[Study on the clinical epidemiology of systemic lupus erythematosus among 1433 cases].
OBJECTIVE
To explore factors that affecting the outcome of systemic lupus erythematosus (SLE) therapy.


METHODS
Factors on the results of therapy were analysed through a case-control study.


RESULTS
The common symptoms of SLE were fever, joint pain and skin eruption on face while the common provocation factors of SLE were infection and birth. Through multivariate logistic regression analyses, factors that influencing SLE result of treatment were tachycardia, diastolic pressure step-up, complement C(3) reduction, anti-ds-DNA antibody, SLE relapse and brain syndrome with the OR values as 2.28, 2.34, 2.42, 2.47, 1.98 and 5.56, respectively.


CONCLUSIONS
The symptom and clinical characteristics of SLE were complicated. SLE treatment result could be influenced by tachycardia, diastolic pressure step-up, complement C(3) reduction, anti-ds-DNA antibody, SLE relapse and brain syndrome suggesting that the prognosis of SLE patients should be comprehensively considered.
Zhang
Yong-qing
YQ
Department of Epidemiology, School of Public Health, Anhui Medical University, Hefei 230032, China.
Ye
Dong-qing
DQ
Li
Xiang-pei
XP
Zhang
Guo-qing
GQ
Fang
Yi-rong
YR
Yin
Jing
J
Yang
Shi-gui
SG
Hu
Yi-song
YS
D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002648:Child; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000453:epidemiology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012044:Regression Analysis