A monoterpene glucoside and three megastigmane glycosides from Juniperus communis var. depressa.
A new monoterpene glucoside (1) and three new natural megastigmane glycosides (2-4) were isolated along with a known megastigmane glucoside (5) from twigs with leaves of Juniperus communis var. depressa (Cupressaceae) collected in Oregon, U.S.A., and their structures were determined on the basis of spectral and chemical evidence. In addition, the antibacterial activities of the isolated components against Helicobacter pylori were also investigated.
Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan. nakanisi@pharm.setsunan.ac.jp
Tsutomu
T
Nakanishi
Naoki
N
Iida
Yuka
Y
Inatomi
Hiroko
H
Murata
Akira
A
Inada
Jin
J
Murata
Frank A
FA
Lang
Munekazu
M
Iinuma
Toshiyuki
T
Tanaka
Yoshikazu
Y
Sakagami
D002236:Carbohydrate Conformation; D003512:Cyclohexanones / Q000302:isolation & purification* / Q000494:pharmacology; D005960:Glucosides / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000302:isolation & purification* / Q000494:pharmacology; D016480:Helicobacter pylori / Q000187:drug effects; D018653:Juniperus / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D039821:Monoterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D045792:Norisoprenoids / Q000302:isolation & purification* / Q000494:pharmacology
D003512:Cyclohexanones; D005960:Glucosides; D006027:Glycosides; D039821:Monoterpenes; D045792:Norisoprenoids; C413264:megastigmane