Depression following acute myocardial infarction: a prospective relationship with ongoing health and function.
The relationship between baseline depression and health-related quality of life were examined in a cohort of patients after hospitalization due to acute myocardial infarction (N=196). Patients were assessed for presence of mood disturbance, anxiety, and quality of life at the time of hospitalization and again 4 months later. Baseline assessment was used to assign subjects to a depressed or a nondepressed group. Adjusting for preinfarction quality of life, in-hospital anxiety, and demographic variables, depression was prospectively and independently related to reduced global health at 4 months as well as reduced overall mental health-including vitality, psychological health, and social function-and increased role interference from psychological problems.
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. JFAUERBA@JHMI.edu
James A
JA
Fauerbach
David E
DE
Bush
Brett D
BD
Thombs
Una D
UD
McCann
Joshua
J
Fogel
Roy C
RC
Ziegelstein
D000368:Aged; D003710:Demography; D003863:Depression / Q000175:diagnosis* / Q000209:etiology*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000523:psychology*; D011446:Prospective Studies; D011788:Quality of Life / Q000523:psychology; D012720:Severity of Illness Index