Use of nanobarcodes particles in bioassays.
We have developed striped metal nanoparticles, Nanobarcodes particles, which can act as encoded substrates in multiplexed assays. These particles are metallic, encodeable, machine-readable, durable, submicron-sized tags. The power of this technology is that the particles are intrinsically encoded by virtue of the difference in reflectivity of adjacent metal stripes. This chapter describes protocols for the attachment of biological molecules, and the subsequent use of the Nanobarcodes particles in bioassays.
Freeman
R Griffith
RG
Nanoplex Technologies Inc., Menlo Park, CA, USA.
Raju
Paul A
PA
Norton
Scott M
SM
Walton
Ian D
ID
Smith
Patrick C
PC
He
Lin
L
Natan
Michael J
MJ
Sha
Michael Y
MY
Penn
Sharron G
SG
D000818:Animals; D020869:Gene Expression Profiling / Q000379:methods*; D006801:Humans; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D009841:Oligonucleotides / Q000737:chemistry*
D009841:Oligonucleotides