Colonic microbiota signatures across five northern European countries.
The composition of the colonic microbiota of 91 northern Europeans was characterized by fluorescent in situ hybridization using 18 phylogenetic probes. On average 75% of the bacteria were identified, and large interindividual variations were observed. Clostridium coccoides and Clostridium leptum were the dominant groups (28.0% and 25.2%), followed by the Bacteroides (8.5%). According to principal component analysis, no significant grouping with respect to geographic origin, age, or gender was observed.
Unité d'Ecologie et de Physiologie du Système Digestif, Institut National de la Recherche Agronomique, 78352 Jouy-en-Josas Cedex, France.
Christophe
C
Lay
Lionel
L
Rigottier-Gois
Kim
K
Holmstrøm
Mirjana
M
Rajilic
Elaine E
EE
Vaughan
Willem M
WM
de Vos
Matthew D
MD
Collins
Ralph
R
Thiel
Pawel
P
Namsolleck
Michaël
M
Blaut
Joël
J
Doré
D000293:Adolescent; D000328:Adult; D001439:Bacteroides / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D002648:Child; D003013:Clostridium / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D003106:Colon / Q000382:microbiology*; D005060:Europe; D005434:Flow Cytometry; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008875:Middle Aged; D015999:Multivariate Analysis