Sleep disturbance and depression as barriers to adherence.
This study examined the relationships among subjective sleep disturbance, depressive symptoms, and adherence to medications among HIV-infected women. HIV-infected women (N = 173) were recruited through community AIDS service organizations throughout South Carolina. Participants completed the Pittsburgh Sleep Quality Index (PSQI), the Centers for Epidemiological Studies Depression Scale (CES-D), and a modified version of the Adults AIDS Clinical Trials Group Adherence Baseline Questionnaire. Women who reported greater sleep disturbance also reported a higher level of depressive symptoms and reported poor adherence to their medication regimen. Depression helped to explain the relationship between sleep quality and adherence. Results indicate that assessment and management of sleep disturbance and depressive symptoms in women with HIV disease is important to promote medication adherence.
Phillips
Kenneth D
KD
College of Nursing, University of South Carolina, Columbia, USA.
Moneyham
Linda
L
Murdaugh
Carolyn
C
Boyd
Mary R
MR
Tavakoli
Abbas
A
Jackson
Kirby
K
Vyavaharkar
Medha
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D023241:Antiretroviral Therapy, Highly Active; D003430:Cross-Sectional Studies; D003863:Depression / Q000150:complications / Q000523:psychology*; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy* / Q000523:psychology*; D006801:Humans; D008875:Middle Aged; D010349:Patient Compliance / Q000523:psychology*; D012893:Sleep Wake Disorders / Q000150:complications / Q000523:psychology*; D013022:South Carolina