Spatial control of protein synthesis.
Previously used to provide temporal control over cellular processes, "photocaged" small molecules can impart spatial control to in vitro models. In this issue of Chemistry & Biology, the Dore and Schuman labs report a system to block protein synthesis in a spatially confined manner with a photo-caged form of anisomycin [1].
Koh
John
J
Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716, USA.
D000818:Animals; D000841:Anisomycin / Q000737:chemistry* / Q000494:pharmacology*; D010777:Photochemistry; D014176:Protein Biosynthesis / Q000187:drug effects*
D000841:Anisomycin