Comparison of in vitro fertilization outcome in women with and without sonographic evidence of polycystic ovarian morphology.
OBJECTIVE
This study compared the outcome of in vitro fertilization (IVF) treatment in women who had polycystic ovaries (PCO) seen on an ultrasound scan, but who had no clinical symptomatology associated with polycystic ovary syndrome, with that of women who had normal ovarian morphology on ultrasound examination.


METHODS
Outcome of IVF 39 women with PCO evidence by ultrasound compared with 102 women, who had normal ovarian morphology by ultrasound. All 141 women had normal early follicular phase serum follicle stimulating hormone (FSH) concentration, were less than 40 years of age and used the long protocol pituitary suppression with gonadotropin-releasing hormone agonist therapy.


RESULTS
On average, the women with PCO produced more follicles and oocytes than the women with normal ovaries, but the fertilization cleavage and pregnancy rates were similar.


CONCLUSIONS
Although the response to follicular stimulation in PCO women is better than that for women with normal ovaries, the outcome of pregnancy in vitro fertilization is similar.
Esmailzadeh
Seddigheh
S
Department of obstetrics and Gynecology, Faculty of Medicine, Babol University of Medical Sciences, Iran.
Faramarzi
Mahbobeh
M
Jorsarai
Gholamali
G
D000328:Adult; D000367:Age Factors; D001707:Biopsy, Needle; D016022:Case-Control Studies; D016001:Confidence Intervals; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D005640:Follicle Stimulating Hormone / Q000032:analysis / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D007247:Infertility, Female / Q000628:therapy*; D016017:Odds Ratio; D010053:Ovary / Q000473:pathology*; D010062:Ovulation Induction / Q000379:methods; D011085:Polycystic Ovary Syndrome / Q000000981:diagnostic imaging* / Q000473:pathology; D011247:Pregnancy; D018873:Pregnancy Rate; D011336:Probability; D012016:Reference Values; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D018608:Ultrasonography, Doppler
D005640:Follicle Stimulating Hormone