title: Chronic Staphylococcus aureus infection leading to pyogenic granuloma and preventing socket re-epithelialization after orbital exenteration.
abstract: A 71-year-old woman underwent extenteration for conjunctival melanoma with orbital invasion. Her socket failed to epithelialize and contained a diffuse pyogenic granuloma that was caused by chronic Staphylococcus aureus infection. Extensive debridement and long-term intravenous antibiotics resulted in normal healing.
authors.affiliation: Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.
authors.forename: Mark P
authors.initials: MP
authors.lastname: Hatton
authors.forename: Marlene L
authors.initials: ML
authors.lastname: Durand
authors.forename: Peter A D
authors.initials: PA
authors.lastname: Rubin
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002908:Chronic Disease; D003131:Combined Modality Therapy; D003230:Conjunctival Neoplasms / Q000601:surgery; D003646:Debridement; D004847:Epithelial Cells / Q000473:pathology; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D005260:Female; D017789:Granuloma, Pyogenic / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D008545:Melanoma / Q000601:surgery; D009254:Nafcillin / Q000627:therapeutic use; D009361:Neoplasm Invasiveness; D017233:Orbit Evisceration; D009916:Orbital Diseases / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D011183:Postoperative Complications; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D014057:Tomography, X-Ray Computed; D014945:Wound Healing
chemical_list: D000900:Anti-Bacterial Agents; D009254:Nafcillin