Ontogeny of cortical synaptic depression underlying olfactory sensory gating in the rat.
Sensory gating is the ability to filter irrelevant or redundant sensory input and is a critical function of all sensory systems that allows efficient processing of important stimuli. The present results demonstrate that a form of activity-dependent synaptic depression recently found to be involved in both cortical and behavioral olfactory sensory gating, is functional by at least the first postnatal week in the rat piriform cortex, and shares a common metabotropic glutamate receptor mechanism.
Department of Zoology, University of Oklahoma, Norman, OK 73019, USA.
Jason V
JV
Thompson
Aaron R
AR
Best
Donald A
DA
Wilson
D000818:Animals; D000831:Animals, Newborn; D004558:Electric Stimulation / Q000379:methods; D018691:Excitatory Amino Acid Antagonists / Q000494:pharmacology; D005998:Glycine / Q000031:analogs & derivatives / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D009433:Neural Inhibition / Q000187:drug effects / Q000502:physiology* / Q000528:radiation effects; D009833:Olfactory Pathways / Q000187:drug effects / Q000502:physiology* / Q000528:radiation effects; D051381:Rats; D020318:Rats, Long-Evans; D013569:Synapses / Q000187:drug effects / Q000502:physiology* / Q000528:radiation effects; D009435:Synaptic Transmission / Q000187:drug effects / Q000502:physiology* / Q000528:radiation effects; D013997:Time Factors
D018691:Excitatory Amino Acid Antagonists; C104331:cyclopropyl-4-phosphonophenylglycine; D005998:Glycine