Addressing the global cardiovascular risk of hypertension, dyslipidemia, and insulin resistance in the southeastern United States.
An expanded occurrence of the metabolic syndrome in the U.S. population, especially in the Southeastern United States, has raised awareness of a need to revise our approach to the management of global cardiovascular risk factors while underscoring a need for more aggressive interventions and prevention measures. In defining the components of the metabolic syndrome and the interrelationship among obesity, hypertension, dyslipidemia, and insulin resistance, a basic framework for the medical management of this syndrome has been defined. In Part I of the consensus report prepared by the Workgroup on Medical Guidelines of the Consortium for Southeastern Hypertension Control (COSEHC), we analyze the components of the metabolic syndrome, discuss its pathophysiology, and recommend an approach to the quantitative analysis of the risk factors contributing to excess cardiovascular death in the region.
Houston
Mark C
MC
Consortium for Southeastern Hypertension Control (COSEHC) and Vanderbilt University School of Medicine and St. Thomas Hospital, Nashville, Tennessee, USA.
Basile
Jan
J
Bestermann
William H
WH
Egan
Brent
B
Lackland
Daniel
D
Hawkins
Ralph G
RG
Moore
Michael A
MA
Reed
James
J
Rogers
Philip
P
Wise
Daniel
D
Ferrario
Carlos M
CM
D000328:Adult; D000367:Age Factors; D000368:Aged; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000209:etiology*; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications*; D006973:Hypertension / Q000150:complications* / Q000453:epidemiology; D024821:Metabolic Syndrome / Q000150:complications*; D008875:Middle Aged; D012307:Risk Factors; D012737:Sex Factors; D015144:Southeastern United States / Q000453:epidemiology