title: Hypertrophic pyloric stenosis in twins: same genes or same environments?
abstract: The aetiology of infantile hypertrophic pyloric stenosis (IHPS) remains obscure. Cases in twins, usually monozygotic, have been sporadically reported as evidence for the genetic origin of the disease. We present a case of IHPS in a pair of dizygotic male twins together with a review of the literature, focusing on the question of whether the twin cases actually support a genetic or an acquired nature of IHPS.
authors.affiliation: Department of Paediatric Surgery, University of Crete, P.O. Box 2208, Heraklion 71003, Greece.
authors.forename: K
authors.initials: K
authors.lastname: Velaoras
authors.forename: M
authors.initials: M
authors.lastname: Bitsori
authors.forename: E
authors.initials: E
authors.lastname: Galanakis
authors.forename: G
authors.initials: G
authors.lastname: Charissis
mesh_terms: D020022:Genetic Predisposition to Disease; D006801:Humans; D007223:Infant; D008297:Male; D046248:Pyloric Stenosis, Hypertrophic / Q000175:diagnosis / Q000209:etiology / Q000235:genetics / Q000601:surgery*; D014429:Twins, Dizygotic