Allosteric modulation of dopamine receptors.
Allosteric modulators allow for the fine-tuning of receptor responses to endogenous neurotransmitters and exogenous therapeutic agents. Different types of allosteric modulation of dopamine receptors are discussed as well as the significance of such modulation in the control of normal biological processes and in the treatment of disease.
Schetz
John A
JA
Department of Pharmacology and Neuroscience, University of North Texas Health Sciences Center, 3500 Camp Bowie Blvd., Fort Worth, TX 76107, USA. jschetz@hsc.unt.edu
D000584:Amiloride / Q000494:pharmacology; D000818:Animals; D006801:Humans; D006859:Hydrogen / Q000737:chemistry; D010455:Peptides / Q000494:pharmacology; D011954:Receptors, Dopamine / Q000737:chemistry / Q000187:drug effects*; D012964:Sodium / Q000737:chemistry; D013830:Thiadiazoles; D013844:Thiazoles / Q000494:pharmacology
D010455:Peptides; D011954:Receptors, Dopamine; C418425:SCH-202676; D013830:Thiadiazoles; D013844:Thiazoles; D000584:Amiloride; D006859:Hydrogen; D012964:Sodium