Palladium-catalyzed intramolecular selenocarbamoylation of alkynes with carbamoselenoates: formation of alpha-alkylidene-beta-lactam framework.
Pd-catalyzed intramolecular selenocarbamoylation of alkynes leading to alpha-alkylidene-beta-lactams was developed. This reaction can be applied to thiocarbamoylation and to the synthesis of delta- and epsilon-lactams and a cyclobutanone.
Department of Molecular Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Masashi
M
Toyofuku
Shin-ich
SI
Fujiwara
Tsutomu
T
Shin-ike
Hitoshi
H
Kuniyasu
Nobuaki
N
Kambe