title: Electroencephalography, Doppler vascular scanning, and single photon emission computed tomography in a child with hydranencephaly and intractable seizures.
abstract: In a child with hydranencephaly and refractory seizures, the electroencephalogram showed a flat isoelectric pattern with no significant slow waves or epileptiform activity; cranial computed tomography, magnetic resonance imaging, Doppler vascular scanning, and single photon emission computed tomography (SPECT) were done to define the pathogenesis of the seizures. The investigations were suggestive of a lack of significant cortical, subcortical, or thalamic structures with hypoplasia of the vermis and cerebellum. SPECT showed little activity in the base of the brain and cerebellum. The cause of the seizures remained unclear in spite of the investigations.
authors.affiliation: Department of Paediatrics, Faculty of Medicine and Health Services, United Arab Emirates University, Tawam Hospital, Al Ain. GururajA@uaeu.ac.ae
authors.forename: Aithala
authors.initials: A
authors.lastname: Gururaj
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Varady
authors.forename: László
authors.initials: L
authors.lastname: Sztriha
authors.forename: Li
authors.initials: L
authors.lastname: Al-Gazali
authors.forename: Waldemar
authors.initials: W
authors.lastname: Gorka
authors.forename: Michael
authors.initials: M
authors.lastname: Nork
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006832:Hydranencephaly / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D007231:Infant, Newborn; D015899:Tomography, Emission-Computed, Single-Photon; D017585:Ultrasonography, Doppler, Transcranial