Effects of the insoluble fiber derived from Passiflora edulis seed on plasma and hepatic lipids and fecal output.
The influence of the insoluble fiber-rich fraction (FRF) prepared from defatted Passiflora edulis seed, a potential fiber source, on plasma and hepatic lipids and fecal output were investigated in hamsters fed a hypercholesterolemic diet containing 5% insoluble FRF. The results showed that the consumption of insoluble FRF diet relative to cellulose diet could effectively (P < 0.05) decrease the levels of serum triglyceride, serum total cholesterol, and liver cholesterol, and increase (P < 0.05) the levels of total lipids, cholesterol, and bile acids in feces. The consumption of insoluble FRF also increased (P < 0.05) the fecal bulk and moisture. The marked cholesterol- and lipid-lowering effects of insoluble FRF might be partly attributed to its ability to enhance the excretion of lipids and bile acids via feces. Our results suggested that insoluble FRF could be a potential hypocholesterolemic ingredient for fiber-rich functional foods, but some further researches in humans may be needed to confirm its benefits.
Chau
Chi-Fai
CF
Department of Food Science, National Chung Hsing University, Taichung, Taiwan. chaucf@dragon.nchu.edu.tw
Huang
Ya-Ling
YL
D000818:Animals; D000924:Anticholesteremic Agents; D001647:Bile Acids and Salts / Q000032:analysis; D002482:Cellulose / Q000008:administration & dosage / Q000494:pharmacology; D002784:Cholesterol / Q000032:analysis / Q000097:blood; D006224:Cricetinae; D004043:Dietary Fiber / Q000008:administration & dosage / Q000494:pharmacology*; D005243:Feces / Q000737:chemistry; D008055:Lipids / Q000032:analysis* / Q000097:blood; D008099:Liver / Q000737:chemistry*; D008647:Mesocricetus; D029598:Passiflora / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry*; D012995:Solubility; D014280:Triglycerides / Q000097:blood
D000924:Anticholesteremic Agents; D001647:Bile Acids and Salts; D004043:Dietary Fiber; D008055:Lipids; D014280:Triglycerides; D002482:Cellulose; D002784:Cholesterol