HIV superinfection.
Worldwide, 16 cases of HIV-1 superinfection in humans have been reported since 2002. Superinfection is defined as the reinfection of an individual who already has an established infection with a heterologous HIV strain. Controversy exists surrounding superinfection, because it has implications concerning our understanding of worldwide HIV diversity, individual immunity and disease progression, and vaccine development. Here, we review the current understanding of HIV superinfection.
University of California, San Diego, 92093, USA. davey@ucsd.edu
Davey M
DM
Smith
Douglas D
DD
Richman
Susan J
SJ
Little
D017088:AIDS-Related Opportunistic Infections / Q000145:classification / Q000453:epidemiology*; D014943:Global Health; D006801:Humans; D015163:Superinfection