Basal ganglia calcification and psychosis in 22q11.2 deletion syndrome.
Intracerebral calcifications are a facultative symptom of hypoparathyreoidism in 22q11.2 deletion syndrome (22qDS). We describe a patient with 22qDS, basal ganglia calcification (BGC) and psychotic symptoms and discuss the etiological connection of BGC with psychiatric symptoms. Future work needs to determine the prevalence of BGC in 22qDS and psychiatric disorders.
Sieberer
M
M
Department of Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany. Sieberer.Marcel@mh-hannover.de
Haltenhof
H
H
Haubitz
B
B
Pabst
B
B
Miller
K
K
Garlipp
P
P
D000328:Adult; D001480:Basal Ganglia Diseases / Q000150:complications / Q000235:genetics / Q000473:pathology; D002114:Calcinosis / Q000150:complications / Q000235:genetics / Q000473:pathology; D002872:Chromosome Deletion; D002892:Chromosomes, Human, Pair 22 / Q000235:genetics*; D004062:DiGeorge Syndrome / Q000150:complications / Q000235:genetics / Q000473:pathology; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D015995:Prevalence; D011618:Psychotic Disorders / Q000150:complications / Q000235:genetics / Q000473:pathology; D012559:Schizophrenia / Q000150:complications / Q000235:genetics / Q000473:pathology