title: Myocardial protection during neonatal cardiac surgery.
abstract: Myocardial protection is of major concern in neonatal cardiac surgery where coronary ostial transfer is required as part of the surgical procedure. Retrograde coronary sinus perfusion (RCSP) of cold cardioplegic solution was evaluated in infants undergoing arterial switch operations. Hemodynamic measurements and postoperative cardiac troponin I (cTnI) levels were estimated in addition to transthoracic echocardiography to assess the extent of myocardial injury. The results were compared with a similar cohort of patients where ante grade selective coronary artery perfusion (ASCP) was used during coronary ostial transfer. Our experience suggests that RCSP is a useful option in this subset of patients.
authors.affiliation: Royal Hospital, Muscat, Oman. madan@omantel.net.com
authors.forename: Madan Mohan
authors.initials: MM
authors.lastname: Maddali
authors.forename: John
authors.initials: J
authors.lastname: Valliattu
authors.forename: Jutta
authors.initials: J
authors.lastname: Fahr
authors.forename: Taha
authors.initials: T
authors.lastname: al Delamie
authors.forename: Sunny
authors.initials: S
authors.lastname: Zacharias
mesh_terms: D002314:Cardioplegic Solutions; D002315:Cardiopulmonary Bypass / Q000379:methods; D015331:Cohort Studies; D017548:Echocardiography, Transesophageal; D005260:Female; D006324:Heart Arrest, Induced / Q000379:methods*; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn; D019157:Ischemic Preconditioning, Myocardial / Q000379:methods*; D008297:Male; D015428:Myocardial Reperfusion Injury / Q000517:prevention & control*; D011379:Prognosis; D018570:Risk Assessment; D015996:Survival Rate; D016896:Treatment Outcome
chemical_list: D002314:Cardioplegic Solutions