Clinical Relevance of the vacA, iceA, cagA, and flaA genes of Helicobacter pylori strains isolated in Eastern Taiwan.
The genotypes of Helicobacter pylori flaA, cagA, vacA, and iceA were determined for DNA isolated from patients with chronic gastritis or peptic ulcer in eastern Taiwan. The vacA gene encoding the s1a subtype was found to predominate in peptic ulcer patients, and the iceA1 genotype was associated with chronic gastritis. cagA and flaA genes were not found to be associated with these types of disease.
Wu
Chao-Chuan
CC
Department of Surgery, Tzu Chi University, Hualien 970, Taiwan.
Chou
Pai-Yu
PY
Hu
Chi-Tan
CT
Liu
Zuo-Chai
ZC
Lin
Chih-Yung
CY
Tseng
Yi-Hsiung
YH
Lin
Nien-Tsung
NT
D000328:Adult; D000368:Aged; D000942:Antigens, Bacterial / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics*; D002908:Chronic Disease; D005260:Female; D005408:Flagellin / Q000235:genetics*; D005756:Gastritis / Q000382:microbiology; D005838:Genotype; D016481:Helicobacter Infections / Q000382:microbiology / Q000503:physiopathology*; D016480:Helicobacter pylori / Q000145:classification / Q000235:genetics / Q000472:pathogenicity*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000382:microbiology; D013624:Taiwan
D000942:Antigens, Bacterial; D001426:Bacterial Proteins; C074689:VacA protein, Helicobacter pylori; C080866:cagA protein, Helicobacter pylori; C405087:iceA1 protein, Helicobacter pylori; D005408:Flagellin; C067138:flaA protein, bacteria