Screen detected sclerosing lymphocytic lobulitis and amyloid of the breast in the same patient--a possible causal link.
Sclerosing lymphocytic lobulitis (SLL) and amyloidosis of the breast are both rare. We report the case of a 59 year old woman who presented with suspicious microcalcifications on routine screening mammography. Wire-guided excision biopsy showed features typical of SLL but also localised amyloid deposits within the specimen. Amyloidosis and SLL may have similar immunological causes. This patient represents the first documented association of these two disorders.
Department of Radiology, Southampton General Hospital, Southampton, UK. mandy1@doctors.org.uk
C A
CA
Turner
C M E
CM
Rubin
G T
GT
Royle
M
M
Flynn
J M
JM
Theaker
D000686:Amyloidosis / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D001707:Biopsy, Needle; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D012598:Sclerosis / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology