title: Proliferating hemangioma of infancy: successful treatment with topical 5% imiquimod cream.
abstract: A 4-month-old girl had a proliferating hemangioma of infancy (infantile hemangioma) affecting the chest wall. The lesion had appeared 1 week after birth, demonstrating both superficial and deep components, and was rapidly enlarging. It had become painful and superficially eroded. Treatment with topical 5% imiquimod cream three times a week was associated with signs of involution after 10 days, and complete resolution after 10 weeks of therapy. The treatment was well tolerated.
authors.affiliation: Department of Dermatology, Case-Western Reserve University School of Medicine, Cleveland, Ohio, USA. Paulhazen@aol.com
authors.forename: Paul G
authors.initials: PG
authors.lastname: Hazen
authors.forename: James F
authors.initials: JF
authors.lastname: Carney
authors.forename: Conley W
authors.initials: CW
authors.lastname: Engstrom
authors.forename: Karen L
authors.initials: KL
authors.lastname: Turgeon
authors.forename: Michael D
authors.initials: MD
authors.lastname: Reep
authors.forename: Arrthapol
authors.initials: A
authors.lastname: Tanphaichitr
mesh_terms: D000287:Administration, Topical; D000634:Aminoquinolines / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005260:Female; D006391:Hemangioma / Q000188:drug therapy*; D006801:Humans; D000077271:Imiquimod; D007223:Infant; D012878:Skin Neoplasms / Q000188:drug therapy*
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod