title: Expanding the range of substrate acceptance of enzymes: combinatorial active-site saturation test.
authors.affiliation: Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470 Mülheim/Ruhr, Germany. reetz@mpi-muelheim.mpg.de
authors.forename: Manfred T
authors.initials: MT
authors.lastname: Reetz
authors.forename: Marco
authors.initials: M
authors.lastname: Bocola
authors.forename: José Daniel
authors.initials: JD
authors.lastname: Carballeira
authors.forename: Dongxing
authors.initials: D
authors.lastname: Zha
authors.forename: Andreas
authors.initials: A
authors.lastname: Vogel
mesh_terms: D001665:Binding Sites; D030562:Databases, Protein; D006868:Hydrolysis; D008049:Lipase / Q000737:chemistry* / Q000378:metabolism*; D008958:Models, Molecular; D009154:Mutation / Q000235:genetics; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D011550:Pseudomonas aeruginosa / Q000201:enzymology; D013379:Substrate Specificity
chemical_list: D008049:Lipase