title: Investigation of herpes simplex virus DNA in pityriasis rosea by polymerase chain reaction.
abstract: BACKGROUND
  Pityriasis rosea (PR) is an acute, inflammatory disease of unknown cause. Clinical and experimental findings indicate an infectious etiology of PR. Our purpose is to examine the skin lesions and blood samples of PR patients by polymerase chain reaction (PCR) for the presence of HSV type 1 and 2 DNA.
  
  
  METHODS
  The lesional skin biopsies from 10 patients and blood samples from two randomized patients with clinically and histologically confirmed pityriasis rosea were examined by PCR.
  
  
  RESULTS
  No HSV 1 and HSV 2 DNA was detected in the lesional biopsy and blood samples.
  
  
  CONCLUSIONS
  We could not identify a relationship between HSV 1, HSV 2 and PR.
authors.affiliation: Department of Dermatology, Atatürk Training and Research Hospital, Izmir, Turkey. bozdag@egenet.com.tr
authors.forename: Kübra Eren
authors.initials: KE
authors.lastname: Bozdag
authors.forename: Füsun Ozder
authors.initials: FO
authors.lastname: Güven
authors.forename: Aysin
authors.initials: A
authors.lastname: Zeytinoglu
authors.forename: Selda
authors.initials: S
authors.lastname: Erensoy
authors.forename: Ahmet
authors.initials: A
authors.lastname: Karaman
authors.forename: Altýnay
authors.initials: A
authors.lastname: Bilgiç
mesh_terms: D000328:Adult; D001706:Biopsy; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D018259:Herpesvirus 1, Human / Q000302:isolation & purification*; D018258:Herpesvirus 2, Human / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D017515:Pityriasis Rosea / Q000097:blood / Q000473:pathology / Q000821:virology*; D016133:Polymerase Chain Reaction; D012867:Skin / Q000473:pathology
chemical_list: D004279:DNA, Viral