Treatment strategies for mares with placentitis.
Equine placentitis, and resultant preterm labor, are important sources of fetal and neonatal loss. The primary cause of equine placentitis is infection of the placenta with Streptococcus equi subspecies zooepidemicus, which ascends through the caudal reproductive tract. Current treatment protocols for mares affected with placentitis are empirical. This paper reviews treatment approaches for resolving placentitis and preterm labor in both equine and non-equine species. Specific therapies reviewed include antimicrobial, anti-inflammatory, tocolytic, and progestin agents.
College of Veterinary Medicine, Department of Large Animal Clinical Sciences, University of Florida, P.O. Box 100136, Gainesville, FL 32610, USA. macphersonm@mail.vetmed.ufl.edu
Margo L
ML
Macpherson
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy; D005260:Female; D006734:Horse Diseases / Q000382:microbiology / Q000628:therapy*; D006736:Horses; D007752:Obstetric Labor, Premature / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary; D010922:Placenta Diseases / Q000382:microbiology / Q000628:therapy / Q000662:veterinary*; D011247:Pregnancy; D015149:Tocolytic Agents / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D015149:Tocolytic Agents