title: Interactive simulation system for artificial ventilation on the internet: virtual ventilator.
abstract: OBJECTIVE
  To develop an interactive simulation system "virtual ventilator" that demonstrates the dynamics of pressure and flow in the respiratory system under the combination of spontaneous breathing, ventilation modes, and ventilator options. The simulation system was designed to be used by unexperienced health care professionals as a self-training tool.
  
  
  METHODS
  The system consists of a simulation controller and three modules: respiratory, spontaneous breath, and ventilator. The respiratory module models the respiratory system by three resistances representing the main airway, the right and left lungs, and two compliances also representing the right and left lungs. The spontaneous breath module generates inspiratory negative pressure produced by a patient. The ventilator module generates driving force of pressure or flow according to the combination of the ventilation mode and options. These forces are given to the respiratory module through the simulation controller.
  
  
  RESULTS
  The simulation system was developed using HTML, VBScript (3000 lines, 100 kB) and ActiveX control (120 kB), and runs on Internet Explorer (5.5 or higher). The spontaneous breath is defined by a frequency, amplitude and inspiratory patterns in the spontaneous breath module. The user can construct a ventilation mode by setting a control variable, phase variables (trigger, limit, and cycle), and options. Available ventilation modes are: controlled mechanical ventilation (CMV), continuous positive airway pressure, synchronized intermittent mandatory ventilation (SIMV), pressure support ventilation (PSV), SIMV + PSV, pressure-controlled ventilation (PCV), pressure-regulated volume control (PRVC), proportional assisted ventilation, mandatory minute ventilation (MMV), bilevel positive airway pressure (BiPAP). The simulation system demonstrates in a graph and animation the airway pressure, flow, and volume of the respiratory system during mechanical ventilation both with and without spontaneous breathing.
  
  
  CONCLUSIONS
  We developed a web application that demonstrated the respiratory mechanics and the basic theory of ventilation mode.
authors.affiliation: Department of Medical Informatics, School of Allied Health Sciences, Kitasato University, Japan. take@nc.kitasato-u.ac.jp
authors.forename: Akihiro
authors.initials: A
authors.lastname: Takeuchi
authors.forename: Tadashi
authors.initials: T
authors.lastname: Abe
authors.forename: Minoru
authors.initials: M
authors.lastname: Hirose
authors.forename: Koichi
authors.initials: K
authors.lastname: Kamioka
authors.forename: Atsushi
authors.initials: A
authors.lastname: Hamada
authors.forename: Noriaki
authors.initials: N
authors.lastname: Ikeda
mesh_terms: D003198:Computer Simulation; D006801:Humans; D020407:Internet; D011312:Pressure; D012119:Respiration; D012121:Respiration, Artificial / Q000379:methods*; D015656:Respiratory Mechanics; D014584:User-Computer Interface