[Prevalence of HIV-1-infection in dialysis units in Spain and potential candidates for renal transplantation: results of a Spanish survey].
BACKGROUND
Patients with HIV infection and end-stage renal disease (ESRD) have improved their survival in the last few years. HIV infection is not considered a contradiction for renal transplantation, but little experience exists in renal transplantation in HIV infected individuals. There is no information about the prevalence of HIV infection in Spanish patients under renal replacement therapies (RRT).


METHODS
A survey was performed in Spanish dialysis units during 2004. The objective was to study the prevalence and characteristics of HIV infection in patients under RRT in Spain. We also aimed to know how many of them met the Spanish criteria to be included on the renal transplantation waiting list.


RESULTS
HIV prevalence was 1.15% (95%CI 0.85-1.45) of 4,962 patients who were under RRT, mostly under hemodialysis and, less commonly, peritoneal dialysis. The most frequent risk factor for HIV infection was parenteral drug use (58%). The most common causes of ESRD were glomerulonephritis (44%). The median time under RRT was 46 months. Coinfections with hepatitis C (60%) and B (7%) were found. Thirty-four percent of patients had a history of aids-defining events. Eighty-six percent were under HAART. The median CD4 cell count was 333 cells/.l and the viral load was undetectable in 68%. Of 40 patients with a completed clinical questionnaire, 9 (22.5%) met the Spanish criteria for renal transplantation.


CONCLUSIONS
HIV prevalence in patients under RRT in Spain is 1.15% (0.85%-1.45%) and 22.5% percent of these patients met the Spanish criteria to be included on a renal transplantation waiting list.
Barril
Guillermina
G
Servicio de Nefrología, Hospital Universitario La Princesa, Madrid, Spain. gbarril@wanadoo.es
Trullás
Juan-Carlos
JC
González-Parra
Emilio
E
Moreno
Asunción
A
Bergada
Eduardo
E
Jofre
Rosa
R
Martínez-Ara
Jorge
J
de Sequera
Patricia
P
Oliver
Jesús Angel
JA
Arrieta
Javier
J
Miró
José M
JM
D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D015897:Comorbidity; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology; D015528:HIV Seroprevalence; D015497:HIV-1; D006306:Health Surveys; D006436:Hemodialysis Units, Hospital / Q000706:statistics & numerical data*; D006509:Hepatitis B / Q000453:epidemiology; D006526:Hepatitis C / Q000453:epidemiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000601:surgery / Q000628:therapy; D016030:Kidney Transplantation; D008017:Life Expectancy; D018579:Patient Selection; D010530:Peritoneal Dialysis; D006435:Renal Dialysis; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D014019:Tissue Donors; D019562:Viral Load; D014850:Waiting Lists