Intractable hiccup as the initial presenting feature of systemic lupus erythematosus.
An infarctus of medulla oblongata was discovered in a 44-year old man with an intractable hiccup and 10, 11th and 12th right cranial nerves palsies. Systemic lupus erythematosus (SLE) with antiphospholipid syndrome was subsequently diagnosed. Hiccup has withdrew with corticosteroid therapy and low-dose aspirin. The other cases of literature and pathophysiologic hypotheses are briefly reported.
Delèvaux
I
I
Department of Internal Medicine, CHU de Clermont-Ferrand, Hôpital G. Montpied, Clermont-Ferrand, France. idelevaux@chu-clermontferrand.fr
André
M
M
Marroun
I
I
Lamaison
D
D
Piette
J C
JC
Aumaître
O
O
D020436:Accessory Nerve Diseases / Q000150:complications; D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications; D002544:Cerebral Infarction / Q000150:complications / Q000175:diagnosis; D006606:Hiccup / Q000209:etiology*; D006801:Humans; D020437:Hypoglossal Nerve Diseases / Q000150:complications; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008279:Magnetic Resonance Imaging; D008297:Male; D008526:Medulla Oblongata / Q000098:blood supply / Q000473:pathology; D010243:Paralysis / Q000150:complications; D020421:Vagus Nerve Diseases / Q000150:complications