Titanium-mediated [4 + 1] assembly of 1,3-dienes and nitriles: formation of 3-cyclopentenyl amines and cyclopentenones.
In the presence of Ti(OiPr)4 and iPrMgCl, dienes couple with nitriles to afford the title products in good yields.
Laroche
Christophe
C
UMR 6519 - Réactions Sélectives et Applications, CNRS - Université de Reims Champagne-Ardenne, BP 1039, 51687 REIMS Cedex 2, France.
Bertus
Philippe
P
Szymoniak
Jan
J