TRP channels in mechanosensation.
Channels of the TRP superfamily have sensory roles in a wide variety of receptor cells, especially in mechanosensation. In some cases, the channels appear to be directly activated by mechanical force; in others, they appear to be downstream of a messenger pathway initiated by force on a non-channel sensor. A remaining challenge for most of these mechanosensory TRPs is to clarify the specific mechanism of activation.
Lin
Shuh-Yow
SY
Howard Hughes Medical Institute and Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115, USA.
Corey
David P
DP
D000818:Animals; D015220:Calcium Channels / Q000737:chemistry / Q000502:physiology*; D006801:Humans; D008465:Mechanoreceptors / Q000737:chemistry / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D050052:TRPC Cation Channels
D015220:Calcium Channels; D050052:TRPC Cation Channels