title: Loss and reappearance of Rho(D) antigen on the red blood cells of an individual with acute myelogenous leukemia.
abstract: Complete loss of Rho(D) antigen from red blood cells (RBCs) of individuals with hematologic disorders, though not frequent, has been reported. This case reports the loss of D antigen on the RBCs of a patient with acute myelogenous leukemia and its reappearance when he was in remission. Loss of D antigen expression coincided with worsening clinical and cytogenetic disease. At the time of D antigen loss, the patient also had cytogenetic abnormalities in the bone marrow cells. When he was in remission, the chromosomal abnormalities were no longer detectable, and his RBCs regained D antigen expression.
authors.affiliation: Blood Bank, The Mount Sinai Medical Center, One Gustave Levy Place, New York, NY 10029, USA.
authors.forename: K
authors.initials: K
authors.lastname: Mohandas
authors.forename: V
authors.initials: V
authors.lastname: Najfield
authors.forename: H
authors.initials: H
authors.lastname: Gilbert
authors.forename: P
authors.initials: P
authors.lastname: Azar
authors.forename: D
authors.initials: D
authors.lastname: Skerrett