Detrimental effects of immobilization on functional recovery after sciatic nerve crush.
Peripheral-nerve trauma has been a challenge to surgeons, with significant advances in the surgery of repair. Immobilization of the injured limb after repair has been the traditional method of treatment. Although peripheral-nerve regeneration has been studied extensively, the correlation between functional recovery and the immobilization period has not been well-documented. In the present study, the authors studied the effects of immobilization on axonal regeneration after sciatic crush injury. They found a detrimental effect of immobilization on the functional recovery.
Sarikcioglu
Levent
L
Department of Anatomy, Akdeniz University Faculty of Medicine, 07070 Antalya, Turkey.
Ozkan
Olcay
O
Gurer
Elif Inanc
EI
D000818:Animals; D001369:Axons / Q000502:physiology*; D005260:Female; D009416:Nerve Regeneration; D051381:Rats; D017208:Rats, Wistar; D020127:Recovery of Function; D012149:Restraint, Physical / Q000009:adverse effects*; D012584:Sciatic Nerve / Q000293:injuries*; D013997:Time Factors