title: Drug metabolism and variability among patients in drug response.
authors.affiliation: Department of Pharmacology, Vanderbilt University, Nashville, TN 37232-6600, USA. grant.wilkinson@vanderbilt.edu
authors.forename: Grant R
authors.initials: GR
authors.lastname: Wilkinson
mesh_terms: D001189:Aryl Hydrocarbon Hydroxylases / Q000378:metabolism; D001682:Biological Availability; D065731:Cytochrome P-450 CYP2C19; D065729:Cytochrome P-450 CYP2C9; D019389:Cytochrome P-450 CYP2D6 / Q000378:metabolism*; D051544:Cytochrome P-450 CYP3A; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics / Q000378:metabolism*; D004347:Drug Interactions; D006801:Humans; D006899:Mixed Function Oxygenases / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010597:Pharmacogenetics; D008565:Membrane Proteins
chemical_list: D001189:Aryl Hydrocarbon Hydroxylases; D065731:Cytochrome P-450 CYP2C19; D065729:Cytochrome P-450 CYP2C9; D019389:Cytochrome P-450 CYP2D6; D051544:Cytochrome P-450 CYP3A; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D004364:Pharmaceutical Preparations; C450260:CYP2C9 protein, human; C045793:CYP2C19 protein, human; C104464:CYP3A protein, human; C496508:Cyp3a11 protein, mouse; D008565:Membrane Proteins