Outbreak of extended spectrum beta-lactamase-producing Klebsiella pneumoniae infection in a neonatal intensive care unit related to onychomycosis in a health care worker.
Four cases of infection by extended spectrum beta-lactamase-producing Klebsiella pneumoniae occurred in the neonatal intensive care unit. Isolation, empiric therapy change and education produced no effect. Newborn weekly colonization rates were 0-18.7%. One health care worker with onychomycosis was positive for extended spectrum beta-lactamase-producing K. pneumoniae. Isolates were identical by molecular typing. Outbreak was controlled when the health care worker was excluded from the neonatal intensive care unit.
Boszczowski
Icaro
I
Hospital Geral de Itapecerica da Serra, São Paulo, SP, Brazil. icarobski@uol.com.br
Nicoletti
Christiane
C
Puccini
Dilma M T
DM
Pinheiro
Mônica
M
Soares
Robson E
RE
Van der Heijden
Inneke M
IM
Costa
Silvia F
SF
Barone
Antonio A
AA
Levin
Anna S
AS
D000328:Adult; D000617:Aminoglycosides / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology; D004196:Disease Outbreaks; D024881:Drug Resistance, Bacterial; D006225:Hand / Q000382:microbiology; D006229:Hand Dermatoses / Q000150:complications / Q000382:microbiology; D006282:Health Personnel; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D007710:Klebsiella Infections / Q000453:epidemiology*; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000201:enzymology* / Q000302:isolation & purification; D014009:Onychomycosis / Q000150:complications; D001618:beta-Lactamases / Q000378:metabolism*
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D001618:beta-Lactamases