[Cerebral perfusion in patients with metabolic syndrome].
Cerebral perfusion was studied in patients with arterial hypertension combined with metabolic syndrome and diabetes mellitus type II. The data is compared to the results obtained for patients with a single disorder--metabolic syndrome, diabetes mellitus type II and arterial hypertension without metabolic alterations. It is shown that patients with disregulation of carbohydrate and lipid metabolism are more vulnerable to cerebral blood supply alterations. A level of perfusion was the same in patients with metabolic syndrome and diabetes mellitus type II. Besides, an acetazolamide application revealed that patients with metabolic syndrome had reduced cerebral vascular autoregulation.
Chazova
I E
IE
Mychka
V B
VB
Gornostaev
V V
VV
Dvoskina
I M
IM
Sergienko
V B
VB
D000086:Acetazolamide / Q000493:pharmacokinetics; D000328:Adult; D001921:Brain / Q000098:blood supply / Q000378:metabolism / Q000503:physiopathology; D002257:Carbonic Anhydrase Inhibitors / Q000493:pharmacokinetics; D002560:Cerebrovascular Circulation / Q000502:physiology; D002561:Cerebrovascular Disorders / Q000150:complications* / Q000503:physiopathology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000175:diagnosis; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000503:physiopathology; D006973:Hypertension / Q000150:complications / Q000503:physiopathology; D007333:Insulin Resistance; D008297:Male; D008659:Metabolic Diseases / Q000150:complications* / Q000175:diagnosis; D013577:Syndrome
D002257:Carbonic Anhydrase Inhibitors; D000086:Acetazolamide