title: A total synthesis of (+/-)-alpha-cyclopiazonic acid using a cationic cascade.
abstract: The indolic terpene alkaloid alpha-cyclopiazonic acid has been prepared in 11 steps from indole-4-methanol; the key step is a carbocationic cascade, terminated by a 4-nitrosulfonamide group and initiated by benzylic carbocation formation directly from the intermediate , which gives the tetracyclic product in 74% yield.
authors.affiliation: School of Chemistry, Cardiff University, Main Building, UK.
authors.forename: Charlotte M
authors.initials: CM
authors.lastname: Haskins
authors.forename: David W
authors.initials: DW
authors.lastname: Knight
mesh_terms: D002412:Cations; D007211:Indoles / Q000138:chemical synthesis*
chemical_list: D002412:Cations; D007211:Indoles; C000543:cyclopiazonic acid