Polymyalgia rheumatica in primary Sjögren's syndrome.
The aim of the study was to describe the clinical and laboratory aspects of primary Sjögren's syndrome (pSS) associated with polymyalgia rheumatica (PMR). The retrospective study compares the clinical and laboratory aspects of patients with pSS associated with PMR on a relatively large cohort of patients (n=16) and pSS patients without PMR (n=531). The prevalence of PMR among pSS patients was 3%, while in the average population, the prevalence of PMR is only 0.75%. PMR developed 8.7 years after the diagnosis of pSS in the older female pSS population (over 50 years of age), and in those with only glandular features. Interestingly the pSS/PMR patients had hypo gammaglobuline levels, while in the pSS patient group hypergammaglobulinaemia presented. Furthermore, positive ANA serology was more frequent among pSS/PMR patients. Since the clinical management of pSS/PMR is different from pSS, a better understanding of this clinical entity is essential.
Szodoray
Peter
P
Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Armauer Hansen Bldg, 5021 Bergen, Norway. peter.szodoray@gades.uib.no
Jonsson
Roland
R
Brun
Johan G
JG
Zeher
Margit
M
D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011111:Polymyalgia Rheumatica / Q000150:complications*; D012189:Retrospective Studies; D012737:Sex Factors; D012859:Sjogren's Syndrome / Q000150:complications*