A clinician's guide to the appropriate and accurate use of antibiotics: the Council for Appropriate and Rational Antibiotic Therapy (CARAT) criteria.
In response to the overuse and misuse of antibiotics, leading to increasing bacterial resistance and decreasing development of new antibiotics, the Council for Appropriate and Rational Antibiotic Therapy (CARAT) has developed criteria to guide appropriate and accurate antibiotic selection. The criteria, which are aimed at optimizing antibiotic therapy, include evidence-based results, therapeutic benefits, safety, optimal drug for the optimal duration, and cost-effectiveness.
Department of Infectious Diseases, Indiana University School of Medicine, Indiana University, Indianapolis, Indiana, USA.
Thomas G
TG
Slama
Alpesh
A
Amin
Stephen A
SA
Brunton
Thomas M
TM
File
Gary
G
Milkovich
Keith A
KA
Rodvold
Daniel F
DF
Sahm
Joseph
J
Varon
David
D
Weiland
D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000191:economics / Q000493:pharmacokinetics; D001424:Bacterial Infections / Q000188:drug therapy*; D003362:Cost-Benefit Analysis; D004363:Drug Utilization / Q000592:standards*; D006801:Humans; D018579:Patient Selection
D000900:Anti-Bacterial Agents