Resistant hypertension.
Hypertension that remains above 140/90 mmHg despite the use of three antihypertensive drugs in a rational combination at full doses and including a diuretic is known as 'resistant'. The percentage of hypertensives whose condition is resistant varies in large part upon the setting: those seen in general practice show a prevalence of perhaps 5%; those seen by nephrologists, probably 50%. This paper reviews the major causes of resistant hypertension and provides specific recommendations for the evaluation and management of patients with this threatening condition.
Kaplan
Norman M
NM
Department of Internal Medicine, Division of Hypertension, The University of Texas, Southwestern Medical Center, Dallas, Texas 75390, USA. Norman.Kaplan@UTSouthwestern.edu
D000959:Antihypertensive Agents / Q000627:therapeutic use*; D004232:Diuretics / Q000627:therapeutic use*; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000453:epidemiology; D015995:Prevalence
D000959:Antihypertensive Agents; D004232:Diuretics