DMC: novel celecoxib derivatives to rap cancer.
Dent
Paul
P
Department of Biochemistry, Virginia Commonwealth University, Massey Cancer Center, Richmond, VA 23298, USA. pdent@hsc.vcu.edu
Yacoub
Adly
A
Grant
Steven
S
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D000068579:Celecoxib; D018797:Cell Cycle Proteins / Q000032:analysis / Q000378:metabolism; D049109:Cell Proliferation / Q000187:drug effects; D019925:Cyclin A / Q000378:metabolism; D019926:Cyclin B / Q000378:metabolism; D050760:Cyclin-Dependent Kinase Inhibitor p27 / Q000378:metabolism; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology; D051379:Mice; D008819:Mice, Nude; D019950:Mitogen-Activated Protein Kinase 1 / Q000378:metabolism; D048052:Mitogen-Activated Protein Kinase 3 / Q000378:metabolism; D009368:Neoplasm Transplantation; D010766:Phosphorylation / Q000187:drug effects; D011720:Pyrazoles / Q000494:pharmacology*; D013449:Sulfonamides / Q000494:pharmacology*; D014183:Transplantation, Heterologous; D023041:Xenograft Model Antitumor Assays
C506698:2,5-dimethylcelecoxib; D000970:Antineoplastic Agents; D018797:Cell Cycle Proteins; D019925:Cyclin A; D019926:Cyclin B; D016861:Cyclooxygenase Inhibitors; D011720:Pyrazoles; D013449:Sulfonamides; D050760:Cyclin-Dependent Kinase Inhibitor p27; D019950:Mitogen-Activated Protein Kinase 1; D048052:Mitogen-Activated Protein Kinase 3; D000068579:Celecoxib