BIOVERSE: enhancements to the framework for structural, functional and contextual modeling of proteins and proteomes.
We have made a number of enhancements to the previously described Bioverse web server and computational biology framework (http://bioverse.compbio.washington.edu). In this update, we provide an overview of the new features available that include: (i) expansion of the number of organisms represented in the Bioverse and addition of new data sources and novel prediction techniques not available elsewhere, including network-based annotation; (ii) reengineering the database backend and supporting code resulting in significant speed, search and ease-of use improvements; and (iii) creation of a stateful and dynamic web application frontend to improve interface speed and usability. Integrated Java-based applications also allow dynamic visualization of real and predicted protein interaction networks.
Department of Microbiology, University of Washington, Seattle, WA, USA.
Jason
J
McDermott
Michal
M
Guerquin
Zach
Z
Frazier
Aaron N
AN
Chang
Ram
R
Samudrala
D003196:Computer Graphics; D020407:Internet; D008958:Models, Molecular; D011487:Protein Conformation; D025941:Protein Interaction Mapping / Q000379:methods*; D011506:Proteins / Q000737:chemistry* / Q000502:physiology; D020543:Proteome / Q000737:chemistry* / Q000502:physiology; D012984:Software; D014584:User-Computer Interface
D011506:Proteins; D020543:Proteome