title: Transfusion-related acute lung injury (TRALI).
abstract: A 50-year-old male presented for a Whipple's procedure to excise a pancreatic lesion. Massive transfusion of packed cells and fresh frozen plasma was required. Towards the end of the procedure, the patient developed sudden onset of frank pulmonary oedema and hypotension. A presumptive diagnosis of transfusion related lung injury was made after prompt investigations excluded circulatory overload or cardiogenic shock as the cause. This case report describes an increasingly common and life-threatening sequela of blood product transfusion, the management of which is complicated by the current lack of specific diagnostic tests.
authors.affiliation: Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Western Australia.
authors.forename: G
authors.initials: G
authors.lastname: Teague
authors.forename: A
authors.initials: A
authors.lastname: Hughes
authors.forename: D
authors.initials: D
authors.lastname: Gaylard
mesh_terms: D006801:Humans; D007022:Hypotension / Q000209:etiology*; D007431:Intraoperative Complications / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010949:Plasma; D011654:Pulmonary Edema / Q000209:etiology*; D012128:Respiratory Distress Syndrome / Q000209:etiology*; D065227:Transfusion Reaction