Autosomal dominant osteopetrosis and maxillomandibular osteomyelitis.
Osteopetroses represent a heterogeneous group of rare, hereditary bony dysplasias. They range from a devastating neurometabolic disease (including severe malignant infantile osteopetrosis) to 2 more benign conditions principally affecting adults: autosomal dominant osteopetrosis (ADO) type I and type II. The present study describes the maxillofacial manifestations associated with the 2 subgroups of ADO. In this paper, we present the oldest patient described in the literature with ADO type I (76 years old). We also document the first ADO type II patient described in the literature with synchronic osteomyelitis of the mandible and the maxilla.
Junquera
Luis
L
Department of Oral and Maxillofacial Surgery, University of Oviedo, Central Hospital of Asturias, Spain. junquera@sci.cpd.uniovi.es
Rodríguez-Recio
Cristian
C
Villarreal
Pedro
P
García-Consuegra
Luis
L
D000368:Aged; D025063:Chromosome Disorders / Q000150:complications / Q000235:genetics* / Q000473:pathology*; D005260:Female; D006801:Humans; D007571:Jaw Diseases / Q000000981:diagnostic imaging / Q000209:etiology; D008297:Male; D019767:Maxillofacial Abnormalities / Q000000981:diagnostic imaging / Q000209:etiology*; D008875:Middle Aged; D010019:Osteomyelitis / Q000000981:diagnostic imaging / Q000209:etiology; D010022:Osteopetrosis / Q000150:complications / Q000235:genetics* / Q000473:pathology*; D014057:Tomography, X-Ray Computed