Molecular cloning and sequences of interleukin-10 in the Djungarian (Phodopus sungorus), Chinese (Cricetulus griseus), and Syrian (Mesocricetus auratus) hamster.
Interleukin 10 (IL-10) genes of Djungarian, Chinese, and Syrian hamsters were cloned. The clones of IL-10 consisted of 537 bp nucleotides and 178 amino acids in full length, and the nucleotide and amino acid sequences exhibited a high degree of homology with those of the mouse and human. Since the number and position of signal sequences, N-glycosylations and cysteine sites in the IL-10 amino acid sequences of the hamsters were the same as those of the mouse, we suggest that the IL-10 molecular structures of the hamster are closer to that of the mouse than human.
Uchida
Yuko
Y
Department of Veterinary Parasitology, Nippon Veterinary and Animal Science University, Musashino, Tokyo 180-8602, Japan.
Ike
Kazunori
K
Katayama
Nami
N
Oguni
Yoshinobu
Y
Imai
Soichi
S
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D006224:Cricetinae / Q000276:immunology*; D003412:Cricetulus / Q000276:immunology; D016753:Interleukin-10 / Q000737:chemistry*; D008647:Mesocricetus / Q000276:immunology; D008969:Molecular Sequence Data; D017111:Phodopus / Q000276:immunology; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity
D016753:Interleukin-10