title: Full-thickness macular hole after LASIK for the correction of myopia.
abstract: OBJECTIVE
  To describe 19 patients (20 eyes) who developed a macular hole (MH) after undergoing bilateral LASIK for the correction of myopia.
  
  
  METHODS
  Noncomparative, interventional, retrospective, multicenter case series.
  
  
  METHODS
  Nineteen patients (20 eyes) who developed an MH after bilateral LASIK for the correction of myopia at 10 institutions in Venezuela, Colombia, Puerto Rico, Spain, and the United States.
  
  
  METHODS
  Chart review.
  
  
  METHODS
  Macular hole development.
  
  
  RESULTS
  The MH formed between 1 to 83 months after LASIK (mean, 12.1). In 60% of cases, the MH developed < or =6 months after LASIK, and in 30% of cases it developed > or =1 year after LASIK. Eighteen of 19 (94.7%) patients were female. Mean age was 46 years (range, 25-65). All eyes were myopic (range, -0.50 to -19.75 diopters [mean, -8.9]). Posterior vitreous detachment was not present before and was documented after LASIK in 55% of eyes. A vitrectomy closed the MH on the 14 eyes that underwent surgical management, with an improvement of final best-corrected visual acuity in 13 of 14 (92.8%) patients. Our 20 eyes with a full-thickness MH after LASIK reflect an incidence of approximately 0.02% (20/83938).
  
  
  CONCLUSIONS
  An MH may infrequently develop after LASIK for the correction of myopia. Our study shows that vitreoretinal surgery can be successful in restoring vision for most myopic eyes with an MH after LASIK. Vitreoretinal interface changes may play a role in MH formation after LASIK for the correction of myopia.
authors.affiliation: Retina and Vitreous Service, Clinica Oftalmologica Centro Caracas, Caracas, Venezuela. areval1@telcel.net.ve
authors.forename: J Fernando
authors.initials: JF
authors.lastname: Arevalo
authors.forename: Aristides J
authors.initials: AJ
authors.lastname: Mendoza
authors.forename: Wandsy
authors.initials: W
authors.lastname: Velez-Vazquez
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Rodriguez
authors.forename: Alvaro
authors.initials: A
authors.lastname: Rodriguez
authors.forename: Jose Luis
authors.initials: JL
authors.lastname: Rosales-Meneses
authors.forename: Juan B
authors.initials: JB
authors.lastname: Yepez
authors.forename: Ernesto
authors.initials: E
authors.lastname: Ramirez
authors.forename: Amr
authors.initials: A
authors.lastname: Dessouki
authors.forename: Clement K
authors.initials: CK
authors.lastname: Chan
authors.forename: Robert A
authors.initials: RA
authors.lastname: Mittra
authors.forename: Robert C
authors.initials: RC
authors.lastname: Ramsay
authors.forename: Reinaldo A
authors.initials: RA
authors.lastname: Garcia
authors.forename: José M
authors.initials: JM
authors.lastname: Ruiz-Moreno
mesh_terms: D000328:Adult; D000368:Aged; D003315:Cornea / Q000601:surgery*; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D011183:Postoperative Complications; D012167:Retinal Perforations / Q000209:etiology* / Q000601:surgery; D012189:Retrospective Studies; D012307:Risk Factors