title: Kikuchi-Fujimoto disease is a rare cause of lymphadenopathy and fever of unknown origin in children: report of two cases and review of the literature.
abstract: Kikuchi-Fujimoto disease, a benign and unusual self-limiting histiocytic necrotizing lymphadenitis of unknown origin, should be included in the differential diagnosis of lymphadenopathy and fever of unknown origin. This disease mostly affects young Asian women and has rarely been reported in children, thus remaining a poorly recognized entity that is frequently confused with malignant lymphoma. The authors describe two children with Kikuchi-Fujimoto disease, with particular attention to diagnostic approach and clinical and histologic features of the disease.
authors.affiliation: Department of Pediatrics, Children's Hospital Regina Margherita, Piazza Polonia 94, 10126 Turin, Italy. scagni@hotmail.com
authors.forename: Paola
authors.initials: P
authors.lastname: Scagni
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Peisino
authors.forename: Maurizio
authors.initials: M
authors.lastname: Bianchi
authors.forename: Maura
authors.initials: M
authors.lastname: Morello
authors.forename: Nicola
authors.initials: N
authors.lastname: Sardi
authors.forename: Alessandra
authors.initials: A
authors.lastname: Linari
authors.forename: Luana
authors.initials: L
authors.lastname: Mastrodicasa
authors.forename: Enrico
authors.initials: E
authors.lastname: Madon
authors.forename: Paola
authors.initials: P
authors.lastname: Pecco
mesh_terms: D000293:Adolescent; D001706:Biopsy; D002648:Child; D005335:Fever of Unknown Origin / Q000209:etiology*; D020042:Histiocytic Necrotizing Lymphadenitis / Q000150:complications* / Q000473:pathology; D006801:Humans; D008206:Lymphatic Diseases / Q000209:etiology* / Q000473:pathology; D008297:Male