Catalytic enantioselective allylation of ketones via a chiral indium(III) complex.
[reaction: see text] A chiral indium complex has been discovered to effect high enantioselectivities in the addition of allyltributylstannanes to ketones. The allylation of a variety of aromatic, alpha,beta-unsaturated and aliphatic ketones resulted in good yields and high enantioselectivities (up to 92% ee).
Teo
Yong-Chua
YC
Department of Chemistry, 3 Science Drive, National University of Singapore, Singapore 117543.
Goh
Joshua-Daniel
JD
Loh
Teck-Peng
TP