title: Serological and virological features of dengue fever and dengue haemorrhagic fever in Thailand from 1999 to 2002.
abstract: Serological and virological features of dengue fever (DF) and dengue haemorrhagic fever (DHF) in Thailand were analysed in 2715 patients from 1999 to 2002. The illness was caused by DEN-1 in 45%, DEN-2 in 32%, DEN-3 in 18% and DEN-4 in 5% of patients. Almost all of the DHF cases caused by DEN-2 and DEN-4 were in secondary infection, while approximately 20% of the DHF cases caused by DEN-1 and DEN-3 were in primary infection. Male:female ratio and age distribution were not different among four serotypes in primary and secondary infections. These results indicate that DEN-1 and DEN-3 induce DHF in both primary and secondary infections, and suggest that DEN-2 and DEN-4 in Thailand are less likely to cause DHF in primary infections.
authors.affiliation: National Institute of Health, Department of Medical Sciences, Ministry of Public Health, 88/7, Tivanond Road, Muang, Nonthaburi, 11000, Thailand. surapee@dmsc.moph.go.th
authors.forename: S
authors.initials: S
authors.lastname: Anantapreecha
authors.forename: S
authors.initials: S
authors.lastname: Chanama
authors.forename: A
authors.initials: A
authors.lastname: A-nuegoonpipat
authors.forename: S
authors.initials: S
authors.lastname: Naemkhunthot
authors.forename: A
authors.initials: A
authors.lastname: Sa-Ngasang
authors.forename: P
authors.initials: P
authors.lastname: Sawanpanyalert
authors.forename: I
authors.initials: I
authors.lastname: Kurane
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003715:Dengue / Q000097:blood / Q000453:epidemiology* / Q000209:etiology / Q000821:virology; D003716:Dengue Virus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D012367:RNA, Viral / Q000032:analysis; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012307:Risk Factors; D012703:Serotyping; D019595:Severe Dengue / Q000097:blood / Q000453:epidemiology / Q000209:etiology / Q000821:virology; D013785:Thailand / Q000453:epidemiology
chemical_list: D012367:RNA, Viral