[Celiac disease in adults: histological and morphometric data].
A morphologic and morphometric study of duodenal mucosal biopsies obtained from 90 patients suffering of celiac sprue was done. The results were compared with clinical, serological features as well as with information on inheritance. The diagnosis of celiac sprue was made when there was a combination of both specific clinical and serological signs with chronic atrophic mucosal changes in the duodenum correlating with morphometrical data. It was concluded that the lack of one of the mentioned parameters makes the diagnosis invalid and the patient needs further observation.
Kalinina
E Iu
EIu
Anichkov
N M
NM
D000293:Adolescent; D000328:Adult; D002446:Celiac Disease / Q000175:diagnosis / Q000235:genetics / Q000473:pathology*; D004386:Duodenum / Q000473:pathology*; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008297:Male; D008875:Middle Aged