Experience of percutaneous coronary intervention in the management of pediatric cardiac allograft vasculopathy.
In a retrospective study, we examined the procedural success rate and the short-, intermediate-, and long-term outcomes of coronary interventional procedures in children with cardiac allograft vasculopathy. Seven patients underwent 13 interventional procedures: balloon angioplasty alone (n = 3), angioplasty with stenting (n = 9), or angioplasty with brachytherapy (n = 1), with procedural success in all. Two major complications (cardiac arrest) and a single death occurred in the immediate postprocedural period. Five (83%) of the remaining 6 patients developed moderate to severe restenosis, diffuse disease, or progressive vasculopathy; 3 have been retransplanted, 1 died from progressive cardiac allograft vasculopathy, and 1 is awaiting retransplantation, 40 months after the procedure.
Tham
Edythe B C
EB
Division of Pediatric Cardiology at Lucile Packard Children's Hospital, Stanford University, Stanford, California, USA.
Yeung
Alan C
AC
Cheng
Cheung Wah Boron
CW
Bernstein
Daniel
D
Chin
Clifford
C
Feinstein
Jeffrey A
JA
D000293:Adolescent; D015906:Angioplasty, Balloon, Coronary; D001918:Brachytherapy; D002648:Child; D002675:Child, Preschool; D023921:Coronary Stenosis / Q000209:etiology* / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome