Erythromycin-nonsusceptible Streptococcus pneumoniae in children, 1999-2001.
After increasing from 1995 to 1999, invasive erythromycin-nonsusceptible Streptococcus pneumoniae rates per 100,000 decreased 53.6% in children from Baltimore, Maryland (US), from 1999 to 2001, which was partially attributed to strains related to the mefE-carrying England14-9 clone. The decline in infection rates was likely due to the pneumococcal 7-valent conjugate vaccine.
McEllistrem
M Catherine
MC
University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania 15213-2582, USA. mcellistremc@msx.dept-med.pitt.edu
Adams
Jennifer M
JM
Shutt
Kathleen
K
Sanza
Laurie T
LT
Facklam
Richard R
RR
Whitney
Cynthia G
CG
Jorgensen
James H
JH
Harrison
Lee H
LH
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004917:Erythromycin / Q000494:pharmacology*; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008396:Maryland / Q000453:epidemiology; D008565:Membrane Proteins / Q000235:genetics; D008826:Microbial Sensitivity Tests; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013296:Streptococcus pneumoniae / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; C431304:MefE protein, Streptococcus pneumoniae; D008565:Membrane Proteins; D004917:Erythromycin