The promise of cytokine antibody arrays in the drug discovery process.
The introduction of cytokine antibody arrays has added a new approach for investigators to simultaneously measure multiple cytokine levels in biological samples. Several different platforms have been developed. The ability to measure hundreds of cytokine levels with high specificity and sensitivity within a very limited amount of samples is a powerful tool. Many investigators worldwide have applied this novel technology in their biomedical research, particularly in drug discovery. Undoubtedly, the technology will continue to be improved and the application increased in the next several years.
Huang
Ruo-Pan
RP
Division of Research, Department of Gynecology and Obstetrics, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA. rhuang@emory.edu
Yang
Weimin
W
Yang
Dongzi
D
Flowers
Lisa
L
Horowitz
Ira R
IR
Cao
Xuan
X
Huang
Ruochun
R
D000906:Antibodies / Q000276:immunology*; D016207:Cytokines / Q000276:immunology / Q000378:metabolism*; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D040081:Protein Array Analysis / Q000379:methods*
D000906:Antibodies; D016207:Cytokines