title: Extradural spinal cavernous angiomas: report of seven cases.
abstract: The authors describe seven cases of extradural spinal cavernous angioma. Although cavernoma itself is not rare, the extradural spinal localization is uncommon and makes preoperative differential diagnosis difficult. Routine MRI investigation has aided neurosurgeons in evaluating the true incidence of these vascular malformations, which was understimated in the past. The data published so far have not entirely clarified the treatment of choice for these lesions. Considering their rarity in this site, their presenting symptoms and the difficulties involved in neuroradiological diagnosis, the authors discuss the role of surgery as the principal form of treatment and review the relevant literature. Seven patients (4 male, 3 female) were admitted to our Institute of Neurosurgery between 1992 and 2004, with a 5-6 month history (range=2-365 days) of low back pain or radicular pain, sometimes associated with paresthesia. All patients had a CT scan, as well as MRI with gadolinium when possible, which detected an extradural roundish lesion: differential diagnosis was very difficult, especially between neurinoma and cavernoma. Treatment was always surgical and resection of the lesion radical. Postoperatively, all patients presented complete regression of clinical symptoms. In all cases histological diagnosis was cavernous angioma. Postoperative MRI with gadolinium or CT scan with IV contrast, performed before discharge, confirmed radical removal of the vascular malformation in all cases. Our experience confirms that surgery should be the treatment of choice for these lesions, in view of both their tendency to bleed and their straightforward surgical removal.
authors.affiliation: Department of Neurosurgical Sciences, Neurosurgery, University of Rome, La Sapienza, Rome, Italy. santorant@libero.it
authors.forename: Antonio
authors.initials: A
authors.lastname: Santoro
authors.forename: Manolo
authors.initials: M
authors.lastname: Piccirilli
authors.forename: Roberto
authors.initials: R
authors.lastname: Bristot
authors.forename: Valerio
authors.initials: V
authors.lastname: di Norcia
authors.forename: Maurizio
authors.initials: M
authors.lastname: Salvati
authors.forename: Roberto
authors.initials: R
authors.lastname: Delfini
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004388:Dura Mater / Q000473:pathology; D005260:Female; D006392:Hemangioma, Cavernous / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007796:Laminectomy; D017116:Low Back Pain / Q000209:etiology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D010146:Pain / Q000209:etiology; D013125:Spinal Neoplasms / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed