title: [Vertebral compression fractures--the first manifestations of acute lymphoblastic leukemia of childhood].
abstract: We report 6 children, aged 4.5- 16 years, with acute lymphoblastic leukaemia with back pain, exacerbated by walking as the first symptom of disease. Collapse of the vertebral bodies at multiple levels was shown on imaging. The presented group had good prognosis. In densitometric examination of BMD (bone mineral density) was observed loss in the thoracic and lumbar vertebrae in 5 out of 6 children. Chemotherapy resulted in decrease of pain and spontaneous remodelling of the vertebrae.
authors.affiliation: Klinika Onkologii Dzieciecej, Akademia Medyczna, ul. Waszyngtona 17, 15-274 Białystok, Poland. KMRoslan@amb.ac.bialystok.pl
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Muszynska-Roslan
authors.forename: Maryna
authors.initials: M
authors.lastname: Krawczuk-Rybak
authors.forename: Irena
authors.initials: I
authors.lastname: Krasowska
authors.forename: Jerzy
authors.initials: J
authors.lastname: Konstantynowicz
authors.forename: Wlodzimierz
authors.initials: W
authors.lastname: Luczynski
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000627:therapeutic use; D015519:Bone Density / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D005260:Female; D005598:Fractures, Spontaneous / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000188:drug therapy; D011859:Radiography; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents