title: In vivo study to assess the viability and mass effect of fascia injection in comparison with block fascia graft.
abstract: Recently, fat injection has gained favor among plastic surgeons for soft tissue augmentation. However, fat injections lose 50% of their volume after 1 year. The profession is in need of an injectable bulking material that gives a long-lasting improvement. Using 30 male rats, this study investigated the stability of the size and structure of the injected fascia autograft and compared it with surgically transplanted fascia. The fascia graft was harvested from the back of the rat, big, and divided into two equal pieces. The first piece was minced into a paste and injected subcutaneously on the anterior surface of the right ear. The other piece was transplanted subcutaneously on the anterior surface of the left ear. The grafts were observed for any sign of resorption over 1 to 6 months.Grossly, injection and transplantation sites were palpable at the end of the observation periods. Microscopic examination showed that injected fascia maintains its histomorphologic structure. These findings indicate that the injected fascia graft is well tolerated, and the size of the graft remained stable. According to this study, fascia injection can result in bulking material that gives a long-lasting improvement, and can be a viable alternative to other methods.
authors.affiliation: Y. Dikmen Mah. Urdün Cad. 45. Sok. 16/4 (Aytekinler Apt), Oran, Ankara 06700, Turkey. zuhtudemir@hotmail.com
authors.forename: Zühtü
authors.initials: Z
authors.lastname: Demir
authors.forename: Atilla
authors.initials: A
authors.lastname: Kurtay
authors.forename: Hifzi
authors.initials: H
authors.lastname: Velidedeoğlu
authors.forename: Mehmet Ali
authors.initials: MA
authors.lastname: Onur
authors.forename: Pergin
authors.initials: P
authors.lastname: Atilla
authors.forename: Canan
authors.initials: C
authors.lastname: Taş
authors.forename: Nur
authors.initials: N
authors.lastname: Cakar
mesh_terms: D000273:Adipose Tissue / Q000473:pathology / Q000637:transplantation*; D000818:Animals; D004425:Ear Cartilage / Q000473:pathology*; D005205:Fascia / Q000473:pathology / Q000637:transplantation*; D007279:Injections, Subcutaneous; D008297:Male; D051381:Rats; D013524:Surgical Flaps; D013997:Time Factors; D014182:Transplantation, Autologous; D019737:Transplants