A histological study of articular cartilage after rotational acetabular osteotomy for hip dysplasia.
Acetabular dysplasia was produced in 24 immature white rabbits. A rotational acetabular osteotomy was then carried out and radiological and histological studies of the articular cartilage were made. In the hips which did not undergo osteotomy, radiographs at 26 weeks showed that residual subluxation remained and arthritic changes such as narrowing of the joint space or dislocation were still seen. However, in the operated group there was a remarkable increase in cover, but arthritic changes were not observed. After 24 weeks, the Mankin grading score in the operated group was significantly lower than that in the non-operated group. The latter hips showed an irregular surface of the cartilage, exfoliation and proliferation of synovial tissue. In those undergoing osteotomy, primary cloning of chondrocytes or hypercellularity was seen and at 24 weeks after operation and metaplasia of the cartilage in the fibrous tissue was observed in the boundary between the medial area of the acetabulum and the acetabular fossa.
Shimogaki
K
K
Department of Orthopaedic Surgery, Miyoshi Central Hospital, 531 Higashisakeya, Miyoshi, Hiroshima 728-8502, Japan. koichishimogaki@yahoo.co.jp
Yasunaga
Y
Y
Ochi
M
M
D000077:Acetabulum / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D000818:Animals; D002358:Cartilage, Articular / Q000000981:diagnostic imaging / Q000473:pathology*; D005270:Femur Head / Q000473:pathology; D006617:Hip Dislocation / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D007150:Immunohistochemistry / Q000379:methods; D010027:Osteotomy / Q000379:methods*; D011817:Rabbits; D011859:Radiography; D012399:Rotation