Successful pregnancy of a patient with Balo's concentric sclerosis.
Balo's concentric sclerosis is a severe demyelinating disease with poor prognosis. To date, nothing is known about the effects of pregnancy on the course of Balo's disease. We describe here the first successful pregnancy of a patient with Balo's concentric sclerosis. Upon neurological worsenings during pregnancy, our patient was treated with high-dose methylprednisolone and plasma-exchange. Intravenous immunoglobulin and interferon-beta-1a were given postpartum. At the last follow-up visit 2.5 years after the delivery the patient had only minor residual symptoms.
Airas
Laura
L
Department of Neurology, Turku University Hospital, Turku, Finland. laura.airas@utu.fi
Kurki
Timo
T
Erjanti
Hanna
H
Marttila
Reijo J
RJ
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000188:drug therapy* / Q000473:pathology*; D005260:Female; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage*; D010951:Plasma Exchange; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome
D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone