[Incidental carcinoma of the prostate: can we and should we recommend radical prostatectomy?].
BACKGROUND
There is controversy regarding tumor control of incidental prostate cancer (PC). We evaluated in a large cohort if we can recommend radical prostatectomy after TURP.


METHODS
In 52 (4.3%) from a total of 1207 patients undergoing radical prostatectomy the diagnosis had been made by TURP. In a retrospective analysis we evaluated morbidity, histopathological results, and tumor control of pT1a/b tumors.


RESULTS
The number of incidentally detected PC decreased with time. In 5.8% in the TURP group and in 0.5% of the needle biopsy group, there was no residual tumor found (p<0.001). Morbidity was similar +/- TURP with the exception of operation time (206 vs 188 min) and catheter duration (19.3 vs 17.3 days). Postoperative continence was identical. There was no difference in tumor control for local recurrence-free survival and PSA-free survival with and without TURP.


CONCLUSIONS
The rate of incidentally detected PC by TURP decreases over time, but in almost all cases we found clinically relevant cancer. TURP is not an adverse prognostic factor and morbidity is similar compared with patients who were diagnosed by needle biopsy. Our data confirm that we should recommend radical prostatectomy to patients who are candidates for further curative therapy.
Paul
R
R
Urologische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität, München. R.Paul@lrz.tu-muenchen.de
Knebel
C
C
van Randenborgh
H
H
Kübler
H
H
Alschibaja
M
M
Günther
M
M
Hartung
R
R
D000368:Aged; D005858:Germany / Q000453:epidemiology; D006801:Humans; D033162:Incidental Findings; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000401:mortality* / Q000473:pathology / Q000517:prevention & control*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D015995:Prevalence; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D016019:Survival Analysis; D015996:Survival Rate; D020728:Transurethral Resection of Prostate / Q000379:methods / Q000706:statistics & numerical data*; D016896:Treatment Outcome