title: Primary non-gestational choriocarcinoma of the uterine cervix: a case report.
abstract: BACKGROUND
  Primary non-gestational choriocarcinoma of the female genital tract has been described in the ovaries and is very unusual in other genital sites.
  
  
  METHODS
  Primary non-gestational uterine cervical choriocarcinoma was diagnosed in a patient, 32, single, without previous sexual contact nor antecedent pregnancy, admitted to the hospital with irregular vaginal hemorrhaging. Pelvic examination realized under anesthetic revealed a tumor mass occupying the uterine cervix. Metastases investigation was realized and the patient was accepted as FIGO IV: risk factor of 13. She was submitted to intensive chemotherapy and hysterectomy, showing general recovery, but died from drug-resistant disease 12 months later. Histological, immunohistochemical, and molecular genetics studies confirmed non-gestational choriocarcinoma.
  
  
  CONCLUSIONS
  Primary non-gestational uterine cervical choriocarcinoma may arise from germ cell tumor or epithelial tissue.
authors.affiliation: Department of Gynecology and Obstetrics, UNESP-São Paulo State University, Botucatu/SP, Brazil. imaesta@fmb.unesp.br
authors.forename: Izildinha
authors.initials: I
authors.lastname: Maestá
authors.forename: Odair Carlito
authors.initials: OC
authors.lastname: Michelin
authors.forename: Paulo
authors.initials: P
authors.lastname: Traiman
authors.forename: Paula
authors.initials: P
authors.lastname: Hokama
authors.forename: Marilza Vieira Cunha
authors.initials: MV
authors.lastname: Rudge
mesh_terms: D000328:Adult; D031954:Choriocarcinoma, Non-gestational / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000628:therapy