Constitutive synthesis of enzymes involved in 2-aminophenol metabolism and inducible synthesis of enzymes involved in benzoate, p-hydroxybenzoate, and protocatechuate metabolism in Pseudomonas sp. strain AP-3.
Pseudomonas sp. strain AP-3 grows on benzoate, p-hydroxybenzoate, protocatechuate, and 2-aminophenol as sole carbon and energy source. This strain converted benzoate and p-hydroxybenzoate to catechol and protocatechuate respectively, which were metabolized via the ortho-cleavage pathway. The enzymes responsible for these reactions were shown to be inducible. In contrast, strain AP-3 constitutively expresses the enzymes involved in the metabolism of 2-aminophenol.
Takenaka
Shinji
S
Department of Biofunctional Chemistry, Faculty of Agriculture, Kobe University, Kobe, Japan.
Setyorini
Endang
E
Kim
Young-Ju
YJ
Murakami
Shuichiro
S
Aoki
Kenji
K
D000627:Aminophenols / Q000378:metabolism*; D001426:Bacterial Proteins / Q000378:metabolism; D001565:Benzoates / Q000378:metabolism*; D049308:Dioxygenases / Q000378:metabolism; D004790:Enzyme Induction; D062385:Hydroxybenzoates / Q000378:metabolism*; D008956:Models, Chemical; D015394:Molecular Structure; D010226:Parabens / Q000378:metabolism*; D011549:Pseudomonas / Q000201:enzymology*
D000627:Aminophenols; D001426:Bacterial Proteins; D001565:Benzoates; D062385:Hydroxybenzoates; D010226:Parabens; C027667:2-aminophenol; C009091:protocatechuic acid; D049308:Dioxygenases; C038193:4-hydroxybenzoic acid