[Heart failure in hypertension in the elderly].
Incidence and prevalence of heart failure, in the form of systolic or diastolic ventricular dysfunction, are particularly common in elderly patients with hypertension. The importance of treating hypertension in the elderly as a means of preventing chronic heart failure was emphasized by recent trials including meta-analysis. Fastidious blood pressure control by angiotensin-converting enzyme inhibitors and angiotensin-II receptor antagonists along with low-doses diuretics as first-line therapy is recommended. However, many elderly patients with hypertension have other risk factors, target organ damages and associated cardiovascular conditions, to which the choice of the first drug should be tailored. In such cases, beta blockers, aldosterone blockers and long-acting Ca antagonists are also recommended.
Seto
Shinji
S
Department of Cardiovascular Medicine, Course of Medical and Dental Sciences, Graduate School of Biomedical Sciences, Nagasaki University.
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000368:Aged; D047228:Angiotensin II Type 1 Receptor Blockers / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D004232:Diuretics / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006333:Heart Failure / Q000188:drug therapy* / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy* / Q000503:physiopathology; D015201:Meta-Analysis as Topic; D012307:Risk Factors
D000319:Adrenergic beta-Antagonists; D047228:Angiotensin II Type 1 Receptor Blockers; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D004232:Diuretics