title: A case of Cronkhite-Canada syndrome with taste disturbance as a leading complaint.
abstract: Cronkhite-Canada syndrome was first described in 1955. The clinical features of this rare syndrome of unknown etiology include nonhereditary gastrointestinal polyposis together with diarrhea, nail dystrophy, alopecia, and hyperpigmentation of the skin. This syndrome has been divided into five clinical types based on initial symptoms. We describe a case of Cronkhite-Canada syndrome presenting with taste disturbance as the major symptom, present a comprehensive review of the literature concerning this rare syndrome, and suggest therapeutic treatment options.
authors.affiliation: Division of Gastroenterology, University of Pennsylvania Health System, Philadelphia, Pa. 19104, USA.
authors.forename: Wojciech C
authors.initials: WC
authors.lastname: Blonski
authors.forename: Emma E
authors.initials: EE
authors.lastname: Furth
authors.forename: Bruce P
authors.initials: BP
authors.lastname: Kinosian
authors.forename: Charlene
authors.initials: C
authors.lastname: Compher
authors.forename: David C
authors.initials: DC
authors.lastname: Metz
mesh_terms: D003937:Diagnosis, Differential; D004408:Dysgeusia / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D044483:Intestinal Polyposis / Q000175:diagnosis*; D015032:Zinc / Q000172:deficiency / Q000627:therapeutic use
chemical_list: D015032:Zinc