title: [Preservation of laryngeal function in surgical treatment of pyriform sinus carcinoma].
abstract: OBJECTIVE
  To explore the feasibility and the related surgical techniques of laryngeal function preservation in surgical treatment of pyriform sinus cancer.
  
  
  METHODS
  Two hundred and thirty cases (stage I, 6; stage II, 10; stage III, 91; stage IV, 123) with pyriform sinus cancer were treated surgically from 1978 to 1996 in the Department of Otorhinolaryngology of Qilu Hospital of Shandong University. The methods of removing tumor and repairing surgical defects were depended on the extension of lesions. The laryngeal and pharyngeal functions were rebuilt by normal tissue preserved with lesions entirely removed. One hundred and fifty-eight cases were surgically treated with laryngeal functions preserved and 72 cases total laryngectomy. The most of the cases received postoperative radiotherapy.
  
  
  RESULTS
  The overall 3 and 5 year survival rates were 67.4% (155/230) and 48.3% (111/230) respectively. For stage I, the survival rate was 5/6; stage 11, 70.0% (7/10); stage III, 57.1% (52/91) and stage IV, 38.2% (47/123); the 3 and 5 year survival rates in functionally preserved group were 67.7% (107/158) and 50.0% (79/158), while in none functional group were 66.7% (48/72) and 43.1% (31/72), respectively. 75.3% (119/158) patients have laryngeal functions (voice,respiration and deglutition) completely restored and 24.7% (39/ 158) partially restored(voice and deglutition).
  
  
  CONCLUSIONS
  The preservative surgery is feasible for the selected pyriform sinus cancer cases. Choosing and following optimum surgical methods is a prerequisite for improving the quality of life of the cases.
authors.affiliation: Department of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan 250012, China.
authors.forename: Xue-zhong
authors.initials: XZ
authors.lastname: Li
authors.forename: Li-qiang
authors.initials: LQ
authors.lastname: Zhang
authors.forename: Xin-liang
authors.initials: XL
authors.lastname: Pan
authors.forename: Guang
authors.initials: G
authors.lastname: Xie
authors.forename: Xin-yong
authors.initials: XY
authors.lastname: Luan
authors.forename: Tian-duo
authors.initials: TD
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D005260:Female; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000601:surgery*; D007830:Larynx / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010611:Pharyngectomy / Q000379:methods*; D015996:Survival Rate; D016896:Treatment Outcome