title: Sequential MR imaging and SPECT studies in herpes simplex encephalitis with crossed cerebellar hyperperfusion.
abstract: We report a case of herpes simplex encephalitis in which sequential MR imaging and SPECT studies showed interesting findings. SPECT in the acute stage showed wide increased uptake in the left cerebral hemisphere, as well as increased uptake in the contralateral right cerebellar hemisphere. T1-weighted images in the subacute stage showed hyperintense signals along the cerebral cortices, but T2*-weighted gradient-echo images did not show any signal decrease caused by the magnetic susceptibility effect of hemoglobin degradation. Sequential SPECT studies in addition to MR imaging facilitate precise understanding of the pathophysiology of herpes simplex encephalitis.
authors.affiliation: Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University, Nishicho, Yonago, Japan.
authors.forename: Motoki
authors.initials: M
authors.lastname: Ametani
authors.forename: Toshihide
authors.initials: T
authors.lastname: Ogawa
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Tanabe
authors.forename: Shuji
authors.initials: S
authors.lastname: Sugihara
authors.forename: Fumiko
authors.initials: F
authors.lastname: Kinoshita
authors.forename: Toshibumi
authors.initials: T
authors.lastname: Kinoshita
mesh_terms: D000368:Aged; D002531:Cerebellum / Q000098:blood supply* / Q000000981:diagnostic imaging* / Q000473:pathology; D002540:Cerebral Cortex / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology*; D002560:Cerebrovascular Circulation; D020803:Encephalitis, Herpes Simplex / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*