Frequent detection of Epstein-Barr Virus and cytomegalovirus but not JC virus DNA in cerebrospinal fluid samples from human immunodeficiency virus-infected patients in northern Thailand.
Applying nested-PCRs, we frequently detected DNA of Epstein-Barr virus and cytomegalovirus but not JC virus in cerebrospinal fluid samples from 140 human immunodeficiency virus-infected patients with central nervous system symptoms in northern Thailand. Despite the low incidence of primary central nervous system lymphoma or cytomegalovirus encephalitis among Thai AIDS patients, Epstein-Barr virus and cytomegalovirus infections in the central nervous system are common.
National Institute of Health, Department of Medical Sciences, Nonthaburi, Thailand.
Archawin
A
Rojanawiwat
Toshiyuki
T
Miura
Hansa
H
Thaisri
Panita
P
Pathipvanich
Sittichai
S
Umnajsirisuk
Tomohiko
T
Koibuchi
Suthon
S
Vongsheree
Aikichi
A
Iwamoto
Koya
K
Ariyoshi
Pathom
P
Sawanpanyalert
D000328:Adult; D020805:Central Nervous System Viral Diseases / Q000150:complications / Q000821:virology*; D002555:Cerebrospinal Fluid / Q000821:virology*; D003587:Cytomegalovirus / Q000235:genetics / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000150:complications / Q000821:virology; D004279:DNA, Viral / Q000032:analysis*; D020031:Epstein-Barr Virus Infections / Q000150:complications / Q000821:virology; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000821:virology; D015497:HIV-1; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D007577:JC Virus / Q000235:genetics; D008297:Male; D013785:Thailand
D004279:DNA, Viral