title: Effect of a calcium carbonate-based dentifrice on in situ enamel remineralization.
abstract: This crossover study evaluated the effect of calcium carbonate (CaCO(3))-based monofluorophosphate dentifrice on enamel remineralization. Ten volunteers wore palatal appliances containing four enamel blocks with caries-like lesions, two of them covered by a test plaque of mutans streptococci. The following treatments were evaluated: a negative control, a silica-based or a CaCO(3)-based dentifrice, and the percentage of enamel surface microhardness recovery was determined. The CaCO(3)-based dentifrice was more effective than the negative control on the enhancement of enamel remineralization, either in the presence or absence of test plaque. This efficacy was also shown by the silica-based dentifrice but only in the presence of test plaque.
authors.affiliation: Faculty of Dentistry of Piracicaba, State University of Campinas, Av. Limeira 901, 13414-903 Piracicaba, SP, Brazil. jcury@fop.unicamp.br
authors.forename: J A
authors.initials: JA
authors.lastname: Cury
authors.forename: G S
authors.initials: GS
authors.lastname: Simões
authors.forename: A A
authors.initials: AA
authors.lastname: Del Bel Cury
authors.forename: N C
authors.initials: NC
authors.lastname: Gonçalves
authors.forename: C P M
authors.initials: CP
authors.lastname: Tabchoury
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D001697:Biomedical and Dental Materials / Q000627:therapeutic use; D002119:Calcium Carbonate / Q000627:therapeutic use*; D002327:Cariostatic Agents / Q000627:therapeutic use*; D002417:Cattle; D018592:Cross-Over Studies; D003731:Dental Caries / Q000188:drug therapy / Q000382:microbiology; D003743:Dental Enamel / Q000737:chemistry / Q000187:drug effects*; D003802:Dentifrices / Q000737:chemistry / Q000627:therapeutic use*; D005459:Fluorides / Q000627:therapeutic use; D006244:Hardness / Q000187:drug effects; D006801:Humans; D009930:Organic Chemicals; D010710:Phosphates / Q000627:therapeutic use; D014089:Tooth Remineralization
chemical_list: D001697:Biomedical and Dental Materials; D002327:Cariostatic Agents; D003802:Dentifrices; D009930:Organic Chemicals; D010710:Phosphates; C480094:sorriso; C012980:fluorophosphate; D002119:Calcium Carbonate; D005459:Fluorides