title: Does genetic counseling have any impact on management of breast cancer risk?
abstract: Despite there being an increasing literature on the impact of cancer genetic counseling on risk perception and mental health, there is a lack of data describing impact on risk management. Genetic counseling and testing for cancer predisposition genes aims to improve the future health of those at high risk through appropriate surveillance and screening. However, management of breast cancer risk in women with a family history of this disease is an area of controversy. Counseling services may recommend specific risk management options to women, who then rely on their local screening service to make provision. This study investigated the impact of genetic counseling on management of breast cancer risk in women attending Cancer Family Clinics. A total of 293 women attending four genetic clinics were enrolled. Rates of breast self-examination, clinical breast examination, mammography, biopsy, detected cancers, and other screenings were documented. Participants' perceived benefits and barriers to mammography were assessed along with cancer worry. Results show that rates of mammography, clinical breast examination, and breast self-examination were increased following clinic attendance (p < 0.001). Women in the under 35 age-group had limited access to screening. Rates for biopsy and detected cancers were low. Women reported positive attitudes to mammography, with few reported barriers. Contrary to previous studies, there was no evidence that anxiety about breast cancer impedes uptake of health surveillance methods. Genetic counseling had a positive impact on management of breast cancer risk. Whether this translates into future health gains remains to be established.
authors.affiliation: Royal Marsden NHS Foundation Trust Hospital, Sutton SM2 5PT, United Kingdom. Maggie.watson@rmh.nthames.nhs.uk
authors.forename: M
authors.initials: M
authors.lastname: Watson
authors.forename: K M
authors.initials: KM
authors.lastname: Kash
authors.forename: J
authors.initials: J
authors.lastname: Homewood
authors.forename: S
authors.initials: S
authors.lastname: Ebbs
authors.forename: V
authors.initials: V
authors.lastname: Murday
authors.forename: R
authors.initials: R
authors.lastname: Eeles
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis / Q000235:genetics*; D016504:Breast Self-Examination / Q000706:statistics & numerical data; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D008327:Mammography / Q000523:psychology / Q000706:statistics & numerical data; D008403:Mass Screening / Q000706:statistics & numerical data; D008875:Middle Aged; D010808:Physical Examination / Q000706:statistics & numerical data; D018570:Risk Assessment