Myasthenia gravis and hypothyroidism in a dog with meningomyelitis.
A 12-year-old, spayed female miniature poodle was evaluated because of a 4-day history of paraparesis, dysuria, and tenesmus. Neurological assessment suggested peripheral nervous system dysfunction, predominantly pelvic limb weakness with a possible concurrent sixth lumbar (L(6)) to second sacral (S(2)) myelopathy. Further studies supported the diagnoses of myasthenia gravis, hypothyroidism, and meningomyelitis. To the authors' knowledge, this is the first reported case of concurrent myasthenia gravis and meningomyelitis in the dog. It was unclear whether the identified conditions evolved from a shared etiopathogenesis or were merely coincidental.
Department of Small Animal Medicine, College of Veterinary Medicine, Texas A&M University, College Station, Texas 77843, USA.
Jonathan M
JM
Levine
Robert L
RL
Bergman
Joan R
JR
Coates
G Diane
GD
Shelton
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D015897:Comorbidity; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000188:drug therapy / Q000453:epidemiology*; D004285:Dogs; D005260:Female; D007037:Hypothyroidism / Q000188:drug therapy / Q000453:epidemiology / Q000662:veterinary*; D008159:Lumbar Vertebrae; D008581:Meningitis / Q000188:drug therapy / Q000453:epidemiology / Q000662:veterinary*; D009157:Myasthenia Gravis / Q000188:drug therapy / Q000453:epidemiology / Q000662:veterinary*; D009187:Myelitis / Q000188:drug therapy / Q000453:epidemiology / Q000662:veterinary*; D011241:Prednisone / Q000627:therapeutic use; D013974:Thyroxine / Q000627:therapeutic use; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D013974:Thyroxine; D011241:Prednisone