The rate of visual field loss in optic nerve head drusen.
OBJECTIVE
To define the rate of visual field loss in patients with optic nerve head drusen (ONHD).


METHODS
Retrospective chart review.


METHODS
Goldmann visual field (GVF) testing from initial visit and last follow-up examination were quantified using the modified Esterman grid technique. The rate of visual field loss was calculated by comparing the initial GVF to the last follow-up GVF. A comparative analysis of GVF and age at initial evaluation was performed on all patients with an initial GVF only.


METHODS
Tertiary academic care center.


METHODS
Inclusion criteria for the rate analysis: (1) diagnosis of ONHD and (2) at least 36 months of follow-up with serial GVF testing.


METHODS
(1) patients with glaucoma or glaucoma-suspect; (2) history or examination evidence for other ocular disease; and (3) drusen-related macular causes of visual loss.


RESULTS
Thirty-two of 292 charts were included in the rate analysis. The rate of visual field loss was 1.58%. There was no statistically significant difference between men and women (P = .74). One hundred eighty patients were included in the initial visual field analysis. There was a significant negative correlation between age and GVF, with older patients having lower GVF scores with a Spearman correlation of -0.42 (P < 0.0001); 73% of these 180 patients had mild, minimal, or no visual field loss.


CONCLUSIONS
The rate of visual field loss for ONHD over a 36-month interval of time was 1.6% per year. Patients with minimal or no visual field loss were younger, and patients with moderate or severe visual loss were older.
Lee
Andrew G
AG
Departments of Ophthalmology, Neurology, and Neurosurgery, the University of Iowa Hospitals and Clinics, 200 Hawkins Drive PFP, Iowa City, IA 52242, USA. andrew-lee@uiowa.edu
Zimmerman
M Bridget
MB
D000328:Adult; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000503:physiopathology*; D015594:Optic Disk Drusen / Q000175:diagnosis / Q000503:physiopathology*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014786:Vision Disorders / Q000503:physiopathology*; D014792:Visual Acuity; D014794:Visual Fields