title: Chemical composition and antimicrobial activity of the essential oil of Artemisia lavandulaefolia.
abstract: The chemical components of the essential oil obtained from Artemisia lavandulaefolia DC. were analyzed by GC-MS. Ninety-nine compounds accounting for 94.9 % of the essential oil were identified. The major compounds in the essential oil were beta-caryophyllene (16.1 %), cis-chrysanthenol (7.0 %), 1,8-cineole (5.6 %), borneol (5.3 %), trans-beta-farnesene (5.1 %), camphor (4.9 %), yomogi alcohol (4.5 %), alpha-terpineol (3.9 %), and alpha-humulene oxide (3.3 %). The essential oil and some of its major compounds were tested for antimicrobial activity against 15 different genera of oral bacteria. The essential oil of A. lavandulaefolia exhibited considerable inhibitory effects against all obligate anaerobic bacteria (MIC values, 0.025 to 0.05 mg/mL; MBC values, 0.025 to 0.1 mg/mL) tested, while its major compounds demonstrated different degrees of growth inhibition.
authors.affiliation: Institute of Oral Bioscience and Department of Oral Microbiology, School of Dentistry, Chonbuk National University, Jeonju, South Korea.
authors.forename: Jeong-Dan
authors.initials: JD
authors.lastname: Cha
authors.forename: Mi-Ran
authors.initials: MR
authors.lastname: Jeong
authors.forename: Hwa-Jung
authors.initials: HJ
authors.lastname: Choi
authors.forename: Seung-Il
authors.initials: SI
authors.lastname: Jeong
authors.forename: Sang-Eun
authors.initials: SE
authors.lastname: Moon
authors.forename: Soon-Il
authors.initials: SI
authors.lastname: Yun
authors.forename: Young-Hoi
authors.initials: YH
authors.lastname: Kim
authors.forename: Bong-Seop
authors.initials: BS
authors.lastname: Kil
authors.forename: Yo-Han
authors.initials: YH
authors.lastname: Song
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D019306:Artemisia; D008401:Gas Chromatography-Mass Spectrometry; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006801:Humans; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D010938:Plant Oils / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D010938:Plant Oils