Solubilization of hydrophobic molecules in nanoparticles formed by polymer-surfactant interactions.
The interaction between the anionic surfactant, sodium dodecyl sulfate, and the polyelectrolyte, poly(diallyldimethylammonium chloride), may lead to formation of nanoparticles dispersed in water. The morphology of the resulting nanoparticles and their ability to solubilize hydrophobic molecules were evaluated. As shown by SEM and AFM imaging, the particles are spherical, having a diameter of about 20 nm. The solubilization within the nanoparticles was tested with pyrene, a fluorescence probe, and Nile Red, a solvatochromic probe. It was found that for Nile Red the solubilization within the nanoparticles is at lower polarity than for SDS micelles, and from pyrene solubilization it appears that the hydrophobicity of the nanoparticles depends on the ratio between the SDS molecules and the charge unit of the polymer.
Casali Institute of Applied Chemistry, Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Gilat
G
Nizri
Shlomo
S
Magdassi
D057927:Hydrophobic and Hydrophilic Interactions; D018625:Microscopy, Atomic Force; D008855:Microscopy, Electron, Scanning; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D010078:Oxazines / Q000737:chemistry; D010316:Particle Size; D011095:Polyethylenes / Q000737:chemistry*; D011721:Pyrenes / Q000737:chemistry; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D012967:Sodium Dodecyl Sulfate / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry
D010078:Oxazines; D011095:Polyethylenes; D011721:Pyrenes; D000644:Quaternary Ammonium Compounds; D013501:Surface-Active Agents; C041004:poly-N,N-dimethyl-N,N-diallylammonium chloride; D012967:Sodium Dodecyl Sulfate; C030984:pyrene; C044808:nile red