title: 32P brachytherapy in the treatment of complex Cypher in-stent restenosis.
abstract: Treatment of in-stent restenosis after implantation of a drug-eluting stent is a critical issue. We provide the first report of the use of intravascular radiation therapy for this purpose in a 73-year-old diabetic patient stented for small-vessel bifurcation; treatment of Cypher diffuse in-stent restenosis with (32)P brachytherapy proved successful at clinical and angiographic follow-up at 7 months. This finding should encourage systematic studies on the safety and efficacy of IRT in this problematic setting.
authors.affiliation: Institute of Cardiology, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy. paortal@tin.it
authors.forename: Paolo
authors.initials: P
authors.lastname: Ortolani
authors.forename: Antonio
authors.initials: A
authors.lastname: Marzocchi
authors.forename: Matteo
authors.initials: M
authors.lastname: Aquilina
authors.forename: William
authors.initials: W
authors.lastname: Gaiba
authors.forename: Stefano
authors.initials: S
authors.lastname: Neri
authors.forename: Cinzia
authors.initials: C
authors.lastname: Marrozzini
authors.forename: Tullio
authors.initials: T
authors.lastname: Palmerini
authors.forename: Nevio
authors.initials: N
authors.lastname: Taglieri
authors.forename: A
authors.initials: A
authors.lastname: Branzi
mesh_terms: D000368:Aged; D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation; D001918:Brachytherapy / Q000379:methods*; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D003331:Coronary Vessels / Q000528:radiation effects / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000601:surgery; D010761:Phosphorus Radioisotopes / Q000627:therapeutic use; D011475:Prosthesis Failure; D015607:Stents
chemical_list: D010761:Phosphorus Radioisotopes