Community-acquired pneumonia by Legionella pneumophila serogroups 1-6 in Brazil.
A prospective cohort study of adult patients hospitalized due to community-acquired pneumonia was carried out for 1 year in a Brazilian university general hospital to detect the incidence of community-acquired pneumonia by Legionella pneumophila serogroups 1-6. During a whole year, a total of 645 consecutive patients who were hospitalized due to a initial presumptive diagnosis of respiratory disease by ICD-10 (J00-J99), excluding upper respiratory diseases, were screened to detect the patients with community-acquired pneumonia. Fifty-nine consecutive patients hospitalized due to community-acquired pneumonia between July 19, 2000 and July 18, 2001, were included in the study. They had determinations of serum antibodies to L. pneumophila serogroups 1-6 by indirect immunofluorescence antibody test at the Infectious Diseases Laboratory of University of Louisville (KY, USA) and urinary antigen tests for L. pneumophila serogroup 1. Three patients had community-acquired pneumonia by L. pneumophila serogroups 1-6, two patients being diagnosed by seroconversion and positive urinary antigen tests; the other had negative serologies but strongly positive urinary antigen test. The incidence of community-acquired pneumonia by L. pneumophila serogroups 1-6 in our hospital was 5.1%.
Chedid
Maria Bernadete F
MB
Pulmonology Service, Hospital de Clínicas, Federal University of Rio Grande do Sul, Brazil. mariab@terra.com.br
Ilha
Darcy de O
Dde O
Chedid
Marcio F
MF
Dalcin
Paulo R
PR
Buzzetti
Mary
M
Jaconi Saraiva
Paulo
P
Griza
Daniela
D
Menna Barreto
Sergio S
SS
D000293:Adolescent; D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000097:blood; D000942:Antigens, Bacterial / Q000652:urine; D001938:Brazil / Q000453:epidemiology; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology; D019084:Fluorescent Antibody Technique, Indirect; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D016952:Legionella pneumophila / Q000145:classification* / Q000276:immunology / Q000302:isolation & purification; D007877:Legionnaires' Disease / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000382:microbiology; D008875:Middle Aged; D018579:Patient Selection; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial