[Telomerase and malignant tumors--diagnostic and prognostic role].
Telomerase synthesizes telomeric DNA repeats at the ends of eukaryotic chromosomes and inhibits of natural senescence of different cells. Its increased activity has been found in most malignant tumors. This article is a review on current knowledge about diagnostic and prognostic value of telomerase in malignancies.
Wojskowy Instytut Medyczny, Klinika Chorób Wewnetrznych, Pneumonologii i Alergologii CSK MON, Warszawa. targowski.tomasz@xl.wp.pl
Tomasz
T
Targowski
D014408:Biomarkers, Tumor / Q000378:metabolism*; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis* / Q000201:enzymology*; D011237:Predictive Value of Tests; D011379:Prognosis; D019098:Telomerase / Q000378:metabolism*
D014408:Biomarkers, Tumor; D019098:Telomerase