Unusual solitary fibrous tumors in the central nervous system: a report of two cases.
Solitary fibrous tumors (SFTs) are uncommon, and most are found in the pleura. Extrapleural SFTs are rare and have been found in the lung, pericardium, mediastinum, soft tissue of any site, and upper respiratory tract. SFTs of the central nervous system (CNS) are very rare. The biologic features are unknown and remain poorly understood from a clinical standpoint. Most neurosurgeons do not believe that SFTs can present as primary CNS neoplasms. Most SFTs are clinically benign and indolent, and recurrences after surgical excision are scarce. Because malignant transformation or metastasis has been reported, all SFTs should be treated as having malignant potential. Long-term follow-up is recommended. We report two cases, so that surgeons may recognize that this is an entity different from other spindle-cell CNS tumors.
Hu
Shih-Wen
SW
Department of Pathology, Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan.
Tsai
Kun-Bow
KB
Yang
Sheau-Fang
SF
Lee
Kung-Shing
KS
Chai
Chee-Yin
CY
D000328:Adult; D018952:Antigens, CD34 / Q000032:analysis; D016543:Central Nervous System Neoplasms / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018218:Neoplasms, Fibrous Tissue / Q000175:diagnosis / Q000473:pathology*; D014057:Tomography, X-Ray Computed
D018952:Antigens, CD34