Guillain-Barré-like syndrome associated with olanzapine hypersensitivity reaction.
Olanzapine is the most commonly prescribed atypical antipsychotic drug. Recently there has been increased concern over possible adverse metabolic effects of this drug. The authors describe the first case of Guillain-Barré-like syndrome associated with an olanzapine hypersensitivity reaction. The presence of progressive numbness, motor weakness, or pain in the limbs of patients receiving olanzapine should raise suspicion of Guillain-Barré syndrome.
Benito-León
Julián
J
Department of Neurology, Móstoles General Hospital, Madrid, Spain. jbenitol@meditex.es
Mitchell
Alex J
AJ
D014150:Antipsychotic Agents / Q000009:adverse effects*; D001569:Benzodiazepines / Q000009:adverse effects; D004342:Drug Hypersensitivity / Q000150:complications*; D004569:Electroencephalography; D020275:Guillain-Barre Syndrome / Q000209:etiology*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D000077152:Olanzapine; D014607:Uveomeningoencephalitic Syndrome / Q000150:complications
D014150:Antipsychotic Agents; D016756:Immunoglobulins, Intravenous; D001569:Benzodiazepines; D000077152:Olanzapine