Herpes simplex virus type 2 acute retinal necrosis 9 years after neonatal herpes.
Many cases of acute retinal necrosis caused by HSV-2 have been reported in children, teenagers, and young adults as a result of reactivation of congenital or neonatal infections, which may have been subclinical. Pediatricians should be aware of this entity and alert to recurrences that may be delayed by years.
Landry
Marie L
ML
Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Conneticut 06520-8035, USA. marie.landry@yale.edu
Mullangi
Praveen
P
Nee
Paul
P
Klein
Betty R
BR
D000212:Acyclovir / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D020803:Encephalitis, Herpes Simplex / Q000150:complications*; D005260:Female; D018258:Herpesvirus 2, Human / Q000502:physiology*; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D015882:Retinal Necrosis Syndrome, Acute / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology*; D000077483:Valacyclovir; D014633:Valine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014775:Virus Activation
D000998:Antiviral Agents; D014633:Valine; D000077483:Valacyclovir; D000212:Acyclovir