Uterine gastrointestinal stromal tumour (GIST).
BACKGROUND
Gastrointestinal stromal tumours (GIST) are mesenchymal tumours which mostly arise in the gastrointestinal tract showing positive CD117 immunohistochemical staining. In recent years, other locations such as the mesentery and the retroperitoneum have been reported.


METHODS
A 77-year-old woman presented with a pelvic mass, raising the suspicion of an ovarian or a uterine tumour. During laparotomy, a ruptured process arising from the uterus was seen and removed. Histologic features, immunophenotype and genotype of the tumour supported the diagnosis of a GIST.


CONCLUSIONS
To the best of our knowledge, this is the first case of a primary GIST presenting as a uterine mass. Because of recent advances in GIST-therapy, making a correct diagnosis has major clinical implications.
Wingen
Chantal B M
CB
Department of Obstetrics and Gynaecology, University Hospital Maastricht, P. Debeyelaan 25, 6229 HX Maastricht, The Netherlands. chantal@wingen.nl
Pauwels
Patrick A A
PA
Debiec-Rychter
Maria
M
van Gemert
Wim G
WG
Vos
M Caroline
MC
D000368:Aged; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000473:pathology* / Q000601:surgery; D006801:Humans; D014594:Uterine Neoplasms / Q000473:pathology* / Q000601:surgery