Sino-orbital chloroma presenting as unilateral proptosis in a boy.
Granulocytic sarcoma or chloroma is an unusual localized tumor composed of cells of myeloid origin. Involvement of the orbit and the ethmoid sinuses and presenting as proptosis is rare. Diagnosis could be difficult and delayed when there are no other systemic manifestations, especially with normal peripheral blood and bone marrow picture. We present one such case with unilateral proptosis as the sole presenting sign that posed a diagnostic challenge to us. Orbital decompression by an otolaryngologist may have a role in managing such a case.
Bhat
Vikram K
VK
Department of Otolaryngology, Head and Neck Surgery, Karnataka Institute of Medical Sciences, Hubli 580021, India. entvikram@rediffmail.com
Naseeruddin
Khaja
K
Narayanaswamy
G N
GN
D015703:Antigens, CD / Q000378:metabolism; D015214:Antigens, Differentiation, Myelomonocytic / Q000378:metabolism; D002648:Child; D005005:Ethmoid Sinus / Q000473:pathology*; D005094:Exophthalmos / Q000209:etiology; D006801:Humans; D017493:Leukocyte Common Antigens / Q000378:metabolism; D008297:Male; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000201:enzymology / Q000276:immunology / Q000628:therapy; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis* / Q000201:enzymology / Q000276:immunology / Q000628:therapy; D009195:Peroxidase / Q000378:metabolism; D023981:Sarcoma, Myeloid / Q000175:diagnosis* / Q000201:enzymology / Q000276:immunology / Q000628:therapy; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D017493:Leukocyte Common Antigens; D009195:Peroxidase; C067980:CD68 antigen, human; D000097382:CD68 Molecule