title: Intraocular lens power prediction for triple procedures in Fuchs' dystrophy using multiple regression analysis.
abstract: OBJECTIVE
  To develop a correcting term for intraocular power (IOLP) prediction for penetrating keratoplasty combined with simultaneous extracapsular cataract extraction and posterior chamber lens implantation (triple procedure).
  
  
  METHODS
  As part of a prospective clinical study, triple procedures were performed in 42 eyes with Fuchs' dystrophy. Only eyes with readable preoperative K-values were included in this study. Differences (DEV) between achieved and target refraction (TR) depending on the values of the theoretical-optical formula according to HAIGIS were investigated using multiple regression analysis in a linear anova model: DEV = a + b CP + c AL + d IOLP + e TR. CP represents central corneal power, AL represents axial length.
  
  
  RESULTS
  Spherical equivalent after suture removal was - 1.39 +/- 2.86 D (TR: - 1.64 +/- 1.72 D). A multiple regression formula was developed for correction of conventionally calculated IOL power. CP (b = - 1.391, p = 0.028), AL (c = - 4.733, p = 0.007), IOLP (d = - 1.301, p = 0.009) and TR (e = - 1.804, p = 0.005) correlated significantly with DEV (a = 198.684).
  
  
  CONCLUSIONS
  Proposed correcting multiple regression formula for IOL power prediction may help to improve the postoperative refractive outcome in patients undergoing triple procedures.
authors.affiliation: Department of Ophthalmology, University of Erlangen-Nürnberg, Erlangen, Germany. anja.viestenz@augen.imed.uni-erlangen.de
authors.forename: Anja
authors.initials: A
authors.lastname: Viestenz
authors.forename: Berthold
authors.initials: B
authors.lastname: Seitz
authors.forename: Achim
authors.initials: A
authors.lastname: Langenbucher
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000150:complications / Q000628:therapy; D002387:Cataract Extraction / Q000379:methods*; D005260:Female; D005642:Fuchs' Endothelial Dystrophy / Q000150:complications / Q000601:surgery*; D006801:Humans; D015948:Keratoplasty, Penetrating / Q000379:methods*; D019654:Lens Implantation, Intraocular / Q000379:methods*; D007910:Lenses, Intraocular; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D055095:Optics and Photonics; D011446:Prospective Studies; D012029:Refraction, Ocular; D012044:Regression Analysis; D014792:Visual Acuity