Accelerated partial breast irradiation: the case for current use.
The treatment of early stage breast cancer is evolving from traditional breast conservation techniques, employing conventionally fractionated whole breast irradiation, to techniques in which partial breast irradiation is used in an accelerated fractionation scheme. A growing body of evidence exists, including favorable findings. Additional studies are under way that may ultimately prove equivalence. The logic behind this approach is reviewed, and the currently available data are presented to support the current use of carefully applied partial breast irradiation techniques in appropriately selected and informed patients.
Keisch
Martin E
ME
Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida, USA. mkeisch@salick.com
D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D002986:Clinical Trials as Topic; D019583:Dose Fractionation, Radiation; D005260:Female; D006801:Humans; D007258:Informed Consent; D015412:Mastectomy, Segmental; D009367:Neoplasm Staging; D018579:Patient Selection; D011832:Radiation Injuries / Q000517:prevention & control; D018714:Radiotherapy, Adjuvant