title: Dose-response relationships for radicals trapped in irradiated solids.
abstract: This work develops a modified description of the dose-response relationships for radical production by ionizing radiation. The main new feature is incorporation of the concept of the target and the possibility that the population of targets can undergo depletion at increased doses. The resulting mathematical relationships are capable of describing the decrease in product yield at increasing doses as is sometime observed. In addition, the description preserves the general properties of the widely used relationships. Finally, the expressions provide the possibility for estimating the average mass of the target.
authors.affiliation: Department of Physics and Astronomy, Georgia State University, Atlanta, Georgia 30303, USA. wnelson@gsu.edu
authors.forename: William H
authors.initials: WH
authors.lastname: Nelson
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry* / Q000528:radiation effects*; D001704:Biopolymers / Q000737:chemistry* / Q000528:radiation effects*; D001822:Body Burden; D003198:Computer Simulation; D004307:Dose-Response Relationship, Radiation; D005609:Free Radicals / Q000737:chemistry / Q000528:radiation effects; D018499:Linear Energy Transfer / Q000502:physiology*; D008954:Models, Biological; D008956:Models, Chemical; D015233:Models, Statistical; D011829:Radiation Dosage; D011874:Radiometry / Q000379:methods*; D012062:Relative Biological Effectiveness
chemical_list: D001672:Biocompatible Materials; D001704:Biopolymers; D005609:Free Radicals