title: [The meninges, an anatomical point of view].
abstract: The meninges correspond to an anatomical concept. For the morphologist, the microscopic organization, the hypothetical presence of a subdural space, the nature of the interface between the deep meningeal layer and the nervous parenchyma in the perivascular spaces are the central issues. For the clinician, dynamic aspects of cerebrospinal fluid flow, secretion, and resorption are essential factors with practical consequences in terms of disease and patient management. Comparative anatomy, embryology, and organogenesis provide an interesting perspective for the descriptive and functional anatomy of the meninges. Usually considered as protective membranes, the meninges play a prominent role in the development and maintenance of the central nervous system. The meninges are in constant evolution, from their formation to senescence. The meninges present three layers in children and adults: the dura mater, the arachnoid and the pia mater. The cerebrospinal fluid is secreted by the choroid plexuses, flows through the ventricles and the subarachnoid space, and is absorbed by arachnoid granulations. Other sites of secretion and resorption are suggested by comparative anatomy and human embryology and organogenesis.
authors.affiliation: Laboratoire d'Anatomie et Organogenèse, Faculté de Médecine, 28 Place Henri Dunant, BP 38, 63001 Clermont-Ferrand. lsakka@chu-clermontferrand.fr
authors.forename: L
authors.initials: L
authors.lastname: Sakka
authors.forename: J
authors.initials: J
authors.lastname: Chazal
mesh_terms: D000328:Adult; D000368:Aged; D002648:Child; D006801:Humans; D008578:Meninges / Q000033:anatomy & histology* / Q000196:embryology; D009024:Morphogenesis