Diffusion tensor imaging in lissencephaly.
Lissencephaly is a rare brain malformation characterized histologically by arrested neuronal migration such that the brain resembles that of a fetus before 23-24 weeks gestation. We studied a neonate with lissencephaly by using diffusion tensor imaging and suggest the dysplastic densely cellular layer IV is visible as a band of anisotropic diffusion. Fiber tracking showed lack of connectivity between the cortex and deep white matter and an abnormal limbic system.
Rollins
Nancy
N
Department of Radiology, Children's Medical Center, Dallas, TX 75235, USA.
Reyes
Tony
T
Chia
Jon
J
D001921:Brain / Q000002:abnormalities* / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male