[Health-related quality of life after radical prostatectomy or radiotherapy].
OBJECTIVE
We compared general and disease specific health related quality of life (QOL) after surgery and radiotherapy for prostate cancer.


METHODS
We performed a retrospective survey of patients treated between 1992 and 2001. General and disease specific health related QOL were assessed by the SF-36 and the University of California-Los Angels Prostate Cancer Index (UCLA PCI). We mailed questionnaires of QOL survey and obtained from 143 and 73 men who treated surgery and radiotherapy. The median ages of surgery and radiation group were 70.9 and 79.2 years old, and the median periods after treatment were 2.7 and 2.0 years, respectively.


RESULTS
Physical function, role physical, social functioning and mental health were higher score in surgery group than radiation group, however, general health perceptions was higher in radiation group among SF-36. Surgery group had worse urinary function and better sexual function compared with radiation group. Multi-variable analysis showed that scores of social functioning, mental health and sexual function were most influenced by each modality, the scores of physical function, role physical, urinary function and sexual bother were most influenced by age, and the score of general health perceptions and body pain was most influenced by the existence of recurrence. CONSIDERATION: This cross-sectional survey cleared the differences of QOL after surgery and radiotherapy, and the influences of each modality. However, because of difference in background of each group, longitudinal investigation will need to aid patients in the decision making process.
Hashine
Katsuyoshi
K
Department of Urology, National Organization Shikoku Cancer Center, Matsuyama, Japan.
Numata
Kosaku
K
Koizumi
Takahiro
T
Azuma
Koji
K
Sumiyoshi
Yoshiteru
Y
D000368:Aged; D003131:Combined Modality Therapy; D003430:Cross-Sectional Studies; D006801:Humans; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000503:physiopathology / Q000532:radiotherapy* / Q000601:surgery*; D011788:Quality of Life; D012189:Retrospective Studies; D012725:Sexual Behavior / Q000502:physiology