[Severe dehydration and August 2003 heat wave in a cohort of adults with cystic fibrosis].
OBJECTIVE
To study dehydration related to the August 2003 heat wave in France in a cohort of adults with cystic fibrosis. Method Retrospective study of the telephone calls received from and hospital admissions of all adult cystic fibrosis patients (n=245) regularly followed in our specialized clinic.


RESULTS
Six patients developed extracellular dehydration with functional kidney failure concomitant to intracellular dehydration with hypokalemia and hypochloremia. Rehydration measures normalized the blood chemistry measures within 48 hours for all patients except one, who died of malignant hyperthermia.


CONCLUSIONS
In hot weather, it is essential for patients with cystic fibrosis to take measures (hydration, salt supplementation) to prevent severe dehydration.
Centre de ressources et de compétences de la mucoviscidose de l'adulte, service de pneumologie, Hôpital Cochin, Paris. nadine.desmazes-dufeu@cch.ap-hop-paris.fr
Nadine
N
Desmazes-Dufeu
Dominique
D
Hubert
Pierre-Régis
PR
Burgel
Reem
R
Kanaan
Valeria
V
Vélea
Daniel
D
Dusser
D058186:Acute Kidney Injury / Q000209:etiology*; D000328:Adult; D002712:Chlorides / Q000097:blood; D003550:Cystic Fibrosis / Q000150:complications*; D003681:Dehydration / Q000097:blood / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D004196:Disease Outbreaks; D004198:Disease Susceptibility; D005260:Female; D005440:Fluid Therapy; D006358:Hot Temperature / Q000009:adverse effects*; D006801:Humans; D007008:Hypokalemia / Q000453:epidemiology / Q000209:etiology; D008297:Male; D008305:Malignant Hyperthermia / Q000209:etiology / Q000401:mortality; D010297:Paris / Q000453:epidemiology; D010343:Patient Admission / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012621:Seasons; D013689:Telephone / Q000706:statistics & numerical data; D013696:Temperature; D014883:Water-Electrolyte Imbalance / Q000097:blood / Q000453:epidemiology / Q000209:etiology
D002712:Chlorides