Transformation of carbonates into sulfones at the benzylic position via palladium-catalyzed benzylic substitution.
[reaction: see text] The nucleophilic substitution of benzylic carbonates with sodium arenesulfinates was catalyzed by the palladium complex generated in situ from [Pd(eta(3)-C(3)H(5))Cl](2) and DPEphos [bis(2-diphenylphosphinophenyl)ether]. The catalytic reaction proceeded in DMSO at 80 degrees C and gave a variety of benzylic sulfones in high yields.
Department of Chemistry, Graduate School of Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan. rkuwascc@mbox.nc.kyushu-u.ac.jp
Ryoichi
R
Kuwano
Yutaka
Y
Kondo
Tsuyoshi
T
Shirahama