[28-year-old woman with Goodpasture's syndrome and nonspecific colitis].
Goodpasture's syndrome usually becomes manifest with progressive glomerulonephritis and pulmonary hemorrhage. The diagnostic hallmark is the demonstration of anti-basement membrane anti-alpha3 type IV collagen antibodies (anti-GMB antibodies) in patient sera. Herein is reported the case of 28-year-old woman with Goodpasture's syndrome who developed the acute symptoms of nonspecific colitis which required surgical intervention. Immunosuppression along with plasmapheresis was successful in the treatment of life-threatening pulmonary hemorrhage, but not for the improvement of renal function.
Jóźwiak
Lucyna
L
Katedra i Klinika Nefrologii AM, Lublinie.
Orłowska-Kowalik
Grazyna
G
Ksiazek
Andrzej
A
D000006:Abdomen, Acute / Q000209:etiology; D000328:Adult; D019867:Anti-Glomerular Basement Membrane Disease / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology / Q000601:surgery; D000906:Antibodies / Q000097:blood*; D001323:Autoantibodies; D001485:Basement Membrane / Q000276:immunology; D003092:Colitis / Q000150:complications* / Q000601:surgery; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans
D000906:Antibodies; D001323:Autoantibodies; C051951:antiglomerular basement membrane antibody