The potential and problems of screening for ovarian cancer.
Screening for ovarian cancer using tumor markers is simple but often associated with an increased rate of false negatives and a low rate of detection of early stage cancers. The transvaginal ultrasonic method, on the other hand, detects an increased number of Stage I cancers (about 70% of the total cancers detected), but it takes time. Our method is performed in a short time and is most suitable as a screening method. Although there is no established assessment of ovarian cancer screening, we have outlined the potential and the problems associated with it based on the reports published to date and the results of our study.
Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Hirosaki, Japan.
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Yokoyama
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Higuchi
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Mizunuma
D014408:Biomarkers, Tumor / Q000097:blood*; D018394:CA-125 Antigen / Q000097:blood*; D019160:Endosonography; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging; D018615:Ultrasonography, Doppler, Color
D014408:Biomarkers, Tumor; D018394:CA-125 Antigen