Cytotoxic allyl retrochalcone from the roots of Glycyrrhiza inflata.
Two known retrochalcones, licochalcone A (1) and licochalcone C (2), and one new retrochalcone, licochalcone E (4) were isolated by cytotoxicity-guided fractionation from the roots of Glycyrrhiza inflata along with an ordinary chalcone, isoliquiritigenin (3). The structure of the new retrochalcone was elucidated through a spectroscopic analysis.
Yoon
Goo
G
College of Pharmacy & Drug Development Research Institute, Chonnam National University, Gwangju 501-757, Korea.
Jung
Young Do
YD
Cheon
Seung Hoon
SH
D045744:Cell Line, Tumor; D047188:Chalcones / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity*; D003603:Cytotoxins / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity*; D006035:Glycyrrhiza / Q000633:toxicity*; D006801:Humans; D018517:Plant Roots
D047188:Chalcones; D003603:Cytotoxins