Variation among pathologists in histologic grading of canine cutaneous mast cell tumors.
Ten veterinary pathologists at 1 veterinary institution independently assigned histologic grades to the same 60 canine cutaneous mast cell tumors (MCTs). There was significant variation among pathologists in grading the MCTs (P < 0.001). The probability of assigning a low grade was significantly higher for the pathologists in this study who use a published reference for histologic grading of canine cutaneous MCTs that allows subcutaneous MCTs or MCTs with mitotic figures to be included in the low-grade category (P < 0.0001 and P < 0.0001, respectively).
Northrup
Nicole C
NC
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
Harmon
Barry G
BG
Gieger
Tracy L
TL
Brown
Cathy A
CA
Carmichael
K Paige
KP
Garcia
Anapatricia
A
Latimer
Kenneth S
KS
Munday
John S
JS
Rakich
Pauline M
PM
Richey
Lauren J
LJ
Stedman
Nancy L
NL
Cheng
An-Lin
AL
Howerth
Elizabeth W
EW
D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D012515:Mast-Cell Sarcoma / Q000473:pathology / Q000662:veterinary*; D015588:Observer Variation; D010341:Pathology, Veterinary / Q000592:standards; D012878:Skin Neoplasms / Q000473:pathology / Q000662:veterinary*