title: [Acute pancreatitis: surgical therapy].
abstract: Today, treatment of acute pancreatitis is mainly conservative and surgery is on the retreat. Infection of pancreatic necrosis is still the main risk factor of morbidity and mortality in the course of necrotizing disease. A prophylactic treatment with antibiotics can reduce both infectious complications and mortality. Thus, antibiotics should be administered in severe pancreatitis. If pancreatic infection is suspected, fine needle aspiration should be performed. Today, infected pancreatic necrosis is a well accepted indication for surgery. Aim of the surgical procedure is to remove the septic focus by debridement of the infected pancreatic and peripancreatic necrosis. The optimal timepoint for the surgical intervention is after the third week after onset of the disease. At that time, necrotic tissue is well demarcated. Therefore bleeding complications and removal of vital tissue can be avoided. Today, surgical procedures should combine the necrosectomy with a postoperative method to continuously remove necrosis and debris. This is the case with the following two techniques, the postoperative continuous lavage and the closed packing.
authors.affiliation: Abteilung für Aligemeine und Viszerale Chirurgie, Chirurgische Universitätsklinik Heidelberg.
authors.forename: J
authors.initials: J
authors.lastname: Werner
authors.forename: L
authors.initials: L
authors.lastname: Schneider
authors.forename: W
authors.initials: W
authors.lastname: Uhl
authors.forename: M W
authors.initials: MW
authors.lastname: Büchler
mesh_terms: D019072:Antibiotic Prophylaxis; D003646:Debridement; D004322:Drainage / Q000379:methods; D006801:Humans; D010179:Pancreas / Q000473:pathology / Q000601:surgery; D019283:Pancreatitis, Acute Necrotizing / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D010533:Peritoneal Lavage; D011182:Postoperative Care; D011379:Prognosis; D012086:Reoperation; D015996:Survival Rate