title: A preventable illness? Purulent pericarditis due to Streptococcus pneumoniae complicated by haemolytic uraemic syndrome in an infant.
abstract: A previously healthy eight-month-old infant presented with shortness of breath and pyrexia. He was found to have purulent pericarditis due to Streptococcus pneumoniae, complicated by acute renal failure due to haemolytic uraemic syndrome. He received peritoneal dialysis and recovered with normalisation of renal function. This case highlights two important complications of pneumococcal infection in one individual and illustrates the need for rapid diagnosis and treatment of invasive pneumococcal disease. It is anticipated that introduction of the conjugate pneumococcal vaccination to the Australian Standard Vaccination Schedule from 2005 will reduce the incidence of pneumococcal infection and its associated morbidity and mortality.
authors.forename: Joanna H P
authors.initials: JH
authors.lastname: Yong
authors.forename: Bob K
authors.initials: BK
authors.lastname: Fonseca
authors.forename: Emma J
authors.initials: EJ
authors.lastname: Best
authors.forename: Tamsin
authors.initials: T
authors.lastname: Holland
authors.forename: Maria E
authors.initials: ME
authors.lastname: Craig
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology / Q000628:therapy; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002443:Ceftriaxone / Q000008:administration & dosage / Q000627:therapeutic use; D005500:Follow-Up Studies; D006463:Hemolytic-Uremic Syndrome / Q000150:complications* / Q000628:therapy; D006801:Humans; D007223:Infant; D008297:Male; D010493:Pericarditis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D010530:Peritoneal Dialysis; D011008:Pneumococcal Infections / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D013296:Streptococcus pneumoniae / Q000302:isolation & purification; D013492:Suppuration / Q000150:complications / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D002443:Ceftriaxone