Pigmented purpuric dermatosis and hepatitis profile: a report on 10 patients.
BACKGROUND
Pigmented purpuric dermatosis comprises a group of vascular disorders of unknown etiology. Histologically, it is characterized by lymphocytic capillaritis in the papillary dermis. Although leukocytoclastic vasculitis confined to the skin is frequently reported with hepatitis C, lymphocytic vasculitis is rarely reported.


METHODS
Ten patients with pigmented purpuric dermatosis were studied clinically and histopathologically. Hepatitis profile was carried out in all of the patients to evaluate the possible relation.


RESULTS
Of the 10 patients, five tested positive for hepatitis C and two for hepatitis B antibodies.


CONCLUSIONS
Hepatitis C and B virus may play a role in the pathogenesis of pigmented purpuric dermatosis. Further case-control studies are necessary to confirm this conclusion.
Dessoukey
M Wagdy
MW
Department of Dermatology, Al-Jazeera Hospital, Abu Dhabi, United Arab Emirates. dessouky@emirates.net.ae
Abdel-Dayem
Hussein
H
Omar
Mohamed F
MF
Al-Suweidi
Naeema E
NE
D000328:Adult; D000368:Aged; D005260:Female; D006510:Hepatitis B Antibodies / Q000097:blood*; D018937:Hepatitis C Antibodies / Q000097:blood*; D006801:Humans; D007868:Leg Dermatoses / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D010859:Pigmentation Disorders / Q000276:immunology*; D011693:Purpura / Q000276:immunology*
D006510:Hepatitis B Antibodies; D018937:Hepatitis C Antibodies