[Some principles in the organization of sigma70-specific promoters on the E. coli genome on the basis of electrostatic patterns of promoter DNA].
The distribution of electrostatic potential of the complete sequence of the E. coli genome was calculated. It was found that DNA is not a uniformly charged molecule. There are some local inhomogeneities in its electrostatic profile, which correlate with the position of promoters in the genome. Electrostatic patterns of promoter DNAs can be specified due to the presence of some distinctive motifs, which may be involved as promoter signal elements in RNA-polymerase-promoter recognition.
S G
SG
Kamzolova
A A
AA
Sorokin
A A
AA
Osipov
P M
PM
Beskaravaĭnyĭ
D012321:DNA-Directed RNA Polymerases / Q000235:genetics*; D048168:Escherichia coli K12 / Q000235:genetics*; D016680:Genome, Bacterial; D011401:Promoter Regions, Genetic; D012808:Sigma Factor / Q000235:genetics*; D055672:Static Electricity; D014158:Transcription, Genetic / Q000235:genetics
D012808:Sigma Factor; C081775:RNA polymerase sigma 70; D012321:DNA-Directed RNA Polymerases