Vogt-Koyanagi-Harada disease associated with interferon-A and ribavirin therapy for chronic hepatitis C infection.
A rare case of Vogt-Koyanagi-Harada disease associated with ribavirin and interferon-alpha treatment for chronic hepatitis C infection is presented. The potential role of interferon and/or ribavirin therapy is discussed. Physicians should be aware of the association between interferon-alpha and ribavirin use for hepatitis C infection and the development of Harada's disease. Close monitoring of such patients for ocular side effects is necessary.
Papastathopoulos
Konstantinos
K
Medical Retina Unit, First Department of Ophthalmology, Henry Dunant Hospital, 107 Mesogion Avenue, 11526 Athens, Greece.
Bouzas
Evridiki
E
Naoum
George
G
Vergados
Ioannis
I
Tsiodras
Sotirios
S
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D000998:Antiviral Agents / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D005451:Fluorescein Angiography; D019698:Hepatitis C, Chronic / Q000188:drug therapy*; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects* / Q000627:therapeutic use; D012163:Retinal Detachment / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D012254:Ribavirin / Q000009:adverse effects* / Q000627:therapeutic use; D016896:Treatment Outcome; D014607:Uveomeningoencephalitic Syndrome / Q000139:chemically induced* / Q000188:drug therapy
D000305:Adrenal Cortex Hormones; D000998:Antiviral Agents; D016898:Interferon-alpha; D012254:Ribavirin