[A motif-based scanning approach for prediction of protein phosphorylation].
Scansite is a short linear motif-based scanning approach established in the latest two years. It's accessible over the World Wide Web and can be used to identify sequence motifs likely to be phosphorylated by specific protein kinases or likely to bind to specific protein domains such as 14-3-3, SH2 and SH3 domains. The usage and function of the potent approach were reviewed and compared with previously established tools for phosphorylation prediction. The facing problems and application outlook of Scansite in prediction of cell signaling networks within proteomes were also presented.
Tang
Ying
Y
Beijing Institute of Radiation Medicine, Beijing 100850, China.
Zhang
Ling-Qiang
LQ
He
Fu-Chu
FC
D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D016208:Databases, Factual; D020407:Internet; D008969:Molecular Sequence Data; D010766:Phosphorylation; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism; D015398:Signal Transduction
D011506:Proteins