Discordant molecular characterization results in a Mycobacterium avium complex strain isolated from an AIDS patient.
This report describes an unusual strain of Mycobacterium avium complex isolated from the sputum of an immunocompromised AIDS patient, which did not react with the MAC probe of the BDProbe Tec system, but was identified as Mycobacterium intracellulare by 16S rRNA gene sequencing. Its PCR restriction-enzyme analysis pattern was compatible with an allelic variant of M. avium. It was scotochromogenic, slow-growing and phenotypically identified as Mycobacterium scrofulaceum. Its clinical significance is not certain.
Huang
Tsi-Shu
TS
Section of Microbiology and Infectious Diseases, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Rd, Kaohsiung, Taiwan 2Department of Medical Technology, Foo-Yin Institute of Technology, Kaohsiung County, Taiwan 3Graduate Institute of Environmental Education, National Kaohsiung Normal University, Kaohsiung County, Taiwan 4Dept of Internal Medicine, National Yang-Ming University, Taipei, Taiwan.
Lee
Susan Shin-Jung
SS
Section of Microbiology and Infectious Diseases, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Rd, Kaohsiung, Taiwan 2Department of Medical Technology, Foo-Yin Institute of Technology, Kaohsiung County, Taiwan 3Graduate Institute of Environmental Education, National Kaohsiung Normal University, Kaohsiung County, Taiwan 4Dept of Internal Medicine, National Yang-Ming University, Taipei, Taiwan.
Chen
Yao-Shen
YS
Section of Microbiology and Infectious Diseases, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Rd, Kaohsiung, Taiwan 2Department of Medical Technology, Foo-Yin Institute of Technology, Kaohsiung County, Taiwan 3Graduate Institute of Environmental Education, National Kaohsiung Normal University, Kaohsiung County, Taiwan 4Dept of Internal Medicine, National Yang-Ming University, Taipei, Taiwan.
Tu
Hui-Zin
HZ
Section of Microbiology and Infectious Diseases, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Rd, Kaohsiung, Taiwan 2Department of Medical Technology, Foo-Yin Institute of Technology, Kaohsiung County, Taiwan 3Graduate Institute of Environmental Education, National Kaohsiung Normal University, Kaohsiung County, Taiwan 4Dept of Internal Medicine, National Yang-Ming University, Taipei, Taiwan.
Huang
Wen-Kuei
WK
Section of Microbiology and Infectious Diseases, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Rd, Kaohsiung, Taiwan 2Department of Medical Technology, Foo-Yin Institute of Technology, Kaohsiung County, Taiwan 3Graduate Institute of Environmental Education, National Kaohsiung Normal University, Kaohsiung County, Taiwan 4Dept of Internal Medicine, National Yang-Ming University, Taipei, Taiwan.
Liu
Yung-Ching
YC
Section of Microbiology and Infectious Diseases, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Rd, Kaohsiung, Taiwan 2Department of Medical Technology, Foo-Yin Institute of Technology, Kaohsiung County, Taiwan 3Graduate Institute of Environmental Education, National Kaohsiung Normal University, Kaohsiung County, Taiwan 4Dept of Internal Medicine, National Yang-Ming University, Taipei, Taiwan.
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000382:microbiology; D000328:Adult; D004269:DNA, Bacterial / Q000737:chemistry; D004275:DNA, Ribosomal / Q000737:chemistry; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D015269:Mycobacterium avium Complex / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D015270:Mycobacterium avium-intracellulare Infection / Q000175:diagnosis / Q000382:microbiology*; D015359:Mycobacterium scrofulaceum / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D010641:Phenotype; D016133:Polymerase Chain Reaction; D012329:RNA, Bacterial / Q000235:genetics; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D015183:Restriction Mapping; D013183:Sputum / Q000382:microbiology
D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012329:RNA, Bacterial; D012336:RNA, Ribosomal, 16S