Copper-catalyzed stereospecific N-allenylations of amides. Syntheses of optically enriched chiral allenamides.
[reaction: see text] Syntheses of chiral allenamides via a stereospecific amidation of optically enriched allenyl iodides using catalytic copper(I) salt and N,N'-dimethylethylene-diamine are described here.
Department of Chemistry, University of Minnesota, Minneapolis, 55455, USA.
Lichun
L
Shen
Richard P
RP
Hsung
Yanshi
Y
Zhang
Jennifer E
JE
Antoline
Xuejun
X
Zhang
D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007202:Indicators and Reagents; D015394:Molecular Structure; D013237:Stereoisomerism
D000577:Amides; D007202:Indicators and Reagents; D003300:Copper