[Quantitative evaluation of acrylic and silicone intraocular lenses with a sharp optic edge design].
BACKGROUND
At the Department of Ophthalmology, Heidelberg, Germany, posterior capsule opacification (PCO) of a silicone and an acrylic intraocular lens (IOL) with a sharp optic edge design was evaluated.


METHODS
In a prospective study either the AMO ClariFlex silicone IOL or the Sensar AR40e hydrophobic acrylic IOL were implanted in 47 patients following uneventful phacoemulsification. Mean patient age was 76.2+/-7.8 (ClariFlex) and 73.4+/-12.9 years (AR40e), respectively. The mean follow-up time was 19.7+/-5.34 in the ClariFlex and 21.9+/-1.89 months in the AR40e group. PCO development was evaluated postoperatively using the EPCO 2000 analysis software (scale 0-4). Areas of interest were the total IOL optic, the central 3-mm zone as well as the capsulorhexis.


RESULTS
In both groups, all patients achieved a BCVA of 20/32 (AR40e) and 20/25 (ClariFlex), respectively. There was a very low incidence of PCO development with a mean EPCO score of 0.07+/-0.2 (ClariFlex and 0.15+/-0.2 (AR40e). Within the 3-mm zone and the capsulorhexis, there was a tendency for even lower EPCO scores in both groups. We calculated a statistically significant difference for the two lens materials for all investigated IOL areas (Wilcoxon's test, p<0.05).


CONCLUSIONS
Both IOLs with a sharp edge design showed good functional results, a stable position in the capsular bag as well as a low incidence of PCO development. However, the silicone IOL showed statistically significantly lower PCO scores.
Augenklinik, Universität, Heidelberg.
T M
TM
Rabsilber
A J
AJ
Reuland
B B
BB
Entz
M P
MP
Holzer
I J
IJ
Limberger
G U
GU
Auffarth
D000180:Acrylic Resins; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D003318:Corneal Opacity / Q000175:diagnosis / Q000453:epidemiology*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D005549:Foreign-Body Reaction / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007910:Lenses, Intraocular / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D055095:Optics and Photonics / Q000295:instrumentation; D017063:Outcome Assessment, Health Care; D018570:Risk Assessment; D012307:Risk Factors; D012828:Silicones; D016896:Treatment Outcome
D000180:Acrylic Resins; D012828:Silicones