Sniffing Out NMDA Receptors in the Olfactory Cortex.
Selective olfactory learning is essential for survival in most newborn mammals. Findings by Franks and Isaacson in this issue of Neuron suggest that early olfactory learning might be selective, in part because olfactory experience downregulates NMDA receptors at primary inputs to the olfactory cortex.
Philpot
Benjamin D
BD
Department of Cell and Molecular Physiology, UNC Neuroscience Center, University of North Carolina, Chapel Hill, NC 27599, USA.
D000818:Animals; D000831:Animals, Newborn / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn; D007858:Learning / Q000502:physiology; D009833:Olfactory Pathways / Q000502:physiology*; D018091:Receptors, AMPA / Q000502:physiology; D016194:Receptors, N-Methyl-D-Aspartate / Q000187:drug effects / Q000502:physiology*; D012903:Smell / Q000502:physiology*; D013569:Synapses / Q000502:physiology
D018091:Receptors, AMPA; D016194:Receptors, N-Methyl-D-Aspartate