Investigation of herpes simplex virus DNA in pityriasis rosea by polymerase chain reaction.
BACKGROUND
Pityriasis rosea (PR) is an acute, inflammatory disease of unknown cause. Clinical and experimental findings indicate an infectious etiology of PR. Our purpose is to examine the skin lesions and blood samples of PR patients by polymerase chain reaction (PCR) for the presence of HSV type 1 and 2 DNA.


METHODS
The lesional skin biopsies from 10 patients and blood samples from two randomized patients with clinically and histologically confirmed pityriasis rosea were examined by PCR.


RESULTS
No HSV 1 and HSV 2 DNA was detected in the lesional biopsy and blood samples.


CONCLUSIONS
We could not identify a relationship between HSV 1, HSV 2 and PR.
Bozdag
Kübra Eren
KE
Department of Dermatology, Atatürk Training and Research Hospital, Izmir, Turkey. bozdag@egenet.com.tr
Güven
Füsun Ozder
FO
Zeytinoglu
Aysin
A
Erensoy
Selda
S
Karaman
Ahmet
A
Bilgiç
Altýnay
A
D000328:Adult; D001706:Biopsy; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D018259:Herpesvirus 1, Human / Q000302:isolation & purification*; D018258:Herpesvirus 2, Human / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D017515:Pityriasis Rosea / Q000097:blood / Q000473:pathology / Q000821:virology*; D016133:Polymerase Chain Reaction; D012867:Skin / Q000473:pathology
D004279:DNA, Viral