title: Sweet syndrome associated with furosemide.
abstract: This case report describes a case of Sweet syndrome (SS) related to use of furosemide in a 46-year-old female who was admitted for treatment of congestive heart failure. Three days after administration of furosemide, the patient had a fever and a skin eruption appeared on her wrists, forearms, and legs. Biopsy of the skin lesion was consistent with SS. Infection was thought to be unlikely because of negative blood cultures, echocardiography, and other imaging studies. Careful review of her medications revealed that the patient received furosemide before the appearance of the skin eruption and fever. After discontinuation of furosemide, the patient's skin lesion and fever resolved. A MEDLINE search from June 1966 to May 2004 revealed only one reference documenting the association of SS with furosemide administration. Patients who have development of SS without an obvious cause should have their medication list closely reviewed.
authors.affiliation: University of Missouri Health Science Center, Department of Internal Medicine, MA 406, One Hospital Drive, Columbia, MO 65212, USA. govindarajang@health.missouri.edu
authors.forename: Gurushankar
authors.initials: G
authors.lastname: Govindarajan
authors.forename: Qaiser
authors.initials: Q
authors.lastname: Bashir
authors.forename: Saravanan
authors.initials: S
authors.lastname: Kuppuswamy
authors.forename: Charles
authors.initials: C
authors.lastname: Brooks
mesh_terms: D004232:Diuretics / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D005665:Furosemide / Q000009:adverse effects*; D006333:Heart Failure / Q000188:drug therapy; D006801:Humans; D008875:Middle Aged; D016463:Sweet Syndrome / Q000139:chemically induced* / Q000473:pathology
chemical_list: D004232:Diuretics; D005665:Furosemide