General mathematical frame for open or closed biomembranes (Part I): equilibrium theory and geometrically constraint equation.
This paper aims at constructing a general mathematical frame for the equilibrium theory of open or closed biomembranes. Based on the generalized potential functional, the equilibrium differential equation for open biomembrane (with free edge) or closed one (without boundary) is derived. The boundary conditions for open biomembranes are obtained. Besides, the geometrically constraint equation for the existence, formation and disintegration of open or closed biomembranes is revealed. The physical and biological meanings of the equilibrium differential equation and the geometrically constraint equation are discussed. Numerical simulation results for axisymmetric open biomembranes show the effectiveness and convenience of the present theory.
Yin
Yajun
Y
Department of Engineering Mechanics, School of Aerospace, FML Tsinghua University, 100084 Beijing, China. yinyj@mail.tsinghua.edu.cn
Yin
Jie
J
Ni
Dong
D
D001696:Biomechanical Phenomena; D048430:Cell Shape / Q000502:physiology; D004912:Erythrocytes / Q000166:cytology / Q000502:physiology; D006801:Humans; D066298:In Vitro Techniques; D008433:Mathematics; D008566:Membranes / Q000502:physiology*; D008954:Models, Biological; D011312:Pressure; D013816:Thermodynamics