Chlordiazepoxide-induced Stevens-Johnson syndrome.
The causes of Stevens-Johnson syndrome (SJS) can be categorized as iatrogenic, infectious or idiopathic. Drug-induced SJS is associated with various antibiotics, anticonvulsants, and other drugs. However, no previous reports have mentioned an association between chlordiazepoxide, a benzodiazepine sedative, and SJS. Here, we present a case of SJS induced by chlordiazepoxide overdose. This case reminds us that SJS may be an adverse effect of chlordiazepoxide. Further, overdosage with benzodiazepine sedatives should be added to the list of potential causes of SJS.
Huang
Po-Hsun
PH
Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C. huangbs@vghtpe.gov.tw
Tsai
Wei-Jen
WJ
D000328:Adult; D002707:Chlordiazepoxide / Q000009:adverse effects*; D006801:Humans; D008297:Male; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced* / Q000628:therapy
D002707:Chlordiazepoxide