title: Addressing the global cardiovascular risk of hypertension, dyslipidemia, and insulin resistance in the southeastern United States.
abstract: An expanded occurrence of the metabolic syndrome in the U.S. population, especially in the Southeastern United States, has raised awareness of a need to revise our approach to the management of global cardiovascular risk factors while underscoring a need for more aggressive interventions and prevention measures. In defining the components of the metabolic syndrome and the interrelationship among obesity, hypertension, dyslipidemia, and insulin resistance, a basic framework for the medical management of this syndrome has been defined. In Part I of the consensus report prepared by the Workgroup on Medical Guidelines of the Consortium for Southeastern Hypertension Control (COSEHC), we analyze the components of the metabolic syndrome, discuss its pathophysiology, and recommend an approach to the quantitative analysis of the risk factors contributing to excess cardiovascular death in the region.
authors.affiliation: Consortium for Southeastern Hypertension Control (COSEHC) and Vanderbilt University School of Medicine and St. Thomas Hospital, Nashville, Tennessee, USA.
authors.forename: Mark C
authors.initials: MC
authors.lastname: Houston
authors.forename: Jan
authors.initials: J
authors.lastname: Basile
authors.forename: William H
authors.initials: WH
authors.lastname: Bestermann
authors.forename: Brent
authors.initials: B
authors.lastname: Egan
authors.forename: Daniel
authors.initials: D
authors.lastname: Lackland
authors.forename: Ralph G
authors.initials: RG
authors.lastname: Hawkins
authors.forename: Michael A
authors.initials: MA
authors.lastname: Moore
authors.forename: James
authors.initials: J
authors.lastname: Reed
authors.forename: Philip
authors.initials: P
authors.lastname: Rogers
authors.forename: Daniel
authors.initials: D
authors.lastname: Wise
authors.forename: Carlos M
authors.initials: CM
authors.lastname: Ferrario
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000209:etiology*; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications*; D006973:Hypertension / Q000150:complications* / Q000453:epidemiology; D024821:Metabolic Syndrome / Q000150:complications*; D008875:Middle Aged; D012307:Risk Factors; D012737:Sex Factors; D015144:Southeastern United States / Q000453:epidemiology