title: Sulfoxides in Julia-Lythgoe olefination: efficient and stereoselective preparation of di-, tri-, and tetrasubstituted olefins.
abstract: [reaction: see text] A novel modification of the classical Julia-Lythgoe olefination, using sulfoxides instead of sulfones, affords, after in situ benzoylation and SmI2/HMPA- or DMPU-mediated reductive elimination, 1,2-di-, tri-, and tetrasubstituted olefins in moderate to excellent yields and E/Z selectivity. The conditions are mild, and the procedure is broadly applicable.
authors.affiliation: Université Catholique de Louvain, Département de Chimie, Bâtiment Lavoisier, Place Louis Pasteur 1, B-1348 Louvain-la-Neuve, Belgium.
authors.forename: Jirí
authors.initials: J
authors.lastname: Pospísil
authors.forename: Tomás
authors.initials: T
authors.lastname: Pospísil
authors.forename: István E
authors.initials: IE
authors.lastname: Markó