[Ion-pair solid-phase extraction (SPE) and HPLC analysis of paraquat in biological sample].
OBJECTIVE
To establish an HPLC method for the determination of Paraquat in biological samples.


METHODS
Paraquat in biological samples was extracted by C18 columns which were pre-treated with cetyl-trimethyl ammonium bromide (CTAB) and soudium dodecyl sulphate (SDS), and analysed by HPLC/DAD.


RESULTS
The detection limit of the method was 1 ng x mL(-1), and the average recoveries were 81%-94%.


CONCLUSIONS
The method can be used to analysis of paraquat in biological samples.
Wang
Rui-hua
RH
Forensic Medicine School of Kunming Medical College, Kunming 650031, China.
Su
Shao-ming
SM
Qin
Guang-ming
GM
D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D006540:Herbicides / Q000032:analysis* / Q000737:chemistry; D008099:Liver / Q000737:chemistry*; D010269:Paraquat / Q000032:analysis*; D011817:Rabbits; D012680:Sensitivity and Specificity; D012967:Sodium Dodecyl Sulfate; D012997:Solvents; D013552:Swine
D006540:Herbicides; D012997:Solvents; D012967:Sodium Dodecyl Sulfate; D010269:Paraquat