title: Community-acquired pneumonia by Legionella pneumophila serogroups 1-6 in Brazil.
abstract: A prospective cohort study of adult patients hospitalized due to community-acquired pneumonia was carried out for 1 year in a Brazilian university general hospital to detect the incidence of community-acquired pneumonia by Legionella pneumophila serogroups 1-6. During a whole year, a total of 645 consecutive patients who were hospitalized due to a initial presumptive diagnosis of respiratory disease by ICD-10 (J00-J99), excluding upper respiratory diseases, were screened to detect the patients with community-acquired pneumonia. Fifty-nine consecutive patients hospitalized due to community-acquired pneumonia between July 19, 2000 and July 18, 2001, were included in the study. They had determinations of serum antibodies to L. pneumophila serogroups 1-6 by indirect immunofluorescence antibody test at the Infectious Diseases Laboratory of University of Louisville (KY, USA) and urinary antigen tests for L. pneumophila serogroup 1. Three patients had community-acquired pneumonia by L. pneumophila serogroups 1-6, two patients being diagnosed by seroconversion and positive urinary antigen tests; the other had negative serologies but strongly positive urinary antigen test. The incidence of community-acquired pneumonia by L. pneumophila serogroups 1-6 in our hospital was 5.1%.
authors.affiliation: Pulmonology Service, Hospital de Clínicas, Federal University of Rio Grande do Sul, Brazil. mariab@terra.com.br
authors.forename: Maria Bernadete F
authors.initials: MB
authors.lastname: Chedid
authors.forename: Darcy de O
authors.initials: Dde O
authors.lastname: Ilha
authors.forename: Marcio F
authors.initials: MF
authors.lastname: Chedid
authors.forename: Paulo R
authors.initials: PR
authors.lastname: Dalcin
authors.forename: Mary
authors.initials: M
authors.lastname: Buzzetti
authors.forename: Paulo
authors.initials: P
authors.lastname: Jaconi Saraiva
authors.forename: Daniela
authors.initials: D
authors.lastname: Griza
authors.forename: Sergio S
authors.initials: SS
authors.lastname: Menna Barreto
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000097:blood; D000942:Antigens, Bacterial / Q000652:urine; D001938:Brazil / Q000453:epidemiology; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology; D019084:Fluorescent Antibody Technique, Indirect; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D016952:Legionella pneumophila / Q000145:classification* / Q000276:immunology / Q000302:isolation & purification; D007877:Legionnaires' Disease / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000382:microbiology; D008875:Middle Aged; D018579:Patient Selection; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial