No adverse effects of adjuvant chemotherapy on hippocampal volume in Japanese breast cancer survivors.
We investigated the adverse effects of adjuvant chemotherapy on the hippocampus in Japanese breast cancer survivors with (n=44) and without (n=31) adjuvant chemotherapy. There were no significant differences in hippocampal volume (magnetic resonance imaging) or additionally in memory function (Wechsler Memory Scale-Revised) between the two groups.
Yoshikawa
Eisho
E
Psycho-Oncology Division, National Cancer Center Research Institute, 6-5-1 Kashiwanoha, Kashiwa 277-8577, Japan.
Matsuoka
Yutaka
Y
Inagaki
Masatoshi
M
Nakano
Tomohito
T
Akechi
Tatsuo
T
Kobayakawa
Makoto
M
Fujimori
Maiko
M
Nakaya
Naoki
N
Akizuki
Nobuya
N
Imoto
Shigeru
S
Murakami
Koji
K
Uchitomi
Yosuke
Y
D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000494:pharmacology* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000601:surgery; D005260:Female; D006624:Hippocampus / Q000187:drug effects*; D006801:Humans; D007564:Japan; D008279:Magnetic Resonance Imaging; D008408:Mastectomy; D008569:Memory Disorders / Q000139:chemically induced* / Q000175:diagnosis; D008875:Middle Aged; D009483:Neuropsychological Tests; D009929:Organ Size / Q000187:drug effects; D017741:Survivors
D000970:Antineoplastic Agents