title: [Analysis of heart rate variability in assessment of baroreflex sensitivity in anesthetized rats].
abstract: Spectral analysis of the heart rate variability can be used as a measure of baroreflex sensitivity in ketamine anesthetized rats. Stimulation of delta1-receptors with phenylephrine (0.01 mg/kg, i.v.) results in a rise of the strength of heart rate regulation, principally in the low frequency band. Maximal deviations of spectral indexes from basal level were observed on 4-8 min for low (0.2-1 Hz) and high (1-3 Hz) frequencies bands and on 10-15 min for very low (0.08-0.2 Hz) frequency band after phenylephrine injection.
authors.affiliation: Donetsk Medical University.
authors.forename: I A
authors.initials: IA
authors.lastname: Khripachenko
authors.forename: A V
authors.initials: AV
authors.lastname: Savust'ianenko
authors.forename: L A
authors.initials: LA
authors.lastname: Kedenko
authors.forename: I I
authors.initials: II
authors.lastname: Zinkovych
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000494:pharmacology; D000704:Analysis of Variance; D000758:Anesthesia; D000818:Animals; D017704:Baroreflex / Q000187:drug effects / Q000502:physiology*; D004562:Electrocardiography; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology*; D008297:Male; D009200:Myocardial Contraction / Q000187:drug effects / Q000502:physiology; D010656:Phenylephrine / Q000494:pharmacology; D051381:Rats
chemical_list: D000316:Adrenergic alpha-Agonists; D010656:Phenylephrine