Adenomatoid odontogenic tumour: a clinico-pathological analysis and melanin pigmentation study of 31 Nigerian cases.
OBJECTIVE
Clinicopathological analysis and melanin pigmentation occurrence in adenomatoid odontogenic tumour (AOT) diagnosed and managed at the Lagos University Teaching Hospital during a 29- year period.


METHODS
Records of 31 cases were reviewed and standard epidemiological data were obtained. Haematoxylin and eosin stained slides of the cases were retrieved and reevaluated for reconfirmation of diagnosis. Celloidinised paraffin sections of all cases were subjected to Fontana Masson stain and melanin bleach to assess presence of melanin pigment.


RESULTS
AOT is an uncommon type of odontogenic tumour that is commoner in younger age group (8-35 years) with site predilection for the anterior maxilla (64.5%). Occurrence of melanin pigment in AOT was very rare as there was positive melanin pigmentation in only one case in spite of the fact that the study was carried out in a predominantly Black population.


CONCLUSIONS
Pattern of occurrence of AOT observed in this Lagos series is similar to previous studies in the scientific literature. Melanin pigmentation is rarely demonstrated in AOT even in a predominantly Black population.
Department of Oral Pathology and Biology, School of Dental Sciences, College of Medicine, University of Lagos, Nigeria.
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D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002648:Child; D006801:Humans; D007573:Jaw Neoplasms / Q000453:epidemiology / Q000473:pathology*; D008543:Melanins; D009549:Nigeria; D009808:Odontogenic Tumors / Q000453:epidemiology / Q000473:pathology*; D012880:Skin Pigmentation
D008543:Melanins