title: Transcatheter patch occlusion of perimembranous ventricular septal defects.
abstract: Sixteen surgical candidates for ventricular septal defect correction were brought to the catheterization laboratory for transcatheter patch occlusion. There were 3 cases of nonrestrictive ventricular septal defects, including 2 with malalignment (tetralogy of Fallot). All patients, except those with tetralogy of Fallot who were cyanotic, had large left-right shunts. They were all corrected through the femoral vein. All defects with the exception of 2 were successfully occluded (12 full occlusions, 2 residual shunts). On follow-up, there were no embolizations, aortic insufficiency, or other complications. The method appears effective and relatively safe, and could challenge the current surgical standard of treatment.
authors.affiliation: Athenian Institute of Pediatric Cardiology, Athens, Greece. terry@hol.gr
authors.forename: Eleftherios B
authors.initials: EB
authors.lastname: Sideris
authors.forename: Benjamin
authors.initials: B
authors.lastname: Macuil
authors.forename: Victor
authors.initials: V
authors.lastname: Varvarenko
authors.forename: Savvas
authors.initials: S
authors.lastname: Toumanides
mesh_terms: D000293:Adolescent; D000328:Adult; D001027:Aortography; D021721:Balloon Occlusion / Q000295:instrumentation*; D006328:Cardiac Catheterization; D002648:Child; D002675:Child, Preschool; D004452:Echocardiography; D004867:Equipment Design; D004869:Equipment Safety; D005500:Follow-Up Studies; D006345:Heart Septal Defects, Ventricular / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D011140:Polyurethanes; D016896:Treatment Outcome
chemical_list: D011140:Polyurethanes; C028279:polyurethane foam