Fluorescence probes for thiol-containing amino acids and peptides in aqueous solution.
A new fluorescence probe is described using the "chemosensing ensemble" method. The probe shows high selectivity and sensitivity for thiol-containing amino acids and peptides, and can detect cysteine and homocysteine from healthy to abnormal levels under physiologically-relevant conditions.
Fu
Yanyan
Y
Organic Solid Laboratory, Institute of Chemistry, Chinese Academy of Sciences, Beijing.
Li
Hongxiang
H
Hu
Wenping
W
Zhu
Daoben
D
D000596:Amino Acids / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry*; D012996:Solutions; D013050:Spectrometry, Fluorescence; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D014867:Water
D000596:Amino Acids; D005456:Fluorescent Dyes; D010455:Peptides; D012996:Solutions; D013438:Sulfhydryl Compounds; D014867:Water