Thyroid nodules: evaluation with power Doppler and duplex Doppler ultrasound.
This study purposes a new classification of thyroid nodules blood flow by power duplex Doppler ultrasound. A total of 177 nodules were studied with B-mode scanning, power Doppler, and spectral analysis. These data were compared with cytological results from ultrasound-guided fine-needle aspiration biopsy. Univariate and multivariate logistic regression analysis were performed. The power Doppler analysis of the nodules produced 5 vascular patterns: I, absence of signal blood flow; II, exclusively perinodular blood flow; III, perinodular >/= central blood flow; IV, central blood flow > perinodular blood flow; V, exclusively central blood flow. Statistical analysis revealed a significant relationship between these vascular patterns and cytological results. The spectral analysis demonstrated that the resistance index were higher in nodules with malignant versus other cytology ( P < 0.001). The results indicate that power duplex Doppler facilitates screening of thyroid nodules at high risk for malignancy with elevated sensitivity (92.3%) and specificity (88%).
Chammas
Maria Cristina
MC
Division of Ultrasound (Radiology Institute), University of São Paulo Medical School, Brazil. mcchammas@hotmail.com
Gerhard
Renê
R
de Oliveira
Ilka Regina Souza
IR
Widman
Azzo
A
de Barros
Nestor
N
Durazzo
Marcelo
M
Ferraz
Alberto
A
Cerri
Giovanni Guido
GG
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D002648:Child; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D012680:Sensitivity and Specificity; D016606:Thyroid Nodule / Q000098:blood supply / Q000000981:diagnostic imaging*; D018616:Ultrasonography, Doppler, Duplex; D014655:Vascular Resistance