title: Renal cell carcinoma with solitary toe metastasis.
abstract: Solitary metastases to the small bones and/or to the soft tissue of the hands and feet (acrometastases) are rare. We report a case of renal cell carcinoma (RCC) with big toe metastasis revealed before the primary tumor became apparent. The best treatment for a single metastasis is always surgical excision, regardless of the lesion being synchronous or metachronous. The biological behavior of metastatic RCC is unpredictable and only early diagnosis and treatment may favorably affect patient survival. Thus, metastatic RCC should be included in the differential diagnosis of all enlarging cutaneous nodules, wherever they develop.
authors.affiliation: Department of Urology, National Cancer Institute, I.R.C.C.S. Fondazione 'G.Pascale', Naples, Italy. s.perdona@libero.it
authors.forename: Sisto
authors.initials: S
authors.lastname: Perdonà
authors.forename: Riccardo
authors.initials: R
authors.lastname: Autorino
authors.forename: Luigi
authors.initials: L
authors.lastname: Gallo
authors.forename: Marco
authors.initials: M
authors.lastname: DE Sio
authors.forename: Luigi
authors.initials: L
authors.lastname: Marra
authors.forename: Luigi
authors.initials: L
authors.lastname: Claudio
authors.forename: Corrado
authors.initials: C
authors.lastname: Caracò
authors.forename: Renato
authors.initials: R
authors.lastname: Franco
authors.forename: Flavio
authors.initials: F
authors.lastname: Fazzioli
authors.forename: Antonio
authors.initials: A
authors.lastname: Gallo
mesh_terms: D000368:Aged; D000671:Amputation, Surgical; D001706:Biopsy; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000601:surgery; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging / Q000556:secondary* / Q000601:surgery; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008297:Male; D009392:Nephrectomy; D011859:Radiography; D014034:Toes