[Relationship between donor renal graft quality and graft rejection].
OBJECTIVE
To evaluate the correlation between the quality of donor renal grafts and graft rejection.


METHODS
The cold ischemia time and the pathological findings by biopsies of the donor grafts in 87 cases were analyzed in conjunction with the occurrence of acute or chronic graft rejection after transplantation.


RESULTS
After transplantation, acute rejection occurred in 28 cases, in which 5 (17.8%) had adverse changes in the donor grafts; chronic allograft nephropathy developed in 13 cases, in which 6 (46.1%) had adverse changes in the donor grafts. By binary logistic regression analysis, the cold ischemia time and acute renal tubular injury were identified as the factors affecting acute graft rejection, and cold ischemia time and glomeruloserosis as the risk factors for chronic rejection.


CONCLUSIONS
High-quality donor kidney and minimization of the risk factors help reduce the occurrence of graft rejection after kidney transplantation.
Yu
Li-xin
LX
Department of Kidney Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. liuxy@fimmu.edu.cn
Zeng
Jing-hua
JH
Fu
Shao-jie
SJ
Miao
Yun
Y
Ye
Gui-rong
GR
DU
Zheng-ping
ZP
Han
Cong-xiang
CX
D000328:Adult; D005260:Female; D006084:Graft Rejection / Q000209:etiology*; D006801:Humans; D007668:Kidney / Q000473:pathology; D016030:Kidney Transplantation / Q000009:adverse effects*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D014019:Tissue Donors