Xanthone glycosides from Polygala tenuifolia and their conformational analyses.
Seven xanthone glycosides were isolated from the cortexes of Polygala tenuifolia, and their structures were identified as polygalaxanthones VIII-XI (1-4), sibiricoxanthone B (5), 7-O-methylmangiferin (6), and lancerin (7), on the basis of spectroscopic analyses. Compounds 1-4 are new xanthone glycosides, and compounds 4 and 5 exist as rotamers. To explain this phenomenon, conformational analyses were performed on compounds 4 and 5 and other compounds with similar skeletons that were isolated from P. tenuifolia.
Jiang
Yong
Y
School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, People's Republic of China.
Zhang
Wei
W
Tu
Pengfei
P
Xu
Xiaojie
X
D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification*; D008516:Medicine, Chinese Traditional; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D031801:Polygala / Q000737:chemistry*; D044004:Xanthones / Q000737:chemistry* / Q000302:isolation & purification*
D006027:Glycosides; D044004:Xanthones; C009689:xanthone