Transfusion associated GVHD.
Transfusion-associated graft-versus-host disease (TA-GVHD) is an under-diagnosed condition in clinical practice. It can occur in immunocompromised as well as immunocompetent hosts and may follow allogeneic bone marrow transplant or transfusion from a related donor. The clinical course is stormy with a high mortality rate. Avoiding the use of blood transfusions from related donors and irradiation of blood products can prevent graft versus host disease. A case of graft versus host disease following related donor transfusion is presented here.
Sohi
Inderpreet
I
Department of Pediatrics, Christian Medical College and Hospital, Ludhiana, Punjab, India. n_kakkar@satyam.net.in
Jacob
Sunitha
S
D006086:Graft vs Host Disease / Q000209:etiology*; D006801:Humans; D007223:Infant; D008297:Male; D065227:Transfusion Reaction