Regeneration of urologic tissues and organs.
Patients suffering from a variety of urologic diseases may be treated with transplanted tissues and organs. However, there is a shortage of donor tissues and organs, which is worsening yearly owing to the ageing population. Scientists in the field of regenerative medicine and tissue engineering are applying the principles of cell transplantation, material science, and bioengineering to construct biological substitutes that will restore and maintain normal function in diseased and injured urologic tissues. This chapter reviews recent advances that have occurred in the regeneration of urologic organs and describes how these applications may offer novel therapies for patients with urologic disease.
Atala
Anthony
A
Department of Urology, Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA. aatala@wfubmc.edu
D019976:Cloning, Organism; D006801:Humans; D012038:Regeneration; D013234:Stem Cells / Q000166:cytology; D014566:Urogenital System / Q000502:physiology*