Polymerized vesicles containing molecular recognition sites.
Vesicles are prepared from diacetylenic peptide amphiphiles that expose a molecular recognition site at the surface. The amphiphiles can be polymerized using UV light, and the resulting polymeric vesicles exhibit interesting chromatic responses that can be used for label-free detection of the interaction with a distinct protein in solution.
Biesalski
Markus
M
Institute for Microsystem Technology (IMTEK), Department of Chemistry and Physics of Interfaces, University of Freiburg, 79085 Freiburg, Germany. biesalsk@imtek.de
Tu
Raymond
R
Tirrell
Matthew V
MV