title: Phenytoin may increase the efficacy of temozolomide by methylating DNA-repair enzyme, O6-methylguanine-DNA methyltransferase in patients with glioblastoma.
authors.forename: Ozden
authors.initials: O
authors.lastname: Altundag
authors.forename: Kadri
authors.initials: K
authors.lastname: Altundag
authors.forename: Cem
authors.initials: C
authors.lastname: Boruban
authors.forename: Muzaffer B
authors.initials: MB
authors.lastname: Altundag
authors.forename: Selahattin
authors.initials: S
authors.lastname: Turen
mesh_terms: D004260:DNA Repair; D003606:Dacarbazine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000627:therapeutic use; D005909:Glioblastoma / Q000188:drug therapy*; D006801:Humans; D008745:Methylation; D019853:O(6)-Methylguanine-DNA Methyltransferase / Q000378:metabolism*; D010672:Phenytoin / Q000378:metabolism*; D000077204:Temozolomide
chemical_list: D010672:Phenytoin; D003606:Dacarbazine; D019853:O(6)-Methylguanine-DNA Methyltransferase; D000077204:Temozolomide