Long-term use of oral contraceptives increases the risk of miscarriage.
In this prospective, case-control study, a step-wise logistic regression model was used to examine the relationship between the consumption of oral contraceptives before pregnancy and the potential increase in the risk of miscarriage. Consumption of oral contraceptives for more than 2 years before pregnancy is associated with a higher risk of miscarriage.
García-Enguídanos
Alberto
A
Unidad de Reproducción Humana, Clínica Tambre, Madrid, Spain. agarciaen@sego.es
Martínez
David
D
Calle
Maria Elisa
ME
Luna
Sonsoles
S
Valero de Bernabé
Javier
J
Domínguez-Rojas
Vincente
V
D000022:Abortion, Spontaneous / Q000139:chemically induced* / Q000453:epidemiology; D000328:Adult; D016022:Case-Control Studies; D016001:Confidence Intervals; D003276:Contraceptives, Oral / Q000009:adverse effects*; D005260:Female; D006801:Humans; D016015:Logistic Models; D016017:Odds Ratio; D011247:Pregnancy; D011446:Prospective Studies; D012307:Risk Factors; D013995:Time
D003276:Contraceptives, Oral