Synthesis, characterisation and cytotoxicity of chloro derivatives of prenylnaphthohydroquinone.
From the Diels-Alder adduct between alpha-myrcene and 2-chloro-1,4-benzoquinone, a family of chloro derivatives of prenylnaphthohydroquinone have been synthesised and evaluated for their cytotoxicity against 14 neoplastic cell lines.
Molinari
Aurora
A
Instituto de Química, Pontificia Universidad Católica de Valparaíso, Casilla 4059 Valparaíso, Chile. amolinar@ucv.cl
Oliva
Alfonso
A
Ojeda
Claudia
C
Escobar
Jorge
J
Gallardo
Carolina
C
Miguel del Corral
José Ma
JM
Castro
Ma Angeles
MA
Cuevas
Carmen
C
San Feliciano
Arturo
A
D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D006873:Hydroquinones / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D019169:Jurkat Cells; D009682:Magnetic Resonance Spectroscopy; D013055:Spectrophotometry, Infrared
D000970:Antineoplastic Agents; D006873:Hydroquinones; C493261:prenylnaphthohydroquinone