title: [Feasibility study on a noninvasive measurement system for boron concentration.].
abstract: The kinematics of boron compounds in vivo is crucial to fully and safely utilize boron neutron capture therapy. In this paper, we proposed a prompt gamma-ray Compton scatter camera (PG-CSC), which can evaluate the 3-D kinematics of boron compounds without invasion. This PG-CSC combines a Compton camera with prompt gamma-ray analysis. The results of its design optimization and tests using simulations showed that one-hour-measurement was sufficient to evaluate a 3-D boron concentration distribution in a rat's brain with the resolution of 1 mm in FWHM.
authors.affiliation: Research Center for Nuclear Science and Technology, the University of Tokyo, 2-11-16, Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan. masayori@n.t.u-tokyo.ac.jp.
authors.forename: Masayori
authors.initials: M
authors.lastname: Ishikawa
authors.forename: Masahiko
authors.initials: M
authors.lastname: Hirasawa
authors.forename: Takehiro
authors.initials: T
authors.lastname: Tomitani
authors.forename: Hideo
authors.initials: H
authors.lastname: Murayama
authors.forename: Masaharu
authors.initials: M
authors.lastname: Hoshi
mesh_terms: D000818:Animals; D001895:Boron / Q000627:therapeutic use; D001896:Boron Compounds; D016754:Boron Neutron Capture Therapy; D005240:Feasibility Studies; D015902:Gamma Cameras; D009502:Neutrons
chemical_list: D001896:Boron Compounds; D001895:Boron