Transarterial chemoembolization in the treatment of hepatoblastoma in children.
Hepatoblastoma is one of the clinical challenges in children, as it is common and frequently unresectable. Chemotherapy can be administered regionally instead of systemically by transarterial chemoembolization (TACE) and thus improve prognosis. The advantages of this technique over systemic chemotherapy led to developing its role from being a palliative or an adjuvant preoperative treatment to being a potentially independent palliative or curative therapeutic option. The technical aspects and complications of a combined transarterial administration of chemotherapeutic and vascular occlusive agents in cases of hepatoblastoma in children are discussed, to give a comprehensive idea about the value of TACE in this context.
Department of Diagnostic and Interventional Radiology, University of Frankfurt/Main, Theodor-Stern-Kai, 60590 Frankfurt/Main, Germany. T.Vogl@em.uni-frankfurt.de
Thomas J
TJ
Vogl
Albert
A
Scheller
Ursula
U
Jakob
Stefan
S
Zangos
Medhat
M
Ahmed
Mohamed
M
Nabil
D000293:Adolescent; D000970:Antineoplastic Agents / Q000008:administration & dosage; D016461:Chemoembolization, Therapeutic / Q000009:adverse effects / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D003287:Contrast Media; D018197:Hepatoblastoma / Q000628:therapy*; D006801:Humans; D007459:Iodized Oil; D008113:Liver Neoplasms / Q000628:therapy*
D000970:Antineoplastic Agents; D003287:Contrast Media; D007459:Iodized Oil