Three cases of anicteric leptospirosis from Turkey: mild to severe complications.
Leptospirosis is an acute generalized infectious disease, caused by spirochaetes, Leptospira interrogans. The severity of the disease ranges from an asymptomatic subclinical course to a fatal outcome. The three cases presented here were diagnosed serologically and had thrombocytopenia and acute renal failure as complication of anicteric leptospirosis. Our first case admitted with clinical presentation of pneumonia but clinical progress and laboratory findings made us to consider leptospirosis. The other two cases presented with aseptic meningitis were diagnosed as anicteric leptospirosis by the serological test results. One of the cases had fatal outcome but could not be strictly correlated with leptospirosis.
Department of Infectious Diseases and Clinical Microbiology, Ankara Training and Research Hospital, Ulucanlar, Ankara, Turkey. seberd@hotmail.com
F Sebnem
FS
Erdinc
Suda Tekin
ST
Koruk
Cigdem Ataman
CA
Hatipoglu
Sami
S
Kinikli
Ali Pekcan
AP
Demiroz
D058186:Acute Kidney Injury / Q000209:etiology*; D000212:Acyclovir / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D000372:Agglutination Tests; D000667:Ampicillin / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000907:Antibodies, Bacterial / Q000097:blood; D002443:Ceftriaxone / Q000008:administration & dosage; D017291:Clarithromycin / Q000008:administration & dosage; D004318:Doxycycline / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D017984:Enoxaparin / Q000008:administration & dosage; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007921:Leptospira interrogans / Q000276:immunology / Q000302:isolation & purification*; D007922:Leptospirosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D013921:Thrombocytopenia / Q000209:etiology*; D014421:Turkey
D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D017984:Enoxaparin; D002443:Ceftriaxone; D000667:Ampicillin; D017291:Clarithromycin; D004318:Doxycycline; D000212:Acyclovir