PDZ domains and the politics of polarity in lymphocytes.
In this issue of Immunity, Ludford-Menting at al. (2005) show that scaffold proteins previously implicated in the control of epithelial cell polarity also play an important role in determining the macroscopic organization of the engaged T cell.
Xavier
Ramnik
R
Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston 02114, USA.
Seed
Brian
B
D000818:Animals; D016764:Cell Polarity / Q000502:physiology*; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism*; D013601:T-Lymphocytes / Q000166:cytology*
D008565:Membrane Proteins