Application of microarray-based technology to neuroblastoma.
In the past decade, microarray technology has become a major tool for high-throughput comprehensive analysis of gene expression, genotyping and re-sequencing applications. High-throughput microarrays are used for expression profiling analyses with the aims of gene or pathway discovery, tumor subclassification or relapse risk assessment. The introduction of microarray CGH provides a powerful tool to precisely detect and quantify genomic aberrations and map these directly onto the human genome. This review summarizes the current status of the application of microarray technology to neuroblastoma research.
Scaruffi
Paola
P
Unit of Translational Paediatric Oncology, National Institute for Cancer Research (IST), Genoa, Italy.
Valent
Alexander
A
Schramm
Alexander
A
Astrahantseff
Kathy
K
Eggert
Angelika
A
Tonini
Gian Paolo
GP
D006801:Humans; D009447:Neuroblastoma / Q000235:genetics*; D009693:Nucleic Acid Hybridization; D020411:Oligonucleotide Array Sequence Analysis