[Determination of selected biomarkers can be used in monitoring oxidative stress in the course of chronic failure].
The aim of the study was to assess oxidative stress biomarkers considering the simplicity of their determination, invasiveness of material collection and their specificity. The following oxidative stress markers were evaluated: malonyldialdehyde, thiobarbituric acid reactive lipid peroxidation products, prostaglandin F2alpha, nitric oxide derivatives, nucleic acid damage products, advanced oxidation protein products and gas components in exhaled air: nitric oxide, hydrocarbons, isoprene, ethane. Analysis of the selected biomarkers indicates the usefulness of the determination of prostaglandin F2alpha, nucleic acid damage products, advanced oxidation protein products and gas components in the exhaled air as oxidative stress biomarkers in patients with chronic renal failure.
Zakład Fizjologii Doświadczalnej i Klinicznej UM w Lodzi.
Elbieta
E
Potargowicz
Jacek
J
Rysz
Ewa
E
Szerszenowicz
Robert
R
Olszewski
Dariusz
D
Nowak
D015415:Biomarkers / Q000378:metabolism*; D002070:Butadienes / Q000378:metabolism; D004980:Ethane / Q000378:metabolism; D045782:Hemiterpenes / Q000378:metabolism; D006801:Humans; D006838:Hydrocarbons / Q000378:metabolism; D007676:Kidney Failure, Chronic / Q000097:blood / Q000378:metabolism*; D008315:Malondialdehyde / Q000378:metabolism; D009569:Nitric Oxide / Q000378:metabolism; D009696:Nucleic Acids / Q000378:metabolism; D018384:Oxidative Stress; D010420:Pentanes / Q000378:metabolism; D011460:Prostaglandins F / Q000378:metabolism; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
D015415:Biomarkers; D002070:Butadienes; D045782:Hemiterpenes; D006838:Hydrocarbons; D009696:Nucleic Acids; D010420:Pentanes; D011460:Prostaglandins F; D017392:Thiobarbituric Acid Reactive Substances; C005059:isoprene; D009569:Nitric Oxide; D008315:Malondialdehyde; D004980:Ethane