title: Photocontrolling peptide alpha helices.
abstract: Reversible optical control of protein structure and function offers the possibility of probing and manipulating individual proteins within the complex environment of a living cell. As a first step toward creating artificial photocontrolled proteins, we have designed and synthesized reversible, photocontrolled peptide alpha helices. Here, I attempt to summarize the lessons learned from that endeavor.
authors.affiliation: Department of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada. awoolley@chem.utoronto.ca
authors.forename: G Andrew
authors.initials: GA
authors.lastname: Woolley
mesh_terms: D000595:Amino Acid Sequence; D007536:Isomerism; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry*; D010777:Photochemistry; D017433:Protein Structure, Secondary
chemical_list: D010455:Peptides