title: Prevalence of premature urinary luteinizing hormone surges in women with regular menstrual cycles and its effect on implantation of frozen-thawed embryos.
abstract: OBJECTIVE
  To determine the frequency and effect of premature luteinizing hormone (LH) surges on pregnancy rates in women with regular menstrual cycles.
  
  
  METHODS
  Retrospective cohort study.
  
  
  METHODS
  Assisted Reproductive Technology Program at private medical college.
  
  
  METHODS
  Regularly menstruating women undergoing frozen embryo transfer (ET).
  
  
  METHODS
  Detection of urinary LH surges with an RIA kit during natural-cycle frozen-embryos transfer.
  
  
  METHODS
  Incidence of premature LH surges and pregnancy outcomes.
  
  
  RESULTS
  Eighty-eight (46.8%) of 188 regularly menstruating women had premature LH surges and 33 (37%) of those 88 had multiple premature LH surges. Pregnancy rates per ET are similar between women with and without premature LH surges.
  
  
  CONCLUSIONS
  A high percentage of normally cycling women demonstrate premature urinary LH surges without an effect on outcome of frozen-thawed ETs.
authors.affiliation: Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA.
authors.forename: Stephan
authors.initials: S
authors.lastname: Krotz
authors.forename: Laurie J
authors.initials: LJ
authors.lastname: McKenzie
authors.forename: Pauline
authors.initials: P
authors.lastname: Cisneros
authors.forename: John
authors.initials: J
authors.lastname: Buster
authors.forename: Paula
authors.initials: P
authors.lastname: Amato
authors.forename: Sandra
authors.initials: S
authors.lastname: Carson
mesh_terms: D000328:Adult; D016009:Chi-Square Distribution; D015331:Cohort Studies; D015925:Cryopreservation / Q000706:statistics & numerical data*; D010064:Embryo Implantation / Q000502:physiology*; D005260:Female; D006801:Humans; D007986:Luteinizing Hormone / Q000652:urine*; D008597:Menstrual Cycle / Q000652:urine*; D008875:Middle Aged; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology; D015995:Prevalence; D012189:Retrospective Studies; D018709:Statistics, Nonparametric
chemical_list: D007986:Luteinizing Hormone