[Hemodynamic reaction attended safety in severe head injury patients at different periods of operative treatment].
The safety of hemodynamic reactions were studied at the stages of operative treatment of patients with severe cranio-cerebral traumas (CCT) during anesthesia using alfa-2 adrenoagonist Clofelin and opioid analgetic Fentanyl and basal hypnotics Propofol and sodium Thiopental. It was shown that the using of these techniques of anesthesia in CCT patients is followed by a formation of a sufficient and physiologically justified level of neurovegetative stabilization. It facilitates a coordinated work of the mechanisms of auto-regulation of blood circulation responsible for the maintenance of stable tissue perfusion at all steps of operations.
Kondrat'ev
A  N
A
Paleĭ
D A
DA
D000700:Analgesics / Q000008:administration & dosage / Q000494:pharmacology; D019162:Anesthetics, Combined / Q000494:pharmacology*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage / Q000494:pharmacology*; D001775:Blood Circulation / Q000187:drug effects; D003000:Clonidine / Q000008:administration & dosage / Q000494:pharmacology; D006259:Craniocerebral Trauma / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D005283:Fentanyl / Q000008:administration & dosage / Q000494:pharmacology; D015600:Glasgow Coma Scale; D006439:Hemodynamics / Q000187:drug effects; D006706:Homeostasis; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000494:pharmacology; D015742:Propofol / Q000008:administration & dosage / Q000494:pharmacology; D013874:Thiopental / Q000008:administration & dosage / Q000494:pharmacology
D000700:Analgesics; D019162:Anesthetics, Combined; D018686:Anesthetics, Intravenous; D006993:Hypnotics and Sedatives; D013874:Thiopental; D003000:Clonidine; D005283:Fentanyl; D015742:Propofol