title: [Study on the effect of qinggan jiangtang tablet in improving the insulin resistance in patients with multiple metabolic syndrome].
abstract: OBJECTIVE
  To observe the effect of Qinggan Jiangtang tablet (QJT) in improving the insulin resistance (IR) in patients with multiple metabolic syndrome (MMS).
  
  
  METHODS
  Adopting randomized controlled double-blinded method, 60 patients with MMS were divided equally into two groups. The treated group was treated by oral taking of QJT 3 tabs, twice a day and the control group treated by oral taking of Glucophage 3 tabs, twice a day, the therapeutic course for both groups was 1 month, and the observation lasted for 2 successive courses.
  
  
  RESULTS
  After treatment, levels of blood glucose, fasting and postprandial blood glucose, C-peptide and IR were significantly reduced with markedly improvement of beta-cell function in both groups, the difference between the two groups showed no significance. Change of plasma level of free fatty acids before and after treatment in both groups was insignificant.
  
  
  CONCLUSIONS
  QJT has the effects on reducing blood glucose, blood lipids, blood pressure and IR and improving function of beta cells.
authors.affiliation: Department of Endocrinology, the First Hospital Affiliated to Hunan College of TCM, Changsha. wyj5566@hotmail.com
authors.forename: Yan-juan
authors.initials: YJ
authors.lastname: Wang
authors.forename: Wen-feng
authors.initials: WF
authors.lastname: Zhu
authors.forename: Xing-kuan
authors.initials: XK
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007333:Insulin Resistance; D008297:Male; D024821:Metabolic Syndrome / Q000188:drug therapy*; D008687:Metformin / Q000627:therapeutic use; D008875:Middle Aged; D008517:Phytotherapy; D013607:Tablets
chemical_list: D004365:Drugs, Chinese Herbal; D007004:Hypoglycemic Agents; D013607:Tablets; D008687:Metformin