Molecular cloning of monkey histamine H4 receptor.
Histamine H(4) receptor is considered as a novel therapeutic target for allergic diseases. To enhance the knowledge about species difference, which is essential for drug discovery research, monkey H(4) receptor was identified. Monkey H(4) receptor was characterized to have comparable similarity with its human counterpart. Discovery of monkey H(4) receptor will contribute to a better interpretation of effective drug discovery.
Oda
Tamaki
T
Molecular Medicine Laboratories, Yamanouchi Pharmaceutical Co., Ltd., Ibaraki, Japan.
Matsumoto
Shun-ichiro
S
Matsumoto
Mitsuyuki
M
Takasaki
Jun
J
Kamohara
Masazumi
M
Soga
Takatoshi
T
Hiyama
Hideki
H
Kobori
Masato
M
Katoh
Masao
M
D000595:Amino Acid Sequence; D000818:Animals; D003001:Cloning, Molecular; D006801:Humans; D008252:Macaca fascicularis; D008969:Molecular Sequence Data; D043562:Receptors, G-Protein-Coupled / Q000737:chemistry / Q000235:genetics*; D011968:Receptors, Histamine / Q000737:chemistry / Q000235:genetics*; D000074040:Receptors, Histamine H4; D013045:Species Specificity
C418607:HRH4 protein, human; D043562:Receptors, G-Protein-Coupled; D011968:Receptors, Histamine; D000074040:Receptors, Histamine H4