title: Management of facial dysmorphogenesis in nemaline myopathy: a case report.
abstract: Nemaline myopathy is a rare congenital muscle disease, which is clinically and genetically heterogeneous. Both neonatal and adult onset can occur; in those with neonatal onset, the resulting muscle weakness can also afflict the facial musculature and hence influence facial growth and development. This article reports on a case in which no orthodontic intervention was undertaken during childhood and adolescence. An early decision was made to treat the facial dysmorphogenesis surgically once skeletal maturity had been reached. The authors discuss and illustrate the untreated facial growth in this condition and the surgical outcome following orthodontic treatment and orthognathic surgery.
authors.affiliation: Australian Craniofacial Unit, Women's and Children's Hospital, 72 King William Street, North Adelaide, South Australia SA5006, Australia. haemro2@hotmail.com
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Anderson
authors.forename: John H
authors.initials: JH
authors.lastname: Barker
authors.forename: David J
authors.initials: DJ
authors.lastname: David
mesh_terms: D000293:Adolescent; D016025:Bone Transplantation; D019066:Facies; D005260:Female; D006801:Humans; D007569:Jaw Abnormalities / Q000209:etiology / Q000601:surgery*; D008310:Malocclusion / Q000209:etiology / Q000601:surgery / Q000628:therapy*; D017696:Myopathies, Nemaline / Q000150:complications*; D019647:Oral Surgical Procedures; D010155:Palatal Expansion Technique; D015050:Zygoma / Q000002:abnormalities / Q000601:surgery