[Exposing the rabbit cerebellopontine angle through post-sigmoid sinus approach and recording the direct compound action potential of the auditory nerve].
OBJECTIVE
To study the way of exposing the rabbit cerebellopontine angle through post-sigmoid sinus approach and recording the direct compound action potential of the auditory nerve, and to investigate the stability of DCAP N1 wave latency.


METHODS
Fifteen New Zealand rabbits which had normal Preyer's auricle reflex were selected. Each one was studied in the left ear. After anaesthetized,the cerebellopontine angle of rabbits were exposed through post-sigmoid sinus approach under aseptic status,then the needle-shaped pole were inserted into the facial-acoustic nerve complex. The DCAP was recorded at the immediateness, 2 h and 5 h after the insertino sequentially. At last, DCAP N1 wave latencies of 15 rabbits were statisticed and analyzed using paired-samples t-test.


RESULTS
To the 15 sides, the distinct curves with well differentiated waves were induced in the all three times. No significant difference in any N1 wave latency had been found among the 3 times.


CONCLUSIONS
The rabbit cerebellopontine angle could be exposed and the direct compound action potential of the auditory nerve could be recorded successfully by the way studied in this experiment. In normal state, the individual value of DCAP N1 wave latency is stable. During the process of surgery in which the cerebellopontine angle has been exposed, the DCAP N1 wave latency is a practical index for monitoring of hearing impairment.
Zhu
Ming
M
Department of Otolaryngology-Head and Neck Surgery, Xinhua Hospital of the Second Medical University, Shanghai, 200092, China. zhuming_pearl@hotmail.com
Wu
Hao
H
Li
Zhaoji
Z
Chen
Xiangping
X
Cao
Rongping
R
Shen
Min
M
Zhu
Chunsheng
C
Zhou
Jingfeng
J
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D001309:Auditory Threshold; D002530:Cerebellopontine Angle / Q000601:surgery*; D003056:Cochlear Nerve / Q000502:physiology*; D005260:Female; D008297:Male; D011817:Rabbits