Molecular diagnosis of lymphogranuloma venereum in patients with genital ulcer disease.
The detection of herpes, chancroid, and syphilis in genital ulcers is done by PCR. This is not so for lymphogranuloma venereum (LGV). We report on the use of a PCR with digestion that differentiates the LGV biovar from the trachoma biovar. Our findings suggest that the clinical description of LGV in current textbooks is incomplete.
Sturm
Patrick D J
PD
Genital Ulcer Disease Research Unit of the University of KwaZuluNatal, Durban, South Africa. sturm@kznu.ac.za
Moodley
Prashini
P
Govender
Keshnie
K
Bohlken
Louise
L
Vanmali
Trusha
T
Sturm
A Willem
AW
D000293:Adolescent; D000328:Adult; D002692:Chlamydia trachomatis / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D005260:Female; D005831:Genital Diseases, Female / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D005832:Genital Diseases, Male / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D008219:Lymphogranuloma Venereum / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D008297:Male; D016133:Polymerase Chain Reaction / Q000379:methods*; D014456:Ulcer / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology