Patient with double bence jones proteinuria after hematopoietic cell transplantation.
About two thirds of patients with multiple myeloma and M-component in serum also have light chains in urine. However, the simultaneous presence of 2 Bence Jones proteins of different immunologic types in the same patient is rare. We describe the case of a 58-year-old woman with multiple myeloma, having 2 monoclonal light chains of both types (kappa and lambda) and an immunoglobulin G-lambda monoclonal protein in urine. The quantitative determination of light chains in urine was carried out using nephelometry, and Bence Jones proteinuria was confirmed by agarose gel immunofixation. To the best of our knowledge, this is the first reported case of double Bence Jones proteinuria after hematopoietic cell transplantation.
Méndez-Arredondo
Jose-Antonio
JA
Department of Clinical Analysis, Complejo Hospitalario Universitario Juan Canalejo, Coruña, Spain.
Rodríguez-López
Inés
I
González-Morales
Isabel
I
Debén-Ariznavarreta
Guillermo
G
Fernández-Rodríguez
Fernando
F
Sánchez-Mozo
Pilar
P
D001536:Bence Jones Protein / Q000652:urine*; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D011507:Proteinuria / Q000175:diagnosis*
D001536:Bence Jones Protein