Predicting the effect of post-implant cochlear fibrosis on residual hearing.
Intracochlear scarring is a well-described sequela of cochlear implantation. We developed a mathematical model of passive cochlear mechanics to predict the impact that this might have upon residual acoustical hearing after implantation. The cochlea was modeled using lumped impedance terms for scala vestibuli (SV), scala tympani (ST), and the cochlear partition (CP). The damping of ST and CP was increased in the basal one half of the cochlea to simulate the effect of scar tissue. We found that increasing the damping of the ST predominantly reduced basilar membrane vibrations in the apex of the cochlea while increasing the damping of the CP predominantly reduced basilar membrane vibrations in the base of the cochlea. As long as intracochlear scarring continues to occur with cochlear implantation, there will be limitations on hearing preservation. Newer surgical techniques and electrode technologies that do not result in as much scar tissue formation will permit improved hearing preservation.
Choi
Chul-Hee
CH
Bobby R. Alford Department of Otolaryngology, Head and Neck Surgery, Baylor College of Medicine, Houston, TX 77030, USA. cchoi@bcm.tmc.edu
Oghalai
John S
JS
D000818:Animals; D002415:Cats; D002921:Cicatrix / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D003051:Cochlea / Q000473:pathology* / Q000503:physiopathology; D019929:Cochlear Implantation / Q000009:adverse effects*; D003054:Cochlear Implants; D003198:Computer Simulation; D003638:Deafness / Q000534:rehabilitation; D017097:Electric Impedance; D005355:Fibrosis; D006309:Hearing / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D011183:Postoperative Complications / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D012533:Scala Tympani / Q000473:pathology / Q000503:physiopathology