Electroconvulsive therapy for depression in a Parkinson's disease patient with bilateral subthalamic nucleus deep brain stimulators.
We report a patient with advanced Parkinson's disease (PD) who developed a recurrence of major depression with psychotic features after bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery. Electroconvulsive therapy (ECT) dramatically improved the depression without shifting electrode position or damaging the DBS hardware. This case suggests that ECT can be a safe and effective option for severe depression in PD patients treated with STN DBS.
Department of Clinical Neurosciences, Brown University Medical School, Providence, RI, USA. kelvin.chou@brown.edu
Kelvin L
KL
Chou
Howard I
HI
Hurtig
Jurg L
JL
Jaggi
Gordon H
GH
Baltuch
Rodney J
RJ
Pelchat
Daniel
D
Weintraub
D000978:Antiparkinson Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D046690:Deep Brain Stimulation; D003865:Major Depressive Disorder / Q000209:etiology* / Q000628:therapy*; D003987:Dibenzothiazepines / Q000627:therapeutic use; D004565:Electroconvulsive Therapy; D005260:Female; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000628:therapy; D000069348:Quetiapine Fumarate; D020531:Subthalamic Nucleus / Q000502:physiology*
D000978:Antiparkinson Agents; D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate; D007980:Levodopa