Tacrolimus and posttransplant diabetes mellitus in renal transplantation.
The most prominent side effect of tacrolimus is the induction of posttransplant diabetes mellitus (PTDM). In this review, the authors discuss the incidence, mechanism, prevention, and treatment of tacrolimus-induced PTDM in renal patients.
van Hooff
Johannes P
JP
Department of Internal Medicine, University Hospital Maastricht, NL-6202 AZ Maastricht, The Netherlands. jho@sint.azm.nl
Christiaans
Maarten H L
MH
van Duijnhoven
Elly M
EM
D003924:Diabetes Mellitus, Type 2 / Q000139:chemically induced* / Q000453:epidemiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000276:immunology; D011183:Postoperative Complications / Q000139:chemically induced*; D012307:Risk Factors; D016559:Tacrolimus / Q000037:antagonists & inhibitors*
D007166:Immunosuppressive Agents; D016559:Tacrolimus