title: Cytotoxic allyl retrochalcone from the roots of Glycyrrhiza inflata.
abstract: Two known retrochalcones, licochalcone A (1) and licochalcone C (2), and one new retrochalcone, licochalcone E (4) were isolated by cytotoxicity-guided fractionation from the roots of Glycyrrhiza inflata along with an ordinary chalcone, isoliquiritigenin (3). The structure of the new retrochalcone was elucidated through a spectroscopic analysis.
authors.affiliation: College of Pharmacy & Drug Development Research Institute, Chonnam National University, Gwangju 501-757, Korea.
authors.forename: Goo
authors.initials: G
authors.lastname: Yoon
authors.forename: Young Do
authors.initials: YD
authors.lastname: Jung
authors.forename: Seung Hoon
authors.initials: SH
authors.lastname: Cheon
mesh_terms: D045744:Cell Line, Tumor; D047188:Chalcones / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity*; D003603:Cytotoxins / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity*; D006035:Glycyrrhiza / Q000633:toxicity*; D006801:Humans; D018517:Plant Roots
chemical_list: D047188:Chalcones; D003603:Cytotoxins