Motor unit action potential topography and its use in motor unit number estimation.
High-density multichannel electromyography (EMG) recordings add spatial information to the temporal information content of the surface EMG (sEMG) signal. This study explores the potential value of such multichannel information at a single motor unit level, in particular for the improvement of motor unit number estimation (MUNE) techniques. It is shown that multichannel recordings make it easier to distinguish motor unit action potentials (MUAPs) and that MUAP combinations can be better resolved. Furthermore, the spatiotemporal information allows a quantitative assessment of the representativity of the mean of the recorded MUAPs in relation to the maximum CMAP, i.e., for the muscle as a whole. In general, this is practically impossible on the basis of temporal information alone. For these reasons, we expect that high-density sEMG has the potential to address several methodological limitations of single channel surface EMG recordings. This is specifically illustrated in this study for one of the MUNE techniques in use, the F-response method.
Blok
Joleen H
JH
Department of Clinical Neurophysiology, Erasmus Medical Centre, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands. j.h.blok@erasmusmc.nl
Van Dijk
Johannes P
JP
Zwarts
Machiel J
MJ
Stegeman
Dick F
DF
D000200:Action Potentials / Q000502:physiology*; D000328:Adult; D002452:Cell Count / Q000379:methods; D004558:Electric Stimulation / Q000295:instrumentation / Q000379:methods; D004576:Electromyography / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology*; D009119:Muscle Contraction / Q000502:physiology; D018485:Muscle Fibers, Skeletal / Q000502:physiology*; D018482:Muscle, Skeletal / Q000294:innervation / Q000502:physiology*; D009469:Neuromuscular Junction / Q000033:anatomy & histology / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation