title: [On the interest of analyzing temperament in bipolar subjects].
abstract: Temperaments in bipolar subjects, as observed by Kraepelin and later re-dynamized and operationalized by Akiskal, have given rise to various studies, which results are hereby synthesized. In the light of these studies, the evaluation of temperaments allows to define subgroups of bipolar subjects, in order to sharpen diagnosis and therefore be able to propose more accurate treatment. A depressive temperament is linked to more frequent thymic relapses, on a depressive slope and it is associated with more frequent comorbid anxiety disorder and with an increased suicidal risk. A hyperthymic temperament is linked to manic relapses and is more likely to switch mood when patients were treated with antidepressants. A thymic episode that appears in a temperament of the opposite polarity will result in a mixed episode. Temperament evaluation is also helpful in choosing drug treatments. Practical clinical benefits can be gained from the study and analysis of those temperaments. As a further development, it could be useful to characterize euthymic period by a dimensional approach.
authors.affiliation: Centre Hospitalier Charles-Perrens, Département 3/47, Bâtiment Lescure, 121, rue de la Béchade, F-33076 Bordeaux cedex.
authors.forename: D
authors.initials: D
authors.lastname: Van den Bulke
authors.forename: C
authors.initials: C
authors.lastname: Henry
mesh_terms: D001008:Anxiety Disorders / Q000453:epidemiology / Q000523:psychology; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000453:epidemiology* / Q000523:psychology; D015897:Comorbidity; D003866:Depressive Disorder / Q000188:drug therapy / Q000453:epidemiology / Q000523:psychology; D006801:Humans; D010349:Patient Compliance / Q000706:statistics & numerical data; D013694:Temperament