Resistant hypertension.
Hypertension that remains above 140/90 mmHg despite the use of three antihypertensive drugs in a rational combination at full doses and including a diuretic is known as 'resistant'. The percentage of hypertensives whose condition is resistant varies in large part upon the setting: those seen in general practice show a prevalence of perhaps 5%; those seen by nephrologists, probably 50%. This paper reviews the major causes of resistant hypertension and provides specific recommendations for the evaluation and management of patients with this threatening condition.
Department of Internal Medicine, Division of Hypertension, The University of Texas, Southwestern Medical Center, Dallas, Texas 75390, USA. Norman.Kaplan@UTSouthwestern.edu
Norman M
NM
Kaplan
D000959:Antihypertensive Agents / Q000627:therapeutic use*; D004232:Diuretics / Q000627:therapeutic use*; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000453:epidemiology; D015995:Prevalence
D000959:Antihypertensive Agents; D004232:Diuretics