title: [Pneumococcal meningitis in France: age and medical risk factors in children].
abstract: Streptococcus pneumoniae (Sp) is an important cause of morbidity and mortality among paediatric infectious diseases. The aim of this study is to analyse specific data on Sp meningitis out of the Bacterial Meningitis (BM) French Surveillance Network about mean age of BM cases and clinical features. Overall 367 Sp BM were reported between January 2001 to January 2004 (sex ratio M/F: 1.3), 69.7% were < 2 years old, median age 0.8 year (minmax 0-16.8 years). Before two years old children, 94.1% had no medical risk factor and no underlying conditions: on the other hand, after two years old, these factors were reported in 27% cases (P < 0.001). Mortality rate was 10.9%. On account of a Sp BM's pic at five months, data of the BM French Surveillance Network confirm the necessity of an early vaccination. The vaccine administration at two, three, four months with a booster during the second year, recommended in the vaccinal french calendar, seems particularly adapted to the Sp BM in France.
authors.affiliation: Groupe de pathologie infectieuse pédiatrique (GPIP) de la Société française de pédiatrie (SFP), service de microbiologie, hôpital Robert-Debré, Paris, France. edouard.bingen@rdb.ap-hop-paris.fr
authors.forename: E
authors.initials: E
authors.lastname: Bingen
authors.forename: C
authors.initials: C
authors.lastname: Lévy
authors.forename: F
authors.initials: F
authors.lastname: De la Rocque
authors.forename: M
authors.initials: M
authors.lastname: Boucherat
authors.forename: Y
authors.initials: Y
authors.lastname: Aujard
authors.forename: R
authors.initials: R
authors.lastname: Cohen
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008586:Meningitis, Pneumococcal / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control; D022242:Pneumococcal Vaccines / Q000008:administration & dosage; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate
chemical_list: D022242:Pneumococcal Vaccines