[A protocol of automatic alignment of genome sequences using the program OWEN].
A protocol of automatic hierarchical alignment of long DNA sequences using the program OWEN is described. The protocol is based on the command line regime of the program OWEN. The protocol makes it possible to align a large number of pairs of moderately similar sequences automatically. We used this protocol to align 8623 orthologous pairs of intergenic regions in human and murine genomes.
Ogurtsov
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AIu
D000818:Animals; D019295:Computational Biology; D015894:Genome, Human; D006801:Humans; D051379:Mice; D016415:Sequence Alignment / Q000379:methods; D017422:Sequence Analysis, DNA / Q000379:methods; D012984:Software