Identification of a novel HLA-A allele HLA-A*2451 in a Chinese donor.
A novel human leucocyte antigen-A (HLA-A) allele, A*2451, has been identified during routine sequence-specific oligonucleotide typing and sequence-based typing of a sample from a registered donor of the Chinese Marrow Donor Program. The A*2451 allele differs from the closest matching allele A*2415 by one nucleotide substitution in exon 3, nt 363 G-->A, resulting in an amino acid change from M ATG to I ATA at codon 121.
Li
J-P
JP
Liaoning Blood Center, Shenyang, P. R. China.
Liu
X-Z
XZ
Gao
H-F
HF
Liu
X
X
Chen
Y
Y
Li
X-F
XF
Zhe
Q
Q
Gao
J-B
JB
Zhang
X
X
Lv
Y-Z
YZ
Yang
L-Y
LY
Huang
X-Y
XY
Yu
Y-Y
YY
Yu
F-Q
FQ
Chi
L-P
LP
D000483:Alleles; D001483:Base Sequence; D001854:Bone Marrow Cells / Q000166:cytology; D002681:China; D017931:DNA Primers / Q000235:genetics; D005091:Exons; D005838:Genotype; D015234:HLA-A Antigens / Q000235:genetics*; D059871:HLA-A24 Antigen; D006801:Humans; D008969:Molecular Sequence Data; D009841:Oligonucleotides / Q000235:genetics
D017931:DNA Primers; D015234:HLA-A Antigens; C503970:HLA-A*24:51 antigen; D059871:HLA-A24 Antigen; D009841:Oligonucleotides