Normative data of bone Mineral Density in healthy population of Tehran, Iran: a cross sectional study.
BACKGROUND
Osteoporosis is a major problem and is a hidden epidemic disease in the world. Early diagnosis by measurement of Bone Mineral Density (BMD) and treatment can prevent and reduce disease complications, especially fractures. As there is no comprehensive study in Iran, this study designed to assess BMD discrepancy in 20-69 yr Tehran population as well as prevalence of osteoporosis and osteopenia.


METHODS
553 people (34% men, 66%women) from 50 Blocks in Tehran randomly selected. The assessment of BMD in spine and femur region performed through DXA method. All subjects clinically examined and their BMIs determined.


RESULTS
The average spinal BMD score in men were more than in women. The peak bone mass of spine bone both in men and women occurred during 20-29 yr and reduction began from the age of 40. At the age of 60 to 69, loose of bone density was 19.6% in lumbar spine and 18.5% in femur of women and also 7.9% in lumbar spine and 14.6% in femur of men. Prevalence of osteoporosis in this age group in lumbar spine and femur was 32.4% and 5.9% in women and 9.4% and 3.1% in men respectively.


CONCLUSIONS
In all age groups, peak bone mass was lower than European or American population, whereas the rate of bone loss was as much as the some population and actually this process justifies the prevalence of osteoporosis and osteopenia in Tehran population.
Endocrinology & Metabolism Research Center, Tehran University of Medical Sciences, Fifth floor, Dr, Shariati Hospital, North Kargar Ave, Tehran, 14114, Iran. emrc@sina.tums.ac.ir
Bagher
B
Larijani
Arash
A
Hossein-Nezhad
Alireza
A
Mojtahedi
Mohammad
M
Pajouhi
Mohammad H
MH
Bastanhagh
Akbar
A
Soltani
Seyed-Zahra
SZ
Mirfezi
Roya
R
Dashti
D000328:Adult; D000368:Aged; D015992:Body Mass Index; D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D005269:Femur / Q000378:metabolism; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000453:epidemiology; D017698:Postmenopause; D012016:Reference Values; D012727:Sex Characteristics