title: HalX: an open-source LIMS (Laboratory Information Management System) for small- to large-scale laboratories.
abstract: Structural genomics aims at the establishment of a universal protein-fold dictionary through systematic structure determination either by NMR or X-ray crystallography. In order to catch up with the explosive amount of protein sequence data, the structural biology laboratories are spurred to increase the speed of the structure-determination process. To achieve this goal, high-throughput robotic approaches are increasingly used in all the steps leading from cloning to data collection and even structure interpretation is becoming more and more automatic. The progress made in these areas has begun to have a significant impact on the more 'classical' structural biology laboratories, dramatically increasing the number of individual experiments. This automation creates the need for efficient data management. Here, a new piece of software, HalX, designed as an 'electronic lab book' that aims at (i) storage and (ii) easy access and use of all experimental data is presented. This should lead to much improved management and tracking of structural genomics experimental data.
authors.affiliation: Israel Structural Proteomics Center, Weizmann Institute of Science, Rehovot 76100, Israel.
authors.forename: Jaime
authors.initials: J
authors.lastname: Prilusky
authors.forename: Eric
authors.initials: E
authors.lastname: Oueillet
authors.forename: Nathalie
authors.initials: N
authors.lastname: Ulryck
authors.forename: Anne
authors.initials: A
authors.lastname: Pajon
authors.forename: Julie
authors.initials: J
authors.lastname: Bernauer
authors.forename: Isabelle
authors.initials: I
authors.lastname: Krimm
authors.forename: Sophie
authors.initials: S
authors.lastname: Quevillon-Cheruel
authors.forename: Nicolas
authors.initials: N
authors.lastname: Leulliot
authors.forename: Marc
authors.initials: M
authors.lastname: Graille
authors.forename: Dominique
authors.initials: D
authors.lastname: Liger
authors.forename: Lionel
authors.initials: L
authors.lastname: Trésaugues
authors.forename: Joel L
authors.initials: JL
authors.lastname: Sussman
authors.forename: Joël
authors.initials: J
authors.lastname: Janin
authors.forename: Herman
authors.initials: H
authors.lastname: van Tilbeurgh
authors.forename: Anne
authors.initials: A
authors.lastname: Poupon
mesh_terms: D018360:Crystallography, X-Ray / Q000379:methods; D030562:Databases, Protein; D012984:Software