[One man of five aged 50 years and over referred to a urologist is diagnosed with cancer. PSA analysis is important for correct prioritization of the referrals].
In 20% of the men 50 years of age and older referred to a urological specialist clinic, a cancer, mostly a prostate cancer, was diagnosed. No symptom mentioned in the referral form was correlated to the diagnosis of a cancer. S-PSA density did not have a better predictive value than S-PSA alone. S-PSA 3.0 microg/L as a borderline for prostate biopsy or not had a 99.5% negative predictive value and only a slightly lower specificity then 4.0 microg/L. In clinical practice, for patients where curative treatment is feasible, S-PSA 3.0 microg/L appears to be a more appropriate borderline for prostate biopsy than 4 microg/L.
Boman
Hans
H
Urologkliniken och FoU-centrum, Kärnsjukhuset, Skövde, Sweden. hans.boman@vgregion.se
Hedelin
Hans
H
D014408:Biomarkers, Tumor / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood*; D012017:Referral and Consultation; D012680:Sensitivity and Specificity; D014572:Urology
D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen