What can Busselton population health surveys tell us about asthma in older people?
WHAT WE NEED TO KNOW: Do the characteristics of asthma differ in people older than 55 years compared with younger people with respect to risk factors (atopy, airway hyper-responsiveness and genetic variation), smoking, lung function and other illness? How do inflammation and remodelling of airways vary with age and with duration and severity of asthma? WHAT WE NEED TO DO: Continue collecting prevalence data for asthma and its risk factors. Assess (i) period and cohort effects on asthma and its risk factors and (ii) interactions between age, smoking, severity and duration of asthma, lung function and airway responsiveness, and other concurrent disease. Measure airway responsiveness and exhaled nitric oxide to detect airway abnormalities in older people and relate this to the diagnoses of asthma and other diseases.
West Australian Sleep Disorders Research Institute/Department of Pulmonary Physiology, Queen Elizabeth II Medical Centre, Level 5, G Block, Hospital Avenue, Nedlands, WA 6009, Australia. ajames@it.net.au
Alan L
AL
James
Matthew W
MW
Knuiman
Helen C
HC
Bartholomew
Arthur Bill W
AB
Musk
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001249:Asthma / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D005853:Geriatrics; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012129:Respiratory Function Tests; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D014904:Western Australia / Q000453:epidemiology