title: Determination of antioxidants in cosmetics by micellar electrokinetic capillary chromatography with electrochemical detection.
abstract: A new and efficient method for the determination of antioxidants [Propyl gallate (PG), tert-butylhydroquinone (TBHQ), butylated hydroxyanisole (BHA), and butylated hydroxytoluene (BHT)] in cosmetics has been established by using micellar electrokinetic capillary chromatography with electrochemical detection (MECC-ED). Under the optimum conditions of the method, all analytes were successfully separated within 13 min at the separation voltage of 18 kV in a 20 mmol/L borate running buffer (pH 7.4) containing 25 mmol/L sodium dodecyl sulfate. The excellent linearity was obtained in the concentration range from 5.0 x 10(-4) to 2.0 x 10(-6) mol/L and the detection limits (S/N = 3) of PG, TBHQ, BHA, and BHT range from 3 x 10(-7) to 3 x 10(-6) mol/L.
authors.affiliation: Department of Chemistry, East China Normal University, Shanghai 200062, China.
authors.forename: Yueqing
authors.initials: Y
authors.lastname: Guan
authors.forename: Qingcui
authors.initials: Q
authors.lastname: Chu
authors.forename: Liang
authors.initials: L
authors.lastname: Fu
authors.forename: Jiannong
authors.initials: J
authors.lastname: Ye
mesh_terms: D000975:Antioxidants / Q000032:analysis*; D002083:Butylated Hydroxyanisole / Q000302:isolation & purification; D002084:Butylated Hydroxytoluene / Q000302:isolation & purification; D020374:Chromatography, Micellar Electrokinetic Capillary / Q000379:methods*; D003358:Cosmetics / Q000737:chemistry*; D004563:Electrochemistry; D006863:Hydrogen-Ion Concentration; D006873:Hydroquinones / Q000302:isolation & purification; D011435:Propyl Gallate / Q000302:isolation & purification; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012967:Sodium Dodecyl Sulfate
chemical_list: D000975:Antioxidants; D003358:Cosmetics; D006873:Hydroquinones; D002084:Butylated Hydroxytoluene; D002083:Butylated Hydroxyanisole; D012967:Sodium Dodecyl Sulfate; D011435:Propyl Gallate; C018855:2-tert-butylhydroquinone