The F1Fo-ATP synthase of Mycobacterium smegmatis is essential for growth.
The F(1)F(o)-ATP synthase plays an important role in a number of vital cellular processes in plants, animals, and microorganisms. In this study, we constructed a DeltaatpD mutant of Mycobacterium smegmatis and demonstrated that atpD encoding the beta subunit of the F(1)F(o)-ATP synthase is an essential gene in M. smegmatis during growth on nonfermentable and fermentable carbon sources.
Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand.
Sieu L
SL
Tran
Gregory M
GM
Cook
D001483:Base Sequence; D017931:DNA Primers; D017353:Gene Deletion; D020102:Mycobacterium smegmatis / Q000201:enzymology* / Q000235:genetics / Q000254:growth & development; D010957:Plasmids / Q000235:genetics; D021122:Protein Subunits / Q000235:genetics; D006180:Proton-Translocating ATPases / Q000235:genetics* / Q000378:metabolism*
D017931:DNA Primers; D021122:Protein Subunits; D006180:Proton-Translocating ATPases