In vitro antimicrobial susceptibility testing of Helicobacter felis, H. bizzozeronii, and H. salomonis.
The susceptibilities of Helicobacter felis (15 strains), H. bizzozeronii (7 strains), and H. salomonis (3 strains) to 10 antimicrobial agents were investigated by determination of the MIC using the agar dilution method. No consistent differences were noticed between the different Helicobacter species, which were all highly susceptible to ampicillin, clarithromycin, tetracycline, tylosin, enrofloxacin, gentamicin, and neomycin, as demonstrated by low MICs. Higher MICs were obtained for lincomycin (up to 8 microg/ml) and spectinomycin (up to 4 microg/ml). Two H. felis strains showed a MIC of 16 microg/ml for metronidazole, suggesting acquired resistance to this antimicrobial agent.
Van den Bulck
K
K
Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium. kathleen.vandenbulck@UGent.be
Decostere
A
A
Gruntar
I
I
Baele
M
M
Krt
B
B
Ducatelle
R
R
Haesebrouck
F
F
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002371:Cat Diseases / Q000382:microbiology*; D002415:Cats; D004283:Dog Diseases / Q000382:microbiology*; D004285:Dogs; D024881:Drug Resistance, Bacterial; D016998:Helicobacter / Q000145:classification / Q000187:drug effects*; D016481:Helicobacter Infections / Q000382:microbiology*; D044922:Helicobacter felis / Q000187:drug effects*; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests / Q000379:methods / Q000592:standards
D000900:Anti-Bacterial Agents; D008795:Metronidazole