Successful mitral valve replacement in a patient with Ehlers-Danlos syndrome type VI.
A 40-year-old patient with Ehlers-Danlos syndrome type VI (ocular type) had mitral regurgitation due to mitral valve prolapse. Because the patient's tissue was fragile, we replaced the mitral valve with a reinforced prosthetic valve to prevent paravalvular leakage. The excised mitral leaflet showed significant myxomatous change and decrease in collagen fibers. We believe this is the first report of cardiac surgery in a patient with Ehlers-Danlos syndrome type VI.
Takano
Hiroshi
H
Division of Cardiovascular Surgery, Department of Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. htakano-cvs@umin.ac.jp
Miyamoto
Yuji
Y
Sawa
Yoshiki
Y
Fukushima
Norihide
N
Matsumiya
Goro
G
Fujita
Tomoyuki
T
Matsuda
Hikaru
H
D000328:Adult; D004535:Ehlers-Danlos Syndrome / Q000150:complications*; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000601:surgery*; D016896:Treatment Outcome