Refractory polyarteritis nodosa successfully treated with infliximab.
We describe a woman with severe polyarteritis nodosa (PAN) with visceral involvement unresponsive to multiple immunosuppressive drugs. Infliximab treatment was very effective in this case. Infliximab may potentially be used as an alternative agent for the treatment of patients with PAN refractory to conventional therapy.
Division of Rheumatology, Department of Medicine, University of Western Ontario, London, Ontario, Canada.
Jamal
J
Al-Bishri
Nicole
N
le Riche
Janet E
JE
Pope
D000328:Adult; D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D018501:Antirheumatic Agents / Q000008:administration & dosage*; D004351:Drug Resistance; D005260:Female; D006801:Humans; D000069285:Infliximab; D007871:Leg Ulcer / Q000209:etiology / Q000473:pathology; D010488:Polyarteritis Nodosa / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D014945:Wound Healing
D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents; D000069285:Infliximab