The therapeutic potential of plant-derived vaccines and antibodies.
The production of recombinant proteins in plants is reviewed with a particular focus on plant-derived vaccines and antibodies for human healthcare. Issues relating to foreign gene expression, such as protein yield, localisation and glycosylation are also considered. Emphasis is placed on reporting progress with preclinical and clinical evaluation of plant-derived vaccines and antibodies. An assessment is made of the likely future direction of research and development in this area.
Rodgers
P B
PB
Axis Genetics plc, Babraham, Cambridge, CB2 4AZ, UK. rodgersp@axisgenetics.co.uk
Hamilton
W D
WD
Adair
J R
JR