title: Progressive multifocal leukoencephalopathy (PML) presenting as intractable dystonia in an HIV-infected child.
abstract: Progressive multifocal leukoencephalopathy (PML) has been described in adult immunocompromised patients and has a progressive downhill course. Though dementia and motor disturbances have been described, intractable dystonia is a very unusual manifestation. In children, PML is very rare and often misdiagnosed as other central nervous system (CNS) encephalopathy. No definitive treatment is available.
authors.affiliation: Department of Pediatric HIV, BJ Wadia Hospital for Children, Mumbai, India. irashah@pediatriconcall.com
authors.forename: Ira
authors.initials: I
authors.lastname: Shah
authors.forename: Priya
authors.initials: P
authors.lastname: Chudgar
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D002648:Child; D003937:Diagnosis, Differential; D020821:Dystonic Disorders / Q000209:etiology* / Q000473:pathology; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000150:complications* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D011859:Radiography; D012640:Seizures / Q000209:etiology