Sanguinarine activates polycyclic aromatic hydrocarbon associated metabolic pathways in human oral keratinocytes and tissues.
Dvorak
Zdenek
Z
Modriansky
Martin
M
Simanek
Vilim
V
Ulrichova
Jitka
J
Vicar
Jaroslav
J
Vrba
Jiri
J
Walterova
Daniela
D
D000470:Alkaloids / Q000493:pharmacokinetics / Q000633:toxicity*; D053119:Benzophenanthridines; D001711:Biotransformation; D002470:Cell Survival / Q000187:drug effects; D019363:Cytochrome P-450 CYP1A1 / Q000096:biosynthesis* / Q000235:genetics; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects; D006801:Humans; D007546:Isoquinolines; D015603:Keratinocytes / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology; D009061:Mouth Mucosa / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology; D009067:Mouthwashes / Q000493:pharmacokinetics / Q000633:toxicity*; D018336:Receptors, Aryl Hydrocarbon / Q000096:biosynthesis* / Q000235:genetics
D000470:Alkaloids; D053119:Benzophenanthridines; D007546:Isoquinolines; D009067:Mouthwashes; D018336:Receptors, Aryl Hydrocarbon; C005705:sanguinarine; D019363:Cytochrome P-450 CYP1A1