[Monogenic diabetes: a useful dimension for diabetology practice].
The number of identified monogenic diabetes progressively increases with time even if these forms of diabetes represent less than 5% of the cases. Every monogenic diabetes is characterized by an impairment of Beta cell at various levels. They are good models of diabetes-prone mechanisms. Diabetologists should recognize these forms because the management of the patients could be modified as a function of the genetic anomaly, in terms of either choice of hypoglycaemic agents, prognostic, management of associated manifestations or genetic counselling.
Service de Nutrition, Maladies métaboliques et Endocrinologie, Hôpital de la Timone, CHU de Marseille, rue Saint-Pierre, 13005 Marseille.
R
R
Valéro
S
S
Béliard
V
V
Paquis-Fluckinger
B
B
Vialettes
D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy / Q000235:genetics*; D005817:Genetic Counseling; D020022:Genetic Predisposition to Disease; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007515:Islets of Langerhans / Q000503:physiopathology; D008957:Models, Genetic; D014929:Wolfram Syndrome / Q000235:genetics
D007004:Hypoglycemic Agents