title: Technological issues for the development of more efficient calcium phosphate bone cements: a critical assessment.
abstract: The first calcium phosphate cements (CPCs) were discovered in the 1980s. Two decades later, the interest for these materials is still rising. The goal of the present document is to review the most recent achievements in the field and to analyze future directions in research and development.
authors.affiliation: Dr Robert Mathys Foundation, Bischmattstrasse 12, CH-2544 Bettlach, Switzerland. Mec.bohner@rms-foundation.ch
authors.forename: M
authors.initials: M
authors.lastname: Bohner
authors.forename: U
authors.initials: U
authors.lastname: Gbureck
authors.forename: J E
authors.initials: JE
authors.lastname: Barralet
mesh_terms: D020341:Absorbable Implants; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D001843:Bone Cements / Q000737:chemistry*; D001861:Bone Regeneration; D018786:Bone Substitutes; D002130:Calcium Phosphates / Q000737:chemistry*; D016503:Drug Delivery Systems; D006801:Humans; D020007:Implants, Experimental; D008422:Materials Testing; D013997:Time Factors
chemical_list: D001672:Biocompatible Materials; D001843:Bone Cements; D018786:Bone Substitutes; D002130:Calcium Phosphates; C020243:calcium phosphate