title: [Diagnosis and therapy of Parkinson's disease].
abstract: The clinical diagnosis of Parkinson's disease is mainly based upon the principal symptoms bradykinesia, rigidity and tremor at rest. The differential diagnosis of idiopathic Parkinson's disease (IPD) from other parkinsonisms is from the prognostic and therapeutic standpoint of considerable importance because the Parkinson-Plus syndrome generally does not or only poorly responds to a dopaminergic therapy. The treatment of IPD comprises, in addition to, dopaminergic medications such as L-dopa or dopamine receptor agonists, operative therapeutic options such as deep brain stimulation and nondrug therapies.
authors.affiliation: Klinik und Poliklinik für Neurologie, Universität Rostock. matthias.wittstock@med.uni-rostock.de
authors.forename: M
authors.initials: M
authors.lastname: Wittstock
authors.forename: R
authors.initials: R
authors.lastname: Benecke
mesh_terms: D000978:Antiparkinson Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D015259:Dopamine Agents / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007980:Levodopa / Q000009:adverse effects / Q000627:therapeutic use; D009460:Neurologic Examination; D010300:Parkinson Disease / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D000978:Antiparkinson Agents; D015259:Dopamine Agents; D007980:Levodopa