title: Improving patient outcomes in an ambulatory infusion setting: decreasing infusion reactions of patients receiving paclitaxel and carboplatin.
abstract: Nurses working in the outpatient ambulatory setting treat patients with multiple infusion drug regimens. Patients can have allergic reactions to infusions ranging from very mild to life-threatening. The reaction and the subsequent treatment measures can be very disconcerting to the patients and to the visitors in the infusion area. The nursing team described in this article took a proactive approach to minimize infusion reactions in the authors' facility, thereby ensuring the safety of other patients. Staff members examined the performance improvement data, conducted a retrospective study, and collaborated with the primary physician providers to develop rechallenge protocols for patients receiving paclitaxel and carboplatin regimens.
authors.affiliation: York Cancer Center-WellSpan Health, York, Pa, USA. RHuddleston@Wellspan.org
authors.forename: Roseann
authors.initials: R
authors.lastname: Huddleston
authors.forename: Carol
authors.initials: C
authors.lastname: Berkheimer
authors.forename: Sandra
authors.initials: S
authors.lastname: Landis
authors.forename: Dereen
authors.initials: D
authors.lastname: Houck
authors.forename: Ann
authors.initials: A
authors.lastname: Proctor
authors.forename: Joan
authors.initials: J
authors.lastname: Whiteford
mesh_terms: D000553:Ambulatory Care / Q000592:standards*; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects; D016190:Carboplatin / Q000008:administration & dosage / Q000009:adverse effects; D002985:Clinical Protocols / Q000592:standards; D003211:Concurrent Review; D004342:Drug Hypersensitivity / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D007262:Infusions, Intravenous / Q000009:adverse effects / Q000451:nursing / Q000592:standards; D020380:Needs Assessment; D009731:Nursing Audit; D015403:Nursing Evaluation Research; D017239:Paclitaxel / Q000008:administration & dosage / Q000009:adverse effects; D010414:Pennsylvania; D011292:Premedication / Q000379:methods / Q000451:nursing / Q000592:standards; D012189:Retrospective Studies; D017751:Safety Management / Q000458:organization & administration; D017749:Total Quality Management / Q000458:organization & administration*
chemical_list: D000970:Antineoplastic Agents; D016190:Carboplatin; D017239:Paclitaxel