title: Effects of acupuncture at GV01 on experimentally induced colitis in rats: possible involvement of the opioid system.
abstract: Oriental medicine uses acupuncture at the GV01 acupoint with great success to treat diarrhea. It significantly reduced the colonic motility and inflammation in colitic rats. Naloxone pretreatment blocked these effects. The therapeutic effects of acupuncture at GV01 in colitis may involve endogenous opioid pathways.
authors.affiliation: Department of Oriental Medical Science, Graduate School of East-West Medical Science, Kyung Hee University, Kyunggi-do 449-701, South Korea.
authors.forename: Hee-Young
authors.initials: HY
authors.lastname: Kim
authors.forename: Dae-Hyun
authors.initials: DH
authors.lastname: Hahm
authors.forename: Kwang-Ho
authors.initials: KH
authors.lastname: Pyun
authors.forename: Seung-Ki
authors.initials: SK
authors.lastname: Lee
authors.forename: Hye-Jung
authors.initials: HJ
authors.lastname: Lee
authors.forename: Tchi-Chou
authors.initials: TC
authors.lastname: Nam
authors.forename: Insop
authors.initials: I
authors.lastname: Shim
mesh_terms: D015669:Acupuncture Points; D015670:Acupuncture Therapy; D000818:Animals; D003092:Colitis / Q000139:chemically induced / Q000473:pathology / Q000628:therapy*; D003106:Colon / Q000187:drug effects / Q000201:enzymology / Q000473:pathology; D004195:Disease Models, Animal; D005769:Gastrointestinal Motility / Q000187:drug effects; D007279:Injections, Subcutaneous; D008297:Male; D009270:Naloxone / Q000008:administration & dosage / Q000494:pharmacology; D009292:Narcotic Antagonists / Q000008:administration & dosage / Q000494:pharmacology; D009195:Peroxidase / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D014302:Trinitrobenzenesulfonic Acid
chemical_list: D009292:Narcotic Antagonists; D009270:Naloxone; D014302:Trinitrobenzenesulfonic Acid; D009195:Peroxidase