title: TIR domain-containing adaptors regulate TLR signaling pathways.
authors.affiliation: Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Shizuo
authors.initials: S
authors.lastname: Akira
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000502:physiology*; D033942:Adaptor Proteins, Vesicular Transport / Q000502:physiology; D000818:Animals; D000943:Antigens, Differentiation / Q000502:physiology; D006801:Humans; D008562:Membrane Glycoproteins / Q000502:physiology*; D051379:Mice; D053594:Myeloid Differentiation Factor 88; D011956:Receptors, Cell Surface / Q000502:physiology*; D011971:Receptors, Immunologic / Q000502:physiology; D017472:Receptors, Interleukin-1 / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*; D051193:Toll-Like Receptors
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D033942:Adaptor Proteins, Vesicular Transport; D000943:Antigens, Differentiation; C507779:MYD88 protein, human; D008562:Membrane Glycoproteins; C507780:Myd88 protein, mouse; D053594:Myeloid Differentiation Factor 88; D011956:Receptors, Cell Surface; D011971:Receptors, Immunologic; D017472:Receptors, Interleukin-1; C434984:TIRAP protein, human; C499045:TIRAP protein, mouse; D051193:Toll-Like Receptors; C074282:translocating chain-associating membrane protein (TRAM)