New assessment of a structural alphabet.
A statistical analysis of the Protein Databank (PDB) structures had led us to define a set of small 3D structural prototypes called Protein Blocks (PBs). This structural alphabet includes 16 PBs, each one defined by the (phi, psi) dihedral angles of 5 consecutive residues. Here, we analyze the effect of the enlargement of the PDB on the PBs' definition. The results highlight the quality of the 3D approximation ensured by the PBs. These last could be of great interest in ab initio modeling.
Equipe de Bioinformatique Genomique et Moleculaire (EBGM), INSERM U 726, Universite Denis DIDEROT - Paris 7, case 7113, 2, place Jussieu, 75251 Paris, France. debrevern@ebgm.jussieu.fr
Alexandre G
AG
de Brevern
D030562:Databases, Protein; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry*
D011506:Proteins