Cronkhite-Canada syndrome with hypothyroidism.
Cronkhite-Canada syndrome is a rare, noninherited gastrointestinal polyposis syndrome associated with characteristic ectodermal abnormalities. This report describes a 60-year-old female who was diagnosed with Cronkhite-Canada syndrome with hypothyroidism after presenting with chronic diarrhea, alopecia, intermittent abdominal pain, generalized gastrointestinal polyposis, hyperpigmentation, and nail dystrophy. Endoscopic examination of the stomach and duodenum showed multiple sessile polyps and mucosal erosion associated with evidence of chronic inflammation. Colonoscopy also revealed mucosal edema and diffuse polyposis.
Qiao
Mei
M
Digestive Department, The First Affiliated Hospital of Anhui Medical University, Heifei, China. meiqiao@hotmail.com
Lei
Zhang
Z
Nai-Zhong
Hu
H
Jian-Ming
Xu
X
D003113:Colonoscopy; D005260:Female; D006801:Humans; D007037:Hypothyroidism; D044483:Intestinal Polyposis / Q000473:pathology; D008875:Middle Aged