Liver transplantation for cardiac failure in patients with hereditary hemorrhagic telangiectasia.
Liver involvement in hereditary hemorrhagic telangiectasia may lead to high-output cardiac failure. Few data have been reported on orthotopic liver transplantation (OLT) for these patients. In this paper, we describe two patients treated by OLT as a salvage procedure for cardiac failure, and we review literature on this subject. Our two patients resumed normal cardiac function after OLT. This procedure appears to be a promising therapy with good long-term results despite dissection difficulties encountered due to the collateral arterial network reorganization.
Hepatology Unit, Hôpital Jean Minjoz, Besançon, France.
Thierry
T
Thevenot
Hepatology Unit, Hôpital Jean Minjoz, Besançon, France.
Claire
C
Vanlemmens
Hepatology Unit, Hôpital Jean Minjoz, Besançon, France.
Vincent
V
Di Martino
Hepatology Unit, Hôpital Jean Minjoz, Besançon, France.
Marie-Claude
MC
Becker
Digestive Surgery Unit, Hôpital Jean Minjoz, Besançon, France.
Pierre-Olivier
PO
Denue
Department of Pathology, Hôpital Jean Minjoz, Besançon, France.
Bernadette
B
Kantelip
Hepatology Unit, Hôpital Jean Minjoz, Besançon, France.
Solange
S
Bresson-Hadni
Digestive Surgery Unit, Hôpital Jean Minjoz, Besançon, France.
Bruno
B
Heyd
Digestive Surgery Unit, Hôpital Jean Minjoz, Besançon, France.
Georges
G
Mantion
Hepatology Unit, Hôpital Jean Minjoz, Besançon, France.
Jean-Philippe
JP
Miguet
D000792:Angiography; D016534:Cardiac Output, High / Q000209:etiology*; D005260:Female; D006499:Hepatic Artery / Q000000981:diagnostic imaging; D006503:Hepatic Veins / Q000000981:diagnostic imaging; D006801:Humans; D008107:Liver Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery*; D016031:Liver Transplantation; D008875:Middle Aged; D011860:Radiography, Abdominal; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome