title: Clinical Relevance of the vacA, iceA, cagA, and flaA genes of Helicobacter pylori strains isolated in Eastern Taiwan.
abstract: The genotypes of Helicobacter pylori flaA, cagA, vacA, and iceA were determined for DNA isolated from patients with chronic gastritis or peptic ulcer in eastern Taiwan. The vacA gene encoding the s1a subtype was found to predominate in peptic ulcer patients, and the iceA1 genotype was associated with chronic gastritis. cagA and flaA genes were not found to be associated with these types of disease.
authors.affiliation: Department of Surgery, Tzu Chi University, Hualien 970, Taiwan.
authors.forename: Chao-Chuan
authors.initials: CC
authors.lastname: Wu
authors.forename: Pai-Yu
authors.initials: PY
authors.lastname: Chou
authors.forename: Chi-Tan
authors.initials: CT
authors.lastname: Hu
authors.forename: Zuo-Chai
authors.initials: ZC
authors.lastname: Liu
authors.forename: Chih-Yung
authors.initials: CY
authors.lastname: Lin
authors.forename: Yi-Hsiung
authors.initials: YH
authors.lastname: Tseng
authors.forename: Nien-Tsung
authors.initials: NT
authors.lastname: Lin
mesh_terms: D000328:Adult; D000368:Aged; D000942:Antigens, Bacterial / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics*; D002908:Chronic Disease; D005260:Female; D005408:Flagellin / Q000235:genetics*; D005756:Gastritis / Q000382:microbiology; D005838:Genotype; D016481:Helicobacter Infections / Q000382:microbiology / Q000503:physiopathology*; D016480:Helicobacter pylori / Q000145:classification / Q000235:genetics / Q000472:pathogenicity*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000382:microbiology; D013624:Taiwan
chemical_list: D000942:Antigens, Bacterial; D001426:Bacterial Proteins; C074689:VacA protein, Helicobacter pylori; C080866:cagA protein, Helicobacter pylori; C405087:iceA1 protein, Helicobacter pylori; D005408:Flagellin; C067138:flaA protein, bacteria