The manifestation of AIDS in Africa: an epidemiological overview.
The HIV epidemic in Africa has changed over the last decade and the incidence of AIDS, which was very low at the beginning of nineties, is now dramatically increasing. In this paper, we analyze the current situation of AIDS epidemiology on the continent, based on data generated by the antenatal care surveillance systems. As described here, the spread and prevalence of HIV differ in each African country, with South Africa now facing the worst situation. In addition, we have focused our attention on the modes and risks of viral transmission, highlighting the spread of HIV in particular subpopulations, which, for different reasons, prove to be more affected by the epidemic, such as sex workers and children. Genotype evolution and distribution in the various geographical areas are also considered. From this brief overview, it appears clear that poverty, the lack of technologies and inadequate resources, due mostly to social and economic instability, are widening the already existent gap between Africa and industrialized countries.
Ferrante
Pasquale
P
University of Milan Laboratory of Biology, Don C. Gnocchi Foundation ONLUS, IRCCS, Milan, Italy. pferrante@dongnocchi.it
Delbue
Serena
S
Mancuso
Roberta
R
D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology*; D000349:Africa / Q000453:epidemiology; D002648:Child; D005260:Female; D005843:Geography; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000821:virology; D011295:Prenatal Care; D015995:Prevalence; D013019:South Africa / Q000453:epidemiology