title: [A case of arc welder's lung with ground-glass opacities and progressive massive fibrosis].
abstract: A 62-year-old man who had worked as a welder for 35 years was admitted with abnormal chest radiograph shadows. Chest CT scan showed ground-glass opacities (GGO) and nodular shadows (progressive massive fibrosis: PMF) with spiculation in both lung fields. Transbronchial lung biopsy (TBLB) findings of a nodule (left segment 8) revealed many iron particles in the alveoli and positive staining for Fe (Berlin blue stain). Moreover, bronchoalveolar lavage (BAL) fluid of a GGO (left segment 4) revealed many iron particles and positive staining for Fe (Berlin blue stain) in macrophages. Serum ferritin was extremely high (6.352 ng/ml) and ferritin in the BAL fluid was 210 ng/ml. Taking the clinical course and pathological findings together, pneumoconiosis (arc welder's lung) was diagnosed. The most common chest CT pattern in arc welder's lung is ill-defined micronodules diffusely distributed in the lung like hypersensitivity pneumonitis. Arc welder's lung rarely presents as PMF. We report a case of arc welder's lung accompanied with PMF.
authors.affiliation: First Department of Internal Medicine, Tokyo Medical University.
authors.forename: Tomohisa
authors.initials: T
authors.lastname: Yokoyama
authors.forename: Masahiro
authors.initials: M
authors.lastname: Aoshima
authors.forename: Eri
authors.initials: E
authors.lastname: Kurakawa
authors.forename: Park
authors.initials: P
authors.lastname: Jinho
authors.forename: Ikuma
authors.initials: I
authors.lastname: Kasuga
authors.forename: Kazunari
authors.initials: K
authors.lastname: Minemura
authors.forename: Kazuma
authors.initials: K
authors.lastname: Ohyashiki
mesh_terms: D005898:Glass; D006801:Humans; D008297:Male; D008875:Middle Aged; D011009:Pneumoconiosis / Q000000981:diagnostic imaging* / Q000473:pathology; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging* / Q000473:pathology; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed; D014896:Welding