The dynamic ER: experimental approaches and current questions.
The endoplasmic reticulum (ER) is an extremely plastic and dynamic organelle. Its size and shape can undergo drastic changes to meet changing demands for ER-related functions, or as a response to drugs or pathogens. Because of the ER's key functions in protein and lipid synthesis, this organelle is a hotbed of detailed molecular analysis.
UCSD Division of Biological Sciences, Section of Cell and Developmental Biology, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Christine M
CM
Federovitch
David
D
Ron
Randolph Y
RY
Hampton
D000818:Animals; D001402:B-Lymphocytes / Q000166:cytology / Q000378:metabolism; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D011489:Protein Denaturation; D017510:Protein Folding