[State of protease inhibitor system in patients with occupational bronchial asthma caused by nonferrous metal aerosols].
The article represents results of studies concerning biochemical features of inflammation in various types of bronchial asthma caused by nonferrous metal aerosols. Also parameters of "proteolysis--antiproteolysis" system were studied on molecular genetic and biochemical levels, with determining serine proteinase, level of protease alpha-1 inhibitor and its hyposecretory deficit variants, levels of individual proteins.
O I
OI
Rumiantseva
L P
LP
Kuz'mina
V N
VN
Ozhiganova
D000336:Aerosols / Q000009:adverse effects*; D001249:Asthma / Q000201:enzymology / Q000235:genetics / Q000503:physiopathology; D015415:Biomarkers; D006801:Humans; D008670:Metals / Q000009:adverse effects*; D009784:Occupational Diseases / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology; D009961:Orosomucoid / Q000235:genetics*; D010447:Peptide Hydrolases / Q000502:physiology*; D011480:Protease Inhibitors / Q000097:blood*; D012307:Risk Factors; D012697:Serine Endopeptidases / Q000378:metabolism*; D000511:alpha-Macroglobulins / Q000235:genetics*
D000336:Aerosols; D015415:Biomarkers; D008670:Metals; D009961:Orosomucoid; D011480:Protease Inhibitors; D000511:alpha-Macroglobulins; D010447:Peptide Hydrolases; D012697:Serine Endopeptidases