title: CT-estimated volume of Wilms tumor can predict weight.
abstract: Wilms tumor weight was used to recruit patients in a recent National Wilms Tumor Study (NWTS) group trial. The authors hypothesized that a simple calculation of tumor volume based on a preoperative CT scan could predict tumor weight. The authors reviewed charts and CT images of patients with Wilms tumors who were treated at their institution between 1985 and 2002. Tumor volume was calculated as: V = 1/6pi x d (long axis) x d (short axis) x d (craniocaudal). Weight and calculated tumor volume were correlated using linear regression. Complete data of tumor weight and volume could be determined in 25 of the 49 patients. These were highly correlated (Spearman R = 0.97). Wilms tumor weight can be predicted based on a simple estimate of tumor volume on a preoperative CT scan. CT-estimated volume may replace weight as a prognostic factor and in guiding management.
authors.affiliation: IWK Health Centre, PO BGox 3070, 5850 University Avenue, Halifax, Nova Scotia, Canada B3K 6R8.
authors.forename: Saud
authors.initials: S
authors.lastname: Al-Shanafey
authors.forename: Natalie L
authors.initials: NL
authors.lastname: Yanchar
authors.forename: Matthias H
authors.initials: MH
authors.lastname: Schmidt
authors.forename: Suyin Lum
authors.initials: SL
authors.lastname: Min
authors.forename: Margaret
authors.initials: M
authors.lastname: Yhap
mesh_terms: D000293:Adolescent; D002648:Child; D006801:Humans; D015994:Incidence; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000453:epidemiology; D009929:Organ Size; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*; D009396:Wilms Tumor / Q000000981:diagnostic imaging* / Q000453:epidemiology