title: Changing periodontal concepts: treatment considerations.
abstract: Many clinical trials conducted during the last decade have clarified controversial issues and resulted in changed periodontal paradigms. These modified concepts have therapeutic implications. Some salient altered periodontal concepts include the following: The mere presence of pathogens will not initiate periodontal diseases. Most subgingival bacteria reside in biofilms. Periodontal diseases are infections. Periodontal pathogens can be transferred between family members. The host response can be protective and destructive. Gingivitis does not usually proceed to periodontitis. Risk factors in conjunction with bacteria and the host response can affect the severity of disease, patterns of destruction, and the response to therapy. Many medical conditions (eg, diabetes, smoking, and HIV infection) may predispose patients to periodontitis. Associations between periodontitis and a number of systemic ailments (eg, diabetes, adverse pregnancy outcomes, and cardiovascular disease) have been detected and are being investigated to determine if there is a cause-and-effect relationship. Diagnostic and therapeutic implications of these altered paradigms are addressed throughout the article.
authors.affiliation: Department of Periodontology, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA.
authors.forename: Gary
authors.initials: G
authors.lastname: Greenstein
mesh_terms: D001424:Bacterial Infections / Q000382:microbiology; D018441:Biofilms; D004194:Disease; D018450:Disease Progression; D005260:Female; D005891:Gingivitis / Q000503:physiopathology; D006801:Humans; D010510:Periodontal Diseases / Q000382:microbiology / Q000503:physiopathology / Q000628:therapy*; D011247:Pregnancy; D011256:Pregnancy Outcome; D012307:Risk Factors