title: A new origin for chartreusin.
abstract: Unraveling the sequence of reactions that transforms aromatic polyketide backbones into much more elaborate structures, for example the chartreusin bislactone, is challenging, but in this issue of Chemistry & Biology, Xu and coworkers [1] show that sequencing the gene clusters can provide valuable clues.
authors.affiliation: Department of Biochemistry, University of Cambridge, United Kingdom.
authors.forename: Kira
authors.initials: K
authors.lastname: Weissman
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000096:biosynthesis*; D001578:Benzopyrans; D006027:Glycosides / Q000096:biosynthesis; D007783:Lactones / Q000378:metabolism; D048630:Polyketide Synthases / Q000378:metabolism*; D013302:Streptomyces / Q000378:metabolism
chemical_list: D000903:Antibiotics, Antineoplastic; D001578:Benzopyrans; D006027:Glycosides; D007783:Lactones; C069755:chartarin; D048630:Polyketide Synthases; C002185:chartreusin