Axes formation and RNA localization.
Axes formation in flies and frogs largely depends on RNA localization pathways functioning in the oocytes. It is thought that motors moving along the cytoskeleton enable the selective transport of RNAs to different destinations during oocyte development. Many of the steps in RNA localization are conserved, despite the existence of a variety of mechanisms, including the formation of nuclear ribonucleoprotein complexes, and active transport along microtubules.
Minakhina
Svetlana
S
Waksman Institute, Department of Molecular Biology and Biochemistry, NJ Cancer Center, Rutgers University, 190 Frelinghuysen Road, Piscataway, NJ 08854-8020, USA.
Steward
Ruth
R
D000818:Animals; D019521:Body Patterning / Q000502:physiology*; D016764:Cell Polarity / Q000502:physiology; D005260:Female; D009865:Oocytes / Q000166:cytology / Q000502:physiology; D011485:Protein Binding; D012313:RNA / Q000235:genetics / Q000378:metabolism*; D016601:RNA-Binding Proteins / Q000378:metabolism
D016601:RNA-Binding Proteins; D012313:RNA