title: Usefulness and influence of age of a novel rapid monoclonal enzyme immunoassay stool antigen for the diagnosis of Helicobacter pylori infection in children.
abstract: A novel rapid monoclonal enzyme immunoassay stool antigen for Helicobacter pylori detection (Immunocard STAT!HpSA, Meridian Diagnostic Inc , Cincinnati, OH) was evaluated in 29 infected and 99 noninfected children. The overall sensitivity, specificity, and positive and negative predictive values were 86.2%, 92.9%, 78.1%, and 95.8%, respectively, with an accuracy of 91.4%. The highest performance was observed in children older that 10 years, with a sensitivity level of 100%, contrasting with a lower level, 75%, in those younger than 5 years. A good negative predictive value was observed in all age groups, particularly in older children achieving 100%.
authors.affiliation: Department of Pediatrics-Neonatology, Hôpital Cochin-Saint Vincent de Paul, Université Paris V-René Descartes, 75674 Paris Cedex 14, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Kalach
authors.forename: Van Bang
authors.initials: VB
authors.lastname: Nguyen
authors.forename: Michel
authors.initials: M
authors.lastname: Bergeret
authors.forename: Névine
authors.initials: N
authors.lastname: Boutros
authors.forename: Christophe
authors.initials: C
authors.lastname: Dupont
authors.forename: Josette
authors.initials: J
authors.lastname: Raymond
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D005243:Feces / Q000382:microbiology; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000382:microbiology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods*; D007223:Infant; D008297:Male; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D013272:Stomach Diseases / Q000175:diagnosis / Q000382:microbiology*
chemical_list: D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial