Long-term use of silver containing nose-drops resulting in systemic argyria.
Generalized argyria is a silver intoxication that results in pigmentation due to deposition of silver in the skin and mucous membranes. Compared to several decades ago, argyria is now relatively rare. We report a case of generalized argyria after continous use of argyrophedrine nosedrops in the last ten years. Argyria should be taken into consideration when a patient presents with a blue-grey discoloration of the skin, particulary in areas exposed to the sun.
Department of Dermatology, University Hospital Antwerp, Belgium.
K
K
Van de Voorde
T
T
Nijsten
K
K
Schelfhout
G
G
Moorkens
J
J
Lambert
D001129:Argyria / Q000209:etiology*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008875:Middle Aged; D015508:Nasal Obstruction / Q000188:drug therapy; D018030:Silver Compounds / Q000008:administration & dosage* / Q000009:adverse effects*; D013997:Time Factors
D018030:Silver Compounds