Molecular evidence that nasal carriage of Staphylococcus aureus plays a role in respiratory tract infections of critically ill patients.
The relationship between nasal Staphylococcus aureus carriage and lower respiratory tract infections was studied in 16 critically ill patients. S. aureus strains from nasal and bronchial samples were characterized by pulsed-field gel electrophoresis. In all but one case, nasal and bronchial strains were genetically identical in the same patients.
Service de Réanimation, Médicale Assistance Respiratoire, Hôpital Gui de Chauliac, 80 avenue Augustin Fliche, 34295 Montpellier Cedex 5, France. p-corne@chu-montpellier.fr
Philippe
P
Corne
Hélène
H
Marchandin
Olivier
O
Jonquet
Josiane
J
Campos
Anne-Laure
AL
Bañuls
D000328:Adult; D000368:Aged; D001991:Bronchitis / Q000382:microbiology*; D002353:Carrier State / Q000382:microbiology*; D016638:Critical Illness; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009666:Nose / Q000382:microbiology*; D011023:Pneumonia, Staphylococcal / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000382:microbiology; D013211:Staphylococcus aureus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*