The isolation, characterization and antifungal susceptibilities of Cryptococcus neoformans from bird excreta in Klang Valley, Malaysia.
The occurrence of Cryptococcus neoformans in bird excreta in Klang valley, Malaysia was determined in this study. Of 544 samples of bird excreta collected from a local zoo, pet shops and public areas, 20 strains of C. neoformans were isolated. All C. neoformans strains were serotype A and thus identified as C. neoformans variety grubii. All did not produce color changes on canavanine-glycine-bromothymol blue agar. All were of alpha-mating types, as determined by a pheromone-specific PCR assay. The antifungal susceptibility testing using agar diffusion method Neo-sensitabs showed that all were susceptible to amphotericin B, fluconazole and itraconazole.
Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. tayst@um.edu.my
S T
ST
Tay
H C
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Chai
S L
SL
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Hamimah
M Y
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Rohani
T S
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Soo-Hoo
D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology; D001715:Bird Diseases / Q000453:epidemiology / Q000469:parasitology*; D010856:Columbidae; D003453:Cryptococcosis / Q000453:epidemiology / Q000469:parasitology / Q000662:veterinary*; D003455:Cryptococcus neoformans / Q000187:drug effects* / Q000302:isolation & purification*; D016054:DNA, Protozoan / Q000737:chemistry / Q000235:genetics; D005243:Feces / Q000469:parasitology; D005779:Immunodiffusion / Q000662:veterinary; D008296:Malaysia / Q000453:epidemiology; D008826:Microbial Sensitivity Tests / Q000662:veterinary; D010675:Pheromones / Q000737:chemistry / Q000235:genetics; D016133:Polymerase Chain Reaction / Q000662:veterinary; D012703:Serotyping / Q000662:veterinary; D014505:Urban Population
D000935:Antifungal Agents; D016054:DNA, Protozoan; D010675:Pheromones