Paracetamol poisoning: physiological aspects and management strategies.
This article identifies the physiological aspects of paracetamol poisoning, as well as appropriate treatments. Trends in paracetamol use and initiatives to reduce rates of self-harm are discussed, as well as clinical practice and ways to determine severity of poisoning.
Farley
Alistair
A
Ninewells Hospital, Dundee. a.h.farley@dundee.ac.uk
Hendry
Charles
C
Napier
Pamela
P
D000082:Acetaminophen / Q000378:metabolism / Q000506:poisoning* / Q000627:therapeutic use; D000111:Acetylcysteine / Q000627:therapeutic use; D000328:Adult; D000367:Age Factors; D018712:Analgesics, Non-Narcotic / Q000378:metabolism / Q000506:poisoning* / Q000627:therapeutic use; D000931:Antidotes / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D016903:Drug Monitoring / Q000379:methods; D062787:Drug Overdose / Q000175:diagnosis / Q000453:epidemiology / Q000378:metabolism / Q000628:therapy; D016529:Emergency Nursing / Q000379:methods; D004638:Emergency Treatment / Q000379:methods* / Q000451:nursing; D005751:Gastric Lavage; D006801:Humans; D008657:Metabolic Clearance Rate; D008715:Methionine / Q000627:therapeutic use; D009730:Nursing Assessment; D011379:Prognosis; D016728:Self-Injurious Behavior / Q000175:diagnosis / Q000453:epidemiology / Q000378:metabolism / Q000628:therapy; D006113:United Kingdom / Q000453:epidemiology
D018712:Analgesics, Non-Narcotic; D000931:Antidotes; D000082:Acetaminophen; D008715:Methionine; D000111:Acetylcysteine