Laparoscopic aortic reinforcement and endovascular graft placement in swine: a new external wrap.
OBJECTIVE
To evaluate the feasibility, safety, and histological response of laparoscopic external aortic wrap implantation in conjunction with an endovascular stent/stent-graft placement in the infrarenal aorta in a porcine model.


METHODS
Seven swine underwent laparoscopic retroperitoneal placement of a custom-made Dacron fabric wrap placed around the infrarenal aorta to create a landing zone for an endovascularly placed aortic stent/stent-graft.


RESULTS
Technical success was achieved in all animals without any major complications. Follow-up ranged from 1 to 4 weeks. At necropsy, the external wraps were well incorporated into the adventitia, and the stents/stent-grafts were well incorporated into the intima. Small patches of medial necrosis of the aortic wall were observed in one animal in the stent model and in two animals in the stent-graft model. There was no transmural necrosis observed. CONCLUSIONS This adjunct technique, an external wrap around the infrarenal aorta combined with endovascular grafting, is feasible and deserves further studies into how it may be used to facilitate endovascular repair of aortic aneurysms.


CONCLUSIONS
We hypothesize that our new device could provide capability of altering the proximal neck morphology of abdominal aortic aneurysm and reinforcement to the aortic wall. This, in turn, could improve eligibility for endovascular aneurysm repair and prevent or treat type I endoleak and graft migration. Future investigations will involve evaluation of the long-term effect of the external aortic wrap on the integrity of the aortic wall in an animal model and testing the clinical usefulness of this new technique.
Kudo
Toshifumi
T
Gonda (Goldschmied) Vascular Center, University of California at Los Angeles 90095-6958, USA.
Kao
Kenneth K
KK
Nelson
Scott D
SD
Reil
Todd D
TD
Haas
Bradley T
BT
Ahn
Samuel S
SS
D000818:Animals; D001012:Aorta, Abdominal / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation; D005240:Feasibility Studies; D005260:Female; D010535:Laparoscopy; D023421:Models, Animal; D015607:Stents; D013552:Swine