Quantification of cation-pi interactions in protein-ligand complexes: crystal-structure analysis of Factor Xa bound to a quaternary ammonium ion ligand.
Schärer
Kaspar
K
Laboratorium für Organische Chemie, ETH Hönggerberg, HCI, 8093 Zürich, Switzerland.
Morgenthaler
Martin
M
Paulini
Ralph
R
Obst-Sander
Ulrike
U
Banner
David W
DW
Schlatter
Daniel
D
Benz
Jörg
J
Stihle
Martine
M
Diederich
François
F
D001665:Binding Sites; D002412:Cations / Q000737:chemistry; D003198:Computer Simulation; D018360:Crystallography, X-Ray; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry; D015951:Factor Xa / Q000737:chemistry* / Q000378:metabolism; D008024:Ligands; D046911:Macromolecular Substances / Q000737:chemistry; D008954:Models, Biological; D008956:Models, Chemical; D008958:Models, Molecular; D015394:Molecular Structure; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D013917:Thrombin / Q000737:chemistry
D002412:Cations; D004791:Enzyme Inhibitors; D008024:Ligands; D046911:Macromolecular Substances; D000644:Quaternary Ammonium Compounds; D013917:Thrombin; D015951:Factor Xa