Anabolic steroid abuse: physiological and anaesthetic considerations.
This review summarises the physiological and pharmacological effects of the anabolic steroids used to enhance performance in sports. The anabolic steroids promote muscle growth and protein synthesis. Side-effects of anabolic steroids include cardiomyopathy, atherosclerosis, hypercoagulopathy, hepatic dysfunction, and psychiatric and behavioural disturbances. It is therefore appropriate that the anaesthetist be familiar with the abuse of anabolic steroids, their potential adverse effects, and the peri-operative risk associated with the use of these drugs.
Kam
P C A
PC
University of New South Wales, Department of Anaesthesia, St George Hospital, Kogarah, NSW 2217, Australia. p.kam@unsw.edu.au
Yarrow
M
M
D045930:Anabolic Agents / Q000494:pharmacology / Q000633:toxicity*; D000758:Anesthesia / Q000379:methods*; D002318:Cardiovascular Diseases / Q000139:chemically induced; D004300:Doping in Sports; D004347:Drug Interactions; D006801:Humans; D019966:Substance-Related Disorders / Q000150:complications / Q000503:physiopathology*
D045930:Anabolic Agents