Antimicrobial resistance determinants and future control.
At the beginning of the 21st century, antimicrobial resistance is common, has developed against every class of antimicrobial drug, and appears to be spreading into new clinical niches. We describe determinants likely to influence the future epidemiology and health impact of antimicrobial-resistant infections. Understanding these factors will ultimately optimize preventive strategies for an unpredictable future.
Harbarth
Stephan
S
University of Geneva Hospitals, Geneva, Switzerland. stephen.harbarth@hcuge.ch
Samore
Matthew H
MH
D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects*; D001424:Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D024881:Drug Resistance, Bacterial; D006801:Humans; D010818:Practice Patterns, Physicians'
D000900:Anti-Bacterial Agents