Prevalence of premature urinary luteinizing hormone surges in women with regular menstrual cycles and its effect on implantation of frozen-thawed embryos.
OBJECTIVE
To determine the frequency and effect of premature luteinizing hormone (LH) surges on pregnancy rates in women with regular menstrual cycles.


METHODS
Retrospective cohort study.


METHODS
Assisted Reproductive Technology Program at private medical college.


METHODS
Regularly menstruating women undergoing frozen embryo transfer (ET).


METHODS
Detection of urinary LH surges with an RIA kit during natural-cycle frozen-embryos transfer.


METHODS
Incidence of premature LH surges and pregnancy outcomes.


RESULTS
Eighty-eight (46.8%) of 188 regularly menstruating women had premature LH surges and 33 (37%) of those 88 had multiple premature LH surges. Pregnancy rates per ET are similar between women with and without premature LH surges.


CONCLUSIONS
A high percentage of normally cycling women demonstrate premature urinary LH surges without an effect on outcome of frozen-thawed ETs.
Krotz
Stephan
S
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA.
McKenzie
Laurie J
LJ
Cisneros
Pauline
P
Buster
John
J
Amato
Paula
P
Carson
Sandra
S
D000328:Adult; D016009:Chi-Square Distribution; D015331:Cohort Studies; D015925:Cryopreservation / Q000706:statistics & numerical data*; D010064:Embryo Implantation / Q000502:physiology*; D005260:Female; D006801:Humans; D007986:Luteinizing Hormone / Q000652:urine*; D008597:Menstrual Cycle / Q000652:urine*; D008875:Middle Aged; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology; D015995:Prevalence; D012189:Retrospective Studies; D018709:Statistics, Nonparametric
D007986:Luteinizing Hormone