investigation to evaluate other organ systems which may be affected.
authors.affiliation: Afd. Interne Geneeskunde, Ikazia Ziekenhuis, Montessoriweg 1, 3083 AN Rotterdam. geushrhde@yahoo.com
authors.forename: H R H
authors.initials: HR
authors.lastname: de Geus
authors.forename: R W M
authors.initials: RW
authors.lastname: Giard
authors.forename: F A H
authors.initials: FA
authors.lastname: Jacobs
authors.forename: E R
authors.initials: ER
authors.lastname: Lonnee
authors.forename: A
authors.initials: A
authors.lastname: Dees
mesh_terms: D000287:Administration, Topical; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D012507:Sarcoidosis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D012867:Skin / Q000473:pathology*; D012871:Skin Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D013653:Tattooing; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones