title: Obesity does not impact implantation rates or pregnancy outcome in women attempting conception through oocyte donation.
abstract: OBJECTIVE
  To independently evaluate the effect of body mass index (BMI) on implantation, pregnancy, and incidence of spontaneous miscarriage using the donor oocyte recipient model.
  
  
  METHODS
  Institutional Review Board-approved retrospective data analyses of donor oocyte cycles from 1999 to 2004.
  
  
  METHODS
  Private assisted reproductive technology (ART) center.
  
  
  METHODS
  Five hundred thirty-six first cycle recipients of donor oocytes.
  
  
  METHODS
  Data were collected from the first cycle of each donor oocyte recipient included in the study. The body mass index (BMI) of each recipient was calculated using the formula weight (in kilograms)/height (in meters squared). Patients were divided into four groups based on BMI: underweight, normal, overweight, and obese. Pregnancy outcomes in each group were compared.
  
  
  METHODS
  Body mass index, implantation rate, pregnancy rate (PR), miscarriage rate.
  
  
  RESULTS
  There were no statistically significant differences in the implantation rates, ongoing PRs, or spontaneous abortion rates among patients in the four BMI groups. When further divided into those patients receiving blastocyst vs. day 3 transfers, there was still no effect of BMI on implantation rate, PR, or loss rate among the blastocyst or day 3 donor oocyte recipients.
  
  
  CONCLUSIONS
  Body mass index has no adverse impact on implantation or reproductive outcome in donor oocyte recipients. Therefore, obesity does not appear to exert a negative effect on endometrial receptivity.
authors.affiliation: Division of Reproductive Endocrinology and Infertility, Emory University School of Medicine, Atlanta, Georgia, USA.
authors.forename: Allison
authors.initials: A
authors.lastname: Styne-Gross
authors.forename: Karen
authors.initials: K
authors.lastname: Elkind-Hirsch
authors.forename: Richard T
authors.initials: RT
authors.lastname: Scott
mesh_terms: D000328:Adult; D015992:Body Mass Index; D010064:Embryo Implantation / Q000502:physiology; D005260:Female; D005306:Fertilization / Q000502:physiology; D006801:Humans; D009765:Obesity / Q000453:epidemiology* / Q000503:physiopathology; D018587:Oocyte Donation / Q000379:methods / Q000706:statistics & numerical data; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D012189:Retrospective Studies