title: Superior vena cava flutter: electrophysiology and ablation.
abstract: BACKGROUND
  Reentry within a major thoracic vein has been suggested as a cause of atrial arrhythmias. However, little is known about these potential reentrant circuits.
  
  
  RESULTS
  Atypical atrial flutter was induced and mapped in 67 out of 225 atrial flutter ablation procedures. Reentry around the superior vena cava (SVC) was suspected in three patients. The suspected SVC flutter was induced and terminated by pacing in all patients. Fusion was demonstrated during flutter entrainment by subeustachian isthmus pacing in all of them. The postpacing interval following entrainment by pacing from different sites of the right atrium (RA) or coronary sinus was longer than the flutter cycle length. Macroreentry within the SVC was demonstrated both by sequential activation and a postpacing interval matching the flutter cycle length when pacing from different sites around the SVC in all patients. Atrial-venous-atrial electrogram sequence was demonstrated following flutter entrainment by atrial pacing. Flutter was terminated by an electrical stimulus delivered to the SVC, which was not propagated to the trabeculated RA, in one patient, and linear radiofrequency application from the distal SVC to the posterior wall of the RA, or to the superoseptal portion of the crista terminalis, in the other two.
  
  
  CONCLUSIONS
  Macroreentry within the SVC is a distinctive mechanism responsible for rapid atrial activation, which is different from other reported flutter mechanisms, such as upper loop reentry. SVC longitudinal radiofrequency application can eliminate the arrhythmia without the need for complete electrical disconnection of the vein.
authors.affiliation: Laboratory of Cardiac Electrophysiology, Hospital La Paz, Universidad Autónoma, Madrid, Spain. jlmerino@secardiologia.es
authors.forename: Jose L
authors.initials: JL
authors.lastname: Merino
authors.forename: Rafael
authors.initials: R
authors.lastname: Peinado
authors.forename: Mauricio
authors.initials: M
authors.lastname: Abello
authors.forename: Mariana
authors.initials: M
authors.lastname: Gnoatto
authors.forename: Mar G
authors.initials: MG
authors.lastname: Vasserot
authors.forename: Jose A
authors.initials: JA
authors.lastname: Sobrino
mesh_terms: D000368:Aged; D001282:Atrial Flutter / Q000503:physiopathology / Q000601:surgery*; D002304:Cardiac Pacing, Artificial; D017115:Catheter Ablation; D022062:Electrophysiologic Techniques, Cardiac; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014683:Vena Cava, Superior / Q000503:physiopathology*