Successful medical treatment of multiple brain abscesses due to Nocardia farcinica in a paediatric renal transplant recipient.
Brain abscesses caused by Nocardia are rare, but it is very important to detect and treat them early because the associated mortality is 3 times higher than that associated with other bacterial brain abscesses. This infection is prevalent among adults on long-term immunosuppressive therapy; we report the case of a male kidney transplant recipient aged 12.7 years who developed early multiple Nocardia-induced brain abscesses that were successfully treated with linezolid, a novel antibiotic therapy.
Viganò
Sara Maria
SM
ICP Pediatric Nephrology, Dialysis and Transplantation Unit, Milan, Italy.
Edefonti
Alberto
A
Ferraresso
Mariano
M
Ranzi
Maria Luisa
ML
Grossi
Paolo
P
Righini
Andrea
A
Rusconi
Roberto
R
Santambrogio
Luigi
L
Ghio
Luciana
L
D000081:Acetamides / Q000627:therapeutic use*; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001922:Brain Abscess / Q000188:drug therapy*; D002648:Child; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D000069349:Linezolid; D008297:Male; D009617:Nocardia Infections / Q000188:drug therapy*; D023303:Oxazolidinones / Q000627:therapeutic use*
D000081:Acetamides; D000890:Anti-Infective Agents; D023303:Oxazolidinones; D000069349:Linezolid