Free radical scavenging activity of Achillea alexandri-regis extracts.
The antioxidative potential of Achillea alexandri-regis has been studied by measuring the influence of herb extracts on hydroxyl and superoxide radicals' quantity in different in vitro systems. The ethyl acetate extract exhibited hydroxyl radical scavenging activity in all tested biological system (liver homogenate, hemolyzed blood, serum and postmitochondrial liver fraction), whereas butanol extract reduced hydroxyl radicals significantly only in the postmitochondrial liver fraction. Both extracts showed superoxide radical scavenging effect only in hemolyzed blood.
Department of Pharmacognosy, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, Belgrade 11221, Serbia and Montenegro. ktatjana@bitsyu.net
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Kundaković
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Mimica Dukić
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Kovacević
D031162:Achillea; D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000737:chemistry / Q000494:pharmacology*; D017665:Hydroxyl Radical / Q000737:chemistry; D015227:Lipid Peroxidation / Q000187:drug effects; D008930:Mitochondria, Liver / Q000187:drug effects; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats; D013481:Superoxides / Q000737:chemistry
D000975:Antioxidants; D016166:Free Radical Scavengers; D010936:Plant Extracts; D013481:Superoxides; D017665:Hydroxyl Radical