title: [Lupus nephritis].
abstract: Lupus nephritis is a serious complication of systemic lupus erythematodes. It is important to establish the correct diagnosis in order to initiate the optimal treatment for a specific patient. Early therapy will prevent organ damage which otherwise can dramatically increase morbidity and mortality. This article provides information about pathogenesis, manifestations, laboratory investigations, histopathology and treatment of lupus nephritis. Besides the indication for treatment the various immunosuppressive protocols are discussed. Moreover, a specific treatment option is proposed and the follow up is described.
authors.affiliation: Klinik für Transplantationsimmunologie und Nephrologie, Universitätsspital Basel. jsteiger@uhbs.ch
authors.forename: J
authors.initials: J
authors.lastname: Steiger
authors.forename: D
authors.initials: D
authors.lastname: Garzoni
authors.forename: M
authors.initials: M
authors.lastname: Mayr
mesh_terms: D002986:Clinical Trials as Topic; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008181:Lupus Nephritis / Q000145:classification / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D012720:Severity of Illness Index
chemical_list: D007166:Immunosuppressive Agents