The role of cryopreservation for women prior to treatment of malignancy.
OBJECTIVE
The purpose of this review is to investigate recent advances in xenografting, as well as in orthotopic and heterotopic autotransplantation of human cryopreserved ovarian tissue.


RESULTS
The first livebirth after orthotopic transplantation of cryopreserved ovarian tissue was reported recently. We discuss this case and other cases of reimplantation of cryopreserved ovarian tissue, bearing in mind that many questions remain.


CONCLUSIONS
Finally, we report the latest developments in research on the transplantation of an intact ovary and the reimplantation of isolated follicles.
Department of Gynecology, Cliniques Universitaires St. Luc, Université Catholique de Louvain, Avenue Hippocrate, 10, B-1200 Brussels, Belgium. donnez@gyne.ucl.ac.be
Jacques
J
Donnez
Marie-Madeleine
MM
Dolmans
Belen
B
Martinez-Madrid
Dominique
D
Demylle
Anne
A
Van Langendonckt
D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects; D015925:Cryopreservation; D005260:Female; D006801:Humans; D009865:Oocytes; D010053:Ovary / Q000637:transplantation; D016042:Transplantation, Heterotopic; D016896:Treatment Outcome
D000970:Antineoplastic Agents