title: Genomic islands in the Corynebacterium efficiens genome.
abstract: Corynebacterium efficiens is a gram-positive nonpathogenic bacterium which can grow and produce glutamate at 40 degrees C or above. By using the cumulative GC profile method, we have identified four genomic islands which have many unifying genomic island-specific features in the C. efficiens genome. The presence of the gene encoding an aspartate kinase in a genomic island helps explain the unexpected low thermal stability of this enzyme; i.e., the adaptive mutations have not occurred extensively due to the recent horizontal gene transfer.
authors.affiliation: Department of Epidemiology and Biostatistics, Tianjin Cancer Institute and Hospital, China.
authors.forename: Ren
authors.initials: R
authors.lastname: Zhang
authors.forename: Chun-Ting
authors.initials: CT
authors.lastname: Zhang
mesh_terms: D001222:Aspartate Kinase / Q000235:genetics; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics; D001482:Base Composition; D001483:Base Sequence; D003352:Corynebacterium / Q000201:enzymology* / Q000235:genetics; D004795:Enzyme Stability; D016680:Genome, Bacterial; D044404:Genomic Islands / Q000235:genetics; D006358:Hot Temperature; D008969:Molecular Sequence Data
chemical_list: D001426:Bacterial Proteins; D001222:Aspartate Kinase