TICO: a tool for improving predictions of prokaryotic translation initiation sites.
We provide the tool 'TICO' (Translation Initiation site COrrection) for improving the results of conventional gene finders for prokaryotic genomes with regard to exact localization of the translation initiation site (TIS). At the current state TICO provides an interface for direct post processing of the predictions obtained from the widely used program GLIMMER. Our program is based on a clustering algorithm for completely unsupervised scoring of potential TIS locations.


BACKGROUND
Our tool can be freely accessed through a web interface at http://tico.gobics.de/


BACKGROUND
maike@gobics.de
Tech
Maike
M
Abteilung Bioinformatik, Institut für Mikrobiologie und Genetik, Georg-August-Universität Göttingen Goldschmidtstrasse 1, 37077 Göttingen, Germany. maike@gobics.de
Pfeifer
Nico
N
Morgenstern
Burkhard
B
Meinicke
Peter
P
D000465:Algorithms; D001483:Base Sequence; D018387:Codon, Initiator / Q000235:genetics*; D016680:Genome, Bacterial; D008969:Molecular Sequence Data; D011387:Prokaryotic Cells; D014176:Protein Biosynthesis / Q000235:genetics*; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software
D018387:Codon, Initiator