title: Management for postoperative complications of breast augmentation by injected polyacrylamide hydrogel.
abstract: Polyacrylamide hydrogel, a new biomaterial, has been used for injected breast augmentation in China since 1997. A series of 30 patients with various complications after injected polyacrylamide hydrogel visited the author's department. Most of these patients had undergone injection of both breasts. The average age of the patients was 27.6 years, and the time of consultation for the complications was from 3 to 36 months postopertively. Nearly all the patients had breast lumps and other common complications including breast pain, disfigurement, and infection. Ultrasound examination showed diffuse, irregular, anechoic zones of mammary tissue. Pathologic results indicated inflammatory cell infiltration and fibrous capsular formation. An open suction technique and partial mastectomies via periareolar incisions were performed for the all patients. Most of their symptoms were relieved after removal of the polyacrylamide hydrogel. Only one patient had undergone immediate breast reconstruction with implants, whereas five patients had received breast implants secondarily via an axillary incision. The authors conclude that polyacrylamide hydrogel should be prohibited for injected breast augmentation before more scientific data are available about the long effect of the gel in breast tissue.
authors.affiliation: Department of Plastic and Cosmetic Surgery, Peking Union Medical College Hospital, Beijing, 100730, China.
authors.forename: Qun
authors.initials: Q
authors.lastname: Qiao
authors.forename: Xiancheng
authors.initials: X
authors.lastname: Wang
authors.forename: Jiaming
authors.initials: J
authors.lastname: Sun
authors.forename: Ru
authors.initials: R
authors.lastname: Zhao
authors.forename: Zhifei
authors.initials: Z
authors.lastname: Liu
authors.forename: Yang
authors.initials: Y
authors.lastname: Wang
authors.forename: Baodong
authors.initials: B
authors.lastname: Sun
authors.forename: Yinjun
authors.initials: Y
authors.lastname: Yan
authors.forename: Keming
authors.initials: K
authors.lastname: Qi
mesh_terms: D000180:Acrylic Resins / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D019928:Breast Implantation / Q000009:adverse effects*; D018427:Breast Implants; D005260:Female; D006801:Humans; D007267:Injections; D016217:Ultrasonography, Mammary
chemical_list: D000180:Acrylic Resins; C016680:polyacrylamide gels