title: DNA-BAR: distinguisher selection for DNA barcoding.
abstract: DNA-BAR is a software package for selecting DNA probes (henceforth referred to as distinguishers) that can be used in genomic-based identification of microorganisms. Given the genomic sequences of the microorganisms, DNA-BAR finds a near-minimum number of distinguishers yielding a distinct hybridization pattern for each microorganism. Selected distinguishers satisfy user specified bounds on length, melting temperature and GC content, as well as redundancy and cross-hybridization constraints.
authors.affiliation: Department of Computer Science, University of Illinois at Chicago, Chicago, IL 60607-7053, USA.
authors.forename: B
authors.initials: B
authors.lastname: DasGupta
authors.forename: K M
authors.initials: KM
authors.lastname: Konwar
authors.forename: I I
authors.initials: II
authors.lastname: Mandoiu
authors.forename: A A
authors.initials: AA
authors.lastname: Shvartsman
mesh_terms: D000465:Algorithms; D002874:Chromosome Mapping / Q000379:methods*; D004247:DNA / Q000737:chemistry* / Q000235:genetics*; D017403:In Situ Hybridization / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software
chemical_list: D004247:DNA