[Clinical management of patients with short bowel syndrome].
Diarrhoea, malabsorption and malnutrition characterise the short bowel syndrome. The underlying gastrointestinal disorders, the types of intestinal resections performed and the subsequent pathophysiological situations are reviewed. Recommended therapeutic measures in the postoperative period as well as in the rehabilitation of patients with short bowel syndrome are discussed in more detail. In the postoperative period, parenteral nutrition is essential followed by an enteral diet to stimulate bowel adaptation, reduce fluid loss and increase nutrient absorption. The final diet should be based on the anatomy of the retained bowel (presence or absence of a colon and ileum). The importance of the colon as a digestive organ in patients with short bowel and the need of a low-oxalate diet are underlined. The possible benefit of new treatment options (glutamine, growth hormone and glucagon-like peptide 2) is discussed. Both typical complications of the short bowel syndrome and management of these complications are presented.
Leiss
O
O
OLeiss@aol.com
D003131:Combined Modality Therapy; D004750:Enteral Nutrition; D053767:Glucagon-Like Peptide 2; D004763:Glucagon-Like Peptides / Q000008:administration & dosage*; D005973:Glutamine / Q000008:administration & dosage*; D013006:Growth Hormone / Q000008:administration & dosage*; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects / Q000502:physiology; D007582:Jejunostomy; D010070:Oxalates / Q000008:administration & dosage*; D010289:Parenteral Nutrition, Total; D011183:Postoperative Complications / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D012778:Short Bowel Syndrome / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome; D014882:Water-Electrolyte Balance / Q000502:physiology
D053767:Glucagon-Like Peptide 2; D010070:Oxalates; D005973:Glutamine; D004763:Glucagon-Like Peptides; D013006:Growth Hormone