In vitro activities of amphotericin B and voriconazole against aleurioconidia from Aspergillus terreus.
This study used aleurioconidia as inoculum and compared the MICs of amphotericin B and voriconazole to those obtained for conidia of 31 Aspergillus terreus strains. For conidia and aleurioconidia, the MIC at which 90% of strains were inhibited was 2.5 microg/ml and 5 microg/ml with amphotericin B and 1 microg/ml and 2 microg/ml with voriconazole.
Lass-Flörl
Cornelia
C
Department of Hygiene, Microbiology and Social Medicine, Medical University Innsbruck, Fritz Pregl Str. 3/III, Innsbruck 6020, Austria. Cornelia.Lass-Floerl@uibk.ac.at
Rief
Alexandra
A
Leitner
Sandra
S
Speth
Cornelia
C
Würzner
Reinhard
R
Dierich
Manfred P
MP
D000666:Amphotericin B / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D001230:Aspergillus / Q000187:drug effects / Q000254:growth & development*; D006801:Humans; D025301:Hyphae / Q000187:drug effects / Q000254:growth & development; D008826:Microbial Sensitivity Tests; D011743:Pyrimidines / Q000494:pharmacology*; D014230:Triazoles / Q000494:pharmacology*; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D000666:Amphotericin B; D065819:Voriconazole