Ifosfamide encephalopathy: a case report.
The aim of this short communication is to discuss the mechanism, modality and treatment of ifosfamide encephalopathy. We present the case of a 52-year-old woman treated with this alkylating agent who developed severe neurotoxicity. It was resolved with administration of Methylene blue, abundant intravenous hydration and interruption of ifosfamide.
Pavarana
Michele
M
Department of Clinical and Experimental Medicine, Section of Medical Oncology, University of Verona, Italy. michepava@excite.com
Nortilli
Rolando
R
Valcamonico
Francesca
F
Romito
Silvia
S
Zanoni
Tiziano
T
Cetto
Gianluigi
G
D001927:Brain Diseases / Q000139:chemically induced* / Q000150:complications / Q000188:drug therapy / Q000628:therapy*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D012509:Sarcoma / Q000150:complications / Q000188:drug therapy
D007069:Ifosfamide