[Study on serum leptin level of urban resident and the relationship between body mass index, blood lipid, insulin and leptin level].
OBJECTIVE
To measure serum leptin concentration of urban residents and investigate the relationship between serum leptin concentration and body mass index(BMI), blood lipid, insulin.


METHODS
One hundred fifty-eight men and women ages 18-72 years were initially drawn from a community in Ji'nan City. The parameters measured included height, weight, waist and hip circumference, insulin, blood lipid and leptin concentrations. Statistical analyses were performed with SPSS11.5.


RESULTS
The mean serum concentration of leptin was (17.47 +/- 13.52)ng/ml, in male subjects was (8.38 +/- 6.31)ng/ml, in female subjects it was (24.98 +/- 13.29)ng/ml. Serum level of leptin was significantly positively correlated with BMI, waist and hip circumference, not correlated with WHR. Serum leptin level in females was positively correlated with WHR. There was no association between serum level of leptin and insulin. Serum leptin level in males was positively correlated to apo B, in females was positively correlated to TC, LDL-c.


CONCLUSIONS
BMI is an important factor to determine serum leptin level. The relationships between plasma glucose, insulin, blood lipids and serum leptin are affected by gender. In males serum leptin level was positively correlated to apo B, in females was positively correlated to TC, LDL-c. We need further research to explain this difference.
Xu
Gui-fa
GF
School of Public Health, Shandong University, Ji'nan 250012, China.
Zhu
Feng
F
Liu
Chun-xiao
CX
Li
Hui
H
Shi
Mai
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood*; D020738:Leptin / Q000097:blood*; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D014504:Urban Health
D007328:Insulin; D020738:Leptin; D008055:Lipids