title: [Interdigitating dendritic cell sarcoma-a case report with literature review].
abstract: OBJECTIVE
  To report a case of interdigitating dendritic cell sarcoma (IDCS).
  
  
  METHODS
  The patient was a 41-year-old man with a lymph node bulging in the left neck. Laboratory examination of peripheral blood and bone marrow was abnormal. The diagnosis of IDCS was made by immunohistochemistry and electron microscopy. Treatment of this patient with ABVD regimen (adriamycin, bleomycin, vinblastine, dacarbazine) resulted in obvious improvement, but did not control the tumor infiltration.
  
  
  CONCLUSIONS
  IDCS has no distinctive clinical or pathohistological characteristics. Immunohistochemistry and electron microscopy are crucial in distinguishing it from other histiocytic/dendritic cell neoplasms. IDCS displays an aggressive behaviour, and the responses to chemotherapy are variable.
authors.affiliation: Jiangsu Institute of Hematology, First Affiliated Hospital, Suzhou University, Suzhou 215006, China.
authors.forename: Wen-Jin
authors.initials: WJ
authors.lastname: Gao
authors.forename: Ri
authors.initials: R
authors.lastname: Zhang
authors.forename: Hong-Xia
authors.initials: HX
authors.lastname: Qiu
authors.forename: Yi-Min
authors.initials: YM
authors.lastname: Shen
authors.forename: Xu-Hui
authors.initials: XH
authors.lastname: Zhang
authors.forename: Sheng-Li
authors.initials: SL
authors.lastname: Xue
authors.forename: Yue
authors.initials: Y
authors.lastname: Han
mesh_terms: D000328:Adult; D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D003606:Dacarbazine / Q000008:administration & dosage; D054739:Dendritic Cell Sarcoma, Interdigitating / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism*; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009418:S100 Proteins / Q000032:analysis; D016896:Treatment Outcome; D014747:Vinblastine / Q000008:administration & dosage; D000097382:CD68 Molecule
chemical_list: D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D001761:Bleomycin; D003606:Dacarbazine; D004317:Doxorubicin; D009418:S100 Proteins; D014747:Vinblastine; C067980:CD68 antigen, human; D000097382:CD68 Molecule