title: Improving adherence to highly active anti-retroviral therapy in Africa: the DREAM programme in Mozambique.
abstract: Ensuring high levels of adherence to highly active anti-retroviral therapy (HAART) is a priority in treating people living with AIDS. This study reports the rates of adherence of patients served by DREAM (Drug Resource Enhancement against AIDS and Malnutrition) in the city of Matola, Mozambique. DREAM, an innovative programme tailored for Africa, was implemented by the Community of Sant'Egidio in August 2001. DREAM provides patients with anti-retroviral drugs and laboratory tests at no charge, and is based on a particular strategy of health education and organization of services designed for a population that is predominantly poor and has a low level of formal education. This study analyzes the adherence of 154 patients over a period of 6 months. In evaluating adherence, two indicators were used: (1) the percentage of appointments kept for check-ups, tests and the collection of medicine, and (2) the overall change in the patients' blood chemistry over the 6-month period. Of the 154 patients, 127 (82.5%) kept more than 90% of their appointments. Adherence to the programme was further confirmed by a relevant increase of hemoglobin levels and CD4 counts, and a significant decrease in the viral loads among the 154 patients.
authors.affiliation: LUMSA University, 00193 Rome, Italy.
authors.forename: M C
authors.initials: MC
authors.lastname: Marazzi
authors.forename: M
authors.initials: M
authors.lastname: Bartolo
authors.forename: L
authors.initials: L
authors.lastname: Emberti Gialloreti
authors.forename: P
authors.initials: P
authors.lastname: Germano
authors.forename: G
authors.initials: G
authors.lastname: Guidotti
authors.forename: G
authors.initials: G
authors.lastname: Liotta
authors.forename: M
authors.initials: M
authors.lastname: Magnano San Lio
authors.forename: S
authors.initials: S
authors.lastname: Mancinelli
authors.forename: M A
authors.initials: MA
authors.lastname: Modolo
authors.forename: P
authors.initials: P
authors.lastname: Narciso
authors.forename: C F
authors.initials: CF
authors.lastname: Perno
authors.forename: P
authors.initials: P
authors.lastname: Scarcella
authors.forename: G
authors.initials: G
authors.lastname: Tintisona
authors.forename: L
authors.initials: L
authors.lastname: Palombi
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009073:Mozambique; D010349:Patient Compliance; D010353:Patient Education as Topic; D012189:Retrospective Studies