Effect of leisure time exercise on high-density lipoprotein cholesterol, its subclasses, and size in Asian Indians.
Asian Indians have a greater prevalence and incidence of coronary artery disease than other ethnic groups, despite similar routine lipid profiles. High-density lipoprotein (HDL) cholesterol, particularly the large subclass, is predominantly associated with coronary artery disease protection. Exercise reduces coronary artery disease risk by improving HDL cholesterol levels. The effect of exercise on HDL cholesterol concentrations, subclasses, and size, measured by nuclear magnetic resonance spectroscopy, was assessed in 388 healthy Asian Indians. Exercise was associated with significantly greater concentrations of total HDL cholesterol, entirely due to significant increases in the cardioprotective large HDL subclass and larger HDL cholesterol particle sizes.
Division of Cardiology, Department of Medicine, Bronx-Lebanon Hospital Center, Albert Einstein College of Medicine, Bronx, New York, USA. nbhalodkar@yahoo.com
Narendra C
NC
Bhalodkar
Steve
S
Blum
Thakor
T
Rana
Ami
A
Bhalodkar
R
R
Kitchappa
Enas A
EA
Enas
D000328:Adult; D044466:Asian People; D008076:Cholesterol, HDL / Q000097:blood*; D003324:Coronary Artery Disease / Q000209:etiology / Q000517:prevention & control; D015444:Exercise; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D011998:Recreation; D012307:Risk Factors
D008076:Cholesterol, HDL