Speech-language characteristics of children with Sotos syndrome.
The purpose of this research study was to evaluate the communication of individuals with Sotos syndrome in order to better characterize common speech and language patterns. Sixteen children with Sotos syndrome received an in-depth communication assessment using standardized procedures. Assessments of speech skills, language skills, voice, fluency, and social-pragmatic interactions were completed. Results of the evaluations indicated that individuals with Sotos syndrome are prone to: (a) language impairments (particularly expressive), (b) speech sound production impairments, (c) voice impairments, (d) dysfluencies (stuttering), and (e) average social-behavioral pragmatic interaction characteristics.
Ball
Laura J
LJ
Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, Nebraska 68198-5450, USA. lball@unmc.edu
Sullivan
Marsha D
MD
Dulany
Susan
S
Stading
Korey
K
Schaefer
G Bradley
GB
D000015:Abnormalities, Multiple / Q000235:genetics / Q000473:pathology*; D001184:Articulation Disorders / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000473:pathology*; D006130:Growth Disorders / Q000473:pathology*; D000076983:Histone Methyltransferases; D011495:Histone-Lysine N-Methyltransferase; D006801:Humans; D007223:Infant; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics; D007806:Language Disorders / Q000473:pathology*; D007807:Language Tests; D009154:Mutation; D009687:Nuclear Proteins / Q000235:genetics; D013064:Speech Disorders / Q000473:pathology*; D013577:Syndrome
D047908:Intracellular Signaling Peptides and Proteins; D009687:Nuclear Proteins; D000076983:Histone Methyltransferases; D011495:Histone-Lysine N-Methyltransferase; C113272:NSD1 protein, human