[Omission factors in detecting early stage prostate cancer by TRUS needle biopsy].
OBJECTIVE
To analyze and reduce the omission factors in detecting early stage prostate cancer by TRUS needle biopsy, and to improve the diagnosis of the disease.


METHODS
A total of 80 benign prostatic hyperplasia patients suspected of prostatic carcinoma underwent TRUS sextant biopsies. The pathological results being negative, the patients received transurethral resection of the prostate (TURP).


RESULTS
After TURP, 25 cases were pathologically diagnosed as prostate cancer, with an omission rate of 31.25% (25/80). Of the diagnosed cancer patients, 10 were treated by radical perineum prostatectomy, 8 by surgical castration, and 7 by medical castration.


CONCLUSIONS
Some tumors may fail to be detected by TRUS needle biopsy. Serial or multi-core needle biopsies can decrease the omission rate in the diagnosis of organ confined cancer.
Zhang
Shi-Wei
SW
Department of Urology, Nanjing Drum Tower Hospital, Nanjing University Medical College, Nanjing, Jiangsu 210008, China. zswzy456@sohu.com
Guo
Hong-Qian
HQ
Gan
Wei-Dong
WD
Gong
Zhen-Hua
ZH
Sun
Ze-Yu
ZY
D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000379:methods; D003951:Diagnostic Errors; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D012007:Rectum / Q000000981:diagnostic imaging; D020728:Transurethral Resection of Prostate; D018084:Ultrasonography, Interventional