Medical image registration with partial data.
We have developed a general-purpose registration algorithm for medical images and volumes. The transformation between images is modeled as locally affine but globally smooth, and explicitly accounts for local and global variations in image intensities. An explicit model of missing data is also incorporated, allowing us to simultaneously segment and register images with partial or missing data. The algorithm is built upon a differential multiscale framework and incorporates the expectation maximization algorithm. We show that this approach is highly effective in registering a range of synthetic and clinical medical images.
Periaswamy
Senthil
S
Siemens Medical Solutions USA, Inc., Malvern, PA 19355, USA. senthil.periaswamy@siemens.com
Farid
Hany
H
D000465:Algorithms; D001185:Artificial Intelligence; D001921:Brain / Q000033:anatomy & histology; D003198:Computer Simulation; D006257:Head / Q000033:anatomy & histology; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D016247:Information Storage and Retrieval / Q000379:methods*; D008954:Models, Biological; D015233:Models, Statistical; D010363:Pattern Recognition, Automated / Q000379:methods; D015203:Reproducibility of Results; D018401:Sample Size; D012680:Sensitivity and Specificity; D013382:Subtraction Technique