title: Fulminant massive gas gangrene caused by Clostridium perfringens.
abstract: Clostridium perfringens (C.P) gas gangrene is one of the most fulminant infectious diseases. We encountered fulminant massive gas gangrene in a 56- year-old man with alcoholic liver cirrhosis. The patient died 14 hours after diagnosis of gas gangrene (54 hours after admission). Dramatic changes in abdominal CT imaging revealed development of a massive volume of gas in the intra-portal vein, retroperitoneum and abdominal subcutaneous tissue within 24 hours. We also proved C.P infection by immunohistological staining, leading to a diagnosis of C.P gas gangrene.
authors.affiliation: Department of Internal Medicine, Miki Sanyo Hospital, Japan.
authors.forename: Shoji
authors.initials: S
authors.lastname: Kuroda
authors.forename: Yumi
authors.initials: Y
authors.lastname: Okada
authors.forename: Masaki
authors.initials: M
authors.lastname: Mita
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Okamoto
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Kato
authors.forename: Shigemitsu
authors.initials: S
authors.lastname: Ueyama
authors.forename: Ikuzo
authors.initials: I
authors.lastname: Fujii
authors.forename: Sumiharu
authors.initials: S
authors.lastname: Morita
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Yoshida
mesh_terms: D034861:Abdominal Wall; D000208:Acute Disease; D000907:Antibodies, Bacterial / Q000276:immunology; D003016:Clostridium perfringens / Q000276:immunology / Q000302:isolation & purification; D003113:Colonoscopy; D018450:Disease Progression; D005738:Gas Gangrene / Q000150:complications / Q000175:diagnosis / Q000382:microbiology*; D006801:Humans; D007150:Immunohistochemistry; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications; D008297:Male; D008875:Middle Aged; D011169:Portal Vein; D012007:Rectum; D012187:Retroperitoneal Space; D014057:Tomography, X-Ray Computed
chemical_list: D000907:Antibodies, Bacterial