A monoterpene glucoside and three megastigmane glycosides from Juniperus communis var. depressa.
A new monoterpene glucoside (1) and three new natural megastigmane glycosides (2-4) were isolated along with a known megastigmane glucoside (5) from twigs with leaves of Juniperus communis var. depressa (Cupressaceae) collected in Oregon, U.S.A., and their structures were determined on the basis of spectral and chemical evidence. In addition, the antibacterial activities of the isolated components against Helicobacter pylori were also investigated.
Nakanishi
Tsutomu
T
Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan. nakanisi@pharm.setsunan.ac.jp
Iida
Naoki
N
Inatomi
Yuka
Y
Murata
Hiroko
H
Inada
Akira
A
Murata
Jin
J
Lang
Frank A
FA
Iinuma
Munekazu
M
Tanaka
Toshiyuki
T
Sakagami
Yoshikazu
Y
D002236:Carbohydrate Conformation; D003512:Cyclohexanones / Q000302:isolation & purification* / Q000494:pharmacology; D005960:Glucosides / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000302:isolation & purification* / Q000494:pharmacology; D016480:Helicobacter pylori / Q000187:drug effects; D018653:Juniperus / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D039821:Monoterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D045792:Norisoprenoids / Q000302:isolation & purification* / Q000494:pharmacology
D003512:Cyclohexanones; D005960:Glucosides; D006027:Glycosides; D039821:Monoterpenes; D045792:Norisoprenoids; C413264:megastigmane