Comparison of pregnancy course and outcome with color and radiographic angiography of the placenta in a monochorionic triplet pregnancy.
A patient with spontaneous monochorionic (MC) triamniotic triplet pregnancy developed symptoms of feto-fetal-transfusion-syndrome (FFTS) at 18 weeks of gestation with one donor (oligohydramnios) and one receptor (polyhydramnios) triplet. The patient "received" a diet enriched with proteins. Amniotic-fluid volume returned to normal after 24 weeks. At 32 weeks, a Cesarean section was performed due to intra-uterine growth restriction of the donor triplet. Post partum color injection and computer angiograms showed arterio-arterial (AA) anastomoses between all triplets. Deep arterio-venous (AV) anastomoses between the two triplets who had demonstrated with oligo- and polyhydramnios between 18 and 26 weeks were revealed by computer angiography that were not seen by placental color angiogram. Detailed analysis of placental vascular communications by use of color injection angiogram of the chorionic plate and computer angiogram demonstrating deep anastomoses beneath the chorionic plate helps to understand the individual pathophysiology and clinical course in patients with FFTS, which is even more complex in MC triplet compared to MC twin pregnancies.
Kruse
A-J
AJ
Department of Perinatology, Isala Clinics (Sophia), Dr. v. Heesweg 2, NL-8025 AD, Zwolle, The Netherlands.
Havenith
M
M
Arabin
B
B
D000328:Adult; D000792:Angiography / Q000379:methods*; D001163:Arteriovenous Anastomosis / Q000473:pathology; D002823:Chorion / Q000196:embryology; D005260:Female; D005330:Fetofetal Transfusion / Q000473:pathology*; D006801:Humans; D010920:Placenta / Q000000981:diagnostic imaging / Q000473:pathology / Q000502:physiology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D014310:Triplets / Q000502:physiology*