title: Cronkhite-Canada syndrome with hypothyroidism.
abstract: Cronkhite-Canada syndrome is a rare, noninherited gastrointestinal polyposis syndrome associated with characteristic ectodermal abnormalities. This report describes a 60-year-old female who was diagnosed with Cronkhite-Canada syndrome with hypothyroidism after presenting with chronic diarrhea, alopecia, intermittent abdominal pain, generalized gastrointestinal polyposis, hyperpigmentation, and nail dystrophy. Endoscopic examination of the stomach and duodenum showed multiple sessile polyps and mucosal erosion associated with evidence of chronic inflammation. Colonoscopy also revealed mucosal edema and diffuse polyposis.
authors.affiliation: Digestive Department, The First Affiliated Hospital of Anhui Medical University, Heifei, China. meiqiao@hotmail.com
authors.forename: Mei
authors.initials: M
authors.lastname: Qiao
authors.forename: Zhang
authors.initials: Z
authors.lastname: Lei
authors.forename: Hu
authors.initials: H
authors.lastname: Nai-Zhong
authors.forename: Xu
authors.initials: X
authors.lastname: Jian-Ming
mesh_terms: D003113:Colonoscopy; D005260:Female; D006801:Humans; D007037:Hypothyroidism; D044483:Intestinal Polyposis / Q000473:pathology; D008875:Middle Aged