Autosomal dominant osteopetrosis and maxillomandibular osteomyelitis.
Osteopetroses represent a heterogeneous group of rare, hereditary bony dysplasias. They range from a devastating neurometabolic disease (including severe malignant infantile osteopetrosis) to 2 more benign conditions principally affecting adults: autosomal dominant osteopetrosis (ADO) type I and type II. The present study describes the maxillofacial manifestations associated with the 2 subgroups of ADO. In this paper, we present the oldest patient described in the literature with ADO type I (76 years old). We also document the first ADO type II patient described in the literature with synchronic osteomyelitis of the mandible and the maxilla.
Department of Oral and Maxillofacial Surgery, University of Oviedo, Central Hospital of Asturias, Spain. junquera@sci.cpd.uniovi.es
Luis
L
Junquera
Cristian
C
Rodríguez-Recio
Pedro
P
Villarreal
Luis
L
García-Consuegra
D000368:Aged; D025063:Chromosome Disorders / Q000150:complications / Q000235:genetics* / Q000473:pathology*; D005260:Female; D006801:Humans; D007571:Jaw Diseases / Q000000981:diagnostic imaging / Q000209:etiology; D008297:Male; D019767:Maxillofacial Abnormalities / Q000000981:diagnostic imaging / Q000209:etiology*; D008875:Middle Aged; D010019:Osteomyelitis / Q000000981:diagnostic imaging / Q000209:etiology; D010022:Osteopetrosis / Q000150:complications / Q000235:genetics* / Q000473:pathology*; D014057:Tomography, X-Ray Computed