High number of circulating CD34+ cells in patients with myelophthisis.
Six patients with bone marrow micrometastases from solid cancers presented with increased numbers of circulating CD34+ cells; the CD34+ cell counts were very high in some cases. By contrast, no patient with metastatic cancer without bone marrow involvement showed raised numbers of circulating hemopoietic progenitors.
Ciancia
Rosanna
R
Martinelli
Vincenzo
V
Cosentini
Elena
E
Picardi
Marco
M
Petruzziello
Fara
F
Matano
Elide
E
Rotoli
Bruno
B
D000328:Adult; D000368:Aged; D000750:Anemia, Myelophthisic / Q000378:metabolism*; D018952:Antigens, CD34 / Q000097:blood*; D015214:Antigens, Differentiation, Myelomonocytic / Q000378:metabolism; D001853:Bone Marrow / Q000378:metabolism; D001854:Bone Marrow Cells / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis
D018952:Antigens, CD34; D015214:Antigens, Differentiation, Myelomonocytic