Lipase-catalyzed glucose fatty acid ester synthesis in ionic liquids.
[reaction: see text] Glucose fatty acid ester synthesis with poly(ethylene glycol)-modified Candida antarctica lipase B (CAL-B) was performed in pure 1-butyl-3-methyl imidazolium tetrafluoroborate [BMIM][BF(4)] (30% conversion) and in pure 1-butyl-3-methyl imidazolium hexafluorophosphate [BMIM][PF(6)] (35% conversion). In a solvent system composed of ionic liquid and 40% t-BuOH conversions up to 90% and isolated yields of up to 89% were achieved using fatty acid vinyl esters as acyl donors and commercial CAL-B.
Ganske
Franka
F
Department of Technical Chemistry and Biotechnology, Institute of Chemistry and Biochemistry, Greifswald University, Germany.
Bornscheuer
Uwe T
UT
D002384:Catalysis; D004951:Esterification; D004952:Esters; D005227:Fatty Acids / Q000138:chemical synthesis*; D005656:Fungal Proteins; D005947:Glucose / Q000031:analogs & derivatives* / Q000138:chemical synthesis*; D008049:Lipase / Q000378:metabolism*
D004952:Esters; D005227:Fatty Acids; D005656:Fungal Proteins; D008049:Lipase; C431349:lipase B, Candida antarctica; D005947:Glucose