title: Detection of qnr in clinical isolates of Escherichia coli from Korea.
abstract: qnr was detected in 2 of 260 Escherichia coli clinical isolates collected from a Korean hospital during the period 2001 to 2003. The two strains were not clonally related. qnr was located in In4 family class 1 integrons of original structure, downstream of orf513 and upstream from another resistance gene (dfrA3b) and a gene of unknown function (orf105). Transfer of the qnr determinant by conjugation could be detected from only one strain.
authors.affiliation: Division of Infectious Diseases, Asan Medical Center and Asan Institute for Life Sciences, University of Ulsan College of Medicine, 388-1 Pungnap-dong, Songpa-gu, Seoul 138-736, Korea.
authors.forename: Jin-Yong
authors.initials: JY
authors.lastname: Jeong
authors.forename: Hyun Jung
authors.initials: HJ
authors.lastname: Yoon
authors.forename: Eun Sil
authors.initials: ES
authors.lastname: Kim
authors.forename: Yoola
authors.initials: Y
authors.lastname: Lee
authors.forename: Sang-Ho
authors.initials: SH
authors.lastname: Choi
authors.forename: Nam Joong
authors.initials: NJ
authors.lastname: Kim
authors.forename: Jun Hee
authors.initials: JH
authors.lastname: Woo
authors.forename: Yang Soo
authors.initials: YS
authors.lastname: Kim
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000382:microbiology*; D029968:Escherichia coli Proteins / Q000235:genetics*; D006801:Humans; D032023:Integrons / Q000235:genetics; D007723:Korea; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D015363:Quinolones / Q000494:pharmacology; D017422:Sequence Analysis, DNA
chemical_list: D000890:Anti-Infective Agents; D029968:Escherichia coli Proteins; C485384:Qnr protein, E coli; D015363:Quinolones