T regulatory cells and allergy.
Anergy, tolerance and active suppression may not be independent events, but rather involve similar mechanisms and cell types in immune regulation. Induction of allergen-specific T(Reg) cells seems essential for maintaining a healthy immune response towards allergens. By utilizing multiple secreted cytokines and surface molecules, antigen-specific T(Reg) cells may re-direct an inappropriate immune response against allergens or auto-antigens.
Taylor
Alison
A
Swiss Institute of Allergy and Asthma Research (SIAF), Davos, Switzerland.
Verhagen
Johan
J
Akdis
Cezmi A
CA
Akdis
Mübeccel
M
D003888:Desensitization, Immunologic; D006967:Hypersensitivity / Q000276:immunology*; D007249:Inflammation / Q000276:immunology; D008213:Lymphocyte Activation / Q000502:physiology; D013601:T-Lymphocytes / Q000502:physiology*