Side effects of combined therapy of methylprednisolone and intravenous immunoglobulin in Guillain-Barré syndrome.
Side effects were compared in 9 patients with Guillain-Barré syndrome treated with standard intravenous immunoglobulin (IVIg) only and in 9 treated with combined methylprednisolone and IVIg therapy. Headache occurred in 2 in both groups, indicative that pre-infusion with steroids does not prevent headache. Transient liver function disturbances were present in 2 patients of the former group and in 6 of the latter.
Odaka
M
M
Department of Neurology, Dokkyo University School of Medicine, Tochigi, Japan. m-odaka@dokkyomed.ac.jp
Tatsumoto
M
M
Hoshiyama
E
E
Hirata
K
K
Yuki
N
N
D000328:Adult; D000368:Aged; D018826:CD13 Antigens / Q000097:blood; D016022:Case-Control Studies; D004359:Drug Therapy, Combination; D005260:Female; D020275:Guillain-Barre Syndrome / Q000097:blood / Q000188:drug therapy; D006261:Headache / Q000209:etiology*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects*; D008107:Liver Diseases / Q000209:etiology*; D008297:Male; D008775:Methylprednisolone / Q000009:adverse effects*; D008875:Middle Aged; D018696:Neuroprotective Agents / Q000009:adverse effects*; D013997:Time Factors; D005723:gamma-Glutamyltransferase / Q000097:blood
D016756:Immunoglobulins, Intravenous; D018696:Neuroprotective Agents; D005723:gamma-Glutamyltransferase; D018826:CD13 Antigens; D008775:Methylprednisolone