[Gene targeting approaches for diabetes research].
Ohsugi
Mitsuru
M
Department of Metabolic Diseases, Graduate School of Medicine, The University of Tokyo.
Tobe
Kazuyuki
K
Kubota
Tetsuya
T
Kubota
Naoto
N
Terauchi
Yasuo
Y
Kadowaki
Takashi
T
D000818:Animals; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology*; D004195:Disease Models, Animal; D004730:Endothelium, Vascular / Q000473:pathology / Q000503:physiopathology; D005786:Gene Expression Regulation; D018390:Gene Targeting / Q000379:methods*; D005818:Genetic Engineering / Q000379:methods; D006801:Humans; D007328:Insulin / Q000378:metabolism; D055504:Insulin Receptor Substrate Proteins; D007333:Insulin Resistance; D000078790:Insulin Secretion; D047908:Intracellular Signaling Peptides and Proteins; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D010750:Phosphoproteins / Q000235:genetics; D011972:Receptor, Insulin / Q000235:genetics
C526292:IRS1 protein, human; C526297:IRS2 protein, human; D007328:Insulin; D055504:Insulin Receptor Substrate Proteins; D047908:Intracellular Signaling Peptides and Proteins; C526295:Irs1 protein, mouse; C526298:Irs2 protein, mouse; D010750:Phosphoproteins; D011972:Receptor, Insulin