One-Block CYRCA: an automated procedure for identifying multiple-block alignments from single block queries.
One-Block CYRCA is an automated procedure for identifying multiple-block alignments from single block queries (http://bioinfo.weizmann.ac.il/blocks/OneCYRCA). It is based on the LAMA and CYRCA block-to-block alignment methods. The procedure identifies whether the query blocks can form new multiple-block alignments (block sets) with blocks from a database or join pre-existing database block sets. Using pre-computed LAMA block alignments and CYRCA sets from the Blocks database reduces the computation time. LAMA and CYRCA are highly sensitive and selective methods that can augment many other sequence analysis approaches.
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
Milana
M
Frenkel-Morgenstern
Alice
A
Singer
Hagit
H
Bronfeld
Shmuel
S
Pietrokovski
D000465:Algorithms; D030562:Databases, Protein; D020407:Internet; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software; D014584:User-Computer Interface