How and when to use mitomycin-C in refractive surgery.
OBJECTIVE
Mitomycin-C is an antimetabolite that has seen increased use in ophthalmology over the past several decades. From glaucoma surgery to the management of various corneal disorders, mitomycin-C seems to be a viable tool in the management of scar and haze formation.


RESULTS
With the constant evolution of refractive surgery, mitomycin-C has come to the forefront as a modulator of corneal wound healing after excimer laser surface ablation.


CONCLUSIONS
This article will describe the various indications, techniques, and current trends of mitomycin-C application in corneal refractive surgery.
Lacayo
Gaston O
GO
Department of Ophthalmology, Rush University Medical Center, Chicago, Illinois, USA.
Majmudar
Parag A
PA
D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use*; D003315:Cornea / Q000601:surgery*; D048988:Corneal Surgery, Laser; D006801:Humans; D016685:Mitomycin / Q000627:therapeutic use*; D054140:Refractive Surgical Procedures; D014945:Wound Healing / Q000187:drug effects
D000903:Antibiotics, Antineoplastic; D016685:Mitomycin