An update on the functional molecular immunology (FIMM) database.
Data on the major histocompatibility complex, T-cell epitopes, B-cell epitopes, antigens and diseases are heterogeneous and scattered among different databases and the literature. Since it has become increasingly difficult to obtain an integrated view of functional immune response components, we have developed and updated over several years the Functional molecular IMMunology (FIMM) database (http:// research.i2r.a-star.edu.sg/fimm/). FIMM contains integrated expert-curated data on protein antigens, and on human immunological receptors that recognise and bind them in healthy or disease states. Interfaces with multiple, intuitive query options and query reports provide immunologists with prioritised information that aids data interpretation, vaccine target discovery and immune disease research.
Knowledge Discovery Department, Institute for Infocomm Research, Singapore.
Christian
C
Schönbach
Judice L Y
JL
Koh
Darren R
DR
Flower
Vladimir
V
Brusic
D000486:Allergy and Immunology / Q000639:trends; D000937:Antigen-Antibody Reactions / Q000235:genetics / Q000276:immunology*; D000941:Antigens / Q000737:chemistry / Q000235:genetics / Q000276:immunology*; D003628:Database Management Systems; D016208:Databases, Factual; D007158:Immunologic Techniques / Q000639:trends; D016247:Information Storage and Retrieval / Q000379:methods* / Q000639:trends; D008967:Molecular Biology / Q000379:methods*; D011506:Proteins / Q000737:chemistry / Q000235:genetics / Q000276:immunology*
D000941:Antigens; D011506:Proteins