[Developing and testing a method of in silico identification and characterization of meiotic DNA].
A method of in silico search for specific repetitive DNA sequences related to the synaptonemal complex (meiDNA) in mammalian genomes was developed. A study of the distribution of these repeats over chromosomes revealed their scarcity on the Y chromosome and a decrease in recombination frequency in regions enriched in meiDNA. The results are discussed in context of the model of the looplike meiotic chromosome organization during the formation of the synaptonemal complex.
T M
TM
Grishaeva
S Ia
SIa
Dadashev
Iu F
IuF
Bogdanov
D004247:DNA / Q000235:genetics*; D008540:Meiosis / Q000235:genetics*; D011995:Recombination, Genetic; D012091:Repetitive Sequences, Nucleic Acid
D004247:DNA