title: The effect of magnesium sulfate treatment on serum cardiac troponin I levels in preeclamptic women.
abstract: OBJECTIVE
  To investigate serum cardiac troponin I levels before and after magnesium sulfate treatment in preeclamptic pregnant women.
  
  
  METHODS
  Fifty-five pregnant women were included in the prospectively planned study. Study group patients (n = 25) were pregnant women hospitalized with a preeclampsia diagnosis while the control group (n = 30) were pregnant women with no medical or obstetric problem who had been attending the antenatal clinic. Serum cardiac troponin I levels were compared in the normal pregnant women and in preeclamptic pregnant women. These levels were also compared in the preeclamptic women before and after magnesium sulfate treatment. Mann-Whitney U-test was used for statistical analysis.
  
  
  RESULTS
  Groups were similar with respect to age, gravity, parity, and gestational age. The median serum cardiac troponin I levels in preeclamptic patients was 0.20 ng/ml (0.02-4.53) before treatment and 0.09 ng/ml (0.02-3.91) after treatment, while it was 0.02 ng/ml (0.0-0.05) in the control group. The serum cardiac troponin I level in the preeclamptic group was significantly high (P < 0.01), and pretreatment values in this group were significantly higher compared with post-treatment values (P < 0.01)
  
  
  CONCLUSIONS
  Cardiac troponin I is a sensitive parameter for indicating minor myocardial damage which may occur in preeclampsia and for evaluating the efficiency of magnesium sulfate treatment.
authors.affiliation: Gynecology and Obstetric Department of Ankara Numune Education and Research Hospital, Ankara, Turkey. cfatalay@superonline.com
authors.forename: Cemal
authors.initials: C
authors.lastname: Atalay
authors.forename: Gönül
authors.initials: G
authors.lastname: Erden
authors.forename: Turan
authors.initials: T
authors.lastname: Turhan
authors.forename: Gülbin
authors.initials: G
authors.lastname: Yildiran
authors.forename: O Ferit
authors.initials: OF
authors.lastname: Saraçoglu
authors.forename: Yüksel
authors.initials: Y
authors.lastname: Koca
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008278:Magnesium Sulfate / Q000627:therapeutic use*; D011225:Pre-Eclampsia / Q000097:blood* / Q000188:drug therapy*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood*; D011446:Prospective Studies; D018709:Statistics, Nonparametric; D015149:Tocolytic Agents / Q000627:therapeutic use*; D019210:Troponin I / Q000097:blood*
chemical_list: D015149:Tocolytic Agents; D019210:Troponin I; D008278:Magnesium Sulfate