title: Invited review: Bovine milk fat globule membrane as a potential nutraceutical.
abstract: For the last 15 yr, a great deal of knowledge has been accumulated on health beneficial factors, protein and nonprotein, of bovine milk fat globule membrane (MFGM). Among the health-beneficial components of the MFGM are cholesterolemia-lowering factor, inhibitors of cancer cell growth, vitamin binders, inhibitor of Helicobacter pylori, inhibitor of beta-glucuronidase of the intestinal Escherichia coli, xanthine oxidase as a bactericidal agent, butyrophilin as a possible suppressor of multiple sclerosis, and phospholipids as agents against colon cancer, gastrointestinal pathogens, Alzheimer's disease, depression, and stress. All of the above compel us to consider bovine MFGM as a potential nutraceutical.
authors.affiliation: BioVita Technologies, Bat Yam, Israel. vspits20@hotmail.com
authors.forename: V L
authors.initials: VL
authors.lastname: Spitsberg
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents; D000924:Anticholesteremic Agents; D001943:Breast Neoplasms / Q000517:prevention & control; D000071797:Butyrophilins; D002417:Cattle; D003327:Coronary Disease / Q000517:prevention & control; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000517:prevention & control; D006017:Glycolipids / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use*; D006023:Glycoproteins / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use*; D006293:Health Promotion; D016481:Helicobacter Infections / Q000517:prevention & control; D016480:Helicobacter pylori; D006801:Humans; D066292:Lipid Droplets; D008562:Membrane Glycoproteins / Q000008:administration & dosage; D009369:Neoplasms / Q000517:prevention & control; D009747:Nutritional Physiological Phenomena; D010743:Phospholipids / Q000008:administration & dosage
chemical_list: D000890:Anti-Infective Agents; D000924:Anticholesteremic Agents; D000071797:Butyrophilins; D006017:Glycolipids; D006023:Glycoproteins; D008562:Membrane Glycoproteins; D010743:Phospholipids; C110367:milk fat globule