[Immunophenotype of lymphoblastic leukaemia in children in relation to clinical symptoms and laboratory tests, preceding its diagnosis].
The aim of study was to compare the clinical picture and results of laboratory tests according to the acute lymphoblastic leukaemia (ALL) immunophenotype. The observation was carried out on a group of 67 patients treated in the IIIrd Department of Paediatrics and Department of Children Oncology in the Medical Academy of Białystok from January 1994 to April 2001. This group consists of 4 children with pro-B acute lymphoblastic leukaemia, 52 children with pre-B cell ALL, 1 child with B-cell acute lymphoblastic leukaemia and 9 children with T-cell acute lymphoblastic leukaemia. Haemorrhagic diathesis. splenomegaly, enlargement of peripheral lymph nodes as well as higher values of white blood cells count, blasts count, haemoglobin concentration, haematocrit and LDH activity were observed more frequently in patients with T-cell leukaemia than in others.
Zapolska
Beata
B
Klinika Onkologii Dzieciecej, Akademia Medyczna, ul. Waszyngtona 17, 15-274 Białystok, Poland.
Krawczuk-Rybak
Maryna
M
Łuczyński
Włodzimierz
W
Zak
Janusz
J
Leszczyńska
Elzbieta
E
D001772:Blood Cell Count; D002051:Burkitt Lymphoma / Q000175:diagnosis / Q000276:immunology; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins; D006474:Hemorrhagic Disorders / Q000209:etiology; D006801:Humans; D016130:Immunophenotyping; D007770:L-Lactate Dehydrogenase / Q000097:blood; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000175:diagnosis / Q000276:immunology; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood / Q000175:diagnosis* / Q000276:immunology*; D013163:Splenomegaly / Q000209:etiology
D006454:Hemoglobins; D007770:L-Lactate Dehydrogenase