Intron position conservation across eukaryotic lineages in tubulin genes.
A compilation of intron positions obtained from a large number of eukaryotic genomes across orthologous tubulins is explored for molecular evolution. Comparison of intron positions for 41 alpha, 80 beta, and 30 gamma tubulin genomic sequences indicates that the putative ancestral tubulin gene contained at least 19, 33, and 52 intron positions distributed at different sites in the coding regions for alpha, beta, and gamma tubulins, respectively. Many intron positions are old and are conserved across different eukaryotic lineages and intron distribution patterns are consistent with 'introns-early' hypothesis.
Perumal
Bagavathi S
BS
NCSV, MAE, Nanyang Technological University, 639798, Singapore.
Sakharkar
Kishore R
KR
Chow
Vincent Tak Kwong
VT
Pandjassarame
Kangueane
K
Sakharkar
Meena Kishore
MK
D000818:Animals; D017124:Conserved Sequence; D005057:Eukaryotic Cells / Q000502:physiology*; D019143:Evolution, Molecular; D007438:Introns / Q000235:genetics*; D008969:Molecular Sequence Data; D010802:Phylogeny; D012689:Sequence Homology, Nucleic Acid; D014404:Tubulin / Q000235:genetics*
D014404:Tubulin