A familial case of multicystic dysplastic kidney.
A familial case of multicystic dysplastic kidney (MCDK) is described. The proband is a one-year-old boy with left MCDK, and his father was also revealed to have unilateral MCDK. The mother had two abortions; the second pregnancy was terminated because of bilateral MCDK of the fetus (Potter anomaly). The two patients and the aborted male fetus did not have any malformations except for MCDK. Thus in this family MCDK occurs as an isolated phenomenon in three individuals within two generations, presumably as a result of autosomal dominant inheritance.
Sekine
Takashi
T
Department of Pediatrics, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655 Tokyo, Japan. sekinet-tky@umin.ac.jp
Namai
Yoshiyuki
Y
Yanagisawa
Atsuhiro
A
Shirahama
Hiroshi
H
Tashiro
Yukie
Y
Terahara
Masahito
M
Nagata
Michio
M
Harita
Yutaka
Y
Fukuoka
Utako
U
Inatomi
Jun
J
Igarashi
Takashi
T
D000328:Adult; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D007223:Infant; D008297:Male; D021782:Multicystic Dysplastic Kidney / Q000175:diagnosis* / Q000235:genetics*; D011247:Pregnancy; D016216:Ultrasonography, Prenatal