Acute pancreatitis in patients with ulcerative colitis.
Twenty-two patients (13 men and 9 women; median age, 34 years; range, 15-64 years) with ulcerative colitis (UC) were evaluated to determine the incidence of acute pancreatitis with UC at the First Department of Internal Medicine, Mie University School of Medicine, during 1989-2001. Among these, three patients (14%) were diagnosed as having had episodes of acute pancreatitis during the mean follow-up period of 6 years. One patient presented with acute pancreatitis and UC simultaneously. Two patients had drug-induced pancreatitis (one due to azathioprine and the other due to 5-ASA). In conclusion, acute pancreatitis is not a frequent, but an occasional extraintestinal manifestation of UC.
First Department of Internal Medicine, Mie University School of Medicine, Tsu, Mie 514-8507, Japan.
Hidekazu
H
Inoue
Katsuya
K
Shiraki
Hiroshi
H
Okano
Masatoshi
M
Deguchi
Takenari
T
Yamanaka
Takahisa
T
Sakai
Shigeru
S
Ohmori
Hitoshi
H
Yoshimura
Takeshi
T
Nakano
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000009:adverse effects; D003093:Colitis, Ulcerative / Q000150:complications*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000453:epidemiology* / Q000209:etiology*
D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents