Nickel-catalyzed addition of P(O)-H bonds to propargyl alcohols: one-pot generation of phosphinoyl 1,3-butadienes.
[reaction: see text] Diphenylphosphine oxide and related P(O)H compounds react with propargyl alcohols at room temperature in the presence of a catalytic amount of Ni(0) complex and Ph(2)P(O)OH to produce high yields of phosphinoyl 1,3-dienes though an efficient in situ dehydration process.
National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan. libiao-han@aist.go.jp
Li-Biao
LB
Han
Yutaka
Y
Ono
Hideaki
H
Yazawa