Successful outpatient treatment of sinusitis exacerbations caused by community-acquired methicillin-resistant Staphylococcus aureus.
OBJECTIVE
To determine whether community-acquired MRSA sinusitis can be adequately treated on an outpatient basis without the need for intravenous antibiotics.


METHODS
Retrospective review of all cases of community-acquired MRSA sinusitis encountered by the author over a 36-month period.


RESULTS
Of 29 patients who tested positive for MRSA sinusitis, 26 patients had follow-up information available and were retrospectively reviewed. The average follow-up period was 12.0 months (range: 1-36 mo). Twelve infectious episodes of MRSA were treated with oral antibiotics alone and 16 were treated with a combination of oral and topical antibiotics. The mean time to clinical resolution with these regimens was 5.7 weeks (range: 3-8 wks). Two patients experienced recurrent MRSA infections resulting in a recurrence rate of 7.7% and an overall resolution rate of 92.3%.


CONCLUSIONS
Community-acquired MRSA sinusitis can be very adequately treated on an outpatient basis with culture-directed oral and topical antibiotics.
Gerencer
Roland Z
RZ
snot.doc@comcast.net
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D017714:Community-Acquired Infections; D004724:Endoscopy; D005260:Female; D006801:Humans; D016106:Methicillin Resistance; D008875:Middle Aged; D012008:Recurrence; D012852:Sinusitis / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery; D013203:Staphylococcal Infections / Q000188:drug therapy*