title: Surgical management of tuberculum sellae meningiomas: involvement of the optic canal and visual outcome.
abstract: OBJECTIVE
  To present a large series of surgically treated tuberculum sellae meningiomas with particular regard to involvement of the optic canal and visual outcome.
  
  
  METHODS
  A retrospective analysis was done on 53 patients (40 female) with meningiomas originating from the tuberculum sellae who underwent surgery between 1991 and 2002. The standard surgical approach consisted of pterional craniotomy. Sixteen meningiomas extended posteriorly onto the diaphragma sella, 29 anteriorly to the planum sphenoidale, and 19 to the anterior clinoid process. Thirty seven tumours involved the optic canal, three bilaterally. Follow up ranged from 6 to 108 months (mean 29.9 months).
  
  
  RESULTS
  Total macroscopic resection was achieved in 48 patients. Median tumour size was 2.6 cm. Postoperatively, visual acuity improved in 20 patients and deteriorated in seven. Preoperative and postoperative visual acuity worsened with increasing duration of preoperative symptoms and with increasing age. Extension into the intraconal space was a negative predictor. However, tumour size did not influence visual acuity. Recurrence occurred in two cases (21 and 69 months postoperatively). Two patients died from causes unrelated to the tumour.
  
  
  CONCLUSIONS
  In the majority of patients with tuberculum sellae meningiomas, total resection may be achieved through a pterional approach with minimal complications.
authors.affiliation: Clinic of Neurological Surgery, Wedau Kliniken, Zu den Rehwiesen 9, 47055 Duisburg, Germany. Uta_Schick@web.de
authors.forename: U
authors.initials: U
authors.lastname: Schick
authors.forename: W
authors.initials: W
authors.lastname: Hassler
mesh_terms: D000328:Adult; D000368:Aged; D015331:Cohort Studies; D003388:Cranial Fossa, Posterior / Q000601:surgery; D003399:Craniotomy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000601:surgery*; D008579:Meningioma / Q000175:diagnosis / Q000601:surgery*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000601:surgery; D009408:Nerve Compression Syndromes / Q000175:diagnosis / Q000601:surgery*; D009897:Optic Chiasm / Q000473:pathology / Q000601:surgery*; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology*; D011379:Prognosis; D012086:Reoperation; D012658:Sella Turcica / Q000601:surgery; D019291:Skull Base / Q000473:pathology / Q000601:surgery; D019292:Skull Base Neoplasms / Q000175:diagnosis / Q000601:surgery*; D013100:Sphenoid Bone / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014786:Vision Disorders / Q000175:diagnosis / Q000209:etiology*; D014792:Visual Acuity; D014794:Visual Fields