Not a new leukodystrophy but congenital cytomegalovirus infection.
We report a 16-month-old girl who presented with global developmental delay and hearing loss. Cranial magnetic resonance imaging demonstrated a pattern that could be interpreted as a "new leukoencephalopathy." Etiologic investigations revealed a positive polymerase chain reaction for cytomegalovirus DNA using her stored Guthrie card, indicating a congenital cytomegalovirus infection.
Tatli
Burak
B
Division of Child Neurology, Department of Pediatrics, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey. buraktat@yahoo.com
Ozmen
Meral
M
Aydinli
Nur
N
Caliskan
Mine
M
D001928:Brain Diseases, Metabolic / Q000175:diagnosis; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D002658:Developmental Disabilities / Q000209:etiology*; D003937:Diagnosis, Differential; D005260:Female; D034381:Hearing Loss / Q000209:etiology; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D016133:Polymerase Chain Reaction