title: The impact of prostate size in laparoscopic radical prostatectomy.
abstract: OBJECTIVE
  Large prostates can be challenging to remove during open or laparoscopic radical prostatectomy (LRP). Our objective was to critically analyse the impact of prostate volume in LRP.
  
  
  METHODS
  400 cases of LRP were performed. Three hundred and fourteen patients had a small prostate (weight < 75 g) and 86 patients had a large prostate (weight > or = 75 g) on final histology. The following outcomes were assessed: operative time; estimated blood loss (EBL); transfusion rate; length of hospital stay (LOS); length of catheterisation; perioperative and postoperative complications (including incontinence and erectile dysfunction); surgical margin status; and early biochemical recurrence rates.
  
  
  RESULTS
  Patients' age, PSA, Gleason sum and clinical stage were all similar. Larger prostates were associated with a 14 minutes longer mean operating time (p < 0.001), but fewer positive surgical margins (p = 0.01). Blood loss, blood transfusion rate, length of hospital stay, length of catheterisation and complication rate were all similar in both groups.
  
  
  CONCLUSIONS
  Prostate size should not be a factor determining a patient's suitability for LRP. Further follow-up is needed to assess the effect of prostate size on long-term functional and oncological results.
authors.affiliation: Department of Urology, The North Hampshire Hospital, Aldermaston Road, Basingstoke, Hampshire RG24 9NA, England, UK. c.chang@doctor.com
authors.forename: C M
authors.initials: CM
authors.lastname: Chang
authors.forename: D
authors.initials: D
authors.lastname: Moon
authors.forename: T R
authors.initials: TR
authors.lastname: Gianduzzo
authors.forename: C G
authors.initials: CG
authors.lastname: Eden
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery*; D000328:Adult; D000368:Aged; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011467:Prostate / Q000473:pathology*; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery*; D016896:Treatment Outcome