[Clinical analysis of proteinuria and glomerular lesions in Henoch-Schönlein purpura nephritis of adults].
OBJECTIVE
To analyze the characteristics of proteinuria and glomerular lesions in Henoch-Schönlein purpura nephritis (HSPN) of adults.


METHODS
The pathologic results and clinical data of 103 HSPN patients were analyzed.


RESULTS
Patients with mild or moderate proteinuria accounted for 40.8% and 37.9%, respectively. Patients with nephropathic proteinuria accounted for about 21.4%. Severer proteinuria resulted in higher blood pressure and increased cholesterol, and albumin decreased gradually (P < 0.01); meanwhile, total glomerular lesion, tubulointerstitial lesion, and vascular lesion also became severer (P < 0.01).


CONCLUSIONS
Proteinuria may indirectly reflect the severity of glomerular lesions in HSPN of adults.
Liu
Dong-yan
DY
Department of Nephrology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
Wen
Yu-bing
YB
Li
Hang
H
Li
Xue-wang
XW
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005922:Glomerulonephritis, IGA / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications* / Q000473:pathology; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007678:Kidney Glomerulus / Q000473:pathology; D007684:Kidney Tubules / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009393:Nephritis / Q000175:diagnosis* / Q000209:etiology; D011507:Proteinuria / Q000209:etiology / Q000652:urine; D012189:Retrospective Studies
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M