Mastitis in early infancy.
OBJECTIVE
To evaluate the clinical features and microbiological findings in young infants with mastitis.


METHODS
Retrospective review of medical records of 18 infants with breast inflammation during the first 3 mo of life seen in the paediatric emergency department between 1992 and 2002.


RESULTS
All were full-term infants with female-male ratio of 3.5:1. The age ranged from 12 to 45 d, with a peak in the 4th and 5th weeks of life. Only five patients had systemic manifestations, and five were pretreated with oral antibiotics (amoxicillin-clavulanic acid). The latter as well as seven additional cases required incision and drainage due to abscess formation. Bacterial cultures grew Staphylococcus aureus in 10 cases including all pretreated infants. In four of these cases, Gram stain showed the pathogen. After antimicrobial treatment, no recurrence was observed in any of the patients.


CONCLUSIONS
These findings suggest that mastitis in early infancy should be treated with parenteral antibiotics guided by Gram stain when available and informative. Otherwise, beta-lactamase-resistant antibiotics are a reasonable empirical initial treatment pending culture results. Optimizing the management of infants with mastitis is important especially since abscess formation requiring incision may be detrimental for later breast development.
University Children's Hospital, Zurich, Switzerland. tamar.stricker@kispi.unizh.ch
T
T
Stricker
F
F
Navratil
F H
FH
Sennhauser
D000038:Abscess / Q000628:therapy; D017677:Age Distribution; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D005840:Gentian Violet; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008413:Mastitis / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology / Q000628:therapy; D010619:Phenazines; D012189:Retrospective Studies; D013557:Switzerland / Q000453:epidemiology
D000900:Anti-Bacterial Agents; C035863:Gram's stain; D010619:Phenazines; D005840:Gentian Violet