[Study on the effect of qinggan jiangtang tablet in improving the insulin resistance in patients with multiple metabolic syndrome].
OBJECTIVE
To observe the effect of Qinggan Jiangtang tablet (QJT) in improving the insulin resistance (IR) in patients with multiple metabolic syndrome (MMS).


METHODS
Adopting randomized controlled double-blinded method, 60 patients with MMS were divided equally into two groups. The treated group was treated by oral taking of QJT 3 tabs, twice a day and the control group treated by oral taking of Glucophage 3 tabs, twice a day, the therapeutic course for both groups was 1 month, and the observation lasted for 2 successive courses.


RESULTS
After treatment, levels of blood glucose, fasting and postprandial blood glucose, C-peptide and IR were significantly reduced with markedly improvement of beta-cell function in both groups, the difference between the two groups showed no significance. Change of plasma level of free fatty acids before and after treatment in both groups was insignificant.


CONCLUSIONS
QJT has the effects on reducing blood glucose, blood lipids, blood pressure and IR and improving function of beta cells.
Wang
Yan-juan
YJ
Department of Endocrinology, the First Hospital Affiliated to Hunan College of TCM, Changsha. wyj5566@hotmail.com
Zhu
Wen-feng
WF
Wang
Xing-kuan
XK
D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007333:Insulin Resistance; D008297:Male; D024821:Metabolic Syndrome / Q000188:drug therapy*; D008687:Metformin / Q000627:therapeutic use; D008875:Middle Aged; D008517:Phytotherapy; D013607:Tablets
D004365:Drugs, Chinese Herbal; D007004:Hypoglycemic Agents; D013607:Tablets; D008687:Metformin