Congenital cervical rhabdomyosarcoma arising in one fetus of a twin pregnancy.
OBJECTIVE
To describe a huge congenital cervical rhabdomyosarcoma.


METHODS
We were recently confronted with a case of fetal solid neck mass arising in one fetus of a twin pregnancy. Prenatally, the cervical tumor was consistent with teratoma, but it was diagnosed histologically as a rhabdomyosarcoma. Genetic amniocentesis showed a mosaic pattern consisting of 46,XY/46,XY,t(2;8)(q35;q21.2).


RESULTS
EXIT procedure was proposed to the parents but declined. The twin with huge cervical tumor died in utero at 35 weeks' gestation due to hydrops fetalis.


CONCLUSIONS
Fetal cervical rhabdomyosarcoma is an extremely rare condition that has not been previously reported, but should be considered in the presentation of fetal solid neck mass.
Yoshino
Kiyoshi
K
Department of Obstetric, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan. yoshino@gyne.med.osaka-u.ac.jp
Takeuchi
Makoto
M
Nakayama
Masahiro
M
Suehara
Noriyuki
N
D000328:Adult; D004200:Diseases in Twins / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology*; D005260:Female; D005313:Fetal Death; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology*; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology*; D006801:Humans; D011247:Pregnancy; D012208:Rhabdomyosarcoma / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology*; D014427:Twins; D016216:Ultrasonography, Prenatal