Bilateral blindness after starting highly active antiretroviral treatment in a patient with HIV infection and cryptococcal meningitis.
A 26-year-old HIV-seropositive Caucasian man with cryptococcal meningitis developed permanent bilateral blindness shortly after starting highly active antiretroviral treatment. The blindness may have been a consequence of an immune reactivation inflammatory syndrome caused by this treatment.
De Schacht
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C
Departement Klinische Wetenschappen, Instituut voor Tropische Geneeskunde, Nationalestraat 155, B-2000 Antwerpen.
Smets
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RM
Callens
S
S
Colebunders
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R
D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D001766:Blindness / Q000139:chemically induced*; D015897:Comorbidity; D006679:HIV Seropositivity / Q000188:drug therapy* / Q000453:epidemiology*; D006801:Humans; D008297:Male; D016919:Meningitis, Cryptococcal / Q000453:epidemiology*