[The effect of bamboo leaves extract on hemorheology of normal rats].
Sixty rats were randomly divides into six groups. Blood stasis model was set up by sc isoprenaline, and different dose of BLE (15 mg/kg, 30 mg/kg and 60 mg/kg) were iv. The effects of BLE on rat's blood viscosity, plasma viscosity, FIB, ESR, TK, electrophoresis times and HCT were measured by automatic analysis system. Sixty mice were randomly divided into six groups, and the serum cholesterol of the high cholesterol's mice was obtained by eyepit vein and measured. The results showed that BLE (15 mg/kg, 30 mg/kg and 60 mg/kg) could reduce blood viscosity, plasma viscosity, FIB, ESR, TK, HCT and increase the speed of electrophoresis time in blood adhesion model, and BLE (22.5 mg/kg, 45 mg/kg, 90 mg/kg) could significantly reduce serum cholesterol of the high cholesterol's mice.
Department of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016.
Xiaochun
X
Fu
Minwei
M
Wang
Shaopeng
S
Li
Yanchun
Y
Li
D000818:Animals; D001799:Blood Sedimentation / Q000187:drug effects; D001809:Blood Viscosity / Q000187:drug effects* / Q000502:physiology; D002784:Cholesterol / Q000097:blood; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004903:Erythrocyte Aggregation / Q000187:drug effects; D005340:Fibrinogen / Q000187:drug effects; D006400:Hematocrit; D018056:Hemorheology / Q000187:drug effects*; D051379:Mice; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017207:Rats, Sprague-Dawley; D031787:Sasa / Q000737:chemistry*; D013927:Thrombosis / Q000139:chemically induced / Q000473:pathology
D004365:Drugs, Chinese Herbal; D005340:Fibrinogen; D002784:Cholesterol