title: The use of controlled-release versus scheduled oxycodone in the immediate postoperative period following total joint arthroplasty.
abstract: This prospective study examined whether better pain control could be achieved in the first 48 hours after joint arthroplasty with controlled-release oxycodone compared to scheduled oxycodone with acetaminophen. In the study group, controlled-release oxycodone was administered on the day of surgery and was continued during patients' hospital stay. The study group then was compared to a previous group in which effective pain control was obtained with around-the-clock oxycodone with acetaminophen. Findings indicated controlled-release oxycodone did not provide better pain control compared to scheduled oxycodone with acetaminophen in the first 48 hours following total joint arthroplasty.
authors.affiliation: Department of Orthopedics, Mount Carmel Health System, Columbus, OH 43222, USA.
authors.forename: James M
authors.initials: JM
authors.lastname: Kerpsack
authors.forename: Richard A
authors.initials: RA
authors.lastname: Fankhauser
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage*; D019644:Arthroplasty, Replacement, Hip; D003692:Delayed-Action Preparations; D006801:Humans; D010098:Oxycodone / Q000008:administration & dosage*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D011446:Prospective Studies
chemical_list: D000701:Analgesics, Opioid; D003692:Delayed-Action Preparations; D010098:Oxycodone