Effects of fenugreek seed extract in obese mice fed a high-fat diet.
It was found that fenugreek seed extract reduced the body weight gain induced by a high-fat diet in obese mice. The extract decreased plasma triglyceride gain induced by oil administration. The major component of the extract, 4-hydroxyisoleucine, also decreased plasma triglyceride gain. Consequently, fenugreek seed extract is expected to prevent the obesity induced by a high-fat diet.
Handa
Toshiaki
T
Laboratory of Nutraceuticals and Functional Foods Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, Konan, Tokyo, Japan.
Yamaguchi
Kohji
K
Sono
Yoshikatsu
Y
Yazawa
Kazunaga
K
D000273:Adipose Tissue / Q000187:drug effects; D000818:Animals; D019440:Anti-Obesity Agents / Q000494:pharmacology*; D004041:Dietary Fats; D005260:Female; D008099:Liver / Q000187:drug effects; D051379:Mice; D008820:Mice, Obese; D009929:Organ Size / Q000187:drug effects; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D012639:Seeds / Q000737:chemistry; D014280:Triglycerides / Q000097:blood; D029910:Trigonella / Q000737:chemistry*; D015430:Weight Gain
D019440:Anti-Obesity Agents; D004041:Dietary Fats; D010936:Plant Extracts; D014280:Triglycerides