Is there a role for chemoradiation in the management of cystadenocarcinoma of the pancreas?
Despite a paucity of data, cystadenocarcinoma of the pancreas has been considered to be resistant to chemoradiation, with a limited effect similar to that of the more common pancreatic adenocarcinoma. We describe a case of a partially excised cystadenocarcinoma with a positive surgical margin that was treated by neoadjuvant chemoradiation. No epithelial elements were found on histologic examination after reresection. Three previous cases of dramatic response of pancreatic cystadenocarcinoma to chemoradiation have been described in the literature. The current dogma alleging poor response of pancreatic cystadenocarcinoma to chemoradiation may be in error.
Bradley
Edward L
EL
Department of Clinical Sciences (Surgery), Florida State University College of Medicine, Tallahassee, FL, USA. ed.bradley@med.fsu.edu
Satchidanand
Sateesh K
SK
D000328:Adult; D002272:Carcinoembryonic Antigen / Q000032:analysis; D003131:Combined Modality Therapy; D003536:Cystadenocarcinoma / Q000097:blood / Q000473:pathology / Q000628:therapy*; D005260:Female; D006801:Humans; D010190:Pancreatic Neoplasms / Q000097:blood / Q000473:pathology / Q000628:therapy*; D014057:Tomography, X-Ray Computed
D002272:Carcinoembryonic Antigen