title: Challenges in systematic reviews of economic analyses.
abstract: Economic analyses can provide valuable information for health care decision makers. Systematic reviews of economic analyses can integrate information from multiple studies and provide important insights by systematically examining how differences between models lead to different results. We use our experience in developing and implementing systematic reviews of economic analyses for the U.S. Preventive Services T ask Force, particularly our systematic review of the cost-effectiveness of colorectal cancer screening, to illustrate key methodologic challenges and suggest a framework for other researchers in this area.
authors.affiliation: University of North Carolina, Chapel Hill, North Carolina 27599-7110, USA. Pignone@med.unc.edu
authors.forename: Michael
authors.initials: M
authors.lastname: Pignone
authors.forename: Somnath
authors.initials: S
authors.lastname: Saha
authors.forename: Tom
authors.initials: T
authors.lastname: Hoerger
authors.forename: Kathleen N
authors.initials: KN
authors.lastname: Lohr
authors.forename: Steven
authors.initials: S
authors.lastname: Teutsch
authors.forename: Jeanne
authors.initials: J
authors.lastname: Mandelblatt
mesh_terms: D015179:Colorectal Neoplasms / Q000191:economics; D003362:Cost-Benefit Analysis; D019317:Evidence-Based Medicine / Q000379:methods*; D017048:Health Care Costs; D006801:Humans; D018803:Models, Economic; D012196:Review Literature as Topic