Update on Hepatitis B and C Coinfection in HIV.
Coinfection with hepatitis B virus (HBV) or hepatitis C virus (HCV) is common in patients with HIV infection. HIV infection and immunosuppression alter the natural history of chronic viral hepatitis, and some patients experience accelerated progression to clinically significant liver disease. Therapies used in the treatment of HBV or HCV monoinfection have been applied to the treatment of HIV-coinfected patients. However, development of viral resistance and lack of virologic response remain significant areas of concern. Timely diagnosis and clinical staging of chronic hepatitis infection are critical in the management of HIV-coinfected patients.
Yachimski
Patrick
P
GRJ 825, GI Unit, Massachusetts General Hospital, Boston, MA 02114, USA. rtchung@partners.org.
Chung
Raymond T
RT