[The changes of bacteria group on oral mucosa after radiotherapy of postoperative patients of oral carcinoma].
OBJECTIVE
To investigate the microbial contents presented on the surface of mucosa in the oral cavity of patients who accepted radiotherapy, and to provide the evidences of controlling post-radiotherapeutic infections.


METHODS
32 patients (19 males and 13 females) aged from 37 - 72 received radiotherapy after oral squamous cell carcinomas operation were selected. Samples of saliva were obtained from the radiated center and opposite mucosa before and after radiotherapy. The detective amount, detective ratio and constituent ratio were analysed by cultivation and identification.


RESULTS
Streptococci, Candida albicans and Pseudomonas aeruginosa significantly increased on both sides of the oral mucosa while Neisseria and Actinobacillus decreased on radiated region after the radiotherapy.


CONCLUSIONS
Radiotherapy has great effects on oral bacteria and pathogenic organism may play a role in post-radiotherapy infections. It is necessary to do bacteria culture and choose sensitive antibiotics regularly for post-radiotherapeutic patients.
Liu
Kun
K
Dept. of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, Chengdu 610041, China.
Gao
Ning
N
Wang
Yi-Chuan
YC
Wang
Chang-Mei
CM
Wang
Xiao-Yi
XY
Gao
Qing-Hong
QH
Xuan
Ming
M
Wen
Yu-Ming
YM
D000900:Anti-Bacterial Agents; D001419:Bacteria / Q000302:isolation & purification*; D002176:Candida albicans / Q000302:isolation & purification; D002294:Carcinoma, Squamous Cell / Q000382:microbiology / Q000532:radiotherapy*; D006801:Humans; D009061:Mouth Mucosa / Q000382:microbiology*; D009062:Mouth Neoplasms / Q000382:microbiology / Q000532:radiotherapy*; D011184:Postoperative Period; D012463:Saliva
D000900:Anti-Bacterial Agents