[Age and pathological features of 481 prostate cancer patients].
OBJECTIVE
To investigate the age and pathological features of prostate cancer patients in recent years.


METHODS
An analysis was made of the age and pathological features of 481 cases of prostate cancer pathologically diagnosed from January 1998 to April 2004, 39 cases in 1998, 69 in 1999, 73 in 2000, 68 in 2001, 72 in 2002, 121 in 2003, and 39 in the first four months of 2004.


RESULTS
The patients ranged in age from 40 to 91 years, averaging 72, 95% between 55 and 84, and 84.2% over 65 years. Pathologically, 14 cases were well, 29 moderately, and 83 poorly differentiated according to the three-grade system (WHO, the Mostofi system), with 355 cases ungraded. Forty cases (8.3%) were microcarcinoma (< 1 cm), and 20 cases (4.2%) incidental carcinoma. Of the total number, 473 cases (98.1%) were pathologically diagnosed as adenocarcinoma, 1 endometrioid adenocarcinoma, 1 squamous cell carcinoma, 1 signet ring cell carcinoma, 1 adenosquamous cell carcinoma, 1 small cell carcinoma, 1 mucinous adenocarcinoma, 1 adenoid cystic carcinoma, and 1 transitional cell carcinoma.


CONCLUSIONS
Prostate cancer commonly develops in men over 65 years, and adenocarcinoma is the most common histological type. The disease has become a major malignant tumor to endanger elderly males.
Department of Urology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China. xielp@zjuem.zju.edu.cn
Li-Ping
LP
Xie
Jie
J
Qin
Xiang-Yi
XY
Zheng
Hua-Feng
HF
Shen
Zhao-Dian
ZD
Chen
Song-Liang
SL
Cai
Zhi-Gen
ZG
Zhang
Wei
W
Ding
Guo-Ping
GP
Ren
Li-Jun
LJ
Wang
Xin-Ru
XR
Yu
D000230:Adenocarcinoma / Q000473:pathology; D000328:Adult; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000473:pathology*