Paget-Schroetter syndrome in the young and active.
We report this case of effort thrombosis of the upper extremity (Paget-Schroetter syndrome) caused by hypertrophied muscles. This unusual cause of extrinsic venous compression and intimal injury leading to thrombosis was treated uniquely with good outcome. Untreated symptomatic patients can sustain long-term disability from venous obstruction resulting in significant loss of occupational productivity and quality of life. For the same reason, early catheter directed thrombolysis followed by anticoagulation and surgical intervention are recommended in much of the recent literature. Thrombolysis is the most common form of treatment, followed by surgery, if needed, after careful diagnostic approach. A majority of the literature supports a multimodal approach, but there is no definite consensus on management. This highlights the need for randomized clinical trials to guide management as well as to assess the safety and efficacy of anticoagulants commonly used and to define the optimal duration of therapy after thrombolysis.
Vijaysadan
Viju
V
Department of Medicine, Overlook Hospital, Summit, New Jersey 07901, USA. viju@earthlink.net
Zimmerman
Aphrodite M
AM
Pajaro
Rafael E
RE
D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D001132:Arm; D015444:Exercise; D006801:Humans; D008297:Male; D009515:New Jersey; D011859:Radiography; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology*
D000925:Anticoagulants