Atypical serological response marked by a lack of detectable anti-gp43 antibodies in a patient with disseminated paracoccidioidomycosis.
Serological tests are frequently used to diagnosis paracoccidioidomycosis. A glycoprotein of 43 kDa is considered to be the main diagnostic antigen, being recognized by virtually all patients' sera. A case of atypical serological response, consisting of a lack of detectable anti-gp43 antibodies, in a patient with disseminated paracoccidioidomycosis is presented.
Vidal
Mônica S M
MS
Instituto de Medicina Tropical de São Paulo, Av. Dr. Enéas Carvalho de Aguiar, 500, andar térreo, CEP:05403-000, São Paulo, SP, Brazil. movida@usp.br.
Benard
Gil
G
de Brito
Thales
T
Dantas
Kátia C
KC
Pereira
Cristiane N
CN
França
Francisco O S
FO
da Silva
Ana M G
AM
Martins
José E C
JE
D000328:Adult; D000908:Antibodies, Fungal / Q000097:blood*; D000946:Antigens, Fungal / Q000276:immunology*; D005656:Fungal Proteins / Q000276:immunology*; D006023:Glycoproteins / Q000276:immunology*; D006801:Humans; D008297:Male; D010228:Paracoccidioides / Q000276:immunology*; D010229:Paracoccidioidomycosis / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology
C103180:43 kDa protein, Paracoccidioides; D000908:Antibodies, Fungal; D000946:Antigens, Fungal; D005656:Fungal Proteins; D006023:Glycoproteins