Assessment of neurolymphomatosis by brachial plexus biopsy and PET/CT. Report of a case.
OBJECTIVE
To report a biopsy-proven neurolymphomatosis in a young woman with previous non-Hodgkin's lymphoma (NHL) of uterine cervix.


METHODS
The patient presented with a painful brachial plexopathy and developed multiple cranial and spinal nerve palsies.


RESULTS
The diagnosis was achieved by an open brachial plexus biopsy. A PET/CT study was used to assess the full extent of the disease and showed involvement of additional cranial nerves and spinal nerve roots. A complete although short lasting clinical and radiological response was achieved by means of systemic high dose methotrexate treatment combined with rituximab and intra-CSF injections of cytarabine.
Bokstein
Felix
F
Neuro-Oncology Service, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel. fbok@netvision.net.il
Goor
Odelyia
O
Shihman
Boris
B
Rochkind
Shimon
S
Even-Sapir
Einat
E
Metser
Ur
U
Neufeld
Miri
M
D000328:Adult; D001706:Biopsy; D001917:Brachial Plexus / Q000473:pathology*; D003391:Cranial Nerves / Q000473:pathology; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000175:diagnosis* / Q000473:pathology*; D010243:Paralysis / Q000209:etiology; D049268:Positron-Emission Tomography; D013126:Spinal Nerve Roots / Q000473:pathology; D014057:Tomography, X-Ray Computed; D002583:Uterine Cervical Neoplasms / Q000473:pathology*