Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human.
We report the initial sequencing and comparative analysis of the Macaca mulatta transcriptome. Cloned sequences from 11 tissues, nine animals, and three species (M. mulatta, M. fascicularis, and M. nemestrina) were sampled, resulting in the generation of 48,642 sequence reads. These data represent an initial sampling of the putative rhesus orthologs for 6,216 human genes. Mean nucleotide diversity within M. mulatta and sequence divergence among M. fascicularis, M. nemestrina, and M. mulatta are also reported.
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Charles L
CL
Magness
P Campion
PC
Fellin
Matthew J
MJ
Thomas
Marcus J
MJ
Korth
Michael B
MB
Agy
Sean C
SC
Proll
Matthew
M
Fitzgibbon
Christina A
CA
Scherer
Douglas G
DG
Miner
Michael G
MG
Katze
Shawn P
SP
Iadonato
D000818:Animals; D000465:Algorithms; D001483:Base Sequence; D003001:Cloning, Molecular; D030561:Databases, Nucleic Acid; D017931:DNA Primers; D018076:DNA, Complementary / Q000235:genetics; D019143:Evolution, Molecular; D015723:Gene Library; D014644:Genetic Variation; D008252:Macaca fascicularis / Q000235:genetics; D008253:Macaca mulatta; D008254:Macaca nemestrina / Q000235:genetics; D020411:Oligonucleotide Array Sequence Analysis; D012689:Sequence Homology, Nucleic Acid; D014158:Transcription, Genetic; D006801:Humans
D017931:DNA Primers; D018076:DNA, Complementary