Alzheimer pathology associated with POLG1 mutation, multiple mtDNA deletions, and APOE4/4: premature ageing or just coincidence?
Atle
A
Melberg
Inger
I
Nennesmo
Ali-Reza
AR
Moslemi
Gittan
G
Kollberg
Petri
P
Luoma
Anu
A
Suomalainen
Elisabeth
E
Holme
Anders
A
Oldfors
D017668:Age of Onset; D000375:Aging / Q000235:genetics; D019588:Aging, Premature / Q000235:genetics* / Q000378:metabolism / Q000503:physiopathology; D000544:Alzheimer Disease / Q000235:genetics* / Q000378:metabolism / Q000503:physiopathology; D053327:Apolipoprotein E4 / Q000235:genetics*; D004252:DNA Mutational Analysis; D000074002:DNA Polymerase gamma; D004272:DNA, Mitochondrial / Q000235:genetics*; D004259:DNA-Directed DNA Polymerase / Q000235:genetics*; D018450:Disease Progression; D005260:Female; D017353:Gene Deletion; D005819:Genetic Markers / Q000235:genetics; D020022:Genetic Predisposition to Disease / Q000235:genetics; D005820:Genetic Testing; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D017240:Mitochondrial Myopathies / Q000235:genetics / Q000378:metabolism / Q000503:physiopathology; D009154:Mutation / Q000235:genetics; D017246:Ophthalmoplegia, Chronic Progressive External / Q000235:genetics* / Q000378:metabolism / Q000503:physiopathology; D035781:Siblings; D013548:Sweden
D053327:Apolipoprotein E4; D004272:DNA, Mitochondrial; D005819:Genetic Markers; D000074002:DNA Polymerase gamma; D004259:DNA-Directed DNA Polymerase; C413027:POLG protein, human