title: [Adjacent segment disease after spine fusion and instrumentation].
abstract: Spinal instrumentation is a common method for the treatment of spinal disorders, but it can lead to the changes of spine biomechanics. Because of the stress changes, accelerated degeneration of the adjacent segment may occur as time goes by, namely adjacent segment disease. The accelerated degeneration can lead to secondary spinal stenosis, articulated joint degeneration, acquired spondylolisthesis, and spine instability, and some patients may have to receive surgery again. In recent years, the researchers gradually recognized the importance of this disease, and began to investigate its pathogenesis and management.
authors.affiliation: Department of Orthopaedic Surgery, PUMC Hospital, CAMS and PUMC, Beijing 100730, China. qiugx@medmail.com.cn
authors.forename: Gui-xing
authors.initials: GX
authors.lastname: Qiu
authors.forename: Hong-guang
authors.initials: HG
authors.lastname: Xu
authors.forename: Xi-sheng
authors.initials: XS
authors.lastname: Weng
mesh_terms: D006801:Humans; D007593:Joint Instability / Q000209:etiology* / Q000517:prevention & control; D011183:Postoperative Complications / Q000175:diagnosis / Q000517:prevention & control; D013122:Spinal Diseases / Q000601:surgery*; D013123:Spinal Fusion / Q000009:adverse effects* / Q000295:instrumentation; D013130:Spinal Stenosis / Q000209:etiology* / Q000517:prevention & control; D013168:Spondylolisthesis / Q000209:etiology* / Q000517:prevention & control