[Usefulness of adding antibiotic to cement in one stage exchange of chronic infection in total hip arthroplasty].
OBJECTIVE
Direct exchange using antibiotic-impregnated cement is a treatment option for hip prosthesis infection (HPI). Nevertheless, a local antibiotic use is not always possible. We present our experience with direct exchange with and without antibiotic-impregnated cement.


METHODS
Fourteen patients with a HPI were treated with direct exchange. The femoral component was cemented with an antibiotic in 7 cases and in 7 it was not cemented. The patients received antibiotic prophylaxis and antibiotic treatment for a mean of 3 months. Clinical evolution of the infection was prospectively assessed.


RESULTS
There were no differences with regard to the clinical and microbiologic characteristics between both groups. In the last control (minimum 2 years) all the patients were cured.


CONCLUSIONS
Our results suggest that direct exchange without local antibiotic is an option in HPI. Further studies are needed to evaluate the usefulness of antibiotic loaded cement.
Servicio de Cirugía Ortopédica y Traumatología, Hospital Clínic de Barcelona, IDIBAPS, Villariel 170, 08036 Barcelona, Spain. sgarcia@clinic.ub.es
Sebastián
S
García
Alex
A
Soriano
Pedro
P
Esteban
Manel
M
Almela
Xavier
X
Gallart
Josep
J
Mensa
D000368:Aged; D000369:Aged, 80 and over; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis / Q000379:methods*; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D001843:Bone Cements / Q000627:therapeutic use*; D002908:Chronic Disease; D005260:Female; D006622:Hip Prosthesis / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016459:Prosthesis-Related Infections / Q000188:drug therapy* / Q000382:microbiology; D012086:Reoperation
D000891:Anti-Infective Agents, Local; D001843:Bone Cements