title: Complete resection in lung cancer surgery: proposed definition.
abstract: OBJECTIVE
  To propose an internationally accepted definition of complete resection in lung cancer surgery.
  
  
  METHODS
  The International Association for the Study of Lung Cancer (IASLC) Staging Committee created the Complete Resection Subcommittee in 2001 to work on an international definition of complete resection in lung cancer surgery. The previous definitions of complete resection and the rules of the International Union Against Cancer regarding the TNM residual tumor classification, together with a thorough review of the pertinent literature, and the input of the members of the IASLC Staging Committee were considered in order to get an international consensus on the definition of complete resection in lung cancer surgery.
  
  
  RESULTS
  Complete resection requires all of the following: free resection margins proved microscopically; systematic nodal dissection or lobe-specific systematic nodal dissection; no extracapsular nodal extension of the tumor; and the highest mediastinal node removed must be negative. Whenever there is involvement of resection margins, extracapsular nodal extension, unremoved positive lymph nodes or positive pleural or pericardial effusions, the resection is defined as incomplete. When the resection margins are free and no residual tumor is left, but the resection does not fulfill the criteria for complete resection, there is carcinoma in situ at the bronchial margin or positive pleural lavage cytology, the term uncertain resection is proposed.
  
  
  CONCLUSIONS
  The proposed definitions of complete, incomplete and uncertain resections are clear and reproducible in an international setting to study their prognostic impact prospectively.
authors.affiliation: Complete Resection Subcommittee of the IASLC Staging Committee, Thoracic Surgery Service, Hospital Mutua de Terrassa, University of Barcelona, Plaza Dr. Robert, 5, 08221 Terrassa, Barcelona, Spain. rramip@teleline.es
authors.forename: Ramón
authors.initials: R
authors.lastname: Rami-Porta
authors.forename: Christian
authors.initials: C
authors.lastname: Wittekind
authors.forename: Peter
authors.initials: P
authors.lastname: Goldstraw
mesh_terms: D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000601:surgery*; D008197:Lymph Node Excision; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011013:Pneumonectomy; D011379:Prognosis; D009626:Terminology as Topic