Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human.
We report the initial sequencing and comparative analysis of the Macaca mulatta transcriptome. Cloned sequences from 11 tissues, nine animals, and three species (M. mulatta, M. fascicularis, and M. nemestrina) were sampled, resulting in the generation of 48,642 sequence reads. These data represent an initial sampling of the putative rhesus orthologs for 6,216 human genes. Mean nucleotide diversity within M. mulatta and sequence divergence among M. fascicularis, M. nemestrina, and M. mulatta are also reported.
Magness
Charles L
CL
Illumigen Biosciences Inc, Suite 450, 2203 Airport Way South, Seattle, WA 98134, USA.
Fellin
P Campion
PC
Thomas
Matthew J
MJ
Korth
Marcus J
MJ
Agy
Michael B
MB
Proll
Sean C
SC
Fitzgibbon
Matthew
M
Scherer
Christina A
CA
Miner
Douglas G
DG
Katze
Michael G
MG
Iadonato
Shawn P
SP
D000818:Animals; D000465:Algorithms; D001483:Base Sequence; D003001:Cloning, Molecular; D030561:Databases, Nucleic Acid; D017931:DNA Primers; D018076:DNA, Complementary / Q000235:genetics; D019143:Evolution, Molecular; D015723:Gene Library; D014644:Genetic Variation; D008252:Macaca fascicularis / Q000235:genetics; D008253:Macaca mulatta; D008254:Macaca nemestrina / Q000235:genetics; D020411:Oligonucleotide Array Sequence Analysis; D012689:Sequence Homology, Nucleic Acid; D014158:Transcription, Genetic; D006801:Humans
D017931:DNA Primers; D018076:DNA, Complementary