Chromophobe renal cell carcinoma in a pediatric living-related kidney transplant recipient.
Renal cell carcinoma can occur in children who have received renal allografts from adults. Chromophobe renal cell carcinoma is a rare variant of renal carcinoma with distinct histochemical, ultrastructural, and genetic characteristics. We describe the incidental finding of a chromophobe renal cell carcinoma in a 13 1/2-year-old boy 5 years after receiving a living-related renal transplant. This tumor was found by serendipity during the evaluation of fever and inguinal lymphadenopathy, with the presumptive diagnosis of posttransplantation lymphoproliferative disorder. The patient was found to have cat-scratch disease. A renal cell carcinoma should be considered in the differential diagnosis of a pediatric recipient of an adult kidney with an incidental finding of a tumor in the graft.
Greco
Andres J
AJ
Department of Surgery, The Children's Hospital of Philadelphia, PA 19104, USA.
Baluarte
Jorge H
JH
Meyers
Kevin E C
KE
Sellers
Marty T
MT
Suchi
Mariko
M
Biegel
Jaclyn A
JA
Kaplan
Bernard S
BS
D000293:Adolescent; D002292:Carcinoma, Renal Cell / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D002372:Cat-Scratch Disease / Q000175:diagnosis*; D003937:Diagnosis, Differential; D018562:Disease Transmission, Infectious; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans; D016867:Immunocompromised Host; D007165:Immunosuppression Therapy / Q000009:adverse effects; D033162:Incidental Findings; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects*; D019520:Living Donors; D008207:Lymphatic Metastasis / Q000175:diagnosis; D008232:Lymphoproliferative Disorders / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009035:Mothers; D009392:Nephrectomy; D009395:Nephritis, Interstitial / Q000235:genetics / Q000601:surgery; D011183:Postoperative Complications / Q000175:diagnosis*; D014184:Transplantation, Homologous / Q000009:adverse effects*