AS2TS system for protein structure modeling and analysis.
We present a set of programs and a website designed to facilitate protein structure comparison and protein structure modeling efforts. Our protein structure analysis and comparison services use the LGA (local-global alignment) program to search for regions of local similarity and to evaluate the level of structural similarity between compared protein structures. To facilitate the homology-based protein structure modeling process, our AL2TS service translates given sequence-structure alignment data into the standard Protein Data Bank (PDB) atom records (coordinates). For a given sequence of amino acids, the AS2TS (amino acid sequence to tertiary structure) system calculates (e.g. using PSI-BLAST PDB analysis) a list of the closest proteins from the PDB, and then a set of draft 3D models is automatically created. Web services are available at http://as2ts.llnl.gov/.
Zemla
A
A
Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA 94550, USA.
Zhou
C Ecale
CE
Slezak
T
T
Kuczmarski
T
T
Rama
D
D
Torres
C
C
Sawicka
D
D
Barsky
D
D
D036022:Capsid Proteins / Q000737:chemistry; D030562:Databases, Protein; D020407:Internet; D008958:Models, Molecular; D011487:Protein Conformation; D020539:Sequence Analysis, Protein; D012984:Software; D040681:Structural Homology, Protein
D036022:Capsid Proteins