Fatal pulmonary infection in a leukaemic patient caused by Hormographiella aspergillata.
A case of autopsy-proven fungal pneumonia in a relapsed leukaemia patient is reported. The fungus Hormographiella aspergillata was cultured from two bronchoalveolar fluid samples and identified through morphological examination and ITS2 sequence analysis. In addition, galactomannan was detected in eight consecutive serum samples, which suggested a co-infection with Aspergillus species. The patient was treated with caspofungin.
Lagrou
Katrien
K
Immunology and Microbiology1, Hematology2, Internal Medicine3 and Pathology5, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium 4Laboratory for Microbiology, MCH, Maria Theresiastraat 63A, 3000 Leuven, Belgium.
Massonet
Caroline
C
Immunology and Microbiology1, Hematology2, Internal Medicine3 and Pathology5, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium 4Laboratory for Microbiology, MCH, Maria Theresiastraat 63A, 3000 Leuven, Belgium.
Theunissen
Koen
K
Immunology and Microbiology1, Hematology2, Internal Medicine3 and Pathology5, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium 4Laboratory for Microbiology, MCH, Maria Theresiastraat 63A, 3000 Leuven, Belgium.
Meersseman
Wouter
W
Immunology and Microbiology1, Hematology2, Internal Medicine3 and Pathology5, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium 4Laboratory for Microbiology, MCH, Maria Theresiastraat 63A, 3000 Leuven, Belgium.
Lontie
Marc
M
Immunology and Microbiology1, Hematology2, Internal Medicine3 and Pathology5, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium 4Laboratory for Microbiology, MCH, Maria Theresiastraat 63A, 3000 Leuven, Belgium.
Verbeken
Eric
E
Immunology and Microbiology1, Hematology2, Internal Medicine3 and Pathology5, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium 4Laboratory for Microbiology, MCH, Maria Theresiastraat 63A, 3000 Leuven, Belgium.
Van Eldere
Johan
J
Immunology and Microbiology1, Hematology2, Internal Medicine3 and Pathology5, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium 4Laboratory for Microbiology, MCH, Maria Theresiastraat 63A, 3000 Leuven, Belgium.
Maertens
Johan
J
Immunology and Microbiology1, Hematology2, Internal Medicine3 and Pathology5, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium 4Laboratory for Microbiology, MCH, Maria Theresiastraat 63A, 3000 Leuven, Belgium.
D000328:Adult; D000363:Agaricales / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D001228:Aspergillosis / Q000150:complications* / Q000175:diagnosis; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology; D003302:Coprinus / Q000145:classification / Q000302:isolation & purification; D021901:DNA, Intergenic / Q000737:chemistry; D017809:Fatal Outcome; D005690:Galactose / Q000031:analogs & derivatives; D006801:Humans; D015479:Leukemia, Myelomonocytic, Acute / Q000150:complications*; D008168:Lung / Q000000981:diagnostic imaging / Q000382:microbiology; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000382:microbiology*; D008297:Male; D008351:Mannans / Q000097:blood; D014057:Tomography, X-Ray Computed
D021901:DNA, Intergenic; D008351:Mannans; C012990:galactomannan; D005690:Galactose