title: Clear cell adenocarcinoma of the prostatic utricle in an adolescent.
abstract: We present a case of a 16-year-old boy with a primary clear cell adenocarcinoma of the prostatic utricle. The patient presented with a 6-month history of intermittent, nonpainful, gross hematuria and an associated right renal agenesis. Radiographic studies revealed the presence of a solid and cystic mass between the bladder neck and the cranium of the prostate. Serum tests, including prostate-specific antigen, carcinoembryonic antigen, CA-19-9, and human chorionic gonadotropin, were performed and found to be within normal limits. A surgical resection of the mass including prostate and seminal vesicles was performed. Grossly, a polypoid exophytic tumor was present at the prostatic utricle. Histologically, the tumor shows the classical clear cell morphology reminiscent of the so-called mesonephric adenocarcinomas. At clinical follow-up, the patient is alive and well 18 months after surgical resection. The present case highlights an unusual phenomenon of the development of an unusual form of adenocarcinoma in an adolescent.
authors.affiliation: Department of Pathology, Central Armed Forces Hospital, Montevideo, MDEO 11600, Uruguay. ggualco@adinet.com.uy
authors.forename: Gabriela
authors.initials: G
authors.lastname: Gualco
authors.forename: Virginia
authors.initials: V
authors.lastname: Ortega
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Ardao
authors.forename: Fernando
authors.initials: F
authors.lastname: Cravioto
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D000293:Adolescent; D014408:Biomarkers, Tumor / Q000378:metabolism; D018394:CA-125 Antigen / Q000378:metabolism; D006801:Humans; D007633:Keratins / Q000378:metabolism; D008297:Male; D011471:Prostatic Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor; D018394:CA-125 Antigen; D007633:Keratins