Ustilagic acid secretion by Pseudozyma fusiformata strains.
Eight strains of Pseudozyma fusiformata were examined for antifungal activity. All of them had the same spectrum of action and were active against many species of yeasts, yeast-like and filamentous fungi. They secreted glycolipids, which were purified from the culture liquid by column and thin-layer chromatography. According to nuclear magnetic resonance and mass-spectroscopy experiments all strains produced ustilagic acid, a cellobioside-containing 2,15,16-trihydroxypalmitic acid as aglycon, 3-hydroxycaproic acid and acetic acid as O-acylic substituents.
Kulakovskaya
Tatiana V
TV
G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, 142290 Pushchino, Moscow region, Russia. alla@ibpm.pushchino.ru
Shashkov
Alexander S
AS
Kulakovskaya
Ekaterina V
EV
Golubev
Wladyslav I
WI
D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D002845:Chromatography; D006017:Glycolipids / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008970:Molecular Weight; D013045:Species Specificity; D015003:Yeasts / Q000254:growth & development / Q000378:metabolism*
D000935:Antifungal Agents; D006017:Glycolipids