Role of relaxin in maternal renal vasodilation of pregnancy.
The remarkable hemodynamic changes of normal pregnancy are briefly reviewed. In addition, new findings and current concepts related to the underlying hormonal and molecular mechanisms are presented. Finally, work that is in progress as well as future directions is briefly discussed.
Conrad
Kirk P
KP
Department of Ob/Gyn and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee-Womens Research Institute, Pittsburgh, PA 15213, USA. rsikpc@mwri.magee.edu
Jeyabalan
Arun
A
Danielson
Leslie A
LA
Kerchner
Laurie J
LJ
Novak
Jacqueline
J
D000818:Animals; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007668:Kidney / Q000098:blood supply* / Q000378:metabolism* / Q000502:physiology; D011247:Pregnancy / Q000502:physiology*; D012065:Relaxin / Q000378:metabolism*; D014664:Vasodilation / Q000502:physiology*
D012065:Relaxin