PatchDock and SymmDock: servers for rigid and symmetric docking.
Here, we describe two freely available web servers for molecular docking. The PatchDock method performs structure prediction of protein-protein and protein-small molecule complexes. The SymmDock method predicts the structure of a homomultimer with cyclic symmetry given the structure of the monomeric unit. The inputs to the servers are either protein PDB codes or uploaded protein structures. The services are available at http://bioinfo3d.cs.tau.ac.il. The methods behind the servers are very efficient, allowing large-scale docking experiments.
Schneidman-Duhovny
Dina
D
School of Computer Science, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Inbar
Yuval
Y
Nussinov
Ruth
R
Wolfson
Haim J
HJ
D000465:Algorithms; D020407:Internet; D008024:Ligands; D046912:Multiprotein Complexes / Q000737:chemistry*; D011487:Protein Conformation; D012984:Software; D014584:User-Computer Interface
D008024:Ligands; D046912:Multiprotein Complexes