title: Quinolone-resistant uropathogenic Escherichia coli strains from phylogenetic group B2 have fewer virulence factors than their susceptible counterparts.
abstract: The prevalence of 31 virulence factors was analyzed among nalidixic acid-susceptible and -resistant Escherichia coli strains from phylogenetic group B2. Hemolysin, cytotoxic necrotizing factor 1, and S and F1C fimbriae genes were less prevalent among nalidixic acid-resistant E. coli strains. Quinolone resistance may be associated with a decrease in the presence of some virulence factors.
authors.affiliation: Service of Infectious Diseases, Hospital Clínic Universitari-IDIBAPS, Villaroel 170, 08036 Barcelona, Spain. jhorcaja@yahoo.es
authors.forename: Juan P
authors.initials: JP
authors.lastname: Horcajada
authors.forename: Sara
authors.initials: S
authors.lastname: Soto
authors.forename: Abby
authors.initials: A
authors.lastname: Gajewski
authors.forename: Alex
authors.initials: A
authors.lastname: Smithson
authors.forename: M Teresa
authors.initials: MT
authors.lastname: Jiménez de Anta
authors.forename: Josep
authors.initials: J
authors.lastname: Mensa
authors.forename: Jordi
authors.initials: J
authors.lastname: Vila
authors.forename: James R
authors.initials: JR
authors.lastname: Johnson
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000472:pathogenicity; D004927:Escherichia coli Infections / Q000382:microbiology; D029968:Escherichia coli Proteins / Q000235:genetics / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D009268:Nalidixic Acid / Q000494:pharmacology; D010802:Phylogeny; D015363:Quinolones / Q000494:pharmacology*; D014570:Urologic Diseases / Q000382:microbiology*; D014774:Virulence; D037521:Virulence Factors / Q000235:genetics* / Q000378:metabolism
chemical_list: D000890:Anti-Infective Agents; D029968:Escherichia coli Proteins; D015363:Quinolones; D037521:Virulence Factors; D009268:Nalidixic Acid