Outbreak of extended spectrum beta-lactamase-producing Klebsiella pneumoniae infection in a neonatal intensive care unit related to onychomycosis in a health care worker.
Four cases of infection by extended spectrum beta-lactamase-producing Klebsiella pneumoniae occurred in the neonatal intensive care unit. Isolation, empiric therapy change and education produced no effect. Newborn weekly colonization rates were 0-18.7%. One health care worker with onychomycosis was positive for extended spectrum beta-lactamase-producing K. pneumoniae. Isolates were identical by molecular typing. Outbreak was controlled when the health care worker was excluded from the neonatal intensive care unit.
Hospital Geral de Itapecerica da Serra, São Paulo, SP, Brazil. icarobski@uol.com.br
Icaro
I
Boszczowski
Christiane
C
Nicoletti
Dilma M T
DM
Puccini
Mônica
M
Pinheiro
Robson E
RE
Soares
Inneke M
IM
Van der Heijden
Silvia F
SF
Costa
Antonio A
AA
Barone
Anna S
AS
Levin
D000328:Adult; D000617:Aminoglycosides / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology; D004196:Disease Outbreaks; D024881:Drug Resistance, Bacterial; D006225:Hand / Q000382:microbiology; D006229:Hand Dermatoses / Q000150:complications / Q000382:microbiology; D006282:Health Personnel; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D007710:Klebsiella Infections / Q000453:epidemiology*; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000201:enzymology* / Q000302:isolation & purification; D014009:Onychomycosis / Q000150:complications; D001618:beta-Lactamases / Q000378:metabolism*
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D001618:beta-Lactamases