GlyProt: in silico glycosylation of proteins.
GlyProt (http://www.glycosciences.de/glyprot/) is a web-based tool that enables meaningful N-glycan conformations to be attached to all the spatially accessible potential N-glycosylation sites of a known three-dimensional (3D) protein structure. The probabilities of physicochemical properties such as mass, accessible surface and radius of gyration are calculated. The purpose of this service is to provide rapid access to reliable 3D models of glycoproteins, which can subsequently be refined by using more elaborate simulations and validated by comparing the generated models with experimental data.
Bohne-Lang
Andreas
A
German Cancer Research Center Heidelberg, Central Spectroscopy-Molecular Modeling Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany. a.bohne@dkfz-heidelberg.de
von der Lieth
Claus-Wilhelm
CW
D019295:Computational Biology; D006023:Glycoproteins / Q000737:chemistry*; D006031:Glycosylation; D006801:Humans; D020407:Internet; D008958:Models, Molecular; D011487:Protein Conformation; D020033:Protein Isoforms / Q000737:chemistry; D012984:Software
D006023:Glycoproteins; D020033:Protein Isoforms