title: Successful pregnancy of a patient with Balo's concentric sclerosis.
abstract: Balo's concentric sclerosis is a severe demyelinating disease with poor prognosis. To date, nothing is known about the effects of pregnancy on the course of Balo's disease. We describe here the first successful pregnancy of a patient with Balo's concentric sclerosis. Upon neurological worsenings during pregnancy, our patient was treated with high-dose methylprednisolone and plasma-exchange. Intravenous immunoglobulin and interferon-beta-1a were given postpartum. At the last follow-up visit 2.5 years after the delivery the patient had only minor residual symptoms.
authors.affiliation: Department of Neurology, Turku University Hospital, Turku, Finland. laura.airas@utu.fi
authors.forename: Laura
authors.initials: L
authors.lastname: Airas
authors.forename: Timo
authors.initials: T
authors.lastname: Kurki
authors.forename: Hanna
authors.initials: H
authors.lastname: Erjanti
authors.forename: Reijo J
authors.initials: RJ
authors.lastname: Marttila
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000188:drug therapy* / Q000473:pathology*; D005260:Female; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage*; D010951:Plasma Exchange; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone