N-[tert-Butoxycarbonylglycyl-(Z)-alpha,beta-dehydrophenylalanylglycyl-(E)-alpha,beta-dehydrophenylalanylphenylalanyl]-4-nitroaniline ethanol solvate.
The alpha,beta-dehydrophenylalanine residues influence the conformation of the title pentapeptide Boc0-Gly1-Delta(Z)Phe2-Gly3-Delta(E)Phe4-L-Phe5-p-NA ethanol solvate, C42H43N7O9.C2H5OH. The first unsaturated phenylalanyl (Delta(Z)Phe2) and the third glycyl (Gly3) residues form a type I beta turn, while the second unsaturated phenylalanyl (Delta(E)Phe4) and the last phenylalanyl (L-Phe5) residues are part of a type II beta turn. All the amino acids in the peptide are linked trans to one another. The crystal structure is stabilized by intra- and intermolecular hydrogen bonds.
Makowski
Maciej
M
Institute of Chemistry, University of Opole, 48 Oleska Street, 45-052 Opole, Poland.
Brzuszkiewicz
Anna
A
Lisowski
Marek
M
Lis
Tadeusz
T
D000814:Aniline Compounds / Q000737:chemistry*; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D009842:Oligopeptides / Q000737:chemistry*
D000814:Aniline Compounds; C515428:N-(tert-butoxycarbonylglycyl-(Z)-alpha,beta-dehydrophenylalanylglycyl-(E)-alpha,beta-dehydrophenylalanylphenylalanyl)-4-nitroaniline; D009842:Oligopeptides