title: An example of anti-JMH with characteristics of a clinically significant antibody.
abstract: The authors studied an example of red cell anti-JMH (John Milton Hagen) that exhibited several characteristics of a possible clinically significant antibody able to cause red cell destruction in vivo. Strong serological reactivity, a positive monocyte monolayer assay, and immunoglobulin subclass determination as IgG3 all indicate possible ability to destroy red cells. A51Cr-labeled red cell survival study was not done as the patient did not require red cell transfusions but may be recommended for this patient if transfusions become necessary.
authors.affiliation: American Red Cross Blood Services, Great Lakes Region, 1800 East Grand Avenue, P.O. Box 30101, Lansing, MI 48909, USA.
authors.forename: J
authors.initials: J
authors.lastname: Geisland
authors.forename: M
authors.initials: M
authors.lastname: Corgan
authors.forename: B
authors.initials: B
authors.lastname: Hillard