BioLayout(Java): versatile network visualisation of structural and functional relationships.
Visualisation of biological networks is becoming a common task for the analysis of high-throughput data. These networks correspond to a wide variety of biological relationships, such as sequence similarity, metabolic pathways, gene regulatory cascades and protein interactions. We present a general approach for the representation and analysis of networks of variable type, size and complexity. The application is based on the original BioLayout program (C-language implementation of the Fruchterman-Rheingold layout algorithm), entirely re-written in Java to guarantee portability across platforms. BioLayout(Java) provides broader functionality, various analysis techniques, extensions for better visualisation and a new user interface. Examples of analysis of biological networks using BioLayout(Java) are presented.
Goldovsky
Leon
L
Computational Genomics Group, European Bioinformatics Institute, EMBL Cambridge Outstation, Cambridge, UK.
Cases
Ildefonso
I
Enright
Anton J
AJ
Ouzounis
Christos A
CA
D003196:Computer Graphics; D005786:Gene Expression Regulation / Q000502:physiology*; D011381:Programming Languages; D020543:Proteome / Q000737:chemistry* / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D012984:Software; D013329:Structure-Activity Relationship; D014584:User-Computer Interface
D020543:Proteome