Limbal allograft, amniotic membrane transplantation, and intraoperative mitomycin C for recurrent pterygium.
OBJECTIVE
To conduct a pilot study evaluating the efficacy and safety of limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C treatment for recurrent pterygium.


METHODS
Prospective, noncomparative, interventional case series.


METHODS
Twelve eyes of 11 patients with recurrent pterygium. The mean number of previous surgeries for pterygium was 1.9+/-1.4 (range, 1-6).


METHODS
All subjects received limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C.


METHODS
Pterygium recurrence and complications.


RESULTS
The mean follow-up period was 21.6+/-5.6 months (range, 16-36 months). There was no pterygium recurrence in any of the eyes. Symblepharon reappeared in 3 eyes and diplopia recurred in 2 eyes. There were no other surgical complications and there was no graft rejection.


CONCLUSIONS
Limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C may be a safe and effective procedure for recurrent pterygium.
Miyai
Takashi
T
Miyata Eye Hospital, Tokyo, Japan.
Hara
Ryuhei
R
Nejima
Ryohei
R
Miyata
Kazunori
K
Yonemura
Takaharu
T
Amano
Shiro
S
D000368:Aged; D000650:Amnion / Q000637:transplantation*; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage*; D017690:Cell Transplantation; D003131:Combined Modality Therapy; D004847:Epithelial Cells / Q000637:transplantation*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D016850:Limbus Corneae / Q000166:cytology*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*; D010865:Pilot Projects; D011183:Postoperative Complications; D011446:Prospective Studies; D011625:Pterygium / Q000188:drug therapy* / Q000601:surgery*; D012008:Recurrence; D012449:Safety; D014021:Tissue Preservation; D014184:Transplantation, Homologous; D016896:Treatment Outcome
D000903:Antibiotics, Antineoplastic; D016685:Mitomycin