Aortic valve replacement for a patient with glucose-6-phosphate dehydrogenase deficiency and autoimmune hemolytic anemia.
Autoimmune hemolytic anemia and deficiency of glucose-6-phosphate deyhdrogenase (G6PD) result in severe hemolysis with different mechanisms. In patients with both pathologies, the effects of cardiopulmonary bypass on red blood cells and thrombocytes demand special care before and after open heart surgery. We evaluated the preoperative management and postoperative care of a patient with severe aortic insufficiency associated with G6PD deficiency and autoimmune hemolytic anemia who underwent aortic valve replacement.
Tas
Serpil
S
Cardiovascular Surgery Department of Kosuyolu Heart and Research Hospital, Istanbul, Turkey. serpil@celtas.com.tr
Donmez
Arzu Antal
AA
Kirali
Kaan
K
Alp
Mete H
MH
Yakut
Cevat
C
D000293:Adolescent; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications*; D001021:Aortic Valve / Q000382:microbiology / Q000601:surgery*; D004697:Endocarditis, Bacterial / Q000150:complications / Q000601:surgery*; D005954:Glucosephosphate Dehydrogenase / Q000032:analysis; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications*; D019918:Heart Valve Prosthesis Implantation; D006461:Hemolysis; D006801:Humans; D008297:Male; D011182:Postoperative Care; D011300:Preoperative Care
D005954:Glucosephosphate Dehydrogenase