title: Clinical, virologic and immunologic profiles of a young infant with severe acute respiratory syndrome.
abstract: The clinical findings, plasma viral load, cytokines and chemokines of a 4-month-old infant with severe acute respiratory syndrome (SARS) were assessed at different phases of the disease. Ribavirin failed to inhibit SARS coronavirus (SARS-CoV) replication. One-step real time reverse transcription-polymerase chain reaction for plasma SARS-CoV RNA quantification was useful for early diagnosis and monitoring viremia.
authors.affiliation: Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T.
authors.forename: Frankie W T
authors.initials: FW
authors.lastname: Cheng
authors.forename: Enders K O
authors.initials: EK
authors.lastname: Ng
authors.forename: Albert Martin
authors.initials: AM
authors.lastname: Li
authors.forename: Ellis K L
authors.initials: EK
authors.lastname: Hon
authors.forename: Rossa W K
authors.initials: RW
authors.lastname: Chiu
authors.forename: Y M Dennis
authors.initials: YM
authors.lastname: Lo
authors.forename: Pak C
authors.initials: PC
authors.lastname: Ng
mesh_terms: D016207:Cytokines / Q000097:blood*; D005260:Female; D006801:Humans; D007223:Infant; D012367:RNA, Viral / Q000097:blood; D045473:Severe acute respiratory syndrome-related coronavirus / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology; D045169:Severe Acute Respiratory Syndrome / Q000276:immunology / Q000503:physiopathology / Q000821:virology; D013997:Time Factors; D019562:Viral Load
chemical_list: D016207:Cytokines; D012367:RNA, Viral