title: Management of pellucid marginal corneal degeneration.
abstract: OBJECTIVE
  This study was designed to determine how patients with pellucid marginal corneal degeneration (PMCD) are managed in a tertiary corneal practice.
  
  
  METHODS
  A retrospective chart review of 45 patients with PMCD from a corneal referral practice was performed. Information collected from the medical records included demographic data, best-corrected visual acuity, videokeratography, contact lens use, and surgical procedures.
  
  
  RESULTS
  Forty-five patients (85 eyes; 30 males, 15 females) with PMCD were included in this study. They were followed-up for an average of 4.7 years (standard deviation (SD), +/-8.7). Seventy-five eyes (88.2%) were managed nonsurgically with spectacles in 31 eyes (36.4%) or contact lenses in 44 eyes (51.8%). Contact lens management was initially attempted in 51 eyes (60%); however, 7 eyes failed contact lenses. Visual acuity of 0.5 (20/40) or better was noted in 34 eyes (75.5%) after contact lens fit. Ten eyes (11.8%) underwent penetrating keratoplasty with an average postoperative follow-up of 9 years (SD, +/-8.2; 1.5-20.5). Clear grafts were present in all 10 eyes at the end of the study (average, 9 years; SD, +/-82).
  
  
  CONCLUSIONS
  Nonsurgical management of PMCD continues to play a predominant role in the management of this disorder. Poor best-corrected visual acuity at presentation of 0.2 (20/100) or worse and long follow-up (8 years or more) were significantly associated with surgery.
authors.affiliation: Cornea Service, Wills Eye Hospital, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA 19107, USA.
authors.forename: Patrick F
authors.initials: PF
authors.lastname: Tzelikis
authors.forename: Elisabeth J
authors.initials: EJ
authors.lastname: Cohen
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Rapuano
authors.forename: Kristin M
authors.initials: KM
authors.lastname: Hammersmith
authors.forename: Peter R
authors.initials: PR
authors.lastname: Laibson
mesh_terms: D000328:Adult; D000368:Aged; D003261:Contact Lenses; D003317:Corneal Dystrophies, Hereditary / Q000628:therapy*; D019781:Corneal Topography; D005139:Eyeglasses; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015948:Keratoplasty, Penetrating; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology