title: Macrolide- and telithromycin-resistant Streptococcus pyogenes, Belgium, 1999-2003.
abstract: We found a 13% macrolide resistance in 3,866 Streptococcus pyogenes isolated from tonsillopharyngitis patients; 59% macrolide-resistant isolates were distributed in 5 clones, suggesting the importance of both resistance gene transfer and clonal dissemination in the spread of these organisms. We also report one of the largest collections of telithromycin-resistant isolates.
authors.affiliation: University of Antwerp, Antwerp, Belgium. surbhi.malhotra@ua.ac.be
authors.forename: Surbhi
authors.initials: S
authors.lastname: Malhotra-Kumar
authors.forename: Christine
authors.initials: C
authors.lastname: Lammens
authors.forename: Sabine
authors.initials: S
authors.lastname: Chapelle
authors.forename: Monique
authors.initials: M
authors.lastname: Wijdooghe
authors.forename: Jasper
authors.initials: J
authors.lastname: Piessens
authors.forename: Koen
authors.initials: K
authors.lastname: Van Herck
authors.forename: Herman
authors.initials: H
authors.lastname: Goossens
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial / Q000235:genetics; D006801:Humans; D007223:Infant; D048628:Ketolides / Q000494:pharmacology*; D018942:Macrolides / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011159:Population Surveillance; D013290:Streptococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000145:classification / Q000187:drug effects* / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D048628:Ketolides; D018942:Macrolides; C106791:telithromycin