[Diabetes Type I therapy through transplantation].
Diabetes is one of the most common chronic diseases in our society. While insulin treatment for diabetes type I could delay and reduce the incidence of diabetic complications, it is associated with an increased risk of severe hypoglycemia. To restore physiologic insulin metabolism, transplantation of insulin producing cells (pancreatic Beta cells) represent the sole available therapy. It could be done either through pancreas or islet of Langerhans transplantation. In this paper, we review actual knowledge regarding these two types of transplantations.
Département de chirurgie, service de chirurgie viscérale et de transplantation, hôpitaux universitaires de Genève, 24 rue Micheli-Du-Crest, 1211 Geneva 14, Switzerland. Pascal.Bucher@hcuge.ch
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P
Bucher
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Mathe
L H
LH
Buhler
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A
Andres
D
D
Bosco
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T
Berney
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P
Morel
D003922:Diabetes Mellitus, Type 1 / Q000628:therapy*; D006801:Humans; D016381:Islets of Langerhans Transplantation; D016035:Pancreas Transplantation