title: High-energy phase-contrast X-ray imaging using a two-crystal X-ray interferometer.
abstract: To broaden the scope of phase-contrast X-ray imaging in biomedical applications, the energy of X-rays in a large-area imaging system using a two-crystal X-ray interferometer has been increased from 17.7 keV to 35 keV. The use of higher-energy X-rays makes it possible to observe larger samples having greater variation in density within shorter measurement periods, at higher spatial resolution, and at lower X-ray doses. After optimizing the imaging system for 35 keV X-rays, a 25 mm x 30 mm interference pattern with 50% visibility was generated at the Photon Factory. The system's capabilities are demonstrated by this pattern and a high-quality three-dimensional image of a rat heart.
authors.affiliation: Advanced Research Laboratory, Hitachi Ltd, Hatoyama, Saitama 350-0395, Japan. a-yoneya@rd.hitachi.co.jp
authors.forename: Akio
authors.initials: A
authors.lastname: Yoneyama
authors.forename: Tohoru
authors.initials: T
authors.lastname: Takeda
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Tsuchiya
authors.forename: Jin
authors.initials: J
authors.lastname: Wu
authors.forename: Thet Thet
authors.initials: TT
authors.lastname: Lwin
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Hyodo
authors.forename: Yasuharu
authors.initials: Y
authors.lastname: Hirai
mesh_terms: D000818:Animals; D006321:Heart / Q000000981:diagnostic imaging*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008857:Microscopy, Interference / Q000379:methods; D008858:Microscopy, Phase-Contrast / Q000379:methods*; D019047:Phantoms, Imaging; D011856:Radiographic Image Enhancement / Q000379:methods*; D051381:Rats; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014961:X-Ray Diffraction / Q000379:methods*