Nephrogenic diabetes insipidus presenting with developmental delay and intracranial calcification.
A one-year-boy presented with constipation, fever, failure to thrive and developmental delay from the neonatal period. Investigations revealed persistent hypernatremia and deranged renal functions. Diagnostic work-up was suggestive of nephrogenic diabetes insipidus (NDI). Computerized tomography of head revealed calcification in the frontal, thalamic and basal ganglia region. The rare association of NDI and intracranial calcification is discussed.
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Anurag
A
Bajpai
Madhulika
M
Kabra
Rohini
R
Thapliyal
Sheffali
S
Gulati
Veena
V
Kalra
D001927:Brain Diseases / Q000209:etiology*; D002114:Calcinosis / Q000209:etiology*; D002658:Developmental Disabilities / Q000209:etiology*; D018500:Diabetes Insipidus, Nephrogenic / Q000150:complications*; D006801:Humans; D007223:Infant; D008297:Male