[Age of onset of different malignant tumors in childhood].
OBJECTIVE
To identify the main age of onset of different malignant tumors in childhood and to describe the distribution of the different tumors in each pediatric age group.


METHODS
Descriptive survey was used. We reviewed the files of six Mexico City hospitals from 1980 to 1992. We included 4595 cases divided into 13 types of cancer. Peak age was defined when in that year we encountered a frequency equal to or below 10 % of the cases.


RESULTS
Peak ages for hepatic, sympathetic nervous system, germ cell tumors, retinoblastoma and rhabdomyosarcoma were between 2 and 3 years of age. Wilms' tumor appeared between the first and fourth years; central nervous system tumors between 4 and 5 years; acute lymphoblastic leukemia between 2 and 4 years; non-Hodgkin's lymphomas between 3 and 6 years; Hodgkin's disease between 4 and 8 years; bone tumors between 10 and 14 years. In acute myeloid leukemia and carcinomas no age peak was found.


CONCLUSIONS
Lymphomas present an age peak different from that reported in developed countries. In neonates and infants, the most frequent tumor was retinoblastoma.
Mejía Aranguré
Juan Manuel
JM
Unidad de Investigación Médica en Epidemiología Clínica, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Insituto Mexicano del Seguro Social. jmejiaa@cis.gob.mx
Flores Aguilar
Hilario
H
Juárez Muñoz
Irina
I
Vázquez Langle
José
J
Games Eternod
Juan
J
Pérez Saldívar
María Luisa
ML
Ortega Alvarez
Manuel Carlos
MC
Rendón Macías
Mario Enrique
ME
Gutiérrez
Arturo Fajardo
AF
D000293:Adolescent; D017668:Age of Onset; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008800:Mexico; D009369:Neoplasms / Q000145:classification / Q000453:epidemiology*; D012042:Registries; D012189:Retrospective Studies