Colonic microbiota signatures across five northern European countries.
The composition of the colonic microbiota of 91 northern Europeans was characterized by fluorescent in situ hybridization using 18 phylogenetic probes. On average 75% of the bacteria were identified, and large interindividual variations were observed. Clostridium coccoides and Clostridium leptum were the dominant groups (28.0% and 25.2%), followed by the Bacteroides (8.5%). According to principal component analysis, no significant grouping with respect to geographic origin, age, or gender was observed.
Lay
Christophe
C
Unité d'Ecologie et de Physiologie du Système Digestif, Institut National de la Recherche Agronomique, 78352 Jouy-en-Josas Cedex, France.
Rigottier-Gois
Lionel
L
Holmstrøm
Kim
K
Rajilic
Mirjana
M
Vaughan
Elaine E
EE
de Vos
Willem M
WM
Collins
Matthew D
MD
Thiel
Ralph
R
Namsolleck
Pawel
P
Blaut
Michaël
M
Doré
Joël
J
D000293:Adolescent; D000328:Adult; D001439:Bacteroides / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D002648:Child; D003013:Clostridium / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D003106:Colon / Q000382:microbiology*; D005060:Europe; D005434:Flow Cytometry; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008875:Middle Aged; D015999:Multivariate Analysis