title: Risk factors for disease progression in patients with lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH): a systematic analysis of expert opinion.
abstract: Disease progression has become an important issue for the management of lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH). Although several risk factors have been identified, no specific patient risk profiles have been established that can be useful in the day-to-day management of LUTS/BPH. In this study, an international panel of urologists developed a risk classification based on the attribution of a risk score to 243 unique patient profiles. From the perspective of clinical decision making, it was concluded that postvoid residual, symptom severity and maximum flow rate are the most relevant determinants of the risk of disease progression.
authors.affiliation: 1St Luke's-Roosevelt Hospital Center, New York, NY 10019, USA. fclowemd@aol.com
authors.forename: F C
authors.initials: FC
authors.lastname: Lowe
authors.forename: J
authors.initials: J
authors.lastname: Batista
authors.forename: R
authors.initials: R
authors.lastname: Berges
authors.forename: E
authors.initials: E
authors.lastname: Chartier-Kastler
authors.forename: G
authors.initials: G
authors.lastname: Conti
authors.forename: F
authors.initials: F
authors.lastname: Desgrandchamps
authors.forename: K
authors.initials: K
authors.lastname: Dreikorn
authors.forename: M
authors.initials: M
authors.lastname: O'Leary
authors.forename: M
authors.initials: M
authors.lastname: Perez
authors.forename: M
authors.initials: M
authors.lastname: Speakman
authors.forename: J
authors.initials: J
authors.lastname: Trachtenberg
authors.forename: A
authors.initials: A
authors.lastname: Tubaro
authors.forename: B
authors.initials: B
authors.lastname: Meesen
authors.forename: L
authors.initials: L
authors.lastname: Smets
authors.forename: H
authors.initials: H
authors.lastname: Stoevelaar
mesh_terms: D018450:Disease Progression; D006801:Humans; D016015:Logistic Models; D008297:Male; D011336:Probability; D011379:Prognosis; D017430:Prostate-Specific Antigen / Q000096:biosynthesis; D011470:Prostatic Hyperplasia / Q000150:complications / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000150:complications / Q000453:epidemiology / Q000473:pathology*; D012306:Risk; D012307:Risk Factors; D014570:Urologic Diseases / Q000150:complications / Q000378:metabolism / Q000473:pathology*
chemical_list: D017430:Prostate-Specific Antigen