[Activity of tissue cathepsin-L-like proteinases of women with womb body oncopathology].
Activity and optimal pH of cathepsin-L-like proteinases was studied in benign and malignant tumours of the womb body. In the benign tumors activity of cathepsin-L-like proteinases changes depending on the expansion and depth of extension benign tumour and is defined by proliferative potential of tumour cells of myometrium and endometrium. Activity of cathepsin-L-like proteinases in malignant epithelial tumour of endometrium--adenocarcinoma is inversely proportional to the level of differentiation of the tumour cells.
Vovchuk
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Chernadchuk
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D000328:Adult; D000368:Aged; D000375:Aging / Q000378:metabolism / Q000473:pathology; D016022:Case-Control Studies; D056668:Cathepsin L; D002403:Cathepsins / Q000378:metabolism*; D002454:Cell Differentiation; D049109:Cell Proliferation; D003546:Cysteine Endopeptidases / Q000378:metabolism*; D004717:Endometrium / Q000201:enzymology; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000201:enzymology* / Q000473:pathology; D008875:Middle Aged; D009215:Myometrium / Q000201:enzymology; D014594:Uterine Neoplasms / Q000201:enzymology* / Q000473:pathology
D002403:Cathepsins; D003546:Cysteine Endopeptidases; C534281:CTSL protein, human; D056668:Cathepsin L