Divalent ligand for intramolecular complex formation to streptavidin.
Monovalent ligand and divalent ligand have been synthesized, and their thermodynamic parameters of complexation to avidin and streptavidin have been analyzed in terms of multivalent binding.
Departament de Quimica Organica, Universitat de Barcelona, Martí i Franqués 1, 08028, Barcelona, Spain. jfarrera@ub.edu
Joan-Antoni
JA
Farrera
Pedro
P
Hidalgo-Fernández
Jurry M
JM
Hannink
Jurriaan
J
Huskens
Alan E
AE
Rowan
Nico A J M
NA
Sommerdijk
Roeland J M
RJ
Nolte
D001360:Avidin / Q000737:chemistry; D002413:Cations, Divalent / Q000138:chemical synthesis*; D008024:Ligands; D011485:Protein Binding; D019809:Streptavidin / Q000138:chemical synthesis* / Q000737:chemistry; D013816:Thermodynamics
D002413:Cations, Divalent; D008024:Ligands; D001360:Avidin; D019809:Streptavidin