title: The first hetero-bifunctionalization of the secondary face of beta-cyclodextrin: selective and efficient conversion of the A-ring of a 2A,2B-disulfonate to 2A,3A-epoxymannoside.
abstract: The A-ring of 2(A),2(B)-O,O-di(mesitylenesulfonyl)-beta-cyclodextrin was converted to 2(A),3(A)-epoxymannoside without affecting the other sulfonylated residue, which affords the first approach to hetero-bifunctionalization at the secondary hydroxyl side of cyclodextrins.
authors.affiliation: Department of Molecular Medicinal Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Bunkyo-machi 1-14, Nagasaki 852-8521, Japan. fujita@net.nagasaki-u.ac.jp.
authors.forename: Makoto
authors.initials: M
authors.lastname: Fukudome
authors.forename: Yuji
authors.initials: Y
authors.lastname: Sugimoto
authors.forename: De-Qi
authors.initials: DQ
authors.lastname: Yuan
authors.forename: Kahee
authors.initials: K
authors.lastname: Fujita
mesh_terms: D008362:Mannosides / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D013451:Sulfonic Acids / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D008362:Mannosides; D013451:Sulfonic Acids; D047392:beta-Cyclodextrins; C031215:betadex