title: Vascularisation of Norian CRS bone cement and its replacement by autologous bone when used for orbital reconstruction.
abstract: Various bone cements based on calcium phosphate have been used as adjuncts for repairing both the craniofacial and axial skeleton. Ideally these materials should provide initial strength and contour for the reconstruction, and be replaced over time by physiological absorption and bony deposition. Although there is evidence from animal models to support this, opportunities for human studies are rare. Here we offer clinical and histological evidence of this process.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Pinderfields Hospital, Wakefield, UK. paulchambers@doctors.org.uk
authors.forename: P A
authors.initials: PA
authors.lastname: Chambers
authors.forename: R A
authors.initials: RA
authors.lastname: Loukota
authors.forename: A S
authors.initials: AS
authors.lastname: High
mesh_terms: D000042:Absorption; D001843:Bone Cements / Q000627:therapeutic use*; D016723:Bone Remodeling / Q000502:physiology*; D018786:Bone Substitutes / Q000627:therapeutic use*; D002130:Calcium Phosphates / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D009915:Orbit / Q000502:physiology / Q000601:surgery*; D009917:Orbital Fractures / Q000601:surgery; D019651:Plastic Surgery Procedures; D015051:Zygomatic Fractures / Q000601:surgery
chemical_list: D001843:Bone Cements; D018786:Bone Substitutes; D002130:Calcium Phosphates; C496047:Norian SRS Cement