Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) polymorphisms in a Brazilian mixed population.
The GSTM1 and GSTT1 null genotype frequencies were significantly different between 658 nonblack and black healthy blood donors from a Brazilian mixed population (Rio de Janeiro). The GSTM1 phenotype distribution was not in Hardy-Weinberg equilibrium in either group, mainly because of an excess of the GSTM1*A/*B genotype.
Departamento de Genética, Instituto Oswaldo Cruz, FIOCRUZ, Av. Brasil 4365, 21045-900 Rio de Janeiro, RJ, Brazil.
Ana
A
Hatagima
Christiane F S
CF
Marques
Henrique
H
Krieger
Mary F
MF
Feitosa
D000293:Adolescent; D000328:Adult; D000483:Alleles; D044383:Black People / Q000235:genetics*; D001938:Brazil; D005260:Female; D005787:Gene Frequency; D014644:Genetic Variation; D005828:Genetics, Population; D005838:Genotype; D005982:Glutathione Transferase / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D011110:Polymorphism, Genetic; D044465:White People / Q000235:genetics*
D005982:Glutathione Transferase; C413545:glutathione S-transferase T1