Two cases of amisulpride overdose: a cause for prolonged QT syndrome.
Two cases of deliberate self-poisoning with 5 g and 3.6 g of amisulpride, respectively, are reported. In both cases, QT prolongation and hypocalcaemia were noted. The QT prolongation appeared to respond to administration of i.v. calcium gluconate.
Ward
David Ian
DI
Department of Emergency Medicine, Nambour General Hospital, Nambour, Queensland, Australia. david_ward@health.qld.gov.au
D000328:Adult; D000077582:Amisulpride; D014150:Antipsychotic Agents / Q000009:adverse effects*; D002125:Calcium Gluconate / Q000008:administration & dosage; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000139:chemically induced / Q000188:drug therapy; D007262:Infusions, Intravenous; D008133:Long QT Syndrome / Q000139:chemically induced* / Q000188:drug therapy; D008297:Male; D013469:Sulpiride / Q000009:adverse effects / Q000031:analogs & derivatives*
D014150:Antipsychotic Agents; D013469:Sulpiride; D000077582:Amisulpride; D002125:Calcium Gluconate