title: Evaluation of vascular supply with angio-computed tomography during intra-arterial chemotherapy for brain tumors.
abstract: We report the utility of a combined angiography and computed tomography (angio-CT) system in assessing drug distribution to the tumor during intra-arterial chemotherapy for metastatic brain tumors in a 65-year-old man. Although digital subtraction angiography did not clearly show tumor perfusion in two cerebellar tumors, angio-CT provided definite tumor perfusion in the complicated vascular territory, and anticancer agents were infused based on its findings. To our knowledge, however, this application for intra-arterial chemotherapy of brain tumors has not been previously described.
authors.affiliation: Department of Radiology, Kumamoto University School of Medicine, 1-1-1 Honjo, Kumamoto 860-8556, Japan. toshinor@beige.ocn.ne.jp
authors.forename: Toshinori
authors.initials: T
authors.lastname: Hirai
authors.forename: Yukunori
authors.initials: Y
authors.lastname: Korogi
authors.forename: Ken
authors.initials: K
authors.lastname: Ono
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Yamashita
mesh_terms: D000368:Aged; D000792:Angiography; D015901:Angiography, Digital Subtraction; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001480:Basal Ganglia Diseases / Q000188:drug therapy / Q000473:pathology; D001932:Brain Neoplasms / Q000098:blood supply / Q000188:drug therapy* / Q000556:secondary; D002528:Cerebellar Neoplasms / Q000098:blood supply / Q000188:drug therapy / Q000556:secondary; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use*; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D015641:Radiography, Interventional; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin