title: Group B streptococcal soft tissue infections in non-pregnant adults.
abstract: Skin and soft tissue infections are the most common presentations of invasive Streptococcus agalactiae infections. This study reviewed 71 patients in a medical centre in southern Taiwan with S. agalactiae soft tissue infections. The mortality rate was 7%, and 11% of patients lost their extremities following extensive tissue necrosis. Critical illness and the presence of cutaneous ulceration heralded a fatal prognosis. Risk-factors for amputation of limbs included advanced age, cutaneous ulceration and polymicrobial infection. It was concluded that invasive S. agalactiae soft tissue infections, as with infections caused by Streptococcus pyogenes, can also lead to substantial morbidity and mortality in non-pregnant adults.
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, National Cheng Kung University Hospital, Tainin, Taiwan.
authors.forename: N-Y
authors.initials: NY
authors.lastname: Lee
authors.forename: J-J
authors.initials: JJ
authors.lastname: Yan
authors.forename: J-J
authors.initials: JJ
authors.lastname: Wu
authors.forename: H-C
authors.initials: HC
authors.lastname: Lee
authors.forename: K-H
authors.initials: KH
authors.lastname: Liu
authors.forename: W-C
authors.initials: WC
authors.lastname: Ko
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000671:Amputation, Surgical; D005121:Extremities / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012867:Skin / Q000473:pathology; D018461:Soft Tissue Infections / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality / Q000473:pathology; D013290:Streptococcal Infections / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality / Q000473:pathology; D013292:Streptococcus agalactiae / Q000302:isolation & purification* / Q000472:pathogenicity; D013624:Taiwan