Efficient optical resolution of secondary alkyl alcohols by chiral supramolecular hosts.
A novel tunable multi-chiral supramolecular host system was developed from non-chiral dicarboxylic acid and (1R, 2R)-diphenylethylenediamine via chirality transfer, which enabled highly efficient optical resolution of secondary alkyl alcohols by simple crystallization of host compounds from alcohol solution.
JST ERATO-SORST Kuroda Chiromorphology Team, 4-7-6, Komaba, Meguro-ku, Tokyo 153-0041, Japan.
Yoshitane
Y
Imai
Tomohiro
T
Sato
Reiko
R
Kuroda
D000438:Alcohols / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003998:Dicarboxylic Acids / Q000737:chemistry; D005029:Ethylenediamines / Q000737:chemistry; D006860:Hydrogen Bonding; D046911:Macromolecular Substances / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D009904:Optical Rotation; D013237:Stereoisomerism
D000438:Alcohols; D003998:Dicarboxylic Acids; D005029:Ethylenediamines; D046911:Macromolecular Substances; C518332:diphenylethylenediamine