title: Primary hyperoxaluria (L-glyceric aciduria) in a cat.
abstract: A 7-month-old, male European cat was examined because of weakness and inappetence. The cat was dehydrated, polypnoeic and severely weak. Severe, generalised muscle atrophy was present. Spinal reflexes were all decreased to absent. Blood analysis and urinalysis showed several abnormalities, including intermittent hyperoxaluria. The L-gliceric acid concentration was remarkably increased. Electrodiagnostic tests of the peripheral nervous system were abnormal. At necropsy, generalised muscle atrophy was observed. Microscopically, both kidneys showed intraluminal birefringent oxalate crystals. Motor neuron degeneration and accumulation of neurofilaments were observed in the axons of the spinal motor neurons.
authors.affiliation: Clinica Veterinaria S. Marco, Via Sorio, 144/c 35141 Padua, Italy. ddeloren@tin.it
authors.forename: Davide
authors.initials: D
authors.lastname: De Lorenzi
authors.forename: Marco
authors.initials: M
authors.lastname: Bernardini
authors.forename: Marti
authors.initials: M
authors.lastname: Pumarola
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology / Q000662:veterinary; D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis*; D002415:Cats; D004576:Electromyography / Q000662:veterinary; D005260:Female; D006960:Hyperoxaluria, Primary / Q000150:complications / Q000662:veterinary*; D018908:Muscle Weakness / Q000209:etiology; D009133:Muscular Atrophy / Q000662:veterinary; D010070:Oxalates / Q000652:urine
chemical_list: D010070:Oxalates