title: Atypical headache after prolonged treatment with nasal continuous positive airway pressure.
abstract: We report a case of atraumatic pneumocephalus associated with prolonged use of nasal continuous positive airway pressure. Initial symptoms included headache, ataxia, vertigo, and a "gurgling" sensation in the head; and a CT image showed small air bubbles along the falx of cerebrum and adjacent to the temporal epidural spaces bilaterally. Although no evidence of cerebrospinal fluid (CSF) leak was either reported by the patient or found at initial clinical examination, subsequent nasal discharge tested positive for beta2-transferrin, a finding consistent with CSF leak in the paranasal sinus region or through the cribriform plate. To try to prevent infection from an open communication between the paranasal sinuses and intracranial structures, an attempt should be made to localize the anatomic defect.
authors.affiliation: Department of Neurology, Kaiser Permanente Medical Center, Santa Rosa, CA 95403, USA.
authors.forename: Allan L
authors.initials: AL
authors.lastname: Bernstein
authors.forename: John
authors.initials: J
authors.lastname: Cassidy
authors.forename: Robert
authors.initials: R
authors.lastname: Duchynski
authors.forename: Stephen S
authors.initials: SS
authors.lastname: Eisenberg
mesh_terms: D000368:Aged; D045422:Continuous Positive Airway Pressure / Q000009:adverse effects*; D005260:Female; D006261:Headache / Q000209:etiology*; D006801:Humans; D011007:Pneumocephalus / Q000209:etiology*; D013997:Time Factors