A successfully treated case of mycetoma due to Nocardia veterana.
We report a successfully treated case of mycetoma from which an unusual Nocardia species was isolated. The isolate was identified as N. veterana by biochemical characterization and 16S ribosomal RNA gene sequencing, and it has not been previously reported as a causative agent of human mycetomas. Treatment with various antibiotics over 6 years and surgical resection failed to cure the disease. However, the combination of intravenous imipenem/cilastatin and amikacin along with oral clarithromycin and minocycline proved very effective in this case. This is the first case report of mycetoma due to N. veterana in a clinical setting.
Kashima
M
M
Department of Dermatology, St Marianna University, Kawasaki, Kanagawa 216-8511, Japan. m2kashima@marianna-u.ac.jp
Kano
R
R
Mikami
Y
Y
Takahama
H
H
Ito
M
M
Hasegawa
A
A
Mizoguchi
M
M
D000328:Adult; D000583:Amikacin / Q000627:therapeutic use; D015377:Cilastatin / Q000627:therapeutic use; D017291:Clarithromycin / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use; D008911:Minocycline / Q000627:therapeutic use; D008271:Mycetoma / Q000188:drug therapy* / Q000382:microbiology; D009615:Nocardia / Q000302:isolation & purification / Q000472:pathogenicity; D009784:Occupational Diseases / Q000188:drug therapy* / Q000382:microbiology; D016896:Treatment Outcome
D015377:Cilastatin; D015378:Imipenem; D000583:Amikacin; D008911:Minocycline; D017291:Clarithromycin