title: The spontaneous regression of tufted angioma. A case of regression after two recurrences and a review of 27 cases reported in the literature.
abstract: BACKGROUND
  Tufted angioma, a peculiar angioma that is characterized by tufts of capillary-sized vessels scattered 'cannonball fashion' within the dermis, is known, on occasion, to regress spontaneously. However, the appropriate waiting period for spontaneous regression has remained unclear.
  
  
  OBJECTIVE
  To know the appropriate waiting period for spontaneous regression of tufted angioma.
  
  
  METHODS
  We report here a case of tufted angioma that regressed spontaneously after the lesions had recurred twice. We also review previously reported cases of tufted angioma with spontaneous regression, including cases in the Japanese and non-Japanese literature.
  
  
  RESULTS
  In 18 (86%) of the 21 cases, the waiting period was more than 6 months and in 20 cases (95%) it was less than 2 years.
  
  
  CONCLUSIONS
  The appropriate wait for spontaneous regression might be between 6 months and 2 years.
authors.affiliation: Department of Anatomy, Biology and Medicine (Dermatology), Faculty of Medicine, Oita University, Oita-gun, Oita, Japan.
authors.forename: Kazushi
authors.initials: K
authors.lastname: Ishikawa
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Hatano
authors.forename: Hiroki
authors.initials: H
authors.lastname: Ichikawa
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Hashimoto
authors.forename: Sakuhei
authors.initials: S
authors.lastname: Fujiwara
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D005260:Female; D005500:Follow-Up Studies; D018324:Hemangioma, Capillary / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D007150:Immunohistochemistry; D009365:Neoplasm Regression, Spontaneous / Q000473:pathology*; D018570:Risk Assessment; D012720:Severity of Illness Index; D012878:Skin Neoplasms / Q000473:pathology* / Q000503:physiopathology