[Natural killer cell leukemia. Case report].
Natural killer leukemia is a rare and highly aggressive neoplasm, is more common in young male patients and has a very poor prognosis, with a median survival of few weeks. We report a 17 years old male patient who developed, after an acute upper respiratory disease, a rapidly multiorganic failure with pancytopenia. Bone marrow aspiration and trephine biopsy showed an acute lymphoblastic leukemia. The immunophenotype and immunohistochemistry revealed a natural killer acute leukemia. The disease progressed rapidly and the patient died shortly after the diagnosis.
Guerrero A
Mario
M
Departamento de Hematología-Oncología, Pontificia Universidad Católica de Chile, Santiago, Chile. mariogacu@hotmail.com
Lira V
Pablo
P
Bertin C
Pablo
P
Galleguillos V
Mauricio
M
Ocqueteau T
Mauricio
M
D000293:Adolescent; D015703:Antigens, CD / Q000276:immunology; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D016130:Immunophenotyping; D007694:Killer Cells, Natural; D007938:Leukemia / Q000276:immunology / Q000473:pathology* / Q000628:therapy; D008297:Male
D015703:Antigens, CD