Hereditary Melkersson-Rosenthal syndrome and multiple sclerosis.
The revision of MEDLINE from 1966 to 2003 did not report any association between multiple sclerosis (MS) and Melkersson-Rosenthal syndrome (MRS). This is a case report of a 51-year-old woman, with history of four recurrent Bell's palsies. In 1999 she developed a right facial paralysis due to a supranuclear pyramidal lesion with right monoparesis. The family history showed five relatives with recurrent Bell's paralysis and plicata tongue.


METHODS
right Bell's paralysis, left supranuclear facial paralysis, furrowed tongue, right hemiparesis with pallor of the optic disks. Brain magnetic resonance imaging (MRI) demonstrated the typical lesions of MS and CSF oligoclonal bands. This is the first observation of a patient with hereditary MRS and MS. The link between both diseases is discussed.
Cabrera-Gómez
J A
JA
International Center of Neurologic Restoration (CIREN), Avenida 25 #15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba. cabrera.gomez@infomed.sld.cu
Echazabal-Santana
N
N
Real-González
Y
Y
Romero García
K
K
Junior Sobrinho
Manuel
M
Gil Ocaña
M A
MA
González-Valdes
N
N
Valdes-Montesde Oca
M L
ML
Cristofo-Corominas
M
M
González de la Nuez
J
J
García Lahera
J
J
Ugarte Suárez
C
C
D005260:Female; D006801:Humans; D008556:Melkersson-Rosenthal Syndrome / Q000150:complications* / Q000235:genetics*; D008875:Middle Aged; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000150:complications* / Q000235:genetics*; D010375:Pedigree