Heterogeneity of genotype-phenotype correlation among macrolide-resistant Streptococcus agalactiae isolates.
Seventy-four erythromycin-resistant group B Streptococcus isolates were analyzed regarding their phenotype-genotype and phenotype-serotype correlation. Four different phenotypes were assessed, one of them for the first time. ermB and ermTR were the most frequent genotypes (80%). The most prevalent serotype III showed great phenotypic variability while serotype V was strongly associated only with two different phenotypes.
Department of Pediatrics and Adolescent Medicine, University Hospital of Freiburg, Mathildenstrasse 1, D-79106 Freiburg, Germany.
Ulrich
U
von Both
Anna
A
Buerckstuemmer
Kirsten
K
Fluegge
Reinhard
R
Berner
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004917:Erythromycin / Q000494:pharmacology*; D005838:Genotype; D006801:Humans; D018942:Macrolides / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests / Q000379:methods; D010641:Phenotype; D012703:Serotyping; D013292:Streptococcus agalactiae / Q000145:classification* / Q000187:drug effects* / Q000235:genetics
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D018942:Macrolides; D004917:Erythromycin