Blepharoplasty and otoplasty: comparative sedation with remifentanil,propofol, and midazolam.
Three different methods of sedation or sedoanalgesia using remifentanil, Propofol, or midazolam to increase intra- and postoperative comfort and to reduce neuroendocrine stress in patients who had undergone typical ambulatory cosmetic surgery under local anesthesia were studied. A sample of 90 patients who underwent upper and lower eyelid blepharoplasty to correct baggy eyelids or otoplasty to correct protruding ears was selected according to standard criteria for the study. Remifentanil provided the best tolerability profile and the most effective perioperative pain control among the substances studied, demonstrating it to be a valid drug for modern sedoanalgesia aimed at increasing the well-being of patients undergoing ambulatory cosmetic surgery.
Ferraro
G A
GA
gaferraro@libero.it
Corcione
A
A
Nicoletti
G
G
Rossano
F
F
Perrotta
A
A
D'Andrea
F
F
D000293:Adolescent; D000328:Adult; D000368:Aged; D019882:Blepharoplasty; D016292:Procedural Sedation / Q000379:methods*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006993:Hypnotics and Sedatives / Q000494:pharmacology; D008297:Male; D008875:Middle Aged; D013506:Otologic Surgical Procedures; D010880:Piperidines / Q000494:pharmacology; D015742:Propofol / Q000494:pharmacology; D019651:Plastic Surgery Procedures; D000077208:Remifentanil
D006993:Hypnotics and Sedatives; D010880:Piperidines; D000077208:Remifentanil; D015742:Propofol