title: Brooke-Spiegler syndrome: treatment with laser ablation.
abstract: Brooke-Spiegler syndrome is a rare genetic condition associated with adnexal and epidermal tumours. Facial trichoepitheliomas and cylindromas are particularly distressing to sufferers. Conventional treatment can be followed by recurrence. We report a case with disfiguring trichoepithelioma treated with erbium:Yag and CO2 laser, achieving a good cosmetic result without recurrence after 2 years. Brooke-Spiegler syndrome and its treatment are reviewed.
authors.affiliation: Department of Dermatology, St Helier Hospital, Carshalton, UK. DeepakRallan@aol.com
authors.forename: D
authors.initials: D
authors.lastname: Rallan
authors.forename: C C
authors.initials: CC
authors.lastname: Harland
mesh_terms: D000328:Adult; D005153:Facial Neoplasms / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D053685:Laser Therapy; D018295:Neoplasms, Basal Cell / Q000532:radiotherapy; D009386:Neoplastic Syndromes, Hereditary / Q000532:radiotherapy*; D012878:Skin Neoplasms / Q000532:radiotherapy; D013577:Syndrome