title: A 9-year-old boy with a history of large perinatal stroke, infantile spasms, and high academic achievement.
abstract: The prognosis for intellectual development in children with symptomatic infantile spasms is usually poor. We report a 9-year-old boy with a history of a large, presumed perinatal, left middle cerebral artery infarct discovered when he developed infantile spasms at 6 months of age. The infantile spasms responded to treatment with adrenocorticotropic hormone. He attained cognitive milestones at normal times, requiring only speech therapy for dysarthric speech. At 9 years of age, he has seizures and a severe right hemiparesis but is an articulate honor roll student in advanced English classes. The development of infantile spasms after large-branch middle cerebral artery stroke does not always predict future mental retardation.
authors.affiliation: Department of Neurology, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN 46202, USA. mgolomb@iupui.edu
authors.forename: Meredith R
authors.initials: MR
authors.lastname: Golomb
authors.forename: Karen S
authors.initials: KS
authors.lastname: Carvalho
authors.forename: Bhuwan P
authors.initials: BP
authors.lastname: Garg
mesh_terms: D001076:Aptitude; D004522:Educational Status; D005315:Fetal Diseases / Q000473:pathology / Q000523:psychology*; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D020244:Infarction, Middle Cerebral Artery / Q000150:complications / Q000473:pathology / Q000523:psychology*; D008297:Male; D013036:Spasms, Infantile / Q000209:etiology / Q000473:pathology / Q000523:psychology*