Validation of an IVRS version of the MADRS.
Interest in self-reported measures of depression in clinical trials has grown in recent years. This study compared the reliability and validity of the clinician-administered Montgomery-Asberg Depression Rating Scale (MADRS) to a computer-administered version administered over the telephone using Interactive Voice Response (IVR) technology. Sixty subjects were administered both the clinician- and computer-administered versions of the MADRS in a counter-balanced order. A subsample of 20 patients was reassessed 24h later by both methods. Mean score differences between IVR and clinician were not statistically significant (<1 point) and a high correlation was found between forms (r=.815, p<.001). Reliability measures (Cronbach's Alpha and 24-h test-retest) were comparable. Clinicians rated the severity of subjects' sadness and pessimistic thoughts lower than subjects self-report. The data obtained in this pilot study provide support for the equivalence between the clinician and IVR versions of the MADRS.
Healthcare Technology Systems, Inc., 7617 Mineral Point Road, Madison, WI 53717, USA.
James C
JC
Mundt
David J
DJ
Katzelnick
Sidney H
SH
Kennedy
Beata S
BS
Eisfeld
Beverley B
BB
Bouffard
John H
JH
Greist
D000328:Adult; D003201:Computers; D003863:Depression / Q000175:diagnosis*; D001330:Electronic Data Processing; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires; D014584:User-Computer Interface