Fatal splenic rupture caused by infiltration of adult T cell leukemia cells.
The spleen is an immunological organ commonly involved in both hematological and nonhematological diseases. Pathological rupture of the spleen has been described in a variety of diseases affecting the spleen. Infections have been cited in most cases involving splenic rupture, but are rare in hematological malignancies despite frequent involvement of the spleen. The present report describes a fatal case of splenic rupture caused by infiltration of adult T cell leukemia cells and reports the mechanism of splenic rupture. The importance of rapid diagnosis and surgery is emphasized.
Department of Hematology and Immunology, Kagoshima University Hospital, Kagoshima, Japan.
Kosei
K
Arimura
Naomichi
N
Arima
Toshimasa
T
Kukita
Hirosaka
H
Inoue
Akihiko
A
Arai
Kakushi
K
Matsushita
Shuuhei
S
Taguchi
Hiroki
H
Yoshida
Atsuo
A
Ozaki
Hideaki
H
Kawada
Masaki
M
Akimoto
Chuwa
C
Tei
D017809:Fatal Outcome; D005260:Female; D015368:Human T-lymphotropic virus 1 / Q000302:isolation & purification; D006801:Humans; D015458:Leukemia, T-Cell / Q000150:complications* / Q000188:drug therapy / Q000821:virology; D008875:Middle Aged; D013161:Splenic Rupture / Q000209:etiology* / Q000473:pathology