Paradoxical deterioration during anti-tubercular treatment in a dialysis patient on maintenance steroid therapy.
We report a 38-year-old Chinese woman with lupus nephritis on peritoneal dialysis and long-term maintenance steroid therapy. This patient developed paradoxical deterioration during anti-tubercular therapy for tuberculous lymphadenitis. The deterioration resolved spontaneously without change to pharmacotherapy. Paradoxical deterioration that may spontaneously resolve is a potential complication of anti-tubercular treatment in patients on long-term renal replacement therapy.
Hung
I F N
IF
Division of Nephrology, Department of Medicine, Tung Wah Hospital, Hong Kong.
Cheng
V C C
VC
Lo
W K
WK
Lui
S L
SL
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008181:Lupus Nephritis / Q000628:therapy*; D010531:Peritoneal Dialysis, Continuous Ambulatory; D014388:Tuberculosis, Lymph Node / Q000188:drug therapy*
D000305:Adrenal Cortex Hormones; D000995:Antitubercular Agents