title: Diagnosis of liver cirrhosis: a comparison of modified ultrasound and laparoscopy in 100 consecutive patients.
abstract: OBJECTIVE
  Liver cirrhosis, the final stage of chronic liver disease, is characterized by an unfavorable prognosis and an increased risk of hepatocellular carcinoma and also requires an appropriate management. Laparoscopy, the gold standard in the diagnosis of cirrhosis, is hampered by its invasiveness. Therefore, a noninvasive method for diagnosing liver cirrhosis would be of great benefit.
  
  
  METHODS
  A consecutive series of 100 patients, sent to our gastroenterological unit for diagnostic laparoscopy, underwent a standardized ultrasonographic examination prior to laparoscopy.
  
  
  RESULTS
  Conventional ultrasonographic examination revealed a sensitivity of 55% and a specificity of 86% in the diagnosis of cirrhosis. Considering the assessment of the transmission of heart pulsation on the liver surface, the corresponding values improved by increasing to 85% and 93%.
  
  
  CONCLUSIONS
  Evaluating the transmission of heart pulsation on the liver surface improves the ability of ultrasound to diagnose liver cirrhosis; therefore, it should be an integral part of routine sonographic examination of the liver.
authors.affiliation: Department of Internal Medicine C, Klinikum Ludwigshafen, Academic Medical Hospital of the University of Mainz, Ludwigshafen am Rhein, Germany. weickeru@klilu.de
authors.forename: Uwe
authors.initials: U
authors.lastname: Weickert
authors.forename: Andrea
authors.initials: A
authors.lastname: Buttmann
authors.forename: Ralf
authors.initials: R
authors.lastname: Jakobs
authors.forename: Dieter
authors.initials: D
authors.lastname: Schilling
authors.forename: Axel
authors.initials: A
authors.lastname: Eickhoff
authors.forename: Jürgen Ferdinand
authors.initials: JF
authors.lastname: Riemann
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008103:Liver Cirrhosis / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014463:Ultrasonography