title: Successful medical treatment of multiple brain abscesses due to Nocardia farcinica in a paediatric renal transplant recipient.
abstract: Brain abscesses caused by Nocardia are rare, but it is very important to detect and treat them early because the associated mortality is 3 times higher than that associated with other bacterial brain abscesses. This infection is prevalent among adults on long-term immunosuppressive therapy; we report the case of a male kidney transplant recipient aged 12.7 years who developed early multiple Nocardia-induced brain abscesses that were successfully treated with linezolid, a novel antibiotic therapy.
authors.affiliation: ICP Pediatric Nephrology, Dialysis and Transplantation Unit, Milan, Italy.
authors.forename: Sara Maria
authors.initials: SM
authors.lastname: Viganò
authors.forename: Alberto
authors.initials: A
authors.lastname: Edefonti
authors.forename: Mariano
authors.initials: M
authors.lastname: Ferraresso
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Ranzi
authors.forename: Paolo
authors.initials: P
authors.lastname: Grossi
authors.forename: Andrea
authors.initials: A
authors.lastname: Righini
authors.forename: Roberto
authors.initials: R
authors.lastname: Rusconi
authors.forename: Luigi
authors.initials: L
authors.lastname: Santambrogio
authors.forename: Luciana
authors.initials: L
authors.lastname: Ghio
mesh_terms: D000081:Acetamides / Q000627:therapeutic use*; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001922:Brain Abscess / Q000188:drug therapy*; D002648:Child; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D000069349:Linezolid; D008297:Male; D009617:Nocardia Infections / Q000188:drug therapy*; D023303:Oxazolidinones / Q000627:therapeutic use*
chemical_list: D000081:Acetamides; D000890:Anti-Infective Agents; D023303:Oxazolidinones; D000069349:Linezolid