The F1Fo-ATP synthase of Mycobacterium smegmatis is essential for growth.
The F(1)F(o)-ATP synthase plays an important role in a number of vital cellular processes in plants, animals, and microorganisms. In this study, we constructed a DeltaatpD mutant of Mycobacterium smegmatis and demonstrated that atpD encoding the beta subunit of the F(1)F(o)-ATP synthase is an essential gene in M. smegmatis during growth on nonfermentable and fermentable carbon sources.
Tran
Sieu L
SL
Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand.
Cook
Gregory M
GM
D001483:Base Sequence; D017931:DNA Primers; D017353:Gene Deletion; D020102:Mycobacterium smegmatis / Q000201:enzymology* / Q000235:genetics / Q000254:growth & development; D010957:Plasmids / Q000235:genetics; D021122:Protein Subunits / Q000235:genetics; D006180:Proton-Translocating ATPases / Q000235:genetics* / Q000378:metabolism*
D017931:DNA Primers; D021122:Protein Subunits; D006180:Proton-Translocating ATPases