Characterisation of variant alleles in the STR systems D2S1338, D3S1358 and D19S433.
We have observed three hitherto undescribed off-ladder alleles at three widely used STR loci. These were isolated, sequenced and designated as follows: allele 10 (D2S1338, one case), allele 21 (D3S1358, two cases) and allele 6.2 (D19S433, six cases). These sequences are described in comparison to non-variant alleles, and their implications for the semi-automated STR analysis will be discussed.
Heinrich
Marielle
M
Institut für Rechtsmedizin, Universitätsklinikum Münster, Röntgenstr. 23, 48149 Münster, Germany.
Felske-Zech
Heike
H
Brinkmann
Bernd
B
Hohoff
Carsten
C
D000483:Alleles; D001483:Base Sequence; D006801:Humans; D017422:Sequence Analysis, DNA; D020080:Tandem Repeat Sequences / Q000235:genetics*