title: Calcitonin gene-related peptide during sweating in young healthy women.
abstract: Calcitonin gene-related peptide (CGRP) concentrations are increased in postmenopausal women and castrated men with symptomatic flushing. We wanted to determine if a CGRP increase exists in the plasma of healthy fertile-age women during sweating. Plasma concentrations of CGRP were measured by radioimmunoassay at maximal sweating during a sauna session and during bicycle exercise both at maximal and 70% of maximal work capacity in 8 healthy women of fertile age. Plasma concentrations of CGRP were unaffected (>90% statistical power) during both experimental sessions. We suggest that sweating itself does not explain the rise in CGRP concentrations observed in flushing postmenopausal women.
authors.affiliation: Division of Obstetrics and Gynecology, Faculty of Health Sciences, University Hospital, Linkoping, Sweden. Anna-Clara.Spetz@LiO.se
authors.forename: Anna-Clara E
authors.initials: AC
authors.lastname: Spetz
authors.forename: Katrine
authors.initials: K
authors.lastname: Ellefsen
authors.forename: Elvar
authors.initials: E
authors.lastname: Theodorsson
authors.forename: Claes T
authors.initials: CT
authors.lastname: Lassvik
authors.forename: Mats L
authors.initials: ML
authors.lastname: Hammar
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001831:Body Temperature; D015740:Calcitonin Gene-Related Peptide / Q000097:blood*; D015444:Exercise; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D010060:Ovulation; D011388:Prolactin / Q000097:blood; D012016:Reference Values; D013546:Sweating / Q000502:physiology
chemical_list: D015415:Biomarkers; D011388:Prolactin; D015740:Calcitonin Gene-Related Peptide; D006854:Hydrocortisone