[Tumor markers of childhood cancer].
Tumor markers are the substances which are produced from malignant cells and are detectable from peripheral blood or body fluid. These markers are used for the evaluation of treatment effectiveness or the detection of relapse. In most cases of pediatric cancer, specific molecular abnormalities of tumor cells have been able to be identified. Evaluation of these molecular markers is critical for the diagnosis and the choice of treatment. Recently, these molecular markers have also come to be used for the detection of minimal residual disease. Such a system can be regarded as a kind of tumor marker.
Shioda
Yoko
Y
Division of Pediatric Oncology, National Center for Child Health and Development, Tokyo, Japan.
Kumagai
Masa-aki
MA
D014408:Biomarkers, Tumor / Q000097:blood*; D001932:Brain Neoplasms / Q000175:diagnosis; D002648:Child; D006063:Chorionic Gonadotropin / Q000097:blood; D018237:Germinoma / Q000175:diagnosis; D006719:Homovanillic Acid / Q000097:blood; D006801:Humans; D007938:Leukemia / Q000175:diagnosis / Q000235:genetics; D008113:Liver Neoplasms / Q000175:diagnosis; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000235:genetics; D009369:Neoplasms / Q000175:diagnosis*; D010751:Phosphopyruvate Hydratase / Q000097:blood; D016315:Proto-Oncogene Proteins c-abl / Q000097:blood; D019572:Retinal Neoplasms / Q000175:diagnosis; D012175:Retinoblastoma / Q000175:diagnosis; D014565:Urogenital Neoplasms / Q000175:diagnosis; D000509:alpha-Fetoproteins / Q000032:analysis
D014408:Biomarkers, Tumor; D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins; D016315:Proto-Oncogene Proteins c-abl; D010751:Phosphopyruvate Hydratase; D006719:Homovanillic Acid