[Analysis of polychlorinated quaterphenyls in Yusho diagnosis].
The polychlorinated quaterphenyl (PCQ) concentrations in the blood are important discriminative parameters in Yusho patients. In this study, the analytical method of PCQ was improved, and a high speed and precision analysis could be achieved. A recovery test showed satisfactory recoveries of 99.5% (RSD4.8%, n = 5). Using this method, the authors analyzed 62 blood samples which were collected from the 2004 annual inspection for Kanemi rice oil poisoning. PCQ was detected in 20 blood samples (ranging from 0.03 to 4.15 ng/g). The average concentration was 2.07 ng/g in the pattern A (typical Yusho patients), 0.76 ng/g in the pattern B, 0.18 ng/g in the pattern BC and 0.01 ng/g in the pattern C, respectively.
Fukuoka Institute of Health and Environmental Sciences, 39, Mukaizano, Dazaifu-shi, Fukuoka 818-0135.
Yuki
Y
Ashizuka
Reiko
R
Nakagawa
Hironori
H
Hirakawa
Tsuguhide
T
Hori
Takao
T
Iida
D015415:Biomarkers / Q000097:blood; D002722:Chlorobenzenes / Q000097:blood*; D002849:Chromatography, Gas / Q000379:methods; D005506:Food Contamination; D006801:Humans; D012275:Oryza / Q000506:poisoning*; D010938:Plant Oils / Q000506:poisoning*; D011041:Poisoning / Q000175:diagnosis; D011078:Polychlorinated Biphenyls / Q000506:poisoning*
D015415:Biomarkers; D002722:Chlorobenzenes; D010938:Plant Oils; C022053:polychlorinated quaterphenyls; D011078:Polychlorinated Biphenyls