A clinician's guide to the appropriate and accurate use of antibiotics: the Council for Appropriate and Rational Antibiotic Therapy (CARAT) criteria.
In response to the overuse and misuse of antibiotics, leading to increasing bacterial resistance and decreasing development of new antibiotics, the Council for Appropriate and Rational Antibiotic Therapy (CARAT) has developed criteria to guide appropriate and accurate antibiotic selection. The criteria, which are aimed at optimizing antibiotic therapy, include evidence-based results, therapeutic benefits, safety, optimal drug for the optimal duration, and cost-effectiveness.
Slama
Thomas G
TG
Department of Infectious Diseases, Indiana University School of Medicine, Indiana University, Indianapolis, Indiana, USA.
Amin
Alpesh
A
Brunton
Stephen A
SA
File
Thomas M
TM
Milkovich
Gary
G
Rodvold
Keith A
KA
Sahm
Daniel F
DF
Varon
Joseph
J
Weiland
David
D
D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000191:economics / Q000493:pharmacokinetics; D001424:Bacterial Infections / Q000188:drug therapy*; D003362:Cost-Benefit Analysis; D004363:Drug Utilization / Q000592:standards*; D006801:Humans; D018579:Patient Selection
D000900:Anti-Bacterial Agents