title: Middle cerebral artery infarction: relationship of cavernous carotid artery calcification.
abstract: OBJECTIVE
  This study was designed to determine whether calcification of the cavernous carotid artery (CCA) is associated with cerebrovascular infarcts in the same way that coronary artery calcification scores indicate myocardial infarctions. We sought to correlate the grade of CCA calcification with infarctions in the middle cerebral artery (MCA) distribution.
  
  
  METHODS
  Nonenhanced brain CT scans of 40 patients with MCA-distribution strokes, 34 with non-MCA-distribution strokes, and 94 age-matched control subjects were reviewed. Circumferential calcification and thickness of calcification were graded for the CCAs on head CT scans. Scores were determined for the left and right CCAs. Mann-Whitney tests and Spearman correlation coefficients were used to detect differences between patients and control subjects and between patients with MCA and those with non-MCA strokes.
  
  
  RESULTS
  CCA calcification scores did not significantly differ in the groups compared. The manner in which calcification was scored (by using circumference, thickness, or both) did not affect the results. No difference was noted between scores ipsilateral and those contralateral to the stroke.
  
  
  CONCLUSIONS
  Circumferential degree or thickness of cavernous artery calcification was not correlated with MCA or non-MCA infarctions. CCA calcification scores did not differ between patients with stroke and those without stroke.
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Sciences, the Johns Hopkins Hospital, Baltimore, MD 21287, USA.
authors.forename: Lukasz S
authors.initials: LS
authors.lastname: Babiarz
authors.forename: David M
authors.initials: DM
authors.lastname: Yousem
authors.forename: Warren
authors.initials: W
authors.lastname: Bilker
authors.forename: Bruce A
authors.initials: BA
authors.lastname: Wasserman
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002114:Calcinosis / Q000150:complications* / Q000000981:diagnostic imaging; D002340:Carotid Artery Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000150:complications* / Q000000981:diagnostic imaging; D008875:Middle Aged; D011859:Radiography