title: [The changes of bacteria group on oral mucosa after radiotherapy of postoperative patients of oral carcinoma].
abstract: OBJECTIVE
  To investigate the microbial contents presented on the surface of mucosa in the oral cavity of patients who accepted radiotherapy, and to provide the evidences of controlling post-radiotherapeutic infections.
  
  
  METHODS
  32 patients (19 males and 13 females) aged from 37 - 72 received radiotherapy after oral squamous cell carcinomas operation were selected. Samples of saliva were obtained from the radiated center and opposite mucosa before and after radiotherapy. The detective amount, detective ratio and constituent ratio were analysed by cultivation and identification.
  
  
  RESULTS
  Streptococci, Candida albicans and Pseudomonas aeruginosa significantly increased on both sides of the oral mucosa while Neisseria and Actinobacillus decreased on radiated region after the radiotherapy.
  
  
  CONCLUSIONS
  Radiotherapy has great effects on oral bacteria and pathogenic organism may play a role in post-radiotherapy infections. It is necessary to do bacteria culture and choose sensitive antibiotics regularly for post-radiotherapeutic patients.
authors.affiliation: Dept. of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: Kun
authors.initials: K
authors.lastname: Liu
authors.forename: Ning
authors.initials: N
authors.lastname: Gao
authors.forename: Yi-Chuan
authors.initials: YC
authors.lastname: Wang
authors.forename: Chang-Mei
authors.initials: CM
authors.lastname: Wang
authors.forename: Xiao-Yi
authors.initials: XY
authors.lastname: Wang
authors.forename: Qing-Hong
authors.initials: QH
authors.lastname: Gao
authors.forename: Ming
authors.initials: M
authors.lastname: Xuan
authors.forename: Yu-Ming
authors.initials: YM
authors.lastname: Wen
mesh_terms: D000900:Anti-Bacterial Agents; D001419:Bacteria / Q000302:isolation & purification*; D002176:Candida albicans / Q000302:isolation & purification; D002294:Carcinoma, Squamous Cell / Q000382:microbiology / Q000532:radiotherapy*; D006801:Humans; D009061:Mouth Mucosa / Q000382:microbiology*; D009062:Mouth Neoplasms / Q000382:microbiology / Q000532:radiotherapy*; D011184:Postoperative Period; D012463:Saliva
chemical_list: D000900:Anti-Bacterial Agents