Primate glaucoma models.
The monkey model of ocular hypertension (OHT) with its resultant optic neuropathy closely reflects the optic neurodegeneration associated with human glaucoma. Utilization of the experimental glaucoma model (ExpG) in non-human primates (NHP) has led to advances in the understanding of aqueous humor dynamics, glaucomatous changes in the visual pathways from photoreceptors to the visual cortex, and anterior and posterior ocular segment pharmacological effects.
Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53792-3220, USA.
Carol A
CA
Rasmussen
Paul L
PL
Kaufman
D000818:Animals; D004195:Disease Models, Animal; D005901:Glaucoma / Q000473:pathology*; D007429:Intraocular Pressure; D008251:Macaca; D009798:Ocular Hypertension / Q000473:pathology; D009898:Optic Disk / Q000473:pathology; D009901:Optic Nerve Diseases / Q000473:pathology