[Can vulvar carcinoma be a danger in the 21st century?].
Vulvar carcinoma accounts for 3-5% of all genital cancers. The most common histology of vulvar cancer is squamous cell carcinoma. It has been suggested that vulvar cancer exists as two separate diseases--HPV-positive, occurring in young women, and p53-positive, that occurs in older women. As extensive surgery resection is gold standard of treatment, it is important to play attention for all symptoms, suggesting the beginning of disease. Understanding of the anatomy and the mechanism of lymphatic spread have made modifications in surgical technique possible, allowing less radical excisions.
Ciszko
Beata
B
Klinika Ginekologii II Katedry Ginekologii i Połoznictwa Akademii Medycznej we Wrocławiu. bciszko@wp.pl
Gabryś
Marian S
MS
Pochwałowski
Marek
M
D002294:Carcinoma, Squamous Cell / Q000737:chemistry / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery / Q000821:virology; D003937:Diagnosis, Differential; D005260:Female; D049674:History, 21st Century; D006801:Humans; D027383:Papillomaviridae / Q000302:isolation & purification; D016159:Tumor Suppressor Protein p53 / Q000032:analysis; D014846:Vulvar Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery / Q000821:virology
D016159:Tumor Suppressor Protein p53