title: [Measurement of peak inspiratory flow with asthma: effect of inhaled beta2-stimulant].
abstract: This study was designed to evaluate peak inspiratory flow (PIF) and peak expiratory flow (PEF) in 24 patients with mild asthma. After inhalation of a beta2-stimulant (beta2), PIF significantly increased from 173.0 +/- 67.0 (range 70-300 L/min) to 194.0 +/- 66.7 after 1 minute, and to 199.3 +/- 63.0 after 15 minutes (p < 0.0025, and p < 0.008, respectively). PEF also significantly increased. The previous inhalation of beta2 improved the efficacy of inhalation of dry powder. This evidence should be considered in performing patient education for effective methods of inhalation.
authors.affiliation: Takamatsu Municipal Hospital Division of Pharmacy.
authors.forename: Keiko
authors.initials: K
authors.lastname: Shimizu
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Yamazaki
authors.forename: Nobuhito
authors.initials: N
authors.lastname: Kishimoto
authors.forename: Shinya
authors.initials: S
authors.lastname: Tada
authors.forename: Nobuo
authors.initials: N
authors.lastname: Ueda
authors.forename: Jiro
authors.initials: J
authors.lastname: Fujita
authors.forename: Tadashi
authors.initials: T
authors.lastname: Kamei
authors.forename: Hiroki
authors.initials: H
authors.lastname: Okada
authors.forename: Yuko
authors.initials: Y
authors.lastname: Arakawa
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakamura
mesh_terms: D000280:Administration, Inhalation; D000318:Adrenergic beta-Agonists / Q000008:administration & dosage* / Q000627:therapeutic use; D000328:Adult; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009330:Nebulizers and Vaporizers; D010366:Peak Expiratory Flow Rate / Q000187:drug effects*
chemical_list: D000318:Adrenergic beta-Agonists; D018927:Anti-Asthmatic Agents