Candida tropicalis causing prosthetic valve endocarditis.
The incidence of endocarditis produced by the so-called "opportunists" as a complication of prosthetic valve surgery is progressively increasing in frequency and gradually transforming the clinical picture habitually associated with this disease. Candida endocarditis is an unusual but severe complication caused by Candida albicans or other fungal species. This case and a review of the literature indicate that Candida endocarditis treated with amphotericin B and prosthetic valve replacement may recur months after treatment, and that late recurrent Candida endocarditis, which is difficult to diagnose and treat, may be best prevented by lifelong antifungal suppressive therapy.
Nagaraja
P A
PA
Department of Microbiology, Narayana Hrudayalaya, Bangalore, India.
Mathew
T
T
Shetty
D P
DP
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001705:Bioprosthesis / Q000009:adverse effects*; D041022:Candida tropicalis / Q000302:isolation & purification; D002177:Candidiasis / Q000188:drug therapy / Q000209:etiology*; D004696:Endocarditis / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008943:Mitral Valve / Q000601:surgery; D012196:Review Literature as Topic
D000935:Antifungal Agents; D000666:Amphotericin B