title: The use of a continuous flow-reactor employing a mixed hydrogen-liquid flow stream for the efficient reduction of imines to amines.
abstract: Imines have been reduced to amines in high yield, and with excellent chemoselectivity, by catalytic hydrogenation in a continuous flow-reactor, utilising an electrochemically-generated hydrogen source to produce a mixed hydrogen-liquid flow stream.
authors.affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UKCB2 1EW.
authors.forename: Steen
authors.initials: S
authors.lastname: Saaby
authors.forename: Kristian Rahbek
authors.initials: KR
authors.lastname: Knudsen
authors.forename: Mark
authors.initials: M
authors.lastname: Ladlow
authors.forename: Steven V
authors.initials: SV
authors.lastname: Ley
mesh_terms: D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques / Q000295:instrumentation / Q000379:methods; D006859:Hydrogen / Q000737:chemistry*; D006865:Hydrogenation; D007097:Imines / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: D000588:Amines; D007097:Imines; D006859:Hydrogen