title: [The distribution of fimA genotype of Porphyromonas gingivalis in chronic periodontitis patients].
abstract: OBJECTIVE
  To investigate the distribution of fimA genotype of P. gingivalis in chronic periodontitis patients.
  
  
  METHODS
  Subgingival plaque samples were collected from 101 chronic periodontitis patients. P. gingivalis was detected by both culture method and P. gingivalis 16S rRNA PCR. fimA type-specific primer were designed, and the distribution of fimA genotype of P. gingivalis in periodontitis patients were detected by PCR.
  
  
  RESULTS
  The detective ratio of P. gingivalis was 88.1%. Among them, a single fimA genotype was detected in most subgingival plaque samples (65.1%), and the distribution of five fimA genotypes among P. gingivalis positive patients was as follows: type I, 24.7%; type II, 43.8%; type III, 15.7%; type IV, 40.4%; type V, 3.4%; respectively.
  
  
  CONCLUSIONS
  P. gingivalis with various fimA genotypes were present in subgingival plaque samples from chronic periodontitis patients, and P. gingivalis with type II fimA and IV fimA were more predominant in chronic periodontitis patients, and they may be associated with the development of periodontitis.
authors.affiliation: Key Lab. of Oral Biomedical Engineering of Ministry of Education, Sichuan University, Chengdu 610041, China.
authors.forename: Yong-Hua
authors.initials: YH
authors.lastname: Guo
authors.forename: Ya-Fei
authors.initials: YF
authors.lastname: Wu
authors.forename: Tian-Jia
authors.initials: TJ
authors.lastname: Liu
authors.forename: Xiao-Rong
authors.initials: XR
authors.lastname: Xiao
authors.forename: Bin
authors.initials: B
authors.lastname: Zhou
authors.forename: Xue-Ping
authors.initials: XP
authors.lastname: Zhou
mesh_terms: D000328:Adult; D055113:Chronic Periodontitis / Q000382:microbiology*; D003773:Dental Plaque; D005260:Female; D036781:Fimbriae Proteins / Q000235:genetics*; D005838:Genotype; D006801:Humans; D008297:Male; D010518:Periodontitis; D016133:Polymerase Chain Reaction; D016966:Porphyromonas gingivalis / Q000235:genetics*
chemical_list: C063055:fimbrillin; D036781:Fimbriae Proteins