title: [Internal carotid artery vasculitis originated by cervicofacial actinomycosis as a predisponing factor to stroke].
abstract: Actinomycosis is a chronic, suppurative, fibrotic infection produced by a gram-positive anaerobic bacteria of the normal mouth flora, the infection having tendency to fistulate and to extend without respecting tissue layers. Initial diagnosis is usually delayed due to its painless evolution. Three clinical forms are known: cervicofacial, abdominal and thoracic. Occasionally, there is vascular involvement which is mainly associated with venous thrombotic phenomena with low clinical expresion and hematogenous dissemination that can result in a formation of abscess or meningitis in the central nervous system. We report the case of a 28 year old female patient with type I diabetes and microangiopathyc complication with a internal carotid artery stenosis adjacent to mandibular angle actinomicosis. A few months later and after a miscarriage she suffered from ischemic stroke. The anticardiolipin antibody were positive at the time of stroke with post-operative period and over the next two years. To our knowledge (Medline, 1984-2004), it is the first report of internal carotid vasculitis originated by cervicofacial actinomicosis. We discuss the neuroradiological aspects of our case.
authors.affiliation: Sección de Neurología, Hospital Universitario Infanta Cristina, Badajoz, Spain.
authors.forename: J J
authors.initials: JJ
authors.lastname: Aguirre-Sánchez
authors.forename: J C
authors.initials: JC
authors.lastname: Portilla-Cuenca
authors.forename: M R
authors.initials: MR
authors.lastname: Velicia Mata
authors.forename: R
authors.initials: R
authors.lastname: Querol-Pascual
authors.forename: R
authors.initials: R
authors.lastname: Palacios Bote
authors.forename: A
authors.initials: A
authors.lastname: Campos de Orellana
mesh_terms: D000197:Actinomycosis, Cervicofacial / Q000150:complications*; D000328:Adult; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging / Q000473:pathology*; D002533:Cerebral Angiography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D020521:Stroke / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D020293:Vasculitis, Central Nervous System / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*