DNA-BAR: distinguisher selection for DNA barcoding.
DNA-BAR is a software package for selecting DNA probes (henceforth referred to as distinguishers) that can be used in genomic-based identification of microorganisms. Given the genomic sequences of the microorganisms, DNA-BAR finds a near-minimum number of distinguishers yielding a distinct hybridization pattern for each microorganism. Selected distinguishers satisfy user specified bounds on length, melting temperature and GC content, as well as redundancy and cross-hybridization constraints.
DasGupta
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B
Department of Computer Science, University of Illinois at Chicago, Chicago, IL 60607-7053, USA.
Konwar
K M
KM
Mandoiu
I I
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Shvartsman
A A
AA
D000465:Algorithms; D002874:Chromosome Mapping / Q000379:methods*; D004247:DNA / Q000737:chemistry* / Q000235:genetics*; D017403:In Situ Hybridization / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software
D004247:DNA