title: Overactive bladder: treatment options for the aging woman.
abstract: Overactive bladder (OAB) is a common, chronic, and debilitating condition that is most often observed in the elderly population. It has a profound impact on the quality of life of patients, affecting many aspects of daily living, social interaction, and self-perception of health status. Possible neurological, muscular, and metabolic causes have been proposed, but in most cases the exact pathophysiology remains unclear. The management of OAB can be initiated conservatively with behavioral modification and antimuscarinics. For refractory cases, neuromodulation, denervation techniques, and bladder augmentation may be indicated. Not all patients are cured, but most may be improved with appropriate individualized therapy.
authors.affiliation: Department of Gynecology, Section of Urogynecology and Reconstructive Pelvic Surgery, Cleveland Clinic Florida, Weston, Florida 33331, USA.
authors.forename: Sun Hee
authors.initials: SH
authors.lastname: Park
authors.forename: G Willy
authors.initials: GW
authors.lastname: Davila
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000375:Aging; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D018680:Cholinergic Antagonists / Q000627:therapeutic use; D003888:Desensitization, Immunologic; D004599:Electric Stimulation Therapy; D005260:Female; D006304:Health Status; D006801:Humans; D008875:Middle Aged; D018727:Muscarinic Antagonists / Q000627:therapeutic use; D011788:Quality of Life; D011976:Receptors, Muscarinic / Q000627:therapeutic use; D012649:Self Concept; D014481:United States; D014549:Urinary Incontinence / Q000188:drug therapy / Q000517:prevention & control / Q000523:psychology* / Q000601:surgery / Q000628:therapy*
chemical_list: D000929:Antidepressive Agents, Tricyclic; D018680:Cholinergic Antagonists; D018727:Muscarinic Antagonists; D011976:Receptors, Muscarinic