title: A simple and efficient copper-catalyzed procedure for the hydrosilylation of hindered and functionalized ketones.
abstract: The catalytic hydrosilylation of highly hindered and functionalized ketones is described. The combination of inexpensive catalyst precursors, CuCl and NHC.HX (NHC = N-heterocyclic carbene), leads to a highly efficient reduction mediator for the preparation of silyl ethers from unfunctionalized and functionalized alkyl, cyclic, bicyclic, aromatic, and heteroaromatic ketones. A series of catalyst precursors have been structurally characterized and a catalyst-structure activity relationship is discussed.
authors.affiliation: Department of Chemistry, University of New Orleans, New Orleans, Louisiana 70148, USA.
authors.forename: Silvia
authors.initials: S
authors.lastname: Díez-González
authors.forename: Harneet
authors.initials: H
authors.lastname: Kaur
authors.forename: Fabiano Kauer
authors.initials: FK
authors.lastname: Zinn
authors.forename: Edwin D
authors.initials: ED
authors.lastname: Stevens
authors.forename: Steven P
authors.initials: SP
authors.lastname: Nolan