title: Atypical serological response marked by a lack of detectable anti-gp43 antibodies in a patient with disseminated paracoccidioidomycosis.
abstract: Serological tests are frequently used to diagnosis paracoccidioidomycosis. A glycoprotein of 43 kDa is considered to be the main diagnostic antigen, being recognized by virtually all patients' sera. A case of atypical serological response, consisting of a lack of detectable anti-gp43 antibodies, in a patient with disseminated paracoccidioidomycosis is presented.
authors.affiliation: Instituto de Medicina Tropical de São Paulo, Av. Dr. Enéas Carvalho de Aguiar, 500, andar térreo, CEP:05403-000, São Paulo, SP, Brazil. movida@usp.br.
authors.forename: Mônica S M
authors.initials: MS
authors.lastname: Vidal
authors.forename: Gil
authors.initials: G
authors.lastname: Benard
authors.forename: Thales
authors.initials: T
authors.lastname: de Brito
authors.forename: Kátia C
authors.initials: KC
authors.lastname: Dantas
authors.forename: Cristiane N
authors.initials: CN
authors.lastname: Pereira
authors.forename: Francisco O S
authors.initials: FO
authors.lastname: França
authors.forename: Ana M G
authors.initials: AM
authors.lastname: da Silva
authors.forename: José E C
authors.initials: JE
authors.lastname: Martins
mesh_terms: D000328:Adult; D000908:Antibodies, Fungal / Q000097:blood*; D000946:Antigens, Fungal / Q000276:immunology*; D005656:Fungal Proteins / Q000276:immunology*; D006023:Glycoproteins / Q000276:immunology*; D006801:Humans; D008297:Male; D010228:Paracoccidioides / Q000276:immunology*; D010229:Paracoccidioidomycosis / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology
chemical_list: C103180:43 kDa protein, Paracoccidioides; D000908:Antibodies, Fungal; D000946:Antigens, Fungal; D005656:Fungal Proteins; D006023:Glycoproteins