title: Hemichorea-hemiballismus may respond to topiramate.
abstract: Topiramate is a broad-spectrum anticonvulsant that is now widely used for adult and pediatric epilepsy. In a singular case, topiramate was recently reported to benefit vascular hemichorea-hemiballismus. The authors describe three cases of hemichorea-hemiballismus, one of vascular etiology and two of metabolic etiology, effectively treated with topiramate.
authors.affiliation: Department of Neurology, Mayo Clinic, Scottsdale, Arizona 85259, USA.
authors.forename: Erika
authors.initials: E
authors.lastname: Driver-Dunckley
authors.forename: Virgilio Gerald H
authors.initials: VG
authors.lastname: Evidente
mesh_terms: D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use*; D002819:Chorea / Q000188:drug therapy* / Q000209:etiology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D020820:Dyskinesias / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005632:Fructose / Q000031:analogs & derivatives* / Q000627:therapeutic use; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D006943:Hyperglycemia / Q000150:complications; D008297:Male; D008875:Middle Aged; D020521:Stroke / Q000188:drug therapy; D000077236:Topiramate
chemical_list: D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose