[Effect of phillyrin on the anti-obesity in nutritive obesity mice].
OBJECTIVE
To study on the anti-obesity effect of phillyrin in nutritive obesity mice.


METHODS
The alimentary obesity model was established by hyperalimentation. The wet weight of fat, fat index, number of fat cells per unit visual field, Lee's index, jejunum microvillus area, serum triglyceride and cholesterol were selected to observe the anti-obesity effect of phillyrin.


RESULTS
Phillyrin could lower wet weight of fat (P < 0.01), fat index (P < 0.05 or P < 0.01), diameter of fat cell and Lee's index (P < 0.05), decrease the jejunum microvillus area, lower the level of serum triglyceride and cholesterol.


CONCLUSIONS
Phillyrin has anti-obesity effect in nutritive obesity mice.
Department of Life Sciences, Xi'an College of Arts and Science, Xi'an 710065.
Yongmei
Y
Zhao
Farong
F
Li
Jianxiong
J
Yang
Xiaoning
X
An
Minjuan
M
Zhou
D000818:Animals; D019440:Anti-Obesity Agents / Q000494:pharmacology; D002784:Cholesterol / Q000097:blood*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D031657:Forsythia / Q000737:chemistry*; D005960:Glucosides / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D009765:Obesity / Q000097:blood / Q000188:drug therapy / Q000473:pathology*; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D014280:Triglycerides / Q000097:blood
D019440:Anti-Obesity Agents; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D014280:Triglycerides; D002784:Cholesterol; C075528:phillyrin