[Significance of homocysteines in the development of acute myocardial infarction].
The aim was the study of the connection of the changes in serum homocysteine concentration with acute myocardium infarction, in order to establish whether the increase in homocysteine concentration is one of the risk-factors in the development of the cardiac insufficiency. The patients with acute myocardial infarction were studied. The following tests were performed: determination of the homocysteine concentration in serum by ELISA; determination of the main characteristics of hemostasis by automatic coagulometer (AMELUNG); determination of lipid spectrum by biochemical analyzer (Johnson & Johnson Vitros DT). The results obtained allowed us to suggest that the changes in the serum homocysteine concentration in patients with myocardial infarction occur in accordance with the changes in the protective mechanisms of the organism, and it may be used for the diagnostics of weakening and strengthening of the processes of arteriosclerosis and thrombosis.
Chaava
M
M
Department of Clinical Laboratory Diagnostics, Tbilisi State Medical Academy, Georgia.
Bukia
T
T
Gogokhia
N
N
D015415:Biomarkers; D018450:Disease Progression; D004797:Enzyme-Linked Immunosorbent Assay; D005500:Follow-Up Studies; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D009203:Myocardial Infarction / Q000097:blood* / Q000209:etiology*; D012307:Risk Factors; D012720:Severity of Illness Index
D015415:Biomarkers; D006710:Homocysteine