Clinical misdiagnosis of solid pseudopapillary tumour of pancreas.
BACKGROUND
Since being reclassified by WHO in 1996, solid pseudopapillary tumour (SPT) of pancreas has been recognized as the internationally accepted name. Clinicians are lacking in knowledge of this rare disease so the misdiagnosis and inappropriate therapy are hard to avoid. The clinic data on 22 patients were summarized to study the misdiagnosis and treatment of a sample of SPTs.


METHODS
Twenty-two female patients with SPT were studied retrospectively and divided into two groups, the misdiagnosed group and the correctly diagnosed one. The analyses were performed with Fisher test with accurate probability for categorical data, and Kruskal-Wallis test for ranked data.


RESULTS
The rate of misdiagnosis in this sample was 45.5%. The misdiagnosed SPTs were apt to be the incomplete capsule ones (P = 0.020), which resulted in obvious difficulties during operation (P = 0.024). In the misdiagnosed SPT group, the medical expenses increased significantly (P = 0.042), and the number of days in hospital greater than in correctly diagnosed group (P = 0.041).


CONCLUSIONS
Although SPT has low malignancy with excellent prognosis after surgical treatment in most patients, the misdiagnosis of SPT increases the social and economic burdens on patients. It is important to analyse the causes of misdiagnosis.
Cheng
Dong-feng
DF
Centre of Organ Transplantation, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China.
Peng
Cheng-hong
CH
Zhou
Guang-wen
GW
Tao
Zong-yuan
ZY
Chen
Xi
X
Lei
Ruo-qing
RQ
Zhang
Sheng-dao
SD
Li
Hong-wei
HW
D000293:Adolescent; D000328:Adult; D002291:Carcinoma, Papillary / Q000175:diagnosis* / Q000601:surgery; D002648:Child; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000601:surgery