Comparison of prognostic value of negative dobutamine stress echocardiography versus single-photon emission computed tomography after acute myocardial infarction.
We enrolled 196 patients who had myocardial infarction and no ischemia on dobutamine stress echocardiography (DSE) and/or single-photon emission computed tomography (SPECT). Negative studies were observed in 125 patients on DSE and in 159 on SPECT. Patients were followed for 43 +/- 14 months. Cardiac events occurred in 14% of patients who did not have ischemia on DSE and in 9% of patients who did not have ischemia on SPECT. Event-free survival rate was higher in the presence of negative findings on SPECT compared with DSE (p <0.05). The lack of residual myocardial ischemia on SPECT identifies patients at low risk of events, and a negative finding on stress SPECT is superior to a negative finding on DSE.
Department of Biomorphological and Functional Sciences, Institute of Biostructure and Bioimages, National Council of Research, Naples, Italy.
Wanda
W
Acampa
Letizia
L
Spinelli
Mario
M
Petretta
Marco
M
Salvatore
Alberto
A
Cuocolo
D000328:Adult; D000368:Aged; D025401:Echocardiography, Stress; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000473:pathology; D017202:Myocardial Ischemia; D011237:Predictive Value of Tests; D011379:Prognosis; D011446:Prospective Studies; D011859:Radiography; D012307:Risk Factors; D016019:Survival Analysis; D015899:Tomography, Emission-Computed, Single-Photon