title: Practical synthesis of (Z)-polyaromatic and heteroaromatic vinylacetylenes.
abstract: [reaction: seet text] Two synthetic routes to several (Z)-polyaromatic and heteroaromatic substituted vinylacetylenes are described. The nature of aryl- or heteroaryl-substituted carboxaldehyde used as starting material dictated the choice of Wittig salt employed. A very attractive way to construct polyaromatic and pyridine-containing enynes is the reaction of polyaromatic and pyridine-containing aldehydes with bromomethyltriphenylphosphonium bromide in the presence of potassium tert-butoxide followed by a Sonogashira desilylation procedure (method B).
authors.affiliation: Department of Chemistry, Thomas Harriot College of Arts and Sciences, East Carolina University, Science and Technology Building, Suite 300, Greenville, North Carolina 27858-4343, USA. hayforda@mail.ecu.edu
authors.forename: Anthony
authors.initials: A
authors.lastname: Hayford
authors.forename: Joseph
authors.initials: J
authors.lastname: Kaloko
authors.forename: Salwa
authors.initials: S
authors.lastname: El-Kazaz
authors.forename: Gwen
authors.initials: G
authors.lastname: Bass
authors.forename: Cheryl
authors.initials: C
authors.lastname: Harrison
authors.forename: Thomas
authors.initials: T
authors.lastname: Corprew