title: Total synthesis of peroxyacarnoates A and D: metal-mediated couplings as a convergent approach to polyunsaturated peroxides.
abstract: [reaction: see text] The first syntheses of peroxyacarnoates A and D, members of a family of enyne-containing alkoxydioxanes, have been achieved on the basis of chemoselective ozonolysis within a polyunsaturated framework and Pd-mediated cross-couplings of a functionalized 1,2-dioxane.
authors.affiliation: Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588-0304, USA.
authors.forename: Chunping
authors.initials: C
authors.lastname: Xu
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Raible
authors.forename: Patrick H
authors.initials: PH
authors.lastname: Dussault
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D000818:Animals; D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D004146:Dioxanes / Q000138:chemical synthesis* / Q000737:chemistry; D007202:Indicators and Reagents; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry; D011161:Porifera / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D001688:Biological Products; D004146:Dioxanes; D007202:Indicators and Reagents; C508403:peroxyacarnoate A; C508404:peroxyacarnoate D; D010165:Palladium