title: Nonvitrectomizing vitreous surgery for epiretinal membrane long-term follow-up.
abstract: OBJECTIVE
  To report the long-term follow-up results of nonvitrectomizing vitreous surgery for idiopathic epiretinal membrane (ERM).
  
  
  METHODS
  Nonrandomized comparative case series.
  
  
  METHODS
  Thirty patients were followed up for at least 5 years after nonvitrectomizing vitreous surgery.
  
  
  METHODS
  Epiretinal membranes were peeled without infusion of balanced salt solution and removal of the vitreous. The data from the fellow eye was the control data.
  
  
  METHODS
  We examined the visual acuities (VAs), objective refractions, and slit-lamp and Scheimpflug photographs from the preoperative and the final examinations of both eyes. Quantitative assessment of the progression of nuclear sclerosis was performed by densitometry analysis using Scheimpflug photography. The recurrence rate of ERM was determined.
  
  
  RESULTS
  The follow-up periods ranged from 60 to 102 months (mean+/-standard deviation, 72.2+/-11.0 months). The patient ages ranged from 52 to 76 years (68.8+/-6.3 years). The final VA improved or stabilized within 2 lines in 29 of 30 eyes (96.7%). No unilateral progression of nuclear sclerosis occurred in any cases. The mean preoperative and postoperative refractions without additional surgery were -0.4+/-2.9 diopters (D) and -0.2+/-3.0 D in the operated eyes, respectively, and -0.2+/-2.5 D and 0.1+/-2.4 D, respectively, in the unoperated fellow eyes. The mean differences in the refractive error between both eyes (operated eye data minus fellow eye data) were -0.2+/-0.7 D before surgery and -0.3+/-0.8 D after surgery (P = 0.319, paired t test). The mean preoperative and postoperative nuclear densities in 16 patients were 69+/-14 nuclear density units (NDUs) and 76+/-12 NDUs in the operated eyes and 71+/-14 NDUs and 78+/-14 NDUs in the fellow eyes, respectively. The mean preoperative and postoperative differences in nuclear densities in both eyes were -2+/-2 NDUs and -2+/-5 NDUs, respectively (P = 0.836, paired t test). The ERM recurred in 10 eyes (33%), and 3 eyes underwent conventional vitrectomy combined with cataract surgery.
  
  
  CONCLUSIONS
  Unilateral nuclear sclerosis did not progress for at least 5 years after nonvitrectomizing vitreous surgery. The recurrence rate of ERM appeared to be higher than that after conventional vitreous surgery.
authors.affiliation: Department of Ophthalmology, Osaka University Medical School, Suita, Osaka, Japan. sawamiki@ophthal.med.osaka-u.ac.jp
authors.forename: Miki
authors.initials: M
authors.lastname: Sawa
authors.forename: Masahito
authors.initials: M
authors.lastname: Ohji
authors.forename: Shunji
authors.initials: S
authors.lastname: Kusaka
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Sakaguchi
authors.forename: Fumi
authors.initials: F
authors.lastname: Gomi
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Saito
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Tano
mesh_terms: D000368:Aged; D019773:Epiretinal Membrane / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007907:Lens Nucleus, Crystalline / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012598:Sclerosis / Q000517:prevention & control; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods*; D014822:Vitreous Body / Q000601:surgery*