title: Cochlear implantation for treatment-induced ototoxic deafness in Langerhans cell histiocytosis. A case report.
abstract: A case is presented where the authors carried out a cochlear implantation on a girl whose deafness was induced by cytostatic agents. The normally hearing child was diagnosed with Langerhans cell histiocytosis at the age of 3 years and received polychemotherapy for almost 2 years. By her 5th year, she started to develop a bilateral, progressive sensorineural hearing loss, necessitating a hearing aid in both ears. While her histiocytosis was cured, her hearing ultimately deteriorated to total deafness on the right and profound hearing loss on the left ear. After 3 years, her hearing aids no longer provided adequate hearing for the postlingually deafened girl. At the age of 14, a cochlear implantation was performed on her right ear with excellent results.
authors.affiliation: Clinic of Otorhinolaryngology and Head and Neck Surgery, University of Szeged Faculty of Medicine, Hungary. torky@freemail.hu
authors.forename: Attila
authors.initials: A
authors.lastname: Torkos
authors.forename: Jeno
authors.initials: J
authors.lastname: Czigner
authors.forename: József Géza
authors.initials: JG
authors.lastname: Kiss
authors.forename: Ferenc
authors.initials: F
authors.lastname: Tóth
authors.forename: Alice
authors.initials: A
authors.lastname: Szamosközi
authors.forename: József
authors.initials: J
authors.lastname: Jóri
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D019929:Cochlear Implantation; D003054:Cochlear Implants; D005260:Female; D006312:Hearing Loss, Bilateral / Q000139:chemically induced* / Q000601:surgery; D006319:Hearing Loss, Sensorineural / Q000139:chemically induced* / Q000601:surgery; D006646:Histiocytosis, Langerhans-Cell / Q000188:drug therapy*; D006801:Humans; D013067:Speech Perception; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome