Adenocarcinoma of the pancreas--past, present and future.
Adenocarcinoma of the pancreas has always been a disease with a dismal prognosis. Almost every patient with this cancer dies of the tumor. Over the years there has been extensive advancement in the understanding of etiology, molecular biology, diagnosis and treatment of this disease. Presently, surgical resection is the only potentially curative option available for these patients. It is now clear that surgery alone cannot increase the survival of these patients. With the understanding of molecular biology of pancreatic cancer new management strategies are under a preclinical stage of development. These new diagnostic and therapeutic modalities hopefully will improve the outcome of patients with pancreatic cancer.
Lygidakis
N J
NJ
Department of Surgical Oncology, Henry Dunant Hospital, Athens, Greece. iasg@iasg.org
Jain
Sundeep
S
Sacchi
Marco
M
Vrachnos
P
P
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D003131:Combined Modality Therapy / Q000639:trends; D003938:Diagnostic Techniques, Digestive System / Q000639:trends; D013505:Digestive System Surgical Procedures / Q000639:trends; D006801:Humans; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*