title: Asthma as a risk factor for respiratory complications after adenotonsillectomy in children with obstructive breathing during sleep.
abstract: BACKGROUND
  Children with asthma are at increased risk for obstructive breathing during sleep. Adenotonsillectomy, the treatment of choice for obstructive breathing during sleep, is associated with significant postoperative respiratory morbidity.
  
  
  OBJECTIVE
  To determine whether asthma is a risk factor for respiratory complications after adenotonsillectomy in children with obstructive breathing during sleep.
  
  
  METHODS
  This case-control study compared 115 children aged 3 to 18 years with respiratory complications after adenotonsillectomy (study group) with 115 children without respiratory complications after adenotonsillectomy (control group).
  
  
  RESULTS
  The postoperative respiratory complications ranged from oxygen desaturation to respiratory failure that required mechanical ventilation. The study group had a higher proportion of children with asthma (P < .01). Logistic regression analysis showed that asthma increases the odds of postoperative respiratory complications to 4.4 (95% confidence interval, 2.13-9.0), after controlling for age, weight greater than the 97th percentile for age, sex, race, and medical conditions other than asthma.
  
  
  CONCLUSIONS
  In children with obstructive breathing during sleep, the presence of asthma is associated with an increased risk of respiratory complications after adenotonsillectomy.
authors.affiliation: Department of Pulmonary Medicine, Cincinnati Children's Hospital, Cincinnati, Ohio 45229, USA. maninder.kalra@cchmc.org
authors.forename: Maninder
authors.initials: M
authors.lastname: Kalra
authors.forename: Ralph
authors.initials: R
authors.lastname: Buncher
authors.forename: Raouf S
authors.initials: RS
authors.lastname: Amin
mesh_terms: D000233:Adenoidectomy; D000293:Adolescent; D001249:Asthma / Q000150:complications* / Q000453:epidemiology; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006764:Hospitals, Community; D006782:Hospitals, Special; D006801:Humans; D008297:Male; D011183:Postoperative Complications; D015995:Prevalence; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000601:surgery*; D014068:Tonsillectomy; D014481:United States / Q000453:epidemiology