title: [The place of routine immediate non-invasive ventilation following pulmonary resection in preventing pulmonary complications in patients with COPD (POPVNI Trial)].
abstract: BACKGROUND
  Respiratory complications are common following pulmonary resection and cause a significant mortality. The use of non-invasive ventilation (NIV) in acute respiratory insufficiency (ARI) is now well recognised. The prophylactic use of NIV in the absence of ARI and/or hypercapnia may be equally justified for the physiological benefits expected in the post-operative period following pulmonary surgery. The aim of our study therefore is to evaluate the effectiveness of NIV in the prevention of pulmonary complications in the immediate post-operative care of patients with moderate and severe COPD.
  
  
  METHODS
  It will be a multicentre, prospective, randomised, parallel, open ended study of patients with moderate and severe COPD admitted to hospital for pulmonary resection.
  
  
  RESULTS
  To determine whether the setting up of NIV immediately post-operatively reduces the incidence of acute respiratory events (acute respiratory insufficiency) and to identify any sub-groups who receive greater benefit from NIV. This study should establish the place of NIV in the immediate post operative care following pulmonary resection.
authors.affiliation: Service de pneumologie et reanimation, Hôpital Hôtel Dieu, Paris, France. christine.lorut@htd.ap-hop-paris.fr
authors.forename: C
authors.initials: C
authors.lastname: Lorut
authors.forename: A
authors.initials: A
authors.lastname: Rabbat
authors.forename: G
authors.initials: G
authors.lastname: Chatelier
authors.forename: A
authors.initials: A
authors.lastname: Lefevre
authors.forename: N
authors.initials: N
authors.lastname: Roche
authors.forename: J F
authors.initials: JF
authors.lastname: Regnard
authors.forename: G
authors.initials: G
authors.lastname: Huchon
mesh_terms: D000328:Adult; D006801:Humans; D008171:Lung Diseases / Q000209:etiology / Q000517:prevention & control*; D011013:Pneumonectomy / Q000009:adverse effects*; D011182:Postoperative Care; D011446:Prospective Studies; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000628:therapy*; D012121:Respiration, Artificial; D012720:Severity of Illness Index; D013997:Time Factors