SCANMOT: searching for similar sequences using a simultaneous scan of multiple sequence motifs.
Establishment of similarities between proteins is very important for the study of the relationship between sequence, structure and function and for the analysis of evolutionary relationships. Motif-based search methods play a crucial role in establishing the connections between proteins that are particularly useful for distant relationships. This paper reports SCANMOT, a web-based server that searches for similarities between proteins by simultaneous matching of multiple motifs. SCANMOT searches for similar sequences in entire sequence databases using multiple conserved regions and utilizes inter-motif spacing as restraints. The SCANMOT server is available via http://www.ncbs.res.in/~faculty/mini/scanmot/scanmot.html.
Chakrabarti
Saikat
S
National Centre for Biological Sciences (NCBS), Bangalore 560065, India.
Anand
A Prem
AP
Bhardwaj
Nitin
N
Pugalenthi
Ganesan
G
Sowdhamini
R
R
D000465:Algorithms; D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D017124:Conserved Sequence; D030562:Databases, Protein; D019143:Evolution, Molecular; D020407:Internet; D016415:Sequence Alignment; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software