title: Sepsis and myocardial depression in a young woman.
abstract: Severe sepsis may be associated with depression of myocardial function, attributed to various inflammatory mediators. Myocardial dysfunction in sepsis is characterized by biventricular failure and complicates usual therapy with high-volume fluid resuscitation and vasopressors. However, in patients who survive septic shock, myocardial dysfunction can improve rapidly. We describe a young woman with septic shock due to Streptococcus pneumoniae, complicated by severe but reversible biventricular dysfunction.
authors.affiliation: Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
authors.forename: Mir Rauf
authors.initials: MR
authors.lastname: Subla
authors.forename: S Anjum
authors.initials: SA
authors.lastname: Khan
authors.forename: Deepti
authors.initials: D
authors.lastname: Behl
authors.forename: Steve G
authors.initials: SG
authors.lastname: Peters
mesh_terms: D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D003937:Diagnosis, Differential; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D011008:Pneumococcal Infections / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D013902:Radiography, Thoracic; D018805:Sepsis / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D013296:Streptococcus pneumoniae / Q000302:isolation & purification; D013318:Stroke Volume