[Interdigitating dendritic cell sarcoma-a case report with literature review].
OBJECTIVE
To report a case of interdigitating dendritic cell sarcoma (IDCS).


METHODS
The patient was a 41-year-old man with a lymph node bulging in the left neck. Laboratory examination of peripheral blood and bone marrow was abnormal. The diagnosis of IDCS was made by immunohistochemistry and electron microscopy. Treatment of this patient with ABVD regimen (adriamycin, bleomycin, vinblastine, dacarbazine) resulted in obvious improvement, but did not control the tumor infiltration.


CONCLUSIONS
IDCS has no distinctive clinical or pathohistological characteristics. Immunohistochemistry and electron microscopy are crucial in distinguishing it from other histiocytic/dendritic cell neoplasms. IDCS displays an aggressive behaviour, and the responses to chemotherapy are variable.
Gao
Wen-Jin
WJ
Jiangsu Institute of Hematology, First Affiliated Hospital, Suzhou University, Suzhou 215006, China.
Zhang
Ri
R
Qiu
Hong-Xia
HX
Shen
Yi-Min
YM
Zhang
Xu-Hui
XH
Xue
Sheng-Li
SL
Han
Yue
Y
D000328:Adult; D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D003606:Dacarbazine / Q000008:administration & dosage; D054739:Dendritic Cell Sarcoma, Interdigitating / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism*; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009418:S100 Proteins / Q000032:analysis; D016896:Treatment Outcome; D014747:Vinblastine / Q000008:administration & dosage; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D001761:Bleomycin; D003606:Dacarbazine; D004317:Doxorubicin; D009418:S100 Proteins; D014747:Vinblastine; C067980:CD68 antigen, human; D000097382:CD68 Molecule