Brooke-Spiegler syndrome: treatment with laser ablation.
Brooke-Spiegler syndrome is a rare genetic condition associated with adnexal and epidermal tumours. Facial trichoepitheliomas and cylindromas are particularly distressing to sufferers. Conventional treatment can be followed by recurrence. We report a case with disfiguring trichoepithelioma treated with erbium:Yag and CO2 laser, achieving a good cosmetic result without recurrence after 2 years. Brooke-Spiegler syndrome and its treatment are reviewed.
Rallan
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Department of Dermatology, St Helier Hospital, Carshalton, UK. DeepakRallan@aol.com
Harland
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D000328:Adult; D005153:Facial Neoplasms / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D053685:Laser Therapy; D018295:Neoplasms, Basal Cell / Q000532:radiotherapy; D009386:Neoplastic Syndromes, Hereditary / Q000532:radiotherapy*; D012878:Skin Neoplasms / Q000532:radiotherapy; D013577:Syndrome