Carbonate-containing hydroxyapatite derived from calcium tripolyphosphate gel with urea.
Carbonate containing hydroxyapatite (CO3HAp) is one of the candidate materials as a bioresorbable bone substitute. In the present work, CO3HAp was efficiently prepared by a hydrothermal treatment of calcium tripolyphosphate gel with urea at 140 degrees C for 24 h. Chemical potential plots of the CO3HAp for estimation of its dissolution behavior suggested that the CO3HAp is more soluble than hydroxyapatite (HAp) and is as soluble as octacalcium phosphate (OCP) and/or beta -tricalcium phosphate (TCP). This material is expected to be applied to bioresorbable materials such as bone fillers.
Mizutani
Y
Y
R&D Center, NGK Spark Plug Co., Ltd., 2808 Iwasaki, Komaki, Aichi, 485-8510, Japan. yo-mizutani@mg.ngkntk.co.jp
Hattori
M
M
Okuyama
M
M
Kasuga
T
T
Nogami
M
M
D020341:Absorbable Implants; D001672:Biocompatible Materials / Q000032:analysis / Q000737:chemistry; D018786:Bone Substitutes / Q000032:analysis / Q000737:chemistry*; D002254:Carbonates / Q000737:chemistry*; D003460:Crystallization / Q000379:methods*; D017886:Durapatite / Q000032:analysis / Q000737:chemistry*; D005782:Gels / Q000737:chemistry; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D008422:Materials Testing; D010316:Particle Size; D011122:Polyphosphates / Q000032:analysis / Q000737:chemistry*; D012995:Solubility; D013499:Surface Properties; D014508:Urea / Q000032:analysis / Q000737:chemistry*
D001672:Biocompatible Materials; D018786:Bone Substitutes; D002254:Carbonates; D005782:Gels; D011122:Polyphosphates; D014508:Urea; D017886:Durapatite; C009293:trimetaphosphoric acid