(1)H and (13)C NMR studies of asymmetrically substituted bis- and tris-Tröger's bases.
The (1)H and (13)C NMR spectra of two stereoisomeric bis-Tröger's bases and four stereoisomeric tris-Tröger's bases asymmetrically substituted on the external aromatic rings were recorded and the corresponding signals assigned. The relative configuration of the stereogenic units has been unequivocally determined on the basis of homoallylic couplings and NOE experiments.
Instituto de Química Médica, Centro de Química Orgánica Manuel Lora-Tamayo, Juan de la Cierva 3, E-28006 Madrid, Spain.
J
J
Elguero
A
A
Fruchier
T
T
Mas
C
C
Pardo
D001392:Azocines / Q000737:chemistry*; D002247:Carbon Isotopes; D009682:Magnetic Resonance Spectroscopy / Q000379:methods* / Q000592:standards*; D008968:Molecular Conformation; D011522:Protons; D012016:Reference Values; D013237:Stereoisomerism
D001392:Azocines; D002247:Carbon Isotopes; D011522:Protons; C083830:Troeger's base