title: Chiral quantification of D-, L-phenylglycine mixture using mass spectrometric kinetic method.
abstract: A novel mass spectrometric method is applied to rapid, accurate, quantitative analysis of chiral phenylglycine. Transition-metal-bound complex ions containing the chiral phenylglycine are generated by electrospray ionization mass spectrometry and subjected to collision-induced dissociation. The ratio of the two competitive dissociation rates is related to the enantiomeric composition of the mixture, allowing the determination of enantiomeric contamination in the intermediates.
authors.affiliation: College of Chemistry, Institute of Miniature Analytical Instrumentation, Jilin Province Research Center for Engineering and Technology of Spectral Instruments, Jilin University, Changchun 130021, China.
authors.forename: Li
authors.initials: L
authors.lastname: Ming
authors.forename: Liu
authors.initials: L
authors.lastname: Zhiqiang
authors.forename: Chen
authors.initials: C
authors.lastname: Huanwen
authors.forename: Liu
authors.initials: L
authors.lastname: Shuying
authors.forename: Jin
authors.initials: J
authors.lastname: Qinhan
mesh_terms: D005998:Glycine / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry; D007700:Kinetics; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D013237:Stereoisomerism
chemical_list: C027797:phenylglycine chloride; D005998:Glycine