title: Growth hormone secretion and insulin-like growth factor-1 are related to hyperandrogenism in nonobese patients with polycystic ovary syndrome.
abstract: Women of normal weight with polycystic ovary syndrome (PCOS) and hyperinsulinemia presented high growth hormone (GH) levels in response to the l-dopa test, suggesting that the action of GH and insulin-like growth factor-1 (IGF-1) might be responsible for the elevation in LH and the consequent hyperandrogenic anovulation observed in normal weight women with PCOS. Insulin resistance and obesity are related to a reduction in GH secretion in obese women with PCOS.
authors.affiliation: Department of Gynecology and Obstetrics, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.
authors.forename: Ana Cristina
authors.initials: AC
authors.lastname: Premoli
authors.forename: Laura Ferreira
authors.initials: LF
authors.lastname: Santana
authors.forename: Rui Alberto
authors.initials: RA
authors.lastname: Ferriani
authors.forename: Marcos Dias de
authors.initials: MD
authors.lastname: Moura
authors.forename: Marcos Felipe Silva
authors.initials: MF
authors.lastname: De Sá
authors.forename: Rosana Maria dos
authors.initials: RM
authors.lastname: Reis
mesh_terms: D000328:Adult; D005260:Female; D019382:Human Growth Hormone / Q000097:blood* / Q000378:metabolism*; D006801:Humans; D017588:Hyperandrogenism / Q000097:blood*; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D009765:Obesity / Q000097:blood*; D011085:Polycystic Ovary Syndrome / Q000097:blood*; D011446:Prospective Studies
chemical_list: D019382:Human Growth Hormone; D007334:Insulin-Like Growth Factor I