[Measurement of peak inspiratory flow with asthma: effect of inhaled beta2-stimulant].
This study was designed to evaluate peak inspiratory flow (PIF) and peak expiratory flow (PEF) in 24 patients with mild asthma. After inhalation of a beta2-stimulant (beta2), PIF significantly increased from 173.0 +/- 67.0 (range 70-300 L/min) to 194.0 +/- 66.7 after 1 minute, and to 199.3 +/- 63.0 after 15 minutes (p < 0.0025, and p < 0.008, respectively). PEF also significantly increased. The previous inhalation of beta2 improved the efficacy of inhalation of dry powder. This evidence should be considered in performing patient education for effective methods of inhalation.
Shimizu
Keiko
K
Takamatsu Municipal Hospital Division of Pharmacy.
Yamazaki
Yasuhiro
Y
Kishimoto
Nobuhito
N
Tada
Shinya
S
Ueda
Nobuo
N
Fujita
Jiro
J
Kamei
Tadashi
T
Okada
Hiroki
H
Arakawa
Yuko
Y
Nakamura
Hiroyuki
H
D000280:Administration, Inhalation; D000318:Adrenergic beta-Agonists / Q000008:administration & dosage* / Q000627:therapeutic use; D000328:Adult; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009330:Nebulizers and Vaporizers; D010366:Peak Expiratory Flow Rate / Q000187:drug effects*
D000318:Adrenergic beta-Agonists; D018927:Anti-Asthmatic Agents