title: Smoking initiation and schizophrenia: a replication study in a Spanish sample.
abstract: In a prior US study, schizophrenia vulnerability was associated with higher risk of initiating daily smoking after 20 years of age. A survival analysis of onset age of daily smoking compared 290 controls with 250 consecutive DSM-IV schizophrenia patients from outpatient facilities at an urban catchment area in Spain. After controlling for gender and education, the cumulative hazard curves for smoking initiation age of controls and schizophrenia patients were significantly different. After age 20, smoking initiation rates were higher in all schizophrenia patients (and in 107 schizophrenia patients who started daily smoking at least 5 years before illness onset).
authors.affiliation: Department of Psychiatry and Institute of Neurosciences, Universidad de Granada, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Gurpegui
authors.forename: José M
authors.initials: JM
authors.lastname: Martínez-Ortega
authors.forename: M Carmen
authors.initials: MC
authors.lastname: Aguilar
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Diaz
authors.forename: Hernando M
authors.initials: HM
authors.lastname: Quintana
authors.forename: Jose
authors.initials: J
authors.lastname: de Leon
mesh_terms: D000328:Adult; D000553:Ambulatory Care / Q000706:statistics & numerical data; D003155:Community Mental Health Centers / Q000706:statistics & numerical data; D005260:Female; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D011336:Probability; D016016:Proportional Hazards Models; D015203:Reproducibility of Results; D012559:Schizophrenia / Q000175:diagnosis / Q000453:epidemiology*; D012907:Smoking / Q000453:epidemiology*; D013030:Spain / Q000453:epidemiology; D013223:Statistics as Topic; D016019:Survival Analysis; D014505:Urban Population / Q000706:statistics & numerical data