title: [Induction of anaesthesia with target-controlled inhalation of sevoflurane in adults with the ZEUS anaesthesia machine].
abstract: OBJECTIVE
  To evaluate if the new anaesthesia platform ZEUS (Dräger Medical) allows the induction of anaesthesia with target-controlled inhalation of sevoflurane.
  
  
  METHODS
  Prospective clinical study.
  
  
  METHODS
  Adult ASA I or II patients scheduled for elective surgery under general anaesthesia.
  
  
  METHODS
  After preoxygenation during 3 min at 100% oxygen, patients were asked to breathe normally; the target end-tidal concentration of sevoflurane was fixed at 4% without priming of the circuit. Sufentanil (target concentration 0.5 ng/ml) was administered 40 s after.
  
  
  RESULTS
  Ten patients (48+/-22 yrs) were included. Sevoflurane was detected in the circuit after 36+/-5 s; the target end-tidal concentration of sevoflurane was obtained at 130+/-19 s. Loss of consciousness was observed after 119+/-7 s. The induction was achieved in all patients without any incident.
  
  
  CONCLUSIONS
  This new anaesthesia system make available the induction of anaesthesia with sevoflurane without priming of the circuit.
authors.affiliation: Départements d'anesthésie-réanimation I et IV, CHU de Pellegrin, 33076 Bordeaux cedex, France.
authors.forename: K
authors.initials: K
authors.lastname: Nouette-Gaulain
authors.forename: P
authors.initials: P
authors.lastname: Lemoine
authors.forename: A-M
authors.initials: AM
authors.lastname: Cros
authors.forename: F
authors.initials: F
authors.lastname: Sztark
mesh_terms: D000328:Adult; D000368:Aged; D000769:Anesthesia, Inhalation / Q000009:adverse effects / Q000295:instrumentation*; D000776:Anesthesiology / Q000295:instrumentation*; D018685:Anesthetics, Inhalation / Q000008:administration & dosage* / Q000009:adverse effects; D016503:Drug Delivery Systems; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D008738:Methyl Ethers / Q000008:administration & dosage* / Q000009:adverse effects; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D011229:Preanesthetic Medication; D000077149:Sevoflurane
chemical_list: D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane