title: Sonographic features of lethal multiple pterygium syndrome at 14 weeks.
abstract: Lethal multiple pterygium syndrome is a rare inherited disorder. Previous reports suggest that the diagnosis may be based on prenatal sonographic demonstration of severe limb flexion, absence of fetal motion, and a large cystic hygroma in the second and third trimesters. We present the sonographic features and postmortem features of a fetus with lethal multiple pterygium syndrome at 13 weeks of gestation, which shows that the condition can possibly be diagnosed in the first trimester of pregnancy.
authors.affiliation: Prenatal Diagnostic and Counseling Unit, Department of Obstetrics and Gynaecology, Tsan Yuk Hospital, Sai Ying Pun, Hong Kong, PR China. chenm@hkusua.hku.hk
authors.forename: Min
authors.initials: M
authors.lastname: Chen
authors.forename: Gavin Shueng Wai
authors.initials: GS
authors.lastname: Chan
authors.forename: Chin Peng
authors.initials: CP
authors.lastname: Lee
authors.forename: Mary Hoi Yin
authors.initials: MH
authors.lastname: Tang
mesh_terms: D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging* / Q000473:pathology; D000328:Adult; D001201:Ascites / Q000000981:diagnostic imaging; D004487:Edema / Q000000981:diagnostic imaging; D005260:Female; D005324:Fetal Movement; D005865:Gestational Age; D006801:Humans; D018191:Lymphangioma, Cystic / Q000000981:diagnostic imaging; D011247:Pregnancy; D013577:Syndrome; D016216:Ultrasonography, Prenatal