Sphenoid wing meningiomas with osseous involvement.
BACKGROUND
Sphenoid wing meningiomas (SWMs) with osseous involvement are neurosurgically challenging because of their position within the skull base and their high rates of recurrence. Sufficient resection of these meningiomas requires extensive surgical exposure. We report on 82 patients with meningiomas infiltrating the sphenoid wing, analyzing radiological appearance and its influence on surgical management.


METHODS
Charts of the patients including surgical records, clinical reports, histological examinations, imaging studies, and meticulously focusing questionnaires were reviewed.


RESULTS
Among the 82 patients with osseous-involved SWMs, the mean age was 52.2 years in the female group and 54.7 years in the male group with a mean follow-up of 66.23 months (24-206). Histological evaluation revealed World Health Organization grade I meningiomas in 94% of case patients, tumor infiltration of examined bone in all case patients, and proliferation rates of 2.2% Ki-67. Magnetic resonance imaging appearance of the SWMs demonstrated various densities as well as Gd enhancement within the affected bone. Recurrence rates in this subgroup of SWMs are higher (>30%) compared with meningiomas without osseous involvement (11.6%).


CONCLUSIONS
Osseous involvement in SWMs accounts for lower resection and higher recurrence rates than meningiomas in other locations. In those cases with involvement of the cavernous sinus, a subtotal but extensive removal combined with bony decompression of the cranial nerves at the superior orbital fissure and optic canal frequently produces good functional and cosmetic results.
Department of Neurosurgery, Klinikum Hannover Nordstadt, 30167 Hannover, Germany. f.roser@gmx.de
Florian
F
Roser
Makoto
M
Nakamura
Cornelius
C
Jacobs
Peter
P
Vorkapic
Madjid
M
Samii
D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D008579:Meningioma / Q000000981:diagnostic imaging* / Q000601:surgery*; D008875:Middle Aged; D011859:Radiography; D012189:Retrospective Studies; D013100:Sphenoid Bone