[Neurotoxic encephalopathy caused by neuroleptics and lithium].
Treatment of psychiatric patients often necessitates overlapping neuroleptic medication. We report a 60-year-old woman suffering from a schizoaffective disorder who received temporarily three neuroleptics, together with lithium. She developed neurotoxic encephalopathy with symptoms of a malignant neuroleptic syndrome. It is unclear if irreversible brain damage will remain. We recommend frequent electroencephalographic controls for early detection of neurotoxicity.
Lambreva
E
E
Abteilung Psychosoziale Medizin, Universitätsspital Zürich, Schweiz. evelina.lambreva@usz.ch
Vecellio
M
M
Wieser
H G
HG
Buddeberg
C
C
D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D004338:Drug Combinations; D004569:Electroencephalography / Q000379:methods; D005260:Female; D006801:Humans; D008094:Lithium / Q000009:adverse effects* / Q000627:therapeutic use*; D008875:Middle Aged; D020258:Neurotoxicity Syndromes / Q000175:diagnosis* / Q000209:etiology* / Q000517:prevention & control; D011379:Prognosis; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy*
D014150:Antipsychotic Agents; D004338:Drug Combinations; D008094:Lithium