The role of fibronectin in fibroblast migration during tissue repair.
Fibronectin is known to stimulate cell growth and migration, but research does not provide a complete picture of all the mechanisms involved. Further studies are needed before practitioners can apply in vitro results to in vivo environments.
Royal Surrey County Hospital, Guildford, UK. sbriggs@royalsurrey.nhs.uk
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D000925:Anticoagulants / Q000494:pharmacology; D019898:Autocrine Communication / Q000502:physiology; D001665:Binding Sites; D002448:Cell Adhesion / Q000502:physiology; D002465:Cell Movement / Q000187:drug effects / Q000502:physiology*; D003094:Collagen / Q000502:physiology; D005109:Extracellular Matrix / Q000502:physiology; D005337:Fibrin / Q000502:physiology; D005347:Fibroblasts / Q000187:drug effects / Q000502:physiology*; D005353:Fibronectins / Q000737:chemistry / Q000145:classification / Q000502:physiology* / Q000627:therapeutic use; D006493:Heparin / Q000494:pharmacology / Q000502:physiology; D006801:Humans; D016023:Integrins / Q000502:physiology; D019899:Paracrine Communication / Q000502:physiology; D014945:Wound Healing / Q000187:drug effects / Q000502:physiology*
D000925:Anticoagulants; D005353:Fibronectins; D016023:Integrins; D005337:Fibrin; D006493:Heparin; D003094:Collagen