title: [Efficacy of to'thema in the treatment of iron deficiency anemia in early childhood with concomitant copper deficiency].
abstract: IDA is still the major medico-social problem in pediatric hematology, especially in early childhood. In this correction ferroresistant forms of IDA are interesting. The aim of our investigation was: studying the Efficacy of Tot'hema in the treatment of Iron Deficiency Anemia in Early childhood with concomitant copper deficiency. We observed 42 patients with IDA (age 0,4 - 3 years) in open control investigation. The carried-out investigations revealed that IDA in early childhood is often proceeded by the concomitant copper deficiency and ceruloplasmin, mainly in premature infants and in children with prolonged diarrhea in anamnesis. In such cases it is important to investigate the copper metabolism together with the peripheral blood index and iron metabolism. Tot'hema improves hematologic and biochemical index, completely supplies iron and copper deficiency, prevents of iron resistant form of IDA. Tot'hema has no side effects.
authors.affiliation: I. Pagava Research Institute of Pediatrics, Tbilisi, Georgia; Tbilisi State Medical University, department of Pediatric and Adolescent Medicine.
authors.forename: Z
authors.initials: Z
authors.lastname: Mtvarelidze
authors.forename: A
authors.initials: A
authors.lastname: Kvezereli-Kopadze
authors.forename: M
authors.initials: M
authors.lastname: Kvezereli-Kopadze
authors.forename: K
authors.initials: K
authors.lastname: Pagava
mesh_terms: D000284:Administration, Oral; D018798:Anemia, Iron-Deficiency / Q000097:blood / Q000188:drug therapy*; D002570:Ceruloplasmin / Q000172:deficiency; D002675:Child, Preschool; D003300:Copper / Q000097:blood / Q000172:deficiency*; D005260:Female; D005500:Follow-Up Studies; D006397:Hematinics / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D007501:Iron / Q000097:blood; D008297:Male; D016896:Treatment Outcome
chemical_list: D006397:Hematinics; D003300:Copper; D007501:Iron; D002570:Ceruloplasmin