Immunomodulatory activity of cucurbitacin E isolated from Ecballium elaterium.
The immunomodulatory effect of cucurbitacin E, extracted from Ecballium elaterium, was tested on peripheral human lymphocytes. These lymphocytes were co-cultured with cancer cells and an interesting lymphocyte-mediated cytotoxicity was observed.
Attard
E
E
Institute of Agriculture, University of Malta, Malta. everaldo.attard@um.edu.mt
Brincat
M P
MP
Cuschieri
A
A
D045744:Cell Line, Tumor; D019662:Cucurbitaceae; D005260:Female; D006801:Humans; D007155:Immunologic Factors / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008214:Lymphocytes / Q000187:drug effects*; D008297:Male; D008517:Phytotherapy; D014315:Triterpenes / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
D007155:Immunologic Factors; D014315:Triterpenes; C102326:cucurbitacin E