Hemichorea-hemiballismus may respond to topiramate.
Topiramate is a broad-spectrum anticonvulsant that is now widely used for adult and pediatric epilepsy. In a singular case, topiramate was recently reported to benefit vascular hemichorea-hemiballismus. The authors describe three cases of hemichorea-hemiballismus, one of vascular etiology and two of metabolic etiology, effectively treated with topiramate.
Driver-Dunckley
Erika
E
Department of Neurology, Mayo Clinic, Scottsdale, Arizona 85259, USA.
Evidente
Virgilio Gerald H
VG
D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use*; D002819:Chorea / Q000188:drug therapy* / Q000209:etiology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D020820:Dyskinesias / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005632:Fructose / Q000031:analogs & derivatives* / Q000627:therapeutic use; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D006943:Hyperglycemia / Q000150:complications; D008297:Male; D008875:Middle Aged; D020521:Stroke / Q000188:drug therapy; D000077236:Topiramate
D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose