title: Aural involvement in loxoscelism: case report and literature review.
abstract: An 11-year-old male presented with fever, rash, and a necrotic lesion on the lobule of the left ear. The lesion became tender and formed an eschar over 4 days. The patient developed leukocytosis, hemolytic anemia, and proteinuria, and was diagnosed with systemic loxoscelism from a brown recluse spider bite. He was managed with supportive therapy and improved in 4 days. Loxoscelism is a clinical diagnosis which should be suspected in an otherwise healthy patient with a necrotic wound, particulary in the endemic Southern and Midwestern United States. Physicians should be aware of this disease entity and its complications.
authors.affiliation: Department of Otolaryngology--Head and Neck Surgery, University of Tennessee Health Science Center, 956 Court Ave., Room B216, Memphis, TN 38163, USA.
authors.forename: Sreekrishna Kanth
authors.initials: SK
authors.lastname: Donepudi
authors.forename: Khwaja Asif
authors.initials: KA
authors.lastname: Ahmed
authors.forename: Rose Mary S
authors.initials: RM
authors.lastname: Stocks
authors.forename: Deborah
authors.initials: D
authors.lastname: Nelson
authors.forename: Jerome W
authors.initials: JW
authors.lastname: Thompson
mesh_terms: D000743:Anemia, Hemolytic / Q000209:etiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D004431:Ear, External / Q000473:pathology*; D017707:Erythrocyte Transfusion; D005076:Exanthema / Q000209:etiology; D005334:Fever / Q000209:etiology; D005440:Fluid Therapy; D006456:Hemoglobinuria / Q000209:etiology; D006801:Humans; D007964:Leukocytosis / Q000209:etiology; D008297:Male; D009336:Necrosis; D010727:Phosphoric Diester Hydrolases / Q000009:adverse effects*; D011507:Proteinuria / Q000209:etiology; D001098:Spider Bites / Q000175:diagnosis* / Q000628:therapy; D013111:Spider Venoms / Q000009:adverse effects*
chemical_list: D000900:Anti-Bacterial Agents; D013111:Spider Venoms; C055161:loxosceles venom; D010727:Phosphoric Diester Hydrolases