T-cell clonality of peripheral blood lymphocytes in patients with lymphomatoid papulosis.
Six patients with lymphomatoid papulosis demonstrated a clonal T-cell population in skin lesions by polymerase chain reaction methods. Two of these patients showed identical T-cell clones in their peripheral blood T cells as well. In one case, the clone persisted in the blood despite clearing of skin lesions with methotrexate.
Schultz
Julie C
JC
Dermatology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.
Granados
Suzanne
S
Vonderheid
Eric C
EC
Hwang
Sam T
ST
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D017731:Lymphomatoid Papulosis / Q000097:blood* / Q000276:immunology*; D008875:Middle Aged; D013601:T-Lymphocytes