title: Use of nanobarcodes particles in bioassays.
abstract: We have developed striped metal nanoparticles, Nanobarcodes particles, which can act as encoded substrates in multiplexed assays. These particles are metallic, encodeable, machine-readable, durable, submicron-sized tags. The power of this technology is that the particles are intrinsically encoded by virtue of the difference in reflectivity of adjacent metal stripes. This chapter describes protocols for the attachment of biological molecules, and the subsequent use of the Nanobarcodes particles in bioassays.
authors.affiliation: Nanoplex Technologies Inc., Menlo Park, CA, USA.
authors.forename: R Griffith
authors.initials: RG
authors.lastname: Freeman
authors.forename: Paul A
authors.initials: PA
authors.lastname: Raju
authors.forename: Scott M
authors.initials: SM
authors.lastname: Norton
authors.forename: Ian D
authors.initials: ID
authors.lastname: Walton
authors.forename: Patrick C
authors.initials: PC
authors.lastname: Smith
authors.forename: Lin
authors.initials: L
authors.lastname: He
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Natan
authors.forename: Michael Y
authors.initials: MY
authors.lastname: Sha
authors.forename: Sharron G
authors.initials: SG
authors.lastname: Penn
mesh_terms: D000818:Animals; D020869:Gene Expression Profiling / Q000379:methods*; D006801:Humans; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D009841:Oligonucleotides / Q000737:chemistry*
chemical_list: D009841:Oligonucleotides