Comparison of two over-the-counter tooth whitening products using a novel system.
Tooth whitening is one of the most widely accepted esthetic procedures in dentistry. Various treatment options include in-office and prescribed at-home bleaching procedures, over-the-counter bleaching kits, and whitening dentifrices. This study evaluated and compared a 6% hydrogen peroxide tooth bleaching gel delivered on polyethylene film (HP) with an 18% carbamide peroxide brush-applied liquid gel (CP). A total of 59 subjects completed this 2-week, examiner blind, randomized, parallel group study. Both treatments were applied twice daily for 2 weeks according to the manufacturer's instructions. Evaluations for oral safety and Vita tooth shade were conducted by a dental examiner at baseline and 2 weeks after product use. In addition, the ShadeVision System was used to determine changes in Vita shade and L*a*b* values. Based on both the examiner and ShadeVision System assessments, both treatments significantly improved tooth shade. Improvements in Vita tooth shade based on the adjusted mean for HP were 2.64 (P < 0.001) and 2.33 (P < 0.001) for the examiner and ShadeVision System assessments, respectively, compared with improvements of 1.04 (P = .004) and 0.42 (P = 0.029) for CP users, respectively. The difference between treatments was found to be significant for both the examiner (P = .005) and ShadeVision (P = .001) assessments. Findings from the L*a*b* data derived from the ShadeVision System were in agreement with Vita assessments, with significant differences for changes in L*, a*, and b* in favor of HP users (P = .001). In this study, the ShadeVision method of color analysis was relatively easy to use and demonstrated significant differences between 2 OTC whitening products using both Vitapan and L*a*b* means of assessment.
Cronin
Matthew J
MJ
New Institutional Service Co., Inc, Northfield, New Jersey, USA.
Charles
Christine A
CA
Zhao
Qian
Q
Dembling
Wayne Z
WZ
D000328:Adult; D000077463:Carbamide Peroxide; D003116:Color; D003124:Colorimetry; D004337:Drug Carriers; D004338:Drug Combinations; D005260:Female; D005500:Follow-Up Studies; D005782:Gels; D006801:Humans; D006861:Hydrogen Peroxide / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D004366:Nonprescription Drugs / Q000627:therapeutic use*; D016877:Oxidants / Q000008:administration & dosage / Q000627:therapeutic use*; D010545:Peroxides / Q000008:administration & dosage / Q000627:therapeutic use; D020959:Polyethylene; D012449:Safety; D016037:Single-Blind Method; D014070:Tooth / Q000473:pathology; D014073:Tooth Bleaching / Q000379:methods*; D016896:Treatment Outcome; D014508:Urea / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use
D004337:Drug Carriers; D004338:Drug Combinations; D005782:Gels; D004366:Nonprescription Drugs; D016877:Oxidants; D010545:Peroxides; D000077463:Carbamide Peroxide; D014508:Urea; D020959:Polyethylene; D006861:Hydrogen Peroxide