title: PIV measurements of flow in a centrifugal blood pump: time-varying flow.
abstract: Measurements of the time-varying flow in a centrifugal blood pump operating as a left ventricular assist device (LVAD) are presented. This includes changes in both the pump flow rate as a function of the left ventricle contraction and the interaction of the rotating impeller and fixed exit volute. When operating with a pulsing ventricle, the flow rate through the LVAD varies from 0-11 L/min during each cycle of the heartbeat. Phase-averaged measurements of mean velocity and some turbulence statistics within several regions of the pump, including the inlet, blade passage, exit volute, and diffuser, are reported at 20 phases of the cardiac cycle. The transient flow fields are compared to the constant flow rate condition that was reported previously in order to investigate the transient effects within the pump. It is shown that the quasi-steady assumption is a fair treatment of the time varying flow field in all regions of this representative pump, which greatly simplifies the comprehension and modeling of this flow field. The measurements are further interpreted to identify the effects that the transient nature of the flow field will have on blood damage. Although regions of recirculation and stagnant flow exist at some phases of the cardiac cycle, there is no location where flow is stagnant during the entire heartbeat.
authors.affiliation: Section of Evolution & Ecology, University of California, One Shields Avenue, Davis, CA 95616, USA. sday@alumni.virginia.edu
authors.forename: Steven W
authors.initials: SW
authors.lastname: Day
authors.forename: James C
authors.initials: JC
authors.lastname: McDaniel
mesh_terms: D000465:Algorithms; D001783:Blood Flow Velocity; D002498:Centrifugation / Q000295:instrumentation / Q000379:methods; D003198:Computer Simulation; D017076:Computer-Aided Design; D004867:Equipment Design; D019544:Equipment Failure Analysis / Q000379:methods*; D006353:Heart-Assist Devices; D006801:Humans; D017078:Laser-Doppler Flowmetry / Q000379:methods*; D008955:Models, Cardiovascular; D011475:Prosthesis Failure; D011673:Pulsatile Flow; D013997:Time Factors; D016276:Ventricular Function; D016277:Ventricular Function, Left