Histologic evaluation of mineralized and demineralized freeze-dried bone allograft for ridge and sinus augmentations.
The objective of this study was to quantify new bone formation from biopsies of demineralized freeze-dried bone allograft (DFDBA) and freeze-dried bone allograft (FDBA) following ridge and sinus augmentations. Ninety-three patients who received maxillary sinus or ridge augmentation grafts agreed to core biopsies of their grafts when the implants were placed. Samples ranged from 6 to 36 months postgrafting. These samples were sectioned, stained, and examined histomorphometrically Seventy-two FDBA and 21 DFDBA samples were examined, and the mean percentages of new bone formed were 41.89% and 41.74%, respectively. There was no statistical difference, irrespective of graft site.
Department of Orthodontics, The University of Texas Health Science Center, San Antonio, Texas 78229-3900, USA.
Gerald V
GV
Cammack
Myron
M
Nevins
Donald S
DS
Clem
John P
JP
Hatch
James T
JT
Mellonig
D000328:Adult; D000368:Aged; D000540:Alveolar Ridge Augmentation / Q000379:methods; D001706:Biopsy; D018775:Bone Demineralization Technique; D001857:Bone Matrix / Q000637:transplantation*; D001861:Bone Regeneration; D016025:Bone Transplantation / Q000379:methods*; D005260:Female; D005612:Freeze Drying; D006801:Humans; D008297:Male; D008443:Maxillary Sinus / Q000601:surgery; D008875:Middle Aged; D013516:Oral Surgical Procedures, Preprosthetic / Q000379:methods*; D012189:Retrospective Studies; D018709:Statistics, Nonparametric