[Fuchs uveitis syndrome--heterochromia is no "conditio sine qua non"].
Fuchs uveitis syndrome (FUS) is typically a unilateral, chronic, low-grade inflammation of the anterior segment which manifests in young adulthood. It is underdiagnosed because of its variable clinical spectrum. Although it can mimic various forms of anterior uveitis, it is important to make the correct diagnosis, based on clinical grounds, because both the management and prognosis differ from those of other uveitides. While its etiology remains unknown, it is possible that the disease has multiple causes that lead through different pathogenic mechanisms to the same clinical entity. Although many patients do not require treatment, it is not a benign condition, as often perceived. The high incidence of glaucoma makes it mandatory that all patients with FUS should be screened at regular intervals, even if they are not being actively treated and are relatively asymptomatic.
Becker
M D
MD
Interdisziplinäres Uveitiszentrum, Universität, Heidelberg.
Zierhut
M
M
D003937:Diagnosis, Differential; D005642:Fuchs' Endothelial Dystrophy / Q000175:diagnosis* / Q000628:therapy*; D005901:Glaucoma / Q000517:prevention & control*; D006801:Humans; D010859:Pigmentation Disorders / Q000175:diagnosis* / Q000628:therapy*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D013577:Syndrome; D014605:Uveitis / Q000175:diagnosis* / Q000628:therapy*