Bacterial species diversity in cigarettes linked to an investigation of severe pneumonitis in U.S. Military personnel deployed in operation iraqi freedom.
This report presents results from a study on the bacterial diversity of cigarette brands collected from military personnel during the U.S. Army's investigation of a series of cases of acute eosinophilic pneumonitis in military personnel deployed in Operation Iraqi Freedom. Eight species of Bacillus, including five new species, and one new species of Kurthia were isolated from the cigarettes. Some of these species have been identified elsewhere as causes of hypersensitivity pneumonitis and other respiratory syndromes. All of the isolates were facultative anaerobes, and many displayed mucoid growth under anaerobic conditions. In addition, many isolates also displayed the ability to form surface biofilms under liquid culture. Although biofilm formation and mucoid growth were not correlated, the former was found to be much more pronounced under anaerobic conditions as opposed to aerobic ones. The implications of these findings are discussed.
Rooney
Alejandro P
AP
Microbial Genomics and Bioprocessing Research Unit, Agricultural Research Service, U.S. Department of Agriculture, Peoria, IL 61604, USA. rooney@ncaur.usda.gov
Swezey
James L
JL
Wicklow
Donald T
DT
McAtee
Matthew J
MJ
D000208:Acute Disease; D001419:Bacteria / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D004196:Disease Outbreaks; D014644:Genetic Variation; D006801:Humans; D008877:Middle East / Q000453:epidemiology; D008889:Military Personnel; D011014:Pneumonia / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D012907:Smoking / Q000009:adverse effects*; D013577:Syndrome; D014026:Nicotiana / Q000382:microbiology*; D014481:United States; D014857:Warfare