[Demodecidosis in a patient infected by HIV: successful treatment with ivermectin].
BACKGROUND
Demodex is a saprophyte parasite in mammals. In Man, it is associated with differing clinical profiles (rosacea-like dermatitis, folliculitis and blepharitis). We report a case of demodecidosis in an HIV-infected patient that was successfully treated with ivermectin.


METHODS
A man from Laos, infected by HIV and treated for glandular tuberculosis, presented with a prurigenous eruption on the face and the pre-sternal and interscapular areas. Direct examination of scraped product and histopathological examinations confirmed the diagnosis of demodecidosis. Clinical cure was obtained after 2 single cures of ivermectin a one month's distance.


CONCLUSIONS
The features of demodecidosis are often similar to those of rosacea. In immunodeficient patients, the semiology remains the same but the eruption is more abundant. During HIV-infection, demodecidosis occurs at the AIDS stage or with a CD4 count lower than 200/mm3. Many anti-dust mite molecules are used to treat the disease but frequently lead to irritation. Administration of a single cure of ivermectin, repeated if necessary, appears to be an interesting alternative to contact anti-dust mite agents.
Service de Dermatologie, Institut Guyanais de Dermatologie Tropicale, Hôpital de Cayenne, Guyane Française.
E
E
Clyti
K
K
Sayavong
K
K
Chanthavisouk
D000328:Adult; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007306:Insecticides / Q000627:therapeutic use*; D007559:Ivermectin / Q000627:therapeutic use*; D008297:Male; D008924:Mite Infestations / Q000188:drug therapy* / Q000209:etiology / Q000821:virology; D016896:Treatment Outcome
D007306:Insecticides; D007559:Ivermectin