title: Sugar derivatives containing oxiranes and alpha,beta-unsaturated gamma-lactones as potential environmentally friendly insecticides.
abstract: A range of novel sugar derivatives containing oxiranes or alpha,beta-unsaturated gamma-lactones in their structure were evaluated as potential insecticides with the added possible benefit of being benign in the environment. A number of arthropod species were chosen to represent those in the terrestrial, aerial and aquatic environments, covering target adult insects such as Musca domestica L (housefly) and Trialeurodes vaporariorum (Westwood) (glasshouse whitefly), which are public health and horticultural pests, Drosophila melanogaster Meig (fruitfly), both adult and larva, and a marine non-target crustacean, Artemia salina L. The tested compounds possessed efficacy and selectivity against these insect species, but were not toxic to brine shrimps, a reference organism in assays to evaluate the potential toxicity hazard to invertebrates in ecosystems.
authors.affiliation: Escola Superior Agrária-Instituto Politécnico de Santarém, Complexo Andaluz, Apartado 279, 2001-904 Santarém, Portugal. ips@ipsantarem.pt
authors.forename: Jorge
authors.initials: J
authors.lastname: Justino
authors.forename: Amélia P
authors.initials: AP
authors.lastname: Rauter
authors.forename: Tana
authors.initials: T
authors.lastname: Canda
authors.forename: Richard
authors.initials: R
authors.lastname: Wilkins
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Matthews
mesh_terms: D000818:Animals; D001156:Artemia / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004331:Drosophila melanogaster / Q000187:drug effects; D005027:Ethylene Oxide / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology*; D006430:Hemiptera / Q000187:drug effects; D006793:Houseflies / Q000187:drug effects; D007306:Insecticides / Q000737:chemistry / Q000494:pharmacology*; D007783:Lactones / Q000737:chemistry / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D015394:Molecular Structure
chemical_list: D007306:Insecticides; D007783:Lactones; D005027:Ethylene Oxide