Modelling the vestibular head tilt response.
This paper attempts to verify the existence of potentially diagnostically significant periodic signals thought to exist in recordings of neural activity originating from the vestibular nerve, following a single tilt of the head. It then attempts to find the physiological basis of this signal, in particular focusing on the mechanical response of the vestibular system. Simple mechanical models of the semi circular canals having angular velocities applied to them were looked at. A simple single canal model was simulated using CFX software. Finally, a simple model of all three canals with elastic duct walls and a moving cupula was constructed. Pressure waves within the canals were simulated using water hammer or pressure transient theory. In particular, it was investigated whether pressure waves within the utricle following a square pulse angular velocity applied to the canal(s) may be responsible for quasi-periodic oscillatory signals. The simulations showed that there are no pressure waves resonating within the canals following a square pulse angular velocity applied to the canal(s). The results show that the oscillatory signals are most likely not mechanical in origin. It was concluded that further investigation is required.
Heibert
D
D
Department of Electrical and Computer Systems Engineering, Monash University, Clayton, Australia.
Lithgow
B
B
D001300:Audiometry, Evoked Response / Q000379:methods; D003198:Computer Simulation; D018069:Hair Cells, Vestibular / Q000502:physiology; D019416:Head Movements / Q000502:physiology*; D018475:Head-Down Tilt / Q000502:physiology*; D006801:Humans; D040542:Mechanotransduction, Cellular / Q000502:physiology*; D044085:Microfluidics / Q000379:methods; D008954:Models, Biological; D010812:Physical Stimulation / Q000379:methods; D011187:Posture / Q000502:physiology*; D011312:Pressure; D012027:Reflex, Vestibulo-Ocular / Q000502:physiology*; D014722:Vestibule, Labyrinth / Q000294:innervation / Q000502:physiology*