Ectopic pregnancies and reproductive capacity after Chlamydia trachomatis positive and negative test results: a historical follow-up study.
BACKGROUND
Recent studies have shown that women with Chlamydia trachomatis-positive test results worry about their future fertility.


OBJECTIVE
The goal of this study was to give women infected with C. trachomatis a fertility prognosis by analyzing ectopic pregnancies and birth rates


METHODS
An historical follow-up study in a cohort of 22,264 women tested for the infection was conducted.


RESULTS
Cox regression analysis with time-dependent covariates showed that women with at least 1 C. trachomatis-positive test result had a lower incidence rate of ectopic pregnancy than women with negative test results only (adjusted hazard ratio, 0.55; 95% confidence interval [CI], 0.31-0.96). We found comparable birth rates in the 2 groups (adjusted hazard ratio, 0.92; 95% CI, 0.84-1.00).


CONCLUSIONS
Counseling of women with a C. trachomatis-positive test result should emphasize the benefit of detection and treatment of the infection in terms of future morbidity.
Andersen
Berit
B
Research Unit for General Practice, Aarhus, Denmark. ba@alm.au.dk
Østergaard
Lars
L
Puho
Erzsebet
E
Skriver
Mette Vinther
MV
Schønheyder
Henrik C
HC
D000328:Adult; D001723:Birth Rate; D002690:Chlamydia Infections / Q000150:complications*; D002692:Chlamydia trachomatis; D015331:Cohort Studies; D003718:Denmark / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology / Q000209:etiology; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000453:epidemiology* / Q000209:etiology*; D016016:Proportional Hazards Models; D012042:Registries