title: Retroperitoneoscopic donor nephrectomy: a retrospective, non-randomized comparison of early complications, donor and recipient outcome with the standard open approach.
abstract: OBJECTIVE
  We retrospectively performed a comparative analysis of retroperitoneoscopic and open donor nephrectomy in terms of donor complications, as well as recipient complications and functional graft outcome.
  
  
  METHODS
  A total of 134 donor nephrectomies including 69 open (ODN) and 65 retroperitoneoscopic (RDN) nephrectomies was analyzed retrospectively. Both groups were comparable in terms of age, body mass index (BMI), operating time (OPT), warm ischemia time (WIT) and blood loss.
  
  
  RESULTS
  There were no statistically significant differences with respect to recipient outcome, mean values for age, BMI, OPT and cold ischemia time (CIT). The overall donor complication rate did not differ. Early functional graft follow-up showed significant differences in 24 h-urine output between the two groups (p<0.001), but serum creatinine was comparable after 7, 30, 180 and 365 days. The early rejection rate in the recipients was similar in the two groups.
  
  
  CONCLUSIONS
  Retroperitoneoscopic donor nephrectomy (RDN) provides comparable perioperative features, such as operating time, warm ischemia time (WIT) and overall complication rate to the open donor nephrectomy (ODN). Additionally, it has no negative impact on recipients' operating time, graft ischemia and early graft function.
authors.affiliation: Department of Urology, Basel University Hospital, Spitalstr. 21, CH-4031 Basel, Switzerland. bachmanna@uhbs.ch
authors.forename: Alexander
authors.initials: A
authors.lastname: Bachmann
authors.forename: Thomas
authors.initials: T
authors.lastname: Wolff
authors.forename: Robin
authors.initials: R
authors.lastname: Ruszat
authors.forename: Olivier
authors.initials: O
authors.lastname: Giannini
authors.forename: Michael
authors.initials: M
authors.lastname: Dickenmann
authors.forename: Lorenz
authors.initials: L
authors.lastname: Gürke
authors.forename: Jürg
authors.initials: J
authors.lastname: Steiger
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Gasser
authors.forename: Christian G
authors.initials: CG
authors.lastname: Stief
authors.forename: Tullio
authors.initials: T
authors.lastname: Sulser
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection; D006801:Humans; D007431:Intraoperative Complications; D016030:Kidney Transplantation / Q000009:adverse effects / Q000379:methods; D010535:Laparoscopy; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000009:adverse effects / Q000379:methods; D011183:Postoperative Complications; D012189:Retrospective Studies; D013997:Time Factors