Fulminant massive gas gangrene caused by Clostridium perfringens.
Clostridium perfringens (C.P) gas gangrene is one of the most fulminant infectious diseases. We encountered fulminant massive gas gangrene in a 56- year-old man with alcoholic liver cirrhosis. The patient died 14 hours after diagnosis of gas gangrene (54 hours after admission). Dramatic changes in abdominal CT imaging revealed development of a massive volume of gas in the intra-portal vein, retroperitoneum and abdominal subcutaneous tissue within 24 hours. We also proved C.P infection by immunohistological staining, leading to a diagnosis of C.P gas gangrene.
Kuroda
Shoji
S
Department of Internal Medicine, Miki Sanyo Hospital, Japan.
Okada
Yumi
Y
Mita
Masaki
M
Okamoto
Yasuo
Y
Kato
Hirotaka
H
Ueyama
Shigemitsu
S
Fujii
Ikuzo
I
Morita
Sumiharu
S
Yoshida
Yasuaki
Y
D034861:Abdominal Wall; D000208:Acute Disease; D000907:Antibodies, Bacterial / Q000276:immunology; D003016:Clostridium perfringens / Q000276:immunology / Q000302:isolation & purification; D003113:Colonoscopy; D018450:Disease Progression; D005738:Gas Gangrene / Q000150:complications / Q000175:diagnosis / Q000382:microbiology*; D006801:Humans; D007150:Immunohistochemistry; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications; D008297:Male; D008875:Middle Aged; D011169:Portal Vein; D012007:Rectum; D012187:Retroperitoneal Space; D014057:Tomography, X-Ray Computed
D000907:Antibodies, Bacterial