Effects of hyperglycemia on neurologic outcome in stroke patients.
Hyperglycemia in acute stroke patients increases cerebral infarct size and worsens neurologic outcome with and without preexisting diabetes mellitus. Hyperglycemia results from metabolic alterations in glucose metabolism, and is most common in patients with acute illness such as stroke. Strict control of hyperglycemia with intensive insulin therapy has been shown to dramatically decrease hospital morbidity and mortality, inpatient stays, hospital costs, and, most importantly, neurologic injury. Insulin treatment protocols developed and implemented by multidisciplinary teams allow for rapid and effective control of hyperglycemia. Nurses who know about hyperglycemia's often-neglected and detrimental effects can play a vital role in influencing outcomes in stroke patients.
Paolino
Alison S
AS
Emory University Hospital, Atlanta, GA, USA. alison_paolino@emoryhealthcare.org
Garner
Krista M
KM
D001786:Blood Glucose / Q000378:metabolism; D002544:Cerebral Infarction / Q000209:etiology; D002985:Clinical Protocols; D003422:Critical Care / Q000379:methods; D016638:Critical Illness; D048909:Diabetes Complications / Q000150:complications; D006301:Health Services Needs and Demand; D017721:Hospital Costs / Q000706:statistics & numerical data; D017052:Hospital Mortality; D006801:Humans; D006943:Hyperglycemia / Q000209:etiology* / Q000378:metabolism / Q000517:prevention & control*; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007262:Infusions, Intravenous; D007328:Insulin / Q000627:therapeutic use; D007333:Insulin Resistance; D007902:Length of Stay / Q000706:statistics & numerical data; D009017:Morbidity; D024802:Nurse's Role; D010348:Patient Care Team / Q000458:organization & administration; D011379:Prognosis; D012307:Risk Factors; D020521:Stroke / Q000150:complications* / Q000453:epidemiology; D016896:Treatment Outcome
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin