[Necessity of prophylactic antibiotics in patients with primary liver cancer undergoing transcatheter arterial chemoembolization: a prospective study].
OBJECTIVE
To investigate the necessity of prophylactic administration of antibiotic in patients with primary liver cancer undergoing transcatheter arterial chemoembolization (TACE).


METHODS
Sixty patients without preoperative infection were randomized into two groups to receive a single dose of cefazolin (PA group) prior to TACE or no prophylactic antibiotics (NONE group). The incidence of postoperative infection was compared.


RESULTS
The incidence of postoperative infection was 3.4% (1/29) in NONE group and 3.2% (1/31) in PA group, without significant difference between the two groups (P>0.05).


CONCLUSIONS
Prophylactic antibiotics are not necessary for patients with primary liver cancer prior to TACE.
Wang
Jiang-yun
JY
Department of Interventional Therapy, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Chen
Yong
Y
Lu
Wei
W
Wei
Chuan-jun
CJ
D000328:Adult; D000368:Aged; D019072:Antibiotic Prophylaxis; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D002406:Catheterization, Peripheral; D002437:Cefazolin / Q000627:therapeutic use*; D016461:Chemoembolization, Therapeutic / Q000379:methods; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
D002437:Cefazolin