title: Risk factors for failure of transvaginal sacrospinous uterine suspension in the treatment of uterovaginal prolapse.
abstract: OBJECTIVE
  The purpose of this study was to elucidate the risk factors for failure of transvaginal sacrospinous uterine suspension (SSUS) in the treatment of uterine prolapse and to examine methods for controlling these risk factors.
  
  
  METHODS
  Sixty patients with second degree uterine prolapse or greater were included in this 2-stage study, with 33 in the risk factor assessment and 27 in the clinical study of a modified treatment to eliminate identified risk factors. Patients were followed for at least 5 years. The first part of the study evaluated the risk factors for operative failure and the efficacy of the operative procedure. The second part of the study evaluated a modified treatment plan to eliminate risk factors identified in the first part of the study.
  
  
  RESULTS
  The failure rate for those with an elongated cervix (3 of 4, 75%) and those with third degree uterine prolapse (3 of 4, 75%) was significantly higher than for patients without either of these risk factors (6.9%, 2/29) [p = 0.007]. Concomitant partial trachelectomy for those with elongated cervix significantly reduced the failure rate from 75% to 0% (0/7) [p = 0.024]. In the risk factor study, SSUS was successful in 84.8% (28/33) of patients. In the clinical study of modified therapy to prevent significant risk factors, the success rate was 96.3% (26/27).
  
  
  CONCLUSIONS
  This study found that an elongated cervix and third degree uterine prolapse were the 2 main risk factors for recurrent uterine prolapse after SSUS. Concomitant partial trachelectomy as an adjuvant treatment of SSUS for treatment of uterovaginal prolapse in patients with an elongated cervix significantly reduces the rate of failure in these patients.
authors.affiliation: Urodynamic Unit, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, and Mackay Medicine, Nursing and Management College, Taipei, Taiwan.
authors.forename: Tzu-Yin
authors.initials: TY
authors.lastname: Lin
authors.forename: Tsung-Hsien
authors.initials: TH
authors.lastname: Su
authors.forename: Yeou-Lih
authors.initials: YL
authors.lastname: Wang
authors.forename: Mei-Yu
authors.initials: MY
authors.lastname: Lee
authors.forename: Ching-Hung
authors.initials: CH
authors.lastname: Hsieh
authors.forename: Kuo-Gon
authors.initials: KG
authors.lastname: Wang
authors.forename: Gin-Den
authors.initials: GD
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D008022:Ligaments / Q000601:surgery; D008875:Middle Aged; D012008:Recurrence; D012307:Risk Factors; D017211:Treatment Failure; D014596:Uterine Prolapse / Q000473:pathology / Q000601:surgery*; D014599:Uterus / Q000473:pathology; D014621:Vagina / Q000601:surgery