Gaining a solid grip on adipogenesis.
Obesity is presently being combated by fitness regimens, drugs and diet. Increasing our understanding of the physiology of adipocytes, by deducing the regulatory pathways involved in lipid metabolism and all aspects of adipogenesis, will provide alternative strategies to reduce adverse problems of obesity. Research has suggested that mature fat cells may dedifferentiate to form proliferative-competent fat cell precursors. Knowledge of the dedifferentiation process will allow us to gain a solid grip on adipogenesis.
Fernyhough
M E
ME
Muscle Biology Laboratory, Washington State University, Department of Animal Sciences, 139 Clark Hall, Pullman, WA 99164, USA.
Bucci
L R
LR
Hausman
G J
GJ
Antonio
J
J
Vierck
J L
JL
Dodson
M V
MV
D017667:Adipocytes / Q000166:cytology* / Q000502:physiology*; D002454:Cell Differentiation / Q000502:physiology; D049109:Cell Proliferation; D006801:Humans; D009765:Obesity / Q000503:physiopathology*