Organocatalytic asymmetric direct alkylation of alpha-diazoester via C-H bond cleavage.
A new variant of phosphoric acid-catalyzed C-C bond forming reaction, direct alkylation of alpha-diazoester, via C-H bond cleavage is presented. The resulting products, beta-amino-alpha-diazoesters, are highly functionalized and useful synthetic precursors for various types of beta-amino acids.
Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan.
Daisuke
D
Uraguchi
Keiichi
K
Sorimachi
Masahiro
M
Terada