Uncertainty analysis of a dynamic vapor sorption-fast gas chromatography-flame ionization detection method for the rapid analysis of volatile release from glassy matrices.
Uncertainty analysis was conducted with a dynamic vapor sorption-fast gas chromatography-flame ionization detection (DVS-fast GC-FID) method, developed to rapidly analyze the extent of volatile release that occurs from carbohydrate glasses due to humidification and temperature increases. Triplicate samples progressed through a two-step special automatic operation method in the DVS. Samples were exposed to relative humidities ranging from 40 to 90% (in 10% increments) at 15, 25, and 35 degrees C. Uncertainty analysis shows that the DVS-fast GC-FID method uncertainty is smaller than the natural sample uncertainty, indicating that the variability in a sample's physical properties has a dominant impact on the overall uncertainty of the volatile retention results obtained using the DVS-fast GC-FID method. Uncertainty analysis also indicates that the variance associated with the mass of benzaldehyde measured by the DVS-fast GC-FID is the largest contributor to the overall benzaldehyde retention variance when the cumulative mass of benzaldehyde measured is small.
Bohn
Dawn M
DM
Diageo Global Supply, 903 West 143rd Street, Plainfield, Illinois 60544, USA.
Schmidt
Arthur R
AR
Schmidt
Shelly J
SJ
D000327:Adsorption; D001547:Benzaldehydes / Q000032:analysis / Q000737:chemistry*; D002849:Chromatography, Gas / Q000379:methods*; D006813:Humidity; D007700:Kinetics; D008433:Mathematics; D008956:Models, Chemical; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013696:Temperature; D035501:Uncertainty; D014835:Volatilization
D001547:Benzaldehydes; C032175:benzaldehyde