title: Expression and regulation of CCR1 in peritoneal macrophages from women with and without endometriosis.
abstract: CCR1 is a CC chemokine receptor with high affinity for RANTES (regulated upon activation, normal T cells expressed and secreted). CCR1 protein and mRNA concentrations in native peritoneal cells were twofold greater, in cultured peritoneal cells threefold greater, in patients with endometriosis compared to patients without endometriosis, as determined by Western blotting fluorescence activated cell sorting analysis, reverse transcription-polymerase chain reaction, and in situ hybridization.
authors.affiliation: Center for Reproductive Sciences, Department of Obstetrics and Gynecology, University of California, San Francisco, California, USA.
authors.forename: Fritz
authors.initials: F
authors.lastname: Wieser
authors.forename: Songül
authors.initials: S
authors.lastname: Dogan
authors.forename: Karin
authors.initials: K
authors.lastname: Klingel
authors.forename: Klaus
authors.initials: K
authors.lastname: Diedrich
authors.forename: Robert N
authors.initials: RN
authors.lastname: Taylor
authors.forename: Daniela
authors.initials: D
authors.lastname: Hornung
mesh_terms: D000704:Analysis of Variance; D002478:Cells, Cultured; D004715:Endometriosis / Q000235:genetics / Q000378:metabolism*; D005260:Female; D005434:Flow Cytometry; D005786:Gene Expression Regulation / Q000502:physiology; D006801:Humans; D017403:In Situ Hybridization; D017737:Macrophages, Peritoneal / Q000378:metabolism*; D054389:Receptors, CCR1; D019707:Receptors, Chemokine / Q000096:biosynthesis* / Q000235:genetics / Q000502:physiology; D020133:Reverse Transcriptase Polymerase Chain Reaction; D018709:Statistics, Nonparametric
chemical_list: C515300:CCR1 protein, human; D054389:Receptors, CCR1; D019707:Receptors, Chemokine