Primer of postoperative pruritus for anesthesiologists.
Postoperative itching is an important problem in the postoperative care unit. Pruritus after surgery may be drug induced (including intrathecal opioids) or secondary to a preexisting systemic disease. Mechanisms of itching are complex and not completely understood. The purpose of this review is to highlight new discoveries in pathways and mechanisms of pruritus and to summarize up-to-date knowledge about treatment of itching after surgery. More basic and clinical studies are needed to address the effects of drugs on specific receptors and improve the treatment of postoperative pruritus.
Waxler
Beverly
B
Department of Anesthesiology and Pain Management, John H. Stroger Jr. Hospital of Cook County, Chicago, Illinois 60612, USA. bwaxler@rush.edu
Dadabhoy
Zerin P
ZP
Stojiljkovic
Ljuba
L
Rabito
Sara F
SF
D000758:Anesthesia / Q000009:adverse effects*; D000776:Anesthesiology / Q000379:methods; D006801:Humans; D011183:Postoperative Complications / Q000139:chemically induced* / Q000517:prevention & control / Q000628:therapy; D011537:Pruritus / Q000139:chemically induced* / Q000517:prevention & control / Q000628:therapy