First insight into the symmetry and flexibility of membrane efflux pump P-glycoprotein by novel bifunctional modulators.
Fachbereich Pharmazie, Institut für Pharmazeutische Chemie, Martin-Luther Universität, Wolfgang-Langenbeck-Strasse 4, 06120 Halle, Germany.
Jörg
J
Wollmann
Martin
M
Richter
Jósef
J
Molnár
Andreas
A
Hilgeroth
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism; D062365:Aminobenzoates / Q000494:pharmacology*; D000818:Animals; D045744:Cell Line, Tumor; D003432:Cross-Linking Reagents / Q000737:chemistry*; D019281:Dimerization; D004305:Dose-Response Relationship, Drug; D017320:HIV Protease Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D026901:Membrane Transport Proteins / Q000378:metabolism*; D051379:Mice
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D062365:Aminobenzoates; D003432:Cross-Linking Reagents; D017320:HIV Protease Inhibitors; D026901:Membrane Transport Proteins