title: Bioabatement to remove inhibitors from biomass-derived sugar hydrolysates.
abstract: Bioabatement is a potential method to remove inhibitory compounds from lignocellulose hydrolysates that could be incorporated into a scheme for fermentation of ethanol from cellulose. Coniochaeta ligniaria NRRL30616, an Ascomycete that metabolizes furfural and 5-hydroxymethylfurfural, is a unique strain that may be useful for detoxifying biomass sugars. NRRL30616 and 23 related fungal strains were screened for the ability to metabolize furans and grow in dilute-acid hydrolysate of corn stover. NRRL30616 was the best strain for removal of inhibitors from hydrolysate, and abatement of hydrolysate by inoculation with the strain allowed subsequent yeast fermentation of cellulose to ethanol.
authors.affiliation: Fermentation Biotechnology Research Unit, NCAUR, USDA-ARS, 1815 N. University Street, Peoria, IL 61604, USA. nicholnn@ncaur.usda.gov
authors.forename: Nancy N
authors.initials: NN
authors.lastname: Nichols
authors.forename: Bruce S
authors.initials: BS
authors.lastname: Dien
authors.forename: Gema M
authors.initials: GM
authors.lastname: Guisado
authors.forename: Maria J
authors.initials: MJ
authors.lastname: López
mesh_terms: D001203:Ascomycota / Q000145:classification / Q000254:growth & development* / Q000378:metabolism*; D001673:Biodegradation, Environmental; D050260:Carbohydrate Metabolism; D002482:Cellulose / Q000378:metabolism*; D000431:Ethanol / Q000378:metabolism*; D005662:Furaldehyde / Q000378:metabolism*; D006868:Hydrolysis; D008031:Lignin / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000254:growth & development / Q000378:metabolism; D013045:Species Specificity; D003313:Zea mays / Q000382:microbiology*
chemical_list: C036909:lignocellulose; D000431:Ethanol; D002482:Cellulose; D008031:Lignin; D005662:Furaldehyde