A case of multiple amoebic liver abscesses: clinical improvement after percutaneous aspiration.
Amoebic liver abscesses are by far the most common extra-intestinal manifestation of invasive amoebiasis. The classical clinical picture consists of fever, right upper quadrant pain and hepatomegaly. Ultrasound and serology make an early diagnosis possible. Amoebic liver abscesses usually appear singly and are normally situated in the right lobe of the liver. This case report refers to a white Belgian woman, living in an endemic area for amoebiasis, presenting with 25 amoebic liver abscesses, who did not improve clinically despite appropriate anti-amoebic therapy, is described. Only percutaneous drainage of the larger abscesses led to clinical recovery. Amoebic abscess aspiration and evacuation under ultrasonographic guidance is of limited risk, but in experienced hands may enhance clinical recovery, particularly in patients with large abscesses not responding to conservative medical treatment. Aspiration of large abscesses (> 5 cm) is rarely necessary but should be considered if there is no clinical improvement after 3 days of nitroimidazole treatment with amoebicides.
Departement Interne Geneeskunde, Universitair Ziekenhuis Gasthuisberg, Herestraat 49, B-3000 Leuven.
P
P
Soentjens
B
B
Ostyn
J
J
Clerinx
A
A
Van Gompel
R
R
Colebunders
D000328:Adult; D000563:Amebicides / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D004322:Drainage / Q000379:methods; D005260:Female; D006801:Humans; D008101:Liver Abscess, Amebic / Q000601:surgery*; D008795:Metronidazole / Q000627:therapeutic use; D017211:Treatment Failure
D000563:Amebicides; D000981:Antiprotozoal Agents; D008795:Metronidazole