title: Endobronchial pseudo-tumour caused by herpes simplex.
abstract: Herpes simplex virus (HSV) causes tracheobronchitis and pneumonitis; however, to date, there has only been one report of an endobronchial mass caused by HSV type II. This case study describes a 68-yr-old female with severe kyphoscoliosis who was intubated for acute on chronic hypercapnic respiratory failure and developed blood-tinged endotracheal secretions. Fibreoptic bronchoscopy demonstrated an endobronchial mass in the right middle lobe. Cultures grew HSV type I and biopsy specimens demonstrated cytopathological changes consistent with HSV infection. This is the first reported case of HSV type I presenting as an endobronchial tumour.
authors.affiliation: Bridgeport Hospital, Yale-New Haven Health, 267 Grant Street, Bridgeport, CT 06610-0120, USA. paupad@bpthosp.org
authors.forename: A
authors.initials: A
authors.lastname: Upadya
authors.forename: L
authors.initials: L
authors.lastname: Tilluckdharry
authors.forename: C D
authors.initials: CD
authors.lastname: Nagy
authors.forename: P
authors.initials: P
authors.lastname: Ravichandran
authors.forename: C
authors.initials: C
authors.lastname: Manthous
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000368:Aged; D001982:Bronchial Diseases / Q000175:diagnosis / Q000628:therapy / Q000821:virology*; D001999:Bronchoscopy; D017809:Fatal Outcome; D005260:Female; D006561:Herpes Simplex / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007442:Intubation, Intratracheal; D007738:Kyphosis / Q000150:complications; D016726:Plasma Cell Granuloma, Pulmonary / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012131:Respiratory Insufficiency / Q000209:etiology / Q000628:therapy; D012600:Scoliosis / Q000150:complications
chemical_list: D000212:Acyclovir