[Five-year follow up of lipid profile in children in the Rivas-Vaciamadrid study].
OBJECTIVE
To evaluate lipid balance in children after a 5-year follow-up and tracking between initial and final levels.


METHODS
Two hundred eighty-one children included in the Rivas-Vaciamadrid study were evaluated at the ages of 6 and 11 years. In all children, total cholesterol (TC), triglycerides (TG), high-density lipoprotein-cholesterol (HDL-C), and apoproteins A1 (Apo A) and B100 (Apo B) were measured. Low-density lipoprotein-cholesterol (LDL-C) was determined and the Apo B/Apo A, TC/HDL-C, and LDL-C/HDL-C ratios and the atherogenic index were calculated.


RESULTS
At 11 years of age, lipid balance was worse in girls than in boys. Levels of TG and HDL-C were significantly higher at the age of 11 years than those at the age of 6 years, but levels of the remaining variables analyzed were lower, except for Apo A and TC, which showed a non-significant increase. The correlation coefficients between values at the ages of 6 and 11 years were significant for all variables and the highest was LDL-C in girls (0.711). Kappa and Nishio tracking indexes were significant for all variables and were highest for the atherogenic index (0.431 and 6.71 respectively) and lowest for TG (0.129 and 2.85 respectively). Subjects in the highest quartile at 6 years old had a relative risk of 8.04 (CI 4.34-14.88) for having the same atherogenic index at the age of 11 years and a relative risk of 1.91 (CI 1.05-3.46) for having the same TG value.


CONCLUSIONS
There is a significant correlation between lipid profile values in children at the ages of 6 and 11 years. The best tracking was found in the atherogenic index.
Grupo de Trabajo sobre Factores de Riesgo Cardiovascular en la Infancia y Adolescencia, Hospital Niño Jesús, Madrid, Spain. msanba@teleline.es
M
M
Sánchez-Bayle
A
A
Sánchez Bernardo
J
J
Asensio Antón
C
C
Ruiz-Jarabo Quemada
J
J
Baeza Mínguez
M T
MT
Morales San José
D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male
D008055:Lipids