Catalytic asymmetric cyclopropanation at a chiral platform.
Novel chiral Robson-type macrocyclic complexes M(2)-L [where M = Mn(II), Mn(III), Co(II) and Co(III) and L denotes tetra-Schiff base chiral ligands, L1 or L2] have been synthesized by metal template condensation of 2,6-diformyl-4-methyl-phenol, with 1R,2R-diaminocyclohexane (L1) or 1R,2R-diphenylethylenediamine (L2). The dinuclear Co(II) and Co(III) complexes catalyze asymmetric cyclopropanation of styrene with diazoacetate cooperatively and with high enantioselectivity.
Gao
Jian
J
Department of Radiology, University of Texas Health Science Center-San Antonio, Texas 78229-3900, USA. gao2@uthscsa.edu
Woolley
F Ross
FR
Zingaro
Ralph A
RA
D002384:Catalysis; D003500:Cyclization; D008958:Models, Molecular; D011407:Propane / Q000737:chemistry*; D013237:Stereoisomerism
D011407:Propane