New highly nucleophilic and practically accessible chlorocarbenoids for carbonyl olefination.
[reaction: see text] Direct oxidative addition of CHCl3 to the Mg-TiCl4 bimetallic species resulted in the generation of a highly nucleophilic and practically convenient chloromethylenetitanium complex, which efficiently effected condensation even with enolizable or inert carbonyl compounds, such as sterically congested ketones, to provide vinyl chloride compounds.
Department of Chemistry, National Chung-Hsing University, Taichung 400, Taiwan, Republic of China.
Chia-Chung
CC
Tsai
Ching-Ting
CT
Chien
Yu-Cheng
YC
Chang
Huan-Chang
HC
Lin
Tu-Hsin
TH
Yan