title: Bioactive stilbene dimers from Gnetum cleistostachyum.
abstract: Two new stilbene dimers, named bisisorhapontigenin A (1) and cis shegansu B (2), together with gnetuhainin P (3) and gnetulin (4), were isolated from the lianas of Gnetum cleistostachyum C. Y. Cheng. Their structures were elucidated by means of spectroscopic evidences, including UV, IR, MS, 1H NMR, 13C NMR, NOE and 2D NMR, respectively. The pharmacological activities of compounds 1, 2 and 3 also have been tested.
authors.affiliation: Institute of Material Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
authors.forename: Chun-Suo
authors.initials: CS
authors.lastname: Yao
authors.forename: Mao
authors.initials: M
authors.lastname: Lin
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry* / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology; D002478:Cells, Cultured; D035684:Gnetum / Q000737:chemistry*; D008264:Macrophages / Q000187:drug effects; D051379:Mice; D015394:Molecular Structure; D013267:Stilbenes / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D013267:Stilbenes