title: Current status of proteomic standards development.
abstract: The generation of proteomic data is becoming ever more high throughput. Both the technologies and experimental designs used to generate and analyze data are becoming increasingly complex. The need for methods by which such data can be accurately described, stored and exchanged between experimenters and data repositories has been recognized. Work by the Proteome Standards Initiative of the Human Proteome Organization has laid the foundation for the development of standards by which experimental design can be described and data exchange facilitated. The Minimum Information About a Proteomic Experiment data model describes both the scope and purpose of a proteomics experiment and encompasses the development of more specific interchange formats such as the mzData model of mass spectrometry. The eXtensible Mark-up Language-MI data interchange format, which allows exchange of molecular interaction data, has already been published and major databases within this field are supplying data downloads in this format.
authors.affiliation: EMBL Outstation, European Bioinformatics Institute, Wellcome Trust, Genome Campus, Hinxton, Cambridge, UK. orchard@ebi.ac.uk
authors.forename: Sandra
authors.initials: S
authors.lastname: Orchard
authors.forename: Chris
authors.initials: C
authors.lastname: Taylor
authors.forename: Henning
authors.initials: H
authors.lastname: Hermjakob
authors.forename: Weimin
authors.initials: W
authors.lastname: Zhu
authors.forename: Randall
authors.initials: R
authors.lastname: Julian
authors.forename: Rolf
authors.initials: R
authors.lastname: Apweiler
mesh_terms: D030562:Databases, Protein; D006801:Humans; D013058:Mass Spectrometry; D020411:Oligonucleotide Array Sequence Analysis; D020543:Proteome / Q000235:genetics / Q000592:standards*; D040901:Proteomics / Q000379:methods* / Q000592:standards* / Q000639:trends; D012958:Societies, Scientific
chemical_list: D020543:Proteome