Gastrointestinal and hepatobiliary manifestations in systemic lupus erythematosus.
OBJECTIVE
To report GI and Hepatobiliary manifestations in SLE from Chulalongkorn Hospital in the year 2000.


METHODS
A retrospective study of SLE patients in the Rheumatological Clinic, Medical Department, Chulalongkorn University.


RESULTS
A total 225 SLE patients were found being mainly female (93.3%). The mean age was 32.13 +/- 11.65 years and they almost all lived in the central part of Thailand (79.1%). At diagnosis, the majority of SLE cases are active vital organ (72.1%), kidney and central nervous system are the main organ of involvement. GI and hepatobiliary manifestations were found in 32.89% but did not lead to SLE diagnosis. The duration between SLE diagnosis and first GI and hepatobiliary manifestations is 4.6 +/- 4.4 years. The 3 common manifestations are abnormal liver function test, diarrhea and abdominal pain, with the prevalance rate of 34, 17 and 11% respectively.


CONCLUSIONS
GI and hepatobiliary manifestations of SLE patients in Chulalongkorn Hospital were found in 32.89% but were not specific and could be found in any part of the alimentary tract. The 3 common manifestations were abnormal liver function tests, diarrhea and abdominal pain which were not specific enough to diagnose SLE.
Luangjaru
Somchai
S
Department of Medicine, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima 30000, Thailoand.
Kullavanijaya
Pinit
P
D000293:Adolescent; D000328:Adult; D004066:Digestive System Diseases / Q000209:etiology*; D005260:Female; D006785:Hospitals, University; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013785:Thailand