Late thrombosis of sirolimus-eluting stents following noncardiac surgery.
We describe two patients with in-stent thrombosis occurring 4 and 21 months after implantation of sirolimus-eluting stents. Both cases occurred following noncardiac surgery. In both cases, aspirin had been stopped prior to surgery. Both patient sustained a severe myocardial infarction; one died. The occurrence of late thrombosis of sirolimus-eluting stents is of concern.
Nasser
Mithal
M
Department of Cardiology, Rambam Medical Center, Technion Medical School, Haifa, Israel.
Kapeliovich
Michael
M
Markiewicz
Walter
W
D000368:Aged; D000369:Aged, 80 and over; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects; D006348:Cardiac Surgical Procedures; D020099:Coated Materials, Biocompatible / Q000627:therapeutic use*; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000628:therapy; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000628:therapy; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000209:etiology*; D020123:Sirolimus / Q000627:therapeutic use*; D015607:Stents / Q000009:adverse effects*; D013997:Time Factors
D020099:Coated Materials, Biocompatible; D010975:Platelet Aggregation Inhibitors; D020123:Sirolimus