title: An investigation of MRSA infection in a hospice.
abstract: This study investigated the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) carriage and infection among patients admitted to a hospice. Under the existing policy at this hospice, only patients admitted from hospital wards where MRSA is known to be present are screened for MRSA prior to transfer. Hence the investigators were keen to study patients transferred from settings other than this. One hundred and twenty patients, all either from the community or from hospital wards without known MRSA, were entered into the study ('study group') and were swabbed for MRSA on admission to the hospice. Swabbing was continued at weekly intervals until discharge or death. Of the 120 patients, seven (5.8%) were MRSA positive on admission. A further four patients who were negative on admission showed MRSA on later swabs. Another two patients developed symptomatic infections during admission that were proven to be due to MRSA, but neither of these had shown MRSA on any swabs taken during the study. During the study period, a separate group of 156 patients was swabbed routinely before transfer from hospital wards where MRSA was known to be present in accordance with hospice policy ('non-study group'). Of these patients, 11 (7.1%) were found to be colonized with MRSA but none developed associated symptomatic infection. It appears that the risk of symptomatic infection with MRSA in hospice patients is low, and the burden placed on this vulnerable group by conventional eradication regimes may be disproportionate to any benefit derived.
authors.affiliation: St Christopher's Hospice, London. simone.ali1@southdowns.nhs.uk
authors.forename: Simone
authors.initials: S
authors.lastname: Ali
authors.forename: Nigel
authors.initials: N
authors.lastname: Sykes
authors.forename: Petra
authors.initials: P
authors.lastname: Flock
authors.forename: Emma
authors.initials: E
authors.lastname: Hall
authors.forename: Janet
authors.initials: J
authors.lastname: Buchan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003428:Cross Infection / Q000517:prevention & control*; D005260:Female; D006738:Hospices; D006801:Humans; D017053:Infection Control / Q000379:methods; D008297:Male; D016106:Methicillin Resistance; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000517:prevention & control*; D013211:Staphylococcus aureus