Development and biological evaluation of potent and specific inhibitors of mitotic Kinesin Eg5.
Gartner
Michael
M
University of Leipzig, Institute for Organic Chemistry, Johannisallee 29, 04103 Leipzig, Germany.
Sunder-Plassmann
Nils
N
Seiler
Jeanette
J
Utz
Mathias
M
Vernos
Isabelle
I
Surrey
Thomas
T
Giannis
Athanassios
A
D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology*; D018929:Cell Culture Techniques; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology*; D006367:HeLa Cells; D006801:Humans; D016547:Kinesins / Q000037:antagonists & inhibitors*; D008938:Mitosis / Q000187:drug effects; D011743:Pyrimidines / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013871:Thiones / Q000737:chemistry* / Q000494:pharmacology
D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; C470243:KIF11 protein, human; D011743:Pyrimidines; D013871:Thiones; C400223:monastrol; D016547:Kinesins