title: Extraventricular neurocytoma presenting with intratumoral hemorrhage.
abstract: A case of extraventricular neurocytoma with spontaneous intratumoral hemorrhage is reported. A 47-year-old man presented with sudden left-sided hemiparesis. Magnetic resonance imaging revealed a right parietal subcortical mass with intratumoral hemorrhagic transformation and without contact to the ventricular system. After complete microsurgical removal, the tumor was histologically diagnosed as neurocytoma. Usually, the term "central neurocytoma" is restricted to neurocytic neoplasms arising within the cerebral ventricles. In the majority of the cases, these slow-growing, generally circumscribed lesions become symptomatic by obstructive hydrocephalus. Hemorrhagic onset is sporadically reported in the literature. In contrast to central neurocytomas, neurocytic lesions located within the brain parenchyma, so-called "extraventricular neurocytomas" are very uncommon. To the knowledge of the authors, this is the first case of an extraventricular neurocytoma with histological classic features presenting with intratumoral hemorrhage in adults.
authors.affiliation: Department of Neurosurgery, University Hospital, Eberhard, Germany. rainer.ritz@med.uni-tuebingen.de
authors.forename: R
authors.initials: R
authors.lastname: Ritz
authors.forename: F
authors.initials: F
authors.lastname: Roser
authors.forename: A
authors.initials: A
authors.lastname: Bornemann
authors.forename: U
authors.initials: U
authors.lastname: Hahn
authors.forename: D
authors.initials: D
authors.lastname: Freudenstein
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism; D001929:Brain Edema / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D001932:Brain Neoplasms / Q000098:blood supply / Q000473:pathology* / Q000503:physiopathology; D002114:Calcinosis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D002543:Cerebral Hemorrhage / Q000209:etiology* / Q000473:pathology* / Q000503:physiopathology; D002552:Cerebral Ventricles / Q000473:pathology / Q000503:physiopathology; D006485:Hemosiderin / Q000378:metabolism; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000473:pathology; D018306:Neurocytoma / Q000098:blood supply / Q000473:pathology* / Q000503:physiopathology; D019635:Neurosurgical Procedures; D010291:Paresis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D016708:Synaptophysin / Q000378:metabolism; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; D016708:Synaptophysin; D006485:Hemosiderin