Chronic inflammatory demyelinating polyneuropathy and respiratory failure.
Neuromuscular respiratory failure is not considered to be a clinical feature of chronic inflammatory demyelinating polyneuropathy (CIDP). We present 4 patients with CIDP who required respiratory assistance and mechanical ventilation. Two patients needed emergent intubation and one patient lapsed in a stupor from hypercapnia. Respiratory failure in CIDP should be considered exceptional, but more formal studies in CIDP may be needed to assess its prevalence.
Henderson
Robert D
RD
Dept. of Neurology, Royal Brisbane & Women's Hospital, Brisbane, QLD, Australia.
Sandroni
Paola
P
Wijdicks
Eelco F M
EF
D000368:Aged; D001379:Azathioprine / Q000627:therapeutic use; D001706:Biopsy; D003128:Coma / Q000209:etiology; D003520:Cyclophosphamide / Q000627:therapeutic use; D004576:Electromyography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006935:Hypercapnia / Q000209:etiology; D007074:Immunoglobulin G; D016756:Immunoglobulins, Intravenous; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007440:Intubation; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction; D009468:Neuromuscular Diseases / Q000150:complications; D010956:Plasmapheresis; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D011241:Prednisone / Q000627:therapeutic use; D012008:Recurrence; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency / Q000473:pathology*; D013497:Sural Nerve / Q000473:pathology / Q000601:surgery; D013997:Time Factors; D014132:Trachea; D016896:Treatment Outcome
D007074:Immunoglobulin G; D016756:Immunoglobulins, Intravenous; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D001379:Azathioprine; D011241:Prednisone