Design, construction, and intracellular activation of an intramolecularly self-silenced signal transduction inhibitor.
Lee
Seung-Yub
SY
Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.
Liang
Fubo
F
Guo
Xiao-Ling
XL
Xie
Laiping
L
Cahill
Sean M
SM
Blumenstein
Michael
M
Yang
Heyi
H
Lawrence
David S
DS
Zhang
Zhong-Yin
ZY
D000818:Animals; D016466:CHO Cells; D006224:Cricetinae; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D015394:Molecular Structure; D054562:Protein Tyrosine Phosphatase, Non-Receptor Type 1; D017027:Protein Tyrosine Phosphatases / Q000037:antagonists & inhibitors / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects*
D004791:Enzyme Inhibitors; D054562:Protein Tyrosine Phosphatase, Non-Receptor Type 1; D017027:Protein Tyrosine Phosphatases