Cytotoxic chemotherapy: new players, new tactics.
Veterinary clients often seek the same new and innovative cancer treatment options for their companion animals that they read about in the press or on the Internet. It is, therefore, necessary for the practitioner to have an understanding of the development of new and innovative cytotoxic drugs and delivery techniques. This article describes the drug development process and how a new product eventually finds its way into clinical use. Some of the newer drugs and delivery techniques applied to small animals are reviewed.
Vail
David M
DM
Animal Cancer Center, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523, USA.
Thamm
Douglas H
DH
D000820:Animal Diseases / Q000188:drug therapy*; D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D003603:Cytotoxins / Q000627:therapeutic use*; D018572:Disease-Free Survival; D004305:Dose-Response Relationship, Drug; D015507:Drugs, Investigational; D009369:Neoplasms / Q000188:drug therapy / Q000662:veterinary*; D012074:Remission Induction; D013045:Species Specificity; D016896:Treatment Outcome
D000970:Antineoplastic Agents; D003603:Cytotoxins; D015507:Drugs, Investigational